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Search of human proteins with 154354979
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154354979 myosin X [Homo sapiens]
(2058 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154354979 myosin X [Homo sapiens] 4137 0.0
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 651 0.0
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 651 0.0
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 651 0.0
gi|122937512 myosin VIIB [Homo sapiens] 599 e-171
gi|118402590 myosin XV [Homo sapiens] 594 e-169
gi|122937345 myosin VB [Homo sapiens] 555 e-157
gi|153945715 myosin VC [Homo sapiens] 548 e-155
gi|215982794 myosin VA isoform 2 [Homo sapiens] 531 e-150
gi|215982791 myosin VA isoform 1 [Homo sapiens] 531 e-150
gi|92859701 myosin VI [Homo sapiens] 518 e-146
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 513 e-145
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 513 e-145
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 509 e-143
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 509 e-143
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 497 e-140
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 496 e-139
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 495 e-139
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 491 e-138
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 491 e-138
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 489 e-138
gi|194328685 myosin IB isoform 1 [Homo sapiens] 486 e-136
gi|240120050 myosin IB isoform 1 [Homo sapiens] 486 e-136
gi|44889481 myosin IB isoform 2 [Homo sapiens] 483 e-136
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 483 e-136
gi|124494247 myosin IC isoform b [Homo sapiens] 483 e-136
gi|124494238 myosin IC isoform a [Homo sapiens] 483 e-136
gi|124494240 myosin IC isoform c [Homo sapiens] 483 e-136
gi|156104908 myosin heavy chain 6 [Homo sapiens] 483 e-136
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 483 e-136
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 4137 bits (10728), Expect = 0.0
Identities = 2058/2058 (100%), Positives = 2058/2058 (100%)
Query: 1 MDNFFTEGTRVWLRENGQHFPSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPT 60
MDNFFTEGTRVWLRENGQHFPSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPT
Sbjct: 1 MDNFFTEGTRVWLRENGQHFPSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPT 60
Query: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQ 120
NEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQ
Sbjct: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQ 120
Query: 121 YSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ 180
YSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ
Sbjct: 121 YSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ 180
Query: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240
SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI
Sbjct: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240
Query: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTI 300
VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTI
Sbjct: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTI 300
Query: 301 SDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTALGRSAE 360
SDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTALGRSAE
Sbjct: 301 SDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTALGRSAE 360
Query: 361 LLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSR 420
LLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSR
Sbjct: 361 LLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSR 420
Query: 421 IKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLV 480
IKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLV
Sbjct: 421 IKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLV 480
Query: 481 WEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRVA 540
WEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRVA
Sbjct: 481 WEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRVA 540
Query: 541 VNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTL 600
VNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTL
Sbjct: 541 VNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTL 600
Query: 601 KCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYS 660
KCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYS
Sbjct: 601 KCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYS 660
Query: 661 GMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLG 720
GMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLG
Sbjct: 661 GMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLG 720
Query: 721 KTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFL 780
KTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFL
Sbjct: 721 KTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFL 780
Query: 781 LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840
LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE
Sbjct: 781 LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840
Query: 841 RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL 900
RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL
Sbjct: 841 RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL 900
Query: 901 QRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
QRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERS
Sbjct: 901 QRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
Query: 961 LSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHGHSDQRT 1020
LSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHGHSDQRT
Sbjct: 961 LSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHGHSDQRT 1020
Query: 1021 SGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAG 1080
SGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAG
Sbjct: 1021 SGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTYCMPQNAG 1080
Query: 1081 DLPSPDGDYDYDQDDYEDGAITSGSSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEG 1140
DLPSPDGDYDYDQDDYEDGAITSGSSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEG
Sbjct: 1081 DLPSPDGDYDYDQDDYEDGAITSGSSVTFSNSYGSQWSPDYRCSVGTYNSSGAYRFSSEG 1140
Query: 1141 AQSSFEDSEEDFDSRFDTDDELSYRRDSVYSCVTLPYFHSFLYMKGGLMNSWKRRWCVLK 1200
AQSSFEDSEEDFDSRFDTDDELSYRRDSVYSCVTLPYFHSFLYMKGGLMNSWKRRWCVLK
Sbjct: 1141 AQSSFEDSEEDFDSRFDTDDELSYRRDSVYSCVTLPYFHSFLYMKGGLMNSWKRRWCVLK 1200
Query: 1201 DETFLWFRSKQEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGT 1260
DETFLWFRSKQEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGT
Sbjct: 1201 DETFLWFRSKQEALKQGWLHKKGGGSSTLSRRNWKKRWFVLRQSKLMYFENDSEEKLKGT 1260
Query: 1261 VEVRTAKEIIDNTTKENGIDIIMADRTFHLIAESPEDASQWFSVLSQVHASTDQEIQEMH 1320
VEVRTAKEIIDNTTKENGIDIIMADRTFHLIAESPEDASQWFSVLSQVHASTDQEIQEMH
Sbjct: 1261 VEVRTAKEIIDNTTKENGIDIIMADRTFHLIAESPEDASQWFSVLSQVHASTDQEIQEMH 1320
Query: 1321 DEQANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHHWITLLQ 1380
DEQANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHHWITLLQ
Sbjct: 1321 DEQANPQNAVGTLDVGLIDSVCASDSPDRPNSFVIITANRVLHCNADTPEEMHHWITLLQ 1380
Query: 1381 RSKGDTRVEGQEFIVRGWLHKEVKNSPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLG 1440
RSKGDTRVEGQEFIVRGWLHKEVKNSPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLG
Sbjct: 1381 RSKGDTRVEGQEFIVRGWLHKEVKNSPKMSSLKLKKRWFVLTHNSLDYYKSSEKNALKLG 1440
Query: 1441 TLVLNSLCSVVPPDEKIFKETGYWNVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDTKA 1500
TLVLNSLCSVVPPDEKIFKETGYWNVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDTKA
Sbjct: 1441 TLVLNSLCSVVPPDEKIFKETGYWNVTVYGRKHCYRLYTKLLNEATRWSSAIQNVTDTKA 1500
Query: 1501 PIDTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINLNLLKDK 1560
PIDTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINLNLLKDK
Sbjct: 1501 PIDTPTQQLIQDIKENCLNSDVVEQIYKRNPILRYTHHPLHSPLLPLPYGDINLNLLKDK 1560
Query: 1561 GYTTLQDEAIKIFNSLQQLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTNKVPHP 1620
GYTTLQDEAIKIFNSLQQLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTNKVPHP
Sbjct: 1561 GYTTLQDEAIKIFNSLQQLESMSDPIPIIQGILQTGHDLRPLRDELYCQLIKQTNKVPHP 1620
Query: 1621 GSVGNLYSWQILTCLSCTFLPSRGILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTK 1680
GSVGNLYSWQILTCLSCTFLPSRGILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTK
Sbjct: 1621 GSVGNLYSWQILTCLSCTFLPSRGILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTK 1680
Query: 1681 CREFVPSRDEIEALIHRQEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLAMEDSRN 1740
CREFVPSRDEIEALIHRQEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLAMEDSRN
Sbjct: 1681 CREFVPSRDEIEALIHRQEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLAMEDSRN 1740
Query: 1741 MFALFEYNGHVDKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKD 1800
MFALFEYNGHVDKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKD
Sbjct: 1741 MFALFEYNGHVDKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKD 1800
Query: 1801 SVEFAFMFEQAHEAVIHGHHPAPEENLQVLAALRLQYLQGDYTLHAAIPPLEEVYSLQRL 1860
SVEFAFMFEQAHEAVIHGHHPAPEENLQVLAALRLQYLQGDYTLHAAIPPLEEVYSLQRL
Sbjct: 1801 SVEFAFMFEQAHEAVIHGHHPAPEENLQVLAALRLQYLQGDYTLHAAIPPLEEVYSLQRL 1860
Query: 1861 KARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIKEEVSSA 1920
KARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIKEEVSSA
Sbjct: 1861 KARISQSTKTFTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIKEEVSSA 1920
Query: 1921 RASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAV 1980
RASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAV
Sbjct: 1921 RASIIDKWRKFQGMNQEQAMAKYMALIKEWPGYGSTLFDVECKEGGFPQELWLGVSADAV 1980
Query: 1981 SVYKRGEGRPLEVFQYEHILSFGAPLANTYKIVVDERELLFETSEVVDVAKLMKAYISMI 2040
SVYKRGEGRPLEVFQYEHILSFGAPLANTYKIVVDERELLFETSEVVDVAKLMKAYISMI
Sbjct: 1981 SVYKRGEGRPLEVFQYEHILSFGAPLANTYKIVVDERELLFETSEVVDVAKLMKAYISMI 2040
Query: 2041 VKKRYSTTRSASSQGSSR 2058
VKKRYSTTRSASSQGSSR
Sbjct: 2041 VKKRYSTTRSASSQGSSR 2058
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 651 bits (1679), Expect = 0.0
Identities = 376/954 (39%), Positives = 557/954 (58%), Gaps = 104/954 (10%)
Query: 7 EGTRVWLREN-GQHFP----STVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTN 61
+G VW+ GQ F + V C G V D TH K MHPT+
Sbjct: 6 QGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIK--PMHPTS 63
Query: 62 EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY 121
GV+DM L +L+ I+ NL RY+ + IYTY GSIL +VNPYQ + +Y P + QY
Sbjct: 64 VHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQ-LLSIYSPEHIRQY 122
Query: 122 SRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQS 181
+ + +GE+PPHIFAIA+ CY + + +QC +ISGESGAGKTESTKLIL+FL+ IS Q
Sbjct: 123 TNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQH 182
Query: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
S +E+ +LE++PI+EAFGNAKT+ N+NSSRFGK++ ++ ++G I+G +I
Sbjct: 183 ---------SWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIE 233
Query: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTIS 301
YLLEK+RV RQ ERNYH+FY +L G+ +++++ L +Y+YL C+ +
Sbjct: 234 QYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRV 293
Query: 302 DQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIE-----FITAGGAQVSFKTALG 356
D + + + +AM V+ F+ E E+S+LLA ILHLGN++ F +V F +L
Sbjct: 294 DSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLA 353
Query: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
+A LL ++P L LT R++ RGE + TPL+ +QA+D RD+ +Y F W++ K
Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDK 413
Query: 417 INSRI--KGNEDFK----SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLE 470
IN+ I ++D K SIG+LDIFGFENF VN FEQ IN+ANE LQ++F +H+F LE
Sbjct: 414 INAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLE 473
Query: 471 QLEYSREGLVWEDIDWIDNGECLDLI-EKKLGLLALINEESHFPQATDSTLLEKLHSQHA 529
Q EY E + W I++ DN + LD+I K + +++LI+EES FP+ TD+T+L KL+SQH
Sbjct: 474 QEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHK 533
Query: 530 NNHFYVKPRVAVNN----FGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIY 585
N Y+ P+ NN FG+ H+AG V Y+ +G LEKNRDT D++ L+ SR FI
Sbjct: 534 LNANYIPPK---NNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIK 590
Query: 586 DLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMP 645
+F+ + ++ R PT+SSQFK SL LM TL + PFFVRCIKPN K P
Sbjct: 591 QIFQ------ADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKP 644
Query: 646 DQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLA---LPEDVRGK 702
FD+ + + QLRYSGM+ET+RIR+AGY +R F +F +RY+VL+ + D+RG
Sbjct: 645 MLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGT 704
Query: 703 CTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQY 762
C + + ++ +WQ+GKTK+FL++ + LE R++ ++ ++++ + GF R +
Sbjct: 705 CQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNF 764
Query: 763 RKVLYCVVIIQ---------KNY------------------------------------- 776
K+ +IQ KNY
Sbjct: 765 LKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARC 824
Query: 777 RAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK--REQEEKKKQEEEEKKKRE- 833
RA+L+R+ F H A + Q RG IARR++++L AE R + EK + EEEK ++E
Sbjct: 825 RAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEM 884
Query: 834 -----EEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
+EE ER+ + R A+L + E +EL+ + ++++ EL ++E+ +
Sbjct: 885 SAKKAKEEAERKHQERLAQLAREDAE-----RELKEKEAARRKKELLEQMERAR 933
Score = 60.8 bits (146), Expect = 1e-08
Identities = 66/251 (26%), Positives = 109/251 (43%), Gaps = 20/251 (7%)
Query: 1599 LRP-LRDELYCQLIKQTNKVPHPGSVGNLYSWQILT-CLSCTFLPSRGILKYLKFHLKRI 1656
LRP LRDE+YCQ+ KQ P S W +++ C+ C F PS +KYL+ I
Sbjct: 1163 LRPALRDEIYCQISKQLTHNPSKSSYAR--GWILVSLCVGC-FAPSEKFVKYLR---NFI 1216
Query: 1657 REQFPGSEMEKYALFTYESLKKT---KCREFVPSRDEIEALIHRQEMTSTVYCHGGGSCK 1713
PG YA + E L++T R PS E++A ++ + V G +
Sbjct: 1217 HGGPPG-----YAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIMLPVTFMDGTTKT 1271
Query: 1714 ITINSHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAA 1773
+ +S TTA E+ L ++++D V V D +++ E+ A
Sbjct: 1272 LLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVMDAISQCEQYAK 1331
Query: 1774 T--SEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPEENLQVLA 1831
++ + PW+ +F+ F + +D+V +++Q V G + +E+ LA
Sbjct: 1332 EQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEYRCEKED--DLA 1389
Query: 1832 ALRLQYLQGDY 1842
L Q DY
Sbjct: 1390 ELASQQYFVDY 1400
Score = 54.3 bits (129), Expect = 1e-06
Identities = 100/457 (21%), Positives = 177/457 (38%), Gaps = 80/457 (17%)
Query: 1601 PLRDELYCQLIKQT--NKVPHPGSVGNLYSWQILTCLSCTFLPSRGILKYLKFHLKRIRE 1658
PL+DE Y Q++KQ N + + G W++L + F PS +L H++R +
Sbjct: 1770 PLKDEAYVQILKQLTDNHIRYSEERG----WELLWLCTGLFPPSNILLP----HVQRFLQ 1821
Query: 1659 QFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHRQ-EMTSTVYCHGGGSCKITIN 1717
+ L + + R++ P E+EA+ H+ ++ VY +
Sbjct: 1822 SRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVE 1881
Query: 1718 SHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADV---LAKFEKLAAT 1774
S T A + + + L ++ S F+LF ++ D L + K A
Sbjct: 1882 SSTKAKDFCQNIATRLLLKSSEG-FSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARP 1940
Query: 1775 SEVGDLPWKFYFKLYCF-LDTDNVP-KDSV-EFAFMFEQAHEAVIHGHHPAPEENLQVLA 1831
+ G +P Y + L T VP KD + + F + Q + G+H E + L
Sbjct: 1941 IKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLG 2000
Query: 1832 AL--RLQYLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTL 1889
AL R+++ + D + +IP L Q L ++S
Sbjct: 2001 ALIYRVKF-EEDKSYFPSIPKLLRELVPQDLIRQVSP----------------------- 2036
Query: 1890 RRSFRTGSVVRQKVEEEQMLDMWIKEEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKE 1949
D W + SI+ + K G ++E+A ++ LI +
Sbjct: 2037 --------------------DDW--------KRSIVAYFNKHAGKSKEEAKLAFLKLIFK 2068
Query: 1950 WPGYGSTLFDVECKEGGFPQELWLGVSADAVSVYKRGEGRPLEVFQYEHILSFGAPLANT 2009
WP +GS F+ + E FP+ L + ++ VS+ L + I ++ + NT
Sbjct: 2069 WPTFGSAFFE-QTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNWSS--GNT 2125
Query: 2010 YKIV-----VDERELLFETSEVVDVAKLMKAYISMIV 2041
Y + V +LL ETS + L+ +YIS ++
Sbjct: 2126 YFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQML 2162
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 651 bits (1679), Expect = 0.0
Identities = 376/954 (39%), Positives = 557/954 (58%), Gaps = 104/954 (10%)
Query: 7 EGTRVWLREN-GQHFP----STVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTN 61
+G VW+ GQ F + V C G V D TH K MHPT+
Sbjct: 6 QGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIK--PMHPTS 63
Query: 62 EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY 121
GV+DM L +L+ I+ NL RY+ + IYTY GSIL +VNPYQ + +Y P + QY
Sbjct: 64 VHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQ-LLSIYSPEHIRQY 122
Query: 122 SRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQS 181
+ + +GE+PPHIFAIA+ CY + + +QC +ISGESGAGKTESTKLIL+FL+ IS Q
Sbjct: 123 TNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQH 182
Query: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
S +E+ +LE++PI+EAFGNAKT+ N+NSSRFGK++ ++ ++G I+G +I
Sbjct: 183 ---------SWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIE 233
Query: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTIS 301
YLLEK+RV RQ ERNYH+FY +L G+ +++++ L +Y+YL C+ +
Sbjct: 234 QYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRV 293
Query: 302 DQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIE-----FITAGGAQVSFKTALG 356
D + + + +AM V+ F+ E E+S+LLA ILHLGN++ F +V F +L
Sbjct: 294 DSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLA 353
Query: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
+A LL ++P L LT R++ RGE + TPL+ +QA+D RD+ +Y F W++ K
Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDK 413
Query: 417 INSRI--KGNEDFK----SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLE 470
IN+ I ++D K SIG+LDIFGFENF VN FEQ IN+ANE LQ++F +H+F LE
Sbjct: 414 INAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLE 473
Query: 471 QLEYSREGLVWEDIDWIDNGECLDLI-EKKLGLLALINEESHFPQATDSTLLEKLHSQHA 529
Q EY E + W I++ DN + LD+I K + +++LI+EES FP+ TD+T+L KL+SQH
Sbjct: 474 QEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHK 533
Query: 530 NNHFYVKPRVAVNN----FGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIY 585
N Y+ P+ NN FG+ H+AG V Y+ +G LEKNRDT D++ L+ SR FI
Sbjct: 534 LNANYIPPK---NNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIK 590
Query: 586 DLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMP 645
+F+ + ++ R PT+SSQFK SL LM TL + PFFVRCIKPN K P
Sbjct: 591 QIFQ------ADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKP 644
Query: 646 DQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLA---LPEDVRGK 702
FD+ + + QLRYSGM+ET+RIR+AGY +R F +F +RY+VL+ + D+RG
Sbjct: 645 MLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGT 704
Query: 703 CTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQY 762
C + + ++ +WQ+GKTK+FL++ + LE R++ ++ ++++ + GF R +
Sbjct: 705 CQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNF 764
Query: 763 RKVLYCVVIIQ---------KNY------------------------------------- 776
K+ +IQ KNY
Sbjct: 765 LKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARC 824
Query: 777 RAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK--REQEEKKKQEEEEKKKRE- 833
RA+L+R+ F H A + Q RG IARR++++L AE R + EK + EEEK ++E
Sbjct: 825 RAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEM 884
Query: 834 -----EEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
+EE ER+ + R A+L + E +EL+ + ++++ EL ++E+ +
Sbjct: 885 SAKKAKEEAERKHQERLAQLAREDAE-----RELKEKEAARRKKELLEQMERAR 933
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 651 bits (1679), Expect = 0.0
Identities = 376/954 (39%), Positives = 557/954 (58%), Gaps = 104/954 (10%)
Query: 7 EGTRVWLREN-GQHFP----STVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTN 61
+G VW+ GQ F + V C G V D TH K MHPT+
Sbjct: 6 QGDHVWMDLRLGQEFDVPIGAVVKLCDSGQVQVVDDEDNEHWISPQNATHIK--PMHPTS 63
Query: 62 EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY 121
GV+DM L +L+ I+ NL RY+ + IYTY GSIL +VNPYQ + +Y P + QY
Sbjct: 64 VHGVEDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQ-LLSIYSPEHIRQY 122
Query: 122 SRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQS 181
+ + +GE+PPHIFAIA+ CY + + +QC +ISGESGAGKTESTKLIL+FL+ IS Q
Sbjct: 123 TNKKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISGQH 182
Query: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
S +E+ +LE++PI+EAFGNAKT+ N+NSSRFGK++ ++ ++G I+G +I
Sbjct: 183 ---------SWIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIE 233
Query: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTIS 301
YLLEK+RV RQ ERNYH+FY +L G+ +++++ L +Y+YL C+ +
Sbjct: 234 QYLLEKSRVCRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRV 293
Query: 302 DQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIE-----FITAGGAQVSFKTALG 356
D + + + +AM V+ F+ E E+S+LLA ILHLGN++ F +V F +L
Sbjct: 294 DSQEYANIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLA 353
Query: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
+A LL ++P L LT R++ RGE + TPL+ +QA+D RD+ +Y F W++ K
Sbjct: 354 TAASLLEVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDK 413
Query: 417 INSRI--KGNEDFK----SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLE 470
IN+ I ++D K SIG+LDIFGFENF VN FEQ IN+ANE LQ++F +H+F LE
Sbjct: 414 INAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLE 473
Query: 471 QLEYSREGLVWEDIDWIDNGECLDLI-EKKLGLLALINEESHFPQATDSTLLEKLHSQHA 529
Q EY E + W I++ DN + LD+I K + +++LI+EES FP+ TD+T+L KL+SQH
Sbjct: 474 QEEYDLESIDWLHIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHK 533
Query: 530 NNHFYVKPRVAVNN----FGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIY 585
N Y+ P+ NN FG+ H+AG V Y+ +G LEKNRDT D++ L+ SR FI
Sbjct: 534 LNANYIPPK---NNHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIK 590
Query: 586 DLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMP 645
+F+ + ++ R PT+SSQFK SL LM TL + PFFVRCIKPN K P
Sbjct: 591 QIFQ------ADVAMGAETRKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKP 644
Query: 646 DQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLA---LPEDVRGK 702
FD+ + + QLRYSGM+ET+RIR+AGY +R F +F +RY+VL+ + D+RG
Sbjct: 645 MLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGT 704
Query: 703 CTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQY 762
C + + ++ +WQ+GKTK+FL++ + LE R++ ++ ++++ + GF R +
Sbjct: 705 CQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNF 764
Query: 763 RKVLYCVVIIQ---------KNY------------------------------------- 776
K+ +IQ KNY
Sbjct: 765 LKLKNAATLIQRHWRGHNCRKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARC 824
Query: 777 RAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK--REQEEKKKQEEEEKKKRE- 833
RA+L+R+ F H A + Q RG IARR++++L AE R + EK + EEEK ++E
Sbjct: 825 RAYLVRKAFRHRLWAVLTVQAYARGMIARRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEM 884
Query: 834 -----EEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
+EE ER+ + R A+L + E +EL+ + ++++ EL ++E+ +
Sbjct: 885 SAKKAKEEAERKHQERLAQLAREDAE-----RELKEKEAARRKKELLEQMERAR 933
Score = 60.8 bits (146), Expect = 1e-08
Identities = 66/251 (26%), Positives = 109/251 (43%), Gaps = 20/251 (7%)
Query: 1599 LRP-LRDELYCQLIKQTNKVPHPGSVGNLYSWQILT-CLSCTFLPSRGILKYLKFHLKRI 1656
LRP LRDE+YCQ+ KQ P S W +++ C+ C F PS +KYL+ I
Sbjct: 1163 LRPALRDEIYCQISKQLTHNPSKSSYAR--GWILVSLCVGC-FAPSEKFVKYLR---NFI 1216
Query: 1657 REQFPGSEMEKYALFTYESLKKT---KCREFVPSRDEIEALIHRQEMTSTVYCHGGGSCK 1713
PG YA + E L++T R PS E++A ++ + V G +
Sbjct: 1217 HGGPPG-----YAPYCEERLRRTFVNGTRTQPPSWLELQATKSKKPIMLPVTFMDGTTKT 1271
Query: 1714 ITINSHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAA 1773
+ +S TTA E+ L ++++D V V D +++ E+ A
Sbjct: 1272 LLTDSATTAKELCNALADKISLKDRFGFSLYIALFDKVSSLGSGSDHVMDAISQCEQYAK 1331
Query: 1774 T--SEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPEENLQVLA 1831
++ + PW+ +F+ F + +D+V +++Q V G + +E+ LA
Sbjct: 1332 EQGAQERNAPWRLFFRKEVFTPWHSPSEDNVATNLIYQQVVRGVKFGEYRCEKED--DLA 1389
Query: 1832 ALRLQYLQGDY 1842
L Q DY
Sbjct: 1390 ELASQQYFVDY 1400
Score = 55.8 bits (133), Expect = 4e-07
Identities = 101/458 (22%), Positives = 178/458 (38%), Gaps = 80/458 (17%)
Query: 1601 PLRDELYCQLIKQT--NKVPHPGSVGNLYSWQILTCLSCTFLPSRGILKYLKFHLKRIRE 1658
PL+DE Y Q++KQ N + + G W++L + F PS +L H++R +
Sbjct: 1808 PLKDEAYVQILKQLTDNHIRYSEERG----WELLWLCTGLFPPSNILLP----HVQRFLQ 1859
Query: 1659 QFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHRQ-EMTSTVYCHGGGSCKITIN 1717
+ L + + R++ P E+EA+ H+ ++ VY +
Sbjct: 1860 SRKHCPLAIDCLQRLQKALRNGSRKYPPHLVEVEAIQHKTTQIFHKVYFPDDTDEAFEVE 1919
Query: 1718 SHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADV---LAKFEKLAAT 1774
S T A + + + L ++ S F+LF ++ D L + K A
Sbjct: 1920 SSTKAKDFCQNIATRLLLKSSEG-FSLFVKIADKVLSVPENDFFFDFVRHLTDWIKKARP 1978
Query: 1775 SEVGDLPWKFYFKLYCF-LDTDNVP-KDSV-EFAFMFEQAHEAVIHGHHPAPEENLQVLA 1831
+ G +P Y + L T VP KD + + F + Q + G+H E + L
Sbjct: 1979 IKDGIVPSLTYQVFFMKKLWTTTVPGKDPMADSIFHYYQELPKYLRGYHKCTREEVLQLG 2038
Query: 1832 AL--RLQYLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKTFTPCERLEKRRTSFLEGTL 1889
AL R+++ + D + +IP L Q L ++S
Sbjct: 2039 ALIYRVKF-EEDKSYFPSIPKLLRELVPQDLIRQVSP----------------------- 2074
Query: 1890 RRSFRTGSVVRQKVEEEQMLDMWIKEEVSSARASIIDKWRKFQGMNQEQAMAKYMALIKE 1949
D W + SI+ + K G ++E+A ++ LI +
Sbjct: 2075 --------------------DDW--------KRSIVAYFNKHAGKSKEEAKLAFLKLIFK 2106
Query: 1950 WPGYGSTLFDV-ECKEGGFPQELWLGVSADAVSVYKRGEGRPLEVFQYEHILSFGAPLAN 2008
WP +GS F+V + E FP+ L + ++ VS+ L + I ++ + N
Sbjct: 2107 WPTFGSAFFEVKQTTEPNFPEILLIAINKYGVSLIDPKTKDILTTHPFTKISNWSS--GN 2164
Query: 2009 TYKIV-----VDERELLFETSEVVDVAKLMKAYISMIV 2041
TY + V +LL ETS + L+ +YIS ++
Sbjct: 2165 TYFHITIGNLVRGSKLLCETSLGYKMDDLLTSYISQML 2202
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 599 bits (1545), Expect = e-171
Identities = 333/841 (39%), Positives = 497/841 (59%), Gaps = 46/841 (5%)
Query: 5 FTEGTRVWLRENGQH-----FPSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHP 59
F G VWL H + G V+ D G+ + ++ MHP
Sbjct: 4 FRLGDHVWLEPPSTHKTGVAIGGIIKEAKPGKVLVEDDEGKEHWIRAEDFG--VLSPMHP 61
Query: 60 TNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATME 119
+ +GVDDM L +L+ +++NL RY++++IYTY GSIL +VNP+Q + LY ++
Sbjct: 62 NSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQ-VLPLYTLEQVQ 120
Query: 120 QYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ 179
Y RH+GELPPH+FAIAN CY + + +QC +ISGESGAGKTE+TKLIL+FL+ IS
Sbjct: 121 LYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATISG 180
Query: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
Q S +E+ +LE++PI+EAFGNAKT+ N+NSSRFGK++ + G I+G R
Sbjct: 181 QH---------SWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGAR 231
Query: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKT 299
I +LLEK+RV RQ P ERNYHIFY +L G+ E+++ L TP YHYL C +
Sbjct: 232 IEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEG 291
Query: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITA-----GGAQVSFKTA 354
++D + + + +AM ++QFS E +V +LLA ILHLGN+ F+ + + V A
Sbjct: 292 LNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPA 351
Query: 355 LGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVI 414
+LL + +L D L + ++ +RGE + LN+ QA D RD+ +Y F W++
Sbjct: 352 FPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIV 411
Query: 415 KKINSRI------KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFS 468
KKIN+ I ++IG+LDIFGFENFE N FEQ IN+ANE LQ++F +H+F+
Sbjct: 412 KKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFT 471
Query: 469 LEQLEYSREGLVWEDIDWIDNGECLDLIE-KKLGLLALINEESHFPQATDSTLLEKLHSQ 527
+EQ EY E + W+ I + DN LDL+ K + +++L++EES FPQ TD T+L+KL+S
Sbjct: 472 MEQEEYRSENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSV 531
Query: 528 HANNHFYVKPR-VAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYD 586
HANN +++P+ + FG+ H+AGEV Y G LEKNRD D+L L+ S+ F+ +
Sbjct: 532 HANNKAFLQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLRE 591
Query: 587 LF--EHVSSRNNQDTL----------KCGSKHRRP-TVSSQFKDSLHSLMATLSSSNPFF 633
+F E ++ T+ K ++RP T+ SQFK SL LM L++ P+F
Sbjct: 592 IFNLELAETKLGHGTIRQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYF 651
Query: 634 VRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRN- 692
+RCIKPN K P FD+ + L QLRYSGM+ETV IRK+G+ +R F++F +R+ VL+ N
Sbjct: 652 IRCIKPNEYKKPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNA 711
Query: 693 --LALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIR 750
+ L +R + ++ ++ +W+ GKTK+FLR+ + LE +R + + AA+ I+
Sbjct: 712 MRMQLQGKLRQMTLGITDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQ 771
Query: 751 AHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQ 810
+ G+ RK++ + V +Q +R + RR F + Q R Q R Y+
Sbjct: 772 KVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQA 831
