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Search of human proteins with 153946399
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153946399 BCL2/adenovirus E1B 19kD interacting protein 1
isoform BNIP1-b [Homo sapiens]
(271 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153946399 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 523 e-149
gi|153946405 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 439 e-124
gi|153946401 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 414 e-116
gi|153946403 BCL2/adenovirus E1B 19kD interacting protein 1 isof... 330 8e-91
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 42 7e-04
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 39 0.005
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 39 0.005
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 39 0.006
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 38 0.011
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 38 0.011
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 38 0.011
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 38 0.011
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 38 0.011
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 38 0.011
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 38 0.011
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 38 0.011
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 37 0.018
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 37 0.024
gi|58530840 desmoplakin isoform I [Homo sapiens] 34 0.12
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 34 0.12
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 34 0.12
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 34 0.12
gi|71061468 centromere protein E [Homo sapiens] 33 0.20
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 33 0.26
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 33 0.26
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 33 0.26
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 33 0.26
gi|50083293 coiled-coil domain containing 123 [Homo sapiens] 33 0.26
gi|4758650 kinesin family member 5C [Homo sapiens] 33 0.34
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 33 0.34
>gi|153946399 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1-b [Homo sapiens]
Length = 271
Score = 523 bits (1348), Expect = e-149
Identities = 271/271 (100%), Positives = 271/271 (100%)
Query: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 60
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP
Sbjct: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 60
Query: 61 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 120
VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL
Sbjct: 61 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 120
Query: 121 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 180
LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST
Sbjct: 121 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 180
Query: 181 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 240
ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR
Sbjct: 181 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 240
Query: 241 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 271
ELTDKLLIFLALALFLATVLYIVKKRLFPFL
Sbjct: 241 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 271
>gi|153946405 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1-c [Homo sapiens]
Length = 237
Score = 439 bits (1130), Expect = e-124
Identities = 237/271 (87%), Positives = 237/271 (87%), Gaps = 34/271 (12%)
Query: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 60
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP
Sbjct: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 60
Query: 61 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 120
VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL
Sbjct: 61 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 120
Query: 121 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 180
LQEVENHKKQML RKTTKESLAQTSST
Sbjct: 121 LQEVENHKKQML----------------------------------RKTTKESLAQTSST 146
Query: 181 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 240
ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR
Sbjct: 147 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 206
Query: 241 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 271
ELTDKLLIFLALALFLATVLYIVKKRLFPFL
Sbjct: 207 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 237
>gi|153946401 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1 [Homo sapiens]
Length = 228
Score = 414 bits (1064), Expect = e-116
Identities = 228/271 (84%), Positives = 228/271 (84%), Gaps = 43/271 (15%)
Query: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 60
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ
Sbjct: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ- 59
Query: 61 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 120
DLEQLAKEQDKESEKQLL
Sbjct: 60 ------------------------------------------DLEQLAKEQDKESEKQLL 77
Query: 121 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 180
LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST
Sbjct: 78 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 137
Query: 181 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 240
ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR
Sbjct: 138 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 197
Query: 241 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 271
ELTDKLLIFLALALFLATVLYIVKKRLFPFL
Sbjct: 198 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 228
>gi|153946403 BCL2/adenovirus E1B 19kD interacting protein 1 isoform
BNIP1-a [Homo sapiens]
Length = 194
Score = 330 bits (846), Expect = 8e-91
Identities = 194/271 (71%), Positives = 194/271 (71%), Gaps = 77/271 (28%)
Query: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQP 60
MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ
Sbjct: 1 MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQ- 59
Query: 61 VLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLL 120
DLEQLAKEQDKESEKQLL
Sbjct: 60 ------------------------------------------DLEQLAKEQDKESEKQLL 77
Query: 121 LQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSST 180
LQEVENHKKQML RKTTKESLAQTSST
Sbjct: 78 LQEVENHKKQML----------------------------------RKTTKESLAQTSST 103
Query: 181 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 240
ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR
Sbjct: 104 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRR 163
Query: 241 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 271
ELTDKLLIFLALALFLATVLYIVKKRLFPFL
Sbjct: 164 ELTDKLLIFLALALFLATVLYIVKKRLFPFL 194
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 41.6 bits (96), Expect = 7e-04
Identities = 49/221 (22%), Positives = 89/221 (40%), Gaps = 40/221 (18%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQPVLYQRAFIWTASTFFFKLTYS 81
E++ + + + + SG SA E+N K + +FQ++R ++ Q TA+T K S
Sbjct: 1146 ELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA--TAATLRKKQADS 1203
Query: 82 LTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKA 141
+ + +L+++ +Q E EK L E+++ + + S
Sbjct: 1204 VAELGE------------QIDNLQRV--KQKLEKEKSELKMEIDDMASNIEALSKSKSNI 1249
Query: 142 NLTCKIAID-------------------NLEKAELLQGGDLLRQRKTTKES----LAQTS 178
TC+ D N++KA L L R KES L ++
Sbjct: 1250 ERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSK 1309
Query: 179 STITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEE 219
+T+ L + R M ++ +++ AM + SSR D E
Sbjct: 1310 QALTQQLEELKRQMEEET-KAKNAMAHALQSSRHDCDLLRE 1349
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 38.9 bits (89), Expect = 0.005
Identities = 52/220 (23%), Positives = 91/220 (41%), Gaps = 23/220 (10%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQPVLYQRAFIWTASTFFFKLTYS 81
E+KA +D++D L+ +T+ + KEKF QL V R + A++ KL
Sbjct: 361 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQV---REKLKHATSKAKKLEKQ 417
Query: 82 LTDFSSTQHDFNSPTTP------VTFSDLEQLAKEQDKESEK------------QLLLQE 123
L +F S T + L KE++KE +K Q L +E
Sbjct: 418 LQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKE 477
Query: 124 VENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITE 183
E+ +K+++ S +A +A L+ L + + Q KE+L S T+ E
Sbjct: 478 KESREKELMGFSKSVNEARSKMDVAQSELD-IYLSRHNTAVSQLTKAKEALIAASETLKE 536
