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Search of human proteins with 153792112
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153792112 PRAME family member 20 [Homo sapiens]
(475 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153792112 PRAME family member 20 [Homo sapiens] 966 0.0
gi|153945800 PRAME family member 21 [Homo sapiens] 966 0.0
gi|61696142 PRAME family member 5 [Homo sapiens] 790 0.0
gi|58219004 PRAME family member 6 [Homo sapiens] 790 0.0
gi|148356236 PRAME family member 15 [Homo sapiens] 788 0.0
gi|61102721 PRAME family member 9 [Homo sapiens] 788 0.0
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 785 0.0
gi|59958373 PRAME family member 4 [Homo sapiens] 782 0.0
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 769 0.0
gi|226437621 PRAME family member 11 [Homo sapiens] 699 0.0
gi|88942379 PREDICTED: PRAME family member [Homo sapiens] 630 0.0
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 626 e-179
gi|124249372 PRAME family member 12 [Homo sapiens] 572 e-163
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 566 e-161
gi|59676593 PRAME family member 7 [Homo sapiens] 565 e-161
gi|59676587 PRAME family member 8 [Homo sapiens] 565 e-161
gi|154800493 PRAME family member 22 [Homo sapiens] 462 e-130
gi|153791443 PRAME family member 18 [Homo sapiens] 458 e-129
gi|194306638 PRAME family member 3 [Homo sapiens] 456 e-128
gi|194306635 PRAME family member 19 [Homo sapiens] 454 e-128
gi|157426839 PRAME family member 17 [Homo sapiens] 444 e-125
gi|113865933 PRAME family member 16 [Homo sapiens] 444 e-125
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 437 e-122
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 437 e-122
gi|46249369 preferentially expressed antigen in melanoma [Homo s... 437 e-122
gi|46249367 preferentially expressed antigen in melanoma [Homo s... 437 e-122
gi|5174641 preferentially expressed antigen in melanoma [Homo sa... 437 e-122
gi|66954681 PRAME family member 13 [Homo sapiens] 429 e-120
gi|12738831 PRAME family member 1 [Homo sapiens] 426 e-119
gi|194018546 PRAME family member 10 [Homo sapiens] 424 e-119
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 966 bits (2497), Expect = 0.0
Identities = 475/475 (100%), Positives = 475/475 (100%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI
Sbjct: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
Query: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG
Sbjct: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
Query: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD
Sbjct: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
Query: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC
Sbjct: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 966 bits (2497), Expect = 0.0
Identities = 475/475 (100%), Positives = 475/475 (100%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
Query: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI
Sbjct: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
Query: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG
Sbjct: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
Query: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD
Sbjct: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
Query: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC
Sbjct: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 790 bits (2040), Expect = 0.0
Identities = 392/476 (82%), Positives = 418/476 (87%), Gaps = 1/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPL L+K PC E FQAVLDGLDALLT V RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C NA N+KPVQDCPRMRGQQPLTVF++L LKNRTLDEY TCL LWVKQR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+D SRY+SPEQKKE VTQFTTQFLKL CLQKL MNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQVNAILPALSRCFEL TFSF GNPIS ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
D G +C SRFAQ+ AELM RVR LR P+RILFCTD CP CGNRS YDLE D+CCC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 790 bits (2039), Expect = 0.0
Identities = 392/476 (82%), Positives = 418/476 (87%), Gaps = 1/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPL L+K PC E FQAVLDGLDALLT V RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
AR C NA N+ PVQDCPRMRGQQPLTVF++L LKNRTLDEY TCL LWVKQR+ L+HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+D SRY+SPEQKKE VTQFTTQFLKL CLQKL MNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQVNAILPALSRCFEL TFSF GNPIS ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
D G +C SRFAQ+ AELM RVR LR P+RILFCTD CP CGNRS YDLE D+CCC
Sbjct: 421 DADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 788 bits (2035), Expect = 0.0
Identities = 391/476 (82%), Positives = 418/476 (87%), Gaps = 1/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPL L+K PC E FQAVLDGLDALLT VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C NA N+KPVQDCPRMRG+QPLTVF++L LKNRTLDEY T L LWVKQR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
