Guide to the Human Genome
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Search of human proteins with 151301154

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|151301154 mucin 6, gastric [Homo sapiens]
         (2439 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|151301154 mucin 6, gastric [Homo sapiens]                         5055   0.0  
gi|116284392 mucin 2 precursor [Homo sapiens]                        1191   0.0  
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]     1009   0.0  
gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]    955   0.0  
gi|161019170 mucin 5AC [Homo sapiens]                                 862   0.0  
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]             817   0.0  
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...   658   0.0  
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...   658   0.0  
gi|89191868 von Willebrand factor preproprotein [Homo sapiens]        557   e-158
gi|169217460 PREDICTED: similar to Mucin-6, partial [Homo sapiens]    542   e-153
gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]             512   e-144
gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]             512   e-144
gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]             512   e-144
gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]             512   e-144
gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]             512   e-144
gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]             512   e-144
gi|134031945 SCO-spondin [Homo sapiens]                               483   e-135
gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Hom...   447   e-125
gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Hom...   447   e-125
gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sap...   447   e-125
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]            325   3e-88
gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo ...   311   4e-84
gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]        311   7e-84
gi|91982772 mucin 17 [Homo sapiens]                                   302   3e-81
gi|239757282 PREDICTED: similar to Fc fragment of IgG binding pr...   281   6e-75
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       281   6e-75
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]           279   2e-74
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]           276   1e-73
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]           276   1e-73
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]           276   1e-73

>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 5055 bits (13113), Expect = 0.0
 Identities = 2439/2439 (100%), Positives = 2439/2439 (100%)

Query: 1    MVQRWLLLSCCGALLSAGLANTSYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFSTFDHHV 60
            MVQRWLLLSCCGALLSAGLANTSYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFSTFDHHV
Sbjct: 1    MVQRWLLLSCCGALLSAGLANTSYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFSTFDHHV 60

Query: 61   YDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGASVVTVSEAIISVKDIGV 120
            YDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGASVVTVSEAIISVKDIGV
Sbjct: 61   YDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGASVVTVSEAIISVKDIGV 120

Query: 121  ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFD 180
            ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFD
Sbjct: 121  ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFD 180

Query: 181  GKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPSTHVRQAQHARICTQLLTLVA 240
            GKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPSTHVRQAQHARICTQLLTLVA
Sbjct: 181  GKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPSTHVRQAQHARICTQLLTLVA 240

Query: 241  PECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVG 300
            PECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVG
Sbjct: 241  PECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVG 300

Query: 301  QCPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCV 360
            QCPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCV
Sbjct: 301  QCPANQVYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCV 360

Query: 361  LHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCT 420
            LHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCT
Sbjct: 361  LHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCT 420

Query: 421  YILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWL 480
            YILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWL
Sbjct: 421  YILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWL 480

Query: 481  PYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDT 540
            PYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDT
Sbjct: 481  PYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDT 540

Query: 541  TDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGT 600
            TDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGT
Sbjct: 541  TDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGT 600

Query: 601  VFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNC 660
            VFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNC
Sbjct: 601  VFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNC 660

Query: 661  TIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQ 720
            TIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQ
Sbjct: 661  TIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQ 720

Query: 721  CPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENK 780
            CPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENK
Sbjct: 721  CPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENK 780

Query: 781  FGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
            FGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA
Sbjct: 781  FGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840

Query: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
            ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG
Sbjct: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900

Query: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPG 960
            VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPG
Sbjct: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPG 960

Query: 961  ALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYV 1020
            ALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYV
Sbjct: 961  ALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYV 1020

Query: 1021 ASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLP 1080
            ASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLP
Sbjct: 1021 ASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLP 1080

Query: 1081 YYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD 1140
            YYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD
Sbjct: 1081 YYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQD 1140

Query: 1141 GHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPT 1200
            GHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPT
Sbjct: 1141 GHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPT 1200

Query: 1201 TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLT 1260
            TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLT
Sbjct: 1201 TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLT 1260

Query: 1261 SSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTST 1320
            SSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTST
Sbjct: 1261 SSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTST 1320

Query: 1321 AQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQP 1380
            AQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQP
Sbjct: 1321 AQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQP 1380

Query: 1381 TRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPE 1440
            TRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPE
Sbjct: 1381 TRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPE 1440

Query: 1441 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAP 1500
            TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAP
Sbjct: 1441 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAP 1500

Query: 1501 PITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAH 1560
            PITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAH
Sbjct: 1501 PITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAH 1560

Query: 1561 TNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFS 1620
            TNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFS
Sbjct: 1561 TNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFS 1620

Query: 1621 TSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQ 1680
            TSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQ
Sbjct: 1621 TSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQ 1680

Query: 1681 ALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSF 1740
            ALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSF
Sbjct: 1681 ALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSF 1740

Query: 1741 STAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTH 1800
            STAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTH
Sbjct: 1741 STAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTH 1800

Query: 1801 SPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTH 1860
            SPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTH
Sbjct: 1801 SPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTH 1860

Query: 1861 TQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPY 1920
            TQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPY
Sbjct: 1861 TQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPY 1920

Query: 1921 HTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS 1980
            HTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS
Sbjct: 1921 HTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS 1980

Query: 1981 TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS 2040
            TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS
Sbjct: 1981 TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS 2040

Query: 2041 TPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSS 2100
            TPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSS
Sbjct: 2041 TPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSS 2100

Query: 2101 RPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVG 2160
            RPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVG
Sbjct: 2101 RPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVG 2160

Query: 2161 TSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPF 2220
            TSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPF
Sbjct: 2161 TSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPF 2220

Query: 2221 TLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRV 2280
            TLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRV
Sbjct: 2221 TLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRV 2280

Query: 2281 PTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGT 2340
            PTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGT
Sbjct: 2281 PTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGT 2340

Query: 2341 PTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPLH 2400
            PTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPLH
Sbjct: 2341 PTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPLH 2400

Query: 2401 SYEQQLELPCPDPSTPGRRLVLTLQVFSHCVCSSVACGD 2439
            SYEQQLELPCPDPSTPGRRLVLTLQVFSHCVCSSVACGD
Sbjct: 2401 SYEQQLELPCPDPSTPGRRLVLTLQVFSHCVCSSVACGD 2439


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 1191 bits (3080), Expect = 0.0
 Identities = 847/2482 (34%), Positives = 1197/2482 (48%), Gaps = 284/2482 (11%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104
            CSTWG  H+ TFD  V+ F G C+Y FA+ C+ ++  F+V L+RGP  + +   VE  + 
Sbjct: 37   CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVE--SI 94

Query: 105  VVTVSEAII------SVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDS 158
            ++T+ +  I      +V +  V+S P+ S GL I       ++ ++     L ++W  + 
Sbjct: 95   LLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSRA---GLTLMWNRED 151

Query: 159  HLMVLVERKYMGQMCGLCGNFDGKVT-NEFVSEEGKFLEPHKFAALQKLDDPGEICTFQD 217
             LM+ ++ K+    CGLCG+++G  + +EF+S+ G    P +F  +QK++ P  +C   +
Sbjct: 152  ALMLELDTKFRNHTCGLCGDYNGLQSYSEFLSD-GVLFSPLEFGNMQKINQPDVVCEDPE 210

Query: 218  IPSTHVRQAQHARICTQLLTLVA-PECS--VSKEPFVLSCQADVAAAPQPGPQNSSCATL 274
                    ++H   C +LLT  A  +C   V  EP++ +CQ D    P  G     C+T+
Sbjct: 211  EEVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRCP--GGDTCVCSTV 268

Query: 275  SEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CSSSCTF 332
            +E+SRQCS  G     WR+  LC    CP N VY E GS C+ TCS+ + S  C      
Sbjct: 269  AEFSRQCSHAGGRPGNWRTATLCPK-TCPGNLVYLESGSPCMDTCSHLEVSSLCEEHRMD 327

Query: 333  GCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERP 392
            GCFCPEGTV +D+ ++  CVPV+QC C LHG +Y PG+     C+ C C  GRWVC + P
Sbjct: 328  GCFCPEGTVYDDIGDSG-CVPVSQCHCRLHGHLYTPGQEITNDCEQCVCNAGRWVCKDLP 386

Query: 393  CPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLV 452
            CPG C+LEGGS +TTFD + Y FHG C Y+L +     +  AL+      G +  +T L 
Sbjct: 387  CPGTCALEGGSHITTFDGKTYTFHGDCYYVLAKGDH-NDSYALLGELAPCGSTDKQTCLK 445

Query: 453  AVVYLSRQDK--IVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQ 510
             VV L+ + K  +V   D  V  N     LP+ T + +VFR +S H+ ++ + G+ L VQ
Sbjct: 446  TVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQ 505

Query: 511  LRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA-GNCPA 569
            L P+ Q +VT+    +GQ +GLCGNFNG   DDF T+ G+ E T + F ++W+A  +C  
Sbjct: 506  LAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHD 565

Query: 570  ALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETF 629
             L+   DPCS++  +   AE  CS+L +T T F RCH+ V+PA +YKRC Y  CN +   
Sbjct: 566  KLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNCQNNE 625

Query: 630  PHICAALGDYVHACSLRGVLLWGWRSSVDNCTI-PCTGNTTFSYNSQACERTCLSLSDRA 688
              +CAAL  Y  AC+ +GV+LWGWR  V N  +  C  +  F YN   C++TC SLS+  
Sbjct: 626  DCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEAD 685

Query: 689  TECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCIN 748
            + C     PVDGC CPD T+L++KG CV  A+C C   G  ++ A    V     C C +
Sbjct: 686  SHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGL-YLEAGDVVVRQEERCVCRD 744

Query: 749  GRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCV 808
            GRL C Q  ++   SC APK    CS  +        A +CQ LA G     T+C  GCV
Sbjct: 745  GRLHCRQI-RLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGY--YHTECVSGCV 801

Query: 809  CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTC 868
            C +GL ++  G CV  +ECPC  +   Y  GA++  DC TC+C RGRW C Q   C  TC
Sbjct: 802  CPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAV-CHGTC 860

Query: 869  TLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAI 928
            ++YG GH ITFDG+ + FDG+C Y+   D CG N S  +F I+TENV CG +GVTCS+AI
Sbjct: 861  SIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAI 920

Query: 929  KIFLGGLSVVLADRNYTVT--GEEPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTI 986
            KIF+G   + L D++  V    E  HV          LVV+ S      + +IW++  T+
Sbjct: 921  KIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESST----GIIVIWDKRTTV 976

Query: 987  LIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDVSFVTDP 1046
             I++A + +  +CGLCGNF+    +DF TR   V SSEL+  NSWKE+P C DVS   +P
Sbjct: 977  FIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDVSTNPEP 1036

Query: 1047 CSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVA 1106
            CSLN  RRSWAE++CS++ S  F+ CHSKV   P+YEACV D+C CD+GGDCEC C AVA
Sbjct: 1037 CSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECFCSAVA 1096

Query: 1107 AYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPC------ 1160
            +YAQ C  +G CV WRTP  CPI+C +YN   +             C WHY+PC      
Sbjct: 1097 SYAQECTKEGACVFWRTPDLCPIFCDYYNPPHE-------------CEWHYEPCGNRSFE 1143

Query: 1161 ---LCPSQPQSVPGSNIEGCY-NCSQDE-YFDHEEGVCVP-----CMPPTTPQPP--TTP 1208
                      ++  S +EGCY  C +D   ++ +   CV      C    T  PP  + P
Sbjct: 1144 TCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTHYPPGASVP 1203

Query: 1209 QLPTTGS-----------RPTQ-------------VWPMTGTSTTI----GLLS-STGPS 1239
               T  S           RP +              W + G + T+     + S +T PS
Sbjct: 1204 TEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNICSITTRPS 1263

Query: 1240 PSSNHTPAS-PTQTPLLPATLTSSKPTASSGEPPRPTTAVT---------PQATSGLPPT 1289
              +  T  + PT       T T++ PT+S+     P              P + S     
Sbjct: 1264 TLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGSDDGDR 1323

Query: 1290 ATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSP-----TLP 1344
             T       P   +  +      +        Q               G  P        
Sbjct: 1324 ETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQCDVSVGFICKNEDQFGNGPFGLCYDYK 1383

Query: 1345 KSTNQELPGTTATQTTGPRPTPAS---TTGPTTPQPGQPTRPTATETTQTRTTT-----E 1396
               N   P      T  P  T  S   T+  T P    P+ PT T TT   TTT      
Sbjct: 1384 IRVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT 1443

Query: 1397 YTTPQTPHTTHSPP--TAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSL 1454
             TT   P TT SPP  T  +P P+T P   T+  +  T  TPS P TT  T  P   T+ 
Sbjct: 1444 TTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPT-TTPSPPTTTTTTPPP---TTT 1499

Query: 1455 VTPSTHTVITP---THAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQ 1511
             +P T T ITP   T     T+  +    T T PPPTT   T S  T  PITP TS T+ 
Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTT---TPSPPTTTPITPPTSTTTL 1556

Query: 1512 AHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPP 1571
              ++ + +  PT     T++T  P  TP+  TT TP+P +  T T             PP
Sbjct: 1557 PPTT-TPSPPPT-----TTTTPPPTTTPSPPTTTTPSPPTITTTT-------------PP 1597

Query: 1572 PFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLP---THVPPFSTSLVTPST 1628
            P TT SPPT +   ++T P T T    TTT  TP    TTLP   T  PP +T+   P T
Sbjct: 1598 PTTTPSPPTTT---TTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1654

Query: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHT--APTMTLTTSGTSQALSSLN 1686
             T   PT     T+     + T T PPPTT  ++  T T   PT T+TT   +   SS  
Sbjct: 1655 TTPSPPT-----TTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPI 1709

Query: 1687 TAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS 1746
            T  T+ S     S+T  +   +T T   TP+PT+T +PP   TT+ T+   ++ S+  T+
Sbjct: 1710 TTTTTPS-----STTTPSPPPTTMT---TPSPTTTPSPP---TTTMTTLPPTTTSSPLTT 1758

Query: 1747 TSL-HSHTSSTHHPEVTSTSTT-------------SITPNHTSTGTRTPV---------A 1783
            T L  S T  T  P  T+T TT             S  PN    G  T +         A
Sbjct: 1759 TPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWA 1818

Query: 1784 HTTSATSSRLPTPFTTHSPPTGTTPIS----------STGPVTATSFQTTTTYPTPSHPH 1833
               S  ++  P         T    +S            G V   +F             
Sbjct: 1819 ANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCEC 1878

Query: 1834 TTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAP 1893
             T PT + + +T   TP T T I  T T   T       PTGT  P TT   T +T T  
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTP- 1932

Query: 1894 PMTPTTSGTSQSPSSFSTAKTSTSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPV 1951
              TPT +GT Q+P++     T+T  P  T + T  P  TP T+TT +TP  T TGT+TP 
Sbjct: 1933 --TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 1989

Query: 1952 AH--TTSASSSRLPTPFTTHSPPT-----------GSSPFSSTGPMTATSFQTTTTYPTP 1998
                TT+ + +  PTP  T +P T             +P  +  P T     TTT  PTP
Sbjct: 1990 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2049

Query: 1999 SHPQTTLPTHVPPFSTSLVTPS---------THTVIITTHTQMATSASIHSTPTGTVPPP 2049
            +   T  PT  P  +T+ VTP+         T T I TT T   T      TPTGT  P 
Sbjct: 2050 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPT 2104

Query: 2050 TTLKATGSTHTAPP-----MTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPS 2104
            TT   T +T T  P      T TT+  + T +   T T + +   +++ +   ++  P  
Sbjct: 2105 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2164

Query: 2105 SPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSS 2164
            +P  TQ P     TTP++TT  ++   +P+P+   T ++  P + ++  T +P+   + +
Sbjct: 2165 TPTGTQTP----TTTPITTTTTVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT 2217

Query: 2165 FVSAPVHSTTLSSGSHSSLSTH-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTL 2222
              + P+ +TT  + + +   T  PTT  + + + + P+     T    T P T ++  T 
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2277

Query: 2223 SALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPT 2282
            +   P  T T +PT +    ++T+    TP  T +  T P  ++ + T   T   T+ PT
Sbjct: 2278 T---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2334

Query: 2283 SGFVSLTSGVTGIP---------TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS- 2328
            +  ++ T+ VT  P         T+P+T  TT  P P    T +PTT  +T++ T   + 
Sbjct: 2335 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2394

Query: 2329 ------TPASAPVSSLGTPTPT 2344
                  TP + P+++  T TPT
Sbjct: 2395 TPTGTQTPTTTPITTTTTVTPT 2416



 Score =  458 bits (1179), Expect = e-128
 Identities = 401/1257 (31%), Positives = 574/1257 (45%), Gaps = 143/1257 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2185 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2243

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2244 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2355

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2410

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2411 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2469

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2470 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2527

Query: 1545 ITPNPTSTRTRTPVAH--TNSATSSRPPPPFTTHSPPT-----------GSSPFSSTGPM 1591
            +TP PT T T+TP     T + T +  P P  T +P T             +P  +  P 
Sbjct: 2528 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2587

Query: 1592 TATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
            T     TTT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2588 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2648 TPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706

Query: 1709 TSTTNITPNPTSTG-----TPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TG     T P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766

Query: 1764 ---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
                     T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2767 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826

Query: 1815 VTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-VIIPT 1859
            VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T    PT
Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886

Query: 1860 HTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSL 1918
             T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+T  
Sbjct: 2887 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTTTVT 2943

Query: 1919 PYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSPPT- 1973
            P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P T 
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3003

Query: 1974 ----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS--- 2020
                        +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+   
Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3063

Query: 2021 ------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTVTTS 2069
                  T T I TT T   T      TPTGT  P TT   T +T T  P      T TT+
Sbjct: 3064 TGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3118

Query: 2070 GTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSS 2129
              + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  ++ 
Sbjct: 3119 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTP 3174

Query: 2130 SFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH-PT 2188
              +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T  PT
Sbjct: 3175 --TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231

Query: 2189 TASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIA 2247
            T  + + + + P+     T    T P T ++  T +   P  T T +PT +    ++T+ 
Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVT 3288

Query: 2248 FPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP---------TS 2298
               TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P         T+
Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348

Query: 2299 PVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
            P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3349 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3405



 Score =  458 bits (1179), Expect = e-128
 Identities = 401/1257 (31%), Positives = 574/1257 (45%), Gaps = 143/1257 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2611

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2723

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2724 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2778

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2779 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2837

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2838 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2895

Query: 1545 ITPNPTSTRTRTPVAH--TNSATSSRPPPPFTTHSPPT-----------GSSPFSSTGPM 1591
            +TP PT T T+TP     T + T +  P P  T +P T             +P  +  P 
Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955

Query: 1592 TATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
            T     TTT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074

Query: 1709 TSTTNITPNPTSTG-----TPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TG     T P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3134

Query: 1764 ---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
                     T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 3135 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3194

Query: 1815 VTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-VIIPT 1859
            VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T    PT
Sbjct: 3195 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3254

Query: 1860 HTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSL 1918
             T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+T  
Sbjct: 3255 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTTTVT 3311

Query: 1919 PYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSPPT- 1973
            P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P T 
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3371

Query: 1974 ----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS--- 2020
                        +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+   
Sbjct: 3372 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3431

Query: 2021 ------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTVTTS 2069
                  T T I TT T   T      TPTGT  P TT   T +T T  P      T TT+
Sbjct: 3432 TGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486

Query: 2070 GTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSS 2129
              + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  ++ 
Sbjct: 3487 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTP 3542

Query: 2130 SFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH-PT 2188
              +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T  PT
Sbjct: 3543 --TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3599

Query: 2189 TASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIA 2247
            T  + + + + P+     T    T P T ++  T +   P  T T +PT +    ++T+ 
Sbjct: 3600 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVT 3656

Query: 2248 FPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP---------TS 2298
               TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P         T+
Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3716

Query: 2299 PVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
            P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3717 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3773



 Score =  458 bits (1179), Expect = e-128
 Identities = 401/1257 (31%), Positives = 574/1257 (45%), Gaps = 143/1257 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2979

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3036

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3091

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3092 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3146

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3147 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3205

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3206 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3263

Query: 1545 ITPNPTSTRTRTPVAH--TNSATSSRPPPPFTTHSPPT-----------GSSPFSSTGPM 1591
            +TP PT T T+TP     T + T +  P P  T +P T             +P  +  P 
Sbjct: 3264 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3323

Query: 1592 TATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
            T     TTT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 3324 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3383

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 3384 TPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442

Query: 1709 TSTTNITPNPTSTG-----TPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TG     T P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 3443 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3502

Query: 1764 ---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
                     T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 3503 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3562

Query: 1815 VTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-VIIPT 1859
            VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T    PT
Sbjct: 3563 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3622

Query: 1860 HTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSL 1918
             T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+T  
Sbjct: 3623 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTTTVT 3679

Query: 1919 PYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSPPT- 1973
            P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P T 
Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3739

Query: 1974 ----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS--- 2020
                        +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+   
Sbjct: 3740 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3799

Query: 2021 ------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTVTTS 2069
                  T T I TT T   T      TPTGT  P TT   T +T T  P      T TT+
Sbjct: 3800 TGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3854

Query: 2070 GTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSS 2129
              + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  ++ 
Sbjct: 3855 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTP 3910

Query: 2130 SFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH-PT 2188
              +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T  PT
Sbjct: 3911 --TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3967

Query: 2189 TASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIA 2247
            T  + + + + P+     T    T P T ++  T +   P  T T +PT +    ++T+ 
Sbjct: 3968 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVT 4024

Query: 2248 FPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP---------TS 2298
               TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P         T+
Sbjct: 4025 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4084

Query: 2299 PVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
            P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 4085 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4141



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2231 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2289

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2290 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2346

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2401

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2456

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2457 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2515

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2516 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2573

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2574 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2633

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2634 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2689

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2690 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2748

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2749 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2808

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2868

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2928

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 2929 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 2985

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3045

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3105

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3160

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3216

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3217 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3330

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3331 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450

Query: 2344 T 2344
            T
Sbjct: 3451 T 3451



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2254 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2312

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2369

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2370 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2424

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2425 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2479

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2480 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2538

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2539 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2596

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2597 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2656

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2657 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2712

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2713 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2771

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2772 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2831

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2832 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2891

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2951

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 2952 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3008

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3009 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3068

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3183

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3239

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3240 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3353

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3354 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473

Query: 2344 T 2344
            T
Sbjct: 3474 T 3474



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2335

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2392

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2393 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2447

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2448 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2502

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2503 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2561

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2562 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2679

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2680 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2735

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2794

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2795 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2854

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2855 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2914

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2974

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 2975 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3031

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3032 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3091

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3092 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3206

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3262

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3263 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3319

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3320 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3376

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3377 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3436

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496

Query: 2344 T 2344
            T
Sbjct: 3497 T 3497



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2358

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2415

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2470

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2471 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2525

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2526 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2584

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2585 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2642

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2643 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2702

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2758

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2759 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2817

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2818 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2877

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2878 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 2998 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3054

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3055 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3114

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3285

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3286 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3342

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3343 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3399

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3519

Query: 2344 T 2344
            T
Sbjct: 3520 T 3520



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2381

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2438

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2493

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2548

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2549 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2607

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2608 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2665

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2666 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2725

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2726 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2781

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2782 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2840

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2960

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3077

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3078 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3137

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3197

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3308

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3309 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3422

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3423 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3482

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3542

Query: 2344 T 2344
            T
Sbjct: 3543 T 3543



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2404

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2516

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2517 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2571

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2572 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2630

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2631 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2748

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2749 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2804

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2863

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2864 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2983

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3100

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3101 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3160

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3161 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3220

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3275

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3331

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3332 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3388

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3389 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3445

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565

Query: 2344 T 2344
            T
Sbjct: 3566 T 3566



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2369 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2427

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2484

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2539

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2540 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2594

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2595 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2653

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2654 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2711

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2712 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2771

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2772 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2827

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2828 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2886

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2887 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2946

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2947 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3006

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3066

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3067 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3123

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3183

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3298

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3354

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3355 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3411

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3468

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3469 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3588

Query: 2344 T 2344
            T
Sbjct: 3589 T 3589



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2450

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2507

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2562

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2563 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2617

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2618 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2676

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2677 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2734

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2735 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2794

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2795 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2850

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2851 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2909

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2910 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2969

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2970 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3029

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3146

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3147 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3206

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3266

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3377

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3378 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3491

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3492 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611

Query: 2344 T 2344
            T
Sbjct: 3612 T 3612



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2473

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2530

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2585

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2640

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2641 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2699

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2700 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2757

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2817

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2818 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2873

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2932

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2933 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2992

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3052

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3112

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3113 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3169

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3229

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3230 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3400

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3401 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3514

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3515 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634

Query: 2344 T 2344
            T
Sbjct: 3635 T 3635



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2496

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2553

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2608

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2609 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2663

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2664 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2722

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2723 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2780

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2781 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2840

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2896

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2955

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3136 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3192

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3193 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3252

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3253 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3312

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3367

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3368 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3423

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3424 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3480

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3537

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3657

Query: 2344 T 2344
            T
Sbjct: 3658 T 3658



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2519

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2576

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2631

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2632 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2686

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2687 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2745

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2746 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2803

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2804 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2863

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2864 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2919

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2920 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 2978

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 2979 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3038

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3098

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3215

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3216 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3275

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3276 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3335

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3446

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3447 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3503

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3504 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3560

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3561 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3680

Query: 2344 T 2344
            T
Sbjct: 3681 T 3681



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2542

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2599

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2654

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2709

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2710 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2768

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2769 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2826

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2887 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2942

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2943 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3001

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3002 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3061

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3062 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3121

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3181

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3182 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3238

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3239 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3298

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3358

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3469

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3470 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3526

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3527 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3583

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703

Query: 2344 T 2344
            T
Sbjct: 3704 T 3704



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2507 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2565

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2622

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2677

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2678 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2732

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2733 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2791

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2792 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2849

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2850 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2909

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2910 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2965

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2966 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3024

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3025 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3084

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3085 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3144

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3204

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3205 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3261

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3321

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3381

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3436

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3492

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3493 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3606

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3726

Query: 2344 T 2344
            T
Sbjct: 3727 T 3727



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2588

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2645

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2700

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2701 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2755

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2756 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2814

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2815 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2872

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2873 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2932

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2933 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 2988

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 2989 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3047

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3048 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3107

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3108 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3167

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3227

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3228 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3284

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3285 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3344

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3404

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3515

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3516 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3572

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3573 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3629

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3630 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749

Query: 2344 T 2344
            T
Sbjct: 3750 T 3750



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2576 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2634

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2746

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2747 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2801

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2802 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2860

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2861 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2918

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2919 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2978

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 2979 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3034

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3035 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3093

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3094 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3153

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3330

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3331 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3390

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3391 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3450

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3561

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3562 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3618

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3619 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3675

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3676 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3735

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3795

Query: 2344 T 2344
            T
Sbjct: 3796 T 3796



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2657

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2769

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2770 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2824

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2825 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2883

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2884 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2941

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2942 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3001

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3002 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3057

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3058 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3116

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3236

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3353

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3354 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3413

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3414 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3473

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3584

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3585 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3642 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3698

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3699 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3818

Query: 2344 T 2344
            T
Sbjct: 3819 T 3819



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2680

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2737

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2792

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2793 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2847

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2848 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2906

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2907 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2964

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3024

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3025 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3080

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3081 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3139

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3140 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3199

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3200 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3259

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3319

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3320 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3376

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3377 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3436

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3437 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3607

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3608 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3664

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3665 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3721

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3841

Query: 2344 T 2344
            T
Sbjct: 3842 T 3842



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2703

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2760

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2815

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2816 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2870

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2871 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2929

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2930 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2987

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2988 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3047

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3048 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3103

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3104 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3162

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3222

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3223 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3282

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3342

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3343 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3399

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3459

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3460 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3519

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3630

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3631 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3687

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3688 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3744

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3745 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3804

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3805 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3864

Query: 2344 T 2344
            T
Sbjct: 3865 T 3865



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2726

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2783

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2838

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2839 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2893

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2894 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2952

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2953 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3010

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3011 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3070

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3071 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3126

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3127 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3185

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3246 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3305

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3422

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3423 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3482

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3483 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3542

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3653

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3654 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3767

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3768 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3827

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3828 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3887

Query: 2344 T 2344
            T
Sbjct: 3888 T 3888



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2749

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2806

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2861

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2862 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2916

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2917 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2975

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2976 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3093

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3094 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3149

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3150 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3208

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3209 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3268

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3269 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3328

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3388

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3389 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3445

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3505

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3506 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3676

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3677 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3733

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3734 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3790

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3791 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3850

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3851 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3910

Query: 2344 T 2344
            T
Sbjct: 3911 T 3911



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2772

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2829

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2884

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2885 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2939

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2940 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2998

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2999 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3056

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3057 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3116

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3172

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3173 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3231

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3291

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3292 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3411

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3468

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3469 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3528

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3529 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3588

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3699

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3700 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3756

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3757 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3813

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3873

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3933

Query: 2344 T 2344
            T
Sbjct: 3934 T 3934



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2795

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2852

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2907

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2908 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2962

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2963 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3021

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3022 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3079

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3080 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3139

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3140 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3195

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3196 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3254

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3255 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3314

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3374

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3491

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3492 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3551

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3611

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3722

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3723 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3779

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3780 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3836

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3837 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3896

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3897 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3956

Query: 2344 T 2344
            T
Sbjct: 3957 T 3957



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2818

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2875

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2930

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2931 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2985

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2986 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3044

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3045 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3102

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3218

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3219 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3277

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3278 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3337

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3338 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3397

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3514

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3515 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3574

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3745

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3746 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3802

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3803 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3859

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3860 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3919

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3920 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3979

Query: 2344 T 2344
            T
Sbjct: 3980 T 3980



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2841

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2898

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2953

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2954 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3008

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3009 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3067

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3068 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3125

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3126 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3185

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3241

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3242 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3300

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3301 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3360

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3361 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3420

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3480

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3537

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3657

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3713 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3768

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3769 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3826 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3882

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3883 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3942

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3943 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4002

Query: 2344 T 2344
            T
Sbjct: 4003 T 4003



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2864

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2921

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2976

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2977 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3031

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3032 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3090

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3091 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3148

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3149 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3208

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3209 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3264

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3265 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3323

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3324 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3383

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3384 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3443

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3503

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3504 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3560

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3561 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3620

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3621 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3680

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3735

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3736 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3791

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3792 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3848

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3849 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3905

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3906 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3965

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3966 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4025

Query: 2344 T 2344
            T
Sbjct: 4026 T 4026



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2887

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2944

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2999

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3000 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3054

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3055 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3113

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3114 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3171

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3172 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3287

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3346

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3347 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3406

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3407 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3466

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3526

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3527 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3583

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3643

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3644 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3814

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3815 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3871

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3872 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3928

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3929 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3988

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 3989 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4048

Query: 2344 T 2344
            T
Sbjct: 4049 T 4049



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2852 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2910

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2967

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3022

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3023 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3077

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3078 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3136

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3137 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3194

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3195 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3254

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3255 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3310

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3311 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3369

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3370 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3429

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3430 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3606

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3666

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3726

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3837

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3838 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3894

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3895 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3951

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4011

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 4012 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4071

Query: 2344 T 2344
            T
Sbjct: 4072 T 4072



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2933

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2990

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3045

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3046 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3100

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3101 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3159

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3160 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3217

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3218 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3277

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3278 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3333

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3334 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3392

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3393 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3453 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3512

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3572

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3573 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3629

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3630 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3689

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3690 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3749

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3804

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3805 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3860

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3861 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3917

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3918 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3974

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3975 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4034

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 4035 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4094

Query: 2344 T 2344
            T
Sbjct: 4095 T 4095



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2956

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3068

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3123

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3124 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3182

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3183 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3240

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3241 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3301 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3356

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3415

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3416 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3475

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3476 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3535

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3595

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3596 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3652

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3653 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3712

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3713 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3772

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3773 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3827

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3828 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3883

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3884 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3940

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3941 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 3997

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 3998 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4057

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 4058 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4117

Query: 2344 T 2344
            T
Sbjct: 4118 T 4118



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 3002

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3059

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3114

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3169

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3170 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3228

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3229 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3286

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3287 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3346

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3347 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3402

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3403 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3461

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3462 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3521

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3522 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3581

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3641

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3642 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3698

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3699 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3758

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3818

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3873

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3874 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3929

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3930 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3986

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 3987 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 4043

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 4044 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4103

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 4104 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4163

Query: 2344 T 2344
            T
Sbjct: 4164 T 4164



 Score =  458 bits (1178), Expect = e-128
 Identities = 401/1261 (31%), Positives = 578/1261 (45%), Gaps = 151/1261 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 3025

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3082

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3137

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3138 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3192

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3193 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3251

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3252 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3309

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3370 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3425

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3426 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3484

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3485 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3544

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3545 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3604

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3664

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3665 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3721

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3841

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3842 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3896

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3897 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 3952

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 3953 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4009

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 4010 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 4066

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 4067 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4126

Query: 2297 --TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTP 2343
              T+P+T  TT  P P    T +PTT  +T++ T   +       TP + P+++  T TP
Sbjct: 4127 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4186

Query: 2344 T 2344
            T
Sbjct: 4187 T 4187



 Score =  457 bits (1176), Expect = e-128
 Identities = 408/1293 (31%), Positives = 586/1293 (45%), Gaps = 166/1293 (12%)

Query: 1158 QPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPTTPQPPTTPQLPTTGSRP 1217
            Q C C +QP ++  +  E                   P  P TTP   TT   PT    P
Sbjct: 1874 QCCECVTQPTTMTTTTTEN------------------PTPPTTTPITTTTTVTPT----P 1911

Query: 1218 TQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTA 1277
            T     T T+T I   ++  P+P+   T  +PT TP+   T  +  PT +  + P  T  
Sbjct: 1912 TPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1970

Query: 1278 VTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATS 1337
             T   T+ + PT T   T T  T    TT     T +P  T T  +T  TT T  TP  +
Sbjct: 1971 TT---TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2027

Query: 1338 GTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATET---TQTRTT 1394
             T    P +T    P TT T  T P PTP  T  PTT      T  T T T   TQT TT
Sbjct: 2028 PTGTQTPTTT----PITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2082

Query: 1395 TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSL 1454
            T  TT  T   T +P   G+  P+T P+T T    TT  PTP+   T  PT  P  +T+ 
Sbjct: 2083 TPITTTTT--VTPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTPTTTPITTTTT 2136

Query: 1455 VTPS-THT-VITPTHAQMATSASNHSAPTGT-IPPPTTLKATGSTHTAPPITPTTSGTSQ 1511
            VTP+ T T   TPT   + T+ +    PT T    PTT   T +T   P  TPT +GT  
Sbjct: 2137 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQT 2194

Query: 1512 AHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTTITPNPTSTRTRTPVAHTNSATSSRPP 1570
              ++  T  T  +     + T  P  TP T+TTT+TP PT T T+TP     + T++  P
Sbjct: 2195 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2254

Query: 1571 PPFTTHSPPTGSSPFSSTGPMTATSFKT-------------TTTYPTPSHPQTTLPTHVP 1617
             P  T +    ++P ++T  +T T   T             TT  PTP+   T  PT  P
Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314

Query: 1618 PFSTSLVTPS-THT-VITPTHAQMATSASIHSMPTGT-IPPPTTLKATGSTHTAPTMTLT 1674
              +T+ VTP+ T T   TPT   + T+ ++   PT T    PTT   T +T   PT T T
Sbjct: 2315 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2374

Query: 1675 TSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTP-----PMTVT 1729
             + T    + + T  T T   + T +        T+TT +TP PT TGT      P+T T
Sbjct: 2375 GTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2433

Query: 1730 TSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTST---------STTSITPNHTSTGTRT 1780
            T+ T     + +   T+T + + T+ T  P  T T         +TT++TP  T TGT+T
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2493

Query: 1781 PVAH--TTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATS-------------FQTTTT 1825
            P     TT+ T +  PTP  T +P   TTPI++T  VT T                TTT 
Sbjct: 2494 PTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2551

Query: 1826 YPTPSHPHTTLPTHVPSFSTSLVTPS-THT-VIIPTHTQMATSASIHSMPTGT-IPPPTT 1882
             PTP+   T  PT  P  +T+ VTP+ T T    PT T + T+ ++   PT T    PTT
Sbjct: 2552 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611

Query: 1883 IKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHT-SSTHHPEVTP-TSTTNITP 1940
               T +T   P  TPT +GT Q+P++     T+T  P  T + T  P  TP T+TT +TP
Sbjct: 2612 TPITTTTTVTP--TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2668

Query: 1941 KHTSTGTRTPVAH--TTSASSSRLPTPFTTHSPPT-----------GSSPFSSTGPMTAT 1987
              T TGT+TP     TT+ + +  PTP  T +P T             +P  +  P T  
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728

Query: 1988 SFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS---------THTVIITTHTQMATSASI 2038
               TTT  PTP+   T  PT  P  +T+ VTP+         T T I TT T   T    
Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---- 2784

Query: 2039 HSTPTGTVPPPTTLKATGSTHTAPP-----MTVTTSGTSQTHSSFSTATASSSFISSSSW 2093
              TPTGT  P TT   T +T T  P      T TT+  + T +   T T + +   +++ 
Sbjct: 2785 -PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2843

Query: 2094 LPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQ 2153
            +   ++  P  +P  TQ P     TTP++TT  ++   +P+P+   T ++  P + ++  
Sbjct: 2844 ITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTP--TPTPTGTQTPTT-TPITTTTTV 2896

Query: 2154 TSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH-PTTASV-SASPLFPSSPAASTTIRAT 2211
            T +P+   + +  + P+ +TT  + + +   T  PTT  + + + + P+     T    T
Sbjct: 2897 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956

Query: 2212 LPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTS 2271
             P T ++  T +   P  T T +PT +    ++T+    TP  T +  T P  ++ + T 
Sbjct: 2957 TPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3013

Query: 2272 RSTSLTTRVPTSGFVSLTSGVTGIP---------TSPVTNLTTRHPGP----TLSPTTRF 2318
              T   T+ PT+  ++ T+ VT  P         T+P+T  TT  P P    T +PTT  
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073

Query: 2319 LTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
            +T++ T   +       TP + P+++  T TPT
Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3106



 Score =  455 bits (1171), Expect = e-127
 Identities = 395/1234 (32%), Positives = 570/1234 (46%), Gaps = 127/1234 (10%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 3071

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3183

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3184 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3238

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3239 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3297

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3298 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3355

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3356 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3415

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3416 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3471

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3472 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3530

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3591 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3650

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3767

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPP 1972
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     + +++  PTP  T +  
Sbjct: 3768 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3827

Query: 1973 TGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQM 2032
              ++P ++T  +T T   T T  PT +   TT      P  T   TP+T T I TT T  
Sbjct: 3828 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVT 3886

Query: 2033 ATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTVTTSGTSQTHSSFSTATASSSF 2087
             T      TPTGT  P TT   T +T T  P      T TT+  + T +   T T + + 
Sbjct: 3887 PT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3941

Query: 2088 ISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPS 2147
              +++ +   ++  P  +P  TQ P     TTP++TT  ++   +P+P+   T ++  P 
Sbjct: 3942 TPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTP--TPTPTGTQTPTT-TPI 3994

Query: 2148 SHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH-PTTASV-SASPLFPSSPAAS 2205
            + ++  T +P+   + +  + P+ +TT  + + +   T  PTT  + + + + P+     
Sbjct: 3995 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4054

Query: 2206 TTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFS 2265
            T    T P T ++  T +   P  T T +PT +    ++T+    TP  T +  T P  +
Sbjct: 4055 TQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4111

Query: 2266 SQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP---------TSPVTNLTTRHPGP----TL 2312
            + + T   T   T+ PT+  ++ T+ VT  P         T+P+T  TT  P P    T 
Sbjct: 4112 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4171

Query: 2313 SPTTRFLTSSLTAHGSTPASAPV-SSLGTPTPTS 2345
            +PTT  +T++ T    TP   P  +  G PT TS
Sbjct: 4172 TPTTTPITTTTTV---TPTPTPTGTQTGPPTHTS 4202



 Score =  455 bits (1171), Expect = e-127
 Identities = 402/1268 (31%), Positives = 577/1268 (45%), Gaps = 152/1268 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 3094

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3151

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3206

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3207 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3261

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3262 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3320

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3321 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3378

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3379 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3439 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3494

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3495 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3553

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3554 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3613

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3614 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3733

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3734 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3790

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3791 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3850

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3851 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3910

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3965

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 3966 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 4021

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 4022 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4078

Query: 2186 H-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
              PTT  + + + + P+     T    T P T ++  T +   P  T T +PT +    +
Sbjct: 4079 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTT 4135

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP------- 2296
            +T+    TP  T +  T P  ++ + T   T   T+ PT+  ++ T+ VT  P       
Sbjct: 4136 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4195

Query: 2297 -------TSPVTNLTTRHPGP------TLSPTTRFLTSSLTAHGSTPASAPVSSLGTP-T 2342
                   T+P+  LTT +P P      T   T+  LT S T   + P +  ++S   P T
Sbjct: 4196 GPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255

Query: 2343 PTSPGVCS 2350
            PT+P   S
Sbjct: 4256 PTAPTTTS 4263



 Score =  454 bits (1169), Expect = e-127
 Identities = 397/1250 (31%), Positives = 568/1250 (45%), Gaps = 152/1250 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 1932 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 1990

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 1991 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2047

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2048 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2102

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2103 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2157

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2158 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2216

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2217 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2274

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2275 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2334

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2335 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2394

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2395 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2453

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2454 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2513

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2514 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2573

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2574 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2631

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2632 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2687

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2688 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2807

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2808 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2862

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 2863 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 2918

Query: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186
            ++ +  P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T 
Sbjct: 2919 VTPT--PTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2975

Query: 2187 -PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
             PTT  ++ +     +P  + T   T     ++P T       +T TV+PTP+     + 
Sbjct: 2976 TPTTTPITTTTTVTPTPTPTGTQTPT-----TTPIT-------TTTTVTPTPTPTGTQTP 3023

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
               P T  TT +    P  +   TT+  T+ TT  PT       +G     T+P+T  TT
Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTT 3079

Query: 2306 RHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
              P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3080 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3129



 Score =  454 bits (1169), Expect = e-127
 Identities = 397/1250 (31%), Positives = 568/1250 (45%), Gaps = 152/1250 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2013

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2014 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2070

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2125

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2126 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2180

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2181 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2239

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2240 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2297

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2298 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2357

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2418 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2476

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2536

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2537 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2596

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2597 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2654

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2655 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2710

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2711 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2770

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2771 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2830

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2831 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2885

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 2941

Query: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186
            ++ +  P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T 
Sbjct: 2942 VTPT--PTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2998

Query: 2187 -PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
             PTT  ++ +     +P  + T   T     ++P T       +T TV+PTP+     + 
Sbjct: 2999 TPTTTPITTTTTVTPTPTPTGTQTPT-----TTPIT-------TTTTVTPTPTPTGTQTP 3046

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
               P T  TT +    P  +   TT+  T+ TT  PT       +G     T+P+T  TT
Sbjct: 3047 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTT 3102

Query: 2306 RHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
              P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3152



 Score =  454 bits (1169), Expect = e-127
 Identities = 397/1250 (31%), Positives = 568/1250 (45%), Gaps = 152/1250 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2036

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2037 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2093

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2148

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2149 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2203

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2204 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2262

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2263 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2320

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2321 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2380

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2381 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2499

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2559

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2677

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2678 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2733

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2734 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2793

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2794 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2853

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2908

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 2964

Query: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186
            ++ +  P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T 
Sbjct: 2965 VTPT--PTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3021

Query: 2187 -PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
             PTT  ++ +     +P  + T   T     ++P T       +T TV+PTP+     + 
Sbjct: 3022 TPTTTPITTTTTVTPTPTPTGTQTPT-----TTPIT-------TTTTVTPTPTPTGTQTP 3069

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
               P T  TT +    P  +   TT+  T+ TT  PT       +G     T+P+T  TT
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTT 3125

Query: 2306 RHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
              P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3126 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3175



 Score =  454 bits (1169), Expect = e-127
 Identities = 397/1250 (31%), Positives = 568/1250 (45%), Gaps = 152/1250 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2059

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2116

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2171

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2172 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2226

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2227 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2285

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2286 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2343

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2344 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2403

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2404 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2522

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2523 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2582

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2642

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2643 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2700

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2701 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2756

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2816

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2877 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2931

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 2932 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 2987

Query: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186
            ++ +  P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T 
Sbjct: 2988 VTPT--PTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3044

Query: 2187 -PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
             PTT  ++ +     +P  + T   T     ++P T       +T TV+PTP+     + 
Sbjct: 3045 TPTTTPITTTTTVTPTPTPTGTQTPT-----TTPIT-------TTTTVTPTPTPTGTQTP 3092

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
               P T  TT +    P  +   TT+  T+ TT  PT       +G     T+P+T  TT
Sbjct: 3093 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTT 3148

Query: 2306 RHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
              P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3149 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198



 Score =  454 bits (1169), Expect = e-127
 Identities = 397/1250 (31%), Positives = 568/1250 (45%), Gaps = 152/1250 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2024 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2082

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2083 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2139

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2140 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2194

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2195 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2249

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2250 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2308

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2309 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2366

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2367 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2426

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2427 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2486

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2487 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2545

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2546 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2605

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2606 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2665

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2666 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2723

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2724 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2779

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2780 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2839

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2840 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2899

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 3010

Query: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186
            ++ +  P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T 
Sbjct: 3011 VTPT--PTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3067

Query: 2187 -PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
             PTT  ++ +     +P  + T   T     ++P T       +T TV+PTP+     + 
Sbjct: 3068 TPTTTPITTTTTVTPTPTPTGTQTPT-----TTPIT-------TTTTVTPTPTPTGTQTP 3115

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
               P T  TT +    P  +   TT+  T+ TT  PT       +G     T+P+T  TT
Sbjct: 3116 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTT 3171

Query: 2306 RHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
              P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3172 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3221



 Score =  454 bits (1169), Expect = e-127
 Identities = 397/1250 (31%), Positives = 568/1250 (45%), Gaps = 152/1250 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2047 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2105

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2106 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2162

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2217

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2218 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2272

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2273 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2331

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2332 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2389

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2390 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2449

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2450 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2509

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2510 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2568

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2569 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2628

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2629 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2688

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2746

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2747 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2802

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2803 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2862

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2863 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2922

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2977

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 2978 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 3033

Query: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186
            ++ +  P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T 
Sbjct: 3034 VTPT--PTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3090

Query: 2187 -PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
             PTT  ++ +     +P  + T   T     ++P T       +T TV+PTP+     + 
Sbjct: 3091 TPTTTPITTTTTVTPTPTPTGTQTPT-----TTPIT-------TTTTVTPTPTPTGTQTP 3138

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
               P T  TT +    P  +   TT+  T+ TT  PT       +G     T+P+T  TT
Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTT 3194

Query: 2306 RHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
              P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3195 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3244



 Score =  454 bits (1169), Expect = e-127
 Identities = 397/1250 (31%), Positives = 568/1250 (45%), Gaps = 152/1250 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2070 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2128

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2129 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2185

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2186 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2240

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2241 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2295

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2296 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2354

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2355 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2412

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2413 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2472

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2473 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2532

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2533 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2591

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2651

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2652 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2711

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2712 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2769

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2770 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2825

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2826 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2885

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2945

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2946 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3000

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 3056

Query: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186
            ++ +  P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T 
Sbjct: 3057 VTPT--PTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3113

Query: 2187 -PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
             PTT  ++ +     +P  + T   T     ++P T       +T TV+PTP+     + 
Sbjct: 3114 TPTTTPITTTTTVTPTPTPTGTQTPT-----TTPIT-------TTTTVTPTPTPTGTQTP 3161

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
               P T  TT +    P  +   TT+  T+ TT  PT       +G     T+P+T  TT
Sbjct: 3162 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTT 3217

Query: 2306 RHPGP----TLSPTTRFLTSSLTAHGS-------TPASAPVSSLGTPTPT 2344
              P P    T +PTT  +T++ T   +       TP + P+++  T TPT
Sbjct: 3218 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3267



 Score =  452 bits (1162), Expect = e-126
 Identities = 401/1280 (31%), Positives = 579/1280 (45%), Gaps = 166/1280 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2151

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2152 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2208

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2263

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2264 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2318

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2319 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2377

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2378 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2435

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2436 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2495

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2496 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2556 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2614

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2674

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2675 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2734

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2735 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2792

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2793 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2848

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2849 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2908

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2968

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3023

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 3079

Query: 2127 LSSSFSPS-----PSAPSTVSSYV-----PSSHSSPQTS----------SPSVGTSSSFV 2166
            ++ + +P+      + P T ++ V     P+   +P T+          +P+   + +  
Sbjct: 3080 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3139

Query: 2167 SAPVHSTTLSSGSHSSLSTH-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSA 2224
            + P+ +TT  + + +   T  PTT  + + + + P+     T    T P T ++  T + 
Sbjct: 3140 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT- 3198

Query: 2225 LLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSG 2284
              P  T T +PT +    ++T+    TP  T +  T P  ++ + T   T   T+ PT+ 
Sbjct: 3199 --PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3256

Query: 2285 FVSLTSGVTGIP---------TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS--- 2328
             ++ T+ VT  P         T+P+T  TT  P P    T +PTT  +T++ T   +   
Sbjct: 3257 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3316

Query: 2329 ----TPASAPVSSLGTPTPT 2344
                TP + P+++  T TPT
Sbjct: 3317 TGTQTPTTTPITTTTTVTPT 3336



 Score =  452 bits (1162), Expect = e-126
 Identities = 401/1280 (31%), Positives = 579/1280 (45%), Gaps = 166/1280 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2174

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2175 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2231

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2232 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2286

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2341

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2342 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2400

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2401 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2458

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2459 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2518

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2519 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2578

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2637

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2697

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2698 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2757

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2815

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2816 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2871

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2872 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2931

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2932 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2991

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 2992 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3046

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 3047 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 3102

Query: 2127 LSSSFSPS-----PSAPSTVSSYV-----PSSHSSPQTS----------SPSVGTSSSFV 2166
            ++ + +P+      + P T ++ V     P+   +P T+          +P+   + +  
Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162

Query: 2167 SAPVHSTTLSSGSHSSLSTH-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSA 2224
            + P+ +TT  + + +   T  PTT  + + + + P+     T    T P T ++  T + 
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT- 3221

Query: 2225 LLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSG 2284
              P  T T +PT +    ++T+    TP  T +  T P  ++ + T   T   T+ PT+ 
Sbjct: 3222 --PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279

Query: 2285 FVSLTSGVTGIP---------TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS--- 2328
             ++ T+ VT  P         T+P+T  TT  P P    T +PTT  +T++ T   +   
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3339

Query: 2329 ----TPASAPVSSLGTPTPT 2344
                TP + P+++  T TPT
Sbjct: 3340 TGTQTPTTTPITTTTTVTPT 3359



 Score =  452 bits (1162), Expect = e-126
 Identities = 401/1280 (31%), Positives = 579/1280 (45%), Gaps = 166/1280 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 2139 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 2197

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 2198 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 2254

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 2309

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 2310 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 2364

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 2365 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2423

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 2424 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2481

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 2482 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2541

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASIHSMP 1649
                   TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ ++   P
Sbjct: 2542 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2601

Query: 1650 TGT-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            T T    PTT   T +T   PT T T + T    + + T  T T   + T +        
Sbjct: 2602 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPI 2660

Query: 1709 TSTTNITPNPTSTGTP-----PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
            T+TT +TP PT TGT      P+T TT+ T     + +   T+T + + T+ T  P  T 
Sbjct: 2661 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2720

Query: 1764 T---------STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            T         +TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++T  
Sbjct: 2721 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2780

Query: 1815 VTATSFQT-------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPS-----THTVI 1856
            VT T   T             TT  PTP+   T  PT  P  +T+ VTP+     T T  
Sbjct: 2781 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2838

Query: 1857 IPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
             PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T+
Sbjct: 2839 -PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTTT 2894

Query: 1916 TSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHSP 1971
            T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +P
Sbjct: 2895 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954

Query: 1972 PTGS-----------SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 2020
             T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP+
Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3014

Query: 2021 ---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MTV 2066
                     T T I TT T   T      TPTGT  P TT   T +T T  P      T 
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069

Query: 2067 TTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ 2126
            TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT  
Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 3125

Query: 2127 LSSSFSPS-----PSAPSTVSSYV-----PSSHSSPQTS----------SPSVGTSSSFV 2166
            ++ + +P+      + P T ++ V     P+   +P T+          +P+   + +  
Sbjct: 3126 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3185

Query: 2167 SAPVHSTTLSSGSHSSLSTH-PTTASV-SASPLFPSSPAASTTIRATLPHTISSPFTLSA 2224
            + P+ +TT  + + +   T  PTT  + + + + P+     T    T P T ++  T + 
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT- 3244

Query: 2225 LLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSG 2284
              P  T T +PT +    ++T+    TP  T +  T P  ++ + T   T   T+ PT+ 
Sbjct: 3245 --PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3302

Query: 2285 FVSLTSGVTGIP---------TSPVTNLTTRHPGP----TLSPTTRFLTSSLTAHGS--- 2328
             ++ T+ VT  P         T+P+T  TT  P P    T +PTT  +T++ T   +   
Sbjct: 3303 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3362

Query: 2329 ----TPASAPVSSLGTPTPT 2344
                TP + P+++  T TPT
Sbjct: 3363 TGTQTPTTTPITTTTTVTPT 3382



 Score =  449 bits (1154), Expect = e-125
 Identities = 414/1272 (32%), Positives = 580/1272 (45%), Gaps = 169/1272 (13%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 3232

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3289

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3344

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3345 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3399

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3400 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3458

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3459 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3517 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3576

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3577 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3632

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3633 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3691

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3692 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3751

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3752 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3811

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3812 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3871

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3872 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3928

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3929 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3988

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3989 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4048

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 4049 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4103

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 4104 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 4159

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPS-VGTSSSFVSAPVHSTT-----LSSGS 2179
             ++   +P+P+   T ++  P + ++  T +P+  GT +     P H++T     L++ +
Sbjct: 4160 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQT---GPPTHTSTAPIAELTTSN 4213

Query: 2180 HSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPS- 2238
                S+ P T+  ++SPL       STT+ +TLP  I     +++  P ST T   T S 
Sbjct: 4214 PPPESSTPQTSRSTSSPL-----TESTTLLSTLPPAIE----MTSTAPPSTPTAPTTTSG 4264

Query: 2239 ----SHLASSTIAFPSTPR--TTASTHTAPAFSSQSTTSRSTSLTTRVPTS-GFVSLTSG 2291
                S   S+T + P TP   TT  + +AP  S+  TT+ S    T  P S   +  T+G
Sbjct: 4265 GHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTG 4324

Query: 2292 VTGIPTSP----VTNLTTRHPGP-----TLSPTTRFLTSSLT--------AHGSTPASAP 2334
            +   P+S     V N T   PG      T   T  F+  SL+        +  STP+  P
Sbjct: 4325 LRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTP 4384

Query: 2335 VSSLGTPTPTSP 2346
              S  TPTP+ P
Sbjct: 4385 TPSKSTPTPSKP 4396



 Score =  445 bits (1144), Expect = e-124
 Identities = 396/1240 (31%), Positives = 559/1240 (45%), Gaps = 145/1240 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 3186

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3243

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3298

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3299 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3353

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3354 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3412

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3413 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3470

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3471 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3530

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3586

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3587 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3645

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T + + T+ T  P
Sbjct: 3646 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3705

Query: 1760 EVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
              T          T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI+
Sbjct: 3706 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3765

Query: 1811 STGPVTATS-------------FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
            +T  VT T                TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
              PT T + T+ ++   PT T    PTT   T +T   P  TPT +GT Q+P++     T
Sbjct: 3826 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGT-QTPTTTPITTT 3882

Query: 1915 STSLPYHT-SSTHHPEVTP-TSTTNITPKHTSTGTRTPVAH--TTSASSSRLPTPFTTHS 1970
            +T  P  T + T  P  TP T+TT +TP  T TGT+TP     TT+ + +  PTP  T +
Sbjct: 3883 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3942

Query: 1971 PPT-----------GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 2019
            P T             +P  +  P T     TTT  PTP+   T  PT  P  +T+ VTP
Sbjct: 3943 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4002

Query: 2020 S---------THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPP-----MT 2065
            +         T T I TT T   T      TPTGT  P TT   T +T T  P      T
Sbjct: 4003 TPTPTGTQTPTTTPITTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4057

Query: 2066 VTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTN 2125
             TT+  + T +   T T + +   +++ +   ++  P  +P  TQ P     TTP++TT 
Sbjct: 4058 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTT 4113

Query: 2126 QLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
             ++   +P+P+   T ++  P + ++  T +P+   + +  + P+ +TT  + + +   T
Sbjct: 4114 TVTP--TPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4170

Query: 2186 H-PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASS 2244
              PTT  ++ +     +P  + T      HT ++P     +  ++T    P  S+   S 
Sbjct: 4171 QTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAP-----IAELTTSNPPPESSTPQTSR 4225

Query: 2245 TIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLT 2304
            + + P T  TT  +   PA    ST   ST  T    TSG         G   SP  + T
Sbjct: 4226 STSSPLTESTTLLSTLPPAIEMTSTAPPSTP-TAPTTTSG---------GHTLSPPPSTT 4275

Query: 2305 TRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPT 2344
            T  PG   +PT    T S +A   +      +S  TPTPT
Sbjct: 4276 TSPPG---TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312



 Score =  424 bits (1090), Expect = e-118
 Identities = 399/1291 (30%), Positives = 572/1291 (44%), Gaps = 179/1291 (13%)

Query: 1198 PPTTPQPPTTPQL---PTTGSRPTQVWPMTGTSTTIGLLSSTGPSPS-SNHTPASPTQTP 1253
            P TTP PPTT      PTT   P    P+T  ++T  L  +T PSP  +  T   PT TP
Sbjct: 1598 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1657

Query: 1254 LLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTA 1313
              P T T S P  ++  PP  TT  +P  T+  PPT T+  T   PT T ++   T +T 
Sbjct: 1658 SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTM--TTPSPTTTPSSP-ITTTTT 1714

Query: 1314 SPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQ--TTGPRP------- 1364
              +TT+   S   TTMT P+P    T+P+ P +T   LP TT +   TT P P       
Sbjct: 1715 PSSTTT--PSPPPTTMTTPSPT---TTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPT 1769

Query: 1365 -TPASTTGPTTP-------------------QPGQPTR-------PTATETTQTRTTTEY 1397
             +P STT PTTP                   +PG  T        P        R T   
Sbjct: 1770 FSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYP 1829

Query: 1398 TTP--QTPHTTHSPPTAG----SPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFS 1451
              P  Q   T     + G    +     G V   +F              T PT +   +
Sbjct: 1830 DVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTT 1889

Query: 1452 TSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQ 1511
            T   TP T T IT T     T+ +    PTGT  P TT   T +T T    TPT +GT  
Sbjct: 1890 TENPTPPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQT 1941

Query: 1512 AHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTTITPNPTSTRTRTPVAH--TNSATSSR 1568
              ++  T  T  +     + T  P  TP T+TTT+TP PT T T+TP     T + T + 
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2001

Query: 1569 PPPPFTTHSPPT-----------GSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVP 1617
             P P  T +P T             +P  +  P T     TTT  PTP+   T  PT  P
Sbjct: 2002 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061

Query: 1618 PFSTSLVTPS-THT-VITPTHAQMATSASIHSMPTGT-IPPPTTLKATGSTHTAPTMTLT 1674
              +T+ VTP+ T T   TPT   + T+ ++   PT T    PTT   T +T   PT T T
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2121

Query: 1675 TSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTG-----TPPMTVT 1729
             + T    + + T  T T   + T +        T+TT +TP PT TG     T P+T T
Sbjct: 2122 GTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2180

Query: 1730 TSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS---------TSTTSITPNHTSTGTRT 1780
            T+ T     + +   T+T + + T+ T  P  T          T+TT++TP  T TGT+T
Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240

Query: 1781 PVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATS-------------FQTTTTYP 1827
            P     + T++  PTP  T +    TTPI++T  VT T                TTT  P
Sbjct: 2241 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300

Query: 1828 TPSHPHTTLPTHVPSFSTSLVTPS-THT-VIIPTHTQMATSASIHSMPTGT-IPPPTTIK 1884
            TP+   T  PT  P  +T+ VTP+ T T    PT T + T+ ++   PT T    PTT  
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360

Query: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHT-SSTHHPEVTP-TSTTNITPKH 1942
             T +T   P  TPT +GT Q+P++     T+T  P  T + T  P  TP T+TT +TP  
Sbjct: 2361 ITTTTTVTP--TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417

Query: 1943 TSTGTRTPVAH--TTSASSSRLPTPFTTHSPPT-----------GSSPFSSTGPMTATSF 1989
            T TGT+TP     TT+ + +  PTP  T +P T             +P  +  P T    
Sbjct: 2418 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2477

Query: 1990 QTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS---------THTVIITTHTQMATSASIHS 2040
             TTT  PTP+   T  PT  P  +T+ VTP+         T T I TT T   T      
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-----P 2532

Query: 2041 TPTGTVPPPTTLKATGSTHTAPP-----MTVTTSGTSQTHSSFSTATASSSFISSSSWLP 2095
            TPTGT  P TT   T +T T  P      T TT+  + T +   T T + +   +++ + 
Sbjct: 2533 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2592

Query: 2096 QNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTS 2155
              ++  P  +P  TQ P     TTP++TT  ++   +P+P+   T ++  P + ++  T 
Sbjct: 2593 TTTTVTPTPTPTGTQTP----TTTPITTTTTVTP--TPTPTGTQTPTT-TPITTTTTVTP 2645

Query: 2156 SPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH-PTTASV-SASPLFPSSPAASTTIRATLP 2213
            +P+   + +  + P+ +TT  + + +   T  PTT  + + + + P+     T    T P
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705

Query: 2214 HTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRS 2273
             T ++  T +   P  T T +PT +    ++T+    TP  T +  T P  ++ + T   
Sbjct: 2706 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762

Query: 2274 TSLTTRVPTSGFVSLTSGVTGIP---------TSPVTNLTTRHPGP----TLSPTTRFLT 2320
            T   T+ PT+  ++ T+ VT  P         T+P+T  TT  P P    T +PTT  +T
Sbjct: 2763 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2822

Query: 2321 SSLTAHGS-------TPASAPVSSLGTPTPT 2344
            ++ T   +       TP + P+++  T TPT
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2853



 Score =  392 bits (1008), Expect = e-108
 Identities = 363/1114 (32%), Positives = 505/1114 (45%), Gaps = 138/1114 (12%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 3439

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3496

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3551

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3552 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3606

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3607 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3665

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3666 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3723

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3724 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3783

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3784 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 3839

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 3840 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 3898

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T +          
Sbjct: 3899 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI---------- 3948

Query: 1760 EVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATS 1819
                T+TT++TP  T TGT+TP     + T++  PTP  T +    TTPI++        
Sbjct: 3949 ----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-------- 3996

Query: 1820 FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPP 1879
              TTT  PTP+   T  PT  P  +T+ VTP+      PT             PTGT  P
Sbjct: 3997 --TTTVTPTPTPTGTQTPTTTPITTTTTVTPT------PT-------------PTGTQTP 4035

Query: 1880 PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHT-SSTHHPEVTP-TSTTN 1937
             TT   T +T T    TPT +GT Q+P++     T+T  P  T + T  P  TP T+TT 
Sbjct: 4036 TTTPITTTTTVTP---TPTPTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4091

Query: 1938 ITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPT 1997
            +TP  T TGT+TP     + +++  PTP      PTG+   ++T P+T T    TT  PT
Sbjct: 4092 VTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTT-PITTT----TTVTPT 4141

Query: 1998 PSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG- 2056
            P+   T  PT  P  +T+ VTP+       T TQ  T+  I +T T T  P  T   TG 
Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTVTPTPTPTGTQTGP 4197

Query: 2057 --STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHL 2114
               T TAP   +TTS      S+  T+ ++SS ++ S+ L    S+ PP+  +T+  P  
Sbjct: 4198 PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTL---LSTLPPAIEMTSTAPP- 4253

Query: 2115 SSATTPVSTT--NQLSSSFSPSPSAPST-VSSYVPSSHSSPQTSSPSVGTSSSFVSAPVH 2171
            S+ T P +T+  + LS   S + S P T        S S+P  S+    T+S++   P  
Sbjct: 4254 STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313

Query: 2172 STTLSSGSHSSLSTHPTTASV----SASPLFPSSPAASTTIRATLPH-TISSPFTLSALL 2226
             +T S    + L  +P++  +    + +   P     + T   T      S   TL    
Sbjct: 4314 LSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYN 4373

Query: 2227 PISTVTVSPTPSSHLASSTIAFPSTPRTTASTHT 2260
                 T SPTP+   ++ T   PS P +T S  T
Sbjct: 4374 WSCPSTPSPTPTPSKSTPT---PSKPSSTPSKPT 4404



 Score =  301 bits (771), Expect = 5e-81
 Identities = 286/892 (32%), Positives = 387/892 (43%), Gaps = 107/892 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 3646

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            TP+   T  +  PT +  + P  T   T   T+ + PT T   T T  T    TT     
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITT---TTTVTPTPTPTGTQTPTTTPITTTTTVTP 3703

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG 1371
            T +P  T T  +T  TT T  TP  + T    P +T    P TT T  T P PTP  T  
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----PITTTTTVT-PTPTPTGTQT 3758

Query: 1372 PTTPQPGQPTRPTATET---TQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFH 1428
            PTT      T  T T T   TQT TTT  TT  T   T +P   G+  P+T P+T T   
Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--VTPTPTPTGTQTPTTTPITTT--- 3813

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPS-THT-VITPTHAQMATSASNHSAPTGT-IP 1485
             TT  PTP+   T  PT  P  +T+ VTP+ T T   TPT   + T+ +    PT T   
Sbjct: 3814 -TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3872

Query: 1486 PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTP-TSTTT 1544
             PTT   T +T   P  TPT +GT    ++  T  T  +     + T  P  TP T+TTT
Sbjct: 3873 TPTTTPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3930

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT------ 1598
            +TP PT T T+TP     + T++  P P  T +    ++P ++T  +T T   T      
Sbjct: 3931 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3990

Query: 1599 -------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM--- 1648
                   TT  PTP+   T  PT  P  +T+ VTP+     TPT  Q  T+  I +    
Sbjct: 3991 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP----TPTGTQTPTTTPITTTTTV 4046

Query: 1649 -----PTGTIPPPTTLKATGSTHT-APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH 1702
                 PTGT  P TT   T +T T  PT T T + T+  +++  T  T T   + T +  
Sbjct: 4047 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPT 4105

Query: 1703 HAEATSTSTTNITPNPTSTGTP---PMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHP 1759
                T+T+T   TP PT T TP   P+T TT+ T     + +   T+T +          
Sbjct: 4106 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI---------- 4155

Query: 1760 EVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATS 1819
                T+TT++TP  T TGT+TP     + T++  PTP      PTGT     T   TA  
Sbjct: 4156 ----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTGPPTHTSTAPI 4206

Query: 1820 FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTG--TI 1877
             + TT+ P    P ++ P    S S+ L   +T    +P   +M TS +  S PT   T 
Sbjct: 4207 AELTTSNPP---PESSTPQTSRSTSSPLTESTTLLSTLPPAIEM-TSTAPPSTPTAPTTT 4262

Query: 1878 PPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTN 1937
                T+    ST T+PP TPT   T+ S    S+A T +++   T+S   P  TP ST +
Sbjct: 4263 SGGHTLSPPPSTTTSPPGTPTRGTTTGS----SSAPTPSTVQTTTTSAWTPTPTPLSTPS 4318

Query: 1938 ITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPT 1997
            I     +TG R   +         L   +        +  +  T      S   T  +  
Sbjct: 4319 II---RTTGLRPYPSSVLICCV--LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYN 4373

Query: 1998 PSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPT-GTVPP 2048
             S P T  PT  P  S S  TPS               +S  S PT GT PP
Sbjct: 4374 WSCPSTPSPTPTP--SKSTPTPS-------------KPSSTPSKPTPGTKPP 4410



 Score =  146 bits (369), Expect = 2e-34
 Identities = 159/554 (28%), Positives = 230/554 (41%), Gaps = 39/554 (7%)

Query: 1811 STGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSL-VTPSTHTV----IIPTHTQMAT 1865
            +T P T T+F T T   TP+   TT  T  P+ ST L  TP    +    I   H    +
Sbjct: 1259 TTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGS 1318

Query: 1866 SASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSL---PYHT 1922
                     G    P  I+          +           S     K        P+  
Sbjct: 1319 DDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQCDVSVGFICKNEDQFGNGPFGL 1378

Query: 1923 SSTHHPEVT---PTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFS 1979
               +   V    P      TP   +T    P   TT+     LP P TT SPPT ++   
Sbjct: 1379 CYDYKIRVNCCWPMDKCITTPSPPTTTPSPPPTSTTT-----LP-PTTTPSPPTTTT--- 1429

Query: 1980 STGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI--ITTHTQMATSAS 2037
            +T P T T     TT  TP  P TT P+  PP ST+   P T T     TT +   T+ S
Sbjct: 1430 TTPPPTTTPSPPITTTTTP--PPTTTPS--PPISTTTTPPPTTTPSPPTTTPSPPTTTPS 1485

Query: 2038 IHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQN 2097
              +T T T PP TT     +T   PP + TT   + T S  +T T +    ++ S  P  
Sbjct: 1486 PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPS-PPTT 1544

Query: 2098 SSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSP 2157
            +   PP+S  TT LP  ++ + P +TT     + +PSP   +T S    ++ + P T++P
Sbjct: 1545 TPITPPTS--TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602

Query: 2158 SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTIS 2217
            S  T+++    P   TT  S   ++  T PT+ +       PS P  +TT     P T  
Sbjct: 1603 SPPTTTTTTPPP---TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP--PTTTP 1657

Query: 2218 SPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLT 2277
            SP T +   P  T T +P P++  +S     PS P TT +T +     S   T+ +T  +
Sbjct: 1658 SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSS 1717

Query: 2278 TRVPTSGFVSLTS-GVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVS 2336
            T  P+    ++T+   T  P+ P T +TT  P  T SP T   T+ L    + P  +P S
Sbjct: 1718 TTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLT---TTPLPPSITPPTFSPFS 1774

Query: 2337 SLGTPTPTSPGVCS 2350
            +  TPT     +C+
Sbjct: 1775 TT-TPTTPCVPLCN 1787



 Score =  127 bits (319), Expect = 1e-28
 Identities = 127/429 (29%), Positives = 178/429 (41%), Gaps = 56/429 (13%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T+T I   ++  P+P+   T  +PT 
Sbjct: 4002 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTT 4060

Query: 1252 TPLLPATLTSSKPTASSGEPPRPT-----TAVTPQAT---SGLPPTATLRSTAT-----K 1298
            TP+   T  +  PT +  + P  T     T VTP  T   +  P T  + +T T      
Sbjct: 4061 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4120

Query: 1299 PTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTT-AT 1357
            PT TQ  T    +T +  T +   + T+T  T P   T+  +PT P  T  + P TT  T
Sbjct: 4121 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPIT 4179

Query: 1358 QTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVP 1417
             TT   PTP  T   T P     T P A E T +    E +TPQT  +T SP T  + + 
Sbjct: 4180 TTTTVTPTPTPTGTQTGPPTHTSTAPIA-ELTTSNPPPESSTPQTSRSTSSPLTESTTLL 4238

Query: 1418 STGPVTATSFHATTTYPTPSHPETTLPTHV--PPFSTSLVTPSTHTVIT-------PTHA 1468
            ST P  A    +T    TP+ P TT   H   PP ST+   P T T  T       PT +
Sbjct: 4239 STLP-PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPS 4297

Query: 1469 QMATSASNHSAPTGT-IPPPTTLKATG---------------STHTAP--PITPTTSGTS 1510
             + T+ ++   PT T +  P+ ++ TG                T+ AP   +   T G +
Sbjct: 4298 TVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDT 4357

Query: 1511 QAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPP 1570
                + S + T    +    ST  P  TP+ +T     P+ST ++         T    P
Sbjct: 4358 CYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSK--------PTPGTKP 4409

Query: 1571 PPFTTHSPP 1579
            P      PP
Sbjct: 4410 PECPDFDPP 4418



 Score =  107 bits (267), Expect = 1e-22
 Identities = 102/385 (26%), Positives = 164/385 (42%), Gaps = 53/385 (13%)

Query: 40  PDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSIS---- 95
           P  G C+  G  H +TFD   Y F G C Y+ A    D   ++++     P GS      
Sbjct: 386 PCPGTCALEGGSHITTFDGKTYTFHGDCYYVLAK--GDHNDSYALLGELAPCGSTDKQTC 443

Query: 96  -RIIVELGAS----VVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELEL 150
            + +V L       VV  S+  + + ++ V +LP+ +    +        +V+  + + L
Sbjct: 444 LKTVVLLADKKKNVVVFKSDGSVLLNELQV-NLPHVTASFSVFRPSSYHIMVSMAIGVRL 502

Query: 151 EVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-------KFLEPHKFAA- 202
           +V   P   L V +++   GQ+ GLCGNF+G   ++F +  G        F    K  + 
Sbjct: 503 QVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSS 562

Query: 203 ----LQKLDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAP--ECSVSKEP--FVLS 253
               L  LDDP   C      S ++  A +A   C+ L     P   C  + +P  +   
Sbjct: 563 CHDKLDWLDDP---C------SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKR 613

Query: 254 CQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCS--VGQCPANQVYQEC 311
           C+ D         ++  CA LS Y+R C+  G  +  WR   +C+  VG CP +QV+   
Sbjct: 614 CKYDTCNC--QNNEDCLCAALSSYARACTAKGVMLWGWRE-HVCNKDVGSCPNSQVFLYN 670

Query: 312 GSACVKTCSNPQHSCSSSC------TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAM 365
            + C +TC +   +  S C        GC CP+ T L++      CVP+ +C C   G  
Sbjct: 671 LTTCQQTCRSLSEA-DSHCLEGFAPVDGCGCPDHTFLDEKGR---CVPLAKCSCYHRGLY 726

Query: 366 YAPGEVTIAACQTCRCTLGRWVCTE 390
              G+V +   + C C  GR  C +
Sbjct: 727 LEAGDVVVRQEERCVCRDGRLHCRQ 751



 Score =  104 bits (260), Expect = 9e-22
 Identities = 120/507 (23%), Positives = 183/507 (36%), Gaps = 70/507 (13%)

Query: 388  CTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQ--SPQLPEDGALMAVYDKSGVS 445
            C    C  +C+  G     TFD   Y + G CTY+L++  SP +   G  +  Y      
Sbjct: 4472 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 4531

Query: 446  HSETSLVAVVYLSRQDKIV-----ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMA 500
                    +V    Q+ ++     +     V  N +A  LPYK   + V++    ++   
Sbjct: 4532 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 4591

Query: 501  TSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVD 560
               G  ++V    +  +      +F   T+G CG     T+DD     G          D
Sbjct: 4592 PELG--VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAAD 4649

Query: 561  SWRAG-----NCPAALERETDPC------SMSQLNKVCAETHCSMLLRTGTVFERCHATV 609
             W        +CP +      P         +  +K C  +    L++  ++F +CHA V
Sbjct: 4650 QWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIK-DSLFAQCHALV 4708

Query: 610  NPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDN-CTIPCTGNT 668
             P  +Y  CV+ +C +       CA+L  Y   C+ + + L  WR+     C + C  + 
Sbjct: 4709 PPQHYYDACVFDSC-FMPGSSLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHR 4766

Query: 669  TFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGY 728
             +     A E TC S S +     ++ V V+GC CP+GT     G  V    C C+  G 
Sbjct: 4767 EYQACGPAEEPTCKSSSSQ----QNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV--GP 4820

Query: 729  KFILAE--QSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
              +  E  +    +   C C+ G      +P             K CSQ    K    C 
Sbjct: 4821 DNVPREFGEHFEFDCKNCVCLEGGSGIICQP-------------KRCSQ----KPVTHCV 4863

Query: 787  PTCQMLATGVACVPTKCE-PGCVCAEGLYENADGQC----------VPPEECP---CEFS 832
                 LAT V    T C    C C   L +     C          VP   CP   CE  
Sbjct: 4864 EDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESK 4923

Query: 833  GVSYPGGAELH-------TDCRTCSCS 852
            GV   G AE         + C+ C C+
Sbjct: 4924 GVCVHGNAEYQPGSPVYSSKCQDCVCT 4950



 Score =  104 bits (259), Expect = 1e-21
 Identities = 104/373 (27%), Positives = 159/373 (42%), Gaps = 49/373 (13%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELG 102
            G CS +G+GH+ TFD   YDF G C+Y+       A   +  Q       SI    V  G
Sbjct: 858  GTCSIYGSGHYITFDGKYYDFDGHCSYV-------AVQDYCGQNSSLGSFSIITENVPCG 910

Query: 103  ASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSV----RLVAKQLELE----LEVVW 154
             + VT S+AI        + L      +     G  V    R V + L +E    + V+W
Sbjct: 911  TTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIW 970

Query: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEF-------VSEEGKFLEPHKFA-ALQKL 206
               + + + +   Y G +CGLCGNFD +  N+F       VS E  F    K A     +
Sbjct: 971  DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDV 1030

Query: 207  DDPGEICTFQDIPSTHVRQAQHARICTQLLTLVAPEC--SVSKEPFVLSCQADVAAAPQP 264
                E C+     + H R++   + C+ L + V   C   V  +PF  +C  D  +    
Sbjct: 1031 STNPEPCSL----NPH-RRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTG 1085

