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Search of human proteins with 154146262
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
(5405 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens] 1.166e+04 0.0
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ... 5465 0.0
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr... 2930 0.0
gi|239757286 PREDICTED: similar to Fc fragment of IgG binding pr... 2726 0.0
gi|239757284 PREDICTED: similar to Fc fragment of IgG binding pr... 1165 0.0
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 878 0.0
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 866 0.0
gi|134268640 tectorin alpha precursor [Homo sapiens] 854 0.0
gi|161019170 mucin 5AC [Homo sapiens] 561 e-159
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 414 e-114
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens] 412 e-114
gi|134031945 SCO-spondin [Homo sapiens] 401 e-110
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 380 e-104
gi|116284392 mucin 2 precursor [Homo sapiens] 366 e-100
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom... 319 4e-86
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom... 319 4e-86
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap... 319 4e-86
gi|151301154 mucin 6, gastric [Homo sapiens] 311 1e-83
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens] 308 7e-83
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens] 308 7e-83
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens] 308 7e-83
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens] 308 7e-83
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens] 308 7e-83
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens] 308 7e-83
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 244 2e-63
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 243 3e-63
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 228 1e-58
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 211 1e-53
gi|37693519 BMP-binding endothelial regulator precursor protein ... 187 2e-46
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 171 1e-41
>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
Length = 5405
Score = 1.166e+04 bits (30254), Expect = 0.0
Identities = 5405/5405 (100%), Positives = 5405/5405 (100%)
Query: 1 MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL 60
MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL
Sbjct: 1 MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL 60
Query: 61 SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA 120
SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA
Sbjct: 61 SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA 120
Query: 121 LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF 180
LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF
Sbjct: 121 LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF 180
Query: 181 NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE 240
NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE
Sbjct: 181 NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE 240
Query: 241 QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR 300
QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR
Sbjct: 241 QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR 300
Query: 301 PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV 360
PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV
Sbjct: 301 PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV 360
Query: 361 VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL 420
VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL
Sbjct: 361 VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL 420
Query: 421 AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY 480
AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY
Sbjct: 421 AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY 480
Query: 481 TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV 540
TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV
Sbjct: 481 TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV 540
Query: 541 SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP 600
SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP
Sbjct: 541 SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP 600
Query: 601 ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC 660
ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC
Sbjct: 601 ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC 660
Query: 661 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA 720
TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA
Sbjct: 661 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA 720
Query: 721 YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC 780
YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC
Sbjct: 721 YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC 780
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS
Sbjct: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL
Sbjct: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV
Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
Query: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG
Sbjct: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
Query: 1021 QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS
Sbjct: 1021 QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
Query: 1081 KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS 1140
KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS
Sbjct: 1081 KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS 1140
Query: 1141 HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP
Sbjct: 1141 HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
Query: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY 1260
GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY
Sbjct: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY 1260
Query: 1261 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 1320
TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL
Sbjct: 1261 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 1320
Query: 1321 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 1380
RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG
Sbjct: 1321 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 1380
Query: 1381 NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED 1440
NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED
Sbjct: 1381 NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED 1440
Query: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI
Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
Query: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
Query: 1561 GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ
Sbjct: 1561 GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
Query: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH
Sbjct: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
Query: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL
Sbjct: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
Query: 1741 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 1800
GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD
Sbjct: 1741 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 1800
Query: 1801 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGS 1860
VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGS
Sbjct: 1801 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGS 1860
Query: 1861 CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILC 1920
CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILC
Sbjct: 1861 CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILC 1920
Query: 1921 KALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCE 1980
KALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCE
Sbjct: 1921 KALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCE 1980
Query: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGS 2040
GPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGS
Sbjct: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGS 2040
Query: 2041 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSA 2100
LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSA
Sbjct: 2041 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSA 2100
Query: 2101 PCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTL 2160
PCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTL
Sbjct: 2101 PCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTL 2160
Query: 2161 PFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPAD 2220
PFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPAD
Sbjct: 2161 PFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPAD 2220
Query: 2221 DLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCH 2280
DLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCH
Sbjct: 2221 DLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCH 2280
Query: 2281 GLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAH 2340
GLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAH
Sbjct: 2281 GLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAH 2340
Query: 2341 SHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYP 2400
SHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYP
Sbjct: 2341 SHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYP 2400
Query: 2401 LGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPH 2460
LGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPH
Sbjct: 2401 LGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPH 2460
Query: 2461 YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT 2520
YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT
Sbjct: 2461 YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT 2520
Query: 2521 LRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVP 2580
LRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVP
Sbjct: 2521 LRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVP 2580
Query: 2581 GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSE 2640
GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSE
Sbjct: 2581 GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSE 2640
Query: 2641 GCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLS 2700
GCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLS
Sbjct: 2641 GCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLS 2700
Query: 2701 ILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCP 2760
ILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCP
Sbjct: 2701 ILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCP 2760
Query: 2761 DGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVC 2820
DGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVC
Sbjct: 2761 DGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVC 2820
Query: 2821 QEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDP 2880
QEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDP
Sbjct: 2821 QEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDP 2880
Query: 2881 HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAA 2940
HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAA
Sbjct: 2881 HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAA 2940
Query: 2941 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV 3000
LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV
Sbjct: 2941 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV 3000
Query: 3001 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 3060
DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG
Sbjct: 3001 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 3060
Query: 3061 SCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL 3120
SCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL
Sbjct: 3061 SCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL 3120
Query: 3121 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVC 3180
CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVC
Sbjct: 3121 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVC 3180
Query: 3181 EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGG
Sbjct: 3181 EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
Query: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS
Sbjct: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
Query: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT
Sbjct: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
Query: 3361 LPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA 3420
LPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA
Sbjct: 3361 LPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA 3420
Query: 3421 DDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPC 3480
DDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPC
Sbjct: 3421 DDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPC 3480
Query: 3481 HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPA 3540
HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPA
Sbjct: 3481 HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPA 3540
Query: 3541 HSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYY 3600
HSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYY
Sbjct: 3541 HSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYY 3600
Query: 3601 PLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDP 3660
PLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDP
Sbjct: 3601 PLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDP 3660
Query: 3661 HYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 3720
HYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF
Sbjct: 3661 HYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 3720
Query: 3721 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV 3780
TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV
Sbjct: 3721 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV 3780
Query: 3781 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 3840
PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS
Sbjct: 3781 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 3840
Query: 3841 AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 3900
AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL
Sbjct: 3841 AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 3900
Query: 3901 SILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQC 3960
SILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQC
Sbjct: 3901 SILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQC 3960
Query: 3961 PDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVV 4020
PDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVV
Sbjct: 3961 PDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVV 4020
Query: 4021 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 4080
CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD
Sbjct: 4021 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 4080
Query: 4081 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 4140
PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA
Sbjct: 4081 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 4140
Query: 4141 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 4200
ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR
Sbjct: 4141 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 4200
Query: 4201 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 4260
VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR
Sbjct: 4201 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 4260
Query: 4261 GSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 4320
GSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI
Sbjct: 4261 GSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 4320
Query: 4321 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAV 4380
LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAV
Sbjct: 4321 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAV 4380
Query: 4381 CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 4440
CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG
Sbjct: 4381 CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 4440
Query: 4441 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 4500
GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL
Sbjct: 4441 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 4500
Query: 4501 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 4560
SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV
Sbjct: 4501 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 4560
Query: 4561 ALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDP 4620
ALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDP
Sbjct: 4561 ALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDP 4620
Query: 4621 ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 4680
ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP
Sbjct: 4621 ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 4680
Query: 4681 CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP 4740
CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP
Sbjct: 4681 CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP 4740
Query: 4741 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRY 4800
AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRY
Sbjct: 4741 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRY 4800
Query: 4801 YPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANG 4860
YPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANG
Sbjct: 4801 YPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANG 4860
Query: 4861 GIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVS 4920
GIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVS
Sbjct: 4861 GIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVS 4920
Query: 4921 LAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRG 4980
LAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRG
Sbjct: 4921 LAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRG 4980
Query: 4981 RLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEE 5040
RLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEE
Sbjct: 4981 RLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEE 5040
Query: 5041 TAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAA 5100
TAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAA
Sbjct: 5041 TAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAA 5100
Query: 5101 CQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDR 5160
CQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDR
Sbjct: 5101 CQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDR 5160
Query: 5161 FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE 5220
FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE
Sbjct: 5161 FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCE 5220
Query: 5221 VKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAE 5280
VKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAE
Sbjct: 5221 VKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAE 5280
Query: 5281 VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLV 5340
VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLV
Sbjct: 5281 VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLV 5340
Query: 5341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDF 5400
RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDF
Sbjct: 5341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDF 5400
Query: 5401 SPCYG 5405
SPCYG
Sbjct: 5401 SPCYG 5405
>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
sapiens]
Length = 3003
Score = 5465 bits (14176), Expect = 0.0
Identities = 2617/3062 (85%), Positives = 2730/3062 (89%), Gaps = 70/3062 (2%)
Query: 1 MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL 60
MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL
Sbjct: 1 MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSL 60
Query: 61 SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA 120
SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA
Sbjct: 61 SESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQA 120
Query: 121 LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF 180
LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF
Sbjct: 121 LNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTF 180
Query: 181 NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE 240
NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE
Sbjct: 181 NGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVE 240
Query: 241 QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR 300
QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR
Sbjct: 241 QLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVR 300
Query: 301 PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV 360
PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV
Sbjct: 301 PSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALV 360
Query: 361 VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL 420
VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL
Sbjct: 361 VAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGL 420
Query: 421 AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY 480
AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY
Sbjct: 421 AKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHY 480
Query: 481 TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV 540
TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV
Sbjct: 481 TTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSV 540
Query: 541 SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP 600
SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP
Sbjct: 541 SLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLP 600
Query: 601 ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC 660
ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC
Sbjct: 601 ARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPAC 660
Query: 661 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA 720
TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA
Sbjct: 661 TPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSA 720
Query: 721 YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC 780
YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC
Sbjct: 721 YAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC 780
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS
Sbjct: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL
Sbjct: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV
Sbjct: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
Query: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG
Sbjct: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
Query: 1021 QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS
Sbjct: 1021 QAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
Query: 1081 KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS 1140
KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS
Sbjct: 1081 KLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS 1140
Query: 1141 HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP
Sbjct: 1141 HYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
Query: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY 1260
GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY
Sbjct: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHY 1260
Query: 1261 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 1320
TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL
Sbjct: 1261 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 1320
Query: 1321 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 1380
RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG
Sbjct: 1321 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 1380
Query: 1381 NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED 1440
NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED
Sbjct: 1381 NYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSED 1440
Query: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI
Sbjct: 1441 CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSI 1500
Query: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD
Sbjct: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD 1560
Query: 1561 GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ
Sbjct: 1561 GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
Query: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH
Sbjct: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
Query: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL
Sbjct: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
Query: 1741 GTNISIHKDEIGKVR--VNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWR 1798
GTNISIHKDEIGKVR VNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWR
Sbjct: 1741 GTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWR 1800
Query: 1799 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 1858
VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR
Sbjct: 1801 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 1860
Query: 1859 GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1918
GSCPTCPEDRLEQYEGPGFCGPLA GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI
Sbjct: 1861 GSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 1920
Query: 1919 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAV 1978
LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCG PCPASCPSPAPLTTPAV
Sbjct: 1921 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAV 1980
Query: 1979 CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 2038
CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG
Sbjct: 1981 CEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 2040
Query: 2039 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLL 2098
GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRF+FQGTCEYLL
Sbjct: 2041 GSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 2100
Query: 2099 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2158
SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV
Sbjct: 2101 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2160
Query: 2159 TLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDP 2218
LPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA SLCGLCGNYNQDP
Sbjct: 2161 ALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDP 2220
Query: 2219 ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 2278
ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP
Sbjct: 2221 ADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 2280
Query: 2279 CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCP 2338
CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL EWRRPDFCP QCP
Sbjct: 2281 CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCP 2340
Query: 2339 AHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRY 2398
AHSHYELCGDSCP SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD RY
Sbjct: 2341 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRY 2400
Query: 2399 YPLGQTFYPGPGCDSLCRCREGGEVSC-EPSSCGPHETCRPSGGSLGCVAVGSTTCQASG 2457
YPLG+ FYPGP C+ C C GG V+C E ++CGPHE CR G C A G C A+G
Sbjct: 2401 YPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANG 2460
Query: 2458 DPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVA 2517
HY T DGR +D G+C YVLAQ C +PG F+++ E A G+ + + V VA
Sbjct: 2461 GIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVA 2515
Query: 2518 NFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRV 2577
+ L Q Q +VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +
Sbjct: 2516 GQVVSLAQGQ-QVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM 2572
Query: 2578 TVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPP 2637
++P + +CGLCGN+NG+ DDF PNGS A + FG +W C
Sbjct: 2573 SIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGC-------- 2624
Query: 2638 GSEGCIPSEECPPELEKK---YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 2694
EGC P + CP L ++ Y+ E CG L +P GP ++C ++ P + C++DLC
Sbjct: 2625 -GEGCGP-QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA 2682
Query: 2695 GGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALS 2754
G+ + LC ++ AY +ACQAAG V+PWR ++FCP+ CP +SHY +C TC C+ALS
Sbjct: 2683 QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALS 2742
Query: 2755 APLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHV 2814
C C EGC+CD FL + C+P+Q CGC HNG Y ++L +C ++C+C
Sbjct: 2743 GLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSS 2802
Query: 2815 GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATC 2874
+ CQ C PG+VC+ +C +G+C+ + A
Sbjct: 2803 SSGLTCQAAGCPPGRVCEVKAEARNC-------------------WATRGLCVLSVGA-- 2841
Query: 2875 WLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVS 2931
+ +FDG + Y L++ CPG+ Q P + V + Q + AV
Sbjct: 2842 ------NLTTFDGARGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVG 2892
Query: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD-FGL 2990
V + + T ++ +K V VNG+ LP +SV++ +LLV G+
Sbjct: 2893 QVHIFFQDGMVT-LTPNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGV 2946
Query: 2991 QVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGW 3050
QV N +V V + + + G +CG CGN D + ND + + P++ WRA +
Sbjct: 2947 QVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDF 3000
Query: 3051 DP 3052
P
Sbjct: 3001 SP 3002
Score = 4486 bits (11635), Expect = 0.0
Identities = 2101/2570 (81%), Positives = 2214/2570 (86%), Gaps = 24/2570 (0%)
Query: 2846 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 2905
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 502
Query: 2906 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 2965
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 503 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
Query: 2966 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 3025
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
Query: 3026 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 3085
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 621 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 679
Query: 3086 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 3145
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 739
Query: 3146 GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 3204
C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 740 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 796
Query: 3205 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 3263
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 797 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 854
Query: 3264 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 3323
GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V V NEHRG
Sbjct: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 913
Query: 3324 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTT 3382
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 914 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 973
Query: 3383 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 3434
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 974 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1033
Query: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 3494
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 1034 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1092
Query: 3495 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 3554
D C + G G LC A+ATY AACQAAGA + WR + CP CP HSHYE C CP S
Sbjct: 1093 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1152
Query: 3555 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 3614
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H Y+P GQTFYPGPGCDS
Sbjct: 1153 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1212
Query: 3615 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMG 3674
LC C+EGG VSCE SSCGPHE C+PSGGSLGCVAVGS+TCQASGDPHYTTFDG RFDFMG
Sbjct: 1213 LCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMG 1272
Query: 3675 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN 3734
TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN
Sbjct: 1273 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN 1332
Query: 3735 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 3794
GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ MCGLCGN
Sbjct: 1333 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGN 1392
Query: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELE 3854
YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP CPPGS CIPS KCPPELE
Sbjct: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELE 1452
Query: 3855 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 3914
KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC
Sbjct: 1453 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 1512
Query: 3915 QAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGF 3974
QAAGGHVEPWR ETFCPMECP NSHYELCADTCSLGCSALSAP QC DGCAEGCQCDSGF
Sbjct: 1513 QAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGF 1572
Query: 3975 LYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQP 4034
LYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCH GK +VCQEHSCKPGQVCQP
Sbjct: 1573 LYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQP 1632
Query: 4035 SGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 4094
SGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ
Sbjct: 1633 SGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 1692
Query: 4095 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 4154
GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG
Sbjct: 1693 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 1752
Query: 4155 KVRV--NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 4212
KVRV NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 1753 KVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 1812
Query: 4213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 4272
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 1813 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 1872
Query: 4273 QYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 4332
QYEGPGFCGPL+SGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC
Sbjct: 1873 QYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 1932
Query: 4333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 4392
QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 1933 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 1992
Query: 4393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 4452
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 1993 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2052
Query: 4453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 4512
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE
Sbjct: 2053 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 2112
Query: 4513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 4572
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA
Sbjct: 2113 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 2172
Query: 4573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 4632
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 2173 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
Query: 4633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 4692
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 2233 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 2292
Query: 4693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 4752
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC
Sbjct: 2293 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 2352
Query: 4753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 4812
PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE
Sbjct: 2353 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 2412
Query: 4813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 4872
CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY
Sbjct: 2413 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 2472
Query: 4873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE 4932
DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE
Sbjct: 2473 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE 2532
Query: 4933 AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN 4992
AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN
Sbjct: 2533 AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN 2592
Query: 4993 WSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ 5052
WSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ
Sbjct: 2593 WSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ 2652
Query: 5053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR 5112
LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR
Sbjct: 2653 LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR 2712
Query: 5113 TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ 5172
TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ
Sbjct: 2713 TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ 2772
Query: 5173 DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR 5232
DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR
Sbjct: 2773 DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR 2832
Query: 5233 GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG 5292
GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG
Sbjct: 2833 GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG 2892
Query: 5293 QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA 5352
QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA
Sbjct: 2893 QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA 2952
Query: 5353 NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP 5402
NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP
Sbjct: 2953 NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP 3002
Score = 3559 bits (9229), Expect = 0.0
Identities = 1713/2627 (65%), Positives = 1938/2627 (73%), Gaps = 86/2627 (3%)
Query: 1645 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 1704
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 502
Query: 1705 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 1764
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 503 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
Query: 1765 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 1824
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
Query: 1825 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 1884
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 621 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 679
Query: 1885 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 1944
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 739
Query: 1945 GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 2003
C ++CP NS YE+CG CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 740 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 796
Query: 2004 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 2062
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 797 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 854
Query: 2063 GCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2122
GC P CQ GDPHYV+ DG RF+F GTC YLL C G F V V NEHRG
Sbjct: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 913
Query: 2123 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTT 2181
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 914 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 973
Query: 2182 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 2233
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 974 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1033
Query: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2293
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 1034 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1092
Query: 2294 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 2353
D C + G G LC A+ATY AACQAAGA + WR + CP CP HSHYE C CP S
Sbjct: 1093 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1152
Query: 2354 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 2413
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H Y+P GQTFYPGPGCDS
Sbjct: 1153 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1212
Query: 2414 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMG 2473
LC C+EGG VSCE SSCGPHE C+PSGGSLGCVAVGS+TCQASGDPHYTTFDGRRFDFMG
Sbjct: 1213 LCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMG 1272
Query: 2474 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN 2533
TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN
Sbjct: 1273 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVN 1332
Query: 2534 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 2593
GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ MCGLCGN
Sbjct: 1333 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGN 1392
Query: 2594 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELE 2653
YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP CPPGSE CIPS +CPPELE
Sbjct: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELE 1452
Query: 2654 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713
KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC
Sbjct: 1453 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 1512
Query: 2714 QAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGF 2773
QAAGG VEPWR ETFCPMECP NSHYELCADTCSLGCSALSAP QC DGCAEGCQCDSGF
Sbjct: 1513 QAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGF 1572
Query: 2774 LYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQP 2833
LYNGQACVPIQQCGCYHNG YYEPEQTVLIDNCRQQCTCH GK +VCQEHSCKPGQVCQP
Sbjct: 1573 LYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQP 1632
Query: 2834 SGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 2893
SGGILSCV KDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ
Sbjct: 1633 SGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 1692
Query: 2894 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 2953
GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG
Sbjct: 1693 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 1752
Query: 2954 KVR--VNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 3011
KVR VNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 1753 KVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 1812
Query: 3012 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 3071
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 1813 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 1872
Query: 3072 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 3131
QYEGPGFCGPLA GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC
Sbjct: 1873 QYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 1932
Query: 3132 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 3191
QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 1933 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 1992
Query: 3192 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 3251
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 1993 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2052
Query: 3252 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 3311
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE
Sbjct: 2053 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 2112
Query: 3312 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHA 3371
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV LPFQLDSLLHA
Sbjct: 2113 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 2172
Query: 3372 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 3431
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA SLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 2173 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
Query: 3432 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 3491
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 2233 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 2292
Query: 3492 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 3551
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL EWRRPDFCP QCPAHSHYELCGDSC
Sbjct: 2293 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 2352
Query: 3552 PGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPG 3611
P SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD RYYPLG+ FYPGP
Sbjct: 2353 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 2412
Query: 3612 CDSLCRCREGGEVSC-EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRF 3670
C+ C C GG V+C E ++CGPHE CR G C A G C A+G HY T DG +
Sbjct: 2413 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 2472
Query: 3671 DFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 3730
D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +
Sbjct: 2473 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-Q 2526
Query: 3731 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCG 3790
VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +++P + +CG
Sbjct: 2527 VTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 2584
Query: 3791 LCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCP 3850
LCGN+NG+ DDF PNGS A + FG +W C P G C+ + P
Sbjct: 2585 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGC-GEGCGPQGCPVCLAEETAP 2643
Query: 3851 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 3910
Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ AY
Sbjct: 2644 ------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAY 2697
Query: 3911 VSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQC 3970
+ACQAAG V+PWR ++FCP+ CP +SHY +C TC C+ALS C C EGC+C
Sbjct: 2698 TAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCEC 2757
Query: 3971 DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 4030
D FL + C+P+Q CGC HNG Y ++L +C ++C+C + CQ C PG+
Sbjct: 2758 DDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGR 2817
Query: 4031 VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 4090
VC+ +C +G+C+ + A + +FDG +
Sbjct: 2818 VCEVKAEARNC-------------------WATRGLCVLSVGA--------NLTTFDGAR 2850
Query: 4091 FDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAALGTNIS 4147
Y L++ CPG+ Q P + V + Q + AV V + + T ++
Sbjct: 2851 GATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVT-LT 2906
Query: 4148 IHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVAD-FGLQVSYDWNWRVDVTLP 4206
+K V VNG+ LP +SV++ +LLV G+QV N +V V +
Sbjct: 2907 PNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVS 2961
Query: 4207 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 4253
+ + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 2962 NDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 3002
Score = 1172 bits (3033), Expect = 0.0
Identities = 687/1850 (37%), Positives = 950/1850 (51%), Gaps = 139/1850 (7%)
Query: 3623 EVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQ 3682
E SCE C + C+ GG GCVA + C+A GDPHYTTFDG R+D MGTC Y + +
Sbjct: 441 EPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE 500
Query: 3683 TCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 3741
C L F+V +N G+ RVS ++TV+ + ++ L + + V V+ +LP
Sbjct: 501 LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
Query: 3742 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKD 3801
V L+ G++R Q G V+E FGL V YD + +++P + +CGLCGNYNGDP D
Sbjct: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
Query: 3802 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEE 3861
DF P+G+ A +A EF +SW+ + D L C G P+ C P + Y+ +
Sbjct: 621 DFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYEGDR 672
Query: 3862 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHV 3921
CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G V
Sbjct: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
Query: 3922 EPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQA 3980
WR+ CP+ CP NS YELC C C+ +AP C C EGC C GF+ +G A
Sbjct: 733 GDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGA 792
Query: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDN-CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGIL 4039
CVP CGC G+ P Q V D C+++CTC+ + +C+ Q C P+G
Sbjct: 793 CVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCN----GATHQVTCRDKQSC-PAG--- 844
Query: 4040 SCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNY 4099
E C Q G C P+ TC GDPHY SFDGR+FDF GTC Y
Sbjct: 845 ----------------ERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTY 888
Query: 4100 VLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVN 4159
+L G G L F V +N++RG+ VSY R V V A G +++ ++ G+V V+
Sbjct: 889 LL--VGSCG-QNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVD 945
Query: 4160 GVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 4219
VL LP ADG++ V + A++ DFGL V+YDWN RV +PSSY A+CGLCGN
Sbjct: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
Query: 4220 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGF 4279
+ +P +D G A + +G SW+ P C G CP +Q +
Sbjct: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNE 1064
Query: 4280 CGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVI 4339
CG L+ GPF CH+ + P+ + CV D C+ G LC ALA+Y AACQAAG +
Sbjct: 1065 CGILAD-PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATV 1123
Query: 4340 EDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA 4399
WR++ C ++CP +SHYE C CP SC L P C C EGC CD GF LS
Sbjct: 1124 HPWRSEELCPLSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSECHEGCVCDEGFALSG 1180
Query: 4400 DRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLL 4459
+ C+PL + CGC GTYH G F+ C C C GG + C +SCG E C
Sbjct: 1181 ESCLPLAS-CGCVHQGTYHPPGQTFYPGPGCDSLCHC-QEGGLVSCESSSCGPHEAC--Q 1236
Query: 4460 PS-GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTV 4518
PS G GC V ++ CQA GDPHY T DG RFDF GTC Y+L+ C P G F V
Sbjct: 1237 PSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQ 1295
Query: 4519 ANEHRGSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDGVFVALPFQL-DSLLHAHLSG 4576
N G+ VS TR +T+Q+ N +L L R W K+ V+GV + LP L + + A G
Sbjct: 1296 ENVAWGNGRVSVTRVITVQVANFTLRLEQRQW--KVTVNGVDMKLPVVLANGQIRASQHG 1353
Query: 4577 ADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQV 4636
+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD + KP G Q
Sbjct: 1354 SDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ----KPNGSQA 1409
Query: 4637 GGAQGCGE----------CV-SKPCP---------SPCTPEQQESFGGPDACGVISATDG 4676
G A G C+ PCP C PE ++ + + CG++S+ G
Sbjct: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
Query: 4677 PLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCP 4736
PL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + WR FCP
Sbjct: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
Query: 4737 LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH 4796
++CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+ QCGC H
Sbjct: 1530 MECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYH 1589
Query: 4797 DGRYY-PLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGV------QACH 4849
+G YY P V C ++C C G + CQE +C P + C+ G+ CH
Sbjct: 1590 NGVYYEPEQTVLI--DNCRQQCTCHAGKGMVCQE-HSCKPGQVCQPSGGILSCVTKDPCH 1646
Query: 4850 ATGC------------GRCLAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP- 4888
C G CL N G HY + DGR +D G+C+YVLA P
Sbjct: 1647 GVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPG 1706
Query: 4889 --KPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ----QVTVDGEAVALP 4937
G F++ + G+ ++ + V G +S+ + + +V V+G ALP
Sbjct: 1707 VSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALP 1766
Query: 4938 VAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSD 4995
V+V GR+ V +L GL++ +D + + +++PS + G +CGLCGN + N ++
Sbjct: 1767 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 1826
Query: 4996 DFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRN 5055
D V PNG+ A S+ +G +WRAPG C + C CP C + YE CG L +
Sbjct: 1827 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC-RGSCPTCPEDRLEQYEGPGFCGPLAS 1885
Query: 5056 -PQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTD 5114
GPF TC A + P +F+ CV D+C GD+ LC++LA+Y AACQAAGV ++ WR
Sbjct: 1886 GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQ 1945
Query: 5115 SFCPLHCPAHSHYSICTRTCQGSCAALSGLTG---CTTRCFEGCECDDRFLLSQGVCIPV 5171
C + CP +SHY +C C SC + + LT C C EGC+CD F+LS C+P+
Sbjct: 1946 VGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPL 2005
Query: 5172 QD-CGCTHNGRYLPVNSSL-LTSDCSERCSCSSSSG-LTCQAAGCPPGRVCEVKAEARN- 5227
+ CGC NG Y S CS+ C C G L C A C G VC + ++
Sbjct: 2006 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHG 2065
Query: 5228 CW-ATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHG 5286
C + C + T DG R Y LS+ C G + V + H
Sbjct: 2066 CQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE--HR 2123
Query: 5287 KTEAVG---QVHIFFQDGMVTLTPN--KGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVR 5341
++AV V + + +TL+ + + V+G+ V LP + L S+ + ++V
Sbjct: 2124 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQ-LDSLLHAHLSGADVVVT 2182
Query: 5342 QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA 5391
+G+ + + V + V +A LCG CGN++ D +D KPA
Sbjct: 2183 TTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 2232
>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1403
Score = 2930 bits (7595), Expect = 0.0
Identities = 1355/1370 (98%), Positives = 1360/1370 (99%)
Query: 4033 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 4092
QP +L ++ DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD
Sbjct: 33 QPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 92
Query: 4093 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 4152
FQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVAALGTNISIHKDE
Sbjct: 93 FQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
Query: 4153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 4212
IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 212
Query: 4213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 4272
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 272
Query: 4273 QYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 4332
QYEGPGFCGPL+ GTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD DILCKALASYVAAC
Sbjct: 273 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAAC 332
Query: 4333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 4392
QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 392
Query: 4393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 4452
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 452
Query: 4453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 4512
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE
Sbjct: 453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 512
Query: 4513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 4572
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA
Sbjct: 513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 572
Query: 4573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 4632
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 632
Query: 4633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 4692
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 692
Query: 4693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 4752
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC
Sbjct: 693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
Query: 4753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 4812
PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE
Sbjct: 753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 812
Query: 4813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 4872
CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY
Sbjct: 813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 872
Query: 4873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE 4932
DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE
Sbjct: 873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGE 932
Query: 4933 AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN 4992
AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN
Sbjct: 933 AVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGN 992
Query: 4993 WSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ 5052
WSDDFVLPNGSAASSVETFGAAWR PGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ
Sbjct: 993 WSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQ 1052
Query: 5053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR 5112
LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR
Sbjct: 1053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR 1112
Query: 5113 TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ 5172
TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ
Sbjct: 1113 TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQ 1172
Query: 5173 DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR 5232
DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR
Sbjct: 1173 DCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR 1232
Query: 5233 GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG 5292
GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG
Sbjct: 1233 GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG 1292
Query: 5293 QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA 5352
QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA
Sbjct: 1293 QVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGA 1352
Query: 5353 NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP 5402
NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP
Sbjct: 1353 NGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSP 1402
Score = 2019 bits (5231), Expect = 0.0
Identities = 977/1428 (68%), Positives = 1092/1428 (76%), Gaps = 64/1428 (4%)
Query: 2832 QPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 2891
QP +L ++ DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD
Sbjct: 33 QPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 92
Query: 2892 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 2951
FQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVAALGTNISIHKDE
Sbjct: 93 FQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
Query: 2952 IGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 3011
IGKVRVNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 212
Query: 3012 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 3071
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 272
Query: 3072 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 3131
QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD DILCKALASYVAAC
Sbjct: 273 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAAC 332
Query: 3132 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 3191
QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 392
Query: 3192 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 3251
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 452
Query: 3252 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 3311
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE
Sbjct: 453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 512
Query: 3312 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHA 3371
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV LPFQLDSLLHA
Sbjct: 513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 572
Query: 3372 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 3431
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA SLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 632
Query: 3432 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 3491
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 692
Query: 3492 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 3551
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL EWRRPDFCP QCPAHSHYELCGDSC
Sbjct: 693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
Query: 3552 PGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPG 3611
P SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD RYYPLG+ FYPGP
Sbjct: 753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 812
Query: 3612 CDSLCRCREGGEVSC-EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRF 3670
C+ C C GG V+C E ++CGPHE CR G C A G C A+G HY T DG +
Sbjct: 813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 872
Query: 3671 DFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 3730
D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +
Sbjct: 873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-Q 926
Query: 3731 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCG 3790
VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +++P + +CG
Sbjct: 927 VTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 984
Query: 3791 LCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTC-PPGSAGCIPSDKC 3849
LCGN+NG+ DDF PNGS A + FG +W VP S C P G C+ +
Sbjct: 985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCLAEETA 1042
Query: 3850 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 3909
P Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ A
Sbjct: 1043 P------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAA 1096
Query: 3910 YVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQ 3969
Y +ACQAAG V+PWR ++FCP+ CP +SHY +C TC C+ALS C C EGC+
Sbjct: 1097 YTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
Query: 3970 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPG 4029
CD FL + C+P+Q CGC HNG Y ++L +C ++C+C + CQ C PG
Sbjct: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
Query: 4030 QVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGR 4089
+VC+ +C +G+C+ + A + +FDG
Sbjct: 1217 RVCEVKAEARNC-------------------WATRGLCVLSVGA--------NLTTFDGA 1249
Query: 4090 KFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAALGTNI 4146
+ Y L++ CPG+ Q P + V + Q + AV V + + T +
Sbjct: 1250 RGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVT-L 1305
Query: 4147 SIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVAD-FGLQVSYDWNWRVDVTL 4205
+ +K V VNG+ LP +SV++ +LLV G+QV N +V V +
Sbjct: 1306 TPNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIV 1360
Query: 4206 PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 4253
+ + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 1361 SNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 1402
Score = 2018 bits (5229), Expect = 0.0
Identities = 977/1428 (68%), Positives = 1092/1428 (76%), Gaps = 64/1428 (4%)
Query: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
QP +L ++ DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD
Sbjct: 33 QPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 92
Query: 1691 FQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDE 1750
FQGTCNYVLATTGC GVSTQGLTPFTVTTKN+NRGNPAVSYVRVVTVAALGTNISIHKDE
Sbjct: 93 FQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDE 152
Query: 1751 IGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 1810
IGKVRVNGVLTALPVSVADGRISV QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA
Sbjct: 153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 212
Query: 1811 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 1870
VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE
Sbjct: 213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE 272
Query: 1871 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAAC 1930
QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGD DILCKALASYVAAC
Sbjct: 273 QYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAAC 332
Query: 1931 QAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCD 1990
QAAGVVIEDWRAQVGCEITCPENSHYEVCG PCPASCPSPAPLTTPAVCEGPCVEGCQCD
Sbjct: 333 QAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCD 392
Query: 1991 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2050
AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL
Sbjct: 393 AGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 452
Query: 2051 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAE 2110
GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRF+FQGTCEYLLSAPCHGPPLGAE
Sbjct: 453 GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAE 512
Query: 2111 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHA 2170
NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV LPFQLDSLLHA
Sbjct: 513 NFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHA 572
Query: 2171 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 2230
HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA SLCGLCGNYNQDPADDLKAVGGKPA
Sbjct: 573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 632
Query: 2231 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 2290
GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ
Sbjct: 633 GWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQ 692
Query: 2291 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 2350
GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL EWRRPDFCP QCPAHSHYELCGDSC
Sbjct: 693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 752
Query: 2351 PGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPG 2410
P SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD RYYPLG+ FYPGP
Sbjct: 753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 812
Query: 2411 CDSLCRCREGGEVSC-EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRF 2469
C+ C C GG V+C E ++CGPHE CR G C A G C A+G HY T DGR +
Sbjct: 813 CERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVY 872
Query: 2470 DFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 2529
D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +
Sbjct: 873 DLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-Q 926
Query: 2530 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCG 2589
VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +++P + +CG
Sbjct: 927 VTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 984
Query: 2590 LCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTC-PPGSEGCIPSEEC 2648
LCGN+NG+ DDF PNGS A + FG +W VP S C P G C+ E
Sbjct: 985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCLAEETA 1042
Query: 2649 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 2708
P Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ A
Sbjct: 1043 P------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAA 1096
Query: 2709 YVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQ 2768
Y +ACQAAG V+PWR ++FCP+ CP +SHY +C TC C+ALS C C EGC+
Sbjct: 1097 YTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCE 1156
Query: 2769 CDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPG 2828
CD FL + C+P+Q CGC HNG Y ++L +C ++C+C + CQ C PG
Sbjct: 1157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 1216
Query: 2829 QVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGR 2888
+VC+ +C +G+C+ + A + +FDG
Sbjct: 1217 RVCEVKAEARNC-------------------WATRGLCVLSVGA--------NLTTFDGA 1249
Query: 2889 KFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAALGTNI 2945
+ Y L++ CPG+ Q P + V + Q + AV V + + T +
Sbjct: 1250 RGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVT-L 1305
Query: 2946 SIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD-FGLQVSYDWNWRVDVTL 3004
+ +K V VNG+ LP +SV++ +LLV G+QV N +V V +
Sbjct: 1306 TPNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIV 1360
Query: 3005 PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 3052
+ + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 1361 SNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 1402
Score = 1025 bits (2649), Expect = 0.0
Identities = 554/1433 (38%), Positives = 776/1433 (54%), Gaps = 88/1433 (6%)
Query: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 41 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 98
Query: 496 YTMVE---LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 552
Y + L L F+V KNE+RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 99 YVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 158
Query: 553 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 612
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 159 NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 218
Query: 613 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDR 672
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 219 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPG 278
Query: 673 LCGMLTK-LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGIS 731
CG L GPF CH + P F + CV D+C+ GG+ LC+ L++Y AC G+
Sbjct: 279 FCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVV 338
Query: 732 VGDWRSPANCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVA 788
+ DWR+ C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV
Sbjct: 339 IEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVL 397
Query: 789 SGGACVPASS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 847
S CVP ++ CGC G G E WAD C + C C + C SC GE C
Sbjct: 398 SADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVC 456
Query: 848 SV-QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRV 905
+ +G GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V
Sbjct: 457 GLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTV 516
Query: 906 LVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQ 965
V NEHRGSQ VSYTR+V ++ + + +P ++ VD V LPFQ D +
Sbjct: 517 TVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLS 575
Query: 966 GRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANA 1025
G D VV T GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A
Sbjct: 576 GADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG-- 633
Query: 1026 LAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDP 1084
WQ GCG CP + Q+ + CG+++ GP CH + P
Sbjct: 634 ------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPP 687
Query: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
+ C+ D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE
Sbjct: 688 AQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYEL 747
Query: 1145 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTF 1204
C CP+SC L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ F
Sbjct: 748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 807
Query: 1205 YPGPGCDSLCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTF 1263
YPGP C+ C C GG V+C E ++CGPHE C+ G C A G C A+G HY T
Sbjct: 808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITL 867
Query: 1264 DGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE 1323
DGR +D G+C YVLAQ C +PG F+++ E A G+ + + V VA + L
Sbjct: 868 DGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLA 922
Query: 1324 QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 1383
Q Q +VTV+G + LPV A G++R + G ++V++T GLR+ +D ++ +++P +
Sbjct: 923 QGQ-QVTVDGEAVALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 979
Query: 1384 QQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPC-PPGSEDCI 1442
++CGLCGN+NG+ DDF PNGS A + FG +W VP S C P G C+
Sbjct: 980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR--VPGSSKGCGEGCGPQGCPVCL 1037
Query: 1443 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILC 1502
P Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC
Sbjct: 1038 AEETAP------YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 1091
Query: 1503 SNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGC 1562
++ AY +ACQAAG V+PWRT++FCP+ CP +SHY +C TC C+ALS C C
Sbjct: 1092 RSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRC 1151
Query: 1563 AEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH 1622
EGC+CD FL + C+P+Q CGC HNG Y ++L +C ++C+C + G+ CQ
Sbjct: 1152 FEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAA 1211
Query: 1623 SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 1682
C PG+VC+ +C +G+C+ + A +
Sbjct: 1212 GCPPGRVCEVKAEARNC-------------------WATRGLCVLSVGA--------NLT 1244
Query: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP-FTVTTKNQ--NRGNPAVSYVRVVTVAA 1739
+FDG + Y L++ CPG+ Q P + V + Q + AV V +
Sbjct: 1245 TFDGARGATTSPGVYELSSR-CPGL--QNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDG 1301
Query: 1740 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVAD-FGLQVSYDWNWR 1798
+ T ++ +K V VNG+ LP +SV++ +LLV G+QV N +
Sbjct: 1302 MVT-LTPNKG----VWVNGLRVDLPAEKL-ASVSVSRTPDGSLLVRQKAGVQVWLGANGK 1355
Query: 1799 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDP 1851
V V + + + G +CG CGN D + ND + + P++ WRA + P
Sbjct: 1356 VAVIVSNDHAGKLCGACGNFDGDQTND--WHDSQEKPAME----KWRAQDFSP 1402
Score = 904 bits (2336), Expect = 0.0
Identities = 520/1407 (36%), Positives = 725/1407 (51%), Gaps = 98/1407 (6%)
Query: 2425 CEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-C 2483
C +C P ETC+ GG C+ TC GDPHY +FDGR+FDF GTC YVLA T C
Sbjct: 47 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 106
Query: 2484 --GTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 2540
+ GL F V +N GN VS RV+TV + + + + KV VNGV LP
Sbjct: 107 LGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 166
Query: 2541 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKD 2600
V +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P +
Sbjct: 167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 226
Query: 2601 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEE 2660
D PNG+ A + +G SW D P C G P+ CP + ++Y+
Sbjct: 227 DQVFPNGTLAPSIPIWGGSWRAPGWD------PLCWDECRGSCPT--CPEDRLEQYEGPG 278
Query: 2661 FCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQ 2719
FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQAAG
Sbjct: 279 FCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVV 338
Query: 2720 VEPWRNETFCPMECPQNSHYELCADTCSLGCSA---LSAPLQCPDGCAEGCQCDSGFLYN 2776
+E WR + C + CP+NSHYE+C C C + L+ P C C EGCQCD+GF+ +
Sbjct: 339 IEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS 398
Query: 2777 GQACVPIQQ-CGCYHNGAYYEPEQTVLIDN-CRQQCTCHVGK-VVVCQEHSCKPGQVCQP 2833
CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+VC
Sbjct: 399 ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVC-- 456
Query: 2834 SGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQ 2893
G+L GQ C P A C WGDPHY + DG +FDFQ
Sbjct: 457 --GLLP---------------------SGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQ 493
Query: 2894 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 2953
GTC Y+L+ C G G FTVT N++RG+ AVSY R VT+ ++++
Sbjct: 494 GTCEYLLSAP-CHGPPL-GAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPR 551
Query: 2954 KVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 3013
K++V+GV ALP + D + + ++ GL +++D + V + +P++Y ++C
Sbjct: 552 KLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLC 610
Query: 3014 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQ 3072
GLCGN +++P +D G A W+ G C + CP+ C ++ E
Sbjct: 611 GLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQG-CGECVSKPCPSPCTPEQQES 661
Query: 3073 YEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQ 3132
+ GP CG ++ T GP CH VPP +F+GC+LD C G LC A+A+YVAACQ
Sbjct: 662 FGGPDACGVIS-ATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 720
Query: 3133 AAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDA 3192
AAG + +WR C + CP +SHYE+CG CP SCPS L+ P CE C EGC CDA
Sbjct: 721 AAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS---LSAPEGCESACREGCVCDA 777
Query: 3193 GFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLG 3252
GFVLS D CVP+ CGC +G Y+ G F+ C + C CGPGG A+CG
Sbjct: 778 GFVLSGDTCVPVGQ-CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPH 836
Query: 3253 EVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAEN 3312
E C L G C C A G HY+TLDG +D G+C Y+L+ CH P G E+
Sbjct: 837 EECRL-EDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKP-GDED 894
Query: 3313 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAH 3372
F++ + G L + +S +++ VDG V LP + +
Sbjct: 895 FSIVLEKNAAGDLQ-------RLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRV-RVT 946
Query: 3373 LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG 3432
G ++V+ TT GL L FDGD+ + + +P+ + G LCGLCGN+N + +DD G A
Sbjct: 947 AEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAAS 1006
Query: 3433 --------WQV-GGAQGCGE-CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHG 3482
W+V G ++GCGE C + CP C E+ + +ACG + GP A C
Sbjct: 1007 SVETFGAAWRVPGSSKGCGEGCGPQGCPV-CLAEETAPYESNEACGQLRNPQGPFATCQA 1065
Query: 3483 LVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS 3542
++ P++YF+ C+ D C +G LC ++A Y AACQAAG ++ WR FCP CPAHS
Sbjct: 1066 VLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS 1125
Query: 3543 HYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPL 3602
HY +C +C GSC +LS GC + C EGC CD F+LS C+PV CGC H+ RY P+
Sbjct: 1126 HYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPV 1185
Query: 3603 GQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHY 3662
+ C C C ++C+ + C P C + C A C S +
Sbjct: 1186 NSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGL-CVLSVGANL 1243
Query: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRF-----AVLQENVAWGNGRVSVTRVITVQV 3717
TTFDG R VY L+ C PGL V + + G I Q
Sbjct: 1244 TTFDGARGATTSPGVYELSSRC---PGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD 1300
Query: 3718 ANFTLRLEQRQWKVTVNGVDMKLPVV-LANGQIRASQHGSDVVIETDFGLRVAYDLVYYV 3776
TL + W VNG+ + LP LA+ + + GS +++ G++V V
Sbjct: 1301 GMVTLTPNKGVW---VNGLRVDLPAEKLASVSVSRTPDGS-LLVRQKAGVQVWLGANGKV 1356
Query: 3777 RVTVPGNYYQLMCGLCGNYNGDPKDDF 3803
V V ++ +CG CGN++GD +D+
Sbjct: 1357 AVIVSNDHAGKLCGACGNFDGDQTNDW 1383
Score = 889 bits (2296), Expect = 0.0
Identities = 530/1425 (37%), Positives = 729/1425 (51%), Gaps = 106/1425 (7%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H VTCR + E C Q G C P+ TC GDPHY SFDGR+FDF GTC Y+L
Sbjct: 48 HGVTCRPQ------ETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVL 101
Query: 891 V--GSCGQNA-ALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDV 947
G G + L F V +NE+RG+ VSY R V V A G +++ ++ G+V V+ V
Sbjct: 102 ATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGV 161
Query: 948 LQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFN 1007
L LP ADG++ V + A++ DFGL V+YDWN RV +PSSY A+CGLCGN +
Sbjct: 162 LTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMD 221
Query: 1008 GDPADDLALRGGGQAANALAFGNSWQEET-RPGCGATEPGDCPKLDSLVAQQLQSKNECG 1066
+P +D G A + +G SW+ P C G CP +Q + CG
Sbjct: 222 RNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 281
Query: 1067 ILADPKG-PFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHP 1125
LA G PF CH+ + P+ + CV D C+ G LC ALA+Y AACQAAG +
Sbjct: 282 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIED 341
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSECHEGCVCDEGFALSGES 1182
WR++ C ++CP +SHYE C CP SC L P C C EGC CD GF LS +
Sbjct: 342 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADR 401
Query: 1183 CLPLAS-CGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG-LVSCESSSCGPHEACQ--PS 1238
C+PL + CGC GTYH G F+ C C C GG + C +SCG E C PS
Sbjct: 402 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 461
Query: 1239 GGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQEN 1297
G GC V ++ CQA GDPHY T DG RFDF GTC Y+L+ C P G F V N
Sbjct: 462 GQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVAN 520
Query: 1298 VAWGNGRVSVTRVITVQVANFTLRLEQRQW--KVTVNGVDMKLPVVLANGQIRASQHGSD 1355
G+ VS TR +T+Q+ N +L L R W K+ V+GV + LP L + + A G+D
Sbjct: 521 EHRGSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDGVFVALPFQL-DSLLHAHLSGAD 578
Query: 1356 VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ----KPNGSQAGN 1411
VV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD + KP G Q G
Sbjct: 579 VVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGG 638
Query: 1412 ANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPL 1471
A G + PCP C PE ++ + + CG++S+ GPL
Sbjct: 639 AQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACGVISATDGPL 678
Query: 1472 SSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPME 1531
+ CH LV P + C+ D C G+ LC + YV+ACQAAG + WR FCP++
Sbjct: 679 APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQ 738
Query: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+ QCGC H+G
Sbjct: 739 CPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDG 798
Query: 1592 VYYEPEQTVLID-NCRQQCTCHAGKGMVCQEHS-CKPGQVCQPSGGILSCVTKDPCHGVT 1649
YY + C ++C C G + CQE + C P + C+ G+ +C H
Sbjct: 799 RYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQAC------HATG 852
Query: 1650 CRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVST 1709
C G CL N G HY + DGR +D G+C+YVLA P
Sbjct: 853 C------------GRCLAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP---K 889
Query: 1710 QGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVAD 1769
G F++ + G+ ++ + V G +S+ + + +V V+G ALPV+V
Sbjct: 890 PGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV-- 940
Query: 1770 GRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 1829
GR+ VT +L GL++ +D + + +++PS + G +CGLCGN + N ++D V P
Sbjct: 941 GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLP 1000
Query: 1830 NGTLAPSIPIWGGSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
NG+ A S+ +G +WR PG C + C CP C + YE CG L GP
Sbjct: 1001 NGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLR-NPQGP 1059
Query: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
F TC A + P +F+ CV D+C GD+ LC++LA+Y AACQAAGV ++ WR C +
Sbjct: 1060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL 1119
Query: 1949 TCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 2008
CP +SHY +C C SC + + LT C C EGC+CD F+LS C+P+ + CG
Sbjct: 1120 HCPAHSHYSICTRTCQGSCAALSGLTG---CTTRCFEGCECDDRFLLSQGVCIPVQD-CG 1175
Query: 2009 CWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS 2068
C NG Y S CS+ C C G L C A C G VC + ++ C +
Sbjct: 1176 CTHNGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQAAGCPPGRVCEVKAEARN-CW-AT 1231
Query: 2069 TAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANE--HRGSQAV 2126
C + T DG R Y LS+ C G + V + H ++AV
Sbjct: 1232 RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAV 1291
Query: 2127 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQ-LDSLLHAHLSGADVVVTTTSGL 2185
V + + +TL+ + + V+G+ V LP + L S+ + ++V +G+
Sbjct: 1292 G---QVHIFFQDGMVTLTPN--KGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGV 1346
Query: 2186 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 2230
+ + V + V +AG LCG CGN++ D +D KPA
Sbjct: 1347 QVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA 1391
Score = 869 bits (2246), Expect = 0.0
Identities = 523/1422 (36%), Positives = 729/1422 (51%), Gaps = 110/1422 (7%)
Query: 2043 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP- 2101
C +C E C GQ C P A C WGDPHY + DG +F+FQGTC Y+L+
Sbjct: 47 CHGVTCRPQETCKE-QGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTG 105
Query: 2102 CHGPPL-GAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTL 2160
C G G FTVT NE+RG+ AVSY R VT+ ++++ K++V+GV L
Sbjct: 106 CLGVSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTAL 165
Query: 2161 PFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA 2219
P + D + + ++ GL +++D + V + +P++Y G++CGLCGN +++P
Sbjct: 166 PVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPN 225
Query: 2220 DDLKAVGGKPA--------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPDACGVIS 2270
+D G A W+ G C + CP+ C ++ E + GP CG ++
Sbjct: 226 NDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGPGFCGPLA 284
Query: 2271 -ATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRR 2329
T GP CH VPP +F+GC+LD C G LC A+A+YVAACQAAG + +WR
Sbjct: 285 PGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGVVIEDWRA 344
Query: 2330 PDFCPFQCPAHSHYELCGDSCPGSCPS---LSAPEGCESACREGCVCDAGFVLSGDTCVP 2386
C CP +SHYE+CG CP SCPS L+ P CE C EGC CDAGFVLS D CVP
Sbjct: 345 QVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 404
Query: 2387 VGQ-CGCLHDDRYYPLGQTFYPGPGCDSLCRCREGG-EVSCEPSSCGPHETCR--PSGGS 2442
+ CGC + Y+ G F+ C CRC GG + C P+SCG E C PSG
Sbjct: 405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 464
Query: 2443 LGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQENVAW 2501
GC V + CQA GDPHY T DG RFDF GTC Y+L+ C P G F V N
Sbjct: 465 -GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 523
Query: 2502 GNGRVSVTRVITVQVANFTLRLEQRQW--KVTVNGVDMKLPVVLANGQIRASQHGSDVVI 2559
G+ VS TR +T+Q+ N +L L R W K+ V+GV + LP L + + A G+DVV+
Sbjct: 524 GSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVV 581
Query: 2560 ETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQ----KPNGSQAGNANE 2615
T GL +A+D +VR+ VP Y +CGLCGNYN DP DD + KP G Q G A
Sbjct: 582 TTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQG 641
Query: 2616 FGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSC 2675
G C+ P CP C PE ++ + + CG++S+ GPL+ C
Sbjct: 642 CGE----------CVSKP-CP---------SPCTPEQQESFGGPDACGVISATDGPLAPC 681
Query: 2676 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQ 2735
H LV P + C+ D C G+ LC + YV+ACQAAG Q+ WR FCP++CP
Sbjct: 682 HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPA 741
Query: 2736 NSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYY 2795
+SHYELC D+C + C +LSAP C C EGC CD+GF+ +G CVP+ QCGC H+G YY
Sbjct: 742 HSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYY 801
Query: 2796 EPEQTVLID-NCRQQCTCHVGKVVVCQEHS-CKPGQVCQPSGGILSCVNKDPCHGVTCRP 2853
+ C ++C C G V CQE + C P + C+ G+ +C H C
Sbjct: 802 PLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQAC------HATGC-- 853
Query: 2854 QETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGL 2913
G CL N G HY + DGR +D G+C+YVLA P G
Sbjct: 854 ----------GRCLAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP---KPGD 892
Query: 2914 TPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 2973
F++ + G+ ++ + V G +S+ + + +V V+G ALPV+V GR+
Sbjct: 893 EDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV--GRV 943
Query: 2974 SVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 3033
VT +L GL++ +D + + +++PS + G +CGLCGN + N ++D V PNG+
Sbjct: 944 RVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGS 1003
Query: 3034 LAPSIPIWGGSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTT 3092
A S+ +G +WR PG C + C CP C + YE CG L GPF T
Sbjct: 1004 AASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLR-NPQGPFAT 1062
Query: 3093 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP 3152
C A + P +F+ CV D+C GD+ LC++LA+Y AACQAAGV ++ WR C + CP
Sbjct: 1063 CQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCP 1122
Query: 3153 ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 3212
+SHY +C C SC + + LT C C EGC+CD F+LS C+P+ + CGC
Sbjct: 1123 AHSHYSICTRTCQGSCAALSGLTG---CTTRCFEGCECDDRFLLSQGVCIPVQD-CGCTH 1178
Query: 3213 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 3272
NG Y S CS+ C C G L C A C G VC + ++ C +
Sbjct: 1179 NGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQAAGCPPGRVCEVKAEARN-CW-ATRGL 1234
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE--HRGSQAVSYT 3330
C + T DG R Y LS+ C G + V + H ++AV
Sbjct: 1235 CVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVG-- 1292
Query: 3331 RSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQ-LDSLLHAHLSGADVVVTTTSGLSLA 3389
V + + +TL+ + + V+G+ V LP + L S+ + ++V +G+ +
Sbjct: 1293 -QVHIFFQDGMVTLTPN--KGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVW 1349
Query: 3390 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 3431
+ V + V +AG LCG CGN++ D +D KPA
Sbjct: 1350 LGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA 1391
>gi|239757286 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 1472
Score = 2726 bits (7067), Expect = 0.0
Identities = 1313/1313 (100%), Positives = 1313/1313 (100%)
Query: 19 GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK 78
GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK
Sbjct: 80 GLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSK 139
Query: 79 KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA 138
KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA
Sbjct: 140 KVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQA 199
Query: 139 LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY 198
LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY
Sbjct: 200 LGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPY 259
Query: 199 NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA 258
NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA
Sbjct: 260 NVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLA 319
Query: 259 SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF 318
SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF
Sbjct: 320 SQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLF 379
Query: 319 GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG 378
GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG
Sbjct: 380 GTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVG 439
Query: 379 AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS 438
AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS
Sbjct: 440 AKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLS 499
Query: 439 PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 498
PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM
Sbjct: 500 PVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 559
Query: 499 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 558
VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR
Sbjct: 560 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 619
Query: 559 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 618
LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP
Sbjct: 620 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 679
Query: 619 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 678
ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT
Sbjct: 680 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLT 739
Query: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738
KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP
Sbjct: 740 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 799
Query: 739 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS 798
ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS
Sbjct: 800 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASS 859
Query: 799 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP
Sbjct: 860 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 919
Query: 859 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 918
DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS
Sbjct: 920 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 979
Query: 919 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 978
YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT
Sbjct: 980 YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLT 1039
Query: 979 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1038
VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP
Sbjct: 1040 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1099
Query: 1039 GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1098
GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL
Sbjct: 1100 GCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
Query: 1099 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1158
PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV
Sbjct: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
Query: 1159 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1218
PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE
Sbjct: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
Query: 1219 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1278
GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL
Sbjct: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
Query: 1279 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1331
AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV
Sbjct: 1340 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
Score = 907 bits (2344), Expect = 0.0
Identities = 446/899 (49%), Positives = 557/899 (61%), Gaps = 22/899 (2%)
Query: 2846 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 2905
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 563
Query: 2906 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 2965
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 564 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
Query: 2966 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 3025
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
Query: 3026 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 3085
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 682 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 740
Query: 3086 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 3145
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 800
Query: 3146 GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 3204
C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 801 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 857
Query: 3205 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 3263
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 858 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 915
Query: 3264 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 3323
GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V V NEHRG
Sbjct: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 974
Query: 3324 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTT 3382
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 975 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 1034
Query: 3383 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 3434
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 1035 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1094
Query: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 3494
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 1095 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1153
Query: 3495 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 3554
D C + G G LC A+ATY AACQAAGA + WR + CP CP HSHYE C CP S
Sbjct: 1154 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1213
Query: 3555 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 3614
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H Y+P GQTFYPGPGCDS
Sbjct: 1214 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1273
Query: 3615 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMG 3674
LC C+EGG VSCE SSCGPHE C+PSGGSLGCVAVGS+TCQASGDPHYTTFDG RFDFMG
Sbjct: 1274 LCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMG 1333
Query: 3675 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 3733
TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV
Sbjct: 1334 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
Score = 904 bits (2336), Expect = 0.0
Identities = 445/899 (49%), Positives = 557/899 (61%), Gaps = 22/899 (2%)
Query: 1645 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 1704
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 563
Query: 1705 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 1764
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 564 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
Query: 1765 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 1824
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
Query: 1825 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 1884
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L
Sbjct: 682 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 740
Query: 1885 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 1944
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 800
Query: 1945 GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 2003
C ++CP NS YE+CG CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 801 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 857
Query: 2004 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 2062
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 858 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 915
Query: 2063 GCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2122
GC P CQ GDPHYV+ DG RF+F GTC YLL C G F V V NEHRG
Sbjct: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 974
Query: 2123 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTT 2181
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 975 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 1034
Query: 2182 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 2233
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 1035 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1094
Query: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2293
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 1095 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1153
Query: 2294 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 2353
D C + G G LC A+ATY AACQAAGA + WR + CP CP HSHYE C CP S
Sbjct: 1154 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1213
Query: 2354 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 2413
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H Y+P GQTFYPGPGCDS
Sbjct: 1214 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1273
Query: 2414 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMG 2473
LC C+EGG VSCE SSCGPHE C+PSGGSLGCVAVGS+TCQASGDPHYTTFDGRRFDFMG
Sbjct: 1274 LCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMG 1333
Query: 2474 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 2532
TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV
Sbjct: 1334 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
Score = 754 bits (1948), Expect = 0.0
Identities = 388/914 (42%), Positives = 517/914 (56%), Gaps = 31/914 (3%)
Query: 4047 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 4106
C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+Y + C
Sbjct: 505 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL-C 563
Query: 4107 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 4166
T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V+ + LP
Sbjct: 564 SEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
Query: 4167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 4226
VS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCGN + +P +
Sbjct: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
Query: 4227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSG 4286
D + P+G LAP + SW+ D LC D C+ +CP C + + YEG CG L+
Sbjct: 682 DFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTK- 740
Query: 4287 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 4346
GPF CH + P F + CV D+C+ GG+R LC+ L++Y AC G+ + DWR+
Sbjct: 741 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA 800
Query: 4347 GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG-PCVEGCQCDAGFVLSADRCVPL 4405
C ++CP NS YE+CGP CP SC A P+ C G PCVEGC C GFV S CVP
Sbjct: 801 NCPLSCPANSRYELCGPACPTSCNGAA---APSNCSGRPCVEGCVCLPGFVASGGACVPA 857
Query: 4406 NNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA-SCGLGEVCGLLPSGQH 4464
++ CGC G G E WAD C + C C + C SC GE C + +G
Sbjct: 858 SS-CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSV-QNGLL 915
Query: 4465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 4524
GC P CQ GDPHYV+ DG RFDF GTC YLL C G F V V NEHRG
Sbjct: 916 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENEHRG 974
Query: 4525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTT 4583
SQ VSYTR+V ++ + + +P ++ VD V LPFQ D + G D VV T
Sbjct: 975 SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRT 1034
Query: 4584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 4635
GL++ +D ++ V +VP++YA +LCGLCGN+N DPADDL GG A WQ
Sbjct: 1035 DFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ 1094
Query: 4636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 4695
GCG CP + Q+ + CG+++ GP CH + P + C+
Sbjct: 1095 EETRPGCGATEPGDCPKLDSLVAQQ-LQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1153
Query: 4696 LDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVS 4755
D C + G G LC A+ATY AACQAAGA + WR + CPL CP HSHYE C CP+S
Sbjct: 1154 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1213
Query: 4756 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECER 4815
C L P GC S C EGCVCD GF LSG++C+P+ CGC+H G Y+P G+ FYPGP C+
Sbjct: 1214 CGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDS 1273
Query: 4816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLH 4875
C C GG V+C E ++CGPHE C+ G C A G C A+G HY T DGR +D
Sbjct: 1274 LCHCQEGGLVSC-ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFM 1332
Query: 4876 GSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQ-QVTV 4929
G+C YVLAQ C +PG F+++ E A G+ + + V VA + L Q Q +VTV
Sbjct: 1333 GTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTV 1392
Query: 4930 --DGEAVALPVAVG 4941
DGE A + VG
Sbjct: 1393 RADGEQGARGLWVG 1406
Score = 748 bits (1930), Expect = 0.0
Identities = 387/915 (42%), Positives = 492/915 (53%), Gaps = 55/915 (6%)
Query: 834 TCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS 893
+C Q C AG+RC V G GC + C+ GDPHY +FDGRR+D MGTC+Y +V
Sbjct: 504 SCEGMQ-CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL 562
Query: 894 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953
C ++ LPAF V +NEHRGS+ VSY V V A V++ R G VLVD+ LP
Sbjct: 563 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 954 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013
++G+++V++ G AVV FGL VTYDW+ ++ +P+ + + +CGLCGN+NGDPADD
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 1014 LALRGGGQAANALAFGNSWQEET-----RPGCGATEPGDCPKLDSLVAQQLQSKNECGIL 1068
G A +A+ F +SW+ + GC +CP AQ + CG+L
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC----QNNCPACTPGQAQHYEGDRLCGML 738
Query: 1069 ADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRS 1128
GPF CH LDP+ + CVYD C++ G+ LC L+ YA AC G +V WRS
Sbjct: 739 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 798
Query: 1129 EELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC-GSECHEGCVCDEGFALSGESCLPLA 1187
CPLSCP +S YE C CP SC P C G C EGCVC GF SG +C+P +
Sbjct: 799 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPAS 858
Query: 1188 SCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGG-LVSC-ESSSCGPHEACQPSGGSLGCV 1245
SCGC QG PGQ + C C C V+C + SC E C G LGC
Sbjct: 859 SCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCY 918
Query: 1246 AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRV 1305
TCQ SGDPHY +FDGRRFDFMGTC Y+L +CG L F VL EN G+ V
Sbjct: 919 PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 978
Query: 1306 SVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
S TR + V+ + + + +V V+ V LP A+GQ++ + G D V+ TDFGL
Sbjct: 979 SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 1038
Query: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-EEVV 1423
V YD V VP +Y + +CGLCGN+NGDP DD G QA NA FGNSW EE
Sbjct: 1039 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1098
Query: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
P P CP K + ++ Q + CG+L+ P GP CH +DPQG
Sbjct: 1099 PGCGATEPGDCP----------KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGA 1148
Query: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
++DC++D CL G LC + Y +ACQAAG V PWR+E CP+ CPP+SHYE C+
Sbjct: 1149 VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY 1208
Query: 1544 TCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLI- 1602
C L C L P C C EGC CD GF +G++C+P+ CGC H G Y+ P QT
Sbjct: 1209 GCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1268
Query: 1603 DNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQ 1662
C C C G + C+ SC P + CQPSGG L CV
Sbjct: 1269 PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG------------------- 1309
Query: 1663 GVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
+TC GDPHY +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 1310 -------SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENV 1359
Query: 1723 NRGNPAVSYVRVVTV 1737
GN VS RV+TV
Sbjct: 1360 AWGNGRVSVTRVITV 1374
Score = 685 bits (1767), Expect = 0.0
Identities = 369/912 (40%), Positives = 469/912 (51%), Gaps = 58/912 (6%)
Query: 3244 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 3303
C C G+ C ++ G+ GC STA C+A GDPHY T DG R+D GTC Y + C
Sbjct: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 3304 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPF 3363
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 3364 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADD 3422
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 3423 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 3473
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
Query: 3474 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDF 3533
DGP A CH + P + + C+ D C V G LC ++ Y AC G + +WR P
Sbjct: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
Query: 3534 CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 3592
CP CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
Query: 3593 CLHDDRYYPLGQTFYPGPGCDSLCRCREGG-EVSC-EPSSCGPHETCRPSGGSLGCVAVG 3650
C GQ + C C C +V+C + SC E C G LGC
Sbjct: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
Query: 3651 STTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 3710
TCQ SGDPHY +FDG RFDFMGTC Y+L +CG L F VL EN G+ VS T
Sbjct: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
Query: 3711 RVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 3769
R + V+ + + + +V V+ V LP A+GQ++ + G D V+ TDFGL V
Sbjct: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
Query: 3770 YDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-EEVVPDS 3828
YD V VP +Y + +CGLCGN+NGDP DD G QA NA FGNSW EE P
Sbjct: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC 1101
Query: 3829 PCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 3888
P CP K + ++ Q + CG+L+ P GP CH +DPQG ++D
Sbjct: 1102 GATEPGDCP----------KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1151
Query: 3889 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCS 3948
C++D CL G LC + Y +ACQAAG V PWR+E CP+ CP +SHYE C+ C
Sbjct: 1152 CVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCP 1211
Query: 3949 LGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLI-DNC 4007
L C L P C C EGC CD GF +G++C+P+ CGC H G Y+ P QT C
Sbjct: 1212 LSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGC 1271
Query: 4008 RQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 4067
C C G +V C+ SC P + CQPSGG L CV
Sbjct: 1272 DSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG---------------------- 1309
Query: 4068 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG 4127
+TC GDPHY +FDGR+FDF GTC YVLA T C + GL F V +N G
Sbjct: 1310 ----SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENVAWG 1362
Query: 4128 NPAVSYVRVVTV 4139
N VS RV+TV
Sbjct: 1363 NGRVSVTRVITV 1374
Score = 683 bits (1762), Expect = 0.0
Identities = 368/912 (40%), Positives = 470/912 (51%), Gaps = 58/912 (6%)
Query: 2043 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPC 2102
C C G+ C ++ G+ GC STA C+A GDPHY T DG R++ GTC Y + C
Sbjct: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 2103 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPF 2162
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 2163 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADD 2221
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 2222 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 2272
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
Query: 2273 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDF 2332
DGP A CH + P + + C+ D C V G LC ++ Y AC G + +WR P
Sbjct: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
Query: 2333 CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 2391
CP CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
Query: 2392 CLHDDRYYPLGQTFYPGPGCDSLCRCREGG-EVSC-EPSSCGPHETCRPSGGSLGCVAVG 2449
C GQ + C C C +V+C + SC E C G LGC
Sbjct: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
Query: 2450 STTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 2509
TCQ SGDPHY +FDGRRFDFMGTC Y+L +CG L F VL EN G+ VS T
Sbjct: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
Query: 2510 RVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 2568
R + V+ + + + +V V+ V LP A+GQ++ + G D V+ TDFGL V
Sbjct: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
Query: 2569 YDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-EEVVPDS 2627
YD V VP +Y + +CGLCGN+NGDP DD G QA NA FGNSW EE P
Sbjct: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC 1101
Query: 2628 PCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 2687
P CP + + ++ Q + CG+L+ P GP CH +DPQG ++D
Sbjct: 1102 GATEPGDCP----------KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1151
Query: 2688 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCS 2747
C++D CL G LC + Y +ACQAAG V PWR+E CP+ CP +SHYE C+ C
Sbjct: 1152 CVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCP 1211
Query: 2748 LGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLI-DNC 2806
L C L P C C EGC CD GF +G++C+P+ CGC H G Y+ P QT C
Sbjct: 1212 LSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGC 1271
Query: 2807 RQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVC 2866
C C G +V C+ SC P + CQPSGG L CV
Sbjct: 1272 DSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVG---------------------- 1309
Query: 2867 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG 2926
+TC GDPHY +FDGR+FDF GTC YVLA T C + GL F V +N G
Sbjct: 1310 ----SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENVAWG 1362
Query: 2927 NPAVSYVRVVTV 2938
N VS RV+TV
Sbjct: 1363 NGRVSVTRVITV 1374
Score = 682 bits (1760), Expect = 0.0
Identities = 376/940 (40%), Positives = 500/940 (53%), Gaps = 50/940 (5%)
Query: 2422 EVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQ 2481
E SCE C + C+ GG GCVA + C+A GDPHYTTFDGRR+D MGTC Y + +
Sbjct: 502 EPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE 561
Query: 2482 TCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 2540
C L F+V +N G+ RVS ++TV+ + ++ L + + V V+ +LP
Sbjct: 562 LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
Query: 2541 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKD 2600
V L+ G++R Q G V+E FGL V YD + +++P + +CGLCGNYNGDP D
Sbjct: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
Query: 2601 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEE 2660
DF P+G+ A +A EF +SW+ + D L C G + P+ C P + Y+ +
Sbjct: 682 DFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYEGDR 733
Query: 2661 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQV 2720
CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G V
Sbjct: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
Query: 2721 EPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQA 2779
WR+ CP+ CP NS YELC C C+ +AP C C EGC C GF+ +G A
Sbjct: 794 GDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGA 853
Query: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDN-CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGIL 2838
CVP CGC G P Q V D C+++CTC+ + +C+ Q C P+G
Sbjct: 854 CVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCN----GATHQVTCRDKQSC-PAG--- 905
Query: 2839 SCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNY 2898
E C Q G C P+ TC GDPHY SFDGR+FDF GTC Y
Sbjct: 906 ----------------ERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTY 949
Query: 2899 VLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVN 2958
+L G G L F V +N++RG+ VSY R V V A G +++ ++ G+V V+
Sbjct: 950 LL--VGSCG-QNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVD 1006
Query: 2959 GVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 3018
VL LP ADG++ V + A++ DFGL V+YDWN RV +PSSY A+CGLCGN
Sbjct: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
Query: 3019 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGF 3078
+ +P +D G A + +G SW+ P C G CP +Q +
Sbjct: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNE 1125
Query: 3079 CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVI 3138
CG LA GPF CH+ + P+ + CV D C+ G LC ALA+Y AACQAAG +
Sbjct: 1126 CGILA-DPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATV 1184
Query: 3139 EDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA 3198
WR++ C ++CP +SHYE C CP SC L P C C EGC CD GF LS
Sbjct: 1185 HPWRSEELCPLSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSECHEGCVCDEGFALSG 1241
Query: 3199 DRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLL 3258
+ C+PL + CGC GTYH G F+ C C C GG + C +SCG E C
Sbjct: 1242 ESCLPLAS-CGCVHQGTYHPPGQTFYPGPGCDSLCHC-QEGGLVSCESSSCGPHEAC--Q 1297
Query: 3259 PS-GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTV 3317
PS G GC V ++ CQA GDPHY T DG RFDF GTC Y+L+ C P G F V
Sbjct: 1298 PSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQ 1356
Query: 3318 ANEHRGSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDG 3356
N G+ VS TR +T+Q+ N +L L R W ++ DG
Sbjct: 1357 ENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRADG 1396
Score = 679 bits (1751), Expect = 0.0
Identities = 374/940 (39%), Positives = 499/940 (53%), Gaps = 50/940 (5%)
Query: 3623 EVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQ 3682
E SCE C + C+ GG GCVA + C+A GDPHYTTFDG R+D MGTC Y + +
Sbjct: 502 EPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE 561
Query: 3683 TCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLP 3741
C L F+V +N G+ RVS ++TV+ + ++ L + + V V+ +LP
Sbjct: 562 LCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 621
Query: 3742 VVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKD 3801
V L+ G++R Q G V+E FGL V YD + +++P + +CGLCGNYNGDP D
Sbjct: 622 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 681
Query: 3802 DFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEE 3861
DF P+G+ A +A EF +SW+ + D L C G P+ C P + Y+ +
Sbjct: 682 DFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYEGDR 733
Query: 3862 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHV 3921
CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G V
Sbjct: 734 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 793
Query: 3922 EPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQA 3980
WR+ CP+ CP NS YELC C C+ +AP C C EGC C GF+ +G A
Sbjct: 794 GDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGA 853
Query: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDN-CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGIL 4039
CVP CGC G+ P Q V D C+++CTC+ + +C+ Q C P+G
Sbjct: 854 CVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCN----GATHQVTCRDKQSC-PAG--- 905
Query: 4040 SCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNY 4099
E C Q G C P+ TC GDPHY SFDGR+FDF GTC Y
Sbjct: 906 ----------------ERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTY 949
Query: 4100 VLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVN 4159
+L G G L F V +N++RG+ VSY R V V A G +++ ++ G+V V+
Sbjct: 950 LL--VGSCG-QNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVD 1006
Query: 4160 GVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGN 4219
VL LP ADG++ V + A++ DFGL V+YDWN RV +PSSY A+CGLCGN
Sbjct: 1007 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1066
Query: 4220 MDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGF 4279
+ +P +D G A + +G SW+ P C G CP +Q +
Sbjct: 1067 FNGDPADDLALRGGGQAANALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNE 1125
Query: 4280 CGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVI 4339
CG L+ GPF CH+ + P+ + CV D C+ G LC ALA+Y AACQAAG +
Sbjct: 1126 CGILAD-PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATV 1184
Query: 4340 EDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA 4399
WR++ C ++CP +SHYE C CP SC L P C C EGC CD GF LS
Sbjct: 1185 HPWRSEELCPLSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSECHEGCVCDEGFALSG 1241
Query: 4400 DRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLL 4459
+ C+PL + CGC GTYH G F+ C C C GG + C +SCG E C
Sbjct: 1242 ESCLPLAS-CGCVHQGTYHPPGQTFYPGPGCDSLCHC-QEGGLVSCESSSCGPHEAC--Q 1297
Query: 4460 PS-GQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTV 4518
PS G GC V ++ CQA GDPHY T DG RFDF GTC Y+L+ C P G F V
Sbjct: 1298 PSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQ 1356
Query: 4519 ANEHRGSQAVSYTRSVTLQIYNHSLTLSAR-WPRKLQVDG 4557
N G+ VS TR +T+Q+ N +L L R W ++ DG
Sbjct: 1357 ENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVRADG 1396
Score = 585 bits (1508), Expect = e-166
Identities = 320/862 (37%), Positives = 433/862 (50%), Gaps = 37/862 (4%)
Query: 4445 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 4504
C C G+ C ++ G+ GC STA C+A GDPHY T DG R+D GTC Y + C
Sbjct: 505 CEGMQCAAGQRCQVV-GGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 4505 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPF 4564
F+V NEHRGS+ VSY VT++ Y+HS++L+ + VD LP
Sbjct: 564 SEDDT-LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 622
Query: 4565 QL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 4623
L + L + SG VV GL + +D D + L +PA + +CGLCGNYN DPADD
Sbjct: 623 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 682
Query: 4624 LKAVGGKPA--------GWQVG-GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 4674
G A W++ G C + CP+ CTP Q + + G CG+++
Sbjct: 683 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKL 741
Query: 4675 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF 4734
DGP A CH + P + + C+ D C V G LC ++ Y AC G +G+WR P
Sbjct: 742 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 801
Query: 4735 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESA-CREGCVCDAGFVLSGDTCVPVGQCG 4793
CPL CPA+S YELCG +CP SC +AP C C EGCVC GFV SG CVP CG
Sbjct: 802 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 861
Query: 4794 CLHDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQEGAACGPHEECRLEDGVQACHATG 4852
C G G+ + C+RRC C H VTC++ +C E C +++G+ C+
Sbjct: 862 CTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDR 921
Query: 4853 CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----L 4907
G C +G HY++ DGR +D G+C+Y+L C F +++E G
Sbjct: 922 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYT 981
Query: 4908 QRLLVTVAGQVVSLAQGQ--QVTVDGEAVALP--VAVGRVRVTAEGRNMVLQTTKGLRLL 4963
+ + V G V++ + QV VD LP A G+V+V +GR+ V++T GL +
Sbjct: 982 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 1041
Query: 4964 FDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKG 5023
+D +A + +PS + LCGLCGNFNG+ +DD L G A++ FG +W+ + G
Sbjct: 1042 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE-TRPG 1100
Query: 5024 CGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQ 5083
CG P CP + +S CG L +P+GPF C + L P R CVYD C
Sbjct: 1101 CG-ATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL 1159
Query: 5084 KGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSG 5143
G LC +LA Y AACQAAG V PWR++ CPL CP HSHY C+ C SC L
Sbjct: 1160 PGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV 1219
Query: 5144 LTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS-DCSERCSCSS 5202
GC + C EGC CD+ F LS C+P+ CGC H G Y P + C C C
Sbjct: 1220 PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQE 1279
Query: 5203 SSGLTCQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYEL 5261
++C+++ C P C+ + C A C S + TTFDG R VY L
Sbjct: 1280 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1339
Query: 5262 SSRC---PG------LQNTIPW 5274
+ C PG LQ + W
Sbjct: 1340 AQTCGTRPGLHRFAVLQENVAW 1361
Score = 322 bits (825), Expect = 6e-87
Identities = 195/581 (33%), Positives = 281/581 (48%), Gaps = 39/581 (6%)
Query: 4829 EGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHP 4888
EG C + C++ G C A C A G HY T DGR YD+ G+CSY + ++C
Sbjct: 506 EGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSE 565
Query: 4889 KPGDEDFSIVLEKNAAGDLQRL---LVTVAG--QVVSLAQGQQ--VTVDGEAVALPVAV- 4940
FS+ + G + LVTV VSL +G+ V VD + LPV++
Sbjct: 566 DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLS 625
Query: 4941 -GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVL 4999
GR+RV G V++ GL + +D D L +S+P+ F+ ++CGLCGN+NG+ +DDF+
Sbjct: 626 EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 685
Query: 5000 PNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGP 5059
P+G+ A F ++W+ C +GC CP C + YE + CG L GP
Sbjct: 686 PDGALAPDAVEFASSWKLDDGDYLCEDGC-QNNCPACTPGQAQHYEGDRLCGMLTKLDGP 744
Query: 5060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL 5119
FA C L P + QCVYDLC G++ LCR L+AY AC G++V WR+ + CPL
Sbjct: 745 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 804
Query: 5120 HCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQDCGCTH 5178
CPA+S Y +C C SC + + C+ R C EGC C F+ S G C+P CGCT
Sbjct: 805 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 864
Query: 5179 NGRYLPVNSSLLTSD-CSERCSCSSSSG-LTCQ-AAGCPPGRVCEVKAEARNCWATR-GL 5234
G L + + C RC+C+ ++ +TC+ CP G C V+ C+ R G
Sbjct: 865 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 924
Query: 5235 CVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQV 5294
C S + +FDG R Y L C G +P +RV+ E + H ++ V
Sbjct: 925 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSC-GQNAALPAFRVLVENE--HRGSQTVSYT 981
Query: 5295 HIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTP----DGSL---------LVR 5341
+ +GV V +R + P + L + P DG + +VR
Sbjct: 982 RAVRVEA-------RGVKV-AVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 1033
Query: 5342 QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 5382
G+ V N +V V + +A LCG CGNF+GD +D
Sbjct: 1034 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1074
Score = 42.7 bits (99), Expect = 0.010
Identities = 49/190 (25%), Positives = 82/190 (43%), Gaps = 23/190 (12%)
Query: 5207 TCQAAGCPPGRVCEVKAEARNCWA-TRGLCVLSVGANLTTFDGARGATTSPGVYELSSRC 5265
+C+ C G+ C+V C A + +C + TTFDG R Y + C
Sbjct: 504 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 563
Query: 5266 PGLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKG--VWVNGLRVDLPA 5322
+T+P + V A+ + + + VG V + V+LT + V V+ R LP
Sbjct: 564 SE-DDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP- 621
Query: 5323 EKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAGKLCGACG 5373
VS+S +G L V Q G+ V + ++A+ + ++CG CG
Sbjct: 622 -----VSLS---EGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 673
Query: 5374 NFDGDQTNDW 5383
N++GD +D+
Sbjct: 674 NYNGDPADDF 683
>gi|239757284 PREDICTED: similar to Fc fragment of IgG binding protein
[Homo sapiens]
Length = 593
Score = 1165 bits (3014), Expect = 0.0
Identities = 537/573 (93%), Positives = 538/573 (93%), Gaps = 34/573 (5%)
Query: 1336 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 1395
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG
Sbjct: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
Query: 1396 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 1455
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY
Sbjct: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
Query: 1456 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 1515
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
Query: 1516 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 1575
GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN
Sbjct: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
Query: 1576 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGG 1635
GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK +VCQEHSCKPGQVCQPSGG
Sbjct: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 1636 ILSCVTK----------------------------------DPCHGVTCRPQETCKEQGG 1661
ILSCVTK DPCHGVTCRPQETCKEQGG
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 1662 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 1721
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 1722 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 1781
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA
Sbjct: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
Query: 1782 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 1841
LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG
Sbjct: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
Query: 1842 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 1874
GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG
Sbjct: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
Score = 1138 bits (2943), Expect = 0.0
Identities = 527/573 (91%), Positives = 527/573 (91%), Gaps = 34/573 (5%)
Query: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ MCGLCGNYNG
Sbjct: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
Query: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP CPPGS CIPS KCPPELEKKY
Sbjct: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
Query: 3858 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 3917
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
Query: 3918 GGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 3977
GGHVEPWR ETFCPMECP NSHYELCADTCSLGCSALSAP QC DGCAEGCQCDSGFLYN
Sbjct: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
Query: 3978 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGG 4037
GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCH GKVVVCQEHSCKPGQVCQPSGG
Sbjct: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 4038 ILSCVTK----------------------------------DPCHGVTCRPQETCKEQGG 4063
ILSCVTK DPCHGVTCRPQETCKEQGG
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 4064 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 4123
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 4124 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKA 4183
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV QGASKA
Sbjct: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
Query: 4184 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 4243
LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG
Sbjct: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
Query: 4244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 4276
GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG
Sbjct: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
Score = 1134 bits (2934), Expect = 0.0
Identities = 525/573 (91%), Positives = 526/573 (91%), Gaps = 34/573 (5%)
Query: 2537 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 2596
MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ MCGLCGNYNG
Sbjct: 1 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG 60
Query: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656
DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP CPPGSE CIPS +CPPELEKKY
Sbjct: 61 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY 120
Query: 2657 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 2716
QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA
Sbjct: 121 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 180
Query: 2717 GGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 2776
GG VEPWR ETFCPMECP NSHYELCADTCSLGCSALSAP QC DGCAEGCQCDSGFLYN
Sbjct: 181 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN 240
Query: 2777 GQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGG 2836
GQACVPIQQCGCYHNG YYEPEQTVLIDNCRQQCTCH GKVVVCQEHSCKPGQVCQPSGG
Sbjct: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 2837 ILSCVNK----------------------------------DPCHGVTCRPQETCKEQGG 2862
ILSCV K DPCHGVTCRPQETCKEQGG
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 2863 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 2922
QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 2923 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 2982
QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA
Sbjct: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
Query: 2983 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 3042
LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG
Sbjct: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
Query: 3043 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 3075
GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG
Sbjct: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
Score = 388 bits (996), Expect = e-107
Identities = 217/572 (37%), Positives = 285/572 (49%), Gaps = 78/572 (13%)
Query: 951 LPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDP 1010
LP A+GQ++ + G D V+ TDFGL V YD V VP +Y + +CGLCGN+NGDP
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 1011 ADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP----------KLDSLVAQQLQ 1060
DD G QA NA FGNSW EE P P CP K + ++ Q
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSW-EEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
Query: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG 1120
+ CG+L+ P GP CH +DPQG ++DC++D CL G LC + Y +ACQAAG
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 1121 ATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
V PWR+E CP+ CPP+SHYE C+ C L C L P C C EGC CD GF +G
Sbjct: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG 241
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
++C+P+ CGC H G Y+ P QT C C C G +V C+ SC P + CQPSGG
Sbjct: 242 QACVPIQQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 1241 SLGCVAV-------------------------------------------GSSTCQASGD 1257
L CV TC+ G
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGG 360
Query: 1258 -----PHYT------------TFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQEN 1297
P+Y +FDGR+FDF GTC YVLA T C + GL F V +N
Sbjct: 361 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 420
Query: 1298 VAWGNGRVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDV 1356
GN VS RV+TV + + + + KV VNGV LPV +A+G+I +Q S
Sbjct: 421 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 480
Query: 1357 VIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG 1416
++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P +D PNG+ A + +G
Sbjct: 481 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 540
Query: 1417 NSWEEVVPDSPCLPPT--PCPPGSEDCIPSHK 1446
SW D C CP ED + ++
Sbjct: 541 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYE 572
Score = 347 bits (890), Expect = 2e-94
Identities = 206/558 (36%), Positives = 275/558 (49%), Gaps = 94/558 (16%)
Query: 2168 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGG 2227
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
Query: 2228 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 2267
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
Query: 2268 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREW 2327
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
Query: 2328 RRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 2387
R FCP +CP +SHYELC D+C C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
Query: 2388 GQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCV- 2446
QCGC H+ YY QT C C C G V C+ SC P + C+PSGG L CV
Sbjct: 248 QQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVT 306
Query: 2447 -----AVGST-------------------------------------TCQASGD-----P 2459
++ T TC+ G P
Sbjct: 307 KVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLP 366
Query: 2460 HYT------------TFDGRRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENVAWGNG 2504
+Y +FDGR+FDF GTC YVLA T C + GL F V +N GN
Sbjct: 367 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNP 426
Query: 2505 RVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF 2563
VS RV+TV + + + + KV VNGV LPV +A+G+I +Q S ++ DF
Sbjct: 427 AVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF 486
Query: 2564 GLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEV 2623
GL+V+YD + V VT+P +Y+ +CGLCGN + +P +D PNG+ A + +G SW
Sbjct: 487 GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP 546
Query: 2624 VPDSPCLPP-----PTCP 2636
D C PTCP
Sbjct: 547 GWDPLCWDECRGSCPTCP 564
Score = 345 bits (885), Expect = 7e-94
Identities = 205/558 (36%), Positives = 274/558 (49%), Gaps = 94/558 (16%)
Query: 3369 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGG 3428
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
Query: 3429 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 3468
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
Query: 3469 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREW 3528
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
Query: 3529 RRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 3588
R FCP +CP +SHYELC D+C C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
Query: 3589 GQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCV- 3647
QCGC H+ YY QT C C C G V C+ SC P + C+PSGG L CV
Sbjct: 248 QQCGCYHNGVYYEPEQTVLI-DNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGGILSCVT 306
Query: 3648 -----AVGST-------------------------------------TCQASGD-----P 3660
++ T TC+ G P
Sbjct: 307 KVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVCLP 366
Query: 3661 HYT------------TFDGHRFDFMGTCVYVLAQT-CG--TRPGLHRFAVLQENVAWGNG 3705
+Y +FDG +FDF GTC YVLA T C + GL F V +N GN
Sbjct: 367 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNP 426
Query: 3706 RVSVTRVITVQVANFTLRLEQRQ-WKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF 3764
VS RV+TV + + + + KV VNGV LPV +A+G+I +Q S ++ DF
Sbjct: 427 AVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF 486
Query: 3765 GLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEV 3824
GL+V+YD + V VT+P +Y+ +CGLCGN + +P +D PNG+ A + +G SW
Sbjct: 487 GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP 546
Query: 3825 VPDSPCLPP-----PTCP 3837
D C PTCP
Sbjct: 547 GWDPLCWDECRGSCPTCP 564
Score = 331 bits (848), Expect = 1e-89
Identities = 209/598 (34%), Positives = 286/598 (47%), Gaps = 83/598 (13%)
Query: 558 RLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGD 617
+LPV L+ G++R Q G V+E FGL V YD + +++P + Q+CGLCGNYNGD
Sbjct: 2 KLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 61
Query: 618 PADDFLTPDGALAPDAVEFASSWK--LDDGDYL----CEDGCQNNCPA--CTPGQAQHYE 669
P DDF P+G+ A +A EF +SW+ + D L C G ++ P+ C P + Y+
Sbjct: 62 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 121
Query: 670 GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELG 729
+ CG+L+ GP + CH +DP+ L+ C++DLC+ GG LC + AY AC G
Sbjct: 122 KEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG 181
Query: 730 ISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGC--------- 780
V WR+ CP+ CP NS YELC C C+ +AP C C EGC
Sbjct: 182 GHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG-CAEGCQCDSGFLYN 240
Query: 781 --VCLP----GFVASGGACVPASS---------CGC------TFQGLQLAPGQ------- 812
C+P G +G P + C C Q PGQ
Sbjct: 241 GQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSGG 300
Query: 813 ------EVWADELCQRRCTCNGAT--------------------HQVTCRDKQSCPAGER 846
+V L Q GA H VTCR + E
Sbjct: 301 ILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQ------ET 354
Query: 847 CSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLV--GSCGQNA-ALPAF 903
C Q G C P+ TC GDPHY SFDGR+FDF GTC Y+L G G + L F
Sbjct: 355 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 414
Query: 904 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
V +N++RG+ VSY R V V A G +++ ++ G+V V+ VL LP ADG++ V
Sbjct: 415 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 474
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAA 1023
+ A++ DFGL V+YDWN RV +PSSY A+CGLCGN + +P +D G A
Sbjct: 475 QGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAP 534
Query: 1024 NALAFGNSWQEE-TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHS 1080
+ +G SW+ P C G CP +Q + +E G L+D K C++
Sbjct: 535 SIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGLDE-GSLSDHKDKIFMCYT 591
Score = 326 bits (835), Expect = 4e-88
Identities = 199/583 (34%), Positives = 290/583 (49%), Gaps = 91/583 (15%)
Query: 4165 LPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 4224
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 4225 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 4274
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
Query: 4275 EGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQA 4334
+ FCG LSS TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 4335 AGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 4394
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
Query: 4395 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 4454
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
Query: 4455 VC----------------------------GLLPSGQ--------------HG--CQPVS 4470
VC +L +GQ HG C+P
Sbjct: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
Query: 4471 T---------------AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP-CHG-PPLGAEN 4513
T A C WGDPHY + DG +FDFQGTC Y+L+ C G G
Sbjct: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
Query: 4514 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHA 4572
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV ALP + D +
Sbjct: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
Query: 4573 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA 4632
+ ++ GL +++D + V + +P++Y ++CGLCGN +++P +D G A
Sbjct: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
Query: 4633 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 4666
W+ G C + CP+ C ++ E + G D
Sbjct: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
Score = 324 bits (831), Expect = 1e-87
Identities = 193/569 (33%), Positives = 274/569 (48%), Gaps = 101/569 (17%)
Query: 4570 LHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGG 4629
+ A G+DVV+ T GL +A+D +VR+ VP Y +CGLCGNYN DP DD +
Sbjct: 12 IRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQ---- 67
Query: 4630 KPAGWQVGGAQGCGECVSK-----------PCPS---------PCTPEQQESFGGPDACG 4669
KP G Q G A G + PCP C PE ++ + + CG
Sbjct: 68 KPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCG 127
Query: 4670 VISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEW 4729
++S+ GPL+ CH LV P + C+ D C G+ LC + YV+ACQAAG + W
Sbjct: 128 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPW 187
Query: 4730 RRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPV 4789
R FCP++CP +SHYELC D+C + C +LSAP C+ C EGC CD+GF+ +G CVP+
Sbjct: 188 RTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPI 247
Query: 4790 GQCGCLHDGRYY-PLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGV--- 4845
QCGC H+G YY P V C ++C C G V CQE +C P + C+ G+
Sbjct: 248 QQCGCYHNGVYYEPEQTVLI--DNCRQQCTCHAGKVVVCQE-HSCKPGQVCQPSGGILSC 304
Query: 4846 -------------------------------------QACHATGC------------GRC 4856
CH C G C
Sbjct: 305 VTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQETCKEQGGQGVC 364
Query: 4857 LAN--------GGIHYITLDGRVYDLHGSCSYVLAQVCHP---KPGDEDFSIVLEKNAAG 4905
L N G HY + DGR +D G+C+YVLA P G F++ + G
Sbjct: 365 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG 424
Query: 4906 D-----LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVAV--GRVRVTAEGRNMVLQT 4956
+ ++ + V G +S+ + + +V V+G ALPV+V GR+ VT +L
Sbjct: 425 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 484
Query: 4957 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 5016
GL++ +D + + +++PS + G +CGLCGN + N ++D V PNG+ A S+ +G +WR
Sbjct: 485 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 544
Query: 5017 APGSSKGCGEGCGPQGCPVCLAEETAPYE 5045
APG C + C CP C + YE
Sbjct: 545 APGWDPLCWDEC-RGSCPTCPEDRLEQYE 572
Score = 323 bits (829), Expect = 2e-87
Identities = 197/583 (33%), Positives = 289/583 (49%), Gaps = 91/583 (15%)
Query: 2964 LPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 3023
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 3024 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 3073
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
Query: 3074 EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQA 3133
+ FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 3134 AGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 3193
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
Query: 3194 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 3253
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
Query: 3254 VC----------------------------GLLPSGQ--------------HG--CQPVS 3269
VC +L +GQ HG C+P
Sbjct: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
Query: 3270 T---------------AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP-CHG-PPLGAEN 3312
T A C WGDPHY + DG +FDFQGTC Y+L+ C G G
Sbjct: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
Query: 3313 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHA 3371
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV LP + D +
Sbjct: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
Query: 3372 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 3431
+ ++ GL +++D + V + +P++Y G++CGLCGN +++P +D G A
Sbjct: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
Query: 3432 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 3465
W+ G C + CP+ C ++ E + G D
Sbjct: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
Score = 322 bits (825), Expect = 6e-87
Identities = 196/583 (33%), Positives = 289/583 (49%), Gaps = 91/583 (15%)
Query: 1763 LPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNP 1822
LPV +A+G+I +Q S ++ DFGL+V+YD + V VT+P +Y+ +CGLCGN + +P
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 1823 NNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT----------CPEDRLEQY 1872
+D PNG+ A + +G SW D C CP CP + ++Y
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT--PCPPGSEDCIPSHKCPPELEKKY 120
Query: 1873 EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQA 1932
+ FCG L+ TG P ++CH V P+ K C+ D+C+GGG+ ILC + +YV+ACQA
Sbjct: 121 QKEEFCGLLSSPTG-PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 1933 AGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG 1992
AG +E WR + C + CP NSHYE+C C C + L+ P C+ C EGCQCD+G
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC---SALSAPPQCQDGCAEGCQCDSG 236
Query: 1993 FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGE 2052
F+ + CVP+ CGC+ NG Y+E D C Q C C G +VC SC G+
Sbjct: 237 FLYNGQACVPIQQ-CGCYHNGVYYEPEQTVLID-NCRQQCTC-HAGKVVVCQEHSCKPGQ 293
Query: 2053 VC----------------------------GLLPSGQ--------------HG--CQPVS 2068
VC +L +GQ HG C+P
Sbjct: 294 VCQPSGGILSCVTKVTLRSLAQTGVDVEGAAILYNGQPLKVLLPLLSPDPCHGVTCRPQE 353
Query: 2069 T---------------AECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP-CHG-PPLGAEN 2111
T A C WGDPHY + DG +F+FQGTC Y+L+ C G G
Sbjct: 354 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 413
Query: 2112 FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHA 2170
FTVT N++RG+ AVSY R VT+ ++++ K++V+GV LP + D +
Sbjct: 414 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 473
Query: 2171 HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA 2230
+ ++ GL +++D + V + +P++Y G++CGLCGN +++P +D G A
Sbjct: 474 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 533
Query: 2231 --------GWQVGGAQG-CGECVSKPCPSPCTPEQQESFGGPD 2264
W+ G C + CP+ C ++ E + G D
Sbjct: 534 PSIPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGLD 575
Score = 254 bits (649), Expect = 2e-66
Identities = 114/305 (37%), Positives = 173/305 (56%), Gaps = 15/305 (4%)
Query: 4936 LPVAV--GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNW 4993
LPV + G++R + G ++V++T GLR+ +D ++ +++P + ++CGLCGN+NG+
Sbjct: 3 LPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDP 62
Query: 4994 SDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPV----CLAEETAP------ 5043
DDF PNGS A + FG +W C P CP C+ P
Sbjct: 63 KDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKCPPELEKK 119
Query: 5044 YESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQA 5103
Y+ E CG L +P GP ++C ++ P + C++DLC G+ + LC ++ AY +ACQA
Sbjct: 120 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 179
Query: 5104 AGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL 5163
AG V+PWRT++FCP+ CP +SHY +C TC C+ALS C C EGC+CD FL
Sbjct: 180 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 239
Query: 5164 SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKA 5223
+ C+P+Q CGC HNG Y ++L +C ++C+C + + CQ C PG+VC+
Sbjct: 240 NGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKVVVCQEHSCKPGQVCQPSG 299
Query: 5224 EARNC 5228
+C
Sbjct: 300 GILSC 304
Score = 187 bits (474), Expect = 3e-46
Identities = 93/238 (39%), Positives = 142/238 (59%), Gaps = 5/238 (2%)
Query: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
+LSP C G+ C + C+ GG+ C+ A C GDPHY +FDGR++D GTC+
Sbjct: 338 LLSP--DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 395
Query: 496 YTMVEL-CSEDDT--LPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLV 552
Y + C T L F+V KN++RG+ VSYV +VTV A ++S+ + E+G V V
Sbjct: 396 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 455
Query: 553 DNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCG 612
+ + LPVS+++GR+ V Q +A++ FGL V+YDW+ ++ ++LP+ + VCGLCG
Sbjct: 456 NGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCG 515
Query: 613 NYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEG 670
N + +P +D + P+G LAP + SW+ D LC D C+ +CP C + + YEG
Sbjct: 516 NMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 573
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 878 bits (2269), Expect = 0.0
Identities = 565/1787 (31%), Positives = 809/1787 (45%), Gaps = 152/1787 (8%)
Query: 2336 QCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 2395
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 2396 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGC-VAVGSTTCQ 2454
+ YY G ++ P C CRC G V C+ S CG H C+ G GC G+ TC
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
Query: 2455 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 2514
GDPHY TFDGR F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYV 1216
Query: 2515 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 2574
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D
Sbjct: 1217 TLPESTVTLLKGR-RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQ 1274
Query: 2575 VRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPP 2633
+ VTV Y +CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC---- 1330
Query: 2634 TCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 2693
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 1331 ----QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMC 1386
Query: 2694 LGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSAL 2753
G +LC+++ + CQ AG V+PWR FCPM CP NS Y LCA C C +
Sbjct: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
Query: 2754 SAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYH-NGAYYEPEQTVLIDNCRQQCTC 2812
+ + C D C E C+C+ GF+ +G C+P QCGC H G+Y++ + C++ C C
Sbjct: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC 1506
Query: 2813 HVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 2872
+ CQ C R QE C +Q G C A
Sbjct: 1507 ESNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAA 1540
Query: 2873 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN-PAVS 2931
TC GDPHY +FDG F GTC YVL P S + F V+ N+NRG VS
Sbjct: 1541 TCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVS 1597
Query: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 2991
Y++ V V +IS+ + KV +NG ALPV +A GR+++ ++ LL +FGLQ
Sbjct: 1598 YIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
Query: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GW 3050
V YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESS 1715
Query: 3051 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110
+P C+ G +C E+ + + P GPF+ CH VPP+S F CV
Sbjct: 1716 EPGCF-LVGGKPSSCQENSMADAWNKNCAILINP--QGPFSQCHQVVPPQSSFASCVHGQ 1772
Query: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 3170
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C S
Sbjct: 1773 CGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS 1831
Query: 3171 PAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADG 3227
+ P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 1832 ---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTEN 1887
Query: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 3287
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 1888 TCTRLCTCSV-HNNITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDGS 1945
Query: 3288 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLSA 3346
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 1946 NHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQK 2004
Query: 3347 RWPRKLQVDGVFVTLPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAAY 3404
++ ++ VTLP + + + + + +V G+ + FDG+ + + +P Y
Sbjct: 2005 --GHRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
Query: 3405 AGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPC----------T 3454
G +CG+CGN+N + D+L + A ++ K C
Sbjct: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQIP 2118
Query: 3455 PEQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHPG 3505
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 2119 AEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
Query: 3506 GLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAP-EGC 3564
LC A+ + A CQ+ G + WR FCP +CPA+S Y C SC SC L EG
Sbjct: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGA 2238
Query: 3565 E--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DDRYYPLGQTFYPGPGCDSLCRCREG 3621
+ SAC EGC+C G+VLS D CVP QCGC PLG++ + GC C C G
Sbjct: 2239 KVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC-TG 2296
Query: 3622 GEVSCEPSSC--GPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYV 3679
G + C C G H + CV+ S C GDP Y TFDG + G YV
Sbjct: 2297 GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYV 2356
Query: 3680 LAQTCGTRP-GLHRFAVLQEN-VAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 3737
L +T P G+ V N + + + VIT V + ++L Q ++ VN
Sbjct: 2357 LIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT-VYGYKVQL-QAGLELVVNNQK 2414
Query: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797
M +P N +R + G + + TDF L V++ +++P Y L+ GLCGNY+
Sbjct: 2415 MAVP-YRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDK 2473
Query: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAG---------CIPSDK 3848
+ K+D P+G+ N N FGNSWE D+ P P G + +
Sbjct: 2474 NRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSE 2533
Query: 3849 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 3908
C PE + + C +L+ P GP ++CH+ V P+ + C+ DLC
Sbjct: 2534 CSPE-QLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQ-------DPRE 2585
Query: 3909 AYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGC 3968
CQ GH H DT + C G G
Sbjct: 2586 QEELRCQVLSGH------------GVSSRYHISELYDTL--------PSILCQPGRPRGL 2625
Query: 3969 Q--CDSGFLYNGQACV------PIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVV 4020
+ + + C+ P+ CGC NG+YY+ + L ++C Q+CTC ++++
Sbjct: 2626 RGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILL 2685
Query: 4021 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 4067
C+ SC+ G+VC C + PC C+ C+EQG C
Sbjct: 2686 CEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCREQGATFTC 2732
Score = 874 bits (2257), Expect = 0.0
Identities = 562/1756 (32%), Positives = 788/1756 (44%), Gaps = 152/1756 (8%)
Query: 1950 CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2009
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 2010 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 2068
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 2069 TAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 2128
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 2129 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLA 2188
V + + ++TL R+ V G VTLP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 2189 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 2238
+DGD + + V + Y+G LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 2239 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 2298
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 2299 VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLS 2358
QG LC ++T CQ AG ++ WR P FCP CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 2359 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSLCRC 2417
+ C C E C C+ GFVLSG C+P QCGCLH Y+ +G+ +Y PGC LC C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 2418 REGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVY 2477
+ C+P C E C G GC A G+ TC ASGDPHY TFDG FMGTC Y
Sbjct: 1507 ESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTY 1566
Query: 2478 VLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVNGVD 2536
VL + C +R F V N G G + V+ + V V F L + R KV +NG
Sbjct: 1567 VLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 2537 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 2596
+ LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y +CGLCGNYN
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656
+ DD +P+ AG++ + G +W+ +P+S GC P ++
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWK--LPES----------SEPGCFLVGGKPSSCQENS 1733
Query: 2657 QKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713
+ + C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C
Sbjct: 1734 MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC 1793
Query: 2714 QAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQCDS 2771
A GQ WRN TFCPM CP S Y C+ C CS+++ P CP CAE C+C
Sbjct: 1794 -AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQK 1852
Query: 2772 GFLYNGQACVPIQQCGCYHNGAYYEP--EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 2829
G + +G +CVP+ QCGC Y P E+ + C + CTC V + C + +CKP Q
Sbjct: 1853 GHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQ 1912
Query: 2830 VCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 2889
+C G+L C G GV C L G+ HY SFDG
Sbjct: 1913 ICWALDGLLRC------------------RASGVGV--------CQLPGESHYVSFDGSN 1946
Query: 2890 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NRGNPAVSYVRVVTVAALGTNISIH 2948
C VL P ++ L F ++ K++ G + V + +++
Sbjct: 1947 HSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
Query: 2949 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 3008
K +V +N LP +SV + +++ G+QV +D N +++ +P++Y
Sbjct: 2004 KGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
Query: 3009 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 3068
+G VCG+CGN + ++ + P+ +A S + SW+ DP C+ +
Sbjct: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDP----SCQSLLVDEQQI 2117
Query: 3069 RLEQYEGP-GFCGPL----------APGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 3117
EQ E P G C A + C + + F C +C GG
Sbjct: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
Query: 3118 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 3177
LC+AL ++ A CQ+ G+ WR C + CP S Y C P C SC
Sbjct: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 3178 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 3236
A C EGC C G+VLS D+CVP + CGC A+G G W C++ C C
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC- 2294
Query: 3237 PGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 3295
GG++ C C G C L + C + +C +GDP Y+T DG + QG
Sbjct: 2295 -TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
Query: 3296 EYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Y+L P G E V N+ ++ + + V +Y + + L A +L V+
Sbjct: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQA--GLELVVN 2411
Query: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
+ +P++ + L L G + + T L ++F G + +P+ Y G + GLCGNY
Sbjct: 2412 NQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNY 2471
Query: 3416 NQDPADDLKAVGGKPA--------GWQV--------------GGAQGCGECVSKPC---P 3450
+++ +D+ G W+V +G G +
Sbjct: 2472 DKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQV 2531
Query: 3451 SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 3510
S C+PEQ S AC V++ GP A CH V P + + C+LD C Q
Sbjct: 2532 SECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQD-------- 2582
Query: 3511 VATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE 3570
+ E R + H D+ P P G R
Sbjct: 2583 -----------PREQEELRCQVLSGHGVSSRYHISELYDTLPSILCQPGRPRGLRGPLRG 2631
Query: 3571 GCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS 3630
L P+ CGC + YY LG +F C C C + CEP S
Sbjct: 2632 RLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLCEPFS 2690
Query: 3631 CGPHETCRPSGGSLGC 3646
C E C + GC
Sbjct: 2691 CRAGEVCTLGNHTQGC 2706
Score = 866 bits (2238), Expect = 0.0
Identities = 564/1756 (32%), Positives = 814/1756 (46%), Gaps = 154/1756 (8%)
Query: 3537 QCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 3596
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 3597 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGC-VAVGSTTCQ 3655
+ YY G ++ P C CRC G V C+ S CG H C+ G GC G+ TC
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
Query: 3656 ASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 3715
GDPHY TFDG F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYV 1216
Query: 3716 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 3775
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D
Sbjct: 1217 TLPESTVTLLKGR-RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQ 1274
Query: 3776 VRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPP 3834
+ VTV Y +CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC---- 1330
Query: 3835 TCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 3894
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 1331 ----QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMC 1386
Query: 3895 LGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSAL 3954
G +LC+++ + CQ AG V+PWR FCPM CP NS Y LCA C C +
Sbjct: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
Query: 3955 SAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTC 4013
+ + C D C E C+C+ GF+ +G C+P QCGC H G Y++ + C++ C C
Sbjct: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC 1506
Query: 4014 HVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 4073
+ CQ C R QE C +Q G C A
Sbjct: 1507 ESNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAA 1540
Query: 4074 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN-PAVS 4132
TC GDPHY +FDG F GTC YVL P S + F V+ N+NRG VS
Sbjct: 1541 TCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVS 1597
Query: 4133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 4192
Y++ V V +IS+ + KV +NG ALPV +A GR+++ ++ LL +FGLQ
Sbjct: 1598 YIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
Query: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GW 4251
V YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESS 1715
Query: 4252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311
+P C+ G +C E+ + C L + GPF+ CH VPP+S F CV
Sbjct: 1716 EPGCF-LVGGKPSSCQENSMADAWNKN-CAILIN-PQGPFSQCHQVVPPQSSFASCVHGQ 1772
Query: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C S
Sbjct: 1773 CGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS 1831
Query: 4372 PAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADG 4428
+ P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 1832 ---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTEN 1887
Query: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 4488
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 1888 TCTRLCTCSV-HNNITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDGS 1945
Query: 4489 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLSA 4547
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 1946 NHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQK 2004
Query: 4548 RWPRKLQVDGVFVALPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAAY 4605
++ ++ V LP + + + + + +V G+ + FDG+ + + +P Y
Sbjct: 2005 --GHRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
Query: 4606 AASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPC----------T 4655
+CG+CGN+N + D+L + A ++ K C
Sbjct: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQIP 2118
Query: 4656 PEQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHPG 4706
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 2119 AEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
Query: 4707 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGC 4765
LC A+ + A CQ+ G + WR FCPL+CPA+S Y C SC SC L EG
Sbjct: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGA 2238
Query: 4766 E--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DGRYYPLGEVFYPGPECERRCECGPG 4822
+ SAC EGC+C G+VLS D CVP QCGC G PLG+ + C +C C G
Sbjct: 2239 KVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGK-SWVSSGCTEKCVC-TG 2296
Query: 4823 GHVTCQE-GAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 4881
G + C + G H + ++ C + +C G Y+T DG Y L G +YV
Sbjct: 2297 GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYV 2356
Query: 4882 LAQVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAVA 4935
L + P + +V +N LQ ++ TV G V L G ++ V+ + +A
Sbjct: 2357 LIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMA 2416
Query: 4936 LPVAVG-RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 4994
+P +RVT G+ + L T L + F G + ++S+PS + G + GLCGN++ N
Sbjct: 2417 VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRK 2476
Query: 4995 DDFVLPNGSAASSVETFGAAWRA-------------PGSSKGCGEGCGPQ-GCPV--CLA 5038
+D +LP+G+ ++ TFG +W P +G G G + G V C
Sbjct: 2477 NDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSP 2536
Query: 5039 EETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLA 5095
E+ A S +AC L +PQGPFA C ++P + CV DLC+ + + C+ L+
Sbjct: 2537 EQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLS 2595
Query: 5096 AYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ-GSCAALSG-LTGCTTRCFE 5153
+ GV+ + + + + ++ + CQ G L G L G +
Sbjct: 2596 GH-------GVSSR----------YHISELYDTLPSILCQPGRPRGLRGPLRGRLRQ--- 2635
Query: 5154 GCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGC 5213
R L P+ DCGCT NG Y + SS LT DCS+RC+C+SS L C+ C
Sbjct: 2636 ----HPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLTEDCSQRCTCASSRILLCEPFSC 2691
Query: 5214 PPGRVCEVKAEARNCW 5229
G VC + + C+
Sbjct: 2692 RAGEVCTLGNHTQGCF 2707
Score = 866 bits (2237), Expect = 0.0
Identities = 563/1757 (32%), Positives = 791/1757 (45%), Gaps = 153/1757 (8%)
Query: 3151 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 3210
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 3211 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 3269
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 3270 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 3329
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 3330 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLA 3389
V + + ++TL R+ V G VTLP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 3390 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 3439
+DGD + + V + Y+G LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 3440 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 3499
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 3500 VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLS 3559
QG LC ++T CQ AG ++ WR P FCP CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 3560 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSLCRC 3618
+ C C E C C+ GFVLSG C+P QCGCLH Y+ +G+ +Y PGC LC C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 3619 REGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVY 3678
+ C+P C E C G GC A G+ TC ASGDPHY TFDG FMGTC Y
Sbjct: 1507 ESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTY 1566
Query: 3679 VLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVNGVD 3737
VL + C +R F V N G G + V+ + V V F L + R KV +NG
Sbjct: 1567 VLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797
+ LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y +CGLCGNYN
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857
+ DD +P+ AG++ + G +W+ +P+S P C G PS + +
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWK--LPES---SEPGC--FLVGGKPSSCQENSMADAW 1738
Query: 3858 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 3917
K C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C A
Sbjct: 1739 NKN--CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC-AQ 1795
Query: 3918 GGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQCDSGFL 3975
G WRN TFCPM CP S Y C+ C CS+++ P CP CAE C+C G +
Sbjct: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855
Query: 3976 YNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQ 4033
+G +CVP+ QCGC Y P E+ + C + CTC V + C + +CKP Q+C
Sbjct: 1856 LSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICW 1915
Query: 4034 PSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDF 4093
G+L C G GV C L G+ HY SFDG
Sbjct: 1916 ALDGLLRC------------------RASGVGV--------CQLPGESHYVSFDGSNHSI 1949
Query: 4094 QGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NRGNPAVSYVRVVTVAALGTNISIHKDE 4152
C VL P ++ L F ++ K++ G + V + +++ K
Sbjct: 1950 PDACTLVLVKVCHPAMA---LPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH 2006
Query: 4153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 4212
+V +N LP +SV + +++ G+QV +D N +++ +P++Y+G
Sbjct: 2007 --RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGK 2064
Query: 4213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLC--------------WDE 4258
VCG+CGN + ++ + P+ +A S + SW+ DP C +
Sbjct: 2065 VCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQEN 2124
Query: 4259 CRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 4318
G+C R + P+ + C + + F C +C GG
Sbjct: 2125 PSGNCRAADLRRAREKCEAALRAPV-------WAQCASRIDLTPFLVDCANTLCEFGGLY 2177
Query: 4319 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 4378
LC+AL ++ A CQ+ G+ WR C + CP S Y C P C SC
Sbjct: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 4379 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 4437
A C EGC C G+VLS D+CVP + CGC A+G G W C++ C C
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC- 2294
Query: 4438 PGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 4496
GG++ C C G C L + C + +C +GDP Y+T DG + QG
Sbjct: 2295 -TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
Query: 4497 EYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Y+L P G E V N+ ++ + + V +Y + + L A +L V+
Sbjct: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQA--GLELVVN 2411
Query: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
+A+P++ + L L G + + T L ++F G + +P+ Y + GLCGNY
Sbjct: 2412 NQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNY 2471
Query: 4617 NQDPADDLKAVGGKPA--------GWQV--------------GGAQGCGECVSKPC---P 4651
+++ +D+ G W+V +G G +
Sbjct: 2472 DKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQV 2531
Query: 4652 SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 4711
S C+PEQ S AC V++ GP A CH V P + + C+LD C Q P
Sbjct: 2532 SECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQD------PR 2584
Query: 4712 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE 4771
+ CQ + H D+ P P G R
Sbjct: 2585 EQEEL-RCQVLSGH------------GVSSRYHISELYDTLPSILCQPGRPRGLRGPLRG 2631
Query: 4772 GCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGA 4831
L P+ CGC +G YY LG F +C +RC C + C E
Sbjct: 2632 RLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLC-EPF 2689
Query: 4832 ACGPHEECRLEDGVQAC 4848
+C E C L + Q C
Sbjct: 2690 SCRAGEVCTLGNHTQGC 2706
Score = 850 bits (2195), Expect = 0.0
Identities = 567/1783 (31%), Positives = 796/1783 (44%), Gaps = 161/1783 (9%)
Query: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 1591
CPPN+ YE CA C C S P C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 1592 VYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 1651
YYEP NC + C C G + CQ C VCQ G C P G
Sbjct: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
Query: 1652 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 1711
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
Query: 1712 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 1771
F VT KN+ +G VS + V V + +++ K + V G LP + G
Sbjct: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG- 1247
Query: 1772 ISVTQGASKAL--LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 1829
V GAS L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +
Sbjct: 1248 --VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
Query: 1830 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
+G+ A G SW+ D C + P+C GPGFCG L T GP
Sbjct: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
Query: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
F TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C +
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1949 TCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 2008
CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CG
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
Query: 2009 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 2067
C G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
Query: 2068 STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 2126
A C A GDPHY+T DG +F GTC Y+L+ PC + F V+ NE+RG V
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
Query: 2127 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTTTSGL 2185
SY ++V + +++ S++L K+ ++G V LP L + LS V++ T GL
Sbjct: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
Query: 2186 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 2243
+ +DG V + VP++Y G LCGLCGNYN + DD K AG Q+G A E
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
Query: 2244 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2297
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 2298 QVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSL 2357
+G LC ++ Y + C AG Q WR FCP +CP S Y C CP +C S+
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 2358 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSL 2414
+ P C A C E C C G +LSG +CVP+GQCGC Y+P+G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 2415 CRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGT 2474
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 2475 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 2533
C VL + C L F + ++ G R+ V + + ++ Q+ +V +N
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
Query: 2534 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 2593
+ LP + + ++ G++V +D + + + +P YY +CG+CGN
Sbjct: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
Query: 2594 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPPTCPPGSEGCIPSEEC-P 2649
+N + +D+ P+ A + +EF NSW++ D C L P + PS C
Sbjct: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
Query: 2650 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 2709
+L + +K E L +P + C +D L DC LC GG LC + A+
Sbjct: 2132 ADLRRAREKCE--AALRAPVW--AQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
Query: 2710 VSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ---CPDGCAEG 2766
+ CQ+ G + WRN +FCP+ECP S Y C +CS C L + P CAEG
Sbjct: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
Query: 2767 CQCDSGFLYNGQACVPIQQCGCYH-NGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 2825
C C G++ + CVP QCGC +G ++ + C ++C C G + C + C
Sbjct: 2248 CICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRC 2306
Query: 2826 KPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSF 2885
G CQ + C+ + C ++GDP Y +F
Sbjct: 2307 PSGSHCQLTS------------------------DNSNSNCVSDKSEQCSVYGDPRYLTF 2342
Query: 2886 DGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNI 2945
DG + QG YVL T V +G+ P V +N+ + +++ V G +
Sbjct: 2343 DGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
Query: 2946 SIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLP 3005
+ ++ VN A+P + + VT + LV DF L VS+ ++LP
Sbjct: 2401 QLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
Query: 3006 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL--------CWDE 3057
S Y G V GLCGN D+N ND + P+G L ++ +G SW D L +E
Sbjct: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
Query: 3058 CRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVL 3108
+G+ C ++L C LA GPF CH V PE F + CVL
Sbjct: 2518 GQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLA-DPQGPFAACHQTVAPEPFQEHCVL 2575
Query: 3109 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 3168
D+C R+ E+ R QV H P+
Sbjct: 2576 DLCSAQDPRE-------------------QEELRCQVLSGHGVSSRYHISELYDTLPSIL 2616
Query: 3169 PSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGT 3228
P P GP + L PL + CGC +NG Y++ GS F +
Sbjct: 2617 CQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-CGCTSNGIYYQLGSSFLTE-D 2671
Query: 3229 CSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQPVS 3269
CSQ C C L+C P SC GEVC L G H GC P S
Sbjct: 2672 CSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCFPES 2710
Score = 842 bits (2176), Expect = 0.0
Identities = 552/1779 (31%), Positives = 789/1779 (44%), Gaps = 140/1779 (7%)
Query: 718 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 777
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
Query: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
Query: 838 KQSCPAGERCSVQNGLLGCYP-DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 896
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Query: 897 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 956
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLK--GRRTLVGGQQVTLPAIPS 1245
Query: 957 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1016
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
Query: 1017 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVH- 1193
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Query: 1194 QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1253
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
Query: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
Query: 1314 QVANFTLRLE-QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVY 1372
V F L + R KV +NG + LPV LA G++ + V++ T+FGL+V YD +
Sbjct: 1603 HVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSH 1662
Query: 1373 YVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT 1432
V VTVP +Y Q+CGLCGNYN + DD +P+ AG++ + G +W+ +P+S
Sbjct: 1663 LVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWK--LPES------ 1714
Query: 1433 PCPPGSEDCIPSHKCPPELEKKYQKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIF 1489
PG C P ++ + + C +L +P GP S CH++V PQ C+
Sbjct: 1715 -SEPG---CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVH 1770
Query: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
C G+ + LC ++ AY S C A G WR TFCPM CPP S Y C+ C C
Sbjct: 1771 GQCGTKGDTTALCRSLQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
Query: 1550 SALSAPPQCQDG--CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNC 1605
S+++ P C CAE C+C G + +G +CVP+ QCGC Y P E+ + C
Sbjct: 1830 SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTC 1889
Query: 1606 RQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
+ CTC + C + +CKP Q+C G+L C G GV
Sbjct: 1890 TRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC------------------RASGVGV- 1930
Query: 1666 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NR 1724
C L G+ HY SFDG C VL P ++ L F ++ K++
Sbjct: 1931 -------CQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEE 1980
Query: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 1784
G + V + +++ K +V +N LP +SV + +++
Sbjct: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
Query: 1785 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 1844
G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A S + SW
Sbjct: 2039 IKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSW 2098
Query: 1845 RAPGWDPLCWDECRGSCPTCPEDRLEQYEGP-GFCGPL----------APGTGGPFTTCH 1893
+ DP C+ + EQ E P G C A + C
