Guide to the Human Genome
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Search of human proteins with 15208665

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
sapiens]
         (442 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...   905   0.0  
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...   905   0.0  
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...   905   0.0  
gi|15208669 tripartite motif protein TRIM14 isoform beta [Homo s...   469   e-132
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   125   6e-29
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   125   8e-29
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    119   7e-27
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   112   9e-25
gi|15208660 tripartite motif protein 21 [Homo sapiens]                111   1e-24
gi|5730009 ret finger protein [Homo sapiens]                          110   3e-24
gi|217035095 tripartite motif-containing 62 [Homo sapiens]            107   2e-23
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             104   2e-22
gi|38679905 tripartite motif-containing 65 [Homo sapiens]             103   2e-22
gi|68160937 tripartite motif-containing 25 [Homo sapiens]             103   3e-22
gi|30023818 tripartite motif protein 50A [Homo sapiens]               102   5e-22
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            102   7e-22
gi|48255913 tripartite motif-containing 16 [Homo sapiens]             101   1e-21
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]       99   8e-21
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]       99   8e-21
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...    99   8e-21
gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]     96   8e-20
gi|154354992 B-box and SPRY domain containing [Homo sapiens]           96   8e-20
gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]     96   8e-20
gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]     96   8e-20
gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]     96   8e-20
gi|4557743 Mediterranean fever protein [Homo sapiens]                  93   4e-19
gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo...    93   6e-19
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ...    93   6e-19
gi|5454014 tripartite motif-containing 38 [Homo sapiens]               92   9e-19
gi|27734883 tripartite motif family-like 2 [Homo sapiens]              92   1e-18

>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  905 bits (2340), Expect = 0.0
 Identities = 442/442 (100%), Positives = 442/442 (100%)

Query: 1   MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 60
           MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL
Sbjct: 1   MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 60

Query: 61  ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 120
           ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL
Sbjct: 61  ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 120

Query: 121 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 180
           LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA
Sbjct: 121 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 180

Query: 181 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 240
           YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS
Sbjct: 181 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 240

Query: 241 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 300
           DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV
Sbjct: 241 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 300

Query: 301 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 360
           PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ
Sbjct: 301 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 360

Query: 361 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 420
           SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT
Sbjct: 361 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 420

Query: 421 FQEPLYPALRLWEGAISIPRLP 442
           FQEPLYPALRLWEGAISIPRLP
Sbjct: 421 FQEPLYPALRLWEGAISIPRLP 442


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  905 bits (2340), Expect = 0.0
 Identities = 442/442 (100%), Positives = 442/442 (100%)

Query: 1   MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 60
           MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL
Sbjct: 1   MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 60

Query: 61  ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 120
           ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL
Sbjct: 61  ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 120

Query: 121 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 180
           LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA
Sbjct: 121 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 180

Query: 181 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 240
           YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS
Sbjct: 181 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 240

Query: 241 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 300
           DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV
Sbjct: 241 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 300

Query: 301 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 360
           PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ
Sbjct: 301 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 360

Query: 361 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 420
           SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT
Sbjct: 361 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 420

Query: 421 FQEPLYPALRLWEGAISIPRLP 442
           FQEPLYPALRLWEGAISIPRLP
Sbjct: 421 FQEPLYPALRLWEGAISIPRLP 442


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  905 bits (2340), Expect = 0.0
 Identities = 442/442 (100%), Positives = 442/442 (100%)

Query: 1   MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 60
           MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL
Sbjct: 1   MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 60

Query: 61  ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 120
           ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL
Sbjct: 61  ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 120

Query: 121 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 180
           LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA
Sbjct: 121 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 180

Query: 181 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 240
           YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS
Sbjct: 181 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLS 240

Query: 241 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 300
           DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV
Sbjct: 241 DPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPV 300

Query: 301 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 360
           PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ
Sbjct: 301 PVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQ 360

Query: 361 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 420
           SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT
Sbjct: 361 SWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRAT 420

Query: 421 FQEPLYPALRLWEGAISIPRLP 442
           FQEPLYPALRLWEGAISIPRLP
Sbjct: 421 FQEPLYPALRLWEGAISIPRLP 442


>gi|15208669 tripartite motif protein TRIM14 isoform beta [Homo
           sapiens]
          Length = 253

 Score =  469 bits (1206), Expect = e-132
 Identities = 231/231 (100%), Positives = 231/231 (100%)

Query: 1   MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 60
           MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL
Sbjct: 1   MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGL 60

Query: 61  ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 120
           ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL
Sbjct: 61  ALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRL 120

Query: 121 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 180
           LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA
Sbjct: 121 LLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA 180

Query: 181 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRL 231
           YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRL
Sbjct: 181 YTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRL 231


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  125 bits (315), Expect = 6e-29
 Identities = 121/412 (29%), Positives = 185/412 (44%), Gaps = 63/412 (15%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           CP+H + ++ LFC   +  VC +C +   HR H V    +A    ++  Q+CL+ L    
Sbjct: 107 CPQHHEALS-LFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPL---- 161

Query: 84  QQHIDNITQIEDATEK----LKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQL 139
           +Q +  IT+ + + EK    LK   ES +  +  +F EL   LDEE+ +    +++  Q 
Sbjct: 162 EQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQD 221

Query: 140 TLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCH 199
            LQ  RE A    ++                     +R  A+ A E E +   S      
Sbjct: 222 ILQRLRENAAHLGDK---------------------RRDLAHLAAEVEGKCLQS------ 254

Query: 200 PVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKE--SINCQLSDPSSTKPGTLLKTSPSP 257
                FE +K         V+STL+    ++  E  S++ +L    S  P          
Sbjct: 255 ----GFEMLKD--------VKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFAL---- 298

Query: 258 ERSLLLKYARTPTLDPDTMHARLRLSADRLTVRC--GLLGSLGPVPVLRFDALWQVLARD 315
            R +L +     TLDP+T H  L LS DR +V+     L  L   P  RF     VLA +
Sbjct: 299 -RKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTP-RRFTFYPCVLATE 356

Query: 316 CFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFH 375
            F +GRHYWEV+V +    W VG    S+ R+G             W ++ ++ + +A  
Sbjct: 357 GFTSGRHYWEVEVGDK-THWAVGVCRDSVSRKGELTPLP---ETGYWRVRLWNGDKYAAT 412

Query: 376 DGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYP 427
               + L  +    R+G+FLDYEAG L+FY+VT   SH++TF  TF E L+P
Sbjct: 413 TTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVT-DRSHIYTFTDTFTEKLWP 463


