Guide to the Human Genome
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Search of human proteins with 153791472

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo
sapiens]
         (795 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo ...  1587   0.0  
gi|254028234 MAP/microtubule affinity-regulating kinase 2 isofor...  1002   0.0  
gi|193083127 MAP/microtubule affinity-regulating kinase 3 isofor...   987   0.0  
gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform...   985   0.0  
gi|193083125 MAP/microtubule affinity-regulating kinase 3 isofor...   981   0.0  
gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform...   971   0.0  
gi|193083129 MAP/microtubule affinity-regulating kinase 3 isofor...   957   0.0  
gi|254028232 MAP/microtubule affinity-regulating kinase 2 isofor...   940   0.0  
gi|254028240 MAP/microtubule affinity-regulating kinase 2 isofor...   929   0.0  
gi|254028237 MAP/microtubule affinity-regulating kinase 2 isofor...   926   0.0  
gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo s...   693   0.0  
gi|193083131 MAP/microtubule affinity-regulating kinase 3 isofor...   522   e-148
gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]        379   e-105
gi|116256471 SNF1-like kinase [Homo sapiens]                          363   e-100
gi|38569460 SNF1-like kinase 2 [Homo sapiens]                         351   2e-96
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]               283   4e-76
gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]              278   1e-74
gi|156105707 SNF related kinase [Homo sapiens]                        270   5e-72
gi|156105705 SNF related kinase [Homo sapiens]                        270   5e-72
gi|46877068 AMP-activated protein kinase alpha 2 catalytic subun...   267   3e-71
gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic sub...   266   7e-71
gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic sub...   256   8e-68
gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]       255   1e-67
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]               252   8e-67
gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]           249   5e-66
gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]    244   2e-64
gi|7657214 hormonally upregulated Neu-associated kinase [Homo sa...   233   4e-61
gi|16418343 testis-specific serine kinase 3 [Homo sapiens]            195   2e-49
gi|14042947 testis-specific serine kinase 1 [Homo sapiens]            191   3e-48
gi|194294513 testis-specific serine kinase 2 [Homo sapiens]           182   8e-46

>gi|153791472 MAP/microtubule affinity-regulating kinase 1 [Homo
           sapiens]
          Length = 795

 Score = 1587 bits (4109), Expect = 0.0
 Identities = 795/795 (100%), Positives = 795/795 (100%)

Query: 1   MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY 60
           MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
Sbjct: 1   MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY 60

Query: 61  RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV 120
           RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV
Sbjct: 61  RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV 120

Query: 121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH 180
           KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
Sbjct: 121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH 180

Query: 181 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 240
           RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
Sbjct: 181 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 240

Query: 241 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG 300
           WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
Sbjct: 241 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG 300

Query: 301 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE 360
           SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
Sbjct: 301 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE 360

Query: 361 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR 420
           VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
Sbjct: 361 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR 420

Query: 421 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP 480
           RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
Sbjct: 421 RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP 480

Query: 481 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV 540
           ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
Sbjct: 481 ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV 540

Query: 541 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD 600
           ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD
Sbjct: 541 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD 600

Query: 601 RTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKF 660
           RTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKF
Sbjct: 601 RTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKF 660

Query: 661 VRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMRE 720
           VRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMRE
Sbjct: 661 VRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMRE 720

Query: 721 IRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSI 780
           IRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSI
Sbjct: 721 IRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSI 780

Query: 781 AFKNIASKIANELKL 795
           AFKNIASKIANELKL
Sbjct: 781 AFKNIASKIANELKL 795


>gi|254028234 MAP/microtubule affinity-regulating kinase 2 isoform d
           [Homo sapiens]
          Length = 788

 Score = 1002 bits (2591), Expect = 0.0
 Identities = 546/815 (66%), Positives = 636/815 (78%), Gaps = 50/815 (6%)

Query: 2   SARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNYR 61
           SARTPLPT+NERDTE  T   G+ +     +K SS+ N+ R RNS TSA DEQPHIGNYR
Sbjct: 3   SARTPLPTLNERDTEQPTL--GHLD-----SKPSSKSNMIRGRNSATSA-DEQPHIGNYR 54

Query: 62  LQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 121
           L KTIGKGNFAKVKLARH+LTG+EVAVKIIDKTQLN +SLQKLFREVRIMK+LNHPNIVK
Sbjct: 55  LLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVK 114

Query: 122 LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHR 181
           LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK+IVHR
Sbjct: 115 LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174

Query: 182 DLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 241
           DLKAENLLLD DMNIKIADFGFSNEFT GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW
Sbjct: 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 234

Query: 242 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGS 301
           SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK L+LNP KRG+
Sbjct: 235 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGT 294

Query: 302 LEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEV 361
           LEQIMKDRWMNVGHE++ELKPY EP PD+ D +R ++MV+MG+ R+EI D+L+ Q+Y+EV
Sbjct: 295 LEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEV 354

Query: 362 MATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRR 421
           MATY+LLG K  E EG        +  + RPS+DL NS+  SP+H KVQRS+SAN KQRR
Sbjct: 355 MATYLLLGYKSSELEG------DTITLKPRPSADLTNSSAPSPSH-KVQRSVSANPKQRR 407

Query: 422 FSDH-AGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP 480
           FSD  AGP+IP + SY+K+ Q+N+ E+++ EE D++  RK  ST     +++ ASPL G 
Sbjct: 408 FSDQAAGPAIPTSNSYSKKTQSNNAENKRPEE-DRESGRKASST-----AKVPASPLPGL 461

Query: 481 ERKKSSTIPS-NNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSS 539
           ERKK++  PS N+V S  +   RN+ + ER +    ++QNGKDS     S +S +SA   
Sbjct: 462 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASA--- 518

Query: 540 VASAVPSARPR-HQKSMSTSGHPIKVT-LPTIKDGSEAYRPGTT-QRVPAASPSAHSIST 596
            ++AV +ARPR HQKSMS S HP K + LP  +   E  RP T  QRVP ASPSAH+IS+
Sbjct: 519 -SAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISS 577

Query: 597 A--TPDRTRFPRGSSSRSTFHGEQL---RERRSVAYNGPPASPSHETGAFAHARRGTSTG 651
           +   PDRT FPRG SSRSTFH  QL   R+++++ Y   PASPS      +  RRG S  
Sbjct: 578 SGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS----GHSQGRRGASGS 633

Query: 652 IISKITSKFVRRDPS---------EGEASGRTDTSRS--TSGEPKERDKEEGKDSKPRSL 700
           I SK TSKFVRR+ S         E E+  R +T R         +++KEE +++KPRSL
Sbjct: 634 IFSKFTSKFVRRNLSFRFARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSL 693

Query: 701 RFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVC 760
           RFTWSMKTTSSM+PN+MMREIRKVLDAN+C  E  E+++L C+HG    +  VQWEMEVC
Sbjct: 694 RFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVC 753

Query: 761 KLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 795
           KLPRLSLNGVRFKRISGTS+AFKNIASKIANELKL
Sbjct: 754 KLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL 788


>gi|193083127 MAP/microtubule affinity-regulating kinase 3 isoform b
           [Homo sapiens]
          Length = 744

 Score =  987 bits (2551), Expect = 0.0
 Identities = 539/812 (66%), Positives = 604/812 (74%), Gaps = 85/812 (10%)

Query: 1   MSARTPLPTVNERDTENHTSV-DGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGN 59
           MS RTPLPTVNERDTENHTS  DG  E   + ++S +R     CRNSI S  DEQPHIGN
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGAR-----CRNSIASCADEQPHIGN 55

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
           YRL KTIGKGNFAKVKLARH+LTGREVA+KIIDKTQLNPTSLQKLFREVRIMKILNHPNI
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115

Query: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIV 179
           VKLFEVIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IV
Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175

Query: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVD 239
           HRDLKAENLLLD DMNIKIADFGFSNEFTVG KLDTFCGSPPYAAPELFQGKKYDGPEVD
Sbjct: 176 HRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVD 235

Query: 240 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKR 299
           VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+ LVLNPIKR
Sbjct: 236 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295

Query: 300 GSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYD 359
           G+LEQIMKDRW+N GHEE+ELKP+ EP+ D +D KRIDIMV MG++++EI ++L   KYD
Sbjct: 296 GTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYD 355

Query: 360 EVMATYILLGRKPPEFEGGESLSSGNL-CQRSRPSSDLNNSTLQSPAHLKVQRSISANQK 418
           E+ ATY+LLGRK  E +  +S SS NL   + RPSSDLNNST QSP H KVQRS+ ++QK
Sbjct: 356 EITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHH-KVQRSVFSSQK 414

Query: 419 QRRFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLV 478
           QRR+SDHAGP+IP  V+Y KR Q ++ +S+ KE  D   +RK   + VG K    ASP++
Sbjct: 415 QRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKE--DGISSRKSSGSAVGGKGIAPASPML 472

Query: 479 G----------PERKKSSTIPSNNVYSGGSMARRNTYVC-ERTT-DRYVALQNGKDSSLT 526
           G          PERKKSST+PS+N  SGG M RRNTYVC ERTT DR+  +QNGK++S  
Sbjct: 473 GNASNPNKADIPERKKSSTVPSSNTASGG-MTRRNTYVCSERTTADRHSVIQNGKENSTI 531

