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Search of human proteins with 153251865
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
(1984 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 3993 0.0
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 158 4e-38
gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens] 133 2e-30
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 116 2e-25
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 110 1e-23
gi|118722349 RNA binding motif protein 12B [Homo sapiens] 103 2e-21
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 101 8e-21
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 100 1e-20
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 100 1e-20
gi|60097902 filaggrin [Homo sapiens] 96 3e-19
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 96 3e-19
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 96 3e-19
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 96 5e-19
gi|50962882 G patch domain containing 8 [Homo sapiens] 95 8e-19
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 93 3e-18
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 90 2e-17
gi|171916097 repetin [Homo sapiens] 84 2e-15
gi|50083281 KIAA1853 protein [Homo sapiens] 83 2e-15
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 83 3e-15
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 82 4e-15
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 80 2e-14
gi|4504487 histidine rich calcium binding protein precursor [Hom... 77 1e-13
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 77 2e-13
gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens] 76 4e-13
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 74 1e-12
gi|117676384 splicing factor, arginine/serine-rich 2, interactin... 73 2e-12
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 72 4e-12
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 72 4e-12
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 72 7e-12
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 72 7e-12
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 3993 bits (10356), Expect = 0.0
Identities = 1984/1984 (100%), Positives = 1984/1984 (100%)
Query: 1 MELTPGAQQQGINYQELTSGWQDVKSMMLVPEPTRKFPSGPLLTSVRFSNLSPESQQQDV 60
MELTPGAQQQGINYQELTSGWQDVKSMMLVPEPTRKFPSGPLLTSVRFSNLSPESQQQDV
Sbjct: 1 MELTPGAQQQGINYQELTSGWQDVKSMMLVPEPTRKFPSGPLLTSVRFSNLSPESQQQDV 60
Query: 61 KSLEFTVEPKLQSVKHVKLSSVSLQQTIKSVELAPGSLPQRVKYGEQTPRTNYQIMESSE 120
KSLEFTVEPKLQSVKHVKLSSVSLQQTIKSVELAPGSLPQRVKYGEQTPRTNYQIMESSE
Sbjct: 61 KSLEFTVEPKLQSVKHVKLSSVSLQQTIKSVELAPGSLPQRVKYGEQTPRTNYQIMESSE 120
Query: 121 LIPRPGHQFAKYAEMIPQPKYQIPKSANLISIPIYHATESSEMAQGLAYKGIDTVEKSVG 180
LIPRPGHQFAKYAEMIPQPKYQIPKSANLISIPIYHATESSEMAQGLAYKGIDTVEKSVG
Sbjct: 121 LIPRPGHQFAKYAEMIPQPKYQIPKSANLISIPIYHATESSEMAQGLAYKGIDTVEKSVG 180
Query: 181 LTPKLTGRAKESLGMLLQPDLQVPKFVDLTPMVRDQGSKFLGLTPEKSYQILETMELLSQ 240
LTPKLTGRAKESLGMLLQPDLQVPKFVDLTPMVRDQGSKFLGLTPEKSYQILETMELLSQ
Sbjct: 181 LTPKLTGRAKESLGMLLQPDLQVPKFVDLTPMVRDQGSKFLGLTPEKSYQILETMELLSQ 240
Query: 241 SRPRVKDVGELYMKPLQQTVEYEGITPELKHYFTEAMGLTAEARIQANEFFGMTPKPTSQ 300
SRPRVKDVGELYMKPLQQTVEYEGITPELKHYFTEAMGLTAEARIQANEFFGMTPKPTSQ
Sbjct: 241 SRPRVKDVGELYMKPLQQTVEYEGITPELKHYFTEAMGLTAEARIQANEFFGMTPKPTSQ 300
Query: 301 ATGFAERSPRLCPQNLECVEVISEKRLQGEESVVLIPKSLHHVPDSASGMTPGLGHRVPE 360
ATGFAERSPRLCPQNLECVEVISEKRLQGEESVVLIPKSLHHVPDSASGMTPGLGHRVPE
Sbjct: 301 ATGFAERSPRLCPQNLECVEVISEKRLQGEESVVLIPKSLHHVPDSASGMTPGLGHRVPE 360
Query: 361 SVELTSKSGVQVEKTLQLTPKPQHHVGSPGIISGLGHQVPESVNLTCKQWLQMEESLEVP 420
SVELTSKSGVQVEKTLQLTPKPQHHVGSPGIISGLGHQVPESVNLTCKQWLQMEESLEVP
Sbjct: 361 SVELTSKSGVQVEKTLQLTPKPQHHVGSPGIISGLGHQVPESVNLTCKQWLQMEESLEVP 420
Query: 421 LKQTSQVIGHEESVELTSEARQHREVSMGLTKSKNQSMKSPGTTPGPLGRIVEFMRISPE 480
LKQTSQVIGHEESVELTSEARQHREVSMGLTKSKNQSMKSPGTTPGPLGRIVEFMRISPE
Sbjct: 421 LKQTSQVIGHEESVELTSEARQHREVSMGLTKSKNQSMKSPGTTPGPLGRIVEFMRISPE 480
Query: 481 PLDQVTESARTQLQVAQSEEVILIDVPKVVQSVKVTPGPPFQIVKSVTIPRPTPQMVEYI 540
PLDQVTESARTQLQVAQSEEVILIDVPKVVQSVKVTPGPPFQIVKSVTIPRPTPQMVEYI
Sbjct: 481 PLDQVTESARTQLQVAQSEEVILIDVPKVVQSVKVTPGPPFQIVKSVTIPRPTPQMVEYI 540
Query: 541 ELTPKLQYVRPSEHHTGPCLQDVKSTKLITKPKHQILETVELTGFQIVKTMLIPGPSLQI 600
ELTPKLQYVRPSEHHTGPCLQDVKSTKLITKPKHQILETVELTGFQIVKTMLIPGPSLQI
Sbjct: 541 ELTPKLQYVRPSEHHTGPCLQDVKSTKLITKPKHQILETVELTGFQIVKTMLIPGPSLQI 600
Query: 601 VKSEELAPGPIPQVVEPIGVALESGIEAINCVDLLPRPHLQELIVPAELTPSPCTQVKSA 660
VKSEELAPGPIPQVVEPIGVALESGIEAINCVDLLPRPHLQELIVPAELTPSPCTQVKSA
Sbjct: 601 VKSEELAPGPIPQVVEPIGVALESGIEAINCVDLLPRPHLQELIVPAELTPSPCTQVKSA 660
Query: 661 ELTSPQTSPFEEHTILTHKQGLQAVKSTVIKTEPPKVMETEDLNLGHVCQNRDCQKLTSE 720
ELTSPQTSPFEEHTILTHKQGLQAVKSTVIKTEPPKVMETEDLNLGHVCQNRDCQKLTSE
Sbjct: 661 ELTSPQTSPFEEHTILTHKQGLQAVKSTVIKTEPPKVMETEDLNLGHVCQNRDCQKLTSE 720
Query: 721 ELQVGTDFSRFLQSSSTTLISSSVRTASELGGLWDSGIQEVSRALDIKNPGTDILQPEET 780
ELQVGTDFSRFLQSSSTTLISSSVRTASELGGLWDSGIQEVSRALDIKNPGTDILQPEET
Sbjct: 721 ELQVGTDFSRFLQSSSTTLISSSVRTASELGGLWDSGIQEVSRALDIKNPGTDILQPEET 780
Query: 781 YIDPTMIQSLTFPLALHNQSSDKTANIVENPCPEILGVDVISKETTKRKQMEELENSLQR 840
YIDPTMIQSLTFPLALHNQSSDKTANIVENPCPEILGVDVISKETTKRKQMEELENSLQR
Sbjct: 781 YIDPTMIQSLTFPLALHNQSSDKTANIVENPCPEILGVDVISKETTKRKQMEELENSLQR 840
Query: 841 HLPQSWRSRSRTFQAESGVQKGLIKSFPGRQHNVWESHAWRQRLPRKYLSTMLMLGNILG 900
HLPQSWRSRSRTFQAESGVQKGLIKSFPGRQHNVWESHAWRQRLPRKYLSTMLMLGNILG
Sbjct: 841 HLPQSWRSRSRTFQAESGVQKGLIKSFPGRQHNVWESHAWRQRLPRKYLSTMLMLGNILG 900
Query: 901 TTMERKLCSQTSLAERATADTCQSIQNLFGIPAELMEPSQSLPEKGPVTISQPSVVKNYI 960
TTMERKLCSQTSLAERATADTCQSIQNLFGIPAELMEPSQSLPEKGPVTISQPSVVKNYI
Sbjct: 901 TTMERKLCSQTSLAERATADTCQSIQNLFGIPAELMEPSQSLPEKGPVTISQPSVVKNYI 960
Query: 961 QRHTFYHGHKKRMALRIWTRGSTSSIIQQYSGTRVRIKKTNSTFNGISQEVIQHMPVSCA 1020
QRHTFYHGHKKRMALRIWTRGSTSSIIQQYSGTRVRIKKTNSTFNGISQEVIQHMPVSCA
Sbjct: 961 QRHTFYHGHKKRMALRIWTRGSTSSIIQQYSGTRVRIKKTNSTFNGISQEVIQHMPVSCA 1020
Query: 1021 GGQLPVLVKSESSLSIFYDREDLVPMEESEDSQSDSQTRISESQHSLKPNYLSQAKTDFS 1080
GGQLPVLVKSESSLSIFYDREDLVPMEESEDSQSDSQTRISESQHSLKPNYLSQAKTDFS
Sbjct: 1021 GGQLPVLVKSESSLSIFYDREDLVPMEESEDSQSDSQTRISESQHSLKPNYLSQAKTDFS 1080
Query: 1081 EQFQLLEDLQLKIAAKLLRSQIPPDVPPPLASGLVLKYPICLQCGRCSGLNCHHKLQTTS 1140
EQFQLLEDLQLKIAAKLLRSQIPPDVPPPLASGLVLKYPICLQCGRCSGLNCHHKLQTTS
Sbjct: 1081 EQFQLLEDLQLKIAAKLLRSQIPPDVPPPLASGLVLKYPICLQCGRCSGLNCHHKLQTTS 1140
Query: 1141 GPYLLIYPQLHLVRTPEGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRK 1200
GPYLLIYPQLHLVRTPEGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRK
Sbjct: 1141 GPYLLIYPQLHLVRTPEGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRK 1200
Query: 1201 AKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVH 1260
AKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVH
Sbjct: 1201 AKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVH 1260
Query: 1261 NLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAA 1320
NLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAA
Sbjct: 1261 NLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAA 1320
Query: 1321 HLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTR 1380
HLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTR
Sbjct: 1321 HLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTR 1380
Query: 1381 PDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQ 1440
PDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQ
Sbjct: 1381 PDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQ 1440
Query: 1441 PRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQES 1500
PRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQES
Sbjct: 1441 PRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQES 1500
Query: 1501 KNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHN 1560
KNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHN
Sbjct: 1501 KNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHN 1560
Query: 1561 PSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPER 1620
PSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPER
Sbjct: 1561 PSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPER 1620
Query: 1621 SCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRG 1680
SCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRG
Sbjct: 1621 SCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRG 1680
Query: 1681 PSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSER 1740
PSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSER
Sbjct: 1681 PSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSER 1740
Query: 1741 SHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHS 1800
SHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHS
Sbjct: 1741 SHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHS 1800
Query: 1801 PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERS 1860
PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERS
Sbjct: 1801 PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERS 1860
Query: 1861 RCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRP 1920
RCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRP
Sbjct: 1861 RCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRP 1920
Query: 1921 SGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRP 1980
SGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRP
Sbjct: 1921 SGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRP 1980
Query: 1981 EATR 1984
EATR
Sbjct: 1981 EATR 1984
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 158 bits (400), Expect = 4e-38
Identities = 198/783 (25%), Positives = 290/783 (37%), Gaps = 122/783 (15%)
Query: 1219 SGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKRAKV 1278
S PS S AP + P ++ TK+ P + V P + S + +K
Sbjct: 8 SKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNR---SLVPTKPATSRNSVMSPSSSK- 63
Query: 1279 RTKKTSDSKYPMKRITKRLRKHRK------FYTNSRTTIESPSRELAAHLRRKRIGATQT 1332
TK TS + P R + R R K T++RT+ S + ++ H RR +T
Sbjct: 64 STKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRT 123
Query: 1333 ----STASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASK 1388
+ S KR P + S P GR G RP
Sbjct: 124 PGRRGSRSSKRSPSRASTP------------------------GRIRTHGARPGM----- 154
Query: 1389 NYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQ 1448
A P+S ++ R P S ++ D QPR
Sbjct: 155 -------ASRVRTPTSQQKGSRGKSYGRPRTSNRERSD------------SQPRNLSKKS 195
Query: 1449 PRPLRLPKPT----DSQSGIAFQTASVGQPLRTVQKD-------SSSRSKKNFYRNETSS 1497
RP P + S+ + TA P K+ SSSR K++ + S
Sbjct: 196 YRP---PGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPS 252
Query: 1498 QESKNLSTP-GTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSER 1556
+E T +RV++ + S + +H + P R + + R
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQ-----------SHSQSRSPRRSRSGSQKRTHSR 301
Query: 1557 TRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSER----SW-RSPSQ 1611
R + RNH R+++ L + RSH +N S R +W R+PS+
Sbjct: 302 VRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSK 361
Query: 1612 RNHCSPPERSCHSLSERGLHSPSQRSHRG----PSQRRHHSPSERSHRSPSERSHRSSSE 1667
S S RG SP + S R P+++R HS S RSP++ RS S
Sbjct: 362 ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRS----RSPNKARDRSRSR 417
Query: 1668 RRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHR 1727
+++ + R P++ CS S +++ + R P++ R HS S+ +++ R R
Sbjct: 418 SPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSR 477
Query: 1728 SPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSE 1787
SPS+ HS RR SPS+ C S S RR RSPS+ R S
Sbjct: 478 SPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR 537
Query: 1788 KSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHR-SFERSHRRISERSH 1846
+ SPSE R H R RSPS+ R R S S R RS
Sbjct: 538 SPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSR 597
Query: 1847 SPSEKSHLS-------PLERSRCSPSERRGHSSSGKTCHSPSERSH----RSPSGMRQ-G 1894
SP+++S S SR + G+ S +T S+ S RSP R
Sbjct: 598 SPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPT 657
Query: 1895 RTSERS-HRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHS 1953
RTS S +R+ + + HSPS PSG S + + K + PGER S S
Sbjct: 658 RTSSLSQNRTPSKTSSHSPSTF----PSGGQTLSQDDSQADATTS---KATLPGERSSSS 710
Query: 1954 LSR 1956
S+
Sbjct: 711 SSK 713
>gi|239749693 PREDICTED: similar to hCG1806822 [Homo sapiens]
Length = 1180
Score = 133 bits (335), Expect = 2e-30
Identities = 113/416 (27%), Positives = 138/416 (33%), Gaps = 14/416 (3%)
Query: 1543 SFYRERTPRG-----PSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKN 1597
S YR R P P H+P + SP S HSP + SP
Sbjct: 39 SLYRRRAPEAAVFHSPEAAVYHSPEATVYHSPEAAVYHSPEAAVFHSPEAAVYHSPEAAV 98
Query: 1598 HSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSP 1657
+ SP + SP + SP HS HSP +R P SP +RSP
Sbjct: 99 YHSPEAAVFHSPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYRSPEAAVFRSPEAAVYRSP 158
Query: 1658 SERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRS 1717
RS +RSP R P + SP +RSP P H P
Sbjct: 159 EAAVFRSPEAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHSPEAAVFHCPEAAV 218
Query: 1718 HRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSP 1777
+RSP +RSP H P +HSP +HSP SP SP + SP
Sbjct: 219 YRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSP 278
Query: 1778 SERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERS 1837
+HSP +HSP +HSP HSP HS SP H
Sbjct: 279 GAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPG--- 335
Query: 1838 HRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTS 1897
+ HSP + SP SP S SP +RSP
Sbjct: 336 ----AAVFHSPGAAVYHSPGAAVYHSPGAAVFRSPGAAVFRSPGAAVYRSPEAAVFRSPE 391
Query: 1898 ERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHS 1953
+RS SP P + SP SP E + PG HS
Sbjct: 392 AAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSP--EASVFHSPGAAVFHS 445
Score = 124 bits (311), Expect = 9e-28
Identities = 103/384 (26%), Positives = 124/384 (32%), Gaps = 7/384 (1%)
Query: 1553 PSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQR 1612
P H+P SP S +HSP + SP + SP + SP
Sbjct: 254 PEASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPGAAVYHSPGAA 313
Query: 1613 NHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRS 1672
SP HS HSP P +HSP + SP RS RS
Sbjct: 314 VFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFRSPGAAVFRS 373
Query: 1673 PSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER 1732
P +R P SP +RSP +R P H P + SP + SP
Sbjct: 374 PGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEAS 433
Query: 1733 SHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHS 1792
HSP HSP +HSP SP + SP + SP HSP +HS
Sbjct: 434 VFHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVYHS 493
Query: 1793 PSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKS 1852
P HSP HSP HS +RSP +R SP
Sbjct: 494 PGAAVFHSPGAAVYHSPGAAVFHSPGAAVYRSPGAAVFRSPGAAVYR-------SPGAAV 546
Query: 1853 HLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSP 1912
SP SP S SP +RSP +RS SP
Sbjct: 547 FRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSP 606
Query: 1913 SEMRPGRPSGRNHCSPSERSRRSP 1936
P + SP RSP
Sbjct: 607 GAAVYRSPGAAVYRSPGAAVFRSP 630
Score = 120 bits (301), Expect = 1e-26
Identities = 101/385 (26%), Positives = 123/385 (31%), Gaps = 1/385 (0%)
Query: 1553 PSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQR 1612
P H+P + SP S HSP + SP + SP + SP
Sbjct: 238 PEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVYHSPGAA 297
Query: 1613 NHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRS 1672
+ SP HS HSP P HSP SP + S + S
Sbjct: 298 VYHSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPGAAVYHS 357
Query: 1673 PSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER 1732
P R P SP +RSP R P + SP +RSP P
Sbjct: 358 PGAAVFRSPGAAVFRSPGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAA 417
Query: 1733 SHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHS 1792
+HSP +HSP HSP SP + SP SP +HSP +HS
Sbjct: 418 VYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHS 477
Query: 1793 PSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISER-SHSPSEK 1851
P HSP HSP HS + SP H +R SP
Sbjct: 478 PGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYRSPGAAVFRSPGAA 537
Query: 1852 SHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHS 1911
+ SP SP S SP +RSP +RS S
Sbjct: 538 VYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRS 597
Query: 1912 PSEMRPGRPSGRNHCSPSERSRRSP 1936
P P + SP RSP
Sbjct: 598 PGAAVYRSPGAAVYRSPGAAVYRSP 622
Score = 119 bits (297), Expect = 4e-26
Identities = 102/386 (26%), Positives = 121/386 (31%), Gaps = 7/386 (1%)
Query: 1551 RGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPS 1610
R P H P + SP S HSP SP + SP + SP
Sbjct: 228 RSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPG 287
Query: 1611 QRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRH 1670
+ SP HS HSP P HSP SP S +
Sbjct: 288 AAVYHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVY 347
Query: 1671 RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPS 1730
SP + P SP RSP +R P SP +RSP +RSP
Sbjct: 348 HSPGAAVYHSPGAAVFRSPGAAVFRSPGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPE 407
Query: 1731 ERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSH 1790
H P +HSP +HSP SP SP + SP HSP +
Sbjct: 408 AAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVY 467
Query: 1791 HSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSE 1850
HSP +HSP HSP HS SP H + HSP
Sbjct: 468 HSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPG-------AAVFHSPGA 520
Query: 1851 KSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRH 1910
+ SP SP S SP +RSP +RS
Sbjct: 521 AVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYR 580
Query: 1911 SPSEMRPGRPSGRNHCSPSERSRRSP 1936
SP P + SP RSP
Sbjct: 581 SPGAAVYRSPGAAVYRSPGAAVYRSP 606
Score = 112 bits (280), Expect = 4e-24
Identities = 101/394 (25%), Positives = 122/394 (30%), Gaps = 15/394 (3%)
Query: 1551 RGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPS 1610
R P +P +RSP RS HSP P + SP +RSP
Sbjct: 172 RSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHSPEAAVFHCPEAAVYRSPEAAVYRSPE 231
Query: 1611 QRN-HC-------SPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSH 1662
HC SP HS HSP P +HSP + SP +
Sbjct: 232 AAVFHCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVY 291
Query: 1663 RSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPA 1722
S + SP + P SP SP P HSP + SP
Sbjct: 292 HSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVFHSPGAAVYHSPG 351
Query: 1723 RRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRH 1782
+ SP SP SP + SP SP + SP +RSP
Sbjct: 352 AAVYHSPGAAVFRSPGAAVFRSPGAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVF 411
Query: 1783 HSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRIS 1842
H P +HSP +HSP HSP HS + SP H +
Sbjct: 412 HCPEAAVYHSPEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVY---- 467
Query: 1843 ERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHR 1902
HSP + SP SP HS HSP + SP +R
Sbjct: 468 ---HSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYR 524
Query: 1903 SSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936
S SP P SP RSP
Sbjct: 525 SPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSP 558
Score = 109 bits (272), Expect = 3e-23
Identities = 96/361 (26%), Positives = 128/361 (35%), Gaps = 7/361 (1%)
Query: 1553 PSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQR 1612
P H+P SP S +HSP SP + SP + SP
Sbjct: 422 PEAAVYHSPEASVFHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHSPGAA 481
Query: 1613 NHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRS 1672
SP HS HSP + P HSP +RSP RS +RS
Sbjct: 482 VFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVFHSPGAAVYRSPGAAVFRSPGAAVYRS 541
Query: 1673 PSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER 1732
P R P + SP RSP +R P + SP +RSP +RSP
Sbjct: 542 PGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAA 601
Query: 1733 SHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHS 1792
+ SP + SP + SP SP + SP RSP + SP + S
Sbjct: 602 VYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRS 661
Query: 1793 PSERSHHSPSERRRHSP---LERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPS 1849
P + SP SP + RS + + RS + R + RS RS +
Sbjct: 662 PGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSRGAAVYRSRGAA 721
Query: 1850 -EKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERT 1908
+S + + R SP S SP +RSP G RS ++ R+
Sbjct: 722 VYRSRGAAVYR---SPGAAVYRSREAAVFRSPEAAVYRSPEAAVPGAAVYRSPGAAVYRS 778
Query: 1909 R 1909
R
Sbjct: 779 R 779
Score = 102 bits (255), Expect = 3e-21
Identities = 97/400 (24%), Positives = 131/400 (32%), Gaps = 18/400 (4%)
Query: 1551 RGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPS 1610
R P +P +RSP RS H P + SP + SP + SP
Sbjct: 380 RSPEAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPG 439
Query: 1611 QRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRH 1670
SP HS HSP + P +HSP SP + S
Sbjct: 440 AAVFHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVYHSPGAAVFHSPGAAVYHSPGAAVF 499
Query: 1671 RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPS 1730
SP + P SP +RSP R P + SP RSP +RSP
Sbjct: 500 HSPGAAVYHSPGAAVFHSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPG 559
Query: 1731 ERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSH 1790
SP + SP + SP + SP + SP +RSP + SP +
Sbjct: 560 AAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVY 619
Query: 1791 HSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSE 1850
SP SP SP S +RSP + SP
Sbjct: 620 RSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPG---------------AAVYRSPGA 664
Query: 1851 KSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSG---MRQGRTSERSHRSSCER 1907
+ SP SP S SP +RSP +G RS ++ R
Sbjct: 665 AVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSRGAAVYRSRGAAVYR 724
Query: 1908 TRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPG 1947
+R + PG R+ + RS + + + + PG
Sbjct: 725 SRGAAVYRSPGAAVYRSREAAVFRSPEAAVYRSPEAAVPG 764
Score = 99.8 bits (247), Expect = 2e-20
Identities = 99/400 (24%), Positives = 131/400 (32%), Gaps = 18/400 (4%)
Query: 1553 PSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQR 1612
P H+P +RSP RS + SP SP + SP +RSP
Sbjct: 510 PGAAVFHSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAA 569
Query: 1613 NHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRS 1672
+ SP S SP +R P + SP +RSP +RS RS
Sbjct: 570 VYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRS 629
Query: 1673 PSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER 1732
P +R P SP +RSP +R P + SP RSP +RSP
Sbjct: 630 PGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVYRSPGAA 689
Query: 1733 SHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHS 1792
+ SP + SP + S + S + S +RSP + S S
Sbjct: 690 VYRSPGAAVYRSPGAAVYRSRGAAVYRSRGAAVYRSRGAAVYRSPGAAVYRSREAAVFRS 749
Query: 1793 PSERSHHSPSE----------------RRRHSPLERSRHSLLERSHRSPSERRSHRSFER 1836
P + SP R R + + RSR + + RS + R + R
Sbjct: 750 PEAAVYRSPEAAVPGAAVYRSPGAAVYRSRGAAVYRSRGAAVYRSRGAAVYRSPGAAVYR 809
Query: 1837 SHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRT 1896
S R SP + SP SP H HSP + SP
Sbjct: 810 SREAAVFR--SPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVFHSP 867
Query: 1897 SERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936
+ S HSP P SP RSP
Sbjct: 868 EAAVYHSPEAAVFHSPGAAVFHSPGAAVFHSPGAAVYRSP 907
Score = 96.3 bits (238), Expect = 3e-19
Identities = 92/379 (24%), Positives = 126/379 (33%), Gaps = 20/379 (5%)
Query: 1566 HRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSL 1625
+RSP RS SP + SP + SP + P + SP HS
Sbjct: 800 YRSPGAAVYRSREAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSP 859
Query: 1626 SERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERS 1685
HSP + P HSP SP S +RSP +R P
Sbjct: 860 EASVFHSPEAAVYHSPEAAVFHSPGAAVFHSPGAAVFHSPGAAVYRSPGAAVYRSPGAAV 919
Query: 1686 HCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSP 1745
+ SP +RSP +R P SP RSP +RSP SP + SP
Sbjct: 920 YRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSP 979
Query: 1746 SERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERR 1805
SP + SP SP +RSP SP P +HSP E
Sbjct: 980 GAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVFRCPEAAVYHSP-EAT 1038
Query: 1806 RHSPLERSRHSLLERS--HRSPSERRSHRSFE-RSHRR---ISERSHSPSEKSHLSPLER 1859
+ R E + R+P R RSH R + + +P + P R
Sbjct: 1039 VYPAWRRGESDSAETNFQDRTPIGGPGPRGPSLRSHPRSGPCAGKPRAPRSRGAAEPPSR 1098
Query: 1860 SRCSP-------SERRGHSSSGKTCHSPSERSHR------SPSGMRQGRTSERSHRSSCE 1906
+P + + + + + + SER R + + GR R R +
Sbjct: 1099 RVAAPGVGTAGGANKAAATRAAQARDARSERPRRAFVSGGAGAAAAAGRPERRMRRPAAR 1158
Query: 1907 RTRHSPSEMRPGRPSGRNH 1925
+R RP R H
Sbjct: 1159 IGERCGDWLRGARPGARRH 1177
Score = 89.0 bits (219), Expect = 4e-17
Identities = 95/391 (24%), Positives = 121/391 (30%), Gaps = 20/391 (5%)
Query: 1551 RGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPS 1610
R P +P +RSP RS + SP SP + SP +RSP
Sbjct: 604 RSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPG 663
Query: 1611 QRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRH 1670
+ SP S SP +R P + SP +RS +RS +
Sbjct: 664 AAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSRGAAVYRSRGAAVY 723
Query: 1671 RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERR-----HHSPSKRSHRSPARRS 1725
RS +R P + S RSP +R P + SP +RS
Sbjct: 724 RSRGAAVYRSPGAAVYRSREAAVFRSPEAAVYRSPEAAVPGAAVYRSPGAAVYRSRGAAV 783
Query: 1726 HRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSP 1785
+RS + S + SP + S SP + SP +RSP H P
Sbjct: 784 YRSRGAAVYRSRGAAVYRSPGAAVYRSREAAVFRSPEAAVYRSPEAAVYRSPEAAVFHCP 843
Query: 1786 SEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERS 1845
+HSP +HSP HSP HS SP +
Sbjct: 844 EAAVYHSPEAAVYHSPEASVFHSPEAAVYHSPEAAVFHSPG---------------AAVF 888
Query: 1846 HSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSC 1905
HSP SP SP S SP +RSP RS
Sbjct: 889 HSPGAAVFHSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPG 948
Query: 1906 ERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936
SP P SP RSP
Sbjct: 949 AAVFRSPGAAVYRSPGAAVFRSPGAAVYRSP 979
Score = 88.2 bits (217), Expect = 7e-17
Identities = 94/391 (24%), Positives = 122/391 (31%), Gaps = 20/391 (5%)
Query: 1551 RGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPS 1610
R P +P +RSP RS SP + SP SP +RSP
Sbjct: 596 RSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVFRSPGAAVYRSPG 655
Query: 1611 QRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRH 1670
+ SP S SP +R P + SP +RSP +RS +
Sbjct: 656 AAVYRSPGAAVYRSPGAAVFRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSRGAAVY 715
Query: 1671 RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRS-----HRSPARRS 1725
RS +R + SP +RS R P + SP +RSP
Sbjct: 716 RSRGAAVYRSRGAAVYRSPGAAVYRSREAAVFRSPEAAVYRSPEAAVPGAAVYRSPGAAV 775
Query: 1726 HRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSP 1785
+RS + S + S + SP + S SP +RSP + SP
Sbjct: 776 YRSRGAAVYRSRGAAVYRSRGAAVYRSPGAAVYRSREAAVFRSPEAAVYRSPEAAVYRSP 835
Query: 1786 SEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERS 1845
H P +HSP HSP HS + SP +
Sbjct: 836 EAAVFHCPEAAVYHSPEAAVYHSPEASVFHSPEAAVYHSPE---------------AAVF 880
Query: 1846 HSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSC 1905
HSP SP SP S SP +RSP +RS
Sbjct: 881 HSPGAAVFHSPGAAVFHSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPGAAVYRSPG 940
Query: 1906 ERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936
SP P + SP RSP
Sbjct: 941 AAVFRSPGAAVFRSPGAAVYRSPGAAVFRSP 971
Score = 74.3 bits (181), Expect = 1e-12
Identities = 73/276 (26%), Positives = 91/276 (32%), Gaps = 5/276 (1%)
Query: 1680 GPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSE 1739
G ++ + C + + S R P HSP + SP + SP +HSP
Sbjct: 21 GGTDSNFCCCCCQMSKEVSLYRRRAPEAAVFHSPEAAVYHSPEATVYHSPEAAVYHSPEA 80
Query: 1740 RSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHH 1799
HSP +HSP + SP SP + SP HSP HSP +
Sbjct: 81 AVFHSPEAAVYHSPEAAVYHSPEAAVFHSPEAAVYHSPEAAVFHSPEAAVFHSPEAAVYR 140
Query: 1800 SPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERS--HSPSEKSHLSPL 1857
SP SP S RSP E +RS E + R E + SP + SP
Sbjct: 141 SPEAAVFRSPEAAVYRSPEAAVFRSP-EAAVYRSPEAAVFRSPEAAVYRSPEAAVYRSPE 199
Query: 1858 ERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRP 1917
SP H SP +RSP + S HSP
Sbjct: 200 AAVFHSPEAAVFHCPEAAVYRSPEAAVYRSPEAAVFHCPEAAVYHSPEAAVYHSPEASVF 259
Query: 1918 GRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHS 1953
P SP SP Y PG HS
Sbjct: 260 HSPGAAVFHSPGAAVYHSP--GAAVYHSPGAAVYHS 293
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 116 bits (290), Expect = 2e-25
Identities = 196/744 (26%), Positives = 289/744 (38%), Gaps = 111/744 (14%)
Query: 1281 KKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQTSTASLKRQ 1340
+++S S+ P K+ +K +K R+ SP RE ++K+ ++ + S KR+
Sbjct: 175 RESSSSRSPTP---KQKKKKKKKDRGRRSESSSPRRERKKSSKKKK---HRSESESKKRK 228
Query: 1341 PKKPSQPKFMQLLFQSLKRAFQT--------AHRVIASVGRKPVDGTRPDNLWASKNYYP 1392
+ P+ + + KR+ T AHR ++ D +R + A+ +
Sbjct: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288
Query: 1393 KQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSA-------QQPRRAY 1445
A P+S +R + A P ++ ++ T Q S ++ + A
Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348
Query: 1446 SFQPRPLRL---PKPTDSQSGIAFQTASVGQPLRTV---QKDSSSRSKKNFYRN------ 1493
P P R P+P +A + QPL T Q+ + S+ + R+
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408
Query: 1494 -----ETSSQESKNLSTPGTRVQARGRILPGSPVKRT---WHRHLKDKLTHKEHNHPSFY 1545
++SS ES S T+V P SP HR + T K +H
Sbjct: 409 PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468
Query: 1546 RERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC-SPSRKNHSSPSER 1604
R+++ H PS R RS S + + R +P++R H S S + S S +
Sbjct: 469 RDKS-------HSHTPSRRMGRSRSPATAKRG-RSRSRTPTKRGHSRSRSPQWRRSRSAQ 520
Query: 1605 SW---RSPSQRNHCSPPERSCHSLSE------RGLHSPSQRSH-RGPSQR---RHHSPSE 1651
W RSP +R P+R S S R + RSH R P+ R R +P+
Sbjct: 521 RWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPAR 580
Query: 1652 RSH---RSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSER 1708
R R+P+ R RS + R RS S+ R RS +P+ RR R+ S R
Sbjct: 581 RGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSR-TPARRRSRTRSPVRRRS---- 635
Query: 1709 RHHSPSKRSHRS----PARRSH---RSPSERSH---HSPSERSHHSPSERRHHSPSERSH 1758
R SP++RS RS PARR R+P+ R +P+ RS S S RS
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSR 695
Query: 1759 CSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLL 1818
RS RR RS S S +S S R +S E + +
Sbjct: 696 TPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRIS 755
Query: 1819 ERSHRSPSERRSHRSFERSHRR-ISERSHSPSEKSHLSPLERSRCSPSE---------RR 1868
R RS S RS S RR +S S P +KS +P RSR S+ RR
Sbjct: 756 SRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQ-TPPRRSRSGSSQPKAKSRTPPRR 814
Query: 1869 GHSSSG----KTCHSPSERSHRSPS---------GMRQGR-TSERSHRSSCERTRHSPSE 1914
SSS + +PS +SH S S RQG TS +++ S R S E
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
Query: 1915 MRP-----GRPSGRNHCSPSERSR 1933
P R R+ CS S R
Sbjct: 875 SSPDPELKSRTPSRHSCSGSSPPR 898
Score = 97.8 bits (242), Expect = 9e-20
Identities = 138/508 (27%), Positives = 197/508 (38%), Gaps = 99/508 (19%)
Query: 1531 KDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSH 1590
KD+ E + P R+++ + R+ R HRSP+ +S+R S +++ +
Sbjct: 194 KDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP 253
Query: 1591 CSPSRKNHSSPS-ERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRG--------- 1640
SR+ H S S + + S + R+ H+ + G SPS S R
Sbjct: 254 APKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG-RSPSPASGRRGEGDAPFSE 312
Query: 1641 ---PSQRRHHSPSERSHR--SPSERSHRSSSERRHRSPS---QRSHRGP---------SE 1683
S +R SP + + SP E + E+ PS +RS GP +E
Sbjct: 313 PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE 372
Query: 1684 RSHCSP-------------------SERRHRSPSQRSHRGPSER---------------R 1709
R SP S R RSP + + P R
Sbjct: 373 RHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR 432
Query: 1710 HHSPSKRSHR-SPARRSHRSPSE------RSH-HSPSERSH-HSPSER--RHHSPSERSH 1758
H S S S + +PA SHR S RSH + ++SH H+PS R R SP+
Sbjct: 433 HASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKR 492
Query: 1759 CSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLL 1818
R+ R RSP RR S +R S S +R RSR++
Sbjct: 493 GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQR--PGWSRSRNT-- 548
Query: 1819 ERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCH 1878
+R RS S RR R RS +P+ + RSR +P+ RR S
Sbjct: 549 QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR----SRSR-TPARRRSRS------R 597
Query: 1879 SPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMR-----PGRPSGRNHC-SPSERS 1932
+P+ R RS + R+GR+ R+ RTR SP R P R SGR+ +P+ R
Sbjct: 598 TPTRRRSRSRTPARRGRSRSRTPARRRSRTR-SPVRRRSRSRSPARRSGRSRSRTPARRG 656
Query: 1933 R---RSPLKEGLKYS-FPGERPSHSLSR 1956
R R+P + G S P R S SR
Sbjct: 657 RSRSRTPARRGRSRSRTPARRSGRSRSR 684
Score = 97.8 bits (242), Expect = 9e-20
Identities = 164/574 (28%), Positives = 215/574 (37%), Gaps = 86/574 (14%)
Query: 1415 LTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQP---RPLRLPKPTDSQSGIAFQTASV 1471
LTP E + TV Q R+ S Q +P P+ A
Sbjct: 1510 LTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKT 1569
Query: 1472 GQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLK 1531
PLR Q+ S S + ++ S + S++ S+P V+ + R P R
Sbjct: 1570 RTPLR--QRSRSGSSPEVDSKSRLSPRRSRSGSSP--EVKDKPRAAP---------RAQS 1616
Query: 1532 DKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC 1591
+ E P+ PR R+R S + R PS S+ H P R+
Sbjct: 1617 GSDSSPEPKAPA------PRALPRRSRSGSSSKG-RGPSPEGSSSTESSPEHPPKSRTAR 1669
Query: 1592 SPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSE 1651
SR + P +S P +R+ S PE L+ + S RS + R +P
Sbjct: 1670 RGSRSS-PEPKTKSRTPPRRRSSRSSPE-----LTRKARLSRRSRSASSSPETRSRTPP- 1722
Query: 1652 RSHRSPS----ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSER-----RHRSPSQRSH 1702
R RSPS E + +S S RR RS S + S R SPS + R RS S+R
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR-SPSPKPRGLQRSRSRSRREK 1781
Query: 1703 RGPSERRHHSPSKRS---------HRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP 1753
+ RR S S +S RS R R S SP+ + S RR
Sbjct: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841
Query: 1754 S---------ERSHCSPS----ERSHCSPSERRH---RSPSERRHHSPSEKSHHS-PSER 1796
S RS SP+ RS SP+ R R+P R S S S S R
Sbjct: 1842 SRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSR 1901
Query: 1797 SHHSPSERR---RHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSP----- 1848
S S + RR R SP+ R R RS P RR RS + RR S RS +P
Sbjct: 1902 SRTSVTRRRSRSRASPVSRRR----SRSRTPPVTRRRSRSRTPTTRRRS-RSRTPPVTRR 1956
Query: 1849 SEKSHLSPL----ERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSS 1904
+S P+ RSR SP RR S RS SP R+ R+
Sbjct: 1957 RSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRR 2016
Query: 1905 CERTRHSPSEMRPGRPSGRNHCSPSERSR-RSPL 1937
R+R P+ R R R P +RSR RSPL
Sbjct: 2017 RSRSRTPPAIRR--RSRSRTPLLPRKRSRSRSPL 2048