G +C SRFAQ+ AELM RVR LR P+RILFCTDYCP CGNRS YDLE D+ CC
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 788 bits (2035), Expect = 0.0
Identities = 391/476 (82%), Positives = 418/476 (87%), Gaps = 1/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPL L+K PC E FQAVLDGLDALLT VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C NA N+KPVQDCPRMRG+QPLTVF++L LKNRTLDEY T L LWVKQR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 242
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 302
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
G +C SRFAQ+ AELM RVR LR P+RILFCTDYCP CGNRS YDLE D+ CC
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 785 bits (2027), Expect = 0.0
Identities = 390/476 (81%), Positives = 416/476 (87%), Gaps = 1/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIRTPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPL L+K PC E FQAVLDGLDALLT V RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C NA N+KPVQDCPRMRGQQPLTVF++L LKNRTLDEY TCL LWVKQR+ L+HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KLVLS
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLS 240
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+D SRY+SPEQKKE VTQFTTQFLKL CLQKL MNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 241 HMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKVLT 300
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 301 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 360
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQVNAILPALS CFEL TFSF GNPIS ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 361 GIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRESY 420
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
D G +C SRF Q+ AELM RVR LR P+RILFCTD CP CGNRS YDLE D+CCC
Sbjct: 421 DADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQCCC 476
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 782 bits (2020), Expect = 0.0
Identities = 387/476 (81%), Positives = 416/476 (87%), Gaps = 1/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSI TPPRLLELAGRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPL L+K PC E FQAVLDGLDALL VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C NA N+KPV+DCPRMRG+QPLTVF++L LKNRTLDEY TCL LWVKQR+ L+HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG MRNL+KL+LS
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLILS 242
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL L
Sbjct: 243 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKFLT 302
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 303 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 362
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL HTI L NLC+ELYPAPRESY
Sbjct: 363 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRESY 422
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
G +C SRFAQ+ AELM RVR LR P+RILFCTDYCP CGNRS YDLE D+ CC
Sbjct: 423 GADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLEADQYCC 478
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 769 bits (1986), Expect = 0.0
Identities = 383/476 (80%), Positives = 412/476 (86%), Gaps = 1/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIR PPRLLEL GRSLLRD+ALA+STLEELPTELFPPLFMEAFSRR CEALKLMVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPL L+K PC E FQAVLDGLDALLT VR RRWKLQVLDLQDV ENFWMVWSEAM
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C NA N+ PVQDCPRMR +QPLTVF++L LKNRTLDEY TCL LWVKQR L+HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+L +FTPYLG +RNL+KLVLS
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPILTQFTPYLGHLRNLQKLVLS 277
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 278 HMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 337
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 338 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 397
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL HTI L NLCLELYPAP+ESY
Sbjct: 398 GIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQESY 457
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
G +C SRFAQ+ AELM +VR LR P+RILFCTD CP G+RS YDLE D+ CC
Sbjct: 458 GADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPDHGDRSFYDLEADQYCC 513
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 699 bits (1805), Expect = 0.0
Identities = 347/436 (79%), Positives = 374/436 (85%), Gaps = 1/436 (0%)
Query: 41 MEAFSRRHCEALKLMVQAWPFLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKL 100
MEAFSRR CEALKLMVQAWPF RLPL L+K PC E FQAVLDGLDALLT VR RRWKL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 101 QVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTL 160
QVLDLQDV ENFWMVWSEAMA C NA N+ PVQDCPRMR +QPLTVF++L LKNRTL
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 161 DEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPV 220