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  125 bits (314), Expect = 8e-29
 Identities = 117/412 (28%), Positives = 187/412 (45%), Gaps = 33/412 (8%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           CP+H + ++ LFC   +  VC +C +   HR H V    +A    ++  Q+CL+ L    
Sbjct: 107 CPQHHEALS-LFCYEDQEAVCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPL---- 161

Query: 84  QQHIDNITQIEDATEK----LKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQL 139
           +Q +  IT+ + + EK    LK   ES +  +  +F EL   LDEE+ +    +++  Q 
Sbjct: 162 EQKLQEITRCKSSEEKKPGELKRLVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQD 221

Query: 140 TLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCH 199
            LQ  RE A    ++   +  L+  V     +          +  E+ + ++   G L  
Sbjct: 222 ILQRLRENAAHLGDKRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFG-GSLST 280

Query: 200 PVPLSFEPVKSFFKGL--VEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSP 257
             P   + +    K +   E V++   T + I L+++         S  P          
Sbjct: 281 ICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEKNF--------SNFPRQYFAL---- 328

Query: 258 ERSLLLKYARTPTLDPDTMHARLRLSADRLTVRC--GLLGSLGPVPVLRFDALWQVLARD 315
            R +L +     TLDP+T H  L LS DR +V+     L  L   P  RF     VLA +
Sbjct: 329 -RKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTP-RRFTFYPCVLATE 386

Query: 316 CFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFH 375
            F +GRHYWEV+V +    W VG    S+ R+G             W ++ ++ + +A  
Sbjct: 387 GFTSGRHYWEVEVGDK-THWAVGVCRDSVSRKGELTPLP---ETGYWRVRLWNGDKYAAT 442

Query: 376 DGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYP 427
               + L  +    R+G+FLDYEAG L+FY+VT   SH++TF  TF E L+P
Sbjct: 443 TTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVT-DRSHIYTFTDTFTEKLWP 493


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  119 bits (297), Expect = 7e-27
 Identities = 118/423 (27%), Positives = 188/423 (44%), Gaps = 54/423 (12%)

Query: 23  RCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIK 82
           RC +HG+   +L+C+   R +C +C     HR H V    EA    ++L +  L+ L  +
Sbjct: 129 RCGQHGEPF-KLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKE 187

Query: 83  KQQ-HIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTL 141
            +   +   T+ +++ E LK  A   +  +  +F  LR  L E+E    + + +  +L+ 
Sbjct: 188 LEDCEVFRSTEKKESKELLKQMAAEQEK-VGAEFQALRAFLVEQEG---RLLGRLEELSR 243

Query: 142 QVYREQADSCRE---QLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELC 198
           +V ++Q ++  +   ++  ++ LS+++   +Q+PD +  LQ + +T             C
Sbjct: 244 EVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPD-LDFLQEFKSTLSR----------C 292

Query: 199 HPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPE 258
             VP                      T +   +K  +   +S  +    G L K      
Sbjct: 293 SNVP------------------GPKPTTVSSEMKNKV-WNVSLKTFVLKGMLKKFKEDLR 333

Query: 259 RSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFA 318
             L  +     TLDPDT + RL LS D   VR G      P    RFD   +VLA   F+
Sbjct: 334 GELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFS 393

Query: 319 TGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQ 378
           +GRH+WEV+V     GW  G A  S+RR+G +           W L+    +YWA    +
Sbjct: 394 SGRHHWEVEVGSKD-GWAFGVARESVRRKGLTPFTP---EEGVWALQLNGGQYWAVTSPE 449

Query: 379 RSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA---------L 429
           RS L     L R+ V LD E G ++FY V   M HL+TFR  FQE ++P          L
Sbjct: 450 RSPL-SCGHLSRVRVALDLEVGAVSFYAVE-DMRHLYTFRVNFQERVFPLFSVCSTGTYL 507

Query: 430 RLW 432
           R+W
Sbjct: 508 RIW 510


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  112 bits (279), Expect = 9e-25
 Identities = 131/461 (28%), Positives = 185/461 (40%), Gaps = 72/461 (15%)

Query: 10  TPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQ 69
           TPGR   V   G  CP+H + + +LFC      +C +C    +H+ H V + LE      
Sbjct: 214 TPGRGSRVTDQGI-CPKHQEAL-KLFCEVDEEAICVVCRESRSHKQHSV-VPLE------ 264

Query: 70  KLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALA 129
               E +++   K Q H++ + +  +A +K+KA  E   T LK +      +  E  A+A
Sbjct: 265 ----EVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRVTELKSQ------MKSELAAVA 314

Query: 130 KKFIDKNTQLTLQVYREQADSCREQLDIMN-DLSNRVWSISQEPDPVQRLQAYTATEQEM 188
            +F     +LT  +  EQA   R   ++    L     + S+  +   +L    A  QE 
Sbjct: 315 SEF----GRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQLSRLLAEAQER 370

Query: 189 QQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPG 248
            QQ  L  L        + +K  F       E  LQ P    +     CQ          
Sbjct: 371 SQQGGLRLL--------QDIKETFN---RCEEVQLQPP---EVWSPDPCQPHSHDFLTDA 416

Query: 249 TLLKTSPSPERSLLLKYARTP-TLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDA 307
            + K S      +  + AR   TLDPDT H  L LS DR  VR             RF A
Sbjct: 417 IVRKMS-----RMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSA 471

Query: 308 LWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASL----------------------- 344
              VL    F +GRHYWEV+V     GW VGAA  S                        
Sbjct: 472 DCCVLGAQGFRSGRHYWEVEV-GGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRH 530

Query: 345 --RRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVL 402
             RRR      +    R+ WC+      Y A    +++ L P +   R GV+LDYEAG L
Sbjct: 531 HHRRRRLHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRL 590

Query: 403 AFYDVTGGMSHLHTFRATF-QEPLYPALRLWEGAISIPRLP 442
            FY+    ++H+HTF A F  E ++P  R+      I   P
Sbjct: 591 GFYNAE-TLAHVHTFSAAFLGERVFPFFRVLSKGTRIKLCP 630


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  111 bits (277), Expect = 1e-24
 Identities = 113/410 (27%), Positives = 178/410 (43%), Gaps = 57/410 (13%)

Query: 21  GWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLA 80
           G RC  HG+R+  LFC +  + +C +C     HR H +    EAA   Q+  Q  L +L 
Sbjct: 89  GERCAVHGERL-HLFCEKDGKALCWVCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGEL- 146