Query: 811 L 811
+
Sbjct: 832 M 832
Score = 60.1 bits (144), Expect = 2e-08
Identities = 64/250 (25%), Positives = 104/250 (41%), Gaps = 22/250 (8%)
Query: 1599 LRP-LRDELYCQLIKQTNKVPHPGSVGNLYSWQILT-CLSCTFLPSRGILKYLKFHLKRI 1656
LRP LRDE+YCQ+ KQ ++ S+ W +L+ CL C F PS +KYL
Sbjct: 1102 LRPSLRDEIYCQICKQLSENFKTSSLAR--GWILLSLCLGC-FPPSERFMKYLL------ 1152
Query: 1657 REQFPGSEMEKYALFTYESLKKTKC---REFVPSRDEIEALIHRQEMTSTVYCHGGGSCK 1713
F G Y F E L++T R P+ E++A+ ++ + V G S
Sbjct: 1153 --NFIGQGPATYGPFCAERLRRTYANGVRAEPPTWLELQAVKSKKHIPIQVILATGESLT 1210
Query: 1714 ITINSHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHVDKAIESRTVVADVLAKFEKLAA 1773
+ ++S +T+ E+ + + D R + D +A+ E++A
Sbjct: 1211 VPVDSASTSREMCMHIAHKQGLSDHLGFSLQVAVYDKFWSLGSGRDHMMDAIARCEQMA- 1269
Query: 1774 TSEVGD----LPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIHGHHPAPEENLQV 1829
E G+ PW+ YF+ F + +D V ++ Q V G + +E V
Sbjct: 1270 -QERGESQRQSPWRIYFRKEFFTPWHDSREDPVSTELIYRQVLRGVWSGEYSFEKEEELV 1328
Query: 1830 LAALRLQYLQ 1839
R Y+Q
Sbjct: 1329 ELLARHCYVQ 1338
Score = 44.7 bits (104), Expect = 0.001
Identities = 102/537 (18%), Positives = 193/537 (35%), Gaps = 99/537 (18%)
Query: 1529 RNPILRYTHHPLHSPLLPLPYGDINLNLLKDKGYTTLQDEAIKIFNSLQQLESMSD---- 1584
R + Y+ PL PLL + +++L D A +IF ++ L M D
Sbjct: 1638 RGHLWAYSCEPLRQPLLKRVHANVDL-----------WDIACQIFVAI--LRYMGDYPSR 1684
Query: 1585 ----PIPIIQGILQTGHDLRPLRDELYCQLIKQT--NKVPHPGSVGNLYSWQILTCLSCT 1638
+ + I L+DE+YCQ++KQ N H G WQ+L +
Sbjct: 1685 QAWPTLELTDQIFTLALQHPALQDEVYCQILKQLTHNSNRHSEERG----WQLLWLCTGL 1740
Query: 1639 FLPSRGILKYLKFHLKRIREQFPGSEMEKYALFTYESLKKTKCREFVPSRDEIEALIHR- 1697
F PS+G+L H ++ + G + + + +T R+ P + E+EA
Sbjct: 1741 FPPSKGLLP----HAQKFIDTRRGKLLAPDCSRRIQKVLRTGPRKQPPHQVEVEAAEQNV 1796
Query: 1698 QEMTSTVYCHGGGSCKITINSHTTAGEVVEKLIRGLAMEDSRNMFALFEYNGHV------ 1751
+ +Y S + + ++T +V + + L + + + V
Sbjct: 1797 SRICHKIYFPNDTSEMLEVVANTRVRDVCDSIATRLQLASWEGCSLFIKISDKVISQKEG 1856
Query: 1752 DKAIESRTVVADVLAKFEKLAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQA 1811
D +S V+D + K + + V LP++ YF +L+ + + + Q
Sbjct: 1857 DFFFDSLREVSDWVKKNKPQKEGAPV-TLPYQVYFMRKLWLNISPGKDVNADTILHYHQE 1915
Query: 1812 HEAVIHGHHPAPEENLQVLAALRLQ-YLQGDYTLHAAIPPLEEVYSLQRLKARISQSTKT 1870
+ G H E+ LA L + D + A++P
Sbjct: 1916 LPKYLRGFHKCSREDAIHLAGLIYKAQFNNDRSQLASVP--------------------- 1954
Query: 1871 FTPCERLEKRRTSFLEGTLRRSFRTGSVVRQKVEEEQMLDMWIKEEVSSARASIIDKWRK 1930
++R+ V E M +E + SI+ + K
Sbjct: 1955 --------------------------KILRELVPENLTRLMSSEE----WKKSILLAYDK 1984
Query: 1931 FQGMNQEQAMAKYMALIKEWPGYGSTLFDV-ECKEGGFPQELWLGVSADAVSVYKRGEGR 1989
+ E+A ++ I WP +GS F+V + E +P + + ++ V +
Sbjct: 1985 HKDKTVEEAKVAFLKWICRWPTFGSAFFEVKQTSEPSYPDVILIAINRHGVLLIHPKTKD 2044
Query: 1990 PLEVFQYEHILSFGAPLANTYKIVV-----DERELLFETSEVVDVAKLMKAYISMIV 2041
L + + I S+ + +TY + LL ETS + L+ +Y+ ++
Sbjct: 2045 LLTTYPFTKISSWSS--GSTYFHMALGSLGRGSRLLCETSLGYKMDDLLTSYVQQLL 2099
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 594 bits (1532), Expect = e-169
Identities = 339/787 (43%), Positives = 487/787 (61%), Gaps = 28/787 (3%)
Query: 62 EEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY 121
E+GV+DM L +L +++ NL R++RN IYTYIGSIL SVNPYQ + G+Y P ++QY
Sbjct: 1221 EDGVEDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQ-MFGIYGPEQVQQY 1279
Query: 122 SRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQS 181
+ R LGE PPH+FA+AN + + NQCI+ISGESG+GKTE+TKLIL++L+ ++Q+
Sbjct: 1280 NGRALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKR 1339
Query: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
+ + ILE++P++E+FGNAKTV N+NSSRFGKFV++ + + G I G
Sbjct: 1340 EVMQ--------QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEIFL-EGGVISGAITS 1390
Query: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTIS 301
YLLEK+R+V Q ERNYHIFY LLAGL + R+ F L E Y+YLNQ G E S
Sbjct: 1391 QYLLEKSRIVFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKS 1450
Query: 302 DQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFI-----TAGGAQVSFKTALG 356
D + FR ++ AM+V+ FS E+ + R+LA ILHLGN+ F A V +
Sbjct: 1451 DADDFRRLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQ 1510
Query: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
AELL + P L A+T + E+I TPL V+ AVD+RD++A LYA F W+I +
Sbjct: 1511 AVAELLQISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITR 1570
Query: 417 INSRIKGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSR 476
+N+ + +D SI ILDI+GFE+ N FEQ INYANE LQ FNK +F EQ EY R
Sbjct: 1571 VNALVSPRQDTLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIR 1630
Query: 477 EGLVWEDIDWIDNGECLDLIE-KKLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYV 535
E + W++I + DN C++LI K G+L +++++ FPQATD T L+K H H N Y
Sbjct: 1631 EQIDWQEITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYS 1690
Query: 536 KPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFE-HVSSR 594
KP++ + F +KHYAG+V Y V L+KN D R D+L+L SR + LF H
Sbjct: 1691 KPKMPLPEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHLFSSHAPQA 1750
Query: 595 NNQDTLKCGSK---HRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQA 651
Q K S ++ TV+++F+ SL L+ + NP F+RC+KPN +K P F+
Sbjct: 1751 APQRLGKSSSVTRLYKAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPD 1810
Query: 652 VVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDVRGK---CTSLL- 707
VV+ QLRYSG+LETVRIRK G+ VR PFQ F RY L+ AL D+ C S+L
Sbjct: 1811 VVMAQLRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLV---ALKHDLPANGDMCVSVLS 1867
Query: 708 QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY 767
+L + +++G +K+FL+E L Q LE RE ++ AA+ ++ + GF ++++R + +
Sbjct: 1868 RLCKVMPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRH 1927
Query: 768 CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQ-EEKKKQEE 826
++++Q R +L R+R+ ++++ + F+ + ++RR Y +L AE R Q E E+
Sbjct: 1928 KIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQVEGALLWEQ 1987
Query: 827 EEKKKRE 833
EE KRE
Sbjct: 1988 EELSKRE 1994
Score = 46.6 bits (109), Expect = 3e-04
Identities = 76/337 (22%), Positives = 139/337 (41%), Gaps = 33/337 (9%)
Query: 1532 ILRYTHHPLHSPLLPLPYGDINLNLLKDKGYTTLQDEAIKIFNSLQQLESMSDPIPIIQG 1591
+L +T PL L+ L D +L+ + + A+ F L+ SD + ++
Sbjct: 3047 MLCFTKTPLQESLIEL--SDSSLSKMATDMFL-----AVMRFMGDAPLKGQSD-LDVLCN 3098
Query: 1592 ILQTGHDLRPLRDELYCQLIKQTNKVPHPGSVGNLYSWQILTCLSCTFLPSRGILKYLKF 1651
+L+ D +RDE YCQ++KQ W++L ++ S + +L
Sbjct: 3099 LLKLCGDHEVMRDECYCQVVKQITDNTSSKQDSCQRGWRLLYIVTAYHSCSEVLHPHLTR 3158
Query: 1652 HLKRIREQFPGSEMEKYALFTYESLKKT---KCREFVPSRDEIEALI-HRQEMTSTVYCH 1707
L+ + + PG + A ++L+KT R +PS E+ A++ R
Sbjct: 3159 FLQDV-SRTPGLPFQGIAKACEQNLQKTLRFGGRLELPSSIELRAMLAGRSSKRQLFLLP 3217
Query: 1708 GGGSCKITINSHTTAGEVVEKLIRGLAM--EDSRNMFALF--EYNGHVDKAIESRTVVAD 1763
GG + I + T A +VVE++ +A+ ++ N + +F G + R + D
Sbjct: 3218 GGLERHLKIKTCTVALDVVEEICAEMALTRPEAFNEYVIFVVTNRGQHVCPLSRRAYILD 3277
Query: 1764 VLAKFEK------LAATSEVGDLPWKFYFKLYCFLDTDNVPKDSVEFAFMFEQAHEAVIH 1817
V ++ E+ L + D P KF +LY + + V D ++ F + +
Sbjct: 3278 VASEMEQVDGGYMLWFRRVLWDQPLKFENELYVTMHYNQVLPDYLKGLF-------SSVP 3330
Query: 1818 GHHPAPEENLQVLAALRLQYLQGDYTLHAAIPPLEEV 1854
P+ + QV LQ+ D H +P + EV
Sbjct: 3331 ASRPSEQLLQQVSKLASLQHRAKD---HFYLPSVREV 3364
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 555 bits (1431), Expect = e-157
Identities = 341/999 (34%), Positives = 546/999 (54%), Gaps = 75/999 (7%)
Query: 5 FTEGTRVWLRENGQHFPST--VNSCAEG--IVVFRTDYGQVFTYKQSTITHQKVTAMHPT 60
+++ TRVW+ + + + S EG + R + + Y +Q +P
Sbjct: 7 YSQCTRVWIPDPDEVWRSAELTKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLRNPD 66
Query: 61 NEEGVDDMASLTELHGGSIMYNLFQRY-KRNQIYTYIGSILASVNPYQPIAGLYEPATME 119
G +D+ +L+ LH ++++NL R+ + N IYTY G +L ++NPY+ + +Y +
Sbjct: 67 ILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLP-IYGQDVIY 125
Query: 120 QYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ 179
YS +++G++ PHIFA+A E Y+ + + NQ I++SGESGAGKT S K +++ + +
Sbjct: 126 TYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGG 185
Query: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
+ E +++EK +L SSPIMEA GNAKT N+NSSRFGK++Q+ ++ +I G
Sbjct: 186 SASETNIEEK-------VLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGAN 238
Query: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKT 299
+ YLLEK+RVV Q ERNYHIFY L A E +E L++ E++ Y +Q G +
Sbjct: 239 MRTYLLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEG 298
Query: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF-ITAGGAQVSFKTA---L 355
+ D E F + A ++ + + +++A ILHLG++ G S L
Sbjct: 299 VDDAEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYL 358
Query: 356 GRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIK 415
LLG++ +Q+ L R + E + +++QQ +++R++LA +YA F W+++
Sbjct: 359 SNFCRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVE 418
Query: 416 KINSRIKGN-EDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEY 474
IN + + + IG+LDI+GFE FEVN FEQF INYANEKLQ+ FN H+F LEQ EY
Sbjct: 419 HINKALHTSLKQHSFIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEY 478
Query: 475 SREGLVWEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANNHFY 534
+E + W ID+ DN C+DLIE KLG+L L++EE P+ TD +KL+ +H+++ +
Sbjct: 479 MKEQIPWTLIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHF 538
Query: 535 VKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF------ 588
KPR++ F + H+A +V+Y G LEKNRDT ++ +N+L+ S+F + DLF
Sbjct: 539 QKPRMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDP 598
Query: 589 -----------EHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCI 637
+S R+ + +K +K + TV QF+ SLH LM TL+++ P +VRCI
Sbjct: 599 VPATTPGKGSSSKISVRSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCI 658
Query: 638 KPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE 697
KPN +K+P FD + QLR G+LET+RI AGY R + DF+ RY+VL++ L
Sbjct: 659 KPNDEKLPFHFDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELAN 718
Query: 698 -DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGF 756
D + C S+L+ ++Q G+TK+F R LEK R ++ A ++I+ V G+
Sbjct: 719 TDKKAICRSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGW 778
Query: 757 LARKQYRKV--------LYC-----------------VVIIQKNYRAFLLRRRFLHLKKA 791
L + +Y ++ YC V++QK+YR R+ + +++A
Sbjct: 779 LQKVKYHRLKGATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRA 838
Query: 792 AIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQ 851
A+V Q R RR YRQ+L E K +K R R + R+A + Q
Sbjct: 839 AVVIQAFTRAMFVRRTYRQVLME-------HKATTIQKHVRGWMARRHFQRLRDAAIVIQ 891
Query: 852 QEEETRK-QQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELS 910
K ++EL+AL+ + AE + L ENK V+ +++++ ++ + + EQ LS
Sbjct: 892 CAFRMLKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQ--LS 949
Query: 911 LTEASLQKLQERRDQELRRLE----EEACRAAQEFLESL 945
+T ++ ER +EL + E+ QE +ESL
Sbjct: 950 VTTSTYTMEVERLKKELVHYQQSPGEDTSLRLQEEVESL 988
Score = 67.4 bits (163), Expect = 1e-10
Identities = 87/350 (24%), Positives = 153/350 (43%), Gaps = 57/350 (16%)
Query: 635 RCIKPNMQKMPD--QFDQAVVL---NQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVL 689
R + N+ K PD QF + + Q+ Y L + R A +++ + + ++ K
Sbjct: 726 RSVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKY- 784
Query: 690 MRNLALPEDVRGKCTSLLQLYDASNSEWQLG------KTKVFLRESLEQKLEKRREEEVS 743
++G T LQ Y + +L + V L++ + ++ + V
Sbjct: 785 -------HRLKG-ATLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVR 836
Query: 744 HAAMVIRAHVLGFLARKQYRKVL--YCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG 801
AA+VI+A R+ YR+VL + IQK+ R ++ RR F L+ AAIV Q R
Sbjct: 837 RAAVVIQAFTRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRM 896
Query: 802 QIARRVYRQLLAEKREQEEKKK-------QEEEEKKKREEEERE---------------- 838
ARR + L E R E K+ + + ++K +E+ +E
Sbjct: 897 LKARRELKALRIEARSAEHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956
Query: 839 RERERREAELRAQQE---EET--RKQQELEALQKSQKEAELTRELEKQKENKQVEEILR- 892
E ER + EL Q+ E+T R Q+E+E+L+ + A R++ + +++ +E+ +
Sbjct: 957 MEVERLKKELVHYQQSPGEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKR 1016
Query: 893 ---LEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE---LRRLEEEACR 936
LE+E L+ KEQ + S + + +E + LEEE R
Sbjct: 1017 VADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSR 1066
Score = 41.6 bits (96), Expect = 0.008
Identities = 42/163 (25%), Positives = 84/163 (51%), Gaps = 15/163 (9%)
Query: 802 QIARRVYRQLLAEKREQEEKKKQEEEEKKK-REEEERERERERREAELRAQQEEETRKQQ 860
Q+AR + QL A+ E EE+ + + + + +EE +++++ + L + + E QQ
Sbjct: 1338 QVARLLEAQLQAQSLEHEEEVEHLKAQLEALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQ 1397
Query: 861 ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ 920
E+ L + + +L +EK ++N++ +L+K+++ MK+ Q+L +A Q
Sbjct: 1398 EISRL--TNENLDLKELVEKLEKNER-----KLKKQLKIY--MKKAQDLEAAQALAQ--S 1446
Query: 921 ERRDQELRRLEEEACRAAQEFLESLNFDEIDEC--VRNIERSL 961
ER+ EL R + R ++F L + + DE +RN+ L
Sbjct: 1447 ERKRHELNR-QVTVQRKEKDFQGMLEYHKEDEALLIRNLVTDL 1488
Score = 36.2 bits (82), Expect = 0.34
Identities = 48/230 (20%), Positives = 90/230 (39%), Gaps = 71/230 (30%)
Query: 738 REEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFL----------H 787
R+ + H A I+ HV G++AR+ ++++ ++IQ +R RR H
Sbjct: 856 RQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKALRIEARSAEH 915
Query: 788 LKKAAIVFQKQLRGQIARRVYRQ-----LLAEK---------REQEEKKKQ--------- 824
LK+ + + ++ Q+ R++ Q L+E+ E E KK+
Sbjct: 916 LKRLNVGMENKVV-QLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSPG 974
Query: 825 -------EEEEKKKREEEERERERERREAELRAQQEEETRK------------------- 858
+EE + R E +R + + +++++E RK
Sbjct: 975 EDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQL 1034
Query: 859 ------QQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQR 902
Q + E Q S KE + +ELE+++ Q L KE L++
Sbjct: 1035 NNQILCQSKDEFAQNSVKENLMKKELEEERSRYQ-----NLVKEYSQLEQ 1079
Score = 33.1 bits (74), Expect = 2.9
Identities = 32/142 (22%), Positives = 64/142 (45%), Gaps = 7/142 (4%)
Query: 798 QLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR 857
Q + + A+ ++ L +K +EE+ + + K+ + E+R + R E + Q R
Sbjct: 1041 QSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQR-YDNLRDEMTIIKQTPGHRR 1099
Query: 858 KQQELEALQKSQKEAEL-TRELEKQKENKQVEEILRLEKEIED----LQRMKEQQELSLT 912
+L+ + T E+ ++ Q E + LEK D L+ K +EL
Sbjct: 1100 NPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLKLQKRVRELEQE 1159
Query: 913 EASLQ-KLQERRDQELRRLEEE 933
LQ +L++R Q+ ++++ E
Sbjct: 1160 RKKLQVQLEKREQQDSKKVQAE 1181
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 548 bits (1412), Expect = e-155
Identities = 326/975 (33%), Positives = 542/975 (55%), Gaps = 86/975 (8%)
Query: 64 GVDDMASLTELHGGSIMYNLFQRYKRNQ-IYTYIGSILASVNPYQPIAGLYEPATMEQYS 122
G +D+ +L+ LH ++++NL R+ ++ IYTY G IL ++NPY+ + +Y A + YS
Sbjct: 68 GENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLP-IYGDAIIHAYS 126
Query: 123 RRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSL 182
+++G++ PHIFA+A E Y+ + + + NQ I++SGESGAGKT S + +++ + +S+
Sbjct: 127 GQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGS 186
Query: 183 ELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVD 242
+++K +L S+PI EA GNAKT N+NSSRFGK+ +++ ++ I G +
Sbjct: 187 NAHVEDK-------VLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMST 239
Query: 243 YLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISD 302
YLLEK+RVV Q+ ERNYHIFY L A + E + L + E ++Y G + ++D
Sbjct: 240 YLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVND 299
Query: 303 QESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFK---TALGRSA 359
+ E ++ F ++ +V ++LA ILHLGN++ G + S + L
Sbjct: 300 RAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNERSSVSEDDSHLKVFC 359
Query: 360 ELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINS 419
ELLGL+ ++ L R + E ++ P+ QAV++RD+LA +YA F++++++IN
Sbjct: 360 ELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQ 419
Query: 420 RIK-GNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREG 478
++ + IG+LDI+GFE F+VN FEQF INYANEKLQ+ FN H+F LEQ EY +E
Sbjct: 420 ALQFSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKED 479
Query: 479 LVWEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHAN-NHFYVKP 537
+ W ID+ DN +DLIE K+G+L L++EE P TD L+KL++ N N + KP
Sbjct: 480 IPWTLIDFYDNQPVIDLIEAKMGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKP 539
Query: 538 RVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEH------- 590
R++ +F ++H+A +V+Y G LEKNRDT D L+ +LR S+F + F+
Sbjct: 540 RMSNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSP 599
Query: 591 ----VSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPD 646
++ ++ + +K SKH R TV S+F+ SL+ LM TL+++ P +VRCIKPN +K+P
Sbjct: 600 FGSMITVKSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPF 659
Query: 647 QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALP-EDVRGKCTS 705
+FD ++ QLR G+LET+RI Y R + +FY RY +LM L D + C
Sbjct: 660 EFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKV 719
Query: 706 LLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQY--- 762
+L ++++Q GKTK+F R LEK R +++ + ++++ H+ G+L RK++
Sbjct: 720 VLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRE 779
Query: 763 -----------------RKVL--------YCVVIIQKNYRAFLLRRRFLHLKKAAIVFQK 797
RK + + +IIQK+ R +L+R + ++ A I Q
Sbjct: 780 RRAALIIQQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQA 839
Query: 798 QLRGQIARRVYRQL----------------LAEKREQEEKK---------KQEEEEKKKR 832
RG +ARR YR++ LA +R Q ++ + + +KK
Sbjct: 840 YSRGFLARRRYRKMLEEHKAVILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLE 899
Query: 833 EEEERERERERREAELRAQQEEETRKQQELEA-LQKSQKEAELTRELEKQKENKQVEEIL 891
++ + + L A + + K Q+LEA L+K+ E K+ + E++
Sbjct: 900 DQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLA 959
Query: 892 RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRL-----EEEACRAAQEFLESLN 946
+L+K +L+ KEQ +L L E + ++L+E+ D ++L +EE R E L
Sbjct: 960 KLQKHNSELETQKEQIQLKLQEKT-EELKEKMDNLTKQLFDDVQKEERQRMLLEKSFELK 1018
Query: 947 FDEIDECVRNIERSL 961
+ ++ +++++ +
Sbjct: 1019 TQDYEKQIQSLKEEI 1033
Score = 55.5 bits (132), Expect = 5e-07
Identities = 83/382 (21%), Positives = 160/382 (41%), Gaps = 93/382 (24%)
Query: 656 QLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRN---LALPEDVRGKCTSLLQLYDA 712
Q+ Y L ++R++ V++ + + +R K L L + + RG+ T +
Sbjct: 744 QVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKAITAV 803
Query: 713 SNSE-WQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVL--YCV 769
+ E W + +++ L + + + A + ++A+ GFLAR++YRK+L +
Sbjct: 804 ALKEAW----AAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKA 859
Query: 770 VIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVY--------------------- 808
VI+QK RA+L RRRF +++ + Q R Q ++
Sbjct: 860 VILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALR 919
Query: 809 -------RQLLAE-------KREQEEKKKQEE---EEK-----KKREEEERERER----- 841
++L AE +R EEK K+ EEK K E E ++E+
Sbjct: 920 AGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDAVEEKLAKLQKHNSELETQKEQIQLKL 979
Query: 842 ERREAELRAQQEEETRKQQELEALQKSQKE---AELTRELEKQKENKQV----EEILRLE 894
+ + EL+ + + T+ Q + +QK +++ E + EL+ Q KQ+ EEI L+
Sbjct: 980 QEKTEELKEKMDNLTK--QLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALK 1037
Query: 895 KEIEDLQRMKE--------------------------QQELSLTEASLQKLQERRDQELR 928
E LQ + E ++E+ L +A +++ + R
Sbjct: 1038 DEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEKHVQSQKR 1097
Query: 929 RLEEEACRAAQEFLESLNFDEI 950
+ E+ ++ LES + +++
Sbjct: 1098 EMREKMSEITKQLLESYDIEDV 1119
Score = 42.0 bits (97), Expect = 0.006
Identities = 44/207 (21%), Positives = 96/207 (46%), Gaps = 24/207 (11%)
Query: 740 EEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQ- 798
E + A V+ +H Q +K Y I N++ L + HL+K +F+++
Sbjct: 1142 EGLKKATRVLESHF-------QSQKDCYEKEIEALNFKVVHLSQEINHLQK---LFREEN 1191
Query: 799 -----LRGQIARRVYRQLLAEKREQE----EKKKQEEEEKKKREEEERERERERREAELR 849
+R ++ R ++ +Q+ EK+KQ+ E + + E+ + + E +L
Sbjct: 1192 DINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLH 1251
Query: 850 AQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQE- 908
QEEE Q++ Q E + ++K +E ++ + L+ + E E + +QE
Sbjct: 1252 RSQEEE-GTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310
Query: 909 --LSLTEASLQKLQERRDQELRRLEEE 933
L+L L++ + +D+ +++L+++
Sbjct: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQ 1337
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 531 bits (1369), Expect = e-150
Identities = 339/1063 (31%), Positives = 554/1063 (52%), Gaps = 115/1063 (10%)
Query: 5 FTEGTRVWLRENGQHFPSTV----NSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPT 60
+T+ RVW+ + + + S + +++ + G+ Y T + +P
Sbjct: 7 YTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPD 66
Query: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQ-IYTYIGSILASVNPYQPIAGLYEPATME 119
G +D+ +L+ LH ++++NL R+ ++ IYTY G +L ++NPY+ + +Y +
Sbjct: 67 ILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIIN 125
Query: 120 QYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ 179
YS +++G++ PHIFA+A E Y+ + + NQ I++SGESGAGKT S K +++ + +S
Sbjct: 126 AYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG 185
Query: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
+ E +++EK +L S+PIME+ GNAKT N+NSSRFGK++++ ++ I G
Sbjct: 186 SASEANVEEK-------VLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGAN 238
Query: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKT 299
+ YLLEK+RVV Q ERNYHIFY L A + E + L +N++Y Q G +
Sbjct: 239 MRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEG 298
Query: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTA---LG 356
+ D + A ++ S+ + R+LAGILHLGN+ F + + L
Sbjct: 299 VDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLC 358
Query: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
+L+G+D ++ L R + E + P++ QA ++RD+LA +YA F W++
Sbjct: 359 IFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDN 418
Query: 417 INSRIKGN-EDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYS 475
+N + + IG+LDI+GFE FE+N FEQF INYANEKLQ+ FN H+F LEQ EY
Sbjct: 419 VNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYM 478
Query: 476 REGLVWEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANN-HFY 534
+E + W ID+ DN C++LIE KLG+L L++EE P+ TD T +KL++ H N +
Sbjct: 479 KEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALF 538
Query: 535 VKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSR 594
KPR++ F ++H+A +V+Y G LEKN+DT ++ + +L+ S+F + +LF+
Sbjct: 539 EKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKA 598
Query: 595 NNQDTLKCG--------------------SKHRRPTVSSQFKDSLHSLMATLSSSNPFFV 634
+ + +K + TV QF++SLH LM TL+++ P +V
Sbjct: 599 ISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYV 658
Query: 635 RCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLA 694
RCIKPN K P FD+ + QLR G+LET+RI AG+ R +Q+F+ RY+VLM+
Sbjct: 659 RCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKD 718
Query: 695 LPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVL 754
+ D + C ++L+ ++Q GKTK+F R LEK R +++ A + I+ +
Sbjct: 719 VLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIR 778
Query: 755 GFLARKQYRKVLYCVV-------------------------IIQKNYRAFLLRRRFLHLK 789
G+L RK+Y ++ + IIQK +R +++RRR+ +
Sbjct: 779 GWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRR 838
Query: 790 KAAIVFQKQLRGQIARRVYRQLLAE-------------------KREQEE--------KK 822
A IV Q LRG +AR YR++L E KR ++
Sbjct: 839 AATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRR 898
Query: 823 KQEEEEKKKREEEERERER--------ERREAELRAQQEEETR-------KQQELEALQK 867
+ E KK + E R ER E + +L+ + +E+ + K LE +
Sbjct: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
Query: 868 SQKE---AELTR-ELEKQKENKQVEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQE 921
S+ E ++L R +L +++ +L L++EI L++ EQ E E + ++
Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQ 1018
Query: 922 RRDQELRRLEEEACRAAQEFLESLN---FDEIDECVRNIERSL 961
+Q + L+EE QE E+LN + E +E+ L
Sbjct: 1019 ETEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKL 1060
Score = 59.7 bits (143), Expect = 3e-08
Identities = 85/353 (24%), Positives = 139/353 (39%), Gaps = 97/353 (27%)
Query: 656 QLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVL-MRNLALPED--VRGKCTSLLQLYDA 712
Q+ Y L ++R A +++ + + R K L MR A+ VRG Y A
Sbjct: 754 QVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRG--------YQA 805
Query: 713 SNSEWQLGKTKV--FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVL--YC 768
L +TK +++ + +RR + A +V+++++ GFLAR +YRK+L +
Sbjct: 806 RCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHK 865
Query: 769 VVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKK----- 823
VIIQK R +L R + A I Q R +A+R ++L E R E KK
Sbjct: 866 AVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGM 925
Query: 824 -------------------------------QEEEEKKKREEEER--------------- 837
E +K R + ER
Sbjct: 926 ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985
Query: 838 ----------ERERERREAELRAQQEEETRKQQELE----------ALQKSQKEA----- 872
++ E+ +E + +E R +QE E L K +KEA
Sbjct: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045
Query: 873 -ELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRD 924
+ +E+ + E K VEE +LE ++ D +R++ Q L+ +L+ER D
Sbjct: 1046 VQQAKEMTETMEKKLVEETKQLELDLND-ERLRYQNLLN----EFSRLEERYD 1093
Score = 48.5 bits (114), Expect = 7e-05
Identities = 73/324 (22%), Positives = 128/324 (39%), Gaps = 102/324 (31%)
Query: 666 VRIRKAGYAVRRPFQDFYKR-YKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTK- 723
+R+RKA ++R + + R Y +R R K +++Q Y W++ +
Sbjct: 787 LRMRKAAITMQRYVRGYQARCYAKFLR--------RTKAATIIQKY------WRMYVVRR 832
Query: 724 ---------VFLRESLEQKLEKRREEEV--SHAAMVIRAHVLGFLARKQYRKVLYCVVII 772
+ L+ L L + R ++ H A++I+ V G+LAR Y++ ++ ++ +
Sbjct: 833 RYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYL 892
Query: 773 QKNYRAFLLRRRFLHLKKAAIVFQKQLR---------GQIARRVYRQ-----LLAEK--- 815
Q +R + +R LK A ++ + Q+ R+V Q L EK
Sbjct: 893 QCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTN 952
Query: 816 ------------REQEEKKKQEEEE---------------------------KKKREEEE 836
R E+ + EEE +KK EE
Sbjct: 953 LEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012
Query: 837 RERERERREAELRAQQEEETRKQQELEALQKS--QKEAELTRELEKQ--KENKQVE---- 888
+R ++ E + +EE T +QE EAL Q+ E+T +EK+ +E KQ+E
Sbjct: 1013 ADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLN 1072
Query: 889 -----------EILRLEKEIEDLQ 901
E RLE+ +DL+
Sbjct: 1073 DERLRYQNLLNEFSRLEERYDDLK 1096
Score = 37.7 bits (86), Expect = 0.12
Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 818 QEEKKKQEEEEKKKREEEERERERERREAELR-AQQEEETRKQQELEALQKSQKEAELTR 876
++EK+ ++E +K E+ R + +E ++R A+ E E+ K+QELE+ K K
Sbjct: 1166 EQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNE--LN 1223
Query: 877 ELEKQKENKQVEEI 890
EL K K E+
Sbjct: 1224 ELRKALSEKSAPEV 1237
Score = 36.2 bits (82), Expect = 0.34
Identities = 42/190 (22%), Positives = 83/190 (43%), Gaps = 25/190 (13%)
Query: 781 LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840
L++R L++ V Q +L + + + + E+R Q + E E K++E E ++
Sbjct: 1158 LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKK 1217
Query: 841 RERREAELRAQQEEETRKQQE----------LEALQKSQKEAELTRE--------LEKQK 882
+ ELR E++ + +E L +E ++ +E L QK
Sbjct: 1218 LKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
Query: 883 ENKQVEEILRLEKE----IEDLQRMKEQQELSLTEASLQ---KLQERRDQELRRLEEEAC 935
E Q ++ + +ED+Q+MK++ E++ L+ +L E + Q +R E
Sbjct: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEA 1337
Query: 936 RAAQEFLESL 945
A + ++SL
Sbjct: 1338 EALRGEIQSL 1347
Score = 35.0 bits (79), Expect = 0.76
Identities = 21/84 (25%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 827 EEKKKREEEERERERERREAELRAQQEEETRKQ----QELEALQKSQKEAELTRELEKQK 882
E + + ++ E E E E+++ +EE R+Q Q L+ +++ EA L E+ +
Sbjct: 1323 ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITR-L 1381
Query: 883 ENKQVEEILRLEKEIEDLQRMKEQ 906
N+ ++ + +LEK+ + ++++K+Q
Sbjct: 1382 TNENLDLMEQLEKQDKTVRKLKKQ 1405
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 531 bits (1369), Expect = e-150
Identities = 339/1063 (31%), Positives = 554/1063 (52%), Gaps = 115/1063 (10%)
Query: 5 FTEGTRVWLRENGQHFPSTV----NSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPT 60
+T+ RVW+ + + + S + +++ + G+ Y T + +P
Sbjct: 7 YTKFARVWIPDPEEVWKSAELLKDYKPGDKVLLLHLEEGKDLEYHLDPKTKELPHLRNPD 66
Query: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQ-IYTYIGSILASVNPYQPIAGLYEPATME 119
G +D+ +L+ LH ++++NL R+ ++ IYTY G +L ++NPY+ + +Y +
Sbjct: 67 ILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLP-IYGEDIIN 125
Query: 120 QYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ 179
YS +++G++ PHIFA+A E Y+ + + NQ I++SGESGAGKT S K +++ + +S
Sbjct: 126 AYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSG 185
Query: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