Query: 184 SLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 223
I R + ++ Q+E+ ++ + + FKS+
Sbjct: 537 RKAAI-RDIEGKLPQTEQELKEKEKELQKLTQEETNFKSL 575
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 38.9 bits (89), Expect = 0.005
Identities = 52/220 (23%), Positives = 91/220 (41%), Gaps = 23/220 (10%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQPVLYQRAFIWTASTFFFKLTYS 81
E+KA +D++D L+ +T+ + KEKF QL V R + A++ KL
Sbjct: 361 EMKAKNKDVKDTEKKLNKITKFIEENKEKFTQLDLEDVQV---REKLKHATSKAKKLEKQ 417
Query: 82 LTDFSSTQHDFNSPTTP------VTFSDLEQLAKEQDKESEK------------QLLLQE 123
L +F S T + L KE++KE +K Q L +E
Sbjct: 418 LQKDKEKVEEFKSIPAKSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKE 477
Query: 124 VENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITE 183
E+ +K+++ S +A +A L+ L + + Q KE+L S T+ E
Sbjct: 478 KESREKELMGFSKSVNEARSKMDVAQSELD-IYLSRHNTAVSQLTKAKEALIAASETLKE 536
Query: 184 SLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 223
I R + ++ Q+E+ ++ + + FKS+
Sbjct: 537 RKAAI-RDIEGKLPQTEQELKEKEKELQKLTQEETNFKSL 575
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 38.5 bits (88), Expect = 0.006
Identities = 44/224 (19%), Positives = 91/224 (40%), Gaps = 46/224 (20%)
Query: 7 VHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQPVLYQRA 66
V ++ C +I D E++ L ++I +S + N ++E R ++P
Sbjct: 463 VEIKNCKNQIKIRDREIEILTKEINKLELKISDFLDENEALRE-----RVGLEP------ 511
Query: 67 FIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQEVEN 126
K LT+F +++H K+Q +E Q+LL+E+E+
Sbjct: 512 ----------KTMIDLTEFRNSKH-----------------LKQQQYRAENQILLKEIES 544
Query: 127 HKKQMLSNQASWR-------KANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSS 179
+++ L + R K + T + ++L E + GD + +RK SL S
Sbjct: 545 LEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKNMSE 604
Query: 180 TITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSM 223
+++ +SR + ++ + E + + + + EE K +
Sbjct: 605 AQSKNEF-LSRELIEKERDLERSRTVIAKFQNKLKELVEENKQL 647
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
+++AK Q E+Q Q++E +++++++ R+ + + K E LQ L
Sbjct: 2522 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR--KQEELQ--QLE 2577
Query: 165 RQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 213
+QR+ +E LA+ + + E L + + SEE S V +++T+
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2626
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----E 156
++ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1850 TEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELE 1907
Query: 157 LLQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTIL 214
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L
Sbjct: 1908 RQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1967
Query: 215 DA 216
+A
Sbjct: 1968 EA 1969
Score = 28.9 bits (63), Expect = 5.0
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 104 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 163
L QL E+ + +++ LLQE + ++ LS EK LLQ
Sbjct: 2468 LLQLKSEEMQTVQQEQLLQETQALQQSFLS-------------------EKDSLLQRERF 2508
Query: 164 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQS--------EEAMQSLVTSSRTILD 215
+ Q K E L Q + L + QQ++Q EEA + + +
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2568
Query: 216 ANEEFKSMSGTIQLGRKLITKYNRR 240
EE + + + +L+ + N+R
Sbjct: 2569 KQEELQQLEQQRRQQEELLAEENQR 2593
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
+++AK Q E+Q Q++E +++++++ R+ + + K E LQ L
Sbjct: 2526 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR--KQEELQ--QLE 2581
Query: 165 RQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 213
+QR+ +E LA+ + + E L + + SEE S V +++T+
Sbjct: 2582 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2630
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----E 156
++ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1854 TEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELE 1911
Query: 157 LLQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTIL 214
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L
Sbjct: 1912 RQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1971
Query: 215 DA 216
+A
Sbjct: 1972 EA 1973
Score = 28.9 bits (63), Expect = 5.0
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 104 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 163