Sbjct: 2099 KDKDIDP----SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCA 2154
Query: 1894 AHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 1953
+ + F C +C GG LC+AL ++ A CQ+ G+ WR C + CP
Sbjct: 2155 SRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAY 2214
Query: 1954 SHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-AN 2012
S Y C C SC A C EGC C G+VLS D+CVP + CGC A+
Sbjct: 2215 SSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAH 2273
Query: 2013 GTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAE 2071
G G W C++ C C GG++ C C G C L + C + +
Sbjct: 2274 GGSIPLGKS-WVSSGCTEKCVC--TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQ 2330
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131
C +GDP Y+T DG + QG Y+L P G E V N+ ++ + +
Sbjct: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
Query: 2132 VTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
V +Y + + L A +L V+ + +P++ + L L G + + T L ++F G
Sbjct: 2391 VITTVYGYKVQLQA--GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGG 2448
Query: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQV--------- 2234
+ +P+ Y G + GLCGNY+++ +D+ G W+V
Sbjct: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
Query: 2235 -----GGAQGCGECVSKPC---PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 2286
+G G + S C+PEQ S AC V++ GP A CH V P
Sbjct: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPE 2567
Query: 2287 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC 2346
+ + C+LD C Q + E R + H
Sbjct: 2568 PFQEHCVLDLCSAQD-------------------PREQEELRCQVLSGHGVSSRYHISEL 2608
Query: 2347 GDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFY 2406
D+ P P G R L P+ CGC + YY LG +F
Sbjct: 2609 YDTLPSILCQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGSSFL 2668
Query: 2407 PGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGC 2445
C C C + CEP SC E C + GC
Sbjct: 2669 T-EDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGC 2706
Score = 838 bits (2165), Expect = 0.0
Identities = 566/1783 (31%), Positives = 792/1783 (44%), Gaps = 161/1783 (9%)
Query: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 2792
CP N+ YE CA C C S C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 2793 AYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCR 2852
YYEP NC + C C G V CQ C VCQ G C P G
Sbjct: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
Query: 2853 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 2912
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
Query: 2913 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 2972
F VT KN+ +G VS + V V + +++ K + V G LP + G
Sbjct: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG- 1247
Query: 2973 ISVTQGASKAL--LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
V GAS L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +
Sbjct: 1248 --VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
Query: 3031 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGP 3089
+G+ A G SW+ D C + P+C GPGFCG L T GP
Sbjct: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
Query: 3090 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 3149
F TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C +
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 3150 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 3209
CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CG
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
Query: 3210 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 3268
C G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
Query: 3269 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 3327
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG V
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
Query: 3328 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTTTSGL 3386
SY ++V + +++ S++L K+ ++G V LP L + LS V++ T GL
Sbjct: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
Query: 3387 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 3444
+ +DG V + VP++Y G LCGLCGNYN + DD K AG Q+G A E
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
Query: 3445 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 3498
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 3499 QVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSL 3558
+G LC ++ Y + C AG Q WR FCP +CP S Y C CP +C S+
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 3559 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSL 3615
+ P C A C E C C G +LSG +CVP+GQCGC Y+P+G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 3616 CRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGT 3675
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 3676 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 3734
C VL + C L F + ++ G R+ V + + ++ Q+ +V +N
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
Query: 3735 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 3794
+ LP + + ++ G++V +D + + + +P YY +CG+CGN
Sbjct: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
Query: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPPTCPPGSAGCIPSDKC-P 3850
+N + +D+ P+ A + +EF NSW++ D C L P PS C
Sbjct: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
Query: 3851 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 3910
+L + +K E L +P + C +D L DC LC GG LC + A+
Sbjct: 2132 ADLRRAREKCE--AALRAPVW--AQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
Query: 3911 VSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ---CPDGCAEG 3967
+ CQ+ G WRN +FCP+ECP S Y C +CS C L + P CAEG
Sbjct: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
Query: 3968 CQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 4026
C C G++ + CVP QCGC +G ++ + C ++C C G + C + C
Sbjct: 2248 CICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRC 2306
Query: 4027 KPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSF 4086
G CQ +T D C+ + C ++GDP Y +F
Sbjct: 2307 PSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPRYLTF 2342
Query: 4087 DGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNI 4146
DG + QG YVL T V +G+ P V +N+ + +++ V G +
Sbjct: 2343 DGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
Query: 4147 SIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLP 4206
+ ++ VN A+P + + V + LV DF L VS+ ++LP
Sbjct: 2401 QLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
Query: 4207 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL--------CWDE 4258
S Y G V GLCGN D+N ND + P+G L ++ +G SW D L +E
Sbjct: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
Query: 4259 CRGS---------CPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVL 4309
+G+ C ++L C L+ GPF CH V PE F + CVL
Sbjct: 2518 GQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLAD-PQGPFAACHQTVAPEPFQEHCVL 2575
Query: 4310 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASC 4369
D+C R+ E+ R QV H P+
Sbjct: 2576 DLCSAQDPRE-------------------QEELRCQVLSGHGVSSRYHISELYDTLPSIL 2616
Query: 4370 PSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGT 4429
P P GP + L PL + CGC +NG Y++ GS F +
Sbjct: 2617 CQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-CGCTSNGIYYQLGSSFLTE-D 2671
Query: 4430 CSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQPVS 4470
CSQ C C L+C P SC GEVC L G H GC P S
Sbjct: 2672 CSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCFPES 2710
Score = 817 bits (2111), Expect = 0.0
Identities = 537/1667 (32%), Positives = 762/1667 (45%), Gaps = 125/1667 (7%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
Query: 503 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
Query: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
Query: 623 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
Query: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
Query: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
Query: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 920
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
Query: 921 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 980
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
Query: 981 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1038
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
Query: 1039 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 1097 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1156
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 1157 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1213
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 1274 CVYVLAQTCGTRPGLHRFAV--LQENVAWGNGRVSVTRV-ITVQVANFTLRLEQRQWKVT 1330
C VL + C L F + E G + V I + A TL Q+ +V
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTL---QKGHRVL 2009
Query: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLC 1390
+N + LP + + ++ G++V +D + + + +P YY ++CG+C
Sbjct: 2010 INSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMC 2069
Query: 1391 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC 1447
GN+N + +D+ P+ A + +EF NSW++ D C L P + PS C
Sbjct: 2070 GNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNC 2129
Query: 1448 -PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 1506
+L + +K E L +P + C +D L DC LC GG LC +
Sbjct: 2130 RAADLRRAREKCE--AALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQ 2185
Query: 1507 AYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQ-----DG 1561
A+ + CQ+ G WR +FCP+ECP S Y C +CS C L +C+
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSA 2243
Query: 1562 CAEGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
CAEGC C G++ + CVP QCGC +G ++ + C ++C C G + C
Sbjct: 2244 CAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCG 2302
Query: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
+ C G CQ +T D C+ + C ++GDP
Sbjct: 2303 DFRCPSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPR 2338
Query: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
Y +FDG + QG YVL T V +G+ P V +N+ + +++ V
Sbjct: 2339 YLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVY 2396
Query: 1741 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 1800
G + + ++ VN A+P + + VT + LV DF L VS+
Sbjct: 2397 GYKVQLQAGL--ELVVNNQKMAVPYR-PNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAV 2453
Query: 1801 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL-------- 1852
++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D L
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
Query: 1853 CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFK 1903
+E +G+ C ++L C LA GPF CH V PE F +
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLA-DPQGPFAACHQTVAPEPFQE 2571
Query: 1904 GCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPC 1963
CVLD+C R+ E+ R QV H
Sbjct: 2572 HCVLDLCSAQDPRE-------------------QEELRCQVLSGHGVSSRYHISELYDTL 2612
Query: 1964 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 2023
P+ P P GP + L PL + CGC +NG Y++ GS F
Sbjct: 2613 PSILCQPG---RPRGLRGPLRGRLRQHPRLCLQWHPEPPLAD-CGCTSNGIYYQLGSSFL 2668
Query: 2024 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH--GCQPVS 2068
+ CSQ C C L+C P SC GEVC L G H GC P S
Sbjct: 2669 TE-DCSQRCTCA-SSRILLCEPFSCRAGEVCTL---GNHTQGCFPES 2710
Score = 745 bits (1923), Expect = 0.0
Identities = 483/1508 (32%), Positives = 696/1508 (46%), Gaps = 132/1508 (8%)
Query: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 3993
CP N+ YE CA C C S C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 3994 VYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 4053
YYEP NC + C C G V CQ C VCQ G C P G
Sbjct: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
Query: 4054 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 4113
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
Query: 4114 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 4173
F VT KN+ +G VS + V V + +++ K + V G LP + G
Sbjct: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKGV 1248
Query: 4174 ISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND + +G
Sbjct: 1249 FLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG 1307
Query: 4234 TLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFT 4292
+ A G SW+ D C + P+C GPGFCG L T GPF
Sbjct: 1308 SPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGPFE 1366
Query: 4293 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 4352
TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C + C
Sbjct: 1367 TCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
Query: 4353 PENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW 4412
P NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CGC
Sbjct: 1427 PPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CGCL 1482
Query: 4413 -ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST 4471
G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 1483 HPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQGA 1539
Query: 4472 AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSY 4530
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG VSY
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEVSY 1598
Query: 4531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSL 4589
++V + +++ S++L K+ ++G VALP L + LS V++ T GL +
Sbjct: 1599 IKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
Query: 4590 AFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGECVS 4647
+DG V + VP++Y LCGLCGNYN + DD K AG Q+G A E
Sbjct: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSE 1716
Query: 4648 KPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQV 4701
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 1717 PGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
Query: 4702 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 4761
+G LC ++ Y + C AG Q WR FCP++CP S Y C CP +C S++
Sbjct: 1776 KGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINN 1834
Query: 4762 PEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCE 4818
P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y C R C
Sbjct: 1835 PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCT 1894
Query: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 4878
C ++TC + + C P++ C DG+ C A+G G C G HY++ DG + + +C
Sbjct: 1895 CSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDAC 1953
Query: 4879 SYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQGQQVTVDGE 4932
+ VL +VCHP F I EK G L + + + V+L +G +V ++ +
Sbjct: 1954 TLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSK 2013
Query: 4933 AVALPVA--VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN 4990
V LP + V V + ++ G+++ FDG+ L + IP+ + G++CG+CGNFN
Sbjct: 2014 QVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFN 2073
Query: 4991 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 5050
D+ ++P+ A+S F +W+ C + + E+ P E E
Sbjct: 2074 DEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQIPAEQQE-- 2123
Query: 5051 GQLRNPQGP---------------------FATCQAVLSPSEYFRQCVYDLCAQKGDKAF 5089
NP G +A C + + + + C LC G
Sbjct: 2124 ----NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQA 2179
Query: 5090 LCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL---TG 5146
LC++L A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L G
Sbjct: 2180 LCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAK 2239
Query: 5147 CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSG 5205
+ C EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+C C+ +
Sbjct: 2240 VPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA- 2298
Query: 5206 LTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRC 5265
+ C CP G C++ ++ N CV + + R T Y L R
Sbjct: 2299 IQCGDFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
Query: 5266 P-GLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 5323
L T+ E + G+ + + IF Q+ + T+ K GL + + +
Sbjct: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQ 2413
Query: 5324 KLASVSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGN 5374
K+A V P+ L V + V G + + + + G + G CGN
Sbjct: 2414 KMA---VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGN 2470
Query: 5375 FDGDQTND 5382
+D ++ ND
Sbjct: 2471 YDKNRKND 2478
Score = 646 bits (1667), Expect = 0.0
Identities = 392/1088 (36%), Positives = 549/1088 (50%), Gaps = 63/1088 (5%)
Query: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 4411
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 4412 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 4470
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 4471 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 4530
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 4531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 4590
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 4591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 4640
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 4641 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 4700
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 4701 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 4760
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 4761 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 4819
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 4820 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 4879
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
Query: 4880 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 4933
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 4934 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 4991
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 4992 NWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 5049
N DD + P+ A GAAW+ P SS+ GC G P C E + N+
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
Query: 5050 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 5109
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
Query: 5110 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 5167
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
Query: 5168 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 5225
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
Query: 5226 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 5283
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
Query: 5284 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 5340
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
Query: 5341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 5394
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 5395 WRAQDFSP 5402
W+ +D P
Sbjct: 2098 WKDKDIDP 2105
Score = 597 bits (1539), Expect = e-169
Identities = 392/1267 (30%), Positives = 580/1267 (45%), Gaps = 93/1267 (7%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
C+ +C A + C G GC A+ A C A GDPHY TFDG + MGTC+Y + C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCW 1573
Query: 504 EDDTLPAFSVEAKNEHRGS-RRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
F V A NE+RG VSY+ V V + S+SL RG V+++ R LPV
Sbjct: 1574 SRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCK--VMLNGHRVALPVW 1631
Query: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
L++GR+ + S ++ FGL V YD + +++P+ + Q+CGLCGNYN + DD
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDN 1691
Query: 623 LTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTKL 680
L PD LA D+++ ++WKL + E GC P+ + ++ C +L
Sbjct: 1692 LRPDRKLAGDSMQLGAAWKLPESS---EPGCFLVGGKPSSCQENSMADAWNKNCAILINP 1748
Query: 681 DGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN 740
GPF+ CH + P+ CV+ C G+ +LCR L AYA C + G + WR+
Sbjct: 1749 QGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQAPA-WRNRTF 1807
Query: 741 CPLSCPANSRYELCGPACPTSCNGAAAPSNC-SGRPCVEGCVCLPGFVASGGACVPASSC 799
CP+ CP S Y C CP +C+ P +C PC E C C G + SG +CVP C
Sbjct: 1808 CPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQC 1867
Query: 800 GCTFQGLQLAPGQEVWADE-LCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
GCT P E W E C R CTC+ + +TC + +C + C +GLL C
Sbjct: 1868 GCTDPAGSYHPVGERWYTENTCTRLCTCS-VHNNITCF-QSTCKPNQICWALDGLLRCRA 1925
Query: 859 DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVS 918
G CQ G+ HYVSFDG CT +LV C ALP F++ ++E T +
Sbjct: 1926 SGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMALPFFKISAKHEKEEGGTEA 1985
Query: 919 YT-RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 977
+ V ++ +V +++ + +VL++ LP + V V ++V G+
Sbjct: 1986 FRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGV 2043
Query: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE-ET 1036
V +D N + ++P++Y +CG+CGNFN + D+L + A + F NSW++ +
Sbjct: 2044 QVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDI 2103
Query: 1037 RPGCGA---------TEPGDCPKLDSLVAQQLQSKNECGILADPKGP-FRECHSKLDPQG 1086
P C + E + P + A +++ +C A + P + +C S++D
Sbjct: 2104 DPSCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCE--AALRAPVWAQCASRIDLTP 2161
Query: 1087 AVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACS 1146
+ DC C G LC AL + A CQ+ G WR+ CPL CP +S Y C
Sbjct: 2162 FLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCL 2221
Query: 1147 YGCPLSCGDLPVPGGCG-----SECHEGCVCDEGFALSGESCLPLASCGC--VHQGTYHP 1199
C SC DL G C S C EGC+C G+ LS + C+P + CGC H G+ P
Sbjct: 2222 PSCSPSCWDLD--GRCEGAKVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSI-P 2278
Query: 1200 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQ--PSGGSLGCVAVGSSTCQASGD 1257
G+++ GC C C GG + C C CQ + CV+ S C GD
Sbjct: 2279 LGKSWVSS-GCTEKCVCT-GGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGD 2336
Query: 1258 PHYTTFDGRRFDFMGTCVYVLAQTCGTRP-GLHRFAVLQEN-VAWGNGRVSVTRVITVQV 1315
P Y TFDG + G YVL +T P G+ V N + + + VIT V
Sbjct: 2337 PRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT-V 2395
Query: 1316 ANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR 1375
+ ++L Q ++ VN M +P N +R + G + + TDF L V++
Sbjct: 2396 YGYKVQL-QAGLELVVNNQKMAVPY-RPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAV 2453
Query: 1376 VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCP 1435
+++P Y + GLCGNY+ + K+D P+G+ N N FGNSWE D+ P P
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
Query: 1436 P---------GSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 1486
G + +C PE + + C +L+ P GP ++CH+ V P+ +
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPE-QLASNSTQACRVLADPQGPFAACHQTVAPEPFQEH 2572
Query: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 1546
C+ DLC CQ GH R H DT
Sbjct: 2573 CVLDLCSAQDPRE-------QEELRCQVLSGHGVSSRY------------HISELYDTLP 2613
Query: 1547 LGCSALSAPPQCQDGCAEGCQ--CDSGFLYNGQACV------PIQQCGCYHNGVYYEPEQ 1598
S L CQ G G + + + C+ P+ CGC NG+YY+
Sbjct: 2614 ---SIL-----CQPGRPRGLRGPLRGRLRQHPRLCLQWHPEPPLADCGCTSNGIYYQLGS 2665
Query: 1599 TVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKE 1658
+ L ++C Q+CTC + + ++C+ SC+ G+VC C + PC C+ C+E
Sbjct: 2666 SFLTEDCSQRCTCASSRILLCEPFSCRAGEVCTLGNHTQGCFPESPCLQNPCQNDGQCRE 2725
Query: 1659 QGGQGVC 1665
QG C
Sbjct: 2726 QGATFTC 2732
Score = 376 bits (965), Expect = e-103
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 4738 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 4797
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 4798 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 4856
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
Query: 4857 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 4911
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
Query: 4912 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 4970
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 4971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 5030
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
Query: 5031 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 5090
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
Query: 5091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 5148
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
Query: 5149 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 5207
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
Query: 5208 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 5266
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
Query: 5267 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 5323
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
Query: 5324 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 5382
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
Score = 323 bits (829), Expect = 2e-87
Identities = 235/847 (27%), Positives = 357/847 (42%), Gaps = 87/847 (10%)
Query: 443 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
Query: 503 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPA 2019
Query: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
Query: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 679
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
Query: 680 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 730
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
Query: 731 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 783
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
Query: 784 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
Query: 844 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 901
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
Query: 902 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
Query: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
Query: 1018 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1060
G N FGNSW+ +T A E G +L Q+
Sbjct: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
Query: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1117
S C +LADP+GPF CH + P+ CV D C P + L C L+ + + +
Sbjct: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGHGVSSR 2602
Query: 1118 AAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFA 1177
+ ++ + L + C P P G
Sbjct: 2603 YHISELY----DTLPSILCQPGR------------------PRGLRGPLRGRLRQHPRLC 2640
Query: 1178 LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
L PLA CGC G Y+ G +F C C C ++ CE SC E C
Sbjct: 2641 LQWHPEPPLADCGCTSNGIYYQLGSSFLT-EDCSQRCTCASSRILLCEPFSCRAGEVCTL 2699
Query: 1238 SGGSLGC 1244
+ GC
Sbjct: 2700 GNHTQGC 2706
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 866 bits (2238), Expect = 0.0
Identities = 554/1699 (32%), Positives = 779/1699 (45%), Gaps = 151/1699 (8%)
Query: 1950 CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2009
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 2010 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 2068
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 2069 TAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 2128
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 2129 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLA 2188
V + + ++TL R+ V G VTLP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 2189 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 2238
+DGD + + V + Y+G LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 2239 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 2298
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 2299 VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLS 2358
QG LC ++T CQ AG ++ WR P FCP CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 2359 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSLCRC 2417
+ C C E C C+ GFVLSG C+P QCGCLH Y+ +G+ +Y PGC LC C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 2418 REGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVY 2477
+ C+P C E C G GC A G+ TC ASGDPHY TFDG FMGTC Y
Sbjct: 1507 ESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTY 1566
Query: 2478 VLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVNGVD 2536
VL + C +R F V N G G + V+ + V V F L + R KV +NG
Sbjct: 1567 VLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 2537 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 2596
+ LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y +CGLCGNYN
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656
+ DD +P+ AG++ + G +W+ +P+S GC P ++
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWK--LPES----------SEPGCFLVGGKPSSCQENS 1733
Query: 2657 QKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713
+ + C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C
Sbjct: 1734 MADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC 1793
Query: 2714 QAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQCDS 2771
A GQ WRN TFCPM CP S Y C+ C CS+++ P CP CAE C+C
Sbjct: 1794 -AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQK 1852
Query: 2772 GFLYNGQACVPIQQCGCYHNGAYYEP--EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 2829
G + +G +CVP+ QCGC Y P E+ + C + CTC V + C + +CKP Q
Sbjct: 1853 GHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQ 1912
Query: 2830 VCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRK 2889
+C G+L C G GV C L G+ HY SFDG
Sbjct: 1913 ICWALDGLLRC------------------RASGVGV--------CQLPGESHYVSFDGSN 1946
Query: 2890 FDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NRGNPAVSYVRVVTVAALGTNISIH 2948
C VL P ++ L F ++ K++ G + V + +++
Sbjct: 1947 HSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQ 2003
Query: 2949 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 3008
K +V +N LP +SV + +++ G+QV +D N +++ +P++Y
Sbjct: 2004 KGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
Query: 3009 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 3068
+G VCG+CGN + ++ + P+ +A S + SW+ DP C+ +
Sbjct: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDP----SCQSLLVDEQQI 2117
Query: 3069 RLEQYEGP-GFCGPL----------APGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 3117
EQ E P G C A + C + + F C +C GG
Sbjct: 2118 PAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLY 2177
Query: 3118 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 3177
LC+AL ++ A CQ+ G+ WR C + CP S Y C P C SC
Sbjct: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 3178 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 3236
A C EGC C G+VLS D+CVP + CGC A+G G W C++ C C
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC- 2294
Query: 3237 PGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 3295
GG++ C C G C L + C + +C +GDP Y+T DG + QG
Sbjct: 2295 -TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
Query: 3296 EYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Y+L P G E V N+ ++ + + V +Y + + L A +L V+
Sbjct: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQA--GLELVVN 2411
Query: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
+ +P++ + L L G + + T L ++F G + +P+ Y G + GLCGNY
Sbjct: 2412 NQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNY 2471
Query: 3416 NQDPADDLKAVGGKPA--------GWQV--------------GGAQGCGECVSKPC---P 3450
+++ +D+ G W+V +G G +
Sbjct: 2472 DKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQV 2531
Query: 3451 SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG---HPGGL 3507
S C+PEQ S AC V++ GP A CH V P + + C+LD C Q
Sbjct: 2532 SECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELR 2590
Query: 3508 CPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESA 3567
C ++ Y CQ AGA L WR C C + C + G C A CE
Sbjct: 2591 CQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNP----CQND--GQCREQGATFTCE-- 2642
Query: 3568 CREGCVCDAGFVLSGDTCV 3586
C+ G+ G C+
Sbjct: 2643 ------CEVGY--GGGLCM 2653
Score = 862 bits (2227), Expect = 0.0
Identities = 543/1651 (32%), Positives = 763/1651 (46%), Gaps = 135/1651 (8%)
Query: 3151 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 3210
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 3211 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 3269
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 3270 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 3329
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 3330 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLA 3389
V + + ++TL R+ V G VTLP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 3390 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 3439
+DGD + + V + Y+G LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 3440 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 3499
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 3500 VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLS 3559
QG LC ++T CQ AG ++ WR P FCP CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 3560 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSLCRC 3618
+ C C E C C+ GFVLSG C+P QCGCLH Y+ +G+ +Y PGC LC C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 3619 REGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVY 3678
+ C+P C E C G GC A G+ TC ASGDPHY TFDG FMGTC Y
Sbjct: 1507 ESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTY 1566
Query: 3679 VLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVNGVD 3737
VL + C +R F V N G G + V+ + V V F L + R KV +NG
Sbjct: 1567 VLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797
+ LPV LA G++ + V++ T+FGL+V YD + V VTVP +Y +CGLCGNYN
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857
+ DD +P+ AG++ + G +W+ +P+S P C G PS + +
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWK--LPES---SEPGC--FLVGGKPSSCQENSMADAW 1738
Query: 3858 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 3917
K C +L +P GP S CH++V PQ C+ C G+ + LC ++ AY S C A
Sbjct: 1739 NKN--CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLC-AQ 1795
Query: 3918 GGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQCDSGFL 3975
G WRN TFCPM CP S Y C+ C CS+++ P CP CAE C+C G +
Sbjct: 1796 AGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHI 1855
Query: 3976 YNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQ 4033
+G +CVP+ QCGC Y P E+ + C + CTC V + C + +CKP Q+C
Sbjct: 1856 LSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICW 1915
Query: 4034 PSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDF 4093
G+L C G GV C L G+ HY SFDG
Sbjct: 1916 ALDGLLRC------------------RASGVGV--------CQLPGESHYVSFDGSNHSI 1949
Query: 4094 QGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NRGNPAVSYVRVVTVAALGTNISIHKDE 4152
C VL P ++ L F ++ K++ G + V + +++ K
Sbjct: 1950 PDACTLVLVKVCHPAMA---LPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH 2006
Query: 4153 IGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGA 4212
+V +N LP +SV + +++ G+QV +D N +++ +P++Y+G
Sbjct: 2007 --RVLINSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGK 2064
Query: 4213 VCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLC--------------WDE 4258
VCG+CGN + ++ + P+ +A S + SW+ DP C +
Sbjct: 2065 VCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQEN 2124
Query: 4259 CRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 4318
G+C R + P+ + C + + F C +C GG
Sbjct: 2125 PSGNCRAADLRRAREKCEAALRAPV-------WAQCASRIDLTPFLVDCANTLCEFGGLY 2177
Query: 4319 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 4378
LC+AL ++ A CQ+ G+ WR C + CP S Y C P C SC
Sbjct: 2178 QALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEG 2237
Query: 4379 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 4437
A C EGC C G+VLS D+CVP + CGC A+G G W C++ C C
Sbjct: 2238 AKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAHGGSIPLGKS-WVSSGCTEKCVC- 2294
Query: 4438 PGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 4496
GG++ C C G C L + C + +C +GDP Y+T DG + QG
Sbjct: 2295 -TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
Query: 4497 EYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Y+L P G E V N+ ++ + + V +Y + + L A +L V+
Sbjct: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQA--GLELVVN 2411
Query: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
+A+P++ + L L G + + T L ++F G + +P+ Y + GLCGNY
Sbjct: 2412 NQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNY 2471
Query: 4617 NQDPADDLKAVGGKPA--------GWQV--------------GGAQGCGECVSKPC---P 4651
+++ +D+ G W+V +G G +
Sbjct: 2472 DKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQV 2531
Query: 4652 SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG---HPGGL 4708
S C+PEQ S AC V++ GP A CH V P + + C+LD C Q
Sbjct: 2532 SECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELR 2590
Query: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQC 4739
C ++ Y CQ AGA L WR C C
Sbjct: 2591 CQVLSGYAILCQEAGAALAGWRDRTLCESPC 2621
Score = 851 bits (2198), Expect = 0.0
Identities = 548/1698 (32%), Positives = 779/1698 (45%), Gaps = 138/1698 (8%)
Query: 2336 QCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 2395
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCKS--PRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 2396 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVA-VGSTTCQ 2454
+ YY G ++ P C CRC G V C+ S CG H C+ G GC G+ TC
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
Query: 2455 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 2514
GDPHY TFDGR F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYV 1216
Query: 2515 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 2574
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D
Sbjct: 1217 TLPESTVTLLKGR-RTLVGGQQVTLPAIPSKGVFLGAS-GRFVELQTEFGLRVRWDGDQQ 1274
Query: 2575 VRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPP 2633
+ VTV Y +CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQ 1334
Query: 2634 TCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 2693
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 1335 V--------VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMC 1386
Query: 2694 LGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSAL 2753
G +LC+++ + CQ AG V+PWR FCPM CP NS Y LCA C C +
Sbjct: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
Query: 2754 SAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHN-GAYYEPEQTVLIDNCRQQCTC 2812
+ + C D C E C+C+ GF+ +G C+P QCGC H G+Y++ + C++ C C
Sbjct: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC 1506
Query: 2813 HVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 2872
+ CQ C R QE C +Q G C A
Sbjct: 1507 ESNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAA 1540
Query: 2873 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPA-VS 2931
TC GDPHY +FDG F GTC YVL P S + F V+ N+NRG VS
Sbjct: 1541 TCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVS 1597
Query: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 2991
Y++ V V +IS+ + KV +NG ALPV +A GR+++ ++ LL +FGLQ
Sbjct: 1598 YIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
Query: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GW 3050
V YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESS 1715
Query: 3051 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110
+P C+ G +C E+ + + P GPF+ CH VPP+S F CV
Sbjct: 1716 EPGCF-LVGGKPSSCQENSMADAWNKNCAILINPQ--GPFSQCHQVVPPQSSFASCVHGQ 1772
Query: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 3170
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C S
Sbjct: 1773 CGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS 1831
Query: 3171 PAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADG 3227
+ P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 1832 ---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTEN 1887
Query: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 3287
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 1888 TCTRLCTCSVHN-NITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDGS 1945
Query: 3288 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLSA 3346
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 1946 NHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQK 2004
Query: 3347 RWPRKLQVDGVFVTLPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAAY 3404
++ ++ VTLP + + + + + +V G+ + FDG+ + + +P Y
Sbjct: 2005 G--HRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
Query: 3405 AGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP--------- 3455
G +CG+CGN+N + D+L + A ++ K C
Sbjct: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQIP 2118
Query: 3456 -EQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHPG 3505
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 2119 AEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
Query: 3506 GLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAP-EGC 3564
LC A+ + A CQ+ G + WR FCP +CPA+S Y C SC SC L EG
Sbjct: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGA 2238
Query: 3565 E--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DDRYYPLGQTFYPGPGCDSLCRCREG 3621
+ SAC EGC+C G+VLS D CVP QCGC PLG+++ GC C C G
Sbjct: 2239 KVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSS-GCTEKCVCT-G 2296
Query: 3622 GEVSCEPSSC--GPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYV 3679
G + C C G H + CV+ S C GDP Y TFDG + G YV
Sbjct: 2297 GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYV 2356
Query: 3680 LAQTCGTRP-GLHRFAVLQEN-VAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 3737
L +T P G+ V N + + + VIT V + ++L Q ++ VN
Sbjct: 2357 LIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITT-VYGYKVQL-QAGLELVVNNQK 2414
Query: 3738 MKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG 3797
M +P N +R + G + + TDF L V++ +++P Y L+ GLCGNY+
Sbjct: 2415 MAVPY-RPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDK 2473
Query: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGC---------IPSDK 3848
+ K+D P+G+ N N FGNSWE D+ P P G + +
Sbjct: 2474 NRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSE 2533
Query: 3849 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG---NLSILCS 3905
C PE + + C +L+ P GP ++CH+ V P+ + C+ DLC + C
Sbjct: 2534 CSPE-QLASNSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQ 2592
Query: 3906 NIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD-GC 3964
+ Y CQ AG + WR+ T C C QN C + QC + G
Sbjct: 2593 VLSGYAILCQEAGAALAGWRDRTLCESPCLQNP----CQNDG-----------QCREQGA 2637
Query: 3965 AEGCQCDSGFLYNGQACV 3982
C+C+ G Y G C+
Sbjct: 2638 TFTCECEVG--YGGGLCM 2653
Score = 846 bits (2185), Expect = 0.0
Identities = 535/1646 (32%), Positives = 768/1646 (46%), Gaps = 128/1646 (7%)
Query: 3537 QCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 3596
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 3597 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGC-VAVGSTTCQ 3655
+ YY G ++ P C CRC G V C+ S CG H C+ G GC G+ TC
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGCHPYAGTATCL 1157
Query: 3656 ASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 3715
GDPHY TFDG F FMG C Y+LAQ CG F V +N G VS + V
Sbjct: 1158 VYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPF-FRVTAKNEEQGQEGVSCLSKVYV 1216
Query: 3716 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 3775
+ T+ L + + + V G + LP + + G + G V ++T+FGLRV +D
Sbjct: 1217 TLPESTVTLLKGR-RTLVGGQQVTLPAIPSKG-VFLGASGRFVELQTEFGLRVRWDGDQQ 1274
Query: 3776 VRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWE-EVVPDSPCLPPP 3834
+ VTV Y +CGLCGNY+G+ +D K +GS AG+ E GNSW+ + D C
Sbjct: 1275 LYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQEC---- 1330
Query: 3835 TCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 3894
+ S C L+ FCG L GP +C V C+ D+C
Sbjct: 1331 ----QKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMC 1386
Query: 3895 LGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSAL 3954
G +LC+++ + CQ AG V+PWR FCPM CP NS Y LCA C C +
Sbjct: 1387 GFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSG 1446
Query: 3955 SAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTC 4013
+ + C D C E C+C+ GF+ +G C+P QCGC H G Y++ + C++ C C
Sbjct: 1447 FSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVC 1506
Query: 4014 HVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 4073
+ CQ C R QE C +Q G C A
Sbjct: 1507 ESNNRIRCQPWRC--------------------------RAQEFCGQQDGIYGCHAQGAA 1540
Query: 4074 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGN-PAVS 4132
TC GDPHY +FDG F GTC YVL P S + F V+ N+NRG VS
Sbjct: 1541 TCTASGDPHYLTFDGALHHFMGTCTYVLTR---PCWSRSQDSYFVVSATNENRGGILEVS 1597
Query: 4133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 4192
Y++ V V +IS+ + KV +NG ALPV +A GR+++ ++ LL +FGLQ
Sbjct: 1598 YIKAVHVTVFDLSISLLRG--CKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQ 1655
Query: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GW 4251
V YD + V+VT+PSSY G +CGLCGN + N +D + P+ LA G +W+ P
Sbjct: 1656 VRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESS 1715
Query: 4252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311
+P C+ G +C E+ + C L + GPF+ CH VPP+S F CV
Sbjct: 1716 EPGCF-LVGGKPSSCQENSMADAWNKN-CAILIN-PQGPFSQCHQVVPPQSSFASCVHGQ 1772
Query: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371
C GD LC++L +Y + C AG WR + C + CP S Y C PCP +C S
Sbjct: 1773 CGTKGDTTALCRSLQAYASLCAQAGQA-PAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS 1831
Query: 4372 PAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADG 4428
+ P C PC E C+C G +LS CVPL CGC G+YH G ++ +
Sbjct: 1832 ---INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQ-CGCTDPAGSYHPVGERWYTEN 1887
Query: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 4488
TC++ C C ++ C ++C ++C L G C+ CQ G+ HYV+ DG
Sbjct: 1888 TCTRLCTCSV-HNNITCFQSTCKPNQICWAL-DGLLRCRASGVGVCQLPGESHYVSFDGS 1945
Query: 4489 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANE-HRGSQAVSYTRSVTLQIYNHSLTLSA 4547
C +L CH P + F ++ +E G V + IY+ +TL
Sbjct: 1946 NHSIPDACTLVLVKVCH-PAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQK 2004
Query: 4548 RWPRKLQVDGVFVALPFQLDSLLHAHLSGADV--VVTTTSGLSLAFDGDSFVRLRVPAAY 4605
++ ++ V LP + + + + + +V G+ + FDG+ + + +P Y
Sbjct: 2005 --GHRVLINSKQVTLP-AISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTY 2061
Query: 4606 AASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPC----------T 4655
+CG+CGN+N + D+L + A ++ K C
Sbjct: 2062 YGKVCGMCGNFNDEEEDELMMPSDEVAN---SDSEFVNSWKDKDIDPSCQSLLVDEQQIP 2118
Query: 4656 PEQQESFGGPDACGVI--------SATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHPG 4706
EQQE+ G + +A P+ A C + + C C+ G
Sbjct: 2119 AEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQ 2178
Query: 4707 GLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGC 4765
LC A+ + A CQ+ G + WR FCPL+CPA+S Y C SC SC L EG
Sbjct: 2179 ALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGA 2238
Query: 4766 E--SACREGCVCDAGFVLSGDTCVPVGQCGCLH-DGRYYPLGEVFYPGPECERRCECGPG 4822
+ SAC EGC+C G+VLS D CVP QCGC G PLG+ + C +C C G
Sbjct: 2239 KVPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGK-SWVSSGCTEKCVC-TG 2296
Query: 4823 GHVTCQE-GAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 4881
G + C + G H + ++ C + +C G Y+T DG Y L G +YV
Sbjct: 2297 GAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYV 2356
Query: 4882 LAQVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAVA 4935
L + P + +V +N LQ ++ TV G V L G ++ V+ + +A
Sbjct: 2357 LIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMA 2416
Query: 4936 LPVAVG-RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 4994
+P +RVT G+ + L T L + F G + ++S+PS + G + GLCGN++ N
Sbjct: 2417 VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRK 2476
Query: 4995 DDFVLPNGSAASSVETFGAAWRA-------------PGSSKGCGEGCGPQ-GCPV--CLA 5038
+D +LP+G+ ++ TFG +W P +G G G + G V C
Sbjct: 2477 NDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSP 2536
Query: 5039 EETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLA 5095
E+ A S +AC L +PQGPFA C ++P + CV DLC+ + + C+ L+
Sbjct: 2537 EQLAS-NSTQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLS 2595
Query: 5096 AYTAACQAAGVAVKPWRTDSFCPLHC 5121
Y CQ AG A+ WR + C C
Sbjct: 2596 GYAILCQEAGAALAGWRDRTLCESPC 2621
Score = 835 bits (2157), Expect = 0.0
Identities = 544/1722 (31%), Positives = 780/1722 (45%), Gaps = 139/1722 (8%)
Query: 718 LSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCV 777
+S +A + + +G + + CP N+RYE C ACP SC +P G C
Sbjct: 1017 MSPHAPSTPMTSVILGTTTTSRSSTERCPPNARYESC--ACPASCK---SPRPSCGPLCR 1071
Query: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
EGCVC PGF+ S C+ ASSC C + PG E W C C C + +V C+
Sbjct: 1072 EGCVCNPGFLFSDNHCIQASSCNCFYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQI 1129
Query: 838 KQSCPAGERCSVQNGLLGCYP-DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQ 896
Q C C ++NG GC+P TC GDPHYV+FDGR F FMG CTY+L CG
Sbjct: 1130 SQ-CGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCG- 1187
Query: 897 NAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAA 956
N+ P FRV +NE +G + VS V V V + + + LV LP +
Sbjct: 1188 NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLK--GRRTLVGGQQVTLPAIPS 1245
Query: 957 DGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLAL 1016
G V + GR ++T+FGL V +D + ++ V S+Y+ LCGLCGN++G+ +D
Sbjct: 1246 KG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLK 1304
Query: 1017 RGGGQAANALAFGNSWQ--EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
G A + GNSWQ ++ C + + P DS + + CG L D GP
Sbjct: 1305 LDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTHGP 1364
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
F C + C+ D C G LC ++T CQ AG V PWR CP+
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVH- 1193
+CPP+S Y C+ CP +C C C E C C+ GF LSG C+P + CGC+H
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGFSGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHP 1484
Query: 1194 QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQ 1253
G+Y G+ +Y PGC LC C+ + C+ C E C G GC A G++TC
Sbjct: 1485 AGSYFKVGERWYK-PGCKELCVCESNNRIRCQPWRCRAQEFCGQQDGIYGCHAQGAATCT 1543
Query: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
ASGDPHY TFDG FMGTC YVL + C +R F V N G G + V+ + V
Sbjct: 1544 ASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRG-GILEVSYIKAV 1602
Query: 1314 QVANFTLRLE-QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVY 1372
V F L + R KV +NG + LPV LA G++ + V++ T+FGL+V YD +
Sbjct: 1603 HVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSH 1662
Query: 1373 YVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT 1432
V VTVP +Y Q+CGLCGNYN + DD +P+ AG++ + G +W+ +P+S
Sbjct: 1663 LVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWK--LPES------ 1714
Query: 1433 PCPPGSEDCIPSHKCPPELEKKYQKEEF---CGLLSSPTGPLSSCHKLVDPQGPLKDCIF 1489
PG C P ++ + + C +L +P GP S CH++V PQ C+
Sbjct: 1715 -SEPG---CFLVGGKPSSCQENSMADAWNKNCAILINPQGPFSQCHQVVPPQSSFASCVH 1770
Query: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
C G+ + LC ++ AY S C A G WR TFCPM CPP S Y C+ C C
Sbjct: 1771 GQCGTKGDTTALCRSLQAYASLC-AQAGQAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTC 1829
Query: 1550 SALSAPPQCQDG--CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEP--EQTVLIDNC 1605
S+++ P C CAE C+C G + +G +CVP+ QCGC Y P E+ + C
Sbjct: 1830 SSINNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTC 1889
Query: 1606 RQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
+ CTC + C + +CKP Q+C G+L C G GV
Sbjct: 1890 TRLCTCSVHNNITCFQSTCKPNQICWALDGLLRC------------------RASGVGV- 1930
Query: 1666 LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ-NR 1724
C L G+ HY SFDG C VL P ++ L F ++ K++
Sbjct: 1931 -------CQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAMA---LPFFKISAKHEKEE 1980
Query: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 1784
G + V + +++ K +V +N LP +SV + +++
Sbjct: 1981 GGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPAISQIPGVSVKSSSIYSIVN 2038
Query: 1785 ADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 1844
G+QV +D N +++ +P++Y+G VCG+CGN + ++ + P+ +A S + SW
Sbjct: 2039 IKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNSW 2098
Query: 1845 RAPGWDPLCWDECRGSCPTCPEDRLEQYEGP-GFCGPL----------APGTGGPFTTCH 1893
+ DP C+ + EQ E P G C A + C
Sbjct: 2099 KDKDIDP----SCQSLLVDEQQIPAEQQENPSGNCRAADLRRAREKCEAALRAPVWAQCA 2154
Query: 1894 AHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 1953
+ + F C +C GG LC+AL ++ A CQ+ G+ WR C + CP
Sbjct: 2155 SRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAY 2214
Query: 1954 SHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW-AN 2012
S Y C C SC A C EGC C G+VLS D+CVP + CGC A+
Sbjct: 2215 SSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEGCICQPGYVLSEDKCVP-RSQCGCKDAH 2273
Query: 2013 GTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH-GCQPVSTAE 2071
G G W C++ C C GG++ C C G C L + C + +
Sbjct: 2274 GGSIPLGKS-WVSSGCTEKCVC--TGGAIQCGDFRCPSGSHCQLTSDNSNSNCVSDKSEQ 2330
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131
C +GDP Y+T DG + QG Y+L P G E V N+ ++ + +
Sbjct: 2331 CSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQE 2390
Query: 2132 VTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
V +Y + + L A +L V+ + +P++ + L L G + + T L ++F G
Sbjct: 2391 VITTVYGYKVQLQA--GLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTDFELVVSFGG 2448
Query: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQV--------- 2234
+ +P+ Y G + GLCGNY+++ +D+ G W+V
Sbjct: 2449 RKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRF 2508
Query: 2235 -----GGAQGCGECVSKPC---PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 2286
+G G + S C+PEQ S AC V++ GP A CH V P
Sbjct: 2509 PRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQTVAPE 2567
Query: 2287 QYFQGCLLDACQVQG---HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHY 2343
+ + C+LD C Q C ++ Y CQ AGA L WR C C +
Sbjct: 2568 PFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQNP-- 2625
Query: 2344 ELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCV 2385
C + G C A CE C+ G+ G C+
Sbjct: 2626 --CQND--GQCREQGATFTCE--------CEVGY--GGGLCM 2653
Score = 834 bits (2154), Expect = 0.0
Identities = 536/1669 (32%), Positives = 759/1669 (45%), Gaps = 134/1669 (8%)
Query: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 2792
CP N+ YE CA C C S C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 2793 AYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCR 2852
YYEP NC + C C G V CQ C VCQ G C P G
Sbjct: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
Query: 2853 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 2912
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
Query: 2913 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 2972
F VT KN+ +G VS + V V + +++ K + V G LP + G
Sbjct: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKG- 1247
Query: 2973 ISVTQGASKAL--LVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
V GAS L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND +
Sbjct: 1248 --VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKL 1305
Query: 3031 NGTLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGP 3089
+G+ A G SW+ D C + P+C GPGFCG L T GP
Sbjct: 1306 DGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGP 1364
Query: 3090 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 3149
F TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C +
Sbjct: 1365 FETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPM 1424
Query: 3150 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG 3209
CP NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CG
Sbjct: 1425 ACPPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CG 1480
Query: 3210 CW-ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV 3268
C G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 1481 CLHPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQ 1537
Query: 3269 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAV 3327
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG V
Sbjct: 1538 GAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEV 1596
Query: 3328 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTTTSGL 3386
SY ++V + +++ S++L K+ ++G V LP L + LS V++ T GL
Sbjct: 1597 SYIKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGL 1654
Query: 3387 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGEC 3444
+ +DG V + VP++Y G LCGLCGNYN + DD K AG Q+G A E
Sbjct: 1655 QVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPES 1714
Query: 3445 VSKPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 3498
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 1715 SEPGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 3499 QVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSL 3558
+G LC ++ Y + C AG Q WR FCP +CP S Y C CP +C S+
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 3559 SAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-DRYYPLGQTFYPGPGCDSL 3615
+ P C A C E C C G +LSG +CVP+GQCGC Y+P+G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 3616 CRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGT 3675
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 3676 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLE-QRQWKVTVN 3734
C VL + C L F + ++ G R+ V + + ++ Q+ +V +N
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEK-EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLIN 2011
Query: 3735 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 3794
+ LP + + ++ G++V +D + + + +P YY +CG+CGN
Sbjct: 2012 SKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGN 2071
Query: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPPTCPPGSAGCIPSDKC-P 3850
+N + +D+ P+ A + +EF NSW++ D C L P PS C
Sbjct: 2072 FNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNCRA 2131
Query: 3851 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 3910
+L + +K E L +P + C +D L DC LC GG LC + A+
Sbjct: 2132 ADLRRAREKCE--AALRAPVW--AQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAF 2187
Query: 3911 VSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ---CPDGCAEG 3967
+ CQ+ G WRN +FCP+ECP S Y C +CS C L + P CAEG
Sbjct: 2188 GATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPSACAEG 2247
Query: 3968 CQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 4026
C C G++ + CVP QCGC +G ++ + C ++C C G + C + C
Sbjct: 2248 CICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCGDFRC 2306
Query: 4027 KPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSF 4086
G CQ +T D C+ + C ++GDP Y +F
Sbjct: 2307 PSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPRYLTF 2342
Query: 4087 DGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNI 4146
DG + QG YVL T V +G+ P V +N+ + +++ V G +
Sbjct: 2343 DGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKV 2400
Query: 4147 SIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLP 4206
+ ++ VN A+P + + V + LV DF L VS+ ++LP
Sbjct: 2401 QLQAGL--ELVVNNQKMAVPYRPNE-HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLP 2457
Query: 4207 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL--------CWDE 4258
S Y G V GLCGN D+N ND + P+G L ++ +G SW D L +E
Sbjct: 2458 SMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEE 2517
Query: 4259 CRGS---------CPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVL 4309
+G+ C ++L C L+ G PF CH V PE F + CVL
Sbjct: 2518 GQGAELGLRTGLQVSECSPEQLASNSTQA-CRVLADPQG-PFAACHQTVAPEPFQEHCVL 2575
Query: 4310 DVCMGGGDRD---ILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 4355
D+C R+ + C+ L+ Y CQ AG + WR + CE C +N
Sbjct: 2576 DLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQN 2624
Score = 813 bits (2100), Expect = 0.0
Identities = 516/1598 (32%), Positives = 741/1598 (46%), Gaps = 125/1598 (7%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAES-TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
C+ QC CQ+ G+ GC + TA C GDPHY TFDGR + MG C+Y + + C
Sbjct: 1127 CQISQCGTHTVCQLKNGQYGCHPYAGTATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPC 1186
Query: 503 SEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVS 562
+ T P F V AKNE +G VS + V V +V+L +G LV Q+ LP
Sbjct: 1187 G-NSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRR--TLVGGQQVTLPAI 1243
Query: 563 LSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDF 622
S+G + + SG ++ FGL V +D D QL +++ + + ++CGLCGNY+G+ +D
Sbjct: 1244 PSKG-VFLGASGRFVELQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDH 1302
Query: 623 LTPDGALAPDAVEFASSWKLD-DGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
L DG+ A D E +SW+ D D D C+ N P+C G CG L
Sbjct: 1303 LKLDGSPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVDTH 1362
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
GPF C + F + C+ D+C G + LC +S C + G +V WR P C
Sbjct: 1363 GPFETCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFC 1422
Query: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
P++CP NS+Y LC CP +C+ + CS R CVE C C PGFV SG C+P S CGC
Sbjct: 1423 PMACPPNSKYSLCAKPCPDTCHSGFSGMFCSDR-CVEACECNPGFVLSGLECIPRSQCGC 1481
Query: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
E W C+ C C + +++ C+ + C A E C Q+G+ GC+
Sbjct: 1482 LHPAGSYFKVGERWYKPGCKELCVCE-SNNRIRCQPWR-CRAQEFCGQQDGIYGCHAQGA 1539
Query: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS-QTVSYT 920
TC SGDPHY++FDG FMGTCTY+L C + F V NE+RG VSY
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSYFVVSATNENRGGILEVSYI 1599
Query: 921 RAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVT 980
+AV V + +++ R +V+++ LP A G+V + ++ T+FGL V
Sbjct: 1600 KAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVR 1657
Query: 981 YDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRP 1038
YD + V VPSSY LCGLCGN+N + DD A +++ G +W+ E + P
Sbjct: 1658 YDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEP 1717
Query: 1039 GCGAT--EPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
GC +P C + A +KN C IL +P+GPF +CH + PQ + CV+ +C
Sbjct: 1718 GCFLVGGKPSSCQENSMADA---WNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQC 1773
Query: 1097 LLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDL 1156
G + LC +L YA+ C AG WR+ CP+ CPP S Y CS CP +C +
Sbjct: 1774 GTKGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSI 1832
Query: 1157 PVPGGC--GSECHEGCVCDEGFALSGESCLPLASCGCVH-QGTYHPPGQTFYPGPGCDSL 1213
P C C E C C +G LSG SC+PL CGC G+YHP G+ +Y C L
Sbjct: 1833 NNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRL 1892
Query: 1214 CHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGT 1273
C C ++C S+C P++ C G L C A G CQ G+ HY +FDG
Sbjct: 1893 CTCSVHNNITCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDA 1952
Query: 1274 CVYVLAQTCGTRPGLHRFAV--LQENVAWGNGRVSVTRV-ITVQVANFTLRLEQRQWKVT 1330
C VL + C L F + E G + V I + A TL Q+ +V
Sbjct: 1953 CTLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTL---QKGHRVL 2009
Query: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLC 1390
+N + LP + + ++ G++V +D + + + +P YY ++CG+C
Sbjct: 2010 INSKQVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMC 2069
Query: 1391 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC---LPPTPCPPGSEDCIPSHKC 1447
GN+N + +D+ P+ A + +EF NSW++ D C L P + PS C
Sbjct: 2070 GNFNDEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPAEQQENPSGNC 2129
Query: 1448 -PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 1506
+L + +K E L +P + C +D L DC LC GG LC +
Sbjct: 2130 RAADLRRAREKCE--AALRAPV--WAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQ 2185
Query: 1507 AYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQ-----DG 1561
A+ + CQ+ G WR +FCP+ECP S Y C +CS C L +C+
Sbjct: 2186 AFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDG--RCEGAKVPSA 2243
Query: 1562 CAEGCQCDSGFLYNGQACVPIQQCGCYH-NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
CAEGC C G++ + CVP QCGC +G ++ + C ++C C G + C
Sbjct: 2244 CAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVC-TGGAIQCG 2302
Query: 1621 EHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPH 1680
+ C G CQ +T D C+ + C ++GDP
Sbjct: 2303 DFRCPSGSHCQ--------LTSD----------------NSNSNCVSDKSEQCSVYGDPR 2338
Query: 1681 YHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
Y +FDG + QG YVL T V +G+ P V +N+ + +++ V
Sbjct: 2339 YLTFDGFSYRLQGRMTYVLIKT--VDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVY 2396
Query: 1741 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 1800
G + + ++ VN A+P + + VT + LV DF L VS+
Sbjct: 2397 GYKVQLQAGL--ELVVNNQKMAVPYR-PNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAV 2453
Query: 1801 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL-------- 1852
++LPS Y G V GLCGN D+N ND + P+G L ++ +G SW D L
Sbjct: 2454 ISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQNLNTFGNSWEVKTEDALLRFPRAIP 2513
Query: 1853 CWDECRGS---------CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFK 1903
+E +G+ C ++L C LA GPF CH V PE F +
Sbjct: 2514 AEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLA-DPQGPFAACHQTVAPEPFQE 2571
Query: 1904 GCVLDVCMGGGDR---DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCG 1960
CVLD+C R ++ C+ L+ Y CQ AG + WR + CE
Sbjct: 2572 HCVLDLCSAQDPREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCE------------- 2618
Query: 1961 SPCPASCPSPAPLTTPAVCEGPCVE-----GCQCDAGF 1993
SPC L P +G C E C+C+ G+
Sbjct: 2619 SPC---------LQNPCQNDGQCREQGATFTCECEVGY 2647
Score = 745 bits (1923), Expect = 0.0
Identities = 483/1508 (32%), Positives = 696/1508 (46%), Gaps = 132/1508 (8%)
Query: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 3993
CP N+ YE CA C C S C C EGC C+ GFL++ C+ C C++N
Sbjct: 1044 CPPNARYESCA--CPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYNN 1099
Query: 3994 VYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCR 4053
YYEP NC + C C G V CQ C VCQ G C P G
Sbjct: 1100 DYYEPGAEWFSPNCTEHCRCWPGSRVECQISQCGTHTVCQLKNGQYGC---HPYAGT--- 1153
Query: 4054 PQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQG 4113
ATC ++GDPHY +FDGR F F G C Y+LA C G ST
Sbjct: 1154 -------------------ATCLVYGDPHYVTFDGRHFGFMGKCTYILAQP-C-GNSTDP 1192
Query: 4114 LTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGR 4173
F VT KN+ +G VS + V V + +++ K + V G LP + G
Sbjct: 1193 F--FRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGR--RTLVGGQQVTLPAIPSKGV 1248
Query: 4174 ISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
A G L +FGL+V +D + ++ VT+ S+Y G +CGLCGN D N +ND + +G
Sbjct: 1249 FLGASGRFVELQT-EFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDG 1307
Query: 4234 TLAPSIPIWGGSWRAP-GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFT 4292
+ A G SW+ D C + P+C GPGFCG L T GPF
Sbjct: 1308 SPAGDKEELGNSWQTDQDEDQECQKYQVVNSPSCDSSLQSSMSGPGFCGRLVD-THGPFE 1366
Query: 4293 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 4352
TC HV SFF C+LD+C G + +LC +++ CQ AG ++ WR C + C
Sbjct: 1367 TCLLHVKAASFFDSCMLDMCGFQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMAC 1426
Query: 4353 PENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCW 4412
P NS Y +C PCP +C S + C CVE C+C+ GFVLS C+P + CGC
Sbjct: 1427 PPNSKYSLCAKPCPDTCHSGF---SGMFCSDRCVEACECNPGFVLSGLECIPRSQ-CGCL 1482
Query: 4413 -ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST 4471
G+Y + G ++ G C + C C + C P C E CG G +GC
Sbjct: 1483 HPAGSYFKVGERWYKPG-CKELCVC-ESNNRIRCQPWRCRAQEFCGQ-QDGIYGCHAQGA 1539
Query: 4472 AECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSY 4530
A C A GDPHY+T DG F GTC Y+L+ PC + F V+ NE+RG VSY
Sbjct: 1540 ATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDSY-FVVSATNENRGGILEVSY 1598
Query: 4531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSL 4589
++V + +++ S++L K+ ++G VALP L + LS V++ T GL +
Sbjct: 1599 IKAVHVTVFDLSISLLRGC--KVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQV 1656
Query: 4590 AFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--WQVGGAQGCGECVS 4647
+DG V + VP++Y LCGLCGNYN + DD K AG Q+G A E
Sbjct: 1657 RYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSE 1716
Query: 4648 KPC------PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQV 4701
C PS C + C ++ GP + CH +VPP F C+ C
Sbjct: 1717 PGCFLVGGKPSSCQENSMADAWNKN-CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGT 1775
Query: 4702 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 4761
+G LC ++ Y + C AG Q WR FCP++CP S Y C CP +C S++
Sbjct: 1776 KGDTTALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINN 1834
Query: 4762 PEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCE 4818
P C A C E C C G +LSG +CVP+GQCGC G Y+P+GE +Y C R C
Sbjct: 1835 PRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCT 1894
Query: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 4878
C ++TC + + C P++ C DG+ C A+G G C G HY++ DG + + +C
Sbjct: 1895 CSVHNNITCFQ-STCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDAC 1953
Query: 4879 SYVLAQVCHPKPGDEDFSIVL--EKNAAGD----LQRLLVTVAGQVVSLAQGQQVTVDGE 4932
+ VL +VCHP F I EK G L + + + V+L +G +V ++ +
Sbjct: 1954 TLVLVKVCHPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSK 2013
Query: 4933 AVALPVA--VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFN 4990
V LP + V V + ++ G+++ FDG+ L + IP+ + G++CG+CGNFN
Sbjct: 2014 QVTLPAISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFN 2073
Query: 4991 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 5050
D+ ++P+ A+S F +W+ C + + E+ P E E
Sbjct: 2074 DEEEDELMMPSDEVANSDSEFVNSWKDKDIDPSCQS--------LLVDEQQIPAEQQE-- 2123
Query: 5051 GQLRNPQGP---------------------FATCQAVLSPSEYFRQCVYDLCAQKGDKAF 5089
NP G +A C + + + + C LC G
Sbjct: 2124 ----NPSGNCRAADLRRAREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQA 2179
Query: 5090 LCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL---TG 5146
LC++L A+ A CQ+ G+ WR SFCPL CPA+S Y+ C +C SC L G
Sbjct: 2180 LCQALQAFGATCQSQGLKPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAK 2239
Query: 5147 CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSG 5205
+ C EGC C ++LS+ C+P CGC +G +P+ S ++S C+E+C C+ +
Sbjct: 2240 VPSACAEGCICQPGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA- 2298
Query: 5206 LTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRC 5265
+ C CP G C++ ++ N CV + + R T Y L R
Sbjct: 2299 IQCGDFRCPSGSHCQLTSDNSN-----SNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRM 2353
Query: 5266 P-GLQNTIPWYRVVAEVQICHGKTEA-VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 5323
L T+ E + G+ + + IF Q+ + T+ K GL + + +
Sbjct: 2354 TYVLIKTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQ 2413
Query: 5324 KLASVSVSRTPDGSLLVR---------QKAGVQVWLGANGKVAVIVSNDHAGKLCGACGN 5374
K+A V P+ L V + V G + + + + G + G CGN
Sbjct: 2414 KMA---VPYRPNEHLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGN 2470
Query: 5375 FDGDQTND 5382
+D ++ ND
Sbjct: 2471 YDKNRKND 2478
Score = 646 bits (1667), Expect = 0.0
Identities = 392/1088 (36%), Positives = 549/1088 (50%), Gaps = 63/1088 (5%)
Query: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 4411
CP N+ YE C CPASC SP P P C EGC C+ GF+ S + C+ ++ C C
Sbjct: 1044 CPPNARYESCA--CPASCKSPRPSCGPL-----CREGCVCNPGFLFSDNHCIQASS-CNC 1095
Query: 4412 WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS- 4470
+ N Y+E G+E W C++ CRC PG + C + CG VC L +GQ+GC P +
Sbjct: 1096 FYNNDYYEPGAE-WFSPNCTEHCRCWPGS-RVECQISQCGTHTVCQL-KNGQYGCHPYAG 1152
Query: 4471 TAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSY 4530
TA C +GDPHYVT DG F F G C Y+L+ PC F VT NE +G + VS
Sbjct: 1153 TATCLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNST--DPFFRVTAKNEEQGQEGVSC 1210
Query: 4531 TRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLA 4590
V + + ++TL R+ V G V LP + SG V + T GL +
Sbjct: 1211 LSKVYVTLPESTVTLLKG--RRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVR 1268
Query: 4591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGA--Q 4640
+DGD + + V + Y+ LCGLCGNY+ + +D + G PAG WQ Q
Sbjct: 1269 WDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQ 1328
Query: 4641 GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ 4700
C + PS C Q S GP CG + T GP C V A +F C+LD C
Sbjct: 1329 ECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCG 1387
Query: 4701 VQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLS 4760
QG LC ++T CQ AG + WR P FCP+ CP +S Y LC CP +C S
Sbjct: 1388 FQGLQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGF 1447
Query: 4761 APEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPECERRCEC 4819
+ C C E C C+ GFVLSG C+P QCGCLH G Y+ +GE +Y P C+ C C
Sbjct: 1448 SGMFCSDRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYK-PGCKELCVC 1506
Query: 4820 GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCS 4879
+ CQ C E C +DG+ CHA G C A+G HY+T DG ++ G+C+
Sbjct: 1507 ESNNRIRCQPW-RCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCT 1565
Query: 4880 YVLAQVCHPKPGDEDFSI-VLEKNAAGDLQ-----RLLVTVAGQVVSLAQGQQVTVDGEA 4933
YVL + C + D F + +N G L+ + VTV +SL +G +V ++G
Sbjct: 1566 YVLTRPCWSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHR 1625
Query: 4934 VALPV--AVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNG 4991
VALPV A GRV + ++L T GL++ +DG + +++PS + G+LCGLCGN+N
Sbjct: 1626 VALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNN 1685
Query: 4992 NWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCG-EGCGPQGCPVCLAEETAPYESNEA 5049
N DD + P+ A GAAW+ P SS+ GC G P C E + N+
Sbjct: 1686 NSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSC----QENSMADAWNKN 1741
Query: 5050 CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVK 5109
C L NPQGPF+ C V+ P F CV+ C KGD LCRSL AY + C AG A
Sbjct: 1742 CAILINPQGPFSQCHQVVPPQSSFASCVHGQCGTKGDTTALCRSLQAYASLCAQAGQA-P 1800
Query: 5110 PWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGC--TTRCFEGCECDDRFLLSQGV 5167
WR +FCP+ CP S YS C+ C +C++++ C C E CEC +LS
Sbjct: 1801 AWRNRTFCPMRCPPGSSYSPCSSPCPDTCSSINNPRDCPKALPCAESCECQKGHILSGTS 1860
Query: 5168 CIPVQDCGCTH-NGRYLPVNSSLLTSD-CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEA 5225
C+P+ CGCT G Y PV T + C+ C+CS + +TC + C P ++C
Sbjct: 1861 CVPLGQCGCTDPAGSYHPVGERWYTENTCTRLCTCSVHNNITCFQSTCKPNQICWALDGL 1920
Query: 5226 RNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRC-PGLQNTIPWYRVVAEVQI 5283
C A+ G+C L ++ +FDG+ + L C P + +P++++ A+ +
Sbjct: 1921 LRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVCHPAM--ALPFFKISAKHEK 1978
Query: 5284 CHGKTEA--VGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPA-EKLASVSVSRTPDGSLLV 5340
G TEA + +V+I D VTL V +N +V LPA ++ VSV + S +V
Sbjct: 1979 EEGGTEAFRLHEVYIDIYDAQVTLQKGHRVLINSKQVTLPAISQIPGVSVKSSSIYS-IV 2037
Query: 5341 RQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPA------MEK 5394
K GVQV N + + + + GK+CG CGNF+ ++ ++ ++ A +
Sbjct: 2038 NIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDELMMPSDEVANSDSEFVNS 2097
Query: 5395 WRAQDFSP 5402
W+ +D P
Sbjct: 2098 WKDKDIDP 2105
Score = 376 bits (965), Expect = e-103
Identities = 221/659 (33%), Positives = 316/659 (47%), Gaps = 25/659 (3%)
Query: 4738 QCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHD 4797
+CP ++ YE C +CP SC S C CREGCVC+ GF+ S + C+ C C ++
Sbjct: 1043 RCPPNARYESC--ACPASCK--SPRPSCGPLCREGCVCNPGFLFSDNHCIQASSCNCFYN 1098
Query: 4798 GRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHA-TGCGRC 4856
YY G ++ P C C C PG V CQ + CG H C+L++G CH G C
Sbjct: 1099 NDYYEPGAEWF-SPNCTEHCRCWPGSRVECQI-SQCGTHTVCQLKNGQYGCHPYAGTATC 1156
Query: 4857 LANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLL 4911
L G HY+T DGR + G C+Y+LAQ C D F + + G L ++
Sbjct: 1157 LVYGDPHYVTFDGRHFGFMGKCTYILAQPC-GNSTDPFFRVTAKNEEQGQEGVSCLSKVY 1215
Query: 4912 VTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTKGLRLLFDGDAHL 4970
VT+ V+L +G++ V G+ V LP + V + A GR + LQT GLR+ +DGD L
Sbjct: 1216 VTLPESTVTLLKGRRTLVGGQQVTLPAIPSKGVFLGASGRFVELQTEFGLRVRWDGDQQL 1275
Query: 4971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 5030
+++ S + G+LCGLCGN++GN +D + +GS A E G +W+ +
Sbjct: 1276 YVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEELGNSWQTDQDEDQECQKYQV 1335
Query: 5031 QGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 5090
P C + + CG+L + GPF TC + + +F C+ D+C +G + L
Sbjct: 1336 VNSPSCDSSLQSSMSGPGFCGRLVDTHGPFETCLLHVKAASFFDSCMLDMCGFQGLQHLL 1395
Query: 5091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG--CT 5148
C ++ T CQ AG AVKPWR FCP+ CP +S YS+C + C +C SG +G C+
Sbjct: 1396 CTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCH--SGFSGMFCS 1453
Query: 5149 TRCFEGCECDDRFLLSQGVCIPVQDCGCTH-NGRYLPVNSSLLTSDCSERCSCSSSSGLT 5207
RC E CEC+ F+LS CIP CGC H G Y V C E C C S++ +
Sbjct: 1454 DRCVEACECNPGFVLSGLECIPRSQCGCLHPAGSYFKVGERWYKPGCKELCVCESNNRIR 1513
Query: 5208 CQAAGCPPGRVCEVKAEARNCWAT-RGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 5266
CQ C C + C A C S + TFDGA Y L+ C
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPC- 1572
Query: 5267 GLQNTIPWYRVVAEVQICHG---KTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAE 5323
+ Y VV+ G + + VH+ D ++L V +NG RV LP
Sbjct: 1573 -WSRSQDSYFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVW 1631
Query: 5324 KLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 5382
R +L+ G+QV + V V V + + G+LCG CGN++ + +D
Sbjct: 1632 LAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDD 1690
Score = 326 bits (836), Expect = 3e-88
Identities = 220/739 (29%), Positives = 330/739 (44%), Gaps = 64/739 (8%)
Query: 443 SCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELC 502
+C C Q C + G C A VC+ G+ HY +FDG + + C+ +V++C
Sbjct: 1902 TCFQSTCKPNQICWALDGLLRCRASGVGVCQLPGESHYVSFDGSNHSIPDACTLVLVKVC 1961
Query: 503 SEDDTLPAFSVEAKNE-HRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
LP F + AK+E G + V + Y V+L +G VL+++++ LP
Sbjct: 1962 HPAMALPFFKISAKHEKEEGGTEAFRLHEVYIDIYDAQVTLQKGH--RVLINSKQVTLPA 2019
Query: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
+ V S ++V + G+ V +D + L + +P + +VCG+CGN+N + D+
Sbjct: 2020 ISQIPGVSVKSSSIYSIVNIKIGVQVKFDGNHLLEIEIPTTYYGKVCGMCGNFNDEEEDE 2079
Query: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGC--QNNCPACTPGQAQHYEGDRLCGMLTK 679
+ P +A EF +SWK D D C+ + PA Q ++ G+ L +
Sbjct: 2080 LMMPSDEVANSDSEFVNSWKDKDIDPSCQSLLVDEQQIPA---EQQENPSGNCRAADLRR 2136
Query: 680 --------LDGP-FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGI 730
L P +A C +D PFL C LC GG +LC+ L A+ C G+
Sbjct: 2137 AREKCEAALRAPVWAQCASRIDLTPFLVDCANTLCEFGGLYQALCQALQAFGATCQSQGL 2196
Query: 731 SVGDWRSPANCPLSCPANSRYELCGPACPTS-------CNGAAAPSNCSGRPCVEGCVCL 783
WR+ + CPL CPA S Y C P+C S C GA PS C EGC+C
Sbjct: 2197 KPPLWRNSSFCPLECPAYSSYTNCLPSCSPSCWDLDGRCEGAKVPS-----ACAEGCICQ 2251
Query: 784 PGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
PG+V S CVP S CGC P + W C +C C G + C D + CP+
Sbjct: 2252 PGYVLSEDKCVPRSQCGCKDAHGGSIPLGKSWVSSGCTEKCVCTGGA--IQCGDFR-CPS 2308
Query: 844 GERCSV--QNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALP 901
G C + N C D+ C GDP Y++FDG + G TY+L+ + LP
Sbjct: 2309 GSHCQLTSDNSNSNCVSDKSEQCSVYGDPRYLTFDGFSYRLQGRMTYVLIKTVD---VLP 2365
Query: 902 --AFRVLVENEHRGSQTVS--YTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
+LVE ++ S + + V G KV ++ +++V++ +P++ +
Sbjct: 2366 EGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGL--ELVVNNQKMAVPYRPNE 2423
Query: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
++V G+ + TDF L V++ +PS Y + GLCGN++ + +D+ L
Sbjct: 2424 -HLRVTLWGQRLYLVTDFELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLP 2482
Query: 1018 GGGQAANALAFGNSWQEETRP-------GCGATEPGDCPKLDSLVAQQL----------Q 1060
G N FGNSW+ +T A E G +L Q+
Sbjct: 2483 SGALTQNLNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLASN 2542
Query: 1061 SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLL--PGQSGPL-CDALATYAAACQ 1117
S C +LADP+GPF CH + P+ CV D C P + L C L+ YA CQ
Sbjct: 2543 STQACRVLADPQGPFAACHQTVAPEPFQEHCVLDLCSAQDPREQEELRCQVLSGYAILCQ 2602
Query: 1118 AAGATVHPWRSEELCPLSC 1136
AGA + WR LC C
Sbjct: 2603 EAGAALAGWRDRTLCESPC 2621
>gi|134268640 tectorin alpha precursor [Homo sapiens]
Length = 2155
Score = 854 bits (2206), Expect = 0.0
Identities = 511/1621 (31%), Positives = 751/1621 (46%), Gaps = 101/1621 (6%)
Query: 781 VCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRD 837
V +PG F G PA+ GCT +G L G+ W D C +C C +++ C++
Sbjct: 239 VNVPGRWAFKVDGKEIDPAN--GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE 296
Query: 838 KQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQN 897
SC E C + C TC G+PHY +FDG F F G+C YLL C Q
Sbjct: 297 -ASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQT 355
Query: 898 AALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAAD 957
++LP F V +NEHR VS+ + + VE G K+ + + G+V V+D++ LP
Sbjct: 356 SSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDL 415
Query: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
G V++++ G V TDFGL VT+D + VP SY + CGLCGN+N +P DD
Sbjct: 416 GTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRP 475
Query: 1018 GGGQAANALAFGNSWQ-EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1076
G A + L G SW+ C + +C + D+ + CG L GP
Sbjct: 476 DGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLW 535
Query: 1077 ECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC--PL 1134
EC + +DP V CVYD C + LC A+ YA CQA G + WR++ C +
Sbjct: 536 ECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTV 595
Query: 1135 SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ 1194
CP SHY C+ CP +C DL C + C EGC C++GF LS C+PL CGC
Sbjct: 596 QCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFD 655
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQA 1254
G Y+ G+ F+ C C C+EGG V C + +CG E C G GC + C
Sbjct: 656 GHYYTMGEFFWATANCTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLL 715
Query: 1255 SGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQ 1314
S + TFDG + F Y L +TC RP + + N + + R + +
Sbjct: 716 SQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDINKKKPDAGPAWLRGLRIL 772
Query: 1315 VANFTLRLEQ-RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 1373
VA+ +++ +V +NG +++LP +G++ ++ + +E+ + V Y +
Sbjct: 773 VADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGL 832
Query: 1374 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLP 1430
+ + + Y+ GLCG YN + D+F PNG N F SW EE+
Sbjct: 833 LYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEI-------- 884
Query: 1431 PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPT-GPLSSCHKLVDPQGPLKDCIF 1489
C D + + EL K Y+ CG+++ P+ CH +V+ + C+F
Sbjct: 885 ---CNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLF 941
Query: 1490 DLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
LC GGN S LC ++ Y SAC+ A V PWRT FCP+ECP NSH+E C TC+ C
Sbjct: 942 RLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETC 1000
Query: 1550 SALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLID-NCRQQ 1608
L+ P C D C+EGCQCD G+ G CV +CGC G +T +D +C+
Sbjct: 1001 ETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIF 1060
Query: 1609 CTCHAGKGMV-CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLP 1667
C C V C+ CK + C GG+ C +
Sbjct: 1061 CYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQART------------------------ 1096
Query: 1668 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNP 1727
+A+C + G HY +FDG FDFQ +C +L TTG S+ F VT KN++R
Sbjct: 1097 --DASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTG-SRPSSDSFPKFVVTAKNEDRDPS 1153
Query: 1728 AVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF 1787
+V+ V V G +I IH+ V VN LP+ + G+I++ ++ DF
Sbjct: 1154 LALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDF 1213
Query: 1788 GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP 1847
GL+V YDW + +T+P S + GLCG + NP++D P G LA S+ +G SW
Sbjct: 1214 GLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKR 1273
Query: 1848 GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVL 1907
D C C CP+C ++E + L P F+ CH+ V P F+K C+
Sbjct: 1274 --DTFCQVGCGDRCPSCA--KVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLF 1329
Query: 1908 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASC 1967
D C+ GG C L +Y + CQ G+ + WR C +TCP NSHYE C S C C
Sbjct: 1330 DSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC 1389
Query: 1968 PSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGT 2027
A + + C CVEGC CDAG+VL+ C+ L + CGC+++G Y+E FW +
Sbjct: 1390 ---AAIRLKSDCSHYCVEGCHCDAGYVLNGKSCI-LPHSCGCYSDGKYYEPKQLFW-NSD 1444
Query: 2028 CSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHR 2087
C++ CRC + C P C E C L +G GC T+ C A G + T DG
Sbjct: 1445 CTRRCRCF-RRNVIQCDPRQCKSDEECA-LRNGVRGCFSTKTSYCLAAGGGVFRTFDGAF 1502
Query: 2088 FNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARW 2147
F C ++LS C P +F + + + + ++ V I + ++ R
Sbjct: 1503 LRFPANCAFVLSTICQKLP--DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDR- 1559
Query: 2148 PRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSL 2207
++V+G V +PF + S +V+ T+ + + ++G + +++ + +
Sbjct: 1560 -NTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKV 1618
Query: 2208 CGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ------GCGECVSKPCPSPCT 2253
CGLCGN+N D DD + GKP W+ G Q C E + C
Sbjct: 1619 CGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCD 1678
Query: 2254 PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
+ G C ++ G PC+GL+ P +++ C LD C LC ++A Y
Sbjct: 1679 NVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAY 1737
Query: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS-CPSLSAPEGCESACREGCV 2372
AC++ G EW + C + D C G+ CP+ + G RE C
Sbjct: 1738 GEACRSFGILSTEWIEKENCS---------GVVEDPCVGADCPNRTCELG---NGRELCG 1785
Query: 2373 C 2373
C
Sbjct: 1786 C 1786
Score = 850 bits (2197), Expect = 0.0
Identities = 506/1557 (32%), Positives = 740/1557 (47%), Gaps = 109/1557 (7%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
C+ C+ + C+ G C A T+ C G+PHY TFDG + G+C+Y + C
Sbjct: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL 353
Query: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 563
+ +LP FSVEAKNEHR VS+V ++V + + + +G G V V++ + LPV+L
Sbjct: 354 QTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTL 413
Query: 564 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
G +++YQSG VE FGL+VT+D ++S+P + + CGLCGNYN +P DDFL
Sbjct: 414 DLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFL 473
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
PDG A ++ SW++ D+ C+ GC +NC C Y G CG L K DGP
Sbjct: 474 RPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGP 533
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC-- 741
C +DP F+ CVYDLC V LC+ + AYA C LGI +GDWR+ C
Sbjct: 534 LWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVS 593
Query: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
+ CP+ S Y +C +CP +C+ A NC+ PC EGC C GFV S CVP CGC
Sbjct: 594 TVQCPSFSHYSVCTSSCPDTCSDLTASRNCA-TPCTEGCECNQGFVLSTSQCVPLHKCGC 652
Query: 802 TFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRF 861
F G G+ WA C +C C V C +K +C +GE C+V++G GC+P R
Sbjct: 653 DFDGHYYTMGEFFWATANCTVQCLCEEG-GDVYCFNK-TCGSGEVCAVEDGYQGCFPKRE 710
Query: 862 GTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTR 921
C S + +FDG + F +Y L+ +C + P + + N+ + ++ R
Sbjct: 711 TVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPER---PEYLEIDINKKKPDAGPAWLR 767
Query: 922 AVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
+R+ +V + +V ++ LPF G+++++R V + +TV Y
Sbjct: 768 GLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQY 827
Query: 982 DWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ--EETRPG 1039
+ ++ ++Y GLCG +N + +D+ L G N F SW EE G
Sbjct: 828 SDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEEICNG 887
Query: 1040 CGATEPGDCPKL---DSLVAQQLQSKNECGILADP-KGPFRECHSKLDPQGAVRDCVYDR 1095
E GD K DS + + +S++ CGI+ DP F ECH ++ R C++
Sbjct: 888 ----ECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRL 943
Query: 1096 CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1155
C G LCD++A YA+AC+ A V PWR+ + CPL CP +SH+E C C +C
Sbjct: 944 CQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITCTETCET 1002
Query: 1156 LPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1215
L + C C EGC CDEG+AL G C+ + CGC +G +TF+ C C+
Sbjct: 1003 LTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCY 1062
Query: 1216 CQ-EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1274
C V CE+ C E C GG C A ++C SG HY TFDG FDF +C
Sbjct: 1063 CSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSC 1122
Query: 1275 VYVLAQTCGTRP---GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR-QWKVT 1330
+L T G+RP +F V +N + + V V +++ + + + V
Sbjct: 1123 PLILC-TTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVL 1181
Query: 1331 VNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLC 1390
VN + LP+ L G+I G VV+ETDFGL+V YD ++ +TVP + GLC
Sbjct: 1182 VNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLC 1241
Query: 1391 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPE 1450
G YNG+P DD + P G A + NEFG SW + T C G D PS C +
Sbjct: 1242 GRYNGNPDDDLEMPMGLLASSVNEFGQSWVK--------RDTFCQVGCGDRCPS--C-AK 1290
Query: 1451 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVS 1510
+E + ++ C L+ + S CH V+P K+C+FD C+ GG + CS + Y S
Sbjct: 1291 VEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYAS 1350
Query: 1511 ACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDS 1570
CQ G V WR T C + CPPNSHYE C C C+A+ C C EGC CD+
Sbjct: 1351 TCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDA 1410
Query: 1571 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
G++ NG++C+ CGCY +G YYEP+Q +C ++C C + C CK + C
Sbjct: 1411 GYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEEC 1470
Query: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
G+ C + + C GG GV + +FDG
Sbjct: 1471 ALRNGVRGCFSTKTSY---------CLAAGG-GV----------------FRTFDGAFLR 1504
Query: 1691 FQGTCNYVLAT--TGCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIH 1747
F C +VL+T P +S Q + F + N +P Y+ + N
Sbjct: 1505 FPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN---- 1560
Query: 1748 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFG--LQVSYDWNWRVDVTLPS 1805
V+VNG +P ++ +S+ LV D +Q+ Y+ + +++
Sbjct: 1561 -----TVKVNGTQVNVPFITG---LATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISE 1612
Query: 1806 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 1865
VCGLCGN + + +D V G S + SW+ G + R P+C
Sbjct: 1613 RLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGM------QKRPLAPSCN 1666
Query: 1866 EDRLEQY------------EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGG 1913
E + QY +G G+C L G F C+ + P F++ C LD C
Sbjct: 1667 ELQFSQYAAMCDNVHIQKMQGDGYCLKLT-DMKGFFQPCYGLLDPLPFYESCYLDGCY-S 1724
Query: 1914 GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPC-PASCPS 1969
+ LC +LA+Y AC++ G++ +W + C V PC A CP+
Sbjct: 1725 HKKFQLCGSLAAYGEACRSFGILSTEWIEKENCS---------GVVEDPCVGADCPN 1772
Score = 832 bits (2148), Expect = 0.0
Identities = 491/1561 (31%), Positives = 727/1561 (46%), Gaps = 96/1561 (6%)
Query: 3209 GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQ-HGCQP 3267
GC + G + G FW D C+ CRC + C ASC EVC P G+ C
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCE--PKGKFFYCSA 316
Query: 3268 VSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV 3327
V T+ C +G+PHY T DG F FQG+C YLL+ C F+V NEHR AV
Sbjct: 317 VETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCL-QTSSLPFFSVEAKNEHRRGSAV 375
Query: 3328 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLD-SLLHAHLSGADVVVTTTSGL 3386
S+ + +++++ + + + +++V+ + +LP LD + + SG V T GL
Sbjct: 376 SWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGL 435
Query: 3387 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGA 3438
+ FDG + + VP +Y S CGLCGNYN++P DD G+PA W+V A
Sbjct: 436 LVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHA 495
Query: 3439 Q-GCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDA 3497
C C + C + + G D CG ++ TDGPL C +V P + C+ D
Sbjct: 496 DWKCDSGCVDNC-TQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDL 554
Query: 3498 CQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFC--PFQCPAHSHYELCGDSCPGSC 3555
C V+ + LC A+ Y CQA G + +WR C QCP+ SHY +C SCP +C
Sbjct: 555 CSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTC 614
Query: 3556 PSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSL 3615
L+A C + C EGC C+ GFVLS CVP+ +CGC D YY +G+ F+ C
Sbjct: 615 SDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQ 674
Query: 3616 CRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGT 3675
C C EGG+V C +CG E C G GC T C S + TFDG + F
Sbjct: 675 CLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSE 734
Query: 3676 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ-RQWKVTVN 3734
Y L +TC RP + + N + + R + + VA+ +++ +V +N
Sbjct: 735 FSYTLLKTCPERP---EYLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLN 791
Query: 3735 GVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 3794
G +++LP +G++ ++ + +E+ + V Y + + + + Y+ GLCG
Sbjct: 792 GQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGF 851
Query: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLPPPTCPPGSAGCIPSDKCPP 3851
YN + D+F PNG N F SW EE+ C + +
Sbjct: 852 YNANASDEFCLPNGKCTDNLAVFLESWTTFEEI-----------CNGECGDLLKACNNDS 900
Query: 3852 ELEKKYQKEEFCGLLSSPT-GPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 3910
EL K Y+ CG+++ P+ CH +V+ + C+F LC GGN S LC ++ Y
Sbjct: 901 ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARY 960
Query: 3911 VSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQC 3970
SAC+ A V PWR FCP+ECP+NSH+E C TC+ C L+ C D C+EGCQC
Sbjct: 961 ASACKNADVEVGPWRTYDFCPLECPENSHFEECI-TCTETCETLTLGPICVDSCSEGCQC 1019
Query: 3971 DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLID-NCRQQCTCH-VGKVVVCQEHSCKP 4028
D G+ G CV +CGC G +T +D +C+ C C V C+ CK
Sbjct: 1020 DEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKD 1079
Query: 4029 GQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDG 4088
+ C GG+ C + +A+C + G HY +FDG
Sbjct: 1080 DEYCMEEGGLYYCQART--------------------------DASCIVSGYGHYLTFDG 1113
Query: 4089 RKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISI 4148
FDFQ +C +L TTG S+ F VT KN++R +V+ V V G +I I
Sbjct: 1114 FPFDFQTSCPLILCTTG-SRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVI 1172
Query: 4149 HKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSS 4208
H+ V VN LP+ + G+I++ ++ DFGL+V YDW + +T+P S
Sbjct: 1173 HRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRS 1232
Query: 4209 YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPE 4268
+ GLCG + NP++D P G LA S+ +G SW D C C CP+C
Sbjct: 1233 MQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKR--DTFCQVGCGDRCPSCA- 1289
Query: 4269 DRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASY 4328
++E + L F+ CH+ V P F+K C+ D C+ GG C L +Y
Sbjct: 1290 -KVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNY 1348
Query: 4329 VAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEG 4388
+ CQ G+ + WR C +TCP NSHYE C C C A + + C CVEG
Sbjct: 1349 ASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRC---AAIRLKSDCSHYCVEG 1405
Query: 4389 CQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA 4448
C CDAG+VL+ C+ L + CGC+++G Y+E FW + C++ CRC + C P
Sbjct: 1406 CHCDAGYVLNGKSCI-LPHSCGCYSDGKYYEPKQLFW-NSDCTRRCRCF-RRNVIQCDPR 1462
Query: 4449 SCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPP 4508
C E C L +G GC T+ C A G + T DG F C ++LS C P
Sbjct: 1463 QCKSDEECA-LRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
Query: 4509 LGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDS 4568
+F + + + + ++ V I + ++ R ++V+G V +PF
Sbjct: 1522 --DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDR--NTVKVNGTQVNVPFITGL 1577
Query: 4569 LLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVG 4628
+ S +V+ T+ + + ++G + +++ + +CGLCGN+N D DD +
Sbjct: 1578 ATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLR 1637
Query: 4629 GKPA--------GWQVGGAQ------GCGECVSKPCPSPCTPEQQESFGGPDACGVISAT 4674
GKP W+ G Q C E + C + G C ++
Sbjct: 1638 GKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDM 1697
Query: 4675 DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDF 4734
G PC+GL+ P +++ C LD C LC ++A Y AC++ G EW +
Sbjct: 1698 KGFFQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKEN 1756
Query: 4735 C 4735
C
Sbjct: 1757 C 1757
Score = 793 bits (2048), Expect = 0.0
Identities = 499/1585 (31%), Positives = 733/1585 (46%), Gaps = 135/1585 (8%)
Query: 2842 NKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLA 2901
N+ C +C P E C+ +G C +TC ++G+PHYH+FDG F FQG+C Y+LA
Sbjct: 290 NEIYCQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLA 349
Query: 2902 TTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVL 2961
C + T L F+V KN++R AVS+V+ ++V G I I K G+V+VN ++
Sbjct: 350 RQ-C--LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLV 406
Query: 2962 TALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDR 3021
T+LPV++ G + + Q + DFGL V++D +++P SY + CGLCGN ++
Sbjct: 407 TSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNK 466
Query: 3022 NPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGP 3081
NP +D + P+G A S+ G SWR D C C +C C Y G +CG
Sbjct: 467 NPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGF 526
Query: 3082 LAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDW 3141
L T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DW
Sbjct: 527 LNK-TDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDW 585
Query: 3142 RAQVGCEIT--CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSAD 3199
R Q GC T CP SHY VC CP +C + LT C PC EGC+C+ GFVLS
Sbjct: 586 RTQTGCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTS 642
Query: 3200 RCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 3259
+CVPL+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC +
Sbjct: 643 QCVPLHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-E 699
Query: 3260 SGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVAN 3319
G GC P C + T DG + F Y L C P E + + N
Sbjct: 700 DGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-N 755
Query: 3320 EHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDS-LLHAHLSGADV 3378
+ + ++ R + + + + + + +++++G V LPF S L + +
Sbjct: 756 KKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNST 815
Query: 3379 VVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA------- 3431
V + +++ + + +R+ Y GLCG YN + +D+ GK
Sbjct: 816 TVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFL 875
Query: 3432 -GWQVGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPA 3487
W GEC + K C + E + + CG+I+ ++ CHG+V
Sbjct: 876 ESWTTFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVT 933
Query: 3488 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC 3547
Y++ CL CQ G+ LC +VA Y +AC+ A ++ WR DFCP +CP +SH+E C
Sbjct: 934 AYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC 993
Query: 3548 GDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFY 3607
+C +C +L+ C +C EGC CD G+ L G CV +CGC + +TF+
Sbjct: 994 -ITCTETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFW 1052
Query: 3608 PGPGCDSLCRCR-EGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFD 3666
C C C V CE C E C GG C A +C SG HY TFD
Sbjct: 1053 VDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFD 1112
Query: 3667 GHRFDFMGTCVYVLAQTCGTRPG---LHRFAVLQENVAWGNGRVSVTRVITVQVANFTLR 3723
G FDF +C +L T G+RP +F V +N + + V V +++
Sbjct: 1113 GFPFDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIV 1171
Query: 3724 LEQR-QWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
+ + + V VN + LP+ L G+I G VV+ETDFGL+V YD ++ +TVP
Sbjct: 1172 IHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPR 1231
Query: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAG 3842
+ GLCG YNG+P DD + P G A + NEFG SW V D+ C G
Sbjct: 1232 SMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW--VKRDTFC---------QVG 1280
Query: 3843 CIPSDKCPP--ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 3900
C D+CP ++E + ++ C L+ + S CH V+P K+C+FD C+ GG +
Sbjct: 1281 C--GDRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAV 1338
Query: 3901 SILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQC 3960
CS + Y S CQ G V WRN T C + CP NSHYE C C C+A+ C
Sbjct: 1339 QTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDC 1398
Query: 3961 PDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVV 4020
C EGC CD+G++ NG++C+ CGCY +G YYEP+Q +C ++C C V+
Sbjct: 1399 SHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQ 1458
Query: 4021 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 4080
C CK + C G+ C + + C GG GV
Sbjct: 1459 CDPRQCKSDEECALRNGVRGCFSTKTSY---------CLAAGG-GV-------------- 1494
Query: 4081 PHYHSFDGRKFDFQGTCNYVLAT--TGCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVV 4137
+ +FDG F C +VL+T P +S Q + F + N +P Y+
Sbjct: 1495 --FRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEE 1552
Query: 4138 TVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFG--LQVSY 4195
+ N V+VNG +P ++ +S+ LV D +Q+ Y
Sbjct: 1553 QILINDRN---------TVKVNGTQVNVPFITG---LATKIYSSEGFLVIDTSPDIQIYY 1600
Query: 4196 DWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLC 4255
+ + +++ VCGLCGN + + +D V G S + SW+ G
Sbjct: 1601 NGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGM---- 1656
Query: 4256 WDECRGSCPTCPEDRLEQY------------EGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
+ R P+C E + QY +G G+C L+ G F C+ + P F
Sbjct: 1657 --QKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTD-MKGFFQPCYGLLDPLPF 1713
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC--------------E 4349
++ C LD C + LC +LA+Y AC++ G++ +W + C
Sbjct: 1714 YESCYLDGCY-SHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPN 1772
Query: 4350 ITCPENSHYEVCGPPCPASCPSPAP 4374
TC + E+CG C P P
Sbjct: 1773 RTCELGNGRELCG------CIEPPP 1791
Score = 791 bits (2042), Expect = 0.0
Identities = 498/1581 (31%), Positives = 730/1581 (46%), Gaps = 135/1581 (8%)
Query: 1645 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 1704
C +C P E C+ +G C +TC ++G+PHYH+FDG F FQG+C Y+LA C
Sbjct: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-C 352
Query: 1705 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 1764
+ T L F+V KN++R AVS+V+ ++V G I I K G+V+VN ++T+LP
Sbjct: 353 --LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLP 410
Query: 1765 VSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 1824
V++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP +
Sbjct: 411 VTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLD 470
Query: 1825 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPG 1884
D + P+G A S+ G SWR D C C +C C Y G +CG L
Sbjct: 471 DFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNK- 529
Query: 1885 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 1944
T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR Q
Sbjct: 530 TDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQT 589
Query: 1945 GCEIT--CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 2002
GC T CP SHY VC S CP +C + LT C PC EGC+C+ GFVLS +CVP
Sbjct: 590 GCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQCVP 646
Query: 2003 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 2062
L+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC + G
Sbjct: 647 LHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-EDGYQ 703
Query: 2063 GCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2122
GC P C + T DG + F Y L C P E + + N+ +
Sbjct: 704 GCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NKKKP 759
Query: 2123 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDS-LLHAHLSGADVVVTT 2181
++ R + + + + + + +++++G V LPF S L + + V +
Sbjct: 760 DAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVES 819
Query: 2182 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQ 2233
+++ + + +R+ Y GLCG YN + +D+ GK W
Sbjct: 820 KGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWT 879
Query: 2234 VGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQYFQ 2290
GEC + K C + E + + CG+I+ ++ CHG+V Y++
Sbjct: 880 TFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYR 937
Query: 2291 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 2350
CL CQ G+ LC +VA Y +AC+ A ++ WR DFCP +CP +SH+E C +C
Sbjct: 938 TCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITC 996
Query: 2351 PGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPG 2410
+C +L+ C +C EGC CD G+ L G CV +CGC + +TF+
Sbjct: 997 TETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLD 1056
Query: 2411 CDSLCRCR-EGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRF 2469
C C C V CE C E C GG C A +C SG HY TFDG F
Sbjct: 1057 CQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPF 1116
Query: 2470 DFMGTCVYVLAQTCGTRPG---LHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR 2526
DF +C +L T G+RP +F V +N + + V V +++ + +
Sbjct: 1117 DFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRA 1175
Query: 2527 -QWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 2585
+ V VN + LP+ L G+I G VV+ETDFGL+V YD ++ +TVP +
Sbjct: 1176 YKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQN 1235
Query: 2586 LMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPS 2645
GLCG YNG+P DD + P G A + NEFG SW V D+ C GC
Sbjct: 1236 STYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSW--VKRDTFC---------QVGC--G 1282
Query: 2646 EECPP--ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILC 2703
+ CP ++E + ++ C L+ + S CH V+P K+C+FD C+ GG + C
Sbjct: 1283 DRCPSCAKVEGFSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTAC 1342
Query: 2704 SNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGC 2763
S + Y S CQ G V WRN T C + CP NSHYE C C C+A+ C C
Sbjct: 1343 SWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYC 1402
Query: 2764 AEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH 2823
EGC CD+G++ NG++C+ CGCY +G YYEP+Q +C ++C C V+ C
Sbjct: 1403 VEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPR 1462
Query: 2824 SCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYH 2883
CK + C G+ C + + C GG GV +
Sbjct: 1463 QCKSDEECALRNGVRGCFSTKTSY---------CLAAGG-GV----------------FR 1496
Query: 2884 SFDGRKFDFQGTCNYVLAT--TGCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAA 2940
+FDG F C +VL+T P +S Q + F + N +P Y+ +
Sbjct: 1497 TFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILI 1556
Query: 2941 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFG--LQVSYDWNW 2998
N V+VNG +P ++ +S+ LV D +Q+ Y+
Sbjct: 1557 NDRN---------TVKVNGTQVNVPFITG---LATKIYSSEGFLVIDTSPDIQIYYNGFN 1604
Query: 2999 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 3058
+ +++ VCGLCGN + + +D V G S + SW+ G +
Sbjct: 1605 VIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGM------QK 1658
Query: 3059 RGSCPTCPEDRLEQY------------EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGC 3106
R P+C E + QY +G G+C L G F C+ + P F++ C
Sbjct: 1659 RPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLT-DMKGFFQPCYGLLDPLPFYESC 1717
Query: 3107 VLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGC--------------EITCP 3152
LD C + LC +LA+Y AC++ G++ +W + C TC
Sbjct: 1718 YLDGCY-SHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCE 1776
Query: 3153 ENSHYEVCGPPCPASCPSPAP 3173
+ E+CG C P P
Sbjct: 1777 LGNGRELCG------CIEPPP 1791
Score = 783 bits (2023), Expect = 0.0
Identities = 469/1558 (30%), Positives = 717/1558 (46%), Gaps = 91/1558 (5%)
Query: 3592 GCLHDDRYYPLGQTFYPGPGCDSLCRCRE-GGEVSCEPSSCGPHETCRPSGGSLGCVAVG 3650
GC ++ G+ F+ C CRC + E+ C+ +SC P+E C P G C AV
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
Query: 3651 STTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 3710
++TC G+PHY TFDG F F G+C Y+LA+ C L F+V +N VS
Sbjct: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
Query: 3711 RVITVQVANFTLRLEQRQW-KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 3769
+ ++V+V + + + + + +V VN + LPV L G ++ Q G +ETDFGL V
Sbjct: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
Query: 3770 YDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 3829
+D +Y ++VPG+Y CGLCGNYN +P DDF +P+G A + + G SW D
Sbjct: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
Query: 3830 CLPPPTCPPGSAGCIPS-DKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 3888
C +GC+ + +C E Y ++CG L+ GPL C +VDP +
Sbjct: 499 C---------DSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHS 549
Query: 3889 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFC--PMECPQNSHYELCADT 3946
C++DLC N ++LC I AY CQA G + WR +T C ++CP SHY +C +
Sbjct: 550 CVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSS 609
Query: 3947 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLID- 4005
C CS L+A C C EGC+C+ GF+ + CVP+ +CGC +G YY +
Sbjct: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
Query: 4006 NCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 4065
NC QC C G V C +C G+VC E G QG
Sbjct: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVC-------------------------AVEDGYQG 704
Query: 4066 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQN 4125
C P E C L + H+FDG + F +Y L T CP + N+
Sbjct: 705 -CFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKT-CPE-----RPEYLEIDINKK 757
Query: 4126 RGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALL 4185
+ + +++R + + + I +V++NG LP G++ + + + +
Sbjct: 758 KPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTV 817
Query: 4186 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 4245
+ + V Y + + L ++Y GLCG + N +++ PNG ++ ++ S
Sbjct: 818 ESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLES 877
Query: 4246 WRAPGWDPLCWDECRGSCPTCPEDR--LEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
W ++ +C EC C D L+ Y CG ++ + F CH V ++
Sbjct: 878 WTT--FEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGP 4363
++ C+ +C GG+ LC ++A Y +AC+ A V + WR C + CPENSH+E C
Sbjct: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-I 994
Query: 4364 PCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSE 4423
C +C + LT +C C EGCQCD G+ L +CV + CGC G
Sbjct: 995 TCTETCET---LTLGPICVDSCSEGCQCDEGYALLGSQCVTRSE-CGCNFEGHQLATNET 1050
Query: 4424 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 4483
FW D C +C C + C C E C + G + CQ + A C G HY+
Sbjct: 1051 FWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYC-MEEGGLYYCQARTDASCIVSGYGHYL 1109
Query: 4484 TLDGHRFDFQGTCEYLLSAPCHGPPLGA-ENFTVTVANEHRGSQAVSYTRSVTLQIYNHS 4542
T DG FDFQ +C +L P + F VT NE R + + V + ++ +S
Sbjct: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
Query: 4543 LTLSARWPRKLQVDGVFVALPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 4601
+ + + + V+ + LP +L ++ G VVV T GL + +D +F+ + V
Sbjct: 1170 IVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITV 1229
Query: 4602 PAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ-----------GCGECVSKPC 4650
P + S GLCG YN +P DDL+ G A Q GCG+ C
Sbjct: 1230 PRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGD----RC 1285
Query: 4651 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 4710
PS E C +I + + CH V P +++ CL D+C G C
Sbjct: 1286 PSCAKVEGFSKV--QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACS 1343
Query: 4711 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACR 4770
+ Y + CQ G + WR C + CP +SHYE C C C ++ C C
Sbjct: 1344 WLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCV 1403
Query: 4771 EGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG 4830
EGC CDAG+VL+G +C+ CGC DG+YY ++F+ +C RRC C + C +
Sbjct: 1404 EGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSDCTRRCRCFRRNVIQC-DP 1461
Query: 4831 AACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKP 4890
C EEC L +GV+ C +T CLA GG + T DG +C++VL+ +C P
Sbjct: 1462 RQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLP 1521
Query: 4891 GDEDFSIVL--EKNAAGDL---QRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVG-RVR 4944
D F +++ +K +A +L + + + + + V V+G V +P G +
Sbjct: 1522 -DISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATK 1580
Query: 4945 VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSA 5004
+ + +V+ T+ +++ ++G + +SI + ++CGLCGNFNG+ +DD+V G
Sbjct: 1581 IYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKP 1640
Query: 5005 ASSVETFGAAWRAPGSSK-----GCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGP 5059
S +W+ G K C E Q +C + + C +L + +G
Sbjct: 1641 VVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGF 1700
Query: 5060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFC 5117
F C +L P ++ C D C K LC SLAAY AC++ G+ W C
Sbjct: 1701 FQPCYGLLDPLPFYESCYLDGC-YSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENC 1757
Score = 754 bits (1948), Expect = 0.0
Identities = 466/1604 (29%), Positives = 708/1604 (44%), Gaps = 109/1604 (6%)
Query: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQE-GGLVSCESSSCGPHEACQPSGGSLGCVAVG 1248
GC +G + G+ F+ C C C + + C+ +SC P+E C+P G C AV
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVE 318
Query: 1249 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1308
+STC G+PHY TFDG F F G+C Y+LA+ C L F+V +N VS
Sbjct: 319 TSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWV 378
Query: 1309 RVITVQVANFTLRLEQRQW-KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVA 1367
+ ++V+V + + + + + +V VN + LPV L G ++ Q G +ETDFGL V
Sbjct: 379 KELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVT 438
Query: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427
+D +Y ++VPG+Y CGLCGNYN +P DDF +P+G A + + G SW D
Sbjct: 439 FDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWK 498
Query: 1428 CLPPTPCPPGSEDCIPS-HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 1486
C C+ + +C E Y ++CG L+ GPL C +VDP +
Sbjct: 499 C---------DSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHS 549
Query: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFC--PMECPPNSHYELCADT 1544
C++DLC N ++LC I AY CQA G + WRT+T C ++CP SHY +C +
Sbjct: 550 CVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSS 609
Query: 1545 CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE-PEQTVLID 1603
C CS L+A C C EGC+C+ GF+ + CVP+ +CGC +G YY E
Sbjct: 610 CPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATA 669
Query: 1604 NCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 1663
NC QC C G + C +C G+VC E G QG
Sbjct: 670 NCTVQCLCEEGGDVYCFNKTCGSGEVC-------------------------AVEDGYQG 704
Query: 1664 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQN 1723
C P E C L + H+FDG + F +Y L T CP + N+
Sbjct: 705 -CFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKT-CP-----ERPEYLEIDINKK 757
Query: 1724 RGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALL 1783
+ + +++R + + + I +V++NG LP G++ + + + +
Sbjct: 758 KPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTV 817
Query: 1784 VADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 1843
+ + V Y + + L ++Y GLCG + N +++ PNG ++ ++ S
Sbjct: 818 ESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLES 877
Query: 1844 WRAPGWDPLCWDECRGSCPTCPEDR--LEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 1901
W ++ +C EC C D L+ Y CG + + F CH V ++
Sbjct: 878 WTT--FEEICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAY 935
Query: 1902 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGS 1961
++ C+ +C GG+ LC ++A Y +AC+ A V + WR C + CPENSH+E C
Sbjct: 936 YRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-I 994
Query: 1962 PCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSE 2021
C +C + LT +C C EGCQCD G+ L +CV + CGC G
Sbjct: 995 TCTETCET---LTLGPICVDSCSEGCQCDEGYALLGSQCV-TRSECGCNFEGHQLATNET 1050
Query: 2022 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 2081
FW D C +C C + C C E C + G + CQ + A C G HY+
Sbjct: 1051 FWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYC-MEEGGLYYCQARTDASCIVSGYGHYL 1109
Query: 2082 TLDGHRFNFQGTCEYLLSAPCHGPPLGA-ENFTVTVANEHRGSQAVSYTRSVTLQIYNHS 2140
T DG F+FQ +C +L P + F VT NE R + + V + ++ +S
Sbjct: 1110 TFDGFPFDFQTSCPLILCTTGSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYS 1169
Query: 2141 LTLSARWPRKLQVDGVFVTLPFQL-DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 2199
+ + + + V+ + LP +L ++ G VVV T GL + +D +F+ + V
Sbjct: 1170 IVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITV 1229
Query: 2200 PAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ-----------GCGECVSKPC 2248
P + S GLCG YN +P DDL+ G A Q GCG+ C
Sbjct: 1230 PRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGD----RC 1285
Query: 2249 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 2308
PS E C +I + + CH V P +++ CL D+C G C
Sbjct: 1286 PSCAKVEGFSKV--QQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACS 1343
Query: 2309 AVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACR 2368
+ Y + CQ G + WR C CP +SHYE C C C ++ C C
Sbjct: 1344 WLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCV 1403
Query: 2369 EGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPS 2428
EGC CDAG+VL+G +C+ CGC D +YY Q F+ C CRC + C+P
Sbjct: 1404 EGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFW-NSDCTRRCRCFRRNVIQCDPR 1462
Query: 2429 SCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPG 2488
C E C G GC + ++ C A+G + TFDG F C +VL+ C P
Sbjct: 1463 QCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPD 1522
Query: 2489 LHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQI 2548
+ F ++ W +++ + + + + R V VNG + +P +
Sbjct: 1523 I-SFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRN-TVKVNGTQVNVPFITGLATK 1580
Query: 2549 RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGS 2608
S G +VI+T +++ Y+ +++++ +CGLCGN+NGD DD+ G
Sbjct: 1581 IYSSEGF-LVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGK 1639
Query: 2609 QAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIP--SEECPPELEKKYQKEEFCGLLS 2666
++ SW+ + P P +E + C +K Q + +C L+
Sbjct: 1640 PVVSSVVLAQSWK----TNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLT 1695
Query: 2667 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNE 2726
G C+ L+DP + C D C LC ++ AY AC++ G W +
Sbjct: 1696 DMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQ-LCGSLAAYGEACRSFGILSTEWIEK 1754
Query: 2727 TFCP---------MECPQNSHYELCADTCSLG-----CSALSAP 2756
C +CP TC LG C + P
Sbjct: 1755 ENCSGVVEDPCVGADCPNR--------TCELGNGRELCGCIEPP 1790
Score = 731 bits (1887), Expect = 0.0
Identities = 432/1374 (31%), Positives = 668/1374 (48%), Gaps = 53/1374 (3%)
Query: 4047 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC 4106
C +C P E C+ +G C +TC ++G+PHYH+FDG F FQG+C Y+LA C
Sbjct: 294 CQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQ-C 352
Query: 4107 PGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALP 4166
+ T L F+V KN++R AVS+V+ ++V G I I K G+V+VN ++T+LP
Sbjct: 353 --LQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLP 410
Query: 4167 VSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNN 4226
V++ G + + Q + DFGL V++D +++P SY + CGLCGN ++NP +
Sbjct: 411 VTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLD 470
Query: 4227 DQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSG 4286
D + P+G A S+ G SWR D C C +C C Y G +CG L+
Sbjct: 471 DFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNK- 529
Query: 4287 TGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV 4346
T GP C V P +F CV D+C + +LC+A+ +Y CQA G+ I DWR Q
Sbjct: 530 TDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQT 589
Query: 4347 GCEIT--CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVP 4404
GC T CP SHY VC CP +C + LT C PC EGC+C+ GFVLS +CVP
Sbjct: 590 GCVSTVQCPSFSHYSVCTSSCPDTC---SDLTASRNCATPCTEGCECNQGFVLSTSQCVP 646
Query: 4405 LNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQH 4464
L+ CGC +G Y+ G FWA C+ C C GG + C +CG GEVC + G
Sbjct: 647 LHK-CGCDFDGHYYTMGEFFWATANCTVQCLCEEGG-DVYCFNKTCGSGEVCAV-EDGYQ 703
Query: 4465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 4524
GC P C + T DG + F Y L C P E + + N+ +
Sbjct: 704 GCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERP---EYLEIDI-NKKKP 759
Query: 4525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDS-LLHAHLSGADVVVTT 4583
++ R + + + + + + +++++G V LPF S L + + V +
Sbjct: 760 DAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNKNSTTVES 819
Query: 4584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQ 4635
+++ + + +R+ Y GLCG YN + +D+ GK W
Sbjct: 820 KGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWT 879
Query: 4636 VGGAQGCGEC--VSKPCPSPCTPEQQESFGGPDACGVIS-ATDGPLAPCHGLVPPAQYFQ 4692
GEC + K C + E + + CG+I+ ++ CHG+V Y++
Sbjct: 880 TFEEICNGECGDLLKACNNDS--ELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYR 937
Query: 4693 GCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC 4752
CL CQ G+ LC +VA Y +AC+ A ++G WR DFCPL+CP +SH+E C +C
Sbjct: 938 TCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEEC-ITC 996
Query: 4753 PVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPE 4812
+C +L+ C +C EGC CD G+ L G CV +CGC +G E F+ +
Sbjct: 997 TETCETLTLGPICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLD 1056
Query: 4813 CERRCEC-GPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRV 4871
C+ C C G V C E C E C E G+ C A C+ +G HY+T DG
Sbjct: 1057 CQIFCYCSGTDNRVHC-ETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFP 1115
Query: 4872 YDLHGSCSYVLAQVCHPKPGDEDFS--IVLEKNAAGD------LQRLLVTVAGQ--VVSL 4921
+D SC +L +P + F +V KN D ++++ VTV G V+
Sbjct: 1116 FDFQTSCPLILCTT-GSRPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHR 1174
Query: 4922 AQGQQVTVDGEAVALPVAVG--RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
A V V+ E + LP+ +G ++ + + G ++V++T GL++++D L +++P +
Sbjct: 1175 AYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQ 1234
Query: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
GLCG +NGN DD +P G ASSV FG +W + C GCG + CP C
Sbjct: 1235 NSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTF--CQVGCGDR-CPSCAKV 1291
Query: 5040 ETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTA 5099
E + + C + N F+ C + ++P+ +++ C++D C G C L Y +
Sbjct: 1292 EGFS-KVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYAS 1350
Query: 5100 ACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDD 5159
CQ G+ V WR + C + CP +SHY C CQ CAA+ + C+ C EGC CD
Sbjct: 1351 TCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDA 1410
Query: 5160 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVC 5219
++L+ CI CGC +G+Y SDC+ RC C + + C C C
Sbjct: 1411 GYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEEC 1470
Query: 5220 EVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVV 5278
++ R C++T+ C+ + G TFDGA + + LS+ C L + I + ++
Sbjct: 1471 ALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPD-ISFQLII 1529
Query: 5279 AEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSL 5338
+ + V+ + + + + V VNG +V++P + + + +G L
Sbjct: 1530 NFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKI-YSSEGFL 1588
Query: 5339 LVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAM 5392
++ +Q++ + + +S K+CG CGNF+GD T+D+ + KP +
Sbjct: 1589 VIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVV 1642
Score = 306 bits (783), Expect = 5e-82
Identities = 192/611 (31%), Positives = 289/611 (47%), Gaps = 29/611 (4%)
Query: 4793 GCLHDGRYYPLGEVFYPGPECERRCECGP-GGHVTCQEGAACGPHEECRLEDGVQACHAT 4851
GC G++ GEVF+ C +C C + CQE A+C P+E C + C A
Sbjct: 259 GCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQE-ASCSPYEVCEPKGKFFYCSAV 317
Query: 4852 GCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGD 4906
C+ G HY T DG ++ GSC+Y+LA+ C FS+ + +A
Sbjct: 318 ETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSW 377
Query: 4907 LQRLLVTVAGQVVSLAQGQ--QVTVDGEAVALPVA--VGRVRVTAEGRNMVLQTTKGLRL 4962
++ L V V G + + +G +V V+ +LPV +G V++ G + ++T GL +
Sbjct: 378 VKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLV 437
Query: 4963 LFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK 5022
FDG + +S+P + CGLCGN+N N DDF+ P+G A SV G +WR +
Sbjct: 438 TFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADW 497
Query: 5023 GCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA 5082
C GC C C A A Y ++ CG L GP C V+ P+ + CVYDLC+
Sbjct: 498 KCDSGC-VDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCS 556
Query: 5083 QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFC--PLHCPAHSHYSICTRTCQGSCAA 5140
+ + LC+++ AY CQA G+ + WRT + C + CP+ SHYS+CT +C +C+
Sbjct: 557 VRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSD 616
Query: 5141 LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSL-LTSDCSERCS 5199
L+ C T C EGCEC+ F+LS C+P+ CGC +G Y + T++C+ +C
Sbjct: 617 LTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATANCTVQCL 676
Query: 5200 CSSSSGLTCQAAGCPPGRVCEVKAEARNCWATR-GLCVLSVGANLTTFDGARGATTSPGV 5258
C + C C G VC V+ + C+ R +C+LS L TFDGA A S
Sbjct: 677 CEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFS 736
Query: 5259 YELSSRCPGLQNTIPWYRVVAEVQICHGKTEA----VGQVHIFFQDGMVTL--TPNKGVW 5312
Y L CP P Y E+ I K +A + + I D V + V
Sbjct: 737 YTLLKTCP----ERPEY---LEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVK 789
Query: 5313 VNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGAC 5372
+NG V+LP + S V K V V G + + +S + G C
Sbjct: 790 LNGQEVELPFFHPSGKLEIYRNKNSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLC 849
Query: 5373 GNFDGDQTNDW 5383
G ++ + ++++
Sbjct: 850 GFYNANASDEF 860
>gi|161019170 mucin 5AC [Homo sapiens]
Length = 6207
Score = 561 bits (1446), Expect = e-159
Identities = 559/2118 (26%), Positives = 822/2118 (38%), Gaps = 386/2118 (18%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311
C G HY TFDG F F G C YV ++ CG + +Q + + +++RV+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
Query: 1312 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 1371
++V ++L + V VNG + LP + + Q S +E GL + ++
Sbjct: 138 -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP 1431
+ + + Y + CGLCG++NG P + ++ EFGN + P C P
Sbjct: 193 DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
Query: 1432 TPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 1491
P PP +C EL G L S C LVD L+ C DL
Sbjct: 252 VPEPP--RNCSTGFGICEEL--------LHGQL------FSGCVALVDVGSYLEACRQDL 295
Query: 1492 CLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
C LS +C + Y C AGG + WR FCP +CP N Y C C+ C
Sbjct: 296 CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
Query: 1550 SALSAPPQCQDGCAEGCQCDSGFLYN--GQ-ACVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606
S C+D C GC C G + + GQ CVP+ +C C +NG Y P T D C
Sbjct: 356 SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-C- 413
Query: 1607 QQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCL 1666
CTC G+ CQE C PG
Sbjct: 414 TNCTCSGGR-WSCQEVPC-PG--------------------------------------- 432
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG- 1725
TC + G H+ +FDG+++ G C+YVL T C + FTV + + G
Sbjct: 433 -----TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAELRRCGL 480
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV- 1784
+ + ++ VT++ G + G+V +N + T LP+S A+ +++ + ++ ++
Sbjct: 481 TDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQ 538
Query: 1785 ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1842
GLQ++ ++ + L G CGLCGN + +D +G + + +
Sbjct: 539 TSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFN 598
Query: 1843 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFF 1902
+++ P + C E+ AP G P + C V
Sbjct: 599 TFKTQAACPNIRNSFEDPCSLSVEN--------------APRMGAP-SACRTLV------ 637
Query: 1903 KGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSP 1962
L A V + G V W EN+ + + G
Sbjct: 638 ----------------LALAAMLVVPQAETQGPVEPSW-----------ENAGHTMDGG- 669
Query: 1963 CPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEF 2022
P S P+ P V P LS + +PL G G +A+
Sbjct: 670 APTSSPTRRVSFVPPVTVFPS-----------LSRKQMLPLPAGKGVFAS---------- 708
Query: 2023 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 2082
P GG G+ L P+ H + ST WGD HY T
Sbjct: 709 -------------PKGGG-----PDLGVQLPPALNPA--HNGRVCST-----WGDFHYKT 743
Query: 2083 LDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 2142
DG F F G C Y+ S C E+F V + GS+ V TR V I L
Sbjct: 744 FDGDVFRFPGLCNYVFSEHCRA---AYEDFNVQLRRGLVGSRPV-VTRVV---IKAQGLV 796
Query: 2143 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 2202
L A + ++G LP+ LL SG + V+ L+ ++G+ L +
Sbjct: 797 LEAS-NGSVLINGQREELPYSRTGLL-VEQSGDYIKVSIRLVLTFLWNGEDSALLELDPK 854
Query: 2203 YAGSLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQ---GCGECVSKPCPSP---CTPE 2255
YA CGLCG++N PA ++ A + Q G Q G E P P P CT E
Sbjct: 855 YANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGNCTDE 914
Query: 2256 QQESFGGPDACGVISAT-DGP-LAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
+ G+ T GP A CH LV Y C D C+ P C Y
Sbjct: 915 E----------GICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTCP---CATFVEY 961
Query: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVC 2373
C AG Q R WR P+ CP CP + ++ CG C +C + + CE C +GC C
Sbjct: 962 SRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFC 1021
Query: 2374 DAG---FVLSGDT---CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEP 2427
G VL T C+P+GQC C H R Y G +F C S C C GG C+
Sbjct: 1022 PPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF--NTTCSS-CTC-SGGLWQCQD 1077
Query: 2428 SSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 2487
C TC G H +T+D + +D G C YVL++ C
Sbjct: 1078 LPC-------------------PGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCAD-- 1116
Query: 2488 GLHRFAVLQENVAWG-NGRVSVTRVITVQV-ANFTLRLEQRQWKVTVNGVDMKLPVVLAN 2545
F VL E G + + +T+ + T Q V +N + +LP+ AN
Sbjct: 1117 --SSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAAN 1174
Query: 2546 GQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV---PGNYYQLMCGLCGNYNGDPKDDF 2602
+ + +V++T GL++ LV ++V V P + Q MCGLCGN+N + DDF
Sbjct: 1175 ITL-FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQ-MCGLCGNFNQNQADDF 1232
Query: 2603 QKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFC 2662
+G F N+W+ C + C +E + +C
Sbjct: 1233 TALSGVVEATGAAFANTWK---------AQAACANARNSF--EDPCSLSVENENYARHWC 1281
Query: 2663 GLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEP 2722
L+ P S CH +++P+ +C+FD C + LC+ + +YV AC A G Q+
Sbjct: 1282 SRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSD 1341
Query: 2723 WRNE--TFCPMECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEGCQCDSG-FLYN 2776
WR+ T CP++ Y D C C LS A + C +GC C +G FL +
Sbjct: 1342 WRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLND 1401
Query: 2777 GQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKV------------------- 2817
ACVP Q+C CY +G P + V + C+C GK+
Sbjct: 1402 AGACVPAQECPCYAHGTVLAPGEVVHDEGA--VCSCTGGKLSCLGASLQKSTGCAAPMVY 1459
Query: 2818 -----------------------VVCQEHSCKPGQVCQP---SGGILSCVNKDPC----H 2847
V C C G VC P S G C+ ++ C +
Sbjct: 1460 LDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHN 1519
Query: 2848 GVTCRPQETCKEQGGQGVCL-PNYE-------ATCWLWGDPHYHSFDGRKFDFQGTCNYV 2899
T +P ET + C +E TC +GD H+ +FDG ++ F+G+C Y+
Sbjct: 1520 EATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYI 1579
Query: 2900 LATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS-------YVRVVTVAALGTNISIHKDEI 2952
LA C +T G F + T+N G + +V V T A+ T +
Sbjct: 1580 LAQDYCGDNTTHG--TFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPA 1637
Query: 2953 GKVRVNGVLTALPVSVADGRISVTQGASKA-------------------LLVADFGLQVS 2993
+ G LP + + + +G KA L++ G+ VS
Sbjct: 1638 PREASVGFRQRLP-PLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVS 1696
Query: 2994 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 3053
+D V + L Y G VCGLCGN D N ND + ++ +G SW+ P
Sbjct: 1697 WDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKL---SPS 1753
Query: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM- 3112
C D P C + + C L G F C + V +++ CV D C
Sbjct: 1754 CPDALAPKDP-CTANPFRKSWAQKQCSIL---HGPTFAACRSQVDSTKYYEACVNDACAC 1809
Query: 3113 -GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGPPC 3164
GGD + C A+A+Y AC AG+ + WR C + C P HY+ CG PC
Sbjct: 1810 DSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPC 1868
Query: 3165 PASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGS 3221
+C +P + + + P +EGC +C + + CGC+ +G Y++ G+
Sbjct: 1869 LKTCRNP---SGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGA 1925
Query: 3222 EFWADGTCSQWCRCGPGG 3239
C Q C C P G
Sbjct: 1926 RVPTAENC-QSCNCTPSG 1942
Score = 415 bits (1067), Expect = e-115
Identities = 362/1289 (28%), Positives = 519/1289 (40%), Gaps = 200/1289 (15%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 3332
C WGD HY T DG F F G C Y+ S C E+F V + GS+ V TR
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA---AYEDFNVQLRRGLVGSRPV-VTRV 788
Query: 3333 VTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 3392
V I L L A L ++G LP+ LL SG + V+ L+ ++G
Sbjct: 789 V---IKAQGLVLEASNGSVL-INGQREELPYSRTGLL-VEQSGDYIKVSIRLVLTFLWNG 843
Query: 3393 DSFVRLRVPAAYAGSLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQ---GCGECVSKP 3448
+ L + YA CGLCG++N PA ++ A + Q G Q G E P
Sbjct: 844 EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDP 903
Query: 3449 CPSP---CTPEQQESFGGPDACGVISATD-GP-LAPCHGLVPPAQYFQGCLLDACQVQGH 3503
P P CT E+ G+ T GP A CH LV Y C D C+
Sbjct: 904 LPLPAGNCTDEE----------GICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC 953
Query: 3504 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563
P C Y C AG Q R WR P+ CP CP + ++ CG C +C + +
Sbjct: 954 P---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQL 1010
Query: 3564 CESACREGCVCDAG---FVLSGDT---CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 3617
CE C +GC C G VL T C+P+GQC C H R Y G +F C S C
Sbjct: 1011 CEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF--NTTCSS-CT 1067
Query: 3618 CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCV 3677
C GG C+ C TC G H +T+D +D G C
Sbjct: 1068 C-SGGLWQCQDLPC-------------------PGTCSVQGGAHISTYDEKLYDLHGDCS 1107
Query: 3678 YVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQV-ANFTLRLEQRQWKVTVNG 3735
YVL++ C F VL E G + + +T+ + T Q V +N
Sbjct: 1108 YVLSKKCAD----SSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNS 1163
Query: 3736 VDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV---PGNYYQLMCGLC 3792
+ +LP+ AN + + +V++T GL++ LV ++V V P + Q MCGLC
Sbjct: 1164 IYTQLPLSAANITL-FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQ-MCGLC 1221
Query: 3793 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPE 3852
GN+N + DDF +G F N+W+ + C +A D C
Sbjct: 1222 GNFNQNQADDFTALSGVVEATGAAFANTWK---AQAAC--------ANARNSFEDPCSLS 1270
Query: 3853 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVS 3912
+E + +C L+ P S CH +++P+ +C+FD C + LC+ + +YV
Sbjct: 1271 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 1330
Query: 3913 ACQAAGGHVEPWRNE--TFCPMECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEG 3967
AC A G + WR+ T CP++ Y D C C LS A + C +G
Sbjct: 1331 ACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDG 1390
Query: 3968 CQCDSG-FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKV-------- 4018
C C +G FL + ACVP Q+C CY +G P + V + C+C GK+
Sbjct: 1391 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGA--VCSCTGGKLSCLGASLQ 1448
Query: 4019 ----------------------------------VVCQEHSCKPGQVCQP---SGGILSC 4041
V C C G VC P S G C
Sbjct: 1449 KSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGC 1508
Query: 4042 VTKDPC----HGVTCRPQETCKEQGGQGVCL-PNYE-------ATCWLWGDPHYHSFDGR 4089
+ ++ C + T +P ET + C +E TC +GD H+ +FDG
Sbjct: 1509 IAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGD 1568
Query: 4090 KFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS-------YVRVVTVAAL 4142
++ F+G+C Y+LA C +T G F + T+N G + +V V T A+
Sbjct: 1569 RYSFEGSCEYILAQDYCGDNTTHG--TFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAV 1626
Query: 4143 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKA------------------- 4183
T + + G LP + + + +G KA
Sbjct: 1627 STPDPAANEPAPREASVGFRQRLP-PLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIF 1685
Query: 4184 LLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 4243
L++ G+ VS+D V + L Y G VCGLCGN D N ND + ++ +G
Sbjct: 1686 LVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFG 1745
Query: 4244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
SW+ P C D P C + + C L G F C + V +
Sbjct: 1746 NSWKL---SPSCPDALAPKDP-CTANPFRKSWAQKQCSILH---GPTFAACRSQVDSTKY 1798
Query: 4304 FKGCVLDVCM--GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC----PENS- 4356
++ CV D C GGD + C A+A+Y AC AG+ + WR C + C P
Sbjct: 1799 YEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGC 1857
Query: 4357 --HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLSADRCVPLNNGCGCW 4412
HY+ CG PC +C +P + + + P +EGC +C + + CGC+
Sbjct: 1858 EWHYQPCGAPCLKTCRNP---SGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCY 1914
Query: 4413 -ANGTYHEAGSEFWADGTCSQWCRCGPGG 4440
+G Y++ G+ C Q C C P G
Sbjct: 1915 DKDGNYYDVGARVPTAENC-QSCNCTPSG 1942
Score = 400 bits (1029), Expect = e-110
Identities = 380/1407 (27%), Positives = 553/1407 (39%), Gaps = 278/1407 (19%)
Query: 466 AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRV 525
A + VC GD HY TFDG + G C+Y E C F+V+ + GSR V
Sbjct: 727 AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA--AYEDFNVQLRRGLVGSRPV 784
Query: 526 SYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGL 585
V V ++A + + G V L++ QR LP S + L V QSG +++ L
Sbjct: 785 --VTRVVIKAQGLVLEASNGSV---LINGQREELPYSRTG--LLVEQSGD--YIKVSIRL 835
Query: 586 VVTYDWDCQ--LALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASSWKL 642
V+T+ W+ + L L ++ +Q CGLCG++NG PA ++F + L P ++F + KL
Sbjct: 836 VLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKL 893
Query: 643 DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVY 702
D C D CT + + +C T L FA CH +D +L C
Sbjct: 894 DGPTEQCPDPLPLPAGNCT-------DEEGICHR-TLLGPAFAECHALVDSTAYLAACAQ 945
Query: 703 DLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSC 762
DLC C Y++ C G +WR P CP +CP N +++ CG C +C
Sbjct: 946 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 1002
Query: 763 NGAAAPSNCSGRPCVEGCVCLPGFVA------SGGACVPASSCGCTFQGLQLAPGQEVWA 816
+ C CV+GC C PG + C+P C CT G +PG
Sbjct: 1003 SNPQRAQLCEDH-CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF-- 1059
Query: 817 DELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFD 876
+ C CTC+G Q C+D CP GTC G H ++D
Sbjct: 1060 NTTCS-SCTCSGGLWQ--CQD-LPCP-------------------GTCSVQGGAHISTYD 1096
Query: 877 GRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVAVR 935
+ +D G C+Y+L C + +F VL E G + + +AV + G A+R
Sbjct: 1097 EKLYDLHGDCSYVLSKKCADS----SFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIR 1152
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGR-DAVVRTDFGLTVTYDW--NARVTAKVP 992
+ G V ++ + LP AA+ + +F VV+T GL + +V ++
Sbjct: 1153 VQADGGVFLNSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 1210
Query: 993 SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLD 1052
++ +CGLCGNFN + ADD G A AF N+W+ + C
Sbjct: 1211 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA--ACANARNSFEDPCS 1268
Query: 1053 SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
V + +++ C L DP F CHS ++P+ +C++D C LC AL++Y
Sbjct: 1269 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 1328
Query: 1113 AAACQAAGATVHPWRSEELCP---LSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSEC 1166
AC A G + WR + +C +CP Y C +C + V
Sbjct: 1329 VHACAAKGVQLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVP 1387
Query: 1167 HEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQTFY-------------------- 1205
+GC C G F +C+P C C GT PG+ +
Sbjct: 1388 VDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASL 1447
Query: 1206 ----------------------PGPGCDSLCHCQEGGLVSCESSSCGPHEACQP---SGG 1240
PG C CH + V C S+ C C P S G
Sbjct: 1448 QKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD---VGCFSTHCVSGCVCPPGLVSDG 1504
Query: 1241 SLGCVA--------------------VGSSTCQ------------------ASGDPHYTT 1262
S GC+A V +TC A GD H+ T
Sbjct: 1505 SGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFIT 1564
Query: 1263 FDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1321
FDG R+ F G+C Y+LAQ CG F ++ EN+ G + ++ I + V T
Sbjct: 1565 FDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAP 1624
Query: 1322 L---------EQRQWKVTVNGVDMKLP------VVLANGQIRASQHGSD----------- 1355
E + +V G +LP ++L G +A G
Sbjct: 1625 AVSTPDPAANEPAPREASV-GFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMG 1683
Query: 1356 --VVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNAN 1413
+VIET G+ V++D V + + +Y ++CGLCGN++ + +DF + S G+A
Sbjct: 1684 IFLVIET-HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDAL 1742
Query: 1414 EFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
EFGNSW+ L P+ CP + P C +K ++ C +L PT ++
Sbjct: 1743 EFGNSWK--------LSPS-CP---DALAPKDPCTANPFRKSWAQKQCSILHGPT--FAA 1788
Query: 1474 CHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPME 1531
C VD + C+ D C GG+ C+ + AY AC AG V WRT CP+
Sbjct: 1789 CRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLF 1847
Query: 1532 CP---PNS----HYELCADTCSLGCSALSAPPQC------QDGCAEGCQCDSGFLYNGQA 1578
C P+ HY+ C C C S C +GC C F +N
Sbjct: 1848 CDFYNPHGGCEWHYQPCGAPCLKTCRNPSG--HCLVDLPGLEGCYPKCPPSQPF-FNEDQ 1904
Query: 1579 CVPIQQCGCY-HNGVYYEPEQTV-LIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGI 1636
+ QCGCY +G YY+ V +NC Q C C PSG
Sbjct: 1905 MKCVAQCGCYDKDGNYYDVGARVPTAENC-QSCN-------------------CTPSG-- 1942
Query: 1637 LSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTC- 1695
+ C H + C YE + + D Y++ DG C
Sbjct: 1943 IQC-----AHSLE--------------ACTCTYEDRTYSYQDVIYNTTDGLGACLIAICG 1983
Query: 1696 ---NYVLATTGCPGVSTQGLTPFTVTT 1719
+ CPG T TPFT TT
Sbjct: 1984 SNGTIIRKAVACPG--TPATTPFTFTT 2008
Score = 349 bits (895), Expect = 5e-95
Identities = 360/1399 (25%), Positives = 514/1399 (36%), Gaps = 274/1399 (19%)
Query: 2874 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 2933
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 785
Query: 2934 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 2993
V + A G + G V +NG LP S R + S + L ++
Sbjct: 786 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 838
Query: 2994 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAPGW 3050
+ WN + L Y CGLCG+ + P ++ + N L P +G + G
Sbjct: 839 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGP 896
Query: 3051 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110
C D C ++ G C G F CHA V ++ C D+
Sbjct: 897 TEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQDL 947
Query: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 3170
C C Y C AG +WR C TCP N ++ CG PC +C +
Sbjct: 948 CRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 1004
Query: 3171 PAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSEFW 3224
P +CE CV+GC C G ++ C+PL C C G + G+ F
Sbjct: 1005 P---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTSF- 1059
Query: 3225 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTL 3284
+ TCS C C GG C C C G H T
Sbjct: 1060 -NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHISTY 1095
Query: 3285 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 3343
D +D G C Y+LS C +FTV G + + ++VTL +
Sbjct: 1096 DEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA 1150
Query: 3344 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LRVP 3401
+ + + ++ ++ LP ++ S +VV T GL L ++ +R+
Sbjct: 1151 IRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 1210
Query: 3402 AAYAGSLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 3456
A+ G +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 1211 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLS 1270
Query: 3457 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 3516
+ C ++ + + CH ++ P + C+ D C + LC A+++YV
Sbjct: 1271 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 1330
Query: 3517 ACQAAGAQLREWRRPDFCPF--QCPAHSHYELCGDSCPGSCPSLSAPEGCESAC---REG 3571
AC A G QL +WR + CP Y D+C +C LS + S +G
Sbjct: 1331 ACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDG 1390
Query: 3572 CVCDAG-FVLSGDTCVPVGQCGC------------LHDD---------RYYPLGQTFYPG 3609
C C AG F+ CVP +C C +HD+ + LG +
Sbjct: 1391 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKS 1450
Query: 3610 PGCDSL-----CRCREGG-------------EVSCEPSSCGPHETCRP---SGGSLGCVA 3648
GC + C G +V C + C C P S GS GC+A
Sbjct: 1451 TGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIA 1510
Query: 3649 --------------------VGSTTCQ------------------ASGDPHYTTFDGHRF 3670
V TC A GD H+ TFDG R+
Sbjct: 1511 EEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRY 1570
Query: 3671 DFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL----- 3724
F G+C Y+LAQ CG F ++ EN+ G + ++ I + V T
Sbjct: 1571 SFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPD 1630
Query: 3725 ----EQRQWKVTVNGVDMKLP------VVLANGQIRASQHGSD-------------VVIE 3761
E + +V G +LP ++L G +A G +VIE
Sbjct: 1631 PAANEPAPREASV-GFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689
Query: 3762 TDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW 3821
T G+ V++D V + + +Y +CGLCGN++ + +DF + S G+A EFGNSW
Sbjct: 1690 T-HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSW 1748
Query: 3822 EEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVD 3881
+ P+CP A P D C +K ++ C +L PT ++C VD
Sbjct: 1749 K---------LSPSCPDALA---PKDPCTANPFRKSWAQKQCSILHGPT--FAACRSQVD 1794
Query: 3882 PQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMEC----P 3935
+ C+ D C GG+ C+ + AY AC AG V WR CP+ C P
Sbjct: 1795 STKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNP 1853
Query: 3936 QNS---HYELCADTCSLGCSALS----APLQCPDGCAEGCQCDSGFLYNGQACVPIQQCG 3988
HY+ C C C S L +GC C F +N + QCG
Sbjct: 1854 HGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPF-FNEDQMKCVAQCG 1912
Query: 3989 CY-HNGVYYEPEQTV-LIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDP 4046
CY +G YY+ V +NC Q C C PSG + C
Sbjct: 1913 CYDKDGNYYDVGARVPTAENC-QSCN-------------------CTPSG--IQC----- 1945
Query: 4047 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTC----NYVLA 4102
H + C YE + + D Y++ DG C +
Sbjct: 1946 AHSLE--------------ACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRK 1991
Query: 4103 TTGCPGVSTQGLTPFTVTT 4121
CPG T TPFT TT
Sbjct: 1992 AVACPG--TPATTPFTFTT 2008
Score = 347 bits (890), Expect = 2e-94
Identities = 357/1399 (25%), Positives = 514/1399 (36%), Gaps = 274/1399 (19%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 785
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 1792
V + A G + G V +NG LP S R + S + L ++
Sbjct: 786 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 838
Query: 1793 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAPGW 1849
+ WN + L Y CGLCG+ + P ++ + N L P +G + G
Sbjct: 839 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGP 896
Query: 1850 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 1909
C D C ++ G C G F CHA V ++ C D+
Sbjct: 897 TEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQDL 947
Query: 1910 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPS 1969
C C Y C AG +WR C TCP N ++ CGSPC +C +
Sbjct: 948 CRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 1004
Query: 1970 PAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSEFW 2023
P +CE CV+GC C G ++ C+PL C C G + G+ F
Sbjct: 1005 P---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTSF- 1059
Query: 2024 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTL 2083
+ TCS C C GG C C C G H T
Sbjct: 1060 -NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHISTY 1095
Query: 2084 DGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 2142
D ++ G C Y+LS C +FTV G + + ++VTL +
Sbjct: 1096 DEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA 1150
Query: 2143 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LRVP 2200
+ + + ++ ++ LP ++ S +VV T GL L ++ +R+
Sbjct: 1151 IRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 1210
Query: 2201 AAYAGSLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 2255
A+ G +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 1211 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLS 1270
Query: 2256 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 2315
+ C ++ + + CH ++ P + C+ D C + LC A+++YV
Sbjct: 1271 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 1330
Query: 2316 ACQAAGAQLREWRRPDFCPF--QCPAHSHYELCGDSCPGSCPSLSAPEGCESAC---REG 2370
AC A G QL +WR + CP Y D+C +C LS + S +G
Sbjct: 1331 ACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDG 1390
Query: 2371 CVCDAG-FVLSGDTCVPVGQCGC------------LHDD---------RYYPLGQTFYPG 2408
C C AG F+ CVP +C C +HD+ + LG +
Sbjct: 1391 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKS 1450
Query: 2409 PGCDSL-----CRCREGG-------------EVSCEPSSCGPHETCRP---SGGSLGCVA 2447
GC + C G +V C + C C P S GS GC+A
Sbjct: 1451 TGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIA 1510
Query: 2448 --------------------VGSTTCQ------------------ASGDPHYTTFDGRRF 2469
V TC A GD H+ TFDG R+
Sbjct: 1511 EEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRY 1570
Query: 2470 DFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL----- 2523
F G+C Y+LAQ CG F ++ EN+ G + ++ I + V T
Sbjct: 1571 SFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPD 1630
Query: 2524 ----EQRQWKVTVNGVDMKLP------VVLANGQIRASQHGSD-------------VVIE 2560
E + +V G +LP ++L G +A G +VIE
Sbjct: 1631 PAANEPAPREASV-GFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689
Query: 2561 TDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW 2620
T G+ V++D V + + +Y +CGLCGN++ + +DF + S G+A EFGNSW
Sbjct: 1690 T-HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSW 1748
Query: 2621 EEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVD 2680
+ P+CP + P + C +K ++ C +L PT ++C VD
Sbjct: 1749 K---------LSPSCP---DALAPKDPCTANPFRKSWAQKQCSILHGPT--FAACRSQVD 1794
Query: 2681 PQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMEC----P 2734
+ C+ D C GG+ C+ + AY AC AG V WR CP+ C P
Sbjct: 1795 STKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNP 1853
Query: 2735 QNS---HYELCADTCSLGCSALS----APLQCPDGCAEGCQCDSGFLYNGQACVPIQQCG 2787
HY+ C C C S L +GC C F +N + QCG
Sbjct: 1854 HGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPF-FNEDQMKCVAQCG 1912
Query: 2788 CY-HNGAYYEPEQTV-LIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDP 2845
CY +G YY+ V +NC Q C C PSG + C +
Sbjct: 1913 CYDKDGNYYDVGARVPTAENC-QSCN-------------------CTPSG--IQCAH--- 1947
Query: 2846 CHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTC----NYVLA 2901
C YE + + D Y++ DG C +
Sbjct: 1948 ----------------SLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRK 1991
Query: 2902 TTGCPGVSTQGLTPFTVTT 2920
CPG T TPFT TT
Sbjct: 1992 AVACPG--TPATTPFTFTT 2008
Score = 345 bits (886), Expect = 5e-94
Identities = 340/1345 (25%), Positives = 486/1345 (36%), Gaps = 242/1345 (17%)
Query: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 785
Query: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 4194
V + A G + G V +NG LP S R + S + L ++
Sbjct: 786 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 838
Query: 4195 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAPGW 4251
+ WN + L Y CGLCG+ + P ++ + N L P +G + G
Sbjct: 839 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGP 896
Query: 4252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311
C D C ++ G C G F CHA V ++ C D+
Sbjct: 897 TEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQDL 947
Query: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371
C C Y C AG +WR C TCP N ++ CG PC +C +
Sbjct: 948 CRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 1004
Query: 4372 PAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSEFW 4425
P +CE CV+GC C G ++ C+PL C C G + G+ F
Sbjct: 1005 P---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTSF- 1059
Query: 4426 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTL 4485
+ TCS C C GG C C C G H T
Sbjct: 1060 -NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHISTY 1095
Query: 4486 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 4544
D +D G C Y+LS C +FTV G + + ++VTL +
Sbjct: 1096 DEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA 1150
Query: 4545 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LRVP 4602
+ + + ++ ++ LP ++ S +VV T GL L ++ +R+
Sbjct: 1151 IRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 1210
Query: 4603 AAYAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 4657
A+ +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 1211 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLS 1270
Query: 4658 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 4717
+ C ++ + + CH ++ P + C+ D C + LC A+++YV
Sbjct: 1271 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 1330
Query: 4718 ACQAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESAC---RE 4771
AC A G QL +W R C CP Y D+C +C LS + S +
Sbjct: 1331 ACAAKGVQLSDW-RDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVD 1389
Query: 4772 GCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVFY---------------------- 4808
GC C AG F+ CVP +C C G GEV +
Sbjct: 1390 GCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQK 1449
Query: 4809 --------------------PGPECERRCE----------------CGPG------GHVT 4826
PG EC R C C PG G
Sbjct: 1450 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 1509
Query: 4827 CQEGAAC-------GPHEECRLEDGVQAC--------HATGCGRCLANGGIHYITLDGRV 4871
+E C P E R++ C H G C+A G H+IT DG
Sbjct: 1510 AEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 1569
Query: 4872 YDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 4930
Y GSC Y+LAQ C F IV E G V + V+
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629
Query: 4931 GEAVALP----------------------VAVGRVRVTAEGRN------------MVLQT 4956
A P + G + A G ++
Sbjct: 1630 DPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689
Query: 4957 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 5016
T G+ + +D + + + ++GR+CGLCGNF+ N +DF + S FG +W+
Sbjct: 1690 THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWK 1749
Query: 5017 APGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQC 5076
S C + P+ C A + + C L P FA C++ + ++Y+ C
Sbjct: 1750 L---SPSCPDALAPK--DPCTANPFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEAC 1802
Query: 5077 VYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS-------HY 5127
V D CA GD C ++AAY AC AG+ V WRT CPL C ++ HY
Sbjct: 1803 VNDACACDSGGDCECFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHY 1861
Query: 5128 SICTRTCQGSC--------AALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGC-TH 5178
C C +C L GL GC +C F Q C V CGC
Sbjct: 1862 QPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKC---PPSQPFFNEDQMKC--VAQCGCYDK 1916
Query: 5179 NGRYLPVNSSLLTSDCSERCSCSSSSGLTC----QAAGCP-PGRVCEVKAEARNCWATRG 5233
+G Y V + + T++ + C+C + SG+ C +A C R + N G
Sbjct: 1917 DGNYYDVGARVPTAENCQSCNC-TPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLG 1975
Query: 5234 LCVLSV-GANLTTFDGARGATTSPG 5257
C++++ G+N T R A PG
Sbjct: 1976 ACLIAICGSNGTII---RKAVACPG 1997
Score = 332 bits (850), Expect = 8e-90
Identities = 361/1376 (26%), Positives = 505/1376 (36%), Gaps = 287/1376 (20%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713
C GD HY TFDG F F G C YV ++ C R A NV G V V+
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVV 785
Query: 3714 T-VQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL 3772
T V + L LE V +NG +LP + + Q G + + L ++
Sbjct: 786 TRVVIKAQGLVLEASNGSVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLTFLWNG 843
Query: 3773 VYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDS 3828
+ + Y CGLCG++NG P N A NA +FGN + P
Sbjct: 844 EDSALLELDPKYANQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTE 898
Query: 3829 PCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLK 3887
C P P G+ C E E C + GP + CH LVD L
Sbjct: 899 QCPDPLPLPAGN--------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLA 941
Query: 3888 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTC 3947
C DLC + C+ Y C AGG WR CP CP N ++ C C
Sbjct: 942 ACAQDLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC 998
Query: 3948 SLGCSALSAPLQCPDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGVYYEPE 3999
+ CS C D C +GC C G ++G C+P+ QC C H G Y P
Sbjct: 999 TDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPG 1056
Query: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCK 4059
+ + CTC SGG+ C PC G TC
Sbjct: 1057 TS--FNTTCSSCTC---------------------SGGLWQCQDL-PCPG-------TCS 1085
Query: 4060 EQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTV 4119
QGG H ++D + +D G C+YVL+ C S FTV
Sbjct: 1086 VQGGA-----------------HISTYDEKLYDLHGDCSYVLSKK-CADSS------FTV 1121
Query: 4120 TTKNQNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQ 4178
+ + G + ++ VT++ G + +I G V +N + T LP+S A+ I++
Sbjct: 1122 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAAN--ITLFT 1179
Query: 4179 GASKALLV-ADFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL 4235
+S ++V GLQ+ +V V L ++ G +CGLCGN ++N +D +G +
Sbjct: 1180 PSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVV 1239
Query: 4236 APSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCH 4295
+ + +W+A + C E+ E Y +C L+ F+ CH
Sbjct: 1240 EATGAAFANTWKAQAACANARNSFEDPCSLSVEN--ENY-ARHWCSRLTDPNSA-FSRCH 1295
Query: 4296 AHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI--TCP 4353
+ + P+ F C+ D C D LC AL+SYV AC A GV + DWR V + CP
Sbjct: 1296 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 1355
Query: 4354 ENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCW 4412
++ Y C +C + V+GC C AG F+ A CVP C C+
Sbjct: 1356 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQE-CPCY 1414
Query: 4413 ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS----------------------- 4449
A+GT G +G C GG L C AS
Sbjct: 1415 AHGTVLAPGEVVHDEGAV-----CSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGT 1469
Query: 4450 --------------------CGLGEVC--GLLPSGQHGCQPVSTAEC------------- 4474
C G VC GL+ G GC C
Sbjct: 1470 PGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETI 1529
Query: 4475 -----------QAWGDPHYVTL--------------DGHRFDFQGTCEYLLSAPCHGPPL 4509
+ W H + L DG R+ F+G+CEY+L+ G
Sbjct: 1530 RVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNT 1589
Query: 4510 GAENFTVTVANEHRGSQAVSYTRSVTL--------QIYNHSLTLSARWPRKLQVDGVFVA 4561
F + N G+ + ++++ L + + PR+ V
Sbjct: 1590 THGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRL 1649
Query: 4562 LPFQLDSLL--------HAHLSGAD----------VVVTTTSGLSLAFDGDSFVRLRVPA 4603
P Q L+ A G D +V T G+++++D + V +R+
Sbjct: 1650 PPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQ 1709
Query: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGEC--VSKPCP------SPCT 4655
Y +CGLCGN++ + +D VG A G +S CP PCT
Sbjct: 1710 DYKGRVCGLCGNFDDNAINDFATRSRS----VVGDALEFGNSWKLSPSCPDALAPKDPCT 1765
Query: 4656 PEQQESFGGPDACGVISATDGP-LAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAV 4712
C ++ GP A C V +Y++ C+ DAC G C AV
Sbjct: 1766 ANPFRKSWAQKQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAV 1822
Query: 4713 ATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSC--PS----- 4758
A Y AC AG + WR PD CPL C ++ HY+ CG C +C PS
Sbjct: 1823 AAYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLV 1881
Query: 4759 -LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERR 4816
L EGC C + + D V QCGC DG YY +G C+
Sbjct: 1882 DLPGLEGCYPKCP-----PSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQ-S 1935
Query: 4817 CECGPGGHVTCQEGAACGPHEECR----------LEDGVQACHATGCGRCLANGGI 4862
C C P G AC E R DG+ AC CG +NG I
Sbjct: 1936 CNCTPSGIQCAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICG---SNGTI 1988
Score = 329 bits (844), Expect = 4e-89
Identities = 358/1390 (25%), Positives = 504/1390 (36%), Gaps = 291/1390 (20%)
Query: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 2512
C GD HY TFDG F F G C YV ++ C R A NV G V V+
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVV 785
Query: 2513 T-VQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL 2571
T V + L LE V +NG +LP + + Q G + + L ++
Sbjct: 786 TRVVIKAQGLVLEASNGSVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLTFLWNG 843
Query: 2572 VYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDS 2627
+ + Y CGLCG++NG P N A NA +FGN + P
Sbjct: 844 EDSALLELDPKYANQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTE 898
Query: 2628 PCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLK 2686
C P P G+ C E E C + GP + CH LVD L
Sbjct: 899 QCPDPLPLPAGN--------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLA 941
Query: 2687 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTC 2746
C DLC + C+ Y C AGGQ WR CP CP N ++ C C
Sbjct: 942 ACAQDLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPC 998
Query: 2747 SLGCSALSAPLQCPDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGAYYEPE 2798
+ CS C D C +GC C G ++G C+P+ QC C H G Y P
Sbjct: 999 TDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPG 1056
Query: 2799 QTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCK 2858
+ + CTC SGG+ C + PC G TC
Sbjct: 1057 TS--FNTTCSSCTC---------------------SGGLWQCQDL-PCPG-------TCS 1085
Query: 2859 EQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTV 2918
QGG H ++D + +D G C+YVL+ C S FTV
Sbjct: 1086 VQGGA-----------------HISTYDEKLYDLHGDCSYVLSKK-CADSS------FTV 1121
Query: 2919 TTKNQNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQ 2977
+ + G + ++ VT++ G + +I G V +N + T LP+S A+ + T
Sbjct: 1122 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITL-FTP 1180
Query: 2978 GASKALLVADFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 3035
+ ++ GLQ+ +V V L ++ G +CGLCGN ++N +D +G +
Sbjct: 1181 SSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVE 1240
Query: 3036 PSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHA 3095
+ + +W+A + C E+ E Y +C L F+ CH+
Sbjct: 1241 ATGAAFANTWKAQAACANARNSFEDPCSLSVEN--ENY-ARHWCSRLTDPNSA-FSRCHS 1296
Query: 3096 HVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI--TCPE 3153
+ P+ F C+ D C D LC AL+SYV AC A GV + DWR V + CP+
Sbjct: 1297 IINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPK 1356
Query: 3154 NSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWA 3212
+ Y C +C + V+GC C AG F+ A CVP C C+A
Sbjct: 1357 SQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQE-CPCYA 1415
Query: 3213 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS------------------------ 3248
+GT G +G C GG L C AS
Sbjct: 1416 HGTVLAPGEVVHDEGAV-----CSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTP 1470
Query: 3249 -------------------CGLGEVC--GLLPSGQHGCQPVSTAEC-------------- 3273
C G VC GL+ G GC C
Sbjct: 1471 GAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIR 1530
Query: 3274 ----------QAWGDPHYVTL--------------DGHRFDFQGTCEYLLSAPCHGPPLG 3309
+ W H + L DG R+ F+G+CEY+L+ G
Sbjct: 1531 VDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTT 1590
Query: 3310 AENFTVTVANEHRGSQAVSYTRSVTL--------QIYNHSLTLSARWPRKLQVDGVFVTL 3361
F + N G+ + ++++ L + + PR+ V
Sbjct: 1591 HGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLP 1650
Query: 3362 PFQLDSLL--------HAHLSGAD----------VVVTTTSGLSLAFDGDSFVRLRVPAA 3403
P Q L+ A G D +V T G+++++D + V +R+
Sbjct: 1651 PLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQD 1710
Query: 3404 YAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGEC--VSKPCP------SPCTP 3455
Y G +CGLCGN++ + +D VG A G +S CP PCT
Sbjct: 1711 YKGRVCGLCGNFDDNAINDFATRSRS----VVGDALEFGNSWKLSPSCPDALAPKDPCTA 1766
Query: 3456 EQQESFGGPDACGVISATDGP-LAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVA 3512
C ++ GP A C V +Y++ C+ DAC G C AVA
Sbjct: 1767 NPFRKSWAQKQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVA 1823
Query: 3513 TYVAACQAAGAQLREWRRPDFCPFQCPAHS-------HYELCGDSCPGSC--PS------ 3557
Y AC AG + WR PD CP C ++ HY+ CG C +C PS
Sbjct: 1824 AYAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVD 1882
Query: 3558 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL-HDDRYYPLGQTFYPGPGCDSLC 3616
L EGC C + + D V QCGC D YY +G C S C
Sbjct: 1883 LPGLEGCYPKCP-----PSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQS-C 1936
Query: 3617 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTC 3676
C G + C S C + D Y T DG +G C
Sbjct: 1937 NCTPSG-IQCAHS-------------LEACTCTYEDRTYSYQDVIYNTTDG-----LGAC 1977
Query: 3677 VYVLAQTCGT 3686
+ + + GT
Sbjct: 1978 LIAICGSNGT 1987
Score = 251 bits (641), Expect = 1e-65
Identities = 250/966 (25%), Positives = 373/966 (38%), Gaps = 180/966 (18%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C GG C C QG H +T+D + YD+ G CSY + + C++ +F+V
Sbjct: 1066 CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADS----SFTV 1121
Query: 514 EAKNEHRG-SRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
A+ G + + + VT+ ++ G V +++ ++LP+S + L
Sbjct: 1122 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFT-P 1180
Query: 573 SGPRAVVELVFGLVVTYDWD--CQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 630
S VV+ GL + Q+ + L Q Q+CGLCGN+N + ADDF G +
Sbjct: 1181 SSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVE 1240
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCH 688
FA++WK + ++ C + A+H+ C LT + F+ CH
Sbjct: 1241 ATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHW-----CSRLTDPNSAFSRCH 1295
Query: 689 DTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP--ANCPLSCP 746
++P+PF C++D C LC LS+Y AC G+ + DWR +CP
Sbjct: 1296 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 1355
Query: 747 ANSRYELCGPACPTSCNG-AAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTF 803
+ RY AC +C G + A CS V+GC C G F+ GACVPA C C
Sbjct: 1356 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYA 1415
Query: 804 QGLQLAPGQEVWADELCQRRCT-----CNGATHQ-----------VTCRDKQSCPAGERC 847
G LAPG EV DE CT C GA+ Q + C + + G C
Sbjct: 1416 HGTVLAPG-EVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 1474
Query: 848 -------------------------SVQNGLLGCYPDRFGTCQGSG-----------DPH 871
V +G GC + C + D +
Sbjct: 1475 LRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCN 1534
Query: 872 YVSFDGRRFD-----FMGTCT--------------YLLVGS---------CGQNAALPAF 903
+ RR++ +GTC Y GS CG N F
Sbjct: 1535 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 1594
Query: 904 RVLVENEHRGSQTVSYTRAVRV--------------------EARGVKVAVRREYPGQVL 943
R++ EN G+ + ++A+++ R V R+ P
Sbjct: 1595 RIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQS 1654
Query: 944 VDDVLQYLPFQA------ADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAE 997
+ +LQ F+A D ++ G V+ T G+ V++D V ++ Y
Sbjct: 1655 YELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKG 1713
Query: 998 ALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQ 1057
+CGLCGNF+ + +D A R +AL FGNSW + P C P D A
Sbjct: 1714 RVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSW--KLSPSC----PDALAPKDPCTAN 1767
Query: 1058 QLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATY 1112
+ ++ +C IL P F C S++D CV D C G C A+A Y
Sbjct: 1768 PFRKSWAQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAY 1825
Query: 1113 AAACQAAGATVHPWRSEELCPLSCP---PHS----HYEACSYGCPLSCGD------LPVP 1159
A AC AG V WR+ + CPL C PH HY+ C C +C + + +P
Sbjct: 1826 AQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLP 1884
Query: 1160 GGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQ-GTYHPPGQTFYPGPGCDSLCHCQE 1218
G G C+ C + F + + +A CGC + G Y+ G C S C+C
Sbjct: 1885 GLEG--CYPKCPPSQPF-FNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQS-CNCTP 1940
Query: 1219 GGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVL 1278
G+ S C + D Y T DG +G C+ +
Sbjct: 1941 SGIQCAHSLE--------------ACTCTYEDRTYSYQDVIYNTTDG-----LGACLIAI 1981
Query: 1279 AQTCGT 1284
+ GT
Sbjct: 1982 CGSNGT 1987
Score = 213 bits (542), Expect = 4e-54
Identities = 168/585 (28%), Positives = 253/585 (43%), Gaps = 61/585 (10%)
Query: 461 KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 520
+A A + VC G HY TFDG + G C+Y E C F+++ +
Sbjct: 70 RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
Query: 521 GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 580
+ + V ++ + LT+G V LV+ LP S+ + + QS VE
Sbjct: 128 SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
Query: 581 LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 639
GLV+ ++ D L L L ++ ++ CGLCG++NG P + L+ + L P +EF +
Sbjct: 181 ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
Query: 640 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699
K+DD C+D C+ G E L G L F+ C +D +LE
Sbjct: 239 QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
Query: 700 CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 757
C DLC L +C L+ Y++ C G DWR P CP CP N +Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 758 CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 814
C +C+ C CV GC C G V CVP S C C + G APG
Sbjct: 351 CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 815 WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 874
D C CTC+G + +C++ CP GTC G H+ +
Sbjct: 410 STD--C-TNCTCSGG--RWSCQE-VPCP-------------------GTCSVLGGAHFST 444
Query: 875 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 933
FDG+++ G C+Y+L C + AF VL E G + + + ++V + G +
Sbjct: 445 FDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDGAQTV 500
Query: 934 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 990
V + G+V ++ + LP AA+ V +FR ++ +T GL + ++ +
Sbjct: 501 VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
Query: 991 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE 1035
+ CGLCGNFN ADD G A A AF N+++ +
Sbjct: 559 LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQ 603
Score = 202 bits (514), Expect = 7e-51
Identities = 170/597 (28%), Positives = 241/597 (40%), Gaps = 79/597 (13%)
Query: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 4528
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 4529 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 4588
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 4589 LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 4647
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 4648 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 4705
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 4706 -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 4764
+C +A Y C AG +WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 4765 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 4821
CE C GC C G VL G T CVPV +C C+++G Y G + +C C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDC-TNCTCS- 419
Query: 4822 GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 4881
GG +CQE C G C GG H+ T DG+ Y +HG CSYV
Sbjct: 420 GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 4882 LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTV------AGQVVSLAQGQQVTVDGEA 4933
L + C F+++ E G D + L +V A VV + +V ++
Sbjct: 460 LTKPC----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIY 515
Query: 4934 VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 4990
LP++ V + ++ QT+ GL+L L M + RG+ CGLCGNFN
Sbjct: 516 TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Query: 4991 GNWSDDFVLPNG----SAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAP 5043
+DDF +G +AA+ TF P + C L+ E AP
Sbjct: 576 SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENAP 625
Score = 187 bits (475), Expect = 2e-46
Identities = 157/567 (27%), Positives = 235/567 (41%), Gaps = 63/567 (11%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 3327
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 3328 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLS 3387
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 3388 LAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 3446
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 3447 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 3504
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 3505 -GGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563
+C +A Y C AG ++WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 3564 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCRE 3620
CE C GC C G VL G T CVPV +C C+++ Y G T+ C + C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC-S 419
Query: 3621 GGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVL 3680
GG SC+ C TC G H++TFDG ++ G C YVL
Sbjct: 420 GGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVL 460
Query: 3681 AQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANF-TLRLEQRQWKVTVNGVDM 3738
+ C + F VL E G + + +T+ + T+ + + +V +N +
Sbjct: 461 TKPCDS----SAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYT 516
Query: 3739 KLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVR--VTVPGNYYQLMCGLCGNY 3795
+LP+ AN I R S ++ +T GL++ LV ++ + + CGLCGN+
Sbjct: 517 QLPISAANVTIFRPSTF--FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNF 574
Query: 3796 NGDPKDDFQKPNGSQAGNANEFGNSWE 3822
N DDF+ +G A F N+++
Sbjct: 575 NSIQADDFRTLSGVVEATAAAFFNTFK 601
Score = 184 bits (467), Expect = 2e-45
Identities = 153/557 (27%), Positives = 247/557 (44%), Gaps = 61/557 (10%)
Query: 4845 VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 4900
V+A + GR C G HY T DG V+ G C+YV ++ C EDF+I L +
Sbjct: 69 VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
Query: 4901 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 4960
++AA L R+L+ V G V+ L +G V V+G V LP + V + ++ GL
Sbjct: 127 ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
Query: 4961 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGS 5020
L+++ D LL+ + + + + CGLCG+FNG +L + + + +E FG +
Sbjct: 186 VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
Query: 5021 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 5078
++ C + P+ C C +L + Q F+ C A++ Y C
Sbjct: 245 TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
Query: 5079 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 5136
DLC + + +C +LA Y+ C AG + WR FCP CP + Y C C
Sbjct: 294 DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
Query: 5137 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 5192
+C+ C C GC C + +L Q C+PV C C +NG Y P + ++
Sbjct: 354 TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
Query: 5193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 5252
DC+ C+CS +CQ CP G C + GA+ +TFDG +
Sbjct: 412 DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
Query: 5253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 5310
Y L+ C + V+AE++ C +E + DG T+ K
Sbjct: 452 VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKAS 506
Query: 5311 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 5366
V++N + LP A+V++ R ++ + G+Q + L ++ + ++ G
Sbjct: 507 GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
Query: 5367 KLCGACGNFDGDQTNDW 5383
+ CG CGNF+ Q +D+
Sbjct: 566 QTCGLCGNFNSIQADDF 582
Score = 176 bits (447), Expect = 4e-43
Identities = 153/568 (26%), Positives = 236/568 (41%), Gaps = 58/568 (10%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRV-LVENEHRGSQTVSYTRA 922
C G HY +FDG F F G C Y+ CG AA F + L ++ + T+S
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCG--AAYEDFNIQLRRSQESAAPTLS---R 135
Query: 923 VRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 982
V ++ GV + + + G VLV+ LPF + +Q + V GL + ++
Sbjct: 136 VLMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSGVLIQ--QSSSYTKVEARLGLVLMWN 190
Query: 983 WNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGA 1042
+ + ++ + YA CGLCG+FNG P L + FGN Q+ P
Sbjct: 191 HDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNL-QKMDDPTEQC 248
Query: 1043 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1102
+P P + + + G L F C + +D + C D C
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTD 302
Query: 1103 --GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1160
+C LA Y+ C AG WR + CP CP + Y C C +C +
Sbjct: 303 LLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSR 362
Query: 1161 GCGSECHEGCVCDEGFALSG---ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQ 1217
C C GC C EG L C+P++ C CV+ G + PG T+ C + C C
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC- 418
Query: 1218 EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYV 1277
GG SC+ C TC G H++TFDG+++ G C YV
Sbjct: 419 SGGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 1278 LAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANF-TLRLEQRQWKVTVNGVD 1335
L + C + F VL E G + + +T+ + T+ + + +V +N +
Sbjct: 460 LTKPCDS----SAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIY 515
Query: 1336 MKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVR--VTVPGNYYQQMCGLCGN 1392