+ E +++EK +L S+PIME+ GNAKT N+NSSRFGK++++ ++ I G
Sbjct: 186 SASEANVEEK-------VLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGAN 238
Query: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKT 299
+ YLLEK+RVV Q ERNYHIFY L A + E + L +N++Y Q G +
Sbjct: 239 MRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEG 298
Query: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAGGAQVSFKTA---LG 356
+ D + A ++ S+ + R+LAGILHLGN+ F + + L
Sbjct: 299 VDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLC 358
Query: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
+L+G+D ++ L R + E + P++ QA ++RD+LA +YA F W++
Sbjct: 359 IFCDLMGVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDN 418
Query: 417 INSRIKGN-EDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYS 475
+N + + IG+LDI+GFE FE+N FEQF INYANEKLQ+ FN H+F LEQ EY
Sbjct: 419 VNQALHSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYM 478
Query: 476 REGLVWEDIDWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANN-HFY 534
+E + W ID+ DN C++LIE KLG+L L++EE P+ TD T +KL++ H N +
Sbjct: 479 KEQIPWTLIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALF 538
Query: 535 VKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSR 594
KPR++ F ++H+A +V+Y G LEKN+DT ++ + +L+ S+F + +LF+
Sbjct: 539 EKPRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKA 598
Query: 595 NNQDTLKCG--------------------SKHRRPTVSSQFKDSLHSLMATLSSSNPFFV 634
+ + +K + TV QF++SLH LM TL+++ P +V
Sbjct: 599 ISPTSATSSGRTPLTRTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYV 658
Query: 635 RCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLA 694
RCIKPN K P FD+ + QLR G+LET+RI AG+ R +Q+F+ RY+VLM+
Sbjct: 659 RCIKPNDFKFPFTFDEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVLMKQKD 718
Query: 695 LPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVL 754
+ D + C ++L+ ++Q GKTK+F R LEK R +++ A + I+ +
Sbjct: 719 VLSDRKQTCKNVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIR 778
Query: 755 GFLARKQYRKVLYCVV-------------------------IIQKNYRAFLLRRRFLHLK 789
G+L RK+Y ++ + IIQK +R +++RRR+ +
Sbjct: 779 GWLLRKKYLRMRKAAITMQRYVRGYQARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRR 838
Query: 790 KAAIVFQKQLRGQIARRVYRQLLAE-------------------KREQEE--------KK 822
A IV Q LRG +AR YR++L E KR ++
Sbjct: 839 AATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRR 898
Query: 823 KQEEEEKKKREEEERERER--------ERREAELRAQQEEETR-------KQQELEALQK 867
+ E KK + E R ER E + +L+ + +E+ + K LE +
Sbjct: 899 MMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYN 958
Query: 868 SQKE---AELTR-ELEKQKENKQVEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQE 921
S+ E ++L R +L +++ +L L++EI L++ EQ E E + ++
Sbjct: 959 SETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQ 1018
Query: 922 RRDQELRRLEEEACRAAQEFLESLN---FDEIDECVRNIERSL 961
+Q + L+EE QE E+LN + E +E+ L
Sbjct: 1019 ETEQLVSNLKEENTLLKQE-KEALNHRIVQQAKEMTETMEKKL 1060
Score = 59.7 bits (143), Expect = 3e-08
Identities = 85/353 (24%), Positives = 139/353 (39%), Gaps = 97/353 (27%)
Query: 656 QLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVL-MRNLALPED--VRGKCTSLLQLYDA 712
Q+ Y L ++R A +++ + + R K L MR A+ VRG Y A
Sbjct: 754 QVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRG--------YQA 805
Query: 713 SNSEWQLGKTKV--FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVL--YC 768
L +TK +++ + +RR + A +V+++++ GFLAR +YRK+L +
Sbjct: 806 RCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHK 865
Query: 769 VVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKK----- 823
VIIQK R +L R + A I Q R +A+R ++L E R E KK
Sbjct: 866 AVIIQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGM 925
Query: 824 -------------------------------QEEEEKKKREEEER--------------- 837
E +K R + ER
Sbjct: 926 ENKIMQLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRV 985
Query: 838 ----------ERERERREAELRAQQEEETRKQQELE----------ALQKSQKEA----- 872
++ E+ +E + +E R +QE E L K +KEA
Sbjct: 986 LSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRI 1045
Query: 873 -ELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRD 924
+ +E+ + E K VEE +LE ++ D +R++ Q L+ +L+ER D
Sbjct: 1046 VQQAKEMTETMEKKLVEETKQLELDLND-ERLRYQNLLN----EFSRLEERYD 1093
Score = 48.5 bits (114), Expect = 7e-05
Identities = 73/324 (22%), Positives = 128/324 (39%), Gaps = 102/324 (31%)
Query: 666 VRIRKAGYAVRRPFQDFYKR-YKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTK- 723
+R+RKA ++R + + R Y +R R K +++Q Y W++ +
Sbjct: 787 LRMRKAAITMQRYVRGYQARCYAKFLR--------RTKAATIIQKY------WRMYVVRR 832
Query: 724 ---------VFLRESLEQKLEKRREEEV--SHAAMVIRAHVLGFLARKQYRKVLYCVVII 772
+ L+ L L + R ++ H A++I+ V G+LAR Y++ ++ ++ +
Sbjct: 833 RYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMHAIIYL 892
Query: 773 QKNYRAFLLRRRFLHLKKAAIVFQKQLR---------GQIARRVYRQ-----LLAEK--- 815
Q +R + +R LK A ++ + Q+ R+V Q L EK
Sbjct: 893 QCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKDYKCLVEKLTN 952
Query: 816 ------------REQEEKKKQEEEE---------------------------KKKREEEE 836
R E+ + EEE +KK EE
Sbjct: 953 LEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEH 1012
Query: 837 RERERERREAELRAQQEEETRKQQELEALQKS--QKEAELTRELEKQ--KENKQVE---- 888
+R ++ E + +EE T +QE EAL Q+ E+T +EK+ +E KQ+E
Sbjct: 1013 ADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLN 1072
Query: 889 -----------EILRLEKEIEDLQ 901
E RLE+ +DL+
Sbjct: 1073 DERLRYQNLLNEFSRLEERYDDLK 1096
Score = 37.7 bits (86), Expect = 0.12
Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 818 QEEKKKQEEEEKKKREEEERERERERREAELR-AQQEEETRKQQELEALQKSQKEAELTR 876
++EK+ ++E +K E+ R + +E ++R A+ E E+ K+QELE+ K K
Sbjct: 1166 EQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNE--LN 1223
Query: 877 ELEKQKENKQVEEI 890
EL K K E+
Sbjct: 1224 ELRKALSEKSAPEV 1237
Score = 35.0 bits (79), Expect = 0.76
Identities = 21/84 (25%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 827 EEKKKREEEERERERERREAELRAQQEEETRKQ----QELEALQKSQKEAELTRELEKQK 882
E + + ++ E E E E+++ +EE R+Q Q L+ +++ EA L E+ +
Sbjct: 1350 ESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITR-L 1408
Query: 883 ENKQVEEILRLEKEIEDLQRMKEQ 906
N+ ++ + +LEK+ + ++++K+Q
Sbjct: 1409 TNENLDLMEQLEKQDKTVRKLKKQ 1432
Score = 33.5 bits (75), Expect = 2.2
Identities = 41/194 (21%), Positives = 79/194 (40%), Gaps = 30/194 (15%)
Query: 781 LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840
L++R L++ V Q +L + + + + E+R Q + E E K++E E ++
Sbjct: 1158 LQKRVTELEQEKQVMQDELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKK 1217
Query: 841 RERREAELRAQQEEETRKQQE----------LEALQKSQKEAELTRE--------LEKQK 882
+ ELR E++ + +E L +E ++ +E L QK
Sbjct: 1218 LKNELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQK 1277
Query: 883 ENKQVEEILRLEKE----IEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEE------ 932
E Q ++ + +ED+Q+MK++ E++ L++ + L E
Sbjct: 1278 EAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRSSALDYHELNEDGELWL 1337
Query: 933 --EACRAAQEFLES 944
E + A LES
Sbjct: 1338 VYEGLKQANRLLES 1351
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 518 bits (1333), Expect = e-146
Identities = 337/1015 (33%), Positives = 541/1015 (53%), Gaps = 145/1015 (14%)
Query: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQ 120
+++ V+D SL L+ ++++N+ RY +++IYTY+ +IL +VNPY I +Y ++
Sbjct: 55 SKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKS 114
Query: 121 YSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ 180
Y + LG PPH+FAIA++ +R + +Q I++SGESGAGKTE+TK +L++L+
Sbjct: 115 YQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGT 174
Query: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240
+ ++ I+E++P++EAFGNAKTV NNNSSRFGKFV+++ +K ++ GG +
Sbjct: 175 GQD---------IDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFV 225
Query: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQ--------- 291
YLLEK+R+ Q ERNYHIFY L AG + RE+ +LS+P+N+ YLN+
Sbjct: 226 SHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANK 285
Query: 292 -----------------SGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGIL 334
+G ++D + D F + TAM + EE ++ R++AG+L
Sbjct: 286 ETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVL 345
Query: 335 HLGNIEF----ITAGGAQVSFKTA--LGRSAELLGLDPTQLTDALTQRSMFL-----RGE 383
HLGNI+F T+GG + K+A L AELLGLD L +LT R M +G
Sbjct: 346 HLGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGT 405
Query: 384 EILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFKSIGILDIFGFENFEV 443
I PL V+QA ++RD+LA +Y+ F+ V+ ++N IG+LDI GFE FE
Sbjct: 406 VIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEH 465
Query: 444 NHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKL-GL 502
N FEQF INY NEKLQ++FN+ I EQ Y +EGL ++ ++DN +C+DLIE KL G+
Sbjct: 466 NSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGI 525
Query: 503 LALINEESHFPQATDSTLLEKLHSQHANNHFYV----KPRVAVNN-------FGVKHYAG 551
L +++EE+ PQ +D +H +H +HF + K ++AV+ F ++H+AG
Sbjct: 526 LDILDEENRLPQPSDQHFTSAVHQKH-KDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAG 584
Query: 552 EVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTV 611
V Y+ +EKN D L +L+ ESR FI +LFE S+ NN+DT + K +V
Sbjct: 585 AVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFES-STNNNKDTKQKAGKLSFISV 643
Query: 612 SSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKA 671
++FK L+ L+ L S+ F+RCIKPN++ F+ A +L+QL+ SGM+ + + +
Sbjct: 644 GNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQG 703
Query: 672 GYAVRRPFQDFYKRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLE 731
GY R F + Y YK M + D R C +L + + ++++ G TKVF R
Sbjct: 704 GYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKF 763
Query: 732 QKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVII-----------------QK 774
+ ++ + + H A +++ V +L +++KV +C + + QK
Sbjct: 764 AEFDQIMKSDPDHLAELVK-RVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQK 822
Query: 775 NYRAFLLRRRFLH------------------------LKKAAIVFQKQLRG------QIA 804
R +L +RR LK KQ++ +
Sbjct: 823 TIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLM 882
Query: 805 RRVYRQLLAEKREQEE----------------KKKQEEEEKKK----REEEERERERERR 844
++ ++ +++ Q+E KKKQ+EEE ++ +EE E+ER+R
Sbjct: 883 AKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREE 942
Query: 845 EAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMK 904
+ + R ++EEE R + E+EA +K ++E RE ++++ +VE L +KE E Q+
Sbjct: 943 DEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAV 1002
Query: 905 EQQE---------LSLTEASLQKLQERRDQELRRLE--------EEACRAAQEFL 942
+QE ++ +EA L + + D LRR + E+ + EFL
Sbjct: 1003 LEQERRDRELALRIAQSEAELISDEAQADLALRRNDGTRPKMTPEQMAKEMSEFL 1057
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 513 bits (1320), Expect = e-145
Identities = 342/1013 (33%), Positives = 559/1013 (55%), Gaps = 61/1013 (6%)
Query: 11 VWLRENGQHFPSTVNSCAEG--IVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDM 68
VW+ Q F + +G +VV + G K+ T+ + M+P V+DM
Sbjct: 36 VWVPSEKQGFEAASIKEEKGDEVVVELVENG-----KKVTVGKDDIQKMNPPKFSKVEDM 90
Query: 69 ASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGE 128
A LT L+ S+++NL +RY IYTY G VNPY+ + +Y ++ Y + E
Sbjct: 91 AELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHE 149
Query: 129 LPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLELSLKE 188
+PPHI+AIA+ YR + + ++Q IL +GESGAGKTE+TK ++++L+V++
Sbjct: 150 MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209
Query: 189 KTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKN 248
T +E+ +L+++PI+EAFGNAKTV N+NSSRFGKF+++N G I G I YLLEK+
Sbjct: 210 ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
Query: 249 RVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISDQESFRE 308
R +RQ ER +HIFY ++AG + + R + L NY +L+ +G V D E F+E
Sbjct: 270 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEMFQE 328
Query: 309 VITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELLGLD 365
+ AM +M FS+EE + ++++ +L LGNI F A + TA + L+G++
Sbjct: 329 TVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGIN 388
Query: 366 PTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRI--KG 423
T T ++ + + + + +QA + ++LA A Y F W++ ++N +
Sbjct: 389 VTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTH 448
Query: 424 NEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWED 483
+ +GILDI GFE FEVN FEQ INY NEKLQ+ FN +F LEQ EY REG+ W
Sbjct: 449 RQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 508
Query: 484 IDW-IDNGECLDLIEK---KLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRV 539
ID+ +D C++LIE+ G+LAL++EE FP+ATD + +EKL ++ ++ + KP+
Sbjct: 509 IDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQ 568
Query: 540 AVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVS----- 592
+ F + HYAG+V Y+ L KN D D++ +LL S F+ DL++ V
Sbjct: 569 LKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGL 628
Query: 593 ---SRNNQDTLKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPD 646
++ + +L SK ++ TV +K+ L LM TL ++ P FVRCI PN +K
Sbjct: 629 DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 688
Query: 647 QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE---DVRGKC 703
+ D +VL QLR +G+LE +RI + G+ R FQ+F +RY++L N A+P+ D + C
Sbjct: 689 KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN-AIPKGFMDGKQAC 747
Query: 704 TSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYR 763
+++ + + +++G++K+F R + LE+ R+ +++ M +A G+LARK +
Sbjct: 748 ILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 807
Query: 764 K---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK 815
K L + +IQ+N A+L R R K + +Q A+ Q E+
Sbjct: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
Query: 816 REQEEKKKQEEEEKKKREEEERE--RERERREAELRAQQEEE----TRKQQELEAL---Q 866
+++ E + +E E+K + EE+ +E+ + E EL A+ EE K+QELE +
Sbjct: 868 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
Query: 867 KSQKEAELTRELEKQKENKQV-EEILRLEKEIEDLQ--RMKEQQELSLTEASLQKLQER- 922
+++ E E R + Q E K++ +++L LE+++E+ + R K Q E EA ++KL++
Sbjct: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
Query: 923 --RDQELRRLEEEACRAAQEFLESL--NFDEIDECVRNIERSLSVGSEFSSEL 971
D + +L +E + +E + L N E +E +N+ + + SEL
Sbjct: 988 LVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1039
Score = 47.8 bits (112), Expect = 1e-04
Identities = 49/195 (25%), Positives = 88/195 (45%), Gaps = 21/195 (10%)
Query: 805 RRVYRQLLAEKREQEEKKKQEE---EEKKKREEEERERE---------RERREAELRAQQ 852
R++ RQL + E E+++KQ KKK E + ++ E RE +LR Q
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 853 EEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQEL--- 909
+ Q+ELE + S+ E T + ++K ++++L++++ +R ++Q +L
Sbjct: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 910 SLTEASLQKLQERR--DQELRRLEEEACRAAQEFLESL-NFDEIDECVRNIERSLSVGSE 966
L E L R E RRLE + +E E N + + + VR ++ +
Sbjct: 1712 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR---KATQQAEQ 1768
Query: 967 FSSELAESACEEKPN 981
S+ELA + N
Sbjct: 1769 LSNELATERSTAQKN 1783
Score = 46.2 bits (108), Expect = 3e-04
Identities = 52/237 (21%), Positives = 101/237 (42%), Gaps = 19/237 (8%)
Query: 708 QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY 767
+L + QL + K L+E L+ + E E E + + L + + +
Sbjct: 874 ELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR--- 930
Query: 768 CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEE 827
+ ++ R L+ + + + ++QL + A R QL EK E K K+ E+
Sbjct: 931 ---LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL--EKVTAEAKIKKLED 985
Query: 828 EKKKREEEERERERER-----REAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
E +++ + +ER R ++L EE K + L L+ + E+ +K
Sbjct: 986 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1045
Query: 883 ENKQVEEILRLEKEIE-DLQRMKE-----QQELSLTEASLQKLQERRDQELRRLEEE 933
E K +E+ +L++++E D E Q +++ + L K +E L RL++E
Sbjct: 1046 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Score = 45.4 bits (106), Expect = 6e-04
Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 45/231 (19%)
Query: 810 QLLAEKREQEEKKKQEEEEKKKREEE---------ERERERERREAELRAQQEEETRKQQ 860
QL + E +KQ + EK++ EE + E+ R EA + +EE +Q
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750
Query: 861 ELEAL-----QKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQRMKEQQE----- 908
+EA+ + +Q+ +L+ EL ++ Q E R LE++ ++L+ + E
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
Query: 909 -----LSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSV 963
++ EA + +L+E+ +QE R + AA + L+ + ++ E + +E +
Sbjct: 1811 KFKSTIAALEAKIAQLEEQVEQEAREKQ-----AATKSLKQKD-KKLKEILLQVEDERKM 1864
Query: 964 GSEFSSEL-------------AESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
++ + E A EE N ++ + E+DE E+++
Sbjct: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/193 (21%), Positives = 87/193 (45%), Gaps = 10/193 (5%)
Query: 788 LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847
L+K Q++L + ++ L E++++K + ++K + ER+R EAE
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
Query: 848 LRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQ 907
R ++ + + LE ++++E E T ++ K + V + K + +L++ K
Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
Query: 908 ELSLTEASLQ------KLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
E + E Q +LQ D +LR + +A + E ++ +E R ++R
Sbjct: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
Query: 961 LSVGSEFSSELAE 973
L E+ +EL +
Sbjct: 1598 L---HEYETELED 1607
Score = 41.2 bits (95), Expect = 0.011
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 809 RQLLAEKREQEEKKKQEEEEKKKREEE-ERERERERREAELRAQQEEETRKQQELEALQK 867
R+LL E+ EEEEK K + + + E E E+R ++EE++R QELE L++
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKR 1058
Query: 868 ----------------SQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSL 911
+ AEL +L K++E Q + RL+ EI Q+ +++
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA-ALARLDDEI--AQKNNALKKIRE 1115
Query: 912 TEASLQKLQERRDQE--LRRLEEEACRAAQEFLESL 945
E + LQE D E R E+ R E LE+L
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151
Score = 40.4 bits (93), Expect = 0.018
Identities = 29/116 (25%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Query: 811 LLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQK 870
L A+ + EE+ +QE EK+ + ++++++ +E L+ + E + +Q + +A + + +
Sbjct: 1819 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1878
Query: 871 EAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
+L R+LE+ +E Q R K +L E E E + K + RR E
Sbjct: 1879 VKQLKRQLEEAEEESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNE 1933
Score = 40.0 bits (92), Expect = 0.024
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 15/154 (9%)
Query: 814 EKREQEEKKKQEEEEKKKREEEER-------ERERERREAELRAQQEEETRKQQELEALQ 866
E E+ +K+ Q+E E ++ EE+ E+ + R + EL + ++Q + L+
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 867 KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
K Q++ + EK +K +E R E E R KE + LSL A + L+ + +E
Sbjct: 1448 KKQRKFDQLLAEEKNISSKYADERDRAEAE----AREKETKALSLARALEEALEAK--EE 1501
Query: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
L R + +A E L S + D++ + V +E+S
Sbjct: 1502 LER-TNKMLKAEMEDLVS-SKDDVGKNVHELEKS 1533
Score = 39.7 bits (91), Expect = 0.031
Identities = 88/372 (23%), Positives = 149/372 (40%), Gaps = 54/372 (14%)
Query: 684 KRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVS 743
+R L NLA E+ T L +++ SE ++ K +KL+++ E + S
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 744 H-----AAMVIRAHVLGFLARKQYRKVLYCVV-----IIQKNYRAFLLRRRFLHLKKAAI 793
A + + L K+ ++ + I QKN +R H+
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD--- 1122
Query: 794 VFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKRE----------EEERERERER 843
Q+ L + A R K E++++ EE E K E ++E +RE+
Sbjct: 1123 -LQEDLDSERAAR-------NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Query: 844 REAELRAQQEEETRKQQELEALQKSQKEA----ELTRELEKQK-------ENKQV--EEI 890
L+ +EETR E + + QK A ELT +LE+ K +NKQ +E
Sbjct: 1175 EVTVLKKALDEETR-SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1233
Query: 891 LRLEKEIEDLQRMKEQQE--LSLTEASLQKLQER-RDQELRRLE-EEACRAAQEFLESLN 946
L E+ L + K++ E EA +Q+LQ + D E R E + Q +ES+
Sbjct: 1234 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 947 --FDEIDECVRNIER---SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
+E + + + SLS + + EL + +K N + EEE + + D
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 1002 DAFKDSPNPSEH 1013
+ + N H
Sbjct: 1354 EEMEAKQNLERH 1365
Score = 38.5 bits (88), Expect = 0.068
Identities = 56/219 (25%), Positives = 100/219 (45%), Gaps = 34/219 (15%)
Query: 809 RQLLAEKREQE----EKKKQEEEEKKKR-----EEEERERERERREAELRAQQEEETRKQ 859
++LL E+ Q+ K +Q EEE+ EE E ++ ER + L Q + +K
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Query: 860 QE----LEALQKS----QKEAE-LTRELEKQKE--NKQVEEILRLEKEIEDL-QRMKEQQ 907
Q+ +EAL++ QKE E LT++ E++ +K + RL++E++DL + Q+
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Query: 908 ELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEF 967
+L ++L+K Q + DQ L A ++ + S DE D +
Sbjct: 1441 QL---VSNLEKKQRKFDQLL---------AEEKNISSKYADERDRAEAEAREKETKALSL 1488
Query: 968 SSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKD 1006
+ L E A E K + + E+++ + DD K+
Sbjct: 1489 ARAL-EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
Score = 37.7 bits (86), Expect = 0.12
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 16/119 (13%)
Query: 818 QEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELE--------ALQKSQ 869
Q+ ++ +EE ++K + R+ E L+ Q +EE +Q LE L S+
Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1377
Query: 870 KE-AELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927
K+ + +E +E K+ R +KEIE+L + E++ + + L+K + R QEL
Sbjct: 1378 KKLQDFASTVEALEEGKK-----RFQKEIENLTQQYEEKAAAYDK--LEKTKNRLQQEL 1429
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 513 bits (1320), Expect = e-145
Identities = 342/1013 (33%), Positives = 559/1013 (55%), Gaps = 61/1013 (6%)
Query: 11 VWLRENGQHFPSTVNSCAEG--IVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDM 68
VW+ Q F + +G +VV + G K+ T+ + M+P V+DM
Sbjct: 36 VWVPSEKQGFEAASIKEEKGDEVVVELVENG-----KKVTVGKDDIQKMNPPKFSKVEDM 90
Query: 69 ASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGE 128
A LT L+ S+++NL +RY IYTY G VNPY+ + +Y ++ Y + E
Sbjct: 91 AELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHE 149
Query: 129 LPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLELSLKE 188
+PPHI+AIA+ YR + + ++Q IL +GESGAGKTE+TK ++++L+V++
Sbjct: 150 MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209
Query: 189 KTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKN 248
T +E+ +L+++PI+EAFGNAKTV N+NSSRFGKF+++N G I G I YLLEK+
Sbjct: 210 ITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKS 269
Query: 249 RVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTISDQESFRE 308
R +RQ ER +HIFY ++AG + + R + L NY +L+ +G V D E F+E
Sbjct: 270 RAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQDDEMFQE 328
Query: 309 VITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELLGLD 365
+ AM +M FS+EE + ++++ +L LGNI F A + TA + L+G++
Sbjct: 329 TVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGIN 388
Query: 366 PTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRI--KG 423
T T ++ + + + + +QA + ++LA A Y F W++ ++N +
Sbjct: 389 VTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTH 448
Query: 424 NEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWED 483
+ +GILDI GFE FEVN FEQ INY NEKLQ+ FN +F LEQ EY REG+ W
Sbjct: 449 RQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNF 508
Query: 484 IDW-IDNGECLDLIEK---KLGLLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRV 539
ID+ +D C++LIE+ G+LAL++EE FP+ATD + +EKL ++ ++ + KP+
Sbjct: 509 IDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQ 568
Query: 540 AVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVS----- 592
+ F + HYAG+V Y+ L KN D D++ +LL S F+ DL++ V
Sbjct: 569 LKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGL 628
Query: 593 ---SRNNQDTLKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPD 646
++ + +L SK ++ TV +K+ L LM TL ++ P FVRCI PN +K
Sbjct: 629 DQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSG 688
Query: 647 QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE---DVRGKC 703
+ D +VL QLR +G+LE +RI + G+ R FQ+F +RY++L N A+P+ D + C
Sbjct: 689 KLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN-AIPKGFMDGKQAC 747
Query: 704 TSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYR 763
+++ + + +++G++K+F R + LE+ R+ +++ M +A G+LARK +
Sbjct: 748 ILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFA 807
Query: 764 K---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK 815
K L + +IQ+N A+L R R K + +Q A+ Q E+
Sbjct: 808 KRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKER 867
Query: 816 REQEEKKKQEEEEKKKREEEERE--RERERREAELRAQQEEE----TRKQQELEAL---Q 866
+++ E + +E E+K + EE+ +E+ + E EL A+ EE K+QELE +
Sbjct: 868 QQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEM 927
Query: 867 KSQKEAELTRELEKQKENKQV-EEILRLEKEIEDLQ--RMKEQQELSLTEASLQKLQER- 922
+++ E E R + Q E K++ +++L LE+++E+ + R K Q E EA ++KL++
Sbjct: 928 EARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEI 987
Query: 923 --RDQELRRLEEEACRAAQEFLESL--NFDEIDECVRNIERSLSVGSEFSSEL 971
D + +L +E + +E + L N E +E +N+ + + SEL
Sbjct: 988 LVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1039
Score = 47.8 bits (112), Expect = 1e-04
Identities = 49/195 (25%), Positives = 88/195 (45%), Gaps = 21/195 (10%)
Query: 805 RRVYRQLLAEKREQEEKKKQEE---EEKKKREEEERERE---------RERREAELRAQQ 852
R++ RQL + E E+++KQ KKK E + ++ E RE +LR Q
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 853 EEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQEL--- 909
+ Q+ELE + S+ E T + ++K ++++L++++ +R ++Q +L
Sbjct: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 910 SLTEASLQKLQERR--DQELRRLEEEACRAAQEFLESL-NFDEIDECVRNIERSLSVGSE 966
L E L R E RRLE + +E E N + + + VR ++ +
Sbjct: 1712 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR---KATQQAEQ 1768
Query: 967 FSSELAESACEEKPN 981
S+ELA + N
Sbjct: 1769 LSNELATERSTAQKN 1783
Score = 46.2 bits (108), Expect = 3e-04
Identities = 52/237 (21%), Positives = 101/237 (42%), Gaps = 19/237 (8%)
Query: 708 QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY 767
+L + QL + K L+E L+ + E E E + + L + + +
Sbjct: 874 ELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR--- 930
Query: 768 CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEE 827
+ ++ R L+ + + + ++QL + A R QL EK E K K+ E+
Sbjct: 931 ---LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL--EKVTAEAKIKKLED 985
Query: 828 EKKKREEEERERERER-----REAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
E +++ + +ER R ++L EE K + L L+ + E+ +K
Sbjct: 986 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1045
Query: 883 ENKQVEEILRLEKEIE-DLQRMKE-----QQELSLTEASLQKLQERRDQELRRLEEE 933
E K +E+ +L++++E D E Q +++ + L K +E L RL++E
Sbjct: 1046 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1102
Score = 45.4 bits (106), Expect = 6e-04
Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 45/231 (19%)
Query: 810 QLLAEKREQEEKKKQEEEEKKKREEE---------ERERERERREAELRAQQEEETRKQQ 860
QL + E +KQ + EK++ EE + E+ R EA + +EE +Q
Sbjct: 1691 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1750
Query: 861 ELEAL-----QKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQRMKEQQE----- 908
+EA+ + +Q+ +L+ EL ++ Q E R LE++ ++L+ + E
Sbjct: 1751 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1810
Query: 909 -----LSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSV 963
++ EA + +L+E+ +QE R + AA + L+ + ++ E + +E +
Sbjct: 1811 KFKSTIAALEAKIAQLEEQVEQEAREKQ-----AATKSLKQKD-KKLKEILLQVEDERKM 1864
Query: 964 GSEFSSEL-------------AESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
++ + E A EE N ++ + E+DE E+++
Sbjct: 1865 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1915
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/193 (21%), Positives = 87/193 (45%), Gaps = 10/193 (5%)
Query: 788 LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847
L+K Q++L + ++ L E++++K + ++K + ER+R EAE
Sbjct: 1418 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1477
Query: 848 LRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQ 907
R ++ + + LE ++++E E T ++ K + V + K + +L++ K
Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
Query: 908 ELSLTEASLQ------KLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
E + E Q +LQ D +LR + +A + E ++ +E R ++R
Sbjct: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
Query: 961 LSVGSEFSSELAE 973
L E+ +EL +
Sbjct: 1598 L---HEYETELED 1607
Score = 41.2 bits (95), Expect = 0.011
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 809 RQLLAEKREQEEKKKQEEEEKKKREEE-ERERERERREAELRAQQEEETRKQQELEALQK 867
R+LL E+ EEEEK K + + + E E E+R ++EE++R QELE L++