Query: 81  IKKQQHIDNITQIEDATEKL--KANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQ 138
            +++Q +    ++E A ++   K   E+ K+ +  +F + +  L EEE    + ++K+  
Sbjct: 147 -RRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQLQELEKDE- 204

Query: 139 LTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELC 198
                        REQL I+ +         +E    Q+ QA      E+ ++      C
Sbjct: 205 -------------REQLRILGE---------KEAKLAQQSQALQELISELDRR------C 236

Query: 199 HPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPE 258
           H   L           L E +         I L+ S +  L D   T P           
Sbjct: 237 HSSALEL---------LQEVI---------IVLERSESWNLKDLDITSPELRSVCHVPGL 278

Query: 259 RSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFA 318
           + +L   A   TLDPDT +  L LS DR  VR G      P    RFD+   VL    F 
Sbjct: 279 KKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFH 338

Query: 319 TGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQ 378
           +G+HYWEVDV    A W +G    S+RR+G      L      W +  ++ + +      
Sbjct: 339 SGKHYWEVDVTGKEA-WDLGVCRDSVRRKGHFL---LSSKSGFWTIWLWNKQKYEAGTYP 394

Query: 379 RSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTF-RATFQEPLYP 427
           ++ L  +    ++G+FLDYEAG+++FY++T   S +++F    F  PL P
Sbjct: 395 QTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRP 444


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  110 bits (274), Expect = 3e-24
 Identities = 123/417 (29%), Positives = 181/417 (43%), Gaps = 45/417 (10%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           C +H + + +L+C   +  +C +C     HRGH V L LE AV   K      +Q+    
Sbjct: 96  CEKHREPL-KLYCEEDQMPICVVCDRSREHRGHSV-LPLEEAVEGFK------EQI---- 143

Query: 84  QQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQV 143
           Q  +D++ +++D  ++ +A  E ++  L      L L   E E +  +F      L    
Sbjct: 144 QNQLDHLKRVKDLKKRRRAQGEQARAEL------LSLTQMEREKIVWEFEQLYHSLKEHE 197

Query: 144 YREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPL 203
           YR  A      L I N ++    +I+Q    +  L +  A  +E QQQ +  EL   +  
Sbjct: 198 YRLLARLEELDLAIYNSING---AITQFSCNISHLSSLIAQLEEKQQQPTR-ELLQDIGD 253

Query: 204 SFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQ--LSDPSSTKPGTLLKTSPSPERSL 261
           +    +         +     TP D++ K  I  Q  L    S K  T    S   +   
Sbjct: 254 TLSRAERI------RIPEPWITPPDLQEKIHIFAQKCLFLTESLKQFTEKMQSDMEKIQE 307

Query: 262 LLK---YARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFA 318
           L +   Y+   TLDPDT +  L LS +   VR   L    P    RF+    VL   CF 
Sbjct: 308 LREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFI 367

Query: 319 TGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKR-YDLEYWAFHDG 377
            GRHYWEV+V +  A W +G    S+ R+G   +A        W +   Y  EYWA    
Sbjct: 368 AGRHYWEVEVGDK-AKWTIGVCEDSVCRKGGVTSAP---QNGFWAVSLWYGKEYWAL-TS 422

Query: 378 QRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTF---RATFQEPLYPALRL 431
             + L  R  L R+G+FLDY+AG ++FY+VT      HTF    ATF  P+ P   L
Sbjct: 423 PMTALPLRTPLQRVGIFLDYDAGEVSFYNVT---ERCHTFTFSHATFCGPVRPYFSL 476


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score =  107 bits (268), Expect = 2e-23
 Identities = 115/409 (28%), Positives = 180/409 (44%), Gaps = 67/409 (16%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           C  H D+V +LFC   R  +C  C     H  H V    +A   +Q+  ++ L+ L   +
Sbjct: 93  CQAH-DKV-KLFCLTDRALLCFFCDEPALHEQHQVTGIDDAFDELQRELKDQLQALQDSE 150

Query: 84  QQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQV 143
           ++H + +  ++    + K++ +S +T +   F  L  LL E +    + ++ +T  TL  
Sbjct: 151 REHTEALQLLKRQLAETKSSTKSLRTTIGEAFERLHRLLRERQKAMLEELEADTARTL-- 208

Query: 144 YREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPL 203
                           D+  +V   SQ+   VQ         Q +Q++++  +       
Sbjct: 209 ---------------TDIEQKVQRYSQQLRKVQE------GAQILQERLAETDR------ 241

Query: 204 SFEPVKSFFKGLVEAVESTLQTPLDIRLKESI---NCQLSD-PSSTKPGTLLKTSPSPER 259
                 +F  G+    E         RLK  I   N    D P+S   G L  T     +
Sbjct: 242 -----HTFLAGVASLSE---------RLKGKIHETNLTYEDFPTSKYTGPLQYTI---WK 284

Query: 260 SLLLKYARTP---TLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVL----RFDALWQVL 312
           SL       P   TLDP T H RL LS D   V     G+L P P+     RFD    VL
Sbjct: 285 SLFQDIHPVPAALTLDPGTAHQRLILSDDCTIVA---YGNLHPQPLQDSPKRFDVEVSVL 341

Query: 313 ARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYW 372
             + F++G HYWEV V E    W +G A+ +  R+G+    ++  +R  +C+  +D   +
Sbjct: 342 GSEAFSSGVHYWEVVVAEK-TQWVIGLAHEAASRKGS---IQIQPSRGFYCIVMHDGNQY 397

Query: 373 AFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATF 421
           +      +RL  RD LD++GVFLDY+ G+L FY+    MS L+TFR  F
Sbjct: 398 SACTEPWTRLNVRDKLDKVGVFLDYDQGLLIFYN-ADDMSWLYTFREKF 445


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  104 bits (259), Expect = 2e-22
 Identities = 107/388 (27%), Positives = 162/388 (41%), Gaps = 57/388 (14%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           CP H + +A  FC    R +CA C   G H  H V    +AA  ++   ++ L+ L  + 
Sbjct: 92  CPAHREPLAA-FCGDELRLLCAACERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQM 150

Query: 84  QQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQV 143
           Q  +    Q ++     +   ES +  + G+F  LR LL EEE           Q  LQ 
Sbjct: 151 QDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLAEEE-----------QQLLQR 199