Score = 95.1 bits (235), Expect = 6e-19
Identities = 147/493 (29%), Positives = 186/493 (37%), Gaps = 110/493 (22%)
Query: 1546 RERTPRGPSERTRH--NPSWRNHR-SPSERSQRSS---LERRHHSPSQ-RSHCSPSRKNH 1598
++ PR PS R+R +P R+ +PS S S ++ +PS+ RS C S +
Sbjct: 1428 KDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK 1487
Query: 1599 SSPS-----ERSWRSPSQRNHCSPPERSCHSLSERGLHSPS-------QRSHRGPSQRRH 1646
+ P RS SP N C P+R S SE + + QRS G SQ
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRE-RSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
Query: 1647 HSPSERSHRSPSERSHRSSS---ERRHRSP-SQRSHRGPS-------------ERSHCSP 1689
PS SP ERS SS + + R+P QRS G S RS SP
Sbjct: 1547 VKPSA----SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP 1602
Query: 1690 S-----------------------------ERRHRSPSQRSHRGPSERRHHSPSKRSHRS 1720
RR RS S RGPS S
Sbjct: 1603 EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662
Query: 1721 PARRSHRSPSERSHHSPSERSHHSPSERRHHSPSE---RSHCSPSERSHCSPSERRHRSP 1777
P R+ R S RS P +S P R S E ++ S RS S E R R+P
Sbjct: 1663 PKSRTARRGS-RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP 1721
Query: 1778 SERRHH------SPSEKSHHSPSERSHHSP----SERRRHSP------LERSR-HSLLER 1820
R P+EKS S RS SP + RR SP L+RSR S E+
Sbjct: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781
Query: 1821 SHRSPSERRS--------HRSFERSHRRISERSHSPSEKSHLSPL--ERSRCSPSERRGH 1870
+ + RS R RS R++ R S SP E SR S RRG
Sbjct: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGR 1841
Query: 1871 SSSGKTCHSPSERSHRSPSGMRQGRT--SERSHRSSCERT-----RHSPSEMRP-GRPSG 1922
S + T S RS SP+ ++ R+ S +HR S RT R S S P R
Sbjct: 1842 SRTPPTSRKRS-RSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRS 1900
Query: 1923 RNHCSPSERSRRS 1935
R+ S + R RS
Sbjct: 1901 RSRTSVTRRRSRS 1913
Score = 92.4 bits (228), Expect = 4e-18
Identities = 197/819 (24%), Positives = 298/819 (36%), Gaps = 137/819 (16%)
Query: 1189 IRRSPISPSQRKAKIYTQAS-KSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTK 1247
+ + P++P + ++ KSP S S P+P + R S P+ +
Sbjct: 386 LSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAP 445
Query: 1248 TRAPGHYEFTQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRI--TKRLRKHRKFYT 1305
APG + ++ + P S + S KR K S S P +R+ ++ ++ +
Sbjct: 446 --APGSHR--EISSSPTSKNRSHGRAKRDK------SHSHTPSRRMGRSRSPATAKRGRS 495
Query: 1306 NSRT-TIESPSRELAAHLRRKRIGATQTSTASLKRQ--PKKPSQPKFMQLLFQSLKRAFQ 1362
SRT T SR + RR R + S +R+ + P +P + R+
Sbjct: 496 RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW--------SRSRN 547
Query: 1363 TAHRVIASVGRKPVDGTR-PDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGST 1421
T R + R+ +R P S++ P + R + +R + TP
Sbjct: 548 TQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSR----TPTRR- 602
Query: 1422 IKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKD 1481
+ RS RR S P R T S P+R +
Sbjct: 603 ------------RSRSRTPARRGRSRSRTPARRRSRTRS-------------PVRRRSRS 637
Query: 1482 SSSRSKKNFYRNETSSQESKNLS-TPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHN 1540
S + R+ T ++ ++ S TP R ++R R +P +R+ +
Sbjct: 638 RSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSR----TPARRSGRSRSRTPARRGRS- 692
Query: 1541 HPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSS 1600
R RTPR R+R R RS S QR RS S RKN S
Sbjct: 693 -----RSRTPR--RGRSRSRSLVRRGRSHSRTPQRRG----------RSGSSSERKNKSR 735
Query: 1601 PSERSWRSPSQRNHCSPPERSCHSLSER---GLHSPSQRSHRGPSQRRHHSPS----ERS 1653
S+R RS S PE +S R L SP ++ S RR S S ++
Sbjct: 736 TSQRRSRSNSS------PEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQK 789
Query: 1654 HRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS---PSERRHRSPSQRSHRGPSERRH 1710
++P RS SS+ + +S R P RS S P +++ ++PS++SH S
Sbjct: 790 SQTPPRRSRSGSSQPKAKS------RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH-- 841
Query: 1711 HSPSKRSHRSPARRSHRSPSERSHH-SPSERSHHSPS---ERRHHSPSERSHCSPSERSH 1766
P +S P + S SP +P RS S E + +PS S CS S
Sbjct: 842 --PKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHS-CSGSSPPR 898
Query: 1767 CSPSERRHRSPSERRHHSPSEKSHHSPSERSH---HSPSERR---RHSPLERSRHSLLER 1820
S +SPS P K+ SP +RSH SPS R R +P S
Sbjct: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
Query: 1821 SHRSPSERRSHRSFERSHRRISERSHSPSEKSH---LSPLERSRCSPSERRGHSSSGKTC 1877
R SH ++ + +P +SH +SP + + G S SG
Sbjct: 959 VESRLLPRYSHSGSSSPDTKV--KPETPPRQSHSGSISPYPKVKAQTPP--GPSLSGSKS 1014
Query: 1878 HSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPL 1937
P E+S S G S + S S + + G++ SP RS S
Sbjct: 1015 PCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSS- 1073
Query: 1938 KEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
P R SHS S +L + +PK G+
Sbjct: 1074 --------PEVRQSHSES------PSLQSKSQTSPKGGR 1098
Score = 92.4 bits (228), Expect = 4e-18
Identities = 155/548 (28%), Positives = 207/548 (37%), Gaps = 63/548 (11%)
Query: 1431 GTVQCRSAQQPRRAYSFQPRPL-RLPK----------PTDSQSGIAFQTASVGQPLRTV- 1478
G +C S+ +P+ A PRP R P P +SG +SV Q +TV
Sbjct: 1476 GRSECDSSPEPK-ALPQTPRPRSRSPSSPELNNKCLTPQRERSG---SESSVDQ--KTVA 1529
Query: 1479 -----QKDSSSRSKKNFYRNETSSQE-SKNLSTPGTRVQARGRILPGSPVKRTWHRHLKD 1532
Q+ S S++ + S QE S++ S+P ++ + R + S + K
Sbjct: 1530 RTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589
Query: 1533 KLTHKEHNHPSFYRERT-PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC 1591
+L+ + S + PR + S ++P+ R+ L RR S S
Sbjct: 1590 RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRA----LPRRSRSGSSSKGR 1645
Query: 1592 SPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRG-PSQRRHHSPS 1650
PS + SS +E S P + RS + P +RS R P R S
Sbjct: 1646 GPSPEGSSS-TESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLS 1704
Query: 1651 ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPS-------QRSHR 1703
RS + S RS + RHR S P+E+S S RR RS S R R
Sbjct: 1705 RRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSR---SSRRRRSASSPRTKTTSRRGR 1761
Query: 1704 GPSER-----RHHSPSKRSHRSPARRSHRSPSERSHHSPSERSH-HSPSERRHHSPSERS 1757
PS + R S S+R RR RS S +S +RS S RR S
Sbjct: 1762 SPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYH 1821
Query: 1758 HCSPSERSHCSPSERRHRSPSERRHHS-PSEKSHHSPS----ERSHHSPSERRR---HSP 1809
SP+ + S RR R S S +S SP+ RS SP+ RR +P
Sbjct: 1822 SRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881
Query: 1810 LERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRG 1869
L R S RS SP RR RS RR S SP + RSR P RR
Sbjct: 1882 LISRRRS---RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR----SRSRTPPVTRRR 1934
Query: 1870 HSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPS 1929
S T S RS P R+ R+ R+R SP R R
Sbjct: 1935 SRSRTPTTRRRS-RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRR 1993
Query: 1930 ERSRRSPL 1937
RSR SP+
Sbjct: 1994 SRSRTSPV 2001
Score = 86.7 bits (213), Expect = 2e-16
Identities = 125/445 (28%), Positives = 178/445 (40%), Gaps = 62/445 (13%)
Query: 1550 PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSP 1609
P P R + S R+ +P ++ ++ +R S S SP R+ S ++ RS
Sbjct: 167 PPKPYSLVRESSSSRSP-TPKQKKKKKKKDRGRRSESS----SPRRERKKSSKKKKHRSE 221
Query: 1610 SQ---RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSH---R 1663
S+ R H SP +S ++ S+ + P RR H + S S+ S R
Sbjct: 222 SESKKRKHRSPTPKSKRKSKDK-KRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR 280
Query: 1664 SSSERRH------RSPSQRS-HRGPSERSHCSPSERRHRSPS--QRSHRGPSERRHHSPS 1714
S++ + H RSPS S RG + P + PS + + + PS
Sbjct: 281 SAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDK 340
Query: 1715 KRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSP----S 1770
+ +S A R SP ERS P + RH + +P + +P S
Sbjct: 341 DKKEKS-ATRPSPSP-ERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEAS 398
Query: 1771 ERRHRSPSERRHHSPSEKSHHSPSERSHHSPS----ERRRHSPLERSRHSLLERSHRSPS 1826
R RSP + SP + S SE S SP R S E + + SHR S
Sbjct: 399 PTRDRSPPK----SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454
Query: 1827 ERRSHRSFERSH---RRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSER 1883
S S RSH +R SH+PS + + RSR + +RG S S +P++R
Sbjct: 455 S--SPTSKNRSHGRAKRDKSHSHTPSRR-----MGRSRSPATAKRGRSRS----RTPTKR 503
Query: 1884 SH---RSPSGMRQGRTSERSHRS-SCERTRHSPSEMRPGRPSGRN-----HCSPSERSR- 1933
H RSP R+ R+++R RS S +R S S RPG RN + R R
Sbjct: 504 GHSRSRSPQ-WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRS 562
Query: 1934 --RSPLKEGLKYSFPGERPSHSLSR 1956
RSP G S R S SR
Sbjct: 563 HSRSPATRGRSRSRTPARRGRSRSR 587
Score = 82.0 bits (201), Expect = 5e-15
Identities = 208/845 (24%), Positives = 308/845 (36%), Gaps = 135/845 (15%)
Query: 1174 KRSQISKYRERDRPVIRRSPISPSQRKAKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIR 1233
+++ +S + PV+ P +PS+ ++ S S+ +++ G ++P+ R
Sbjct: 1392 EKAGMSSNQSISSPVLDAVPRTPSRERS--------SSASSPEMKDGLPRTPSR-----R 1438
Query: 1234 RGQRSRPDLVEKTKT--------RAPGHYEFTQVHNLPESDSESTQNEKRAKVRTKKTSD 1285
S P L + + T +PG + + + S+ +S+ K + S
Sbjct: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSR 1498
Query: 1286 SKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQTSTASLKRQPKKPS 1345
S + K L R+ + S ++++ + +R R G++Q P++ S
Sbjct: 1499 SPSSPELNNKCLTPQRE-RSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERS 1557
Query: 1346 QPKFMQLLFQSLKRAFQTAHRVIASVGRKP-VDG-TRPDNLWASKNYYPKQNARDYCLPS 1403
+ K +T R + G P VD +R + P+ + P
Sbjct: 1558 ESDSSP----DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPR 1613
Query: 1404 SIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSG 1463
+ S + PA + + G+ P + S + P PK ++ G
Sbjct: 1614 AQSGSDSSPEPKAPAPRALPRRSR--SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRG 1671
Query: 1464 IAFQTASVGQPL---RTVQKDSSSRSKKNFYRNETSSQESKNLST-PGTRVQA--RGRIL 1517
+ S +P RT + SSRS R S+ S++ S+ P TR + R R
Sbjct: 1672 ----SRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS 1727
Query: 1518 PG-----------SPVKRTWHRHLKDKLTHKEHNHPS-------FYRERTPRGPSERTRH 1559
P S +R + K T + PS R R+ R + TR
Sbjct: 1728 PSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
Query: 1560 NPSWRNHRSPSERSQRSS----LERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHC 1615
+ +S S R QRS + RR S SP+R+ S S R R S+
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR---- 1843
Query: 1616 SPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSH-RSSSERRHRSPS 1674
+PP S S R +P +RS S H R+ RS R+S R RS S
Sbjct: 1844 TPPTSRKRSRS-RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS 1902
Query: 1675 QRSHRGPSERSHCSP-SERRHRSPSQRSHRGPSERRHHSPSKRSH-RSPARRSHRSPSE- 1731
+ S RS SP S RR RS + R S R + +RS R+P RS S
Sbjct: 1903 RTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRT 1962
Query: 1732 --------RSHHSP----SERSHHSPSERRHHSPSERSHCSP----SERSHCSPSERRH- 1774
RS SP RS SP RR RS SP RS SP RR
Sbjct: 1963 PPVTRRRSRSRTSPITRRRSRSRTSPVTRRR----SRSRTSPVTRRRSRSRTSPVTRRRS 2018
Query: 1775 --RSPSERRHHSPSEKSHHSPSERSH-HSPSERRRHSPLERSRHSLLERSHRSPSERRSH 1831
R+P R S S ++ P +RS SP RR S R+P R
Sbjct: 2019 RSRTPPAIRRRSRS-RTPLLPRKRSRSRSPLAIRRRS------------RSRTPRTARGK 2065
Query: 1832 RSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGM 1891
RS RS I RS S S S ++ P+ R+H SG
Sbjct: 2066 RSLTRSPPAIRRRSASGSS--------------------SDRSRSATPPATRNH---SGS 2102
Query: 1892 RQGRTSERSHRSSC-ERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKE--GLKYSFPGE 1948
R + S R SC R SP+ + R G S R+ S L++ G PG
Sbjct: 2103 RTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGP 2162
Query: 1949 R-PSH 1952
R P H
Sbjct: 2163 RIPDH 2167
Score = 79.3 bits (194), Expect = 3e-14
Identities = 124/435 (28%), Positives = 163/435 (37%), Gaps = 90/435 (20%)
Query: 1567 RSPSER--SQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHS 1624
R+PS S SS E + P +PSR++ RS SP R+ P R S
Sbjct: 1412 RTPSRERSSSASSPEMKDGLPR-----TPSRRS------RSGSSPGLRDGSGTPSRHSLS 1460
Query: 1625 LSERGLHSPSQRSHRGPSQ--------RRHHSPSERSHRSPS--ERSHRSSSERRHRSPS 1674
S G+ + RG S+ +P RS RSPS E +++ + +R RS S
Sbjct: 1461 GSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRS-RSPSSPELNNKCLTPQRERSGS 1519
Query: 1675 ---------------QRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHR 1719
QRS G S+ PS SP +RS S SK R
Sbjct: 1520 ESSVDQKTVARTPLGQRSRSGSSQELDVKPSA----SPQERSESDSSP-----DSKAKTR 1570
Query: 1720 SPARRSHRSPSE-----RSHHSPSE-RSHHSPSERRHHSPSER----SHCSPSERSHCSP 1769
+P R+ RS S +S SP RS SP + + R S SP ++
Sbjct: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR 1630
Query: 1770 S-ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERR-----RHSPLERSRHSLLERSHR 1823
+ RR RS S + PS + S H P R R SP +++ R
Sbjct: 1631 ALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKS-------R 1683
Query: 1824 SPSERRSHRSFERSHR--RISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPS 1881
+P RRS RS R R+S RS S S SP RSR P RR S S
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSRRSRSASS----SPETRSRTPPRHRRSPSVS-------- 1731
Query: 1882 ERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGL 1941
SP + R+S R +S RT+ + R P R RSRR +
Sbjct: 1732 -----SPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTR 1786
Query: 1942 KYSFPGERPSHSLSR 1956
+ G S S R
Sbjct: 1787 RRDRSGSSQSTSRRR 1801
Score = 74.3 bits (181), Expect = 1e-12
Identities = 108/431 (25%), Positives = 160/431 (37%), Gaps = 89/431 (20%)
Query: 1618 PERSCHSLSERGLHSPSQRSH-RGPSQRRHHSPSERSHRSPSERSHRS--SSERRHRSPS 1674
P+R + P S R S R +P ++ + +R RS SS RR R S
Sbjct: 153 PQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKS 212
Query: 1675 QRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERS- 1733
+ + RS +R+HRSP+ +S R +++ + +RR+HRS S S
Sbjct: 213 SKKKK---HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA 269
Query: 1734 ---------HHSPSERSHHSPSERRHHSP------------SERSHCSPSERSHCSPSER 1772
S + ++H + R SP SE S S + +
Sbjct: 270 SSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATK 329
Query: 1773 RHRSPSERRHHSPSEKSHHSPS---ERSHHSP---------SERRRHSPLERSRHSLLER 1820
+ SP E + EKS PS ERS P +ER SP + L +
Sbjct: 330 QPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQE 389
Query: 1821 SHRSPSER--RSHRSFERSHRRISERSHSPSEKSHLSPLERSR---CSP----------- 1864
PSE RS +S ++ + S S S P + SR SP
Sbjct: 390 PVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGS 449
Query: 1865 ---------SERRGHSSSGKT---CHSPSER--SHRSPSGMRQGRTSERS------HRSS 1904
S+ R H + + H+PS R RSP+ ++GR+ R+ RS
Sbjct: 450 HREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSR 509
Query: 1905 CERTRHSPSEMRPGRPSGRNHCSPSERSR-RSPLKEGLKYSFPGERPSHSLSRDFKNQTT 1963
+ R S S R GR SP R R RSP + PG S + R ++++
Sbjct: 510 SPQWRRSRSAQRWGRSR-----SPQRRGRSRSPQR-------PGWSRSRNTQRRGRSRSA 557
Query: 1964 LLGTTHKNPKA 1974
G +H A
Sbjct: 558 RRGRSHSRSPA 568
Score = 68.6 bits (166), Expect = 6e-11
Identities = 70/236 (29%), Positives = 88/236 (37%), Gaps = 10/236 (4%)
Query: 1629 GLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS 1688
G PS + P++ R S S S S S S SSS S G S
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Query: 1689 PSERRHRSPSQRSHRGPSERR--HHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPS 1746
+ +R SP+ E R +P+KR RS + S S S S S S S S S
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633
Query: 1747 ERRHHSPSERSHCS------PSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERS-HH 1799
S S S S P ++ P+ + P ERR SP + RS +
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
Query: 1800 SPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLS 1855
SP ERRR SP R S R + S SH+R E + SP H S
Sbjct: 2694 SPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRE-TPSPRPMRHRS 2748
Score = 64.7 bits (156), Expect = 9e-10
Identities = 212/932 (22%), Positives = 322/932 (34%), Gaps = 197/932 (21%)
Query: 1154 RTPEGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRKAKIYTQASKSP-- 1211
RTP G R R R RS + + R R R RRS S S+ A+ S++P
Sbjct: 607 RTPARRGRSRSRTPARRRSRTRSPVRR-RSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
Query: 1212 -----TSTIDLQSGPSQSPAPVQVYIRRGQ-RSRPDLVEKTKTRA-----PGHYEFTQVH 1260
+ T +SG S+S P RRG+ RSR ++++R+ H Q
Sbjct: 666 RGRSRSRTPARRSGRSRSRTPA----RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRR 721
Query: 1261 NLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRL-------RKHRKFYTNSRTTIES 1313
S SE + ++ R++ S + RI+ R R K + R ++
Sbjct: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSG 781
Query: 1314 ----PSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIA 1369
P ++ RR R G++Q S R P + S+ Q K + +H +
Sbjct: 782 SSPCPKQKSQTPPRRSRSGSSQPKAKS--RTPPRRSRSSSSPPPKQKSKTPSRQSHSS-S 838
Query: 1370 SVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTP----AGSTIKQE 1425
S K GT P + P+ N + S+ +RS + +P T +
Sbjct: 839 SPHPKVKSGTPPRQGSITS---PQANEQ------SVTPQRRSCFESSPDPELKSRTPSRH 889
Query: 1426 DILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSR 1485
+ +S+ PR++ S P K S + +S P R + + R
Sbjct: 890 SCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR 949
Query: 1486 SKKNFYRNETSSQESKNL--------STPGTRVQARGRILPGSPVKRTWHRHLKDKLTHK 1537
S+ + S+ ES+ L S+P T+V+ P +P +++ +
Sbjct: 950 SRSV---SPCSNVESRLLPRYSHSGSSSPDTKVK------PETPPRQSHSGSISP----- 995
Query: 1538 EHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKN 1597
+P + +TP GPS +P P E+S+ S ++ P S C+ K+
Sbjct: 996 ---YPKV-KAQTPPGPSLSGSKSPC------PQEKSKDSLVQS---CPGSLSLCA-GVKS 1041
Query: 1598 HSSPSE------------RSWRSPSQRNHCSPPE-RSCHSLSERGLHSPSQRSHRGPSQR 1644
+ P E +S SP R+ S PE R HS S L S SQ S +G R
Sbjct: 1042 STPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP-SLQSKSQTSPKGGRSR 1100
Query: 1645 RHHSPSERSHRSP--SERSHRSSSE--RRHRSPSQRSHRGPS--------------ERSH 1686
+E + RSP +R S+S + SP Q + S R
Sbjct: 1101 SSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLE 1160
Query: 1687 CSPSERRHRSPSQRSHRG--PSERRHHSP------------SKRSHRSPARR---SHRSP 1729
+ S+ + P Q P ++ SP K + R+P R + SP
Sbjct: 1161 TAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSP 1220
Query: 1730 SERSHHSP-------------SERSHHSPSERRHHSPSERSHCSPSERSHCSPSERR--- 1773
+ +S E+S + H SE S S E R
Sbjct: 1221 ETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAV 1280
Query: 1774 ----HRSPSERR----------------HHSPSEK--SHHSPSERSHHSPSERRRHSPL- 1810
+S S+ H SP K S+ E S SP E R PL
Sbjct: 1281 SLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLG 1340
Query: 1811 ------------ERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSP-- 1856
E L + PS +S S SE S EK+ +S
Sbjct: 1341 TEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQ 1400
Query: 1857 ------LERSRCSPSERRGHSSSGKTC-----HSPSERSHRSPS-GMRQGRTSERSHRSS 1904
L+ +PS R S+S +PS RS S G+R G + H S
Sbjct: 1401 SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLS 1460
Query: 1905 CERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936
P R GR+ C S + P
Sbjct: 1461 GSSPGMKDIPRTPSR--GRSECDSSPEPKALP 1490
Score = 59.3 bits (142), Expect = 4e-08
Identities = 80/289 (27%), Positives = 108/289 (37%), Gaps = 41/289 (14%)
Query: 1452 LRLPKPTDSQSGIAFQTASVG----------QPLRTVQKDSSSRSKKNFYRNETSSQESK 1501
L +P P S + AS G QP + ++ SSS S + + +SS S
Sbjct: 2494 LSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKE-RRSSSSSSSSSSSSSSSSSSSSS 2552
Query: 1502 NLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNP 1561
+ S+ + + G LP P ++ K P TP P E R
Sbjct: 2553 SSSSGSSSSDSEGSSLPVQP-----------EVALKRVPSP------TP-APKEAVREGR 2594
Query: 1562 SWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERS 1621
+P++R +RSS S S S S S + SS S S S S + S P +
Sbjct: 2595 P--PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652
Query: 1622 CHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGP 1681
+ L P+ P +RR SP + RS S R R Q S R
Sbjct: 2653 --KPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRD- 2709
Query: 1682 SERSHCSPSERRHRSPSQRSHRGPS-ERRHHSPSKRSHRSPARRSHRSP 1729
S SER R + R PS +RR +PS R R RS RSP
Sbjct: 2710 ---QQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR---HRSSRSP 2752
Score = 57.4 bits (137), Expect = 1e-07
Identities = 85/303 (28%), Positives = 109/303 (35%), Gaps = 44/303 (14%)
Query: 1652 RSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHH 1711
RS PS S + R SPS R + PS+ S P++ + RSP PS
Sbjct: 2406 RSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ-SLLPPAQDQPRSPV------PSAFSDQ 2458
Query: 1712 SPSKRSHRSPARRSHRSPSERSHHSPSERSHHS-----PSERRHHS-----PSERSHCSP 1761
S + +P S S + S H+ P+ HS P+ P
Sbjct: 2459 SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQP 2518
Query: 1762 SERSHCSPS-ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLER 1820
S + P+ ERR S S S S S S S S S S S L L+R
Sbjct: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578
Query: 1821 SHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSP 1880
PS + + R R P E + P +R R S S SSS + S
Sbjct: 2579 V---PSPTPAPKEAVREGR--------PPEPT---PAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 1881 SERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPG-----RPSGRNHCSPSERSRRS 1935
S S S S S S SS + SPS +PG +P+ P ER RS
Sbjct: 2625 SSSSSSSSS-------SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS 2677
Query: 1936 PLK 1938
P K
Sbjct: 2678 PRK 2680
Score = 55.1 bits (131), Expect = 7e-07
Identities = 111/465 (23%), Positives = 179/465 (38%), Gaps = 55/465 (11%)
Query: 1171 RIGKRSQIS-KYRERDRPVIRRSPISPSQRKAKIYTQASKSPTSTIDLQS--------GP 1221
R G RS K + R P R S SP + ++ S+S +S+ + +S P
Sbjct: 1669 RRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSP 1728
Query: 1222 S-QSPAPVQVYIRRGQRSRPDLVEKTKTRAP-GHYEFTQVHNLPESDSESTQNEKRAKVR 1279
S SP P + R +R R +TKT + G + L S S S + + R R
Sbjct: 1729 SVSSPEPAEKS-RSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRR 1787
Query: 1280 TKKTSDSKYPMKRITK---RLRKHRKFYTNSRTTIESPSRELAAHLR-RKRIGATQTSTA 1335
++ S+ +R + R R R+ S SP+R+ ++ R+R G ++T
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPT 1847
Query: 1336 SLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASKNYYPKQN 1395
S KR + S + + S RA HR S R P+ R S +
Sbjct: 1848 SRKRSRSRTSPAPWKR----SRSRASPATHR--RSRSRTPLISRRRSRSRTSPVSRRRSR 1901
Query: 1396 ARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQP---RRAYSFQP--- 1449
+R +S+ R +RS + +P + RS P RR+ S P
Sbjct: 1902 SR-----TSVTR-RRSRSRASPVSRR------------RSRSRTPPVTRRRSRSRTPTTR 1943
Query: 1450 RPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTR 1509
R R P ++ +T V + + +R + + + + S++ ++P TR
Sbjct: 1944 RRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTR 2003
Query: 1510 VQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSP 1569
++R R SPV R R + R RTP P +R+R R
Sbjct: 2004 RRSRSRT---SPVTRRRSRSRTPPAIRRRS------RSRTPLLPRKRSRSRSPLAIRRRS 2054
Query: 1570 SERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNH 1614
R+ R++ +R + S + S SS RS P+ RNH
Sbjct: 2055 RSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
Score = 54.3 bits (129), Expect = 1e-06
Identities = 75/259 (28%), Positives = 95/259 (36%), Gaps = 30/259 (11%)
Query: 1574 QRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSP 1633
Q S+L + +RS S S + SS S S S S + S + SL + P
Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQ----P 2572
Query: 1634 SQRSHRGPSQRRHHSPSERSHR----SPSERSHRSSSERRHRSPSQRSHRGPSERSHCSP 1689
R PS + R R +P++R RSSS S S S S S S
Sbjct: 2573 EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSS 2632
Query: 1690 SERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR 1749
S S S S S S S P ++ P+ P ER SP +
Sbjct: 2633 SSSSSSSSSSSS----------SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPI 2682
Query: 1750 HHSPSERS-HCSPSERSHCSPSERRHRSPSER-RHHSPSEKSHHSPSERSHHSPS-ERRR 1806
RS SP ER SP PS R + S SE+ SPS +RRR
Sbjct: 2683 DSLRDSRSLSYSPVERRRPSP------QPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRR 2736
Query: 1807 HSPLERSRHSLLERSHRSP 1825
+P S + RS RSP
Sbjct: 2737 ETP---SPRPMRHRSSRSP 2752
Score = 46.2 bits (108), Expect = 3e-04
Identities = 102/444 (22%), Positives = 156/444 (35%), Gaps = 84/444 (18%)
Query: 1205 TQASKSPTSTIDLQSGPSQSPA-------PVQVYIRRGQRSRPDLVEKTKTRAPGHYEFT 1257
T A+ +P S + P+ S A P+ Y R R+ P L+++ ++R P
Sbjct: 2357 TAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTP------ 2410
Query: 1258 QVHNLPESDSESTQNEKRAKVRTKKT----SDSKYPMKRITKRLRKHRKFYTNSRTTIES 1313
P + S+S +RA + + S S P + R F SR I
Sbjct: 2411 -----PSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ 2465
Query: 1314 PSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGR 1373
+ A + GA T+T+S S P A H + VG
Sbjct: 2466 TTP--VAGSQSLSSGAVATTTSSAGDHNGMLSVP------------APGVPH---SDVGE 2508
Query: 1374 KPVD-GTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGT 1432
P G + + A+ ++ + SS S+ + + S D G +
Sbjct: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE-GSS 2567
Query: 1433 VQCRSAQQPRRAYSFQPRPL------RLPKPT-------DSQSGIAFQTASVGQPLRTVQ 1479
+ + +R S P P R P+PT S S + ++S +
Sbjct: 2568 LPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSS 2627
Query: 1480 KDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEH 1539
SSS S + + +SS S + + PG + + P SP K
Sbjct: 2628 SSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPK----PASPKKPP-------------- 2669
Query: 1540 NHPSFYRERTPRGPSERTR------HNPSWRNHRS--PSERSQRSSLERRHHSPSQRSHC 1591
P R R+PR P + R ++P R S PS R Q+SS R QR
Sbjct: 2670 --PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDS 2727
Query: 1592 -SPSRK-NHSSPSERSWRSPSQRN 1613
SPS K +PS R R S R+
Sbjct: 2728 RSPSHKRRRETPSPRPMRHRSSRS 2751
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 110 bits (276), Expect = 1e-23
Identities = 170/668 (25%), Positives = 244/668 (36%), Gaps = 98/668 (14%)
Query: 1264 ESDSESTQNEKRAKVRTKKTSDSKYPM-KRITKRLRKHRKFYTNSRTTIESPSRELAAHL 1322
+ + + + EKR + R+ + S+ P +R + +R+ RK R+ SP
Sbjct: 155 DKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERK-----RSHSRSP-------- 201
Query: 1323 RRKRIGATQTSTASLKRQPKKPSQPK-FMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRP 1381
R R + S A K++ K P P+ +++ S++ A T+ + KP P
Sbjct: 202 -RHRTKSRSPSPAPEKKE-KTPELPEPSVKVKEPSVQEATSTSDILKVP---KPEPIPEP 256
Query: 1382 DNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQP 1441
KN K+ ++ P S R K + + + S + R +
Sbjct: 257 KEPSPEKNS-KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPR----------RRHRSR 305
Query: 1442 RRAYS--FQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQE 1499
R+YS +P P R P P P R RS+ R SS
Sbjct: 306 SRSYSPRRRPSPRRRPSPRRRTP-----------PRRMPPPPRHRRSRSPVRRRRRSSAS 354
Query: 1500 SKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSF-YRERTPRGPSERTR 1558
S+ + +R R P P KRT K + + P +R P P +TR
Sbjct: 355 LSGSSSSSS--SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412
Query: 1559 HNPS------WRNHRSPSERSQRSSLERRHHSPSQRSHCSPS---RKNHSSPSE------ 1603
H+P+ R R + S +H +R SP+ RK S SE
Sbjct: 413 HSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472
Query: 1604 -------RSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRS 1656
+ R ++N S + S SE S + +RR HSPS + S
Sbjct: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS 532
Query: 1657 PSERSHRSSSE-RRHRSPSQ---RSHRGPS-------ERSHCSPSERRHRSPSQRSHRGP 1705
P +R +S RR RSPS R R PS R+ P RR SP R R P
Sbjct: 533 PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR-RRSP 591
Query: 1706 SERRHHSPSKR--SHRSPARRSHRSPSERSHHSPSERSHHSPSERRH--HSPSERSHCSP 1761
S RR+ P +R S P +R SP P R+ SP +R HSP + SP
Sbjct: 592 SPRRYSPPIQRRYSPSPPPKRRTASPPP----PPKRRASPSPPPKRRVSHSPPPKQRSSP 647
Query: 1762 SERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERS 1821
+ +HR S S S + SP HSPS R R S + +
Sbjct: 648 VTKRRSPSLSSKHRKGSSP---SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
Query: 1822 HRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPS 1881
SP R+S R RR+S K SP SP R SSS SP
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP------SPQSVRRVSSSRSVSGSPE 758
Query: 1882 ERSHRSPS 1889
+ + P+
Sbjct: 759 PAAKKPPA 766
Score = 109 bits (273), Expect = 2e-23
Identities = 150/593 (25%), Positives = 218/593 (36%), Gaps = 101/593 (17%)
Query: 1437 SAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETS 1496
S ++ R+ S + R R P P S P+R +K S SRS ++ ++ +
Sbjct: 162 SREKRERSRSPRRRKSRSPSPRRRSS-----------PVRRERKRSHSRSPRHRTKSRSP 210
Query: 1497 S------QESKNLSTPGTRVQA----------------RGRILPG----SPVKRTWHRHL 1530
S +++ L P +V+ + +P SP K +
Sbjct: 211 SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKE 270
Query: 1531 KDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSER--SQRSSLERRHHSPSQR 1588
K+K + + R PS H R HRS S +R RR SP +R
Sbjct: 271 KEKTRPRSRSRSKSRSRTRSRSPS----HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
Query: 1589 SHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQ--RRH 1646
+ P R+ P R RSP +R RS SLS S S RS P + +R
Sbjct: 327 T---PPRRMPPPPRHRRSRSPVRRRR-----RSSASLSGSSSSSSSSRSRSPPKKPPKRT 378
Query: 1647 HSPSERSHR-----SPSERSHRSSS------ERRHRSPSQRSHRGPSERSHCSPSERRHR 1695
SP ++ R SP R HR S + RH Q+S+R R SP
Sbjct: 379 SSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT--- 435
Query: 1696 SPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSE 1755
S H+G +R SP+ + + S + + S + + S S+
Sbjct: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
Query: 1756 RSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHH-SPSERRRHSPLERSR 1814
S SE S ++ RR HSPS + SP +R SP RRR SP
Sbjct: 496 SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPT 555
Query: 1815 HSLLERSHRSPSERRSHRSFERSHRRIS--ERSHSPSEKSHLSPLERSRCSPS------- 1865
S P RR + R S R SPS + + P++R R SPS
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQR-RYSPSPPPKRRT 614
Query: 1866 -------ERRGHSS---SGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEM 1915
+RR S + HSP + SP R+ + HR +R S E
Sbjct: 615 ASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR-STREA 673
Query: 1916 RPGRPSGRNHCSPSERSRRS-----PLKEGLKYS-------FPGERPSHSLSR 1956
R +P+ R+ SP R+ ++ P++ G S P RP +SR
Sbjct: 674 RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
Score = 107 bits (267), Expect = 1e-22
Identities = 198/807 (24%), Positives = 305/807 (37%), Gaps = 126/807 (15%)
Query: 1144 LLIYPQLHLVRTPEGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRKAKI 1203
LL+ Q ++ P E++ + R ++ +++ +++D +R + K
Sbjct: 108 LLLSAQENIAGIPSAFLELKKE-EIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREK- 165
Query: 1204 YTQASKSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLP 1263
+ S+SP P + +PV+ +R P K+++ +P + + LP
Sbjct: 166 -RERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
Query: 1264 E--------SDSESTQNEKRAKV-------RTKKTSDSKYPMKRITK---RLRKHRKFYT 1305
E S E+T KV K+ S K K K R R + +
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
Query: 1306 NSRTTIESPSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAH 1365
SRT SPS H R +R +++ + S +R+P +P + ++ R
Sbjct: 285 RSRTRSRSPS-----HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR---RTPPRRMPPPP 336
Query: 1366 RVIASVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQE 1425
R S R PV R + S + ++R P K KR++ +P T +
Sbjct: 337 RHRRS--RSPVRRRRRSSASLSGSSSSSSSSRSRSPPK--KPPKRTS---SPPRKTRRLS 389
Query: 1426 DILWGGTVQCRSAQQPRRAYSFQPRPLRLPK----PTDSQSGIAFQTASVGQPLRTVQKD 1481
SA PRR + P PK PT QS ++ P RT K
Sbjct: 390 P----------SASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKV 439
Query: 1482 SSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNH 1541
+ + T +ES + + +V+ L S + D + +
Sbjct: 440 TKHKG--------TEKRESPSPAPKPRKVE-----LSESEEDKGGKMAAADSVQQRRQ-- 484
Query: 1542 PSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLE------RRHHSPSQRSHCSP-S 1594
YR + + S+ S + S ER +RS ++ RR HSPS+ + SP
Sbjct: 485 ---YRRQNQQSSSD------SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRK 535
Query: 1595 RKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPS---QRRHHSPSE 1651
R+ +SP R RSPS PP R S S +P R R P+ +RR SP
Sbjct: 536 RQKETSPRGRRRRSPS-----PPPTRRRRSPSP----APPPRRRRTPTPPPRRRTPSPPP 586
Query: 1652 RSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS--PSERRHRSPSQRSHRGPSERR 1709
R RSPS R + +RR+ SPS P +R S P +R SPS P R
Sbjct: 587 R-RRSPSPRRYSPPIQRRY-SPSP-----PPKRRTASPPPPPKRRASPSP----PPKRRV 635
Query: 1710 HHSPSKRSHRSPARRSHRSPSERSHH------SPSERSHHSPSERRHHSPSERSHCSPSE 1763
HSP + SP + RSPS S H S S R SP + HSPS R +
Sbjct: 636 SHSPPPKQRSSPVTK-RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA--PQ 692
Query: 1764 RSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHR 1823
S P RR S S +R SP SPS R P R +P + S +
Sbjct: 693 TSSSPPPVRRGASSSPQRRQSP------SPSTR----PIRRVSRTPEPKKIKKAASPSPQ 742
Query: 1824 SPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSER 1883
S S RS S +++ +P S + SP+ + S SP
Sbjct: 743 SVRRVSSSRSVSGSPEPAAKKPPAPPSPVQ-SQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
Query: 1884 SHRSPSGMRQGRTSERSHRSSCERTRH 1910
S + G ++ + ++ H+ + +H
Sbjct: 802 SDQEGGGKKKKKKKDKKHKKDKKHKKH 828
Score = 107 bits (266), Expect = 2e-22
Identities = 138/474 (29%), Positives = 179/474 (37%), Gaps = 77/474 (16%)
Query: 1531 KDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLER--RHHSPSQR 1588
KDK +E RER+ R P R +PS R SP R ++ S R RH + S+
Sbjct: 151 KDKRDKEEKESSREKRERS-RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRS 209
Query: 1589 SHCSPSRKNHS-----------SPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRS 1637
+P +K + PS + S S PE + E SP + S
Sbjct: 210 PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPE----PIPEPKEPSPEKNS 265
Query: 1638 HRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSP 1697
+ + + S +S S RS S R R + R S R PS RR SP
Sbjct: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR--PSPRRRPSP 323
Query: 1698 SQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHS------PSERRHH 1751
+R+ P R P R RSP RR RS + S S S S S P +R
Sbjct: 324 RRRT---PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380
Query: 1752 SPSERSHCSPSERSHCSPSERRHR-----SPSERRHHSPSEKSHH---------SPSERS 1797
P + SPS SP RRHR +P + HSP+ + + SP S
Sbjct: 381 PPRKTRRLSPS----ASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS 436
Query: 1798 -----HHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSF---ERSHRRISERSHSPS 1849
H +R SP + R L S + + R +RR +++S S S
Sbjct: 437 GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS 496
Query: 1850 EKSHLSPLERSRCS------PSERRGHSSSGKTCHSPSER-SHRSPSGMRQGRTSERSHR 1902
S S ER + S RR HS S SP +R SP G R+ RS
Sbjct: 497 GSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR-----RSPS 551
Query: 1903 SSCERTRHSPSEMRPGR-------PSGRNHCSPSERSRRSPLKEGLKYSFPGER 1949
R R SPS P R P R SP R RRSP +YS P +R
Sbjct: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR-RRSPSPR--RYSPPIQR 602
Score = 85.9 bits (211), Expect = 4e-16
Identities = 96/317 (30%), Positives = 122/317 (38%), Gaps = 46/317 (14%)
Query: 1651 ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRH 1710
++ R E+ R RSP +R R PS R SP R + RS R ++ R
Sbjct: 150 DKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRS 209
Query: 1711 HSPS-KRSHRSPARRSH----RSPSERSHHSPS------------ERSHHSPSERRHHSP 1753
SP+ ++ ++P + PS + S S E SP E+
Sbjct: 210 PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSP-EKNSKKE 268
Query: 1754 SERSHCSPSERSHC-SPSERRHRSPS----ERRHHSPSEKSHHSPSERSHHSPSERRRHS 1808
E+ P RS S S R RSPS RRH S S +SP R PS RRR S
Sbjct: 269 KEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS--YSPRRR----PSPRRRPS 322
Query: 1809 PLERSRHSLL-----ERSHRSPSERRSHRSFE---RSHRRISERSHSPSEKSHLSPLERS 1860
