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Search of human proteins with 152963644
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|152963644 paired-like homeodomain transcription factor 1
[Homo sapiens]
(314 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|152963644 paired-like homeodomain transcription factor 1 [Hom... 652 0.0
gi|21361183 paired-like homeodomain transcription factor 2 isofo... 364 e-101
gi|24234708 paired-like homeodomain transcription factor 2 isofo... 362 e-100
gi|24234711 paired-like homeodomain transcription factor 2 isofo... 360 e-100
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 280 9e-76
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 115 4e-26
gi|24497589 aristaless related homeobox [Homo sapiens] 105 7e-23
gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens] 104 9e-23
gi|113204604 aristaless-like homeobox 3 [Homo sapiens] 103 3e-22
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 103 3e-22
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 101 8e-22
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 101 1e-21
gi|14149760 orthopedia homeobox [Homo sapiens] 101 1e-21
gi|7706659 paired related homeobox 2 [Homo sapiens] 100 1e-21
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 99 5e-21
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 99 5e-21
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 99 5e-21
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 97 2e-20
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 97 2e-20
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 97 2e-20
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 97 2e-20
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 97 2e-20
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 97 2e-20
gi|20070107 orthodenticle homeobox 1 [Homo sapiens] 93 3e-19
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 92 6e-19
gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Hom... 92 8e-19
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 92 8e-19
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 91 1e-18
gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] 89 7e-18
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 88 1e-17
>gi|152963644 paired-like homeodomain transcription factor 1 [Homo
sapiens]
Length = 314
Score = 652 bits (1681), Expect = 0.0
Identities = 314/314 (100%), Positives = 314/314 (100%)
Query: 1 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKER 60
MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKER
Sbjct: 1 MDAFKGGMSLERLPEGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKER 60
Query: 61 GGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMRE 120
GGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMRE
Sbjct: 61 GGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMRE 120
Query: 121 EIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYS 180
EIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYS
Sbjct: 121 EIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYS 180
Query: 181 YNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNS 240
YNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNS
Sbjct: 181 YNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNS 240
Query: 241 GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGL 300
GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGL
Sbjct: 241 GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGL 300
Query: 301 QGPASGLNACQYNS 314
QGPASGLNACQYNS
Sbjct: 301 QGPASGLNACQYNS 314
>gi|21361183 paired-like homeodomain transcription factor 2 isoform
c [Homo sapiens]
Length = 324
Score = 364 bits (935), Expect = e-101
Identities = 203/331 (61%), Positives = 234/331 (70%), Gaps = 32/331 (9%)
Query: 1 MDAFKGGMSLERLPEGLRPPPPP------PHDMGPAFHLARPADPREPLENSA------- 47
M+ KG + LE G + P + A LA P PR L++S
Sbjct: 1 MNCMKGPLHLEHRAAGTKLSAVSSSSCHHPQPLAMASVLA-PGQPRS-LDSSKHRLEVHT 58
Query: 48 -SESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEA 106
S++S E EK++ + K + GA+DP+KKK+QRRQRTHFTSQQLQELEA