Query: 265  GPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSV--------GQCPANQVYQECGSACV 316
            G     C+ ++ Y+++C+  G  V  WR+P LC +         +C  +  Y+ CG+   
Sbjct: 1086 GDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWH--YEPCGNRSF 1142

Query: 317  KTCS--NPQHS-CSSSCTFGCF--CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGE- 370
            +TC   N  HS  S S   GC+  CP+   + +  +   CV   +C C +    Y PG  
Sbjct: 1143 ETCRTINGIHSNISVSYLEGCYPRCPKDRPIYE-EDLKKCVTADKCGCYVEDTHYPPGAS 1201

Query: 371  -VTIAACQTCRCT 382
              T   C++C CT
Sbjct: 1202 VPTEETCKSCVCT 1214



 Score =  101 bits (252), Expect = 8e-21
 Identities = 99/374 (26%), Positives = 150/374 (40%), Gaps = 53/374 (14%)

Query: 834  VSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYI 893
            +S  GG+EL T+ RT +            H  + C+ +G  H  TFDG  F F G C+Y 
Sbjct: 15   LSLAGGSELQTEGRTRN------------HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYN 62

Query: 894  LATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGL--SVVLADRNYTVTGEEP 951
             A+D  G      ++K    ++  G         ++  L  +    +   R+  V     
Sbjct: 63   FASDCRG------SYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAV 116

Query: 952  HVQLGVTPGALSLVVD--ISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNM 1009
                  +PG L    D    +  R  LTL+WNR   +++ +    ++  CGLCG++NG +
Sbjct: 117  VSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNG-L 175

Query: 1010 KDDFETRSRYVASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINS 1066
            +   E  S  V  S LE  N  K      +C D      P S +   R+  ER   ++ +
Sbjct: 176  QSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSE-HRAECER---LLTA 231

Query: 1067 QTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPA 1125
            + FA C   V   PY  AC +D C C  GGD  C+C  VA +++ C   G    +WRT  
Sbjct: 232  EAFADCQDLVPLEPYLRACQQDRCRC-PGGD-TCVCSTVAEFSRQCSHAGGRPGNWRTAT 289

Query: 1126 FCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQPQSVPG----SNIEGCYNCS 1181
             CP  C     + + G                 PC+       V        ++GC+   
Sbjct: 290  LCPKTCPGNLVYLESG----------------SPCMDTCSHLEVSSLCEEHRMDGCFCPE 333

Query: 1182 QDEYFDHEEGVCVP 1195
               Y D  +  CVP
Sbjct: 334  GTVYDDIGDSGCVP 347



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 115/491 (23%), Positives = 180/491 (36%), Gaps = 74/491 (15%)

Query: 770  FKSCSQSSENKF-GAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCV---PPE 825
            F +CS S   +F   +C  T     T     PT  +P    ++        +C    PP 
Sbjct: 4360 FVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPR 4419

Query: 826  E-------CPCEFSGVSYPGGAEL-HTDCRTC---SCSRGRW--------ACQQGTHCPS 866
            +       C C  +   Y    E+   +C      +CS G           C     C  
Sbjct: 4420 QENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDC 4479

Query: 867  TCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTCS 925
             CT +G+ H +TFDG  + + GNC Y+L  +   ++ S   F +  +N  C  N  V+C 
Sbjct: 4480 YCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE---ISPSVDNFGVYIDNYHCDPNDKVSCP 4536

Query: 926  RAI------------KIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVDISIPGR 973
            R +             + +  + V +      V        L V    ++ VVDI   G 
Sbjct: 4537 RTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELG- 4595

Query: 974  YNLTLIWNRHMTILIRIA-RASQDPLCGLCGNFNGNMKDDF-----ETRSRYVASSELEL 1027
                L+    ++  +R+      +   G CG       DD      E  S   A+++  L
Sbjct: 4596 ---VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWL 4652

Query: 1028 VNSWKESPLCGDVSFVTDPCSLNA--------FRRSWAERKCSVINSQTFATCHSKVYHL 1079
            VN     P C   S  T   ++           +       C +I    FA CH+ V   
Sbjct: 4653 VND-PSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQ 4711

Query: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWR--TPAFCPIYCGFYNTH 1137
             YY+ACV D+C    G   EC   ++ AYA  C  + +C+DWR  T   C + C  +  +
Sbjct: 4712 HYYDACVFDSCFM-PGSSLECA--SLQAYAALCAQQNICLDWRNHTHGACLVECPSHREY 4768

Query: 1138 TQDGHGE----YQYTQEANCTWHYQPCLCPSQPQS-VPGSN--IEGCYNCSQD----EYF 1186
               G  E       + + N T   + C CP    +  PG +  ++ C     D    E+ 
Sbjct: 4769 QACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFG 4828

Query: 1187 DHEEGVCVPCM 1197
            +H E  C  C+
Sbjct: 4829 EHFEFDCKNCV 4839



 Score = 89.0 bits (219), Expect = 5e-17
 Identities = 104/344 (30%), Positives = 133/344 (38%), Gaps = 61/344 (17%)

Query: 1191 GVCVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPT 1250
            G   P   P T     TP    TG++     P+T T+T      +  P+P+   T   PT
Sbjct: 4100 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQT---PT 4151

Query: 1251 QTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATA 1310
             TP+   T T+  PT      P PT   TP  T   P T T        TVT   T    
Sbjct: 4152 TTPI--TTTTTVTPT------PTPTGTQTPTTT---PITTT-------TTVTPTPTPTGT 4193

Query: 1311 STASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTT 1370
             T  P  TSTA     TT     P    ++P   +ST+  L  +T   +T P     ++T
Sbjct: 4194 QTGPPTHTSTAPIAELTT---SNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST 4250

Query: 1371 GPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGS---PVPSTGPVTATSF 1427
             P    P  PT PT T    T +    TT   P T     T GS   P PST   T TS 
Sbjct: 4251 AP----PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS- 4305

Query: 1428 HATTTYPTP-SHPETTLPTHVPPFSTSL----VTPSTH-----TVITPTHAQMATSAS-- 1475
             A T  PTP S P     T + P+ +S+    V   T+      V   T+       +  
Sbjct: 4306 -AWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS 4364

Query: 1476 --------NHSAPTGTIPPPTTLKATGSTHTAPPITPT--TSGT 1509
                    N S P+   P PT  K+T  T + P  TP+  T GT
Sbjct: 4365 LSCTLEFYNWSCPSTPSPTPTPSKST-PTPSKPSSTPSKPTPGT 4407



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 104/409 (25%), Positives = 162/409 (39%), Gaps = 64/409 (15%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRR---GPDGSIS---RII 98
            C+ WG  H+ TFD   Y + G C Y+       +   F V +      P+  +S    +I
Sbjct: 4481 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 4540

Query: 99   VELGASVVTVSEAIISVKDIGV------ISLPYTSNGLQITPFGQSVRLVAKQLELELEV 152
            V      V +    +    + V      ++LPY   GL++  +   +  V    EL + V
Sbjct: 4541 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEV--YQSGINYVVDIPELGVLV 4598

Query: 153  VWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKL-DDPGE 211
             +   S  + L   ++     G CG      +++ +   G+ +   + AA Q L +DP +
Sbjct: 4599 SYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSK 4658

Query: 212  -ICTFQDIPSTHVRQAQHA---------RICTQLLTLVAPECSVSKEPFVLSCQADVA-- 259
              C      ST  R A            + CT      +P C + K+     C A V   
Sbjct: 4659 PHCPHSS--STTKRPAVTVPGGGKTTPHKDCTP-----SPLCQLIKDSLFAQCHALVPPQ 4711

Query: 260  ---------AAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWR--SPGLCSVGQCPANQVY 308
                     +   PG  +  CA+L  Y+  C+     +  WR  + G C V +CP+++ Y
Sbjct: 4712 HYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICL-DWRNHTHGACLV-ECPSHREY 4768

Query: 309  QECGSACVKTC-SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
            Q CG A   TC S+     ++    GCFCPEGT +N       CV    C CV  G    
Sbjct: 4769 QACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGT-MNYAPGFDVCVKT--CGCV--GPDNV 4823

Query: 368  P---GEVTIAACQTCRCTLG--RWVCTERPCP----GHCSLEGGSFVTT 407
            P   GE     C+ C C  G    +C  + C      HC +E G+++ T
Sbjct: 4824 PREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHC-VEDGTYLAT 4871



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 70/253 (27%), Positives = 98/253 (38%), Gaps = 45/253 (17%)

Query: 1198 PPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTT-IGLLSSTGPSPSSNHTPAS-PTQTPLL 1255
            P TTP   TT   PT     TQ  P T TST  I  L+++ P P S+    S  T +PL 
Sbjct: 4173 PTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT 4232

Query: 1256 PAT--LTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKP--TVTQATTRATAS 1311
             +T  L++  P         P+T   P  TSG    +   ST T P  T T+ TT  ++S
Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSS 4292

Query: 1312 TASPAT--TSTAQSTTRTTMTLPTPA---TSGTSPTLPKST-------------NQELPG 1353
              +P+T  T+T  + T T   L TP+   T+G  P  P S               +E+  
Sbjct: 4293 APTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRP-YPSSVLICCVLNDTYYAPGEEVYN 4351

Query: 1354 TTATQT--------------------TGPRPTPASTTGPTTPQPGQPTRPTATETTQTRT 1393
             T   T                    + P PTP  +    TP     T    T  T+   
Sbjct: 4352 GTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPE 4411

Query: 1394 TTEYTTPQTPHTT 1406
              ++  P+  + T
Sbjct: 4412 CPDFDPPRQENET 4424



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 2340 TPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPL 2399
            TP   +   CS      E+++ GC   V +  C G+C +   ++   Q +D  CSCC+  
Sbjct: 5066 TPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEE 5125

Query: 2400 HSYEQQLELPCPDPSTPGRRLVLTLQVFSHCVCSSVACG 2438
             + ++++ L CP+    G  L  T      C C    CG
Sbjct: 5126 KTSQREVVLSCPN----GGSLTHTYTHIESCQCQDTVCG 5160


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 1009 bits (2608), Expect = 0.0
 Identities = 745/2340 (31%), Positives = 1045/2340 (44%), Gaps = 313/2340 (13%)

Query: 12   GALLSAGLANTSYTSPGLQRLKDSPQTAPDKGQ-CSTWGAGHFSTFDHHVYDFSGTCNYI 70
            GA  S+     S+  P       SP      G+ CSTWG  H+ TFD  V+ F G CNY+
Sbjct: 43   GAPTSSPTRRVSFVPPVTVFPSLSPLNPAHNGRVCSTWGDFHYKTFDGDVFRFPGLCNYV 102

Query: 71   FAATCKDAFPTFSVQLRRGPDGS---ISRIIVELGASVVTVSEAIISVKDIGVISLPYTS 127
            F+  C+ A+  F+VQLRRG  GS   ++R++++    V+  S   + +       LPY+ 
Sbjct: 103  FSEHCRAAYEDFNVQLRRGLVGSRPVVTRVVIKAQGLVLEASNGSVLINGQRE-ELPYSR 161

Query: 128  NGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDG-KVTNE 186
             GL +   G  +++    + L L  +W  +   ++ ++ KY  Q CGLCG+F+G    NE
Sbjct: 162  TGLLVEQSGDYIKV---SIRLVLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNE 218

Query: 187  FVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPSTHVRQAQHARICTQLLTLVAP---EC 243
            F +   + L P +F  LQKLD P E C    +P           IC +  TL+ P   EC
Sbjct: 219  FYAHNAR-LTPLQFGNLQKLDGPTEQCP-DPLPLPAGNCTDEEGICHR--TLLGPAFAEC 274

Query: 244  S--VSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQ 301
               V    ++ +C  D+   P        CAT  EYSRQC+  G   R WR P LC    
Sbjct: 275  HALVDSTAYLAACAQDLCRCP-----TCPCATFVEYSRQCAHAGGQPRNWRCPELCP-RT 328

Query: 302  CPANQVYQECGSACVKTCSNPQHS--CSSSCTFGCFCPEG---TVLNDLSNNHTCVPVTQ 356
            CP N  +QECGS C  TCSNPQ +  C   C  GCFCP G   TVL+D++++  C+P+ Q
Sbjct: 329  CPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDGCFCPPGRSCTVLDDITHSG-CLPLGQ 387

Query: 357  CPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFH 416
            CPC   G  Y+PG      C +C C+ G W C + PCPG CS++GG+ ++T+D + Y  H
Sbjct: 388  CPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQDLPCPGTCSVQGGAHISTYDEKLYDLH 447

Query: 417  GTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVY-LSRQDKIV-ISQDEVVTNN 474
            G C+Y+L +         ++A   K G++ +E  L AV   L   D  + +  D  V  N
Sbjct: 448  GDCSYVLSKKCA-DSSFTVLAELRKCGLTDNENCLKAVTLSLDGGDTAIRVQADGGVFLN 506

Query: 475  GEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCG 534
                 LP    NIT+F  +S  + + T  GL+L+VQL P+ Q +V + P  +GQ  GLCG
Sbjct: 507  SIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLLVQLVPLMQVFVRLDPAHQGQMCGLCG 566

Query: 535  NFNGDTTDDFTTSMGIAEGTASLFVDSWRA-GNCPAALERETDPCSMSQLNKVCAETHCS 593
            NFN +  DDFT   G+ E T + F ++W+A   C  A     DPCS+S  N+  A   CS
Sbjct: 567  NFNQNQADDFTALSGVVEATGAAFANTWKAQAACANARNSFEDPCSLSVENENYARHWCS 626

Query: 594  MLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGW 653
             L    + F RCH+ +NP PF+  C++  CN E +   +CAAL  YVHAC+ +GV L  W
Sbjct: 627  RLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCERSEDCLCAALSSYVHACAAKGVQLSDW 686

Query: 654  RSSVDNCTI---PCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLN 710
            R  V  CT     C  +  ++Y   AC+ TC  LS+    C  S VPVDGC CP GT+LN
Sbjct: 687  RDGV--CTKYMQNCPKSQRYAYVVDACQPTCRGLSEADVTCSVSFVPVDGCTCPAGTFLN 744

Query: 711  QKGECVRKAQCPCILEGYKFILAEQSTVIN-GITCHCINGRLSCPQRPQMFLASCQAPKT 769
              G CV   +CPC   G   +LA    V + G  C C  G+LSC          C AP  
Sbjct: 745  DAGACVPAQECPCYAHGT--VLAPGEVVHDEGAVCSCTGGKLSCLGASLQKSTGCAAPMV 802

Query: 770  FKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPC 829
            +  CS SS    GA C  +C  L  G  C  T C  GCVC  GL  +  G C+  E+CPC
Sbjct: 803  YLDCSNSSAGTPGAECLRSCHTLDVG--CFSTHCVSGCVCPPGLVSDGSGGCIAEEDCPC 860

Query: 830  EFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGN 889
              +  +Y  G  +  DC TC+C   RW C     C  TC  YG+GH ITFDG R+ F+G+
Sbjct: 861  VHNEATYKPGETIRVDCNTCTCRNRRWECSHRL-CLGTCVAYGDGHFITFDGDRYSFEGS 919

Query: 890  CEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGE 949
            CEYILA D CG N +  TF+I+TEN+ CG +G TCS+AIK+F+    ++L +  +     
Sbjct: 920  CEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVESYELILQEGTFKAVAR 979

Query: 950  EPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNM 1009
             P    G  P  +  +    +   + + + W+R  ++ IR+ +  +  +CGLCGNF+ N 
Sbjct: 980  GPG---GDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNA 1036

Query: 1010 KDDFETRSRYVASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTF 1069
             +DF TRSR V    LE  NSWK SP C D     DPC+ N FR+SWA+++CS+++  TF
Sbjct: 1037 INDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTF 1096

Query: 1070 ATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPI 1129
            A C S+V    YYEACV DAC CDSGGDCEC C AVAAYAQAC D G+CV WRTP  CP+
Sbjct: 1097 AACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPL 1156

Query: 1130 YCGFYNTHTQDGHGEYQYTQEANCTWHYQP---------------CLC---------PSQ 1165
            +C FYN H               C WHYQP               CL          P  
Sbjct: 1157 FCDFYNPH-------------GGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKC 1203

Query: 1166 PQSVPGSNIE--------GCYNCSQDEYFDHEEGVCVP---------CMPPTTPQPPTTP 1208
            P S P  N +        GCY+     Y+D   G  VP         C P       +  
Sbjct: 1204 PPSQPFFNEDQMKCVAQCGCYD-KDGNYYD--VGARVPTAENCQSCNCTPSGIQCAHSLE 1260

Query: 1209 QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHT--------PASPTQTPLLPATLT 1260
                T    T  +     +TT GL +       SN T        P +P  TP    T T
Sbjct: 1261 ACTCTYEDRTYSYQDVIYNTTDGLGACLIAICGSNGTIIRKAVACPGTPATTPF---TFT 1317

Query: 1261 SSKPTASSGEPPRPTTAVTPQAT-------SGLPPTATL-------------RSTATKPT 1300
            ++    S+  P  P + V  +         +G  P   L             R     P 
Sbjct: 1318 TAWVPHSTTSPALPVSTVCVREVCRWSSWYNGHRPEPGLGGGDFETFENLRQRGYQVCPV 1377

Query: 1301 VTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTN------QELP-G 1353
            +     RA      P      Q      M     A S  SP L           + +P G
Sbjct: 1378 LADIECRAAQLPDMPLE-ELGQQVDCDRMRGLMCANSQQSPPLCHDYELRVLCCEYVPCG 1436

Query: 1354 TTATQTTGPRPTPASTTGPTTPQPGQPT-------------RPTATETTQTRTTTE--YT 1398
             +    T P+P+ +++T P  P P Q T             R TA  T+QT +++     
Sbjct: 1437 PSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSGPVTV 1496

Query: 1399 TPQTPHTTHSPPTA----------------GSPVPSTGPVTATSFHATTT-----YPTPS 1437
            TP  P TT   P                  G  V S   + A   H             S
Sbjct: 1497 TPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIECQAES 1556

Query: 1438 HPETTLP---------THVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPT 1488
             P  TL           H      +        +      ++   + +H     T PPPT
Sbjct: 1557 FPNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPT 1616

Query: 1489 TLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPN 1548
            T   T +T T   +  T   TS    + +   + T++ + +     P  T T  T  T  
Sbjct: 1617 TELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGG 1676

Query: 1549 PTSTRTRTPVAHTNSATSSRP-------------------PPPF------TTHSPPTGSS 1583
            PT+    T       ATS+ P                   PP        T+ + PTG++
Sbjct: 1677 PTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTA 1736

Query: 1584 PFSSTGPMTATSFKTTTTYPTPSHPQTTLP---THVPPFSTSLVTPST------------ 1628
              +S  P+T +   T T+  + S  +T+ P   T + P + +  +  T            
Sbjct: 1737 STASKEPLTTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEW 1796

Query: 1629 HTVITPTH----AQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTM----TLTTSGTSQ 1680
              V  PT       M T  +I +        P +++     +   ++     + T     
Sbjct: 1797 FDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLET 1856

Query: 1681 ALSSLNTAKTSTSLHSHTSSTH------HAEATSTSTTNITPNPTSTG------TPPMT- 1727
             L+  N  +T         +        ++   ST  T+ T  P+ST       T P T 
Sbjct: 1857 GLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTT 1916

Query: 1728 -VTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTT 1786
              TT+ T  + +  ST +T+      T++   P VTS+  T    +   T T  P   +T
Sbjct: 1917 ATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKAT--PSSSPGTATALPALRST 1974

Query: 1787 SAT-SSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFST 1845
            + T ++   TP  + S  T  T +S T   TAT   T T   TP   HT+      + +T
Sbjct: 1975 ATTPTATSVTPIPSSSLGTTWTRLSQTTTPTAT-MSTATPSSTPETAHTSTVLTATATTT 2033

Query: 1846 ----SLVTPST-----HTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMT 1896
                S+ TPS+     HT  +PT T    +A+  S P   + PP  I  T         T
Sbjct: 2034 GATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTT--------TT 2085

Query: 1897 PTTSGTSQSPSSF------STAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTR-T 1949
            PTT G++ +PSS       +T  T+T+    T S   P  + T T+   P  T+T T  T
Sbjct: 2086 PTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPS-SSTQTSGTPPSLTTTATTIT 2144

Query: 1950 PVAHTTSASSSRLPTPFTTHSPP----TGSSPFSSTGPMTATS-FQTTTTYPTPSHPQTT 2004
                TT+ SS    TP TT  PP    T ++P +++  +T +S   TT T P P+   TT
Sbjct: 2145 ATGSTTNPSS----TPGTTPIPPVLTTTATTPAATSNTVTPSSALGTTHTPPVPNTMATT 2200

Query: 2005 LPTHVPPFS-----------TSLVTPSTHTV---IITTHTQMATSASI-HSTPTGTVPPP 2049
                +PP S           TS +  +TH      +T+HT  AT+ +  HSTP  + P P
Sbjct: 2201 HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHP 2260

Query: 2050 TTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT 2109
            ++      T  +PP   TT+    T +S +TATA+ S   +S+ LP    S P S+PITT
Sbjct: 2261 SS-----RTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLP----SSPTSAPITT 2311



 Score =  321 bits (822), Expect = 6e-87
 Identities = 393/1393 (28%), Positives = 568/1393 (40%), Gaps = 252/1393 (18%)

Query: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPA--------SPTQTP 1253
            P  P T    T  S P   W +T  +TT     STG + + + TP         S T T 
Sbjct: 3675 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 3734

Query: 1254 LLP--ATLTSSKPTASSGEPPRPTTAVTPQATSGL------PPTAT----LRSTATKPTV 1301
             +P  +T T+S   A++G P   TTA TP  TS        P TAT    LRSTAT PT 
Sbjct: 3735 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTA 3794

Query: 1302 TQ-------------------ATTRATASTASPATT----------STAQSTTRTTMTLP 1332
            T                     T  AT STA+P++T          +T  +TTR T ++ 
Sbjct: 3795 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVA 3854

Query: 1333 TPA-TSGTSPT--LPKSTN-------QELPGTTATQTTGPRPTPASTTGPTTPQPGQPTR 1382
            TP+ T GT+ T  +P +T           PGT  T       T   TT  +T  P     
Sbjct: 3855 TPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 3914

Query: 1383 PTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYP------TP 1436
             T T T  T TTT   T      + S  T+G+P       T  +   +TT P      TP
Sbjct: 3915 TTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTP 3974

Query: 1437 SHPETTLPTHVPPFSTSLVTPS-----THTVITP-----THAQMATSASNH-------SA 1479
              P  T     P  ++S VTPS     THT   P     TH +  + +S H       SA
Sbjct: 3975 IPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSA 4034

Query: 1480 PTGTIPPP-TTLKATGSTHTAPPITPTTSGTSQA----HSSFSTNKTP----------TS 1524
             +GT+     T  +TG++HT    T TT  ++ A    H S  T ++P          T+
Sbjct: 4035 TSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTT 4094

Query: 1525 LHSHTSSTHHPEVTPTST---TTITPNPTSTRTRT----PVAHTNSATSSRPPP-----P 1572
              S T++T  P  T TST   ++ T  P +T   T      A +     S P P      
Sbjct: 4095 ATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGD 4154

Query: 1573 FTTHS-----------PPTGSS---------PFSSTGPMTATS---------------FK 1597
            F T+S            P G           P    G +   S               FK
Sbjct: 4155 FDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFK 4214

Query: 1598 TTTTYP-------------TPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSAS 1644
                Y              TP+   T +P+  P  +T ++T  T T  T   A   ++A+
Sbjct: 4215 MCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPG-TTWILTELTTTATTT--ASTGSTAT 4271

Query: 1645 IHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHA 1704
              S P GT PPP  L +  +T TA         TS   +S ++ +T+T+L   TS+    
Sbjct: 4272 PSSTP-GTAPPPKVLTSPATTPTA---------TSSKATSSSSPRTATTLPVLTST---- 4317

Query: 1705 EATSTSTTNITPNPTST----GTPPMTVTTSGTSQSR----SSFSTAKTSTSLHSHTSST 1756
             AT ++ T++TP P+ST    GT P   TT   + S     S+  T  TST L +  ++T
Sbjct: 4318 -ATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTT 4376

Query: 1757 HHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVT 1816
                 +STST S TP  T   T    A TT+A +    TP +T       T +++T   T
Sbjct: 4377 R--ATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTT 4434

Query: 1817 ATSFQTTTTYPTP------SHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIH 1870
            A++  T T   TP      + P TT    VP+ ST+  + +  T   P  +  AT+ ++ 
Sbjct: 4435 ASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVT 4494

Query: 1871 SM---PTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHH 1927
            S    P+ +    T + A  ST T P  T  T+  S S  +  T  + T+ P  T ST  
Sbjct: 4495 SSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT 4554

Query: 1928 PEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTAT 1987
            P  TP  T + +   T+T T T    + +  SS   T  TT  P T ++ F++T    ++
Sbjct: 4555 PSSTP-ETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTAT---PSS 4610

Query: 1988 SFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVP 2047
            S  T  T P      TT  T  P  S S VTPS+  +  TTHT    + +  +  TG++ 
Sbjct: 4611 SPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSS--IPGTTHTARVLTTTTTTVATGSMA 4668

Query: 2048 PPTTLKATGSTH---TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPS 2104
             P++   T  T    T    T+T +G++   SS    T  +  ++S++  P  +SS+  S
Sbjct: 4669 TPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATS 4728

Query: 2105 SP---ITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT 2161
            S      T LP L+S  T  + T     SF+P PS+    +  VP+  ++P ++  ++ T
Sbjct: 4729 SSSPRTATTLPVLTSTATKSTAT-----SFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHT 4783

Query: 2162 SS-------SFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPH 2214
            SS       S V     + T ++ S ++ S+   T  +       ++  A+T   ATL  
Sbjct: 4784 SSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSS 4843

Query: 2215 TISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRST 2274
            T  + + L+    I+TV V PT S+  ASST+    TP+   +  T P  ++ +  S ST
Sbjct: 4844 TPGTTWILTEPSTIATVMV-PTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSST 4902

Query: 2275 SLTTRVPT--------------SGFVSLTSGVTGIPTSPV-TNLTTRHPGPTLSPTTRFL 2319
              TTR P               S  V  T   TG P+S   T    R  G   SP     
Sbjct: 4903 VGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIY 4962

Query: 2320 TSSLTA-----------------HGSTPASAP-VSSLGTPTPTSPGVCSVREQQEEITFK 2361
              +  A                  G+ P S P VSS    +P+    C       ++   
Sbjct: 4963 NKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNET 5022

Query: 2362 GCMANVTVTRCEG 2374
              + N TV RC G
Sbjct: 5023 WTLENCTVARCVG 5035



 Score =  311 bits (797), Expect = 5e-84
 Identities = 370/1238 (29%), Positives = 528/1238 (42%), Gaps = 155/1238 (12%)

Query: 1199 PTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPA--------SPT 1250
            P+TP   +T    T  S P   W +T  +TT     STG + + + TP         S T
Sbjct: 3675 PSTPATSST---ATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTT 3731

Query: 1251 QTPLLP--ATLTSSKPTASSGEPPRPTTAVTPQATS------GLPPTAT----LRSTATK 1298
             T  +P  +T T+S   A++G P   TTA TP  TS        P TAT    LRSTAT 
Sbjct: 3732 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATT 3791

Query: 1299 PTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQ 1358
            PT T  T  A  S++   T +    TT  T T+ T   S T  T   ST      TT T+
Sbjct: 3792 PTATSFT--AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATT-TR 3848

Query: 1359 TTGPRPTPASTTG-------PTTPQPGQPTRPT-------------ATETTQTRTTTEYT 1398
             TG   TP+ST G       PTT   G    P+             +T TT T + +  T
Sbjct: 3849 ATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVT 3908

Query: 1399 TPQTPHTTHSPP--TAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVT 1456
                P TTH+P   T  +   +TG + AT   +T T  TP    TT  T     ST+   
Sbjct: 3909 PSSVPGTTHTPTVLTTTTTTVATGSM-ATPSSSTQTSGTPPSLITTATTITATGSTT--N 3965

Query: 1457 PSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHT--APPITPTTSGTSQAHS 1514
            PS+    TP    + T+A+  +A + T+ P + L   G+THT   P  T TT G S + S
Sbjct: 3966 PSSTPGTTPIPPVLTTTATTPAATSSTVTPSSAL---GTTHTPPVPNTTATTHGRSLSPS 4022

Query: 1515 SFSTNKTP-TSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPF 1573
            S  T +T  TS  S T  T H    P++ T+ TP  T+  T+    H+  A SS  P   
Sbjct: 4023 SPHTVRTAWTSATSGTLGTTH-ITEPSTGTSHTPAATTGTTQ----HSTPALSSPHPSSR 4077

Query: 1574 TTHSPPTGSSPFSST-GPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI 1632
            TT SPP   SP ++T G  TATS  T T  P+ +   T LP      S+    P T  V 
Sbjct: 4078 TTESPP---SPGTTTPGHTTATSRTTATATPSKTRTSTLLP------SSPTSAPITTVVT 4128

Query: 1633 TPTHAQMATSASI---HSMP---TGTIPPPTTLKATGSTHTAPTMTLTTSGTSQ------ 1680
            T    Q A S  +   + MP    G     + ++A G       + L     +Q      
Sbjct: 4129 TGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLG 4188

Query: 1681 --------ALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSG 1732
                    +L      +    +       ++            P+  +T +  M  +T G
Sbjct: 4189 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPG 4248

Query: 1733 TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSR 1792
            T+   +  +T  T+T   + T ST  P  +ST  T+  P   ++   TP A ++ ATSS 
Sbjct: 4249 TTWILTELTTTATTT---ASTGSTATP--SSTPGTAPPPKVLTSPATTPTATSSKATSSS 4303

Query: 1793 LPTPFTTHSPPTGT---TPISSTGPVTATSFQTTTTYP-TPSHPHTTLPTHVPSFSTSLV 1848
             P   TT    T T   +  +S  P+ +++  TT T P   + P  T+ T  PS +    
Sbjct: 4304 SPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETT 4363

Query: 1849 TPSTHTVIIPTHTQMATSASIHSMPTGT--IPPPTTIKATGSTHTAPPMTP-TTSGTSQS 1905
              ST      T T+  +S S  S   GT  I    T  AT +  T P  TP +T GT+  
Sbjct: 4364 HTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWI 4423

Query: 1906 PSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSR---- 1961
             +  +T  T+T+    T ST  P  TP +T  +T   T+     P   T +ASS++    
Sbjct: 4424 LTELTTTATTTA---STGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAG 4480

Query: 1962 LPTPFTTHSPPTGSS----PFSSTGPMTA-TSFQTTTTYPTPSHPQTTLPTHVPPFSTSL 2016
             P   TT + PT +S    P SS G  TA  + ++T T PT      T  T +P  S+SL
Sbjct: 4481 TPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPT-----ATSFTAIP--SSSL 4533

Query: 2017 VTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQT-H 2075
             T  T     TT T   ++A+  STP  TV   T L AT +T  A     T S T  T H
Sbjct: 4534 GTTWTRLSQTTTPTATMSTATPSSTPE-TVHTSTVLTATATTTGATGSVATPSSTPGTAH 4592

Query: 2076 SSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLP--HLSSATTPVSTTNQLSSSFSP 2133
            ++    T ++ F           ++ P SSP T   P   +S+ TTP +TT        P
Sbjct: 4593 TTKVPTTTTTGF-----------TATPSSSPGTALTPPVWISTTTTPTTTT--------P 4633

Query: 2134 SPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
            + S  +   S +P +  + +  + +  T ++   A   S+T +SG+  SL+T  TT + +
Sbjct: 4634 TTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITAT 4693

Query: 2194 ASPLFPSSPAASTTIRATLPHTISSPFTLSALLPIS----TVTVSPTPSSHLASST-IAF 2248
             S   PSS   +T I   L  T ++P   S+    S    T T  P  +S    ST  +F
Sbjct: 4694 GSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSF 4753

Query: 2249 PSTPRTTA-STHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRH 2307
               P +T  +T T PA ++   ++ ST  T+  P +   S     T   T    +  T  
Sbjct: 4754 TPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTAT-- 4811

Query: 2308 PGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
            P  TL  TTR LT   T   +T A+   ++L +   T+
Sbjct: 4812 PSSTLG-TTRILTELTTTATTTAATGSTATLSSTPGTT 4848



 Score =  295 bits (756), Expect = 3e-79
 Identities = 385/1271 (30%), Positives = 530/1271 (41%), Gaps = 206/1271 (16%)

Query: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPA--------SPTQTP 1253
            P  P T       S P   W +T  +TT     STG + + + TP         S T T 
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 2477

Query: 1254 LLP--ATLTSSKPTASSGEPPRPTTAVTPQATSGL------PPTAT----LRSTATKPTV 1301
             +P  +T T+S   A++G P   TTA TP  TS        P TAT    LRSTAT PT 
Sbjct: 2478 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTA 2537

Query: 1302 TQAT-----------TRATASTASPATTSTA-----QSTTRTTMTLPTPATSGTSPTLPK 1345
            T  T           TR + +T   AT STA       T  T+  L T AT+ T  T   
Sbjct: 2538 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATT-TGATGSV 2596

Query: 1346 STNQELPGTT------ATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYT- 1398
            +T    PGT        T TTG   TP+S+ G         T P    TT T TT   T 
Sbjct: 2597 ATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTAR------TLPVWISTTTTPTTRGSTV 2650

Query: 1399 TPQT-PHTTHSPP--TAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLV 1455
            TP + P TTH+P   T  +   +TG + AT   +T T  TP    TT  T     ST+  
Sbjct: 2651 TPSSIPGTTHTPTVLTTTTTTVATGSM-ATPSSSTQTSGTPPSLTTTATTITATGSTT-- 2707

Query: 1456 TPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHT--APPITPTTSGTSQAH 1513
             PS+    TP    + T+A+  +A + T+ P + L   G+THT   P  T TT G S + 
Sbjct: 2708 NPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSAL---GTTHTPPVPNTTATTHGRSLSP 2764

Query: 1514 SSFSTNKTP-TSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPP 1572
            SS  T +T  TS  S T  T H    P++ T+ TP  T+  T+    H+  A SS  P  
Sbjct: 2765 SSPHTVRTAWTSATSGTLGTTH-ITEPSTGTSHTPAATTGTTQ----HSTPALSSPHPSS 2819

Query: 1573 FTTHSPPTGSSPFSST-GPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST--- 1628
             TT SPP   SP ++T G   ATS  T T  P+ +   T LP+   P S  + T  T   
Sbjct: 2820 RTTESPP---SPGTTTPGHTRATSRTTATATPSKTRTSTLLPS--SPTSAPITTVVTMGC 2874

Query: 1629 -------------HTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTT 1675
                         + +  P+     T ++I +        P  L+        P + L  
Sbjct: 2875 EPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQ--PGVPLRE 2932

Query: 1676 SGTSQALS-----------SLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTST-GT 1723
             G     S            +   K   +        ++    ST  T+ T  P+ST GT
Sbjct: 2933 LGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGT 2992

Query: 1724 PPMTVTTSGTSQSRSSFSTAKT-STSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPV 1782
                 T   T Q+ ++ +TA T ST++ S T  T  P    TST +           TP 
Sbjct: 2993 -----TWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTAT-----------TPT 3036

Query: 1783 AHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPS 1842
            A ++ ATSS  P   TT    T T   S     TATSF                 T +PS
Sbjct: 3037 ATSSKATSSSSPRTATTLPVLTSTATKS-----TATSF-----------------TPIPS 3074

Query: 1843 FSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTI---KATGSTHTAPPMTP-T 1898
            F+      +T T+   T T MAT ++IH   T      +T+   KAT +  T+   TP +
Sbjct: 3075 FTLG----TTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSS 3130

Query: 1899 TSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSAS 1958
            T GT+   +  +TA T+T+    T  T  P  TP +T  +T   T+     P   T +AS
Sbjct: 3131 TPGTTWILTELTTAATTTAA---TGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS 3187

Query: 1959 SSR-----LPTPFTTHSPPT--GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPP 2011
            S+R     L    +T + PT   S    S+ P TAT+     +  T + P  T  T +P 
Sbjct: 3188 STRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRS--TATTPTATSVTAIP- 3244

Query: 2012 FSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGT 2071
             S+SL T  T     TT T   ++A+  STP  TV   T L  T +T  A     T S T
Sbjct: 3245 -SSSLGTAWTRLSQTTTPTATMSTATPSSTPE-TVHTSTVLTTTTTTTRATGSVATPSST 3302

Query: 2072 SQT-HSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSS 2130
              T H++    T ++ F           ++ P SSP T   P +  +TT   TT    S+
Sbjct: 3303 PGTAHTTKVPTTTTTGF-----------TATPSSSPGTALTPPVWISTTTTPTTR--GST 3349

Query: 2131 FSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTA 2190
             +PS S P T  +    + ++   ++ S+ T S        S+T +SG+  SL+T  TT 
Sbjct: 3350 VTPS-SIPGTTHTATVLTTTTTTVATGSMATPS--------SSTQTSGTPPSLTTTATTI 3400

Query: 2191 SVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPS 2250
            + + S   PSS   +T I   L  T ++P   S     STV    TPSS  A  T   P 
Sbjct: 3401 TATGSTTNPSSTPGTTPIPPVLTTTATTPAATS-----STV----TPSS--ALGTTHTPP 3449

Query: 2251 TPRTTASTH--TAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHP 2308
             P TTA+TH  + P  S  +  +  TS T+ +  +  ++  S VT   T   T  TT+H 
Sbjct: 3450 VPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS-HTPAATTSTTQHS 3508

Query: 2309 GPTLS---PTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVREQQEEITFKGCMA 2365
             P LS   P++R   S  +   +TP     +S  T T T P                 + 
Sbjct: 3509 TPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATAT-PSKTRTSTLLPSSPTSAPIT 3567

Query: 2366 NVTVTRCEGAC 2376
             V  T CE  C
Sbjct: 3568 TVVTTGCEPQC 3578



 Score =  289 bits (739), Expect = 3e-77
 Identities = 336/1208 (27%), Positives = 507/1208 (41%), Gaps = 163/1208 (13%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPL 1254
            P    +T  P +TP+   T    T +     T+   G +++   +P + HT   PT T  
Sbjct: 3818 PTATMSTATPSSTPE---TAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTT 3874

Query: 1255 LPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTAS 1314
                  SS P  +   P   +T  TP  +      +++  T   PTV   TT  T +T S
Sbjct: 3875 GFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVL-TTTTTTVATGS 3933

Query: 1315 PATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTT 1374
             AT S++  T+ T  +L T AT+ T+                   TG    P+ST G TT
Sbjct: 3934 MATPSSSTQTSGTPPSLITTATTITA-------------------TGSTTNPSSTPG-TT 3973

Query: 1375 PQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYP 1434
            P P  P   T T TT   T++  T      TTH+P     PVP+T   TAT+ H  +  P
Sbjct: 3974 PIP--PVL-TTTATTPAATSSTVTPSSALGTTHTP-----PVPNT---TATT-HGRSLSP 4021

Query: 1435 TPSHPETTLPTHVPP---FSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLK 1491
            +  H   T  T        +T +  PST T  TP      T  + HS P  + P P    
Sbjct: 4022 SSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA---ATTGTTQHSTPALSSPHP---- 4074

Query: 1492 ATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTIT----- 1546
            ++ +T + P    TT G + A S  +   TP+   + T     P   P +T   T     
Sbjct: 4075 SSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQ 4134

Query: 1547 ---------------PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPM 1591
                           P+     T + +     A   + P      +      P    G +
Sbjct: 4135 CAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ-PLGLECRAQAQPGVPLGELGQV 4193

Query: 1592 TATS---------------FKTTTTYP----------TPSHPQTTLPTHVP---PFSTSL 1623
               S               FK    Y            PS P T+  T +P   P +T +
Sbjct: 4194 VECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS-STAMPSSTPGTTWI 4252

Query: 1624 VTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALS 1683
            +T  T T  T   A   ++A+  S P GT PPP  L +  +T TA         TS   +
Sbjct: 4253 LTELTTTATTT--ASTGSTATPSSTP-GTAPPPKVLTSPATTPTA---------TSSKAT 4300

Query: 1684 SLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS----TGTPP----MTVTTSGTSQ 1735
            S ++ +T+T+L   TS+     AT ++ T++TP P+S    TGT P      V T  T  
Sbjct: 4301 SSSSPRTATTLPVLTST-----ATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIH 4355

Query: 1736 SRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
              S+  T  TST L +  ++T     +STST S TP  T   T    A TT+A +    T
Sbjct: 4356 PSSTPETTHTSTVLTTKATTTR--ATSSTSTPSSTPGTTWILTELTTAATTTAATGPTAT 4413

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTP------SHPHTTLPTHVPSFSTSLVT 1849
            P +T       T +++T   TA++  T T   TP      + P TT    VP+ ST+  +
Sbjct: 4414 PSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS 4473

Query: 1850 PSTHTVIIPTHTQMATSASIHS---MPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSP 1906
             +  T   P  +  AT+ ++ S    P+ +    T + A  ST T P  T  T+  S S 
Sbjct: 4474 STQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSL 4533

Query: 1907 SSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPF 1966
             +  T  + T+ P  T ST  P  TP  T + +   T+T T T    + +  SS   T  
Sbjct: 4534 GTTWTRLSQTTTPTATMSTATPSSTP-ETVHTSTVLTATATTTGATGSVATPSSTPGTAH 4592

Query: 1967 TTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVII 2026
            TT  P T ++ F++T    ++S  T  T P      TT  T  P  S S VTPS  ++  
Sbjct: 4593 TTKVPTTTTTGFTAT---PSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPS--SIPG 4647

Query: 2027 TTHTQMATSASIHSTPTGTVPPPTTLKATGSTH---TAPPMTVTTSGTSQTHSSFSTATA 2083
            TTHT    + +  +  TG++  P++   T  T    T    T+T +G++   SS    T 
Sbjct: 4648 TTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTP 4707

Query: 2084 SSSFISSSSWLPQNSSSRPPSSP---ITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPST 2140
             +  ++S++  P  +SS+  SS      T LP L+S  T  + T     SF+P PS+   
Sbjct: 4708 ITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTAT-----SFTPIPSSTLW 4762

Query: 2141 VSSYVPSSHSSPQTSSPSVGTSS-------SFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
             +  VP+  ++P ++  ++ TSS       S V     + T ++ S ++ S+   T  + 
Sbjct: 4763 TTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRIL 4822

Query: 2194 ASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPR 2253
                  ++  A+T   ATL  T  + + L+    I+TV V PT S+  ASST+    TP+
Sbjct: 4823 TELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMV-PTGSTATASSTLGTAHTPK 4881

Query: 2254 TTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSL-TSGVTGIPTSPVTNLTTRHPGPTL 2312
               +  T P  ++ +  S ST  TTR P     SL T  V+ + +S +T L      PT 
Sbjct: 4882 VVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLR-----PTG 4936

Query: 2313 SPTTRFLT 2320
             P++ F T
Sbjct: 4937 FPSSHFST 4944



 Score =  277 bits (708), Expect = 1e-73
 Identities = 354/1244 (28%), Positives = 497/1244 (39%), Gaps = 152/1244 (12%)

Query: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPS--PSSNHTPASP----TQTPLL 1255
            P  P T    T  S P   W +T  +T     ++TG +  PSS    A P    T T   
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATT 3034

Query: 1256 PATLTSSKPTASSGE------PPRPTTAVTPQATSGLP-PTATLRSTATKPTVTQATTRA 1308
            P T TSSK T+SS        P   +TA    ATS  P P+ TL +T T P  T  T  A
Sbjct: 3035 P-TATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQT-TTPMA 3092

Query: 1309 TASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGT-----------TAT 1357
            T ST  P++T     TT T+  L T AT+ T  T   ST    PGT           T T
Sbjct: 3093 TMSTIHPSST---PETTHTSTVLTTKATT-TRATSSMSTPSSTPGTTWILTELTTAATTT 3148

Query: 1358 QTTGPRPTPASTTGPT--TPQPGQP---TRPTATETTQTRTTTEYTTPQTPHTTHSPPT- 1411
              TGP  TP+ST G T    +P      T PT +  T + T     T +   +T + PT 
Sbjct: 3149 AATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTV 3208

Query: 1412 -AGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1470
             +    PS+ P TAT+  A  +  T + P  T  T +P  S+SL T  T    T T    
Sbjct: 3209 ISSRATPSSSPGTATALPALRS--TATTPTATSVTAIP--SSSLGTAWTRLSQTTT---- 3260

Query: 1471 ATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHS--- 1527
                     PT T+   T      + HT+  +T TT+ T    S  + + TP + H+   
Sbjct: 3261 ---------PTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKV 3311

Query: 1528 HTSSTHHPEVTPTST--TTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPF 1585
             T++T     TP+S+  T +TP    + T TP    ++ T S  P    T +  T ++  
Sbjct: 3312 PTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTT 3371

Query: 1586 SSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASI 1645
             +TG M AT   +T T  TP    TT  T     ST+   PS+    TP    + T+A+ 
Sbjct: 3372 VATGSM-ATPSSSTQTSGTPPSLTTTATTITATGSTT--NPSSTPGTTPIPPVLTTTATT 3428

Query: 1646 HSMPTGTIPPPTTLKATGSTHT--APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHH 1703
             +  + T+ P + L   G+THT   P  T TT G S   SS +T +T     + TS+T  
Sbjct: 3429 PAATSSTVTPSSAL---GTTHTPPVPNTTATTHGRSLPPSSPHTVRT-----AWTSAT-- 3478

Query: 1704 AEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
              +    TT+IT   T T   P   TTS T  S  + S      S H  + +T  P    
Sbjct: 3479 --SGILGTTHITEPSTVTSHTP-AATTSTTQHSTPALS------SPHPSSRTTESPPSPG 3529

Query: 1764 TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTT 1823
            T+    TP HT   +RT    T S T +    P +  S P  T   +   P  A S    
Sbjct: 3530 TT----TPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLD 3585

Query: 1824 TTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTG-----TIP 1878
             +YP P        T+                        A   ++   P G        
Sbjct: 3586 YSYPMPGPSGGDFDTY--------------------SNIRAAGGAVCEQPLGLECRAQAQ 3625

Query: 1879 PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTN- 1937
            P   ++  G                +    F          +  +  H P    TS+T  
Sbjct: 3626 PGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAT 3685

Query: 1938 ---------ITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATS 1988
                     I  K T+T T T    +T+  SS   T +    P T ++    TG  TAT+
Sbjct: 3686 PSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG-STATA 3744

Query: 1989 FQTTTTYPTPSHPQT-TLPTHVPPFSTSLVTPSTHTVI----ITTHTQMATS-ASIHSTP 2042
              T  T  TP    T T PT     +T   +P T T +     T  T  ATS  +I S+ 
Sbjct: 3745 SSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSS 3804

Query: 2043 TGT----VPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS 2098
             GT    +   TT  AT ST T P  T  T+ TS   ++ +T T ++  +++ S  P  +
Sbjct: 3805 LGTTWTRLSQTTTPTATMSTAT-PSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTA 3863

Query: 2099 SSRPPSSPITTQLPHLSSATTPVSTTNQ--LSSSFSPSPSAPSTVSSYVPSSHSSPQTSS 2156
             +    +  TT      S++   + T    +S++ +P+ S  +   S VP +  +P   +
Sbjct: 3864 HTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLT 3923

Query: 2157 PSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTI 2216
             +  T ++   A   S+T +SG+  SL T  TT + + S   PSS   +T I   L  T 
Sbjct: 3924 TTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTA 3983

Query: 2217 SSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSL 2276
            ++P   S     STV    TPSS  A  T   P  P TTA+TH      S   T R+   
Sbjct: 3984 TTPAATS-----STV----TPSS--ALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWT 4032

Query: 2277 TTRVPTSGFVSLTSGVTGIPTSP-VTNLTTRHPGPTLS---PTTRFLTSSLTAHGSTPAS 2332
            +    T G   +T   TG   +P  T  TT+H  P LS   P++R   S  +   +TP  
Sbjct: 4033 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 4092

Query: 2333 APVSSLGTPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGAC 2376
               +S  T T T P                 +  V  T CE  C
Sbjct: 4093 TTATSRTTATAT-PSKTRTSTLLPSSPTSAPITTVVTTGCEPQC 4135



 Score =  267 bits (682), Expect = 1e-70
 Identities = 360/1287 (27%), Positives = 511/1287 (39%), Gaps = 196/1287 (15%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTS-TTIGLLSSTGPSPSSNHTPASPTQTPLLPAT 1258
            TT     TP      +R   VW  T T+ TT G   +    P + HTP   T T    AT
Sbjct: 2615 TTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVAT 2674

Query: 1259 ---LTSSKPTASSGEPPR-PTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTAS 1314
                T S  T +SG PP   TTA T  AT      ++   T   P V   T    A+T+S
Sbjct: 2675 GSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSS 2734

Query: 1315 PATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTT 1374
              T S+A  TT T    P P T+ T  T  +S +   P T  T  T        TT  T 
Sbjct: 2735 TVTPSSALGTTHTP---PVPNTTAT--THGRSLSPSSPHTVRTAWTSATSGTLGTTHITE 2789

Query: 1375 PQPGQPTRPTATETTQTRTTTEYTTPQ-TPHTTHSPPTAGSPVPSTGPVTATSFHATTTY 1433
            P  G    P AT  T   +T   ++P  +  TT SPP+ G+  P  G   ATS    T  
Sbjct: 2790 PSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP--GHTRATSRTTATAT 2847

Query: 1434 PTPSHPETTLPTHVPPFSTSLVTPST----------------HTVITPTHAQMATSASNH 1477
            P+ +   T LP+   P S  + T  T                + +  P+     T ++  
Sbjct: 2848 PSKTRTSTLLPSS--PTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 2905

Query: 1478 SAPTGTIPPPTTLKATGSTHTAPPITPTTSGT--SQAHSSFSTNKTPTSL---------- 1525
            +A       P  L+         P+         S        N+               
Sbjct: 2906 AAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 2965

Query: 1526 -----HSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTH--SP 1578
                 + H  ST  P  + T+T + TP  T   T    A T +AT+     P +T   +P
Sbjct: 2966 VFCCNYGHCPST--PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAP 3023

Query: 1579 PTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQ 1638
            P      ++T P TATS K T++    S P+T       P  TS  T ST T  TP    
Sbjct: 3024 PPKVLTSTATTP-TATSSKATSS----SSPRTATTL---PVLTSTATKSTATSFTPI--- 3072

Query: 1639 MATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHT 1698
                 S     TGT+P  TT      +   P+ T  T+ TS  L++  T   +TS  S  
Sbjct: 3073 ----PSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTP 3128

Query: 1699 SSTH---------HAEATSTSTTNITPNPTST-GT------PPMTVT-TSGTSQSRSSFS 1741
            SST             AT+T+ T  T  P+ST GT      P  T T T  T  + ++ S
Sbjct: 3129 SSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASS 3188

Query: 1742 TAKTSTSLHSHTSSTHHPEV-TSTSTTSITPNHTSTGTRTPVAHTTSAT-SSRLPTPFTT 1799
            T  T+ +L   TS+   P V +S +T S +P    T T  P   +T+ T ++   T   +
Sbjct: 3189 TRATAGTLKVLTSTATTPTVISSRATPSSSP---GTATALPALRSTATTPTATSVTAIPS 3245

Query: 1800 HSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHT----TLPTHVPSFSTSLVTPST--- 1852
             S  T  T +S T   TAT   T T   TP   HT    T  T     + S+ TPS+   
Sbjct: 3246 SSLGTAWTRLSQTTTPTAT-MSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPG 3304

Query: 1853 --HTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSF- 1909
              HT  +PT T    +A+  S P   + PP  I  T         TPTT G++ +PSS  
Sbjct: 3305 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTT--------TTPTTRGSTVTPSSIP 3356

Query: 1910 -----STAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTR-TPVAHTTSASSSRLP 1963
                 +T  T+T+    T S   P  + T T+   P  T+T T  T    TT+ SS    
Sbjct: 3357 GTTHTATVLTTTTTTVATGSMATPS-SSTQTSGTPPSLTTTATTITATGSTTNPSS---- 3411

Query: 1964 TPFTTHSPP----TGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTH---VPPFS--- 2013
            TP TT  PP    T ++P +++  +T +S   TT   TP  P TT  TH   +PP S   
Sbjct: 3412 TPGTTPIPPVLTTTATTPAATSSTVTPSSALGTT--HTPPVPNTTATTHGRSLPPSSPHT 3469

Query: 2014 --------TSLVTPSTHTV---IITTHTQMA-TSASIHSTPTGTVPPPTTLKATGSTHTA 2061
                    TS +  +TH      +T+HT  A TS + HSTP  + P P++      T  +
Sbjct: 3470 VRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSS-----RTTES 3524

Query: 2062 PPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT------------ 2109
            PP   TT+      +S +TATA+ S   +S+ LP + +S P ++ +TT            
Sbjct: 3525 PPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWL 3584

Query: 2110 --QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQ-------------- 2153
                P    +     T + + ++       P  +     +    P               
Sbjct: 3585 DYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFG 3644

Query: 2154 ---TSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASP-----LFPSSPAAS 2205
                +   VG      +  +     + G   S     +TA+ S++P     L   +  A+
Sbjct: 3645 LVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTAT 3704

Query: 2206 TT----IRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTA 2261
            TT      AT   T  + + L+     +TVTV PT S+  ASST A   TP  + +  T 
Sbjct: 3705 TTESTGSTATPSSTPGTTWILTEPSTTATVTV-PTGSTATASSTQATAGTPHVSTTATTP 3763

Query: 2262 PAFSSQSTTSRSTSLTTRVPTSGFVSLT---SGVTGIPTSPVTNLTTRHPGPTLSPTTRF 2318
               SS++T   S    T +P     + T   +  T IP+S +    TR    T +PT   
Sbjct: 3764 TVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTR-LSQTTTPTA-- 3820

Query: 2319 LTSSLTAHGSTPASAPVSSLGTPTPTS 2345
             T S     STP +A  S++ T T T+
Sbjct: 3821 -TMSTATPSSTPETAHTSTVLTTTATT 3846



 Score =  259 bits (663), Expect = 2e-68
 Identities = 369/1323 (27%), Positives = 529/1323 (39%), Gaps = 245/1323 (18%)

Query: 1201 TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGP--SPSSNHTPASPTQTPLLPAT 1258
            T  P  T    T  S P  V   T  +TT     +TG   +PSS    A  T+ P    T
Sbjct: 3258 TTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTT 3317

Query: 1259 LTSSKPTASSGE---PP-------RPTT---AVTPQATSGLPPTATLRSTATKPTVTQAT 1305
              ++ P++S G    PP        PTT    VTP +  G   TAT+ +T T    T + 
Sbjct: 3318 GFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSM 3377

Query: 1306 TRATASTAS----PATTSTAQSTTRTTMTLPTPATSGTSP---------TLPKSTNQELP 1352
               ++ST +    P+ T+TA + T T  T    +T GT+P         T P +T+  + 
Sbjct: 3378 ATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT 3437

Query: 1353 GTTATQTTGPRPTP---ASTTGPTTPQPGQPTRPTA-----------TETTQTRTTTEYT 1398
             ++A  TT   P P   A+T G + P     T  TA           T  T+  T T +T
Sbjct: 3438 PSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHT 3497

Query: 1399 TPQTPHTT-HSPPTAGSPVPST-------GPVTATSFHA-----TTTYPTPSHPETTLPT 1445
               T  TT HS P   SP PS+        P T T  H      TT   TPS   T+  T
Sbjct: 3498 PAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTS--T 3555

Query: 1446 HVPPFSTSLVTPSTHTVITPTHAQMATSA-SNHSAPT-----GTIPPPTTLKATGSTHTA 1499
             +P   TS   P T  V T    Q A S   ++S P      G     + ++A G     
Sbjct: 3556 LLPSSPTS--APITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCE 3613

Query: 1500 PPITPTTSGTSQA----------------HSSFSTNKTPTS---------LHSHTSSTHH 1534
             P+       +Q                       N+             +     +  H
Sbjct: 3614 QPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH 3673

Query: 1535 PEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTAT 1594
               TP +++T TP+ T   T      T +AT        TT S  TGS         TAT
Sbjct: 3674 CPSTPATSSTATPSSTPGTTWILTKLTTTAT--------TTES--TGS---------TAT 3714

Query: 1595 SFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIP 1654
               T  T    + P TT    VP  ST+  + +  T  TP  +  AT+ ++ S       
Sbjct: 3715 PSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFS 3774

Query: 1655 PP---TTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTST 1711
             P   T L A  ST T PT T  T+  S +L +  T  + T+  + T ST    AT +ST
Sbjct: 3775 SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMST----ATPSST 3830

Query: 1712 TNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITP 1771
                  P +  T  +  TT+ T+++  S +T  +ST   +HT  T  P  T+T  T +TP
Sbjct: 3831 ------PETAHTSTVLTTTATTTRATGSVAT-PSSTPGTAHT--TKVPTTTTTGFT-VTP 3880

Query: 1772 NHTSTGTRTP---VAHTTSATSS-----RLPTPFTTHSPP--TGTTPISSTGPVTATSFQ 1821
            + +    RTP   ++ TT+ T+S         P TTH+P   T TT   +TG + AT   
Sbjct: 3881 SSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSM-ATPSS 3939

Query: 1822 TTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPT 1881
            +T T  TP    TT  T   + ST+   PS+     P    + T+A+  +  + T+ P +
Sbjct: 3940 STQTSGTPPSLITTATTITATGSTT--NPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS 3997

Query: 1882 TIKATGSTHT--APPMTPTTSGTSQSPSSFSTAKTS-TSLPYHTSSTHHPEVTPTSTTNI 1938
               A G+THT   P  T TT G S SPSS  T +T+ TS    T  T H     T T+  
Sbjct: 3998 ---ALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS-- 4052

Query: 1939 TPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST-GPMTATSFQTTTTYPT 1997
               HT   T     H+T A SS  P+  TT SPP   SP ++T G  TATS  T T  P+
Sbjct: 4053 ---HTPAATTGTTQHSTPALSSPHPSSRTTESPP---SPGTTTPGHTTATSRTTATATPS 4106

Query: 1998 PSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP-------- 2049
             +   T LP        S  T +  T ++TT  +   + S     +  +P P        
Sbjct: 4107 KTRTSTLLP--------SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 4158

Query: 2050 TTLKATGSTHTAPPMTVTTSGTSQTH--------------------------------SS 2077
            + ++A G      P+ +     +Q                                   +
Sbjct: 4159 SNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFN 4218

Query: 2078 FSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSA 2137
            +       ++    S    +S++ P S+P TT +  L+  TT  +TT    S+ +PS S 
Sbjct: 4219 YEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWI--LTELTTTATTTASTGSTATPS-ST 4275

Query: 2138 PSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPL 2197
            P T     P   +SP T+  +  + ++  S+P  +TTL     +S +T  T  SV+    
Sbjct: 4276 PGTAPP--PKVLTSPATTPTATSSKATSSSSPRTATTLP--VLTSTATKSTATSVTP--- 4328

Query: 2198 FPSSPAASTTIRATLPHTISSPF-TLSALLP--------ISTVTVSPTPSSHLASSTIAF 2248
             PSS   +T    TLP   ++P  T+S + P         STV  +   ++   SST   
Sbjct: 4329 IPSSTLGTT---GTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTP 4385

Query: 2249 PSTPRTT--------------ASTHTAPAFSSQSTTSRSTSLTTRVPTSGFV------SL 2288
             STP TT              A+  TA   S+  TT   T LTT   T+         S 
Sbjct: 4386 SSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSS 4445

Query: 2289 TSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTP-TSPG 2347
            T G T I T P T  T   P  + +  +    ++ T H ST A+ P  +    TP +SPG
Sbjct: 4446 TPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPG 4505

Query: 2348 VCS 2350
              +
Sbjct: 4506 TAT 4508



 Score =  259 bits (661), Expect = 3e-68
 Identities = 359/1290 (27%), Positives = 525/1290 (40%), Gaps = 210/1290 (16%)

Query: 1198 PPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPA 1257
            P TTP PP    L TT + P         S+ +G  + T P P++  T    +  P  P 
Sbjct: 3413 PGTTPIPPV---LTTTATTPAATSSTVTPSSALGT-THTPPVPNTTATTHGRSLPPSSPH 3468

Query: 1258 TLTSSKPTASSG-------EPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATA 1310
            T+ ++  +A+SG         P   T+ TP AT+     +T   ++  P+     +R T 
Sbjct: 3469 TVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPS-----SRTTE 3523

Query: 1311 STASPATTSTAQS--TTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPAS 1368
            S  SP TT+   +  T+RTT T  TP+ + TS  LP S       T  T    P+   + 
Sbjct: 3524 SPPSPGTTTPGHTRGTSRTTATA-TPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSE 3582

Query: 1369 TTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATS-- 1426
                + P PG       T +                   +    G P+   G V   S  
Sbjct: 3583 WLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLD 3642

Query: 1427 -------------FHATTTY-------------PTPSHPETTLPTHVPP--------FST 1452
                         F     Y              TP+   T  P+  P          +T
Sbjct: 3643 FGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTT 3702

Query: 1453 SLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQA 1512
            +  T ST +  TP+     T      + T T+  PT   AT S+  A   TP  S T+  
Sbjct: 3703 ATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT 3762

Query: 1513 HSSFSTNKTPTSLHSHTSSTHHPEVTPTST----TTITPNPTS---------TRTRTPVA 1559
             +  S+  TP S  S  ++T  P +  T+T    T+ T  P+S         ++T TP A
Sbjct: 3763 PTVTSSKATPFS--SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 3820

Query: 1560 HTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSH-PQTTLPTHVPP 1618
              ++AT S  P   T H+        S+    TAT+ + T +  TPS  P T   T VP 
Sbjct: 3821 TMSTATPSSTPE--TAHT--------STVLTTTATTTRATGSVATPSSTPGTAHTTKVPT 3870

Query: 1619 FSTS--LVTPST------------HTVITPTHAQMATSASIHSMPTGTIPP-----PTTL 1659
             +T+   VTPS+             T  TPT +    + S  S+P  T  P      TT 
Sbjct: 3871 TTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPS--SVPGTTHTPTVLTTTTTT 3928

Query: 1660 KATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTH---------HAEATSTS 1710
             ATGS  T P+ +  TSGT  +L +  T  T+T   ++ SST             AT+ +
Sbjct: 3929 VATGSMAT-PSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA 3987

Query: 1711 TTNITPNPTS----TGTPPM---TVTTSGTSQSRSSFSTAKTS-TSLHSHTSSTHHPEVT 1762
             T+ T  P+S    T TPP+   T TT G S S SS  T +T+ TS  S T  T H    
Sbjct: 3988 ATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEP 4047

Query: 1763 STSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPT-GTTPISSTGPVTATSFQ 1821
            ST T     +HT   T     H+T A SS  P+  TT SPP+ GTT   + G  TATS  
Sbjct: 4048 STGT-----SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT---TPGHTTATSRT 4099

Query: 1822 TTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASI---HSMP---TG 1875
            T T  P+ +   T LP      S+    P T  V      Q A S  +   + MP    G
Sbjct: 4100 TATATPSKTRTSTLLP------SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGG 4153

Query: 1876 TIPPPTTIKATGSTHTAPPMTPTTSGTSQS--PSSFSTAKTSTSLPYHTSSTHHPEVTP- 1932
                 + I+A G      P+       +Q   P          SL +     +  +V   
Sbjct: 4154 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKF 4213

Query: 1933 ----TSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATS 1988
                     +   +      TP   +T+  SS   T +      T ++  +STG  TAT 
Sbjct: 4214 KMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTG-STATP 4272

Query: 1989 FQTTTTYPTP---SHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGT 2045
              T  T P P   + P TT PT     +TS  +P T T +      + TS +  ST T  
Sbjct: 4273 SSTPGTAPPPKVLTSPATT-PTATSSKATSSSSPRTATTL-----PVLTSTATKSTATSV 4326

Query: 2046 VPPPTTLKATGSTHTAPPMTVTTSGTSQT-HSSFSTATASSSFI---SSSSWLPQNSSSR 2101
             P P++    G+T T P  T T   T  T H S +  T  +S +    +++    +S+S 
Sbjct: 4327 TPIPSS--TLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTST 4384

Query: 2102 PPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT 2161
            P S+P TT +  L+  TT  +TT     + +PS S P T  +++ +  ++  T++ S G+
Sbjct: 4385 PSSTPGTTWI--LTELTTAATTTAATGPTATPS-STPGT--TWILTELTTTATTTASTGS 4439

Query: 2162 SSSFVSAPVHSTTLSSGSHSSLSTHPT--TASVSASPLFPSSPAASTTIRATLPHTI--- 2216
            +++  S P  +  L+  S ++  T PT  TA+ S++     +P  STT  AT P      
Sbjct: 4440 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTT--ATTPTVTSSK 4497

Query: 2217 ----SSPFTLSALLPISTVTVSPT-------PSSHLASSTIAFPSTPRTTASTHTAPAFS 2265
                SSP T +AL  + +   +PT       PSS L ++      T   TA+  TA   S
Sbjct: 4498 ATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSS 4557

Query: 2266 SQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTA 2325
            +  T   ST LT         + T+G TG   +P +   T H       TT+  T++ T 
Sbjct: 4558 TPETVHTSTVLTA-------TATTTGATGSVATPSSTPGTAH-------TTKVPTTTTTG 4603

Query: 2326 HGSTPASAP---------VSSLGTPTPTSP 2346
              +TP+S+P         +S+  TPT T+P
Sbjct: 4604 FTATPSSSPGTALTPPVWISTTTTPTTTTP 4633



 Score =  252 bits (644), Expect = 3e-66
 Identities = 351/1246 (28%), Positives = 506/1246 (40%), Gaps = 171/1246 (13%)

Query: 1199 PTTPQPPTTPQLP--TTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256
            PTTP   T P +P   T + PT+   + GT+ ++G    + P   +  T A+    P   
Sbjct: 1677 PTTPAGSTEPTVPGVATSTLPTRS-ALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGT 1735

Query: 1257 ATLTSSKPTASSGEPPRPTTAVTPQATSGL---------PPTATLRSTATKPTVTQATTR 1307
            A+  S +P          TT++ P  TS L         P T T  S  T  T +Q TTR
Sbjct: 1736 ASTASKEPL---------TTSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTR 1786

Query: 1308 ATAS-------TASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTN---QELPGTTAT 1357
                            T+  A     T   +   A  G     PKS     +  P  +  
Sbjct: 1787 CQPKCEWTEWFDVDFPTSGVAGGDMETFENI--RAAGGKMCWAPKSIECRAENYPEVSID 1844

Query: 1358 QTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRT--TTEYT-TPQTPHTTHSPPTAGS 1414
            Q  G   T +  TG T     Q  R         R     +Y+  P TP  T S  T  S
Sbjct: 1845 Q-VGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTP-ATSSTATPSS 1902

Query: 1415 PVPSTGPVTATSFHATTTYPTPS--HPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT 1472
               +T  +T  +  ATTT  T S   P +TL T  PP         T T  TPT   + +
Sbjct: 1903 TPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPP------KVLTTTATTPT---VTS 1953

Query: 1473 SASNHSAPTGTIPPPTTLKATGSTHTAPPITP-TTSGTSQAHSSFSTNKTPTSLHSHTSS 1531
            S +  S+  GT      L++T +T TA  +TP  +S      +  S   TPT+  S  + 
Sbjct: 1954 SKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATP 2013

Query: 1532 THHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSST--- 1588
            +  PE   TST       T+T T T    + +  SS P    TT  P T ++ F++T   
Sbjct: 2014 SSTPETAHTSTVL-----TATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 2068

Query: 1589 GPMTATS---FKTTTTYPTPSHPQTTLPTHVP--PFSTSLVTPSTHTVITPTHAQMATSA 1643
             P TA +   + +TTT PT +   T  P+ +P    + +++T +T TV T + A  ++S 
Sbjct: 2069 SPGTALTPPVWISTTTTPT-TRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSST 2127

Query: 1644 SIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHH 1703
                 P       TT+ ATGST    T   +T GT+     L T  T+ +  S+T +   
Sbjct: 2128 QTSGTPPSLTTTATTITATGST----TNPSSTPGTTPIPPVLTTTATTPAATSNTVT--- 2180

Query: 1704 AEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS-TSLHSHTSSTHHPEVT 1762
              +++  TT+  P P +        TT G S   SS  T +T+ TS  S    T H  +T
Sbjct: 2181 -PSSALGTTHTPPVPNT------MATTHGRSLPPSSPHTVRTAWTSATSGILGTTH--IT 2231

Query: 1763 STSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPT-GTTPISSTGPVTATSFQ 1821
              ST +   +HT   T     H+T A SS  P+  TT SPP+ GTT   + G  TATS  
Sbjct: 2232 EPSTVT---SHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTT---TPGHTTATSRT 2285

Query: 1822 TTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASI---HSMP---TG 1875
            T T  P+ +   T LP      S+    P T  V +    Q A S  +   + MP    G
Sbjct: 2286 TATATPSKTRTSTLLP------SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGG 2339

Query: 1876 TIPPPTTIKATGSTHTAPPMTPTTSGTSQS--PSSFSTAKTSTSLPY------------- 1920
                 + I+A G      P+       +Q   P          SL +             
Sbjct: 2340 DFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKF 2399

Query: 1921 ----------------------HTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSAS 1958
                                   TSST  P  TP  TT I  + T+T T T    +T+  
Sbjct: 2400 KMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTP-GTTWILTELTTTATTTESTGSTATP 2458

Query: 1959 SSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQT-TLPTHVPPFSTSLV 2017
            SS   T +    P T ++    TG  TAT+  T  T  TP    T T PT     +T   
Sbjct: 2459 SSTPGTTWILTEPSTTATVTVPTG-STATASSTQATAGTPHVSTTATTPTVTSSKATPFS 2517

Query: 2018 TPSTHTVI----ITTHTQMATS-ASIHSTPTGT----VPPPTTLKATGSTHTAPPMTVTT 2068
            +P T T +     T  T  ATS  +I S+  GT    +   TT  AT ST T P  T  T
Sbjct: 2518 SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT-PSSTPET 2576

Query: 2069 SGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQ-- 2126
              TS   ++ +T T ++  +++ S  P  + +    +  TT      S++   + T    
Sbjct: 2577 VHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVW 2636

Query: 2127 LSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTH 2186
            +S++ +P+    +   S +P +  +P   + +  T ++   A   S+T +SG+  SL+T 
Sbjct: 2637 ISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTT 2696

Query: 2187 PTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTI 2246
             TT + + S   PSS   +T I   L  T ++P   S     STV    TPSS  A  T 
Sbjct: 2697 ATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATS-----STV----TPSS--ALGTT 2745

Query: 2247 AFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSP-VTNLTT 2305
              P  P TTA+TH      S   T R+   +    T G   +T   TG   +P  T  TT
Sbjct: 2746 HTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTT 2805

Query: 2306 RHPGPTLS---PTTRFLTS----SLTAHGSTPASAPVSSLGTPTPT 2344
            +H  P LS   P++R   S      T  G T A++  ++  TP+ T
Sbjct: 2806 QHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKT 2851



 Score =  252 bits (644), Expect = 3e-66
 Identities = 313/1148 (27%), Positives = 454/1148 (39%), Gaps = 161/1148 (14%)

Query: 1192 VCVPCMPPTTPQPPTTPQLPTTG-----------SRPTQVWPMTGTS-TTIGLLSSTGPS 1239
            V  P   P T      P   TTG           +R   VW  T T+ TT G   +    
Sbjct: 3853 VATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSV 3912

Query: 1240 PSSNHTPASPTQTPLLPAT---LTSSKPTASSGEPPRP-TTAVTPQATSGLPPTATLRST 1295
            P + HTP   T T    AT    T S  T +SG PP   TTA T  AT      ++   T
Sbjct: 3913 PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGT 3972

Query: 1296 ATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATS---GTSPTLP-------- 1344
               P V   T    A+T+S  T S+A  TT T     T AT+     SP+ P        
Sbjct: 3973 TPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWT 4032

Query: 1345 KSTNQELPGTTATQ-TTGPRPTPASTTGPT----------------TPQPGQPTRPTATE 1387
             +T+  L  T  T+ +TG   TPA+TTG T                T  P  P   T   
Sbjct: 4033 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 4092

Query: 1388 TTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVT-------ATSFHATTTYPTPSHPE 1440
            TT T  TT   TP    T+   P++ +  P T  VT       A S     +YP P    
Sbjct: 4093 TTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSG 4152

Query: 1441 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPT-----------T 1489
                T+      S +  +   V          + +    P G +                
Sbjct: 4153 GDFDTY------SNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRN 4206

Query: 1490 LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHH--PEVTPTSTTTITP 1547
             +  G               +  H   +   + T++ S T  T     E+T T+TTT + 
Sbjct: 4207 REQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTAST 4266

Query: 1548 NPTSTRTRTPVAHTNSATSSRPPP-----PFTTHSPPTGSSPFSSTGPMTATSFKTTTTY 1602
              T+T + TP         + PPP     P TT +  T S   SS+ P TAT+    T+ 
Sbjct: 4267 GSTATPSSTP--------GTAPPPKVLTSPATTPT-ATSSKATSSSSPRTATTLPVLTST 4317

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTI--PPPTTLK 1660
             T S   +  P       T+   P   T    T + +  S++  +  T T+     TT +
Sbjct: 4318 ATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTR 4377

Query: 1661 ATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS 1720
            AT ST T      +T GT+  L+ L TA T+T+    T++      T+   T +T   T+
Sbjct: 4378 ATSSTSTPS----STPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATT 4433

Query: 1721 TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRT 1780
            T +   T T S T  +    +   T+ ++   T ST     +ST  T+ TP H ST   T
Sbjct: 4434 TASTGSTATPSSTPGTTWILTEPSTTATVTVPTGST--ATASSTQATAGTP-HVSTTATT 4490

Query: 1781 PVAHTTSATSS-------RLPTPFTTHSPPTGTT----PISSTGPVTATSFQTTT----- 1824
            P   ++ AT S        LP   +T + PT T+    P SS G       QTTT     
Sbjct: 4491 PTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM 4550

Query: 1825 TYPTPSHPHTTLPTHVPSFST--------SLVTPST-----HTVIIPTHTQMATSASIHS 1871
            +  TPS    T+ T     +T        S+ TPS+     HT  +PT T    +A+  S
Sbjct: 4551 STATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 4610

Query: 1872 MPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSF----STAK--TSTSLPYHTSST 1925
             P   + PP  I  T +  T    TPTTSG++ +PSS      TA+  T+T+    T S 
Sbjct: 4611 SPGTALTPPVWISTTTTPTTT---TPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSM 4667

Query: 1926 HHPEVTPTSTTNITPKHTSTGTR-TPVAHTTSASSSRLPTPFT-------THSPPTGSSP 1977
              P  + T T+   P  T+T T  T    TT+ SS+   TP T       T    T S  
Sbjct: 4668 ATPS-SSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKA 4726

Query: 1978 FSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSAS 2037
             SS+ P TAT+    T+  T S   +  P       T+   P+  T  ++T + + TS++
Sbjct: 4727 TSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSST 4786

Query: 2038 IHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQN 2097
              +T T TV   T      +  TA P   +T GT++  +  +T   +++   S++ L   
Sbjct: 4787 PETTHTSTVLTTTATMTRATNSTATPS--STLGTTRILTELTTTATTTAATGSTATL--- 4841

Query: 2098 SSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPS---------PSAPSTVSSYVPSS 2148
             SS P ++ I T+   +++   P  +T   SS+   +          + P+  +S VPSS
Sbjct: 4842 -SSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSS 4900

Query: 2149 HSSPQTSSPSVGTSS------SFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSP 2202
             +   T +P+V  SS      S VS+ V +T   +G  SS  + P           P   
Sbjct: 4901 STVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEV 4960

Query: 2203 AASTTIRA 2210
              + T RA
Sbjct: 4961 IYNKTDRA 4968



 Score =  247 bits (630), Expect = 1e-64
 Identities = 353/1265 (27%), Positives = 515/1265 (40%), Gaps = 221/1265 (17%)

Query: 1200 TTPQPPTTPQLPTTGSR---PTQVWPM--TGTSTTIGLLSSTG---PSPSSNHTPASPT- 1250
            TT  PP    + TT  R   P+    +    TS T G+L +T    PS  ++HT A+ T 
Sbjct: 2187 TTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTG 2246

Query: 1251 ----QTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATT 1306
                 TP L +   SS+ T S   PP P T  TP  T     TAT R+TAT    T + T
Sbjct: 2247 TTQHSTPALSSPHPSSRTTES---PPSPGTT-TPGHT-----TATSRTTAT---ATPSKT 2294

Query: 1307 RATASTASPATTSTAQSTTRTTM--------------TLPTPATSGTSPTLPKSTNQELP 1352
            R   ST  P++ ++A  TT  TM              + P P  SG       S  +   
Sbjct: 2295 RT--STLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDT-YSNIRAAG 2351

Query: 1353 GTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQT---------- 1402
            G    Q  G      +  G    + GQ    +       R   +    +           
Sbjct: 2352 GAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 2411

Query: 1403 ---PHTTHSPPTAGSPVPSTGP----------VTATSFHATTTYPTPSHPETTLPTHVPP 1449
                H   +P T+ + +PS+ P           TAT+  +T +  TPS    T      P
Sbjct: 2412 CNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEP 2471

Query: 1450 FSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKAT--GSTHTAPPITPTTS 1507
             +T+ VT  T +  T +  Q AT+ + H + T T P  T+ KAT   S  TA  + P   
Sbjct: 2472 STTATVTVPTGSTATASSTQ-ATAGTPHVSTTATTPTVTSSKATPFSSPGTATAL-PALR 2529