Query: 527 EMSVSSISSAGSSVASAVPS--ARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRV 584
               + ++S  S  ++A P     PR   S ST              G    R   T   
Sbjct: 532 PDQRTPVASTHSISSAATPDRIRFPRGTASRSTF------------HGQPRERRTATYNG 579

Query: 585 PAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHA 644
           P ASPS                                            SHE    +  
Sbjct: 580 PPASPSL-------------------------------------------SHEATPLSQT 596

Query: 645 RRGTSTGIISKITSKFVRRDPSEGEASGRTD-TSRSTSGEPKERDKEEGKDSKPRSLRFT 703
           R   ST + SK+TSK  RR P+E E +GR + +SR+ S E     K+E K++KPRSLRFT
Sbjct: 597 RSRGSTNLFSKLTSKLTRRLPTEYERNGRYEGSSRNVSAE----QKDENKEAKPRSLRFT 652

Query: 704 WSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLP 763
           WSMKTTSSMDP DMMREIRKVLDANNCDYEQ+ERFLLFCVHGD   ++LVQWEMEVCKLP
Sbjct: 653 WSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLP 712

Query: 764 RLSLNGVRFKRISGTSIAFKNIASKIANELKL 795
           RLSLNGVRFKRISGTSIAFKNIASKIANELKL
Sbjct: 713 RLSLNGVRFKRISGTSIAFKNIASKIANELKL 744


>gi|86990441 MAP/microtubule affinity-regulating kinase 2 isoform a
           [Homo sapiens]
          Length = 745

 Score =  985 bits (2546), Expect = 0.0
 Identities = 525/765 (68%), Positives = 610/765 (79%), Gaps = 33/765 (4%)

Query: 42  RCRNSITSATDEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSL 101
           R RNS TSA DEQPHIGNYRL KTIGKGNFAKVKLARH+LTG+EVAVKIIDKTQLN +SL
Sbjct: 3   RGRNSATSA-DEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSL 61

Query: 102 QKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 161
           QKLFREVRIMK+LNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA
Sbjct: 62  QKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARA 121

Query: 162 KFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPP 221
           KFRQIVSAVQYCHQK+IVHRDLKAENLLLD DMNIKIADFGFSNEFT GNKLDTFCGSPP
Sbjct: 122 KFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPP 181

Query: 222 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 281
           YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS
Sbjct: 182 YAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMS 241

Query: 282 TDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVT 341
           TDCENLLKK L+LNP KRG+LEQIMKDRWMNVGHE++ELKPY EP PD+ D +R ++MV+
Sbjct: 242 TDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVS 301

Query: 342 MGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTL 401
           MG+ R+EI D+L+ Q+Y+EVMATY+LLG K  E EG        +  + RPS+DL NS+ 
Sbjct: 302 MGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEG------DTITLKPRPSADLTNSSA 355

Query: 402 QSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKL 461
            SP+H KVQRS+SAN KQRRFSD AGP+IP + SY+K+ Q+N+ E+++ EE D++  RK 
Sbjct: 356 PSPSH-KVQRSVSANPKQRRFSDQAGPAIPTSNSYSKKTQSNNAENKRPEE-DRESGRKA 413

Query: 462 GSTTVGSKSEMTASPLVGPERKKSSTIPS-NNVYSGGSMARRNTYVCERTTDRYVALQNG 520
            ST     +++ ASPL G ERKK++  PS N+V S  +   RN+ + ER +    ++QNG
Sbjct: 414 SST-----AKVPASPLPGLERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNG 468

Query: 521 KDSSLTEMSVSSISSAGSSVASAVPSARPR-HQKSMSTSGHPIKVT-LPTIKDGSEAYRP 578
           KDS     S +S +SA    ++AV +ARPR HQKSMS S HP K + LP  +   E  RP
Sbjct: 469 KDSLTMPGSRASTASA----SAAVSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRP 524

Query: 579 GTT-QRVPAASPSAHSISTA--TPDRTRFPRGSSSRSTFHGEQL---RERRSVAYNGPPA 632
            T  QRVP ASPSAH+IS++   PDRT FPRG SSRSTFH  QL   R+++++ Y   PA
Sbjct: 525 STAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPA 584

Query: 633 SPSHETGAFAHARRGTSTGIISKITSKFVRRDPSEGEASGRTDTSRS--TSGEPKERDKE 690
           SPS      +  RRG S  I SK TSKFVRR+ +E E+  R +T R         +++KE
Sbjct: 585 SPS----GHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDRVETLRPHVVGSGGNDKEKE 640

Query: 691 EGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQD 750
           E +++KPRSLRFTWSMKTTSSM+PN+MMREIRKVLDAN+C  E  E+++L C+HG    +
Sbjct: 641 EFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHE 700

Query: 751 SLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 795
             VQWEMEVCKLPRLSLNGVRFKRISGTS+AFKNIASKIANELKL
Sbjct: 701 DFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL 745


>gi|193083125 MAP/microtubule affinity-regulating kinase 3 isoform a
           [Homo sapiens]
          Length = 753

 Score =  981 bits (2537), Expect = 0.0
 Identities = 539/821 (65%), Positives = 606/821 (73%), Gaps = 94/821 (11%)

Query: 1   MSARTPLPTVNERDTENHTSV-DGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGN 59
           MS RTPLPTVNERDTENHTS  DG  E   + ++S +R     CRNSI S  DEQPHIGN
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGAR-----CRNSIASCADEQPHIGN 55

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
           YRL KTIGKGNFAKVKLARH+LTGREVA+KIIDKTQLNPTSLQKLFREVRIMKILNHPNI
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115

Query: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIV 179
           VKLFEVIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IV
Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175

Query: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVD 239
           HRDLKAENLLLD DMNIKIADFGFSNEFTVG KLDTFCGSPPYAAPELFQGKKYDGPEVD
Sbjct: 176 HRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVD 235

Query: 240 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKR 299
           VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+ LVLNPIKR
Sbjct: 236 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295

Query: 300 GSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYD 359
           G+LEQIMKDRW+N GHEE+ELKP+ EP+ D +D KRIDIMV MG++++EI ++L   KYD
Sbjct: 296 GTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYD 355

Query: 360 EVMATYILLGRKPPEFEGGESLSSGNL-CQRSRPSSDLNNSTLQSPAHLKVQRSISANQK 418
           E+ ATY+LLGRK  E +  +S SS NL   + RPSSDLNNST QSP H KVQRS+ ++QK
Sbjct: 356 EITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHH-KVQRSVFSSQK 414

Query: 419 QRRFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLV 478
           QRR+SDHAGP+IP  V+Y KR Q ++ +S+ KE  D   +RK   + VG K    ASP++
Sbjct: 415 QRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKE--DGISSRKSSGSAVGGKGIAPASPML 472

Query: 479 G----------PERKKSSTIPSNNVYSGGSMARRNTYVC-ERTT-DRYVALQNGKDSSLT 526
           G          PERKKSST+PS+N  SGG M RRNTYVC ERTT DR+  +QNGK++S  
Sbjct: 473 GNASNPNKADIPERKKSSTVPSSNTASGG-MTRRNTYVCSERTTADRHSVIQNGKENSTI 531

Query: 527 EMSVSSISSAGSSVASAVPS--ARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRV 584
               + ++S  S  ++A P     PR   S ST              G    R   T   
Sbjct: 532 PDQRTPVASTHSISSAATPDRIRFPRGTASRSTF------------HGQPRERRTATYNG 579

Query: 585 PAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHA 644
           P ASPS                                            SHE    +  
Sbjct: 580 PPASPSL-------------------------------------------SHEATPLSQT 596

Query: 645 RRGTSTGIISKITSK---------FVRRDPSEGEASGRTD-TSRSTSGEPKERDKEEGKD 694
           R   ST + SK+TSK         F++R P+E E +GR + +SR+ S E     K+E K+
Sbjct: 597 RSRGSTNLFSKLTSKLTRRNMSFRFIKRLPTEYERNGRYEGSSRNVSAE----QKDENKE 652

Query: 695 SKPRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQ 754
           +KPRSLRFTWSMKTTSSMDP DMMREIRKVLDANNCDYEQ+ERFLLFCVHGD   ++LVQ
Sbjct: 653 AKPRSLRFTWSMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQ 712

Query: 755 WEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 795
           WEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL
Sbjct: 713 WEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 753


>gi|46852166 MAP/microtubule affinity-regulating kinase 3 isoform c
           [Homo sapiens]
          Length = 729

 Score =  971 bits (2510), Expect = 0.0
 Identities = 533/811 (65%), Positives = 594/811 (73%), Gaps = 98/811 (12%)

Query: 1   MSARTPLPTVNERDTENHTSV-DGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGN 59
           MS RTPLPTVNERDTENHTS  DG  E   + ++S +R     CRNSI S  DEQPHIGN
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGAR-----CRNSIASCADEQPHIGN 55

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
           YRL KTIGKGNFAKVKLARH+LTGREVA+KIIDKTQLNPTSLQKLFREVRIMKILNHPNI
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115

Query: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIV 179
           VKLFEVIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IV
Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175

Query: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVD 239
           HRDLKAENLLLD DMNIKIADFGFSNEFTVG KLDTFCGSPPYAAPELFQGKKYDGPEVD
Sbjct: 176 HRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVD 235