Sbjct: 59 ISDTSSPEAAEKDKSQQGKNEDV---------GAEDPSKKKRQRRQRTHFTSQQLQELEA 109
Query: 107 TFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSG 166
TFQRNRYPDMS REEIAVWTNLTE RVRVWFKNRRAKWRKRERNQQ +LCK G+ PQF+G
Sbjct: 110 TFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNG 169
Query: 167 LVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSM--SPLSSQSMFSAPSSISSMT 224
L+QPY+D+Y GYSYNNWAAK L A LSTKSF FFNSM +PLSSQSMFS P+SISSM+
Sbjct: 170 LMQPYDDMY-PGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMS 228
Query: 225 MPSSMGPGAVPGMPNS---GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSS 281
M SSM P AV G+P S LNN+NNL+ SLNSA+ ACPY P PY VYRDTCNSS
Sbjct: 229 MSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTCNSS 287
Query: 282 LASLRLKSKQHSSFGYGGLQGPASGLNACQY 312
LASLRLK+KQHSSFGY +Q PAS L+ACQY
Sbjct: 288 LASLRLKAKQHSSFGYASVQNPASNLSACQY 318
>gi|24234708 paired-like homeodomain transcription factor 2 isoform
b [Homo sapiens]
Length = 317
Score = 362 bits (930), Expect = e-100
Identities = 189/274 (68%), Positives = 212/274 (77%), Gaps = 9/274 (3%)
Query: 44 ENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQE 103
E+ +S P + G K + S G GA+DP+KKK+QRRQRTHFTSQQLQE
Sbjct: 42 ESRKEAASSKFFPRQHPGANEK--DKSQQGKNEDVGAEDPSKKKRQRRQRTHFTSQQLQE 99
Query: 104 LEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQ 163
LEATFQRNRYPDMS REEIAVWTNLTE RVRVWFKNRRAKWRKRERNQQ +LCK G+ PQ
Sbjct: 100 LEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQ 159
Query: 164 FSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSM--SPLSSQSMFSAPSSIS 221
F+GL+QPY+D+Y GYSYNNWAAK L A LSTKSF FFNSM +PLSSQSMFS P+SIS
Sbjct: 160 FNGLMQPYDDMY-PGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSIS 218
Query: 222 SMTMPSSMGPGAVPGMPNS---GLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTC 278
SM+M SSM P AV G+P S LNN+NNL+ SLNSA+ ACPY P PY VYRDTC
Sbjct: 219 SMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSLNSAVPTPACPYAPPTPPY-VYRDTC 277
Query: 279 NSSLASLRLKSKQHSSFGYGGLQGPASGLNACQY 312
NSSLASLRLK+KQHSSFGY +Q PAS L+ACQY
Sbjct: 278 NSSLASLRLKAKQHSSFGYASVQNPASNLSACQY 311
>gi|24234711 paired-like homeodomain transcription factor 2 isoform
a [Homo sapiens]
Length = 271
Score = 360 bits (925), Expect = e-100
Identities = 182/239 (76%), Positives = 201/239 (84%), Gaps = 7/239 (2%)
Query: 79 GADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFK 138
GA+DP+KKK+QRRQRTHFTSQQLQELEATFQRNRYPDMS REEIAVWTNLTE RVRVWFK
Sbjct: 29 GAEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFK 88
Query: 139 NRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKS 198
NRRAKWRKRERNQQ +LCK G+ PQF+GL+QPY+D+Y GYSYNNWAAK L A LSTKS
Sbjct: 89 NRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMY-PGYSYNNWAAKGLTSASLSTKS 147
Query: 199 FTFFNSM--SPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNS---GLNNINNLTGSSL 253
F FFNSM +PLSSQSMFS P+SISSM+M SSM P AV G+P S LNN+NNL+ SL
Sbjct: 148 FPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSSLNSLNNLNNLSSPSL 207
Query: 254 NSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQGPASGLNACQY 312
NSA+ ACPY P PY VYRDTCNSSLASLRLK+KQHSSFGY +Q PAS L+ACQY
Sbjct: 208 NSAVPTPACPYAPPTPPY-VYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQY 265
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 280 bits (717), Expect = 9e-76
Identities = 164/299 (54%), Positives = 197/299 (65%), Gaps = 22/299 (7%)
Query: 31 FHLARPADPREP-LENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQ 89
F L A+ R P L S + + +LPE G+ + + G +D + KKKQ
Sbjct: 3 FGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLKKKQ 62
Query: 90 RRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRER 149
RRQRTHFTSQQLQELEATFQRNRYPDMS REEIAVWTNLTE RVRVWFKNRRAKWRKRER
Sbjct: 63 RRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRER 122
Query: 150 NQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTF-FNSMS-- 206
+QQ +LCKG + GLV PYE+VY GYSY NW K+LAP PL+ K+F F FNS++
Sbjct: 123 SQQAELCKGSFAAPLGGLVPPYEEVY-PGYSYGNWPPKALAP-PLAAKTFPFAFNSVNVG 180
Query: 207 PLSSQSMFSAPSSISSMTMPS-SMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGA--CP 263