Query: 1508 GTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST-TTITPNPTSTRTRTPVAHTNSATS 1566
             T+   ++ S    P+S    T +      TPT+T +T TP+ T     T    T +AT 
Sbjct: 2530 STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTAT- 2588

Query: 1567 SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTT---YPTPSHPQTTLPTHVPPFSTSL 1623
                   TT +  + ++P S+ G    T   TTTT     TPS    T  T +P + ++ 
Sbjct: 2589 -------TTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTART-LPVWISTT 2640

Query: 1624 VTPSTH-TVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQAL 1682
             TP+T  + +TP+     T       PT  +   TT  ATGS  T P+ +  TSGT  +L
Sbjct: 2641 TTPTTRGSTVTPSSIPGTTHT-----PT-VLTTTTTTVATGSMAT-PSSSTQTSGTPPSL 2693

Query: 1683 SSLNTAKTSTSLHSHTSSTH---------HAEATSTSTTNITPNPTS----TGTPPM--- 1726
            ++  T  T+T   ++ SST             AT+ + T+ T  P+S    T TPP+   
Sbjct: 2694 TTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNT 2753

Query: 1727 TVTTSGTSQSRSSFSTAKTS-TSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHT 1785
            T TT G S S SS  T +T+ TS  S T  T H    ST T     +HT   T     H+
Sbjct: 2754 TATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGT-----SHTPAATTGTTQHS 2808

Query: 1786 TSATSSRLPTPFTTHSPPT-GTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFS 1844
            T A SS  P+  TT SPP+ GTT   + G   ATS  T T  P+ +   T LP      S
Sbjct: 2809 TPALSSPHPSSRTTESPPSPGTT---TPGHTRATSRTTATATPSKTRTSTLLP------S 2859

Query: 1845 TSLVTPSTHTVIIPTHTQMATSASI---HSMP---TGTIPPPTTIKATGSTHTAPPMTPT 1898
            +    P T  V +    Q A S  +   + MP    G     + I+A G      P+   
Sbjct: 2860 SPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLE 2919

Query: 1899 TSGTSQS--PSSFSTAKTSTSLPYHTSSTHHPEV-----------------------TPT 1933
                +Q   P          SL +     +  +V                       TP 
Sbjct: 2920 CRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPA 2979

Query: 1934 STTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTT 1993
            +++  TP  T   T      TT+A          T +  TGS+   S+ P TA   +  T
Sbjct: 2980 TSSTATPSSTPGTTWILTEQTTAA----------TTTATTGSTAIPSSTPGTAPPPKVLT 3029

Query: 1994 TYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLK 2053
            +         T PT     +TS  +P T T +      + TS +  ST T   P P+   
Sbjct: 3030 S-------TATTPTATSSKATSSSSPRTATTL-----PVLTSTATKSTATSFTPIPSF-- 3075

Query: 2054 ATGSTHTAPPMTVTTSGTSQT-HSSFSTATASSSFI---SSSSWLPQNSSSRPPSSPITT 2109
              G+T T P  T T   T  T H S +  T  +S +    +++    +S S P S+P TT
Sbjct: 3076 TLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3135

Query: 2110 QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAP 2169
             +  L+  TT  +TT     + +PS +  +T     PS+     T++ +V T S   +A 
Sbjct: 3136 WI--LTELTTAATTTAATGPTATPSSTPGTTWILTEPST-----TATVTVPTGS---TAT 3185

Query: 2170 VHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPIS 2229
              ST  ++G+   L++  TT +V +S   PSS   + T    L  T ++P         +
Sbjct: 3186 ASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTP---------T 3236

Query: 2230 TVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLT 2289
              +V+  PSS L ++      T   TA+  TA   S+  T   ST LTT        + T
Sbjct: 3237 ATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT-------TTTT 3289

Query: 2290 SGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTP-------T 2342
            +  TG   +P +   T H       TT+  T++ T   +TP+S+P ++L  P       T
Sbjct: 3290 TRATGSVATPSSTPGTAH-------TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTT 3342

Query: 2343 PTSPG 2347
            PT+ G
Sbjct: 3343 PTTRG 3347



 Score =  229 bits (584), Expect = 2e-59
 Identities = 301/1124 (26%), Positives = 436/1124 (38%), Gaps = 152/1124 (13%)

Query: 1293 RSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKS-TNQEL 1351
            R  AT P  T     AT +T   A  ST Q T+   +T   PA++   PTL +  T+   
Sbjct: 1607 RGRATTPPPTTELETATTTTTQ-ALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRY 1665

Query: 1352 PGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPT 1411
              T  T TTG   TPA +T PT P     T PT +    T  +     P  P T      
Sbjct: 1666 TSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTM 1725

Query: 1412 AGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMA 1471
            A S    TG  +  S    TT   P     TL + +        TP T T ++P      
Sbjct: 1726 ATSRARPTGTASTASKEPLTTSLAP-----TLTSELSTSQAETSTPRTETTMSPLTNTTT 1780

Query: 1472 TSASNHSAPT------GTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTN------ 1519
            +  +    P         +  PT+  A G   T   I         A  S          
Sbjct: 1781 SQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSIECRAENYPE 1840

Query: 1520 --------------KTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSAT 1565
                          +T  +  +   +         +   +  +  S    TP   + +  
Sbjct: 1841 VSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATP 1900

Query: 1566 SSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVT 1625
            SS P   +    P T ++  +STG  TAT   T  T P P    TT  T  P  ++S  T
Sbjct: 1901 SSTPGTTWILTKPTTTATTTASTG-STATPTSTLRTAPPPKVLTTTATT--PTVTSSKAT 1957

Query: 1626 PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSL 1685
            PS+      T   +    S  + PT T   P    + G+T T  + T T + T    +  
Sbjct: 1958 PSSS---PGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPS 2014

Query: 1686 NTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKT 1745
            +T +T     +HTS+   A AT+T  T       S  TP  T  T+ T++  ++ +T  T
Sbjct: 2015 STPET-----AHTSTVLTATATTTGATG------SVATPSSTPGTAHTTKVPTTTTTGFT 2063

Query: 1746 STSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTG 1805
            +T   S  ++   P   ST+TT  T   T T +  P    T+ T++ L T  TT +  + 
Sbjct: 2064 ATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIP---GTTHTATVLTTTTTTVATGSM 2120

Query: 1806 TTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMAT 1865
             TP SST        QT+ T P+ +   TT+ T   S +    TP T T I P  T  AT
Sbjct: 2121 ATPSSST--------QTSGTPPSLTTTATTI-TATGSTTNPSSTPGT-TPIPPVLTTTAT 2170

Query: 1866 SASIHSMPTGTIPPPTTIKATGSTHTAP-PMT-PTTSGTSQSPSSFSTAKTS-TSLPYHT 1922
            +      P  T    T   A G+THT P P T  TT G S  PSS  T +T+ TS     
Sbjct: 2171 T------PAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGI 2224

Query: 1923 SSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST- 1981
              T H  +T  ST      HT   T     H+T A SS  P+  TT SPP   SP ++T 
Sbjct: 2225 LGTTH--ITEPSTVT---SHTLAATTGTTQHSTPALSSPHPSSRTTESPP---SPGTTTP 2276

Query: 1982 GPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASI-HS 2040
            G  TATS  T T  P+ +   T LP      S+    P T  V +    Q A S  + +S
Sbjct: 2277 GHTTATSRTTATATPSKTRTSTLLP------SSPTSAPITTVVTMGCEPQCAWSEWLDYS 2330

Query: 2041 TPT-----GTVPPPTTLKATGSTHTAPPMTVTTSGTSQTH-------------------- 2075
             P      G     + ++A G      P+ +     +Q                      
Sbjct: 2331 YPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVC 2390

Query: 2076 ------------SSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVST 2123
                         ++       ++    S    +S++ P S+P TT +  L+  TT  +T
Sbjct: 2391 RNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWI--LTELTTTATT 2448

Query: 2124 TNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSL 2183
            T    S+ +PS +  +T     PS+ ++    + S  T+SS         T  +   S+ 
Sbjct: 2449 TESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASS------TQATAGTPHVSTT 2502

Query: 2184 STHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
            +T PT  S  A+P   SSP  +T + A L  T ++P         +  + +  PSS L +
Sbjct: 2503 ATTPTVTSSKATPF--SSPGTATALPA-LRSTATTP---------TATSFTAIPSSSLGT 2550

Query: 2244 STIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNL 2303
            +      T   TA+  TA   S+  T   ST LTT        + T+G TG   +P +  
Sbjct: 2551 TWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTT-------TATTTGATGSVATPSSTP 2603

Query: 2304 TTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPG 2347
             T H    L+ TT   T++ ++   T  + PV    T TPT+ G
Sbjct: 2604 GTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRG 2647



 Score =  222 bits (566), Expect = 3e-57
 Identities = 327/1263 (25%), Positives = 476/1263 (37%), Gaps = 243/1263 (19%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPL 1254
            P    +T  P +TP+   T +       +T T+TT G   S   +PSS    A  T+ P 
Sbjct: 2004 PTATMSTATPSSTPETAHTST------VLTATATTTGATGSVA-TPSSTPGTAHTTKVPT 2056

Query: 1255 LPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRA----TA 1310
               T  ++ P++S G      TA+TP        T T R +   P+    TT      T 
Sbjct: 2057 TTTTGFTATPSSSPG------TALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT 2110

Query: 1311 STASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTT 1370
            +T + AT S A  ++ T        TSGT P+L  +        T    TG    P+ST 
Sbjct: 2111 TTTTVATGSMATPSSST-------QTSGTPPSLTTT-------ATTITATGSTTNPSSTP 2156

Query: 1371 GPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHAT 1430
            G TTP P  P   T T TT   T+   T      TTH+PP                    
Sbjct: 2157 G-TTPIP--PVL-TTTATTPAATSNTVTPSSALGTTHTPPV------------------- 2193

Query: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITP-THAQMATSASNHSAPTGTIPPPTT 1489
                    P T   TH      SL   S HTV T  T A      + H     T+   T 
Sbjct: 2194 --------PNTMATTH----GRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTL 2241

Query: 1490 LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNP 1549
               TG+T  + P        S  H S  T ++P S      +T     T TS TT T  P
Sbjct: 2242 AATTGTTQHSTP------ALSSPHPSSRTTESPPS----PGTTTPGHTTATSRTTATATP 2291

Query: 1550 TSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQ 1609
            + TRT T +             P +  S P  +       P  A S     +YP P    
Sbjct: 2292 SKTRTSTLL-------------PSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPG--- 2335

Query: 1610 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTG-----TIPPPTTLKATGS 1664
                            PS     T ++ + A   ++   P G        P   L+  G 
Sbjct: 2336 ----------------PSGGDFDTYSNIR-AAGGAVCEQPLGLECRAQAQPGVPLRELGQ 2378

Query: 1665 THTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTP 1724
                   +L      +    +   K   +        ++    ST  T+ T  P+S  TP
Sbjct: 2379 ---VVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSS--TP 2433

Query: 1725 PMT-VTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVA 1783
              T + T  T+ + ++ ST  T+T   +  ++    E ++T+T ++    T+T + T   
Sbjct: 2434 GTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQAT 2493

Query: 1784 HTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTA-TSFQTTTTYPTPSH----PHTTL-- 1836
              T   S+   TP  T S     TP SS G  TA  + ++T T PT +     P ++L  
Sbjct: 2494 AGTPHVSTTATTPTVTSSK---ATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGT 2550

Query: 1837 ------PTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTH 1890
                   T  P+ + S  TPS+    + T T + T+A+  +  TG++  P++    G+ H
Sbjct: 2551 TWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATT-TGATGSVATPSS--TPGTAH 2607

Query: 1891 TAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHP-----EVTPTST--TNITPKHT 1943
            T   +T TT+G + +PS  S+  T+ +LP   S+T  P      VTP+S   T  TP   
Sbjct: 2608 TTKVLTTTTTGFTATPS--SSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVL 2665

Query: 1944 STGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQT 2003
            +T T T    + +  SS   T  T  S  T ++  ++TG   +T+  ++T   TP  P  
Sbjct: 2666 TTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATG---STTNPSSTPGTTPIPPVL 2722

Query: 2004 TLPTHVPPFSTSLVTPS-----THT-----VIITTHTQMATSASIHSTPTGTVPPPTTLK 2053
            T     P  ++S VTPS     THT        TTH +  + +S H+  T       T  
Sbjct: 2723 TTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWT--SATSG 2780

Query: 2054 ATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPH 2113
              G+TH   P T    GTS T ++ +T T   S  + SS  P + ++  P SP TT   H
Sbjct: 2781 TLGTTHITEPST----GTSHTPAA-TTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 2835

Query: 2114 --LSSATTPVSTTNQLSSSF---SPSPSAPSTV------------SSYVPSSHSSPQTSS 2156
               +S TT  +T ++  +S    S   SAP T             S ++  S+  P  S 
Sbjct: 2836 TRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSG 2895

Query: 2157 PSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIR------- 2209
                T S+  +A         G        P         +   S       R       
Sbjct: 2896 GDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGK 2955

Query: 2210 -------------ATLPHTISSPFTLSALLPIST--------------VTVSPTPSSHLA 2242
                             H  S+P T S   P ST               T + T S+ + 
Sbjct: 2956 FKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIP 3015

Query: 2243 SSTIAFPSTPRTTASTHTAPAFSSQSTTSRS-----------TSLTTRVPTSGFV---SL 2288
            SST      P+   ST T P  +S   TS S           TS  T+   + F    S 
Sbjct: 3016 SSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSF 3075

Query: 2289 TSGVTGI----PTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPT 2344
            T G TG      T+P+  ++T HP  T  P T   ++ LT   +T  +   SS+ TP+ T
Sbjct: 3076 TLGTTGTLPEQTTTPMATMSTIHPSST--PETTHTSTVLTTKATT--TRATSSMSTPSST 3131

Query: 2345 SPG 2347
             PG
Sbjct: 3132 -PG 3133



 Score =  134 bits (337), Expect = 1e-30
 Identities = 197/756 (26%), Positives = 300/756 (39%), Gaps = 98/756 (12%)

Query: 1646 HSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAE 1705
            H     T PPPTT   T +T T   +  T   TS    +     ++T++ + +       
Sbjct: 1605 HCRGRATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPR 1664

Query: 1706 ATSTSTTNITPNPTS-TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTST 1764
             TST  T  T  PT+  G+   TV    TS       T  T ++L   T S        T
Sbjct: 1665 YTSTLGTATTGGPTTPAGSTEPTVPGVATS-------TLPTRSALPGTTGSL------GT 1711

Query: 1765 STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTT 1824
               S  P    T   T  A  T   S+    P TT   PT T+ +S++   T+T    TT
Sbjct: 1712 WRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETT 1771

Query: 1825 TYPTPSHPHTTLPTHVPS-------FSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI 1877
              P  +   +   T           F     T       + T   +  +         +I
Sbjct: 1772 MSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPKSI 1831

Query: 1878 P------PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFS-----TAKTSTSLPY-HTSST 1925
                   P  +I   G   T    T  T         F+       +      Y H  ST
Sbjct: 1832 ECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHCPST 1891

Query: 1926 HHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP 1983
              P  + T+T + TP  T   T+     TT+AS+    TP +T   +PP      ++T P
Sbjct: 1892 --PATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTP 1949

Query: 1984 MTATSFQTTTTYPTPSHPQTTLP----THVPPFSTSLVTPSTHTVIITTHTQMATSASIH 2039
               +S  T ++ P  +   T LP    T   P +TS VTP   + + TT T+++ +    
Sbjct: 1950 TVTSSKATPSSSPGTA---TALPALRSTATTPTATS-VTPIPSSSLGTTWTRLSQT---- 2001

Query: 2040 STPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHS----SFSTATASSSFISSSSWLP 2095
            +TPT T+   T      + HT+  +T T + T  T S    S +  TA ++ + +++   
Sbjct: 2002 TTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTT--T 2059

Query: 2096 QNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTS 2155
               ++ P SSP T   P +  +TT   TT    S+ +PS S P T  +    + ++   +
Sbjct: 2060 TGFTATPSSSPGTALTPPVWISTTTTPTTR--GSTVTPS-SIPGTTHTATVLTTTTTTVA 2116

Query: 2156 SPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHT 2215
            + S+ T SS        +T +SG+  SL+T  TT + + S   PSS   +T I   L  T
Sbjct: 2117 TGSMATPSS--------STQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTT 2168

Query: 2216 ISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH--TAPAFSSQSTTSRS 2273
             ++P   S     +TVT    PSS L   T   P  P T A+TH  + P  S  +  +  
Sbjct: 2169 ATTPAATS-----NTVT----PSSALG--TTHTPPVPNTMATTHGRSLPPSSPHTVRTAW 2217

Query: 2274 TSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLS---PTTRFLTS--------- 2321
            TS T+ +  +  ++  S VT   T   T  TT+H  P LS   P++R   S         
Sbjct: 2218 TSATSGILGTTHITEPSTVTS-HTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP 2276

Query: 2322 ------SLTAHGSTPASAPVSSLGTPTPTSPGVCSV 2351
                  S T   +TP+    S+L   +PTS  + +V
Sbjct: 2277 GHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 2312



 Score =  103 bits (256), Expect = 3e-21
 Identities = 111/353 (31%), Positives = 156/353 (44%), Gaps = 49/353 (13%)

Query: 1198 PPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPA 1257
            P  T    T    P T    T +   T T+   G +++   +P + HT   PT T     
Sbjct: 3261 PTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTT----T 3316

Query: 1258 TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPAT 1317
            T  ++ P++S      P TA+TP        T T R +    TVT ++   T  TA+  T
Sbjct: 3317 TGFTATPSSS------PGTALTPPVWISTTTTPTTRGS----TVTPSSIPGTTHTATVLT 3366

Query: 1318 TSTAQSTTRTTMTLPTPA----TSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPT 1373
            T+T   TT  T ++ TP+    TSGT P+L  +        T    TG    P+ST G T
Sbjct: 3367 TTT---TTVATGSMATPSSSTQTSGTPPSLTTT-------ATTITATGSTTNPSSTPG-T 3415

Query: 1374 TPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTY 1433
            TP P  P   T T TT   T++  T      TTH+P     PVP+T   TAT+ H  +  
Sbjct: 3416 TPIP--PVL-TTTATTPAATSSTVTPSSALGTTHTP-----PVPNT---TATT-HGRSLP 3463

Query: 1434 PTPSHPETTLPTHVPP---FSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTL 1490
            P+  H   T  T        +T +  PST T  TP      TS + HS P  + P P++ 
Sbjct: 3464 PSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPA---ATTSTTQHSTPALSSPHPSS- 3519

Query: 1491 KATGSTHTAPPITP-TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST 1542
            + T S  +    TP  T GTS+  ++ + +KT TS    +S T  P  T  +T
Sbjct: 3520 RTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 3572



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 126/533 (23%), Positives = 187/533 (35%), Gaps = 81/533 (15%)

Query: 391  RPCPGH------CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGV 444
            +PC  H      CS+ GGS  +TFD   Y F G CTY+L++       G L    D    
Sbjct: 5066 QPCDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIH-ARFGNLSLYLDNHYC 5124

Query: 445  SHSETSLVA------------------VVYLSRQDKIVISQDEVVTNNGEAK-WLPYKTR 485
            + S T+  A                  V  +  +++ +I  D++  ++G +K  +     
Sbjct: 5125 TASATAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVL 5184

Query: 486  NITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFT 545
              T  R     L ++ +F  +       +FQA +     F   T G CG    +  DD  
Sbjct: 5185 GTTTMRVDIPALGVSVTFNGQ-------VFQARLPYS-LFHNNTEGQCGTCTNNQRDDCL 5236

Query: 546  TSMGIAEGTASLFVDSW-----RAGNCPAALERETDPCSMSQLNKVCAETHCSML----L 596
               G    +      +W     R   C A           + ++     T C       L
Sbjct: 5237 QRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDL 5296

Query: 597  RTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSS 656
                VF  CH  V P PF+  C+   C      P  C +L  Y   C  RGV    WR +
Sbjct: 5297 MLSQVFAECHNLVPPGPFFNACISDHCRGRLEVP--CQSLEAYAELCRARGVCS-DWRGA 5353

Query: 657  VDN-CTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYL--NQKG 713
                C + C     +         TC S  +++ +    A   +GC CP+   L     G
Sbjct: 5354 TGGLCDLTCPPTKVYKPCGPIQPATCNS-RNQSPQLEGMA---EGCFCPEDQILFNAHMG 5409

Query: 714  ECVRKAQCPCI-LEGYKFILAEQSTVINGITCHCINGRLSCPQRP-----QMFLASCQAP 767
             CV+   CPC+  +G+     E+  V N  +C C  G +S   +P     Q     C  P
Sbjct: 5410 ICVQ--ACPCVGPDGFPKFPGER-WVSNCQSCVCDEGSVSVQCKPLPCDAQGQPPPCNRP 5466

Query: 768  KTFKSCSQSSENKFGAACAPTCQMLATGVACVPT--KCEPGCVCAEGLYENADGQCVPPE 825
                     +EN     C P    +     C  +   C PG    E +    +G C P  
Sbjct: 5467 GFVTVTRPRAEN----PCCPETVCVCNTTTCPQSLPVCPPG---QESICTQEEGDCCPTF 5519

Query: 826  ECP---CEFSGVSYPGGAEL--HTDCRTCSCSRG-----RWACQQGTHCPSTC 868
             C    C ++G  Y  GA       C  C+C  G        CQ+     +TC
Sbjct: 5520 RCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTTC 5572



 Score = 99.0 bits (245), Expect = 5e-20
 Identities = 98/377 (25%), Positives = 152/377 (40%), Gaps = 59/377 (15%)

Query: 858  CQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVIC 917
            C     C   C+++G  H  TFDG  + F GNC Y+L  ++   +       +  +N  C
Sbjct: 5068 CDFHYECECICSMWGGSHYSTFDGTSYTFRGNCTYVLMREI---HARFGNLSLYLDNHYC 5124

Query: 918  GNSGVT----CSRAIKIFLGGLSVVLADRNYTVTGEEPHV----QLGVTPGALSLVVDIS 969
              S       C RA+ I    + +VL      V G+E  +    Q+ V+ G     V +S
Sbjct: 5125 TASATAAAARCPRALSIHYKSMDIVLTVT--MVHGKEEGLILFDQIPVSSGFSKNGVLVS 5182

Query: 970  IPGRYNLTL---IWNRHMTILIRIARAS------QDPLCGLCGNFNGNMKDDFETRSRYV 1020
            + G   + +        +T   ++ +A        +   G CG    N +DD   R    
Sbjct: 5183 VLGTTTMRVDIPALGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTT 5242

Query: 1021 ASSELELVNSWKESPLCGDVSFV---TDPCSLNAFRRSWA--------ERKCSVINSQTF 1069
            A+S  ++  +W       D  +    T P +  A   S          +  C ++ SQ F
Sbjct: 5243 AASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVF 5302

Query: 1070 ATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWR--TPAFC 1127
            A CH+ V   P++ AC+ D C     G  E  C ++ AYA+ C  +GVC DWR  T   C
Sbjct: 5303 AECHNLVPPGPFFNACISDHC----RGRLEVPCQSLEAYAELCRARGVCSDWRGATGGLC 5358

Query: 1128 PIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNI-EGCYNCSQDE-Y 1185
             + C     +   G                QP  C S+ QS     + EGC+ C +D+  
Sbjct: 5359 DLTCPPTKVYKPCG--------------PIQPATCNSRNQSPQLEGMAEGCF-CPEDQIL 5403

Query: 1186 FDHEEGVCV---PCMPP 1199
            F+   G+CV   PC+ P
Sbjct: 5404 FNAHMGICVQACPCVGP 5420



 Score = 85.5 bits (210), Expect = 6e-16
 Identities = 96/393 (24%), Positives = 145/393 (36%), Gaps = 48/393 (12%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRR-----GPDGSISR--- 96
            CS WG  H+STFD   Y F G C Y+        F   S+ L           + +R   
Sbjct: 5078 CSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAARCPR 5137

Query: 97   -IIVELGASVVTVSEAIISVKDIGVI-------SLPYTSNGLQITPFGQSVRLVAKQLEL 148
             + +   +  + ++  ++  K+ G+I       S  ++ NG+ ++  G +   V     L
Sbjct: 5138 ALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPA-L 5196

Query: 149  ELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGK-----------FLEP 197
             + V +        L    +     G CG       ++ +  +G            +L P
Sbjct: 5197 GVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVP 5256

Query: 198  --HKFAALQKLDDPGEICTFQDIPSTHV-RQAQHARICTQLLTLVAPECS--VSKEPFVL 252
               K         P        + ST          +C  +L+ V  EC   V   PF  
Sbjct: 5257 DSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFN 5316

Query: 253  SCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSP--GLCSVGQCPANQVYQE 310
            +C +D        P    C +L  Y+  C   G     WR    GLC +  CP  +VY+ 
Sbjct: 5317 ACISDHCRGRLEVP----CQSLEAYAELCRARGV-CSDWRGATGGLCDL-TCPPTKVYKP 5370

Query: 311  CGSACVKTCSNPQHSCS-SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAP 368
            CG     TC++   S        GCFCPE  +   L N H  + V  CPCV   G    P
Sbjct: 5371 CGPIQPATCNSRNQSPQLEGMAEGCFCPEDQI---LFNAHMGICVQACPCVGPDGFPKFP 5427

Query: 369  GEVTIAACQTCRCTLGRWVCTERPCPGHCSLEG 401
            GE  ++ CQ+C C  G      +P P  C  +G
Sbjct: 5428 GERWVSNCQSCVCDEGSVSVQCKPLP--CDAQG 5458



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 2349 CSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLEL 2408
            C VR     +  +GC   V +T CEG+C  A+ ++   Q +  +C+CC+    +E+ + L
Sbjct: 5661 CQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPL 5720

Query: 2409 PCPDPSTPGRRLVLTLQVFSHCVCS 2433
             CP+    G  ++ T      C C+
Sbjct: 5721 HCPN----GSAILHTYTHVDECGCT 5741


>gi|169202626 PREDICTED: similar to mucin 5, partial [Homo sapiens]
          Length = 2013

 Score =  955 bits (2468), Expect = 0.0
 Identities = 671/2011 (33%), Positives = 920/2011 (45%), Gaps = 234/2011 (11%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGS---ISRIIVEL 101
            CSTWG+ H+ TFD  V+ F G CNY+F+  C  A+  F++QLRR  + +   +SR+++++
Sbjct: 81   CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140

Query: 102  GASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLM 161
               V+ +++  + V    V+ LP++ +G+ I    QS      +  L L ++W  D  L+
Sbjct: 141  DGVVIQLTKGSVLVNGHPVL-LPFSQSGVLIQ---QSSSYTKVEARLGLVLMWNHDDSLL 196

Query: 162  VLVERKYMGQMCGLCGNFDGK-VTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS 220
            + ++ KY  + CGLCG+F+G  V +E +S   K L P +F  LQK+DDP E C    +P 
Sbjct: 197  LELDTKYANKTCGLCGDFNGMPVVSELLSHNTK-LTPMEFGNLQKMDDPTEQCQ-DPVPE 254

Query: 221  THVRQAQHARICTQLL---TLVAPECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEY 277
                 +    IC +LL           V    ++ +C+ D+         +  C TL+EY
Sbjct: 255  PPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEY 314

Query: 278  SRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CSSSCTFGCF 335
            SRQC+  G   + WR P  C   +CP N  Y EC S C  TCSN +HS  C   C  GCF
Sbjct: 315  SRQCTHAGGLPQDWRGPDFCPQ-KCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCF 373

Query: 336  CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPG 395
            CPEGTVL+D+     CVPV++C CV +GA YAPG      C  C C+ GRW C E PCPG
Sbjct: 374  CPEGTVLDDIGQTG-CVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG 432

Query: 396  HCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVV 455
             CS+ GG+  +TFD + Y  HG C+Y+L + P       ++A   + G++ SET L +V 
Sbjct: 433  TCSVLGGAHFSTFDGKQYTVHGDCSYVLTK-PCDSSAFTVLAELRRCGLTDSETCLKSVT 491

Query: 456  YL--SRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRP 513
                  Q  +VI     V  N     LP    N+T+FR ++  +   TS GL+L +QL P
Sbjct: 492  LSLDGVQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVP 551

Query: 514  IFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA-GNCPAALE 572
              Q ++ + P+ RGQT GLCGNFN    DDF T  G+ E TA+ F ++++    CP    
Sbjct: 552  TMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRN 611

Query: 573  RETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHI 632
               DPCS+S  N+  A+  CS L      F RCHA V P  +Y  C++  CN E +   +
Sbjct: 612  SFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCMFDTCNCERSEDCL 671

Query: 633  CAALGDYVHACSLRGVLLWGWRSSVDNCTIP---CTGNTTFSYNSQACERTCLSLSDRAT 689
            CAAL  YVHAC+ +GV L GWR  V  CT P   C  + T+ Y+   C+ TC SLS+   
Sbjct: 672  CAALSSYVHACAAKGVQLGGWRDGV--CTKPMTTCPKSMTYHYHVSTCQPTCRSLSEGDI 729

Query: 690  ECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCING 749
             C    +PVDGC CP GT+L+  G+CV+ + CPC   G   I   +S   +G  C C +G
Sbjct: 730  TCSVGFIPVDGCICPKGTFLDDTGKCVQASNCPCYHRG-SMIPNGESVHDSGAICTCTHG 788

Query: 750  RLSC--PQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGC 807
            +LSC   Q P      C AP  F  C  ++    GA C  +C  L   + C   +C PGC
Sbjct: 789  KLSCIGGQAPAPV---CAAPMVFFDCRNATPGDTGAGCQKSCHTL--DMTCYSPQCVPGC 843

Query: 808  VCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPST 867
            VC +GL  + +G C+  E+CPC  +  SY  G  +   C TC+C    W C     C +T
Sbjct: 844  VCPDGLVADGEGGCITAEDCPCVHNEASYRAGQTIRVGCNTCTCDSRMWRCTDDP-CLAT 902

Query: 868  CTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDS-QPTFKILTENVICGNSGVTCSR 926
            C +YG+GH +TFDGQ + F+G+CEY L  + CG  DS Q +F+++TENV CG +G TCS+
Sbjct: 903  CAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKDSTQDSFRVVTENVPCGTTGTTCSK 962

Query: 927  AIKIFLGGLSVVLADRNYTVTG--EEPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHM 984
            AIKIFLGG  + L+     V G  E   V   +    + LVVD  I     L L+W++  
Sbjct: 963  AIKIFLGGFELKLSHGKVEVIGTDESQEVPYTIRQMGIYLVVDTDI----GLVLLWDKKT 1018

Query: 985  TILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDVSFVT 1044
            +I I ++   +  +CGLCGNF+    +DF TRSR V    LE  NSWK SP C D     
Sbjct: 1019 SIFINLSPEFKGRVCGLCGNFDDIAVNDFATRSRSVVGDVLEFGNSWKLSPSCPDALAPK 1078

Query: 1045 DPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDA 1104
            DPC+ N FR+SWA+++CS+++  TFA CH+ V    YYEACV DAC CDSGGDCEC C A
Sbjct: 1079 DPCTANPFRKSWAQKQCSILHGPTFAACHAHVEPARYYEACVNDACACDSGGDCECFCTA 1138

Query: 1105 VAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPC--LC 1162
            VAAYAQAC + G+CV WRTP+ CP++C +YN              E  C WHYQPC   C
Sbjct: 1139 VAAYAQACHEVGLCVSWRTPSICPLFCDYYN-------------PEGQCEWHYQPCGVPC 1185

Query: 1163 PSQPQSVPGS------NIEGCY-NCSQD-EYFDHEEGVCVPCMPPTTPQPPTTPQLPTTG 1214
                ++  G        +EGCY  C  +   FD ++  CV     T P PP  P+    G
Sbjct: 1186 LRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFDEDKMQCV----ATCPTPPLPPRCHVHG 1241

Query: 1215 S--RPTQVWP------------------------------------------MTGTSTTI 1230
               RP  V P                                            GT   I
Sbjct: 1242 KSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRFHPGDVIYHTTDGTGGCI 1301

Query: 1231 GLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKP--TASSGEPPR--PTTAVTPQATSGL 1286
                    +      P SPT TP+ P T + S P    SS   P   P++A T   +S  
Sbjct: 1302 SARCGANGTIERRVYPCSPT-TPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAW 1360

Query: 1287 PPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTT-----MTLPTPATSG--- 1338
            P TA        PT + +           +         R T      TL      G   
Sbjct: 1361 PTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRV 1420

Query: 1339 -TSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPT-------------RPT 1384
              SP   +   ++ PG    +  G R   +   G T     Q +              P 
Sbjct: 1421 CESPRSVECRAEDAPG-VPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPL 1479

Query: 1385 ATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHP----- 1439
            A  T+   ++   TTP T   T     +GS  PS+ P T +   A TT P P        
Sbjct: 1480 ACSTS---SSPAQTTPPTTSKTTETRASGSSAPSSTPGTVSLSTARTT-PAPGTATSVKK 1535

Query: 1440 --ETTLPTHVPPFST---SLVTPSTHTVIT-PTHAQMATSASNHSAPT------GTIPPP 1487
               T  P  VP  ST   S  TP T  V + PT  + +TS+      T      G+ P P
Sbjct: 1536 TFSTPSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAP 1595

Query: 1488 ----------TTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEV 1537
                        L+  G T    P       + Q  +    N     L      +H   +
Sbjct: 1596 GINGGDFDTFQNLRDEGYTFCESP------RSVQCRAESFPNTPLADLGQDVICSHTEGL 1649

Query: 1538 TPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFK 1597
               +   + P   +   R     T +       PP T  +      P   TG  T T+F 
Sbjct: 1650 ICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHP---TGAQTQTTF- 1705

Query: 1598 TTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGT----I 1653
             TT  P+ S  Q T  +   P +TS VT  THT  TP       + + H   T T    +
Sbjct: 1706 -TTHMPSASTEQPTATSRGGPTATS-VTQGTHT--TP------VTRNCHPRCTWTKWFDV 1755

Query: 1654 PPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTN 1713
              P+     G   T   +  +     +    +   +     H   S  H  +    S   
Sbjct: 1756 DFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREE 1815

Query: 1714 --ITPNPTSTG----------------TP---PMT---VTTSGTSQSRSSFSTAKTSTSL 1749
              +  N    G                TP   P+T   VT   T   R+   T  TS+  
Sbjct: 1816 GLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQ 1875

Query: 1750 HSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPI 1809
             S T++      TST  TS T  HT++ T  P A TTSA     PT  TT + P  TT  
Sbjct: 1876 KSRTTTLVTTSTTSTPQTSTTYAHTTSTTSAPTARTTSA-----PTTRTTSASPASTT-- 1928

Query: 1810 SSTGP-VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSAS 1868
              +GP  T +   TT+T   P+   T+ PT   + +TS  T ST +    + T   TS++
Sbjct: 1929 --SGPGNTPSPVPTTSTISAPTTSITSAPT---TSTTSAPTSSTTSAPTTSTTSAPTSST 1983

Query: 1869 IHSMPTGTIPPPTTIKATGSTHTAPPMTPTT 1899
              S  T T   PTT   T    T P   PTT
Sbjct: 1984 TSSPQTSTTSAPTT-STTSGPGTTPSPVPTT 2013



 Score =  126 bits (317), Expect = 2e-28
 Identities = 111/386 (28%), Positives = 160/386 (41%), Gaps = 37/386 (9%)

Query: 35  SPQTAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSI 94
           S Q  P  G CS  G  HFSTFD   Y   G C+Y+    C  +  T   +LRR      
Sbjct: 424 SCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDS 483

Query: 95  SRIIVELGASVVTVSEAIISVKDIGVISLP--YTS---NGLQITPFGQSVRLVAKQ--LE 147
              +  +  S+  V + ++ +K  G + L   YT    +   +T F  S   +  Q  L 
Sbjct: 484 ETCLKSVTLSLDGV-QTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLG 542

Query: 148 LELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-------KFLEPHKF 200
           L+L +   P   L + +  K  GQ CGLCGNF+    ++F +  G        F    K 
Sbjct: 543 LQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKT 602

Query: 201 AALQKLDDPGEICTFQDIPSTHVRQAQHAR-ICTQLLTLVAP--ECSVSKEP--FVLSCQ 255
            A      P    +F+D  S  V   ++A+  C+QL     P   C  + +P  +  +C 
Sbjct: 603 QAA----CPNIRNSFEDPCSLSVENEKYAQHWCSQLTDADGPFGRCHAAVKPGTYYSNCM 658

Query: 256 ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCS--VGQCPANQVYQECGS 313
            D     +   ++  CA LS Y   C+  G  +  WR  G+C+  +  CP +  Y    S
Sbjct: 659 FDTCNCER--SEDCLCAALSSYVHACAAKGVQLGGWRD-GVCTKPMTTCPKSMTYHYHVS 715

Query: 314 ACVKTC---SNPQHSCSSSC--TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAP 368
            C  TC   S    +CS       GC CP+GT L+D      CV  + CPC   G+M   
Sbjct: 716 TCQPTCRSLSEGDITCSVGFIPVDGCICPKGTFLDDTGK---CVQASNCPCYHRGSMIPN 772

Query: 369 GEVTIAACQTCRCTLGRWVCTERPCP 394
           GE    +   C CT G+  C     P
Sbjct: 773 GESVHDSGAICTCTHGKLSCIGGQAP 798



 Score =  121 bits (303), Expect = 1e-26
 Identities = 108/420 (25%), Positives = 170/420 (40%), Gaps = 54/420 (12%)

Query: 21   NTSYTSPGLQRLKDSPQTAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAA------- 73
            NT      + R  D P  A     C+ +G GH+ TFD   Y F+G C Y           
Sbjct: 883  NTCTCDSRMWRCTDDPCLAT----CAVYGDGHYLTFDGQSYSFNGDCEYTLVQNHCGGKD 938

Query: 74   TCKDAFPTFSVQLRRGPDGSI--SRIIVELGASVVTVSEAIISVKDIGV---ISLPYTSN 128
            + +D+F   +  +  G  G+     I + LG   + +S   + V  IG      +PYT  
Sbjct: 939  STQDSFRVVTENVPCGTTGTTCSKAIKIFLGGFELKLSHGKVEV--IGTDESQEVPYTIR 996

Query: 129  GLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFV 188
             + I         +    ++ L ++W   + + + +  ++ G++CGLCGNFD    N+F 
Sbjct: 997  QMGI--------YLVVDTDIGLVLLWDKKTSIFINLSPEFKGRVCGLCGNFDDIAVNDFA 1048

Query: 189  SEEGKFL-EPHKFAALQKLDD--PGEICTFQDIPSTHVRQAQHARICTQLLTLVAPECSV 245
            +     + +  +F    KL    P  +       +   R++   + C+ L       C  
Sbjct: 1049 TRSRSVVGDVLEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACHA 1108

Query: 246  SKEP--FVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSV---- 299
              EP  +  +C  D  A    G     C  ++ Y++ C  VG  V  WR+P +C +    
Sbjct: 1109 HVEPARYYEACVNDACACDSGGDCECFCTAVAAYAQACHEVGLCV-SWRTPSICPLFCDY 1167

Query: 300  ----GQCPANQVYQECGSACVKTCSNPQHSCSSSC--TFGCF--CPEGTVLNDLSNNHTC 351
                GQC  +  YQ CG  C++TC NP+  C        GC+  CP    + D  +   C
Sbjct: 1168 YNPEGQCEWH--YQPCGVPCLRTCRNPRGDCLRDVWGLEGCYPKCPPEAPIFD-EDKMQC 1224

Query: 352  VPVTQCP-----CVLHGAMYAPGEVTIA--ACQTCRCTLGRWVCTERPCPGHCSLEGGSF 404
            V     P     C +HG  Y PG V  +   CQ+C CT     CT +     C+  G  F
Sbjct: 1225 VATCPTPPLPPRCHVHGKSYRPGAVVPSDKNCQSCLCTERGVECTYKAEACVCTYNGQRF 1284



 Score =  100 bits (248), Expect = 2e-20
 Identities = 194/784 (24%), Positives = 284/784 (36%), Gaps = 125/784 (15%)

Query: 1563 SATSSRPPPPFTTHSPP--TGSSPFSSTGPMTATSFKTTTTYPTPS--HPQTTLPTHVPP 1618
            S T+  PP  F+  +PP    S+   S GP +A +   ++ +PT +   P+T LPT    
Sbjct: 1319 SPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPT---- 1374

Query: 1619 FSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATG------------STH 1666
               S   P            M  S       +G       L+A G               
Sbjct: 1375 --ASASLPPVCGEKCLWSPWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPRSVECRAE 1432

Query: 1667 TAPTMTLTTSGT------SQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS 1720
             AP + L   G          L+  N  + S   +++          + ST++   +P  
Sbjct: 1433 DAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSS---SPAQ 1489

Query: 1721 TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRT 1780
            T TPP   TTS T+++R+S S+A +ST           P   S ST   TP   + GT T
Sbjct: 1490 T-TPP---TTSKTTETRASGSSAPSST-----------PGTVSLSTARTTP---APGTAT 1531

Query: 1781 PVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTAT-SFQTTTTYPTPSHPHTTLPTH 1839
             V  T S  S   P P     P T T+ +S+T P T+  S + T T P+ S     L T 
Sbjct: 1532 SVKKTFSTPS---PPPV----PATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTW 1584

Query: 1840 VPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTT 1899
                  S   P  +     T   +                P +++    +    P+    
Sbjct: 1585 TEWIDGSYPAPGINGGDFDTFQNLRDEGYTFC------ESPRSVQCRAESFPNTPLADLG 1638

Query: 1900 SGTSQSPSSFSTAKTSTSLP---YHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTS 1956
                 S +          LP   Y+         T     +IT    +  T  P  H T 
Sbjct: 1639 QDVICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTG 1698

Query: 1957 ASSSRLPTPFTTHSPPTGSSPFSST--GPMTATSFQTTTTYPTP----SHPQTTLPTHVP 2010
            A +    T FTTH P   +   ++T  G  TATS  T  T+ TP     HP+ T      
Sbjct: 1699 AQTQ---TTFTTHMPSASTEQPTATSRGGPTATSV-TQGTHTTPVTRNCHPRCTWTKW-- 1752

Query: 2011 PFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSG 2070
             F     +P  H     T+  +  S          +   T L+    +H  P +++   G
Sbjct: 1753 -FDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEI---TRLQCRAKSH--PEVSIEHLG 1806

Query: 2071 TSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSS 2130
                 S        +        +  N   R          P  S+  T  ST +    +
Sbjct: 1807 QVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPS--GRA 1864

Query: 2131 FSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTA 2190
             SP+ S  S   S   +  ++  TS+P   T+ +      H+T+ +S   +  ++ PTT 
Sbjct: 1865 ISPTQSTSSWQKSRTTTLVTTSTTSTPQTSTTYA------HTTSTTSAPTARTTSAPTTR 1918

Query: 2191 SVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPS 2250
            + SASP       ASTT         S P            T SP P++    STI+ P+
Sbjct: 1919 TTSASP-------ASTT---------SGPGN----------TPSPVPTT----STISAPT 1948

Query: 2251 TPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGP 2310
            T  T+A T +  +  + STTS  T+ TT  PTS   S TS      TS  T  TT  PG 
Sbjct: 1949 TSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTS---STTSSPQTSTTSAPTTSTTSGPGT 2005

Query: 2311 TLSP 2314
            T SP
Sbjct: 2006 TPSP 2009



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 78/282 (27%), Positives = 120/282 (42%), Gaps = 32/282 (11%)

Query: 863  HCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGV 922
            H    C+ +G  H  TFDG  F F G C Y+  ++ CG        ++        ++  
Sbjct: 76   HNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVF-SEHCGAAYEDFNIQLRRSQ---ESAAP 131

Query: 923  TCSRAIKIFLGGLSVVLADRNYTVTGEE---PHVQLGVTPGALSLVVDISIPGRYNLTLI 979
            T SR + + + G+ + L   +  V G     P  Q GV     S      +  R  L L+
Sbjct: 132  TLSRVL-MKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYT--KVEARLGLVLM 188

Query: 980  WNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL-CG 1038
            WN   ++L+ +     +  CGLCG+FNG               SEL L ++ K +P+  G
Sbjct: 189  WNHDDSLLLELDTKYANKTCGLCGDFNG-----------MPVVSEL-LSHNTKLTPMEFG 236

Query: 1039 DVSFVTDPCSLNAFRRSWAERKCS--------VINSQTFATCHSKVYHLPYYEACVRDAC 1090
            ++  + DP            R CS        +++ Q F+ C + V    Y EAC +D C
Sbjct: 237  NLQKMDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLC 296

Query: 1091 GCDSGGDCECLCDAVAAYAQACLDK-GVCVDWRTPAFCPIYC 1131
             C+      C+C  +A Y++ C    G+  DWR P FCP  C
Sbjct: 297  FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKC 338



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 188/788 (23%), Positives = 276/788 (35%), Gaps = 136/788 (17%)

Query: 1361 GPRPTPASTTGPTTPQPGQ--PTRPTATETTQTRTTTEYTTPQTPHTTHS---PP--TAG 1413
            G R  P      TT   G     R  A  T + R      T   P TT S   PP   + 
Sbjct: 1281 GQRFHPGDVIYHTTDGTGGCISARCGANGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSS 1340

Query: 1414 SPVPSTGPVTATSFHATTTYPTPS--HPETTLPT---HVPPFSTSLVTPSTHTVITP--- 1465
            +  PS GP +A +   ++ +PT +   P T LPT    +PP        S    ++    
Sbjct: 1341 THTPSNGPSSAHTGPPSSAWPTTAGTSPRTRLPTASASLPPVCGEKCLWSPWMDVSRPGR 1400

Query: 1466 --------------THAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQ 1511
                           H      +           P   L+A G      P    T    +
Sbjct: 1401 GTDSGDFDTLENLRAHGYRVCESPRSVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNRE 1460

Query: 1512 AHSSFSTN-----KTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566
              S    N     +  T L   TSS+      P  TT     PT+++T    A  +SA S
Sbjct: 1461 QASGLCYNYQIRVQCCTPLACSTSSS------PAQTTP----PTTSKTTETRASGSSAPS 1510

Query: 1567 SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTP 1626
            S P          + S+  ++  P TATS K T + P+P     T  +     S S  TP
Sbjct: 1511 STP-------GTVSLSTARTTPAPGTATSVKKTFSTPSPPPVPATSTS-----SMSTTTP 1558

Query: 1627 STHTVIT-PTHAQMATSASIHSMPT------GTIPPP----------TTLKATGSTHTAP 1669
             T  V + PT  + +TS+ +  + T      G+ P P            L+  G T    
Sbjct: 1559 GTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCES 1618

Query: 1670 TMTLTTSGTSQALSSLNTAKTSTSLHSHTSS--------------THHAEATSTSTTNIT 1715
              ++     S   + L        + SHT                 +        T N+ 
Sbjct: 1619 PRSVQCRAESFPNTPLADLGQDV-ICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVC 1677

Query: 1716 PNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS----TSTTSITP 1771
             + T    PP TV T+  +   +   T  T T+ H  ++ST  P  TS    T+T+    
Sbjct: 1678 RDITR---PPKTVATTRPTPHPTGAQTQTTFTT-HMPSASTEQPTATSRGGPTATSVTQG 1733

Query: 1772 NHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTP----ISSTGPVTATSFQTTTTYP 1827
             HT+  TR    H     +      F +  P  G       I  +G       +  T   
Sbjct: 1734 THTTPVTRN--CHPRCTWTKWFDVDFPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQ 1791

Query: 1828 --TPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKA 1885
                SHP  +    +      +       ++     Q        +     +   T    
Sbjct: 1792 CRAKSHPEVS----IEHLGQVVQCSREEGLVCRNQDQQGPFKMCLNYEVRVLCCETP--- 1844

Query: 1886 TGSTHTAPPMT--PTTSGTSQSP--SSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPK 1941
             G   T+ P+T   T SG + SP  S+ S  K+ T+    TS+T  P+      T+ T  
Sbjct: 1845 RGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTSTPQ------TSTTYA 1898

Query: 1942 HTSTGTRTPVAHTTSASSSRLPTPFTTHSPP--TGSSPFSSTGPMTATSFQTTTTYPTPS 1999
            HT++ T  P A TTSA     PT  TT + P  T S P ++  P+  TS        T S
Sbjct: 1899 HTTSTTSAPTARTTSA-----PTTRTTSASPASTTSGPGNTPSPVPTTS--------TIS 1945

Query: 2000 HPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTH 2059
             P T++ +     +TS  T ST +   T+ T   TS++  S  T T   PTT   +G   
Sbjct: 1946 APTTSITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTTSAPTTSTTSGPGT 2005

Query: 2060 TAPPMTVT 2067
            T  P+  T
Sbjct: 2006 TPSPVPTT 2013



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 139/592 (23%), Positives = 209/592 (35%), Gaps = 108/592 (18%)

Query: 1580 TGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1639
            T SSP  +T P T+   KTT T  + S   ++ P  V   ST+  TP+            
Sbjct: 1483 TSSSPAQTTPPTTS---KTTETRASGSSAPSSTPGTVS-LSTARTTPAP----------- 1527

Query: 1640 ATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALS--SLNTAKTSTSLHSH 1697
             T+ S+    +   PPP    +T S      M+ TT GTS   S  +L    TS+ L   
Sbjct: 1528 GTATSVKKTFSTPSPPPVPATSTSS------MSTTTPGTSVVSSKPTLTEPSTSSCLQEL 1581

Query: 1698 TSSTHHAEATSTST----------TNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTST 1747
             + T   + +  +            N+     +    P +V     S   +  +      
Sbjct: 1582 CTWTEWIDGSYPAPGINGGDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDV 1641

Query: 1748 SLHSHTSST------------HHPEV------TSTSTTSITPNHTSTGTRTPVAHTTSAT 1789
             + SHT               ++ E+      T      IT    +  T  P  H T A 
Sbjct: 1642 -ICSHTEGLICLNKNQLPPICYNYEIRIQCCETVNVCRDITRPPKTVATTRPTPHPTGAQ 1700

Query: 1790 SSRLPTPFTTHSPPTGT---TPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTS 1846
            +    T FTTH P   T   T  S  GP   +  Q T T P   + H    T    F   
Sbjct: 1701 TQ---TTFTTHMPSASTEQPTATSRGGPTATSVTQGTHTTPVTRNCHPRC-TWTKWFDVD 1756

Query: 1847 LVTPSTHTVIIPTHTQMATSASIHSMPTGTIP---------PPTTIKATGSTHTAPPMTP 1897
              +P  H     T+  +  S          I          P  +I+  G          
Sbjct: 1757 FPSPGPHGGDKETYNNIIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEG 1816

Query: 1898 TTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTR-TPVAHTTS 1956
                       F   K   +          P   P ++T +T   T +G   +P   T+S
Sbjct: 1817 LVCRNQDQQGPF---KMCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSS 1873

Query: 1957 ASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSF-QTTTTYPTPSHPQTTLPTHVPPFSTS 2015
               SR  T  TT +  T         P T+T++  TT+T   P+   T+ PT        
Sbjct: 1874 WQKSRTTTLVTTSTTST---------PQTSTTYAHTTSTTSAPTARTTSAPT-------- 1916

Query: 2016 LVTPSTHTVIITTHTQMATSASIHSTPTGT---VPPPTTLKATGSTHTAPPMTVTTSGTS 2072
                        T T  A+ AS  S P  T   VP  +T+ A  ++ T+ P T TTS  +
Sbjct: 1917 ------------TRTTSASPASTTSGPGNTPSPVPTTSTISAPTTSITSAPTTSTTSAPT 1964

Query: 2073 QTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTT 2124
             + +S  T + +S+  SS++  PQ S++   S+P T+      +  +PV TT
Sbjct: 1965 SSTTSAPTTSTTSAPTSSTTSSPQTSTT---SAPTTSTTSGPGTTPSPVPTT 2013



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 147/703 (20%), Positives = 233/703 (33%), Gaps = 92/703 (13%)

Query: 1731 SGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATS 1790
            +GT + R    +  T     + + ST    V+ST T S  P+   TG  +    TT+ TS
Sbjct: 1308 NGTIERRVYPCSPTTPVPPTTFSFSTPPLVVSSTHTPSNGPSSAHTGPPSSAWPTTAGTS 1367

Query: 1791 --SRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLV 1848
              +RLPT   +  P  G   + S  P    S     T          L  H      S  
Sbjct: 1368 PRTRLPTASASLPPVCGEKCLWS--PWMDVSRPGRGTDSGDFDTLENLRAHGYRVCESPR 1425

Query: 1849 TPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHT----APPMTPTTSGTSQ 1904
            +        P     A    +   P   +      +A+G  +         TP    TS 
Sbjct: 1426 SVECRAEDAPGVPLRALGQRVQCSPDVGLTCRNREQASGLCYNYQIRVQCCTPLACSTSS 1485

Query: 1905 SPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPT 1964
            SP+  +   TS +     S +  P  TP + +       ST   TP   T ++      T
Sbjct: 1486 SPAQTTPPTTSKTTETRASGSSAPSSTPGTVS------LSTARTTPAPGTATSVKKTFST 1539

Query: 1965 PFTTHSPPTGSSPFSSTGPMTAT-SFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHT 2023
            P     P T +S  S+T P T+  S + T T P+ S     L T       S   P  + 
Sbjct: 1540 PSPPPVPATSTSSMSTTTPGTSVVSSKPTLTEPSTSSCLQELCTWTEWIDGSYPAPGING 1599

Query: 2024 VIITTHTQMATSASIHSTPTGTVP------PPTTLKATGS----THTAPPMTVTTSGTSQ 2073
                T   +            +V       P T L   G     +HT   + +  +    
Sbjct: 1600 GDFDTFQNLRDEGYTFCESPRSVQCRAESFPNTPLADLGQDVICSHTEGLICLNKNQLPP 1659

Query: 2074 THSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQ-LPHLSSATTPVSTTNQLSSSFS 2132
               ++         ++          +RPP +  TT+  PH + A T  + T  + S+ +
Sbjct: 1660 ICYNYEIRIQCCETVNVC-----RDITRPPKTVATTRPTPHPTGAQTQTTFTTHMPSAST 1714

Query: 2133 PSPSAPS----TVSSYVPSSHSSPQTSS---------------PSVGTSSSFVSAPVHST 2173
              P+A S    T +S    +H++P T +               PS G          ++ 
Sbjct: 1715 EQPTATSRGGPTATSVTQGTHTTPVTRNCHPRCTWTKWFDVDFPSPGPHGG--DKETYNN 1772

Query: 2174 TLSSGS------------HSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFT 2221
             + SG                  +HP  +      +   S       R         PF 
Sbjct: 1773 IIRSGEKICRRPEEITRLQCRAKSHPEVSIEHLGQVVQCSREEGLVCRN---QDQQGPFK 1829

Query: 2222 LSALLPISTVTVSPTPSSHLASSTIAFPSTP--RTTASTHTAPAFSSQSTTSRSTSLTTR 2279
            +     +  +         + S+ +  PSTP  R  + T +  ++    TT+  T+ TT 
Sbjct: 1830 MCLNYEVRVLCCETPRGCPVTSTPVTAPSTPSGRAISPTQSTSSWQKSRTTTLVTTSTTS 1889

Query: 2280 VP-TSGFVSLTSGVTGIPTS-----PVTNLTTRHPGPTLS-----------------PTT 2316
             P TS   + T+  T  PT+     P T  T+  P  T S                 PTT
Sbjct: 1890 TPQTSTTYAHTTSTTSAPTARTTSAPTTRTTSASPASTTSGPGNTPSPVPTTSTISAPTT 1949

Query: 2317 RFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVREQQEEIT 2359
               ++  T+  S P S+  S+  T T ++P   +    Q   T
Sbjct: 1950 SITSAPTTSTTSAPTSSTTSAPTTSTTSAPTSSTTSSPQTSTT 1992


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score =  862 bits (2226), Expect = 0.0
 Identities = 471/1215 (38%), Positives = 637/1215 (52%), Gaps = 104/1215 (8%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGS---ISRIIVEL 101
            CSTWG  H+ TFD  V+ F G CNY+F+  C+ A+  F+VQLRRG  GS   ++R++++ 
Sbjct: 733  CSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYEDFNVQLRRGLVGSRPVVTRVVIKA 792

Query: 102  GASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLM 161
               V+  S   + +       LPY+  GL +   G  +++    + L L  +W  +   +
Sbjct: 793  QGLVLEASNGSVLINGQRE-ELPYSRTGLLVEQSGDYIKV---SIRLVLTFLWNGEDSAL 848

Query: 162  VLVERKYMGQMCGLCGNFDG-KVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS 220
            + ++ KY  Q CGLCG+F+G    NEF +   + L P +F  LQKLD P E C    +P 
Sbjct: 849  LELDPKYANQTCGLCGDFNGLPAFNEFYAHNAR-LTPLQFGNLQKLDGPTEQCP-DPLPL 906

Query: 221  THVRQAQHARICTQLLTLVAP---ECS--VSKEPFVLSCQADVAAAPQPGPQNSSCATLS 275
                      IC +  TL+ P   EC   V    ++ +C  D+   P        CAT  
Sbjct: 907  PAGNCTDEEGICHR--TLLGPAFAECHALVDSTAYLAACAQDLCRCP-----TCPCATFV 959

Query: 276  EYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CSSSCTFG 333
            EYSRQC+  G   R WR P LC    CP N  +QECGS C  TCSNPQ +  C   C  G
Sbjct: 960  EYSRQCAHAGGQPRNWRCPELCP-RTCPLNMQHQECGSPCTDTCSNPQRAQLCEDHCVDG 1018

Query: 334  CFCPEG---TVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTE 390
            CFCP G   TVL+D++++  C+P+ QCPC   G  Y+PG      C +C C+ G W C +
Sbjct: 1019 CFCPPGRSCTVLDDITHSG-CLPLGQCPCTHGGRTYSPGTSFNTTCSSCTCSGGLWQCQD 1077

Query: 391  RPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETS 450
             PCPG CS++GG+ ++T+D + Y  HG C+Y+L +         ++A   K G++ +E  
Sbjct: 1078 LPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCA-DSSFTVLAELRKCGLTDNENC 1136

Query: 451  LVAVVY-LSRQDKIV-ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELV 508
            L AV   L   D  + +  D  V  N     LP    NIT+F  +S  + + T  GL+L+
Sbjct: 1137 LKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQLL 1196

Query: 509  VQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA-GNC 567
            VQL P+ Q +V + P  +GQ  GLCGNFN +  DDFT   G+ E T + F ++W+A   C
Sbjct: 1197 VQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSGVVEATGAAFANTWKAQAAC 1256

Query: 568  PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEE 627
              A     DPCS+S  N+  A   CS L    + F RCH+ +NP PF+  C++  CN E 
Sbjct: 1257 ANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCNCER 1316

Query: 628  TFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTI---PCTGNTTFSYNSQACERTCLSL 684
            +   +CAAL  YVHAC+ +GV L  WR  V  CT     C  +  ++Y   AC+ TC  L
Sbjct: 1317 SEDCLCAALSSYVHACAAKGVQLSDWRDGV--CTKYMQNCPKSQRYAYVVDACQPTCRGL 1374

Query: 685  SDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVIN-GIT 743
            S+    C  S VPVDGC CP GT+LN  G CV   +CPC   G   +LA    V + G  
Sbjct: 1375 SEADVTCSVSFVPVDGCTCPAGTFLNDAGACVPAQECPCYAHGT--VLAPGEVVHDEGAV 1432

Query: 744  CHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKC 803
            C C  G+LSC          C AP  +  CS SS    GA C  +C  L  G  C  T C
Sbjct: 1433 CSCTGGKLSCLGASLQKSTGCAAPMVYLDCSNSSAGTPGAECLRSCHTLDVG--CFSTHC 1490

Query: 804  EPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTH 863
              GCVC  GL  +  G C+  E+CPC  +  +Y  G  +  DC TC+C   RW C     
Sbjct: 1491 VSGCVCPPGLVSDGSGGCIAEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRL- 1549

Query: 864  CPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVT 923
            C  TC  YG+GH ITFDG R+ F+G+CEYILA D CG N +  TF+I+TEN+ CG +G T
Sbjct: 1550 CLGTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTT 1609

Query: 924  CSRAIKIF----------------------------------LGGLSVVLADRNYTVTGE 949
            CS+AIK+F                                  L    ++L +  +     
Sbjct: 1610 CSKAIKLFVEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVAR 1669

Query: 950  EPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNM 1009
             P    G  P  +  +    +   + + + W+R  ++ IR+ +  +  +CGLCGNF+ N 
Sbjct: 1670 GPG---GDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNA 1726

Query: 1010 KDDFETRSRYVASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTF 1069
             +DF TRSR V    LE  NSWK SP C D     DPC+ N FR+SWA+++CS+++  TF
Sbjct: 1727 INDFATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTF 1786

Query: 1070 ATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPI 1129
            A C S+V    YYEACV DAC CDSGGDCEC C AVAAYAQAC D G+CV WRTP  CP+
Sbjct: 1787 AACRSQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCVSWRTPDTCPL 1846

Query: 1130 YCGFYNTHTQDGHGEYQYTQEANCTWHYQPC------LC--PSQPQSVPGSNIEGCY-NC 1180
            +C FYN H               C WHYQPC       C  PS    V    +EGCY  C
Sbjct: 1847 FCDFYNPH-------------GGCEWHYQPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKC 1893

Query: 1181 SQDE-YFDHEEGVCV 1194
               + +F+ ++  CV
Sbjct: 1894 PPSQPFFNEDQMKCV 1908



 Score =  365 bits (937), Expect = e-100
 Identities = 210/566 (37%), Positives = 306/566 (54%), Gaps = 23/566 (4%)

Query: 45  CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGS---ISRIIVEL 101
           CSTWG+ H+ TFD  V+ F G CNY+F+  C  A+  F++QLRR  + +   +SR+++++
Sbjct: 81  CSTWGSFHYKTFDGDVFRFPGLCNYVFSEHCGAAYEDFNIQLRRSQESAAPTLSRVLMKV 140

Query: 102 GASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLM 161
              V+ +++  + V    V+ LP++ +G+ I    QS      +  L L ++W  D  L+
Sbjct: 141 DGVVIQLTKGSVLVNGHPVL-LPFSQSGVLIQ---QSSSYTKVEARLGLVLMWNHDDSLL 196

Query: 162 VLVERKYMGQMCGLCGNFDGK-VTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS 220
           + ++ KY  + CGLCG+F+G  V +E +S   K L P +F  LQK+DDP E C    +P 
Sbjct: 197 LELDTKYANKTCGLCGDFNGMPVVSELLSHNTK-LTPMEFGNLQKMDDPTEQCQ-DPVPE 254

Query: 221 THVRQAQHARICTQLL---TLVAPECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEY 277
                +    IC +LL           V    ++ +C+ D+         +  C TL+EY
Sbjct: 255 PPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLCFCEDTDLLSCVCHTLAEY 314

Query: 278 SRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CSSSCTFGCF 335
           SRQC+  G   + WR P  C   +CP N  Y EC S C  TCSN +HS  C   C  GCF
Sbjct: 315 SRQCTHAGGLPQDWRGPDFCPQ-KCPNNMQYHECRSPCADTCSNQEHSRACEDHCVAGCF 373

Query: 336 CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPG 395
           CPEGTVL+D+     CVPV++C CV +GA YAPG      C  C C+ GRW C E PCPG
Sbjct: 374 CPEGTVLDDIGQTG-CVPVSKCACVYNGAAYAPGATYSTDCTNCTCSGGRWSCQEVPCPG 432

Query: 396 HCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVV 455
            CS+ GG+  +TFD + Y  HG C+Y+L + P       ++A   + G++ SET L +V 
Sbjct: 433 TCSVLGGAHFSTFDGKQYTVHGDCSYVLTK-PCDSSAFTVLAELRRCGLTDSETCLKSVT 491

Query: 456 YL--SRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRP 513
                 Q  +VI     V  N     LP    N+T+FR ++  +   TS GL+L +QL P
Sbjct: 492 LSLDGAQTVVVIKASGEVFLNQIYTQLPISAANVTIFRPSTFFIIAQTSLGLQLNLQLVP 551

Query: 514 IFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA-GNCPAALE 572
             Q ++ + P+ RGQT GLCGNFN    DDF T  G+ E TA+ F ++++    CP    
Sbjct: 552 TMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSGVVEATAAAFFNTFKTQAACPNIRN 611

Query: 573 RETDPCSMSQLN--KVCAETHCSMLL 596
              DPCS+S  N  ++ A + C  L+
Sbjct: 612 SFEDPCSLSVENAPRMGAPSACRTLV 637



 Score =  287 bits (734), Expect = 1e-76
 Identities = 365/1262 (28%), Positives = 523/1262 (41%), Gaps = 196/1262 (15%)

Query: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTS 1261
            P  P T    T  S P   W +T  +TT     STG +       A+P+ TP     LT 
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGST-------ATPSSTPGTTWILTE 4252

Query: 1262 SKPTASSGEPPRPT-TAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTST 1320
               TA+   P   T TA + QAT+G P  +T   TAT PTVT +     A+  S   T+T
Sbjct: 4253 PSTTATVTVPTGSTATASSTQATAGTPHVST---TATTPTVTSSK----ATPFSSPGTAT 4305

Query: 1321 AQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQP 1380
            A    R+T T PT     TS T   S++     T  +QTT P  T ++ T  +TP+    
Sbjct: 4306 ALPALRSTATTPT----ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHT 4361

Query: 1381 TRPTATETTQTRTT----TEYTTPQTPHTTHSPPTAGSP---VPSTGPVTATS---FHAT 1430
            +    T  T TR T    T  +TP T HTT  P T  +     PS+ P TA +   + +T
Sbjct: 4362 STVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIST 4421

Query: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTL 1490
            TT PT S   T  P+ VP       T  T TV+T T   +AT +           P ++ 
Sbjct: 4422 TTTPTTSG-STVTPSSVPG------TTHTPTVLTTTTTTVATGSM--------ATPSSST 4466

Query: 1491 KATGSTHTAPPI---TPTTSGTSQAHSSFSTNKTP-TSLHSHTSSTHHPEVTPTSTTTIT 1546
            + +G+THT PP+   T TT G S + SS  T +T  TS  S T  T H    P++ T+ T
Sbjct: 4467 QTSGTTHT-PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI-TEPSTGTSHT 4524

Query: 1547 PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPT------GSSPFSSTGPMTATSFKTTT 1600
            P  T+  T+    H+  A SS  P   TT SPP+      G +  +S    TAT  KT T
Sbjct: 4525 PAATTGTTQ----HSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRT 4580

Query: 1601 TYPTPSHPQTTLPTHV------PPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIP 1654
            +   PS P +   T V      P  + S     ++ +  P+     T ++I +       
Sbjct: 4581 STLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCE 4640

Query: 1655 PPTTLKATGSTHTAPTMTLTTSGTSQALS------------------------------- 1683
             P  L+        P + L   G     S                               
Sbjct: 4641 QPLGLECRAQAQ--PGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNY 4698

Query: 1684 ---SLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSF 1740
                   A +ST++ S T  T       T+T   T +  ST TP  T  T+   +  +S 
Sbjct: 4699 GHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSP 4758

Query: 1741 STAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTH 1800
            +T  T+TS  + +SS       S  T +  P  TST T++     T   SS L T     
Sbjct: 4759 ATTPTATSSKATSSS-------SPRTATTLPVLTSTATKSTATSVTPIPSSTLGT----- 4806

Query: 1801 SPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTH------VPSFSTSLVTPSTHT 1854
               TGT P  +T PV   S    ++ P  +H  T L T         S ST   TP T  
Sbjct: 4807 ---TGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTW 4863

Query: 1855 VIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914
            ++    T++ T+A             TT  ATG T T P  TP   GT+   +  +T  T
Sbjct: 4864 IL----TELTTAA-------------TTTAATGPTAT-PSSTP---GTTWILTELTTTAT 4902

Query: 1915 STSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSR----LPTPFTTHS 1970
            +T+    T ST  P  TP +T  +T   T+     P   T +ASS++     P   TT +
Sbjct: 4903 TTA---STGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTAT 4959

Query: 1971 PPTGSS----PFSSTGPMTA-TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI 2025
             PT +S    P SS G  TA  + ++T T PT      T  T +P  S+SL T  T    
Sbjct: 4960 TPTVTSSKATPSSSPGTATALPALRSTATTPT-----ATSFTAIP--SSSLGTTWTRLSQ 5012

Query: 2026 ITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQT-HSSFSTATAS 2084
             TT T   ++A+  STP  TV   T L AT +T  A     T S T  T H++    T +
Sbjct: 5013 TTTPTATMSTATPSSTPE-TVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTT 5071

Query: 2085 SSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV--- 2141
            + F           ++ P SSP T   P     TTP+ST + + +S +P  +  STV   
Sbjct: 5072 TGF-----------TATPSSSPGTALTP---PTTTPMSTMSTIHTSSTPETTHTSTVLTT 5117

Query: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVS-APVHSTTLSSGSHSSLSTHPTTASVSASPLFPS 2200
            ++ +  + +S  T S ++GT+          +TT ++GS ++LS+ P T  +   P   +
Sbjct: 5118 TATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIA 5177

Query: 2201 S---PAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTAS 2257
            +   P  ST   ++   T  +P  ++ +  + T T S  PS    SST+    TP    S
Sbjct: 5178 TVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPS----SSTVGTTRTPAVLPS 5233

Query: 2258 THTAPAFSSQSTTSRSTSLTTRVPTSGFVS----LTSGVTGIPTSPVTNLTTRHPGPTLS 2313
            +    + S+ S++  +T   T  P+S F +       G    P   + N T R  G    
Sbjct: 5234 SLPTFSVSTVSSSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDR-AGCHFY 5292

Query: 2314 PTTRFLTSSLTAHGSTPAS-APVSSLGTPTPTSPGVCSVREQQEEITFKGCMANVTVTRC 2372
                         G+ P S  PVSS    +P+    C       ++     + N TV RC
Sbjct: 5293 AVCNQHCDIDRFQGACPTSPPPVSSAPLSSPSPAPGCDNAIPLRQVNETWTLENCTVARC 5352

Query: 2373 EG 2374
             G
Sbjct: 5353 VG 5354



 Score =  270 bits (689), Expect = 2e-71
 Identities = 356/1332 (26%), Positives = 526/1332 (39%), Gaps = 232/1332 (17%)

Query: 1201 TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLT 1260
            T  P  T    T  S P  V   T  +TT     +TG   + + TP +   T +L  T T
Sbjct: 3193 TTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTT 3252

Query: 1261 ------SSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTAS 1314
                  SS P  +   P   +T  TP         +++  T   PTV   TT  T +T S
Sbjct: 3253 GFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTT-TTVATGS 3311

Query: 1315 PATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTT 1374
             AT S++  T+ TT T P P T+ T  T  +S +   P T  T  T        TT  T 
Sbjct: 3312 MATPSSSTQTSGTTHTPPVPNTTAT--THGRSLSPSSPHTVRTAWTSATSGTLGTTHITE 3369

Query: 1375 PQPGQPTRPTATETTQTRTTTEYTTPQ-TPHTTHSPPTAGSPVPSTGPVTATSFHATTTY 1433
            P  G    P AT  T   +T   ++P  +  TT SPP+ G+  P  G   ATS    T  
Sbjct: 3370 PSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP--GHTRATSRTTATAT 3427

Query: 1434 PTPSHPETTLPTHVPPFSTSLVTPST----------------HTVITPTHAQMATSASNH 1477
            P+ +   T LP+   P S  + T  T                + +  P+     T ++  
Sbjct: 3428 PSKTRTSTLLPSS--PTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 3485

Query: 1478 SAPTGTIPPPTTLKATGSTHTAPPITPTTSGT--SQAHSSFSTNKTPTS---------LH 1526
            +A       P  L+         P+         S        N+             + 
Sbjct: 3486 AAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIR 3545

Query: 1527 SHTSSTHHPEVTPTSTTTITPNPTSTRT-----RTPVAHTNSATSS----------RPPP 1571
                +  H   TP +++T TP+ T   T     +T  A T + T S           PPP
Sbjct: 3546 VFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPP 3605

Query: 1572 PFTTHS----PPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPS 1627
               T +      T S   SS+ P TAT+    T+  T S    T  T +P F+      +
Sbjct: 3606 KVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKS--TATSFTPIPSFTLG----T 3659

Query: 1628 THTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTL----TTSGTSQALS 1683
            T T+   T   MAT ++IH   T      +T+  T +T T  T ++    +T GT+  L+
Sbjct: 3660 TGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILT 3719

Query: 1684 SLNTAKTSTSLHSHTSSTHHAEATS------TSTTNITPNPTSTGTPPMTVTTSGTSQSR 1737
             L TA T+T+    T++      T+      ++T  +T    ST T   T  T+GT +  
Sbjct: 3720 ELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVL 3779

Query: 1738 SSFSTAKTSTSLHSHTSS-----THHPEVTSTSTTSITPNHTS-------------TGTR 1779
            +S +T  T  S  +  SS     T  P + ST+TT    + T+             + T 
Sbjct: 3780 TSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3839

Query: 1780 TPVAHTTSATSSRLP---------TPFTTHSPPTGT--TPISSTGPVTATSFQTTTT--- 1825
            TP A  ++AT S  P         T  TT +  TG+  TP S+ G    T   TTTT   
Sbjct: 3840 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 3899

Query: 1826 YPTP-SHPHTTL-------PTHVPSFSTSLVTPSTHTVIIP--THTQMATSASIHSMPTG 1875
              TP S P T L        T  P+   S VTPS+    IP  THT    + +  ++ TG
Sbjct: 3900 TATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSS----IPGTTHTATVLTTTTTTVATG 3955

Query: 1876 TI-PPPTTIKATGSTHT--APPMTPTTSGTSQSPSSFSTAKTS-TSLPYHTSSTHHPEVT 1931
            ++  P ++ + +G+THT   P  T TT G S  PSS  T +T+ TS       T H  +T
Sbjct: 3956 SMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTH--IT 4013

Query: 1932 PTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST-GPMTATSFQ 1990
              ST      HT   T +   H+T A SS  P+  TT SPP   SP ++T G    TS  
Sbjct: 4014 EPSTVT---SHTPAATTSTTQHSTPALSSPHPSSRTTESPP---SPGTTTPGHTRGTSRT 4067

Query: 1991 TTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP- 2049
            T T  P+ +   T LP        S  T +  T ++TT  +   + S     +  +P P 
Sbjct: 4068 TATATPSKTRTSTLLP--------SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS 4119

Query: 2050 -------TTLKATGSTHTAPPMTVTTSGTSQTH--------------------------- 2075
                   + ++A G      P+ +     +Q                             
Sbjct: 4120 GGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVG 4179

Query: 2076 -----SSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSS 2130
                  ++       ++    S    +S++ P S+P TT +  L+  TT  +TT    S+
Sbjct: 4180 KFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWI--LTKLTTTATTTESTGST 4237

Query: 2131 FSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTA 2190
             +PS +  +T     PS+ ++    + S  T+SS         T  +   S+ +T PT  
Sbjct: 4238 ATPSSTPGTTWILTEPSTTATVTVPTGSTATASS------TQATAGTPHVSTTATTPTVT 4291

Query: 2191 SVSASPLFPSSPAASTTI-----RATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
            S  A+P   SSP  +T +      AT P   S     S+ L  +   +S T +     ST
Sbjct: 4292 SSKATPF--SSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMST 4349

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRS------------TSLTTRVP---TSGFVSLTS 2290
                STP T    HT+   ++ +TT+R+            T+ TT+VP   T+GF    S
Sbjct: 4350 ATPSSTPET---AHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPS 4406

Query: 2291 GVTG----------IPTSPVTNLTT----RHPGPTLSPTTRFLTSSLTAHGS--TPASAP 2334
               G            T+P T+ +T      PG T +PT    T++  A GS  TP+S+ 
Sbjct: 4407 SSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSST 4466

Query: 2335 VSSLGTPTPTSP 2346
             +S  T TP  P
Sbjct: 4467 QTSGTTHTPPVP 4478



 Score =  269 bits (688), Expect = 2e-71
 Identities = 350/1185 (29%), Positives = 499/1185 (42%), Gaps = 205/1185 (17%)

Query: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTS 1261
            P  P T       S P   W +T  +TT     STG +       A+P+ TP     LT 
Sbjct: 3053 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGST-------ATPSSTPGTTWILTE 3105

Query: 1262 SKPTASSGEPPRPT-TAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTST 1320
               TA+   P   T TA + QAT+G P  +T   TAT PTVT +     A+  S   T+T
Sbjct: 3106 PSTTATVTVPTGSTATASSTQATAGTPHVST---TATTPTVTSSK----ATPFSSPGTAT 3158

Query: 1321 AQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQP 1380
            A    R+T T PT     TS T   S++     T  +QTT P  T ++ T  +TP+    
Sbjct: 3159 ALPALRSTATTPT----ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE---- 3210

Query: 1381 TRPTATETTQTRTTTEYT--------TPQTPHTTH---SPPTAGSPVPSTGPVTATS--- 1426
            T  T+T  T T TTT  T        TP T HTT    +  T  +  PS+ P TA +   
Sbjct: 3211 TVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPV 3270

Query: 1427 FHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPP 1486
            + +TTT PT +   T  P+ +P       T  T TV+T T   +AT +           P
Sbjct: 3271 WISTTTTPT-TRGSTVTPSSIPG------TTHTPTVLTTTTTTVATGS--------MATP 3315