Sbjct: 1001 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKR 1058
Query: 868 ----------------SQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSL 911
+ AEL +L K++E Q + RL+ EI Q+ +++
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA-ALARLDDEI--AQKNNALKKIRE 1115
Query: 912 TEASLQKLQERRDQE--LRRLEEEACRAAQEFLESL 945
E + LQE D E R E+ R E LE+L
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1151
Score = 40.0 bits (92), Expect = 0.024
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 15/154 (9%)
Query: 814 EKREQEEKKKQEEEEKKKREEEER-------ERERERREAELRAQQEEETRKQQELEALQ 866
E E+ +K+ Q+E E ++ EE+ E+ + R + EL + ++Q + L+
Sbjct: 1388 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1447
Query: 867 KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
K Q++ + EK +K +E R E E R KE + LSL A + L+ + +E
Sbjct: 1448 KKQRKFDQLLAEEKNISSKYADERDRAEAE----AREKETKALSLARALEEALEAK--EE 1501
Query: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
L R + +A E L S + D++ + V +E+S
Sbjct: 1502 LER-TNKMLKAEMEDLVS-SKDDVGKNVHELEKS 1533
Score = 39.7 bits (91), Expect = 0.031
Identities = 88/372 (23%), Positives = 149/372 (40%), Gaps = 54/372 (14%)
Query: 684 KRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVS 743
+R L NLA E+ T L +++ SE ++ K +KL+++ E + S
Sbjct: 1006 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1065
Query: 744 H-----AAMVIRAHVLGFLARKQYRKVLYCVV-----IIQKNYRAFLLRRRFLHLKKAAI 793
A + + L K+ ++ + I QKN +R H+
Sbjct: 1066 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD--- 1122
Query: 794 VFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKRE----------EEERERERER 843
Q+ L + A R K E++++ EE E K E ++E +RE+
Sbjct: 1123 -LQEDLDSERAAR-------NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Query: 844 REAELRAQQEEETRKQQELEALQKSQKEA----ELTRELEKQK-------ENKQV--EEI 890
L+ +EETR E + + QK A ELT +LE+ K +NKQ +E
Sbjct: 1175 EVTVLKKALDEETR-SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1233
Query: 891 LRLEKEIEDLQRMKEQQE--LSLTEASLQKLQER-RDQELRRLE-EEACRAAQEFLESLN 946
L E+ L + K++ E EA +Q+LQ + D E R E + Q +ES+
Sbjct: 1234 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1293
Query: 947 --FDEIDECVRNIER---SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
+E + + + SLS + + EL + +K N + EEE + + D
Sbjct: 1294 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1353
Query: 1002 DAFKDSPNPSEH 1013
+ + N H
Sbjct: 1354 EEMEAKQNLERH 1365
Score = 38.5 bits (88), Expect = 0.068
Identities = 56/219 (25%), Positives = 100/219 (45%), Gaps = 34/219 (15%)
Query: 809 RQLLAEKREQE----EKKKQEEEEKKKR-----EEEERERERERREAELRAQQEEETRKQ 859
++LL E+ Q+ K +Q EEE+ EE E ++ ER + L Q + +K
Sbjct: 1321 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1380
Query: 860 QE----LEALQKS----QKEAE-LTRELEKQKE--NKQVEEILRLEKEIEDL-QRMKEQQ 907
Q+ +EAL++ QKE E LT++ E++ +K + RL++E++DL + Q+
Sbjct: 1381 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1440
Query: 908 ELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEF 967
+L ++L+K Q + DQ L A ++ + S DE D +
Sbjct: 1441 QL---VSNLEKKQRKFDQLL---------AEEKNISSKYADERDRAEAEAREKETKALSL 1488
Query: 968 SSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKD 1006
+ L E A E K + + E+++ + DD K+
Sbjct: 1489 ARAL-EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
Score = 37.7 bits (86), Expect = 0.12
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 16/119 (13%)
Query: 818 QEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELE--------ALQKSQ 869
Q+ ++ +EE ++K + R+ E L+ Q +EE +Q LE L S+
Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1377
Query: 870 KE-AELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927
K+ + +E +E K+ R +KEIE+L + E++ + + L+K + R QEL
Sbjct: 1378 KKLQDFASTVEALEEGKK-----RFQKEIENLTQQYEEKAAAYDK--LEKTKNRLQQEL 1429
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 509 bits (1310), Expect = e-143
Identities = 343/1020 (33%), Positives = 563/1020 (55%), Gaps = 68/1020 (6%)
Query: 11 VWLRENGQHFPSTVNSCAEG--IVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDM 68
VW+ Q F + +G +VV + G K+ T+ + M+P V+DM
Sbjct: 36 VWVPSEKQGFEAASIKEEKGDEVVVELVENG-----KKVTVGKDDIQKMNPPKFSKVEDM 90
Query: 69 ASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGE 128
A LT L+ S+++NL +RY IYTY G VNPY+ + +Y ++ Y + E
Sbjct: 91 AELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHE 149
Query: 129 LPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ---SLELS 185
+PPHI+AIA+ YR + + ++Q IL +GESGAGKTE+TK ++++L+V++ + S
Sbjct: 150 MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209
Query: 186 LKEKTSC----VERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
+ + S +E+ +L+++PI+EAFGNAKTV N+NSSRFGKF+++N G I G I
Sbjct: 210 ITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 269
Query: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTIS 301
YLLEK+R +RQ ER +HIFY ++AG + + R + L NY +L+ +G V
Sbjct: 270 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQ 328
Query: 302 DQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRS 358
D E F+E + AM +M FS+EE + ++++ +L LGNI F A + TA +
Sbjct: 329 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 388
Query: 359 AELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKIN 418
L+G++ T T ++ + + + + +QA + ++LA A Y F W++ ++N
Sbjct: 389 CHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN 448
Query: 419 SRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSR 476
+ + +GILDI GFE FEVN FEQ INY NEKLQ+ FN +F LEQ EY R
Sbjct: 449 KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQR 508
Query: 477 EGLVWEDIDW-IDNGECLDLIEK---KLGLLALINEESHFPQATDSTLLEKLHSQHANNH 532
EG+ W ID+ +D C++LIE+ G+LAL++EE FP+ATD + +EKL ++ ++
Sbjct: 509 EGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHP 568
Query: 533 FYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEH 590
+ KP+ + F + HYAG+V Y+ L KN D D++ +LL S F+ DL++
Sbjct: 569 KFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD 628
Query: 591 VS--------SRNNQDTLKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKP 639
V ++ + +L SK ++ TV +K+ L LM TL ++ P FVRCI P
Sbjct: 629 VDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIP 688
Query: 640 NMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE-- 697
N +K + D +VL QLR +G+LE +RI + G+ R FQ+F +RY++L N A+P+
Sbjct: 689 NHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN-AIPKGF 747
Query: 698 -DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGF 756
D + C +++ + + +++G++K+F R + LE+ R+ +++ M +A G+
Sbjct: 748 MDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGY 807
Query: 757 LARKQYRK---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQKQLRGQIARRVY 808
LARK + K L + +IQ+N A+L R R K + +Q A+
Sbjct: 808 LARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDE 867
Query: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERE--RERERREAELRAQQEEE----TRKQQEL 862
Q E++++ E + +E E+K + EE+ +E+ + E EL A+ EE K+QEL
Sbjct: 868 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 927
Query: 863 EAL---QKSQKEAELTRELEKQKENKQV-EEILRLEKEIEDLQ--RMKEQQELSLTEASL 916
E + +++ E E R + Q E K++ +++L LE+++E+ + R K Q E EA +
Sbjct: 928 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 987
Query: 917 QKLQER---RDQELRRLEEEACRAAQEFLESL--NFDEIDECVRNIERSLSVGSEFSSEL 971
+KL++ D + +L +E + +E + L N E +E +N+ + + SEL
Sbjct: 988 KKLEDEILVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046
Score = 47.8 bits (112), Expect = 1e-04
Identities = 49/195 (25%), Positives = 88/195 (45%), Gaps = 21/195 (10%)
Query: 805 RRVYRQLLAEKREQEEKKKQEE---EEKKKREEEERERE---------RERREAELRAQQ 852
R++ RQL + E E+++KQ KKK E + ++ E RE +LR Q
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 853 EEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQEL--- 909
+ Q+ELE + S+ E T + ++K ++++L++++ +R ++Q +L
Sbjct: 1659 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 910 SLTEASLQKLQERR--DQELRRLEEEACRAAQEFLESL-NFDEIDECVRNIERSLSVGSE 966
L E L R E RRLE + +E E N + + + VR ++ +
Sbjct: 1719 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR---KATQQAEQ 1775
Query: 967 FSSELAESACEEKPN 981
S+ELA + N
Sbjct: 1776 LSNELATERSTAQKN 1790
Score = 46.2 bits (108), Expect = 3e-04
Identities = 52/237 (21%), Positives = 101/237 (42%), Gaps = 19/237 (8%)
Query: 708 QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY 767
+L + QL + K L+E L+ + E E E + + L + + +
Sbjct: 881 ELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR--- 937
Query: 768 CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEE 827
+ ++ R L+ + + + ++QL + A R QL EK E K K+ E+
Sbjct: 938 ---LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL--EKVTAEAKIKKLED 992
Query: 828 EKKKREEEERERERER-----REAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
E +++ + +ER R ++L EE K + L L+ + E+ +K
Sbjct: 993 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1052
Query: 883 ENKQVEEILRLEKEIE-DLQRMKE-----QQELSLTEASLQKLQERRDQELRRLEEE 933
E K +E+ +L++++E D E Q +++ + L K +E L RL++E
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Score = 45.4 bits (106), Expect = 6e-04
Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 45/231 (19%)
Query: 810 QLLAEKREQEEKKKQEEEEKKKREEE---------ERERERERREAELRAQQEEETRKQQ 860
QL + E +KQ + EK++ EE + E+ R EA + +EE +Q
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1757
Query: 861 ELEAL-----QKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQRMKEQQE----- 908
+EA+ + +Q+ +L+ EL ++ Q E R LE++ ++L+ + E
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1817
Query: 909 -----LSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSV 963
++ EA + +L+E+ +QE R + AA + L+ + ++ E + +E +
Sbjct: 1818 KFKSTIAALEAKIAQLEEQVEQEAREKQ-----AATKSLKQKD-KKLKEILLQVEDERKM 1871
Query: 964 GSEFSSEL-------------AESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
++ + E A EE N ++ + E+DE E+++
Sbjct: 1872 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1922
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/193 (21%), Positives = 87/193 (45%), Gaps = 10/193 (5%)
Query: 788 LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847
L+K Q++L + ++ L E++++K + ++K + ER+R EAE
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484
Query: 848 LRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQ 907
R ++ + + LE ++++E E T ++ K + V + K + +L++ K
Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1544
Query: 908 ELSLTEASLQ------KLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
E + E Q +LQ D +LR + +A + E ++ +E R ++R
Sbjct: 1545 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1604
Query: 961 LSVGSEFSSELAE 973
L E+ +EL +
Sbjct: 1605 L---HEYETELED 1614
Score = 41.2 bits (95), Expect = 0.011
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 809 RQLLAEKREQEEKKKQEEEEKKKREEE-ERERERERREAELRAQQEEETRKQQELEALQK 867
R+LL E+ EEEEK K + + + E E E+R ++EE++R QELE L++
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKR 1065
Query: 868 ----------------SQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSL 911
+ AEL +L K++E Q + RL+ EI Q+ +++
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA-ALARLDDEI--AQKNNALKKIRE 1122
Query: 912 TEASLQKLQERRDQE--LRRLEEEACRAAQEFLESL 945
E + LQE D E R E+ R E LE+L
Sbjct: 1123 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1158
Score = 40.4 bits (93), Expect = 0.018
Identities = 29/116 (25%), Positives = 58/116 (50%), Gaps = 1/116 (0%)
Query: 811 LLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQK 870
L A+ + EE+ +QE EK+ + ++++++ +E L+ + E + +Q + +A + + +
Sbjct: 1826 LEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNAR 1885
Query: 871 EAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
+L R+LE+ +E Q R K +L E E E + K + RR E
Sbjct: 1886 VKQLKRQLEEAEEESQRINANR-RKLQRELDEATESNEAMGREVNALKSKLRRGNE 1940
Score = 40.0 bits (92), Expect = 0.024
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 15/154 (9%)
Query: 814 EKREQEEKKKQEEEEKKKREEEER-------ERERERREAELRAQQEEETRKQQELEALQ 866
E E+ +K+ Q+E E ++ EE+ E+ + R + EL + ++Q + L+
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 867 KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
K Q++ + EK +K +E R E E R KE + LSL A + L+ + +E
Sbjct: 1455 KKQRKFDQLLAEEKNISSKYADERDRAEAE----AREKETKALSLARALEEALEAK--EE 1508
Query: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
L R + +A E L S + D++ + V +E+S
Sbjct: 1509 LER-TNKMLKAEMEDLVS-SKDDVGKNVHELEKS 1540
Score = 39.7 bits (91), Expect = 0.031
Identities = 88/372 (23%), Positives = 149/372 (40%), Gaps = 54/372 (14%)
Query: 684 KRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVS 743
+R L NLA E+ T L +++ SE ++ K +KL+++ E + S
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 744 H-----AAMVIRAHVLGFLARKQYRKVLYCVV-----IIQKNYRAFLLRRRFLHLKKAAI 793
A + + L K+ ++ + I QKN +R H+
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD--- 1129
Query: 794 VFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKRE----------EEERERERER 843
Q+ L + A R K E++++ EE E K E ++E +RE+
Sbjct: 1130 -LQEDLDSERAAR-------NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
Query: 844 REAELRAQQEEETRKQQELEALQKSQKEA----ELTRELEKQK-------ENKQV--EEI 890
L+ +EETR E + + QK A ELT +LE+ K +NKQ +E
Sbjct: 1182 EVTVLKKALDEETR-SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1240
Query: 891 LRLEKEIEDLQRMKEQQE--LSLTEASLQKLQER-RDQELRRLE-EEACRAAQEFLESLN 946
L E+ L + K++ E EA +Q+LQ + D E R E + Q +ES+
Sbjct: 1241 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 947 --FDEIDECVRNIER---SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
+E + + + SLS + + EL + +K N + EEE + + D
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 1002 DAFKDSPNPSEH 1013
+ + N H
Sbjct: 1361 EEMEAKQNLERH 1372
Score = 38.5 bits (88), Expect = 0.068
Identities = 56/219 (25%), Positives = 100/219 (45%), Gaps = 34/219 (15%)
Query: 809 RQLLAEKREQE----EKKKQEEEEKKKR-----EEEERERERERREAELRAQQEEETRKQ 859
++LL E+ Q+ K +Q EEE+ EE E ++ ER + L Q + +K
Sbjct: 1328 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1387
Query: 860 QE----LEALQKS----QKEAE-LTRELEKQKE--NKQVEEILRLEKEIEDL-QRMKEQQ 907
Q+ +EAL++ QKE E LT++ E++ +K + RL++E++DL + Q+
Sbjct: 1388 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1447
Query: 908 ELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEF 967
+L ++L+K Q + DQ L A ++ + S DE D +
Sbjct: 1448 QL---VSNLEKKQRKFDQLL---------AEEKNISSKYADERDRAEAEAREKETKALSL 1495
Query: 968 SSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKD 1006
+ L E A E K + + E+++ + DD K+
Sbjct: 1496 ARAL-EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1533
Score = 37.7 bits (86), Expect = 0.12
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 16/119 (13%)
Query: 818 QEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELE--------ALQKSQ 869
Q+ ++ +EE ++K + R+ E L+ Q +EE +Q LE L S+
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1384
Query: 870 KE-AELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927
K+ + +E +E K+ R +KEIE+L + E++ + + L+K + R QEL
Sbjct: 1385 KKLQDFASTVEALEEGKK-----RFQKEIENLTQQYEEKAAAYDK--LEKTKNRLQQEL 1436
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 509 bits (1310), Expect = e-143
Identities = 343/1020 (33%), Positives = 563/1020 (55%), Gaps = 68/1020 (6%)
Query: 11 VWLRENGQHFPSTVNSCAEG--IVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDM 68
VW+ Q F + +G +VV + G K+ T+ + M+P V+DM
Sbjct: 36 VWVPSEKQGFEAASIKEEKGDEVVVELVENG-----KKVTVGKDDIQKMNPPKFSKVEDM 90
Query: 69 ASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGE 128
A LT L+ S+++NL +RY IYTY G VNPY+ + +Y ++ Y + E
Sbjct: 91 AELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLP-IYSEKIVDMYKGKKRHE 149
Query: 129 LPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ---SLELS 185
+PPHI+AIA+ YR + + ++Q IL +GESGAGKTE+TK ++++L+V++ + S
Sbjct: 150 MPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKDTS 209
Query: 186 LKEKTSC----VERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
+ + S +E+ +L+++PI+EAFGNAKTV N+NSSRFGKF+++N G I G I
Sbjct: 210 ITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIE 269
Query: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVEDKTIS 301
YLLEK+R +RQ ER +HIFY ++AG + + R + L NY +L+ +G V
Sbjct: 270 TYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLS-NGFVPIPAAQ 328
Query: 302 DQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRS 358
D E F+E + AM +M FS+EE + ++++ +L LGNI F A + TA +
Sbjct: 329 DDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKV 388
Query: 359 AELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKIN 418
L+G++ T T ++ + + + + +QA + ++LA A Y F W++ ++N
Sbjct: 389 CHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVN 448
Query: 419 SRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSR 476
+ + +GILDI GFE FEVN FEQ INY NEKLQ+ FN +F LEQ EY R
Sbjct: 449 KALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQR 508
Query: 477 EGLVWEDIDW-IDNGECLDLIEK---KLGLLALINEESHFPQATDSTLLEKLHSQHANNH 532
EG+ W ID+ +D C++LIE+ G+LAL++EE FP+ATD + +EKL ++ ++
Sbjct: 509 EGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHP 568
Query: 533 FYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEH 590
+ KP+ + F + HYAG+V Y+ L KN D D++ +LL S F+ DL++
Sbjct: 569 KFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKD 628
Query: 591 VS--------SRNNQDTLKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKP 639
V ++ + +L SK ++ TV +K+ L LM TL ++ P FVRCI P
Sbjct: 629 VDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIP 688
Query: 640 NMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE-- 697
N +K + D +VL QLR +G+LE +RI + G+ R FQ+F +RY++L N A+P+
Sbjct: 689 NHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN-AIPKGF 747
Query: 698 -DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGF 756
D + C +++ + + +++G++K+F R + LE+ R+ +++ M +A G+
Sbjct: 748 MDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGY 807
Query: 757 LARKQYRK---VLYCVVIIQKNYRAFLLRR-----RFLHLKKAAIVFQKQLRGQIARRVY 808
LARK + K L + +IQ+N A+L R R K + +Q A+
Sbjct: 808 LARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDE 867
Query: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERE--RERERREAELRAQQEEE----TRKQQEL 862
Q E++++ E + +E E+K + EE+ +E+ + E EL A+ EE K+QEL
Sbjct: 868 LQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQEL 927
Query: 863 EAL---QKSQKEAELTRELEKQKENKQV-EEILRLEKEIEDLQ--RMKEQQELSLTEASL 916
E + +++ E E R + Q E K++ +++L LE+++E+ + R K Q E EA +
Sbjct: 928 EEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKI 987
Query: 917 QKLQER---RDQELRRLEEEACRAAQEFLESL--NFDEIDECVRNIERSLSVGSEFSSEL 971
+KL++ D + +L +E + +E + L N E +E +N+ + + SEL
Sbjct: 988 KKLEDEILVMDDQNNKLSKER-KLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISEL 1046
Score = 47.8 bits (112), Expect = 1e-04
Identities = 49/195 (25%), Positives = 88/195 (45%), Gaps = 21/195 (10%)
Query: 805 RRVYRQLLAEKREQEEKKKQEE---EEKKKREEEERERE---------RERREAELRAQQ 852
R++ RQL + E E+++KQ KKK E + ++ E RE +LR Q
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 853 EEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQEL--- 909
+ Q+ELE + S+ E T + ++K ++++L++++ +R ++Q +L
Sbjct: 1659 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 910 SLTEASLQKLQERR--DQELRRLEEEACRAAQEFLESL-NFDEIDECVRNIERSLSVGSE 966
L E L R E RRLE + +E E N + + + VR ++ +
Sbjct: 1719 ELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVR---KATQQAEQ 1775
Query: 967 FSSELAESACEEKPN 981
S+ELA + N
Sbjct: 1776 LSNELATERSTAQKN 1790
Score = 46.2 bits (108), Expect = 3e-04
Identities = 52/237 (21%), Positives = 101/237 (42%), Gaps = 19/237 (8%)
Query: 708 QLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY 767
+L + QL + K L+E L+ + E E E + + L + + +
Sbjct: 881 ELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEAR--- 937
Query: 768 CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEE 827
+ ++ R L+ + + + ++QL + A R QL EK E K K+ E+
Sbjct: 938 ---LEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQL--EKVTAEAKIKKLED 992
Query: 828 EKKKREEEERERERER-----REAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
E +++ + +ER R ++L EE K + L L+ + E+ +K
Sbjct: 993 EILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKK 1052
Query: 883 ENKQVEEILRLEKEIE-DLQRMKE-----QQELSLTEASLQKLQERRDQELRRLEEE 933
E K +E+ +L++++E D E Q +++ + L K +E L RL++E
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDE 1109
Score = 45.4 bits (106), Expect = 6e-04
Identities = 50/231 (21%), Positives = 101/231 (43%), Gaps = 45/231 (19%)
Query: 810 QLLAEKREQEEKKKQEEEEKKKREEE---------ERERERERREAELRAQQEEETRKQQ 860
QL + E +KQ + EK++ EE + E+ R EA + +EE +Q
Sbjct: 1698 QLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQG 1757
Query: 861 ELEAL-----QKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQRMKEQQE----- 908
+EA+ + +Q+ +L+ EL ++ Q E R LE++ ++L+ + E
Sbjct: 1758 NMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKS 1817
Query: 909 -----LSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSV 963
++ EA + +L+E+ +QE R + AA + L+ + ++ E + +E +
Sbjct: 1818 KFKSTIAALEAKIAQLEEQVEQEAREKQ-----AATKSLKQKD-KKLKEILLQVEDERKM 1871
Query: 964 GSEFSSEL-------------AESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
++ + E A EE N ++ + E+DE E+++
Sbjct: 1872 AEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNE 1922
Score = 43.9 bits (102), Expect = 0.002
Identities = 42/193 (21%), Positives = 87/193 (45%), Gaps = 10/193 (5%)
Query: 788 LKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAE 847
L+K Q++L + ++ L E++++K + ++K + ER+R EAE
Sbjct: 1425 LEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE 1484
Query: 848 LRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQ 907
R ++ + + LE ++++E E T ++ K + V + K + +L++ K
Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1544
Query: 908 ELSLTEASLQ------KLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
E + E Q +LQ D +LR + +A + E ++ +E R ++R
Sbjct: 1545 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1604
Query: 961 LSVGSEFSSELAE 973
L E+ +EL +
Sbjct: 1605 L---HEYETELED 1614
Score = 41.2 bits (95), Expect = 0.011
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 24/156 (15%)
Query: 809 RQLLAEKREQEEKKKQEEEEKKKREEE-ERERERERREAELRAQQEEETRKQQELEALQK 867
R+LL E+ EEEEK K + + + E E E+R ++EE++R QELE L++
Sbjct: 1008 RKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSR--QELEKLKR 1065
Query: 868 ----------------SQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSL 911
+ AEL +L K++E Q + RL+ EI Q+ +++
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQA-ALARLDDEI--AQKNNALKKIRE 1122
Query: 912 TEASLQKLQERRDQE--LRRLEEEACRAAQEFLESL 945
E + LQE D E R E+ R E LE+L
Sbjct: 1123 LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 1158
Score = 40.0 bits (92), Expect = 0.024
Identities = 42/154 (27%), Positives = 75/154 (48%), Gaps = 15/154 (9%)
Query: 814 EKREQEEKKKQEEEEKKKREEEER-------ERERERREAELRAQQEEETRKQQELEALQ 866
E E+ +K+ Q+E E ++ EE+ E+ + R + EL + ++Q + L+
Sbjct: 1395 EALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLE 1454
Query: 867 KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
K Q++ + EK +K +E R E E R KE + LSL A + L+ + +E
Sbjct: 1455 KKQRKFDQLLAEEKNISSKYADERDRAEAE----AREKETKALSLARALEEALEAK--EE 1508
Query: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
L R + +A E L S + D++ + V +E+S
Sbjct: 1509 LER-TNKMLKAEMEDLVS-SKDDVGKNVHELEKS 1540
Score = 39.7 bits (91), Expect = 0.031
Identities = 88/372 (23%), Positives = 149/372 (40%), Gaps = 54/372 (14%)
Query: 684 KRYKVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVS 743
+R L NLA E+ T L +++ SE ++ K +KL+++ E + S
Sbjct: 1013 ERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDAS 1072
Query: 744 H-----AAMVIRAHVLGFLARKQYRKVLYCVV-----IIQKNYRAFLLRRRFLHLKKAAI 793
A + + L K+ ++ + I QKN +R H+
Sbjct: 1073 DFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISD--- 1129
Query: 794 VFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKRE----------EEERERERER 843
Q+ L + A R K E++++ EE E K E ++E +RE+
Sbjct: 1130 -LQEDLDSERAAR-------NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
Query: 844 REAELRAQQEEETRKQQELEALQKSQKEA----ELTRELEKQK-------ENKQV--EEI 890
L+ +EETR E + + QK A ELT +LE+ K +NKQ +E
Sbjct: 1182 EVTVLKKALDEETR-SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN 1240
Query: 891 LRLEKEIEDLQRMKEQQE--LSLTEASLQKLQER-RDQELRRLE-EEACRAAQEFLESLN 946
L E+ L + K++ E EA +Q+LQ + D E R E + Q +ES+
Sbjct: 1241 ADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVT 1300
Query: 947 --FDEIDECVRNIER---SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
+E + + + SLS + + EL + +K N + EEE + + D
Sbjct: 1301 GMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLD 1360
Query: 1002 DAFKDSPNPSEH 1013
+ + N H
Sbjct: 1361 EEMEAKQNLERH 1372
Score = 38.5 bits (88), Expect = 0.068
Identities = 56/219 (25%), Positives = 100/219 (45%), Gaps = 34/219 (15%)
Query: 809 RQLLAEKREQE----EKKKQEEEEKKKR-----EEEERERERERREAELRAQQEEETRKQ 859
++LL E+ Q+ K +Q EEE+ EE E ++ ER + L Q + +K
Sbjct: 1328 QELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKL 1387
Query: 860 QE----LEALQKS----QKEAE-LTRELEKQKE--NKQVEEILRLEKEIEDL-QRMKEQQ 907
Q+ +EAL++ QKE E LT++ E++ +K + RL++E++DL + Q+
Sbjct: 1388 QDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQR 1447
Query: 908 ELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEF 967
+L ++L+K Q + DQ L A ++ + S DE D +
Sbjct: 1448 QL---VSNLEKKQRKFDQLL---------AEEKNISSKYADERDRAEAEAREKETKALSL 1495
Query: 968 SSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKD 1006
+ L E A E K + + E+++ + DD K+
Sbjct: 1496 ARAL-EEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1533
Score = 37.7 bits (86), Expect = 0.12
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 16/119 (13%)
Query: 818 QEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELE--------ALQKSQ 869
Q+ ++ +EE ++K + R+ E L+ Q +EE +Q LE L S+
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSK 1384
Query: 870 KE-AELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927
K+ + +E +E K+ R +KEIE+L + E++ + + L+K + R QEL
Sbjct: 1385 KKLQDFASTVEALEEGKK-----RFQKEIENLTQQYEEKAAAYDK--LEKTKNRLQQEL 1436
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 497 bits (1279), Expect = e-140
Identities = 333/994 (33%), Positives = 548/994 (55%), Gaps = 71/994 (7%)
Query: 45 KQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVN 104
K++ + + M+P V+DMA LT L+ S+++NL RY IYTY G +N
Sbjct: 67 KKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVIN 126
Query: 105 PYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKT 164
PY+ + +Y +E Y + E+PPHI+AI+ YRC+ + ++Q IL +GESGAGKT
Sbjct: 127 PYKNLP-IYSENIIEMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKT 185
Query: 165 ESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224
E+TK ++++L+ ++ +ER +L+++PI+E+FGNAKTV N+NSSRFGKF
Sbjct: 186 ENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKF 245
Query: 225 VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPE 284
+++N G I G I YLLEK+R VRQ ER +HIFY LL+G + + L
Sbjct: 246 IRINFDVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFN 305
Query: 285 NYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF--- 341
NY +L+ +G + D+++F+E + AM +M FS EE+ + ++++ +L GNI F
Sbjct: 306 NYRFLS-NGYIPIPGQQDKDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKE 364
Query: 342 ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSL 401
A + T + LLG++ + T A+ + + + + +QA + ++L
Sbjct: 365 RNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQADFAVEAL 424
Query: 402 AMALYACCFEWVIKKINSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQ 459
A A Y F W++ +IN + + IGILDI GFE FE+N FEQ INY NEKLQ
Sbjct: 425 AKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQ 484
Query: 460 EYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL---GLLALINEESHFPQA 515
+ FN +F LEQ EY REG+ W ID+ +D C+DLIE+ G+LAL++EE FP+A
Sbjct: 485 QLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKA 544
Query: 516 TDSTLLEKLHSQHANNHFYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLL 573
TD T +EKL + ++ + KPR + +F + HYAG+V Y L KN D D++
Sbjct: 545 TDKTFVEKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVA 604
Query: 574 NLLRESRFDFIYDLFEHVSSRNNQDTL------KCGSKHRRP-----TVSSQFKDSLHSL 622
LL +S F+ +L++ V D + GS ++ TV +K+SL L
Sbjct: 605 TLLHQSSDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTKL 664
Query: 623 MATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDF 682
MATL ++NP FVRCI PN +K + D +VL+QLR +G+LE +RI + G+ R FQ+F
Sbjct: 665 MATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEF 724
Query: 683 YKRYKVLMRNLALPE---DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRRE 739
+RY++L N A+P+ D + C +++ + + +++G++K+F R + LE+ R+