PL+SQ +FS PSSI++ +PS + PG VPG L + +A+S GA CP
Sbjct: 181 PLASQPVFSPPSSIAASMVPSAAAAPGTVPG--PGALQGLGGGPPGLAPAAVSSGAVSCP 238
Query: 264 YGTPA--------SPYSVYRDTCNSSLASLRLKSKQHSSFGYGGLQG--PASGLNACQY 312
Y + A SPY VYRD CNSSLASLRLK+KQH+SF Y + G PA+ L+ CQY
Sbjct: 239 YASAAAAAAAAASSPY-VYRDPCNSSLASLRLKAKQHASFSYPAVHGPPPAANLSPCQY 296
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 115 bits (289), Expect = 4e-26
Identities = 98/319 (30%), Positives = 145/319 (45%), Gaps = 58/319 (18%)
Query: 14 PEGLRPPPPPPHDMGPAFHLARPADPREP------LENSASESSDTELP---EKERGGEP 64
P+ +P P PP P +L R A P E S+ S+ ++P ++ GEP
Sbjct: 107 PQQQQPQPQPPAQ--PHLYLQRGACKTPPDGSLKLQEGSSGHSAALQVPCYAKESSLGEP 164
Query: 65 KGPEDSGAGG----------TGCGG---------------ADDPAKKKKQRRQRTHFTSQ 99
+ P DS G G G AD + K K+RR RT FTS
Sbjct: 165 ELPPDSDTVGMDSSYLSVKEAGVKGPQDRASSDLPSPLEKADSESNKGKKRRNRTTFTSY 224
Query: 100 QLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGG 159
QL+ELE FQ+ YPD+ RE++A+ T+LTE RV+VWF+NRRAKWRKRER Q+ +
Sbjct: 225 QLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQVRTH 284
Query: 160 YVPQFS----GLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFS 215
+ + + Y + + NN AA +P P + + S
Sbjct: 285 FSTAYELPLLTRAENYAQIQNPSWLGNNGAA---SPVPACVVPCDPVPACMSPHAHPPGS 341
Query: 216 APSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYR 275
SS++ S G + G ++ +L G+ +++SPG Y P
Sbjct: 342 GASSVTDFLSVSGAG-------SHVGQTHMGSLFGA---ASLSPGLNGYELNGEP----- 386
Query: 276 DTCNSSLASLRLKSKQHSS 294
D SS+A+LR+K+K+HS+
Sbjct: 387 DRKTSSIAALRMKAKEHSA 405
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 105 bits (261), Expect = 7e-23
Identities = 91/279 (32%), Positives = 134/279 (48%), Gaps = 24/279 (8%)
Query: 50 SSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQ 109
S EL E K EDS G +++ K+KQRR RT FTS QL+ELE FQ
Sbjct: 290 SPKEELLLHPEDAEGKDGEDSVCLSAG-SDSEEGLLKRKQRRYRTTFTSYQLEELERAFQ 348
Query: 110 RNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVP---QFSG 166
+ YPD+ REE+A+ +LTE RV+VWF+NRRAKWRKRE+ G P +
Sbjct: 349 KTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATH 408
Query: 167 LVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMP 226
+ PY D A+ + ++ A S A + + F + P S S+ P S + + +
Sbjct: 409 PLSPYLD--ASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPGSASL---PPSGAPLGLS 463
Query: 227 SSMG------PGAVPGMPNSGLNNINNLTGSSLNSAM-------SPGACPYGTPASPYSV 273
+ +G P + + + LT +S +A+ GA G A P +
Sbjct: 464 TFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPAVEGAVASGALADPATA 523
Query: 274 YRDTCNSSLASLRLKSKQHSS--FGYGGLQGPASGLNAC 310
D SS+A+LRLK+K+H++ L G ++G C
Sbjct: 524 AADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC 562
>gi|154813201 cartilage paired-class homeoprotein 1 [Homo sapiens]
Length = 326
Score = 104 bits (260), Expect = 9e-23
Identities = 76/232 (32%), Positives = 111/232 (47%), Gaps = 21/232 (9%)
Query: 65 KGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAV 124
KG ++ G D K+RR RT FTS QL+ELE FQ+ YPD+ +RE++A+
Sbjct: 108 KGMQEKGELDELGDKCDSNVSSSKKRRHRTTFTSLQLEELEKVFQKTHYPDVYVREQLAL 167
Query: 125 WTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNW 184
T LTE RV+VWF+NRRAKWRKRER Q+ K + + V P D Y N W
Sbjct: 168 RTELTEARVQVWFQNRRAKWRKRERYGQIQQAKSHFAATYDISVLPRTDSYPQ-IQNNLW 226
Query: 185 AAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNN 244
A + + ++ + M P + S + P S S T S G N+
Sbjct: 227 AGNASGGSVVT-------SCMLPRDTSSCMT-PYSHSPRTDSSYTGFS----------NH 268
Query: 245 INNLTGSSLNSAMSPGACPYGTPASPYSVYR--DTCNSSLASLRLKSKQHSS 294
N + LN+ + T + + +SS+A LR+K+K+H++
Sbjct: 269 QNQFSHVPLNNFFTDSLLTGATNGHAFETKPEFERRSSSIAVLRMKAKEHTA 320
>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
Length = 343
Score = 103 bits (256), Expect = 3e-22
Identities = 68/177 (38%), Positives = 95/177 (53%), Gaps = 16/177 (9%)
Query: 13 LPEGLRPPPPPPHDMGPAFHLARP---ADPREPLENSASESSDTELPEKERGGEPKGPED 69
LPE +PP D+GP L P E E ++ +S +LP RGG GP +
Sbjct: 61 LPEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSN 120
Query: 70 -SGAGGT-----------GCGGADDPAKKK-KQRRQRTHFTSQQLQELEATFQRNRYPDM 116