Query: 1487 PTTLKATGSTHT--APPITPTTSGTSQAHSSFSTNKTP-TSLHSHTSSTHHPEVTPTSTT 1543
             ++ + +G+THT   P  T TT G S + SS  T +T  TS  S T  T H    P++ T
Sbjct: 3316 SSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTH-ITEPSTGT 3374

Query: 1544 TITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSST-GPMTATSFKTTTTY 1602
            + TP  T+  T+    H+  A SS  P   TT SPP   SP ++T G   ATS  T T  
Sbjct: 3375 SHTPAATTGTTQ----HSTPALSSPHPSSRTTESPP---SPGTTTPGHTRATSRTTATAT 3427

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPST----------------HTVITPTHAQMATSASIH 1646
            P+ +   T LP+   P S  + T  T                + +  P+     T ++I 
Sbjct: 3428 PSKTRTSTLLPS--SPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIR 3485

Query: 1647 SMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALS-----------SLNTAKTSTSLH 1695
            +        P  L+        P + L   G     S            +   K   +  
Sbjct: 3486 AAGGAVCEQPLGLECRAQAQ--PGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYE 3543

Query: 1696 SHTSSTHHAEATSTSTTNITPNPTST-GTPPMTVTTSGTSQSRSSFSTAKT-STSLHSHT 1753
                  ++    ST  T+ T  P+ST GT     T   T Q+ ++ +TA T ST++ S T
Sbjct: 3544 IRVFCCNYGHCPSTPATSSTATPSSTPGT-----TWILTEQTTAATTTATTGSTAIPSST 3598

Query: 1754 SSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTG 1813
              T  P    TST +           TP A ++ ATSS  P   TT    T T   S   
Sbjct: 3599 PGTAPPPKVLTSTAT-----------TPTATSSKATSSSSPRTATTLPVLTSTATKS--- 3644

Query: 1814 PVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMP 1873
              TATSF                 T +PSF+      +T T+   T T MAT ++IH   
Sbjct: 3645 --TATSF-----------------TPIPSFTLG----TTGTLPEQTTTPMATMSTIHPSS 3681

Query: 1874 TGTIPPPTTI---KATGSTHTAPPMTP-TTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPE 1929
            T      +T+   KAT +  T+   TP +T GT+   +  +TA T+T+    T  T  P 
Sbjct: 3682 TPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAA---TGPTATPS 3738

Query: 1930 VTPTSTTNITPKHTSTGTRTPVAHTTSASSSR-----LPTPFTTHSPPT--GSSPFSSTG 1982
             TP +T  +T   T+     P   T +ASS+R     L    +T + PT   S    S+ 
Sbjct: 3739 STPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSS 3798

Query: 1983 PMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTP 2042
            P TAT+     +  T + P  T  T +P  S+SL T  T     TT T   ++A+  STP
Sbjct: 3799 PGTATALPALRS--TATTPTATSVTAIP--SSSLGTAWTRLSQTTTPTATMSTATPSSTP 3854

Query: 2043 TGTVPPPTTLKATGSTHTAPPMTVTTSGTSQT-HSSFSTATASSSFISSSSWLPQNSSSR 2101
              TV   T L  T +T  A     T S T  T H++    T ++ F           ++ 
Sbjct: 3855 E-TVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF-----------TAT 3902

Query: 2102 PPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT 2161
            P SSP T   P +  +TT   TT    S+ +PS S P T  +    + ++   ++ S+ T
Sbjct: 3903 PSSSPGTALTPPVWISTTTTPTTR--GSTVTPS-SIPGTTHTATVLTTTTTTVATGSMAT 3959

Query: 2162 SSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFT 2221
             S        S+T +SG+  +     TTA+     L PSSP           HT+ + +T
Sbjct: 3960 PS--------SSTQTSGTTHTPPVPNTTATTHGRSLPPSSP-----------HTVRTAWT 4000

Query: 2222 --LSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSL--T 2277
               S +L  + +T   T +SH  ++T        T+ + H+ PA SS   +SR+T    +
Sbjct: 4001 SATSGILGTTHITEPSTVTSHTPAAT--------TSTTQHSTPALSSPHPSSRTTESPPS 4052

Query: 2278 TRVPTSGFVSLTSGVTGIPTSPVTNLTTRHP-GPTLSPTTRFLTS 2321
                T G    TS  T   T   T  +T  P  PT +P T  +T+
Sbjct: 4053 PGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 4097



 Score =  260 bits (665), Expect = 1e-68
 Identities = 339/1269 (26%), Positives = 504/1269 (39%), Gaps = 205/1269 (16%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPAS-PTQTPLLPAT 1258
            T P+  TTP    +   P+     T TST +   ++T  + SS  TP+S P  T +L   
Sbjct: 3662 TLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTEL 3721

Query: 1259 LTSSKPTASSGEPPRPTTAVTPQATSGL--PPTATLRSTATKPTVTQATTRATAST---- 1312
             T++  TA++G  P  T + TP  T  L  P T    +  T  T T ++TRATA T    
Sbjct: 3722 TTAATTTAATG--PTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVL 3779

Query: 1313 ASPATTSTAQSTTRTTMTLPTPATS------------GTSPTLPKSTNQELPGTTATQTT 1360
             S ATT T  S+  T  + P  AT+             TS T   S++     T  +QTT
Sbjct: 3780 TSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3839

Query: 1361 GPRPTPASTTGPTTPQPGQPTRPTATETTQTRTT----TEYTTPQTPHTTHSPPTAGS-- 1414
             P  T ++ T  +TP+    +    T TT TR T    T  +TP T HTT  P T  +  
Sbjct: 3840 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 3899

Query: 1415 -PVPSTGPVTATS---FHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1470
               PS+ P TA +   + +TTT PT +   T  P+ +P  +T   T  T T  T     M
Sbjct: 3900 TATPSSSPGTALTPPVWISTTTTPT-TRGSTVTPSSIPG-TTHTATVLTTTTTTVATGSM 3957

Query: 1471 AT--SASNHSAPTGTIPPPTTLKAT-------------------------GSTHTAPPIT 1503
            AT  S++  S  T T P P T   T                         G+TH   P T
Sbjct: 3958 ATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST 4017

Query: 1504 PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNS 1563
              TS T  A +S + + TP     H SS      +P S  T TP  T   +RT    T S
Sbjct: 4018 -VTSHTPAATTSTTQHSTPALSSPHPSS--RTTESPPSPGTTTPGHTRGTSRTTATATPS 4074

Query: 1564 ATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSL 1623
             T +    P +  S P  +   +   P  A S     +YP P                  
Sbjct: 4075 KTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPG----------------- 4117

Query: 1624 VTPSTHTVITPTHAQMATSASIHSMPTG-----TIPPPTTLKATGSTHTAPTMTLTTSGT 1678
              PS     T ++ + A   ++   P G        P   L+  G        +L     
Sbjct: 4118 --PSGGDFDTYSNIR-AAGGAVCEQPLGLECRAQAQPGVPLRELGQ---VVECSLDFGLV 4171

Query: 1679 SQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMT-VTTSGTSQSR 1737
             +    +   K   +        ++    ST  T+ T  P+S  TP  T + T  T+ + 
Sbjct: 4172 CRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSS--TPGTTWILTKLTTTAT 4229

Query: 1738 SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPF 1797
            ++ ST  T+T   +  ++    E ++T+T ++    T+T + T     T   S+   TP 
Sbjct: 4230 TTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT 4289

Query: 1798 TTHSPPTGTTPISSTGPVTA-TSFQTTTTYPTPSH----------------PHTTLPTHV 1840
             T S     TP SS G  TA  + ++T T PT +                   TT PT  
Sbjct: 4290 VTSSK---ATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT 4346

Query: 1841 PSFSTSLVTPST-HTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTT 1899
             S +T   TP T HT  + T T   T A      TG++  P++    G+ HT    T TT
Sbjct: 4347 MSTATPSSTPETAHTSTVLTTTATTTRA------TGSVATPSS--TPGTAHTTKVPTTTT 4398

Query: 1900 SGTSQSPSSF-STAKT------STSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVA 1952
            +G + +PSS   TA+T      +T+ P  + ST  P   P +T   TP   +T T T   
Sbjct: 4399 TGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTH--TPTVLTTTTTTVAT 4456

Query: 1953 HTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPF 2012
             + +  SS   T  TTH+PP  ++  ++ G   + S   T      S    TL T     
Sbjct: 4457 GSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGT----- 4511

Query: 2013 STSLVTPSTHTVIITTHTQMATSASI-HSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGT 2071
             T +  PST     T+HT  AT+ +  HSTP  + P P++      T  +PP   TT+  
Sbjct: 4512 -THITEPSTG----TSHTPAATTGTTQHSTPALSSPHPSS-----RTTESPPSPGTTTPG 4561

Query: 2072 SQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT--------------QLPHLSSA 2117
              T +S +TATA+ S   +S+ LP + +S P ++ +TT                P    +
Sbjct: 4562 HTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS 4621

Query: 2118 TTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQ-----------------TSSPSVG 2160
                 T + + ++       P  +     +    P                   +   VG
Sbjct: 4622 GGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVG 4681

Query: 2161 TSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASP----LFPSSPAASTTIRATLPHTI 2216
                  +  +     + G   S     +TA  S++P    +       +TT  +T   + 
Sbjct: 4682 KFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTAST--GST 4739

Query: 2217 SSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSL 2276
            ++P +     P   V  SP  +    SS     S+PRT     T P  +S +T S +TS+
Sbjct: 4740 ATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTAT---TLPVLTSTATKSTATSV 4796

Query: 2277 TTRVPTSGFVSLTSGVTGI----PTSPVTNLTTRHPGPTLSP-------TTRFLTSSLTA 2325
            T  +P+S     T G TG      T+PV  ++T HP  T          TT+  T+  T+
Sbjct: 4797 TP-IPSS-----TLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATS 4850

Query: 2326 HGSTPASAP 2334
              STP+S P
Sbjct: 4851 STSTPSSTP 4859



 Score =  250 bits (638), Expect = 1e-65
 Identities = 351/1279 (27%), Positives = 512/1279 (40%), Gaps = 151/1279 (11%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTG-TSTTIGLLSSTGPSPSSNHTPASPTQTP 1253
            P    TT  P T     T  S P      T  T+TT  + + +  +PSS+   +  T TP
Sbjct: 3914 PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTP 3973

Query: 1254 LLPATLTSSKPTASSGEPPRPTTAVTPQATSGL--------PPTATLRSTATKPTVTQAT 1305
             +P T  ++   +     P         ATSG+        P T T  + A   + TQ +
Sbjct: 3974 PVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHS 4033

Query: 1306 T----------RATASTASPATTSTAQS--TTRTTMTLPTPATSGTSPTLPKSTNQELPG 1353
            T          R T S  SP TT+   +  T+RTT T  TP+ + TS  LP S       
Sbjct: 4034 TPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATA-TPSKTRTSTLLPSSPTSAPIT 4092

Query: 1354 TTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAG 1413
            T  T    P+   +     + P PG       T +                   +    G
Sbjct: 4093 TVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPG 4152

Query: 1414 SPVPSTGPVTATSFHATTTYPTPSHP-------ETTLPTHVPPFSTSLVTPSTHTVITPT 1466
             P+   G V   S                       +      +     TP+T +  TP+
Sbjct: 4153 VPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPS 4212

Query: 1467 HAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLH 1526
                 T        T T     T ++TGST T P  TP T+      S+ +T   PT   
Sbjct: 4213 STPGTTWILTKLTTTAT-----TTESTGSTAT-PSSTPGTTWILTEPSTTATVTVPTGST 4266

Query: 1527 SHTSSTHHPEVTP-TSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS-- 1583
            +  SST     TP  STT  TP  TS++  TP +   +AT+   P   +T + PT +S  
Sbjct: 4267 ATASSTQATAGTPHVSTTATTPTVTSSKA-TPFSSPGTATAL--PALRSTATTPTATSFT 4323

Query: 1584 --PFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFS-TSLVTPSTHTVITPTHAQMA 1640
              P SS G       +TTT   T S   T  P+  P  + TS V  +T T    T +   
Sbjct: 4324 AIPSSSLGTTWTRLSQTTTPTATMS---TATPSSTPETAHTSTVLTTTATTTRATGSVAT 4380

Query: 1641 TSASIHSMPTGTIPPPTTLKAT-------GSTHTAP-----TMTLTTSGTSQALSSL-NT 1687
             S++  +  T  +P  TT   T       G+  T P     T T TTSG++   SS+  T
Sbjct: 4381 PSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGT 4440

Query: 1688 AKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPM---TVTTSGTSQSRSSFSTAK 1744
              T T L   T++T  A  +  + ++ T    +T TPP+   T TT G S S SS  T +
Sbjct: 4441 THTPTVLT--TTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVR 4498

Query: 1745 TS-TSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPP 1803
            T+ TS  S T  T H    ST T+     HT   T     H+T A SS  P+  TT SPP
Sbjct: 4499 TAWTSATSGTLGTTHITEPSTGTS-----HTPAATTGTTQHSTPALSSPHPSSRTTESPP 4553

Query: 1804 T-GTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQ 1862
            + GTT   + G  TATS  T T  P+ +   T LP+   S       P T  V      Q
Sbjct: 4554 SPGTT---TPGHTTATSRTTATATPSKTRTSTLLPSSPTS------APITTVVTTGCEPQ 4604

Query: 1863 MATSASI---HSMPT---GTIPPPTTIKATGSTHTAPPMTPTTSGTSQS--PSSFSTAKT 1914
             A S  +   + MP    G     + I+A G      P+       +Q   P        
Sbjct: 4605 CAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVV 4664

Query: 1915 STSLPYHTSSTHHPEVTPTSTT-----NITPKHTSTGTRTPVAHTTSASSSRLPTPFTTH 1969
              SL +     +  +V            +   +      TP   +T+  SS   T +   
Sbjct: 4665 ECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILT 4724

Query: 1970 SPPTGSSPFSSTGPMTATSFQTTTTYPTP---SHPQTTLPTHVPPFSTSLVTPSTHTVII 2026
               T ++  +STG  TAT   T  T P P   + P TT PT     +TS  +P T T + 
Sbjct: 4725 ELTTTATTTASTGS-TATPSSTPGTAPPPKVLTSPATT-PTATSSKATSSSSPRTATTL- 4781

Query: 2027 TTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQT-HSSFSTATASS 2085
                 + TS +  ST T   P P++    G+T T P  T T   T  T H S +  T  +
Sbjct: 4782 ----PVLTSTATKSTATSVTPIPSS--TLGTTGTLPEQTTTPVATMSTIHPSSTPETTHT 4835

Query: 2086 SFI---SSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVS 2142
            S +    +++    +S+S P S+P TT +  L+  TT  +TT     + +PS S P T  
Sbjct: 4836 STVLTTKATTTRATSSTSTPSSTPGTTWI--LTELTTAATTTAATGPTATPS-STPGT-- 4890

Query: 2143 SYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPT--TASVSASPLFPS 2200
            +++ +  ++  T++ S G++++  S P  +  L+  S ++  T PT  TA+ S++     
Sbjct: 4891 TWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAG 4950

Query: 2201 SPAASTTIRATLPHTISS-------PFTLSALLPISTVTVSPT-------PSSHLASSTI 2246
            +P  STT  AT P   SS       P T +AL  + +   +PT       PSS L ++  
Sbjct: 4951 TPHVSTT--ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT 5008

Query: 2247 AFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTR 2306
                T   TA+  TA   S+  T   ST LT         + T+G TG   +P +   T 
Sbjct: 5009 RLSQTTTPTATMSTATPSSTPETVHTSTVLTA-------TATTTGATGSVATPSSTPGTA 5061

Query: 2307 HPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSV--REQQEEITFKGCM 2364
            H       TT+  T++ T   +TP+S+P ++L  PT T     S        E T    +
Sbjct: 5062 H-------TTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTV 5114

Query: 2365 --ANVTVTRCEGACISAAS 2381
                 T+TR   +  + +S
Sbjct: 5115 LTTTATMTRATNSTATPSS 5133



 Score =  245 bits (626), Expect = 3e-64
 Identities = 335/1247 (26%), Positives = 492/1247 (39%), Gaps = 167/1247 (13%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPL 1254
            P    +T  P +TP+   T +  T     TG + ++   SST   P + HT   PT T  
Sbjct: 2694 PTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSST---PGTAHTTKVPTTTTT 2750

Query: 1255 LPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTAS 1314
                  SS P  +   P   +T  TP         +++  T    TV   TT  T +T S
Sbjct: 2751 GFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVL-TTTTTTVATGS 2809

Query: 1315 PATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTT 1374
             AT S++  T+ TT T P P T  T  T  +S     P T  T  T        TT  T 
Sbjct: 2810 MATPSSSTQTSGTTHTPPVPNTMAT--THGRSLPPSSPHTVRTAWTSATSGILGTTHIT- 2866

Query: 1375 PQPGQPTRPTATETTQTRTTTEYTTP--QTPH----TTHSPPTAGSPVPSTGPVTATSFH 1428
                +P+  T+     T  TT+++TP   +PH    TT SPP+ G+  P  G  TATS  
Sbjct: 2867 ----EPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP--GHTTATSRT 2920

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPST----------------HTVITPTHAQMAT 1472
              T  P+ +   T LP+   P S  + T  T                + +  P+     T
Sbjct: 2921 TATATPSKTRTSTLLPS--SPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDT 2978

Query: 1473 SASNHSAPTGTIPPPTTLKATGSTHTAPPITP--TTSGTSQAHSSFSTNKTPT------- 1523
             ++  +A       P  L+         P+         S        N+          
Sbjct: 2979 YSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCF 3038

Query: 1524 --SLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTG 1581
               +     +  H   TP +++T  P+ T   T      T +AT++      +T S  T 
Sbjct: 3039 NYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTE-----STGSTATP 3093

Query: 1582 SSPFSSTGPMTATSFKTTTTYPTPS---HPQTTLPTHVPPFSTSLVTPS-THTVITPTHA 1637
            SS   +T  +T  S   T T PT S      T      P  ST+  TP+ T +  TP  +
Sbjct: 3094 SSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSS 3153

Query: 1638 QMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSH 1697
                +A      T T P  T+  A       P+ +L T+ T  + ++  TA  ST+  S 
Sbjct: 3154 PGTATALPALRSTATTPTATSFTA------IPSSSLGTTWTRLSQTTTPTATMSTATPSS 3207

Query: 1698 TSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTH 1757
            T  T H     T+T   T    S  TP  T  T+ T++  ++ +T  T+T   S  ++  
Sbjct: 3208 TPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTART 3267

Query: 1758 HPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTA 1817
             P   ST+TT  T   T T +  P    T+ T + L T  TT +  +  TP SST     
Sbjct: 3268 LPVWISTTTTPTTRGSTVTPSSIP---GTTHTPTVLTTTTTTVATGSMATPSSST----- 3319

Query: 1818 TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI 1877
               QT+ T  TP  P+TT  TH  S S S    S HTV         TSA+  ++ T  I
Sbjct: 3320 ---QTSGTTHTPPVPNTTATTHGRSLSPS----SPHTV-----RTAWTSATSGTLGTTHI 3367

Query: 1878 PPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYH--TSSTHHPEVTPTST 1935
              P    +TG++HT    T TT  ++ + SS   +  +T  P    T++  H   T  +T
Sbjct: 3368 TEP----STGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTT 3423

Query: 1936 TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPP--TGSSPFSSTGPMTATSFQTTT 1993
               TP  T T T  P    +S +S+ + T  T    P    S     + PM   S     
Sbjct: 3424 ATATPSKTRTSTLLP----SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFD 3479

Query: 1994 TY-------------PTPSHPQTTLPTHVPPFSTSLVTPST--HTVIITTHTQMAT---- 2034
            TY             P     +      VP      V   +    ++     Q+      
Sbjct: 3480 TYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMC 3539

Query: 2035 ---SASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSS 2091
                  +     G  P      +T +  + P  T     T QT ++ +TAT  S+ I SS
Sbjct: 3540 FNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWIL--TEQTTAATTTATTGSTAIPSS 3597

Query: 2092 SWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSP----------SPSAPSTV 2141
            +       + PP   +T      S+ATTP +T+++ +SS SP          S +  ST 
Sbjct: 3598 T-----PGTAPPPKVLT------STATTPTATSSKATSSSSPRTATTLPVLTSTATKSTA 3646

Query: 2142 SSY--VPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSS--LSTHPTTASVSASPL 2197
            +S+  +PS       + P   T+     + +H ++    +H+S  L+T  TT   ++S  
Sbjct: 3647 TSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMS 3706

Query: 2198 FPSS-----------PAASTTIRATLPHTI--SSPFTLSALL-PISTVTVS-PTPSSHLA 2242
             PSS             A+TT  AT P     S+P T   L  P +T TV+ PT S+  A
Sbjct: 3707 TPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATA 3766

Query: 2243 SSTIAFPSTPRTTASTHTAP-AFSSQSTTSRSTSLTTRVPTSGFVSLT---SGVTGIPTS 2298
            SST A   T +   ST T P   SS++T S S    T +P     + T   + VT IP+S
Sbjct: 3767 SSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSS 3826

Query: 2299 PVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
             +    TR    T +PT    T S     STP +   S++ T T T+
Sbjct: 3827 SLGTAWTR-LSQTTTPTA---TMSTATPSSTPETVHTSTVLTTTTTT 3869



 Score =  243 bits (620), Expect = 2e-63
 Identities = 269/954 (28%), Positives = 381/954 (39%), Gaps = 98/954 (10%)

Query: 1198 PPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPA 1257
            P  T    T    P T    T +     T+   G +++   +P + HT   PT T     
Sbjct: 4343 PTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFT 4402

Query: 1258 TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPAT 1317
               SS P  +   P   +T  TP  +      +++  T   PTV   TT  T +T S AT
Sbjct: 4403 VTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTT-TTVATGSMAT 4461

Query: 1318 TSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQP 1377
             S++  T+ TT T P P T+ T  T  +S +   P T  T  T        TT  T P  
Sbjct: 4462 PSSSTQTSGTTHTPPVPNTTAT--THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPST 4519

Query: 1378 GQPTRPTATETTQTRTTTEYTTPQ-TPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTP 1436
            G    P AT  T   +T   ++P  +  TT SPP+ G+  P  G  TATS    T  P+ 
Sbjct: 4520 GTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTP--GHTTATSRTTATATPSK 4577

Query: 1437 SHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSA-SNHSAPT-----GTIPPPTTL 1490
            +   T LP      S+    P T  V T    Q A S   ++S P      G     + +
Sbjct: 4578 TRTSTLLP------SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNI 4631

Query: 1491 KATGSTHTAPPITPTTSGTSQAHSS----------------------------------- 1515
            +A G      P+       +Q                                       
Sbjct: 4632 RAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEI 4691

Query: 1516 --FSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRP---P 1570
              F  N         TSST  P  TP  TT I    T+T T T    + +  SS P   P
Sbjct: 4692 RVFCCNYGHCPSTPATSSTAMPSSTP-GTTWILTELTTTATTTASTGSTATPSSTPGTAP 4750

Query: 1571 PPFTTHSPPT-----GSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVT 1625
            PP    SP T      S   SS+ P TAT+    T+  T S   +  P       T+   
Sbjct: 4751 PPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTL 4810

Query: 1626 PSTHTVITPTHAQMATSASIHSMPTGTI--PPPTTLKATGSTHTAPTMTLTTSGTSQALS 1683
            P   T    T + +  S++  +  T T+     TT +AT ST T      +T GT+  L+
Sbjct: 4811 PEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPS----STPGTTWILT 4866

Query: 1684 SLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTA 1743
             L TA T+T+    T++      T+   T +T   T+T +   T T S T  +    +  
Sbjct: 4867 ELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEP 4926

Query: 1744 KTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSP- 1802
             T+ ++   T ST     +ST  T+ TP H ST   TP   ++ AT S  P   T     
Sbjct: 4927 STTATVTVPTGST--ATASSTQATAGTP-HVSTTATTPTVTSSKATPSSSPGTATALPAL 4983

Query: 1803 -PTGTTP-ISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPST-HTVIIPT 1859
              T TTP  +S   + ++S  TT T  +     TT PT   S +T   TP T HT  + T
Sbjct: 4984 RSTATTPTATSFTAIPSSSLGTTWTRLS----QTTTPTATMSTATPSSTPETVHTSTVLT 5039

Query: 1860 HTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSF-STAKT-STS 1917
             T   T A      TG++  P++    G+ HT    T TT+G + +PSS   TA T  T+
Sbjct: 5040 ATATTTGA------TGSVATPSS--TPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTT 5091

Query: 1918 LPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSP 1977
             P  T ST H   TP  TT+ +   T+T T T   ++T+  SS L T        T ++ 
Sbjct: 5092 TPMSTMSTIHTSSTP-ETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATT 5150

Query: 1978 FSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHT-QMATSA 2036
             ++TG  TAT   T  T    + P T     VP  ST+    +  + + T HT ++ T+ 
Sbjct: 5151 TAATG-STATLSSTPGTTWILTEPSTIATVMVPTGSTA----TASSTLGTAHTPKVVTTM 5205

Query: 2037 SIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISS 2090
            +   T T +  P ++   T  T    P ++ T   S   SS  T    + F SS
Sbjct: 5206 ATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSS 5259



 Score =  242 bits (617), Expect = 4e-63
 Identities = 329/1262 (26%), Positives = 490/1262 (38%), Gaps = 168/1262 (13%)

Query: 1198 PPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPA 1257
            P  T    T    P T    T +   T T+   G +++   +P + HT   PT T     
Sbjct: 3841 PTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFT 3900

Query: 1258 TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPAT 1317
               SS P  +   P   +T  TP         +++  T    TV   TT  T +T S AT
Sbjct: 3901 ATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVL-TTTTTTVATGSMAT 3959

Query: 1318 TSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQP 1377
             S++  T+ TT T P P T+ T  T  +S     P T  T  T        TT  T P  
Sbjct: 3960 PSSSTQTSGTTHTPPVPNTTAT--THGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST 4017

Query: 1378 GQPTRPTATETTQTRTTTEYTTPQ-TPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTP 1436
                 P AT +T   +T   ++P  +  TT SPP+ G+  P  G    TS    T  P+ 
Sbjct: 4018 VTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTP--GHTRGTSRTTATATPSK 4075

Query: 1437 SHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSA-SNHSAPT-----GTIPPPTTL 1490
            +   T LP      S+    P T  V T    Q A S   ++S P      G     + +
Sbjct: 4076 TRTSTLLP------SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNI 4129

Query: 1491 KATGSTHTAPPITPTTSGTSQA----------------HSSFSTNKTPT---------SL 1525
            +A G      P+       +Q                       N+             +
Sbjct: 4130 RAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEI 4189

Query: 1526 HSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPF 1585
                 +  H   TP +++T TP+ T   T      T +AT++      +T S  T SS  
Sbjct: 4190 RVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTE-----STGSTATPSSTP 4244

Query: 1586 SSTGPMTATSFKTTTTYPTPS---HPQTTLPTHVPPFSTSLVTPS-THTVITPTHAQMAT 1641
             +T  +T  S   T T PT S      T      P  ST+  TP+ T +  TP  +    
Sbjct: 4245 GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTA 4304

Query: 1642 SASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSST 1701
            +A      T T P  T+  A       P+ +L T+ T  + ++  TA  ST+  S T  T
Sbjct: 4305 TALPALRSTATTPTATSFTA------IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET 4358

Query: 1702 HHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEV 1761
             H     T+T   T    S  TP  T  T+ T++  ++ +T  T T   S  ++   P  
Sbjct: 4359 AHTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVW 4418

Query: 1762 TSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQ 1821
             ST+TT  T   T T +  P    T+ T + L T  TT +  +  TP SST        Q
Sbjct: 4419 ISTTTTPTTSGSTVTPSSVP---GTTHTPTVLTTTTTTVATGSMATPSSST--------Q 4467

Query: 1822 TTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPT 1881
            T+ T  TP  P+TT  TH  S S S    S HTV         TSA+  ++ T  I  P 
Sbjct: 4468 TSGTTHTPPVPNTTATTHGRSLSPS----SPHTV-----RTAWTSATSGTLGTTHITEP- 4517

Query: 1882 TIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYH--TSSTHHPEVTPTSTTNIT 1939
               +TG++HT    T TT  ++ + SS   +  +T  P    T++  H   T  +T   T
Sbjct: 4518 ---STGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATAT 4574

Query: 1940 PKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPP--TGSSPFSSTGPMTATSFQTTTTY-- 1995
            P  T T T  P    +S +S+ + T  TT   P    S     + PM   S     TY  
Sbjct: 4575 PSKTRTSTLLP----SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSN 4630

Query: 1996 -----------PTPSHPQTTLPTHVPPFSTSLVTPST--HTVIITTHTQMAT-------S 2035
                       P     +      VP      V   +    ++     Q+          
Sbjct: 4631 IRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYE 4690

Query: 2036 ASIHSTPTGTVPPPTTLKATGSTHTAPPMT-----VTTSGTSQTHSSFSTATASSS---- 2086
              +     G  P      +T    + P  T     +TT+ T+ T S+ STAT SS+    
Sbjct: 4691 IRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATT-TASTGSTATPSSTPGTA 4749

Query: 2087 ----FISSSSWLPQNSSSRPPSSP---ITTQLPHLSS----------------------- 2116
                 ++S +  P  +SS+  SS      T LP L+S                       
Sbjct: 4750 PPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809

Query: 2117 ----ATTPVSTTNQLSSSFSPSPSAPSTV-SSYVPSSHSSPQTSSPSVGTSSSFVSAPV- 2170
                 TTPV+T + +  S +P  +  STV ++   ++ ++  TS+PS    ++++   + 
Sbjct: 4810 LPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELT 4869

Query: 2171 --HSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPI 2228
               +TT ++G  ++ S+ P T  +       ++  AST   AT   T  + + L+     
Sbjct: 4870 TAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTT 4929

Query: 2229 STVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSL 2288
            +TVTV PT S+  ASST A   TP  + +  T    SS++T S S    T +P     + 
Sbjct: 4930 ATVTV-PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTAT 4988

Query: 2289 T---SGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
            T   +  T IP+S +    TR    T +PT    T S     STP +   S++ T T T+
Sbjct: 4989 TPTATSFTAIPSSSLGTTWTR-LSQTTTPTA---TMSTATPSSTPETVHTSTVLTATATT 5044

Query: 2346 PG 2347
             G
Sbjct: 5045 TG 5046



 Score =  241 bits (615), Expect = 6e-63
 Identities = 312/1138 (27%), Positives = 463/1138 (40%), Gaps = 162/1138 (14%)

Query: 1253 PLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAST 1312
            P  PAT +++ P+++ G     TT +  + T+    TAT  STA  P+ T  T       
Sbjct: 3555 PSTPATSSTATPSSTPG-----TTWILTEQTTAATTTATTGSTAI-PSSTPGTAPPPKVL 3608

Query: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372
             S ATT TA S+  T+ + P  AT     TLP  T+     T  + T    P P+ T G 
Sbjct: 3609 TSTATTPTATSSKATSSSSPRTAT-----TLPVLTSTATKSTATSFT----PIPSFTLGT 3659

Query: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHT--------THSPPTAGSPVPSTGPVT- 1423
            T   P Q T P AT +T   ++T    P+T HT        T +  T+    PS+ P T 
Sbjct: 3660 TGTLPEQTTTPMATMSTIHPSST----PETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3715

Query: 1424 ---------ATSFHATTTYPTPS----------HPETTLPTHVPPFSTSL-----VTPST 1459
                     AT+  AT    TPS           P TT    VP  ST+       T  T
Sbjct: 3716 WILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGT 3775

Query: 1460 HTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTN 1519
              V+T T A   T  S+ + P+ +    T L A  ST T P  T  T+  S +  +  T 
Sbjct: 3776 LKVLTST-ATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTR 3834

Query: 1520 KTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPP 1579
             + T+  + T ST  P  TP +  T T   T+T T T    + +  SS P    TT  P 
Sbjct: 3835 LSQTTTPTATMSTATPSSTPETVHTSTV-LTTTTTTTRATGSVATPSSTPGTAHTTKVPT 3893

Query: 1580 TGSSPFSST---GPMTATS---FKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIT 1633
            T ++ F++T    P TA +   + +TTT PT +   T  P+ +P       T  T TV+T
Sbjct: 3894 TTTTGFTATPSSSPGTALTPPVWISTTTTPT-TRGSTVTPSSIPG------TTHTATVLT 3946

Query: 1634 PTHAQMATSASIHSMPTGTIPPPTTLKATGSTHT--APTMTLTTSGTSQALSSLNTAKTS 1691
             T   +AT     SM T    P ++ + +G+THT   P  T TT G S   SS +T +T 
Sbjct: 3947 TTTTTVATG----SMAT----PSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRT- 3997

Query: 1692 TSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHS 1751
                + TS+T    +    TT+IT   T T   P   TTS T  S  + S      S H 
Sbjct: 3998 ----AWTSAT----SGILGTTHITEPSTVTSHTP-AATTSTTQHSTPALS------SPHP 4042

Query: 1752 HTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISS 1811
             + +T  P    T+    TP HT   +RT    T S T +    P +  S P  T   + 
Sbjct: 4043 SSRTTESPPSPGTT----TPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTG 4098

Query: 1812 TGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHS 1871
              P  A S     +YP P        T+                        A   ++  
Sbjct: 4099 CEPQCAWSEWLDYSYPMPGPSGGDFDTY--------------------SNIRAAGGAVCE 4138

Query: 1872 MPTG-----TIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTH 1926
             P G        P   ++  G                +    F          +  +  H
Sbjct: 4139 QPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGH 4198

Query: 1927 HPEVTPTSTTN----------ITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSS 1976
             P    TS+T           I  K T+T T T    +T+  SS   T +    P T ++
Sbjct: 4199 CPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTAT 4258

Query: 1977 PFSSTGPMTATSFQTTTTYPTPSHPQT-TLPTHVPPFSTSLVTPSTHTVI--ITTHTQMA 2033
                TG  TAT+  T  T  TP    T T PT     +T   +P T T +  + +     
Sbjct: 4259 VTVPTG-STATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTP 4317

Query: 2034 TSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQT--HSSFSTATASSSFISSS 2091
            T+ S  + P+ ++    T  +  +T TA   T T S T +T   S+  T TA+++  + S
Sbjct: 4318 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGS 4377

Query: 2092 SWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVS-SYVPSSHS 2150
               P    S  P +  TT++P     TT    T   SSS   + + P  +S +  P++  
Sbjct: 4378 VATP----SSTPGTAHTTKVP----TTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSG 4429

Query: 2151 SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAAS--TTI 2208
            S  T S   GT+ +       +TT+++GS ++ S+   T+  + +P  P++ A +   ++
Sbjct: 4430 STVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSL 4489

Query: 2209 RATLPHTISSPFT--LSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSS 2266
              + PHT+ + +T   S  L  + +T   T +SH  ++T        T  + H+ PA SS
Sbjct: 4490 SPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT--------TGTTQHSTPALSS 4541

Query: 2267 QSTTSRSTSL--TTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHP-GPTLSPTTRFLTS 2321
               +SR+T    +    T G  + TS  T   T   T  +T  P  PT +P T  +T+
Sbjct: 4542 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 4599



 Score =  228 bits (582), Expect = 4e-59
 Identities = 335/1263 (26%), Positives = 493/1263 (39%), Gaps = 220/1263 (17%)

Query: 1201 TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLT 1260
            T  P  T    T  S P  V   T  +TT     +TG   + + TP +   T +   T T
Sbjct: 3838 TTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTT 3897

Query: 1261 SSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT---------VTQATTRATAS 1311
                T SS     P TA+TP        T T R +   P+             TT  T +
Sbjct: 3898 GFTATPSSS----PGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVA 3953

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGTS------PTLPKSTNQELPGTTA-----TQTT 1360
            T S AT S++  T+ TT T P P T+ T+      P+ P +        T+     T  T
Sbjct: 3954 TGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHIT 4013

Query: 1361 GPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTG 1420
             P    + T   TT      T   ++    +RTT    +P T    H+  T+ +   +T 
Sbjct: 4014 EPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATP 4073

Query: 1421 PVTATSFHATTTYPTPSHPETTLPTHV-PPFSTSLVTPSTHTVITPTHAQMATSASNHSA 1479
              T TS    ++ PT +   T + T   P  + S     ++ +  P+     T ++  +A
Sbjct: 4074 SKTRTSTLLPSS-PTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA 4132

Query: 1480 PTGTIPPPTTLKATGSTHTAPPITPTTSGT--SQAHSSFSTNKTPTS---------LHSH 1528
                   P  L+         P+         S        N+             +   
Sbjct: 4133 GGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVF 4192

Query: 1529 TSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSST 1588
              +  H   TP +++T TP+ T   T      T +AT        TT S  TGS      
Sbjct: 4193 CCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTAT--------TTES--TGS------ 4236

Query: 1589 GPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSM 1648
               TAT   T  T    + P TT    VP  ST+  + +  T  TP           H  
Sbjct: 4237 ---TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTP-----------HVS 4282

Query: 1649 PTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
             T T P  T+ KAT           ++ GT+ AL +L +  T                  
Sbjct: 4283 TTATTPTVTSSKAT---------PFSSPGTATALPALRSTAT------------------ 4315

Query: 1709 TSTTNITPNPTS-TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPE--VTSTS 1765
                  TP  TS T  P  ++ T+ T  S+++  TA  ST+  S T  T H    +T+T+
Sbjct: 4316 ------TPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTA 4369

Query: 1766 TTSITPNHTSTGTRTP-VAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATS---FQ 1821
            TT+      +T + TP  AHTT     ++PT  TT     G T   S+ P TA +   + 
Sbjct: 4370 TTTRATGSVATPSSTPGTAHTT-----KVPTTTTT-----GFTVTPSSSPGTARTPPVWI 4419

Query: 1822 TTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPT 1881
            +TTT PT S   T  P+ VP       T  T TV+  T T +AT     SM T    P +
Sbjct: 4420 STTTTPTTSGS-TVTPSSVPG------TTHTPTVLTTTTTTVATG----SMAT----PSS 4464

Query: 1882 TIKATGSTHT--APPMTPTTSGTSQSPSSFSTAKTS-TSLPYHTSSTHHPEVTPTSTTNI 1938
            + + +G+THT   P  T TT G S SPSS  T +T+ TS    T  T H     T T+  
Sbjct: 4465 STQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS-- 4522

Query: 1939 TPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST-GPMTATSFQTTTTYPT 1997
               HT   T     H+T A SS  P+  TT SPP   SP ++T G  TATS  T T  P+
Sbjct: 4523 ---HTPAATTGTTQHSTPALSSPHPSSRTTESPP---SPGTTTPGHTTATSRTTATATPS 4576

Query: 1998 PSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGS 2057
             +   T LP        S  T +  T ++T               TG  P     +    
Sbjct: 4577 KTRTSTLLP--------SSPTSAPITTVVT---------------TGCEPQCAWSEWLDY 4613

Query: 2058 THTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT--QLPHLS 2115
            ++   PM   + G   T+S+   A  +   +       +  +   P  P+    Q+   S
Sbjct: 4614 SY---PMPGPSGGDFDTYSNIRAAGGA---VCEQPLGLECRAQAQPGVPLGELGQVVECS 4667

Query: 2116 SATTPVSTTNQLSSSFSPSPSAPSTVS----SYVPSSHSSPQTSSPSVGTSSSFVSAPVH 2171
                 V    +    F    +    V      + PS+ ++  T+ PS    ++++   + 
Sbjct: 4668 LDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELT 4727

Query: 2172 STTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTV 2231
            +T  ++ S  S +T  +T   +  P   +SPA + T  ++   + SSP T +  LP+ T 
Sbjct: 4728 TTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRT-ATTLPVLTS 4786

Query: 2232 T--------VSPTPSSHLAS---------------STIAFPSTPRTTASTHTAPAFSSQS 2268
            T        V+P PSS L +               STI   STP T   THT+   ++++
Sbjct: 4787 TATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPET---THTSTVLTTKA 4843

Query: 2269 TTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVT-NLTTRHPGPTLSPTTRFLTSSLTAHG 2327
            TT+R+TS +T  P+S     T G T I T   T   TT   GPT +P++   T+ +    
Sbjct: 4844 TTTRATS-STSTPSS-----TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEL 4897

Query: 2328 STPASAPVSSLGTPTPTS-PGVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIIT 2386
            +T A+   S+  T TP+S PG   +      +T     A VTV     A  S+      T
Sbjct: 4898 TTTATTTASTGSTATPSSTPGTTWI------LTEPSTTATVTVPTGSTATASSTQATAGT 4951

Query: 2387 QQV 2389
              V
Sbjct: 4952 PHV 4954



 Score =  226 bits (576), Expect = 2e-58
 Identities = 312/1119 (27%), Positives = 450/1119 (40%), Gaps = 145/1119 (12%)

Query: 1333 TPATSGTSPTLPKSTNQELPGTT--ATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQ 1390
            TPATS T+  +P ST    PGTT   T+ T    T  ST    TP     T    TE + 
Sbjct: 3055 TPATSSTA--MPSST----PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPST 3108

Query: 1391 TRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTP-SHPETTLPTHVPP 1449
            T T T   T  T   + +  TAG+P  ST   TAT+   T++  TP S P T   T +P 
Sbjct: 3109 TATVT-VPTGSTATASSTQATAGTPHVST---TATTPTVTSSKATPFSSPGTA--TALPA 3162

Query: 1450 FSTSLVTPSTHTVITPTHAQMATS---ASNHSAPTGTIPPPTTLKATGSTHTAPPITPTT 1506
              ++  TP+  +      + + T+    S  + PT T+   T      + HT+  +T T 
Sbjct: 3163 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTA 3222

Query: 1507 SGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTST------------RT 1554
            + T    S  + + TP + H+        +V  T+TT  T  P+S+             T
Sbjct: 3223 TTTGATGSVATPSSTPGTAHT-------TKVLTTTTTGFTATPSSSPGTARTLPVWISTT 3275

Query: 1555 RTPVAHTNSATSSRPPPPFTTHSPP--TGSSPFSSTGPMTATSFKTTT--TYPTPSHPQT 1610
             TP    ++ T S  P   TTH+P   T ++   +TG M   S  T T  T  TP  P T
Sbjct: 3276 TTPTTRGSTVTPSSIPG--TTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNT 3333

Query: 1611 TLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670
            T  TH      SL   S HTV T       TSA+  ++ T  I  P+T    G++HT   
Sbjct: 3334 TATTH----GRSLSPSSPHTVRTAW-----TSATSGTLGTTHITEPST----GTSHTPAA 3380

Query: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730
             T TT  ++ ALSS + +  +T       +T      +TS T      T+T TP  T T+
Sbjct: 3381 TTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRT------TATATPSKTRTS 3434

Query: 1731 SGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATS 1790
              T    S  S   T+             E    S     P+     T + +     A  
Sbjct: 3435 --TLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVC 3492

Query: 1791 SRLPTPFTTHSPPTGTTPISSTGPVTATS---------------FQTTTTYPT------- 1828
             + P      +      P+   G V   S               F+    Y         
Sbjct: 3493 EQ-PLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNY 3551

Query: 1829 ---PSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKA 1885
               PS P T+  T  PS +       T      T T    S +I S   GT PPP  + +
Sbjct: 3552 GHCPSTPATS-STATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTS 3610

Query: 1886 TGSTHTAP---------PMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHH--PEVTPT- 1933
            T +T TA          P T TT     S ++ STA + T +P  T  T    PE T T 
Sbjct: 3611 TATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTP 3670

Query: 1934 --STTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT 1991
              + + I P  T   T T    TT A+++R  +  +T S   G++   +     AT+   
Sbjct: 3671 MATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAA 3730

Query: 1992 TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTT 2051
            T    TPS    T      P +T+ VT  T +         AT++S  +T         T
Sbjct: 3731 TGPTATPSSTPGTTWILTEPSTTATVTVPTGST--------ATASSTRAT-------AGT 3775

Query: 2052 LKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQL 2111
            LK   ST T P  TV +S  + + SS  TATA  +  S+++     S +  PSS + T  
Sbjct: 3776 LKVLTSTATTP--TVISSRATPS-SSPGTATALPALRSTATTPTATSVTAIPSSSLGTAW 3832

Query: 2112 PHLSSATTPVSTTNQLSSSFSPSPSAPSTV---SSYVPSSHSSPQTSSPSVGTSSSFVSA 2168
              LS  TTP +T +  + S +P     STV   ++    +  S  T S + GT+ +    
Sbjct: 3833 TRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHT-TKV 3891

Query: 2169 PVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATL-PHTISSPFTLSALLP 2227
            P   TT ++G  ++ S+ P TA     P++ S+    TT  +T+ P +I      + +L 
Sbjct: 3892 P---TTTTTGFTATPSSSPGTA--LTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLT 3946

Query: 2228 ISTVTVS----PTPSSHL-ASSTIAFPSTPRTTASTH--TAPAFSSQSTTSRSTSLTTRV 2280
             +T TV+     TPSS    S T   P  P TTA+TH  + P  S  +  +  TS T+ +
Sbjct: 3947 TTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGI 4006

Query: 2281 PTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLS---PTTRFLTSSLTAHGSTPASAPVSS 2337
              +  ++  S VT   T   T  TT+H  P LS   P++R   S  +   +TP     +S
Sbjct: 4007 LGTTHITEPSTVTS-HTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTS 4065

Query: 2338 LGTPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGAC 2376
              T T T P                 +  V  T CE  C
Sbjct: 4066 RTTATAT-PSKTRTSTLLPSSPTSAPITTVVTTGCEPQC 4103



 Score =  221 bits (564), Expect = 5e-57
 Identities = 337/1270 (26%), Positives = 484/1270 (38%), Gaps = 226/1270 (17%)

Query: 1194 VPC----MPPTTPQPP----TTPQLPT----TGSRPTQVWPMTGTSTTIGLLSSTGPSPS 1241
            VPC     P T+PQP     T P +PT    T +  T +W      +T  L S TG S  
Sbjct: 2123 VPCGPSPAPGTSPQPSLSASTEPAVPTPTQTTATEKTTLWVTPSIRSTAALTSQTGSSSG 2182

Query: 1242 S-NHTPASPTQTPLLPATLTSS--------------------KPTASSGEPPRPTTAVTP 1280
                TP++P  T   P    +                     K  A+ G   +    +  
Sbjct: 2183 PVTVTPSAPGTTTCQPRCQWTEWFDEDYPKSEQLGGDVESYDKIRAAGGHLCQQPKDIEC 2242

Query: 1281 QATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTS 1340
            QA S   P  TL     K            +           +     +        G +
Sbjct: 2243 QAESF--PNWTLAQVGQKVHCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRA 2300

Query: 1341 PTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTR-PTATETTQTRTTTEYTT 1399
             T P +T  E   TT TQ     P P S+ G T   P   T  PT +E     T+  YT+
Sbjct: 2301 TTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGL---TSPRYTS 2357

Query: 1400 PQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTH--VPPFSTSLVT- 1456
                 TT  P T       T P  ATS               TLPT   +P  + SL T 
Sbjct: 2358 TLGTATTGGPTTPAGSTEPTVPGVATS---------------TLPTRSALPGTTGSLGTW 2402

Query: 1457 -PSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSS 1515
             PS    + PT     T A++ + PTGT    T  K   +T  AP +T   S TSQA +S
Sbjct: 2403 RPSQPPTLAPT-----TMATSRARPTGTAS--TASKEPLTTSLAPTLTSELS-TSQAETS 2454

Query: 1516 FSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTT 1575
                            T   E T +  T  T +  +TR +     T       P      
Sbjct: 2455 ----------------TPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAG 2498

Query: 1576 HSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST------- 1628
                T  +  ++ G M       +      ++P+ ++       + SL T  T       
Sbjct: 2499 GDMETFENIRAAGGKMCWAP--KSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQT 2556

Query: 1629 --------------------HTVITPTHAQMATSAS------IHSMPTGTIPPPTTLKAT 1662
                                H   TP  +  AT +S      I + PT T    TT  +T
Sbjct: 2557 GRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTA---TTTAST 2613

Query: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTG 1722
            GST T PT TL T+   + L++  T  T TS  +  SS+        +  +    PT+T 
Sbjct: 2614 GSTAT-PTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS 2672

Query: 1723 TPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPV 1782
              P+  ++ GT+ +R S +T  T+T   +  SST  PE   TST  +T   T+TG    V
Sbjct: 2673 VTPIPSSSLGTTWTRLSQTTTPTATMSTATPSST--PETAHTSTV-LTATATTTGATGSV 2729

Query: 1783 AHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATS---FQTTTTYPTPSHPHTTLPTH 1839
            A T S+T     T     +  TG T   S+ P TA +   + +TTT PT +   T  P+ 
Sbjct: 2730 A-TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPT-TRGSTVTPSS 2787

Query: 1840 VPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAP-PMT-P 1897
            +P       T  T TV+  T T +AT     SM T    P ++ + +G+THT P P T  
Sbjct: 2788 IPG------TTHTATVLTTTTTTVATG----SMAT----PSSSTQTSGTTHTPPVPNTMA 2833

Query: 1898 TTSGTSQSPSSFSTAKTS-TSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTS 1956
            TT G S  PSS  T +T+ TS       T H  +T  ST      HT   T     H+T 
Sbjct: 2834 TTHGRSLPPSSPHTVRTAWTSATSGILGTTH--ITEPSTVT---SHTLAATTGTTQHSTP 2888

Query: 1957 ASSSRLPTPFTTHSPPTGSSPFSST-GPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTS 2015
            A SS  P+  TT SPP   SP ++T G  TATS  T T  P+ +   T LP      S+ 
Sbjct: 2889 ALSSPHPSSRTTESPP---SPGTTTPGHTTATSRTTATATPSKTRTSTLLP------SSP 2939

Query: 2016 LVTPSTHTVIITTHTQMATSASI-HSTPT-----GTVPPPTTLKATGSTHTAPPMTVTTS 2069
               P T  V +    Q A S  + +S P      G     + ++A G      P+ +   
Sbjct: 2940 TSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECR 2999

Query: 2070 GTSQTHS--------------------------------SFSTATASSSFISSSSWLPQN 2097
              +Q                                   ++       ++    S    +
Sbjct: 3000 AQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS 3059

Query: 2098 SSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSP 2157
            S++ P S+P TT +  L+  TT  +TT    S+ +PS +  +T     PS+ ++    + 
Sbjct: 3060 STAMPSSTPGTTWI--LTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG 3117

Query: 2158 SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTIS 2217
            S  T+SS         T  +   S+ +T PT  S  A+P   SSP  +T + A L  T +
Sbjct: 3118 STATASST------QATAGTPHVSTTATTPTVTSSKATPF--SSPGTATALPA-LRSTAT 3168

Query: 2218 SPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLT 2277
            +P         +  + +  PSS L ++      T   TA+  TA   S+  T   ST LT
Sbjct: 3169 TP---------TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 3219

Query: 2278 TRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSS 2337
            T        + T+G TG   +P +   T H    L+ TT   T++ ++   T  + PV  
Sbjct: 3220 T-------TATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWI 3272

Query: 2338 LGTPTPTSPG 2347
              T TPT+ G
Sbjct: 3273 STTTTPTTRG 3282



 Score =  221 bits (564), Expect = 5e-57
 Identities = 307/1089 (28%), Positives = 447/1089 (41%), Gaps = 180/1089 (16%)

Query: 1352 PGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPT 1411
            P T AT +T    TP+ST G T            TE T   TTT  TT  T   + +P T
Sbjct: 3555 PSTPATSSTA---TPSSTPGTTW---------ILTEQTTAATTTA-TTGSTAIPSSTPGT 3601

Query: 1412 AGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMA 1471
            A  P P     TAT+  AT++  T S    T  T   P  TS  T ST T  TP      
Sbjct: 3602 A--PPPKVLTSTATTPTATSSKATSSSSPRTATT--LPVLTSTATKSTATSFTPI----- 3652

Query: 1472 TSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSS 1531
               S     TGT+P  TT      +   P  TP T+ TS   ++ +T    TS  S  SS
Sbjct: 3653 --PSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSS 3710

Query: 1532 THH-----PEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFS 1586
            T        E+T  +TTT    PT+T + TP     +      P    T + PTGS+  +
Sbjct: 3711 TPGTTWILTELTTAATTTAATGPTATPSSTP----GTTWILTEPSTTATVTVPTGSTATA 3766

Query: 1587 STGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIH 1646
            S+   TA + K  T+         T PT +   +T   +P T T +    +         
Sbjct: 3767 SSTRATAGTLKVLTS-------TATTPTVISSRATPSSSPGTATALPALRS--------- 3810

Query: 1647 SMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEA 1706
               T T P  T++ A       P+ +L T+ T  + ++  TA  ST+  S T  T H   
Sbjct: 3811 ---TATTPTATSVTA------IPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTST 3861

Query: 1707 TSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTST 1766
              T+TT  T    S  TP  T  T+ T++  ++ +T  T+T   S  ++   P   ST+T
Sbjct: 3862 VLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTT 3921

Query: 1767 TSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTY 1826
            T  T   T T +  P    T+ T++ L T  TT +  +  TP SST        QT+ T 
Sbjct: 3922 TPTTRGSTVTPSSIP---GTTHTATVLTTTTTTVATGSMATPSSST--------QTSGTT 3970

Query: 1827 PTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKAT 1886
             TP  P+TT  TH      SL   S HTV         TSA+   + T  I  P+T+   
Sbjct: 3971 HTPPVPNTTATTH----GRSLPPSSPHTV-----RTAWTSATSGILGTTHITEPSTV--- 4018

Query: 1887 GSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYH--TSSTHHPEVTPTSTTNITPKHTS 1944
             ++HT    T TT  ++ + SS   +  +T  P    T++  H   T  +T   TP  T 
Sbjct: 4019 -TSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 4077

Query: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSPP--TGSSPFSSTGPMTATSFQTTTTYPT----- 1997
            T T  P    +S +S+ + T  TT   P    S     + PM   S     TY       
Sbjct: 4078 TSTLLP----SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAG 4133

Query: 1998 -----------------PSHPQTTLPTHVP-PFSTSLVTPSTH-------------TVII 2026
                             P  P   L   V       LV  +                V  
Sbjct: 4134 GAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 4193

Query: 2027 TTHTQMATSASIHSTPTGTVPPPTT------------LKATGSTHT-----------APP 2063
              +    ++ +  ST T +  P TT             ++TGST T             P
Sbjct: 4194 CNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEP 4253

Query: 2064 MTVTT----SGTSQTHSSFSTATASSSFISSSSWLPQNSSSR--PPSSPIT-TQLPHL-S 2115
             T  T    +G++ T SS + ATA +  +S+++  P  +SS+  P SSP T T LP L S
Sbjct: 4254 STTATVTVPTGSTATASS-TQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRS 4312

Query: 2116 SATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTS-SSFVSAPVHSTT 2174
            +ATTP +T+     S S   +      +  P++  S  T S +  T+ +S V     +TT
Sbjct: 4313 TATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTT 4372

Query: 2175 LSSGSHSSLSTHPTTASVSASPL-----FPSSPAASTTIRATLPHTISSPFTL----SAL 2225
             ++GS ++ S+ P TA  +  P      F  +P++S     T P  IS+  T     S +
Sbjct: 4373 RATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTV 4432

Query: 2226 LPIS------TVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTR 2279
             P S      T TV  T ++ +A+ ++A PS+   T+ T   P   + + T+   SL+  
Sbjct: 4433 TPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPS 4492

Query: 2280 VPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAP-VSSL 2338
             P +   + TS  +G  T   T++T    G + +P     T+  T H +   S+P  SS 
Sbjct: 4493 SPHTVRTAWTSATSG--TLGTTHITEPSTGTSHTPAA---TTGTTQHSTPALSSPHPSSR 4547

Query: 2339 GTPTPTSPG 2347
             T +P SPG
Sbjct: 4548 TTESPPSPG 4556



 Score =  219 bits (559), Expect = 2e-56
 Identities = 340/1309 (25%), Positives = 502/1309 (38%), Gaps = 245/1309 (18%)

Query: 1146 QYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCYN------CSQDEYFDHEEGVCVPCMPP 1199
            Q  Q+ +C  H+   +C +  Q       + CYN      C  D++          C   
Sbjct: 2254 QVGQKVHCDVHFG-LVCRNWEQE---GVFKMCYNYRIRVLCCSDDH----------CRGR 2299

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHT---PASPTQTPLLP 1256
             T  PPTT     T            T+TT  L S+  P+ S   T   PAS T  P L 
Sbjct: 2300 ATTPPPTTELETAT------------TTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLS 2347

Query: 1257 ATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPA 1316
              LTS + T++ G            AT+G P T    +  T P V  AT+     +A P 
Sbjct: 2348 EGLTSPRYTSTLGT-----------ATTGGPTTPAGSTEPTVPGV--ATSTLPTRSALPG 2394

Query: 1317 TTS---TAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPT 1373
            TT    T + +   T+   T ATS   PT   ST  + P TT+   T       S    +
Sbjct: 2395 TTGSLGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETS 2454

Query: 1374 TPQPGQPTRPTATETTQTRTT--------TEYTTPQTPHTTHSPPTAGSPVPSTGPVTAT 1425
            TP+      P    TT   TT        TE+     P    +   AG  + +   + A 
Sbjct: 2455 TPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFP----TSGVAGGDMETFENIRAA 2510

Query: 1426 S-----FHATTTYPTPSHPETTLPTHVPPFSTSLVTPST--------------------- 1459
                     +      ++PE ++       + SL T  T                     
Sbjct: 2511 GGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVL 2570

Query: 1460 ------HTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGST----------HTAPP-- 1501
                  H   TP  +  AT +S          P TT   T ST           TAPP  
Sbjct: 2571 CCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPK 2630

Query: 1502 ITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS---------T 1552
            +  TT+ T    SS +T  +     +   +      TPT+ T++TP P+S         +
Sbjct: 2631 VLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTA-TSVTPIPSSSLGTTWTRLS 2689

Query: 1553 RTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTT- 1611
            +T TP A  ++AT S  P   T H+    S+  ++T   T  +    T   TP    TT 
Sbjct: 2690 QTTTPTATMSTATPSSTPE--TAHT----STVLTATATTTGATGSVATPSSTPGTAHTTK 2743

Query: 1612 LPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTM 1671
            +PT      T+  + S  T +TP         S  + PT      T     G+THTA  +
Sbjct: 2744 VPTTTTTGFTATPSSSPGTALTP-----PVWISTTTTPTTRGSTVTPSSIPGTTHTATVL 2798

Query: 1672 TLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTS 1731
            T TT  T+ A  S+ T  +S               T TS T  TP       P    TT 
Sbjct: 2799 TTTT--TTVATGSMATPSSS---------------TQTSGTTHTP-----PVPNTMATTH 2836

Query: 1732 GTSQSRSSFSTAKTS-TSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATS 1790
            G S   SS  T +T+ TS  S    T H  +T  ST +   +HT   T     H+T A S
Sbjct: 2837 GRSLPPSSPHTVRTAWTSATSGILGTTH--ITEPSTVT---SHTLAATTGTTQHSTPALS 2891

Query: 1791 SRLPTPFTTHSPPT-GTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVT 1849
            S  P+  TT SPP+ GTT   + G  TATS  T T  P+ +   T LP      S+    
Sbjct: 2892 SPHPSSRTTESPPSPGTT---TPGHTTATSRTTATATPSKTRTSTLLP------SSPTSA 2942

Query: 1850 PSTHTVIIPTHTQMATSASI---HSMP---TGTIPPPTTIKATGSTHTAPPMTPTTSGTS 1903
            P T  V +    Q A S  +   + MP    G     + I+A G      P+       +
Sbjct: 2943 PITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQA 3002

Query: 1904 QS--PSSFSTAKTSTSLPY-----------------------------------HTSSTH 1926
            Q   P          SL +                                    TSST 
Sbjct: 3003 QPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTA 3062

Query: 1927 HPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTA 1986
             P  TP  TT I  + T+T T T    +T+  SS   T +    P T ++    TG  TA
Sbjct: 3063 MPSSTP-GTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTG-STA 3120

Query: 1987 TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTV 2046
            T+  T  T  TP H  TT  T  P  ++S  TP +     T    + ++A+  +  + T 
Sbjct: 3121 TASSTQATAGTP-HVSTTATT--PTVTSSKATPFSSPGTATALPALRSTATTPTATSFTA 3177

Query: 2047 PPPTTLKATG---STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPP 2103
             P ++L  T    S  T P  T++T+  S T  +  T+T  ++  +++      S + P 
Sbjct: 3178 IPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTG--ATGSVATPS 3235

Query: 2104 SSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYV-----PSSHSSPQTSSPS 2158
            S+P T    H +   T  +TT   +++ S SP    T+  ++     P++  S  T S  
Sbjct: 3236 STPGTA---HTTKVLT--TTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSI 3290

Query: 2159 VGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAAS--TTIRATLPHTI 2216
             GT+ +       +TT+++GS ++ S+   T+  + +P  P++ A +   ++  + PHT+
Sbjct: 3291 PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTV 3350

Query: 2217 SSPFT--LSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRST 2274
             + +T   S  L  + +T   T +SH  ++T        T  + H+ PA SS   +SR+T
Sbjct: 3351 RTAWTSATSGTLGTTHITEPSTGTSHTPAAT--------TGTTQHSTPALSSPHPSSRTT 3402

Query: 2275 SL--TTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHP-GPTLSPTTRFLT 2320
                +    T G    TS  T   T   T  +T  P  PT +P T  +T
Sbjct: 3403 ESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVT 3451



 Score =  165 bits (418), Expect = 4e-40
 Identities = 139/512 (27%), Positives = 203/512 (39%), Gaps = 79/512 (15%)

Query: 302  CPANQVYQEC--------GSACVKTCSNPQHSC-SSSCTFGCFCPEGTVLNDLSNNHTCV 352
            C A  VY +C        G+ C+++C      C S+ C  GC CP G V +       C+
Sbjct: 1453 CAAPMVYLDCSNSSAGTPGAECLRSCHTLDVGCFSTHCVSGCVCPPGLVSDGSGG---CI 1509

Query: 353  PVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARP 412
                CPCV + A Y PGE     C TC C   RW C+ R C G C   G     TFD   
Sbjct: 1510 AEEDCPCVHNEATYKPGETIRVDCNTCTCRNRRWECSHRLCLGTCVAYGDGHFITFDGDR 1569

Query: 413  YRFHGTCTYILLQS--PQLPEDGALMAVYDKSGVSHSETSLVAVVYLS------------ 458
            Y F G+C YIL Q         G    V +      + T+    + L             
Sbjct: 1570 YSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCSKAIKLFVEVRTAPAVSTP 1629

Query: 459  ----------------RQDKIVISQDEVVTNNGEAKWL--------PYKTRNITVFRQTS 494
                            RQ    +   E++   G  K +        PYK R + +F    
Sbjct: 1630 DPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARGPGGDPPYKIRYMGIFLVIE 1689

Query: 495  THLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGT 554
            TH  MA S+  +  V        ++ +   ++G+  GLCGNF+ +  +DF T      G 
Sbjct: 1690 TH-GMAVSWDRKTSV--------FIRLHQDYKGRVCGLCGNFDDNAINDFATRSRSVVGD 1740

Query: 555  ASLFVDSWR-AGNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAP 613
            A  F +SW+ + +CP AL  + DPC+ +   K  A+  CS+L   G  F  C + V+   
Sbjct: 1741 ALEFGNSWKLSPSCPDALAPK-DPCTANPFRKSWAQKQCSIL--HGPTFAACRSQVDSTK 1797

Query: 614  FYKRCVYQACNYEE--TFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCT-----G 666
            +Y+ CV  AC  +        C A+  Y  AC   G+ +  WR+  D C + C      G
Sbjct: 1798 YYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTP-DTCPLFCDFYNPHG 1855

Query: 667  NTTFSYNSQACERTCL-SLSDRATECHHSAVPVDGC--NCPDGTYLNQKGECVRKAQCPC 723
               + Y  Q C   CL +  + +  C      ++GC   CP       + +    AQC C
Sbjct: 1856 GCEWHY--QPCGAPCLKTCRNPSGHCLVDLPGLEGCYPKCPPSQPFFNEDQMKCVAQCGC 1913

Query: 724  ILE--GYKFILAEQSTVINGITCHCINGRLSC 753
              +   Y  + A   T  N  +C+C    + C
Sbjct: 1914 YDKDGNYYDVGARVPTAENCQSCNCTPSGIQC 1945



 Score =  151 bits (382), Expect = 7e-36
 Identities = 93/279 (33%), Positives = 138/279 (49%), Gaps = 22/279 (7%)

Query: 785  CAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQ--CVPPEECPCEFSGVSYPGGAEL 842
            CA TC       AC    C  GC C EG   +  GQ  CVP  +C C ++G +Y  GA  
Sbjct: 351  CADTCSNQEHSRAC-EDHCVAGCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAYAPGATY 409

Query: 843  HTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVN 902
             TDC  C+CS GRW+CQ+   CP TC++ G  H  TFDG+++   G+C Y+L T  C   
Sbjct: 410  STDCTNCTCSGGRWSCQE-VPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVL-TKPC--- 464

Query: 903  DSQPTFKILTENVICG-NSGVTCSRAIKIFL-GGLSVVLADRNYTVTGEEPHVQLGVT-- 958
                 F +L E   CG     TC +++ + L G  +VV+   +  V   + + QL ++  
Sbjct: 465  -DSSAFTVLAELRRCGLTDSETCLKSVTLSLDGAQTVVVIKASGEVFLNQIYTQLPISAA 523

Query: 959  ------PGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDD 1012
                  P    ++   S+  + NL L+    M + +++A   +   CGLCGNFN    DD
Sbjct: 524  NVTIFRPSTFFIIAQTSLGLQLNLQLV--PTMQLFMQLAPKLRGQTCGLCGNFNSIQADD 581

Query: 1013 FETRSRYVASSELELVNSWKESPLCGDV-SFVTDPCSLN 1050
            F T S  V ++     N++K    C ++ +   DPCSL+
Sbjct: 582  FRTLSGVVEATAAAFFNTFKTQAACPNIRNSFEDPCSLS 620



 Score =  144 bits (364), Expect = 8e-34
 Identities = 117/375 (31%), Positives = 162/375 (43%), Gaps = 31/375 (8%)

Query: 37   QTAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISR 96
            Q  P  G CS  G  H ST+D  +YD  G C+Y+ +  C D+  T   +LR+        
Sbjct: 1076 QDLPCPGTCSVQGGAHISTYDEKLYDLHGDCSYVLSKKCADSSFTVLAELRKCGLTDNEN 1135

Query: 97   IIVELGASVVTVSEAIISVKDIGV-ISLPYTS---NGLQITPFGQSVRLVAKQ--LELEL 150
             +  +  S+     AI    D GV ++  YT    +   IT F  S   +  Q  L L+L
Sbjct: 1136 CLKAVTLSLDGGDTAIRVQADGGVFLNSIYTQLPLSAANITLFTPSSFFIVVQTGLGLQL 1195

Query: 151  EVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG 210
             V   P   + V ++  + GQMCGLCGNF+    ++F +  G  +     AA        
Sbjct: 1196 LVQLVPLMQVFVRLDPAHQGQMCGLCGNFNQNQADDFTALSG--VVEATGAAFANTWKAQ 1253

Query: 211  EIC-----TFQDIPSTHVRQAQHARICTQLLTLVAPECS-----VSKEPFVLSCQADVAA 260
              C     +F+D  S  V    +AR     LT      S     ++ +PF  +C  D   
Sbjct: 1254 AACANARNSFEDPCSLSVENENYARHWCSRLTDPNSAFSRCHSIINPKPFHSNCMFDTCN 1313

Query: 261  APQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCS--VGQCPANQVYQECGSACVKT 318
              +   ++  CA LS Y   C+  G  +  WR  G+C+  +  CP +Q Y     AC  T
Sbjct: 1314 CER--SEDCLCAALSSYVHACAAKGVQLSDWRD-GVCTKYMQNCPKSQRYAYVVDACQPT 1370

Query: 319  C---SNPQHSCSSSC--TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI 373
            C   S    +CS S     GC CP GT LND      CVP  +CPC  HG + APGEV  
Sbjct: 1371 CRGLSEADVTCSVSFVPVDGCTCPAGTFLNDAG---ACVPAQECPCYAHGTVLAPGEVVH 1427

Query: 374  AACQTCRCTLGRWVC 388
                 C CT G+  C
Sbjct: 1428 DEGAVCSCTGGKLSC 1442



 Score =  144 bits (362), Expect = 1e-33
 Identities = 168/560 (30%), Positives = 242/560 (43%), Gaps = 67/560 (11%)

Query: 1201 TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPS--PSSNHT-PASPTQTPLLPA 1257
            TP P +T  L TTG+ P Q      T+T +  +S+  PS  P + HT     T+     A
Sbjct: 4797 TPIPSST--LGTTGTLPEQ------TTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRA 4848

Query: 1258 TLTSSKPTASSGEP---PRPTTAVTPQATSGLPPTATLRST-ATKPTVTQATTRATASTA 1313
            T ++S P+++ G        TTA T  A +G  PTAT  ST  T   +T+ TT AT +TA
Sbjct: 4849 TSSTSTPSSTPGTTWILTELTTAATTTAATG--PTATPSSTPGTTWILTELTTTAT-TTA 4905

Query: 1314 SPATTSTAQSTTRTTMTLPTPATSG-----TSPTLPKSTNQELPGTTATQTTGPRPTPAS 1368
            S  +T+T  ST  TT  L  P+T+      T  T   S+ Q   GT    TT   PT  S
Sbjct: 4906 STGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTS 4965

Query: 1369 TTGPTTPQPGQPTR-PTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSF 1427
            +    +  PG  T  P    T  T T T +T         + P++      T     T+ 
Sbjct: 4966 SKATPSSSPGTATALPALRSTATTPTATSFT---------AIPSSSLGTTWTRLSQTTTP 5016

Query: 1428 HATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPP 1487
             AT +  TPS    T+ T     +T+  T +T +V TP       S++  +A T  +P  
Sbjct: 5017 TATMSTATPSSTPETVHTSTVLTATATTTGATGSVATP-------SSTPGTAHTTKVPTT 5069

Query: 1488 TT--LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTI 1545
            TT    AT S+     +TP T+      S+  T+ TP + H+ T  T    +T  + +T 
Sbjct: 5070 TTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTA 5129

Query: 1546 TPNPTSTRTR-----TPVAHTNSAT------SSRPPPPFTTHSPPTGSSPFSSTGPMTAT 1594
            TP+ T   TR     T  A T +AT      SS P   +    P T ++    TG  TAT
Sbjct: 5130 TPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTG-STAT 5188

Query: 1595 SFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTV-ITPTHAQMATSASIHSMPTGTI 1653
            +  T  T  TP    TT+ T   P +T+   PS+ TV  T T A + +S    S+ T + 
Sbjct: 5189 ASSTLGTAHTPK-VVTTMAT--MPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSS 5245

Query: 1654 PPPTTLKATG--STHTAPTMTLTTSGTSQALSSLNTAKTS-TSLHSHTSSTHHAE----- 1705
               TTL+ TG  S+H +        G   +   +   KT     H +     H +     
Sbjct: 5246 SVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQ 5305

Query: 1706 -ATSTSTTNITPNPTSTGTP 1724
             A  TS   ++  P S+ +P
Sbjct: 5306 GACPTSPPPVSSAPLSSPSP 5325



 Score =  122 bits (307), Expect = 3e-27
 Identities = 176/725 (24%), Positives = 280/725 (38%), Gaps = 91/725 (12%)

Query: 1646 HSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAE 1705
            H     T PPPTT   T +T T   +  T   TS    +     ++T++ + +       
Sbjct: 2295 HCRGRATTPPPTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPR 2354

Query: 1706 ATSTSTTNITPNPTS-TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTST 1764
             TST  T  T  PT+  G+   TV    TS       T  T ++L   T S        T
Sbjct: 2355 YTSTLGTATTGGPTTPAGSTEPTVPGVATS-------TLPTRSALPGTTGSL------GT 2401

Query: 1765 STTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTT 1824
               S  P    T   T  A  T   S+    P TT   PT T+ +S++   T+T    TT
Sbjct: 2402 WRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETT 2461

Query: 1825 TYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHT----QMATSASIHSMPTGTIPPP 1880
              P  +   TT                   V  PT       M T  +I +        P
Sbjct: 2462 MSPLTN---TTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAP 2518

Query: 1881 TTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLP-YHTSSTHHPEVTPTSTTNIT 1939
             +I+     +    +       + S  +  T K       ++    ++  V      +  
Sbjct: 2519 KSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQTGRFNMCFNYNVRVLCCDDYSHC 2578

Query: 1940 PKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPS 1999
            P        TP   +T+  SS   T +    P T ++  +STG  TAT   T  T P P 
Sbjct: 2579 PS-------TPATSSTATPSSTPGTTWILTKPTTTATTTASTGS-TATPTSTLRTAPPPK 2630

Query: 2000 HPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTH 2059
               TT  T  P  ++S  TPS+      T T +    S  +TPT T   P    + G+T 
Sbjct: 2631 VLTTTATT--PTVTSSKATPSSSP---GTATALPALRSTATTPTATSVTPIPSSSLGTTW 2685

Query: 2060 TAPPMTVTTSGTSQTHSSFSTA-TASSSFI---SSSSWLPQNSSSRPPSSPITTQLPHLS 2115
            T    T T + T  T +  ST  TA +S +   ++++     S + P S+P T       
Sbjct: 2686 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAH----- 2740

Query: 2116 SATTPVSTTNQLSSSFSPSPSAPSTVSSYV-----PSSHSSPQTSSPSVGTSSSFVSAPV 2170
            +   P +TT   +++ S SP    T   ++     P++  S  T S   GT+ +      
Sbjct: 2741 TTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTT 2800

Query: 2171 HSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAAS--TTIRATLPHTISSPFT--LSALL 2226
             +TT+++GS ++ S+   T+  + +P  P++ A +   ++  + PHT+ + +T   S +L
Sbjct: 2801 TTTTVATGSMATPSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGIL 2860

Query: 2227 PISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFV 2286
              + +T   T +SH  ++T        T  + H+ PA SS   +SR+T            
Sbjct: 2861 GTTHITEPSTVTSHTLAAT--------TGTTQHSTPALSSPHPSSRTTES---------- 2902

Query: 2287 SLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSP 2346
                     P SP T      PG T +       +S T   +TP+    S+L   +PTS 
Sbjct: 2903 ---------PPSPGTTT----PGHTTA-------TSRTTATATPSKTRTSTLLPSSPTSA 2942

Query: 2347 GVCSV 2351
             + +V
Sbjct: 2943 PITTV 2947



 Score =  121 bits (304), Expect = 7e-27
 Identities = 184/744 (24%), Positives = 257/744 (34%), Gaps = 109/744 (14%)

Query: 35   SPQTAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRR----GP 90
            S Q  P  G CS  G  HFSTFD   Y   G C+Y+    C  +  T   +LRR      
Sbjct: 424  SCQEVPCPGTCSVLGGAHFSTFDGKQYTVHGDCSYVLTKPCDSSAFTVLAELRRCGLTDS 483

Query: 91   DGSISRIIVEL-GASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQ--LE 147
            +  +  + + L GA  V V +A   V  +  I      +   +T F  S   +  Q  L 
Sbjct: 484  ETCLKSVTLSLDGAQTVVVIKASGEV-FLNQIYTQLPISAANVTIFRPSTFFIIAQTSLG 542

Query: 148  LELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLD 207
            L+L +   P   L + +  K  GQ CGLCGNF+    ++F +  G               
Sbjct: 543  LQLNLQLVPTMQLFMQLAPKLRGQTCGLCGNFNSIQADDFRTLSG--------------- 587

Query: 208  DPGEICTFQDIPSTHVRQAQHARICTQLLTLVAPECSVSKEPFVLSCQADVAAAPQPGPQ 267
                           V +A  A       T  A  C   +  F   C   V  AP+ G  
Sbjct: 588  ---------------VVEATAAAFFNTFKTQAA--CPNIRNSFEDPCSLSVENAPRMGAP 630

Query: 268  NSSCATLSEYSRQCSMVGQ-----PVR-RWRSPGLCSVGQCPANQVYQECGSACVKTCSN 321
             S+C TL        +V Q     PV   W + G    G  P                S+
Sbjct: 631  -SACRTLVLALAAMLVVPQAETQGPVEPSWENAGHTMDGGAPT---------------SS 674

Query: 322  PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRC 381
            P    S       F P  TV   LS     +P+     V         ++ +        
Sbjct: 675  PTRRVS-------FVPPVTVFPSLSRKQ-MLPLPAGKGVFASPKGGGPDLGVQLPPALNP 726

Query: 382  TLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDK 441
                 VC         S  G     TFD   +RF G C Y+  +  +   +     V  +
Sbjct: 727  AHNGRVC---------STWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYED--FNVQLR 775

Query: 442  SGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMAT 501
             G+  S   +  VV +  Q  ++ + +  V  NG+ + LPY    + V  Q+  ++++  
Sbjct: 776  RGLVGSRPVVTRVV-IKAQGLVLEASNGSVLINGQREELPYSRTGLLV-EQSGDYIKV-- 831

Query: 502  SFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNG-DTTDDFTTSMGIAEGTASLFVD 560
            S  L L         A + + P++  QT GLCG+FNG    ++F      A       + 
Sbjct: 832  SIRLVLTFLWNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEF-----YAHNARLTPLQ 886

Query: 561  SWRAGNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVY 620
                       E+  DP  +   N    E  C   L  G  F  CHA V+   +   C  
Sbjct: 887  FGNLQKLDGPTEQCPDPLPLPAGNCTDEEGICHRTL-LGPAFAECHALVDSTAYLAACAQ 945