DEY TCL LWVKQR L+HLCCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC W LP+
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWILPI 180
Query: 221 LAEFTPYLGQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSF 279
L +FTPYLG +RNL+KLVLS +D SRY+SPEQKKE VTQFTTQFLKLRCLQKLYMNSVSF
Sbjct: 181 LTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSF 240
Query: 280 LEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVP 339
LEGHLDQ+LSCLKTSL +L ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVP
Sbjct: 241 LEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVP 300
Query: 340 LQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLC 399
LQ+LLEKVAATLEYLDLDDCGI+DSQVNAILPALSRCFEL TFSF GNPI ATLENLL
Sbjct: 301 LQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLS 360
Query: 400 HTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQ 459
HTI L NLCLELYPAP+ESY G +C SRFAQ+ AELM +VR LR P+RILFCTD CP
Sbjct: 361 HTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCPD 420
Query: 460 CGNRSLYDLEVDRCCC 475
G+RS YDLE D+ CC
Sbjct: 421 HGDRSFYDLEADQYCC 436
>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
Length = 395
Score = 630 bits (1626), Expect = 0.0
Identities = 309/381 (81%), Positives = 333/381 (87%), Gaps = 1/381 (0%)
Query: 96 RRWKLQVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCL 155
RRWKLQVLDLQDV ENFWMVWSEAMAR C NA N+KPVQDCPRMRG+QPLTVF++L L
Sbjct: 15 RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
Query: 156 KNRTLDEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCN 215
KNRTLDE+ TCL LWVKQR+ L+HLCCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC
Sbjct: 75 KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
Query: 216 WTLPVLAEFTPYLGQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYM 274
W LP+L +FTPYLG MRNL+KLVLS +D SRY+SPEQKKE VTQFTTQFLKL CLQKLYM
Sbjct: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
Query: 275 NSVSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLAN 334
NSVSFLEGHLDQ+LSCLKTSL +L ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N
Sbjct: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
Query: 335 FSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATL 394
+SLVPLQ+LLEKVAATLEYLDLDDCGI+DSQVNAILPALSRCFEL TFSF GNPIS ATL
Sbjct: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
Query: 395 ENLLCHTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCT 454
ENLL HTI L NLCLELYPAPRESY G +C SRF Q+ AELM RVR LR P+RILF T
Sbjct: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
Query: 455 DYCPQCGNRSLYDLEVDRCCC 475
DYCP CGNRS YDLE D+ CC
Sbjct: 375 DYCPDCGNRSFYDLEADQYCC 395
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 626 bits (1614), Expect = e-179
Identities = 322/476 (67%), Positives = 366/476 (76%), Gaps = 3/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F LPLGSLMK P E V+DG+D LL +VR RR KLQVL+L+DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK + +DE + WV+ R G VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
CC K+ M N RNIL+TV D IQ +E+ N W ++ EF+PYL QMRNLRKL +
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSPYLSQMRNLRKLFI 239
Query: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
SD RY+ +E + FTTQFLKL CLQKLYMNSVSFLEGHLDQ+LSCLKTSL +L
Sbjct: 240 SD-GCRYLLSSDSQEQIAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLT 298
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N+SLVPLQ+LLEKVAATLEYLDLDDC
Sbjct: 299 ITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDC 358
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQVNAILPALSRCFEL TFSF GNPIS ATLENLL HTI L NLCLELYPAPRESY
Sbjct: 359 GIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESY 418
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
G +C SRF Q+ AELM RVR LR P+RILF TDYCP CGNRS YDLE D+ CC
Sbjct: 419 GADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 474
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 572 bits (1475), Expect = e-163
Identities = 301/480 (62%), Positives = 355/480 (73%), Gaps = 7/480 (1%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS++ PPRLLELA +SLLRD ALAI TLEELP ELFPPLFMEAF+RR CE L MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F LPLGSLMK E F+AVL+GLDALL +VR RRWKLQVLDL++V ENFW +WS A
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A P A+ R+ +CPR GQQPL V +DLC KN LDE T W KQR+GL+H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCK+L++ G+ H I +L TV LDCIQEVEV C W L +L F PYLGQMRNLRKLVL
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCPWELSILIRFAPYLGQMRNLRKLVLF 238
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+I S I ++K++FV QFT+QFLKL QKLYM+SVSFLEGHLDQ+L CL+ L +
Sbjct: 239 NIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQAPLETVV 298
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T C+L ESDLKHLS PSI QLK LDL G L +FS PL VLLE+ ATL+ LDL+DC