L QL E+ + +++ LLQE + ++ LS EK LLQ
Sbjct: 2472 LLQLKSEEMQTVQQEQLLQETQALQQSFLS-------------------EKDSLLQRERF 2512
Query: 164 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQS--------EEAMQSLVTSSRTILD 215
+ Q K E L Q + L + QQ++Q EEA + + +
Sbjct: 2513 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2572
Query: 216 ANEEFKSMSGTIQLGRKLITKYNRR 240
EE + + + +L+ + N+R
Sbjct: 2573 KQEELQQLEQQRRQQEELLAEENQR 2597
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
+++AK Q E+Q Q++E +++++++ R+ + + K E LQ L
Sbjct: 2522 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR--KQEELQ--QLE 2577
Query: 165 RQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 213
+QR+ +E LA+ + + E L + + SEE S V +++T+
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2626
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----E 156
++ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1850 TEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELE 1907
Query: 157 LLQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTIL 214
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L
Sbjct: 1908 RQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1967
Query: 215 DA 216
+A
Sbjct: 1968 EA 1969
Score = 28.9 bits (63), Expect = 5.0
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 104 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 163
L QL E+ + +++ LLQE + ++ LS EK LLQ
Sbjct: 2468 LLQLKSEEMQTVQQEQLLQETQALQQSFLS-------------------EKDSLLQRERF 2508
Query: 164 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQS--------EEAMQSLVTSSRTILD 215
+ Q K E L Q + L + QQ++Q EEA + + +
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2568
Query: 216 ANEEFKSMSGTIQLGRKLITKYNRR 240
EE + + + +L+ + N+R
Sbjct: 2569 KQEELQQLEQQRRQQEELLAEENQR 2593
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
+++AK Q E+Q Q++E +++++++ R+ + + K E LQ L
Sbjct: 2490 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR--KQEELQ--QLE 2545
Query: 165 RQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 213
+QR+ +E LA+ + + E L + + SEE S V +++T+
Sbjct: 2546 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2594
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----E 156
++ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1818 TEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELE 1875
Query: 157 LLQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTIL 214
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L
Sbjct: 1876 RQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1935
Query: 215 DA 216
+A
Sbjct: 1936 EA 1937
Score = 28.9 bits (63), Expect = 5.0
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 104 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 163
L QL E+ + +++ LLQE + ++ LS EK LLQ
Sbjct: 2436 LLQLKSEEMQTVQQEQLLQETQALQQSFLS-------------------EKDSLLQRERF 2476
Query: 164 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQS--------EEAMQSLVTSSRTILD 215
+ Q K E L Q + L + QQ++Q EEA + + +
Sbjct: 2477 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2536
Query: 216 ANEEFKSMSGTIQLGRKLITKYNRR 240
EE + + + +L+ + N+R
Sbjct: 2537 KQEELQQLEQQRRQQEELLAEENQR 2561
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
+++AK Q E+Q Q++E +++++++ R+ + + K E LQ L
Sbjct: 2659 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR--KQEELQ--QLE 2714
Query: 165 RQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 213
+QR+ +E LA+ + + E L + + SEE S V +++T+
Sbjct: 2715 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2763
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----E 156
++ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1987 TEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELE 2044
Query: 157 LLQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTIL 214
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L
Sbjct: 2045 RQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAEL 2104
Query: 215 DA 216
+A
Sbjct: 2105 EA 2106
Score = 28.9 bits (63), Expect = 5.0
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 104 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 163
L QL E+ + +++ LLQE + ++ LS EK LLQ
Sbjct: 2605 LLQLKSEEMQTVQQEQLLQETQALQQSFLS-------------------EKDSLLQRERF 2645