Query: 621  QACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERT 680
              C    T P  CA   +Y   C+  G     WR   + C   C  N         C  T
Sbjct: 946  DLCRC-PTCP--CATFVEYSRQCAHAGGQPRNWRCP-ELCPRTCPLNMQHQECGSPCTDT 1001

Query: 681  CLSLSDRATECHHSAVPVDGCNCPDG---TYLNQ--KGECVRKAQCPCILEGYKFILAEQ 735
            C S   RA  C      VDGC CP G   T L+      C+   QCPC   G  +     
Sbjct: 1002 C-SNPQRAQLCEDHC--VDGCFCPPGRSCTVLDDITHSGCLPLGQCPCTHGGRTY---SP 1055

Query: 736  STVINGI--TCHCINGRLSCPQRP 757
             T  N    +C C  G   C   P
Sbjct: 1056 GTSFNTTCSSCTCSGGLWQCQDLP 1079



 Score =  103 bits (258), Expect = 2e-21
 Identities = 129/541 (23%), Positives = 189/541 (34%), Gaps = 80/541 (14%)

Query: 379  CRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAV 438
            C C  GR +    P  G CS+ GGS  +TFD   Y F G CTY+L++       G L   
Sbjct: 5395 CECVGGRGIT---PGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHA-RFGNLSLY 5450

Query: 439  YDKSGVSHSETSLVAVVYLSR--------------------QDKIVISQDEVVTNNGEAK 478
             D    + S T+  A     R                    +++ +I  D++  ++G +K
Sbjct: 5451 LDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSK 5510

Query: 479  -WLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFN 537
              +       T  R     L ++ +F  +       +FQA +     F   T G CG   
Sbjct: 5511 NGVLVSVLGTTTMRVDIPALGVSVTFNGQ-------VFQARLPYS-LFHNNTEGQCGTCT 5562

Query: 538  GDTTDDFTTSMGIAEGTASLFVDSW-----RAGNCPAALERETDPCSMSQLNKVCAETHC 592
             +  DD     G    +      +W     R   C A           + ++     T C
Sbjct: 5563 NNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPC 5622

Query: 593  SML----LRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGV 648
                   L    VF  CH  V P PF+  C+   C      P  C +L  Y   C  RGV
Sbjct: 5623 PPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHCRGRLEVP--CQSLEAYAELCRARGV 5680

Query: 649  LLWGWRSSVDN-CTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGT 707
                WR +    C + C     +         TC S  +++ +    A   +GC CP+  
Sbjct: 5681 CS-DWRGATGGLCDLTCPPTKVYKPCGPIQPATCNS-RNQSPQLEGMA---EGCFCPEDQ 5735

Query: 708  YL--NQKGECVRKAQCPCI-LEGYKFILAEQSTVINGITCHCINGRLSCPQRP-----QM 759
             L     G CV+   CPC+  +G+     E+  V N  +C C  G +S   +P     Q 
Sbjct: 5736 ILFNAHMGICVQ--ACPCVGPDGFPKFPGER-WVSNCQSCVCDEGSVSVQCKPLPCDAQG 5792

Query: 760  FLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPT--KCEPGCVCAEGLYENA 817
                C  P         +EN     C P    +     C  +   C PG    E +    
Sbjct: 5793 QPPPCNRPGFVTVTRPRAEN----PCCPETVCVCNTTTCPQSLPVCPPG---QESICTQE 5845

Query: 818  DGQCVPPEECP---CEFSGVSYPGGAEL--HTDCRTCSCSRG-----RWACQQGTHCPST 867
            +G C P   C    C ++G  Y  GA       C  C+C  G        CQ+     +T
Sbjct: 5846 EGDCCPTFRCRPQLCSYNGTFYGVGATFPGALPCHMCTCLSGDTQDPTVQCQEDACNNTT 5905

Query: 868  C 868
            C
Sbjct: 5906 C 5906



 Score =  101 bits (251), Expect = 1e-20
 Identities = 105/406 (25%), Positives = 163/406 (40%), Gaps = 62/406 (15%)

Query: 828  PCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFD 887
            P + S  S P   + H +C  C C  GR      T     C+++G  H  TFDG  + F 
Sbjct: 5377 PIKVSDPSQP--CDFHYECE-CECVGGRGI----TPGAGICSMWGGSHYSTFDGTSYTFR 5429

Query: 888  GNCEYILATDVCGVNDSQPTF---KILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNY 944
            GNC Y+L  ++     +   +      T +     +   C RA+ I    + +VL     
Sbjct: 5430 GNCTYVLMREIHARFGNLSLYLDNHYCTASATAAAAAARCPRALSIHYKSMDIVLTVT-- 5487

Query: 945  TVTGEEPHV----QLGVTPGALSLVVDISIPGRYNLTL---IWNRHMTILIRIARAS--- 994
             V G+E  +    Q+ V+ G     V +S+ G   + +        +T   ++ +A    
Sbjct: 5488 MVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMRVDIPALGVSVTFNGQVFQARLPY 5547

Query: 995  ---QDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDVSFV---TDPCS 1048
                +   G CG    N +DD   R    A+S  ++  +W       D  +    T P +
Sbjct: 5548 SLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDMAKTWLVPDSRKDGCWAPTGTPPTA 5607

Query: 1049 LNAFRRSWA--------ERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCEC 1100
              A   S          +  C ++ SQ FA CH+ V   P++ AC+ D C     G  E 
Sbjct: 5608 SPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLVPPGPFFNACISDHC----RGRLEV 5663

Query: 1101 LCDAVAAYAQACLDKGVCVDWR--TPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQ 1158
             C ++ AYA+ C  +GVC DWR  T   C + C     +   G                Q
Sbjct: 5664 PCQSLEAYAELCRARGVCSDWRGATGGLCDLTCPPTKVYKPCG--------------PIQ 5709

Query: 1159 PCLCPSQPQSVPGSNI-EGCYNCSQDE-YFDHEEGVCV---PCMPP 1199
            P  C S+ QS     + EGC+ C +D+  F+   G+CV   PC+ P
Sbjct: 5710 PATCNSRNQSPQLEGMAEGCF-CPEDQILFNAHMGICVQACPCVGP 5754



 Score = 99.4 bits (246), Expect = 4e-20
 Identities = 100/393 (25%), Positives = 147/393 (37%), Gaps = 58/393 (14%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFA--------------------------ATCK 76
            G C  +G GHF TFD   Y F G+C YI A                           TC 
Sbjct: 1552 GTCVAYGDGHFITFDGDRYSFEGSCEYILAQDYCGDNTTHGTFRIVTENIPCGTTGTTCS 1611

Query: 77   DAFPTFSVQLRRGPDGSISRIIVELGA---SVVTVSEAIISVKDIGVISLPYTSNGLQIT 133
             A   F V++R  P  S         A   + V   + +  ++   +I    T   +   
Sbjct: 1612 KAIKLF-VEVRTAPAVSTPDPAANEPAPREASVGFRQRLPPLQSYELILQEGTFKAVARG 1670

Query: 134  PFGQ---SVRLVAKQLELE---LEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEF 187
            P G     +R +   L +E   + V W   + + + + + Y G++CGLCGNFD    N+F
Sbjct: 1671 PGGDPPYKIRYMGIFLVIETHGMAVSWDRKTSVFIRLHQDYKGRVCGLCGNFDDNAINDF 1730

Query: 188  VSEEGKFL-EPHKFAALQKLDD--PGEICTFQDIPSTHVRQAQHARICTQL--LTLVAPE 242
             +     + +  +F    KL    P  +       +   R++   + C+ L   T  A  
Sbjct: 1731 ATRSRSVVGDALEFGNSWKLSPSCPDALAPKDPCTANPFRKSWAQKQCSILHGPTFAACR 1790

Query: 243  CSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSV--- 299
              V    +  +C  D  A    G     C  ++ Y++ C   G  V  WR+P  C +   
Sbjct: 1791 SQVDSTKYYEACVNDACACDSGGDCECFCTAVAAYAQACHDAGLCV-SWRTPDTCPLFCD 1849

Query: 300  -----GQCPANQVYQECGSACVKTCSNPQHSCSSSC--TFGCFCPEGTVLNDLSNNHTCV 352
                 G C  +  YQ CG+ C+KTC NP   C        GC+ P+        N     
Sbjct: 1850 FYNPHGGCEWH--YQPCGAPCLKTCRNPSGHCLVDLPGLEGCY-PKCPPSQPFFNEDQMK 1906

Query: 353  PVTQCPCV-LHGAMYAPGE--VTIAACQTCRCT 382
             V QC C    G  Y  G    T   CQ+C CT
Sbjct: 1907 CVAQCGCYDKDGNYYDVGARVPTAENCQSCNCT 1939



 Score = 99.0 bits (245), Expect = 5e-20
 Identities = 124/433 (28%), Positives = 168/433 (38%), Gaps = 80/433 (18%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASP----TQTPLL 1255
            T     +T    T  S P   W +T  STT  +   TG + +++ T A+       T   
Sbjct: 4900 TATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTAT 4959

Query: 1256 PATLTSSKPTASSGE------PPRPTTAVTPQATS--GLP----------------PTAT 1291
              T+TSSK T SS        P   +TA TP ATS   +P                PTAT
Sbjct: 4960 TPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTAT 5019

Query: 1292 LRS-----------TATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPT------- 1333
            + +           T+T  T T  TT AT S A+P++T     TT+   T  T       
Sbjct: 5020 MSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPS 5079

Query: 1334 --PATSGTSP-TLPKST-----NQELPGTTATQT-----------TGPRPTPASTTGPTT 1374
              P T+ T P T P ST         P TT T T           T    TP+ST G T 
Sbjct: 5080 SSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTR 5139

Query: 1375 PQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYP 1434
                  T  T T  T + T T  +TP T      P T  + +  TG  TAT   A++T  
Sbjct: 5140 ILTELTTTATTTAATGS-TATLSSTPGTTWILTEPSTIATVMVPTGS-TAT---ASSTLG 5194

Query: 1435 TPSHPETTLPTHVPPFSTSLVTPSTHTV-ITPTHAQMATSASNHSAPTGTIPPPTTLKAT 1493
            T   P+        P +T+   PS+ TV  T T A + +S    S  T +    TTL+ T
Sbjct: 5195 TAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPT 5254

Query: 1494 G--STHTAPPITPTTSGTSQAHSSFSTNKTP-TSLHSHTSSTHHPEV------TPTSTTT 1544
            G  S+H + P      G   +      NKT     H +     H ++       PTS   
Sbjct: 5255 GFPSSHFSTPCFCRAFGQFFSPGEVIYNKTDRAGCHFYAVCNQHCDIDRFQGACPTSPPP 5314

Query: 1545 ITPNPTSTRTRTP 1557
            ++  P S+ +  P
Sbjct: 5315 VSSAPLSSPSPAP 5327



 Score = 97.8 bits (242), Expect = 1e-19
 Identities = 99/372 (26%), Positives = 147/372 (39%), Gaps = 34/372 (9%)

Query: 397 CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVY 456
           CS  G     TFD   +RF G C Y+  +           A Y+   +    +   A   
Sbjct: 81  CSTWGSFHYKTFDGDVFRFPGLCNYVFSEH--------CGAAYEDFNIQLRRSQESAAPT 132

Query: 457 LSRQ----DKIVISQDE-VVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQL 511
           LSR     D +VI   +  V  NG    LP+    + + +Q+S++ ++    GL  V+  
Sbjct: 133 LSRVLMKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLI-QQSSSYTKVEARLGL--VLMW 189

Query: 512 RPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAAL 571
                  + +  ++  +T GLCG+FNG        S  ++  T    ++           
Sbjct: 190 NHDDSLLLELDTKYANKTCGLCGDFNGMPV----VSELLSHNTKLTPMEFGNLQKMDDPT 245

Query: 572 ERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEET--F 629
           E+  DP      N       C  LL  G +F  C A V+   + + C    C  E+T   
Sbjct: 246 EQCQDPVPEPPRNCSTGFGICEELLH-GQLFSGCVALVDVGSYLEACRQDLCFCEDTDLL 304

Query: 630 PHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS-DRA 688
             +C  L +Y   C+  G L   WR   D C   C  N  +      C  TC +    RA
Sbjct: 305 SCVCHTLAEYSRQCTHAGGLPQDWRGP-DFCPQKCPNNMQYHECRSPCADTCSNQEHSRA 363

Query: 689 TECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCILEGYKFILAEQSTVINGIT-CH 745
            E H  A    GC CP+GT L+  G+  CV  ++C C+  G  +  A  +T     T C 
Sbjct: 364 CEDHCVA----GCFCPEGTVLDDIGQTGCVPVSKCACVYNGAAY--APGATYSTDCTNCT 417

Query: 746 CINGRLSCPQRP 757
           C  GR SC + P
Sbjct: 418 CSGGRWSCQEVP 429



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 78/282 (27%), Positives = 120/282 (42%), Gaps = 32/282 (11%)

Query: 863  HCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGV 922
            H    C+ +G  H  TFDG  F F G C Y+ + + CG        ++        ++  
Sbjct: 76   HNGRVCSTWGSFHYKTFDGDVFRFPGLCNYVFS-EHCGAAYEDFNIQLRRSQE---SAAP 131

Query: 923  TCSRAIKIFLGGLSVVLADRNYTVTGEE---PHVQLGVTPGALSLVVDISIPGRYNLTLI 979
            T SR + + + G+ + L   +  V G     P  Q GV     S    +    R  L L+
Sbjct: 132  TLSRVL-MKVDGVVIQLTKGSVLVNGHPVLLPFSQSGVLIQQSSSYTKVE--ARLGLVLM 188

Query: 980  WNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL-CG 1038
            WN   ++L+ +     +  CGLCG+FNG               SEL L ++ K +P+  G
Sbjct: 189  WNHDDSLLLELDTKYANKTCGLCGDFNG-----------MPVVSEL-LSHNTKLTPMEFG 236

Query: 1039 DVSFVTDPCSLNAFRRSWAERKCS--------VINSQTFATCHSKVYHLPYYEACVRDAC 1090
            ++  + DP            R CS        +++ Q F+ C + V    Y EAC +D C
Sbjct: 237  NLQKMDDPTEQCQDPVPEPPRNCSTGFGICEELLHGQLFSGCVALVDVGSYLEACRQDLC 296

Query: 1091 GCDSGGDCECLCDAVAAYAQACLDK-GVCVDWRTPAFCPIYC 1131
             C+      C+C  +A Y++ C    G+  DWR P FCP  C
Sbjct: 297  FCEDTDLLSCVCHTLAEYSRQCTHAGGLPQDWRGPDFCPQKC 338



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 81/322 (25%), Positives = 126/322 (39%), Gaps = 35/322 (10%)

Query: 863  HCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGV 922
            H    C+ +G+ H  TFDG  F F G C Y+ +       +    F +     + G+  V
Sbjct: 728  HNGRVCSTWGDFHYKTFDGDVFRFPGLCNYVFSEHCRAAYED---FNVQLRRGLVGSRPV 784

Query: 923  TCSRAIKIFLGGLSVVLADRNYTVTGEE---PHVQLGVTPGALSLVVDISIPGRYNLTLI 979
                 IK    GL +  ++ +  + G+    P+ + G+        + +SI  R  LT +
Sbjct: 785  VTRVVIKA--QGLVLEASNGSVLINGQREELPYSRTGLLVEQSGDYIKVSI--RLVLTFL 840

Query: 980  WNRHMTILIRIARASQDPLCGLCGNFNG-NMKDDFETRSRYVASSELELVNSWKESPLCG 1038
            WN   + L+ +     +  CGLCG+FNG    ++F     Y  ++ L  +       L G
Sbjct: 841  WNGEDSALLELDPKYANQTCGLCGDFNGLPAFNEF-----YAHNARLTPLQFGNLQKLDG 895

Query: 1039 DVSFVTDPCSLNAFRRSWAERKC-SVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGD 1097
                  DP  L A   +  E  C   +    FA CH+ V    Y  AC +D C C +   
Sbjct: 896  PTEQCPDPLPLPAGNCTDEEGICHRTLLGPAFAECHALVDSTAYLAACAQDLCRCPT--- 952

Query: 1098 CECLCDAVAAYAQACLDK-GVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWH 1156
              C C     Y++ C    G   +WR P  CP  C     H + G         + CT  
Sbjct: 953  --CPCATFVEYSRQCAHAGGQPRNWRCPELCPRTCPLNMQHQECG---------SPCT-- 999

Query: 1157 YQPCLCPSQPQSVPGSNIEGCY 1178
               C  P + Q      ++GC+
Sbjct: 1000 -DTCSNPQRAQLCEDHCVDGCF 1020



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 87/275 (31%), Positives = 121/275 (44%), Gaps = 39/275 (14%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPL 1254
            P    +T  P +TP+   T +  T     TG + ++   SST   P + HT   PT T  
Sbjct: 5016 PTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSST---PGTAHTTKVPTTTTT 5072

Query: 1255 -LPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTA 1313
               AT +SS  TA +     P + ++   TS  P T     T+T  T T   TRAT STA
Sbjct: 5073 GFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETT---HTSTVLTTTATMTRATNSTA 5129

Query: 1314 SPATT-STAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372
            +P++T  T +  T  T T  T A +G++ TL  +     PGTT   T    P+  +T   
Sbjct: 5130 TPSSTLGTTRILTELTTTATTTAATGSTATLSST-----PGTTWILT---EPSTIATV-- 5179

Query: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTA-GSPVPSTGPVTATSFHATT 1431
                      PT +  T + T     TP+   T  + PTA  S VPS+  V  T      
Sbjct: 5180 --------MVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVGTTR----- 5226

Query: 1432 TYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPT 1466
               TP+     LP+ +P FS S V+ S  T + PT
Sbjct: 5227 ---TPA----VLPSSLPTFSVSTVSSSVLTTLRPT 5254



 Score = 87.0 bits (214), Expect = 2e-16
 Identities = 99/400 (24%), Positives = 143/400 (35%), Gaps = 50/400 (12%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLR------------ 87
            P  G CS WG  H+STFD   Y F G C Y+        F   S+ L             
Sbjct: 5405 PGAGICSMWGGSHYSTFDGTSYTFRGNCTYVLMREIHARFGNLSLYLDNHYCTASATAAA 5464

Query: 88   ------RGPDGSISRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRL 141
                  R        + + L  ++V   E  + + D   +S  ++ NG+ ++  G +   
Sbjct: 5465 AAARCPRALSIHYKSMDIVLTVTMVHGKEEGLILFDQIPVSSGFSKNGVLVSVLGTTTMR 5524

Query: 142  VAKQLELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGK-------- 193
            V     L + V +        L    +     G CG       ++ +  +G         
Sbjct: 5525 VDIPA-LGVSVTFNGQVFQARLPYSLFHNNTEGQCGTCTNNQRDDCLQRDGTTAASCKDM 5583

Query: 194  ---FLEP--HKFAALQKLDDPGEICTFQDIPSTHV-RQAQHARICTQLLTLVAPECS--V 245
               +L P   K         P        + ST          +C  +L+ V  EC   V
Sbjct: 5584 AKTWLVPDSRKDGCWAPTGTPPTASPAAPVSSTPTPTPCPPQPLCDLMLSQVFAECHNLV 5643

Query: 246  SKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSP--GLCSVGQCP 303
               PF  +C +D        P    C +L  Y+  C   G     WR    GLC +  CP
Sbjct: 5644 PPGPFFNACISDHCRGRLEVP----CQSLEAYAELCRARGV-CSDWRGATGGLCDL-TCP 5697

Query: 304  ANQVYQECGSACVKTCSNPQHSCS-SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCV-L 361
              +VY+ CG     TC++   S        GCFCPE  +   L N H  + V  CPCV  
Sbjct: 5698 PTKVYKPCGPIQPATCNSRNQSPQLEGMAEGCFCPEDQI---LFNAHMGICVQACPCVGP 5754

Query: 362  HGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEG 401
             G    PGE  ++ CQ+C C  G      +P P  C  +G
Sbjct: 5755 DGFPKFPGERWVSNCQSCVCDEGSVSVQCKPLP--CDAQG 5792



 Score = 76.3 bits (186), Expect = 4e-13
 Identities = 117/432 (27%), Positives = 176/432 (40%), Gaps = 83/432 (19%)

Query: 1997 TPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056
            TP+   T +P+          TP T  ++    T   T+ S  ST T +  P TT   T 
Sbjct: 3055 TPATSSTAMPSS---------TPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTE 3105

Query: 2057 STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSR--PPSSPIT-TQLPH 2113
             + TA   TVT    S   +S + ATA +  +S+++  P  +SS+  P SSP T T LP 
Sbjct: 3106 PSTTA---TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPA 3162

Query: 2114 L-SSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHS 2172
            L S+ATTP +T      SF+  PS+ S  +++   S ++  T++ S  T SS     VH+
Sbjct: 3163 LRSTATTPTAT------SFTAIPSS-SLGTTWTRLSQTTTPTATMSTATPSS-TPETVHT 3214

Query: 2173 TTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVT 2232
            +T+       L+T  TT   + S                                    T
Sbjct: 3215 STV-------LTTTATTTGATGS----------------------------------VAT 3233

Query: 2233 VSPTPSSH-----LASSTIAFPSTPRTTAST-HTAPAFSSQSTTSRSTSLTTRVPTSGFV 2286
             S TP +      L ++T  F +TP ++  T  T P + S +TT+ +T  +T  P+S   
Sbjct: 3234 PSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIS-TTTTPTTRGSTVTPSS--- 3289

Query: 2287 SLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSP 2346
                G T  PT   T  TT   G   +P++   TS  T     P +   +   + +P+SP
Sbjct: 3290 --IPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSP 3347

Query: 2347 GVCSVREQQEEITFKGCMANVTVTR-CEGACISAASFNIITQQVDARCSCCRPLHSYEQQ 2405
               +VR      T  G +    +T    G   + A+    TQ      S   P  S    
Sbjct: 3348 H--TVRTAWTSAT-SGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHP--SSRTT 3402

Query: 2406 LELPCPDPSTPG 2417
               P P  +TPG
Sbjct: 3403 ESPPSPGTTTPG 3414



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 9/90 (10%)

Query: 2349 CSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLEL 2408
            C VR     +  +GC   V +T CEG+C  A+ ++   Q +  +C+CC+    +E+ + L
Sbjct: 5995 CQVRINTTILWHQGCETEVNITFCEGSCPGASKYSAEAQAMQHQCTCCQERRVHEETVPL 6054

Query: 2409 PCPDPSTPGRRLVLTLQVFSHCVCSSVACG 2438
             CP+ S         L  ++H V   V CG
Sbjct: 6055 HCPNGSA-------ILHTYTHAV--QVLCG 6075


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score =  817 bits (2110), Expect = 0.0
 Identities = 563/1663 (33%), Positives = 790/1663 (47%), Gaps = 171/1663 (10%)

Query: 384  GRW-VCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442
            G W   T    PG      G+ V      P     TC+++ + S  L E+  +   +   
Sbjct: 283  GNWRTATSAVSPGASKTCPGNLVYLESGSPCM--DTCSHLEVSS--LCEEHRMDGCFCPE 338

Query: 443  GVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502
            G        V ++   +++ +V   D  V  N     LP+ T + +VFR +S H+ ++ +
Sbjct: 339  GAQADLPKTVVLLADKKKNVVVFKSDGSVLLNELQVNLPHVTASFSVFRPSSYHIMVSMA 398

Query: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSW 562
             G+ L VQL P+ Q +VT+    +GQ +GLCGNFNG   DDF T+ G+ E T + F ++W
Sbjct: 399  IGVRLQVQLAPVMQLFVTLDQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTW 458

Query: 563  RA-GNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQ 621
            +A  +C   L+   DPCS++  +   AE  CS+L +T T F RCH+ V+PA +YKRC Y 
Sbjct: 459  KAQSSCHDKLDWLDDPCSLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYD 518

Query: 622  ACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTI-PCTGNTTFSYNSQACERT 680
             CN +     +CAAL  Y  AC+ +GV+LWGWR  V N  +  C  +  F YN   C++T
Sbjct: 519  TCNCQNNEDCLCAALSSYARACTAKGVMLWGWREHVCNKDVGSCPNSQVFLYNLTTCQQT 578

Query: 681  CLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVIN 740
            C SLS+  + C     PVDGC CPD T+L++KG CV  A+C C   G  ++ A    V  
Sbjct: 579  CRSLSEADSHCLEGFAPVDGCGCPDHTFLDEKGRCVPLAKCSCYHRGL-YLEAGDVVVRQ 637

Query: 741  GITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVP 800
               C C +GRL C Q  ++   SC APK    CS  +        A +CQ LA G     
Sbjct: 638  EERCVCRDGRLHCRQI-RLIGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGY--YH 694

Query: 801  TKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQ 860
            T+C  GCVC +GL ++  G CV  +ECPC  +   Y  GA++  DC TC+C RGRW C Q
Sbjct: 695  TECVSGCVCPDGLMDDGRGGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQ 754

Query: 861  GTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNS 920
               C  TC++YG GH ITFDG+ + FDG+C Y+   D CG N S  +F I+TENV CG +
Sbjct: 755  AV-CHGTCSIYGSGHYITFDGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTT 813

Query: 921  GVTCSRAIKIFLGGLSVVLADRNYTVT--GEEPHVQLGVTPGALSLVVDISIPGRYNLTL 978
            GVTCS+AIKIF+G   + L D++  V    E  HV          LVV+ S      + +
Sbjct: 814  GVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESST----GIIV 869

Query: 979  IWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCG 1038
            IW++  T+ I++A + +  +CGLCGNF+    +DF TR   V SSEL+  NSWKE+P C 
Sbjct: 870  IWDKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCP 929

Query: 1039 DVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDC 1098
            DVS   +PCSLN  RRSWAE++CS++ S  F+ CHSKV   P+YEACV D+C CD+GGDC
Sbjct: 930  DVSTNPEPCSLNPHRRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDC 989

Query: 1099 ECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQ 1158
            EC C AVA+YAQ C  +G CV WRTP  CPI+C +YN   +             C WHY+
Sbjct: 990  ECFCSAVASYAQECTKEGACVFWRTPDLCPIFCDYYNPPHE-------------CEWHYE 1036

Query: 1159 PC---------LCPSQPQSVPGSNIEGCY-NCSQDE-YFDHEEGVCVP-----CMPPTTP 1202
            PC                ++  S +EGCY  C +D   ++ +   CV      C    T 
Sbjct: 1037 PCGNRSFETCRTINGIHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVEDTH 1096

Query: 1203 QPP--TTPQLPTTGS-----------RPTQ-------------VWPMTGTSTTI----GL 1232
             PP  + P   T  S           RP +              W + G + T+     +
Sbjct: 1097 YPPGASVPTEETCKSCVCTNSSQVVCRPEEGKILNQTQDGAFCYWEICGPNGTVEKHFNI 1156

Query: 1233 LS-STGPSPSSNHTPAS-PTQTPLLPATLTSSKPTASSGEPPRPTTAVT---------PQ 1281
             S +T PS  +  T  + PT       T T++ PT+S+     P              P 
Sbjct: 1157 CSITTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPS 1216

Query: 1282 ATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTL----PTPATS 1337
            + S      T       P   +  +      +        Q     ++ L          
Sbjct: 1217 SGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPG 1276

Query: 1338 GTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEY 1397
            G  P +    N E+        T P     +TT   TP P   T  T    T T T+T+ 
Sbjct: 1277 GVIP-MAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTP--ITTTTTVTPTPTPTSTQS 1333

Query: 1398 TTP----QTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTS 1453
            TTP     T   T +P   G+  P+T P+T T    TT  PTP+   T  PT  P  +T+
Sbjct: 1334 TTPTPITTTTTVTPTPTPTGTQTPTTTPITTT----TTVTPTPTPTGTQTPTTTPITTTT 1389

Query: 1454 LVTPSTHTVITPTHAQMATS--------ASNHSAPTGTIPPPTTLKATGSTHTAPPITPT 1505
             VTP+     TPT  Q  TS         +    PTGT  P TT   T +T T  P    
Sbjct: 1390 TVTPTP----TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1445

Query: 1506 TSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSAT 1565
            T   +    + ++  TPT   + T +     +T T+T T TP PT T+T TP A T + T
Sbjct: 1446 TQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTT 1505

Query: 1566 SSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVT 1625
             +  P P  T +P   S+P ++          TTT  PTP+   T  PT  P  +T+ VT
Sbjct: 1506 VTPTPTPTGTQTPT--STPITT----------TTTVTPTPTPTGTQTPTPTPISTTTTVT 1553

Query: 1626 PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLT-TSGTSQALSS 1684
            P      TPT             PTGT   PTT   T +T   PT T T T   +  L +
Sbjct: 1554 P------TPT-------------PTGT-QTPTTTPITTTTTVTPTPTPTGTQTPTTVLIT 1593

Query: 1685 LNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPM-TVTTSGTSQSRSSFSTA 1743
              T  T T   + T ST     T+T+T   TP PT T TP M  ++T+ T     + +T 
Sbjct: 1594 TTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTG 1653

Query: 1744 KTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT-PFTTHSP 1802
             T    H+ T+       ++    S TP  TS  T +P+  +T+  S+  P    T+ +P
Sbjct: 1654 STGPPTHTSTAPIAELTTSNPPPESSTP-QTSRSTSSPLTESTTLLSTLPPAIEMTSTAP 1712

Query: 1803 P-TGTTPISSTGPVTATSFQTTTTYP--TPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPT 1859
            P T T P +++G  T +   +TTT P  TP+   TT  +  P+ ST  V  +T +   PT
Sbjct: 1713 PSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPST--VQTTTTSAWTPT 1770

Query: 1860 HTQMATSASIHSMPTGTIPPPTTIK---ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTST 1916
             T ++T + I +  TG  P P+++        T+ AP      +GT      F     S 
Sbjct: 1771 PTPLSTPSIIRT--TGLRPYPSSVLICCVLNDTYYAPG-EEVYNGTYGDTCYFVNCSLSC 1827

Query: 1917 SLPYHT---SSTHHPEVTPTSTT------NITPKHTSTGTRTP 1950
            +L ++     ST  P  TP+ +T      + TP   + GT+ P
Sbjct: 1828 TLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 1870



 Score =  212 bits (540), Expect = 3e-54
 Identities = 204/655 (31%), Positives = 289/655 (44%), Gaps = 112/655 (17%)

Query: 1484 IPPPTTLKATGSTHTAP-PITPTTSGTSQAHSSFSTNKTPTSLHSHTS--------STHH 1534
            +  PTT+  T + +  P PIT TT+ T     + + + TPT + + T+         T  
Sbjct: 1297 VTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQT 1356

Query: 1535 PEVTP-TSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTA 1593
            P  TP T+TTT+TP PT T T+TP     + T++  P P      PTG+   +ST P+T 
Sbjct: 1357 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTST-PITT 1410

Query: 1594 TSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIT--PTHAQMATSASIHSMPTG 1651
                TTT  PTP+   T  PT  P  +T+ VTP+     T  PT   + T++++   PT 
Sbjct: 1411 ----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTP 1466

Query: 1652 T-IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTS 1710
            T    PTT   T +T   PT T T + T    +++ T  T T   + T +        T+
Sbjct: 1467 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTP-TAITTTTTVTPTPTPTGTQTPTSTPITT 1525

Query: 1711 TTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSIT 1770
            TT +TP PT TGT   T T           ST  T T   + T +        T+TT++T
Sbjct: 1526 TTTVTPTPTPTGTQTPTPT---------PISTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1576

Query: 1771 PNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPS 1830
            P  T TGT+TP     + T++  PTP  T +  T  TPI++T  VTAT        PTP+
Sbjct: 1577 PTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT--------PTPT 1628

Query: 1831 HPHTTLPTHVPSFSTSLV----TPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKAT 1886
               T  PT +P  +T+ V    TP+T +   PTHT  A  A +    T + PPP +    
Sbjct: 1629 GTQT--PTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAEL----TTSNPPPES---- 1678

Query: 1887 GSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTG 1946
                     TP TS ++ SP + ST   ST  P    ++  P  TPT+ T          
Sbjct: 1679 --------STPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT---------- 1720

Query: 1947 TRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLP 2006
                   TTS   +  P P TT SPP   +  ++TG  +A         PTPS  QTT  
Sbjct: 1721 -------TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA---------PTPSTVQTTTT 1764

Query: 2007 THVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLK---ATGSTHTAPP 2063
            +   P  T L TPS    II T              TG  P P+++        T+ AP 
Sbjct: 1765 SAWTPTPTPLSTPS----IIRT--------------TGLRPYPSSVLICCVLNDTYYAPG 1806

Query: 2064 MTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSAT 2118
              V  +GT      F   + S + +   +W   ++ S  P+   +T  P   S+T
Sbjct: 1807 EEV-YNGTYGDTCYFVNCSLSCT-LEFYNWSCPSTPSPTPTPSKSTPTPSKPSST 1859



 Score =  204 bits (519), Expect = 9e-52
 Identities = 241/859 (28%), Positives = 352/859 (40%), Gaps = 135/859 (15%)

Query: 1587 STGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSL-VTPSTHTV----ITPTHAQMAT 1641
            +T P T T+F T T   TP+   TT  T  P  ST L  TP    +    I   H    +
Sbjct: 1160 TTRPSTLTTFTTITLPTTPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWINEDHPSSGS 1219

Query: 1642 SASIHSMPTGTIPPPTTL--KATGSTHTA-------------PTMTLTTSGTSQALSSLN 1686
                     G    P  +  ++    H +              ++ L      Q    + 
Sbjct: 1220 DDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNEDQKPGGVI 1279

Query: 1687 TAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS 1746
                  +   +          +T TT  T NPT T   P+T TT+ T     + + + T 
Sbjct: 1280 PMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPT---PITTTTTVTPTPTPTSTQSTTP 1336

Query: 1747 TSLHSHTSSTHHPEVTS---------TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPF 1797
            T + + T+ T  P  T          T+TT++TP  T TGT+TP     + T++  PTP 
Sbjct: 1337 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP- 1395

Query: 1798 TTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS-THT-V 1855
                 PTGT   +ST P+T     TTT  PTP+   T  PT  P  +T+ VTP+ T T  
Sbjct: 1396 ----TPTGTQTPTST-PITT----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1446

Query: 1856 IIPTHTQMATSASIHSMPTGT-IPPPTTIKATGSTHTAPPMTPTTSGT-SQSPSSFSTAK 1913
              PT T + T++++   PT T    PTT   T +T   P  TPT +GT + +P++ +T  
Sbjct: 1447 QAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQTPTPTAITTTT 1504

Query: 1914 TSTSLPYHTSSTHHPEVTP-TSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPP 1972
            T T  P  T  T  P  TP T+TT +TP  T TGT+TP     S +++  PTP      P
Sbjct: 1505 TVTPTPTPT-GTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTP-----TP 1558

Query: 1973 TGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQM 2032
            TG+    +T P+T T+  T T  PTP+  QT     +   +T   TP+  +   TT T +
Sbjct: 1559 TGTQT-PTTTPITTTT--TVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPI 1615

Query: 2033 ATSASIHSTPTGT-VPPPTTLKATGSTHTAPPMTVTTSGTS-QTHSSFSTATASSSFISS 2090
             T+ ++ +TPT T    PT +  + +T   P  T TT  T   TH    T+TA  + +++
Sbjct: 1616 TTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTH----TSTAPIAELTT 1671

Query: 2091 SSWLPQNS---SSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPS 2147
            S+  P++S   +SR  SSP+T     LS+    +  T+    S   +P+AP+T       
Sbjct: 1672 SNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPS---TPTAPTTT------ 1722

Query: 2148 SHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTT 2207
              S   T SP   T++S    P   TT  S S  + ST  TT + + +P           
Sbjct: 1723 --SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP----------- 1769

Query: 2208 IRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQ 2267
                      +P  LS    I T  + P PSS L    +           T+ AP     
Sbjct: 1770 ----------TPTPLSTPSIIRTTGLRPYPSSVLICCVL---------NDTYYAPGEEVY 1810

Query: 2268 STTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHG 2327
            + T   T        S  +   +      + P T      P PT +P      S  T   
Sbjct: 1811 NGTYGDTCYFVNCSLSCTLEFYNW-----SCPST------PSPTPTP------SKSTPTP 1853

Query: 2328 STPASAPVS-SLGTPTPTSPGVCSVREQQE-----EITFKGCMANVTV----TRCEGACI 2377
            S P+S P   + GT  P  P     R++ E     +     C  N TV      CE   +
Sbjct: 1854 SKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDCFMATCKYNNTVEIVKVECEPPPM 1913

Query: 2378 SAASFNIITQQVDARCSCC 2396
               S  +   +V+    CC
Sbjct: 1914 PTCSNGLQPVRVEDPDGCC 1932



 Score =  180 bits (456), Expect = 2e-44
 Identities = 134/462 (29%), Positives = 213/462 (46%), Gaps = 58/462 (12%)

Query: 299  VGQ-CPANQVYQECGSACVKTCSNPQH-SCSS--------SCTFGCFCPEGTVLNDLSNN 348
            +GQ C A +++ +C +      S P+  SC +         C  GC CP+G +++D    
Sbjct: 656  IGQSCTAPKIHMDCSNLTALATSKPRALSCQTLAAGYYHTECVSGCVCPDG-LMDD--GR 712

Query: 349  HTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTF 408
              CV   +CPCV +  +Y+ G      C TC C  GRWVCT+  C G CS+ G     TF
Sbjct: 713  GGCVVEKECPCVHNNDLYSSGAKIKVDCNTCTCKRGRWVCTQAVCHGTCSIYGSGHYITF 772

Query: 409  DARPYRFHGTCTYILLQS--PQLPEDGALMAVYDK--SGVSHSETSLVAVVYLSRQDKIV 464
            D + Y F G C+Y+ +Q    Q    G+   + +    G +    S    +++ R +  +
Sbjct: 773  DGKYYDFDGHCSYVAVQDYCGQNSSLGSFSIITENVPCGTTGVTCSKAIKIFMGRTELKL 832

Query: 465  ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQ 524
              +  VV    E   + Y TR +        +L + +S G+ ++   R     ++ + P 
Sbjct: 833  EDKHRVVIQRDEGHHVAYTTREV------GQYLVVESSTGIIVIWDKRT--TVFIKLAPS 884

Query: 525  FRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWR-AGNCPAALERETDPCSMSQL 583
            ++G   GLCGNF+  + +DFTT   +   +   F +SW+ A  CP  +    +PCS++  
Sbjct: 885  YKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCP-DVSTNPEPCSLNPH 943

Query: 584  NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYE-----ETFPHICAALGD 638
             +  AE  CS+L    +VF  CH+ V+P PFY+ CV+ +C+ +     E F   C+A+  
Sbjct: 944  RRSWAEKQCSIL--KSSVFSICHSKVDPKPFYEACVHDSCSCDTGGDCECF---CSAVAS 998

Query: 639  YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYN-SQACERTCLSLSDRATE-CH---- 692
            Y   C+  G  ++ WR+  D C I C       YN    CE       +R+ E C     
Sbjct: 999  YAQECTKEGACVF-WRTP-DLCPIFCD-----YYNPPHECEWHYEPCGNRSFETCRTING 1051

Query: 693  -HSAVPV---DGC--NCPDG--TYLNQKGECVRKAQCPCILE 726
             HS + V   +GC   CP     Y     +CV   +C C +E
Sbjct: 1052 IHSNISVSYLEGCYPRCPKDRPIYEEDLKKCVTADKCGCYVE 1093



 Score =  167 bits (422), Expect = 2e-40
 Identities = 103/312 (33%), Positives = 162/312 (51%), Gaps = 26/312 (8%)

Query: 45  CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGP-----DGSISRIIV 99
           CSTWG  H+ TFD  V+ F G C+Y FA+ C+ ++  F+V L+RGP        +  I++
Sbjct: 37  CSTWGNFHYKTFDGDVFRFPGLCDYNFASDCRGSYKEFAVHLKRGPGQAEAPAGVESILL 96

Query: 100 ELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159
            +    + ++   ++V +  V+S P+ S GL I       ++ ++     L ++W  +  
Sbjct: 97  TIKDDTIYLTRH-LAVLNGAVVSTPHYSPGLLIEKSDAYTKVYSR---AGLTLMWNREDA 152

Query: 160 LMVLVERKYMGQMCGLCGNFDG-KVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDI 218
           LM+ ++ K+    CGLCG+++G +  +EF+S +G    P +F  +QK++ P  +C   + 
Sbjct: 153 LMLELDTKFRNHTCGLCGDYNGLQSYSEFLS-DGVLFSPLEFGNMQKINQPDVVCEDPEE 211

Query: 219 PSTHVRQAQHARICTQLLTLVA-PECS--VSKEPFVLSCQADVAAAPQPGPQNSSCATLS 275
                  ++H   C +LLT  A  +C   V  EP++ +CQ D      PG     C+T++
Sbjct: 212 EVAPASCSEHRAECERLLTAEAFADCQDLVPLEPYLRACQQDRCRC--PGGDTCVCSTVA 269

Query: 276 EYSRQCSMVGQPVRRWR------SPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CS 327
           E+SRQCS  G     WR      SPG      CP N VY E GS C+ TCS+ + S  C 
Sbjct: 270 EFSRQCSHAGGRPGNWRTATSAVSPGASKT--CPGNLVYLESGSPCMDTCSHLEVSSLCE 327

Query: 328 SSCTFGCFCPEG 339
                GCFCPEG
Sbjct: 328 EHRMDGCFCPEG 339



 Score =  129 bits (324), Expect = 4e-29
 Identities = 133/433 (30%), Positives = 182/433 (42%), Gaps = 64/433 (14%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGS---RPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P   PT  Q PTT  + TT +    PT     T T T I   ++  P+P+   T  +PT 
Sbjct: 1462 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQ-TPTS 1520

Query: 1252 TPLLPATLTSSKPTASSGEPPRPT-----TAVTPQAT---SGLPPTATLRSTAT-----K 1298
            TP+   T  +  PT +  + P PT     T VTP  T   +  P T  + +T T      
Sbjct: 1521 TPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 1580

Query: 1299 PTVTQA-----TTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPG 1353
            PT TQ       T  T  T +P  TST +STT T +T  T  T+  +PT    T   +P 
Sbjct: 1581 PTGTQTPTTVLITTTTTMTPTPTPTST-KSTTVTPITTTTTVTATPTPT-GTQTPTMIPI 1638

Query: 1354 TTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAG 1413
            +T T  T   PTP  TTG T P     T P A E T +    E +TPQT  +T SP T  
Sbjct: 1639 STTTTVT---PTPTPTTGSTGPPTHTSTAPIA-ELTTSNPPPESSTPQTSRSTSSPLTES 1694

Query: 1414 SPVPSTGPVTATSFHATTTYPTPSHPETTLPTHV--PPFSTSLVTPSTHTVIT------- 1464
            + + ST P  A    +T    TP+ P TT   H   PP ST+   P T T  T       
Sbjct: 1695 TTLLSTLP-PAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSA 1753

Query: 1465 PTHAQMATSASNHSAPTGT-IPPPTTLKATG---------------STHTAP--PITPTT 1506
            PT + + T+ ++   PT T +  P+ ++ TG                T+ AP   +   T
Sbjct: 1754 PTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGT 1813

Query: 1507 SGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566
             G +    + S + T    +    ST  P  TP+ +T     P+ST ++         T 
Sbjct: 1814 YGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSK--------PTP 1865

Query: 1567 SRPPPPFTTHSPP 1579
               PP      PP
Sbjct: 1866 GTKPPECPDFDPP 1878



 Score =  104 bits (260), Expect = 9e-22
 Identities = 120/507 (23%), Positives = 183/507 (36%), Gaps = 70/507 (13%)

Query: 388  CTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQ--SPQLPEDGALMAVYDKSGVS 445
            C    C  +C+  G     TFD   Y + G CTY+L++  SP +   G  +  Y      
Sbjct: 1932 CWHWECDCYCTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPND 1991

Query: 446  HSETSLVAVVYLSRQDKIV-----ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMA 500
                    +V    Q+ ++     +     V  N +A  LPYK   + V++    ++   
Sbjct: 1992 KVSCPRTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDI 2051

Query: 501  TSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVD 560
               G  ++V    +  +      +F   T+G CG     T+DD     G          D
Sbjct: 2052 PELG--VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAAD 2109

Query: 561  SWRAG-----NCPAALERETDPC------SMSQLNKVCAETHCSMLLRTGTVFERCHATV 609
             W        +CP +      P         +  +K C  +    L++  ++F +CHA V
Sbjct: 2110 QWLVNDPSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIK-DSLFAQCHALV 2168

Query: 610  NPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDN-CTIPCTGNT 668
             P  +Y  CV+ +C +       CA+L  Y   C+ + + L  WR+     C + C  + 
Sbjct: 2169 PPQHYYDACVFDSC-FMPGSSLECASLQAYAALCAQQNICL-DWRNHTHGACLVECPSHR 2226

Query: 669  TFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGY 728
             +     A E TC S S +     ++ V V+GC CP+GT     G  V    C C+  G 
Sbjct: 2227 EYQACGPAEEPTCKSSSSQ----QNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCV--GP 2280

Query: 729  KFILAE--QSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
              +  E  +    +   C C+ G      +P             K CSQ    K    C 
Sbjct: 2281 DNVPREFGEHFEFDCKNCVCLEGGSGIICQP-------------KRCSQ----KPVTHCV 2323

Query: 787  PTCQMLATGVACVPTKCE-PGCVCAEGLYENADGQC----------VPPEECP---CEFS 832
                 LAT V    T C    C C   L +     C          VP   CP   CE  
Sbjct: 2324 EDGTYLATEVNPADTCCNITVCKCNTSLCKEKPSVCPLGFEVKSKMVPGRCCPFYWCESK 2383

Query: 833  GVSYPGGAELH-------TDCRTCSCS 852
            GV   G AE         + C+ C C+
Sbjct: 2384 GVCVHGNAEYQPGSPVYSSKCQDCVCT 2410



 Score =  104 bits (259), Expect = 1e-21
 Identities = 104/373 (27%), Positives = 159/373 (42%), Gaps = 49/373 (13%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELG 102
            G CS +G+GH+ TFD   YDF G C+Y+       A   +  Q       SI    V  G
Sbjct: 759  GTCSIYGSGHYITFDGKYYDFDGHCSYV-------AVQDYCGQNSSLGSFSIITENVPCG 811

Query: 103  ASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSV----RLVAKQLELE----LEVVW 154
             + VT S+AI        + L      +     G  V    R V + L +E    + V+W
Sbjct: 812  TTGVTCSKAIKIFMGRTELKLEDKHRVVIQRDEGHHVAYTTREVGQYLVVESSTGIIVIW 871

Query: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEF-------VSEEGKFLEPHKFA-ALQKL 206
               + + + +   Y G +CGLCGNFD +  N+F       VS E  F    K A     +
Sbjct: 872  DKRTTVFIKLAPSYKGTVCGLCGNFDHRSNNDFTTRDHMVVSSELDFGNSWKEAPTCPDV 931

Query: 207  DDPGEICTFQDIPSTHVRQAQHARICTQLLTLVAPEC--SVSKEPFVLSCQADVAAAPQP 264
                E C+     + H R++   + C+ L + V   C   V  +PF  +C  D  +    
Sbjct: 932  STNPEPCSL----NPH-RRSWAEKQCSILKSSVFSICHSKVDPKPFYEACVHDSCSCDTG 986

Query: 265  GPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSV--------GQCPANQVYQECGSACV 316
            G     C+ ++ Y+++C+  G  V  WR+P LC +         +C  +  Y+ CG+   
Sbjct: 987  GDCECFCSAVASYAQECTKEGACV-FWRTPDLCPIFCDYYNPPHECEWH--YEPCGNRSF 1043

Query: 317  KTCS--NPQHS-CSSSCTFGCF--CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGE- 370
            +TC   N  HS  S S   GC+  CP+   + +  +   CV   +C C +    Y PG  
Sbjct: 1044 ETCRTINGIHSNISVSYLEGCYPRCPKDRPIYE-EDLKKCVTADKCGCYVEDTHYPPGAS 1102

Query: 371  -VTIAACQTCRCT 382
              T   C++C CT
Sbjct: 1103 VPTEETCKSCVCT 1115



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 85/298 (28%), Positives = 129/298 (43%), Gaps = 33/298 (11%)

Query: 834  VSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYI 893
            +S  GG+EL T+ RT +            H  + C+ +G  H  TFDG  F F G C+Y 
Sbjct: 15   LSLAGGSELQTEGRTRN------------HGHNVCSTWGNFHYKTFDGDVFRFPGLCDYN 62

Query: 894  LATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLS--VVLADRNYTVTGEEP 951
             A+D  G      ++K    ++  G         ++  L  +    +   R+  V     
Sbjct: 63   FASDCRG------SYKEFAVHLKRGPGQAEAPAGVESILLTIKDDTIYLTRHLAVLNGAV 116

Query: 952  HVQLGVTPGALSLVVDI--SIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNM 1009
                  +PG L    D    +  R  LTL+WNR   +++ +    ++  CGLCG++NG +
Sbjct: 117  VSTPHYSPGLLIEKSDAYTKVYSRAGLTLMWNREDALMLELDTKFRNHTCGLCGDYNG-L 175

Query: 1010 KDDFETRSRYVASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINS 1066
            +   E  S  V  S LE  N  K      +C D      P S +   R+  ER   ++ +
Sbjct: 176  QSYSEFLSDGVLFSPLEFGNMQKINQPDVVCEDPEEEVAPASCSE-HRAECER---LLTA 231

Query: 1067 QTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRT 1123
            + FA C   V   PY  AC +D C C  GGD  C+C  VA +++ C   G    +WRT
Sbjct: 232  EAFADCQDLVPLEPYLRACQQDRCRC-PGGD-TCVCSTVAEFSRQCSHAGGRPGNWRT 287



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 115/491 (23%), Positives = 180/491 (36%), Gaps = 74/491 (15%)

Query: 770  FKSCSQSSENKF-GAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCV---PPE 825
            F +CS S   +F   +C  T     T     PT  +P    ++        +C    PP 
Sbjct: 1820 FVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPR 1879

Query: 826  E-------CPCEFSGVSYPGGAEL-HTDCRTC---SCSRGRW--------ACQQGTHCPS 866
            +       C C  +   Y    E+   +C      +CS G           C     C  
Sbjct: 1880 QENETWWLCDCFMATCKYNNTVEIVKVECEPPPMPTCSNGLQPVRVEDPDGCCWHWECDC 1939

Query: 867  TCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTCS 925
             CT +G+ H +TFDG  + + GNC Y+L  +   ++ S   F +  +N  C  N  V+C 
Sbjct: 1940 YCTGWGDPHYVTFDGLYYSYQGNCTYVLVEE---ISPSVDNFGVYIDNYHCDPNDKVSCP 1996

Query: 926  RAI------------KIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVDISIPGR 973
            R +             + +  + V +      V        L V    ++ VVDI   G 
Sbjct: 1997 RTLIVRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEVYQSGINYVVDIPELG- 2055

Query: 974  YNLTLIWNRHMTILIRIA-RASQDPLCGLCGNFNGNMKDDF-----ETRSRYVASSELEL 1027
                L+    ++  +R+      +   G CG       DD      E  S   A+++  L
Sbjct: 2056 ---VLVSYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWL 2112

Query: 1028 VNSWKESPLCGDVSFVTDPCSLNA--------FRRSWAERKCSVINSQTFATCHSKVYHL 1079
            VN     P C   S  T   ++           +       C +I    FA CH+ V   
Sbjct: 2113 VND-PSKPHCPHSSSTTKRPAVTVPGGGKTTPHKDCTPSPLCQLIKDSLFAQCHALVPPQ 2171

Query: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWR--TPAFCPIYCGFYNTH 1137
             YY+ACV D+C    G   EC   ++ AYA  C  + +C+DWR  T   C + C  +  +
Sbjct: 2172 HYYDACVFDSCFM-PGSSLECA--SLQAYAALCAQQNICLDWRNHTHGACLVECPSHREY 2228

Query: 1138 TQDGHGE----YQYTQEANCTWHYQPCLCPSQPQS-VPGSN--IEGCYNCSQD----EYF 1186
               G  E       + + N T   + C CP    +  PG +  ++ C     D    E+ 
Sbjct: 2229 QACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGTMNYAPGFDVCVKTCGCVGPDNVPREFG 2288

Query: 1187 DHEEGVCVPCM 1197
            +H E  C  C+
Sbjct: 2289 EHFEFDCKNCV 2299



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 82/311 (26%), Positives = 135/311 (43%), Gaps = 42/311 (13%)

Query: 105 VVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLV 164
           VV  S+  + + ++ V +LP+ +    +        +V+  + + L+V   P   L V +
Sbjct: 359 VVFKSDGSVLLNELQV-NLPHVTASFSVFRPSSYHIMVSMAIGVRLQVQLAPVMQLFVTL 417

Query: 165 ERKYMGQMCGLCGNFDGKVTNEFVSEEG-------KFLEPHKFAA-----LQKLDDPGEI 212
           ++   GQ+ GLCGNF+G   ++F +  G        F    K  +     L  LDDP   
Sbjct: 418 DQASQGQVQGLCGNFNGLEGDDFKTASGLVEATGAGFANTWKAQSSCHDKLDWLDDP--- 474

Query: 213 CTFQDIPSTHVRQAQHA-RICTQLLTLVAP--ECSVSKEP--FVLSCQADVAAAPQPGPQ 267
           C      S ++  A +A   C+ L     P   C  + +P  +   C+ D         +
Sbjct: 475 C------SLNIESANYAEHWCSLLKKTETPFGRCHSAVDPAEYYKRCKYDTCNC--QNNE 526

Query: 268 NSSCATLSEYSRQCSMVGQPVRRWRSPGLCS--VGQCPANQVYQECGSACVKTCSNPQHS 325
           +  CA LS Y+R C+  G  +  WR   +C+  VG CP +QV+    + C +TC +   +
Sbjct: 527 DCLCAALSSYARACTAKGVMLWGWRE-HVCNKDVGSCPNSQVFLYNLTTCQQTCRSLSEA 585

Query: 326 CSSSC------TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC 379
             S C        GC CP+ T L++      CVP+ +C C   G     G+V +   + C
Sbjct: 586 -DSHCLEGFAPVDGCGCPDHTFLDEKGR---CVPLAKCSCYHRGLYLEAGDVVVRQEERC 641

Query: 380 RCTLGRWVCTE 390
            C  GR  C +
Sbjct: 642 VCRDGRLHCRQ 652



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 104/409 (25%), Positives = 162/409 (39%), Gaps = 64/409 (15%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRR---GPDGSIS---RII 98
            C+ WG  H+ TFD   Y + G C Y+       +   F V +      P+  +S    +I
Sbjct: 1941 CTGWGDPHYVTFDGLYYSYQGNCTYVLVEEISPSVDNFGVYIDNYHCDPNDKVSCPRTLI 2000

Query: 99   VELGASVVTVSEAIISVKDIGV------ISLPYTSNGLQITPFGQSVRLVAKQLELELEV 152
            V      V +    +    + V      ++LPY   GL++  +   +  V    EL + V
Sbjct: 2001 VRHETQEVLIKTVHMMPMQVQVQVNRQAVALPYKKYGLEV--YQSGINYVVDIPELGVLV 2058

Query: 153  VWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKL-DDPGE 211
             +   S  + L   ++     G CG      +++ +   G+ +   + AA Q L +DP +
Sbjct: 2059 SYNGLSFSVRLPYHRFGNNTKGQCGTCTNTTSDDCILPSGEIVSNCEAAADQWLVNDPSK 2118

Query: 212  -ICTFQDIPSTHVRQAQHA---------RICTQLLTLVAPECSVSKEPFVLSCQADVA-- 259
              C      ST  R A            + CT      +P C + K+     C A V   
Sbjct: 2119 PHCPHSS--STTKRPAVTVPGGGKTTPHKDCTP-----SPLCQLIKDSLFAQCHALVPPQ 2171

Query: 260  ---------AAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWR--SPGLCSVGQCPANQVY 308
                     +   PG  +  CA+L  Y+  C+     +  WR  + G C V +CP+++ Y
Sbjct: 2172 HYYDACVFDSCFMPG-SSLECASLQAYAALCAQQNICL-DWRNHTHGACLV-ECPSHREY 2228

Query: 309  QECGSACVKTC-SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
            Q CG A   TC S+     ++    GCFCPEGT +N       CV    C CV  G    
Sbjct: 2229 QACGPAEEPTCKSSSSQQNNTVLVEGCFCPEGT-MNYAPGFDVCVKT--CGCV--GPDNV 2283

Query: 368  P---GEVTIAACQTCRCTLG--RWVCTERPCP----GHCSLEGGSFVTT 407
            P   GE     C+ C C  G    +C  + C      HC +E G+++ T
Sbjct: 2284 PREFGEHFEFDCKNCVCLEGGSGIICQPKRCSQKPVTHC-VEDGTYLAT 2331



 Score = 72.4 bits (176), Expect = 5e-12
 Identities = 76/325 (23%), Positives = 124/325 (38%), Gaps = 31/325 (9%)

Query: 395 GH--CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGAL--MAVYDKSGVSHSETS 450
           GH  CS  G     TFD   +RF G C Y      +    G+    AV+ K G   +E  
Sbjct: 33  GHNVCSTWGNFHYKTFDGDVFRFPGLCDYNFASDCR----GSYKEFAVHLKRGPGQAEAP 88

Query: 451 L-VAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVV 509
             V  + L+ +D  +     +   NG     P+ +  + +  ++  + ++ +  GL L+ 
Sbjct: 89  AGVESILLTIKDDTIYLTRHLAVLNGAVVSTPHYSPGLLI-EKSDAYTKVYSRAGLTLMW 147

Query: 510 QLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPA 569
                    + +  +FR  T GLCG++NG  +     S G+    + L   + +  N P 
Sbjct: 148 NREDALM--LELDTKFRNHTCGLCGDYNGLQSYSEFLSDGVL--FSPLEFGNMQKINQPD 203

Query: 570 AL----ERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNY 625
            +    E E  P S S+    C        L T   F  C   V   P+ + C    C  
Sbjct: 204 VVCEDPEEEVAPASCSEHRAECER------LLTAEAFADCQDLVPLEPYLRACQQDRCRC 257

Query: 626 EETFPHICAALGDYVHACSLRGVLLWGWRSSVD----NCTIPCTGNTTFSYNSQACERTC 681
                 +C+ + ++   CS  G     WR++        +  C GN  +  +   C  TC
Sbjct: 258 PGGDTCVCSTVAEFSRQCSHAGGRPGNWRTATSAVSPGASKTCPGNLVYLESGSPCMDTC 317

Query: 682 LSLSDRATECHHSAVPVDGCNCPDG 706
             L   +    H    +DGC CP+G
Sbjct: 318 SHLEVSSLCEEHR---MDGCFCPEG 339



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 77/308 (25%), Positives = 104/308 (33%), Gaps = 96/308 (31%)

Query: 1195 PCMPPTTPQPPTTPQLPTT----------GSRPTQVWPMTGTSTTIGLLSSTGPS----- 1239
            P   PT  Q PTT  + TT           ++ T V P+T T+T     + TG       
Sbjct: 1577 PTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMI 1636

Query: 1240 PSSNHTPASPTQTPLL----PATLTSSKPTA---SSGEPPRPTTAVTPQATSG------- 1285
            P S  T  +PT TP      P T TS+ P A   +S  PP  +T  T ++TS        
Sbjct: 1637 PISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTT 1696

Query: 1286 ----LPPTATLRSTATKPTVTQATTRATASTASPAT-------------TSTAQSTTRTT 1328
                LPP   + STA   T T  TT +   T SP               T+T  S+  T 
Sbjct: 1697 LLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTP 1756

Query: 1329 MTLPTPATSGTSPT-LPKST-----------------------------NQELPGTTATQ 1358
             T+ T  TS  +PT  P ST                              +E+   T   
Sbjct: 1757 STVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGD 1816

Query: 1359 T--------------------TGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYT 1398
            T                    + P PTP  +    TP     T    T  T+     ++ 
Sbjct: 1817 TCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFD 1876

Query: 1399 TPQTPHTT 1406
             P+  + T
Sbjct: 1877 PPRQENET 1884



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 4/99 (4%)

Query: 2340 TPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVDARCSCCRPL 2399
            TP   +   CS      E+++ GC   V +  C G+C +   ++   Q +D  CSCC+  
Sbjct: 2526 TPRNETRVPCSTVPVTTEVSYAGCTKTVLMNHCSGSCGTFVMYSAKAQALDHSCSCCKEE 2585

Query: 2400 HSYEQQLELPCPDPSTPGRRLVLTLQVFSHCVCSSVACG 2438
             + ++++ L CP+    G  L  T      C C    CG
Sbjct: 2586 KTSQREVVLSCPN----GGSLTHTYTHIESCQCQDTVCG 2620


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
            sapiens]
          Length = 2134

 Score =  658 bits (1698), Expect = 0.0
 Identities = 441/1412 (31%), Positives = 625/1412 (44%), Gaps = 122/1412 (8%)

Query: 263  QPGPQNSSCATLSEYSRQCSMVGQPV-RRWRSPG--LCSVGQCPANQVYQECGSACVKTC 319
            Q   + S+C T SE SR C+  G      WRS    +C   +CP   +Y+ECG +   TC
Sbjct: 720  QTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATC 779

Query: 320  SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQT- 378
            SN      S C  GC CPEG +L+D+     CV   +CPC   G +Y PGEV    C + 
Sbjct: 780  SNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQ 839

Query: 379  CRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAV 438
            C C   +W CTE  CPG C +EG S +TTFD   Y F G C ++ + +    ED ++   
Sbjct: 840  CTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHN----EDWSISVE 894

Query: 439  YDKSGVSHSETSLVAVVYLSRQ----DKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTS 494
                    + T L +V  L       DK V + D  VTN+       Y +  I +F  +S
Sbjct: 895  LRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASS 954

Query: 495  THLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGT 554
            ++LQ+ T F ++L +Q+ P+ Q YV++ P     T GLCG++N    DDF +S  I E T
Sbjct: 955  SYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKT 1014

Query: 555  ASLFVDSWRAGNCPAALERETDPCSMSQLNKV-CAETHCSMLLRTGTVFERCHATVNPAP 613
            +  F +SW   +CP       +P S   + K   AE HC +LL +      CH  VNP P
Sbjct: 1015 SQAFANSWEMMSCPKG-----NPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKP 1069

Query: 614  FYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYN 673
            +++ C    C  E +   +C  LG+YV AC+ +   + GWR+ +  C   C     F YN
Sbjct: 1070 YHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYN 1127

Query: 674  SQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILA 733
             +AC  +C SLS+R   C    VPVDGC CPD  Y N +G CV K+QC C +   + +  
Sbjct: 1128 VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIND-EVMQP 1186

Query: 734  EQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLA 793
             +   I+   C C +G L C     + L +C     +  CS     +       TC    
Sbjct: 1187 GKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQR---RTNRTCSTRN 1243

Query: 794  TGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSR 853
              V      C+ GC C EG+  N+ G CV P +CPC F G  Y  G+     C  C+C +
Sbjct: 1244 IPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIK 1303

Query: 854  GRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTE 913
            G W+C Q   C + C +YGEGHV TFDG+ + FDG C+Y    D CG  +   TF+ILTE
Sbjct: 1304 GSWSCTQN-ECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENG--TFRILTE 1360

Query: 914  NVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLV---VDISI 970
            +V C   G+TCSR I +     ++VL D   T        +  +   A S+    + + +
Sbjct: 1361 SVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLIL 1420

Query: 971  PGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNS 1030
              +  + +IW+++  + + +       +CGLCGN NG++KDDF TR   VAS  LE  NS
Sbjct: 1421 KFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS 1480

Query: 1031 WKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDAC 1090
            WK S  C D    T PC  N + ++WA RKC ++   TF  CH+KV    Y++ C+ +AC
Sbjct: 1481 WKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEAC 1540

Query: 1091 GCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQE 1150
             CD  G     C AVA YA+AC   GVCV WR P  CP+YC +YN               
Sbjct: 1541 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNA-------------P 1587

Query: 1151 ANCTWHYQPC------LCPSQPQSVPGSN-IEGCYNCSQDE--YFDHEEGVCVPCMPPTT 1201
              C WHY+PC       C  Q      S+ +EGCY    D   Y D     CV     + 
Sbjct: 1588 GECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSC 1647

Query: 1202 PQPPTTP------------------QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSN 1243
                  P                  QL  + + PT       T+T   +LS+     +  
Sbjct: 1648 FYNDVIPAGGVIEDNCGRTCYCIAGQLECSETAPTNSTFAVSTTTATTILST---GAAIT 1704

Query: 1244 HTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRST----ATKP 1299
                 P+    +PA  TSS  T  +   P      T    + +P  +T  +        P
Sbjct: 1705 LVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSP 1764

Query: 1300 TVTQATTRA-TASTASPATTSTAQSTTRTTMTLP-------------TPATSGTSPTLPK 1345
            TVT A+  A T      ATT  A   T      P             TP  +G   T+  
Sbjct: 1765 TVTGASGMAGTTGGVDAATTGAASENTSERAGTPRVSGATPAVGGGSTPGEAGPGATVSG 1824

Query: 1346 STNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHT 1405
            ST       TA+       + +S +G T P  G  T  T++E     T++E  +  T  +
Sbjct: 1825 STGVSAGSITASPGASATSSESSKSGTTGPSVGGKTGATSSEA----TSSEGMSGVTGQS 1880

Query: 1406 THSPPTAGSPVPSTGPVTATSFHATTTYPTPSHP----------ETTLPTHVPPFSTSLV 1455
              S   + S + +    T +S     T P+P  P               T     +TS  
Sbjct: 1881 LGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGA 1940

Query: 1456 TPSTHTVITPTHA-----QMATSASNHSAPTGTIPPPTTLKATGSTHTAP----PITPTT 1506
              ST   +  T +        TS +  + P  T    T + + G+T  AP    P     
Sbjct: 1941 LGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADI 2000

Query: 1507 SGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566
              TS   S  S + + T L+        P V+  STT+   +P S  T    A   + + 
Sbjct: 2001 GNTSFGKSGKSGHDSLTVLNP-AFLRRTPTVSAASTTS---SPVSKHTDAASATAVTISG 2056

Query: 1567 SRPPPPFTTHSPPTG---SSPFSSTGPMTATS 1595
            S+P  P T     +G   +S +SS+G  T +S
Sbjct: 2057 SKPGTPGTPGGATSGGKITSGWSSSGTSTGSS 2088



 Score =  110 bits (274), Expect = 2e-23
 Identities = 100/372 (26%), Positives = 152/372 (40%), Gaps = 36/372 (9%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAAT-CKDAFPTFSVQLRRGP---DG-SISRIIV 99
            C  +G GH  TFD   Y F G C Y F    C     TF +     P   DG + SR I+
Sbjct: 1317 CHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSRKII 1376

Query: 100  ELGASVVTVSEAIISVKDIGVISLPYT-SNGLQITPFGQSVRLVAKQLELELE----VVW 154
                  V   +  I ++D  V ++  T S   ++     S+  V   L L+ +    V+W
Sbjct: 1377 ------VAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIW 1430

Query: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLE-PHKFAALQKLDDPGEIC 213
              ++ L V+++  + G++CGLCGN +G + ++F +          +F    K        
Sbjct: 1431 DKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDT 1490

Query: 214  TFQDIP--STHVRQAQHARICTQLLTLVAPECSVSKEPFVLS--CQADVAAAPQPGPQNS 269
              Q  P  S    +A   R C  L      +C    +P      C  +  A    G    
Sbjct: 1491 VAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLG 1550

Query: 270  SCATLSEYSRQCSMVGQPVRRWRSPGLCSV--------GQCPANQVYQECGSACVKTCSN 321
             C  ++ Y+  CS VG  V  WR P LC V        G+C  +  Y+ CG+   KTC +
Sbjct: 1551 FCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKTCKD 1607

Query: 322  PQHSCS-SSCTFGCF--CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQT 378
                   SS   GC+  CP+     D  N   CV +++C C  +  + A G +     +T
Sbjct: 1608 QLVGQKFSSLLEGCYAKCPDSAPYLD-ENTMKCVSLSECSCFYNDVIPAGGVIEDNCGRT 1666

Query: 379  CRCTLGRWVCTE 390
            C C  G+  C+E
Sbjct: 1667 CYCIAGQLECSE 1678



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 98/402 (24%), Positives = 164/402 (40%), Gaps = 54/402 (13%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGS----ISRII 98
            G+C   G+   +TFD   Y+F G C+++ A   +D   + SV+LR  P G     ++ + 
Sbjct: 856  GRCKVEGSS-LTTFDGVKYNFPGNCHFL-AVHNEDW--SISVELRPCPSGQTGTCLNSVT 911

Query: 99   VELGASV-----VTVSEAIIS---VKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELEL 150
            + L +SV     V  S+  ++   +++ G     Y S+ +QI     S   V     ++L
Sbjct: 912  LLLNSSVPVDKYVFNSDGTVTNDKIRNQGY----YYSDKIQIFNASSSYLQVETYFHVKL 967

Query: 151  EVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG 210
            ++   P   L V +         GLCG+++ K  ++F+S +   LE    A     +   
Sbjct: 968  QIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ-NILEKTSQAFANSWE--- 1023

Query: 211  EICTFQDIPSTHV---RQAQHARICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQ 263
             +   +  PS+ +   ++    R C  LL    P  S    V+ +P+   C+        
Sbjct: 1024 MMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC-- 1081

Query: 264  PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTC---S 320
               Q+  C  L  Y + C+     +  WR+ GLC    CP+  V++    AC  +C   S
Sbjct: 1082 ENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCE-HSCPSGLVFKYNVKACNSSCRSLS 1139

Query: 321  NPQHSC--SSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQT 378
                SC        GC CP+    N   N   CV  +QC C ++  +  PG++       
Sbjct: 1140 ERDRSCDVEDVPVDGCTCPDAMYQN---NEGNCVLKSQCDCYINDEVMQPGKLIHIDDNK 1196

Query: 379  CRCTLGRWVC------TERPCPGHCSLEGGSFVTTFDARPYR 414
            C C  G  +C      T + C G     G  +V   D +  R
Sbjct: 1197 CVCRDGILLCQIPIDLTLQNCSG-----GAEYVDCSDPKAQR 1233



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 120/457 (26%), Positives = 177/457 (38%), Gaps = 53/457 (11%)

Query: 1751 SHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
            S T+ T+     ST+T +      STG    +     +T++ +P   T+ S  TGTT   
Sbjct: 1677 SETAPTNSTFAVSTTTATTI---LSTGAAITLVTGGPSTAASIPAITTSSSETTGTT--- 1730

Query: 1811 STGPVTATSFQTTTTYPTPSHPHTT--LPTHVPSFSTSLVTPSTHTVIIPTHT----QMA 1864
              GP+T               P TT    T VP  STS     T  V+ PT T       
Sbjct: 1731 -LGPLT--------------EPFTTGITETSVPIISTSGNAGMT-GVVSPTVTGASGMAG 1774

Query: 1865 TSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSS 1924
            T+  + +  TG     T+ +A   T      TP   G S    +   A  S S      S
Sbjct: 1775 TTGGVDAATTGAASENTSERA--GTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGS 1832

Query: 1925 -THHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGP 1983
             T  P  + TS+     + + +GT  P     + ++S   T     S  TG S  S+ G 
Sbjct: 1833 ITASPGASATSS-----ESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGS 1887

Query: 1984 MTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPT 2043
             +  + +T+ T  +P   + T P+   P   S  T     V  T      TS ++ ST  
Sbjct: 1888 DSEITAKTSFTGSSPP-GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGST-E 1945

Query: 2044 GTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPP 2103
            G+V   T   + GS +TA      TSGT  T    +TA + +  +S  +      SS P 
Sbjct: 1946 GSVEATT---SAGSGNTA-----GTSGTGDTGPG-NTAVSGTPVVSPGATPGAPGSSTPG 1996

Query: 2104 SSPI--TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT 2161
             + I  T+      S    ++  N      +P+ SA ST SS  P S  +   S+ +V  
Sbjct: 1997 EADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSS--PVSKHTDAASATAVTI 2054

Query: 2162 SSSFVSAPVHSTTLSSGSH--SSLSTHPTTASVSASP 2196
            S S    P      +SG    S  S+  T+   S +P
Sbjct: 2055 SGSKPGTPGTPGGATSGGKITSGWSSSGTSTGSSNTP 2091



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 117/479 (24%), Positives = 181/479 (37%), Gaps = 113/479 (23%)

Query: 1844 STSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTS 1903
            S +  T ST  V   T T + ++ +  ++ TG   P T       T ++   T TT G  
Sbjct: 1677 SETAPTNSTFAVSTTTATTILSTGAAITLVTGG--PSTAASIPAITTSSSETTGTTLGPL 1734

Query: 1904 QSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPV-AHTTSASSS-- 1960
              P  F+T  T TS+P   S++ +  +T   +  +T      GT   V A TT A+S   
Sbjct: 1735 TEP--FTTGITETSVPI-ISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENT 1791

Query: 1961 --RLPTPFTTHSPPT---GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTS 2015
              R  TP  + + P    GS+P    GP    S  T                     S  
Sbjct: 1792 SERAGTPRVSGATPAVGGGSTP-GEAGPGATVSGSTGV-------------------SAG 1831

Query: 2016 LVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTS--- 2072
             +T S            A++ S  S+ +GT  P    K TG+T +    +   SG +   
Sbjct: 1832 SITASPG----------ASATSSESSKSGTTGPSVGGK-TGATSSEATSSEGMSGVTGQS 1880

Query: 2073 --QTHSSFSTATASSSFISSSSWLPQNSSSRP-PSSPITTQLPHLSSATTPVSTTNQLSS 2129
               T  S S  TA +SF  SS   P    +RP P SP      H S  TT          
Sbjct: 1881 LGSTAGSDSEITAKTSFTGSS---PPGKLTRPSPGSP-----GHFSGGTTEWGN------ 1926

Query: 2130 SFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLS----T 2185
                           V ++ ++ + +S ++G++   V A   +T+  SG+ +  S    T
Sbjct: 1927 ---------------VATTGAAGENTSGALGSTEGSVEA---TTSAGSGNTAGTSGTGDT 1968

Query: 2186 HPTTASVSASPLF-----PSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSH 2240
             P   +VS +P+      P +P +ST   A + +T                +   +  S 
Sbjct: 1969 GPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNT----------------SFGKSGKSG 2012

Query: 2241 LASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSP 2299
              S T+  P+  R T      P  S+ STTS   S  T   ++  V+++    G P +P
Sbjct: 2013 HDSLTVLNPAFLRRT------PTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 2065



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 105/435 (24%), Positives = 157/435 (36%), Gaps = 58/435 (13%)

Query: 1649 PTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            PT +    +T  AT    T   +TL T G S A S        T+  S T+ T     T 
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTGGPSTAAS----IPAITTSSSETTGTTLGPLTE 1736

Query: 1709 TSTTNITP------------------NPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLH 1750
              TT IT                   +PT TG   M  TT G   + +  ++  TS    
Sbjct: 1737 PFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAG 1796

Query: 1751 SHTSSTHHPEVTSTSTT-SITPNHTSTG---------TRTPVAHTTSATSSRLPTPFTTH 1800
            +   S   P V   ST     P  T +G         T +P A  TS+ SS+  T   + 
Sbjct: 1797 TPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGPSV 1856

Query: 1801 SPPTGTTPISSTGP-----VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTV 1855
               TG T   +T       VT  S  +T    +     T+     P    +  +P +   
Sbjct: 1857 GGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGS--- 1913

Query: 1856 IIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
              P H    T+   +   TG     T+  A GST  +   T T++G+  +  +  T  T 
Sbjct: 1914 --PGHFSGGTTEWGNVATTGAAGENTS-GALGSTEGSVEAT-TSAGSGNTAGTSGTGDTG 1969

Query: 1916 TSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGS 1975
               P +T+ +  P V+P +T       +ST     + +T+   S +     + H   T  
Sbjct: 1970 ---PGNTAVSGTPVVSPGATPG--APGSSTPGEADIGNTSFGKSGK-----SGHDSLTVL 2019

Query: 1976 SP-FSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMAT 2034
            +P F    P    S  +TT+ P   H      T V    +   TP T     T+  ++ +
Sbjct: 2020 NPAFLRRTP--TVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGG-ATSGGKITS 2076

Query: 2035 SASIHSTPTGTVPPP 2049
              S   T TG+   P
Sbjct: 2077 GWSSSGTSTGSSNTP 2091



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 89/376 (23%), Positives = 138/376 (36%), Gaps = 54/376 (14%)

Query: 2010 PPFSTSLVTPSTHTVIITTHTQM-------ATSASIHSTPTG-------TVPPPTTLKAT 2055
            P  ST  V+ +T T I++T   +       +T+ASI +  T        T+ P T    T
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTT 1740

Query: 2056 GSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLP--------QNSSSRPPSSPI 2107
            G T T+ P+  T+     T     T T +S    ++  +         +N+S R  +  +
Sbjct: 1741 GITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAGTPRV 1800

Query: 2108 TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVS 2167
            +   P +   +TP       + S S   SA S  +S   S+ SS  + S + G S     
Sbjct: 1801 SGATPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGPSVGG-- 1858

Query: 2168 APVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLP 2227
                     +G+ SS +T     S        S+  + + I A    T SSP       P
Sbjct: 1859 --------KTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSP-------P 1903

Query: 2228 ISTVTVSPTPSSHLASSTIAFPSTPRT-TASTHTAPAFSS-----QSTTSRSTSLTTRVP 2281
                  SP    H +  T  + +   T  A  +T+ A  S     ++TTS  +  T    
Sbjct: 1904 GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNT--AG 1961