Query: 240 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKR 299
           VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+ LVLNPIKR
Sbjct: 236 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295

Query: 300 GSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYD 359
           G+LEQIMKDRW+N GHEE+ELKP+ EP+ D +D KRIDIMV MG++++EI ++L   KYD
Sbjct: 296 GTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYD 355

Query: 360 EVMATYILLGRKPPEFEGGESLSSGNL-CQRSRPSSDLNNSTLQSPAHLKVQRSISANQK 418
           E+ ATY+LLGRK  E +  +S SS NL   + RPSSDLNNST QSP H KVQRS+ ++QK
Sbjct: 356 EITATYLLLGRKSSELDASDSSSSSNLSLAKVRPSSDLNNSTGQSPHH-KVQRSVFSSQK 414

Query: 419 QRRFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLV 478
           QRR+SDHAGP+IP  V+Y KR Q ++ +S+ KE  D   +RK   + VG K    ASP++
Sbjct: 415 QRRYSDHAGPAIPSVVAYPKRSQTSTADSDLKE--DGISSRKSSGSAVGGKGIAPASPML 472

Query: 479 G----------PERKKSSTIPSNNVYSGGSMARRNTYVC-ERTT-DRYVALQNGKDSSLT 526
           G          PERKKSST+PS+N  SGG M RRNTYVC ERTT DR+  +QNGK++S  
Sbjct: 473 GNASNPNKADIPERKKSSTVPSSNTASGG-MTRRNTYVCSERTTADRHSVIQNGKENSTI 531

Query: 527 EMSVSSISSAGSSVASAVPS--ARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRV 584
               + ++S  S  ++A P     PR   S ST              G    R   T   
Sbjct: 532 PDQRTPVASTHSISSAATPDRIRFPRGTASRSTF------------HGQPRERRTATYNG 579

Query: 585 PAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHA 644
           P ASPS                                            SHE    +  
Sbjct: 580 PPASPSL-------------------------------------------SHEATPLSQT 596

Query: 645 RRGTSTGIISKITSKFVRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTW 704
           R   ST + SK+TSK  R              SR+ S E     K+E K++KPRSLRFTW
Sbjct: 597 RSRGSTNLFSKLTSKLTR--------------SRNVSAE----QKDENKEAKPRSLRFTW 638

Query: 705 SMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPR 764
           SMKTTSSMDP DMMREIRKVLDANNCDYEQ+ERFLLFCVHGD   ++LVQWEMEVCKLPR
Sbjct: 639 SMKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPR 698

Query: 765 LSLNGVRFKRISGTSIAFKNIASKIANELKL 795
           LSLNGVRFKRISGTSIAFKNIASKIANELKL
Sbjct: 699 LSLNGVRFKRISGTSIAFKNIASKIANELKL 729


>gi|193083129 MAP/microtubule affinity-regulating kinase 3 isoform d
           [Homo sapiens]
          Length = 713

 Score =  957 bits (2473), Expect = 0.0
 Identities = 528/810 (65%), Positives = 586/810 (72%), Gaps = 112/810 (13%)

Query: 1   MSARTPLPTVNERDTENHTSV-DGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGN 59
           MS RTPLPTVNERDTENHTS  DG  E   + ++S +R     CRNSI S  DEQPHIGN
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGAR-----CRNSIASCADEQPHIGN 55

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
           YRL KTIGKGNFAKVKLARH+LTGREVA+KIIDKTQLNPTSLQKLFREVRIMKILNHPNI
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115

Query: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIV 179
           VKLFEVIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IV
Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175

Query: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVD 239
           HRDLKAENLLLD DMNIKIADFGFSNEFTVG KLDTFCGSPPYAAPELFQGKKYDGPEVD
Sbjct: 176 HRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDTFCGSPPYAAPELFQGKKYDGPEVD 235

Query: 240 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKR 299
           VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLK+ LVLNPIKR
Sbjct: 236 VWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKR 295

Query: 300 GSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYD 359
           G+LEQIMKDRW+N GHEE+ELKP+ EP+ D +D KRIDIMV MG++++EI ++L   KYD
Sbjct: 296 GTLEQIMKDRWINAGHEEDELKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYD 355

Query: 360 EVMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQ 419
           E+ ATY+LLGRK  E                RPSSDLNNST QSP H KVQRS+ ++QKQ
Sbjct: 356 EITATYLLLGRKSSEV---------------RPSSDLNNSTGQSPHH-KVQRSVFSSQKQ 399

Query: 420 RRFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVG 479
           RR+SDHAGP+IP  V+Y KR Q ++ +S+ KE  D   +RK   + VG K    ASP++G
Sbjct: 400 RRYSDHAGPAIPSVVAYPKRSQTSTADSDLKE--DGISSRKSSGSAVGGKGIAPASPMLG 457

Query: 480 ----------PERKKSSTIPSNNVYSGGSMARRNTYVC-ERTT-DRYVALQNGKDSSLTE 527
                     PERKKSST+PS+N  SGG M RRNTYVC ERTT DR+  +QNGK++S   
Sbjct: 458 NASNPNKADIPERKKSSTVPSSNTASGG-MTRRNTYVCSERTTADRHSVIQNGKENSTIP 516

Query: 528 MSVSSISSAGSSVASAVPS--ARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVP 585
              + ++S  S  ++A P     PR   S ST              G    R   T   P
Sbjct: 517 DQRTPVASTHSISSAATPDRIRFPRGTASRSTF------------HGQPRERRTATYNGP 564

Query: 586 AASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHAR 645
            ASPS                                            SHE    +  R
Sbjct: 565 PASPSL-------------------------------------------SHEATPLSQTR 581

Query: 646 RGTSTGIISKITSKFVRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWS 705
              ST + SK+TSK  R              SR+ S E     K+E K++KPRSLRFTWS
Sbjct: 582 SRGSTNLFSKLTSKLTR--------------SRNVSAE----QKDENKEAKPRSLRFTWS 623

Query: 706 MKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRL 765
           MKTTSSMDP DMMREIRKVLDANNCDYEQ+ERFLLFCVHGD   ++LVQWEMEVCKLPRL
Sbjct: 624 MKTTSSMDPGDMMREIRKVLDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRL 683

Query: 766 SLNGVRFKRISGTSIAFKNIASKIANELKL 795
           SLNGVRFKRISGTSIAFKNIASKIANELKL
Sbjct: 684 SLNGVRFKRISGTSIAFKNIASKIANELKL 713


>gi|254028232 MAP/microtubule affinity-regulating kinase 2 isoform c
           [Homo sapiens]
          Length = 724

 Score =  940 bits (2430), Expect = 0.0
 Identities = 509/800 (63%), Positives = 594/800 (74%), Gaps = 84/800 (10%)

Query: 2   SARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNYR 61
           SARTPLPT+NERDTE  T   G+ +     +K SS+ N+ R RNS TSA DEQPHIGNYR
Sbjct: 3   SARTPLPTLNERDTEQPTL--GHLD-----SKPSSKSNMIRGRNSATSA-DEQPHIGNYR 54

Query: 62  LQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 121
           L KTIGKGNFAKVKLARH+LTG+EVAVKIIDKTQLN +SLQKLFREVRIMK+LNHPNIVK
Sbjct: 55  LLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVK 114

Query: 122 LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHR 181
           LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK+IVHR
Sbjct: 115 LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174

Query: 182 DLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 241
           DLKAENLLLD DMNIKIADFGFSNEFT GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW
Sbjct: 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 234

Query: 242 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGS 301
           SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK L+LNP KRG+
Sbjct: 235 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGT 294

Query: 302 LEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEV 361
           LEQIMKDRWMNVGHE++ELKPY EP PD+ D +R ++MV+MG+ R+EI D+L+ Q+Y+EV
Sbjct: 295 LEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEV 354

Query: 362 MATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRR 421
           MATY+LLG K  E EG        +  + RPS+DL NS+  SP+H KVQRS+SAN KQRR
Sbjct: 355 MATYLLLGYKSSELEG------DTITLKPRPSADLTNSSAPSPSH-KVQRSVSANPKQRR 407

Query: 422 FSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPE 481
           FSD AGP+IP + SY+K+ Q+N+ E+++ EE D++  RK  ST     +++ ASPL G E
Sbjct: 408 FSDQAGPAIPTSNSYSKKTQSNNAENKRPEE-DRESGRKASST-----AKVPASPLPGLE 461

Query: 482 RKKSSTIPS-NNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV 540
           RKK++  PS N+V S  +   RN+ + ER +    ++QNGKDS+  +             
Sbjct: 462 RKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSTAPQ------------- 508

Query: 541 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD 600
              VP A P      S+ G P +   P                                 
Sbjct: 509 --RVPVASPSAHNISSSGGAPDRTNFP--------------------------------- 533

Query: 601 RTRFPRGSSSRSTFHGEQL---RERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKIT 657
                RG SSRSTFH  QL   R+++++ Y   PASPS      +  RRG S  I SK T
Sbjct: 534 -----RGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS----GHSQGRRGASGSIFSKFT 584

Query: 658 SKFVRRDPSEGEASGRTDTSRS--TSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPN 715
           SKFVRR+ +E E+  R +T R         +++KEE +++KPRSLRFTWSMKTTSSM+PN
Sbjct: 585 SKFVRRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPN 644