P R+ + R RSP RR S S S RS SP +K P +R+
Sbjct: 323 PRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK----PPKRT 378
Query: 1861 RCSPSERRGHSSSGKTCHSPSERSHR-SPSGMRQGRTSERSHRSSCERTRHSPSEMRPGR 1919
P + R S S SP R HR SP +T RTR S + PGR
Sbjct: 379 SSPPRKTRRLSPSA----SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434
Query: 1920 PSGRNHCSPSERSRRSP 1936
SG+ R SP
Sbjct: 435 TSGKVTKHKGTEKRESP 451
Score = 80.5 bits (197), Expect = 2e-14
Identities = 83/286 (29%), Positives = 108/286 (37%), Gaps = 26/286 (9%)
Query: 1671 RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPS 1730
+ + R E+ R RSP +R R PS RR SP +R + RS R +
Sbjct: 146 KQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRT 205
Query: 1731 ERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSH 1790
+ SP+ E S + PS + S S+ + P P E S
Sbjct: 206 KSRSPSPAPEKKEKTPELPEPSVKVK---EPSVQEATSTSDIL-KVPKPEPIPEPKEPSP 261
Query: 1791 HSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSH---------RRI 1841
S++ R R +SR RS RR HRS RS+ RR
Sbjct: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP 321
Query: 1842 SERSHSPSEKSHLSPLERSRCSPSERRGHSS---SGKTCHSPSERSHRSPSGMRQGRTS- 1897
S R +P + P R SP RR SS SG + S S RS RSP RTS
Sbjct: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS-RSPPKKPPKRTSS 380
Query: 1898 ------ERSHRSSCERTRHSPSEMRPGRPSGRNHCSP--SERSRRS 1935
S +S R RH PS P R+ +P S R+R+S
Sbjct: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKS 426
>gi|118722349 RNA binding motif protein 12B [Homo sapiens]
Length = 1001
Score = 103 bits (256), Expect = 2e-21
Identities = 88/351 (25%), Positives = 113/351 (32%), Gaps = 17/351 (4%)
Query: 1528 RHLKDKLTHKEHNHPSFYRERTP--RGPSERTRHNPS------WRNHRSPSERSQRSSLE 1579
+H + + + P +R + R P E RH+P + R PSE R E
Sbjct: 541 KHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPEDFRRPREEDFRRPSEEDFRRPWE 600
Query: 1580 RRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHR 1639
P + P ++ P E WR P + + P L E P + R
Sbjct: 601 EDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSPTEDFRQLPEEDFRQPPEEDLR 660
Query: 1640 GPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQ 1699
+ P E R P E R + R P + R P P E SP +
Sbjct: 661 WLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDFRRP-------PEEDFRHSPEE 713
Query: 1700 RSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHC 1759
+ P E P + R P R P E P E P E P E
Sbjct: 714 DFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPPPEHFRR 773
Query: 1760 SPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLE 1819
P E P E R P E S E H P E P E RH P E R S E
Sbjct: 774 PPPEHFRRPPQEHFRRPPQEHFRRSREEDFRHPPDEDFRGPPDEDFRHPPDEDFR-SPQE 832
Query: 1820 RSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGH 1870
R PS+ + E R E + + P E R P + R H
Sbjct: 833 EDFRCPSDEDFRQLPEEDLREAPEEDPRLPD-NFRPPGEDFRSPPDDFRSH 882
Score = 95.9 bits (237), Expect = 3e-19
Identities = 105/406 (25%), Positives = 123/406 (30%), Gaps = 41/406 (10%)
Query: 1552 GPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCS-----PSRKNHSSPSERSW 1606
G E RH + QR + H P H S P SP + +
Sbjct: 522 GAFENFRHQLEDLRQLDNFKHPQRDFRQPDRHPPEDFRHSSEDFRFPPEDFRHSPED--F 579
Query: 1607 RSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSS 1666
R P + + P E E P + R P + P E R P E R S
Sbjct: 580 RRPREEDFRRPSEEDFRRPWEEDFRRPPEDDFRHPREEDWRRPLEEDWRRPLEEDFRRSP 639
Query: 1667 ERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSH 1726
R + R P E E R P + R P E P + R P
Sbjct: 640 TEDFRQLPEEDFRQPPEEDLRWLPEEDFRRPPEEDWRRPPEEDFRRPLQGEWRRPPEDDF 699
Query: 1727 RSPSERS-HHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSP 1785
R P E HSP E SP E P E P E P E R P E P
Sbjct: 700 RRPPEEDFRHSPEEDFRQSPQEHFRRPPQEHFRRPPPEHFRRPPPEHFRRPPPEHFRRPP 759
Query: 1786 SEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERS 1845
E P E P E R P E R P + RS E R
Sbjct: 760 PEHFRRPPPEHFRRPPPEHFRRPPQEH---------FRRPPQEHFRRSREEDFR------ 804
Query: 1846 HSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSC 1905
H P E P E R P E SP E R PS + E R +
Sbjct: 805 HPPDEDFRGPPDEDFRHPPDE---------DFRSPQEEDFRCPSDEDFRQLPEEDLREAP 855
Query: 1906 ERTRHSPSEMRPGRPSGRNHCSPSE--RSRRSPLK----EGLKYSF 1945
E P RP G + SP + RS R + EG K+ F
Sbjct: 856 EEDPRLPDNF---RPPGEDFRSPPDDFRSHRPFVNFGRPEGGKFDF 898
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 101 bits (251), Expect = 8e-21
Identities = 109/489 (22%), Positives = 178/489 (36%), Gaps = 47/489 (9%)
Query: 1450 RPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTR 1509
RP P G A + A R QK+ R +K ET + + R
Sbjct: 30 RPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR------R 83
Query: 1510 VQARGRILPGSPVKRTWHRHL-KDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRS 1568
+ R R KR HR +D+ +E RER + ER R R
Sbjct: 84 EKDRHR-------KRDRHRERQRDREKERERQTD---RERDRQREKERNRQKERERETER 133
Query: 1569 PSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSER 1628
ER + +R+ +R + K ++R + ++RN ER + R
Sbjct: 134 EGERGR----DRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 1629 GLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS 1688
QR ++ RH SER ER + +ER+ ++ +R + +ER
Sbjct: 190 --ERERQREKENKTEDRH---SERGRERERERETETETERKRQTDRERDRQRKTEREREK 244
Query: 1689 PSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSER 1748
+ER R+ + + R R + R R ++ +R + +R ER
Sbjct: 245 QAERE-RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRER 303
Query: 1749 RHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHS 1808
+ ER ER + ER E+ + +R +R+R +
Sbjct: 304 QRERERER--------------ERNRKRERERERERERERQRETERDREKERERKRKRQT 349
Query: 1809 PLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERR 1868
++R R+ R R +ER R ER + ER ++ ER R + +R
Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRD 409
Query: 1869 GHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRN--HC 1926
G + K E+ S G +GR ER + ER R ++ + GR R+ +
Sbjct: 410 GQRETEK--QREREKDRESERGRERGR--EREKQKGRERDRERQTDRQAGRQRKRSTLYV 465
Query: 1927 SPSERSRRS 1935
+P R+ RS
Sbjct: 466 NPPPRTARS 474
Score = 73.6 bits (179), Expect = 2e-12
Identities = 70/318 (22%), Positives = 106/318 (33%), Gaps = 14/318 (4%)
Query: 1644 RRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPS---ERSHCSPSERRHRSPSQR 1700
R + ER R ++ R + +R R + HR ER ER ++ +R
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 1701 SHRGPSERRHHSPSKRSHRSPARRSH------RSPSERSHHSPSERSHHSPSERRHHSPS 1754
+ ER +R R + ER + ER + ER+ +
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 1755 ERSHCSPSERSHCSPSER-RHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERS 1813
R E++ ER R R + SE+ ER + +ER+R + ER
Sbjct: 174 NRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 1814 RHSLLERSHRSPSERR--SHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHS 1871
R ER +ER S R ER R ER ER R + +R+ +
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK--ERERQTDRKRQRRT 291
Query: 1872 SSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSER 1931
+ ER + R ER ER R +E + R +E
Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM 351
Query: 1932 SRRSPLKEGLKYSFPGER 1949
R + G + ER
Sbjct: 352 DRERNRQTGREGRRQAER 369
Score = 64.3 bits (155), Expect = 1e-09
Identities = 70/291 (24%), Positives = 104/291 (35%), Gaps = 33/291 (11%)
Query: 1649 PSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSER 1708
P + S R P + S RR + + G +R ER R +++ R +
Sbjct: 23 PLDFSRRRPGSQE---SPRRRGLGQAHKDADG-DDRERNRQKERERRREKRQTERETDRK 78
Query: 1709 RHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCS 1768
R K HR R HR ER ER + ER ER+ ER
Sbjct: 79 RERRREKDRHRK--RDRHR---ERQRDREKERERQTDRERDRQREKERNRQKERERE--- 130
Query: 1769 PSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSER 1828
+ER +R+ E+ ER + ER R + ER R + ER+ + ER
Sbjct: 131 -TEREGERGRDRQTDGQRER------ERQRDAEKERERQTDRERQRQT--ERNRQKERER 181
Query: 1829 RSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSP 1888
+R R R E+ + ++ ER R ER + + + + ER +
Sbjct: 182 EKNRQERRERERQREKENKTEDRHS----ERGRERERERETETETERKRQTDRERDRQ-- 235
Query: 1889 SGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKE 1939
R +ER ER R S E + R +R RR +E
Sbjct: 236 ------RKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERE 280
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 100 bits (250), Expect = 1e-20
Identities = 93/244 (38%), Positives = 115/244 (47%), Gaps = 22/244 (9%)
Query: 1620 RSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHR 1679
RS S+ H +R+ S+ R S +SHRS + RS S RR RS RS
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRS--RSRSRRRRRSSRSRSK- 1879
Query: 1680 GPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSH-HSPS 1738
S E+R RSP RS ER+ S R +R R R+PS RS H+PS
Sbjct: 1880 --SRGRRSVSKEKRKRSPKHRSKS--RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935
Query: 1739 ERSHHSPSERRHH---SPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSE 1795
R RR SPS RS +PS RS +PS RR R+PS RR +PS +S +PS
Sbjct: 1936 RRRRSRSVGRRRSFSISPSRRSR-TPSRRSR-TPS-RRSRTPS-RRSRTPSRRS-RTPSR 1990
Query: 1796 RSHHSPSERRRHSPLERSRHSLLE----RSHRSPSERRSHRS-FERSHRRISERSHSPSE 1850
RS +PS RRR + R R + R R+P RR RS R R SER SP
Sbjct: 1991 RS-RTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Query: 1851 KSHL 1854
+ L
Sbjct: 2050 LTDL 2053
Score = 93.2 bits (230), Expect = 2e-18
Identities = 106/307 (34%), Positives = 135/307 (43%), Gaps = 41/307 (13%)
Query: 1547 ERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSW 1606
ER SE + + E+S+++ + +R SR S SE
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKS 1836
Query: 1607 RSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS-S 1665
R + + +RS S S R SQ R S+RR S RS R RS S
Sbjct: 1837 RKRTSESRSRARKRSSKSKSHR-----SQTRSRSRSRRRRRSSRSRS----KSRGRRSVS 1887
Query: 1666 SERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSER-RHHSPSKRSHRSPARR 1724
E+R RSP RS ER S R +R + R PS R R H+PS+R RR
Sbjct: 1888 KEKRKRSPKHRSKS--RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR------RR 1939
Query: 1725 SHRSPSERSHH-SPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHH 1783
S RS SPS RS +PS RR +PS RS +PS RR R+PS RR
Sbjct: 1940 SRSVGRRRSFSISPSRRSR-TPS-RRSRTPSRRSR-TPS---------RRSRTPS-RRSR 1986
Query: 1784 SPSEKSHHSPSERSHHSPSERRRH---SP--LERSRHSLLERSHRSPSERRSHRSFE--R 1836
+PS +S +PS R RRR SP L RSR L R RSP R+ RS E R
Sbjct: 1987 TPSRRS-RTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGR 2045
Query: 1837 SHRRISE 1843
S +R+++
Sbjct: 2046 SPKRLTD 2052
Score = 85.5 bits (210), Expect = 5e-16
Identities = 94/257 (36%), Positives = 115/257 (44%), Gaps = 23/257 (8%)
Query: 1522 VKRTWHRHLKDKLT---HKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSL 1578
VK T + K+K KE S R R+ R S+ + H R S S +RSS
Sbjct: 1796 VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKR--SKSSEHKSRKRTSESRSRARKRSSK 1853
Query: 1579 ERRHHSPSQRSHCSPSRKNHSSPSE---RSWRSPSQRNHCSPPERSCHSLSERGLHSPSQ 1635
+ H S + RS R+ SS S R RS S+ P+ S ER S
Sbjct: 1854 SKSHRSQT-RSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKS-RERKRKRSSS 1911
Query: 1636 RSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRS----PSQRSHRGPSERSHCSPSE 1691
R +R + R +PS RS R RS S R RS PS+RS R PS RS +PS
Sbjct: 1912 RDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRS-RTPSRRSR-TPS- 1968
Query: 1692 RRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSE---RSHHSPSER 1748
RR R+PS+RS R PS RR +PS+RS RR RS R S S R +P R
Sbjct: 1969 RRSRTPSRRS-RTPS-RRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRR 2026
Query: 1749 R-HHSPSERSHCSPSER 1764
R SP R SER
Sbjct: 2027 RFSRSPIRRKRSRSSER 2043
Score = 82.0 bits (201), Expect = 5e-15
Identities = 100/289 (34%), Positives = 123/289 (42%), Gaps = 56/289 (19%)
Query: 1616 SPPERSCHSLSE-----------RGLHSPSQRSHRGPS----QRRHHSPSERSHRSPS-- 1658
S PER+ S SE + H S+++ ++R S RS RS S
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833
Query: 1659 ----ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPS 1714
+R+ S S R RS +SHR + RS RR S S+ RG RR S
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQT-RSRSRSRRRRRSSRSRSKSRG---RRSVSKE 1889
Query: 1715 KRSHRSPARRSHRSPS-ERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERR 1773
KR RSP HRS S ER S R + R +PS RS RSH RR
Sbjct: 1890 KRK-RSP---KHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS------RSHTPSRRRR 1939
Query: 1774 HRSPSERRHH--SPSEKSHHSPSERSHHSPS------ERRRHSPLERSRHSLLERSHRSP 1825
RS RR SPS +S +PS RS +PS RR +P RSR R R+P
Sbjct: 1940 SRSVGRRRSFSISPSRRS-RTPSRRS-RTPSRRSRTPSRRSRTPSRRSRTP--SRRSRTP 1995
Query: 1826 SERR------SHRSFERSHRRISERSHSP-SEKSHLSPLERSRCSPSER 1867
S RR RSF S R+ RS +P + SP+ R R SER
Sbjct: 1996 SRRRRSRSVVRRRSFSISPVRL-RRSRTPLRRRFSRSPIRRKRSRSSER 2043
Score = 76.3 bits (186), Expect = 3e-13
Identities = 85/299 (28%), Positives = 114/299 (38%), Gaps = 46/299 (15%)
Query: 1651 ERSHRSP-----SERSHRSSSERR------------HRSPSQRSHRGPSERSHCSPSERR 1693
+RS SP ER+ SSSE + H + +R E+ +
Sbjct: 1764 DRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKE-------K 1816
Query: 1694 HRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP 1753
R S RS S+ H KR+ S +R RS +SH S + S RR
Sbjct: 1817 KRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRR---- 1872
Query: 1754 SERSHCSPSERSHCSPSERR----HRSPS-ERRHHSPSEKSHHSPSERSHHSPSER-RRH 1807
S RS R S +R+ HRS S ER+ S + + +PS R R H
Sbjct: 1873 SSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSH 1932
Query: 1808 SPLERSRHSLLER--------SHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLER 1859
+P R R + R S RS + R R+ R R S RS +PS +S +P R
Sbjct: 1933 TPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR-TPSRR 1991
Query: 1860 SRCSPSERRGHSSSGKTCHSPSE---RSHRSPSGMRQGRTSERSHRSSCERTRHSPSEM 1915
SR RR S + S S R R+P R R+ R RS SP +
Sbjct: 1992 SRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRL 2050
Score = 68.6 bits (166), Expect = 6e-11
Identities = 78/250 (31%), Positives = 110/250 (44%), Gaps = 46/250 (18%)
Query: 1476 RTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLT 1535
R+ + SS+SK + + + S+ + + +R ++RGR R + +
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR------------RSVSKEKR 1891
Query: 1536 HKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSR 1595
+ H S RER + S R R+PS RS R H+PS+R R
Sbjct: 1892 KRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS-------RSHTPSRR------R 1938
Query: 1596 KNHSSPSERSWR-SPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSH 1654
++ S RS+ SPS+R+ +P RS +PS+RS R PS RR +PS RS
Sbjct: 1939 RSRSVGRRRSFSISPSRRSR-TPSRRS---------RTPSRRS-RTPS-RRSRTPSRRS- 1985
Query: 1655 RSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSE-RRHRSPSQRSHRGPSERRHHSP 1713
R+PS RS S RR RS +R SP RR R+P +R RR S
Sbjct: 1986 RTPSRRSRTPSRRRRSRSVVRR------RSFSISPVRLRRSRTPLRRRFSRSPIRRKRSR 2039
Query: 1714 SKRSHRSPAR 1723
S RSP R
Sbjct: 2040 SSERGRSPKR 2049
Score = 68.2 bits (165), Expect = 8e-11
Identities = 75/227 (33%), Positives = 97/227 (42%), Gaps = 36/227 (15%)
Query: 1710 HHSPSKRSHRSPARRSH-RSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCS 1768
H K +R + R S RS S+ S H +R S S S +SH
Sbjct: 1800 HEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH-- 1857
Query: 1769 PSERRHRSPSERRHHSPSEKSHHSPSERSHHSPS-ERRRHSPLERSRHSLLERSHRSPSE 1827
S+ R RS S RR S +S R S S E+R+ SP RS+ E
Sbjct: 1858 RSQTRSRSRSRRRRRSSRSRS----KSRGRRSVSKEKRKRSPKHRSKSR----------E 1903
Query: 1828 RRSHRSFERSHRR-ISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHR 1886
R+ RS R +R+ + RS +PS +S R R S S R S S SPS RS R
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS----ISPSRRS-R 1958
Query: 1887 SPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSR 1933
+PS R+ RT R R+ R+R PS R+ +PS RSR
Sbjct: 1959 TPS--RRSRTPSRRSRTPSRRSR---------TPSRRSR-TPSRRSR 1993
Score = 55.8 bits (133), Expect = 4e-07
Identities = 64/215 (29%), Positives = 83/215 (38%), Gaps = 29/215 (13%)
Query: 1727 RSPSERSHHSPSERSHHSPSERRHH-----SPSERSHCSPSERSHCSPSERRHRSPSERR 1781
RS + S ER+ S SE + + S ++ + + R S R
Sbjct: 1765 RSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRS 1824
Query: 1782 HHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRI 1841
S+ S H +R+ S S R+ S +S S RS RRS RS +S R
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR- 1883
Query: 1842 SERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSH 1901
RS S EK SP RS+ +R+ SS R +R R RT R
Sbjct: 1884 --RSVS-KEKRKRSPKHRSKSRERKRKRSSS----------RDNRKTVRARS-RTPSRRS 1929
Query: 1902 RSSCERTRHSPSEMRPGRPSGRNH---CSPSERSR 1933
RS H+PS R R GR SPS RSR
Sbjct: 1930 RS------HTPSRRRRSRSVGRRRSFSISPSRRSR 1958
Score = 47.8 bits (112), Expect = 1e-04
Identities = 53/192 (27%), Positives = 76/192 (39%), Gaps = 28/192 (14%)
Query: 1765 SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRS 1824
+H + ++R E+ S S S S+RS S + R+ + RSR +RS +S
Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDS--SLRSRSKRSKSSEHKSRKRTSESRSRAR--KRSSKS 1854
Query: 1825 PSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERS 1884
S R RS RS RR RS S S+ RG S K E+
Sbjct: 1855 KSHRSQTRSRSRSRRR-----------------RRSSRSRSKSRGRRSVSK------EKR 1891
Query: 1885 HRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS 1944
RSP + R +R SS + + + R R+H +PS R R + +S
Sbjct: 1892 KRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSH-TPSRRRRSRSVGRRRSFS 1950
Query: 1945 FPGERPSHSLSR 1956
R S + SR
Sbjct: 1951 ISPSRRSRTPSR 1962
Score = 47.0 bits (110), Expect = 2e-04
Identities = 63/210 (30%), Positives = 87/210 (41%), Gaps = 24/210 (11%)
Query: 1763 ERSHCSP-----SERRHRSPSERRHHSP---SEKSHHSPSERSHHSPSERRRHSPLERSR 1814
+RS SP ER S SE + K H S+++ + R E+ R
Sbjct: 1764 DRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKN-----KNRDKGEKEKKR 1818
Query: 1815 HSLLERSHRSPSERRSHRSFER-SHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSS 1873
S L RS S+ H+S +R S R R S KSH S RSR S S RR SS
Sbjct: 1819 DSSL-RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT-RSR-SRSRRRRRSSR 1875
Query: 1874 GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHC-SPSERS 1932
++ R RS S ++ R+ + HRS + S R R + R +PS RS
Sbjct: 1876 SRS----KSRGRRSVSKEKRKRSPK--HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS 1929
Query: 1933 RRSPLKEGLKYSFPGERPSHSLSRDFKNQT 1962
R + G R S S+S +++T
Sbjct: 1930 RSHTPSRRRRSRSVGRRRSFSISPSRRSRT 1959
Score = 42.4 bits (98), Expect = 0.005
Identities = 50/193 (25%), Positives = 86/193 (44%), Gaps = 16/193 (8%)
Query: 1157 EGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRKAKIYTQASKSPT-STI 1215
+G E + R R KRS+ S+++ R R RS K+K + ++S + S
Sbjct: 1811 KGEKEKKRDSSLRSR-SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869
Query: 1216 DLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKR 1275
+S S+S + RG+RS + ++ + R+P H ++ S S + R
Sbjct: 1870 RRRSSRSRSKS-------RGRRS---VSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVR 1919
Query: 1276 AKVRT-KKTSDSKYPMKRITKR-LRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQTS 1333
A+ RT + S S P +R R + + R F + +PSR RR R + ++
Sbjct: 1920 ARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSR 1979
Query: 1334 TASLKRQPKKPSQ 1346
T S R+ + PS+
Sbjct: 1980 TPS--RRSRTPSR 1990
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Query: 1730 SERSHHSPSERSHHSPSERRHHSP-SERSHCSPSERSHCSPSERRHRSP-SERRHHSPSE 1787
+ERS S ERS S ER SP +ERS S ERS S ER SP +ER S E
Sbjct: 1005 AERSMMSSYERSMMS-YERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYE 1063
Query: 1788 KSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERS 1837
+S S ERS SP R + R + S S S+ + +RS
Sbjct: 1064 RSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRS 1113
Score = 39.3 bits (90), Expect = 0.039
Identities = 45/128 (35%), Positives = 52/128 (40%), Gaps = 16/128 (12%)
Query: 1778 SERRHHSPSEKSHHSPSERSHHSP-SERRRHSPLERSRHSLLERSHRSPSERRSHRSFER 1836
+ER S E+S S ERS SP +ER S ERS S ERS SP RS S
Sbjct: 1005 AERSMMSSYERSMMS-YERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMS--- 1060
Query: 1837 SHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRT 1896
E+S +S ERS SP R S G S S S M
Sbjct: 1061 -----------AYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSA 1109
Query: 1897 SERSHRSS 1904
++RS SS
Sbjct: 1110 ADRSMMSS 1117
Score = 37.4 bits (85), Expect = 0.15
Identities = 40/110 (36%), Positives = 51/110 (46%), Gaps = 8/110 (7%)
Query: 1570 SERSQRSSLERRHHSPSQRSHCSP-SRKNHSSPSERSWRSPSQRNHCSP-PERSCHSLSE 1627
+ERS SS ER S +RS SP + ++ S ERS S +R+ SP ERS S E
Sbjct: 1005 AERSMMSSYERSMMS-YERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYE 1063
Query: 1628 RGLHSPSQRSHRGPSQRRH-----HSPSERSHRSPSERSHRSSSERRHRS 1672
R + S +RS P R S S S ++RS SS RS
Sbjct: 1064 RSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRS 1113
Score = 37.0 bits (84), Expect = 0.19
Identities = 43/119 (36%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 1698 SQRSHRGPSERRHHSPSKRSHRSP-ARRSHRSPSERSHHSPSERSHHSP-SERRHHSPSE 1755
++RS ER S +RS SP A RS S ERS S ERS SP +ER S E
Sbjct: 1005 AERSMMSSYERSMMS-YERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYE 1063
Query: 1756 RSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSR 1814
RS S ERS SP R S S S S +S ++R S R
Sbjct: 1064 RSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADR 1122
Score = 36.6 bits (83), Expect = 0.25
Identities = 39/112 (34%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 1706 SERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP-SERSHCSPSER 1764
+ER S +RS S R +ERS S ERS S ER SP +ERS S ER
Sbjct: 1005 AERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYER 1064
Query: 1765 SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHS 1816
S S ER SP R S S S +S +RS S
Sbjct: 1065 SMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMS 1116
Score = 35.8 bits (81), Expect = 0.43
Identities = 84/358 (23%), Positives = 129/358 (36%), Gaps = 85/358 (23%)
Query: 1259 VHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSREL 1318
V ++PE SES+ EK K D+ K+ R + ++ +S S +
Sbjct: 1772 VSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKS 1831
Query: 1319 AAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDG 1378
+ H RKR +++ + + KR K S + +S +R + R S GR+ V
Sbjct: 1832 SEHKSRKR--TSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSR-SKSRGRRSVSK 1888
Query: 1379 TRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSA 1438
+ ++ + +R+ S RD R TV+ RS
Sbjct: 1889 EK-----RKRSPKHRSKSRERKRKRSSSRDNRK--------------------TVRARSR 1923
Query: 1439 QQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQ 1498
RR+ S P R ++ SVG+ R+ S RS+ R+ T S+
Sbjct: 1924 TPSRRSRSHTPSRRR-------------RSRSVGR-RRSFSISPSRRSRTPSRRSRTPSR 1969
Query: 1499 ESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTR 1558
S+ TP R + R R RT PS R+R
Sbjct: 1970 RSR---TPSRRSRTPSR------------------------------RSRT---PSRRSR 1993
Query: 1559 HNPSWRNHRSPSERSQRSSLE----RRHHSPSQRSHC-SPSRKNHSSPSERSWRSPSQ 1611
PS R R + S+ RR +P +R SP R+ S SER RSP +
Sbjct: 1994 -TPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERG-RSPKR 2049
Score = 35.0 bits (79), Expect = 0.73
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSP-SERSHRSP 1657
S +ERS S +R+ S ++ER + S +RS +R SP +ERS S
Sbjct: 1002 SYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSA 1061
Query: 1658 SERSHRSSSERRHRSP 1673
ERS S+ ER SP
Sbjct: 1062 YERSMMSAYERSMMSP 1077
Score = 34.3 bits (77), Expect = 1.2
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 1626 SERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSP-SQRSHRGPSER 1684
+ER + S +RS + +ERS S ERS S+ ER SP ++RS ER
Sbjct: 1005 AERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYER 1064
Query: 1685 SHCSPSERRHRSP 1697
S S ER SP
Sbjct: 1065 SMMSAYERSMMSP 1077
Score = 33.9 bits (76), Expect = 1.6
Identities = 41/120 (34%), Positives = 51/120 (42%), Gaps = 12/120 (10%)
Query: 1658 SERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRS 1717
+ERS SS ER S + +ERS S ER S +RS P ++RS
Sbjct: 1005 AERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPM-------AERS 1057
Query: 1718 HRSPARRSHRSPSERSHHSP-SERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRS 1776
S RS S ERS SP ++RS S R S S S ++RS S RS
Sbjct: 1058 MMSAYERSMMSAYERSMMSPMADRSMMSMGADR----SMMSSYSAADRSMMSSYSAADRS 1113
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 100 bits (250), Expect = 1e-20
Identities = 93/244 (38%), Positives = 115/244 (47%), Gaps = 22/244 (9%)
Query: 1620 RSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHR 1679
RS S+ H +R+ S+ R S +SHRS + RS S RR RS RS
Sbjct: 1823 RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRS--RSRSRRRRRSSRSRSK- 1879
Query: 1680 GPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSH-HSPS 1738
S E+R RSP RS ER+ S R +R R R+PS RS H+PS
Sbjct: 1880 --SRGRRSVSKEKRKRSPKHRSKS--RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935
Query: 1739 ERSHHSPSERRHH---SPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSE 1795
R RR SPS RS +PS RS +PS RR R+PS RR +PS +S +PS
Sbjct: 1936 RRRRSRSVGRRRSFSISPSRRSR-TPSRRSR-TPS-RRSRTPS-RRSRTPSRRS-RTPSR 1990
Query: 1796 RSHHSPSERRRHSPLERSRHSLLE----RSHRSPSERRSHRS-FERSHRRISERSHSPSE 1850
RS +PS RRR + R R + R R+P RR RS R R SER SP
Sbjct: 1991 RS-RTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Query: 1851 KSHL 1854
+ L
Sbjct: 2050 LTDL 2053
Score = 93.2 bits (230), Expect = 2e-18
Identities = 106/307 (34%), Positives = 135/307 (43%), Gaps = 41/307 (13%)
Query: 1547 ERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSW 1606
ER SE + + E+S+++ + +R SR S SE
Sbjct: 1777 ERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKS 1836
Query: 1607 RSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS-S 1665
R + + +RS S S R SQ R S+RR S RS R RS S
Sbjct: 1837 RKRTSESRSRARKRSSKSKSHR-----SQTRSRSRSRRRRRSSRSRS----KSRGRRSVS 1887
Query: 1666 SERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSER-RHHSPSKRSHRSPARR 1724
E+R RSP RS ER S R +R + R PS R R H+PS+R RR
Sbjct: 1888 KEKRKRSPKHRSKS--RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRR------RR 1939
Query: 1725 SHRSPSERSHH-SPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHH 1783
S RS SPS RS +PS RR +PS RS +PS RR R+PS RR
Sbjct: 1940 SRSVGRRRSFSISPSRRSR-TPS-RRSRTPSRRSR-TPS---------RRSRTPS-RRSR 1986
Query: 1784 SPSEKSHHSPSERSHHSPSERRRH---SP--LERSRHSLLERSHRSPSERRSHRSFE--R 1836
+PS +S +PS R RRR SP L RSR L R RSP R+ RS E R
Sbjct: 1987 TPSRRS-RTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGR 2045
Query: 1837 SHRRISE 1843
S +R+++
Sbjct: 2046 SPKRLTD 2052
Score = 85.5 bits (210), Expect = 5e-16
Identities = 94/257 (36%), Positives = 115/257 (44%), Gaps = 23/257 (8%)
Query: 1522 VKRTWHRHLKDKLT---HKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSL 1578
VK T + K+K KE S R R+ R S+ + H R S S +RSS
Sbjct: 1796 VKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKR--SKSSEHKSRKRTSESRSRARKRSSK 1853
Query: 1579 ERRHHSPSQRSHCSPSRKNHSSPSE---RSWRSPSQRNHCSPPERSCHSLSERGLHSPSQ 1635
+ H S + RS R+ SS S R RS S+ P+ S ER S
Sbjct: 1854 SKSHRSQT-RSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKS-RERKRKRSSS 1911
Query: 1636 RSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRS----PSQRSHRGPSERSHCSPSE 1691
R +R + R +PS RS R RS S R RS PS+RS R PS RS +PS
Sbjct: 1912 RDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRS-RTPSRRSR-TPS- 1968
Query: 1692 RRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSE---RSHHSPSER 1748
RR R+PS+RS R PS RR +PS+RS RR RS R S S R +P R
Sbjct: 1969 RRSRTPSRRS-RTPS-RRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRR 2026
Query: 1749 R-HHSPSERSHCSPSER 1764
R SP R SER
Sbjct: 2027 RFSRSPIRRKRSRSSER 2043
Score = 82.0 bits (201), Expect = 5e-15
Identities = 100/289 (34%), Positives = 123/289 (42%), Gaps = 56/289 (19%)
Query: 1616 SPPERSCHSLSE-----------RGLHSPSQRSHRGPS----QRRHHSPSERSHRSPS-- 1658
S PER+ S SE + H S+++ ++R S RS RS S
Sbjct: 1774 SMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833
Query: 1659 ----ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPS 1714
+R+ S S R RS +SHR + RS RR S S+ RG RR S
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQT-RSRSRSRRRRRSSRSRSKSRG---RRSVSKE 1889
Query: 1715 KRSHRSPARRSHRSPS-ERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERR 1773
KR RSP HRS S ER S R + R +PS RS RSH RR
Sbjct: 1890 KRK-RSP---KHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS------RSHTPSRRRR 1939
Query: 1774 HRSPSERRHH--SPSEKSHHSPSERSHHSPS------ERRRHSPLERSRHSLLERSHRSP 1825
RS RR SPS +S +PS RS +PS RR +P RSR R R+P
Sbjct: 1940 SRSVGRRRSFSISPSRRS-RTPSRRS-RTPSRRSRTPSRRSRTPSRRSRTP--SRRSRTP 1995
Query: 1826 SERR------SHRSFERSHRRISERSHSP-SEKSHLSPLERSRCSPSER 1867
S RR RSF S R+ RS +P + SP+ R R SER
Sbjct: 1996 SRRRRSRSVVRRRSFSISPVRL-RRSRTPLRRRFSRSPIRRKRSRSSER 2043
Score = 76.3 bits (186), Expect = 3e-13
Identities = 85/299 (28%), Positives = 114/299 (38%), Gaps = 46/299 (15%)
Query: 1651 ERSHRSP-----SERSHRSSSERR------------HRSPSQRSHRGPSERSHCSPSERR 1693
+RS SP ER+ SSSE + H + +R E+ +
Sbjct: 1764 DRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKE-------K 1816
Query: 1694 HRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP 1753
R S RS S+ H KR+ S +R RS +SH S + S RR
Sbjct: 1817 KRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRR---- 1872
Query: 1754 SERSHCSPSERSHCSPSERR----HRSPS-ERRHHSPSEKSHHSPSERSHHSPSER-RRH 1807
S RS R S +R+ HRS S ER+ S + + +PS R R H
Sbjct: 1873 SSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSH 1932
Query: 1808 SPLERSRHSLLER--------SHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLER 1859
+P R R + R S RS + R R+ R R S RS +PS +S +P R
Sbjct: 1933 TPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSR-TPSRR 1991
Query: 1860 SRCSPSERRGHSSSGKTCHSPSE---RSHRSPSGMRQGRTSERSHRSSCERTRHSPSEM 1915
SR RR S + S S R R+P R R+ R RS SP +
Sbjct: 1992 SRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKRL 2050
Score = 68.6 bits (166), Expect = 6e-11
Identities = 78/250 (31%), Positives = 110/250 (44%), Gaps = 46/250 (18%)
Query: 1476 RTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLT 1535
R+ + SS+SK + + + S+ + + +R ++RGR R + +
Sbjct: 1844 RSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR------------RSVSKEKR 1891
Query: 1536 HKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSR 1595
+ H S RER + S R R+PS RS R H+PS+R R
Sbjct: 1892 KRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS-------RSHTPSRR------R 1938
Query: 1596 KNHSSPSERSWR-SPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSH 1654
++ S RS+ SPS+R+ +P RS +PS+RS R PS RR +PS RS
Sbjct: 1939 RSRSVGRRRSFSISPSRRSR-TPSRRS---------RTPSRRS-RTPS-RRSRTPSRRS- 1985
Query: 1655 RSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSE-RRHRSPSQRSHRGPSERRHHSP 1713
R+PS RS S RR RS +R SP RR R+P +R RR S
Sbjct: 1986 RTPSRRSRTPSRRRRSRSVVRR------RSFSISPVRLRRSRTPLRRRFSRSPIRRKRSR 2039
Query: 1714 SKRSHRSPAR 1723
S RSP R
Sbjct: 2040 SSERGRSPKR 2049
Score = 68.2 bits (165), Expect = 8e-11
Identities = 75/227 (33%), Positives = 97/227 (42%), Gaps = 36/227 (15%)
Query: 1710 HHSPSKRSHRSPARRSH-RSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCS 1768
H K +R + R S RS S+ S H +R S S S +SH
Sbjct: 1800 HEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSH-- 1857
Query: 1769 PSERRHRSPSERRHHSPSEKSHHSPSERSHHSPS-ERRRHSPLERSRHSLLERSHRSPSE 1827
S+ R RS S RR S +S R S S E+R+ SP RS+ E
Sbjct: 1858 RSQTRSRSRSRRRRRSSRSRS----KSRGRRSVSKEKRKRSPKHRSKSR----------E 1903
Query: 1828 RRSHRSFERSHRR-ISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHR 1886
R+ RS R +R+ + RS +PS +S R R S S R S S SPS RS R
Sbjct: 1904 RKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS----ISPSRRS-R 1958
Query: 1887 SPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSR 1933
+PS R+ RT R R+ R+R PS R+ +PS RSR
Sbjct: 1959 TPS--RRSRTPSRRSRTPSRRSR---------TPSRRSR-TPSRRSR 1993
Score = 55.8 bits (133), Expect = 4e-07
Identities = 64/215 (29%), Positives = 83/215 (38%), Gaps = 29/215 (13%)
Query: 1727 RSPSERSHHSPSERSHHSPSERRHH-----SPSERSHCSPSERSHCSPSERRHRSPSERR 1781
RS + S ER+ S SE + + S ++ + + R S R
Sbjct: 1765 RSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRS 1824
Query: 1782 HHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRI 1841
S+ S H +R+ S S R+ S +S S RS RRS RS +S R
Sbjct: 1825 RSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGR- 1883
Query: 1842 SERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSH 1901
RS S EK SP RS+ +R+ SS R +R R RT R
Sbjct: 1884 --RSVS-KEKRKRSPKHRSKSRERKRKRSSS----------RDNRKTVRARS-RTPSRRS 1929
Query: 1902 RSSCERTRHSPSEMRPGRPSGRNH---CSPSERSR 1933
RS H+PS R R GR SPS RSR
Sbjct: 1930 RS------HTPSRRRRSRSVGRRRSFSISPSRRSR 1958
Score = 47.8 bits (112), Expect = 1e-04
Identities = 53/192 (27%), Positives = 76/192 (39%), Gaps = 28/192 (14%)
Query: 1765 SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRS 1824
+H + ++R E+ S S S S+RS S + R+ + RSR +RS +S
Sbjct: 1799 THEKSKKNKNRDKGEKEKKRDS--SLRSRSKRSKSSEHKSRKRTSESRSRAR--KRSSKS 1854
Query: 1825 PSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERS 1884
S R RS RS RR RS S S+ RG S K E+
Sbjct: 1855 KSHRSQTRSRSRSRRR-----------------RRSSRSRSKSRGRRSVSK------EKR 1891
Query: 1885 HRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS 1944
RSP + R +R SS + + + R R+H +PS R R + +S
Sbjct: 1892 KRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSH-TPSRRRRSRSVGRRRSFS 1950
Query: 1945 FPGERPSHSLSR 1956
R S + SR
Sbjct: 1951 ISPSRRSRTPSR 1962
Score = 47.0 bits (110), Expect = 2e-04
Identities = 63/210 (30%), Positives = 87/210 (41%), Gaps = 24/210 (11%)
Query: 1763 ERSHCSP-----SERRHRSPSERRHHSP---SEKSHHSPSERSHHSPSERRRHSPLERSR 1814
+RS SP ER S SE + K H S+++ + R E+ R
Sbjct: 1764 DRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKN-----KNRDKGEKEKKR 1818
Query: 1815 HSLLERSHRSPSERRSHRSFER-SHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSS 1873
S L RS S+ H+S +R S R R S KSH S RSR S S RR SS
Sbjct: 1819 DSSL-RSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQT-RSR-SRSRRRRRSSR 1875
Query: 1874 GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHC-SPSERS 1932
++ R RS S ++ R+ + HRS + S R R + R +PS RS
Sbjct: 1876 SRS----KSRGRRSVSKEKRKRSPK--HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRS 1929
Query: 1933 RRSPLKEGLKYSFPGERPSHSLSRDFKNQT 1962
R + G R S S+S +++T
Sbjct: 1930 RSHTPSRRRRSRSVGRRRSFSISPSRRSRT 1959
Score = 42.4 bits (98), Expect = 0.005
Identities = 50/193 (25%), Positives = 86/193 (44%), Gaps = 16/193 (8%)
Query: 1157 EGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRKAKIYTQASKSPT-STI 1215
+G E + R R KRS+ S+++ R R RS K+K + ++S + S
Sbjct: 1811 KGEKEKKRDSSLRSR-SKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869
Query: 1216 DLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKR 1275
+S S+S + RG+RS + ++ + R+P H ++ S S + R
Sbjct: 1870 RRRSSRSRSKS-------RGRRS---VSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVR 1919
Query: 1276 AKVRT-KKTSDSKYPMKRITKR-LRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQTS 1333
A+ RT + S S P +R R + + R F + +PSR RR R + ++
Sbjct: 1920 ARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSR 1979
Query: 1334 TASLKRQPKKPSQ 1346