+LP+ AN I R S ++ +T GL++ LV ++ + + Q CGLCGN
Sbjct: 516 TQLPISAANVTIFRPSTF--FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGN 573
Query: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWE 1420
+N DDF+ +G A F N+++
Sbjct: 574 FNSIQADDFRTLSGVVEATAAAFFNTFK 601
Score = 176 bits (445), Expect = 7e-43
Identities = 173/647 (26%), Positives = 259/647 (40%), Gaps = 80/647 (12%)
Query: 2874 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 2933
C WG HY +FDG F F G CNYV + C G + + ++Q P +S V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH-C-GAAYEDFN--IQLRRSQESAAPTLSRV 136
Query: 2934 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 2993
+ G I + K G V VNG LP S + + + Q +S + A GL +
Sbjct: 137 ---LMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLVLM 188
Query: 2994 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 3053
++ + + + L + Y CGLCG+ + P ++ + T P+ G+ + DP
Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-DPT 245
Query: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113
++C+ P P + G G C L G F+ C A V S+ + C D+C
Sbjct: 246 --EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLCFC 298
Query: 3114 GGDRDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 3170
D D+L C LA Y C AG + +DWR C CP N Y C PC +C +
Sbjct: 299 E-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSN 357
Query: 3171 PAPLTTPAVCEGPCVEGCQCDAGFVL---SADRCVPLNNGCGCWANGTYHEAGSEFWADG 3227
CE CV GC C G VL CVP++ C C NG + G+ + D
Sbjct: 358 Q---EHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYSTD- 412
Query: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV-STAECQAWGDPHYVTLDG 3286
CT +C G+ CQ V C G H+ T DG
Sbjct: 413 ----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTFDG 447
Query: 3287 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLS 3345
++ G C Y+L+ PC + FTV G + + + +SVTL + +
Sbjct: 448 KQYTVHGDCSYVLTKPC-----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVV 502
Query: 3346 ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA-- 3403
+ ++ ++ ++ LP ++ S ++ T+ GL L ++L + A
Sbjct: 503 IKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPK 562
Query: 3404 YAGSLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPC--TPE 3456
G CGLCGN+N ADD + + G A + Q + PC + E
Sbjct: 563 LRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622
Query: 3457 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 3503
G P AC + LA LV P QG + + + GH
Sbjct: 623 NAPRMGAPSACRTL-----VLALAAMLVVPQAETQGPVEPSWENAGH 664
Score = 174 bits (440), Expect = 3e-42
Identities = 158/582 (27%), Positives = 238/582 (40%), Gaps = 101/582 (17%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713
C G HY TFDG F F G C YV ++ CG + +Q + + +++RV+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
Query: 3714 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 3773
++V ++L + V VNG + LP + + Q S +E GL + ++
Sbjct: 138 -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
Query: 3774 YYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCL-- 3831
+ + + Y CGLCG++NG P + ++ EFGN + P C
Sbjct: 193 DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
Query: 3832 ---PPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 3888
PP C G C +E G L S C LVD L+
Sbjct: 252 VPEPPRNCSTGFGIC---------------EELLHGQL------FSGCVALVDVGSYLEA 290
Query: 3889 CIFDLCLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADT 3946
C DLC LS +C + Y C AGG + WR FCP +CP N Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 3947 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYN--GQ-ACVPIQQCGCYHNGVYYEPEQTVL 4003
C+ CS C D C GC C G + + GQ CVP+ +C C +NG Y P T
Sbjct: 351 CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYS 410
Query: 4004 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGG 4063
D C CTC SGG SC + PC G
Sbjct: 411 TD-C-TNCTC---------------------SGGRWSC-QEVPCPG-------------- 432
Query: 4064 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 4123
TC + G H+ +FDG+++ G C+YVL T C + FTV +
Sbjct: 433 ----------TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAEL 475
Query: 4124 QNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASK 4182
+ G + + ++ VT++ G + G+V +N + T LP+S A+ +++ + ++
Sbjct: 476 RRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTF 533
Query: 4183 ALLV-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMD 4221
++ GLQ++ ++ + L G CGLCGN +
Sbjct: 534 FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Score = 173 bits (439), Expect = 4e-42
Identities = 172/647 (26%), Positives = 258/647 (39%), Gaps = 80/647 (12%)
Query: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134
C WG HY +FDG F F G CNYV + C G + + ++Q P +S V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH-C-GAAYEDFN--IQLRRSQESAAPTLSRV 136
Query: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 4194
+ G I + K G V VNG LP S + + + Q +S + A GL +
Sbjct: 137 ---LMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLVLM 188
Query: 4195 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 4254
++ + + + L + Y CGLCG+ + P ++ + T P+ G+ + DP
Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-DPT 245
Query: 4255 CWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMG 4314
++C+ P P + G G C L G F+ C A V S+ + C D+C
Sbjct: 246 --EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLCFC 298
Query: 4315 GGDRDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371
D D+L C LA Y C AG + +DWR C CP N Y C PC +C +
Sbjct: 299 E-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSN 357
Query: 4372 PAPLTTPAVCEGPCVEGCQCDAGFVL---SADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
CE CV GC C G VL CVP++ C C NG + G+ + D
Sbjct: 358 Q---EHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYSTD- 412
Query: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPV-STAECQAWGDPHYVTLDG 4487
CT +C G+ CQ V C G H+ T DG
Sbjct: 413 ----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTFDG 447
Query: 4488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLS 4546
++ G C Y+L+ PC + FTV G + + + +SVTL + +
Sbjct: 448 KQYTVHGDCSYVLTKPC-----DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVV 502
Query: 4547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA-- 4604
+ ++ ++ ++ LP ++ S ++ T+ GL L ++L + A
Sbjct: 503 IKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPK 562
Query: 4605 YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPC--TPE 4657
CGLCGN+N ADD + + G A + Q + PC + E
Sbjct: 563 LRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622
Query: 4658 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 4704
G P AC + LA LV P QG + + + GH
Sbjct: 623 NAPRMGAPSACRTL-----VLALAAMLVVPQAETQGPVEPSWENAGH 664
Score = 170 bits (430), Expect = 4e-41
Identities = 143/549 (26%), Positives = 237/549 (43%), Gaps = 70/549 (12%)
Query: 4856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD---LQRLLV 4912
C G HY T DG V+ G C+YV ++ C + EDF++ L + G + R+++
Sbjct: 733 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHC--RAAYEDFNVQLRRGLVGSRPVVTRVVI 790
Query: 4913 TVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM 4972
G V+ + G V ++G+ LP + + V G + + L L++G+ L+
Sbjct: 791 KAQGLVLEASNGS-VLINGQREELPYSRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALL 849
Query: 4973 SIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQG 5032
+ + + CGLCG+FNG + + + + + ++ FG + G ++ C + P
Sbjct: 850 ELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ-FGNLQKLDGPTEQCPDPL-PLP 907
Query: 5033 CPVCLAEETAPYESNEACGQLRNPQGP-FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 5091
C EE + R GP FA C A++ + Y C DLC C
Sbjct: 908 AGNCTDEEGICH---------RTLLGPAFAECHALVDSTAYLAACAQDLCRCP---TCPC 955
Query: 5092 RSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRC 5151
+ Y+ C AG + WR CP CP + + C C +C+ C C
Sbjct: 956 ATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHC 1015
Query: 5152 FEGCEC---------DDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSS 5202
+GC C DD ++ C+P+ C CTH GR +S T+ CS SC+
Sbjct: 1016 VDGCFCPPGRSCTVLDD---ITHSGCLPLGQCPCTHGGRTYSPGTSFNTT-CS---SCTC 1068
Query: 5203 SSGL-TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYEL 5261
S GL CQ CP G C + GA+++T+D Y L
Sbjct: 1069 SGGLWQCQDLPCP------------------GTCSVQGGAHISTYDEKLYDLHGDCSYVL 1110
Query: 5262 SSRCPGLQNTIPWYRVVAEVQICHGKTE---AVGQVHIFFQDG--MVTLTPNKGVWVNGL 5316
S +C T V+AE++ C G T+ + V + G + + + GV++N +
Sbjct: 1111 SKKCADSSFT-----VLAELRKC-GLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSI 1164
Query: 5317 RVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSND--HAGKLCGACGN 5374
LP A++++ ++V+ G+Q+ + + V V D H G++CG CGN
Sbjct: 1165 YTQLPLSA-ANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGN 1223
Query: 5375 FDGDQTNDW 5383
F+ +Q +D+
Sbjct: 1224 FNQNQADDF 1232
Score = 126 bits (316), Expect = 7e-28
Identities = 189/791 (23%), Positives = 265/791 (33%), Gaps = 164/791 (20%)
Query: 2838 LSCVNK-------DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKF 2890
++CVNK DP + C+ GG+G+ P C +WG HY +FDG +
Sbjct: 5369 VTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGIT-PG-AGICSMWGGSHYSTFDGTSY 5426
Query: 2891 DFQGTCNYVLATTGCPGVSTQGL------TPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 2944
F+G C YVL L + T P + ++ + T
Sbjct: 5427 TFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTV 5486
Query: 2945 ISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV-DVT 3003
+H E G + + + + S +SV + + + G+ V++ N +V
Sbjct: 5487 TMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTF--NGQVFQAR 5544
Query: 3004 LPSS-YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGS 3061
LP S +H G CG N +D + +GT A S +W P CW G+
Sbjct: 5545 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPT-GT 5603
Query: 3062 CPTC-PEDRLEQYEGPGFCGPLAPGT---GGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 3117
PT P + P C P F CH VPP FF C+ D C G
Sbjct: 5604 PPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRGR--L 5661
Query: 3118 DILCKALASYVAACQAAGVVIEDWRAQVG--CEITCPENSHYEVCGPPCPASCPSPAPLT 3175
++ C++L +Y C+A GV DWR G C++TCP Y+ CGP PA+C S
Sbjct: 5662 EVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RN 5717
Query: 3176 TPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 3235
EG EGC C +L C C + + E W Q C C
Sbjct: 5718 QSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSN--CQSCVC 5774
Query: 3236 GPGGGSLVCTPASCGL----------GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLD 3285
G S+ C P C G V P ++ C P + C
Sbjct: 5775 DEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNT---------- 5824
Query: 3286 GHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLS 3345
TC L C P G E ++ + G ++ L YN +
Sbjct: 5825 -------TTCPQSLPV-C---PPGQE----SICTQEEGDCCPTFRCRPQLCSYNGTFY-- 5867
Query: 3346 ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 3405
GV T P L + LSG T ++ D+
Sbjct: 5868 ----------GVGATFPGALPCHMCTCLSG------DTQDPTVQCQEDA----------- 5900
Query: 3406 GSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSP------------- 3452
C N + K V G Q CGECV C +P
Sbjct: 5901 ------CNNTTCPQGFEYKRVAG----------QCCGECVQTACLTPDGQPVQLNETWVN 5944
Query: 3453 -----CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ------ 3501
CT E+ GG A+ ++ C G + C D+CQV+
Sbjct: 5945 SHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEEDSCQVRINTTIL 6004
Query: 3502 GHPG-----------GLCPAVATYVAACQAAGAQ---LREWR-RPDFCPFQCP------- 3539
H G G CP + Y A QA Q +E R + P CP
Sbjct: 6005 WHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAILH 6064
Query: 3540 --AHSHYELCG 3548
H+ LCG
Sbjct: 6065 TYTHAVQVLCG 6075
Score = 124 bits (311), Expect = 3e-27
Identities = 135/534 (25%), Positives = 196/534 (36%), Gaps = 101/534 (18%)
Query: 1185 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
P+A+ CV++ H P + P CD C+ C+ GG
Sbjct: 5365 PVANVTCVNK---HLPIKVSDPSQPCDFHYECE-----------------CECVGGR--G 5402
Query: 1245 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 1304
+ G+ C G HY+TFDG + F G C YVL + R G N++
Sbjct: 5403 ITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFG---------NLSLYLDN 5453
Query: 1305 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF-- 1362
T T A R + +D+ L V + +G+ + + + F
Sbjct: 5454 HYCTASATAAAAAARC---PRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSK 5510
Query: 1363 -GLRVAYDLVYYVRVTVP---------GNYYQQMC----------GLCGNYNGDPKDDFQ 1402
G+ V+ +RV +P G +Q G CG + +DD
Sbjct: 5511 NGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCL 5570
Query: 1403 KPNGSQAGNANEFGNSWEEVVPDSP---CLPPTPCPPGSEDCIPSHK------CPPELEK 1453
+ +G+ A + + +W +VPDS C PT PP + P CPP+
Sbjct: 5571 QRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--- 5625
Query: 1454 KYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQ 1513
C L+ S + CH LV P CI D C G L + C ++ AY C+
Sbjct: 5626 -----PLCDLMLSQV--FAECHNLVPPGPFFNACISDHCRG--RLEVPCQSLEAYAELCR 5676
Query: 1514 AAGGHVEPWRTET--FCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQC-DS 1570
A G WR T C + CPP Y+ C C++ + PQ +G AEGC C +
Sbjct: 5677 ARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQL-EGMAEGCFCPED 5734
Query: 1571 GFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
L+N + +Q C C + + + NC Q C C G V CKP C
Sbjct: 5735 QILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSV----QCKP-LPC 5788
Query: 1631 QPSGGILSC-------VTK----DPCHGVTCRPQETCKEQGGQGVCLPNYEATC 1673
G C VT+ +PC T T VC P E+ C
Sbjct: 5789 DAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESIC 5842
Score = 122 bits (306), Expect = 1e-26
Identities = 122/468 (26%), Positives = 175/468 (37%), Gaps = 46/468 (9%)
Query: 4039 LSCVTK-------DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKF 4091
++CV K DP + C+ GG+G+ P C +WG HY +FDG +
Sbjct: 5369 VTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGIT-PG-AGICSMWGGSHYSTFDGTSY 5426
Query: 4092 DFQGTCNYVLATTGCPGVSTQGL------TPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 4145
F+G C YVL L + T P + ++ + T
Sbjct: 5427 TFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTV 5486
Query: 4146 ISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRV-DVT 4204
+H E G + + + + S +SV + + + G+ V++ N +V
Sbjct: 5487 TMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTF--NGQVFQAR 5544
Query: 4205 LPSS-YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGS 4262
LP S +H G CG N +D + +GT A S +W P CW G+
Sbjct: 5545 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPT-GT 5603
Query: 4263 CPTC-PEDRLEQYEGPGFCGP---LSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 4318
PT P + P C P F CH VPP FF C+ D C G
Sbjct: 5604 PPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRGR--L 5661
Query: 4319 DILCKALASYVAACQAAGVVIEDWRAQVG--CEITCPENSHYEVCGPPCPASCPSPAPLT 4376
++ C++L +Y C+A GV DWR G C++TCP Y+ CGP PA+C S
Sbjct: 5662 EVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RN 5717
Query: 4377 TPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 4436
EG EGC C +L C C + + E W Q C C
Sbjct: 5718 QSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSN--CQSCVC 5774
Query: 4437 GPGGGSLVCTPASCGL----------GEVCGLLPSGQHGCQPVSTAEC 4474
G S+ C P C G V P ++ C P + C
Sbjct: 5775 DEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVC 5822
Score = 122 bits (305), Expect = 1e-26
Identities = 123/438 (28%), Positives = 175/438 (39%), Gaps = 70/438 (15%)
Query: 436 VLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCS 495
V P +P +C C+ VGG+ + +C G HY+TFDG Y G C+
Sbjct: 5380 VSDPSQPCDFHYEC----ECECVGGRG--ITPGAGICSMWGGSHYSTFDGTSYTFRGNCT 5433
Query: 496 YTM----------VELCSEDDTLPAFSVEAKNEHRGSRRVS--YVGLVTVRAYSHSVSLT 543
Y + + L ++ A + A R R +S Y + V +V++
Sbjct: 5434 YVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVL----TVTMV 5489
Query: 544 RG-EVGFVLVDNQRSRLPVS--LSEGRLRVYQSGPRAV-VEL-VFGLVVTYDWDCQLALS 598
G E G +L D ++PVS S+ + V G + V++ G+ VT++ A
Sbjct: 5490 HGKEEGLILFD----QIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARL 5545
Query: 599 LPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGC----- 653
+ F + G CG + DD L DG A + A +W + D +DGC
Sbjct: 5546 PYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSR---KDGCWAPTG 5602
Query: 654 ----------QNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYD 703
++ P TP Q LC ++ L FA CH+ + P PF C+ D
Sbjct: 5603 TPPTASPAAPVSSTPTPTPCPPQ-----PLCDLM--LSQVFAECHNLVPPGPFFNACISD 5655
Query: 704 LCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN--CPLSCPANSRYELCGPACPTS 761
C G C+ L AYA+ C G+ DWR C L+CP Y+ CGP P +
Sbjct: 5656 HC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPAT 5712
Query: 762 CNGAAAPSNCSGRPCVEGCVCLPG---FVASGGACVPASSCGCTFQGLQLAPGQEVWADE 818
CN G EGC C F A G CV A C G PG E W
Sbjct: 5713 CNSRNQSPQLEG--MAEGCFCPEDQILFNAHMGICVQACPC-VGPDGFPKFPG-ERWVSN 5768
Query: 819 LCQRRCTCNGATHQVTCR 836
CQ C C+ + V C+
Sbjct: 5769 -CQ-SCVCDEGSVSVQCK 5784
Score = 120 bits (302), Expect = 3e-26
Identities = 187/791 (23%), Positives = 263/791 (33%), Gaps = 164/791 (20%)
Query: 1637 LSCVTK-------DPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKF 1689
++CV K DP + C+ GG+G+ P C +WG HY +FDG +
Sbjct: 5369 VTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGIT-PG-AGICSMWGGSHYSTFDGTSY 5426
Query: 1690 DFQGTCNYVLATTGCPGVSTQGL------TPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 1743
F+G C YVL L + T P + ++ + T
Sbjct: 5427 TFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTV 5486
Query: 1744 ISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV-DVT 1802
+H E G + + + + S +SV + + + G+ V++ N +V
Sbjct: 5487 TMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTF--NGQVFQAR 5544
Query: 1803 LPSS-YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP-GWDPLCWDECRGS 1860
LP S +H G CG N +D + +GT A S +W P CW G+
Sbjct: 5545 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPT-GT 5603
Query: 1861 CPTC-PEDRLEQYEGPGFCGPLAPGT---GGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 1916
PT P + P C P F CH VPP FF C+ D C G
Sbjct: 5604 PPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCR--GRL 5661
Query: 1917 DILCKALASYVAACQAAGVVIEDWRAQVG--CEITCPENSHYEVCGSPCPASCPSPAPLT 1974
++ C++L +Y C+A G V DWR G C++TCP Y+ CG PA+C S
Sbjct: 5662 EVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS---RN 5717
Query: 1975 TPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 2034
EG EGC C +L C C + + E W Q C C
Sbjct: 5718 QSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSN--CQSCVC 5774
Query: 2035 GPGGGSLVCTPASCGL----------GEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLD 2084
G S+ C P C G V P ++ C P + C
Sbjct: 5775 DEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNT---------- 5824
Query: 2085 GHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLS 2144
TC L C P G E ++ + G ++ L YN +
Sbjct: 5825 -------TTCPQSLPV-C---PPGQE----SICTQEEGDCCPTFRCRPQLCSYNGTFY-- 5867
Query: 2145 ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 2204
GV T P L + LSG T ++ D+
Sbjct: 5868 ----------GVGATFPGALPCHMCTCLSG------DTQDPTVQCQEDA----------- 5900
Query: 2205 GSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSP------------- 2251
C N + K V G Q CGECV C +P
Sbjct: 5901 ------CNNTTCPQGFEYKRVAG----------QCCGECVQTACLTPDGQPVQLNETWVN 5944
Query: 2252 -----CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ------ 2300
CT E+ GG A+ ++ C G + C D+CQV+
Sbjct: 5945 SHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEEDSCQVRINTTIL 6004
Query: 2301 GHPG-----------GLCPAVATYVAACQAAGAQ---LREWR-RPDFCPFQCP------- 2338
H G G CP + Y A QA Q +E R + P CP
Sbjct: 6005 WHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPLHCPNGSAILH 6064
Query: 2339 --AHSHYELCG 2347
H+ LCG
Sbjct: 6065 TYTHAVQVLCG 6075
Score = 119 bits (297), Expect = 1e-25
Identities = 142/596 (23%), Positives = 208/596 (34%), Gaps = 106/596 (17%)
Query: 2337 CPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 2391
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 5295 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5344
Query: 2392 -------CLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS-CGPHETCRPSGGSL 2443
C+ D+R L P P + C + +PS C H C
Sbjct: 5345 ENCTVARCVGDNRVVLLD----PKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGG 5400
Query: 2444 GCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGN 2503
+ G+ C G HY+TFDG + F G C YVL + R G N++
Sbjct: 5401 RGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFG---------NLSLYL 5451
Query: 2504 GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF 2563
T T A R + +D+ L V + +G+ + + + F
Sbjct: 5452 DNHYCTASATAAAAAARC---PRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGF 5508
Query: 2564 ---GLRVAYDLVYYVRVTVP---------GNYYQLMC----------GLCGNYNGDPKDD 2601
G+ V+ +RV +P G +Q G CG + +DD
Sbjct: 5509 SKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDD 5568
Query: 2602 FQKPNGSQAGNANEFGNSWEEVVPDS---PCLPPPTCPPGSEGCIPSEE------CPPEL 2652
+ +G+ A + + +W +VPDS C P PP + P CPP
Sbjct: 5569 CLQRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPP-- 5624
Query: 2653 EKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSA 2712
+ C L+ S + CH LV P CI D C G L + C ++ AY
Sbjct: 5625 ------QPLCDLMLSQV--FAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAEL 5674
Query: 2713 CQAAGGQVEPWRNET--FCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQC- 2769
C+A G WR T C + CP Y+ C C++ + Q +G AEGC C
Sbjct: 5675 CRAR-GVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQL-EGMAEGCFCP 5732
Query: 2770 DSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 2829
+ L+N + +Q C C + + + NC Q C C G V V CKP
Sbjct: 5733 EDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSV----QCKP-L 5786
Query: 2830 VCQPSGGILSCVN-----------KDPCHGVTCRPQETCKEQGGQGVCLPNYEATC 2874
C G C ++PC T T VC P E+ C
Sbjct: 5787 PCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESIC 5842
Score = 118 bits (295), Expect = 2e-25
Identities = 144/596 (24%), Positives = 211/596 (35%), Gaps = 106/596 (17%)
Query: 3538 CPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 3592
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 5295 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5344
Query: 3593 -------CLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS-CGPHETCRPSGGSL 3644
C+ D+R L P P + C + +PS C H C
Sbjct: 5345 ENCTVARCVGDNRVVLLD----PKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGG 5400
Query: 3645 GCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGN 3704
+ G+ C G HY+TFDG + F G C YVL + R G N++
Sbjct: 5401 RGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFG---------NLSLYL 5451
Query: 3705 GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF 3764
T T A R + +D+ L V + +G+ + + + F
Sbjct: 5452 DNHYCTASATAAAAAARC---PRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGF 5508
Query: 3765 ---GLRVAYDLVYYVRVTVP---------GNYYQLMC----------GLCGNYNGDPKDD 3802
G+ V+ +RV +P G +Q G CG + +DD
Sbjct: 5509 SKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDD 5568
Query: 3803 FQKPNGSQAGNANEFGNSWEEVVPDS---PCLPPPTCPPGSAGCIPSDK------CPPEL 3853
+ +G+ A + + +W +VPDS C P PP ++ P CPP
Sbjct: 5569 CLQRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPP-- 5624
Query: 3854 EKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSA 3913
+ C L+ S + CH LV P CI D C G L + C ++ AY
Sbjct: 5625 ------QPLCDLMLSQV--FAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAEL 5674
Query: 3914 CQAAGGHVEPWRNET--FCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQC- 3970
C+A G WR T C + CP Y+ C C++ + Q +G AEGC C
Sbjct: 5675 CRAR-GVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQL-EGMAEGCFCP 5732
Query: 3971 DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 4030
+ L+N + +Q C C + + + NC Q C C G V V CKP
Sbjct: 5733 EDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSV----QCKP-L 5786
Query: 4031 VCQPSGGILSC-------VTK----DPCHGVTCRPQETCKEQGGQGVCLPNYEATC 4075
C G C VT+ +PC T T VC P E+ C
Sbjct: 5787 PCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESIC 5842
Score = 114 bits (286), Expect = 2e-24
Identities = 137/557 (24%), Positives = 186/557 (33%), Gaps = 89/557 (15%)
Query: 4739 CPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 4793
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 5295 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5344
Query: 4794 -------CLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQ 4846
C+ D R L P P C C H EC E
Sbjct: 5345 ENCTVARCVGDNRVVLLD----PKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGG 5400
Query: 4847 ACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPG------DEDFSIVLE 4900
G G C GG HY T DG Y G+C+YVL + H + G D +
Sbjct: 5401 RGITPGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASA 5460
Query: 4901 KNAAG---------------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRV 4945
AA D+ + V G+ L Q+ V V V +
Sbjct: 5461 TAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGT 5520
Query: 4946 TAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAA 5005
T ++ G+ + F+G S F G CG N DD + +G+ A
Sbjct: 5521 TTMRVDI---PALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTA 5577
Query: 5006 SSVETFGAAWRAPGSSK-GCGEGCG-----PQGCPVCLAEETAPYESNEACGQLRNPQGP 5059
+S + W P S K GC G PV P C + +
Sbjct: 5578 ASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--V 5635
Query: 5060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR--TDSFC 5117
FA C ++ P +F C+ D C +G C+SL AY C+A GV WR T C
Sbjct: 5636 FAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGVC-SDWRGATGGLC 5692
Query: 5118 PLHCPAHSHYSICTRTCQGSCAA------LSGLTGCTTRCFEGCEC-DDRFLLSQGVCIP 5170
L CP Y C +C + L G+ EGC C +D+ L + + I
Sbjct: 5693 DLTCPPTKVYKPCGPIQPATCNSRNQSPQLEGMA-------EGCFCPEDQILFNAHMGIC 5745
Query: 5171 VQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS------GLTCQAAGCP-----PGRVC 5219
VQ C C + S+C + C C S L C A G P PG V
Sbjct: 5746 VQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVT 5804
Query: 5220 EVKAEARNCWATRGLCV 5236
+ A N +CV
Sbjct: 5805 VTRPRAENPCCPETVCV 5821
Score = 102 bits (253), Expect = 1e-20
Identities = 136/578 (23%), Positives = 205/578 (35%), Gaps = 123/578 (21%)
Query: 1920 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGSPCPASCP--SPAPLTT 1975
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 5267 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5322
Query: 1976 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 2035
P+ G D +PL +E W C+ RC
Sbjct: 5323 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5353
Query: 2036 PGGGSLVCTPAS---------------------CGLGEVCGLLPSGQHGCQPVSTAECQA 2074
++ P C C G G P C
Sbjct: 5354 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITP-GAGICSM 5412
Query: 2075 WGDPHYVTLDGHRFNFQGTCEYLLSAPCHGP----PLGAENFTVTVANEHRGSQAVSYTR 2130
WG HY T DG + F+G C Y+L H L +N T A+ + A R
Sbjct: 5413 WGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCT-ASATAAAAAARCPR 5471
Query: 2131 SVTLQIYNHSLTLS-----ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTS-G 2184
++++ + + L+ + + D + V+ F + +L + L + V + G
Sbjct: 5472 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALG 5531
Query: 2185 LSLAFDGDSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVG 2235
+S+ F+G F + R+P + + + G CG + DD G A W V
Sbjct: 5532 VSVTFNGQVF-QARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVP 5590
Query: 2236 GAQ--GC-------------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCH 2280
++ GC S P P+PC P+ C ++ + A CH
Sbjct: 5591 DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECH 5640
Query: 2281 GLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWR--RPDFCPFQCP 2338
LVPP +F C+ D C +G C ++ Y C+A G +WR C CP
Sbjct: 5641 NLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCP 5697
Query: 2339 AHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDDR 2397
Y+ CG P +C S + E EGC C +L + + V C C+ D
Sbjct: 5698 PTKVYKPCGPIQPATCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVGPD- 5755
Query: 2398 YYPLGQTFYPG----PGCDSLCRCREGG-EVSCEPSSC 2430
G +PG C S C C EG V C+P C
Sbjct: 5756 ----GFPKFPGERWVSNCQS-CVCDEGSVSVQCKPLPC 5788
Score = 100 bits (250), Expect = 3e-20
Identities = 136/578 (23%), Positives = 205/578 (35%), Gaps = 123/578 (21%)
Query: 3121 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGPPCPASCP--SPAPLTT 3176
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 5267 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5322
Query: 3177 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 3236
P+ G D +PL +E W C+ RC
Sbjct: 5323 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5353
Query: 3237 PGGGSLVCTPAS---------------------CGLGEVCGLLPSGQHGCQPVSTAECQA 3275
++ P C C G G P C
Sbjct: 5354 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITP-GAGICSM 5412
Query: 3276 WGDPHYVTLDGHRFDFQGTCEYLLSAPCHGP----PLGAENFTVTVANEHRGSQAVSYTR 3331
WG HY T DG + F+G C Y+L H L +N T A+ + A R
Sbjct: 5413 WGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCT-ASATAAAAAARCPR 5471
Query: 3332 SVTLQIYNHSLTLS-----ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTS-G 3385
++++ + + L+ + + D + V+ F + +L + L + V + G
Sbjct: 5472 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALG 5531
Query: 3386 LSLAFDGDSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVG 3436
+S+ F+G F + R+P + + + G CG + DD G A W V
Sbjct: 5532 VSVTFNGQVF-QARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVP 5590
Query: 3437 GAQ--GC-------------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCH 3481
++ GC S P P+PC P+ C ++ + A CH
Sbjct: 5591 DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECH 5640
Query: 3482 GLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWR--RPDFCPFQCP 3539
LVPP +F C+ D C +G C ++ Y C+A G +WR C CP
Sbjct: 5641 NLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCP 5697
Query: 3540 AHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDDR 3598
Y+ CG P +C S + E EGC C +L + + V C C+ D
Sbjct: 5698 PTKVYKPCGPIQPATCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVGPD- 5755
Query: 3599 YYPLGQTFYPG----PGCDSLCRCREGG-EVSCEPSSC 3631
G +PG C S C C EG V C+P C
Sbjct: 5756 ----GFPKFPGERWVSNCQS-CVCDEGSVSVQCKPLPC 5788
Score = 97.8 bits (242), Expect = 3e-19
Identities = 127/503 (25%), Positives = 182/503 (36%), Gaps = 75/503 (14%)
Query: 780 CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQ-RRCTCNGAT-------- 830
C P V+S P+ + GC + L E W E C RC +
Sbjct: 5308 CPTSPPPVSSAPLSSPSPAPGCD-NAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPV 5366
Query: 831 HQVTCRDK----------QSCPAGERCSVQN-GLLGCYPDRFGTCQGSGDPHYVSFDGRR 879
VTC +K Q C C + G G P G C G HY +FDG
Sbjct: 5367 ANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITPGA-GICSMWGGSHYSTFDGTS 5425
Query: 880 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEH------RGSQTVSYTRAVRVEARGVKVA 933
+ F G CTY+L+ +A + ++N + + RA+ + + + +
Sbjct: 5426 YTFRGNCTYVLMREI--HARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIV 5483
Query: 934 -----VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD---WNA 985
V + G +L D + F V V V G++VT++ + A
Sbjct: 5484 LTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQA 5543
Query: 986 RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGCGAT 1043
R+ + + E CG C N + DD R G AA+ +W + + GC A
Sbjct: 5544 RLPYSLFHNNTEGQCGTCTN---NQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWA- 5599
Query: 1044 EPGDCPKLDSLVAQQLQSKNECGILADP------KGPFRECHSKLDPQGAVRDCVYDRCL 1097
P P S A + P F ECH+ + P C+ D C
Sbjct: 5600 -PTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC- 5657
Query: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSC-- 1153
G+ C +L YA C+A G WR LC L+CPP Y+ C P +C
Sbjct: 5658 -RGRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS 5715
Query: 1154 -GDLPVPGGCGSECHEGCVCDEGFAL-SGESCLPLASCGCVHQGTYHPPGQTFYPG---- 1207
P G EGC C E L + + + +C CV P G +PG
Sbjct: 5716 RNQSPQLEGMA----EGCFCPEDQILFNAHMGICVQACPCV-----GPDGFPKFPGERWV 5766
Query: 1208 PGCDSLCHCQEGGL-VSCESSSC 1229
C S C C EG + V C+ C
Sbjct: 5767 SNCQS-CVCDEGSVSVQCKPLPC 5788
Score = 94.7 bits (234), Expect = 2e-18
Identities = 131/572 (22%), Positives = 201/572 (35%), Gaps = 122/572 (21%)
Query: 4322 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGPPCPASCP--SPAPLTT 4377
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 5267 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5322
Query: 4378 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 4437
P+ G D +PL +E W C+ RC
Sbjct: 5323 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5353
Query: 4438 PGGGSLVCTPAS---------------------CGLGEVCGLLPSGQHGCQPVSTAECQA 4476
++ P C C G G P C
Sbjct: 5354 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECECVGGRGITP-GAGICSM 5412
Query: 4477 WGDPHYVTLDGHRFDFQGTCEYLLSAPCHGP----PLGAENFTVTVANEHRGSQAVSYTR 4532
WG HY T DG + F+G C Y+L H L +N T A+ + A R
Sbjct: 5413 WGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCT-ASATAAAAAARCPR 5471
Query: 4533 SVTLQIYNHSLTLS-----ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTS-G 4586
++++ + + L+ + + D + V+ F + +L + L + V + G
Sbjct: 5472 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALG 5531
Query: 4587 LSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVG 4637
+S+ F+G F + R+P + + + G CG + DD G A W V
Sbjct: 5532 VSVTFNGQVF-QARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVP 5590
Query: 4638 GAQ--GC-------------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCH 4682
++ GC S P P+PC P+ C ++ + A CH
Sbjct: 5591 DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECH 5640
Query: 4683 GLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR--RPDFCPLQCP 4740
LVPP +F C+ D C +G C ++ Y C+A G +WR C L CP
Sbjct: 5641 NLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCP 5697
Query: 4741 AHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDGR 4799
Y+ CG P +C S + E EGC C +L + + V C C+
Sbjct: 5698 PTKVYKPCGPIQPATCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVG--- 5753
Query: 4800 YYPLGEVFYPGPECERRCECGPGGHVTCQEGA 4831
P G +PG C+ C EG+
Sbjct: 5754 --PDGFPKFPGERWVSNCQ-----SCVCDEGS 5778
Score = 56.2 bits (134), Expect = 8e-07
Identities = 70/281 (24%), Positives = 98/281 (34%), Gaps = 55/281 (19%)
Query: 5134 CQGSCAALSGLTGC-TTRCFEGCECDDRFLLS-QGVCIPVQDCGCTHN-GRYLPVNSSLL 5190
C SC L GC +T C GC C + G CI +DC C HN Y P +
Sbjct: 1474 CLRSCHTLD--VGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKP--GETI 1529
Query: 5191 TSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGAR 5250
DC+ C+C + C C G CV + TFDG R
Sbjct: 1530 RVDCN-TCTCRNRR-WECSHRLC------------------LGTCVAYGDGHFITFDGDR 1569
Query: 5251 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGK-TEAVGQVHIFFQDGMVTLTPNK 5309
+ Y L+ G T +R+V E C T + +F +
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629
Query: 5310 GVWVN---------GLRVDLP--------AEKLASVSVSRTPDGS----------LLVRQ 5342
N G R LP ++ +V+R P G LV +
Sbjct: 1630 DPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689
Query: 5343 KAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
G+ V V + + D+ G++CG CGNFD + ND+
Sbjct: 1690 THGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDF 1730
Score = 35.8 bits (81), Expect = 1.2
Identities = 50/202 (24%), Positives = 66/202 (32%), Gaps = 54/202 (26%)
Query: 4602 PAAYAASLCGLCGNYNQDPA----DDLKAVGGKPAGWQVGGAQG--CGECVSKPCPSP-- 4653
P A +C QDP +D P G++ G CGECV C +P
Sbjct: 5874 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDG 5933
Query: 4654 ----------------CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 4697
CT E+ GG A+ ++ C G + C D
Sbjct: 5934 QPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEED 5993
Query: 4698 ACQVQ------GHPG-----------GLCPAVATYVAACQAAGAQLG--EWRR--PDFCP 4736
+CQV+ H G G CP + Y A QA Q + RR + P
Sbjct: 5994 SCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVP 6053
Query: 4737 LQCP---------AHSHYELCG 4749
L CP H+ LCG
Sbjct: 6054 LHCPNGSAILHTYTHAVQVLCG 6075
>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
Length = 5765
Score = 414 bits (1064), Expect = e-114
Identities = 376/1379 (27%), Positives = 549/1379 (39%), Gaps = 256/1379 (18%)
Query: 466 AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRV 525
A + VC GD HY TFDG + G C+Y E C F+V+ + GSR V
Sbjct: 71 AHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA--AYEDFNVQLRRGLVGSRPV 128
Query: 526 SYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGL 585
V V ++A + + G V L++ QR LP S + L V QSG +++ L
Sbjct: 129 --VTRVVIKAQGLVLEASNGSV---LINGQREELPYSRTG--LLVEQSGD--YIKVSIRL 179
Query: 586 VVTYDWDCQ--LALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASSWKL 642
V+T+ W+ + L L ++ +Q CGLCG++NG PA ++F + L P ++F + KL
Sbjct: 180 VLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTP--LQFGNLQKL 237
Query: 643 DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVY 702
D C D CT + + +C T L FA CH +D +L C
Sbjct: 238 DGPTEQCPDPLPLPAGNCT-------DEEGICHR-TLLGPAFAECHALVDSTAYLAACAQ 289
Query: 703 DLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSC 762
DLC C Y++ C G +WR P CP +CP N +++ CG C +C
Sbjct: 290 DLCRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTC 346
Query: 763 NGAAAPSNCSGRPCVEGCVCLPGFVA------SGGACVPASSCGCTFQGLQLAPGQEVWA 816
+ C CV+GC C PG + C+P C CT G +PG
Sbjct: 347 SNPQRAQLCEDH-CVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF-- 403
Query: 817 DELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFD 876
+ C CTC+G Q C+D CP GTC G H ++D
Sbjct: 404 NTTCS-SCTCSGGLWQ--CQD-LPCP-------------------GTCSVQGGAHISTYD 440
Query: 877 GRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVAVR 935
+ +D G C+Y+L C + +F VL E G + + +AV + G A+R
Sbjct: 441 EKLYDLHGDCSYVLSKKCADS----SFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIR 496
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGR-DAVVRTDFGLTVTYDW--NARVTAKVP 992
+ G V ++ + LP AA+ + +F VV+T GL + +V ++
Sbjct: 497 VQADGGVFLNSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 554
Query: 993 SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLD 1052
++ +CGLCGNFN + ADD G A AF N+W+ + C
Sbjct: 555 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQA--ACANARNSFEDPCS 612
Query: 1053 SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
V + +++ C L DP F CHS ++P+ +C++D C LC AL++Y
Sbjct: 613 LSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSY 672
Query: 1113 AAACQAAGATVHPWRSEELCP---LSCPPHSHYEACSYGCPLSC---GDLPVPGGCGSEC 1166
AC A G + WR + +C +CP Y C +C + V
Sbjct: 673 VHACAAKGVQLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVP 731
Query: 1167 HEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQTFY-------------------- 1205
+GC C G F +C+P C C GT PG+ +
Sbjct: 732 VDGCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASL 791
Query: 1206 ----------------------PGPGCDSLCHCQEGGLVSCESSSCGPHEACQP---SGG 1240
PG C CH + V C S+ C C P S G
Sbjct: 792 QKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD---VGCFSTHCVSGCVCPPGLVSDG 848
Query: 1241 SLGCVA--------------------VGSSTCQ------------------ASGDPHYTT 1262
S GC+A V +TC A GD H+ T
Sbjct: 849 SGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFIT 908
Query: 1263 FDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1321
FDG R+ F G+C Y+LAQ CG F ++ EN+ G + ++ I + V ++ L
Sbjct: 909 FDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELI 968
Query: 1322 LEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGN 1381
L++ +K G P + G +VIET G+ V++D V + + +
Sbjct: 969 LQEGTFKAVARGPGGDPP-------YKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQD 1020
Query: 1382 YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Y ++CGLCGN++ + +DF + S G+A EFGNSW+ L P+ CP +
Sbjct: 1021 YKGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWK--------LSPS-CP---DAL 1068
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLS 1499
P C +K ++ C +L PT ++C VD + C+ D C GG+
Sbjct: 1069 APKDPCTANPFRKSWAQKQCSILHGPT--FAACRSQVDSTKYYEACVNDACACDSGGDCE 1126
Query: 1500 ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP---PNS----HYELCADTCSLGCSAL 1552
C+ + AY AC AG V WRT CP+ C P+ HY+ C C C
Sbjct: 1127 CFCTAVAAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNP 1185
Query: 1553 SAPPQC------QDGCAEGCQCDSGFLYNGQACVPIQQCGCY-HNGVYYEPEQTV-LIDN 1604
S C +GC C F +N + QCGCY +G YY+ V +N
Sbjct: 1186 SG--HCLVDLPGLEGCYPKCPPSQPF-FNEDQMKCVAQCGCYDKDGNYYDVGARVPTAEN 1242
Query: 1605 CRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGV 1664
C Q C C PSG + C H +
Sbjct: 1243 C-QSCN-------------------CTPSG--IQC-----AHSLE--------------A 1261
Query: 1665 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTC----NYVLATTGCPGVSTQGLTPFTVTT 1719
C YE + + D Y++ DG C + CPG T TPFT TT
Sbjct: 1262 CTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPG--TPATTPFTFTT 1318
Score = 413 bits (1061), Expect = e-114
Identities = 354/1263 (28%), Positives = 507/1263 (40%), Gaps = 182/1263 (14%)
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131
C WGD HY T DG F F G C Y+ S C E+F V + GS+ V TR
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA---AYEDFNVQLRRGLVGSRPV-VTRV 132
Query: 2132 VTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
V I L L A L ++G LP+ LL SG + V+ L+ ++G
Sbjct: 133 V---IKAQGLVLEASNGSVL-INGQREELPYSRTGLL-VEQSGDYIKVSIRLVLTFLWNG 187
Query: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQ---GCGECVSKP 2247
+ L + YA CGLCG++N PA ++ A + Q G Q G E P
Sbjct: 188 EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDP 247
Query: 2248 CPSP---CTPEQQESFGGPDACGVISATD-GP-LAPCHGLVPPAQYFQGCLLDACQVQGH 2302
P P CT E+ G+ T GP A CH LV Y C D C+
Sbjct: 248 LPLPAGNCTDEE----------GICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC 297
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
P C Y C AG Q R WR P+ CP CP + ++ CG C +C + +
Sbjct: 298 P---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQL 354
Query: 2363 CESACREGCVCDAG---FVLSGDT---CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 2416
CE C +GC C G VL T C+P+GQC C H R Y G +F C S C
Sbjct: 355 CEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF--NTTCSS-CT 411
Query: 2417 CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCV 2476
C GG C+ C TC G H +T+D + +D G C
Sbjct: 412 C-SGGLWQCQDLPC-------------------PGTCSVQGGAHISTYDEKLYDLHGDCS 451
Query: 2477 YVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQV-ANFTLRLEQRQWKVTVNG 2534
YVL++ C F VL E G + + +T+ + T Q V +N
Sbjct: 452 YVLSKKCAD----SSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNS 507
Query: 2535 VDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV---PGNYYQLMCGLC 2591
+ +LP+ AN + + +V++T GL++ LV ++V V P + Q MCGLC
Sbjct: 508 IYTQLPLSAANITL-FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQ-MCGLC 565
Query: 2592 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPE 2651
GN+N + DDF +G F N+W+ C + C
Sbjct: 566 GNFNQNQADDFTALSGVVEATGAAFANTWK---------AQAACANARNSF--EDPCSLS 614
Query: 2652 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVS 2711
+E + +C L+ P S CH +++P+ +C+FD C + LC+ + +YV
Sbjct: 615 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 674
Query: 2712 ACQAAGGQVEPWRNE--TFCPMECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEG 2766
AC A G Q+ WR+ T CP++ Y D C C LS A + C +G
Sbjct: 675 ACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDG 734
Query: 2767 CQCDSG-FLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKV-------- 2817
C C +G FL + ACVP Q+C CY +G P + V + C+C GK+
Sbjct: 735 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGA--VCSCTGGKLSCLGASLQ 792
Query: 2818 ----------------------------------VVCQEHSCKPGQVCQP---SGGILSC 2840
V C C G VC P S G C
Sbjct: 793 KSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGC 852
Query: 2841 VNKDPC----HGVTCRPQETCKEQGGQGVCL-PNYE-------ATCWLWGDPHYHSFDGR 2888
+ ++ C + T +P ET + C +E TC +GD H+ +FDG
Sbjct: 853 IAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGD 912
Query: 2889 KFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH 2948
++ F+G+C Y+LA C +T G F + T+N G T I +
Sbjct: 913 RYSFEGSCEYILAQDYCGDNTTHG--TFRIVTENIPCG---------TTGTTCSKAIKLF 961
Query: 2949 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 3008
+ + G A+ + L++ G+ VS+D V + L Y
Sbjct: 962 VESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDY 1021
Query: 3009 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 3068
G VCGLCGN D N ND + ++ +G SW+ P C D P C +
Sbjct: 1022 KGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKL---SPSCPDALAPKDP-CTAN 1077
Query: 3069 RLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCKALAS 3126
+ C L G F C + V +++ CV D C GGD + C A+A+
Sbjct: 1078 PFRKSWAQKQCSIL---HGPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAA 1134
Query: 3127 YVAACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGPPCPASCPSPAPLTTPAV 3179
Y AC AG+ + WR C + C P HY+ CG PC +C +P + +
Sbjct: 1135 YAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNP---SGHCL 1190
Query: 3180 CEGPCVEGC--QCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 3236
+ P +EGC +C + + CGC+ +G Y++ G+ C Q C C
Sbjct: 1191 VDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENC-QSCNCT 1249
Query: 3237 PGG 3239
P G
Sbjct: 1250 PSG 1252
Score = 412 bits (1060), Expect = e-114
Identities = 355/1263 (28%), Positives = 508/1263 (40%), Gaps = 182/1263 (14%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 3332
C WGD HY T DG F F G C Y+ S C E+F V + GS+ V TR
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA---AYEDFNVQLRRGLVGSRPV-VTRV 132
Query: 3333 VTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 3392
V I L L A L ++G LP+ LL SG + V+ L+ ++G
Sbjct: 133 V---IKAQGLVLEASNGSVL-INGQREELPYSRTGLL-VEQSGDYIKVSIRLVLTFLWNG 187
Query: 3393 DSFVRLRVPAAYAGSLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQ---GCGECVSKP 3448
+ L + YA CGLCG++N PA ++ A + Q G Q G E P
Sbjct: 188 EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDP 247
Query: 3449 CPSP---CTPEQQESFGGPDACGVISATD-GP-LAPCHGLVPPAQYFQGCLLDACQVQGH 3503
P P CT E+ G+ T GP A CH LV Y C D C+
Sbjct: 248 LPLPAGNCTDEE----------GICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC 297
Query: 3504 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563
P C Y C AG Q R WR P+ CP CP + ++ CG C +C + +
Sbjct: 298 P---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQL 354
Query: 3564 CESACREGCVCDAG---FVLSGDT---CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 3617
CE C +GC C G VL T C+P+GQC C H R Y G +F C S C
Sbjct: 355 CEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF--NTTCSS-CT 411
Query: 3618 CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCV 3677
C GG C+ C TC G H +T+D +D G C
Sbjct: 412 C-SGGLWQCQDLPC-------------------PGTCSVQGGAHISTYDEKLYDLHGDCS 451
Query: 3678 YVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQV-ANFTLRLEQRQWKVTVNG 3735
YVL++ C F VL E G + + +T+ + T Q V +N
Sbjct: 452 YVLSKKCAD----SSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNS 507
Query: 3736 VDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV---PGNYYQLMCGLC 3792
+ +LP+ AN + + +V++T GL++ LV ++V V P + Q MCGLC
Sbjct: 508 IYTQLPLSAANITL-FTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQ-MCGLC 565
Query: 3793 GNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPE 3852
GN+N + DDF +G F N+W+ + C +A D C
Sbjct: 566 GNFNQNQADDFTALSGVVEATGAAFANTWK---AQAAC--------ANARNSFEDPCSLS 614
Query: 3853 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVS 3912
+E + +C L+ P S CH +++P+ +C+FD C + LC+ + +YV
Sbjct: 615 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 674
Query: 3913 ACQAAGGHVEPWRNE--TFCPMECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEG 3967
AC A G + WR+ T CP++ Y D C C LS A + C +G
Sbjct: 675 ACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDG 734
Query: 3968 CQCDSG-FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKV-------- 4018
C C +G FL + ACVP Q+C CY +G P + V + C+C GK+
Sbjct: 735 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGA--VCSCTGGKLSCLGASLQ 792
Query: 4019 ----------------------------------VVCQEHSCKPGQVCQP---SGGILSC 4041
V C C G VC P S G C
Sbjct: 793 KSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGC 852
Query: 4042 VTKDPC----HGVTCRPQETCKEQGGQGVCL-PNYE-------ATCWLWGDPHYHSFDGR 4089
+ ++ C + T +P ET + C +E TC +GD H+ +FDG
Sbjct: 853 IAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGD 912
Query: 4090 KFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH 4149
++ F+G+C Y+LA C +T G F + T+N G T I +
Sbjct: 913 RYSFEGSCEYILAQDYCGDNTTHG--TFRIVTENIPCG---------TTGTTCSKAIKLF 961
Query: 4150 KDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 4209
+ + G A+ + L++ G+ VS+D V + L Y
Sbjct: 962 VESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDY 1021
Query: 4210 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 4269
G VCGLCGN D N ND + ++ +G SW+ P C D P C +
Sbjct: 1022 KGRVCGLCGNFDDNAINDFATRSRSVVGDALEFGNSWKL---SPSCPDALAPKDP-CTAN 1077
Query: 4270 RLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCKALAS 4327
+ C L G F C + V +++ CV D C GGD + C A+A+
Sbjct: 1078 PFRKSWAQKQCSILH---GPTFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAA 1134
Query: 4328 YVAACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGPPCPASCPSPAPLTTPAV 4380
Y AC AG+ + WR C + C P HY+ CG PC +C +P + +
Sbjct: 1135 YAQACHDAGLCV-SWRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNP---SGHCL 1190
Query: 4381 CEGPCVEGC--QCDAGFVLSADRCVPLNNGCGCW-ANGTYHEAGSEFWADGTCSQWCRCG 4437
+ P +EGC +C + + CGC+ +G Y++ G+ C Q C C
Sbjct: 1191 VDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENC-QSCNCT 1249
Query: 4438 PGG 4440
P G
Sbjct: 1250 PSG 1252
Score = 362 bits (930), Expect = 4e-99
Identities = 356/1371 (25%), Positives = 510/1371 (37%), Gaps = 252/1371 (18%)
Query: 2874 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 2933
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 129
Query: 2934 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 2993
V + A G + G V +NG LP S R + S + L ++
Sbjct: 130 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 182
Query: 2994 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAPGW 3050
+ WN + L Y CGLCG+ + P ++ + N L P +G + G
Sbjct: 183 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGP 240
Query: 3051 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110
C D C ++ G C G F CHA V ++ C D+
Sbjct: 241 TEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQDL 291
Query: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 3170
C C Y C AG +WR C TCP N ++ CG PC +C +
Sbjct: 292 CRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 348
Query: 3171 PAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSEFW 3224
P +CE CV+GC C G ++ C+PL C C G + G+ F
Sbjct: 349 P---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTSF- 403
Query: 3225 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTL 3284
+ TCS C C GG C C C G H T
Sbjct: 404 -NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHISTY 439
Query: 3285 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 3343
D +D G C Y+LS C +FTV G + + ++VTL +
Sbjct: 440 DEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA 494
Query: 3344 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LRVP 3401
+ + + ++ ++ LP ++ S +VV T GL L ++ +R+
Sbjct: 495 IRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 554
Query: 3402 AAYAGSLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 3456
A+ G +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 555 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLS 614
Query: 3457 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 3516
+ C ++ + + CH ++ P + C+ D C + LC A+++YV
Sbjct: 615 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 674
Query: 3517 ACQAAGAQLREWRRPDFCPF--QCPAHSHYELCGDSCPGSCPSLSAPEGCESAC---REG 3571
AC A G QL +WR + CP Y D+C +C LS + S +G
Sbjct: 675 ACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDG 734
Query: 3572 CVCDAG-FVLSGDTCVPVGQCGC------------LHDD---------RYYPLGQTFYPG 3609
C C AG F+ CVP +C C +HD+ + LG +
Sbjct: 735 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKS 794
Query: 3610 PGCDSL-----CRCREGG-------------EVSCEPSSCGPHETCRP---SGGSLGCVA 3648
GC + C G +V C + C C P S GS GC+A
Sbjct: 795 TGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIA 854
Query: 3649 --------------------VGSTTCQ------------------ASGDPHYTTFDGHRF 3670
V TC A GD H+ TFDG R+
Sbjct: 855 EEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRY 914
Query: 3671 DFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQW 3729
F G+C Y+LAQ CG F ++ EN+ G + ++ I + V ++ L L++ +
Sbjct: 915 SFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTF 974
Query: 3730 KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMC 3789
K G P + G +VIET G+ V++D V + + +Y +C
Sbjct: 975 KAVARGPGGDPP-------YKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKGRVC 1026
Query: 3790 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKC 3849
GLCGN++ + +DF + S G+A EFGNSW+ P+CP A P D C
Sbjct: 1027 GLCGNFDDNAINDFATRSRSVVGDALEFGNSWK---------LSPSCPDALA---PKDPC 1074
Query: 3850 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNI 3907
+K ++ C +L PT ++C VD + C+ D C GG+ C+ +
Sbjct: 1075 TANPFRKSWAQKQCSILHGPT--FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAV 1132
Query: 3908 HAYVSACQAAGGHVEPWRNETFCPMEC----PQNS---HYELCADTCSLGCSALS----A 3956
AY AC AG V WR CP+ C P HY+ C C C S
Sbjct: 1133 AAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLV 1191
Query: 3957 PLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCY-HNGVYYEPEQTV-LIDNCRQQCTCH 4014
L +GC C F +N + QCGCY +G YY+ V +NC Q C
Sbjct: 1192 DLPGLEGCYPKCPPSQPF-FNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENC-QSCN-- 1247
Query: 4015 VGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT 4074
C PSG + C H + C YE
Sbjct: 1248 -----------------CTPSG--IQC-----AHSLE--------------ACTCTYEDR 1269
Query: 4075 CWLWGDPHYHSFDGRKFDFQGTC----NYVLATTGCPGVSTQGLTPFTVTT 4121
+ + D Y++ DG C + CPG T TPFT TT
Sbjct: 1270 TYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPG--TPATTPFTFTT 1318
Score = 360 bits (925), Expect = 2e-98
Identities = 353/1371 (25%), Positives = 510/1371 (37%), Gaps = 252/1371 (18%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 129
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 1792
V + A G + G V +NG LP S R + S + L ++
Sbjct: 130 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 182
Query: 1793 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAPGW 1849
+ WN + L Y CGLCG+ + P ++ + N L P +G + G
Sbjct: 183 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGP 240
Query: 1850 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 1909
C D C ++ G C G F CHA V ++ C D+
Sbjct: 241 TEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQDL 291
Query: 1910 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPS 1969
C C Y C AG +WR C TCP N ++ CGSPC +C +
Sbjct: 292 CRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 348
Query: 1970 PAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSEFW 2023
P +CE CV+GC C G ++ C+PL C C G + G+ F
Sbjct: 349 P---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTSF- 403
Query: 2024 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTL 2083
+ TCS C C GG C C C G H T
Sbjct: 404 -NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHISTY 439
Query: 2084 DGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 2142
D ++ G C Y+LS C +FTV G + + ++VTL +
Sbjct: 440 DEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA 494
Query: 2143 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LRVP 2200
+ + + ++ ++ LP ++ S +VV T GL L ++ +R+
Sbjct: 495 IRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 554
Query: 2201 AAYAGSLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 2255
A+ G +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 555 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLS 614
Query: 2256 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 2315
+ C ++ + + CH ++ P + C+ D C + LC A+++YV
Sbjct: 615 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 674
Query: 2316 ACQAAGAQLREWRRPDFCPF--QCPAHSHYELCGDSCPGSCPSLSAPEGCESAC---REG 2370
AC A G QL +WR + CP Y D+C +C LS + S +G
Sbjct: 675 ACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDG 734
Query: 2371 CVCDAG-FVLSGDTCVPVGQCGC------------LHDD---------RYYPLGQTFYPG 2408
C C AG F+ CVP +C C +HD+ + LG +
Sbjct: 735 CTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQKS 794
Query: 2409 PGCDSL-----CRCREGG-------------EVSCEPSSCGPHETCRP---SGGSLGCVA 2447
GC + C G +V C + C C P S GS GC+A
Sbjct: 795 TGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIA 854
Query: 2448 --------------------VGSTTCQ------------------ASGDPHYTTFDGRRF 2469
V TC A GD H+ TFDG R+
Sbjct: 855 EEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRY 914
Query: 2470 DFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQW 2528
F G+C Y+LAQ CG F ++ EN+ G + ++ I + V ++ L L++ +
Sbjct: 915 SFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTF 974
Query: 2529 KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMC 2588
K G P + G +VIET G+ V++D V + + +Y +C
Sbjct: 975 KAVARGPGGDPP-------YKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKGRVC 1026
Query: 2589 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEEC 2648
GLCGN++ + +DF + S G+A EFGNSW+ P+CP + P + C
Sbjct: 1027 GLCGNFDDNAINDFATRSRSVVGDALEFGNSWK---------LSPSCP---DALAPKDPC 1074
Query: 2649 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNI 2706
+K ++ C +L PT ++C VD + C+ D C GG+ C+ +
Sbjct: 1075 TANPFRKSWAQKQCSILHGPT--FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAV 1132
Query: 2707 HAYVSACQAAGGQVEPWRNETFCPMEC----PQNS---HYELCADTCSLGCSALS----A 2755
AY AC AG V WR CP+ C P HY+ C C C S
Sbjct: 1133 AAYAQACHDAGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLV 1191
Query: 2756 PLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCY-HNGAYYEPEQTV-LIDNCRQQCTCH 2813
L +GC C F +N + QCGCY +G YY+ V +NC Q C
Sbjct: 1192 DLPGLEGCYPKCPPSQPF-FNEDQMKCVAQCGCYDKDGNYYDVGARVPTAENC-QSCN-- 1247
Query: 2814 VGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT 2873
C PSG + C + C YE
Sbjct: 1248 -----------------CTPSG--IQCAH-------------------SLEACTCTYEDR 1269
Query: 2874 CWLWGDPHYHSFDGRKFDFQGTC----NYVLATTGCPGVSTQGLTPFTVTT 2920
+ + D Y++ DG C + CPG T TPFT TT
Sbjct: 1270 TYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPG--TPATTPFTFTT 1318
Score = 355 bits (910), Expect = 9e-97
Identities = 341/1316 (25%), Positives = 489/1316 (37%), Gaps = 218/1316 (16%)
Query: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134
C WGD HY +FDG F F G CNYV + F V + G+ V V
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEH-----CRAAYEDFNVQLRRGLVGSRPV--V 129
Query: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 4194
V + A G + G V +NG LP S R + S + L ++
Sbjct: 130 TRVVIKAQGLVLEASN---GSVLINGQREELPYS----RTGLLVEQSGDYIKVSIRLVLT 182
Query: 4195 YDWNWRVD--VTLPSSYHGAVCGLCGNMDRNPNNDQVFP-NGTLAPSIPIWGGSWRAPGW 4251
+ WN + L Y CGLCG+ + P ++ + N L P +G + G
Sbjct: 183 FLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQ--FGNLQKLDGP 240
Query: 4252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311
C D C ++ G C G F CHA V ++ C D+
Sbjct: 241 TEQCPDPLPLPAGNCTDEE-------GICHRTLLGPA--FAECHALVDSTAYLAACAQDL 291
Query: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371
C C Y C AG +WR C TCP N ++ CG PC +C +
Sbjct: 292 CRCP---TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSN 348
Query: 4372 PAPLTTPAVCEGPCVEGCQCDAGFV------LSADRCVPLNNGCGCWANGTYHEAGSEFW 4425
P +CE CV+GC C G ++ C+PL C C G + G+ F
Sbjct: 349 P---QRAQLCEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQ-CPCTHGGRTYSPGTSF- 403
Query: 4426 ADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTL 4485
+ TCS C C GG C C C G H T
Sbjct: 404 -NTTCSS-CTC--SGGLWQCQDLPC--------------------PGTCSVQGGAHISTY 439
Query: 4486 DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLT 4544
D +D G C Y+LS C +FTV G + + ++VTL +
Sbjct: 440 DEKLYDLHGDCSYVLSKKC-----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTA 494
Query: 4545 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVR--LRVP 4602
+ + + ++ ++ LP ++ S +VV T GL L ++ +R+
Sbjct: 495 IRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLD 554
Query: 4603 AAYAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPE 4657
A+ +CGLCGN+NQ+ ADD A+ G A AQ PC+
Sbjct: 555 PAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLS 614
Query: 4658 QQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVA 4717
+ C ++ + + CH ++ P + C+ D C + LC A+++YV
Sbjct: 615 VENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVH 674
Query: 4718 ACQAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESAC---RE 4771
AC A G QL +W R C CP Y D+C +C LS + S +
Sbjct: 675 ACAAKGVQLSDW-RDGVCTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVD 733
Query: 4772 GCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVFY---------------------- 4808
GC C AG F+ CVP +C C G GEV +
Sbjct: 734 GCTCPAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCTGGKLSCLGASLQK 793
Query: 4809 --------------------PGPECERRCE----------------CGPG------GHVT 4826
PG EC R C C PG G
Sbjct: 794 STGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCI 853
Query: 4827 CQEGAAC-------GPHEECRLEDGVQAC--------HATGCGRCLANGGIHYITLDGRV 4871
+E C P E R++ C H G C+A G H+IT DG
Sbjct: 854 AEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 913
Query: 4872 YDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVD 4930
Y GSC Y+LAQ C F IV E G T + + L +
Sbjct: 914 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTG----TTCSKAIKLFVESYELIL 969
Query: 4931 GEAVALPVAVG-----RVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 4985
E VA G ++ G +V++ T G+ + +D + + + ++GR+CGL
Sbjct: 970 QEGTFKAVARGPGGDPPYKIRYMGIFLVIE-THGMAVSWDRKTSVFIRLHQDYKGRVCGL 1028
Query: 4986 CGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYE 5045
CGNF+ N +DF + S FG +W+ S C + P+ C A
Sbjct: 1029 CGNFDDNAINDFATRSRSVVGDALEFGNSWKL---SPSCPDALAPK--DPCTANPFRKSW 1083
Query: 5046 SNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQA 5103
+ + C L P FA C++ + ++Y+ CV D CA GD C ++AAY AC
Sbjct: 1084 AQKQCSILHGP--TFAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHD 1141
Query: 5104 AGVAVKPWRTDSFCPLHCPAHS-------HYSICTRTCQGSC--------AALSGLTGCT 5148
AG+ V WRT CPL C ++ HY C C +C L GL GC
Sbjct: 1142 AGLCVS-WRTPDTCPLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCY 1200
Query: 5149 TRCFEGCECDDRFLLSQGVCIPVQDCGC-THNGRYLPVNSSLLTSDCSERCSCSSSSGLT 5207
+C F Q C V CGC +G Y V + + T++ + C+C + SG+
Sbjct: 1201 PKC---PPSQPFFNEDQMKC--VAQCGCYDKDGNYYDVGARVPTAENCQSCNC-TPSGIQ 1254
Query: 5208 C----QAAGCP-PGRVCEVKAEARNCWATRGLCVLSV-GANLTTFDGARGATTSPG 5257
C +A C R + N G C++++ G+N T R A PG
Sbjct: 1255 CAHSLEACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTII---RKAVACPG 1307
Score = 345 bits (886), Expect = 5e-94
Identities = 368/1423 (25%), Positives = 522/1423 (36%), Gaps = 301/1423 (21%)
Query: 1208 PGCDSLCHCQEGGLVSCESS---SCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFD 1264
P ++ H +GG + + S P PS L A C GD HY TFD
Sbjct: 31 PSWENAGHTMDGGAPTSSPTRRVSFVPPVTVFPSLSPLN-PAHNGRVCSTWGDFHYKTFD 89
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVIT-VQVANFTLRLE 1323
G F F G C YV ++ C R A NV G V V+T V + L LE
Sbjct: 90 GDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVVTRVVIKAQGLVLE 142
Query: 1324 QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 1383
V +NG +LP + + Q G + + L ++ + + Y
Sbjct: 143 ASNGSVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALLELDPKYA 200
Query: 1384 QQMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDSPCLPPTPCPPGSE 1439
Q CGLCG++NG P N A NA +FGN + P C P P P G+
Sbjct: 201 NQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGN- 254
Query: 1440 DCIPSHKCPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLKDCIFDLCLGGGNL 1498
C E E C + GP + CH LVD L C DLC
Sbjct: 255 -------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLAACAQDLCRCP--- 295
Query: 1499 SILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQC 1558
+ C+ Y C AGG WR CP CP N ++ C C+ CS C
Sbjct: 296 TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC 355
Query: 1559 QDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCT 1610
+D C +GC C G ++G C+P+ QC C H G Y P + + CT
Sbjct: 356 EDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPGTS--FNTTCSSCT 411
Query: 1611 CHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYE 1670
C SGG+ C PC G TC QGG
Sbjct: 412 C---------------------SGGLWQCQDL-PCPG-------TCSVQGGA-------- 434
Query: 1671 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG-NPAV 1729
H ++D + +D G C+YVL+ C S FTV + + G
Sbjct: 435 ---------HISTYDEKLYDLHGDCSYVLSKK-CADSS------FTVLAELRKCGLTDNE 478
Query: 1730 SYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGL 1789
+ ++ VT++ G + +I G V +N + T LP+S A+ + T + ++ GL
Sbjct: 479 NCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITL-FTPSSFFIVVQTGLGL 537
Query: 1790 QVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP 1847
Q+ +V V L ++ G +CGLCGN ++N +D +G + + + +W+A
Sbjct: 538 QLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQ 597
Query: 1848 GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVL 1907
+ C E+ E Y +C L F+ CH+ + P+ F C+
Sbjct: 598 AACANARNSFEDPCSLSVEN--ENY-ARHWCSRLTDPNSA-FSRCHSIINPKPFHSNCMF 653
Query: 1908 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI--TCPENSHYEVCGSPCPA 1965
D C D LC AL+SYV AC A GV + DWR V + CP++ Y C
Sbjct: 654 DTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQP 713
Query: 1966 SCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWA 2024
+C + V+GC C AG F+ A CVP C C+A+GT G
Sbjct: 714 TCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQE-CPCYAHGTVLAPGEVVHD 772
Query: 2025 DGTCSQWCRCGPGGGSLVCTPAS------------------------------------- 2047
+G C GG L C AS
Sbjct: 773 EGAV-----CSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDV 827
Query: 2048 ------CGLGEVC--GLLPSGQHGCQPVSTAEC------------------------QAW 2075
C G VC GL+ G GC C + W
Sbjct: 828 GCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRW 887
Query: 2076 GDPHYVTL--------------DGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 2121
H + L DG R++F+G+CEY+L+ G F + N
Sbjct: 888 ECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPC 947
Query: 2122 GSQAVSYTRSVTLQIYNHSLTLS-------ARW-----PRKLQVDGVFVTLPFQLDSLLH 2169
G+ + ++++ L + ++ L L AR P K++ G+F
Sbjct: 948 GTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPPYKIRYMGIF------------ 995
Query: 2170 AHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKP 2229
+V T G+++++D + V +R+ Y G +CGLCGN++ + +D
Sbjct: 996 --------LVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRS- 1046
Query: 2230 AGWQVGGAQGCGEC--VSKPCP------SPCTPEQQESFGGPDACGVISATDGP-LAPCH 2280
VG A G +S CP PCT C ++ GP A C
Sbjct: 1047 ---VVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL---HGPTFAACR 1100
Query: 2281 GLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCP 2338
V +Y++ C+ DAC G C AVA Y AC AG + WR PD CP C
Sbjct: 1101 SQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCD 1159
Query: 2339 AHS-------HYELCGDSCPGSC--PS------LSAPEGCESACREGCVCDAGFVLSGDT 2383
++ HY+ CG C +C PS L EGC C + + D
Sbjct: 1160 FYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP-----PSQPFFNEDQ 1214
Query: 2384 CVPVGQCGCL-HDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442
V QCGC D YY +G C S C C G + C S
Sbjct: 1215 MKCVAQCGCYDKDGNYYDVGARVPTAENCQS-CNCTPSG-IQCAHS-------------L 1259
Query: 2443 LGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGT 2485
C + D Y T DG +G C+ + + GT
Sbjct: 1260 EACTCTYEDRTYSYQDVIYNTTDG-----LGACLIAICGSNGT 1297
Score = 344 bits (882), Expect = 2e-93
Identities = 369/1405 (26%), Positives = 523/1405 (37%), Gaps = 289/1405 (20%)
Query: 3610 PGCDSLCRCREGGEVSCEPS---SCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFD 3666
P ++ +GG + P+ S P T PS L A C GD HY TFD
Sbjct: 31 PSWENAGHTMDGGAPTSSPTRRVSFVPPVTVFPSLSPLN-PAHNGRVCSTWGDFHYKTFD 89
Query: 3667 GHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVIT-VQVANFTLRLE 3725
G F F G C YV ++ C R A NV G V V+T V + L LE
Sbjct: 90 GDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVVTRVVIKAQGLVLE 142
Query: 3726 QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 3785
V +NG +LP + + Q G + + L ++ + + Y
Sbjct: 143 ASNGSVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALLELDPKYA 200
Query: 3786 QLMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDSPCLPPPTCPPGSA 3841
CGLCG++NG P N A NA +FGN + P C P P G+
Sbjct: 201 NQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGN- 254
Query: 3842 GCIPSDKCPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLKDCIFDLCLGGGNL 3900
C E E C + GP + CH LVD L C DLC
Sbjct: 255 -------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLAACAQDLCRCP--- 295
Query: 3901 SILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQC 3960
+ C+ Y C AGG WR CP CP N ++ C C+ CS C
Sbjct: 296 TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC 355
Query: 3961 PDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCT 4012
D C +GC C G ++G C+P+ QC C H G Y P + + CT
Sbjct: 356 EDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPGTS--FNTTCSSCT 411
Query: 4013 CHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYE 4072
C SGG+ C PC G TC QGG
Sbjct: 412 C---------------------SGGLWQCQDL-PCPG-------TCSVQGGA-------- 434
Query: 4073 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG-NPAV 4131
H ++D + +D G C+YVL+ C S FTV + + G
Sbjct: 435 ---------HISTYDEKLYDLHGDCSYVLSKK-CADSS------FTVLAELRKCGLTDNE 478
Query: 4132 SYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV-ADFG 4190
+ ++ VT++ G + +I G V +N + T LP+S A+ I++ +S ++V G
Sbjct: 479 NCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAAN--ITLFTPSSFFIVVQTGLG 536
Query: 4191 LQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRA 4248
LQ+ +V V L ++ G +CGLCGN ++N +D +G + + + +W+A
Sbjct: 537 LQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKA 596
Query: 4249 PGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCV 4308
+ C E+ E Y +C L+ F+ CH+ + P+ F C+
Sbjct: 597 QAACANARNSFEDPCSLSVEN--ENY-ARHWCSRLTDPNSA-FSRCHSIINPKPFHSNCM 652
Query: 4309 LDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI--TCPENSHYEVCGPPCP 4366
D C D LC AL+SYV AC A GV + DWR V + CP++ Y C
Sbjct: 653 FDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQ 712
Query: 4367 ASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFW 4425
+C + V+GC C AG F+ A CVP C C+A+GT G
Sbjct: 713 PTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQE-CPCYAHGTVLAPGEVVH 771
Query: 4426 ADGTCSQWCRCGPGGGSLVCTPAS------------------------------------ 4449
+G C GG L C AS
Sbjct: 772 DEGAV-----CSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLD 826
Query: 4450 -------CGLGEVC--GLLPSGQHGCQPVSTAEC------------------------QA 4476
C G VC GL+ G GC C +
Sbjct: 827 VGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRR 886
Query: 4477 WGDPHYVTL--------------DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEH 4522
W H + L DG R+ F+G+CEY+L+ G F + N
Sbjct: 887 WECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIP 946
Query: 4523 RGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVAL--------PFQLDSLLHAHL 4574
G+ + ++++ L + ++ L L +G F A+ P+++ +
Sbjct: 947 CGTTGTTCSKAIKLFVESYELILQ---------EGTFKAVARGPGGDPPYKIRYM----- 992
Query: 4575 SGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGW 4634
+V T G+++++D + V +R+ Y +CGLCGN++ + +D
Sbjct: 993 --GIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRS---- 1046
Query: 4635 QVGGAQGCGEC--VSKPCP------SPCTPEQQESFGGPDACGVISATDGP-LAPCHGLV 4685
VG A G +S CP PCT C ++ GP A C V
Sbjct: 1047 VVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL---HGPTFAACRSQV 1103
Query: 4686 PPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS 4743
+Y++ C+ DAC G C AVA Y AC AG + WR PD CPL C ++
Sbjct: 1104 DSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCDFYN 1162
Query: 4744 -------HYELCGDSCPVSC--PS------LSAPEGCESACREGCVCDAGFVLSGDTCVP 4788
HY+ CG C +C PS L EGC C + + D
Sbjct: 1163 PHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP-----PSQPFFNEDQMKC 1217
Query: 4789 VGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECR------- 4840
V QCGC DG YY +G C+ C C P G AC E R
Sbjct: 1218 VAQCGCYDKDGNYYDVGARVPTAENCQ-SCNCTPSGIQCAHSLEACTCTYEDRTYSYQDV 1276
Query: 4841 ---LEDGVQACHATGCGRCLANGGI 4862
DG+ AC CG +NG I
Sbjct: 1277 IYNTTDGLGACLIAICG---SNGTI 1298
Score = 341 bits (875), Expect = 1e-92
Identities = 368/1423 (25%), Positives = 521/1423 (36%), Gaps = 301/1423 (21%)
Query: 2409 PGCDSLCRCREGGEVSCEPS---SCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFD 2465
P ++ +GG + P+ S P T PS L A C GD HY TFD
Sbjct: 31 PSWENAGHTMDGGAPTSSPTRRVSFVPPVTVFPSLSPLN-PAHNGRVCSTWGDFHYKTFD 89
Query: 2466 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVIT-VQVANFTLRLE 2524
G F F G C YV ++ C R A NV G V V+T V + L LE
Sbjct: 90 GDVFRFPGLCNYVFSEHC-------RAAYEDFNVQLRRGLVGSRPVVTRVVIKAQGLVLE 142
Query: 2525 QRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYY 2584
V +NG +LP + + Q G + + L ++ + + Y
Sbjct: 143 ASNGSVLINGQREELPY--SRTGLLVEQSGDYIKVSIRLVLTFLWNGEDSALLELDPKYA 200
Query: 2585 QLMCGLCGNYNGDPKDDFQKPNGSQAGNAN----EFGNSWEEVVPDSPCLPPPTCPPGSE 2640
CGLCG++NG P N A NA +FGN + P C P P G+
Sbjct: 201 NQTCGLCGDFNGLPAF-----NEFYAHNARLTPLQFGNLQKLDGPTEQCPDPLPLPAGN- 254
Query: 2641 GCIPSEECPPELEKKYQKEEFCGLLSSPTGP-LSSCHKLVDPQGPLKDCIFDLCLGGGNL 2699
C E E C + GP + CH LVD L C DLC
Sbjct: 255 -------CTDE-------EGICH--RTLLGPAFAECHALVDSTAYLAACAQDLCRCP--- 295
Query: 2700 SILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQC 2759
+ C+ Y C AGGQ WR CP CP N ++ C C+ CS C
Sbjct: 296 TCPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQLC 355
Query: 2760 PDGCAEGCQCDSG--------FLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCT 2811
D C +GC C G ++G C+P+ QC C H G Y P + + CT
Sbjct: 356 EDHCVDGCFCPPGRSCTVLDDITHSG--CLPLGQCPCTHGGRTYSPGTS--FNTTCSSCT 411
Query: 2812 CHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYE 2871
C SGG+ C + PC G TC QGG
Sbjct: 412 C---------------------SGGLWQCQDL-PCPG-------TCSVQGGA-------- 434
Query: 2872 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG-NPAV 2930
H ++D + +D G C+YVL+ C S FTV + + G
Sbjct: 435 ---------HISTYDEKLYDLHGDCSYVLSKK-CADSS------FTVLAELRKCGLTDNE 478
Query: 2931 SYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGL 2990
+ ++ VT++ G + +I G V +N + T LP+S A+ + T + ++ GL
Sbjct: 479 NCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITL-FTPSSFFIVVQTGLGL 537
Query: 2991 QVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAP 3048
Q+ +V V L ++ G +CGLCGN ++N +D +G + + + +W+A
Sbjct: 538 QLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQ 597
Query: 3049 GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVL 3108
+ C E+ E Y +C L F+ CH+ + P+ F C+
Sbjct: 598 AACANARNSFEDPCSLSVEN--ENY-ARHWCSRLTDPNSA-FSRCHSIINPKPFHSNCMF 653
Query: 3109 DVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI--TCPENSHYEVCGPPCPA 3166
D C D LC AL+SYV AC A GV + DWR V + CP++ Y C
Sbjct: 654 DTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCPKSQRYAYVVDACQP 713
Query: 3167 SCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWA 3225
+C + V+GC C AG F+ A CVP C C+A+GT G
Sbjct: 714 TCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQE-CPCYAHGTVLAPGEVVHD 772
Query: 3226 DGTCSQWCRCGPGGGSLVCTPAS------------------------------------- 3248
+G C GG L C AS
Sbjct: 773 EGAV-----CSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDV 827
Query: 3249 ------CGLGEVC--GLLPSGQHGCQPVSTAEC------------------------QAW 3276
C G VC GL+ G GC C + W
Sbjct: 828 GCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRW 887
Query: 3277 GDPHYVTL--------------DGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHR 3322
H + L DG R+ F+G+CEY+L+ G F + N
Sbjct: 888 ECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPC 947
Query: 3323 GSQAVSYTRSVTLQIYNHSLTLS-------ARW-----PRKLQVDGVFVTLPFQLDSLLH 3370
G+ + ++++ L + ++ L L AR P K++ G+F
Sbjct: 948 GTTGTTCSKAIKLFVESYELILQEGTFKAVARGPGGDPPYKIRYMGIF------------ 995
Query: 3371 AHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKP 3430
+V T G+++++D + V +R+ Y G +CGLCGN++ + +D
Sbjct: 996 --------LVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATRSRS- 1046
Query: 3431 AGWQVGGAQGCGEC--VSKPCP------SPCTPEQQESFGGPDACGVISATDGP-LAPCH 3481
VG A G +S CP PCT C ++ GP A C
Sbjct: 1047 ---VVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSIL---HGPTFAACR 1100
Query: 3482 GLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCP 3539
V +Y++ C+ DAC G C AVA Y AC AG + WR PD CP C
Sbjct: 1101 SQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCD 1159
Query: 3540 AHS-------HYELCGDSCPGSC--PS------LSAPEGCESACREGCVCDAGFVLSGDT 3584
++ HY+ CG C +C PS L EGC C + + D
Sbjct: 1160 FYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCP-----PSQPFFNEDQ 1214
Query: 3585 CVPVGQCGCL-HDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643
V QCGC D YY +G C S C C G + C S
Sbjct: 1215 MKCVAQCGCYDKDGNYYDVGARVPTAENCQS-CNCTPSG-IQCAHS-------------L 1259
Query: 3644 LGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGT 3686
C + D Y T DG +G C+ + + GT
Sbjct: 1260 EACTCTYEDRTYSYQDVIYNTTDG-----LGACLIAICGSNGT 1297
Score = 306 bits (785), Expect = 3e-82
Identities = 283/1040 (27%), Positives = 398/1040 (38%), Gaps = 206/1040 (19%)
Query: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 4533
C WGD HY T DG F F G C Y+ S C E+F V + GS+ V TR
Sbjct: 77 CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRA---AYEDFNVQLRRGLVGSRPV-VTRV 132
Query: 4534 VTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 4593
V I L L A L ++G LP+ LL SG + V+ L+ ++G
Sbjct: 133 V---IKAQGLVLEASNGSVL-INGQREELPYSRTGLL-VEQSGDYIKVSIRLVLTFLWNG 187
Query: 4594 DSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQ---GCGECVSKP 4649
+ L + YA CGLCG++N PA ++ A + Q G Q G E P
Sbjct: 188 EDSALLELDPKYANQTCGLCGDFNGLPAFNEFYAHNARLTPLQFGNLQKLDGPTEQCPDP 247
Query: 4650 CPSP---CTPEQQESFGGPDACGVISATD-GP-LAPCHGLVPPAQYFQGCLLDACQVQGH 4704
P P CT E+ G+ T GP A CH LV Y C D C+
Sbjct: 248 LPLPAGNCTDEE----------GICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPTC 297
Query: 4705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 4764
P C Y C AG Q WR P+ CP CP + ++ CG C +C + +
Sbjct: 298 P---CATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECGSPCTDTCSNPQRAQL 354
Query: 4765 CESACREGCVCDAG---FVLSGDT---CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818
CE C +GC C G VL T C+P+GQC C H GR Y G F
Sbjct: 355 CEDHCVDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTYSPGTSF----------- 403
Query: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 4877
+ TC C G+ C C G C GG H T D ++YDLHG
Sbjct: 404 -----NTTCSS---------CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGD 449
Query: 4878 CSYVLAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVAGQVVSLAQGQQVTVDGEA-- 4933
CSYVL++ C D F+++ E G D + L V + +V DG
Sbjct: 450 CSYVLSKKC----ADSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFL 505
Query: 4934 ----VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLC 4986
LP++ + + T +V+QT GL+LL + + + +G++CGLC
Sbjct: 506 NSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLC 565
Query: 4987 GNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYES 5046
GNFN N +DDF +G ++ F W+A + C P L+ E Y +
Sbjct: 566 GNFNQNQADDFTALSGVVEATGAAFANTWKAQAA---CANARNSFEDPCSLSVENENY-A 621
Query: 5047 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 5106
C +L +P F+ C ++++P + C++D C + + LC +L++Y AC A GV
Sbjct: 622 RHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 681
Query: 5107 AVKPWRTDSFCPLH---CPAHSHYSICTRTCQGSCAALSGLTGCTTRC------FEGCEC 5157
+ WR D C + CP Y+ CQ +C GL+ C +GC C
Sbjct: 682 QLSDWR-DGVCTKYMQNCPKSQRYAYVVDACQPTCR---GLSEADVTCSVSFVPVDGCTC 737
Query: 5158 D-DRFLLSQGVCIPVQD----------------------CGCTHNGRYLPVNSSLLTS-- 5192
FL G C+P Q+ C CT G+ + +SL S
Sbjct: 738 PAGTFLNDAGACVPAQECPCYAHGTVLAPGEVVHDEGAVCSCT-GGKLSCLGASLQKSTG 796
Query: 5193 --------DCSERCS--------------------------CSSSSGLTCQAAG------ 5212
DCS + C GL +G
Sbjct: 797 CAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEE 856
Query: 5213 -CP---------PGRVCEVKAEARNCWATR---------GLCVLSVGANLTTFDGARGAT 5253
CP PG V C R G CV + TFDG R +
Sbjct: 857 DCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSF 916
Query: 5254 TSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWV 5313
Y L+ G T +R+V E C G T +K + +
Sbjct: 917 EGSCEYILAQDYCGDNTTHGTFRIVTENIPC----------------GTTGTTCSKAIKL 960
Query: 5314 NGLRVDLPAEKLASVSVSRTPDGS----------LLVRQKAGVQVWLGANGKVAVIVSND 5363
+L ++ +V+R P G LV + G+ V V + + D
Sbjct: 961 FVESYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQD 1020
Query: 5364 HAGKLCGACGNFDGDQTNDW 5383
+ G++CG CGNFD + ND+
Sbjct: 1021 YKGRVCGLCGNFDDNAINDF 1040
Score = 251 bits (640), Expect = 2e-65
Identities = 246/946 (26%), Positives = 369/946 (39%), Gaps = 174/946 (18%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C GG C C QG H +T+D + YD+ G CSY + + C++ +F+V
Sbjct: 410 CTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADS----SFTV 465
Query: 514 EAKNEHRG-SRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
A+ G + + + VT+ ++ G V +++ ++LP+S + L
Sbjct: 466 LAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFT-P 524
Query: 573 SGPRAVVELVFGLVVTYDWD--CQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 630
S VV+ GL + Q+ + L Q Q+CGLCGN+N + ADDF G +
Sbjct: 525 SSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVE 584
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCH 688
FA++WK + ++ C + A+H+ C LT + F+ CH
Sbjct: 585 ATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHW-----CSRLTDPNSAFSRCH 639
Query: 689 DTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP--ANCPLSCP 746
++P+PF C++D C LC LS+Y AC G+ + DWR +CP
Sbjct: 640 SIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDWRDGVCTKYMQNCP 699
Query: 747 ANSRYELCGPACPTSCNG-AAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTF 803
+ RY AC +C G + A CS V+GC C G F+ GACVPA C C
Sbjct: 700 KSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYA 759
Query: 804 QGLQLAPGQEVWADELCQRRCT-----CNGATHQ-----------VTCRDKQSCPAGERC 847
G LAPG EV DE CT C GA+ Q + C + + G C
Sbjct: 760 HGTVLAPG-EVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAEC 818
Query: 848 -------------------------SVQNGLLGCYPDRFGTCQGSG-----------DPH 871
V +G GC + C + D +
Sbjct: 819 LRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCN 878
Query: 872 YVSFDGRRFD-----FMGTCT--------------YLLVGS---------CGQNAALPAF 903
+ RR++ +GTC Y GS CG N F
Sbjct: 879 TCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTF 938
Query: 904 RVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA------AD 957
R++ EN G+ + ++A+++ ++ +LQ F+A D
Sbjct: 939 RIVTENIPCGTTGTTCSKAIKLFVESYEL--------------ILQEGTFKAVARGPGGD 984
Query: 958 GQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
++ G V+ T G+ V++D V ++ Y +CGLCGNF+ + +D A R
Sbjct: 985 PPYKIRYMGIFLVIET-HGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDFATR 1043
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQ---SKNECGILADPKGP 1074
+AL FGNSW + P C P D A + ++ +C IL P
Sbjct: 1044 SRSVVGDALEFGNSW--KLSPSC----PDALAPKDPCTANPFRKSWAQKQCSILHGP--T 1095
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELC 1132
F C S++D CV D C G C A+A YA AC AG V WR+ + C
Sbjct: 1096 FAACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTC 1154
Query: 1133 PLSCP---PHS----HYEACSYGCPLSCGD------LPVPGGCGSECHEGCVCDEGFALS 1179
PL C PH HY+ C C +C + + +PG G C+ C + F +
Sbjct: 1155 PLFCDFYNPHGGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEG--CYPKCPPSQPF-FN 1211
Query: 1180 GESCLPLASCGCVHQ-GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPS 1238
+ +A CGC + G Y+ G C S C+C G+ S
Sbjct: 1212 EDQMKCVAQCGCYDKDGNYYDVGARVPTAENCQS-CNCTPSGIQCAHSLE---------- 1260
Query: 1239 GGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGT 1284
C + D Y T DG +G C+ + + GT
Sbjct: 1261 ----ACTCTYEDRTYSYQDVIYNTTDG-----LGACLIAICGSNGT 1297
Score = 125 bits (315), Expect = 9e-28
Identities = 185/761 (24%), Positives = 259/761 (34%), Gaps = 154/761 (20%)
Query: 2871 EATCWLWGDPHYHSFDGRKFDFQGTCNYVL-----ATTGCPGVSTQGLTPFTVTTKNQNR 2925
E C +WG HY +FDG + F+G C YVL A G + T R
Sbjct: 5075 ECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAR 5134
Query: 2926 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 2985
A+S + ++ + T +H E G + + + + S +SV + + +
Sbjct: 5135 CPRALS-IHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5193
Query: 2986 ADFGLQVSYDWNWRV-DVTLPSS-YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 3043
G+ V++ N +V LP S +H G CG N +D + +GT A S
Sbjct: 5194 PALGVSVTF--NGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAK 5251
Query: 3044 SWRAP-GWDPLCWDECRGSCPTC-PEDRLEQYEGPGFCGPLAPGT---GGPFTTCHAHVP 3098
+W P CW G+ PT P + P C P F CH VP
Sbjct: 5252 TWLVPDSRKDGCWAPT-GTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVP 5310
Query: 3099 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG--CEITCPENSH 3156
P FF C+ D C G ++ C++L +Y C+A GV DWR G C++TCP
Sbjct: 5311 PGPFFNACISDHCRGR--LEVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLTCPPTKV 5367
Query: 3157 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 3216
Y+ CGP PA+C S EG EGC C +L C C +
Sbjct: 5368 YKPCGPIQPATCNS---RNQSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGF 5423
Query: 3217 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL----------GEVCGLLPSGQHGCQ 3266
+ E W Q C C G S+ C P C G V P ++ C
Sbjct: 5424 PKFPGERWVSN--CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCC 5481
Query: 3267 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 3326
P + C TC L C P G E ++ + G
Sbjct: 5482 PETVCVCNT-----------------TTCPQSLPV-C---PPGQE----SICTQEEGDCC 5516
Query: 3327 VSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGL 3386
++ L YN + GV T P L + LSG T
Sbjct: 5517 PTFRCRPQLCSYNGTFY------------GVGATFPGALPCHMCTCLSG------DTQDP 5558
Query: 3387 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVS 3446
++ D+ C N + K V G Q CGECV
Sbjct: 5559 TVQCQEDA-----------------CNNTTCPQGFEYKRVAG----------QCCGECVQ 5591
Query: 3447 KPCPSP------------------CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQ 3488
C +P CT E+ GG A+ ++ C G +
Sbjct: 5592 TACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTG 5651
Query: 3489 YFQGCLLDACQVQ------GHPG-----------GLCPAVATYVAACQAAGAQ---LREW 3528
C D+CQV+ H G G CP + Y A QA Q +E
Sbjct: 5652 CCYSCEEDSCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQER 5711
Query: 3529 R-RPDFCPFQCP-------AHSHYELCGDSCPGSCPSLSAP 3561
R + P CP ++H + CG P P+ AP
Sbjct: 5712 RVHEETVPLHCPNGSAILHTYTHVDECG-CTPFCVPAPMAP 5751
Score = 122 bits (307), Expect = 7e-27
Identities = 184/761 (24%), Positives = 258/761 (33%), Gaps = 154/761 (20%)
Query: 1670 EATCWLWGDPHYHSFDGRKFDFQGTCNYVL-----ATTGCPGVSTQGLTPFTVTTKNQNR 1724
E C +WG HY +FDG + F+G C YVL A G + T R
Sbjct: 5075 ECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAR 5134
Query: 1725 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 1784
A+S + ++ + T +H E G + + + + S +SV + + +
Sbjct: 5135 CPRALS-IHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5193
Query: 1785 ADFGLQVSYDWNWRV-DVTLPSS-YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1842
G+ V++ N +V LP S +H G CG N +D + +GT A S
Sbjct: 5194 PALGVSVTF--NGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAK 5251
Query: 1843 SWRAP-GWDPLCWDECRGSCPTC-PEDRLEQYEGPGFCGPLAPGT---GGPFTTCHAHVP 1897
+W P CW G+ PT P + P C P F CH VP
Sbjct: 5252 TWLVPDSRKDGCWAPT-GTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVP 5310
Query: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG--CEITCPENSH 1955
P FF C+ D C G ++ C++L +Y C+A G V DWR G C++TCP
Sbjct: 5311 PGPFFNACISDHCR--GRLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKV 5367
Query: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015
Y+ CG PA+C S EG EGC C +L C C +
Sbjct: 5368 YKPCGPIQPATCNS---RNQSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGF 5423
Query: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL----------GEVCGLLPSGQHGCQ 2065
+ E W Q C C G S+ C P C G V P ++ C
Sbjct: 5424 PKFPGERWVSN--CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCC 5481
Query: 2066 PVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 2125
P + C TC L C P G E ++ + G
Sbjct: 5482 PETVCVCNT-----------------TTCPQSLPV-C---PPGQE----SICTQEEGDCC 5516
Query: 2126 VSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGL 2185
++ L YN + GV T P L + LSG T
Sbjct: 5517 PTFRCRPQLCSYNGTFY------------GVGATFPGALPCHMCTCLSG------DTQDP 5558
Query: 2186 SLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVS 2245
++ D+ C N + K V G Q CGECV
Sbjct: 5559 TVQCQEDA-----------------CNNTTCPQGFEYKRVAG----------QCCGECVQ 5591
Query: 2246 KPCPSP------------------CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQ 2287
C +P CT E+ GG A+ ++ C G +
Sbjct: 5592 TACLTPDGQPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTG 5651
Query: 2288 YFQGCLLDACQVQ------GHPG-----------GLCPAVATYVAACQAAGAQ---LREW 2327
C D+CQV+ H G G CP + Y A QA Q +E
Sbjct: 5652 CCYSCEEDSCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQER 5711
Query: 2328 R-RPDFCPFQCP-------AHSHYELCGDSCPGSCPSLSAP 2360
R + P CP ++H + CG P P+ AP
Sbjct: 5712 RVHEETVPLHCPNGSAILHTYTHVDECG-CTPFCVPAPMAP 5751
Score = 121 bits (304), Expect = 2e-26
Identities = 116/427 (27%), Positives = 164/427 (38%), Gaps = 37/427 (8%)
Query: 4072 EATCWLWGDPHYHSFDGRKFDFQGTCNYVL-----ATTGCPGVSTQGLTPFTVTTKNQNR 4126
E C +WG HY +FDG + F+G C YVL A G + T R
Sbjct: 5075 ECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAR 5134
Query: 4127 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV 4186
A+S + ++ + T +H E G + + + + S +SV + + +
Sbjct: 5135 CPRALS-IHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDI 5193
Query: 4187 ADFGLQVSYDWNWRV-DVTLPSS-YHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 4244
G+ V++ N +V LP S +H G CG N +D + +GT A S
Sbjct: 5194 PALGVSVTF--NGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAK 5251
Query: 4245 SWRAP-GWDPLCWDECRGSCPTC-PEDRLEQYEGPGFCGP---LSSGTGGPFTTCHAHVP 4299
+W P CW G+ PT P + P C P F CH VP
Sbjct: 5252 TWLVPDSRKDGCWAPT-GTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVP 5310
Query: 4300 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVG--CEITCPENSH 4357
P FF C+ D C G ++ C++L +Y C+A GV DWR G C++TCP
Sbjct: 5311 PGPFFNACISDHCRGR--LEVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLTCPPTKV 5367
Query: 4358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 4417
Y+ CGP PA+C S EG EGC C +L C C +
Sbjct: 5368 YKPCGPIQPATCNS---RNQSPQLEG-MAEGCFCPEDQILFNAHMGICVQACPCVGPDGF 5423
Query: 4418 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGL----------GEVCGLLPSGQHGCQ 4467
+ E W Q C C G S+ C P C G V P ++ C
Sbjct: 5424 PKFPGERWVSN--CQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTRPRAENPCC 5481
Query: 4468 PVSTAEC 4474
P + C
Sbjct: 5482 PETVCVC 5488
Score = 120 bits (301), Expect = 4e-26
Identities = 126/497 (25%), Positives = 182/497 (36%), Gaps = 94/497 (18%)
Query: 1222 VSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 1281
VS S C H C+ C+ C G HY+TFDG + F G C YVL +
Sbjct: 5061 VSDPSQPCDFHYECE-------CI------CSMWGGSHYSTFDGTSYTFRGNCTYVLMRE 5107
Query: 1282 CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVV 1341
R G + L + + + R R + +D+ L V
Sbjct: 5108 IHARFG-NLSLYLDNHYCTASATAAAARC-------------PRALSIHYKSMDIVLTVT 5153
Query: 1342 LANGQIRASQHGSDVVIETDF---GLRVAYDLVYYVRVTVP---------GNYYQQMC-- 1387
+ +G+ + + + F G+ V+ +RV +P G +Q
Sbjct: 5154 MVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPY 5213
Query: 1388 --------GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP---CLPPTPCPP 1436
G CG + +DD + +G+ A + + +W +VPDS C PT PP
Sbjct: 5214 SLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPP 5271
Query: 1437 GSEDCIPSHK------CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFD 1490
+ P CPP+ C L+ S + CH LV P CI D
Sbjct: 5272 TASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQV--FAECHNLVPPGPFFNACISD 5321
Query: 1491 LCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTET--FCPMECPPNSHYELCADTCSLG 1548
C G L + C ++ AY C+A G WR T C + CPP Y+ C
Sbjct: 5322 HCRG--RLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPAT 5378
Query: 1549 CSALSAPPQCQDGCAEGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQ 1607
C++ + PQ +G AEGC C + L+N + +Q C C + + + NC Q
Sbjct: 5379 CNSRNQSPQL-EGMAEGCFCPEDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-Q 5436
Query: 1608 QCTCHAGKGMVCQEHSCKPGQVCQPSGGILSC-------VTK----DPCHGVTCRPQETC 1656
C C G V CKP C G C VT+ +PC T T
Sbjct: 5437 SCVCDEGSVSV----QCKP-LPCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTT 5491
Query: 1657 KEQGGQGVCLPNYEATC 1673
VC P E+ C
Sbjct: 5492 TCPQSLPVCPPGQESIC 5508
Score = 116 bits (291), Expect = 5e-25
Identities = 140/596 (23%), Positives = 207/596 (34%), Gaps = 121/596 (20%)
Query: 2337 CPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 2391
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 4976 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5025
Query: 2392 -------CLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS-CGPHETCRPSGGSL 2443
C+ D+R L P P + C + +PS C H C
Sbjct: 5026 ENCTVARCVGDNRVVLLD----PKPVANVTCVNKHLPIKVSDPSQPCDFHYECE------ 5075
Query: 2444 GCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGN 2503
C+ C G HY+TFDG + F G C YVL + R G + L + +
Sbjct: 5076 -CI------CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFG-NLSLYLDNHYCTAS 5127
Query: 2504 GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF 2563
+ R R + +D+ L V + +G+ + + + F
Sbjct: 5128 ATAAAARC-------------PRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGF 5174
Query: 2564 ---GLRVAYDLVYYVRVTVP---------GNYYQLMC----------GLCGNYNGDPKDD 2601
G+ V+ +RV +P G +Q G CG + +DD
Sbjct: 5175 SKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDD 5234
Query: 2602 FQKPNGSQAGNANEFGNSWEEVVPDS---PCLPPPTCPPGSEGCIPSEE------CPPEL 2652
+ +G+ A + + +W +VPDS C P PP + P CPP
Sbjct: 5235 CLQRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPP-- 5290
Query: 2653 EKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSA 2712
+ C L+ S + CH LV P CI D C G L + C ++ AY
Sbjct: 5291 ------QPLCDLMLSQV--FAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAEL 5340
Query: 2713 CQAAGGQVEPWRNET--FCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQC- 2769
C+A G WR T C + CP Y+ C C++ + Q +G AEGC C
Sbjct: 5341 CRAR-GVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQL-EGMAEGCFCP 5398
Query: 2770 DSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 2829
+ L+N + +Q C C + + + NC Q C C G V V CKP
Sbjct: 5399 EDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSV----QCKP-L 5452
Query: 2830 VCQPSGGILSCVN-----------KDPCHGVTCRPQETCKEQGGQGVCLPNYEATC 2874
C G C ++PC T T VC P E+ C
Sbjct: 5453 PCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESIC 5508
Score = 115 bits (289), Expect = 9e-25
Identities = 142/596 (23%), Positives = 210/596 (35%), Gaps = 121/596 (20%)
Query: 3538 CPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 3592
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 4976 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5025
Query: 3593 -------CLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS-CGPHETCRPSGGSL 3644
C+ D+R L P P + C + +PS C H C
Sbjct: 5026 ENCTVARCVGDNRVVLLD----PKPVANVTCVNKHLPIKVSDPSQPCDFHYECE------ 5075
Query: 3645 GCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGN 3704
C+ C G HY+TFDG + F G C YVL + R G + L + +
Sbjct: 5076 -CI------CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFG-NLSLYLDNHYCTAS 5127
Query: 3705 GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDF 3764
+ R R + +D+ L V + +G+ + + + F
Sbjct: 5128 ATAAAARC-------------PRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGF 5174
Query: 3765 ---GLRVAYDLVYYVRVTVP---------GNYYQLMC----------GLCGNYNGDPKDD 3802
G+ V+ +RV +P G +Q G CG + +DD
Sbjct: 5175 SKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDD 5234
Query: 3803 FQKPNGSQAGNANEFGNSWEEVVPDS---PCLPPPTCPPGSAGCIPSDK------CPPEL 3853
+ +G+ A + + +W +VPDS C P PP ++ P CPP
Sbjct: 5235 CLQRDGTTAASCKDMAKTW--LVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPP-- 5290
Query: 3854 EKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSA 3913
+ C L+ S + CH LV P CI D C G L + C ++ AY
Sbjct: 5291 ------QPLCDLMLSQV--FAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAEL 5340
Query: 3914 CQAAGGHVEPWRNET--FCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQC- 3970
C+A G WR T C + CP Y+ C C++ + Q +G AEGC C
Sbjct: 5341 CRAR-GVCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQL-EGMAEGCFCP 5398
Query: 3971 DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 4030
+ L+N + +Q C C + + + NC Q C C G V V CKP
Sbjct: 5399 EDQILFNAHMGICVQACPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSV----QCKP-L 5452
Query: 4031 VCQPSGGILSC-------VTK----DPCHGVTCRPQETCKEQGGQGVCLPNYEATC 4075
C G C VT+ +PC T T VC P E+ C
Sbjct: 5453 PCDAQGQPPPCNRPGFVTVTRPRAENPCCPETVCVCNTTTCPQSLPVCPPGQESIC 5508
Score = 115 bits (288), Expect = 1e-24
Identities = 113/405 (27%), Positives = 161/405 (39%), Gaps = 62/405 (15%)
Query: 467 ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM----------VELCSEDDTLPAFSVEAK 516
E +C G HY+TFDG Y G C+Y + + L ++ A + A
Sbjct: 5073 ECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAA 5132
Query: 517 NEHRGSRRVSYVGLVTVRAYSHSVSLTRG-EVGFVLVDNQRSRLPVS--LSEGRLRVYQS 573
+ + Y + V +V++ G E G +L D ++PVS S+ + V
Sbjct: 5133 ARCPRALSIHYKSMDIVL----TVTMVHGKEEGLILFD----QIPVSSGFSKNGVLVSVL 5184
Query: 574 GPRAV-VEL-VFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
G + V++ G+ VT++ A + F + G CG + DD L DG A
Sbjct: 5185 GTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAA 5244
Query: 632 DAVEFASSWKLDDGDYLCEDGC---------------QNNCPACTPGQAQHYEGDRLCGM 676
+ A +W + D +DGC ++ P TP Q LC +
Sbjct: 5245 SCKDMAKTWLVPDSR---KDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQ-----PLCDL 5296
Query: 677 LTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWR 736
+ L FA CH+ + P PF C+ D C G C+ L AYA+ C G+ DWR
Sbjct: 5297 M--LSQVFAECHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGV-CSDWR 5351
Query: 737 SPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG---FVASGG 791
C L+CP Y+ CGP P +CN G EGC C F A G
Sbjct: 5352 GATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQSPQLEG--MAEGCFCPEDQILFNAHMG 5409
Query: 792 ACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCR 836
CV A C G PG E W CQ C C+ + V C+
Sbjct: 5410 ICVQACPC-VGPDGFPKFPG-ERWVSN-CQ-SCVCDEGSVSVQCK 5450
Score = 110 bits (276), Expect = 3e-23
Identities = 135/554 (24%), Positives = 193/554 (34%), Gaps = 98/554 (17%)
Query: 4739 CPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCG----- 4793
C H + +CP S P +S+ + GC D +P+ Q
Sbjct: 4976 CNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGC----------DNAIPLRQVNETWTL 5025
Query: 4794 -------CLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQ 4846
C+ D R L + P +VTC H ++ D Q
Sbjct: 5026 ENCTVARCVGDNRVVLL--------------DPKPVANVTC-----VNKHLPIKVSDPSQ 5066
Query: 4847 ACHATGCGRCLAN--GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPG------DEDFSIV 4898
C C+ + GG HY T DG Y G+C+YVL + H + G D +
Sbjct: 5067 PCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTA 5126
Query: 4899 LEKNAAGDLQRLLVTVAGQV-----VSLAQGQQ---VTVDGEAVALPVAVGRVRVTAEGR 4950
AA R L + V++ G++ + D V+ + V V+ G
Sbjct: 5127 SATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGT 5186
Query: 4951 NMVLQTTK--GLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSV 5008
+ G+ + F+G S F G CG N DD + +G+ A+S
Sbjct: 5187 TTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASC 5246
Query: 5009 ETFGAAWRAPGSSK-GCGEGCG-----PQGCPVCLAEETAPYESNEACGQLRNPQGPFAT 5062
+ W P S K GC G PV P C + + FA
Sbjct: 5247 KDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQ--VFAE 5304
Query: 5063 CQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWR--TDSFCPLH 5120
C ++ P +F C+ D C +G C+SL AY C+A GV WR T C L
Sbjct: 5305 CHNLVPPGPFFNACISDHC--RGRLEVPCQSLEAYAELCRARGVC-SDWRGATGGLCDLT 5361
Query: 5121 CPAHSHYSICTRTCQGSCAA------LSGLTGCTTRCFEGCEC-DDRFLLSQGVCIPVQD 5173
CP Y C +C + L G+ EGC C +D+ L + + I VQ
Sbjct: 5362 CPPTKVYKPCGPIQPATCNSRNQSPQLEGMA-------EGCFCPEDQILFNAHMGICVQA 5414
Query: 5174 CGCTHNGRYLPVNSSLLTSDCSERCSCSSSS------GLTCQAAGCP-----PGRVCEVK 5222
C C + S+C + C C S L C A G P PG V +
Sbjct: 5415 CPCVGPDGFPKFPGERWVSNC-QSCVCDEGSVSVQCKPLPCDAQGQPPPCNRPGFVTVTR 5473
Query: 5223 AEARNCWATRGLCV 5236
A N +CV
Sbjct: 5474 PRAENPCCPETVCV 5487
Score = 100 bits (249), Expect = 4e-20
Identities = 132/564 (23%), Positives = 207/564 (36%), Gaps = 110/564 (19%)
Query: 1920 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGSPCPASCP--SPAPLTT 1975
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 4948 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5003
Query: 1976 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 2035
P+ G D +PL +E W C+ RC
Sbjct: 5004 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5034
Query: 2036 PGGGSLVCTP-----ASCGLGEVCGLLPSGQHGCQPVSTAEC--QAWGDPHYVTLDGHRF 2088
++ P +C + + C EC WG HY T DG +
Sbjct: 5035 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSY 5094
Query: 2089 NFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT----RSVTLQIYNHSLTLS 2144
F+G C Y+L H N ++ + N + + A + R++++ + + L+
Sbjct: 5095 TFRGNCTYVLMREIHA---RFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLT 5151
Query: 2145 -----ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLR 2198
+ + D + V+ F + +L + L + V + G+S+ F+G F + R
Sbjct: 5152 VTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVF-QAR 5210
Query: 2199 VP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQ--GC------- 2240
+P + + + G CG + DD G A W V ++ GC
Sbjct: 5211 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTP 5270
Query: 2241 ------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL 2294
S P P+PC P+ C ++ + A CH LVPP +F C+
Sbjct: 5271 PTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECHNLVPPGPFFNACIS 5320
Query: 2295 DACQVQGHPGGLCPAVATYVAACQAAGAQLREWR--RPDFCPFQCPAHSHYELCGDSCPG 2352
D C +G C ++ Y C+A G +WR C CP Y+ CG P
Sbjct: 5321 DHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPA 5377
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDDRYYPLGQTFYPG--- 2408
+C S + E EGC C +L + + V C C+ D G +PG
Sbjct: 5378 TCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVGPD-----GFPKFPGERW 5431
Query: 2409 -PGCDSLCRCREGG-EVSCEPSSC 2430
C S C C EG V C+P C
Sbjct: 5432 VSNCQS-CVCDEGSVSVQCKPLPC 5454
Score = 99.4 bits (246), Expect = 9e-20
Identities = 132/564 (23%), Positives = 207/564 (36%), Gaps = 110/564 (19%)
Query: 3121 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGPPCPASCP--SPAPLTT 3176
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 4948 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5003
Query: 3177 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 3236
P+ G D +PL +E W C+ RC
Sbjct: 5004 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5034
Query: 3237 PGGGSLVCTP-----ASCGLGEVCGLLPSGQHGCQPVSTAEC--QAWGDPHYVTLDGHRF 3289
++ P +C + + C EC WG HY T DG +
Sbjct: 5035 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSY 5094
Query: 3290 DFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT----RSVTLQIYNHSLTLS 3345
F+G C Y+L H N ++ + N + + A + R++++ + + L+
Sbjct: 5095 TFRGNCTYVLMREIHA---RFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLT 5151
Query: 3346 -----ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLR 3399
+ + D + V+ F + +L + L + V + G+S+ F+G F + R
Sbjct: 5152 VTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVF-QAR 5210
Query: 3400 VP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQ--GC------- 3441
+P + + + G CG + DD G A W V ++ GC
Sbjct: 5211 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTP 5270
Query: 3442 ------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL 3495
S P P+PC P+ C ++ + A CH LVPP +F C+
Sbjct: 5271 PTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECHNLVPPGPFFNACIS 5320
Query: 3496 DACQVQGHPGGLCPAVATYVAACQAAGAQLREWR--RPDFCPFQCPAHSHYELCGDSCPG 3553
D C +G C ++ Y C+A G +WR C CP Y+ CG P
Sbjct: 5321 DHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPA 5377
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDDRYYPLGQTFYPG--- 3609
+C S + E EGC C +L + + V C C+ D G +PG
Sbjct: 5378 TCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVGPD-----GFPKFPGERW 5431
Query: 3610 -PGCDSLCRCREGG-EVSCEPSSC 3631
C S C C EG V C+P C
Sbjct: 5432 VSNCQS-CVCDEGSVSVQCKPLPC 5454
Score = 93.6 bits (231), Expect = 5e-18
Identities = 126/500 (25%), Positives = 176/500 (35%), Gaps = 84/500 (16%)
Query: 780 CVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQ-RRCTCNGAT-------- 830
C P V+S P+ + GC + L E W E C RC +
Sbjct: 4989 CPTSPPPVSSAPLSSPSPAPGCD-NAIPLRQVNETWTLENCTVARCVGDNRVVLLDPKPV 5047
Query: 831 HQVTCRDK----------QSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRF 880
VTC +K Q C C C G HY +FDG +
Sbjct: 5048 ANVTCVNKHLPIKVSDPSQPCDFHYECEC-------------ICSMWGGSHYSTFDGTSY 5094
Query: 881 DFMGTCTYLLVGSCGQNAALPAFRVLVENEH-RGSQTVSYTRAVRVEARGVK-------- 931
F G CTY+L+ +A + ++N + S T + R R + K
Sbjct: 5095 TFRGNCTYVLMREI--HARFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLTV 5152
Query: 932 VAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD---WNARVT 988
V + G +L D + F V V V G++VT++ + AR+
Sbjct: 5153 TMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLP 5212
Query: 989 AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGCGATEPG 1046
+ + E CG C N + DD R G AA+ +W + + GC A P
Sbjct: 5213 YSLFHNNTEGQCGTCTN---NQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWA--PT 5267
Query: 1047 DCPKLDSLVAQQLQSKNECGILADP------KGPFRECHSKLDPQGAVRDCVYDRCLLPG 1100
P S A + P F ECH+ + P C+ D C G
Sbjct: 5268 GTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC--RG 5325
Query: 1101 QSGPLCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSC---GD 1155
+ C +L YA C+A G WR LC L+CPP Y+ C P +C
Sbjct: 5326 RLEVPCQSLEAYAELCRARG-VCSDWRGATGGLCDLTCPPTKVYKPCGPIQPATCNSRNQ 5384
Query: 1156 LPVPGGCGSECHEGCVCDEGFAL-SGESCLPLASCGCVHQGTYHPPGQTFYPG----PGC 1210
P G EGC C E L + + + +C CV P G +PG C
Sbjct: 5385 SPQLEGMA----EGCFCPEDQILFNAHMGICVQACPCV-----GPDGFPKFPGERWVSNC 5435
Query: 1211 DSLCHCQEGGL-VSCESSSC 1229
S C C EG + V C+ C
Sbjct: 5436 QS-CVCDEGSVSVQCKPLPC 5454
Score = 93.2 bits (230), Expect = 6e-18
Identities = 127/558 (22%), Positives = 203/558 (36%), Gaps = 109/558 (19%)
Query: 4322 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV--CGPPCPASCP--SPAPLTT 4377
C+A + + G VI + + GC N H ++ CP S P S APL++
Sbjct: 4948 CRAFGQFFSP----GEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSS 5003
Query: 4378 PAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCG 4437
P+ G D +PL +E W C+ RC
Sbjct: 5004 PSPAPG---------------CDNAIPLRQV-------------NETWTLENCTV-ARCV 5034
Query: 4438 PGGGSLVCTP-----ASCGLGEVCGLLPSGQHGCQPVSTAEC--QAWGDPHYVTLDGHRF 4490
++ P +C + + C EC WG HY T DG +
Sbjct: 5035 GDNRVVLLDPKPVANVTCVNKHLPIKVSDPSQPCDFHYECECICSMWGGSHYSTFDGTSY 5094
Query: 4491 DFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYT----RSVTLQIYNHSLTLS 4546
F+G C Y+L H N ++ + N + + A + R++++ + + L+
Sbjct: 5095 TFRGNCTYVLMREIHA---RFGNLSLYLDNHYCTASATAAAARCPRALSIHYKSMDIVLT 5151
Query: 4547 -----ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLR 4600
+ + D + V+ F + +L + L + V + G+S+ F+G F + R
Sbjct: 5152 VTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVF-QAR 5210
Query: 4601 VP-AAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQ--GC------- 4642
+P + + + G CG + DD G A W V ++ GC
Sbjct: 5211 LPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTP 5270
Query: 4643 ------GECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL 4696
S P P+PC P+ C ++ + A CH LVPP +F C+
Sbjct: 5271 PTASPAAPVSSTPTPTPCPPQ--------PLCDLMLSQ--VFAECHNLVPPGPFFNACIS 5320
Query: 4697 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWR--RPDFCPLQCPAHSHYELCGDSCPV 4754
D C +G C ++ Y C+A G +WR C L CP Y+ CG P
Sbjct: 5321 DHC--RGRLEVPCQSLEAYAELCRARGV-CSDWRGATGGLCDLTCPPTKVYKPCGPIQPA 5377
Query: 4755 SCPSLSAPEGCESACREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC 4813
+C S + E EGC C +L + + V C C+ P G +PG
Sbjct: 5378 TCNSRNQSPQLEGMA-EGCFCPEDQILFNAHMGICVQACPCVG-----PDGFPKFPGERW 5431
Query: 4814 ERRCECGPGGHVTCQEGA 4831
C+ C EG+
Sbjct: 5432 VSNCQ-----SCVCDEGS 5444
Score = 39.3 bits (90), Expect = 0.11
Identities = 53/213 (24%), Positives = 72/213 (33%), Gaps = 53/213 (24%)
Query: 4602 PAAYAASLCGLCGNYNQDPA----DDLKAVGGKPAGWQVGGAQG--CGECVSKPCPSP-- 4653
P A +C QDP +D P G++ G CGECV C +P
Sbjct: 5540 PGALPCHMCTCLSGDTQDPTVQCQEDACNNTTCPQGFEYKRVAGQCCGECVQTACLTPDG 5599
Query: 4654 ----------------CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 4697
CT E+ GG A+ ++ C G + C D
Sbjct: 5600 QPVQLNETWVNSHVDNCTVYLCEAEGGVHLLTPQPASCPDVSSCRGSLRKTGCCYSCEED 5659
Query: 4698 ACQVQ------GHPG-----------GLCPAVATYVAACQAAGAQLG--EWRR--PDFCP 4736
+CQV+ H G G CP + Y A QA Q + RR + P
Sbjct: 5660 SCQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVP 5719
Query: 4737 LQCP-------AHSHYELCGDSCPVSCPSLSAP 4762
L CP ++H + CG P P+ AP
Sbjct: 5720 LHCPNGSAILHTYTHVDECG-CTPFCVPAPMAP 5751
>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
Length = 2013
Score = 412 bits (1058), Expect = e-114
Identities = 364/1368 (26%), Positives = 549/1368 (40%), Gaps = 224/1368 (16%)
Query: 461 KAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHR 520
+A A + VC G HY TFDG + G C+Y E C F+++ +
Sbjct: 70 RASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQE 127
Query: 521 GSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVE 580
+ + V ++ + LT+G V LV+ LP S+ + + QS VE
Sbjct: 128 SAAPT--LSRVLMKVDGVVIQLTKGSV---LVNGHPVLLP--FSQSGVLIQQSSSYTKVE 180
Query: 581 LVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA-DDFLTPDGALAPDAVEFASS 639
GLV+ ++ D L L L ++ ++ CGLCG++NG P + L+ + L P +EF +
Sbjct: 181 ARLGLVLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTP--MEFGNL 238
Query: 640 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699
K+DD C+D C+ G E L G L F+ C +D +LE
Sbjct: 239 QKMDDPTEQCQDPVPEPPRNCSTGFGICEE--LLHGQL------FSGCVALVDVGSYLEA 290
Query: 700 CVYDLCVVGGERL--SLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPA 757
C DLC L +C L+ Y++ C G DWR P CP CP N +Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 758 CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG---GACVPASSCGCTFQGLQLAPGQEV 814
C +C+ C CV GC C G V CVP S C C + G APG
Sbjct: 351 CADTCSNQEHSRACEDH-CVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409
Query: 815 WADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVS 874
D C CTC+G + +C++ CP GTC G H+ +
Sbjct: 410 STD--C-TNCTCSGG--RWSCQE-VPCP-------------------GTCSVLGGAHFST 444
Query: 875 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVA 933
FDG+++ G C+Y+L C + AF VL E G + + + ++V + GV+
Sbjct: 445 FDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDGVQTV 500
Query: 934 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVV-RTDFGLTVTYDW--NARVTAK 990
V + G+V ++ + LP AA+ V +FR ++ +T GL + ++ +
Sbjct: 501 VVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQ 558
Query: 991 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1050
+ CGLCGNFN ADD G A A AF N++ +T+ C
Sbjct: 559 LAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTF--KTQAACPNIRNSFEDP 616
Query: 1051 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1110
V + +++ C L D GPF CH+ + P +C++D C LC AL+
Sbjct: 617 CSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALS 676
Query: 1111 TYAAACQAAGATVHPWRS------EELCPLSCPPHSHYEACSYGC-PLSCGDLPVPGGCG 1163
+Y AC A G + WR CP S H H C C LS GD+ G
Sbjct: 677 SYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITC--SVG 734
Query: 1164 SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFY----------------- 1205
+GC+C +G L C+ ++C C H+G+ P G++ +
Sbjct: 735 FIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIG 794
Query: 1206 ------------------------PGPGCDSLCHC-----------------------QE 1218
G GC CH E
Sbjct: 795 GQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGE 854
Query: 1219 GGLVSCESSSCGPHEACQPSGGSL--GCVAVGS-------------STCQASGDPHYTTF 1263
GG ++ E C +EA +G ++ GC +TC GD HY TF
Sbjct: 855 GGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTF 914
Query: 1264 DGRRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVANFTLR 1321
DG+ + F G C Y L Q CG + F V+ ENV G + ++ I + + F L+
Sbjct: 915 DGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELK 974
Query: 1322 LEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGN 1381
L + +V ++P + Q G +V++TD GL + +D + + +
Sbjct: 975 LSHGKVEVIGTDESQEVPYTI-------RQMGIYLVVDTDIGLVLLWDKKTSIFINLSPE 1027
Query: 1382 YYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
+ ++CGLCGN++ +DF + S G+ EFGNSW+ L P+ CP +
Sbjct: 1028 FKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK--------LSPS-CP---DAL 1075
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLS 1499
P C +K ++ C +L PT ++CH V+P + C+ D C GG+
Sbjct: 1076 APKDPCTANPFRKSWAQKQCSILHGPT--FAACHAHVEPARYYEACVNDACACDSGGDCE 1133
Query: 1500 ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP---PNSHYELCADTCSLGCSALSAPP 1556
C+ + AY AC G V WRT + CP+ C P E C + C P
Sbjct: 1134 CFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
Query: 1557 QCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKG 1616
+ C D ++ + C P +C P + + D + QC
Sbjct: 1193 R------GDCLRD---VWGLEGCYP--KC----------PPEAPIFDEDKMQCVATCPTP 1231
Query: 1617 MV---CQEH--SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEA 1671
+ C H S +PG V SC+ + GV C T K + C+ Y
Sbjct: 1232 PLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTE--RGVEC----TYKAE----ACVCTYNG 1281
Query: 1672 TCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTT 1719
+ GD YH+ DG G C + A G G + + P + TT
Sbjct: 1282 QRFHPGDVIYHTTDG-----TGGC--ISARCGANGTIERRVYPCSPTT 1322
Score = 380 bits (975), Expect = e-104
Identities = 328/1200 (27%), Positives = 479/1200 (39%), Gaps = 188/1200 (15%)
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 2126
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 2127 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLS 2186
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 2187 LAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 2245
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 2246 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 2303
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 2304 -GGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
+C +A Y C AG ++WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 2363 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCRE 2419
CE C GC C G VL G T CVPV +C C+++ Y G T+ C + C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC-S 419
Query: 2420 GGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVL 2479
GG SC+ C TC G H++TFDG+++ G C YVL
Sbjct: 420 GGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVL 460
Query: 2480 AQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANF-TLRLEQRQWKVTVNGVDM 2537
+ C + F VL E G + + +T+ + T+ + + +V +N +
Sbjct: 461 TKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYT 516
Query: 2538 KLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLM-------CG 2589
+LP+ AN I R S ++ +T GL++ LV +++ + QL CG
Sbjct: 517 QLPISAANVTIFRPSTFF--IIAQTSLGLQLNLQLVPTMQL-----FMQLAPKLRGQTCG 569
Query: 2590 LCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECP 2649
LCGN+N DDF+ +G A F N+++ CP + C
Sbjct: 570 LCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQA---------ACPNIRNSF--EDPCS 618
Query: 2650 PELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAY 2709
+E + + +C L+ GP CH V P +C+FD C + LC+ + +Y
Sbjct: 619 LSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSY 678
Query: 2710 VSACQAAGGQVEPWRNETFC-PME-CPQNSHYELCADTCSLGCSALS-APLQCPDGC--A 2764
V AC A G Q+ WR+ PM CP++ Y TC C +LS + C G
Sbjct: 679 VHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPV 738
Query: 2765 EGCQCDSG-FLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH 2823
+GC C G FL + CV C CYH G+ ++V + CTC GK+
Sbjct: 739 DGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV--HDSGAICTCTHGKL------ 790
Query: 2824 SCKPGQ----VCQPSGGILSCVNKDP-----------------CHGVTCRPQETCKE--- 2859
SC GQ VC C N P C+ C P C +
Sbjct: 791 SCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLV 850
Query: 2860 QGGQGVCLPNYE--------------------------------------ATCWLWGDPH 2881
G+G C+ + ATC ++GD H
Sbjct: 851 ADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGH 910
Query: 2882 YHSFDGRKFDFQGTCNYVLATTGCPGV-STQGLTPFTVTTKNQNRGNPAVSYVRVVTVAA 2940
Y +FDG+ + F G C Y L C G STQ F V T+N G + + + +
Sbjct: 911 YLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQ--DSFRVVTENVPCGTTGTTCSKAIKIFL 968
Query: 2941 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV 3000
G + + GKV V G + V ++ Q ++ D GL + +D +
Sbjct: 969 GGFELKLSH---GKVEVIGTDESQEVP-----YTIRQMGIYLVVDTDIGLVLLWDKKTSI 1020
Query: 3001 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 3060
+ L + G VCGLCGN D ND + ++ + +G SW+ P C D
Sbjct: 1021 FINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAP 1077
Query: 3061 SCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRD 3118
P C + + C L G F CHAHV P +++ CV D C GGD +
Sbjct: 1078 KDP-CTANPFRKSWAQKQCSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCE 1133
Query: 3119 ILCKALASYVAACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGPPCPASCPSP 3171
C A+A+Y AC G+ + WR C + C PE HY+ CG PC +C +P
Sbjct: 1134 CFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
Score = 377 bits (969), Expect = e-103
Identities = 328/1190 (27%), Positives = 476/1190 (40%), Gaps = 168/1190 (14%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 3327
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 3328 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLS 3387
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 3388 LAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 3446
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 3447 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 3504
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 3505 -GGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563
+C +A Y C AG ++WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 3564 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCRE 3620
CE C GC C G VL G T CVPV +C C+++ Y G T+ C + C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTC-S 419
Query: 3621 GGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVL 3680
GG SC+ C TC G H++TFDG ++ G C YVL
Sbjct: 420 GGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYVL 460
Query: 3681 AQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANF-TLRLEQRQWKVTVNGVDM 3738
+ C + F VL E G + + +T+ + T+ + + +V +N +
Sbjct: 461 TKPCDS----SAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYT 516
Query: 3739 KLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVR--VTVPGNYYQLMCGLCGNY 3795
+LP+ AN I R S ++ +T GL++ LV ++ + + CGLCGN+
Sbjct: 517 QLPISAANVTIFRPSTF--FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNF 574
Query: 3796 NGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEK 3855
N DDF+ +G A F N+++ CP + D C +E
Sbjct: 575 NSIQADDFRTLSGVVEATAAAFFNTFK---------TQAACP--NIRNSFEDPCSLSVEN 623
Query: 3856 KYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQ 3915
+ + +C L+ GP CH V P +C+FD C + LC+ + +YV AC
Sbjct: 624 EKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACA 683
Query: 3916 AAGGHVEPWRNETFC-PM-ECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEGCQC 3970
A G + WR+ PM CP++ Y TC C +LS + C G +GC C
Sbjct: 684 AKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCIC 743
Query: 3971 DSG-FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKV----------- 4018
G FL + CV C CYH G ++V + CTC GK+
Sbjct: 744 PKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV--HDSGAICTCTHGKLSCIGGQAPAPV 801
Query: 4019 ------------------------------VVCQEHSCKPGQVCQPSG----GILSCVTK 4044
+ C C PG VC P G G C+T
Sbjct: 802 CAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVC-PDGLVADGEGGCITA 860
Query: 4045 DPC----------HGVTCRPQ-ETCKEQGGQGVCLPN-YEATCWLWGDPHYHSFDGRKFD 4092
+ C G T R TC C + ATC ++GD HY +FDG+ +
Sbjct: 861 EDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYS 920
Query: 4093 FQGTCNYVLATTGCPGV-STQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKD 4151
F G C Y L C G STQ F V T+N G + + + + G + +
Sbjct: 921 FNGDCEYTLVQNHCGGKDSTQ--DSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSH- 977
Query: 4152 EIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHG 4211
GKV V G + V ++ Q ++ D GL + +D + + L + G
Sbjct: 978 --GKVEVIGTDESQEVP-----YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKG 1030
Query: 4212 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRL 4271
VCGLCGN D ND + ++ + +G SW+ P C D P C +
Sbjct: 1031 RVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPKDP-CTANPF 1086
Query: 4272 EQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCKALASYV 4329
+ C L G F CHAHV P +++ CV D C GGD + C A+A+Y
Sbjct: 1087 RKSWAQKQCSILH---GPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYA 1143
Query: 4330 AACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGPPCPASCPSP 4372
AC G+ + WR C + C PE HY+ CG PC +C +P
Sbjct: 1144 QACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
Score = 363 bits (931), Expect = 3e-99
Identities = 325/1192 (27%), Positives = 473/1192 (39%), Gaps = 165/1192 (13%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRV-LVENEHRGSQTVSYTRA 922
C G HY +FDG F F G C Y+ CG AA F + L ++ + T+S
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCG--AAYEDFNIQLRRSQESAAPTLS---R 135
Query: 923 VRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYD 982
V ++ GV + + + G VLV+ LPF + +Q + V GL + ++
Sbjct: 136 VLMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSGVLIQ--QSSSYTKVEARLGLVLMWN 190
Query: 983 WNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGA 1042
+ + ++ + YA CGLCG+FNG P L + FGN Q+ P
Sbjct: 191 HDDSLLLELDTKYANKTCGLCGDFNGMPVVS-ELLSHNTKLTPMEFGNL-QKMDDPTEQC 248
Query: 1043 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1102
+P P + + + G L F C + +D + C D C
Sbjct: 249 QDPVPEPPRNCSTGFGICEELLHGQL------FSGCVALVDVGSYLEACRQDLCFCEDTD 302
Query: 1103 --GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPG 1160
+C LA Y+ C AG WR + CP CP + Y C C +C +
Sbjct: 303 LLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSR 362
Query: 1161 GCGSECHEGCVCDEGFALSG---ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQ 1217
C C GC C EG L C+P++ C CV+ G + PG T+ C + C C
Sbjct: 363 ACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCS 419
Query: 1218 EGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYV 1277
GG SC+ C TC G H++TFDG+++ G C YV
Sbjct: 420 -GGRWSCQEVPC-------------------PGTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 1278 LAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRVITVQVANF-TLRLEQRQWKVTVNGVD 1335
L + C + F VL E G + + +T+ + T+ + + +V +N +
Sbjct: 460 LTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIY 515
Query: 1336 MKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRV--TVPGNYYQQMCGLCGN 1392
+LP+ AN I R S ++ +T GL++ LV +++ + Q CGLCGN
Sbjct: 516 TQLPISAANVTIFRPSTFF--IIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGN 573
Query: 1393 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELE 1452
+N DDF+ +G A F N+++ CP C +E
Sbjct: 574 FNSIQADDFRTLSGVVEATAAAFFNTFKT---------QAACPNIRNSF--EDPCSLSVE 622
Query: 1453 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 1512
+ + +C L+ GP CH V P +C+FD C + LC+ + +YV AC
Sbjct: 623 NEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHAC 682
Query: 1513 QAAGGHVEPWRTETFC--PME-CPPNSHYELCADTCSLGCSALSAPP-QCQDGC--AEGC 1566
A G + WR + C PM CP + Y TC C +LS C G +GC
Sbjct: 683 AAKGVQLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGC 741
Query: 1567 QCDSG-FLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK---------- 1615
C G FL + CV C CYH G ++V + CTC GK
Sbjct: 742 ICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGESV--HDSGAICTCTHGKLSCIGGQAPA 799
Query: 1616 -------------------------------GMVCQEHSCKPGQVCQPSG----GILSCV 1640
M C C PG VC P G G C+
Sbjct: 800 PVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVC-PDGLVADGEGGCI 858
Query: 1641 TKDPCH----------GVTCRPQ-ETCKEQGGQGVCLPN-YEATCWLWGDPHYHSFDGRK 1688
T + C G T R TC C + ATC ++GD HY +FDG+
Sbjct: 859 TAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQS 918
Query: 1689 FDFQGTCNYVLATTGCPGV-STQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH 1747
+ F G C Y L C G STQ F V T+N G + + + + G + +
Sbjct: 919 YSFNGDCEYTLVQNHCGGKDSTQ--DSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS 976
Query: 1748 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 1807
GKV V G + V ++ Q ++ D GL + +D + + L +
Sbjct: 977 H---GKVEVIGTDESQEVP-----YTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEF 1028
Query: 1808 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPED 1867
G VCGLCGN D ND + ++ + +G SW+ P C D P C +
Sbjct: 1029 KGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPKDP-CTAN 1084
Query: 1868 RLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCKALAS 1925
+ C L G F CHAHV P +++ CV D C GGD + C A+A+
Sbjct: 1085 PFRKSWAQKQCSIL---HGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAA 1141
Query: 1926 YVAACQAAGVVIEDWRAQVGCEITC----PENS---HYEVCGSPCPASCPSP 1970
Y AC G+ + WR C + C PE HY+ CG PC +C +P
Sbjct: 1142 YAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNP 1192
Score = 362 bits (929), Expect = 6e-99
Identities = 330/1207 (27%), Positives = 481/1207 (39%), Gaps = 207/1207 (17%)
Query: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134
C WG HY +FDG F F G CNYV + C G + + ++Q P +S V
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH-C-GAAYEDFN--IQLRRSQESAAPTLSRV 136
Query: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 4194
+ G I + K G V VNG LP S + + + Q +S + A GL +
Sbjct: 137 ---LMKVDGVVIQLTK---GSVLVNGHPVLLPFSQSG--VLIQQSSSYTKVEARLGLVLM 188
Query: 4195 YDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPL 4254
++ + + + L + Y CGLCG+ + P ++ + T P+ G+ + DP
Sbjct: 189 WNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLT--PMEFGNLQKMD-DPT 245
Query: 4255 CWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMG 4314
++C+ P P + G G C L G F+ C A V S+ + C D+C
Sbjct: 246 --EQCQDPVPEPPRNCST---GFGICEELLHGQ--LFSGCVALVDVGSYLEACRQDLCFC 298
Query: 4315 GGDRDIL---CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371
D D+L C LA Y C AG + +DWR C CP N Y C PC +C +
Sbjct: 299 E-DTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSN 357
Query: 4372 PAPLTTPAVCEGPCVEGCQCDAGFVLS---ADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
CE CV GC C G VL CVP++ C C NG + G+ + D
Sbjct: 358 QEH---SRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSK-CACVYNGAAYAPGATYSTD- 412
Query: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVST-AECQAWGDPHYVTLDG 4487
CT +C G+ CQ V C G H+ T DG
Sbjct: 413 ----------------CTNCTCS---------GGRWSCQEVPCPGTCSVLGGAHFSTFDG 447
Query: 4488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLS 4546
++ G C Y+L+ PC + FTV G + + + +SVTL + +
Sbjct: 448 KQYTVHGDCSYVLTKPCD-----SSAFTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVV 502
Query: 4547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA-- 4604
+ ++ ++ ++ LP ++ S ++ T+ GL L ++L + A
Sbjct: 503 IKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPK 562
Query: 4605 YAASLCGLCGNYNQDPADDLKAVGG-----KPAGWQVGGAQGCGECVSKPCPSPCTPEQQ 4659
CGLCGN+N ADD + + G A + Q + PC+ +
Sbjct: 563 LRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLSVE 622
Query: 4660 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 4719
C ++ DGP CH V P Y+ C+ D C + LC A+++YV AC
Sbjct: 623 NEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHAC 682
Query: 4720 QAAGAQLGEWRRPDFCP---LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACR------ 4770
A G QLG WR C CP Y +C +C SLS EG + C
Sbjct: 683 AAKGVQLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLS--EG-DITCSVGFIPV 738
Query: 4771 EGCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGE----------------------- 4805
+GC+C G L DT CV C C H G P GE
Sbjct: 739 DGCICPKGTFLD-DTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQA 797
Query: 4806 ---------VFY------PG-------------------PECERRCEC-------GPGGH 4824
VF+ PG P+C C C G GG
Sbjct: 798 PAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGC 857
Query: 4825 VTCQEGAACGPHEE--------------CRLEDGVQACHATGC-GRCLANGGIHYITLDG 4869
+T ++ C +E C + + C C C G HY+T DG
Sbjct: 858 ITAED-CPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDG 916
Query: 4870 RVYDLHGSCSYVLAQV-CHPKPGDED-FSIVLEKNAAGDL-----QRLLVTVAGQVVSLA 4922
+ Y +G C Y L Q C K +D F +V E G + + + + G + L+
Sbjct: 917 QSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLS 976
Query: 4923 QGQ-QVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGR 4981
G+ +V E+ +P + ++ G +V+ T GL LL+D + +++ F+GR
Sbjct: 977 HGKVEVIGTDESQEVPYTIRQM-----GIYLVVDTDIGLVLLWDKKTSIFINLSPEFKGR 1031
Query: 4982 LCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEET 5041
+CGLCGNF+ +DF + S V FG +W+ S C + P+ C A
Sbjct: 1032 VCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKL---SPSCPDALAPK--DPCTANPF 1086
Query: 5042 APYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTA 5099
+ + C L P FA C A + P+ Y+ CV D CA GD C ++AAY
Sbjct: 1087 RKSWAQKQCSILHGP--TFAACHAHVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQ 1144
Query: 5100 ACQAAGVAVKPWRTDSFCPLHCPAHS-------HYS----ICTRTC---QGSCAA-LSGL 5144
AC G+ V WRT S CPL C ++ HY C RTC +G C + GL
Sbjct: 1145 ACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGL 1203
Query: 5145 TGCTTRC 5151
GC +C
Sbjct: 1204 EGCYPKC 1210
Score = 344 bits (882), Expect = 2e-93
Identities = 350/1351 (25%), Positives = 524/1351 (38%), Gaps = 247/1351 (18%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713
C G HY TFDG F F G C YV ++ CG + +Q + + +++RV+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
Query: 3714 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 3773
++V ++L + V VNG + LP + + Q S +E GL + ++
Sbjct: 138 -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
Query: 3774 YYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCL-- 3831
+ + + Y CGLCG++NG P + ++ EFGN + P C
Sbjct: 193 DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
Query: 3832 ---PPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 3888
PP C G C +E G L S C LVD L+
Sbjct: 252 VPEPPRNCSTGFGIC---------------EELLHGQL------FSGCVALVDVGSYLEA 290
Query: 3889 CIFDLCLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADT 3946
C DLC LS +C + Y C AGG + WR FCP +CP N Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 3947 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYN--GQA-CVPIQQCGCYHNGVYYEPEQTVL 4003
C+ CS C D C GC C G + + GQ CVP+ +C C +NG Y P T
Sbjct: 351 CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYS 410
Query: 4004 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGG 4063
D C CTC SGG SC + PC G
Sbjct: 411 TD-CTN-CTC---------------------SGGRWSC-QEVPCPG-------------- 432
Query: 4064 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 4123
TC + G H+ +FDG+++ G C+YVL T C + FTV +
Sbjct: 433 ----------TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAEL 475
Query: 4124 QNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASK 4182
+ G + + ++ VT++ G + G+V +N + T LP+S A+ +++ + ++
Sbjct: 476 RRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTF 533
Query: 4183 ALLV-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSI 4239
++ GLQ++ ++ + L G CGLCGN + +D +G + +
Sbjct: 534 FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATA 593
Query: 4240 PIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVP 4299
+ +++ P + C E+ E+Y +C L+ GPF CHA V
Sbjct: 594 AAFFNTFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQLTD-ADGPFGRCHAAVK 649
Query: 4300 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSH 4357
P +++ C+ D C D LC AL+SYV AC A GV + WR V + TCP++
Sbjct: 650 PGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMT 709
Query: 4358 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGT 4416
Y C +C S + V+GC C G F+ +CV +N C C+ G+
Sbjct: 710 YHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPCYHRGS 768
Query: 4417 YHEAGSEFWADG---TCSQW----------------------CRCGPGGGS--------- 4442
G G TC+ CR G +
Sbjct: 769 MIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCH 828
Query: 4443 ---LVCTPASCGLGEVC--GLLPSGQHGC------------------------------- 4466
+ C C G VC GL+ G+ GC
Sbjct: 829 TLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCD 888
Query: 4467 -------QPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSAPCHGPPLGAENFTVTV 4518
A C +GD HY+T DG + F G CEY L+ C G ++F V
Sbjct: 889 SRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVT 948
Query: 4519 ANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVA--LPFQLDSLLHAHLSG 4576
N G+ + ++++ + + L LS K++V G + +P+ + + G
Sbjct: 949 ENVPCGTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM------G 999
Query: 4577 ADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--- 4633
+VV T GL L +D + + + + + +CGLCGN++ +D G
Sbjct: 1000 IYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVL 1059
Query: 4634 -----WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPP 4687
W++ + C + ++ PCT C ++ GP A CH V P
Sbjct: 1060 EFGNSWKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACHAHVEP 1112
Query: 4688 AQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-- 4743
A+Y++ C+ DAC G C AVA Y AC G + WR P CPL C ++
Sbjct: 1113 ARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPE 1171
Query: 4744 -----HYELCGDSCPVSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGDTC-VP 4788
HY+ CG C +C + + EGC C E + D + TC P
Sbjct: 1172 GQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTP 1231
Query: 4789 VGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAAC-GPHEECRLEDGVQA 4847
C G+ Y G V C+ C C G + AC + R G
Sbjct: 1232 PLPPRCHVHGKSYRPGAVVPSDKNCQ-SCLCTERGVECTYKAEACVCTYNGQRFHPGDVI 1290
Query: 4848 CHAT----GC--GRCLANGGIHYITLDGRVY 4872
H T GC RC ANG T++ RVY
Sbjct: 1291 YHTTDGTGGCISARCGANG-----TIERRVY 1316
Score = 343 bits (881), Expect = 2e-93
Identities = 337/1295 (26%), Positives = 509/1295 (39%), Gaps = 228/1295 (17%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311
C G HY TFDG F F G C YV ++ CG + +Q + + +++RV+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
Query: 1312 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 1371
++V ++L + V VNG + LP + + Q S +E GL + ++
Sbjct: 138 -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPP 1431
+ + + Y + CGLCG++NG P + ++ EFGN + P C P
Sbjct: 193 DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
Query: 1432 TPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 1491
P PP +C EL G L S C LVD L+ C DL
Sbjct: 252 VPEPP--RNCSTGFGICEEL--------LHGQL------FSGCVALVDVGSYLEACRQDL 295
Query: 1492 CLGGGN--LSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGC 1549
C LS +C + Y C AGG + WR FCP +CP N Y C C+ C
Sbjct: 296 CFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTC 355
Query: 1550 SALSAPPQCQDGCAEGCQCDSGFLYN--GQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606
S C+D C GC C G + + GQ CVP+ +C C +NG Y P T D C
Sbjct: 356 SNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYSTD-CT 414
Query: 1607 QQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCL 1666
CTC G+ CQE C PG
Sbjct: 415 N-CTCSGGRWS-CQEVPC-PG--------------------------------------- 432
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG- 1725
TC + G H+ +FDG+++ G C+YVL T C + FTV + + G
Sbjct: 433 -----TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAELRRCGL 480
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV- 1784
+ + ++ VT++ G + G+V +N + T LP+S A+ +++ + ++ ++
Sbjct: 481 TDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQ 538
Query: 1785 ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGG 1842
GLQ++ ++ + L G CGLCGN + +D +G + + +
Sbjct: 539 TSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFN 598
Query: 1843 SWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFF 1902
+++ P + C E+ E+Y +C L G PF CHA V P +++
Sbjct: 599 TFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQLTDADG-PFGRCHAAVKPGTYY 654
Query: 1903 KGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCG 1960
C+ D C D LC AL+SYV AC A GV + WR V + TCP++ Y
Sbjct: 655 SNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHV 714
Query: 1961 SPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAG 2019
S C +C S + V+GC C G F+ +CV +N C C+ G+ G
Sbjct: 715 STCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPCYHRGSMIPNG 773
Query: 2020 SEFWADG---TCSQW----------------------CRCGPGGGS------------LV 2042
G TC+ CR G + +
Sbjct: 774 ESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCHTLDMT 833
Query: 2043 CTPASCGLGEVC--GLLPSGQHGC------------------------------------ 2064
C C G VC GL+ G+ GC
Sbjct: 834 CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWR 893
Query: 2065 --QPVSTAECQAWGDPHYVTLDGHRFNFQGTCEY-LLSAPCHGPPLGAENFTVTVANEHR 2121
A C +GD HY+T DG ++F G CEY L+ C G ++F V N
Sbjct: 894 CTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPC 953
Query: 2122 GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT--LPFQLDSLLHAHLSGADVVV 2179
G+ + ++++ + + L LS K++V G + +P+ + + G +VV
Sbjct: 954 GTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM------GIYLVV 1004
Query: 2180 TTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG-------- 2231
T GL L +D + + + + + G +CGLCGN++ +D G
Sbjct: 1005 DTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNS 1064
Query: 2232 WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPPAQYFQ 2290
W++ + C + ++ PCT C ++ GP A CH V PA+Y++
Sbjct: 1065 WKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACHAHVEPARYYE 1117
Query: 2291 GCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS------- 2341
C+ DAC G C AVA Y AC G + WR P CP C ++
Sbjct: 1118 ACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPEGQCEW 1176
Query: 2342 HYELCGDSCPGSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGDTC--VPVGQC 2390
HY+ CG C +C + + EGC C E + D + TC P+
Sbjct: 1177 HYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTPPLPPR 1236
Query: 2391 GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSC 2425
+H Y P G C S C C E G V C
Sbjct: 1237 CHVHGKSYRP-GAVVPSDKNCQS-CLCTERG-VEC 1268
Score = 338 bits (867), Expect = 9e-92
Identities = 337/1300 (25%), Positives = 506/1300 (38%), Gaps = 238/1300 (18%)
Query: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 2512
C G HY TFDG F F G C YV ++ CG + +Q + + +++RV+
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAA---YEDFNIQLRRSQESAAPTLSRVL 137
Query: 2513 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLV 2572
++V ++L + V VNG + LP + + Q S +E GL + ++
Sbjct: 138 -MKVDGVVIQLTKGS--VLVNGHPVLLP--FSQSGVLIQQSSSYTKVEARLGLVLMWNHD 192
Query: 2573 YYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCL-- 2630
+ + + Y CGLCG++NG P + ++ EFGN + P C
Sbjct: 193 DSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKL-TPMEFGNLQKMDDPTEQCQDP 251
Query: 2631 ---PPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 2687
PP C G C +E G L S C LVD L+
Sbjct: 252 VPEPPRNCSTGFGIC---------------EELLHGQL------FSGCVALVDVGSYLEA 290
Query: 2688 CIFDLCLGGGN--LSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADT 2745
C DLC LS +C + Y C AGG + WR FCP +CP N Y C
Sbjct: 291 CRQDLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSP 350
Query: 2746 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYN--GQA-CVPIQQCGCYHNGAYYEPEQTVL 2802
C+ CS C D C GC C G + + GQ CVP+ +C C +NGA Y P T
Sbjct: 351 CADTCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATYS 410
Query: 2803 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGG 2862
D C CTC SGG SC + PC G
Sbjct: 411 TD-CTN-CTC---------------------SGGRWSC-QEVPCPG-------------- 432
Query: 2863 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 2922
TC + G H+ +FDG+++ G C+YVL T C + FTV +
Sbjct: 433 ----------TCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPCDS------SAFTVLAEL 475
Query: 2923 QNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASK 2981
+ G + + ++ VT++ G + G+V +N + T LP+S A+ +++ + ++
Sbjct: 476 RRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIYTQLPISAAN--VTIFRPSTF 533
Query: 2982 ALLV-ADFGLQVSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSI 3038
++ GLQ++ ++ + L G CGLCGN + +D +G + +
Sbjct: 534 FIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATA 593
Query: 3039 PIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 3098
+ +++ P + C E+ E+Y +C L G PF CHA V
Sbjct: 594 AAFFNTFKTQAACPNIRNSFEDPCSLSVEN--EKY-AQHWCSQLTDADG-PFGRCHAAVK 649
Query: 3099 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSH 3156
P +++ C+ D C D LC AL+SYV AC A GV + WR V + TCP++
Sbjct: 650 PGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMT 709
Query: 3157 YEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGT 3215
Y C +C S + V+GC C G F+ +CV +N C C+ G+
Sbjct: 710 YHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGKCVQASN-CPCYHRGS 768
Query: 3216 YHEAGSEFWADG---TCSQW----------------------CRCGPGGGS--------- 3241
G G TC+ CR G +
Sbjct: 769 MIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPMVFFDCRNATPGDTGAGCQKSCH 828
Query: 3242 ---LVCTPASCGLGEVC--GLLPSGQHGC------------------------------- 3265
+ C C G VC GL+ G+ GC
Sbjct: 829 TLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCD 888
Query: 3266 -------QPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSAPCHGPPLGAENFTVTV 3317
A C +GD HY+T DG + F G CEY L+ C G ++F V
Sbjct: 889 SRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVT 948
Query: 3318 ANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT--LPFQLDSLLHAHLSG 3375
N G+ + ++++ + + L LS K++V G + +P+ + + G
Sbjct: 949 ENVPCGTTGTTCSKAIKIFLGGFELKLS---HGKVEVIGTDESQEVPYTIRQM------G 999
Query: 3376 ADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--- 3432
+VV T GL L +D + + + + + G +CGLCGN++ +D G
Sbjct: 1000 IYLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVL 1059
Query: 3433 -----WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGP-LAPCHGLVPP 3486
W++ + C + ++ PCT C ++ GP A CH V P
Sbjct: 1060 EFGNSWKL--SPSCPDALAP--KDPCTANPFRKSWAQKQCSIL---HGPTFAACHAHVEP 1112
Query: 3487 AQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS-- 3542
A+Y++ C+ DAC G C AVA Y AC G + WR P CP C ++
Sbjct: 1113 ARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDYYNPE 1171
Query: 3543 -----HYELCGDSCPGSCPS--------LSAPEGCESAC-REGCVCDAGFVLSGDTC--V 3586
HY+ CG C +C + + EGC C E + D + TC
Sbjct: 1172 GQCEWHYQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCVATCPTP 1231
Query: 3587 PVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSC 3626
P+ +H Y P G C S C C E G V C
Sbjct: 1232 PLPPRCHVHGKSYRP-GAVVPSDKNCQS-CLCTERG-VEC 1268
Score = 288 bits (737), Expect = 1e-76
Identities = 268/1037 (25%), Positives = 389/1037 (37%), Gaps = 197/1037 (18%)
Query: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-----SQAV 4528
C WG HY T DG F F G C Y+ S C E+F + + S+ +
Sbjct: 81 CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA---AYEDFNIQLRRSQESAAPTLSRVL 137
Query: 4529 SYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLS 4588
V +Q+ S+ V+G V LPF +L S + V GL
Sbjct: 138 MKVDGVVIQLTKGSVL----------VNGHPVLLPFSQSGVL-IQQSSSYTKVEARLGLV 186
Query: 4589 LAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPA-DDLKAVGGKPAGWQVGGAQGCGECVS 4647
L ++ D + L + YA CGLCG++N P +L + K + G Q + +
Sbjct: 187 LMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPMEFGNLQKMDD-PT 245
Query: 4648 KPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGCLLDACQVQGHP- 4705
+ C P + G C + G L + C LV Y + C D C +
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEEL--LHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDL 303
Query: 4706 -GGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 4764
+C +A Y C AG +WR PDFCP +CP + Y C C +C +
Sbjct: 304 LSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363
Query: 4765 CESACREGCVCDAGFVLS--GDT-CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 4821
CE C GC C G VL G T CVPV +C C+++G Y G + +C C C
Sbjct: 364 CEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY--STDCTN-CTCS- 419
Query: 4822 GGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYV 4881
GG +CQE C G C GG H+ T DG+ Y +HG CSYV
Sbjct: 420 GGRWSCQE-VPCP-------------------GTCSVLGGAHFSTFDGKQYTVHGDCSYV 459
Query: 4882 LAQVCHPKPGDEDFSIVLEKNAAG--DLQRLLVTVA------GQVVSLAQGQQVTVDGEA 4933
L + C F+++ E G D + L +V VV + +V ++
Sbjct: 460 LTKPCDSSA----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKASGEVFLNQIY 515
Query: 4934 VALPVAVGRVRVTAEGRNMVL-QTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLCGNFN 4990
LP++ V + ++ QT+ GL+L L M + RG+ CGLCGNFN
Sbjct: 516 TQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFN 575
Query: 4991 GNWSDDFVLPNG----SAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYES 5046
+DDF +G +AA+ TF P + C L+ E Y +
Sbjct: 576 SIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCS-------LSVENEKY-A 627
Query: 5047 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 5106
C QL + GPF C A + P Y+ C++D C + + LC +L++Y AC A GV
Sbjct: 628 QHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCLCAALSSYVHACAAKGV 687
Query: 5107 AVKPWRTDSFCP---LHCPAHSHYSICTRTCQGSCAALS-GLTGCTTRCF--EGCECDD- 5159
+ WR D C CP Y TCQ +C +LS G C+ +GC C
Sbjct: 688 QLGGWR-DGVCTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDITCSVGFIPVDGCICPKG 746
Query: 5160 RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTS--------------------------- 5192
FL G C+ +C C H G +P S+ S
Sbjct: 747 TFLDDTGKCVQASNCPCYHRGSMIPNGESVHDSGAICTCTHGKLSCIGGQAPAPVCAAPM 806
Query: 5193 ---DCSERCSCSSSSG---------LTCQAAGCPPGRVCE-----------VKAEARNC- 5228
DC + +G +TC + C PG VC + AE C
Sbjct: 807 VFFDCRNATPGDTGAGCQKSCHTLDMTCYSPQCVPGCVCPDGLVADGEGGCITAEDCPCV 866
Query: 5229 -------------------------WATR-----GLCVLSVGANLTTFDGARGATTSPGV 5258
W C + + TFDG +
Sbjct: 867 HNEASYRAGQTIRVGCNTCTCDSRMWRCTDDPCLATCAVYGDGHYLTFDGQSYSFNGDCE 926
Query: 5259 YEL-SSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGV--WVNG 5315
Y L + C G +T +RVV E C G T +K + ++ G
Sbjct: 927 YTLVQNHCGGKDSTQDSFRVVTENVPC----------------GTTGTTCSKAIKIFLGG 970
Query: 5316 LRVDLPAEKLASVSVSRTPDGSLLVRQKA---------GVQVWLGANGKVAVIVSNDHAG 5366
+ L K+ + + + +RQ G+ + + + +S + G
Sbjct: 971 FELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDIGLVLLWDKKTSIFINLSPEFKG 1030
Query: 5367 KLCGACGNFDGDQTNDW 5383
++CG CGNFD ND+
Sbjct: 1031 RVCGLCGNFDDIAVNDF 1047
Score = 185 bits (469), Expect = 1e-45
Identities = 153/557 (27%), Positives = 248/557 (44%), Gaps = 61/557 (10%)
Query: 4845 VQACHATGCGR-CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL---E 4900
V+A + GR C G HY T DG V+ G C+YV ++ C EDF+I L +
Sbjct: 69 VRASNPAHNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGA--AYEDFNIQLRRSQ 126
Query: 4901 KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGL 4960
++AA L R+L+ V G V+ L +G V V+G V LP + V + ++ GL
Sbjct: 127 ESAAPTLSRVLMKVDGVVIQLTKGS-VLVNGHPVLLPFSQSGVLIQQSSSYTKVEARLGL 185
Query: 4961 RLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGS 5020
L+++ D LL+ + + + + CGLCG+FNG +L + + + +E FG +
Sbjct: 186 VLMWNHDDSLLLELDTKYANKTCGLCGDFNGMPVVSELLSHNTKLTPME-FGNLQKMDDP 244
Query: 5021 SKGCGEGC--GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVY 5078
++ C + P+ C C +L + Q F+ C A++ Y C
Sbjct: 245 TEQCQDPVPEPPRNCSTGFG----------ICEELLHGQ-LFSGCVALVDVGSYLEACRQ 293
Query: 5079 DLCAQKGDK--AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQG 5136
DLC + + +C +LA Y+ C AG + WR FCP CP + Y C C
Sbjct: 294 DLCFCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKCPNNMQYHECRSPCAD 353
Query: 5137 SCAALSGLTGCTTRCFEGCECDDRFLL---SQGVCIPVQDCGCTHNG-RYLPVNSSLLTS 5192
+C+ C C GC C + +L Q C+PV C C +NG Y P + ++
Sbjct: 354 TCSNQEHSRACEDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAP--GATYST 411
Query: 5193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 5252
DC+ C+CS +CQ CP G C + GA+ +TFDG +
Sbjct: 412 DCT-NCTCSGGR-WSCQEVPCP------------------GTCSVLGGAHFSTFDGKQYT 451
Query: 5253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICH-GKTEAVGQVHIFFQDGMVTLTPNKG- 5310
Y L+ C + V+AE++ C +E + DG+ T+ K
Sbjct: 452 VHGDCSYVLTKPCDSSA-----FTVLAELRRCGLTDSETCLKSVTLSLDGVQTVVVIKAS 506
Query: 5311 --VWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHAG 5366
V++N + LP A+V++ R ++ + G+Q + L ++ + ++ G
Sbjct: 507 GEVFLNQIYTQLPI-SAANVTIFRPSTFFIIAQTSLGLQLNLQLVPTMQLFMQLAPKLRG 565
Query: 5367 KLCGACGNFDGDQTNDW 5383
+ CG CGNF+ Q +D+
Sbjct: 566 QTCGLCGNFNSIQADDF 582
Score = 178 bits (452), Expect = 1e-43
Identities = 167/596 (28%), Positives = 244/596 (40%), Gaps = 115/596 (19%)
Query: 3548 GDSCPGSCPSLSAPEGCESA-CREGCVCDAGFVLSGDT-CVPVGQCGCLHDDRYYPLGQT 3605
G C SC +L C S C GCVC G V G+ C+ C C+H++ Y GQT
Sbjct: 820 GAGCQKSCHTLDMT--CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT 877
Query: 3606 FYPGPG---CDS-LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPH 3661
G CDS + RC + +P C+A TC GD H
Sbjct: 878 IRVGCNTCTCDSRMWRCTD------DP-----------------CLA----TCAVYGDGH 910
Query: 3662 YTTFDGHRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVAN 3719
Y TFDG + F G C Y L Q CG + F V+ ENV G + ++ I + +
Sbjct: 911 YLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGG 970
Query: 3720 FTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVT 3779
F L+L + +V ++P + Q G +V++TD GL + +D + +
Sbjct: 971 FELKLSHGKVEVIGTDESQEVPYTIR-------QMGIYLVVDTDIGLVLLWDKKTSIFIN 1023
Query: 3780 VPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPG 3839
+ + +CGLCGN++ +DF + S G+ EFGNSW+ P+CP
Sbjct: 1024 LSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK---------LSPSCPDA 1074
Query: 3840 SAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GG 3897
A P D C +K ++ C +L PT ++CH V+P + C+ D C G
Sbjct: 1075 LA---PKDPCTANPFRKSWAQKQCSILHGPT--FAACHAHVEPARYYEACVNDACACDSG 1129
Query: 3898 GNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMEC----PQNS---HYELCADTCSLG 3950
G+ C+ + AY AC G V WR + CP+ C P+ HY+ C C
Sbjct: 1130 GDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRT 1188
Query: 3951 CSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQ 4010
C + P G C D ++ + C P +C P + + D + Q
Sbjct: 1189 C-------RNPRG---DCLRD---VWGLEGCYP--KC----------PPEAPIFDEDKMQ 1223
Query: 4011 C--TCHVGKVVV-CQEH--SCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 4065
C TC + C H S +PG V SC+ + GV C T K +
Sbjct: 1224 CVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTE--RGVEC----TYKAE---- 1273
Query: 4066 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTT 4121
C+ Y + GD YH+ DG G C + A G G + + P + TT
Sbjct: 1274 ACVCTYNGQRFHPGDVIYHTTDG-----TGGC--ISARCGANGTIERRVYPCSPTT 1322
Score = 176 bits (446), Expect = 6e-43
Identities = 165/596 (27%), Positives = 245/596 (41%), Gaps = 115/596 (19%)
Query: 2347 GDSCPGSCPSLSAPEGCESA-CREGCVCDAGFVLSGDT-CVPVGQCGCLHDDRYYPLGQT 2404
G C SC +L C S C GCVC G V G+ C+ C C+H++ Y GQT
Sbjct: 820 GAGCQKSCHTLDMT--CYSPQCVPGCVCPDGLVADGEGGCITAEDCPCVHNEASYRAGQT 877
Query: 2405 FYPGPG---CDS-LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPH 2460
G CDS + RC + +P C+A TC GD H
Sbjct: 878 IRVGCNTCTCDSRMWRCTD------DP-----------------CLA----TCAVYGDGH 910
Query: 2461 YTTFDGRRFDFMGTCVYVLAQT-CGTRPGLH-RFAVLQENVAWGNGRVSVTRVITVQVAN 2518
Y TFDG+ + F G C Y L Q CG + F V+ ENV G + ++ I + +
Sbjct: 911 YLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSKAIKIFLGG 970
Query: 2519 FTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVT 2578
F L+L + +V ++P + Q G +V++TD GL + +D + +
Sbjct: 971 FELKLSHGKVEVIGTDESQEVPYTIR-------QMGIYLVVDTDIGLVLLWDKKTSIFIN 1023
Query: 2579 VPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPG 2638
+ + +CGLCGN++ +DF + S G+ EFGNSW+ P+CP
Sbjct: 1024 LSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWK---------LSPSCP-- 1072
Query: 2639 SEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GG 2696
+ P + C +K ++ C +L PT ++CH V+P + C+ D C G
Sbjct: 1073 -DALAPKDPCTANPFRKSWAQKQCSILHGPT--FAACHAHVEPARYYEACVNDACACDSG 1129
Query: 2697 GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMEC----PQNS---HYELCADTCSLG 2749
G+ C+ + AY AC G V WR + CP+ C P+ HY+ C C
Sbjct: 1130 GDCECFCTAVAAYAQACHEVGLCVS-WRTPSICPLFCDYYNPEGQCEWHYQPCGVPCLRT 1188
Query: 2750 CSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQ 2809
C + P G C D ++ + C P +C P + + D + Q
Sbjct: 1189 C-------RNPRG---DCLRD---VWGLEGCYP--KC----------PPEAPIFDEDKMQ 1223
Query: 2810 C--TCHVGKVVV-CQEH--SCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQG 2864
C TC + C H S +PG V SC+ + GV C T K +
Sbjct: 1224 CVATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTE--RGVEC----TYKAE---- 1273
Query: 2865 VCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTT 2920
C+ Y + GD YH+ DG G C + A G G + + P + TT
Sbjct: 1274 ACVCTYNGQRFHPGDVIYHTTDG-----TGGC--ISARCGANGTIERRVYPCSPTT 1322
Score = 151 bits (381), Expect = 2e-35
Identities = 128/453 (28%), Positives = 186/453 (41%), Gaps = 82/453 (18%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDP 478
G A A G + DC S SC+ + C C V+GG
Sbjct: 400 GAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG--TCSVLGGA----------------- 440
Query: 479 HYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG---------SRRVSYVG 529
H++TFDG++Y + G CSY + + C AF+V A+ G S +S G
Sbjct: 441 HFSTFDGKQYTVHGDCSYVLTKPCDSS----AFTVLAELRRCGLTDSETCLKSVTLSLDG 496
Query: 530 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVV-------ELV 582
+ TV S G V ++ ++LP+S + + +++ ++ +L
Sbjct: 497 VQTVVVIKAS--------GEVFLNQIYTQLPISAAN--VTIFRPSTFFIIAQTSLGLQLN 546
Query: 583 FGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL 642
LV T QL + L + + Q CGLCGN+N ADDF T G + A F +++K
Sbjct: 547 LQLVPTM----QLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602
Query: 643 DDGDYLCEDGCQNNCPACTPGQ--AQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQC 700
+ ++ C + AQH+ C LT DGPF CH + P + C
Sbjct: 603 QAACPNIRNSFEDPCSLSVENEKYAQHW-----CSQLTDADGPFGRCHAAVKPGTYYSNC 657
Query: 701 VYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS------PANCPLSCPANSRYELC 754
++D C LC LS+Y AC G+ +G WR CP S + C
Sbjct: 658 MFDTCNCERSEDCLCAALSSYVHACAAKGVQLGGWRDGVCTKPMTTCPKSMTYHYHVSTC 717
Query: 755 GPACPTSCNGAAAPSNCS-GRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQLAPGQ 812
P C + G CS G V+GC+C G F+ G CV AS+C C +G + G+
Sbjct: 718 QPTCRSLSEG---DITCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRGSMIPNGE 774
Query: 813 EVWADELCQRRCTCNGATHQVTCRDKQSCPAGE 845
V CTC TH K SC G+
Sbjct: 775 SVHDSGAI---CTC---TH-----GKLSCIGGQ 796
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 401 bits (1030), Expect = e-110
Identities = 391/1473 (26%), Positives = 547/1473 (37%), Gaps = 284/1473 (19%)
Query: 1131 LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGESCL---- 1184
LCP+ PP + + C PG G+ C E EG + C
Sbjct: 73 LCPIYKPPETRPAKWNRTVRTCC-----PGWGGAHCTEALAKASPEGHCFAMWQCQLQAG 127
Query: 1185 -PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1243
AS G + + P GQ+++ G + C L SS QP G++G
Sbjct: 128 SANASAGSLEECCARPWGQSWWDGSS-QACRSCSSRHLPGSASSPA----LLQPLAGAVG 182
Query: 1244 CV----AVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLH---------- 1289
+ S+TC + HY TFDGR + F+G C Y+LA + +H
Sbjct: 183 QLWSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQP 242
Query: 1290 ----RFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANG 1345
R + E V G VSV + + ++ L QW
Sbjct: 243 GHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL----------------- 285
Query: 1346 QIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN 1405
G +V+ G+ V D + ++V + Q GLCG YNG P+DDF +P
Sbjct: 286 -------GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPG 338
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKY---QKEEFCG 1462
G A A FGNSW +S CL G C P ++E + + ++ C
Sbjct: 339 GGLAMLAATFGNSWRLPGSESGCLDAVEVAQG---CDPLGLIDADVEPGHLRAEAQDVCH 395
Query: 1463 LLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQAA 1515
L GP CH V P + C+F C G G +C+ +YV AC
Sbjct: 396 QLLE--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARR 453
Query: 1516 GGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQ--CQDGCAEGCQCDSGFL 1573
H+ WR FC CP Y C C C A+ + C++ C GC+C G
Sbjct: 454 HIHIR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLF 512
Query: 1574 YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPS 1633
+NG CVP C CY+ Y P TV Q+C P
Sbjct: 513 WNGTLCVPAAHCPCYYCRQRYVPGDTVR--------------------------QLCNP- 545
Query: 1634 GGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQG 1693
CV +D + Q +C A C + GD HY +FDGR + F G
Sbjct: 546 -----CVCRDG------------RWHCAQALC----PAECAVGGDGHYLTFDGRSYSFWG 584
Query: 1694 TCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGK 1753
GC Q + ++ A S + ++V+ T+I + + G
Sbjct: 585 G-------QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLR--DSGA 635
Query: 1754 VRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD-VTLPSSYHGAVC 1812
V VNG LP A+G +SV + +S LL+ G QV + + V +TL + V
Sbjct: 636 VLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQ 694
Query: 1813 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT--------C 1864
GLCG +N +D + P G + SI + ++ G +G CP+ C
Sbjct: 695 GLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---------KGRCPSEDSALLSPC 745
Query: 1865 PEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALA 1924
C L F CH V E F+ C+ VC D LC L+
Sbjct: 746 TTHSQRHAFAEAACAILHSSV---FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLS 802
Query: 1925 SYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCV 1984
+Y C G WR Q C + CP Y C C C P G CV
Sbjct: 803 AYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGEL----GSCV 857
Query: 1985 EGCQCDAGFVLSAD-RCVPLN---------------------NGCGCWANGTY-----HE 2017
GC C G + + +CVP + N C C G + H
Sbjct: 858 AGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHC 917
Query: 2018 AGSEF------WADGTCSQWC-------RCGPGG-GSLVCTPASCGLGEVC---GLLP-- 2058
F +A G C C C G VC P + L E C L P
Sbjct: 918 PSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCR 977
Query: 2059 -SGQ----------------------HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095
SGQ H + CQA G PHYVT DG F + G CE
Sbjct: 978 HSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACE 1037
Query: 2096 YLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDG 2155
YLL G FTV+ N G+ ++ T+++ +++ + R + V+G
Sbjct: 1038 YLLVREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGTVVHMLRGRAVTVNG 1089
Query: 2156 VFVTLP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214
V VT P L +G ++++T GL+L +DG + V +++ + G + GLCG++
Sbjct: 1090 VSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDF 1149
Query: 2215 NQDPADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQQESFGGPDACGVIS 2270
+ D ++DL++ G +P + +P P PCT + CG +
Sbjct: 1150 DGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALL 1209
Query: 2271 ATDGPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREW 2327
PL CH VPP Q+++ CL DAC G LC A+ATY C G +R W
Sbjct: 1210 Q---PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-W 1265
Query: 2328 RRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG--CE-SACREGCVCDAGFVLSGDTC 2384
R + C QC YE CG +CP +C G C+ AC EGC C G +L G C
Sbjct: 1266 RSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGAC 1325
Query: 2385 VPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG--------------------GEVS 2424
+ C C +P G G C C+EG GE
Sbjct: 1326 LEPASCPCEWGRNSFPPGSVLQKDCG---NCTCQEGQWHCGGDGGHCEELVPACAEGEAL 1382
Query: 2425 C-EPSSCGPH-------ETCRPSGGSLGCVAVG 2449
C E C PH + C GC A G
Sbjct: 1383 CQENGHCVPHGWLCDNQDDCGDGSDEEGCAAPG 1415
Score = 400 bits (1027), Expect = e-110
Identities = 388/1469 (26%), Positives = 538/1469 (36%), Gaps = 267/1469 (18%)
Query: 3531 PDFCPFQCPAHSHYELCGDSCPGSCPSLSAP---EGCESACREGCVCDAGFVLSGDTCVP 3587
P CP P + + CP E A EG C A +
Sbjct: 71 PGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGH-CFAMWQCQLQAGSA 129
Query: 3588 VGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCV 3647
G L + P GQ+++ G CR + P S +P G++G +
Sbjct: 130 NASAGSLEECCARPWGQSWWDGSS--QACRSCSSRHL---PGSASSPALLQPLAGAVGQL 184
Query: 3648 ----AVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLH------------ 3691
S TC + HY TFDG + F+G C Y+LA + +H
Sbjct: 185 WSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGH 244
Query: 3692 --RFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQI 3749
R + E V G VSV + + ++ L QW
Sbjct: 245 CQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL------------------- 285
Query: 3750 RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGS 3809
G +V+ G+ V D + ++V + GLCG YNG P+DDF +P G
Sbjct: 286 -----GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGG 340
Query: 3810 QAGNANEFGNSWEEVVPDSPCLPPPTCPPGS--AGCIPSDKCPPELEKKYQKEEFCGLLS 3867
A A FGNSW +S CL G G I +D P L + Q + C L
Sbjct: 341 LAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQ--DVCHQLL 398
Query: 3868 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQAAGGH 3920
GP CH V P + C+F C G G +C+ +YV AC H
Sbjct: 399 E--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
Query: 3921 VEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ--CPDGCAEGCQCDSGFLYNG 3978
+ WR FC CP Y C C C A+ + C + C GC+C G +NG
Sbjct: 457 IR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNG 515
Query: 3979 QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGI 4038
CVP C CY+ Y P TV Q+C P
Sbjct: 516 TLCVPAAHCPCYYCRQRYVPGDTVR--------------------------QLCNP---- 545
Query: 4039 LSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 4098
CV +D + Q +C A C + GD HY +FDGR + F G
Sbjct: 546 --CVCRDG------------RWHCAQALC----PAECAVGGDGHYLTFDGRSYSFWGG-- 585
Query: 4099 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 4158
GC Q + ++ A S + ++V+ T+I + + G V V
Sbjct: 586 -----QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLV 638
Query: 4159 NGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVD-VTLPSSYHGAVCGLC 4217
NG LP A+G +SV + +S LL+ G QV + + V +TL + V GLC
Sbjct: 639 NGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLC 697
Query: 4218 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT--------CPED 4269
G +N +D + P G + SI + ++ G +G CP+ C
Sbjct: 698 GTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---------KGRCPSEDSALLSPCTTH 748
Query: 4270 RLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYV 4329
C L S F CH V E F+ C+ VC D LC L++Y
Sbjct: 749 SQRHAFAEAACAILHSSV---FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYA 805
Query: 4330 AACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC 4389
C G WR Q C + CP Y C P C C P G CV GC
Sbjct: 806 RRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGEL----GSCVAGC 860
Query: 4390 QCDAGFVLSAD-RCVPLN---------------------NGCGCWANGTY-----HEAGS 4422
C G + + +CVP + N C C G + H
Sbjct: 861 NCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQ 920
Query: 4423 EF------WADGTCSQWC-------RCGPGG-GSLVCTPASCGLGEVC---GLLP---SG 4462
F +A G C C C G VC P + L E C L P SG
Sbjct: 921 AFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSG 980
Query: 4463 Q----------------------HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 4500
Q H + CQA G PHYVT DG F + G CEYLL
Sbjct: 981 QWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLL 1040
Query: 4501 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 4560
G FTV+ N G+ ++ T+++ +++ + R + V+GV V
Sbjct: 1041 VREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGTVVHMLRGRAVTVNGVSV 1092
Query: 4561 ALP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQD 4619
P L +G ++++T GL+L +DG + V +++ + + GLCG+++ D
Sbjct: 1093 TPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGD 1152
Query: 4620 PADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQQESFGGPDACGVISATD 4675
++DL++ G +P + +P P PCT + CG +
Sbjct: 1153 ASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQ-- 1210
Query: 4676 GPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRP 4732
PL CH VPP Q+++ CL DAC G LC A+ATY C G + WR
Sbjct: 1211 -PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHV-RWRSQ 1268
Query: 4733 DFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG--CE-SACREGCVCDAGFVLSGDTCVPV 4789
+ C LQC YE CG +CP +C G C+ AC EGC C G +L G C+
Sbjct: 1269 ELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEP 1328
Query: 4790 GQCGCLHDGRYYPLGEVFY-----------------PGPECERRCECGPGGHVTCQEGAA 4832
C C +P G V G CE G CQE
Sbjct: 1329 ASCPCEWGRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENGH 1388
Query: 4833 CGPH-------EECRLEDGVQACHATGCG 4854
C PH ++C + C A GCG
Sbjct: 1389 CVPHGWLCDNQDDCGDGSDEEGCAAPGCG 1417
Score = 392 bits (1007), Expect = e-108
Identities = 392/1488 (26%), Positives = 544/1488 (36%), Gaps = 280/1488 (18%)
Query: 2330 PDFCPFQCPAHSHYELCGDSCPGSCPSLSAP---EGCESACREGCVCDAGFVLSGDTCVP 2386
P CP P + + CP E A EG C A +
Sbjct: 71 PGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTEALAKASPEGH-CFAMWQCQLQAGSA 129
Query: 2387 VGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCV 2446
G L + P GQ+++ G CR + P S +P G++G +
Sbjct: 130 NASAGSLEECCARPWGQSWWDGSS--QACRSCSSRHL---PGSASSPALLQPLAGAVGQL 184
Query: 2447 ----AVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLH------------ 2490
S TC + HY TFDGR + F+G C Y+LA + +H
Sbjct: 185 WSQHQRPSATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGH 244
Query: 2491 --RFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQI 2548
R + E V G VSV + + ++ L QW
Sbjct: 245 CQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL------------------- 285
Query: 2549 RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGS 2608
G +V+ G+ V D + ++V + GLCG YNG P+DDF +P G
Sbjct: 286 -----GDWLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGG 340
Query: 2609 QAGNANEFGNSWEEVVPDSPCLPPPTCPPGSE--GCIPSEECPPELEKKYQKEEFCGLLS 2666
A A FGNSW +S CL G + G I ++ P L + Q + C L
Sbjct: 341 LAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQ--DVCHQLL 398
Query: 2667 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGG-------GNLSILCSNIHAYVSACQAAGGQ 2719
GP CH V P + C+F C G G +C+ +YV AC
Sbjct: 399 E--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIH 456
Query: 2720 VEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQ--CPDGCAEGCQCDSGFLYNG 2777
+ WR FC CP Y C C C A+ + C + C GC+C G +NG
Sbjct: 457 IR-WRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNG 515
Query: 2778 QACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGI 2837
CVP C CY+ Y P TV Q+C P
Sbjct: 516 TLCVPAAHCPCYYCRQRYVPGDTVR--------------------------QLCNP---- 545
Query: 2838 LSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCN 2897
CV +D + Q +C A C + GD HY +FDGR + F G
Sbjct: 546 --CVCRDG------------RWHCAQALC----PAECAVGGDGHYLTFDGRSYSFWGG-- 585
Query: 2898 YVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRV 2957
GC Q + ++ A S + ++V+ T+I + + G V V
Sbjct: 586 -----QGCRYSLVQDYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLV 638
Query: 2958 NGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD-VTLPSSYHGAVCGLC 3016
NG LP A+G +SV + +S LL+ G QV + + V +TL + V GLC
Sbjct: 639 NGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLC 697
Query: 3017 GNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT--------CPED 3068
G +N +D + P G + SI + ++ G +G CP+ C
Sbjct: 698 GTFTQNQQDDFLTPAGDVETSIAAFASKFQVAG---------KGRCPSEDSALLSPCTTH 748
Query: 3069 RLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYV 3128
C L F CH V E F+ C+ VC D LC L++Y
Sbjct: 749 SQRHAFAEAACAILHSSV---FQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYA 805
Query: 3129 AACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC 3188
C G WR Q C + CP Y C P C C P G CV GC
Sbjct: 806 RRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGKPEDCGEL----GSCVAGC 860
Query: 3189 QCDAGFVLSAD-RCVPLN---------------------NGCGCWANGTY-----HEAGS 3221
C G + + +CVP + N C C G + H
Sbjct: 861 NCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPSQ 920
Query: 3222 EF------WADGTCSQWC-------RCGPGG-GSLVCTPASCGLGEVC---GLLP---SG 3261
F +A G C C C G VC P + L E C L P SG
Sbjct: 921 AFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSG 980
Query: 3262 Q----------------------HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLL 3299
Q H + CQA G PHYVT DG F + G CEYLL
Sbjct: 981 QWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLL 1040
Query: 3300 SAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 3359
G FTV+ N G+ ++ T+++ +++ + R + V+GV V
Sbjct: 1041 VREASG------LFTVSAQNLPCGASGLTCTKALAVRL--EGTVVHMLRGRAVTVNGVSV 1092
Query: 3360 TLP-FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQD 3418
T P L +G ++++T GL+L +DG + V +++ + G + GLCG+++ D
Sbjct: 1093 TPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGD 1152
Query: 3419 PADDLKAVGG--KPAGWQVGGAQGCGECVSKP--CPSPCTPEQQESFGGPDACGVISATD 3474
++DL++ G +P + +P P PCT + CG +
Sbjct: 1153 ASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQ-- 1210
Query: 3475 GPL-APCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRP 3531
PL CH VPP Q+++ CL DAC G LC A+ATY C G +R WR
Sbjct: 1211 -PLFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-WRSQ 1268
Query: 3532 DFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG--CE-SACREGCVCDAGFVLSGDTCVPV 3588
+ C QC YE CG +CP +C G C+ AC EGC C G +L G C+
Sbjct: 1269 ELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEP 1328
Query: 3589 GQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG--------------------GEVSC-E 3627
C C +P G G C C+EG GE C E
Sbjct: 1329 ASCPCEWGRNSFPPGSVLQKDCG---NCTCQEGQWHCGGDGGHCEELVPACAEGEALCQE 1385
Query: 3628 PSSCGPH-------ETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGH 3668
C PH + C GC A G G+ T GH
Sbjct: 1386 NGHCVPHGWLCDNQDDCGDGSDEEGCAAPG------CGEGQMTCSSGH 1427
Score = 389 bits (999), Expect = e-107
Identities = 363/1317 (27%), Positives = 514/1317 (39%), Gaps = 217/1317 (16%)
Query: 469 TAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYV 528
+A C + HY TFDGR Y +G C+Y + + + + +RV+ +
Sbjct: 192 SATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRCPQPGHCQRVT-M 250
Query: 529 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 588
G V + +VS+ +G+ LV +S L LS L G V+ G+VV
Sbjct: 251 GPEEVLIQAGNVSV-KGQ----LVPEGQSWLLHGLSLQWL-----GDWLVLSGGLGVVVR 300
Query: 589 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 648
D +++S+ Q GLCG YNG P DDF+ P G LA A F +SW+L +
Sbjct: 301 LDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESG 360
Query: 649 CEDGCQ--NNCPA-------CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQ 699
C D + C PG + E +C L L+GPF CH + P + E
Sbjct: 361 CLDAVEVAQGCDPLGLIDADVEPGHLR-AEAQDVCHQL--LEGPFGQCHAQVSPAEYHEA 417
Query: 700 CVYDLCVVG-------GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYE 752
C++ C G + ++C ++Y QAC I + WR P C CP Y
Sbjct: 418 CLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYS 476
Query: 753 LCGPACPTSCN--GAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGLQLAP 810
C CP SC G +C CV GC C G +G CVPA+ C C + + P
Sbjct: 477 DCVSLCPPSCEAVGQGEEESCR-EECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYVP 535
Query: 811 GQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDP 870
G V R CN CRD + A C + C GD
Sbjct: 536 GDTV--------RQLCN----PCVCRDGRWHCAQALCPAE-------------CAVGGDG 570
Query: 871 HYVSFDGRRFDFMG--TCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEAR 928
HY++FDGR + F G C Y LV + ++L+ EH S A+ V
Sbjct: 571 HYLTFDGRSYSFWGGQGCRYSLVQDYVKG------QLLILLEHGACDAGSCLHAISVSLE 624
Query: 929 GVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVT 988
+ +R G VLV+ LP+ A+G + V R ++ G V + + V
Sbjct: 625 DTHIQLRDS--GAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVA 681
Query: 989 -AKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGD 1047
+ +A + GLCG F + DD G + AF + +Q G
Sbjct: 682 YITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQ--------VAGKGR 733
Query: 1048 CPKLDSLVAQQLQSKNE--------CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1099
CP DS + + ++ C IL F+ECH +D + C+ C
Sbjct: 734 CPSEDSALLSPCTTHSQRHAFAEAACAIL--HSSVFQECHRLVDKEPFYLRCLAAVCGCD 791
Query: 1100 GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVP 1159
S LC L+ YA C GA+ PWR++ LCP+ CP Y C+ C CG P
Sbjct: 792 PGSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---P 847
Query: 1160 GGCG--SECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
CG C GC C G E C+P + C C + PG C+ C C
Sbjct: 848 EDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM--KECNR-CIC 904
Query: 1217 QEGGLVSCESSSCGPHEACQ-----------------------PSGGSLGCVAVGSST-- 1251
QE GL +C + C C P+G + GCV +
Sbjct: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
Query: 1252 -----------CQASGD--------------------------------------PHYTT 1262
C+ SG PHY T
Sbjct: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
Query: 1263 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1322
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++ + +
Sbjct: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHM 1079
Query: 1323 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNY 1382
R VTVNGV + P V + + G +++ T GL + +D V V + +
Sbjct: 1080 -LRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
Query: 1383 YQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCI 1442
++ GLCG+++GD +D + G A +SW L P PG +
Sbjct: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--------LSPLCPEPGD---L 1187
Query: 1443 PSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSI 1500
P H C + CG L P L CH V PQ + C++D C GG+
Sbjct: 1188 P-HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
Query: 1501 LCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP--QC 1558
LCS I Y C G HV WR++ C ++C YE C TC C P C
Sbjct: 1245 LCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHC 1303
Query: 1559 Q-DGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK-- 1615
Q C EGC C G L +G AC+ C C G P +VL +C CTC G+
Sbjct: 1304 QVVACVEGCFCPEGTLLHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQEGQWH 1361
Query: 1616 ----GMVCQE--HSCKPGQ-VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVC 1665
G C+E +C G+ +CQ +G CV HG C Q+ C + + C
Sbjct: 1362 CGGDGGHCEELVPACAEGEALCQENG---HCVP----HGWLCDNQDDCGDGSDEEGC 1411
Score = 387 bits (994), Expect = e-106
Identities = 398/1449 (27%), Positives = 547/1449 (37%), Gaps = 248/1449 (17%)
Query: 1939 DWRAQVGCEITCPENSHYEVCGSPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 1991
D +++G + P + + SP P CP P T PA P G C
Sbjct: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
Query: 1992 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 2035
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
Query: 2036 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQG 2092
PG S + P + +G++ QH +P +T C +W HY T DG ++F G
Sbjct: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
Query: 2093 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 2152
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 216 RCTYLLAGAADS------TWAVHLTPGDRCPQP-GHCQRVTMG------------PEEVL 256
Query: 2153 VDGVFVTLPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 2204