Query: 2282 TSGFVSLTSGVTGIPTSPVTN-------LTTRHPGPTLSPTTRFLTSSLTAHGSTPASAP 2334
            TSG      G T +  +PV +         +  PG      T F  S  + H S     P
Sbjct: 1962 TSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNP 2021

Query: 2335 VSSLGTPTPTSPGVCS 2350
                 TPT ++    S
Sbjct: 2022 AFLRRTPTVSAASTTS 2037



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 113/421 (26%), Positives = 166/421 (39%), Gaps = 62/421 (14%)

Query: 1617 PPFSTSLVTPSTHTVITPTHAQM-------ATSASI------HSMPTGTIPPPTTLK-AT 1662
            P  ST  V+ +T T I  T A +       +T+ASI       S  TGT   P T    T
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTT 1740

Query: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITP---NPT 1719
            G T T+  + ++TSG +     ++   T  S  + T+    A  T  ++ N +     P 
Sbjct: 1741 GITETSVPI-ISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAGTPR 1799

Query: 1720 STGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT--STG 1777
             +G  P  V    T       +T   ST + S  S T  P  ++TS+ S     T  S G
Sbjct: 1800 VSGATP-AVGGGSTPGEAGPGATVSGSTGV-SAGSITASPGASATSSESSKSGTTGPSVG 1857

Query: 1778 TRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTT-----TYPTPSHP 1832
             +T  A ++ ATSS   +  T  S   G+T  S +     TSF  ++     T P+P  P
Sbjct: 1858 GKTG-ATSSEATSSEGMSGVTGQS--LGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSP 1914

Query: 1833 ----------HTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTT 1882
                           T     +TS    ST   +  T T   +  +  +  TG   P  T
Sbjct: 1915 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEAT-TSAGSGNTAGTSGTGDTGPGNT 1973

Query: 1883 IKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS---TSLPYHTSST--------HHPEVT 1931
               +G+   +P  TP   G+S +P       TS   +    H S T          P V+
Sbjct: 1974 -AVSGTPVVSPGATPGAPGSS-TPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVS 2031

Query: 1932 PTSTTNI-TPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTG---SSPFSSTGPMTAT 1987
              STT+    KHT   + T V    + S S+  TP T     +G   +S +SS+G  T +
Sbjct: 2032 AASTTSSPVSKHTDAASATAV----TISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGS 2087

Query: 1988 S 1988
            S
Sbjct: 2088 S 2088



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 43  GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPD 91
           G+ STW  G + +F+  ++ F  +C Y F   C ++   F+++++R  D
Sbjct: 606 GEISTWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNND 654


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
            sapiens]
          Length = 2134

 Score =  658 bits (1697), Expect = 0.0
 Identities = 441/1412 (31%), Positives = 624/1412 (44%), Gaps = 122/1412 (8%)

Query: 263  QPGPQNSSCATLSEYSRQCSMVGQPV-RRWRSPG--LCSVGQCPANQVYQECGSACVKTC 319
            Q   + S+C T SE SR C+  G      WRS    +C   +CP   +Y+ECG +   TC
Sbjct: 720  QTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCGTQRCPEQHIYKECGPSNPATC 779

Query: 320  SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQT- 378
            SN      S C  GC CPEG +L+D+     CV   +CPC   G +Y PGEV    C + 
Sbjct: 780  SNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQ 839

Query: 379  CRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAV 438
            C C   +W CTE  CPG C +EG S +TTFD   Y F G C ++ + +    ED ++   
Sbjct: 840  CTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHN----EDWSISVE 894

Query: 439  YDKSGVSHSETSLVAVVYLSRQ----DKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTS 494
                    + T L +V  L       DK V + D  VTN+       Y +  I +F  +S
Sbjct: 895  LRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASS 954

Query: 495  THLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGT 554
            ++LQ+ T F ++L +Q+ P+ Q YV++ P     T GLCG++N    DDF +S  I E T
Sbjct: 955  SYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKT 1014

Query: 555  ASLFVDSWRAGNCPAALERETDPCSMSQLNKV-CAETHCSMLLRTGTVFERCHATVNPAP 613
            +  F +SW   +CP       +P S   + K   AE HC +LL +      CH  VNP P
Sbjct: 1015 SQAFANSWEMMSCPKG-----NPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKP 1069

Query: 614  FYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYN 673
            +++ C    C  E +   +C  LG+YV AC+ +   + GWR+ +  C   C     F YN
Sbjct: 1070 YHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYN 1127

Query: 674  SQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILA 733
             +AC  +C SLS+R   C    VPVDGC CPD  Y N +G CV K+QC C +   + +  
Sbjct: 1128 VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYIND-EVMQP 1186

Query: 734  EQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLA 793
             +   I+   C C +G L C     + L +C     +  CS     +       TC    
Sbjct: 1187 GKLIHIDDNKCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQR---RTNRTCSTRN 1243

Query: 794  TGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSR 853
              V      C+ GC C EG+  N+ G CV P +CPC F G  Y  G+     C  C+C +
Sbjct: 1244 IPVFDENLPCKRGCFCPEGMVRNSKGICVFPNDCPCSFGGREYDEGSVTSVGCNECTCIK 1303

Query: 854  GRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTE 913
            G W+C Q   C + C +YGEGHV TFDG+ + FDG C+Y    D CG  +   TF+ILTE
Sbjct: 1304 GSWSCTQN-ECQTICHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENG--TFRILTE 1360

Query: 914  NVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLV---VDISI 970
            +V C   G+TCSR I +     ++VL D   T        +  +   A S+    + + +
Sbjct: 1361 SVPCCEDGLTCSRKIIVAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLIL 1420

Query: 971  PGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNS 1030
              +  + +IW+++  + + +       +CGLCGN NG++KDDF TR   VAS  LE  NS
Sbjct: 1421 KFQNGIIVIWDKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNS 1480

Query: 1031 WKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDAC 1090
            WK S  C D    T PC  N + ++WA RKC ++   TF  CH+KV    Y++ C+ +AC
Sbjct: 1481 WKTSQECSDTVAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEAC 1540

Query: 1091 GCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQE 1150
             CD  G     C AVA YA+AC   GVCV WR P  CP+YC +YN               
Sbjct: 1541 ACDMEGKYLGFCTAVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNA-------------P 1587

Query: 1151 ANCTWHYQPC------LCPSQPQSVPGSN-IEGCYNCSQDE--YFDHEEGVCVPCMPPTT 1201
              C WHY+PC       C  Q      S+ +EGCY    D   Y D     CV     + 
Sbjct: 1588 GECRWHYEPCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSC 1647

Query: 1202 PQPPTTP------------------QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSN 1243
                  P                  QL  + + PT       T+T   +LS+     +  
Sbjct: 1648 FYNDVIPAGGVIEDNCGRTCYCIAGQLECSETAPTNSTFAVSTTTATTILST---GAAIT 1704

Query: 1244 HTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRST----ATKP 1299
                 P+    +PA  TSS  T  +   P      T    + +P  +T  +        P
Sbjct: 1705 LVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSP 1764

Query: 1300 TVTQATTRA-TASTASPATTSTAQSTTRTTMTLP-------------TPATSGTSPTLPK 1345
            TVT A+  A T      ATT  A   T      P             TP  +G   T+  
Sbjct: 1765 TVTGASGMAGTTGGVDAATTGAASENTSERAGTPRVSGETPAVGGGSTPGEAGPGATVSG 1824

Query: 1346 STNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHT 1405
            ST       TA+       + +S +G T P  G  T  T++E     T++E  +  T  +
Sbjct: 1825 STGVSAGSITASPGASATSSESSKSGTTGPSVGGKTGATSSEA----TSSEGMSGVTGQS 1880

Query: 1406 THSPPTAGSPVPSTGPVTATSFHATTTYPTPSHP----------ETTLPTHVPPFSTSLV 1455
              S   + S + +    T +S     T P+P  P               T     +TS  
Sbjct: 1881 LGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGA 1940

Query: 1456 TPSTHTVITPTHA-----QMATSASNHSAPTGTIPPPTTLKATGSTHTAP----PITPTT 1506
              ST   +  T +        TS +  + P  T    T + + G+T  AP    P     
Sbjct: 1941 LGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADI 2000

Query: 1507 SGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566
              TS   S  S + + T L+        P V+  STT+   +P S  T    A   + + 
Sbjct: 2001 GNTSFGKSGKSGHDSLTVLNP-AFLRRTPTVSAASTTS---SPVSKHTDAASATAVTISG 2056

Query: 1567 SRPPPPFTTHSPPTG---SSPFSSTGPMTATS 1595
            S+P  P T     +G   +S +SS+G  T  S
Sbjct: 2057 SKPGTPGTPGGATSGGKITSGWSSSGTSTGAS 2088



 Score =  110 bits (274), Expect = 2e-23
 Identities = 100/372 (26%), Positives = 152/372 (40%), Gaps = 36/372 (9%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAAT-CKDAFPTFSVQLRRGP---DG-SISRIIV 99
            C  +G GH  TFD   Y F G C Y F    C     TF +     P   DG + SR I+
Sbjct: 1317 CHIYGEGHVRTFDGKSYSFDGLCQYSFLEDYCGHENGTFRILTESVPCCEDGLTCSRKII 1376

Query: 100  ELGASVVTVSEAIISVKDIGVISLPYT-SNGLQITPFGQSVRLVAKQLELELE----VVW 154
                  V   +  I ++D  V ++  T S   ++     S+  V   L L+ +    V+W
Sbjct: 1377 ------VAFQDQNIVLQDGKVTAVKSTESKKCELNANAYSIHTVGLYLILKFQNGIIVIW 1430

Query: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLE-PHKFAALQKLDDPGEIC 213
              ++ L V+++  + G++CGLCGN +G + ++F +          +F    K        
Sbjct: 1431 DKNTRLSVILDPNWNGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDT 1490

Query: 214  TFQDIP--STHVRQAQHARICTQLLTLVAPECSVSKEPFVLS--CQADVAAAPQPGPQNS 269
              Q  P  S    +A   R C  L      +C    +P      C  +  A    G    
Sbjct: 1491 VAQTFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLG 1550

Query: 270  SCATLSEYSRQCSMVGQPVRRWRSPGLCSV--------GQCPANQVYQECGSACVKTCSN 321
             C  ++ Y+  CS VG  V  WR P LC V        G+C  +  Y+ CG+   KTC +
Sbjct: 1551 FCTAVAMYAEACSAVGVCV-SWRKPNLCPVYCDYYNAPGECRWH--YEPCGTVTAKTCKD 1607

Query: 322  PQHSCS-SSCTFGCF--CPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQT 378
                   SS   GC+  CP+     D  N   CV +++C C  +  + A G +     +T
Sbjct: 1608 QLVGQKFSSLLEGCYAKCPDSAPYLD-ENTMKCVSLSECSCFYNDVIPAGGVIEDNCGRT 1666

Query: 379  CRCTLGRWVCTE 390
            C C  G+  C+E
Sbjct: 1667 CYCIAGQLECSE 1678



 Score = 75.9 bits (185), Expect = 5e-13
 Identities = 98/402 (24%), Positives = 164/402 (40%), Gaps = 54/402 (13%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGS----ISRII 98
            G+C   G+   +TFD   Y+F G C+++ A   +D   + SV+LR  P G     ++ + 
Sbjct: 856  GRCKVEGSS-LTTFDGVKYNFPGNCHFL-AVHNEDW--SISVELRPCPSGQTGTCLNSVT 911

Query: 99   VELGASV-----VTVSEAIIS---VKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELEL 150
            + L +SV     V  S+  ++   +++ G     Y S+ +QI     S   V     ++L
Sbjct: 912  LLLNSSVPVDKYVFNSDGTVTNDKIRNQGY----YYSDKIQIFNASSSYLQVETYFHVKL 967

Query: 151  EVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG 210
            ++   P   L V +         GLCG+++ K  ++F+S +   LE    A     +   
Sbjct: 968  QIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQ-NILEKTSQAFANSWE--- 1023

Query: 211  EICTFQDIPSTHV---RQAQHARICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQ 263
             +   +  PS+ +   ++    R C  LL    P  S    V+ +P+   C+        
Sbjct: 1024 MMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC-- 1081

Query: 264  PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTC---S 320
               Q+  C  L  Y + C+     +  WR+ GLC    CP+  V++    AC  +C   S
Sbjct: 1082 ENSQDCLCTILGNYVKACAEKETYIVGWRT-GLCE-HSCPSGLVFKYNVKACNSSCRSLS 1139

Query: 321  NPQHSC--SSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQT 378
                SC        GC CP+    N   N   CV  +QC C ++  +  PG++       
Sbjct: 1140 ERDRSCDVEDVPVDGCTCPDAMYQN---NEGNCVLKSQCDCYINDEVMQPGKLIHIDDNK 1196

Query: 379  CRCTLGRWVC------TERPCPGHCSLEGGSFVTTFDARPYR 414
            C C  G  +C      T + C G     G  +V   D +  R
Sbjct: 1197 CVCRDGILLCQIPIDLTLQNCSG-----GAEYVDCSDPKAQR 1233



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 120/457 (26%), Positives = 177/457 (38%), Gaps = 53/457 (11%)

Query: 1751 SHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
            S T+ T+     ST+T +      STG    +     +T++ +P   T+ S  TGTT   
Sbjct: 1677 SETAPTNSTFAVSTTTATTI---LSTGAAITLVTGGPSTAASIPAITTSSSETTGTT--- 1730

Query: 1811 STGPVTATSFQTTTTYPTPSHPHTT--LPTHVPSFSTSLVTPSTHTVIIPTHT----QMA 1864
              GP+T               P TT    T VP  STS     T  V+ PT T       
Sbjct: 1731 -LGPLT--------------EPFTTGITETSVPIISTSGNAGMT-GVVSPTVTGASGMAG 1774

Query: 1865 TSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSS 1924
            T+  + +  TG     T+ +A   T      TP   G S    +   A  S S      S
Sbjct: 1775 TTGGVDAATTGAASENTSERA--GTPRVSGETPAVGGGSTPGEAGPGATVSGSTGVSAGS 1832

Query: 1925 -THHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGP 1983
             T  P  + TS+     + + +GT  P     + ++S   T     S  TG S  S+ G 
Sbjct: 1833 ITASPGASATSS-----ESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGS 1887

Query: 1984 MTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPT 2043
             +  + +T+ T  +P   + T P+   P   S  T     V  T      TS ++ ST  
Sbjct: 1888 DSEITAKTSFTGSSPP-GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGST-E 1945

Query: 2044 GTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPP 2103
            G+V   T   + GS +TA      TSGT  T    +TA + +  +S  +      SS P 
Sbjct: 1946 GSVEATT---SAGSGNTA-----GTSGTGDTGPG-NTAVSGTPVVSPGATPGAPGSSTPG 1996

Query: 2104 SSPI--TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT 2161
             + I  T+      S    ++  N      +P+ SA ST SS  P S  +   S+ +V  
Sbjct: 1997 EADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSS--PVSKHTDAASATAVTI 2054

Query: 2162 SSSFVSAPVHSTTLSSGSH--SSLSTHPTTASVSASP 2196
            S S    P      +SG    S  S+  T+   S +P
Sbjct: 2055 SGSKPGTPGTPGGATSGGKITSGWSSSGTSTGASNTP 2091



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 117/479 (24%), Positives = 180/479 (37%), Gaps = 113/479 (23%)

Query: 1844 STSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTS 1903
            S +  T ST  V   T T + ++ +  ++ TG   P T       T ++   T TT G  
Sbjct: 1677 SETAPTNSTFAVSTTTATTILSTGAAITLVTGG--PSTAASIPAITTSSSETTGTTLGPL 1734

Query: 1904 QSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPV-AHTTSASSS-- 1960
              P  F+T  T TS+P   S++ +  +T   +  +T      GT   V A TT A+S   
Sbjct: 1735 TEP--FTTGITETSVPI-ISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENT 1791

Query: 1961 --RLPTPFTTHSPPT---GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTS 2015
              R  TP  +   P    GS+P    GP    S  T                     S  
Sbjct: 1792 SERAGTPRVSGETPAVGGGSTP-GEAGPGATVSGSTGV-------------------SAG 1831

Query: 2016 LVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTS--- 2072
             +T S            A++ S  S+ +GT  P    K TG+T +    +   SG +   
Sbjct: 1832 SITASPG----------ASATSSESSKSGTTGPSVGGK-TGATSSEATSSEGMSGVTGQS 1880

Query: 2073 --QTHSSFSTATASSSFISSSSWLPQNSSSRP-PSSPITTQLPHLSSATTPVSTTNQLSS 2129
               T  S S  TA +SF  SS   P    +RP P SP      H S  TT          
Sbjct: 1881 LGSTAGSDSEITAKTSFTGSS---PPGKLTRPSPGSP-----GHFSGGTTEWGN------ 1926

Query: 2130 SFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLS----T 2185
                           V ++ ++ + +S ++G++   V A   +T+  SG+ +  S    T
Sbjct: 1927 ---------------VATTGAAGENTSGALGSTEGSVEA---TTSAGSGNTAGTSGTGDT 1968

Query: 2186 HPTTASVSASPLF-----PSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSH 2240
             P   +VS +P+      P +P +ST   A + +T                +   +  S 
Sbjct: 1969 GPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNT----------------SFGKSGKSG 2012

Query: 2241 LASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSP 2299
              S T+  P+  R T      P  S+ STTS   S  T   ++  V+++    G P +P
Sbjct: 2013 HDSLTVLNPAFLRRT------PTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 2065



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 89/376 (23%), Positives = 139/376 (36%), Gaps = 54/376 (14%)

Query: 2010 PPFSTSLVTPSTHTVIITTHTQM-------ATSASIHSTPTG-------TVPPPTTLKAT 2055
            P  ST  V+ +T T I++T   +       +T+ASI +  T        T+ P T    T
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTT 1740

Query: 2056 GSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLP--------QNSSSRPPSSPI 2107
            G T T+ P+  T+     T     T T +S    ++  +         +N+S R  +  +
Sbjct: 1741 GITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAGTPRV 1800

Query: 2108 TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVS 2167
            + + P +   +TP       + S S   SA S  +S   S+ SS  + S + G S     
Sbjct: 1801 SGETPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGPSVGG-- 1858

Query: 2168 APVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLP 2227
                     +G+ SS +T     S        S+  + + I A    T SSP       P
Sbjct: 1859 --------KTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSP-------P 1903

Query: 2228 ISTVTVSPTPSSHLASSTIAFPSTPRT-TASTHTAPAFSS-----QSTTSRSTSLTTRVP 2281
                  SP    H +  T  + +   T  A  +T+ A  S     ++TTS  +  T    
Sbjct: 1904 GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNT--AG 1961

Query: 2282 TSGFVSLTSGVTGIPTSPVTN-------LTTRHPGPTLSPTTRFLTSSLTAHGSTPASAP 2334
            TSG      G T +  +PV +         +  PG      T F  S  + H S     P
Sbjct: 1962 TSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNP 2021

Query: 2335 VSSLGTPTPTSPGVCS 2350
                 TPT ++    S
Sbjct: 2022 AFLRRTPTVSAASTTS 2037



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 107/414 (25%), Positives = 159/414 (38%), Gaps = 57/414 (13%)

Query: 1386 TETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPT 1445
            +ET  T +T   +T  T  TT     A   + + GP TA S  A TT  + +   TTL  
Sbjct: 1677 SETAPTNSTFAVST--TTATTILSTGAAITLVTGGPSTAASIPAITTSSSET-TGTTLGP 1733

Query: 1446 HVPPFSTSLVTPSTHTVITPTHAQMA-------TSASNHSAPTGTIPPPTTLKATGSTHT 1498
               PF+T +   S   + T  +A M        T AS  +  TG +   TT  A+ +T  
Sbjct: 1734 LTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSE 1793

Query: 1499 APPITPTTSGTSQAHSSFST--NKTPTSLHSHTSSTHHPEVT--PTSTTTITPNPTSTRT 1554
                TP  SG + A    ST     P +  S ++      +T  P ++ T + +  S  T
Sbjct: 1794 RAG-TPRVSGETPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTT 1852

Query: 1555 RTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTP----SHPQT 1610
               V     ATSS         S  TG S  S+ G  +  + KT+ T  +P    + P  
Sbjct: 1853 GPSVGGKTGATSSEATSS-EGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSP 1911

Query: 1611 TLPTH---------------VPPFSTSLVTPSTHTVITPTHAQ-----MATSASIHSMPT 1650
              P H                   +TS    ST   +  T +        TS +  + P 
Sbjct: 1912 GSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPG 1971

Query: 1651 GTIPPPTTLKATGSTHTAPTMTL--------TTSGTS-----QALSSLNTA---KTST-S 1693
             T    T + + G+T  AP  +         T+ G S      +L+ LN A   +T T S
Sbjct: 1972 NTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVS 2031

Query: 1694 LHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTST 1747
              S TSS       + S T +T + +  GTP      +   +  S +S++ TST
Sbjct: 2032 AASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKITSGWSSSGTST 2085



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 99/407 (24%), Positives = 146/407 (35%), Gaps = 57/407 (14%)

Query: 1649 PTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            PT +    +T  AT    T   +TL T G S A S        T+  S T+ T     T 
Sbjct: 1681 PTNSTFAVSTTTATTILSTGAAITLVTGGPSTAAS----IPAITTSSSETTGTTLGPLTE 1736

Query: 1709 TSTTNITP------------------NPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLH 1750
              TT IT                   +PT TG   M  TT G   + +  ++  TS    
Sbjct: 1737 PFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAG 1796

Query: 1751 SHTSSTHHPEVTSTSTT-SITPNHTSTG---------TRTPVAHTTSATSSRLPTPFTTH 1800
            +   S   P V   ST     P  T +G         T +P A  TS+ SS+  T   + 
Sbjct: 1797 TPRVSGETPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGPSV 1856

Query: 1801 SPPTGTTPISSTGP-----VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTV 1855
               TG T   +T       VT  S  +T    +     T+     P    +  +P +   
Sbjct: 1857 GGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGS--- 1913

Query: 1856 IIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
              P H    T+   +   TG     T+  A GST  +   T T++G+  +  +  T  T 
Sbjct: 1914 --PGHFSGGTTEWGNVATTGAAGENTS-GALGSTEGSVEAT-TSAGSGNTAGTSGTGDTG 1969

Query: 1916 TSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGS 1975
               P +T+ +  P V+P +T       +ST     + +T+   S +     + H   T  
Sbjct: 1970 ---PGNTAVSGTPVVSPGATPG--APGSSTPGEADIGNTSFGKSGK-----SGHDSLTVL 2019

Query: 1976 SP-FSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 2021
            +P F    P    S  +TT+ P   H      T V    +   TP T
Sbjct: 2020 NPAFLRRTP--TVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGT 2064



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 43  GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPD 91
           G+ STW  G + +F+  ++ F  +C Y F   C ++   F+++++R  D
Sbjct: 606 GEISTWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNND 654


>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
          Length = 2813

 Score =  557 bits (1436), Expect = e-158
 Identities = 356/1208 (29%), Positives = 549/1208 (45%), Gaps = 107/1208 (8%)

Query: 44   QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGA 103
            +CS +G+   +TFD  +Y F+G C+Y+ A  C+    +     + G   S+S  + E   
Sbjct: 34   RCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLSVYLGEFFD 93

Query: 104  SVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVL 163
              + V+  +        +S+PY S GL +       +L  +       +      +  VL
Sbjct: 94   IHLFVNGTVTQGDQR--VSMPYASKGLYLETEAGYYKLSGEAYGFVARI--DGSGNFQVL 149

Query: 164  VERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEICTFQDIPSTH 222
            +  +Y  + CGLCGNF+    ++F+++EG    +P+ FA    L    + C     PS+ 
Sbjct: 150  LSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQWCERASPPSSS 209

Query: 223  VR------QAQHARICTQLL--TLVAPECS--VSKEPFVLSCQADVAAAPQPGPQNSSCA 272
                    Q      C QLL  T V   C   V  EPFV  C+  +      G    +C 
Sbjct: 210  CNISSGEMQKGLWEQC-QLLKSTSVFARCHPLVDPEPFVALCEKTLCECA--GGLECACP 266

Query: 273  TLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQ--HSCSSSC 330
             L EY+R C+  G  +  W     CS   CPA   Y++C S C +TC +      C   C
Sbjct: 267  ALLEYARTCAQEGMVLYGWTDHSACSP-VCPAGMEYRQCVSPCARTCQSLHINEMCQERC 325

Query: 331  TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTE 390
              GC CPEG +L++      CV  T+CPCV  G  Y PG      C TC C   +W+C+ 
Sbjct: 326  VDGCSCPEGQLLDE----GLCVESTECPCVHSGKRYPPGTSLSRDCNTCICRNSQWICSN 381

Query: 391  RPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSE-- 448
              CPG C + G S   +FD R + F G C Y+L +  Q   D +   V +    +     
Sbjct: 382  EECPGECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQ---DHSFSIVIETVQCADDRDA 438

Query: 449  --TSLVAVVYLSRQDKIV-ISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGL 505
              T  V V      + +V +     V  +G+   LP    ++ +    +  +++  S+G 
Sbjct: 439  VCTRSVTVRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRL--SYGE 496

Query: 506  ELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA- 564
            +L +      +  V + P + G+T GLCGN+NG+  DDF T  G+AE     F ++W+  
Sbjct: 497  DLQMDWDGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSGLAEPRVEDFGNAWKLH 556

Query: 565  GNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN 624
            G+C    ++ +DPC+++      +E  C++L  T   FE CH  V+P P+ + C Y  C+
Sbjct: 557  GDCQDLQKQHSDPCALNPRMTRFSEEACAVL--TSPTFEACHRAVSPLPYLRNCRYDVCS 614

Query: 625  YEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSL 684
              +    +C AL  Y  AC+ RGV +  WR     C + C     +      C  TC SL
Sbjct: 615  CSDGRECLCGALASYAAACAGRGVRV-AWREP-GRCELNCPKGQVYLQCGTPCNLTCRSL 672

Query: 685  SDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKF----ILAEQSTVIN 740
            S    EC+ + +  +GC CP G Y++++G+CV KAQCPC  +G  F    I ++  T+  
Sbjct: 673  SYPDEECNEACL--EGCFCPPGLYMDERGDCVPKAQCPCYYDGEIFQPEDIFSDHHTM-- 728

Query: 741  GITCHCINGRLSCPQR-------PQMFLAS-----------CQAPKTFKSCSQSSENKFG 782
               C+C +G + C          P   L+S           C+ P     C   +    G
Sbjct: 729  ---CYCEDGFMHCTMSGVPGSLLPDAVLSSPLSHRSKRSLSCRPPMVKLVCPADNLRAEG 785

Query: 783  AACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAEL 842
              C  TCQ     + C+   C  GC+C  G+  + + +CV  E CPC   G  Y  G  +
Sbjct: 786  LECTKTCQNY--DLECMSMGCVSGCLCPPGMVRH-ENRCVALERCPCFHQGKEYAPGETV 842

Query: 843  HTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVN 902
               C TC C   +W C     C +TC+  G  H +TFDG +++F G C+Y+L  D CG N
Sbjct: 843  KIGCNTCVCRDRKWNCTDHV-CDATCSTIGMAHYLTFDGLKYLFPGECQYVLVQDYCGSN 901

Query: 903  DSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTP 959
                TF+IL  N  C +  V C + + I + G  + L D    V     +E H ++  + 
Sbjct: 902  PG--TFRILVGNKGCSHPSVKCKKRVTILVEGGEIELFDGEVNVKRPMKDETHFEVVESG 959

Query: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
              + L++  +      L+++W+RH++I + + +  Q+ +CGLCGNF+G   +D  + +  
Sbjct: 960  RYIILLLGKA------LSVVWDRHLSISVVLKQTYQEKVCGLCGNFDGIQNNDLTSSNLQ 1013

Query: 1020 VASSELELVNSWKESPLCGDVSFV---TDP--CSLNAFRRSWAERKCSVINSQTFATCHS 1074
            V    ++  NSWK S  C D   V   + P  C  N  +++  +  C ++ S  F  C+ 
Sbjct: 1014 VEEDPVDFGNSWKVSSQCADTRKVPLDSSPATCHNNIMKQTMVDSSCRILTSDVFQDCNK 1073

Query: 1075 KVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFY 1134
             V   PY + C+ D C C+S GDC C CD +AAYA  C   G  V WRT   CP  C   
Sbjct: 1074 LVDPEPYLDVCIYDTCSCESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATLCPQSCEER 1133

Query: 1135 NTHTQDGHGEYQYTQEANCTWHYQPCLCPSQ-------PQSVPGSNIEGCY-NCSQDEYF 1186
            N   ++G+          C W Y  C    Q       P + P   +EGC+ +C   +  
Sbjct: 1134 NLR-ENGY---------ECEWRYNSCAPACQVTCQHPEPLACPVQCVEGCHAHCPPGKIL 1183

Query: 1187 DHEEGVCV 1194
            D     CV
Sbjct: 1184 DELLQTCV 1191



 Score =  151 bits (381), Expect = 9e-36
 Identities = 111/379 (29%), Positives = 168/379 (44%), Gaps = 45/379 (11%)

Query: 43  GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSISRIIV 99
           G+C   G  HF +FD+  + FSG C Y+ A  C+D   +    +VQ     D   +R + 
Sbjct: 386 GECLVTGQSHFKSFDNRYFTFSGICQYLLARDCQDHSFSIVIETVQCADDRDAVCTRSVT 445

Query: 100 ----ELGASVVTVSEAIISVKDIGVISLPYTSNGLQIT-PFGQSVRLVAKQLELELEVVW 154
                L  S+V +        D   + LP     L+I      SVRL   +   +L++ W
Sbjct: 446 VRLPGLHNSLVKLKHGAGVAMDGQDVQLPLLKGDLRIQHTVTASVRLSYGE---DLQMDW 502

Query: 155 GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICT 214
                L+V +   Y G+ CGLCGN++G   ++F++  G   EP       +++D G    
Sbjct: 503 DGRGRLLVKLSPVYAGKTCGLCGNYNGNQGDDFLTPSG-LAEP-------RVEDFGNAWK 554

Query: 215 F----QDIPSTH----------VRQAQHARICTQLLTLVAPECSVSKEPFVLSCQADVAA 260
                QD+   H           R ++ A       T  A   +VS  P++ +C+ DV +
Sbjct: 555 LHGDCQDLQKQHSDPCALNPRMTRFSEEACAVLTSPTFEACHRAVSPLPYLRNCRYDVCS 614

Query: 261 APQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKTC 319
                 +   C  L+ Y+  C+  G+ VR  WR PG C +  CP  QVY +CG+ C  TC
Sbjct: 615 CSD--GRECLCGALASYAAACA--GRGVRVAWREPGRCEL-NCPKGQVYLQCGTPCNLTC 669

Query: 320 ---SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAAC 376
              S P   C+ +C  GCFCP G  +++  +   CVP  QCPC   G ++ P ++     
Sbjct: 670 RSLSYPDEECNEACLEGCFCPPGLYMDERGD---CVPKAQCPCYYDGEIFQPEDIFSDHH 726

Query: 377 QTCRCTLGRWVCTERPCPG 395
             C C  G   CT    PG
Sbjct: 727 TMCYCEDGFMHCTMSGVPG 745



 Score =  142 bits (357), Expect = 5e-33
 Identities = 105/366 (28%), Positives = 153/366 (41%), Gaps = 18/366 (4%)

Query: 391 RPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETS 450
           R     CSL G  FV TFD   Y F G C+Y+L    Q      +    +   VS S   
Sbjct: 29  RSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGCQKRSFSIIGDFQNGKRVSLS--- 85

Query: 451 LVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQ 510
               VYL     I +  +  VT   +   +PY ++ + +  +   +     ++G    + 
Sbjct: 86  ----VYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLSGEAYGFVARID 141

Query: 511 LRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAA 570
               FQ  V +  ++  +T GLCGNFN    DDF T  G        F +SW   +    
Sbjct: 142 GSGNFQ--VLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANSWALSSGEQW 199

Query: 571 LERETDP---CSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEE 627
            ER + P   C++S             LL++ +VF RCH  V+P PF   C    C    
Sbjct: 200 CERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALCEKTLCECAG 259

Query: 628 TFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDR 687
                C AL +Y   C+  G++L+GW +    C+  C     +      C RTC SL   
Sbjct: 260 GLECACPALLEYARTCAQEGMVLYGW-TDHSACSPVCPAGMEYRQCVSPCARTCQSLHIN 318

Query: 688 ATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCI 747
              C      VDGC+CP+G  L++ G CV   +CPC+  G ++     S   +  TC C 
Sbjct: 319 EM-CQERC--VDGCSCPEGQLLDE-GLCVESTECPCVHSGKRY-PPGTSLSRDCNTCICR 373

Query: 748 NGRLSC 753
           N +  C
Sbjct: 374 NSQWIC 379



 Score =  112 bits (280), Expect = 4e-24
 Identities = 130/551 (23%), Positives = 199/551 (36%), Gaps = 100/551 (18%)

Query: 377  QTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALM 436
            +TC C   RW C   PC   C+      + TFD + ++  G+C+Y+L Q+ +   +  L 
Sbjct: 1938 ETCGC---RWTC---PCV--CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILH 1989

Query: 437  AVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITV------- 489
                  G        + V + +    + +  D  VT NG    +PY   N+ V       
Sbjct: 1990 NGACSPGARQGCMKSIEVKHSAL--SVELHSDMEVTVNGRLVSVPYVGGNMEVNVYGAIM 2047

Query: 490  ----FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFT 545
                F     H+   T    E  +QL P           F  +T GLCG  + +  +DF 
Sbjct: 2048 HEVRFNHLG-HIFTFTPQNNEFQLQLSP---------KTFASKTYGLCGICDENGANDFM 2097

Query: 546  TSMGIAEGTASLFVDSWRAGNCPAALERETDPCS--MSQLNKVCAETHCSMLLRTGTVFE 603
               G         V  W        ++R    C   + +   V   +HC +LL    +F 
Sbjct: 2098 LRDGTVTTDWKTLVQEW-------TVQRPGQTCQPILEEQCLVPDSSHCQVLLL--PLFA 2148

Query: 604  RCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIP 663
             CH  + PA FY  C   +C+ E+    +C  +  Y H C   GV +  WR+  D C + 
Sbjct: 2149 ECHKVLAPATFYAICQQDSCHQEQ----VCEVIASYAHLCRTNGVCV-DWRTP-DFCAMS 2202

Query: 664  CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQC-P 722
            C  +  +++    C R C       + C     P +GC CP    +  +G CV +  C  
Sbjct: 2203 CPPSLVYNHCEHGCPRHC---DGNVSSCGDH--PSEGCFCPPDKVM-LEGSCVPEEACTQ 2256

Query: 723  CILEG---YKFILAEQSTVINGITCHCINGR-LSCPQRPQMFLASCQAPKTFKSCSQSSE 778
            CI E    ++F+ A          C C++GR ++C  +P     + +AP T   C  +  
Sbjct: 2257 CIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNCTTQP---CPTAKAP-TCGLCEVARL 2312

Query: 779  NKFGAACAPTCQMLATGVAC------------VPTKCEPG-------CVCAEGLYENADG 819
             +    C P  + +   V+C             PT   PG       C C +   +    
Sbjct: 2313 RQNADQCCPEYECVCDPVSCDLPPVPHCERGLQPTLTNPGECRPNFTCACRKEECKRVSP 2372

Query: 820  QCVPPEE----------------CPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTH 863
               PP                  C C  S VS P G    T    C C+     C     
Sbjct: 2373 PSCPPHRLPTLRKTQCCDEYECACNCVNSTVSCPLGYLASTATNDCGCT--TTTCLPDKV 2430

Query: 864  CPSTCTLYGEG 874
            C    T+Y  G
Sbjct: 2431 CVHRSTIYPVG 2441



 Score =  112 bits (279), Expect = 6e-24
 Identities = 104/401 (25%), Positives = 153/401 (38%), Gaps = 68/401 (16%)

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
            TC C   RW C      P  CT     H++TFDGQ F   G+C Y+L        + +  
Sbjct: 1939 TCGC---RWTC------PCVCTGSSTRHIVTFDGQNFKLTGSCSYVL------FQNKEQD 1983

Query: 908  FKILTENVICG-NSGVTCSRAIKIFLGGLSVVL-ADRNYTVTGE---EPHVQLGVTP--- 959
             +++  N  C   +   C ++I++    LSV L +D   TV G     P+V   +     
Sbjct: 1984 LEVILHNGACSPGARQGCMKSIEVKHSALSVELHSDMEVTVNGRLVSVPYVGGNMEVNVY 2043

Query: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
            GA+   V  +  G        N    + +   +       GLCG  + N  +DF  R   
Sbjct: 2044 GAIMHEVRFNHLGHIFTFTPQNNEFQLQLS-PKTFASKTYGLCGICDENGANDFMLRDGT 2102

Query: 1020 VASSELELVNSWKES-------PLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATC 1072
            V +    LV  W          P+  +   V D               C V+    FA C
Sbjct: 2103 VTTDWKTLVQEWTVQRPGQTCQPILEEQCLVPD------------SSHCQVLLLPLFAEC 2150

Query: 1073 HSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYC- 1131
            H  +    +Y  C +D+C        E +C+ +A+YA  C   GVCVDWRTP FC + C 
Sbjct: 2151 HKVLAPATFYAICQQDSC------HQEQVCEVIASYAHLCRTNGVCVDWRTPDFCAMSCP 2204

Query: 1132 -GFYNTHTQDGHGEYQYTQEANCTWH-YQPCLCPSQPQSVPGSNI--EGCYNCSQDEYF- 1186
                  H + G   +     ++C  H  + C CP     + GS +  E C  C  ++   
Sbjct: 2205 PSLVYNHCEHGCPRHCDGNVSSCGDHPSEGCFCPPDKVMLEGSCVPEEACTQCIGEDGVQ 2264

Query: 1187 ---------DHEEGVCVPCMP----PTTPQPPTTPQLPTTG 1214
                     DH+      C+       T QP  T + PT G
Sbjct: 2265 HQFLEAWVPDHQPCQICTCLSGRKVNCTTQPCPTAKAPTCG 2305



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 98/372 (26%), Positives = 147/372 (39%), Gaps = 46/372 (12%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTF------SVQLRRGPDGSI---- 94
            C+     H  TFD   +  +G+C+Y+     +            S   R+G   SI    
Sbjct: 1950 CTGSSTRHIVTFDGQNFKLTGSCSYVLFQNKEQDLEVILHNGACSPGARQGCMKSIEVKH 2009

Query: 95   SRIIVELGASV-VTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
            S + VEL + + VTV+  ++SV        PY    +++  +G  +  V     L     
Sbjct: 2010 SALSVELHSDMEVTVNGRLVSV--------PYVGGNMEVNVYGAIMHEVRFN-HLGHIFT 2060

Query: 154  WGPDSH--LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQ-KLDDPG 210
            + P ++   + L  + +  +  GLCG  D    N+F+  +G      K    +  +  PG
Sbjct: 2061 FTPQNNEFQLQLSPKTFASKTYGLCGICDENGANDFMLRDGTVTTDWKTLVQEWTVQRPG 2120

Query: 211  EICTFQDIPSTHVRQAQHARICTQLLTLVAPECSVSKEP--FVLSCQADVAAAPQPGPQN 268
            + C         V  + H   C  LL  +  EC     P  F   CQ D         Q 
Sbjct: 2121 QTCQPILEEQCLVPDSSH---CQVLLLPLFAECHKVLAPATFYAICQQDSCH------QE 2171

Query: 269  SSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSCSS 328
              C  ++ Y+  C   G  V  WR+P  C++  CP + VY  C   C + C     SC  
Sbjct: 2172 QVCEVIASYAHLCRTNGVCVD-WRTPDFCAMS-CPPSLVYNHCEHGCPRHCDGNVSSCGD 2229

Query: 329  SCTFGCFCPEGTVLNDLSNNHTCVPVTQC-PCV-LHGAMYAPGEVTI---AACQTCRCTL 383
              + GCFCP   V+ + S    CVP   C  C+   G  +   E  +     CQ C C  
Sbjct: 2230 HPSEGCFCPPDKVMLEGS----CVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLS 2285

Query: 384  GRWV-CTERPCP 394
            GR V CT +PCP
Sbjct: 2286 GRKVNCTTQPCP 2297



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 97/369 (26%), Positives = 146/369 (39%), Gaps = 48/369 (13%)

Query: 858  CQQGTHCPST---CTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTEN 914
            C +GT   S+   C+L+G   V TFDG  + F G C Y+LA         + +F I+ + 
Sbjct: 22   CAEGTRGRSSTARCSLFGSDFVNTFDGSMYSFAGYCSYLLAGGC-----QKRSFSIIGD- 75

Query: 915  VICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD---ISIP 971
                 +G   S  + ++LG    +    N TVT  +  V +      L L  +     + 
Sbjct: 76   ---FQNGKRVS--LSVYLGEFFDIHLFVNGTVTQGDQRVSMPYASKGLYLETEAGYYKLS 130

Query: 972  GR-YNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNS 1030
            G  Y      +      + ++    +  CGLCGNFN   +DDF T+   + S   +  NS
Sbjct: 131  GEAYGFVARIDGSGNFQVLLSDRYFNKTCGLCGNFNIFAEDDFMTQEGTLTSDPYDFANS 190

Query: 1031 WKES---PLCGDVSFVTDPCSLNAFR-RSWAERKCSVINS-QTFATCHSKVYHLPYYEAC 1085
            W  S     C   S  +  C++++   +     +C ++ S   FA CH  V   P+   C
Sbjct: 191  WALSSGEQWCERASPPSSSCNISSGEMQKGLWEQCQLLKSTSVFARCHPLVDPEPFVALC 250

Query: 1086 VRDACGCDSGGDCECLCDAVAAYAQACLDKG-VCVDWRTPAFCPIYCGFYNTHTQDGHGE 1144
             +  C C   G  EC C A+  YA+ C  +G V   W   + C   C             
Sbjct: 251  EKTLCEC--AGGLECACPALLEYARTCAQEGMVLYGWTDHSACSPVC----------PAG 298

Query: 1145 YQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCYN-CSQDEYFDHEEGVCV-----PCMP 1198
             +Y Q   C     PC    Q   +     E C + CS  E    +EG+CV     PC+ 
Sbjct: 299  MEYRQ---CV---SPCARTCQSLHINEMCQERCVDGCSCPEGQLLDEGLCVESTECPCVH 352

Query: 1199 PTTPQPPTT 1207
                 PP T
Sbjct: 353  SGKRYPPGT 361



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 40/161 (24%), Positives = 63/161 (39%), Gaps = 32/161 (19%)

Query: 715  CVRKAQCPCILE---GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFK 771
            C     C C  +    Y  + A+   V+   T         CPQ       SC+  +  +
Sbjct: 1091 CESIGDCACFCDTIAAYAHVCAQHGKVVTWRTATL------CPQ-------SCEE-RNLR 1136

Query: 772  SCSQSSENKFGAACAPTCQMLATG---VACVPTKCEPGCV--CAEG-LYENADGQCVPPE 825
                  E ++ + CAP CQ+       +AC P +C  GC   C  G + +     CV PE
Sbjct: 1137 ENGYECEWRYNS-CAPACQVTCQHPEPLAC-PVQCVEGCHAHCPPGKILDELLQTCVDPE 1194

Query: 826  ECP-CEFSGVSYPGGAELHTD------CRTCSCSRGRWACQ 859
            +CP CE +G  +  G ++  +      C+ C C      C+
Sbjct: 1195 DCPVCEVAGRRFASGKKVTLNPSDPEHCQICHCDVVNLTCE 1235



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 4/71 (5%)

Query: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
            V +  C+G C S A ++I    V  +CSCC P  +   Q+ L C + S     ++  ++ 
Sbjct: 2745 VDIHYCQGKCASKAMYSIDINDVQDQCSCCSPTRTEPMQVALHCTNGSVVYHEVLNAME- 2803

Query: 2427 FSHCVCSSVAC 2437
               C CS   C
Sbjct: 2804 ---CKCSPRKC 2811



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 62/253 (24%), Positives = 85/253 (33%), Gaps = 54/253 (21%)

Query: 191  EGKFLEPHKFAALQKLDDPGEICTF--------QDIPSTHVRQAQHARICTQL----LTL 238
            EG F  P K   L+    P E CT                V   Q  +ICT L    +  
Sbjct: 2233 EGCFCPPDK-VMLEGSCVPEEACTQCIGEDGVQHQFLEAWVPDHQPCQICTCLSGRKVNC 2291

Query: 239  VAPECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVG---QPV---RRWR 292
                C  +K P    C+  VA   Q   Q        EY   C  V     PV    R  
Sbjct: 2292 TTQPCPTAKAPTCGLCE--VARLRQNADQ-----CCPEYECVCDPVSCDLPPVPHCERGL 2344

Query: 293  SPGLCSVGQCPANQVY----QECGSACVKTCSN------------PQHSCSSSCTFGCF- 335
             P L + G+C  N       +EC      +C               ++ C+ +C      
Sbjct: 2345 QPTLTNPGECRPNFTCACRKEECKRVSPPSCPPHRLPTLRKTQCCDEYECACNCVNSTVS 2404

Query: 336  CPEGTVLNDLSNNHTCVPVTQCP---CVLHGAMYAPGEVTIAACQTCRCT------LGRW 386
            CP G + +  +N+  C   T  P   CV    +Y  G+     C  C CT      +G  
Sbjct: 2405 CPLGYLASTATNDCGCTTTTCLPDKVCVHRSTIYPVGQFWEEGCDVCTCTDMEDAVMGLR 2464

Query: 387  V--CTERPCPGHC 397
            V  C+++PC   C
Sbjct: 2465 VAQCSQKPCEDSC 2477


>gi|169217460 PREDICTED: similar to Mucin-6, partial [Homo sapiens]
          Length = 350

 Score =  542 bits (1397), Expect = e-153
 Identities = 279/358 (77%), Positives = 296/358 (82%), Gaps = 9/358 (2%)

Query: 1425 TSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTI 1484
            TSF  TTTYPTPSHP+TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSAS HS PTGTI
Sbjct: 1    TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSTPTGTI 60

Query: 1485 PPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTT 1544
            PP TTL  TGSTHTAPP+TPTTSGTSQA SSFST KT TSLHSHTSSTHHPEVTPT+TT 
Sbjct: 61   PPLTTLMNTGSTHTAPPVTPTTSGTSQAASSFSTAKTSTSLHSHTSSTHHPEVTPTATTK 120

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPT 1604
            IT NPTS  + TP+AHT SATSSR   PFTTHSP TGSSP SSTGPMTATSF+TTTTYPT
Sbjct: 121  ITTNPTSIGSSTPMAHTTSATSSRLTTPFTTHSPSTGSSPVSSTGPMTATSFQTTTTYPT 180

Query: 1605 PSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGS 1664
            PS  QTTLPT+VPPFSTSLVTPSTHTVITP   QMATSASIHS PTGTIPPPTTLKATGS
Sbjct: 181  PSLSQTTLPTYVPPFSTSLVTPSTHTVITPPRTQMATSASIHSTPTGTIPPPTTLKATGS 240

Query: 1665 THTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGT- 1723
            THTAPT TLTTSGTSQALSSLNTAKTSTSLHSHTSSTHH EATSTSTTNITPNPTSTGT 
Sbjct: 241  THTAPTRTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHPEATSTSTTNITPNPTSTGTG 300

Query: 1724 PPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTP 1781
             P+  TTS TS        ++ +T   +H+  T    ++ST   + T  H +T   TP
Sbjct: 301  TPVAHTTSATS--------SRLTTPFTTHSPPTGSTPISSTGPVTATSFHATTTYPTP 350



 Score =  503 bits (1295), Expect = e-142
 Identities = 272/405 (67%), Positives = 299/405 (73%), Gaps = 55/405 (13%)

Query: 1594 TSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTI 1653
            TSF+TTTTYPTPSHPQTTLPTHVPPFSTS        ++TP         S H++ T   
Sbjct: 1    TSFQTTTTYPTPSHPQTTLPTHVPPFSTS--------LVTP---------STHTVIT--- 40

Query: 1654 PPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTN 1713
            P    +  + S H+ PT      GT   L++L           +T STH A         
Sbjct: 41   PTHAQMATSASIHSTPT------GTIPPLTTL----------MNTGSTHTA--------- 75

Query: 1714 ITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNH 1773
                      PP+T TTSGTSQ+ SSFSTAKTSTSLHSHTSSTHHPEVT T+TT IT N 
Sbjct: 76   ----------PPVTPTTSGTSQAASSFSTAKTSTSLHSHTSSTHHPEVTPTATTKITTNP 125

Query: 1774 TSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPH 1833
            TS G+ TP+AHTTSATSSRL TPFTTHSP TG++P+SSTGP+TATSFQTTTTYPTPS   
Sbjct: 126  TSIGSSTPMAHTTSATSSRLTTPFTTHSPSTGSSPVSSTGPMTATSFQTTTTYPTPSLSQ 185

Query: 1834 TTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAP 1893
            TTLPT+VP FSTSLVTPSTHTVI P  TQMATSASIHS PTGTIPPPTT+KATGSTHTAP
Sbjct: 186  TTLPTYVPPFSTSLVTPSTHTVITPPRTQMATSASIHSTPTGTIPPPTTLKATGSTHTAP 245

Query: 1894 PMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAH 1953
              T TTSGTSQ+ SS +TAKTSTSL  HTSSTHHPE T TSTTNITP  TSTGT TPVAH
Sbjct: 246  TRTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHPEATSTSTTNITPNPTSTGTGTPVAH 305

Query: 1954 TTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTP 1998
            TTSA+SSRL TPFTTHSPPTGS+P SSTGP+TATSF  TTTYPTP
Sbjct: 306  TTSATSSRLTTPFTTHSPPTGSTPISSTGPVTATSFHATTTYPTP 350



 Score =  462 bits (1189), Expect = e-129
 Identities = 247/359 (68%), Positives = 276/359 (76%), Gaps = 16/359 (4%)

Query: 1818 TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI 1877
            TSFQTTTTYPTPSHP TTLPTHVP FSTSLVTPSTHTVI PTH QMATSASIHS PTGTI
Sbjct: 1    TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSTPTGTI 60

Query: 1878 PPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTN 1937
            PP TT+  TGSTHTAPP+TPTTSGTSQ+ SSFSTAKTSTSL  HTSSTHHPEVTPT+TT 
Sbjct: 61   PPLTTLMNTGSTHTAPPVTPTTSGTSQAASSFSTAKTSTSLHSHTSSTHHPEVTPTATTK 120

Query: 1938 ITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPT 1997
            IT   TS G+ TP+AHTTSA+SSRL TPFTTHSP TGSSP SSTGPMTATSFQTTTTYPT
Sbjct: 121  ITTNPTSIGSSTPMAHTTSATSSRLTTPFTTHSPSTGSSPVSSTGPMTATSFQTTTTYPT 180

Query: 1998 PSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGS 2057
            PS  QTTLPT+VPPFSTSLVTPSTHTVI    TQMATSASIHSTPTGT+PPPTTLKATGS
Sbjct: 181  PSLSQTTLPTYVPPFSTSLVTPSTHTVITPPRTQMATSASIHSTPTGTIPPPTTLKATGS 240

Query: 2058 THTAPPMTVTTSGTSQTHSSFSTATASSSFIS--SSSWLPQNSSSRPPSSPITTQLPHLS 2115
            THTAP  T+TTSGTSQ  SS +TA  S+S  S  SS+  P+ +S+   S+   T  P  +
Sbjct: 241  THTAPTRTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHPEATST---STTNITPNPTST 297

Query: 2116 SATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT 2174
               TPV+ T   +SS   +P           ++HS P  S+P + ++    +   H+TT
Sbjct: 298  GTGTPVAHTTSATSSRLTTPF----------TTHSPPTGSTP-ISSTGPVTATSFHATT 345



 Score =  361 bits (926), Expect = 6e-99
 Identities = 209/363 (57%), Positives = 232/363 (63%), Gaps = 24/363 (6%)

Query: 1251 QTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPT-------ATLRSTATKPTVTQ 1303
            QT     T +  + T  +  PP  T+ VTP   + + PT       A++ ST T      
Sbjct: 4    QTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSTPTGTIPPL 63

Query: 1304 ATTRATAST-ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGP 1362
             T   T ST  +P  T T   T++   +  T  TS +  +   ST+   P  T T TT  
Sbjct: 64   TTLMNTGSTHTAPPVTPTTSGTSQAASSFSTAKTSTSLHSHTSSTHH--PEVTPTATT-- 119

Query: 1363 RPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPV 1422
                  TT PT+     P   T T  T +R TT       P TTHSP T  SPV STGP+
Sbjct: 120  ----KITTNPTSIGSSTPMAHT-TSATSSRLTT-------PFTTHSPSTGSSPVSSTGPM 167

Query: 1423 TATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTG 1482
            TATSF  TTTYPTPS  +TTLPT+VPPFSTSLVTPSTHTVITP   QMATSAS HS PTG
Sbjct: 168  TATSFQTTTTYPTPSLSQTTLPTYVPPFSTSLVTPSTHTVITPPRTQMATSASIHSTPTG 227

Query: 1483 TIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST 1542
            TIPPPTTLKATGSTHTAP  T TTSGTSQA SS +T KT TSLHSHTSSTHHPE T TST
Sbjct: 228  TIPPPTTLKATGSTHTAPTRTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHPEATSTST 287

Query: 1543 TTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTY 1602
            T ITPNPTST T TPVAHT SATSSR   PFTTHSPPTGS+P SSTGP+TATSF  TTTY
Sbjct: 288  TNITPNPTSTGTGTPVAHTTSATSSRLTTPFTTHSPPTGSTPISSTGPVTATSFHATTTY 347

Query: 1603 PTP 1605
            PTP
Sbjct: 348  PTP 350



 Score =  247 bits (630), Expect = 1e-64
 Identities = 169/384 (44%), Positives = 210/384 (54%), Gaps = 69/384 (17%)

Query: 1987 TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTV 2046
            TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI  TH QMATSASIHSTPTGT+
Sbjct: 1    TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSTPTGTI 60

Query: 2047 PPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSP 2106
            PP TTL  TGSTHTAPP+T TTSGTSQ  SSFSTA  S+S  S +S     S+  P  +P
Sbjct: 61   PPLTTLMNTGSTHTAPPVTPTTSGTSQAASSFSTAKTSTSLHSHTS-----STHHPEVTP 115

Query: 2107 ITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFV 2166
                     +ATT ++T              P+++ S  P +H++  TSS         +
Sbjct: 116  ---------TATTKITTN-------------PTSIGSSTPMAHTTSATSSR--------L 145

Query: 2167 SAPVHSTTLSSGSHSSLSTHPTTA-SVSASPLFPSSPAASTTIRATLPHTISSPFTLSAL 2225
            + P  + + S+GS    ST P TA S   +  +P+   + TT+   +P     PF+ S +
Sbjct: 146  TTPFTTHSPSTGSSPVSSTGPMTATSFQTTTTYPTPSLSQTTLPTYVP-----PFSTSLV 200

Query: 2226 LPISTVTVSPTPSSHLASS---------TIAFPSTPRTTASTHTAP-----------AFS 2265
             P ST TV   P + +A+S         TI  P+T + T STHTAP           A S
Sbjct: 201  TP-STHTVITPPRTQMATSASIHSTPTGTIPPPTTLKATGSTHTAPTRTLTTSGTSQALS 259

Query: 2266 SQSTTSRSTSLTTRVPTSGFVSLTS----GVTGIPTSPVTNLTTRHPGPTLSPTTRFLTS 2321
            S +T   STSL +   ++     TS     +T  PTS  T     H   T S T+  LT+
Sbjct: 260  SLNTAKTSTSLHSHTSSTHHPEATSTSTTNITPNPTSTGTGTPVAH---TTSATSSRLTT 316

Query: 2322 SLTAHGSTPASAPVSSLGTPTPTS 2345
              T H     S P+SS G  T TS
Sbjct: 317  PFTTHSPPTGSTPISSTGPVTATS 340



 Score =  103 bits (256), Expect = 3e-21
 Identities = 93/300 (31%), Positives = 126/300 (42%), Gaps = 67/300 (22%)

Query: 1199 PTTPQPPTTPQLPTTGSRPTQ--VWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256
            PT   PP T  L  TGS  T   V P T  ++      ST  + +S H+  S T  P + 
Sbjct: 56   PTGTIPPLTT-LMNTGSTHTAPPVTPTTSGTSQAASSFSTAKTSTSLHSHTSSTHHPEVT 114

Query: 1257 ATLT---SSKPTASSGEPP-------------------RPTTAVTPQATSGLPPTATLRS 1294
             T T   ++ PT+     P                    P+T  +P +++G     + ++
Sbjct: 115  PTATTKITTNPTSIGSSTPMAHTTSATSSRLTTPFTTHSPSTGSSPVSSTGPMTATSFQT 174

Query: 1295 TATKPT---------------VTQATTRATASTASPATTSTAQST---TRTTMTLPTPAT 1336
            T T PT                T   T +T +  +P  T  A S    +  T T+P P T
Sbjct: 175  TTTYPTPSLSQTTLPTYVPPFSTSLVTPSTHTVITPPRTQMATSASIHSTPTGTIPPPTT 234

Query: 1337 ---SGTSPTLP------KSTNQELPGTTATQTT-----------GPRPTPASTTGPTTPQ 1376
               +G++ T P        T+Q L      +T+            P  T  STT   TP 
Sbjct: 235  LKATGSTHTAPTRTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHPEATSTSTTN-ITPN 293

Query: 1377 PGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTP 1436
            P      T    T + T++  T   TP TTHSPPT  +P+ STGPVTATSFHATTTYPTP
Sbjct: 294  PTSTGTGTPVAHTTSATSSRLT---TPFTTHSPPTGSTPISSTGPVTATSFHATTTYPTP 350



 Score =  100 bits (249), Expect = 2e-20
 Identities = 111/396 (28%), Positives = 169/396 (42%), Gaps = 67/396 (16%)

Query: 1907 SSFSTAKT-------STSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSAS- 1958
            +SF T  T        T+LP H        VTP++ T ITP H    T   +  T + + 
Sbjct: 1    TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSTPTGTI 60

Query: 1959 ---SSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTT-TTYPTPSHPQTTLPTHVPPFST 2014
               ++ + T  T  +PP   +P +S     A+SF T  T+    SH  +T    V P +T
Sbjct: 61   PPLTTLMNTGSTHTAPPV--TPTTSGTSQAASSFSTAKTSTSLHSHTSSTHHPEVTPTAT 118

Query: 2015 SLVTPSTHTVIITT---HTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGT 2071
            + +T +  ++  +T   HT  ATS+ + +TP  T  P T      ST    PMT T+  T
Sbjct: 119  TKITTNPTSIGSSTPMAHTTSATSSRL-TTPFTTHSPSTGSSPVSST---GPMTATSFQT 174

Query: 2072 SQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSF 2131
            + T+      T S S  +  +++P      P S+ + T  P   +  TP  T    S+S 
Sbjct: 175  TTTY-----PTPSLSQTTLPTYVP------PFSTSLVT--PSTHTVITPPRTQMATSASI 221

Query: 2132 SPSPSA---PSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPT 2188
              +P+    P T      S+H++P  +  + GTS +  S     T+ S  SH+S + HP 
Sbjct: 222  HSTPTGTIPPPTTLKATGSTHTAPTRTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHPE 281

Query: 2189 TASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAF 2248
              S S + + P+                          P ST T   TP +H  S+T + 
Sbjct: 282  ATSTSTTNITPN--------------------------PTSTGT--GTPVAHTTSATSSR 313

Query: 2249 PSTPRTTAS--THTAPAFSSQSTTSRSTSLTTRVPT 2282
             +TP TT S  T + P  S+   T+ S   TT  PT
Sbjct: 314  LTTPFTTHSPPTGSTPISSTGPVTATSFHATTTYPT 349



 Score =  100 bits (249), Expect = 2e-20
 Identities = 102/363 (28%), Positives = 144/363 (39%), Gaps = 42/363 (11%)

Query: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTAS---- 1267
            TT + PT   P T   T +   S++  +PS+ HT  +PT   +  +    S PT +    
Sbjct: 5    TTTTYPTPSHPQTTLPTHVPPFSTSLVTPST-HTVITPTHAQMATSASIHSTPTGTIPPL 63

Query: 1268 ----------SGEPPRPTTAVTPQATSGLPPTATLRSTATK----------PTVTQATTR 1307
                      +  P  PTT+ T QA S      T  S  +           PT T   T 
Sbjct: 64   TTLMNTGSTHTAPPVTPTTSGTSQAASSFSTAKTSTSLHSHTSSTHHPEVTPTATTKITT 123

Query: 1308 ATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTT-ATQTTGPRPTP 1366
               S  S    +   S T + +T P    S ++ + P S+   +  T+  T TT P P+ 
Sbjct: 124  NPTSIGSSTPMAHTTSATSSRLTTPFTTHSPSTGSSPVSSTGPMTATSFQTTTTYPTPSL 183

Query: 1367 ASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATS 1426
            + TT PT   P   +    T +T T  T   T   T  + HS PT   P P+T   T ++
Sbjct: 184  SQTTLPTYVPPFSTS--LVTPSTHTVITPPRTQMATSASIHSTPTGTIPPPTTLKATGST 241

Query: 1427 FHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPP 1486
              A T   T S     L +     +T+  + S H+  + TH   ATS S     T   P 
Sbjct: 242  HTAPTRTLTTSGTSQALSS----LNTAKTSTSLHSHTSSTHHPEATSTST----TNITPN 293

Query: 1487 PTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTIT 1546
            PT      ST T  P+  TTS TS   ++  T  +P +  +  SST     T    TT  
Sbjct: 294  PT------STGTGTPVAHTTSATSSRLTTPFTTHSPPTGSTPISSTGPVTATSFHATTTY 347

Query: 1547 PNP 1549
            P P
Sbjct: 348  PTP 350


>gi|239755545 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2852

 Score =  512 bits (1318), Expect = e-144
 Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104
            C  WG  H  TFD   Y  SG  +Y      +    +FS+Q+   P    S        S
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138

Query: 105  VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159
            +  V E  I + K++   G+ + LP+     ++    Q    V  + +    + W   S 
Sbjct: 139  LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 195

Query: 160  LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214
            + + +  + +G   GLCGN +    ++ V+  GK  +      H +        PG   T
Sbjct: 196  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 253

Query: 215  FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266
               +P     Q     +      C  LL      C   VS  PF  SC +D+  +   G 
Sbjct: 254  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 311

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325
              + C  L+EY+R C+  G+P++ WR+    C+V        Y EC + C  +C +P+ S
Sbjct: 312  VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 370

Query: 326  CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
            C  S   C  GC+CP G +  D      CV   +CPC  HG +Y PG V    C TC CT
Sbjct: 371  CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 426

Query: 383  LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442
             G+W C+   CP  CS+ G    TTFD R Y F  TC YIL +S      G        +
Sbjct: 427  SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 483

Query: 443  --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496
              G++     + +V  +  QD   ++ ++Q   V    + K +P Y      + R +S  
Sbjct: 484  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 543

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L++ T+ G+ ++   R   + Y+ V  ++   T GLCG FNG+T DDF + +G+ E T  
Sbjct: 544  LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 557  LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614
            LF +SW+  +   P       DPC +       +   CS+L  TG +F  C A ++P P+
Sbjct: 603  LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 660

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
            +++C   AC   +  P +CA L  Y H C   G+ +  +R+ +  C + C  +  +S   
Sbjct: 661  FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 717

Query: 675  QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721
              C RTC  L+                EC      V+GC CP  TYL+ + + CV + QC
Sbjct: 718  APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 771

Query: 722  PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781
             C  +G  +   +      G  CHC +G +SC  R     A+C A + F +CS    +  
Sbjct: 772  SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 827

Query: 782  GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
              +   TC Q L          C  GC C +GL  + D  C  PEECPC + G  Y  G 
Sbjct: 828  ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 886

Query: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
            ++ + C TC C RG + C     C STCT YG+ H  TFDG  F F G C+  L      
Sbjct: 887  QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945

Query: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959
            V+     F ++ ENV C +SG+ C + I I +G   +V  D +   + E     +  V  
Sbjct: 946  VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1000

Query: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
              +     +  P  + +TL+W++  T+ ++     Q  L GLCGNF+    ++  T    
Sbjct: 1001 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059

Query: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079
              ++  E  +SW     C D     D C LN  R  +A+++CS++ S+ F  CH  V   
Sbjct: 1060 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1118

Query: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139
             +Y  C+ D CGC  GGDCEC C +V+AYA  C   GV VDWRTP  CP  C F+N    
Sbjct: 1119 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1177

Query: 1140 DGHGEYQYTQEA 1151
             G G YQ +  A
Sbjct: 1178 -GKGPYQLSSLA 1188



 Score =  226 bits (577), Expect = 2e-58
 Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%)

Query: 397  CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454
            C   G   V TFD   Y   G  +Y L+   +       + V++  + G S    S    
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138

Query: 455  VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514
            ++   + +I ++++  VT+ G    LP+           S  LQ    +   ++V+ +  
Sbjct: 139  LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 185

Query: 515  FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566
            F          Y+ + P+  G T GLCGN N D  DD  TS G        FV SW+   
Sbjct: 186  FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 243

Query: 567  CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625
               A  +   P + S     C + +   +     V+E+C A + P        + AC+ Y
Sbjct: 244  --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 291

Query: 626  EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685
                P                              T  CT +             C S+ 
Sbjct: 292  VSPLPF-----------------------------TASCTSDL------------CQSMG 310

Query: 686  DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745
            D AT C   A     C                 AQ    L+G++       T +   T H
Sbjct: 311  DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 346

Query: 746  CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805
            C         + + F        T+  C         A+C P    + + +ACV      
Sbjct: 347  C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 380

Query: 806  GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
            GC C  GL    DG CV P ECPCEF G  YP G+ +  DC TC+C+ G+W C     CP
Sbjct: 381  GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 438

Query: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924
            + C++ G+ H  TFDG+R+ F   C+YILA      + S  TF +  +N  CG N    C
Sbjct: 439  AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 493

Query: 925  SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977
             +++ + L       V L      +  ++  +    T  A  +     V + +     + 
Sbjct: 494  VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 553

Query: 978  LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036
            ++++R  + + +++ +   +   GLCG FNGN +DDF +      S+     NSWK    
Sbjct: 554  VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 613

Query: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094
            C  +      DPC ++    S++ + CSV+  + FA C + +  +PY+E C RDAC C  
Sbjct: 614  CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 673

Query: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152
                 CLC  +A YA  C   G+ VD+R   PA C + C                     
Sbjct: 674  ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 708

Query: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195
             +  Y PC+ P        + P++  V G +       +EGC  C  D Y D +  +CVP
Sbjct: 709  ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 767

Query: 1196 -----CMPPTTPQPPTTPQLPTTG 1214
                 C       PP    +P+ G
Sbjct: 768  RNQCSCHFQGVDYPPGDSDIPSLG 791



 Score =  118 bits (295), Expect = 8e-26
 Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%)

Query: 38  TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92
           TA    +CS  G  HF+TFD   Y F  TC YI A +      TF+V L+  P G     
Sbjct: 434 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 491

Query: 93  ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147
               S+S I+ +     VT+++A  + + D   I  PYT +  +I     S   +  +  
Sbjct: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 549

Query: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205
           + + V++  +   L + V+++++    GLCG F+G   ++F+S  G     P  F    K
Sbjct: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609

Query: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259
                 P    +  D    H++ A ++ + C+ L   +   CS  +S  P+   C+ D  
Sbjct: 610 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669

Query: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318
              QP      CATL+ Y+  C   G PV  R R P  C++  C A++ Y  C + C +T
Sbjct: 670 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 723

Query: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
           C +     +C            C  GC CP  T L+  ++   CVP  QC C   G  Y 
Sbjct: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 781

Query: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409
           PG+  I +   C C  G   C  R  P      G  FV   D
Sbjct: 782 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 822



 Score =  111 bits (277), Expect = 1e-23
 Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%)

Query: 802  KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859
            KC P  +  C  G      G+CV P  C C     + P               R +    
Sbjct: 32   KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 70

Query: 860  QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917
             G    S C  +G+ HV TFDG  +   G   Y L     G ++ +  +F I   N   C
Sbjct: 71   AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 126

Query: 918  GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974
            G+S  TCSRA+ +F  G   +   +  T  G   + PHV        L+  V +     +
Sbjct: 127  GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 186

Query: 975  NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034
              TL W+    + I+++        GLCGN N + KDD  T S  +    +E V+SW+E 
Sbjct: 187  --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 244

Query: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088
                 P     S    PC   N         +C  +    F  CH+ V  LP+  +C  D
Sbjct: 245  APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 304

Query: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146
               C S GD    C A+A YA+AC   G  +  WRT    C ++C             + 
Sbjct: 305  L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 353

Query: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199
            Y +   C     P  C  +   V    + ++GCY C     F  E+G CV     PC   
Sbjct: 354  YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 406

Query: 1200 TTPQPP 1205
             T  PP
Sbjct: 407  GTLYPP 412



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 176/738 (23%), Positives = 253/738 (34%), Gaps = 116/738 (15%)

Query: 1153 CTWHYQPCLCP----------SQPQSVPGSNIEGCYN-CSQDEYFDHEEGVCV---PCMP 1198
            C W Y  C  P          +  + VP   +EGC   C   +  D     CV    C+ 
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVP--RVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393

Query: 1199 PTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPS-SNHTPASPTQTPLLPA 1257
            P    P  T  L      P+Q           GL + +   P  S  +P +PT  P    
Sbjct: 1394 PAVWVP--TEALGNETLPPSQ-----------GLPTPSDEEPQLSQESPRTPTHRP---- 1436

Query: 1258 TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPAT 1317
             LT + P  ++  PP  T    P  + G  PT T      + T +Q     T S AS   
Sbjct: 1437 ALTPAAPLTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGV 1493

Query: 1318 TSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQP 1377
            T++  +   T  +   P    T      S   E    T      P  T +S    + P P
Sbjct: 1494 TASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAP 1550

Query: 1378 GQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPS 1437
              P    A       +    TTP  P  T SP  +  PV S G ++ +        PT S
Sbjct: 1551 RFPLMTKAVTVRGHGSLPVRTTPPQPSLTASP--SSRPVASPGAISRS--------PTSS 1600

Query: 1438 HPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTH 1497
                           +++TP+   VI+ T     T A + S+P+      T L   G+  
Sbjct: 1601 GSH-----------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAA 1643

Query: 1498 TAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTP 1557
               P++P    T       ST K     HS       P  +P S     P+P  +    P
Sbjct: 1644 EQVPVSPL--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRP 1691

Query: 1558 VAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTL 1612
              HT  AT S   PP T    P  +S  ++T  + AT F +  +T P+       P T+L
Sbjct: 1692 AQHTTMATRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSL 1747

Query: 1613 PTHVPPFSTSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670
            P      S  + T  P    + TP   Q  T  +    P     P    +A   TH AP 
Sbjct: 1748 PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP- 1806

Query: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730
                 +GT+  L    T  TS  L         AE T+ S  ++ P  ++TG   + + +
Sbjct: 1807 ---PAAGTAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILS 1853

Query: 1731 SGTSQSRSSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAH 1784
               S   S + +A+      T  + H  T     PE     T    P  TS       A 
Sbjct: 1854 KQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSAR 1911

Query: 1785 TTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFS 1844
            T    S  +  P    +  T   P  +  PV     + TT     S P  ++   +    
Sbjct: 1912 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEAL 1967

Query: 1845 TSLVTPSTHTVIIPTHTQ 1862
             +    +T T  +P   Q
Sbjct: 1968 ATTTEANTSTTCVPIAEQ 1985



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%)

Query: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568
            SQ   + S  +   S  S  + TH P +TP +  T   NP  T T  PV     + T+ +
Sbjct: 1411 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1470

Query: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628
             P   T    P G +   ++  +TA+      T P  S     L T  P   +  +  + 
Sbjct: 1471 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1529

Query: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS---THTAPTMTLTTSGTSQAL 1682
             TVI      +  S+   S P    P  T   T++  GS     T P  +LT S +S+ +
Sbjct: 1530 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPV 1587

Query: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737
            +S    +++ TS  SH +    A     S T + P PT   S  +P   +T +GT+  + 
Sbjct: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1646

Query: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
              S  +T      L +      H +    S  S  P+   +    P  HTT AT S    
Sbjct: 1647 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1705

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850
            P T    P   +  ++T  + AT F +  +T P+       P T+LP      S  + TP
Sbjct: 1706 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1761

Query: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908
                 +I T  Q   +    ++P  T+ P  P T  A    H    + P  +GT+     
Sbjct: 1762 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1817

Query: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968
             +T  TS  LP    +         S  ++ P+ ++TG    ++   S     LPT    
Sbjct: 1818 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1862

Query: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024
                 GS+    T    ATS   T     P   Q  T LP    P S +L   S  T   
Sbjct: 1863 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1915

Query: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082
              ++    Q+A +    + P     P        S  +AP +++   G ++  ++ + A 
Sbjct: 1916 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 1974

Query: 2083 ASSSFI 2088
             S++ +
Sbjct: 1975 TSTTCV 1980



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%)

Query: 344  DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388
            + + + TCVP+ +  CV H  +     + +   Q C       RC +        G   C
Sbjct: 1972 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2030

Query: 389  TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446
                C   CS+       TFD           YIL QSP   ++   + V D   + + H
Sbjct: 2031 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2087

Query: 447  SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502
                   +V L+      ++ I + +  VT + +  W P       +  + + H+ M  +
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2145

Query: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559
                 +  L       V      + Q  GLCG  +GD  +D T   G   G A   + F+
Sbjct: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205

Query: 560  DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611
            DSW+             P S++ + +       CA T CS  LR  +   F  CH  V P
Sbjct: 2206 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2253

Query: 612  APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671
              F +  +      ++     C AL  YV  C    V +  WR S D C   C+ ++T+ 
Sbjct: 2254 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2307

Query: 672  YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726
                ACE  +TC        +  H  V  +GC C +GT L+++    C+ +A+C C    
Sbjct: 2308 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2367

Query: 727  GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
            G    L E     N     C   +   P         C +P+  +SC +  E    A   
Sbjct: 2368 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2420

Query: 787  PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830
            PT      G  CV   T CE   P C     L  +  +  C P   C C+
Sbjct: 2421 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2470



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98
            P    C+ +G  H+ TFD   +DF G C  ++  +T   +F      +     G I R  
Sbjct: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 967

Query: 99   VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +      + V  ++I   D      P  +  +  ++  +      +    +  + ++W  
Sbjct: 968  IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1022

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209
             + + V    ++ GQ+ GLCGNFD K  NE  + E  +   P +F    AA++  D  DP
Sbjct: 1023 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1082

Query: 210  GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267
             ++C    +     R+    + C+ LL+ V   C   V    F  +C  D     Q G  
Sbjct: 1083 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137

Query: 268  NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297
               CA++S Y+ QC   G  V  WR+P LC
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 124/521 (23%), Positives = 202/521 (38%), Gaps = 76/521 (14%)

Query: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931
            T+PP    PT            P TPT       P+    A  +T+L    ++T  P V+
Sbjct: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1461

Query: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985
            P  T T +      T ++ P   T S +S  +        H+P + S P +   P   M 
Sbjct: 1462 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1521

Query: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
            + + +TT  T      P  T+ +  PP                  T+  T     S P  
Sbjct: 1522 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1570

Query: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS---SS 2100
            T PP  +L A+ S+   A P  ++ S TS + S  +  T + + + S + +PQ +   S+
Sbjct: 1571 TTPPQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1629

Query: 2101 RPPSSPITT------QLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143
              PS+P+T       Q+P            LS+       +  + S  SP P  P   + 
Sbjct: 1630 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1688

Query: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
              P+ H++  T SP          S+ T++  ++A    +  S+     LS  P   S+ 
Sbjct: 1689 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1748

Query: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245
             + +  S+P A+   +A++  T   P        TLS +LP +   ++   P +H+A   
Sbjct: 1749 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1808

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
                      A+  T+        T+   S+  R  T+G V++ S    +PTS      +
Sbjct: 1809 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1865

Query: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
               GPT L+P T    + L A    P  A   +   P PTS
Sbjct: 1866 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1902



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%)

Query: 117  DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175
            D+  +  P +  G +I   G    ++      ++++ W   S LM++   K    Q  GL
Sbjct: 2119 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2175

Query: 176  CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228
            CG  DG   N+   ++G        + +   +DP        +PS  T V Q +      
Sbjct: 2176 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2227

Query: 229  -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281
                C+  L +V      A    V  E F      D     QP      C  L+ Y   C
Sbjct: 2228 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2281

Query: 282  SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332
                  +  WR    C    C ++  YQ C +AC   KTC        +P+H        
Sbjct: 2282 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2337

Query: 333  GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379
            GC C EGT+L+   ++  C+P  +C C    G   A GE   ++   C
Sbjct: 2338 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%)

Query: 794  TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847
            T   CVP   E  CV   C EG L      Q  P    P  C   G++   G +      
Sbjct: 1975 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2033

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
             C+C                C+++ +   +TFDG          YIL         SQ  
Sbjct: 2034 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2069

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967
             ++LT +V+       C  A    L      L   N T      H+   VT    +  V 
Sbjct: 2070 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2117

Query: 968  ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003
            + +        RY   +    HM                   +++  ++ S+    GLCG
Sbjct: 2118 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2177

Query: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057
              +G+  +D   +   V   A      ++SW+        G   F  D C         A
Sbjct: 2178 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2228