Sbjct: 299 MTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQTLDLEDC 358
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GIVDSQ++AILPALSRC +L+TFSF GN IS A LENLL HT+ L+ L LELYPAP ESY
Sbjct: 359 GIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC----CC 475
D +G +C RF+QLGAELM +R LR+P+ I+F T CP+CG R+ YDLE C CC
Sbjct: 419 DAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHCLLNACC 478
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 566 bits (1459), Expect = e-161
Identities = 296/476 (62%), Positives = 356/476 (74%), Gaps = 3/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIR PPRLLELA + LLRD+ALAIST+EELP ELFP LFMEAFSRR CE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPLGSLMK P E+ ++VL+G+D LLT VR R+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A P A+ ++ +CP QQP VFIDLCLKNRTLDE T L W KQR+GL+H+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCK+L++ GM H+I +L V LDCIQEVEV C W L L +F PYLGQMRNLRKLVL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+I S I P+ K +F+ +FT+QFLKL Q L M+SVSFLEGHLDQ+L CL+ SL ++
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T+C+L ESDLKHLS PSI QLK LDL G L +FS PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQ++AILP LSRC +L+TFSF GN IS A LENLL HT+ L+ L LELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
D +G +C RFA+LGAELM +R LR+P+ I+FCT CP+CG R+ YDLE C C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 565 bits (1456), Expect = e-161
Identities = 296/476 (62%), Positives = 355/476 (74%), Gaps = 3/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIR PPRLLELA + LLRD+ALAIST+EELP ELFP LFMEAFSRR CE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPLGSLMK P E+ ++VL+G+D LLT VR R+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A P A+ ++ +CP QQP VFIDLCLKNRTLDE T L W KQR+GL+H+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CCK+L++ GM H+I +L V LDCIQEVEV C W L L +F PYLGQMRNLRKLVL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+I S I P+ K +F+ +FT+QFLKL Q L M+SVSFLEGHLDQ+L CL+ SL ++
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T+C+L ESDLKHLS PSI QLK LDL G L +FS PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQ++AILP LSRC +L+TFSF GN IS A LENLL HT+ L+ L LELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
D +G +C RFA+LGAELM R LR+P+ I+FCT CP+CG R+ YDLE C C
Sbjct: 419 DTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 565 bits (1455), Expect = e-161
Identities = 295/476 (61%), Positives = 356/476 (74%), Gaps = 3/476 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSIR PPRLLELA + LLRD+ALAIST+EELP ELFP LFMEAFSRR CE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F RLPLGSLMK P E+ ++VL+G+D LLT VR R+ KLQVLDL++V ENF ++S A
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A P A+ ++ +CP QQP VFIDLCLKNRTLDE T L W KQR+GL+H+
Sbjct: 121 AS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CC++L++ GM H+I +L V LDCIQEVEV C W L L +F PYLGQMRNLRKLVL
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCPWELSTLVKFAPYLGQMRNLRKLVLF 238
Query: 241 DID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
+I S I P+ K +F+ +FT+QFLKL Q L M+SVSFLEGHLDQ+L CL+ SL ++
Sbjct: 239 NIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASLEMVV 298
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T+C+L ESDLKHLS PSI QLK LDL G L +FS PL LLE+V ATL+ LDL+DC
Sbjct: 299 MTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLDLEDC 358
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI+DSQ++AILP LSRC +L+TFSF GN IS A LENLL HT+ L+ L LELYPAP ESY
Sbjct: 359 GIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAPLESY 418
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCCC 475
D +G +C RFA+LGAELM +R LR+P+ I+FCT CP+CG R+ YDLE C C
Sbjct: 419 DTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCLC 474
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 462 bits (1189), Expect = e-130
Identities = 253/474 (53%), Positives = 314/474 (66%), Gaps = 2/474 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F LPLGSLMK P E V+DG+D LL +VR RRWKLQVL+L+DV ENFW +WS A
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK + +DE + WV+ R G VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
CC K+ M N RNIL+TV D IQ +E+ N W ++ EF+ YL QMRNLRKL +
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFSRYLSQMRNLRKLFI 241
Query: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
SD +S + +++ V +F++ L+L LQ LY+ V F GHLDQ++ CL++ L LA
Sbjct: 242 SDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T L + DLK L +YPS+ QLK L+LS L L PL+ LLEKVAATL+ L L DC
Sbjct: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI DS++ ILPALS C LTTF F GN S L++LL HT RL+NL LE YPAPRES
Sbjct: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473
D RG V L AELM +R +REP+RI F CP CG LE + C
Sbjct: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 458 bits (1178), Expect = e-129