Query: 144 YREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPL 203
             E      E+L+++  L      + Q+   +  L A      E++ +  L  L      
Sbjct: 200 LEE------EELEVLPRLREGAAHLGQQSAHLAELIA------ELEGRCQLPAL------ 241

Query: 204 SFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPER-SLL 262
                     GL++ ++  L+   D++L+         P    P  L      P     L
Sbjct: 242 ----------GLLQDIKDALRRVQDVKLQ---------PPEVVPMELRTVCRVPGLVETL 282

Query: 263 LKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRH 322
            ++    TLDPDT +  L LS DR +V+ G L    P    RFD    VL ++ F +GRH
Sbjct: 283 RRFRGDVTLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRH 342

Query: 323 YWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRL 382
           YWEV+V +    W +G    ++ R+       L      W L      Y   +  +R+  
Sbjct: 343 YWEVEVGDR-TSWALGVCRENVNRK---EKGELSAGNGFWILVFLGSYY---NSSERALA 395

Query: 383 RPRDDLDRLGVFLDYEAGVLAFYDVTGG 410
             RD   R+G+FLDYEAG L+FY  T G
Sbjct: 396 PLRDPPRRVGIFLDYEAGHLSFYSATDG 423


>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
          Length = 517

 Score =  103 bits (258), Expect = 2e-22
 Identities = 113/423 (26%), Positives = 177/423 (41%), Gaps = 33/423 (7%)

Query: 23  RCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQ--LA 80
           RCP HG R  ELFCR   RCVC++C V          L   A +  ++L +E   +  L 
Sbjct: 94  RCPRHG-RPLELFCRTEGRCVCSVCTVRECR------LHERALLDAERLKREAQLRASLE 146

Query: 81  IKKQQHID---NITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNT 137
           + +QQ       + ++   + +++ +A    +W+ GKF+ L   L+ +   A + I+   
Sbjct: 147 VTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAK 206

Query: 138 QLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGEL 197
              L   R++    R  L+ +     R+  + ++ D     Q +    Q +Q    LG L
Sbjct: 207 TQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDE----QTFLQESQLLQPPGPLGPL 262

Query: 198 CHPVPLSFEPVKSF--FKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSP 255
               PL ++  +     K L+  +   L          +    L+   +  P   + ++ 
Sbjct: 263 ---TPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTV 319

Query: 256 SPERSLLLKYARTPTLDPDTMHARLRLSA-DRLTVRCGLLGSLGPVPVLRFDALWQVLAR 314
            P R  L +  R  T DP + +    LS  D+    C    S GP     F+ LWQV   
Sbjct: 320 CPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQ--SRGPGGPGSFE-LWQVQCA 376

Query: 315 DCFATGRHYWEVDVQEAGAGWWVGAAYASLRR-RGASAAARLGCNRQSW--CLKRYDLEY 371
             F  G HYWEV   +      +G +Y  L R R       +G    SW  C++   L+ 
Sbjct: 377 QSFQAGHHYWEVRASDHSVT--LGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQA 434

Query: 372 WAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRL 431
           W  H+G+  RL P      LG+ LD  +G L FY +      L+TF A F +PL P   L
Sbjct: 435 W--HNGEAQRL-PGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWL 491

Query: 432 WEG 434
            EG
Sbjct: 492 LEG 494


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score =  103 bits (257), Expect = 3e-22
 Identities = 113/483 (23%), Positives = 207/483 (42%), Gaps = 81/483 (16%)

Query: 23  RCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIK 82
           +C +H +R+ E FC     C+C +C V   H+        +A+  ++   +  L  +  +
Sbjct: 156 KCSQH-NRLREFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQ 212

Query: 83  KQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLD------------EEEALAK 130
                  +  + +  + ++  A      L+ ++TE++ LLD            EE+ +  
Sbjct: 213 INGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNS 272

Query: 131 KF-------IDKNTQL-TLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQA-- 180
           KF       + K +++ TL+   EQ+ + R++ + +   S ++  IS +P  +  ++   
Sbjct: 273 KFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKAS-KLRGISTKPVYIPEVELNH 331

Query: 181 -------YTATEQEMQQQMSLGELCHPVPLSFEP----------------------VKSF 211
                   +  + + + +  +G L  P P S +P                       KS 
Sbjct: 332 KLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSK 391

Query: 212 FKGLVEAVESTLQT------PLDIR---LKESINCQLSDPSSTK-PGTLLKTSPSPERSL 261
               V A+ S L T       +D++   L+ +     S P+ST     +L+T  +  R  
Sbjct: 392 KPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPE 451

Query: 262 LLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPV------LRFDALWQVLARD 315
           LL+Y     LD +T H ++ LS       C  + S+  +P        RF    QVL   
Sbjct: 452 LLEYYIKVILDYNTAHNKVALS------ECYTVASVAEMPQNYRPHPQRFTYCSQVLGLH 505

Query: 316 CFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFH 375
           C+  G HYWEV++Q+      VG  Y S+ R+G  +  RLG N  SWC++ ++ +  A+H
Sbjct: 506 CYKKGIHYWEVELQKNNF-CGVGICYGSMNRQGPES--RLGRNSASWCVEWFNTKISAWH 562

Query: 376 DGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGA 435
           +     L P     R+GV L+ + G + F+ V   +  ++ FR  F E LYPA  ++   
Sbjct: 563 NNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAG 621

Query: 436 ISI 438
            ++
Sbjct: 622 ATL 624


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score =  102 bits (255), Expect = 5e-22
 Identities = 114/428 (26%), Positives = 182/428 (42%), Gaps = 61/428 (14%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           C  H + ++ LFC + +  +C LC +LG+H+ HPV         +++     + +L  ++
Sbjct: 89  CVHHRNPLS-LFCEKDQELICGLCGLLGSHQHHPVTPVSTVYSRMKEELAALISELKQEQ 147

Query: 84  QQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQ---LT 140
           ++  + I ++ +   ++   ++     ++ +F EL  L+DEE+A   + I  +T+    +
Sbjct: 148 KKVDELIAKLVNNRTRIVNESDVFSWVIRREFQELHHLVDEEKARCLEGIGGHTRGLVAS 207

Query: 141 LQVYREQADSCREQLD----IMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGE 196
           L +  EQA   RE+L     ++    N      ++     R     A+  EM Q      
Sbjct: 208 LDMQLEQAQGTRERLAQAECVLEQFGN------EDHHKFIRKFHSMASRAEMPQ------ 255