G+ G G + + AK K K+RR RT F++ QL+ELE FQ+ YPD+
Sbjct: 121 LQGSPGPCLASLHLPLSPGLPDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDV 180
Query: 117 SMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYED 173
RE++A+ T+LTE RV+VWF+NRRAKWRKRER ++ + + + V P D
Sbjct: 181 YAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQEGRNPFTAAYDISVLPRTD 237
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 103 bits (256), Expect = 3e-22
Identities = 93/292 (31%), Positives = 121/292 (41%), Gaps = 49/292 (16%)
Query: 15 EGLRPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGG 74
EG P PPP P + RP P+EP E S LP GE K E+
Sbjct: 79 EGSEPSPPPAPAPAPEYEAPRPYCPKEPGEARPSPG----LPVGPATGEAKLSEEE---- 130
Query: 75 TGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVR 134
KKK RR RT FT+ QL ELE F+++ YPD+ REE+A NL E RV+
Sbjct: 131 ---------QPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRVQ 181
Query: 135 VWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYA---AGYSYNNWAAKSLAP 191
VWF+NRRAKWR++E+ ++ K P S P + AG A P
Sbjct: 182 VWFQNRRAKWRRQEK-LEVSSMKLQDSPLLSFSRSPPSATLSPLGAGPGSGGGPAGGALP 240
Query: 192 APLSTKSFTFFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGS 251
+ L S F P + ++P+S P P P LN
Sbjct: 241 LESWLGPPLPGGGATALQSLPGFGPP----AQSLPASYTP---PPPPPPFLN-------- 285
Query: 252 SLNSAMSPGACPYGTPASPYSV-----------YRDTCNSSLASLRLKSKQH 292
+ + PG P P Y D NSS+A+LRLK+K+H
Sbjct: 286 --SPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAALRLKAKEH 335
Score = 29.3 bits (64), Expect = 4.7
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 2/36 (5%)
Query: 13 LPEGLRP--PPPPPHDMGPAFHLARPADPREPLENS 46
L GL+P PPPP + GP F P D +P +S
Sbjct: 289 LGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSS 324
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 101 bits (252), Expect = 8e-22
Identities = 79/232 (34%), Positives = 109/232 (46%), Gaps = 42/232 (18%)
Query: 73 GGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPR 132
G G DD ++KQRR RT FT QQL+ LEA F + YPD+ REE+A+ NLTE R
Sbjct: 22 GNHSSGDFDDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEAR 81
Query: 133 VRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPA 192
V+VWF+NRRAKWRK ER G Q G +P +V P
Sbjct: 82 VQVWFQNRRAKWRKTER---------GASDQEPGAKEPMAEV---------------TPP 117
Query: 193 PLSTKSFTFFNSMSP----LSSQSMFSAPSSISSMTMPSS-MGPGAVPG-MPNS-----G 241
P+ NS P S + A S+ P+ P +PG + N+
Sbjct: 118 PVRN-----INSPPPGDQARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQA 172
Query: 242 LNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLASLRLKSKQHS 293
L+++ +L G L S P P G P + +S+A+LR+K+++HS
Sbjct: 173 LSHVASLKGGPLCSCCVPD--PMGLSFLPTYGCQSNRTASVATLRMKAREHS 222
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 101 bits (251), Expect = 1e-21
Identities = 98/309 (31%), Positives = 139/309 (44%), Gaps = 46/309 (14%)
Query: 12 RLPEGLRPPPPPPHDMGPAFHLARPAD--PREPLENSASESSDTELPEKERGGEPKGPED 69
RL G P P D+ P A P E + S + + K+ +P GP+
Sbjct: 30 RLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQP-GPQ- 87
Query: 70 SGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLT 129
GG A ++KQ+R RT FT QL ELE +F + YPD+ MREE+A+ LT
Sbjct: 88 ---GGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLT 144
Query: 130 EPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNN------ 183
E RV+VWF+NRRAKW+KR++ + G +P GL Q AA + +
Sbjct: 145 ESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPT-PGLPQFPSAAAAAAAAMGDSLCSFH 203
Query: 184 -----WAAKSL---APAPLSTKSFTFFNSMSPLSSQSMFSAPSSIS---SMTMPSSMGPG 232
WAA ++ + PL LS S+ + P S S ++ S G G
Sbjct: 204 ANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAG 263
Query: 233 --------AVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLAS 284
A PGM + L +N++G SP C +P S V+R T S+AS
Sbjct: 264 LQSHLYQPAFPGMVPASLPGPSNVSG-------SPQLC--SSPDSS-DVWRGT---SIAS 310
Query: 285 LRLKSKQHS 293
LR K+ +H+
Sbjct: 311 LRRKALEHT 319
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 101 bits (251), Expect = 1e-21
Identities = 98/309 (31%), Positives = 139/309 (44%), Gaps = 46/309 (14%)