Identities = 255/474 (53%), Positives = 312/474 (65%), Gaps = 2/474 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS + P RLLELAG+SLLRD+ALAIS L+ELP ELFP LF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F LPLGSLMK P E V+DG+D LL +VR RRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK +++DE + WV+ R VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
CC K+ M N RNIL+TV D IQ +E+ N W ++AE + YL QM+NLRKL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
Query: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
SD S E + + V +F++ FL+L LQ LYM + F EG+LDQ++ CLK+ L LA
Sbjct: 240 SDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLA 299
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T L E DLK L YPS+ QLK L+LS L L PL+ LLEKVAATL+ L L DC
Sbjct: 300 LTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDC 359
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI DS++ ILPALSRC LTTF F GN S L++LL HT RL+NL LE YPAPRES
Sbjct: 360 GIGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 419
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473
D RG V L AELM +R +REP RI F CP CG LE + C
Sbjct: 420 DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 456 bits (1173), Expect = e-128
Identities = 252/474 (53%), Positives = 312/474 (65%), Gaps = 2/474 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS++ P RLLELAG+SLL D+ALAIS L+ELP ELFPPLF+EAF+ R CE LK+MVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F LPLGSLMK P E V+DG+D LL +VR RR KLQVL+L+DV ENFW +WS A
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK + +DE + WV+ R G VHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
CC K+ M N RNIL+TV D IQ +E+ N W ++ EF YL QMRNLRKL +
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPC-MIVEFIRYLSQMRNLRKLFI 241
Query: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
SD +S + +++ V +F++ L+L LQ LY+ V F GHLDQ++ CL++ L LA
Sbjct: 242 SDGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLA 301
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T L + DLK L +YPS+ QLK L+LS L L PL+ LLEKVAATL+ L L DC
Sbjct: 302 LTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDC 361
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI DS++ ILPALS C LTTF F GN S L++LL HT RL+NL LE YPAPRES
Sbjct: 362 GIRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 421
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473
D RG V L AELM +R +REP+RI F CP CG LE + C
Sbjct: 422 DDRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFC 475
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 454 bits (1169), Expect = e-128
Identities = 254/474 (53%), Positives = 311/474 (65%), Gaps = 2/474 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS + P RLLELAG+SLLRD+ALAIS L+ELP ELFP LF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F LPLGSLMK P E V+DG+D LL +VR RRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK +++DE + WV+ R VHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
CC K+ M N RNIL+TV D IQ +E+ N W ++AE + YL QM+NLRKL +
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
Query: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
SD S E + + V +F++ FL+L LQ LYM + F EG+LDQ++ CLK+ L LA
Sbjct: 240 SDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLA 299
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T L E DLK L YPS+ QLK L+LS L L PL+ LLEKVAATL+ L L DC
Sbjct: 300 LTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDC 359
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
GI S++ ILPALSRC LTTF F GN S L++LL HT RL+NL LE YPAPRES
Sbjct: 360 GIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 419
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473
D RG V L AELM +R +REP RI F CP CG LE + C
Sbjct: 420 DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 444 bits (1142), Expect = e-125
Identities = 247/464 (53%), Positives = 302/464 (65%), Gaps = 4/464 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS+++P RLLELAG+SLLR++ L I L+ELP E+FP +FMEA S RH EALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
FLRLPLGSLMK P ET QAVL GLD LL ++R RRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C P AM R+ V+D PR QPL VFIDLC K TLDE + L W+ R GLVHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CC K++ M + RN+LK V D IQE+E+ +L +F PYL QM NLRKL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 --DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNIL 298
D Y+S +Q +FV FL L Q LY+ +S ++ HL+ +L CLK L
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
Query: 299 AITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDD 358
+ L + D++ LS+YPS+ QLK L L + +L PL LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
Query: 359 CGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRES 418
C I DSQ+ +LPALSRC +LTTF FRGN ST L++LLCHT L+ L LELYPAP E
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
Query: 419 YDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