Query: 716 DMMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRI 775
           +MMREIRKVLDAN+C  E  E+++L C+HG    +  VQWEMEVCKLPRLSLNGVRFKRI
Sbjct: 645 EMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRI 704

Query: 776 SGTSIAFKNIASKIANELKL 795
           SGTS+AFKNIASKIANELKL
Sbjct: 705 SGTSMAFKNIASKIANELKL 724


>gi|254028240 MAP/microtubule affinity-regulating kinase 2 isoform f
           [Homo sapiens]
          Length = 709

 Score =  929 bits (2402), Expect = 0.0
 Identities = 508/798 (63%), Positives = 588/798 (73%), Gaps = 95/798 (11%)

Query: 2   SARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNYR 61
           SARTPLPT+NERDTE  T   G+ +     +K SS+ N+ R RNS TSA DEQPHIGNYR
Sbjct: 3   SARTPLPTLNERDTEQPTL--GHLD-----SKPSSKSNMIRGRNSATSA-DEQPHIGNYR 54

Query: 62  LQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 121
           L KTIGKGNFAKVKLARH+LTG+EVAVKIIDKTQLN +SLQKLFREVRIMK+LNHPNIVK
Sbjct: 55  LLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVK 114

Query: 122 LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHR 181
           LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK+IVHR
Sbjct: 115 LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174

Query: 182 DLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 241
           DLKAENLLLD DMNIKIADFGFSNEFT GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW
Sbjct: 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 234

Query: 242 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGS 301
           SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK L+LNP KRG+
Sbjct: 235 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGT 294

Query: 302 LEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEV 361
           LEQIMKDRWMNVGHE++ELKPY EP PD+ D +R ++MV+MG+ R+EI D+L+ Q+Y+EV
Sbjct: 295 LEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEV 354

Query: 362 MATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRR 421
           MATY+LLG K  E EG        +  + RPS+DL NS+  SP+H KVQRS+SAN KQRR
Sbjct: 355 MATYLLLGYKSSELEG------DTITLKPRPSADLTNSSAPSPSH-KVQRSVSANPKQRR 407

Query: 422 FSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGPE 481
           FSD AGP+IP + SY+K+ Q+N+ E+++ EE D++  RK  ST     +++ ASPL G E
Sbjct: 408 FSDQAGPAIPTSNSYSKKTQSNNAENKRPEE-DRESGRKASST-----AKVPASPLPGLE 461

Query: 482 RKKSSTIPS-NNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV 540
           RKK++  PS N+V S  +   RN+ + ER +    ++QNGKDS+  +             
Sbjct: 462 RKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSTAPQ------------- 508

Query: 541 ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD 600
              VP A P      S+ G P +   P                                 
Sbjct: 509 --RVPVASPSAHNISSSGGAPDRTNFP--------------------------------- 533

Query: 601 RTRFPRGSSSRSTFHGEQL---RERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKIT 657
                RG SSRSTFH  QL   R+++++ Y   PASPS      +  RRG S  I SK T
Sbjct: 534 -----RGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS----GHSQGRRGASGSIFSKFT 584

Query: 658 SKFVRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDM 717
           SKFVRR    G  SG  D           ++KEE +++KPRSLRFTWSMKTTSSM+PN+M
Sbjct: 585 SKFVRRPHVVG--SGGND-----------KEKEEFREAKPRSLRFTWSMKTTSSMEPNEM 631

Query: 718 MREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISG 777
           MREIRKVLDAN+C  E  E+++L C+HG    +  VQWEMEVCKLPRLSLNGVRFKRISG
Sbjct: 632 MREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISG 691

Query: 778 TSIAFKNIASKIANELKL 795
           TS+AFKNIASKIANELKL
Sbjct: 692 TSMAFKNIASKIANELKL 709


>gi|254028237 MAP/microtubule affinity-regulating kinase 2 isoform e
           [Homo sapiens]
          Length = 719

 Score =  926 bits (2392), Expect = 0.0
 Identities = 510/799 (63%), Positives = 590/799 (73%), Gaps = 87/799 (10%)

Query: 2   SARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNYR 61
           SARTPLPT+NERDTE  T   G+ +     +K SS+ N+ R RNS TSA DEQPHIGNYR
Sbjct: 3   SARTPLPTLNERDTEQPTL--GHLD-----SKPSSKSNMIRGRNSATSA-DEQPHIGNYR 54

Query: 62  LQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIVK 121
           L KTIGKGNFAKVKLARH+LTG+EVAVKIIDKTQLN +SLQKLFREVRIMK+LNHPNIVK
Sbjct: 55  LLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVK 114

Query: 122 LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHR 181
           LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK+IVHR
Sbjct: 115 LFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHR 174

Query: 182 DLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 241
           DLKAENLLLD DMNIKIADFGFSNEFT GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW
Sbjct: 175 DLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVW 234

Query: 242 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGS 301
           SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK L+LNP KRG+
Sbjct: 235 SLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGT 294

Query: 302 LEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEV 361
           LEQIMKDRWMNVGHE++ELKPY EP PD+ D +R ++MV+MG+ R+EI D+L+ Q+Y+EV
Sbjct: 295 LEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEV 354

Query: 362 MATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRR 421
           MATY+LLG K  E EG        +  + RPS+DL NS+  SP+H KVQRS+SAN KQRR
Sbjct: 355 MATYLLLGYKSSELEG------DTITLKPRPSADLTNSSAPSPSH-KVQRSVSANPKQRR 407

Query: 422 FSDH-AGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP 480
           FSD  AGP+IP + SY+K+ Q+N+ E+++ EE D++  RK  ST     +++ ASPL G 
Sbjct: 408 FSDQAAGPAIPTSNSYSKKTQSNNAENKRPEE-DRESGRKASST-----AKVPASPLPGL 461

Query: 481 ERKKSSTIPS-NNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSS 539
           ERKK++  PS N+V S  +   RN+ + ER +    ++QNGKDS+  +            
Sbjct: 462 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSTAPQ------------ 509

Query: 540 VASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATP 599
               VP A P      S+ G P +   P                                
Sbjct: 510 ---RVPVASPSAHNISSSGGAPDRTNFP-------------------------------- 534

Query: 600 DRTRFPRGSSSRSTFHGEQL---RERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKI 656
                 RG SSRSTFH  QL   R+++++ Y   PASPS      +  RRG S  I SK 
Sbjct: 535 ------RGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPS----GHSQGRRGASGSIFSKF 584

Query: 657 TSKFVRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPND 716
           TSKFVRR+ S   A  R      + G  KE  KEE +++KPRSLRFTWSMKTTSSM+PN+
Sbjct: 585 TSKFVRRNLSFRFA--RRPHVVGSGGNDKE--KEEFREAKPRSLRFTWSMKTTSSMEPNE 640

Query: 717 MMREIRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRIS 776
           MMREIRKVLDAN+C  E  E+++L C+HG    +  VQWEMEVCKLPRLSLNGVRFKRIS
Sbjct: 641 MMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRIS 700

Query: 777 GTSIAFKNIASKIANELKL 795
           GTS+AFKNIASKIANELKL
Sbjct: 701 GTSMAFKNIASKIANELKL 719


>gi|33636756 MAP/microtubule affinity-regulating kinase 4 [Homo
           sapiens]
          Length = 688

 Score =  693 bits (1788), Expect = 0.0
 Identities = 405/723 (56%), Positives = 480/723 (66%), Gaps = 90/723 (12%)

Query: 1   MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY 60
           MS+RT L   N+R+++ H ++         P+ SS R    RCRNSI S  +EQPH+GNY
Sbjct: 1   MSSRTVLAPGNDRNSDTHGTLGSGRSSDKGPSWSS-RSLGARCRNSIASCPEEQPHVGNY 59

Query: 61  RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV 120
           RL +TIGKGNFAKVKLARH+LTGREVA+KIIDKTQLNP+SLQKLFREVRIMK LNHPNIV
Sbjct: 60  RLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIV 119

Query: 121 KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH 180
           KLFEVIETEKTLYLVMEYAS GEVFDYLV+HGRMKEKEARAKFRQIVSAV YCHQK IVH
Sbjct: 120 KLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVH 179

Query: 181 RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV 240
           RDLKAENLLLD + NIKIADFGFSNEFT+G+KLDTFCGSPPYAAPELFQGKKYDGPEVD+
Sbjct: 180 RDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDI 239

Query: 241 WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG 300
           WSLGVILYTLVSGSLPFDG NLKELRERVLRGKYR+PFYMSTDCE++L++ LVLNP KR 
Sbjct: 240 WSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRC 299

Query: 301 SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE 360
           +LEQIMKD+W+N+G+E EELKPYTEP+ DF DTKRI++MV MG+ R+EI ++L +QKY+E
Sbjct: 300 TLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNE 359

Query: 361 VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQS--PAHLKVQRSISAN-Q 417
           V ATY+LLGRK    EGG+  + G    R R  SD  N T  S   +H K QRS S+   
Sbjct: 360 VTATYLLLGRKTE--EGGDRGAPGLALARVRAPSDTTNGTSSSKGTSHSKGQRSSSSTYH 417

Query: 418 KQRRFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSE--MTAS 475
           +QRR SD  GPS  PA  + KR   ++ E+E KEE  +   RK   +T GS S     +S
Sbjct: 418 RQRRHSDFCGPS--PAPLHPKRSPTSTGEAELKEE--RLPGRKASCSTAGSGSRGLPPSS 473