T S R+ + PS+
Sbjct: 1980 TPS--RRSRTPSR 1990
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/110 (38%), Positives = 51/110 (46%), Gaps = 3/110 (2%)
Query: 1730 SERSHHSPSERSHHSPSERRHHSP-SERSHCSPSERSHCSPSERRHRSP-SERRHHSPSE 1787
+ERS S ERS S ER SP +ERS S ERS S ER SP +ER S E
Sbjct: 1005 AERSMMSSYERSMMS-YERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYE 1063
Query: 1788 KSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERS 1837
+S S ERS SP R + R + S S S+ + +RS
Sbjct: 1064 RSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRS 1113
Score = 39.3 bits (90), Expect = 0.039
Identities = 45/128 (35%), Positives = 52/128 (40%), Gaps = 16/128 (12%)
Query: 1778 SERRHHSPSEKSHHSPSERSHHSP-SERRRHSPLERSRHSLLERSHRSPSERRSHRSFER 1836
+ER S E+S S ERS SP +ER S ERS S ERS SP RS S
Sbjct: 1005 AERSMMSSYERSMMS-YERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMS--- 1060
Query: 1837 SHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRT 1896
E+S +S ERS SP R S G S S S M
Sbjct: 1061 -----------AYERSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSA 1109
Query: 1897 SERSHRSS 1904
++RS SS
Sbjct: 1110 ADRSMMSS 1117
Score = 37.4 bits (85), Expect = 0.15
Identities = 40/110 (36%), Positives = 51/110 (46%), Gaps = 8/110 (7%)
Query: 1570 SERSQRSSLERRHHSPSQRSHCSP-SRKNHSSPSERSWRSPSQRNHCSP-PERSCHSLSE 1627
+ERS SS ER S +RS SP + ++ S ERS S +R+ SP ERS S E
Sbjct: 1005 AERSMMSSYERSMMS-YERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYE 1063
Query: 1628 RGLHSPSQRSHRGPSQRRH-----HSPSERSHRSPSERSHRSSSERRHRS 1672
R + S +RS P R S S S ++RS SS RS
Sbjct: 1064 RSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRS 1113
Score = 37.0 bits (84), Expect = 0.19
Identities = 43/119 (36%), Positives = 50/119 (42%), Gaps = 3/119 (2%)
Query: 1698 SQRSHRGPSERRHHSPSKRSHRSP-ARRSHRSPSERSHHSPSERSHHSP-SERRHHSPSE 1755
++RS ER S +RS SP A RS S ERS S ERS SP +ER S E
Sbjct: 1005 AERSMMSSYERSMMS-YERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYE 1063
Query: 1756 RSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSR 1814
RS S ERS SP R S S S S +S ++R S R
Sbjct: 1064 RSMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMSSYTADR 1122
Score = 36.6 bits (83), Expect = 0.25
Identities = 39/112 (34%), Positives = 45/112 (40%), Gaps = 1/112 (0%)
Query: 1706 SERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP-SERSHCSPSER 1764
+ER S +RS S R +ERS S ERS S ER SP +ERS S ER
Sbjct: 1005 AERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYER 1064
Query: 1765 SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHS 1816
S S ER SP R S S S +S +RS S
Sbjct: 1065 SMMSAYERSMMSPMADRSMMSMGADRSMMSSYSAADRSMMSSYSAADRSMMS 1116
Score = 35.8 bits (81), Expect = 0.43
Identities = 84/358 (23%), Positives = 129/358 (36%), Gaps = 85/358 (23%)
Query: 1259 VHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSREL 1318
V ++PE SES+ EK K D+ K+ R + ++ +S S +
Sbjct: 1772 VSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKS 1831
Query: 1319 AAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDG 1378
+ H RKR +++ + + KR K S + +S +R + R S GR+ V
Sbjct: 1832 SEHKSRKR--TSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSR-SKSRGRRSVSK 1888
Query: 1379 TRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSA 1438
+ ++ + +R+ S RD R TV+ RS
Sbjct: 1889 EK-----RKRSPKHRSKSRERKRKRSSSRDNRK--------------------TVRARSR 1923
Query: 1439 QQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQ 1498
RR+ S P R ++ SVG+ R+ S RS+ R+ T S+
Sbjct: 1924 TPSRRSRSHTPSRRR-------------RSRSVGR-RRSFSISPSRRSRTPSRRSRTPSR 1969
Query: 1499 ESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTR 1558
S+ TP R + R R RT PS R+R
Sbjct: 1970 RSR---TPSRRSRTPSR------------------------------RSRT---PSRRSR 1993
Query: 1559 HNPSWRNHRSPSERSQRSSLE----RRHHSPSQRSHC-SPSRKNHSSPSERSWRSPSQ 1611
PS R R + S+ RR +P +R SP R+ S SER RSP +
Sbjct: 1994 -TPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERG-RSPKR 2049
Score = 35.0 bits (79), Expect = 0.73
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Query: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSP-SERSHRSP 1657
S +ERS S +R+ S ++ER + S +RS +R SP +ERS S
Sbjct: 1002 SYAAERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSA 1061
Query: 1658 SERSHRSSSERRHRSP 1673
ERS S+ ER SP
Sbjct: 1062 YERSMMSAYERSMMSP 1077
Score = 34.3 bits (77), Expect = 1.2
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 1626 SERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSP-SQRSHRGPSER 1684
+ER + S +RS + +ERS S ERS S+ ER SP ++RS ER
Sbjct: 1005 AERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPMAERSMMSAYER 1064
Query: 1685 SHCSPSERRHRSP 1697
S S ER SP
Sbjct: 1065 SMMSAYERSMMSP 1077
Score = 33.9 bits (76), Expect = 1.6
Identities = 41/120 (34%), Positives = 51/120 (42%), Gaps = 12/120 (10%)
Query: 1658 SERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRS 1717
+ERS SS ER S + +ERS S ER S +RS P ++RS
Sbjct: 1005 AERSMMSSYERSMMSYERSMMSPMAERSMMSAYERSMMSAYERSMMSPM-------AERS 1057
Query: 1718 HRSPARRSHRSPSERSHHSP-SERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRS 1776
S RS S ERS SP ++RS S R S S S ++RS S RS
Sbjct: 1058 MMSAYERSMMSAYERSMMSPMADRSMMSMGADR----SMMSSYSAADRSMMSSYSAADRS 1113
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 96.3 bits (238), Expect = 3e-19
Identities = 128/505 (25%), Positives = 184/505 (36%), Gaps = 60/505 (11%)
Query: 1467 QTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTW 1526
Q +S GQ + ++ SS +++ R++ S +S +R G S V+ +
Sbjct: 686 QNSSSGQAASSHEQARSSAGERHGSRHQLQSADS-------SRHSGTGHGQASSAVRDSG 738
Query: 1527 HRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPS 1586
HR H ++ G H + + +S E ++ S ER S S
Sbjct: 739 HRGSSGSQATDSEGHSEDSDTQSVSG------HGQAGHHQQSHQESARDRSGERSRRSGS 792
Query: 1587 QRSHCSPSRKNHSSPSERSWRSPSQ-----RNHCSPPERSCHSLSERGLHSPSQRSHRGP 1641
S +++ SS W PS +H + S HS S+ G + R H G
Sbjct: 793 FLYQVSTHKQSESS---HGWTGPSTGVRQGSHHEQARDNSRHSASQDG--QDTIRGHPGS 847
Query: 1642 SQR----RHHSPS-ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSER---R 1693
S+R HH S +RS S S SH +S R S Q R S + R R
Sbjct: 848 SRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSR 907
Query: 1694 HRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP 1753
H ++ HS + + +R S R S S S SE H SER S
Sbjct: 908 HSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE-GHSEDSERWSGSA 966
Query: 1754 SERSHCSPSERSHCSPSERRHRSPSERRHHSP-SEKSHHSPSERSHHSPSERRRHSPLER 1812
S S E+S RH S R HH + H + S R +P
Sbjct: 967 SRNHRGSAQEQS-------RHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAA 1019
Query: 1813 SRHSLLERSHRSPSER---RSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRG 1869
S H E++ SP ER R +S + S R + S S S+ G
Sbjct: 1020 SSH---EQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEG 1076
Query: 1870 HSS-------SGKTCHSPSERSH----RSPSGMRQGRTSERSHRSSC---ERTRHSPSEM 1915
HS SG P ++SH R SG R GR+ ++ S + H +
Sbjct: 1077 HSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRT 1136
Query: 1916 RPGRPSGRNHCSPSERSRRSPLKEG 1940
GR G +H + SR S +EG
Sbjct: 1137 STGRRQGSHHEQARDSSRHSASQEG 1161
Score = 90.9 bits (224), Expect = 1e-17
Identities = 152/648 (23%), Positives = 218/648 (33%), Gaps = 113/648 (17%)
Query: 1429 WGGTVQCR---SAQQPRRAYSFQPRPLRLPKP-------TDSQSGIAF-QTASVGQPLRT 1477
W G+ SAQ+ R S PR + + + QSG QT+S GQ +
Sbjct: 2907 WSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASS 2966
Query: 1478 VQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHK 1537
++ SS +++ ++ S+ S++ G S V+ + HR
Sbjct: 2967 HEQARSSAGERHGSHHQQSADSSRHSGI--------GHGQASSAVRDSGHRGYSGSQASD 3018
Query: 1538 EHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKN 1597
H + H + + +S E ++ S E HS S S ++
Sbjct: 3019 NEGHSE------DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQS 3072
Query: 1598 HSSPSERSWRSPSQRN-----HCSPPERSCHSLSERGLHSPSQR--SHRGPSQRRHHSPS 1650
SS W PS R H + S HS S+ G + S RG Q HH S
Sbjct: 3073 ESS---HGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHS 3129
Query: 1651 -ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHC---SPSERRHRSPSQRSHRGPS 1706
+ S S S SH +S R S Q R S + S RH +
Sbjct: 3130 VDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHA 3189
Query: 1707 ERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERS- 1765
+ HS + + +RRS R S S S SE H SER S S S E+S
Sbjct: 3190 DISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE-GHSEDSERWSGSASRNHRGSVQEQSR 3248
Query: 1766 HCSPSERRHRSPSERRHHSPS----------------------EKSHHSPSERS---HHS 1800
H S R H HS E++ SP ER H
Sbjct: 3249 HGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQ 3308
Query: 1801 PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSH--LSPLE 1858
++ RHS + R + S R R S S H SE S + S H P +
Sbjct: 3309 SADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH---SEESDTQSVSGHGQAGPHQ 3365
Query: 1859 RSRCSPSERRGHSSSGKT--------CHSPSERSH---RSPSGMRQGRTSERSHRSS--- 1904
+S + R SG++ H SE +H R+ +G RQG E++ SS
Sbjct: 3366 QSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHS 3425
Query: 1905 ----------------------------CERTRHSPSEMRPGRPSGRNHCSPSERSRRSP 1936
+R+ HS S GR+ S + RS
Sbjct: 3426 ASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSA 3485
Query: 1937 LKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPEATR 1984
++ G+ HS S + T + H GQ P +R
Sbjct: 3486 SRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSR 3533
Score = 87.0 bits (214), Expect = 2e-16
Identities = 107/454 (23%), Positives = 153/454 (33%), Gaps = 29/454 (6%)
Query: 1535 THKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPS 1594
+H E S + G H S R R S Q S++R HS S SH +
Sbjct: 3413 SHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQ--SVDRSGHSGSHHSHTTSQ 3470
Query: 1595 RKNHSSPSERSWRSPSQ--RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSER 1652
++ +S + RS S+ RN + S HS S S S R + S R
Sbjct: 3471 GRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPR 3530
Query: 1653 SHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHS 1712
+ R+ + S + H S+R G + R+H ++ + R S+ +R H
Sbjct: 3531 TSRNQGSSVSQDSDSQGHSEDSER-WSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHG 3589
Query: 1713 PSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR--HHSPSERSHCSPSERSHCSPS 1770
S S R + S S E++ S ER HH S S
Sbjct: 3590 HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSS------------ 3637
Query: 1771 ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERS--RHSLLERSHRSPSER 1828
RH + S S H S S S SE +S H +S E
Sbjct: 3638 --RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 3695
Query: 1829 RSHRSFERSHR------RISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSE 1882
RS RS R ++S S S P R + SS + +
Sbjct: 3696 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQ 3755
Query: 1883 RSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLK 1942
+ R G R+G H S +R+ HS S GR+ S + RS +E
Sbjct: 3756 DTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRN 3815
Query: 1943 YSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
G+ HS SR + T + H G+
Sbjct: 3816 EEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGE 3849
Score = 84.7 bits (208), Expect = 8e-16
Identities = 166/702 (23%), Positives = 237/702 (33%), Gaps = 116/702 (16%)
Query: 1355 QSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADK 1414
++ RA + H + VG+ +G R W S Q++ +R SA +
Sbjct: 2536 EASSRADSSGH---SQVGQGQSEGPRTSRNWGSSF---SQDSDSQGHSEDSERWSGSASR 2589
Query: 1415 LTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAF-QTASVGQ 1473
GS +Q L G+ RS Q+ R + R QSG QT+S GQ
Sbjct: 2590 -NHHGSAQEQ---LRDGSRHPRSHQEDRAGHGHSADSSR-------QSGTRHTQTSSGGQ 2638
Query: 1474 PLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDK 1533
+ ++ SS +++ ++ S+ S++ G S V+ + HR
Sbjct: 2639 AASSHEQARSSAGERHGSHHQQSADSSRHSGI--------GHGQASSAVRDSGHRGYSGS 2690
Query: 1534 LTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSP 1593
H + H + + +S E ++ S E HS S S
Sbjct: 2691 QASDNEGHSE------DSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVST 2744
Query: 1594 SRKNHSSPSERSWRSPSQRN-----HCSPPERSCHSLSERGLHSPSQR--SHRGPSQRRH 1646
++ SS W PS R H + S HS S+ G + S RG Q H
Sbjct: 2745 HEQSESS---HGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYH 2801
Query: 1647 HSPS-ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHC---SPSERRHRSPSQRSH 1702
H S + S S S SH +S R S Q R S + S RH
Sbjct: 2802 HEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEA 2861
Query: 1703 RGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPS 1762
++ HS + + +RRS R S S S SE H SER S S H S
Sbjct: 2862 STHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE-GHSEDSERWSGSASRNHHGSAQ 2920
Query: 1763 ER------------------SHCSPSER----RHRSPSERRHHSPS-EKSHHSPSER--S 1797
E+ H + S R RH S + S E++ S ER S
Sbjct: 2921 EQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGS 2980
Query: 1798 HHSPS-ERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISER----SHSPSEKS 1852
HH S + RHS + + S R S S H S+ +H +
Sbjct: 2981 HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSH 3040
Query: 1853 HLSPLERSRCSPSERRGHSSS---GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTR 1909
S E +R E GHS S + H SE SH +GR R H + + +R
Sbjct: 3041 QQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSR-HEQAQDSSR 3099
Query: 1910 HS------------PSEMRPGRPS-----------------------GRNHCSPSERSRR 1934
HS P R GR GR+ S + R
Sbjct: 3100 HSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR 3159
Query: 1935 SPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
S + G+ HS+SR + T + H GQ
Sbjct: 3160 SASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQ 3201
Score = 84.3 bits (207), Expect = 1e-15
Identities = 116/469 (24%), Positives = 165/469 (35%), Gaps = 61/469 (13%)
Query: 1535 THKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPS 1594
+H E S + G H S R R S Q S++R HS S SH +
Sbjct: 1144 SHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQ--SVDRSGHSGSHHSHTTSQ 1201
Query: 1595 RKNHSSPSERSWRSPSQ-----------------RNH--CSPPERSCHSLSERGLHSPSQ 1635
++ +S + RS S+ R+H S + S HS + S S+
Sbjct: 1202 GRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSR 1261
Query: 1636 RS-HRGPS------QRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS 1688
S H+G S RH SER S S H SS E+ S+ R P
Sbjct: 1262 TSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQ-----SRDGSRHPGFHQEDR 1316
Query: 1689 PSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER---SHHSPSERSHHSP 1745
S S++S +E H + SH ++ SP ER H ++ S HS
Sbjct: 1317 ASHGHSADSSRQSGTHHTESSSHGQAVSSH----EQARSSPGERHGSRHQQSADSSRHSG 1372
Query: 1746 SERRHHSPSER------SHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHH 1799
R S + R S S S + +S S P ++SH +
Sbjct: 1373 IGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSG 1432
Query: 1800 SPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLER 1859
S R R + S H E +H + R R + + HS S+ +
Sbjct: 1433 ESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQ----DT 1488
Query: 1860 SRCSPSERRG-------HSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSP 1912
R P RG S ++ HS SH +P G + RS+ +TR+
Sbjct: 1489 IRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEE 1548
Query: 1913 SEMRPGRPSGRNHCSPSER---SRRSPLKEGLKY-SFPGERPSHSLSRD 1957
R SG H PS R SR S + +G S R S+S+D
Sbjct: 1549 QSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQD 1597
Score = 83.2 bits (204), Expect = 2e-15
Identities = 140/570 (24%), Positives = 206/570 (36%), Gaps = 104/570 (18%)
Query: 1429 WGGTVQCR---SAQQPRRAYSFQPRPLRLPKP-------TDSQSGIAF-QTASVGQPLRT 1477
W G+ SAQ+ R S PR + + QSG +T+S GQ +
Sbjct: 962 WSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASS 1021
Query: 1478 VQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWH-----RHLKD 1532
++ SS +++ R++ S+ S++ P R QA S V+ + H D
Sbjct: 1022 HEQARSSPGERHGSRHQQSADSSRHSGIP--RRQA------SSAVRDSGHWGSSGSQASD 1073
Query: 1533 KLTHKEHNHPSFYRERTPRGPSERTRHNPS--WRNHRSPSERS--QRSSLERRHHSPSQR 1588
H E + GP +++ + W RS S + S + S R
Sbjct: 1074 SEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGR 1133
Query: 1589 SHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQR--SHRGPSQRRH 1646
+ S R+ S +H + S HS S+ G + S RG Q H
Sbjct: 1134 TRTSTGRRQGS-------------HHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSH 1180
Query: 1647 HSPS-ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGP 1705
H S +RS S S SH +S R S SH RS + + +S H G
Sbjct: 1181 HEQSVDRSGHSGSHHSHTTSQGR-----SDASHGQSGSRSASRQTRKDKQSGDGSRHSGS 1235
Query: 1706 SERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERS 1765
RHH + S ++ S HS + S S H S S S SER
Sbjct: 1236 ---RHHEAA-------------SWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSER- 1278
Query: 1766 HCSPSERRHRSPSERRHHSPSEKSH--------HSPSERSHHSPSERRRHS---PLERSR 1814
H SER S S H S E+S H SH ++ R S E S
Sbjct: 1279 HSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSS 1338
Query: 1815 HSLLERSHR----SPSERRSHRSFERS---------HRRIS----ERSHSPSEKSHLSPL 1857
H SH SP ER R + + HR+ S + H S S ++
Sbjct: 1339 HGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNS 1398
Query: 1858 ERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRP 1917
E S+ + S+ G+ P ++SH+ + + G +S RS + + H SE
Sbjct: 1399 E-GHSEDSDTQSVSAHGQA--GPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTH 1455
Query: 1918 GRPS-------GRNHCSPSERSRRSPLKEG 1940
G+ + G H SR S ++G
Sbjct: 1456 GQTAPSTGGRQGSRHEQARNSSRHSASQDG 1485
Score = 82.8 bits (203), Expect = 3e-15
Identities = 138/582 (23%), Positives = 208/582 (35%), Gaps = 69/582 (11%)
Query: 1434 QCRSAQQPRRAYSFQPRPLRLPKPTDSQ--SGIAFQTASVGQPLRTVQKDSSSRSKKNFY 1491
Q S+ + R+ + R + DS SGI + AS + +DS R
Sbjct: 1341 QAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQAS------SAVRDSGHRGSSG-- 1392
Query: 1492 RNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPR 1551
++ ++ E + + V A G+ P +++ + + SF + +
Sbjct: 1393 -SQVTNSEGHSEDSDTQSVSAHGQ---AGPHQQSHKESARGQSGESSGRSRSFLYQVSSH 1448
Query: 1552 GPSERTRHN--PSWRNHRSPSERSQRSSLERRHHSPSQ------RSHCSPSRKN-----H 1598
SE T PS + R+S HS SQ R H SR H
Sbjct: 1449 EQSESTHGQTAPSTGGRQGSRHEQARNS---SRHSASQDGQDTIRGHPGSSRGGRQGSYH 1505
Query: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPS 1658
+RS S +H +P RS S + G S S+++ S H PS
Sbjct: 1506 EQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPS 1565
Query: 1659 ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQ----RSHRGPSERRHHSPS 1714
R+ S+ S G E + S R+ S SQ H SERR S S
Sbjct: 1566 TRA----------GSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESAS 1615
Query: 1715 KRSHRSPARRS-HRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERR 1773
+ + S +S H S + RSH HS R S H S + S+ +
Sbjct: 1616 RNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQ---SGTRHAETSSGGQAASSQEQ 1672
Query: 1774 HRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRS 1833
RS RH S ++S S ++ R+ S + S + S S SE S S
Sbjct: 1673 ARSSPGERHGSRHQQSADSSTD---SGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEES 1729
Query: 1834 FERSHRRISERSHS-PSEKSHLSPLERSRCSPSERRGHSSS---GKTCHSPSERSHRSPS 1889
+S +S + P ++SH E +R ER G S S + H SE +H
Sbjct: 1730 DTQS---VSAHGQAGPHQQSH---QESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTG 1783
Query: 1890 GMRQGRTSERSHRSSCERTRHSPSEM-------RPGRPSGRNHCSPSERSRRSPLKEGLK 1942
GR R H + + +RHS S+ PG G S E+S S G
Sbjct: 1784 PSTGGRQRSR-HEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSH 1842
Query: 1943 YSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPEATR 1984
+S + +SR ++ T ++G R +R
Sbjct: 1843 HSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSR 1884
Score = 82.8 bits (203), Expect = 3e-15
Identities = 143/577 (24%), Positives = 218/577 (37%), Gaps = 82/577 (14%)
Query: 1431 GTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAF-QTASVGQPLRTVQKDSSSRSKKN 1489
G+ RS Q+ R ++ R QSG +T+S GQ + ++ SS +++
Sbjct: 1629 GSRNPRSHQEDRASHGHSAESSR-------QSGTRHAETSSGGQAASSQEQARSSPGERH 1681
Query: 1490 FYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERT 1549
R++ S+ S + GT + ++ S + + D H E +
Sbjct: 1682 GSRHQQSADSSTD---SGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHG 1738
Query: 1550 PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSP 1609
GP +++ H S R ERS RS S ++S + R S+ + R
Sbjct: 1739 QAGPHQQS-HQESTRGQSG--ERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHE 1795
Query: 1610 SQRNHCSPPERSCHSLSERGLHSPSQR--SHRGPSQRRH---------HSPSERSHRSPS 1658
R + S HS S+ G + S RG Q H HS S SH +
Sbjct: 1796 QAR------DSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQ 1849
Query: 1659 ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQR--SHRGPSERRHHSPSKR 1716
ERS S + RS S+++ S RH S R S R + S R
Sbjct: 1850 ERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPR 1909
Query: 1717 SHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERS----------HCSPSERSH 1766
+ R+ + + H SER S S S E+S H + H
Sbjct: 1910 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGH 1969
Query: 1767 CSPSER----RHRSPSERRHHSPS-EKSHHSPSER--SHHSPSERRRHSPLERSRHSLLE 1819
+ S R RH S R + S E++ S ER SHH + + SRHS +
Sbjct: 1970 SADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHH------QLQSADSSRHSGIG 2023
Query: 1820 RSHRSPSERRS-HRSFERSHRRISERSHSPSEKSHLS------PLERSRCSPSERRGHSS 1872
S + R S HR + S SE S+ +S P ++S + + S
Sbjct: 2024 HGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGES 2083
Query: 1873 SGK--------TCHSPSERSH--RSPS-GMRQGRTSERSHRSSCERTRHSPSEMRPGRPS 1921
SG+ + H SE +H +PS G RQG +++ SS RHS S+ G+ +
Sbjct: 2084 SGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSS----RHSASQ--EGQDT 2137
Query: 1922 GRNHCSPSERSRRSPLKEGL--KYSFPGERPSHSLSR 1956
R H PS R+ +E + G SH+ S+
Sbjct: 2138 IRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQ 2174
Score = 82.0 bits (201), Expect = 5e-15
Identities = 135/531 (25%), Positives = 201/531 (37%), Gaps = 71/531 (13%)
Query: 1466 FQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPV--- 1522
+Q +S Q T + + S + R+E + S++ ++ + RG PGS
Sbjct: 1443 YQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGH--PGSSRGGR 1500
Query: 1523 KRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRH 1582
+ ++H D+ H ++H TP+G S+ + H S S R++ S +
Sbjct: 1501 QGSYHEQSVDRSGHSGYHHS----HTTPQGRSDAS-HGQSGPRSASRQTRNEEQSGDGSR 1555
Query: 1583 HSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQ-RSHRGP 1641
HS S+ H PS R+ S+ + E + S R S SQ R G
Sbjct: 1556 HSGSR----------HHEPSTRA--GSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEG- 1602
Query: 1642 SQRRHHSPSERSHRSPSERSHRSSSER-RHRSPSQRSHR------GPSERS-------HC 1687
H SER S S + S+ E+ RH S + RSH+ G S S H
Sbjct: 1603 ----HSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHA 1658
Query: 1688 SPSERRHRSPSQRSHRGPSERRHHSPSKRSHRS-----PARRSHRSPSERSHHSPSERSH 1742
S + SQ R RH S ++S S RR S S + S S
Sbjct: 1659 ETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQ 1718
Query: 1743 HSPSERRH-----HSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERS 1797
S SE S S P ++SH + + S R + S H SE +
Sbjct: 1719 ASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESA 1778
Query: 1798 H--HSPS----ERRRHSPL-ERSRHSLLERSHRS----PSERRSHRSFERSHRRISERSH 1846
H PS +R RH + SRHS + + P R R + + H
Sbjct: 1779 HGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGH 1838
Query: 1847 SPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCE 1906
S S SH + ERS S RG S S ++ + +S G R + S +
Sbjct: 1839 SGSHHSHTTSQERSDVS----RGQSGS-RSVSRQTRNEKQSGDGSRHSGSRHHEASSRAD 1893
Query: 1907 RTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRD 1957
+RH S++ G+ SG S ++ S S + +S ER S S SR+
Sbjct: 1894 SSRH--SQVGQGQSSG-PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 1941
Score = 82.0 bits (201), Expect = 5e-15
Identities = 109/461 (23%), Positives = 161/461 (34%), Gaps = 50/461 (10%)
Query: 1564 RNHRSPSERS-----QRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPP 1618
R H PS Q S++R HS S SH + ++ +S + RS S++ +
Sbjct: 2139 RGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTY--DK 2196
Query: 1619 ERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSH 1678
E+S G H S S RH + P R SS + H
Sbjct: 2197 EQSGDGSRHSGSHHHEASSWADSS--RHSLVGQGQSSGPRTSRPRGSSVSQ--DSDSEGH 2252
Query: 1679 RGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPS 1738
SER S S H S ++S G R H + H A S +S + + +S
Sbjct: 2253 SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSG 2312
Query: 1739 -------ERSHHSPSER---RHHSPSERSHCSPSERSHCSPSER--RHRSPSERRHHSPS 1786
E++ S ER H ++ S S S + R HR S +
Sbjct: 2313 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE 2372
Query: 1787 EKSHHSPSER-SHHSPSERRRHSPLERSRHSLLERSHRSPS---ERRSHRSFERSHRRIS 1842
S S ++ S H + + S E +R RS RS S + +H E +H R
Sbjct: 2373 GHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTG 2432
Query: 1843 ERSHSPSEKSHLSPLERSRCSPSER-----RGH--SSSG------------KTCHSPSER 1883
+ H + SR S S+ GH SSSG ++ HS S
Sbjct: 2433 TSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHH 2492
Query: 1884 SHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKY 1943
SH + G RS+ +TR+ R SG H S R+ S + +
Sbjct: 2493 SHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQG 2552
Query: 1944 SFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPEATR 1984
G R S + F + G + + + W A+R
Sbjct: 2553 QSEGPRTSRNWGSSFSQDSDSQGHSEDSER----WSGSASR 2589
Score = 80.5 bits (197), Expect = 2e-14
Identities = 96/383 (25%), Positives = 142/383 (37%), Gaps = 41/383 (10%)
Query: 1625 LSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSE--RSHRSSSERRHRSPSQRSHRGPS 1682
L E ++ S+ S S + + S E + + P + R+ + R + H S
Sbjct: 251 LEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDS 310
Query: 1683 ERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRS------HRSPSERSHHS 1736
ER S S H S ++S G R H + SH A S H S R +
Sbjct: 311 ERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTA 370
Query: 1737 PS-ERSHHSPSERR---HHSPSERSHCSPSERSHCSP--SERRHRSPSERRHHSPSEKSH 1790
S E++ SP ER H ++ S S + R S S+R HR S + S
Sbjct: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSE 430
Query: 1791 HSPSER-SHHSPSERRRHSPLERSRHSLLERSHRSPS---ERRSHRSFERSHRRISERSH 1846
+S ++ S H + R+ S E +R ERS RS S + +H + +H R +
Sbjct: 431 NSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTG 490
Query: 1847 SPSEKSHLSPLERSRCSPSER-----RGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSH 1901
H + SR S S+ RGH S + G RQG H
Sbjct: 491 GRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR--------------GGRQGS----HH 532
Query: 1902 RSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQ 1961
S R+ HS S GR+ S + RS ++ G+ HS SR +
Sbjct: 533 EQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEAS 592
Query: 1962 TTLLGTTHKNPKAGQVWRPEATR 1984
+ + H GQ P +R
Sbjct: 593 SQADSSRHSQVGQGQSSGPRTSR 615
Score = 78.6 bits (192), Expect = 6e-14
Identities = 105/410 (25%), Positives = 147/410 (35%), Gaps = 25/410 (6%)
Query: 1554 SERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSH---CSPSRKNHSSPSERSWRSPS 1610
SER + S +H S E+S+ S R H + H SRK+ + ++ S +
Sbjct: 634 SERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQA 693
Query: 1611 QRNH----CSPPER--SCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS 1664
+H S ER S H L S H S S S S + S
Sbjct: 694 ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGH 753
Query: 1665 SSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARR 1724
S + +S S G ++SH + R S+RS + H S+ SH
Sbjct: 754 SEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPS 813
Query: 1725 SHRSPSERSHHSPS-ERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHH 1783
+ + SHH + + S HS S+ + R H S R H +R H
Sbjct: 814 T--GVRQGSHHEQARDNSRHSASQ--DGQDTIRGHPGSSRRGR---QGSHHEQSVDRSGH 866
Query: 1784 SPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISE 1843
S S SH + RS S + S +R+ R S R H + SH IS
Sbjct: 867 SGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEA--SSHADISR 924
Query: 1844 RSHSPSEKSHLSPLERSRCS----PSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSER 1899
S + +S S R + S S+ GHS + + R+HR S Q R R
Sbjct: 925 HSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRG-SAQEQSRHGSR 983
Query: 1900 SHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGER 1949
RS E R SG H S + + E + S PGER
Sbjct: 984 HPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQAR-SSPGER 1032
Score = 77.4 bits (189), Expect = 1e-13
Identities = 124/516 (24%), Positives = 176/516 (34%), Gaps = 108/516 (20%)
Query: 1476 RTVQKDSSSRSKKNFYRNETSSQ----ESKNLSTPGTRVQARGRILPGSPVKRTWHRHLK 1531
R+ D S S+ N R+E +SQ ES+ G+RV R H +
Sbjct: 259 RSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQ----------DRDSEGHSE 308
Query: 1532 DKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRS-- 1589
D H G + R H +W R S + +R H S S
Sbjct: 309 DSERHS--------------GSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSR 354
Query: 1590 -----HCSPSRKNHSSPS-ERSWRSPSQRN---HCSPPERSCHSLSERGLHSP--SQRSH 1638
H S + ++ S E++ SP +R+ H + S HS + RG S S R H
Sbjct: 355 QSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGH 414
Query: 1639 RGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPS-ERSHCSPSE----RR 1693
RG S + S S ++ + Q S RG S ERS S S
Sbjct: 415 RGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVST 474
Query: 1694 HRSPSQRSHR-----GPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPS----ERSHHS 1744
H P R G + HH ++ S R A + + + R H S + SHH
Sbjct: 475 HEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQD-TIRGHPGSSRGGRQGSHHE 533
Query: 1745 PSERRH-HSPSERSHCSPSERSHCSPSERRHRSPSE--RRHHSPSEKSHHSPSERSHHSP 1801
S R HS S SH + RS S + RS S R + + HS S HH
Sbjct: 534 QSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSR--HHEA 591
Query: 1802 SERRRHSPLERSRHSLLERSHRS-PSERRSHRSFERSHRRISERSHSPSEKSHLSPLERS 1860
S S + SRHS + + S P R+ S S
Sbjct: 592 S-----SQADSSRHSQVGQGQSSGPRTSRNQGS--------------------------S 620
Query: 1861 RCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRP 1920
S+ +GHS + + R+H H S+ E++R R
Sbjct: 621 VSQDSDSQGHSEDSERWSGSASRNH---------------HGSAQEQSRDGSRHPRSHHE 665
Query: 1921 SGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSR 1956
H ++ SR+S + S SH +R
Sbjct: 666 DRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQAR 701
Score = 76.6 bits (187), Expect = 2e-13
Identities = 139/594 (23%), Positives = 211/594 (35%), Gaps = 56/594 (9%)
Query: 1407 RDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAF 1466
R ++SAD T +G+ +Q+ + G + S+ + +D+QS A
Sbjct: 1684 RHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHS------EESDTQSVSAH 1737
Query: 1467 QTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVK-RT 1525
A Q Q S ++ R+ S +ST A GR P + + R+
Sbjct: 1738 GQAGPHQ-----QSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRS 1792
Query: 1526 WHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSP 1585
H +D H + T RG H S R R S Q S++ HS
Sbjct: 1793 RHEQARDSSRHSASQEG----QDTIRG------HPGSSRGGRQGSHYEQ--SVDSSGHSG 1840
Query: 1586 SQRSHCSPSRKNHSSPSERSWRSPSQ--RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQ 1643
S SH + ++ S + RS S+ RN + S HS S S S R
Sbjct: 1841 SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQV 1900
Query: 1644 RRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHR 1703
+ S R+ R+ + S + H S+R G + R+H + + R S+
Sbjct: 1901 GQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSER-WSGSASRNHLGSAWEQSRDGSRHPGS 1959
Query: 1704 GPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR--HHSPSERSHCSP 1761
+R H S S R R S S S E++ S ER HH
Sbjct: 1960 HHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRH 2019
Query: 1762 SERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERS 1821
S H S S S + S + S S + + P ++S
Sbjct: 2020 SGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQS-------- 2071
Query: 1822 HRSPSERRSHRSFERSHRRISERS-HSPSEKSHLSPLERSRCSPSERRGH---SSSGKTC 1877
H+ + +S S RS + + S H SE +H +S S R+G + +
Sbjct: 2072 HKESARGQSGESSGRSGSFLYQVSTHEQSESTH----GQSAPSTGGRQGSHYDQAQDSSR 2127
Query: 1878 HSPSE------RSHRSPS-GMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSE 1930
HS S+ R H PS G RQG E+S +R+ HS S GR+ S +
Sbjct: 2128 HSASQEGQDTIRGHPGPSRGGRQGSHQEQS----VDRSGHSGSHHSHTTSQGRSDASRGQ 2183
Query: 1931 RSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPEATR 1984
RS ++ G+ HS S + + + H GQ P +R
Sbjct: 2184 SGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSR 2237
Score = 75.9 bits (185), Expect = 4e-13
Identities = 110/427 (25%), Positives = 149/427 (34%), Gaps = 49/427 (11%)
Query: 1554 SERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRN 1613
SER + S +H S E+S+ S R H + H + + S + + S S
Sbjct: 2256 SERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENS-SGGQ 2314
Query: 1614 HCSPPERSCHSLSER-GLH---SPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERR 1669
S E++ S ER G H S H G + S S S S S SE
Sbjct: 2315 AASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGH 2374
Query: 1670 H-----RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARR 1724
+S S GP ++SH + R S RS + H S+ +H
Sbjct: 2375 SEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTS 2434
Query: 1725 S-------HRSPSERSHHSPSERS----HHSPS---------------ERRHHSPSERSH 1758
+ H+ + S HS S+ H P +R HS S SH
Sbjct: 2435 TGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSH 2494
Query: 1759 CSPSERSHCSPSERRHRSPSE--RRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHS 1816
+ RS S RS S R + S HS S HH S R S +
Sbjct: 2495 TTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSR--HHEASSRADSSGHSQVGQG 2552
Query: 1817 LLE--RSHRSPSERRSHRSFERSHRRISER-SHSPSEKSHLSPLERSRCSPSERRGHSSS 1873
E R+ R+ S S + H SER S S S H S E+ R R H
Sbjct: 2553 QSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQED 2612
Query: 1874 GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSR 1933
+ H S S R SG R +TS +S H + G G +H ++ SR
Sbjct: 2613 -RAGHGHSADSSRQ-SGTRHTQTSSGGQAAS----SHEQARSSAGERHGSHHQQSADSSR 2666
Query: 1934 RSPLKEG 1940
S + G
Sbjct: 2667 HSGIGHG 2673
Score = 75.5 bits (184), Expect = 5e-13
Identities = 125/582 (21%), Positives = 193/582 (33%), Gaps = 84/582 (14%)
Query: 1467 QTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTW 1526
+ +S GQ + ++ SS +++ ++ S+ S++ G S V+ +
Sbjct: 2308 ENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI--------GHGQASSAVRDSG 2359
Query: 1527 HR-----HLKDKLTHKEHNHPSFYRERTPRGP-----SERTRHNPSWRNHRSPSERSQRS 1576
HR D H E + GP E TR + R+ RS S Q S
Sbjct: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 2419
Query: 1577 SLERRHHSPSQRSHCSPSRK--NHSSPSERSWRSPSQRN----HCSPPERS-------CH 1623
+ E+ + + + R+ +H + S S SQ H P S
Sbjct: 2420 THEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYE 2479
Query: 1624 SLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSH---------RSSSERRHRSPS 1674
L +R HS S SH R S RS S ++ R S R H + S
Sbjct: 2480 QLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASS 2539
Query: 1675 QRSHRGPSE----------------RSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSH 1718
+ G S+ S S+ + S G + R HH ++
Sbjct: 2540 RADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQL 2599