Query: 197 LCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPS 256
              P+  +F P+ SF  GL +A         DI+L            +       K  P+
Sbjct: 256 -ARPLEGAFSPI-SFKPGLHQA---------DIKL------------TVWKRLFRKVLPA 292

Query: 257 PERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDC 316
           PE    LK      LDP T H  L LS     V+CGLL         RFD    VLA   
Sbjct: 293 PEP---LK------LDPATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASRG 343

Query: 317 FATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHD 376
           F+ GRHYWEV V  + + W +G    +  R+G             W +   +   +    
Sbjct: 344 FSCGRHYWEV-VVGSKSDWRLGVIKGTASRKG---KLNRSPEHGVWLIGLKEGRVYEAFA 399

Query: 377 GQRSRLRPRDDLDRLGVFLDYEAGVLAFYDV--TGGMSHLHTFRATFQEPLYPAL-RLW- 432
             R  L       R+G++L YE G L F+D      +  L+TF+A FQ  LYP L   W 
Sbjct: 400 CPRVPLPVAGHPHRIGLYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWH 459

Query: 433 -EGAISIP 439
             G+ S+P
Sbjct: 460 ERGSNSLP 467


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  102 bits (254), Expect = 7e-22
 Identities = 109/408 (26%), Positives = 164/408 (40%), Gaps = 59/408 (14%)

Query: 23  RCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIK 82
           RC  HG+ ++  FC      +C +C     HR H      EAA   Q   Q  L+ +  +
Sbjct: 95  RCARHGEDLSR-FCEEDEAALCWVCDAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKE 153

Query: 83  KQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQ 142
            +  +     +   T   K   E  +   + +F + R  L +EE    + ++   + TLQ
Sbjct: 154 LEDALTQEANVGKKTVIWKEKVEMQRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQ 213

Query: 143 VYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVP 202
             RE      +Q   + +L++ +                    QE  Q+ +LG       
Sbjct: 214 RLRESKSRLVQQSKALKELADEL--------------------QERCQRPALG------- 246

Query: 203 LSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPS--PERS 260
                       L+E V   L     +   E+ N  +           LKT+      R 
Sbjct: 247 ------------LLEGVRGVLSRSKAVTRLEAENIPME----------LKTACCIPGRRE 284

Query: 261 LLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATG 320
           LL K+     LDP T H  L L+AD  +V+ G      P    RFD    +L    F++G
Sbjct: 285 LLRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSG 344

Query: 321 RHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRS 380
           RHYWEV V E GA W +G    +L R+G +  +        W LK  +    A       
Sbjct: 345 RHYWEVLVGE-GAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLL 403

Query: 381 RLR-PRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYP 427
           +L  PR     +G+FLDYEAG ++FY+VT G S+++TF   F   L P
Sbjct: 404 QLESPRC----IGIFLDYEAGEISFYNVTDG-SYIYTFNQLFSGLLRP 446


>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
          Length = 564

 Score =  101 bits (252), Expect = 1e-21
 Identities = 116/444 (26%), Positives = 202/444 (45%), Gaps = 53/444 (11%)

Query: 14  SELVEGCGWR-CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLS 72
           +E V+   WR CP H   ++  FC   ++C+C  C     H GH + ++L+AA   ++  
Sbjct: 120 TEPVKDHNWRYCPAHHSPLSA-FCCPDQQCICQDC--CQEHSGHTI-VSLDAARRDKEAE 175

Query: 73  QECLKQLAIKKQQHIDNITQIEDATEKLKANAESS-------KTWLKGKFTELRLLLDEE 125
            +C  QL ++++  ++     E+A  +L+AN +S        K   + +F EL   + + 
Sbjct: 176 LQCT-QLDLERKLKLN-----ENAISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKA 229

Query: 126 EALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATE 185
           +A    F+++  Q  L     QA+  +  L+       R   + +    ++R+ A + T 
Sbjct: 230 QANVMLFLEEKEQAALS----QANGIKAHLEY------RSAEMEKSKQELERMAAISNTV 279

Query: 186 QEMQQQMSLGELCH-PVPLSFEPVKSFFKGLVEAV-ESTLQTPLDIRLKESINCQLSDPS 243
           Q +++            P  +  +K    G+ + + EST+     I+L E+   +L + S
Sbjct: 280 QFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHL---IQLLENYKKKLQEFS 336

Query: 244 S-------TKPGTLLK-----TSPSPE-RSLLLKYARTPTLDPDTMHARLRLSADRLTVR 290
                   T+   +++     + P P  R   L+YA   T DPDT H  LRL  +   V 
Sbjct: 337 KEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVT 396

Query: 291 CGLLGSLGPVPVL--RFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRG 348
                   P P L  RF    QVL++      R+Y+EV++   GAG +VG     + R+G
Sbjct: 397 -NTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI--FGAGTYVGLTCKGIDRKG 453

Query: 349 ASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVT 408
               + +  N  SW L+    E+ A++    + L+      RLGV++D+  G+L+FY V 
Sbjct: 454 EERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLK-AGPFRRLGVYIDFPGGILSFYGVE 512

Query: 409 -GGMSHLHTFRATFQEPLYPALRL 431
              M+ +H F   F EP+Y A  L
Sbjct: 513 YDTMTLVHKFACKFSEPVYAAFWL 536


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 99.0 bits (245), Expect = 8e-21
 Identities = 105/429 (24%), Positives = 176/429 (41%), Gaps = 70/429 (16%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           C  HG+++  LFC+  R+ +C LC     HRGH   L  E     Q+  Q  LK+L  ++
Sbjct: 97  CDHHGEKLL-LFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEE 155

Query: 84  QQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQV 143
           ++       I +     K   ++ +  ++ +F +LR +L+ EE    + +++  + TL  
Sbjct: 156 EEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDK 215

Query: 144 YREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPL 203
           + E  D   +Q  ++ +L + V   SQ             +  E+ Q MS          
Sbjct: 216 FAEAEDELVQQKQLVRELISDVECRSQW------------STMELLQDMS---------- 253

Query: 204 SFEPVKSFFKGLVEAVES-TLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPERSLL 262
                     G+++  E   L+ P  +  K  +      P  ++   + +     E + +
Sbjct: 254 ----------GIMKWSEIWRLKKPKMVSKK--LKTVFHAPDLSRMLQMFR-----ELTAV 296