D RG V A + AELM +R +R+P+RI F CP CG+
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 444 bits (1142), Expect = e-125
Identities = 247/464 (53%), Positives = 302/464 (65%), Gaps = 4/464 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS+++P RLLELAG+SLLR++ L I L+ELP E+FP +FMEA S RH EALKLMVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
FLRLPLGSLMK P ET QAVL GLD LL ++R RRWKLQVLDL+DV NFW +WS A
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C P AM R+ V+D PR QPL VFIDLC K TLDE + L W+ R GLVHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CC K++ M + RN+LK V D IQE+E+ +L +F PYL QM NLRKL L+
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 --DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNIL 298
D Y+S +Q +FV FL L Q LY+ +S ++ HL+ +L CLK L
Sbjct: 241 FGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTF 298
Query: 299 AITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDD 358
+ L + D++ LS+YPS+ QLK L L + +L PL LLEKVAATLE L L D
Sbjct: 299 IFCHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKD 358
Query: 359 CGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRES 418
C I DSQ+ +LPALSRC +LTTF FRGN ST L++LLCHT L+ L LELYPAP E
Sbjct: 359 CQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLEC 418
Query: 419 YDVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
D RG V A + AELM +R +R+P+RI F CP CG+
Sbjct: 419 LDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGS 462
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 437 bits (1124), Expect = e-122
Identities = 251/489 (51%), Positives = 318/489 (65%), Gaps = 14/489 (2%)
Query: 1 MSIRTPPR-LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAW 59
MS+ T PR L+ELAG+SLL+DEALAI+ LE LP ELFPPLFM AF RH + LK MVQAW
Sbjct: 17 MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
Query: 60 PFLRLPLGSLMKRPCP--ETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVS-ENFWMVW 116
PF LPLG LMK ETF+AVLDGLD LL VR RRWKLQVLDL+ S ++FW VW
Sbjct: 77 PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
Query: 117 SEAMARRCL---PNAM--MNRKPVQDCPRMRGQQP---LTVFIDLCLKNRTLDEYFTCLF 168
S A P A M +K D +QP + V +DL LK DE F+ L
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
Query: 169 LWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYL 228
VK+++ ++ LCCKKLK+ M +I+ ILK V LD I+++EV C W LP LA+F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
Query: 229 GQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQM 287
GQM NLR+L+LS I S YISPE++++++ QFT+QFL L+CLQ LY++S+ FL G LDQ+
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
Query: 288 LSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKV 347
L + L L+ITNC L E D+ HLS+ PS+ QL L LSG L + S PLQ LLE+
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
Query: 348 AATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNL 407
+ATL+ L D+CGI D Q+ A+LP+LS C +LTT SF GN IS + L++LL H I L+NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
Query: 408 CLELYPAPRESY-DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLY 466
LYP P ESY D+ G + R A L A L + L P + + CP CG+R+ Y
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
Query: 467 DLEVDRCCC 475
D E C C
Sbjct: 497 DPEPILCPC 505
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 437 bits (1124), Expect = e-122
Identities = 251/489 (51%), Positives = 318/489 (65%), Gaps = 14/489 (2%)
Query: 1 MSIRTPPR-LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAW 59
MS+ T PR L+ELAG+SLL+DEALAI+ LE LP ELFPPLFM AF RH + LK MVQAW
Sbjct: 17 MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
Query: 60 PFLRLPLGSLMKRPCP--ETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVS-ENFWMVW 116
PF LPLG LMK ETF+AVLDGLD LL VR RRWKLQVLDL+ S ++FW VW
Sbjct: 77 PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
Query: 117 SEAMARRCL---PNAM--MNRKPVQDCPRMRGQQP---LTVFIDLCLKNRTLDEYFTCLF 168
S A P A M +K D +QP + V +DL LK DE F+ L
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
Query: 169 LWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYL 228
VK+++ ++ LCCKKLK+ M +I+ ILK V LD I+++EV C W LP LA+F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
Query: 229 GQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQM 287
GQM NLR+L+LS I S YISPE++++++ QFT+QFL L+CLQ LY++S+ FL G LDQ+
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
Query: 288 LSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKV 347
L + L L+ITNC L E D+ HLS+ PS+ QL L LSG L + S PLQ LLE+
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
Query: 348 AATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNL 407
+ATL+ L D+CGI D Q+ A+LP+LS C +LTT SF GN IS + L++LL H I L+NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
Query: 408 CLELYPAPRESY-DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLY 466
LYP P ESY D+ G + R A L A L + L P + + CP CG+R+ Y
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