Query: 164 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQS--------EEAMQSLVTSSRTILD 215
+ Q K E L Q + L + QQ++Q EEA + + +
Sbjct: 2646 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2705
Query: 216 ANEEFKSMSGTIQLGRKLITKYNRR 240
EE + + + +L+ + N+R
Sbjct: 2706 KQEELQQLEQQRRQQEELLAEENQR 2730
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
+++AK Q E+Q Q++E +++++++ R+ + + K E LQ L
Sbjct: 2500 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR--KQEELQ--QLE 2555
Query: 165 RQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 213
+QR+ +E LA+ + + E L + + SEE S V +++T+
Sbjct: 2556 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2604
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----E 156
++ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1828 TEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELE 1885
Query: 157 LLQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTIL 214
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L
Sbjct: 1886 RQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1945
Query: 215 DA 216
+A
Sbjct: 1946 EA 1947
Score = 28.9 bits (63), Expect = 5.0
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 104 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 163
L QL E+ + +++ LLQE + ++ LS EK LLQ
Sbjct: 2446 LLQLKSEEMQTVQQEQLLQETQALQQSFLS-------------------EKDSLLQRERF 2486
Query: 164 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQS--------EEAMQSLVTSSRTILD 215
+ Q K E L Q + L + QQ++Q EEA + + +
Sbjct: 2487 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2546
Query: 216 ANEEFKSMSGTIQLGRKLITKYNRR 240
EE + + + +L+ + N+R
Sbjct: 2547 KQEELQQLEQQRRQQEELLAEENQR 2571
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
+++AK Q E+Q Q++E +++++++ R+ + + K E LQ L
Sbjct: 2508 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR--KQEELQ--QLE 2563
Query: 165 RQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 213
+QR+ +E LA+ + + E L + + SEE S V +++T+
Sbjct: 2564 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2612
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----E 156
++ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1836 TEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELE 1893
Query: 157 LLQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTIL 214
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L
Sbjct: 1894 RQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1953
Query: 215 DA 216
+A
Sbjct: 1954 EA 1955
Score = 28.9 bits (63), Expect = 5.0
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 104 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 163
L QL E+ + +++ LLQE + ++ LS EK LLQ
Sbjct: 2454 LLQLKSEEMQTVQQEQLLQETQALQQSFLS-------------------EKDSLLQRERF 2494
Query: 164 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQS--------EEAMQSLVTSSRTILD 215
+ Q K E L Q + L + QQ++Q EEA + + +
Sbjct: 2495 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2554
Query: 216 ANEEFKSMSGTIQLGRKLITKYNRR 240
EE + + + +L+ + N+R
Sbjct: 2555 KQEELQQLEQQRRQQEELLAEENQR 2579
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 37.7 bits (86), Expect = 0.011
Identities = 26/109 (23%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
+++AK Q E+Q Q++E +++++++ R+ + + K E LQ L
Sbjct: 2549 DEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR--KQEELQ--QLE 2604
Query: 165 RQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTI 213
+QR+ +E LA+ + + E L + + SEE S V +++T+
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTL 2653
Score = 33.9 bits (76), Expect = 0.15
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKA-----E 156
++ E KE++ E+E+ L E E +++ L QA+ KA++ ++A L KA E
Sbjct: 1877 TEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLA--QLRKASDSELE 1934
Query: 157 LLQG--GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTIL 214
+G D LRQR+ +E + ++ ++ G + + + + A +L + + L
Sbjct: 1935 RQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAEL 1994
Query: 215 DA 216
+A
Sbjct: 1995 EA 1996
Score = 28.9 bits (63), Expect = 5.0
Identities = 32/145 (22%), Positives = 55/145 (37%), Gaps = 27/145 (18%)
Query: 104 LEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDL 163
L QL E+ + +++ LLQE + ++ LS EK LLQ