Query: 1719 RSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERR---HR 1775
R +R +R+ H S S R + S S E++ S ER H+
Sbjct: 2600 RDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQ 2659
Query: 1776 SPSERRHHSPSEKSHHSPSER-------SHHSPSERRRHSPLERSRHSLLERSHRSPSER 1828
++ HS S + R S S+ HS E S + ++ S +
Sbjct: 2660 QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHS--EDSDTQSVSAHGQAGSHQ 2717
Query: 1829 RSHRSFERSHRRISERS------------HSPSEKSH--LSPLERSRCSPSERRGHSSSG 1874
+SH+ E + R E S H SE SH P R R + SS
Sbjct: 2718 QSHQ--ESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 2775
Query: 1875 KTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRR 1934
+ + + R G +G H S + + HS S GR+ S + R
Sbjct: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSR 2835
Query: 1935 SPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQ 1976
S + G+ HS SR + T + H GQ
Sbjct: 2836 SASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQ 2877
Score = 75.1 bits (183), Expect = 6e-13
Identities = 160/669 (23%), Positives = 222/669 (33%), Gaps = 84/669 (12%)
Query: 1312 ESPSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQ-SLKRAFQTAH-RVIA 1369
ES ++ ++ H + G Q S R + L+Q S ++AH R
Sbjct: 3349 ESDTQSVSGH---GQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRT 3405
Query: 1370 SVGRKPVDGTRPDNLWASKNYYPKQNARDYCL--PSSIKRDKR------SADKLTPAGST 1421
S GR+ G+ + S + Q +D P S +R ++ S D+ +GS
Sbjct: 3406 STGRR--QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGS- 3462
Query: 1422 IKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKD 1481
G Q R+ S Q R D QSG + + + Q D
Sbjct: 3463 -HHSHTTSQGRSDASRGQSGSRSASRQTR-------NDEQSGDGSRHSWSHHHEASTQAD 3514
Query: 1482 SSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTW-------HRHLKDKL 1534
SS S+ + S + G+ V S W HR +
Sbjct: 3515 SSRHSQSG----QGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQ 3570
Query: 1535 THKEHNHP-SFYRERTPRGPSER------TRHNPSWRNHRSPSERSQ-RSSLERRHHSPS 1586
+ HP S + +R G S T H + ++ S Q RSS RH S
Sbjct: 3571 SRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHH 3630
Query: 1587 QRS-----HCSPSRKNHSSPSERSWRSPSQRNHCSPPE-----RSCHSLSERGLHSPSQR 1636
Q+S H SS S S + S E S+S G P Q+
Sbjct: 3631 QQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQ 3690
Query: 1637 SHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSE--RSHCSPSERRH 1694
SH+ ++ R S RS + S SE H GPS R + R
Sbjct: 3691 SHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAH------GRAGPSTGGRQGSRHEQARD 3744
Query: 1695 RSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPS 1754
S S G R H S+R R + H +RS HS S SH + R S
Sbjct: 3745 SSRHSASQEGQDTIRGHPGSRRGGRQGSY--HEQSVDRSGHSGSHHSHTTSQGR-----S 3797
Query: 1755 ERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSR 1814
+ SH RS + +S RH + ++ S HS S + + RSR
Sbjct: 3798 DASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSR 3857
Query: 1815 HSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSG 1874
S S SE S RS S S H S E+SR S G S
Sbjct: 3858 RQGSSVSQDSDSEAYPEDS--------ERRSESASRNHHGSSREQSR-DGSRHPGSSHRD 3908
Query: 1875 KTCHSPSERSHRSPSGMRQGRTSERSHRSSC--ERTRHSPSEMRPGRPSGRNHCSPSERS 1932
H S SP E H SS + HS + R S ++ SE +
Sbjct: 3909 TASHVQS-----SPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGT 3963
Query: 1933 RRSPLKEGL 1941
R + GL
Sbjct: 3964 ERQKGQSGL 3972
Score = 73.6 bits (179), Expect = 2e-12
Identities = 128/517 (24%), Positives = 181/517 (35%), Gaps = 84/517 (16%)
Query: 1467 QTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTW 1526
+++S GQ + ++ SS +++ ++ S +S +R G S V+ +
Sbjct: 1983 ESSSRGQAASSHEQARSSAGERHGSHHQLQSADS-------SRHSGIGHGQASSAVRDSG 2035
Query: 1527 HR-----HLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERR 1581
HR D H E + + GP +++ + S RS +
Sbjct: 2036 HRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVS 2095
Query: 1582 HHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGP 1641
H S+ +H S+PS R S + R HS S+ G + R H GP
Sbjct: 2096 THEQSESTH------GQSAPSTGG-RQGSHYDQAQDSSR--HSASQEG--QDTIRGHPGP 2144
Query: 1642 S----QRRHHSPS-ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRS 1696
S Q H S +RS S S SH +S R S Q R S +++ + +S
Sbjct: 2145 SRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTY-----DKEQS 2199
Query: 1697 PSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSER 1756
H G HH S S ++ S HS + S S
Sbjct: 2200 GDGSRHSGS---HHHEAS-------------SWADSSRHSLVGQGQSSGPRTSRPRGSSV 2243
Query: 1757 SHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHH-SPSERSHHSPSERRRHSPLERSRH 1815
S S SE H SERR S S H S E+S S RSHH HS E SR
Sbjct: 2244 SQDSDSE-GHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHS-AESSRQ 2301
Query: 1816 ---------------SLLERSHRSPSERR-SHRSFERSHRRISERSHSPSEKSHLSPLER 1859
S E++ S ER SH R S H + + R
Sbjct: 2302 SGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHR 2361
Query: 1860 --SRCSPSERRGHSSSGKT----CH---SPSERSHRSPSGMRQGRTSERSHRSSCERTRH 1910
S S+ GHS T H P ++SH+ + R S RS + + H
Sbjct: 2362 GSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTH 2421
Query: 1911 SPSEMRPGRP-------SGRNHCSPSERSRRSPLKEG 1940
SE GR G +H + SR S +EG
Sbjct: 2422 EQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEG 2458
Score = 59.3 bits (142), Expect = 4e-08
Identities = 79/391 (20%), Positives = 139/391 (35%), Gaps = 38/391 (9%)
Query: 1571 ERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGL 1630
E +++ +L H + SH N ++ + + PS ER + +G
Sbjct: 87 ESTRKENLPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSL------ERRNNRKGNKG- 139
Query: 1631 HSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPS 1690
+S R +RH S SE+ R +HR ++ S + + +E + +
Sbjct: 140 ---RSKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDN 196
Query: 1691 ERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSP----SERSHHSPSERSHHSPS 1746
+R + + + R + + H + + ++ + +
Sbjct: 197 RKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKI 256
Query: 1747 ERRHHSPSERSHCSPSERSHCSPSE------RRHRSPSERRHHSPSEKSHHSPSERSHHS 1800
R S +S + H + S+ R + R + H SER S
Sbjct: 257 YERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGS 316
Query: 1801 PSERRRHSPLERSRH-SLLERSHRSPSERRSH-RSFERSHRRISERSHSPSEKSHLSPLE 1858
S S E+SR S RSH +R SH S + S + + + + S S E
Sbjct: 317 ASRNHHGSAWEQSRDGSRHPRSH--DEDRASHGHSADSSRQSGTRHAETSSRGQTASSHE 374
Query: 1859 RSRCSPSERRG-----------HSSSGK--TCHSPSERSHRSPSGMRQGRTSERSHRSSC 1905
++R SP ER G HS++G+ + S+R HR SG + + S S
Sbjct: 375 QARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDT 434
Query: 1906 ER-TRHSPSEMRPGRPSGRNHCSPSERSRRS 1935
+ + H + +R ERS RS
Sbjct: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRS 465
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 96.3 bits (238), Expect = 3e-19
Identities = 139/468 (29%), Positives = 166/468 (35%), Gaps = 57/468 (12%)
Query: 1487 KKNFYRNETSSQESKNLSTPGTRVQA--RGRILPGSPVKRTWHRHLKDKLTHKEHN---- 1540
KK +E S S L V+ R R GS KR HR K KE N
Sbjct: 183 KKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRR-HRSRSSKCKRKEKNKEKK 241
Query: 1541 --HPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNH 1598
H R+ R S + H+PS +H S S R S + R S S ++
Sbjct: 242 RPHTESPGRRSHRH-SSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSP 300
Query: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHH-------SPSE 1651
S W SP QRN S H HSP + PS R +P
Sbjct: 301 SPSGGSGWGSP-QRNGGSGQRSGAHGGRPGSAHSPPDKPS-SPSPRVRDKAAAAAPTPPA 358
Query: 1652 RSHRSPSERSHRSSSERRHRSPS-------QRSHRGPSERSHCSPSERRHRSPSQRSHRG 1704
R SPS RS SS R R+ +R R S S +P R R P RG
Sbjct: 359 RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG 418
Query: 1705 PSE---RRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR--HHSPSERSHC 1759
S R S S R SER H +R+ P R SPS +H
Sbjct: 419 SSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG 478
Query: 1760 --------------SPSERSHCS---PSERRHRSPSERRHHSPSEK-SHHSPSERSHHSP 1801
P RS S PS+ R RS +E+R HSPS S P R
Sbjct: 479 RRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS-AEKRPHSPSRSPSPKKPLSRDKDGE 537
Query: 1802 SERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSR 1861
R RHS E +R RS+ +RR RRI+ P SP S
Sbjct: 538 G-RARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSS 596
Query: 1862 CSPSE--RRGHSSSGKTCHSP---SERSHRSPSGMRQ-GRTSERSHRS 1903
C S+ R HS S HS S RSH + S R RT S+ S
Sbjct: 597 CLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHS 644
Score = 81.6 bits (200), Expect = 7e-15
Identities = 126/440 (28%), Positives = 154/440 (35%), Gaps = 104/440 (23%)
Query: 1562 SWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERS 1621
S + HR +RS S +R H S+ S C KN +R H P R
Sbjct: 205 SVKKHRR--DRSDSGSRRKRRHR-SRSSKCKRKEKNKEK----------KRPHTESPGRR 251
Query: 1622 CHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRS--HR 1679
H S HSPS SH S RSPS S + E R ++ SQRS R
Sbjct: 252 SHRHSSGSSHSPSLSSHYSDS------------RSPSRLSPKHRDEGR-KTGSQRSSGSR 298
Query: 1680 GPSERSHCS-PSERRHRSPSQRS--HRGPSERRHHSPSKRSHRSP-----ARRSHRSPSE 1731
PS S +R+ QRS H G H P K S SP A + +P
Sbjct: 299 SPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPA 358
Query: 1732 RSHHSPSERSHHSPS------------ERRHHSPSERSHCSPS-------ERSHCSPSER 1772
R SPS RS S RR RS S S R +P
Sbjct: 359 RGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG 418
Query: 1773 RHRSPSERRHHSPSEKSHHSP-------SERSHHSPSERRRHSPLERSRHSLLERS---- 1821
RS S R S S +P SER H +R + P R+R + S
Sbjct: 419 SSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERP-PRARPASTSPSPGAH 477
Query: 1822 -HRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSP 1880
R E +S H R S SPS +SR +E+R HS S SP
Sbjct: 478 GRRGGPEGKSSSRSPGPHPRSWSSSRSPS---------KSRSRSAEKRPHSPSRSP--SP 526
Query: 1881 SERSHRSPSGMRQGRTSE----------RSHRSSCERTRHSPSEMRPGR----------- 1919
+ R G + R SE RS+ +R R SPS M P R
Sbjct: 527 KKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPY 586
Query: 1920 ----PSGRNHCSPSERSRRS 1935
PS + C S+ S RS
Sbjct: 587 YRPSPSSSSSCLSSDYSTRS 606
Score = 80.5 bits (197), Expect = 2e-14
Identities = 106/401 (26%), Positives = 135/401 (33%), Gaps = 48/401 (11%)
Query: 1581 RHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHR- 1639
+H S S S +K RS + + CS C S S S + HR
Sbjct: 157 KHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECS-----CGSSSPLRKKKKSVKKHRR 211
Query: 1640 -----GPSQRRHHSPSERSHRSPSERSHRSSSERRHR--SPSQRSHRGPSERSHCSPSER 1692
G ++R H RS S +R ++ ++R SP +RSHR S SH SPS
Sbjct: 212 DRSDSGSRRKRRH----RSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSH-SPSLS 266
Query: 1693 RHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHS 1752
H S S+ R + R S RS RS SP H
Sbjct: 267 SHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGG 326
Query: 1753 PSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSER-------- 1804
+H P + S SP R R + +P + SPS RS S R
Sbjct: 327 RPGSAHSPPDKPSSPSP---RVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGA 383
Query: 1805 -RRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCS 1863
RR R R S RS S RR R + R S RS S + S S R
Sbjct: 384 GRRRRRRRRRRRS---RSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPG 440
Query: 1864 PS----ERRGHSSSGKTCHSPSERSH---RSPSGMRQGRTSERSHRSSCERTRHSPSEMR 1916
P RGH GK R+ SPS GR +SS P
Sbjct: 441 PGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWS 500
Query: 1917 PGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRD 1957
R ++ +E+ SP + P LSRD
Sbjct: 501 SSRSPSKSRSRSAEKRPHSPSR--------SPSPKKPLSRD 533
Score = 68.6 bits (166), Expect = 6e-11
Identities = 91/311 (29%), Positives = 118/311 (37%), Gaps = 40/311 (12%)
Query: 1676 RSHRGPSER----SHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSE 1731
R HRG + S SP ++ + R +RR S SP R+ +S +
Sbjct: 149 RGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKK 208
Query: 1732 RSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHH 1791
H S +RRH S S S C E++ +R H RR H S S H
Sbjct: 209 ---HRRDRSDSGSRRKRRHRSRS--SKCKRKEKN--KEKKRPHTESPGRRSHRHSSGSSH 261
Query: 1792 SPSERSHHSPSER-RRHSPLER--SRHSLLERS--HRSP---------SERRSHRSFERS 1837
SPS SH+S S R SP R R + +RS RSP S +R+ S +RS
Sbjct: 262 SPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRS 321
Query: 1838 --HRRISERSHSPSEK-SHLSPLERSRC-----SPSERRGHSSSGKTCHSPSERSHRSPS 1889
H +HSP +K S SP R + +P R S S ++ S R R+
Sbjct: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAG 381
Query: 1890 G----MRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSF 1945
G R+ R RS S+ R RP P G S S RS G
Sbjct: 382 GAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRG---SSRSLSRARSSSDSGSGRGA 438
Query: 1946 PGERPSHSLSR 1956
PG P R
Sbjct: 439 PGPGPEPGSER 449
Score = 65.9 bits (159), Expect = 4e-10
Identities = 140/591 (23%), Positives = 207/591 (35%), Gaps = 90/591 (15%)
Query: 1216 DLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKR 1275
D GP P Y RG R +TK H+ + P+ + +R
Sbjct: 133 DDDDGPVDCDCPASCY--RGHRGY-----RTK-----HWSSSSASPPPKKKKKKKGGHRR 180
Query: 1276 AKVRTKKTSD----SKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQ 1331
++ + + S+ S P+++ K ++KHR+ ++S + RRKR ++
Sbjct: 181 SRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGS-------------RRKRRHRSR 227
Query: 1332 TSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASKNYY 1391
+S K + K+ +P +S + + ++H S+ D P L
Sbjct: 228 SSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHS--PSLSSHYSDSRSPSRL------S 279
Query: 1392 PKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRP 1451
PK RD + +R S GS WG + + Q A+ +P
Sbjct: 280 PKH--RDEGRKTGSQRSSGSRSPSPSGGSG-------WGSPQRNGGSGQRSGAHGGRPGS 330
Query: 1452 LRLP--KPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTR 1509
P KP+ + + A+ K+S S R+ SSQ + G
Sbjct: 331 AHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSP------RSAPSSQGRGGRAAGGAG 384
Query: 1510 VQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE---RTRHNPSWRNH 1566
+ R R +R R + P R PRG S R R + +
Sbjct: 385 RRRRRRR------RRRRSRSSASAPRRRGRRRP---RPAPPRGSSRSLSRARSSSDSGSG 435
Query: 1567 RSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLS 1626
R ER H +R+ P R +S S SP PE S S
Sbjct: 436 RGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSP----SPGAHGRRGGPEGKSSSRS 491
Query: 1627 ERGLHSPSQRSHRGPSQRRHHSPSERSH---RSPSERSHRSSSE----RRHRSPSQRSHR 1679
G H S S R PS+ R S +R H RSPS + S + R S ++ +
Sbjct: 492 P-GPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRA 550
Query: 1680 GPSERSHCSPSERRHRSPS-QRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPS 1738
RS+ +RR SPS R S R+ P R S + S HS S
Sbjct: 551 RRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRS 610
Query: 1739 ERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKS 1789
HS H S S RSH + S SPS R+PS H S +S
Sbjct: 611 PSPGHS-----HGSYSSRSHGTRSRTR--SPS----RTPSPSYHSRSSSES 650
Score = 65.5 bits (158), Expect = 5e-10
Identities = 97/321 (30%), Positives = 114/321 (35%), Gaps = 65/321 (20%)
Query: 1550 PRGPSERTRHN-------PSWRNHRSPSERSQRSSLERRHHSPS-------QRSHCSPSR 1595
P PS R R P R SPS RS SS R + +R SR
Sbjct: 338 PSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSR 397
Query: 1596 KNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSH- 1654
+ S+P R R P +PP S SLS R S S RG SER H
Sbjct: 398 SSASAPRRRGRRRPRP----APPRGSSRSLS-RARSSSDSGSGRGAPGPGPEPGSERGHG 452
Query: 1655 ---RSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHH 1711
+ ER R+ SP RG E S S H S S R PS+ R
Sbjct: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPR-SWSSSRSPSKSRSR 511
Query: 1712 SPSKRSH---RSPARRSHRSPSE----RSHHSPSE--------RSHHSPSERRHHSPSER 1756
S KR H RSP+ + S + R+ HS +E RS+ +RR SPS
Sbjct: 512 SAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFM 571
Query: 1757 S---------------HCSPSERSHCSPSERRHRSPSERRHHSPSE--KSHHSPSERSH- 1798
SPS S C S+ S R H SH S S RSH
Sbjct: 572 EPRRITSARKRPIPYYRPSPSSSSSCLSSDY-----STRSHSRSPSPGHSHGSYSSRSHG 626
Query: 1799 ---HSPSERRRHSPLERSRHS 1816
+ S R SP SR S
Sbjct: 627 TRSRTRSPSRTPSPSYHSRSS 647
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 95.9 bits (237), Expect = 3e-19
Identities = 101/348 (29%), Positives = 142/348 (40%), Gaps = 36/348 (10%)
Query: 1546 RERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERS 1605
++R+ ERTRH + + E + + R S ++ SPS+++ S R
Sbjct: 181 KKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTT--RSKSKERKKSKSPSKRSKSQDQARK 238
Query: 1606 WRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSE-RSHRS 1664
+SP+ R S ++ + + + S+ R SP RS + RS
Sbjct: 239 SKSPTLRRRSQEKIGKARSPTDDKV----KIEDKSKSKDRKKSPIINESRSRDRGKKSRS 294
Query: 1665 SSERRHRSPSQRSH--RGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPA 1722
+ R +S +RS S+RS ++ +SPS+ + G R SPS+R RSP
Sbjct: 295 PVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENR---SPSRRPGRSPK 351
Query: 1723 RRS-HRSPSERSHHSPS-----ERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRS 1776
RRS P ++S S S RS S S R SP R+ ER P RR S
Sbjct: 352 RRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSS 411
Query: 1777 PSER----------RHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPS 1826
P R R S + SP+ R SP RR SPL RSR R RSP
Sbjct: 412 PRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSP--RRRSRSPR 469
Query: 1827 ERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSG 1874
R R RS R+ RS S + S RS+ + +G S G
Sbjct: 470 RRDRGR---RSRSRLRRRSRSRGGRRRRS---RSKVKEDKFKGSLSEG 511
Score = 91.7 bits (226), Expect = 7e-18
Identities = 126/519 (24%), Positives = 192/519 (36%), Gaps = 77/519 (14%)
Query: 1480 KDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEH 1539
+D++S N E S +S+N + + + + R K H+H ++ K+H
Sbjct: 16 EDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRS------KHKKHKHSSEEDKDKKH 69
Query: 1540 NHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKN-- 1597
H +++ + + S + SP++R++ L QR+ N
Sbjct: 70 KHKHKHKKH-----KRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDNEL 124
Query: 1598 ---------------HSSPSER--------------SWRSPSQR-------NHCSPPERS 1621
+ S SE S RS S + N + +RS
Sbjct: 125 MEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRS 184
Query: 1622 CHSLSERGLHSPSQRSHRGPSQ------RRHHSPSERSHRSPSERSHRSSSERRHRSPSQ 1675
ER H ++ +G + R S + +SPS+RS R+ +SP+
Sbjct: 185 KSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSPTL 244
Query: 1676 RSHRGPSERSHCSPSERR----HRSPSQRSHRGP--SERRHHSPSKRSHRSPARRSHRSP 1729
R SP++ + +S S+ + P +E R K+S RSP +S
Sbjct: 245 RRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKS-RSPVDLRGKSK 303
Query: 1730 SERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERR-HHSPSEK 1788
RS S +S S +++ S + S + + SPS R RSP R P +K
Sbjct: 304 DRRSR-SKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDK 362
Query: 1789 SHHSPS-----ERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISE 1843
S S S RS S S R SP R++ LER R P RR R I
Sbjct: 363 SRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILS 422
Query: 1844 RSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRS 1903
R + S ++ R SP+ RR S + SP RS R R +R RS
Sbjct: 423 RRERSKDASPIN-----RWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRGRRS 477
Query: 1904 SCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLK 1942
R S S R GR R+ E + L EG+K
Sbjct: 478 RSRLRRRSRS--RGGR-RRRSRSKVKEDKFKGSLSEGMK 513
Score = 73.2 bits (178), Expect = 2e-12
Identities = 109/393 (27%), Positives = 153/393 (38%), Gaps = 71/393 (18%)
Query: 1475 LRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKL 1534
LR KD SRSK+ + + +E K + +P KD
Sbjct: 298 LRGKSKDRRSRSKERKSKRSETDKEKKPIKSPS-----------------------KDAS 334
Query: 1535 THKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPS 1594
+ KE+ PS R+P+ S + R RSP +RS ++ SPS+ SP
Sbjct: 335 SGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRS---KQSKSPSRT--LSPG 389
Query: 1595 RKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSP--SQRSHRGPSQRRHHSPSER 1652
R+ S ER R P +R SP R + R S S + P++RR SP R
Sbjct: 390 RRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRR 449
Query: 1653 SHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHS 1712
RSP RS S RR RSP +R RG RR RS +R R RR S
Sbjct: 450 RSRSPLRRSR--SPRRRSRSPRRRD-RG-----------RRSRSRLRRRSRSRGGRRRRS 495
Query: 1713 PSK-RSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSE 1771
SK + + S E+ S E + E+
Sbjct: 496 RSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQ--------------R 541
Query: 1772 RRHRSPSERRHHSPSEKSHHS-PSERSHHSPSERRRHSPLERSRHSLLER--SHRSPSER 1828
R R +++ +E S+ S PSE S S R R SP S +LER + ER
Sbjct: 542 RIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTR-SP---SPDDILERVAADVKEYER 597
Query: 1829 RSHRSFERS----HRRIS-ERSHSPSEKSHLSP 1856
+ +FE S H ++ E+++ S+K L+P
Sbjct: 598 ENVDTFEASVKAKHNLMTVEQNNGSSQKKLLAP 630
Score = 47.0 bits (110), Expect = 2e-04
Identities = 99/427 (23%), Positives = 154/427 (36%), Gaps = 52/427 (12%)
Query: 1271 QNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAAH--------- 1321
+++ R+K RT+ SD K I K + + R +SPS+ +
Sbjct: 183 RSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSKSP 242
Query: 1322 -LRRK---RIGATQTST-ASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPV 1376
LRR+ +IG ++ T +K + K S+ + + ++ R R PV
Sbjct: 243 TLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIIN------ESRSRDRGKKSRSPV 296
Query: 1377 D--GTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQ 1434
D G D SK K++ D K+ +S K +G + G + +
Sbjct: 297 DLRGKSKDRRSRSKERKSKRSETD-----KEKKPIKSPSKDASSGKENRSPSRRPGRSPK 351
Query: 1435 CRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNE 1494
RS R S + R L QS +T S G+ R+K +
Sbjct: 352 RRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGR-----------RAKSRSLERK 400
Query: 1495 TSSQESKNLSTPGTR-----VQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERT 1549
E + LS+P TR + R R SP+ R + + + + R R+
Sbjct: 401 RREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRS 460
Query: 1550 PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQ-RSHCSPSRKNHSSPSERSWRS 1608
PR S R R RS R RS RR S S+ + + E+ S
Sbjct: 461 PRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSS 520
Query: 1609 PSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRS-PSERSHRSSSE 1667
E +L E+ +R R +++ +E S+ S PSE S SS
Sbjct: 521 DDNLEDFDVEEEDEEALIEQ------RRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSST 574
Query: 1668 RRHRSPS 1674
R RSPS
Sbjct: 575 RT-RSPS 580
Score = 37.0 bits (84), Expect = 0.19
Identities = 41/173 (23%), Positives = 81/173 (46%), Gaps = 12/173 (6%)
Query: 1184 RDRPVIRRSPISPSQRKAKIYTQASKSPTSTIDLQS----GPSQSPAPVQVYI----RRG 1235
R + R+ SPS+R +K QA KS + T+ +S G ++SP +V I +
Sbjct: 214 RSKSKERKKSKSPSKR-SKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSK 272
Query: 1236 QRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITK 1295
R + ++ ++++R G + V +S +++++R K + +T K P+K +K
Sbjct: 273 DRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKER-KSKRSETDKEKKPIKSPSK 331
Query: 1296 RLRKHRKFYTNSRTTIESPSRELAAHLRRKRIGATQTSTASLKR--QPKKPSQ 1346
++ + SR SP R + R + +++ + +R Q K PS+
Sbjct: 332 DASSGKENRSPSRRPGRSPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSR 384
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 95.5 bits (236), Expect = 5e-19
Identities = 117/534 (21%), Positives = 191/534 (35%), Gaps = 79/534 (14%)
Query: 1474 PLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDK 1533
P V+K+ R K + + +SS + + + + K+ +H K+
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238
Query: 1534 LTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSP 1593
HK +E+ R S++ S S S+ +LE + S + P
Sbjct: 239 RKHK--------KEKKKRKKSKK-----------SASSESEAENLEAQPQSTVRPEEIPP 279
Query: 1594 SRKNH---------SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQR 1644
+N + ER R + C+PP S R L + S R +G R
Sbjct: 280 IPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPR 339
Query: 1645 RHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSER------SHCSPSERRHRSPS 1698
R+ +PS R RS R+ +QR ER S + + RSP
Sbjct: 340 RYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPV 399
Query: 1699 QRSHRGPSERRH--HSPSKRSHRSPARRSHRSPSE------------------------R 1732
+ R ++ R+ SP++++ + + H+S S+ +
Sbjct: 400 RVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSK 459
Query: 1733 SHHSPSERSHHSPSERRHHSPSERSHCSPSE-RSHCSPSERRHRSPS-----ERRHHSPS 1786
S E+S + +H+ E+ S S+ R H + E+ +S S ER
Sbjct: 460 SRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK 519
Query: 1787 EKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSH-RRISERS 1845
K S S HS S+ + RSR + + S + R RS R RR+ R+
Sbjct: 520 SKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRT 579
Query: 1846 HSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSC 1905
H ++S R R RRG S S R R+P G + R+ +R R
Sbjct: 580 HD-RDRSRSKEYHRYREQEYRRRGRSRS---------RERRTPPG--RSRSKDRRRRRRD 627
Query: 1906 ERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFK 1959
R+ + RN S S + + E YS + S + SR+ K
Sbjct: 628 SRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKK 681
Score = 85.9 bits (211), Expect = 4e-16
Identities = 130/564 (23%), Positives = 208/564 (36%), Gaps = 78/564 (13%)
Query: 1458 TDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNE-----------------TSSQES 1500
+DS S Q++S + ++ S + KK +N +S E+
Sbjct: 202 SDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEA 261
Query: 1501 KNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGP------- 1553
+NL + R +P P R R K KE + RER P
Sbjct: 262 ENLEAQ-PQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASY 320
Query: 1554 --------SERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERS 1605
S R R +R+PS R R P R +++ S ER
Sbjct: 321 QRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERW 380
Query: 1606 WRSP-SQRNHCSPPERSCHSLSERGL-------HSPSQRSHRGPSQRRHHSPS-ERSHRS 1656
+ S+ N +RS + ER + SP++++ + + H S S ER R
Sbjct: 381 IKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRR 440
Query: 1657 PSERSHRSSSERRHRSPS-------QRSHRGPSERSHCSPSERRHRSPSQ-RSHRGPSER 1708
SE+ + ++ + R+ S ++S + H E+R RS S+ R H E+
Sbjct: 441 NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEK 500
Query: 1709 RHHSPSKRSHRSPARRSHRSP------SERSHHSPSERSHHSPSERRHHSPSERSHCSPS 1762
S SK + +R +S +E H E+ + S R ++ H S
Sbjct: 501 EKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNS 560
Query: 1763 ---ERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLE 1819
ERS RR RS + R S S K +H E+ + RRR R R +
Sbjct: 561 RTRERSRSRDRSRRVRSRTHDRDRSRS-KEYHRYREQEY-----RRRGRSRSRERRTPPG 614
Query: 1820 RSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHS 1879
RS RS RR R S R E S S ++ + + +S S R+ +S S K +S
Sbjct: 615 RS-RSKDRRRRRRDSRSSER---EESQSRNKDKYRNQESKS----SHRKENSESEKRMYS 666
Query: 1880 PSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKE 1939
S R H S + R+ + S + +E++ + E+ R S KE
Sbjct: 667 KS-RDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKE----DEKIRSSVEKE 721
Query: 1940 GLKYSFPGERPSHSLSRDFKNQTT 1963
K H ++ F ++++
Sbjct: 722 NQKSKGQENDHVHEKNKKFDHESS 745
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 94.7 bits (234), Expect = 8e-19
Identities = 100/379 (26%), Positives = 144/379 (37%), Gaps = 34/379 (8%)
Query: 1567 RSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLS 1626
RS + +RS RH + S ++ H + +E +S + +R
Sbjct: 660 RSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEE--KSSKAESGEKSKKRKKRKRK 717
Query: 1627 ERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSH 1686
+ +P+ S RGP + P S P R +R P++ G +
Sbjct: 718 KNKSSAPAD-SERGP---KPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGG 773
Query: 1687 CSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHH-SP 1745
S + H + PS + + +KRS RS R S E S + S R H SP
Sbjct: 774 GGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSP 833
Query: 1746 SERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRH--HSPSEKSHHSPSERSHHSPSE 1803
S+ +S E S SE S R RS S RRH H S +S+ S S+ S
Sbjct: 834 SQ---YSEEEEEEDSGSEHS-------RSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCY 883
Query: 1804 RRRHSPLERSRHSLLERSHRSPSERRSHRS----FERSHRRISERSHSPSEKSHLSPLER 1859
R+ S + S +RS R +RSH S + S R +S S+ + +
Sbjct: 884 SRQRSYSDDSYSDYSDRSRR--HSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQ 941
Query: 1860 SRC-------SPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSP 1912
SR S RG S S S S+R RS + R+ RS+ R+ SP
Sbjct: 942 SRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRS--RSYSRDRSRSTRSP 999
Query: 1913 SEMRPGRPSGRNHCSPSER 1931
S+ R H SP ER
Sbjct: 1000 SQRSGSRKRSWGHESPEER 1018
Score = 84.0 bits (206), Expect = 1e-15
Identities = 115/432 (26%), Positives = 167/432 (38%), Gaps = 40/432 (9%)
Query: 1476 RTVQKDSSSRSKKNFYRNETSSQESKNL-STPGTRVQARGRILPGSPVKRTWHRHLKDKL 1534
++ + +S +SKK R ++ S S G + + G P P +R R +D
Sbjct: 698 KSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRR---RRAQD-- 752
Query: 1535 THKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPS 1594
+ S E G + S ++H + + + + ++RS S
Sbjct: 753 ---DSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSH 809
Query: 1595 RKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRH--HSPSER 1652
R SS E S + S R H P + E S RS R S RRH H S R
Sbjct: 810 RSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRS-RSRSGRRHSSHRSSRR 868
Query: 1653 SHRSPSERSHRSSSERRHRSPSQRSH-------RGPSERSHCSP----SERRHRSPSQRS 1701
S+ S S+ S S R RS S S+ R S+RSH S + +HRS +
Sbjct: 869 SYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRS---KR 925
Query: 1702 HRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSP 1761
H+ S +S S RS +R R S S S S S+RR S S +H
Sbjct: 926 HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRR--SRSTTAHSWQ 983
Query: 1762 SERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERS 1821
RS+ R RSPS+R H SP ER HS S + RS+ RS
Sbjct: 984 RSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEER--HSGRRDFIRSKIYRSQSPHYFRS 1041
Query: 1822 HR--SPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSR--CSPSERRGHSSSGKTC 1877
R P ++ R + S+ + PS+ S++ S CSP ++ ++
Sbjct: 1042 GRGEGPGKKDDGRGDD------SKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLLLE 1095
Query: 1878 HSPSERSHRSPS 1889
S + R PS
Sbjct: 1096 KIQSRKVERKPS 1107
Score = 82.8 bits (203), Expect = 3e-15
Identities = 131/565 (23%), Positives = 213/565 (37%), Gaps = 58/565 (10%)
Query: 1436 RSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNET 1495
+ A++ S QP+ + +P++ S + A +G + +S S+ E+
Sbjct: 452 QGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKA-LGGDVSDQSLESHSQKVSETQMCES 510
Query: 1496 SSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE 1555
+S + +L+TP + G P P + KD+ T + PS T PS
Sbjct: 511 NSSKETSLATPAGKESQEG---PKHPTGPFFPVLSKDESTALQW--PSELLIFTKAEPSI 565
Query: 1556 RTRHNPSWRNHRSPSERSQRS--SLERRHHSPSQRSHCS---PSRKNHSSP--SERSWRS 1608
NP + + + + R+ + + + S + H P N S E+ RS
Sbjct: 566 SYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRS 625
Query: 1609 PSQRNHCSPPERSCHSLSER---GLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSS 1665
R +C L+++ G H S+ G S S +SHR ++ H+ S
Sbjct: 626 SGGRMDAPASGSACSGLNKQEPGGSHG-SETEDTGRSLPSKKERSGKSHRHKKKKKHKKS 684
Query: 1666 SE--RRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSER--RHHSPSKRSHRSP 1721
S+ R+H++ ++ ++R R ++ S SER + P S P
Sbjct: 685 SKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPP 744
Query: 1722 ARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERR 1781
RR + P+E + S + H + PS + R+ ++R
Sbjct: 745 RRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRS 804
Query: 1782 HHSPSEKSHHSPSERSHHSPSERRRH--SPLERSRHSLLERS------HRSPSERR--SH 1831
S S +S S + S R H SP + S E S RS S RR SH
Sbjct: 805 SRS-SHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSH 863
Query: 1832 RSFERSHRRISE---------RSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSE 1882
RS RS+ S+ R S S+ S+ +RSR +R H S S
Sbjct: 864 RSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSR--RHSKRSHDSDDSDYASSKH 921
Query: 1883 RSHRSPSGMRQGRTSERSHRSSCERTR-----HSPSEMRPGRPSGRNHCSPSERSRRSPL 1937
RS R + +S+ + SC ++R H+ R S + CS S RRS
Sbjct: 922 RSKR-----HKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRS-- 974
Query: 1938 KEGLKYSFPGERPSHSLSRDFKNQT 1962
+ +S+ + S S SRD T
Sbjct: 975 RSTTAHSW---QRSRSYSRDRSRST 996
Score = 41.6 bits (96), Expect = 0.008
Identities = 63/233 (27%), Positives = 93/233 (39%), Gaps = 35/233 (15%)
Query: 1554 SERTRHNPSWRNHRSPSERSQRSSLERRH-HSPSQRSH---CSPSR---KNHSSPSERSW 1606
S+R+R + + S+ + +RH +S S + CS SR ++H+ RS
Sbjct: 898 SDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRS- 956
Query: 1607 RSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSS 1666
R S+ + CS S S+R S S +H R + RS RSPS+RS S
Sbjct: 957 RGRSRSSSCS------RSRSKR--RSRSTTAHSWQRSRSYSRDRSRSTRSPSQRS---GS 1005
Query: 1667 ERR---HRSPSQR-SHRGPSERSHCSPSERRHRSPSQRSH--------RGPSERRHHSPS 1714
+R H SP +R S R RS S+ H S R RG + PS
Sbjct: 1006 RKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPS 1065
Query: 1715 KRSHRSPARRSHRSPSERSHHSPSER----SHHSPSERRHHSPSERSHCSPSE 1763
+ S+ R S S +S + + S R S SE +P++
Sbjct: 1066 QNSNIGTGRGSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNK 1118
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 92.8 bits (229), Expect = 3e-18
Identities = 156/811 (19%), Positives = 305/811 (37%), Gaps = 112/811 (13%)
Query: 1211 PTSTIDLQSG--PSQSPAPVQVYIRRG-----QRSRPDLVEKTKTRAPGHYEFTQVHNLP 1263
P I L SG P + P +++ ++ + S+P ++ H T H P
Sbjct: 121 PFDHIVLHSGQRPPELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAP 180
Query: 1264 ESDSESTQNE-KRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSRELAAHL 1322
+ E++ N+ K +R +++ D ++ T ES ++
Sbjct: 181 PTSEENSSNQGKDPMIRNQRSVDPA-----------------DSTTTHKESAGKKHITPA 223
Query: 1323 RRKRIGATQTST--ASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTR 1380
+ +I +++T +++ R+ K +P ++ +L + ++H+ S T+
Sbjct: 224 PKSKINCRKSTTGKSTVTRKSDKTGRP--LEKSMSTLDKTSTSSHKTTTSFHNSGNSQTK 281
Query: 1381 ------PDNLWA-SKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTV 1433
P+ + A SK Y + + R ++DKL + QE I
Sbjct: 282 QKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELT 341
Query: 1434 QCRSAQQPRRAYSFQPRPLRLP-KPTDSQSGIAFQ--TASVGQPLRTVQKDSSSRS---- 1486
Q + + P +PT+++ A + T S +P ++ ++ +
Sbjct: 342 QSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFP 401
Query: 1487 -----KKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWH-RHLKDKLTHKEHN 1540
+ NE ++ + G R A P SP + T H ++ T
Sbjct: 402 AGPTENREMTANENTTLFPAEPTEHGERT-ANENTTP-SPAEPTEHGERTANENTTPSPA 459
Query: 1541 HPSFYRERTP-------RGPSERTRHN---PSWRNHRSPSERSQRSSLERRHHSPSQRSH 1590
P+ + ERTP +E T H P + +PS + ER + + S
Sbjct: 460 EPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSP 519
Query: 1591 CSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPS 1650
P+ ++ +E++ SP + P E + +E+ SP++ + G + +
Sbjct: 520 AGPTENRETTANEKTTLSPVE-----PTENRETTANEKTTPSPAEPTENGQRTPFANEKT 574
Query: 1651 ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRH 1710
S P+E R+ + +PS P+E P+E R R+ ++++ P+E
Sbjct: 575 TSSSAEPTEHGERTPLANENTTPS------PAE-----PTENRERTANEKTTPSPAE--- 620
Query: 1711 HSPSKRSHRSPARRSHRSPS-----ERSHHSP-----SERSHHSPSERRHHSPSERSHCS 1760
P++ R+P +PS E +P + S P+E +P + +
Sbjct: 621 --PTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTT 678