Query: 263 LKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDAL-WQVLARDCFATGR 321
             Y    TL+   ++  L LS D+  V          VP+  F    + VL    F++G+
Sbjct: 297 RCYWVDVTLNSVNLNLNLVLSEDQRQVIS--------VPIWPFQCYNYGVLGSQYFSSGK 348

Query: 322 HYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDL-EYWAF------ 374
           HYWEVDV +  A  W+   Y     R      R   NRQ+   K   L  YW        
Sbjct: 349 HYWEVDVSKKTA--WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKC 406

Query: 375 ----------HDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTF-RATFQE 423
                      D +   L       R+GVFLDYEAG+++F++VT   S ++ F +  F +
Sbjct: 407 KYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQ 466

Query: 424 PLYPALRLW 432
           P+YP    W
Sbjct: 467 PVYPYFNPW 475


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 99.0 bits (245), Expect = 8e-21
 Identities = 105/429 (24%), Positives = 176/429 (41%), Gaps = 70/429 (16%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           C  HG+++  LFC+  R+ +C LC     HRGH   L  E     Q+  Q  LK+L  ++
Sbjct: 97  CDHHGEKLL-LFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEE 155

Query: 84  QQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQV 143
           ++       I +     K   ++ +  ++ +F +LR +L+ EE    + +++  + TL  
Sbjct: 156 EEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDK 215

Query: 144 YREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPL 203
           + E  D   +Q  ++ +L + V   SQ             +  E+ Q MS          
Sbjct: 216 FAEAEDELVQQKQLVRELISDVECRSQW------------STMELLQDMS---------- 253

Query: 204 SFEPVKSFFKGLVEAVES-TLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPERSLL 262
                     G+++  E   L+ P  +  K  +      P  ++   + +     E + +
Sbjct: 254 ----------GIMKWSEIWRLKKPKMVSKK--LKTVFHAPDLSRMLQMFR-----ELTAV 296

Query: 263 LKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDAL-WQVLARDCFATGR 321
             Y    TL+   ++  L LS D+  V          VP+  F    + VL    F++G+
Sbjct: 297 RCYWVDVTLNSVNLNLNLVLSEDQRQVIS--------VPIWPFQCYNYGVLGSQYFSSGK 348

Query: 322 HYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDL-EYWAF------ 374
           HYWEVDV +  A  W+   Y     R      R   NRQ+   K   L  YW        
Sbjct: 349 HYWEVDVSKKTA--WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKC 406

Query: 375 ----------HDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTF-RATFQE 423
                      D +   L       R+GVFLDYEAG+++F++VT   S ++ F +  F +
Sbjct: 407 KYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQ 466

Query: 424 PLYPALRLW 432
           P+YP    W
Sbjct: 467 PVYPYFNPW 475


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score = 99.0 bits (245), Expect = 8e-21
 Identities = 105/429 (24%), Positives = 176/429 (41%), Gaps = 70/429 (16%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           C  HG+++  LFC+  R+ +C LC     HRGH   L  E     Q+  Q  LK+L  ++
Sbjct: 451 CDHHGEKLL-LFCKEDRKVICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEE 509

Query: 84  QQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQV 143
           ++       I +     K   ++ +  ++ +F +LR +L+ EE    + +++  + TL  
Sbjct: 510 EEAEKLEADIREEKTSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDK 569

Query: 144 YREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPL 203
           + E  D   +Q  ++ +L + V   SQ             +  E+ Q MS          
Sbjct: 570 FAEAEDELVQQKQLVRELISDVECRSQW------------STMELLQDMS---------- 607

Query: 204 SFEPVKSFFKGLVEAVES-TLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPERSLL 262
                     G+++  E   L+ P  +  K  +      P  ++   + +     E + +
Sbjct: 608 ----------GIMKWSEIWRLKKPKMVSKK--LKTVFHAPDLSRMLQMFR-----ELTAV 650

Query: 263 LKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDAL-WQVLARDCFATGR 321
             Y    TL+   ++  L LS D+  V          VP+  F    + VL    F++G+
Sbjct: 651 RCYWVDVTLNSVNLNLNLVLSEDQRQVIS--------VPIWPFQCYNYGVLGSQYFSSGK 702

Query: 322 HYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDL-EYWAF------ 374
           HYWEVDV +  A  W+   Y     R      R   NRQ+   K   L  YW        
Sbjct: 703 HYWEVDVSKKTA--WILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKC 760

Query: 375 ----------HDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTF-RATFQE 423
                      D +   L       R+GVFLDYEAG+++F++VT   S ++ F +  F +
Sbjct: 761 KYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQ 820

Query: 424 PLYPALRLW 432
           P+YP    W
Sbjct: 821 PVYPYFNPW 829



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 10/173 (5%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           C +HG+++ +LFC+   + +C LC     HRGH   L  E A   Q+  QE LK+L  ++
Sbjct: 125 CADHGEKL-QLFCQEDGKVICWLCERSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEE 183

Query: 84  QQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQV 143
           Q+       I +     K   E  +  ++ +F +LR +LD  E    K +++  +  L++
Sbjct: 184 QEAEKLTAFIREKKTSWKNQMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRI 243

Query: 144 YREQADSCREQL----DIMNDLSNRVWSISQE-----PDPVQRLQAYTATEQE 187
             E  +    Q     ++++DL  R    + E      D  +R + +T  + E
Sbjct: 244 IEEAENDLVHQTQSLRELISDLERRCQGSTMELLQDVSDVTERSEFWTLRKPE 296


>gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]
          Length = 329

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 68/172 (39%), Positives = 87/172 (50%), Gaps = 15/172 (8%)

Query: 270 TLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQ 329
           TLDPDT + RL LS D   VR G      P    RFD   +VLA   F++GRH+WEV+V 
Sbjct: 163 TLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVG 222

Query: 330 EAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLD 389
               GW  G A  S+RR+G +           W L+    +YWA    +RS L     L 
Sbjct: 223 SKD-GWAFGVARESVRRKGLTPFTP---EEGVWALQLNGGQYWAVTSPERSPL-SCGHLS 277

Query: 390 RLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA---------LRLW 432
           R+ V LD E G ++FY V   M HL+TFR  FQE ++P          LR+W
Sbjct: 278 RVRVALDLEVGAVSFYAVE-DMRHLYTFRVNFQERVFPLFSVCSTGTYLRIW 328


>gi|154354992 B-box and SPRY domain containing [Homo sapiens]
          Length = 402