Query: 12 RLPEGLRPPPPPPHDMGPAFHLARPAD--PREPLENSASESSDTELPEKERGGEPKGPED 69
RL G P P D+ P A P E + S + + K+ +P GP+
Sbjct: 30 RLGVGGSDPGGHPGDLAPNSDPVEGATLLPGEDITTVGSTPASLAVSAKDPDKQP-GPQ- 87
Query: 70 SGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLT 129
GG A ++KQ+R RT FT QL ELE +F + YPD+ MREE+A+ LT
Sbjct: 88 ---GGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLT 144
Query: 130 EPRVRVWFKNRRAKWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNN------ 183
E RV+VWF+NRRAKW+KR++ + G +P GL Q AA + +
Sbjct: 145 ESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPT-PGLPQFPSAAAAAAAAMGDSLCSFH 203
Query: 184 -----WAAKSL---APAPLSTKSFTFFNSMSPLSSQSMFSAPSSIS---SMTMPSSMGPG 232
WAA ++ + PL LS S+ + P S S ++ S G G
Sbjct: 204 ANDTRWAAAAMPGVSQLPLPPALGRQQAMAQSLSQCSLAAGPPPNSMGLSNSLAGSNGAG 263
Query: 233 --------AVPGMPNSGLNNINNLTGSSLNSAMSPGACPYGTPASPYSVYRDTCNSSLAS 284
A PGM + L +N++G SP C +P S V+R T S+AS
Sbjct: 264 LQSHLYQPAFPGMVPASLPGPSNVSG-------SPQLC--SSPDSS-DVWRGT---SIAS 310
Query: 285 LRLKSKQHS 293
LR K+ +H+
Sbjct: 311 LRRKALEHT 319
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 100 bits (250), Expect = 1e-21
Identities = 68/173 (39%), Positives = 84/173 (48%), Gaps = 33/173 (19%)
Query: 1 MDAFKGGMSLERLPEGLRPPPPPPHDMGPA-----------FHL-------------ARP 36
MD+ +L++ G PPPPPP +GP HL ARP
Sbjct: 1 MDSAAAAFALDKPALGPGPPPPPPA-LGPGDCAQARKNFSVSHLLDLEEVAAAGRLAARP 59
Query: 37 ADPREPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHF 96
E E +A E P G P+D G G A +KKKQRR RT F
Sbjct: 60 GARAEAREGAARE------PSGGSSGSEAAPQDGECPSPGRGSA--AKRKKKQRRNRTTF 111
Query: 97 TSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRER 149
S QLQ LE F+R YPD +REE+A NL+E RV+VWF+NRRAK+R+ ER
Sbjct: 112 NSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNER 164
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 99.0 bits (245), Expect = 5e-21
Identities = 79/246 (32%), Positives = 116/246 (47%), Gaps = 27/246 (10%)
Query: 49 ESSDTELPEKERGGEPKGPE-------DSGAG---GTGCGGADDPAKKKKQRRQRTHFTS 98
+ + E +KE GE K D G G+ D K+KQRR RT FT+
Sbjct: 167 KEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTA 226
Query: 99 QQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----D 154
+QL+ELE F+R YPD+ REE+A T LTE RV+VWF NRRA+WRK+ QL
Sbjct: 227 EQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNH 286
Query: 155 LCKGGYVPQFSGLVQPY---EDVYAAGYSYNNWAAKSLAPAPLSTKSF---TFFNSMSPL 208
L GG+ P + PY + Y + + P PL + + +
Sbjct: 287 LLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 346
Query: 209 SSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINN-LTGSSLNSAMSPGACPYGTP 267
+ S + A S SS + S M P A P++ +N ++N L+ ++ +P A P P
Sbjct: 347 DTSSAYGARHSFSSYS-DSFMNPAA----PSNHMNPVSNGLSPQVMSILGNPSAVP-PQP 400
Query: 268 ASPYSV 273
+ +S+
Sbjct: 401 QADFSI 406
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 99.0 bits (245), Expect = 5e-21
Identities = 79/246 (32%), Positives = 116/246 (47%), Gaps = 27/246 (10%)
Query: 49 ESSDTELPEKERGGEPKGPE-------DSGAG---GTGCGGADDPAKKKKQRRQRTHFTS 98
+ + E +KE GE K D G G+ D K+KQRR RT FT+
Sbjct: 165 KEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTA 224
Query: 99 QQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----D 154
+QL+ELE F+R YPD+ REE+A T LTE RV+VWF NRRA+WRK+ QL
Sbjct: 225 EQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNH 284
Query: 155 LCKGGYVPQFSGLVQPY---EDVYAAGYSYNNWAAKSLAPAPLSTKSF---TFFNSMSPL 208
L GG+ P + PY + Y + + P PL + + +
Sbjct: 285 LLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 344
Query: 209 SSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINN-LTGSSLNSAMSPGACPYGTP 267
+ S + A S SS + S M P A P++ +N ++N L+ ++ +P A P P
Sbjct: 345 DTSSAYGARHSFSSYS-DSFMNPAA----PSNHMNPVSNGLSPQVMSILGNPSAVP-PQP 398
Query: 268 ASPYSV 273
+ +S+
Sbjct: 399 QADFSI 404
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 99.0 bits (245), Expect = 5e-21
Identities = 79/246 (32%), Positives = 116/246 (47%), Gaps = 27/246 (10%)
Query: 49 ESSDTELPEKERGGEPKGPE-------DSGAG---GTGCGGADDPAKKKKQRRQRTHFTS 98
+ + E +KE GE K D G G+ D K+KQRR RT FT+