Sbjct: 725 RQRYEILTPN-AIPKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERD 783
Query: 740 EEVSHAAMVIRAHVLGFLARKQYRK---VLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQ 796
+++ + +A G+LARK + K L + ++Q+N A+L R + + VF
Sbjct: 784 LKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWR----VFT 839
Query: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQ-EEE 855
K R +L A+ E + K+++ + + + EE ER+ ++ E + A+Q + E
Sbjct: 840 KVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAE 899
Query: 856 TRKQQELEALQ-----KSQKEAELTRELEKQ-KENKQVEEILRLEKE-----IEDLQRMK 904
T E E ++ K Q+ E+ +LE + +E ++ +IL+ EK+ I+DL+
Sbjct: 900 TELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQL 959
Query: 905 EQQELSLTEASLQKLQ-----ERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIER 959
+++E + + L+K+ ++ ++E+ LE++ + +E + L D I EC
Sbjct: 960 DEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE--KKLMEDRIAEC------ 1011
Query: 960 SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEV 993
SS+LAE EE+ N ++ ++EV
Sbjct: 1012 --------SSQLAE---EEEKAKNLAKIRNKQEV 1034
Score = 50.1 bits (118), Expect = 2e-05
Identities = 74/300 (24%), Positives = 135/300 (45%), Gaps = 39/300 (13%)
Query: 711 DASNSEWQLGKTKVF-LRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCV 769
D + +E + +TK L +LE+ LE + E E + + RA + ++ K
Sbjct: 1472 DRAEAEAREKETKALSLARALEEALEAKEEFERQNKQL--RADMEDLMSSKDD------- 1522
Query: 770 VIIQKNYRAFLLRRRFLHLKKAAIVFQ-KQLRGQIARRVYRQLLAEKREQEEKKKQEEEE 828
+ KN +R L + + Q ++L ++ +L E Q K + E +
Sbjct: 1523 --VGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDL 1580
Query: 829 KKKREE-EERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE--NK 885
+ + E+ EE++R ++ EL A+ E+E RKQ+ L K + E +L ++LE Q E NK
Sbjct: 1581 QTRDEQNEEKKRLLIKQVRELEAELEDE-RKQRALAVASKKKMEIDL-KDLEAQIEAANK 1638
Query: 886 QVEEIL----RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEF 941
+E++ +L+ +++D QR E+ S E Q + +++L+ LE E + +E
Sbjct: 1639 ARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQ--SKESEKKLKSLEAEILQLQEEL 1696
Query: 942 LESLNFDEIDECVRNIERSLSVGSEFSSELAESA------CEEKPNFNFSQPYPEEEVDE 995
S + R+ E+ E + E+ SA +EK EEE++E
Sbjct: 1697 ASS------ERARRHAEQE---RDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE 1747
Score = 45.4 bits (106), Expect = 6e-04
Identities = 41/144 (28%), Positives = 76/144 (52%), Gaps = 27/144 (18%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELE-ALQKS 868
E+R ++E+K ++E EK KR+ + + + + AEL+AQ +E +K++EL+ AL +
Sbjct: 1040 EERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG 1099
Query: 869 QKE------------------AELTRELEKQK--ENKQVEEILRLEKEIEDLQRMKEQQE 908
E AEL + E +K NK ++ L +E+E L+ E ++
Sbjct: 1100 DDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK--TELED 1157
Query: 909 LSLTEASLQKLQERRDQELRRLEE 932
T A+ Q+L+ +R+QE+ L++
Sbjct: 1158 TLDTTAAQQELRTKREQEVAELKK 1181
Score = 45.4 bits (106), Expect = 6e-04
Identities = 85/378 (22%), Positives = 160/378 (42%), Gaps = 61/378 (16%)
Query: 687 KVLMRNLALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAA 746
KVL + A E R K + +Q A SE LR L +K K + E + +
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDR------LRVELAEKASKLQNELDNVST 1294
Query: 747 MVIRAHVLGFLARKQYRKVLYCVV----IIQKNYRAFL---LRRRFLHLKKAAIVFQKQL 799
++ A G K + + ++Q+ R L R R L +K ++ Q++
Sbjct: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
Query: 800 RGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE---- 855
+ + + +Q+LA + + + KK+ +++ E E +++ ++AE +Q+ EE
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
Query: 856 --------TRKQQELEALQKS-QKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQ 906
R QQEL+ L + ++ LEK++ K+ +++L EK I R E+
Sbjct: 1415 YDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQ--KKFDQLLAEEKSIS--ARYAEE 1470
Query: 907 QELSLTEASLQKLQERRDQELRRLEEEACRAAQEF----------LESL--NFDEIDECV 954
++ + EA + +E + L R EEA A +EF +E L + D++ + V
Sbjct: 1471 RDRAEAEA---REKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNV 1527
Query: 955 RNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEHG 1014
+E+S + E+ EE+++ +A +DA K +
Sbjct: 1528 HELEKSKRALEQQVEEMRTQL---------------EELEDELQATEDA-KLRLEVNMQA 1571
Query: 1015 HSDQRTSGIRTSDDSSEE 1032
Q ++T D+ +EE
Sbjct: 1572 MKAQFERDLQTRDEQNEE 1589
Score = 45.1 bits (105), Expect = 7e-04
Identities = 47/196 (23%), Positives = 93/196 (47%), Gaps = 30/196 (15%)
Query: 796 QKQLRGQIARRV--YRQLLAEK-----REQEEKKKQEEEEKKKR-----------EEEER 837
Q+Q+ + ++ + QLLAE+ R EE+ + E E ++K E E
Sbjct: 1439 QRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 838 ERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE--NKQVEEILRLEK 895
+ E ER+ +LRA E+ + ++ + ELEK K +QVEE+ +
Sbjct: 1499 KEEFERQNKQLRADMEDLMSSKDDV---------GKNVHELEKSKRALEQQVEEMRTQLE 1549
Query: 896 EIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVR 955
E+ED + E +L L E ++Q ++ + +++L+ +E+ + ++ + E +
Sbjct: 1550 ELEDELQATEDAKLRL-EVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDE 1608
Query: 956 NIERSLSVGSEFSSEL 971
+R+L+V S+ E+
Sbjct: 1609 RKQRALAVASKKKMEI 1624
Score = 45.1 bits (105), Expect = 7e-04
Identities = 60/262 (22%), Positives = 106/262 (40%), Gaps = 58/262 (22%)
Query: 795 FQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELR----- 849
+Q++L + AR ++ A+ +E E+K K E E + +EE ER RR AE
Sbjct: 1657 YQREL--EEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELA 1714
Query: 850 ------------------------AQQEEETRKQQE----------LEALQKSQKEAELT 875
AQ EEE ++Q LQ AEL
Sbjct: 1715 DEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELA 1774
Query: 876 RELE--------KQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQEL 927
E +Q+ +Q +E+ +E+E + K + +S EA + +L+E+ +QE
Sbjct: 1775 AERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEA 1834
Query: 928 --RRLEEEACRAAQEFLESLNFD------EIDECVRNIERSLSVGSEFSSELAESACEEK 979
R + R ++ L+ + D+ +E++ + + +L E A EE
Sbjct: 1835 KERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL-EEAEEEA 1893
Query: 980 PNFNFSQPYPEEEVDEGFEADD 1001
N S+ + E+D+ EA++
Sbjct: 1894 TRANASRRKLQRELDDATEANE 1915
Score = 44.7 bits (104), Expect = 0.001
Identities = 53/243 (21%), Positives = 105/243 (43%), Gaps = 56/243 (23%)
Query: 796 QKQLRGQIAR------------RVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERER 843
+++L+G +AR +V R+L A+ E +E + E+ + K E+++R+
Sbjct: 1089 EEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLS--- 1145
Query: 844 REAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIED---- 899
+ELEAL+ ++ T +++ K+ +E+ L+K +E+
Sbjct: 1146 ----------------EELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKN 1189
Query: 900 ----LQRMKEQQELSLTEASLQKLQERR-----DQELRRLE----EEACRAAQEFLESLN 946
+Q M+++ +L E S Q Q +R ++ + LE E AC + L+ +
Sbjct: 1190 HEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEV--KVLQQVK 1247
Query: 947 FD------EIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEAD 1000
+ ++D V+ + +S G ELAE A + + + EE +G +
Sbjct: 1248 AESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFA 1307
Query: 1001 DDA 1003
DA
Sbjct: 1308 KDA 1310
Score = 42.0 bits (97), Expect = 0.006
Identities = 81/355 (22%), Positives = 158/355 (44%), Gaps = 47/355 (13%)
Query: 672 GYAVRRPF---QDFYKRYKVLMRNLALPEDVRG--------KCTSLLQLYDASNSEWQLG 720
GY R+ F Q KVL RN A +R K LLQ+ E Q
Sbjct: 799 GYLARKAFAKKQQQLSALKVLQRNCAAYLKLRHWQWWRVFTKVKPLLQV-TRQEEELQAK 857
Query: 721 KTKVFLRESLEQKLEKRREE-EVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAF 779
++ + + K+E EE E H ++ ++L + Q L+ + RA
Sbjct: 858 DEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILA--EQLQAETELFAEA---EEMRAR 912
Query: 780 LLRRR-----FLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREE 834
L ++ LH ++ + +++ R QI + +++ A ++ EE+ +EE ++K +
Sbjct: 913 LAAKKQELEEILHDLESRVEEEEE-RNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQL 971
Query: 835 EE--RERERERREAELRAQQEEETR--KQQELEALQKSQKEAELTRELEKQK-----ENK 885
E+ E + ++ E E+ +++ ++ K+++L + ++ ++L E EK K NK
Sbjct: 972 EKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNK 1031
Query: 886 Q-------VEEILRLEKEIEDLQRMKEQQELSLTE-----ASLQKLQERRDQELRRLEEE 933
Q E + + EK ++L++ K + + T+ A LQ + +L + EEE
Sbjct: 1032 QEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEE 1091
Query: 934 ACRA-AQEFLESLNFDEIDECVRNIERSLS-VGSEFSSELAESACEEKPNFNFSQ 986
A A+ E+L+ + + VR ++ ++ + +F SE A EK + S+
Sbjct: 1092 LQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSE 1146
Score = 41.6 bits (96), Expect = 0.008
Identities = 46/172 (26%), Positives = 84/172 (48%), Gaps = 22/172 (12%)
Query: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREA--------- 846
Q + + ++ + R+L AE ++ +++ KKK E + ++ E + A
Sbjct: 1586 QNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIK 1645
Query: 847 ELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVE-EILRLEKEIEDLQRMK- 904
+LR Q + Q+ELE + S+ E + E +K+ K +E EIL+L++E+ +R +
Sbjct: 1646 QLRKLQAQMKDYQRELEEARASRDEI-FAQSKESEKKLKSLEAEILQLQEELASSERARR 1704
Query: 905 ----EQQELS--LTEASLQK---LQERRDQELRRLE-EEACRAAQEFLESLN 946
E+ EL+ +T ++ K L E+R E R + EE Q +E LN
Sbjct: 1705 HAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLN 1756
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 496 bits (1276), Expect = e-139
Identities = 331/959 (34%), Positives = 530/959 (55%), Gaps = 59/959 (6%)
Query: 45 KQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVN 104
K+ + + M+P V+DMA LT L+ S+++NL +RY IYTY G +N
Sbjct: 63 KKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVIN 122
Query: 105 PYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKT 164
PY+ + +Y +E Y + E+PPHI+AI + YR + + ++Q IL +GESGAGKT
Sbjct: 123 PYKNLP-IYSEEIVEMYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKT 181
Query: 165 ESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224
E+TK ++++L+ ++ K+ +ER +L+++PI+EAFGNAKTV N+NSSRFGKF
Sbjct: 182 ENTKKVIQYLAYVASSHKS---KKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKF 238
Query: 225 VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPE 284
+++N G I G I YLLEK+R +RQ ER +HIFY LL+G + + L
Sbjct: 239 IRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYN 298
Query: 285 NYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF--- 341
Y +L+ +G V D++ F+E + AM +M +EE + R+++G+L LGNI F
Sbjct: 299 KYRFLS-NGHVTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKE 357
Query: 342 ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSL 401
A + TA + + LLG++ T T + + + + + +QA + ++L
Sbjct: 358 RNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQADFAIEAL 417
Query: 402 AMALYACCFEWVIKKINSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQ 459
A A Y F W++ +IN + + IGILDI GFE F++N FEQ INY NEKLQ
Sbjct: 418 AKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQ 477
Query: 460 EYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL---GLLALINEESHFPQA 515
+ FN +F LEQ EY REG+ W ID+ +D C+DLIEK G+LAL++EE FP+A
Sbjct: 478 QLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKA 537
Query: 516 TDSTLLEKLHSQHANNHFYVKPRVAVN--NFGVKHYAGEVQYDVRGILEKNRDTFRDDLL 573
TD + +EK+ + + + KP+ + +F + HYAG+V Y L KN D D++
Sbjct: 538 TDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIA 597
Query: 574 NLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRP-----------TVSSQFKDSLHSL 622
LL +S F+ +L++ V D + S+ P TV +K+ L L
Sbjct: 598 TLLHQSSDKFVSELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKL 657
Query: 623 MATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDF 682
MATL ++NP FVRCI PN +K + D +VL+QLR +G+LE +RI + G+ R FQ+F
Sbjct: 658 MATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEF 717
Query: 683 YKRYKVLMRNLALPE---DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRRE 739
+RY++L N ++P+ D + C +++ + ++ +++G++KVF R + LE+ R+
Sbjct: 718 RQRYEILTPN-SIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERD 776
Query: 740 EEVSHAAMVIRAHVLGFLARKQYRK---VLYCVVIIQKNYRAFLLRR-----RFLHLKKA 791
+++ + +A G+LARK + K L + ++Q+N A+L R R K
Sbjct: 777 LKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKP 836
Query: 792 AIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEE--EKKKREEEERERERERREAELR 849
+ +Q +A+ + EK+ E + E E + + E+ + +E+ + E EL
Sbjct: 837 LLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELC 896
Query: 850 AQQEE----ETRKQQELEAL-----QKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL 900
A+ EE T K+QELE + + ++E E + L+ +K+ Q + I LE+++E+
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQ-QNIQELEEQLEEE 955
Query: 901 Q--RMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNI 957
+ R K Q E TEA L+KL+E E LE++ C+ A+E + L D I E N+
Sbjct: 956 ESARQKLQLEKVTTEAKLKKLEE----EQIILEDQNCKLAKE--KKLLEDRIAEFTTNL 1008
Score = 49.3 bits (116), Expect = 4e-05
Identities = 49/199 (24%), Positives = 94/199 (47%), Gaps = 26/199 (13%)
Query: 787 HLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREA 846
H +++A +K+ ++ + QLLAE++ K +E + E RE+E +
Sbjct: 1431 HQRQSACNLEKK------QKKFDQLLAEEKTISAKYAEERDRA-----EAEAREKETKAL 1479
Query: 847 ELRAQQEEETRKQQELEALQK----------SQKE--AELTRELEKQKE--NKQVEEILR 892
L EE ++ ELE L K S K+ + ELEK K +QVEE+
Sbjct: 1480 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 1539
Query: 893 LEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDE 952
+E+ED + E +L L E +LQ ++ + +++L+ +E++ ++ + + E +
Sbjct: 1540 QLEELEDELQATEDAKLRL-EVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAEL 1598
Query: 953 CVRNIERSLSVGSEFSSEL 971
+RS++V + E+
Sbjct: 1599 EDERKQRSMAVAARKKLEM 1617
Score = 48.5 bits (114), Expect = 7e-05
Identities = 47/168 (27%), Positives = 75/168 (44%), Gaps = 26/168 (15%)
Query: 817 EQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQ------------QELEA 864
E+EEK K + K K E + E R E + Q+ E+TR++ EL+A
Sbjct: 1010 EEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQA 1069
Query: 865 ------LQKSQKEAELTREL-----EKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTE 913
+Q ++KE EL L E ++N +++I LE +I +LQ E + S +
Sbjct: 1070 QIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNK 1129
Query: 914 ASLQKLQERRDQELRRLEEE---ACRAAQEFLESLNFDEIDECVRNIE 958
A QK + E + E E AAQ+ L S E++ + +E
Sbjct: 1130 AEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLE 1177
Score = 47.0 bits (110), Expect = 2e-04
Identities = 53/240 (22%), Positives = 100/240 (41%), Gaps = 37/240 (15%)
Query: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERE---------RERERREA 846
+K+L+ A + QL E E K+Q ++E+ + +E E+ R EA
Sbjct: 1672 EKKLKSMEAEMI--QLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEA 1729
Query: 847 ELRAQQEEETRKQQELEALQKSQKEAEL-----------------TRELEKQKENKQVEE 889
+ +EE +Q E + K+A L E +Q+ +Q +E
Sbjct: 1730 RIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKE 1789
Query: 890 ILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLN--F 947
+ +E+E + K + ++ EA + +L+E+ D E + + AC+ + + L
Sbjct: 1790 LKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKE-RQAACKQVRRTEKKLKDVL 1848
Query: 948 DEIDECVRNIERSLSVGSEFSSEL------AESACEEKPNFNFSQPYPEEEVDEGFEADD 1001
++D+ RN E+ + S+ L E A EE N S+ + E+++ E D
Sbjct: 1849 LQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETAD 1908
Score = 46.6 bits (109), Expect = 3e-04
Identities = 40/175 (22%), Positives = 85/175 (48%), Gaps = 10/175 (5%)
Query: 798 QLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR 857
+L+ QIA + E+ Q + EEE +K ++ RE E + +EL+ E E
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 858 KQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQ 917
+ + E +++ +L ELE K ++E+ L ++L R K +QE+++ + +L+
Sbjct: 1126 SRNKAE-----KQKRDLGEELEALK--TELEDTLDSTAAQQEL-RSKREQEVNILKKTLE 1177
Query: 918 KLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELA 972
+ + + +++ + ++ +A +E E L ++ N+E++ ELA
Sbjct: 1178 EEAKTHEAQIQEMRQKHSQAVEELAEQL--EQTKRVKANLEKAKQTLENERGELA 1230
Score = 45.8 bits (107), Expect = 4e-04
Identities = 41/137 (29%), Positives = 63/137 (45%), Gaps = 12/137 (8%)
Query: 810 QLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQ 869
++LA+ +E E+K K E E + +EE ER +R+A QQE + + + K
Sbjct: 1663 EILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQA----QQERDELADEIANSSGKGA 1718
Query: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRR 929
E R LE + I +LE+E+E+ Q E L +A+LQ Q D L R
Sbjct: 1719 LALEEKRRLEAR--------IAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLER 1770
Query: 930 LEEEACRAAQEFLESLN 946
+ A++ LE N
Sbjct: 1771 SHAQKNENARQQLERQN 1787
Score = 43.5 bits (101), Expect = 0.002
Identities = 42/192 (21%), Positives = 86/192 (44%), Gaps = 31/192 (16%)
Query: 786 LHLKKAAIVFQKQLRG--QIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERER 843
++L+ F++ L+G + + +QL+ + RE E + + E +++ ++ E +
Sbjct: 1560 VNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDL 1619
Query: 844 REAELRAQQEEETRKQ--QELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIE--- 898
++ E + R + ++L LQ K+ REL+ + ++ EEIL KE E
Sbjct: 1620 KDLEAHIDSANKNRDEAIKQLRKLQAQMKDC--MRELDDTRASR--EEILAQAKENEKKL 1675
Query: 899 ---DLQRMKEQQELSLTEASLQKLQERRD-----------------QELRRLEEEACRAA 938
+ + ++ Q+EL+ E + ++ Q+ RD +E RRLE +
Sbjct: 1676 KSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLE 1735
Query: 939 QEFLESLNFDEI 950
+E E E+
Sbjct: 1736 EELEEEQGNTEL 1747
Score = 43.1 bits (100), Expect = 0.003
Identities = 42/186 (22%), Positives = 80/186 (43%), Gaps = 20/186 (10%)
Query: 815 KREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAEL 874
+R+ + + +Q EE+KK+ + RE E E + + RK+ E++ K+ E
Sbjct: 1570 ERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDL-----KDLEA 1624
Query: 875 TRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERR-----DQELRR 929
+ + ++ ++++ +L+ +++D R + S E Q + + + E+ +
Sbjct: 1625 HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQ 1684
Query: 930 LEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYP 989
L+EE AA E + E DE I S G+ A EEK
Sbjct: 1685 LQEEL--AAAERAKRQAQQERDELADEIANSSGKGA--------LALEEKRRLEARIAQL 1734
Query: 990 EEEVDE 995
EEE++E
Sbjct: 1735 EEELEE 1740
Score = 42.0 bits (97), Expect = 0.006
Identities = 40/154 (25%), Positives = 72/154 (46%), Gaps = 15/154 (9%)
Query: 814 EKREQEEKKKQEEEEKKKREEEER-------ERERERREAELRAQQEEETRKQQELEALQ 866
E E+ ++K Q++ E + EE+ E+ + R + EL + ++Q L+
Sbjct: 1381 ETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLE 1440
Query: 867 KSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQE 926
K QK+ + EK K EE R E E R KE + LSL A + ++++ E
Sbjct: 1441 KKQKKFDQLLAEEKTISAKYAEERDRAEAE----AREKETKALSLARALEEAMEQK--AE 1494
Query: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERS 960
L RL ++ ++ + S D++ + V +E+S
Sbjct: 1495 LERLNKQFRTEMEDLMSSK--DDVGKSVHELEKS 1526
Score = 37.4 bits (85), Expect = 0.15
Identities = 49/226 (21%), Positives = 93/226 (41%), Gaps = 32/226 (14%)
Query: 728 ESLEQKLEKRREE------EVSHAAMVIRAHVLGF---LARKQYRKVLYCVVIIQKNYRA 778
E Q+LEK R + ++S ++A + LA+K+ + ++ +
Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099
Query: 779 FLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKRE----- 833
+ ++ L+ Q+ L + A R K E++++ EE E K E
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASR-------NKAEKQKRDLGEELEALKTELEDTL 1152
Query: 834 -----EEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVE 888
++E +RE+ L+ EEE K E + + QK ++ EL +Q+E
Sbjct: 1153 DSTAAQQELRSKREQEVNILKKTLEEEA-KTHEAQIQEMRQKHSQAVEELA-----EQLE 1206
Query: 889 EILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEA 934
+ R++ +E ++ E + L LQ + D E +R + EA
Sbjct: 1207 QTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEA 1252
Score = 37.4 bits (85), Expect = 0.15
Identities = 43/189 (22%), Positives = 84/189 (44%), Gaps = 12/189 (6%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAE 873
E + Q+ ++ +EE ++K + ++ E + R Q EEE + LE Q + A+
Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEK-QIATLHAQ 1365
Query: 874 LTRELEKQKEN----KQVEEILR-LEKEIEDLQRMKEQQELSL--TEASLQKLQERRDQE 926
+ +K +++ + EE+ R L+K++E L + E++ + E + +LQ+ D
Sbjct: 1366 VADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL 1425
Query: 927 LRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQ 986
L L+ + A + FD++ E+++S + AE+ EK S
Sbjct: 1426 LVDLDHQRQSACNLEKKQKKFDQL----LAEEKTISAKYAEERDRAEAEAREKETKALSL 1481
Query: 987 PYPEEEVDE 995
EE E
Sbjct: 1482 ARALEEAME 1490
Score = 34.3 bits (77), Expect = 1.3
Identities = 44/183 (24%), Positives = 81/183 (44%), Gaps = 21/183 (11%)
Query: 813 AEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEA 872
A ++E K++QE KK EE E + EA+++ +++ ++ +EL + K
Sbjct: 1156 AAQQELRSKREQEVNILKKTLEE----EAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRV 1211
Query: 873 ELTRELEKQK-ENKQVEEILRLEKEIEDLQRMK--EQQELSLTEASLQKLQERRDQELRR 929
+ E KQ EN++ E L E++ L + K + + EA LQ+LQ + ++ R
Sbjct: 1212 KANLEKAKQTLENERGE----LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERV 1267
Query: 930 LEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYP 989
E A + + +E + N+ LS SS+L + + +Q
Sbjct: 1268 RTELADKVTKLQVE----------LDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELL 1317
Query: 990 EEE 992
+EE
Sbjct: 1318 QEE 1320
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
[Homo sapiens]
Length = 1937
Score = 495 bits (1275), Expect = e-139
Identities = 323/965 (33%), Positives = 542/965 (56%), Gaps = 50/965 (5%)
Query: 5 FTEGTRVWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEE 63
F T V++ E + + ST+ S G V +T+ G T ++ +V M+P +
Sbjct: 34 FDAKTSVFVAEPKESYVKSTIQSKEGGKVTVKTEGGATLTVRED-----QVFPMNPPKYD 88
Query: 64 GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123
++DMA +T LH ++YNL +RY IYTY G +VNPY+ + +Y+P + Y
Sbjct: 89 KIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVAAYRG 147
Query: 124 RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVIS---QQ 180
+ E PPHIF+I++ Y+ + +NQ ILI+GESGAGKT +TK ++++ + I+ ++
Sbjct: 148 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 207
Query: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240
+ S K + + +E I+ ++P++EAFGNAKTV N+NSSRFGKF++++ G + I
Sbjct: 208 KKDESGKMQGT-LEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADI 266
Query: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDKT 299
YLLEK+RV Q ER+YHIFY + + + + E ++T P +Y +++Q G + +
Sbjct: 267 ETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQ-GEITVPS 325
Query: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALG 356
I DQE +A+D++ F+ EE + +L ++H GN++F A+
Sbjct: 326 IDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVAD 385
Query: 357 RSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKK 416
++A L L+ L AL + + E + VQQ ++ +LA A+Y F W++ +
Sbjct: 386 KAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTR 445
Query: 417 INSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYS 475
IN ++ + + IG+LDI GFE F+ N EQ IN+ NEKLQ++FN H+F LEQ EY
Sbjct: 446 INQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYK 505
Query: 476 REGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNHF 533
+EG+ W ID+ +D C++LIEK LG+ +++ EE FP+ATD++ KL+ QH +
Sbjct: 506 KEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSAN 565
Query: 534 YVKPRV----AVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFE 589
+ KP+V A +F + HYAG V Y++ G L+KN+D D ++ L ++S + LF
Sbjct: 566 FQKPKVVKGKAEAHFSLIHYAGTVDYNITGWLDKNKDPLNDTVVGLYQKSAMKTLASLFS 625
Query: 590 HVSSRNNQDTLKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPD 646
+S + K G+K + TVS+ F+++L+ LM L S++P FVRCI PN K P
Sbjct: 626 TYASAEADSSAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPG 685
Query: 647 QFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----DVRGK 702
+ +VL+QLR +G+LE +RI + G+ R + DF +RYKVL + A+PE D +
Sbjct: 686 AMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNAS-AIPEGQFIDSKKA 744
Query: 703 CTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQY 762
LL D +++++ G TKVF + L LE+ R+E+++ +A GFL R +Y
Sbjct: 745 SEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFLMRVEY 804
Query: 763 RKVLY---CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQE 819
+K+L + IQ N RAF+ + + +K +F K ++ + + +A +E+
Sbjct: 805 QKMLQRREALFCIQYNVRAFMNVKHWPWMK----LFFK-IKPLLKSAETEKEMATMKEEF 859
Query: 820 EKKKQE----EEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQ----KSQKE 871
+K K E E ++K+ EE+ +E+ + +L+ Q E ++ E Q K Q E
Sbjct: 860 QKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE 919
Query: 872 AELTRELEKQKENKQVE-EILRLEKEIED--LQRMKEQQELSLTEASLQKLQERRDQELR 928
A++ E+ +E +++ E+ ++++ED + K+ +L LT A ++K + + +++
Sbjct: 920 AKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 979
Query: 929 RLEEE 933
L EE
Sbjct: 980 NLTEE 984
Score = 50.1 bits (118), Expect = 2e-05
Identities = 70/296 (23%), Positives = 133/296 (44%), Gaps = 47/296 (15%)
Query: 680 QDFYKRYKVLMRNLALPEDVRGKCTSLLQ---------------LYDASNSEWQLGKTKV 724
++F K L ++ A +++ K +LL+ L DA QL K K+
Sbjct: 857 EEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKI 916
Query: 725 FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKVLYCVVIIQKNYRAFLL 781
L +++ E+ EEE +A + + L +K + + ++K A
Sbjct: 917 QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976
Query: 782 RRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEK--------KKQEEE--- 827
+ + L + A + + + + + ++Q L + + +E+K K E++
Sbjct: 977 KVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDD 1036
Query: 828 -----EKKKREEEERERERERREAELRAQQEE----ETRKQQELEALQKSQKEAELTREL 878
E++K+ + ER + + E +L+ QE E KQQ E L+K KE E++ +
Sbjct: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEK--KEFEISNLI 1094
Query: 879 EKQKENKQVEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQERRDQELRRLEE 932
K E++Q EI +L+K+I++LQ E+ +E+ AS K +++R R LEE
Sbjct: 1095 SKI-EDEQAVEI-QLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEE 1148
Score = 45.1 bits (105), Expect = 7e-04
Identities = 45/206 (21%), Positives = 101/206 (49%), Gaps = 22/206 (10%)
Query: 805 RRVYRQLLAEKR----EQEEKKKQEEEEKKKREEEERERERERREAE-LRAQQEEETRKQ 859
+R+ L A++ E E +Q +E+ + R ++ ++ E L+ Q EEET+ +
Sbjct: 1270 QRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAK 1329
Query: 860 QEL-EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQK 918
L ALQ S+ + +L RE ++++ + E L K ++ + + + E + + ++
Sbjct: 1330 NALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRT-EE 1388
Query: 919 LQERRDQELRRLEEEACRAAQEFLESLN-----FDEIDECVRNIERSLSVGSEFSSELAE 973
L+E + + +RL+E A+E +E++N ++ + ++N L + E S+
Sbjct: 1389 LEEAKKKLAQRLQE-----AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACA 1443
Query: 974 SACEEKPNFN-----FSQPYPEEEVD 994
+ +++ NF+ + Q Y E + +
Sbjct: 1444 ALDKKQRNFDKVLSEWKQKYEETQAE 1469
Score = 42.7 bits (99), Expect = 0.004
Identities = 48/232 (20%), Positives = 98/232 (42%), Gaps = 38/232 (16%)
Query: 800 RGQIARRVYRQLLAEKREQEEKKKQEEEE---------KKKREEEERERERERREAELRA 850
R + + +L A+KR+ E++ + +++ K ++E+ E + + E+
Sbjct: 928 RAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 987
Query: 851 QQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELS 910
E + +E +ALQ++ ++ + E+ K N + +LE++++DL+ EQ++
Sbjct: 988 LDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEK-- 1045
Query: 911 LTEASLQKLQERRDQELRRLEEEAC------RAAQEFLESLNFDEIDECVRNIE------ 958
L++ + + + +L+ +E + E LE F EI + IE
Sbjct: 1046 KLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEF-EISNLISKIEDEQAVE 1104
Query: 959 ------------RSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFE 998
R +G E +E A A EK + S+ EE+ E E
Sbjct: 1105 IQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSREL--EEISERLE 1154
Score = 42.4 bits (98), Expect = 0.005
Identities = 30/124 (24%), Positives = 60/124 (48%), Gaps = 9/124 (7%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
E R +E + + E E+K+ E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
Query: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRR 929
K + E +++ N + + +L+ E+E+ ++ + E+ + KL+ + + +
Sbjct: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEE-----AEERADIAESQVNKLRVKSREVHTK 1933
Query: 930 LEEE 933
+ E
Sbjct: 1934 ISAE 1937
Score = 42.0 bits (97), Expect = 0.006
Identities = 46/202 (22%), Positives = 94/202 (46%), Gaps = 27/202 (13%)
Query: 810 QLLAEKREQEEKKKQEEE-------EKKKREEEERERERERREAELRAQQEEETRKQQEL 862
QL A+ +E E+ ++EEE +K+K E+E E +++ + EL + E+ + E
Sbjct: 917 QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATEN 976
Query: 863 EALQKSQKEAELTRELEK-QKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQE 921
+ +++ A L + K KE K ++E ++ ++DLQ E+ ++++ + KL++
Sbjct: 977 KVKNLTEEMAGLDETIAKLSKEKKALQE--THQQTLDDLQ--AEEDKVNILTKAKTKLEQ 1032
Query: 922 RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACE---- 977
+ D LE+E + L D ++ R +E L + E + ++ +
Sbjct: 1033 QVDDLEGSLEQE---------KKLRMD-LERAKRKLEGDLKLAQESTMDMENDKQQLDEK 1082
Query: 978 -EKPNFNFSQPYPEEEVDEGFE 998
EK F S + E ++ E
Sbjct: 1083 LEKKEFEISNLISKIEDEQAVE 1104
Score = 41.6 bits (96), Expect = 0.008