Query: 476 PLVG----------PERKKSSTIPSNNVYSGGSMARRNTYVCERT--TDRYVALQNGKDS 523
           P+V           PER+K ST   NN+     M RRNTYVC      +R   L NGK++
Sbjct: 474 PMVSSAHNPNKAEIPERRKDSTSTPNNL-PPSMMTRRNTYVCTERPGAERPSLLPNGKEN 532

Query: 524 SLTEMSVSSISSAGSSVASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQR 583
                         SS    VP A P        S H +                     
Sbjct: 533 --------------SSGTPRVPPASP--------SSHSL--------------------- 549

Query: 584 VPAASPSAHSISTATPDRTRFPRGSSSRSTFHGEQLRERRS------VAYNGPPASP--S 635
              A PS         +R+R  RGS+ RSTFHG Q+R+RR+         NGPPASP  +
Sbjct: 550 ---APPSG--------ERSRLARGSTIRSTFHGGQVRDRRAGGGGGGGVQNGPPASPTLA 598

Query: 636 HETGAFAHARRGTSTGIISKITSKFVRR---DPSEGEASGRTDTSRSTSGEPKERDKEEG 692
           HE       R   +T + +K+TSK  RR   DPS+ + S R  +  S     K R +   
Sbjct: 599 HEAAPLPAGRPRPTTNLFTKLTSKLTRRVTLDPSKRQNSNRCVSGASLPQGSKIRSQTNL 658

Query: 693 KDS 695
           ++S
Sbjct: 659 RES 661


>gi|193083131 MAP/microtubule affinity-regulating kinase 3 isoform e
           [Homo sapiens]
          Length = 659

 Score =  522 bits (1345), Expect = e-148
 Identities = 304/551 (55%), Positives = 360/551 (65%), Gaps = 83/551 (15%)

Query: 260 QNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEE 319
           ++LKELRERVLRGKYRIPFYMSTDCENLLK+ LVLNPIKRG+LEQIMKDRW+N GHEE+E
Sbjct: 177 RDLKELRERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDE 236

Query: 320 LKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGE 379
           LKP+ EP+ D +D KRIDIMV MG++++EI ++L   KYDE+ ATY+LLGRK  E +  +
Sbjct: 237 LKPFVEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASD 296

Query: 380 SLSSGNL-CQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGPSIPPAVSYTK 438
           S SS NL   + RPSSDLNNST QSP H KVQRS+ ++QKQRR+SDHAGP+IP  V+Y K
Sbjct: 297 SSSSSNLSLAKVRPSSDLNNSTGQSPHH-KVQRSVFSSQKQRRYSDHAGPAIPSVVAYPK 355

Query: 439 RPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVG----------PERKKSSTI 488
           R Q ++ +S+ KE  D   +RK   + VG K    ASP++G          PERKKSST+
Sbjct: 356 RSQTSTADSDLKE--DGISSRKSSGSAVGGKGIAPASPMLGNASNPNKADIPERKKSSTV 413

Query: 489 PSNNVYSGGSMARRNTYVC-ERTT-DRYVALQNGKDSSLTEMSVSSISSAGSSVASAVPS 546
           PS+N  SGG M RRNTYVC ERTT DR+  +QNGK++S      + ++S  S  ++A P 
Sbjct: 414 PSSNTASGG-MTRRNTYVCSERTTADRHSVIQNGKENSTIPDQRTPVASTHSISSAATPD 472

Query: 547 --ARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPDRTRF 604
               PR   S ST              G    R   T   P ASPS              
Sbjct: 473 RIRFPRGTASRSTF------------HGQPRERRTATYNGPPASPSL------------- 507

Query: 605 PRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKFVRRD 664
                                         SHE    +  R   ST + SK+TSK  RR+
Sbjct: 508 ------------------------------SHEATPLSQTRSRGSTNLFSKLTSKLTRRN 537

Query: 665 PSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMREIRKV 724
                 S R   SR+ S E     K+E K++KPRSLRFTWSMKTTSSMDP DMMREIRKV
Sbjct: 538 -----MSFRFIKSRNVSAE----QKDENKEAKPRSLRFTWSMKTTSSMDPGDMMREIRKV 588

Query: 725 LDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKN 784
           LDANNCDYEQ+ERFLLFCVHGD   ++LVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKN
Sbjct: 589 LDANNCDYEQRERFLLFCVHGDGHAENLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKN 648

Query: 785 IASKIANELKL 795
           IASKIANELKL
Sbjct: 649 IASKIANELKL 659



 Score =  305 bits (781), Expect = 1e-82
 Identities = 157/185 (84%), Positives = 165/185 (89%), Gaps = 6/185 (3%)

Query: 1   MSARTPLPTVNERDTENHTSV-DGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGN 59
           MS RTPLPTVNERDTENHTS  DG  E   + ++S +R     CRNSI S  DEQPHIGN
Sbjct: 1   MSTRTPLPTVNERDTENHTSHGDGRQEVTSRTSRSGAR-----CRNSIASCADEQPHIGN 55

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
           YRL KTIGKGNFAKVKLARH+LTGREVA+KIIDKTQLNPTSLQKLFREVRIMKILNHPNI
Sbjct: 56  YRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 115

Query: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIV 179
           VKLFEVIETEKTLYL+MEYASGGEVFDYLVAHGRMKEKEAR+KFRQIVSAVQYCHQK IV
Sbjct: 116 VKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMKEKEARSKFRQIVSAVQYCHQKRIV 175

Query: 180 HRDLK 184
           HRDLK
Sbjct: 176 HRDLK 180


>gi|38569491 serine/threonine-protein kinase QSK [Homo sapiens]
          Length = 1263

 Score =  379 bits (973), Expect = e-105
 Identities = 190/322 (59%), Positives = 246/322 (76%), Gaps = 12/322 (3%)

Query: 57  IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNH 116
           IG Y + +TIGKGNFA VK A H++T  +VA+KIIDKTQL+  +L+K+FREV+IMK+L H
Sbjct: 5   IGYYEIDRTIGKGNFAVVKRATHLVTKAKVAIKIIDKTQLDEENLKKIFREVQIMKMLCH 64

Query: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176
           P+I++L++V+ETE+ +YLV EYASGGE+FD+LVAHGRM EKEAR KF+QIV+AV +CH +
Sbjct: 65  PHIIRLYQVMETERMIYLVTEYASGGEIFDHLVAHGRMAEKEARRKFKQIVTAVYFCHCR 124

Query: 177 YIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGP 236
            IVHRDLKAENLLLD ++NIKIADFGFSN FT G  L T+CGSPPYAAPELF+GK+YDGP
Sbjct: 125 NIVHRDLKAENLLLDANLNIKIADFGFSNLFTPGQLLKTWCGSPPYAAPELFEGKEYDGP 184

Query: 237 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNP 296
           +VD+WSLGV+LY LV G+LPFDG  L+ LR RVL GK+RIPF+MST+CE+L++ +LVL+P
Sbjct: 185 KVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSGKFRIPFFMSTECEHLIRHMLVLDP 244

Query: 297 IKRGSLEQIMKDRWMNVGH----------EEEELKPYTEPDPDFNDTKRIDIMVTMGFAR 346
            KR S+EQI K +WM +G           E ++LK   + DP   D   +  M  MG  +
Sbjct: 245 NKRLSMEQICKHKWMKLGDADPNFDRLIAECQQLKEERQVDPLNEDV--LLAMEDMGLDK 302

Query: 347 DEINDALINQKYDEVMATYILL 368
           ++   +L +  YD   A Y LL
Sbjct: 303 EQTLQSLRSDAYDHYSAIYSLL 324


>gi|116256471 SNF1-like kinase [Homo sapiens]
          Length = 783

 Score =  363 bits (931), Expect = e-100
 Identities = 177/348 (50%), Positives = 249/348 (71%), Gaps = 8/348 (2%)

Query: 57  IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNH 116
           +G Y +++T+GKGNFA VKLARH +T  +VA+KIIDKT+L+ ++L+K++REV++MK+LNH
Sbjct: 24  VGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNH 83

Query: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176
           P+I+KL++V+ET+  LY+V E+A  GE+FDYL ++G + E EAR KF QI+SAV+YCH  
Sbjct: 84  PHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDH 143

Query: 177 YIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGP 236
           +IVHRDLK ENLLLDG+M+IK+ADFGF N +  G  L T+CGSPPYAAPE+F+GK+Y+GP
Sbjct: 144 HIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGP 203

Query: 237 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNP 296
           ++D+WSLGV+LY LV GSLPFDG NL  LR+RVL G++RIPF+MS DCE+L++++LV++P
Sbjct: 204 QLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDP 263

Query: 297 IKRGSLEQIMKDRWMNV-------GHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEI 349
            +R ++ QI + RWM                  YT    D+ D + + IM T+G  R   
Sbjct: 264 ARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDY-DEQALGIMQTLGVDRQRT 322

Query: 350 NDALINQKYDEVMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLN 397
            ++L N  Y+   A Y LL  +  E+   +    G   Q    SSDL+
Sbjct: 323 VESLQNSSYNHFAAIYYLLLERLKEYRNAQCARPGPARQPRPRSSDLS 370