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
Query: 2205 GSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGECVSKPCPSPCTPE 2255
G GLCG YN P DD GG A W++ G++ GC + V
Sbjct: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV----------- 365
Query: 2256 QQESFGGPDACGVISAT------------------DGPLAPCHGLVPPAQYFQGCLLDAC 2297
E G D G+I A +GP CH V PA+Y + CL C
Sbjct: 366 --EVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
Query: 2298 Q-------VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 2350
+G +C A+YV AC +R WR+P FC CP Y C C
Sbjct: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSDCVSLC 482
Query: 2351 PGSCPSLSA--PEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPG 2408
P SC ++ E C C GC C G +G CVP C C Y Q + PG
Sbjct: 483 PPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPG 536
Query: 2409 PGCDSLCR---CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFD 2465
LC CR+G C + C P E C GD HY TFD
Sbjct: 537 DTVRQLCNPCVCRDG-RWHCAQALC-PAE------------------CAVGGDGHYLTFD 576
Query: 2466 GRRFDFMGT--CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 2523
GR + F G C Y L Q + +L E+ A G S I+V + + ++L
Sbjct: 577 GRSYSFWGGQGCRYSLVQDYVKG----QLLILLEHGACDAG--SCLHAISVSLEDTHIQL 630
Query: 2524 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR-VTVPGN 2582
V VNG D+ LP + A G + + S ++ G +V + L V +T+
Sbjct: 631 RD-SGAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPR 688
Query: 2583 YYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGC 2642
+ + GLCG + + +DDF P G + F + ++ CP SE
Sbjct: 689 HAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGR-------CP--SEDS 739
Query: 2643 IPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 2702
C ++ E C +L S CH+LVD + C+ +C L
Sbjct: 740 ALLSPCTTHSQRHAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCDPGSDCL 797
Query: 2703 CSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD- 2761
C + AY C A G PWRN+T CP+ CP Y CA C C P C +
Sbjct: 798 CPVLSAYARRC-AQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---PEDCGEL 853
Query: 2762 -GCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGAYYEPEQTVLID--------------- 2804
C GC C G L++ + CVP C C Y P + +
Sbjct: 854 GSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCT 913
Query: 2805 --NCRQQCTCHVGKV-------VVCQE----HSCKPGQ----VCQPSGGILS--CVNKDP 2845
+C Q C V + C HSC G VC P +L CV D
Sbjct: 914 ARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDL 973
Query: 2846 C----HGVTCRPQETCKEQGGQGVCLPNY--------EATCWLWGDPHYHSFDGRKFDFQ 2893
C G P T +E VC C G PHY +FDG F +
Sbjct: 974 CPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYP 1033
Query: 2894 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 2953
G C Y+L GL FTV+ +N G ++ + + V GT + + +
Sbjct: 1034 GACEYLLVR------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRA- 1084
Query: 2954 KVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 3013
V VNGV P +S+ + LL GL + +D RV V L + G V
Sbjct: 1085 -VTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA 1143
Query: 3014 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP-TCPEDRLEQ 3072
GLCG+ D + +ND G L P+ + SWR PLC + G P C +
Sbjct: 1144 GLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP--GDLPHPCTMNTHRA 1198
Query: 3073 YEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAA 3130
CG L FT CHA VPP+ ++ C+ D C GGD + LC A+A+Y
Sbjct: 1199 GWARARCGALLQPL---FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
Query: 3131 CQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC 3190
C G + WR+Q C + C YE CGP CP +C P CVEGC C
Sbjct: 1256 CARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFC 1314
Query: 3191 DAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWAD-GTCS----QWCRCGPGGGSLVC 3244
G +L C+ C C W ++ GS D G C+ QW CG GG
Sbjct: 1315 PEGTLLHGGACLE-PASCPCEWGRNSF-PPGSVLQKDCGNCTCQEGQW-HCGGDGGHCEE 1371
Query: 3245 TPASCGLGE 3253
+C GE
Sbjct: 1372 LVPACAEGE 1380
Score = 381 bits (978), Expect = e-104
Identities = 394/1449 (27%), Positives = 544/1449 (37%), Gaps = 248/1449 (17%)
Query: 3140 DWRAQVGCEITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 3192
D +++G + P + + P P CP P T PA P G C
Sbjct: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
Query: 3193 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 3236
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
Query: 3237 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQG 3293
PG S + P + +G++ QH +P +T C +W HY T DG + F G
Sbjct: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
Query: 3294 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 3353
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 216 RCTYLLAGAADS------TWAVHLTPGDRCPQP-GHCQRVTMG------------PEEVL 256
Query: 3354 VDGVFVTLPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 3405
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
Query: 3406 GSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGECVSKPCPSPCTPE 3456
G GLCG YN P DD GG A W++ G++ GC + V
Sbjct: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAV----------- 365
Query: 3457 QQESFGGPDACGVISAT------------------DGPLAPCHGLVPPAQYFQGCLLDAC 3498
E G D G+I A +GP CH V PA+Y + CL C
Sbjct: 366 --EVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAYC 423
Query: 3499 Q-------VQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC 3551
+G +C A+YV AC +R WR+P FC CP Y C C
Sbjct: 424 AGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSDCVSLC 482
Query: 3552 PGSCPSLSA--PEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPG 3609
P SC ++ E C C GC C G +G CVP C C Y Q + PG
Sbjct: 483 PPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPG 536
Query: 3610 PGCDSLCR---CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFD 3666
LC CR+G C + C P E C GD HY TFD
Sbjct: 537 DTVRQLCNPCVCRDG-RWHCAQALC-PAE------------------CAVGGDGHYLTFD 576
Query: 3667 GHRFDFMGT--CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 3724
G + F G C Y L Q + +L E+ A G S I+V + + ++L
Sbjct: 577 GRSYSFWGGQGCRYSLVQDYVKG----QLLILLEHGACDAG--SCLHAISVSLEDTHIQL 630
Query: 3725 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR-VTVPGN 3783
V VNG D+ LP + A G + + S ++ G +V + L V +T+
Sbjct: 631 RD-SGAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPR 688
Query: 3784 YYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGC 3843
+ + GLCG + + +DDF P G + F + ++ CP +
Sbjct: 689 HAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGR-------CPSEDSAL 741
Query: 3844 IPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 3903
+ C ++ E C +L S CH+LVD + C+ +C L
Sbjct: 742 L--SPCTTHSQRHAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCDPGSDCL 797
Query: 3904 CSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD- 3962
C + AY C A G PWRN+T CP+ CP Y CA C C P C +
Sbjct: 798 CPVLSAYARRC-AQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---PEDCGEL 853
Query: 3963 -GCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLID--------------- 4005
C GC C G L++ + CVP C C Y P + +
Sbjct: 854 GSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLWNCT 913
Query: 4006 --NCRQQCTCHVGKV-------VVCQE----HSCKPGQ----VCQPSGGILS--CVTKDP 4046
+C Q C V + C HSC G VC P +L CV D
Sbjct: 914 ARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDL 973
Query: 4047 C----HGVTCRPQETCKEQGGQGVCLPNY--------EATCWLWGDPHYHSFDGRKFDFQ 4094
C G P T +E VC C G PHY +FDG F +
Sbjct: 974 CPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYP 1033
Query: 4095 GTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIG 4154
G C Y+L GL FTV+ +N G ++ + + V GT + + +
Sbjct: 1034 GACEYLLVR------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRA- 1084
Query: 4155 KVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVC 4214
V VNGV P +S+ + LL GL + +D RV V L + G V
Sbjct: 1085 -VTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVA 1143
Query: 4215 GLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP-TCPEDRLEQ 4273
GLCG+ D + +ND G L P+ + SWR PLC + G P C +
Sbjct: 1144 GLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP--GDLPHPCTMNTHRA 1198
Query: 4274 YEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAA 4331
CG L FT CHA VPP+ ++ C+ D C GGD + LC A+A+Y
Sbjct: 1199 GWARARCGALLQPL---FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADE 1255
Query: 4332 CQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC 4391
C G + WR+Q C + C YE CGP CP +C P CVEGC C
Sbjct: 1256 CARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFC 1314
Query: 4392 DAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWAD-GTCS----QWCRCGPGGGSLVC 4445
G +L C+ C C W ++ GS D G C+ QW CG GG
Sbjct: 1315 PEGTLLHGGACLE-PASCPCEWGRNSF-PPGSVLQKDCGNCTCQEGQW-HCGGDGGHCEE 1371
Query: 4446 TPASCGLGE 4454
+C GE
Sbjct: 1372 LVPACAEGE 1380
Score = 377 bits (968), Expect = e-103
Identities = 360/1274 (28%), Positives = 497/1274 (39%), Gaps = 171/1274 (13%)
Query: 863 TCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL---PAFRVLVENEHRGSQTVSY 919
TC HY +FDGR + F+G CTYLL G+ A+ P R + H T+
Sbjct: 194 TCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVHLTPGDRC-PQPGHCQRVTMG- 251
Query: 920 TRAVRVEARGVKVAVRREYPGQ--VLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGL 977
V ++A V V + GQ +L LQ+L G V+ G+
Sbjct: 252 PEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWL--------------GDWLVLSGGLGV 297
Query: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ-EET 1036
V D ++ V GLCG +NG P DD GGG A A FGNSW+ +
Sbjct: 298 VVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGS 357
Query: 1037 RPGC-GATEPGD-CPKLDSLVAQ------QLQSKNECGILADPKGPFRECHSKLDPQGAV 1088
GC A E C L + A + ++++ C L + GPF +CH+++ P
Sbjct: 358 ESGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLE--GPFGQCHAQVSPAEYH 415
Query: 1089 RDCVYDRCL-------LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH 1141
C++ C G+ +C A+Y AC + WR C CP
Sbjct: 416 EACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQL 474
Query: 1142 YEACSYGCPLSCGDLPV--PGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHP 1199
Y C CP SC + C EC GC C G +G C+P A C C + +
Sbjct: 475 YSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPCYYCRQRYV 534
Query: 1200 PGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPH 1259
PG T C+ C C++G C + C + C GD H
Sbjct: 535 PGDTVRQL--CNP-CVCRDGRW-HCAQALC-------------------PAECAVGGDGH 571
Query: 1260 YTTFDGRRFDFMGT--CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVAN 1317
Y TFDGR + F G C Y L Q + +L E+ A G S I+V + +
Sbjct: 572 YLTFDGRSYSFWGGQGCRYSLVQDYVKG----QLLILLEHGACDAG--SCLHAISVSLED 625
Query: 1318 FTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVR-V 1376
++L V VNG D+ LP + A G + + S ++ G +V + L V +
Sbjct: 626 THIQLRD-SGAVLVNGQDVGLPWIGAEG-LSVRRASSAFLLLRWPGAQVLWGLSDPVAYI 683
Query: 1377 TVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPP 1436
T+ + Q+ GLCG + + +DDF P G + F + ++ CP
Sbjct: 684 TLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGR-------CP- 735
Query: 1437 GSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 1496
SED C ++ E C +L S CH+LVD + C+ +C
Sbjct: 736 -SEDSALLSPCTTHSQRHAFAEAACAILHSSV--FQECHRLVDKEPFYLRCLAAVCGCDP 792
Query: 1497 NLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP 1556
LC + AY C A G PWR +T CP+ CP Y CA C C P
Sbjct: 793 GSDCLCPVLSAYARRC-AQEGASPPWRNQTLCPVMCPGGQEYRECAPACGQHCGK---PE 848
Query: 1557 QCQD--GCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDN----CRQQ- 1608
C + C GC C G L++ + CVP C C Y P + + C+++
Sbjct: 849 DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERG 908
Query: 1609 ---CTC-HAGKGMVCQE-------------------HSCKPGQ----VCQPSGGILS--C 1639
CT H C HSC G VC P +L C
Sbjct: 909 LWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERC 968
Query: 1640 VTKDPC----HGVTCRPQETCKEQGGQGVCLPNY--------EATCWLWGDPHYHSFDGR 1687
V D C G P T +E VC C G PHY +FDG
Sbjct: 969 VPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGL 1028
Query: 1688 KFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIH 1747
F + G C Y+L GL FTV+ +N G ++ + + V GT + +
Sbjct: 1029 AFTYPGACEYLLVR------EASGL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHML 1080
Query: 1748 KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSY 1807
+ V VNGV P +S+ + LL GL + +D RV V L +
Sbjct: 1081 RGRA--VTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
Query: 1808 HGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP-TCPE 1866
G V GLCG+ D + +ND G L P+ + SWR PLC + G P C
Sbjct: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL---SPLCPEP--GDLPHPCTM 1193
Query: 1867 DRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALA 1924
+ CG L FT CHA VPP+ ++ C+ D C GGD + LC A+A
Sbjct: 1194 NTHRAGWARARCGALLQPL---FTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIA 1250
Query: 1925 SYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCV 1984
+Y C G + WR+Q C + C YE CG CP +C P CV
Sbjct: 1251 TYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACV 1309
Query: 1985 EGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWAD-GTCS----QWCRCGPGG 2038
EGC C G +L C+ C C W ++ GS D G C+ QW CG G
Sbjct: 1310 EGCFCPEGTLLHGGACLE-PASCPCEWGRNSF-PPGSVLQKDCGNCTCQEGQW-HCGGDG 1366
Query: 2039 GSLVCTPASCGLGE 2052
G +C GE
Sbjct: 1367 GHCEELVPACAEGE 1380
Score = 351 bits (900), Expect = 1e-95
Identities = 350/1322 (26%), Positives = 491/1322 (37%), Gaps = 229/1322 (17%)
Query: 1671 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 1730
ATC W HY +FDGR + F G C Y+LA + LTP P
Sbjct: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH-LTP--------GDRCPQPG 243
Query: 1731 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 1790
+ + VT+ I + G V V G L S +S+ +L G+
Sbjct: 244 HCQRVTMGPEEVLI-----QAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298
Query: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
V D + +++ G GLCG + P +D + P G LA +G SWR PG +
Sbjct: 299 VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358
Query: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT-----GGPFTTCHAHVPPESFFKGC 1905
C D + P ++ PG A GPF CHA V P + + C
Sbjct: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
Query: 1906 VLDVCMGG-------GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV 1958
+ C G G + +C ASYV AC + I WR CE CP Y
Sbjct: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSD 477
Query: 1959 CGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 2018
C S CP SC + + C CV GC+C G + CVP + C C+
Sbjct: 478 CVSLCPPSCEAVGQGEEES-CREECVSGCECPRGLFWNGTLCVPAAH-CPCYY------- 528
Query: 2019 GSEFWADGTCSQWCRCGPGGG-SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 2077
C Q R PG +C P C G H Q + AEC GD
Sbjct: 529 ---------CRQ--RYVPGDTVRQLCNPCVCRDGR--------WHCAQALCPAECAVGGD 569
Query: 2078 PHYVTLDGHRFNFQG--TCEYLLSAPCHGPPLGAENFT---VTVANEHRGSQAVSYTRSV 2132
HY+T DG ++F G C Y L +++ + + EH A S ++
Sbjct: 570 GHYLTFDGRSYSFWGGQGCRYSL----------VQDYVKGQLLILLEHGACDAGSCLHAI 619
Query: 2133 TLQIYNHSLTLSARWPRKLQVDGVFVTLPF-QLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
++ + + + L R + V+G V LP+ + L S A +++ L
Sbjct: 620 SVSLEDTHIQL--RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
Query: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 2243
D + + +A + GLCG + Q+ DD G + +QV G G C
Sbjct: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGK---GRC 734
Query: 2244 VSKPCP--SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG 2301
S+ SPCT Q AC ++ ++ CH LV ++ CL C
Sbjct: 735 PSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEPFYLRCLAAVCGCDP 792
Query: 2302 HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE 2361
LCP ++ Y C GA WR CP CP Y C +C C PE
Sbjct: 793 GSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKPE 848
Query: 2362 GCE--SACREGCVCDAGFVLSGD-TCVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLCRC 2417
C +C GC C G + + CVP C C L RY P T C+ C C
Sbjct: 849 DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM---KECNR-CIC 904
Query: 2418 REGGEVSCEPSSCGPHETCR-----------------------PSGGSLGCVAVGSTT-- 2452
+E G +C C C P+G + GCV T
Sbjct: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
Query: 2453 -----------CQASGD--------------------------------------PHYTT 2463
C+ SG PHY T
Sbjct: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
Query: 2464 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 2523
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++ + +
Sbjct: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHM 1079
Query: 2524 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNY 2583
R VTVNGV + P V + + G +++ T GL + +D V V + +
Sbjct: 1080 -LRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
Query: 2584 YQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCI 2643
+ GLCG+++GD +D + G A +SW SP P P G +
Sbjct: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----SPLCPEP-------GDL 1187
Query: 2644 PSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSI 2701
P C + CG L P L CH V PQ + C++D C GG+
Sbjct: 1188 P-HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
Query: 2702 LCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD 2761
LCS I Y C G V WR++ C ++C YE C TC C Q P+
Sbjct: 1245 LCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE-----QHPE 1298
Query: 2762 --------GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCH 2813
C EGC C G L +G AC+ C C G P +VL +C CTC
Sbjct: 1299 PGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQ 1356
Query: 2814 VGKVVV------CQE--HSCKPGQ-VCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQG 2864
G+ C+E +C G+ +CQ +G CV HG C Q+ C + +
Sbjct: 1357 EGQWHCGGDGGHCEELVPACAEGEALCQENG---HCVP----HGWLCDNQDDCGDGSDEE 1409
Query: 2865 VC 2866
C
Sbjct: 1410 GC 1411
Score = 350 bits (899), Expect = 2e-95
Identities = 350/1322 (26%), Positives = 490/1322 (37%), Gaps = 229/1322 (17%)
Query: 2872 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 2931
ATC W HY +FDGR + F G C Y+LA + LTP P
Sbjct: 193 ATCASWSGFHYRTFDGRHYHFLGRCTYLLAGAADSTWAVH-LTP--------GDRCPQPG 243
Query: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 2991
+ + VT+ I + G V V G L S +S+ +L G+
Sbjct: 244 HCQRVTMGPEEVLI-----QAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVV 298
Query: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051
V D + +++ G GLCG + P +D + P G LA +G SWR PG +
Sbjct: 299 VRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSE 358
Query: 3052 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGT-----GGPFTTCHAHVPPESFFKGC 3106
C D + P ++ PG A GPF CHA V P + + C
Sbjct: 359 SGCLDAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEAC 418
Query: 3107 VLDVCMGG-------GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEV 3159
+ C G G + +C ASYV AC + I WR CE CP Y
Sbjct: 419 LFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCERLCPGGQLYSD 477
Query: 3160 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 3219
C CP SC + + C CV GC+C G + CVP + C C+
Sbjct: 478 CVSLCPPSCEAVGQGEEES-CREECVSGCECPRGLFWNGTLCVPAAH-CPCYY------- 528
Query: 3220 GSEFWADGTCSQWCRCGPGGG-SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGD 3278
C Q R PG +C P C G H Q + AEC GD
Sbjct: 529 ---------CRQ--RYVPGDTVRQLCNPCVCRDGR--------WHCAQALCPAECAVGGD 569
Query: 3279 PHYVTLDGHRFDFQG--TCEYLLSAPCHGPPLGAENFT---VTVANEHRGSQAVSYTRSV 3333
HY+T DG + F G C Y L +++ + + EH A S ++
Sbjct: 570 GHYLTFDGRSYSFWGGQGCRYSL----------VQDYVKGQLLILLEHGACDAGSCLHAI 619
Query: 3334 TLQIYNHSLTLSARWPRKLQVDGVFVTLPF-QLDSLLHAHLSGADVVVTTTSGLSLAFDG 3392
++ + + + L R + V+G V LP+ + L S A +++ L
Sbjct: 620 SVSLEDTHIQL--RDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLS 677
Query: 3393 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 3444
D + + +A + GLCG + Q+ DD G + +QV G G C
Sbjct: 678 DPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGK---GRC 734
Query: 3445 VSKPCP--SPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQG 3502
S+ SPCT Q AC ++ ++ CH LV ++ CL C
Sbjct: 735 PSEDSALLSPCTTHSQRHAFAEAACAILHSS--VFQECHRLVDKEPFYLRCLAAVCGCDP 792
Query: 3503 HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE 3562
LCP ++ Y C GA WR CP CP Y C +C C PE
Sbjct: 793 GSDCLCPVLSAYARRCAQEGAS-PPWRNQTLCPVMCPGGQEYRECAPACGQHC---GKPE 848
Query: 3563 GCE--SACREGCVCDAGFVLSGD-TCVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLCRC 3618
C +C GC C G + + CVP C C L RY P T C+ C C
Sbjct: 849 DCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATM---KECNR-CIC 904
Query: 3619 REGGEVSCEPSSCGPHETCR-----------------------PSGGSLGCVAVGSTT-- 3653
+E G +C C C P+G + GCV T
Sbjct: 905 QERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLL 964
Query: 3654 -----------CQASGD--------------------------------------PHYTT 3664
C+ SG PHY T
Sbjct: 965 DERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVT 1024
Query: 3665 FDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 3724
FDG F + G C Y+L + GL F V +N+ G ++ T+ + V++ + +
Sbjct: 1025 FDGLAFTYPGACEYLLVREAS---GL--FTVSAQNLPCGASGLTCTKALAVRLEGTVVHM 1079
Query: 3725 EQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNY 3784
R VTVNGV + P V + + G +++ T GL + +D V V + +
Sbjct: 1080 -LRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQF 1138
Query: 3785 YQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCI 3844
+ GLCG+++GD +D + G A +SW SP P P G +
Sbjct: 1139 RGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRL----SPLCPEP-------GDL 1187
Query: 3845 PSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNLSI 3902
P C + CG L P L CH V PQ + C++D C GG+
Sbjct: 1188 P-HPCTMNTHRAGWARARCGALLQPLFTL--CHAEVPPQQHYEWCLYDACGCDSGGDCEC 1244
Query: 3903 LCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD 3962
LCS I Y C G HV WR++ C ++C YE C TC C Q P+
Sbjct: 1245 LCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE-----QHPE 1298
Query: 3963 --------GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCH 4014
C EGC C G L +G AC+ C C G P +VL +C CTC
Sbjct: 1299 PGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPC-EWGRNSFPPGSVLQKDC-GNCTCQ 1356
Query: 4015 VGKVVV------CQE--HSCKPGQ-VCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 4065
G+ C+E +C G+ +CQ +G CV HG C Q+ C + +
Sbjct: 1357 EGQWHCGGDGGHCEELVPACAEGEALCQENG---HCVP----HGWLCDNQDDCGDGSDEE 1409
Query: 4066 VC 4067
C
Sbjct: 1410 GC 1411
Score = 300 bits (767), Expect = 3e-80
Identities = 270/901 (29%), Positives = 363/901 (40%), Gaps = 138/901 (15%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGT--CSYTMVELCSEDDTLPAF 511
C G+ C A A C GD HY TFDGR Y G C Y++V+ + L
Sbjct: 546 CVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILL 605
Query: 512 SVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVY 571
EH S + ++V + L + G VLV+ Q LP +EG L V
Sbjct: 606 ------EHGACDAGSCLHAISVSLEDTHIQLR--DSGAVLVNGQDVGLPWIGAEG-LSVR 656
Query: 572 QSGPRAVVELVFGLVVTYDWDCQLA-LSLPARFQDQVCGLCGNYNGDPADDFLTPDGALA 630
++ ++ G V + +A ++L R QV GLCG + + DDFLTP G +
Sbjct: 657 RASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVE 716
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
FAS +++ G C CT +H + C +L F CH
Sbjct: 717 TSIAAFASKFQVA-GKGRCPSEDSALLSPCTTHSQRHAFAEAACAILHS--SVFQECHRL 773
Query: 691 LDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSR 750
+D PF +C+ +C LC LSAYA+ C + G S WR+ CP+ CP
Sbjct: 774 VDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASP-PWRNQTLCPVMCPGGQE 832
Query: 751 YELCGPACPTSCNGAAAPSNCSGR-PCVEGCVCLPGFVASG-GACVPASSCGCTFQGLQL 808
Y C PAC C P +C CV GC C G + G CVP S C C +
Sbjct: 833 YRECAPACGQHCG---KPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRY 889
Query: 809 APGQEVWADE---LCQRR----CTCNGATHQVTCRDK------------------QSCPA 843
APG + +CQ R CT Q C + SCPA
Sbjct: 890 APGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAPGACLLTCDSPSANHSCPA 949
Query: 844 G---------------ERC-------------------SVQNGLLGCY----------PD 859
G ERC ++Q C
Sbjct: 950 GSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQR 1009
Query: 860 RFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSY 919
R G CQ SG PHYV+FDG F + G C YLLV A F V +N G+ ++
Sbjct: 1010 RSGRCQASGAPHYVTFDGLAFTYPGACEYLLV-----REASGLFTVSAQNLPCGASGLTC 1064
Query: 920 TRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQ-VQVFRQGRDAVVRTDFGLT 978
T+A+ V G V + R G+ + + + P + G + + R G ++ T GLT
Sbjct: 1065 TKALAVRLEGTVVHMLR---GRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLLSTHLGLT 1121
Query: 979 VTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRP 1038
+ +D RV ++ + + GLCG+F+GD ++DL R G A +SW+ P
Sbjct: 1122 LLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWR--LSP 1179
Query: 1039 GCGATEPGDCPKLDSLVAQQL-QSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097
C EPGD P ++ + ++ CG L P F CH+++ PQ C+YD C
Sbjct: 1180 LC--PEPGDLPHPCTMNTHRAGWARARCGALLQPL--FTLCHAEVPPQQHYEWCLYDACG 1235
Query: 1098 LP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGD 1155
G LC A+ATYA C G V WRS+ELC L C YEAC CP +C +
Sbjct: 1236 CDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCEGGQVYEACGPTCPPTCHE 1294
Query: 1156 L-PVPG-GCG-SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFY------- 1205
P PG C C EGC C EG L G +CL ASC C PPG
Sbjct: 1295 QHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCT 1354
Query: 1206 ----------PGPGCDSLC-HCQEGGLVSCESSSCGPH-------EACQPSGGSLGCVAV 1247
G C+ L C EG + E+ C PH + C GC A
Sbjct: 1355 CQEGQWHCGGDGGHCEELVPACAEGEALCQENGHCVPHGWLCDNQDDCGDGSDEEGCAAP 1414
Query: 1248 G 1248
G
Sbjct: 1415 G 1415
Score = 244 bits (624), Expect = 1e-63
Identities = 296/1212 (24%), Positives = 426/1212 (35%), Gaps = 225/1212 (18%)
Query: 4341 DWRAQVGCEITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEG------PCVEGCQCDA 4393
D +++G + P + + P P CP P T PA P G C
Sbjct: 46 DHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGAHCTE 105
Query: 4394 GFVLSADR--CVPLNNGCGCWANGTYHEAGS----------EFWADGTCSQWCR-CG--- 4437
++ C + C A AGS + W DG+ SQ CR C
Sbjct: 106 ALAKASPEGHCFAMWQ-CQLQAGSANASAGSLEECCARPWGQSWWDGS-SQACRSCSSRH 163
Query: 4438 -PGGGS--LVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQG 4494
PG S + P + +G++ QH +P +T C +W HY T DG + F G
Sbjct: 164 LPGSASSPALLQPLAGAVGQLWS-----QHQ-RPSAT--CASWSGFHYRTFDGRHYHFLG 215
Query: 4495 TCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQ 4554
C YLL+ + V + R Q + + VT+ P ++
Sbjct: 216 RCTYLLAGAAD------STWAVHLTPGDRCPQP-GHCQRVTM------------GPEEVL 256
Query: 4555 VDGVFVALPFQL-----DSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 4606
+ V++ QL LLH G +V++ G+ + D + + V
Sbjct: 257 IQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLDRTGSISISVDHELW 316
Query: 4607 ASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQ-GCGEC--VSKPCPSPCT 4655
GLCG YN P DD GG A W++ G++ GC + V++ C
Sbjct: 317 GQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGL 376
Query: 4656 PEQQESFG-----GPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQ-------VQG 4703
+ G D C + +GP CH V PA+Y + CL C +G
Sbjct: 377 IDADVEPGHLRAEAQDVCHQL--LEGPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEG 434
Query: 4704 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSL--SA 4761
+C A+YV AC + WR+P FC CP Y C CP SC ++
Sbjct: 435 RQQAVCATFASYVQACARRHIHI-RWRKPGFCERLCPGGQLYSDCVSLCPPSCEAVGQGE 493
Query: 4762 PEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 4821
E C C GC C G +G CVP C C Y + + PG + C
Sbjct: 494 EESCREECVSGCECPRGLFWNGTLCVPAAHCPC------YYCRQRYVPGDTVRQLC---- 543
Query: 4822 GGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHG--SC 4878
C DG C C C G HY+T DGR Y G C
Sbjct: 544 ---------------NPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGC 588
Query: 4879 SYVLAQVCHPKPGDEDFSIVLEKNA--AGD-LQRLLVTVAGQVVSLAQGQQVTVDGEAVA 4935
Y L Q I+LE A AG L + V++ + L V V+G+ V
Sbjct: 589 RYSLVQ----DYVKGQLLILLEHGACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVG 644
Query: 4936 LP-VAVGRVRVTAEGRNMVLQTTKGLRLLFD-GDAHLLMSIPSPFRGRLCGLCGNFNGNW 4993
LP + + V +L G ++L+ D +++ ++ GLCG F N
Sbjct: 645 LPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPVAYITLDPRHAHQVQGLCGTFTQNQ 704
Query: 4994 SDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQL 5053
DDF+ P G +S+ F + ++ G + E C + AC L
Sbjct: 705 QDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSAL--LSPCTTHSQRHAFAEAACAIL 762
Query: 5054 RNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRT 5113
+ F C ++ ++ +C+ +C LC L+AY C G A PWR
Sbjct: 763 HS--SVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEG-ASPPWRN 819
Query: 5114 DSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLS-QGVCIPVQ 5172
+ CP+ CP Y C C C G C GC C L +G C+P
Sbjct: 820 QTLCPVMCPGGQEYRECAPACGQHCGKPED-CGELGSCVAGCNCPLGLLWDPEGQCVPPS 878
Query: 5173 DCGCTHNG-RYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWAT 5231
C C RY P ++++ +C+ RC C C A CP C R
Sbjct: 879 LCPCQLGARRYAPGSATM--KECN-RCICQERGLWNCTARHCPSQAFC-----PRELVYA 930
Query: 5232 RGLCVL---SVGANLTTFDGAR-GATTSPGVYELSSRC--PGL---QNTIPWYRVVAEVQ 5282
G C+L S AN + G+ G PG L RC P L +++ WY A +Q
Sbjct: 931 PGACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLDERCVPPDLCPCRHSGQWYLPNATIQ 990
Query: 5283 ------ICH------------GKTEAVGQVHIFFQDGMVTLTP----------------- 5307
+C G+ +A G H DG+ P
Sbjct: 991 EDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTV 1050
Query: 5308 -------------------------------NKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336
+ V VNG+ V P R
Sbjct: 1051 SAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGL 1110
Query: 5337 SLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQ------EKP 5390
LL+ G+ + +V V +S G++ G CG+FDGD +ND Q +
Sbjct: 1111 FLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVLEPTAEL 1170
Query: 5391 AMEKWRAQDFSP 5402
A WR P
Sbjct: 1171 AAHSWRLSPLCP 1182
Score = 196 bits (497), Expect = 7e-49
Identities = 164/561 (29%), Positives = 228/561 (40%), Gaps = 55/561 (9%)
Query: 4654 CTPEQQESFGGPDACGVI-SATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAV 4712
C P + G P+ CG + S G P L P L CQ+ P
Sbjct: 836 CAPACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARR--YAPGS 893
Query: 4713 ATYVAACQAAGAQLGEWR-RPDFCPLQ--CPAHSHYELCGDSCPVSCPSLSAPEGCESAC 4769
AT + + G W CP Q CP Y +C ++C S SA C +
Sbjct: 894 ATMKECNRCICQERGLWNCTARHCPSQAFCPRELVY--APGACLLTCDSPSANHSCPAGS 951
Query: 4770 REGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 4829
+GCVC G VL + CVP C C H G++Y P + C C
Sbjct: 952 TDGCVCPPGTVLLDERCVPPDLCPCRHSGQWY------LPNATIQEDCN-------VC-- 996
Query: 4830 GAACGPHEECRLEDGVQACHATG---CGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVC 4886
CR + H TG GRC A+G HY+T DG + G+C Y+L +
Sbjct: 997 --------VCR----GRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLLVREA 1044
Query: 4887 HPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALP-VAVG-RVR 4944
++ + + L V + G VV + +G+ VTV+G +V P V G +
Sbjct: 1045 SGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLS 1104
Query: 4945 VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSA 5004
+ G ++L T GL LL+DG +L+ + FRGR+ GLCG+F+G+ S+D G
Sbjct: 1105 LRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQGVL 1164
Query: 5005 ASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQ 5064
+ E +WR S C E G P + A + + CG L P F C
Sbjct: 1165 EPTAELAAHSWRL---SPLCPEP-GDLPHPCTMNTHRAGW-ARARCGALLQPL--FTLCH 1217
Query: 5065 AVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCP 5122
A + P +++ C+YD C GD LC ++A Y C G V+ WR+ C L C
Sbjct: 1218 AEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVR-WRSQELCSLQCE 1276
Query: 5123 AHSHYSICTRTCQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTHN 5179
Y C TC +C G C EGC C + LL G C+ C C
Sbjct: 1277 GGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWG 1336
Query: 5180 GRYLPVNSSLLTSDCSERCSC 5200
P S+L DC C+C
Sbjct: 1337 RNSFP-PGSVLQKDCG-NCTC 1355
Score = 85.1 bits (209), Expect = 2e-15
Identities = 92/319 (28%), Positives = 114/319 (35%), Gaps = 49/319 (15%)
Query: 2580 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 2639
PG+ QL C C G+ Q G + W E P PCLPP P S
Sbjct: 4494 PGDRLQLGCKECECRRGELHCTSQGCQGLLPLS------EWSEWSPCGPCLPPSALAPAS 4547
Query: 2640 EGCIP----------SEECPPELEKKYQKEEFC----------GLLSSPTGPLSSCHKLV 2679
+ S P L + + C G T PLS
Sbjct: 4548 RTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCP 4607
Query: 2680 DPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQAAGGQVEPWRNETFCPMECP-- 2734
DP C + L + CS + + GG EPW E+ CP
Sbjct: 4608 DPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPEC 4667
Query: 2735 --QNSHYEL-CADTCSLGCSALSAPLQCPDG-CAEGCQCDSGFLYNGQACVPIQQCGCYH 2790
Q++ + L CA+ C C+ L +QC G C GC+C G L CVPI C C
Sbjct: 4668 EAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGL 4727
Query: 2791 NGA----YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPC 2846
A P Q V +D C Q CTC V + +VC C V P SC PC
Sbjct: 4728 PSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQEC---PVLGPWSAWSSC--SAPC 4779
Query: 2847 HGVTCRPQETCKEQGGQGV 2865
G T TC +GG GV
Sbjct: 4780 GGGTMERHRTC--EGGPGV 4796
Score = 84.3 bits (207), Expect = 3e-15
Identities = 92/319 (28%), Positives = 116/319 (36%), Gaps = 49/319 (15%)
Query: 3781 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 3840
PG+ QL C C G+ Q G + W E P PCLPP P S
Sbjct: 4494 PGDRLQLGCKECECRRGELHCTSQGCQGLLPLS------EWSEWSPCGPCLPPSALAPAS 4547
Query: 3841 AGCI-------PSDKCP---PELEKKYQKEEFC----------GLLSSPTGPLSSCHKLV 3880
+ P+ P P L + + C G T PLS
Sbjct: 4548 RTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCP 4607
Query: 3881 DPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQAAGGHVEPWRNETFCPMECP-- 3935
DP C + L + CS + + GG EPW E+ CP
Sbjct: 4608 DPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPEC 4667
Query: 3936 --QNSHYEL-CADTCSLGCSALSAPLQCPDG-CAEGCQCDSGFLYNGQACVPIQQCGC-- 3989
Q++ + L CA+ C C+ L +QC G C GC+C G L CVPI C C
Sbjct: 4668 EAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGL 4727
Query: 3990 --YHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPC 4047
+ P Q V +D C Q CTC V + +VC C V P SC PC
Sbjct: 4728 PSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQEC---PVLGPWSAWSSC--SAPC 4779
Query: 4048 HGVTCRPQETCKEQGGQGV 4066
G T TC +GG GV
Sbjct: 4780 GGGTMERHRTC--EGGPGV 4796
Score = 83.2 bits (204), Expect = 6e-15
Identities = 79/281 (28%), Positives = 98/281 (34%), Gaps = 43/281 (15%)
Query: 1417 NSWEEVVPDSPCLPPTPCPPGSEDCIPSH----------KCPPELEKKYQKEEFC----- 1461
+ W E P PCLPP+ P S + H P L + + C
Sbjct: 4526 SEWSEWSPCGPCLPPSALAPASRTALEEHWLRDPTGLSPTLAPLLASEQHRHRLCLDPAT 4585
Query: 1462 -----GLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSN---IHAYVSACQ 1513
G T PLS DP C + L + CS + +
Sbjct: 4586 GRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSLWGPWSPCQVPCSGGFRLRWREAEAL 4645
Query: 1514 AAGGHVEPWRTETFCPMECPPNSHYEL-----CADTCSLGCSALSAPPQCQDG-CAEGCQ 1567
GG EPW E+ CP + CA+ C C+ L QC G C GC+
Sbjct: 4646 CGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCR 4705
Query: 1568 CDSGFLYNGQACVPIQQCGC----YHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHS 1623
C G L CVPI C C + P Q V +D C Q CTC + +VC
Sbjct: 4706 CPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLD-C-QNCTC-VNESLVCPHQE 4762
Query: 1624 CKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGV 1664
C V P SC PC G T TC +GG GV
Sbjct: 4763 C---PVLGPWSAWSSC--SAPCGGGTMERHRTC--EGGPGV 4796
Score = 79.3 bits (194), Expect = 9e-14
Identities = 99/366 (27%), Positives = 131/366 (35%), Gaps = 100/366 (27%)
Query: 1419 WEEV-VPDSPCLPPTPCPPGS--ED--CIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
W+ V PC P CPPG +D C+P C CGL S+ ++
Sbjct: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
Query: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGHVEPWRT 1524
+L Q DC C+ N S++C + V S+C A GG +E RT
Sbjct: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
Query: 1525 -------------ETF---------CPMECPPNSHYELCADTCSLGCSALSAPPQC-QDG 1561
+T CP ECPP CA +C C L C Q+
Sbjct: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
Query: 1562 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE------------PEQTVLIDNCRQQC 1609
C GC C G L + CVP C C + + + P TVL NC +C
Sbjct: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
Query: 1610 TCHAGKGMVCQEHSCK--PGQVCQ--PSGGILSC----------VTKDPC-----HGVTC 1650
CH G C C+ PG+ Q G + C T+ C G C
Sbjct: 4908 VCHGG-AFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVC 4966
Query: 1651 RPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQ 1710
+P + G C+P CW G PH ++Q C L +G P V TQ
Sbjct: 4967 QPGHF---RSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEACESCLCLSGRP-VCTQ 5017
Query: 1711 GLTPFT 1716
+P T
Sbjct: 5018 HCSPLT 5023
Score = 75.1 bits (183), Expect = 2e-12
Identities = 129/543 (23%), Positives = 175/543 (32%), Gaps = 127/543 (23%)
Query: 737 SPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSG-RPCVEGCVCLPGFVASGGACVP 795
+P C CPA C CP C+ C + C +GC C G + G CVP
Sbjct: 4054 NPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVP 4113
Query: 796 ASSCGCT-FQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 854
C CT QG APG + HQ C + CS Q G L
Sbjct: 4114 IGHCDCTDAQGHSWAPGSQ-----------------HQDACNN---------CSCQAGQL 4147
Query: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGS 914
C T Q P + ++ + C++ SCG FR S
Sbjct: 4148 SC------TAQPCPPPTHCAWS--HWSAWSPCSH----SCGPRGQQSRFR--------SS 4187
Query: 915 QTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTD 974
+ S+ R E + + P L + L G+ Q + V+ D
Sbjct: 4188 TSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICED 4247
Query: 975 FGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG---QAANALAFGNS 1031
V W + SS+++ CG G+ A R ++ L
Sbjct: 4248 TECAVPEAWT------LWSSWSDCPVS-CGG--GNQVRTRACRAAAPHHRSPPCLGPDTQ 4298
Query: 1032 WQEETRPG----------------CG---ATEPGDCPKLDSLVAQQLQSKNECGILADPK 1072
+++ PG CG A+ G CP L+A+ + N + D +
Sbjct: 4299 TRQQPCPGLLEACSWGPWGPCSRSCGPGLASRSGSCP---CLMAKADPTCNSTFLHLDTQ 4355
Query: 1073 GPFRECHSKLDPQGAVRDCVYD------RC---LLPGQ----SGPLCDALATYAAACQAA 1119
G C+S P+ +CV+ RC +L Q GP A A C
Sbjct: 4356 G----CYSGPCPE----ECVWSSWSSWTRCSCRVLVQQRYRHQGPASRG-ARAGAPCTRL 4406
Query: 1120 GATVHPWRSEELCPLSCPPHSHYEACSYGCP------LS---CGDLPVPGGCGSECHEGC 1170
P SC P + AC C LS C DLP C GC
Sbjct: 4407 DGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLP-------PCQPGC 4459
Query: 1171 VCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES 1226
C +G C+P C C H G T PG GC C C+ G L C S
Sbjct: 4460 YCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAPGDRLQLGCKE-CECRRGEL-HCTS 4516
Query: 1227 SSC 1229
C
Sbjct: 4517 QGC 4519
Score = 74.7 bits (182), Expect = 2e-12
Identities = 40/122 (32%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 1133 PLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCV 1192
P CP + C+ G P SC +L P G CH GC C G L C+P C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 1193 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG----------PHEACQPSGGSL 1242
H+G +PPG T C++ C C G + +C S C P C S G
Sbjct: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
Query: 1243 GC 1244
C
Sbjct: 3203 RC 3204
Score = 73.2 bits (178), Expect = 7e-12
Identities = 94/363 (25%), Positives = 123/363 (33%), Gaps = 94/363 (25%)
Query: 2620 WEEV-VPDSPCLPPPTCPPGS---EG-CIPSEECPPELEKKYQKEEFCGLLSSPTGPLSS 2674
W+ V PC P CPPG +G C+P C CGL S+ ++
Sbjct: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
Query: 2675 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGQVEPWR- 2724
+L Q DC C+ N S++C + V S+C A GG +E R
Sbjct: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
Query: 2725 ---------------------NETFCPMECPQNSHYELCADTCSLGCSALSAPLQC-PDG 2762
N CP ECP CA +C C L C +
Sbjct: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
Query: 2763 CAEGCQCDSGFLYNGQACVPIQQCGCYHNG------------AYYEPEQTVLIDNCRQQC 2810
C GC C G L + CVP C C + A P TVL NC +C
Sbjct: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
Query: 2811 TCHVGKVVVCQEHSCK--PGQVCQP-SGGILSCVNKDPCHGVTCRPQETCKE-------- 2859
CH G C C+ PG+ Q + G L + + Q C
Sbjct: 4908 VCH-GGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVC 4966
Query: 2860 -----QGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
+ G C+P CW G PH ++Q C L +G P V TQ +
Sbjct: 4967 QPGHFRSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEACESCLCLSGRP-VCTQHCS 5020
Query: 2915 PFT 2917
P T
Sbjct: 5021 PLT 5023
Score = 73.2 bits (178), Expect = 7e-12
Identities = 95/366 (25%), Positives = 125/366 (34%), Gaps = 100/366 (27%)
Query: 3821 WEEV-VPDSPCLPPPTCPPGS----AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSS 3875
W+ V PC P CPPG C+P C CGL S+ ++
Sbjct: 4690 WDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCR------------CGLPSA-----NA 4732
Query: 3876 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV-------SACQA--AGGHVEPWR- 3925
+L Q DC C+ N S++C + V S+C A GG +E R
Sbjct: 4733 SWELAPAQAVQLDCQNCTCV---NESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRT 4789
Query: 3926 ---------------------NETFCPMECPQNSHYELCADTCSLGCSALSAPLQC-PDG 3963
N CP ECP CA +C C L C +
Sbjct: 4790 CEGGPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEP 4848
Query: 3964 CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE------------PEQTVLIDNCRQQC 4011
C GC C G L + CVP C C + + + P TVL NC +C
Sbjct: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNC-TRC 4907
Query: 4012 TCHVGKVVVCQEHSCK--PGQVCQ--PSGGILSC----------VTKDPC-----HGVTC 4052
CH G C C+ PG+ Q G + C T+ C G C
Sbjct: 4908 VCH-GGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVC 4966
Query: 4053 RPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQ 4112
+P + G C+P CW G PH ++Q C L +G P V TQ
Sbjct: 4967 QPGHF---RSQAGPCVPEDHCECWHLGRPHLPG-----SEWQEACESCLCLSGRP-VCTQ 5017
Query: 4113 GLTPFT 4118
+P T
Sbjct: 5018 HCSPLT 5023
Score = 70.5 bits (171), Expect = 4e-11
Identities = 69/277 (24%), Positives = 91/277 (32%), Gaps = 91/277 (32%)
Query: 3830 CLPPPTCPPG----SAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 3885
C P TCPPG +A C+P +CP +L + S L SC+ G
Sbjct: 2922 CAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYA-------SGAMARLDSCNNCTCVSGK 2974
Query: 3886 L----KDC----------IFDLCLGGGNLSI---------------------------LC 3904
+ + C ++ LC N+ I C
Sbjct: 2975 MACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFC 3034
Query: 3905 SNIHAYVSACQAAGGHVEPW-----------RNETF--------------------CPME 3933
S + C GG PW RN T P
Sbjct: 3035 S-----LRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGM 3089
Query: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 3993
CP++ + CA + C+ LSAP C GC C SG L CVP Q C C H G
Sbjct: 3090 CPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
Query: 3994 VYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 4030
Y P TV + C + C+C G + C C G+
Sbjct: 3149 HLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
Score = 70.1 bits (170), Expect = 6e-11
Identities = 68/277 (24%), Positives = 91/277 (32%), Gaps = 91/277 (32%)
Query: 2629 CLPPPTCPPG----SEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 2684
C P TCPPG + C+P +CP +L + S L SC+ G
Sbjct: 2922 CAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYA-------SGAMARLDSCNNCTCVSGK 2974
Query: 2685 L----KDC----------IFDLCLGGGNLSI---------------------------LC 2703
+ + C ++ LC N+ I C
Sbjct: 2975 MACTSERCPVACGWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFC 3034
Query: 2704 SNIHAYVSACQAAGGQVEPW-----------RNETF--------------------CPME 2732
S + C GG+ PW RN T P
Sbjct: 3035 S-----LRPCPGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGM 3089
Query: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNG 2792
CP++ + CA + C+ LSAP C GC C SG L CVP Q C C H G
Sbjct: 3090 CPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEG 3148
Query: 2793 AYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQ 2829
Y P TV + C + C+C G + C C G+
Sbjct: 3149 HLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
Score = 69.7 bits (169), Expect = 7e-11
Identities = 41/123 (33%), Positives = 48/123 (39%), Gaps = 13/123 (10%)
Query: 4736 PLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 4795
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 4796 HDGRYYPLGEVFYPGPECERRCECGPG-----GHVTCQEG----AACGPHEECRLEDGVQ 4846
H+G YP G CE C C G C EG + P +C G
Sbjct: 3146 HEGHLYPPGSTVV--RPCE-NCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSASCGPA 3202
Query: 4847 ACH 4849
CH
Sbjct: 3203 RCH 3205
Score = 68.6 bits (166), Expect = 2e-10
Identities = 66/243 (27%), Positives = 86/243 (35%), Gaps = 41/243 (16%)
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCP-------PELEKKYQKE 1458
G AGN SW P PC C G + + +++ P P + YQ+
Sbjct: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
Query: 1459 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 1510
FC L + P P S C + C GG +L S CS+ +
Sbjct: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
Query: 1511 ACQAAGG-HVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG--CAEGCQ 1567
AG H C CP CA+ C CS L CQD C +GC+
Sbjct: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
Query: 1568 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPG 1627
C G L CVPI C C + + D C C+C AG+ + C C P
Sbjct: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
Query: 1628 QVC 1630
C
Sbjct: 4158 THC 4160
Score = 68.2 bits (165), Expect = 2e-10
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 2334 PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 2393
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 2394 HDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHE 2434
H+ YP G T C++ C C G +C C E
Sbjct: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGE 3183
Score = 68.2 bits (165), Expect = 2e-10
Identities = 35/101 (34%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 3535 PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCL 3594
P CP + C P SC LSAP G C GC C +G +L + CVP C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 3595 HDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHE 3635
H+ YP G T C++ C C G +C C E
Sbjct: 3146 HEGHLYPPGSTVV--RPCEN-CSCVSGLIANCSSWPCAEGE 3183
Score = 67.0 bits (162), Expect = 5e-10
Identities = 35/99 (35%), Positives = 42/99 (42%), Gaps = 3/99 (3%)
Query: 5118 PLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCT 5177
P CP + C + SCA LS G C GC C LL VC+P QDC C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 5178 HNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
H G P S+++ E CSC S C + C G
Sbjct: 3146 HEGHLYPPGSTVVRP--CENCSCVSGLIANCSSWPCAEG 3182
Score = 66.2 bits (160), Expect = 8e-10
Identities = 64/243 (26%), Positives = 86/243 (35%), Gaps = 41/243 (16%)
Query: 2607 GSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECP-------PELEKKYQKE 2659
G AGN SW P PC +C G + + + P P + YQ+
Sbjct: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
Query: 2660 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 2711
FC L + P P S C + C GG +L S CS+ +
Sbjct: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
Query: 2712 ACQAAGGQVEPWR-NETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQ 2768
AG + + N C CP CA+ C CS L + C D C +GC+
Sbjct: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
Query: 2769 CDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPG 2828
C G L CVPI C C + + D C C+C G+ + C C P
Sbjct: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
Query: 2829 QVC 2831
C
Sbjct: 4158 THC 4160
Score = 65.9 bits (159), Expect = 1e-09
Identities = 65/243 (26%), Positives = 85/243 (34%), Gaps = 41/243 (16%)
Query: 3808 GSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCP-------PELEKKYQKE 3860
G AGN SW P PC +C G + + + P P + YQ+
Sbjct: 3941 GCGAGNC-----SWTSWAPWEPC--SRSCGVGQQRRLRAYRPPGPGGHWCPNILTAYQER 3993
Query: 3861 EFCGLLSSPT-------GPLSSCHKLVDPQGPLKDCIFDLCLGGGNL-SILCSNIHAYVS 3912
FC L + P P S C + C GG +L S CS+ +
Sbjct: 3994 RFCNLRACPVPGGWSRWSPWSWCDRS--------------CGGGQSLRSRSCSSPPSKNG 4039
Query: 3913 ACQAAGG-HVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDG--CAEGCQ 3969
AG H N C CP CA+ C CS L + C D C +GC+
Sbjct: 4040 GAPCAGERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCR 4099
Query: 3970 CDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPG 4029
C G L CVPI C C + + D C C+C G+ + C C P
Sbjct: 4100 CPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDAC-NNCSCQAGQ-LSCTAQPCPPP 4157
Query: 4030 QVC 4032
C
Sbjct: 4158 THC 4160
Score = 65.1 bits (157), Expect = 2e-09
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
Query: 1529 PMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCY 1588
P CP + + CA + C+ LSAP C GC C SG L CVP Q C C
Sbjct: 3087 PGMCPRDKQWLDCAQGPA-SCAELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQDCPCA 3145
Query: 1589 HNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQ 1628
H G Y P TV + C + C+C +G C C G+
Sbjct: 3146 HEGHLYPPGSTV-VRPC-ENCSCVSGLIANCSSWPCAEGE 3183
Score = 63.9 bits (154), Expect = 4e-09
Identities = 64/211 (30%), Positives = 76/211 (36%), Gaps = 54/211 (25%)
Query: 4244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
G+W W+ W C SC + R P P +G G P P
Sbjct: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP----PPKNG-GAPCPGASQERAP--- 2603
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEVC 4361
C L C GG D C+ YV+A CQ V
Sbjct: 2604 ---CGLQPCSGGTD----CELGRVYVSADLCQKGLV------------------------ 2632
Query: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
PPCP SC P + C G CVEGC+C G +L RC+PL+ C C G
Sbjct: 2633 -PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWPG 2687
Query: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGL 4452
F G CSQ C C G L+C P C L
Sbjct: 2688 VSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
Score = 63.5 bits (153), Expect = 5e-09
Identities = 65/212 (30%), Positives = 77/212 (36%), Gaps = 56/212 (26%)
Query: 3043 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 3102
G+W W+ W C SC + R P P GG A P S
Sbjct: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP------PPKNGG------APCPGASQ 2599
Query: 3103 FKG-CVLDVCMGGGDRDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEV 3159
+ C L C GG D C+ YV+A CQ V
Sbjct: 2600 ERAPCGLQPCSGGTD----CELGRVYVSADLCQKGLV----------------------- 2632
Query: 3160 CGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 3219
PPCP SC P + C G CVEGC+C G +L RC+PL+ C C
Sbjct: 2633 --PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWP 2686
Query: 3220 GSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 3251
G F G CSQ C C G L+C P C L
Sbjct: 2687 GVSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
Score = 62.8 bits (151), Expect = 9e-09
Identities = 66/227 (29%), Positives = 84/227 (37%), Gaps = 40/227 (17%)
Query: 1846 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLAPGTGGPFTTCHAHVPP 1898
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
Query: 1899 ESFFKGCVLDVCMGG-GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 1956
C GG R C +LA C D Q C CPEN +
Sbjct: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
Query: 1957 --EVC---GSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 2011
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
Query: 2012 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 2058
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
Score = 62.0 bits (149), Expect = 2e-08
Identities = 66/227 (29%), Positives = 84/227 (37%), Gaps = 40/227 (17%)
Query: 3047 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLAPGTGGPFTTCHAHVPP 3099
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
Query: 3100 ESFFKGCVLDVCMGG-GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 3157
C GG R C +LA C D Q C CPEN +
Sbjct: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
Query: 3158 --EVC---GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 3212
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
Query: 3213 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 3259
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
Score = 62.0 bits (149), Expect = 2e-08
Identities = 66/227 (29%), Positives = 84/227 (37%), Gaps = 40/227 (17%)
Query: 4248 APGWDPLCWDECRGSCPT-----CPEDRLEQYE-GPGFCG-PLSSGTGGPFTTCHAHVPP 4300
APG P W CP+ CP D ++ P C P G P++TC A
Sbjct: 2790 APGGGP-GWRSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPSIWGLWAPWSTCSAP--- 2845
Query: 4301 ESFFKGCVLDVCMGG-GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHY- 4358
C GG R C +LA C D Q C CPEN +
Sbjct: 2846 -----------CDGGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFR 2893
Query: 4359 --EVC---GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWA 4413
E C G PCP C + P C G C GC C G L C+P + C C
Sbjct: 2894 SAEQCHQEGGPCPRLCLTQGP---GIECTGFCAPGCTCPPGLFLHNASCLP-RSQCPCQL 2949
Query: 4414 NGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLP 4460
+G + +G+ D +C+ C C G + CT C + CG P
Sbjct: 2950 HGQLYASGAMARLD-SCNN-CTC--VSGKMACTSERCPV--ACGWSP 2990
Score = 61.2 bits (147), Expect = 3e-08
Identities = 45/123 (36%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 754 CGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGL----QLA 809
C CP SC C PC GC C PG + G CVP SSC C +LA
Sbjct: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELA 4737
Query: 810 PGQEVWADELCQRRCTCNGATHQVTCRDKQSCP------AGERCSVQNGLLGCYPDRFGT 863
P Q V D CQ CTC + C Q CP A CS G G +R T
Sbjct: 4738 PAQAVQLD--CQ-NCTC--VNESLVC-PHQECPVLGPWSAWSSCSAPCG--GGTMERHRT 4789
Query: 864 CQG 866
C+G
Sbjct: 4790 CEG 4792
Score = 60.5 bits (145), Expect = 4e-08
Identities = 64/212 (30%), Positives = 76/212 (35%), Gaps = 56/212 (26%)
Query: 1842 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 1901
G+W W+ W C SC + R P P GG A P S
Sbjct: 2556 GAWAM--WE--AWGPCSVSCGGGHQSRQRSCVDP------PPKNGG------APCPGASQ 2599
Query: 1902 FKG-CVLDVCMGGGDRDILCKALASYVAA--CQAAGVVIEDWRAQVGCEITCPENSHYEV 1958
+ C L C GG D C+ YV+A CQ V
Sbjct: 2600 ERAPCGLQPCSGGTD----CELGRVYVSADLCQKGLV----------------------- 2632
Query: 1959 CGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEA 2018
PCP SC P + C G CVEGC+C G +L RC+PL+ C C
Sbjct: 2633 --PPCPPSCLDPKANRS---CSGHCVEGCRCPPGLLLHDTRCLPLSE-CPCLVGEELKWP 2686
Query: 2019 GSEFWADGTCSQWCRCGPGGGSLVCTPASCGL 2050
G F G CSQ C C G L+C P C L
Sbjct: 2687 GVSFLL-GNCSQ-CVCEK--GELLCQPGGCPL 2714
Score = 60.1 bits (144), Expect = 6e-08
Identities = 35/129 (27%), Positives = 51/129 (39%), Gaps = 9/129 (6%)
Query: 2703 CSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHY---ELC---ADTCSLGCSALSAP 2756
CS++ + C Q + C +CP+N + E C C C
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 2757 LQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGK 2816
++C CA GC C G + +C+P QC C +G Y +D+C CTC GK
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC-NNCTCVSGK 2974
Query: 2817 VVVCQEHSC 2825
+ C C
Sbjct: 2975 -MACTSERC 2982
Score = 59.3 bits (142), Expect = 1e-07
Identities = 44/141 (31%), Positives = 51/141 (36%), Gaps = 30/141 (21%)
Query: 1120 GATVHPWRSEELCPLSCPPHSHYEACSYG----------------CPLSCGDLPVPGGCG 1163
G P S+E P P S C G CP SC D C
Sbjct: 2590 GGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCS 2649
Query: 1164 SECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVS 1223
C EGC C G L CLPL+ C C+ PG +F G C S C C++G L+
Sbjct: 2650 GHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG-NC-SQCVCEKGELL- 2706
Query: 1224 CESSSCGPHEACQPSGGSLGC 1244
CQP G L C
Sbjct: 2707 -----------CQPGGCPLPC 2716
Score = 59.3 bits (142), Expect = 1e-07
Identities = 36/129 (27%), Positives = 50/129 (38%), Gaps = 9/129 (6%)
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHY---ELC---ADTCSLGCSALSAP 1555
CS++ + C T+ C +CP N + E C C C
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 1556 PQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK 1615
+C CA GC C G + +C+P QC C +G Y +D+C CTC +GK
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC-NNCTCVSGK 2974
Query: 1616 GMVCQEHSC 1624
M C C
Sbjct: 2975 -MACTSERC 2982
Score = 59.3 bits (142), Expect = 1e-07
Identities = 71/248 (28%), Positives = 92/248 (37%), Gaps = 45/248 (18%)
Query: 2230 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 2286
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
Query: 2287 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC 2346
G + +G PG VA CQA + R+ CP +CP C
Sbjct: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
Query: 2347 GDSCPGSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPL---- 2401
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
Query: 2402 ---GQTFYPGPGCDSLC-RC-REGGEVSCEPSSC--GPHETCRP-SGGSLG-----CVAV 2448
Q PG C RC GG SC C P ET + + G LG C+ +
Sbjct: 4888 EEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEM 4947
Query: 2449 GSTTCQAS 2456
+T Q++
Sbjct: 4948 NATKTQSN 4955
Score = 59.3 bits (142), Expect = 1e-07
Identities = 71/248 (28%), Positives = 92/248 (37%), Gaps = 45/248 (18%)
Query: 3431 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 3487
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
Query: 3488 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC 3547
G + +G PG VA CQA + R+ CP +CP C
Sbjct: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
Query: 3548 GDSCPGSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPL---- 3602
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
Query: 3603 ---GQTFYPGPGCDSLC-RC-REGGEVSCEPSSC--GPHETCRP-SGGSLG-----CVAV 3649
Q PG C RC GG SC C P ET + + G LG C+ +
Sbjct: 4888 EEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEM 4947
Query: 3650 GSTTCQAS 3657
+T Q++
Sbjct: 4948 NATKTQSN 4955
Score = 58.5 bits (140), Expect = 2e-07
Identities = 52/198 (26%), Positives = 71/198 (35%), Gaps = 26/198 (13%)
Query: 3836 CP-PGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLC 3894
CP PG + C P D +EE C S P P+ S L P C
Sbjct: 2804 CPSPGDSSC-PGDAT---------QEEPC---SPPVCPVPSIWGL---WAPWSTCSAPCD 2847
Query: 3895 LGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHY---ELC---ADTCS 3948
G CS++ + C + C +CP+N + E C C
Sbjct: 2848 GGIQTRGRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCP 2906
Query: 3949 LGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCR 4008
C ++C CA GC C G + +C+P QC C +G Y +D+C
Sbjct: 2907 RLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSC- 2965
Query: 4009 QQCTCHVGKVVVCQEHSC 4026
CTC GK + C C
Sbjct: 2966 NNCTCVSGK-MACTSERC 2982
Score = 58.5 bits (140), Expect = 2e-07
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 13/110 (11%)
Query: 2333 CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 2390
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 2391 GCLHDDRYYPLGQTFYPG----PGCDSLCRCREGGEVSCEPSSCGPHETC 2436
C G ++ PG C++ C C + G++SC C P C
Sbjct: 4118 DCTDAQ-----GHSWAPGSQHQDACNN-CSC-QAGQLSCTAQPCPPPTHC 4160
Score = 58.5 bits (140), Expect = 2e-07
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 13/110 (11%)
Query: 3534 CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 3591
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 3592 GCLHDDRYYPLGQTFYPG----PGCDSLCRCREGGEVSCEPSSCGPHETC 3637
C G ++ PG C++ C C + G++SC C P C
Sbjct: 4118 DCTDAQ-----GHSWAPGSQHQDACNN-CSC-QAGQLSCTAQPCPPPTHC 4160
Score = 58.2 bits (139), Expect = 2e-07
Identities = 73/259 (28%), Positives = 89/259 (34%), Gaps = 63/259 (24%)
Query: 1021 QAANALAFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPK-----GP 1074
Q+ +A + +SW E PG T P D C + ++ Q Q +C DP GP
Sbjct: 3600 QSRSAGSRFSSW-ESLEPGEVVTGPCDNCTCVAGIL--QCQEVPDC---PDPGVWSSWGP 3653
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL 1134
+ +C +R RC P GP + C+ AG
Sbjct: 3654 WEDCSVSCGGGEQLRS---RRCARPPCPGPARQSRTCSTQVCREAG-------------- 3696
Query: 1135 SCPPHSHYEACS--YGCPLSCGDLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGC 1191
CP Y C GCP SC + GC SE C EGC C EG +C + C C
Sbjct: 3697 -CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQECPC 3753
Query: 1192 VHQ--------GTYHPPGQTFYPGPGCDS---------LCHCQEGGLVSCESSSC----- 1229
V T PGQ PG DS C C G L SC C
Sbjct: 3754 VLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKL-SCSLDDCFEADG 3812
Query: 1230 -----GPHEACQPSGGSLG 1243
P C S G LG
Sbjct: 3813 GFGPWSPWGPCSRSCGGLG 3831
Score = 57.8 bits (138), Expect = 3e-07
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 2350 CPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGP 2409
CP SC A C C EGC C G +L C+P+ +C CL + G +F G
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG- 2693
Query: 2410 GCDSLCRCREGGEVSCEPSSC 2430
C S C C E GE+ C+P C
Sbjct: 2694 NC-SQCVC-EKGELLCQPGGC 2712
Score = 57.8 bits (138), Expect = 3e-07
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 3551 CPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGP 3610
CP SC A C C EGC C G +L C+P+ +C CL + G +F G
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG- 2693
Query: 3611 GCDSLCRCREGGEVSCEPSSC 3631
C S C C E GE+ C+P C
Sbjct: 2694 NC-SQCVC-EKGELLCQPGGC 2712
Score = 57.4 bits (137), Expect = 4e-07
Identities = 70/262 (26%), Positives = 93/262 (35%), Gaps = 43/262 (16%)
Query: 1810 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 1866
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
Query: 1867 DRLEQYEGPGFCGPLAPGTGGPFTT---CHAHVPPE-------SFFKGCVLDVCMGGGD- 1915
RL Y PG G P + C+ P S + C D GGG
Sbjct: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWC--DRSCGGGQS 4025
Query: 1916 -RDILCKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGSPCPASCPSP 1970
R C + S AG E +A+ + CE CP C + CP C
Sbjct: 4026 LRSRSCSSPPSKNGGAPCAG---ERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC--- 4079
Query: 1971 APLTTPAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTC 2028
+ L VC+ C +GC+C G + CVP+ + C C +A WA G+
Sbjct: 4080 SDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQ 4132
Query: 2029 SQWC--RCGPGGGSLVCTPASC 2048
Q C G L CT C
Sbjct: 4133 HQDACNNCSCQAGQLSCTAQPC 4154
Score = 57.0 bits (136), Expect = 5e-07
Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 1487 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCS 1546
C C GG + C YVSA G V P CPP+
Sbjct: 2604 CGLQPCSGGTD----CELGRVYVSADLCQKGLVPP----------CPPS----------- 2638
Query: 1547 LGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCR 1606
C A C C EGC+C G L + C+P+ +C C P + L+ NC
Sbjct: 2639 --CLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGNC- 2695
Query: 1607 QQCTCHAGKGMVCQEHSC 1624
QC C G+ ++CQ C
Sbjct: 2696 SQCVCEKGE-LLCQPGGC 2712
Score = 56.2 bits (134), Expect = 8e-07
Identities = 63/242 (26%), Positives = 80/242 (33%), Gaps = 46/242 (19%)
Query: 3041 WGGSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP- 3098
W + P W P W +C SC R ++ P T P P
Sbjct: 3177 WPCAEGEPTWSPWTPWSQCSASCGPA---RCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
Query: 3099 ---PESFFKGCVLDVC------------------MGGG--DRDILC-----KALASYVAA 3130
PE+ + C+L C GGG R C + L Y
Sbjct: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
Query: 3131 CQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC 3190
+A G V + V T E + Y CGPPCP SC C C GC C
Sbjct: 3294 PRAQGEVCQALPCPV-TNCTAIEGAEYSPCGPPCPRSCDDLVH------CVWRCQPGCYC 3346
Query: 3191 DAGFVLSADRCVPLNNG-CGC--WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA 3247
G VLS++ + + G C C G H G+ C+ C C G L CT
Sbjct: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CTCLE--GRLNCTDL 3403
Query: 3248 SC 3249
C
Sbjct: 3404 PC 3405
Score = 56.2 bits (134), Expect = 8e-07
Identities = 70/262 (26%), Positives = 92/262 (35%), Gaps = 43/262 (16%)
Query: 3011 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 3067
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
Query: 3068 DRLEQYEGPGFCGPLAPGTGGPFTT---CHAHVPPE-------SFFKGCVLDVCMGGGD- 3116
RL Y PG G P + C+ P S + C D GGG
Sbjct: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWC--DRSCGGGQS 4025
Query: 3117 -RDILCKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGPPCPASCPSP 3171
R C + S AG E +A+ + CE CP C CP C
Sbjct: 4026 LRSRSCSSPPSKNGGAPCAG---ERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC--- 4079
Query: 3172 APLTTPAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTC 3229
+ L VC+ C +GC+C G + CVP+ + C C +A WA G+
Sbjct: 4080 SDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQ 4132
Query: 3230 SQWC--RCGPGGGSLVCTPASC 3249
Q C G L CT C
Sbjct: 4133 HQDACNNCSCQAGQLSCTAQPC 4154
Score = 56.2 bits (134), Expect = 8e-07
Identities = 34/107 (31%), Positives = 43/107 (40%), Gaps = 7/107 (6%)
Query: 1132 CPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSE--CHEGCVCDEGFALSGESCLPLASC 1189
C CP C+ CP C DL C + C +GC C +G C+P+ C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 1190 GCVH-QGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEAC 1235
C QG PG C++ C CQ G L SC + C P C
Sbjct: 4118 DCTDAQGHSWAPGSQHQ--DACNN-CSCQAGQL-SCTAQPCPPPTHC 4160
Score = 56.2 bits (134), Expect = 8e-07
Identities = 31/121 (25%), Positives = 47/121 (38%), Gaps = 10/121 (8%)
Query: 1512 CQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQD--GCAEGCQCD 1569
C GH P C P + C C+ C+ + CQD C GC C
Sbjct: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
Query: 1570 SGFLYNGQACVPIQQCGCYHN-----GVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC 1624
G L C+P ++C C+H G+ P + + C+ +C C G+ + C C
Sbjct: 4463 KGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL-GCK-ECECRRGE-LHCTSQGC 4519
Query: 1625 K 1625
+
Sbjct: 4520 Q 4520
Score = 55.5 bits (132), Expect = 1e-06
Identities = 69/260 (26%), Positives = 92/260 (35%), Gaps = 39/260 (15%)
Query: 4212 AVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG---GSWRAPGWDPLCWDECRGSCPTCPE 4268
A C + + P N P+ T P P G G+ W P W+ C SC +
Sbjct: 3913 ANCTMGDPLQERPCN---LPSCTELPVCPGPGCGAGNCSWTSWAP--WEPCSRSCGVGQQ 3967
Query: 4269 DRLEQYEGPGFCGP-----LSSGTGGPFTTCHAHVPPESFFKGCVLDVC---MGGGD--R 4318
RL Y PG G L++ F A P + + C GGG R
Sbjct: 3968 RRLRAYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLR 4027
Query: 4319 DILCKALASYVAACQAAGVVIEDWRAQ----VGCEITCPENSHYEVCGPPCPASCPSPAP 4374
C + S AG E +A+ + CE CP C CP C +
Sbjct: 4028 SRSCSSPPSKNGGAPCAG---ERHQARLCNPMPCEAGCPAGMEVVTCANRCPRRC---SD 4081
Query: 4375 LTTPAVCEGP--CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 4432
L VC+ C +GC+C G + CVP+ + C C +A WA G+ Q
Sbjct: 4082 LQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGH-CDC------TDAQGHSWAPGSQHQ 4134
Query: 4433 WC--RCGPGGGSLVCTPASC 4450
C G L CT C
Sbjct: 4135 DACNNCSCQAGQLSCTAQPC 4154
Score = 55.1 bits (131), Expect = 2e-06
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 7/90 (7%)
Query: 2746 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDN 2805
C C A C C EGC+C G L + C+P+ +C C P + L+ N
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 2806 CRQQCTCHVGKVVVCQEHSCKPGQVCQPSG 2835
C QC C G+++ C+PG P G
Sbjct: 2695 C-SQCVCEKGELL------CQPGGCPLPCG 2717
Score = 55.1 bits (131), Expect = 2e-06
Identities = 56/211 (26%), Positives = 68/211 (32%), Gaps = 57/211 (27%)
Query: 4244 GSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPES 4302
G RA GW P W C SC R + P PP+
Sbjct: 3248 GCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQP---------------------PPQG 3286
Query: 4303 FFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCG 4362
D C G + +C+AL V C A E + Y CG
Sbjct: 3287 LG-----DYCEGPRAQGEVCQALPCPVTNCTAI------------------EGAEYSPCG 3323
Query: 4363 PPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNG-CGC--WANGTYHE 4419
PPCP SC C C GC C G VLS++ + + G C C G H
Sbjct: 3324 PPCPRSCDDLVH------CVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHH 3377
Query: 4420 AGSEFWADGTCSQWCRCGPGGGSLVCTPASC 4450
G+ C+ C C G L CT C
Sbjct: 3378 PGARLARPDGCNH-CTCLE--GRLNCTDLPC 3405
Score = 54.7 bits (130), Expect = 2e-06
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 7/90 (7%)
Query: 3947 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDN 4006
C C A C C EGC+C G L + C+P+ +C C P + L+ N
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 4007 CRQQCTCHVGKVVVCQEHSCKPGQVCQPSG 4036
C QC C G+++ C+PG P G
Sbjct: 2695 C-SQCVCEKGELL------CQPGGCPLPCG 2717
Score = 54.7 bits (130), Expect = 2e-06
Identities = 68/233 (29%), Positives = 81/233 (34%), Gaps = 57/233 (24%)
Query: 4645 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 4683
C S PC SP TP Q S GP C + +T PL P
Sbjct: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
Query: 4684 LVPPAQYFQGCLLDACQVQGHPGGLCP----------AVATYVAACQAAGAQ-LGEW--- 4729
P + CLL C G G P + + AC Q LG++
Sbjct: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
Query: 4730 --RRPDFCP-LQCPAHS-------HYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGF 4779
+ + C L CP + Y CG CP SC L C C+ GC C G
Sbjct: 3294 PRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYCPPGQ 3350
Query: 4780 VLS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG 4830
VLS G CV G C CL G+ +PG R C H TC EG
Sbjct: 3351 VLSSNGAICVQPGHCSCLD----LLTGQRHHPGARLARPDGC---NHCTCLEG 3396
Score = 54.7 bits (130), Expect = 2e-06
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 17/128 (13%)
Query: 741 CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCG 800
CP CP C +CP C + C PC GC C G + G CVP ++C
Sbjct: 4815 CP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACP 4873
Query: 801 CTFQGL-------------QLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERC 847
CT L +L PG + + C RC C+G + D Q P
Sbjct: 4874 CTQHSLPWGLTLTLEEQAQELPPGTVLTRN--C-TRCVCHGGAFSCSLVDCQVPPGETWQ 4930
Query: 848 SVQNGLLG 855
V G LG
Sbjct: 4931 QVAPGELG 4938
Score = 54.3 bits (129), Expect = 3e-06
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 9/126 (7%)
Query: 5117 CPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDC 5174
C CPA C C C+ L C C +GC C L G C+P+ C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 5175 GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGL 5234
CT + S C+ CSC + L+C A CPP C A + W+
Sbjct: 4118 DCTDAQGHSWAPGSQHQDACN-NCSCQAGQ-LSCTAQPCPPPTHC-----AWSHWSAWSP 4170
Query: 5235 CVLSVG 5240
C S G
Sbjct: 4171 CSHSCG 4176
Score = 53.9 bits (128), Expect = 4e-06
Identities = 61/243 (25%), Positives = 80/243 (32%), Gaps = 33/243 (13%)
Query: 4626 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 4685
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
Query: 4686 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHY 4745
P Q +G C ++A C +Q + C QCP + +
Sbjct: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
Query: 4746 ---ELC---GDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGR 4799
E C G CP C + C C GC C G L +C+P QC C G+
Sbjct: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
Query: 4800 YYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLAN 4859
Y G + R C + TC G E C + G C N
Sbjct: 2953 LYASGAM-------ARLDSC---NNCTCVSGKMACTSERCPVACGWSPWTLWSLCSCSCN 3002
Query: 4860 GGI 4862
GI
Sbjct: 3003 VGI 3005
Score = 53.9 bits (128), Expect = 4e-06
Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 9/100 (9%)
Query: 2337 CPAHSHYELCGDSCPGSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLH 2394
C + CG C G C + + + C+ C+ GC C G + C+P +C C H
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
Query: 2395 DDRYYPLGQTFYPGP----GCDSLCRCREGGEVSCEPSSC 2430
G T PG GC C CR GE+ C C
Sbjct: 4483 TSA-AGAGMTLAPGDRLQLGCKE-CECRR-GELHCTSQGC 4519
Score = 53.9 bits (128), Expect = 4e-06
Identities = 30/100 (30%), Positives = 40/100 (40%), Gaps = 9/100 (9%)
Query: 3538 CPAHSHYELCGDSCPGSCPSLSAPEGCESA--CREGCVCDAGFVLSGDTCVPVGQCGCLH 3595
C + CG C G C + + + C+ C+ GC C G + C+P +C C H
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
Query: 3596 DDRYYPLGQTFYPGP----GCDSLCRCREGGEVSCEPSSC 3631
G T PG GC C CR GE+ C C
Sbjct: 4483 TSA-AGAGMTLAPGDRLQLGCKE-CECRR-GELHCTSQGC 4519
Score = 53.5 bits (127), Expect = 5e-06
Identities = 55/213 (25%), Positives = 76/213 (35%), Gaps = 26/213 (12%)
Query: 2224 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 2283
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
Query: 2284 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHY 2343
P Q +G C ++A C +Q R+ C QCP + +
Sbjct: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
Query: 2344 ---ELC---GDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDR 2397
E C G CP C + C C GC C G L +C+P QC C +
Sbjct: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
Query: 2398 YYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 2430
Y G C++ C C G+++C C
Sbjct: 2953 LYASG-AMARLDSCNN-CTC-VSGKMACTSERC 2982
Score = 53.5 bits (127), Expect = 5e-06
Identities = 55/213 (25%), Positives = 76/213 (35%), Gaps = 26/213 (12%)
Query: 3425 AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLV 3484
A GG P GW+ ++ C CP T E+ S P C P+ GL
Sbjct: 2790 APGGGP-GWR-SRSRLCPSPGDSSCPGDATQEEPCS---PPVC--------PVPSIWGLW 2836
Query: 3485 PPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHY 3544
P Q +G C ++A C +Q R+ C QCP + +
Sbjct: 2837 APWSTCSAPCDGGIQTRGRS---CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLF 2892
Query: 3545 ---ELC---GDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDR 3598
E C G CP C + C C GC C G L +C+P QC C +
Sbjct: 2893 RSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ 2952
Query: 3599 YYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 3631
Y G C++ C C G+++C C
Sbjct: 2953 LYASG-AMARLDSCNN-CTC-VSGKMACTSERC 2982
Score = 53.5 bits (127), Expect = 5e-06
Identities = 68/242 (28%), Positives = 83/242 (34%), Gaps = 64/242 (26%)
Query: 2243 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 2281
C S PC SP TP Q S GP C + +T PL P
Sbjct: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
Query: 2282 LVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP----------D 2331
P + CLL C G G P + ++ G LR R D
Sbjct: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGP----WSHCSRSCGGGLRSRTRACDQPPPQGLGD 3289
Query: 2332 FCP-----------FQCPAHS-------HYELCGDSCPGSCPSLSAPEGCESACREGCVC 2373
+C CP + Y CG CP SC L C C+ GC C
Sbjct: 3290 YCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYC 3346
Query: 2374 DAGFVLS--GDTCVPVGQCGCLH---DDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPS 2428
G VLS G CV G C CL R++P + P GC+ C C E G ++C
Sbjct: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARP-DGCNH-CTCLE-GRLNCTDL 3403
Query: 2429 SC 2430
C
Sbjct: 3404 PC 3405
Score = 53.5 bits (127), Expect = 5e-06
Identities = 68/242 (28%), Positives = 83/242 (34%), Gaps = 64/242 (26%)
Query: 3444 CVSKPCP------SPCTPEQQESFG-GPDAC----------GVISATDGPL----APCHG 3482
C S PC SP TP Q S GP C + +T PL P
Sbjct: 3174 CSSWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
Query: 3483 LVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP----------D 3532
P + CLL C G G P + ++ G LR R D
Sbjct: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGP----WSHCSRSCGGGLRSRTRACDQPPPQGLGD 3289
Query: 3533 FCP-----------FQCPAHS-------HYELCGDSCPGSCPSLSAPEGCESACREGCVC 3574
+C CP + Y CG CP SC L C C+ GC C
Sbjct: 3290 YCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVH---CVWRCQPGCYC 3346
Query: 3575 DAGFVLS--GDTCVPVGQCGCLH---DDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPS 3629
G VLS G CV G C CL R++P + P GC+ C C E G ++C
Sbjct: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARP-DGCNH-CTCLE-GRLNCTDL 3403
Query: 3630 SC 3631
C
Sbjct: 3404 PC 3405
Score = 53.5 bits (127), Expect = 5e-06
Identities = 57/200 (28%), Positives = 70/200 (35%), Gaps = 28/200 (14%)
Query: 1480 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVE--PWRTETFCPMECPPNSH 1537
P GP C D+CLG + S CS G H + P + + +C
Sbjct: 3477 PWGPWSPC--DMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQS 3534
Query: 1538 YELCADTCSLGCSALSAPPQCQDG---CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYY 1594
C C C LS CQ G C C C G L CVP C C Y
Sbjct: 3535 LHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QY 3589
Query: 1595 EPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQV-------CQPSGGILSC--VTKDPC 1645
+P + +N + AG E S +PG+V C GIL C V P
Sbjct: 3590 QPGAMGIPENQSRS----AGSRFSSWE-SLEPGEVVTGPCDNCTCVAGILQCQEVPDCPD 3644
Query: 1646 HGV--TCRPQETCKEQGGQG 1663
GV + P E C G G
Sbjct: 3645 PGVWSSWGPWEDCSVSCGGG 3664
Score = 53.5 bits (127), Expect = 5e-06
Identities = 59/224 (26%), Positives = 77/224 (34%), Gaps = 40/224 (17%)
Query: 4632 AGWQVGGAQGCG-ECVSKPC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPA 4688
A W++ AQ +C + C S P Q+ GP SA APC G
Sbjct: 4732 ASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGP-----WSAWSSCSAPCGG----- 4781
Query: 4689 QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC 4748
G + +G PG VA CQA + + CP +CP C
Sbjct: 4782 ----GTMERHRTCEGGPG---------VAPCQAQDTEQRQECNLQPCP-ECPPGQVLSAC 4827
Query: 4749 GDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPL---- 4803
SCP C L C + C+ GC C G +L TCVP C C + L
Sbjct: 4828 ATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTL 4887
Query: 4804 ---GEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
+ PG R C C GA +C++ G
Sbjct: 4888 EEQAQELPPGTVLTRNCT-----RCVCHGGAFSCSLVDCQVPPG 4926
Score = 53.1 bits (126), Expect = 7e-06
Identities = 62/242 (25%), Positives = 79/242 (32%), Gaps = 46/242 (19%)
Query: 1840 WGGSWRAPGWDPLC-WDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP- 1897
W + P W P W +C SC R ++ P T P P
Sbjct: 3177 WPCAEGEPTWSPWTPWSQCSASCGPA---RCHRHRFCARSPSAVPSTVAPLPLPATPTPL 3233
Query: 1898 ---PESFFKGCVLDVC------------------MGGG--DRDILC-----KALASYVAA 1929
PE+ + C+L C GGG R C + L Y
Sbjct: 3234 CSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEG 3293
Query: 1930 CQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQC 1989
+A G V + V T E + Y CG PCP SC C C GC C
Sbjct: 3294 PRAQGEVCQALPCPV-TNCTAIEGAEYSPCGPPCPRSCDDLVH------CVWRCQPGCYC 3346
Query: 1990 DAGFVLSADRCVPLNNG-CGC--WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPA 2046
G VLS++ + + G C C G H G+ C+ C C G L CT
Sbjct: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNH-CTCLE--GRLNCTDL 3403
Query: 2047 SC 2048
C
Sbjct: 3404 PC 3405
Score = 52.8 bits (125), Expect = 9e-06
Identities = 27/81 (33%), Positives = 33/81 (40%), Gaps = 2/81 (2%)
Query: 5134 CQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 5193
C SC C+ C EGC C LL C+P+ +C C S L +
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 5194 CSERCSCSSSSGLTCQAAGCP 5214
CS+ C C L CQ GCP
Sbjct: 2695 CSQ-CVCEKGE-LLCQPGGCP 2713
Score = 52.8 bits (125), Expect = 9e-06
Identities = 35/118 (29%), Positives = 44/118 (37%), Gaps = 18/118 (15%)
Query: 741 CPLSCPANSRY---ELC---GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACV 794
C CP N + E C G CP C C+G C GC C PG +C+
Sbjct: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGF-CAPGCTCPPGLFLHNASCL 2940
Query: 795 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNG 852
P S C C G +++A R +CN TC + ERC V G
Sbjct: 2941 PRSQCPCQLHG-------QLYASGAMARLDSCNNC----TCVSGKMACTSERCPVACG 2987
Score = 52.8 bits (125), Expect = 9e-06
Identities = 58/233 (24%), Positives = 75/233 (32%), Gaps = 55/233 (23%)
Query: 4652 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 4701
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
Query: 4702 QGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSA 4761
G P CP T CQ Q + C CG CP SC LS
Sbjct: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 4762 PEGCESA---CREGCVCDAGFVLSGDTCVPVGQCGCLHD--------------GRYYPLG 4804
C+ C+ C C G + CVP C C + G +
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
Query: 4805 EVFYPGP----ECERRCECGPGGHVTCQEGAAC---------GPHEECRLEDG 4844
E PG C+ C C G + CQE C GP E+C + G
Sbjct: 3612 ESLEPGEVVTGPCD-NCTC-VAGILQCQEVPDCPDPGVWSSWGPWEDCSVSCG 3662
Score = 52.4 bits (124), Expect = 1e-05
Identities = 64/241 (26%), Positives = 85/241 (35%), Gaps = 35/241 (14%)
Query: 1040 CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLP 1099
CG +L A QL +N + P +EC L P A + C P
Sbjct: 4725 CGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQEC-PVLGPWSA-----WSSCSAP 4778
Query: 1100 GQSGPL-----CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCG 1154
G + C+ A CQA + + CP CPP AC+ CP C
Sbjct: 4779 CGGGTMERHRTCEG-GPGVAPCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCW 4836
Query: 1155 DLPVPGGCGSE-CHEGCVCDEGFALSGESCLPLASCGCVHQG-------TYHPPGQTFYP 1206
L C E C GC C G L +C+P +C C T Q P
Sbjct: 4837 HLQPGAICVQEPCQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPP 4896
Query: 1207 GP----GCDSLCHCQEGGLVSCESSSC--GPHEACQP-SGGSLG-----CVAVGSSTCQA 1254
G C + C C GG SC C P E Q + G LG C+ + ++ Q+
Sbjct: 4897 GTVLTRNC-TRCVC-HGGAFSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQS 4954
Query: 1255 S 1255
+
Sbjct: 4955 N 4955
Score = 52.0 bits (123), Expect = 2e-05
Identities = 42/140 (30%), Positives = 48/140 (34%), Gaps = 27/140 (19%)
Query: 1094 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSC 1153
D C P G +C AL C A + Y C CP SC
Sbjct: 3289 DYCEGPRAQGEVCQALPCPVTNCTAIEG------------------AEYSPCGPPCPRSC 3330
Query: 1154 GDLPVPGGCGSECHEGCVCDEGFALS--GESCLPLASCGCVH--QGTYHPPGQTFYPGPG 1209
DL C C GC C G LS G C+ C C+ G H PG G
Sbjct: 3331 DDLV---HCVWRCQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDG 3387
Query: 1210 CDSLCHCQEGGLVSCESSSC 1229
C+ C C EG L +C C
Sbjct: 3388 CNH-CTCLEGRL-NCTDLPC 3405
Score = 51.6 bits (122), Expect = 2e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 12/110 (10%)
Query: 4735 CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCES--ACREGCVCDAGFVLSGDTCVPVGQC 4792
C CPA C + CP C L C+ C++GC C G + CVP+G C
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQDGGCVPIGHC 4117
Query: 4793 GCLHDGRYYPLGEVFYPGPECE---RRCECGPGGHVTCQEGAACGPHEEC 4839
C G + PG + + C C G ++C C P C
Sbjct: 4118 DCTD-----AQGHSWAPGSQHQDACNNCSC-QAGQLSC-TAQPCPPPTHC 4160
Score = 51.2 bits (121), Expect = 3e-05
Identities = 54/213 (25%), Positives = 69/213 (32%), Gaps = 32/213 (15%)
Query: 2250 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 2299
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
Query: 2300 QGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSA 2359
G P CP T CQ Q + C CG CP SC LS
Sbjct: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 2360 PEGCES---ACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD-SLC 2415
C+ C+ C C G + CVP C C + + + G S
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
Query: 2416 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAV 2448
E GEV GP + C G L C V
Sbjct: 3612 ESLEPGEV-----VTGPCDNCTCVAGILQCQEV 3639
Score = 51.2 bits (121), Expect = 3e-05
Identities = 54/213 (25%), Positives = 69/213 (32%), Gaps = 32/213 (15%)
Query: 3451 SPCTPE--------QQESFGGPDACGVISATD--GPLAPCHGLVPPAQYFQGCLLDACQV 3500
+PCT E Q+E+ C V A GP +PC + + + C
Sbjct: 3445 APCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPE 3504
Query: 3501 QGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSA 3560
G P CP T CQ Q + C CG CP SC LS
Sbjct: 3505 GGRP---CPGNHTQSRPCQENSTQCTD----------CGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 3561 PEGCES---ACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD-SLC 3616
C+ C+ C C G + CVP C C + + + G S
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSW 3611
Query: 3617 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAV 3649
E GEV GP + C G L C V
Sbjct: 3612 ESLEPGEV-----VTGPCDNCTCVAGILQCQEV 3639
Score = 50.8 bits (120), Expect = 4e-05
Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 17/116 (14%)
Query: 715 CRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR 774
C G A + C L V NC + + Y CGP CP SC+ +C R
Sbjct: 3291 CEGPRAQGEVCQALPCPV------TNC--TAIEGAEYSPCGPPCPRSCDDLV---HCVWR 3339
Query: 775 PCVEGCVCLPGFVAS--GGACVPASSCGC--TFQGLQLAPGQEVWADELCQRRCTC 826
C GC C PG V S G CV C C G + PG + + C CTC
Sbjct: 3340 -CQPGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGC-NHCTC 3393
Score = 50.8 bits (120), Expect = 4e-05
Identities = 65/247 (26%), Positives = 80/247 (32%), Gaps = 36/247 (14%)
Query: 3836 CPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 3895
CP G P E ++Q+E S T P+ P GP C D+CL
Sbjct: 3437 CPTPQHGGAPCTGEAGEAGAQHQRE---ACPSYATCPVDGAW---GPWGPWSPC--DMCL 3488
Query: 3896 GGGNLSILCSNIHAYVSACQAAGGHVEP---WRNETFCPMECPQNSHYELCADTCSLGCS 3952
G + S CS G H + N T C +C C C C
Sbjct: 3489 GQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCT-DCGGGQSLHPCGQPCPRSCQ 3547
Query: 3953 ALSAPLQCPDG---CAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQ 4009
LS C G C C C G L CVP C C Y+P + +N +
Sbjct: 3548 DLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRC-----QYQPGAMGIPENQSR 3602
Query: 4010 QCTCHVGKVVVCQEHSCKPGQV-------CQPSGGILSC--VTKDPCHGV--TCRPQETC 4058
S +PG+V C GIL C V P GV + P E C
Sbjct: 3603 SAGSRFS-----SWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDC 3657
Query: 4059 KEQGGQG 4065
G G
Sbjct: 3658 SVSCGGG 3664
Score = 50.4 bits (119), Expect = 5e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 1963 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 2021
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
Query: 2022 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 2081
W + S C G + C+P +C GE L P C P E P
Sbjct: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
Query: 2082 TLDGHRFNFQGTC 2094
L R +GTC
Sbjct: 5055 LLTELRNFTKGTC 5067
Score = 50.4 bits (119), Expect = 5e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 3164 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 3222
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
Query: 3223 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 3282
W + S C G + C+P +C GE L P C P E P
Sbjct: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
Query: 3283 TLDGHRFDFQGTC 3295
L R +GTC
Sbjct: 5055 LLTELRNFTKGTC 5067
Score = 50.4 bits (119), Expect = 5e-05
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 6/133 (4%)
Query: 4365 CPASCPSPAPLTTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSE 4423
C +C T + C GC C G F A CVP ++ C CW G H GSE
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDH-CECWHLGRPHLPGSE 4998
Query: 4424 FWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYV 4483
W + S C G + C+P +C GE L P C P E P
Sbjct: 4999 -WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG---SCCPSCRREAPEEQSPSCQ 5054
Query: 4484 TLDGHRFDFQGTC 4496
L R +GTC
Sbjct: 5055 LLTELRNFTKGTC 5067
Score = 49.7 bits (117), Expect = 8e-05
Identities = 159/676 (23%), Positives = 209/676 (30%), Gaps = 146/676 (21%)
Query: 2241 GECVSKPCPSPCTPEQQESFGGPD-ACGVISATDGPLAP----CHG-------------- 2281
G V + C C P E P C V++ +G P HG
Sbjct: 1277 GGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHGGACLEPASCPCEWG 1336
Query: 2282 --LVPPAQYFQ-GCLLDACQV-QGHPGG-------LCPAVATYVAACQAAGAQLREWRRP 2330
PP Q C CQ Q H GG L PA A A CQ G
Sbjct: 1337 RNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEALCQENG--------- 1387
Query: 2331 DFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCES-ACREG-CVCDAGFVLS-GDTCVPV 2387
C H LC + C S EGC + C EG C +G L C
Sbjct: 1388 -----HCVPHGW--LCDNQ--DDCGDGSDEEGCAAPGCGEGQMTCSSGHCLPLALLCDRQ 1438
Query: 2388 GQCGCLHDDRYYPL---------GQTFYPGPGCDSLCRCREG--------------GEVS 2424
CG D+ YP G+ P CD C + GEVS
Sbjct: 1439 DDCGDGTDEPSYPCPQGLLACADGRCLPPALLCDGHPDCLDAADEESCLGQVTCVPGEVS 1498
Query: 2425 CEPSSC-GPHETCR-----PSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYV 2478
C +C G + C P G G G + P +T G + T
Sbjct: 1499 CVDGTCLGAIQLCDGVWDCPDGADEG---PGHCPLPSLPTPPASTLPGPSPGSLDTASSP 1555
Query: 2479 LAQTCGTRP-GLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR--------QWK 2529
LA P G F G+G + Q + ++R
Sbjct: 1556 LASASPAPPCGPFEFRC-------GSGECTPRGWRCDQEEDCADGSDERGCGGPCAPHHA 1608
Query: 2530 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCG 2589
G P L +G +R GSD + GL L R +P Y G
Sbjct: 1609 PCARGPHCVSPEQLCDG-VRQCPDGSDEGPDACGGLPA---LGGPNRTGLPCPEYTCPNG 1664
Query: 2590 LCGNYN--GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEG----CI 2643
C + D + D +P + +W P PC TC P +G C
Sbjct: 1665 TCIGFQLVCDGQPDCGRPGQVGPSPEEQGCGAWGPWSPWGPC--SRTCGPWGQGRSRRCS 1722
Query: 2644 PS-----EECP-PELEKKYQKEEFCGLLS--SPTGPLSSCHKLVDPQGPLKDCIFDLCLG 2695
P + CP PE + + C + S P S C + C G
Sbjct: 1723 PLGLLVLQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCS--------------EPCRG 1768
Query: 2696 GGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPME------CPQNSHYELCADTCSLG 2749
C + C A G + R CP + C ++ CA C L
Sbjct: 1769 TMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLT 1827
Query: 2750 CSALSAPLQCPDGC---AEGCQCDSGFLYNGQA-CVPIQQCGCYHNGAYYEPEQTVLIDN 2805
C +S + CP + GC C G + + CV +QC C +GA Y P Q + D
Sbjct: 1828 CDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD- 1886
Query: 2806 CRQQCTCHVGKVVVCQ 2821
C Q C C G+ C+
Sbjct: 1887 C-QLCICQDGRPRRCR 1901
Score = 49.7 bits (117), Expect = 8e-05
Identities = 22/46 (47%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 756 PACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
P CP SC A +CSG CVEGC C PG + C+P S C C
Sbjct: 2633 PPCPPSCLDPKANRSCSGH-CVEGCRCPPGLLLHDTRCLPLSECPC 2677
Score = 49.7 bits (117), Expect = 8e-05
Identities = 70/267 (26%), Positives = 83/267 (31%), Gaps = 54/267 (20%)
Query: 2635 CPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 2694
CP G P E ++Q+E S T P+ P GP C D+CL
Sbjct: 3437 CPTPQHGGAPCTGEAGEAGAQHQRE---ACPSYATCPVDGAW---GPWGPWSPC--DMCL 3488
Query: 2695 GGGNLSILCSNIHAYVSACQAAGGQVEP---WRNETFCPMECPQNSHYELCADTCSLGCS 2751
G + S CS G + N T C +C C C C
Sbjct: 3489 GQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCT-DCGGGQSLHPCGQPCPRSCQ 3547
Query: 2752 ALSAPLQCPDG---CAEGCQCDSGFLYNGQACVPIQQCGC-YHNGAYYEPEQ-------- 2799
LS C G C C C G L CVP C C Y GA PE
Sbjct: 3548 DLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSR 3607
Query: 2800 ----------TVLIDNCRQQCTCHVGKVVVCQE----------HSCKPGQVCQPSGG--- 2836
V+ C CTC G ++ CQE S P + C S G
Sbjct: 3608 FSSWESLEPGEVVTGPC-DNCTCVAG-ILQCQEVPDCPDPGVWSSWGPWEDCSVSCGGGE 3665
Query: 2837 ---ILSCVNKDPCHGVTCRPQETCKEQ 2860
C + PC G R TC Q
Sbjct: 3666 QLRSRRCA-RPPCPG-PARQSRTCSTQ 3690
Score = 48.5 bits (114), Expect = 2e-04
Identities = 27/77 (35%), Positives = 32/77 (41%), Gaps = 5/77 (6%)
Query: 4752 CPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP 4811
CP SC A C C EGC C G +L C+P+ +C CL G F G
Sbjct: 2635 CPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLGN 2694
Query: 4812 ECERRCE-----CGPGG 4823
+ CE C PGG
Sbjct: 2695 CSQCVCEKGELLCQPGG 2711
Score = 48.5 bits (114), Expect = 2e-04
Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 10/121 (8%)
Query: 3914 CQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD--GCAEGCQCD 3971
C GH P C + C C+ C+ + C D C GC C
Sbjct: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
Query: 3972 SGFLYNGQACVPIQQCGCYHN-----GVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 4026
G L C+P ++C C+H G+ P + + C+ +C C G+ + C C
Sbjct: 4463 KGLLEQAGGCIPPEECNCWHTSAAGAGMTLAPGDRLQL-GCK-ECECRRGE-LHCTSQGC 4519
Query: 4027 K 4027
+
Sbjct: 4520 Q 4520
Score = 47.4 bits (111), Expect = 4e-04
Identities = 34/130 (26%), Positives = 47/130 (36%), Gaps = 9/130 (6%)
Query: 5091 CRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQ--GSCAALSGLTG-- 5146
C SLA C + T C CP + + + Q G C L G
Sbjct: 2857 CSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPG 2915
Query: 5147 --CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 5204
CT C GC C L C+P C C +G+ L + ++ D C+C S
Sbjct: 2916 IECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQ-LYASGAMARLDSCNNCTCVSGK 2974
Query: 5205 GLTCQAAGCP 5214
+ C + CP
Sbjct: 2975 -MACTSERCP 2983
Score = 47.4 bits (111), Expect = 4e-04
Identities = 38/144 (26%), Positives = 52/144 (36%), Gaps = 19/144 (13%)
Query: 742 PLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801
P CP + ++ C P SC +AP + + C GC C G + CVP C C
Sbjct: 3087 PGMCPRDKQWLDCAQG-PASCAELSAPRG-TNQTCHPGCHCPSGMLLLNNVCVPTQDCPC 3144
Query: 802 TFQGLQLAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAGE----------RCSVQ 850
+G PG V R C C+ + + C GE +CS
Sbjct: 3145 AHEGHLYPPGSTV------VRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQCSAS 3198
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVS 874
G C+ RF S P V+
Sbjct: 3199 CGPARCHRHRFCARSPSAVPSTVA 3222
Score = 47.4 bits (111), Expect = 4e-04
Identities = 35/115 (30%), Positives = 45/115 (39%), Gaps = 13/115 (11%)
Query: 1947 EITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 2004
E +C + CGSPC C A + +C+ PC GC C G + A C+P
Sbjct: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
Query: 2005 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 2058
C CW + + AG C+ C G L CT C GLLP
Sbjct: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
Score = 47.0 bits (110), Expect = 5e-04
Identities = 49/189 (25%), Positives = 66/189 (34%), Gaps = 42/189 (22%)
Query: 2608 SQAGNANEFGNSWEEVVPDSPCLPPP---TCPPGSEGCIPSEECPPELEKKYQKEEFCGL 2664
+Q+ +A +SWE + P P TC G C +CP G+
Sbjct: 3599 NQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDP-----------GV 3647
Query: 2665 LSSPTGPLSSCHKLVDPQGPLKD--CIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEP 2722
SS GP C L+ C C G S CS C+ AG
Sbjct: 3648 WSS-WGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCST-----QVCREAG----- 3696
Query: 2723 WRNETFCPMECPQNSHYELC--ADTCSLGCSALSAPLQC-PDGCAEGCQCDSGFLYNGQA 2779
CP Y C + C C+ ++ + C +GC EGC C G + A
Sbjct: 3697 ----------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA 3746
Query: 2780 CVPIQQCGC 2788
CV Q+C C
Sbjct: 3747 CV--QECPC 3753
Score = 47.0 bits (110), Expect = 5e-04
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 13/126 (10%)
Query: 5099 AACQAAGVAVKPWRTDSF----CPLHCPAHSHYSI--CTRTCQGSCAALSGLTGCTTR-C 5151
A G +PW +S CP C A C C SCA L C C
Sbjct: 4642 AEALCGGGCREPWAQESCNGGPCP-ECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPC 4700
Query: 5152 FEGCECDDRFLLSQGVCIPVQDCGC---THNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 5208
GC C L+ G C+P+ C C + N + + + DC + C+C + S L C
Sbjct: 4701 RPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWELAPAQAVQLDC-QNCTCVNES-LVC 4758
Query: 5209 QAAGCP 5214
CP
Sbjct: 4759 PHQECP 4764
Score = 47.0 bits (110), Expect = 5e-04
Identities = 60/230 (26%), Positives = 82/230 (35%), Gaps = 37/230 (16%)
Query: 640 WKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPF--- 696
W L G ++ CQ C C GQ H + C P C T P+
Sbjct: 4836 WHLQPGAICVQEPCQPGC-GCPGGQLLH---NGTCV-------PPTACPCTQHSLPWGLT 4884
Query: 697 --LEQCVYDL----CVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLSCPANS 749
LE+ +L + +C G A++ + ++ + G+ W+ A L
Sbjct: 4885 LTLEEQAQELPPGTVLTRNCTRCVCHG-GAFSCSLVDCQVPPGETWQQVAPGELG----- 4938
Query: 750 RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASSCGCTFQGLQL 808
LC C N SNCS GCVC PG F + G CVP C C G
Sbjct: 4939 ---LCEQTC-LEMNATKTQSNCSSARA-SGCVCQPGHFRSQAGPCVPEDHCECWHLGRPH 4993
Query: 809 APGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYP 858
PG E W E C+ +G +C GE ++ G C P
Sbjct: 4994 LPGSE-W-QEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG--SCCP 5039
Score = 46.6 bits (109), Expect = 7e-04
Identities = 35/119 (29%), Positives = 49/119 (41%), Gaps = 13/119 (10%)
Query: 3914 CQAAGGHVEPWRNETFCPME------CPQNSHYELCADTCSLGCSALSAPLQCPDGC--- 3964
C A G + R CP + C ++ CA C L C +S + CP
Sbjct: 1786 CAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCG 1844
Query: 3965 AEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQ 4022
+ GC C G + + CV +QC C +G Y P Q + D C Q C C G+ C+
Sbjct: 1845 SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD-C-QLCICQDGRPRRCR 1901
Score = 46.6 bits (109), Expect = 7e-04
Identities = 49/189 (25%), Positives = 65/189 (34%), Gaps = 42/189 (22%)
Query: 3809 SQAGNANEFGNSWEEVVPDSPCLPPP---TCPPGSAGCIPSDKCPPELEKKYQKEEFCGL 3865
+Q+ +A +SWE + P P TC G C CP G+
Sbjct: 3599 NQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDP-----------GV 3647
Query: 3866 LSSPTGPLSSCHKLVDPQGPLKD--CIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEP 3923
SS GP C L+ C C G S CS C+ AG
Sbjct: 3648 WSS-WGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCST-----QVCREAG----- 3696
Query: 3924 WRNETFCPMECPQNSHYELC--ADTCSLGCSALSAPLQC-PDGCAEGCQCDSGFLYNGQA 3980
CP Y C + C C+ ++ + C +GC EGC C G + A
Sbjct: 3697 ----------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA 3746
Query: 3981 CVPIQQCGC 3989
CV Q+C C
Sbjct: 3747 CV--QECPC 3753
Score = 46.6 bits (109), Expect = 7e-04
Identities = 48/181 (26%), Positives = 66/181 (36%), Gaps = 25/181 (13%)
Query: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT----CPEN 1953
P S + C G +R C+ VA CQA +D + C + CP
Sbjct: 4768 PWSAWSSCSAPCGGGTMERHRTCEG-GPGVAPCQA-----QDTEQRQECNLQPCPECPPG 4821
Query: 1954 SHYEVCGSPCPASCPSPAPLTTPAVC-EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWAN 2012
C + CP C P A+C + PC GC C G +L CVP C C +
Sbjct: 4822 QVLSACATSCPCLCWHLQP---GAICVQEPCQPGCGCPGGQLLHNGTCVP-PTACPCTQH 4877
Query: 2013 G-------TYHEAGSEFWADGTCSQWC-RCGPGGGSLVCTPASCGL--GEVCGLLPSGQH 2062
T E E ++ C RC GG+ C+ C + GE + G+
Sbjct: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
Query: 2063 G 2063
G
Sbjct: 4938 G 4938
Score = 46.6 bits (109), Expect = 7e-04
Identities = 49/194 (25%), Positives = 65/194 (33%), Gaps = 31/194 (15%)
Query: 5099 AACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTR-CFEGCEC 5157
A CQA + CP CP S C +C C L C C GC C
Sbjct: 4797 APCQAQDTEQRQECNLQPCP-ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGC 4855
Query: 5158 DDRFLLSQGVCIPVQDCGCTHN-------------GRYLPVNSSLLTSDCSERCSCSSSS 5204
LL G C+P C CT + + LP ++LT +C+ RC C +
Sbjct: 4856 PGGQLLHNGTCVPPTACPCTQHSLPWGLTLTLEEQAQELP-PGTVLTRNCT-RCVCHGGA 4913
Query: 5205 GLTCQAAGC--PPGR-----------VCEVKAEARNCWATRGLCVLSVGANLTTFDGARG 5251
+C C PPG +CE N T+ C + + G
Sbjct: 4914 -FSCSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPGHFR 4972
Query: 5252 ATTSPGVYELSSRC 5265
+ P V E C
Sbjct: 4973 SQAGPCVPEDHCEC 4986
Score = 45.8 bits (107), Expect = 0.001
Identities = 38/158 (24%), Positives = 52/158 (32%), Gaps = 23/158 (14%)
Query: 2713 CQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPD--GCAEGCQCD 2770
C G P C + C C+ C+ + C D C GC C
Sbjct: 4403 CTRLDGHFRPCLISNCSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCP 4462
Query: 2771 SGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQV 2830
G L C+P ++C C+H A L R Q + C+E C+ G++
Sbjct: 4463 KGLLEQAGGCIPPEECNCWHTSA--AGAGMTLAPGDRLQ--------LGCKECECRRGEL 4512
Query: 2831 CQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLP 2868
S G C G+ P E G CLP
Sbjct: 4513 HCTSQG---------CQGLL--PLSEWSEWSPCGPCLP 4539
Score = 45.8 bits (107), Expect = 0.001
Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 25/181 (13%)
Query: 3099 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT----CPEN 3154
P S + C G +R C+ VA CQA +D + C + CP
Sbjct: 4768 PWSAWSSCSAPCGGGTMERHRTCEG-GPGVAPCQA-----QDTEQRQECNLQPCPECPPG 4821
Query: 3155 SHYEVCGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWAN 3213
C CP C P A+C + PC GC C G +L CVP C C +
Sbjct: 4822 QVLSACATSCPCLCWHLQP---GAICVQEPCQPGCGCPGGQLLHNGTCVP-PTACPCTQH 4877
Query: 3214 G-------TYHEAGSEFWADGTCSQWC-RCGPGGGSLVCTPASCGL--GEVCGLLPSGQH 3263
T E E ++ C RC GG+ C+ C + GE + G+
Sbjct: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
Query: 3264 G 3264
G
Sbjct: 4938 G 4938
Score = 45.8 bits (107), Expect = 0.001
Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 25/181 (13%)
Query: 4300 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT----CPEN 4355
P S + C G +R C+ VA CQA +D + C + CP
Sbjct: 4768 PWSAWSSCSAPCGGGTMERHRTCEG-GPGVAPCQA-----QDTEQRQECNLQPCPECPPG 4821
Query: 4356 SHYEVCGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCDAGFVLSADRCVPLNNGCGCWAN 4414
C CP C P A+C + PC GC C G +L CVP C C +
Sbjct: 4822 QVLSACATSCPCLCWHLQP---GAICVQEPCQPGCGCPGGQLLHNGTCVP-PTACPCTQH 4877
Query: 4415 G-------TYHEAGSEFWADGTCSQWC-RCGPGGGSLVCTPASCGL--GEVCGLLPSGQH 4464
T E E ++ C RC GG+ C+ C + GE + G+
Sbjct: 4878 SLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPGEL 4937
Query: 4465 G 4465
G
Sbjct: 4938 G 4938
Score = 45.8 bits (107), Expect = 0.001
Identities = 35/102 (34%), Positives = 41/102 (40%), Gaps = 15/102 (14%)
Query: 4752 CPVSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDGRYYPLGEVF 4807
C +C ++A + C SA GCVC G F CVP C C H LG
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
Query: 4808 YPGPECERRCE---CGPGGHVTCQEGA--ACGPHEECRLEDG 4844
PG E + CE C G V Q + C EE LE G
Sbjct: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPG 5035
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/98 (34%), Positives = 43/98 (43%), Gaps = 12/98 (12%)
Query: 741 CP-LSCPANSRYELCGPACPTSCNGAAAPSNCSGR-PCVE-GCVCLPGFV-ASGGACVPA 796
CP +C ++ C P CP +C+ + C PC GC C G V S G CV
Sbjct: 1807 CPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWP 1865
Query: 797 SSCGCTFQGLQLAPGQEVWAD-ELC------QRRCTCN 827
C C G + PGQ + AD +LC RRC N
Sbjct: 1866 RQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLN 1903
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 3148 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 3205
E +C + CG PC C A + +C+ PC GC C G + A C+P
Sbjct: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
Query: 3206 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 3259
C CW + + AG C+ C G L CT C GLLP
Sbjct: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
Score = 45.4 bits (106), Expect = 0.001
Identities = 34/115 (29%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Query: 4349 EITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEG--PCVEGCQCDAGFVLSADRCVPLN 4406
E +C + CG PC C A + +C+ PC GC C G + A C+P
Sbjct: 4420 EDSCTPPFEFHACGSPCAGLC---ATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPE 4476
Query: 4407 NGCGCWANGTYHEAGSEFWADGTCSQWCR-CGPGGGSLVCTPASCGLGEVCGLLP 4460
C CW + + AG C+ C G L CT C GLLP
Sbjct: 4477 E-CNCW-HTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQ-----GLLP 4524
Score = 45.4 bits (106), Expect = 0.001
Identities = 41/121 (33%), Positives = 54/121 (44%), Gaps = 19/121 (15%)
Query: 1938 EDWRAQVGCEI-TCPENSHYEV-----CGSPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 1990
E W AQ C CPE + C + CP SC A L C +GPC GC+C
Sbjct: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
Query: 1991 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 2047
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
Query: 2048 C 2048
C
Sbjct: 4763 C 4763
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 31/111 (27%)
Query: 2350 CPGSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDDRYYPLGQTF 2405
C +C ++A + C SA GCVC G F CVP C C H LG+
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
Query: 2406 YPG----------------PGCDSLC---RCREGGEVSCEPSSCGPHETCR 2437
PG P C C C +G E+ EP SC P +CR
Sbjct: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCP--SCR 5042
Score = 45.4 bits (106), Expect = 0.001
Identities = 35/111 (31%), Positives = 43/111 (38%), Gaps = 31/111 (27%)
Query: 3551 CPGSCPSLSAPE---GCESACREGCVCDAG-FVLSGDTCVPVGQCGCLHDDRYYPLGQTF 3606
C +C ++A + C SA GCVC G F CVP C C H LG+
Sbjct: 4940 CEQTCLEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWH------LGRPH 4993
Query: 3607 YPG----------------PGCDSLC---RCREGGEVSCEPSSCGPHETCR 3638
PG P C C C +G E+ EP SC P +CR
Sbjct: 4994 LPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCP--SCR 5042
Score = 45.1 bits (105), Expect = 0.002
Identities = 37/120 (30%), Positives = 51/120 (42%), Gaps = 15/120 (12%)
Query: 1512 CQAAGGHVEPWRTETFCPMECPPNSH------YELCADTCSLGCSALSA----PPQCQDG 1561
C A G + R CP + PN+ ++ CA C L C +S PP G
Sbjct: 1786 CAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPPDWPCG 1844
Query: 1562 CAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQ 1620
+ GC C G + + CV +QC C +G Y P Q + D C Q C C G+ C+
Sbjct: 1845 -SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD-C-QLCICQDGRPRRCR 1901
Score = 45.1 bits (105), Expect = 0.002
Identities = 64/269 (23%), Positives = 87/269 (32%), Gaps = 76/269 (28%)
Query: 2218 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 2277
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
Query: 2278 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLREW 2327
P G+ ++ C + C PG + C+ AG
Sbjct: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
Query: 2328 RRPDFCPFQCPAHSHYELC--GDSCPGSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 2384
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
Query: 2385 VPVGQC----------GCLHDDRYYPLGQTFYPGPGCDS---------LCRCREGGEVSC 2425
V C G D PLG PG DS C C G++SC
Sbjct: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSCGNCSCAH-GKLSC 3802
Query: 2426 EPSSC----------GPHETCRPSGGSLG 2444
C P C S G LG
Sbjct: 3803 SLDDCFEADGGFGPWSPWGPCSRSCGGLG 3831
Score = 45.1 bits (105), Expect = 0.002
Identities = 64/269 (23%), Positives = 87/269 (32%), Gaps = 76/269 (28%)
Query: 3419 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 3478
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
Query: 3479 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLREW 3528
P G+ ++ C + C PG + C+ AG
Sbjct: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
Query: 3529 RRPDFCPFQCPAHSHYELC--GDSCPGSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 3585
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
Query: 3586 VPVGQC----------GCLHDDRYYPLGQTFYPGPGCDS---------LCRCREGGEVSC 3626
V C G D PLG PG DS C C G++SC
Sbjct: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSCGNCSCAH-GKLSC 3802
Query: 3627 EPSSC----------GPHETCRPSGGSLG 3645
C P C S G LG
Sbjct: 3803 SLDDCFEADGGFGPWSPWGPCSRSCGGLG 3831
Score = 45.1 bits (105), Expect = 0.002
Identities = 32/106 (30%), Positives = 40/106 (37%), Gaps = 15/106 (14%)
Query: 745 CPANSRYELCGPA--CPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSC--- 799
CPA Y C P CP SC C C EGC C G ACV C
Sbjct: 3697 CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLACVQECPCVLT 3756
Query: 800 -------GCTF--QGLQLAPGQEVWADELCQRRC-TCNGATHQVTC 835
G T G L PG E+ + + + C C+ A +++C
Sbjct: 3757 AWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802
Score = 45.1 bits (105), Expect = 0.002
Identities = 51/222 (22%), Positives = 68/222 (30%), Gaps = 73/222 (32%)
Query: 4645 CVSKPCPSPCT---------------PEQQESFGGPDACGVISATDGPLAPCHGLVPPAQ 4689
C S PCP C +Q+ GP + G + APC L
Sbjct: 4357 CYSGPCPEECVWSSWSSWTRCSCRVLVQQRYRHQGPASRGARAG-----APCTRL---DG 4408
Query: 4690 YFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCG 4749
+F+ CL+ C P + AG C H ++LC
Sbjct: 4409 HFRPCLISNCS----EDSCTPPFEFHACGSPCAGL--------------CATHLSHQLCQ 4450
Query: 4750 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYP 4809
D P C+ GC C G + C+P +C C H G P
Sbjct: 4451 DLPP---------------CQPGCYCPKGLLEQAGGCIPPEECNCWHTSA-AGAGMTLAP 4494
Query: 4810 GPECE---RRCECGPGG-HVTCQ------------EGAACGP 4835
G + + CEC G H T Q E + CGP
Sbjct: 4495 GDRLQLGCKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGP 4536
Score = 44.7 bits (104), Expect = 0.003
Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 14/96 (14%)
Query: 4748 CGDSCPVSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEV 4806
C + CP SC L C + CR GC C G ++ CVP+ C C P
Sbjct: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC-----GLPSANA 4732
Query: 4807 FY---PGPECERRCECGPGGHVTCQEGAACGPHEEC 4839
+ P + C+ + TC + PH+EC
Sbjct: 4733 SWELAPAQAVQLDCQ-----NCTCVNESLVCPHQEC 4763
Score = 44.3 bits (103), Expect = 0.003
Identities = 147/647 (22%), Positives = 199/647 (30%), Gaps = 152/647 (23%)
Query: 4645 CVSKPCPSP----CTPEQQ--ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL-- 4696
C +PC P C ++Q + GP +C +SA G CH P G LL
Sbjct: 3077 CGLQPCAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTNQTCH---PGCHCPSGMLLLN 3133
Query: 4697 --------DACQVQGH---PGGL-------CPAVATYVAACQAAGAQLGE-----WRRPD 4733
C +GH PG C V+ +A C + GE W
Sbjct: 3134 NVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWS 3193
Query: 4734 FCPLQC-PAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQ 4791
C C PA H + C S P + PS AP + C +G + C+ G
Sbjct: 3194 QCSASCGPARCHRHRFCARS-PSAVPSTVAPLPLPATPTPLC---SGPEAEEEPCLLQG- 3248
Query: 4792 CGCLHDGRYYPLGEVFYPGPECERRCECGPGGHV-TCQEGAACGPHEECRLEDGVQA--- 4847
C G + P G P C R C G C + G + C +G +A
Sbjct: 3249 --CDRAGGWGPWG----PWSHCSRSCGGGLRSRTRACDQPPPQGLGDYC---EGPRAQGE 3299
Query: 4848 -CHATGCG--RCLANGGIHYITLDG---RVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK 4901
C A C C A G Y R D C + C+ PG VL
Sbjct: 3300 VCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQ-----VLSS 3354
Query: 4902 NAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 4961
N A +Q + + L GQ+ G +A P EGR L T
Sbjct: 3355 NGAICVQPGHCSC----LDLLTGQRHH-PGARLARPDGCNHC-TCLEGR---LNCT---- 3401
Query: 4962 LLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSS 5021
+P P G C WS+ + + + + A P
Sbjct: 3402 -----------DLPCPVPGGWCP--------WSE-WTMCSQPCRGQTRSRSRACACPTPQ 3441
Query: 5022 KGCGEGCGPQGCPVCLAEETAPYESNEACGQLRN--------PQGPFATCQAVLSPSEYF 5073
G G G E EAC P GP++ C L S
Sbjct: 3442 HGGAPCTGEAG-------EAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRS 3494
Query: 5074 RQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRT 5133
R C + G C +P + +S C C +
Sbjct: 3495 RACSRPPTPEGG-------------RPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQP 3541
Query: 5134 CQGSCAALSGLTGC---TTRCFEGCECDDRFLLSQGVCIPVQDCGCTH--NGRYLPVNSS 5188
C SC LS + C + C C C L G+C+P C C + +P N S
Sbjct: 3542 CPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQS 3601
Query: 5189 -----------------LLTSDCSERCSCSSSSGLTCQ-AAGCP-PG 5216
++T C + C+C + L CQ CP PG
Sbjct: 3602 RSAGSRFSSWESLEPGEVVTGPC-DNCTCVAGI-LQCQEVPDCPDPG 3646
Score = 44.3 bits (103), Expect = 0.003
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 3139 EDWRAQVGCEI-TCPENSHYEV-----CGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 3191
E W AQ C CPE + C CP SC A L C +GPC GC+C
Sbjct: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
Query: 3192 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 3248
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
Query: 3249 C 3249
C
Sbjct: 4763 C 4763
Score = 44.3 bits (103), Expect = 0.003
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 19/121 (15%)
Query: 4340 EDWRAQVGCEI-TCPENSHYEV-----CGPPCPASCPSPAPLTTPAVC-EGPCVEGCQCD 4392
E W AQ C CPE + C CP SC A L C +GPC GC+C
Sbjct: 4652 EPW-AQESCNGGPCPECEAQDTVFTLDCANQCPHSC---ADLWDRVQCLQGPCRPGCRCP 4707
Query: 4393 AGFVLSADRCVPLNNGCGCW---ANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 4449
G ++ RCVP+++ C C AN ++ A ++ A Q C C SLVC
Sbjct: 4708 PGQLVQDGRCVPISS-CRCGLPSANASWELAPAQ--AVQLDCQNCTC--VNESLVCPHQE 4762
Query: 4450 C 4450
C
Sbjct: 4763 C 4763
Score = 43.9 bits (102), Expect = 0.004
Identities = 52/200 (26%), Positives = 68/200 (34%), Gaps = 48/200 (24%)
Query: 1428 CLPPTPCPPG--SED--CIPSHKCP----------PELEKKYQKEEFCGLLSSP-----T 1468
C P CP G S+D C+P C PE + + F S T
Sbjct: 3562 CQPTCGCPLGQLSQDGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVT 3621
Query: 1469 GPLSSCHKLV------------DPQ-----GPLKDCIFDLCLGGGNL-SILCSNIHAYVS 1510
GP +C + DP GP +DC C GG L S C+
Sbjct: 3622 GPCDNCTCVAGILQCQEVPDCPDPGVWSSWGPWEDCSVS-CGGGEQLRSRRCAR-----P 3675
Query: 1511 ACQAAGGHVEPWRTETFCPMECPPNSHYELC--ADTCSLGCSALSAPPQC-QDGCAEGCQ 1567
C T+ CP Y C + C C+ ++ C +GC EGC
Sbjct: 3676 PCPGPARQSRTCSTQVCREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCH 3735
Query: 1568 CDSGFLYNGQACVPIQQCGC 1587
C G + ACV Q+C C
Sbjct: 3736 CPEGTFQHRLACV--QECPC 3753
Score = 43.1 bits (100), Expect = 0.007
Identities = 33/133 (24%), Positives = 46/133 (34%), Gaps = 10/133 (7%)
Query: 1103 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSY------GCPLSCGDL 1156
G C +LA C + ++ C CP + + + CP C
Sbjct: 2854 GRSCSSLAPGDTTCPGPHSQTRDCNTQP-CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQ 2912
Query: 1157 PVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC 1216
C C GC C G L SCLP + C C G + G C++ C C
Sbjct: 2913 GPGIECTGFCAPGCTCPPGLFLHNASCLPRSQCPCQLHGQLYASG-AMARLDSCNN-CTC 2970
Query: 1217 QEGGLVSCESSSC 1229
G + +C S C
Sbjct: 2971 VSGKM-ACTSERC 2982
Score = 43.1 bits (100), Expect = 0.007
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 2346 CGDSCPGSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGC 2392
C + CP SC L C + CR GC C G ++ CVP+ C C
Sbjct: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC 4725
Score = 43.1 bits (100), Expect = 0.007
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 1/48 (2%)
Query: 3547 CGDSCPGSCPSLSAPEGC-ESACREGCVCDAGFVLSGDTCVPVGQCGC 3593
C + CP SC L C + CR GC C G ++ CVP+ C C
Sbjct: 4678 CANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRC 4725
Score = 42.7 bits (99), Expect = 0.010
Identities = 29/105 (27%), Positives = 37/105 (35%), Gaps = 14/105 (13%)
Query: 714 LCRGLSAYAQACLELGISVGDWRSPANCPLS------------CPANSRYELCGPACPTS 761
+C G S ++AC G P N S C CG CP S
Sbjct: 3486 MCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRS 3545
Query: 762 CNGAAAPSNCSGRP--CVEGCVCLPGFVASGGACVPASSCGCTFQ 804
C + S C C C C G ++ G CVP + C C +Q
Sbjct: 3546 CQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQ 3590
Score = 42.7 bits (99), Expect = 0.010
Identities = 58/252 (23%), Positives = 84/252 (33%), Gaps = 63/252 (25%)
Query: 4620 PADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 4679
P + ++ G + + W+ + GE V+ PC + CT G++ + P
Sbjct: 3597 PENQSRSAGSRFSSWE---SLEPGEVVTGPCDN-CTC----------VAGILQCQEVPDC 3642
Query: 4680 PCHGLVPPAQYFQGCLLDA----------CQVQGHPGGLCPAVATYVAACQAAGAQLGEW 4729
P G+ ++ C + C PG + C+ AG
Sbjct: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAG------ 3696
Query: 4730 RRPDFCPLQCPAHSHYELC--GDSCPVSCPSLSAPEGCES-ACREGCVCDAGFVLSGDTC 4786
CPA Y C G+ CP SC ++ GC S C EGC C G C
Sbjct: 3697 ---------CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC 3747
Query: 4787 VPVGQC----------GCLHDGRYYPLGEVFYPGPECER----RCECGPGGHVTCQEGAA 4832
V C G PLG PG E + R C G+ +C G
Sbjct: 3748 VQECPCVLTAWLLQELGATIGDPGQPLG----PGDELDSGQTLRTSC---GNCSCAHGKL 3800
Query: 4833 CGPHEECRLEDG 4844
++C DG
Sbjct: 3801 SCSLDDCFEADG 3812
Score = 42.0 bits (97), Expect = 0.017
Identities = 25/84 (29%), Positives = 31/84 (36%), Gaps = 6/84 (7%)
Query: 1114 AACQAAGATVHPWRSEELCPLSCPPHSHYEA-----CSYGCPLSCGDLPVPGGC-GSECH 1167
A G PW E CP + C+ CP SC DL C C
Sbjct: 4642 AEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCR 4701
Query: 1168 EGCVCDEGFALSGESCLPLASCGC 1191
GC C G + C+P++SC C
Sbjct: 4702 PGCRCPPGQLVQDGRCVPISSCRC 4725
Score = 41.6 bits (96), Expect = 0.022
Identities = 73/320 (22%), Positives = 95/320 (29%), Gaps = 94/320 (29%)
Query: 1018 GGGQAANALAFGNSWQEETRPG---CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGP 1074
GGG S E + G C PG CP+ D Q C L+ P+G
Sbjct: 3057 GGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPR-DKQWLDCAQGPASCAELSAPRGT 3115
Query: 1075 FRECHSKLD-PQGAVR-----------DCVYDRCLLPGQSGPL-----CDALATYAAACQ 1117
+ CH P G + C ++ L P S + C ++ A C
Sbjct: 3116 NQTCHPGCHCPSGMLLLNNVCVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCS 3175
Query: 1118 A-----AGATVHPWRSEELCPLSCPP-----HSHYEACSYGCPLSCGDLPVP-------- 1159
+ T PW C SC P H P + LP+P
Sbjct: 3176 SWPCAEGEPTWSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCS 3235
Query: 1160 -----------------GGCG-----SECHEGC---------VCD-----------EGFA 1177
GG G S C C CD EG
Sbjct: 3236 GPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPR 3295
Query: 1178 LSGESC----LPLASCGCVHQGTYHPPGQTFYPGP-GCDSLCHCQEGGLVSCESSSCGPH 1232
GE C P+ +C + Y P G P P CD L HC + C+ P
Sbjct: 3296 AQGEVCQALPCPVTNCTAIEGAEYSPCGP---PCPRSCDDLVHC----VWRCQPGCYCPP 3348
Query: 1233 EACQPSGGSLGCVAVGSSTC 1252
S G++ CV G +C
Sbjct: 3349 GQVLSSNGAI-CVQPGHCSC 3367
Score = 41.6 bits (96), Expect = 0.022
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 1950 CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 2009
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
Query: 2010 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 2047
G + GS CS W C G S C PA
Sbjct: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
Query: 2048 CGLGEVCGLLPS 2059
C C PS
Sbjct: 3204 CHRHRFCARSPS 3215
Score = 41.6 bits (96), Expect = 0.022
Identities = 38/140 (27%), Positives = 53/140 (37%), Gaps = 28/140 (20%)
Query: 5123 AHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ-GVCIPVQDCGCTHNGR 5181
A +C +TC A + C++ GC C SQ G C+P C C H GR
Sbjct: 4933 APGELGLCEQTCL-EMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGR 4991
Query: 5182 -YLP-------VNSSLLTSD---CSERCS---CSSSSGLTCQAAGCPP----------GR 5217
+LP S L S C++ CS C+ + + C P
Sbjct: 4992 PHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCPSCRREAPEEQSP 5051
Query: 5218 VCEVKAEARNCWATRGLCVL 5237
C++ E RN T+G C L
Sbjct: 5052 SCQLLTELRN--FTKGTCYL 5069
Score = 41.2 bits (95), Expect = 0.028
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 3151 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 3210
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
Query: 3211 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 3248
G + GS CS W C G S C PA
Sbjct: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
Query: 3249 CGLGEVCGLLPS 3260
C C PS
Sbjct: 3204 CHRHRFCARSPS 3215
Score = 41.2 bits (95), Expect = 0.028
Identities = 37/132 (28%), Positives = 45/132 (34%), Gaps = 28/132 (21%)
Query: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC 4411
CP + + C PASC A L+ P C GC C +G +L + CVP + C C
Sbjct: 3090 CPRDKQWLDCAQG-PASC---AELSAPRGTNQTCHPGCHCPSGMLLLNNVCVPTQD-CPC 3144
Query: 4412 WANGTYHEAGSEFWAD-----------GTCSQWCRCGPGGG-----------SLVCTPAS 4449
G + GS CS W C G S C PA
Sbjct: 3145 AHEGHLYPPGSTVVRPCENCSCVSGLIANCSSW-PCAEGEPTWSPWTPWSQCSASCGPAR 3203
Query: 4450 CGLGEVCGLLPS 4461
C C PS
Sbjct: 3204 CHRHRFCARSPS 3215
Score = 41.2 bits (95), Expect = 0.028
Identities = 34/111 (30%), Positives = 43/111 (38%), Gaps = 12/111 (10%)
Query: 5117 CPL-HCPA--HSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVCIPV 5171
CP+ +C A + YS C C SC L C RC GC C +LS +C+
Sbjct: 3306 CPVTNCTAIEGAEYSPCGPPCPRSC---DDLVHCVWRCQPGCYCPPGQVLSSNGAICVQP 3362
Query: 5172 QDCGCTH--NGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCP-PGRVC 5219
C C G+ + L D C+C L C CP PG C
Sbjct: 3363 GHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGR-LNCTDLPCPVPGGWC 3412
Score = 40.8 bits (94), Expect = 0.037
Identities = 66/269 (24%), Positives = 87/269 (32%), Gaps = 72/269 (26%)
Query: 4259 CRGSCP-TCPEDR--LEQYEGPGFCGPLSSGTGGPFTTCH--AHVPPESFFKGCVL--DV 4311
C G P CP D+ L+ +GP C LS+ G TCH H P G +L +V
Sbjct: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELSAPRGTN-QTCHPGCHCP-----SGMLLLNNV 3135
Query: 4312 CMGGGDRDIL------------------CKALASYVAACQA-----AGVVIEDWRAQVGC 4348
C+ D C ++ +A C + W C
Sbjct: 3136 CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQC 3195
Query: 4349 EITC-PENSHYEVCGPPCPASCPS-----PAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 4402
+C P H P++ PS P P T +C GP E C + DR
Sbjct: 3196 SASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC---LLQGCDRA 3252
Query: 4403 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT-PASCGLG-------- 4453
G G W ++ CS+ C G + C P GLG
Sbjct: 3253 ----GGWGPWGPWSH------------CSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRA 3296
Query: 4454 --EVCGLLPSGQHGCQPVSTAECQAWGDP 4480
EVC LP C + AE G P
Sbjct: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
Score = 40.4 bits (93), Expect = 0.048
Identities = 53/203 (26%), Positives = 66/203 (32%), Gaps = 50/203 (24%)
Query: 1071 PKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEE 1130
P GP+ C L R C R P + G C T + CQ +
Sbjct: 3477 PWGPWSPCDMCLGQSHRSRAC--SRPPTP-EGGRPCPGNHTQSRPCQ---------ENST 3524
Query: 1131 LCPLSCPPHSHYEACSYGCPLSCGDLPV-----PGGCGSECHEGCVCDEGFALSGESCLP 1185
C C C CP SC DL PG G C C C G C+P
Sbjct: 3525 QCT-DCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVG--CQPTCGCPLGQLSQDGLCVP 3581
Query: 1186 LASCGCVHQ--------------GTYHPPGQTFYPGP----GCDSLCHCQEGGLVSCES- 1226
A C C +Q G+ ++ PG CD+ C C G++ C+
Sbjct: 3582 PAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDN-CTC-VAGILQCQEV 3639
Query: 1227 ---------SSCGPHEACQPSGG 1240
SS GP E C S G
Sbjct: 3640 PDCPDPGVWSSWGPWEDCSVSCG 3662
Score = 40.0 bits (92), Expect = 0.063
Identities = 60/231 (25%), Positives = 79/231 (34%), Gaps = 52/231 (22%)
Query: 4634 WQVGGAQGC---GECVSKPCPSPCTPEQQESFGGPDACGVIS--ATDGPLA----PCHGL 4684
W G ++ C G V + CP P E Q AC V +T P + PC G
Sbjct: 1713 WGQGRSRRCSPLGLLVLQNCPGP---EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGT 1769
Query: 4685 VPPAQYFQGCLLDACQVQGHPGGL--------CPAVATYVAACQAAGAQLGEWRRPDFCP 4736
+ + PGGL CP A C +G + + P CP
Sbjct: 1770 MTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATC--SGELMFQPCAP--CP 1825
Query: 4737 LQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCGCL 4795
L C S C P P GC C G VL + CV QC CL
Sbjct: 1826 LTCDDISGQVTCPPDWPCGSP--------------GCWCPEGQVLGSEGWCVWPRQCPCL 1871
Query: 4796 HDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEG--AACGPHEECRLEDG 4844
DG Y +PG + C+ CQ+G C + +C ++ G
Sbjct: 1872 VDGARY------WPGQRIKADCQL-----CICQDGRPRRCRLNPDCAVDCG 1911
Score = 40.0 bits (92), Expect = 0.063
Identities = 65/269 (24%), Positives = 87/269 (32%), Gaps = 72/269 (26%)
Query: 1857 CRGSCP-TCPEDR--LEQYEGPGFCGPLAPGTGGPFTTCH--AHVPPESFFKGCVL--DV 1909
C G P CP D+ L+ +GP C L+ G TCH H P G +L +V
Sbjct: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELS-APRGTNQTCHPGCHCP-----SGMLLLNNV 3135
Query: 1910 CMGGGDRDIL------------------CKALASYVAACQA-----AGVVIEDWRAQVGC 1946
C+ D C ++ +A C + W C
Sbjct: 3136 CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQC 3195
Query: 1947 EITC-PENSHYEVCGSPCPASCPS-----PAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 2000
+C P H + P++ PS P P T +C GP E C + DR
Sbjct: 3196 SASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC---LLQGCDRA 3252
Query: 2001 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT-PASCGLG-------- 2051
G G W ++ CS+ C G + C P GLG
Sbjct: 3253 ----GGWGPWGPWSH------------CSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRA 3296
Query: 2052 --EVCGLLPSGQHGCQPVSTAECQAWGDP 2078
EVC LP C + AE G P
Sbjct: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
Score = 40.0 bits (92), Expect = 0.063
Identities = 30/100 (30%), Positives = 34/100 (34%), Gaps = 10/100 (10%)
Query: 5121 CPAHSHYSICTRTCQGSCAALSGLTGCTTR--CFEGCECDDRFLLSQGVCIPVQDCGCTH 5178
C + C C G CA C C GC C L G CIP ++C C H
Sbjct: 4423 CTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGGCIPPEECNCWH 4482
Query: 5179 N-----GRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGC 5213
G L L C E C C L C + GC
Sbjct: 4483 TSAAGAGMTLAPGDRLQLG-CKE-CECRRGE-LHCTSQGC 4519
Score = 39.7 bits (91), Expect = 0.082
Identities = 62/249 (24%), Positives = 83/249 (33%), Gaps = 46/249 (18%)
Query: 1831 GTLAPSIPIWG-GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA------- 1882
G + PS G G+W W P W C +C + R + C PL
Sbjct: 1683 GQVGPSPEEQGCGAWGP--WSP--WGPCSRTCGPWGQGRSRR------CSPLGLLVLQNC 1732
Query: 1883 PGTGGPFTTCHAHVPPE-------SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGV 1935
PG C P S + C + C G R C + + C A
Sbjct: 1733 PGPEHQSQACFTAACPVDGEWSTWSPWSVCS-EPCRGTMTRQRQCHSPQNGGRTCAALPG 1791
Query: 1936 VIEDWRA-----QVGC-EITCPENSHYEVCGSPCPASCPS-PAPLTTPAVCEGPCVE-GC 1987
+ R Q GC TC ++ C +PCP +C +T P + PC GC
Sbjct: 1792 GLHSTRQTKPCPQDGCPNATCSGELMFQPC-APCPLTCDDISGQVTCPP--DWPCGSPGC 1848
Query: 1988 QCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 2047
C G VL ++ C C +G + G AD Q C C G P
Sbjct: 1849 WCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------RPRR 1899
Query: 2048 CGLGEVCGL 2056
C L C +
Sbjct: 1900 CRLNPDCAV 1908
Score = 39.7 bits (91), Expect = 0.082
Identities = 62/253 (24%), Positives = 81/253 (32%), Gaps = 54/253 (21%)
Query: 4233 GTLAPSIPIWG-GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLS----SGT 4287
G + PS G G+W W P W C +C + R + C PL
Sbjct: 1683 GQVGPSPEEQGCGAWGP--WSP--WGPCSRTCGPWGQGRSRR------CSPLGLLVLQNC 1732
Query: 4288 GGPFTTCHAHVPPESFFKGCVLD--------------VCMGGGDRDILCKALASYVAACQ 4333
GP H F C +D C G R C + + C
Sbjct: 1733 PGP-----EHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTCA 1787
Query: 4334 AAGVVIEDWRA-----QVGC-EITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEGPCV 4386
A + R Q GC TC ++ C P CP +C +T P + PC
Sbjct: 1788 ALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPP--DWPCG 1844
Query: 4387 E-GCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 4445
GC C G VL ++ C C +G + G AD Q C C G
Sbjct: 1845 SPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------ 1895
Query: 4446 TPASCGLGEVCGL 4458
P C L C +
Sbjct: 1896 RPRRCRLNPDCAV 1908
Score = 39.3 bits (90), Expect = 0.11
Identities = 62/249 (24%), Positives = 82/249 (32%), Gaps = 46/249 (18%)
Query: 3032 GTLAPSIPIWG-GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLA------- 3083
G + PS G G+W W P W C +C + R + C PL
Sbjct: 1683 GQVGPSPEEQGCGAWGP--WSP--WGPCSRTCGPWGQGRSRR------CSPLGLLVLQNC 1732
Query: 3084 PGTGGPFTTCHAHVPPE-------SFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGV 3136
PG C P S + C + C G R C + + C A
Sbjct: 1733 PGPEHQSQACFTAACPVDGEWSTWSPWSVCS-EPCRGTMTRQRQCHSPQNGGRTCAALPG 1791
Query: 3137 VIEDWRA-----QVGC-EITCPENSHYEVCGPPCPASCPS-PAPLTTPAVCEGPCVE-GC 3188
+ R Q GC TC ++ C P CP +C +T P + PC GC
Sbjct: 1792 GLHSTRQTKPCPQDGCPNATCSGELMFQPCAP-CPLTCDDISGQVTCPP--DWPCGSPGC 1848
Query: 3189 QCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPAS 3248
C G VL ++ C C +G + G AD Q C C G P
Sbjct: 1849 WCPEGQVLGSEGWCVWPRQCPCLVDGARYWPGQRIKAD---CQLCICQDG------RPRR 1899
Query: 3249 CGLGEVCGL 3257
C L C +
Sbjct: 1900 CRLNPDCAV 1908
Score = 39.3 bits (90), Expect = 0.11
Identities = 65/269 (24%), Positives = 86/269 (31%), Gaps = 72/269 (26%)
Query: 3058 CRGSCP-TCPEDR--LEQYEGPGFCGPLAPGTGGPFTTCH--AHVPPESFFKGCVL--DV 3110
C G P CP D+ L+ +GP C L+ G TCH H P G +L +V
Sbjct: 3082 CAGPVPGMCPRDKQWLDCAQGPASCAELS-APRGTNQTCHPGCHCP-----SGMLLLNNV 3135
Query: 3111 CMGGGDRDIL------------------CKALASYVAACQA-----AGVVIEDWRAQVGC 3147
C+ D C ++ +A C + W C
Sbjct: 3136 CVPTQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEGEPTWSPWTPWSQC 3195
Query: 3148 EITC-PENSHYEVCGPPCPASCPS-----PAPLTTPAVCEGPCVEGCQCDAGFVLSADRC 3201
+C P H P++ PS P P T +C GP E C + DR
Sbjct: 3196 SASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPC---LLQGCDRA 3252
Query: 3202 VPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT-PASCGLG-------- 3252
G G W ++ CS+ C G + C P GLG
Sbjct: 3253 ----GGWGPWGPWSH------------CSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRA 3296
Query: 3253 --EVCGLLPSGQHGCQPVSTAECQAWGDP 3279
EVC LP C + AE G P
Sbjct: 3297 QGEVCQALPCPVTNCTAIEGAEYSPCGPP 3325
Score = 38.9 bits (89), Expect = 0.14
Identities = 29/101 (28%), Positives = 33/101 (32%), Gaps = 15/101 (14%)
Query: 1145 CSYGCPLSCGDLPVPGGCGSECHEGCVCDEG-FALSGESCLPLASCGCVHQGTYHPPGQT 1203
C C L C S GCVC G F C+P C C H G H PG
Sbjct: 4940 CEQTC-LEMNATKTQSNCSSARASGCVCQPGHFRSQAGPCVPEDHCECWHLGRPHLPGSE 4998
Query: 1204 FYPG----------PGCDSLCH---CQEGGLVSCESSSCGP 1231
+ P C C C +G + E SC P
Sbjct: 4999 WQEACESCLCLSGRPVCTQHCSPLTCAQGEEMVLEPGSCCP 5039
Score = 37.4 bits (85), Expect = 0.41
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 27/124 (21%)
Query: 5058 GPFATCQAVLSPSEYFR--QCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDS 5115
GP+ C E R +C C ++ C T C+ AG
Sbjct: 3652 GPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCS-----TQVCREAG---------- 3696
Query: 5116 FCPLHCPAHSHYSICT--RTCQGSCAALSGLTGCTTR-CFEGCECDDRFLLSQGVCIPVQ 5172
CPA Y C C SCA ++ GC + C EGC C + + C VQ
Sbjct: 3697 -----CPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQ 3749
Query: 5173 DCGC 5176
+C C
Sbjct: 3750 ECPC 3753
Score = 34.7 bits (78), Expect = 2.6
Identities = 36/150 (24%), Positives = 46/150 (30%), Gaps = 33/150 (22%)
Query: 1858 RGSCP---TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 1914
R +CP TCP D G GP GP++ C D+C+G
Sbjct: 3460 REACPSYATCPVD--------GAWGPW-----GPWSPC---------------DMCLGQS 3491
Query: 1915 DRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCGSPCPASCPSPAP 1972
R C + G + Q C CG PCP SC +P
Sbjct: 3492 HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 1973 LTTPAVCEGPCVEGCQCDAGFVLSADRCVP 2002
+ C C C G + CVP
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
Score = 34.3 bits (77), Expect = 3.4
Identities = 36/150 (24%), Positives = 46/150 (30%), Gaps = 33/150 (22%)
Query: 3059 RGSCP---TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 3115
R +CP TCP D G GP GP++ C D+C+G
Sbjct: 3460 REACPSYATCPVD--------GAWGPW-----GPWSPC---------------DMCLGQS 3491
Query: 3116 DRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCGPPCPASCPSPAP 3173
R C + G + Q C CG PCP SC +P
Sbjct: 3492 HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 3174 LTTPAVCEGPCVEGCQCDAGFVLSADRCVP 3203
+ C C C G + CVP
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
Score = 34.3 bits (77), Expect = 3.4
Identities = 36/150 (24%), Positives = 46/150 (30%), Gaps = 33/150 (22%)
Query: 4260 RGSCP---TCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGG 4316
R +CP TCP D G GP GP++ C D+C+G
Sbjct: 3460 REACPSYATCPVD--------GAWGPW-----GPWSPC---------------DMCLGQS 3491
Query: 4317 DRDILCKALASYVAACQAAGVVIEDWRAQVGCE--ITCPENSHYEVCGPPCPASCPSPAP 4374
R C + G + Q C CG PCP SC +P
Sbjct: 3492 HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQPCPRSCQDLSP 3551
Query: 4375 LTTPAVCEGPCVEGCQCDAGFVLSADRCVP 4404
+ C C C G + CVP
Sbjct: 3552 GSVCQPGSVGCQPTCGCPLGQLSQDGLCVP 3581
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 380 bits (976), Expect = e-104
Identities = 345/1282 (26%), Positives = 489/1282 (38%), Gaps = 200/1282 (15%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C G +FDG + F G C+YLL G C + + F ++ + + + VS + +
Sbjct: 35 CSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSII--GDFQNGKRVSLSVYL 88
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
G + G V D +P+ A+ G G + +G D
Sbjct: 89 -----GEFFDIHLFVNGTVTQGDQRVSMPY-ASKGLYLETEAGYYKLSGEAYGFVARIDG 142
Query: 984 NARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEET-RPGCGA 1042
+ + Y CGLCGNFN DD + G ++ F NSW + C
Sbjct: 143 SGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCER 202
Query: 1043 TEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQS 1102
P S Q +C +L F CH +DP+ V C C G
Sbjct: 203 ASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLCECAGGL 261
Query: 1103 GPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1162
C AL YA C G ++ W C CP Y C C +C L + C
Sbjct: 262 ECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEMC 321
Query: 1163 GSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1222
C +GC C EG L C+ C CVH G +PPG + C++ C C+ +
Sbjct: 322 QERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT-CICRNSQWI 378
Query: 1223 SCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTC 1282
C + C P E C +G H+ +FD R F F G C Y+LA+ C
Sbjct: 379 -CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSGICQYLLARDC 418
Query: 1283 GTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVA---NFTLRLEQRQWKVTVNGVDMKL 1338
H F+++ E V + R +V TR +TV++ N ++L+ V ++G D++L
Sbjct: 419 QD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG-VAMDGQDVQL 473
Query: 1339 PVVLANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGD 1396
P L G +R QH + +G L++ +D + V + Y + CGLCGNYNG+
Sbjct: 474 P--LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGN 530
Query: 1397 PKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQ 1456
DDF P+G +FGN+W+ C +D H P L +
Sbjct: 531 QGDDFLTPSGLAEPRVEDFGNAWKL---HGDC----------QDLQKQHSDPCALNPRMT 577
Query: 1457 K--EEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQA 1514
+ EE C +L+SPT +CH+ V P L++C +D+C LC + +Y +AC
Sbjct: 578 RFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
Query: 1515 AGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQ-CQDGCAEGCQCDSGFL 1573
G V WR C + CP Y C C+L C +LS P + C + C EGC C G
Sbjct: 636 RGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
Query: 1574 YNGQA-CVPIQQCGCY---------------HNGVYYE---------------------- 1595
+ + CVP QC CY H Y E
Sbjct: 695 MDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLPDAVLS 754
Query: 1596 --------------PEQTVLI---DNCRQQ---CT--CHAGKGMVCQEHSCKPGQVCQPS 1633
P L+ DN R + CT C + C C G +C P
Sbjct: 755 SPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQ-NYDLECMSMGCVSGCLCPP- 812
Query: 1634 GGILS----CVTKDPC----HGVTCRPQETCKEQGGQGVCLPNY--------EATCWLWG 1677
G++ CV + C G P ET K VC +ATC G
Sbjct: 813 -GMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCDATCSTIG 871
Query: 1678 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP--FTVTTKNQNRGNPAVSYVRVV 1735
HY +FDG K+ F G C YVL C G P F + N+ +P+V + V
Sbjct: 872 MAHYLTFDGLKYLFPGECQYVLVQDYC------GSNPGTFRILVGNKGCSHPSVKCKKRV 925
Query: 1736 TVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDW 1795
T+ G I + E+ R P+ + V + +L+ L V +D
Sbjct: 926 TILVEGGEIELFDGEVNVKR--------PMK-DETHFEVVESGRYIILLLGKALSVVWDR 976
Query: 1796 NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWD 1855
+ + V L +Y VCGLCGN D NND N + +G SW+ C D
Sbjct: 977 HLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV---SSQCAD 1033
Query: 1856 ECR----GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM 1911
+ S TC + ++Q C L T F C+ V PE + C+ D C
Sbjct: 1034 TRKVPLDSSPATCHNNIMKQTMVDSSCRIL---TSDVFQDCNKLVDPEPYLDVCIYDTCS 1090
Query: 1912 --GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS----------HYEVC 1959
GD C +A+Y C G V+ WR C +C E + Y C
Sbjct: 1091 CESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYECEWRYNSC 1149
Query: 1960 GSPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLS--ADRCVPLNNGCGCWANGTY 2015
C +C P PL P CVEGC C G +L CV + C G
Sbjct: 1150 APACQVTCQHPEPLACPV----QCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRR 1205
Query: 2016 HEAGSEFW---ADGTCSQWCRC 2034
+G + +D Q C C
Sbjct: 1206 FASGKKVTLNPSDPEHCQICHC 1227
Score = 375 bits (962), Expect = e-103
Identities = 347/1289 (26%), Positives = 494/1289 (38%), Gaps = 213/1289 (16%)
Query: 2068 STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 2127
STA C +G T DG ++F G C YLL+ C +F++ + + G +
Sbjct: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
Query: 2128 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VTLPFQLDSLLHAHLSGADVVVTT 2181
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
Query: 2182 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 2233
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
Query: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 2293
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
Query: 2294 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 2353
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
Query: 2354 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 2413
C SL E C+ C +GC C G +L CV +C C+H + YP G + C++
Sbjct: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT 369
Query: 2414 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMG 2473
C CR + C C P E C +G H+ +FD R F F G
Sbjct: 370 -CICRNSQWI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSG 408
Query: 2474 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVA---NFTLRLEQRQWK 2529
C Y+LA+ C H F+++ E V + R +V TR +TV++ N ++L+
Sbjct: 409 ICQYLLARDCQD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG- 463
Query: 2530 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQLM 2587
V ++G D++LP L G +R QH + +G L++ +D + V + Y
Sbjct: 464 VAMDGQDVQLP--LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
Query: 2588 CGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEE 2647
CGLCGNYNG+ DDF P+G +FGN+W+ + D L P
Sbjct: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWK-LHGDCQDLQKQHSDP---------- 569
Query: 2648 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 2707
C EE C +L+SPT +CH+ V P L++C +D+C LC +
Sbjct: 570 CALNPRMTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALA 627
Query: 2708 AYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAP-LQCPDGCAEG 2766
+Y +AC G +V WR C + CP+ Y C C+L C +LS P +C + C EG
Sbjct: 628 SYAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEG 686
Query: 2767 CQCDSGFLYNGQA-CVPIQQCGC---------------YHNGAYYE-------------- 2796
C C G + + CVP QC C +H Y E
Sbjct: 687 CFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGS 746
Query: 2797 ----------------------PEQTVLI---DNCRQQ---CTCHVGKV-VVCQEHSCKP 2827
P L+ DN R + CT + C C
Sbjct: 747 LLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVS 806
Query: 2828 GQVCQPSGGILS----CVNKDPC----HGVTCRPQETCKEQGGQGVCLPNY--------E 2871
G +C P G++ CV + C G P ET K VC +
Sbjct: 807 GCLCPP--GMVRHENRCVALERCPCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTDHVCD 864
Query: 2872 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP--FTVTTKNQNRGNPA 2929
ATC G HY +FDG K+ F G C YVL C G P F + N+ +P+
Sbjct: 865 ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYC------GSNPGTFRILVGNKGCSHPS 918
Query: 2930 VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFG 2989
V + VT+ G I + E+ R P+ + V + +L+
Sbjct: 919 VKCKKRVTILVEGGEIELFDGEVNVKR--------PMK-DETHFEVVESGRYIILLLGKA 969
Query: 2990 LQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG 3049
L V +D + + V L +Y VCGLCGN D NND N + +G SW+
Sbjct: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
Query: 3050 WDPLCWDECR----GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKG 3105
C D + S TC + ++Q C L T F C+ V PE +
Sbjct: 1028 -SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL---TSDVFQDCNKLVDPEPYLDV 1083
Query: 3106 CVLDVCM--GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------- 3155
C+ D C GD C +A+Y C G V+ WR C +C E +
Sbjct: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYEC 1142
Query: 3156 --HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLS--ADRCVPLNNGCG 3209
Y C P C +C P PL P CVEGC C G +L CV +
Sbjct: 1143 EWRYNSCAPACQVTCQHPEPLACPV----QCVEGCHAHCPPGKILDELLQTCVDPEDCPV 1198
Query: 3210 CWANGTYHEAGSEFW---ADGTCSQWCRC 3235
C G +G + +D Q C C
Sbjct: 1199 CEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
Score = 314 bits (805), Expect = 1e-84
Identities = 231/790 (29%), Positives = 325/790 (41%), Gaps = 90/790 (11%)
Query: 446 GMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSED 505
G CA G R + STA C G TFDG Y G CSY + C +
Sbjct: 19 GTLCAEGTRGR----------SSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR 68
Query: 506 DTLPAFSV--EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSL 563
+FS+ + +N R S V + + + ++T+G+ QR +P +
Sbjct: 69 ----SFSIIGDFQNGKRVSLSVYLGEFFDIHLFVNG-TVTQGD--------QRVSMPYA- 114
Query: 564 SEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
S+G ++G + +G V D + L R+ ++ CGLCGN+N DDF+
Sbjct: 115 SKGLYLETEAGYYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFM 174
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
T +G L D +FA+SW L G+ CE + +C + +G L K
Sbjct: 175 TQEGTLTSDPYDFANSWALSSGEQWCERASPPSS-SCNISSGEMQKGLWEQCQLLKSTSV 233
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
FA CH +DP PF+ C LC G C L YA+ C + G+ + W + C
Sbjct: 234 FARCHPLVDPEPFVALCEKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSP 293
Query: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTF 803
CPA Y C C +C C R CV+GC C G + G CV ++ C C
Sbjct: 294 VCPAGMEYRQCVSPCARTCQSLHINEMCQER-CVDGCSCPEGQLLDEGLCVESTECPCVH 352
Query: 804 QGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGT 863
G + PG + D CN CR+ Q + E C G
Sbjct: 353 SGKRYPPGTSLSRD--------CN----TCICRNSQWICSNEECP-------------GE 387
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVEN-EHRGSQTVSYTRA 922
C +G H+ SFD R F F G C YLL C + +F +++E + + TR+
Sbjct: 388 CLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDH----SFSIVIETVQCADDRDAVCTRS 443
Query: 923 VRVEARGV-KVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTY 981
V V G+ V+ ++ V +D LP D ++Q A VR +G +
Sbjct: 444 VTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQ---HTVTASVRLSYGEDLQM 500
Query: 982 DWN--ARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG 1039
DW+ R+ K+ YA CGLCGN+NG+ DD G FGN+W+
Sbjct: 501 DWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLH---- 556
Query: 1040 CGATEPGDCPKLDSLVAQQLQ--------SKNECGILADPKGPFRECHSKLDPQGAVRDC 1091
GDC L + S+ C +L P F CH + P +R+C
Sbjct: 557 ------GDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSP--TFEACHRAVSPLPYLRNC 608
Query: 1092 VYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPL 1151
YD C LC ALA+YAAAC G V WR C L+CP Y C C L
Sbjct: 609 RYDVCSCSDGRECLCGALASYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNL 667
Query: 1152 SCGDLPVPG-GCGSECHEGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPG 1209
+C L P C C EGC C G + C+P A C C + G P F
Sbjct: 668 TCRSLSYPDEECNEACLEGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIF---SD 724
Query: 1210 CDSLCHCQEG 1219
++C+C++G
Sbjct: 725 HHTMCYCEDG 734
Score = 308 bits (788), Expect = 1e-82
Identities = 277/1047 (26%), Positives = 389/1047 (37%), Gaps = 205/1047 (19%)
Query: 4470 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 4529
STA C +G T DG + F G C YLL+ C +F++ + + G +
Sbjct: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
Query: 4530 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VALPFQLDSLLHAHLSGADVVVTT 4583
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
Query: 4584 TSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 4635
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
Query: 4636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 4695
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
Query: 4696 LDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVS 4755
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
Query: 4756 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECER 4815
C SL E C+ C +GC C G +L CV +C C+H G+ YP PG R
Sbjct: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYP------PGTSLSR 365
Query: 4816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLH 4875
C C+ +EEC G CL G H+ + D R +
Sbjct: 366 DCNT-----CICRNSQWICSNEECP-------------GECLVTGQSHFKSFDNRYFTFS 407
Query: 4876 GSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVT---------VAGQVVSLAQGQQ 4926
G C Y+LA+ C D FSIV+E D + + T + +V L G
Sbjct: 408 GICQYLLARDCQ----DHSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAG 463
Query: 4927 VTVDGEAVALPVAVGRVR----VTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRL 4982
V +DG+ V LP+ G +R VTA R L + L++ +DG LL+ + + G+
Sbjct: 464 VAMDGQDVQLPLLKGDLRIQHTVTASVR---LSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
Query: 4983 CGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETA 5042
CGLCGN+NGN DDF+ P+G A VE FG AW+ G + + Q C
Sbjct: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQK----QHSDPCALNPRM 576
Query: 5043 PYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQ 5102
S EAC L +P F C +SP Y R C YD+C+ + LC +LA+Y AAC
Sbjct: 577 TRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACA 634
Query: 5103 AAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG-CTTRCFEGCECDDRF 5161
GV V WR C L+CP Y C C +C +LS C C EGC C
Sbjct: 635 GRGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGL 693
Query: 5162 LLSQ-GVCIPVQDCGCTHN--------------------------------GRYLPVNSS 5188
+ + G C+P C C ++ G LP +
Sbjct: 694 YMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTMCYCEDGFMHCTMSGVPGSLLP--DA 751
Query: 5189 LLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWAT---RGLCVLSVGANLTT 5245
+L+S S R S S CP + +AE C T L +S+G
Sbjct: 752 VLSSPLSHRSKRSLSCRPPMVKLVCPADNL---RAEGLECTKTCQNYDLECMSMGC---- 804
Query: 5246 FDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEV------------------------ 5281
G PG+ +RC L+ P + E
Sbjct: 805 ---VSGCLCPPGMVRHENRCVALERC-PCFHQGKEYAPGETVKIGCNTCVCRDRKWNCTD 860
Query: 5282 QICHGKTEAVGQVHIFFQDGMVTLTP------------------------NKG------- 5310
+C +G H DG+ L P NKG
Sbjct: 861 HVCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPGTFRILVGNKGCSHPSVK 920
Query: 5311 ------VWVNGLRVDL---------PAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGK 5355
+ V G ++L P + V + +L+ KA VW +
Sbjct: 921 CKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESGRYIILLLGKALSVVW-DRHLS 979
Query: 5356 VAVIVSNDHAGKLCGACGNFDGDQTND 5382
++V++ + K+CG CGNFDG Q ND
Sbjct: 980 ISVVLKQTYQEKVCGLCGNFDGIQNND 1006
Score = 286 bits (733), Expect = 3e-76
Identities = 227/808 (28%), Positives = 336/808 (41%), Gaps = 91/808 (11%)
Query: 3269 STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVS 3328
STA C +G T DG + F G C YLL+ C +F++ + + G +
Sbjct: 31 STARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQ-----KRSFSI-IGDFQNGKR--- 81
Query: 3329 YTRSVTLQIYNHSLTLSARWPRKLQVDGVF------VTLPFQLDSLLHAHLSGADVVVTT 3382
V+L +Y L + L V+G V++P+ L +G +
Sbjct: 82 ----VSLSVY-----LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGE 132
Query: 3383 TSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQ 3434
G DG ++ + Y CGLCGN+N DD G W
Sbjct: 133 AYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWA 192
Query: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 3494
+ + E S P S + G + C ++ +T A CH LV P + C
Sbjct: 193 LSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCE 251
Query: 3495 LDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGS 3554
C+ G CPA+ Y C G L W C CPA Y C C +
Sbjct: 252 KTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCART 311
Query: 3555 CPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 3614
C SL E C+ C +GC C G +L CV +C C+H + YP G + C++
Sbjct: 312 CQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTSL--SRDCNT 369
Query: 3615 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMG 3674
C CR + C C P E C +G H+ +FD F F G
Sbjct: 370 -CICRNSQWI-CSNEEC-PGE------------------CLVTGQSHFKSFDNRYFTFSG 408
Query: 3675 TCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV-TRVITVQVA---NFTLRLEQRQWK 3730
C Y+LA+ C H F+++ E V + R +V TR +TV++ N ++L+
Sbjct: 409 ICQYLLARDCQD----HSFSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGA-G 463
Query: 3731 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFG--LRVAYDLVYYVRVTVPGNYYQLM 3788
V ++G D++LP L G +R QH + +G L++ +D + V + Y
Sbjct: 464 VAMDGQDVQLP--LLKGDLRI-QHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKT 520
Query: 3789 CGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDK 3848
CGLCGNYNG+ DDF P+G +FGN+W ++ D L SD
Sbjct: 521 CGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAW-KLHGDCQDLQKQ----------HSDP 569
Query: 3849 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 3908
C EE C +L+SPT +CH+ V P L++C +D+C LC +
Sbjct: 570 CALNPRMTRFSEEACAVLTSPT--FEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALA 627
Query: 3909 AYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAP-LQCPDGCAEG 3967
+Y +AC G V WR C + CP+ Y C C+L C +LS P +C + C EG
Sbjct: 628 SYAAACAGRGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEG 686
Query: 3968 CQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC 4026
C C G + + CVP QC CY++G ++PE + + C C G + S
Sbjct: 687 CFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPED--IFSDHHTMCYCEDGFMHCTM--SG 742
Query: 4027 KPGQVCQPSGGILSCVTKDPCHGVTCRP 4054
PG + P + S ++ ++CRP
Sbjct: 743 VPGSLL-PDAVLSSPLSHRSKRSLSCRP 769
Score = 278 bits (711), Expect = 1e-73
Identities = 220/764 (28%), Positives = 302/764 (39%), Gaps = 76/764 (9%)
Query: 4073 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 4132
A C L+G ++FDG + F G C+Y+LA GC S F++ QN ++S
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
Query: 4133 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 4192
LG IH G V ++P + + G K L +G
Sbjct: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYK-LSGEAYGFV 137
Query: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 4252
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
Query: 4253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVC 4312
C + +C E +G L T F CH V PE F C +C
Sbjct: 198 QWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLC 255
Query: 4313 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSP 4372
G + C AL Y C G+V+ W C CP Y C PC +C S
Sbjct: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQS- 314
Query: 4373 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTC- 4430
L +C+ CV+GC C G +L CV + C C +G + G+ D TC
Sbjct: 315 --LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYPPGTSLSRDCNTCI 371
Query: 4431 ---SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 4487
SQW +C+ C EC G H+ + D
Sbjct: 372 CRNSQW----------ICSNEEC--------------------PGECLVTGQSHFKSFDN 401
Query: 4488 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN-HSLTLS 4546
F F G C+YLL+ C TV A++ AV TRSVT+++ H+ +
Sbjct: 402 RYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSVTVRLPGLHNSLVK 457
Query: 4547 ARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 4606
+ + +DG V LP L H A V ++ L + +DG + +++ YA
Sbjct: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
Query: 4607 ASLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSKPCPSPCTPEQQES 4661
CGLCGNYN + DD G +P G A G+C + K PC + +
Sbjct: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
Query: 4662 FGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQA 4721
+AC V+ T CH V P Y + C D C LC A+A+Y AAC
Sbjct: 578 RFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
Query: 4722 AGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP-EGCESACREGCVCDAGFV 4780
G ++ WR P C L CP Y CG C ++C SLS P E C AC EGC C G
Sbjct: 636 RGVRVA-WREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
Query: 4781 LS--GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG 4822
+ GD CVP QC C +DG + ++F + C C G
Sbjct: 695 MDERGD-CVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCEDG 734
Score = 278 bits (710), Expect = 1e-73
Identities = 220/764 (28%), Positives = 302/764 (39%), Gaps = 76/764 (9%)
Query: 1671 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 1730
A C L+G ++FDG + F G C+Y+LA GC S F++ QN ++S
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
Query: 1731 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 1790
LG IH G V ++P + + G T+ L +G
Sbjct: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYA-SKGLYLETEAGYYKLSGEAYGFV 137
Query: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
Query: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 1910
C + +C E +G L T F CH V PE F C +C
Sbjct: 198 QWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLC 255
Query: 1911 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSP 1970
G + C AL Y C G+V+ W C CP Y C SPC +C S
Sbjct: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQS- 314
Query: 1971 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTC- 2028
L +C+ CV+GC C G +L CV + C C +G + G+ D TC
Sbjct: 315 --LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYPPGTSLSRDCNTCI 371
Query: 2029 ---SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 2085
SQW +C+ C EC G H+ + D
Sbjct: 372 CRNSQW----------ICSNEEC--------------------PGECLVTGQSHFKSFDN 401
Query: 2086 HRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN-HSLTLS 2144
F F G C+YLL+ C TV A++ AV TRSVT+++ H+ +
Sbjct: 402 RYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSVTVRLPGLHNSLVK 457
Query: 2145 ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 2204
+ + +DG V LP L H A V ++ L + +DG + +++ YA
Sbjct: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
Query: 2205 GSLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSKPCPSPCTPEQQES 2259
G CGLCGNYN + DD G +P G A G+C + K PC + +
Sbjct: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
Query: 2260 FGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQA 2319
+AC V+ T CH V P Y + C D C LC A+A+Y AAC
Sbjct: 578 RFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
Query: 2320 AGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAP-EGCESACREGCVCDAGFV 2378
G ++ WR P C CP Y CG C +C SLS P E C AC EGC C G
Sbjct: 636 RGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
Query: 2379 LS--GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 2420
+ GD CVP QC C +D + F ++C C +G
Sbjct: 695 MDERGD-CVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCEDG 734
Score = 275 bits (704), Expect = 7e-73
Identities = 219/764 (28%), Positives = 301/764 (39%), Gaps = 76/764 (9%)
Query: 2872 ATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVS 2931
A C L+G ++FDG + F G C+Y+LA GC S F++ QN ++S
Sbjct: 33 ARCSLFGSDFVNTFDGSMYSFAGYCSYLLAG-GCQKRS------FSIIGDFQNGKRVSLS 85
Query: 2932 YVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQ 2991
LG IH G V ++P + + G T+ L +G
Sbjct: 86 VY-------LGEFFDIHLFVNGTVTQGDQRVSMPYA-SKGLYLETEAGYYKLSGEAYGFV 137
Query: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051
D + V L Y CGLCGN + +D + GTL + SW +
Sbjct: 138 ARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGE 197
Query: 3052 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 3111
C + +C E +G L T F CH V PE F C +C
Sbjct: 198 QWC-ERASPPSSSCNISSGEMQKGLWEQCQLLKSTS-VFARCHPLVDPEPFVALCEKTLC 255
Query: 3112 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSP 3171
G + C AL Y C G+V+ W C CP Y C PC +C S
Sbjct: 256 ECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQS- 314
Query: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWAD-GTC- 3229
L +C+ CV+GC C G +L CV + C C +G + G+ D TC
Sbjct: 315 --LHINEMCQERCVDGCSCPEGQLLDEGLCVE-STECPCVHSGKRYPPGTSLSRDCNTCI 371
Query: 3230 ---SQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDG 3286
SQW +C+ C EC G H+ + D
Sbjct: 372 CRNSQW----------ICSNEEC--------------------PGECLVTGQSHFKSFDN 401
Query: 3287 HRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYN-HSLTLS 3345
F F G C+YLL+ C TV A++ AV TRSVT+++ H+ +
Sbjct: 402 RYFTFSGICQYLLARDCQDHSFSIVIETVQCADDR---DAVC-TRSVTVRLPGLHNSLVK 457
Query: 3346 ARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA 3405
+ + +DG V LP L H A V ++ L + +DG + +++ YA
Sbjct: 458 LKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYA 517
Query: 3406 GSLCGLCGNYNQDPADDLKAVGG--KPAGWQVGGAQGC-GEC--VSKPCPSPCTPEQQES 3460
G CGLCGNYN + DD G +P G A G+C + K PC + +
Sbjct: 518 GKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLHGDCQDLQKQHSDPCALNPRMT 577
Query: 3461 FGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQA 3520
+AC V+ T CH V P Y + C D C LC A+A+Y AAC
Sbjct: 578 RFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCSCSDGRECLCGALASYAAACAG 635
Query: 3521 AGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAP-EGCESACREGCVCDAGFV 3579
G ++ WR P C CP Y CG C +C SLS P E C AC EGC C G
Sbjct: 636 RGVRV-AWREPGRCELNCPKGQVYLQCGTPCNLTCRSLSYPDEECNEACLEGCFCPPGLY 694
Query: 3580 LS--GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 3621
+ GD CVP QC C +D + F ++C C +G
Sbjct: 695 MDERGD-CVPKAQCPCYYDGEIFQPEDIF---SDHHTMCYCEDG 734
Score = 270 bits (689), Expect = 4e-71
Identities = 226/793 (28%), Positives = 326/793 (41%), Gaps = 96/793 (12%)
Query: 1249 SSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVT 1308
++ C G TFDG + F G C Y+LA C R F+++ + + NG+
Sbjct: 32 TARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRS----FSIIGD---FQNGKRVSL 84
Query: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN-GQIRASQHGSDVVIETDFGLRVA 1367
V + + L + TV D ++ + A+ G ++ G + +G
Sbjct: 85 SVYLGEFFDIHLFVNG-----TVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVAR 139
Query: 1368 YDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSP 1427
D +V + Y+ + CGLCGN+N +DDF G+ + +F NSW +
Sbjct: 140 IDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199
Query: 1428 CLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDC 1487
C PP S I S E++K ++ C LL S T + CH LVDP+ + C
Sbjct: 200 C--ERASPPSSSCNISSG----EMQKGLWEQ--CQLLKS-TSVFARCHPLVDPEPFVALC 250
Query: 1488 IFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSL 1547
LC G L C + Y C G + W + C CP Y C C+
Sbjct: 251 EKTLCECAGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCAR 310
Query: 1548 GCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQ 1607
C +L CQ+ C +GC C G L + CV +C C H+G Y P T L +C
Sbjct: 311 TCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRY-PPGTSLSRDC-N 368
Query: 1608 QCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLP 1667
C C + +C C PG+
Sbjct: 369 TCICRNSQ-WICSNEEC-PGE--------------------------------------- 387
Query: 1668 NYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN-QNRGN 1726
C + G H+ SFD R F F G C Y+LA C S F++ + Q +
Sbjct: 388 -----CLVTGQSHFKSFDNRYFTFSGICQYLLA-RDCQDHS------FSIVIETVQCADD 435
Query: 1727 PAVSYVRVVTVAALGTNISIHKDEIGK-VRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
R VTV G + S+ K + G V ++G LP+ D RI T AS L
Sbjct: 436 RDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYG 495
Query: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
+ LQ+ +D R+ V L Y G CGLCGN + N +D + P+G P + +G +W+
Sbjct: 496 E-DLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWK 554
Query: 1846 APGWDPLCWD-ECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKG 1904
G C D + + S P R+ ++ C L T F CH V P + +
Sbjct: 555 LHG---DCQDLQKQHSDPCALNPRMTRFSEEA-CAVL---TSPTFEACHRAVSPLPYLRN 607
Query: 1905 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCP 1964
C DVC R+ LC ALASY AAC GV + WR CE+ CP+ Y CG+PC
Sbjct: 608 CRYDVCSCSDGRECLCGALASYAAACAGRGVRVA-WREPGRCELNCPKGQVYLQCGTPCN 666
Query: 1965 ASCPSPAPLTTP-AVCEGPCVEGCQCDAGFVL-SADRCVPLNNGCGCWANGTYHEAGSEF 2022
+C S L+ P C C+EGC C G + CVP C C+ +G + +
Sbjct: 667 LTCRS---LSYPDEECNEACLEGCFCPPGLYMDERGDCVP-KAQCPCYYDGEIFQP-EDI 721
Query: 2023 WADGTCSQWCRCG 2035
++D +C G
Sbjct: 722 FSDHHTMCYCEDG 734
Score = 178 bits (451), Expect = 1e-43
Identities = 151/530 (28%), Positives = 218/530 (41%), Gaps = 83/530 (15%)
Query: 738 PANCPLSCPA-NSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 796
P L CPA N R E G C +C C CV GC+C PG V CV
Sbjct: 769 PPMVKLVCPADNLRAE--GLECTKTCQNYDL--ECMSMGCVSGCLCPPGMVRHENRCVAL 824
Query: 797 SSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGC 856
C C QG + APG+ V + CN CRD++ C
Sbjct: 825 ERCPCFHQGKEYAPGETV--------KIGCNTCV----CRDRKWNCTDHVCDA------- 865
Query: 857 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRGSQ 915
TC G HY++FDG ++ F G C Y+LV CG N FR+LV N+
Sbjct: 866 ------TCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHP 917
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDF 975
+V + V + G ++ + + G+V V ++ + +V GR ++
Sbjct: 918 SVKCKKRVTILVEGGEIEL---FDGEVNVKRPMK------DETHFEVVESGRYIILLLGK 968
Query: 976 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQ-- 1033
L+V +D + ++ + +Y E +CGLCGNF+G +DL + + FGNSW+
Sbjct: 969 ALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVS 1028
Query: 1034 ---EETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRD 1090
+TR + P C + + +Q + C IL F++C+ +DP+ +
Sbjct: 1029 SQCADTRKVPLDSSPATC---HNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDV 1083
Query: 1091 CVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------- 1140
C+YD C G CD +A YA C G V WR+ LCP SC +
Sbjct: 1084 CIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEERNLRENGYEC 1142
Query: 1141 --HYEACSYGCPLSCGDLPVPGGCGSECHEGC--VCDEGFALSG--ESCLPLASCG-CVH 1193
Y +C+ C ++C P P C +C EGC C G L ++C+ C C
Sbjct: 1143 EWRYNSCAPACQVTC-QHPEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEV 1201
Query: 1194 QGTYHPPGQ--TFYPG-PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
G G+ T P P +CHC L EACQ GG
Sbjct: 1202 AGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC---------EACQEPGG 1242
Score = 177 bits (450), Expect = 2e-43
Identities = 154/565 (27%), Positives = 223/565 (39%), Gaps = 81/565 (14%)
Query: 2297 CQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPS 2356
C + G PG L P + L RP CPA + G C +C +
Sbjct: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
Query: 2357 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 2416
E C GC+C G V + CV + +C C H + Y G+T G C++ C
Sbjct: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
Query: 2417 CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCV 2476
CR+ +C H V TC G HY TFDG ++ F G C
Sbjct: 851 CRD------RKWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQ 890
Query: 2477 YVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGV 2535
YVL Q CG+ PG F +L N + V + +T+ V + L + V
Sbjct: 891 YVLVQDYCGSNPGT--FRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGE-------V 941
Query: 2536 DMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYN 2595
++K P+ + G +++ L V +D + V + Y + +CGLCGN++
Sbjct: 942 NVKRPMK-DETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFD 1000
Query: 2596 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKK 2655
G +D N + +FGNSW+ S C P S C + K+
Sbjct: 1001 GIQNNDLTSSNLQVEEDPVDFGNSWK---VSSQCADTRKVPLDSS----PATCHNNIMKQ 1053
Query: 2656 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSAC 2713
+ C +L+S C+KLVDP+ L CI+D C G+ + C I AY C
Sbjct: 1054 TMVDSSCRILTSDV--FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 1111
Query: 2714 QAAGGQVEPWRNETFCPMECPQNS----------HYELCADTCSLGCSALSAPLQCPDGC 2763
A G+V WR T CP C + + Y CA C + C PL CP C
Sbjct: 1112 -AQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQH-PEPLACPVQC 1169
Query: 2764 AEGC--QCDSGFLYNG--QACVPIQQCG-CYHNGAYYEPEQTVLI-----DNCRQQCTCH 2813
EGC C G + + Q CV + C C G + + V + ++C Q C C
Sbjct: 1170 VEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHC-QICHCD 1228
Query: 2814 VGKVVVCQEHSCKPGQVCQPSGGIL 2838
V + + CQ GG++
Sbjct: 1229 VVNLTC---------EACQEPGGLV 1244
Score = 177 bits (449), Expect = 3e-43
Identities = 157/577 (27%), Positives = 226/577 (39%), Gaps = 81/577 (14%)
Query: 3498 CQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPS 3557
C + G PG L P + L RP CPA + G C +C +
Sbjct: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
Query: 3558 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 3617
E C GC+C G V + CV + +C C H + Y G+T G C++ C
Sbjct: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
Query: 3618 CREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCV 3677
CR+ +C H V TC G HY TFDG ++ F G C
Sbjct: 851 CRD------RKWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQ 890
Query: 3678 YVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGV 3736
YVL Q CG+ PG F +L N + V + +T+ V + L + V
Sbjct: 891 YVLVQDYCGSNPGT--FRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGE-------V 941
Query: 3737 DMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYN 3796
++K P+ + G +++ L V +D + V + Y + +CGLCGN++
Sbjct: 942 NVKRPMK-DETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFD 1000
Query: 3797 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKK 3856
G +D N + +FGNSW+ S C P S+ C + K+
Sbjct: 1001 GIQNNDLTSSNLQVEEDPVDFGNSWK---VSSQCADTRKVPLDSSPA----TCHNNIMKQ 1053
Query: 3857 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSAC 3914
+ C +L+S C+KLVDP+ L CI+D C G+ + C I AY C
Sbjct: 1054 TMVDSSCRILTSDV--FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC 1111
Query: 3915 QAAGGHVEPWRNETFCPMECPQNS----------HYELCADTCSLGCSALSAPLQCPDGC 3964
A G V WR T CP C + + Y CA C + C PL CP C
Sbjct: 1112 -AQHGKVVTWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQH-PEPLACPVQC 1169
Query: 3965 AEGC--QCDSGFLYNG--QACVPIQQCG-CYHNGVYYEPEQTVLI-----DNCRQQCTCH 4014
EGC C G + + Q CV + C C G + + V + ++C Q C C
Sbjct: 1170 VEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHC-QICHCD 1228
Query: 4015 VGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVT 4051
V + + CQ GG++ T P T
Sbjct: 1229 VVNLTC---------EACQEPGGLVVPPTDAPVSPTT 1256
Score = 176 bits (447), Expect = 4e-43
Identities = 144/542 (26%), Positives = 216/542 (39%), Gaps = 53/542 (9%)
Query: 4855 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQR----L 4910
RC G T DG +Y G CSY+LA C + FSI+ GD Q
Sbjct: 34 RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKR----SFSII------GDFQNGKRVS 83
Query: 4911 LVTVAGQV--VSLAQGQQVTVDGEAVALPVAV-GRVRVTAEGRNMVLQTTKGLRLLFDGD 4967
L G+ + L VT + V++P A G T G + G DG
Sbjct: 84 LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARIDGS 143
Query: 4968 AHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEG 5027
+ + + + + CGLCGNFN DDF+ G+ S F +W + C
Sbjct: 144 GNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERA 203
Query: 5028 CGPQG-CPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGD 5086
P C + E E C QL FA C ++ P + C LC G
Sbjct: 204 SPPSSSCNISSGEMQKGLW--EQC-QLLKSTSVFARCHPLVDPEPFVALCEKTLCECAGG 260
Query: 5087 KAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG 5146
C +L Y C G+ + W S C CPA Y C C +C +L
Sbjct: 261 LECACPALLEYARTCAQEGMVLYGWTDHSACSPVCPAGMEYRQCVSPCARTCQSLHINEM 320
Query: 5147 CTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGL 5206
C RC +GC C + LL +G+C+ +C C H+G+ P +S L+ DC+ C C +S +
Sbjct: 321 CQERCVDGCSCPEGQLLDEGLCVESTECPCVHSGKRYPPGTS-LSRDCN-TCICRNSQWI 378
Query: 5207 TCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCP 5266
C CP G C+++ ++ +FD + Y L+ C
Sbjct: 379 -CSNEECP------------------GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQ 419
Query: 5267 GLQNTIPWYRVVAEVQICHGKTEAVGQVHIF-----FQDGMVTLTPNKGVWVNGLRVDLP 5321
+ +V E C +AV + + +V L GV ++G V LP
Sbjct: 420 DHS-----FSIVIETVQCADDRDAVCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLP 474
Query: 5322 AEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTN 5381
K + + T S+ + +Q+ G++ V +S +AGK CG CGN++G+Q +
Sbjct: 475 LLK-GDLRIQHTVTASVRLSYGEDLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGD 533
Query: 5382 DW 5383
D+
Sbjct: 534 DF 535
Score = 167 bits (423), Expect = 3e-40
Identities = 139/506 (27%), Positives = 202/506 (39%), Gaps = 75/506 (14%)
Query: 1166 CHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCE 1225
C GC+C G C+ L C C HQG + PG+T G C++ C C++
Sbjct: 804 CVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CVCRD------R 854
Query: 1226 SSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGT 1284
+C H V +TC G HY TFDG ++ F G C YVL Q CG+
Sbjct: 855 KWNCTDH--------------VCDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGS 900
Query: 1285 RPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLAN 1344
PG F +L N + V + +T+ V + L + V++K P+
Sbjct: 901 NPGT--FRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGE-------VNVKRPMK-DE 950
Query: 1345 GQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKP 1404
+ G +++ L V +D + V + Y +++CGLCGN++G +D
Sbjct: 951 THFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSS 1010
Query: 1405 NGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLL 1464
N + +FGNSW+ S C P S C + K+ + C +L
Sbjct: 1011 NLQVEEDPVDFGNSWK---VSSQCADTRKVPLDSSPA----TCHNNIMKQTMVDSSCRIL 1063
Query: 1465 SSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPW 1522
+S C+KLVDP+ L CI+D C G+ + C I AY C A G V W
Sbjct: 1064 TSDV--FQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVC-AQHGKVVTW 1120
Query: 1523 RTETFCPMECPPNS----------HYELCADTCSLGC---SALSAPPQCQDGCAEGCQCD 1569
RT T CP C + Y CA C + C L+ P QC +GC C
Sbjct: 1121 RTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPG 1180
Query: 1570 SGFLYNGQACVPIQQCG-CYHNGVYYEPEQTVLI-----DNCRQQCTCHAGKGMVCQEHS 1623
Q CV + C C G + + V + ++C Q C C + C
Sbjct: 1181 KILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHC-QICHCDV-VNLTC---- 1234
Query: 1624 CKPGQVCQPSGGILSCVTKDPCHGVT 1649
+ CQ GG++ T P T
Sbjct: 1235 ----EACQEPGGLVVPPTDAPVSPTT 1256
Score = 155 bits (393), Expect = 8e-37
Identities = 160/638 (25%), Positives = 226/638 (35%), Gaps = 124/638 (19%)
Query: 3830 CLPPPTCPPG-----SAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQG 3884
CL CPPG C+P +CP + G + P S H + +
Sbjct: 683 CLEGCFCPPGLYMDERGDCVPKAQCPCYYD---------GEIFQPEDIFSDHHTMCYCED 733
Query: 3885 PLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCA 3944
C G + S+ ++ S + P + CP + + E C
Sbjct: 734 GFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLS---CRPPMVKLVCPADNLRAEGLE-CT 789
Query: 3945 DTCSLGCSALSAPLQCPD-GCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVL 4003
TC + L+C GC GC C G + + CV +++C C+H G Y P +TV
Sbjct: 790 KTCQ------NYDLECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVK 843
Query: 4004 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGG 4063
I C C C K C +H C
Sbjct: 844 I-GCNT-CVCRDRKWN-CTDHVC------------------------------------- 863
Query: 4064 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP--FTVTT 4121
+ATC G HY +FDG K+ F G C YVL C G P F +
Sbjct: 864 --------DATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYC------GSNPGTFRILV 909
Query: 4122 KNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGAS 4181
N+ +P+V + VT+ G I + E+ R P+ + V +
Sbjct: 910 GNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKR--------PMK-DETHFEVVESGR 960
Query: 4182 KALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPI 4241
+L+ L V +D + + V L +Y VCGLCGN D NND N +
Sbjct: 961 YIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVD 1020
Query: 4242 WGGSWRAPGWDPLCWDECR----GSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAH 4297
+G SW+ C D + S TC + ++Q C L+S F C+
Sbjct: 1021 FGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDV---FQDCNKL 1074
Query: 4298 VPPESFFKGCVLDVCM--GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPEN 4355
V PE + C+ D C GD C +A+Y C G V+ WR C +C E
Sbjct: 1075 VDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVV-TWRTATLCPQSCEER 1133
Query: 4356 S----------HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGC--QCDAGFVLS--ADR 4401
+ Y C P C +C P PL P CVEGC C G +L
Sbjct: 1134 NLRENGYECEWRYNSCAPACQVTCQHPEPLACPV----QCVEGCHAHCPPGKILDELLQT 1189
Query: 4402 CVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRC 4436
CV + C G +G + +D Q C C
Sbjct: 1190 CVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC 1227
Score = 153 bits (386), Expect = 5e-36
Identities = 149/550 (27%), Positives = 210/550 (38%), Gaps = 73/550 (13%)
Query: 4699 CQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPS 4758
C + G PG L P + L RP L CPA + G C +C +
Sbjct: 738 CTMSGVPGSLLPDAVLSSPLSHRSKRSLS--CRPPMVKLVCPA-DNLRAEGLECTKTCQN 794
Query: 4759 LSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818
E C GC+C G V + CV + +C C H G+ Y GE G C C
Sbjct: 795 YDL-ECMSMGCVSGCLCPPGMVRHENRCVALERCPCFHQGKEYAPGETVKIG--CNT-CV 850
Query: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSC 4878
C C H C AT C G HY+T DG Y G C
Sbjct: 851 CR-------DRKWNCTDH----------VCDAT----CSTIGMAHYLTFDGLKYLFPGEC 889
Query: 4879 SYVLAQ-VCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV-DGEA-VA 4935
YVL Q C PG F I++ V +V L +G ++ + DGE V
Sbjct: 890 QYVLVQDYCGSNPGT--FRILVGNKGCSHPS---VKCKKRVTILVEGGEIELFDGEVNVK 944
Query: 4936 LPVA-VGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWS 4994
P+ V GR ++L K L +++D + + + ++ ++CGLCGNF+G +
Sbjct: 945 RPMKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQN 1004
Query: 4995 DDFVLPNGSAASSVETFGAAWRAPGSSKGCGE------GCGPQGCPVCLAEETAPYESNE 5048
+D N FG +W+ S C + P C + ++T +
Sbjct: 1005 NDLTSSNLQVEEDPVDFGNSWKV---SSQCADTRKVPLDSSPATCHNNIMKQTM---VDS 1058
Query: 5049 ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGV 5106
+C L + F C ++ P Y C+YD C+ + GD A C ++AAY C G
Sbjct: 1059 SCRILTS--DVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGK 1116
Query: 5107 AVKPWRTDSFCPLHCPAHS----------HYSICTRTCQGSCAALSGLTGCTTRCFEGC- 5155
V WRT + CP C + Y+ C CQ +C L C +C EGC
Sbjct: 1117 VV-TWRTATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQHPEPL-ACPVQCVEGCH 1174
Query: 5156 -ECDDRFLLSQ--GVCIPVQDCG-CTHNGRYLPVNSSL-LTSDCSERCSCSSSS--GLTC 5208
C +L + C+ +DC C GR + L E C LTC
Sbjct: 1175 AHCPPGKILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTC 1234
Query: 5209 QAAGCPPGRV 5218
+A P G V
Sbjct: 1235 EACQEPGGLV 1244
Score = 135 bits (340), Expect = 1e-30
Identities = 115/398 (28%), Positives = 169/398 (42%), Gaps = 43/398 (10%)
Query: 470 AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFSVEAKNEHRGSRRVSYV 528
A C G HY TFDG +Y G C Y +V+ C + F + N+ V
Sbjct: 865 ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPSVKCK 922
Query: 529 GLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVT 588
VT+ + L GEV + P+ E V +SG ++ L L V
Sbjct: 923 KRVTILVEGGEIELFDGEVNV--------KRPMK-DETHFEVVESGRYIILLLGKALSVV 973
Query: 589 YDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYL 648
+D +++ L +Q++VCGLCGN++G +D + + + D V+F +SWK+
Sbjct: 974 WDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKVSS---Q 1030
Query: 649 CEDGCQ---NNCPA-CTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDL 704
C D + ++ PA C + D C +LT F C+ +DP P+L+ C+YD
Sbjct: 1031 CADTRKVPLDSSPATCHNNIMKQTMVDSSCRILT--SDVFQDCNKLVDPEPYLDVCIYDT 1088
Query: 705 CVVG--GERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS----------RYE 752
C G+ C ++AYA C + G V WR+ CP SC + RY
Sbjct: 1089 CSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEWRYN 1147
Query: 753 LCGPACPTSCNGAAAPSNCSGRPCVEGC--VCLPGFVASG--GACVPASSCG-CTFQGLQ 807
C PAC +C P C + CVEGC C PG + CV C C G +
Sbjct: 1148 SCAPACQVTCQ-HPEPLACPVQ-CVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAGRR 1205
Query: 808 LAPGQEVWADELCQRRC-TCNGATHQVTCRDKQSCPAG 844
A G++V + C C+ +TC Q P G
Sbjct: 1206 FASGKKVTLNPSDPEHCQICHCDVVNLTCEACQE-PGG 1242
Score = 132 bits (332), Expect = 9e-30
Identities = 118/462 (25%), Positives = 184/462 (39%), Gaps = 60/462 (12%)
Query: 4797 DGRYYPLGEVFYPGPECERRCECGPGGH-------VTCQEGA--ACGPHEECRLEDGVQA 4847
DG G+V+ +C C P G V C G +C + +
Sbjct: 1883 DGNEKRPGDVWTLPDQCHT-VTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCG 1941
Query: 4848 CHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAA--- 4904
C T C + H +T DG+ + L GSCSYVL Q ++D ++L A
Sbjct: 1942 CRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-----NKEQDLEVILHNGACSPG 1996
Query: 4905 ---GDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLR 4961
G ++ + V + V L +VTV+G V++P G + V G M L
Sbjct: 1997 ARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
Query: 4962 LLF----DGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRA 5017
+F + L P F + GLCG + N ++DF+L +G+ + +T W
Sbjct: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEW-- 2114
Query: 5018 PGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCV 5077
+ + G+ C P + EE + C L P FA C VL+P+ ++ C
Sbjct: 2115 --TVQRPGQTCQP------ILEEQCLVPDSSHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
Query: 5078 YDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGS 5137
D C Q+ +C +A+Y C+ GV V WRT FC + CP Y+ C C
Sbjct: 2165 QDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
Query: 5138 CAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDC-------GCTHNGRYLPVNSSLL 5190
C ++ C EGC C ++ +G C+P + C G H + + +
Sbjct: 2220 CD--GNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQF----LEAWVP 2273
Query: 5191 TSDCSERCSCSSSSGLTCQAAGCPPGR-----VCEVKAEARN 5227
+ C+C S + C CP + +CEV +N
Sbjct: 2274 DHQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQN 2315
Score = 129 bits (324), Expect = 8e-29
Identities = 117/440 (26%), Positives = 176/440 (40%), Gaps = 42/440 (9%)
Query: 805 GLQLAPGQEVWA--DELCQRRCTCNGAT----HQVTCRD--KQSCPAGERCSVQNGLLGC 856
G + PG +VW D+ C +G T H+V C + SCP + GC
Sbjct: 1884 GNEKRPG-DVWTLPDQCHTVTCQPDGQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGC 1942
Query: 857 YPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQT 916
C GS H V+FDG+ F G+C+Y+L + Q+ + +L
Sbjct: 1943 RWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEV----ILHNGACSPGAR 1998
Query: 917 VSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFG 976
+++ V+ + V + + +V V+ L +P+ + +V V+ V G
Sbjct: 1999 QGCMKSIEVKHSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLG 2056
Query: 977 --LTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQE 1034
T T N P ++A GLCG + + A+D LR G + W
Sbjct: 2057 HIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTV 2116
Query: 1035 ETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCV 1092
+ RPG C C DS + C +L P F ECH L P C
Sbjct: 2117 Q-RPGQTCQPILEEQCLVPDS---------SHCQVLLLPL--FAECHKVLAPATFYAICQ 2164
Query: 1093 YDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLS 1152
D C +C+ +A+YA C+ G V WR+ + C +SCPP Y C +GCP
Sbjct: 2165 QDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPPSLVYNHCEHGCPRH 2219
Query: 1153 C-GDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASC-GCV-HQGTYHPPGQTFYPGPG 1209
C G++ CG EGC C + SC+P +C C+ G H + + P
Sbjct: 2220 CDGNV---SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQ 2276
Query: 1210 CDSLCHCQEGGLVSCESSSC 1229
+C C G V+C + C
Sbjct: 2277 PCQICTCLSGRKVNCTTQPC 2296
Score = 120 bits (302), Expect = 3e-26
Identities = 115/425 (27%), Positives = 170/425 (40%), Gaps = 44/425 (10%)
Query: 433 GRTVLSPVEPSCE-GMQ--CAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYD 489
G+T+L +C+ G++ C Q V GC VC H TFDG+ +
Sbjct: 1908 GQTLLKSHRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCPCVCTGSSTRHIVTFDGQNFK 1967
Query: 490 MMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS----RRVSYVGLVTVRAYSHSVSLTRG 545
+ G+CSY + + +D + H G+ R + + V+ + SV L
Sbjct: 1968 LTGSCSYVLFQNKEQDLEVIL--------HNGACSPGARQGCMKSIEVKHSALSVELHSD 2019
Query: 546 EVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY---DWDCQLALSLPAR 602
V V+ + +P + VY + V G + T+ + + QL LS P
Sbjct: 2020 ME--VTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKT 2076
Query: 603 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 662
F + GLCG + + A+DF+ DG + D W + C+ + C
Sbjct: 2077 FASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPDS 2136
Query: 663 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYA 722
Q +L L FA CH L P F C D C + +C +++YA
Sbjct: 2137 SHCQV--------LLLPL---FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYA 2181
Query: 723 QACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVC 782
C G+ V DWR+P C +SCP + Y C CP C+G S+C P EGC C
Sbjct: 2182 HLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDGNV--SSCGDHPS-EGCFC 2237
Query: 783 LPGFVASGGACVPASSC-GCTFQGLQLAPGQEVWA-DELCQRRCTCNGATHQVTCRDKQS 840
P V G+CVP +C C + E W D + CTC +V C Q
Sbjct: 2238 PPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSG-RKVNC-TTQP 2295
Query: 841 CPAGE 845
CP +
Sbjct: 2296 CPTAK 2300
Score = 115 bits (288), Expect = 1e-24
Identities = 124/500 (24%), Positives = 180/500 (36%), Gaps = 85/500 (17%)
Query: 4361 CGPP-----CPASCPSPAPLTTPAVCEG--------PCVEGCQCDAGFVLSADRCVPLNN 4407
C PP CPA L C+ CV GC C G V +RCV L
Sbjct: 767 CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
Query: 4408 GCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 4467
C C +H+ G E+ T C + VC + H C
Sbjct: 827 -CPC-----FHQ-GKEYAPGETVKIGCN------TCVCRDRKWNCTD---------HVCD 864
Query: 4468 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 4527
A C G HY+T DG ++ F G C+Y+L G G F + V N+ +
Sbjct: 865 ----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPS 918
Query: 4528 VSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVALPFQLDSLLHAHLSGADVVVTTTSG 4586
V + VT+ + + L DG V V P + ++ SG +++
Sbjct: 919 VKCKKRVTILVEGGEIEL---------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKA 969
Query: 4587 LSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKA----VGGKPA----GWQVGG 4638
LS+ +D + + + Y +CGLCGN++ +DL + V P W+V
Sbjct: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
Query: 4639 AQGCGECVSKP---CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 4695
+ C + P P+ C + +C ++ T C+ LV P Y C+
Sbjct: 1028 SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCI 1085
Query: 4696 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHS---------- 4743
D C + G C +A Y C G ++ WR CP C +
Sbjct: 1086 YDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEW 1144
Query: 4744 HYELCGDSCPVSCPSLSAPEGCESACREGC--VCDAGFVLSG--DTCVPVGQCG-CLHDG 4798
Y C +C V+C P C C EGC C G +L TCV C C G
Sbjct: 1145 RYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Query: 4799 RYYPLGEVFYPGPECERRCE 4818
R + G+ P C+
Sbjct: 1204 RRFASGKKVTLNPSDPEHCQ 1223
Score = 108 bits (271), Expect = 1e-22
Identities = 130/528 (24%), Positives = 190/528 (35%), Gaps = 97/528 (18%)
Query: 3160 CGPP-----CPASCPSPAPLTTPAVCEG--------PCVEGCQCDAGFVLSADRCVPLNN 3206
C PP CPA L C+ CV GC C G V +RCV L
Sbjct: 767 CRPPMVKLVCPADNLRAEGLECTKTCQNYDLECMSMGCVSGCLCPPGMVRHENRCVALER 826
Query: 3207 GCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 3266
C C +H+ G E+ T C + VC + H C
Sbjct: 827 -CPC-----FHQ-GKEYAPGETVKIGCN------TCVCRDRKWNCTD---------HVCD 864
Query: 3267 PVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQA 3326
A C G HY+T DG ++ F G C+Y+L G G F + V N+ +
Sbjct: 865 ----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSNPG--TFRILVGNKGCSHPS 918
Query: 3327 VSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVTLPFQLDSLLHAHLSGADVVVTTTSG 3385
V + VT+ + + L DG V V P + ++ SG +++
Sbjct: 919 VKCKKRVTILVEGGEIEL---------FDGEVNVKRPMKDETHFEVVESGRYIILLLGKA 969
Query: 3386 LSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKA----VGGKPA----GWQVGG 3437
LS+ +D + + + Y +CGLCGN++ +DL + V P W+V
Sbjct: 970 LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQVEEDPVDFGNSWKV-- 1027
Query: 3438 AQGCGECVSKP---CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCL 3494
+ C + P P+ C + +C ++ T C+ LV P Y C+
Sbjct: 1028 SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL--TSDVFQDCNKLVDPEPYLDVCI 1085
Query: 3495 LDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHS---------- 3542
D C + G C +A Y C G ++ WR CP C +
Sbjct: 1086 YDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWRTATLCPQSCEERNLRENGYECEW 1144
Query: 3543 HYELCGDSCPGSCPSLSAPEGCESACREGC--VCDAGFVLSG--DTCVPVGQCG-CLHDD 3597
Y C +C +C P C C EGC C G +L TCV C C
Sbjct: 1145 RYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPGKILDELLQTCVDPEDCPVCEVAG 1203
Query: 3598 RYYPLGQ--TFYPG-PGCDSLCRCREGGEVSCEPSSCGPHETCRPSGG 3642
R + G+ T P P +C C + ++C E C+ GG
Sbjct: 1204 RRFASGKKVTLNPSDPEHCQICHC-DVVNLTC--------EACQEPGG 1242
Score = 108 bits (271), Expect = 1e-22
Identities = 101/405 (24%), Positives = 162/405 (40%), Gaps = 47/405 (11%)
Query: 4465 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 4524
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
Query: 4525 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTT 4584
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
Query: 4585 SGLSLAF----DGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 4639
+ L F + F P +A+ GLCG +++ A+D G W+
Sbjct: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
Query: 4640 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 4696
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
Query: 4697 DACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSC 4756
D+C H +C +A+Y C+ G + +WR PDFC + CP Y C CP C
Sbjct: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
Query: 4757 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCL-HDGRYYPLGEVFYPG 4810
+G S+C EGC C V+ +CVP C C+ DG + E + P
Sbjct: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
Query: 4811 PECERRCECGPGGHVTC-------QEGAACGPHEECRLEDGVQAC 4848
+ + C C G V C + CG E RL C
Sbjct: 2275 HQPCQICTCLSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQC 2319
Score = 107 bits (268), Expect = 2e-22
Identities = 122/491 (24%), Positives = 181/491 (36%), Gaps = 84/491 (17%)
Query: 1983 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 2042
CV GC C G V +RCV L C C +H+ G E+ T C + V
Sbjct: 804 CVSGCLCPPGMVRHENRCVALER-CPC-----FHQ-GKEYAPGETVKIGCN------TCV 850
Query: 2043 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPC 2102
C + H C A C G HY+T DG ++ F G C+Y+L
Sbjct: 851 CRDRKWNCTD---------HVCD----ATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDY 897
Query: 2103 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDG-VFVTLP 2161
G G F + V N+ +V + VT+ + + L DG V V P
Sbjct: 898 CGSNPG--TFRILVGNKGCSHPSVKCKKRVTILVEGGEIEL---------FDGEVNVKRP 946
Query: 2162 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADD 2221
+ ++ SG +++ LS+ +D + + + Y +CGLCGN++ +D
Sbjct: 947 MKDETHFEVVESGRYIILLLGKALSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNND 1006
Query: 2222 LKA----VGGKPA----GWQVGGAQGCGECVSKP---CPSPCTPEQQESFGGPDACGVIS 2270
L + V P W+V + C + P P+ C + +C ++
Sbjct: 1007 LTSSNLQVEEDPVDFGNSWKV--SSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRIL- 1063
Query: 2271 ATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWR 2328
T C+ LV P Y C+ D C + G C +A Y C G ++ WR
Sbjct: 1064 -TSDVFQDCNKLVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHG-KVVTWR 1121
Query: 2329 RPDFCPFQCPAHS----------HYELCGDSCPGSCPSLSAPEGCESACREGC--VCDAG 2376
CP C + Y C +C +C P C C EGC C G
Sbjct: 1122 TATLCPQSCEERNLRENGYECEWRYNSCAPACQVTCQH-PEPLACPVQCVEGCHAHCPPG 1180
Query: 2377 FVLSG--DTCVPVGQCG-CLHDDRYYPLGQ--TFYPG-PGCDSLCRCREGGEVSCEPSSC 2430
+L TCV C C R + G+ T P P +C C + ++C
Sbjct: 1181 KILDELLQTCVDPEDCPVCEVAGRRFASGKKVTLNPSDPEHCQICHC-DVVNLTC----- 1234
Query: 2431 GPHETCRPSGG 2441
E C+ GG
Sbjct: 1235 ---EACQEPGG 1242
Score = 106 bits (265), Expect = 5e-22
Identities = 94/382 (24%), Positives = 155/382 (40%), Gaps = 40/382 (10%)
Query: 2063 GCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 2122
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
Query: 2123 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTT 2182
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
Query: 2183 SGLSLAF----DGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 2237
+ L F + F P +A GLCG +++ A+D G W+
Sbjct: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
Query: 2238 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 2294
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
Query: 2295 DACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSC 2354
D+C H +C +A+Y C+ G + +WR PDFC CP Y C CP C
Sbjct: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
Query: 2355 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCLHDDR-YYPLGQTFYPG 2408
+G S+C EGC C V+ +CVP C C+ +D + + + P
Sbjct: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
Query: 2409 PGCDSLCRCREGGEVSCEPSSC 2430
+C C G +V+C C
Sbjct: 2275 HQPCQICTCLSGRKVNCTTQPC 2296
Score = 106 bits (264), Expect = 7e-22
Identities = 94/382 (24%), Positives = 155/382 (40%), Gaps = 40/382 (10%)
Query: 3264 GCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG 3323
GC+ C H VT DG F G+C Y+L E + +
Sbjct: 1941 GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ-------NKEQDLEVILHNGAC 1993
Query: 3324 SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTT 3383
S ++++ + +L++ ++ V+G V++P+ + + ++ GA +
Sbjct: 1994 SPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPY-VGGNMEVNVYGAIMHEVRF 2052
Query: 3384 SGLSLAF----DGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK-PAGWQVGGA 3438
+ L F + F P +A GLCG +++ A+D G W+
Sbjct: 2053 NHLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQ 2112
Query: 3439 QGCGECVSKPCPSPCTPEQQESFGGPDA--CGVISATDGPL-APCHGLVPPAQYFQGCLL 3495
+ V +P + C P +E PD+ C V+ PL A CH ++ PA ++ C
Sbjct: 2113 EWT---VQRPGQT-CQPILEEQCLVPDSSHCQVLLL---PLFAECHKVLAPATFYAICQQ 2165
Query: 3496 DACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSC 3555
D+C H +C +A+Y C+ G + +WR PDFC CP Y C CP C
Sbjct: 2166 DSC----HQEQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHC 2220
Query: 3556 PSLSAPEGCESAC----REGCVCDAGFVLSGDTCVPVGQC-GCLHDDR-YYPLGQTFYPG 3609
+G S+C EGC C V+ +CVP C C+ +D + + + P
Sbjct: 2221 ------DGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPD 2274
Query: 3610 PGCDSLCRCREGGEVSCEPSSC 3631
+C C G +V+C C
Sbjct: 2275 HQPCQICTCLSGRKVNCTTQPC 2296
Score = 105 bits (262), Expect = 1e-21
Identities = 127/503 (25%), Positives = 183/503 (36%), Gaps = 97/503 (19%)
Query: 1193 HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS--------SCGPHEACQPSGGSLGC 1244
H T P GQT +C G SC +S +CG C C
Sbjct: 1900 HTVTCQPDGQTLLKS----HRVNCDRGLRPSCPNSQSPVKVEETCGCRWTCP-------C 1948
Query: 1245 VAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 1304
V GSST H TFDG+ F G+C YVL Q L +L R
Sbjct: 1949 VCTGSST------RHIVTFDGQNFKLTGSCSYVLFQ--NKEQDLE--VILHNGACSPGAR 1998
Query: 1305 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
+ I V+ + ++ L +VTVNG + +P V G + + +G+ ++ E F
Sbjct: 1999 QGCMKSIEVKHSALSVELHS-DMEVTVNGRLVSVPYV--GGNMEVNVYGA-IMHEVRFN- 2053
Query: 1365 RVAYDLVYYVRVTVPGNYYQ----------QMCGLCGNYNGDPKDDFQKPNGSQAGNANE 1414
L + T N +Q + GLCG + + +DF +G+ +
Sbjct: 2054 ----HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKT 2109
Query: 1415 FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSC 1474
W P C P E C+ C +L P + C
Sbjct: 2110 LVQEWTVQRPGQTCQPIL-----EEQCL------------VPDSSHCQVLLLPL--FAEC 2150
Query: 1475 HKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPP 1534
HK++ P C D C + +C I +Y C+ G V+ WRT FC M CPP
Sbjct: 2151 HKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPDFCAMSCPP 2205
Query: 1535 NSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQC-GCY-HNGV 1592
+ Y C C C + C D +EGC C + +CVP + C C +GV
Sbjct: 2206 SLVYNHCEHGCPRHCDGNVS--SCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGV 2263
Query: 1593 YYEPEQTVLIDN--CRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTC 1650
++ + + D+ C Q CTC +G+ + C C K P TC
Sbjct: 2264 QHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP--------------TAKAP----TC 2304
Query: 1651 RPQETCKEQGGQGVCLPNYEATC 1673
E + + C P YE C
Sbjct: 2305 GLCEVARLRQNADQCCPEYECVC 2327
Score = 101 bits (251), Expect = 2e-20
Identities = 128/511 (25%), Positives = 181/511 (35%), Gaps = 90/511 (17%)
Query: 2381 GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGP---HETCR 2437
GD QC H P GQT + C G SC P+S P ETC
Sbjct: 1890 GDVWTLPDQC---HTVTCQPDGQTLLKSHRVN----CDRGLRPSC-PNSQSPVKVEETC- 1940
Query: 2438 PSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQE 2497
GC C S H TFDG+ F G+C YVL Q L +L
Sbjct: 1941 ------GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ--NKEQDLE--VILHN 1990
Query: 2498 NVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDV 2557
R + I V+ + ++ L +VTVNG + +P V G + + +G+ +
Sbjct: 1991 GACSPGARQGCMKSIEVKHSALSVELHS-DMEVTVNGRLVSVPYV--GGNMEVNVYGA-I 2046
Query: 2558 VIETDFGLRVAYDLVYYVRVTVPGNYYQLMC----------GLCGNYNGDPKDDFQKPNG 2607
+ E F L + T N +QL GLCG + + +DF +G
Sbjct: 2047 MHEVRFN-----HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDG 2101
Query: 2608 SQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSS 2667
+ + W P C P I E+C C +L
Sbjct: 2102 TVTTDWKTLVQEWTVQRPGQTCQP-----------ILEEQC------LVPDSSHCQVLLL 2144
Query: 2668 PTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNET 2727
P + CHK++ P C D C + +C I +Y C+ G V+ WR
Sbjct: 2145 PL--FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPD 2197
Query: 2728 FCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQC- 2786
FC M CP + Y C C C + C D +EGC C + +CVP + C
Sbjct: 2198 FCAMSCPPSLVYNHCEHGCPRHCDGNVS--SCGDHPSEGCFCPPDKVMLEGSCVPEEACT 2255
Query: 2787 GCY-HNGAYYEPEQTVLIDN--CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNK 2843
C +G ++ + + D+ C Q CTC G+ V C C +
Sbjct: 2256 QCIGEDGVQHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCPTAK-------------- 2300
Query: 2844 DPCHGVTCRPQETCKEQGGQGVCLPNYEATC 2874
TC E + + C P YE C
Sbjct: 2301 ----APTCGLCEVARLRQNADQCCPEYECVC 2327
Score = 101 bits (251), Expect = 2e-20
Identities = 130/511 (25%), Positives = 182/511 (35%), Gaps = 90/511 (17%)
Query: 3582 GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGP---HETCR 3638
GD QC H P GQT + C G SC P+S P ETC
Sbjct: 1890 GDVWTLPDQC---HTVTCQPDGQTLLKSHRVN----CDRGLRPSC-PNSQSPVKVEETC- 1940
Query: 3639 PSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQE 3698
GC C S H TFDG F G+C YVL Q L +L
Sbjct: 1941 ------GCRWTCPCVCTGSSTRHIVTFDGQNFKLTGSCSYVLFQ--NKEQDLE--VILHN 1990
Query: 3699 NVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDV 3758
R + I V+ + ++ L +VTVNG + +P V G + + +G+ +
Sbjct: 1991 GACSPGARQGCMKSIEVKHSALSVELHS-DMEVTVNGRLVSVPYV--GGNMEVNVYGA-I 2046
Query: 3759 VIETDFGLRVAYDLVYYVRVTVPGNYYQLMC----------GLCGNYNGDPKDDFQKPNG 3808
+ E F L + T N +QL GLCG + + +DF +G
Sbjct: 2047 MHEVRFN-----HLGHIFTFTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDG 2101
Query: 3809 SQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSS 3868
+ + W P C P I ++C C +L
Sbjct: 2102 TVTTDWKTLVQEWTVQRPGQTCQP-----------ILEEQC------LVPDSSHCQVLLL 2144
Query: 3869 PTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNET 3928
P + CHK++ P C D C + +C I +Y C+ G V+ WR
Sbjct: 2145 PL--FAECHKVLAPATFYAICQQDSC----HQEQVCEVIASYAHLCRTNGVCVD-WRTPD 2197
Query: 3929 FCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQC- 3987
FC M CP + Y C C C + C D +EGC C + +CVP + C
Sbjct: 2198 FCAMSCPPSLVYNHCEHGCPRHCDGNVS--SCGDHPSEGCFCPPDKVMLEGSCVPEEACT 2255
Query: 3988 GCY-HNGVYYEPEQTVLIDN--CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTK 4044
C +GV ++ + + D+ C Q CTC G+ V C C K
Sbjct: 2256 QCIGEDGVQHQFLEAWVPDHQPC-QICTCLSGRKVNCTTQPCP--------------TAK 2300
Query: 4045 DPCHGVTCRPQETCKEQGGQGVCLPNYEATC 4075
P TC E + + C P YE C
Sbjct: 2301 AP----TCGLCEVARLRQNADQCCPEYECVC 2327
Score = 91.7 bits (226), Expect = 2e-17
Identities = 114/468 (24%), Positives = 166/468 (35%), Gaps = 75/468 (16%)
Query: 1643 DPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP-------- 1679
D CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 1897 DQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSST 1955
Query: 1680 -HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 1738
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 1956 RHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEVK 2008
Query: 1739 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSY-DWNW 1797
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 2009 HSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNN 2066
Query: 1798 RVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 1856
+ L P ++ GLCG D N ND + +GT+ W C
Sbjct: 2067 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 2126
Query: 1857 CRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 1916
C + P F CH + P +F+ C D C +
Sbjct: 2127 LEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC----HQ 2170
Query: 1917 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTP 1976
+ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 2171 EQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-----NV 2224
Query: 1977 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCG 2035
+ C EGC C V+ CVP C +G H+ + D Q C C
Sbjct: 2225 SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC- 2283
Query: 2036 PGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 2068
G + CT +CGL EV L P + C PVS
Sbjct: 2284 LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
Score = 91.3 bits (225), Expect = 2e-17
Identities = 114/468 (24%), Positives = 166/468 (35%), Gaps = 75/468 (16%)
Query: 2844 DPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP-------- 2880
D CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 1897 DQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSST 1955
Query: 2881 -HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 2939
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 1956 RHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEVK 2008
Query: 2940 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSY-DWNW 2998
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 2009 HSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNN 2066
Query: 2999 RVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 3057
+ L P ++ GLCG D N ND + +GT+ W C
Sbjct: 2067 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 2126
Query: 3058 CRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 3117
C + P F CH + P +F+ C D C +
Sbjct: 2127 LEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC----HQ 2170
Query: 3118 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 3177
+ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 2171 EQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-----NV 2224
Query: 3178 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCG 3236
+ C EGC C V+ CVP C +G H+ + D Q C C
Sbjct: 2225 SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC- 2283
Query: 3237 PGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 3269
G + CT +CGL EV L P + C PVS
Sbjct: 2284 LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
Score = 91.3 bits (225), Expect = 2e-17
Identities = 114/468 (24%), Positives = 166/468 (35%), Gaps = 75/468 (16%)
Query: 4045 DPCHGVTCRP--QETCK------EQGGQGVCLPN------YEATCWL-WGDP-------- 4081
D CH VTC+P Q K ++G + C PN E TC W P
Sbjct: 1897 DQCHTVTCQPDGQTLLKSHRVNCDRGLRPSC-PNSQSPVKVEETCGCRWTCPCVCTGSST 1955
Query: 4082 -HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 4140
H +FDG+ F G+C+YVL Q L + ++ + V
Sbjct: 1956 RHIVTFDGQNFKLTGSCSYVLFQN-----KEQDLE--VILHNGACSPGARQGCMKSIEVK 2008
Query: 4141 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSY-DWNW 4199
++ +H D +V VNG L ++P + ++V + G ++ N
Sbjct: 2009 HSALSVELHSDM--EVTVNGRLVSVPYVGGNMEVNVYGAIMHEVRFNHLGHIFTFTPQNN 2066
Query: 4200 RVDVTL-PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDE 4258
+ L P ++ GLCG D N ND + +GT+ W C
Sbjct: 2067 EFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPGQTCQPI 2126
Query: 4259 CRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDR 4318
C + P F CH + P +F+ C D C +
Sbjct: 2127 LEEQCLVPDSSHCQVLLLP------------LFAECHKVLAPATFYAICQQDSC----HQ 2170
Query: 4319 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 4378
+ +C+ +ASY C+ GV + DWR C ++CP + Y C CP C
Sbjct: 2171 EQVCEVIASYAHLCRTNGVCV-DWRTPDFCAMSCPPSLVYNHCEHGCPRHCDG-----NV 2224
Query: 4379 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCG 4437
+ C EGC C V+ CVP C +G H+ + D Q C C
Sbjct: 2225 SSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTC- 2283
Query: 4438 PGGGSLVCT--------PASCGLGEVCGL-------LPSGQHGCQPVS 4470
G + CT +CGL EV L P + C PVS
Sbjct: 2284 LSGRKVNCTTQPCPTAKAPTCGLCEVARLRQNADQCCPEYECVCDPVS 2331
Score = 39.3 bits (90), Expect = 0.11
Identities = 45/169 (26%), Positives = 66/169 (39%), Gaps = 29/169 (17%)
Query: 2747 SLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQC----GCYHNGAYYEPEQTVL 2802
++ C L P+ CP G C+ AC P +C C NG P +TV+
Sbjct: 2546 NVSCPQLEVPV-CPSGFQLSCKTS--------ACCPSCRCERMEACMLNGTVIGPGKTVM 2596
Query: 2803 IDNCRQ-QCTCHVGKV----VVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETC 2857
ID C +C VG + + C++ +C P + G N C G T
Sbjct: 2597 IDVCTTCRCMVQVGVISGFKLECRKTTCNPCPL-----GYKEENNTGECCGRCLPTACTI 2651
Query: 2858 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCP 2906
+ +GGQ + L E T D H+ K + +G + TGCP
Sbjct: 2652 QLRGGQIMTLKRDE-TLQDGCDTHF-----CKVNERGEYFWEKRVTGCP 2694
Score = 37.4 bits (85), Expect = 0.41
Identities = 26/90 (28%), Positives = 39/90 (43%), Gaps = 18/90 (20%)
Query: 3948 SLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQC----GCYHNGVYYEPEQTVL 4003
++ C L P+ CP G C+ AC P +C C NG P +TV+
Sbjct: 2546 NVSCPQLEVPV-CPSGFQLSCKTS--------ACCPSCRCERMEACMLNGTVIGPGKTVM 2596
Query: 4004 IDNCRQ-QCTCHVGKV----VVCQEHSCKP 4028
ID C +C VG + + C++ +C P
Sbjct: 2597 IDVCTTCRCMVQVGVISGFKLECRKTTCNP 2626
Score = 35.4 bits (80), Expect = 1.5
Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 23/121 (19%)
Query: 1129 EELCPLSCPPHS-----HYEACS-YGCPLSCGDLPVP---GGCGSECHEGCVCDEGFALS 1179
+ + P SCPPH + C Y C +C + V G S C C +
Sbjct: 2368 KRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGC------T 2421
Query: 1180 GESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHC--QEGGLVSCESSSCGPHEACQP 1237
+CLP CVH+ T +P GQ + GCD +C C E ++ + C + C+
Sbjct: 2422 TTTCLP--DKVCVHRSTIYPVGQ--FWEEGCD-VCTCTDMEDAVMGLRVAQCS-QKPCED 2475
Query: 1238 S 1238
S
Sbjct: 2476 S 2476
Score = 34.7 bits (78), Expect = 2.6
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 13/71 (18%)
Query: 1568 CDSGFLYNGQ--ACVPIQQC----GCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMV--- 1618
C SGF + + AC P +C C NG P +TV+ID C C C G++
Sbjct: 2557 CPSGFQLSCKTSACCPSCRCERMEACMLNGTVIGPGKTVMIDVC-TTCRCMVQVGVISGF 2615
Query: 1619 ---CQEHSCKP 1626
C++ +C P
Sbjct: 2616 KLECRKTTCNP 2626
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 366 bits (940), Expect = e-100
Identities = 351/1274 (27%), Positives = 505/1274 (39%), Gaps = 186/1274 (14%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 3332
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 3333 VTLQIYNHSLTLSARWPRKLQV-DGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 3391
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 3392 GDSFVRLRVPAAYAGSLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 3443
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 3444 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 3503
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 3504 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563
+C VA + C AG + WR CP CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSL 320
Query: 3564 CESACREGCVCDAGFVLS--GDT-CVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLCRCR 3619
CE +GC C G V GD+ CVPV QC C LH Y P GQ C+ C C
Sbjct: 321 CEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTP-GQEI--TNDCEQ-CVCN 376
Query: 3620 EGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYV 3679
G V C+ C TC G H TTFDG + F G C YV
Sbjct: 377 AGRWV-CKDLPC-------------------PGTCALEGGSHITTFDGKTYTFHGDCYYV 416
Query: 3680 LAQTCGTRPGLHR--FAVLQENVAWG--NGRVSVTRVITVQVANFTLRLEQRQWKVTVNG 3735
LA+ G H +A+L E G + + + V+ + + + + V +N
Sbjct: 417 LAK------GDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGSVLLNE 470
Query: 3736 VDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 3794
+ + LP V A+ + R S + V + L+V V + VT+ + GLCGN
Sbjct: 471 LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 530
Query: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELE 3854
+NG DDF+ +G F N+W+ S C D C +E
Sbjct: 531 FNGLEGDDFKTASGLVEATGAGFANTWK---AQSSCHDKLDW--------LDDPCSLNIE 579
Query: 3855 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 3914
E +C LL P CH VDP K C +D C N LC+ + +Y AC
Sbjct: 580 SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 639
Query: 3915 QAAGGHVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALS-APLQCPDGCA--EGC 3968
A G + WR E C + CP + + TC C +LS A C +G A +GC
Sbjct: 640 TAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGC 698
Query: 3969 QC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKV--------- 4018
C D FL CVP+ +C CYH G+Y E V+ ++C C G++
Sbjct: 699 GCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQIRLIG 756
Query: 4019 -------------------------VVCQ-------EHSCKPGQVCQPSG----GILSCV 4042
+ CQ C G VC P G G CV
Sbjct: 757 QSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDGRGGCV 815
Query: 4043 TKDPC---HG-----------VTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYHSFD 4087
+ C H V C TC + G+ VC TC ++G HY +FD
Sbjct: 816 VEKECPCVHNNDLYSSGAKIKVDC---NTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFD 872
Query: 4088 GRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 4147
G+ +DF G C+YV C S+ G F++ T+N G V+ + + + T +
Sbjct: 873 GKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTELK 930
Query: 4148 IH-KDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLP 4206
+ K + R G A G+ V + ++ G+ V +D V + L
Sbjct: 931 LEDKHRVVIQRDEGHHVAYTTREV-GQYLVVESST--------GIIVIWDKRTTVFIKLA 981
Query: 4207 SSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTC 4266
SY G VCGLCGN D NND + + S +G SW+ P C D P C
Sbjct: 982 PSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNPEP-C 1037
Query: 4267 PEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCKA 4324
+ + C L S F+ CH+ V P+ F++ CV D C GGD + C A
Sbjct: 1038 SLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSA 1094
Query: 4325 LASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSPAPL-- 4375
+ASY C G + WR C I C + HYE CG +C + +
Sbjct: 1095 VASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHS 1153
Query: 4376 -TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQW 4433
+ + EG C C D + +CV + CGC+ T++ G+ + TC
Sbjct: 1154 NISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEETCKS- 1210
Query: 4434 CRCGPGGGSLVCTP 4447
C C +VC P
Sbjct: 1211 CVC-TNSSQVVCRP 1223
Score = 364 bits (935), Expect = 1e-99
Identities = 349/1275 (27%), Positives = 506/1275 (39%), Gaps = 188/1275 (14%)
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 2132 VTLQIYNHSLTLSARWPRKLQV-DGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2190
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 2191 GDSFVRLRVPAAYAGSLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 2242
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
+C VA + C AG + WR CP CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSL 320
Query: 2363 CESACREGCVCDAGFVLS--GDT-CVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLCRCR 2418
CE +GC C G V GD+ CVPV QC C LH Y P GQ C+ C C
Sbjct: 321 CEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTP-GQEI--TNDCEQ-CVCN 376
Query: 2419 EGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYV 2478
G V C+ C TC G H TTFDG+ + F G C YV
Sbjct: 377 AGRWV-CKDLPC-------------------PGTCALEGGSHITTFDGKTYTFHGDCYYV 416
Query: 2479 LAQTCGTRPGLHR--FAVLQENVAWG--NGRVSVTRVITVQVANFTLRLEQRQWKVTVNG 2534
LA+ G H +A+L E G + + + V+ + + + + V +N
Sbjct: 417 LAK------GDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGSVLLNE 470
Query: 2535 VDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGN 2593
+ + LP V A+ + R S + V + L+V V + VT+ + GLCGN
Sbjct: 471 LQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGN 530
Query: 2594 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELE 2653
+NG DDF+ +G F N+W+ +C + + C +E
Sbjct: 531 FNGLEGDDFKTASGLVEATGAGFANTWK---------AQSSCHDKLDWL--DDPCSLNIE 579
Query: 2654 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713
E +C LL P CH VDP K C +D C N LC+ + +Y AC
Sbjct: 580 SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 639
Query: 2714 QAAGGQVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALS-APLQCPDGCA--EGC 2767
A G + WR E C + CP + + TC C +LS A C +G A +GC
Sbjct: 640 TAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGC 698
Query: 2768 QC-DSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKV--------- 2817
C D FL CVP+ +C CYH G Y E V+ ++C C G++
Sbjct: 699 GCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQIRLIG 756
Query: 2818 -------------------------VVCQ-------EHSCKPGQVCQPSG----GILSCV 2841
+ CQ C G VC P G G CV
Sbjct: 757 QSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDGRGGCV 815
Query: 2842 NKDPC---HG-----------VTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYHSFD 2886
+ C H V C TC + G+ VC TC ++G HY +FD
Sbjct: 816 VEKECPCVHNNDLYSSGAKIKVDC---NTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFD 872
Query: 2887 GRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 2946
G+ +DF G C+YV C S+ G F++ T+N G V+ + + + T +
Sbjct: 873 GKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTELK 930
Query: 2947 IH-KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV-ADFGLQVSYDWNWRVDVTL 3004
+ K + R G A T+ + L+V + G+ V +D V + L
Sbjct: 931 LEDKHRVVIQRDEGHHVAY----------TTREVGQYLVVESSTGIIVIWDKRTTVFIKL 980
Query: 3005 PSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT 3064
SY G VCGLCGN D NND + + S +G SW+ P C D P
Sbjct: 981 APSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNPEP- 1036
Query: 3065 CPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILCK 3122
C + + C L F+ CH+ V P+ F++ CV D C GGD + C
Sbjct: 1037 CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCS 1093
Query: 3123 ALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSPAPL- 3174
A+ASY C G + WR C I C + HYE CG +C + +
Sbjct: 1094 AVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIH 1152
Query: 3175 --TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231
+ + EG C C D + +CV + CGC+ T++ G+ + TC
Sbjct: 1153 SNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEETCKS 1210
Query: 3232 WCRCGPGGGSLVCTP 3246
C C +VC P
Sbjct: 1211 -CVC-TNSSQVVCRP 1223
Score = 346 bits (888), Expect = 3e-94
Identities = 337/1278 (26%), Positives = 505/1278 (39%), Gaps = 187/1278 (14%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C G+ HY +FDG F F G C Y C + F V ++ ++ + ++
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQ---YLP---FQAADGQVQVFRQGRDAVVRTDFGL 977
+ + + + R VL V+ Y P + +D +V+ + GL
Sbjct: 95 LLTIKDDTIYLTRHLA--VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA---------GL 143
Query: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1037
T+ ++ + ++ + + CGLCG++NG + L G + L FGN Q+ +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNM-QKINQ 201
Query: 1038 PGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097
P +P + + A + + EC L + F +C + + +R C DRC
Sbjct: 202 PDVVCEDPEE----EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCR 256
Query: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLP 1157
PG +C +A ++ C AG WR+ LCP +CP + Y C +C L
Sbjct: 257 CPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLE 316
Query: 1158 VPGGCGSECHEGCVCDEGFA---LSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLC 1214
V C +GC C EG + C+P++ C C G + PGQ C+ C
Sbjct: 317 VSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEI--TNDCEQ-C 373
Query: 1215 HCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTC 1274
C G V C+ C TC G H TTFDG+ + F G C
Sbjct: 374 VCNAGRWV-CKDLPC-------------------PGTCALEGGSHITTFDGKTYTFHGDC 413
Query: 1275 VYVLAQTCGTRPGLHR--FAVLQENVAWG--NGRVSVTRVITVQVANFTLRLEQRQWKVT 1330
YVLA+ G H +A+L E G + + + V+ + + + + V
Sbjct: 414 YYVLAK------GDHNDSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVFKSDGSVL 467
Query: 1331 VNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGL 1389
+N + + LP V A+ + R S + V + L+V V + VT+ Q+ GL
Sbjct: 468 LNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGL 527
Query: 1390 CGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPP 1449
CGN+NG DDF+ +G F N+W+ S C D + C
Sbjct: 528 CGNFNGLEGDDFKTASGLVEATGAGFANTWK---AQSSC-------HDKLDWL-DDPCSL 576
Query: 1450 ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYV 1509
+E E +C LL P CH VDP K C +D C N LC+ + +Y
Sbjct: 577 NIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYA 636
Query: 1510 SACQAAGGHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALS-APPQCQDGCA-- 1563
AC A G + WR E C + CP + + TC C +LS A C +G A
Sbjct: 637 RACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPV 695
Query: 1564 EGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG-------- 1614
+GC C D FL CVP+ +C CYH G+Y E V+ ++C C G
Sbjct: 696 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV--RQEERCVCRDGRLHCRQIR 753
Query: 1615 --------------------------KGMVCQ-------EHSCKPGQVCQPSG----GIL 1637
+ + CQ C G VC P G G
Sbjct: 754 LIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDGRG 812
Query: 1638 SCVTKDPC---HG-----------VTCRPQETCKEQGGQGVCLPNY-EATCWLWGDPHYH 1682
CV + C H V C TC + G+ VC TC ++G HY
Sbjct: 813 GCVVEKECPCVHNNDLYSSGAKIKVDC---NTCTCKRGRWVCTQAVCHGTCSIYGSGHYI 869
Query: 1683 SFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGT 1742
+FDG+ +DF G C+YV C S+ G F++ T+N G V+ + + + T
Sbjct: 870 TFDGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRT 927
Query: 1743 NISIH-KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV-ADFGLQVSYDWNWRVD 1800
+ + K + R G A T+ + L+V + G+ V +D V
Sbjct: 928 ELKLEDKHRVVIQRDEGHHVAY----------TTREVGQYLVVESSTGIIVIWDKRTTVF 977
Query: 1801 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGS 1860
+ L SY G VCGLCGN D NND + + S +G SW+ P C D
Sbjct: 978 IKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNP 1034
Query: 1861 CPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDI 1918
P C + + C L F+ CH+ V P+ F++ CV D C GGD +
Sbjct: 1035 EP-CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCEC 1090
Query: 1919 LCKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGSPCPASCPSPA 1971
C A+ASY C G + WR C I C + HYE CG+ +C +
Sbjct: 1091 FCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTIN 1149
Query: 1972 PL---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGT 2027
+ + + EG C C D + +CV + CGC+ T++ G+ + T
Sbjct: 1150 GIHSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEET 1207
Query: 2028 CSQWCRCGPGGGSLVCTP 2045
C C C +VC P
Sbjct: 1208 CKS-CVC-TNSSQVVCRP 1223
Score = 304 bits (778), Expect = 2e-81
Identities = 310/1265 (24%), Positives = 480/1265 (37%), Gaps = 209/1265 (16%)
Query: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134
C WG+ HY +FDG F F G C+Y A+ C G + F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASD-CRGSYKE----FAVHLKRGPGQAEAPAGV 91
Query: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVAQGASKALLVADFGLQ 4192
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 4252
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 4253 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311
+C D P +C E R E C L T F C VP E + + C D
Sbjct: 204 VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
Query: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 4371
C G +C +A + C AG +WR C TCP N Y G PC +C
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC-- 312
Query: 4372 PAPLTTPAVCEGPCVEGCQCDAGFV---LSADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
+ L ++CE ++GC C G V + CVP++ C C +G + G E D
Sbjct: 313 -SHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQ-CHCRLHGHLYTPGQEITND- 369
Query: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 4488
C Q C C G VC C C G H T DG
Sbjct: 370 -CEQ-CVC--NAGRWVCKDLPC--------------------PGTCALEGGSHITTFDGK 405
Query: 4489 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTLQIYNHSLTLSA 4547
+ F G C Y+L+ H +++ + GS + ++V L +
Sbjct: 406 TYTFHGDCYYVLAKGDHN-----DSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVF 460
Query: 4548 RWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAA 4607
+ + ++ + V LP S S ++V+ G+ L ++L V A+
Sbjct: 461 KSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQAS 520
Query: 4608 --SLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQE 4660
+ GLCGN+N DD K G G A + C K PC+ +
Sbjct: 521 QGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIES 580
Query: 4661 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 4720
+ C ++ T+ P CH V PA+Y++ C D C Q + LC A+++Y AC
Sbjct: 581 ANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACT 640
Query: 4721 AAGAQLGEWRRPDFCPL---QCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE------ 4771
A G L WR C CP + +C +C SLS +S C E
Sbjct: 641 AKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVD 696
Query: 4772 GCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG-------- 4822
GC C D F+ CVP+ +C C H G Y G+V E RC C G
Sbjct: 697 GCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV---RQEERCVCRDGRLHCRQIR 753
Query: 4823 --------------------------GHVTCQEGAACGPHEEC---------RLEDGVQA 4847
++CQ AA H EC ++DG
Sbjct: 754 LIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGG 813
Query: 4848 C--------------HATG------CGRCLANGGI------------------HYITLDG 4869
C +++G C C G HYIT DG
Sbjct: 814 CVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDG 873
Query: 4870 RVYDLHGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDL-----QRLLVTVAGQVVSLAQ 4923
+ YD G CSYV Q C FSI+ E G + + + + + L
Sbjct: 874 KYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLED 933
Query: 4924 GQQVTV---DGEAVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
+V + +G VA T E G+ +V++++ G+ +++D + + + ++
Sbjct: 934 KHRVVIQRDEGHHVAY--------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYK 985
Query: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
G +CGLCGNF+ ++DF + SS FG +W+ + P C
Sbjct: 986 GTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP-----CSLN 1040
Query: 5040 ETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAY 5097
+ + C L++ F+ C + + P ++ CV+D C+ GD C ++A+Y
Sbjct: 1041 PHRRSWAEKQCSILKS--SVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASY 1098
Query: 5098 TAACQAAGVAVKPWRTDSFCPLHC----PAHS---HYSICTRTCQGSCAALSGL-TGCTT 5149
C G V WRT CP+ C P H HY C +C ++G+ + +
Sbjct: 1099 AQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISV 1157
Query: 5150 RCFEGC--EC-DDRFLLSQGV--CIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 5204
EGC C DR + + + C+ CGC + P +S+ T + + C C++SS
Sbjct: 1158 SYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSS 1217
Query: 5205 GLTCQ 5209
+ C+
Sbjct: 1218 QVVCR 1222
Score = 287 bits (734), Expect = 2e-76
Identities = 269/1033 (26%), Positives = 403/1033 (39%), Gaps = 189/1033 (18%)
Query: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 4533
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 4534 VTLQIYNHSLTLSARWPRKLQV-DGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 4592
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 4593 GDSFVRLRVPAAYAASLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 4644
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 4645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 4704
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 4705 PGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEG 4764
+C VA + C AG + G WR CP CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTCSHLEVSSL 320
Query: 4765 CESACREGCVCDAGFVLS--GDT-CVPVGQCGC-LHDGRYYPLGEVFYPGPECERRCECG 4820
CE +GC C G V GD+ CVPV QC C LH G ++ PG E C
Sbjct: 321 CEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLH-------GHLYTPGQEITNDC--- 370
Query: 4821 PGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCS 4879
E+C G C C G C GG H T DG+ Y HG C
Sbjct: 371 ----------------EQCVCNAGRWVCKDLPCPGTCALEGGSHITTFDGKTYTFHGDCY 414
Query: 4880 YVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTV----DGEAVA 4935
YVLA+ H ++ ++++ E G + T VV LA ++ V DG +
Sbjct: 415 YVLAKGDH----NDSYALLGELAPCGSTDK--QTCLKTVVLLADKKKNVVVFKSDGSVLL 468
Query: 4936 LPVAVGRVRVTA-------EGRNMVLQTTKGLRLLFD--GDAHLLMSIPSPFRGRLCGLC 4986
+ V VTA ++++ G+RL L +++ +G++ GLC
Sbjct: 469 NELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLC 528
Query: 4987 GNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYES 5046
GNFNG DDF +G ++ F W+A S C + P L E+A Y +
Sbjct: 529 GNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CHDKLDWLDDPCSLNIESANY-A 584
Query: 5047 NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGV 5106
C L+ + PF C + + P+EY+++C YD C + ++ LC +L++Y AC A GV
Sbjct: 585 EHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGV 644
Query: 5107 AVKPWRTDSFCPL---HCPAHSHYSICTRTCQGSCAALSGLTGCTTRCF---EGCECDDR 5160
+ WR + C CP + TCQ +C +LS F +GC C D
Sbjct: 645 MLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDH 703
Query: 5161 -FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC------------------- 5200
FL +G C+P+ C C H G YL ++ + ERC C
Sbjct: 704 TFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRDGRLHCRQIRLIGQSCTA 761
Query: 5201 ---------------SSSSGLTCQ--AAG-----CPPGRVC------------------- 5219
S L+CQ AAG C G VC
Sbjct: 762 PKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECP 821
Query: 5220 ------------EVKAEARNCWATRG--LCVLSVGANLTTFDGARGATTSPG-VYELSSR 5264
++K + C RG +C +V + G+ T G Y+
Sbjct: 822 CVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGH 881
Query: 5265 CPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD---GMVTLTPNKGVWVNGLRVDLP 5321
C VA C G+ ++G I ++ G +T +K + + R +L
Sbjct: 882 C----------SYVAVQDYC-GQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELK 930
Query: 5322 AEKLASVSVSRTPDGS-----------LLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCG 5370
E V + R L+V G+ V V + ++ + G +CG
Sbjct: 931 LEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCG 990
Query: 5371 ACGNFDGDQTNDW 5383
CGNFD ND+
Sbjct: 991 LCGNFDHRSNNDF 1003
Score = 246 bits (627), Expect = 6e-64
Identities = 219/803 (27%), Positives = 314/803 (39%), Gaps = 92/803 (11%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
C + A G Q G VC G+ HY TFDG + G C Y C
Sbjct: 12 CLALSLAGGSELQTEGRTRN---HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR 68
Query: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEV----GFVLVDNQRSRL 559
+ F+V K + + V + + ++ LTR V + L
Sbjct: 69 --GSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL 126
Query: 560 PVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA 619
+ S+ +VY GL + ++ + L L L +F++ CGLCG+YNG +
Sbjct: 127 LIEKSDAYTKVYSRA---------GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQS 177
Query: 620 DDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLT 678
DG L +EF + K++ D +CED + PA C+ +A+ C L
Sbjct: 178 YSEFLSDGVLF-SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-------CERLL 229
Query: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738
+ FA C D + P+L C D C G +C ++ +++ C G G+WR+
Sbjct: 230 TAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTA 288
Query: 739 ANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVP 795
CP +CP N Y G C +C+ S C ++GC C G V CVP
Sbjct: 289 TLCPKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR-MDGCFCPEGTVYDDIGDSGCVP 347
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 855
S C C G PGQE+ D C+ +C CN + C+D CP
Sbjct: 348 VSQCHCRLHGHLYTPGQEITND--CE-QCVCNAG--RWVCKD-LPCP------------- 388
Query: 856 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 915
GTC G H +FDG+ + F G C Y+L N + L Q
Sbjct: 389 ------GTCALEGGSHITTFDGKTYTFHGDCYYVLAKG-DHNDSYALLGELAPCGSTDKQ 441
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFR-QGRDAVVRTD 974
T T + + + V + + G VL++++ LP A VFR +V
Sbjct: 442 TCLKTVVLLADKKKNVVVFKSD--GSVLLNELQVNLPHVTA--SFSVFRPSSYHIMVSMA 497
Query: 975 FGLTVTYDWNARVTAKVPSSYAE--ALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW 1032
G+ + + V A + GLCGNFNG DD G A F N+W
Sbjct: 498 IGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTW 557
Query: 1033 QEETRPGCGATEPGDCPKLDSLVAQQLQSKNE----CGILADPKGPFRECHSKLDPQGAV 1088
+ ++ C LD + ++S N C +L + PF CHS +DP
Sbjct: 558 KAQS--SC----HDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYY 611
Query: 1089 RDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPL---SCPPHSHYEAC 1145
+ C YD C LC AL++YA AC A G + WR E +C SCP +
Sbjct: 612 KRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYN 670
Query: 1146 SYGCPLSCGDLPVPGGCGSECHE------GCVC-DEGFALSGESCLPLASCGCVHQGTYH 1198
C +C L S C E GC C D F C+PLA C C H+G Y
Sbjct: 671 LTTCQQTCRSL---SEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYL 727
Query: 1199 PPGQTFYPGPGCDSLCHCQEGGL 1221
G + C C++G L
Sbjct: 728 EAGDVVVRQ---EERCVCRDGRL 747
Score = 222 bits (566), Expect = 7e-57
Identities = 227/815 (27%), Positives = 320/815 (39%), Gaps = 117/815 (14%)
Query: 1248 GSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 1307
G + C G+ HY TFDG F F G C Y A C R FAV ++ G G+
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
Query: 1308 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
I + + + T+ L + +NG + P I S + V GL
Sbjct: 88 PAGVESILLTIKDDTIYLTRHL--AVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
Query: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVP 1424
+ ++ + + + + CGLCG+YNG +G EFGN + P
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNMQKINQP 202
Query: 1425 DSPCLPPTPCPPGSEDCIPS----HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDP 1480
D C P E+ P+ H+ E E+ E F + C LV
Sbjct: 203 DVVCEDP------EEEVAPASCSEHRA--ECERLLTAEAF-----------ADCQDLVPL 243
Query: 1481 QGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYEL 1540
+ L+ C D C G + +CS + + C AGG WRT T CP CP N Y
Sbjct: 244 EPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLE 303
Query: 1541 CADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYN---GQACVPIQQCGCYHNGVYYEPE 1597
C CS L C++ +GC C G +Y+ CVP+ QC C +G Y P
Sbjct: 304 SGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPG 363
Query: 1598 QTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCK 1657
Q I N +QC C+AG+ VC++ C PG
Sbjct: 364 QE--ITNDCEQCVCNAGR-WVCKDLPC-PG------------------------------ 389
Query: 1658 EQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT-TGCPGVSTQG-LTPF 1715
TC L G H +FDG+ + F G C YVLA + G L P
Sbjct: 390 --------------TCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPC 435
Query: 1716 TVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVT 1775
T K VV +A N+ + K + G V +N + LP A SV
Sbjct: 436 GSTDKQ-------TCLKTVVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVF 485
Query: 1776 QGASKALLVA---DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT 1832
+ +S ++V+ LQV ++ VTL + G V GLCGN + +D +G
Sbjct: 486 RPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGL 545
Query: 1833 LAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTC 1892
+ + + +W+A C D+ C + +C L T PF C
Sbjct: 546 VEATGAGFANTWKA---QSSCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRC 601
Query: 1893 HAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---T 1949
H+ V P ++K C D C + D LC AL+SY AC A GV++ WR V C +
Sbjct: 602 HSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGS 660
Query: 1950 CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCG 2008
CP + + + C +C S + + + V+GC C D F+ RCVPL C
Sbjct: 661 CPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CS 719
Query: 2009 CWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVC 2043
C+ G Y EAG D Q RC G L C
Sbjct: 720 CYHRGLYLEAG-----DVVVRQEERCVCRDGRLHC 749
Score = 217 bits (552), Expect = 3e-55
Identities = 239/886 (26%), Positives = 337/886 (38%), Gaps = 127/886 (14%)
Query: 2449 GSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 2508
G C G+ HY TFDG F F G C Y A C R FAV ++ G G+
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
Query: 2509 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 2565
I + + + T+ L + +NG + P I S + V GL
Sbjct: 88 PAGVESILLTIKDDTIYLTRHL--AVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
Query: 2566 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVP 2625
+ ++ + + + + CGLCG+YNG +G EFGN + P
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNMQKINQP 202
Query: 2626 DSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPL 2685
D C P EE P +++ E C L + + C LV + L
Sbjct: 203 DVVCEDP------------EEEVAPASCSEHRAE--CERLLTAEA-FADCQDLVPLEPYL 247
Query: 2686 KDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADT 2745
+ C D C G + +CS + + C AGG+ WR T CP CP N Y
Sbjct: 248 RACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSP 307
Query: 2746 CSLGCSALSAPLQCPDGCAEGCQCDSGFLYNG---QACVPIQQCGCYHNGAYYEPEQTVL 2802
C CS L C + +GC C G +Y+ CVP+ QC C +G Y P Q +
Sbjct: 308 CMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYTPGQEIT 367
Query: 2803 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGG 2862
D C +QC C+ G+ V C++ C PG
Sbjct: 368 ND-C-EQCVCNAGRWV-CKDLPC-PG---------------------------------- 389
Query: 2863 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC-PGVSTQG-LTPFTVTT 2920
TC L G H +FDG+ + F G C YVLA + G L P T
Sbjct: 390 ----------TCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELAPCGSTD 439
Query: 2921 KNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 2980
K VV +A N+ + K + G V +N + LP A SV + +S
Sbjct: 440 KQ-------TCLKTVVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSS 489
Query: 2981 KALLVA---DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 3037
++V+ LQV ++ VTL + G V GLCGN + +D +G + +
Sbjct: 490 YHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEAT 549
Query: 3038 IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHV 3097
+ +W+A C D+ C + +C L T PF CH+ V
Sbjct: 550 GAGFANTWKAQS---SCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRCHSAV 605
Query: 3098 PPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPEN 3154
P ++K C D C + D LC AL+SY AC A GV++ WR V C +CP +
Sbjct: 606 DPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNS 664
Query: 3155 SHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWAN 3213
+ C +C S + + + V+GC C D F+ RCVPL C C+
Sbjct: 665 QVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHR 723
Query: 3214 GTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS---- 3269
G Y EAG D Q RC G L C +G+ C P C ++
Sbjct: 724 GLYLEAG-----DVVVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSNLTALAT 776
Query: 3270 ----TAECQAWGDPHY--------VTLDGHRFDFQGTCEYLLSAPC 3303
CQ +Y V DG D +G C PC
Sbjct: 777 SKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 822
Score = 216 bits (549), Expect = 6e-55
Identities = 239/892 (26%), Positives = 335/892 (37%), Gaps = 139/892 (15%)
Query: 3650 GSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 3709
G C G+ HY TFDG F F G C Y A C R FAV ++ G G+
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
Query: 3710 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 3766
I + + + T+ L + +NG + P I S + V GL
Sbjct: 88 PAGVESILLTIKDDTIYLTRHL--AVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
Query: 3767 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVP 3826
+ ++ + + + + CGLCG+YNG +G EFGN + P
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPL-EFGNMQKINQP 202
Query: 3827 DSPC------LPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLV 3880
D C + P +C A C E+ E F + C LV
Sbjct: 203 DVVCEDPEEEVAPASCSEHRAEC----------ERLLTAEAF-----------ADCQDLV 241
Query: 3881 DPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHY 3940
+ L+ C D C G + +CS + + C AGG WR T CP CP N Y
Sbjct: 242 PLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVY 301
Query: 3941 ELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNG---QACVPIQQCGCYHNGVYYE 3997
C CS L C + +GC C G +Y+ CVP+ QC C +G Y
Sbjct: 302 LESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQCHCRLHGHLYT 361
Query: 3998 PEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057
P Q + D C +QC C+ G+ V C++ C PG
Sbjct: 362 PGQEITND-C-EQCVCNAGRWV-CKDLPC-PG---------------------------- 389
Query: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGC-PGVSTQG-LT 4115
TC L G H +FDG+ + F G C YVLA + G L
Sbjct: 390 ----------------TCALEGGSHITTFDGKTYTFHGDCYYVLAKGDHNDSYALLGELA 433
Query: 4116 PFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRIS 4175
P T K VV +A N+ + K + G V +N + LP A S
Sbjct: 434 PCGSTDKQ-------TCLKTVVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FS 483
Query: 4176 VAQGASKALLVA---DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPN 4232
V + +S ++V+ LQV ++ VTL + G V GLCGN + +D +
Sbjct: 484 VFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTAS 543
Query: 4233 GTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFT 4292
G + + + +W+A C D+ C + +C L T PF
Sbjct: 544 GLVEATGAGFANTWKAQS---SCHDKLDWLDDPCSLNIESANYAEHWCSLLKK-TETPFG 599
Query: 4293 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-- 4350
CH+ V P ++K C D C + D LC AL+SY AC A GV++ WR V C
Sbjct: 600 RCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDV 658
Query: 4351 -TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNG 4408
+CP + + C +C S + + + V+GC C D F+ RCVPL
Sbjct: 659 GSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK- 717
Query: 4409 CGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQP 4468
C C+ G Y EAG D Q RC G L C +G+ C P C
Sbjct: 718 CSCYHRGLYLEAG-----DVVVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSN 770
Query: 4469 VS--------TAECQAWGDPHY--------VTLDGHRFDFQGTCEYLLSAPC 4504
++ CQ +Y V DG D +G C PC
Sbjct: 771 LTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 822
Score = 199 bits (506), Expect = 6e-50
Identities = 199/772 (25%), Positives = 295/772 (38%), Gaps = 87/772 (11%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WG+ HY +FDG F F G C+Y A+ C G + F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASD-CRGSYKE----FAVHLKRGPGQAEAPAGV 91
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVTQGASKALLVADFGLQ 1790
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 1851 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 1909
+C D P +C E R E C L T F C VP E + + C D
Sbjct: 204 VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
Query: 1910 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPS 1969
C G +C +A + C AG +WR C TCP N Y GSPC +C
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC-- 312
Query: 1970 PAPLTTPAVCEGPCVEGCQCDAGFV---LSADRCVPLNNGCGCWANGTYHEAGSEFWADG 2026
+ L ++CE ++GC C G V + CVP++ C C +G + G E D
Sbjct: 313 -SHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQ-CHCRLHGHLYTPGQEITND- 369
Query: 2027 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 2086
C Q C C G VC C C G H T DG
Sbjct: 370 -CEQ-CVC--NAGRWVCKDLPC--------------------PGTCALEGGSHITTFDGK 405
Query: 2087 RFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTLQIYNHSLTLSA 2145
+ F G C Y+L+ H +++ + GS + ++V L +
Sbjct: 406 TYTFHGDCYYVLAKGDHN-----DSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVF 460
Query: 2146 RWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV--PAAY 2203
+ + ++ + V LP S S ++V+ G+ L ++L V A
Sbjct: 461 KSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQAS 520
Query: 2204 AGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQE 2258
G + GLCGN+N DD K G G A + C K PC+ +
Sbjct: 521 QGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIES 580
Query: 2259 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 2318
+ C ++ T+ P CH V PA+Y++ C D C Q + LC A+++Y AC
Sbjct: 581 ANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACT 640
Query: 2319 AAGAQLREWRRPDFC---PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE------ 2369
A G L WR C CP + +C +C SLS +S C E
Sbjct: 641 AKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVD 696
Query: 2370 GCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 2420
GC C D F+ CVP+ +C C H Y G + C CR+G
Sbjct: 697 GCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDG 745
Score = 197 bits (500), Expect = 3e-49
Identities = 198/772 (25%), Positives = 294/772 (38%), Gaps = 87/772 (11%)
Query: 2874 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 2933
C WG+ HY +FDG F F G C+Y A+ C G + F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASD-CRGSYKE----FAVHLKRGPGQAEAPAGV 91
Query: 2934 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVTQGASKALLVADFGLQ 2991
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 3052 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110
+C D P +C E R E C L T F C VP E + + C D
Sbjct: 204 VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
Query: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPS 3170
C G +C +A + C AG +WR C TCP N Y G PC +C
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATLCPKTCPGNLVYLESGSPCMDTC-- 312
Query: 3171 PAPLTTPAVCEGPCVEGCQCDAGFV---LSADRCVPLNNGCGCWANGTYHEAGSEFWADG 3227
+ L ++CE ++GC C G V + CVP++ C C +G + G E D
Sbjct: 313 -SHLEVSSLCEEHRMDGCFCPEGTVYDDIGDSGCVPVSQ-CHCRLHGHLYTPGQEITND- 369
Query: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGH 3287
C Q C C G VC C C G H T DG
Sbjct: 370 -CEQ-CVC--NAGRWVCKDLPC--------------------PGTCALEGGSHITTFDGK 405
Query: 3288 RFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTLQIYNHSLTLSA 3346
+ F G C Y+L+ H +++ + GS + ++V L +
Sbjct: 406 TYTFHGDCYYVLAKGDHN-----DSYALLGELAPCGSTDKQTCLKTVVLLADKKKNVVVF 460
Query: 3347 RWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV--PAAY 3404
+ + ++ + V LP S S ++V+ G+ L ++L V A
Sbjct: 461 KSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQAS 520
Query: 3405 AGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQE 3459
G + GLCGN+N DD K G G A + C K PC+ +
Sbjct: 521 QGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIES 580
Query: 3460 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 3519
+ C ++ T+ P CH V PA+Y++ C D C Q + LC A+++Y AC
Sbjct: 581 ANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACT 640
Query: 3520 AAGAQLREWRRPDFC---PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE------ 3570
A G L WR C CP + +C +C SLS +S C E
Sbjct: 641 AKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVD 696
Query: 3571 GCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 3621
GC C D F+ CVP+ +C C H Y G + C CR+G
Sbjct: 697 GCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDG 745
Score = 180 bits (456), Expect = 4e-44
Identities = 137/466 (29%), Positives = 206/466 (44%), Gaps = 57/466 (12%)
Query: 776 CVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVT 834
CV GCVC G + G G CV C C + G ++ D CN T
Sbjct: 796 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--------CN------T 841
Query: 835 CRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS- 893
C +C G Q C+ GTC G HY++FDG+ +DF G C+Y+ V
Sbjct: 842 C----TCKRGRWVCTQ---AVCH----GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 890
Query: 894 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953
CGQN++L +F ++ EN G+ V+ ++A+++ ++ + ++ V+ D ++ +
Sbjct: 891 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR-VVIQRDEGHHVAY 949
Query: 954 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013
+ G+ VV + G+ V +D V K+ SY +CGLCGNF+ +D
Sbjct: 950 TTRE-------VGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 1002
Query: 1014 LALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKG 1073
R ++ L FGNSW+E +T P C ++ ++ +C IL
Sbjct: 1003 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH---RRSWAEKQCSIL--KSS 1057
Query: 1074 PFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEEL 1131
F CHSK+DP+ CV+D C G C A+A+YA C GA V WR+ +L
Sbjct: 1058 VFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDL 1116
Query: 1132 CPLSC----PPHS---HYEACSYGCPLSCGDL-PVPGGCGSECHEGCV--CDEGFALSGE 1181
CP+ C PPH HYE C +C + + EGC C + + E
Sbjct: 1117 CPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEE 1176
Query: 1182 ---SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
C+ CGC + T++PPG + C S C C V C
Sbjct: 1177 DLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVC 1221
Score = 177 bits (448), Expect = 3e-43
Identities = 156/597 (26%), Positives = 228/597 (38%), Gaps = 102/597 (17%)
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSG-DTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
SC +L+A + C GCVC G + G CV +C C+H++ Y G C
Sbjct: 783 SCQTLAAGY-YHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--C 839
Query: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDF 2471
++ C C+ G V + AV TC G HY TFDG+ +DF
Sbjct: 840 NT-CTCKRGRWVCTQ--------------------AVCHGTCSIYGSGHYITFDGKYYDF 878
Query: 2472 MGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV 2530
G C YV Q CG L F+++ ENV G V+ ++ I + + L+LE + V
Sbjct: 879 DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 938
Query: 2531 TVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGL 2590
D V ++ G +V+E+ G+ V +D V + + +Y +CGL
Sbjct: 939 IQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGL 991
Query: 2591 CGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPP 2650
CGN++ +DF + + +FGNSW+E PTCP S E C
Sbjct: 992 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---------PTCPDVSTN---PEPCSL 1039
Query: 2651 ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHA 2708
++ E+ C +L S S CH VDP+ + C+ D C GG+ CS + +
Sbjct: 1040 NPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVAS 1097
Query: 2709 YVSACQAAGGQVEPWRNETFCPMECPQNS-------HYELCADTCSLGCSALSA-----P 2756
Y C G V WR CP+ C + HYE C + C ++
Sbjct: 1098 YAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1156
Query: 2757 LQCPDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVG 2815
+ +GC C D + CV +CGCY +Y P +V + + C C
Sbjct: 1157 VSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNS 1216
Query: 2816 KVVVCQEHSCK-----------PGQVCQPSGGILSCVNKDPCHGVTCRPQ---------- 2854
VVC+ K ++C P+G + N +T RP
Sbjct: 1217 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFN---ICSITTRPSTLTTFTTITL 1273
Query: 2855 ---------ETCKEQGGQGVCLPNYEATCWLWGD------PHYHSFDGRKFDFQGTC 2896
T L C LW D P S DG + F G C
Sbjct: 1274 PTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVC 1330
Score = 176 bits (447), Expect = 4e-43
Identities = 173/675 (25%), Positives = 248/675 (36%), Gaps = 105/675 (15%)
Query: 1079 HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP- 1137
H+ LD +G C G D + C +H R L SC
Sbjct: 703 HTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLH-CRQIRLIGQSCTA 761
Query: 1138 PHSHYE-------ACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGES-CLPLASC 1189
P H + A S LSC L G +EC GCVC +G G C+ C
Sbjct: 762 PKIHMDCSNLTALATSKPRALSCQTLAA-GYYHTECVSGCVCPDGLMDDGRGGCVVEKEC 820
Query: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGS 1249
CVH + G C++ C C+ G V + AV
Sbjct: 821 PCVHNNDLYSSGAKIKVD--CNT-CTCKRGRWVCTQ--------------------AVCH 857
Query: 1250 STCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVT 1308
TC G HY TFDG+ +DF G C YV Q CG L F+++ ENV G V+ +
Sbjct: 858 GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCS 917
Query: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY 1368
+ I + + L+LE + V D V ++ G +V+E+ G+ V +
Sbjct: 918 KAIKIFMGRTELKLEDKHRVVIQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIW 970
Query: 1369 DLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 1428
D V + + +Y +CGLCGN++ +DF + + +FGNSW+E P P
Sbjct: 971 DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPD 1029
Query: 1429 LPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 1488
+ P P C ++ E+ C +L S S CH VDP+ + C+
Sbjct: 1030 VSTNPEP-----------CSLNPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACV 1076
Query: 1489 FDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC----PPNS---HYE 1539
D C GG+ CS + +Y C G V WRT CP+ C PP+ HYE
Sbjct: 1077 HDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYE 1135
Query: 1540 LCADTCSLGCSALSA-----PPQCQDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVY 1593
C + C ++ +GC C D + CV +CGCY +
Sbjct: 1136 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH 1195
Query: 1594 YEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCK-----------PGQVCQPSGGI-----L 1637
Y P +V + + C C +VC+ K ++C P+G + +
Sbjct: 1196 YPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNI 1255
Query: 1638 SCVTKDPCHGVTCR-----------PQETCKEQGGQGVCLPNYEATCWLWGD------PH 1680
+T P T T L C LW D P
Sbjct: 1256 CSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPS 1315
Query: 1681 YHSFDGRKFDFQGTC 1695
S DG + F G C
Sbjct: 1316 SGSDDGDRETFDGVC 1330
Score = 174 bits (441), Expect = 2e-42
Identities = 155/594 (26%), Positives = 227/594 (38%), Gaps = 96/594 (16%)
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSG-DTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 3612
SC +L+A + C GCVC G + G CV +C C+H++ Y G C
Sbjct: 783 SCQTLAAGY-YHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--C 839
Query: 3613 DSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDF 3672
++ C C+ G V + AV TC G HY TFDG +DF
Sbjct: 840 NT-CTCKRGRWVCTQ--------------------AVCHGTCSIYGSGHYITFDGKYYDF 878
Query: 3673 MGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV 3731
G C YV Q CG L F+++ ENV G V+ ++ I + + L+LE + V
Sbjct: 879 DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 938
Query: 3732 TVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGL 3791
D V ++ G +V+E+ G+ V +D V + + +Y +CGL
Sbjct: 939 IQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGL 991
Query: 3792 CGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPP 3851
CGN++ +DF + + +FGNSW+E PTCP S P C
Sbjct: 992 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---------PTCPDVSTNPEP---CSL 1039
Query: 3852 ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHA 3909
++ E+ C +L S S CH VDP+ + C+ D C GG+ CS + +
Sbjct: 1040 NPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVAS 1097
Query: 3910 YVSACQAAGGHVEPWRNETFCPMECPQNS-------HYELCADTCSLGCSALSA-----P 3957
Y C G V WR CP+ C + HYE C + C ++
Sbjct: 1098 YAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1156
Query: 3958 LQCPDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVG 4016
+ +GC C D + CV +CGCY +Y P +V + + C C
Sbjct: 1157 VSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNS 1216
Query: 4017 KVVVCQEHSCK-----------PGQVCQPSGGI-----LSCVTKDPCHGVTCR------- 4053
VVC+ K ++C P+G + + +T P T
Sbjct: 1217 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTT 1276
Query: 4054 ----PQETCKEQGGQGVCLPNYEATCWLWGD------PHYHSFDGRKFDFQGTC 4097
T L C LW D P S DG + F G C
Sbjct: 1277 PTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVC 1330
Score = 160 bits (404), Expect = 4e-38
Identities = 118/404 (29%), Positives = 178/404 (44%), Gaps = 39/404 (9%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFS 512
C G+ C A C G HY TFDG+ YD G CSY V+ C ++ +L +FS
Sbjct: 842 CTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS 901
Query: 513 VEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
+ +N G+ V+ S ++ + G L D + R+ + EG Y
Sbjct: 902 IITENVPCGTTGVTC---------SKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYT 950
Query: 573 S---GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGAL 629
+ G VVE G++V +D + + L ++ VCGLCGN++ +DF T D +
Sbjct: 951 TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMV 1010
Query: 630 APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
++F +SWK C D N P C+ + ++ C +L F++CH
Sbjct: 1011 VSSELDFGNSWKEAP---TCPDVSTNPEP-CSLNPHRRSWAEKQCSILK--SSVFSICHS 1064
Query: 690 TLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-- 745
+DP+PF E CV+D C GG+ C +++YAQ C + G V WR+P CP+ C
Sbjct: 1065 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDY 1123
Query: 746 -----PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCV--C---LPGFVASGGACVP 795
YE CG +C + +EGC C P + CV
Sbjct: 1124 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1183
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 839
A CGC + PG V +E C + C C ++ QV CR ++
Sbjct: 1184 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSS-QVVCRPEE 1225
Score = 144 bits (364), Expect = 2e-33
Identities = 119/469 (25%), Positives = 188/469 (40%), Gaps = 65/469 (13%)
Query: 3184 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 3243
CV GC C G + + C C N + +G++ D C+ C C G V
Sbjct: 796 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWV 850
Query: 3244 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 3303
CT A C HG C +G HY+T DG +DF G C Y+
Sbjct: 851 CTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 890
Query: 3304 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVTLP 3362
G +F++ N G+ V+ ++++ + + L L + +Q D G V
Sbjct: 891 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT 950
Query: 3363 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADD 3422
G +VV +++G+ + +D + V +++ +Y G++CGLCGN++ +D
Sbjct: 951 --------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 1002
Query: 3423 LKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLA 3478
++ E + P P PC+ C ++ ++ +
Sbjct: 1003 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFS 1060
Query: 3479 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPF 3536
CH V P +++ C+ D+C G C AVA+Y C GA + WR PD CP
Sbjct: 1061 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPI 1119
Query: 3537 QC----PAHS---HYELCGDSCPGSCP---------SLSAPEGCESAC-REGCVCDAGFV 3579
C P H HYE CG+ +C S+S EGC C ++ + +
Sbjct: 1120 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL- 1178
Query: 3580 LSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEP 3628
CV +CGC +D +YP G + C S C C +V C P
Sbjct: 1179 ---KKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1223
Score = 143 bits (361), Expect = 4e-33
Identities = 126/512 (24%), Positives = 203/512 (39%), Gaps = 71/512 (13%)
Query: 1944 VGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG----PCVEGCQCDAGFVLSADR 1999
+G T P+ H + C + + P L+ + G CV GC C G +
Sbjct: 755 IGQSCTAPK-IHMD-CSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRG 812
Query: 2000 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 2059
+ C C N + +G++ D C+ C C G VCT A C
Sbjct: 813 GCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWVCTQAVC----------- 856
Query: 2060 GQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANE 2119
HG C +G HY+T DG ++F G C Y+ G +F++ N
Sbjct: 857 --HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENV 907
Query: 2120 HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVTLPFQLDSLLHAHLSGADVV 2178
G+ V+ ++++ + + L L + +Q D G V G +V
Sbjct: 908 PCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT--------TREVGQYLV 959
Query: 2179 VTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ 2238
V +++G+ + +D + V +++ +Y G++CGLCGN++ +D ++
Sbjct: 960 VESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGN 1019
Query: 2239 GCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL 2294
E + P P PC+ C ++ ++ + CH V P +++ C+
Sbjct: 1020 SWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFSICHSKVDPKPFYEACVH 1077
Query: 2295 DACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQC----PAHS---HYEL 2345
D+C G C AVA+Y C GA + WR PD CP C P H HYE
Sbjct: 1078 DSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEP 1136
Query: 2346 CGDSCPGSCP---------SLSAPEGCESAC-REGCVCDAGFVLSGDTCVPVGQCGCLHD 2395
CG+ +C S+S EGC C ++ + + CV +CGC +
Sbjct: 1137 CGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL----KKCVTADKCGCYVE 1192
Query: 2396 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEP 2427
D +YP G + C S C C +V C P
Sbjct: 1193 DTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1223
Score = 141 bits (356), Expect = 2e-32
Identities = 122/393 (31%), Positives = 177/393 (45%), Gaps = 43/393 (10%)
Query: 472 CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS--RRVSYVG 529
C +G H TTFDG+ Y G C Y + ++ D ++++ + GS ++
Sbjct: 391 CALEGGSHITTFDGKTYTFHGDCYYVL----AKGDHNDSYALLGELAPCGSTDKQTCLKT 446
Query: 530 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP-VSLSEGRLRVYQSGPRAVVELVFG--LV 586
+V + +V + + + G VL++ + LP V+ S R S +V + G L
Sbjct: 447 VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTASFSVFR--PSSYHIMVSMAIGVRLQ 503
Query: 587 VTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL---- 642
V QL ++L Q QV GLCGN+NG DDF T G + FA++WK
Sbjct: 504 VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSC 563
Query: 643 -DDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCV 701
D D+L +D C N + A+H+ C +L K + PF CH +DP + ++C
Sbjct: 564 HDKLDWL-DDPCSLNIESAN--YAEHW-----CSLLKKTETPFGRCHSAVDPAEYYKRCK 615
Query: 702 YDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL---SCPANSRYELCGPAC 758
YD C LC LS+YA+AC G+ + WR C SCP + + C
Sbjct: 616 YDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTC 674
Query: 759 PTSCNG-AAAPSNC-SGRPCVEGCVCLP-GFVASGGACVPASSCGCTFQGLQLAPGQEVW 815
+C + A S+C G V+GC C F+ G CVP + C C +GL L G V
Sbjct: 675 QQTCRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV 734
Query: 816 ADELCQRRCTC-NGATHQVTCRD----KQSCPA 843
E RC C +G H CR QSC A
Sbjct: 735 RQE---ERCVCRDGRLH---CRQIRLIGQSCTA 761
Score = 139 bits (350), Expect = 8e-32
Identities = 121/484 (25%), Positives = 191/484 (39%), Gaps = 76/484 (15%)
Query: 4385 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 4444
CV GC C G + + C C N + +G++ D C+ C C G V
Sbjct: 796 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWV 850
Query: 4445 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 4504
CT A C HG C +G HY+T DG +DF G C Y+
Sbjct: 851 CTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 890
Query: 4505 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVALP 4563
G +F++ N G+ V+ ++++ + + L L + +Q D G VA
Sbjct: 891 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT 950
Query: 4564 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 4623
G +VV +++G+ + +D + V +++ +Y ++CGLCGN++ +D
Sbjct: 951 --------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 1002
Query: 4624 LKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLA 4679
++ E + P P PC+ C ++ ++ +
Sbjct: 1003 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFS 1060
Query: 4680 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL 4737
CH V P +++ C+ D+C G C AVA+Y C GA + WR PD CP+
Sbjct: 1061 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPI 1119
Query: 4738 QC----PAHS---HYELCGDSCPVSCP---------SLSAPEGCESAC-REGCVCDAGFV 4780
C P H HYE CG+ +C S+S EGC C ++ + +
Sbjct: 1120 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL- 1178
Query: 4781 LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC-----------QE 4829
CV +CGC + +YP G P E + C C V C Q+
Sbjct: 1179 ---KKCVTADKCGCYVEDTHYPPG-ASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQD 1234
Query: 4830 GAAC 4833
GA C
Sbjct: 1235 GAFC 1238
Score = 138 bits (348), Expect = 1e-31
Identities = 126/429 (29%), Positives = 188/429 (43%), Gaps = 37/429 (8%)
Query: 449 CAAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDD 506
C+ G + V GC E C GDPHY TFDG Y G C+Y +VE S
Sbjct: 4456 CSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--P 4513
Query: 507 TLPAFSVEAKNEH-RGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSE 565
++ F V N H + +VS + VR + V + + + V Q +R V+L
Sbjct: 4514 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 4573
Query: 566 GR--LRVYQSGPRAVVEL-VFGLVVTYDWDCQLALSLP-ARFQDQVCGLCGNYNGDPADD 621
+ L VYQSG VV++ G++V+Y+ ++ LP RF + G CG +DD
Sbjct: 4574 KKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 4632
Query: 622 FLTPDGALAPDAVEFASSWKLDDGD--YLCEDGCQNNCPACT-PGQAQ---HYE--GDRL 673
+ P G + + A W ++D + PA T PG + H + L
Sbjct: 4633 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 4692
Query: 674 CGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVG 733
C ++ D FA CH + P+ + + CV+D C + G L C L AYA C + I +
Sbjct: 4693 CQLIK--DSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICL- 4748
Query: 734 DWRSPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV-ASG 790
DWR+ + C + CP++ Y+ CGPA +C +++ N VEGC C G + +
Sbjct: 4749 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN--NTVLVEGCFCPEGTMNYAP 4806
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G V +CGC G P + E + C C + C+ K RCS Q
Sbjct: 4807 GFDVCVKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPK-------RCS-Q 4856
Query: 851 NGLLGCYPD 859
+ C D
Sbjct: 4857 KPVTHCVED 4865
Score = 132 bits (331), Expect = 1e-29
Identities = 128/486 (26%), Positives = 182/486 (37%), Gaps = 66/486 (13%)
Query: 4012 TCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNY 4071
TC V + C+P + S G+ +DP G C ++
Sbjct: 4434 TCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDP-----------------DGCCW-HW 4475
Query: 4072 EATCWL--WGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTV-TTKNQNRGN 4128
E C+ WGDPHY +FDG + +QG C YVL P V G+ N
Sbjct: 4476 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 4535
Query: 4129 PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVAD 4188
P VR T L + + ++ +V+VN ALP G G + + + +
Sbjct: 4536 PRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAVALPYK-KYGLEVYQSGINYVVDIPE 4593
Query: 4189 FGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 4245
G+ VSY+ V LP YH G CG ++D + P+G + +
Sbjct: 4594 LGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 4650
Query: 4246 WRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGPGFCGPLSSGTGGP---------FTT 4293
W L D + CP + + G G P T P F
Sbjct: 4651 W-------LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQ 4703
Query: 4294 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV--GCEIT 4351
CHA VPP+ ++ CV D C G + C +L +Y A C + + DWR C +
Sbjct: 4704 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQNICL-DWRNHTHGACLVE 4761
Query: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG---FVLSADRCVPLNNG 4408
CP + Y+ CGP +C S + V VEGC C G + D CV
Sbjct: 4762 CPSHREYQACGPAEEPTCKSSSSQQNNTV----LVEGCFCPEGTMNYAPGFDVCV---KT 4814
Query: 4409 CGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 4467
CGC + E G F D C C C GG ++C P C V + G +
Sbjct: 4815 CGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 4871
Query: 4468 PVSTAE 4473
V+ A+
Sbjct: 4872 EVNPAD 4877
Score = 130 bits (327), Expect = 4e-29
Identities = 123/451 (27%), Positives = 172/451 (38%), Gaps = 56/451 (12%)
Query: 2853 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 2903
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 4452 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 4510
Query: 2904 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
P V G+ N P VR T L + + ++ +V+VN
Sbjct: 4511 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 4569
Query: 2963 ALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 3019
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 4570 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 4625
Query: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGP 3076
++D + P+G + + W L D + CP + + G
Sbjct: 4626 TNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVPGG 4678
Query: 3077 GFCGPLAPGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASY 3127
G P T P F CHA VPP+ ++ CV D C G + C +L +Y
Sbjct: 4679 GKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAY 4737
Query: 3128 VAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCV 3185
A C + + DWR C + CP + Y+ CGP +C S + V V
Sbjct: 4738 AALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LV 4792
Query: 3186 EGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGS 3241
EGC C G + D CV CGC + E G F D C C C GG
Sbjct: 4793 EGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSG 4846
Query: 3242 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 3272
++C P C V + G + V+ A+
Sbjct: 4847 IICQPKRCSQKPVTHCVEDGTYLATEVNPAD 4877
Score = 128 bits (322), Expect = 1e-28
Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 1310
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 4538
Query: 1311 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 1364
+ T +V T+ + Q +V VN + LP + Q G + V++ + G+
Sbjct: 4539 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 4596
Query: 1365 RVAYD-LVYYVRVTVP--GNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 1421
V+Y+ L + VR+ GN + CG C N DD P+G N + W
Sbjct: 4597 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 4653
Query: 1422 VVPDSPCLP--------PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
P P P P PG P C P C L+ +
Sbjct: 4654 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 4703
Query: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF--CPME 1531
CH LV PQ C+FD C G+ S+ C+++ AY + C A WR T C +E
Sbjct: 4704 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 4761
Query: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 1589
CP + Y+ C C + S+ Q EGC C G + Y V ++ CGC
Sbjct: 4762 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 4820
Query: 1590 NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 1645
+ V E + D C+ G G++CQ C KP C G L+ D C
Sbjct: 4821 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879
Query: 1646 HGVTCRPQET--CKEQGGQGVCLPNYE 1670
+T T CKE+ VC +E
Sbjct: 4880 CNITVCKCNTSLCKEK--PSVCPLGFE 4904
Score = 127 bits (319), Expect = 3e-28
Identities = 122/451 (27%), Positives = 171/451 (37%), Gaps = 56/451 (12%)
Query: 1652 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 1702
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 4452 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 4510
Query: 1703 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761
P V G+ N P VR T L + + ++ +V+VN
Sbjct: 4511 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 4569
Query: 1762 ALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 1818
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 4570 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 4625
Query: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGP 1875
++D + P+G + + W L D + CP + + G
Sbjct: 4626 TNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVPGG 4678
Query: 1876 GFCGPLAPGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASY 1926
G P T P F CHA VPP+ ++ CV D C G + C +L +Y
Sbjct: 4679 GKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAY 4737
Query: 1927 VAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCV 1984
A C + + DWR C + CP + Y+ CG +C S + V V
Sbjct: 4738 AALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LV 4792
Query: 1985 EGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGS 2040
EGC C G + D CV CGC + E G F D C C C GG
Sbjct: 4793 EGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSG 4846
Query: 2041 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 2071
++C P C V + G + V+ A+
Sbjct: 4847 IICQPKRCSQKPVTHCVEDGTYLATEVNPAD 4877
Score = 127 bits (318), Expect = 4e-28
Identities = 126/446 (28%), Positives = 178/446 (39%), Gaps = 49/446 (10%)
Query: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 2511
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 4538
Query: 2512 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 2565
+ T +V T+ + Q +V VN + LP + Q G + V++ + G+
Sbjct: 4539 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 4596
Query: 2566 RVAYD-LVYYVRVTVP--GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 2622
V+Y+ L + VR+ GN + CG C N DD P+G N + W
Sbjct: 4597 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 4653
Query: 2623 VVPDSPCLP--------PPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSS 2674
P P P P PG P ++C P C L+ +
Sbjct: 4654 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 4703
Query: 2675 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETF--CPME 2732
CH LV PQ C+FD C G+ S+ C+++ AY + C A WRN T C +E
Sbjct: 4704 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 4761
Query: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCYHN 2791
CP + Y+ C C + S+ Q EGC C G + Y V ++ CGC
Sbjct: 4762 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 4820
Query: 2792 GAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGILSC-VN-KDPCH 2847
+C+ G ++CQ C KP C G L+ VN D C
Sbjct: 4821 DNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCC 4880
Query: 2848 GVTCRPQET--CKEQGGQGVCLPNYE 2871
+T T CKE+ VC +E
Sbjct: 4881 NITVCKCNTSLCKEK--PSVCPLGFE 4904
Score = 125 bits (315), Expect = 9e-28
Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 3712
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 4538
Query: 3713 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 3766
+ T +V T+ + Q +V VN + LP + Q G + V++ + G+
Sbjct: 4539 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 4596
Query: 3767 RVAYD-LVYYVRVTVP--GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 3823
V+Y+ L + VR+ GN + CG C N DD P+G N + W
Sbjct: 4597 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 4653
Query: 3824 VVPDSPCLP--------PPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSS 3875
P P P P PG P C P C L+ +
Sbjct: 4654 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 4703
Query: 3876 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETF--CPME 3933
CH LV PQ C+FD C G+ S+ C+++ AY + C A WRN T C +E
Sbjct: 4704 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 4761
Query: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 3991
CP + Y+ C C + S+ Q EGC C G + Y V ++ CGC
Sbjct: 4762 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 4820
Query: 3992 NGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 4047
+ V E + D C+ G ++CQ C KP C G L+ D C
Sbjct: 4821 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879
Query: 4048 HGVTCRPQET--CKEQGGQGVCLPNYE 4072
+T T CKE+ VC +E
Sbjct: 4880 CNITVCKCNTSLCKEK--PSVCPLGFE 4904
Score = 125 bits (314), Expect = 1e-27
Identities = 113/425 (26%), Positives = 166/425 (39%), Gaps = 42/425 (9%)
Query: 4816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDL 4874
+ EC P TC G + R+ED C C C G HY+T DG Y
Sbjct: 4445 KVECEPPPMPTCSNGL-----QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSY 4499
Query: 4875 HGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGDLQRLLV-------TVAGQVVSLA 4922
G+C+YVL + P ++F + ++ N R L+ + V +
Sbjct: 4500 QGNCTYVLVE--EISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMP 4557
Query: 4923 QGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSP---F 4978
QV V+ +AVALP + V G N V+ + G+ + ++G L S+ P F
Sbjct: 4558 MQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNG---LSFSVRLPYHRF 4614
Query: 4979 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCGEGCGPQGCPVCL 5037
G CG SDD +LP+G S+ E W SK C P
Sbjct: 4615 GNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVT 4674
Query: 5038 AE---ETAPYES---NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 5091
+T P++ + C +++ FA C A++ P Y+ CV+D C G + C
Sbjct: 4675 VPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPG-SSLEC 4731
Query: 5092 RSLAAYTAACQAAGVAVKPWR--TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 5149
SL AY A C + + WR T C + CP+H Y C + +C + S T
Sbjct: 4732 ASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NT 4789
Query: 5150 RCFEGCECDDRFL-LSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 5208
EGC C + + + G + V+ CGC DC SG+ C
Sbjct: 4790 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 4849
Query: 5209 QAAGC 5213
Q C
Sbjct: 4850 QPKRC 4854
Score = 124 bits (311), Expect = 3e-27
Identities = 122/442 (27%), Positives = 183/442 (41%), Gaps = 60/442 (13%)
Query: 2057 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCH 2103
+P+ +G QPV + C WGDPHYVT DG +++QG C Y+L
Sbjct: 4453 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 4512
Query: 2104 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 2158
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 4513 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 4569
Query: 2159 TLPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVPAAYAGS----LCGLCGN 2213
LP++ L + SG + VV G+ ++++G SF +R+P G+ CG C N
Sbjct: 4570 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 4627
Query: 2214 YNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVI 2269
D D + G + + Q SKP CP + ++ + GG
Sbjct: 4628 TTSD--DCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHK 4685
Query: 2270 SATDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 2320
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 4686 DCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQ 4744
Query: 2321 GAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG-- 2376
L +WR C +CP+H Y+ CG + +C S S+ + + EGC C G
Sbjct: 4745 NICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTM 4802
Query: 2377 -FVLSGDTCVPVGQCGCLHDDRY-YPLGQTFYPGPGCDSLCRCREGGE-VSCEPSSCG-- 2431
+ D CV CGC+ D G+ F C + C C EGG + C+P C
Sbjct: 4803 NYAPGFDVCVKT--CGCVGPDNVPREFGEHF--EFDCKN-CVCLEGGSGIICQPKRCSQK 4857
Query: 2432 PHETCRPSGGSLGCVAVGSTTC 2453
P C G L + TC
Sbjct: 4858 PVTHCVEDGTYLATEVNPADTC 4879
Score = 124 bits (310), Expect = 3e-27
Identities = 122/442 (27%), Positives = 182/442 (41%), Gaps = 60/442 (13%)
Query: 3258 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 3304
+P+ +G QPV + C WGDPHYVT DG + +QG C Y+L
Sbjct: 4453 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 4512
Query: 3305 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 3359
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 4513 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 4569
Query: 3360 TLPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVPAAYAGS----LCGLCGN 3414
LP++ L + SG + VV G+ ++++G SF +R+P G+ CG C N
Sbjct: 4570 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 4627
Query: 3415 YNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVI 3470
D D + G + + Q SKP CP + ++ + GG
Sbjct: 4628 TTSD--DCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHK 4685
Query: 3471 SATDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 3521
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 4686 DCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQ 4744
Query: 3522 GAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG-- 3577
L +WR C +CP+H Y+ CG + +C S S+ + + EGC C G
Sbjct: 4745 NICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTM 4802
Query: 3578 -FVLSGDTCVPVGQCGCLHDDRY-YPLGQTFYPGPGCDSLCRCREGGE-VSCEPSSCG-- 3632
+ D CV CGC+ D G+ F C + C C EGG + C+P C
Sbjct: 4803 NYAPGFDVCVKT--CGCVGPDNVPREFGEHF--EFDCKN-CVCLEGGSGIICQPKRCSQK 4857
Query: 3633 PHETCRPSGGSLGCVAVGSTTC 3654
P C G L + TC
Sbjct: 4858 PVTHCVEDGTYLATEVNPADTC 4879
Score = 119 bits (297), Expect = 1e-25
Identities = 121/456 (26%), Positives = 178/456 (39%), Gaps = 59/456 (12%)
Query: 825 TCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMG 884
TC+ V D C C CY C G GDPHYV+FDG + + G
Sbjct: 4455 TCSNGLQPVRVEDPDGCCWHWECD-------CY------CTGWGDPHYVTFDGLYYSYQG 4501
Query: 885 TCTYLLVGSCGQNAALPAFRVLVENEH---RGSQTVSYTRAVRVEARGVKVAVRREYPGQ 941
CTY+LV + ++ F V ++N H + T VR E + V + P Q
Sbjct: 4502 NCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ 4559
Query: 942 VLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVP-SSYAEAL 999
V V Q + ++V++ G + VV + G+ V+Y+ + ++P +
Sbjct: 4560 VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNT 4618
Query: 1000 CGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGC----------GATEPG- 1046
G CG +DD L G +N A + W + ++P C T PG
Sbjct: 4619 KGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGG 4678
Query: 1047 --DCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGP 1104
P D + C ++ D F +CH+ + PQ CV+D C +PG S
Sbjct: 4679 GKTTPHKDCTPSPL------CQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE 4730
Query: 1105 LCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1162
C +L YAA C + WR+ C + CP H Y+AC +C
Sbjct: 4731 -CASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN- 4787
Query: 1163 GSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEG 1219
+ EGC C EG +A + C + +CGCV G + P + C C EG
Sbjct: 4788 NTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEG 4843
Query: 1220 GL-VSCESSSCG--PHEACQPSGGSLGCVAVGSSTC 1252
G + C+ C P C G L + TC
Sbjct: 4844 GSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 4879
Score = 117 bits (294), Expect = 2e-25
Identities = 119/428 (27%), Positives = 183/428 (42%), Gaps = 56/428 (13%)
Query: 4459 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 4505
+P+ +G QPV + C WGDPHYVT DG + +QG C Y+L
Sbjct: 4453 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 4512
Query: 4506 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 4560
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 4513 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 4569
Query: 4561 ALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQ 4618
ALP++ L + SG + VV G+ ++++G SF +R+P + + G CG
Sbjct: 4570 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 4627
Query: 4619 DPADDLKAVGGK-PAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVISA 4673
+DD G+ + + Q SKP CP + ++ + GG
Sbjct: 4628 TTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDC 4687
Query: 4674 TDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGA 4724
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 4688 TPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNI 4746
Query: 4725 QLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG---F 4779
L +WR C ++CP+H Y+ CG + +C S S+ + + EGC C G +
Sbjct: 4747 CL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNY 4804
Query: 4780 VLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQ-EGAACGPH 4836
D CV CGC+ D GE F +C + C C GG + CQ + + P
Sbjct: 4805 APGFDVCVKT--CGCVGPDNVPREFGEHF--EFDC-KNCVCLEGGSGIICQPKRCSQKPV 4859
Query: 4837 EECRLEDG 4844
C +EDG
Sbjct: 4860 THC-VEDG 4866
>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 319 bits (818), Expect = 4e-86
Identities = 290/1160 (25%), Positives = 472/1160 (40%), Gaps = 170/1160 (14%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 510 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 565
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 566 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 624
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 625 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 679
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 737
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 738 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 795
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 855
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 856 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 915
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 972
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 973 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1031
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1032 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1089
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1090 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1149
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1150 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1207
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1208 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1231
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1232 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1275
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1276 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 1335
L ++ +V+ +N + + ++ + + V + + L +K +G
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFF 932
Query: 1336 MKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 1394
++ + + G +V+ + + + +D + + V + ++ GLCGN++
Sbjct: 933 LE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFD 987
Query: 1395 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 1454
+D N + NA FG+SW +SP PC +K P
Sbjct: 988 KCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCE------AHQNKFP------ 1035
Query: 1455 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSAC 1512
Y K+E C +L S +SC ++D K+C D C GG+ LC++I AY C
Sbjct: 1036 YAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKC 1092
Query: 1513 QAAGGHVEPWRTETFCPMEC 1532
G + WR+ T C ++C
Sbjct: 1093 CQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (808), Expect = 6e-85
Identities = 296/1191 (24%), Positives = 469/1191 (39%), Gaps = 156/1191 (13%)
Query: 2022 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 2075
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 2134
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 2135 QIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 2194
N + +++ +G+ +TLP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 2195 VRLRVPAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 2246
+ L++ + G CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 2247 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2304
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 2305 GLCPAVATYVAACQAAGAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
C A Y AC AG +++WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 2363 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGE 2422
C +GC C G V+ TC+ + C C Y +G C C C GG
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE--CTE-CVC-VGGV 412
Query: 2423 VSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 2482
+C C C GD H+TTFDGR + F+G C Y+L +
Sbjct: 413 WNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK- 452
Query: 2483 CGTRPGLHRFAV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLP 2540
GT G +F + LQ+ N G V + + + +F ++ + + +
Sbjct: 453 -GT--GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFN 509
Query: 2541 VVLANGQIRASQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQLMCGLCGNYNG 2596
+ NG + S ++++T FGL++ + + Y+++T + + GLCG +NG
Sbjct: 510 L---NGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNG 564
Query: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656
+ +DDF P+G G N+W S C P P I +
Sbjct: 565 NIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAAHCDV 621
Query: 2657 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 2716
+E + CH + P + C D C G S LC+ + Y C
Sbjct: 622 IHQEL----------FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQH 669
Query: 2717 GGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 2776
G ++ +FC + C + Y C+ C C +LS+P QC D CAEGC C G Y
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYE 729
Query: 2777 G--QACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQE-------HSCKP 2827
CVPI C C++ G+ Y+P + LI C C G V C E H C
Sbjct: 730 DTLNFCVPIFHCRCHYRGSVYQPGE--LIPTPSGLCQCSNG-TVKCDELATPSAVHICPE 786
Query: 2828 GQV---CQ------PSGGI------------LSCVNKDPC-HGVTCRPQETCKEQGGQGV 2865
G+ C+ P+GG+ +C PC G C P C+ +G
Sbjct: 787 GKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNC 844
Query: 2866 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR 2925
A C ++GD HY+SFDG ++D+ C L + + + +V +N+
Sbjct: 845 TYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKC 897
Query: 2926 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 2985
+ + + V ++ T I ++ D K + +G + + + + +V
Sbjct: 898 FDNDIVCSKSVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIV 949
Query: 2986 ADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 3042
F + + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 3043 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 3102
SW +C T Q + P + F +C + SF
Sbjct: 1010 DSW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSF 1061
Query: 3103 FKGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 3151
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (807), Expect = 8e-85
Identities = 297/1191 (24%), Positives = 470/1191 (39%), Gaps = 156/1191 (13%)
Query: 3223 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 3276
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 3277 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 3335
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 3336 QIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 3395
N + +++ +G+ +TLP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 3396 VRLRVPAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 3447
+ L++ + G CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 3448 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 3505
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 3506 GLCPAVATYVAACQAAGAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563
C A Y AC AG +++WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 3564 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGE 3623
C +GC C G V+ TC+ + C C Y +G C C C GG
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE--CTE-CVC-VGGV 412
Query: 3624 VSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQT 3683
+C C C GD H+TTFDG + F+G C Y+L +
Sbjct: 413 WNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK- 452
Query: 3684 CGTRPGLHRFAV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLP 3741
GT G +F + LQ+ N G V + + + +F ++ + + +
Sbjct: 453 -GT--GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFN 509
Query: 3742 VVLANGQIRASQHGS-DVVIETDFGLRVAYDLV---YYVRVTVPGNYYQLMCGLCGNYNG 3797
+ NG + S ++++T FGL++ + + Y+++T + + GLCG +NG
Sbjct: 510 L---NGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNG 564
Query: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857
+ +DDF P+G G N+W S C P P D C ++
Sbjct: 565 NIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV-------VDPCNIN-QQNI 613
Query: 3858 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 3917
C ++ + CH + P + C D C G S LC+ + Y C
Sbjct: 614 GYAAHCDVIHQEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQH 669
Query: 3918 GGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 3977
G ++ +FC + C + Y C+ C C +LS+P QC D CAEGC C G Y
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYE 729
Query: 3978 G--QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQE-------HSCKP 4028
CVPI C C++ G Y+P + LI C C G V C E H C
Sbjct: 730 DTLNFCVPIFHCRCHYRGSVYQPGE--LIPTPSGLCQCSNG-TVKCDELATPSAVHICPE 786
Query: 4029 GQV---CQ------PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGV 4066
G+ C+ P+GG+ +C PC G C P C+ +G
Sbjct: 787 GKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNC 844
Query: 4067 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR 4126
A C ++GD HY+SFDG ++D+ C L + + + +V +N+
Sbjct: 845 TYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKC 897
Query: 4127 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV 4186
+ + + V ++ T I ++ D K + +G + + + + +V
Sbjct: 898 FDNDIVCSKSVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIV 949
Query: 4187 ADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 4243
F + + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 4244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
SW +C T Q + P S F +C + SF
Sbjct: 1010 DSW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSF 1061
Query: 4304 FKGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 4352
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (806), Expect = 1e-84
Identities = 304/1177 (25%), Positives = 468/1177 (39%), Gaps = 182/1177 (15%)
Query: 1646 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 1696
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 1697 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 1754
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 1755 RVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 1814
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 1815 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 1874
CGN + ++D + I ++ SW D P + +E
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEA 257
Query: 1875 PGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAA 1933
F C L PF +CH ++ P + CV D+C D + C+A Y AC A
Sbjct: 258 IFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHA 313
Query: 1934 GVVIEDWRAQV-GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGP---CVEGCQC 1989
G I+DWR C C ++ + C S CP +C T C G C++GC C
Sbjct: 314 GYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQCLGSNLHCLDGCYC 367
Query: 1990 DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCG 2049
G V+ C+ L N C C +G + GS+ + C++ C C GG CT C
Sbjct: 368 PDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV--GGVWNCTEQDC- 420
Query: 2050 LGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGA 2109
PV +C GD H+ T DG ++F G C+Y+L G
Sbjct: 421 ----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQYILVKGT-----GK 456
Query: 2110 ENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQVDGVFVTLP---F 2162
+ FT+T+ + + +S+TL + +N +TL G +T P F
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR--------GGQILTSPNQGF 508
Query: 2163 QLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAGSLCGLCGNYNQDPA 2219
L+ ++ LS +++ TT GL + F DG+ + +++ +A+ GLCG +N +
Sbjct: 509 NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGLCGTFNGNIR 567
Query: 2220 DDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISA 2271
DD + G G W+V C V P PC QQ + G C VI
Sbjct: 568 DDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ-NIGYAAHCDVIHQ 624
Query: 2272 TDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD 2331
APCH + P Y+Q C DAC+ LC A+A Y C G + +
Sbjct: 625 E--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 2332 FCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG--DTCVPVGQ 2389
FC C Y C C SC SLS+PE C C EGC C G + CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFH 740
Query: 2390 CGCLHDDRYYPLGQTFYPGPG----------CDSLCR------CREG------------- 2420
C C + Y G+ G CD L C EG
Sbjct: 741 CRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPEL 800
Query: 2421 --GEVSCEPS--SCGPHETCRPSGGSL-GCVAVGST---------------TCQASGDPH 2460
G V+CE + + + TC PS + GCV C GD H
Sbjct: 801 PAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRH 860
Query: 2461 YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT 2520
Y +FDG +D++ C L ++ +V+ +N + + ++ + + V +
Sbjct: 861 YYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTE 916
Query: 2521 LRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTV 2579
+ L +K +G ++ + + G +V+ + + + +D + + V
Sbjct: 917 IYLNDTPYKQKQSGFFLE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKV 971
Query: 2580 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 2639
+ + GLCGN++ +D N + NA FG+SW +S P T P
Sbjct: 972 GPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCES---PDETIKP-- 1026
Query: 2640 EGCIPSEECPPELEK-KYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--G 2696
C K Y K+E C +L S +SC ++D K+C D C G
Sbjct: 1027 --------CEAHQNKFPYAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLG 1075
Query: 2697 GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMEC 2733
G+ LC++I AY C G + WR+ T C ++C
Sbjct: 1076 GDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 313 bits (803), Expect = 2e-84
Identities = 309/1191 (25%), Positives = 473/1191 (39%), Gaps = 186/1191 (15%)
Query: 2833 PSGGI-LSCVNKDPCHGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHY 2882
PSG C+N G C TC Q G + +PN + C WG H+
Sbjct: 18 PSGSCPYECLN-----GAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHF 72
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAA 2940
+FDG + F G C+Y+ A C + + +TV N + G+ Y + +
Sbjct: 73 ETFDGIYYYFPGNCSYIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFS 127
Query: 2941 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV 3000
I I+ EI K NG+ LP ++ G+I + + A L+ FG +++D +
Sbjct: 128 NQEEIRIYGHEIKK---NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGI 182
Query: 3001 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 3060
+ L + G CGLCGN + ++D + I ++ SW D
Sbjct: 183 YLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPS 242
Query: 3061 SCPTCPEDRLEQYEGPGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 3119
P + +E F C L PF +CH ++ P + CV D+C D +
Sbjct: 243 DFPNPCSSGMPAFEAIFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ET 298
Query: 3120 LCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPA 3178
C+A Y AC AG I+DWR C C ++ + C CP +C T
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEK 352
Query: 3179 VCEGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 3235
C G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVC 408
Query: 3236 GPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 3295
GG CT C PV +C GD H+ T DG + F G C
Sbjct: 409 V--GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMC 446
Query: 3296 EYLLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRK 3351
+Y+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 447 QYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR----- 496
Query: 3352 LQVDGVFVTLP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYA 3405
G +T P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 ---GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWK 552
Query: 3406 GSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQ 3457
GLCG +N + DD + G G W+V C V P PC Q
Sbjct: 553 RRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQ 610
Query: 3458 QESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAA 3517
Q + G C VI APCH + P Y+Q C DAC+ LC A+A Y
Sbjct: 611 Q-NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 3518 CQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG 3577
C G + + FC C Y C C SC SLS+PE C C EGC C G
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEG 725
Query: 3578 FVLSG--DTCVPVGQCGCLHDDRYYPLGQTFYPGPG----------CDSLCR------CR 3619
+ CVP+ C C + Y G+ G CD L C
Sbjct: 726 KFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICP 785
Query: 3620 EG---------------GEVSCEPS--SCGPHETCRPSGGSL-GCVAVGST--------- 3652
EG G V+CE + + + TC PS + GCV
Sbjct: 786 EGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCT 845
Query: 3653 ------TCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 3706
C GD HY +FDG +D++ C L ++ +V+ +N +
Sbjct: 846 YYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDND 901
Query: 3707 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFG 3765
+ ++ + + V + + L +K +G ++ + + G +V+ +
Sbjct: 902 IVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLE-----NKSTYQLWKAGYYIVVYFPEKD 956
Query: 3766 LRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVV 3825
+ + +D + + V + + GLCGN++ +D N + NA FG+SW
Sbjct: 957 ITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQ 1016
Query: 3826 PDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 3885
+S P T P A +K P Y K+E C +L S +SC ++D
Sbjct: 1017 CES---PDETIKPCEA---HQNKFP------YAKKE-CSILYSDI--FASCRNVIDVTSF 1061
Query: 3886 LKDCIFDLCLG--GGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMEC 3934
K+C D C GG+ LC++I AY C G + WR+ T C ++C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 307 bits (787), Expect = 2e-82
Identities = 308/1190 (25%), Positives = 459/1190 (38%), Gaps = 222/1190 (18%)
Query: 4048 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 4098
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 4099 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 4156
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 4157 RVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 4216
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 4217 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 4276
CGN + ++D + I ++ SW D C P D
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-------KCVLTPSD------- 243
Query: 4277 PGFCGPLSSGTGG--------------PFTTCHAHVPPESFFKGCVLDVCMGGGDRDILC 4322
F P SSG PF +CH ++ P + CV D+C D + C
Sbjct: 244 --FPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYC 300
Query: 4323 KALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVC 4381
+A Y AC AG I+DWR C C ++ + C CP +C T C
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQC 354
Query: 4382 EGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 4438
G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 355 LGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV- 409
Query: 4439 GGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY 4498
GG CT C PV +C GD H+ T DG + F G C+Y
Sbjct: 410 -GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQY 448
Query: 4499 LLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQ 4554
+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 449 ILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR------- 496
Query: 4555 VDGVFVALP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAAS 4608
G + P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 -GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRR 554
Query: 4609 LCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQE 4660
GLCG +N + DD + G G W+V C V P PC QQ
Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ- 611
Query: 4661 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 4720
+ G C VI APCH + P Y+Q C DAC+ LC A+A Y C
Sbjct: 612 NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCG 667
Query: 4721 AAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG-- 4778
G + + FC + C Y C C SC SLS+PE C C EGC C G
Sbjct: 668 QHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKF 727
Query: 4779 FVLSGDTCVPVGQCGCLHDGRYYPLGEVF------------------------------- 4807
+ + + CVP+ C C + G Y GE+
Sbjct: 728 YEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEG 787
Query: 4808 -------YPGPE-------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDGVQ 4846
+P PE CE C C P C G C P CR G+
Sbjct: 788 KEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RGMF 842
Query: 4847 ACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAG 4905
C C C G HY + DG YD C L + D D S++ +
Sbjct: 843 NCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKKCF 898
Query: 4906 DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------MVL 4954
D +V ++S+ + D P + E ++ +V
Sbjct: 899 DND--IVCSKSVLISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIVVY 951
Query: 4955 QTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAA 5014
K + +L+D + + + ++ +L GLCGNF+ S+D N + FG +
Sbjct: 952 FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011
Query: 5015 WRAPGSSKGCGEGCGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSEYF 5073
W A G + E P C A + PY E C L + FA+C+ V+ + +
Sbjct: 1012 W-ALGQCESPDETIKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTSFA 1062
Query: 5074 RQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
+ C D C GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 306 bits (783), Expect = 5e-82
Identities = 293/1182 (24%), Positives = 468/1182 (39%), Gaps = 143/1182 (12%)
Query: 820 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 877
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 878 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 935
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 995
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 996 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1053
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1054 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1113 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1171
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1172 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1231
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1232 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRF 1291
C GD H+TTFDGR + F+G C Y+L + GT G +F
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GT--GKDKF 459
Query: 1292 AV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRA 1349
+ LQ+ N G V + + + +F ++ + + + + NG +
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNL---NGIVEI 516
Query: 1350 SQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN 1405
S ++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+
Sbjct: 517 QTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPS 574
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLS 1465
G G N+W S C P P I ++ C ++
Sbjct: 575 GMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIH 623
Query: 1466 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE 1525
+ CH + P + C D C G S LC+ + Y C G ++ +RT+
Sbjct: 624 QEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQ 678
Query: 1526 -TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPI 1582
+FC + C Y C+ C C +LS+P QC D CAEGC C G Y CVPI
Sbjct: 679 ISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1583 QQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE-------HSCKPGQV---CQ- 1631
C C++ G Y+P + LI C C G + C E H C G+ C+
Sbjct: 739 FHCRCHYRGSVYQPGE--LIPTPSGLCQCSNGT-VKCDELATPSAVHICPEGKEYFDCRF 795
Query: 1632 -----PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGVCLPNYEATC 1673
P+GG+ +C PC G C P C+ +G A C
Sbjct: 796 PDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVC 853
Query: 1674 WLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVR 1733
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 854 TIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSK 906
Query: 1734 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQ 1790
V ++ T I ++ D K + +G + + + + +V F +
Sbjct: 907 SVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIVVYFPEKDIT 958
Query: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
+ +D + + + + + GLCGN D+ +ND N + ++G SW
Sbjct: 959 ILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW------ 1012
Query: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 1910
+C T Q + P + F +C + SF K C D C
Sbjct: 1013 --ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTC 1070
Query: 1911 MG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 1950
GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1071 NCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 254 bits (648), Expect = 2e-66
Identities = 226/841 (26%), Positives = 342/841 (40%), Gaps = 99/841 (11%)
Query: 4424 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 4477
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 4478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 4536
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 4537 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 4596
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 4648
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 4649 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 4706
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 4707 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 4764
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 4765 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 4824
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 4825 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 4883
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 4884 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 4933
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 4934 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 4990
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 4991 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 5050
GN DDF+ P+G + + AWR SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 5051 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 5110
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 5111 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 5168
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 5169 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 5227
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 5228 C 5228
C
Sbjct: 793 C 793
Score = 201 bits (512), Expect = 1e-50
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 455 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 572
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 573 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 632 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 686
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 687 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 745
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 746 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 803
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 804 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 824
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 825 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 875
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 876 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 935
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 994
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1054
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1055 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1105
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1106 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1148
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 85.9 bits (211), Expect = 1e-15
Identities = 98/406 (24%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 464 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 521
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 522 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 575
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 576 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 632
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 633 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 690 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 749
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 750 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 805
Y+ C C +C + S E CVC G V C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSE 1767
Query: 806 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 846
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 81.6 bits (200), Expect = 2e-14
Identities = 96/389 (24%), Positives = 145/389 (37%), Gaps = 47/389 (12%)
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2130
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2131 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2190
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 2191 G-----DSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 2233
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 2292
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 2293 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPG 2352
++ + C A++ YVA C + +WR PD+C CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 2353 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGCL-HDDRYYPLGQTFY 2406
G S RE CVC G VL C+P +C C +D+ G+ +
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIWN 1778
Query: 2407 PGPGCDSLCRCREGGEVSCEPSSCGPHET 2435
G +L +C E G + C T
Sbjct: 1779 GGIDECTLYKCLENGSIIPIEPDCDEEPT 1807
Score = 81.6 bits (200), Expect = 2e-14
Identities = 96/389 (24%), Positives = 145/389 (37%), Gaps = 47/389 (12%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 3331
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 3332 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 3391
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 3392 G-----DSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 3434
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 3493
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 3494 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPG 3553
++ + C A++ YVA C + +WR PD+C CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 3554 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGCL-HDDRYYPLGQTFY 3607
G S RE CVC G VL C+P +C C +D+ G+ +
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPRTAGEIWN 1778
Query: 3608 PGPGCDSLCRCREGGEVSCEPSSCGPHET 3636
G +L +C E G + C T
Sbjct: 1779 GGIDECTLYKCLENGSIIPIEPDCDEEPT 1807
Score = 79.0 bits (193), Expect = 1e-13
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 984 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1031
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1032 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1084
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1145 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1198
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1199 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1236
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Score = 78.6 bits (192), Expect = 2e-13
Identities = 100/440 (22%), Positives = 165/440 (37%), Gaps = 73/440 (16%)
Query: 4818 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 4877
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 4878 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 4927
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 4928 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 4983
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 4984 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRAPGS----SKGCGEGCGPQGCP 5034
GLCG N + DD + NG+ +++E G +W S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 5035 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 5094
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 5095 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 5152
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 5153 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 5206
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTVLHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 5207 TCQAAGC--PPGRVCEVKAE 5224
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 78.2 bits (191), Expect = 2e-13
Identities = 88/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 4532
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 4533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 4592
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 4593 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 4635
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 4636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 4694
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 4695 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 4754
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 4755 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 4794
G S RE CVC G VL C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 66.2 bits (160), Expect = 8e-10
Identities = 91/390 (23%), Positives = 141/390 (36%), Gaps = 56/390 (14%)
Query: 1659 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 1716
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 1717 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 1771
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 1772 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 1822
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 1823 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 1879
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 1880 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 1939
L F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1940 WRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 1996
WR C ++CPE Y+ C PC A C E C C G VL
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTVLHRPH 1751
Query: 1997 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 2026
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 66.2 bits (160), Expect = 8e-10
Identities = 91/390 (23%), Positives = 142/390 (36%), Gaps = 56/390 (14%)
Query: 4061 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 4118
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 4119 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 4173
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 4174 ISVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 4224
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 4225 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 4281
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 4282 PLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 4341
L + F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLLNRR--IFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 4342 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 4398
WR C ++CPE Y+ C PC A C E C C G VL
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTVLHRPH 1751
Query: 4399 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 65.9 bits (159), Expect = 1e-09
Identities = 91/390 (23%), Positives = 141/390 (36%), Gaps = 56/390 (14%)
Query: 2860 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 2917
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 2918 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 2972
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 2973 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 3023
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 3024 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 3080
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 3141 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 3197
WR C ++CPE Y+ C PC A C E C C G VL
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTVLHRPH 1751
Query: 3198 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 3227
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 58.9 bits (141), Expect = 1e-07
Identities = 112/530 (21%), Positives = 177/530 (33%), Gaps = 113/530 (21%)
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGF--ALSGESC 1183
WR E C C ++ CS L+C LP GC C + + DE + C
Sbjct: 1279 WRYEP-CATPC-----FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Query: 1184 LPLASCGCVHQGTYHPPGQTFYP-----------------------GPGC-----DSLCH 1215
+P+ + T PP + P G C D +
Sbjct: 1333 IPVIPT----EPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYD 1388
Query: 1216 CQEGGLVSCE------SSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDP 1258
C + ++ E S +C P + P G G C C+ S +
Sbjct: 1389 CSQYICLNMEWQLYNWSLNC-PKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSEL 1447
Query: 1259 HYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 1318
TFDG Y+L + G H G + + V
Sbjct: 1448 SIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIH 1507
Query: 1319 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLV 1371
+ + + KV V+ + + LP ++ ++ GS VI T GL + + D+
Sbjct: 1508 KIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIH 1565
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVV 1423
+ R + +Y + +CG+C N DP DD + NG+ N + G SWE EV
Sbjct: 1566 FGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVT 1621
Query: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
P T DC +C L ++ CH V P+
Sbjct: 1622 MRRPVRNCT-----EHDC---SQCIDLLNRRI---------------FIPCHDKVSPEDF 1658
Query: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
+ + + C + AYV+ C ++ WRT +C + CP Y+ C
Sbjct: 1659 CEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVR 1714
Query: 1544 TCSLGCSALSAPPQCQDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 1587
C + L+ C E C C G + + C+P ++C C
Sbjct: 1715 PCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 58.2 bits (139), Expect = 2e-07
Identities = 84/422 (19%), Positives = 145/422 (34%), Gaps = 58/422 (13%)
Query: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 2512
C + TFDG Y+L + G H G + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2513 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY--- 2569
V + + + KV V+ + + LP ++ ++ GS VI T GL + +
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 2570 ----DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWEE 2622
D+ + R + +Y + +CG+C N DP DD + NG+ N + G SWE
Sbjct: 1559 TGIIDIHFGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 2623 VVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQ 2682
+ P C +C L ++ CH V P+
Sbjct: 1615 EKSFEVTMRRPVRNCTEHDC---SQCIDLLNRRI---------------FIPCHDKVSPE 1656
Query: 2683 GPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELC 2742
+ + + C + AYV+ C ++ WR +C + CP+ Y+ C
Sbjct: 1657 DFCEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPC 1712
Query: 2743 ADTCSLGCSALSAPLQCPDGC---AEGCQCDSGFLY---NGQACVPIQQCGCYHNGAYYE 2796
C + L+ C E C C G + + C+P ++C C +
Sbjct: 1713 VRPCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 2797 PEQTVL---IDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGIL-------SCVNKD 2844
+ ID C G ++ E C +P VC+ ++ +C +K+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPI-EPDCDEEPTPVCEREAEVVMGIIDKWTCCSKE 1830
Query: 2845 PC 2846
C
Sbjct: 1831 VC 1832
Score = 57.0 bits (136), Expect = 5e-07
Identities = 72/352 (20%), Positives = 123/352 (34%), Gaps = 45/352 (12%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713
C + TFDG+ Y+L + G H G + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 3714 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY--- 3770
V + + + KV V+ + + LP ++ ++ GS VI T GL + +
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 3771 ----DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWEE 3823
D+ + R + +Y + +CG+C N DP DD + NG+ N + G SWE
Sbjct: 1559 TGIIDIHFGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 3824 VVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQ 3883
+ P C +C L ++ CH V P+
Sbjct: 1615 EKSFEVTMRRPVRNCTEHDC---SQCIDLLNRRI---------------FIPCHDKVSPE 1656
Query: 3884 GPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELC 3943
+ + + C + AYV+ C ++ WR +C + CP+ Y+ C
Sbjct: 1657 DFCEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPC 1712
Query: 3944 ADTCSLGCSALSAPLQCPDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 3989
C + L+ C E C C G + + C+P ++C C
Sbjct: 1713 VRPCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763
Score = 47.0 bits (110), Expect = 5e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 5193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 5252
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 5253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 5305
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 5306 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 5364
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 5365 AGKLCGACGNFDGDQTNDWHDSQE 5388
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
sapiens]
Length = 2250
Score = 319 bits (818), Expect = 4e-86
Identities = 290/1160 (25%), Positives = 472/1160 (40%), Gaps = 170/1160 (14%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 510 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 565
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 566 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 624
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 625 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 679
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 737
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 738 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 795
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 855
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 856 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 915
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 972
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 973 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1031
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1032 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1089
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1090 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1149
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1150 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1207
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1208 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1231
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1232 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1275
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1276 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 1335
L ++ +V+ +N + + ++ + + V + + L +K +G
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFF 932
Query: 1336 MKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 1394
++ + + G +V+ + + + +D + + V + ++ GLCGN++
Sbjct: 933 LE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFD 987
Query: 1395 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 1454
+D N + NA FG+SW +SP PC +K P
Sbjct: 988 KCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCE------AHQNKFP------ 1035
Query: 1455 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSAC 1512
Y K+E C +L S +SC ++D K+C D C GG+ LC++I AY C
Sbjct: 1036 YAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKC 1092
Query: 1513 QAAGGHVEPWRTETFCPMEC 1532
G + WR+ T C ++C
Sbjct: 1093 CQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (808), Expect = 6e-85
Identities = 296/1191 (24%), Positives = 469/1191 (39%), Gaps = 156/1191 (13%)
Query: 2022 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 2075
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 2134
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 2135 QIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 2194
N + +++ +G+ +TLP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 2195 VRLRVPAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 2246
+ L++ + G CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 2247 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2304
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 2305 GLCPAVATYVAACQAAGAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
C A Y AC AG +++WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 2363 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGE 2422
C +GC C G V+ TC+ + C C Y +G C C C GG
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE--CTE-CVC-VGGV 412
Query: 2423 VSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 2482
+C C C GD H+TTFDGR + F+G C Y+L +
Sbjct: 413 WNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK- 452
Query: 2483 CGTRPGLHRFAV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLP 2540
GT G +F + LQ+ N G V + + + +F ++ + + +
Sbjct: 453 -GT--GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFN 509
Query: 2541 VVLANGQIRASQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQLMCGLCGNYNG 2596
+ NG + S ++++T FGL++ + + Y+++T + + GLCG +NG
Sbjct: 510 L---NGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNG 564
Query: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656
+ +DDF P+G G N+W S C P P I +
Sbjct: 565 NIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAAHCDV 621
Query: 2657 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 2716
+E + CH + P + C D C G S LC+ + Y C
Sbjct: 622 IHQEL----------FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQH 669
Query: 2717 GGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 2776
G ++ +FC + C + Y C+ C C +LS+P QC D CAEGC C G Y
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYE 729
Query: 2777 G--QACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQE-------HSCKP 2827
CVPI C C++ G+ Y+P + LI C C G V C E H C
Sbjct: 730 DTLNFCVPIFHCRCHYRGSVYQPGE--LIPTPSGLCQCSNG-TVKCDELATPSAVHICPE 786
Query: 2828 GQV---CQ------PSGGI------------LSCVNKDPC-HGVTCRPQETCKEQGGQGV 2865
G+ C+ P+GG+ +C PC G C P C+ +G
Sbjct: 787 GKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNC 844
Query: 2866 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR 2925
A C ++GD HY+SFDG ++D+ C L + + + +V +N+
Sbjct: 845 TYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKC 897
Query: 2926 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 2985
+ + + V ++ T I ++ D K + +G + + + + +V
Sbjct: 898 FDNDIVCSKSVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIV 949
Query: 2986 ADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 3042
F + + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 3043 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 3102
SW +C T Q + P + F +C + SF
Sbjct: 1010 DSW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSF 1061
Query: 3103 FKGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 3151
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (807), Expect = 8e-85
Identities = 297/1191 (24%), Positives = 470/1191 (39%), Gaps = 156/1191 (13%)
Query: 3223 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 3276
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 3277 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 3335
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 3336 QIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 3395
N + +++ +G+ +TLP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 3396 VRLRVPAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 3447
+ L++ + G CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 3448 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 3505
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 3506 GLCPAVATYVAACQAAGAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563
C A Y AC AG +++WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 3564 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGE 3623
C +GC C G V+ TC+ + C C Y +G C C C GG
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE--CTE-CVC-VGGV 412
Query: 3624 VSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQT 3683
+C C C GD H+TTFDG + F+G C Y+L +
Sbjct: 413 WNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK- 452
Query: 3684 CGTRPGLHRFAV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLP 3741
GT G +F + LQ+ N G V + + + +F ++ + + +
Sbjct: 453 -GT--GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFN 509
Query: 3742 VVLANGQIRASQHGS-DVVIETDFGLRVAYDLV---YYVRVTVPGNYYQLMCGLCGNYNG 3797
+ NG + S ++++T FGL++ + + Y+++T + + GLCG +NG
Sbjct: 510 L---NGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNG 564
Query: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857
+ +DDF P+G G N+W S C P P D C ++
Sbjct: 565 NIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV-------VDPCNIN-QQNI 613
Query: 3858 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 3917
C ++ + CH + P + C D C G S LC+ + Y C
Sbjct: 614 GYAAHCDVIHQEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQH 669
Query: 3918 GGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 3977
G ++ +FC + C + Y C+ C C +LS+P QC D CAEGC C G Y
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYE 729
Query: 3978 G--QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQE-------HSCKP 4028
CVPI C C++ G Y+P + LI C C G V C E H C
Sbjct: 730 DTLNFCVPIFHCRCHYRGSVYQPGE--LIPTPSGLCQCSNG-TVKCDELATPSAVHICPE 786
Query: 4029 GQV---CQ------PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGV 4066
G+ C+ P+GG+ +C PC G C P C+ +G
Sbjct: 787 GKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNC 844
Query: 4067 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR 4126
A C ++GD HY+SFDG ++D+ C L + + + +V +N+
Sbjct: 845 TYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKC 897
Query: 4127 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV 4186
+ + + V ++ T I ++ D K + +G + + + + +V
Sbjct: 898 FDNDIVCSKSVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIV 949
Query: 4187 ADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 4243
F + + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 4244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
SW +C T Q + P S F +C + SF
Sbjct: 1010 DSW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSF 1061
Query: 4304 FKGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 4352
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (806), Expect = 1e-84
Identities = 304/1177 (25%), Positives = 468/1177 (39%), Gaps = 182/1177 (15%)
Query: 1646 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 1696
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 1697 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 1754
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 1755 RVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 1814
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 1815 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 1874
CGN + ++D + I ++ SW D P + +E
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEA 257
Query: 1875 PGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAA 1933
F C L PF +CH ++ P + CV D+C D + C+A Y AC A
Sbjct: 258 IFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHA 313
Query: 1934 GVVIEDWRAQV-GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGP---CVEGCQC 1989
G I+DWR C C ++ + C S CP +C T C G C++GC C
Sbjct: 314 GYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQCLGSNLHCLDGCYC 367
Query: 1990 DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCG 2049
G V+ C+ L N C C +G + GS+ + C++ C C GG CT C
Sbjct: 368 PDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV--GGVWNCTEQDC- 420
Query: 2050 LGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGA 2109
PV +C GD H+ T DG ++F G C+Y+L G
Sbjct: 421 ----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQYILVKGT-----GK 456
Query: 2110 ENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQVDGVFVTLP---F 2162
+ FT+T+ + + +S+TL + +N +TL G +T P F
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR--------GGQILTSPNQGF 508
Query: 2163 QLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAGSLCGLCGNYNQDPA 2219
L+ ++ LS +++ TT GL + F DG+ + +++ +A+ GLCG +N +
Sbjct: 509 NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGLCGTFNGNIR 567
Query: 2220 DDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISA 2271
DD + G G W+V C V P PC QQ + G C VI
Sbjct: 568 DDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ-NIGYAAHCDVIHQ 624
Query: 2272 TDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD 2331
APCH + P Y+Q C DAC+ LC A+A Y C G + +
Sbjct: 625 E--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 2332 FCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG--DTCVPVGQ 2389
FC C Y C C SC SLS+PE C C EGC C G + CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFH 740
Query: 2390 CGCLHDDRYYPLGQTFYPGPG----------CDSLCR------CREG------------- 2420
C C + Y G+ G CD L C EG
Sbjct: 741 CRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPEL 800
Query: 2421 --GEVSCEPS--SCGPHETCRPSGGSL-GCVAVGST---------------TCQASGDPH 2460
G V+CE + + + TC PS + GCV C GD H
Sbjct: 801 PAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRH 860
Query: 2461 YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT 2520
Y +FDG +D++ C L ++ +V+ +N + + ++ + + V +
Sbjct: 861 YYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTE 916
Query: 2521 LRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTV 2579
+ L +K +G ++ + + G +V+ + + + +D + + V
Sbjct: 917 IYLNDTPYKQKQSGFFLE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKV 971
Query: 2580 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 2639
+ + GLCGN++ +D N + NA FG+SW +S P T P
Sbjct: 972 GPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCES---PDETIKP-- 1026
Query: 2640 EGCIPSEECPPELEK-KYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--G 2696
C K Y K+E C +L S +SC ++D K+C D C G
Sbjct: 1027 --------CEAHQNKFPYAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLG 1075
Query: 2697 GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMEC 2733
G+ LC++I AY C G + WR+ T C ++C
Sbjct: 1076 GDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 313 bits (803), Expect = 2e-84
Identities = 309/1191 (25%), Positives = 473/1191 (39%), Gaps = 186/1191 (15%)
Query: 2833 PSGGI-LSCVNKDPCHGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHY 2882
PSG C+N G C TC Q G + +PN + C WG H+
Sbjct: 18 PSGSCPYECLN-----GAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHF 72
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAA 2940
+FDG + F G C+Y+ A C + + +TV N + G+ Y + +
Sbjct: 73 ETFDGIYYYFPGNCSYIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFS 127
Query: 2941 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV 3000
I I+ EI K NG+ LP ++ G+I + + A L+ FG +++D +
Sbjct: 128 NQEEIRIYGHEIKK---NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGI 182
Query: 3001 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 3060
+ L + G CGLCGN + ++D + I ++ SW D
Sbjct: 183 YLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPS 242
Query: 3061 SCPTCPEDRLEQYEGPGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 3119
P + +E F C L PF +CH ++ P + CV D+C D +
Sbjct: 243 DFPNPCSSGMPAFEAIFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ET 298
Query: 3120 LCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPA 3178
C+A Y AC AG I+DWR C C ++ + C CP +C T
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEK 352
Query: 3179 VCEGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 3235
C G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVC 408
Query: 3236 GPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 3295
GG CT C PV +C GD H+ T DG + F G C
Sbjct: 409 V--GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMC 446
Query: 3296 EYLLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRK 3351
+Y+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 447 QYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR----- 496
Query: 3352 LQVDGVFVTLP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYA 3405
G +T P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 ---GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWK 552
Query: 3406 GSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQ 3457
GLCG +N + DD + G G W+V C V P PC Q
Sbjct: 553 RRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQ 610
Query: 3458 QESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAA 3517
Q + G C VI APCH + P Y+Q C DAC+ LC A+A Y
Sbjct: 611 Q-NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 3518 CQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG 3577
C G + + FC C Y C C SC SLS+PE C C EGC C G
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEG 725
Query: 3578 FVLSG--DTCVPVGQCGCLHDDRYYPLGQTFYPGPG----------CDSLCR------CR 3619
+ CVP+ C C + Y G+ G CD L C
Sbjct: 726 KFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICP 785
Query: 3620 EG---------------GEVSCEPS--SCGPHETCRPSGGSL-GCVAVGST--------- 3652
EG G V+CE + + + TC PS + GCV
Sbjct: 786 EGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCT 845
Query: 3653 ------TCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 3706
C GD HY +FDG +D++ C L ++ +V+ +N +
Sbjct: 846 YYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDND 901
Query: 3707 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFG 3765
+ ++ + + V + + L +K +G ++ + + G +V+ +
Sbjct: 902 IVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLE-----NKSTYQLWKAGYYIVVYFPEKD 956
Query: 3766 LRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVV 3825
+ + +D + + V + + GLCGN++ +D N + NA FG+SW
Sbjct: 957 ITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQ 1016
Query: 3826 PDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 3885
+S P T P A +K P Y K+E C +L S +SC ++D
Sbjct: 1017 CES---PDETIKPCEA---HQNKFP------YAKKE-CSILYSDI--FASCRNVIDVTSF 1061
Query: 3886 LKDCIFDLCLG--GGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMEC 3934
K+C D C GG+ LC++I AY C G + WR+ T C ++C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 307 bits (787), Expect = 2e-82
Identities = 308/1190 (25%), Positives = 459/1190 (38%), Gaps = 222/1190 (18%)
Query: 4048 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 4098
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 4099 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 4156
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 4157 RVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 4216
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 4217 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 4276
CGN + ++D + I ++ SW D C P D
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-------KCVLTPSD------- 243
Query: 4277 PGFCGPLSSGTGG--------------PFTTCHAHVPPESFFKGCVLDVCMGGGDRDILC 4322
F P SSG PF +CH ++ P + CV D+C D + C
Sbjct: 244 --FPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYC 300
Query: 4323 KALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVC 4381
+A Y AC AG I+DWR C C ++ + C CP +C T C
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQC 354
Query: 4382 EGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 4438
G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 355 LGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV- 409
Query: 4439 GGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY 4498
GG CT C PV +C GD H+ T DG + F G C+Y
Sbjct: 410 -GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQY 448
Query: 4499 LLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQ 4554
+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 449 ILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR------- 496
Query: 4555 VDGVFVALP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAAS 4608
G + P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 -GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRR 554
Query: 4609 LCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQE 4660
GLCG +N + DD + G G W+V C V P PC QQ
Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ- 611
Query: 4661 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 4720
+ G C VI APCH + P Y+Q C DAC+ LC A+A Y C
Sbjct: 612 NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCG 667
Query: 4721 AAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG-- 4778
G + + FC + C Y C C SC SLS+PE C C EGC C G
Sbjct: 668 QHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKF 727
Query: 4779 FVLSGDTCVPVGQCGCLHDGRYYPLGEVF------------------------------- 4807
+ + + CVP+ C C + G Y GE+
Sbjct: 728 YEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEG 787
Query: 4808 -------YPGPE-------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDGVQ 4846
+P PE CE C C P C G C P CR G+
Sbjct: 788 KEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RGMF 842
Query: 4847 ACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAG 4905
C C C G HY + DG YD C L + D D S++ +
Sbjct: 843 NCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKKCF 898
Query: 4906 DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------MVL 4954
D +V ++S+ + D P + E ++ +V
Sbjct: 899 DND--IVCSKSVLISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIVVY 951
Query: 4955 QTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAA 5014
K + +L+D + + + ++ +L GLCGNF+ S+D N + FG +
Sbjct: 952 FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011
Query: 5015 WRAPGSSKGCGEGCGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSEYF 5073
W A G + E P C A + PY E C L + FA+C+ V+ + +
Sbjct: 1012 W-ALGQCESPDETIKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTSFA 1062
Query: 5074 RQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
+ C D C GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 306 bits (783), Expect = 5e-82
Identities = 293/1182 (24%), Positives = 468/1182 (39%), Gaps = 143/1182 (12%)
Query: 820 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 877
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 878 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 935
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 995
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 996 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1053
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1054 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1113 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1171
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1172 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1231
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1232 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRF 1291
C GD H+TTFDGR + F+G C Y+L + GT G +F
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GT--GKDKF 459
Query: 1292 AV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRA 1349
+ LQ+ N G V + + + +F ++ + + + + NG +
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNL---NGIVEI 516
Query: 1350 SQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN 1405
S ++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+
Sbjct: 517 QTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPS 574
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLS 1465
G G N+W S C P P I ++ C ++
Sbjct: 575 GMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIH 623
Query: 1466 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE 1525
+ CH + P + C D C G S LC+ + Y C G ++ +RT+
Sbjct: 624 QEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQ 678
Query: 1526 -TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPI 1582
+FC + C Y C+ C C +LS+P QC D CAEGC C G Y CVPI
Sbjct: 679 ISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1583 QQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE-------HSCKPGQV---CQ- 1631
C C++ G Y+P + LI C C G + C E H C G+ C+
Sbjct: 739 FHCRCHYRGSVYQPGE--LIPTPSGLCQCSNGT-VKCDELATPSAVHICPEGKEYFDCRF 795
Query: 1632 -----PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGVCLPNYEATC 1673
P+GG+ +C PC G C P C+ +G A C
Sbjct: 796 PDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVC 853
Query: 1674 WLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVR 1733
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 854 TIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSK 906
Query: 1734 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQ 1790
V ++ T I ++ D K + +G + + + + +V F +
Sbjct: 907 SVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIVVYFPEKDIT 958
Query: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
+ +D + + + + + GLCGN D+ +ND N + ++G SW
Sbjct: 959 ILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW------ 1012
Query: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 1910
+C T Q + P + F +C + SF K C D C
Sbjct: 1013 --ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTC 1070
Query: 1911 MG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 1950
GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1071 NCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 254 bits (648), Expect = 2e-66
Identities = 226/841 (26%), Positives = 342/841 (40%), Gaps = 99/841 (11%)
Query: 4424 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 4477
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 4478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 4536
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 4537 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 4596
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 4648
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 4649 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 4706
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 4707 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 4764
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 4765 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 4824
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 4825 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 4883
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 4884 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 4933
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 4934 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 4990
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 4991 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 5050
GN DDF+ P+G + + AWR SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 5051 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 5110
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 5111 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 5168
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 5169 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 5227
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 5228 C 5228
C
Sbjct: 793 C 793
Score = 201 bits (512), Expect = 1e-50
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 455 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 572
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 573 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 632 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 686
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 687 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 745
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 746 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 803
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 804 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 824
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 825 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 875
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 876 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 935
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 994
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1054
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1055 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1105
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1106 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1148
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 85.5 bits (210), Expect = 1e-15
Identities = 97/406 (23%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 464 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 521
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 522 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 575
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 576 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 632
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 633 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 690 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 749
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 750 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 805
Y+ C C +C + S E CVC G + C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSE 1767
Query: 806 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 846
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 81.3 bits (199), Expect = 2e-14
Identities = 95/389 (24%), Positives = 145/389 (37%), Gaps = 47/389 (12%)
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2130
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2131 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2190
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 2191 G-----DSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 2233
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 2292
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 2293 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPG 2352
++ + C A++ YVA C + +WR PD+C CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 2353 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGCL-HDDRYYPLGQTFY 2406
G S RE CVC G +L C+P +C C +D+ G+ +
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWN 1778
Query: 2407 PGPGCDSLCRCREGGEVSCEPSSCGPHET 2435
G +L +C E G + C T
Sbjct: 1779 GGIDECTLYKCLENGSIIPIEPDCDEEPT 1807
Score = 81.3 bits (199), Expect = 2e-14
Identities = 95/389 (24%), Positives = 145/389 (37%), Gaps = 47/389 (12%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 3331
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 3332 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 3391
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 3392 G-----DSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 3434
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 3493
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 3494 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPG 3553
++ + C A++ YVA C + +WR PD+C CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 3554 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGCL-HDDRYYPLGQTFY 3607
G S RE CVC G +L C+P +C C +D+ G+ +
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWN 1778
Query: 3608 PGPGCDSLCRCREGGEVSCEPSSCGPHET 3636
G +L +C E G + C T
Sbjct: 1779 GGIDECTLYKCLENGSIIPIEPDCDEEPT 1807
Score = 79.0 bits (193), Expect = 1e-13
Identities = 100/440 (22%), Positives = 165/440 (37%), Gaps = 73/440 (16%)
Query: 4818 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 4877
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 4878 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 4927
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 4928 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 4983
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 4984 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRAPGS----SKGCGEGCGPQGCP 5034
GLCG N + DD + NG+ +++E G +W S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 5035 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 5094
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 5095 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 5152
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 5153 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 5206
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTILHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 5207 TCQAAGC--PPGRVCEVKAE 5224
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 78.6 bits (192), Expect = 2e-13
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 984 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1031
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1032 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1084
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1145 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1198
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1199 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1236
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Score = 77.8 bits (190), Expect = 3e-13
Identities = 87/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 4532
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 4533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 4592
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 4593 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 4635
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 4636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 4694
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 4695 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 4754
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 4755 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 4794
G S RE CVC G +L C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 65.9 bits (159), Expect = 1e-09
Identities = 90/390 (23%), Positives = 141/390 (36%), Gaps = 56/390 (14%)
Query: 1659 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 1716
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 1717 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 1771
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 1772 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 1822
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 1823 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 1879
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 1880 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 1939
L F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1940 WRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 1996
WR C ++CPE Y+ C PC A C E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPH 1751
Query: 1997 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 2026
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 65.9 bits (159), Expect = 1e-09
Identities = 90/390 (23%), Positives = 142/390 (36%), Gaps = 56/390 (14%)
Query: 4061 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 4118
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 4119 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 4173
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 4174 ISVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 4224
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 4225 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 4281
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 4282 PLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 4341
L + F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLLNRR--IFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 4342 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 4398
WR C ++CPE Y+ C PC A C E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPH 1751
Query: 4399 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 65.5 bits (158), Expect = 1e-09
Identities = 90/390 (23%), Positives = 141/390 (36%), Gaps = 56/390 (14%)
Query: 2860 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 2917
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 2918 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 2972
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 2973 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 3023
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 3024 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 3080
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 3141 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 3197
WR C ++CPE Y+ C PC A C E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPH 1751
Query: 3198 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 3227
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 59.3 bits (142), Expect = 1e-07
Identities = 112/530 (21%), Positives = 177/530 (33%), Gaps = 113/530 (21%)
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGF--ALSGESC 1183
WR E C C ++ CS L+C LP GC C + + DE + C
Sbjct: 1279 WRYEP-CATPC-----FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Query: 1184 LPLASCGCVHQGTYHPPGQTFYP-----------------------GPGC-----DSLCH 1215
+P+ + T PP + P G C D +
Sbjct: 1333 IPVIPT----EPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYD 1388
Query: 1216 CQEGGLVSCE------SSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDP 1258
C + ++ E S +C P + P G G C C+ S +
Sbjct: 1389 CSQYICLNMEWQLYNWSLNC-PKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSEL 1447
Query: 1259 HYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 1318
TFDG Y+L + G H G + + V
Sbjct: 1448 SIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIH 1507
Query: 1319 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLV 1371
+ + + KV V+ + + LP ++ ++ GS VI T GL + + D+
Sbjct: 1508 KIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIH 1565
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVV 1423
+ R + +Y + +CG+C N DP DD + NG+ N + G SWE EV
Sbjct: 1566 FGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVT 1621
Query: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
P T DC +C L ++ CH V P+
Sbjct: 1622 MRRPVRNCT-----EHDC---SQCIDLLNRRI---------------FIPCHDKVSPEDF 1658
Query: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
+ + + C + AYV+ C ++ WRT +C + CP Y+ C
Sbjct: 1659 CEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVR 1714
Query: 1544 TCSLGCSALSAPPQCQDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 1587
C + L+ C E C C G + + C+P ++C C
Sbjct: 1715 PCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 58.5 bits (140), Expect = 2e-07
Identities = 84/422 (19%), Positives = 145/422 (34%), Gaps = 58/422 (13%)
Query: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 2512
C + TFDG Y+L + G H G + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2513 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY--- 2569
V + + + KV V+ + + LP ++ ++ GS VI T GL + +
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 2570 ----DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWEE 2622
D+ + R + +Y + +CG+C N DP DD + NG+ N + G SWE
Sbjct: 1559 TGIIDIHFGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 2623 VVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQ 2682
+ P C +C L ++ CH V P+
Sbjct: 1615 EKSFEVTMRRPVRNCTEHDC---SQCIDLLNRRI---------------FIPCHDKVSPE 1656
Query: 2683 GPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELC 2742
+ + + C + AYV+ C ++ WR +C + CP+ Y+ C
Sbjct: 1657 DFCEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPC 1712
Query: 2743 ADTCSLGCSALSAPLQCPDGC---AEGCQCDSGFLY---NGQACVPIQQCGCYHNGAYYE 2796
C + L+ C E C C G + + C+P ++C C +
Sbjct: 1713 VRPCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 2797 PEQTVL---IDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGIL-------SCVNKD 2844
+ ID C G ++ E C +P VC+ ++ +C +K+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPI-EPDCDEEPTPVCEREAEVVMGIIDKWTCCSKE 1830
Query: 2845 PC 2846
C
Sbjct: 1831 VC 1832
Score = 57.4 bits (137), Expect = 4e-07
Identities = 72/352 (20%), Positives = 123/352 (34%), Gaps = 45/352 (12%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713
C + TFDG+ Y+L + G H G + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 3714 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY--- 3770
V + + + KV V+ + + LP ++ ++ GS VI T GL + +
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 3771 ----DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWEE 3823
D+ + R + +Y + +CG+C N DP DD + NG+ N + G SWE
Sbjct: 1559 TGIIDIHFGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 3824 VVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQ 3883
+ P C +C L ++ CH V P+
Sbjct: 1615 EKSFEVTMRRPVRNCTEHDC---SQCIDLLNRRI---------------FIPCHDKVSPE 1656
Query: 3884 GPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELC 3943
+ + + C + AYV+ C ++ WR +C + CP+ Y+ C
Sbjct: 1657 DFCEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPC 1712
Query: 3944 ADTCSLGCSALSAPLQCPDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 3989
C + L+ C E C C G + + C+P ++C C
Sbjct: 1713 VRPCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 47.0 bits (110), Expect = 5e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 5193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 5252
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 5253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 5305
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 5306 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 5364
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 5365 AGKLCGACGNFDGDQTNDWHDSQE 5388
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
Length = 2250
Score = 319 bits (818), Expect = 4e-86