Sbjct: 167 KEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFTA 226
Query: 99 QQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----D 154
+QL+ELE F+R YPD+ REE+A T LTE RV+VWF NRRA+WRK+ QL
Sbjct: 227 EQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQLAAFNH 286
Query: 155 LCKGGYVPQFSGLVQPY---EDVYAAGYSYNNWAAKSLAPAPLSTKSF---TFFNSMSPL 208
L GG+ P + PY + Y + + P PL + + +
Sbjct: 287 LLPGGFPPTGMPTLPPYQLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAA 346
Query: 209 SSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINN-LTGSSLNSAMSPGACPYGTP 267
+ S + A S SS + S M P A P++ +N ++N L+ ++ +P A P P
Sbjct: 347 DTSSAYGARHSFSSYS-DSFMNPAA----PSNHMNPVSNGLSPQVMSILGNPSAVP-PQP 400
Query: 268 ASPYSV 273
+ +S+
Sbjct: 401 QADFSI 406
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 96.7 bits (239), Expect = 2e-20
Identities = 77/224 (34%), Positives = 103/224 (45%), Gaps = 22/224 (9%)
Query: 41 EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ 100
E E A S D L ER P+ E G+ D K+KQRR RT FT++Q
Sbjct: 177 EESEKKAKHSIDGIL--SERASAPQSDE-----GSDIDSEPDLPLKRKQRRSRTTFTAEQ 229
Query: 101 LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----DLC 156
L+ELE F+R YPD+ REE+A LTE RV+VWF NRRA+WRK+ QL L
Sbjct: 230 LEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLI 289
Query: 157 KGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSA 216
GG+ P + Y+ + SY + P ST S + ++ S
Sbjct: 290 PGGFPPTAMPTLPTYQ---LSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN 346
Query: 217 PSSISSMTMP------SSMGPGAVPGMPNSGLNNINNLTGSSLN 254
P S S+ +P SS VP P+ N +N G+ L+
Sbjct: 347 PDSSSAYCLPSTRHGFSSYTDSFVP--PSGPSNPMNPTIGNGLS 388
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 96.7 bits (239), Expect = 2e-20
Identities = 77/224 (34%), Positives = 103/224 (45%), Gaps = 22/224 (9%)
Query: 41 EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ 100
E E A S D L ER P+ E G+ D K+KQRR RT FT++Q
Sbjct: 178 EESEKKAKHSIDGIL--SERASAPQSDE-----GSDIDSEPDLPLKRKQRRSRTTFTAEQ 230
Query: 101 LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----DLC 156
L+ELE F+R YPD+ REE+A LTE RV+VWF NRRA+WRK+ QL L
Sbjct: 231 LEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLI 290
Query: 157 KGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSA 216
GG+ P + Y+ + SY + P ST S + ++ S
Sbjct: 291 PGGFPPTAMPTLPTYQ---LSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN 347
Query: 217 PSSISSMTMP------SSMGPGAVPGMPNSGLNNINNLTGSSLN 254
P S S+ +P SS VP P+ N +N G+ L+
Sbjct: 348 PDSSSAYCLPSTRHGFSSYTDSFVP--PSGPSNPMNPTIGNGLS 389
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 96.7 bits (239), Expect = 2e-20
Identities = 77/224 (34%), Positives = 103/224 (45%), Gaps = 22/224 (9%)
Query: 41 EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ 100
E E A S D L ER P+ E G+ D K+KQRR RT FT++Q
Sbjct: 178 EESEKKAKHSIDGIL--SERASAPQSDE-----GSDIDSEPDLPLKRKQRRSRTTFTAEQ 230
Query: 101 LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----DLC 156
L+ELE F+R YPD+ REE+A LTE RV+VWF NRRA+WRK+ QL L
Sbjct: 231 LEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLI 290
Query: 157 KGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSA 216
GG+ P + Y+ + SY + P ST S + ++ S
Sbjct: 291 PGGFPPTAMPTLPTYQ---LSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN 347
Query: 217 PSSISSMTMP------SSMGPGAVPGMPNSGLNNINNLTGSSLN 254
P S S+ +P SS VP P+ N +N G+ L+
Sbjct: 348 PDSSSAYCLPSTRHGFSSYTDSFVP--PSGPSNPMNPTIGNGLS 389
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 96.7 bits (239), Expect = 2e-20
Identities = 77/224 (34%), Positives = 103/224 (45%), Gaps = 22/224 (9%)
Query: 41 EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ 100
E E A S D L ER P+ E G+ D K+KQRR RT FT++Q
Sbjct: 178 EESEKKAKHSIDGIL--SERASAPQSDE-----GSDIDSEPDLPLKRKQRRSRTTFTAEQ 230
Query: 101 LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----DLC 156
L+ELE F+R YPD+ REE+A LTE RV+VWF NRRA+WRK+ QL L
Sbjct: 231 LEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLI 290
Query: 157 KGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSA 216
GG+ P + Y+ + SY + P ST S + ++ S