Query: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113
               CS    +++++TF+ CH  V    + E  +RD             C A+  Y   C 
Sbjct: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2282

Query: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137
               VC++WR   +CP  C   +T+
Sbjct: 2283 KFHVCIEWRRSDYCPFLCSSDSTY 2306



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 58/270 (21%), Positives = 106/270 (39%), Gaps = 22/270 (8%)

Query: 2088 ISSSSWLPQNS---SSRPPSSPITT---QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV 2141
            +  + W+P  +    + PPS  + T   + P LS  +    T        + +P+AP T 
Sbjct: 1392 VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP-----ALTPAAPLTT 1446

Query: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT--LSSGSHSSLSTHPTTASVSASPLFP 2199
            +   P + +     SP  G + + +  P+  T   L +G   S ++   TAS+ A P  P
Sbjct: 1447 ALNPPVTATEEPVVSP--GPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504

Query: 2200 SSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259
             S +    ++   P  +S     + +    TV  + +P+  ++S +   P  P  T +  
Sbjct: 1505 ESSSLPVALQTPTPGMVSGAMETTRV----TVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560

Query: 2260 TAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFL 2319
                 S    T+      T  P+S  V+    ++  PTS  ++     P  T   +   +
Sbjct: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620

Query: 2320 TSSLTAHGSTPASAPVSSLGT---PTPTSP 2346
                 A  ++  S P++  GT     P SP
Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSP 1650



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
            V +  C+G C SA+ +N         C CCR +    + ++L C   +T    +  T+Q 
Sbjct: 2787 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2843

Query: 2427 FSHCVC 2432
             + C C
Sbjct: 2844 PTDCAC 2849


>gi|239755543 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2924

 Score =  512 bits (1318), Expect = e-144
 Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104
            C  WG  H  TFD   Y  SG  +Y      +    +FS+Q+   P    S        S
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210

Query: 105  VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159
            +  V E  I + K++   G+ + LP+     ++    Q    V  + +    + W   S 
Sbjct: 211  LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 267

Query: 160  LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214
            + + +  + +G   GLCGN +    ++ V+  GK  +      H +        PG   T
Sbjct: 268  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 325

Query: 215  FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266
               +P     Q     +      C  LL      C   VS  PF  SC +D+  +   G 
Sbjct: 326  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 383

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325
              + C  L+EY+R C+  G+P++ WR+    C+V        Y EC + C  +C +P+ S
Sbjct: 384  VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 442

Query: 326  CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
            C  S   C  GC+CP G +  D      CV   +CPC  HG +Y PG V    C TC CT
Sbjct: 443  CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 498

Query: 383  LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442
             G+W C+   CP  CS+ G    TTFD R Y F  TC YIL +S      G        +
Sbjct: 499  SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 555

Query: 443  --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496
              G++     + +V  +  QD   ++ ++Q   V    + K +P Y      + R +S  
Sbjct: 556  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 615

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L++ T+ G+ ++   R   + Y+ V  ++   T GLCG FNG+T DDF + +G+ E T  
Sbjct: 616  LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 557  LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614
            LF +SW+  +   P       DPC +       +   CS+L  TG +F  C A ++P P+
Sbjct: 675  LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 732

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
            +++C   AC   +  P +CA L  Y H C   G+ +  +R+ +  C + C  +  +S   
Sbjct: 733  FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 789

Query: 675  QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721
              C RTC  L+                EC      V+GC CP  TYL+ + + CV + QC
Sbjct: 790  APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 843

Query: 722  PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781
             C  +G  +   +      G  CHC +G +SC  R     A+C A + F +CS    +  
Sbjct: 844  SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 899

Query: 782  GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
              +   TC Q L          C  GC C +GL  + D  C  PEECPC + G  Y  G 
Sbjct: 900  ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 958

Query: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
            ++ + C TC C RG + C     C STCT YG+ H  TFDG  F F G C+  L      
Sbjct: 959  QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017

Query: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959
            V+     F ++ ENV C +SG+ C + I I +G   +V  D +   + E     +  V  
Sbjct: 1018 VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1072

Query: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
              +     +  P  + +TL+W++  T+ ++     Q  L GLCGNF+    ++  T    
Sbjct: 1073 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1131

Query: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079
              ++  E  +SW     C D     D C LN  R  +A+++CS++ S+ F  CH  V   
Sbjct: 1132 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1190

Query: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139
             +Y  C+ D CGC  GGDCEC C +V+AYA  C   GV VDWRTP  CP  C F+N    
Sbjct: 1191 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1249

Query: 1140 DGHGEYQYTQEA 1151
             G G YQ +  A
Sbjct: 1250 -GKGPYQLSSLA 1260



 Score =  226 bits (577), Expect = 2e-58
 Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%)

Query: 397  CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454
            C   G   V TFD   Y   G  +Y L+   +       + V++  + G S    S    
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210

Query: 455  VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514
            ++   + +I ++++  VT+ G    LP+           S  LQ    +   ++V+ +  
Sbjct: 211  LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 257

Query: 515  FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566
            F          Y+ + P+  G T GLCGN N D  DD  TS G        FV SW+   
Sbjct: 258  FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 315

Query: 567  CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625
               A  +   P + S     C + +   +     V+E+C A + P        + AC+ Y
Sbjct: 316  --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 363

Query: 626  EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685
                P                              T  CT +             C S+ 
Sbjct: 364  VSPLPF-----------------------------TASCTSDL------------CQSMG 382

Query: 686  DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745
            D AT C   A     C                 AQ    L+G++       T +   T H
Sbjct: 383  DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 418

Query: 746  CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805
            C         + + F        T+  C         A+C P    + + +ACV      
Sbjct: 419  C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 452

Query: 806  GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
            GC C  GL    DG CV P ECPCEF G  YP G+ +  DC TC+C+ G+W C     CP
Sbjct: 453  GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 510

Query: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924
            + C++ G+ H  TFDG+R+ F   C+YILA      + S  TF +  +N  CG N    C
Sbjct: 511  AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 565

Query: 925  SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977
             +++ + L       V L      +  ++  +    T  A  +     V + +     + 
Sbjct: 566  VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 625

Query: 978  LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036
            ++++R  + + +++ +   +   GLCG FNGN +DDF +      S+     NSWK    
Sbjct: 626  VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 685

Query: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094
            C  +      DPC ++    S++ + CSV+  + FA C + +  +PY+E C RDAC C  
Sbjct: 686  CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 745

Query: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152
                 CLC  +A YA  C   G+ VD+R   PA C + C                     
Sbjct: 746  ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 780

Query: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195
             +  Y PC+ P        + P++  V G +       +EGC  C  D Y D +  +CVP
Sbjct: 781  ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 839

Query: 1196 -----CMPPTTPQPPTTPQLPTTG 1214
                 C       PP    +P+ G
Sbjct: 840  RNQCSCHFQGVDYPPGDSDIPSLG 863



 Score =  118 bits (295), Expect = 8e-26
 Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%)

Query: 38  TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92
           TA    +CS  G  HF+TFD   Y F  TC YI A +      TF+V L+  P G     
Sbjct: 506 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 563

Query: 93  ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147
               S+S I+ +     VT+++A  + + D   I  PYT +  +I     S   +  +  
Sbjct: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 621

Query: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205
           + + V++  +   L + V+++++    GLCG F+G   ++F+S  G     P  F    K
Sbjct: 622 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 681

Query: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259
                 P    +  D    H++ A ++ + C+ L   +   CS  +S  P+   C+ D  
Sbjct: 682 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741

Query: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318
              QP      CATL+ Y+  C   G PV  R R P  C++  C A++ Y  C + C +T
Sbjct: 742 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 795

Query: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
           C +     +C            C  GC CP  T L+  ++   CVP  QC C   G  Y 
Sbjct: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 853

Query: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409
           PG+  I +   C C  G   C  R  P      G  FV   D
Sbjct: 854 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 894



 Score =  111 bits (277), Expect = 1e-23
 Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%)

Query: 802  KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859
            KC P  +  C  G      G+CV P  C C     + P               R +    
Sbjct: 104  KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 142

Query: 860  QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917
             G    S C  +G+ HV TFDG  +   G   Y L     G ++ +  +F I   N   C
Sbjct: 143  AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 198

Query: 918  GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974
            G+S  TCSRA+ +F  G   +   +  T  G   + PHV        L+  V +     +
Sbjct: 199  GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 258

Query: 975  NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034
              TL W+    + I+++        GLCGN N + KDD  T S  +    +E V+SW+E 
Sbjct: 259  --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 316

Query: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088
                 P     S    PC   N         +C  +    F  CH+ V  LP+  +C  D
Sbjct: 317  APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 376

Query: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146
               C S GD    C A+A YA+AC   G  +  WRT    C ++C             + 
Sbjct: 377  L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 425

Query: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199
            Y +   C     P  C  +   V    + ++GCY C     F  E+G CV     PC   
Sbjct: 426  YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 478

Query: 1200 TTPQPP 1205
             T  PP
Sbjct: 479  GTLYPP 484



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%)

Query: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568
            SQ   + S  +   S  S  + TH P +TP +  T   NP  T T  PV     + T+ +
Sbjct: 1483 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1542

Query: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628
             P   T    P G +   ++  +TA+      T P  S     L T  P   +  +  + 
Sbjct: 1543 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1601

Query: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS---THTAPTMTLTTSGTSQAL 1682
             TVI      +  S+   S P    P  T   T++  GS     T P  +LT S +S+ +
Sbjct: 1602 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPV 1659

Query: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737
            +S    +++ TS  SH +    A     S T + P PT   S  +P   +T +GT+  + 
Sbjct: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1718

Query: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
              S  +T      L +      H +    S  S  P+   +    P  HTT AT S    
Sbjct: 1719 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1777

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850
            P T    P   +  ++T  + AT F +  +T P+       P T+LP      S  + TP
Sbjct: 1778 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1833

Query: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908
                 +I T  Q   +    ++P  T+ P  P T  A    H    + P  +GT+     
Sbjct: 1834 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1889

Query: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968
             +T  TS  LP    +         S  ++ P+ ++TG    ++   S     LPT    
Sbjct: 1890 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1934

Query: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024
                 GS+    T    ATS   T     P   Q  T LP    P S +L   S  T   
Sbjct: 1935 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1987

Query: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082
              ++    Q+A +    + P     P        S  +AP +++   G ++  ++ + A 
Sbjct: 1988 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 2046

Query: 2083 ASSSFI 2088
             S++ +
Sbjct: 2047 TSTTCV 2052



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%)

Query: 344  DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388
            + + + TCVP+ +  CV H  +     + +   Q C       RC +        G   C
Sbjct: 2044 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2102

Query: 389  TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446
                C   CS+       TFD           YIL QSP   ++   + V D   + + H
Sbjct: 2103 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2159

Query: 447  SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502
                   +V L+      ++ I + +  VT + +  W P       +  + + H+ M  +
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2217

Query: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559
                 +  L       V      + Q  GLCG  +GD  +D T   G   G A   + F+
Sbjct: 2218 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2277

Query: 560  DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611
            DSW+             P S++ + +       CA T CS  LR  +   F  CH  V P
Sbjct: 2278 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2325

Query: 612  APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671
              F +  +      ++     C AL  YV  C    V +  WR S D C   C+ ++T+ 
Sbjct: 2326 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2379

Query: 672  YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726
                ACE  +TC        +  H  V  +GC C +GT L+++    C+ +A+C C    
Sbjct: 2380 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2439

Query: 727  GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
            G    L E     N     C   +   P         C +P+  +SC +  E    A   
Sbjct: 2440 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2492

Query: 787  PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830
            PT      G  CV   T CE   P C     L  +  +  C P   C C+
Sbjct: 2493 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2542



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 174/731 (23%), Positives = 248/731 (33%), Gaps = 102/731 (13%)

Query: 1153 CTWHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP-CMPPTTPQPPTTPQLP 1211
            C W Y  C  P   Q+        C +  +          CVP C  P      T   + 
Sbjct: 1408 CEWRYDACASPCF-QTCRDPRAASCRDVPRGRS-------CVPVCPTPQVLDEVTQRCVY 1459

Query: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTG-PSPS------SNHTPASPTQTPLLPATLTSSKP 1264
                    VW  T       L  S G P+PS      S  +P +PT  P     LT + P
Sbjct: 1460 LEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP----ALTPAAP 1515

Query: 1265 TASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQST 1324
              ++  PP  T    P  + G  PT T      + T +Q     T S AS   T++  + 
Sbjct: 1516 LTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572

Query: 1325 TRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPT 1384
              T  +   P    T      S   E    T      P  T +S    + P P  P    
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAPRFPLMTK 1629

Query: 1385 ATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLP 1444
            A       +    TTP  P  T SP  +  PV S G ++ +        PT S       
Sbjct: 1630 AVTVRGHGSLPVRTTPPQPSLTASP--SSRPVASPGAISRS--------PTSSGSH---- 1675

Query: 1445 THVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504
                    +++TP+   VI+ T     T A + S+P+      T L   G+     P++P
Sbjct: 1676 -------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAAEQVPVSP 1722

Query: 1505 TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSA 1564
                T       ST K     HS       P  +P S     P+P  +    P  HT  A
Sbjct: 1723 L--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRPAQHTTMA 1770

Query: 1565 TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTLPTHVPPF 1619
            T S   PP T    P  +S  ++T  + AT F +  +T P+       P T+LP      
Sbjct: 1771 TRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGT 1826

Query: 1620 STSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSG 1677
            S  + T  P    + TP   Q  T  +    P     P    +A   TH AP      +G
Sbjct: 1827 SAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP----PAAG 1882

Query: 1678 TSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSR 1737
            T+  L    T  TS  L         AE T+ S  ++ P  ++TG   + + +   S   
Sbjct: 1883 TAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILSKQVSLPT 1932

Query: 1738 SSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSS 1791
            S + +A+      T  + H  T     PE     T    P  TS       A T    S 
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSARTAPQDSM 1990

Query: 1792 RLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS 1851
             +  P    +  T   P  +  PV     + TT     S P  ++   +     +    +
Sbjct: 1991 LVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEALATTTEAN 2046

Query: 1852 THTVIIPTHTQ 1862
            T T  +P   Q
Sbjct: 2047 TSTTCVPIAEQ 2057



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98
            P    C+ +G  H+ TFD   +DF G C  ++  +T   +F      +     G I R  
Sbjct: 980  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 1039

Query: 99   VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +      + V  ++I   D      P  +  +  ++  +      +    +  + ++W  
Sbjct: 1040 IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1094

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209
             + + V    ++ GQ+ GLCGNFD K  NE  + E  +   P +F    AA++  D  DP
Sbjct: 1095 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1154

Query: 210  GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267
             ++C    +     R+    + C+ LL+ V   C   V    F  +C  D     Q G  
Sbjct: 1155 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209

Query: 268  NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297
               CA++S Y+ QC   G  V  WR+P LC
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1238



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 124/521 (23%), Positives = 202/521 (38%), Gaps = 76/521 (14%)

Query: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931
            T+PP    PT            P TPT       P+    A  +T+L    ++T  P V+
Sbjct: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1533

Query: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985
            P  T T +      T ++ P   T S +S  +        H+P + S P +   P   M 
Sbjct: 1534 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1593

Query: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
            + + +TT  T      P  T+ +  PP                  T+  T     S P  
Sbjct: 1594 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1642

Query: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS---SS 2100
            T PP  +L A+ S+   A P  ++ S TS + S  +  T + + + S + +PQ +   S+
Sbjct: 1643 TTPPQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1701

Query: 2101 RPPSSPITT------QLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143
              PS+P+T       Q+P            LS+       +  + S  SP P  P   + 
Sbjct: 1702 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1760

Query: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
              P+ H++  T SP          S+ T++  ++A    +  S+     LS  P   S+ 
Sbjct: 1761 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1820

Query: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245
             + +  S+P A+   +A++  T   P        TLS +LP +   ++   P +H+A   
Sbjct: 1821 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1880

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
                      A+  T+        T+   S+  R  T+G V++ S    +PTS      +
Sbjct: 1881 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1937

Query: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
               GPT L+P T    + L A    P  A   +   P PTS
Sbjct: 1938 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1974



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%)

Query: 117  DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175
            D+  +  P +  G +I   G    ++      ++++ W   S LM++   K    Q  GL
Sbjct: 2191 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2247

Query: 176  CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228
            CG  DG   N+   ++G        + +   +DP        +PS  T V Q +      
Sbjct: 2248 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2299

Query: 229  -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281
                C+  L +V      A    V  E F      D     QP      C  L+ Y   C
Sbjct: 2300 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2353

Query: 282  SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332
                  +  WR    C    C ++  YQ C +AC   KTC        +P+H        
Sbjct: 2354 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2409

Query: 333  GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379
            GC C EGT+L+   ++  C+P  +C C    G   A GE   ++   C
Sbjct: 2410 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%)

Query: 794  TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847
            T   CVP   E  CV   C EG L      Q  P    P  C   G++   G +      
Sbjct: 2047 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2105

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
             C+C                C+++ +   +TFDG          YIL         SQ  
Sbjct: 2106 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2141

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967
             ++LT +V+       C  A    L      L   N T      H+   VT    +  V 
Sbjct: 2142 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2189

Query: 968  ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003
            + +        RY   +    HM                   +++  ++ S+    GLCG
Sbjct: 2190 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2249

Query: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057
              +G+  +D   +   V   A      ++SW+        G   F  D C         A
Sbjct: 2250 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2300

Query: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113
               CS    +++++TF+ CH  V    + E  +RD             C A+  Y   C 
Sbjct: 2301 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2354

Query: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137
               VC++WR   +CP  C   +T+
Sbjct: 2355 KFHVCIEWRRSDYCPFLCSSDSTY 2378



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 58/270 (21%), Positives = 106/270 (39%), Gaps = 22/270 (8%)

Query: 2088 ISSSSWLPQNS---SSRPPSSPITT---QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV 2141
            +  + W+P  +    + PPS  + T   + P LS  +    T        + +P+AP T 
Sbjct: 1464 VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP-----ALTPAAPLTT 1518

Query: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT--LSSGSHSSLSTHPTTASVSASPLFP 2199
            +   P + +     SP  G + + +  P+  T   L +G   S ++   TAS+ A P  P
Sbjct: 1519 ALNPPVTATEEPVVSP--GPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1576

Query: 2200 SSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259
             S +    ++   P  +S     + +    TV  + +P+  ++S +   P  P  T +  
Sbjct: 1577 ESSSLPVALQTPTPGMVSGAMETTRV----TVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632

Query: 2260 TAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFL 2319
                 S    T+      T  P+S  V+    ++  PTS  ++     P  T   +   +
Sbjct: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692

Query: 2320 TSSLTAHGSTPASAPVSSLGT---PTPTSP 2346
                 A  ++  S P++  GT     P SP
Sbjct: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSP 1722



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
            V +  C+G C SA+ +N         C CCR +    + ++L C   +T    +  T+Q 
Sbjct: 2859 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2915

Query: 2427 FSHCVC 2432
             + C C
Sbjct: 2916 PTDCAC 2921


>gi|239749989 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  512 bits (1318), Expect = e-144
 Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104
            C  WG  H  TFD   Y  SG  +Y      +    +FS+Q+   P    S        S
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138

Query: 105  VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159
            +  V E  I + K++   G+ + LP+     ++    Q    V  + +    + W   S 
Sbjct: 139  LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 195

Query: 160  LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214
            + + +  + +G   GLCGN +    ++ V+  GK  +      H +        PG   T
Sbjct: 196  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 253

Query: 215  FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266
               +P     Q     +      C  LL      C   VS  PF  SC +D+  +   G 
Sbjct: 254  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 311

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325
              + C  L+EY+R C+  G+P++ WR+    C+V        Y EC + C  +C +P+ S
Sbjct: 312  VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 370

Query: 326  CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
            C  S   C  GC+CP G +  D      CV   +CPC  HG +Y PG V    C TC CT
Sbjct: 371  CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 426

Query: 383  LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442
             G+W C+   CP  CS+ G    TTFD R Y F  TC YIL +S      G        +
Sbjct: 427  SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 483

Query: 443  --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496
              G++     + +V  +  QD   ++ ++Q   V    + K +P Y      + R +S  
Sbjct: 484  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 543

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L++ T+ G+ ++   R   + Y+ V  ++   T GLCG FNG+T DDF + +G+ E T  
Sbjct: 544  LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 557  LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614
            LF +SW+  +   P       DPC +       +   CS+L  TG +F  C A ++P P+
Sbjct: 603  LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 660

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
            +++C   AC   +  P +CA L  Y H C   G+ +  +R+ +  C + C  +  +S   
Sbjct: 661  FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 717

Query: 675  QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721
              C RTC  L+                EC      V+GC CP  TYL+ + + CV + QC
Sbjct: 718  APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 771

Query: 722  PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781
             C  +G  +   +      G  CHC +G +SC  R     A+C A + F +CS    +  
Sbjct: 772  SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 827

Query: 782  GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
              +   TC Q L          C  GC C +GL  + D  C  PEECPC + G  Y  G 
Sbjct: 828  ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 886

Query: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
            ++ + C TC C RG + C     C STCT YG+ H  TFDG  F F G C+  L      
Sbjct: 887  QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945

Query: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959
            V+     F ++ ENV C +SG+ C + I I +G   +V  D +   + E     +  V  
Sbjct: 946  VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1000

Query: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
              +     +  P  + +TL+W++  T+ ++     Q  L GLCGNF+    ++  T    
Sbjct: 1001 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059

Query: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079
              ++  E  +SW     C D     D C LN  R  +A+++CS++ S+ F  CH  V   
Sbjct: 1060 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1118

Query: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139
             +Y  C+ D CGC  GGDCEC C +V+AYA  C   GV VDWRTP  CP  C F+N    
Sbjct: 1119 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1177

Query: 1140 DGHGEYQYTQEA 1151
             G G YQ +  A
Sbjct: 1178 -GKGPYQLSSLA 1188



 Score =  226 bits (577), Expect = 2e-58
 Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%)

Query: 397  CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454
            C   G   V TFD   Y   G  +Y L+   +       + V++  + G S    S    
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138

Query: 455  VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514
            ++   + +I ++++  VT+ G    LP+           S  LQ    +   ++V+ +  
Sbjct: 139  LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 185

Query: 515  FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566
            F          Y+ + P+  G T GLCGN N D  DD  TS G        FV SW+   
Sbjct: 186  FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 243

Query: 567  CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625
               A  +   P + S     C + +   +     V+E+C A + P        + AC+ Y
Sbjct: 244  --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 291

Query: 626  EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685
                P                              T  CT +             C S+ 
Sbjct: 292  VSPLPF-----------------------------TASCTSDL------------CQSMG 310

Query: 686  DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745
            D AT C   A     C                 AQ    L+G++       T +   T H
Sbjct: 311  DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 346

Query: 746  CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805
            C         + + F        T+  C         A+C P    + + +ACV      
Sbjct: 347  C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 380

Query: 806  GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
            GC C  GL    DG CV P ECPCEF G  YP G+ +  DC TC+C+ G+W C     CP
Sbjct: 381  GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 438

Query: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924
            + C++ G+ H  TFDG+R+ F   C+YILA      + S  TF +  +N  CG N    C
Sbjct: 439  AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 493

Query: 925  SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977
             +++ + L       V L      +  ++  +    T  A  +     V + +     + 
Sbjct: 494  VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 553

Query: 978  LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036
            ++++R  + + +++ +   +   GLCG FNGN +DDF +      S+     NSWK    
Sbjct: 554  VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 613

Query: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094
            C  +      DPC ++    S++ + CSV+  + FA C + +  +PY+E C RDAC C  
Sbjct: 614  CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 673

Query: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152
                 CLC  +A YA  C   G+ VD+R   PA C + C                     
Sbjct: 674  ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 708

Query: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195
             +  Y PC+ P        + P++  V G +       +EGC  C  D Y D +  +CVP
Sbjct: 709  ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 767

Query: 1196 -----CMPPTTPQPPTTPQLPTTG 1214
                 C       PP    +P+ G
Sbjct: 768  RNQCSCHFQGVDYPPGDSDIPSLG 791



 Score =  118 bits (295), Expect = 8e-26
 Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%)

Query: 38  TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92
           TA    +CS  G  HF+TFD   Y F  TC YI A +      TF+V L+  P G     
Sbjct: 434 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 491

Query: 93  ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147
               S+S I+ +     VT+++A  + + D   I  PYT +  +I     S   +  +  
Sbjct: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 549

Query: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205
           + + V++  +   L + V+++++    GLCG F+G   ++F+S  G     P  F    K
Sbjct: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609

Query: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259
                 P    +  D    H++ A ++ + C+ L   +   CS  +S  P+   C+ D  
Sbjct: 610 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669

Query: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318
              QP      CATL+ Y+  C   G PV  R R P  C++  C A++ Y  C + C +T
Sbjct: 670 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 723

Query: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
           C +     +C            C  GC CP  T L+  ++   CVP  QC C   G  Y 
Sbjct: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 781

Query: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409
           PG+  I +   C C  G   C  R  P      G  FV   D
Sbjct: 782 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 822



 Score =  111 bits (277), Expect = 1e-23
 Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%)

Query: 802  KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859
            KC P  +  C  G      G+CV P  C C     + P               R +    
Sbjct: 32   KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 70

Query: 860  QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917
             G    S C  +G+ HV TFDG  +   G   Y L     G ++ +  +F I   N   C
Sbjct: 71   AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 126

Query: 918  GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974
            G+S  TCSRA+ +F  G   +   +  T  G   + PHV        L+  V +     +
Sbjct: 127  GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 186

Query: 975  NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034
              TL W+    + I+++        GLCGN N + KDD  T S  +    +E V+SW+E 
Sbjct: 187  --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 244

Query: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088
                 P     S    PC   N         +C  +    F  CH+ V  LP+  +C  D
Sbjct: 245  APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 304

Query: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146
               C S GD    C A+A YA+AC   G  +  WRT    C ++C             + 
Sbjct: 305  L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 353

Query: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199
            Y +   C     P  C  +   V    + ++GCY C     F  E+G CV     PC   
Sbjct: 354  YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 406

Query: 1200 TTPQPP 1205
             T  PP
Sbjct: 407  GTLYPP 412



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 176/738 (23%), Positives = 253/738 (34%), Gaps = 116/738 (15%)

Query: 1153 CTWHYQPCLCP----------SQPQSVPGSNIEGCYN-CSQDEYFDHEEGVCV---PCMP 1198
            C W Y  C  P          +  + VP   +EGC   C   +  D     CV    C+ 
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVP--RVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393

Query: 1199 PTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPS-SNHTPASPTQTPLLPA 1257
            P    P  T  L      P+Q           GL + +   P  S  +P +PT  P    
Sbjct: 1394 PAVWVP--TEALGNETLPPSQ-----------GLPTPSDEEPQLSQESPRTPTHRP---- 1436

Query: 1258 TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPAT 1317
             LT + P  ++  PP  T    P  + G  PT T      + T +Q     T S AS   
Sbjct: 1437 ALTPAAPLTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGV 1493

Query: 1318 TSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQP 1377
            T++  +   T  +   P    T      S   E    T      P  T +S    + P P
Sbjct: 1494 TASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAP 1550

Query: 1378 GQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPS 1437
              P    A       +    TTP  P  T SP  +  PV S G ++ +        PT S
Sbjct: 1551 RFPLMTKAVTVRGHGSLPVRTTPLQPSLTASP--SSRPVASPGAISRS--------PTSS 1600

Query: 1438 HPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTH 1497
                           +++TP+   VI+ T     T A + S+P+      T L   G+  
Sbjct: 1601 GSH-----------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAA 1643

Query: 1498 TAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTP 1557
               P++P    T       ST K     HS       P  +P S     P+P  +    P
Sbjct: 1644 EQVPVSPL--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRP 1691

Query: 1558 VAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTL 1612
              HT  AT S   PP T    P  +S  ++T  + AT F +  +T P+       P T+L
Sbjct: 1692 AQHTTMATRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSL 1747

Query: 1613 PTHVPPFSTSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670
            P      S  + T  P    + TP   Q  T  +    P     P    +A   TH AP 
Sbjct: 1748 PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP- 1806

Query: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730
                 +GT+  L    T  TS  L         AE T+ S  ++ P  ++TG   + + +
Sbjct: 1807 ---PAAGTAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILS 1853

Query: 1731 SGTSQSRSSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAH 1784
               S   S + +A+      T  + H  T     PE     T    P  TS       A 
Sbjct: 1854 KQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSAR 1911

Query: 1785 TTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFS 1844
            T    S  +  P    +  T   P  +  PV     + TT     S P  ++   +    
Sbjct: 1912 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEAL 1967

Query: 1845 TSLVTPSTHTVIIPTHTQ 1862
             +    +T T  +P   Q
Sbjct: 1968 ATTTEANTSTTCVPIAEQ 1985



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%)

Query: 344  DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388
            + + + TCVP+ +  CV H  +     + +   Q C       RC +        G   C
Sbjct: 1972 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2030

Query: 389  TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446
                C   CS+       TFD           YIL QSP   ++   + V D   + + H
Sbjct: 2031 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2087

Query: 447  SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502
                   +V L+      ++ I + +  VT + +  W P       +  + + H+ M  +
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2145

Query: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559
                 +  L       V      + Q  GLCG  +GD  +D T   G   G A   + F+
Sbjct: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205

Query: 560  DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611
            DSW+             P S++ + +       CA T CS  LR  +   F  CH  V P
Sbjct: 2206 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2253

Query: 612  APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671
              F +  +      ++     C AL  YV  C    V +  WR S D C   C+ ++T+ 
Sbjct: 2254 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2307

Query: 672  YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726
                ACE  +TC        +  H  V  +GC C +GT L+++    C+ +A+C C    
Sbjct: 2308 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2367

Query: 727  GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
            G    L E     N     C   +   P         C +P+  +SC +  E    A   
Sbjct: 2368 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2420

Query: 787  PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830
            PT      G  CV   T CE   P C     L  +  +  C P   C C+
Sbjct: 2421 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2470



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%)

Query: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568
            SQ   + S  +   S  S  + TH P +TP +  T   NP  T T  PV     + T+ +
Sbjct: 1411 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1470

Query: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628
             P   T    P G +   ++  +TA+      T P  S     L T  P   +  +  + 
Sbjct: 1471 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1529

Query: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS--THTAPTM-TLTTSGTSQAL 1682
             TVI      +  S+   S P    P  T   T++  GS    T P   +LT S +S+ +
Sbjct: 1530 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPV 1587

Query: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737
            +S    +++ TS  SH +    A     S T + P PT   S  +P   +T +GT+  + 
Sbjct: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1646

Query: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
              S  +T      L +      H +    S  S  P+   +    P  HTT AT S    
Sbjct: 1647 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1705

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850
            P T    P   +  ++T  + AT F +  +T P+       P T+LP      S  + TP
Sbjct: 1706 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1761

Query: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908
                 +I T  Q   +    ++P  T+ P  P T  A    H    + P  +GT+     
Sbjct: 1762 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1817

Query: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968
             +T  TS  LP    +         S  ++ P+ ++TG    ++   S     LPT    
Sbjct: 1818 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1862

Query: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024
                 GS+    T    ATS   T     P   Q  T LP    P S +L   S  T   
Sbjct: 1863 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1915

Query: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082
              ++    Q+A +    + P     P        S  +AP +++   G ++  ++ + A 
Sbjct: 1916 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 1974

Query: 2083 ASSSFI 2088
             S++ +
Sbjct: 1975 TSTTCV 1980



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98
            P    C+ +G  H+ TFD   +DF G C  ++  +T   +F      +     G I R  
Sbjct: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 967

Query: 99   VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +      + V  ++I   D      P  +  +  ++  +      +    +  + ++W  
Sbjct: 968  IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1022

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209
             + + V    ++ GQ+ GLCGNFD K  NE  + E  +   P +F    AA++  D  DP
Sbjct: 1023 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1082

Query: 210  GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267
             ++C    +     R+    + C+ LL+ V   C   V    F  +C  D     Q G  
Sbjct: 1083 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137

Query: 268  NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297
               CA++S Y+ QC   G  V  WR+P LC
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 122/521 (23%), Positives = 199/521 (38%), Gaps = 76/521 (14%)

Query: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931
            T+PP    PT            P TPT       P+    A  +T+L    ++T  P V+
Sbjct: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1461

Query: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985
            P  T T +      T ++ P   T S +S  +        H+P + S P +   P   M 
Sbjct: 1462 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1521

Query: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
            + + +TT  T      P  T+ +  PP                  T+  T     S P  
Sbjct: 1522 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1570

Query: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPP 2103
            T P   +L A+ S+   A P  ++ S TS + S  +  T + + + S + +PQ + ++  
Sbjct: 1571 TTPLQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1629

Query: 2104 SSPIT---------TQLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143
            SSP T          Q+P            LS+       +  + S  SP P  P   + 
Sbjct: 1630 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1688

Query: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
              P+ H++  T SP          S+ T++  ++A    +  S+     LS  P   S+ 
Sbjct: 1689 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1748

Query: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245
             + +  S+P A+   +A++  T   P        TLS +LP +   ++   P +H+A   
Sbjct: 1749 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1808

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
                      A+  T+        T+   S+  R  T+G V++ S    +PTS      +
Sbjct: 1809 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1865

Query: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
               GPT L+P T    + L A    P  A   +   P PTS
Sbjct: 1866 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1902



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%)

Query: 117  DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175
            D+  +  P +  G +I   G    ++      ++++ W   S LM++   K    Q  GL
Sbjct: 2119 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2175

Query: 176  CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228
            CG  DG   N+   ++G        + +   +DP        +PS  T V Q +      
Sbjct: 2176 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2227

Query: 229  -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281
                C+  L +V      A    V  E F      D     QP      C  L+ Y   C
Sbjct: 2228 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2281

Query: 282  SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332
                  +  WR    C    C ++  YQ C +AC   KTC        +P+H        
Sbjct: 2282 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2337

Query: 333  GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379
            GC C EGT+L+   ++  C+P  +C C    G   A GE   ++   C
Sbjct: 2338 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%)

Query: 794  TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847
            T   CVP   E  CV   C EG L      Q  P    P  C   G++   G +      
Sbjct: 1975 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2033

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
             C+C                C+++ +   +TFDG          YIL         SQ  
Sbjct: 2034 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2069

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967
             ++LT +V+       C  A    L      L   N T      H+   VT    +  V 
Sbjct: 2070 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2117

Query: 968  ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003
            + +        RY   +    HM                   +++  ++ S+    GLCG
Sbjct: 2118 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2177

Query: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057
              +G+  +D   +   V   A      ++SW+        G   F  D C         A
Sbjct: 2178 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2228

Query: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113
               CS    +++++TF+ CH  V    + E  +RD             C A+  Y   C 
Sbjct: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2282

Query: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137
               VC++WR   +CP  C   +T+
Sbjct: 2283 KFHVCIEWRRSDYCPFLCSSDSTY 2306



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 65/276 (23%), Positives = 111/276 (40%), Gaps = 37/276 (13%)

Query: 2088 ISSSSWLPQNS---SSRPPSSPITT---QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV 2141
            +  + W+P  +    + PPS  + T   + P LS  +    T        + +P+AP T 
Sbjct: 1392 VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP-----ALTPAAPLTT 1446

Query: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT--LSSGSHSSLSTHPTTASVSASPLFP 2199
            +   P + +     SP  G + + +  P+  T   L +G   S ++   TAS+ A P  P
Sbjct: 1447 ALNPPVTATEEPVVSP--GPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504

Query: 2200 SSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259
             S +    ++   P  +S     + +    TV  + +P+  ++S +   P  PR    T 
Sbjct: 1505 ESSSLPVALQTPTPGMVSGAMETTRV----TVIFAGSPNITVSSRS---PPAPRFPLMTK 1557

Query: 2260 TAPAFSSQSTTSRSTSL---TTRVPTSGFVSLTSGVTGIPTS----------PVTNLTTR 2306
                    S   R+T L    T  P+S  V+    ++  PTS           VT + +R
Sbjct: 1558 AVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISR 1617

Query: 2307 H--PGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGT 2340
               P PT + +    ++ LT  G+     PVS L T
Sbjct: 1618 TGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLAT 1653



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
            V +  C+G C SA+ +N         C CCR +    + ++L C   +T    +  T+Q 
Sbjct: 2787 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2843

Query: 2427 FSHCVC 2432
             + C C
Sbjct: 2844 PTDCAC 2849


>gi|239749987 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  512 bits (1318), Expect = e-144
 Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104
            C  WG  H  TFD   Y  SG  +Y      +    +FS+Q+   P    S        S
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210

Query: 105  VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159
            +  V E  I + K++   G+ + LP+     ++    Q    V  + +    + W   S 
Sbjct: 211  LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 267

Query: 160  LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214
            + + +  + +G   GLCGN +    ++ V+  GK  +      H +        PG   T
Sbjct: 268  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 325

Query: 215  FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266
               +P     Q     +      C  LL      C   VS  PF  SC +D+  +   G 
Sbjct: 326  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 383

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325
              + C  L+EY+R C+  G+P++ WR+    C+V        Y EC + C  +C +P+ S
Sbjct: 384  VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 442

Query: 326  CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
            C  S   C  GC+CP G +  D      CV   +CPC  HG +Y PG V    C TC CT
Sbjct: 443  CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 498

Query: 383  LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442
             G+W C+   CP  CS+ G    TTFD R Y F  TC YIL +S      G        +
Sbjct: 499  SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 555

Query: 443  --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496
              G++     + +V  +  QD   ++ ++Q   V    + K +P Y      + R +S  
Sbjct: 556  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 615

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L++ T+ G+ ++   R   + Y+ V  ++   T GLCG FNG+T DDF + +G+ E T  
Sbjct: 616  LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 557  LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614
            LF +SW+  +   P       DPC +       +   CS+L  TG +F  C A ++P P+
Sbjct: 675  LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 732

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
            +++C   AC   +  P +CA L  Y H C   G+ +  +R+ +  C + C  +  +S   
Sbjct: 733  FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 789

Query: 675  QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721
              C RTC  L+                EC      V+GC CP  TYL+ + + CV + QC
Sbjct: 790  APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 843

Query: 722  PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781
             C  +G  +   +      G  CHC +G +SC  R     A+C A + F +CS    +  
Sbjct: 844  SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 899

Query: 782  GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
              +   TC Q L          C  GC C +GL  + D  C  PEECPC + G  Y  G 
Sbjct: 900  ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 958

Query: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
            ++ + C TC C RG + C     C STCT YG+ H  TFDG  F F G C+  L      
Sbjct: 959  QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017

Query: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959
            V+     F ++ ENV C +SG+ C + I I +G   +V  D +   + E     +  V  
Sbjct: 1018 VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1072

Query: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
              +     +  P  + +TL+W++  T+ ++     Q  L GLCGNF+    ++  T    
Sbjct: 1073 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1131

Query: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079
              ++  E  +SW     C D     D C LN  R  +A+++CS++ S+ F  CH  V   
Sbjct: 1132 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1190

Query: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139
             +Y  C+ D CGC  GGDCEC C +V+AYA  C   GV VDWRTP  CP  C F+N    
Sbjct: 1191 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1249

Query: 1140 DGHGEYQYTQEA 1151
             G G YQ +  A
Sbjct: 1250 -GKGPYQLSSLA 1260



 Score =  226 bits (577), Expect = 2e-58
 Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%)

Query: 397  CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454
            C   G   V TFD   Y   G  +Y L+   +       + V++  + G S    S    
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210

Query: 455  VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514
            ++   + +I ++++  VT+ G    LP+           S  LQ    +   ++V+ +  
Sbjct: 211  LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 257

Query: 515  FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566
            F          Y+ + P+  G T GLCGN N D  DD  TS G        FV SW+   
Sbjct: 258  FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 315

Query: 567  CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625
               A  +   P + S     C + +   +     V+E+C A + P        + AC+ Y
Sbjct: 316  --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 363

Query: 626  EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685
                P                              T  CT +             C S+ 
Sbjct: 364  VSPLPF-----------------------------TASCTSDL------------CQSMG 382

Query: 686  DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745
            D AT C   A     C                 AQ    L+G++       T +   T H
Sbjct: 383  DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 418

Query: 746  CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805
            C         + + F        T+  C         A+C P    + + +ACV      
Sbjct: 419  C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 452

Query: 806  GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
            GC C  GL    DG CV P ECPCEF G  YP G+ +  DC TC+C+ G+W C     CP
Sbjct: 453  GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 510

Query: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924
            + C++ G+ H  TFDG+R+ F   C+YILA      + S  TF +  +N  CG N    C
Sbjct: 511  AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 565

Query: 925  SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977
             +++ + L       V L      +  ++  +    T  A  +     V + +     + 
Sbjct: 566  VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 625

Query: 978  LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036
            ++++R  + + +++ +   +   GLCG FNGN +DDF +      S+     NSWK    
Sbjct: 626  VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 685

Query: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094
            C  +      DPC ++    S++ + CSV+  + FA C + +  +PY+E C RDAC C  
Sbjct: 686  CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 745

Query: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152
                 CLC  +A YA  C   G+ VD+R   PA C + C                     
Sbjct: 746  ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 780

Query: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195
             +  Y PC+ P        + P++  V G +       +EGC  C  D Y D +  +CVP
Sbjct: 781  ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 839

Query: 1196 -----CMPPTTPQPPTTPQLPTTG 1214
                 C       PP    +P+ G
Sbjct: 840  RNQCSCHFQGVDYPPGDSDIPSLG 863



 Score =  118 bits (295), Expect = 8e-26
 Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%)

Query: 38  TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92
           TA    +CS  G  HF+TFD   Y F  TC YI A +      TF+V L+  P G     
Sbjct: 506 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 563

Query: 93  ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147
               S+S I+ +     VT+++A  + + D   I  PYT +  +I     S   +  +  
Sbjct: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 621

Query: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205
           + + V++  +   L + V+++++    GLCG F+G   ++F+S  G     P  F    K
Sbjct: 622 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 681

Query: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259
                 P    +  D    H++ A ++ + C+ L   +   CS  +S  P+   C+ D  
Sbjct: 682 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741

Query: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318
              QP      CATL+ Y+  C   G PV  R R P  C++  C A++ Y  C + C +T
Sbjct: 742 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 795

Query: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
           C +     +C            C  GC CP  T L+  ++   CVP  QC C   G  Y 
Sbjct: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 853

Query: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409
           PG+  I +   C C  G   C  R  P      G  FV   D
Sbjct: 854 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 894



 Score =  111 bits (277), Expect = 1e-23
 Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%)

Query: 802  KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859
            KC P  +  C  G      G+CV P  C C     + P               R +    
Sbjct: 104  KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 142

Query: 860  QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917
             G    S C  +G+ HV TFDG  +   G   Y L     G ++ +  +F I   N   C
Sbjct: 143  AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 198

Query: 918  GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974
            G+S  TCSRA+ +F  G   +   +  T  G   + PHV        L+  V +     +
Sbjct: 199  GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 258

Query: 975  NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034
              TL W+    + I+++        GLCGN N + KDD  T S  +    +E V+SW+E 
Sbjct: 259  --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 316

Query: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088
                 P     S    PC   N         +C  +    F  CH+ V  LP+  +C  D
Sbjct: 317  APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 376

Query: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146
               C S GD    C A+A YA+AC   G  +  WRT    C ++C             + 
Sbjct: 377  L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 425

Query: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199
            Y +   C     P  C  +   V    + ++GCY C     F  E+G CV     PC   
Sbjct: 426  YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 478

Query: 1200 TTPQPP 1205
             T  PP
Sbjct: 479  GTLYPP 484



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%)

Query: 344  DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388
            + + + TCVP+ +  CV H  +     + +   Q C       RC +        G   C
Sbjct: 2044 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2102

Query: 389  TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446
                C   CS+       TFD           YIL QSP   ++   + V D   + + H
Sbjct: 2103 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2159

Query: 447  SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502
                   +V L+      ++ I + +  VT + +  W P       +  + + H+ M  +
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2217

Query: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559
                 +  L       V      + Q  GLCG  +GD  +D T   G   G A   + F+
Sbjct: 2218 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2277

Query: 560  DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611
            DSW+             P S++ + +       CA T CS  LR  +   F  CH  V P
Sbjct: 2278 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2325

Query: 612  APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671
              F +  +      ++     C AL  YV  C    V +  WR S D C   C+ ++T+ 
Sbjct: 2326 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2379

Query: 672  YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726
                ACE  +TC        +  H  V  +GC C +GT L+++    C+ +A+C C    
Sbjct: 2380 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2439

Query: 727  GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
            G    L E     N     C   +   P         C +P+  +SC +  E    A   
Sbjct: 2440 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2492

Query: 787  PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830
            PT      G  CV   T CE   P C     L  +  +  C P   C C+
Sbjct: 2493 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2542



 Score = 92.4 bits (228), Expect = 5e-18
 Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%)

Query: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568
            SQ   + S  +   S  S  + TH P +TP +  T   NP  T T  PV     + T+ +
Sbjct: 1483 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1542

Query: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628
             P   T    P G +   ++  +TA+      T P  S     L T  P   +  +  + 
Sbjct: 1543 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1601

Query: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS--THTAPTM-TLTTSGTSQAL 1682
             TVI      +  S+   S P    P  T   T++  GS    T P   +LT S +S+ +
Sbjct: 1602 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPLQPSLTASPSSRPV 1659

Query: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737
            +S    +++ TS  SH +    A     S T + P PT   S  +P   +T +GT+  + 
Sbjct: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1718

Query: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
              S  +T      L +      H +    S  S  P+   +    P  HTT AT S    
Sbjct: 1719 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1777

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850
            P T    P   +  ++T  + AT F +  +T P+       P T+LP      S  + TP
Sbjct: 1778 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1833

Query: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908
                 +I T  Q   +    ++P  T+ P  P T  A    H    + P  +GT+     
Sbjct: 1834 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1889

Query: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968
             +T  TS  LP    +         S  ++ P+ ++TG    ++   S     LPT    
Sbjct: 1890 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1934

Query: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024
                 GS+    T    ATS   T     P   Q  T LP    P S +L   S  T   
Sbjct: 1935 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1987

Query: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082
              ++    Q+A +    + P     P        S  +AP +++   G ++  ++ + A 
Sbjct: 1988 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 2046

Query: 2083 ASSSFI 2088
             S++ +
Sbjct: 2047 TSTTCV 2052



 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 174/731 (23%), Positives = 248/731 (33%), Gaps = 102/731 (13%)

Query: 1153 CTWHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP-CMPPTTPQPPTTPQLP 1211
            C W Y  C  P   Q+        C +  +          CVP C  P      T   + 
Sbjct: 1408 CEWRYDACASPCF-QTCRDPRAASCRDVPRGRS-------CVPVCPTPQVLDEVTQRCVY 1459

Query: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTG-PSPS------SNHTPASPTQTPLLPATLTSSKP 1264
                    VW  T       L  S G P+PS      S  +P +PT  P     LT + P
Sbjct: 1460 LEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP----ALTPAAP 1515

Query: 1265 TASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQST 1324
              ++  PP  T    P  + G  PT T      + T +Q     T S AS   T++  + 
Sbjct: 1516 LTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572

Query: 1325 TRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPT 1384
              T  +   P    T      S   E    T      P  T +S    + P P  P    
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAPRFPLMTK 1629

Query: 1385 ATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLP 1444
            A       +    TTP  P  T SP  +  PV S G ++ +        PT S       
Sbjct: 1630 AVTVRGHGSLPVRTTPLQPSLTASP--SSRPVASPGAISRS--------PTSSGSH---- 1675

Query: 1445 THVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504
                    +++TP+   VI+ T     T A + S+P+      T L   G+     P++P
Sbjct: 1676 -------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAAEQVPVSP 1722

Query: 1505 TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSA 1564
                T       ST K     HS       P  +P S     P+P  +    P  HT  A
Sbjct: 1723 L--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRPAQHTTMA 1770

Query: 1565 TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTLPTHVPPF 1619
            T S   PP T    P  +S  ++T  + AT F +  +T P+       P T+LP      
Sbjct: 1771 TRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGT 1826

Query: 1620 STSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSG 1677
            S  + T  P    + TP   Q  T  +    P     P    +A   TH AP      +G
Sbjct: 1827 SAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP----PAAG 1882

Query: 1678 TSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSR 1737
            T+  L    T  TS  L         AE T+ S  ++ P  ++TG   + + +   S   
Sbjct: 1883 TAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILSKQVSLPT 1932

Query: 1738 SSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSS 1791
            S + +A+      T  + H  T     PE     T    P  TS       A T    S 
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSARTAPQDSM 1990

Query: 1792 RLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS 1851
             +  P    +  T   P  +  PV     + TT     S P  ++   +     +    +
Sbjct: 1991 LVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEALATTTEAN 2046

Query: 1852 THTVIIPTHTQ 1862
            T T  +P   Q
Sbjct: 2047 TSTTCVPIAEQ 2057



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98
            P    C+ +G  H+ TFD   +DF G C  ++  +T   +F      +     G I R  
Sbjct: 980  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 1039

Query: 99   VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +      + V  ++I   D      P  +  +  ++  +      +    +  + ++W  
Sbjct: 1040 IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1094

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209
             + + V    ++ GQ+ GLCGNFD K  NE  + E  +   P +F    AA++  D  DP
Sbjct: 1095 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1154

Query: 210  GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267
             ++C    +     R+    + C+ LL+ V   C   V    F  +C  D     Q G  
Sbjct: 1155 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209

Query: 268  NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297
               CA++S Y+ QC   G  V  WR+P LC
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1238



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 122/521 (23%), Positives = 199/521 (38%), Gaps = 76/521 (14%)

Query: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931
            T+PP    PT            P TPT       P+    A  +T+L    ++T  P V+
Sbjct: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1533

Query: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985
            P  T T +      T ++ P   T S +S  +        H+P + S P +   P   M 
Sbjct: 1534 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1593

Query: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
            + + +TT  T      P  T+ +  PP                  T+  T     S P  
Sbjct: 1594 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1642

Query: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPP 2103
            T P   +L A+ S+   A P  ++ S TS + S  +  T + + + S + +PQ + ++  
Sbjct: 1643 TTPLQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1701

Query: 2104 SSPIT---------TQLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143
            SSP T          Q+P            LS+       +  + S  SP P  P   + 
Sbjct: 1702 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1760

Query: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
              P+ H++  T SP          S+ T++  ++A    +  S+     LS  P   S+ 
Sbjct: 1761 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1820

Query: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245
             + +  S+P A+   +A++  T   P        TLS +LP +   ++   P +H+A   
Sbjct: 1821 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1880

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
                      A+  T+        T+   S+  R  T+G V++ S    +PTS      +
Sbjct: 1881 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1937

Query: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
               GPT L+P T    + L A    P  A   +   P PTS
Sbjct: 1938 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1974



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%)

Query: 117  DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175
            D+  +  P +  G +I   G    ++      ++++ W   S LM++   K    Q  GL
Sbjct: 2191 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2247

Query: 176  CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228
            CG  DG   N+   ++G        + +   +DP        +PS  T V Q +      
Sbjct: 2248 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2299

Query: 229  -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281
                C+  L +V      A    V  E F      D     QP      C  L+ Y   C
Sbjct: 2300 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2353

Query: 282  SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332
                  +  WR    C    C ++  YQ C +AC   KTC        +P+H        
Sbjct: 2354 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2409

Query: 333  GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379
            GC C EGT+L+   ++  C+P  +C C    G   A GE   ++   C
Sbjct: 2410 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%)

Query: 794  TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847
            T   CVP   E  CV   C EG L      Q  P    P  C   G++   G +      
Sbjct: 2047 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2105

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
             C+C                C+++ +   +TFDG          YIL         SQ  
Sbjct: 2106 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2141

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967
             ++LT +V+       C  A    L      L   N T      H+   VT    +  V 
Sbjct: 2142 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2189

Query: 968  ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003
            + +        RY   +    HM                   +++  ++ S+    GLCG
Sbjct: 2190 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2249

Query: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057
              +G+  +D   +   V   A      ++SW+        G   F  D C         A
Sbjct: 2250 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2300

Query: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113
               CS    +++++TF+ CH  V    + E  +RD             C A+  Y   C 
Sbjct: 2301 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2354

Query: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137
               VC++WR   +CP  C   +T+
Sbjct: 2355 KFHVCIEWRRSDYCPFLCSSDSTY 2378



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 65/276 (23%), Positives = 111/276 (40%), Gaps = 37/276 (13%)

Query: 2088 ISSSSWLPQNS---SSRPPSSPITT---QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV 2141
            +  + W+P  +    + PPS  + T   + P LS  +    T        + +P+AP T 
Sbjct: 1464 VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP-----ALTPAAPLTT 1518

Query: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT--LSSGSHSSLSTHPTTASVSASPLFP 2199
            +   P + +     SP  G + + +  P+  T   L +G   S ++   TAS+ A P  P
Sbjct: 1519 ALNPPVTATEEPVVSP--GPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1576

Query: 2200 SSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259
             S +    ++   P  +S     + +    TV  + +P+  ++S +   P  PR    T 
Sbjct: 1577 ESSSLPVALQTPTPGMVSGAMETTRV----TVIFAGSPNITVSSRS---PPAPRFPLMTK 1629

Query: 2260 TAPAFSSQSTTSRSTSL---TTRVPTSGFVSLTSGVTGIPTS----------PVTNLTTR 2306
                    S   R+T L    T  P+S  V+    ++  PTS           VT + +R
Sbjct: 1630 AVTVRGHGSLPVRTTPLQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISR 1689

Query: 2307 H--PGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGT 2340
               P PT + +    ++ LT  G+     PVS L T
Sbjct: 1690 TGVPQPTQAQSASSPSTPLTVAGTAAEQVPVSPLAT 1725



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
            V +  C+G C SA+ +N         C CCR +    + ++L C   +T    +  T+Q 
Sbjct: 2859 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2915

Query: 2427 FSHCVC 2432
             + C C
Sbjct: 2916 PTDCAC 2921


>gi|239744300 PREDICTED: otogelin isoform 2 [Homo sapiens]
          Length = 2852

 Score =  512 bits (1318), Expect = e-144
 Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104
            C  WG  H  TFD   Y  SG  +Y      +    +FS+Q+   P    S        S
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138

Query: 105  VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159
            +  V E  I + K++   G+ + LP+     ++    Q    V  + +    + W   S 
Sbjct: 139  LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 195

Query: 160  LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214
            + + +  + +G   GLCGN +    ++ V+  GK  +      H +        PG   T
Sbjct: 196  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 253

Query: 215  FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266
               +P     Q     +      C  LL      C   VS  PF  SC +D+  +   G 
Sbjct: 254  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 311

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325
              + C  L+EY+R C+  G+P++ WR+    C+V        Y EC + C  +C +P+ S
Sbjct: 312  VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 370

Query: 326  CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
            C  S   C  GC+CP G +  D      CV   +CPC  HG +Y PG V    C TC CT
Sbjct: 371  CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 426

Query: 383  LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442
             G+W C+   CP  CS+ G    TTFD R Y F  TC YIL +S      G        +
Sbjct: 427  SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 483

Query: 443  --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496
              G++     + +V  +  QD   ++ ++Q   V    + K +P Y      + R +S  
Sbjct: 484  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 543

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L++ T+ G+ ++   R   + Y+ V  ++   T GLCG FNG+T DDF + +G+ E T  
Sbjct: 544  LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 602

Query: 557  LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614
            LF +SW+  +   P       DPC +       +   CS+L  TG +F  C A ++P P+
Sbjct: 603  LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 660

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
            +++C   AC   +  P +CA L  Y H C   G+ +  +R+ +  C + C  +  +S   
Sbjct: 661  FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 717

Query: 675  QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721
              C RTC  L+                EC      V+GC CP  TYL+ + + CV + QC
Sbjct: 718  APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 771

Query: 722  PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781
             C  +G  +   +      G  CHC +G +SC  R     A+C A + F +CS    +  
Sbjct: 772  SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 827

Query: 782  GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
              +   TC Q L          C  GC C +GL  + D  C  PEECPC + G  Y  G 
Sbjct: 828  ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 886

Query: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
            ++ + C TC C RG + C     C STCT YG+ H  TFDG  F F G C+  L      
Sbjct: 887  QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 945

Query: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959
            V+     F ++ ENV C +SG+ C + I I +G   +V  D +   + E     +  V  
Sbjct: 946  VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1000

Query: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
              +     +  P  + +TL+W++  T+ ++     Q  L GLCGNF+    ++  T    
Sbjct: 1001 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1059

Query: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079
              ++  E  +SW     C D     D C LN  R  +A+++CS++ S+ F  CH  V   
Sbjct: 1060 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1118

Query: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139
             +Y  C+ D CGC  GGDCEC C +V+AYA  C   GV VDWRTP  CP  C F+N    
Sbjct: 1119 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1177

Query: 1140 DGHGEYQYTQEA 1151
             G G YQ +  A
Sbjct: 1178 -GKGPYQLSSLA 1188



 Score =  226 bits (577), Expect = 2e-58
 Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%)

Query: 397  CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454
            C   G   V TFD   Y   G  +Y L+   +       + V++  + G S    S    
Sbjct: 79   CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 138

Query: 455  VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514
            ++   + +I ++++  VT+ G    LP+           S  LQ    +   ++V+ +  
Sbjct: 139  LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 185

Query: 515  FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566
            F          Y+ + P+  G T GLCGN N D  DD  TS G        FV SW+   
Sbjct: 186  FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 243

Query: 567  CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625
               A  +   P + S     C + +   +     V+E+C A + P        + AC+ Y
Sbjct: 244  --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 291

Query: 626  EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685
                P                              T  CT +             C S+ 
Sbjct: 292  VSPLPF-----------------------------TASCTSDL------------CQSMG 310

Query: 686  DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745
            D AT C   A     C                 AQ    L+G++       T +   T H
Sbjct: 311  DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 346

Query: 746  CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805
            C         + + F        T+  C         A+C P    + + +ACV      
Sbjct: 347  C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 380

Query: 806  GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
            GC C  GL    DG CV P ECPCEF G  YP G+ +  DC TC+C+ G+W C     CP
Sbjct: 381  GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 438

Query: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924
            + C++ G+ H  TFDG+R+ F   C+YILA      + S  TF +  +N  CG N    C
Sbjct: 439  AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 493

Query: 925  SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977
             +++ + L       V L      +  ++  +    T  A  +     V + +     + 
Sbjct: 494  VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 553

Query: 978  LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036
            ++++R  + + +++ +   +   GLCG FNGN +DDF +      S+     NSWK    
Sbjct: 554  VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 613

Query: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094
            C  +      DPC ++    S++ + CSV+  + FA C + +  +PY+E C RDAC C  
Sbjct: 614  CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 673

Query: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152
                 CLC  +A YA  C   G+ VD+R   PA C + C                     
Sbjct: 674  ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 708

Query: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195
             +  Y PC+ P        + P++  V G +       +EGC  C  D Y D +  +CVP
Sbjct: 709  ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 767

Query: 1196 -----CMPPTTPQPPTTPQLPTTG 1214
                 C       PP    +P+ G
Sbjct: 768  RNQCSCHFQGVDYPPGDSDIPSLG 791



 Score =  118 bits (295), Expect = 8e-26
 Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%)

Query: 38  TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92
           TA    +CS  G  HF+TFD   Y F  TC YI A +      TF+V L+  P G     
Sbjct: 434 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 491

Query: 93  ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147
               S+S I+ +     VT+++A  + + D   I  PYT +  +I     S   +  +  
Sbjct: 492 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 549

Query: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205
           + + V++  +   L + V+++++    GLCG F+G   ++F+S  G     P  F    K
Sbjct: 550 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 609

Query: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259
                 P    +  D    H++ A ++ + C+ L   +   CS  +S  P+   C+ D  
Sbjct: 610 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 669

Query: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318
              QP      CATL+ Y+  C   G PV  R R P  C++  C A++ Y  C + C +T
Sbjct: 670 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 723

Query: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
           C +     +C            C  GC CP  T L+  ++   CVP  QC C   G  Y 
Sbjct: 724 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 781

Query: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409
           PG+  I +   C C  G   C  R  P      G  FV   D
Sbjct: 782 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 822



 Score =  111 bits (277), Expect = 1e-23
 Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%)

Query: 802  KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859
            KC P  +  C  G      G+CV P  C C     + P               R +    
Sbjct: 32   KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 70

Query: 860  QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917
             G    S C  +G+ HV TFDG  +   G   Y L     G ++ +  +F I   N   C
Sbjct: 71   AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 126

Query: 918  GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974
            G+S  TCSRA+ +F  G   +   +  T  G   + PHV        L+  V +     +
Sbjct: 127  GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 186

Query: 975  NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034
              TL W+    + I+++        GLCGN N + KDD  T S  +    +E V+SW+E 
Sbjct: 187  --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 244

Query: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088
                 P     S    PC   N         +C  +    F  CH+ V  LP+  +C  D
Sbjct: 245  APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 304

Query: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146
               C S GD    C A+A YA+AC   G  +  WRT    C ++C             + 
Sbjct: 305  L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 353

Query: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199
            Y +   C     P  C  +   V    + ++GCY C     F  E+G CV     PC   
Sbjct: 354  YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 406

Query: 1200 TTPQPP 1205
             T  PP
Sbjct: 407  GTLYPP 412



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 176/738 (23%), Positives = 253/738 (34%), Gaps = 116/738 (15%)

Query: 1153 CTWHYQPCLCP----------SQPQSVPGSNIEGCYN-CSQDEYFDHEEGVCV---PCMP 1198
            C W Y  C  P          +  + VP   +EGC   C   +  D     CV    C+ 
Sbjct: 1336 CEWRYDACASPCFQTCRDPRAASCRDVP--RVEGCVPVCPTPQVLDEVTQRCVYLEDCVE 1393

Query: 1199 PTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPS-SNHTPASPTQTPLLPA 1257
            P    P  T  L      P+Q           GL + +   P  S  +P +PT  P    
Sbjct: 1394 PAVWVP--TEALGNETLPPSQ-----------GLPTPSDEEPQLSQESPRTPTHRP---- 1436

Query: 1258 TLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPAT 1317
             LT + P  ++  PP  T    P  + G  PT T      + T +Q     T S AS   
Sbjct: 1437 ALTPAAPLTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGV 1493

Query: 1318 TSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQP 1377
            T++  +   T  +   P    T      S   E    T      P  T +S    + P P
Sbjct: 1494 TASLLAIPHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAP 1550

Query: 1378 GQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPS 1437
              P    A       +    TTP  P  T SP  +  PV S G ++ +        PT S
Sbjct: 1551 RFPLMTKAVTVRGHGSLPVRTTPPQPSLTASP--SSRPVASPGAISRS--------PTSS 1600

Query: 1438 HPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTH 1497
                           +++TP+   VI+ T     T A + S+P+      T L   G+  
Sbjct: 1601 GSH-----------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAA 1643

Query: 1498 TAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTP 1557
               P++P    T       ST K     HS       P  +P S     P+P  +    P
Sbjct: 1644 EQVPVSPL--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRP 1691

Query: 1558 VAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTL 1612
              HT  AT S   PP T    P  +S  ++T  + AT F +  +T P+       P T+L
Sbjct: 1692 AQHTTMATRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSL 1747

Query: 1613 PTHVPPFSTSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670
            P      S  + T  P    + TP   Q  T  +    P     P    +A   TH AP 
Sbjct: 1748 PLAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP- 1806

Query: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730
                 +GT+  L    T  TS  L         AE T+ S  ++ P  ++TG   + + +
Sbjct: 1807 ---PAAGTAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILS 1853

Query: 1731 SGTSQSRSSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAH 1784
               S   S + +A+      T  + H  T     PE     T    P  TS       A 
Sbjct: 1854 KQVSLPTSMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSAR 1911

Query: 1785 TTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFS 1844
            T    S  +  P    +  T   P  +  PV     + TT     S P  ++   +    
Sbjct: 1912 TAPQDSMLVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEAL 1967

Query: 1845 TSLVTPSTHTVIIPTHTQ 1862
             +    +T T  +P   Q
Sbjct: 1968 ATTTEANTSTTCVPIAEQ 1985



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%)

Query: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568
            SQ   + S  +   S  S  + TH P +TP +  T   NP  T T  PV     + T+ +
Sbjct: 1411 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1470

Query: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628
             P   T    P G +   ++  +TA+      T P  S     L T  P   +  +  + 
Sbjct: 1471 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1529

Query: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS---THTAPTMTLTTSGTSQAL 1682
             TVI      +  S+   S P    P  T   T++  GS     T P  +LT S +S+ +
Sbjct: 1530 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPV 1587

Query: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737
            +S    +++ TS  SH +    A     S T + P PT   S  +P   +T +GT+  + 
Sbjct: 1588 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1646

Query: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
              S  +T      L +      H +    S  S  P+   +    P  HTT AT S    
Sbjct: 1647 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1705

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850
            P T    P   +  ++T  + AT F +  +T P+       P T+LP      S  + TP
Sbjct: 1706 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1761

Query: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908
                 +I T  Q   +    ++P  T+ P  P T  A    H    + P  +GT+     
Sbjct: 1762 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1817

Query: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968
             +T  TS  LP    +         S  ++ P+ ++TG    ++   S     LPT    
Sbjct: 1818 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1862

Query: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024
                 GS+    T    ATS   T     P   Q  T LP    P S +L   S  T   
Sbjct: 1863 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1915

Query: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082
              ++    Q+A +    + P     P        S  +AP +++   G ++  ++ + A 
Sbjct: 1916 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 1974

Query: 2083 ASSSFI 2088
             S++ +
Sbjct: 1975 TSTTCV 1980



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%)

Query: 344  DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388
            + + + TCVP+ +  CV H  +     + +   Q C       RC +        G   C
Sbjct: 1972 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2030

Query: 389  TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446
                C   CS+       TFD           YIL QSP   ++   + V D   + + H
Sbjct: 2031 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2087

Query: 447  SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502
                   +V L+      ++ I + +  VT + +  W P       +  + + H+ M  +
Sbjct: 2088 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2145

Query: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559
                 +  L       V      + Q  GLCG  +GD  +D T   G   G A   + F+
Sbjct: 2146 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2205

Query: 560  DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611
            DSW+             P S++ + +       CA T CS  LR  +   F  CH  V P
Sbjct: 2206 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2253

Query: 612  APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671
              F +  +      ++     C AL  YV  C    V +  WR S D C   C+ ++T+ 
Sbjct: 2254 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2307

Query: 672  YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726
                ACE  +TC        +  H  V  +GC C +GT L+++    C+ +A+C C    
Sbjct: 2308 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2367

Query: 727  GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
            G    L E     N     C   +   P         C +P+  +SC +  E    A   
Sbjct: 2368 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2420

Query: 787  PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830
            PT      G  CV   T CE   P C     L  +  +  C P   C C+
Sbjct: 2421 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2470



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98
            P    C+ +G  H+ TFD   +DF G C  ++  +T   +F      +     G I R  
Sbjct: 908  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 967

Query: 99   VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +      + V  ++I   D      P  +  +  ++  +      +    +  + ++W  
Sbjct: 968  IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1022

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209
             + + V    ++ GQ+ GLCGNFD K  NE  + E  +   P +F    AA++  D  DP
Sbjct: 1023 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1082

Query: 210  GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267
             ++C    +     R+    + C+ LL+ V   C   V    F  +C  D     Q G  
Sbjct: 1083 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1137

Query: 268  NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297
               CA++S Y+ QC   G  V  WR+P LC
Sbjct: 1138 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1166



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 124/521 (23%), Positives = 202/521 (38%), Gaps = 76/521 (14%)

Query: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931
            T+PP    PT            P TPT       P+    A  +T+L    ++T  P V+
Sbjct: 1407 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1461

Query: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985
            P  T T +      T ++ P   T S +S  +        H+P + S P +   P   M 
Sbjct: 1462 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1521

Query: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
            + + +TT  T      P  T+ +  PP                  T+  T     S P  
Sbjct: 1522 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1570

Query: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS---SS 2100
            T PP  +L A+ S+   A P  ++ S TS + S  +  T + + + S + +PQ +   S+
Sbjct: 1571 TTPPQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1629

Query: 2101 RPPSSPITT------QLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143
              PS+P+T       Q+P            LS+       +  + S  SP P  P   + 
Sbjct: 1630 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1688

Query: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
              P+ H++  T SP          S+ T++  ++A    +  S+     LS  P   S+ 
Sbjct: 1689 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1748

Query: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245
             + +  S+P A+   +A++  T   P        TLS +LP +   ++   P +H+A   
Sbjct: 1749 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1808

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
                      A+  T+        T+   S+  R  T+G V++ S    +PTS      +
Sbjct: 1809 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1865

Query: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
               GPT L+P T    + L A    P  A   +   P PTS
Sbjct: 1866 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1902



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%)

Query: 117  DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175
            D+  +  P +  G +I   G    ++      ++++ W   S LM++   K    Q  GL
Sbjct: 2119 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2175

Query: 176  CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228
            CG  DG   N+   ++G        + +   +DP        +PS  T V Q +      
Sbjct: 2176 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2227

Query: 229  -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281
                C+  L +V      A    V  E F      D     QP      C  L+ Y   C
Sbjct: 2228 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2281

Query: 282  SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332
                  +  WR    C    C ++  YQ C +AC   KTC        +P+H        
Sbjct: 2282 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2337

Query: 333  GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379
            GC C EGT+L+   ++  C+P  +C C    G   A GE   ++   C
Sbjct: 2338 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2384



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%)

Query: 794  TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847
            T   CVP   E  CV   C EG L      Q  P    P  C   G++   G +      
Sbjct: 1975 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2033

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
             C+C                C+++ +   +TFDG          YIL         SQ  
Sbjct: 2034 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2069

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967
             ++LT +V+       C  A    L      L   N T      H+   VT    +  V 
Sbjct: 2070 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2117

Query: 968  ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003
            + +        RY   +    HM                   +++  ++ S+    GLCG
Sbjct: 2118 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2177

Query: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057
              +G+  +D   +   V   A      ++SW+        G   F  D C         A
Sbjct: 2178 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2228

Query: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113
               CS    +++++TF+ CH  V    + E  +RD             C A+  Y   C 
Sbjct: 2229 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2282

Query: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137
               VC++WR   +CP  C   +T+
Sbjct: 2283 KFHVCIEWRRSDYCPFLCSSDSTY 2306



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 58/270 (21%), Positives = 106/270 (39%), Gaps = 22/270 (8%)

Query: 2088 ISSSSWLPQNS---SSRPPSSPITT---QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV 2141
            +  + W+P  +    + PPS  + T   + P LS  +    T        + +P+AP T 
Sbjct: 1392 VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP-----ALTPAAPLTT 1446

Query: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT--LSSGSHSSLSTHPTTASVSASPLFP 2199
            +   P + +     SP  G + + +  P+  T   L +G   S ++   TAS+ A P  P
Sbjct: 1447 ALNPPVTATEEPVVSP--GPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1504

Query: 2200 SSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259
             S +    ++   P  +S     + +    TV  + +P+  ++S +   P  P  T +  
Sbjct: 1505 ESSSLPVALQTPTPGMVSGAMETTRV----TVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1560

Query: 2260 TAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFL 2319
                 S    T+      T  P+S  V+    ++  PTS  ++     P  T   +   +
Sbjct: 1561 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1620

Query: 2320 TSSLTAHGSTPASAPVSSLGT---PTPTSP 2346
                 A  ++  S P++  GT     P SP
Sbjct: 1621 PQPTQAQSASSPSTPLTVAGTAAEQVPVSP 1650



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
            V +  C+G C SA+ +N         C CCR +    + ++L C   +T    +  T+Q 
Sbjct: 2787 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2843

Query: 2427 FSHCVC 2432
             + C C
Sbjct: 2844 PTDCAC 2849


>gi|239744298 PREDICTED: otogelin isoform 1 [Homo sapiens]
          Length = 2924

 Score =  512 bits (1318), Expect = e-144
 Identities = 350/1152 (30%), Positives = 520/1152 (45%), Gaps = 87/1152 (7%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGAS 104
            C  WG  H  TFD   Y  SG  +Y      +    +FS+Q+   P    S        S
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210

Query: 105  VVTVSEAIISV-KDI---GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSH 159
            +  V E  I + K++   G+ + LP+     ++    Q    V  + +    + W   S 
Sbjct: 211  LFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQ---QLAGYVIVRHQSAFTLAWDGASA 267

Query: 160  LMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-----HKFAALQKLDDPGEICT 214
            + + +  + +G   GLCGN +    ++ V+  GK  +      H +        PG   T
Sbjct: 268  VYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGP--T 325

Query: 215  FQDIPSTHVRQAQHARI------CTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGP 266
               +P     Q     +      C  LL      C   VS  PF  SC +D+  +   G 
Sbjct: 326  TSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSM--GD 383

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSP-GLCSVGQCPANQVYQECGSACVKTCSNPQHS 325
              + C  L+EY+R C+  G+P++ WR+    C+V        Y EC + C  +C +P+ S
Sbjct: 384  VATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASC-HPRAS 442

Query: 326  CSSS---CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
            C  S   C  GC+CP G +  D      CV   +CPC  HG +Y PG V    C TC CT
Sbjct: 443  CVDSEIACVDGCYCPNGLIFEDGG----CVAPAECPCEFHGTLYPPGSVVKEDCNTCTCT 498

Query: 383  LGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKS 442
             G+W C+   CP  CS+ G    TTFD R Y F  TC YIL +S      G        +
Sbjct: 499  SGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRS---SGTFTVTLQNA 555

Query: 443  --GVSHSETSLVAVVYLSRQD---KIVISQDEVVTNNGEAKWLP-YKTRNITVFRQTSTH 496
              G++     + +V  +  QD   ++ ++Q   V    + K +P Y      + R +S  
Sbjct: 556  PCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVF 615

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L++ T+ G+ ++   R   + Y+ V  ++   T GLCG FNG+T DDF + +G+ E T  
Sbjct: 616  LRVRTNVGVRVLYD-REGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQ 674

Query: 557  LFVDSWRAGNC--PAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPF 614
            LF +SW+  +   P       DPC +       +   CS+L  TG +F  C A ++P P+
Sbjct: 675  LFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVL--TGEMFAPCSAFLSPVPY 732

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
            +++C   AC   +  P +CA L  Y H C   G+ +  +R+ +  C + C  +  +S   
Sbjct: 733  FEQCRRDACRCGQ--PCLCATLAHYAHLCRRHGLPV-DFRARLPACALSCEASKEYSPCV 789

Query: 675  QACERTCLSLSDRAT------------ECHHSAVPVDGCNCPDGTYLNQKGE-CVRKAQC 721
              C RTC  L+                EC      V+GC CP  TYL+ + + CV + QC
Sbjct: 790  APCGRTCQDLASPEACGVDGGDDLSRDEC------VEGCACPPDTYLDTQADLCVPRNQC 843

Query: 722  PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781
             C  +G  +   +      G  CHC +G +SC  R     A+C A + F +CS    +  
Sbjct: 844  SCHFQGVDYPPGDSDIPSLG-HCHCKDGVMSCDSRAPA--AACPAGQVFVNCSDLHTD-L 899

Query: 782  GAACAPTC-QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGA 840
              +   TC Q L          C  GC C +GL  + D  C  PEECPC + G  Y  G 
Sbjct: 900  ELSRERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDA-CFLPEECPCTWKGKEYFPGD 958

Query: 841  ELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCG 900
            ++ + C TC C RG + C     C STCT YG+ H  TFDG  F F G C+  L      
Sbjct: 959  QVMSPCHTCVCQRGSFQCTLHP-CASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSD 1017

Query: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEE-PHVQLGVTP 959
            V+     F ++ ENV C +SG+ C + I I +G   +V  D +   + E     +  V  
Sbjct: 1018 VS-----FSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHT 1072

Query: 960  GALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRY 1019
              +     +  P  + +TL+W++  T+ ++     Q  L GLCGNF+    ++  T    
Sbjct: 1073 WRVGFFTLVHFPQEH-ITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENL 1131

Query: 1020 VASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHL 1079
              ++  E  +SW     C D     D C LN  R  +A+++CS++ S+ F  CH  V   
Sbjct: 1132 ELTNPQEFGSSWAAVE-CPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVT 1190

Query: 1080 PYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ 1139
             +Y  C+ D CGC  GGDCEC C +V+AYA  C   GV VDWRTP  CP  C F+N    
Sbjct: 1191 WFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVL- 1249

Query: 1140 DGHGEYQYTQEA 1151
             G G YQ +  A
Sbjct: 1250 -GKGPYQLSSLA 1260



 Score =  226 bits (577), Expect = 2e-58
 Identities = 218/864 (25%), Positives = 335/864 (38%), Gaps = 197/864 (22%)

Query: 397  CSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSHSETSLVAV 454
            C   G   V TFD   Y   G  +Y L+   +       + V++  + G S    S    
Sbjct: 151  CRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQSFSIQVHNDPQCGSSPYTCSRAVS 210

Query: 455  VYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPI 514
            ++   + +I ++++  VT+ G    LP+           S  LQ    +   ++V+ +  
Sbjct: 211  LFFVGEQEIHLAKE--VTHGGMRVQLPHV--------MGSARLQQLAGY---VIVRHQSA 257

Query: 515  FQ--------AYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN 566
            F          Y+ + P+  G T GLCGN N D  DD  TS G        FV SW+   
Sbjct: 258  FTLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQE-- 315

Query: 567  CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACN-Y 625
               A  +   P + S     C + +   +     V+E+C A + P        + AC+ Y
Sbjct: 316  --QAPNQPPGPTTSSLPRPPCLQQNPGTMQG---VYEQCEALLRPP-------FDACHAY 363

Query: 626  EETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLS 685
                P                              T  CT +             C S+ 
Sbjct: 364  VSPLPF-----------------------------TASCTSDL------------CQSMG 382