Identities = 290/1160 (25%), Positives = 472/1160 (40%), Gaps = 170/1160 (14%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ++ +C+ G H+ TFDG Y G CSY + C D P
Sbjct: 45 ALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCG--DLEP 99
Query: 510 AFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSL---TRGEVGFVLVDNQRSRLPVSLSE- 565
++V N + L +V + S+SL + E+ + +++ + ++L +
Sbjct: 100 RYTVWVHNSPKC--------LGSVYSCYRSISLFFSNQEEIRIYGHEIKKNGISLTLPQT 151
Query: 566 -GRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLT 624
G++ + + +V+ FG + +D + L L + + CGLCGNYN +DDF+
Sbjct: 152 IGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFII 211
Query: 625 PDGALAPDAVEFASSWKLDDGD----YLCEDGCQNNCPACTPG-QAQHYEGDRLCGMLTK 679
D FA+SW + D L N C + P +A ++ C +L
Sbjct: 212 LQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEAIFFK----CQIL-- 265
Query: 680 LDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS-- 737
L PF CH+ +DP ++ CV DLC + + CR + YA+AC G + DWR
Sbjct: 266 LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEYARACSHAGYPIQDWRDDF 324
Query: 738 PANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGR--PCVEGCVCLPGFVASGGACVP 795
PA C C + + C CP +C C G C++GC C G V G C+
Sbjct: 325 PA-CTDKCDDSFVHRDCISCCPPTC---TFEKQCLGSNLHCLDGCYCPDGLVMDNGTCIS 380
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLG 855
+C C F GL + G ++ ++ C C C G T +Q CP +CSV
Sbjct: 381 LENCPCGFHGLAYSVGSKI--EQEC-TECVCVGGVWNCT---EQDCPV--QCSV------ 426
Query: 856 CYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQ 915
GD H+ +FDGR + F+G C Y+LV G++ + ++ G
Sbjct: 427 -----------VGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQNLGLV 475
Query: 916 TVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQA--ADGQVQV-FRQGRDAVVR 972
+ + + +V + R GQ+L P Q +G V++ +++
Sbjct: 476 CLQSITLILEDDFNKQVTLGR--GGQILTS------PNQGFNLNGIVEIQTLSSLFILLK 527
Query: 973 TDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNS 1031
T FGL + + + R+ ++ S++ GLCG FNG+ DD G N+
Sbjct: 528 TTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANA 587
Query: 1032 WQEETRPGCGATEPGDCPKLD--SLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVR 1089
W+ + C A P P +D ++ Q + C ++ F CH + P +
Sbjct: 588 WRVSST--CFA--PVHVPVVDPCNINQQNIGYAAHCDVIHQEL--FAPCHIYISPGLYYQ 641
Query: 1090 DCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGC 1149
C +D C S LC+ALA YA C G + C + C Y CS C
Sbjct: 642 LCRHDACKC--GSSCLCNALAHYAYLCGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFC 699
Query: 1150 PLSCGDLPVPGGCGSECHEGCVCDEG--FALSGESCLPLASCGCVHQGTYHPPGQTFYPG 1207
SC L P C +C EGC C EG + + C+P+ C C ++G+ + PG+
Sbjct: 700 LHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQPGELI--- 756
Query: 1208 PGCDSLCHCQEG----------------------------------GLVSCES--SSCGP 1231
P LC C G G V+CE+ ++
Sbjct: 757 PTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETTCANLAM 816
Query: 1232 HEACQPSGGSL-GCVAVGS---------------STCQASGDPHYTTFDGRRFDFMGTCV 1275
+ C PS + GCV + C GD HY +FDG +D++ C
Sbjct: 817 NFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQ 876
Query: 1276 YVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVD 1335
L ++ +V+ +N + + ++ + + V + + L +K +G
Sbjct: 877 VFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFF 932
Query: 1336 MKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYN 1394
++ + + G +V+ + + + +D + + V + ++ GLCGN++
Sbjct: 933 LE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFD 987
Query: 1395 GDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKK 1454
+D N + NA FG+SW +SP PC +K P
Sbjct: 988 KCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDETIKPCE------AHQNKFP------ 1035
Query: 1455 YQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--GGNLSILCSNIHAYVSAC 1512
Y K+E C +L S +SC ++D K+C D C GG+ LC++I AY C
Sbjct: 1036 YAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLGGDCECLCTSIAAYAYKC 1092
Query: 1513 QAAGGHVEPWRTETFCPMEC 1532
G + WR+ T C ++C
Sbjct: 1093 CQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (808), Expect = 6e-85
Identities = 296/1191 (24%), Positives = 469/1191 (39%), Gaps = 156/1191 (13%)
Query: 2022 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 2075
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 2134
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 2135 QIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 2194
N + +++ +G+ +TLP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 2195 VRLRVPAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 2246
+ L++ + G CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 2247 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 2304
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 2305 GLCPAVATYVAACQAAGAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
C A Y AC AG +++WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 2363 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGE 2422
C +GC C G V+ TC+ + C C Y +G C C C GG
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE--CTE-CVC-VGGV 412
Query: 2423 VSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQT 2482
+C C C GD H+TTFDGR + F+G C Y+L +
Sbjct: 413 WNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK- 452
Query: 2483 CGTRPGLHRFAV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLP 2540
GT G +F + LQ+ N G V + + + +F ++ + + +
Sbjct: 453 -GT--GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFN 509
Query: 2541 VVLANGQIRASQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQLMCGLCGNYNG 2596
+ NG + S ++++T FGL++ + + Y+++T + + GLCG +NG
Sbjct: 510 L---NGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNG 564
Query: 2597 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKY 2656
+ +DDF P+G G N+W S C P P I +
Sbjct: 565 NIRDDFLSPSGMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNINQQNIGYAAHCDV 621
Query: 2657 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 2716
+E + CH + P + C D C G S LC+ + Y C
Sbjct: 622 IHQEL----------FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQH 669
Query: 2717 GGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 2776
G ++ +FC + C + Y C+ C C +LS+P QC D CAEGC C G Y
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYE 729
Query: 2777 G--QACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQE-------HSCKP 2827
CVPI C C++ G+ Y+P + LI C C G V C E H C
Sbjct: 730 DTLNFCVPIFHCRCHYRGSVYQPGE--LIPTPSGLCQCSNG-TVKCDELATPSAVHICPE 786
Query: 2828 GQV---CQ------PSGGI------------LSCVNKDPC-HGVTCRPQETCKEQGGQGV 2865
G+ C+ P+GG+ +C PC G C P C+ +G
Sbjct: 787 GKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNC 844
Query: 2866 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR 2925
A C ++GD HY+SFDG ++D+ C L + + + +V +N+
Sbjct: 845 TYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKC 897
Query: 2926 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV 2985
+ + + V ++ T I ++ D K + +G + + + + +V
Sbjct: 898 FDNDIVCSKSVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIV 949
Query: 2986 ADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 3042
F + + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 3043 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESF 3102
SW +C T Q + P + F +C + SF
Sbjct: 1010 DSW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSF 1061
Query: 3103 FKGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 3151
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (807), Expect = 8e-85
Identities = 297/1191 (24%), Positives = 470/1191 (39%), Gaps = 156/1191 (13%)
Query: 3223 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 3276
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 3277 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 3335
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 3336 QIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 3395
N + +++ +G+ +TLP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 3396 VRLRVPAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 3447
+ L++ + G CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 3448 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 3505
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 3506 GLCPAVATYVAACQAAGAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEG 3563
C A Y AC AG +++WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 3564 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGE 3623
C +GC C G V+ TC+ + C C Y +G C C C GG
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGSKIEQE--CTE-CVC-VGGV 412
Query: 3624 VSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQT 3683
+C C C GD H+TTFDG + F+G C Y+L +
Sbjct: 413 WNCTEQDC-------------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK- 452
Query: 3684 CGTRPGLHRFAV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLP 3741
GT G +F + LQ+ N G V + + + +F ++ + + +
Sbjct: 453 -GT--GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFN 509
Query: 3742 VVLANGQIRASQHGS-DVVIETDFGLRVAYDLV---YYVRVTVPGNYYQLMCGLCGNYNG 3797
+ NG + S ++++T FGL++ + + Y+++T + + GLCG +NG
Sbjct: 510 L---NGIVEIQTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNG 564
Query: 3798 DPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKY 3857
+ +DDF P+G G N+W S C P P D C ++
Sbjct: 565 NIRDDFLSPSGMIEGTPQLHANAWRV---SSTCFAPVHVPV-------VDPCNIN-QQNI 613
Query: 3858 QKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAA 3917
C ++ + CH + P + C D C G S LC+ + Y C
Sbjct: 614 GYAAHCDVIHQEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQH 669
Query: 3918 GGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYN 3977
G ++ +FC + C + Y C+ C C +LS+P QC D CAEGC C G Y
Sbjct: 670 GVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYE 729
Query: 3978 G--QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQE-------HSCKP 4028
CVPI C C++ G Y+P + LI C C G V C E H C
Sbjct: 730 DTLNFCVPIFHCRCHYRGSVYQPGE--LIPTPSGLCQCSNG-TVKCDELATPSAVHICPE 786
Query: 4029 GQV---CQ------PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGV 4066
G+ C+ P+GG+ +C PC G C P C+ +G
Sbjct: 787 GKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNC 844
Query: 4067 CLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR 4126
A C ++GD HY+SFDG ++D+ C L + + + +V +N+
Sbjct: 845 TYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKC 897
Query: 4127 GNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLV 4186
+ + + V ++ T I ++ D K + +G + + + + +V
Sbjct: 898 FDNDIVCSKSVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIV 949
Query: 4187 ADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWG 4243
F + + +D + + + + + GLCGN D+ +ND N + ++G
Sbjct: 950 VYFPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFG 1009
Query: 4244 GSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESF 4303
SW +C T Q + P S F +C + SF
Sbjct: 1010 DSW--------ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSF 1061
Query: 4304 FKGCVLDVCMG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 4352
K C D C GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 315 bits (806), Expect = 1e-84
Identities = 304/1177 (25%), Positives = 468/1177 (39%), Gaps = 182/1177 (15%)
Query: 1646 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 1696
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 1697 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 1754
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 1755 RVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 1814
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 1815 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 1874
CGN + ++D + I ++ SW D P + +E
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPSDFPNPCSSGMPAFEA 257
Query: 1875 PGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAA 1933
F C L PF +CH ++ P + CV D+C D + C+A Y AC A
Sbjct: 258 IFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYCRAATEYARACSHA 313
Query: 1934 GVVIEDWRAQV-GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGP---CVEGCQC 1989
G I+DWR C C ++ + C S CP +C T C G C++GC C
Sbjct: 314 GYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQCLGSNLHCLDGCYC 367
Query: 1990 DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCG 2049
G V+ C+ L N C C +G + GS+ + C++ C C GG CT C
Sbjct: 368 PDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV--GGVWNCTEQDC- 420
Query: 2050 LGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGA 2109
PV +C GD H+ T DG ++F G C+Y+L G
Sbjct: 421 ----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQYILVKGT-----GK 456
Query: 2110 ENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQVDGVFVTLP---F 2162
+ FT+T+ + + +S+TL + +N +TL G +T P F
Sbjct: 457 DKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR--------GGQILTSPNQGF 508
Query: 2163 QLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAGSLCGLCGNYNQDPA 2219
L+ ++ LS +++ TT GL + F DG+ + +++ +A+ GLCG +N +
Sbjct: 509 NLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRRTLGLCGTFNGNIR 567
Query: 2220 DDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISA 2271
DD + G G W+V C V P PC QQ + G C VI
Sbjct: 568 DDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ-NIGYAAHCDVIHQ 624
Query: 2272 TDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD 2331
APCH + P Y+Q C DAC+ LC A+A Y C G + +
Sbjct: 625 E--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPIDFRTQIS 680
Query: 2332 FCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG--DTCVPVGQ 2389
FC C Y C C SC SLS+PE C C EGC C G + CVP+
Sbjct: 681 FCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPIFH 740
Query: 2390 CGCLHDDRYYPLGQTFYPGPG----------CDSLCR------CREG------------- 2420
C C + Y G+ G CD L C EG
Sbjct: 741 CRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPEL 800
Query: 2421 --GEVSCEPS--SCGPHETCRPSGGSL-GCVAVGST---------------TCQASGDPH 2460
G V+CE + + + TC PS + GCV C GD H
Sbjct: 801 PAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCPAVCTIYGDRH 860
Query: 2461 YTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFT 2520
Y +FDG +D++ C L ++ +V+ +N + + ++ + + V +
Sbjct: 861 YYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTE 916
Query: 2521 LRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGLRVAYDLVYYVRVTV 2579
+ L +K +G ++ + + G +V+ + + + +D + + V
Sbjct: 917 IYLNDTPYKQKQSGFFLE-----NKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKV 971
Query: 2580 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 2639
+ + GLCGN++ +D N + NA FG+SW +S P T P
Sbjct: 972 GPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCES---PDETIKP-- 1026
Query: 2640 EGCIPSEECPPELEK-KYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLG--G 2696
C K Y K+E C +L S +SC ++D K+C D C G
Sbjct: 1027 --------CEAHQNKFPYAKKE-CSILYSDI--FASCRNVIDVTSFAKNCHEDTCNCNLG 1075
Query: 2697 GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMEC 2733
G+ LC++I AY C G + WR+ T C ++C
Sbjct: 1076 GDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 313 bits (803), Expect = 2e-84
Identities = 309/1191 (25%), Positives = 473/1191 (39%), Gaps = 186/1191 (15%)
Query: 2833 PSGGI-LSCVNKDPCHGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHY 2882
PSG C+N G C TC Q G + +PN + C WG H+
Sbjct: 18 PSGSCPYECLN-----GAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHF 72
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAA 2940
+FDG + F G C+Y+ A C + + +TV N + G+ Y + +
Sbjct: 73 ETFDGIYYYFPGNCSYIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFS 127
Query: 2941 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV 3000
I I+ EI K NG+ LP ++ G+I + + A L+ FG +++D +
Sbjct: 128 NQEEIRIYGHEIKK---NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGI 182
Query: 3001 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 3060
+ L + G CGLCGN + ++D + I ++ SW D
Sbjct: 183 YLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLTPS 242
Query: 3061 SCPTCPEDRLEQYEGPGF-CGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 3119
P + +E F C L PF +CH ++ P + CV D+C D +
Sbjct: 243 DFPNPCSSGMPAFEAIFFKCQILLQF---PFLSCHEYIDPYLYIASCVNDLCKTDDD-ET 298
Query: 3120 LCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPA 3178
C+A Y AC AG I+DWR C C ++ + C CP +C T
Sbjct: 299 YCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEK 352
Query: 3179 VCEGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 3235
C G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 353 QCLGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVC 408
Query: 3236 GPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTC 3295
GG CT C PV +C GD H+ T DG + F G C
Sbjct: 409 V--GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMC 446
Query: 3296 EYLLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRK 3351
+Y+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 447 QYILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR----- 496
Query: 3352 LQVDGVFVTLP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYA 3405
G +T P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 ---GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWK 552
Query: 3406 GSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQ 3457
GLCG +N + DD + G G W+V C V P PC Q
Sbjct: 553 RRTLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQ 610
Query: 3458 QESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAA 3517
Q + G C VI APCH + P Y+Q C DAC+ LC A+A Y
Sbjct: 611 Q-NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYL 665
Query: 3518 CQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG 3577
C G + + FC C Y C C SC SLS+PE C C EGC C G
Sbjct: 666 CGQHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEG 725
Query: 3578 FVLSG--DTCVPVGQCGCLHDDRYYPLGQTFYPGPG----------CDSLCR------CR 3619
+ CVP+ C C + Y G+ G CD L C
Sbjct: 726 KFYEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICP 785
Query: 3620 EG---------------GEVSCEPS--SCGPHETCRPSGGSL-GCVAVGST--------- 3652
EG G V+CE + + + TC PS + GCV
Sbjct: 786 EGKEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCT 845
Query: 3653 ------TCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGR 3706
C GD HY +FDG +D++ C L ++ +V+ +N +
Sbjct: 846 YYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDND 901
Query: 3707 VSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFG 3765
+ ++ + + V + + L +K +G ++ + + G +V+ +
Sbjct: 902 IVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLE-----NKSTYQLWKAGYYIVVYFPEKD 956
Query: 3766 LRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVV 3825
+ + +D + + V + + GLCGN++ +D N + NA FG+SW
Sbjct: 957 ITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQ 1016
Query: 3826 PDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 3885
+S P T P A +K P Y K+E C +L S +SC ++D
Sbjct: 1017 CES---PDETIKPCEA---HQNKFP------YAKKE-CSILYSDI--FASCRNVIDVTSF 1061
Query: 3886 LKDCIFDLCLG--GGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMEC 3934
K+C D C GG+ LC++I AY C G + WR+ T C ++C
Sbjct: 1062 AKNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 307 bits (787), Expect = 2e-82
Identities = 308/1190 (25%), Positives = 459/1190 (38%), Gaps = 222/1190 (18%)
Query: 4048 HGVTCRPQETCKEQ-----GGQGVCLPNY----EATCWLWGDPHYHSFDGRKFDFQGTCN 4098
+G C TC Q G + +PN + C WG H+ +FDG + F G C+
Sbjct: 28 NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGICKTWGQYHFETFDGIYYYFPGNCS 87
Query: 4099 YVLATTGCPGVSTQGLTPFTVTTKNQNR--GNPAVSYVRVVTVAALGTNISIHKDEIGKV 4156
Y+ A C + + +TV N + G+ Y + + I I+ EI K
Sbjct: 88 YIFAKD-CGDLEPR----YTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRIYGHEIKK- 141
Query: 4157 RVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 4216
NG+ LP ++ G+I + + A L+ FG +++D + + L + G CGL
Sbjct: 142 --NGISLTLPQTI--GQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDHKGKSCGL 197
Query: 4217 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEG 4276
CGN + ++D + I ++ SW D C P D
Sbjct: 198 CGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-------KCVLTPSD------- 243
Query: 4277 PGFCGPLSSGTGG--------------PFTTCHAHVPPESFFKGCVLDVCMGGGDRDILC 4322
F P SSG PF +CH ++ P + CV D+C D + C
Sbjct: 244 --FPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDDD-ETYC 300
Query: 4323 KALASYVAACQAAGVVIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVC 4381
+A Y AC AG I+DWR C C ++ + C CP +C T C
Sbjct: 301 RAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTC------TFEKQC 354
Query: 4382 EGP---CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 4438
G C++GC C G V+ C+ L N C C +G + GS+ + C++ C C
Sbjct: 355 LGSNLHCLDGCYCPDGLVMDNGTCISLEN-CPCGFHGLAYSVGSKI--EQECTE-CVCV- 409
Query: 4439 GGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY 4498
GG CT C PV +C GD H+ T DG + F G C+Y
Sbjct: 410 -GGVWNCTEQDC-----------------PV---QCSVVGDSHFTTFDGRHYSFIGMCQY 448
Query: 4499 LLSAPCHGPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQI---YNHSLTLSARWPRKLQ 4554
+L G + FT+T+ + + +S+TL + +N +TL
Sbjct: 449 ILVKGT-----GKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGR------- 496
Query: 4555 VDGVFVALP---FQLDSLLHAH-LSGADVVVTTTSGLSLAF--DGDSFVRLRVPAAYAAS 4608
G + P F L+ ++ LS +++ TT GL + F DG+ + +++ +A+
Sbjct: 497 -GGQILTSPNQGFNLNGIVEIQTLSSLFILLKTTFGLKILFAIDGER-IYIQLTSAWKRR 554
Query: 4609 LCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPCTPEQQE 4660
GLCG +N + DD + G G W+V C V P PC QQ
Sbjct: 555 TLGLCGTFNGNIRDDFLSPSGMIEGTPQLHANAWRVSST--CFAPVHVPVVDPCNINQQ- 611
Query: 4661 SFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQ 4720
+ G C VI APCH + P Y+Q C DAC+ LC A+A Y C
Sbjct: 612 NIGYAAHCDVIHQE--LFAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCG 667
Query: 4721 AAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG-- 4778
G + + FC + C Y C C SC SLS+PE C C EGC C G
Sbjct: 668 QHGVPIDFRTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKF 727
Query: 4779 FVLSGDTCVPVGQCGCLHDGRYYPLGEVF------------------------------- 4807
+ + + CVP+ C C + G Y GE+
Sbjct: 728 YEDTLNFCVPIFHCRCHYRGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEG 787
Query: 4808 -------YPGPE-------CERRC-------ECGPGGHVTCQEGAACGPHEECRLEDGVQ 4846
+P PE CE C C P C G C P CR G+
Sbjct: 788 KEYFDCRFPDPELPAGGVNCETTCANLAMNFTCTPSS--PCISGCVCAP-GVCR--RGMF 842
Query: 4847 ACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAG 4905
C C C G HY + DG YD C L + D D S++ +
Sbjct: 843 NCTYYPCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIK----SADDSDISVIAQNKKCF 898
Query: 4906 DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRN-----------MVL 4954
D +V ++S+ + D P + E ++ +V
Sbjct: 899 DND--IVCSKSVLISVGDTEIYLND-----TPYKQKQSGFFLENKSTYQLWKAGYYIVVY 951
Query: 4955 QTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAA 5014
K + +L+D + + + ++ +L GLCGNF+ S+D N + FG +
Sbjct: 952 FPEKDITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDS 1011
Query: 5015 WRAPGSSKGCGEGCGPQGCPVCLAEETA-PYESNEACGQLRNPQGPFATCQAVLSPSEYF 5073
W A G + E P C A + PY E C L + FA+C+ V+ + +
Sbjct: 1012 W-ALGQCESPDETIKP-----CEAHQNKFPYAKKE-CSILYS--DIFASCRNVIDVTSFA 1062
Query: 5074 RQCVYDLCAQK--GDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
+ C D C GD LC S+AAY C G+++ WR+ + C L C
Sbjct: 1063 KNCHEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 306 bits (783), Expect = 5e-82
Identities = 293/1182 (24%), Positives = 468/1182 (39%), Gaps = 143/1182 (12%)
Query: 820 CQRRCTCNGA--THQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDG 877
C C NGA + TC + G RC + + R G C+ G H+ +FDG
Sbjct: 22 CPYECL-NGAFCSKTGTCDCQIFQALGTRCQIIPNMGN---GRDGICKTWGQYHFETFDG 77
Query: 878 RRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHR--GSQTVSYTRAVRVEARGVKVAVR 935
+ F G C+Y+ CG P + V V N + GS Y + ++ +
Sbjct: 78 IYYYFPGNCSYIFAKDCGDLE--PRYTVWVHNSPKCLGSVYSCYRSISLFFSNQEEIRI- 134
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSY 995
Y ++ + + LP GQ+ + + +V+T FG ++ +D + + K+ +
Sbjct: 135 --YGHEIKKNGISLTLP--QTIGQIFIEKLADYILVKTTFGFSLAWDGISGIYLKLSEDH 190
Query: 996 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPG--CGATEPGDCPKLDS 1053
CGLCGN+N +DD + + F NSW +T C T P D P S
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCVLT-PSDFPNPCS 249
Query: 1054 LVAQQLQS-KNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATY 1112
++ +C IL + PF CH +DP + CV D C C A Y
Sbjct: 250 SGMPAFEAIFFKCQILL--QFPFLSCHEYIDPYLYIASCVNDLCKTDDDE-TYCRAATEY 306
Query: 1113 AAACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCV 1171
A AC AG + WR + C C + C CP +C G C +GC
Sbjct: 307 ARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLGSNLHCLDGCY 366
Query: 1172 CDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGP 1231
C +G + +C+ L +C C G + G C C C GG+ +C C
Sbjct: 367 CPDGLVMDNGTCISLENCPCGFHGLAYSVGSKI--EQECTE-CVC-VGGVWNCTEQDC-- 420
Query: 1232 HEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRF 1291
C GD H+TTFDGR + F+G C Y+L + GT G +F
Sbjct: 421 -----------------PVQCSVVGDSHFTTFDGRHYSFIGMCQYILVK--GT--GKDKF 459
Query: 1292 AV-LQENVAWGN-GRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRA 1349
+ LQ+ N G V + + + +F ++ + + + + NG +
Sbjct: 460 TITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNL---NGIVEI 516
Query: 1350 SQHGS-DVVIETDFGLRVAYDL---VYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPN 1405
S ++++T FGL++ + + Y+++T + ++ GLCG +NG+ +DDF P+
Sbjct: 517 QTLSSLFILLKTTFGLKILFAIDGERIYIQLT--SAWKRRTLGLCGTFNGNIRDDFLSPS 574
Query: 1406 GSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLS 1465
G G N+W S C P P I ++ C ++
Sbjct: 575 GMIEGTPQLHANAWR---VSSTCFAPVHVPVVDPCNIN--------QQNIGYAAHCDVIH 623
Query: 1466 SPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTE 1525
+ CH + P + C D C G S LC+ + Y C G ++ +RT+
Sbjct: 624 QEL--FAPCHIYISPGLYYQLCRHDACKCGS--SCLCNALAHYAYLCGQHGVPID-FRTQ 678
Query: 1526 -TFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNG--QACVPI 1582
+FC + C Y C+ C C +LS+P QC D CAEGC C G Y CVPI
Sbjct: 679 ISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFCVPI 738
Query: 1583 QQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE-------HSCKPGQV---CQ- 1631
C C++ G Y+P + LI C C G + C E H C G+ C+
Sbjct: 739 FHCRCHYRGSVYQPGE--LIPTPSGLCQCSNGT-VKCDELATPSAVHICPEGKEYFDCRF 795
Query: 1632 -----PSGGI------------LSCVTKDPC-HGVTCRPQETCKEQGGQGVCLPNYEATC 1673
P+GG+ +C PC G C P C+ +G A C
Sbjct: 796 PDPELPAGGVNCETTCANLAMNFTCTPSSPCISGCVCAP-GVCR-RGMFNCTYYPCPAVC 853
Query: 1674 WLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVR 1733
++GD HY+SFDG ++D+ C L + + + +V +N+ + + +
Sbjct: 854 TIYGDRHYYSFDGLEYDYISDCQVFL-------IKSADDSDISVIAQNKKCFDNDIVCSK 906
Query: 1734 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQ 1790
V ++ T I ++ D K + +G + + + + +V F +
Sbjct: 907 SVLISVGDTEIYLN-DTPYKQKQSGFF-------LENKSTYQLWKAGYYIVVYFPEKDIT 958
Query: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
+ +D + + + + + GLCGN D+ +ND N + ++G SW
Sbjct: 959 ILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW------ 1012
Query: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 1910
+C T Q + P + F +C + SF K C D C
Sbjct: 1013 --ALGQCESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTC 1070
Query: 1911 MG--GGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITC 1950
GGD + LC ++A+Y C G+ I WR+ C + C
Sbjct: 1071 NCNLGGDCECLCTSIAAYAYKCCQEGISIH-WRSSTVCSLDC 1111
Score = 254 bits (648), Expect = 2e-66
Identities = 226/841 (26%), Positives = 342/841 (40%), Gaps = 99/841 (11%)
Query: 4424 FWADGTCSQWCRCGPGGGSLVCTPASC------GLGEVCGLLPSGQHGCQPVSTAECQAW 4477
F G+C C G+ +C LG C ++P+ +G + C+ W
Sbjct: 16 FSPSGSCPYECL----NGAFCSKTGTCDCQIFQALGTRCQIIPNMGNGRDGI----CKTW 67
Query: 4478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAV-SYTRSVTL 4536
G H+ T DG + F G C Y+ + C +TV V N + +V S RS++L
Sbjct: 68 GQYHFETFDGIYYYFPGNCSYIFAKDCGDLE---PRYTVWVHNSPKCLGSVYSCYRSISL 124
Query: 4537 QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 4596
N + +++ +G+ + LP + + L+ ++V TT G SLA+DG S
Sbjct: 125 FFSNQEEIRI--YGHEIKKNGISLTLPQTIGQIFIEKLADY-ILVKTTFGFSLAWDGISG 181
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSK 4648
+ L++ + CGLCGNYN +DD + + W V +CV
Sbjct: 182 IYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDT-KCVLT 240
Query: 4649 PC--PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPG 4706
P P+PC+ C ++ P CH + P Y C+ D C+
Sbjct: 241 PSDFPNPCSSGMPAFEAIFFKCQIL--LQFPFLSCHEYIDPYLYIASCVNDLCKTDDDET 298
Query: 4707 GLCPAVATYVAACQAAGAQLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEG 4764
C A Y AC AG + +WR DF C +C + C CP +C G
Sbjct: 299 -YCRAATEYARACSHAGYPIQDWR-DDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCLG 356
Query: 4765 CESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGH 4824
C +GC C G V+ TC+ + C C G Y +G + E+ C
Sbjct: 357 SNLHCLDGCYCPDGLVMDNGTCISLENCPCGFHGLAYSVGS------KIEQECT------ 404
Query: 4825 VTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDLHGSCSYVLA 4883
EC GV C C +C G H+ T DGR Y G C Y+L
Sbjct: 405 -------------ECVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILV 451
Query: 4884 QVCHPKPGDEDFSIVLEKNAAGD------LQRLLVTVA---GQVVSLAQGQQV-TVDGEA 4933
+ G + F+I L+K LQ + + + + V+L +G Q+ T +
Sbjct: 452 K----GTGKDKFTITLQKAPCEQNLGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQG 507
Query: 4934 VALPVAVGRVRV-TAEGRNMVLQTTKGLRLLF--DGDAHLLMSIPSPFRGRLCGLCGNFN 4990
L G V + T ++L+TT GL++LF DG+ + + + S ++ R GLCG FN
Sbjct: 508 FNLN---GIVEIQTLSSLFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFN 563
Query: 4991 GNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEAC 5050
GN DDF+ P+G + + AWR SS P P + ++ Y ++ C
Sbjct: 564 GNIRDDFLSPSGMIEGTPQLHANAWRV--SSTCFAPVHVPVVDPCNINQQNIGYAAH--C 619
Query: 5051 GQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKP 5110
+ Q FA C +SP Y++ C +D C K + LC +LA Y C GV +
Sbjct: 620 DVIH--QELFAPCHIYISPGLYYQLCRHDAC--KCGSSCLCNALAHYAYLCGQHGVPIDF 675
Query: 5111 WRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQ--GVC 5168
SFC + C Y C+ C SC +LS C+ C EGC C + C
Sbjct: 676 RTQISFCAVVCQKGMLYHHCSSFCLHSCISLSSPEQCSDDCAEGCNCPEGKFYEDTLNFC 735
Query: 5169 IPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG-RVCEVKAEARN 5227
+P+ C C + G + T S C CS+ + + C P +C E +
Sbjct: 736 VPIFHCRCHYRGSVYQPGELIPTP--SGLCQCSNGT-VKCDELATPSAVHICPEGKEYFD 792
Query: 5228 C 5228
C
Sbjct: 793 C 793
Score = 201 bits (512), Expect = 1e-50
Identities = 195/769 (25%), Positives = 303/769 (39%), Gaps = 120/769 (15%)
Query: 455 CQVVGGKAGCVAESTAV-CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C VGG C + V C GD H+TTFDGR Y +G C Y +V+ +D
Sbjct: 406 CVCVGGVWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQK 465
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVD-NQRSRLPVSLSEGRLRVYQ 572
++ G + + L+ ++ V+L RG G +L NQ L + L
Sbjct: 466 APCEQNLGLVCLQSITLILEDDFNKQVTLGRG--GQILTSPNQGFNLNGIVEIQTL---- 519
Query: 573 SGPRAVVELVFGLVVTYDWDCQ-LALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAP 631
S +++ FGL + + D + + + L + ++ + GLCG +NG+ DDFL+P G +
Sbjct: 520 SSLFILLKTTFGLKILFAIDGERIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEG 579
Query: 632 DAVEFASSWKLDDGDYL-----CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAV 686
A++W++ + D C N G A H C ++ + FA
Sbjct: 580 TPQLHANAWRVSSTCFAPVHVPVVDPCNINQQNI--GYAAH------CDVIHQ--ELFAP 629
Query: 687 CHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPAN-CPLSC 745
CH + P + + C +D C G LC L+ YA C + G+ + D+R+ + C + C
Sbjct: 630 CHIYISPGLYYQLCRHDACKCGSS--CLCNALAHYAYLCGQHGVPI-DFRTQISFCAVVC 686
Query: 746 PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG--FVASGGACVPASSCGCTF 803
Y C C SC ++P CS C EGC C G + + CVP C C +
Sbjct: 687 QKGMLYHHCSSFCLHSCISLSSPEQCSD-DCAEGCNCPEGKFYEDTLNFCVPIFHCRCHY 745
Query: 804 QGLQLAPGQ--------------EVWADELCQRRC------------------------- 824
+G PG+ V DEL
Sbjct: 746 RGSVYQPGELIPTPSGLCQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGV 805
Query: 825 ----TCNGATHQVTCRDKQSCPAGERCS---VQNGLLGC--YPDRFGTCQGSGDPHYVSF 875
TC TC C +G C+ + G+ C YP C GD HY SF
Sbjct: 806 NCETTCANLAMNFTCTPSSPCISGCVCAPGVCRRGMFNCTYYPCP-AVCTIYGDRHYYSF 864
Query: 876 DGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVR 935
DG +D++ C L+ S + V+ +N+ + +++V + ++ +
Sbjct: 865 DGLEYDYISDCQVFLIKSADDSD----ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLN 920
Query: 936 REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSS 994
Q Q F Q+++ G VV + +T+ +D + KV
Sbjct: 921 DTPYKQK------QSGFFLENKSTYQLWKAGYYIVVYFPEKDITILWDRKTTIHIKVGPQ 974
Query: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSL 1054
+ L GLCGNF+ ++D+ + NA FG+SW G C D
Sbjct: 975 WKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSW-----------ALGQCESPDET 1023
Query: 1055 V----AQQLQ---SKNECGILADPKGPFRECHSKLDPQGAVRDCVYD--RCLLPGQSGPL 1105
+ A Q + +K EC IL F C + +D ++C D C L G L
Sbjct: 1024 IKPCEAHQNKFPYAKKECSILY--SDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081
Query: 1106 CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSH------YEACSYG 1148
C ++A YA C G ++H WRS +C L C ++ Y SYG
Sbjct: 1082 CTSIAAYAYKCCQEGISIH-WRSSTVCSLDCEYYNEGLGEGPYMLASYG 1129
Score = 85.5 bits (210), Expect = 1e-15
Identities = 97/406 (23%), Positives = 143/406 (35%), Gaps = 47/406 (11%)
Query: 464 CVAESTAVCRAQ--GDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRG 521
C E CR + TFDG + SY +V + E + A +
Sbjct: 1431 CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGE--IIVAHIEKCSMNQAP 1488
Query: 522 SRRVSYVGL--VTVRAYSHSVSLTR----GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGP 575
S R+S + + V H + + R EV ++V P+ S L + SG
Sbjct: 1489 SGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVV-------PLPFSSQELSIEDSGS 1541
Query: 576 RAVVELVFGLVVTYDW---DCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPD 632
V+ GL++ + + GLCG N DP DD +G + +
Sbjct: 1542 MYVITTPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITN 1601
Query: 633 AVE---FASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
+ F SW+++ + NC Q R+ F CHD
Sbjct: 1602 MEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCSQCIDLLNRRI----------FIPCHD 1651
Query: 690 TLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANS 749
+ P F E+ + C LSAY C + I + WR+P C LSCP
Sbjct: 1652 KVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGK 1707
Query: 750 RYELCGPACPT-SCNGAAAPSNCSGRPCVEGCVCLPGFV---ASGGACVPASSCGCTFQG 805
Y+ C C +C + S E CVC G + C+P C CT
Sbjct: 1708 EYQPCVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSE 1767
Query: 806 LQLAPGQEVW---ADELCQRRCTCNGATHQV--TCRDKQSCPAGER 846
Q E+W DE +C NG+ + C D++ P ER
Sbjct: 1768 DQPRTAGEIWNGGIDECTLYKCLENGSIIPIEPDC-DEEPTPVCER 1812
Score = 81.3 bits (199), Expect = 2e-14
Identities = 95/389 (24%), Positives = 145/389 (37%), Gaps = 47/389 (12%)
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2130
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2131 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2190
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 2191 G-----DSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 2233
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 2234 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 2292
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 2293 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPG 2352
++ + C A++ YVA C + +WR PD+C CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 2353 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGCL-HDDRYYPLGQTFY 2406
G S RE CVC G +L C+P +C C +D+ G+ +
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWN 1778
Query: 2407 PGPGCDSLCRCREGGEVSCEPSSCGPHET 2435
G +L +C E G + C T
Sbjct: 1779 GGIDECTLYKCLENGSIIPIEPDCDEEPT 1807
Score = 81.3 bits (199), Expect = 2e-14
Identities = 95/389 (24%), Positives = 145/389 (37%), Gaps = 47/389 (12%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 3331
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 3332 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 3391
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 3392 G-----DSFVRLRVP-AAYAGSLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 3434
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 3435 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 3493
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 3494 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPG 3553
++ + C A++ YVA C + +WR PD+C CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 3554 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGCL-HDDRYYPLGQTFY 3607
G S RE CVC G +L C+P +C C +D+ G+ +
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPRTAGEIWN 1778
Query: 3608 PGPGCDSLCRCREGGEVSCEPSSCGPHET 3636
G +L +C E G + C T
Sbjct: 1779 GGIDECTLYKCLENGSIIPIEPDCDEEPT 1807
Score = 79.0 bits (193), Expect = 1e-13
Identities = 100/440 (22%), Positives = 165/440 (37%), Gaps = 73/440 (16%)
Query: 4818 ECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGS 4877
+CG G C P EC RC + IT DG L+
Sbjct: 1416 DCGFRGRPVQVNSDICCPEWECPC-------------RCSMLSELSIITFDGNNAALYSM 1462
Query: 4878 CSYVLAQVCHPKPGDEDFSIV----LEKNAAGDLQRL------LVTVAGQVVSLAQGQQV 4927
SY+L ++ PG+ + + + + +G + L + T +++ ++V
Sbjct: 1463 ASYILVRI----PGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKV 1518
Query: 4928 TVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL--LMSIPSPFRGRLC-- 4983
VD V LP + + + G V+ T GL + + +HL ++ I FR L
Sbjct: 1519 EVDSIVVPLPFSSQELSIEDSGSMYVITTPAGLIIKW---SHLTGIIDIHFGFRFNLSSY 1575
Query: 4984 --GLCGNFNGNWSDDFVLPNGSAASSVETFGA---AWRAPGS----SKGCGEGCGPQGCP 5034
GLCG N + DD + NG+ +++E G +W S + C C
Sbjct: 1576 TEGLCGICNEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTMRRPVRNCTEHDCS 1635
Query: 5035 VCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSL 5094
C+ L N + F C +SP ++ + + + C +L
Sbjct: 1636 QCI--------------DLLNRR-IFIPCHDKVSPEDFCEKMWINYTYFWN---YECDAL 1677
Query: 5095 AAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT--RCF 5152
+AY A C + ++ WRT +C L CP Y C R C+ G T+
Sbjct: 1678 SAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLNLR 1736
Query: 5153 EGCECDDRFLLSQ---GVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCS---CSSSSGL 5206
E C C +L + CIP ++C CT + P + + + + C+ C + +
Sbjct: 1737 EDCVCKVGTILHRPHSAQCIPEKECACT-DSEDQPRTAGEIWNGGIDECTLYKCLENGSI 1795
Query: 5207 TCQAAGC--PPGRVCEVKAE 5224
C P VCE +AE
Sbjct: 1796 IPIEPDCDEEPTPVCEREAE 1815
Score = 78.6 bits (192), Expect = 2e-13
Identities = 95/400 (23%), Positives = 146/400 (36%), Gaps = 56/400 (14%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C + ++FDG +Y+LV G+ + + G + + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDW 983
V K+ V R +V VD ++ LPF + + ++ G V+ T GL + +
Sbjct: 1501 NVTTPIHKIIVNR-LARKVEVDSIVVPLPFSSQELSIE--DSGSMYVITTPAGLIIKW-- 1555
Query: 984 NARVTAKVP---------SSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFG---NS 1031
+ +T + SSY E LCG+C N DP DDL ++ G N G S
Sbjct: 1556 -SHLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIES 1611
Query: 1032 WQEET-------RPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDP 1084
W+ E RP TE DC + L+ +++ F CH K+ P
Sbjct: 1612 WEIEKSFEVTMRRPVRNCTEH-DCSQCIDLLNRRI---------------FIPCHDKVSP 1655
Query: 1085 QGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEA 1144
+ + CDAL+ Y A C + WR+ + C LSCP Y+
Sbjct: 1656 EDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQP 1711
Query: 1145 CSYGCPL-SCGDLPVPGGCGS-ECHEGCVCDEGFAL---SGESCLPLASCGCV-HQGTYH 1198
C C +C + G E CVC G L C+P C C +
Sbjct: 1712 CVRPCEARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 1199 PPGQTFYPGPGCDSLCHCQEGGLVSCESSSCG--PHEACQ 1236
G+ + G +L C E G + C P C+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPIEPDCDEEPTPVCE 1811
Score = 77.8 bits (190), Expect = 3e-13
Identities = 87/345 (25%), Positives = 130/345 (37%), Gaps = 46/345 (13%)
Query: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLL-SAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 4532
C + +T DG+ Y+L P E ++ A R S
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 4533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 4592
+VT I H + ++ R RK++VD + V LPF L SG+ V+TT +GL + +
Sbjct: 1501 NVTTPI--HKIIVN-RLARKVEVDSIVVPLPFSSQEL-SIEDSGSMYVITTPAGLIIKWS 1556
Query: 4593 G-----DSFVRLRVP-AAYAASLCGLCGNYNQDPADDLKAVGGKPA-----------GWQ 4635
D R ++Y LCG+C N+DP DDL+ G W+
Sbjct: 1557 HLTGIIDIHFGFRFNLSSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWE 1613
Query: 4636 VGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPL-APCHGLVPPAQYFQGC 4694
+ + E + CT D I + + PCH V P + +
Sbjct: 1614 I---EKSFEVTMRRPVRNCTEH--------DCSQCIDLLNRRIFIPCHDKVSPEDFCEKM 1662
Query: 4695 LLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPV 4754
++ + C A++ YVA C + +WR PD+C L CP Y+ C C
Sbjct: 1663 WINYTYFWNYE---CDALSAYVALCNKFDICI-QWRTPDYCSLSCPEGKEYQPCVRPCEA 1718
Query: 4755 SCPSLSAPEGCESA--CREGCVCDAGFVL---SGDTCVPVGQCGC 4794
G S RE CVC G +L C+P +C C
Sbjct: 1719 RTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 65.9 bits (159), Expect = 1e-09
Identities = 90/390 (23%), Positives = 141/390 (36%), Gaps = 56/390 (14%)
Query: 1659 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 1716
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 1717 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 1771
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 1772 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 1822
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 1823 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 1879
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 1880 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 1939
L F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 1940 WRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 1996
WR C ++CPE Y+ C PC A C E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPH 1751
Query: 1997 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 2026
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 65.9 bits (159), Expect = 1e-09
Identities = 90/390 (23%), Positives = 142/390 (36%), Gaps = 56/390 (14%)
Query: 4061 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 4118
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 4119 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 4173
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 4174 ISVAQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 4224
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 4225 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 4281
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 4282 PLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 4341
L + F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLLNRR--IFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 4342 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 4398
WR C ++CPE Y+ C PC A C E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPH 1751
Query: 4399 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 65.5 bits (158), Expect = 1e-09
Identities = 90/390 (23%), Positives = 141/390 (36%), Gaps = 56/390 (14%)
Query: 2860 QGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 2917
Q +C P +E C + + +FDG +Y+L PG
Sbjct: 1425 QVNSDICCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRI--PG-------EII 1475
Query: 2918 VTTKNQNRGNPAVS-YVRVVTVAALGTNISIHKDEIG----KVRVNGVLTALPVSVADGR 2972
V + N A S + + L IHK + KV V+ ++ LP S +
Sbjct: 1476 VAHIEKCSMNQAPSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQE-- 1533
Query: 2973 ISVTQGASKALLVADFGLQVSYD---------WNWRVDVTLPSSYHGAVCGLCGNMDRNP 3023
+S+ S ++ GL + + + +R ++ SSY +CG+C + +P
Sbjct: 1534 LSIEDSGSMYVITTPAGLIIKWSHLTGIIDIHFGFRFNL---SSYTEGLCGIC---NEDP 1587
Query: 3024 NNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCG 3080
++D NGT+ + I ++ SW + R C E Q C
Sbjct: 1588 DDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVTM---RRPVRNCTEHDCSQ------CI 1638
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L F CH V PE F + ++ C AL++YVA C + I+
Sbjct: 1639 DLL--NRRIFIPCHDKVSPEDFCEKMWINYTYFWNYE---CDALSAYVALCNKFDICIQ- 1692
Query: 3141 WRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVL---S 3197
WR C ++CPE Y+ C PC A C E C C G +L
Sbjct: 1693 WRTPDYCSLSCPEGKEYQPCVRPCEARTCLNQWFYGHTSCLN-LREDCVCKVGTILHRPH 1751
Query: 3198 ADRCVPLNNGCGCWANGTYHEAGSEFWADG 3227
+ +C+P C C + E W G
Sbjct: 1752 SAQCIP-EKECACTDSEDQPRTAGEIWNGG 1780
Score = 59.3 bits (142), Expect = 1e-07
Identities = 112/530 (21%), Positives = 177/530 (33%), Gaps = 113/530 (21%)
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGF--ALSGESC 1183
WR E C C ++ CS L+C LP GC C + + DE + C
Sbjct: 1279 WRYEP-CATPC-----FKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDC 1332
Query: 1184 LPLASCGCVHQGTYHPPGQTFYP-----------------------GPGC-----DSLCH 1215
+P+ + T PP + P G C D +
Sbjct: 1333 IPVIPT----EPTLMPPAKPTVPMFTVWEMITPSDITVFDMLTPTTGLECEPQKFDPVYD 1388
Query: 1216 CQEGGLVSCE------SSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDP 1258
C + ++ E S +C P + P G G C C+ S +
Sbjct: 1389 CSQYICLNMEWQLYNWSLNC-PKDVEMPDCGFRGRPVQVNSDICCPEWECPCRCSMLSEL 1447
Query: 1259 HYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 1318
TFDG Y+L + G H G + + V
Sbjct: 1448 SIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKLNVTTPIH 1507
Query: 1319 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY-------DLV 1371
+ + + KV V+ + + LP ++ ++ GS VI T GL + + D+
Sbjct: 1508 KIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHLTGIIDIH 1565
Query: 1372 YYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWE-----EVV 1423
+ R + +Y + +CG+C N DP DD + NG+ N + G SWE EV
Sbjct: 1566 FGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEIEKSFEVT 1621
Query: 1424 PDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 1483
P T DC +C L ++ CH V P+
Sbjct: 1622 MRRPVRNCT-----EHDC---SQCIDLLNRRI---------------FIPCHDKVSPEDF 1658
Query: 1484 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCAD 1543
+ + + C + AYV+ C ++ WRT +C + CP Y+ C
Sbjct: 1659 CEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPCVR 1714
Query: 1544 TCSLGCSALSAPPQCQDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 1587
C + L+ C E C C G + + C+P ++C C
Sbjct: 1715 PCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 58.5 bits (140), Expect = 2e-07
Identities = 84/422 (19%), Positives = 145/422 (34%), Gaps = 58/422 (13%)
Query: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 2512
C + TFDG Y+L + G H G + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 2513 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY--- 2569
V + + + KV V+ + + LP ++ ++ GS VI T GL + +
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 2570 ----DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWEE 2622
D+ + R + +Y + +CG+C N DP DD + NG+ N + G SWE
Sbjct: 1559 TGIIDIHFGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 2623 VVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQ 2682
+ P C +C L ++ CH V P+
Sbjct: 1615 EKSFEVTMRRPVRNCTEHDC---SQCIDLLNRRI---------------FIPCHDKVSPE 1656
Query: 2683 GPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELC 2742
+ + + C + AYV+ C ++ WR +C + CP+ Y+ C
Sbjct: 1657 DFCEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPC 1712
Query: 2743 ADTCSLGCSALSAPLQCPDGC---AEGCQCDSGFLY---NGQACVPIQQCGCYHNGAYYE 2796
C + L+ C E C C G + + C+P ++C C +
Sbjct: 1713 VRPCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECACTDSEDQPR 1771
Query: 2797 PEQTVL---IDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGIL-------SCVNKD 2844
+ ID C G ++ E C +P VC+ ++ +C +K+
Sbjct: 1772 TAGEIWNGGIDECTLYKCLENGSIIPI-EPDCDEEPTPVCEREAEVVMGIIDKWTCCSKE 1830
Query: 2845 PC 2846
C
Sbjct: 1831 VC 1832
Score = 57.4 bits (137), Expect = 4e-07
Identities = 72/352 (20%), Positives = 123/352 (34%), Gaps = 45/352 (12%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713
C + TFDG+ Y+L + G H G + +
Sbjct: 1441 CSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAHIEKCSMNQAPSGRISGLCFKKL 1500
Query: 3714 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY--- 3770
V + + + KV V+ + + LP ++ ++ GS VI T GL + +
Sbjct: 1501 NVTTPIHKIIVNRLARKVEVDSIVVPLP--FSSQELSIEDSGSMYVITTPAGLIIKWSHL 1558
Query: 3771 ----DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFG---NSWEE 3823
D+ + R + +Y + +CG+C N DP DD + NG+ N + G SWE
Sbjct: 1559 TGIIDIHFGFRFNL-SSYTEGLCGIC---NEDPDDDLRMQNGTIITNMEDIGLFIESWEI 1614
Query: 3824 VVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQ 3883
+ P C +C L ++ CH V P+
Sbjct: 1615 EKSFEVTMRRPVRNCTEHDC---SQCIDLLNRRI---------------FIPCHDKVSPE 1656
Query: 3884 GPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELC 3943
+ + + C + AYV+ C ++ WR +C + CP+ Y+ C
Sbjct: 1657 DFCEKMWINYTYFW---NYECDALSAYVALCNKFDICIQ-WRTPDYCSLSCPEGKEYQPC 1712
Query: 3944 ADTCSLGCSALSAPLQCPDGC---AEGCQCDSGFLY---NGQACVPIQQCGC 3989
C + L+ C E C C G + + C+P ++C C
Sbjct: 1713 VRPCE-ARTCLNQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763
Score = 47.0 bits (110), Expect = 5e-04
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 5193 DCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGA 5252
+C CS + CQ G C++ N G+C + TFDG
Sbjct: 25 ECLNGAFCSKTGTCDCQIFQAL-GTRCQIIPNMGN--GRDGICKTWGQYHFETFDGIYYY 81
Query: 5253 TTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH-------IFFQDGMVTL 5305
Y + C L+ P Y V H + +G V+ +FF +
Sbjct: 82 FPGNCSYIFAKDCGDLE---PRYTVWV-----HNSPKCLGSVYSCYRSISLFFSNQEEIR 133
Query: 5306 TPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQV-WLGANGKVAVIVSNDH 5364
+ NG+ + LP + + + + + D +LV+ G + W G +G + + +S DH
Sbjct: 134 IYGHEIKKNGISLTLP-QTIGQIFIEKLAD-YILVKTTFGFSLAWDGISG-IYLKLSEDH 190
Query: 5365 AGKLCGACGNFDGDQTNDWHDSQE 5388
GK CG CGN++ Q++D+ QE
Sbjct: 191 KGKSCGLCGNYNDIQSDDFIILQE 214
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 311 bits (796), Expect = 1e-83
Identities = 329/1243 (26%), Positives = 475/1243 (38%), Gaps = 185/1243 (14%)
Query: 858 PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 917
PD+ G C G H+ +FD +DF GTC Y+ +C A P F V + GS +
Sbjct: 40 PDK-GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD--AFPTFSVQLRRGPDGSIS- 95
Query: 918 SYTRAVRVEARGVKVAVRREYPGQVLVDDV-LQYLPFQAADGQVQVFRQGRDAVVRT-DF 975
+ VE V V + V D+ + LP+ + Q+ F Q V + +
Sbjct: 96 ----RIIVELGASVVTVSEAI---ISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLEL 148
Query: 976 GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE 1035
L V + ++ + V Y +CGLCGNF+G ++ G + F + Q+
Sbjct: 149 ELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFA-ALQKL 206
Query: 1036 TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDR 1095
PG E + S +Q Q C L P EC +P V C D
Sbjct: 207 DDPG----EICTFQDIPSTHVRQAQHARICTQLLTLVAP--ECSVSKEP--FVLSCQADV 258
Query: 1096 CLLPGQSGPL---CDALATYAAACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPL 1151
P Q GP C L+ Y+ C G V WRS LC + CP + Y+ C C
Sbjct: 259 AAAP-QPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVK 317
Query: 1152 SCGDLPVPGGCGSECHEGCVCDEGFALS----GESCLPLASCGCVHQGTYHPPGQTFYPG 1207
+C + C S C GC C EG L+ +C+P+ C CV G + PG+
Sbjct: 318 TCSN--PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAA 375
Query: 1208 PGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRR 1267
C + C C G V C C H C G TTFD R
Sbjct: 376 --CQT-CRCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARP 412
Query: 1268 FDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQW 1327
+ F GTC Y+L Q+ AV ++ G + V V ++ + +
Sbjct: 413 YRFHGTCTYILLQSPQLPEDGALMAVYDKS---GVSHSETSLVAVVYLSRQDKIVISQDE 469
Query: 1328 KVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQQ 1385
VT NG LP N + Q + + + T FGL + L ++ VTV + Q
Sbjct: 470 VVTNNGEAKWLPYKTRNITV-FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQ 528
Query: 1386 MCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSH 1445
GLCGN+NGD DDF G G A+ F +SW CP E +
Sbjct: 529 TRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA----------GNCPAALER--ETD 576
Query: 1446 KCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNI 1505
C K E C +L CH V+P K C++ C +C+ +
Sbjct: 577 PCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAAL 636
Query: 1506 HAYVSACQAAGGHVEPWRTETF-CPMECPPNSHYELCADTCSLGCSALS-APPQCQDGCA 1563
YV AC G + WR+ C + C N+ + + C C +LS +C
Sbjct: 637 GDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAV 696
Query: 1564 --EGCQCDSGFLYNGQA-CVPIQQCGCYHNGV-YYEPEQTVLIDNCRQQC---------- 1609
+GC C G N + CV QC C G + EQ+ +I+ C
Sbjct: 697 PVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQR 756
Query: 1610 ------TCHAGK--------------------------GMVCQEHSCKPGQVCQPS---G 1634
+C A K G+ C C+PG VC
Sbjct: 757 PQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYEN 816
Query: 1635 GILSCVTKDPC----HGVT----------CRPQETCKEQGGQGVCLPNYE--ATCWLWGD 1678
CV + C GV+ CR TC G+ C +TC L+G+
Sbjct: 817 ADGQCVPPEECPCEFSGVSYPGGAELHTDCR---TCSCSRGRWACQQGTHCPSTCTLYGE 873
Query: 1679 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 1738
H +FDG++F F G C Y+LAT C GV+ T F + T+N GN V+ R + +
Sbjct: 874 GHVITFDGQRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIF 931
Query: 1739 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWR 1798
G ++ + V G + + V G +S+ S + + L + ++ +
Sbjct: 932 LGGLSVVLAD---RNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRHMT 985
Query: 1799 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 1858
+ + + + +CGLCGN + N +D + +A S SW+ PLC D
Sbjct: 986 ILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGDVSF 1042
Query: 1859 GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDR 1916
+ P C + + C + T F TCH+ V +++ CV D C GGD
Sbjct: 1043 VTDP-CSLNAFRRSWAERKCSVINSQT---FATCHSKVYHLPYYEACVRDACGCDSGGDC 1098
Query: 1917 DILCKALASYVAACQAAGVVIEDWRAQVGCEITC------PENSHYE---VCGSPC---- 1963
+ LC A+A+Y AC GV + DWR C I C ++ H E + C
Sbjct: 1099 ECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHY 1157
Query: 1964 -PASCPSPAPLTTPAVCEGPCVEGC-QC--DAGFVLSADRCVP 2002
P CPS P G +EGC C D F CVP
Sbjct: 1158 QPCLCPS-----QPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP 1195
Score = 305 bits (781), Expect = 8e-82
Identities = 324/1236 (26%), Positives = 472/1236 (38%), Gaps = 187/1236 (15%)
Query: 3272 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 3331
+C WG H+ T D H +DF GTC Y+ +A C F+V + GS +
Sbjct: 44 QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
Query: 3332 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSL--A 3389
+ +++ +T+S + GV ++LP+ + L + +V L L
Sbjct: 96 RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
Query: 3390 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 3444
+ DS + + V Y G +CGLCGN++ ++ + GK A GE C
Sbjct: 154 WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
Query: 3445 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 3502
+ PS + Q + C + P V + C D A G
Sbjct: 214 TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
Query: 3503 HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPF-QCPAHSHYELCGDSCPGSCPSLSAP 3561
C ++ Y C G +R WR P C QCPA+ Y+ CG +C +C +
Sbjct: 266 PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
Query: 3562 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLC 3616
C S+C GC C G VL+ TCVPV QC C LH Y P T C + C
Sbjct: 324 HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---AACQT-C 379
Query: 3617 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTC 3676
RC G V C C H C G TTFD + F GTC
Sbjct: 380 RCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARPYRFHGTC 419
Query: 3677 VYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGV 3736
Y+L Q+ AV ++ G + V V ++ + + VT NG
Sbjct: 420 TYILLQSPQLPEDGALMAVYDKS---GVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
Query: 3737 DMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQLMCGLCGN 3794
LP N + Q + + + T FGL + L ++ VTV + GLCGN
Sbjct: 477 AKWLPYKTRNITV-FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535
Query: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELE 3854
+NGD DDF G G A+ F +SW CP +A +D C
Sbjct: 536 FNGDTTDDFTTSMGIAEGTASLFVDSWR----------AGNCP--AALERETDPCSMSQL 583
Query: 3855 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 3914
K E C +L CH V+P K C++ C +C+ + YV AC
Sbjct: 584 NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
Query: 3915 QAAGGHVEPWRNET-FCPMECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEGCQC 3970
G + WR+ C + C N+ + + C C +LS +C +GC C
Sbjct: 644 SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
Query: 3971 DSGFLYNGQA-CVPIQQCGCYHNGV-YYEPEQTVLIDNCRQQC----------------T 4012
G N + CV QC C G + EQ+ +I+ C +
Sbjct: 704 PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
Query: 4013 CHVGKV--------------------------VVCQEHSCKPGQVCQP---SGGILSCVT 4043
C K V C C+PG VC CV
Sbjct: 764 CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
Query: 4044 KDPC----HGVT----------CRPQETCKEQGGQGVCL--PNYEATCWLWGDPHYHSFD 4087
+ C GV+ CR TC G+ C + +TC L+G+ H +FD
Sbjct: 824 PEECPCEFSGVSYPGGAELHTDCR---TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFD 880
Query: 4088 GRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 4147
G++F F G C Y+LAT C GV+ T F + T+N GN V+ R + + G ++
Sbjct: 881 GQRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIFLGGLSVV 938
Query: 4148 IHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPS 4207
+ V G + + V G +S+ S + + L + ++ + + + +
Sbjct: 939 LAD---RNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRHMTILIRIAR 992
Query: 4208 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 4267
+ +CGLCGN + N +D + +A S SW+ PLC D + P C
Sbjct: 993 ASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGDVSFVTDP-CS 1048
Query: 4268 EDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKAL 4325
+ + C ++S T F TCH+ V +++ CV D C GGD + LC A+
Sbjct: 1049 LNAFRRSWAERKCSVINSQT---FATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAV 1105
Query: 4326 ASYVAACQAAGVVIEDWRAQVGCEITC------PENSHYE---VCGPPC-----PASCPS 4371
A+Y AC GV + DWR C I C ++ H E C P CPS
Sbjct: 1106 AAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPS 1164
Query: 4372 PAPLTTPAVCEGPCVEGC-QC--DAGFVLSADRCVP 4404
P G +EGC C D F CVP
Sbjct: 1165 -----QPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP 1195
Score = 303 bits (775), Expect = 4e-81
Identities = 322/1236 (26%), Positives = 470/1236 (38%), Gaps = 187/1236 (15%)
Query: 2071 ECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2130
+C WG H+ T D H ++F GTC Y+ +A C F+V + GS +
Sbjct: 44 QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
Query: 2131 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSL--A 2188
+ +++ +T+S + GV ++LP+ + L + +V L L
Sbjct: 96 RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
Query: 2189 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 2243
+ DS + + V Y G +CGLCGN++ ++ + GK A GE C
Sbjct: 154 WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
Query: 2244 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 2301
+ PS + Q + C + P V + C D A G
Sbjct: 214 TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
Query: 2302 HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPF-QCPAHSHYELCGDSCPGSCPSLSAP 2360
C ++ Y C G +R WR P C QCPA+ Y+ CG +C +C +
Sbjct: 266 PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
Query: 2361 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLC 2415
C S+C GC C G VL+ TCVPV QC C LH Y P T C + C
Sbjct: 324 HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---AACQT-C 379
Query: 2416 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTC 2475
RC G V C C H C G TTFD R + F GTC
Sbjct: 380 RCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARPYRFHGTC 419
Query: 2476 VYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGV 2535
Y+L Q+ AV ++ G + V V ++ + + VT NG
Sbjct: 420 TYILLQSPQLPEDGALMAVYDKS---GVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
Query: 2536 DMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQLMCGLCGN 2593
LP N + Q + + + T FGL + L ++ VTV + GLCGN
Sbjct: 477 AKWLPYKTRNITV-FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535
Query: 2594 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELE 2653
+NGD DDF G G A+ F +SW CP E ++ C
Sbjct: 536 FNGDTTDDFTTSMGIAEGTASLFVDSWR----------AGNCPAALER--ETDPCSMSQL 583
Query: 2654 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713
K E C +L CH V+P K C++ C +C+ + YV AC
Sbjct: 584 NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
Query: 2714 QAAGGQVEPWRNET-FCPMECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEGCQC 2769
G + WR+ C + C N+ + + C C +LS +C +GC C
Sbjct: 644 SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
Query: 2770 DSGFLYNGQA-CVPIQQCGCYHNG-AYYEPEQTVLIDNCRQQC----------------T 2811
G N + CV QC C G + EQ+ +I+ C +
Sbjct: 704 PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
Query: 2812 CHVGKV--------------------------VVCQEHSCKPGQVCQP---SGGILSCVN 2842
C K V C C+PG VC CV
Sbjct: 764 CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
Query: 2843 KDPC----HGVT----------CRPQETCKEQGGQGVCL--PNYEATCWLWGDPHYHSFD 2886
+ C GV+ CR TC G+ C + +TC L+G+ H +FD
Sbjct: 824 PEECPCEFSGVSYPGGAELHTDCR---TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFD 880
Query: 2887 GRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 2946
G++F F G C Y+LAT C GV+ T F + T+N GN V+ R + + G ++
Sbjct: 881 GQRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIFLGGLSVV 938
Query: 2947 IHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPS 3006
+ V G + + V G +S+ S + + L + ++ + + + +
Sbjct: 939 LAD---RNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRHMTILIRIAR 992
Query: 3007 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 3066
+ +CGLCGN + N +D + +A S SW+ PLC D + P C
Sbjct: 993 ASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGDVSFVTDP-CS 1048
Query: 3067 EDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKAL 3124
+ + C + T F TCH+ V +++ CV D C GGD + LC A+
Sbjct: 1049 LNAFRRSWAERKCSVINSQT---FATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAV 1105
Query: 3125 ASYVAACQAAGVVIEDWRAQVGCEITC------PENSHYE---VCGPPC-----PASCPS 3170
A+Y AC GV + DWR C I C ++ H E C P CPS
Sbjct: 1106 AAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPS 1164
Query: 3171 PAPLTTPAVCEGPCVEGC-QC--DAGFVLSADRCVP 3203
P G +EGC C D F CVP
Sbjct: 1165 -----QPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP 1195
Score = 291 bits (744), Expect = 2e-77
Identities = 310/1240 (25%), Positives = 451/1240 (36%), Gaps = 219/1240 (17%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WG H+ +FD +DF GTCNY+ A T T F+V Q R P S
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPT-----FSV----QLRRGPDGSIS 95
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 1792
R++ LG ++ + I V+ GV++ LP + ++G G S L+ L++
Sbjct: 96 RIIV--ELGASVVTVSEAIISVKDIGVIS-LPYT-SNGLQITPFGQSVRLVAKQLELELE 151
Query: 1793 YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAPGW 1849
W + + V + Y G +CGLCGN D N+ V G L P PG
Sbjct: 152 VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG- 210
Query: 1850 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 1909
+C + P + Q + C L V E F C DV
Sbjct: 211 -EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQADV 258
Query: 1910 CMGG--GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGSPCPAS 1966
G ++ C L+ Y C G + WR+ C + CP N Y+ CGS C +
Sbjct: 259 AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
Query: 1967 CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGSEF 2022
C +P C C GC C G VL+ CVP+ C C +G + G
Sbjct: 319 CSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGEVT 372
Query: 2023 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 2082
A Q CRC G VCT C C G T
Sbjct: 373 IA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFVTT 407
Query: 2083 LDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 2142
D + F GTC Y+L P L + + V ++ S + + +V +
Sbjct: 408 FDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV 464
Query: 2143 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 2202
+S + +G LP++ ++ + + + T+ GL L + V
Sbjct: 465 ISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVG 522
Query: 2203 --YAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPC 2252
+ G GLCGN+N D DD G G W+ G E + PC
Sbjct: 523 PQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----DPC 578
Query: 2253 TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 2312
+ Q C ++ T CH V PA +++ C+ AC + +C A+
Sbjct: 579 SMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGD 638
Query: 2313 YVAACQAAGAQLREWRRP-DFCPFQCPAHSHYELCGDSCPGSCPSLS--APEGCESACR- 2368
YV AC G L WR D C C ++ + +C +C SLS A E SA
Sbjct: 639 YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPV 698
Query: 2369 EGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQ------------------------ 2403
+GC C D ++ CV QC C+ + + L +
Sbjct: 699 DGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQ 758
Query: 2404 ----------TFYP---------GPGCDSLCRCREGGEVSCEPSSCGPHETCR------- 2437
TF G C C+ G V+C P+ C P C
Sbjct: 759 MFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATG-VACVPTKCEPGCVCAEGLYENA 817
Query: 2438 -------------------PSGGSLG------CVAVGSTTCQAS----------GDPHYT 2462
P G L + G CQ G+ H
Sbjct: 818 DGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVI 877
Query: 2463 TFDGRRFDFMGTCVYVLA-QTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521
TFDG+RF F G C Y+LA CG F +L ENV GN V+ +R I + + ++
Sbjct: 878 TFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSV 937
Query: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581
L R + VT ++L V A D+ I + L + ++ + + +
Sbjct: 938 VLADRNYTVTGEEPHVQLGVTPG-----ALSLVVDISIPGRYNLTLIWNRHMTILIRIAR 992
Query: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEG 2641
+CGLCGN+NG+ KDDF+ + A + E NSW+E P C +
Sbjct: 993 ASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---------SPLC---GDV 1040
Query: 2642 CIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNL 2699
++ C ++ E C +++S T ++CH V + C+ D C GG+
Sbjct: 1041 SFVTDPCSLNAFRRSWAERKCSVINSQT--FATCHSKVYHLPYYEACVRDACGCDSGGDC 1098
Query: 2700 SILCSNIHAYVSACQAAGGQVEPWRNETFCPMEC------PQNSHYELCADTCSLGCSAL 2753
LC + AY AC G V+ WR FCP+ C Q+ H E T C+
Sbjct: 1099 ECLCDAVAAYAQACLDKGVCVD-WRTPAFCPIYCGFYNTHTQDGHGEY-QYTQEANCTWH 1156
Query: 2754 SAPLQCP-----------DGCAEGCQCDSGFLYNGQACVP 2782
P CP +GC C D F + CVP
Sbjct: 1157 YQPCLCPSQPQSVPGSNIEGC-YNCSQDEYFDHEEGVCVP 1195
Score = 289 bits (740), Expect = 5e-77
Identities = 311/1240 (25%), Positives = 449/1240 (36%), Gaps = 219/1240 (17%)
Query: 2874 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 2933
C WG H+ +FD +DF GTCNY+ A T T F+V Q R P S
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPT-----FSV----QLRRGPDGSIS 95
Query: 2934 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 2993
R++ LG ++ + I V+ GV++ LP + ++G G S L+ L++
Sbjct: 96 RIIV--ELGASVVTVSEAIISVKDIGVIS-LPYT-SNGLQITPFGQSVRLVAKQLELELE 151
Query: 2994 YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAPGW 3050
W + + V + Y G +CGLCGN D N+ V G L P PG
Sbjct: 152 VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG- 210
Query: 3051 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110
+C + P + Q + C L V E F C DV
Sbjct: 211 -EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQADV 258
Query: 3111 CMGG--GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGPPCPAS 3167
G ++ C L+ Y C G + WR+ C + CP N Y+ CG C +
Sbjct: 259 AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
Query: 3168 CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGSEF 3223
C +P C C GC C G VL+ CVP+ C C +G + G
Sbjct: 319 CSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGEVT 372
Query: 3224 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 3283
A Q CRC G VCT C C G T
Sbjct: 373 IA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFVTT 407
Query: 3284 LDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 3343
D + F GTC Y+L P L + + V ++ S + + +V +
Sbjct: 408 FDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV 464
Query: 3344 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 3403
+S + +G LP++ ++ + + + T+ GL L + V
Sbjct: 465 ISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVG 522
Query: 3404 --YAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPC 3453
+ G GLCGN+N D DD G G W+ G E + PC
Sbjct: 523 PQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----DPC 578
Query: 3454 TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 3513
+ Q C ++ T CH V PA +++ C+ AC + +C A+
Sbjct: 579 SMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGD 638
Query: 3514 YVAACQAAGAQLREWRRP-DFCPFQCPAHSHYELCGDSCPGSCPSLS--APEGCESACR- 3569
YV AC G L WR D C C ++ + +C +C SLS A E SA
Sbjct: 639 YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPV 698
Query: 3570 EGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQ------------------------ 3604
+GC C D ++ CV QC C+ + + L +
Sbjct: 699 DGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQ 758
Query: 3605 ----------TFYP---------GPGCDSLCRCREGGEVSCEPSSCGPHETCR------- 3638
TF G C C+ G V+C P+ C P C
Sbjct: 759 MFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATG-VACVPTKCEPGCVCAEGLYENA 817
Query: 3639 -------------------PSGGSLG------CVAVGSTTCQAS----------GDPHYT 3663
P G L + G CQ G+ H
Sbjct: 818 DGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVI 877
Query: 3664 TFDGHRFDFMGTCVYVLA-QTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722
TFDG RF F G C Y+LA CG F +L ENV GN V+ +R I + + ++
Sbjct: 878 TFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSV 937
Query: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
L R + VT ++L V A D+ I + L + ++ + + +
Sbjct: 938 VLADRNYTVTGEEPHVQLGVTPG-----ALSLVVDISIPGRYNLTLIWNRHMTILIRIAR 992
Query: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAG 3842
+CGLCGN+NG+ KDDF+ + A + E NSW+E P C S
Sbjct: 993 ASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---------SPLCGDVS-- 1041
Query: 3843 CIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNL 3900
+D C ++ E C +++S T ++CH V + C+ D C GG+
Sbjct: 1042 -FVTDPCSLNAFRRSWAERKCSVINSQT--FATCHSKVYHLPYYEACVRDACGCDSGGDC 1098
Query: 3901 SILCSNIHAYVSACQAAGGHVEPWRNETFCPMEC------PQNSHYELCADTCSLGCSAL 3954
LC + AY AC G V+ WR FCP+ C Q+ H E T C+
Sbjct: 1099 ECLCDAVAAYAQACLDKGVCVD-WRTPAFCPIYCGFYNTHTQDGHGEY-QYTQEANCTWH 1156
Query: 3955 SAPLQCP-----------DGCAEGCQCDSGFLYNGQACVP 3983
P CP +GC C D F + CVP
Sbjct: 1157 YQPCLCPSQPQSVPGSNIEGC-YNCSQDEYFDHEEGVCVP 1195
Score = 283 bits (724), Expect = 3e-75
Identities = 311/1235 (25%), Positives = 445/1235 (36%), Gaps = 223/1235 (18%)
Query: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134
C WG H+ +FD +DF GTCNY+ A T T F+V Q R P S
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPT-----FSV----QLRRGPDGSIS 95
Query: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 4194
R++ LG ++ + I V+ GV++ LP + ++G G S L+ L++
Sbjct: 96 RIIV--ELGASVVTVSEAIISVKDIGVIS-LPYT-SNGLQITPFGQSVRLVAKQLELELE 151
Query: 4195 YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAPGW 4251
W + + V + Y G +CGLCGN D N+ V G L P PG
Sbjct: 152 VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG- 210
Query: 4252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311
+C + P + Q + C L + V E F C DV
Sbjct: 211 -EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQADV 258
Query: 4312 CMGG--GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGPPCPAS 4368
G ++ C L+ Y C G + WR+ C + CP N Y+ CG C +
Sbjct: 259 AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
Query: 4369 CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGSEF 4424
C +P C C GC C G VL+ CVP+ C C +G + G
Sbjct: 319 CSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGEVT 372
Query: 4425 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 4484
A Q CRC G VCT C C G T
Sbjct: 373 IA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFVTT 407
Query: 4485 LDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 4544
D + F GTC Y+L P L + + V ++ S + + +V +
Sbjct: 408 FDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV 464
Query: 4545 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 4604
+S + +G LP++ ++ + + + T+ GL L + V
Sbjct: 465 ISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVG 522
Query: 4605 --YAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPC 4654
+ GLCGN+N D DD G G W+ G E + PC
Sbjct: 523 PQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----DPC 578
Query: 4655 TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 4714
+ Q C ++ T CH V PA +++ C+ AC + +C A+
Sbjct: 579 SMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGD 638
Query: 4715 YVAACQAAGAQLGEWRRP-DFCPLQCPAHSHYELCGDSCPVSCPSLS--APEGCESACR- 4770
YV AC G L WR D C + C ++ + +C +C SLS A E SA
Sbjct: 639 YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPV 698
Query: 4771 EGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPL----------------GEVFYP---- 4809
+GC C D ++ CV QC C+ +G + L G + P
Sbjct: 699 DGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQ 758
Query: 4810 -----------------------GPECERRCE------------CGPGGHVTCQEG---- 4830
G C C+ C PG C EG
Sbjct: 759 MFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPG--CVCAEGLYEN 816
Query: 4831 --AACGPHEECRLE-DGVQ---------ACHATGCGR--------------CLANGGIHY 4864
C P EEC E GV C C R C G H
Sbjct: 817 ADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHV 876
Query: 4865 ITLDGRVYDLHGSCSYVLA-QVCHPKPGDEDFSIVLEK----NAAGDLQRLLVTVAGQVV 4919
IT DG+ + G+C Y+LA VC F I+ E N+ R + G +
Sbjct: 877 ITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLS 936
Query: 4920 SLAQGQQVTVDGEA--VALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSP 4977
+ + TV GE V L V G + + + + + L L+++ +L+ I
Sbjct: 937 VVLADRNYTVTGEEPHVQLGVTPGALSLVVD---ISIPGRYNLTLIWNRHMTILIRIARA 993
Query: 4978 FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCL 5037
+ LCGLCGNFNGN DDF + ASS +W+ S CG+ C
Sbjct: 994 SQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK---ESPLCGDVSFV--TDPCS 1048
Query: 5038 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLA 5095
+ C + + FATC + + Y+ CV D C GD LC ++A
Sbjct: 1049 LNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVA 1106
Query: 5096 AYTAACQAAGVAVKPWRTDSFCPLHCPAHS--------------------HYSICTRTCQ 5135
AY AC GV V WRT +FCP++C ++ HY C Q
Sbjct: 1107 AYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQ 1165
Query: 5136 GSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 5170
S + GC C D+ F +GVC+P
Sbjct: 1166 PQSVPGSNIEGC-----YNCSQDEYFDHEEGVCVP 1195
Score = 270 bits (690), Expect = 3e-71
Identities = 318/1266 (25%), Positives = 464/1266 (36%), Gaps = 246/1266 (19%)
Query: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 2512
C G H++TFD +DF GTC Y+ A TC + F+V G S++R+I
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQLRRGPDG----SISRII 98
Query: 2513 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVI---ETDFGLRVAY 2569
V++ + + + V GV + LP +NG ++ + G V + + + L V +
Sbjct: 99 -VELGASVVTVSEAIISVKDIGV-ISLPYT-SNG-LQITPFGQSVRLVAKQLELELEVVW 154
Query: 2570 DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 2629
++ V V Y MCGLCGN++G ++F G ++F + P C
Sbjct: 155 GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
Query: 2630 LPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 2689
++ P ++ Q C L + P S K + + C
Sbjct: 214 T--------------FQDIPSTHVRQAQHARICTQLLTLVAPECSVSK----EPFVLSCQ 255
Query: 2690 FDLCLGG--GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPM-ECPQNSHYELCADTC 2746
D+ G + C+ + Y C G V WR+ C + +CP N Y+ C C
Sbjct: 256 ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC 315
Query: 2747 SLGCSALSAPLQCPDGCAEGCQCDSGF----LYNGQACVPIQQCGCYHNGAYYEPEQTVL 2802
CS + C C GC C G L N CVP+ QC C +GA Y P + V
Sbjct: 316 VKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGE-VT 372
Query: 2803 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGG 2862
I C Q C C +G+ V C E PC G C +GG
Sbjct: 373 IAAC-QTCRCTLGRWV-CTER---------------------PCPG-------HCSLEGG 402
Query: 2863 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 2922
V +FD R + F GTC Y+L + P + G
Sbjct: 403 SFVT-----------------TFDARPYRFHGTCTYILLQS--PQLPEDGA--LMAVYDK 441
Query: 2923 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 2982
+ S V VV ++ I I +DE+ V NG LP + I+V + S
Sbjct: 442 SGVSHSETSLVAVVYLSRQD-KIVISQDEV--VTNNGEAKWLPYKTRN--ITVFRQTSTH 496
Query: 2983 LLVA-DFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 3039
L +A FGL++ ++ VT+ + G GLCGN + + +D G +
Sbjct: 497 LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
Query: 3040 IWGGSWRAPGWDPLCWDECRGSCPT--------CPEDRLEQYEGPGFCGPLAPGTGGPFT 3091
++ SWRA G+CP C +L + C L TG F
Sbjct: 557 LFVDSWRA------------GNCPAALERETDPCSMSQLNKVCAETHCSMLLR-TGTVFE 603
Query: 3092 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEIT 3150
CHA V P F+K CV C +C AL YV AC GV++ WR+ V C I
Sbjct: 604 RCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIP 663
Query: 3151 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS------------- 3197
C N+ + C +C S + T V+GC C G L+
Sbjct: 664 CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC 723
Query: 3198 ---------ADRCVPLN-------NG------------CGCWANGTYHEA--GSEFWADG 3227
A++ +N NG C A T+ SE
Sbjct: 724 ILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGA 783
Query: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVC--GLLPSGQHGCQPVSTAECQ----------- 3274
C+ C+ G + C P C G VC GL + C P C+
Sbjct: 784 ACAPTCQMLATG--VACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAE 841
Query: 3275 ----------------------------AWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGP 3306
+G+ H +T DG RF F G CEY+L+ G
Sbjct: 842 LHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGV 901
Query: 3307 PLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLD 3366
F + N G+ V+ +R++ + + S+ L+ R V G + QL
Sbjct: 902 NDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLA---DRNYTVTGEEPHV--QLG 956
Query: 3367 SLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAV 3426
A D+ + L+L ++ + +R+ A LCGLCGN+N + DD +
Sbjct: 957 VTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETR 1016
Query: 3427 GGKPAGWQVGGAQG------CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPC 3480
A ++ CG+ PC+ C VI++ A C
Sbjct: 1017 SRYVASSELELVNSWKESPLCGDV--SFVTDPCSLNAFRRSWAERKCSVINSQ--TFATC 1072
Query: 3481 HGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQC 3538
H V Y++ C+ DAC G LC AVA Y AC G + +WR P FCP C
Sbjct: 1073 HSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYC 1131
Query: 3539 --------PAHSHYELCGD-SC-----PGSCPSLSAPEGCESACREGCV-C--DAGFVLS 3581
H Y+ + +C P CP S P+ + EGC C D F
Sbjct: 1132 GFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP--SQPQSVPGSNIEGCYNCSQDEYFDHE 1189
Query: 3582 GDTCVP 3587
CVP
Sbjct: 1190 EGVCVP 1195
Score = 270 bits (689), Expect = 4e-71
Identities = 317/1267 (25%), Positives = 462/1267 (36%), Gaps = 248/1267 (19%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713
C G H++TFD H +DF GTC Y+ A TC + F+V G S++R+I
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQLRRGPDG----SISRII 98
Query: 3714 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVI---ETDFGLRVAY 3770
V++ + + + V GV + LP +NG ++ + G V + + + L V +
Sbjct: 99 -VELGASVVTVSEAIISVKDIGV-ISLPYT-SNG-LQITPFGQSVRLVAKQLELELEVVW 154
Query: 3771 DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 3830
++ V V Y MCGLCGN++G ++F G + + P
Sbjct: 155 GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-------------KFLEPHKFA 201
Query: 3831 LPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 3890
PG C D P ++ Q C L + P S K + + C
Sbjct: 202 ALQKLDDPGEI-CTFQD-IPSTHVRQAQHARICTQLLTLVAPECSVSK----EPFVLSCQ 255
Query: 3891 FDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPM-ECPQNSHYELCADTC 3947
D+ G + C+ + Y C G V WR+ C + +CP N Y+ C C
Sbjct: 256 ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC 315
Query: 3948 SLGCSALSAPLQCPDGCAEGCQCDSGF----LYNGQACVPIQQCGCYHNGVYYEPEQTVL 4003
CS + C C GC C G L N CVP+ QC C +G Y P +
Sbjct: 316 VKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT- 372
Query: 4004 IDNCRQQCTCHVGKVVVCQEHSCKPGQ-VCQPSGGILSCVTKDPCHGVTCRPQETCKEQG 4062
+ CQ C G+ VC T+ PC G C +G
Sbjct: 373 --------------IAACQTCRCTLGRWVC----------TERPCPG-------HCSLEG 401
Query: 4063 GQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTK 4122
G V +FD R + F GTC Y+L + P + G
Sbjct: 402 GSFVT-----------------TFDARPYRFHGTCTYILLQS--PQLPEDGA--LMAVYD 440
Query: 4123 NQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASK 4182
+ S V VV ++ I I +DE+ V NG LP + I+V + S
Sbjct: 441 KSGVSHSETSLVAVVYLSRQD-KIVISQDEV--VTNNGEAKWLPYKTRN--ITVFRQTST 495
Query: 4183 ALLVA-DFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSI 4239
L +A FGL++ ++ VT+ + G GLCGN + + +D G +
Sbjct: 496 HLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA 555
Query: 4240 PIWGGSWRAPGWDPLCWDECRGSCPT--------CPEDRLEQYEGPGFCGPLSSGTGGPF 4291
++ SWRA G+CP C +L + C L TG F
Sbjct: 556 SLFVDSWRA------------GNCPAALERETDPCSMSQLNKVCAETHCSMLLR-TGTVF 602
Query: 4292 TTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEI 4350
CHA V P F+K CV C +C AL YV AC GV++ WR+ V C I
Sbjct: 603 ERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTI 662
Query: 4351 TCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS------------ 4398
C N+ + C +C S + T V+GC C G L+
Sbjct: 663 PCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCP 722
Query: 4399 ----------ADRCVPLN-------NG------------CGCWANGTYHEA--GSEFWAD 4427
A++ +N NG C A T+ SE
Sbjct: 723 CILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFG 782
Query: 4428 GTCSQWCRCGPGGGSLVCTPASCGLGEVC--GLLPSGQHGCQPVSTAECQ---------- 4475
C+ C+ G + C P C G VC GL + C P C+
Sbjct: 783 AACAPTCQMLATG--VACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
Query: 4476 -----------------------------AWGDPHYVTLDGHRFDFQGTCEYLLSAPCHG 4506
+G+ H +T DG RF F G CEY+L+ G
Sbjct: 841 ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
Query: 4507 PPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQL 4566
F + N G+ V+ +R++ + + S+ L+ R V G + QL
Sbjct: 901 VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLA---DRNYTVTGEEPHV--QL 955
Query: 4567 DSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKA 4626
A D+ + L+L ++ + +R+ A LCGLCGN+N + DD +
Sbjct: 956 GVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFET 1015
Query: 4627 VGGKPAGWQVGGAQG------CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAP 4680
A ++ CG+ PC+ C VI++ A
Sbjct: 1016 RSRYVASSELELVNSWKESPLCGDV--SFVTDPCSLNAFRRSWAERKCSVINSQ--TFAT 1071
Query: 4681 CHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQ 4738
CH V Y++ C+ DAC G LC AVA Y AC G + +WR P FCP+
Sbjct: 1072 CHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIY 1130
Query: 4739 C--------PAHSHYELCGD-SC-----PVSCPSLSAPEGCESACREGCV-C--DAGFVL 4781
C H Y+ + +C P CP S P+ + EGC C D F
Sbjct: 1131 CGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP--SQPQSVPGSNIEGCYNCSQDEYFDH 1188
Query: 4782 SGDTCVP 4788
CVP
Sbjct: 1189 EEGVCVP 1195
Score = 263 bits (672), Expect = 3e-69
Identities = 258/1054 (24%), Positives = 404/1054 (38%), Gaps = 195/1054 (18%)
Query: 4473 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 4532
+C WG H+ T D H +DF GTC Y+ +A C F+V + GS +
Sbjct: 44 QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
Query: 4533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSL--A 4590
+ +++ +T+S + GV ++LP+ + L + +V L L
Sbjct: 96 RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
Query: 4591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 4645
+ DS + + V Y +CGLCGN++ ++ + GK A GE C
Sbjct: 154 WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
Query: 4646 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 4703
+ PS + Q + C + P V + C D A G
Sbjct: 214 TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
Query: 4704 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAP 4762
C ++ Y C G + WR P C + QCPA+ Y+ CG +C +C +
Sbjct: 266 PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
Query: 4763 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818
C S+C GC C G VL+ TCVPV QC C+ G Y GEV
Sbjct: 324 HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---------- 373
Query: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 4877
AAC + CR G C C G C GG T D R Y HG+
Sbjct: 374 ------------AAC---QTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGT 418
Query: 4878 CSYVLAQVCHPK-PGDEDFSIVLEKNAAGDLQRLLVTVA----GQVVSLAQGQQVTVDGE 4932
C+Y+L Q P+ P D V +K+ + LV V + ++Q + VT +GE
Sbjct: 419 CTYILLQ--SPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
Query: 4933 AVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDA--HLLMSIPSPFRGRLCGLCGNF 4989
A LP + V + ++ + T+ GL L+ +++ FRG+ GLCGNF
Sbjct: 477 AKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNF 536
Query: 4990 NGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEA 5049
NG+ +DDF G A + F +WRA CP L ET P ++
Sbjct: 537 NGDTTDDFTTSMGIAEGTASLFVDSWRAGN-------------CPAALERETDPCSMSQL 583
Query: 5050 --------CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAAC 5101
C L F C A ++P+ ++++CVY C + +C +L Y AC
Sbjct: 584 NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
Query: 5102 QAAGVAVKPWRTD-SFCPLHCPAHSHYSICTRTCQGSCAALSG-LTGC--TTRCFEGCEC 5157
GV + WR+ C + C ++ +S ++ C+ +C +LS T C + +GC C
Sbjct: 644 SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
Query: 5158 DDRFLLSQ-GVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERC----------------- 5198
D L+Q G C+ C C G +++ S + + + C
Sbjct: 704 PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
Query: 5199 --------SCSSSS-----------------GLTCQAAGCPPGRVC-------------- 5219
SCS SS G+ C C PG VC
Sbjct: 764 CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
Query: 5220 -----------------EVKAEARNCWATRG------------LCVLSVGANLTTFDGAR 5250
E+ + R C +RG C L ++ TFDG R
Sbjct: 824 PEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQR 883
Query: 5251 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKG 5310
Y L++ G+ ++ P ++++ E IC + F G+ + ++
Sbjct: 884 FVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRN 943
Query: 5311 VWVNGLRVDLPAEKLASV--SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKL 5368
V G + P +L ++S D S+ R + +W + + + ++ L
Sbjct: 944 YTVTG---EEPHVQLGVTPGALSLVVDISIPGRYNLTL-IW-NRHMTILIRIARASQDPL 998
Query: 5369 CGACGNFDGDQTNDWHD------SQEKPAMEKWR 5396
CG CGNF+G+ +D+ S E + W+
Sbjct: 999 CGLCGNFNGNMKDDFETRSRYVASSELELVNSWK 1032
Score = 250 bits (639), Expect = 2e-65
Identities = 217/779 (27%), Positives = 330/779 (42%), Gaps = 96/779 (12%)
Query: 472 CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS--RRVSYVG 529
C G H++TFD YD GTC+Y C D P FSV+ + GS R + +G
Sbjct: 45 CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCK--DAFPTFSVQLRRGPDGSISRIIVELG 102
Query: 530 LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY 589
V +S+ ++G + + + L ++ +R+ +E+V+G
Sbjct: 103 ASVVTVSEAIISVK--DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP---- 156
Query: 590 DWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLC 649
D L + + ++ Q+CGLCGN++G ++F++ +G + +FA+ KLDD +C
Sbjct: 157 --DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
Query: 650 EDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV-- 707
+ P+ QAQH R+C L L P ++ PF+ C D+
Sbjct: 214 ---TFQDIPSTHVRQAQH---ARICTQLLTLVAP----ECSVSKEPFVLSCQADVAAAPQ 263
Query: 708 GGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL-SCPANSRYELCGPACPTSCNGAA 766
G + S C LS Y++ C +G V WRSP C + CPAN Y+ CG AC +C+
Sbjct: 264 PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN-- 321
Query: 767 APSNCSGRPCVEGCVCLPGFV----ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 822
P + C GC C G V ++ CVP + C C G APG+ A CQ
Sbjct: 322 -PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIA--ACQ- 377
Query: 823 RCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF 882
TC + C ++ CP G C G +FD R + F
Sbjct: 378 --TCRCTLGRWVCTER-PCP-------------------GHCSLEGGSFVTTFDARPYRF 415
Query: 883 MGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVE--ARGVKVAVRREYPG 940
GTCTY+L+ Q+ LP L+ + + S T V V +R K+ + ++
Sbjct: 416 HGTCTYILL----QSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQD--E 469
Query: 941 QVLVDDVLQYLPFQAADGQVQVFRQ-GRDAVVRTDFGLTVTYD----WNARVTAKVPSSY 995
V + ++LP++ + + VFRQ + T FGL + + A VT V +
Sbjct: 470 VVTNNGEAKWLPYKTRN--ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVT--VGPQF 525
Query: 996 AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC--GATEPGDCPKLDS 1053
GLCGNFNGD DD G A F +SW+ P T+P +L+
Sbjct: 526 RGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNK 585
Query: 1054 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1113
+ A+ C +L F CH+ ++P + CVY C +C AL Y
Sbjct: 586 VCAE-----THCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYV 640
Query: 1114 AACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECH----- 1167
AC G + WRS + C + C ++ + S C +C L +ECH
Sbjct: 641 HACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSL---SDRATECHHSAVP 697
Query: 1168 -EGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
+GC C +G L+ + C+ A C C+ +G + G CHC G L SC
Sbjct: 698 VDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGI--TCHCINGRL-SC 753
Score = 169 bits (429), Expect = 5e-41
Identities = 157/578 (27%), Positives = 247/578 (42%), Gaps = 64/578 (11%)
Query: 4840 RLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL 4899
RL+D Q A G+C G H+ T D VYD G+C+Y+ A C K FS+ L
Sbjct: 31 RLKDSPQT--APDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQL 86
Query: 4900 EKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL---QT 4956
+ G + R++V + VV++++ D ++LP +++T G+++ L Q
Sbjct: 87 RRGPDGSISRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQL 146
Query: 4957 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 5016
L +++ D+HL++ + + G++CGLCGNF+G +++FV G F A +
Sbjct: 147 ELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-HKFAALQK 205
Query: 5017 APGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQC 5076
GE C Q P + + C QL P + +S + C
Sbjct: 206 LDDP----GEICTFQDIP---STHVRQAQHARICTQLLTLVAP----ECSVSKEPFVLSC 254
Query: 5077 VYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL-HCPAHSHYSICTRT 5133
D+ A Q G + C +L+ Y+ C G V+ WR+ C + CPA+ Y C
Sbjct: 255 QADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSA 314
Query: 5134 CQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDCGCT-HNGRYLPVNSS 5188
C +C+ + C++ C GC C + +L + C+PV C C H Y P +
Sbjct: 315 CVKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT 372
Query: 5189 LLTSDCSERCSCSSSSGLTCQAAGCPPGR-VCEVKAEARNCWATRGLCVLSVGANLTTFD 5247
+ CQ C GR VC R C G C L G+ +TTFD
Sbjct: 373 I----------------AACQTCRCTLGRWVC----TERPC---PGHCSLEGGSFVTTFD 409
Query: 5248 GARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTP 5307
Y L + P L V + + H +T V V++ QD +V ++
Sbjct: 410 ARPYRFHGTCTYIL-LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV-ISQ 467
Query: 5308 NKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHA 5365
++ V NG LP K +++V R L + G++ V L + V V
Sbjct: 468 DEVVTNNGEAKWLP-YKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFR 526
Query: 5366 GKLCGACGNFDGDQTNDWHDSQ---EKPA---MEKWRA 5397
G+ G CGNF+GD T+D+ S E A ++ WRA
Sbjct: 527 GQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA 564
Score = 168 bits (426), Expect = 1e-40
Identities = 146/500 (29%), Positives = 210/500 (42%), Gaps = 82/500 (16%)
Query: 744 SCPANSRYELC--------GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG-GACV 794
SC A ++ C G AC +C A C C GCVC G + G CV
Sbjct: 763 SCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCV 822
Query: 795 PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 854
P C C F G+ G E+ D C R C+C+ R + +C G C
Sbjct: 823 PPEECPCEFSGVSYPGGAELHTD--C-RTCSCS--------RGRWACQQGTHCP------ 865
Query: 855 GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRG 913
TC G+ H ++FDG+RF F G C Y+L CG N + P F++L EN G
Sbjct: 866 -------STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG 918
Query: 914 SQTVSYTRAVRVEARGVKVAVR-REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 972
+ V+ +RA+++ G+ V + R Y V ++ G + + D +
Sbjct: 919 NSGVTCSRAIKIFLGGLSVVLADRNYT----VTGEEPHVQLGVTPGALSLVV---DISIP 971
Query: 973 TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW 1032
+ LT+ ++ + + ++ + + LCGLCGNFNG+ DD R A++ L NSW
Sbjct: 972 GRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSW 1031
Query: 1033 QEETRPGCG----ATEPGDCPKLDSLVA-QQLQSKNECGILADPKGPFRECHSKLDPQGA 1087
+E P CG T+P C SL A ++ ++ +C ++ F CHSK+
Sbjct: 1032 KES--PLCGDVSFVTDP--C----SLNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPY 1081
Query: 1088 VRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
CV D C G LCDA+A YA AC G V WR+ CP+ C ++ +
Sbjct: 1082 YEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQD 1140
Query: 1146 SYG---------C-----PLSCGDLP--VPGGCGSECHEGCVCDEGFALSGESCLPLASC 1189
+G C P C P VPG C+ C DE F C+P
Sbjct: 1141 GHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCY-NCSQDEYFDHEEGVCVP---- 1195
Query: 1190 GCVHQGTYHPPGQTFYPGPG 1209
C+ T PP P G
Sbjct: 1196 -CMPPTTPQPPTTPQLPTTG 1214
Score = 135 bits (340), Expect = 1e-30
Identities = 119/435 (27%), Positives = 177/435 (40%), Gaps = 45/435 (10%)
Query: 450 AAGQRCQVVGGKAGCVAEST-AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL--CSEDD 506
AA Q C+ G+ C C +G TTFD R Y GTC+Y +++ ED
Sbjct: 374 AACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDG 433
Query: 507 TLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566
L A ++ H + V+ V L + + +++ EV V N +
Sbjct: 434 ALMAVYDKSGVSHSETSLVAVVYL----SRQDKIVISQDEV----VTNNGEAKWLPYKTR 485
Query: 567 RLRVY-QSGPRAVVELVFGL--VVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
+ V+ Q+ + FGL VV Q +++ +F+ Q GLCGN+NGD DDF
Sbjct: 486 NITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFT 545
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
T G A F SW+ + C + C+ Q + C ML +
Sbjct: 546 TSMGIAEGTASLFVDSWRAGN----CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTV 601
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA-NCP 742
F CH T++P PF ++CVY C +C L Y AC G+ + WRS NC
Sbjct: 602 FERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCT 661
Query: 743 LSCPANSRYELCGPACPTSC---NGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASS 798
+ C N+ + AC +C + A + S P V+GC C G ++ G CV +
Sbjct: 662 IPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP-VDGCNCPDGTYLNQKGECVRKAQ 720
Query: 799 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTC---RDKQSCPAGERCSVQNGLLG 855
C C +G + L ++ NG +TC + SCP Q L
Sbjct: 721 CPCILEGYKFI---------LAEQSTVING----ITCHCINGRLSCPQ----RPQMFLAS 763
Query: 856 CY-PDRFGTCQGSGD 869
C P F +C S +
Sbjct: 764 CQAPKTFKSCSQSSE 778
Score = 127 bits (320), Expect = 2e-28
Identities = 108/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)
Query: 444 CEGMQCAAGQ-RCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMV-EL 501
C C+ G+ CQ G ST C G+ H TFDG+R+ G C Y + ++
Sbjct: 846 CRTCSCSRGRWACQ-----QGTHCPST--CTLYGEGHVITFDGQRFVFDGNCEYILATDV 898
Query: 502 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDN------Q 555
C +D+ P F + +N G+ V+ S ++ + G + VL D +
Sbjct: 899 CGVNDSQPTFKILTENVICGNSGVTC---------SRAIKIFLGGLSVVLADRNYTVTGE 949
Query: 556 RSRLPVSLSEGRLRVYQSGPRAVVELV----FGLVVTYDWDCQLALSLPARFQDQVCGLC 611
+ + ++ G L + VV++ + L + ++ + + + QD +CGLC
Sbjct: 950 EPHVQLGVTPGALSL-------VVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLC 1002
Query: 612 GNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGD 671
GN+NG+ DDF T +A +E +SWK LC D P C+ + +
Sbjct: 1003 GNFNGNMKDDFETRSRYVASSELELVNSWKESP---LCGDVSFVTDP-CSLNAFRRSWAE 1058
Query: 672 RLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV--GGERLSLCRGLSAYAQACLELG 729
R C ++ FA CH + P+ E CV D C GG+ LC ++AYAQACL+ G
Sbjct: 1059 RKCSVIN--SQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKG 1116
Query: 730 ISVGDWRSPANCPLSC--------PANSRYELCGPACPTSCNGAAAPSNCSGRP------ 775
+ V DWR+PA CP+ C + Y+ A +C P C +P
Sbjct: 1117 VCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEA---NCTWHYQPCLCPSQPQSVPGS 1172
Query: 776 CVEGCV-CLPG--FVASGGACVP 795
+EGC C F G CVP
Sbjct: 1173 NIEGCYNCSQDEYFDHEEGVCVP 1195
>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2852
Score = 308 bits (790), Expect = 7e-83
Identities = 310/1217 (25%), Positives = 448/1217 (36%), Gaps = 192/1217 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 821
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 1762 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 1818
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 1875
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 1876 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 1933
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 1934 GVVIEDWRAQVGCEITC 1950
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 306 bits (785), Expect = 3e-82
Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%)
Query: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643
CV +C C YP G S C TC + G
Sbjct: 394 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
Query: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702
C AV C +GD H+TTFDG R+ F TC Y+LA++ + F V +N
Sbjct: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871
FGNSW+ + SP + GS P D C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
Query: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031
CVP QC C+ GV Y P + + C C G V+ C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
Query: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 4336 GVVIEDWRAQVGCEITC 4352
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 304 bits (778), Expect = 2e-81
Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%)
Query: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442
CV +C C YP G S C TC + G
Sbjct: 394 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
Query: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501
C AV C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670
FGNSW+ + SP + GS P + C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
Query: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830
CVP QC C+ G Y P + + C C G V+ C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
Query: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 3135 GVVIEDWRAQVGCEITC 3151
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 298 bits (762), Expect = 1e-79
Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%)
Query: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303
AP P S P P L+Q G G + PF CHA+V P F
Sbjct: 243 EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 297
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361
C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
CPASC P + E CV+GC C G + CV C C +GT + G
Sbjct: 358 IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 413
Query: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481
S D C+ C C G C+ A C AEC GD H
Sbjct: 414 SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 448
Query: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539
+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ ++
Sbjct: 449 FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
Query: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596
+TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 504 DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 562
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648
+ L+V + GLCG +N + DD + G P W+ A C VS
Sbjct: 563 LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 620
Query: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708
PC Q + AC V+ T APC + P YF+ C DAC+ G P L
Sbjct: 621 SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 676
Query: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765
C +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 677 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
Query: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810
C EGC C D D CVP QC C G YP G+ P
Sbjct: 737 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 796
Query: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829
C+ R P G V TC++
Sbjct: 797 DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 856
Query: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859
G AC EEC + + CH C R C A
Sbjct: 857 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 916
Query: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916
G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 917 GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 965
Query: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1025
Query: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1081
Query: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q GD
Sbjct: 1082 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
C S++AY C GVAV WRT CP C
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 280 bits (716), Expect = 3e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 254 bits (649), Expect = 2e-66
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 248 bits (634), Expect = 9e-65
Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%)
Query: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882
C PS + SC N C H C C+ G P ++ C WG H
Sbjct: 33 CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 87
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941
+FDG + G +Y L P + F++ N + G+ + R V++ +
Sbjct: 88 ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 142
Query: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001
G IH + +V G+ LP + R+ Q A ++ +++D V
Sbjct: 143 GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 197
Query: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053
+ + G GLCGN + +P +D V +G L + + SW+ AP P L
Sbjct: 198 IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 257
Query: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113
C P + EQ E L P PF CHA+V P F C D+C
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 308
Query: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171
GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C CPASC
Sbjct: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 365
Query: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231
P + E CV+GC C G + CV C C +GT + GS D C+
Sbjct: 366 HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 422
Query: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291
C C G C+ A C AEC GD H+ T DG R+ F
Sbjct: 423 -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 459
Query: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347
TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ +TL+
Sbjct: 460 PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
Query: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406
L D + P+ D+ LS + V T G+ + +D + + L+V +
Sbjct: 515 GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458
GLCG +N + DD + G P W+ A C VS PC Q
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 631
Query: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518
+ AC V+ T APC + P YF+ C DAC+ G P LC +A Y C
Sbjct: 632 AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 687
Query: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569
+ G + R C C A Y C C +C L++PE C C
Sbjct: 688 RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747
Query: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627
EGC C D D CVP QC C YP G + P G C C++ G +SC+
Sbjct: 748 EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 803
Query: 3628 PSSCGPHETCRPSG 3641
S P C P+G
Sbjct: 804 --SRAPAAAC-PAG 814
Score = 248 bits (634), Expect = 9e-65
Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897
AP P L C P + EQ E L P PF CHA+V
Sbjct: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
Query: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 294 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
Query: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015
Y C + CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 354 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
Query: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075
+ GS D C+ C C G C+ A C AEC
Sbjct: 410 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 445 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
Query: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 500 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
Query: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
P LC +A Y C+ G + R C C A Y C C +C L++PE
Sbjct: 674 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
Query: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
C C EGC C D D CVP QC C YP G + P G
Sbjct: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 791
Query: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440
C C++ G +SC+ S P C P+G
Sbjct: 792 --HCHCKD-GVMSCD--SRAPAAAC-PAG 814
Score = 161 bits (408), Expect = 1e-38
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 115 bits (287), Expect = 2e-24
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1136 C 1136
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 1e-19
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 92.4 bits (228), Expect = 1e-17
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 5195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 5196 ERCSCSSSSGLTCQAAGCPPGR 5217
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 91.3 bits (225), Expect = 2e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 90.1 bits (222), Expect = 5e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2226
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2227 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2270
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2271 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2322
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2383 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2441 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 86.3 bits (212), Expect = 8e-16
Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 848 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
Query: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
S CT C + C A+GD HY T DG FDF G C+ L
Sbjct: 901 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
Query: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
+F+V V N + S + + +++ + N + D +
Sbjct: 941 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
Query: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469
++++ P ++ Q G + CP P +E F + +
Sbjct: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
Query: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
Query: 3528 WRRPDFCPFQC 3538
WR P CP+ C
Sbjct: 1160 WRTPRLCPYDC 1170
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392
EGCVC G +L C+P +C C
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593
EGCVC G +L C+P +C C
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 84.7 bits (208), Expect = 2e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 84.3 bits (207), Expect = 3e-15
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 848 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
Query: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099
S CT C + C A+GD HY T DG F+F G C+ L
Sbjct: 901 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
Query: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159
+F+V V N + S + + +++ + N + D +
Sbjct: 941 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
Query: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268
++++ P ++ Q G + CP P +E F + +
Sbjct: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
Query: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
Query: 2327 WRRPDFCPFQC 2337
WR P CP+ C
Sbjct: 1160 WRTPRLCPYDC 1170
Score = 83.6 bits (205), Expect = 5e-15
Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%)
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613
S P+LS EG A + + TCVP+ + C+
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
Query: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662
C EG + S P P G LG C + C+ S D +
Sbjct: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
Query: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
Query: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
Query: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838
GLCG +GD +D +GS G A + F +SW+ VP S T P
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
Query: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
S C +D C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2225 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2266
Query: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958
+ C + YV+ C +E WR +CP C +S Y+ C C P
Sbjct: 2267 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2317
Query: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999
C DG EGC C G + + C+P +C C + GV E
Sbjct: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
Query: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046
+ L C+ Q C +V + C +P + L TKDP
Sbjct: 2378 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
Query: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075
C G+ TCRP + C P+Y C
Sbjct: 2436 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 82.0 bits (201), Expect = 1e-14
Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%)
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412
S P+LS EG A + + TCVP+ + C+
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
Query: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461
C EG + S P P G LG C + C+ S D +
Sbjct: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
Query: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
Query: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
Query: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632
GLCG +GD +D +GS G A + F +SW+ VP S P
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
Query: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692
+C + +C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2225 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2264
Query: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752
+ C + YV+ C +E WR +CP C +S Y+ C C
Sbjct: 2265 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2313
Query: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793
P C DG EGC C G + + C+P +C C + A
Sbjct: 2314 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372
Query: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845
E + L C+ Q C +V + C +P + L KDP
Sbjct: 2373 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2430
Query: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874
C G+ TCRP + C P+Y C
Sbjct: 2431 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 78.6 bits (192), Expect = 2e-13
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 67.0 bits (162), Expect = 5e-10
Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%)
Query: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856
T + Q C H+ G+++ + P P GIL G+ R
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2024
Query: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
G C P +E C ++ D + +FDG Y+L+ + + LT
Sbjct: 2025 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2074
Query: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971
+ K+ N G+ P V ++ + L ++I + KV V+ PVS
Sbjct: 2075 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2132
Query: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
RI T L +D +Q + V+ + S G GLCG D + ND
Sbjct: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2190
Query: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080
+G++ AP + W S + G D C + C C
Sbjct: 2191 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2235
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L + F+ CH VPPESF + + D C AL YVA C V IE
Sbjct: 2236 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2289
Query: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196
WR C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2290 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2347
Query: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245
+ C+P C C + A E W G C C+ G
Sbjct: 2348 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2406
Query: 3246 PASC-GLGEVCGLLPSGQHGC 3265
P SC GEV LLP+ C
Sbjct: 2407 PESCLRFGEVALLLPTKDPCC 2427
Score = 67.0 bits (162), Expect = 5e-10
Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779
N G+ P V ++ + L ++I + KV V+ PVS RI T
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
Query: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
Query: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
AP + W S + G D C + C C L +
Sbjct: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
Query: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
Query: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001
C +S Y+ C + C P +C PL P C+ EGC C G +L + C+
Sbjct: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
Query: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052
P C C + A E W G C C+ G P SC GE
Sbjct: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
Query: 2053 VCGLLPSGQHGC 2064
V LLP+ C
Sbjct: 2416 VALLLPTKDPCC 2427
Score = 65.9 bits (159), Expect = 1e-09
Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%)
Query: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057
T + Q C H+ G+++ + P P GIL + G C P
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2034
Query: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117
C C ++ D + +FDG Y+L+ + + LT
Sbjct: 2035 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2076
Query: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174
+ K+ N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2077 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2134
Query: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
L +D +Q + V+ + S G GLCG D + ND +G
Sbjct: 2135 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2192
Query: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283
++ AP + W S + G D C + C C L
Sbjct: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2236
Query: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343
+ F+ CH VPPESF + + D C AL YVA C V IE WR
Sbjct: 2237 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2291
Query: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397
C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2349
Query: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448
+ C+P C C + A E W G C C+ G P
Sbjct: 2350 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2408
Query: 4449 SC-GLGEVCGLLPSGQHGC 4466
SC GEV LLP+ C
Sbjct: 2409 SCLRFGEVALLLPTKDPCC 2427
>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2924
Score = 308 bits (790), Expect = 7e-83
Identities = 310/1217 (25%), Positives = 448/1217 (36%), Gaps = 192/1217 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 719
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 893
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 1762 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 1818
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 1875
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 1876 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 1933
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 1934 GVVIEDWRAQVGCEITC 1950
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 306 bits (785), Expect = 3e-82
Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%)
Query: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643
CV +C C YP G S C TC + G
Sbjct: 466 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 501
Query: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702
C AV C +GD H+TTFDG R+ F TC Y+LA++ + F V +N
Sbjct: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871
FGNSW+ + SP + GS P D C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 719
Query: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031
CVP QC C+ GV Y P + + C C G V+ C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 893
Query: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 4336 GVVIEDWRAQVGCEITC 4352
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 304 bits (778), Expect = 2e-81
Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%)
Query: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442
CV +C C YP G S C TC + G
Sbjct: 466 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 501
Query: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501
C AV C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670
FGNSW+ + SP + GS P + C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 719
Query: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830
CVP QC C+ G Y P + + C C G V+ C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 893
Query: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 3135 GVVIEDWRAQVGCEITC 3151
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 298 bits (762), Expect = 1e-79
Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%)
Query: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303
AP P S P P L+Q G G + PF CHA+V P F
Sbjct: 315 EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 369
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361
C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
CPASC P + E CV+GC C G + CV C C +GT + G
Sbjct: 430 IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 485
Query: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481
S D C+ C C G C+ A C AEC GD H
Sbjct: 486 SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 520
Query: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539
+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ ++
Sbjct: 521 FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575
Query: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596
+TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 576 DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 634
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648
+ L+V + GLCG +N + DD + G P W+ A C VS
Sbjct: 635 LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 692
Query: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708
PC Q + AC V+ T APC + P YF+ C DAC+ G P L
Sbjct: 693 SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 748
Query: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765
C +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 749 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 808
Query: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810
C EGC C D D CVP QC C G YP G+ P
Sbjct: 809 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 868
Query: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829
C+ R P G V TC++
Sbjct: 869 DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 928
Query: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859
G AC EEC + + CH C R C A
Sbjct: 929 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 988
Query: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916
G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 989 GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 1037
Query: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1097
Query: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1098 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1153
Query: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q GD
Sbjct: 1154 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
C S++AY C GVAV WRT CP C
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 280 bits (716), Expect = 3e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 254 bits (649), Expect = 2e-66
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 248 bits (634), Expect = 9e-65
Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%)
Query: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882
C PS + SC N C H C C+ G P ++ C WG H
Sbjct: 105 CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 159
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941
+FDG + G +Y L P + F++ N + G+ + R V++ +
Sbjct: 160 ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 214
Query: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001
G IH + +V G+ LP + R+ Q A ++ +++D V
Sbjct: 215 GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 269
Query: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053
+ + G GLCGN + +P +D V +G L + + SW+ AP P L
Sbjct: 270 IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 329
Query: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113
C P + EQ E L P PF CHA+V P F C D+C
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 380
Query: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171
GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C CPASC
Sbjct: 381 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 437
Query: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231
P + E CV+GC C G + CV C C +GT + GS D C+
Sbjct: 438 HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 494
Query: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291
C C G C+ A C AEC GD H+ T DG R+ F
Sbjct: 495 -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 531
Query: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347
TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ +TL+
Sbjct: 532 PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 586
Query: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406
L D + P+ D+ LS + V T G+ + +D + + L+V +
Sbjct: 587 GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458
GLCG +N + DD + G P W+ A C VS PC Q
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 703
Query: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518
+ AC V+ T APC + P YF+ C DAC+ G P LC +A Y C
Sbjct: 704 AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 759
Query: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569
+ G + R C C A Y C C +C L++PE C C
Sbjct: 760 RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 819
Query: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627
EGC C D D CVP QC C YP G + P G C C++ G +SC+
Sbjct: 820 EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 875
Query: 3628 PSSCGPHETCRPSG 3641
S P C P+G
Sbjct: 876 --SRAPAAAC-PAG 886
Score = 248 bits (634), Expect = 9e-65
Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897
AP P L C P + EQ E L P PF CHA+V
Sbjct: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 365
Query: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 366 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 425
Query: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015
Y C + CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 426 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 481
Query: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075
+ GS D C+ C C G C+ A C AEC
Sbjct: 482 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 516
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 517 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 571
Query: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 572 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 688
Query: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 745
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
P LC +A Y C+ G + R C C A Y C C +C L++PE
Sbjct: 746 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804
Query: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
C C EGC C D D CVP QC C YP G + P G
Sbjct: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 863
Query: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440
C C++ G +SC+ S P C P+G
Sbjct: 864 --HCHCKD-GVMSCD--SRAPAAAC-PAG 886
Score = 161 bits (408), Expect = 1e-38
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 115 bits (287), Expect = 2e-24
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1136 C 1136
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 1e-19
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 92.4 bits (228), Expect = 1e-17
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 5195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 5196 ERCSCSSSSGLTCQAAGCPPGR 5217
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 91.3 bits (225), Expect = 2e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 90.1 bits (222), Expect = 5e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2183
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2184 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2242
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2298
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2299 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2342
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2343 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2394
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2455 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2513 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 86.3 bits (212), Expect = 8e-16
Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 920 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 972
Query: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
S CT C + C A+GD HY T DG FDF G C+ L
Sbjct: 973 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012
Query: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
+F+V V N + S + + +++ + N + D +
Sbjct: 1013 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 1059
Query: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469
++++ P ++ Q G + CP P +E F + +
Sbjct: 1120 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1175
Query: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1176 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1231
Query: 3528 WRRPDFCPFQC 3538
WR P CP+ C
Sbjct: 1232 WRTPRLCPYDC 1242
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392
EGCVC G +L C+P +C C
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593
EGCVC G +L C+P +C C
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 84.7 bits (208), Expect = 2e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 84.3 bits (207), Expect = 3e-15
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 920 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 972
Query: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099
S CT C + C A+GD HY T DG F+F G C+ L
Sbjct: 973 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012
Query: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159
+F+V V N + S + + +++ + N + D +
Sbjct: 1013 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 1059
Query: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268
++++ P ++ Q G + CP P +E F + +
Sbjct: 1120 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1175
Query: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1176 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1231
Query: 2327 WRRPDFCPFQC 2337
WR P CP+ C
Sbjct: 1232 WRTPRLCPYDC 1242
Score = 83.6 bits (205), Expect = 5e-15
Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%)
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613
S P+LS EG A + + TCVP+ + C+
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 2063
Query: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662
C EG + S P P G LG C + C+ S D +
Sbjct: 2064 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2119
Query: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2120 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2179
Query: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2180 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2238
Query: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838
GLCG +GD +D +GS G A + F +SW+ VP S T P
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2296
Query: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
S C +D C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2297 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2338
Query: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958
+ C + YV+ C +E WR +CP C +S Y+ C C P
Sbjct: 2339 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2389
Query: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999
C DG EGC C G + + C+P +C C + GV E
Sbjct: 2390 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449
Query: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046
+ L C+ Q C +V + C +P + L TKDP
Sbjct: 2450 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507
Query: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075
C G+ TCRP + C P+Y C
Sbjct: 2508 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 82.0 bits (201), Expect = 1e-14
Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%)
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412
S P+LS EG A + + TCVP+ + C+
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 2063
Query: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461
C EG + S P P G LG C + C+ S D +
Sbjct: 2064 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2119
Query: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2120 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2179
Query: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2180 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2238
Query: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632
GLCG +GD +D +GS G A + F +SW+ VP S P
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2296
Query: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692
+C + +C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2297 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2336
Query: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752
+ C + YV+ C +E WR +CP C +S Y+ C C
Sbjct: 2337 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2385
Query: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793
P C DG EGC C G + + C+P +C C + A
Sbjct: 2386 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2444
Query: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845
E + L C+ Q C +V + C +P + L KDP
Sbjct: 2445 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2502
Query: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874
C G+ TCRP + C P+Y C
Sbjct: 2503 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 78.6 bits (192), Expect = 2e-13
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 67.0 bits (162), Expect = 5e-10
Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%)
Query: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856
T + Q C H+ G+++ + P P GIL G+ R
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2096
Query: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
G C P +E C ++ D + +FDG Y+L+ + + LT
Sbjct: 2097 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2146
Query: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971
+ K+ N G+ P V ++ + L ++I + KV V+ PVS
Sbjct: 2147 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2204
Query: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
RI T L +D +Q + V+ + S G GLCG D + ND
Sbjct: 2205 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2262
Query: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080
+G++ AP + W S + G D C + C C
Sbjct: 2263 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2307
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L + F+ CH VPPESF + + D C AL YVA C V IE
Sbjct: 2308 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2361
Query: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196
WR C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2362 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2419
Query: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245
+ C+P C C + A E W G C C+ G
Sbjct: 2420 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2478
Query: 3246 PASC-GLGEVCGLLPSGQHGC 3265
P SC GEV LLP+ C
Sbjct: 2479 PESCLRFGEVALLLPTKDPCC 2499
Score = 67.0 bits (162), Expect = 5e-10
Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779
N G+ P V ++ + L ++I + KV V+ PVS RI T
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2213
Query: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2214 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2271
Query: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
AP + W S + G D C + C C L +
Sbjct: 2272 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2315
Query: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2370
Query: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001
C +S Y+ C + C P +C PL P C+ EGC C G +L + C+
Sbjct: 2371 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2428
Query: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052
P C C + A E W G C C+ G P SC GE
Sbjct: 2429 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2487
Query: 2053 VCGLLPSGQHGC 2064
V LLP+ C
Sbjct: 2488 VALLLPTKDPCC 2499
Score = 65.9 bits (159), Expect = 1e-09
Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%)
Query: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057
T + Q C H+ G+++ + P P GIL + G C P
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2106
Query: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117
C C ++ D + +FDG Y+L+ + + LT
Sbjct: 2107 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2148
Query: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174
+ K+ N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2149 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2206
Query: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
L +D +Q + V+ + S G GLCG D + ND +G
Sbjct: 2207 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2264
Query: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283
++ AP + W S + G D C + C C L
Sbjct: 2265 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2308
Query: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343
+ F+ CH VPPESF + + D C AL YVA C V IE WR
Sbjct: 2309 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2363
Query: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397
C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2364 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2421
Query: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448
+ C+P C C + A E W G C C+ G P
Sbjct: 2422 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2480
Query: 4449 SC-GLGEVCGLLPSGQHGC 4466
SC GEV LLP+ C
Sbjct: 2481 SCLRFGEVALLLPTKDPCC 2499
>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 308 bits (790), Expect = 7e-83
Identities = 310/1217 (25%), Positives = 448/1217 (36%), Gaps = 192/1217 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 821
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 1762 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 1818
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 1875
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 1876 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 1933
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 1934 GVVIEDWRAQVGCEITC 1950
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 306 bits (785), Expect = 3e-82
Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%)
Query: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643
CV +C C YP G S C TC + G
Sbjct: 394 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
Query: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702
C AV C +GD H+TTFDG R+ F TC Y+LA++ + F V +N
Sbjct: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871
FGNSW+ + SP + GS P D C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
Query: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031
CVP QC C+ GV Y P + + C C G V+ C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
Query: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 4336 GVVIEDWRAQVGCEITC 4352
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 304 bits (778), Expect = 2e-81
Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%)
Query: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442
CV +C C YP G S C TC + G
Sbjct: 394 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
Query: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501
C AV C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670
FGNSW+ + SP + GS P + C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
Query: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830
CVP QC C+ G Y P + + C C G V+ C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
Query: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 3135 GVVIEDWRAQVGCEITC 3151
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 298 bits (762), Expect = 1e-79
Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%)
Query: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303
AP P S P P L+Q G G + PF CHA+V P F
Sbjct: 243 EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 297
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361
C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
CPASC P + E CV+GC C G + CV C C +GT + G
Sbjct: 358 IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 413
Query: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481
S D C+ C C G C+ A C AEC GD H
Sbjct: 414 SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 448
Query: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539
+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ ++
Sbjct: 449 FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
Query: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596
+TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 504 DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 562
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648
+ L+V + GLCG +N + DD + G P W+ A C VS
Sbjct: 563 LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 620
Query: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708
PC Q + AC V+ T APC + P YF+ C DAC+ G P L
Sbjct: 621 SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 676
Query: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765
C +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 677 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
Query: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810
C EGC C D D CVP QC C G YP G+ P
Sbjct: 737 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 796
Query: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829
C+ R P G V TC++
Sbjct: 797 DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 856
Query: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859
G AC EEC + + CH C R C A
Sbjct: 857 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 916
Query: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916
G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 917 GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 965
Query: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1025
Query: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1081
Query: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q GD
Sbjct: 1082 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
C S++AY C GVAV WRT CP C
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 280 bits (716), Expect = 3e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 254 bits (649), Expect = 2e-66
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 248 bits (634), Expect = 9e-65
Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%)
Query: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882
C PS + SC N C H C C+ G P ++ C WG H
Sbjct: 33 CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 87
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941
+FDG + G +Y L P + F++ N + G+ + R V++ +
Sbjct: 88 ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 142
Query: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001
G IH + +V G+ LP + R+ Q A ++ +++D V
Sbjct: 143 GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 197
Query: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053
+ + G GLCGN + +P +D V +G L + + SW+ AP P L
Sbjct: 198 IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 257
Query: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113
C P + EQ E L P PF CHA+V P F C D+C
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 308
Query: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171
GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C CPASC
Sbjct: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 365
Query: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231
P + E CV+GC C G + CV C C +GT + GS D C+
Sbjct: 366 HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 422
Query: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291
C C G C+ A C AEC GD H+ T DG R+ F
Sbjct: 423 -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 459
Query: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347
TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ +TL+
Sbjct: 460 PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
Query: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406
L D + P+ D+ LS + V T G+ + +D + + L+V +
Sbjct: 515 GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458
GLCG +N + DD + G P W+ A C VS PC Q
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 631
Query: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518
+ AC V+ T APC + P YF+ C DAC+ G P LC +A Y C
Sbjct: 632 AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 687
Query: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569
+ G + R C C A Y C C +C L++PE C C
Sbjct: 688 RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747
Query: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627
EGC C D D CVP QC C YP G + P G C C++ G +SC+
Sbjct: 748 EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 803
Query: 3628 PSSCGPHETCRPSG 3641
S P C P+G
Sbjct: 804 --SRAPAAAC-PAG 814
Score = 248 bits (634), Expect = 9e-65
Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897
AP P L C P + EQ E L P PF CHA+V
Sbjct: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
Query: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 294 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
Query: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015
Y C + CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 354 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
Query: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075
+ GS D C+ C C G C+ A C AEC
Sbjct: 410 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 445 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
Query: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 500 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
Query: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
P LC +A Y C+ G + R C C A Y C C +C L++PE
Sbjct: 674 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
Query: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
C C EGC C D D CVP QC C YP G + P G
Sbjct: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 791
Query: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440
C C++ G +SC+ S P C P+G
Sbjct: 792 --HCHCKD-GVMSCD--SRAPAAAC-PAG 814
Score = 161 bits (408), Expect = 1e-38
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 115 bits (287), Expect = 2e-24
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1136 C 1136
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 1e-19
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 92.4 bits (228), Expect = 1e-17
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 5195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 5196 ERCSCSSSSGLTCQAAGCPPGR 5217
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 91.3 bits (225), Expect = 2e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 90.1 bits (222), Expect = 5e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2226
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2227 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2270
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2271 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2322
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2383 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2441 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 86.3 bits (212), Expect = 8e-16
Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 848 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
Query: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
S CT C + C A+GD HY T DG FDF G C+ L
Sbjct: 901 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
Query: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
+F+V V N + S + + +++ + N + D +
Sbjct: 941 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
Query: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469
++++ P ++ Q G + CP P +E F + +
Sbjct: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
Query: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
Query: 3528 WRRPDFCPFQC 3538
WR P CP+ C
Sbjct: 1160 WRTPRLCPYDC 1170
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392
EGCVC G +L C+P +C C
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593
EGCVC G +L C+P +C C
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 84.7 bits (208), Expect = 2e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 84.3 bits (207), Expect = 3e-15
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 848 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
Query: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099
S CT C + C A+GD HY T DG F+F G C+ L
Sbjct: 901 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
Query: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159
+F+V V N + S + + +++ + N + D +
Sbjct: 941 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
Query: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268
++++ P ++ Q G + CP P +E F + +
Sbjct: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
Query: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
Query: 2327 WRRPDFCPFQC 2337
WR P CP+ C
Sbjct: 1160 WRTPRLCPYDC 1170
Score = 83.6 bits (205), Expect = 5e-15
Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%)
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613
S P+LS EG A + + TCVP+ + C+
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
Query: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662
C EG + S P P G LG C + C+ S D +
Sbjct: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
Query: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
Query: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
Query: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838
GLCG +GD +D +GS G A + F +SW+ VP S T P
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
Query: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
S C +D C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2225 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2266
Query: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958
+ C + YV+ C +E WR +CP C +S Y+ C C P
Sbjct: 2267 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2317
Query: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999
C DG EGC C G + + C+P +C C + GV E
Sbjct: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
Query: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046
+ L C+ Q C +V + C +P + L TKDP
Sbjct: 2378 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
Query: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075
C G+ TCRP + C P+Y C
Sbjct: 2436 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 82.0 bits (201), Expect = 1e-14
Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%)
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412
S P+LS EG A + + TCVP+ + C+
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
Query: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461
C EG + S P P G LG C + C+ S D +
Sbjct: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
Query: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
Query: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
Query: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632
GLCG +GD +D +GS G A + F +SW+ VP S P
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
Query: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692
+C + +C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2225 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2264
Query: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752
+ C + YV+ C +E WR +CP C +S Y+ C C
Sbjct: 2265 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2313
Query: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793
P C DG EGC C G + + C+P +C C + A
Sbjct: 2314 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372
Query: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845
E + L C+ Q C +V + C +P + L KDP
Sbjct: 2373 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2430
Query: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874
C G+ TCRP + C P+Y C
Sbjct: 2431 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 78.6 bits (192), Expect = 2e-13
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 67.0 bits (162), Expect = 5e-10
Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%)
Query: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856
T + Q C H+ G+++ + P P GIL G+ R
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2024
Query: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
G C P +E C ++ D + +FDG Y+L+ + + LT
Sbjct: 2025 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2074
Query: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971
+ K+ N G+ P V ++ + L ++I + KV V+ PVS
Sbjct: 2075 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2132
Query: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
RI T L +D +Q + V+ + S G GLCG D + ND
Sbjct: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2190
Query: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080
+G++ AP + W S + G D C + C C
Sbjct: 2191 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2235
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L + F+ CH VPPESF + + D C AL YVA C V IE
Sbjct: 2236 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2289
Query: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196
WR C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2290 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2347
Query: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245
+ C+P C C + A E W G C C+ G
Sbjct: 2348 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2406
Query: 3246 PASC-GLGEVCGLLPSGQHGC 3265
P SC GEV LLP+ C
Sbjct: 2407 PESCLRFGEVALLLPTKDPCC 2427
Score = 67.0 bits (162), Expect = 5e-10
Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779
N G+ P V ++ + L ++I + KV V+ PVS RI T
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
Query: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
Query: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
AP + W S + G D C + C C L +
Sbjct: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
Query: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
Query: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001
C +S Y+ C + C P +C PL P C+ EGC C G +L + C+
Sbjct: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
Query: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052
P C C + A E W G C C+ G P SC GE
Sbjct: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
Query: 2053 VCGLLPSGQHGC 2064
V LLP+ C
Sbjct: 2416 VALLLPTKDPCC 2427
Score = 65.9 bits (159), Expect = 1e-09
Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%)
Query: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057
T + Q C H+ G+++ + P P GIL + G C P
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2034
Query: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117
C C ++ D + +FDG Y+L+ + + LT
Sbjct: 2035 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2076
Query: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174
+ K+ N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2077 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2134
Query: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
L +D +Q + V+ + S G GLCG D + ND +G
Sbjct: 2135 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2192
Query: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283
++ AP + W S + G D C + C C L
Sbjct: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2236
Query: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343
+ F+ CH VPPESF + + D C AL YVA C V IE WR
Sbjct: 2237 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2291
Query: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397
C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2349
Query: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448
+ C+P C C + A E W G C C+ G P
Sbjct: 2350 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2408
Query: 4449 SC-GLGEVCGLLPSGQHGC 4466
SC GEV LLP+ C
Sbjct: 2409 SCLRFGEVALLLPTKDPCC 2427
>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 308 bits (790), Expect = 7e-83
Identities = 310/1217 (25%), Positives = 448/1217 (36%), Gaps = 192/1217 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 719
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 893
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 1762 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 1818
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 1875
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 1876 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 1933
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 1934 GVVIEDWRAQVGCEITC 1950
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 306 bits (785), Expect = 3e-82
Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%)
Query: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643
CV +C C YP G S C TC + G
Sbjct: 466 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 501
Query: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702
C AV C +GD H+TTFDG R+ F TC Y+LA++ + F V +N
Sbjct: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871
FGNSW+ + SP + GS P D C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 719
Query: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031
CVP QC C+ GV Y P + + C C G V+ C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 893
Query: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 4336 GVVIEDWRAQVGCEITC 4352
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 304 bits (778), Expect = 2e-81
Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%)
Query: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442
CV +C C YP G S C TC + G
Sbjct: 466 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 501
Query: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501
C AV C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670
FGNSW+ + SP + GS P + C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 719
Query: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830
CVP QC C+ G Y P + + C C G V+ C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 893
Query: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 3135 GVVIEDWRAQVGCEITC 3151
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 298 bits (762), Expect = 1e-79
Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%)
Query: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303
AP P S P P L+Q G G + PF CHA+V P F
Sbjct: 315 EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 369
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361
C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
CPASC P + E CV+GC C G + CV C C +GT + G
Sbjct: 430 IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 485
Query: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481
S D C+ C C G C+ A C AEC GD H
Sbjct: 486 SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 520
Query: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539
+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ ++
Sbjct: 521 FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575
Query: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596
+TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 576 DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 634
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648
+ L+V + GLCG +N + DD + G P W+ A C VS
Sbjct: 635 LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 692
Query: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708
PC Q + AC V+ T APC + P YF+ C DAC+ G P L
Sbjct: 693 SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 748
Query: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765
C +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 749 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 808
Query: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810
C EGC C D D CVP QC C G YP G+ P
Sbjct: 809 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 868
Query: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829
C+ R P G V TC++
Sbjct: 869 DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 928
Query: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859
G AC EEC + + CH C R C A
Sbjct: 929 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 988
Query: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916
G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 989 GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 1037
Query: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1097
Query: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1098 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1153
Query: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q GD
Sbjct: 1154 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
C S++AY C GVAV WRT CP C
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 280 bits (716), Expect = 3e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 254 bits (649), Expect = 2e-66
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 248 bits (634), Expect = 9e-65
Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%)
Query: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882
C PS + SC N C H C C+ G P ++ C WG H
Sbjct: 105 CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 159
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941
+FDG + G +Y L P + F++ N + G+ + R V++ +
Sbjct: 160 ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 214
Query: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001
G IH + +V G+ LP + R+ Q A ++ +++D V
Sbjct: 215 GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 269
Query: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053
+ + G GLCGN + +P +D V +G L + + SW+ AP P L
Sbjct: 270 IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 329
Query: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113
C P + EQ E L P PF CHA+V P F C D+C
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 380
Query: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171
GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C CPASC
Sbjct: 381 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 437
Query: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231
P + E CV+GC C G + CV C C +GT + GS D C+
Sbjct: 438 HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 494
Query: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291
C C G C+ A C AEC GD H+ T DG R+ F
Sbjct: 495 -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 531
Query: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347
TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ +TL+
Sbjct: 532 PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 586
Query: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406
L D + P+ D+ LS + V T G+ + +D + + L+V +
Sbjct: 587 GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458
GLCG +N + DD + G P W+ A C VS PC Q
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 703
Query: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518
+ AC V+ T APC + P YF+ C DAC+ G P LC +A Y C
Sbjct: 704 AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 759
Query: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569
+ G + R C C A Y C C +C L++PE C C
Sbjct: 760 RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 819
Query: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627
EGC C D D CVP QC C YP G + P G C C++ G +SC+
Sbjct: 820 EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 875
Query: 3628 PSSCGPHETCRPSG 3641
S P C P+G
Sbjct: 876 --SRAPAAAC-PAG 886
Score = 248 bits (634), Expect = 9e-65
Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897
AP P L C P + EQ E L P PF CHA+V
Sbjct: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 365
Query: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 366 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 425
Query: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015
Y C + CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 426 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 481
Query: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075
+ GS D C+ C C G C+ A C AEC
Sbjct: 482 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 516
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 517 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 571
Query: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 572 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 688
Query: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 745
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
P LC +A Y C+ G + R C C A Y C C +C L++PE
Sbjct: 746 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804
Query: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
C C EGC C D D CVP QC C YP G + P G
Sbjct: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 863
Query: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440
C C++ G +SC+ S P C P+G
Sbjct: 864 --HCHCKD-GVMSCD--SRAPAAAC-PAG 886
Score = 161 bits (408), Expect = 1e-38
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 115 bits (287), Expect = 2e-24
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1136 C 1136
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 1e-19
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 92.4 bits (228), Expect = 1e-17
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 5195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 5196 ERCSCSSSSGLTCQAAGCPPGR 5217
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 91.3 bits (225), Expect = 2e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 90.1 bits (222), Expect = 5e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2183
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2184 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2242
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2298
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2299 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2342
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2343 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2394
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2455 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2513 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 86.3 bits (212), Expect = 8e-16
Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 920 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 972
Query: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
S CT C + C A+GD HY T DG FDF G C+ L
Sbjct: 973 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012
Query: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
+F+V V N + S + + +++ + N + D +
Sbjct: 1013 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 1059
Query: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469
++++ P ++ Q G + CP P +E F + +
Sbjct: 1120 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1175
Query: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1176 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1231
Query: 3528 WRRPDFCPFQC 3538
WR P CP+ C
Sbjct: 1232 WRTPRLCPYDC 1242
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392
EGCVC G +L C+P +C C
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593
EGCVC G +L C+P +C C
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 84.7 bits (208), Expect = 2e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 84.3 bits (207), Expect = 3e-15
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 920 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 972
Query: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099
S CT C + C A+GD HY T DG F+F G C+ L
Sbjct: 973 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012
Query: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159
+F+V V N + S + + +++ + N + D +
Sbjct: 1013 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 1059
Query: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268
++++ P ++ Q G + CP P +E F + +
Sbjct: 1120 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1175
Query: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1176 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1231
Query: 2327 WRRPDFCPFQC 2337
WR P CP+ C
Sbjct: 1232 WRTPRLCPYDC 1242
Score = 83.6 bits (205), Expect = 5e-15
Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%)
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613
S P+LS EG A + + TCVP+ + C+
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 2063
Query: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662
C EG + S P P G LG C + C+ S D +
Sbjct: 2064 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2119
Query: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2120 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2179
Query: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2180 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2238
Query: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838
GLCG +GD +D +GS G A + F +SW+ VP S T P
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2296
Query: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
S C +D C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2297 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2338
Query: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958
+ C + YV+ C +E WR +CP C +S Y+ C C P
Sbjct: 2339 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2389
Query: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999
C DG EGC C G + + C+P +C C + GV E
Sbjct: 2390 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449
Query: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046
+ L C+ Q C +V + C +P + L TKDP
Sbjct: 2450 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507
Query: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075
C G+ TCRP + C P+Y C
Sbjct: 2508 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 82.0 bits (201), Expect = 1e-14
Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%)
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412
S P+LS EG A + + TCVP+ + C+
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 2063
Query: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461
C EG + S P P G LG C + C+ S D +
Sbjct: 2064 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2119
Query: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2120 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2179
Query: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2180 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2238
Query: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632
GLCG +GD +D +GS G A + F +SW+ VP S P
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2296
Query: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692
+C + +C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2297 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2336
Query: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752
+ C + YV+ C +E WR +CP C +S Y+ C C
Sbjct: 2337 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2385
Query: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793
P C DG EGC C G + + C+P +C C + A
Sbjct: 2386 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2444
Query: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845
E + L C+ Q C +V + C +P + L KDP
Sbjct: 2445 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2502
Query: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874
C G+ TCRP + C P+Y C
Sbjct: 2503 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 78.6 bits (192), Expect = 2e-13
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 67.0 bits (162), Expect = 5e-10
Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%)
Query: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856
T + Q C H+ G+++ + P P GIL G+ R
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2096
Query: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
G C P +E C ++ D + +FDG Y+L+ + + LT
Sbjct: 2097 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2146
Query: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971
+ K+ N G+ P V ++ + L ++I + KV V+ PVS
Sbjct: 2147 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2204
Query: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
RI T L +D +Q + V+ + S G GLCG D + ND
Sbjct: 2205 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2262
Query: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080
+G++ AP + W S + G D C + C C
Sbjct: 2263 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2307
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L + F+ CH VPPESF + + D C AL YVA C V IE
Sbjct: 2308 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2361
Query: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196
WR C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2362 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2419
Query: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245
+ C+P C C + A E W G C C+ G
Sbjct: 2420 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2478
Query: 3246 PASC-GLGEVCGLLPSGQHGC 3265
P SC GEV LLP+ C
Sbjct: 2479 PESCLRFGEVALLLPTKDPCC 2499
Score = 67.0 bits (162), Expect = 5e-10
Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779
N G+ P V ++ + L ++I + KV V+ PVS RI T
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2213
Query: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2214 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2271
Query: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
AP + W S + G D C + C C L +
Sbjct: 2272 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2315
Query: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2370
Query: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001
C +S Y+ C + C P +C PL P C+ EGC C G +L + C+
Sbjct: 2371 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2428
Query: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052
P C C + A E W G C C+ G P SC GE
Sbjct: 2429 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2487
Query: 2053 VCGLLPSGQHGC 2064
V LLP+ C
Sbjct: 2488 VALLLPTKDPCC 2499
Score = 65.9 bits (159), Expect = 1e-09
Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%)
Query: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057
T + Q C H+ G+++ + P P GIL + G C P
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2106
Query: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117
C C ++ D + +FDG Y+L+ + + LT
Sbjct: 2107 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2148
Query: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174
+ K+ N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2149 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2206
Query: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
L +D +Q + V+ + S G GLCG D + ND +G
Sbjct: 2207 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2264
Query: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283
++ AP + W S + G D C + C C L
Sbjct: 2265 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2308
Query: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343
+ F+ CH VPPESF + + D C AL YVA C V IE WR
Sbjct: 2309 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2363
Query: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397
C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2364 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2421
Query: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448
+ C+P C C + A E W G C C+ G P
Sbjct: 2422 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2480
Query: 4449 SC-GLGEVCGLLPSGQHGC 4466
SC GEV LLP+ C
Sbjct: 2481 SCLRFGEVALLLPTKDPCC 2499
>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
Length = 2852
Score = 308 bits (790), Expect = 7e-83
Identities = 310/1217 (25%), Positives = 448/1217 (36%), Gaps = 192/1217 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 49 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 105
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 106 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 163
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 164 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 214
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 215 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 274
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 275 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 332
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 333 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 392
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 437
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 438 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 647
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 821
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 1762 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 1818
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 1875
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 1876 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 1933
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 1934 GVVIEDWRAQVGCEITC 1950
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 306 bits (785), Expect = 3e-82
Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%)
Query: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643
CV +C C YP G S C TC + G
Sbjct: 394 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
Query: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702
C AV C +GD H+TTFDG R+ F TC Y+LA++ + F V +N
Sbjct: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871
FGNSW+ + SP + GS P D C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
Query: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031
CVP QC C+ GV Y P + + C C G V+ C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
Query: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 4336 GVVIEDWRAQVGCEITC 4352
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 304 bits (778), Expect = 2e-81
Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%)
Query: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442
CV +C C YP G S C TC + G
Sbjct: 394 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 429
Query: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501
C AV C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 430 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 485
Query: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553
G + VQ + L + R+ D+ L P +IR
Sbjct: 486 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 540
Query: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 541 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 598