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 116/432 (26%), Positives = 181/432 (41%), Gaps = 56/432 (12%)

Query: 19  GCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAH-RGHPVGLALEAAVHVQ-KLSQEC- 75
           G G  CPEHG  ++  FC   RR VCA C  LG   RGH +  A E A  ++ K+  +C 
Sbjct: 17  GPGPLCPEHGQALS-WFCGSERRPVCAACAGLGGRCRGHRIRRAEERAEELRNKIVDQCE 75

Query: 76  ---LKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKF 132
              L+  AI K  ++ ++  +    ++  + A +++  +  + + +R L + EE    + 
Sbjct: 76  RLQLQSAAITK--YVADV--LPGKNQRAVSMASAARELVIQRLSLVRSLCESEEQRLLEQ 131

Query: 133 IDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQM 192
           +    +   Q    Q     E L  ++ +   +  +    D +Q +Q     EQE+ ++ 
Sbjct: 132 VHGEEERAHQSILTQRVHWAEALQKLDTIRTGLVGMLTHLDDLQLIQK----EQEIFERT 187

Query: 193 SLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLK 252
              E                 G+++  ES +       L  +  C  S   +    T + 
Sbjct: 188 EEAE-----------------GILDPQESEM-------LNFNEKCTRSPLLTQLWATAVL 223

Query: 253 TSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSL----GPVPVLRFDAL 308
            S S    +         +D  T+   L+LS DR T+      S     GP    RFD  
Sbjct: 224 GSLSGTEDI--------RIDERTVSPFLQLSDDRKTLTFSTKKSKACADGPE---RFDHW 272

Query: 309 WQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYD 368
              LA   F  G H W V+VQ + A + VG A   L R+G+ +  RLG N  SW   RYD
Sbjct: 273 PNALAATSFQNGLHAWMVNVQNSCA-YKVGVASGHLPRKGSGSDCRLGHNAFSWVFSRYD 331

Query: 369 LEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA 428
            E+   H+GQ   L       +LGV LD +   L FY+   G + L     +F  PL+P 
Sbjct: 332 QEFRFSHNGQHEPLGLLRGPAQLGVVLDLQVQELLFYEPASG-TVLCAHHVSFPGPLFPV 390

Query: 429 LRLWEGAISIPR 440
             + +  ISI R
Sbjct: 391 FAVADQTISIVR 402


>gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 68/172 (39%), Positives = 87/172 (50%), Gaps = 15/172 (8%)

Query: 270 TLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQ 329
           TLDPDT + RL LS D   VR G      P    RFD   +VLA   F++GRH+WEV+V 
Sbjct: 137 TLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVG 196

Query: 330 EAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLD 389
               GW  G A  S+RR+G +           W L+    +YWA    +RS L     L 
Sbjct: 197 SKD-GWAFGVARESVRRKGLTPFTP---EEGVWALQLNGGQYWAVTSPERSPL-SCGHLS 251

Query: 390 RLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA---------LRLW 432
           R+ V LD E G ++FY V   M HL+TFR  FQE ++P          LR+W
Sbjct: 252 RVRVALDLEVGAVSFYAVE-DMRHLYTFRVNFQERVFPLFSVCSTGTYLRIW 302


>gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 68/172 (39%), Positives = 87/172 (50%), Gaps = 15/172 (8%)

Query: 270 TLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQ 329
           TLDPDT + RL LS D   VR G      P    RFD   +VLA   F++GRH+WEV+V 
Sbjct: 137 TLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVG 196

Query: 330 EAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLD 389
               GW  G A  S+RR+G +           W L+    +YWA    +RS L     L 
Sbjct: 197 SKD-GWAFGVARESVRRKGLTPFTP---EEGVWALQLNGGQYWAVTSPERSPL-SCGHLS 251

Query: 390 RLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA---------LRLW 432
           R+ V LD E G ++FY V   M HL+TFR  FQE ++P          LR+W
Sbjct: 252 RVRVALDLEVGAVSFYAVE-DMRHLYTFRVNFQERVFPLFSVCSTGTYLRIW 302


>gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 68/172 (39%), Positives = 87/172 (50%), Gaps = 15/172 (8%)

Query: 270 TLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQ 329
           TLDPDT + RL LS D   VR G      P    RFD   +VLA   F++GRH+WEV+V 
Sbjct: 137 TLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVG 196

Query: 330 EAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLD 389
               GW  G A  S+RR+G +           W L+    +YWA    +RS L     L 
Sbjct: 197 SKD-GWAFGVARESVRRKGLTPFTP---EEGVWALQLNGGQYWAVTSPERSPL-SCGHLS 251

Query: 390 RLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPA---------LRLW 432
           R+ V LD E G ++FY V   M HL+TFR  FQE ++P          LR+W
Sbjct: 252 RVRVALDLEVGAVSFYAVE-DMRHLYTFRVNFQERVFPLFSVCSTGTYLRIW 302


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 99/413 (23%), Positives = 172/413 (41%), Gaps = 40/413 (9%)

Query: 23  RCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIK 82
           +C  H  +V  LFC      +C +C +   H+GH V    E A+  +K  Q+ L+ L   
Sbjct: 374 QCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKL 433

Query: 83  KQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQ 142
           ++   +  +  E+         E+ K  ++ K  ++   L+++E      ++   Q+  Q
Sbjct: 434 RKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQ 493

Query: 143 VYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVP 202
           + +       + + +++ L             +  L+A    + E +    +G++ H   
Sbjct: 494 IRKAYDTRVSQDIALLDAL-------------IGELEAKEC-QSEWELLQDIGDILH--- 536

Query: 203 LSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSD--PSSTK--PGTL---LKTSP 255
                     +     V     TP +I+ K  +  Q S+    STK    TL   ++   
Sbjct: 537 ----------RAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFN 586

Query: 256 SPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARD 315
            PE      +A    LD +T +  L  S D  +VR G      P    RFD+   VL   
Sbjct: 587 VPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSP 646

Query: 316 CFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFH 375
            F +GR YWEV+V +  A W +GA   S+ R+G      L      W +       +   
Sbjct: 647 SFLSGRRYWEVEVGDKTA-WILGACKTSISRKGNMT---LSPENGYWVVIMMKENEYQAS 702

Query: 376 DGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRA-TFQEPLYP 427
               +RL  ++   R+G+F+DY  G ++FY+VT   SH++TF + +F  PL P
Sbjct: 703 SVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVT-ARSHIYTFASCSFSGPLQP 754


>gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo
           sapiens]
          Length = 407

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 65/168 (38%), Positives = 90/168 (53%), Gaps = 7/168 (4%)

Query: 265 YARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYW 324
           +A    LDPDT H  L LS DR +VR G      P    RFD+   VL  + FA+G+HYW
Sbjct: 209 HAADVVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYW 268

Query: 325 EVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRP 384
           EV+V+     W VG    S+ R+G      L      W L+ +  +Y A    +R  L  
Sbjct: 269 EVEVENVMV-WTVGVCRHSVERKG---EVLLIPQNGFWTLEMFGNQYRALSSPERI-LPL 323

Query: 385 RDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTF-RATFQEPLYPALRL 431
           ++ L R+GVFLDYEAG ++FY++    SH++T  R+ F  P+ P  RL
Sbjct: 324 KESLCRVGVFLDYEAGDVSFYNMR-DRSHIYTCPRSAFTVPVRPFFRL 370


>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
           sapiens]
          Length = 523

 Score = 92.8 bits (229), Expect = 6e-19
 Identities = 65/168 (38%), Positives = 90/168 (53%), Gaps = 7/168 (4%)

Query: 265 YARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYW 324
           +A    LDPDT H  L LS DR +VR G      P    RFD+   VL  + FA+G+HYW
Sbjct: 325 HAADVVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYW 384

Query: 325 EVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRP 384
           EV+V+     W VG    S+ R+G      L      W L+ +  +Y A    +R  L  
Sbjct: 385 EVEVENVMV-WTVGVCRHSVERKG---EVLLIPQNGFWTLEMFGNQYRALSSPERI-LPL 439

Query: 385 RDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTF-RATFQEPLYPALRL 431
           ++ L R+GVFLDYEAG ++FY++    SH++T  R+ F  P+ P  RL
Sbjct: 440 KESLCRVGVFLDYEAGDVSFYNMR-DRSHIYTCPRSAFTVPVRPFFRL 486


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score = 92.0 bits (227), Expect = 9e-19
 Identities = 106/418 (25%), Positives = 173/418 (41%), Gaps = 64/418 (15%)

Query: 24  CPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKK 83
           C EHG++   LFC    + +C  C     H+GH   L  +    V +  +E L++   K 
Sbjct: 93  CEEHGEQF-HLFCEDEGQLICWRCERAPQHKGHTTALVED----VCQGYKEKLQKAVTKL 147

Query: 84  QQHIDNITQIEDATE----KLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQL 139
           +Q  D  T+ + +T     K K   +  +  ++  F  L+  L EEE      ++K  Q 
Sbjct: 148 KQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQ 207

Query: 140 TLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCH 199
           TL   R+       +    N+L + +                          + L E C 
Sbjct: 208 TLSRLRDYEAGLGLK---SNELKSHI--------------------------LELEEKC- 237

Query: 200 PVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPS--P 257
                    +   + L++ V  TL     ++L      + S+  S +  T+   S     
Sbjct: 238 ---------QGSAQKLLQNVNDTLSRSWAVKL------ETSEAVSLELHTMCNVSKLYFD 282

Query: 258 ERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCF 317
            + +L  +  + TLDPDT H  L LS DR  V  G           RF A   VL  + F
Sbjct: 283 VKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGF 342

Query: 318 ATGRHYWEVDVQEAGAGWWVGAAYASLRR-RGASAAARLGCNRQSWCLKRYDLEYWAFHD 376
            +GR Y+EVDV E G GW +G    +++R  G     + G     W L+    + +    
Sbjct: 343 TSGRRYFEVDVGE-GTGWDLGVCMENVQRGTGMKQEPQSG----FWTLRLCKKKGYVALT 397

Query: 377 GQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTF-RATFQEPLYPALRLWE 433
              + L   +    +G+FLDYEAGV++FY+   G  H+ TF +A+F + L P  ++++
Sbjct: 398 SPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTG-CHIFTFPKASFSDTLRPYFQVYQ 454


>gi|27734883 tripartite motif family-like 2 [Homo sapiens]
          Length = 387

 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 110/385 (28%), Positives = 172/385 (44%), Gaps = 47/385 (12%)

Query: 63  EAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLL 122
           EAA + +KL QE L                   + EKL    E++K+ L  +  E   ++
Sbjct: 7   EAAENYRKLFQEILNT-----------------SREKL----EAAKSILTDE-QERMAMI 44

Query: 123 DEEEALAKKFIDKNTQLTLQVYREQAD-SCREQLDIMNDLSNRVWSISQEPDPVQRLQAY 181
            EEE   KK I+    + L++  E+ + + + Q + ++DL+ R   ++Q       L+  
Sbjct: 45  QEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEM 104

Query: 182 TATEQEMQQQM------SLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESI 235
               QEM Q++      ++ +L      + E V+S  K +VE  +   +  L +      
Sbjct: 105 F---QEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEGTLALLKNAKY 161

Query: 236 NCQLSDP---SSTKPGTLLKTSPSPERSLLLKYA---RTPTLDPDTMHARLRLSADRLTV 289
           + + S        +P  +   S    R L   +    R  TLDP+T H  L LS D  T+
Sbjct: 162 SLERSKSLLLEHLEPAHITDLSLCHIRGLSSMFRVLQRHLTLDPETAHPCLALSEDLRTM 221

Query: 290 RC--GLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRR 347
           R   G     G    L F A+  VLA + F +GRHYWEVDV++A   W VG  + S   +
Sbjct: 222 RLRHGQQDGAGNPERLDFSAM--VLAAESFTSGRHYWEVDVEKA-TRWQVGIYHGSADAK 278

Query: 348 GASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDV 407
           G++A A       +  +   +   W F   +R  L  +  LD +GVFLD E G ++FY+V
Sbjct: 279 GSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKK--LDTVGVFLDCEHGQISFYNV 336

Query: 408 TGGMSHLHTF-RATFQEPLYPALRL 431
           T  MS ++ F    FQ  L P   L
Sbjct: 337 T-EMSLIYNFSHCAFQGALRPVFSL 360


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,689,488
Number of Sequences: 37866
Number of extensions: 813971
Number of successful extensions: 3077
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 2631
Number of HSP's gapped (non-prelim): 405
length of query: 442
length of database: 18,247,518
effective HSP length: 105
effective length of query: 337
effective length of database: 14,271,588
effective search space: 4809525156
effective search space used: 4809525156
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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