Sbjct: 291 PGGFPPTAMPTLPTYQ---LSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN 347
Query: 217 PSSISSMTMP------SSMGPGAVPGMPNSGLNNINNLTGSSLN 254
P S S+ +P SS VP P+ N +N G+ L+
Sbjct: 348 PDSSSAYCLPSTRHGFSSYTDSFVP--PSGPSNPMNPTIGNGLS 389
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 96.7 bits (239), Expect = 2e-20
Identities = 77/224 (34%), Positives = 103/224 (45%), Gaps = 22/224 (9%)
Query: 41 EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ 100
E E A S D L ER P+ E G+ D K+KQRR RT FT++Q
Sbjct: 178 EESEKKAKHSIDGIL--SERASAPQSDE-----GSDIDSEPDLPLKRKQRRSRTTFTAEQ 230
Query: 101 LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----DLC 156
L+ELE F+R YPD+ REE+A LTE RV+VWF NRRA+WRK+ QL L
Sbjct: 231 LEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLI 290
Query: 157 KGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSA 216
GG+ P + Y+ + SY + P ST S + ++ S
Sbjct: 291 PGGFPPTAMPTLPTYQ---LSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN 347
Query: 217 PSSISSMTMP------SSMGPGAVPGMPNSGLNNINNLTGSSLN 254
P S S+ +P SS VP P+ N +N G+ L+
Sbjct: 348 PDSSSAYCLPSTRHGFSSYTDSFVP--PSGPSNPMNPTIGNGLS 389
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 96.7 bits (239), Expect = 2e-20
Identities = 77/224 (34%), Positives = 103/224 (45%), Gaps = 22/224 (9%)
Query: 41 EPLENSASESSDTELPEKERGGEPKGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQ 100
E E A S D L ER P+ E G+ D K+KQRR RT FT++Q
Sbjct: 178 EESEKKAKHSIDGIL--SERASAPQSDE-----GSDIDSEPDLPLKRKQRRSRTTFTAEQ 230
Query: 101 LQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKWRKRERNQQL----DLC 156
L+ELE F+R YPD+ REE+A LTE RV+VWF NRRA+WRK+ QL L
Sbjct: 231 LEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLI 290
Query: 157 KGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFFNSMSPLSSQSMFSA 216
GG+ P + Y+ + SY + P ST S + ++ S
Sbjct: 291 PGGFPPTAMPTLPTYQ---LSETSYQPTSIPQAVSDPSSTVHRPQPLPPSTVHQSTIPSN 347
Query: 217 PSSISSMTMP------SSMGPGAVPGMPNSGLNNINNLTGSSLN 254
P S S+ +P SS VP P+ N +N G+ L+
Sbjct: 348 PDSSSAYCLPSTRHGFSSYTDSFVP--PSGPSNPMNPTIGNGLS 389
>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
Length = 354
Score = 93.2 bits (230), Expect = 3e-19
Identities = 62/183 (33%), Positives = 93/183 (50%), Gaps = 28/183 (15%)
Query: 83 PAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRA 142
PA +KQRR+RT FT QL LEA F + RYPD+ MREE+A+ NL E RV+VWFKNRRA
Sbjct: 32 PATPRKQRRERTTFTRSQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
Query: 143 KWRKRERNQQLDLCKGGYVPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTFF 202
K R++++ + + + A K +P S+ S +
Sbjct: 92 KCRQQQQ--------------------------SGSGTKSRPAKKKSSPVRESSGSESSG 125
Query: 203 NSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNS--AMSPG 260
P S S S+ S+ SS P++ + G P + ++++ SS+ S ++SPG
Sbjct: 126 QFTPPAVSSSASSSSSASSSSANPAAAAAAGLGGNPVAAASSLSTPAASSIWSPASISPG 185
Query: 261 ACP 263
+ P
Sbjct: 186 SAP 188
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 92.0 bits (227), Expect = 6e-19
Identities = 88/274 (32%), Positives = 121/274 (44%), Gaps = 49/274 (17%)
Query: 26 DMGPAFHLARPADPREPLENSASESSDTELPE-KERGGEPKGPEDSGAGGTGCGGADDPA 84
DMG A P PR +E S PE K+R + KG ED G
Sbjct: 98 DMGAAERSREPGSPR------LTEVS----PELKDRKEDAKGMEDEGQ------------ 135
Query: 85 KKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAKW 144
K KQRR RT+FT +QL ELE F YPD MREE++ L+E RV+VWF+NRRAK
Sbjct: 136 TKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 195
Query: 145 RKRERNQQLDLCKG---GYVPQFSGL-VQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFT 200
RK+E L KG G QF V PY +V A + + ++ P ++
Sbjct: 196 RKQEN----QLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQDSHCNVTPLSFQVQAQL 251
Query: 201 FFNSMSPLSSQSMFSAPSSISSMTMPSSMGPGAVPGMPNSGLNNINNLTGSSLNSAMSPG 260
+S + + ++ + P M P G+P + L S ++A
Sbjct: 252 QLDSAVAHAHHHLHPHLAAHA----PYMMFPAPPFGLP------LATLAADSASAASVVA 301
Query: 261 ACPYGTPASPYSVYRDTCNSSLASLRLKSKQHSS 294
A S NSS+A LRLK+K+H++
Sbjct: 302 AAAAAKTTSK--------NSSIADLRLKAKKHAA 327
>gi|22218349 diencephalon/mesencephalon homeobox 1 isoform b [Homo