Query: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670
FGNSW+ + SP + GS P + C L+ + C +L+
Sbjct: 599 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 647
Query: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 648 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 704
Query: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 705 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 764
Query: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830
CVP QC C+ G Y P + + C C G V+ C +C GQV
Sbjct: 765 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 821
Query: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851
C+ LS + PC HG C
Sbjct: 822 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 881
Query: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 882 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 939
Query: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 940 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 985
Query: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 986 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1045
Query: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076
D N+ P + +G SW A EC + C + L +
Sbjct: 1046 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1097
Query: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1098 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1154
Query: 3135 GVVIEDWRAQVGCEITC 3151
GV + DWR C C
Sbjct: 1155 GVAV-DWRTPRLCPYDC 1170
Score = 298 bits (762), Expect = 1e-79
Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%)
Query: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303
AP P S P P L+Q G G + PF CHA+V P F
Sbjct: 243 EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 297
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361
C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C
Sbjct: 298 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 357
Query: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
CPASC P + E CV+GC C G + CV C C +GT + G
Sbjct: 358 IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 413
Query: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481
S D C+ C C G C+ A C AEC GD H
Sbjct: 414 SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 448
Query: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539
+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ ++
Sbjct: 449 FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 503
Query: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596
+TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 504 DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 562
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648
+ L+V + GLCG +N + DD + G P W+ A C VS
Sbjct: 563 LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 620
Query: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708
PC Q + AC V+ T APC + P YF+ C DAC+ G P L
Sbjct: 621 SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 676
Query: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765
C +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 677 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 736
Query: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810
C EGC C D D CVP QC C G YP G+ P
Sbjct: 737 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 796
Query: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829
C+ R P G V TC++
Sbjct: 797 DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 856
Query: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859
G AC EEC + + CH C R C A
Sbjct: 857 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 916
Query: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916
G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 917 GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 965
Query: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 966 KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1025
Query: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1026 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1081
Query: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q GD
Sbjct: 1082 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
C S++AY C GVAV WRT CP C
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 280 bits (716), Expect = 3e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 60 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 114
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 115 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 163
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 164 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 221
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 222 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 279
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 280 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 392
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 393 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 443
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 444 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 483
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 484 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 542
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 603 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 658
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 659 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 716
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 717 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 776
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 777 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 814
Score = 254 bits (649), Expect = 2e-66
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 44 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 102
Query: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 103 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 156
Query: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 157 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 215
Query: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 216 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 273
Query: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 274 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 333
Query: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 334 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 393
Query: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
CV +C C G YP PG + C C G
Sbjct: 394 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 428
Query: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 429 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 484
Query: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954
G + +L + V+L Q V + + +P ++ L
Sbjct: 485 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 544
Query: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 545 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 604
Query: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 605 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 659
Query: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 660 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 717
Query: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 718 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 777
Query: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218
P S + S C C S AA CP G+V
Sbjct: 778 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 816
Score = 248 bits (634), Expect = 9e-65
Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%)
Query: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882
C PS + SC N C H C C+ G P ++ C WG H
Sbjct: 33 CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 87
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941
+FDG + G +Y L P + F++ N + G+ + R V++ +
Sbjct: 88 ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 142
Query: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001
G IH + +V G+ LP + R+ Q A ++ +++D V
Sbjct: 143 GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 197
Query: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053
+ + G GLCGN + +P +D V +G L + + SW+ AP P L
Sbjct: 198 IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 257
Query: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113
C P + EQ E L P PF CHA+V P F C D+C
Sbjct: 258 PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 308
Query: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171
GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C CPASC
Sbjct: 309 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 365
Query: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231
P + E CV+GC C G + CV C C +GT + GS D C+
Sbjct: 366 HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 422
Query: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291
C C G C+ A C AEC GD H+ T DG R+ F
Sbjct: 423 -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 459
Query: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347
TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ +TL+
Sbjct: 460 PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 514
Query: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406
L D + P+ D+ LS + V T G+ + +D + + L+V +
Sbjct: 515 GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 573
Query: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458
GLCG +N + DD + G P W+ A C VS PC Q
Sbjct: 574 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 631
Query: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518
+ AC V+ T APC + P YF+ C DAC+ G P LC +A Y C
Sbjct: 632 AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 687
Query: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569
+ G + R C C A Y C C +C L++PE C C
Sbjct: 688 RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 747
Query: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627
EGC C D D CVP QC C YP G + P G C C++ G +SC+
Sbjct: 748 EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 803
Query: 3628 PSSCGPHETCRPSG 3641
S P C P+G
Sbjct: 804 --SRAPAAAC-PAG 814
Score = 248 bits (634), Expect = 9e-65
Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 73 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 127
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 128 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 182
Query: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 183 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 242
Query: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897
AP P L C P + EQ E L P PF CHA+V
Sbjct: 243 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 293
Query: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 294 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 353
Query: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015
Y C + CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 354 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 409
Query: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075
+ GS D C+ C C G C+ A C AEC
Sbjct: 410 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 444
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 445 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 499
Query: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 500 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 558
Query: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 559 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 616
Query: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 617 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 673
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
P LC +A Y C+ G + R C C A Y C C +C L++PE
Sbjct: 674 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 732
Query: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
C C EGC C D D CVP QC C YP G + P G
Sbjct: 733 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 791
Query: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440
C C++ G +SC+ S P C P+G
Sbjct: 792 --HCHCKD-GVMSCD--SRAPAAAC-PAG 814
Score = 161 bits (408), Expect = 1e-38
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 30 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 89
Query: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 90 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 147
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 148 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 205
Query: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 206 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 265
Query: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 266 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 323
Query: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 324 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 383
Query: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 384 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 438
Query: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 439 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 482
Query: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336
+ ++V + VTLT V + +P + + R
Sbjct: 483 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 542
Query: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 543 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 590
Score = 115 bits (287), Expect = 2e-24
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 798 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 854
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 855 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 911
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 912 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 945
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 946 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 996
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 997 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1056
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1057 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1110
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1111 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1169
Query: 1136 C 1136
C
Sbjct: 1170 C 1170
Score = 98.6 bits (244), Expect = 1e-19
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 895 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 950
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 951 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1001
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1002 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1061
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1062 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1114
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1115 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1170
Score = 92.4 bits (228), Expect = 1e-17
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2006
Query: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2007 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2053
Query: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2054 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2108
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2109 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2168
Query: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2169 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2226
Query: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2227 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2270
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2271 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2326
Query: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 5195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2327 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2385
Query: 5196 ERCSCSSSSGLTCQAAGCPPGR 5217
+ C + + GCP R
Sbjct: 2386 QH-QCQAPDTIVPVDLGCPSPR 2406
Score = 91.3 bits (225), Expect = 2e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 1962 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2021
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2022 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2079
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2080 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2136
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2137 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2196
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2243
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2244 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2296
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2297 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2354
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2355 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2389
Score = 90.1 bits (222), Expect = 5e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 1992 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2051
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2052 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2111
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2112 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2170
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2171 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2226
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2227 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2270
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2271 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2322
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2323 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2382
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2383 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2440
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2441 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 86.3 bits (212), Expect = 8e-16
Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 848 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
Query: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
S CT C + C A+GD HY T DG FDF G C+ L
Sbjct: 901 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
Query: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
+F+V V N + S + + +++ + N + D +
Sbjct: 941 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
Query: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469
++++ P ++ Q G + CP P +E F + +
Sbjct: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
Query: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
Query: 3528 WRRPDFCPFQC 3538
WR P CP+ C
Sbjct: 1160 WRTPRLCPYDC 1170
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392
EGCVC G +L C+P +C C
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593
EGCVC G +L C+P +C C
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCAC 2363
Score = 84.7 bits (208), Expect = 2e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2012 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2068
Query: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2069 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2122
Query: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2123 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2169
Query: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2170 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2222
Query: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2223 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2277
Query: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2278 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2335
Query: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2336 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2390
Score = 84.3 bits (207), Expect = 3e-15
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 848 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 900
Query: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099
S CT C + C A+GD HY T DG F+F G C+ L
Sbjct: 901 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 940
Query: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159
+F+V V N + S + + +++ + N + D +
Sbjct: 941 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 987
Query: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 988 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1047
Query: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268
++++ P ++ Q G + CP P +E F + +
Sbjct: 1048 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1103
Query: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1104 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1159
Query: 2327 WRRPDFCPFQC 2337
WR P CP+ C
Sbjct: 1160 WRTPRLCPYDC 1170
Score = 83.6 bits (205), Expect = 5e-15
Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%)
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613
S P+LS EG A + + TCVP+ + C+
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
Query: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662
C EG + S P P G LG C + C+ S D +
Sbjct: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
Query: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
Query: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
Query: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838
GLCG +GD +D +GS G A + F +SW+ VP S T P
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
Query: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
S C +D C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2225 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2266
Query: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958
+ C + YV+ C +E WR +CP C +S Y+ C C P
Sbjct: 2267 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2317
Query: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999
C DG EGC C G + + C+P +C C + GV E
Sbjct: 2318 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2377
Query: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046
+ L C+ Q C +V + C +P + L TKDP
Sbjct: 2378 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2435
Query: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075
C G+ TCRP + C P+Y C
Sbjct: 2436 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 82.0 bits (201), Expect = 1e-14
Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%)
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412
S P+LS EG A + + TCVP+ + C+
Sbjct: 1953 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 1991
Query: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461
C EG + S P P G LG C + C+ S D +
Sbjct: 1992 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2047
Query: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2048 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2107
Query: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2108 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2166
Query: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632
GLCG +GD +D +GS G A + F +SW+ VP S P
Sbjct: 2167 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2224
Query: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692
+C + +C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2225 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2264
Query: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752
+ C + YV+ C +E WR +CP C +S Y+ C C
Sbjct: 2265 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2313
Query: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793
P C DG EGC C G + + C+P +C C + A
Sbjct: 2314 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2372
Query: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845
E + L C+ Q C +V + C +P + L KDP
Sbjct: 2373 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2430
Query: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874
C G+ TCRP + C P+Y C
Sbjct: 2431 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2469
Score = 78.6 bits (192), Expect = 2e-13
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 1983 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2036
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2037 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2096
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2097 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2154
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2155 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2196
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2197 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2246
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2247 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2297
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2298 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2357
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2358 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2402
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2403 PSPRPESCLRFGE 2415
Score = 67.0 bits (162), Expect = 5e-10
Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%)
Query: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856
T + Q C H+ G+++ + P P GIL G+ R
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2024
Query: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
G C P +E C ++ D + +FDG Y+L+ + + LT
Sbjct: 2025 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2074
Query: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971
+ K+ N G+ P V ++ + L ++I + KV V+ PVS
Sbjct: 2075 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2132
Query: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
RI T L +D +Q + V+ + S G GLCG D + ND
Sbjct: 2133 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2190
Query: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080
+G++ AP + W S + G D C + C C
Sbjct: 2191 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2235
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L + F+ CH VPPESF + + D C AL YVA C V IE
Sbjct: 2236 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2289
Query: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196
WR C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2290 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2347
Query: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245
+ C+P C C + A E W G C C+ G
Sbjct: 2348 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2406
Query: 3246 PASC-GLGEVCGLLPSGQHGC 3265
P SC GEV LLP+ C
Sbjct: 2407 PESCLRFGEVALLLPTKDPCC 2427
Score = 67.0 bits (162), Expect = 5e-10
Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2029 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2083
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779
N G+ P V ++ + L ++I + KV V+ PVS RI T
Sbjct: 2084 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2141
Query: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2142 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2199
Query: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
AP + W S + G D C + C C L +
Sbjct: 2200 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2243
Query: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2244 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2298
Query: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001
C +S Y+ C + C P +C PL P C+ EGC C G +L + C+
Sbjct: 2299 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2356
Query: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052
P C C + A E W G C C+ G P SC GE
Sbjct: 2357 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2415
Query: 2053 VCGLLPSGQHGC 2064
V LLP+ C
Sbjct: 2416 VALLLPTKDPCC 2427
Score = 65.9 bits (159), Expect = 1e-09
Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%)
Query: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057
T + Q C H+ G+++ + P P GIL + G C P
Sbjct: 1977 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2034
Query: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117
C C ++ D + +FDG Y+L+ + + LT
Sbjct: 2035 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2076
Query: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174
+ K+ N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2077 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2134
Query: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
L +D +Q + V+ + S G GLCG D + ND +G
Sbjct: 2135 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2192
Query: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283
++ AP + W S + G D C + C C L
Sbjct: 2193 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2236
Query: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343
+ F+ CH VPPESF + + D C AL YVA C V IE WR
Sbjct: 2237 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2291
Query: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397
C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2292 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2349
Query: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448
+ C+P C C + A E W G C C+ G P
Sbjct: 2350 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2408
Query: 4449 SC-GLGEVCGLLPSGQHGC 4466
SC GEV LLP+ C
Sbjct: 2409 SCLRFGEVALLLPTKDPCC 2427
>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
Length = 2924
Score = 308 bits (790), Expect = 7e-83
Identities = 310/1217 (25%), Positives = 448/1217 (36%), Gaps = 192/1217 (15%)
Query: 831 HQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLL 890
H C ++ G RC + + P+R C+ G H +FDG + G +Y L
Sbjct: 121 HPAFCDCRRFNATGPRCQM---VYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTL 177
Query: 891 VGSCGQNAALPAFRVLVENEHR-GSQTVSYTRAVR---VEARGVKVAVRREYPG-QVLVD 945
VG +F + V N+ + GS + +RAV V + + +A + G +V +
Sbjct: 178 VGRHEPEGQ--SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLP 235
Query: 946 DVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGN 1005
V+ Q G V +VR T+ +D + V K+ GLCGN
Sbjct: 236 HVMGSARLQQLAGYV---------IVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGN 286
Query: 1006 FNGDPADDLALRGGGQAANALAFGNSWQEETR---PGCGATEPGDCPKLDSLVAQQLQSK 1062
N DP DDL G + + F +SWQE+ PG + P L
Sbjct: 287 NNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVY 346
Query: 1063 NECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGAT 1122
+C L P PF CH+ + P C D C G C ALA YA AC AG
Sbjct: 347 EQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRP 404
Query: 1123 VHPWRSE-ELCPLSCPPHSH-YEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSG 1180
+ WR++ C + C + Y C CP SC C +GC C G
Sbjct: 405 LQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFED 464
Query: 1181 ESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGG 1240
C+ A C C GT +PPG C++ C C G C ++ C
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--CNT-CTCTSGKW-ECSTAVC----------- 509
Query: 1241 SLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 1300
+ C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 510 --------PAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 1301 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 1352
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 1353 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQA 1409
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 1410 GNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTG 1469
FGNSW+ + SP + +P P C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLVSGSPLDP----------CDVHLQAASYSVQACSVLTGEM- 719
Query: 1470 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCP 1529
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 1530 MECPPNSHYELCADTCSLGCSALSAPPQC---------QDGCAEGCQCDSGFLYNGQA-- 1578
+ C + Y C C C L++P C +D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 1579 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEH----SCKPGQV----- 1629
CVP QC C+ GV Y P + + C C G M C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDGV-MSCDSRAPAAACPAGQVFVNCS 893
Query: 1630 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 1650
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 1651 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 1701
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 1702 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 1762 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 1818
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 1875
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 1876 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 1933
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 1934 GVVIEDWRAQVGCEITC 1950
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 306 bits (785), Expect = 3e-82
Identities = 321/1217 (26%), Positives = 449/1217 (36%), Gaps = 193/1217 (15%)
Query: 3239 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 3296
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 3297 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 3355
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 3356 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 3415
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 3416 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 3469
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 3470 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 3525
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 3526 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 3583
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 3584 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 3643
CV +C C YP G S C TC + G
Sbjct: 466 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 501
Query: 3644 LGC-VAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 3702
C AV C +GD H+TTFDG R+ F TC Y+LA++ + F V +N
Sbjct: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 3703 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 3754
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 3755 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 3811
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 3812 GNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTG 3871
FGNSW+ + SP + GS P D C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 719
Query: 3872 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCP 3931
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 3932 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 3980
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 3981 CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 4031
CVP QC C+ GV Y P + + C C G V+ C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 893
Query: 4032 -------------CQPSGGILSCVTKDPC------------HGVTC-------------- 4052
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 4053 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 4103
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 4104 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 4163
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 4164 ALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 4220
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 4221 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 4277
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 4278 GFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 4335
C L S F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 4336 GVVIEDWRAQVGCEITC 4352
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 304 bits (778), Expect = 2e-81
Identities = 319/1217 (26%), Positives = 448/1217 (36%), Gaps = 193/1217 (15%)
Query: 2038 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCE 2095
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 2096 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 2154
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 2155 GVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNY 2214
G+ V LP + S L+G V+V S +LA+DG S V +++ G GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 2215 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 2268
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 2269 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 2324
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 2325 REWRRP-DFCPFQCPAHSH-YELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGD 2382
+ WR C C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 2383 TCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGS 2442
CV +C C YP G S C TC + G
Sbjct: 466 GCVAPAECPCEFHGTLYPPG---------------------SVVKEDCN---TCTCTSGK 501
Query: 2443 LGC-VAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAW 2501
C AV C +GD H+TTFDGRR+ F TC Y+LA++ + F V +N
Sbjct: 502 WECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSS----GTFTVTLQNAPC 557
Query: 2502 GNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKL--------PVVLANGQIRASQH 2553
G + VQ + L + R+ D+ L P +IR
Sbjct: 558 GLNQDGA----CVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLS- 612
Query: 2554 GSDVVIETDFGLRVAYD---LVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQA 2610
+ + T+ G+RV YD L Y++ V + + GLCG +NG+ +DDF P G
Sbjct: 613 SVFLRVRTNVGVRVLYDREGLRLYLQ--VDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPE 670
Query: 2611 GNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTG 2670
FGNSW+ + SP + GS P + C L+ + C +L+
Sbjct: 671 STPQLFGNSWKTLSACSPLV------SGS----PLDPCDVHLQAASYSVQACSVLTGEM- 719
Query: 2671 PLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCP 2730
+ C + P + C D C G LC+ + Y C+ G V+ C
Sbjct: 720 -FAPCSAFLSPVPYFEQCRRDACRCG--QPCLCATLAHYAHLCRRHGLPVDFRARLPACA 776
Query: 2731 MECPQNSHYELCADTCSLGCSALSAPLQC---------PDGCAEGCQCDSGFLYNGQA-- 2779
+ C + Y C C C L++P C D C EGC C + QA
Sbjct: 777 LSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADL 836
Query: 2780 CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEH----SCKPGQV----- 2830
CVP QC C+ G Y P + + C C G V+ C +C GQV
Sbjct: 837 CVPRNQCSCHFQGVDYPPGDSDI--PSLGHCHCKDG-VMSCDSRAPAAACPAGQVFVNCS 893
Query: 2831 -------------CQPSGGILSCVNKDPC------------HGVTC-------------- 2851
C+ LS + PC HG C
Sbjct: 894 DLHTDLELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKE 953
Query: 2852 --------RPQETCKEQGGQGVC-LPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLAT 2902
P TC Q G C L +TC +GD HY +FDG FDF G C L
Sbjct: 954 YFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHL-- 1011
Query: 2903 TGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
V + F+V +N N + + + +++ +G ++ + D+ G
Sbjct: 1012 -----VKSTSDVSFSVIVENVNCYSSGMICRKFISI-NVGNSLIVFDDDSG--------N 1057
Query: 2963 ALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNM 3019
P S D + V + F + + +D V V + G + GLCGN
Sbjct: 1058 PSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNF 1117
Query: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC---PTCPEDRLEQYEGP 3076
D N+ P + +G SW A EC + C + L +
Sbjct: 1118 DLKTINEMRTPENLELTNPQEFGSSWAAV--------ECPDTLDPRDMCVLNPLREPFAK 1169
Query: 3077 GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKALASYVAACQAA 3134
C L F CH V F+ C+ D C GGD + C ++++Y C
Sbjct: 1170 KECSILLSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQH 1226
Query: 3135 GVVIEDWRAQVGCEITC 3151
GV + DWR C C
Sbjct: 1227 GVAV-DWRTPRLCPYDC 1242
Score = 298 bits (762), Expect = 1e-79
Identities = 305/1174 (25%), Positives = 450/1174 (38%), Gaps = 197/1174 (16%)
Query: 4069 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 4127
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 4128 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA 4187
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 4188 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 4247
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 4248 --APGWDPLCWDECRGSCPTCPEDRLEQYEGP--GFCGPLSSGTGGPFTTCHAHVPPESF 4303
AP P S P P L+Q G G + PF CHA+V P F
Sbjct: 315 EQAPNQPP---GPTTSSLPRPP--CLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPF 369
Query: 4304 FKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVC 4361
C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C
Sbjct: 370 TASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNEC 429
Query: 4362 GPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
CPASC P + E CV+GC C G + CV C C +GT + G
Sbjct: 430 IACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPG 485
Query: 4422 SEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPH 4481
S D C+ C C G C+ A C AEC GD H
Sbjct: 486 SVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVTGDIH 520
Query: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY- 4539
+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++ ++
Sbjct: 521 FTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQ 575
Query: 4540 --NHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF- 4596
+TL+ L D + P+ D+ LS + V T G+ + +D +
Sbjct: 576 DPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLR 634
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSK 4648
+ L+V + GLCG +N + DD + G P W+ A C VS
Sbjct: 635 LYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSG 692
Query: 4649 PCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGL 4708
PC Q + AC V+ T APC + P YF+ C DAC+ G P L
Sbjct: 693 SPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CL 748
Query: 4709 CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGC--- 4765
C +A Y C+ G + R C L C A Y C C +C L++PE C
Sbjct: 749 CATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVD 808
Query: 4766 ------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPG------- 4810
C EGC C D D CVP QC C G YP G+ P
Sbjct: 809 GGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCK 868
Query: 4811 ---PECERRCECG--PGGHV-----------------TCQE------------------- 4829
C+ R P G V TC++
Sbjct: 869 DGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGCAC 928
Query: 4830 -------GAACGPHEECRL----------EDGVQACHATGCGR-------------CLAN 4859
G AC EEC + + CH C R C A
Sbjct: 929 PQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAY 988
Query: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEK---NAAGDLQRLLVTVAG 4916
G HY T DG +D G+C L + D FS+++E ++G + R
Sbjct: 989 GDRHYRTFDGLPFDFVGACKVHLVK----STSDVSFSVIVENVNCYSSGMICR------- 1037
Query: 4917 QVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGR-------NMVLQTTKGLRLLFDGDAH 4969
+ +S+ G + V + P + E +V + + LL+D
Sbjct: 1038 KFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTT 1097
Query: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029
+ + ++G+L GLCGNF+ ++ P ++ + FG++W A C +
Sbjct: 1098 VHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAA----VECPDTLD 1153
Query: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDL--CAQKGDK 5087
P+ +C+ + + C L + F C V+ + ++ C+ D C+Q GD
Sbjct: 1154 PR--DMCVLNPLREPFAKKECSILLSE--VFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHC 5121
C S++AY C GVAV WRT CP C
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 280 bits (716), Expect = 3e-74
Identities = 247/825 (29%), Positives = 336/825 (40%), Gaps = 105/825 (12%)
Query: 450 AAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLP 509
A G RCQ+V E ++CRA G H TFDG Y + G SYT+V +
Sbjct: 132 ATGPRCQMVYNAG---PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQ-- 186
Query: 510 AFSVEAKNE-------HRGSRRVS--YVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLP 560
+FS++ N+ + SR VS +VG + + +T G R +LP
Sbjct: 187 SFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHL---AKEVTHG--------GMRVQLP 235
Query: 561 VSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPAD 620
+ RL+ Q +V + +D + + + GLCGN N DP D
Sbjct: 236 HVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKD 293
Query: 621 DFLTPDGALAPDAVEFASSWKLDDGDY--------LCEDGCQNNCPACTPGQAQHYEGDR 672
D +T G L D VEF SW+ + L C P G + E
Sbjct: 294 DLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEA-- 351
Query: 673 LCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISV 732
L PF CH + P PF C DLC G+ + CR L+ YA+AC + G +
Sbjct: 352 ------LLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 733 GDWRSP-ANCPLSCPANS-RYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG 790
WR+ C + C + Y C CP SC+ A+ + S CV+GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVD-SEIACVDGCYCPNGLIFED 464
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G CV + C C F G PG V D C CTC + + CPA CSV
Sbjct: 465 GGCVAPAECPCEFHGTLYPPGSVVKED--C-NTCTCTSGKWECS---TAVCPA--ECSV- 515
Query: 851 NGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENE 910
+GD H+ +FDGRR+ F TC Y+L S F V ++N
Sbjct: 516 ----------------TGDIHFTTFDGRRYTFPATCQYILAKSRSSG----TFTVTLQNA 555
Query: 911 HRG-SQTVSYTRAVRVEA-RGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD 968
G +Q + ++V V + + V G VL+ D + +P D ++ R
Sbjct: 556 PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIP-PYTDDAFEIRRLSSV 614
Query: 969 AV-VRTDFGLTVTYDWNA-RVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL 1026
+ VRT+ G+ V YD R+ +V + E GLCG FNG+ DD G +
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674
Query: 1027 AFGNSWQEETRPGCGATEPGD-CPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQ 1085
FGNSW +T C G D + S C +L F C + L P
Sbjct: 675 LFGNSW--KTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEM--FAPCSAFLSPV 730
Query: 1086 GAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145
C D C GQ LC LA YA C+ G V C LSC Y C
Sbjct: 731 PYFEQCRRDACRC-GQP-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPC 788
Query: 1146 SYGCPLSCGDLPVPGGCG---------SECHEGCVC--DEGFALSGESCLPLASCGCVHQ 1194
C +C DL P CG EC EGC C D + C+P C C Q
Sbjct: 789 VAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQ 848
Query: 1195 GTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSG 1239
G +PPG + P G CHC++ G++SC+S + P AC P+G
Sbjct: 849 GVDYPPGDSDIPSLG---HCHCKD-GVMSCDSRA--PAAAC-PAG 886
Score = 254 bits (649), Expect = 2e-66
Identities = 233/821 (28%), Positives = 317/821 (38%), Gaps = 90/821 (10%)
Query: 4440 GGSLVCTPASCGLGEVCGLLPSGQ--HGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCE 4497
GG V PA C P Q + P + C+AWG H T DG + G
Sbjct: 116 GGECV-HPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGS 174
Query: 4498 YLLSAPCHGPPLGAENFTVTVANEHR-GSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD 4556
Y L H P ++F++ V N+ + GS + +R+V+L +++
Sbjct: 175 YTLVGR-HEPE--GQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQ---EIHLAKEVTHG 228
Query: 4557 GVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNY 4616
G+ V LP + S L+G V+V S +LA+DG S V +++ GLCGN
Sbjct: 229 GMRVQLPHVMGSARLQQLAGY-VIVRHQSAFTLAWDGASAVYIKMSPELLGWTHGLCGNN 287
Query: 4617 NQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCT------PEQQESFGGPDACGV 4670
N DP DDL GK V E P P T P Q++ G GV
Sbjct: 288 NADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQ--GV 345
Query: 4671 ISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQL 4726
+ L P CH V P + C D CQ G C A+A Y AC AG L
Sbjct: 346 YEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPL 405
Query: 4727 GEWRRP-DFCPLQCPAHSH-YELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGD 4784
WR C + C + Y C CP SC ++ E AC +GC C G +
Sbjct: 406 QGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDG 465
Query: 4785 TCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDG 4844
CV +C C G YP PG + C C G
Sbjct: 466 GCVAPAECPCEFHGTLYP------PGSVVKEDCNT-------------------CTCTSG 500
Query: 4845 VQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNA 4903
C C C G IH+ T DGR Y +C Y+LA+ F++ L+
Sbjct: 501 KWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAK----SRSSGTFTVTLQNAP 556
Query: 4904 AG---------DLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL 4954
G + +L + V+L Q V + + +P ++ L
Sbjct: 557 CGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFL 616
Query: 4955 Q--TTKGLRLLFDGDA-HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETF 5011
+ T G+R+L+D + L + + + GLCG FNGN DDF+ P G S+ + F
Sbjct: 617 RVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLF 676
Query: 5012 GAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSE 5071
G +W+ + G C V L + A Y S +AC L FA C A LSP
Sbjct: 677 GNSWKTLSACSPLVSGSPLDPCDVHL--QAASY-SVQACSVLTGEM--FAPCSAFLSPVP 731
Query: 5072 YFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICT 5131
YF QC D C + + LC +LA Y C+ G+ V C L C A YS C
Sbjct: 732 YFEQCRRDAC--RCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCV 789
Query: 5132 RTCQGSCAALSGLTGC---------TTRCFEGCEC-DDRFLLSQG-VCIPVQDCGCTHNG 5180
C +C L+ C C EGC C D +L +Q +C+P C C G
Sbjct: 790 APCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQG 849
Query: 5181 RYLPVNSSLLTSDCSERCSCSS---SSGLTCQAAGCPPGRV 5218
P S + S C C S AA CP G+V
Sbjct: 850 VDYPPGDSDIPS--LGHCHCKDGVMSCDSRAPAAACPAGQV 888
Score = 248 bits (634), Expect = 9e-65
Identities = 240/854 (28%), Positives = 339/854 (39%), Gaps = 115/854 (13%)
Query: 2831 CQPSGGILSCVNKDPC-HGVTCRPQETCKEQGGQGVCL-------PNYEATCWLWGDPHY 2882
C PS + SC N C H C C+ G P ++ C WG H
Sbjct: 105 CAPSY-LFSCFNGGECVHPAFC----DCRRFNATGPRCQMVYNAGPERDSICRAWGQHHV 159
Query: 2883 HSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-GNPAVSYVRVVTVAAL 2941
+FDG + G +Y L P + F++ N + G+ + R V++ +
Sbjct: 160 ETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCGSSPYTCSRAVSLFFV 214
Query: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVD 3001
G IH + +V G+ LP + R+ Q A ++ +++D V
Sbjct: 215 GEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRHQSAFTLAWDGASAVY 269
Query: 3002 VTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR--APGWDP------L 3053
+ + G GLCGN + +P +D V +G L + + SW+ AP P L
Sbjct: 270 IKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSL 329
Query: 3054 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMG 3113
C P + EQ E L P PF CHA+V P F C D+C
Sbjct: 330 PRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVSPLPFTASCTSDLCQS 380
Query: 3114 GGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH-YEVCGPPCPASCPSP 3171
GD C+ALA Y AC AG ++ WR Q+ C + C E + Y C CPASC
Sbjct: 381 MGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC--- 437
Query: 3172 APLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQ 3231
P + E CV+GC C G + CV C C +GT + GS D C+
Sbjct: 438 HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTLYPPGSVVKED--CNT 494
Query: 3232 WCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDF 3291
C C G C+ A C AEC GD H+ T DG R+ F
Sbjct: 495 -CTC--TSGKWECSTAVC--------------------PAECSVTGDIHFTTFDGRRYTF 531
Query: 3292 QGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIY---NHSLTLSAR 3347
TC+Y+L+ + FTVT+ N G +Q + +SV++ ++ +TL+
Sbjct: 532 PATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQA 586
Query: 3348 WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF-VRLRVPAAYAG 3406
L D + P+ D+ LS + V T G+ + +D + + L+V +
Sbjct: 587 GD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVE 645
Query: 3407 SLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGECVSKPCPSPCTPEQQ 3458
GLCG +N + DD + G P W+ A C VS PC Q
Sbjct: 646 DTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSPLVSGSPLDPCDVHLQ 703
Query: 3459 ESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAAC 3518
+ AC V+ T APC + P YF+ C DAC+ G P LC +A Y C
Sbjct: 704 AASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQP-CLCATLAHYAHLC 759
Query: 3519 QAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC---------ESACR 3569
+ G + R C C A Y C C +C L++PE C C
Sbjct: 760 RRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECV 819
Query: 3570 EGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCE 3627
EGC C D D CVP QC C YP G + P G C C++ G +SC+
Sbjct: 820 EGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG---HCHCKD-GVMSCD 875
Query: 3628 PSSCGPHETCRPSG 3641
S P C P+G
Sbjct: 876 --SRAPAAAC-PAG 886
Score = 248 bits (634), Expect = 9e-65
Identities = 229/809 (28%), Positives = 327/809 (40%), Gaps = 102/809 (12%)
Query: 1667 PNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNR-G 1725
P ++ C WG H +FDG + G +Y L P + F++ N + G
Sbjct: 145 PERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-----FSIQVHNDPQCG 199
Query: 1726 NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA 1785
+ + R V++ +G IH + +V G+ LP + R+ Q A ++
Sbjct: 200 SSPYTCSRAVSLFFVGEQ-EIHLAK--EVTHGGMRVQLPHVMGSARLQ--QLAGYVIVRH 254
Query: 1786 DFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
+++D V + + G GLCGN + +P +D V +G L + + SW+
Sbjct: 255 QSAFTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQ 314
Query: 1846 --APGWDP------LCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVP 1897
AP P L C P + EQ E L P PF CHA+V
Sbjct: 315 EQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEAL-----LRP----PFDACHAYVS 365
Query: 1898 PESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEITCPENSH- 1955
P F C D+C GD C+ALA Y AC AG ++ WR Q+ C + C E +
Sbjct: 366 PLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFT 425
Query: 1956 YEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTY 2015
Y C + CPASC P + E CV+GC C G + CV C C +GT
Sbjct: 426 YNECIACCPASC---HPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAE-CPCEFHGTL 481
Query: 2016 HEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAW 2075
+ GS D C+ C C G C+ A C AEC
Sbjct: 482 YPPGSVVKED--CNT-CTC--TSGKWECSTAVC--------------------PAECSVT 516
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTL 2134
GD H+ T DG R+ F TC+Y+L+ + FTVT+ N G +Q + +SV++
Sbjct: 517 GDIHFTTFDGRRYTFPATCQYILA-----KSRSSGTFTVTLQNAPCGLNQDGACVQSVSV 571
Query: 2135 QIY---NHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
++ +TL+ L D + P+ D+ LS + V T G+ + +D
Sbjct: 572 ILHQDPRRQVTLTQAGD-VLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDR 630
Query: 2192 DSF-VRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPA--------GWQVGGAQGCGE 2242
+ + L+V + GLCG +N + DD + G P W+ A C
Sbjct: 631 EGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA--CSP 688
Query: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
VS PC Q + AC V+ T APC + P YF+ C DAC+ G
Sbjct: 689 LVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPYFEQCRRDACRC-GQ 745
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEG 2362
P LC +A Y C+ G + R C C A Y C C +C L++PE
Sbjct: 746 P-CLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEA 804
Query: 2363 C---------ESACREGCVC--DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
C C EGC C D D CVP QC C YP G + P G
Sbjct: 805 CGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLG- 863
Query: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSG 2440
C C++ G +SC+ S P C P+G
Sbjct: 864 --HCHCKD-GVMSCD--SRAPAAAC-PAG 886
Score = 161 bits (408), Expect = 1e-38
Identities = 154/588 (26%), Positives = 227/588 (38%), Gaps = 47/588 (7%)
Query: 4816 RCECGPGGHVTCQEGAACGPHE--ECRLEDGV----QACHATGCGR---CLANGGIHYIT 4866
R +C P +C G C +CR + Q + G R C A G H T
Sbjct: 102 RAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVET 161
Query: 4867 LDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-------LVTVAGQVV 4919
DG Y L G SY L V +P + FSI + + L V Q +
Sbjct: 162 FDGLYYYLSGKGSYTL--VGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEI 219
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFR 4979
LA+ +VT G V LP +G R+ ++++ L +DG + + + +
Sbjct: 220 HLAK--EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGASAVYIKMSPELL 277
Query: 4980 GRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAE 5039
G GLCGN N + DD V +G V F +W+ ++ G P CL +
Sbjct: 278 GWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQ 337
Query: 5040 ETAPYES-NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYT 5098
+ E C L P PF C A +SP + C DLC GD A CR+LA Y
Sbjct: 338 NPGTMQGVYEQCEALLRP--PFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYA 395
Query: 5099 AACQAAGVAVKPWRTD-SFCPLHCPAHSH-YSICTRTCQGSCAALSGLTGCTTRCFEGCE 5156
AC AG ++ WRT C +HC + Y+ C C SC + C +GC
Sbjct: 396 RACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCY 455
Query: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
C + + G C+ +C C +G P S++ DC+ C+C+S C A CP
Sbjct: 456 CPNGLIFEDGGCVAPAECPCEFHGTLYP-PGSVVKEDCN-TCTCTSGK-WECSTAVCP-- 510
Query: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYR 5276
AE C ++ + TTFDG R + Y L+ T+
Sbjct: 511 ------AE----------CSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQN 554
Query: 5277 VVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDG 5336
+ ++V + VTLT V + +P + + R
Sbjct: 555 APCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSV 614
Query: 5337 SLLVRQKAGVQVWLGANG-KVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
L VR GV+V G ++ + V G CG F+G+ +D+
Sbjct: 615 FLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDF 662
Score = 115 bits (287), Expect = 2e-24
Identities = 111/421 (26%), Positives = 162/421 (38%), Gaps = 61/421 (14%)
Query: 729 GISVGDWRSPANCPLSCPANSRYELCGP-------ACPTSCNGAAAPSNCSGR-PCVEGC 780
G+ D R+PA +CPA + C + +C + S R PC+ GC
Sbjct: 870 GVMSCDSRAPA---AACPAGQVFVNCSDLHTDLELSRERTCEQQLLNLSVSARGPCLSGC 926
Query: 781 VCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQS 840
C G + G AC C CT++G + PG +V + C C C + Q T S
Sbjct: 927 ACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSP--C-HTCVCQRGSFQCTLHPCAS 983
Query: 841 CPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
TC GD HY +FDG FDF+G C LV S
Sbjct: 984 ----------------------TCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD---- 1017
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG-- 958
+F V+VEN + S + + + + + V DD P D
Sbjct: 1018 VSFSVIVENVNCYSSGMICRKFISINVGNSLI---------VFDDDSGNPSPESFLDDKQ 1068
Query: 959 QVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALR 1017
+V +R G +V +T+ +D V + + L GLCGNF+ +++
Sbjct: 1069 EVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTP 1128
Query: 1018 GGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
+ N FG+SW P +P D L+ L ++ +K EC IL F
Sbjct: 1129 ENLELTNPQEFGSSWAAVECP--DTLDPRDMCVLNPL--REPFAKKECSILLSE--VFEI 1182
Query: 1078 CHSKLDPQGAVRDCVYDR--CLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS 1135
CH +D +C+ D C G C +++ YA C G V WR+ LCP
Sbjct: 1183 CHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYD 1241
Query: 1136 C 1136
C
Sbjct: 1242 C 1242
Score = 98.6 bits (244), Expect = 1e-19
Identities = 82/297 (27%), Positives = 126/297 (42%), Gaps = 27/297 (9%)
Query: 455 CQVVGGKAGCVAESTA-VCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSV 513
C G C A C A GD HY TFDG +D +G C +V+ S+ +FSV
Sbjct: 967 CVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD----VSFSV 1022
Query: 514 EAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS 573
+N + Y + R + +S+ G V D+ + P S + + V+
Sbjct: 1023 IVENVN------CYSSGMICRKF---ISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTW 1073
Query: 574 GPRAVVELVFGLV-VTYDWDCQLALSLPA--RFQDQVCGLCGNYNGDPADDFLTPDGALA 630
+ F +T WD + + + A ++Q Q+ GLCGN++ ++ TP+
Sbjct: 1074 RVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLEL 1133
Query: 631 PDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDT 690
+ EF SSW + C D C + + C +L L F +CH
Sbjct: 1134 TNPQEFGSSWAAVE----CPDTLDPR-DMCVLNPLREPFAKKECSIL--LSEVFEICHPV 1186
Query: 691 LDPRPFLEQCVYDL--CVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC 745
+D F C+ D C GG+ C +SAYA C + G++V DWR+P CP C
Sbjct: 1187 VDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-DWRTPRLCPYDC 1242
Score = 92.4 bits (228), Expect = 1e-17
Identities = 117/502 (23%), Positives = 189/502 (37%), Gaps = 87/502 (17%)
Query: 4755 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH----DGRYYPLGEVFYPG 4810
S P+LS EG A + + TCVP+ + C+ +G+ + + +
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHICLEGQLIRVNQSQHC- 2078
Query: 4811 PECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGR 4870
P+ CG G G C P EC AC RC + ++T DG
Sbjct: 2079 PQGAAPPRCGILGLAVRVGGDRCCPLWEC-------AC------RCSIFPDLSFVTFDGS 2125
Query: 4871 VYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRL-----------LVTVAGQVV 4919
L Y+L+Q DE ++ + + +L L + +A QV
Sbjct: 2126 HVALFKEAIYILSQ-----SPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVT 2180
Query: 4920 SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLM---SIPS 4976
++VTVD + V PV+ R+ G ++ T +++ + + L++ S S
Sbjct: 2181 IDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS 2240
Query: 4977 PFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET---FGAAWRAPGSSKGCGE------G 5027
+G GLCG +G+ ++D L +GS E F +W+ P S G+
Sbjct: 2241 KAQGH--GLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDS 2298
Query: 5028 CGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087
C C CL + AC + P+ + C+ + ++Y +Q
Sbjct: 2299 CATTDCSPCL--RMVSNRTFSACHRFVPPE---SFCELWIRDTKYVQQP----------- 2342
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTG- 5146
C +L Y A C V ++ WR +CP C + S Y C C+ G+ G
Sbjct: 2343 ---CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGP 2398
Query: 5147 -----CTTRCFEGCECDDRFLLSQ---GVCIPVQDCGCTHN---GRYLPVNSSLLTSDCS 5195
C EGC C + +L + +CIP C CT + R L + S C
Sbjct: 2399 LDPEHCQV-LGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCC 2457
Query: 5196 ERCSCSSSSGLTCQAAGCPPGR 5217
+ C + + GCP R
Sbjct: 2458 QH-QCQAPDTIVPVDLGCPSPR 2478
Score = 91.3 bits (225), Expect = 2e-17
Identities = 115/456 (25%), Positives = 171/456 (37%), Gaps = 78/456 (17%)
Query: 419 GLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQ-----------------RCQV---- 457
GLA+A+ T A+ T + E C C GQ RC +
Sbjct: 2034 GLAEALATTTEANTSTTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLA 2093
Query: 458 --VGGKAGC-VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVE 514
VGG C + E C D + TFDG + Y + + S D+ L ++
Sbjct: 2094 VRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQ--SPDEMLTVHVLD 2151
Query: 515 AKNEHRGSRRVSYVGLVTVRA--YSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
K+ + G LV + +H V++ R V VD Q PVS R+
Sbjct: 2152 CKSANLGHLNWPPFCLVMLNMTHLAHQVTIDRFNRK-VTVDLQPVWPPVS--RYGFRIED 2208
Query: 573 SGPRAVVELVFGLVVTYDWDCQLALSLPARFQD-QVCGLCGNYNGDPADDFLTPDGAL-- 629
+G ++ + + + L + ++ Q GLCG +GD A+D DG++
Sbjct: 2209 TGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVG 2268
Query: 630 -APDAVEFASSWKLDDG------DYLCEDGCQN-NCPACTPGQAQHYEGDRLCGMLTKLD 681
A D F SW++ D C +C C R+ T
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCL----------RMVSNRT--- 2315
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANC 741
F+ CH + P F E + D V C L+ Y C + + + +WR C
Sbjct: 2316 --FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRSDYC 2368
Query: 742 PLSCPANSRYELCGPAC--PTSCN----GAAAPSNCSGRPCVEGCVCLPGFV---ASGGA 792
P C ++S Y+ C AC P +C G P +C + EGCVC G +
Sbjct: 2369 PFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHC--QVLGEGCVCSEGTILHRRHSAL 2426
Query: 793 CVPASSCGCT-FQGLQLAPGQEVWADEL---CQRRC 824
C+P + C CT G+ A G E W L CQ +C
Sbjct: 2427 CIPEAKCACTDSMGVPRALG-ETWNSSLSGCCQHQC 2461
Score = 90.1 bits (222), Expect = 5e-17
Identities = 121/509 (23%), Positives = 184/509 (36%), Gaps = 82/509 (16%)
Query: 1216 CQEGGLVSCESSSCGPHEACQPSGGSLG---------CVAVGSSTCQAS--GDPHYTTFD 1264
C EG L+ S P A P G LG C + C+ S D + TFD
Sbjct: 2064 CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFD 2123
Query: 1265 GRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQ 1324
G +Y+L+Q+ +H N+ N ++ + + +++
Sbjct: 2124 GSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQVTIDR 2183
Query: 1325 RQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQ 1384
KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2184 FNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASKTSKA 2242
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPTPCPPGSEDC 1441
Q GLCG +GD +D +GS G A + F +SW+ VP S L D
Sbjct: 2243 QGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSS--LTSVGQTRFRPDS 2298
Query: 1442 IPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 1501
+ C P L ++S+ T S+CH+ V P+ + I D +
Sbjct: 2299 CATTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY----VQQP 2342
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDG 1561
C + YV+ C +E WR +CP C +S Y+ C C P CQDG
Sbjct: 2343 CVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPKTCQDG 2394
Query: 1562 ------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPEQTVLI 1602
EGC C G + + C+P +C C + GV E + L
Sbjct: 2395 ILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLS 2454
Query: 1603 DNCRQQCTCHAGKGMVCQEHSC---KPGQVCQPSGGILSCVTKDP-------------CH 1646
C+ Q C A +V + C +P + L TKDP C
Sbjct: 2455 GCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCE 2512
Query: 1647 GV--TCRPQETCKEQGGQGVCLPNYEATC 1673
G+ TCRP + C P+Y C
Sbjct: 2513 GLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 86.3 bits (212), Expect = 8e-16
Identities = 87/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 3182 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 3240
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 920 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 972
Query: 3241 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLS 3300
S CT C + C A+GD HY T DG FDF G C+ L
Sbjct: 973 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012
Query: 3301 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 3360
+F+V V N + S + + +++ + N + D +
Sbjct: 1013 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 1059
Query: 3361 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 3417
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 3418 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 3469
++++ P ++ Q G + CP P +E F + +
Sbjct: 1120 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1175
Query: 3470 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 3527
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1176 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1231
Query: 3528 WRRPDFCPFQC 3538
WR P CP+ C
Sbjct: 1232 WRTPRLCPYDC 1242
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 2045 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAP 2101
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 2102 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 2146
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 2147 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 2201
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 2202 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 2260
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 2261 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 2313
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 2314 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 2367
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 2368 REGCVCDAGFVL---SGDTCVPVGQCGC 2392
EGCVC G +L C+P +C C
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 85.9 bits (211), Expect = 1e-15
Identities = 100/388 (25%), Positives = 148/388 (38%), Gaps = 76/388 (19%)
Query: 3246 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 3302
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 3303 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 3347
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 3348 -WPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 3402
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 3403 AYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 3461
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 3462 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 3514
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 3515 VAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSC--PGSCP----SLSAPEGCESAC 3568
VA C + EWRR D+CPF C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 3569 REGCVCDAGFVL---SGDTCVPVGQCGC 3593
EGCVC G +L C+P +C C
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCAC 2435
Score = 84.7 bits (208), Expect = 2e-15
Identities = 105/415 (25%), Positives = 157/415 (37%), Gaps = 79/415 (19%)
Query: 4447 PASCGLGEVCGL-LPSGQHGCQPV--STAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAP 4503
P CG + GL + G C P+ C + D +VT DG Y+LS
Sbjct: 2084 PPRCG---ILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS 2140
Query: 4504 -----------CHGPPLGAEN---FTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSAR- 4548
C LG N F + + N VT+ +N +T+ +
Sbjct: 2141 PDEMLTVHVLDCKSANLGHLNWPPFCLVMLN------MTHLAHQVTIDRFNRKVTVDLQP 2194
Query: 4549 -WPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRL----RVPA 4603
WP + F+++ H ++ + T S + + + S + + +
Sbjct: 2195 VWPPVSRYG-------FRIEDTGHMYM------ILTPSDIQIQWLHSSGLMIVEASKTSK 2241
Query: 4604 AYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECV-SKPCPSPCTPEQQESF 4662
A LCG+C D A+DL G VGGA+ + S PS T Q F
Sbjct: 2242 AQGHGLCGICDG---DAANDLTLKDGSV----VGGAEDPAPFLDSWQVPSSLTSVGQTRF 2294
Query: 4663 GGPDACGVISAT-------DGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
PD+C + + + CH VPP + + + D VQ C A+ Y
Sbjct: 2295 R-PDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVY 2349
Query: 4716 VAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSC--PVSCP----SLSAPEGCESAC 4769
VA C + EWRR D+CP C + S Y+ C +C P +C PE C+
Sbjct: 2350 VAMCHKFHVCI-EWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQ-VL 2407
Query: 4770 REGCVCDAGFVL---SGDTCVPVGQCGCLHD-GRYYPLGEVFYPGPE--CERRCE 4818
EGCVC G +L C+P +C C G LGE + C+ +C+
Sbjct: 2408 GEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQ 2462
Score = 84.3 bits (207), Expect = 3e-15
Identities = 86/371 (23%), Positives = 133/371 (35%), Gaps = 62/371 (16%)
Query: 1981 GPCVEGCQCDAGFVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGG 2039
GPC+ GC C G + D C L C C W Y F D S C G
Sbjct: 920 GPCLSGCACPQGLLRHGDACF-LPEECPCTWKGKEY------FPGDQVMSPCHTCVCQRG 972
Query: 2040 SLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLS 2099
S CT C + C A+GD HY T DG F+F G C+ L
Sbjct: 973 SFQCTLHPCA--------------------STCTAYGDRHYRTFDGLPFDFVGACKVHLV 1012
Query: 2100 APCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVT 2159
+F+V V N + S + + +++ + N + D +
Sbjct: 1013 -----KSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDD--------DSGNPS 1059
Query: 2160 LPFQLDSLLHAH---LSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQ 2216
LD H + +V ++L +D + V ++ + G L GLCGN++
Sbjct: 1060 PESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDL 1119
Query: 2217 DPADDLKAVGGKPAGWQVGGAQGCGEC-VSKPCPSPCTPEQ-------QESFGGPDACGV 2268
++++ P ++ Q G + CP P +E F + +
Sbjct: 1120 KTINEMRT----PENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSIL 1175
Query: 2269 ISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLRE 2326
+S CH +V ++ CL D C G C +V+ Y C G + +
Sbjct: 1176 LSEV---FEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAV-D 1231
Query: 2327 WRRPDFCPFQC 2337
WR P CP+ C
Sbjct: 1232 WRTPRLCPYDC 1242
Score = 83.6 bits (205), Expect = 5e-15
Identities = 131/574 (22%), Positives = 200/574 (34%), Gaps = 109/574 (18%)
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 3613
S P+LS EG A + + TCVP+ + C+
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 2063
Query: 3614 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 3662
C EG + S P P G LG C + C+ S D +
Sbjct: 2064 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2119
Query: 3663 TTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2120 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2179
Query: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2180 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2238
Query: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPCLPPPT-CPP 3838
GLCG +GD +D +GS G A + F +SW+ VP S T P
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2296
Query: 3839 GSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
S C +D C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2297 DS--CATTD-CSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDTKY--- 2338
Query: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPL 3958
+ C + YV+ C +E WR +CP C +S Y+ C C P
Sbjct: 2339 -VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC-------EPPK 2389
Query: 3959 QCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN-GV---YYEPE 3999
C DG EGC C G + + C+P +C C + GV E
Sbjct: 2390 TCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETW 2449
Query: 4000 QTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVTKDP---------- 4046
+ L C+ Q C +V + C +P + L TKDP
Sbjct: 2450 NSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCN 2507
Query: 4047 ---CHGV--TCRPQETCKEQGGQGVCLPNYEATC 4075
C G+ TCRP + C P+Y C
Sbjct: 2508 QTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 82.0 bits (201), Expect = 1e-14
Identities = 126/579 (21%), Positives = 197/579 (34%), Gaps = 119/579 (20%)
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCD 2412
S P+LS EG A + + TCVP+ + C+
Sbjct: 2025 SAPALSIVEGLAEALATTTEAN-----TSTTCVPIAEQDCVRHI---------------- 2063
Query: 2413 SLCRCREGGEVSCEPSSCGPHETCRPSGGSLG---------CVAVGSTTCQAS--GDPHY 2461
C EG + S P P G LG C + C+ S D +
Sbjct: 2064 ----CLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSF 2119
Query: 2462 TTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521
TFDG +Y+L+Q+ +H N+ N ++ + +
Sbjct: 2120 VTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLVMLNMTHLAHQV 2179
Query: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581
+++ KVTV+ + PV +I + H ++ +D ++ + + V
Sbjct: 2180 TIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMI-VEASK 2238
Query: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE---FGNSWEEVVPDSPC------LPP 2632
GLCG +GD +D +GS G A + F +SW+ VP S P
Sbjct: 2239 TSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQ--VPSSLTSVGQTRFRP 2296
Query: 2633 PTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL 2692
+C + +C P L ++S+ T S+CH+ V P+ + I D
Sbjct: 2297 DSCA--------TTDCSPCLR----------MVSNRT--FSACHRFVPPESFCELWIRDT 2336
Query: 2693 CLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA 2752
+ C + YV+ C +E WR +CP C +S Y+ C C
Sbjct: 2337 KY----VQQPCVALTVYVAMCHKFHVCIE-WRRSDYCPFLCSSDSTYQACVTAC------ 2385
Query: 2753 LSAPLQCPDG------------CAEGCQCDSGFLY---NGQACVPIQQCGCYHN----GA 2793
P C DG EGC C G + + C+P +C C + A
Sbjct: 2386 -EPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRA 2444
Query: 2794 YYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC---KPGQVCQPSGGILSCVNKDP----- 2845
E + L C+ Q C +V + C +P + L KDP
Sbjct: 2445 LGETWNSSLSGCCQHQ--CQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGT 2502
Query: 2846 --------CHGV--TCRPQETCKEQGGQGVCLPNYEATC 2874
C G+ TCRP + C P+Y C
Sbjct: 2503 VCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCEC 2541
Score = 78.6 bits (192), Expect = 2e-13
Identities = 119/493 (24%), Positives = 165/493 (33%), Gaps = 111/493 (22%)
Query: 816 ADELCQRRCTCNGATHQVTCRDKQSCPAGE---RCSVQNGLLG---------CYPDRFGT 863
A++ C R G +V Q CP G RC G+LG C P
Sbjct: 2055 AEQDCVRHICLEGQLIRVN--QSQHCPQGAAPPRC----GILGLAVRVGGDRCCPLWECA 2108
Query: 864 CQGS--GDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL----------------PAFRV 905
C+ S D +V+FDG Y+L S + + P V
Sbjct: 2109 CRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSANLGHLNWPPFCLV 2168
Query: 906 LVENEHRGSQTV--SYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVF 963
++ H Q + R V V+ + V V R G + D Y+ +D Q+Q
Sbjct: 2169 MLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRY--GFRIEDTGHMYMILTPSDIQIQWL 2226
Query: 964 RQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGG---G 1020
+V +K + LCG+C +GD A+DL L+ G G
Sbjct: 2227 HSSGLMIVEA---------------SKTSKAQGHGLCGIC---DGDAANDLTLKDGSVVG 2268
Query: 1021 QAANALAFGNSWQEE---TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRE 1077
A + F +SWQ T G P C D ++ S F
Sbjct: 2269 GAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRT----------FSA 2318
Query: 1078 CHSKLDPQGA----VRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCP 1133
CH + P+ +RD Y + C AL Y A C + WR + CP
Sbjct: 2319 CHRFVPPESFCELWIRDTKYVQ--------QPCVALTVYVAMCHKFHVCIE-WRRSDYCP 2369
Query: 1134 LSCPPHSHYEACSYGC--PLSCGDLPVPGGCGSECH---EGCVCDEGFAL---SGESCLP 1185
C S Y+AC C P +C D + C EGCVC EG L C+P
Sbjct: 2370 FLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIP 2429
Query: 1186 LASCGCV-HQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGC 1244
A C C G G+T+ L C C + P LGC
Sbjct: 2430 EAKCACTDSMGVPRALGETW-------------NSSLSGCCQHQCQAPDTIVPV--DLGC 2474
Query: 1245 VAVGSSTCQASGD 1257
+ +C G+
Sbjct: 2475 PSPRPESCLRFGE 2487
Score = 67.0 bits (162), Expect = 5e-10
Identities = 126/501 (25%), Positives = 178/501 (35%), Gaps = 85/501 (16%)
Query: 2800 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQET 2856
T + Q C H+ G+++ + P P GIL G+ R
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGIL---------GLAVRV--- 2096
Query: 2857 CKEQGGQGVCLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLT 2914
G C P +E C ++ D + +FDG Y+L+ + + LT
Sbjct: 2097 -----GGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLT 2146
Query: 2915 PFTVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADG 2971
+ K+ N G+ P V ++ + L ++I + KV V+ PVS
Sbjct: 2147 VHVLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGF 2204
Query: 2972 RISVTQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFP 3030
RI T L +D +Q + V+ + S G GLCG D + ND
Sbjct: 2205 RIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLK 2262
Query: 3031 NGTL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCG 3080
+G++ AP + W S + G D C + C C
Sbjct: 2263 DGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC--------------- 2307
Query: 3081 PLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIED 3140
L + F+ CH VPPESF + + D C AL YVA C V IE
Sbjct: 2308 -LRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE- 2361
Query: 3141 WRAQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL 3196
WR C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2362 WRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTIL 2419
Query: 3197 ---SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCT 3245
+ C+P C C + A E W G C C+ G
Sbjct: 2420 HRRHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPR 2478
Query: 3246 PASC-GLGEVCGLLPSGQHGC 3265
P SC GEV LLP+ C
Sbjct: 2479 PESCLRFGEVALLLPTKDPCC 2499
Score = 67.0 bits (162), Expect = 5e-10
Identities = 113/432 (26%), Positives = 159/432 (36%), Gaps = 65/432 (15%)
Query: 1665 CLPNYEATCW--LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQ 1722
C P +E C ++ D + +FDG Y+L+ + + LT + K+
Sbjct: 2101 CCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVHVLDCKSA 2155
Query: 1723 NRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGAS 1779
N G+ P V ++ + L ++I + KV V+ PVS RI T
Sbjct: 2156 NLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRIEDTGHMY 2213
Query: 1780 KALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTL----- 1833
L +D +Q + V+ + S G GLCG D + ND +G++
Sbjct: 2214 MILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDGSVVGGAE 2271
Query: 1834 --APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPLAPGTGGP 1888
AP + W S + G D C + C C L +
Sbjct: 2272 DPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------LRMVSNRT 2315
Query: 1889 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI 1948
F+ CH VPPESF + + D C AL YVA C V IE WR C
Sbjct: 2316 FSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WRRSDYCPF 2370
Query: 1949 TCPENSHYEVCGSPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL---SADRCV 2001
C +S Y+ C + C P +C PL P C+ EGC C G +L + C+
Sbjct: 2371 LCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHRRHSALCI 2428
Query: 2002 PLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPASC-GLGE 2052
P C C + A E W G C C+ G P SC GE
Sbjct: 2429 P-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGE 2487
Query: 2053 VCGLLPSGQHGC 2064
V LLP+ C
Sbjct: 2488 VALLLPTKDPCC 2499
Score = 65.9 bits (159), Expect = 1e-09
Identities = 123/499 (24%), Positives = 174/499 (34%), Gaps = 81/499 (16%)
Query: 4001 TVLIDNCRQQCTCHV---GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQET 4057
T + Q C H+ G+++ + P P GIL + G C P
Sbjct: 2049 TTCVPIAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVR--VGGDRCCPLWE 2106
Query: 4058 CKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPF 4117
C C ++ D + +FDG Y+L+ + + LT
Sbjct: 2107 CA-------------CRCSIFPDLSFVTFDGSHVALFKEAIYILSQS-----PDEMLTVH 2148
Query: 4118 TVTTKNQNRGN---PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRI 4174
+ K+ N G+ P V ++ + L ++I + KV V+ PVS RI
Sbjct: 2149 VLDCKSANLGHLNWPPFCLV-MLNMTHLAHQVTIDRFN-RKVTVDLQPVWPPVSRYGFRI 2206
Query: 4175 SVAQGASKALLVADFGLQVSYDWNWR-VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNG 4233
L +D +Q + V+ + S G GLCG D + ND +G
Sbjct: 2207 EDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGH--GLCGICDGDAANDLTLKDG 2264
Query: 4234 TL-------APSIPIWG--GSWRAPGWDPLCWDECRGS-CPTCPEDRLEQYEGPGFCGPL 4283
++ AP + W S + G D C + C C L
Sbjct: 2265 SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPC----------------L 2308
Query: 4284 SSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWR 4343
+ F+ CH VPPESF + + D C AL YVA C V IE WR
Sbjct: 2309 RMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCIE-WR 2363
Query: 4344 AQVGCEITCPENSHYEVCGPPC--PASCPSP--APLTTPAVCEGPCVEGCQCDAGFVL-- 4397
C C +S Y+ C C P +C PL P C+ EGC C G +L
Sbjct: 2364 RSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPL-DPEHCQ-VLGEGCVCSEGTILHR 2421
Query: 4398 -SADRCVPLNNGCGCWANGTYHEAGSEFW---ADGTCSQWCRCGP-----GGGSLVCTPA 4448
+ C+P C C + A E W G C C+ G P
Sbjct: 2422 RHSALCIP-EAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPE 2480
Query: 4449 SC-GLGEVCGLLPSGQHGC 4466
SC GEV LLP+ C
Sbjct: 2481 SCLRFGEVALLLPTKDPCC 2499
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 244 bits (622), Expect = 2e-63
Identities = 255/1031 (24%), Positives = 400/1031 (38%), Gaps = 156/1031 (15%)
Query: 1091 CVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--LCPLS-CPPHSHYEACS 1146
C+ + C ++ CD + + C + G T WRS+ +C CP Y+ C
Sbjct: 714 CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 772
Query: 1147 YGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GES--CLPLASCGCVHQGTYHPPGQ 1202
P +C + V SEC GC C EG+ L GE C+ A C C GT + PG+
Sbjct: 773 PSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 1203 TFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTT 1262
GP C S C CQ+ SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL------------------TT 867
Query: 1263 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1322
FDG +++F G C ++ +++ E +G+ + N ++ +
Sbjct: 868 FDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920
Query: 1323 EQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VT 1377
++ + TV ++ + +I+ S + +ET F +++ +V ++ V+
Sbjct: 921 DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 980
Query: 1378 VPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPG 1437
+P N + GLCG+YN +DDF + F NSWE + CP G
Sbjct: 981 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKG 1030
Query: 1438 S-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 1496
+ CI +EK+ E CG+L +GPL+SCH +V+P+ ++C C
Sbjct: 1031 NPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1083
Query: 1497 NLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP 1556
+ LC+ + YV AC ++ WRT C CP ++ C+ C +LS
Sbjct: 1084 SQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERD 1142
Query: 1557 Q---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDN----CR-- 1606
+ +D +GC C N + CV QC CY N +P + + ID+ CR
Sbjct: 1143 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 1607 ------------QQC--------------------TCHAGKGMVCQEH-SCKPGQVCQPS 1633
Q C TC V E+ CK G C P
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFC-PE 1261
Query: 1634 GGILS----CVTKDPC-----------HGVTCRPQETCKEQGGQGVCLPN-YEATCWLWG 1677
G + + CV + C VT C G C N + C ++G
Sbjct: 1262 GMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYG 1321
Query: 1678 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTV 1737
+ H +FDG+ + F G C Y C + F + T++ ++ R + V
Sbjct: 1322 EGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN----GTFRILTESVPCCEDGLTCSRKIIV 1377
Query: 1738 AALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNW 1797
A NI + + GKV + + S+ +L G+ V +D N
Sbjct: 1378 AFQDQNIVL---QDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNT 1434
Query: 1798 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 1857
R+ V L +++G VCGLCGN + + +D ++A +G SW+ C D
Sbjct: 1435 RLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTV 1491
Query: 1858 RGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1917
+ P C + + C L T F CH V P ++ C+ + C +
Sbjct: 1492 AQTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGK 1547
Query: 1918 IL--CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGSPCPASCP 1968
L C A+A Y AC A GV + WR C + C + HYE CG+ +C
Sbjct: 1548 YLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1606
Query: 1969 SP-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADG 2026
++ EG C C A ++ + +CV L+ C C+ N G +
Sbjct: 1607 DQLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IED 1661
Query: 2027 TCSQWCRCGPG 2037
C + C C G
Sbjct: 1662 NCGRTCYCIAG 1672
Score = 232 bits (591), Expect = 9e-60
Identities = 249/1030 (24%), Positives = 391/1030 (37%), Gaps = 154/1030 (14%)
Query: 2292 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCG 2347
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 772
Query: 2348 DSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDDRYYPLGQ 2403
S P +C +++ + +S C GC C G++L CV +C C Y G+
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 2404 TFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTT 2463
GP C S C C++ + SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDA-KWSCTEALCPGR--CKVEGSSL------------------TT 867
Query: 2464 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 2523
FDG +++F G C ++ +++ E +G+ + N ++ +
Sbjct: 868 FDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920
Query: 2524 EQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VT 2578
++ + TV ++ + +I+ S + +ET F +++ +V ++ V+
Sbjct: 921 DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 980
Query: 2579 VPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPG 2638
+P N + GLCG+YN +DDF + F NSWE + +CP G
Sbjct: 981 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKG 1030
Query: 2639 S-EGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 2697
+ CI +EK+ E CG+L +GPL+SCH +V+P+ ++C C
Sbjct: 1031 NPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1083
Query: 2698 NLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSA-- 2755
+ LC+ + YV AC + WR C CP ++ C+ C +LS
Sbjct: 1084 SQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERD 1142
Query: 2756 -PLQCPDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGAYYEPEQTVLIDN----CR-- 2807
D +GC C N + CV QC CY N +P + + ID+ CR
Sbjct: 1143 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 2808 ------------QQC--------------------TCHVGKVVVCQEH-SCKPGQVC--- 2831
Q C TC + V E+ CK G C
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEG 1262
Query: 2832 --QPSGGILSCVNKDPCH---------GVTCRPQETCKEQGGQGVCLPNY-EATCWLWGD 2879
+ S GI N PC VT C G C N + C ++G+
Sbjct: 1263 MVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGE 1322
Query: 2880 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 2939
H +FDG+ + F G C Y C + F + T++ ++ R + VA
Sbjct: 1323 GHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT----FRILTESVPCCEDGLTCSRKIIVA 1378
Query: 2940 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWR 2999
NI + GKV + + S+ +L G+ V +D N R
Sbjct: 1379 FQDQNIVLQD---GKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 1435
Query: 3000 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 3059
+ V L +++G VCGLCGN + + +D ++A +G SW+ C D
Sbjct: 1436 LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTVA 1492
Query: 3060 GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 3119
+ P C + + C L T F CH V P ++ C+ + C +
Sbjct: 1493 QTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGKY 1548
Query: 3120 L--CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPS 3170
L C A+A Y AC A GV + WR C + C + HYE CG +C
Sbjct: 1549 LGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1607
Query: 3171 P-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADGT 3228
++ EG C C A ++ + +CV L+ C C+ N G +
Sbjct: 1608 QLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IEDN 1662
Query: 3229 CSQWCRCGPG 3238
C + C C G
Sbjct: 1663 CGRTCYCIAG 1672
Score = 231 bits (590), Expect = 1e-59
Identities = 248/1031 (24%), Positives = 394/1031 (38%), Gaps = 156/1031 (15%)
Query: 3493 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCG 3548
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 772
Query: 3549 DSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDDRYYPLGQ 3604
S P +C +++ + +S C GC C G++L CV +C C Y G+
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 3605 TFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTT 3664
GP C S C C++ + SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDA-KWSCTEALCPGR--CKVEGSSL------------------TT 867
Query: 3665 FDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 3724
FDG +++F G C ++ +++ E +G+ + N ++ +
Sbjct: 868 FDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920
Query: 3725 EQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VT 3779
++ + TV ++ + +I+ S + +ET F +++ +V ++ V+
Sbjct: 921 DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 980
Query: 3780 VPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPG 3839
+P N + GLCG+YN +DDF + F NSWE + +CP G
Sbjct: 981 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKG 1030
Query: 3840 S-AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
+ + CI +EK+ E CG+L +GPL+SCH +V+P+ ++C C
Sbjct: 1031 NPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1083
Query: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSA-- 3956
+ LC+ + YV AC ++ WR C CP ++ C+ C +LS
Sbjct: 1084 SQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERD 1142
Query: 3957 -PLQCPDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDN----CR-- 4008
D +GC C N + CV QC CY N +P + + ID+ CR
Sbjct: 1143 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 4009 ------------QQC--------------------TCHVGKVVVCQEH-SCKPGQVCQPS 4035
Q C TC + V E+ CK G C P
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFC-PE 1261
Query: 4036 GGILS----CVTKDPCH-----------GVTCRPQETCKEQGGQGVCLPNY-EATCWLWG 4079
G + + CV + C VT C G C N + C ++G
Sbjct: 1262 GMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYG 1321
Query: 4080 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTV 4139
+ H +FDG+ + F G C Y C + F + T++ ++ R + V
Sbjct: 1322 EGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT----FRILTESVPCCEDGLTCSRKIIV 1377
Query: 4140 AALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNW 4199
A NI + GKV + + S+ +L G+ V +D N
Sbjct: 1378 AFQDQNIVLQD---GKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNT 1434
Query: 4200 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 4259
R+ V L +++G VCGLCGN + + +D ++A +G SW+ C D
Sbjct: 1435 RLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTV 1491
Query: 4260 RGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 4319
+ P C + + C L T F CH V P ++ C+ + C +
Sbjct: 1492 AQTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGK 1547
Query: 4320 IL--CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCP 4370
L C A+A Y AC A GV + WR C + C + HYE CG +C
Sbjct: 1548 YLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1606
Query: 4371 SP-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
++ EG C C A ++ + +CV L+ C C+ N G +
Sbjct: 1607 DQLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IED 1661
Query: 4429 TCSQWCRCGPG 4439
C + C C G
Sbjct: 1662 NCGRTCYCIAG 1672
Score = 221 bits (563), Expect = 2e-56
Identities = 224/883 (25%), Positives = 339/883 (38%), Gaps = 146/883 (16%)
Query: 452 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 510
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 893
Query: 511 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566
+ G+ S L V V Y + T V N + R
Sbjct: 894 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 945
Query: 567 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 946 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 1005
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 1006 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1057
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEH 1116
Query: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 796
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1117 SCPSGLVFKYNVKACNSSCRSLSERD----RSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1172
Query: 797 SSCGCTFQGLQLAPGQEVWADE----------LCQRRC-----TCNGATHQVTCRDKQS- 840
S C C + PG+ + D+ LCQ C+G V C D ++
Sbjct: 1173 SQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1232
Query: 841 --------------------------CPAG------------------------------ 844
CP G
Sbjct: 1233 RRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVT 1292
Query: 845 ----ERCSVQNGLLGCYPDRFGT-CQGSGDPHYVSFDGRRFDFMGTCTY-LLVGSCGQNA 898
C+ G C + T C G+ H +FDG+ + F G C Y L CG
Sbjct: 1293 SVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN 1352
Query: 899 ALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG 958
FR+L E+ ++ +R + V + + ++ G+V + +
Sbjct: 1353 G--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---DGKVTAVKSTESKKCELNAN 1407
Query: 959 QVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRG 1018
+ G +++ G+ V +D N R++ + ++ +CGLCGN NGD DD R
Sbjct: 1408 AYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 1467
Query: 1019 GGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFREC 1078
A+ AL FGNSW +T C T P DS + + +C IL D FR+C
Sbjct: 1468 SSVASGALEFGNSW--KTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRD--STFRDC 1522
Query: 1079 HSKLDPQGAVRDCVYDRCL--LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSC 1136
H+K+DP C+ + C + G+ C A+A YA AC A G V WR LCP+ C
Sbjct: 1523 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYC 1581
Query: 1137 PPHS-------HYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGES---CL 1184
++ HYE C +C D V G S EGC C + E+ C+
Sbjct: 1582 DYYNAPGECRWHYEPCGTVTAKTCKDQLV-GQKFSSLLEGCYAKCPDSAPYLDENTMKCV 1640
Query: 1185 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS 1227
L+ C C + P G C C+C G L E++
Sbjct: 1641 SLSECSCFYNDVI-PAGGVI--EDNCGRTCYCIAGQLECSETA 1680
Score = 147 bits (371), Expect = 3e-34
Identities = 149/508 (29%), Positives = 200/508 (39%), Gaps = 77/508 (15%)
Query: 3538 CPAHSHYELCGDS-----CPGSCPSLSAPEGCESA-CREGCVCDAGFVL-SGDTCVPVGQ 3590
C + Y C D +C + + P E+ C+ GC C G V S CV
Sbjct: 1217 CSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPND 1276
Query: 3591 CGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVG 3650
C C R Y G GC+ C C +G SC + C
Sbjct: 1277 CPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SCTQNEC------------------- 1313
Query: 3651 STTCQASGDPHYTTFDGHRFDFMGTCVY-VLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 3709
T C G+ H TFDG + F G C Y L CG G F +L E+V ++
Sbjct: 1314 QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT--FRILTESVPCCEDGLTC 1371
Query: 3710 TRVITVQVANFTLRLEQRQWKVT-VNGVDMKLPVVLANGQIRASQH--GSDVVIETDFGL 3766
+R I V + + L+ KVT V + K + AN S H G ++++ G+
Sbjct: 1372 SRKIIVAFQDQNIVLQDG--KVTAVKSTESKKCELNANAY---SIHTVGLYLILKFQNGI 1426
Query: 3767 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVP 3826
V +D + V + N+ +CGLCGN NGD KDDF S A A EFGNSW+
Sbjct: 1427 IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---- 1482
Query: 3827 DSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPL 3886
C A P D P +K C +L T CH VDP
Sbjct: 1483 -----TSQECSDTVAQTFPCDSNPYCKAWAVRK---CEILRDST--FRDCHNKVDPSAYH 1532
Query: 3887 KDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNS------ 3938
CI + C G C+ + Y AC A G V WR CP+ C +
Sbjct: 1533 DVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECR 1591
Query: 3939 -HYELC----ADTC--SLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCY 3990
HYE C A TC L S+ L +GC C + +L N CV + +C C+
Sbjct: 1592 WHYEPCGTVTAKTCKDQLVGQKFSSLL---EGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648
Query: 3991 HNGVYYEPEQTVLIDNCRQQCTCHVGKV 4018
+N V P V+ DNC + C C G++
Sbjct: 1649 YNDVI--PAGGVIEDNCGRTCYCIAGQL 1674
Score = 145 bits (367), Expect = 8e-34
Identities = 148/515 (28%), Positives = 199/515 (38%), Gaps = 91/515 (17%)
Query: 2337 CPAHSHYELCGDS-----CPGSCPSLSAPEGCESA-CREGCVCDAGFVL-SGDTCVPVGQ 2389
C + Y C D +C + + P E+ C+ GC C G V S CV
Sbjct: 1217 CSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPND 1276
Query: 2390 CGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVG 2449
C C R Y G GC+ C C +G SC + C
Sbjct: 1277 CPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SCTQNEC------------------- 1313
Query: 2450 STTCQASGDPHYTTFDGRRFDFMGTCVY-VLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 2508
T C G+ H TFDG+ + F G C Y L CG G F +L E+V ++
Sbjct: 1314 QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT--FRILTESVPCCEDGLTC 1371
Query: 2509 TRVITVQVANFTLRLEQRQWKVT-VNGVDMKLPVVLANGQIRASQH--GSDVVIETDFGL 2565
+R I V + + L+ KVT V + K + AN S H G ++++ G+
Sbjct: 1372 SRKIIVAFQDQNIVLQDG--KVTAVKSTESKKCELNANAY---SIHTVGLYLILKFQNGI 1426
Query: 2566 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW----- 2620
V +D + V + N+ +CGLCGN NGD KDDF S A A EFGNSW
Sbjct: 1427 IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1486
Query: 2621 --EEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKL 2678
+ V PC P C K C +L T CH
Sbjct: 1487 CSDTVAQTFPCDSNPYC-------------------KAWAVRKCEILRDST--FRDCHNK 1525
Query: 2679 VDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQN 2736
VDP CI + C G C+ + Y AC A G V WR CP+ C
Sbjct: 1526 VDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYY 1584
Query: 2737 S-------HYELC----ADTC--SLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVP 2782
+ HYE C A TC L S+ L +GC C + +L N CV
Sbjct: 1585 NAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLL---EGCYAKCPDSAPYLDENTMKCVS 1641
Query: 2783 IQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKV 2817
+ +C C++N P V+ DNC + C C G++
Sbjct: 1642 LSECSCFYNDVI--PAGGVIEDNCGRTCYCIAGQL 1674
Score = 145 bits (366), Expect = 1e-33
Identities = 138/475 (29%), Positives = 192/475 (40%), Gaps = 68/475 (14%)
Query: 1166 CHEGCVCDEGFALSGES-CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
C GC C EG + + C+ C C G + G GC+ C C +G SC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SC 1308
Query: 1225 ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVY-VLAQTCG 1283
+ C + C G+ H TFDG+ + F G C Y L CG
Sbjct: 1309 TQNEC-------------------QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCG 1349
Query: 1284 TRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVT-VNGVDMKLPVVL 1342
G F +L E+V ++ +R I V + + L+ KVT V + K +
Sbjct: 1350 HENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDG--KVTAVKSTESKKCELN 1405
Query: 1343 ANGQIRASQH--GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDD 1400
AN S H G ++++ G+ V +D + V + N+ ++CGLCGN NGD KDD
Sbjct: 1406 ANAY---SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 1401 FQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIPSHKCPPELEKKYQKEE 1459
F S A A EFGNSW+ S + T PC D P C +K
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP--YCKAWAVRK----- 1510
Query: 1460 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGG 1517
C +L T CH VDP CI + C G C+ + Y AC A G
Sbjct: 1511 -CEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV 1567
Query: 1518 HVEPWRTETFCPMECPPNS-------HYELCADTCSLGCSALSAPPQCQ---DGCAEGCQ 1567
V WR CP+ C + HYE C + C + +GC C
Sbjct: 1568 CVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP 1626
Query: 1568 CDSGFL-YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE 1621
+ +L N CV + +C C++N V P V+ DNC + C C AG+ + C E
Sbjct: 1627 DSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIEDNCGRTCYCIAGQ-LECSE 1678
Score = 144 bits (363), Expect = 2e-33
Identities = 139/532 (26%), Positives = 207/532 (38%), Gaps = 89/532 (16%)
Query: 4769 CREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC 4827
C+ GC C G V S CV C C GR Y G V G C EC TC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG--CN---EC------TC 1301
Query: 4828 QEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY-VLAQVC 4886
+G+ EC+ CH G G H T DG+ Y G C Y L C
Sbjct: 1302 IKGSWSCTQNECQT-----ICHIYGEG--------HVRTFDGKSYSFDGLCQYSFLEDYC 1348
Query: 4887 HPKPGDEDFSIVLE-----KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDG-EAVALPVAV 4940
+ G F I+ E ++ ++++V Q + L G+ V E+ +
Sbjct: 1349 GHENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNA 1406
Query: 4941 GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLP 5000
+ G ++L+ G+ +++D + L + + + G++CGLCGN NG+ DDF
Sbjct: 1407 NAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 1466
Query: 5001 NGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESN--------EACGQ 5052
S AS FG +W+ +S+ C + +T P +SN C
Sbjct: 1467 YSSVASGALEFGNSWK---TSQECSD----------TVAQTFPCDSNPYCKAWAVRKCEI 1513
Query: 5053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKP 5110
LR+ F C + PS Y C+ + CA +G C ++A Y AC A GV V
Sbjct: 1514 LRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1570
Query: 5111 WRTDSFCPLHCPAHS-------HYSIC----TRTCQGSCAA---LSGLTGCTTRCFEGCE 5156
WR + CP++C ++ HY C +TC+ S L GC +C +
Sbjct: 1571 WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAP 1630
Query: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
D + C+ + +C C +N +P ++ +C C C + L C P
Sbjct: 1631 YLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDNCGRTCYCIAGQ-LECSET-APTN 1683
Query: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTS-PGVYELSSRCPG 5267
V T +LS GA +T G S P + SS G
Sbjct: 1684 STFAVS-------TTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTG 1728
Score = 142 bits (357), Expect = 1e-32
Identities = 152/596 (25%), Positives = 225/596 (37%), Gaps = 96/596 (16%)
Query: 3060 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 3118
G CP E E G C + G F C + +K +D D+
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 3119 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 3174
C + C + G E WR+ V CE CPE Y+ CGP PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 3175 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 3230
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 3231 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 3290
C C S CT A C C+ G T DG +++
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 3291 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 3339
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 3340 HSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 3399
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 3400 V--PAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 3449
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 3450 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 3509
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 3510 AVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE---GCES 3566
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 3567 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 3621
+GC C DA + + CV QC C +D G+ + D+ C CR+G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDG 1202
Score = 140 bits (354), Expect = 3e-32
Identities = 152/596 (25%), Positives = 224/596 (37%), Gaps = 96/596 (16%)
Query: 1859 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1917
G CP E E G C + G F C + +K +D D+
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 1918 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGSPCPASCPSPAPL 1973
C + C + G E WR+ V CE CPE Y+ CG PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 1974 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 2029
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 2030 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFN 2089
C C S CT A C C+ G T DG ++N
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 2090 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 2138
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 2139 HSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 2198
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 2199 V--PAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 2248
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 2249 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 2308
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 2309 AVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE---GCES 2365
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 2366 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 2420
+GC C DA + + CV QC C +D G+ + D+ C CR+G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDG 1202
Score = 139 bits (349), Expect = 1e-31
Identities = 107/399 (26%), Positives = 167/399 (41%), Gaps = 34/399 (8%)
Query: 445 EGMQCAAG-QRCQVVGGKAGCVA-ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-L 501
EG + G C + G C E +C G+ H TFDG+ Y G C Y+ +E
Sbjct: 1288 EGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDY 1347
Query: 502 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
C ++ F + ++ ++ + V ++ L G+V V +
Sbjct: 1348 CGHENG--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKK---C 1402
Query: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
L+ ++ G +++ G++V +D + +L++ L + +VCGLCGN NGD DD
Sbjct: 1403 ELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
F T ++A A+EF +SWK C D P C R C +L D
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDSNPYCKAWAVRKCEILR--D 1516
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPA 739
F CH+ +DP + + C+ + C + G+ L C ++ YA+AC +G+ V WR P
Sbjct: 1517 STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPN 1575
Query: 740 NCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSGRPCVEGCVC-----LPGFV 787
CP+ C P R YE CG +C S +EGC P
Sbjct: 1576 LCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS--LLEGCYAKCPDSAPYLD 1633
Query: 788 ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 826
+ CV S C C + + A G ++ C R C C
Sbjct: 1634 ENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1669
Score = 136 bits (343), Expect = 5e-31
Identities = 153/599 (25%), Positives = 223/599 (37%), Gaps = 102/599 (17%)
Query: 4261 GSCPTCPEDRLEQYE-GPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 4319
G CP E E G C + G F C + +K +D D+
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKI---IGTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 4320 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 4375
C + C + G E WR+ V CE CPE Y+ CGP PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 4376 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 4431
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 4432 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 4491
C C S CT A C C+ G T DG +++
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 4492 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 4540
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 4541 HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 4600
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 4601 V--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 4650
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 4651 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 4710
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 4711 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE---GCES 4767
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 4768 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC---ERRCECGPG 4822
+GC C DA + + CV QC C Y EV PG + +C C G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLIHIDDNKCVCRDG 1202
Score = 131 bits (330), Expect = 2e-29
Identities = 136/590 (23%), Positives = 224/590 (37%), Gaps = 80/590 (13%)
Query: 648 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV 707
+CEDG Q+ C ++E CG + L + + C+ + C
Sbjct: 681 VCEDGIQH----CNKIIGTYFEK---CGKVAALSNDYKMI------------CIDEYCQT 721
Query: 708 GGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPACPTSCN 763
++ S C S ++ C G + WRS ++ CP Y+ CGP+ P +C+
Sbjct: 722 R-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCS 780
Query: 764 GAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQEVWADEL 819
A + CV GC C G+ + G CV + C C G PG+ +
Sbjct: 781 NVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--REGP 835
Query: 820 CQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRR 879
C +CTC A T + CP RC V+ L +FDG +
Sbjct: 836 CGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------TTFDGVK 872
Query: 880 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYP 939
++F G C +L V + ++ ++ + G+ S T + K +
Sbjct: 873 YNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSD-- 928
Query: 940 GQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDF--GLTVTYDWNARVTAKVPSSYA 996
+ +D ++ + +D ++Q+F + V T F L + ++ +P +
Sbjct: 929 -GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQF 986
Query: 997 EALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVA 1056
GLCG++N DD + AF NSW+ C P C ++
Sbjct: 987 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE---MMSCPKGNPSSCISIE---- 1039
Query: 1057 QQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1116
++ ++ CGIL D GP CH ++P+ +C C LC L Y AC
Sbjct: 1040 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 1099
Query: 1117 QAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CHEGCVCD 1173
+ WR+ LC SCP ++ C SC L C E +GC C
Sbjct: 1100 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 1158
Query: 1174 EGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1222
+ + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1159 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDGILL 1205
Score = 127 bits (319), Expect = 3e-28
Identities = 126/506 (24%), Positives = 199/506 (39%), Gaps = 87/506 (17%)
Query: 1982 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 2041
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 2042 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEY-LLSA 2100
CT Q+ CQ + C +G+ H T DG ++F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 2101 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2158
C G EN T + E ++ +R + + + ++ L +V V
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDG-----KVTAVKS 1396
Query: 2159 TLPFQLDSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYN 2215
T + + +A H G +++ +G+ + +D ++ + + + + G +CGLCGN N
Sbjct: 1397 TESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNN 1456
Query: 2216 QDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVI 2269
D DD A G G +Q C + V++ PC C ++
Sbjct: 1457 GDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRKCEIL 1514
Query: 2270 SATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQLREW 2327
D CH V P+ Y C+ + AC ++G G C AVA Y AC A G + W
Sbjct: 1515 --RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SW 1571
Query: 2328 RRPDFCPFQCPAHS-------HYELCGDSCPGSCPS-------LSAPEGCESACREGCVC 2373
R+P+ CP C ++ HYE CG +C S EGC + C
Sbjct: 1572 RKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP----- 1626
Query: 2374 DAGFVLSGDT--CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCG 2431
D+ L +T CV + +C C ++D P G C C C G++ C ++
Sbjct: 1627 DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSETA-- 1680
Query: 2432 PHETCRPSGGSLGCVAVGSTTCQASG 2457
P+ + +TT ++G
Sbjct: 1681 ------PTNSTFAVSTTTATTILSTG 1700
Score = 127 bits (319), Expect = 3e-28
Identities = 124/482 (25%), Positives = 191/482 (39%), Gaps = 87/482 (18%)
Query: 4384 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 4443
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 4444 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSA 4502
CT Q+ CQ + C +G+ H T DG + F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 4503 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 4560
C G EN T + E ++ +R + + + ++ L DG
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---------DGKVT 1392
Query: 4561 ALPF------QLDSLLHA-HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLC 4613
A+ +L++ ++ H G +++ +G+ + +D ++ + + + + +CGLC
Sbjct: 1393 AVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLC 1452
Query: 4614 GNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDA 4667
GN N D DD A G G +Q C + V++ PC
Sbjct: 1453 GNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRK 1510
Query: 4668 CGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQ 4725
C ++ D CH V P+ Y C+ + AC ++G G C AVA Y AC A G
Sbjct: 1511 CEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVC 1568
Query: 4726 LGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS-------LSAPEGCESACRE 4771
+ WR+P+ CP+ C ++ HYE CG +C S EGC + C
Sbjct: 1569 V-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP- 1626
Query: 4772 GCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 4829
D+ L +T CV + +C C ++ P G V C R C C G + C E
Sbjct: 1627 ----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSE 1678
Query: 4830 GA 4831
A
Sbjct: 1679 TA 1680
Score = 127 bits (318), Expect = 4e-28
Identities = 126/506 (24%), Positives = 198/506 (39%), Gaps = 87/506 (17%)
Query: 3183 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 3242
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 3243 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSA 3301
CT Q+ CQ + C +G+ H T DG + F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 3302 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 3359
C G EN T + E ++ +R + + + ++ L +V V
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDG-----KVTAVKS 1396
Query: 3360 TLPFQLDSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYN 3416
T + + +A H G +++ +G+ + +D ++ + + + + G +CGLCGN N
Sbjct: 1397 TESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNN 1456
Query: 3417 QDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVI 3470
D DD A G G +Q C + V++ PC C ++
Sbjct: 1457 GDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRKCEIL 1514
Query: 3471 SATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQLREW 3528
D CH V P+ Y C+ + AC ++G G C AVA Y AC A G + W
Sbjct: 1515 --RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SW 1571
Query: 3529 RRPDFCPFQCPAHS-------HYELCGDSCPGSCPS-------LSAPEGCESACREGCVC 3574
R+P+ CP C ++ HYE CG +C S EGC + C
Sbjct: 1572 RKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP----- 1626
Query: 3575 DAGFVLSGDT--CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCG 3632
D+ L +T CV + +C C ++D P G C C C G++ C ++
Sbjct: 1627 DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSETA-- 1680
Query: 3633 PHETCRPSGGSLGCVAVGSTTCQASG 3658
P+ + +TT ++G
Sbjct: 1681 ------PTNSTFAVSTTTATTILSTG 1700
Score = 126 bits (316), Expect = 7e-28
Identities = 131/545 (24%), Positives = 193/545 (35%), Gaps = 80/545 (14%)
Query: 4694 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCG 4749
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 772
Query: 4750 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGE 4805
S P +C +++ + +S C GC C G++L CV +C C G Y GE
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 4806 VFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHY 4864
V R CG +C +D +C C GRC G
Sbjct: 831 V--------REGPCG----------------SQCTCQDAKWSCTEALCPGRCKVEGS-SL 865
Query: 4865 ITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQG 4924
T DG Y+ G+C ++ +ED+SI +E Q V+L
Sbjct: 866 TTFDGVKYNFPGNCHFLAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLN 915
Query: 4925 QQVTVDGEAVALPVAVGRVRVTAEG------------RNMVLQTTK----GLRLLFDGDA 4968
V VD V ++ +G + LQ L++
Sbjct: 916 SSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 4969 HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGC 5028
L +S+P GLCG++N DDF+ + + F +W KG
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG----- 1030
Query: 5029 GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKA 5088
P C E+ A CG L + GP A+C +++P Y +C C + +
Sbjct: 1031 NPSSCISIEKEKFA----ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 5089 FLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGC 5147
LC L Y AC + WRT C CP+ + + C SC +LS C
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 5148 TTR--CFEGCECDD-RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 5204
+GC C D + ++G C+ C C N + + D +C C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NKCVCRDGI 1203
Query: 5205 GLTCQ 5209
L CQ
Sbjct: 1204 -LLCQ 1207
Score = 116 bits (291), Expect = 5e-25
Identities = 144/607 (23%), Positives = 224/607 (36%), Gaps = 120/607 (19%)
Query: 2660 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 2718
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 2719 QVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLY 2775
E WR+++ E CP+ Y+ C + CS + AP Q + C GC C G+L
Sbjct: 745 TFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNV-APFQDSE-CVSGCTCPEGYLL 802
Query: 2776 NGQA----CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVC 2831
+ CV +C C +G Y+P + V C QCTC K C E C PG+
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS-CTEALC-PGR-- 857
Query: 2832 QPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 2891
CK +G +FDG K++
Sbjct: 858 -------------------------CKVEGSS------------------LTTFDGVKYN 874
Query: 2892 FQGTCNYV----------LATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 2941
F G C+++ + CP S Q T T N P YV
Sbjct: 875 FPGNCHFLAVHNEDWSISVELRPCP--SGQTGTCLNSVTLLLNSSVPVDKYV-------F 925
Query: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNW 2998
++ ++ D K+R G + +I + +S L V + LQ+
Sbjct: 926 NSDGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 2999 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 3058
++ V++P + GLCG+ + +D + L + + SW C
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGN 1031
Query: 3059 RGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 3118
SC + +++ + CG L +G P +CH V P+ + + C C +D
Sbjct: 1032 PSSCISIEKEKFAERH----CGILLDSSG-PLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 3119 ILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPA 3178
LC L +YV AC I WR + CE +CP ++ C +SC S +
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 3179 VCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 3237
E V+GC C DA + + CV L + C C+ N + G D +C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHIDDN-----KCVC 1199
Query: 3238 GGGSLVC 3244
G L+C
Sbjct: 1200 RDGILLC 1206
Score = 116 bits (290), Expect = 7e-25
Identities = 143/605 (23%), Positives = 224/605 (37%), Gaps = 116/605 (19%)
Query: 3861 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 3919
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 3920 HVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLY 3976
E WR+++ E CP+ Y+ C + CS + AP Q + C GC C G+L
Sbjct: 745 TFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNV-APFQDSE-CVSGCTCPEGYLL 802
Query: 3977 NGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVC 4032
+ CV +C C +G Y+P + V C QCTC K C E C PG+
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS-CTEALC-PGR-- 857
Query: 4033 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 4092
CK +G +FDG K++
Sbjct: 858 -------------------------CKVEGSS------------------LTTFDGVKYN 874
Query: 4093 FQGTCNYV--------LATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGT 4144
F G C+++ ++ P S Q T T N P YV +
Sbjct: 875 FPGNCHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYV-------FNS 927
Query: 4145 NISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRV 4201
+ ++ D K+R G + +I + +S L V + LQ+ ++
Sbjct: 928 DGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQVETYFHVKLQIQIVPVMQL 977
Query: 4202 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 4261
V++P + GLCG+ + +D + L + + SW C
Sbjct: 978 YVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGNPS 1033
Query: 4262 SCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL 4321
SC + +++ + CG L + GP +CH V P+ + + C C +D L
Sbjct: 1034 SCISIEKEKFAERH----CGILLD-SSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCL 1088
Query: 4322 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVC 4381
C L +YV AC I WR + CE +CP ++ C +SC S +
Sbjct: 1089 CTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDV 1147
Query: 4382 EGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 4440
E V+GC C DA + + CV L + C C+ N + G D +C
Sbjct: 1148 EDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHIDDN-----KCVCRD 1201
Query: 4441 GSLVC 4445
G L+C
Sbjct: 1202 GILLC 1206
Score = 115 bits (288), Expect = 1e-24
Identities = 142/607 (23%), Positives = 221/607 (36%), Gaps = 120/607 (19%)
Query: 1459 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 1517
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 1518 HVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 1574
E WR+++ E CP Y+ C + CS ++ P C GC C G+L
Sbjct: 745 TFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVA--PFQDSECVSGCTCPEGYLL 802
Query: 1575 NGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
+ CV +C C +G Y+P + V C QCTC K C E C PG+
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS-CTEALC-PGR-- 857
Query: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
CK +G +FDG K++
Sbjct: 858 -------------------------CKVEGSS------------------LTTFDGVKYN 874
Query: 1691 FQGTCNYV----------LATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
F G C+++ + CP S Q T T N P YV
Sbjct: 875 FPGNCHFLAVHNEDWSISVELRPCP--SGQTGTCLNSVTLLLNSSVPVDKYV-------F 925
Query: 1741 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNW 1797
++ ++ D K+R G + +I + +S L V + LQ+
Sbjct: 926 NSDGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 1798 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 1857
++ V++P + GLCG+ + +D + L + + SW C
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGN 1031
Query: 1858 RGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1917
SC + +++ + CG L +G P +CH V P+ + + C C +D
Sbjct: 1032 PSSCISIEKEKFAERH----CGILLDSSG-PLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 1918 ILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPA 1977
LC L +YV AC I WR + CE +CP ++ C +SC S +
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 1978 VCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 2036
E V+GC C DA + + CV L + C C+ N + G D +C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHIDDN-----KCVC 1199
Query: 2037 GGGSLVC 2043
G L+C
Sbjct: 1200 RDGILLC 1206
Score = 61.6 bits (148), Expect = 2e-08
Identities = 52/200 (26%), Positives = 83/200 (41%), Gaps = 33/200 (16%)
Query: 5060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--F 5116
F C V + S ++ D Q DK C + + + C + G + WR+DS
Sbjct: 697 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 756
Query: 5117 CPLH-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPV 5171
C CP Y C + +C+ ++ + C GC C + +LL +G C+
Sbjct: 757 CETQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLK 814
Query: 5172 QDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 5230
+C C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 815 AECPCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE-------- 861
Query: 5231 TRGLCVLSVGANLTTFDGAR 5250
G++LTTFDG +
Sbjct: 862 ---------GSSLTTFDGVK 872
Score = 60.1 bits (144), Expect = 6e-08
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 26/235 (11%)
Query: 5151 CFEGCECDDRFLL-SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 5209
C GC C + + S+G+C+ DC C+ GR S+ + C+E C+C S +C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYD-EGSVTSVGCNE-CTCIKGSW-SCT 1309
Query: 5210 AAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQ 5269
C +C + E ++ TFDG + Y G +
Sbjct: 1310 QNECQT--ICHIYGEG----------------HVRTFDGKSYSFDGLCQYSFLEDYCGHE 1351
Query: 5270 NTIPWYRVVAE-VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASV 5328
N +R++ E V C ++ + FQD + L K V E A+
Sbjct: 1352 NGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTE-SKKCELNANA 1408
Query: 5329 SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
T L+++ + G+ V N +++VI+ + GK+CG CGN +GD +D+
Sbjct: 1409 YSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 1463
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 243 bits (621), Expect = 3e-63
Identities = 255/1031 (24%), Positives = 400/1031 (38%), Gaps = 156/1031 (15%)
Query: 1091 CVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--LCPLS-CPPHSHYEACS 1146
C+ + C ++ CD + + C + G T WRS+ +C CP Y+ C
Sbjct: 714 CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 772
Query: 1147 YGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GES--CLPLASCGCVHQGTYHPPGQ 1202
P +C + V SEC GC C EG+ L GE C+ A C C GT + PG+
Sbjct: 773 PSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 1203 TFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTT 1262
GP C S C CQ+ SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL------------------TT 867
Query: 1263 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 1322
FDG +++F G C ++ +++ E +G+ + N ++ +
Sbjct: 868 FDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920
Query: 1323 EQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VT 1377
++ + TV ++ + +I+ S + +ET F +++ +V ++ V+
Sbjct: 921 DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 980
Query: 1378 VPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPG 1437
+P N + GLCG+YN +DDF + F NSWE + CP G
Sbjct: 981 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKG 1030
Query: 1438 S-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 1496
+ CI +EK+ E CG+L +GPL+SCH +V+P+ ++C C
Sbjct: 1031 NPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1083
Query: 1497 NLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPP 1556
+ LC+ + YV AC ++ WRT C CP ++ C+ C +LS
Sbjct: 1084 SQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERD 1142
Query: 1557 Q---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDN----CR-- 1606
+ +D +GC C N + CV QC CY N +P + + ID+ CR
Sbjct: 1143 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 1607 ------------QQC--------------------TCHAGKGMVCQEH-SCKPGQVCQPS 1633
Q C TC V E+ CK G C P
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFC-PE 1261
Query: 1634 GGILS----CVTKDPC-----------HGVTCRPQETCKEQGGQGVCLPN-YEATCWLWG 1677
G + + CV + C VT C G C N + C ++G
Sbjct: 1262 GMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYG 1321
Query: 1678 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTV 1737
+ H +FDG+ + F G C Y C + F + T++ ++ R + V
Sbjct: 1322 EGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN----GTFRILTESVPCCEDGLTCSRKIIV 1377
Query: 1738 AALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNW 1797
A NI + + GKV + + S+ +L G+ V +D N
Sbjct: 1378 AFQDQNIVL---QDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNT 1434
Query: 1798 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 1857
R+ V L +++G VCGLCGN + + +D ++A +G SW+ C D
Sbjct: 1435 RLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTV 1491
Query: 1858 RGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1917
+ P C + + C L T F CH V P ++ C+ + C +
Sbjct: 1492 AQTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGK 1547
Query: 1918 IL--CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGSPCPASCP 1968
L C A+A Y AC A GV + WR C + C + HYE CG+ +C
Sbjct: 1548 YLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1606
Query: 1969 SP-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADG 2026
++ EG C C A ++ + +CV L+ C C+ N G +
Sbjct: 1607 DQLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IED 1661
Query: 2027 TCSQWCRCGPG 2037
C + C C G
Sbjct: 1662 NCGRTCYCIAG 1672
Score = 231 bits (590), Expect = 1e-59
Identities = 249/1030 (24%), Positives = 391/1030 (37%), Gaps = 154/1030 (14%)
Query: 2292 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCG 2347
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 772
Query: 2348 DSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDDRYYPLGQ 2403
S P +C +++ + +S C GC C G++L CV +C C Y G+
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 2404 TFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTT 2463
GP C S C C++ + SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDA-KWSCTEALCPGR--CKVEGSSL------------------TT 867
Query: 2464 FDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 2523
FDG +++F G C ++ +++ E +G+ + N ++ +
Sbjct: 868 FDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920
Query: 2524 EQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VT 2578
++ + TV ++ + +I+ S + +ET F +++ +V ++ V+
Sbjct: 921 DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 980
Query: 2579 VPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPG 2638
+P N + GLCG+YN +DDF + F NSWE + +CP G
Sbjct: 981 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKG 1030
Query: 2639 S-EGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 2697
+ CI +EK+ E CG+L +GPL+SCH +V+P+ ++C C
Sbjct: 1031 NPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1083
Query: 2698 NLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSA-- 2755
+ LC+ + YV AC + WR C CP ++ C+ C +LS
Sbjct: 1084 SQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERD 1142
Query: 2756 -PLQCPDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGAYYEPEQTVLIDN----CR-- 2807
D +GC C N + CV QC CY N +P + + ID+ CR
Sbjct: 1143 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 2808 ------------QQC--------------------TCHVGKVVVCQEH-SCKPGQVC--- 2831
Q C TC + V E+ CK G C
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEG 1262
Query: 2832 --QPSGGILSCVNKDPCH---------GVTCRPQETCKEQGGQGVCLPNY-EATCWLWGD 2879
+ S GI N PC VT C G C N + C ++G+
Sbjct: 1263 MVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGE 1322
Query: 2880 PHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVA 2939
H +FDG+ + F G C Y C + F + T++ ++ R + VA
Sbjct: 1323 GHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT----FRILTESVPCCEDGLTCSRKIIVA 1378
Query: 2940 ALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWR 2999
NI + GKV + + S+ +L G+ V +D N R
Sbjct: 1379 FQDQNIVLQD---GKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTR 1435
Query: 3000 VDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECR 3059
+ V L +++G VCGLCGN + + +D ++A +G SW+ C D
Sbjct: 1436 LSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTVA 1492
Query: 3060 GSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDI 3119
+ P C + + C L T F CH V P ++ C+ + C +
Sbjct: 1493 QTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGKY 1548
Query: 3120 L--CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPS 3170
L C A+A Y AC A GV + WR C + C + HYE CG +C
Sbjct: 1549 LGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1607
Query: 3171 P-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADGT 3228
++ EG C C A ++ + +CV L+ C C+ N G +
Sbjct: 1608 QLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IEDN 1662
Query: 3229 CSQWCRCGPG 3238
C + C C G
Sbjct: 1663 CGRTCYCIAG 1672
Score = 231 bits (589), Expect = 1e-59
Identities = 248/1031 (24%), Positives = 394/1031 (38%), Gaps = 156/1031 (15%)
Query: 3493 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCG 3548
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 772
Query: 3549 DSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDDRYYPLGQ 3604
S P +C +++ + +S C GC C G++L CV +C C Y G+
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 3605 TFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTT 3664
GP C S C C++ + SC + C C+ G SL TT
Sbjct: 831 V-REGP-CGSQCTCQDA-KWSCTEALCPGR--CKVEGSSL------------------TT 867
Query: 3665 FDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRL 3724
FDG +++F G C ++ +++ E +G+ + N ++ +
Sbjct: 868 FDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPV 920
Query: 3725 EQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VT 3779
++ + TV ++ + +I+ S + +ET F +++ +V ++ V+
Sbjct: 921 DKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 980
Query: 3780 VPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPG 3839
+P N + GLCG+YN +DDF + F NSWE + +CP G
Sbjct: 981 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKG 1030
Query: 3840 S-AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGG 3898
+ + CI +EK+ E CG+L +GPL+SCH +V+P+ ++C C
Sbjct: 1031 NPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1083
Query: 3899 NLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSA-- 3956
+ LC+ + YV AC ++ WR C CP ++ C+ C +LS
Sbjct: 1084 SQDCLCTILGNYVKACAEKETYIVGWRTG-LCEHSCPSGLVFKYNVKACNSSCRSLSERD 1142
Query: 3957 -PLQCPDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDN----CR-- 4008
D +GC C N + CV QC CY N +P + + ID+ CR
Sbjct: 1143 RSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDDNKCVCRDG 1202
Query: 4009 ------------QQC--------------------TCHVGKVVVCQEH-SCKPGQVCQPS 4035
Q C TC + V E+ CK G C P
Sbjct: 1203 ILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFC-PE 1261
Query: 4036 GGILS----CVTKDPCH-----------GVTCRPQETCKEQGGQGVCLPNY-EATCWLWG 4079
G + + CV + C VT C G C N + C ++G
Sbjct: 1262 GMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIKGSWSCTQNECQTICHIYG 1321
Query: 4080 DPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTV 4139
+ H +FDG+ + F G C Y C + F + T++ ++ R + V
Sbjct: 1322 EGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT----FRILTESVPCCEDGLTCSRKIIV 1377
Query: 4140 AALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNW 4199
A NI + GKV + + S+ +L G+ V +D N
Sbjct: 1378 AFQDQNIVLQD---GKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNT 1434
Query: 4200 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 4259
R+ V L +++G VCGLCGN + + +D ++A +G SW+ C D
Sbjct: 1435 RLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTV 1491
Query: 4260 RGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 4319
+ P C + + C L T F CH V P ++ C+ + C +
Sbjct: 1492 AQTFP-CDSNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGK 1547
Query: 4320 IL--CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCP 4370
L C A+A Y AC A GV + WR C + C + HYE CG +C
Sbjct: 1548 YLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCK 1606
Query: 4371 SP-APLTTPAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
++ EG C C A ++ + +CV L+ C C+ N G +
Sbjct: 1607 DQLVGQKFSSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IED 1661
Query: 4429 TCSQWCRCGPG 4439
C + C C G
Sbjct: 1662 NCGRTCYCIAG 1672
Score = 221 bits (563), Expect = 2e-56
Identities = 224/883 (25%), Positives = 339/883 (38%), Gaps = 146/883 (16%)
Query: 452 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 510
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 837 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 893
Query: 511 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566
+ G+ S L V V Y + T V N + R
Sbjct: 894 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 945
Query: 567 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 946 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 1005
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 1006 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1057
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1058 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEH 1116
Query: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 796
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1117 SCPSGLVFKYNVKACNSSCRSLSERD----RSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1172
Query: 797 SSCGCTFQGLQLAPGQEVWADE----------LCQRRC-----TCNGATHQVTCRDKQS- 840
S C C + PG+ + D+ LCQ C+G V C D ++
Sbjct: 1173 SQCDCYINDEVMQPGKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1232
Query: 841 --------------------------CPAG------------------------------ 844
CP G
Sbjct: 1233 RRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVT 1292
Query: 845 ----ERCSVQNGLLGCYPDRFGT-CQGSGDPHYVSFDGRRFDFMGTCTY-LLVGSCGQNA 898
C+ G C + T C G+ H +FDG+ + F G C Y L CG
Sbjct: 1293 SVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHEN 1352
Query: 899 ALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADG 958
FR+L E+ ++ +R + V + + ++ G+V + +
Sbjct: 1353 G--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---DGKVTAVKSTESKKCELNAN 1407
Query: 959 QVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRG 1018
+ G +++ G+ V +D N R++ + ++ +CGLCGN NGD DD R
Sbjct: 1408 AYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRY 1467
Query: 1019 GGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFREC 1078
A+ AL FGNSW +T C T P DS + + +C IL D FR+C
Sbjct: 1468 SSVASGALEFGNSW--KTSQECSDTVAQTFP-CDSNPYCKAWAVRKCEILRD--STFRDC 1522
Query: 1079 HSKLDPQGAVRDCVYDRCL--LPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSC 1136
H+K+DP C+ + C + G+ C A+A YA AC A G V WR LCP+ C
Sbjct: 1523 HNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPNLCPVYC 1581
Query: 1137 PPHS-------HYEACSYGCPLSCGDLPVPGGCGSECHEGCV--CDEGFALSGES---CL 1184
++ HYE C +C D V G S EGC C + E+ C+
Sbjct: 1582 DYYNAPGECRWHYEPCGTVTAKTCKDQLV-GQKFSSLLEGCYAKCPDSAPYLDENTMKCV 1640
Query: 1185 PLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESS 1227
L+ C C + P G C C+C G L E++
Sbjct: 1641 SLSECSCFYNDVI-PAGGVI--EDNCGRTCYCIAGQLECSETA 1680
Score = 147 bits (371), Expect = 3e-34
Identities = 149/508 (29%), Positives = 200/508 (39%), Gaps = 77/508 (15%)
Query: 3538 CPAHSHYELCGDS-----CPGSCPSLSAPEGCESA-CREGCVCDAGFVL-SGDTCVPVGQ 3590
C + Y C D +C + + P E+ C+ GC C G V S CV
Sbjct: 1217 CSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPND 1276
Query: 3591 CGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVG 3650
C C R Y G GC+ C C +G SC + C
Sbjct: 1277 CPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SCTQNEC------------------- 1313
Query: 3651 STTCQASGDPHYTTFDGHRFDFMGTCVY-VLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 3709
T C G+ H TFDG + F G C Y L CG G F +L E+V ++
Sbjct: 1314 QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT--FRILTESVPCCEDGLTC 1371
Query: 3710 TRVITVQVANFTLRLEQRQWKVT-VNGVDMKLPVVLANGQIRASQH--GSDVVIETDFGL 3766
+R I V + + L+ KVT V + K + AN S H G ++++ G+
Sbjct: 1372 SRKIIVAFQDQNIVLQDG--KVTAVKSTESKKCELNANAY---SIHTVGLYLILKFQNGI 1426
Query: 3767 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVP 3826
V +D + V + N+ +CGLCGN NGD KDDF S A A EFGNSW+
Sbjct: 1427 IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---- 1482
Query: 3827 DSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPL 3886
C A P D P +K C +L T CH VDP
Sbjct: 1483 -----TSQECSDTVAQTFPCDSNPYCKAWAVRK---CEILRDST--FRDCHNKVDPSAYH 1532
Query: 3887 KDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNS------ 3938
CI + C G C+ + Y AC A G V WR CP+ C +
Sbjct: 1533 DVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECR 1591
Query: 3939 -HYELC----ADTC--SLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCY 3990
HYE C A TC L S+ L +GC C + +L N CV + +C C+
Sbjct: 1592 WHYEPCGTVTAKTCKDQLVGQKFSSLL---EGCYAKCPDSAPYLDENTMKCVSLSECSCF 1648
Query: 3991 HNGVYYEPEQTVLIDNCRQQCTCHVGKV 4018
+N V P V+ DNC + C C G++
Sbjct: 1649 YNDVI--PAGGVIEDNCGRTCYCIAGQL 1674
Score = 145 bits (367), Expect = 8e-34
Identities = 148/515 (28%), Positives = 199/515 (38%), Gaps = 91/515 (17%)
Query: 2337 CPAHSHYELCGDS-----CPGSCPSLSAPEGCESA-CREGCVCDAGFVL-SGDTCVPVGQ 2389
C + Y C D +C + + P E+ C+ GC C G V S CV
Sbjct: 1217 CSGGAEYVDCSDPKAQRRTNRTCSTRNIPVFDENLPCKRGCFCPEGMVRNSKGICVFPND 1276
Query: 2390 CGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVG 2449
C C R Y G GC+ C C +G SC + C
Sbjct: 1277 CPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SCTQNEC------------------- 1313
Query: 2450 STTCQASGDPHYTTFDGRRFDFMGTCVY-VLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 2508
T C G+ H TFDG+ + F G C Y L CG G F +L E+V ++
Sbjct: 1314 QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGT--FRILTESVPCCEDGLTC 1371
Query: 2509 TRVITVQVANFTLRLEQRQWKVT-VNGVDMKLPVVLANGQIRASQH--GSDVVIETDFGL 2565
+R I V + + L+ KVT V + K + AN S H G ++++ G+
Sbjct: 1372 SRKIIVAFQDQNIVLQDG--KVTAVKSTESKKCELNANAY---SIHTVGLYLILKFQNGI 1426
Query: 2566 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW----- 2620
V +D + V + N+ +CGLCGN NGD KDDF S A A EFGNSW
Sbjct: 1427 IVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE 1486
Query: 2621 --EEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKL 2678
+ V PC P C K C +L T CH
Sbjct: 1487 CSDTVAQTFPCDSNPYC-------------------KAWAVRKCEILRDST--FRDCHNK 1525
Query: 2679 VDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQN 2736
VDP CI + C G C+ + Y AC A G V WR CP+ C
Sbjct: 1526 VDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYY 1584
Query: 2737 S-------HYELC----ADTC--SLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVP 2782
+ HYE C A TC L S+ L +GC C + +L N CV
Sbjct: 1585 NAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLL---EGCYAKCPDSAPYLDENTMKCVS 1641
Query: 2783 IQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKV 2817
+ +C C++N P V+ DNC + C C G++
Sbjct: 1642 LSECSCFYNDVI--PAGGVIEDNCGRTCYCIAGQL 1674
Score = 145 bits (366), Expect = 1e-33
Identities = 138/475 (29%), Positives = 192/475 (40%), Gaps = 68/475 (14%)
Query: 1166 CHEGCVCDEGFALSGES-CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
C GC C EG + + C+ C C G + G GC+ C C +G SC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSW-SC 1308
Query: 1225 ESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVY-VLAQTCG 1283
+ C + C G+ H TFDG+ + F G C Y L CG
Sbjct: 1309 TQNEC-------------------QTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCG 1349
Query: 1284 TRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVT-VNGVDMKLPVVL 1342
G F +L E+V ++ +R I V + + L+ KVT V + K +
Sbjct: 1350 HENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDG--KVTAVKSTESKKCELN 1405
Query: 1343 ANGQIRASQH--GSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDD 1400
AN S H G ++++ G+ V +D + V + N+ ++CGLCGN NGD KDD
Sbjct: 1406 ANAY---SIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 1401 FQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIPSHKCPPELEKKYQKEE 1459
F S A A EFGNSW+ S + T PC D P C +K
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP--YCKAWAVRK----- 1510
Query: 1460 FCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCSNIHAYVSACQAAGG 1517
C +L T CH VDP CI + C G C+ + Y AC A G
Sbjct: 1511 -CEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGV 1567
Query: 1518 HVEPWRTETFCPMECPPNS-------HYELCADTCSLGCSALSAPPQCQ---DGCAEGCQ 1567
V WR CP+ C + HYE C + C + +GC C
Sbjct: 1568 CVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP 1626
Query: 1568 CDSGFL-YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQE 1621
+ +L N CV + +C C++N V P V+ DNC + C C AG+ + C E
Sbjct: 1627 DSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIEDNCGRTCYCIAGQ-LECSE 1678
Score = 144 bits (363), Expect = 2e-33
Identities = 139/532 (26%), Positives = 207/532 (38%), Gaps = 89/532 (16%)
Query: 4769 CREGCVCDAGFVL-SGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC 4827
C+ GC C G V S CV C C GR Y G V G C EC TC
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVG--CN---EC------TC 1301
Query: 4828 QEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSY-VLAQVC 4886
+G+ EC+ CH G G H T DG+ Y G C Y L C
Sbjct: 1302 IKGSWSCTQNECQT-----ICHIYGEG--------HVRTFDGKSYSFDGLCQYSFLEDYC 1348
Query: 4887 HPKPGDEDFSIVLE-----KNAAGDLQRLLVTVAGQVVSLAQGQQVTVDG-EAVALPVAV 4940
+ G F I+ E ++ ++++V Q + L G+ V E+ +
Sbjct: 1349 GHENGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNA 1406
Query: 4941 GRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLP 5000
+ G ++L+ G+ +++D + L + + + G++CGLCGN NG+ DDF
Sbjct: 1407 NAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTR 1466
Query: 5001 NGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESN--------EACGQ 5052
S AS FG +W+ +S+ C + +T P +SN C
Sbjct: 1467 YSSVASGALEFGNSWK---TSQECSD----------TVAQTFPCDSNPYCKAWAVRKCEI 1513
Query: 5053 LRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKP 5110
LR+ F C + PS Y C+ + CA +G C ++A Y AC A GV V
Sbjct: 1514 LRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCVS- 1570
Query: 5111 WRTDSFCPLHCPAHS-------HYSIC----TRTCQGSCAA---LSGLTGCTTRCFEGCE 5156
WR + CP++C ++ HY C +TC+ S L GC +C +
Sbjct: 1571 WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAP 1630
Query: 5157 CDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPG 5216
D + C+ + +C C +N +P ++ +C C C + L C P
Sbjct: 1631 YLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDNCGRTCYCIAGQ-LECSET-APTN 1683
Query: 5217 RVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTS-PGVYELSSRCPG 5267
V T +LS GA +T G S P + SS G
Sbjct: 1684 STFAVS-------TTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTG 1728
Score = 139 bits (350), Expect = 8e-32
Identities = 151/596 (25%), Positives = 224/596 (37%), Gaps = 96/596 (16%)
Query: 3060 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 3118
G CP E E G C + G F C + +K +D D+
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 3119 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 3174
C + C + G E WR+ V C CPE Y+ CGP PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 3175 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 3230
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 3231 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 3290
C C S CT A C C+ G T DG +++
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 3291 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 3339
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 3340 HSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 3399
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 3400 V--PAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 3449
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 3450 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 3509
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 3510 AVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE---GCES 3566
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 3567 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 3621
+GC C DA + + CV QC C +D G+ + D+ C CR+G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDG 1202
Score = 139 bits (349), Expect = 1e-31
Identities = 107/399 (26%), Positives = 167/399 (41%), Gaps = 34/399 (8%)
Query: 445 EGMQCAAG-QRCQVVGGKAGCVA-ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-L 501
EG + G C + G C E +C G+ H TFDG+ Y G C Y+ +E
Sbjct: 1288 EGSVTSVGCNECTCIKGSWSCTQNECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDY 1347
Query: 502 CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPV 561
C ++ F + ++ ++ + V ++ L G+V V +
Sbjct: 1348 CGHENG--TFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKK---C 1402
Query: 562 SLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADD 621
L+ ++ G +++ G++V +D + +L++ L + +VCGLCGN NGD DD
Sbjct: 1403 ELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDD 1462
Query: 622 FLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLD 681
F T ++A A+EF +SWK C D P C R C +L D
Sbjct: 1463 FTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDSNPYCKAWAVRKCEILR--D 1516
Query: 682 GPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPA 739
F CH+ +DP + + C+ + C + G+ L C ++ YA+AC +G+ V WR P
Sbjct: 1517 STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKPN 1575
Query: 740 NCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSGRPCVEGCVC-----LPGFV 787
CP+ C P R YE CG +C S +EGC P
Sbjct: 1576 LCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS--LLEGCYAKCPDSAPYLD 1633
Query: 788 ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 826
+ CV S C C + + A G ++ C R C C
Sbjct: 1634 ENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1669
Score = 138 bits (347), Expect = 2e-31
Identities = 151/596 (25%), Positives = 223/596 (37%), Gaps = 96/596 (16%)
Query: 1859 GSCPTCPEDRLEQYE-GPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1917
G CP E E G C + G F C + +K +D D+
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKII---GTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 1918 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGSPCPASCPSPAPL 1973
C + C + G E WR+ V C CPE Y+ CG PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 1974 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 2029
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 2030 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFN 2089
C C S CT A C C+ G T DG ++N
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 2090 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 2138
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 2139 HSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 2198
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 2199 V--PAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 2248
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 2249 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 2308
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 2309 AVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPE---GCES 2365
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 2366 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 2420
+GC C DA + + CV QC C +D G+ + D+ C CR+G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDG 1202
Score = 134 bits (336), Expect = 3e-30
Identities = 152/599 (25%), Positives = 222/599 (37%), Gaps = 102/599 (17%)
Query: 4261 GSCPTCPEDRLEQYE-GPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 4319
G CP E E G C + G F C + +K +D D+
Sbjct: 669 GDCPNAVGKSYEVCEDGIQHCNKI---IGTYFEKCGKVAALSNDYKMICIDEYCQTRDKT 725
Query: 4320 ILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCGPPCPASCPSPAPL 4375
C + C + G E WR+ V C CPE Y+ CGP PA+C + AP
Sbjct: 726 STCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVAPF 785
Query: 4376 TTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 4431
+ CV GC C G++L +CV L C C ++GT ++ G +G C
Sbjct: 786 Q-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVYQPGEV--REGPCG 837
Query: 4432 QWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFD 4491
C C S CT A C C+ G T DG +++
Sbjct: 838 SQCTCQDAKWS--CTEALC--------------------PGRCKVEGSS-LTTFDGVKYN 874
Query: 4492 FQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL----------QIYN 4540
F G C +L + E+++++V S Q + SVTL ++N
Sbjct: 875 FPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFN 926
Query: 4541 HSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLR 4600
T++ K++ G + + Q+ + ++L V T + L ++L
Sbjct: 927 SDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHVKLQIQIVPVMQLY 978
Query: 4601 V--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVGGAQGCGECVSKPC 4650
V P GLCG+YN DD K W++ C K
Sbjct: 979 VSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM---MSC----PKGN 1031
Query: 4651 PSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCP 4710
PS C ++E F CG++ + GPLA CH +V P Y + C C + LC
Sbjct: 1032 PSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCT 1090
Query: 4711 AVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPE---GCES 4767
+ YV AC + W R C CP+ ++ +C SC SLS + E
Sbjct: 1091 ILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVED 1149
Query: 4768 ACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPEC---ERRCECGPG 4822
+GC C DA + + CV QC C Y EV PG + +C C G
Sbjct: 1150 VPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLIHIDDNKCVCRDG 1202
Score = 131 bits (330), Expect = 2e-29
Identities = 136/590 (23%), Positives = 224/590 (37%), Gaps = 80/590 (13%)
Query: 648 LCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV 707
+CEDG Q+ C ++E CG + L + + C+ + C
Sbjct: 681 VCEDGIQH----CNKIIGTYFEK---CGKVAALSNDYKMI------------CIDEYCQT 721
Query: 708 GGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPACPTSCN 763
++ S C S ++ C G + WRS ++ CP Y+ CGP+ P +C+
Sbjct: 722 R-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCS 780
Query: 764 GAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQEVWADEL 819
A + CV GC C G+ + G CV + C C G PG+ +
Sbjct: 781 NVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--REGP 835
Query: 820 CQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRR 879
C +CTC A T + CP RC V+ L +FDG +
Sbjct: 836 CGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------TTFDGVK 872
Query: 880 FDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYP 939
++F G C +L V + ++ ++ + G+ S T + K +
Sbjct: 873 YNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSD-- 928
Query: 940 GQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDF--GLTVTYDWNARVTAKVPSSYA 996
+ +D ++ + +D ++Q+F + V T F L + ++ +P +
Sbjct: 929 -GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQF 986
Query: 997 EALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVA 1056
GLCG++N DD + AF NSW+ C P C ++
Sbjct: 987 TDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE---MMSCPKGNPSSCISIE---- 1039
Query: 1057 QQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1116
++ ++ CGIL D GP CH ++P+ +C C LC L Y AC
Sbjct: 1040 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 1099
Query: 1117 QAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CHEGCVCD 1173
+ WR+ LC SCP ++ C SC L C E +GC C
Sbjct: 1100 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 1158
Query: 1174 EGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1222
+ + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1159 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHID---DNKCVCRDGILL 1205
Score = 127 bits (319), Expect = 3e-28
Identities = 126/506 (24%), Positives = 199/506 (39%), Gaps = 87/506 (17%)
Query: 1982 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 2041
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 2042 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEY-LLSA 2100
CT Q+ CQ + C +G+ H T DG ++F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 2101 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 2158
C G EN T + E ++ +R + + + ++ L +V V
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDG-----KVTAVKS 1396
Query: 2159 TLPFQLDSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYN 2215
T + + +A H G +++ +G+ + +D ++ + + + + G +CGLCGN N
Sbjct: 1397 TESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNN 1456
Query: 2216 QDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVI 2269
D DD A G G +Q C + V++ PC C ++
Sbjct: 1457 GDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRKCEIL 1514
Query: 2270 SATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQLREW 2327
D CH V P+ Y C+ + AC ++G G C AVA Y AC A G + W
Sbjct: 1515 --RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SW 1571
Query: 2328 RRPDFCPFQCPAHS-------HYELCGDSCPGSCPS-------LSAPEGCESACREGCVC 2373
R+P+ CP C ++ HYE CG +C S EGC + C
Sbjct: 1572 RKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP----- 1626
Query: 2374 DAGFVLSGDT--CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCG 2431
D+ L +T CV + +C C ++D P G C C C G++ C ++
Sbjct: 1627 DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSETA-- 1680
Query: 2432 PHETCRPSGGSLGCVAVGSTTCQASG 2457
P+ + +TT ++G
Sbjct: 1681 ------PTNSTFAVSTTTATTILSTG 1700
Score = 127 bits (319), Expect = 3e-28
Identities = 124/482 (25%), Positives = 191/482 (39%), Gaps = 87/482 (18%)
Query: 4384 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 4443
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 4444 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSA 4502
CT Q+ CQ + C +G+ H T DG + F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 4503 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 4560
C G EN T + E ++ +R + + + ++ L DG
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQ---------DGKVT 1392
Query: 4561 ALPF------QLDSLLHA-HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLC 4613
A+ +L++ ++ H G +++ +G+ + +D ++ + + + + +CGLC
Sbjct: 1393 AVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLC 1452
Query: 4614 GNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDA 4667
GN N D DD A G G +Q C + V++ PC
Sbjct: 1453 GNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRK 1510
Query: 4668 CGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQ 4725
C ++ D CH V P+ Y C+ + AC ++G G C AVA Y AC A G
Sbjct: 1511 CEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVC 1568
Query: 4726 LGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS-------LSAPEGCESACRE 4771
+ WR+P+ CP+ C ++ HYE CG +C S EGC + C
Sbjct: 1569 V-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP- 1626
Query: 4772 GCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQE 4829
D+ L +T CV + +C C ++ P G V C R C C G + C E
Sbjct: 1627 ----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSE 1678
Query: 4830 GA 4831
A
Sbjct: 1679 TA 1680
Score = 127 bits (318), Expect = 4e-28
Identities = 126/506 (24%), Positives = 198/506 (39%), Gaps = 87/506 (17%)
Query: 3183 PCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSL 3242
PC GC C G V ++ N C C G ++ GS C++ C C G S
Sbjct: 1252 PCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSV--TSVGCNE-CTCIKGSWS- 1307
Query: 3243 VCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEY-LLSA 3301
CT Q+ CQ + C +G+ H T DG + F G C+Y L
Sbjct: 1308 -CT----------------QNECQTI----CHIYGEGHVRTFDGKSYSFDGLCQYSFLED 1346
Query: 3302 PCHGPPLGAENFTVTVANEHRG--SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFV 3359
C G EN T + E ++ +R + + + ++ L +V V
Sbjct: 1347 YC-----GHENGTFRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDG-----KVTAVKS 1396
Query: 3360 TLPFQLDSLLHA---HLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYN 3416
T + + +A H G +++ +G+ + +D ++ + + + + G +CGLCGN N
Sbjct: 1397 TESKKCELNANAYSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNN 1456
Query: 3417 QDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVI 3470
D DD A G G +Q C + V++ PC C ++
Sbjct: 1457 GDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFPCDSNPYCKAWAVRKCEIL 1514
Query: 3471 SATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPAVATYVAACQAAGAQLREW 3528
D CH V P+ Y C+ + AC ++G G C AVA Y AC A G + W
Sbjct: 1515 --RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAMYAEACSAVGVCV-SW 1571
Query: 3529 RRPDFCPFQCPAHS-------HYELCGDSCPGSCPS-------LSAPEGCESACREGCVC 3574
R+P+ CP C ++ HYE CG +C S EGC + C
Sbjct: 1572 RKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCP----- 1626
Query: 3575 DAGFVLSGDT--CVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCG 3632
D+ L +T CV + +C C ++D P G C C C G++ C ++
Sbjct: 1627 DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGRTCYC-IAGQLECSETA-- 1680
Query: 3633 PHETCRPSGGSLGCVAVGSTTCQASG 3658
P+ + +TT ++G
Sbjct: 1681 ------PTNSTFAVSTTTATTILSTG 1700
Score = 125 bits (315), Expect = 9e-28
Identities = 131/545 (24%), Positives = 193/545 (35%), Gaps = 80/545 (14%)
Query: 4694 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCG 4749
C+ + CQ + C + C + G E R D C Q CP Y+ CG
Sbjct: 714 CIDEYCQTRDKTS-TCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECG 772
Query: 4750 DSCPVSCPSLSAPEGCESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGE 4805
S P +C +++ + +S C GC C G++L CV +C C G Y GE
Sbjct: 773 PSNPATCSNVAPFQ--DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE 830
Query: 4806 VFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHY 4864
V R CG +C +D +C C GRC G
Sbjct: 831 V--------REGPCG----------------SQCTCQDAKWSCTEALCPGRCKVEGS-SL 865
Query: 4865 ITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQG 4924
T DG Y+ G+C ++ +ED+SI +E Q V+L
Sbjct: 866 TTFDGVKYNFPGNCHFLAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLN 915
Query: 4925 QQVTVDGEAVALPVAVGRVRVTAEG------------RNMVLQTTK----GLRLLFDGDA 4968
V VD V ++ +G + LQ L++
Sbjct: 916 SSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 4969 HLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGC 5028
L +S+P GLCG++N DDF+ + + F +W KG
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG----- 1030
Query: 5029 GPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKA 5088
P C E+ A CG L + GP A+C +++P Y +C C + +
Sbjct: 1031 NPSSCISIEKEKFA----ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 5089 FLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGC 5147
LC L Y AC + WRT C CP+ + + C SC +LS C
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 5148 TTR--CFEGCECDD-RFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSS 5204
+GC C D + ++G C+ C C N + + D +C C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHIDD--NKCVCRDGI 1203
Query: 5205 GLTCQ 5209
L CQ
Sbjct: 1204 -LLCQ 1207
Score = 115 bits (289), Expect = 9e-25
Identities = 144/607 (23%), Positives = 225/607 (37%), Gaps = 120/607 (19%)
Query: 2660 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 2718
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 2719 QVEPWRNET--FCPME-CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLY 2775
E WR+++ C + CP+ Y+ C + CS + AP Q + C GC C G+L
Sbjct: 745 TFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNV-APFQDSE-CVSGCTCPEGYLL 802
Query: 2776 NGQA----CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVC 2831
+ CV +C C +G Y+P + V C QCTC K C E C PG+
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS-CTEALC-PGR-- 857
Query: 2832 QPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 2891
CK +G +FDG K++
Sbjct: 858 -------------------------CKVEGSS------------------LTTFDGVKYN 874
Query: 2892 FQGTCNYV----------LATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 2941
F G C+++ + CP S Q T T N P YV
Sbjct: 875 FPGNCHFLAVHNEDWSISVELRPCP--SGQTGTCLNSVTLLLNSSVPVDKYV-------F 925
Query: 2942 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNW 2998
++ ++ D K+R G + +I + +S L V + LQ+
Sbjct: 926 NSDGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 2999 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 3058
++ V++P + GLCG+ + +D + L + + SW C
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGN 1031
Query: 3059 RGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 3118
SC + +++ + CG L +G P +CH V P+ + + C C +D
Sbjct: 1032 PSSCISIEKEKFAERH----CGILLDSSG-PLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 3119 ILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPA 3178
LC L +YV AC I WR + CE +CP ++ C +SC S +
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 3179 VCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 3237
E V+GC C DA + + CV L + C C+ N + G D +C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHIDDN-----KCVC 1199
Query: 3238 GGGSLVC 3244
G L+C
Sbjct: 1200 RDGILLC 1206
Score = 115 bits (288), Expect = 1e-24
Identities = 143/605 (23%), Positives = 225/605 (37%), Gaps = 116/605 (19%)
Query: 3861 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 3919
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 3920 HVEPWRNET--FCPME-CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLY 3976
E WR+++ C + CP+ Y+ C + CS + AP Q + C GC C G+L
Sbjct: 745 TFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNV-APFQDSE-CVSGCTCPEGYLL 802
Query: 3977 NGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVC 4032
+ CV +C C +G Y+P + V C QCTC K C E C PG+
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS-CTEALC-PGR-- 857
Query: 4033 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 4092
CK +G +FDG K++
Sbjct: 858 -------------------------CKVEGSS------------------LTTFDGVKYN 874
Query: 4093 FQGTCNYV--------LATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGT 4144
F G C+++ ++ P S Q T T N P YV +
Sbjct: 875 FPGNCHFLAVHNEDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYV-------FNS 927
Query: 4145 NISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADF---GLQVSYDWNWRV 4201
+ ++ D K+R G + +I + +S L V + LQ+ ++
Sbjct: 928 DGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQVETYFHVKLQIQIVPVMQL 977
Query: 4202 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 4261
V++P + GLCG+ + +D + L + + SW C
Sbjct: 978 YVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGNPS 1033
Query: 4262 SCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL 4321
SC + +++ + CG L + GP +CH V P+ + + C C +D L
Sbjct: 1034 SCISIEKEKFAERH----CGILLD-SSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCL 1088
Query: 4322 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVC 4381
C L +YV AC I WR + CE +CP ++ C +SC S +
Sbjct: 1089 CTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDV 1147
Query: 4382 EGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGG 4440
E V+GC C DA + + CV L + C C+ N + G D +C
Sbjct: 1148 EDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHIDDN-----KCVCRD 1201
Query: 4441 GSLVC 4445
G L+C
Sbjct: 1202 GILLC 1206
Score = 114 bits (286), Expect = 2e-24
Identities = 142/607 (23%), Positives = 222/607 (36%), Gaps = 120/607 (19%)
Query: 1459 EFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAG-G 1517
E CG +++ LS+ +K++ CI + C S C C + G G
Sbjct: 698 EKCGKVAA----LSNDYKMI--------CIDEYCQTRDKTST-CDTYSELSRLCASDGPG 744
Query: 1518 HVEPWRTET--FCPME-CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLY 1574
E WR+++ C + CP Y+ C + CS ++ P C GC C G+L
Sbjct: 745 TFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATCSNVA--PFQDSECVSGCTCPEGYLL 802
Query: 1575 NGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVC 1630
+ CV +C C +G Y+P + V C QCTC K C E C PG+
Sbjct: 803 DDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS-CTEALC-PGR-- 857
Query: 1631 QPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFD 1690
CK +G +FDG K++
Sbjct: 858 -------------------------CKVEGSS------------------LTTFDGVKYN 874
Query: 1691 FQGTCNYV----------LATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAAL 1740
F G C+++ + CP S Q T T N P YV
Sbjct: 875 FPGNCHFLAVHNEDWSISVELRPCP--SGQTGTCLNSVTLLLNSSVPVDKYV-------F 925
Query: 1741 GTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF---GLQVSYDWNW 1797
++ ++ D K+R G + +I + +S L V + LQ+
Sbjct: 926 NSDGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQVETYFHVKLQIQIVPVM 975
Query: 1798 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 1857
++ V++P + GLCG+ + +D + L + + SW C
Sbjct: 976 QLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS----CPKGN 1031
Query: 1858 RGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRD 1917
SC + +++ + CG L +G P +CH V P+ + + C C +D
Sbjct: 1032 PSSCISIEKEKFAERH----CGILLDSSG-PLASCHPIVNPKPYHEECKKYTCTCENSQD 1086
Query: 1918 ILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPA 1977
LC L +YV AC I WR + CE +CP ++ C +SC S +
Sbjct: 1087 CLCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNSSCRSLSERDRSC 1145
Query: 1978 VCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 2036
E V+GC C DA + + CV L + C C+ N + G D +C
Sbjct: 1146 DVEDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHIDDN-----KCVC 1199
Query: 2037 GGGSLVC 2043
G L+C
Sbjct: 1200 RDGILLC 1206
Score = 61.2 bits (147), Expect = 3e-08
Identities = 52/200 (26%), Positives = 83/200 (41%), Gaps = 33/200 (16%)
Query: 5060 FATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--F 5116
F C V + S ++ D Q DK C + + + C + G + WR+DS
Sbjct: 697 FEKCGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVV 756
Query: 5117 CPLH-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPV 5171
C CP Y C + +C+ ++ + C GC C + +LL +G C+
Sbjct: 757 CGTQRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLK 814
Query: 5172 QDCGCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWA 5230
+C C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 815 AECPCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE-------- 861
Query: 5231 TRGLCVLSVGANLTTFDGAR 5250
G++LTTFDG +
Sbjct: 862 ---------GSSLTTFDGVK 872
Score = 60.1 bits (144), Expect = 6e-08
Identities = 58/235 (24%), Positives = 97/235 (41%), Gaps = 26/235 (11%)
Query: 5151 CFEGCECDDRFLL-SQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 5209
C GC C + + S+G+C+ DC C+ GR S+ + C+E C+C S +C
Sbjct: 1253 CKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYD-EGSVTSVGCNE-CTCIKGSW-SCT 1309
Query: 5210 AAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQ 5269
C +C + E ++ TFDG + Y G +
Sbjct: 1310 QNECQT--ICHIYGEG----------------HVRTFDGKSYSFDGLCQYSFLEDYCGHE 1351
Query: 5270 NTIPWYRVVAE-VQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASV 5328
N +R++ E V C ++ + FQD + L K V E A+
Sbjct: 1352 NGT--FRILTESVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTE-SKKCELNANA 1408
Query: 5329 SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
T L+++ + G+ V N +++VI+ + GK+CG CGN +GD +D+
Sbjct: 1409 YSIHTVGLYLILKFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDF 1463
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 228 bits (582), Expect = 1e-58
Identities = 218/797 (27%), Positives = 313/797 (39%), Gaps = 119/797 (14%)
Query: 1329 VTVNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMC 1387
V +N + + LP V A+ + R S + V + L+V V + VT+ Q+
Sbjct: 367 VLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
Query: 1388 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKC 1447
GLCGN+NG DDF+ +G F N+W+ L P C
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDP-----------C 475
Query: 1448 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 1507
+E E +C LL P CH VDP K C +D C N LC+ + +
Sbjct: 476 SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSS 535
Query: 1508 YVSACQAAGGHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALS-APPQCQDGCA 1563
Y AC A G + WR E C + CP + + TC C +LS A C +G A
Sbjct: 536 YARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFA 594
Query: 1564 --EGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGK----- 1615
+GC C D FL CVP+ +C CYH G+Y E V+ ++C C G+
Sbjct: 595 PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRDGRLHCRQ 652
Query: 1616 -----------------------------GMVCQ-------EHSCKPGQVCQPSG----G 1635
+ CQ C G VC P G G
Sbjct: 653 IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDG 711
Query: 1636 ILSCVTKDPC----------HGVTCRPQ-ETCKEQGGQGVCLPNY-EATCWLWGDPHYHS 1683
CV + C G + TC + G+ VC TC ++G HY +
Sbjct: 712 RGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYIT 771
Query: 1684 FDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 1743
FDG+ +DF G C+YV C S+ G F++ T+N G V+ + + + T
Sbjct: 772 FDGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTE 829
Query: 1744 ISIH-KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV-ADFGLQVSYDWNWRVDV 1801
+ + K + R G A T+ + L+V + G+ V +D V +
Sbjct: 830 LKLEDKHRVVIQRDEGHHVAY----------TTREVGQYLVVESSTGIIVIWDKRTTVFI 879
Query: 1802 TLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSC 1861
L SY G VCGLCGN D NND + + S +G SW+ P C D
Sbjct: 880 KLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNPE 936
Query: 1862 PTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDIL 1919
P C + + C L F+ CH+ V P+ F++ CV D C GGD +
Sbjct: 937 P-CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCECF 992
Query: 1920 CKALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGSPCPASCPSPAP 1972
C A+ASY C G + WR C I C + HYE CG+ +C +
Sbjct: 993 CSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTING 1051
Query: 1973 L---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTC 2028
+ + + EG C C D + +CV + CGC+ T++ G+ + TC
Sbjct: 1052 IHSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEETC 1109
Query: 2029 SQWCRCGPGGGSLVCTP 2045
C C +VC P
Sbjct: 1110 KS-CVC-TNSSQVVCRP 1124
Score = 228 bits (580), Expect = 2e-58
Identities = 218/796 (27%), Positives = 313/796 (39%), Gaps = 117/796 (14%)
Query: 3731 VTVNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMC 3789
V +N + + LP V A+ + R S + V + L+V V + VT+ +
Sbjct: 367 VLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
Query: 3790 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKC 3849
GLCGN+NG DDF+ +G F N+W+ S C D C
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA---QSSCHDKLDWL--------DDPC 475
Query: 3850 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 3909
+E E +C LL P CH VDP K C +D C N LC+ + +
Sbjct: 476 SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSS 535
Query: 3910 YVSACQAAGGHVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALS-APLQCPDGCA 3965
Y AC A G + WR E C + CP + + TC C +LS A C +G A
Sbjct: 536 YARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFA 594
Query: 3966 --EGCQC-DSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKV---- 4018
+GC C D FL CVP+ +C CYH G+Y E V+ ++C C G++
Sbjct: 595 PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRDGRLHCRQ 652
Query: 4019 ------------------------------VVCQ-------EHSCKPGQVCQPSG----G 4037
+ CQ C G VC P G G
Sbjct: 653 IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVC-PDGLMDDG 711
Query: 4038 ILSCVTKDPC----------HGVTCRPQ-ETCKEQGGQGVCLPNY-EATCWLWGDPHYHS 4085
CV + C G + TC + G+ VC TC ++G HY +
Sbjct: 712 RGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYIT 771
Query: 4086 FDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTN 4145
FDG+ +DF G C+YV C S+ G F++ T+N G V+ + + + T
Sbjct: 772 FDGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTE 829
Query: 4146 ISIH-KDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVT 4204
+ + K + R G A G+ V + ++ G+ V +D V +
Sbjct: 830 LKLEDKHRVVIQRDEGHHVAYTTREV-GQYLVVESST--------GIIVIWDKRTTVFIK 880
Query: 4205 LPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP 4264
L SY G VCGLCGN D NND + + S +G SW+ P C D P
Sbjct: 881 LAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNPEP 937
Query: 4265 TCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILC 4322
C + + C L S F+ CH+ V P+ F++ CV D C GGD + C
Sbjct: 938 -CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFC 993
Query: 4323 KALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSPAPL 4375
A+ASY C G + WR C I C + HYE CG +C + +
Sbjct: 994 SAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGI 1052
Query: 4376 ---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 4431
+ + EG C C D + +CV + CGC+ T++ G+ + TC
Sbjct: 1053 HSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEETCK 1110
Query: 4432 QWCRCGPGGGSLVCTP 4447
C C +VC P
Sbjct: 1111 S-CVC-TNSSQVVCRP 1124
Score = 224 bits (570), Expect = 2e-57
Identities = 213/796 (26%), Positives = 314/796 (39%), Gaps = 117/796 (14%)
Query: 2530 VTVNGVDMKLPVVLANGQI-RASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMC 2588
V +N + + LP V A+ + R S + V + L+V V + VT+ +
Sbjct: 367 VLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQ 426
Query: 2589 GLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEEC 2648
GLCGN+NG DDF+ +G F N+W+ +C + + C
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKA---------QSSCHDKLDWL--DDPC 475
Query: 2649 PPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHA 2708
+E E +C LL P CH VDP K C +D C N LC+ + +
Sbjct: 476 SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSS 535
Query: 2709 YVSACQAAGGQVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALS-APLQCPDGCA 2764
Y AC A G + WR E C + CP + + TC C +LS A C +G A
Sbjct: 536 YARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADSHCLEGFA 594
Query: 2765 --EGCQC-DSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKV---- 2817
+GC C D FL CVP+ +C CYH G Y E V+ ++C C G++