Query: 1761 PSERSHCSPSERRHRSPSERRHHSPS---EKSHHSPSERSHHSPSERRRHSPLERSRHSL 1817
PS P+E R R+ +E SP+ E + +E++ P+E + ER+ +
Sbjct: 679 PSP---AEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENR--ERTANEK 733
Query: 1818 LERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLER-----SRCSPSERRGHSS 1872
S P+E F ++ + + S P+E +PL S P+E R ++
Sbjct: 734 TTSSPAEPTENGQRTPF--ANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTA 791
Query: 1873 SGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERS 1932
+ KT P+E P+ R+ +E + S + T + + + P+E
Sbjct: 792 NEKTTPFPAE-----PTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENG 846
Query: 1933 RRSPLKEGLKYSFPGERPSHSLSRDFKNQTT 1963
+R+P S E H+ N+ T
Sbjct: 847 KRTPFANEKTTSSSAEPTEHAERTPLANENT 877
Score = 90.9 bits (224), Expect = 1e-17
Identities = 116/560 (20%), Positives = 220/560 (39%), Gaps = 89/560 (15%)
Query: 1437 SAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSS-SRSKKNFYRNET 1495
++Q +++ SF + K T +G ++ TV D +++ KN +
Sbjct: 277 NSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETIS 336
Query: 1496 SSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE 1555
+++ +++L+ P + GR T E+N PS P E
Sbjct: 337 ANELTQSLAEP---TEHGGR-------------------TANENNTPS---PAEPTENRE 371
Query: 1556 RTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSS------PSERSWRSP 1609
RT + + + P+E +R++ E P+ + N ++ P+E R+
Sbjct: 372 RTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTA 431
Query: 1610 SQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERR 1669
++ SP E + E G + ++ + P++ H + S S+E
Sbjct: 432 NENTTPSPAEPT-----EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHG 486
Query: 1670 HRSPSQRSHRGPSERSHCSPSERRHRSPSQR---SHRGPSERRHHSPSKRSHRSPARRSH 1726
R+P + PS P+E R R+ ++ S GP+E R + ++++ SP +
Sbjct: 487 ERTPLANENTTPSP---AEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTE 543
Query: 1727 R---SPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPS----- 1778
+ +E++ SP+E + + + + S P+E +P + +PS
Sbjct: 544 NRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPT 603
Query: 1779 ERRHHSPSEKSHHSPSERSHHSPSERRRHSPL--ERSRHSLLERSHRSPSERRSHRSFER 1836
E R + +EK+ SP+E P+E +PL E++ SL E P+E F
Sbjct: 604 ENRERTANEKTTPSPAE-----PTENGDRTPLANEKTTPSLAE-----PTENGQRTPF-- 651
Query: 1837 SHRRISERSHSPSEKSHLSPLERSRCSPS-----ERRGHSSSGKTCHSPS------ERSH 1885
++ + + S P+E +PL +PS E R +++ T SP+ E +
Sbjct: 652 ANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTA 711
Query: 1886 RSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSF 1945
+ + +E R++ E+T SP+E P+E +R+P S
Sbjct: 712 NEKTTLFPAEPTENRERTANEKTTSSPAE-------------PTENGQRTPFANEKTTSS 758
Query: 1946 PGERPSHSLSRDFKNQTTLL 1965
E H N+ T L
Sbjct: 759 SAEPTEHGERTPLANENTTL 778
Score = 83.2 bits (204), Expect = 2e-15
Identities = 104/497 (20%), Positives = 193/497 (38%), Gaps = 74/497 (14%)
Query: 1476 RTVQKDSSSRSKKNFYRNETSSQESKNLS------TPGTRVQARGRILPGSPVKRTWHRH 1529
RT ++++ ET++ E LS T + P P +
Sbjct: 509 RTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTP 568
Query: 1530 LKDKLTHKEHNHPSFYRERTPRG-------PSERTRHNPSWRNHRS------PSERSQRS 1576
++ T P+ + ERTP P+E T + N ++ P+E R+
Sbjct: 569 FANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRT 628
Query: 1577 SLERRHHSPS--------QRSHCSPSRKNHSS--PSERSWRSPSQRNHCSPPERSCHSLS 1626
L +PS QR+ + + SS P+E R+P + +P
Sbjct: 629 PLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENR 688
Query: 1627 ERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSH 1686
ER + + S GP++ R + +E++ P+E +E R R+ ++++ P+E
Sbjct: 689 ERTANENTTPSPAGPTENREMTANEKTTLFPAE-----PTENRERTANEKTTSSPAE--- 740
Query: 1687 CSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPS 1746
P+E R+P S P++ R+P +E + SP+ P+
Sbjct: 741 --PTENGQRTPFANEKTTSSSA---EPTEHGERTPL------ANENTTLSPA-----GPT 784
Query: 1747 ERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRR 1806
E R + +E++ P+E P+E R R+ +E SP++ P+E +P +
Sbjct: 785 ENRERTANEKTTPFPAE-----PTENRERTANENTTPSPAQ-----PTENGDRTPLANEK 834
Query: 1807 HSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSE 1866
+P S E R+P S +ER+ +E + SP E P+E
Sbjct: 835 TTP---SLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAE-----PTE 886
Query: 1867 RRGHSSSGKTCHSPSERSHRSPSGMRQGRTS-ERSHRSSCERTRHSPSEMRPGRPSGRNH 1925
R +++ KT P+E + S + T + E T + + + P P+
Sbjct: 887 NRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEE 946
Query: 1926 CSP--SERSRRSPLKEG 1940
+P + + ++P ++G
Sbjct: 947 MTPLMVDENLQAPFRQG 963
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 89.7 bits (221), Expect = 2e-17
Identities = 116/560 (20%), Positives = 219/560 (39%), Gaps = 89/560 (15%)
Query: 1437 SAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSS-SRSKKNFYRNET 1495
++Q +++ SF + K T +G ++ TV D +++ KN +
Sbjct: 215 NSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETIS 274
Query: 1496 SSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE 1555
+++ +++L+ P + GR T E+N PS P E
Sbjct: 275 ANELTQSLAEP---TEHGGR-------------------TANENNTPS---PAEPTENRE 309
Query: 1556 RTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSS------PSERSWRSP 1609
RT + + + P E +R++ E P+ + N ++ P+E R+
Sbjct: 310 RTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTA 369
Query: 1610 SQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERR 1669
++ SP E + E G + ++ + P++ H + S S+E
Sbjct: 370 NENTTPSPAEPT-----EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHG 424
Query: 1670 HRSPSQRSHRGPSERSHCSPSERRHRSPSQR---SHRGPSERRHHSPSKRSHRSPARRSH 1726
R+P + PS P+E R R+ ++ S GP+E R + ++++ SP +
Sbjct: 425 ERTPLANENTTPSP---AEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTE 481
Query: 1727 R---SPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPS----- 1778
+ +E++ SP+E + + + + S P+E +P + +PS
Sbjct: 482 NRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPT 541
Query: 1779 ERRHHSPSEKSHHSPSERSHHSPSERRRHSPL--ERSRHSLLERSHRSPSERRSHRSFER 1836
E R + +EK+ SP+E P+E +PL E++ SL E P+E F
Sbjct: 542 ENRERTANEKTTPSPAE-----PTENGDRTPLANEKTTPSLAE-----PTENGQRTPF-- 589
Query: 1837 SHRRISERSHSPSEKSHLSPLERSRCSPS-----ERRGHSSSGKTCHSPS------ERSH 1885
++ + + S P+E +PL +PS E R +++ T SP+ E +
Sbjct: 590 ANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTA 649
Query: 1886 RSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSF 1945
+ + +E R++ E+T SP+E P+E +R+P S
Sbjct: 650 NEKTTLFPAEPTENRERTANEKTTSSPAE-------------PTENGQRTPFANEKTTSS 696
Query: 1946 PGERPSHSLSRDFKNQTTLL 1965
E H N+ T L
Sbjct: 697 SAEPTEHGERTPLANENTTL 716
Score = 87.8 bits (216), Expect = 9e-17
Identities = 111/517 (21%), Positives = 198/517 (38%), Gaps = 78/517 (15%)
Query: 1476 RTVQKDSSSRSKKNFYRNETSSQESKNLS------TPGTRVQARGRILPGSPVKRTWHRH 1529
RT ++++ ET++ E LS T + P P +
Sbjct: 447 RTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTP 506
Query: 1530 LKDKLTHKEHNHPSFYRERTPRG-------PSERTRHNPSWRNHRS------PSERSQRS 1576
++ T P+ + ERTP P+E T + N ++ P+E R+
Sbjct: 507 FANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRT 566
Query: 1577 SLERRHHSPS--------QRSHCSPSRKNHSS--PSERSWRSPSQRNHCSPPERSCHSLS 1626
L +PS QR+ + + SS P+E R+P + +P
Sbjct: 567 PLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENR 626
Query: 1627 ERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSH 1686
ER + + S GP++ R + +E++ P+E +E R R+ ++++ P+E
Sbjct: 627 ERTANENTTPSPAGPTENREMTANEKTTLFPAE-----PTENRERTANEKTTSSPAE--- 678
Query: 1687 CSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPS 1746
P+E R+P S P++ R+P +E + SP+E P+
Sbjct: 679 --PTENGQRTPFANEKTTSSSAE---PTEHGERTPLA------NENTTLSPAE-----PT 722
Query: 1747 ERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRR 1806
E R + +E++ P+E P+E R R+ +E SP++ P+E +P +
Sbjct: 723 ENRERTANEKTTPFPAE-----PTENRERTANENTTPSPAQ-----PTENGDRTPLANEK 772
Query: 1807 HSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSE 1866
+P S E R+P S +ER+ +E + SP E P+E
Sbjct: 773 TTP---SLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAE-----PTE 824
Query: 1867 RRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHC 1926
R +++ KT P+E P+ R+ +E++ E T + E + +
Sbjct: 825 NRERTANEKTTQFPAE-----PTENRESTANEKTTPFPAEPTEN--REWTANENTTLSPA 877
Query: 1927 SPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTT 1963
P+E +PL P E + F N+ T
Sbjct: 878 EPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKT 914
Score = 68.6 bits (166), Expect = 6e-11
Identities = 168/847 (19%), Positives = 318/847 (37%), Gaps = 143/847 (16%)
Query: 1192 SPISPSQRKAKIYTQASK----SPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTK 1247
SP P++ + + + PT + + +P+P + GQR+ P EKT
Sbjct: 456 SPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEP-TENGQRT-PFANEKTT 513
Query: 1248 TRAPG---HYEFTQVHNLPESDSESTQNEKRAKVRTKKTSDS---------KYPM--KRI 1293
+ + H E T + N + S + E R + +KT+ S + P+ ++
Sbjct: 514 SSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKT 573
Query: 1294 TKRLRK-----HRKFYTNSRTTIESPSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPK 1348
T L + R + N +TT S S E H R + A + +T S P +P++ +
Sbjct: 574 TPSLAEPTENGQRTPFANEKTT--SSSAEPTEHEERTPL-ANENTTPS----PAEPTENR 626
Query: 1349 FMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPS--SIK 1406
R + T P ++N N + P+ +
Sbjct: 627 -----------------------ERTANENTTPSPAGPTENREMTANEKTTLFPAEPTEN 663
Query: 1407 RDKRSADKLT--PAGSTIKQEDILWGGTVQCRSAQQP-----RRAYSFQPRPLRLPKPTD 1459
R++ + +K T PA T + + S+ +P R + + L +PT+
Sbjct: 664 RERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTE 723
Query: 1460 SQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQ-ARGRILP 1518
++ A + + P ++ R+ NE ++ + G R A + P
Sbjct: 724 NRERTANEKTT---PFPAEPTENRERTA-----NENTTPSPAQPTENGDRTPLANEKTTP 775
Query: 1519 G--SPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRS 1576
P + ++ T P+ + ERTP +E T +P+ P+E +R+
Sbjct: 776 SLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLA-NENTTSSPA-----EPTENRERT 829
Query: 1577 SLERRHHSPSQRSHCSPSRKNHSS------PSERSWRSPSQRNHCSPPERSCHS-----L 1625
+ E+ P++ + S N + P+E + ++ SP E + H
Sbjct: 830 ANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLA 889
Query: 1626 SERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERS 1685
+E+ SP++ + G + + S P+E R+ +PS+ P+E
Sbjct: 890 NEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAE---PTEHG 946
Query: 1686 HCSPSERRHRSPSQRSHRGPSERRHHS------PSKRSHRSPARRSHR--SPSERSHH-- 1735
+E+ SP++ + G + + P++ R+P + SP+E + H
Sbjct: 947 ERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTEHGE 1006
Query: 1736 -SPSERSHHSPSERRHH-----SPSER---SHCSPSERSHCSPSERRHRSPSERRHHSPS 1786
+ +E++ SP+E H S +E+ S P+E +PS + +PS +
Sbjct: 1007 RTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHG 1066
Query: 1787 EKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSH 1846
EK+ + +E+ SP H S + + S P+E ER+
Sbjct: 1067 EKTTLA-NEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEH-------------GERTT 1112
Query: 1847 SPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSER-SHRSPSGMRQGRTSERSHRSSC 1905
SP++K S E S R +S+ +P+E H + + + ++ + +S
Sbjct: 1113 SPNDKITSSAAE----STEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKS-- 1166
Query: 1906 ERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLL 1965
T H + R P+ S ++ +G P E+P+ +L TTL
Sbjct: 1167 --TEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVP-EKPTENL-----GNTTLT 1218
Query: 1966 GTTHKNP 1972
T K P
Sbjct: 1219 TETIKAP 1225
Score = 67.0 bits (162), Expect = 2e-10
Identities = 103/500 (20%), Positives = 184/500 (36%), Gaps = 104/500 (20%)
Query: 1550 PRGPSERTRHNPSWRNHRSPSERSQRSSLERR------------------HHSPSQRSHC 1591
P G S+ H S NH +P + SS + + H + + H
Sbjct: 99 PTGNSKTIDHKSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHI 158
Query: 1592 SPSRKN----HSSPSERSWRSPSQRNHCSPPERSCHSLSERGL--HSPSQRSHR-GPSQR 1644
+P+ K+ S + +S + P E+S +L + H + H G SQ
Sbjct: 159 TPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQT 218
Query: 1645 RHHSPS-------------------ERSHRSPSERSHRSSSERRHRS------------- 1672
+ S S E S ++ R+ +S + ++
Sbjct: 219 KQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANEL 278
Query: 1673 ------PSQRSHRGPSER---SHCSPSERRHRSPSQRSHRGPS---ERRHHSPSKRSHRS 1720
P++ R +E S P+E R R+ ++ + P+ E R + ++ +
Sbjct: 279 TQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPF 338
Query: 1721 PARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSER 1780
PA P+E + +E + P+E H ER+ + S P+E R+ +E
Sbjct: 339 PA-----GPTENREMTANENTTLFPAEPTEH--GERTANENTTPSPAEPTEHGERTANEN 391
Query: 1781 RHHSPSEKSHHS-----PSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFE 1835
SP+E + H ++++ S +E H + S P+E R + E
Sbjct: 392 TTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANE 451
Query: 1836 RSHRR----ISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGM 1891
+ R + +EK+ LSP+E P+E R +++ KT SP+E + +G
Sbjct: 452 NTTPSPAGPTENRETTANEKTTLSPVE-----PTENRETTANEKTTPSPAEPTE---NGQ 503
Query: 1892 RQGRTSERSHRSSCERTRH-----------SPSEMRPGRPSGRNHCSPSERSRRSPLKEG 1940
R +E++ SS E T H +PS P R + S P + G
Sbjct: 504 RTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENG 563
Query: 1941 LKYSFPGERPSHSLSRDFKN 1960
+ E+ + SL+ +N
Sbjct: 564 DRTPLANEKTTPSLAEPTEN 583
Score = 43.9 bits (102), Expect = 0.002
Identities = 69/353 (19%), Positives = 130/353 (36%), Gaps = 43/353 (12%)
Query: 1645 RHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRS----PSQR 1700
RH P+++ + H+SS++ P+ + S P R RS S
Sbjct: 91 RHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEEN---SSNQGKDPMIRNQRSVDPADSTT 147
Query: 1701 SHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCS 1760
+H+ + ++H +P+ +S + R+S S + S S S SH +
Sbjct: 148 THKESAGKKHITPAPKS-KINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKT 206
Query: 1761 PSERSHCSPSERRHRSPSERRHHSPSEKSHH------SPSERSHHSPSERRRHSPLERSR 1814
+ + S+ + +S S + + K+ + SE++ S + L ++
Sbjct: 207 TTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTT 266
Query: 1815 HSL--------LERSHRSPSERRSHRSFERSHRRISE----RSHSPSEKSHLSPLERSRC 1862
++ L +S P+E + E + +E R + +E + LSP E
Sbjct: 267 KNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAE---- 322
Query: 1863 SPSERRGHSSSGKTCHSPS------ERSHRSPSGMRQGRTSERSHRSSCERTRHSPSE-M 1915
P E R +++ T P+ E + + + +E R++ E T SP+E
Sbjct: 323 -PIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPT 381
Query: 1916 RPGRPSGRNHCSPS-----ERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTT 1963
G + + +PS E R+P S E H N+ T
Sbjct: 382 EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENT 434
>gi|171916097 repetin [Homo sapiens]
Length = 784
Score = 83.6 bits (205), Expect = 2e-15
Identities = 116/480 (24%), Positives = 184/480 (38%), Gaps = 100/480 (20%)
Query: 1533 KLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRS--- 1589
KL +K H + +ER G + + R HR E +++S HHS +R
Sbjct: 88 KLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQHRQRHEEERQNS----HHSQPERQDGD 143
Query: 1590 --HCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHH 1647
H P R++ S +S + +H S PER H+ S+R + S +
Sbjct: 144 SHHGQPERQDRDSHHGQSEKQDRDSHH-SQPERQ----DRDSHHNQSERQDKDFSFDQSE 198
Query: 1648 SPSERSHRSPSERSHRSSSER-----------RHRSPSQRSHRGPSER------------ 1684
S+ S S + SH+S+S + R P Q SH G SER
Sbjct: 199 RQSQDS-SSGKKVSHKSTSGQAKWQGHIFALNRCEKPIQDSHYGQSERHTQQSETLGQAS 257
Query: 1685 -----------SHCSPSERRHRS--------PSQRSHRGPSERRHHSPSKRSHRSPARRS 1725
S+C SER + Q SH G ++R+ S + S
Sbjct: 258 HFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSS 317
Query: 1726 HRSPSER----SHHSPSER----SHHSPSERR----HHSPSERSHCSPSERSHCSPSERR 1773
H S ++R SH+S +R SH+ +R+ H+ + R + SH S R+
Sbjct: 318 HYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQ----GQGSHYSQPNRQ 373
Query: 1774 HRSPSERRHHSPSEKSHHSPSER----SHHSPSERRRHSPLERSRHSLLER----SHRSP 1825
+S + + + SH+ ++R SH+ +ER+ S S +S ++R SH
Sbjct: 374 GQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQS----SHYSQMDRQGQGSHYGQ 429
Query: 1826 SERRSHRSFERSHRRISERSH-----SPSEKSHLSPLER----SRCSPSERRGHSSS-GK 1875
++R+ S R + SH + SH +R S S +++G SS GK
Sbjct: 430 TDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGK 489
Query: 1876 TCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRS 1935
+ P G Q SH +R S +P R +H S +R +S
Sbjct: 490 IDRQDQSYHYGQPDGQGQS-----SHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
Score = 69.3 bits (168), Expect = 3e-11
Identities = 87/414 (21%), Positives = 154/414 (37%), Gaps = 33/414 (7%)
Query: 1565 NHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHS 1624
+H S ++R +SS + Q SH + Q +H S P R S
Sbjct: 317 SHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQS 376
Query: 1625 LSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSER 1684
+ Q SH G + R+ S SH +ER +SS + Q SH G ++R
Sbjct: 377 SHYGQPDTQDQSSHYGQTDRQDQS----SHYGQTERQGQSSHYSQMDRQGQGSHYGQTDR 432
Query: 1685 SHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHS 1744
S + Q SH G ++R+ S SH R +S + SH+
Sbjct: 433 QGQSSHYGQPDRQGQNSHYGQTDRQGQS----SHYGQTDRQGQSSHYSQPDKQGQSSHYG 488
Query: 1745 PSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSER----SHHS 1800
+R+ S + SH ++R+ +S + + SH+S +R SH+
Sbjct: 489 KIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYG 548
Query: 1801 PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERS 1860
++R+ S S + +R +S ++ R + SH S+ + + E +
Sbjct: 549 QTDRQGQS----SHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGT 604
Query: 1861 RCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSP-------- 1912
R + + S + +P + +++ Q R S+++ E S
Sbjct: 605 RKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLA 664
Query: 1913 --SEMRPGRPSGRN--HCSPSERSRRSPLKEGLKYSFPGERPSHSLSRDFKNQT 1962
+ RP GR+ CS + R++ ++ GE SH + +QT
Sbjct: 665 QIQQERPLCHKGRDWQSCSSEQGHRQAQTRQS-----HGEGLSHWAEEEQGHQT 713
Score = 65.9 bits (159), Expect = 4e-10
Identities = 100/471 (21%), Positives = 169/471 (35%), Gaps = 79/471 (16%)
Query: 1557 TRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCS 1616
T W+ H R ++ ++ H+ S+R H S + ++C
Sbjct: 215 TSGQAKWQGHIFALNRCEKP-IQDSHYGQSER-HTQQSETLGQASHFNQTNQQKSGSYCG 272
Query: 1617 PPERSCHSLSERGLHSPSQRSHRGPSQRR----HHSPSER----SHRSPSERSHRSSSER 1668
ER L Q SH G + R+ H+ ++R SH S ++R +SS
Sbjct: 273 QSERLGQELGCGQTDRQGQSSHYGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYS 332
Query: 1669 RHRSPSQRSHRGPSER----------------SHCSPSERRHRS--------PSQRSHRG 1704
+ Q SH G +R SH S R+ +S Q SH G
Sbjct: 333 QPDRQGQSSHYGQMDRKGQCYHYDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYG 392
Query: 1705 PSERRHHSPSKRSHRSPARRSHRSPSER----SHHSPSERSHHSPSERRHHSPSERSHCS 1760
++R+ S + SH S +R SH+ ++R S + + SH
Sbjct: 393 QTDRQDQSSHYGQTERQGQSSHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYG 452
Query: 1761 PSER----SHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHS 1816
++R SH ++R+ +S + + SH+ +R S + + S +
Sbjct: 453 QTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYG 512
Query: 1817 LLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLER----SRCSPSERRGHSS 1872
+R +S + R + SH +R + SH +R S ++R+G S
Sbjct: 513 QTDRQGQSFHYGQPDRQGQSSHYSQMDRQ---GQSSHYGQTDRQGQSSHYGQTDRQGQSY 569
Query: 1873 SGKTCHSPSERSH--RSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSE 1930
+ SH +S +G QG + + E TR + + GR SGR
Sbjct: 570 HYGQTDRQGQSSHYIQSQTGEIQG---QNKYFQGTEGTRKASYVEQSGR-SGR------- 618
Query: 1931 RSRRSPLKEGLKYSFPGERPSHSLSRDFKNQTTLLGTTHKNPKAGQVWRPE 1981
S+++P +EG ++NQ + QVW PE
Sbjct: 619 LSQQTPGQEG-----------------YQNQGQGFQSRDSQQNGHQVWEPE 652
Score = 60.8 bits (146), Expect = 1e-08
Identities = 81/405 (20%), Positives = 143/405 (35%), Gaps = 51/405 (12%)
Query: 1565 NHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHS 1624
+H S R +SS + + Q SH + + S Q +H S +R
Sbjct: 365 SHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSSHYGQTERQGQSSHYSQMDRQGQG 424
Query: 1625 LSERGLHSPSQRSHRGPSQRR----HHSPSER----SHRSPSERSHRSSSERRHRSPSQR 1676
Q SH G R+ H+ ++R SH ++R +SS + Q
Sbjct: 425 SHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQS 484
Query: 1677 SHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER---- 1732
SH G +R S + Q SH G ++R+ S + SH S +R
Sbjct: 485 SHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQS 544
Query: 1733 SHHSPSER----SHHSPSERR----HHSPSER----SHCSPSERSHCSPSERRHRSPSER 1780
SH+ ++R SH+ ++R+ H+ ++R SH S+ + +
Sbjct: 545 SHYGQTDRQGQSSHYGQTDRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGT 604
Query: 1781 RHHSPSEKSHHS-------PSERSHHSPSERRRHSPLERSRHSLLE-------RSHRSPS 1826
R S E+S S P + + + + + +++ H + E H+ +
Sbjct: 605 RKASYVEQSGRSGRLSQQTPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLA 664
Query: 1827 ERRSHR------------SFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSG 1874
+ + R S E+ HR+ R SH + E+ +R H S
Sbjct: 665 QIQQERPLCHKGRDWQSCSSEQGHRQAQTRQSHGEGLSHWAEEEQGH-QTWDRHSHESQE 723
Query: 1875 KTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGR 1919
C + R+H+ ++ H S +R E + R
Sbjct: 724 GPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRRDRQTHEDKQNR 768
Score = 43.5 bits (101), Expect = 0.002
Identities = 74/345 (21%), Positives = 119/345 (34%), Gaps = 78/345 (22%)
Query: 1565 NHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHS 1624
+H ++R +SS + Q SH S K S Q H P+ S
Sbjct: 449 SHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQS 508
Query: 1625 LSERGLHSPSQRSHRGPSQRR----HHSPSER----SHRSPSERSHRSSSERRHRSPSQR 1676
Q H G R+ H+S +R SH ++R +SS + Q
Sbjct: 509 SHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQTDRQGQS 568
Query: 1677 SHRGPSER----SHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSER 1732
H G ++R SH S+ + +G R S ++S RS R S ++P +
Sbjct: 569 YHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRS-GRLSQQTPGQE 627
Query: 1733 SHHS-------------------PSERSHHSP------------------------SERR 1749
+ + P E S H SE+
Sbjct: 628 GYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQERPLCHKGRDWQSCSSEQG 687
Query: 1750 HHSPSER-------SHCSPSERSHCSPSERRHRSPS------ERRHHSPSEKSHHSPSER 1796
H R SH + E+ H + H S +RR H E++H +
Sbjct: 688 HRQAQTRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHK-DEQNHQRRDRQ 746
Query: 1797 SH-HSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRR 1840
+H H S +RR +R H ++ +R +R++H E++H+R
Sbjct: 747 THEHEQSHQRR----DRQTHE--DKQNRQRRDRQTHED-EQNHQR 784
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 83.2 bits (204), Expect = 2e-15
Identities = 151/551 (27%), Positives = 203/551 (36%), Gaps = 118/551 (21%)
Query: 1442 RRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESK 1501
RR+ S+ P P++ K S+ K S SKK R+ +SS +SK
Sbjct: 121 RRSSSYSPSPVKKKKKKSSKK----------------HKRRRSFSKKR--RHSSSSPKSK 162
Query: 1502 NLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNP 1561
+ Q+R R P K HRH H PS + R S +RH
Sbjct: 163 RRDEKRHKKQSRSR-----PRKSHRHRH---------HRCPSRSQSSESRPSSCESRHRG 208
Query: 1562 SWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERS 1621
RSP E Q+S RRH ++ C SP +S R PSQ P +
Sbjct: 209 -----RSPEE-GQKS--RRRHSRRCSKTLCK------DSPEAQSSRPPSQ------PLQM 248
Query: 1622 CHSLSERGLHSPSQRS-------------HRGPSQRRHHSPSERSHRSPSERSHRSSSER 1668
LS RG+ + S + RG SQ + S ++ S ++ S S +
Sbjct: 249 LGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQE-YDSGNDTSSPPSTQTSSARSRGQ 307
Query: 1669 RHRSPS---QRSHRGPSERSHCSPSERRHRSPSQR---------SHRGPSERRHHSPS-- 1714
SPS +S S + S + SP + + RG R SP
Sbjct: 308 EKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLE 367
Query: 1715 ----KRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPS-ERSHCSP 1769
K+S P+ + SP + S S S S S H S S SP +S +
Sbjct: 368 CAEVKKSSLVPST-ARSSPMKGCSRSSSYASTRSSS---HSSRSPNPRASPRYTQSRSTS 423
Query: 1770 SERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERR 1829
SE+R S S ++S S S RS SPS R+SP ER + +
Sbjct: 424 SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPS-YSRYSPSR-------ERDPKYSEKDS 475
Query: 1830 SHRSFERSHRRISERSHSPSEK------SHLS----------PLERSRCSPSERRGHSSS 1873
R ER+ RR RS+SP K SHL P+ R SPS SS+
Sbjct: 476 QQRERERARRR--RRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSST 533
Query: 1874 GKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSR 1933
S S RS + + R+ RS R S RT S S P P R+ RSR
Sbjct: 534 SSWYSSSSSRS--ASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPS-PGSRSRSRSRSRSR 590
Query: 1934 RSPLKEGLKYS 1944
+ YS
Sbjct: 591 SRSRSQSRSYS 601
Score = 77.0 bits (188), Expect = 2e-13
Identities = 137/534 (25%), Positives = 206/534 (38%), Gaps = 89/534 (16%)
Query: 1402 PSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPK----- 1456
PS +K+ K+ + K + ++ + + + + R + RP + +
Sbjct: 128 PSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR 187
Query: 1457 -PTDSQSGIAFQTASVGQPL-RTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARG 1514
P+ SQS + ++ + R+ ++ SR + + ++T ++S +A+
Sbjct: 188 CPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSP---------EAQS 238
Query: 1515 RILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE-RTRHNPSWRNHRSPSERS 1573
P P++ + + +T F + +P S R++ S + SP
Sbjct: 239 SRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQ 298
Query: 1574 QRSSLERRHHSPSQRSHCSPSRKNHS---SPSERSWRSPSQRN------HCSPPERSCHS 1624
S+ R S S SR+ +S S S S+ + S +N + SP R S
Sbjct: 299 TSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRES 358
Query: 1625 LSERGLHSPS------QRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSH 1678
RG SP ++S PS R SP + RS S S RSSS S
Sbjct: 359 ---RGFQSPCLECAEVKKSSLVPSTARS-SPMKGCSRSSSYASTRSSSH---------SS 405
Query: 1679 RGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPS 1738
R P+ R+ SP + RS S SE+R +S S +RS S S RS SPS
Sbjct: 406 RSPNPRA--SPRYTQSRSTS-------SEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPS 456
Query: 1739 ERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHH-SPSE-R 1796
S +SPS R SE+ S R R+ RR +SP K SPS
Sbjct: 457 Y-SRYSPSRERDPKYSEKD----------SQQRERERARRRRRSYSPMRKRRRDSPSHLE 505
Query: 1797 SHHSPSERRRHSPLER----SRHSLLERS--HRSPSERRSHRSFERSHRRISERSHSPSE 1850
+ S R+R P R S SL S + S S R + RS+ RS R R S
Sbjct: 506 ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRS--- 562
Query: 1851 KSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSS 1904
R+R S S S G S S RS S R+ RS+ S+
Sbjct: 563 --------RTRTSSSSSSRSPSPGSRSRSRSRSRSRSRS-----RSQSRSYSSA 603
Score = 76.6 bits (187), Expect = 2e-13
Identities = 143/583 (24%), Positives = 222/583 (38%), Gaps = 89/583 (15%)
Query: 1263 PESDSESTQNEKRAKVRTKKTSDSKYPMKR----ITKRLRKHRKFYTNSRTTIESPSREL 1318
P S + + + K R + +S S P+K+ +K+ ++ R F R + SP +
Sbjct: 104 PSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKR 163
Query: 1319 AAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDG 1378
R K+ ++ + R + PS+ + +S + ++ HR GR P +G
Sbjct: 164 RDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSS----ESRPSSCESRHR-----GRSPEEG 214
Query: 1379 TRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSA 1438
+ S+ + ++ ++ C S + R + + ++ G
Sbjct: 215 QK------SRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITG-------- 260
Query: 1439 QQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQ 1498
+ S + + +TAS PL T S RS++ N+TSS
Sbjct: 261 -------------------SGSAADLFTKTAS---PLTT----SRGRSQEYDSGNDTSSP 294
Query: 1499 ESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTR 1558
S S+ +R Q +G P + ++ R L T N SF T P +
Sbjct: 295 PSTQTSSARSRGQEKGS--PSGGLSKS--RELNSGNTSDSGN--SF----TTSSP----Q 340
Query: 1559 HNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPP 1618
+ + + SP+ R + S R SP C+ +K+ PS + RS +
Sbjct: 341 NKGAMLENLSPTSRGRES---RGFQSPC--LECAEVKKSSLVPS--TARSSPMKGCSRSS 393
Query: 1619 ERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSH-RSPSERSHRSSSERRHRSPSQRS 1677
+ S SP+ R+ +Q R S +RS+ RSPS S S +R S S RS
Sbjct: 394 SYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSS--KSGKRSPPSRSSRS 451
Query: 1678 HRGPSERSHCSPSERRHRSPSQRS------HRGPSERRHHSPSKRSHR-SPAR-RSHRSP 1729
R PS S SPS R S++ R RR +SP ++ R SP+ + R
Sbjct: 452 RRSPS-YSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRIT 510
Query: 1730 SERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKS 1789
S R P R SPS S + + S S RS S S R RS S R S + S
Sbjct: 511 SARKRPIPYYRP--SPSSSGSLSSTSSWYSSSSSRS-ASRSYSRSRSRSRSRRRSRTRTS 567
Query: 1790 HHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHR 1832
S S R R RSR RS+ S S R
Sbjct: 568 SSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTR 610
Score = 70.5 bits (171), Expect = 2e-11
Identities = 122/467 (26%), Positives = 173/467 (37%), Gaps = 65/467 (13%)
Query: 1543 SFYRERTPRGPSERTRHNPSWRNHRSP------SERSQRSSLERRHHSPSQRSHCSPSRK 1596
S+ R++T R H+ S +P ++ ++S+ ++R S S +K
Sbjct: 76 SWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKK 135
Query: 1597 NHSSPSERSWRSPSQ-RNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHR 1655
SS + RS S+ R H S +S +R R + R H PS R
Sbjct: 136 KKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPS----R 191
Query: 1656 SPSERSHRSSSERRH--RSP-----SQRSHRGPSERSHC--SPSERRHRSPSQ------- 1699
S S S SS E RH RSP S+R H ++ C SP + R PSQ
Sbjct: 192 SQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGY 251
Query: 1700 RSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHC 1759
S RG + + + + R RS S SP + S R
Sbjct: 252 LSARGVITGSGSAADLFTKTASPLTTSRG---RSQEYDSGNDTSSPPSTQTSSARSRGQE 308
Query: 1760 SPSERSHCSPS-ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSP--------- 1809
S S S E + S+ + + + + + SP+ R R S
Sbjct: 309 KGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRGFQSPCLEC 368
Query: 1810 LERSRHSLLERSHR-SPSERRSHRSFERSHRRISERSHSPSEKSHLSP-LERSRCSPSER 1867
E + SL+ + R SP + S S S R S S SP+ ++ SP +SR + SE+
Sbjct: 369 AEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRA--SPRYTQSRSTSSEK 426
Query: 1868 RGHS--------SSGKTCHSPSERSHRSPSGMRQGRTSERS-----------HRSSCERT 1908
R +S S ++ S S RS RSPS R + ER R R
Sbjct: 427 RSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRR 486
Query: 1909 RHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLS 1955
R S S MR R +H R S K + Y P S SLS
Sbjct: 487 RRSYSPMRKRRRDSPSHL--EARRITSARKRPIPYYRPSPSSSGSLS 531
Score = 47.4 bits (111), Expect = 1e-04
Identities = 53/201 (26%), Positives = 72/201 (35%), Gaps = 24/201 (11%)
Query: 1713 PSKRSHRSPARRSHRSPSER-SHHSPSERSHHSPSER----------RHHSPSERSHCSP 1761
P +P + PSE+ H +E + ER R HS S +P
Sbjct: 43 PRTEPQNNPVVPAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTP 102
Query: 1762 SERSHCSPSERRHRSPSERRH--HSPS----EKSHHSPSERSHHSPSERRRHSPLERSRH 1815
S +++ RR +SPS +K S + S S++RRHS
Sbjct: 103 PPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSK 162
Query: 1816 SLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSE----RRGHS 1871
E+ H+ S R +S H R RS S + SP E RR HS
Sbjct: 163 RRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHS 222
Query: 1872 --SSGKTC-HSPSERSHRSPS 1889
S C SP +S R PS
Sbjct: 223 RRCSKTLCKDSPEAQSSRPPS 243
Score = 35.0 bits (79), Expect = 0.73
Identities = 29/140 (20%), Positives = 62/140 (44%), Gaps = 2/140 (1%)
Query: 1189 IRRSPISPSQRKAKIYTQASKSPT-STIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTK 1247
+++S + PS ++ S+S + ++ S S+SP P + R Q +++
Sbjct: 371 VKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNP-RASPRYTQSRSTSSEKRSY 429
Query: 1248 TRAPGHYEFTQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNS 1307
+R+P + + + P S S ++ ++ + D KY K +R R+ + S
Sbjct: 430 SRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS 489
Query: 1308 RTTIESPSRELAAHLRRKRI 1327
+ + R+ +HL +RI
Sbjct: 490 YSPMRKRRRDSPSHLEARRI 509
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 82.8 bits (203), Expect = 3e-15
Identities = 98/333 (29%), Positives = 127/333 (38%), Gaps = 30/333 (9%)
Query: 1554 SERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC-SPSRKNHSSPSERSWRSPSQR 1612
S R R R+H RS+ S R S+ SH S SR S S RS SQ
Sbjct: 179 SRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQS 238
Query: 1613 NHCSPPERSCHSLSERGL---HSPSQRSHRGPSQRRHHSPSERSHRSPSERS---HRSSS 1666
S E+S E+ HS + + Q + + P RS H+S S
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298
Query: 1667 ERRHRSPSQR---SHRGPSERSHC---SPSERRHRSPSQRSHRGPSERRHHSPSKRSHRS 1720
+ R RS +R RG R S + R RS S+ R S R S KR R
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK 358
Query: 1721 PARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSER 1780
+R RS S S SERS S+R + S + E + S S RS S+
Sbjct: 359 RSREESRSRSRS--RSKSERSRKRGSKRDSKAGSSKK--KKKEDTDRSQSRSPSRSVSKE 414
Query: 1781 RHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRR 1840
R H+ SE S S ++ + + S RSR S P+ RS +S +
Sbjct: 415 REHAKSESSQREGRGESENAGTNQETRS---RSR----SNSKSKPNLPSESRSRSKSASK 467
Query: 1841 ISERSHSPSEKSHLSPLERSRCSPSERRGHSSS 1873
RS S S + SP S S R HS S
Sbjct: 468 TRSRSKSRSRSASRSP------SRSRSRSHSRS 494
Score = 82.4 bits (202), Expect = 4e-15
Identities = 92/331 (27%), Positives = 131/331 (39%), Gaps = 22/331 (6%)
Query: 1601 PSERSWRSPSQ-RNHCSPPERSCHSLSERGLHSPSQRSH-RGPSQRRHHSPSERSHRSPS 1658
P R RS S+ R+H RS HS R S+ SH + S+ R S S RS S
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 1659 ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRS- 1717
+ RS E+ RSPS+ R RSH S + R +S Q + + P RS
Sbjct: 237 QSRSRSKKEKS-RSPSKEKSRS---RSH-SAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
Query: 1718 --HRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHR 1775
H+S ++ RS R E S S R S R S S S S R R
Sbjct: 292 SRHKSKSKSRSRSQERRVE----EEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR 347
Query: 1776 SPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLER-SRHSLLERSHRSPSERRSHRSF 1834
S S+ + S S S SER R +R S+ ++ + ++R RS
Sbjct: 348 SKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSP 407
Query: 1835 ERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQG 1894
RS + ER H+ SE S +R SE G + ++ + +S + +
Sbjct: 408 SRSVSK--EREHAKSESS-----QREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRS 460
Query: 1895 RTSERSHRSSCERTRHSPSEMRPGRPSGRNH 1925
R+ S S ++R + P R R+H
Sbjct: 461 RSKSASKTRSRSKSRSRSASRSPSRSRSRSH 491
Score = 82.0 bits (201), Expect = 5e-15
Identities = 100/342 (29%), Positives = 142/342 (41%), Gaps = 31/342 (9%)
Query: 1617 PPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQR 1676
P R S S HS S+ R + R S S +S S S RS S R +S S+
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 1677 SHRGPSERSHC-SPSERRHRSPSQRSHRGPSERRHHSPSK-RSHRSPARRSHRSPSERSH 1734
R S++ SPS+ + RS S + + S+ + + K +++ + + RSPS
Sbjct: 237 QSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSR--- 293
Query: 1735 HSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPS 1794
H S S+ R S R E S S R + S R+ S S S S
Sbjct: 294 -------HKSKSKSRSRSQERR----VEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 1795 ERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHL 1854
S S+ +R +RSR E RS S +S RS +R +R S+ S +K
Sbjct: 343 RSRSRSKSKDKRKG-RKRSRE---ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398
Query: 1855 SPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSE 1914
+ +SR SPS S S + H+ SE S R G + + + RS R+R S S+
Sbjct: 399 TDRSQSR-SPS----RSVSKEREHAKSESSQREGRGESENAGTNQETRS---RSR-SNSK 449
Query: 1915 MRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSR 1956
+P PS S S RS K + + PS S SR