>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
          Length = 926

 Score =  351 bits (900), Expect = 2e-96
 Identities = 170/319 (53%), Positives = 237/319 (74%), Gaps = 9/319 (2%)

Query: 57  IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNH 116
           +G Y ++ T+GKGNFA VKL RH +T  EVA+KIIDK+QL+  +L+K++REV+IMK+L+H
Sbjct: 17  VGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDH 76

Query: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176
           P+I+KL++V+ET+  LYLV EYA  GE+FDYL  HGR+ E EAR KF QI+SAV YCH +
Sbjct: 77  PHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGR 136

Query: 177 YIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGP 236
            IVHRDLKAENLLLD +MNIKIADFGF N F  G  L T+CGSPPYAAPE+F+G++Y+GP
Sbjct: 137 KIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGP 196

Query: 237 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNP 296
           ++D+WS+GV+LY LV G+LPFDG  L  LR+RVL G++RIP++MS DCE+L++++LVL+P
Sbjct: 197 QLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDP 256

Query: 297 IKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFND-------TKRIDIMVTMGFARDEI 349
            KR ++ QI + +WM +  E    +P   P    N+        + + +M ++G  + + 
Sbjct: 257 SKRLTIAQIKEHKWMLI--EVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKT 314

Query: 350 NDALINQKYDEVMATYILL 368
            ++L N+ Y+   A Y LL
Sbjct: 315 IESLQNKSYNHFAAIYFLL 333


>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
          Length = 778

 Score =  283 bits (724), Expect = 4e-76
 Identities = 149/331 (45%), Positives = 213/331 (64%), Gaps = 17/331 (5%)

Query: 56  HIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILN 115
           ++G YRL+KT+GKG    VKL  H +TG++VA+KI+++ +L+ + L K+ RE+ I+K++ 
Sbjct: 30  YVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVEREIAILKLIE 89

Query: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 175
           HP+++KL +V E +K LYLV+E+ SGGE+FDYLV  GR+  KEAR  FRQIVSA+ +CH 
Sbjct: 90  HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHS 149

Query: 176 KYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235
             I HRDLK ENLLLD   NI+IADFG ++     + L+T CGSP YA PE+ +G+KYDG
Sbjct: 150 YSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDG 209

Query: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLN 295
              D+WS GVIL+ L+ G+LPFD  NL++L E+V RG + +P ++  DC++LL+ ++ + 
Sbjct: 210 RRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVE 269

Query: 296 PIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFN------------DTKRIDIMVTMG 343
           P KR SLEQI K  W   G  E +  P  EP P               D   ++ M ++G
Sbjct: 270 PEKRLSLEQIQKHPWYLGGKHEPD--PCLEPAPGRRVAMRSLPSNGELDPDVLESMASLG 327

Query: 344 FARDE---INDALINQKYDEVMATYILLGRK 371
             RD      +    ++  E M  Y+LL RK
Sbjct: 328 CFRDRERLHRELRSEEENQEKMIYYLLLDRK 358


>gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]
          Length = 668

 Score =  278 bits (711), Expect = 1e-74
 Identities = 144/327 (44%), Positives = 215/327 (65%), Gaps = 11/327 (3%)

Query: 56  HIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILN 115
           ++G YRL+KT+GKG    VKL  H +T ++VA+KI+++ +L+ + L K+ RE+ I+K++ 
Sbjct: 15  YVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIE 74

Query: 116 HPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQ 175
           HP+++KL +V E +K LYLV+E+ SGGE+FDYLV  GR+  KEAR  FRQI+SA+ +CH 
Sbjct: 75  HPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHS 134

Query: 176 KYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235
             I HRDLK ENLLLD   NI+IADFG ++     + L+T CGSP YA PE+ +G+KYDG
Sbjct: 135 HSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDG 194

Query: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLN 295
            + DVWS GVIL+ L+ G+LPFD  NL++L E+V RG + +P ++  DC++LL+ ++ ++
Sbjct: 195 RKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVD 254

Query: 296 PIKRGSLEQIMKDRWMNVGHEEEE--------LKPYTEPDPDFNDTKRIDIMVTMGFARD 347
             +R +LE I K  W   G  E E        ++  + P  +  D   +D M ++G  RD
Sbjct: 255 AARRLTLEHIQKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRD 314

Query: 348 E---INDALINQKYDEVMATYILLGRK 371
               + D L  ++  E M  ++LL RK
Sbjct: 315 RNKLLQDLLSEEENQEKMIYFLLLDRK 341


>gi|156105707 SNF related kinase [Homo sapiens]
          Length = 765

 Score =  270 bits (689), Expect = 5e-72
 Identities = 171/444 (38%), Positives = 251/444 (56%), Gaps = 47/444 (10%)

Query: 58  GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHP 117
           G Y L KT+G+G+FA VKLARHV TG +VAVK+IDKT+L+  +   LF+EVR MK++ HP
Sbjct: 14  GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHP 73

Query: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGR-MKEKEARAKFRQIVSAVQYCHQK 176
           NIV+L+EVI+T+  LYL++E   GG++FDY++ H   + E  A+  F QIV A+ YCH+ 
Sbjct: 74  NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133

Query: 177 YIVHRDLKAENLL-LDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235
           ++VHRDLK EN++  +    +K+ DFGFSN+F  G KL T CGS  Y+APE+  G +YD 
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193

Query: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLN 295
           P VD+WSLGVIL+ LV G  PF   N  E    ++  KY +P ++S +C++L+ ++L  +
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRD 253

Query: 296 PIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKR------IDIMVTMGFA-RDE 348
           P +R SLE+I    W+  G +      Y  P   + +         I  MV    A RD 
Sbjct: 254 PKRRASLEEIENHPWLQ-GVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDA 312

Query: 349 INDALINQKYDEVMATYILLG----RKPPEFE-GGESLSSGNLCQRSRPS---------- 393
           I +AL   +Y+ + ATY LL     R+  E E    S S  N+  + R S          
Sbjct: 313 IVEALETNRYNHITATYFLLAERILREKQEKEIQTRSASPSNIKAQFRQSWPTKIDVPQD 372

Query: 394 -------SDLNNSTL-QSPAH-----LKVQRS--ISANQKQRRFSDHAGPSIPPAVSYTK 438
                  + L+++T+ QSPA      L   RS  +  + K+    + AGP++      + 
Sbjct: 373 LEDDLTATPLSHATVPQSPARAADSVLNGHRSKGLCDSAKKDDLPELAGPALSTVPPASL 432

Query: 439 RPQANS-------VESEQKEEWDK 455
           +P A+         E E+++E DK
Sbjct: 433 KPTASGRKCLFRVEEDEEEDEEDK 456


>gi|156105705 SNF related kinase [Homo sapiens]
          Length = 765

 Score =  270 bits (689), Expect = 5e-72
 Identities = 171/444 (38%), Positives = 251/444 (56%), Gaps = 47/444 (10%)

Query: 58  GNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHP 117
           G Y L KT+G+G+FA VKLARHV TG +VAVK+IDKT+L+  +   LF+EVR MK++ HP
Sbjct: 14  GLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDTLATGHLFQEVRCMKLVQHP 73

Query: 118 NIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGR-MKEKEARAKFRQIVSAVQYCHQK 176
           NIV+L+EVI+T+  LYL++E   GG++FDY++ H   + E  A+  F QIV A+ YCH+ 
Sbjct: 74  NIVRLYEVIDTQTKLYLILELGDGGDMFDYIMKHEEGLNEDLAKKYFAQIVHAISYCHKL 133

Query: 177 YIVHRDLKAENLL-LDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDG 235
           ++VHRDLK EN++  +    +K+ DFGFSN+F  G KL T CGS  Y+APE+  G +YD 
Sbjct: 134 HVVHRDLKPENVVFFEKQGLVKLTDFGFSNKFQPGKKLTTSCGSLAYSAPEILLGDEYDA 193

Query: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLN 295
           P VD+WSLGVIL+ LV G  PF   N  E    ++  KY +P ++S +C++L+ ++L  +
Sbjct: 194 PAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMDCKYTVPSHVSKECKDLITRMLQRD 253

Query: 296 PIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKR------IDIMVTMGFA-RDE 348
           P +R SLE+I    W+  G +      Y  P   + +         I  MV    A RD 
Sbjct: 254 PKRRASLEEIENHPWLQ-GVDPSPATKYNIPLVSYKNLSEEEHNSIIQRMVLGDIADRDA 312

Query: 349 INDALINQKYDEVMATYILLG----RKPPEFE-GGESLSSGNLCQRSRPS---------- 393
           I +AL   +Y+ + ATY LL     R+  E E    S S  N+  + R S          
Sbjct: 313 IVEALETNRYNHITATYFLLAERILREKQEKEIQTRSASPSNIKAQFRQSWPTKIDVPQD 372

Query: 394 -------SDLNNSTL-QSPAH-----LKVQRS--ISANQKQRRFSDHAGPSIPPAVSYTK 438
                  + L+++T+ QSPA      L   RS  +  + K+    + AGP++      + 
Sbjct: 373 LEDDLTATPLSHATVPQSPARAADSVLNGHRSKGLCDSAKKDDLPELAGPALSTVPPASL 432