Sbjct: 2495 LLQLKSEEMQTVQQEQLLQETQALQQSFLS-------------------EKDSLLQRERF 2535
Query: 164 LRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQS--------EEAMQSLVTSSRTILD 215
+ Q K E L Q + L + QQ++Q EEA + + +
Sbjct: 2536 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2595
Query: 216 ANEEFKSMSGTIQLGRKLITKYNRR 240
EE + + + +L+ + N+R
Sbjct: 2596 KQEELQQLEQQRRQQEELLAEENQR 2620
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 37.0 bits (84), Expect = 0.018
Identities = 47/237 (19%), Positives = 99/237 (41%), Gaps = 25/237 (10%)
Query: 12 CNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKV---KEKFQQLRHRIQPVLYQRAFI 68
C Q+I + +LEV Q I+ + L + +KV +EK L+ +++
Sbjct: 314 CQQKIKELELEVLKHTQSIKSQNNLQEKLVQEKSKVADAEEKILDLQRKLEHA------- 366
Query: 69 WTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQEVENHK 128
K+ + T S Q T ++ + + Q+++ +++LL Q V+
Sbjct: 367 -------HKVCLTDTCISEKQ-QLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELH 418
Query: 129 KQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGI 188
+Q+ + Q +TC + +++ + Q LL+Q + K + + E +
Sbjct: 419 RQVRTLQDKENLLEMTC-----SQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKL 473
Query: 189 SRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDK 245
S++ ++ EE ++ L + + + NE+ +Q + +T N EL DK
Sbjct: 474 SKLQQEKEALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLT--NEVELRDK 528
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 36.6 bits (83), Expect = 0.024
Identities = 40/197 (20%), Positives = 77/197 (39%), Gaps = 20/197 (10%)
Query: 30 IRDCSGPLSALTE-------LNTKVKEKFQQLRHRIQPVLYQRAFIWTASTFFFKLTYSL 82
I D G + L E L KV+ + +QL+ R + +++ + T+ K+
Sbjct: 641 INDLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQS 700
Query: 83 TDFSSTQHDFNSPTTP---VTFSDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWR 139
+ +H + +E+ E KE EK+LL + K + L +A R
Sbjct: 701 LEQEEAEHKATKARLADKNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKR 760
Query: 140 KANLTCKIAIDNLEKAELLQGGDLLR----------QRKTTKESLAQTSSTITESLMGIS 189
+ L C + + ELL+ D+L +++T K L Q + +
Sbjct: 761 CSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTL 820
Query: 190 RMMAQQVQQSEEAMQSL 206
+M +Q++Q + +
Sbjct: 821 KMSEKQLKQENNHLMEM 837
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 34.3 bits (77), Expect = 0.12
Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 15/148 (10%)
Query: 112 DKESEKQLLLQEVENHKKQMLS------------NQASWRKANLTCKIAIDNLEKAELLQ 159
D + E++ L QE+E +KQ L Q + +L KI + +KA L +
Sbjct: 1772 DLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQR 1831
Query: 160 GGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQ---QVQQSEEAMQSLVTSSRTILDA 216
D L + K+T E+ + + I + Q Q + EEA++ + +
Sbjct: 1832 LEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSERE 1891
Query: 217 NEEFKSMSGTIQLGRKLITKYNRRELTD 244
+S +Q K I + RR+L D
Sbjct: 1892 KNSLRSEIERLQAEIKRIEERCRRKLED 1919
Score = 33.9 bits (76), Expect = 0.15
Identities = 41/224 (18%), Positives = 97/224 (43%), Gaps = 17/224 (7%)
Query: 10 RICNQEIVK----FDLEVKALIQD-IRDCSGPLSALTELNTKVKEKFQQLRHRIQPVLYQ 64
+ C EI++ ++E+K ++Q D + +L E +++K +++ +
Sbjct: 1278 KACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEE 1337
Query: 65 RAFIWTASTFFFKLTYSLTD-FSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQE 123
W K+ + + S ++ F + +T + + QL + KE + +
Sbjct: 1338 AKRRWEYENELSKVRNNYDEEIISLKNQFETEIN-ITKTTIHQLTMQ--KEEDTSGYRAQ 1394
Query: 124 VENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITE 183
++N ++ S ++ T +NL + E + ++Q+K T ++Q +
Sbjct: 1395 IDNLTRENRSLSEEIKRLKNTLTQTTENLRRVE-----EDIQQQKATGSEVSQRKQQLEV 1449
Query: 184 SLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTI 227
L +++M + ++S QSL +++TI D N+E + + I
Sbjct: 1450 ELRQVTQM---RTEESVRYKQSLDDAAKTIQDKNKEIERLKQLI 1490
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 34.3 bits (77), Expect = 0.12
Identities = 45/219 (20%), Positives = 96/219 (43%), Gaps = 36/219 (16%)
Query: 22 EVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQPVLYQRAFIWTASTFFFKLTYS 81
E++ + + + + G S E+N K + +FQ++R ++ Q TA+ K S
Sbjct: 1142 ELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEA--TAAALRKKHADS 1199