Sbjct: 450 SKPNLPSESRSRSKSASKTRSRSKSRSRSA--SRSPSRSRSR 489
Score = 75.1 bits (183), Expect = 6e-13
Identities = 92/345 (26%), Positives = 129/345 (37%), Gaps = 26/345 (7%)
Query: 1507 GTRVQARGRIL----PGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE----RTR 1558
GT V R L PGS +R++ R + H R R+ S R+R
Sbjct: 162 GTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSR 221
Query: 1559 HNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSR-----KNHSSPSERSWRSPSQRN 1613
R+ RSQ S ++ S S S SR K+ S +++ +
Sbjct: 222 SRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNND 281
Query: 1614 HCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSP 1673
+ P+ S + S S+ R + + S S + S R RS S + S
Sbjct: 282 NVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSR 341
Query: 1674 SQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERS 1733
S+ R S+ R S S+ R SER SKR S A S + E +
Sbjct: 342 SRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRD--SKAGSSKKKKKEDT 399
Query: 1734 HHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSP 1793
S S S S+ R H+ SE S S + + + RS R S S+ + P
Sbjct: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRS----RSRSNSKSKPNLP 455
Query: 1794 SE-RSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERS 1837
SE RS + + R RSR + RSPS RS RS RS
Sbjct: 456 SESRSRSKSASKTRSRSKSRSR-----SASRSPSRSRS-RSHSRS 494
Score = 59.3 bits (142), Expect = 4e-08
Identities = 74/227 (32%), Positives = 87/227 (38%), Gaps = 34/227 (14%)
Query: 1769 PSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSER 1828
P RR RS S R HS S RS HS R R S +S HS RS S
Sbjct: 177 PGSRRRRSYSRSRSHSRSRS-------RSRHSRKSRSR-SGSSKSSHSKSRSRSRSGSRS 228
Query: 1829 RSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSS--------------- 1873
RS +S R RS S EKS E+SR S S G S S
Sbjct: 229 RS-----KSRSRSQSRSRSKKEKSRSPSKEKSR-SRSHSAGKSRSKSKDQAEEKIQNNDN 282
Query: 1874 -GK-TCHSPSERSHRSPSGMR-QGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSE 1930
GK SPS +S S R Q R E R S R R +R R R+
Sbjct: 283 VGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRS 342
Query: 1931 RSR-RSPLKEGLKYSFPGERPSHSLSRD-FKNQTTLLGTTHKNPKAG 1975
RSR RS K+ K S S SR K++ + + ++ KAG
Sbjct: 343 RSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAG 389
Score = 42.4 bits (98), Expect = 0.005
Identities = 85/389 (21%), Positives = 143/389 (36%), Gaps = 78/389 (20%)
Query: 1299 KHRKFYTNSRTTIESPSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLK 1358
+ R+ Y+ SR+ S SR + R R G++++S + + + + S+ + +S
Sbjct: 180 RRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRS-----KSRS 234
Query: 1359 RAFQTAHRVIASVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPA 1418
R+ Q+ R R P SK K +R + S + K A++
Sbjct: 235 RS-QSRSRSKKEKSRSP-----------SKE---KSRSRSHSAGKSRSKSKDQAEEKIQN 279
Query: 1419 GSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTV 1478
+ G + RS + + + R + + + G + S + LR
Sbjct: 280 NDNV--------GKPKSRSPSRHKSKSKSRSRSQER-RVEEEKRGSVSRGRSQEKSLR-- 328
Query: 1479 QKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKE 1538
Q S SRSK G+R ++R R KDK ++
Sbjct: 329 QSRSRSRSK------------------GGSRSRSRSR------------SKSKDKRKGRK 358
Query: 1539 HNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKN- 1597
+ R SER+R S R+ ++ S + ++ R S S S R++
Sbjct: 359 RSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHA 418
Query: 1598 HSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSP 1657
S S+R R S+ G + ++ R S+ + + PSE RS
Sbjct: 419 KSESSQREGRGESE---------------NAGTNQETRSRSRSNSKSKPNLPSESRSRSK 463
Query: 1658 SERSHRSSSERRHRSPSQRSHRGPSERSH 1686
S RS S+ R RS S+ R S RSH
Sbjct: 464 SASKTRSRSKSRSRSASRSPSRSRS-RSH 491
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 82.4 bits (202), Expect = 4e-15
Identities = 95/383 (24%), Positives = 132/383 (34%), Gaps = 37/383 (9%)
Query: 1489 NFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHL--------KDKLTHKEHN 1540
+++ + +E ++ G V G +L K W L + + +
Sbjct: 176 DWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKT 235
Query: 1541 HPSFYRERTPRGPSERTRHNPSWRNHRSPSE-----RSQRSSLERRHHSPSQRSHCSPSR 1595
P ++ G E RH R RSP RS R S R HH S
Sbjct: 236 RPRKIKKDGKEGAEEIDRHVER-RRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRE 294
Query: 1596 KNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHR 1655
+R R +R ER +RGL R S+ RH S S R
Sbjct: 295 LEREKERQRLEREAKEREK----ERRRSRSIDRGLER-----RRSRSRERHRSRSRSRDR 345
Query: 1656 SPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSER---RHRSPSQRSHRGPSERRHHS 1712
R E+ + +R ER + ER R RS QRS RG E + H
Sbjct: 346 KGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRS-RGEVEEKKHK 404
Query: 1713 PSK--RSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770
K R HR R S + + S ER H S S R + +RS E+S +
Sbjct: 405 EDKDDRRHRDDKRDSKKE-KKHSRSRSRERKHRSRS--RSRNAGKRSRSRSKEKSSKHKN 461
Query: 1771 ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRS 1830
E + +S R S S++ HSPS+ + R R ERSH+
Sbjct: 462 ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEK-----SRKRSRSKERSHKRDHSDSK 516
Query: 1831 HRSFERSHRRISERSHSPSEKSH 1853
+S + RR EK H
Sbjct: 517 DQSDKHDRRRSQSIEQESQEKQH 539
Score = 77.4 bits (189), Expect = 1e-13
Identities = 79/301 (26%), Positives = 111/301 (36%), Gaps = 24/301 (7%)
Query: 1645 RHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRG 1704
R S S R SP RS S HR H S + R R + R
Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHRE----GHGSSSFDRELEREKERQRLEREAKERE 312
Query: 1705 PSERRHHSPSK--RSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPS 1762
RR S + RS +R HRS S R E+ + R
Sbjct: 313 KERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDK 372
Query: 1763 ERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSH 1822
ER + R + R S ++S E+ H + RRH + R S E+ H
Sbjct: 373 ERGN-----EREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHR--DDKRDSKKEKKH 425
Query: 1823 -RSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKT-CHSP 1880
RS S R HRS RS R +RS S S++ S+ ++R S G+T
Sbjct: 426 SRSRSRERKHRSRSRS-RNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEK 484
Query: 1881 SERSHRSPS---GMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPL 1937
S++ SPS ++ R+ ERSH+ HS S+ + + R S + S+
Sbjct: 485 SKKREHSPSKEKSRKRSRSKERSHKRD-----HSDSKDQSDKHDRRRSQSIEQESQEKQH 539
Query: 1938 K 1938
K
Sbjct: 540 K 540
Score = 71.2 bits (173), Expect = 9e-12
Identities = 75/305 (24%), Positives = 112/305 (36%), Gaps = 39/305 (12%)
Query: 1528 RHLKDKLTHKE-HNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPS 1586
R + + H+E H SF RE +R R RS LERR
Sbjct: 274 RRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRR---- 329
Query: 1587 QRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQR-- 1644
S SR+ H S S R +R+ E+ R +R + +R
Sbjct: 330 -----SRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERER 384
Query: 1645 -RHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHR 1703
R S +RS E+ H+ + R +R + + S ER+HRS S+ +
Sbjct: 385 SRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNA 444
Query: 1704 GPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHH-SPSERRHHSPSERSHCSPS 1762
G +R S SK S ++RS R+ S++R HSPS+
Sbjct: 445 G---KRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSK------- 494
Query: 1763 ERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSH 1822
+ R RS S+ R H K HS S + +RRR +E+ E+ H
Sbjct: 495 -------EKSRKRSRSKERSH----KRDHSDS-KDQSDKHDRRRSQSIEQESQ---EKQH 539
Query: 1823 RSPSE 1827
++ E
Sbjct: 540 KNKDE 544
Score = 68.2 bits (165), Expect = 8e-11
Identities = 82/318 (25%), Positives = 116/318 (36%), Gaps = 19/318 (5%)
Query: 1651 ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRH 1710
++ + +E R RR RSP R S R SP R RS + H S R
Sbjct: 241 KKDGKEGAEEIDRHVERRRSRSP----RRSLSPRR--SPRRSRSRSHHREGHGSSSFDRE 294
Query: 1711 HSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770
K +R R ER RS ERR ER H S S RS
Sbjct: 295 LEREKER-----QRLEREAKEREKERRRSRSIDRGLERRRSRSRER-HRSRS-RSRDRKG 347
Query: 1771 ERRHRSPS-ERRHHSPSEKSHHSPSERSHHSPSERRR---HSPLERSRHSLLERSHRSPS 1826
+RR R E+ + + ER + ER R S +RSR + E+ H+
Sbjct: 348 DRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407
Query: 1827 ERRSHRSFERSHRRISERSHSPS-EKSHLS-PLERSRCSPSERRGHSSSGKTCHSPSERS 1884
+ R HR +R ++ + S S S E+ H S R+ S R S K + E+S
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKS 467
Query: 1885 HRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS 1944
++ QGRT E + + R R+H S+ K + S
Sbjct: 468 NKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRS 527
Query: 1945 FPGERPSHSLSRDFKNQT 1962
E+ S K++T
Sbjct: 528 QSIEQESQEKQHKNKDET 545
Score = 64.3 bits (155), Expect = 1e-09
Identities = 81/305 (26%), Positives = 109/305 (35%), Gaps = 32/305 (10%)
Query: 1681 PSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPAR-----RSHRSPSERSHH 1735
P +++ + R R + G E H +RS RSP R RS R RSHH
Sbjct: 224 PVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRS-RSPRRSLSPRRSPRRSRSRSHH 282
Query: 1736 SPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSER---RHHSPSEKSHHS 1792
S E +R ER ERR +R R S S + H S
Sbjct: 283 REGHGSSSFDRELEREKERQRLEREAKERE----KERRRSRSIDRGLERRRSRSRERHRS 338
Query: 1793 PSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKS 1852
S RS +RR +R R ER R + R ER R R S ++S
Sbjct: 339 RS-RSRDRKGDRRDR---DREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRS 394
Query: 1853 HLSPLERSRCSPSERRGH-----SSSGKTCHSPS---ERSHRSPSGMR------QGRTSE 1898
E+ + R H S + HS S ER HRS S R + R+ E
Sbjct: 395 RGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKE 454
Query: 1899 RSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSLSR-D 1957
+S + E S R G + S++ SP KE + + SH D
Sbjct: 455 KSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSD 514
Query: 1958 FKNQT 1962
K+Q+
Sbjct: 515 SKDQS 519
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 80.1 bits (196), Expect = 2e-14
Identities = 165/797 (20%), Positives = 265/797 (33%), Gaps = 57/797 (7%)
Query: 1190 RRSPISPSQRKAKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTR 1249
RRSP P+ + + + T + +S +PV+ RG+ + ++ TK R
Sbjct: 75 RRSPERPTG-DLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKER 133
Query: 1250 APGHYEFTQVHNLPESDSESTQNE----KRAKVRTKKTSDSKYPMKRITKRLRKHRKFYT 1305
P E DS++ + K+ + MK + + K +
Sbjct: 134 TPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIII 193
Query: 1306 NSRTTIE------SPSRELAAHLRR-KRIGATQTSTASLK-RQPKKPSQPKFMQLLFQSL 1357
+ E SPS L + KR + ++S+AS K R+ S P Q
Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKT 253
Query: 1358 KRAFQTAHRVIA---------SVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRD 1408
++ + R + ++G+K + + + K K RD+ +R+
Sbjct: 254 NQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDF----ERQRE 309
Query: 1409 KRSADKLT--------PAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTDS 1460
KR + T P S G ++Q R + PRR + P R P
Sbjct: 310 KRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQ-RHSPSPRRKRTPSPSYQRTLTPPLR 368
Query: 1461 QSGIAFQTASVGQPLR--TVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILP 1518
+S + + S+ P R + + S +K + +E +SQ + +
Sbjct: 369 RSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREK 428
Query: 1519 GSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSE------- 1571
S +R + + H++ P R+R + R R+ R E
Sbjct: 429 DSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRD 488
Query: 1572 ----RSQRSSLERRH-HSPSQRSHCSPSRKNHSSPSE-RSWRSPSQRNHCSPPERSCHSL 1625
R R S R H R RK + P E RS+ R S E S
Sbjct: 489 TKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRNESR 548
Query: 1626 SERGLHSPSQRSHRGPSQRRHHSPSERSHRSP--SERSHRSSSERRHRSPSQRSHRGPSE 1683
+E S + G S+ R E+ R S+ SS+ H S RS +
Sbjct: 549 NES--RSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERD 606
Query: 1684 RSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHH 1743
R + + R S G +RR + + SP R R+ ER
Sbjct: 607 RYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVD 666
Query: 1744 SPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSE 1803
+RR ER +R ER E+ E++ ER E
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 1804 RRRHSPLERSRHSLLERSHRSPSER-RSHRSFERSHRRISERSHS-PSEKSHLSPLERSR 1861
R R +R R ER ER R R ER R ER E++ ER R
Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERER 786
Query: 1862 CSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRS-SCERTRHSPSEMRPGRP 1920
E + + R R+P R S++ +R+ R SP R P
Sbjct: 787 QRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSP 846
Query: 1921 SGRNHCSPSERSRRSPL 1937
+ S +++ + L
Sbjct: 847 DSDAYNSGDDKNEKHRL 863
Score = 66.6 bits (161), Expect = 2e-10
Identities = 115/471 (24%), Positives = 157/471 (33%), Gaps = 71/471 (15%)
Query: 1508 TRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHR 1567
T Q R SPV++ R H+E +ERTP E N W +R
Sbjct: 98 TEPQKRNTEESSSPVRKESSRG-----RHREKEDIKITKERTPESEEE----NVEWETNR 148
Query: 1568 SPSERSQRS-------SLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPER 1620
S+ + SLE + QR ++N E + PE
Sbjct: 149 DDSDNGDINYDYVHELSLEMKRQK-IQRELMKLEQENMEKREEIIIKKEVS------PEV 201
Query: 1621 SCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSS----ERRHRSPSQR 1676
LS SPS R S +R SP S ++ SS ++R+ +Q
Sbjct: 202 VRSKLSP----SPSLRKS-SKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQS 256
Query: 1677 SHRGPSERSHCSP-----------------SERRHRSPSQRSHRGPS-ERRHHSPSKRSH 1718
+GP S P +R RG ER+ K
Sbjct: 257 KKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRS 316
Query: 1719 RSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPS 1778
SPA + H SP HHS S +S S + HSPS R +PS PS +R +P
Sbjct: 317 TSPAGQ-HHSPISSRHHSSSSQSG---SSIQRHSPSPRRKRTPS------PSYQRTLTPP 366
Query: 1779 ERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSH 1838
RR SP S +R P R R H +SH ERR +R
Sbjct: 367 LRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDR 426
Query: 1839 RRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSE 1898
+ S + S R P + R + T R R R+ R
Sbjct: 427 EKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYS 486
Query: 1899 RSHRSSCE-------RTRHSPSEMRPGRPSGRNHCSPSERSR---RSPLKE 1939
R + S + R H + R GR + R + E SR R+ L+E
Sbjct: 487 RDTKESRDPRDSRSTRDAHDYRD-REGRDTHRKEDTYPEESRSYGRNHLRE 536
Score = 65.1 bits (157), Expect = 7e-10
Identities = 151/762 (19%), Positives = 237/762 (31%), Gaps = 95/762 (12%)
Query: 1236 QRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITK 1295
QR + D T H + H+ S S S+ R K+T Y + +T
Sbjct: 307 QREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSY-QRTLTP 365
Query: 1296 RLRKHRKFYTN----SRTTIESPSRELAAHLRRKRIGATQTSTASL-----------KRQ 1340
LR+ Y + S +SP R + + R +TS + KR
Sbjct: 366 PLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRD 425
Query: 1341 PKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRPDN-LWASKNYYPKQNARDY 1399
+K S+ + QS R + R+ TR L S++ + RDY
Sbjct: 426 REKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDY 485
Query: 1400 CLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQPRRAYSFQPRPLRLPKPTD 1459
+ RD R + A +E G + P + S+ LR +
Sbjct: 486 SRDTKESRDPRDSRSTRDAHDYRDRE----GRDTHRKEDTYPEESRSYGRNHLR-----E 536
Query: 1460 SQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPG 1519
S + S + ++ D RS+ L G+R +RG +
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDRMGRSRGRV----------PELPEKGSR-GSRGSQIDS 585
Query: 1520 SPVKRTWHRHLKDKLTHKEHN-HPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSL 1578
+H + + ++ E + +P R S RH R+ R ER QR S
Sbjct: 586 HSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGE--RDRRDNRERDQRPSS 643
Query: 1579 ERRHHSPS----------------------QRSHCSPSRKNHSSPSERSWRSPSQRNHCS 1616
RH + +R+ + ER R
Sbjct: 644 PIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREK 703
Query: 1617 PPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPS-- 1674
E ER +R R H ER E+ E R R
Sbjct: 704 ERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERE 763
Query: 1675 ---QRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSE 1731
+R ER+ ER + + +G +RR R R+P R H
Sbjct: 764 RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP-RDGHDERKS 822
Query: 1732 RSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSER--RHR------SPSERRHH 1783
+ + R+ SPS R+ SP R SP ++ S ++ +HR P E R
Sbjct: 823 KKRY----RNEGSPSPRQ--SPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSL 876
Query: 1784 SPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISE 1843
SPS + R+ S L E+ +R E S R +
Sbjct: 877 SPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQD 936
Query: 1844 -RSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGR---TSER 1899
H SE S + K P ++ G+ +G TSE
Sbjct: 937 IIGHHQSEDRETSDRAHDE--------NKKKAKIQKKPIKKKKEDDVGIERGNIETTSED 988
Query: 1900 SHRSSCERTRHSPS-EMRPGRPSGRNHCSPSERSRRSPLKEG 1940
S ++ + S E + + G + S E +++S K G
Sbjct: 989 GQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRG 1030
Score = 55.1 bits (131), Expect = 7e-07
Identities = 69/254 (27%), Positives = 93/254 (36%), Gaps = 23/254 (9%)
Query: 1620 RSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSP--SERSHRSSSERRHRSPSQRS 1677
R CH + +P H +H P ++ S S RS+RS + R RSPS S
Sbjct: 1158 RKCHRTRVEKVETP----HVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDS 1213
Query: 1678 -HRG---PSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERS 1733
HR S R S R R ++ + KR S + S R S RS
Sbjct: 1214 AHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDS-RS 1272
Query: 1734 HHSPSERSHHSPSERRHHSPS----ERSHCSPSER-SHCSPSERRHRSPSERRHHSPSEK 1788
H S R S+R+ HS S R +R H ER R +R ++K
Sbjct: 1273 H---SSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK 1329
Query: 1789 SHHSPSERSHHSPSERRRHSP----LERSRHSLLERSHRSPSERRSHRSFERSHRRISER 1844
+R ER R L+R R L+ S +R R+FE S +R
Sbjct: 1330 DWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKR 1389
Query: 1845 SHSPSEKSHLSPLE 1858
+ E H LE
Sbjct: 1390 CEAKLEGEHERDLE 1403
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 77.4 bits (189), Expect = 1e-13
Identities = 111/542 (20%), Positives = 158/542 (29%), Gaps = 106/542 (19%)
Query: 1480 KDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEH 1539
KD S+ + +F+ + +E +++S + G +LPG H+
Sbjct: 72 KDVSTENGHHFWSHPDREKEDEDVS------KEYGHLLPG----------------HRSQ 109
Query: 1540 NHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHS 1599
+H + G H R HR S E RHH PS RSH +H
Sbjct: 110 DHK--VGDEGVSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSH------SHQ 161
Query: 1600 SPSERSWRSPSQRNH-CSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPS 1658
E S +H R + G + + + + R S
Sbjct: 162 DEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGS 221
Query: 1659 ERSHRSSSERRHRSPSQRSHRGPSERSHCSPS------------ERRHRSPSQRSH---- 1702
E S H PS R H+G E E RH++ + H
Sbjct: 222 EEDEDVSDGHHHHGPSHR-HQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEE 280
Query: 1703 -RGPSERRHHSPSKRSHRSP--------------ARRSHRSPSERSHHSPS---ERSHHS 1744
S+ HH HRS ++HR R + E HH
Sbjct: 281 DEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHV 340
Query: 1745 PSERRH-HSPSERSHCSPSERSHCSPSERRHR--SPSERRHHSPSEKSHH--SPSERSHH 1799
P R H E +ER H P H E + H+ S R H
Sbjct: 341 PDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGHK 400
Query: 1800 S-------------PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRR---ISE 1843
S P P E E H++PS R+SH+ E H + I E
Sbjct: 401 SDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKE 460
Query: 1844 RSHSP------SEKSHL--SPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGR 1895
SH P ++SHL E + + H ++ + +H
Sbjct: 461 MSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEE 520
Query: 1896 TSERSHRSSC-----------ERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS 1944
E H S E E R R SP +EGL+
Sbjct: 521 DEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEED 580
Query: 1945 FP 1946
P
Sbjct: 581 EP 582
Score = 73.9 bits (180), Expect = 1e-12
Identities = 87/415 (20%), Positives = 122/415 (29%), Gaps = 78/415 (18%)
Query: 1573 SQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRN----------HCSPPERSC 1622
S+ +S E RHH S R H ++ + W P + H P RS
Sbjct: 50 SEEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQ 109
Query: 1623 -HSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGP 1681
H + + G+ G H R HR S+E RH PS RSH
Sbjct: 110 DHKVGDEGVS--------GEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQ 161
Query: 1682 SERSHCSPSERRHRSPSQRSHRG-------------PSERRHHSPSKRSHRSPARRSHRS 1728
E S H + HRG E + ++ H++ R H S
Sbjct: 162 DEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGS 221
Query: 1729 PSERS------HHSPSER--SHHSPS-----------------ERRHHSPSERSHCSPSE 1763
+ HH PS R H E RH + + H E
Sbjct: 222 EEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGH--GIE 279
Query: 1764 RSHCSPSERRHRSPSER-RHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSH 1822
HR PS R R H + S H + H E S H
Sbjct: 280 EDEDVSDGHHHRDPSHRHRSHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHH 339
Query: 1823 RSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSR------------CSPSERRGH 1870
+ HR E +ER H + H ++ + + RGH
Sbjct: 340 VPDHRHQGHRDEEEDEDVSTERWHQGPQHVHHGLVDEEEEEEEITVQFGHYVASHQPRGH 399
Query: 1871 SSSGKTCHS------PSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGR 1919
S + P HR P + ++E H++ R H E G+
Sbjct: 400 KSDEEDFQDEYKTEVPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQ 454
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapiens]
Length = 674
Score = 77.0 bits (188), Expect = 2e-13
Identities = 113/416 (27%), Positives = 150/416 (36%), Gaps = 43/416 (10%)
Query: 1545 YRERTPRG-----PSERTRHNPSWRNH-RSPSERSQRSSLERRHHSPSQRSHC----SPS 1594
+RE+ RG PS R +P++ + RSPSE S S R +P + S
Sbjct: 274 FREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFG 333
Query: 1595 RKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSH 1654
+ + + + + S PP + + G +P + + S S S
Sbjct: 334 GSDEEAAAAAAAAAASGVTTGKPP-----APPQPGGPAPGRNASARRRSSSSSSSSSASR 388
Query: 1655 RSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHS-- 1712
S S S RSSS R RS R RS S R RS S+R R S R HS
Sbjct: 389 TSSSRSSSRSSSRSRRGGGYYRSGRHARSRSR---SWSRSRSRSRRYSRSRSRGRRHSGG 445
Query: 1713 ---PSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSP 1769
R RSPARR P RS RSH RR R H S RS S
Sbjct: 446 GSRDGHRYSRSPARRGGYGPRRRSR----SRSHSGDRYRRG-GRGLRHHSSSRSRSSWSL 500
Query: 1770 SERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERR 1829
S R RS + R HSPS S S SPS L R S +E
Sbjct: 501 SPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPA 560
Query: 1830 SHRSFERSHRRISERSHSPSEKSHLSPLE--RSRCSPSERRGHSSSGKTCHSPSERSHRS 1887
+ + + ++ +P EK L + + ++ + H ER
Sbjct: 561 AGKETGAAKPKL-----TPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQEREDEL 615
Query: 1888 PSGMRQGRTSERSHRSSCER----TRHSPSEMRPGRPSGRNHCSPSERSR---RSP 1936
+ R+ R ER R ER ++S P R + S RSR RSP
Sbjct: 616 RAMARKIRMKERERREK-EREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSP 670
Score = 52.8 bits (125), Expect = 3e-06
Identities = 76/297 (25%), Positives = 95/297 (31%), Gaps = 16/297 (5%)
Query: 1660 RSHRSSSERRHRSPSQRSHRGPSERSHCSPS-ERRHRSPSQRSHRGPSERRHHSPSKRSH 1718
RS R E R + R PS SP+ + RSPS+ S S R +P R
Sbjct: 266 RSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPG-REE 324
Query: 1719 RSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPS 1778
+ S E + + + + + + +P + +P + S RR S S
Sbjct: 325 KITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNA----SARRRSSSS 380
Query: 1779 ERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSH 1838
S S S S S S S S RR RS RS R R + RS
Sbjct: 381 S----SSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSR 436
Query: 1839 RRISERSHSPSEKSHL---SPLERSRCSPSER---RGHSSSGKTCHSPSERSHRSPSGMR 1892
R S S H SP R P R R HS R H S
Sbjct: 437 SRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRS 496
Query: 1893 QGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGER 1949
S RS HSPS + S SPS R L GE+
Sbjct: 497 SWSLSPSRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEK 553
Score = 52.0 bits (123), Expect = 6e-06
Identities = 82/328 (25%), Positives = 123/328 (37%), Gaps = 40/328 (12%)
Query: 1430 GGTVQCRSAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKN 1489
GG R+A RR+ S S S A +T+S R SSSRS++
Sbjct: 363 GGPAPGRNASARRRSSS------------SSSSSSASRTSSSRSSSR-----SSSRSRRG 405
Query: 1490 --FYRN-------ETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHN 1540
+YR+ S S++ S +R ++RGR G R HR+ + +
Sbjct: 406 GGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGG-SRDGHRYSRSPARRGGYG 464
Query: 1541 HPSFYRERTPRGPSERT-----RHNPSWRNHRSPSERSQRS-SLER-RHHSPSQRSHCSP 1593
R R+ G R RH+ S R+ S S RS SL R R HSPS S
Sbjct: 465 PRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSR 524
Query: 1594 SRKNHSSPSERSWRSPSQRNHCSPP--ERSCHSLSERGLHSPSQRSHRGPSQR---RHHS 1648
SR SPS R R SP E+ + G + + + P ++ R
Sbjct: 525 SRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQK 584
Query: 1649 PSERSHRSPSERSHRSSSERRH-RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSE 1707
R ++ + + ++ H R + R + + ERR + + + +
Sbjct: 585 ALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQ 644
Query: 1708 RRHHSPSKRSHRSPARRSHRSPSERSHH 1735
R SP S +RR RS S H+
Sbjct: 645 SRSPSPRYSREYSSSRRRSRSRSRSPHY 672
>gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens]
Length = 299
Score = 75.9 bits (185), Expect = 4e-13
Identities = 55/215 (25%), Positives = 75/215 (34%), Gaps = 2/215 (0%)
Query: 1546 RERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERS 1605
R R P R P R+ +P R + R +P R +P ++ +P R
Sbjct: 84 RPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRD 143
Query: 1606 WRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERS--HR 1663
+P R+ +P R C + R +P R P R +P R +P R HR
Sbjct: 144 CETPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDLKHR 203
Query: 1664 SSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPAR 1723
HR HRG H HR HRG +H + HR P
Sbjct: 204 GLGTVIHRGLGTVIHRGLGTVKHRGLGTAIHRGLGTAIHRGLGTAKHRGLATAIHRGPGT 263
Query: 1724 RSHRSPSERSHHSPSERSHHSPSERRHHSPSERSH 1758
HR P+ H P+ H P+ H P H
Sbjct: 264 AIHRGPATAIHRGPATAIHRGPATAIHRGPGTAIH 298
Score = 73.2 bits (178), Expect = 2e-12
Identities = 51/184 (27%), Positives = 70/184 (38%), Gaps = 10/184 (5%)
Query: 1546 RERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERS 1605
R R P R P R+ +P R + R +P R +P ++ +P R
Sbjct: 116 RPRDCETPRPRDCDTPRPRDCETPRPRDCETPRPRDCDTPRPRDCDTPRPRDCDTPRPRD 175
Query: 1606 WRSPSQRNHCSPPERSCHS-----LSERGLHSPSQRS-----HRGPSQRRHHSPSERSHR 1655
+P R+ +P R C + L RGL + R HRG +H HR
Sbjct: 176 CDTPRPRDCDTPRPRDCDTPRPRDLKHRGLGTVIHRGLGTVIHRGLGTVKHRGLGTAIHR 235
Query: 1656 SPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSK 1715
HR +HR + HRGP H P+ HR P+ HRGP+ H P
Sbjct: 236 GLGTAIHRGLGTAKHRGLATAIHRGPGTAIHRGPATAIHRGPATAIHRGPATAIHRGPGT 295
Query: 1716 RSHR 1719
HR
Sbjct: 296 AIHR 299
Score = 70.1 bits (170), Expect = 2e-11
Identities = 57/232 (24%), Positives = 78/232 (33%), Gaps = 2/232 (0%)
Query: 1546 RERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERS 1605
R R P R P R+ +P R + R +P R +P ++ +P R
Sbjct: 68 RPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRD 127
Query: 1606 WRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSS 1665
+P R+ +P R C + R +P R P R +P R +P R +
Sbjct: 128 CDTPRPRDCETPRPRDCETPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTP 187
Query: 1666 SERRHRSPSQRS--HRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPAR 1723
R +P R HRG H HR HRG H HR
Sbjct: 188 RPRDCDTPRPRDLKHRGLGTVIHRGLGTVIHRGLGTVKHRGLGTAIHRGLGTAIHRGLGT 247
Query: 1724 RSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHR 1775
HR + H P H P+ H P+ H P+ H P HR
Sbjct: 248 AKHRGLATAIHRGPGTAIHRGPATAIHRGPATAIHRGPATAIHRGPGTAIHR 299
Score = 68.6 bits (166), Expect = 6e-11
Identities = 55/232 (23%), Positives = 78/232 (33%), Gaps = 2/232 (0%)
Query: 1561 PSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPER 1620
P R+ +P R + R +P R +P ++ +P R +P R+ +P R
Sbjct: 67 PRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPR 126
Query: 1621 SCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRG 1680
C + R +P R P R +P R +P R + R +P R
Sbjct: 127 DCDTPRPRDCETPRPRDCETPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDT 186
Query: 1681 PSERSHCSPSER--RHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPS 1738
P R +P R +HR HRG H HR HR H
Sbjct: 187 PRPRDCDTPRPRDLKHRGLGTVIHRGLGTVIHRGLGTVKHRGLGTAIHRGLGTAIHRGLG 246
Query: 1739 ERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSH 1790
H + H P H P+ H P+ HR P+ H P H
Sbjct: 247 TAKHRGLATAIHRGPGTAIHRGPATAIHRGPATAIHRGPATAIHRGPGTAIH 298
Score = 68.2 bits (165), Expect = 8e-11
Identities = 54/233 (23%), Positives = 77/233 (33%), Gaps = 2/233 (0%)
Query: 1568 SPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSE 1627
+P R + R +P R +P ++ +P R +P R+ +P R C +
Sbjct: 66 TPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRP 125
Query: 1628 RGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHC 1687
R +P R P R +P R +P R + R +P R P R
Sbjct: 126 RDCDTPRPRDCETPRPRDCETPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCD 185
Query: 1688 SPSERRHRSPSQRS--HRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSP 1745
+P R +P R HRG H HR HR H H
Sbjct: 186 TPRPRDCDTPRPRDLKHRGLGTVIHRGLGTVIHRGLGTVKHRGLGTAIHRGLGTAIHRGL 245
Query: 1746 SERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSH 1798
+H + H P H P+ HR P+ H P+ H P H
Sbjct: 246 GTAKHRGLATAIHRGPGTAIHRGPATAIHRGPATAIHRGPATAIHRGPGTAIH 298
Score = 61.6 bits (148), Expect = 7e-09
Identities = 51/228 (22%), Positives = 72/228 (31%), Gaps = 10/228 (4%)
Query: 1584 SPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQ 1643
+P R +P ++ +P R +P R+ +P R C + R +P R P
Sbjct: 66 TPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRP 125
Query: 1644 RRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHR 1703
R +P R +P R + R +P R P R +P R +P R
Sbjct: 126 RDCDTPRPRDCETPRPRDCETPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRDCD 185
Query: 1704 GPSERRHHSPSKRS----------HRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP 1753
P R +P R HR HR H H H
Sbjct: 186 TPRPRDCDTPRPRDLKHRGLGTVIHRGLGTVIHRGLGTVKHRGLGTAIHRGLGTAIHRGL 245
Query: 1754 SERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSP 1801
H + H P HR P+ H P+ H P+ H P
Sbjct: 246 GTAKHRGLATAIHRGPGTAIHRGPATAIHRGPATAIHRGPATAIHRGP 293
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 73.9 bits (180), Expect = 1e-12
Identities = 112/491 (22%), Positives = 174/491 (35%), Gaps = 103/491 (20%)
Query: 1497 SQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSER 1556
S + ++S G +++ RG I +P + R + P ++E R + R
Sbjct: 320 SDQKPSVSKSGRKIKGRGTIRYHTPPRS---RSCSESDDDDSSETPPHWKEEMQRLRAYR 376
Query: 1557 TRHNPSWR-------------NHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSE 1603
W + RS S+RS+ S + S H +K
Sbjct: 377 PPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKV 436
Query: 1604 RSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHR 1663
+ + ++ HC R H+ +RR PS+ S R +
Sbjct: 437 KHKKKGKKQKHC--------------------RRHKQTKKRRILIPSDIESSKSSTRRMK 476
Query: 1664 SS--SERRHRSPSQRSHRG------------PSERSHCSPSERRHRSPSQRSHRGPSERR 1709
SS ER RS S SH S +H S R +S SQ RG S R
Sbjct: 477 SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSR 536
Query: 1710 ------HHSPSKRSHRSPARRSHRSPSERS-HHSPSERSHHSPSE----RRHHSPSERSH 1758
HS S+ RS ++ HR + +S + S+ S + P + R + +E
Sbjct: 537 TASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVV 596
Query: 1759 CSP--------------SERSHCSPSERRHRSPSERRHHSPSEKSHHSPSER-------- 1796
P S P ++ + ER ++ +H P +
Sbjct: 597 VQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIK 656
Query: 1797 ---SHHSPSERRRHSPLERSRHSLL-----ERSHRSPSERRSHRSFERSHRR------IS 1842
S S +R ++S ++S +S E S RS S RS+ RS+ R
Sbjct: 657 ETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSH 716
Query: 1843 ERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSER--SHRSPSGMRQGRTSERS 1900
RS SPS +SH R++ S + SSS + S R R S ++ S +
Sbjct: 717 SRSRSPSSRSH----SRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKK 772
Query: 1901 HRSSCERTRHS 1911
H SS E+T HS
Sbjct: 773 HSSSSEKTLHS 783
Score = 73.6 bits (179), Expect = 2e-12
Identities = 179/864 (20%), Positives = 299/864 (34%), Gaps = 144/864 (16%)
Query: 1237 RSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNE------------------KRAKV 1278
+S D+ EK K + P H E + + S SES+ KR+K
Sbjct: 179 KSIKDVFEK-KRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKK 237
Query: 1279 RTKKTSDSKYPMKRITKRLRKH-RKFYTNSRTTIESPSRELAAHLRRKRIGATQTSTASL 1337
R K+ S S+ P + + H + TN + +++S ++ +R + I + L
Sbjct: 238 RRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENRFLL 297
Query: 1338 KR---------QPKKPSQPKFMQLLFQSLKRA-----------FQTAHRVIASVGRKPVD 1377
+R +PK P + S+ ++ + T R + D
Sbjct: 298 RRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPRSRSCSESDDDD 357
Query: 1378 GTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRS 1437
+ W + Q R Y PS K K DKL+ S+ E RS
Sbjct: 358 SSETPPHWKEE----MQRLRAYRPPSGEKWSK--GDKLSDPCSSRWDE----------RS 401
Query: 1438 AQQPRRAYSFQPRPLRLPKPTDS------QSGIAFQTASVGQPLRTVQKDSSSRSKKNFY 1491
Q R++S+ L S + + G+ + ++ ++ ++
Sbjct: 402 LSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILI 461
Query: 1492 RNETSSQESKNL----STPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRE 1547
++ S +S S R + KR W + KD + H+ YR
Sbjct: 462 PSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRS 521
Query: 1548 RT-----PRGPSERTRHNPSWRNHRSPSE-RSQRSSLERRHHSPSQRSHCSPSRKNHSSP 1601
++ RG S + S + RS S+ RS S R+ S S R S +N
Sbjct: 522 KSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVK 581
Query: 1602 SERSWRSPSQRNHC-----------------SPP-------ERSCHSLSERGLHSPSQRS 1637
+E + +Q + SPP ++ ER ++ +
Sbjct: 582 TEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTT 641
Query: 1638 HRGPSQRRHHSPSERSHRSPS-----ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSER 1692
H P Q + + + S S E++ S + + S P RS S S
Sbjct: 642 HLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRS 701
Query: 1693 RHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR--- 1749
RS ++ S R SPS RSH H S S ++ ++RR
Sbjct: 702 YSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRS 761
Query: 1750 ---HHSPSERSHCSPSERS-HCSPSERRHRSPSERRH-HSPSEKSHHSPSERSH----HS 1800
+S S + H S SE++ H + R RS R++ S S + S SE+S S
Sbjct: 762 SGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQSSVQATQS 821
Query: 1801 PSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERS 1860
E+ + +ER+ + + +R + +S R S +R + + S ++ P ++
Sbjct: 822 AQEKEKQGQMERTHNK--QEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKN 879
Query: 1861 RC-------SPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHS-- 1911
S SER +S H S++ + + SE H T+ S
Sbjct: 880 YAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSE-IHIKVKPTTKSSTN 938
Query: 1912 -----------PSEMRPGRPSGRNHCSPSERSRRSPL--KEGLKYSFPGERPSHSLSRDF 1958
S+ R CS SE +R P K G K + E + +
Sbjct: 939 TSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREH-TKKVKEKL 997
Query: 1959 KNQTTLLGTTHKNPKAGQV--WRP 1980