sapiens]
Length = 382
Score = 91.7 bits (226), Expect = 8e-19
Identities = 42/69 (60%), Positives = 56/69 (81%)
Query: 84 AKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAK 143
++ +KQRR RT FT+QQL+ LE TFQ+ YPD+ MRE +A+ TNL E RV+VWFKNRRAK
Sbjct: 66 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 125
Query: 144 WRKRERNQQ 152
+RK++R+ Q
Sbjct: 126 FRKKQRSLQ 134
Score = 28.9 bits (63), Expect = 6.2
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 12/66 (18%)
Query: 18 RPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKE---RGG--EPKGPEDSGA 72
+PP P D HL+ E SASES+ + P++E R G +PK + GA
Sbjct: 166 QPPRLPGSDPPAELHLSLS-------EQSASESAPEDQPDREEDPRAGAEDPKAEKSPGA 218
Query: 73 GGTGCG 78
G G
Sbjct: 219 DSKGLG 224
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 91.7 bits (226), Expect = 8e-19
Identities = 42/69 (60%), Positives = 56/69 (81%)
Query: 84 AKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAK 143
++ +KQRR RT FT+QQL+ LE TFQ+ YPD+ MRE +A+ TNL E RV+VWFKNRRAK
Sbjct: 61 SQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAK 120
Query: 144 WRKRERNQQ 152
+RK++R+ Q
Sbjct: 121 FRKKQRSLQ 129
Score = 28.9 bits (63), Expect = 6.2
Identities = 22/66 (33%), Positives = 30/66 (45%), Gaps = 12/66 (18%)
Query: 18 RPPPPPPHDMGPAFHLARPADPREPLENSASESSDTELPEKE---RGG--EPKGPEDSGA 72
+PP P D HL+ E SASES+ + P++E R G +PK + GA
Sbjct: 161 QPPRLPGSDPPAELHLSLS-------EQSASESAPEDQPDREEDPRAGAEDPKAEKSPGA 213
Query: 73 GGTGCG 78
G G
Sbjct: 214 DSKGLG 219
>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
Length = 289
Score = 91.3 bits (225), Expect = 1e-18
Identities = 63/148 (42%), Positives = 83/148 (56%), Gaps = 16/148 (10%)
Query: 83 PAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRA 142
PA +KQRR+RT FT QL LEA F + RYPD+ MREE+A+ NL E RV+VWFKNRRA
Sbjct: 32 PATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRA 91
Query: 143 KWRKRERNQQLDLCKGGY--VPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFT 200
K R++++ QQ GG V P +V S + + P P ST T
Sbjct: 92 KCRQQQQQQQ----NGGQNKVRPAKKKTSPAREV-----SSESGTSGQFTP-PSSTSVPT 141
Query: 201 FFNSMSPLSSQSMFSAPSSISSMTMPSS 228
+S +P+S S P+SIS ++ P S
Sbjct: 142 IASSSAPVSIWS----PASISPLSDPLS 165
>gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
Length = 297
Score = 88.6 bits (218), Expect = 7e-18
Identities = 62/147 (42%), Positives = 82/147 (55%), Gaps = 16/147 (10%)
Query: 84 AKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAVWTNLTEPRVRVWFKNRRAK 143
A +KQRR+RT FT QL LEA F + RYPD+ MREE+A+ NL E RV+VWFKNRRAK
Sbjct: 41 ATPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAK 100
Query: 144 WRKRERNQQLDLCKGGY--VPQFSGLVQPYEDVYAAGYSYNNWAAKSLAPAPLSTKSFTF 201
R++++ QQ GG V P +V S + + P P ST T
Sbjct: 101 CRQQQQQQQ----NGGQNKVRPAKKKTSPAREV-----SSESGTSGQFTP-PSSTSVPTI 150
Query: 202 FNSMSPLSSQSMFSAPSSISSMTMPSS 228
+S +P+S S P+SIS ++ P S
Sbjct: 151 ASSSAPVSIWS----PASISPLSDPLS 173
>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
Length = 184
Score = 87.8 bits (216), Expect = 1e-17
Identities = 45/85 (52%), Positives = 58/85 (68%), Gaps = 4/85 (4%)
Query: 65 KGPEDSGAGGTGCGGADDPAKKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSMREEIAV 124
+GP G GG G G + A KKK RR RT FT+ QL +LE F+ + YPD+ REE+A
Sbjct: 7 EGPATEG-GGLGPG---EEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAA 62
Query: 125 WTNLTEPRVRVWFKNRRAKWRKRER 149
+L E RV+VWF+NRRAKWR++ER
Sbjct: 63 KVHLPEVRVQVWFQNRRAKWRRQER 87
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,830,717
Number of Sequences: 37866
Number of extensions: 892196
Number of successful extensions: 8662
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 395
Number of HSP's successfully gapped in prelim test: 318
Number of HSP's that attempted gapping in prelim test: 7050
Number of HSP's gapped (non-prelim): 1729
length of query: 314
length of database: 18,247,518
effective HSP length: 102
effective length of query: 212
effective length of database: 14,385,186
effective search space: 3049659432
effective search space used: 3049659432
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.