Query: 82 LTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKE-SEKQLLLQEVENHKKQMLSNQASWRK 140
+ + +L+++ ++ +KE SE +L L +V ++ +Q++ +A+ K
Sbjct: 1200 VAELGE------------QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK 1247
Query: 141 ANLTCKIAI-DNLEKAELLQ----------------GGDLLRQ---RKTTKESLAQTSST 180
T + + ++ KAE Q G+L RQ ++ L + T
Sbjct: 1248 MCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLT 1307
Query: 181 ITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEE 219
T+ L + R + ++V +++ A+ + S+R D E
Sbjct: 1308 YTQQLEDLKRQLEEEV-KAKNALAHALQSARHDCDLLRE 1345
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 34.3 bits (77), Expect = 0.12
Identities = 35/174 (20%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Query: 77 KLTYS-LTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQ 135
K+ Y+ + F + F + + EQ K E E + QE + KK++ + Q
Sbjct: 969 KVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQ 1028
Query: 136 ASWRKANLTCKIAIDNLEKAELLQGGDLLRQRK----------TTKESLAQTSSTITESL 185
R + + + + +E+A + +L +Q K KE L + ++ T +
Sbjct: 1029 KDLRDKTVLIEKSHE-MERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEI 1087
Query: 186 MGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNR 239
+ + ++ +Q E+ + + TI + EE KSM + ++ +TK ++
Sbjct: 1088 LAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQ 1141
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 34.3 bits (77), Expect = 0.12
Identities = 35/174 (20%), Positives = 74/174 (42%), Gaps = 12/174 (6%)
Query: 77 KLTYS-LTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQ 135
K+ Y+ + F + F + + EQ K E E + QE + KK++ + Q
Sbjct: 982 KVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQ 1041
Query: 136 ASWRKANLTCKIAIDNLEKAELLQGGDLLRQRK----------TTKESLAQTSSTITESL 185
R + + + + +E+A + +L +Q K KE L + ++ T +
Sbjct: 1042 KDLRDKTVLIEKSHE-MERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEI 1100
Query: 186 MGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNR 239
+ + ++ +Q E+ + + TI + EE KSM + ++ +TK ++
Sbjct: 1101 LAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQ 1154
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 33.5 bits (75), Expect = 0.20
Identities = 48/219 (21%), Positives = 96/219 (43%), Gaps = 23/219 (10%)
Query: 15 EIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQPVLYQRAFIWTASTF 74
E+ EV+ L ++I+D S L +T K+ + R+Q +L +
Sbjct: 748 ELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEE------IGKT 801
Query: 75 FFKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQEVENHKK--QML 132
L + +++ ST +F + T D EQ K +E+E+ + QE+ N K Q
Sbjct: 802 KDDLATTQSNYKSTDQEFQNFKT--LHMDFEQKYKMVLEENER--MNQEIVNLSKEAQKF 857
Query: 133 SNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMM 192
+ K L+ K + EK +Q + L + + KE L ST+ +++ ++
Sbjct: 858 DSSLGALKTELSYKTQ-ELQEKTREVQ--ERLNEMEQLKEQLENRDSTL-QTVEREKTLI 913
Query: 193 AQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGR 231
+++QQ+ E + +T+ ++ K + ++Q+ R
Sbjct: 914 TEKLQQTLEEV-------KTLTQEKDDLKQLQESLQIER 945
Score = 28.5 bits (62), Expect = 6.5
Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 12/105 (11%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGG--- 161
+QL Q++ SE Q + E+EN K ++ + + + + + LE A+ L
Sbjct: 1141 QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE------HMETERLELAQKLNENYEE 1194
Query: 162 --DLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQ 204
+ ++RK KE L ++ T + L G R + Q++E ++
Sbjct: 1195 VKSITKERKVLKE-LQKSFETERDHLRGYIREIEATGLQTKEELK 1238
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 33.1 bits (74), Expect = 0.26
Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
E+L + K +E + L+E+E HK Q L W+ + + K + + L
Sbjct: 95 EKLETLRLKRAEDKAKLKELEKHKIQ-LEQVQEWKSKMQEQQADLQRRLKEARKEAKEAL 153
Query: 165 RQRKTTKESLAQTSSTITESLMG--ISRMMAQQVQQSEEAMQSLV---TSSRTILDANEE 219
++ E +A T+ I + + ++ A+ +QQ EA++ V T+ IL A E
Sbjct: 154 EAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIE 213
Query: 220 FKSMSG 225
K G
Sbjct: 214 EKGSDG 219
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 33.1 bits (74), Expect = 0.26
Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
E+L + K +E + L+E+E HK Q L W+ + + K + + L
Sbjct: 209 EKLETLRLKRAEDKAKLKELEKHKIQ-LEQVQEWKSKMQEQQADLQRRLKEARKEAKEAL 267