Query: 439 RPQANS-------VESEQKEEWDK 455
           +P A+         E E+++E DK
Sbjct: 433 KPTASGRKCLFRVEEDEEEDEEDK 456


>gi|46877068 AMP-activated protein kinase alpha 2 catalytic subunit
           [Homo sapiens]
          Length = 552

 Score =  267 bits (682), Expect = 3e-71
 Identities = 132/287 (45%), Positives = 190/287 (66%), Gaps = 6/287 (2%)

Query: 52  DEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRI 110
           D +  IG+Y L  T+G G F KVK+  H LTG +VAVKI+++ ++    +  K+ RE++ 
Sbjct: 8   DGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIRSLDVVGKIKREIQN 67

Query: 111 MKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
           +K+  HP+I+KL++VI T    ++VMEY SGGE+FDY+  HGR++E EAR  F+QI+SAV
Sbjct: 68  LKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAV 127

Query: 171 QYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQG 230
            YCH+  +VHRDLK EN+LLD  MN KIADFG SN  + G  L T CGSP YAAPE+  G
Sbjct: 128 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISG 187

Query: 231 KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 290
           + Y GPEVD+WS GVILY L+ G+LPFD +++  L +++  G + IP Y++     LL  
Sbjct: 188 RLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMH 247

Query: 291 LLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRID 337
           +L ++P+KR +++ I +  W      +++L  Y  P+    D   ID
Sbjct: 248 MLQVDPLKRATIKDIREHEWF-----KQDLPSYLFPEDPSYDANVID 289


>gi|94557301 protein kinase, AMP-activated, alpha 1 catalytic
           subunit isoform 1 [Homo sapiens]
          Length = 559

 Score =  266 bits (679), Expect = 7e-71
 Identities = 146/386 (37%), Positives = 229/386 (59%), Gaps = 19/386 (4%)

Query: 52  DEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRI 110
           D +  IG+Y L  T+G G F KVK+ +H LTG +VAVKI+++ ++    +  K+ RE++ 
Sbjct: 19  DGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQN 78

Query: 111 MKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAV 170
           +K+  HP+I+KL++VI T   +++VMEY SGGE+FDY+  +GR+ EKE+R  F+QI+S V
Sbjct: 79  LKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGV 138

Query: 171 QYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQG 230
            YCH+  +VHRDLK EN+LLD  MN KIADFG SN  + G  L T CGSP YAAPE+  G
Sbjct: 139 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISG 198

Query: 231 KKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKK 290
           + Y GPEVD+WS GVILY L+ G+LPFD  ++  L +++  G +  P Y++    +LLK 
Sbjct: 199 RLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKH 258

Query: 291 LLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEP-DPDFNDTKRID-----IMVTMGF 344
           +L ++P+KR +++ I +  W      +++L  Y  P DP ++ T   D     +      
Sbjct: 259 MLQVDPMKRATIKDIREHEWF-----KQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFEC 313

Query: 345 ARDEINDALINQKYDEVMAT--YILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQ 402
           + +E+   L N+ + + +A   ++++  +    E  +   +      S P S L++  L 
Sbjct: 314 SEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLA-----TSPPDSFLDDHHLT 368

Query: 403 SPAHLKVQRSISANQKQRRFSDHAGP 428
            P   +V   ++   + R   D   P
Sbjct: 369 RPHPERVPFLVAETPRARHTLDELNP 394


>gi|94557299 protein kinase, AMP-activated, alpha 1 catalytic
           subunit isoform 2 [Homo sapiens]
          Length = 574

 Score =  256 bits (653), Expect = 8e-68
 Identities = 146/401 (36%), Positives = 229/401 (57%), Gaps = 34/401 (8%)

Query: 52  DEQPHIGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQ-KLFREVRI 110
           D +  IG+Y L  T+G G F KVK+ +H LTG +VAVKI+++ ++    +  K+ RE++ 
Sbjct: 19  DGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQN 78

Query: 111 MKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGR---------------MK 155
           +K+  HP+I+KL++VI T   +++VMEY SGGE+FDY+  +GR               + 
Sbjct: 79  LKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTGSTKELD 138

Query: 156 EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDT 215
           EKE+R  F+QI+S V YCH+  +VHRDLK EN+LLD  MN KIADFG SN  + G  L T
Sbjct: 139 EKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRT 198

Query: 216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYR 275
            CGSP YAAPE+  G+ Y GPEVD+WS GVILY L+ G+LPFD  ++  L +++  G + 
Sbjct: 199 SCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFY 258

Query: 276 IPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEP-DPDFNDTK 334
            P Y++    +LLK +L ++P+KR +++ I +  W      +++L  Y  P DP ++ T 
Sbjct: 259 TPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWF-----KQDLPKYLFPEDPSYSSTM 313

Query: 335 RID-----IMVTMGFARDEINDALINQKYDEVMAT--YILLGRKPPEFEGGESLSSGNLC 387
             D     +      + +E+   L N+ + + +A   ++++  +    E  +   +    
Sbjct: 314 IDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLA---- 369

Query: 388 QRSRPSSDLNNSTLQSPAHLKVQRSISANQKQRRFSDHAGP 428
             S P S L++  L  P   +V   ++   + R   D   P
Sbjct: 370 -TSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNP 409


>gi|23503303 serine/threonine-protein kinase NIM1 [Homo sapiens]
          Length = 436

 Score =  255 bits (651), Expect = 1e-67
 Identities = 129/298 (43%), Positives = 193/298 (64%), Gaps = 8/298 (2%)

Query: 57  IGNYRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNH 116
           IG YR++  IG GNF++VKL  H LT  +VA+KI+DKT+L+  + + L RE+  M+ L+H
Sbjct: 71  IGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHH 130

Query: 117 PNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQK 176
           PNI++L+EV+ET   L+LVMEYA GGE+F  +   G++ E E++  F QIVSAV++ H+ 
Sbjct: 131 PNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHEN 190

Query: 177 YIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGP 236
            I+HRDLKAEN+    +  +K+ DFGFS     G  L+TFCGSPPYAAPELF+ + Y G 
Sbjct: 191 QIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGI 250

Query: 237 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNP 296
            VD+W+LGV+LY +V+G++PF  + + +L++ +L G Y +P ++S  C  L++ +L   P
Sbjct: 251 YVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIP 310

Query: 297 IKRGSLEQIMKDRWMNVGHEEEELKPYTEP-DPDFNDTKRIDIMVTMGFARDEINDAL 353
            +R  ++ IM D WM       +  PY  P +P   D K +    T+    +E+   L
Sbjct: 311 TERYGIDCIMNDEWM-------QGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTL 361


>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
          Length = 661

 Score =  252 bits (644), Expect = 8e-67
 Identities = 125/258 (48%), Positives = 176/258 (68%), Gaps = 2/258 (0%)

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREVRIMKILNHPN 118
           Y LQ+T+GKG + KVK A    +GR VA+K I K ++ +   +  + RE+ IM  LNHP+
Sbjct: 55  YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114

Query: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
           I+ ++EV E +  + ++MEYAS GE++DY+    R+ E+E R  FRQIVSAV YCH+  +
Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174

Query: 179 VHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEV 238
           VHRDLK EN+LLD + NIKIADFG SN +     L TFCGSP YA+PE+  G+ Y GPEV
Sbjct: 175 VHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEV 234

Query: 239 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIK 298
           D W+LGV+LYTLV G++PFDG + K L  ++  G+YR P   S D   L++ +L++NP +
Sbjct: 235 DSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPS-DARGLIRWMLMVNPDR 293

Query: 299 RGSLEQIMKDRWMNVGHE 316
           R ++E I    W+N G++
Sbjct: 294 RATIEDIANHWWVNWGYK 311


>gi|13569922 NUAK family, SNF1-like kinase, 2 [Homo sapiens]
          Length = 628

 Score =  249 bits (637), Expect = 5e-66
 Identities = 129/257 (50%), Positives = 173/257 (67%), Gaps = 3/257 (1%)

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQL-NPTSLQKLFREVRIMKILNHPN 118
           Y   +T+GKG + KVK AR   +GR VA+K I K ++ +   L  + RE+ IM  LNHP+
Sbjct: 53  YEFLETLGKGTYGKVKKARES-SGRLVAIKSIRKDKIKDEQDLMHIRREIEIMSSLNHPH 111

Query: 119 IVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYI 178
           I+ + EV E    + +VMEYAS G+++DY+    ++ E+EAR  FRQIVSAV YCHQ  +
Sbjct: 112 IIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHYCHQNRV 171

Query: 179 VHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEV 238
           VHRDLK EN+LLD + NIKIADFG SN +  G  L TFCGSP YA+PE+  GK Y GPEV
Sbjct: 172 VHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKPYTGPEV 231

Query: 239 DVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIK 298
           D WSLGV+LY LV G++PFDG + K L +++  G YR P   S  C  L++ LL++NP +
Sbjct: 232 DSWSLGVLLYILVHGTMPFDGHDHKILVKQISNGAYREPPKPSDAC-GLIRWLLMVNPTR 290

Query: 299 RGSLEQIMKDRWMNVGH 315
           R +LE +    W+N G+
Sbjct: 291 RATLEDVASHWWVNWGY 307


>gi|7661974 maternal embryonic leucine zipper kinase [Homo sapiens]
          Length = 651