K + HK PK Q W+P
Sbjct: 998 KGKK---DKKHKAPKRKQAFHWQP 1018
Score = 69.7 bits (169), Expect = 3e-11
Identities = 105/405 (25%), Positives = 149/405 (36%), Gaps = 70/405 (17%)
Query: 1516 ILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSE---------RTRHNPSWRNH 1566
+L +K + + K K TH E + S + SE R +H +
Sbjct: 175 VLATKSIKDVFEKKRK-KPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVK 233
Query: 1567 RSPSERSQRSSLE--RRHHSPSQRSHC--SPSRKNHSSPSERSWRSPSQRNHCSPPERSC 1622
RS R + SS E R H+ + + H S + + S S P R PP
Sbjct: 234 RSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPEN 293
Query: 1623 HSLSERGLH------------------------SPSQRSHRGPSQRRHHSPSERSHRSPS 1658
L R + S S R +G R+H+P RS S
Sbjct: 294 RFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTPPR--SRSCS 351
Query: 1659 ERSHRSSSE------------RRHRSPS-QRSHRGPSERSHCSPSERRHRSPSQRSHRGP 1705
E SSE R +R PS ++ +G CS S RS SQRS R
Sbjct: 352 ESDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCS-SRWDERSLSQRS-RSW 409
Query: 1706 SERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERS 1765
S ++S + S + R + H ++ H RRH +R PS+
Sbjct: 410 SYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHC---RRHKQTKKRRILIPSDIE 466
Query: 1766 HCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSP 1825
S RR +S +R E+S S S SHH S +R S ++ S L S R
Sbjct: 467 SSKSSTRRMKSSCDR------ERSSRSSSLSSHH--SSKRDWSKSDKDVQSSLTHSSRDS 518
Query: 1826 SERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGH 1870
+SH +S+ R S RS + S+ S S RS+ S + GH
Sbjct: 519 YRSKSH---SQSYSRGSSRSRTASKSSSHS-RSRSKSRSSSKSGH 559
Score = 69.3 bits (168), Expect = 3e-11
Identities = 88/391 (22%), Positives = 141/391 (36%), Gaps = 52/391 (13%)
Query: 1622 CHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGP 1681
C L+ + + ++ + P+ H S+ S S S S SE H +R H+
Sbjct: 173 CGVLATKSIKDVFEKKRKKPT---HSEGSDSSSNSSSSSESSSESELEHERSRRRKHK-- 227
Query: 1682 SERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERS 1741
R S++R + S S P + +P S RS S P R
Sbjct: 228 -RRPKVKRSKKRRKEAS--SSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRP 284
Query: 1742 HHSPSE------RRHHSPSERSHCSP----------SERSHCSPSERRHRSPSERRHHSP 1785
P R P + P ++ S S R+ + R+H+P
Sbjct: 285 EEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRGTIRYHTP 344
Query: 1786 SEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERS-------- 1837
S SE SE H E R R++R PS + + + S
Sbjct: 345 PRS--RSCSESDDDDSSETPPHWKEEMQR----LRAYRPPSGEKWSKGDKLSDPCSSRWD 398
Query: 1838 HRRISERSHSPSEKSHLSPLERSRCSPSERR-------GHSSSGKT---CHSPSERSHRS 1887
R +S+RS S S + S L +R S ++ H GK C + R
Sbjct: 399 ERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRR 458
Query: 1888 ---PSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYS 1944
PS + ++S R +SSC+R R S S S + S S++ +S L + S
Sbjct: 459 ILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDS 518
Query: 1945 FPGERPSHSLSR-DFKNQTTLLGTTHKNPKA 1974
+ + S S SR +++T ++H ++
Sbjct: 519 YRSKSHSQSYSRGSSRSRTASKSSSHSRSRS 549
Score = 59.3 bits (142), Expect = 4e-08
Identities = 65/200 (32%), Positives = 84/200 (42%), Gaps = 22/200 (11%)
Query: 1620 RSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHR 1679
R L+ R + S + PS+ + RSPS +S ++ RHR+ S S+
Sbjct: 1282 RKTARLNRRPRNQESSSDEQTPSR-----DDDSQSRSPSRSRSKSETKSRHRTRSV-SYS 1335
Query: 1680 GPSERSHCSPSERRHRSPSQRSHRGPSER---RHHSPSKRSHRSPARRSHRSPSERSHHS 1736
RS S S R RS S+ RG R R S S RS++S R S RS S S +
Sbjct: 1336 HSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSH-RTSSRSRSRSSSYD 1394
Query: 1737 PSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSER 1796
P RS + + RS S+ H S R RS S R + S SE S
Sbjct: 1395 PHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNR-RSRSCRSYGSDSE----SDRSY 1449
Query: 1797 SHHSPSERRRHSPLERSRHS 1816
SHH SP E SR+S
Sbjct: 1450 SHH-------RSPSESSRYS 1462
Score = 58.5 bits (140), Expect = 6e-08
Identities = 76/250 (30%), Positives = 100/250 (40%), Gaps = 60/250 (24%)
Query: 1510 VQARGRILPGS---PVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNH 1566
++++ ++ PGS V++T +L + N S E+TP +R + S
Sbjct: 1266 IKSKNKVRPGSLFDEVRKT------ARLNRRPRNQESSSDEQTP------SRDDDS--QS 1311
Query: 1567 RSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLS 1626
RSPS +S + RH + S S SR S+ S RS RS
Sbjct: 1312 RSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRS--------------RSYSRSR 1357
Query: 1627 ERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSH-RGPSERS 1685
RG +S + R S R S +SHR+SS R RS S H R S
Sbjct: 1358 SRGWYSRGRTRSRSSSYR-------------SYKSHRTSSRSRSRSSSYDPHSRSRSYTY 1404
Query: 1686 HCSPSERRHRSPSQRS---HRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSH 1742
S R RS SQRS HRG S R RS + RS+ S SE S H
Sbjct: 1405 DSYYSRSRSRSRSQRSDSYHRGRSYNR---------RSRSCRSYGSDSESDR---SYSHH 1452
Query: 1743 HSPSERRHHS 1752
SPSE +S
Sbjct: 1453 RSPSESSRYS 1462
Score = 54.3 bits (129), Expect = 1e-06
Identities = 58/178 (32%), Positives = 70/178 (39%), Gaps = 10/178 (5%)
Query: 1692 RRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHH 1751
RR R+ S R S S RSP+R +S ++ H + S HS S R
Sbjct: 1289 RRPRNQESSSDEQTPSRDDDSQS----RSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSS 1344
Query: 1752 SPSERSHCSPSERSHCSPSERRHRS-PSERRHHSPSEKSHHSPSERSHHSPSERRRHSPL 1810
+ S RS RS S R RS S R + S S S S + P R R
Sbjct: 1345 TSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTY 1404
Query: 1811 ER--SRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKS---HLSPLERSRCS 1863
+ SR RS RS S R RS S S S S++S H SP E SR S
Sbjct: 1405 DSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS 1462
Score = 54.3 bits (129), Expect = 1e-06
Identities = 55/178 (30%), Positives = 72/178 (40%), Gaps = 14/178 (7%)
Query: 1760 SPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLE 1819
S E++ + + RSPS R S ++ H + S HS S R + RSR
Sbjct: 1297 SSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRS 1356
Query: 1820 RSHR--SPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTC 1877
RS S RS S RS++ S S S S P RSR + S ++
Sbjct: 1357 RSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSR 1416
Query: 1878 HSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRS 1935
S+ HR S R+ R S RS+ S E R S +H SPSE SR S
Sbjct: 1417 SQRSDSYHRGRSYNRRSR-SCRSYGSDSESDR-----------SYSHHRSPSESSRYS 1462
Score = 53.1 bits (126), Expect = 3e-06
Identities = 66/201 (32%), Positives = 89/201 (44%), Gaps = 28/201 (13%)
Query: 1663 RSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPS-KRSH-RS 1720
R ++ R +Q S E++ + + RSPS+ + ++ RH + S SH RS
Sbjct: 1282 RKTARLNRRPRNQES--SSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRS 1339
Query: 1721 PARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPS-- 1778
+R S S RS+ R +S R S S RS+ +SH + S R RS S
Sbjct: 1340 RSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSY-----KSHRTSSRSRSRSSSYD 1394
Query: 1779 -ERRHHSPSEKSHHSPS---ERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSF 1834
R S + S++S S RS S S R S RSR RS+ S SE S RS+
Sbjct: 1395 PHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSC---RSYGSDSE--SDRSY 1449
Query: 1835 ERSHRRISERSHSPSEKSHLS 1855
SH R SPSE S S
Sbjct: 1450 --SHHR------SPSESSRYS 1462
Score = 35.0 bits (79), Expect = 0.73
Identities = 42/122 (34%), Positives = 53/122 (43%), Gaps = 18/122 (14%)
Query: 1796 RSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSH---RSFERSHRRISERSHSPSEKS 1852
R+ S S+ + S + S+ RS RS SE +S RS SH R RS + S +S
Sbjct: 1292 RNQESSSDEQTPSRDDDSQSRSPSRS-RSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRS 1350
Query: 1853 HLSPLERSRCSPSERRGHSSSGKT-CHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHS 1911
S S RG S G+T S S RS++S RTS RS S HS
Sbjct: 1351 R-------SYSRSRSRGWYSRGRTRSRSSSYRSYKS------HRTSSRSRSRSSSYDPHS 1397
Query: 1912 PS 1913
S
Sbjct: 1398 RS 1399
>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
protein [Homo sapiens]
Length = 1463
Score = 73.2 bits (178), Expect = 2e-12
Identities = 75/267 (28%), Positives = 105/267 (39%), Gaps = 26/267 (9%)
Query: 1589 SHCSPSRKNHSSPSERSWRSPSQRN---HCSPPERSCHSLSERGLHSPSQRSHRGPSQRR 1645
S CS ++ PS + N HCS L++ + + SQ S
Sbjct: 723 SFCSDQNESEVEPSVNADLKQMNENSVTHCSENNMPSSDLADEKVETVSQPSE------- 775
Query: 1646 HHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGP 1705
SP + ++ R+ RS R SPS S ++R +SPS R G
Sbjct: 776 --SPKDTIDKTKKPRTRRS----RFHSPSTTW----SPNKDTPQEKKRPQSPSPRRETGK 825
Query: 1706 SERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERS 1765
R+ SPS ++ + R+ RS S + + R S S +R + R S S R
Sbjct: 826 ESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPRR 885
Query: 1766 HCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSH-RS 1824
S + RS + SP EKS ER +RR R+R RSH RS
Sbjct: 886 ETSRENK--RSQPRVKDSSPGEKSRSQSRERESDRDGQRRERE--RRTRKWSRSRSHSRS 941
Query: 1825 PSERRSHRSFERSHRRISERSHSPSEK 1851
PS R+ +S S RI S+SP K
Sbjct: 942 PSRCRT-KSKSSSFGRIDRDSYSPRWK 967
Score = 62.8 bits (151), Expect = 3e-09
Identities = 66/281 (23%), Positives = 111/281 (39%), Gaps = 19/281 (6%)
Query: 1532 DKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHC 1591
DK F+ T P++ T + +SPS R + R+ SPS ++
Sbjct: 782 DKTKKPRTRRSRFHSPSTTWSPNKDTPQEK--KRPQSPSPRRETGKESRKSQSPSPKNES 839
Query: 1592 SPSRKNHSSPS--------ERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQ 1643
+ RK S S R +S S + + R SLS R S+ + R +
Sbjct: 840 ARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR--RETSRENKRSQPR 897
Query: 1644 RRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHR 1703
+ SP E+S ER +RR R +R+ + RSH S S R R+ S+ S
Sbjct: 898 VKDSSPGEKSRSQSRERESDRDGQRRER--ERRTRKWSRSRSH-SRSPSRCRTKSKSSSF 954
Query: 1704 GPSERRHHSPS-KRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRH-HSPSERSHCSP 1761
G +R +SP K + R R + P +++ ++ E+ H ++ + +
Sbjct: 955 GRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDIHLDADDPNSAD 1014
Query: 1762 SERSHCSP--SERRHRSPSERRHHSPSEKSHHSPSERSHHS 1800
R+ C +E+ + P R + K H R+ +S
Sbjct: 1015 KHRNDCPNWITEKINSGPDPRTRNPEKLKESHWEENRNENS 1055
Score = 50.8 bits (120), Expect = 1e-05
Identities = 62/213 (29%), Positives = 84/213 (39%), Gaps = 26/213 (12%)
Query: 1705 PSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSER---SHHSPSER-RHHSPSERSHCS 1760
PSE SP ++ R+ RS HSPS + +P E+ R SPS R
Sbjct: 773 PSE----SPKDTIDKTKKPRTRRS----RFHSPSTTWSPNKDTPQEKKRPQSPSPRRETG 824
Query: 1761 PSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLER 1820
R SPS + + ++ S S K + R S S +R + R SL R
Sbjct: 825 KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRSESLSPR 884
Query: 1821 SHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSP 1880
R + R +RS R+ + SP EKS ER +RR +T
Sbjct: 885 -------RETSRENKRSQPRV--KDSSPGEKSRSQSRERESDRDGQRR--ERERRTRKWS 933
Query: 1881 SERSH-RSPSGMRQGRTSERSHRSSCERTRHSP 1912
RSH RSPS R S+ S +R +SP
Sbjct: 934 RSRSHSRSPSRCR--TKSKSSSFGRIDRDSYSP 964
Score = 47.4 bits (111), Expect = 1e-04
Identities = 94/432 (21%), Positives = 157/432 (36%), Gaps = 68/432 (15%)
Query: 1474 PLRTVQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDK 1533
P T+ K R++++ + + +++ S N TP Q + R SP + T K +
Sbjct: 777 PKDTIDKTKKPRTRRSRFHSPSTTW-SPNKDTP----QEKKRPQSPSPRRETGKESRKSQ 831
Query: 1534 LTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSP 1593
++ ++ + P + RSP + R S RR S S R S
Sbjct: 832 SPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRES--RRSESLSPRRETSR 889
Query: 1594 SRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERS 1653
K RS + SP E+S ER QR R ER
Sbjct: 890 ENK----------RSQPRVKDSSPGEKSRSQSRERESDRDGQRRER-----------ERR 928
Query: 1654 HRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPS-ERRHRSPSQRSHRGPSERRHHS 1712
R S S S R R+ S+ S G +R SP + R + R RG R +
Sbjct: 929 TRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSYSPRWKGRWANDGWRCPRGNDRYRKND 988
Query: 1713 PSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSP---SERSHCSPSERSHCSP 1769
P K++ + R ++ P+ H R+ P +E+ + P R+ +P
Sbjct: 989 PEKQNENT---RKEKNDIHLDADDPNSADKH-----RNDCPNWITEKINSGPDPRTR-NP 1039
Query: 1770 SERRHRSPSERRHHSP--SEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERS-----H 1822
+ + E R+ + S + S+ R RS + +++ +
Sbjct: 1040 EKLKESHWEENRNENSGNSWNKNFGSGWVSNRGRGRGNRGRGTYRSSFAYKDQNENRWQN 1099
Query: 1823 RSPSERRSHRSFERSHRRISERSH---SPSEKSHLSPLERS-----------RCSPSE-- 1866
R P S+ S S + + ++S+ S E S +P +RS + P++
Sbjct: 1100 RKPLSGNSNSSGSESFKFVEQQSYKRKSEQEFSFDTPADRSGWTSASSWAVRKTLPADVQ 1159
Query: 1867 ----RRGHSSSG 1874
RRG +SSG
Sbjct: 1160 NYYSRRGRNSSG 1171
Score = 33.9 bits (76), Expect = 1.6
Identities = 37/152 (24%), Positives = 59/152 (38%), Gaps = 12/152 (7%)
Query: 1197 SQRKAKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEF 1256
+ K + +Q S+SP TID P + ++ EK + ++P
Sbjct: 763 ADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKDTPQEKKRPQSPSPRRE 822
Query: 1257 TQVHNLPESDSESTQNEKRAKVRTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSR 1316
T ES + + K R +K S S+ P K I + R+ + TT ES
Sbjct: 823 TG----KESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRSPKRDTTRESRRS 878
Query: 1317 ELAAHLRRKRIGATQTSTASLKRQPK-KPSQP 1347
E + R +TS + + QP+ K S P
Sbjct: 879 ESLSPRR-------ETSRENKRSQPRVKDSSP 903
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 72.4 bits (176), Expect = 4e-12
Identities = 107/412 (25%), Positives = 159/412 (38%), Gaps = 72/412 (17%)
Query: 1532 DKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLE-RRHHSPSQRSH 1590
++ HKE N S R G + R+P+E + S LE ++ H ++
Sbjct: 456 NEFIHKEQNSLSLLEAREADGDVVNEKK-------RTPNETT--SVLEPKKEHKEKEKQG 506
Query: 1591 CSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPS 1650
S S + S S + R+ S + S S S S R S RS P +++ HS S
Sbjct: 507 RSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSR----TSSRSS-SPKRKKRHSRS 561
Query: 1651 ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRH 1710
RSP+ ++ RS R RS S+R + S R+ +RR RS+R ER
Sbjct: 562 ----RSPTIKARRS----RSRSYSRRI-KIESNRARVKIRDRR------RSNRNSIERE- 605
Query: 1711 HSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770
+R +RSP+R RS S RS + R+ S S R +R + S + H +
Sbjct: 606 ----RRRNRSPSRERRRSRS-RSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
Query: 1771 ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRS 1830
+ + R R K ER E+++ E + R +R S
Sbjct: 661 KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKR---EEKDFKFSSQDDRLKRKRES 717
Query: 1831 HRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSG 1890
R+F RS S S H S + + + + + HS S +
Sbjct: 718 ERTFSRSG------SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSS-------------- 757
Query: 1891 MRQGRTSERSHRSSCE---------RTRHSPSEMRPGRPSGRNHCSPSERSR 1933
GR+S S SS E R+R R G+ + R H S S RSR
Sbjct: 758 ---GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS-RSR 805
Score = 64.3 bits (155), Expect = 1e-09
Identities = 84/342 (24%), Positives = 133/342 (38%), Gaps = 27/342 (7%)
Query: 1467 QTASVGQPLRT-VQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRT 1525
+T SV +P + +K+ RS+ + +SS S+ ST T + GS RT
Sbjct: 488 ETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGS--SRT 545
Query: 1526 WHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSP 1585
R K K H+ R R+P + R+R R + S R++ +RR
Sbjct: 546 SSRSSSPK-RKKRHS-----RSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRR--- 596
Query: 1586 SQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRR 1645
S R+ R+ + SPS RS S RS + R S S+ + QR
Sbjct: 597 SNRNSIERERRRNRSPSRERRRSRS---------RSRDRRTNRASRSRSRDRRKIDDQRG 647
Query: 1646 HHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGP 1705
+ S + H+ ++ R R ++ ER E++ R ++ +
Sbjct: 648 NLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE--EKDFKFS 705
Query: 1706 SERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERS 1765
S+ + S R+ +R S H S + + + + HS S+ S S SE S
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE-S 764
Query: 1766 HCSPSERRHRSPSERRHHSPSEKSHHS--PSERSHHSPSERR 1805
S E++ + P R S EKS S + R H S S R
Sbjct: 765 PGSSKEKKAKKPKHSRSRSV-EKSQRSGKKASRKHKSKSRSR 805
Score = 43.1 bits (100), Expect = 0.003
Identities = 61/263 (23%), Positives = 93/263 (35%), Gaps = 21/263 (7%)
Query: 1728 SPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSE 1787
S ERS SE S E RH ++ E+ +++ ++ E
Sbjct: 396 SEDERSDRG-SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKE 454
Query: 1788 KSHHSPSERSHHSPSERR----------RHSPLERSRHSLLERSHRSPSERRSHRSFERS 1837
+ E++ S E R + +P E + ++ H+ ++ RS S
Sbjct: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSS 514
Query: 1838 HRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTS 1897
S S + S S +S S S S R SS RS R+ R+
Sbjct: 515 SGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSR 574
Query: 1898 ERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPG-----ERPSH 1952
S R E R + ++R R S RN R RSP +E + R S
Sbjct: 575 SYSRRIKIESNR-ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASR 633
Query: 1953 SLSRDFK----NQTTLLGTTHKN 1971
S SRD + + L G +HK+
Sbjct: 634 SRSRDRRKIDDQRGNLSGNSHKH 656
Score = 43.1 bits (100), Expect = 0.003
Identities = 88/460 (19%), Positives = 161/460 (35%), Gaps = 81/460 (17%)
Query: 1260 HNLPESDSESTQNEKRAKV-RTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSREL 1318
H + + + EK ++ K+ + K +R+TK + + NS + +E+ +
Sbjct: 417 HRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADG 476
Query: 1319 AAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGR-KPVD 1377
+KR TS K++ K+ + Q R+ ++ +S R
Sbjct: 477 DVVNEKKRTPNETTSVLEPKKEHKEKEK--------QGRSRSGSSSSGSSSSNSRTSSTS 528
Query: 1378 GTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRS 1437
T + ++S + + ++R SS KR KR + +P T++ R
Sbjct: 529 STVSSSSYSSSSGSSRTSSRS----SSPKRKKRHSRSRSP--------------TIKARR 570
Query: 1438 AQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSS 1497
++ R+YS R K +++ + R ++ RN
Sbjct: 571 SRS--RSYS------RRIKIESNRARVKI------------------RDRRRSNRNSIER 604
Query: 1498 QESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERT 1557
+ +N S R ++R R S +RT N S R R R ++
Sbjct: 605 ERRRNRSPSRERRRSRSR----SRDRRT--------------NRASRSRSRDRRKIDDQ- 645
Query: 1558 RHNPSWRNHRSPSERSQRSSLERRHHS--------PSQRSHCSPSRKNHSSPSERSWRSP 1609
R N S +H+ E ++ + R S +R RK E+ ++
Sbjct: 646 RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
Query: 1610 SQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERR 1669
SQ + S + S G S H + + + S S+ S RSSSE
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
Query: 1670 HRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERR 1709
S +++ + RS +R + R H+ S R
Sbjct: 766 GSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 72.4 bits (176), Expect = 4e-12
Identities = 107/412 (25%), Positives = 159/412 (38%), Gaps = 72/412 (17%)
Query: 1532 DKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLE-RRHHSPSQRSH 1590
++ HKE N S R G + R+P+E + S LE ++ H ++
Sbjct: 456 NEFIHKEQNSLSLLEAREADGDVVNEKK-------RTPNETT--SVLEPKKEHKEKEKQG 506
Query: 1591 CSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPS 1650
S S + S S + R+ S + S S S S R S RS P +++ HS S
Sbjct: 507 RSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSR----TSSRSS-SPKRKKRHSRS 561
Query: 1651 ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRH 1710
RSP+ ++ RS R RS S+R + S R+ +RR RS+R ER
Sbjct: 562 ----RSPTIKARRS----RSRSYSRRI-KIESNRARVKIRDRR------RSNRNSIERE- 605
Query: 1711 HSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPS 1770
+R +RSP+R RS S RS + R+ S S R +R + S + H +
Sbjct: 606 ----RRRNRSPSRERRRSRS-RSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEA 660
Query: 1771 ERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRS 1830
+ + R R K ER E+++ E + R +R S
Sbjct: 661 KEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKR---EEKDFKFSSQDDRLKRKRES 717
Query: 1831 HRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSG 1890
R+F RS S S H S + + + + + HS S +
Sbjct: 718 ERTFSRSG------SISVKIIRHDSRQDSKKSTTKDSKKHSGSDSS-------------- 757
Query: 1891 MRQGRTSERSHRSSCE---------RTRHSPSEMRPGRPSGRNHCSPSERSR 1933
GR+S S SS E R+R R G+ + R H S S RSR
Sbjct: 758 ---GRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKS-RSR 805
Score = 64.3 bits (155), Expect = 1e-09
Identities = 84/342 (24%), Positives = 133/342 (38%), Gaps = 27/342 (7%)
Query: 1467 QTASVGQPLRT-VQKDSSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRT 1525
+T SV +P + +K+ RS+ + +SS S+ ST T + GS RT
Sbjct: 488 ETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGS--SRT 545
Query: 1526 WHRHLKDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSP 1585
R K K H+ R R+P + R+R R + S R++ +RR
Sbjct: 546 SSRSSSPK-RKKRHS-----RSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRR--- 596
Query: 1586 SQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRR 1645
S R+ R+ + SPS RS S RS + R S S+ + QR
Sbjct: 597 SNRNSIERERRRNRSPSRERRRSRS---------RSRDRRTNRASRSRSRDRRKIDDQRG 647
Query: 1646 HHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGP 1705
+ S + H+ ++ R R ++ ER E++ R ++ +
Sbjct: 648 NLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKRE--EKDFKFS 705
Query: 1706 SERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERS 1765
S+ + S R+ +R S H S + + + + HS S+ S S SE S
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSE-S 764
Query: 1766 HCSPSERRHRSPSERRHHSPSEKSHHS--PSERSHHSPSERR 1805
S E++ + P R S EKS S + R H S S R
Sbjct: 765 PGSSKEKKAKKPKHSRSRSV-EKSQRSGKKASRKHKSKSRSR 805
Score = 43.1 bits (100), Expect = 0.003
Identities = 61/263 (23%), Positives = 93/263 (35%), Gaps = 21/263 (7%)
Query: 1728 SPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSE 1787
S ERS SE S E RH ++ E+ +++ ++ E
Sbjct: 396 SEDERSDRG-SESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKE 454
Query: 1788 KSHHSPSERSHHSPSERR----------RHSPLERSRHSLLERSHRSPSERRSHRSFERS 1837
+ E++ S E R + +P E + ++ H+ ++ RS S
Sbjct: 455 MNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGRSRSGSSS 514
Query: 1838 HRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQGRTS 1897
S S + S S +S S S S R SS RS R+ R+
Sbjct: 515 SGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRKKRHSRSRSPTIKARRSRSR 574
Query: 1898 ERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPG-----ERPSH 1952
S R E R + ++R R S RN R RSP +E + R S
Sbjct: 575 SYSRRIKIESNR-ARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASR 633
Query: 1953 SLSRDFK----NQTTLLGTTHKN 1971
S SRD + + L G +HK+
Sbjct: 634 SRSRDRRKIDDQRGNLSGNSHKH 656
Score = 43.1 bits (100), Expect = 0.003
Identities = 88/460 (19%), Positives = 161/460 (35%), Gaps = 81/460 (17%)
Query: 1260 HNLPESDSESTQNEKRAKV-RTKKTSDSKYPMKRITKRLRKHRKFYTNSRTTIESPSREL 1318
H + + + EK ++ K+ + K +R+TK + + NS + +E+ +
Sbjct: 417 HRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADG 476
Query: 1319 AAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAHRVIASVGR-KPVD 1377
+KR TS K++ K+ + Q R+ ++ +S R
Sbjct: 477 DVVNEKKRTPNETTSVLEPKKEHKEKEK--------QGRSRSGSSSSGSSSSNSRTSSTS 528
Query: 1378 GTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRS 1437
T + ++S + + ++R SS KR KR + +P T++ R
Sbjct: 529 STVSSSSYSSSSGSSRTSSRS----SSPKRKKRHSRSRSP--------------TIKARR 570
Query: 1438 AQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSS 1497
++ R+YS R K +++ + R ++ RN
Sbjct: 571 SRS--RSYS------RRIKIESNRARVKI------------------RDRRRSNRNSIER 604
Query: 1498 QESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSFYRERTPRGPSERT 1557
+ +N S R ++R R S +RT N S R R R ++
Sbjct: 605 ERRRNRSPSRERRRSRSR----SRDRRT--------------NRASRSRSRDRRKIDDQ- 645
Query: 1558 RHNPSWRNHRSPSERSQRSSLERRHHS--------PSQRSHCSPSRKNHSSPSERSWRSP 1609
R N S +H+ E ++ + R S +R RK E+ ++
Sbjct: 646 RGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFS 705
Query: 1610 SQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERR 1669
SQ + S + S G S H + + + S S+ S RSSSE
Sbjct: 706 SQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESP 765
Query: 1670 HRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERR 1709
S +++ + RS +R + R H+ S R
Sbjct: 766 GSSKEKKAKKPKHSRSRSVEKSQRSGKKASRKHKSKSRSR 805
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 71.6 bits (174), Expect = 7e-12
Identities = 76/307 (24%), Positives = 113/307 (36%), Gaps = 34/307 (11%)
Query: 1672 SPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSH-RSPARRSHRSPS 1730
S +G RSH R S S R S+ +H S RSH RS +R+ R S
Sbjct: 297 SGKSNERKGGRSRSHTRSKSRS--SSKSHSRRKRSQSKHRS---RSHNRSRSRQKDRRRS 351
Query: 1731 ERSHHSPSERSHHSPSERRHHSP----------SERSHCSPSERSHCSPSERRHRSPSER 1780
+ H S+ S R HS E+ +R E+ ER
Sbjct: 352 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER 411
Query: 1781 RHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRR 1840
+ +K E+ ER R E+ R E+ ER RS E +R
Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 471
Query: 1841 ISE-------RSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQ 1893
+ RS++ S +S S ER R R S S +T + +S RSPS +
Sbjct: 472 KKDKKSRTPPRSYNASRRSRSSSRERRR---RRSRSSSRSPRTSKTIKRKSSRSPSPRSR 528
Query: 1894 GRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKE---GLKYSFPGERP 1950
+ ++ E+ R SE R S S ++R + L++ LK + P
Sbjct: 529 NKKDKKR-----EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEP 583
Query: 1951 SHSLSRD 1957
S+S++
Sbjct: 584 DSSVSKE 590
Score = 65.5 bits (158), Expect = 5e-10
Identities = 73/321 (22%), Positives = 116/321 (36%), Gaps = 29/321 (9%)
Query: 1485 RSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSF 1544
R ++F + K+ G R ++ R S K H + K + +H S
Sbjct: 283 REAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKS----HSRRKRSQSKHRSRSH 338
Query: 1545 YRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSER 1604
R R+ R R +P + +S R RS R HS +R K E+
Sbjct: 339 NRSRS-RQKDRRRSKSPHKKRSKSRERRKSRS----RSHSRDKRKDTREKIKEKERVKEK 393
Query: 1605 SWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS 1664
+R E+ ERG + + ++ ER E+
Sbjct: 394 DREKERER------EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 447
Query: 1665 SSERRHRSPSQRSHRGPSERSHCSPSERRHRSP------SQRSHRGPSERRHHSPSKRSH 1718
E+ +R E +++ R+P S+RS ERR S+ S
Sbjct: 448 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR-SRSSS 506
Query: 1719 RSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPS 1778
RSP R+ ++ +S SPS RS + ++R ER H SER S +S +
Sbjct: 507 RSP--RTSKTIKRKSSRSPSPRSRNKKDKKRE---KERDHI--SERRERERSTSMRKSSN 559
Query: 1779 ERRHHSPSEKSHHSPSERSHH 1799
+R EK+ S E+ H+
Sbjct: 560 DRDGKEKLEKNSTSLKEKEHN 580
Score = 62.4 bits (150), Expect = 4e-09
Identities = 74/341 (21%), Positives = 111/341 (32%), Gaps = 28/341 (8%)
Query: 1550 PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSP 1609
P R R+H RS S RR S S+ S +R R +SP
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 1610 SQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERR 1669
++ S R S S HS +R + E+ ER E+
Sbjct: 355 HKKRSKSRERRKSRSRS----HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 410
Query: 1670 HRSPSQRSHRGPSERSHCSPSER-RHRSPSQRSHRGPSERRHHSPSKRSHRSPARR--SH 1726
R +R +R R R R + + K + ++
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 1727 RSPSERSHHSP-----SERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERR 1781
R ++S P S RS S ERR S S R+ + + RSPS R
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR---SPRTSKTIKRKSSRSPSPR- 526
Query: 1782 HHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRI 1841
S ++K ER H SERR ER R + + +S ++R E++ +
Sbjct: 527 --SRNKKDKKREKERDH--ISERR-----ERERSTSM---RKSSNDRDGKEKLEKNSTSL 574
Query: 1842 SERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSE 1882
E+ H+ S +S + +P C E
Sbjct: 575 KEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEE 615
Score = 32.7 bits (73), Expect = 3.6
Identities = 35/131 (26%), Positives = 45/131 (34%), Gaps = 15/131 (11%)
Query: 1818 LERSHRSPSERRS--HRSFERSHRRISERSHSPSEKSHLSPLERSR-----CSPSERRGH 1870
+E +ER+ RS RS R S +SHS ++S RS RR
Sbjct: 293 IEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 352
Query: 1871 SSSGKTCHSPSERSHRSPSGMRQGR--------TSERSHRSSCERTRHSPSEMRPGRPSG 1922
S K S R RS S R R ER E+ R E + G
Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG 412
Query: 1923 RNHCSPSERSR 1933
+N ER +
Sbjct: 413 KNKDRDKEREK 423
Score = 32.0 bits (71), Expect = 6.2
Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 8/126 (6%)
Query: 1174 KRSQISKYRERDRPVIRRSPISPSQRKAKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIR 1233
K+ + S+ R RRS S +R+ + +S+SP ++ ++ S+SP+P
Sbjct: 472 KKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP------ 525
Query: 1234 RGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKRAKVRT--KKTSDSKYPMK 1291
R + + EK + E + ++ +S ++ EK K T K+ +K P
Sbjct: 526 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 585
Query: 1292 RITKRL 1297
++K +
Sbjct: 586 SVSKEV 591
Score = 31.6 bits (70), Expect = 8.1
Identities = 33/103 (32%), Positives = 41/103 (39%), Gaps = 9/103 (8%)
Query: 1841 ISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERS---HRSPSGMR-QGRT 1896
IS S KS+ RSR S R S S HS +RS HRS S R + R
Sbjct: 289 ISAAIEPESGKSNERKGGRSR---SHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ 345
Query: 1897 SERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKE 1939
+R S + R E R R R+H + R +KE
Sbjct: 346 KDRRRSKSPHKKRSKSRERRKSR--SRSHSRDKRKDTREKIKE 386
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
sapiens]
Length = 508
Score = 71.6 bits (174), Expect = 7e-12
Identities = 76/307 (24%), Positives = 113/307 (36%), Gaps = 34/307 (11%)
Query: 1672 SPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSH-RSPARRSHRSPS 1730
S +G RSH R S S R S+ +H S RSH RS +R+ R S
Sbjct: 181 SGKSNERKGGRSRSHTRSKSRS--SSKSHSRRKRSQSKHRS---RSHNRSRSRQKDRRRS 235
Query: 1731 ERSHHSPSERSHHSPSERRHHSP----------SERSHCSPSERSHCSPSERRHRSPSER 1780
+ H S+ S R HS E+ +R E+ ER
Sbjct: 236 KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKER 295
Query: 1781 RHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRR 1840
+ +K E+ ER R E+ R E+ ER RS E +R
Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKR 355
Query: 1841 ISE-------RSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQ 1893
+ RS++ S +S S ER R R S S +T + +S RSPS +
Sbjct: 356 KKDKKSRTPPRSYNASRRSRSSSRERRR---RRSRSSSRSPRTSKTIKRKSSRSPSPRSR 412
Query: 1894 GRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKE---GLKYSFPGERP 1950
+ ++ E+ R SE R S S ++R + L++ LK + P
Sbjct: 413 NKKDKKR-----EKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEP 467
Query: 1951 SHSLSRD 1957
S+S++
Sbjct: 468 DSSVSKE 474
Score = 65.5 bits (158), Expect = 5e-10
Identities = 73/321 (22%), Positives = 116/321 (36%), Gaps = 29/321 (9%)
Query: 1485 RSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSF 1544
R ++F + K+ G R ++ R S K H + K + +H S
Sbjct: 167 REAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKS----HSRRKRSQSKHRSRSH 222
Query: 1545 YRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSER 1604
R R+ R R +P + +S R RS R HS +R K E+
Sbjct: 223 NRSRS-RQKDRRRSKSPHKKRSKSRERRKSRS----RSHSRDKRKDTREKIKEKERVKEK 277
Query: 1605 SWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS 1664
+R E+ ERG + + ++ ER E+
Sbjct: 278 DREKERER------EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDK 331
Query: 1665 SSERRHRSPSQRSHRGPSERSHCSPSERRHRSP------SQRSHRGPSERRHHSPSKRSH 1718
E+ +R E +++ R+P S+RS ERR S+ S
Sbjct: 332 EKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR-SRSSS 390
Query: 1719 RSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPS 1778
RSP R+ ++ +S SPS RS + ++R ER H SER S +S +
Sbjct: 391 RSP--RTSKTIKRKSSRSPSPRSRNKKDKKRE---KERDHI--SERRERERSTSMRKSSN 443
Query: 1779 ERRHHSPSEKSHHSPSERSHH 1799
+R EK+ S E+ H+
Sbjct: 444 DRDGKEKLEKNSTSLKEKEHN 464
Score = 62.4 bits (150), Expect = 4e-09
Identities = 74/341 (21%), Positives = 111/341 (32%), Gaps = 28/341 (8%)
Query: 1550 PRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSRKNHSSPSERSWRSP 1609
P R R+H RS S RR S S+ S +R R +SP
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 1610 SQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERR 1669
++ S R S S HS +R + E+ ER E+
Sbjct: 239 HKKRSKSRERRKSRSRS----HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 294
Query: 1670 HRSPSQRSHRGPSERSHCSPSER-RHRSPSQRSHRGPSERRHHSPSKRSHRSPARR--SH 1726
R +R +R R R R + + K + ++
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 1727 RSPSERSHHSP-----SERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERR 1781
R ++S P S RS S ERR S S R+ + + RSPS R
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSR---SPRTSKTIKRKSSRSPSPR- 410
Query: 1782 HHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRI 1841
S ++K ER H SERR ER R + + +S ++R E++ +
Sbjct: 411 --SRNKKDKKREKERDH--ISERR-----ERERSTSM---RKSSNDRDGKEKLEKNSTSL 458
Query: 1842 SERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSE 1882
E+ H+ S +S + +P C E
Sbjct: 459 KEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEE 499
Score = 32.7 bits (73), Expect = 3.6
Identities = 35/131 (26%), Positives = 45/131 (34%), Gaps = 15/131 (11%)
Query: 1818 LERSHRSPSERRS--HRSFERSHRRISERSHSPSEKSHLSPLERSR-----CSPSERRGH 1870
+E +ER+ RS RS R S +SHS ++S RS RR
Sbjct: 177 IEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 236
Query: 1871 SSSGKTCHSPSERSHRSPSGMRQGR--------TSERSHRSSCERTRHSPSEMRPGRPSG 1922
S K S R RS S R R ER E+ R E + G
Sbjct: 237 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG 296
Query: 1923 RNHCSPSERSR 1933
+N ER +
Sbjct: 297 KNKDRDKEREK 307
Score = 32.0 bits (71), Expect = 6.2
Identities = 28/126 (22%), Positives = 56/126 (44%), Gaps = 8/126 (6%)
Query: 1174 KRSQISKYRERDRPVIRRSPISPSQRKAKIYTQASKSPTSTIDLQSGPSQSPAPVQVYIR 1233
K+ + S+ R RRS S +R+ + +S+SP ++ ++ S+SP+P
Sbjct: 356 KKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP------ 409
Query: 1234 RGQRSRPDLVEKTKTRAPGHYEFTQVHNLPESDSESTQNEKRAKVRT--KKTSDSKYPMK 1291
R + + EK + E + ++ +S ++ EK K T K+ +K P
Sbjct: 410 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS 469
Query: 1292 RITKRL 1297
++K +
Sbjct: 470 SVSKEV 475
Score = 31.6 bits (70), Expect = 8.1
Identities = 33/103 (32%), Positives = 41/103 (39%), Gaps = 9/103 (8%)
Query: 1841 ISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERS---HRSPSGMR-QGRT 1896
IS S KS+ RSR S R S S HS +RS HRS S R + R
Sbjct: 173 ISAAIEPESGKSNERKGGRSR---SHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQ 229
Query: 1897 SERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKE 1939
+R S + R E R R R+H + R +KE
Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSR--SRSHSRDKRKDTREKIKE 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.127 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,842,715
Number of Sequences: 37866
Number of extensions: 4853363
Number of successful extensions: 32516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 671
Number of HSP's that attempted gapping in prelim test: 16396
Number of HSP's gapped (non-prelim): 6072
length of query: 1984
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1867
effective length of database: 13,817,196
effective search space: 25796704932
effective search space used: 25796704932
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.