Query: 467 DLEVDRCCC 475
D E C C
Sbjct: 497 DPEPILCPC 505
>gi|46249369 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 437 bits (1124), Expect = e-122
Identities = 251/489 (51%), Positives = 318/489 (65%), Gaps = 14/489 (2%)
Query: 1 MSIRTPPR-LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAW 59
MS+ T PR L+ELAG+SLL+DEALAI+ LE LP ELFPPLFM AF RH + LK MVQAW
Sbjct: 17 MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
Query: 60 PFLRLPLGSLMKRPCP--ETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVS-ENFWMVW 116
PF LPLG LMK ETF+AVLDGLD LL VR RRWKLQVLDL+ S ++FW VW
Sbjct: 77 PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
Query: 117 SEAMARRCL---PNAM--MNRKPVQDCPRMRGQQP---LTVFIDLCLKNRTLDEYFTCLF 168
S A P A M +K D +QP + V +DL LK DE F+ L
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
Query: 169 LWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYL 228
VK+++ ++ LCCKKLK+ M +I+ ILK V LD I+++EV C W LP LA+F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
Query: 229 GQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQM 287
GQM NLR+L+LS I S YISPE++++++ QFT+QFL L+CLQ LY++S+ FL G LDQ+
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
Query: 288 LSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKV 347
L + L L+ITNC L E D+ HLS+ PS+ QL L LSG L + S PLQ LLE+
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
Query: 348 AATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNL 407
+ATL+ L D+CGI D Q+ A+LP+LS C +LTT SF GN IS + L++LL H I L+NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
Query: 408 CLELYPAPRESY-DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLY 466
LYP P ESY D+ G + R A L A L + L P + + CP CG+R+ Y
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
Query: 467 DLEVDRCCC 475
D E C C
Sbjct: 497 DPEPILCPC 505
>gi|46249367 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 437 bits (1124), Expect = e-122
Identities = 251/489 (51%), Positives = 318/489 (65%), Gaps = 14/489 (2%)
Query: 1 MSIRTPPR-LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAW 59
MS+ T PR L+ELAG+SLL+DEALAI+ LE LP ELFPPLFM AF RH + LK MVQAW
Sbjct: 17 MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
Query: 60 PFLRLPLGSLMKRPCP--ETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVS-ENFWMVW 116
PF LPLG LMK ETF+AVLDGLD LL VR RRWKLQVLDL+ S ++FW VW
Sbjct: 77 PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
Query: 117 SEAMARRCL---PNAM--MNRKPVQDCPRMRGQQP---LTVFIDLCLKNRTLDEYFTCLF 168
S A P A M +K D +QP + V +DL LK DE F+ L
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
Query: 169 LWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYL 228
VK+++ ++ LCCKKLK+ M +I+ ILK V LD I+++EV C W LP LA+F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
Query: 229 GQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQM 287
GQM NLR+L+LS I S YISPE++++++ QFT+QFL L+CLQ LY++S+ FL G LDQ+
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
Query: 288 LSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKV 347
L + L L+ITNC L E D+ HLS+ PS+ QL L LSG L + S PLQ LLE+
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
Query: 348 AATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNL 407
+ATL+ L D+CGI D Q+ A+LP+LS C +LTT SF GN IS + L++LL H I L+NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
Query: 408 CLELYPAPRESY-DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLY 466
LYP P ESY D+ G + R A L A L + L P + + CP CG+R+ Y
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
Query: 467 DLEVDRCCC 475
D E C C
Sbjct: 497 DPEPILCPC 505
>gi|5174641 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 437 bits (1124), Expect = e-122
Identities = 251/489 (51%), Positives = 318/489 (65%), Gaps = 14/489 (2%)
Query: 1 MSIRTPPR-LLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAW 59
MS+ T PR L+ELAG+SLL+DEALAI+ LE LP ELFPPLFM AF RH + LK MVQAW
Sbjct: 17 MSVWTSPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAW 76
Query: 60 PFLRLPLGSLMKRPCP--ETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVS-ENFWMVW 116
PF LPLG LMK ETF+AVLDGLD LL VR RRWKLQVLDL+ S ++FW VW
Sbjct: 77 PFTCLPLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVW 136
Query: 117 SEAMARRCL---PNAM--MNRKPVQDCPRMRGQQP---LTVFIDLCLKNRTLDEYFTCLF 168
S A P A M +K D +QP + V +DL LK DE F+ L
Sbjct: 137 SGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLI 196
Query: 169 LWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYL 228
VK+++ ++ LCCKKLK+ M +I+ ILK V LD I+++EV C W LP LA+F+PYL
Sbjct: 197 EKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYL 256
Query: 229 GQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQM 287
GQM NLR+L+LS I S YISPE++++++ QFT+QFL L+CLQ LY++S+ FL G LDQ+
Sbjct: 257 GQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQL 316
Query: 288 LSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKV 347