 Score =  244 bits (624), Expect = 2e-64
 Identities = 135/316 (42%), Positives = 193/316 (61%), Gaps = 13/316 (4%)

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNI 119
           Y L +TIG G FAKVKLA H+LTG  VA+KI+DK  L  + L ++  E+  +K L H +I
Sbjct: 11  YELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLG-SDLPRIKTEIEALKNLRHQHI 69

Query: 120 VKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIV 179
            +L+ V+ET   +++V+EY  GGE+FDY+++  R+ E+E R  FRQIVSAV Y H +   
Sbjct: 70  CQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYA 129

Query: 180 HRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK---LDTFCGSPPYAAPELFQGKKYDGP 236
           HRDLK ENLL D    +K+ DFG   +   GNK   L T CGS  YAAPEL QGK Y G 
Sbjct: 130 HRDLKPENLLFDEYHKLKLIDFGLCAK-PKGNKDYHLQTCCGSLAYAAPELIQGKSYLGS 188

Query: 237 EVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNP 296
           E DVWS+G++LY L+ G LPFD  N+  L ++++RGKY +P ++S     LL+++L ++P
Sbjct: 189 EADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDP 248

Query: 297 IKRGSLEQIMKDRWM----NVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDA 352
            KR S++ ++   W+    N   E +   P+   D D       ++ V     R  + D 
Sbjct: 249 KKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDC----VTELSVHHRNNRQTMEDL 304

Query: 353 LINQKYDEVMATYILL 368
           +   +YD + ATY+LL
Sbjct: 305 ISLWQYDHLTATYLLL 320



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 30/110 (27%), Positives = 59/110 (53%), Gaps = 2/110 (1%)

Query: 687 RDKEEGKDSK-PRSLRFTWSMKTTSSMDPNDMMREIRKVLDANNCDYEQKERFLLFCVHG 745
           R K +G     PR L+  +++ TT  ++P+ ++ EI  +L   + D+ QK   L      
Sbjct: 543 RSKRKGSARDGPRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKGYTLKCQTQS 602

Query: 746 DARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSIAFKNIASKIANELKL 795
           D  + ++ Q+E+EVC+L +  + G+R +R+ G +  +K +   I +  K+
Sbjct: 603 DFGKVTM-QFELEVCQLQKPDVVGIRRQRLKGDAWVYKRLVEDILSSCKV 651


>gi|7657214 hormonally upregulated Neu-associated kinase [Homo
           sapiens]
          Length = 714

 Score =  233 bits (595), Expect = 4e-61
 Identities = 131/355 (36%), Positives = 217/355 (61%), Gaps = 16/355 (4%)

Query: 52  DEQPH--IGNYRL-QKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSL--QKLFR 106
           D Q H  +GNY +  + +G+G+FAKV+   HVLTG +VA+K+IDK +    +   + L R
Sbjct: 51  DFQHHKRVGNYLIGSRKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAKKDTYVTKNLRR 110

Query: 107 EVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQI 166
           E +I +++ HPNI +L +++ETE + YLVME   GG +   +    R++E EAR   RQ+
Sbjct: 111 EGQIQQMIRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQL 170

Query: 167 VSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTF---CGSPPYA 223
           +SAV++ H+  +VHRDLK ENLLLD D NIK+ DFG SN   +    D F   CGSP YA
Sbjct: 171 ISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAYA 230

Query: 224 APELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQ--NLKELRERVLRGKYR-IPFYM 280
           APEL   KKY GP++DVWS+GV +Y +++G+LPF  +  +L+ L ++++  +   +P  +
Sbjct: 231 APELLARKKY-GPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQKMVDKEMNPLPTQL 289

Query: 281 STDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVGHEEEELKPYTEPD----PDFNDTKRI 336
           ST   + L+ LL  +P+KR +++Q + +RW+N  +  +     T P+     D + +  +
Sbjct: 290 STGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTGKVPCNVTYPNRISLEDLSPSVVL 349

Query: 337 DIMVTMGFARDEINDALINQKYDEVMATYILLGRKPPEFEGGESLSSGNLCQRSR 391
            +   +G+   ++ + +++ +   ++A Y LL +K   +  G+S    +LC ++R
Sbjct: 350 HMTEKLGYKNSDVINTVLSNRACHILAIYFLLNKKLERYLSGKSDIQDSLCYKTR 404


>gi|16418343 testis-specific serine kinase 3 [Homo sapiens]
          Length = 268

 Score =  195 bits (495), Expect = 2e-49
 Identities = 106/257 (41%), Positives = 166/257 (64%), Gaps = 6/257 (2%)

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 118
           Y+L KTIG+G ++KVK A      R+VA+K+IDK       +Q+   RE++I++ L+H N
Sbjct: 10  YQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRELQIVRTLDHKN 69

Query: 119 IVKLFEVIET-EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
           I++++E++E+ +  + LVME A GG+VFD ++  G + E  A+A FRQ+V A++YCH   
Sbjct: 70  IIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCG 129

Query: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK--LDTFCGSPPYAAPELFQGKKYDG 235
           + HRDLK EN LL G  N+K+ DFGF+      ++    TFCGS  YAAPE+ QG  +D 
Sbjct: 130 VAHRDLKCENALLQG-FNLKLTDFGFAKVLPKSHRELSQTFCGSTAYAAPEVLQGIPHDS 188

Query: 236 PEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRG-KYRIPFYMSTDCENLLKKLLVL 294
            + DVWS+GV+LY ++  SLPFD  ++ ++  +  +G  +     +S DC++LLK+LL  
Sbjct: 189 KKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLSISADCQDLLKRLLEP 248

Query: 295 NPIKRGSLEQIMKDRWM 311
           + I R S+E++    W+
Sbjct: 249 DMILRPSIEEVSWHPWL 265


>gi|14042947 testis-specific serine kinase 1 [Homo sapiens]
          Length = 367

 Score =  191 bits (484), Expect = 3e-48
 Identities = 104/263 (39%), Positives = 161/263 (61%), Gaps = 13/263 (4%)

Query: 60  YRLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF-REVRIMKILNHPN 118
           Y L   +G+G++AKVK A        VA+KIID+ +     L+K   RE+ I+ +LNH +
Sbjct: 12  YLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPREIEILAMLNHCS 71

Query: 119 IVKLFEVIETEK-TLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKY 177
           I+K +E+ ET    +Y+VME A  G++ + +   G + E EAR KF Q+  A++YCH   
Sbjct: 72  IIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQLSLAIKYCHDLD 131

Query: 178 IVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNK-----LDTFCGSPPYAAPELFQGKK 232
           +VHRDLK +NLLLD D NIK++DF FS      +        TFCGSP YAAPE+ QG  
Sbjct: 132 VVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPAYAAPEVLQGIP 191

Query: 233 YDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLL 288
           Y     D+WSLGVILY +V GS+P+D  N+K++    ++ ++R+ F    +++ +C++L+
Sbjct: 192 YQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLR--IQKEHRVNFPRSKHLTGECKDLI 249

Query: 289 KKLLVLNPIKRGSLEQIMKDRWM 311
             +L  +  +R  +++I+   WM
Sbjct: 250 YHMLQPDVNRRLHIDEILSHCWM 272


>gi|194294513 testis-specific serine kinase 2 [Homo sapiens]
          Length = 358

 Score =  182 bits (463), Expect = 8e-46
 Identities = 101/258 (39%), Positives = 159/258 (61%), Gaps = 15/258 (5%)

Query: 66  IGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLF--REVRIMKILNHPNIVKLF 123
           +GKG++AKVK A        VAVKIID+ +  PT   + F  RE+ I+  +NH +I+K +
Sbjct: 18  LGKGSYAKVKSAYSERLKFNVAVKIIDRKK-TPTDFVERFLPREMDILATVNHGSIIKTY 76

Query: 124 EVIET-EKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVHRD 182
           E+ ET +  +Y++ME    G++ +++   G + E  AR  FRQ+ SAV+YCH   IVHRD
Sbjct: 77  EIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQLSSAVKYCHDLDIVHRD 136

Query: 183 LKAENLLLDGDMNIKIADFGFSNEFTVGNK-----LDTFCGSPPYAAPELFQGKKYDGPE 237
           LK ENLLLD D NIK++DFGFS      +        TFCGS  YAAPE+ Q   Y    
Sbjct: 137 LKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAAYAAPEVLQSIPYQPKV 196

Query: 238 VDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF----YMSTDCENLLKKLLV 293
            D+WSLGVILY +V GS+P+D  +++++    ++ ++R+ F     ++ +C++L+ ++L 
Sbjct: 197 YDIWSLGVILYIMVCGSMPYDDSDIRKMLR--IQKEHRVDFPRSKNLTCECKDLIYRMLQ 254

Query: 294 LNPIKRGSLEQIMKDRWM 311
            +  +R  +++I+   W+
Sbjct: 255 PDVSQRLHIDEILSHSWL 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,985,041
Number of Sequences: 37866
Number of extensions: 1443788
Number of successful extensions: 7465
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 733
Number of HSP's successfully gapped in prelim test: 229
Number of HSP's that attempted gapping in prelim test: 4348
Number of HSP's gapped (non-prelim): 1543
length of query: 795
length of database: 18,247,518
effective HSP length: 110
effective length of query: 685
effective length of database: 14,082,258
effective search space: 9646346730
effective search space used: 9646346730
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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