Identities = 78/351 (22%), Positives = 141/351 (40%), Gaps = 52/351 (14%)
Query: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEE-------KKKREEEERERERERREAEL 848
+++L G + + E +Q+ +K E++E K +E+ E + +++ EL
Sbjct: 1055 KRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKEL 1114
Query: 849 RAQQEEETRKQQELEALQKSQKEAE-----LTRELEKQKENKQVEEILRLEKEIEDLQRM 903
+A+ EE +E+EA + S+ +AE L+RELE+ E ++EE +L +
Sbjct: 1115 QARIEE---LGEEIEAERASRAKAEKQRSDLSRELEEISE--RLEEAGGATSAQVELNKK 1169
Query: 904 KEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIER---- 959
+ EA QKL RRD E L+ EA AA + + E+ E + N++R
Sbjct: 1170 R--------EAEFQKL--RRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQK 1219
Query: 960 ------SLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSEH 1013
L + ++ S AE+ + K N E++V E K +
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSE--------LKTKEEEQQR 1271
Query: 1014 GHSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGESTY 1073
+D R ++ E +++ S + S +++ E T
Sbjct: 1272 LINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEEL----KHQLEEETK 1327
Query: 1074 CMPQNAGDLPSPDGDYDYDQDDYE---DGAITSGSSVTFSNSYGSQWSPDY 1121
A L S D D ++ YE +G +++ +NS +QW Y
Sbjct: 1328 AKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKY 1378
Score = 38.1 bits (87), Expect = 0.089
Identities = 38/150 (25%), Positives = 75/150 (50%), Gaps = 18/150 (12%)
Query: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELTRELEKQK 882
+KK+R + E +++ E +AEL A Q+E EL ++ +E+ + L ++
Sbjct: 1446 DKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRREN 1505
Query: 883 ENKQ------VEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQ---ERRDQELRRLE 931
+N Q E+I K+I +L+++K+Q QE +A+L++ + E + ++ R++
Sbjct: 1506 KNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQ 1565
Query: 932 EEACRAAQEFLESL--NFDEIDECVRNIER 959
E + E + +EID+ RN R
Sbjct: 1566 LELNQVKSEVDRKIAEKDEEIDQLKRNHTR 1595
Score = 33.1 bits (74), Expect = 2.9
Identities = 41/175 (23%), Positives = 76/175 (43%), Gaps = 29/175 (16%)
Query: 804 ARRVYRQLLAEKREQEEKKKQEE---EEKKKREEEERERERERREAELRAQQEEETRKQQ 860
+R + +L K EE Q E E K ++E + + E + + E+ +KQ
Sbjct: 1477 SRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQV 1536
Query: 861 ELEA--LQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQK 918
E E +Q + +EAE + E E+ K ILR++ E L ++K + + + E
Sbjct: 1537 EQEKCEIQAALEEAEASLEHEEGK-------ILRIQLE---LNQVKSEVDRKIAE----- 1581
Query: 919 LQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAE 973
+D+E+ +L+ R + +L D +R+ +L V + +L E
Sbjct: 1582 ----KDEEIDQLKRNHTRVVETMQSTL-----DAEIRSRNDALRVKKKMEGDLNE 1627
Score = 33.1 bits (74), Expect = 2.9
Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 10/102 (9%)
Query: 826 EEEKKKREEEERERERERREAELRAQQEEE--TRKQQELEALQK--SQKEAELTRELEKQ 881
E+ KK+ E+E+ E + EAE + EE R Q EL ++ +K AE E+++
Sbjct: 1530 EKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQL 1589
Query: 882 KEN-KQVEEILR--LEKEI---EDLQRMKEQQELSLTEASLQ 917
K N +V E ++ L+ EI D R+K++ E L E +Q
Sbjct: 1590 KRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQ 1631
Score = 31.6 bits (70), Expect = 8.4
Identities = 32/141 (22%), Positives = 58/141 (41%), Gaps = 14/141 (9%)
Query: 817 EQEEKKKQEEEEKKKREEEER---------ERERERREAELRAQQEEETRKQQELEALQK 867
E EE KK+ + ++ EE E+ ++R + E+ + R AL K
Sbjct: 1388 ELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK 1447
Query: 868 SQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ----RMKEQQELSLTE-ASLQKLQER 922
Q+ + KQK + E+ +KE L ++K E SL + +L++ +
Sbjct: 1448 KQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKN 1507
Query: 923 RDQELRRLEEEACRAAQEFLE 943
QE+ L E+ ++ E
Sbjct: 1508 LQQEISDLTEQIAEGGKQIHE 1528
Score = 31.6 bits (70), Expect = 8.4
Identities = 50/226 (22%), Positives = 98/226 (43%), Gaps = 28/226 (12%)
Query: 782 RRRFLHLKKAAIV-FQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840
R + LH + +++ +K+L +++ L + E+ ++ + EEK K+ +
Sbjct: 1715 RVQLLHTQNTSLINTKKKLENDVSQ------LQSEVEEVIQESRNAEEKAKKAITDAAMM 1768
Query: 841 RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL 900
E + E E K+ + ++ Q + +L + KQ++ +LE + +L
Sbjct: 1769 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQ---KLEARVREL 1825
Query: 901 QRMKEQQELSLTEA--SLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIE 958
+ E ++ EA L+K ERR +EL EE + + + D++ V++ +
Sbjct: 1826 EGEVENEQKRNAEAVKGLRK-HERRVKELTYQTEEDRKNVLRLQDLV--DKLQAKVKSYK 1882
Query: 959 RSLSVGSEFSSELAESACEEKPNFNFSQ-PYPEEEVDEGFEADDDA 1003
R AE A EE+ N N S+ + E++E E D A
Sbjct: 1883 RQ-----------AEEA-EEQSNANLSKFRKLQHELEEAEERADIA 1916
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 491 bits (1265), Expect = e-138
Identities = 330/1058 (31%), Positives = 562/1058 (53%), Gaps = 59/1058 (5%)
Query: 5 FTEGTRVWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEE 63
F T V++ E + F T+ S G V +T+ G T K +V M+P +
Sbjct: 32 FDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGATLTVKDD-----QVFPMNPPKYD 86
Query: 64 GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123
++DMA +T LH +++YNL +RY IYTY G +VNPY+ + +Y+P + Y
Sbjct: 87 KIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVTAYRG 145
Query: 124 RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVIS----Q 179
+ E PPHIF+I++ Y+ + +NQ ILI+GESGAGKT +TK ++++ + I+ +
Sbjct: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205
Query: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
+ E++ + +E I+ ++P++EAFGNAKTV N+NSSRFGKF++++ G +
Sbjct: 206 KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
Query: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDK 298
I YLLEK+RVV Q ER+YHIFY + + + E E ++T P +Y +++Q G +
Sbjct: 266 IETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ-GEISVA 324
Query: 299 TISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTAL 355
+I DQE +A+D++ F+ EE + +L ++H GN++F A+
Sbjct: 325 SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVA 384
Query: 356 GRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIK 415
++A L L+ L AL + + E + V+Q ++ +LA A+Y F W++
Sbjct: 385 DKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVA 444
Query: 416 KINSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEY 474
+IN ++ + + IG+LDI GFE F+ N EQ IN+ NEKLQ++FN H+F LEQ EY
Sbjct: 445 RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
Query: 475 SREGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNH 532
+EG+ W ID+ +D C++LIEK +G+ +++ EE FP+ATD++ KL+ QH +
Sbjct: 505 KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSA 564
Query: 533 FYVKPRV----AVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF 588
+ KP+V A +F + HYAG V Y++ G LEKN+D + ++ L ++S + LF
Sbjct: 565 NFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF 624
Query: 589 EHVSSRNNQDT---LKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQ 642
+ + K G K + TVS+ F+++L+ LM L S++P FVRCI PN
Sbjct: 625 SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684
Query: 643 KMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----D 698
K P + +VL+QLR +G+LE +RI + G+ R + DF +RYKVL + A+PE D
Sbjct: 685 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNAS-AIPEGQFID 743
Query: 699 VRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA 758
+ LL D +++++ G TKVF + L LE+ R+++++ +A GFLA
Sbjct: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803
Query: 759 RKQYRKVL---YCVVIIQKNYRAFL------LRRRFLHLKKAAIVFQKQLRGQIARRVYR 809
R +Y++++ + IQ N R+F+ + F +K + + + ++
Sbjct: 804 RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863
Query: 810 QLLAEKREQEEKKKQEEE-------EKKKREEEERERERERREAELRAQQEEETRKQQEL 862
++ E + E K+K+ EE EK + + + +AE R Q +T+ Q E
Sbjct: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923
Query: 863 ---EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ--RMKEQQELSLTEASLQ 917
E ++++ E E+ EL K+ K +E L+K+I+DL+ K ++E TE ++
Sbjct: 924 KIKEVTERAEDEEEINAEL-TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982
Query: 918 KLQERR---DQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAES 974
L E D+ + +L +E + ++L+ + +E N + E + E
Sbjct: 983 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1042
Query: 975 ACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSE 1012
+ E++ + +++ + ++ D N +
Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Score = 48.1 bits (113), Expect = 9e-05
Identities = 63/252 (25%), Positives = 121/252 (48%), Gaps = 32/252 (12%)
Query: 709 LYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKV 765
L DA QL KTK+ L +++ E+ +EE +A + + L +K +
Sbjct: 904 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 766 LYCVVIIQKNYRAFLLRRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEKK 822
+ ++K A + + L + A + + + + + ++Q L + + +E+K
Sbjct: 964 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
Query: 823 --------KQEEE--------EKKKREEEERERERERREAELRAQQEE----ETRKQQEL 862
K E++ E++K+ + ER + + E +L+ QE E KQQ
Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083
Query: 863 EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ-RMKE-QQELSLTEASLQKLQ 920
E L+K KE E++ L+ + E++Q I +L+K+I++LQ R++E ++E+ AS K +
Sbjct: 1084 EKLKK--KEFEISN-LQSKIEDEQALGI-QLQKKIKELQARIEELEEEIEAERASRAKAE 1139
Query: 921 ERRDQELRRLEE 932
++R R LEE
Sbjct: 1140 KQRSDLSRELEE 1151
Score = 44.3 bits (103), Expect = 0.001
Identities = 45/193 (23%), Positives = 84/193 (43%), Gaps = 17/193 (8%)
Query: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855
+K+LR + R R+L + + +E E EK++ +E+ +++E E + + + E+
Sbjct: 1047 EKKLRMDL-ERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105
Query: 856 TRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA- 914
Q + + + + EL E+E ++ ++ + EK+ DL R E+ L EA
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRA-----KAEKQRSDLSRELEEISERLEEAG 1160
Query: 915 -------SLQKLQERRDQELRRLEEEAC---RAAQEFLESLNFDEIDECVRNIERSLSVG 964
+ K +E Q++RR EEA A L + D + E I+ V
Sbjct: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220
Query: 965 SEFSSELAESACE 977
+ E +E E
Sbjct: 1221 QKLEKEKSEMKME 1233
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 10/125 (8%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
E R +E + + E E+K+ E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881
Query: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ-ERRDQELR 928
K + E +++ N + + +L+ E+E+ ++ + E+ + KL+ + R+ +
Sbjct: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEE-----AEERADIAESQVNKLRVKSREVHTK 1936
Query: 929 RLEEE 933
+ EE
Sbjct: 1937 VISEE 1941
Score = 40.4 bits (93), Expect = 0.018
Identities = 39/171 (22%), Positives = 81/171 (47%), Gaps = 17/171 (9%)
Query: 787 HLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERER--ERERR 844
+L+K + QL ++ +Q L + + Q E + R+ +E+E + R
Sbjct: 1250 NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSR 1309
Query: 845 EAELRAQQEEETRKQQELE---------ALQKSQKEAELTRELEKQKENKQVEEILRLEK 895
+ QQ EE ++Q E E ALQ S+ + +L RE ++++ + E L K
Sbjct: 1310 GKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSK 1369
Query: 896 EIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLN 946
++ + + + E + + ++L+E + + +RL+ AA+E +E++N
Sbjct: 1370 ANTEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQ-----AAEEHVEAVN 1414
Score = 37.7 bits (86), Expect = 0.12
Identities = 37/179 (20%), Positives = 84/179 (46%), Gaps = 22/179 (12%)
Query: 782 RRRFLHLKKAAIV-FQKQLRGQIARRV--YRQLLAEKREQEEKKKQE-------EEEKKK 831
R + LH + +++ +K+L I++ +L E R EEK K+ EE KK
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 832 REEEERERERERREAE-------LRAQQEEETR---KQQELEALQKSQKEAELTRELEKQ 881
++ ER ++ E LR + E+ +++++ L+ +E E E E++
Sbjct: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
Query: 882 KENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQE 940
+ + V+ + + E+ +++L E+ ++ LQ L ++ +++ + +A A ++
Sbjct: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILR--LQDLVDKLQAKVKSYKRQAEEAEEQ 1894
Score = 36.6 bits (83), Expect = 0.26
Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 21/175 (12%)
Query: 805 RRVYRQLLAEKREQEEK-----KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQ 859
+RV ++L EK E + + E K K E+ R E + +EL++++EE+ R
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 860 QELEALQ-KSQKEA-ELTRELE------------KQKENKQVEEILR-LEKEIEDLQRMK 904
+L A + + Q E+ E +R+L+ KQ +Q+EE+ R LE+EI+ +
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 905 EQQELSLTEASLQKLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIE 958
+ S + L + Q +QE + L+ +A E + E D R E
Sbjct: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE 1391
Score = 36.6 bits (83), Expect = 0.26
Identities = 37/147 (25%), Positives = 74/147 (50%), Gaps = 18/147 (12%)
Query: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELTRELEKQK 882
+KK+R + E +++ E AEL A Q+E EL ++ + +E+ + L+++
Sbjct: 1449 DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKREN 1508
Query: 883 ENKQ------VEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQ---ERRDQELRRLE 931
+N Q E+I K I +L+++K+Q QE +A+L++ + E + ++ R++
Sbjct: 1509 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQ 1568
Query: 932 EEACRAAQEFLESL--NFDEIDECVRN 956
E + E + +EID+ RN
Sbjct: 1569 LELNQVKSEVDRKIAEKDEEIDQLKRN 1595
Score = 33.1 bits (74), Expect = 2.9
Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 11/117 (9%)
Query: 812 LAEKREQEEKKKQEEEE-KKKREEEERERERERREAELRAQQEEE--TRKQQELEALQK- 867
L E+ + K+ E E+ KK+ E+E+ E + EAE + EE R Q EL ++
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
Query: 868 -SQKEAELTRELEKQKENK-QVEEILR--LEKEI---EDLQRMKEQQELSLTEASLQ 917
+K AE E+++ K N ++ E ++ L+ EI D R+K++ E L E +Q
Sbjct: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1634
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 491 bits (1265), Expect = e-138
Identities = 330/1058 (31%), Positives = 562/1058 (53%), Gaps = 59/1058 (5%)
Query: 5 FTEGTRVWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEE 63
F T V++ E + F T+ S G V +T+ G T K +V M+P +
Sbjct: 32 FDAKTSVFVAEPKESFVKGTIQSREGGKVTVKTEGGATLTVKDD-----QVFPMNPPKYD 86
Query: 64 GVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSR 123
++DMA +T LH +++YNL +RY IYTY G +VNPY+ + +Y+P + Y
Sbjct: 87 KIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLP-VYKPEVVTAYRG 145
Query: 124 RHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVIS----Q 179
+ E PPHIF+I++ Y+ + +NQ ILI+GESGAGKT +TK ++++ + I+ +
Sbjct: 146 KKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEK 205
Query: 180 QSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGR 239
+ E++ + +E I+ ++P++EAFGNAKTV N+NSSRFGKF++++ G +
Sbjct: 206 KKEEITSGKIQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASAD 265
Query: 240 IVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-PENYHYLNQSGCVEDK 298
I YLLEK+RVV Q ER+YHIFY + + + E E ++T P +Y +++Q G +
Sbjct: 266 IETYLLEKSRVVFQLKAERSYHIFYQITSNKKPELIEMLLITTNPYDYPFVSQ-GEISVA 324
Query: 299 TISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTAL 355
+I DQE +A+D++ F+ EE + +L ++H GN++F A+
Sbjct: 325 SIDDQEELMATDSAIDILGFTNEEKVSIYKLTGAVMHYGNLKFKQKQREEQAEPDGTEVA 384
Query: 356 GRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIK 415
++A L L+ L AL + + E + V+Q ++ +LA A+Y F W++
Sbjct: 385 DKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVEQVSNAVGALAKAVYEKMFLWMVA 444
Query: 416 KINSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEY 474
+IN ++ + + IG+LDI GFE F+ N EQ IN+ NEKLQ++FN H+F LEQ EY
Sbjct: 445 RINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEY 504
Query: 475 SREGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNH 532
+EG+ W ID+ +D C++LIEK +G+ +++ EE FP+ATD++ KL+ QH +
Sbjct: 505 KKEGIEWTFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSA 564
Query: 533 FYVKPRV----AVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF 588
+ KP+V A +F + HYAG V Y++ G LEKN+D + ++ L ++S + LF
Sbjct: 565 NFQKPKVVKGKAEAHFALIHYAGVVDYNITGWLEKNKDPLNETVVGLYQKSAMKTLAQLF 624
Query: 589 EHVSSRNNQDT---LKCGSKHRR---PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQ 642
+ + K G K + TVS+ F+++L+ LM L S++P FVRCI PN
Sbjct: 625 SGAQTAEGEGAGGGAKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNET 684
Query: 643 KMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----D 698
K P + +VL+QLR +G+LE +RI + G+ R + DF +RYKVL + A+PE D
Sbjct: 685 KTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNAS-AIPEGQFID 743
Query: 699 VRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA 758
+ LL D +++++ G TKVF + L LE+ R+++++ +A GFLA
Sbjct: 744 SKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRGFLA 803
Query: 759 RKQYRKVL---YCVVIIQKNYRAFL------LRRRFLHLKKAAIVFQKQLRGQIARRVYR 809
R +Y++++ + IQ N R+F+ + F +K + + + ++
Sbjct: 804 RVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEFQ 863
Query: 810 QLLAEKREQEEKKKQEEE-------EKKKREEEERERERERREAELRAQQEEETRKQQEL 862
++ E + E K+K+ EE EK + + + +AE R Q +T+ Q E
Sbjct: 864 KIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQLEA 923
Query: 863 ---EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ--RMKEQQELSLTEASLQ 917
E ++++ E E+ EL K+ K +E L+K+I+DL+ K ++E TE ++
Sbjct: 924 KIKEVTERAEDEEEINAEL-TAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVK 982
Query: 918 KLQERR---DQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAES 974
L E D+ + +L +E + ++L+ + +E N + E + E
Sbjct: 983 NLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEG 1042
Query: 975 ACEEKPNFNFSQPYPEEEVDEGFEADDDAFKDSPNPSE 1012
+ E++ + +++ + ++ D N +
Sbjct: 1043 SLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQ 1080
Score = 48.1 bits (113), Expect = 9e-05
Identities = 63/252 (25%), Positives = 121/252 (48%), Gaps = 32/252 (12%)
Query: 709 LYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKV 765
L DA QL KTK+ L +++ E+ +EE +A + + L +K +
Sbjct: 904 LADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDL 963
Query: 766 LYCVVIIQKNYRAFLLRRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEKK 822
+ ++K A + + L + A + + + + + ++Q L + + +E+K
Sbjct: 964 ELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKV 1023
Query: 823 --------KQEEE--------EKKKREEEERERERERREAELRAQQEE----ETRKQQEL 862
K E++ E++K+ + ER + + E +L+ QE E KQQ
Sbjct: 1024 NTLTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLD 1083
Query: 863 EALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ-RMKE-QQELSLTEASLQKLQ 920
E L+K KE E++ L+ + E++Q I +L+K+I++LQ R++E ++E+ AS K +
Sbjct: 1084 EKLKK--KEFEISN-LQSKIEDEQALGI-QLQKKIKELQARIEELEEEIEAERASRAKAE 1139
Query: 921 ERRDQELRRLEE 932
++R R LEE
Sbjct: 1140 KQRSDLSRELEE 1151
Score = 44.3 bits (103), Expect = 0.001
Identities = 45/193 (23%), Positives = 84/193 (43%), Gaps = 17/193 (8%)
Query: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855
+K+LR + R R+L + + +E E EK++ +E+ +++E E + + + E+
Sbjct: 1047 EKKLRMDL-ERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQA 1105
Query: 856 TRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEA- 914
Q + + + + EL E+E ++ ++ + EK+ DL R E+ L EA
Sbjct: 1106 LGIQLQKKIKELQARIEELEEEIEAERASRA-----KAEKQRSDLSRELEEISERLEEAG 1160
Query: 915 -------SLQKLQERRDQELRRLEEEAC---RAAQEFLESLNFDEIDECVRNIERSLSVG 964
+ K +E Q++RR EEA A L + D + E I+ V
Sbjct: 1161 GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVK 1220
Query: 965 SEFSSELAESACE 977
+ E +E E
Sbjct: 1221 QKLEKEKSEMKME 1233
Score = 42.7 bits (99), Expect = 0.004
Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 10/125 (8%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
E R +E + + E E+K+ E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 1822 EARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKV 1881
Query: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ-ERRDQELR 928
K + E +++ N + + +L+ E+E+ ++ + E+ + KL+ + R+ +
Sbjct: 1882 KSYKRQAEEAEEQSNTNLAKFRKLQHELEE-----AEERADIAESQVNKLRVKSREVHTK 1936
Query: 929 RLEEE 933
+ EE
Sbjct: 1937 VISEE 1941
Score = 40.4 bits (93), Expect = 0.018
Identities = 39/171 (22%), Positives = 81/171 (47%), Gaps = 17/171 (9%)
Query: 787 HLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERER--ERERR 844
+L+K + QL ++ +Q L + + Q E + R+ +E+E + R
Sbjct: 1250 NLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSR 1309
Query: 845 EAELRAQQEEETRKQQELE---------ALQKSQKEAELTRELEKQKENKQVEEILRLEK 895
+ QQ EE ++Q E E ALQ S+ + +L RE ++++ + E L K
Sbjct: 1310 GKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSK 1369
Query: 896 EIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLN 946
++ + + + E + + ++L+E + + +RL+ AA+E +E++N
Sbjct: 1370 ANTEVAQWRTKYETDAIQRT-EELEEAKKKLAQRLQ-----AAEEHVEAVN 1414
Score = 37.7 bits (86), Expect = 0.12
Identities = 37/179 (20%), Positives = 84/179 (46%), Gaps = 22/179 (12%)
Query: 782 RRRFLHLKKAAIV-FQKQLRGQIARRV--YRQLLAEKREQEEKKKQE-------EEEKKK 831
R + LH + +++ +K+L I++ +L E R EEK K+ EE KK
Sbjct: 1718 RVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKK 1777
Query: 832 REEEERERERERREAE-------LRAQQEEETR---KQQELEALQKSQKEAELTRELEKQ 881
++ ER ++ E LR + E+ +++++ L+ +E E E E++
Sbjct: 1778 EQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQK 1837
Query: 882 KENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQE 940
+ + V+ + + E+ +++L E+ ++ LQ L ++ +++ + +A A ++
Sbjct: 1838 RNAEAVKGLRKHERRVKELTYQTEEDRKNILR--LQDLVDKLQAKVKSYKRQAEEAEEQ 1894
Score = 36.6 bits (83), Expect = 0.26
Identities = 46/175 (26%), Positives = 80/175 (45%), Gaps = 21/175 (12%)
Query: 805 RRVYRQLLAEKREQEEK-----KKQEEEEKKKREEEERERERERREAELRAQQEEETRKQ 859
+RV ++L EK E + + E K K E+ R E + +EL++++EE+ R
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 860 QELEALQ-KSQKEA-ELTRELE------------KQKENKQVEEILR-LEKEIEDLQRMK 904
+L A + + Q E+ E +R+L+ KQ +Q+EE+ R LE+EI+ +
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAKNALA 1336
Query: 905 EQQELSLTEASLQKLQERRDQELR-RLEEEACRAAQEFLESLNFDEIDECVRNIE 958
+ S + L + Q +QE + L+ +A E + E D R E
Sbjct: 1337 HALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEE 1391
Score = 36.6 bits (83), Expect = 0.26
Identities = 37/147 (25%), Positives = 74/147 (50%), Gaps = 18/147 (12%)
Query: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEA-ELTRELEKQK 882
+KK+R + E +++ E AEL A Q+E EL ++ + +E+ + L+++
Sbjct: 1449 DKKQRNFDKILAEWKQKCEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKREN 1508
Query: 883 ENKQ------VEEILRLEKEIEDLQRMKEQ--QELSLTEASLQKLQ---ERRDQELRRLE 931
+N Q E+I K I +L+++K+Q QE +A+L++ + E + ++ R++
Sbjct: 1509 KNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQ 1568
Query: 932 EEACRAAQEFLESL--NFDEIDECVRN 956
E + E + +EID+ RN
Sbjct: 1569 LELNQVKSEVDRKIAEKDEEIDQLKRN 1595
Score = 33.1 bits (74), Expect = 2.9
Identities = 36/117 (30%), Positives = 60/117 (51%), Gaps = 11/117 (9%)
Query: 812 LAEKREQEEKKKQEEEE-KKKREEEERERERERREAELRAQQEEE--TRKQQELEALQK- 867
L E+ + K+ E E+ KK+ E+E+ E + EAE + EE R Q EL ++
Sbjct: 1518 LTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSE 1577
Query: 868 -SQKEAELTRELEKQKENK-QVEEILR--LEKEI---EDLQRMKEQQELSLTEASLQ 917
+K AE E+++ K N ++ E ++ L+ EI D R+K++ E L E +Q
Sbjct: 1578 VDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQ 1634
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 489 bits (1260), Expect = e-138
Identities = 319/959 (33%), Positives = 526/959 (54%), Gaps = 50/959 (5%)
Query: 11 VWLRENGQHF-PSTVNSCAEGIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDMA 69
V++ ++ Q F + + S G V T+YG+ T K+ + Q +P + ++DMA
Sbjct: 37 VFVPDDKQEFVKAKIVSREGGKVTAETEYGKTVTVKEDQVMQQ-----NPPKFDKIEDMA 91
Query: 70 SLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGEL 129
LT LH +++YNL RY IYTY G +VNPY+ + +Y P + Y + E
Sbjct: 92 MLTFLHEPAVLYNLKDRYGSWMIYTYSGLFCVTVNPYKWLP-VYTPEVVAAYRGKKRSEA 150
Query: 130 PPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLELSLKEK 189
PPHIF+I++ Y+ + +NQ ILI+GESGAGKT +TK ++++ +VI+ + S K++
Sbjct: 151 PPHIFSISDNAYQYMLTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIG-DRSKKDQ 209
Query: 190 T---SCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLE 246
+ +E I++++P +EAFGNAKTV N+NSSRFGKF++++ G + I YLLE
Sbjct: 210 SPGKGTLEDQIIQANPALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLE 269
Query: 247 KNRVVRQNPGERNYHIFYALLAGLEHEEREEFYL-STPENYHYLNQSGCVEDKTISDQES 305
K+RV+ Q ER+YHIFY +L+ + E + + + P +Y +++Q G +I D E
Sbjct: 270 KSRVIFQLKAERDYHIFYQILSNKKPELLDMLLITNNPYDYAFISQ-GETTVASIDDAEE 328
Query: 306 FREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELL 362
A DV+ F+ EE + +L I+H GN++F A+ +SA L+
Sbjct: 329 LMATDNAFDVLGFTSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEEADKSAYLM 388
Query: 363 GLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIK 422
GL+ L L + + E + NVQQ + + +LA A+Y F W++ +IN+ ++
Sbjct: 389 GLNSADLLKGLCHPRVKVGNEYVTKGQNVQQVIYATGALAKAVYERMFNWMVTRINATLE 448
Query: 423 GNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVW 481
+ + IG+LDI GFE F+ N FEQ IN+ NEKLQ++FN H+F LEQ EY +EG+ W
Sbjct: 449 TKQPRQYFIGVLDIAGFEIFDFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 508
Query: 482 EDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQH-ANNHFYVKPRV 539
ID+ +D C+DLIEK +G+++++ EE FP+ATD T KL H + + KPR
Sbjct: 509 TFIDFGMDLQACIDLIEKPMGIMSILEEECMFPKATDMTFKAKLFDNHLGKSANFQKPRN 568
Query: 540 AVN----NFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSS-- 593
+F + HYAG V Y++ G L+KN+D + ++ L ++S + LF + +
Sbjct: 569 IKGKPEAHFSLIHYAGIVDYNIIGWLQKNKDPLNETVVGLYQKSSLKLLSTLFANYAGAD 628
Query: 594 ---RNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQ 650
+ K GS + TVS+ +++L+ LM L S++P FVRCI PN K P D
Sbjct: 629 APIEKGKGKAKKGSSFQ--TVSALHRENLNKLMTNLRSTHPHFVRCIIPNETKSPGVMDN 686
Query: 651 AVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPE----DVRGKCTSL 706
+V++QLR +G+LE +RI + G+ R + DF +RY++L A+PE D R L
Sbjct: 687 PLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRIL-NPAAIPEGQFIDSRKGAEKL 745
Query: 707 LQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVL 766
L D +++++ G TKVF + L LE+ R+E +S I+A G LAR +Y+K+L
Sbjct: 746 LSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIITRIQAQSRGVLARMEYKKLL 805
Query: 767 Y---CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKK 823
+++IQ N RAF+ + + + K + L+ + + E +E +
Sbjct: 806 ERRDSLLVIQWNIRAFMGVKNWPWM-KLYFKIKPLLKSAEREKEMASMKEEFTRLKEALE 864
Query: 824 QEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE 883
+ E +K+ EE+ +E+ + +L+ Q E++ E Q + + +L ++++ E
Sbjct: 865 KSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNE 924
Query: 884 NKQVEEIL---------RLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEE 933
+ EE + +LE E +L+R + +L LT A ++K + + +++ L EE
Sbjct: 925 RLEDEEEMNAELTAKKRKLEDECSELKR--DIDDLELTLAKVEKEKHATENKVKNLTEE 981
Score = 48.5 bits (114), Expect = 7e-05
Identities = 58/247 (23%), Positives = 103/247 (41%), Gaps = 26/247 (10%)
Query: 773 QKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKR 832
Q++ +R L + + Q + + ++ R L ++ E+ K+Q EEE K +
Sbjct: 1267 QRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAK 1326
Query: 833 EEEERERERERREAE-LRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEI 890
+ R + + LR Q EEET + EL+ L K+ E R + ++ EE+
Sbjct: 1327 NALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEEL 1386
Query: 891 LRLEKEIEDLQRMKEQQE----LSLTEASLQKLQERRDQELRRL----EEEACRAAQEFL 942
+K++ QR++E +E ++ +SL+K + R E+ L E AA
Sbjct: 1387 EEAKKKL--AQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDK 1444
Query: 943 ESLNFDEI--------DECVRNIERSLSVGSEFSSEL------AESACEEKPNFNFSQPY 988
+ NFD+I +E +E S S+EL E + E F
Sbjct: 1445 KQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKN 1504
Query: 989 PEEEVDE 995
+EE+ +
Sbjct: 1505 LQEEISD 1511
Score = 46.6 bits (109), Expect = 3e-04
Identities = 46/178 (25%), Positives = 85/178 (47%), Gaps = 20/178 (11%)
Query: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855
+K++R + R R+L + + +E E +K++ +E ++++ E R + E+
Sbjct: 1041 EKKVRMDL-ERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Query: 856 TRKQQELEALQKSQKE-----AELTRELEKQKENKQVEEILR--LEKEIEDL-QRMKEQQ 907
Q LQK KE EL ELE ++ + E LR L +E+E++ +R++E
Sbjct: 1100 LGSQ-----LQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAG 1154
Query: 908 ELSLTEASLQKLQE------RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIER 959
+ + + K +E RRD E L+ EA AA + + E+ E + N++R
Sbjct: 1155 GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQR 1212
Score = 46.2 bits (108), Expect = 3e-04
Identities = 72/310 (23%), Positives = 136/310 (43%), Gaps = 39/310 (12%)
Query: 680 QDFYKRYKVLMRNLALPEDVRGKCTSLLQ---------------LYDASNSEWQLGKTKV 724
++F + + L ++ A +++ K SLLQ L DA QL K K+
Sbjct: 854 EEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCDQLIKNKI 913
Query: 725 FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRR 784
L +++ E+ +EE +A + + L + R + + + K +
Sbjct: 914 QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKE------ 967