Query: 165 RQRKTTKESLAQTSSTITESLMG--ISRMMAQQVQQSEEAMQSLV---TSSRTILDANEE 219
++ E +A T+ I + + ++ A+ +QQ EA++ V T+ IL A E
Sbjct: 268 EAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIE 327
Query: 220 FKSMSG 225
K G
Sbjct: 328 EKGSDG 333
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 33.1 bits (74), Expect = 0.26
Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
E+L + K +E + L+E+E HK Q L W+ + + K + + L
Sbjct: 95 EKLETLRLKRAEDKAKLKELEKHKIQ-LEQVQEWKSKMQEQQADLQRRLKEARKEAKEAL 153
Query: 165 RQRKTTKESLAQTSSTITESLMG--ISRMMAQQVQQSEEAMQSLV---TSSRTILDANEE 219
++ E +A T+ I + + ++ A+ +QQ EA++ V T+ IL A E
Sbjct: 154 EAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIE 213
Query: 220 FKSMSG 225
K G
Sbjct: 214 EKGSDG 219
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 33.1 bits (74), Expect = 0.26
Identities = 31/126 (24%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 105 EQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLL 164
E+L + K +E + L+E+E HK Q L W+ + + K + + L
Sbjct: 229 EKLETLRLKRAEDKAKLKELEKHKIQ-LEQVQEWKSKMQEQQADLQRRLKEARKEAKEAL 287
Query: 165 RQRKTTKESLAQTSSTITESLMG--ISRMMAQQVQQSEEAMQSLV---TSSRTILDANEE 219
++ E +A T+ I + + ++ A+ +QQ EA++ V T+ IL A E
Sbjct: 288 EAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTDLEILKAEIE 347
Query: 220 FKSMSG 225
K G
Sbjct: 348 EKGSDG 353
>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
Length = 783
Score = 33.1 bits (74), Expect = 0.26
Identities = 42/199 (21%), Positives = 84/199 (42%), Gaps = 17/199 (8%)
Query: 42 ELNTKVKEKFQQLRHRIQPVLYQRAFIWTASTFFFKLTYSLTDFSSTQHDFNSPTTPVTF 101
ELN +KE+ + R R+Q V+ + + +T TQ +
Sbjct: 382 ELNATLKEEMRMFRMRVQEVVKENEELHQELNKSSAVTSEEWRQLQTQAKLVLEENKLLL 441
Query: 102 SDLE-QLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQG 160
LE Q K +D E+ LQEV KQ++ +A K + K +N E+ E+L+
Sbjct: 442 EQLEIQQRKAKDSHQER---LQEVSKLTKQLMLLEA---KTHGQEKELAENREQLEILRA 495
Query: 161 GDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEF 220
+ ++ S + + + +S++ + Q+ ++ E A + T+L A ++
Sbjct: 496 ----KCQELKTHSDGKIAVEVHKSIVNELKSQLQKEEEKERAEMEELMEKLTVLQAQKK- 550
Query: 221 KSMSGTIQLGRKLITKYNR 239
++ L + +T+ N+
Sbjct: 551 -----SLLLEKNSLTEQNK 564
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 32.7 bits (73), Expect = 0.34
Identities = 44/230 (19%), Positives = 88/230 (38%), Gaps = 19/230 (8%)
Query: 16 IVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQPVLYQRAFIWTASTFF 75
I K EVK+L+ + SA + N K+ ++L + A I + + +
Sbjct: 591 ISKMKSEVKSLVNRSKQLE---SAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYM 647
Query: 76 FKLTYSLTDFSSTQHDFNSPTTPVTFSDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQ 135
+ +Q + + + QDKE E LQ+ E KK +
Sbjct: 648 QNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQM 707
Query: 136 ASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTI---TESLMGISRMM 192
S R+A+ + +L + D + +++ + + + + E L +
Sbjct: 708 ESHREAH-----------QKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKL 756
Query: 193 AQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRREL 242
+ Q+ E ++ L+ + A E+ K + T+ R+L T +N R+L
Sbjct: 757 KIEDQEREMKLEKLLLLNDKREQAREDLKGLEETV--SRELQTLHNLRKL 804
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 32.7 bits (73), Expect = 0.34
Identities = 34/138 (24%), Positives = 58/138 (42%), Gaps = 21/138 (15%)
Query: 102 SDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGG 161
S E+ KE++KE+EK+ EVEN K+ +L + DN EK + G
Sbjct: 516 SQEEKDEKEKEKEAEKEEEKPEVENDKEDLLKEKTDDTSGE-------DNDEKEAVASKG 568
Query: 162 DLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFK 221
+ T S + IT R MA + SEEA+ ++ ++ NE +
Sbjct: 569 ------RKTANSQGRRKGRIT-------RSMANEA-NSEEAITPQQSAELASMELNESSR 614
Query: 222 SMSGTIQLGRKLITKYNR 239
++ +K + ++ R
Sbjct: 615 WTEEEMETAKKGLLEHGR 632
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.130 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,249,721
Number of Sequences: 37866
Number of extensions: 305184
Number of successful extensions: 1984
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 114
Number of HSP's that attempted gapping in prelim test: 1849
Number of HSP's gapped (non-prelim): 254
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.