Sbjct: 595 PVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRDGRLHCRQ 652
Query: 2818 ------------------------------VVCQ-------EHSCKPGQVCQPS------ 2834
+ CQ C G VC
Sbjct: 653 IRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGR 712
Query: 2835 GGIL-----SCVNKDPCHGVTCRPQ---ETCKEQGGQGVCLPNY-EATCWLWGDPHYHSF 2885
GG + CV+ + + + + TC + G+ VC TC ++G HY +F
Sbjct: 713 GGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITF 772
Query: 2886 DGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNI 2945
DG+ +DF G C+YV C S+ G F++ T+N G V+ + + + T +
Sbjct: 773 DGKYYDFDGHCSYVAVQDYCGQNSSLG--SFSIITENVPCGTTGVTCSKAIKIFMGRTEL 830
Query: 2946 SIH-KDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLV-ADFGLQVSYDWNWRVDVT 3003
+ K + R G A T+ + L+V + G+ V +D V +
Sbjct: 831 KLEDKHRVVIQRDEGHHVAY----------TTREVGQYLVVESSTGIIVIWDKRTTVFIK 880
Query: 3004 LPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP 3063
L SY G VCGLCGN D NND + + S +G SW+ P C D P
Sbjct: 881 LAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---PTCPDVSTNPEP 937
Query: 3064 TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM--GGGDRDILC 3121
C + + C L F+ CH+ V P+ F++ CV D C GGD + C
Sbjct: 938 -CSLNPHRRSWAEKQCSILKSSV---FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFC 993
Query: 3122 KALASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSPAPL 3174
A+ASY C G + WR C I C + HYE CG +C + +
Sbjct: 994 SAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGI 1052
Query: 3175 ---TTPAVCEGPCVEGCQCDAG-FVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCS 3230
+ + EG C C D + +CV + CGC+ T++ G+ + TC
Sbjct: 1053 HSNISVSYLEG-CYPRCPKDRPIYEEDLKKCVTADK-CGCYVEDTHYPPGASVPTEETCK 1110
Query: 3231 QWCRCGPGGGSLVCTP 3246
C C +VC P
Sbjct: 1111 S-CVC-TNSSQVVCRP 1124
Score = 205 bits (522), Expect = 9e-52
Identities = 181/720 (25%), Positives = 278/720 (38%), Gaps = 144/720 (20%)
Query: 4611 GLCGNYNQDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGP 4665
GLCGN+N DD K G G A + C K PC+ + +
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAE 486
Query: 4666 DACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQ 4725
C ++ T+ P CH V PA+Y++ C D C Q + LC A+++Y AC A G
Sbjct: 487 HWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVM 546
Query: 4726 LGEWRRPDFCPL---QCPAHSHYELCGDSCPVSCPSLSAPEGCESACRE------GCVC- 4775
L WR C CP + +C +C SLS +S C E GC C
Sbjct: 547 LWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCP 602
Query: 4776 DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPG------------- 4822
D F+ CVP+ +C C H G Y G+V E RC C G
Sbjct: 603 DHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVV---RQEERCVCRDGRLHCRQIRLIGQS 659
Query: 4823 ---------------------GHVTCQEGAACGPHEEC---------RLEDGVQAC---- 4848
++CQ AA H EC ++DG C
Sbjct: 660 CTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRGGCVVEK 719
Query: 4849 ----------HATG------CGRCLANGGI------------------HYITLDGRVYDL 4874
+++G C C G HYIT DG+ YD
Sbjct: 720 ECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDF 779
Query: 4875 HGSCSYVLAQ-VCHPKPGDEDFSIVLEKNAAGDL-----QRLLVTVAGQVVSLAQGQQVT 4928
G CSYV Q C FSI+ E G + + + + + L +V
Sbjct: 780 DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
Query: 4929 V---DGEAVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCG 4984
+ +G VA T E G+ +V++++ G+ +++D + + + ++G +CG
Sbjct: 840 IQRDEGHHVAY--------TTREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCG 891
Query: 4985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPY 5044
LCGNF+ ++DF + SS FG +W+ + P C
Sbjct: 892 LCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP-----CSLNPHRRS 946
Query: 5045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLAAYTAACQ 5102
+ + C L++ F+ C + + P ++ CV+D C+ GD C ++A+Y C
Sbjct: 947 WAEKQCSILKS--SVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECT 1004
Query: 5103 AAGVAVKPWRTDSFCPLHC----PAHS---HYSICTRTCQGSCAALSGL-TGCTTRCFEG 5154
G V WRT CP+ C P H HY C +C ++G+ + + EG
Sbjct: 1005 KEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEG 1063
Query: 5155 C--EC-DDRFLLSQGV--CIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 5209
C C DR + + + C+ CGC + P +S+ T + + C C++SS + C+
Sbjct: 1064 CYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNSSQVVCR 1123
Score = 180 bits (456), Expect = 4e-44
Identities = 137/466 (29%), Positives = 206/466 (44%), Gaps = 57/466 (12%)
Query: 776 CVEGCVCLPGFVASG-GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVT 834
CV GCVC G + G G CV C C + G ++ D CN T
Sbjct: 697 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--------CN------T 742
Query: 835 CRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS- 893
C +C G Q C+ GTC G HY++FDG+ +DF G C+Y+ V
Sbjct: 743 C----TCKRGRWVCTQ---AVCH----GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
Query: 894 CGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPF 953
CGQN++L +F ++ EN G+ V+ ++A+++ ++ + ++ V+ D ++ +
Sbjct: 792 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHR-VVIQRDEGHHVAY 850
Query: 954 QAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADD 1013
+ G+ VV + G+ V +D V K+ SY +CGLCGNF+ +D
Sbjct: 851 TTRE-------VGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
Query: 1014 LALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKG 1073
R ++ L FGNSW+E +T P C ++ ++ +C IL
Sbjct: 904 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPH---RRSWAEKQCSIL--KSS 958
Query: 1074 PFRECHSKLDPQGAVRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEEL 1131
F CHSK+DP+ CV+D C G C A+A+YA C GA V WR+ +L
Sbjct: 959 VFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDL 1017
Query: 1132 CPLSC----PPHS---HYEACSYGCPLSCGDL-PVPGGCGSECHEGCV--CDEGFALSGE 1181
CP+ C PPH HYE C +C + + EGC C + + E
Sbjct: 1018 CPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEE 1077
Query: 1182 ---SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224
C+ CGC + T++PPG + C S C C V C
Sbjct: 1078 DLKKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVC 1122
Score = 177 bits (448), Expect = 3e-43
Identities = 156/597 (26%), Positives = 228/597 (38%), Gaps = 102/597 (17%)
Query: 2353 SCPSLSAPEGCESACREGCVCDAGFVLSG-DTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
SC +L+A + C GCVC G + G CV +C C+H++ Y G C
Sbjct: 684 SCQTLAAGY-YHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--C 740
Query: 2412 DSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDF 2471
++ C C+ G V + AV TC G HY TFDG+ +DF
Sbjct: 741 NT-CTCKRGRWVCTQ--------------------AVCHGTCSIYGSGHYITFDGKYYDF 779
Query: 2472 MGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV 2530
G C YV Q CG L F+++ ENV G V+ ++ I + + L+LE + V
Sbjct: 780 DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
Query: 2531 TVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGL 2590
D V ++ G +V+E+ G+ V +D V + + +Y +CGL
Sbjct: 840 IQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGL 892
Query: 2591 CGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPP 2650
CGN++ +DF + + +FGNSW+E PTCP S E C
Sbjct: 893 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---------PTCPDVSTN---PEPCSL 940
Query: 2651 ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHA 2708
++ E+ C +L S S CH VDP+ + C+ D C GG+ CS + +
Sbjct: 941 NPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVAS 998
Query: 2709 YVSACQAAGGQVEPWRNETFCPMECPQNS-------HYELCADTCSLGCSALSA-----P 2756
Y C G V WR CP+ C + HYE C + C ++
Sbjct: 999 YAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057
Query: 2757 LQCPDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVG 2815
+ +GC C D + CV +CGCY +Y P +V + + C C
Sbjct: 1058 VSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNS 1117
Query: 2816 KVVVCQEHSCK-----------PGQVCQPSGGILSCVNKDPCHGVTCRPQ---------- 2854
VVC+ K ++C P+G + N +T RP
Sbjct: 1118 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFN---ICSITTRPSTLTTFTTITL 1174
Query: 2855 ---------ETCKEQGGQGVCLPNYEATCWLWGD------PHYHSFDGRKFDFQGTC 2896
T L C LW D P S DG + F G C
Sbjct: 1175 PTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVC 1231
Score = 176 bits (447), Expect = 4e-43
Identities = 173/675 (25%), Positives = 248/675 (36%), Gaps = 105/675 (15%)
Query: 1079 HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP- 1137
H+ LD +G C G D + C +H R L SC
Sbjct: 604 HTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQEERCVCRDGRLH-CRQIRLIGQSCTA 662
Query: 1138 PHSHYE-------ACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGES-CLPLASC 1189
P H + A S LSC L G +EC GCVC +G G C+ C
Sbjct: 663 PKIHMDCSNLTALATSKPRALSCQTLAA-GYYHTECVSGCVCPDGLMDDGRGGCVVEKEC 721
Query: 1190 GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGS 1249
CVH + G C++ C C+ G V + AV
Sbjct: 722 PCVHNNDLYSSGAKIKVD--CNT-CTCKRGRWVCTQ--------------------AVCH 758
Query: 1250 STCQASGDPHYTTFDGRRFDFMGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVT 1308
TC G HY TFDG+ +DF G C YV Q CG L F+++ ENV G V+ +
Sbjct: 759 GTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCS 818
Query: 1309 RVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAY 1368
+ I + + L+LE + V D V ++ G +V+E+ G+ V +
Sbjct: 819 KAIKIFMGRTELKLEDKHRVVIQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIW 871
Query: 1369 DLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 1428
D V + + +Y +CGLCGN++ +DF + + +FGNSW+E P P
Sbjct: 872 DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKE-APTCPD 930
Query: 1429 LPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 1488
+ P P C ++ E+ C +L S S CH VDP+ + C+
Sbjct: 931 VSTNPEP-----------CSLNPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACV 977
Query: 1489 FDLCL--GGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMEC----PPNS---HYE 1539
D C GG+ CS + +Y C G V WRT CP+ C PP+ HYE
Sbjct: 978 HDSCSCDTGGDCECFCSAVASYAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYE 1036
Query: 1540 LCADTCSLGCSALSA-----PPQCQDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVY 1593
C + C ++ +GC C D + CV +CGCY +
Sbjct: 1037 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH 1096
Query: 1594 YEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCK-----------PGQVCQPSGGI-----L 1637
Y P +V + + C C +VC+ K ++C P+G + +
Sbjct: 1097 YPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNI 1156
Query: 1638 SCVTKDPCHGVTCR-----------PQETCKEQGGQGVCLPNYEATCWLWGD------PH 1680
+T P T T L C LW D P
Sbjct: 1157 CSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPS 1216
Query: 1681 YHSFDGRKFDFQGTC 1695
S DG + F G C
Sbjct: 1217 SGSDDGDRETFDGVC 1231
Score = 174 bits (441), Expect = 2e-42
Identities = 155/594 (26%), Positives = 227/594 (38%), Gaps = 96/594 (16%)
Query: 3554 SCPSLSAPEGCESACREGCVCDAGFVLSG-DTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 3612
SC +L+A + C GCVC G + G CV +C C+H++ Y G C
Sbjct: 684 SCQTLAAGY-YHTECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--C 740
Query: 3613 DSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDF 3672
++ C C+ G V + AV TC G HY TFDG +DF
Sbjct: 741 NT-CTCKRGRWVCTQ--------------------AVCHGTCSIYGSGHYITFDGKYYDF 779
Query: 3673 MGTCVYVLAQT-CGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV 3731
G C YV Q CG L F+++ ENV G V+ ++ I + + L+LE + V
Sbjct: 780 DGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVV 839
Query: 3732 TVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGL 3791
D V ++ G +V+E+ G+ V +D V + + +Y +CGL
Sbjct: 840 IQR--DEGHHVAYTTREV-----GQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGL 892
Query: 3792 CGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPP 3851
CGN++ +DF + + +FGNSW+E PTCP S P C
Sbjct: 893 CGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEA---------PTCPDVSTNPEP---CSL 940
Query: 3852 ELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL--GGGNLSILCSNIHA 3909
++ E+ C +L S S CH VDP+ + C+ D C GG+ CS + +
Sbjct: 941 NPHRRSWAEKQCSILKSSV--FSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVAS 998
Query: 3910 YVSACQAAGGHVEPWRNETFCPMECPQNS-------HYELCADTCSLGCSALSA-----P 3957
Y C G V WR CP+ C + HYE C + C ++
Sbjct: 999 YAQECTKEGACVF-WRTPDLCPIFCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNIS 1057
Query: 3958 LQCPDGCAEGCQCDSGFLYNG-QACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVG 4016
+ +GC C D + CV +CGCY +Y P +V + + C C
Sbjct: 1058 VSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVPTEETCKSCVCTNS 1117
Query: 4017 KVVVCQEHSCK-----------PGQVCQPSGGI-----LSCVTKDPCHGVTCR------- 4053
VVC+ K ++C P+G + + +T P T
Sbjct: 1118 SQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPSTLTTFTTITLPTT 1177
Query: 4054 ----PQETCKEQGGQGVCLPNYEATCWLWGD------PHYHSFDGRKFDFQGTC 4097
T L C LW D P S DG + F G C
Sbjct: 1178 PTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDRETFDGVC 1231
Score = 160 bits (404), Expect = 4e-38
Identities = 118/404 (29%), Positives = 178/404 (44%), Gaps = 39/404 (9%)
Query: 455 CQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVE-LCSEDDTLPAFS 512
C G+ C A C G HY TFDG+ YD G CSY V+ C ++ +L +FS
Sbjct: 743 CTCKRGRWVCTQAVCHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFS 802
Query: 513 VEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQ 572
+ +N G+ V+ S ++ + G L D + R+ + EG Y
Sbjct: 803 IITENVPCGTTGVTC---------SKAIKIFMGRTELKLED--KHRVVIQRDEGHHVAYT 851
Query: 573 S---GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGAL 629
+ G VVE G++V +D + + L ++ VCGLCGN++ +DF T D +
Sbjct: 852 TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMV 911
Query: 630 APDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHD 689
++F +SWK C D N P C+ + ++ C +L F++CH
Sbjct: 912 VSSELDFGNSWKEAP---TCPDVSTNPEP-CSLNPHRRSWAEKQCSILK--SSVFSICHS 965
Query: 690 TLDPRPFLEQCVYDLCV--VGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSC-- 745
+DP+PF E CV+D C GG+ C +++YAQ C + G V WR+P CP+ C
Sbjct: 966 KVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDY 1024
Query: 746 -----PANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCV--C---LPGFVASGGACVP 795
YE CG +C + +EGC C P + CV
Sbjct: 1025 YNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVT 1084
Query: 796 ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ 839
A CGC + PG V +E C + C C ++ QV CR ++
Sbjct: 1085 ADKCGCYVEDTHYPPGASVPTEETC-KSCVCTNSS-QVVCRPEE 1126
Score = 144 bits (364), Expect = 2e-33
Identities = 119/469 (25%), Positives = 188/469 (40%), Gaps = 65/469 (13%)
Query: 3184 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 3243
CV GC C G + + C C N + +G++ D C+ C C G V
Sbjct: 697 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWV 751
Query: 3244 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 3303
CT A C HG C +G HY+T DG +DF G C Y+
Sbjct: 752 CTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
Query: 3304 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVTLP 3362
G +F++ N G+ V+ ++++ + + L L + +Q D G V
Sbjct: 792 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT 851
Query: 3363 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADD 3422
G +VV +++G+ + +D + V +++ +Y G++CGLCGN++ +D
Sbjct: 852 --------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
Query: 3423 LKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLA 3478
++ E + P P PC+ C ++ ++ +
Sbjct: 904 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFS 961
Query: 3479 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPF 3536
CH V P +++ C+ D+C G C AVA+Y C GA + WR PD CP
Sbjct: 962 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPI 1020
Query: 3537 QC----PAHS---HYELCGDSCPGSCP---------SLSAPEGCESAC-REGCVCDAGFV 3579
C P H HYE CG+ +C S+S EGC C ++ + +
Sbjct: 1021 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL- 1079
Query: 3580 LSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEP 3628
CV +CGC +D +YP G + C S C C +V C P
Sbjct: 1080 ---KKCVTADKCGCYVEDTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1124
Score = 143 bits (361), Expect = 4e-33
Identities = 126/512 (24%), Positives = 203/512 (39%), Gaps = 71/512 (13%)
Query: 1944 VGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEG----PCVEGCQCDAGFVLSADR 1999
+G T P+ H + C + + P L+ + G CV GC C G +
Sbjct: 656 IGQSCTAPK-IHMD-CSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDGLMDDGRG 713
Query: 2000 CVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPS 2059
+ C C N + +G++ D C+ C C G VCT A C
Sbjct: 714 GCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWVCTQAVC----------- 757
Query: 2060 GQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANE 2119
HG C +G HY+T DG ++F G C Y+ G +F++ N
Sbjct: 758 --HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENV 808
Query: 2120 HRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVTLPFQLDSLLHAHLSGADVV 2178
G+ V+ ++++ + + L L + +Q D G V G +V
Sbjct: 809 PCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT--------TREVGQYLV 860
Query: 2179 VTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQ 2238
V +++G+ + +D + V +++ +Y G++CGLCGN++ +D ++
Sbjct: 861 VESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGN 920
Query: 2239 GCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLL 2294
E + P P PC+ C ++ ++ + CH V P +++ C+
Sbjct: 921 SWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFSICHSKVDPKPFYEACVH 978
Query: 2295 DACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQC----PAHS---HYEL 2345
D+C G C AVA+Y C GA + WR PD CP C P H HYE
Sbjct: 979 DSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWHYEP 1037
Query: 2346 CGDSCPGSCP---------SLSAPEGCESAC-REGCVCDAGFVLSGDTCVPVGQCGCLHD 2395
CG+ +C S+S EGC C ++ + + CV +CGC +
Sbjct: 1038 CGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL----KKCVTADKCGCYVE 1093
Query: 2396 DRYYPLGQTFYPGPGCDSLCRCREGGEVSCEP 2427
D +YP G + C S C C +V C P
Sbjct: 1094 DTHYPPGASVPTEETCKS-CVCTNSSQVVCRP 1124
Score = 139 bits (350), Expect = 8e-32
Identities = 121/484 (25%), Positives = 191/484 (39%), Gaps = 76/484 (15%)
Query: 4385 CVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV 4444
CV GC C G + + C C N + +G++ D C+ C C G V
Sbjct: 697 CVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVD--CNT-CTCKRG--RWV 751
Query: 4445 CTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPC 4504
CT A C HG C +G HY+T DG +DF G C Y+
Sbjct: 752 CTQAVC-------------HGT-------CSIYGSGHYITFDGKYYDFDGHCSYVAVQDY 791
Query: 4505 HGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVD-GVFVALP 4563
G +F++ N G+ V+ ++++ + + L L + +Q D G VA
Sbjct: 792 CGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYT 851
Query: 4564 FQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADD 4623
G +VV +++G+ + +D + V +++ +Y ++CGLCGN++ +D
Sbjct: 852 --------TREVGQYLVVESSTGIIVIWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNND 903
Query: 4624 LKAVGGKPAGWQVGGAQGCGECVSKP----CPSPCTPEQQESFGGPDACGVISATDGPLA 4679
++ E + P P PC+ C ++ ++ +
Sbjct: 904 FTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEPCSLNPHRRSWAEKQCSILKSS--VFS 961
Query: 4680 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL 4737
CH V P +++ C+ D+C G C AVA+Y C GA + WR PD CP+
Sbjct: 962 ICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVASYAQECTKEGACV-FWRTPDLCPI 1020
Query: 4738 QC----PAHS---HYELCGDSCPVSCP---------SLSAPEGCESAC-REGCVCDAGFV 4780
C P H HYE CG+ +C S+S EGC C ++ + +
Sbjct: 1021 FCDYYNPPHECEWHYEPCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDL- 1079
Query: 4781 LSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTC-----------QE 4829
CV +CGC + +YP G P E + C C V C Q+
Sbjct: 1080 ---KKCVTADKCGCYVEDTHYPPG-ASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQD 1135
Query: 4830 GAAC 4833
GA C
Sbjct: 1136 GAFC 1139
Score = 138 bits (348), Expect = 1e-31
Identities = 126/429 (29%), Positives = 188/429 (43%), Gaps = 37/429 (8%)
Query: 449 CAAGQRCQVVGGKAGCVA--ESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDD 506
C+ G + V GC E C GDPHY TFDG Y G C+Y +VE S
Sbjct: 1916 CSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--P 1973
Query: 507 TLPAFSVEAKNEH-RGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSE 565
++ F V N H + +VS + VR + V + + + V Q +R V+L
Sbjct: 1974 SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPY 2033
Query: 566 GR--LRVYQSGPRAVVEL-VFGLVVTYDWDCQLALSLP-ARFQDQVCGLCGNYNGDPADD 621
+ L VYQSG VV++ G++V+Y+ ++ LP RF + G CG +DD
Sbjct: 2034 KKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNTKGQCGTCTNTTSDD 2092
Query: 622 FLTPDGALAPDAVEFASSWKLDDGD--YLCEDGCQNNCPACT-PGQAQ---HYE--GDRL 673
+ P G + + A W ++D + PA T PG + H + L
Sbjct: 2093 CILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPL 2152
Query: 674 CGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVG 733
C ++ D FA CH + P+ + + CV+D C + G L C L AYA C + I +
Sbjct: 2153 CQLIK--DSLFAQCHALVPPQHYYDACVFDSCFMPGSSLE-CASLQAYAALCAQQNICL- 2208
Query: 734 DWRSPAN--CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFV-ASG 790
DWR+ + C + CP++ Y+ CGPA +C +++ N VEGC C G + +
Sbjct: 2209 DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN--NTVLVEGCFCPEGTMNYAP 2266
Query: 791 GACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQ 850
G V +CGC G P + E + C C + C+ K RCS Q
Sbjct: 2267 GFDVCVKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEGGSGIICQPK-------RCS-Q 2316
Query: 851 NGLLGCYPD 859
+ C D
Sbjct: 2317 KPVTHCVED 2325
Score = 135 bits (339), Expect = 1e-30
Identities = 127/510 (24%), Positives = 194/510 (38%), Gaps = 114/510 (22%)
Query: 4970 LLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCG 5029
L +++ +G++ GLCGNFNG DDF +G ++ F W+A S C +
Sbjct: 413 LFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS---CHDKLD 469
Query: 5030 PQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAF 5089
P L E+A Y + C L+ + PF C + + P+EY+++C YD C + ++
Sbjct: 470 WLDDPCSLNIESANY-AEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDC 528
Query: 5090 LCRSLAAYTAACQAAGVAVKPWRTDSFCPL---HCPAHSHYSICTRTCQGSCAALSGLTG 5146
LC +L++Y AC A GV + WR + C CP + TCQ +C +LS
Sbjct: 529 LCAALSSYARACTAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEADS 587
Query: 5147 CTTRCF---EGCECDDR-FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSC-- 5200
F +GC C D FL +G C+P+ C C H G YL ++ + ERC C
Sbjct: 588 HCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE--ERCVCRD 645
Query: 5201 --------------------------------SSSSGLTCQ--AAG-----CPPGRVC-- 5219
S L+CQ AAG C G VC
Sbjct: 646 GRLHCRQIRLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPD 705
Query: 5220 -----------------------------EVKAEARNCWATRG--LCVLSVGANLTTFDG 5248
++K + C RG +C +V + G
Sbjct: 706 GLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYG 765
Query: 5249 ARGATTSPG-VYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQD---GMVT 5304
+ T G Y+ C VA C G+ ++G I ++ G
Sbjct: 766 SGHYITFDGKYYDFDGHC----------SYVAVQDYC-GQNSSLGSFSIITENVPCGTTG 814
Query: 5305 LTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGS-----------LLVRQKAGVQVWLGAN 5353
+T +K + + R +L E V + R L+V G+ V
Sbjct: 815 VTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIWDKR 874
Query: 5354 GKVAVIVSNDHAGKLCGACGNFDGDQTNDW 5383
V + ++ + G +CG CGNFD ND+
Sbjct: 875 TTVFIKLAPSYKGTVCGLCGNFDHRSNNDF 904
Score = 132 bits (331), Expect = 1e-29
Identities = 128/486 (26%), Positives = 182/486 (37%), Gaps = 66/486 (13%)
Query: 4012 TCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNY 4071
TC V + C+P + S G+ +DP G C ++
Sbjct: 1894 TCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDP-----------------DGCCW-HW 1935
Query: 4072 EATCWL--WGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTV-TTKNQNRGN 4128
E C+ WGDPHY +FDG + +QG C YVL P V G+ N
Sbjct: 1936 ECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSC 1995
Query: 4129 PAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVAD 4188
P VR T L + + ++ +V+VN ALP G G + + + +
Sbjct: 1996 PRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAVALPYK-KYGLEVYQSGINYVVDIPE 2053
Query: 4189 FGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGS 4245
G+ VSY+ V LP YH G CG ++D + P+G + +
Sbjct: 2054 LGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQ 2110
Query: 4246 WRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGPGFCGPLSSGTGGP---------FTT 4293
W L D + CP + + G G P T P F
Sbjct: 2111 W-------LVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQ 2163
Query: 4294 CHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV--GCEIT 4351
CHA VPP+ ++ CV D C G + C +L +Y A C + + DWR C +
Sbjct: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALCAQQNICL-DWRNHTHGACLVE 2221
Query: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAG---FVLSADRCVPLNNG 4408
CP + Y+ CGP +C S + V VEGC C G + D CV
Sbjct: 2222 CPSHREYQACGPAEEPTCKSSSSQQNNTV----LVEGCFCPEGTMNYAPGFDVCV---KT 2274
Query: 4409 CGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQ 4467
CGC + E G F D C C C GG ++C P C V + G +
Sbjct: 2275 CGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLAT 2331
Query: 4468 PVSTAE 4473
V+ A+
Sbjct: 2332 EVNPAD 2337
Score = 130 bits (327), Expect = 4e-29
Identities = 123/451 (27%), Positives = 172/451 (38%), Gaps = 56/451 (12%)
Query: 2853 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 2903
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 1912 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
Query: 2904 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 2962
P V G+ N P VR T L + + ++ +V+VN
Sbjct: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 2029
Query: 2963 ALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 3019
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 2030 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 2085
Query: 3020 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGP 3076
++D + P+G + + W L D + CP + + G
Sbjct: 2086 TNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
Query: 3077 GFCGPLAPGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASY 3127
G P T P F CHA VPP+ ++ CV D C G + C +L +Y
Sbjct: 2139 GKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAY 2197
Query: 3128 VAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCV 3185
A C + + DWR C + CP + Y+ CGP +C S + V V
Sbjct: 2198 AALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LV 2252
Query: 3186 EGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGS 3241
EGC C G + D CV CGC + E G F D C C C GG
Sbjct: 2253 EGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSG 2306
Query: 3242 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 3272
++C P C V + G + V+ A+
Sbjct: 2307 IICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
Score = 128 bits (322), Expect = 1e-28
Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)
Query: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 1310
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
Query: 1311 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 1364
+ T +V T+ + Q +V VN + LP + Q G + V++ + G+
Sbjct: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 2056
Query: 1365 RVAYD-LVYYVRVTVP--GNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 1421
V+Y+ L + VR+ GN + CG C N DD P+G N + W
Sbjct: 2057 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 2113
Query: 1422 VVPDSPCLP--------PTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSS 1473
P P P P PG P C P C L+ +
Sbjct: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 2163
Query: 1474 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF--CPME 1531
CH LV PQ C+FD C G+ S+ C+++ AY + C A WR T C +E
Sbjct: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 2221
Query: 1532 CPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 1589
CP + Y+ C C + S+ Q EGC C G + Y V ++ CGC
Sbjct: 2222 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
Query: 1590 NGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 1645
+ V E + D C+ G G++CQ C KP C G L+ D C
Sbjct: 2281 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
Query: 1646 HGVTCRPQET--CKEQGGQGVCLPNYE 1670
+T T CKE+ VC +E
Sbjct: 2340 CNITVCKCNTSLCKEK--PSVCPLGFE 2364
Score = 127 bits (319), Expect = 3e-28
Identities = 122/451 (27%), Positives = 171/451 (37%), Gaps = 56/451 (12%)
Query: 1652 PQETCKEQGGQGVCLPNYEATCWLW---------GDPHYHSFDGRKFDFQGTCNYVLATT 1702
P TC G Q V + + + CW W GDPHY +FDG + +QG C YVL
Sbjct: 1912 PMPTCSN-GLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE 1970
Query: 1703 GCPGVSTQGLTPFTV-TTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLT 1761
P V G+ N P VR T L + + ++ +V+VN
Sbjct: 1971 ISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQV-QVQVNRQAV 2029
Query: 1762 ALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYH---GAVCGLCGNM 1818
ALP G G + + + + G+ VSY+ V LP YH G CG
Sbjct: 2030 ALPYK-KYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLP--YHRFGNNTKGQCGTC 2085
Query: 1819 DRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCP---TCPEDRLEQYEGP 1875
++D + P+G + + W L D + CP + + G
Sbjct: 2086 TNTTSDDCILPSGEIVSNCEAAADQW-------LVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
Query: 1876 GFCGPLAPGTGGP---------FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASY 1926
G P T P F CHA VPP+ ++ CV D C G + C +L +Y
Sbjct: 2139 GKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPGS-SLECASLQAY 2197
Query: 1927 VAACQAAGVVIEDWRAQV--GCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCV 1984
A C + + DWR C + CP + Y+ CG +C S + V V
Sbjct: 2198 AALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQNNTV----LV 2252
Query: 1985 EGCQCDAG---FVLSADRCVPLNNGCGC-WANGTYHEAGSEFWADGTCSQWCRCGPGGGS 2040
EGC C G + D CV CGC + E G F D C C C GG
Sbjct: 2253 EGCFCPEGTMNYAPGFDVCV---KTCGCVGPDNVPREFGEHFEFD--CKN-CVCLEGGSG 2306
Query: 2041 LVCTPASCGLGEVCGLLPSGQHGCQPVSTAE 2071
++C P C V + G + V+ A+
Sbjct: 2307 IICQPKRCSQKPVTHCVEDGTYLATEVNPAD 2337
Score = 127 bits (318), Expect = 4e-28
Identities = 126/446 (28%), Positives = 178/446 (39%), Gaps = 49/446 (10%)
Query: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 2511
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
Query: 2512 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 2565
+ T +V T+ + Q +V VN + LP + Q G + V++ + G+
Sbjct: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 2056
Query: 2566 RVAYD-LVYYVRVTVP--GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 2622
V+Y+ L + VR+ GN + CG C N DD P+G N + W
Sbjct: 2057 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 2113
Query: 2623 VVPDSPCLP--------PPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSS 2674
P P P P PG P ++C P C L+ +
Sbjct: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 2163
Query: 2675 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETF--CPME 2732
CH LV PQ C+FD C G+ S+ C+++ AY + C A WRN T C +E
Sbjct: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 2221
Query: 2733 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCYHN 2791
CP + Y+ C C + S+ Q EGC C G + Y V ++ CGC
Sbjct: 2222 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
Query: 2792 GAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGILSC-VN-KDPCH 2847
+C+ G ++CQ C KP C G L+ VN D C
Sbjct: 2281 DNVPREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTCC 2340
Query: 2848 GVTCRPQET--CKEQGGQGVCLPNYE 2871
+T T CKE+ VC +E
Sbjct: 2341 NITVCKCNTSLCKEK--PSVCPLGFE 2364
Score = 126 bits (317), Expect = 5e-28
Identities = 92/266 (34%), Positives = 123/266 (46%), Gaps = 31/266 (11%)
Query: 594 QLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKL-----DDGDYL 648
QL ++L Q QV GLCGN+NG DDF T G + FA++WK D D+L
Sbjct: 412 QLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWL 471
Query: 649 CEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG 708
+D C N + A+H+ C +L K + PF CH +DP + ++C YD C
Sbjct: 472 -DDPCSLNIESAN--YAEHW-----CSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQ 523
Query: 709 GERLSLCRGLSAYAQACLELGISVGDWRSPANCPL---SCPANSRYELCGPACPTSCNG- 764
LC LS+YA+AC G+ + WR C SCP + + C +C
Sbjct: 524 NNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTCRSL 582
Query: 765 AAAPSNC-SGRPCVEGCVCLP-GFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 822
+ A S+C G V+GC C F+ G CVP + C C +GL L G V E
Sbjct: 583 SEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQE---E 639
Query: 823 RCTC-NGATHQVTCRD----KQSCPA 843
RC C +G H CR QSC A
Sbjct: 640 RCVCRDGRLH---CRQIRLIGQSCTA 662
Score = 125 bits (315), Expect = 9e-28
Identities = 127/447 (28%), Positives = 178/447 (39%), Gaps = 51/447 (11%)
Query: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWG-NGRVSVTRV 3712
C GDPHY TFDG + + G C YVL + P + F V +N N +VS R
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS--PSVDNFGVYIDNYHCDPNDKVSCPRT 1998
Query: 3713 I-----TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIE-TDFGL 3766
+ T +V T+ + Q +V VN + LP + Q G + V++ + G+
Sbjct: 1999 LIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALP--YKKYGLEVYQSGINYVVDIPELGV 2056
Query: 3767 RVAYD-LVYYVRVTVP--GNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 3823
V+Y+ L + VR+ GN + CG C N DD P+G N + W
Sbjct: 2057 LVSYNGLSFSVRLPYHRFGNNTKGQCGTCTN---TTSDDCILPSGEIVSNCEAAADQWLV 2113
Query: 3824 VVPDSPCLP--------PPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSS 3875
P P P P PG P C P C L+ +
Sbjct: 2114 NDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTP--------SPLCQLIKDSL--FAQ 2163
Query: 3876 CHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETF--CPME 3933
CH LV PQ C+FD C G+ S+ C+++ AY + C A WRN T C +E
Sbjct: 2164 CHALVPPQHYYDACVFDSCFMPGS-SLECASLQAYAALC-AQQNICLDWRNHTHGACLVE 2221
Query: 3934 CPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCY-H 3991
CP + Y+ C C + S+ Q EGC C G + Y V ++ CGC
Sbjct: 2222 CPSHREYQACGPAEEPTCKS-SSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGP 2280
Query: 3992 NGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSC--KPGQVCQPSGGILSCVTK--DPC 4047
+ V E + D C+ G ++CQ C KP C G L+ D C
Sbjct: 2281 DNVPREFGEHFEFD-CKNCVCLEGGSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
Query: 4048 HGVTCRPQET--CKEQGGQGVCLPNYE 4072
+T T CKE+ VC +E
Sbjct: 2340 CNITVCKCNTSLCKEK--PSVCPLGFE 2364
Score = 125 bits (314), Expect = 1e-27
Identities = 113/425 (26%), Positives = 166/425 (39%), Gaps = 42/425 (9%)
Query: 4816 RCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCG-RCLANGGIHYITLDGRVYDL 4874
+ EC P TC G + R+ED C C C G HY+T DG Y
Sbjct: 1905 KVECEPPPMPTCSNGL-----QPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSY 1959
Query: 4875 HGSCSYVLAQVCHPKPGDEDFSIVLEK-----NAAGDLQRLLV-------TVAGQVVSLA 4922
G+C+YVL + P ++F + ++ N R L+ + V +
Sbjct: 1960 QGNCTYVLVE--EISPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMP 2017
Query: 4923 QGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSP---F 4978
QV V+ +AVALP + V G N V+ + G+ + ++G L S+ P F
Sbjct: 2018 MQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYNG---LSFSVRLPYHRF 2074
Query: 4979 RGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSK-GCGEGCGPQGCPVCL 5037
G CG SDD +LP+G S+ E W SK C P
Sbjct: 2075 GNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVT 2134
Query: 5038 AE---ETAPYES---NEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLC 5091
+T P++ + C +++ FA C A++ P Y+ CV+D C G + C
Sbjct: 2135 VPGGGKTTPHKDCTPSPLCQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPG-SSLEC 2191
Query: 5092 RSLAAYTAACQAAGVAVKPWR--TDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 5149
SL AY A C + + WR T C + CP+H Y C + +C + S T
Sbjct: 2192 ASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NT 2249
Query: 5150 RCFEGCECDDRFL-LSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTC 5208
EGC C + + + G + V+ CGC DC SG+ C
Sbjct: 2250 VLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFGEHFEFDCKNCVCLEGGSGIIC 2309
Query: 5209 QAAGC 5213
Q C
Sbjct: 2310 QPKRC 2314
Score = 124 bits (311), Expect = 3e-27
Identities = 122/442 (27%), Positives = 183/442 (41%), Gaps = 60/442 (13%)
Query: 2057 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCH 2103
+P+ +G QPV + C WGDPHYVT DG +++QG C Y+L
Sbjct: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
Query: 2104 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 2158
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
Query: 2159 TLPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVPAAYAGS----LCGLCGN 2213
LP++ L + SG + VV G+ ++++G SF +R+P G+ CG C N
Sbjct: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
Query: 2214 YNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVI 2269
D D + G + + Q SKP CP + ++ + GG
Sbjct: 2088 TTSD--DCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHK 2145
Query: 2270 SATDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 2320
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 2146 DCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQ 2204
Query: 2321 GAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG-- 2376
L +WR C +CP+H Y+ CG + +C S S+ + + EGC C G
Sbjct: 2205 NICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTM 2262
Query: 2377 -FVLSGDTCVPVGQCGCLHDDRY-YPLGQTFYPGPGCDSLCRCREGGE-VSCEPSSCG-- 2431
+ D CV CGC+ D G+ F C + C C EGG + C+P C
Sbjct: 2263 NYAPGFDVCVKT--CGCVGPDNVPREFGEHF--EFDCKN-CVCLEGGSGIICQPKRCSQK 2317
Query: 2432 PHETCRPSGGSLGCVAVGSTTC 2453
P C G L + TC
Sbjct: 2318 PVTHCVEDGTYLATEVNPADTC 2339
Score = 124 bits (310), Expect = 3e-27
Identities = 122/442 (27%), Positives = 182/442 (41%), Gaps = 60/442 (13%)
Query: 3258 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 3304
+P+ +G QPV + C WGDPHYVT DG + +QG C Y+L
Sbjct: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
Query: 3305 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 3359
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
Query: 3360 TLPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVPAAYAGS----LCGLCGN 3414
LP++ L + SG + VV G+ ++++G SF +R+P G+ CG C N
Sbjct: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
Query: 3415 YNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVI 3470
D D + G + + Q SKP CP + ++ + GG
Sbjct: 2088 TTSD--DCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHK 2145
Query: 3471 SATDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAA 3521
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 2146 DCTPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQ 2204
Query: 3522 GAQLREWRRPDF--CPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAG-- 3577
L +WR C +CP+H Y+ CG + +C S S+ + + EGC C G
Sbjct: 2205 NICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTM 2262
Query: 3578 -FVLSGDTCVPVGQCGCLHDDRY-YPLGQTFYPGPGCDSLCRCREGGE-VSCEPSSCG-- 3632
+ D CV CGC+ D G+ F C + C C EGG + C+P C
Sbjct: 2263 NYAPGFDVCVKT--CGCVGPDNVPREFGEHF--EFDCKN-CVCLEGGSGIICQPKRCSQK 2317
Query: 3633 PHETCRPSGGSLGCVAVGSTTC 3654
P C G L + TC
Sbjct: 2318 PVTHCVEDGTYLATEVNPADTC 2339
Score = 119 bits (297), Expect = 1e-25
Identities = 121/456 (26%), Positives = 178/456 (39%), Gaps = 59/456 (12%)
Query: 825 TCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMG 884
TC+ V D C C CY C G GDPHYV+FDG + + G
Sbjct: 1915 TCSNGLQPVRVEDPDGCCWHWECD-------CY------CTGWGDPHYVTFDGLYYSYQG 1961
Query: 885 TCTYLLVGSCGQNAALPAFRVLVENEH---RGSQTVSYTRAVRVEARGVKVAVRREYPGQ 941
CTY+LV + ++ F V ++N H + T VR E + V + P Q
Sbjct: 1962 NCTYVLVEEI--SPSVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQ 2019
Query: 942 VLVDDVLQYLPFQAADGQVQVFRQGRDAVVR-TDFGLTVTYDWNARVTAKVP-SSYAEAL 999
V V Q + ++V++ G + VV + G+ V+Y+ + ++P +
Sbjct: 2020 VQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELGVLVSYN-GLSFSVRLPYHRFGNNT 2078
Query: 1000 CGLCGNFNGDPADDLALRGGGQAANALAFGNSW--QEETRPGC----------GATEPG- 1046
G CG +DD L G +N A + W + ++P C T PG
Sbjct: 2079 KGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGG 2138
Query: 1047 --DCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGP 1104
P D + C ++ D F +CH+ + PQ CV+D C +PG S
Sbjct: 2139 GKTTPHKDCTPSPL------CQLIKD--SLFAQCHALVPPQHYYDACVFDSCFMPGSSLE 2190
Query: 1105 LCDALATYAAACQAAGATVHPWRSEE--LCPLSCPPHSHYEACSYGCPLSCGDLPVPGGC 1162
C +L YAA C + WR+ C + CP H Y+AC +C
Sbjct: 2191 -CASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN- 2247
Query: 1163 GSECHEGCVCDEG---FALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEG 1219
+ EGC C EG +A + C + +CGCV G + P + C C EG
Sbjct: 2248 NTVLVEGCFCPEGTMNYAPGFDVC--VKTCGCV--GPDNVPREFGEHFEFDCKNCVCLEG 2303
Query: 1220 GL-VSCESSSCG--PHEACQPSGGSLGCVAVGSSTC 1252
G + C+ C P C G L + TC
Sbjct: 2304 GSGIICQPKRCSQKPVTHCVEDGTYLATEVNPADTC 2339
Score = 117 bits (294), Expect = 2e-25
Identities = 119/428 (27%), Positives = 183/428 (42%), Gaps = 56/428 (13%)
Query: 4459 LPSGQHGCQPVSTAE-------------CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 4505
+P+ +G QPV + C WGDPHYVT DG + +QG C Y+L
Sbjct: 1913 MPTCSNGLQPVRVEDPDGCCWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEIS 1972
Query: 4506 GPPLGAENFTVTVANEH-RGSQAVSYTRSVTLQIYNHSLTLSA----RWPRKLQVDGVFV 4560
+NF V + N H + VS R++ ++ + + ++QV+ V
Sbjct: 1973 P---SVDNFGVYIDNYHCDPNDKVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAV 2029
Query: 4561 ALPFQLDSLLHAHLSGADVVVTTTS-GLSLAFDGDSFVRLRVP-AAYAASLCGLCGNYNQ 4618
ALP++ L + SG + VV G+ ++++G SF +R+P + + G CG
Sbjct: 2030 ALPYKKYG-LEVYQSGINYVVDIPELGVLVSYNGLSF-SVRLPYHRFGNNTKGQCGTCTN 2087
Query: 4619 DPADDLKAVGGK-PAGWQVGGAQGCGECVSKP-CPSPCTPEQQESF---GGPDACGVISA 4673
+DD G+ + + Q SKP CP + ++ + GG
Sbjct: 2088 TTSDDCILPSGEIVSNCEAAADQWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDC 2147
Query: 4674 TDGPL---------APCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGA 4724
T PL A CH LVPP Y+ C+ D+C + G C ++ Y A C
Sbjct: 2148 TPSPLCQLIKDSLFAQCHALVPPQHYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNI 2206
Query: 4725 QLGEWRRPDF--CPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAG---F 4779
L +WR C ++CP+H Y+ CG + +C S S+ + + EGC C G +
Sbjct: 2207 CL-DWRNHTHGACLVECPSHREYQACGPAEEPTCKSSSSQQN-NTVLVEGCFCPEGTMNY 2264
Query: 4780 VLSGDTCVPVGQCGCL-HDGRYYPLGEVFYPGPECERRCECGPGGH-VTCQ-EGAACGPH 4836
D CV CGC+ D GE F +C + C C GG + CQ + + P
Sbjct: 2265 APGFDVCVKT--CGCVGPDNVPREFGEHF--EFDC-KNCVCLEGGSGIICQPKRCSQKPV 2319
Query: 4837 EECRLEDG 4844
C +EDG
Sbjct: 2320 THC-VEDG 2326
Score = 107 bits (266), Expect = 4e-22
Identities = 89/352 (25%), Positives = 139/352 (39%), Gaps = 34/352 (9%)
Query: 444 CEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCS 503
C + A G Q G VC G+ HY TFDG + G C Y C
Sbjct: 12 CLALSLAGGSELQTEGRTRN---HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR 68
Query: 504 EDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEV----GFVLVDNQRSRL 559
+ F+V K + + V + + ++ LTR V + L
Sbjct: 69 --GSYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGL 126
Query: 560 PVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPA 619
+ S+ +VY GL + ++ + L L L +F++ CGLCG+YNG +
Sbjct: 127 LIEKSDAYTKVYSRA---------GLTLMWNREDALMLELDTKFRNHTCGLCGDYNGLQS 177
Query: 620 DDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLT 678
DG L +EF + K++ D +CED + PA C+ +A+ C L
Sbjct: 178 YSEFLSDGVLF-SPLEFGNMQKINQPDVVCEDPEEEVAPASCSEHRAE-------CERLL 229
Query: 679 KLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSP 738
+ FA C D + P+L C D C G +C ++ +++ C G G+WR+
Sbjct: 230 TAEA-FADCQDLVPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTA 288
Query: 739 AN-----CPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPG 785
+ +CP N Y G C +C+ S C ++GC C G
Sbjct: 289 TSAVSPGASKTCPGNLVYLESGSPCMDTCSHLEVSSLCEEHR-MDGCFCPEG 339
Score = 104 bits (259), Expect = 3e-21
Identities = 84/319 (26%), Positives = 129/319 (40%), Gaps = 30/319 (9%)
Query: 4474 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 4533
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 4534 VTLQIYNHSLTLSARWPRKLQV-DGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 4592
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 4593 GDSFVRLRVPAAYAASLCGLCGNYNQ-DPADDLKAVGGKPAGWQVGGAQG-------CGE 4644
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 4645 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 4704
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 4705 PGGLCPAVATYVAACQAAGAQLGEWRRPDF-----CPLQCPAHSHYELCGDSCPVSCPSL 4759
+C VA + C AG + G WR CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
Query: 4760 SAPEGCESACREGCVCDAG 4778
CE +GC C G
Sbjct: 321 EVSSLCEEHRMDGCFCPEG 339
Score = 103 bits (256), Expect = 6e-21
Identities = 83/319 (26%), Positives = 128/319 (40%), Gaps = 30/319 (9%)
Query: 2072 CQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 2131
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 2132 VTLQIYNHSLTLSARWPRKLQV-DGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 2190
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 2191 GDSFVRLRVPAAYAGSLCGLCGNYN-QDPADDLKAVGGKPAGWQVGGAQG-------CGE 2242
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 2243 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 2302
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 2303 PGGLCPAVATYVAACQAAGAQLREWRRPDF-----CPFQCPAHSHYELCGDSCPGSCPSL 2357
+C VA + C AG + WR CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
Query: 2358 SAPEGCESACREGCVCDAG 2376
CE +GC C G
Sbjct: 321 EVSSLCEEHRMDGCFCPEG 339
Score = 102 bits (255), Expect = 8e-21
Identities = 109/392 (27%), Positives = 157/392 (40%), Gaps = 39/392 (9%)
Query: 4136 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVA---DFGLQ 4192
VV +A N+ + K + G V +N + LP A SV + +S ++V+ LQ
Sbjct: 348 VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVRLQ 404
Query: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 4252
V ++ VTL + G V GLCGN + +D +G + + + +W+A
Sbjct: 405 VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS-- 462
Query: 4253 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVC 4312
C D+ C + +C L T PF CH+ V P ++K C D C
Sbjct: 463 -SCHDKLDWLDDPCSLNIESANYAEHWCSLLKK-TETPFGRCHSAVDPAEYYKRCKYDTC 520
Query: 4313 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGPPCPASC 4369
+ D LC AL+SY AC A GV++ WR V C +CP + + C +C
Sbjct: 521 NCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTC 579
Query: 4370 PSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADG 4428
S + + + V+GC C D F+ RCVPL C C+ G Y EAG D
Sbjct: 580 RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG-----DV 633
Query: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS--------TAECQAWGDP 4480
Q RC G L C +G+ C P C ++ CQ
Sbjct: 634 VVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSNLTALATSKPRALSCQTLAAG 691
Query: 4481 HY--------VTLDGHRFDFQGTCEYLLSAPC 4504
+Y V DG D +G C PC
Sbjct: 692 YYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 723
Score = 102 bits (254), Expect = 1e-20
Identities = 83/319 (26%), Positives = 128/319 (40%), Gaps = 30/319 (9%)
Query: 3273 CQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRS 3332
C WG+ HY T DG F F G C+Y ++ C G + F V + ++A + S
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRG---SYKEFAVHLKRGPGQAEAPAGVES 93
Query: 3333 VTLQIYNHSLTLSARWPRKLQV-DGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFD 3391
+ L I + ++ L+ R L V +G V+ P LL S A V + +GL+L ++
Sbjct: 94 ILLTIKDDTIYLT----RHLAVLNGAVVSTPHYSPGLL-IEKSDAYTKVYSRAGLTLMWN 148
Query: 3392 GDSFVRLRVPAAYAGSLCGLCGNYN-QDPADDLKAVGGKPAGWQVGGAQG-------CGE 3443
+ + L + + CGLCG+YN + + G + + G Q C +
Sbjct: 149 REDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLEFGNMQKINQPDVVCED 208
Query: 3444 CVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGH 3503
+ P+ C+ + E C + + A C LVP Y + C D C+ G
Sbjct: 209 PEEEVAPASCSEHRAE-------CERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGG 260
Query: 3504 PGGLCPAVATYVAACQAAGAQLREWRRPDF-----CPFQCPAHSHYELCGDSCPGSCPSL 3558
+C VA + C AG + WR CP + Y G C +C L
Sbjct: 261 DTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHL 320
Query: 3559 SAPEGCESACREGCVCDAG 3577
CE +GC C G
Sbjct: 321 EVSSLCEEHRMDGCFCPEG 339
Score = 102 bits (254), Expect = 1e-20
Identities = 109/392 (27%), Positives = 157/392 (40%), Gaps = 39/392 (9%)
Query: 2935 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA---DFGLQ 2991
VV +A N+ + K + G V +N + LP A SV + +S ++V+ LQ
Sbjct: 348 VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVRLQ 404
Query: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051
V ++ VTL + G V GLCGN + +D +G + + + +W+A
Sbjct: 405 VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS-- 462
Query: 3052 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 3111
C D+ C + +C L T PF CH+ V P ++K C D C
Sbjct: 463 -SCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRCHSAVDPAEYYKRCKYDTC 520
Query: 3112 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGPPCPASC 3168
+ D LC AL+SY AC A GV++ WR V C +CP + + C +C
Sbjct: 521 NCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTC 579
Query: 3169 PSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADG 3227
S + + + V+GC C D F+ RCVPL C C+ G Y EAG D
Sbjct: 580 RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG-----DV 633
Query: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVS--------TAECQAWGDP 3279
Q RC G L C +G+ C P C ++ CQ
Sbjct: 634 VVRQEERCVCRDGRLHCRQIRL-IGQSC-TAPKIHMDCSNLTALATSKPRALSCQTLAAG 691
Query: 3280 HY--------VTLDGHRFDFQGTCEYLLSAPC 3303
+Y V DG D +G C PC
Sbjct: 692 YYHTECVSGCVCPDGLMDDGRGGCVVEKECPC 723
Score = 102 bits (254), Expect = 1e-20
Identities = 75/235 (31%), Positives = 97/235 (41%), Gaps = 27/235 (11%)
Query: 1001 GLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQ 1060
GLCGNFNG DD G A F N+W+ ++ C LD + ++
Sbjct: 427 GLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS--SCH----DKLDWLDDPCSLNIE 480
Query: 1061 SKNE----CGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAAC 1116
S N C +L + PF CHS +DP + C YD C LC AL++YA AC
Sbjct: 481 SANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARAC 540
Query: 1117 QAAGATVHPWRSEELCPL---SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHE----- 1168
A G + WR E +C SCP + C +C L S C E
Sbjct: 541 TAKGVMLWGWR-EHVCNKDVGSCPNSQVFLYNLTTCQQTCRSL---SEADSHCLEGFAPV 596
Query: 1169 -GCVC-DEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGL 1221
GC C D F C+PLA C C H+G Y G + C C++G L
Sbjct: 597 DGCGCPDHTFLDEKGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDGRL 648
Score = 102 bits (253), Expect = 1e-20
Identities = 94/317 (29%), Positives = 137/317 (43%), Gaps = 21/317 (6%)
Query: 1734 VVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVA---DFGLQ 1790
VV +A N+ + K + G V +N + LP A SV + +S ++V+ LQ
Sbjct: 348 VVLLADKKKNVVVFKSD-GSVLLNELQVNLPHVTAS--FSVFRPSSYHIMVSMAIGVRLQ 404
Query: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
V ++ VTL + G V GLCGN + +D +G + + + +W+A
Sbjct: 405 VQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQS-- 462
Query: 1851 PLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVC 1910
C D+ C + +C L T PF CH+ V P ++K C D C
Sbjct: 463 -SCHDKLDWLDDPCSLNIESANYAEHWCS-LLKKTETPFGRCHSAVDPAEYYKRCKYDTC 520
Query: 1911 MGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI---TCPENSHYEVCGSPCPASC 1967
+ D LC AL+SY AC A GV++ WR V C +CP + + + C +C
Sbjct: 521 NCQNNEDCLCAALSSYARACTAKGVMLWGWREHV-CNKDVGSCPNSQVFLYNLTTCQQTC 579
Query: 1968 PSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADG 2026
S + + + V+GC C D F+ RCVPL C C+ G Y EAG D
Sbjct: 580 RSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAK-CSCYHRGLYLEAG-----DV 633
Query: 2027 TCSQWCRCGPGGGSLVC 2043
Q RC G L C
Sbjct: 634 VVRQEERCVCRDGRLHC 650
Score = 98.2 bits (243), Expect = 2e-19
Identities = 80/317 (25%), Positives = 134/317 (42%), Gaps = 28/317 (8%)
Query: 4856 CLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKN-----AAGDLQRL 4910
C G HY T DG V+ G C Y A C + ++F++ L++ A ++ +
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 4911 LVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHL 4970
L+T+ + L + V ++G V+ P + + + + GL L+++ + L
Sbjct: 95 LLTIKDDTIYLTRHLAV-LNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDAL 153
Query: 4971 LMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGP 5030
++ + + FR CGLCG++NG S L +G S +E FG + C + P
Sbjct: 154 MLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPDVVCED---P 209
Query: 5031 QGCPVCLAEETAPYESNE---ACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDK 5087
+ EE AP +E C +L + FA CQ ++ Y R C D C G
Sbjct: 210 E-------EEVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCRCPGGD 261
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSF-----CPLHCPAHSHYSICTRTCQGSCAALS 5142
+C ++A ++ C AG WRT + CP + Y C +C+ L
Sbjct: 262 TCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTCSHLE 321
Query: 5143 GLTGCTTRCFEGCECDD 5159
+ C +GC C +
Sbjct: 322 VSSLCEEHRMDGCFCPE 338
Score = 98.2 bits (243), Expect = 2e-19
Identities = 80/280 (28%), Positives = 111/280 (39%), Gaps = 24/280 (8%)
Query: 2158 VTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA--GSLCGLCGNYN 2215
V LP S S ++V+ G+ L ++L V A G + GLCGN+N
Sbjct: 374 VNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFN 433
Query: 2216 QDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGPDACGVIS 2270
DD K G G A + C K PC+ + + C ++
Sbjct: 434 GLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLK 493
Query: 2271 ATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP 2330
T+ P CH V PA+Y++ C D C Q + LC A+++Y AC A G L WR
Sbjct: 494 KTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWRE- 552
Query: 2331 DFC---PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE------GCVC-DAGFVLS 2380
C CP + +C +C SLS +S C E GC C D F+
Sbjct: 553 HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCPDHTFLDE 609
Query: 2381 GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 2420
CVP+ +C C H Y G + C CR+G
Sbjct: 610 KGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDG 646
Score = 98.2 bits (243), Expect = 2e-19
Identities = 80/280 (28%), Positives = 111/280 (39%), Gaps = 24/280 (8%)
Query: 3359 VTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYA--GSLCGLCGNYN 3416
V LP S S ++V+ G+ L ++L V A G + GLCGN+N
Sbjct: 374 VNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFN 433
Query: 3417 QDPADDLKAVGGKPAGWQVGGA---QGCGECVSKP--CPSPCTPEQQESFGGPDACGVIS 3471
DD K G G A + C K PC+ + + C ++
Sbjct: 434 GLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLK 493
Query: 3472 ATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP 3531
T+ P CH V PA+Y++ C D C Q + LC A+++Y AC A G L WR
Sbjct: 494 KTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNEDCLCAALSSYARACTAKGVMLWGWRE- 552
Query: 3532 DFC---PFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE------GCVC-DAGFVLS 3581
C CP + +C +C SLS +S C E GC C D F+
Sbjct: 553 HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSE---ADSHCLEGFAPVDGCGCPDHTFLDE 609
Query: 3582 GDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREG 3621
CVP+ +C C H Y G + C CR+G
Sbjct: 610 KGRCVPLAKCSCYHRGLYLEAGDVVVRQ---EERCVCRDG 646
Score = 88.6 bits (218), Expect = 2e-16
Identities = 85/328 (25%), Positives = 128/328 (39%), Gaps = 33/328 (10%)
Query: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732
C WG+ HY +FDG F F G C+Y A + C G F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
Query: 1733 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVTQGASKALLVADFGLQ 1790
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 1791 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 1850
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 1851 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 1909
+C D P +C E R E C L T F C VP E + + C D
Sbjct: 204 VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
Query: 1910 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGSPCP 1964
C G +C +A + C AG +WR G TCP N Y GSPC
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
Query: 1965 ASCPSPAPLTTPAVCEGPCVEGCQCDAG 1992
+C + L ++CE ++GC C G
Sbjct: 315 DTC---SHLEVSSLCEEHRMDGCFCPEG 339
Score = 86.7 bits (213), Expect = 6e-16
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 33/328 (10%)
Query: 2874 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 2933
C WG+ HY +FDG F F G C+Y A + C G F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
Query: 2934 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVTQGASKALLVADFGLQ 2991
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 2992 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 3051
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 3052 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110
+C D P +C E R E C L T F C VP E + + C D
Sbjct: 204 VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
Query: 3111 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGPPCP 3165
C G +C +A + C AG +WR G TCP N Y G PC
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
Query: 3166 ASCPSPAPLTTPAVCEGPCVEGCQCDAG 3193
+C + L ++CE ++GC C G
Sbjct: 315 DTC---SHLEVSSLCEEHRMDGCFCPEG 339
Score = 86.3 bits (212), Expect = 8e-16
Identities = 84/328 (25%), Positives = 127/328 (38%), Gaps = 33/328 (10%)
Query: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134
C WG+ HY +FDG F F G C+Y A + C G F V K A + V
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFA-SDCRG----SYKEFAVHLKRGPGQAEAPAGV 91
Query: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVA--DGRISVAQGASKALLVADFGLQ 4192
+ ++I D I R VL VS + + + + + + GL
Sbjct: 92 ESIL-------LTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRAGLT 144
Query: 4193 VSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWD 4252
+ ++ + + L + + CGLCG+ + + + +G L + +G + D
Sbjct: 145 LMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVLFSPLE-FGNMQKINQPD 203
Query: 4253 PLCWDECRGSCP-TCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311
+C D P +C E R E C L T F C VP E + + C D
Sbjct: 204 VVCEDPEEEVAPASCSEHRAE-------CERLL--TAEAFADCQDLVPLEPYLRACQQDR 254
Query: 4312 CMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-----GCEITCPENSHYEVCGPPCP 4366
C G +C +A + C AG +WR G TCP N Y G PC
Sbjct: 255 CRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCM 314
Query: 4367 ASCPSPAPLTTPAVCEGPCVEGCQCDAG 4394
+C + L ++CE ++GC C G
Sbjct: 315 DTC---SHLEVSSLCEEHRMDGCFCPEG 339
Score = 83.6 bits (205), Expect = 5e-15
Identities = 88/337 (26%), Positives = 127/337 (37%), Gaps = 43/337 (12%)
Query: 1248 GSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 1307
G + C G+ HY TFDG F F G C Y A C R FAV ++ G G+
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
Query: 1308 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 1364
I + + + T+ L + +NG + P I S + V GL
Sbjct: 88 PAGVESILLTIKDDTIYLTRH--LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
Query: 1365 RVAYDLVYYVRVTVPGNYYQQMCGLCGNYNG-DPKDDFQKPNGSQAGNANEFGNSWEEVV 1423
+ ++ + + + + CGLCG+YNG +F + + EFGN +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ 201
Query: 1424 PDSPCLPPTPCPPGSEDCIPS----HKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVD 1479
PD C P E+ P+ H+ E E+ E F + C LV
Sbjct: 202 PDVVCEDP------EEEVAPASCSEHRA--ECERLLTAEAF-----------ADCQDLVP 242
Query: 1480 PQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETF-----CPMECPP 1534
+ L+ C D C G + +CS + + C AGG WRT T CP
Sbjct: 243 LEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPG 302
Query: 1535 NSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSG 1571
N Y C CS L C++ +GC C G
Sbjct: 303 NLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
Score = 79.7 bits (195), Expect = 7e-14
Identities = 86/333 (25%), Positives = 124/333 (37%), Gaps = 35/333 (10%)
Query: 2449 GSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 2508
G C G+ HY TFDG F F G C Y A C R FAV ++ G G+
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
Query: 2509 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 2565
I + + + T+ L + +NG + P I S + V GL
Sbjct: 88 PAGVESILLTIKDDTIYLTRH--LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
Query: 2566 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG-DPKDDFQKPNGSQAGNANEFGNSWEEVV 2624
+ ++ + + + + CGLCG+YNG +F + + EFGN +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ 201
Query: 2625 PDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGP 2684
PD C P EE P +++ E C L + + C LV +
Sbjct: 202 PDVVCED------------PEEEVAPASCSEHRAE--CERLLTAEA-FADCQDLVPLEPY 246
Query: 2685 LKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETF-----CPMECPQNSHY 2739
L+ C D C G + +CS + + C AGG+ WR T CP N Y
Sbjct: 247 LRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVY 306
Query: 2740 ELCADTCSLGCSALSAPLQCPDGCAEGCQCDSG 2772
C CS L C + +GC C G
Sbjct: 307 LESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
Score = 79.3 bits (194), Expect = 9e-14
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 31/323 (9%)
Query: 864 CQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAV 923
C G+ HY +FDG F F G C Y C + F V ++ ++ + ++
Sbjct: 37 CSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAVHLKRGPGQAEAPAGVESI 94
Query: 924 RVEARGVKVAVRREYPGQVLVDDVLQ---YLP---FQAADGQVQVFRQGRDAVVRTDFGL 977
+ + + + R VL V+ Y P + +D +V+ + GL
Sbjct: 95 LLTIKDDTIYLTRHLA--VLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA---------GL 143
Query: 978 TVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETR 1037
T+ ++ + ++ + + CGLCG++NG + L G + L FGN Q+ +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL-SDGVLFSPLEFGNM-QKINQ 201
Query: 1038 PGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL 1097
P +P + + A + + EC L + F +C + + +R C DRC
Sbjct: 202 PDVVCEDPEE----EVAPASCSEHRAECERLLTAEA-FADCQDLVPLEPYLRACQQDRCR 256
Query: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEEL-----CPLSCPPHSHYEACSYGCPLS 1152
PG +C +A ++ C AG WR+ +CP + Y C +
Sbjct: 257 CPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDT 316
Query: 1153 CGDLPVPGGCGSECHEGCVCDEG 1175
C L V C +GC C EG
Sbjct: 317 CSHLEVSSLCEEHRMDGCFCPEG 339
Score = 78.6 bits (192), Expect = 2e-13
Identities = 86/339 (25%), Positives = 122/339 (35%), Gaps = 47/339 (13%)
Query: 3650 GSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSV 3709
G C G+ HY TFDG F F G C Y A C R FAV ++ G G+
Sbjct: 33 GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDC--RGSYKEFAV---HLKRGPGQAEA 87
Query: 3710 ---TRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGL 3766
I + + + T+ L + +NG + P I S + V GL
Sbjct: 88 PAGVESILLTIKDDTIYLTRH--LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA--GL 143
Query: 3767 RVAYDLVYYVRVTVPGNYYQLMCGLCGNYNG-DPKDDFQKPNGSQAGNANEFGNSWEEVV 3825
+ ++ + + + + CGLCG+YNG +F + + EFGN +
Sbjct: 144 TLMWNREDALMLELDTKFRNHTCGLCGDYNGLQSYSEFL--SDGVLFSPLEFGNMQKINQ 201
Query: 3826 PDSPC------LPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKL 3879
PD C + P +C A C E+ E F + C L
Sbjct: 202 PDVVCEDPEEEVAPASCSEHRAEC----------ERLLTAEAF-----------ADCQDL 240
Query: 3880 VDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETF-----CPMEC 3934
V + L+ C D C G + +CS + + C AGG WR T C
Sbjct: 241 VPLEPYLRACQQDRCRCPGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTC 300
Query: 3935 PQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSG 3973
P N Y C CS L C + +GC C G
Sbjct: 301 PGNLVYLESGSPCMDTCSHLEVSSLCEEHRMDGCFCPEG 339
Score = 36.6 bits (83), Expect = 0.69
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 11/92 (11%)
Query: 5294 VHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGAN 5353
V +F DG V L N L+V+LP AS SV R ++V GV++ +
Sbjct: 358 VVVFKSDGSVLL--------NELQVNLP-HVTASFSVFRPSSYHIMVSMAIGVRLQVQLA 408
Query: 5354 GKVAVIVSNDHA--GKLCGACGNFDGDQTNDW 5383
+ + V+ D A G++ G CGNF+G + +D+
Sbjct: 409 PVMQLFVTLDQASQGQVQGLCGNFNGLEGDDF 440
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 211 bits (538), Expect = 1e-53
Identities = 167/497 (33%), Positives = 211/497 (42%), Gaps = 72/497 (14%)
Query: 3943 CADTCSLGCS-----ALSAPLQCPDGCAEGCQC-DSGFLYNGQAC-----------VPIQ 3985
C TC+ S L + L PD C CQC D +L QAC P
Sbjct: 1015 CCPTCAEALSNCSEGLLGSELAPPDPCYT-CQCQDLTWLCIHQACPELSCPLSERHTPPG 1073
Query: 3986 QC---------GCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSG 4036
C C H G + +D C C+C G V CQ C P
Sbjct: 1074 SCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAG-TVRCQSQRCSP-------- 1123
Query: 4037 GILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGT 4096
LSC P P C CLP A+C +GDPHY +FDGR FQG+
Sbjct: 1124 --LSC---GPDKAPALSPGSCCPR------CLPR-PASCMAFGDPHYRTFDGRLLHFQGS 1171
Query: 4097 CNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKV 4156
C+YVLA G F+V N +RG V++ + V V + + +D G V
Sbjct: 1172 CSYVLAKDCHSG-------DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD--GAV 1222
Query: 4157 RVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 4216
V+G ALP + + + V +L A GLQV +D +V+V++P SY G CGL
Sbjct: 1223 TVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
Query: 4217 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG--WDPLCWDECRGSCPTCPEDRLEQY 4274
CGN + +D P G L PS +G SW+ W R P +
Sbjct: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
Query: 4275 EGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCM---GGGDRDILCKALASYVAA 4331
E CG L S PF+ CHA VPPE FF CV D+C G LC AL +Y +
Sbjct: 1342 EANARCGVLKS---SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASH 1398
Query: 4332 CQAAGVVIEDWRAQVGCEITCP--ENSHYEVCGPPCPASC-PSPAPL-TTPAVCEGPCVE 4387
C+ AGV WR C + CP ++ CGPPCP +C PL A C PCV
Sbjct: 1399 CRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP 1457
Query: 4388 GCQCDAGFVLSADRCVP 4404
GCQC AG V C+P
Sbjct: 1458 GCQCPAGLVEHEAHCIP 1474
Score = 210 bits (535), Expect = 3e-53
Identities = 166/497 (33%), Positives = 210/497 (42%), Gaps = 72/497 (14%)
Query: 2742 CADTCSLGCS-----ALSAPLQCPDGCAEGCQC-DSGFLYNGQAC-----------VPIQ 2784
C TC+ S L + L PD C CQC D +L QAC P
Sbjct: 1015 CCPTCAEALSNCSEGLLGSELAPPDPCYT-CQCQDLTWLCIHQACPELSCPLSERHTPPG 1073
Query: 2785 QC---------GCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSG 2835
C C H G + +D C C+C G V CQ C P
Sbjct: 1074 SCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAG-TVRCQSQRCSP-------- 1123
Query: 2836 GILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGT 2895
LSC P P C CLP A+C +GDPHY +FDGR FQG+
Sbjct: 1124 --LSC---GPDKAPALSPGSCCPR------CLPR-PASCMAFGDPHYRTFDGRLLHFQGS 1171
Query: 2896 CNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKV 2955
C+YVLA G F+V N +RG V++ + V V + + +D G V
Sbjct: 1172 CSYVLAKDCHSG-------DFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQD--GAV 1222
Query: 2956 RVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGL 3015
V+G ALP + + + V +L A GLQV +D +V+V++P SY G CGL
Sbjct: 1223 TVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
Query: 3016 CGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG--WDPLCWDECRGSCPTCPEDRLEQY 3073
CGN + +D P G L PS +G SW+ W R P +
Sbjct: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
Query: 3074 EGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM---GGGDRDILCKALASYVAA 3130
E CG L PF+ CHA VPPE FF CV D+C G LC AL +Y +
Sbjct: 1342 EANARCGVL---KSSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASH 1398
Query: 3131 CQAAGVVIEDWRAQVGCEITCP--ENSHYEVCGPPCPASC-PSPAPL-TTPAVCEGPCVE 3186
C+ AGV WR C + CP ++ CGPPCP +C PL A C PCV
Sbjct: 1399 CRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP 1457
Query: 3187 GCQCDAGFVLSADRCVP 3203
GCQC AG V C+P
Sbjct: 1458 GCQCPAGLVEHEAHCIP 1474
Score = 207 bits (527), Expect = 2e-52
Identities = 170/517 (32%), Positives = 216/517 (41%), Gaps = 80/517 (15%)
Query: 1528 CP--MECPPNSHY----ELCADTCSLGCSALS--------APP------QCQD------- 1560
CP + CPP+ + C TC+ S S APP QCQD
Sbjct: 996 CPSLVGCPPSQLLPPGPQHCCPTCAEALSNCSEGLLGSELAPPDPCYTCQCQDLTWLCIH 1055
Query: 1561 -GCAE-GCQCDSGFLYNGQAC----VPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAG 1614
C E C G C P Q C H G + +D C C+C AG
Sbjct: 1056 QACPELSCPLSERHTPPGSCCPVCRAPTQSC--VHQGREVASGERWTVDTCTS-CSCMAG 1112
Query: 1615 KGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCW 1674
+ CQ C P LSC P P C CLP A+C
Sbjct: 1113 T-VRCQSQRCSP----------LSC---GPDKAPALSPGSCCPR------CLPR-PASCM 1151
Query: 1675 LWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRV 1734
+GDPHY +FDGR FQG+C+YVLA G F+V N +RG V++ +
Sbjct: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSG-------DFSVHVTNDDRGRSGVAWTQE 1204
Query: 1735 VTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYD 1794
V V + + +D G V V+G ALP + + + V +L A GLQV +D
Sbjct: 1205 VAVLLGDMAVRLLQD--GAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWD 1261
Query: 1795 WNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPG--WDPL 1852
+V+V++P SY G CGLCGN + +D P G L PS +G SW+ W
Sbjct: 1262 GQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGR 1321
Query: 1853 CWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCM- 1911
R P + E CG L PF+ CHA VPPE FF CV D+C
Sbjct: 1322 PCSAGREVDPCRAAGYRARREANARCGVL---KSSPFSRCHAVVPPEPFFAACVYDLCAC 1378
Query: 1912 --GGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCP--ENSHYEVCGSPCPASC 1967
G LC AL +Y + C+ AGV WR C + CP ++ CG PCP +C
Sbjct: 1379 GPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTC 1437
Query: 1968 -PSPAPL-TTPAVCEGPCVEGCQCDAGFVLSADRCVP 2002
PL A C PCV GCQC AG V C+P
Sbjct: 1438 FNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIP 1474
Score = 207 bits (526), Expect = 3e-52
Identities = 183/560 (32%), Positives = 237/560 (42%), Gaps = 85/560 (15%)
Query: 4657 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 4711
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
Query: 4712 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELC-GDSCP-VSCPSL---SAPEGCE 4766
A ++ C + G E PD C C LC +CP +SCP + P C
Sbjct: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
Query: 4767 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818
CR + CV V SG DTC C C+ G V C+ +
Sbjct: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCM-------AGTV-----RCQSQ-R 1120
Query: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCL-------ANGGIHYITLDGRV 4871
C P +CGP + L G +C C RCL A G HY T DGR+
Sbjct: 1121 CSP---------LSCGPDKAPALSPG--SC----CPRCLPRPASCMAFGDPHYRTFDGRL 1165
Query: 4872 YDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGD-----LQRLLVTVAGQVVSLAQGQQ 4926
GSCSYVLA+ CH DFS+ + + G Q + V + V L Q
Sbjct: 1166 LHFQGSCSYVLAKDCH----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGA 1221
Query: 4927 VTVDGEAVALP-VAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGL 4985
VTVDG VALP + + V G ++L GL++L+DG + + +S+P ++GR CGL
Sbjct: 1222 VTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGL 1281
Query: 4986 CGNFNGNWSDDFVLPNGSAASSVETFGAAWR-APGSSKGCGEGCGPQGCPVCLAEETAPY 5044
CGNFNG DD P G S FG +W+ + G G G + P A A
Sbjct: 1282 CGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR 1341
Query: 5045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA---QKGDKAFLCRSLAAYTAAC 5101
E+N CG L++ PF+ C AV+ P +F CVYDLCA A LC +L AY + C
Sbjct: 1342 EANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHC 1399
Query: 5102 QAAGVAVKPWRTDSFCPLHCPAHSHYSI------CTRTCQGSCAALSGLTG-CTTRCFEG 5154
+ AGV WR + C + CP + C RTC L L C C G
Sbjct: 1400 RQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPG 1458
Query: 5155 CECDDRFLLSQGVCIPVQDC 5174
C+C + + CIP + C
Sbjct: 1459 CQCPAGLVEHEAHCIPPEAC 1478
Score = 200 bits (508), Expect = 4e-50
Identities = 179/566 (31%), Positives = 233/566 (41%), Gaps = 83/566 (14%)
Query: 2255 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 2309
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
Query: 2310 VATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC-GDSCPG-SCPSL---SAPEGCE 2364
A ++ C + G E PD C + C LC +CP SCP + P C
Sbjct: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
Query: 2365 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 2416
CR + CV V SG DTC C C+ R
Sbjct: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCMA------------------GTVR 1115
Query: 2417 CREGGEVSCEPSSCGPHETCRPSGGSL--GCVAVGSTTCQASGDPHYTTFDGRRFDFMGT 2474
C+ C P SCGP + S GS C+ +C A GDPHY TFDGR F G+
Sbjct: 1116 CQSQ---RCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPHYRTFDGRLLHFQGS 1171
Query: 2475 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNG 2534
C YVLA+ C + F+V N G V+ T+ + V + + +RL Q VTV+G
Sbjct: 1172 CSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ-DGAVTVDG 1226
Query: 2535 VDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNY 2594
+ LP L + G V++ GL+V +D V V+VPG+Y CGLCGN+
Sbjct: 1227 HPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNF 1285
Query: 2595 NGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLPPPTCPPGSEGCIPSEECPPE 2651
NG +DD Q P G + FGNSW E + P PC P
Sbjct: 1286 NGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAA---------G 1336
Query: 2652 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLS---ILCSNIHA 2708
+ + CG+L S P S CH +V P+ C++DLC G S LC + A
Sbjct: 1337 YRARREANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEA 1394
Query: 2709 YVSACQAAGGQVEP-WRNETFCPMECP--QNSHYELCADTCSLGCSALSAPL-----QCP 2760
Y S C+ AG V P WR T C + CP + ++ C C C PL C
Sbjct: 1395 YASHCRQAG--VTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCV 1452
Query: 2761 DGCAEGCQCDSGFLYNGQACVPIQQC 2786
C GCQC +G + + C+P + C
Sbjct: 1453 RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 200 bits (508), Expect = 4e-50
Identities = 180/566 (31%), Positives = 234/566 (41%), Gaps = 83/566 (14%)
Query: 3456 EQQESFG-GPDACGVISATDGPLAP----CHGLVPPAQYFQGCLLDACQVQGHPGGLCPA 3510
E ESF G D C V P P CH P+ GC G P CP
Sbjct: 962 EPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPS--LVGCPPSQLLPPG-PQHCCPT 1018
Query: 3511 VATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELC-GDSCPG-SCPSL---SAPEGCE 3565
A ++ C + G E PD C + C LC +CP SCP + P C
Sbjct: 1019 CAEALSNC-SEGLLGSELAPPDPC-YTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCC 1076
Query: 3566 SACR---EGCVCDAGFVLSG-----DTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCR 3617
CR + CV V SG DTC C C+ R
Sbjct: 1077 PVCRAPTQSCVHQGREVASGERWTVDTCT---SCSCMA------------------GTVR 1115
Query: 3618 CREGGEVSCEPSSCGPHETCRPSGGSL--GCVAVGSTTCQASGDPHYTTFDGHRFDFMGT 3675
C+ C P SCGP + S GS C+ +C A GDPHY TFDG F G+
Sbjct: 1116 CQSQ---RCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPHYRTFDGRLLHFQGS 1171
Query: 3676 CVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNG 3735
C YVLA+ C + F+V N G V+ T+ + V + + +RL Q VTV+G
Sbjct: 1172 CSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ-DGAVTVDG 1226
Query: 3736 VDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNY 3795
+ LP L + G V++ GL+V +D V V+VPG+Y CGLCGN+
Sbjct: 1227 HPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNF 1285
Query: 3796 NGDPKDDFQKPNGSQAGNANEFGNSW---EEVVPDSPCLPPPTCPPGSAGCIPSDKCPPE 3852
NG +DD Q P G + FGNSW E + P PC SAG
Sbjct: 1286 NGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPC---------SAGREVDPCRAAG 1336
Query: 3853 LEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLS---ILCSNIHA 3909
+ + CG+L S P S CH +V P+ C++DLC G S LC + A
Sbjct: 1337 YRARREANARCGVLKS--SPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEA 1394
Query: 3910 YVSACQAAGGHVEP-WRNETFCPMECP--QNSHYELCADTCSLGCSALSAPL-----QCP 3961
Y S C+ AG V P WR T C + CP + ++ C C C PL C
Sbjct: 1395 YASHCRQAG--VTPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCV 1452
Query: 3962 DGCAEGCQCDSGFLYNGQACVPIQQC 3987
C GCQC +G + + C+P + C
Sbjct: 1453 RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 199 bits (507), Expect = 5e-50
Identities = 132/388 (34%), Positives = 177/388 (45%), Gaps = 43/388 (11%)
Query: 443 SCEGMQCAAG------QRCQVVG---GKAGCVAEST---------AVCRAQGDPHYTTFD 484
+C C AG QRC + KA ++ + A C A GDPHY TFD
Sbjct: 1103 TCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPASCMAFGDPHYRTFD 1162
Query: 485 GRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTR 544
GR G+CSY + + C D FSV N+ RG V++ V V +V L +
Sbjct: 1163 GRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAVLLGDMAVRLLQ 1218
Query: 545 GEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQ 604
G V VD LP L E L V G ++ GL V +D Q+ +S+P +Q
Sbjct: 1219 D--GAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQ 1275
Query: 605 DQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDY---LCEDGCQNNCPACT 661
+ CGLCGN+NG DD P+G L P F +SW++ +G + C G + + P
Sbjct: 1276 GRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSEGLWPGRPCSAGREVD-PCRA 1334
Query: 662 PGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVG---GERLSLCRGL 718
G E + CG+L PF+ CH + P PF CVYDLC G LC L
Sbjct: 1335 AGYRARREANARCGVLK--SSPFSRCHAVVPPEPFFAACVYDLCACGPGSSADACLCDAL 1392
Query: 719 SAYAQACLELGISVGDWRSPANCPLSCPANSR--YELCGPACPTSCNGAAAP-----SNC 771
AYA C + G++ WR P C + CP ++ CGP CP +C P ++C
Sbjct: 1393 EAYASHCRQAGVT-PTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHC 1451
Query: 772 SGRPCVEGCVCLPGFVASGGACVPASSC 799
RPCV GC C G V C+P +C
Sbjct: 1452 V-RPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 196 bits (499), Expect = 4e-49
Identities = 169/577 (29%), Positives = 236/577 (40%), Gaps = 86/577 (14%)
Query: 1856 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLAPGTGGPFTTCHAHVPPESFFKG 1904
+C C C + + G F C P G P CH P G
Sbjct: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
Query: 1905 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCP 1964
C + G + C A ++ C + G++ + C ++ + CP
Sbjct: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
Query: 1965 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 2023
SCP T P G C C+ + R V A E W
Sbjct: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
Query: 2024 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 2079
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
Query: 2080 YVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 2139
Y T DG +FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Query: 2140 SLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 2199
++ L + VDG V LPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
Query: 2200 PAAYAGSLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 2250
P +Y G CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
Query: 2251 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 2305
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
Query: 2306 -----LCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSH--YELCGDSCPGSCPSLS 2358
LC A+ Y + C+ AG WR P C CP ++ CG CP +C +
Sbjct: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
Query: 2359 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 2390
P G C C GC C AG V C+P C
Sbjct: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 195 bits (496), Expect = 9e-49
Identities = 169/577 (29%), Positives = 235/577 (40%), Gaps = 86/577 (14%)
Query: 3057 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLAPGTGGPFTTCHAHVPPESFFKG 3105
+C C C + + G F C P G P CH P G
Sbjct: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
Query: 3106 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 3165
C + G + C A ++ C + G++ + C ++ + CP
Sbjct: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
Query: 3166 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 3224
SCP T P G C C+ + R V A E W
Sbjct: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
Query: 3225 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 3280
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
Query: 3281 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 3340
Y T DG FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Query: 3341 SLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 3400
++ L + VDG V LPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
Query: 3401 PAAYAGSLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 3451
P +Y G CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
Query: 3452 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 3506
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
Query: 3507 -----LCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSH--YELCGDSCPGSCPSLS 3559
LC A+ Y + C+ AG WR P C CP ++ CG CP +C +
Sbjct: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
Query: 3560 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 3591
P G C C GC C AG V C+P C
Sbjct: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 195 bits (496), Expect = 9e-49
Identities = 169/577 (29%), Positives = 236/577 (40%), Gaps = 86/577 (14%)
Query: 4258 ECRGSCPTCPEDRLEQYEGPGF-----------CGPLSSGTGGPFTTCHAHVPPESFFKG 4306
+C C C + + G F C P G P CH P G
Sbjct: 946 DCCPQCSDCEHEGRKYEPGESFQPGADPCEVCICEPQPEGP--PSLRCHRRQCPS--LVG 1001
Query: 4307 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 4366
C + G + C A ++ C + G++ + C ++ + CP
Sbjct: 1002 CPPSQLLPPGPQHC-CPTCAEALSNC-SEGLLGSELAPPDPCYTCQCQDLTWLCIHQACP 1059
Query: 4367 A-SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 4425
SCP T P G C C+ + R V A E W
Sbjct: 1060 ELSCPLSERHTPP----GSCCPVCRAPTQSCVHQGREV----------------ASGERW 1099
Query: 4426 ADGTCSQWCRCGPGG---GSLVCTPASCGLGEVCGLLP-SGQHGCQPVSTAECQAWGDPH 4481
TC+ C C G S C+P SCG + L P S C P A C A+GDPH
Sbjct: 1100 TVDTCTS-CSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP-RPASCMAFGDPH 1157
Query: 4482 YVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNH 4541
Y T DG FQG+C Y+L+ CH + +F+V V N+ RG V++T+ V + + +
Sbjct: 1158 YRTFDGRLLHFQGSCSYVLAKDCH-----SGDFSVHVTNDDRGRSGVAWTQEVAVLLGDM 1212
Query: 4542 SLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRV 4601
++ L + VDG VALPF + LL+ L G V++ GL + +DG S V + V
Sbjct: 1213 AVRLLQ--DGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQPGLQVLWDGQSQVEVSV 1270
Query: 4602 PAAYAASLCGLCGNYNQDPADDLKAVGG--KPA------GWQVGGAQGCGECVSKPCPS- 4652
P +Y CGLCGN+N DDL+ G P+ WQV G +PC +
Sbjct: 1271 PGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQVSE----GLWPGRPCSAG 1326
Query: 4653 ----PCTPEQQESFGGPDA-CGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGG 4707
PC + +A CGV+ ++ P + CH +VPP +F C+ D C PG
Sbjct: 1327 REVDPCRAAGYRARREANARCGVLKSS--PFSRCHAVVPPEPFFAACVYDLCAC--GPGS 1382
Query: 4708 -----LCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSH--YELCGDSCPVSCPSLS 4760
LC A+ Y + C+ AG WR P C + CP ++ CG CP +C +
Sbjct: 1383 SADACLCDALEAYASHCRQAGV-TPTWRGPTLCVVGCPLERGFVFDECGPPCPRTCFNQH 1441
Query: 4761 APEG-----CESACREGCVCDAGFVLSGDTCVPVGQC 4792
P G C C GC C AG V C+P C
Sbjct: 1442 IPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 195 bits (495), Expect = 1e-48
Identities = 156/463 (33%), Positives = 205/463 (44%), Gaps = 58/463 (12%)
Query: 1142 YEAC-SYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPP 1200
++AC CPLS P PG C C P SC VHQG
Sbjct: 1055 HQACPELSCPLSERHTP-PGSCCPVCRA----------------PTQSC--VHQGREVAS 1095
Query: 1201 GQTFYPGPGCDSLCHCQEGGLVSCESS-----SCGPHEACQPSGGSL--GCVAVGSSTCQ 1253
G+ + C S C C G V C+S SCGP +A S GS C+ +S C
Sbjct: 1096 GERWTVDT-CTS-CSCM-AGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRPAS-CM 1151
Query: 1254 ASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITV 1313
A GDPHY TFDGR F G+C YVLA+ C + F+V N G V+ T+ + V
Sbjct: 1152 AFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD----FSVHVTNDDRGRSGVAWTQEVAV 1207
Query: 1314 QVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYY 1373
+ + +RL Q VTV+G + LP L + G V++ GL+V +D
Sbjct: 1208 LLGDMAVRLLQ-DGAVTVDGHPVALPF-LQEPLLYVELRGHTVILHAQPGLQVLWDGQSQ 1265
Query: 1374 VRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTP 1433
V V+VPG+Y + CGLCGN+NG +DD Q P G + FGNSW+ P P
Sbjct: 1266 VEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSEAAFGNSWQ---VSEGLWPGRP 1322
Query: 1434 CPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCL 1493
C G E P ++ CG+L S P S CH +V P+ C++DLC
Sbjct: 1323 CSAGRE-VDPCRAAGYRARREANAR--CGVLKS--SPFSRCHAVVPPEPFFAACVYDLCA 1377
Query: 1494 GGGNLS---ILCSNIHAYVSACQAAGGHVEP-WRTETFCPMECPPNSH--YELCADTCSL 1547
G S LC + AY S C+ AG V P WR T C + CP ++ C C
Sbjct: 1378 CGPGSSADACLCDALEAYASHCRQAG--VTPTWRGPTLCVVGCPLERGFVFDECGPPCPR 1435
Query: 1548 GCSALSAP-----PQCQDGCAEGCQCDSGFLYNGQACVPIQQC 1585
C P C C GCQC +G + + C+P + C
Sbjct: 1436 TCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPPEAC 1478
Score = 192 bits (488), Expect = 8e-48
Identities = 144/423 (34%), Positives = 195/423 (46%), Gaps = 41/423 (9%)
Query: 791 GACVP---ASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQ----SCPA 843
G+C P A + C QG ++A G+ W + C C+C T V C+ ++ SC
Sbjct: 1073 GSCCPVCRAPTQSCVHQGREVASGER-WTVDTCTS-CSCMAGT--VRCQSQRCSPLSCGP 1128
Query: 844 GERCSVQNGLLGCYP---DRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAAL 900
+ ++ G C P R +C GDPHY +FDGR F G+C+Y+L C
Sbjct: 1129 DKAPALSPG--SCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD-- 1184
Query: 901 PAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQV 960
F V V N+ RG V++T+ V V + AVR G V VD LPF + +
Sbjct: 1185 --FSVHVTNDDRGRSGVAWTQEVAVLLGDM--AVRLLQDGAVTVDGHPVALPF-LQEPLL 1239
Query: 961 QVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGG 1020
V +G ++ GL V +D ++V VP SY CGLCGNFNG DDL G
Sbjct: 1240 YVELRGHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGL 1299
Query: 1021 QAANALAFGNSWQ--EETRPG--CGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFR 1076
+ AFGNSWQ E PG C A D + A++ ++ CG+L PF
Sbjct: 1300 LLPSEAAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARR-EANARCGVL--KSSPFS 1356
Query: 1077 ECHSKLDPQGAVRDCVYDRCLL-PGQSGP--LCDALATYAAACQAAGATVHPWRSEELCP 1133
CH+ + P+ CVYD C PG S LCDAL YA+ C+ AG T WR LC
Sbjct: 1357 RCHAVVPPEPFFAACVYDLCACGPGSSADACLCDALEAYASHCRQAGVT-PTWRGPTLCV 1415
Query: 1134 LSCPPHSH--YEACSYGCPLSCGDLPVPGG-----CGSECHEGCVCDEGFALSGESCLPL 1186
+ CP ++ C CP +C + +P G C C GC C G C+P
Sbjct: 1416 VGCPLERGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEAHCIPP 1475
Query: 1187 ASC 1189
+C
Sbjct: 1476 EAC 1478
Score = 51.2 bits (121), Expect = 3e-05
Identities = 68/227 (29%), Positives = 81/227 (35%), Gaps = 40/227 (17%)
Query: 1071 PKGPFRECHSKL-DPQGAVRDCVYDRC----LLPGQSGPLCDALATYAAACQAAGATVHP 1125
P P R C + Q R CV C LLPG+ P C A A C GA H
Sbjct: 558 PSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQCPA----PAGCPRPGAA-HA 612
Query: 1126 WRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLP 1185
E P P C G +SC LP P + +G C
Sbjct: 613 RHQEYFSPPGDPCRRCL--CLDGS-VSCQRLPCPPAPCAHPRQGPCCP------------ 657
Query: 1186 LASC-GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSL-- 1242
SC GC++QG G+ F LC C EG VSCE +C P P+ G
Sbjct: 658 --SCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKACAPALCPFPARGDCCP 714
Query: 1243 ---GCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRP 1286
GC +G S P D R + TC+ TCG RP
Sbjct: 715 DCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGRRP 755
Score = 50.8 bits (120), Expect = 4e-05
Identities = 80/302 (26%), Positives = 103/302 (34%), Gaps = 72/302 (23%)
Query: 2239 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 2283
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
Query: 2284 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLREWRRPDFCPFQCPAH 2340
P C A + +P G P+ + C + Q R P CP
Sbjct: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
Query: 2341 SHYELCGDSCPGSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 2383
L G+ CP CP AP GC CR C+C G V
Sbjct: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
Query: 2384 CVPVGQC-------------GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 2430
P C GCL+ + + G+ F LC C EG VSCEP +C
Sbjct: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKAC 699
Query: 2431 GPHETCRPSGGSL-----GCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGT 2485
P P+ G GC +G + P D R + TC+ TCG
Sbjct: 700 APALCPFPARGDCCPDCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGR 753
Query: 2486 RP 2487
RP
Sbjct: 754 RP 755
Score = 50.8 bits (120), Expect = 4e-05
Identities = 57/229 (24%), Positives = 85/229 (37%), Gaps = 21/229 (9%)
Query: 5166 GVCIPVQDC---GCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVK 5222
G C PV C H GR + C+ CSC + + + CQ+ C P K
Sbjct: 1073 GSCCPVCRAPTQSCVHQGREVASGERWTVDTCTS-CSCMAGT-VRCQSQRCSPLSCGPDK 1130
Query: 5223 AEARN-------CWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWY 5275
A A + C C+ + TFDG Y L+ C ++
Sbjct: 1131 APALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGDFSVH-- 1188
Query: 5276 RVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLP--AEKLASVSVSRT 5333
V +V + D V L + V V+G V LP E L V +
Sbjct: 1189 --VTNDDRGRSGVAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELR-- 1244
Query: 5334 PDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTND 5382
++++ + G+QV +V V V + G+ CG CGNF+G +D
Sbjct: 1245 -GHTVILHAQPGLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDD 1292
Score = 50.1 bits (118), Expect = 6e-05
Identities = 77/297 (25%), Positives = 93/297 (31%), Gaps = 70/297 (23%)
Query: 2243 CVSKPCPSP------CTPE----------------QQESFGGP-DACGVISATDG----- 2274
CV PCP P C P+ QE F P D C DG
Sbjct: 579 CVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQ 638
Query: 2275 ----PLAPC-HGLVPPA-QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWR 2328
P APC H P GCL + P A ++ C
Sbjct: 639 RLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKA 698
Query: 2329 -RPDFCPFQ-----CPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG- 2381
P CPF CP E G+S + E C C C GFV G
Sbjct: 699 CAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNL-----CTCLGGFVTCGR 753
Query: 2382 ---------DTCVPVGQC-----GCLHDDRYYPLGQTFYP--GPGCDSLCRCREGGEVSC 2425
+P G C GC + G+T P C SLC C+EG + C
Sbjct: 754 RPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGS-MRC 811
Query: 2426 EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDF-MGTCVYVLAQ 2481
+ C P PS G C S C + G H DG F+ G+C + Q
Sbjct: 812 QKKPCPPALCPHPSPGPCFCPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
Score = 50.1 bits (118), Expect = 6e-05
Identities = 77/297 (25%), Positives = 93/297 (31%), Gaps = 70/297 (23%)
Query: 3444 CVSKPCPSP------CTPE----------------QQESFGGP-DACGVISATDG----- 3475
CV PCP P C P+ QE F P D C DG
Sbjct: 579 CVPLPCPEPVLLPGECCPQCPAPAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQ 638
Query: 3476 ----PLAPC-HGLVPPA-QYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWR 3529
P APC H P GCL + P A ++ C
Sbjct: 639 RLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKA 698
Query: 3530 -RPDFCPFQ-----CPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSG- 3582
P CPF CP E G+S + E C C C GFV G
Sbjct: 699 CAPALCPFPARGDCCPDCDGCEYLGESYLSNQEFPDPREPCNL-----CTCLGGFVTCGR 753
Query: 3583 ---------DTCVPVGQC-----GCLHDDRYYPLGQTFYP--GPGCDSLCRCREGGEVSC 3626
+P G C GC + G+T P C SLC C+EG + C
Sbjct: 754 RPCEPPGCSHPLIPSGHCCPTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGS-MRC 811
Query: 3627 EPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDF-MGTCVYVLAQ 3682
+ C P PS G C S C + G H DG F+ G+C + Q
Sbjct: 812 QKKPCPPALCPHPSPGPCFCPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
Score = 48.9 bits (115), Expect = 1e-04
Identities = 79/302 (26%), Positives = 102/302 (33%), Gaps = 72/302 (23%)
Query: 3440 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 3484
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
Query: 3485 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLREWRRPDFCPFQCPAH 3541
P C A + +P G P+ + C + Q R P CP
Sbjct: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
Query: 3542 SHYELCGDSCPGSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 3584
L G+ CP CP AP GC CR C+C G V
Sbjct: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
Query: 3585 CVPVGQC-------------GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSC 3631
P C GCL+ + + G+ F LC C EG VSCEP +C
Sbjct: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSCEPKAC 699
Query: 3632 GPHETCRPSGGSL-----GCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGT 3686
P P+ G GC +G + P D + TC+ TCG
Sbjct: 700 APALCPFPARGDCCPDCDGCEYLGESYLSNQEFP-----DPREPCNLCTCLGGFV-TCGR 753
Query: 3687 RP 3688
RP
Sbjct: 754 RP 755
Score = 47.4 bits (111), Expect = 4e-04
Identities = 49/191 (25%), Positives = 66/191 (34%), Gaps = 56/191 (29%)
Query: 1098 LPGQSGPLCDALATYAAACQAAGATVHPWRSEE--------LCPLSCPPHSHYEACS-YG 1148
+PGQ P+CD C+ G H ++S+E LC + C + +C
Sbjct: 299 IPGQCCPVCDG-------CEYQG---HQYQSQETFRLQERGLC-VRCSCQAGEVSCEEQE 347
Query: 1149 CPLSCGDLPVPG-----GC---GSECHEG------------CVCDEGFALSGESCLPLAS 1188
CP++ LP G C G E EG CVC +G G P A
Sbjct: 348 CPVTPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAP 407
Query: 1189 C---------------GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHE 1233
C C + + GQ F CHCQ+ G V+C C P
Sbjct: 408 CQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQD-GTVTCSLVDCPPTT 466
Query: 1234 ACQPSGGSLGC 1244
+P G C
Sbjct: 467 CARPQSGPGQC 477
Score = 47.4 bits (111), Expect = 4e-04
Identities = 60/242 (24%), Positives = 87/242 (35%), Gaps = 28/242 (11%)
Query: 3829 PCLPPPTCPPGSAGCIPS-DKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLK 3887
PC P P P C PS D C YQ +EF P+ P ++CH + +G +
Sbjct: 641 PCPPAPCAHPRQGPCCPSCDGC------LYQGKEFASGERFPS-PTAACHLCLCWEGSVS 693
Query: 3888 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTC 3947
C LC A C G + E++ N + + C
Sbjct: 694 ------CEPKACAPALCP-FPARGDCCPDCDGC--EYLGESYL-----SNQEFPDPREPC 739
Query: 3948 SLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVL--ID 4005
+L C+ L + C E C + +G C Q GC ++GV +T+ +D
Sbjct: 740 NL-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ--GCRYHGVTTASGETLPDPLD 796
Query: 4006 NCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQG 4065
CTC G + CQ+ C P PS G C C Q+ + +G G
Sbjct: 797 PTCSLCTCQEGSMR-CQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAG 855
Query: 4066 VC 4067
C
Sbjct: 856 SC 857
Score = 46.6 bits (109), Expect = 7e-04
Identities = 65/258 (25%), Positives = 83/258 (32%), Gaps = 53/258 (20%)
Query: 2238 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 2297
+G C KPCP P GP C V CH + + Q D
Sbjct: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
Query: 2298 QVQGHPGGLCP-------AVATYVAACQAAGAQLREWRRPDFCPF--QCPAHSHYELCGD 2348
+ +G P G C V+ C +L+ R CP C AH G
Sbjct: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
Query: 2349 SC---PGSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDDRYYPLGQ 2403
+C S EG + R C+ G C P QC C H+ R Y G+
Sbjct: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
Query: 2404 TFYPGPGCDSLCRCREGGE---------------VSCEPSSC---GPHETCRPSGGSLGC 2445
+F PG +C C E V C PS GP C +L
Sbjct: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSN 1025
Query: 2446 VAVGSTTCQ-ASGDPHYT 2462
+ G + A DP YT
Sbjct: 1026 CSEGLLGSELAPPDPCYT 1043
Score = 46.6 bits (109), Expect = 7e-04
Identities = 65/258 (25%), Positives = 83/258 (32%), Gaps = 53/258 (20%)
Query: 3439 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 3498
+G C KPCP P GP C V CH + + Q D
Sbjct: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
Query: 3499 QVQGHPGGLCP-------AVATYVAACQAAGAQLREWRRPDFCPF--QCPAHSHYELCGD 3549
+ +G P G C V+ C +L+ R CP C AH G
Sbjct: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
Query: 3550 SC---PGSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDDRYYPLGQ 3604
+C S EG + R C+ G C P QC C H+ R Y G+
Sbjct: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
Query: 3605 TFYPGPGCDSLCRCREGGE---------------VSCEPSSC---GPHETCRPSGGSLGC 3646
+F PG +C C E V C PS GP C +L
Sbjct: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQLLPPGPQHCCPTCAEALSN 1025
Query: 3647 VAVGSTTCQ-ASGDPHYT 3663
+ G + A DP YT
Sbjct: 1026 CSEGLLGSELAPPDPCYT 1043
Score = 46.6 bits (109), Expect = 7e-04
Identities = 67/243 (27%), Positives = 82/243 (33%), Gaps = 46/243 (18%)
Query: 4640 QGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC 4699
+G C KPCP P GP C V CH + + Q D
Sbjct: 806 EGSMRCQKKPCPPALCPHPSP---GPCFCPV----------CHSCLSQGREHQ----DGE 848
Query: 4700 QVQGHPGGLCP-------AVATYVAACQAAGAQLGEWRRPDFCPL--QCPAHSHYELCGD 4750
+ +G P G C V+ C +L R CP C AH G
Sbjct: 849 EFEG-PAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGS 907
Query: 4751 SC---PVSCPSLSAPEGCESACREGCVCDAGFVLSGD-TCVPVGQCG-CLHDGRYYPLGE 4805
+C S EG + R C+ G C P QC C H+GR Y GE
Sbjct: 908 RWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP--QCSDCEHEGRKYEPGE 965
Query: 4806 VFYPGPE-CE-RRCECGPGGHVT-------CQEGAACGPHEECRLEDGVQACHATGCGRC 4856
F PG + CE CE P G + C C P + L G Q C T C
Sbjct: 966 SFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPSQ--LLPPGPQHCCPT-CAEA 1022
Query: 4857 LAN 4859
L+N
Sbjct: 1023 LSN 1025
Score = 45.8 bits (107), Expect = 0.001
Identities = 66/252 (26%), Positives = 89/252 (35%), Gaps = 48/252 (19%)
Query: 1427 PCLPPTPCP-PGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLK 1485
PC PP PC P C PS C L YQ +EF P+ P ++CH
Sbjct: 641 PC-PPAPCAHPRQGPCCPS--CDGCL---YQGKEFASGERFPS-PTAACHLC-------- 685
Query: 1486 DCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECP----------PN 1535
LC G S+ C AC A + P+ C +C N
Sbjct: 686 -----LCWEG---SVSCEP-----KACAPA---LCPFPARGDCCPDCDGCEYLGESYLSN 729
Query: 1536 SHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYE 1595
+ + C+L C+ L C E C + +G C Q GC ++GV
Sbjct: 730 QEFPDPREPCNL-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ--GCRYHGVTTA 786
Query: 1596 PEQTVL--IDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQ 1653
+T+ +D CTC G M CQ+ C P PS G C C Q
Sbjct: 787 SGETLPDPLDPTCSLCTCQEGS-MRCQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQ 845
Query: 1654 ETCKEQGGQGVC 1665
+ + +G G C
Sbjct: 846 DGEEFEGPAGSC 857
Score = 43.1 bits (100), Expect = 0.007
Identities = 63/256 (24%), Positives = 75/256 (29%), Gaps = 71/256 (27%)
Query: 2245 SKPCPSPCTP------------EQQESFGGPDACGVISATDG---------PLAPC-HGL 2282
++P P C P E G D C +G P PC H
Sbjct: 238 ARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPG 297
Query: 2283 VPPAQYFQGCLLDACQVQGHP-----------GGLCPAVATYVAACQAAGAQLREWRRPD 2331
P Q C D C+ QGH GLC +CQA E P
Sbjct: 298 KIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGLCVR-----CSCQAGEVSCEEQECP- 349
Query: 2332 FCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE-------GCVCDAGFVLSGDTC 2384
P PA S +LC +C L E E E CVC G G
Sbjct: 350 VTPCALPA-SGRQLC-PAC-----ELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVL 402
Query: 2385 VPVGQC---------------GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS 2429
P C C + + Y GQ F C C++G V+C
Sbjct: 403 CPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDG-TVTCSLVD 461
Query: 2430 CGPHETCRPSGGSLGC 2445
C P RP G C
Sbjct: 462 CPPTTCARPQSGPGQC 477
Score = 43.1 bits (100), Expect = 0.007
Identities = 63/256 (24%), Positives = 75/256 (29%), Gaps = 71/256 (27%)
Query: 3446 SKPCPSPCTP------------EQQESFGGPDACGVISATDG---------PLAPC-HGL 3483
++P P C P E G D C +G P PC H
Sbjct: 238 ARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPG 297
Query: 3484 VPPAQYFQGCLLDACQVQGHP-----------GGLCPAVATYVAACQAAGAQLREWRRPD 3532
P Q C D C+ QGH GLC +CQA E P
Sbjct: 298 KIPGQCCPVC--DGCEYQGHQYQSQETFRLQERGLCVR-----CSCQAGEVSCEEQECP- 349
Query: 3533 FCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACRE-------GCVCDAGFVLSGDTC 3585
P PA S +LC +C L E E E CVC G G
Sbjct: 350 VTPCALPA-SGRQLC-PAC-----ELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVL 402
Query: 3586 VPVGQC---------------GCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSS 3630
P C C + + Y GQ F C C++G V+C
Sbjct: 403 CPPAPCQHPTQPPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDG-TVTCSLVD 461
Query: 3631 CGPHETCRPSGGSLGC 3646
C P RP G C
Sbjct: 462 CPPTTCARPQSGPGQC 477
Score = 42.7 bits (99), Expect = 0.010
Identities = 59/241 (24%), Positives = 86/241 (35%), Gaps = 26/241 (10%)
Query: 2628 PCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKD 2687
PC P P P C PS C L YQ +EF P+ P ++CH + +G +
Sbjct: 641 PCPPAPCAHPRQGPCCPS--CDGCL---YQGKEFASGERFPS-PTAACHLCLCWEGSVS- 693
Query: 2688 CIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCS 2747
C LC A C G + E++ N + + C+
Sbjct: 694 -----CEPKACAPALCP-FPARGDCCPDCDGC--EYLGESYL-----SNQEFPDPREPCN 740
Query: 2748 LGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVL--IDN 2805
L C+ L + C E C + +G C Q GC ++G +T+ +D
Sbjct: 741 L-CTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ--GCRYHGVTTASGETLPDPLDP 797
Query: 2806 CRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGV 2865
CTC G + CQ+ C P PS G C C Q+ + +G G
Sbjct: 798 TCSLCTCQEGSMR-CQKKPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGS 856
Query: 2866 C 2866
C
Sbjct: 857 C 857
Score = 42.7 bits (99), Expect = 0.010
Identities = 60/218 (27%), Positives = 75/218 (34%), Gaps = 45/218 (20%)
Query: 1094 DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELC------PLSCPPHSHYEACSY 1147
D CL G+ + + AAC W C P CP + + C
Sbjct: 660 DGCLYQGKEFASGERFPSPTAACHLCLC----WEGSVSCEPKACAPALCPFPARGDCCPD 715
Query: 1148 --GCP------LSCGDLPVP----------GG---CGSECHEGCVCDEGFALSGESCLPL 1186
GC LS + P P GG CG E C SG C
Sbjct: 716 CDGCEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCC--- 772
Query: 1187 ASC-GCVHQGTYHPPGQTFYP--GPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1243
+C GC + G G+T P C SLC CQEG + C+ C P PS G
Sbjct: 773 PTCQGCRYHGVTTASGETLPDPLDPTC-SLCTCQEGSM-RCQKKPCPPALCPHPSPGPCF 830
Query: 1244 CVAVGSSTCQASGDPHYTTFDGRRFDF-MGTCVYVLAQ 1280
C S C + G H DG F+ G+C + Q
Sbjct: 831 CPVCHS--CLSQGREHQ---DGEEFEGPAGSCEWCRCQ 863
Score = 42.4 bits (98), Expect = 0.013
Identities = 70/267 (26%), Positives = 86/267 (32%), Gaps = 61/267 (22%)
Query: 2236 GAQGCGECVSKPCPSPCTPEQQESFGG----PDACGVISATDGPLAPCHGLVPPAQYFQG 2291
GA CG P C+ Q G PDAC G + C G P+
Sbjct: 122 GAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQ-CQG---PSCSELN 177
Query: 2292 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP-DFCPFQCPAHSHYELCGDSC 2350
CL ++C PG CP T + G +EW P D C H + C
Sbjct: 178 CL-ESCTP---PGECCPICCTEGGSHWEHG---QEWTTPGDPCRICRCLEGHIQCRQREC 230
Query: 2351 PGSCPSLSAP---------EGCESACREG--------------CVCDAGFVLSGDT-CVP 2386
CP + P +GC RE C C G V C P
Sbjct: 231 ASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPP 290
Query: 2387 V---------GQC-----GCLHDDRYYPLGQTF-YPGPGCDSLCRCREGGEVSCEPSSCG 2431
V GQC GC + Y +TF G C C + GEVSCE C
Sbjct: 291 VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSC-QAGEVSCEEQECP 349
Query: 2432 PHETCRPSGGSLGCVAVGSTTCQASGD 2458
P+ G C A C+ G+
Sbjct: 350 VTPCALPASGRQLCPA-----CELDGE 371
Score = 42.4 bits (98), Expect = 0.013
Identities = 70/267 (26%), Positives = 86/267 (32%), Gaps = 61/267 (22%)
Query: 3437 GAQGCGECVSKPCPSPCTPEQQESFGG----PDACGVISATDGPLAPCHGLVPPAQYFQG 3492
GA CG P C+ Q G PDAC G + C G P+
Sbjct: 122 GAAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTTCRCLTGAVQ-CQG---PSCSELN 177
Query: 3493 CLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRP-DFCPFQCPAHSHYELCGDSC 3551
CL ++C PG CP T + G +EW P D C H + C
Sbjct: 178 CL-ESCTP---PGECCPICCTEGGSHWEHG---QEWTTPGDPCRICRCLEGHIQCRQREC 230
Query: 3552 PGSCPSLSAP---------EGCESACREG--------------CVCDAGFVLSGDT-CVP 3587
CP + P +GC RE C C G V C P
Sbjct: 231 ASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPP 290
Query: 3588 V---------GQC-----GCLHDDRYYPLGQTF-YPGPGCDSLCRCREGGEVSCEPSSCG 3632
V GQC GC + Y +TF G C C + GEVSCE C
Sbjct: 291 VPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSC-QAGEVSCEEQECP 349
Query: 3633 PHETCRPSGGSLGCVAVGSTTCQASGD 3659
P+ G C A C+ G+
Sbjct: 350 VTPCALPASGRQLCPA-----CELDGE 371
Score = 42.4 bits (98), Expect = 0.013
Identities = 68/257 (26%), Positives = 87/257 (33%), Gaps = 52/257 (20%)
Query: 4214 CGLCGNMDRNPNNDQVFPNGTLAPSIPI-WGGSWR------APGWDPL-----CWDECRG 4261
C C + + + FP+ T A + + W GS AP P C +C G
Sbjct: 659 CDGCLYQGKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPALCPFPARGDCCPDCDG 718
Query: 4262 SCPTCPEDRLEQYEGPGFCGPLSSGTG-GPFTTCHAHV--PPESFFKGCVLDVCMGGGDR 4318
C E L E P P + T G F TC PP GC + + G
Sbjct: 719 -CEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPP-----GCSHPL-IPSGHC 771
Query: 4319 DILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTP 4378
C+ Y A+G + D TC E S P PA CP P+P
Sbjct: 772 CPTCQG-CRYHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP---- 826
Query: 4379 AVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGP 4438
GPC C ++ C + G H+ G EF +WCRC
Sbjct: 827 ----GPCF---------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQA 864
Query: 4439 GGGSLV---CTPASCGL 4452
G S V C P C L
Sbjct: 865 GQVSCVRLQCPPLPCKL 881
Score = 41.2 bits (95), Expect = 0.028
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 31/124 (25%)
Query: 3150 TCPENSHYEVCGPP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 3199
+C E + E C PP CP C TTP PC C+C G +
Sbjct: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
Query: 3200 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 3245
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
Query: 3246 PASC 3249
P C
Sbjct: 285 PLPC 288
Score = 41.2 bits (95), Expect = 0.028
Identities = 38/124 (30%), Positives = 46/124 (37%), Gaps = 31/124 (25%)
Query: 4351 TCPENSHYEVCGPP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 4400
+C E + E C PP CP C TTP PC C+C G +
Sbjct: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
Query: 4401 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 4446
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
Query: 4447 PASC 4450
P C
Sbjct: 285 PLPC 288
Score = 41.2 bits (95), Expect = 0.028
Identities = 36/128 (28%), Positives = 44/128 (34%), Gaps = 29/128 (22%)
Query: 3127 YVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVE 3186
Y A+G + D TC E S P PA CP P+P GPC
Sbjct: 780 YHGVTTASGETLPDPLDPTCSLCTCQEGSMRCQKKPCPPALCPHPSP--------GPCF- 830
Query: 3187 GCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV--- 3243
C ++ C + G H+ G EF +WCRC G S V
Sbjct: 831 --------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
Query: 3244 CTPASCGL 3251
C P C L
Sbjct: 874 CPPLPCKL 881
Score = 40.8 bits (94), Expect = 0.037
Identities = 37/129 (28%), Positives = 45/129 (34%), Gaps = 31/129 (24%)
Query: 1926 YVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCP-ASCPSPAPLTTPAVCEGPCV 1984
Y A+G + D TC E S PCP A CP P+P GPC
Sbjct: 780 YHGVTTASGETLPDPLDPTCSLCTCQEGS-MRCQKKPCPPALCPHPSP--------GPCF 830
Query: 1985 EGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLV-- 2042
C ++ C + G H+ G EF +WCRC G S V
Sbjct: 831 ---------------CPVCHS---CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRL 872
Query: 2043 -CTPASCGL 2050
C P C L
Sbjct: 873 QCPPLPCKL 881
Score = 40.0 bits (92), Expect = 0.063
Identities = 65/256 (25%), Positives = 77/256 (30%), Gaps = 71/256 (27%)
Query: 1040 CGATEPGDC-PKLDSL--VAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRC 1096
C GDC P D + + S E DP+ P C G C C
Sbjct: 704 CPFPARGDCCPDCDGCEYLGESYLSNQE---FPDPREPCNLCTCL----GGFVTCGRRPC 756
Query: 1097 LLPGQSGPLCDA--LATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYG------ 1148
PG S PL + C+ G T S E P P C G
Sbjct: 757 EPPGCSHPLIPSGHCCPTCQGCRYHGVTT---ASGETLPDPLDPTCSLCTCQEGSMRCQK 813
Query: 1149 --CPLSCGDLPVPGGCGSE-CH----------------------EGCVCDEG-FALSGES 1182
CP + P PG C CH E C C G +
Sbjct: 814 KPCPPALCPHPSPGPCFCPVCHSCLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQ 873
Query: 1183 CLPL---------ASC-----GCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSS 1228
C PL SC GC+ G HP G + P S C C E G+V+C
Sbjct: 874 CPPLPCKLQVTERGSCCPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHE-GVVTCARIQ 932
Query: 1229 C---------GPHEAC 1235
C GPH+ C
Sbjct: 933 CISSCAQPRQGPHDCC 948
Score = 38.1 bits (87), Expect = 0.24
Identities = 37/124 (29%), Positives = 45/124 (36%), Gaps = 31/124 (25%)
Query: 1949 TCPENSHYEVCGSP---CPASCPSPAP-------LTTPAVCEGPCVEGCQCDAGFVLSAD 1998
+C E + E C P CP C TTP PC C+C G +
Sbjct: 172 SCSELNCLESCTPPGECCPICCTEGGSHWEHGQEWTTPG---DPC-RICRCLEGHIQCRQ 227
Query: 1999 R-CV--------PLNNGC-----GCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCT 2044
R C PL C GC+ NG H +G + CS CRC GS+ C
Sbjct: 228 RECASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSH-CRC--ANGSVQCE 284
Query: 2045 PASC 2048
P C
Sbjct: 285 PLPC 288
Score = 38.1 bits (87), Expect = 0.24
Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 15/97 (15%)
Query: 1156 LPVPGGCGS-ECHEGCV-CDEGFALSG--------ESCLPLASCGCVHQGTYHPPGQTFY 1205
+P C S CHEG V C +S C P S C H+G + PG++F
Sbjct: 910 VPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCPQCS-DCEHEGRKYEPGESFQ 968
Query: 1206 PGPGCDSLCHCQ---EG-GLVSCESSSCGPHEACQPS 1238
PG +C C+ EG + C C C PS
Sbjct: 969 PGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPS 1005
Score = 37.7 bits (86), Expect = 0.31
Identities = 65/243 (26%), Positives = 82/243 (33%), Gaps = 62/243 (25%)
Query: 4641 GCGECVSKPCPSPCTPEQQ-----ESFGGP-DACGVISATDG---------PLAPCHGLV 4685
G G+C + CP C E++ ESF P D C +G P APC +
Sbjct: 473 GPGQCCPR-CPD-CILEEEVFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRAPCAHPL 530
Query: 4686 PPAQYFQGCLLDACQVQGHPGGLC---PAVATYVAACQAAGAQLGEWRRPDFCPLQCPAH 4742
P C A + +P G P+ + C + Q R PL CP
Sbjct: 531 PGTCCPNDCSGCAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARR---CVPLPCP-- 585
Query: 4743 SHYELCGDSCPVSCPSLSAPEGCE-----------------SACREGCVCDAGFVLSGDT 4785
L G+ CP CP AP GC CR C+C G V
Sbjct: 586 EPVLLPGECCP-QCP---APAGCPRPGAAHARHQEYFSPPGDPCRR-CLCLDGSVSCQRL 640
Query: 4786 CVPVGQC-------------GCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAA 4832
P C GCL+ G+ + GE F C C G V+C E A
Sbjct: 641 PCPPAPCAHPRQGPCCPSCDGCLYQGKEFASGERFPSPTAACHLCLCWEGS-VSC-EPKA 698
Query: 4833 CGP 4835
C P
Sbjct: 699 CAP 701
Score = 37.0 bits (84), Expect = 0.53
Identities = 55/194 (28%), Positives = 70/194 (36%), Gaps = 38/194 (19%)
Query: 1071 PKGPFREC-----HSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHP 1125
P P R C H + + C Y LPG P+CD C G
Sbjct: 209 PGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVCDG-------CFLNG---RE 258
Query: 1126 WRSEELCPL-SCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCL 1184
RS E P+ S P SH C+ G + C LP P C + G+ C
Sbjct: 259 HRSGE--PVGSGDPCSHCR-CANGS-VQCEPLPCPP---------VPCRHPGKIPGQCC- 304
Query: 1185 PLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLG 1243
P+ GC +QG + +TF G C CQ G VSCE C P+ G
Sbjct: 305 PVCD-GCEYQGHQYQSQETFRLQERGLCVRCSCQAGE-VSCEEQECPVTPCALPASGRQL 362
Query: 1244 CVAVGSSTCQASGD 1257
C A C+ G+
Sbjct: 363 CPA-----CELDGE 371
Score = 36.2 bits (82), Expect = 0.91
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 16/108 (14%)
Query: 4762 PEGCE---SACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818
PEG AC CVC G G GC +G+ Y GE F P+ C
Sbjct: 104 PEGARWEPDACT-ACVCQDGAAHCGPQAHLPHCRGCSQNGQTYGNGETF--SPDACTTCR 160
Query: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATG--CGRCLANGGIHY 4864
C G V CQ GP C + +++C G C C GG H+
Sbjct: 161 CLTGA-VQCQ-----GP--SCSELNCLESCTPPGECCPICCTEGGSHW 200
Score = 35.8 bits (81), Expect = 1.2
Identities = 118/496 (23%), Positives = 154/496 (31%), Gaps = 95/496 (19%)
Query: 4389 CQCDAGFVLSADRCVP---LNNGCGCWANGTYHEAGSEFWADGTCSQWCRC--------G 4437
C C G A C P L + GC NG + G F D + CRC G
Sbjct: 117 CVCQDG----AAHCGPQAHLPHCRGCSQNGQTYGNGETFSPDACTT--CRCLTGAVQCQG 170
Query: 4438 PGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT--LDGHRFDFQGT 4495
P L C + GE C + + + G E GDP + L+GH Q
Sbjct: 171 PSCSELNCLESCTPPGECCPICCT-EGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRE 229
Query: 4496 CEYLLSAPCHGPP---LGAENFTVTVANEHRGSQAV------SYTRSVTLQIYNHSLT-- 4544
C L P P + EHR + V S+ R + L
Sbjct: 230 CASLCPYPARPLPGTCCPVCDGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCP 289
Query: 4545 -LSARWPRKLQ------VDGV-FVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSF 4596
+ R P K+ DG + +Q G V + +G + +
Sbjct: 290 PVPCRHPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVSCEEQECP 349
Query: 4597 VRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTP 4656
V P A AS LC D + + V +P G + C CV +
Sbjct: 350 V---TPCALPASGRQLCPACELDGEEFAEGVQWEPDG------RPCTACVCQD------- 393
Query: 4657 EQQESFGGPDACGVISATDGPLAPC-HGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATY 4715
G CG + P APC H PP C D+C
Sbjct: 394 -------GVPKCGAVLC---PPAPCQHPTQPPGACCPSC--DSCTYHSQVYANGQNFTDA 441
Query: 4716 VAACQAAGAQLGE------------WRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAP- 4762
+ C A Q G RP P QC + + V S S P
Sbjct: 442 DSPCHACHCQDGTVTCSLVDCPPTTCARPQSGPGQCCPRCPDCILEEEVFVDGESFSHPR 501
Query: 4763 EGC-ESACREGCV---------CDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF-YPGP 4811
+ C E C+EG L G TC P GC G+ YP G F +P
Sbjct: 502 DPCQECRCQEGHAHCQPRPCPRAPCAHPLPG-TCCPNDCSGCAFGGKEYPSGADFPHPSD 560
Query: 4812 ECERRCECGPGGHVTC 4827
C R C C G+V C
Sbjct: 561 PC-RLCRC-LSGNVQC 574
Score = 35.4 bits (80), Expect = 1.5
Identities = 63/240 (26%), Positives = 79/240 (32%), Gaps = 55/240 (22%)
Query: 1027 AFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQG 1086
A G W+ + RP PK CG + P P C P G
Sbjct: 374 AEGVQWEPDGRPCTACVCQDGVPK--------------CGAVLCPPAP---CQHPTQPPG 416
Query: 1087 AV----RDCVY-DRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCP-PHS 1140
A C Y + GQ+ D+ +A CQ T + P +C P S
Sbjct: 417 ACCPSCDSCTYHSQVYANGQNFTDADS-PCHACHCQDGTVTCS---LVDCPPTTCARPQS 472
Query: 1141 HYEACSYGCPLSC---GDLPVPGGCGSE----CHEGCVCDEGFA---------------L 1178
C CP C ++ V G S C E C C EG A L
Sbjct: 473 GPGQCCPRCP-DCILEEEVFVDGESFSHPRDPCQE-CRCQEGHAHCQPRPCPRAPCAHPL 530
Query: 1179 SGESCLPLASCGCVHQGTYHPPGQTF-YPGPGCDSLCHCQEGGLVSCESSSCGPHEACQP 1237
G +C P GC G +P G F +P C LC C G V C + C P +P
Sbjct: 531 PG-TCCPNDCSGCAFGGKEYPSGADFPHPSDPC-RLCRCLSGN-VQCLARRCVPLPCPEP 587
Score = 34.7 bits (78), Expect = 2.6
Identities = 39/152 (25%), Positives = 52/152 (34%), Gaps = 35/152 (23%)
Query: 714 LCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCN----GAAAPS 769
LCR LS Q + + P P+ P C P CP GAA
Sbjct: 564 LCRCLSGNVQCLARRCVPL-----PCPEPVLLPGE-----CCPQCPAPAGCPRPGAAHAR 613
Query: 770 NCS-----GRPCVEGCVCLPGFVASGGACVPASSC-------------GCTFQGLQLAPG 811
+ G PC C+CL G V+ P + C GC +QG + A G
Sbjct: 614 HQEYFSPPGDPC-RRCLCLDGSVSCQRLPCPPAPCAHPRQGPCCPSCDGCLYQGKEFASG 672
Query: 812 QEVWADELCQRRCTCNGATHQVTCRDKQSCPA 843
+ + C C + V+C K PA
Sbjct: 673 ERFPSPTAACHLCLCWEGS--VSCEPKACAPA 702
Score = 33.9 bits (76), Expect = 4.5
Identities = 49/184 (26%), Positives = 67/184 (36%), Gaps = 42/184 (22%)
Query: 735 WRSPANC-PLSC-PANSRYELCGPACPTSCNGAA--APSNCSGR-------PCVEGCVCL 783
W +C P +C PA + G CP C+G S S + PC C CL
Sbjct: 688 WEGSVSCEPKACAPALCPFPARGDCCP-DCDGCEYLGESYLSNQEFPDPREPC-NLCTCL 745
Query: 784 PGFVASG----------------GACVPASSCGCTFQGLQLAPGQEV--WADELCQRRCT 825
GFV G G C P GC + G+ A G+ + D C CT
Sbjct: 746 GGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQ-GCRYHGVTTASGETLPDPLDPTCS-LCT 803
Query: 826 CNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF-MG 884
C + + C+ K+ CP G C+ +C G H DG F+ G
Sbjct: 804 CQEGS--MRCQ-KKPCPPALCPHPSPG--PCFCPVCHSCLSQGREHQ---DGEEFEGPAG 855
Query: 885 TCTY 888
+C +
Sbjct: 856 SCEW 859
Score = 33.5 bits (75), Expect = 5.9
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 1964 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 2021
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
Query: 2022 FWADGTCSQWCRCGPGGGSLVCTPASC 2048
+ G + CRC G + C C
Sbjct: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
Score = 33.5 bits (75), Expect = 5.9
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 3165 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 3222
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
Query: 3223 FWADGTCSQWCRCGPGGGSLVCTPASC 3249
+ G + CRC G + C C
Sbjct: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
Score = 33.5 bits (75), Expect = 5.9
Identities = 23/87 (26%), Positives = 32/87 (36%), Gaps = 11/87 (12%)
Query: 4366 PASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCG--CWANGTYHEAGSE 4423
P +C + LT C+GP C + C P C C G++ E G E
Sbjct: 153 PDACTTCRCLTGAVQCQGPSCSELNC-------LESCTPPGECCPICCTEGGSHWEHGQE 205
Query: 4424 FWADGTCSQWCRCGPGGGSLVCTPASC 4450
+ G + CRC G + C C
Sbjct: 206 WTTPGDPCRICRCLE--GHIQCRQREC 230
>gi|37693519 BMP-binding endothelial regulator precursor protein [Homo
sapiens]
Length = 685
Score = 187 bits (476), Expect = 2e-46
Identities = 131/447 (29%), Positives = 191/447 (42%), Gaps = 41/447 (9%)
Query: 1966 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 2022
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
Query: 2023 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 2075
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
Query: 2076 GDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 2135
GDPHY T DG FNFQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
Query: 2136 IYNHSLTL----SARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 2191
+ ++L + RW +G + LP + H L G + VTT +GL +++DG
Sbjct: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
Query: 2192 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 2243
DSFV + G LCGLCGNYN DDL G W+V + C
Sbjct: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
Query: 2244 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 2303
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
Query: 2304 GGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC 2363
C + Y ACQ G ++ + + QC + Y+ CG C +C + + C
Sbjct: 596 NCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC 655
Query: 2364 ESACREGCVCDAGFVLSGDTCVPVGQC 2390
C GC C A VL C+ C
Sbjct: 656 NKPCVAGCHCPANLVLHKGRCIKPVLC 682
Score = 186 bits (471), Expect = 7e-46
Identities = 130/447 (29%), Positives = 191/447 (42%), Gaps = 41/447 (9%)
Query: 3167 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 3223
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
Query: 3224 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 3276
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
Query: 3277 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 3336
GDPHY T DG F+FQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
Query: 3337 IYNHSLTL----SARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 3392
+ ++L + RW +G + LP + H L G + VTT +GL +++DG
Sbjct: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
Query: 3393 DSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 3444
DSFV + G LCGLCGNYN DDL G W+V + C
Sbjct: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
Query: 3445 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 3504
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
Query: 3505 GGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGC 3564
C + Y ACQ G ++ + + QC + Y+ CG C +C + + C
Sbjct: 596 NCYCESFLAYTRACQREGIKVHWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPC 655
Query: 3565 ESACREGCVCDAGFVLSGDTCVPVGQC 3591
C GC C A VL C+ C
Sbjct: 656 NKPCVAGCHCPANLVLHKGRCIKPVLC 682
Score = 185 bits (469), Expect = 1e-45
Identities = 132/448 (29%), Positives = 191/448 (42%), Gaps = 43/448 (9%)
Query: 4368 SCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRC---VPLNNGCGCWANGTYHEAGSEF 4424
+C + + VC+ C CD G + C VP + C + G E
Sbjct: 255 NCTACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDG-EM 313
Query: 4425 WADGTCSQWCRCGPGGGSL---VCTP-ASCGLGEVCGLLPSGQHGCQPVSTAE---CQAW 4477
W+ C+ C C G C P +SC G++ + GC P+ T + C +
Sbjct: 314 WSSINCTI-CACVKGRTECRNKQCIPISSCPQGKILN-----RKGCCPICTEKPGVCTVF 367
Query: 4478 GDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQ 4537
GDPHY T DG F+FQGTC+Y+L+ C P A F V V N+ R +++ S+T+SV L
Sbjct: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSP---ASPFQVLVKNDARRTRSFSWTKSVELV 424
Query: 4538 IYNHSLTL----SARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDG 4593
+ ++L + RW +G +ALP + H L G + VTT +GL +++DG
Sbjct: 425 LGESRVSLQQHLTVRW------NGSRIALPCRAPHF-HIDLDGYLLKVTTKAGLEISWDG 477
Query: 4594 DSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGK--------PAGWQVGGAQGCGEC 4645
DSFV + LCGLCGNYN DDL G W+V + C
Sbjct: 478 DSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRP 537
Query: 4646 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHP 4705
KP P C + C + + + CH V A +++ C+ D C+ H
Sbjct: 538 QRKPVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHK 595
Query: 4706 GGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAPEG 4764
C + Y ACQ G ++ W C QC + Y+ CG C +C + +
Sbjct: 596 NCYCESFLAYTRACQREGIKV-HWEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
Query: 4765 CESACREGCVCDAGFVLSGDTCVPVGQC 4792
C C GC C A VL C+ C
Sbjct: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
Score = 172 bits (436), Expect = 8e-42
Identities = 141/497 (28%), Positives = 208/497 (41%), Gaps = 65/497 (13%)
Query: 741 CP-LSCPANSRYELCGPACPT-------------SC--------NGAA-APSNCSGRPCV 777
CP LSCP + + G CP SC NG++ NC+ C
Sbjct: 203 CPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLFRSDVYDNGSSFLYDNCTACTCR 262
Query: 778 EGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQ---------------EVWADELCQR 822
+ V + G C GC + L P + E+W+ C
Sbjct: 263 DSTVVCKRKCSHPGGCDQGQE-GCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINCTI 321
Query: 823 RCTCNGATHQVTCRDKQ-----SCPAGERCSVQNGLLGCYP---DRFGTCQGSGDPHYVS 874
G T CR+KQ SCP G+ + + GC P ++ G C GDPHY +
Sbjct: 322 CACVKGRTE---CRNKQCIPISSCPQGKILNRK----GCCPICTEKPGVCTVFGDPHYNT 374
Query: 875 FDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAV 934
FDGR F+F GTC Y+L C A+ F+VLV+N+ R +++ S+T++V + +V++
Sbjct: 375 FDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSL 432
Query: 935 RREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSS 994
++ V + LP +A + + G V T GL +++D ++ V
Sbjct: 433 QQHLT--VRWNGSRIALPCRAPHFHIDL--DGYLLKVTTKAGLEISWDGDSFVEVMAAPH 488
Query: 995 YAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKL-DS 1053
LCGLCGN+NG DDL G + F SW+ E+ C + P+L
Sbjct: 489 LKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVESNEFCNRPQRKPVPELCQG 548
Query: 1054 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1113
V +L++ EC L + F+ CHS +D R CV D C P C++ Y
Sbjct: 549 TVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYT 606
Query: 1114 AACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVC 1172
ACQ G VH W ++ C + C + Y+ C GC +C + G C C GC C
Sbjct: 607 RACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVAGCHC 665
Query: 1173 DEGFALSGESCLPLASC 1189
L C+ C
Sbjct: 666 PANLVLHKGRCIKPVLC 682
Score = 167 bits (422), Expect = 3e-40
Identities = 135/467 (28%), Positives = 203/467 (43%), Gaps = 51/467 (10%)
Query: 3945 DTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACV------PIQQCGCYHNGVYYEP 3998
D C+ C+ + + C C+ CD G + C+ I+ C + N ++ +
Sbjct: 254 DNCT-ACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCK-FGNKIFQDG 311
Query: 3999 EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETC 4058
E I NC C C G+ C+ C P C P G IL+ K C C
Sbjct: 312 EMWSSI-NCTI-CACVKGRTE-CRNKQCIPISSC-PQGKILN--RKGCC--------PIC 357
Query: 4059 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 4118
E+ G C ++GDPHY++FDGR F+FQGTC YVL T C ++ PF
Sbjct: 358 TEKPG----------VCTVFGDPHYNTFDGRTFNFQGTCQYVL-TKDCSSPAS----PFQ 402
Query: 4119 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQ 4178
V KN R + S+ + V + + +S+ + VR NG ALP I +
Sbjct: 403 VLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLT--VRWNGSRIALPCRAPHFHIDLDG 460
Query: 4179 GASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 4238
K A GL++S+D + V+V G +CGLCGN + + +D + +G
Sbjct: 461 YLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFD 518
Query: 4239 IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFCGPLSSGTGGPFTTCHAH 4297
+ + SWR + C R P + ++ + C L S F TCH+
Sbjct: 519 VDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLKSWE---FQTCHST 574
Query: 4298 VPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT-CPENS 4356
V +F++ CV D+C ++ C++ +Y ACQ G+ + W Q C T C +
Sbjct: 575 VDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA 633
Query: 4357 HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 4403
Y+ CGP C +C + + C PCV GC C A VL RC+
Sbjct: 634 VYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHKGRCI 677
Score = 165 bits (418), Expect = 1e-39
Identities = 134/467 (28%), Positives = 202/467 (43%), Gaps = 51/467 (10%)
Query: 2744 DTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACV------PIQQCGCYHNGAYYEP 2797
D C+ C+ + + C C+ CD G + C+ I+ C + N + +
Sbjct: 254 DNCT-ACTCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCK-FGNKIFQDG 311
Query: 2798 EQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETC 2857
E I NC C C G+ C+ C P C P G IL N+ C + C
Sbjct: 312 EMWSSI-NCTI-CACVKGRTE-CRNKQCIPISSC-PQGKIL---NRKGCCPI-------C 357
Query: 2858 KEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFT 2917
E+ G C ++GDPHY++FDGR F+FQGTC YVL T C ++ PF
Sbjct: 358 TEKPG----------VCTVFGDPHYNTFDGRTFNFQGTCQYVL-TKDCSSPAS----PFQ 402
Query: 2918 VTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQ 2977
V KN R + S+ + V + + +S+ + VR NG ALP I +
Sbjct: 403 VLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLT--VRWNGSRIALPCRAPHFHIDLDG 460
Query: 2978 GASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 3037
K A GL++S+D + V+V G +CGLCGN + + +D + +G
Sbjct: 461 YLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFD 518
Query: 3038 IPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFCGPLAPGTGGPFTTCHAH 3096
+ + SWR + C R P + ++ + C L F TCH+
Sbjct: 519 VDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLK---SWEFQTCHST 574
Query: 3097 VPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT-CPENS 3155
V +F++ CV D+C ++ C++ +Y ACQ G+ + W Q C T C +
Sbjct: 575 VDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGA 633
Query: 3156 HYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 3202
Y+ CGP C +C + + C PCV GC C A VL RC+
Sbjct: 634 VYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHKGRCI 677
Score = 165 bits (418), Expect = 1e-39
Identities = 108/363 (29%), Positives = 155/363 (42%), Gaps = 18/363 (4%)
Query: 444 CEGMQCAAGQRC---QVVGGKAGC--VAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTM 498
C QC C +++ K C E VC GDPHY TFDGR ++ GTC Y +
Sbjct: 331 CRNKQCIPISSCPQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDGRTFNFQGTCQYVL 390
Query: 499 VELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSR 558
+ CS + F V KN+ R +R S+ V + VSL + + V SR
Sbjct: 391 TKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQ----HLTVRWNGSR 444
Query: 559 LPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDP 618
+ + + G V GL +++D D + + + ++CGLCGNYNG
Sbjct: 445 IALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHK 504
Query: 619 ADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQ-HYEGDRLCGML 677
DD + DG D +FA SW+++ ++ C + P G + R C L
Sbjct: 505 RDDLIGGDGNFKFDVDDFAESWRVESNEF-CNRPQRKPVPELCQGTVKVKLRAHRECQKL 563
Query: 678 TKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRS 737
+ F CH T+D F CV D+C + C AY +AC GI V W
Sbjct: 564 KSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKV-HWEP 620
Query: 738 PANCPLS-CPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPA 796
NC + C + Y+ CGP C +C+ C+ +PCV GC C V G C+
Sbjct: 621 QQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCN-KPCVAGCHCPANLVLHKGRCIKP 679
Query: 797 SSC 799
C
Sbjct: 680 VLC 682
Score = 162 bits (410), Expect = 8e-39
Identities = 137/469 (29%), Positives = 200/469 (42%), Gaps = 60/469 (12%)
Query: 1541 CADT---CSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVP---IQQCGCYHNGVYY 1594
C D+ C CS Q Q+GC E C VP I+ C + N ++
Sbjct: 261 CRDSTVVCKRKCSHPGGCDQGQEGCCEECLLR----------VPPEDIKVCK-FGNKIFQ 309
Query: 1595 EPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQE 1654
+ E I NC C C G+ C+ C P C P G IL+ K C
Sbjct: 310 DGEMWSSI-NCTI-CACVKGR-TECRNKQCIPISSC-PQGKILN--RKGCC--------P 355
Query: 1655 TCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTP 1714
C E+ G C ++GDPHY++FDGR F+FQGTC YVL T C ++ P
Sbjct: 356 ICTEKPG----------VCTVFGDPHYNTFDGRTFNFQGTCQYVL-TKDCSSPAS----P 400
Query: 1715 FTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISV 1774
F V KN R + S+ + V + + +S+ + VR NG ALP I +
Sbjct: 401 FQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQHLT--VRWNGSRIALPCRAPHFHIDL 458
Query: 1775 TQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLA 1834
K A GL++S+D + V+V G +CGLCGN + + +D + +G
Sbjct: 459 DGYLLKVTTKA--GLEISWDGDSFVEVMAAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFK 516
Query: 1835 PSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLE-QYEGPGFCGPLAPGTGGPFTTCH 1893
+ + SWR + C R P + ++ + C L F TCH
Sbjct: 517 FDVDDFAESWRVES-NEFCNRPQRKPVPELCQGTVKVKLRAHRECQKLK---SWEFQTCH 572
Query: 1894 AHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEIT-CPE 1952
+ V +F++ CV D+C ++ C++ +Y ACQ G+ + W Q C T C
Sbjct: 573 STVDYATFYRSCVTDMCECPVHKNCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKH 631
Query: 1953 NSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV 2001
+ Y+ CG C +C + + C PCV GC C A VL RC+
Sbjct: 632 GAVYDTCGPGCIKTCDNWNEI---GPCNKPCVAGCHCPANLVLHKGRCI 677
Score = 153 bits (387), Expect = 4e-36
Identities = 124/440 (28%), Positives = 185/440 (42%), Gaps = 41/440 (9%)
Query: 4748 CGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVF 4807
C DS V S P GC+ +EGC C+ + + V C + + GE+
Sbjct: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGEM- 313
Query: 4808 YPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC--------GRCLAN 4859
+ C C C G C+ C P C + + GC G C
Sbjct: 314 WSSINCTI-CACVKG-RTECRN-KQCIPISSCPQG---KILNRKGCCPICTEKPGVCTVF 367
Query: 4860 GGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVV 4919
G HY T DGR ++ G+C YVL + C VL KN A + T + ++V
Sbjct: 368 GDPHYNTFDGRTFNFQGTCQYVLTKDCSSPASPFQ---VLVKNDARRTRSFSWTKSVELV 424
Query: 4920 ------SLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMS 4973
SL Q V +G +ALP + +G + + T GL + +DGD+ + +
Sbjct: 425 LGESRVSLQQHLTVRWNGSRIALPCRAPHFHIDLDGYLLKVTTKAGLEISWDGDSFVEVM 484
Query: 4974 IPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGC 5033
+G+LCGLCGN+NG+ DD + +G+ V+ F +WR S++ C PQ
Sbjct: 485 AAPHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWRVE-SNEFCNR---PQRK 540
Query: 5034 PV---CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFL 5090
PV C ++ C +L++ + F TC + + + ++R CV D+C K
Sbjct: 541 PVPELCQGTVKVKLRAHRECQKLKSWE--FQTCHSTVDYATFYRSCVTDMCECPVHKNCY 598
Query: 5091 CRSLAAYTAACQAAGVAVKPWRTDSFC-PLHCPAHSHYSICTRTCQGSCAALSGLTGCTT 5149
C S AYT ACQ G+ V W C C + Y C C +C + + C
Sbjct: 599 CESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNK 657
Query: 5150 RCFEGCECDDRFLLSQGVCI 5169
C GC C +L +G CI
Sbjct: 658 PCVAGCHCPANLVLHKGRCI 677
Score = 151 bits (381), Expect = 2e-35
Identities = 135/501 (26%), Positives = 198/501 (39%), Gaps = 64/501 (12%)
Query: 1130 ELCP-LSCPPHSHYEACSYGCPLSCG-----DLPVPGGC--GSECHEG-----------C 1170
E+CP LSCP H + CP G DLP G C S+ ++ C
Sbjct: 201 EVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPF-GSCLFRSDVYDNGSSFLYDNCTAC 259
Query: 1171 VCDEGFALSGESCLPLASC-----GCVHQGTYHPP----------GQTFYPGPGCDSL-- 1213
C + + C C GC + P + F G S+
Sbjct: 260 TCRDSTVVCKRKCSHPGGCDQGQEGCCEECLLRVPPEDIKVCKFGNKIFQDGEMWSSINC 319
Query: 1214 --CHCQEGGLVSCESSSCGPHEACQPSGGSL---GCVAVGSS---TCQASGDPHYTTFDG 1265
C C +G C + C P +C P G L GC + + C GDPHY TFDG
Sbjct: 320 TICACVKGR-TECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDPHYNTFDG 377
Query: 1266 RRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQR 1325
R F+F GTC YVL + C + F VL +N A S T+ + + + + L+Q
Sbjct: 378 RTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGESRVSLQQH 435
Query: 1326 QWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQ 1385
V NG + LP + I G + + T GL +++D +V V + +
Sbjct: 436 L-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISWDGDSFVEVMAAPHLKGK 492
Query: 1386 MCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSH 1445
+CGLCGNYNG +DD +G+ + ++F SW V + C P P +P
Sbjct: 493 LCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR-VESNEFCNRPQRKP------VPE- 544
Query: 1446 KCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNI 1505
C ++ K + C L S +CH VD + C+ D+C + + C +
Sbjct: 545 LCQGTVKVKLRAHRECQKLKS--WEFQTCHSTVDYATFYRSCVTDMCECPVHKNCYCESF 602
Query: 1506 HAYVSACQAAGGHVEPWRTETFCPM-ECPPNSHYELCADTCSLGCSALSAPPQCQDGCAE 1564
AY ACQ G V W + C +C + Y+ C C C + C C
Sbjct: 603 LAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGPCNKPCVA 661
Query: 1565 GCQCDSGFLYNGQACVPIQQC 1585
GC C + + + C+ C
Sbjct: 662 GCHCPANLVLHKGRCIKPVLC 682
Score = 147 bits (371), Expect = 3e-34
Identities = 124/448 (27%), Positives = 188/448 (41%), Gaps = 33/448 (7%)
Query: 2346 CGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTF 2405
C DS S P GC+ +EGC C+ + + V C ++ + G+
Sbjct: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGE-M 313
Query: 2406 YPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSL---GCVAVGST---TCQASGDP 2459
+ C ++C C +G C C P +C P G L GC + + C GDP
Sbjct: 314 WSSINC-TICACVKG-RTECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDP 370
Query: 2460 HYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 2519
HY TFDGR F+F GTC YVL + C + F VL +N A S T+ + + +
Sbjct: 371 HYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGES 428
Query: 2520 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV 2579
+ L+Q V NG + LP + I G + + T GL +++D +V V
Sbjct: 429 RVSLQQHL-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISWDGDSFVEVMA 485
Query: 2580 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 2639
+ +CGLCGNYNG +DD +G+ + ++F SW V + C P P
Sbjct: 486 APHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR-VESNEFCNRPQRKP--- 541
Query: 2640 EGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 2699
+P E C ++ K + C L S +CH VD + C+ D+C +
Sbjct: 542 ---VP-ELCQGTVKVKLRAHRECQKLKS--WEFQTCHSTVDYATFYRSCVTDMCECPVHK 595
Query: 2700 SILCSNIHAYVSACQAAGGQVEPWRNETFCPM-ECPQNSHYELCADTCSLGCSALSAPLQ 2758
+ C + AY ACQ G +V W + C +C + Y+ C C C +
Sbjct: 596 NCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
Query: 2759 CPDGCAEGCQCDSGFLYNGQACVPIQQC 2786
C C GC C + + + C+ C
Sbjct: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
Score = 144 bits (362), Expect = 3e-33
Identities = 122/448 (27%), Positives = 186/448 (41%), Gaps = 33/448 (7%)
Query: 3547 CGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTF 3606
C DS S P GC+ +EGC C+ + + V C ++ + G+
Sbjct: 261 CRDSTVVCKRKCSHPGGCDQG-QEGC-CEECLLRVPPEDIKV----CKFGNKIFQDGE-M 313
Query: 3607 YPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSL---GCVAVGST---TCQASGDP 3660
+ C ++C C +G C C P +C P G L GC + + C GDP
Sbjct: 314 WSSINC-TICACVKG-RTECRNKQCIPISSC-PQGKILNRKGCCPICTEKPGVCTVFGDP 370
Query: 3661 HYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANF 3720
HY TFDG F+F GTC YVL + C + F VL +N A S T+ + + +
Sbjct: 371 HYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVELVLGES 428
Query: 3721 TLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTV 3780
+ L+Q V NG + LP + I G + + T GL +++D +V V
Sbjct: 429 RVSLQQHL-TVRWNGSRIALPCRAPHFHIDLD--GYLLKVTTKAGLEISWDGDSFVEVMA 485
Query: 3781 PGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS 3840
+ +CGLCGNYNG +DD +G+ + ++F SW V + C P P
Sbjct: 486 APHLKGKLCGLCGNYNGHKRDDLIGGDGNFKFDVDDFAESWR-VESNEFCNRPQRKP--- 541
Query: 3841 AGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNL 3900
+P + C ++ K + C L S +CH VD + C+ D+C +
Sbjct: 542 ---VP-ELCQGTVKVKLRAHRECQKLKS--WEFQTCHSTVDYATFYRSCVTDMCECPVHK 595
Query: 3901 SILCSNIHAYVSACQAAGGHVEPWRNETFCPM-ECPQNSHYELCADTCSLGCSALSAPLQ 3959
+ C + AY ACQ G V W + C +C + Y+ C C C +
Sbjct: 596 NCYCESFLAYTRACQREGIKVH-WEPQQNCAATQCKHGAVYDTCGPGCIKTCDNWNEIGP 654
Query: 3960 CPDGCAEGCQCDSGFLYNGQACVPIQQC 3987
C C GC C + + + C+ C
Sbjct: 655 CNKPCVAGCHCPANLVLHKGRCIKPVLC 682
Score = 56.6 bits (135), Expect = 6e-07
Identities = 60/268 (22%), Positives = 96/268 (35%), Gaps = 25/268 (9%)
Query: 5121 CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNG 5180
C +C R C G GC C + +P +D G
Sbjct: 259 CTCRDSTVVCKRKCSHPGGCDQGQEGCCEECL--------------LRVPPEDIKVCKFG 304
Query: 5181 RYLPVNSSLLTSDCSERCSC----SSSSGLTC-QAAGCPPGRVCEVKAEARNCWATRGLC 5235
+ + + +S C+C + C + CP G++ K C G+C
Sbjct: 305 NKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTEKPGVC 364
Query: 5236 VLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVH 5295
+ + TFDG Y L+ C + P+ +V V
Sbjct: 365 TVFGDPHYNTFDGRTFNFQGTCQYVLTKDCSSPAS--PFQVLVKNDARRTRSFSWTKSVE 422
Query: 5296 IFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLL-VRQKAGVQVWLGANG 5354
+ + V+L + V NG R+ LP + DG LL V KAG+++ +
Sbjct: 423 LVLGESRVSLQQHLTVRWNGSRIALPCR---APHFHIDLDGYLLKVTTKAGLEISWDGDS 479
Query: 5355 KVAVIVSNDHAGKLCGACGNFDGDQTND 5382
V V+ + GKLCG CGN++G + +D
Sbjct: 480 FVEVMAAPHLKGKLCGLCGNYNGHKRDD 507
Score = 34.7 bits (78), Expect = 2.6
Identities = 35/140 (25%), Positives = 47/140 (33%), Gaps = 33/140 (23%)
Query: 757 ACPTSCNGAAAPSN--------------CSGRPCVEGCVCLPGF---------VASGGAC 793
AC C G N C R C EG V G + G C
Sbjct: 100 ACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTESGVRCVVHCKNPLEHLGMC 159
Query: 794 VPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQ--------VTCRDKQS-CPAG 844
P GC F+G+Q G+E + +C+C G Q ++C S P G
Sbjct: 160 CPTCP-GCVFEGVQYQEGEEFQPEGSKCTKCSCTGGRTQCVREVCPILSCPQHLSHIPPG 218
Query: 845 ERCSVQNGLLGCYPDRFGTC 864
+ C G + FG+C
Sbjct: 219 QCCPKCLGQRKVFDLPFGSC 238
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 171 bits (434), Expect = 1e-41
Identities = 155/624 (24%), Positives = 252/624 (40%), Gaps = 85/624 (13%)
Query: 1016 LRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSK-NECGILADPKGP 1074
+ GG + N Q+ + PGDCP + + +CG +A
Sbjct: 628 IESGGDFNIEIKRNNDRQDINEHIANSKIPGDCPNAVGKSYEVCEDGIQKCGKVAALSND 687
Query: 1075 FRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAG-ATVHPWRSEE--L 1131
++ C+ + C ++ CD + + C + G T WRS+ +
Sbjct: 688 YKMI------------CIDEYCQTRDKTST-CDTYSELSRLCASDGPGTFESWRSDSDVV 734
Query: 1132 CPLS-CPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALS--GES--CLPL 1186
C CP Y+ C P +C + V SEC GC C EG+ L GE C+
Sbjct: 735 CETQRCPEQHIYKECGPSNPATCSN--VAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLK 792
Query: 1187 ASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVA 1246
A C C GT + PG+ GP C S C CQ+ SC + C C+ G SL
Sbjct: 793 AECPCESSGTVYQPGEV-REGP-CGSQCTCQDAKW-SCTEALCPGR--CKVEGSSL---- 843
Query: 1247 VGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVS 1306
TTFDG +++F G C ++ +++ E +G+
Sbjct: 844 --------------TTFDGVKYNFPGNCHFLAVHN-------EDWSISVELRPCPSGQTG 882
Query: 1307 VTRVITVQVANFTLRLEQRQWKV--TVNGVDMKLPVVLANGQIRASQHGSDVV-IETDFG 1363
+ N ++ +++ + TV ++ + +I+ S + +ET F
Sbjct: 883 TCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFH 942
Query: 1364 LRVAYDLVYYVR--VTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEE 1421
+++ +V ++ V++P N + GLCG+YN +DDF + F NSWE
Sbjct: 943 VKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM 1002
Query: 1422 VVPDSPCLPPTPCPPGS-EDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDP 1480
+ CP G+ CI +EK+ E CG+L +GPL+SCH +V+P
Sbjct: 1003 M----------SCPKGNPSSCI-------SIEKEKFAERHCGILLDSSGPLASCHPIVNP 1045
Query: 1481 QGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYEL 1540
+ ++C C + LC+ + YV AC ++ WRT C CP ++
Sbjct: 1046 KPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKY 1104
Query: 1541 CADTCSLGCSALSAPPQ---CQDGCAEGCQCDSGFLYNGQA-CVPIQQCGCYHNGVYYEP 1596
C+ C +LS + +D +GC C N + CV QC CY N +P
Sbjct: 1105 NVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQP 1164
Query: 1597 EQTVLIDNCRQQCTCHAGKGMVCQ 1620
+ + D+ +C C G ++CQ
Sbjct: 1165 GKLIHTDD--NKCVCRDGI-LLCQ 1185
Score = 158 bits (400), Expect = 1e-37
Identities = 143/592 (24%), Positives = 237/592 (40%), Gaps = 84/592 (14%)
Query: 3449 CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLC 3508
CP+ + G CG ++A Y C+ + CQ + C
Sbjct: 660 CPNAVGKSYEVCEDGIQKCGKVAALSN------------DYKMICIDEYCQTRDKTS-TC 706
Query: 3509 PAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCGDSCPGSCPSLSAPEGC 3564
+ C + G E R D C Q CP Y+ CG S P +C +++ +
Sbjct: 707 DTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQ-- 764
Query: 3565 ESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCRE 3620
+S C GC C G++L CV +C C Y G+ GP C S C C++
Sbjct: 765 DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV-REGP-CGSQCTCQD 822
Query: 3621 GGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVL 3680
+ SC + C C+ G SL TTFDG +++F G C ++
Sbjct: 823 A-KWSCTEALCPGR--CKVEGSSL------------------TTFDGVKYNFPGNCHFLA 861
Query: 3681 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV--TVNGVDM 3738
+++ E +G+ + N ++ +++ + TV +
Sbjct: 862 VHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKI 914
Query: 3739 KLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VTVPGNYYQLMCGLCGNY 3795
+ + +I+ S + +ET F +++ +V ++ V++P N + GLCG+Y
Sbjct: 915 RNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSY 974
Query: 3796 NGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS-AGCIPSDKCPPELE 3854
N +DDF + F NSWE + +CP G+ + CI +E
Sbjct: 975 NNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKGNPSSCI-------SIE 1017
Query: 3855 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 3914
K+ E CG+L +GPL+SCH +V+P+ ++C C + LC+ + YV AC
Sbjct: 1018 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 1077
Query: 3915 QAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALS---APLQCPDGCAEGCQCD 3971
++ WR C CP ++ C+ C +LS D +GC C
Sbjct: 1078 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 1136
Query: 3972 SGFLYNGQA-CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQ 4022
N + CV QC CY N +P + + D+ +C C G +++CQ
Sbjct: 1137 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDD--NKCVCRDG-ILLCQ 1185
Score = 157 bits (397), Expect = 3e-37
Identities = 143/592 (24%), Positives = 235/592 (39%), Gaps = 84/592 (14%)
Query: 2248 CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLC 2307
CP+ + G CG ++A Y C+ + CQ + C
Sbjct: 660 CPNAVGKSYEVCEDGIQKCGKVAALSN------------DYKMICIDEYCQTRDKTS-TC 706
Query: 2308 PAVATYVAACQAAGAQLREWRRPD---FCPFQ-CPAHSHYELCGDSCPGSCPSLSAPEGC 2363
+ C + G E R D C Q CP Y+ CG S P +C +++ +
Sbjct: 707 DTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQ-- 764
Query: 2364 ESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCRE 2419
+S C GC C G++L CV +C C Y G+ GP C S C C++
Sbjct: 765 DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV-REGP-CGSQCTCQD 822
Query: 2420 GGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVL 2479
+ SC + C C+ G SL TTFDG +++F G C ++
Sbjct: 823 A-KWSCTEALCPGR--CKVEGSSL------------------TTFDGVKYNFPGNCHFLA 861
Query: 2480 AQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKV--TVNGVDM 2537
+++ E +G+ + N ++ +++ + TV +
Sbjct: 862 VHN-------EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKI 914
Query: 2538 KLPVVLANGQIRASQHGSDVV-IETDFGLRVAYDLVYYVR--VTVPGNYYQLMCGLCGNY 2594
+ + +I+ S + +ET F +++ +V ++ V++P N + GLCG+Y
Sbjct: 915 RNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSY 974
Query: 2595 NGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGS-EGCIPSEECPPELE 2653
N +DDF + F NSWE + +CP G+ CI +E
Sbjct: 975 NNKAEDDFMSSQNILEKTSQAFANSWEMM----------SCPKGNPSSCI-------SIE 1017
Query: 2654 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713
K+ E CG+L +GPL+SCH +V+P+ ++C C + LC+ + YV AC
Sbjct: 1018 KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKAC 1077
Query: 2714 QAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALS---APLQCPDGCAEGCQCD 2770
+ WR C CP ++ C+ C +LS D +GC C
Sbjct: 1078 AEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCP 1136
Query: 2771 SGFLYNGQA-CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQ 2821
N + CV QC CY N +P + + D+ +C C G +++CQ
Sbjct: 1137 DAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDD--NKCVCRDG-ILLCQ 1185
Score = 141 bits (355), Expect = 2e-32
Identities = 142/549 (25%), Positives = 213/549 (38%), Gaps = 93/549 (16%)
Query: 3106 CVLDVCMGGGDRDILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCG 3161
C+ + C D+ C + C + G E WR+ V CE CPE Y+ CG
Sbjct: 692 CIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 750
Query: 3162 PPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYH 3217
P PA+C + AP + CV GC C G++L +CV L C C ++GT +
Sbjct: 751 PSNPATCSNVAPFQ-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVY 804
Query: 3218 EAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWG 3277
+ G +G C C C S CT A C C+ G
Sbjct: 805 QPGEV--REGPCGSQCTCQDAKWS--CTEALC--------------------PGRCKVEG 840
Query: 3278 DPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL- 3335
T DG +++F G C +L + E+++++V S Q + SVTL
Sbjct: 841 SS-LTTFDGVKYNFPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLL 891
Query: 3336 ---------QIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGL 3386
++N T++ K++ G + + Q+ + ++L V T +
Sbjct: 892 LNSSVPVDKYVFNSDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHV 943
Query: 3387 SLAFDGDSFVRLRV--PAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVG 3436
L ++L V P GLCG+YN DD K W++
Sbjct: 944 KLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM- 1002
Query: 3437 GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 3496
C K PS C ++E F CG++ + GPLA CH +V P Y + C
Sbjct: 1003 --MSC----PKGNPSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKY 1055
Query: 3497 ACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCP 3556
C + LC + YV AC + W R C CP+ ++ +C SC
Sbjct: 1056 TCTCENSQDCLCTILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCR 1114
Query: 3557 SLSAPE---GCESACREGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 3612
SLS + E +GC C DA + + CV QC C +D G+ +
Sbjct: 1115 SLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTD--- 1171
Query: 3613 DSLCRCREG 3621
D+ C CR+G
Sbjct: 1172 DNKCVCRDG 1180
Score = 140 bits (352), Expect = 4e-32
Identities = 142/549 (25%), Positives = 212/549 (38%), Gaps = 93/549 (16%)
Query: 1905 CVLDVCMGGGDRDILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCG 1960
C+ + C D+ C + C + G E WR+ V CE CPE Y+ CG
Sbjct: 692 CIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 750
Query: 1961 SPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYH 2016
PA+C + AP + CV GC C G++L +CV L C C ++GT +
Sbjct: 751 PSNPATCSNVAPFQ-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVY 804
Query: 2017 EAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWG 2076
+ G +G C C C S CT A C C+ G
Sbjct: 805 QPGEV--REGPCGSQCTCQDAKWS--CTEALC--------------------PGRCKVEG 840
Query: 2077 DPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL- 2134
T DG ++NF G C +L + E+++++V S Q + SVTL
Sbjct: 841 SS-LTTFDGVKYNFPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLL 891
Query: 2135 ---------QIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGL 2185
++N T++ K++ G + + Q+ + ++L V T +
Sbjct: 892 LNSSVPVDKYVFNSDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHV 943
Query: 2186 SLAFDGDSFVRLRV--PAAYAGSLCGLCGNYNQDPADDL--------KAVGGKPAGWQVG 2235
L ++L V P GLCG+YN DD K W++
Sbjct: 944 KLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM- 1002
Query: 2236 GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 2295
C K PS C ++E F CG++ + GPLA CH +V P Y + C
Sbjct: 1003 --MSC----PKGNPSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKY 1055
Query: 2296 ACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCP 2355
C + LC + YV AC + W R C CP+ ++ +C SC
Sbjct: 1056 TCTCENSQDCLCTILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCR 1114
Query: 2356 SLSAPE---GCESACREGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGC 2411
SLS + E +GC C DA + + CV QC C +D G+ +
Sbjct: 1115 SLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTD--- 1171
Query: 2412 DSLCRCREG 2420
D+ C CR+G
Sbjct: 1172 DNKCVCRDG 1180
Score = 135 bits (339), Expect = 1e-30
Identities = 143/552 (25%), Positives = 211/552 (38%), Gaps = 99/552 (17%)
Query: 4307 CVLDVCMGGGDRDILCKALASYVAACQAAGV-VIEDWRAQ--VGCEIT-CPENSHYEVCG 4362
C+ + C D+ C + C + G E WR+ V CE CPE Y+ CG
Sbjct: 692 CIDEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECG 750
Query: 4363 PPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS----ADRCVPLNNGCGCWANGTYH 4418
P PA+C + AP + CV GC C G++L +CV L C C ++GT +
Sbjct: 751 PSNPATCSNVAPFQ-----DSECVSGCTCPEGYLLDDIGEKGKCV-LKAECPCESSGTVY 804
Query: 4419 EAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWG 4478
+ G +G C C C S CT A C C+ G
Sbjct: 805 QPGEV--REGPCGSQCTCQDAKWS--CTEALC--------------------PGRCKVEG 840
Query: 4479 DPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGS-QAVSYTRSVTL- 4536
T DG +++F G C +L + E+++++V S Q + SVTL
Sbjct: 841 SS-LTTFDGVKYNFPGNCHFLA--------VHNEDWSISVELRPCPSGQTGTCLNSVTLL 891
Query: 4537 ---------QIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGL 4587
++N T++ K++ G + + Q+ + ++L V T +
Sbjct: 892 LNSSVPVDKYVFNSDGTVTND---KIRNQGYYYSDKIQIFNASSSYLQ-----VETYFHV 943
Query: 4588 SLAFDGDSFVRLRV--PAAYAASLCGLCGNYNQDPADDL--------KAVGGKPAGWQVG 4637
L ++L V P GLCG+YN DD K W++
Sbjct: 944 KLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEM- 1002
Query: 4638 GAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD 4697
C K PS C ++E F CG++ + GPLA CH +V P Y + C
Sbjct: 1003 --MSC----PKGNPSSCISIEKEKFAERH-CGILLDSSGPLASCHPIVNPKPYHEECKKY 1055
Query: 4698 ACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCP 4757
C + LC + YV AC + W R C CP+ ++ +C SC
Sbjct: 1056 TCTCENSQDCLCTILGNYVKACAEKETYIVGW-RTGLCEHSCPSGLVFKYNVKACNSSCR 1114
Query: 4758 SLSAPE---GCESACREGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGP-- 4811
SLS + E +GC C DA + + CV QC C Y EV PG
Sbjct: 1115 SLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDC------YINDEVMQPGKLI 1168
Query: 4812 -ECERRCECGPG 4822
+ +C C G
Sbjct: 1169 HTDDNKCVCRDG 1180
Score = 130 bits (327), Expect = 4e-29
Identities = 134/596 (22%), Positives = 225/596 (37%), Gaps = 74/596 (12%)
Query: 643 DDGDYLCEDGCQNNCPACTPGQAQHYE-GDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCV 701
D +++ +CP + E G + CG + L + + C+
Sbjct: 646 DINEHIANSKIPGDCPNAVGKSYEVCEDGIQKCGKVAALSNDYKMI------------CI 693
Query: 702 YDLCVVGGERLSLCRGLSAYAQACLELGISVGD-WRSPANCPLS---CPANSRYELCGPA 757
+ C ++ S C S ++ C G + WRS ++ CP Y+ CGP+
Sbjct: 694 DEYCQTR-DKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPS 752
Query: 758 CPTSCNGAAAPSNCSGRPCVEGCVCLPGF----VASGGACVPASSCGCTFQGLQLAPGQE 813
P +C+ A + CV GC C G+ + G CV + C C G PG+
Sbjct: 753 NPATCSNVAPFQDSE---CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV 809
Query: 814 VWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYV 873
+ C +CTC A T + CP RC V+ L
Sbjct: 810 --REGPCGSQCTCQDAKWSCT---EALCPG--RCKVEGSSL------------------T 844
Query: 874 SFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVA 933
+FDG +++F G C +L V + ++ ++ + G+ S T + K
Sbjct: 845 TFDGVKYNFPGNCHFLAVHN--EDWSISVELRPCPSGQTGTCLNSVTLLLNSSVPVDKYV 902
Query: 934 VRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAV-VRTDFG--LTVTYDWNARVTAK 990
+ + +D ++ + +D ++Q+F + V T F L + ++
Sbjct: 903 FNSD---GTVTNDKIRNQGYYYSD-KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVS 958
Query: 991 VPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPK 1050
+P + GLCG++N DD + AF NSW+ + C P C
Sbjct: 959 MPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMS---CPKGNPSSCIS 1015
Query: 1051 LDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALA 1110
++ ++ ++ CGIL D GP CH ++P+ +C C LC L
Sbjct: 1016 IE----KEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILG 1071
Query: 1111 TYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPV-PGGCGSE--CH 1167
Y AC + WR+ LC SCP ++ C SC L C E
Sbjct: 1072 NYVKACAEKETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPV 1130
Query: 1168 EGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLV 1222
+GC C + + E +C+ + C C PG+ + D+ C C++G L+
Sbjct: 1131 DGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTD---DNKCVCRDGILL 1183
Score = 130 bits (327), Expect = 4e-29
Identities = 139/589 (23%), Positives = 205/589 (34%), Gaps = 92/589 (15%)
Query: 4650 CPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLC 4709
CP+ + G CG ++A Y C+ + CQ + C
Sbjct: 660 CPNAVGKSYEVCEDGIQKCGKVAALSN------------DYKMICIDEYCQTRDKTS-TC 706
Query: 4710 PAVATYVAACQAAGAQLGEWRRPD---FCPLQ-CPAHSHYELCGDSCPVSCPSLSAPEGC 4765
+ C + G E R D C Q CP Y+ CG S P +C +++ +
Sbjct: 707 DTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQ-- 764
Query: 4766 ESACREGCVCDAGFVLSG----DTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGP 4821
+S C GC C G++L CV +C C G Y GEV R CG
Sbjct: 765 DSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEV--------REGPCG- 815
Query: 4822 GGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGSCSY 4880
+C +D +C C GRC G T DG Y+ G+C +
Sbjct: 816 ---------------SQCTCQDAKWSCTEALCPGRCKVEGS-SLTTFDGVKYNFPGNCHF 859
Query: 4881 VLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAV 4940
+ +ED+SI +E Q V+L V VD V
Sbjct: 860 LAVH-------NEDWSISVELRPCPSGQ---TGTCLNSVTLLLNSSVPVDKYVFNSDGTV 909
Query: 4941 GRVRVTAEG------------RNMVLQTTK----GLRLLFDGDAHLLMSIPSPFRGRLCG 4984
++ +G + LQ L++ L +S+P G
Sbjct: 910 TNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVG 969
Query: 4985 LCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPY 5044
LCG++N DDF+ + + F +W KG P C E+ A
Sbjct: 970 LCGSYNNKAEDDFMSSQNILEKTSQAFANSWEMMSCPKG-----NPSSCISIEKEKFA-- 1022
Query: 5045 ESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAA 5104
CG L + GP A+C +++P Y +C C + + LC L Y AC
Sbjct: 1023 --ERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEK 1080
Query: 5105 GVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGL-TGCTTR--CFEGCECDD-R 5160
+ WRT C CP+ + + C SC +LS C +GC C D
Sbjct: 1081 ETYIVGWRT-GLCEHSCPSGLVFKYNVKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAM 1139
Query: 5161 FLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQ 5209
+ ++G C+ C C N + + T D +C C L CQ
Sbjct: 1140 YQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDD--NKCVCRDGI-LLCQ 1185
Score = 120 bits (301), Expect = 4e-26
Identities = 149/624 (23%), Positives = 228/624 (36%), Gaps = 117/624 (18%)
Query: 3844 IPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSIL 3903
IP D CP + K Y+ E LS+ +K++ CI + C S
Sbjct: 656 IPGD-CPNAVGKSYEVCEDGIQKCGKVAALSNDYKMI--------CIDEYCQTRDKTST- 705
Query: 3904 CSNIHAYVSACQAAG-GHVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALSAPLQ 3959
C C + G G E WR+++ E CP+ Y+ C + CS + AP Q
Sbjct: 706 CDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNV-APFQ 764
Query: 3960 CPDGCAEGCQCDSGFLYNGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHV 4015
+ C GC C G+L + CV +C C +G Y+P + V C QCTC
Sbjct: 765 DSE-CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQD 822
Query: 4016 GKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATC 4075
K C E C PG+ CK +G
Sbjct: 823 AKWS-CTEALC-PGR---------------------------CKVEGSS----------- 842
Query: 4076 WLWGDPHYHSFDGRKFDFQGTCNYV----------LATTGCPGVSTQGLTPFTVTTKNQN 4125
+FDG K++F G C+++ + CP S Q T T N
Sbjct: 843 -------LTTFDGVKYNFPGNCHFLAVHNEDWSISVELRPCP--SGQTGTCLNSVTLLLN 893
Query: 4126 RGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALL 4185
P YV ++ ++ D K+R G + +I + +S L
Sbjct: 894 SSVPVDKYV-------FNSDGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQ 936
Query: 4186 VADF---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIW 4242
V + LQ+ ++ V++P + GLCG+ + +D + L + +
Sbjct: 937 VETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAF 996
Query: 4243 GGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPES 4302
SW C SC + +++ + CG L +G P +CH V P+
Sbjct: 997 ANSWEMMS----CPKGNPSSCISIEKEKFAERH----CGILLDSSG-PLASCHPIVNPKP 1047
Query: 4303 FFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCG 4362
+ + C C +D LC L +YV AC I WR + CE +CP ++
Sbjct: 1048 YHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNV 1106
Query: 4363 PPCPASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAG 4421
C +SC S + E V+GC C DA + + CV L + C C+ N + G
Sbjct: 1107 KACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPG 1165
Query: 4422 SEFWADGTCSQWCRCGPGGGSLVC 4445
D +C G L+C
Sbjct: 1166 KLIHTDDN-----KCVCRDGILLC 1184
Score = 119 bits (299), Expect = 6e-26
Identities = 146/620 (23%), Positives = 226/620 (36%), Gaps = 116/620 (18%)
Query: 2647 ECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNI 2706
+CP + K Y+ E LS+ +K++ CI + C S C
Sbjct: 659 DCPNAVGKSYEVCEDGIQKCGKVAALSNDYKMI--------CIDEYCQTRDKTST-CDTY 709
Query: 2707 HAYVSACQAAG-GQVEPWRNETFCPME---CPQNSHYELCADTCSLGCSALSAPLQCPDG 2762
C + G G E WR+++ E CP+ Y+ C + CS + AP Q +
Sbjct: 710 SELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNV-APFQDSE- 767
Query: 2763 CAEGCQCDSGFLYNGQA----CVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVV 2818
C GC C G+L + CV +C C +G Y+P + V C QCTC K
Sbjct: 768 CVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS 826
Query: 2819 VCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWG 2878
C E C PG+ CK +G
Sbjct: 827 -CTEALC-PGR---------------------------CKVEGSS--------------- 842
Query: 2879 DPHYHSFDGRKFDFQGTCNYV----------LATTGCPGVSTQGLTPFTVTTKNQNRGNP 2928
+FDG K++F G C+++ + CP S Q T T N P
Sbjct: 843 ---LTTFDGVKYNFPGNCHFLAVHNEDWSISVELRPCP--SGQTGTCLNSVTLLLNSSVP 897
Query: 2929 AVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF 2988
YV ++ ++ D K+R G + +I + +S L V +
Sbjct: 898 VDKYV-------FNSDGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQVETY 940
Query: 2989 ---GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSW 3045
LQ+ ++ V++P + GLCG+ + +D + L + + SW
Sbjct: 941 FHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSW 1000
Query: 3046 RAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKG 3105
C SC + +++ + CG L +G P +CH V P+ + +
Sbjct: 1001 EMMS----CPKGNPSSCISIEKEKFAERH----CGILLDSSG-PLASCHPIVNPKPYHEE 1051
Query: 3106 CVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCP 3165
C C +D LC L +YV AC I WR + CE +CP ++ C
Sbjct: 1052 CKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACN 1110
Query: 3166 ASCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFW 3224
+SC S + E V+GC C DA + + CV L + C C+ N + G
Sbjct: 1111 SSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIH 1169
Query: 3225 ADGTCSQWCRCGPGGGSLVC 3244
D +C G L+C
Sbjct: 1170 TDDN-----KCVCRDGILLC 1184
Score = 117 bits (294), Expect = 2e-25
Identities = 144/619 (23%), Positives = 222/619 (35%), Gaps = 116/619 (18%)
Query: 1447 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 1506
CP + K Y+ E LS+ +K++ CI + C S C
Sbjct: 660 CPNAVGKSYEVCEDGIQKCGKVAALSNDYKMI--------CIDEYCQTRDKTST-CDTYS 710
Query: 1507 AYVSACQAAG-GHVEPWRTETFCPME---CPPNSHYELCADTCSLGCSALSAPPQCQDGC 1562
C + G G E WR+++ E CP Y+ C + CS ++ P C
Sbjct: 711 ELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVA--PFQDSEC 768
Query: 1563 AEGCQCDSGFLYNGQA----CVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMV 1618
GC C G+L + CV +C C +G Y+P + V C QCTC K
Sbjct: 769 VSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGE-VREGPCGSQCTCQDAKWS- 826
Query: 1619 CQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGD 1678
C E C PG+ CK +G
Sbjct: 827 CTEALC-PGR---------------------------CKVEGSS---------------- 842
Query: 1679 PHYHSFDGRKFDFQGTCNYV----------LATTGCPGVSTQGLTPFTVTTKNQNRGNPA 1728
+FDG K++F G C+++ + CP S Q T T N P
Sbjct: 843 --LTTFDGVKYNFPGNCHFLAVHNEDWSISVELRPCP--SGQTGTCLNSVTLLLNSSVPV 898
Query: 1729 VSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADF- 1787
YV ++ ++ D K+R G + +I + +S L V +
Sbjct: 899 DKYV-------FNSDGTVTND---KIRNQGYYYS-------DKIQIFNASSSYLQVETYF 941
Query: 1788 --GLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWR 1845
LQ+ ++ V++P + GLCG+ + +D + L + + SW
Sbjct: 942 HVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSWE 1001
Query: 1846 APGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGC 1905
C SC + +++ + CG L +G P +CH V P+ + + C
Sbjct: 1002 MMS----CPKGNPSSCISIEKEKFAERH----CGILLDSSG-PLASCHPIVNPKPYHEEC 1052
Query: 1906 VLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPA 1965
C +D LC L +YV AC I WR + CE +CP ++ C +
Sbjct: 1053 KKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL-CEHSCPSGLVFKYNVKACNS 1111
Query: 1966 SCPSPAPLTTPAVCEGPCVEGCQC-DAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWA 2024
SC S + E V+GC C DA + + CV L + C C+ N + G
Sbjct: 1112 SCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCV-LKSQCDCYINDEVMQPGKLIHT 1170
Query: 2025 DGTCSQWCRCGPGGGSLVC 2043
D +C G L+C
Sbjct: 1171 DDN-----KCVCRDGILLC 1184
Score = 115 bits (287), Expect = 2e-24
Identities = 112/431 (25%), Positives = 170/431 (39%), Gaps = 55/431 (12%)
Query: 452 GQRCQVVGGKAGCV-AESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPA 510
G +C K C A C+ +G TTFDG +Y+ G C + V +ED ++
Sbjct: 815 GSQCTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVH--NEDWSISV 871
Query: 511 FSVEAKNEHRGSRRVSYVGL----VTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566
+ G+ S L V V Y + T V N + R
Sbjct: 872 ELRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGT--------VTNDKIRNQGYYYSD 923
Query: 567 RLRVYQSGPRAV-VELVFG--LVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623
+++++ + + VE F L + QL +S+P GLCG+YN DDF+
Sbjct: 924 KIQIFNASSSYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFM 983
Query: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683
+ L + FA+SW++ C G N +C + + + +R CG+L GP
Sbjct: 984 SSQNILEKTSQAFANSWEMMS----CPKG---NPSSCISIEKEKF-AERHCGILLDSSGP 1035
Query: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL 743
A CH ++P+P+ E+C C + LC L Y +AC E + WR+ C
Sbjct: 1036 LASCHPIVNPKPYHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCEH 1094
Query: 744 SCPANSRYELCGPACPTSCNGAAAPSNCSGRPC------VEGCVCLPGFVASG-GACVPA 796
SCP+ ++ AC +SC + R C V+GC C + G CV
Sbjct: 1095 SCPSGLVFKYNVKACNSSCRSLSE----RDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLK 1150
Query: 797 SSCGCTFQGLQLAPGQEVWADE----------LCQ-----RRCTCNGATHQVTCRD-KQS 840
S C C + PG+ + D+ LCQ C+G V C D K
Sbjct: 1151 SQCDCYINDEVMQPGKLIHTDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQ 1210
Query: 841 CPAGERCSVQN 851
CS +N
Sbjct: 1211 RRTNRTCSTRN 1221
Score = 110 bits (276), Expect = 3e-23
Identities = 83/252 (32%), Positives = 112/252 (44%), Gaps = 24/252 (9%)
Query: 990 KVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCP 1049
K+ ++ +CGLCGN NGD DD R A+ AL FGNSW +T C T P
Sbjct: 1255 KIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSW--KTSQECSDTVAQTFP 1312
Query: 1050 KLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCL--LPGQSGPLCD 1107
DS + + +C IL D FR+CH+K+DP C+ + C + G+ C
Sbjct: 1313 -CDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1369
Query: 1108 ALATYAAACQAAGATVHPWRSEELCPLSCPPHS-------HYEACSYGCPLSCGDLPVPG 1160
A+A YA AC A G V WR LCP+ C ++ HYE C +C D V G
Sbjct: 1370 AVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV-G 1427
Query: 1161 GCGSECHEGCV--CDEGFALSGES---CLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCH 1215
S EGC C + E+ C+ L+ C C + P G C C+
Sbjct: 1428 QKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI-PAGGVI--EDNCGRTCY 1484
Query: 1216 CQEGGLVSCESS 1227
C G L E++
Sbjct: 1485 CIAGQLECSETA 1496
Score = 108 bits (271), Expect = 1e-22
Identities = 76/238 (31%), Positives = 103/238 (43%), Gaps = 26/238 (10%)
Query: 603 FQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTP 662
FQ +VCGLCGN NGD DDF T ++A A+EF +SWK C D P C
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQE---CSDTVAQTFP-CDS 1315
Query: 663 GQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCV--VGGERLSLCRGLSA 720
R C +L D F CH+ +DP + + C+ + C + G+ L C ++
Sbjct: 1316 NPYCKAWAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAVAM 1373
Query: 721 YAQACLELGISVGDWRSPANCPLSC-----PANSR--YELCGPACPTSCNGAAAPSNCSG 773
YA+AC +G+ V WR P CP+ C P R YE CG +C S
Sbjct: 1374 YAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKFSS 1432
Query: 774 RPCVEGCVC-----LPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTC 826
+EGC P + CV S C C + + A G ++ C R C C
Sbjct: 1433 --LLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGV---IEDNCGRTCYC 1485
Score = 103 bits (258), Expect = 4e-21
Identities = 86/315 (27%), Positives = 126/315 (40%), Gaps = 55/315 (17%)
Query: 4978 FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCL 5037
F+G++CGLCGN NG+ DDF S AS FG +W+ +S+ C +
Sbjct: 1260 FQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---TSQECSD----------T 1306
Query: 5038 AEETAPYESN--------EACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDK 5087
+T P +SN C LR+ F C + PS Y C+ + CA +G
Sbjct: 1307 VAQTFPCDSNPYCKAWAVRKCEILRD--STFRDCHNKVDPSAYHDVCIEEACACDMEGKY 1364
Query: 5088 AFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS-------HYSIC----TRTCQG 5136
C ++A Y AC A GV V WR + CP++C ++ HY C +TC+
Sbjct: 1365 LGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKD 1423
Query: 5137 SCAA---LSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSD 5193
S L GC +C + D + C+ + +C C +N +P ++ +
Sbjct: 1424 QLVGQKFSSLLEGCYAKCPDSAPYLDENTMK---CVSLSECSCFYND-VIPA-GGVIEDN 1478
Query: 5194 CSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGAT 5253
C C C + L C P V T +LS GA +T G
Sbjct: 1479 CGRTCYCIAGQ-LECSET-APTNSTFAVS-------TTTATTILSTGAAITLVTGGPSTA 1529
Query: 5254 TS-PGVYELSSRCPG 5267
S P + SS G
Sbjct: 1530 ASIPAITTSSSETTG 1544
Score = 102 bits (254), Expect = 1e-20
Identities = 81/251 (32%), Positives = 105/251 (41%), Gaps = 33/251 (13%)
Query: 1385 QMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPT-PCPPGSEDCIP 1443
++CGLCGN NGD KDDF S A A EFGNSW+ S + T PC D P
Sbjct: 1263 KVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPC-----DSNP 1317
Query: 1444 SHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSIL 1501
C +K C +L T CH VDP CI + C G
Sbjct: 1318 --YCKAWAVRK------CEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGF 1367
Query: 1502 CSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNS-------HYELCADTCSLGCSALSA 1554
C+ + Y AC A G V WR CP+ C + HYE C + C
Sbjct: 1368 CTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLV 1426
Query: 1555 PPQCQ---DGCAEGCQCDSGFL-YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCT 1610
+ +GC C + +L N CV + +C C++N V P V+ DNC + C
Sbjct: 1427 GQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIEDNCGRTCY 1484
Query: 1611 CHAGKGMVCQE 1621
C AG+ + C E
Sbjct: 1485 CIAGQ-LECSE 1494
Score = 101 bits (252), Expect = 2e-20
Identities = 81/247 (32%), Positives = 102/247 (41%), Gaps = 36/247 (14%)
Query: 3788 MCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSD 3847
+CGLCGN NGD KDDF S A A EFGNSW+ C A P D
Sbjct: 1264 VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK---------TSQECSDTVAQTFPCD 1314
Query: 3848 KCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--GNLSILCS 3905
P +K C +L T CH VDP CI + C G C+
Sbjct: 1315 SNPYCKAWAVRK---CEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1369
Query: 3906 NIHAYVSACQAAGGHVEPWRNETFCPMECPQNS-------HYELC----ADTC--SLGCS 3952
+ Y AC A G V WR CP+ C + HYE C A TC L
Sbjct: 1370 AVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQ 1428
Query: 3953 ALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQC 4011
S+ L +GC C + +L N CV + +C C++N V P V+ DNC + C
Sbjct: 1429 KFSSLL---EGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIEDNCGRTC 1483
Query: 4012 TCHVGKV 4018
C G++
Sbjct: 1484 YCIAGQL 1490
Score = 99.0 bits (245), Expect = 1e-19
Identities = 80/254 (31%), Positives = 100/254 (39%), Gaps = 50/254 (19%)
Query: 2587 MCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSW-------EEVVPDSPCLPPPTCPPGS 2639
+CGLCGN NGD KDDF S A A EFGNSW + V PC P C
Sbjct: 1264 VCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCDSNPYC---- 1319
Query: 2640 EGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGG--G 2697
K C +L T CH VDP CI + C G
Sbjct: 1320 ---------------KAWAVRKCEILRDST--FRDCHNKVDPSAYHDVCIEEACACDMEG 1362
Query: 2698 NLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNS-------HYELC----ADTC 2746
C+ + Y AC A G V WR CP+ C + HYE C A TC
Sbjct: 1363 KYLGFCTAVAMYAEACSAVGVCVS-WRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTC 1421
Query: 2747 --SLGCSALSAPLQCPDGCAEGCQCDSGFL-YNGQACVPIQQCGCYHNGAYYEPEQTVLI 2803
L S+ L +GC C + +L N CV + +C C++N P V+
Sbjct: 1422 KDQLVGQKFSSLL---EGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVI--PAGGVIE 1476
Query: 2804 DNCRQQCTCHVGKV 2817
DNC + C C G++
Sbjct: 1477 DNCGRTCYCIAGQL 1490
Score = 94.7 bits (234), Expect = 2e-18
Identities = 77/284 (27%), Positives = 114/284 (40%), Gaps = 46/284 (16%)
Query: 2198 RVPAAYAGSLCGLCGNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSP 2251
++ A+ G +CGLCGN N D DD A G G +Q C + V++ P
Sbjct: 1255 KIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFP 1312
Query: 2252 CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPA 2309
C C ++ D CH V P+ Y C+ + AC ++G G C A
Sbjct: 1313 CDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTA 1370
Query: 2310 VATYVAACQAAGAQLREWRRPDFCPFQCPAHS-------HYELCGDSCPGSCPS------ 2356
VA Y AC A G + WR+P+ CP C ++ HYE CG +C
Sbjct: 1371 VAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQK 1429
Query: 2357 -LSAPEGCESACREGCVCDAGFVLSGDT--CVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 2413
S EGC + C D+ L +T CV + +C C ++D P G C
Sbjct: 1430 FSSLLEGCYAKCP-----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGR 1481
Query: 2414 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASG 2457
C C G++ C ++ P+ + +TT ++G
Sbjct: 1482 TCYC-IAGQLECSETA--------PTNSTFAVSTTTATTILSTG 1516
Score = 94.7 bits (234), Expect = 2e-18
Identities = 77/284 (27%), Positives = 114/284 (40%), Gaps = 46/284 (16%)
Query: 3399 RVPAAYAGSLCGLCGNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSP 3452
++ A+ G +CGLCGN N D DD A G G +Q C + V++ P
Sbjct: 1255 KIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ--TFP 1312
Query: 3453 CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQGHPGGLCPA 3510
C C ++ D CH V P+ Y C+ + AC ++G G C A
Sbjct: 1313 CDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTA 1370
Query: 3511 VATYVAACQAAGAQLREWRRPDFCPFQCPAHS-------HYELCGDSCPGSCPS------ 3557
VA Y AC A G + WR+P+ CP C ++ HYE CG +C
Sbjct: 1371 VAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQK 1429
Query: 3558 -LSAPEGCESACREGCVCDAGFVLSGDT--CVPVGQCGCLHDDRYYPLGQTFYPGPGCDS 3614
S EGC + C D+ L +T CV + +C C ++D P G C
Sbjct: 1430 FSSLLEGCYAKCP-----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGR 1481
Query: 3615 LCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASG 3658
C C G++ C ++ P+ + +TT ++G
Sbjct: 1482 TCYC-IAGQLECSETA--------PTNSTFAVSTTTATTILSTG 1516
Score = 94.7 bits (234), Expect = 2e-18
Identities = 75/256 (29%), Positives = 106/256 (41%), Gaps = 38/256 (14%)
Query: 4600 RVPAAYAASLCGLCGNYNQDPADDLK------AVGGKPAGWQVGGAQGCGECVSKPCPSP 4653
++ A+ +CGLCGN N D DD A G G +Q C + V++ P
Sbjct: 1255 KIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQTFPCD 1314
Query: 4654 CTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDAC--QVQGHPGGLCPA 4711
P + C ++ D CH V P+ Y C+ +AC ++G G C A
Sbjct: 1315 SNPYCKA--WAVRKCEILR--DSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTA 1370
Query: 4712 VATYVAACQAAGAQLGEWRRPDFCPLQCPAHS-------HYELCGDSCPVSCPS------ 4758
VA Y AC A G + WR+P+ CP+ C ++ HYE CG +C
Sbjct: 1371 VAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQK 1429
Query: 4759 -LSAPEGCESACREGCVCDAGFVLSGDT--CVPVGQCGCLHDGRYYPLGEVFYPGPECER 4815
S EGC + C D+ L +T CV + +C C ++ P G V C R
Sbjct: 1430 FSSLLEGCYAKCP-----DSAPYLDENTMKCVSLSECSCFYND-VIPAGGVI--EDNCGR 1481
Query: 4816 RCECGPGGHVTCQEGA 4831
C C G + C E A
Sbjct: 1482 TCYC-IAGQLECSETA 1496
Score = 68.2 bits (165), Expect = 2e-10
Identities = 63/243 (25%), Positives = 96/243 (39%), Gaps = 24/243 (9%)
Query: 1806 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 1865
++ G VCGLCGN + + +D ++A +G SW+ C D + P C
Sbjct: 1259 AFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTVAQTFP-CD 1314
Query: 1866 EDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL--CKAL 1923
+ + C L T F CH V P ++ C+ + C + L C A+
Sbjct: 1315 SNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1371
Query: 1924 ASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGSPCPASCPSP-APLTT 1975
A Y AC A GV + WR C + C + HYE CG+ +C
Sbjct: 1372 AMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKF 1430
Query: 1976 PAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 2034
++ EG C C A ++ + +CV L+ C C+ N G + C + C C
Sbjct: 1431 SSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IEDNCGRTCYC 1485
Query: 2035 GPG 2037
G
Sbjct: 1486 IAG 1488
Score = 67.8 bits (164), Expect = 3e-10
Identities = 63/243 (25%), Positives = 95/243 (39%), Gaps = 24/243 (9%)
Query: 4208 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 4267
++ G VCGLCGN + + +D ++A +G SW+ C D + P C
Sbjct: 1259 AFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTVAQTFP-CD 1314
Query: 4268 EDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL--CKAL 4325
+ + C L T F CH V P ++ C+ + C + L C A+
Sbjct: 1315 SNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1371
Query: 4326 ASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSP-APLTT 4377
A Y AC A GV + WR C + C + HYE CG +C
Sbjct: 1372 AMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKF 1430
Query: 4378 PAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 4436
++ EG C C A ++ + +CV L+ C C+ N G + C + C C
Sbjct: 1431 SSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IEDNCGRTCYC 1485
Query: 4437 GPG 4439
G
Sbjct: 1486 IAG 1488
Score = 67.4 bits (163), Expect = 4e-10
Identities = 63/243 (25%), Positives = 95/243 (39%), Gaps = 24/243 (9%)
Query: 3007 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 3066
++ G VCGLCGN + + +D ++A +G SW+ C D + P C
Sbjct: 1259 AFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKT---SQECSDTVAQTFP-CD 1314
Query: 3067 EDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDIL--CKAL 3124
+ + C L T F CH V P ++ C+ + C + L C A+
Sbjct: 1315 SNPYCKAWAVRKCEILRDST---FRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCTAV 1371
Query: 3125 ASYVAACQAAGVVIEDWRAQVGCEITCPENS-------HYEVCGPPCPASCPSP-APLTT 3176
A Y AC A GV + WR C + C + HYE CG +C
Sbjct: 1372 AMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWHYEPCGTVTAKTCKDQLVGQKF 1430
Query: 3177 PAVCEGPCVEGCQCDAGFV-LSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRC 3235
++ EG C C A ++ + +CV L+ C C+ N G + C + C C
Sbjct: 1431 SSLLEG-CYAKCPDSAPYLDENTMKCVSLSE-CSCFYNDVIPAGGV---IEDNCGRTCYC 1485
Query: 3236 GPG 3238
G
Sbjct: 1486 IAG 1488
Score = 60.1 bits (144), Expect = 6e-08
Identities = 51/197 (25%), Positives = 82/197 (41%), Gaps = 33/197 (16%)
Query: 5063 CQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAV-KPWRTDS--FCPL 5119
C V + S ++ D Q DK C + + + C + G + WR+DS C
Sbjct: 678 CGKVAALSNDYKMICIDEYCQTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCET 737
Query: 5120 H-CPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDC 5174
CP Y C + +C+ ++ + C GC C + +LL +G C+ +C
Sbjct: 738 QRCPEQHIYKECGPSNPATCSNVAPFQD--SECVSGCTCPEGYLLDDIGEKGKCVLKAEC 795
Query: 5175 GCTHNGR-YLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRG 5233
C +G Y P + C +C+C + +C A C PGR C+V+
Sbjct: 796 PCESSGTVYQP--GEVREGPCGSQCTCQDAK-WSCTEALC-PGR-CKVE----------- 839
Query: 5234 LCVLSVGANLTTFDGAR 5250
G++LTTFDG +
Sbjct: 840 ------GSSLTTFDGVK 850
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 264,422,782
Number of Sequences: 37866
Number of extensions: 15171611
Number of successful extensions: 58643
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 247
Number of HSP's that attempted gapping in prelim test: 41121
Number of HSP's gapped (non-prelim): 9391
length of query: 5405
length of database: 18,247,518
effective HSP length: 125
effective length of query: 5280
effective length of database: 13,514,268
effective search space: 71355335040
effective search space used: 71355335040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 74 (33.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.