Query: 785 FLHLKKAAIVFQKQLRGQIAR--RVYRQLLAEKREQEEKKKQ-----EEEEKKKREEEER 837
K A K L ++A + +L EK+ +E +Q + EE K +
Sbjct: 968 ----KHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLTKA 1023
Query: 838 ERERERREAELRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRLEKE 896
+ + E++ +L E+E + + +LE A +K + + +LT+E EN + + RL+K+
Sbjct: 1024 KVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKK 1083
Query: 897 IEDLQ----RMKEQQEL-SLTEASLQKLQERRDQELRRLE-EEACRAAQEFLESLNFDEI 950
+L R++++Q L S + L++LQ R ++ LE E RA E L S E+
Sbjct: 1084 DFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSREL 1143
Query: 951 DECVRNIERS 960
+E +E +
Sbjct: 1144 EEISERLEEA 1153
Score = 42.0 bits (97), Expect = 0.006
Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 10/125 (8%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
E R +E + + E E+K+ E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 1816 EARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKV 1875
Query: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQER-RDQELR 928
K + E +++ N + + +++ E+++ ++ + E+ + KL+ + RD +
Sbjct: 1876 KAYKRQAEEAEEQANTNLSKFRKVQHELDE-----AEERADIAESQVNKLRAKSRDIGTK 1930
Query: 929 RLEEE 933
L EE
Sbjct: 1931 GLNEE 1935
Score = 40.4 bits (93), Expect = 0.018
Identities = 51/222 (22%), Positives = 95/222 (42%), Gaps = 30/222 (13%)
Query: 813 AEKREQEEKKKQEEEEKKKREEEERERERERREA-----------------ELRAQQEEE 855
AE+ ++ + K + E E R+ + +EA +L+ Q EEE
Sbjct: 1263 AEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEE 1322
Query: 856 TRKQQEL-EALQKSQKEAELTRE-LEKQKENK-QVEEIL-RLEKEIEDLQRMKEQQELSL 911
+ + L ALQ ++ + +L RE E++ E K +++ +L + E+ + E +
Sbjct: 1323 VKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR 1382
Query: 912 TEASLQKLQERRDQELRRLEE--EACRAAQEFLESLNF---DEIDECVRNIERSLSVGSE 966
TE L++ +++ Q L+ EE EA A LE +EI++ + ++ERS + +
Sbjct: 1383 TE-ELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAA 1441
Query: 967 FSSE---LAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFK 1005
+ + E K + SQ E E + FK
Sbjct: 1442 LDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1483
Score = 39.3 bits (90), Expect = 0.040
Identities = 52/273 (19%), Positives = 124/273 (45%), Gaps = 40/273 (14%)
Query: 727 RESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFL 786
++ L+++L+K+ E + A + LG +K+ +++ + +++ A
Sbjct: 1073 KQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEA-------- 1124
Query: 787 HLKKAAIVFQKQLRGQIARRVYRQLLAEKREQE----------EKKKQEEEEKKKREEEE 836
++ A ++LR ++R + + ++E+ E+ KK++ E +K +R+ EE
Sbjct: 1125 --ERTARAKVEKLRSDLSREL--EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1180
Query: 837 RERERERREAELRAQQEEETRK--------QQELEALQKSQKEAEL-----TRELEK-QK 882
+ E A LR + + + Q+ + L+K + E +L T +E+ K
Sbjct: 1181 ATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK 1240
Query: 883 ENKQVEEILR-LEKEIEDLQRMKEQQELSLTEASLQ--KLQERRDQELRRLEEEACRAAQ 939
+E++ R LE ++ + + E+ + S+ + + Q KLQ + R+L+E+ +Q
Sbjct: 1241 AKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQ 1300
Query: 940 EFLESLNF-DEIDECVRNIERSLSVGSEFSSEL 971
L + ++++ R +E + + + L
Sbjct: 1301 LTRGKLTYTQQLEDLKRQLEEEVKAKNALAHAL 1333
Score = 37.7 bits (86), Expect = 0.12
Identities = 45/182 (24%), Positives = 81/182 (44%), Gaps = 25/182 (13%)
Query: 816 REQEEKKKQEEEEKKKREEEERERERERREA--------ELRAQQEEETRKQQELEALQK 867
++Q K E K+K EE + E E ++EA +L+ EE + + K
Sbjct: 1444 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1503
Query: 868 SQKE--AELTREL--------EKQKENKQVE-EILRLEKEIEDLQRMKEQQELSLTEASL 916
+ +E ++LT +L E +K KQ+E E + L+ +E+ + E +E + A L
Sbjct: 1504 NLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQL 1563
Query: 917 QKLQERRDQELRRLE-----EEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSEL 971
+ Q + + E + E E+A R ++SL +D R+ +L V + +L
Sbjct: 1564 EFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQ-TSLDAETRSRNEALRVKKKMEGDL 1622
Query: 972 AE 973
E
Sbjct: 1623 NE 1624
Score = 36.6 bits (83), Expect = 0.26
Identities = 46/210 (21%), Positives = 92/210 (43%), Gaps = 41/210 (19%)
Query: 824 QEEEEKKKREEEERE-RERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQK 882
Q E + K EE +R + + A+L+ + E +R+ E EAL +LT + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 883 ENKQVEEILR--------LEKEIEDLQRMKEQ-QELSLTEASLQKLQERRDQE------- 926
+Q+EE ++ L+ D ++EQ +E + +A LQ++ + + E
Sbjct: 1315 LKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1374
Query: 927 -----LRRLEE---------EACRAAQEFLESLN-----FDEIDECVRNIERSLSVGSEF 967
++R EE + + A+E +E++N ++ ++N L V E
Sbjct: 1375 YETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVER 1434
Query: 968 SSELAESACEEKPNFN-----FSQPYPEEE 992
S+ A + +++ NF+ + Q Y E +
Sbjct: 1435 SNAAAAALDKKQRNFDKILAEWKQKYEESQ 1464
Score = 36.6 bits (83), Expect = 0.26
Identities = 53/230 (23%), Positives = 108/230 (46%), Gaps = 25/230 (10%)
Query: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEET 856
++LR + + + LAE+ E ++ + + ++++ + ++L+ + EE
Sbjct: 1686 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAV 1745
Query: 857 R--KQQELEALQKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQ-RMKEQQELSL 911
+ + E +A + A + EL+K+++ E ++ +E+ I+DLQ R+ E ++++L
Sbjct: 1746 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAL 1805
Query: 912 T--EASLQKLQERRDQELRRLEEEACRAAQEF---------LESLNFDEIDECVRNIER- 959
+ LQKL+ R + LE E R A+ ++ L + + +E +N+ R
Sbjct: 1806 KGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTY-QTEEDRKNLLRL 1864
Query: 960 -----SLSVGSEFSSELAESACEEKPNFNFSQ-PYPEEEVDEGFEADDDA 1003
L + + AE A EE+ N N S+ + E+DE E D A
Sbjct: 1865 QDLVDKLQLKVKAYKRQAEEA-EEQANTNLSKFRKVQHELDEAEERADIA 1913
Score = 35.0 bits (79), Expect = 0.76
Identities = 60/250 (24%), Positives = 105/250 (42%), Gaps = 35/250 (14%)
Query: 806 RVYRQLLAEKRE-----QEEKKKQEEEEKK----KREEEERERERERREAELRAQQEEET 856
+V +QL AEK E +E + E EE K + E + + E ER+ AE + E+
Sbjct: 1528 KVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1587
Query: 857 RK--------QQELEALQKSQKEA-ELTRELEKQKENKQVE------EILRLEKEIEDLQ 901
R Q L+A +S+ EA + +++E +++ +K+++ LQ
Sbjct: 1588 RNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1647
Query: 902 RMKEQQELSLTEA--SLQKLQE-----RRDQELRRLEEEACRAAQEFLESLNFDEIDECV 954
+ + ++ L +A + L+E R L + E E RA E E E +
Sbjct: 1648 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELI 1707
Query: 955 RNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDDAFK---DSPNPS 1011
ER + S+ ++ L + + + Q EE V E A++ A K D+ +
Sbjct: 1708 ETSERVQLLHSQ-NTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMA 1766
Query: 1012 EHGHSDQRTS 1021
E +Q TS
Sbjct: 1767 EELKKEQDTS 1776
>gi|194328685 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 486 bits (1251), Expect = e-136
Identities = 308/842 (36%), Positives = 468/842 (55%), Gaps = 60/842 (7%)
Query: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQ 120
N GV DM L L+ + + NL +R+ ++IYTYIGS++ SVNPY+ + +Y P +E+
Sbjct: 13 NMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLP-IYSPEKVEE 71
Query: 121 YSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ 180
Y R+ EL PHIFA+++E YR L + +QCILI+GESGAGKTE++KL++ +++ + +
Sbjct: 72 YRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGK 131
Query: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240
E++ V+ +L+S+P++EAFGNAKTV N+NSSRFGK++ + KG+ GG I
Sbjct: 132 GAEVNQ------VKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVI 185
Query: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTP-ENYHYLNQSGCVEDKT 299
+YLLEK+RVV+Q GERN+H+FY LL+G E + L Y+YL+ +
Sbjct: 186 SNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDS-AKVNG 244
Query: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAG------GAQVSFKT 353
+ D +FR V AM ++ F E V ++A +L LGNIEF +++ K
Sbjct: 245 VDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKN 304
Query: 354 ALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWV 413
L EL G+D + L A + R++ + E++ T LNV QA +RD+LA LY+ F W+
Sbjct: 305 ELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWL 364
Query: 414 IKKINSRIKGNEDF--KSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQ 471
+ +IN IK K +G+LDI+GFE FE N FEQF INY NEKLQ+ F + EQ
Sbjct: 365 VNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQ 424
Query: 472 LEYSREGLVWEDIDWIDNGECLDLIEKKL-GLLALINEESHFP-QATDSTLLEKLHSQHA 529
EY RE + W ID+ +N DLIE G+LA+++EE P TD T LEKL +Q
Sbjct: 425 EEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKL-NQVC 483
Query: 530 NNHFYVKPRVA-----VNN-------FGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLR 577
H + + R++ +N+ F ++HYAG+V Y V G ++KN D DL +
Sbjct: 484 ATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMW 543
Query: 578 ESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCI 637
++ I LF + K K R PT SQFK S+ +LM L + NP ++RCI
Sbjct: 544 KASHALIKSLFP------EGNPAKINLK-RPPTAGSQFKASVATLMKNLQTKNPNYIRCI 596
Query: 638 KPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL--AL 695
KPN +K F++A+V +Q+RY G+LE VR+R+AGYA R+ ++ +RYK+L +
Sbjct: 597 KPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHW 656
Query: 696 PEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQ-KLEKRREEEVSHAAMVIRAHVL 754
R L + E+ G++K+F+R KLE R++ + A +I+
Sbjct: 657 KGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYR 716
Query: 755 GFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAE 814
G+ R + + ++I YR + ++R+ K +A+V Q +RG AR++ R+L +
Sbjct: 717 GWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQ 776
Query: 815 KREQEE--------KKKQEEEEKKKREEEERERER----------ERREAELRAQQEEET 856
KR +E Q E ++ +EE R + + EL+ +EE
Sbjct: 777 KRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEAR 836
Query: 857 RK 858
RK
Sbjct: 837 RK 838
>gi|240120050 myosin IB isoform 1 [Homo sapiens]
Length = 1136
Score = 486 bits (1251), Expect = e-136
Identities = 308/842 (36%), Positives = 468/842 (55%), Gaps = 60/842 (7%)
Query: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQ 120
N GV DM L L+ + + NL +R+ ++IYTYIGS++ SVNPY+ + +Y P +E+
Sbjct: 13 NMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLP-IYSPEKVEE 71
Query: 121 YSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ 180
Y R+ EL PHIFA+++E YR L + +QCILI+GESGAGKTE++KL++ +++ + +
Sbjct: 72 YRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGK 131
Query: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240
E++ V+ +L+S+P++EAFGNAKTV N+NSSRFGK++ + KG+ GG I
Sbjct: 132 GAEVNQ------VKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVI 185
Query: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTP-ENYHYLNQSGCVEDKT 299
+YLLEK+RVV+Q GERN+H+FY LL+G E + L Y+YL+ +
Sbjct: 186 SNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDS-AKVNG 244
Query: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAG------GAQVSFKT 353
+ D +FR V AM ++ F E V ++A +L LGNIEF +++ K
Sbjct: 245 VDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKN 304
Query: 354 ALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWV 413
L EL G+D + L A + R++ + E++ T LNV QA +RD+LA LY+ F W+
Sbjct: 305 ELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWL 364
Query: 414 IKKINSRIKGNEDF--KSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQ 471
+ +IN IK K +G+LDI+GFE FE N FEQF INY NEKLQ+ F + EQ
Sbjct: 365 VNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQ 424
Query: 472 LEYSREGLVWEDIDWIDNGECLDLIEKKL-GLLALINEESHFP-QATDSTLLEKLHSQHA 529
EY RE + W ID+ +N DLIE G+LA+++EE P TD T LEKL +Q
Sbjct: 425 EEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKL-NQVC 483
Query: 530 NNHFYVKPRVA-----VNN-------FGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLR 577
H + + R++ +N+ F ++HYAG+V Y V G ++KN D DL +
Sbjct: 484 ATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMW 543
Query: 578 ESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCI 637
++ I LF + K K R PT SQFK S+ +LM L + NP ++RCI
Sbjct: 544 KASHALIKSLFP------EGNPAKINLK-RPPTAGSQFKASVATLMKNLQTKNPNYIRCI 596
Query: 638 KPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL--AL 695
KPN +K F++A+V +Q+RY G+LE VR+R+AGYA R+ ++ +RYK+L +
Sbjct: 597 KPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHW 656
Query: 696 PEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQ-KLEKRREEEVSHAAMVIRAHVL 754
R L + E+ G++K+F+R KLE R++ + A +I+
Sbjct: 657 KGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYR 716
Query: 755 GFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAE 814
G+ R + + ++I YR + ++R+ K +A+V Q +RG AR++ R+L +
Sbjct: 717 GWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQ 776
Query: 815 KREQEE--------KKKQEEEEKKKREEEERERER----------ERREAELRAQQEEET 856
KR +E Q E ++ +EE R + + EL+ +EE
Sbjct: 777 KRCKEAVTTIAAYWHGTQARRELRRLKEEARNKHAIAVIWAYWLGSKARRELKRLKEEAR 836
Query: 857 RK 858
RK
Sbjct: 837 RK 838
>gi|44889481 myosin IB isoform 2 [Homo sapiens]
Length = 1078
Score = 483 bits (1244), Expect = e-136
Identities = 297/785 (37%), Positives = 450/785 (57%), Gaps = 42/785 (5%)
Query: 61 NEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQ 120
N GV DM L L+ + + NL +R+ ++IYTYIGS++ SVNPY+ + +Y P +E+
Sbjct: 13 NMIGVGDMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLP-IYSPEKVEE 71
Query: 121 YSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQ 180
Y R+ EL PHIFA+++E YR L + +QCILI+GESGAGKTE++KL++ +++ + +
Sbjct: 72 YRNRNFYELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGK 131
Query: 181 SLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRI 240
E++ V+ +L+S+P++EAFGNAKTV N+NSSRFGK++ + KG+ GG I
Sbjct: 132 GAEVNQ------VKEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVI 185
Query: 241 VDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTP-ENYHYLNQSGCVEDKT 299
+YLLEK+RVV+Q GERN+H+FY LL+G E + L Y+YL+ +
Sbjct: 186 SNYLLEKSRVVKQPRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDS-AKVNG 244
Query: 300 ISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITAG------GAQVSFKT 353
+ D +FR V AM ++ F E V ++A +L LGNIEF +++ K
Sbjct: 245 VDDAANFRTVRNAMQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDESKIKDKN 304
Query: 354 ALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWV 413
L EL G+D + L A + R++ + E++ T LNV QA +RD+LA LY+ F W+
Sbjct: 305 ELKEICELTGIDQSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWL 364
Query: 414 IKKINSRIKGNEDF--KSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQ 471
+ +IN IK K +G+LDI+GFE FE N FEQF INY NEKLQ+ F + EQ
Sbjct: 365 VNRINESIKAQTKVRKKVMGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQ 424
Query: 472 LEYSREGLVWEDIDWIDNGECLDLIEKKL-GLLALINEESHFP-QATDSTLLEKLHSQHA 529
EY RE + W ID+ +N DLIE G+LA+++EE P TD T LEKL +Q
Sbjct: 425 EEYIREDIEWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKL-NQVC 483
Query: 530 NNHFYVKPRVA-----VNN-------FGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLR 577
H + + R++ +N+ F ++HYAG+V Y V G ++KN D DL +
Sbjct: 484 ATHQHFESRMSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMW 543
Query: 578 ESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCI 637
++ I LF + K K R PT SQFK S+ +LM L + NP ++RCI
Sbjct: 544 KASHALIKSLFP------EGNPAKINLK-RPPTAGSQFKASVATLMKNLQTKNPNYIRCI 596
Query: 638 KPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL--AL 695
KPN +K F++A+V +Q+RY G+LE VR+R+AGYA R+ ++ +RYK+L +
Sbjct: 597 KPNDKKAAHIFNEALVCHQIRYLGLLENVRVRRAGYAFRQAYEPCLERYKMLCKQTWPHW 656
Query: 696 PEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQ-KLEKRREEEVSHAAMVIRAHVL 754
R L + E+ G++K+F+R KLE R++ + A +I+
Sbjct: 657 KGPARSGVEVLFNELEIPVEEYSFGRSKIFIRNPRTLFKLEDLRKQRLEDLATLIQKIYR 716
Query: 755 GFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAE 814
G+ R + + ++I YR + ++R+ K +A+V Q +RG AR++ R+L +
Sbjct: 717 GWKCRTHFLLMKKSQIVIAAWYRRYAQQKRYQQTKSSALVIQSYIRGWKARKILRELKHQ 776
Query: 815 KREQE 819
KR +E
Sbjct: 777 KRCKE 781
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 483 bits (1244), Expect = e-136
Identities = 310/925 (33%), Positives = 518/925 (56%), Gaps = 49/925 (5%)
Query: 48 TITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQ 107
T+ + +V M+P + ++DMA +T LH +++YNL +RY IYTY G +VNPY+
Sbjct: 71 TLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYK 130
Query: 108 PIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTEST 167
+ +Y+P + Y + E PPHIF+I++ Y+ + DNQ ILI+GESGAGKT +T
Sbjct: 131 WLP-VYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGKTVNT 189
Query: 168 KLILKFLSVIS---QQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224
K ++++ + I+ + E + +E I++++P++EAFGNAKTV N+NSSRFGKF
Sbjct: 190 KRVIQYFATIAVTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSSRFGKF 249
Query: 225 VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLST-P 283
++++ G + I YLLEK+RV Q ER+YHIFY +++ + E + +ST P
Sbjct: 250 IRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMSNKKPELIDLLLISTNP 309
Query: 284 ENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF-- 341
++ +++Q G V +I D E A+D++ FS EE + +L ++H GN++F
Sbjct: 310 FDFPFVSQ-GEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMHYGNMKFKQ 368
Query: 342 -ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDS 400
A+ ++ L+GL+ ++ L + + E + NVQQ +S +
Sbjct: 369 KQREEQAEPDGTEVADKAGYLMGLNSAEMLKGLCCPRVKVGNEYVTKGQNVQQVTNSVGA 428
Query: 401 LAMALYACCFEWVIKKINSRIKGNEDFK-SIGILDIFGFENFEVNHFEQFNINYANEKLQ 459
LA A+Y F W++ +IN ++ + + IG+LDI GFE F+ N EQ IN+ NEKLQ
Sbjct: 429 LAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQ 488
Query: 460 EYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDS 518
++FN H+F LEQ EY +EG+ WE ID+ +D C++LIEK +G+ +++ EE FP+ATD+
Sbjct: 489 QFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDT 548
Query: 519 TLLEKLHSQH---ANNHFYVKPR--VAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLL 573
+ KL+ QH +NN KP A +F + HYAG V Y++ G L+KN+D + ++
Sbjct: 549 SFKNKLYDQHLGKSNNFQKPKPAKGKAEAHFSLVHYAGTVDYNIAGWLDKNKDPLNETVV 608
Query: 574 NLLRESRFDFIYDLFEHVSSRNNQDT--LKCGSKHRR---PTVSSQFKDSLHSLMATLSS 628
L ++S + LF + + D+ K G K + TVS+ F+++L+ LM L S
Sbjct: 609 GLYQKSSLKLLSFLFSNYAGAETGDSGGSKKGGKKKGSSFQTVSAVFRENLNKLMTNLRS 668
Query: 629 SNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKV 688
++P FVRC+ PN K P D +V++QLR +G+LE +RI + G+ R + DF +RY++
Sbjct: 669 THPHFVRCLIPNETKTPGVMDHYLVMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRI 728
Query: 689 LMRNLALPE----DVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSH 744
L + A+PE D + LL D +++ G TKVF + L LE+ R+E++
Sbjct: 729 LNAS-AIPEGQFIDSKNASEKLLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVT 787
Query: 745 AAMVIRAHVLGFLARKQYRKVLY---CVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG 801
+A G+L R +++K++ + IQ N R+F+ H + F +++
Sbjct: 788 LMTSTQAVCRGYLMRVEFKKMMERRDSIFCIQYNIRSFM---NVKHWPWMNLFF--KIKP 842
Query: 802 QIARRVYRQLLAEKREQEEKKKQE----EEEKKKREEEERERERERREAELRAQQEEET- 856
+ + +A +E E+ K+E E +K+ EE+ +E+ + +L+ Q E E
Sbjct: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902
Query: 857 -RKQQELEALQKSQ-----KEAELTRELEKQKE--NKQVEEILRLEKEIEDLQRMKEQQE 908
++ E L KS+ K ELT LE+++E ++ V + LE + L+R + E
Sbjct: 903 MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLE 962
Query: 909 LSLTEASLQKLQERRDQELRRLEEE 933
L+LT+ ++K + + +++ L EE
Sbjct: 963 LTLTK--VEKEKHATENKVKNLSEE 985
Score = 52.4 bits (124), Expect = 5e-06
Identities = 53/192 (27%), Positives = 95/192 (49%), Gaps = 24/192 (12%)
Query: 796 QKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE 855
+K+LR + R R+L + + +E E +K++ EE+ +++E E ++L+A+ ++E
Sbjct: 1045 EKKLRADL-ERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFEL--SQLQAKIDDE 1101
Query: 856 TRKQQELEALQKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQRMKEQQELSLTE 913
++ +LQ +K EL +E+ +E + E LR +EK+ DL R E+ L E
Sbjct: 1102 -----QVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEE 1156
Query: 914 AS--------LQKLQE------RRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIER 959
AS + K +E RRD E L+ EA A ++ + E+ E + N++R
Sbjct: 1157 ASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQR 1216
Query: 960 SLSVGSEFSSEL 971
+ SEL
Sbjct: 1217 VKQKLEKEKSEL 1228
Score = 47.4 bits (111), Expect = 1e-04
Identities = 56/214 (26%), Positives = 102/214 (47%), Gaps = 33/214 (15%)
Query: 786 LHLKKAAIVFQKQLRGQIARRVYRQ--LLAEKREQEEKKKQEEEE-KKKREEEERER--- 839
L+++KA + Q G+++ RV + L+++ + ++ Q+ EE K++ EEE + +
Sbjct: 1277 LNMQKARLQTQN---GELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAM 1333
Query: 840 ----ERERREAE-LRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRL 893
+ R + + LR Q EEE + EL+ AL K+ E R + ++ EE+
Sbjct: 1334 AHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1393
Query: 894 EKEIEDLQRMKEQQELSLTE----ASLQKLQERRDQE----LRRLEEEACRAAQEFLESL 945
+K++ QR++E +E + T ASL+K ++R E +R LE A +
Sbjct: 1394 KKKL--AQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQR 1451
Query: 946 NFDEI--------DECVRNIERSLSVGSEFSSEL 971
NFD++ DE +E + S+EL
Sbjct: 1452 NFDKVLAEWKQKLDESQAELEAAQKESRSLSTEL 1485
Score = 47.0 bits (110), Expect = 2e-04
Identities = 43/162 (26%), Positives = 83/162 (51%), Gaps = 7/162 (4%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAE 873
E ++E + E K + EE + E E + QEE + +++ K+ +EAE
Sbjct: 1472 EAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531
Query: 874 LTREL-EKQKENKQVE-EILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLE 931
T++L E++K + QV E + E E+ + ++ Q ELS ++ L + +D+E+ +L+
Sbjct: 1532 KTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLK 1591
Query: 932 EEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAE 973
+ RAA E L+S+ +D +R+ +L + + +L E
Sbjct: 1592 RNSQRAA-EALQSV----LDAEIRSRNDALRLKKKMEGDLNE 1628
Score = 43.9 bits (102), Expect = 0.002
Identities = 47/207 (22%), Positives = 100/207 (48%), Gaps = 32/207 (15%)
Query: 810 QLLAEKREQEEKKKQEEEE---------KKKREEEERERERERREAELRAQQEEETRKQQ 860
+L+A+KR E+K + + K ++E+ E + + E+ A +E ++ +
Sbjct: 939 ELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTK 998
Query: 861 ELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQ 920
E ++LQ++ ++ ++E+ K N ++ +LE++ +DL+ EQ+ +KL+
Sbjct: 999 EKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQE---------KKLR 1049
Query: 921 ERRDQELRRLEEEACRAAQEFLESLNFD--EIDECVRNIERSLSVGSEFSSELAESACEE 978
++ R+LE + + +QE + L D +I+E ++ E E S A+ E+
Sbjct: 1050 ADLERAKRKLEGD-LKMSQESIMDLENDKQQIEEKLKKKE------FELSQLQAKIDDEQ 1102
Query: 979 KPNFNFSQPYPE-----EEVDEGFEAD 1000
+ F + E EE++E EA+
Sbjct: 1103 VHSLQFQKKIKELQARIEELEEEIEAE 1129
Score = 39.3 bits (90), Expect = 0.040
Identities = 30/124 (24%), Positives = 61/124 (49%), Gaps = 10/124 (8%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
E R +E + + + E+K+ E + + ER+ E+ Q EE+ R Q ++ LQ
Sbjct: 1820 ENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKV 1879
Query: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQER-RDQELR 928
K + E +++ N Q+ R++ E+E+ + + E+ + KL+ + RD +
Sbjct: 1880 KSYKRQAEEAEEQANTQLSRCRRVQHELEE-----AAERADIAESQVNKLRAKSRDVGSQ 1934
Query: 929 RLEE 932
++EE
Sbjct: 1935 KMEE 1938
Score = 36.6 bits (83), Expect = 0.26
Identities = 33/151 (21%), Positives = 76/151 (50%), Gaps = 18/151 (11%)
Query: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKE-AELTRELEKQK 882
+KK+R + E +++ + +AEL A Q+E EL ++ + +E + L ++
Sbjct: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN 1506
Query: 883 ENKQ------VEEILRLEKEIEDLQRMKE--QQELSLTEASLQKLQ---ERRDQELRRLE 931
+N Q E+I K +++ ++ K+ +QE S + +L++++ E + ++ R++
Sbjct: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQ 1566
Query: 932 EEACRAAQEFLESL--NFDEIDECVRNIERS 960
E + E + +EI++ RN +R+
Sbjct: 1567 LELSQVKSELDRKVIEKDEEIEQLKRNSQRA 1597
Score = 32.0 bits (71), Expect = 6.4
Identities = 42/162 (25%), Positives = 72/162 (44%), Gaps = 42/162 (25%)
Query: 782 RRRFLHLKKAAIV-FQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERE 840
R + LH + +++ +K+L IA Q AE E ++ + EEK K+ +
Sbjct: 1716 RVQLLHSQNTSLINTKKKLEADIA-----QCQAEV-ENSIQESRNAEEKAKKAITD---- 1765
Query: 841 RERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDL 900
A EE +K+Q+ A LE+ K+N LE+ ++DL
Sbjct: 1766 --------AAMMAEELKKEQDTSA------------HLERMKKN--------LEQTVKDL 1797
Query: 901 Q-RMKEQQELSLT--EASLQKLQERRDQELRRLEEEACRAAQ 939
Q R+ E ++L+L + +QKL+ R + L+ E R A+
Sbjct: 1798 QHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAE 1839
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 483 bits (1243), Expect = e-136
Identities = 300/788 (38%), Positives = 447/788 (56%), Gaps = 57/788 (7%)
Query: 55 TAMHPTNEEGVDDMASLTELHG-GSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLY 113
+A+ + GV D L + + NL +R++ N IYTYIG +L SVNPY+ + +Y
Sbjct: 19 SALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQ-IY 77
Query: 114 EPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKF 173
ME+Y E+PPH+FA+A+ YR L +Q ++ISGESGAGKTE+TK +L+F
Sbjct: 78 SRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQF 137
Query: 174 LSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKG 233
+ E+ V +L+S+P++EAFGNAKT+ N+NSSRFGK++ + KG
Sbjct: 138 YAETCPAP------ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKG 191
Query: 234 NIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS-TPENYHYLNQS 292
GG I+ YLLEK+RVV QN GERN+HIFY LL G E E L P++Y YL +
Sbjct: 192 APVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKG 251
Query: 293 GCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFIT--AGGAQVS 350
C + +I+D+ ++ V A+ V+ F+++EV ++ ++A +LHLGNI F AQV+
Sbjct: 252 QCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVT 311
Query: 351 FKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCF 410
+ L LL ++ + L +ALT R + +GEE+L+PLN++QA +RD+LA A+Y+ F
Sbjct: 312 TENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTF 371
Query: 411 EWVIKKINSRIKGNEDFKS--------IGILDIFGFENFEVNHFEQFNINYANEKLQEYF 462
W++ KIN R ++D +S +G+LDI+GFE F+ N FEQF INY NEKLQ+ F
Sbjct: 372 TWLVGKIN-RSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLF 430
Query: 463 NKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKL-GLLALINEESHFP-QATDSTL 520
+ EQ EY EG+ WE + + +N DL+E+K G++++++EE P +ATD T
Sbjct: 431 IELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTF 490
Query: 521 LEKL-----HSQHANNHFYVKPR----VAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDD 571
LEKL H H H R + F + HYAGEV Y V G L+KN D +
Sbjct: 491 LEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRN 550
Query: 572 LLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNP 631
L + S+ + F D + K R TV++QFK SL L+ L S P
Sbjct: 551 LKETMCSSKNPIMSQCF---------DRSELSDKKRPETVATQFKMSLLQLVEILQSKEP 601
Query: 632 FFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMR 691
+VRCIKPN K P +FD+ ++ +Q++Y G+LE +R+R+AG+A RR ++ F +RYK L
Sbjct: 602 AYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCP 661
Query: 692 N-----LALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLR-----ESLEQKLEKRREEE 741
P+D L++ E+++G+TK+F+R + E LE RR+
Sbjct: 662 ETWPTWAGRPQD---GVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQS- 717
Query: 742 VSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG 801
A I+A GF R+++ +V + IQ +R L RR+ K AA ++ +RG
Sbjct: 718 ---LATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRG 774
Query: 802 QIARRVYR 809
+ R R
Sbjct: 775 FVLRHAPR 782
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 483 bits (1243), Expect = e-136
Identities = 300/788 (38%), Positives = 447/788 (56%), Gaps = 57/788 (7%)
Query: 55 TAMHPTNEEGVDDMASLTELHG-GSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLY 113
+A+ + GV D L + + NL +R++ N IYTYIG +L SVNPY+ + +Y
Sbjct: 38 SALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQ-IY 96
Query: 114 EPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKF 173
ME+Y E+PPH+FA+A+ YR L +Q ++ISGESGAGKTE+TK +L+F
Sbjct: 97 SRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQF 156
Query: 174 LSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKG 233
+ E+ V +L+S+P++EAFGNAKT+ N+NSSRFGK++ + KG
Sbjct: 157 YAETCPAP------ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKG 210
Query: 234 NIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS-TPENYHYLNQS 292
GG I+ YLLEK+RVV QN GERN+HIFY LL G E E L P++Y YL +
Sbjct: 211 APVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKG 270
Query: 293 GCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFIT--AGGAQVS 350
C + +I+D+ ++ V A+ V+ F+++EV ++ ++A +LHLGNI F AQV+
Sbjct: 271 QCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVT 330
Query: 351 FKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCF 410
+ L LL ++ + L +ALT R + +GEE+L+PLN++QA +RD+LA A+Y+ F
Sbjct: 331 TENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTF 390
Query: 411 EWVIKKINSRIKGNEDFKS--------IGILDIFGFENFEVNHFEQFNINYANEKLQEYF 462
W++ KIN R ++D +S +G+LDI+GFE F+ N FEQF INY NEKLQ+ F
Sbjct: 391 TWLVGKIN-RSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLF 449