L + L L+ITNC L E D+ HLS+ PS+ QL L LSG L + S PLQ LLE+
Sbjct: 317 LRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERA 376
Query: 348 AATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNL 407
+ATL+ L D+CGI D Q+ A+LP+LS C +LTT SF GN IS + L++LL H I L+NL
Sbjct: 377 SATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNL 436
Query: 408 CLELYPAPRESY-DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLY 466
LYP P ESY D+ G + R A L A L + L P + + CP CG+R+ Y
Sbjct: 437 THVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCGDRTFY 496
Query: 467 DLEVDRCCC 475
D E C C
Sbjct: 497 DPEPILCPC 505
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 429 bits (1103), Expect = e-120
Identities = 241/475 (50%), Positives = 305/475 (64%), Gaps = 2/475 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLFMEAF RRH + L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F LPLGSLMK ET +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C P M R+ +DCPRM QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
CC KL ++R LK + L+ IQ++E+ N +W ++ + YL +M+NLRKLV
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
Query: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
S E + VT+F++ FL+L LQ L + ++F GHL+Q++ CL+ L L
Sbjct: 240 SRCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T LLE D+K LS+YPS+G LK L+LS L SL PL LLEK+AA+LE L L+ C
Sbjct: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGC 359
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
I SQ++AILP LS C +LTTF F N +S L++LL HT L+ L LE YPAP ES
Sbjct: 360 QIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESL 419
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
+ V FA L AELM +R +R+P+RI CP CG+ +LE+ CC
Sbjct: 420 NSLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 426 bits (1095), Expect = e-119
Identities = 241/475 (50%), Positives = 304/475 (64%), Gaps = 2/475 (0%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MSI+ PPRLLELAG+SLLRD+AL+IS +EELP L+ PLFMEAFSRRH + L +MVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
F LPLGSLMK ET +A+L+GL LLT + R RRWKLQVLDL+DV ENFW W A
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
A C P R+ +DCPRM QPL VFID+CLK DE LF WV QR GLVHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
CC KL +R LK + L+ IQE+E+ N +W ++ + YL +M+NLRKLV
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWP-RLIRKLRCYLKEMKNLRKLVF 239
Query: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
S E + V +F++ FL+L LQ L + ++F GHL+Q++ CL+ L L
Sbjct: 240 SRCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLE 299
Query: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
+T LLE D+K LS+YPS+G LK L+LS L SL PL LLEK+AA+L+ L L+ C
Sbjct: 300 LTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGC 359
Query: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
I SQ++AILPALSRC +LTTF F N +S L++LL HT L+ L LE YPAP ES
Sbjct: 360 QIHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESL 419
Query: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRCC 474
+ V F L AELM +R +R+P+RI CP CG+ +LE+ CC
Sbjct: 420 NSLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLCC 474
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 424 bits (1091), Expect = e-119
Identities = 236/462 (51%), Positives = 296/462 (64%)
Query: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
MS++ P RLLELAG+SLLR++ L I TL+ELP E+FP +FMEAFS R EALKLMVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
FL LPLGSLMK ET QAVL GLD L+ +VR RRWKLQVLDL+DV ENFW +WS A
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
C P AM R+ V+DCPRM QPL VFIDLCLK TLDE + LF W+ R GLVHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCNWTLPVLAEFTPYLGQMRNLRKLVLS 240
CC K++ M + RN+L+ + D IQE+EV +L +F PYL QM NLR+L L+
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 DIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILAI 300
R + + + + FL L Q LY+ +S ++ HL+ +L LK L
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 301 TNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDCG 360
++ L + D++ LS+YPS+ QLK L L + L PL VLLEKVAATL+ L L DC
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 361 IVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESYD 420
I D Q+ +LPALS C +LTTF+F GN S L++LL HT L+ L LELYPAP ES D
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 421 VRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGN 462
+G V + AELM +R +R+P+RI F CP CG+
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGS 462
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.140 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,686,508
Number of Sequences: 37866
Number of extensions: 762275
Number of successful extensions: 2061
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 54
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1905
Number of HSP's gapped (non-prelim): 112
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.