Query: 463 NKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKL-GLLALINEESHFP-QATDSTL 520
+ EQ EY EG+ WE + + +N DL+E+K G++++++EE P +ATD T
Sbjct: 450 IELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTF 509
Query: 521 LEKL-----HSQHANNHFYVKPR----VAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDD 571
LEKL H H H R + F + HYAGEV Y V G L+KN D +
Sbjct: 510 LEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRN 569
Query: 572 LLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNP 631
L + S+ + F D + K R TV++QFK SL L+ L S P
Sbjct: 570 LKETMCSSKNPIMSQCF---------DRSELSDKKRPETVATQFKMSLLQLVEILQSKEP 620
Query: 632 FFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMR 691
+VRCIKPN K P +FD+ ++ +Q++Y G+LE +R+R+AG+A RR ++ F +RYK L
Sbjct: 621 AYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCP 680
Query: 692 N-----LALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLR-----ESLEQKLEKRREEE 741
P+D L++ E+++G+TK+F+R + E LE RR+
Sbjct: 681 ETWPTWAGRPQD---GVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQS- 736
Query: 742 VSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG 801
A I+A GF R+++ +V + IQ +R L RR+ K AA ++ +RG
Sbjct: 737 ---LATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRG 793
Query: 802 QIARRVYR 809
+ R R
Sbjct: 794 FVLRHAPR 801
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 483 bits (1243), Expect = e-136
Identities = 300/788 (38%), Positives = 447/788 (56%), Gaps = 57/788 (7%)
Query: 55 TAMHPTNEEGVDDMASLTELHG-GSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLY 113
+A+ + GV D L + + NL +R++ N IYTYIG +L SVNPY+ + +Y
Sbjct: 3 SALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQ-IY 61
Query: 114 EPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKF 173
ME+Y E+PPH+FA+A+ YR L +Q ++ISGESGAGKTE+TK +L+F
Sbjct: 62 SRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQF 121
Query: 174 LSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKG 233
+ E+ V +L+S+P++EAFGNAKT+ N+NSSRFGK++ + KG
Sbjct: 122 YAETCPAP------ERGGAVRDRLLQSNPVLEAFGNAKTLRNDNSSRFGKYMDVQFDFKG 175
Query: 234 NIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS-TPENYHYLNQS 292
GG I+ YLLEK+RVV QN GERN+HIFY LL G E E L P++Y YL +
Sbjct: 176 APVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLRRLGLERNPQSYLYLVKG 235
Query: 293 GCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFIT--AGGAQVS 350
C + +I+D+ ++ V A+ V+ F+++EV ++ ++A +LHLGNI F AQV+
Sbjct: 236 QCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVT 295
Query: 351 FKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCF 410
+ L LL ++ + L +ALT R + +GEE+L+PLN++QA +RD+LA A+Y+ F
Sbjct: 296 TENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTF 355
Query: 411 EWVIKKINSRIKGNEDFKS--------IGILDIFGFENFEVNHFEQFNINYANEKLQEYF 462
W++ KIN R ++D +S +G+LDI+GFE F+ N FEQF INY NEKLQ+ F
Sbjct: 356 TWLVGKIN-RSLASKDVESPSWRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLF 414
Query: 463 NKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKKL-GLLALINEESHFP-QATDSTL 520
+ EQ EY EG+ WE + + +N DL+E+K G++++++EE P +ATD T
Sbjct: 415 IELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKGIISILDEECLRPGEATDLTF 474
Query: 521 LEKL-----HSQHANNHFYVKPR----VAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDD 571
LEKL H H H R + F + HYAGEV Y V G L+KN D +
Sbjct: 475 LEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRN 534
Query: 572 LLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNP 631
L + S+ + F D + K R TV++QFK SL L+ L S P
Sbjct: 535 LKETMCSSKNPIMSQCF---------DRSELSDKKRPETVATQFKMSLLQLVEILQSKEP 585
Query: 632 FFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMR 691
+VRCIKPN K P +FD+ ++ +Q++Y G+LE +R+R+AG+A RR ++ F +RYK L
Sbjct: 586 AYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRYKSLCP 645
Query: 692 N-----LALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLR-----ESLEQKLEKRREEE 741
P+D L++ E+++G+TK+F+R + E LE RR+
Sbjct: 646 ETWPTWAGRPQD---GVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDALEVRRQS- 701
Query: 742 VSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRG 801
A I+A GF R+++ +V + IQ +R L RR+ K AA ++ +RG
Sbjct: 702 ---LATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRG 758
Query: 802 QIARRVYR 809
+ R R
Sbjct: 759 FVLRHAPR 766
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 483 bits (1243), Expect = e-136
Identities = 326/1027 (31%), Positives = 550/1027 (53%), Gaps = 57/1027 (5%)
Query: 30 GIVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKR 89
G V+ T+ G+ T K+ + Q +P + ++DMA LT LH ++++NL +RY
Sbjct: 57 GKVIAETENGKTVTVKEDQVLQQ-----NPPKFDKIEDMAMLTFLHEPAVLFNLKERYAA 111
Query: 90 NQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHD 149
IYTY G +VNPY+ + +Y + Y + E PPHIF+I++ Y+ + +
Sbjct: 112 WMIYTYSGLFCVTVNPYKWLP-VYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYMLTDRE 170
Query: 150 NQCILISGESGAGKTESTKLILKF---LSVISQQSLELSLKEKTSCVERAILESSPIMEA 206
NQ ILI+GESGAGKT +TK ++++ ++ I + + + +E I++++P +EA
Sbjct: 171 NQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQANPALEA 230
Query: 207 FGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYAL 266
FGNAKTV N+NSSRFGKF++++ G + I YLLEK+RV+ Q ERNYHIFY +
Sbjct: 231 FGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYHIFYQI 290
Query: 267 LAGLEHEEREEFYL-STPENYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVRE 325
L+ + E + + + P +Y +++Q G V +I D E +A DV+ F+ EE
Sbjct: 291 LSNKKPELLDMLLVTNNPYDYAFVSQ-GEVSVASIDDSEELMATDSAFDVLGFTSEEKAG 349
Query: 326 VSRLLAGILHLGNIEF---ITAGGAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRG 382
V +L I+H GN++F A+ +SA L+GL+ L L + +
Sbjct: 350 VYKLTGAIMHYGNMKFKQKQREEQAEPDGTEDADKSAYLMGLNSADLLKGLCHPRVKVGN 409
Query: 383 EEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKINSRIKGNEDFK-SIGILDIFGFENF 441
E + +VQQ S +LA A+Y F W++ +IN+ ++ + + IG+LDI GFE F
Sbjct: 410 EYVTKGQSVQQVYYSIGALAKAVYEKMFNWMVTRINATLETKQPRQYFIGVLDIAGFEIF 469
Query: 442 EVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDW-IDNGECLDLIEKKL 500
+ N FEQ IN+ NEKLQ++FN H+F LEQ EY +EG+ W ID+ +D C+DLIEK +
Sbjct: 470 DFNSFEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLQACIDLIEKPM 529
Query: 501 GLLALINEESHFPQATDSTLLEKLHSQH-ANNHFYVKPRVAVN----NFGVKHYAGEVQY 555
G+++++ EE FP+ATD T KL+ H ++ + KPR +F + HYAG V Y
Sbjct: 530 GIMSILEEECMFPKATDMTFKAKLYDNHLGKSNNFQKPRNIKGKQEAHFSLIHYAGTVDY 589
Query: 556 DVRGILEKNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRR----PTV 611
++ G LEKN+D + ++ L ++S + LF ++ + D+ K ++ TV
Sbjct: 590 NILGWLEKNKDPLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGSSFQTV 649
Query: 612 SSQFKDSLHSLMATLSSSNPFFVRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKA 671
S+ +++L+ LM L +++P FVRCI PN +K P D +V++QLR +G+LE +RI +
Sbjct: 650 SALHRENLNKLMTNLRTTHPHFVRCIIPNERKAPGVMDNPLVMHQLRCNGVLEGIRICRK 709
Query: 672 GYAVRRPFQDFYKRYKVLMRNLALPE----DVRGKCTSLLQLYDASNSEWQLGKTKVFLR 727
G+ R + DF +RY++L +A+PE D R LL D +++++ G TKVF +
Sbjct: 710 GFPNRILYGDFRQRYRIL-NPVAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFK 768
Query: 728 ESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLY---CVVIIQKNYRAFL---- 780
L LE+ R+E +S ++A G L R +++K++ +++IQ N RAF+
Sbjct: 769 AGLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKN 828
Query: 781 -----LRRRFLHLKKAA-----IVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKK 830
L + L K+A + K+ G+I + + A ++E EEK +EK
Sbjct: 829 WPWMKLYFKIKPLLKSAETEKEMATMKEEFGRI-KETLEKSEARRKELEEKMVSLLQEKN 887
Query: 831 KREEEERERERERREAELRAQQEEETRKQQELEALQKSQK---EAELTRELEKQKENKQV 887
+ + + + +AE R Q + + Q E + + +++ E E+ EL K+ K
Sbjct: 888 DLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAEL-TAKKRKLE 946
Query: 888 EEILRLEKEIEDLQ--RMKEQQELSLTEASLQKLQERR---DQELRRLEEEACRAAQEFL 942
+E L+K+I+DL+ K ++E TE ++ L E D+ + +L +E +
Sbjct: 947 DECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQ 1006
Query: 943 ESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFEADDD 1002
++L+ +++E N V E + E + E++ + +++ + +
Sbjct: 1007 QALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQE 1066
Query: 1003 AFKDSPN 1009
+ D N
Sbjct: 1067 SIMDLEN 1073
Score = 53.1 bits (126), Expect = 3e-06
Identities = 68/303 (22%), Positives = 126/303 (41%), Gaps = 37/303 (12%)
Query: 728 ESLEQKLEKRREE-------EVSHAAMVIRAHV----LGFLARKQYRKVLYCVVIIQKNY 776
+ ++QKLEK + E S+ +I+A + Q + + Q++
Sbjct: 1213 QRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL 1272
Query: 777 RAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEE 836
F +R L + + Q + + + ++ R L+ ++ E+ K+Q EEE K +
Sbjct: 1273 NDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALA 1332
Query: 837 RERERERREAE-LRAQQEEETRKQQELE-ALQKSQKEAELTRELEKQKENKQVEEILRLE 894
+ R + + LR Q EEET + EL+ L K+ E R + ++ EE+ +
Sbjct: 1333 HALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAK 1392
Query: 895 KEIEDLQRMKEQQE----LSLTEASLQKLQERRDQELRRL----EEEACRAAQEFLESLN 946
K++ QR+++ +E ++ +SL+K + R E+ L E AA + N
Sbjct: 1393 KKL--AQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRN 1450
Query: 947 FDEI--------DECVRNIERSLSVGSEFSSEL------AESACEEKPNFNFSQPYPEEE 992
FD+I +E +E S S+EL E + E F +EE
Sbjct: 1451 FDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEE 1510
Query: 993 VDE 995
+ +
Sbjct: 1511 ISD 1513
Score = 45.8 bits (107), Expect = 4e-04
Identities = 49/193 (25%), Positives = 85/193 (44%), Gaps = 21/193 (10%)
Query: 788 LKKAAIVFQKQ---LRGQIA--RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERE 842
L K+ + ++Q L G + ++V L KR+ E K +E E ++ + E +
Sbjct: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEK 1081
Query: 843 RREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDL 900
++ E Q+ + +++ ALQ +K E +E+ +E + E R +EK DL
Sbjct: 1082 LKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDL 1141
Query: 901 QRMKEQQELSLTEA--------SLQKLQE------RRDQELRRLEEEACRAAQEFLESLN 946
R E+ L EA + K +E RRD E L+ EA AA + +
Sbjct: 1142 SRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADS 1201
Query: 947 FDEIDECVRNIER 959
E+ E + N++R
Sbjct: 1202 VAELGEQIDNLQR 1214
Score = 42.7 bits (99), Expect = 0.004
Identities = 72/362 (19%), Positives = 145/362 (40%), Gaps = 68/362 (18%)
Query: 730 LEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLK 789
LE+KL+K+ + + + VL +K+ +++N L +
Sbjct: 1078 LEEKLKKKEFDINQQNSKIEDEQVLALQLQKK----------LKENQARIEELEEELEAE 1127
Query: 790 KAAIVFQKQLRGQIARRVYRQLLAEKREQE----------EKKKQEEEEKKKREEEERER 839
+ A ++LR ++R + + ++E+ E+ KK++ E +K +R+ EE
Sbjct: 1128 RTARAKVEKLRSDLSREL--EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1185
Query: 840 ERERREAELRAQQEEETRK--------QQELEALQKSQKEAELTRELEKQKENKQVEEIL 891
+ E A LR + + + Q+ + L+K + E +L EL+ N +E+I+
Sbjct: 1186 QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL--ELDDVTSN--MEQII 1241
Query: 892 RLEKEIEDLQRMKEQQ-----------ELSLTEASLQ--KLQERRDQELRRLEEEACRAA 938
+ + +E + R E Q + SL + + Q KLQ + R+LEE+ +
Sbjct: 1242 KAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALIS 1301
Query: 939 QEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVDEGFE 998
Q L++ + E +++R L + + LA + + + + + EEE + E
Sbjct: 1302 QLTRGKLSYTQQME---DLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1358
Query: 999 ADDDAFKDSPNPSEHGHSDQRTSGIRTSDDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQ 1058
QR S+ + Y D + T ++ LA +Q
Sbjct: 1359 L------------------QRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ 1400
Query: 1059 DS 1060
D+
Sbjct: 1401 DA 1402
Score = 38.5 bits (88), Expect = 0.068
Identities = 27/113 (23%), Positives = 56/113 (49%), Gaps = 9/113 (7%)
Query: 814 EKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEE----TRKQQELEALQKSQ 869
E R +E + + E E+K+ E + R+ ERR EL Q EE+ R Q ++ LQ
Sbjct: 1818 EARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKV 1877
Query: 870 KEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQER 922
K + E +++ N + + +++ E+++ ++ + E+ + KL+ +
Sbjct: 1878 KAYKRQAEEAEEQANTNLSKFRKVQHELDE-----AEERADIAESQVNKLRAK 1925
Score = 37.4 bits (85), Expect = 0.15
Identities = 54/230 (23%), Positives = 108/230 (46%), Gaps = 25/230 (10%)
Query: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEET 856
++LR + + + LAE+ E ++ + + ++++ E +L+++ EE
Sbjct: 1688 EELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAV 1747
Query: 857 R--KQQELEALQKSQKEAELTRELEKQKENKQVEEILR--LEKEIEDLQ-RMKEQQELSL 911
+ + E +A + A + EL+K+++ E ++ +E+ I+DLQ R+ E ++++L
Sbjct: 1748 QECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIAL 1807
Query: 912 T--EASLQKLQERRDQELRRLEEEACRAAQEF---------LESLNFDEIDECVRNIER- 959
+ LQKL+ R + LE E R A+ ++ L + + +E +N+ R
Sbjct: 1808 KGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTY-QTEEDKKNLLRL 1866
Query: 960 -----SLSVGSEFSSELAESACEEKPNFNFSQ-PYPEEEVDEGFEADDDA 1003
L + + AE A EE+ N N S+ + E+DE E D A
Sbjct: 1867 QDLVDKLQLKVKAYKRQAEEA-EEQANTNLSKFRKVQHELDEAEERADIA 1915
Score = 37.0 bits (84), Expect = 0.20
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 13/125 (10%)
Query: 828 EKKKREEE----ERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKE 883
+KK+R + E +++ E ++EL + Q+E EL L+ + +E+ E K++
Sbjct: 1445 DKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKREN 1504
Query: 884 NKQVEEILRLE-------KEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACR 936
EEI L K + +L+++++Q E+ E LQ E + L E + R
Sbjct: 1505 KNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLE--LQSALEEAEASLEHEEGKILR 1562
Query: 937 AAQEF 941
A EF
Sbjct: 1563 AQLEF 1567
Score = 36.2 bits (82), Expect = 0.34
Identities = 45/186 (24%), Positives = 81/186 (43%), Gaps = 33/186 (17%)
Query: 816 REQEEKKKQEEEEKKKREEEERERERERREA--------ELRAQQEEETRKQQELEALQK 867
++Q K E K+K EE + E E ++EA +L+ EE + + K
Sbjct: 1446 KKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENK 1505
Query: 868 SQKE--AELTRELEKQKENKQVEEILRLEKEIE--DLQRMKEQQELSL------------ 911
+ +E ++LT +L + +N E +R + E+E +LQ E+ E SL
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565
Query: 912 ----TEASLQKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEF 967
+A +++ +D+E+ E+A R Q ++SL +D R+ L V +
Sbjct: 1566 EFNQIKAEIERKLAEKDEEM----EQAKRNHQRVVDSLQ-TSLDAETRSRNEVLRVKKKM 1620
Query: 968 SSELAE 973
+L E
Sbjct: 1621 EGDLNE 1626
Score = 35.0 bits (79), Expect = 0.76
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 16/184 (8%)
Query: 806 RVYRQLLAEKRE-----QEEKKKQEEEEKK----KREEEERERERERREAELRAQQEEET 856
+V +QL EK E +E + E EE K + E + + E ER+ AE + E+
Sbjct: 1530 KVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAK 1589
Query: 857 RKQQELEALQKSQKEAELTRELEKQKENKQVE-EILRLEKEIEDLQRM--KEQQELSLTE 913
R Q + ++ +AE E + K++E ++ +E ++ RM + Q+++ +
Sbjct: 1590 RNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1649
Query: 914 ASLQKLQERRDQELRR----LEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSS 969
+ L+ Q + D +R E A + L +E+ V ERS + +
Sbjct: 1650 SLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELI 1709
Query: 970 ELAE 973
E +E
Sbjct: 1710 ETSE 1713
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 483 bits (1243), Expect = e-136
Identities = 325/983 (33%), Positives = 528/983 (53%), Gaps = 66/983 (6%)
Query: 10 RVWLR-ENGQHFPSTVNSCAEG-IVVFRTDYGQVFTYKQSTITHQKVTAMHPTNEEGVDD 67
RVW+ E + + V S A G V T +V +++ ++ M+P + ++D
Sbjct: 76 RVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKVLMVREA-----ELQPMNPPRFDLLED 130
Query: 68 MASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRRHLG 127
MA +T L+ S+++NL QRY R IYTY G ++NPY+ + +Y + + Y +
Sbjct: 131 MAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLP-VYTASVVAAYKGKRRS 189
Query: 128 ELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQ------QS 181
+ PPHI+A+A+ Y + + DNQ +LI+GESGAGKT +TK ++++ ++++ +
Sbjct: 190 DSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKK 249
Query: 182 LELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIV 241
+ + +E I+E++P MEAFGNAKT+ N+NSSRFGKF++++ G + I
Sbjct: 250 AQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADID 309
Query: 242 DYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS-TPENYHYLNQSGCVEDKTI 300
YLLEK+RV+ Q PGER+YH++Y +L+G + E ++ LS P +YH+ +Q G + +
Sbjct: 310 SYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQ-GVITVDNM 368
Query: 301 SDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEF---ITAGGAQVSFKTALGR 357
+D E AMD++ FS +E +++ +LH GN++F A+ + +
Sbjct: 369 NDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADK 428
Query: 358 SAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACCFEWVIKKI 417
+A L+G+ L L + + E + +V+Q V + +LA A Y F W++ +I
Sbjct: 429 AAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRI 488
Query: 418 NSRI--KGNEDFKSIGILDIFGFENFEVNHFEQFNINYANEKLQEYFNKHIFSLEQLEYS 475
N + K F IG+LDI GFE FE N FEQ IN+ NEKLQ++FN+H+F LEQ EY
Sbjct: 489 NQTLDTKLPRQF-FIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYK 547
Query: 476 REGLVWEDIDW-IDNGECLDLIEKKLGLLALINEESHFPQATDSTLLEKLHSQHANN--H 532
REG+ W ID+ +D C+DLIEK LG+L+++ EE FP+A+D++ KL+ HA +
Sbjct: 548 REGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDNHAGKSPN 607
Query: 533 FYV----KPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDLLNLLRESRFDFIYDLF 588
F K R +F V HYAG V Y + G LEKN+D + ++ + ++S+ + L+
Sbjct: 608 FQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLY 667
Query: 589 EHVSSRNNQDTLKCGSKHRR------PTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQ 642
E+ + + + K G K +R TVS K++L+ LM L ++ P FVRCI PN
Sbjct: 668 ENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNEN 727
Query: 643 KMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNLALPEDV--- 699
K P D +VL+QLR +G+LE +RI + G+ R + DF +RY++L + A+P+D
Sbjct: 728 KTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPS-AIPDDTFMD 786
Query: 700 -RGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA 758
R LL D ++++Q G TKVF + L LE+ R++ ++ +++A G L
Sbjct: 787 SRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLM 846
Query: 759 RKQYRKVL---YCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEK 815
R +Y+++L + IQ N RAF + + + K + LR A L AE
Sbjct: 847 RLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWM-KLFFKMKPLLRSAQAEEELAALRAEL 905
Query: 816 REQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQE-------LEALQKS 868
R E ++++ EE +E+ + L+ Q E++ E +Q
Sbjct: 906 RGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLE 965
Query: 869 QKEAELTRELEKQKE---------NKQVEEILRLEKEIEDLQ--RMKEQQELSLTEASLQ 917
K EL+ LE ++E K +E L+K+I+DL+ K ++E TE ++
Sbjct: 966 GKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVK 1025
Query: 918 KLQERRDQELRRLEEEACRAAQE 940
L E E+ L+E R +E
Sbjct: 1026 NLTE----EMAALDESVARLTKE 1044
Score = 47.4 bits (111), Expect = 1e-04
Identities = 46/224 (20%), Positives = 102/224 (45%), Gaps = 19/224 (8%)
Query: 726 LRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRF 785
LR +L KR+E E +H ++ + L + + + R LL +
Sbjct: 908 LRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDN------LADAEERCHLLIKSK 961
Query: 786 LHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEE---------KKKREEEE 836
+ L+ ++L + V L A +R+ E++ + +++ K ++E++
Sbjct: 962 VQLEGKVKELSERLEDE--EEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQA 1019
Query: 837 RERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKE 896
E + + E+ A E R +E +ALQ++ ++A + E+ + + + LRLE++
Sbjct: 1020 TENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQ 1079
Query: 897 IEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAAQE 940
+EDL+ EQ++ ++ + + + +L+ +E AAQ+
Sbjct: 1080 VEDLECSLEQEK--KLRMDTERAKRKLEGDLKLTQESVADAAQD 1121
Score = 45.1 bits (105), Expect = 7e-04
Identities = 36/125 (28%), Positives = 63/125 (50%), Gaps = 9/125 (7%)
Query: 818 QEEKKKQEEEEKKKREEEERERER------ERREAELRAQQEEETRKQQELEALQKSQKE 871
Q +KK +E + + + EEE E ER E++ AE + EE + + +E Q+E
Sbjct: 1152 QMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQRE 1211
Query: 872 AELTRELEKQKENKQVEE-ILRLEKEIEDLQRMKEQQELSLTEA--SLQKLQERRDQELR 928
RE E + +++EE LR E + L+R + + L E SLQ+++++ ++E
Sbjct: 1212 GCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKS 1271
Query: 929 RLEEE 933
L E
Sbjct: 1272 ELRME 1276
Score = 45.1 bits (105), Expect = 7e-04
Identities = 42/160 (26%), Positives = 77/160 (48%), Gaps = 30/160 (18%)
Query: 817 EQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETR----KQQELEALQKSQKE- 871
+++++ + E+++R+EEE +RE E + E R E R ++ LEAL+ ++E
Sbjct: 1492 DKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKREN 1551
Query: 872 -------AELT----------RELEKQK---ENKQVEEILRLEK-----EIEDLQRMKEQ 906
++LT +ELEK K E ++ E LE+ E+E+ + ++ Q
Sbjct: 1552 KNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQ 1611
Query: 907 QELSLTEASLQKLQERRDQELRRLEEEACRAAQEFLESLN 946
ELS +A + + +D+E L RA + SL+
Sbjct: 1612 LELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLD 1651
Score = 42.0 bits (97), Expect = 0.006
Identities = 74/298 (24%), Positives = 126/298 (42%), Gaps = 48/298 (16%)
Query: 727 RESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFL 786
++ LE+KL+K+ E + V +LG +K+ +++ RA L L
Sbjct: 1122 KQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKEL---------QARAEELEEE-L 1171
Query: 787 HLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREA 846
++AA ++ R + AR + + L+E+ E+ + E ++ E E R RRE
Sbjct: 1172 EAERAARARVEKQRAEAAREL--EELSERLEEAGGASAGQREGCRKREAELG--RLRREL 1227
Query: 847 ELRAQQEEET-----RKQQELEALQKSQKEA--ELTRELEKQKEN---------KQVEEI 890
E A + E T RKQ E A Q ++ + ++LEK+K VE +
Sbjct: 1228 EEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETL 1287
Query: 891 LRLEKEIEDLQRMKEQQ-----------ELSLTEASLQ--KLQERRDQELRRLEEEACRA 937
R + E L R E Q + L +AS Q +LQ + R LEE+ C
Sbjct: 1288 TRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLI 1347
Query: 938 AQ-EFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEKPNFNFSQPYPEEEVD 994
+Q ++L ++E R +E S+ S LA + + + + + EEE +
Sbjct: 1348 SQLSRGKALAAQSLEELRRQLEEE----SKAKSALAHAVQALRHDCDLLREQHEEEAE 1401
Score = 42.0 bits (97), Expect = 0.006
Identities = 36/126 (28%), Positives = 61/126 (48%), Gaps = 12/126 (9%)
Query: 812 LAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKE 871
L + + +EE+ ++EE++ E E+ + ERR + L A ELE L+ + ++
Sbjct: 1694 LMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAA----------ELEELRAALEQ 1743
Query: 872 AELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLE 931
E +R L +Q+ + E + L + L K++ E L A L E QE R E
Sbjct: 1744 GERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL--AQLSGEVEEAAQERREAE 1801
Query: 932 EEACRA 937
E+A +A
Sbjct: 1802 EKAKKA 1807
Score = 40.4 bits (93), Expect = 0.018
Identities = 59/265 (22%), Positives = 116/265 (43%), Gaps = 22/265 (8%)
Query: 709 LYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLA---RKQYRKV 765
L DA L K+KV L +++ E+ +EE +A + R L +K +
Sbjct: 947 LADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDL 1006
Query: 766 LYCVVIIQKNYRAFLLRRRFLHLKKAAI---VFQKQLRGQIARRVYRQLLAEKREQEEKK 822
+ +K +A + + L + AA+ V + + + ++Q L + + +E++
Sbjct: 1007 KLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRV 1066
Query: 823 KQEEEEKKKREEEER------ERERERREAELRAQQEEETRK-QQELEALQKSQKEAELT 875
+ K + E++ E+E+ +LR E RK + +L+ Q+S +A
Sbjct: 1067 SALTKAKLRLEQQVEDLECSLEQEK-----KLRMDTERAKRKLEGDLKLTQESVADAAQD 1121
Query: 876 RELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEAC 935
++ ++K K+ E+ +L +ED Q + Q + + E LQ E ++EL E A
Sbjct: 1122 KQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKE--LQARAEELEEELE--AERAA 1177
Query: 936 RAAQEFLESLNFDEIDECVRNIERS 960
RA E + E++E +E +
Sbjct: 1178 RARVEKQRAEAARELEELSERLEEA 1202
Score = 38.9 bits (89), Expect = 0.052
Identities = 45/173 (26%), Positives = 78/173 (45%), Gaps = 19/173 (10%)
Query: 810 QLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQ 869
+L E + KQ+ EEK K+++ E + LR + E+ Q + + +
Sbjct: 1109 KLTQESVADAAQDKQQLEEKLKKKDSELS------QLSLRVEDEQLLGAQMQKKIKELQA 1162
Query: 870 KEAELTRELEKQKENKQVEEILRLE--KEIEDL-QRMKE--------QQELSLTEASLQK 918
+ EL ELE ++ + E R E +E+E+L +R++E ++ EA L +
Sbjct: 1163 RAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGR 1222
Query: 919 LQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSEL 971
L RR+ E L EA AA ++ E+ E V +++R + SEL
Sbjct: 1223 L--RRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSEL 1273
Score = 38.5 bits (88), Expect = 0.068
Identities = 61/286 (21%), Positives = 109/286 (38%), Gaps = 37/286 (12%)
Query: 809 RQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELE----- 863
RQL ++ + + E + EE+E + R L AQ EE R+Q E E
Sbjct: 1317 RQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKS 1376
Query: 864 ----ALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKL 919
A+Q + + +L RE +++ Q E L K ++ + + + E + + ++L
Sbjct: 1377 ALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRT-EEL 1435
Query: 920 QERRDQELRRLEE-----EACRAAQEFLESLNF---DEIDECVRNIERSLSVGSEFSSEL 971
+E + + RL+E EA A LE E ++ +ER+ S + +
Sbjct: 1436 EEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQ 1495
Query: 972 --AESACEEKPNFNFSQPYPEEEVDEGFEA---DDDAFKDSPNPSEHGHSDQRTSGIRTS 1026
E A EE+ EEE+ EA + HGH + +
Sbjct: 1496 RHLERALEERRR-------QEEEMQRELEAAQRESRGLGTELFRLRHGHEE----ALEAL 1544
Query: 1027 DDSSEEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSSSGEST 1072
+ E+ + + + S D L S+Q+ + GE +
Sbjct: 1545 ETLKRENKNLQEEI---SDLTDQVSLSGKSIQELEKTKKALEGEKS 1587
Score = 38.5 bits (88), Expect = 0.068
Identities = 38/179 (21%), Positives = 88/179 (49%), Gaps = 34/179 (18%)
Query: 782 RRRFLHLKKAAIVFQKQ-LRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKR-------- 832
R LH + ++ QK+ L +A+ L+ + E+ ++++E EEK K+
Sbjct: 1761 RLNLLHSQNTGLLNQKKKLEADLAQ------LSGEVEEAAQERREAEEKAKKAITDAAMM 1814
Query: 833 -EEEERERER-----------ERREAELRAQQEEETRK-----QQELEALQKSQKEAELT 875
EE ++E++ E+ EL+A+ EE + +++++ L+ +E E
Sbjct: 1815 AEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAE 1874
Query: 876 RELEKQKENKQVEEILRLEKEIEDL--QRMKEQQELSLTEASLQKLQERRDQELRRLEE 932
+ E++K + ++ + + E+ +++L Q ++++ L+ + + KLQ + R+ EE
Sbjct: 1875 LDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1933
Score = 36.2 bits (82), Expect = 0.34
Identities = 47/168 (27%), Positives = 70/168 (41%), Gaps = 35/168 (20%)
Query: 797 KQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQE--- 853
K L Q + RQL E+E K K + + + RE+ E E AQ E
Sbjct: 1354 KALAAQSLEELRRQL-----EEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQR 1408
Query: 854 ---------EETRKQQELEALQKSQ--KEAELTRELEKQKENKQVEEI-----------L 891
+ R + E +A+Q+++ +EA+ L Q+ + VE L
Sbjct: 1409 LLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKL 1468
Query: 892 RLEKEIEDLQRMKEQQELSLTEASLQKLQ---ERRDQELRRLEEEACR 936
RL+ E ED+ E + + A+L K Q ER +E RR EEE R
Sbjct: 1469 RLQTESEDV--TLELERATSAAAALDKKQRHLERALEERRRQEEEMQR 1514
Score = 34.7 bits (78), Expect = 0.99
Identities = 49/198 (24%), Positives = 85/198 (42%), Gaps = 32/198 (16%)
Query: 806 RVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEAL 865
R+ +L K E + K +++EE R +R L+A + ETR + E L
Sbjct: 1609 RIQLELSQVKAEVDRKLAEKDEECANLR-----RNHQRAVESLQASLDAETRARNEALRL 1663
Query: 866 QKSQK------------------EAE-LTRELEKQKENKQV--EEILRLEKEIEDLQRMK 904
+K + EA+ TR ++ Q + +Q +E RL E+ + Q
Sbjct: 1664 KKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHE-QAQA 1722
Query: 905 EQQELSLTEASLQKLQERRDQ--ELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLS 962
++ SL A L++L+ +Q RRL E+ A E L L+ + N ++ L
Sbjct: 1723 LERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTG--LLNQKKKLE 1780
Query: 963 VG-SEFSSELAESACEEK 979
++ S E+ E+A E +
Sbjct: 1781 ADLAQLSGEVEEAAQERR 1798
Score = 34.3 bits (77), Expect = 1.3
Identities = 24/129 (18%), Positives = 60/129 (46%), Gaps = 2/129 (1%)
Query: 805 RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELRAQQEEETRKQQELEA 864
++ Q + E + + E+ +Q K++ ++ E + EAEL A+Q++ + +
Sbjct: 1832 KKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRK 1891
Query: 865 LQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKE--QQELSLTEASLQKLQER 922
++ KE E +++ + + + +L+ +++ +R E +Q+ + A +K Q
Sbjct: 1892 HERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHE 1951
Query: 923 RDQELRRLE 931
D R +
Sbjct: 1952 LDDAEERAD 1960
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,455,555
Number of Sequences: 37866
Number of extensions: 3675955
Number of successful extensions: 76693
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1210
Number of HSP's successfully gapped in prelim test: 1217
Number of HSP's that attempted gapping in prelim test: 21850
Number of HSP's gapped (non-prelim): 20836
length of query: 2058
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1940
effective length of database: 13,779,330
effective search space: 26731900200
effective search space used: 26731900200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.