Query: 686  DRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCH 745
            D AT C   A     C                 AQ    L+G++       T +   T H
Sbjct: 383  DVATWCRALAEYARAC-----------------AQAGRPLQGWR-------TQLRQCTVH 418

Query: 746  CINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEP 805
            C         + + F        T+  C         A+C P    + + +ACV      
Sbjct: 419  C---------KEKAF--------TYNECIACCP----ASCHPRASCVDSEIACVD----- 452

Query: 806  GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
            GC C  GL    DG CV P ECPCEF G  YP G+ +  DC TC+C+ G+W C     CP
Sbjct: 453  GCYCPNGLIFE-DGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAV-CP 510

Query: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG-NSGVTC 924
            + C++ G+ H  TFDG+R+ F   C+YILA      + S  TF +  +N  CG N    C
Sbjct: 511  AECSVTGDIHFTTFDGRRYTFPATCQYILAK-----SRSSGTFTVTLQNAPCGLNQDGAC 565

Query: 925  SRAIKIFLGG---LSVVLADRNYTVTGEEPHVQLGVTPGALSL----VVDISIPGRYNLT 977
             +++ + L       V L      +  ++  +    T  A  +     V + +     + 
Sbjct: 566  VQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVR 625

Query: 978  LIWNRH-MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPL 1036
            ++++R  + + +++ +   +   GLCG FNGN +DDF +      S+     NSWK    
Sbjct: 626  VLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSA 685

Query: 1037 CGDV--SFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDS 1094
            C  +      DPC ++    S++ + CSV+  + FA C + +  +PY+E C RDAC C  
Sbjct: 686  CSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQ 745

Query: 1095 GGDCECLCDAVAAYAQACLDKGVCVDWRT--PAFCPIYCGFYNTHTQDGHGEYQYTQEAN 1152
                 CLC  +A YA  C   G+ VD+R   PA C + C                     
Sbjct: 746  ----PCLCATLAHYAHLCRRHGLPVDFRARLPA-CALSC--------------------E 780

Query: 1153 CTWHYQPCLCP--------SQPQS--VPGSN-------IEGCYNCSQDEYFDHEEGVCVP 1195
             +  Y PC+ P        + P++  V G +       +EGC  C  D Y D +  +CVP
Sbjct: 781  ASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCA-CPPDTYLDTQADLCVP 839

Query: 1196 -----CMPPTTPQPPTTPQLPTTG 1214
                 C       PP    +P+ G
Sbjct: 840  RNQCSCHFQGVDYPPGDSDIPSLG 863



 Score =  118 bits (295), Expect = 8e-26
 Identities = 114/402 (28%), Positives = 172/402 (42%), Gaps = 43/402 (10%)

Query: 38  TAPDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG----- 92
           TA    +CS  G  HF+TFD   Y F  TC YI A +      TF+V L+  P G     
Sbjct: 506 TAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSG--TFTVTLQNAPCGLNQDG 563

Query: 93  ----SISRIIVELGASVVTVSEA-IISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE 147
               S+S I+ +     VT+++A  + + D   I  PYT +  +I     S   +  +  
Sbjct: 564 ACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRL--SSVFLRVRTN 621

Query: 148 LELEVVWGPDS-HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFAALQK 205
           + + V++  +   L + V+++++    GLCG F+G   ++F+S  G     P  F    K
Sbjct: 622 VGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWK 681

Query: 206 ---LDDPGEICTFQDIPSTHVRQAQHA-RICTQLLTLVAPECS--VSKEPFVLSCQADVA 259
                 P    +  D    H++ A ++ + C+ L   +   CS  +S  P+   C+ D  
Sbjct: 682 TLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDAC 741

Query: 260 AAPQPGPQNSSCATLSEYSRQCSMVGQPVR-RWRSPGLCSVGQCPANQVYQECGSACVKT 318
              QP      CATL+ Y+  C   G PV  R R P  C++  C A++ Y  C + C +T
Sbjct: 742 RCGQP----CLCATLAHYAHLCRRHGLPVDFRARLPA-CAL-SCEASKEYSPCVAPCGRT 795

Query: 319 CSN--PQHSCS---------SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYA 367
           C +     +C            C  GC CP  T L+  ++   CVP  QC C   G  Y 
Sbjct: 796 CQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQAD--LCVPRNQCSCHFQGVDYP 853

Query: 368 PGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFD 409
           PG+  I +   C C  G   C  R  P      G  FV   D
Sbjct: 854 PGDSDIPSLGHCHCKDGVMSCDSR-APAAACPAGQVFVNCSD 894



 Score =  111 bits (277), Expect = 1e-23
 Identities = 117/426 (27%), Positives = 164/426 (38%), Gaps = 67/426 (15%)

Query: 802  KCEPGCV--CAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQ 859
            KC P  +  C  G      G+CV P  C C     + P               R +    
Sbjct: 104  KCAPSYLFSCFNG------GECVHPAFCDCRRFNATGP---------------RCQMVYN 142

Query: 860  QGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQ-PTFKILTEN-VIC 917
             G    S C  +G+ HV TFDG  +   G   Y L     G ++ +  +F I   N   C
Sbjct: 143  AGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLV----GRHEPEGQSFSIQVHNDPQC 198

Query: 918  GNSGVTCSRAIKIFLGGLSVVLADRNYTVTG---EEPHVQLGVTPGALSLVVDISIPGRY 974
            G+S  TCSRA+ +F  G   +   +  T  G   + PHV        L+  V +     +
Sbjct: 199  GSSPYTCSRAVSLFFVGEQEIHLAKEVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAF 258

Query: 975  NLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKES 1034
              TL W+    + I+++        GLCGN N + KDD  T S  +    +E V+SW+E 
Sbjct: 259  --TLAWDGASAVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQ 316

Query: 1035 -----PLCGDVSFVTDPC-SLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRD 1088
                 P     S    PC   N         +C  +    F  CH+ V  LP+  +C  D
Sbjct: 317  APNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSD 376

Query: 1089 ACGCDSGGDCECLCDAVAAYAQACLDKGVCVD-WRTP-AFCPIYCGFYNTHTQDGHGEYQ 1146
               C S GD    C A+A YA+AC   G  +  WRT    C ++C             + 
Sbjct: 377  L--CQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHC---------KEKAFT 425

Query: 1147 YTQEANCTWHYQPCLCPSQPQSVPG--SNIEGCYNCSQDEYFDHEEGVCV-----PCMPP 1199
            Y +   C     P  C  +   V    + ++GCY C     F  E+G CV     PC   
Sbjct: 426  YNECIACC----PASCHPRASCVDSEIACVDGCY-CPNGLIF--EDGGCVAPAECPCEFH 478

Query: 1200 TTPQPP 1205
             T  PP
Sbjct: 479  GTLYPP 484



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 146/606 (24%), Positives = 231/606 (38%), Gaps = 63/606 (10%)

Query: 1510 SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN-SATSSR 1568
            SQ   + S  +   S  S  + TH P +TP +  T   NP  T T  PV     + T+ +
Sbjct: 1483 SQGLPTPSDEEPQLSQESPRTPTHRPALTPAAPLTTALNPPVTATEEPVVSPGPTQTTLQ 1542

Query: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 1628
             P   T    P G +   ++  +TA+      T P  S     L T  P   +  +  + 
Sbjct: 1543 QPLELTASQLPAGPTESPASKGVTASLLAIPHT-PESSSLPVALQTPTPGMVSGAMETTR 1601

Query: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPT---TLKATGS---THTAPTMTLTTSGTSQAL 1682
             TVI      +  S+   S P    P  T   T++  GS     T P  +LT S +S+ +
Sbjct: 1602 VTVIFAGSPNITVSS--RSPPAPRFPLMTKAVTVRGHGSLPVRTTPPQPSLTASPSSRPV 1659

Query: 1683 SSLNT-AKTSTSLHSHTSSTHHAEATSTSTTNITPNPT---STGTPPMTVTTSGTSQSR- 1737
            +S    +++ TS  SH +    A     S T + P PT   S  +P   +T +GT+  + 
Sbjct: 1660 ASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV-PQPTQAQSASSPSTPLTVAGTAAEQV 1718

Query: 1738 --SSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
              S  +T      L +      H +    S  S  P+   +    P  HTT AT S    
Sbjct: 1719 PVSPLATRSLEIVLSTEKGEAGHSQPMG-SPASPQPHPLPSAPPRPAQHTTMATRSPALP 1777

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQT-TTTYPTP----SHPHTTLPTHVPSFSTSLVTP 1850
            P T    P   +  ++T  + AT F +  +T P+       P T+LP      S  + TP
Sbjct: 1778 PET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATP 1833

Query: 1851 STHTVIIPTHTQMATSASIHSMPTGTIPP--PTTIKATGSTHTAPPMTPTTSGTSQSPSS 1908
                 +I T  Q   +    ++P  T+ P  P T  A    H    + P  +GT+     
Sbjct: 1834 GPKASVITTPLQPQAT----TLPAQTLSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLL 1889

Query: 1909 FSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT 1968
             +T  TS  LP    +         S  ++ P+ ++TG    ++   S     LPT    
Sbjct: 1890 GATLPTSGVLPVAEGT--------ASMVSVVPRKSTTGKVAILSKQVS-----LPTSM-- 1934

Query: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ--TTLPTHVPPFSTSLVTPSTHTV-- 2024
                 GS+    T    ATS   T     P   Q  T LP    P S +L   S  T   
Sbjct: 1935 ----YGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPV---PTSYALSRVSARTAPQ 1987

Query: 2025 --IITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTAT 2082
              ++    Q+A +    + P     P        S  +AP +++   G ++  ++ + A 
Sbjct: 1988 DSMLVLLPQLAEAHGTSAGPHLAAEPVDEATTEPSGRSAPALSI-VEGLAEALATTTEAN 2046

Query: 2083 ASSSFI 2088
             S++ +
Sbjct: 2047 TSTTCV 2052



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 128/530 (24%), Positives = 195/530 (36%), Gaps = 74/530 (13%)

Query: 344  DLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC-------RCTL--------GRWVC 388
            + + + TCVP+ +  CV H  +     + +   Q C       RC +        G   C
Sbjct: 2044 EANTSTTCVPIAEQDCVRHICLEGQ-LIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCC 2102

Query: 389  TERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYD--KSGVSH 446
                C   CS+       TFD           YIL QSP   ++   + V D   + + H
Sbjct: 2103 PLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSP---DEMLTVHVLDCKSANLGH 2159

Query: 447  SETSLVAVVYLSRQD---KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATS 502
                   +V L+      ++ I + +  VT + +  W P       +  + + H+ M  +
Sbjct: 2160 LNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRI--EDTGHMYMILT 2217

Query: 503  FGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTA---SLFV 559
                 +  L       V      + Q  GLCG  +GD  +D T   G   G A   + F+
Sbjct: 2218 PSDIQIQWLHSSGLMIVEASKTSKAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFL 2277

Query: 560  DSWRAGNCPAALERETDPCSMSQLNKV------CAETHCSMLLR--TGTVFERCHATVNP 611
            DSW+             P S++ + +       CA T CS  LR  +   F  CH  V P
Sbjct: 2278 DSWQV------------PSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPP 2325

Query: 612  APFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFS 671
              F +  +      ++     C AL  YV  C    V +  WR S D C   C+ ++T+ 
Sbjct: 2326 ESFCELWIRDTKYVQQP----CVALTVYVAMCHKFHVCI-EWRRS-DYCPFLCSSDSTYQ 2379

Query: 672  YNSQACE--RTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGE--CVRKAQCPCI-LE 726
                ACE  +TC        +  H  V  +GC C +GT L+++    C+ +A+C C    
Sbjct: 2380 ACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSM 2439

Query: 727  GYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACA 786
            G    L E     N     C   +   P         C +P+  +SC +  E    A   
Sbjct: 2440 GVPRALGE---TWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRP-ESCLRFGE---VALLL 2492

Query: 787  PTCQMLATGVACV--PTKCE---PGCVCAEGLYEN-ADGQCVPPEECPCE 830
            PT      G  CV   T CE   P C     L  +  +  C P   C C+
Sbjct: 2493 PTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECD 2542



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 174/731 (23%), Positives = 248/731 (33%), Gaps = 102/731 (13%)

Query: 1153 CTWHYQPCLCPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP-CMPPTTPQPPTTPQLP 1211
            C W Y  C  P   Q+        C +  +          CVP C  P      T   + 
Sbjct: 1408 CEWRYDACASPCF-QTCRDPRAASCRDVPRGRS-------CVPVCPTPQVLDEVTQRCVY 1459

Query: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTG-PSPS------SNHTPASPTQTPLLPATLTSSKP 1264
                    VW  T       L  S G P+PS      S  +P +PT  P     LT + P
Sbjct: 1460 LEDCVEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP----ALTPAAP 1515

Query: 1265 TASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQST 1324
              ++  PP  T    P  + G  PT T      + T +Q     T S AS   T++  + 
Sbjct: 1516 LTTALNPP-VTATEEPVVSPG--PTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAI 1572

Query: 1325 TRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPT 1384
              T  +   P    T      S   E    T      P  T +S    + P P  P    
Sbjct: 1573 PHTPESSSLPVALQTPTPGMVSGAMETTRVTVIFAGSPNITVSSR---SPPAPRFPLMTK 1629

Query: 1385 ATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLP 1444
            A       +    TTP  P  T SP  +  PV S G ++ +        PT S       
Sbjct: 1630 AVTVRGHGSLPVRTTPPQPSLTASP--SSRPVASPGAISRS--------PTSSGSH---- 1675

Query: 1445 THVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504
                    +++TP+   VI+ T     T A + S+P+      T L   G+     P++P
Sbjct: 1676 -------KAVLTPAVTKVISRTGVPQPTQAQSASSPS------TPLTVAGTAAEQVPVSP 1722

Query: 1505 TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSA 1564
                T       ST K     HS       P  +P S     P+P  +    P  HT  A
Sbjct: 1723 L--ATRSLEIVLSTEKGEAG-HS------QPMGSPASP---QPHPLPSAPPRPAQHTTMA 1770

Query: 1565 TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-TTTYPTP----SHPQTTLPTHVPPF 1619
            T S   PP T    P  +S  ++T  + AT F +  +T P+       P T+LP      
Sbjct: 1771 TRSPALPPET----PAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGT 1826

Query: 1620 STSLVT--PSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSG 1677
            S  + T  P    + TP   Q  T  +    P     P    +A   TH AP      +G
Sbjct: 1827 SAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAP----PAAG 1882

Query: 1678 TSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSR 1737
            T+  L    T  TS  L         AE T+ S  ++ P  ++TG   + + +   S   
Sbjct: 1883 TAPGLLLGATLPTSGVLPV-------AEGTA-SMVSVVPRKSTTG--KVAILSKQVSLPT 1932

Query: 1738 SSFSTAK------TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSS 1791
            S + +A+      T  + H  T     PE     T    P  TS       A T    S 
Sbjct: 1933 SMYGSAEGGPTELTPATSHPLTPLVAEPEGAQAGTALPVP--TSYALSRVSARTAPQDSM 1990

Query: 1792 RLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPS 1851
             +  P    +  T   P  +  PV     + TT     S P  ++   +     +    +
Sbjct: 1991 LVLLPQLAEAHGTSAGPHLAAEPVD----EATTEPSGRSAPALSIVEGLAEALATTTEAN 2046

Query: 1852 THTVIIPTHTQ 1862
            T T  +P   Q
Sbjct: 2047 TSTTCVPIAEQ 2057



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 68/270 (25%), Positives = 113/270 (41%), Gaps = 23/270 (8%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCN-YIFAATCKDAFPTFSVQLRRGPDGSISRII 98
            P    C+ +G  H+ TFD   +DF G C  ++  +T   +F      +     G I R  
Sbjct: 980  PCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKF 1039

Query: 99   VELGASVVTVSEAIISVKDIGVISLP--YTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +      + V  ++I   D      P  +  +  ++  +      +    +  + ++W  
Sbjct: 1040 IS-----INVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQ 1094

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKF----AALQKLD--DP 209
             + + V    ++ GQ+ GLCGNFD K  NE  + E  +   P +F    AA++  D  DP
Sbjct: 1095 RTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDP 1154

Query: 210  GEICTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQ 267
             ++C    +     R+    + C+ LL+ V   C   V    F  +C  D     Q G  
Sbjct: 1155 RDMCVLNPL-----REPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDC 1209

Query: 268  NSSCATLSEYSRQCSMVGQPVRRWRSPGLC 297
               CA++S Y+ QC   G  V  WR+P LC
Sbjct: 1210 ECFCASVSAYAHQCCQHGVAV-DWRTPRLC 1238



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 124/521 (23%), Positives = 202/521 (38%), Gaps = 76/521 (14%)

Query: 1876 TIPP----PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931
            T+PP    PT            P TPT       P+    A  +T+L    ++T  P V+
Sbjct: 1479 TLPPSQGLPTPSDEEPQLSQESPRTPT-----HRPALTPAAPLTTALNPPVTATEEPVVS 1533

Query: 1932 PTST-TNITPKHTSTGTRTPVAHTTSASSSRLPTPFTT--HSPPTGSSPFSSTGP---MT 1985
            P  T T +      T ++ P   T S +S  +        H+P + S P +   P   M 
Sbjct: 1534 PGPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTPESSSLPVALQTPTPGMV 1593

Query: 1986 ATSFQTT-TTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
            + + +TT  T      P  T+ +  PP                  T+  T     S P  
Sbjct: 1594 SGAMETTRVTVIFAGSPNITVSSRSPPAPR-----------FPLMTKAVTVRGHGSLPVR 1642

Query: 2045 TVPPPTTLKATGSTH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNS---SS 2100
            T PP  +L A+ S+   A P  ++ S TS + S  +  T + + + S + +PQ +   S+
Sbjct: 1643 TTPPQPSLTASPSSRPVASPGAISRSPTS-SGSHKAVLTPAVTKVISRTGVPQPTQAQSA 1701

Query: 2101 RPPSSPITT------QLP-----------HLSSATTPVSTTNQLSSSFSPSPSAPSTVSS 2143
              PS+P+T       Q+P            LS+       +  + S  SP P  P   + 
Sbjct: 1702 SSPSTPLTVAGTAAEQVPVSPLATRSLEIVLSTEKGEAGHSQPMGSPASPQPH-PLPSAP 1760

Query: 2144 YVPSSHSSPQTSSP----------SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
              P+ H++  T SP          S+ T++  ++A    +  S+     LS  P   S+ 
Sbjct: 1761 PRPAQHTTMATRSPALPPETPAAASLSTATDGLAATPFMSLESTRPSQLLSGLPPDTSLP 1820

Query: 2194 ASPLFPSSPAASTTIRATLPHTISSP-------FTLSALLPISTVTVSPT-PSSHLASST 2245
             + +  S+P A+   +A++  T   P        TLS +LP +   ++   P +H+A   
Sbjct: 1821 LAKVGTSAPVATPGPKASVITTPLQPQATTLPAQTLSPVLPFTPAAMTQAHPPTHIAPPA 1880

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
                      A+  T+        T+   S+  R  T+G V++ S    +PTS      +
Sbjct: 1881 AGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKSTTGKVAILSKQVSLPTS---MYGS 1937

Query: 2306 RHPGPT-LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
               GPT L+P T    + L A    P  A   +   P PTS
Sbjct: 1938 AEGGPTELTPATSHPLTPLVAE---PEGAQAGT-ALPVPTS 1974



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 70/288 (24%), Positives = 107/288 (37%), Gaps = 47/288 (16%)

Query: 117  DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGPDSHLMVLVERKYM-GQMCGL 175
            D+  +  P +  G +I   G    ++      ++++ W   S LM++   K    Q  GL
Sbjct: 2191 DLQPVWPPVSRYGFRIEDTGHMYMILTPS---DIQIQWLHSSGLMIVEASKTSKAQGHGL 2247

Query: 176  CGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEICTFQDIPS--THVRQAQH----- 228
            CG  DG   N+   ++G        + +   +DP        +PS  T V Q +      
Sbjct: 2248 CGICDGDAANDLTLKDG--------SVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC 2299

Query: 229  -ARICTQLLTLV------APECSVSKEPFVLSCQADVAAAPQPGPQNSSCATLSEYSRQC 281
                C+  L +V      A    V  E F      D     QP      C  L+ Y   C
Sbjct: 2300 ATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMC 2353

Query: 282  SMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC--VKTCS-------NPQHSCSSSCTF 332
                  +  WR    C    C ++  YQ C +AC   KTC        +P+H        
Sbjct: 2354 HKFHVCI-EWRRSDYCPF-LCSSDSTYQACVTACEPPKTCQDGILGPLDPEH--CQVLGE 2409

Query: 333  GCFCPEGTVLNDLSNNHTCVPVTQCPCV-LHGAMYAPGEVTIAACQTC 379
            GC C EGT+L+   ++  C+P  +C C    G   A GE   ++   C
Sbjct: 2410 GCVCSEGTILH-RRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGC 2456



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 84/384 (21%), Positives = 129/384 (33%), Gaps = 92/384 (23%)

Query: 794  TGVACVPTKCEPGCV---CAEG-LYENADGQCVPPEECP--CEFSGVSYPGGAELHTDCR 847
            T   CVP   E  CV   C EG L      Q  P    P  C   G++   G +      
Sbjct: 2047 TSTTCVPI-AEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLW 2105

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
             C+C                C+++ +   +TFDG          YIL         SQ  
Sbjct: 2106 ECACR---------------CSIFPDLSFVTFDGSHVALFKEAIYIL---------SQSP 2141

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD 967
             ++LT +V+       C  A    L      L   N T      H+   VT    +  V 
Sbjct: 2142 DEMLTVHVL------DCKSANLGHLNWPPFCLVMLNMT------HLAHQVTIDRFNRKVT 2189

Query: 968  ISIP------GRYNLTLIWNRHM------------------TILIRIARASQDPLCGLCG 1003
            + +        RY   +    HM                   +++  ++ S+    GLCG
Sbjct: 2190 VDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTSKAQGHGLCG 2249

Query: 1004 NFNGNMKDDFETRSRYV---ASSELELVNSWK---ESPLCGDVSFVTDPCSLNAFRRSWA 1057
              +G+  +D   +   V   A      ++SW+        G   F  D C         A
Sbjct: 2250 ICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSC---------A 2300

Query: 1058 ERKCS----VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACL 1113
               CS    +++++TF+ CH  V    + E  +RD             C A+  Y   C 
Sbjct: 2301 TTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQP------CVALTVYVAMCH 2354

Query: 1114 DKGVCVDWRTPAFCPIYCGFYNTH 1137
               VC++WR   +CP  C   +T+
Sbjct: 2355 KFHVCIEWRRSDYCPFLCSSDSTY 2378



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 58/270 (21%), Positives = 106/270 (39%), Gaps = 22/270 (8%)

Query: 2088 ISSSSWLPQNS---SSRPPSSPITT---QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTV 2141
            +  + W+P  +    + PPS  + T   + P LS  +    T        + +P+AP T 
Sbjct: 1464 VEPAVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRP-----ALTPAAPLTT 1518

Query: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT--LSSGSHSSLSTHPTTASVSASPLFP 2199
            +   P + +     SP  G + + +  P+  T   L +G   S ++   TAS+ A P  P
Sbjct: 1519 ALNPPVTATEEPVVSP--GPTQTTLQQPLELTASQLPAGPTESPASKGVTASLLAIPHTP 1576

Query: 2200 SSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259
             S +    ++   P  +S     + +    TV  + +P+  ++S +   P  P  T +  
Sbjct: 1577 ESSSLPVALQTPTPGMVSGAMETTRV----TVIFAGSPNITVSSRSPPAPRFPLMTKAVT 1632

Query: 2260 TAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFL 2319
                 S    T+      T  P+S  V+    ++  PTS  ++     P  T   +   +
Sbjct: 1633 VRGHGSLPVRTTPPQPSLTASPSSRPVASPGAISRSPTSSGSHKAVLTPAVTKVISRTGV 1692

Query: 2320 TSSLTAHGSTPASAPVSSLGT---PTPTSP 2346
                 A  ++  S P++  GT     P SP
Sbjct: 1693 PQPTQAQSASSPSTPLTVAGTAAEQVPVSP 1722



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%)

Query: 2367 VTVTRCEGACISAASFNIITQQVDARCSCCRPLHSYEQQLELPCPDPSTPGRRLVLTLQV 2426
            V +  C+G C SA+ +N         C CCR +    + ++L C   +T    +  T+Q 
Sbjct: 2859 VNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFC---ATNATWVPYTVQE 2915

Query: 2427 FSHCVC 2432
             + C C
Sbjct: 2916 PTDCAC 2921


>gi|134031945 SCO-spondin [Homo sapiens]
          Length = 5147

 Score =  483 bits (1243), Expect = e-135
 Identities = 345/1190 (28%), Positives = 499/1190 (41%), Gaps = 127/1190 (10%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGP----DGSISRIIVE 100
            C++W   H+ TFD   Y F G C Y+ A     A  T++V L  G      G   R  V 
Sbjct: 195  CASWSGFHYRTFDGRHYHFLGRCTYLLAGA---ADSTWAVHLTPGDRCPQPGHCQR--VT 249

Query: 101  LGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLE-----------LE 149
            +G   V +    +SVK              Q+ P GQS  L    L+           L 
Sbjct: 250  MGPEEVLIQAGNVSVKG-------------QLVPEGQSWLLHGLSLQWLGDWLVLSGGLG 296

Query: 150  LEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKF------------LEP 197
            + V       + + V+ +  GQ  GLCG ++G   ++F+   G              L  
Sbjct: 297  VVVRLDRTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPG 356

Query: 198  HKFAALQKLD-----DPGEICTFQDIPSTHVRQAQHARICTQLLTLVAPECSVSKEP--- 249
             +   L  ++     DP  +    D+   H+R A+   +C QLL     +C     P   
Sbjct: 357  SESGCLDAVEVAQGCDPLGLID-ADVEPGHLR-AEAQDVCHQLLEGPFGQCHAQVSPAEY 414

Query: 250  ----FVLSCQADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPAN 305
                    C   +A + Q G Q + CAT + Y + C+     +R WR PG C    CP  
Sbjct: 415  HEACLFAYCAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIR-WRKPGFCE-RLCPGG 472

Query: 306  QVYQECGSACVKTCS----NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVL 361
            Q+Y +C S C  +C       + SC   C  GC CP G   N       CVP   CPC  
Sbjct: 473  QLYSDCVSLCPPSCEAVGQGEEESCREECVSGCECPRGLFWNGT----LCVPAAHCPCYY 528

Query: 362  HGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGT--C 419
                Y PG+     C  C C  GRW C +  CP  C++ G     TFD R Y F G   C
Sbjct: 529  CRQRYVPGDTVRQLCNPCVCRDGRWHCAQALCPAECAVGGDGHYLTFDGRSYSFWGGQGC 588

Query: 420  TYILLQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKW 479
             Y L+Q       G L+ + +  G   + + L A+        I +     V  NG+   
Sbjct: 589  RYSLVQDYV---KGQLLILLEH-GACDAGSCLHAISVSLEDTHIQLRDSGAVLVNGQDVG 644

Query: 480  LPY-KTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNG 538
            LP+     ++V R +S  L +       L     P+  AY+T+ P+   Q +GLCG F  
Sbjct: 645  LPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSDPV--AYITLDPRHAHQVQGLCGTFTQ 702

Query: 539  DTTDDFTTSMGIAEGTASLFVDSWRA---GNCPAALERETDPCSMSQLNKVCAETHCSML 595
            +  DDF T  G  E + + F   ++    G CP+       PC+        AE  C++L
Sbjct: 703  NQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSEDSALLSPCTTHSQRHAFAEAACAIL 762

Query: 596  LRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRS 655
                +VF+ CH  V+  PFY RC+   C  +     +C  L  Y   C+  G     WR+
Sbjct: 763  --HSSVFQECHRLVDKEPFYLRCLAAVCGCDPGSDCLCPVLSAYARRCAQEGASP-PWRN 819

Query: 656  SVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGEC 715
                C + C G   +   + AC + C     +  +C      V GCNCP G   + +G+C
Sbjct: 820  QT-LCPVMCPGGQEYRECAPACGQHC----GKPEDCGELGSCVAGCNCPLGLLWDPEGQC 874

Query: 716  VRKAQCPCILEGYKFILAEQSTVINGITCHCIN-GRLSCPQRPQMFLASCQAPKTFKSCS 774
            V  + CPC L G +      +T+     C C   G  +C  R     A C     +    
Sbjct: 875  VPPSLCPCQL-GARRYAPGSATMKECNRCICQERGLWNCTARHCPSQAFCPRELVYAP-- 931

Query: 775  QSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGV 834
                     AC  TC   +   +C P     GCVC  G     D +CVPP+ CPC  SG 
Sbjct: 932  --------GACLLTCDSPSANHSC-PAGSTDGCVCPPGTVL-LDERCVPPDLCPCRHSGQ 981

Query: 835  SYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYIL 894
             Y   A +  DC  C C   +W C  G      C   G  H +TFDG  F + G CEY+L
Sbjct: 982  WYLPNATIQEDCNVCVCRGRQWHCT-GQRRSGRCQASGAPHYVTFDGLAFTYPGACEYLL 1040

Query: 895  ATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSV-VLADRNYTVTGEE--- 950
              +  G+      F +  +N+ CG SG+TC++A+ + L G  V +L  R  TV G     
Sbjct: 1041 VREASGL------FTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTP 1094

Query: 951  PHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMK 1010
            P V  G         + + +     LTL+W+    +L++++   +  + GLCG+F+G+  
Sbjct: 1095 PKVYTGPGLSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQLSPQFRGRVAGLCGDFDGDAS 1154

Query: 1011 DDFETRSRYVASSELELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFA 1070
            +D  +R   +  +     +SW+ SPLC +   +  PC++N  R  WA  +C  +    F 
Sbjct: 1155 NDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLPHPCTMNTHRAGWARARCGALLQPLFT 1214

Query: 1071 TCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIY 1130
             CH++V    +YE C+ DACGCDSGGDCECLC A+A YA  C   G  V WR+   C + 
Sbjct: 1215 LCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECARHGHHVRWRSQELCSLQ 1274

Query: 1131 CGFYNTHTQDGH--GEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCY 1178
            C     +   G       + Q     WH Q   C           +EGC+
Sbjct: 1275 CEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVAC-----------VEGCF 1313



 Score =  201 bits (510), Expect = 1e-50
 Identities = 167/583 (28%), Positives = 231/583 (39%), Gaps = 98/583 (16%)

Query: 302  CPANQVYQECGSACVKTCSNPQ--HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPC 359
            CP   VY     AC+ TC +P   HSC +  T GC CP GTVL D      CVP   CPC
Sbjct: 923  CPRELVYAP--GACLLTCDSPSANHSCPAGSTDGCVCPPGTVLLD----ERCVPPDLCPC 976

Query: 360  VLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTC 419
               G  Y P       C  C C   +W CT +   G C   G     TFD   + + G C
Sbjct: 977  RHSGQWYLPNATIQEDCNVCVCRGRQWHCTGQRRSGRCQASGAPHYVTFDGLAFTYPGAC 1036

Query: 420  TYILLQSPQ-LPEDGALMAVYDKSGVSHSETSLV----AVVYLSRQDKIVIS-----QDE 469
             Y+L++    L    A       SG++ ++   V     VV++ R   + ++       +
Sbjct: 1037 EYLLVREASGLFTVSAQNLPCGASGLTCTKALAVRLEGTVVHMLRGRAVTVNGVSVTPPK 1096

Query: 470  VVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSF--GLELVVQLRPIFQAYVTVGPQFRG 527
            V T  G         R   +F   STHL +   +  G  ++VQL           PQFRG
Sbjct: 1097 VYTGPG------LSLRRAGLFLLLSTHLGLTLLWDGGTRVLVQL----------SPQFRG 1140

Query: 528  QTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGN-CPAALERETDPCSMSQLNKV 586
            +  GLCG+F+GD ++D  +  G+ E TA L   SWR    CP   +    PC+M+     
Sbjct: 1141 RVAGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLSPLCPEPGDLP-HPCTMNTHRAG 1199

Query: 587  CAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEE--TFPHICAALGDYVHACS 644
             A   C  LL+   +F  CHA V P   Y+ C+Y AC  +       +C+A+  Y   C+
Sbjct: 1200 WARARCGALLQP--LFTLCHAEVPPQQHYEWCLYDACGCDSGGDCECLCSAIATYADECA 1257

Query: 645  LRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCP 704
              G  +  WRS  + C++ C G   +      C  TC                V+GC CP
Sbjct: 1258 RHGHHV-RWRSQ-ELCSLQCEGGQVYEACGPTCPPTCHEQHPEPGWHCQVVACVEGCFCP 1315

Query: 705  DGTYLNQKGECVRKAQCPCILEGYKF----ILAEQSTVINGITCH--------------- 745
            +GT L+  G C+  A CPC      F    +L +        TC                
Sbjct: 1316 EGTLLHG-GACLEPASCPCEWGRNSFPPGSVLQKDC---GNCTCQEGQWHCGGDGGHCEE 1371

Query: 746  ----CINGRLSCPQR----PQMFLASCQAPKTFKSCSQSSENKFGAACAPTC---QMLAT 794
                C  G   C +     P  +L   Q       C   S+ +     AP C   QM  +
Sbjct: 1372 LVPACAEGEALCQENGHCVPHGWLCDNQ-----DDCGDGSDEE--GCAAPGCGEGQMTCS 1424

Query: 795  GVACVPTKC-------------EPGCVCAEGLYENADGQCVPP 824
               C+P                EP   C +GL   ADG+C+PP
Sbjct: 1425 SGHCLPLALLCDRQDDCGDGTDEPSYPCPQGLLACADGRCLPP 1467



 Score =  149 bits (375), Expect = 4e-35
 Identities = 112/375 (29%), Positives = 163/375 (43%), Gaps = 37/375 (9%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDG--SISRIIVE 100
            G+C   GA H+ TFD   + + G C Y+        F   +  L  G  G      + V 
Sbjct: 1012 GRCQASGAPHYVTFDGLAFTYPGACEYLLVREASGLFTVSAQNLPCGASGLTCTKALAVR 1071

Query: 101  LGASVVTVSEA-IISVKDIGVISLP-YTSNGLQITPFGQSVRLVAKQLELELEVVWGPDS 158
            L  +VV +     ++V  + V     YT  GL +   G  + L      L L ++W   +
Sbjct: 1072 LEGTVVHMLRGRAVTVNGVSVTPPKVYTGPGLSLRRAGLFLLL---STHLGLTLLWDGGT 1128

Query: 159  HLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP------HKFAALQKLDDPGEI 212
             ++V +  ++ G++ GLCG+FDG  +N+  S +G  LEP      H +       +PG++
Sbjct: 1129 RVLVQLSPQFRGRVAGLCGDFDGDASNDLRSRQG-VLEPTAELAAHSWRLSPLCPEPGDL 1187

Query: 213  ---CTFQDIPSTHVRQAQHARICTQLLTLVAPEC--SVSKEPFVLSCQADVAAAPQPGPQ 267
               CT     +TH      AR C  LL  +   C   V  +     C  D       G  
Sbjct: 1188 PHPCTM----NTHRAGWARAR-CGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSGGDC 1242

Query: 268  NSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTC--SNPQ-- 323
               C+ ++ Y+ +C+  G  V RWRS  LCS+ QC   QVY+ CG  C  TC   +P+  
Sbjct: 1243 ECLCSAIATYADECARHGHHV-RWRSQELCSL-QCEGGQVYEACGPTCPPTCHEQHPEPG 1300

Query: 324  -HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCT 382
             H    +C  GCFCPEGT+L    +   C+    CPC      + PG V    C  C C 
Sbjct: 1301 WHCQVVACVEGCFCPEGTLL----HGGACLEPASCPCEWGRNSFPPGSVLQKDCGNCTCQ 1356

Query: 383  LGRWVCTERPCPGHC 397
             G+W C      GHC
Sbjct: 1357 EGQWHCGGD--GGHC 1369



 Score =  137 bits (346), Expect = 1e-31
 Identities = 116/368 (31%), Positives = 157/368 (42%), Gaps = 29/368 (7%)

Query: 44  QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSISRIIVELGA 103
           +C+  G GH+ TFD   Y F G     ++           + L  G   + S     L A
Sbjct: 563 ECAVGGDGHYLTFDGRSYSFWGGQGCRYSLVQDYVKGQLLILLEHGACDAGSC----LHA 618

Query: 104 SVVTVSEAIISVKDIGVISLPYTSNGLQ-ITPFGQSVRLVAKQLEL----ELEVVWG-PD 157
             V++ +  I ++D G + +     GL  I   G SVR  +    L      +V+WG  D
Sbjct: 619 ISVSLEDTHIQLRDSGAVLVNGQDVGLPWIGAEGLSVRRASSAFLLLRWPGAQVLWGLSD 678

Query: 158 SHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKF-----LEPHKFAALQKLDDPGEI 212
               + ++ ++  Q+ GLCG F     ++F++  G           KF    K   P E 
Sbjct: 679 PVAYITLDPRHAHQVQGLCGTFTQNQQDDFLTPAGDVETSIAAFASKFQVAGKGRCPSED 738

Query: 213 CTFQDIPSTH-VRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQNS 269
                  +TH  R A     C  L + V  EC   V KEPF L C A V     PG  + 
Sbjct: 739 SALLSPCTTHSQRHAFAEAACAILHSSVFQECHRLVDKEPFYLRCLAAVCGC-DPG-SDC 796

Query: 270 SCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSCS-- 327
            C  LS Y+R+C+  G     WR+  LC V  CP  Q Y+EC  AC + C  P+  C   
Sbjct: 797 LCPVLSAYARRCAQEGAS-PPWRNQTLCPV-MCPGGQEYRECAPACGQHCGKPE-DCGEL 853

Query: 328 SSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRC-TLGRW 386
            SC  GC CP G + +       CVP + CPC L    YAPG  T+  C  C C   G W
Sbjct: 854 GSCVAGCNCPLGLLWDP---EGQCVPPSLCPCQLGARRYAPGSATMKECNRCICQERGLW 910

Query: 387 VCTERPCP 394
            CT R CP
Sbjct: 911 NCTARHCP 918



 Score =  110 bits (274), Expect = 2e-23
 Identities = 132/540 (24%), Positives = 203/540 (37%), Gaps = 79/540 (14%)

Query: 271 CATLSEYSRQCSMVGQP------VRRWRSPGLCSVGQCPA------NQVYQEC-----GS 313
           CA+L  YSR    +  P      + R  +PGLC + + P       N+  + C     G+
Sbjct: 42  CASLDHYSRLGWRLDLPWSGRSGLTRSPAPGLCPIYKPPETRPAKWNRTVRTCCPGWGGA 101

Query: 314 ACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCV--PVTQC-------PCVLHGA 364
            C +  +           + C    G+      +   C   P  Q         C    +
Sbjct: 102 HCTEALAKASPEGHCFAMWQCQLQAGSANASAGSLEECCARPWGQSWWDGSSQACRSCSS 161

Query: 365 MYAPGEVTIAAC-QTCRCTLGR-WVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYI 422
            + PG  +  A  Q     +G+ W   +RP    C+   G    TFD R Y F G CTY+
Sbjct: 162 RHLPGSASSPALLQPLAGAVGQLWSQHQRPS-ATCASWSGFHYRTFDGRHYHFLGRCTYL 220

Query: 423 LLQSPQ-------LPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNG 475
           L  +          P D      + +      E  L+    +S + ++V      + +  
Sbjct: 221 LAGAADSTWAVHLTPGDRCPQPGHCQRVTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGL 280

Query: 476 EAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535
             +WL                  +  S GL +VV+L       ++V  +  GQT+GLCG 
Sbjct: 281 SLQWLGD---------------WLVLSGGLGVVVRLDRTGSISISVDHELWGQTQGLCGL 325

Query: 536 FNGDTTDDFTTSMGIAEGTASLFVDSWR----AGNCPAALE--RETDPCSMSQLN----- 584
           +NG   DDF    G     A+ F +SWR       C  A+E  +  DP  +   +     
Sbjct: 326 YNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCLDAVEVAQGCDPLGLIDADVEPGH 385

Query: 585 -KVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQAC-------NYEETFPHICAAL 636
            +  A+  C  LL     F +CHA V+PA +++ C++  C         E     +CA  
Sbjct: 386 LRAEAQDVCHQLLE--GPFGQCHAQVSPAEYHEACLFAYCAGAMAGSGQEGRQQAVCATF 443

Query: 637 GDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATE-CHHSA 695
             YV AC+ R + +  WR     C   C G   +S     C  +C ++     E C    
Sbjct: 444 ASYVQACARRHIHI-RWRKP-GFCERLCPGGQLYSDCVSLCPPSCEAVGQGEEESCREEC 501

Query: 696 VPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQ 755
             V GC CP G + N    CV  A CPC     +++  +    +    C C +GR  C Q
Sbjct: 502 --VSGCECPRGLFWNGT-LCVPAAHCPCYYCRQRYVPGDTVRQLCN-PCVCRDGRWHCAQ 557



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 101/371 (27%), Positives = 150/371 (40%), Gaps = 55/371 (14%)

Query: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKI-LTENVICGNSGVTC 924
            +TC  +   H  TFDG+ + F G C Y+LA    G  DS  T+ + LT    C   G  C
Sbjct: 193  ATCASWSGFHYRTFDGRHYHFLGRCTYLLA----GAADS--TWAVHLTPGDRCPQPG-HC 245

Query: 925  SRAIKIFLGGLSVVLADRNYTVTGE-EPHVQLGVTPG-ALSLVVD-ISIPGRYNLTLIWN 981
             R   + +G   V++   N +V G+  P  Q  +  G +L  + D + + G   + +  +
Sbjct: 246  QR---VTMGPEEVLIQAGNVSVKGQLVPEGQSWLLHGLSLQWLGDWLVLSGGLGVVVRLD 302

Query: 982  RHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK---ESPLCG 1038
            R  +I I +         GLCG +NG  +DDF      +A       NSW+       C 
Sbjct: 303  RTGSISISVDHELWGQTQGLCGLYNGWPEDDFMEPGGGLAMLAATFGNSWRLPGSESGCL 362

Query: 1039 DVSFVT---DPCSL------NAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDA 1089
            D   V    DP  L          R+ A+  C  +    F  CH++V    Y+EAC+   
Sbjct: 363  DAVEVAQGCDPLGLIDADVEPGHLRAEAQDVCHQLLEGPFGQCHAQVSPAEYHEACLFAY 422

Query: 1090 C-----GCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQ----- 1139
            C     G    G  + +C   A+Y QAC  + + + WR P FC   C     ++      
Sbjct: 423  CAGAMAGSGQEGRQQAVCATFASYVQACARRHIHIRWRKPGFCERLCPGGQLYSDCVSLC 482

Query: 1140 ------DGHGEYQYTQEANCTWHYQPCLCP-----SQPQSVPGSNIEGCYNCSQDEYF-- 1186
                   G GE +  +E  C      C CP     +    VP ++   CY C Q  Y   
Sbjct: 483  PPSCEAVGQGEEESCRE-ECV---SGCECPRGLFWNGTLCVPAAHCP-CYYCRQ-RYVPG 536

Query: 1187 DHEEGVCVPCM 1197
            D    +C PC+
Sbjct: 537  DTVRQLCNPCV 547



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 70/221 (31%), Positives = 87/221 (39%), Gaps = 30/221 (13%)

Query: 664  CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC 723
            C      S  + +C   C  L   A        P  GC CP G  L+  G CV    CPC
Sbjct: 4818 CPPGQVLSACATSCPCLCWHLQPGAICVQEPCQP--GCGCPGGQLLHN-GTCVPPTACPC 4874

Query: 724  ILE----GYKFILAEQS------TVI--NGITCHCINGRLSCPQRPQMFLASCQAPKTFK 771
                   G    L EQ+      TV+  N   C C  G  SC       L  CQ P   +
Sbjct: 4875 TQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCS------LVDCQVPPG-E 4927

Query: 772  SCSQSSENKFGAACAPTC-QMLATGVA--CVPTKCEPGCVCAEGLYENADGQCVPPEECP 828
            +  Q +  + G  C  TC +M AT     C   +   GCVC  G + +  G CVP + C 
Sbjct: 4928 TWQQVAPGELGL-CEQTCLEMNATKTQSNCSSARAS-GCVCQPGHFRSQAGPCVPEDHCE 4985

Query: 829  CEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHC-PSTC 868
            C   G  +  G+E    C +C C  GR  C Q  HC P TC
Sbjct: 4986 CWHLGRPHLPGSEWQEACESCLCLSGRPVCTQ--HCSPLTC 5024



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 45/141 (31%), Positives = 65/141 (46%), Gaps = 25/141 (17%)

Query: 266  PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVY---QEC---GSACVKTC 319
            P +++C      +R C+   QP             QCP N ++   ++C   G  C + C
Sbjct: 2862 PGDTTCPGPHSQTRDCNT--QPC----------TAQCPENMLFRSAEQCHQEGGPCPRLC 2909

Query: 320  --SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT-IAAC 376
                P   C+  C  GC CP G  L+    N +C+P +QCPC LHG +YA G +  + +C
Sbjct: 2910 LTQGPGIECTGFCAPGCTCPPGLFLH----NASCLPRSQCPCQLHGQLYASGAMARLDSC 2965

Query: 377  QTCRCTLGRWVCTERPCPGHC 397
              C C  G+  CT   CP  C
Sbjct: 2966 NNCTCVSGKMACTSERCPVAC 2986



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 63/227 (27%), Positives = 83/227 (36%), Gaps = 46/227 (20%)

Query: 663  PCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP--------VDGCNCPDGTYLNQKGE 714
            PCT NT  +  ++A  R    L    T CH    P         D C C  G      G+
Sbjct: 1190 PCTMNTHRAGWARA--RCGALLQPLFTLCHAEVPPQQHYEWCLYDACGCDSG------GD 1241

Query: 715  CVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLA-SCQAPKTFKSC 773
            C    +C C             + I      C         R Q   +  C+  + +++C
Sbjct: 1242 C----ECLC-------------SAIATYADECARHGHHVRWRSQELCSLQCEGGQVYEAC 1284

Query: 774  SQSSENKFGAACAPTC--QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEF 831
                    G  C PTC  Q    G  C    C  GC C EG   +  G C+ P  CPCE+
Sbjct: 1285 --------GPTCPPTCHEQHPEPGWHCQVVACVEGCFCPEGTLLHG-GACLEPASCPCEW 1335

Query: 832  SGVSYPGGAELHTDCRTCSCSRGRWAC-QQGTHCPSTCTLYGEGHVI 877
               S+P G+ L  DC  C+C  G+W C   G HC        EG  +
Sbjct: 1336 GRNSFPPGSVLQKDCGNCTCQEGQWHCGGDGGHCEELVPACAEGEAL 1382



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 65/250 (26%), Positives = 89/250 (35%), Gaps = 62/250 (24%)

Query: 667  NTTFSYN-SQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCIL 725
            +T F+ + +  C  +C  L DR         P  GC CP G  L Q G CV  + C C L
Sbjct: 4671 DTVFTLDCANQCPHSCADLWDRVQCLQGPCRP--GCRCPPGQ-LVQDGRCVPISSCRCGL 4727

Query: 726  EGYKF---ILAEQSTVINGITCHCINGRLSCPQR------PQMFLASCQAP--------- 767
                    +   Q+  ++   C C+N  L CP +      P    +SC AP         
Sbjct: 4728 PSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERH 4787

Query: 768  ----------------------KTFKSCSQSSENKFGAACAPTCQMLA----TGVACVPT 801
                                     + C +    +  +ACA +C  L      G  CV  
Sbjct: 4788 RTCEGGPGVAPCQAQDTEQRQECNLQPCPECPPGQVLSACATSCPCLCWHLQPGAICVQE 4847

Query: 802  KCEPGCVCAEGLYENADGQCVPPEECPC-------------EFSGVSYPGGAELHTDCRT 848
             C+PGC C  G   + +G CVPP  CPC             E      P G  L  +C  
Sbjct: 4848 PCQPGCGCPGGQLLH-NGTCVPPTACPCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTR 4906

Query: 849  CSCSRGRWAC 858
            C C  G ++C
Sbjct: 4907 CVCHGGAFSC 4916



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 66/266 (24%), Positives = 85/266 (31%), Gaps = 78/266 (29%)

Query: 604  RCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIP 663
            R  + + P+P    C   A   E   P +C                +WG  +    C+ P
Sbjct: 2798 RSRSRLCPSPGDSSCPGDATQEEPCSPPVCPVPS------------IWGLWAPWSTCSAP 2845

Query: 664  CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC 723
            C G        Q   R+C SL+   T C         CN    T           AQCP 
Sbjct: 2846 CDGGI------QTRGRSCSSLAPGDTTCPGPHSQTRDCNTQPCT-----------AQCP- 2887

Query: 724  ILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGA 783
              E   F  AEQ        CH                                  + G 
Sbjct: 2888 --ENMLFRSAEQ--------CH----------------------------------QEGG 2903

Query: 784  ACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELH 843
             C   C     G+ C    C PGC C  GL+ + +  C+P  +CPC+  G  Y  GA   
Sbjct: 2904 PCPRLCLTQGPGIECTGF-CAPGCTCPPGLFLH-NASCLPRSQCPCQLHGQLYASGAMAR 2961

Query: 844  TD-CRTCSCSRGRWACQQGTHCPSTC 868
             D C  C+C  G+ AC     CP  C
Sbjct: 2962 LDSCNNCTCVSGKMAC-TSERCPVAC 2986



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 40/113 (35%), Positives = 52/113 (46%), Gaps = 12/113 (10%)

Query: 293  SPGLCSVGQCPANQVYQECGSACVKTCSNPQHS--CSSS--CTFGCFCPEGTVLNDLSNN 348
            +P  C  G CPA      C + C + CS+ Q    C     C  GC CP+G+    L  +
Sbjct: 4054 NPMPCEAG-CPAGMEVVTCANRCPRRCSDLQEGIVCQDDQVCQKGCRCPKGS----LEQD 4108

Query: 349  HTCVPVTQCPCV-LHGAMYAPGEVTIAACQTCRCTLGRWVCTERPC--PGHCS 398
              CVP+  C C    G  +APG     AC  C C  G+  CT +PC  P HC+
Sbjct: 4109 GGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCSCQAGQLSCTAQPCPPPTHCA 4161



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 60/212 (28%), Positives = 78/212 (36%), Gaps = 53/212 (25%)

Query: 679  RTCLSLSDRATECHHSAVPVDG----------CNCPDGTYLNQKGECVRKAQCPCILEGY 728
            + C     ++  C  +A PVDG          C+ P       +G   R+ QC     G 
Sbjct: 1730 QNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPC------RGTMTRQRQCHSPQNG- 1782

Query: 729  KFILAEQSTVINGITCHCINGRLS-------CPQR--PQMFLASCQAPKTFKSCSQSSEN 779
                        G TC  + G L        CPQ   P    A+C     F+ C      
Sbjct: 1783 ------------GRTCAALPGGLHSTRQTKPCPQDGCPN---ATCSGELMFQPC------ 1821

Query: 780  KFGAACAPTCQMLATGVACVPT-KC-EPGCVCAEGLYENADGQCVPPEECPCEFSGVSYP 837
               A C  TC  ++  V C P   C  PGC C EG    ++G CV P +CPC   G  Y 
Sbjct: 1822 ---APCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQCPCLVDGARYW 1878

Query: 838  GGAELHTDCRTCSCSRGR-WACQQGTHCPSTC 868
             G  +  DC+ C C  GR   C+    C   C
Sbjct: 1879 PGQRIKADCQLCICQDGRPRRCRLNPDCAVDC 1910



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 33/97 (34%), Positives = 47/97 (48%), Gaps = 8/97 (8%)

Query: 300  GQCPANQVYQEC--GSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQC 357
            G CP ++ + +C  G A     S P+ + + +C  GC CP G +L     N+ CVP   C
Sbjct: 3088 GMCPRDKQWLDCAQGPASCAELSAPRGT-NQTCHPGCHCPSGMLLL----NNVCVPTQDC 3142

Query: 358  PCVLHGAMYAPGEVTIAACQTCRCTLGRWV-CTERPC 393
            PC   G +Y PG   +  C+ C C  G    C+  PC
Sbjct: 3143 PCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPC 3179



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 9/104 (8%)

Query: 297  CSVGQCPANQ--VYQECGSACVKTCSNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPV 354
            C V  C A +   Y  CG  C ++C +  H C   C  GC+CP G VL+  SN   CV  
Sbjct: 3306 CPVTNCTAIEGAEYSPCGPPCPRSCDDLVH-CVWRCQPGCYCPPGQVLS--SNGAICVQP 3362

Query: 355  TQCPCV--LHGAMYAPGEVTIA--ACQTCRCTLGRWVCTERPCP 394
              C C+  L G  + PG        C  C C  GR  CT+ PCP
Sbjct: 3363 GHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 54/178 (30%), Positives = 74/178 (41%), Gaps = 31/178 (17%)

Query: 246  SKEPFVLSCQADVAAAPQP--GPQNSSCATLSEYSRQCSMVGQPVRRWRSP--------- 294
            S+  FV +C    A A     GP + SC      SRQ S V  P +   +P         
Sbjct: 2544 SQSCFVQACPVAGAWAMWEAWGPCSVSCGG-GHQSRQRSCVDPPPKNGGAPCPGASQERA 2602

Query: 295  --GL--CSVG-QCPANQVYQECGSA-------CVKTCSNPQ--HSCSSSCTFGCFCPEGT 340
              GL  CS G  C   +VY             C  +C +P+   SCS  C  GC CP G 
Sbjct: 2603 PCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGL 2662

Query: 341  VLNDLSNNHTCVPVTQCPCVLHGAMYAPG-EVTIAACQTCRCTLGRWVCTERPCPGHC 397
            +L+D      C+P+++CPC++   +  PG    +  C  C C  G  +C    CP  C
Sbjct: 2663 LLHDT----RCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCEKGELLCQPGGCPLPC 2716



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 36/102 (35%), Positives = 46/102 (45%), Gaps = 15/102 (14%)

Query: 763  SCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTK-CEPGCVCAEGLYENADGQC 821
            SC  P  F +C        G+ CA  C    +   C     C+PGC C +GL E A G C
Sbjct: 4422 SCTPPFEFHAC--------GSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGLLEQAGG-C 4472

Query: 822  VPPEECPC-----EFSGVSYPGGAELHTDCRTCSCSRGRWAC 858
            +PPEEC C       +G++   G  L   C+ C C RG   C
Sbjct: 4473 IPPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHC 4514



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 54/186 (29%), Positives = 73/186 (39%), Gaps = 36/186 (19%)

Query: 229  ARICTQLLTLVAPECS----VSKEPFVLSCQAD----------VAAAPQPGP--QNSSCA 272
            +R C+ L  LV   C      S+  F  +C  D          V + P  G   +   C 
Sbjct: 1718 SRRCSPLGLLVLQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCH 1777

Query: 273  TLSEYSRQCSMVGQPVRRWRSPGLCSVGQCP-----ANQVYQECGSACVKTCSN------ 321
            +     R C+ +   +   R    C    CP        ++Q C + C  TC +      
Sbjct: 1778 SPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPC-APCPLTCDDISGQVT 1836

Query: 322  --PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTC 379
              P   C S    GC+CPEG VL    +   CV   QCPC++ GA Y PG+   A CQ C
Sbjct: 1837 CPPDWPCGSP---GCWCPEGQVLG---SEGWCVWPRQCPCLVDGARYWPGQRIKADCQLC 1890

Query: 380  RCTLGR 385
             C  GR
Sbjct: 1891 ICQDGR 1896



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 70/283 (24%), Positives = 96/283 (33%), Gaps = 90/283 (31%)

Query: 660  CTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDG-CNCPDGTYLNQKGECVRK 718
            CT  C G  +     Q C R+C  LS  +  C   +V     C CP G  L+Q G CV  
Sbjct: 3526 CT-DCGGGQSLHPCGQPCPRSCQDLSPGSV-CQPGSVGCQPTCGCPLGQ-LSQDGLCVPP 3582

Query: 719  AQCPCILE--------------GYKFIL---AEQSTVINGI--TCHCINGRLSCPQRP-- 757
            A C C  +              G +F      E   V+ G    C C+ G L C + P  
Sbjct: 3583 AHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDC 3642

Query: 758  -----------------------QMFLASCQAP------KTFKSCSQS------------ 776
                                   Q+    C  P      +  ++CS              
Sbjct: 3643 PDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQVCREAGCPAGRL 3702

Query: 777  -SENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSG-- 833
              E + G  C  +C  +   V C    CE GC C EG +++    CV  +ECPC  +   
Sbjct: 3703 YRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLA-CV--QECPCVLTAWL 3759

Query: 834  -------VSYPG-----------GAELHTDCRTCSCSRGRWAC 858
                   +  PG           G  L T C  CSC+ G+ +C
Sbjct: 3760 LQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSC 3802



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 53/182 (29%), Positives = 72/182 (39%), Gaps = 46/182 (25%)

Query: 251  VLSCQADVAAAPQPGPQNS---------SCATLSEY-SRQCSM--VGQPVRRWR--SPGL 296
            +L CQ +V   P PG  +S         SC    +  SR+C+      P R+ R  S  +
Sbjct: 3633 ILQCQ-EVPDCPDPGVWSSWGPWEDCSVSCGGGEQLRSRRCARPPCPGPARQSRTCSTQV 3691

Query: 297  CSVGQCPANQVYQEC--GSACVKTCSN--PQHSC-SSSCTFGCFCPEGTVLNDLSNNHTC 351
            C    CPA ++Y+EC  G  C  +C++   Q  C S  C  GC CPEGT        H  
Sbjct: 3692 CREAGCPAGRLYRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTF------QHRL 3745

Query: 352  VPVTQCPCVL--------------------HGAMYAPGEVTIAACQTCRCTLGRWVCTER 391
              V +CPCVL                     G     G+    +C  C C  G+  C+  
Sbjct: 3746 ACVQECPCVLTAWLLQELGATIGDPGQPLGPGDELDSGQTLRTSCGNCSCAHGKLSCSLD 3805

Query: 392  PC 393
             C
Sbjct: 3806 DC 3807



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 34/109 (31%), Positives = 43/109 (39%), Gaps = 20/109 (18%)

Query: 301  QCPANQVYQECGSACVKTCSNPQHSC---SSSCTFGCFCPEGTVLNDLSNNHTCVPVTQC 357
            +CP  QV   C ++C   C + Q         C  GC CP G +L+    N TCVP T C
Sbjct: 4817 ECPPGQVLSACATSCPCLCWHLQPGAICVQEPCQPGCGCPGGQLLH----NGTCVPPTAC 4872

Query: 358  PCVLHGAMYA-------------PGEVTIAACQTCRCTLGRWVCTERPC 393
            PC  H   +              PG V    C  C C  G + C+   C
Sbjct: 4873 PCTQHSLPWGLTLTLEEQAQELPPGTVLTRNCTRCVCHGGAFSCSLVDC 4921



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 14/113 (12%)

Query: 297  CSVGQC--PANQVYQECGSA----CVKTC-----SNPQHSCSSSCTFGCFCPEGTVLNDL 345
            CS+  C  P  + +Q+        C +TC     +  Q +CSS+   GC C  G   +  
Sbjct: 4916 CSLVDCQVPPGETWQQVAPGELGLCEQTCLEMNATKTQSNCSSARASGCVCQPG---HFR 4972

Query: 346  SNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPGHCS 398
            S    CVP   C C   G  + PG     AC++C C  GR VCT+   P  C+
Sbjct: 4973 SQAGPCVPEDHCECWHLGRPHLPGSEWQEACESCLCLSGRPVCTQHCSPLTCA 5025



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 39/139 (28%), Positives = 59/139 (42%), Gaps = 16/139 (11%)

Query: 660  CTIPCTGNTTFSYNSQA------CERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKG 713
            CT  C  N  F    Q       C R CL+      EC     P  GC CP G +L+   
Sbjct: 2882 CTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGP-GIECTGFCAP--GCTCPPGLFLHN-A 2937

Query: 714  ECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTF--- 770
             C+ ++QCPC L G  +     + + +   C C++G+++C    +  +A   +P T    
Sbjct: 2938 SCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSE-RCPVACGWSPWTLWSL 2996

Query: 771  --KSCSQSSENKFGAACAP 787
               SC+     +F A  AP
Sbjct: 2997 CSCSCNVGIRRRFRAGTAP 3015



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 32/104 (30%), Positives = 42/104 (40%), Gaps = 17/104 (16%)

Query: 764  CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
            C   K +  C+Q       A+CA       T   C      PGC C  G+    +  CVP
Sbjct: 3090 CPRDKQWLDCAQGP-----ASCAELSAPRGTNQTC-----HPGCHCPSGMLL-LNNVCVP 3138

Query: 824  PEECPCEFSGVSYPGGAELHTDCRTCSCSRG------RWACQQG 861
             ++CPC   G  YP G+ +   C  CSC  G       W C +G
Sbjct: 3139 TQDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANCSSWPCAEG 3182



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 23/136 (16%)

Query: 748  NGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAA--------------CAPTCQMLA 793
            NG   CP   Q      +AP   + CS  ++ + G                C P+C    
Sbjct: 2589 NGGAPCPGASQE-----RAPCGLQPCSGGTDCELGRVYVSADLCQKGLVPPCPPSCLDPK 2643

Query: 794  TGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSG-VSYPGGAELHTDCRTCSCS 852
               +C    C  GC C  GL  + D +C+P  ECPC     + +PG + L  +C  C C 
Sbjct: 2644 ANRSC-SGHCVEGCRCPPGLLLH-DTRCLPLSECPCLVGEELKWPGVSFLLGNCSQCVCE 2701

Query: 853  RGRWACQQGTHCPSTC 868
            +G   CQ G  CP  C
Sbjct: 2702 KGELLCQPG-GCPLPC 2716



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 32/108 (29%), Positives = 41/108 (37%), Gaps = 13/108 (12%)

Query: 297  CSVGQCPANQVYQECGSACVKTCSN--PQHSCSS--SCTFGCFCPEGTVLNDLSNNHTCV 352
            CS   C     +  CGS C   C+       C     C  GC+CP+G     L     C+
Sbjct: 4418 CSEDSCTPPFEFHACGSPCAGLCATHLSHQLCQDLPPCQPGCYCPKGL----LEQAGGCI 4473

Query: 353  PVTQCPC-----VLHGAMYAPGEVTIAACQTCRCTLGRWVCTERPCPG 395
            P  +C C        G   APG+     C+ C C  G   CT + C G
Sbjct: 4474 PPEECNCWHTSAAGAGMTLAPGDRLQLGCKECECRRGELHCTSQGCQG 4521



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 8/87 (9%)

Query: 785  CAPTCQMLATGVACVPTK-CEPGCVCAEGLYENADGQCVPPEECPC-EFSGVSYPGGAEL 842
            C   C  L  G+ C   + C+ GC C +G  E  DG CVP   C C +  G S+  G++ 
Sbjct: 4075 CPRRCSDLQEGIVCQDDQVCQKGCRCPKGSLEQ-DGGCVPIGHCDCTDAQGHSWAPGSQH 4133

Query: 843  HTDCRTCSCSRGRWA-----CQQGTHC 864
               C  CSC  G+ +     C   THC
Sbjct: 4134 QDACNNCSCQAGQLSCTAQPCPPPTHC 4160



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 32/110 (29%), Positives = 46/110 (41%), Gaps = 16/110 (14%)

Query: 297  CSVGQCPANQVYQ-----ECGSACVKTCSN--PQHSC-SSSCTFGCFCPEGTVLNDLSNN 348
            C+ G CP  +        +C + C  +C++   +  C    C  GC CP G ++ D    
Sbjct: 4659 CNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQD---- 4714

Query: 349  HTCVPVTQCPCVLHGAM----YAPGEVTIAACQTCRCTLGRWVCTERPCP 394
              CVP++ C C L  A      AP +     CQ C C     VC  + CP
Sbjct: 4715 GRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECP 4764



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 74/329 (22%), Positives = 105/329 (31%), Gaps = 80/329 (24%)

Query: 580  MSQLNKVCAET-HCSML-LRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALG 637
            +S    +C +  HCS L L TG   +R H      P  +      CN+       C  L 
Sbjct: 3352 LSSNGAICVQPGHCSCLDLLTG---QRHH------PGARLARPDGCNH-------CTCLE 3395

Query: 638  DYVHACSLRGVLLWGWR--SSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSA 695
              ++   L   +  GW   S    C+ PC G T     + AC               H  
Sbjct: 3396 GRLNCTDLPCPVPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTP-----------QHGG 3444

Query: 696  VPVDGCNCPDGTYLNQKGECVRKAQCP----------------CILEGYKF-ILAEQSTV 738
             P  G    +    +Q+  C   A CP                C+ + ++    +   T 
Sbjct: 3445 APCTG-EAGEAGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTP 3503

Query: 739  INGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVAC 798
              G  C   + +    Q        C   ++   C Q         C  +CQ L+ G  C
Sbjct: 3504 EGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHPCGQP--------CPRSCQDLSPGSVC 3555

Query: 799  VPTK--CEPGCVCAEGLYENADGQCVPPEECPCEF--------------------SGVSY 836
             P    C+P C C  G     DG CVPP  C C++                    S  S 
Sbjct: 3556 QPGSVGCQPTCGCPLGQLSQ-DGLCVPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESL 3614

Query: 837  PGGAELHTDCRTCSCSRGRWACQQGTHCP 865
              G  +   C  C+C  G   CQ+   CP
Sbjct: 3615 EPGEVVTGPCDNCTCVAGILQCQEVPDCP 3643



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 52/184 (28%), Positives = 59/184 (32%), Gaps = 42/184 (22%)

Query: 249  PFVLSCQADVAAAPQ-PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQ------ 301
            P   +C  D A  P  P      C   S  SR CS    P      PG  +  +      
Sbjct: 3464 PSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENS 3523

Query: 302  -----CPANQVYQECGSACVKTCSN--PQHSC---SSSCTFGCFCPEGTVLNDLSNNHTC 351
                 C   Q    CG  C ++C +  P   C   S  C   C CP    L  LS +  C
Sbjct: 3524 TQCTDCGGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCP----LGQLSQDGLC 3579

Query: 352  VPVTQCPCVLH-GAM-------------------YAPGEVTIAACQTCRCTLGRWVCTER 391
            VP   C C    GAM                     PGEV    C  C C  G   C E 
Sbjct: 3580 VPPAHCRCQYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEV 3639

Query: 392  P-CP 394
            P CP
Sbjct: 3640 PDCP 3643



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 55/219 (25%), Positives = 75/219 (34%), Gaps = 24/219 (10%)

Query: 660  CTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKA 719
            C   C         +  C R C  L +    C    V   GC CP G+ L Q G CV   
Sbjct: 4058 CEAGCPAGMEVVTCANRCPRRCSDLQEGIV-CQDDQVCQKGCRCPKGS-LEQDGGCVPIG 4115

Query: 720  QCPCI-LEGYKFILAEQ-STVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSS 777
             C C   +G+ +    Q     N   C C  G+LSC  +P      C  P        S+
Sbjct: 4116 HCDCTDAQGHSWAPGSQHQDACN--NCSCQAGQLSCTAQP------CPPPTHCAWSHWSA 4167

Query: 778  ENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECP---CEFSGV 834
             +    +C P  Q               G    E   E +  Q  P   CP    + +  
Sbjct: 4168 WSPCSHSCGPRGQQSRF------RSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRS 4221

Query: 835  SYPGGAELHTDCRTCSCSRGRWACQQGTHC--PSTCTLY 871
               G + L  +C+ CSC+     C+  T C  P   TL+
Sbjct: 4222 RTLGDSWLQGECQRCSCTPEGVICED-TECAVPEAWTLW 4259



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 65/248 (26%), Positives = 83/248 (33%), Gaps = 34/248 (13%)

Query: 636  LGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSA 695
            LGDY      +G +       V NCT        +S     C R+C  L      C    
Sbjct: 3287 LGDYCEGPRAQGEVCQALPCPVTNCT--AIEGAEYSPCGPPCPRSCDDLVHCVWRCQ--- 3341

Query: 696  VPVDGCNCPDGTYLNQKGE-CVRKAQCPCI--LEGYKFILAEQSTVINGIT-CHCINGRL 751
                GC CP G  L+  G  CV+   C C+  L G +     +    +G   C C+ GRL
Sbjct: 3342 ---PGCYCPPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRL 3398

Query: 752  SCPQRPQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAE 811
            +C   P      C  P  +  C  S        C    +  +   AC PT    G  C  
Sbjct: 3399 NCTDLP------CPVPGGW--CPWSEWTMCSQPCRGQTRSRSRACAC-PTPQHGGAPCTG 3449

Query: 812  GLYENADGQCVPPEECP----CEFSGVSYPGGAELHTDC------RTCSCSRGRWACQQG 861
               E   G     E CP    C   G   P G     D       R+ +CSR     + G
Sbjct: 3450 EAGE--AGAQHQREACPSYATCPVDGAWGPWGPWSPCDMCLGQSHRSRACSRPP-TPEGG 3506

Query: 862  THCPSTCT 869
              CP   T
Sbjct: 3507 RPCPGNHT 3514



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 17/117 (14%)

Query: 764  CQAPKTFKSCS-------QSSENKFGAACAP----TCQMLATGVACVPTKCEPGCVCAEG 812
            C+ P   +SC+       ++ +  F   CA     +C  L   V C+   C PGC C  G
Sbjct: 4650 CREPWAQESCNGGPCPECEAQDTVFTLDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPG 4709

Query: 813  LYENADGQCVPPEECPCEFSGVS----YPGGAELHTDCRTCSCSRGRWACQQGTHCP 865
                 DG+CVP   C C     +          +  DC+ C+C      C     CP
Sbjct: 4710 QLVQ-DGRCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPH-QECP 4764



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 41/149 (27%), Positives = 59/149 (39%), Gaps = 25/149 (16%)

Query: 700  GCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGI-TCHCINGRL-SCPQRP 757
            GC+CP G  L     CV    CPC  EG+  +    STV+     C C++G + +C   P
Sbjct: 3122 GCHCPSGMLL-LNNVCVPTQDCPCAHEGH--LYPPGSTVVRPCENCSCVSGLIANCSSWP 3178

Query: 758  QMFLASCQAPKT-FKSCSQS------SENKFGAACAPTCQMLATGVACVPTKCEPGCVCA 810
                    +P T +  CS S        ++F   CA +   + + VA +P    P  +C+
Sbjct: 3179 CAEGEPTWSPWTPWSQCSASCGPARCHRHRF---CARSPSAVPSTVAPLPLPATPTPLCS 3235

Query: 811  EGLYENADGQCVPPEECPCEFSGVSYPGG 839
                          EE PC   G    GG
Sbjct: 3236 G----------PEAEEEPCLLQGCDRAGG 3254



 Score = 35.8 bits (81), Expect = 0.53
 Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 16/83 (19%)

Query: 677  CERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCIL------EGYKF 730
            C  +CL      +   H    V+GC CP G  L+    C+  ++CPC++       G  F
Sbjct: 2635 CPPSCLDPKANRSCSGHC---VEGCRCPPGLLLHDT-RCLPLSECPCLVGEELKWPGVSF 2690

Query: 731  ILAEQSTVINGITCHCINGRLSC 753
            +L       N   C C  G L C
Sbjct: 2691 LLG------NCSQCVCEKGELLC 2707



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 38/156 (24%), Positives = 52/156 (33%), Gaps = 13/156 (8%)

Query: 1162 CPSQPQSVPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPTTPQPPTTPQLPTTGSRPTQV- 1220
            C S    + G   +G  +C        EEG CV     T     T   L  + ++P Q+ 
Sbjct: 2241 CASGECVLRGGPCDGVLDCEDGS---DEEG-CVLLPEGTGRFHSTAKTLALSSAQPGQLL 2296

Query: 1221 -WPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVT 1279
             WP  G       L+ T   P    +P SPT+T  +     S  P          TT + 
Sbjct: 2297 HWPREG-------LAETEHWPPGQESPTSPTETRPVSPGPASGVPHHGESVQMVTTTPIP 2349

Query: 1280 PQATSGLPPTATLRSTATKPTVTQATTRATASTASP 1315
                  LPP     +      VT AT    +    P
Sbjct: 2350 QMEARTLPPGMAAVTVVPPHPVTPATPAGQSVAPGP 2385


>gi|239755901 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  447 bits (1150), Expect = e-125
 Identities = 313/1142 (27%), Positives = 505/1142 (44%), Gaps = 117/1142 (10%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPD--GSISRIIVE 100
            G C TWG  HF TFD   Y F G C+YIFA  C D  P ++V +   P   GS+      
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRS 121

Query: 101  LGASVVTVSEAII---SVKDIGV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +        E  I    +K  G+ ++LP T   + I      + +   +      + W  
Sbjct: 122  ISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILV---KTTFGFSLAWDG 178

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAA----LQKLDDPGEI 212
             S + + +   + G+ CGLCGN++   +++F+  +  + E     A    +Q  DD   +
Sbjct: 179  ISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCV 238

Query: 213  CTFQDIPS--THVRQAQHARI--CTQLLTLVAPECSVSKEPF--VLSCQADVAAAPQPGP 266
             T  D P+  +    A  A    C  LL      C    +P+  + SC  D+        
Sbjct: 239  LTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDD--- 295

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSC 326
              + C   +EY+R CS  G P++ WR        +C  + V+++C S C  TC+  +   
Sbjct: 296  DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCL 355

Query: 327  SSS--CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLG 384
             S+  C  GC+CP+G V++    N TC+ +  CPC  HG  Y+ G      C  C C  G
Sbjct: 356  GSNLHCLDGCYCPDGLVMD----NGTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGG 411

Query: 385  RWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSP----------QLPEDGA 434
             W CTE+ CP  CS+ G S  TTFD R Y F G C YIL++            + P +  
Sbjct: 412  VWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQN 471

Query: 435  LMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTS 494
            L  V  +S     E      V L R  +I+ S ++    NG           + +   +S
Sbjct: 472  LGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI----------VEIQTLSS 521

Query: 495  THLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGT 554
              + + T+FGL+++  +    + Y+ +   ++ +T GLCG FNG+  DDF +  G+ EGT
Sbjct: 522  LFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGT 580

Query: 555  ASLFVDSWRAGN-CPAALERET-DPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPA 612
              L  ++WR  + C A +     DPC+++Q N +    HC ++ +   +F  CH  ++P 
Sbjct: 581  PQLHANAWRVSSTCFAPVHVPVVDPCNINQQN-IGYAAHCDVIHQE--LFAPCHIYISPG 637

Query: 613  PFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSY 672
             +Y+ C + AC    +   +C AL  Y + C   GV +  +R+ +  C + C     + +
Sbjct: 638  LYYQLCRHDACKCGSSC--LCNALAHYAYLCGQHGVPI-DFRTQISFCAVVCQKGMLYHH 694

Query: 673  NSQACERTCLSLSDRATECHHSAVPVDGCNCPDGT-YLNQKGECVRKAQCPCILEGYKFI 731
             S  C  +C+SLS    +C       +GCNCP+G  Y +    CV    C C   G  + 
Sbjct: 695  CSSFCLHSCISLSS-PEQCSDDCA--EGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQ 751

Query: 732  LAEQSTVINGITCHCINGRLSCPQ-RPQMFLASCQAPKTFKSCSQSSEN--KFGAACAPT 788
              E     +G+ C C NG + C +      +  C   K +  C          G  C  T
Sbjct: 752  PGELIPTPSGL-CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETT 810

Query: 789  CQMLATGVACVPTK-CEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCR 847
            C  LA    C P+  C  GCVCA G+                                  
Sbjct: 811  CANLAMNFTCTPSSPCISGCVCAPGV---------------------------------- 836

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
               C RG + C     CP+ CT+YG+ H  +FDG  + +  +C+  L   +   +DS   
Sbjct: 837  ---CRRGMFNCTYYP-CPAVCTIYGDRHYYSFDGLEYDYISDCQVFL---IKSADDSD-- 887

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGA--LSLV 965
              ++ +N  C ++ + CS+++ I +G   + L D  Y        ++   T         
Sbjct: 888  ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYY 947

Query: 966  VDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSEL 1025
            + +  P + ++T++W+R  TI I++    ++ L GLCGNF+    +D  T +     +  
Sbjct: 948  IVVYFPEK-DITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR 1006

Query: 1026 ELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEAC 1085
               +SW     C        PC  +  +  +A+++CS++ S  FA+C + +    + + C
Sbjct: 1007 VFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNC 1065

Query: 1086 VRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEY 1145
              D C C+ GGDCECLC ++AAYA  C  +G+ + WR+   C + C +YN    +G GE 
Sbjct: 1066 HEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN----EGLGEG 1121

Query: 1146 QY 1147
             Y
Sbjct: 1122 PY 1123



 Score =  110 bits (276), Expect = 1e-23
 Identities = 107/434 (24%), Positives = 164/434 (37%), Gaps = 35/434 (8%)

Query: 331 TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTE 390
           TF  F P G+   +  N   C     C C +  A+              RC +   +   
Sbjct: 12  TFFFFSPSGSCPYECLNGAFCSKTGTCDCQIFQAL------------GTRCQIIPNMGNG 59

Query: 391 RPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETS 450
           R   G C   G     TFD   Y F G C+YI  +     E    + V++      S  S
Sbjct: 60  R--DGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYS 117

Query: 451 LVAVV--YLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELV 508
               +  + S Q++I I   E +  NG +  LP     I +  + + ++ + T+FG  L 
Sbjct: 118 CYRSISLFFSNQEEIRIYGHE-IKKNGISLTLPQTIGQIFI-EKLADYILVKTTFGFSLA 175

Query: 509 VQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA---- 564
                I   Y+ +    +G++ GLCGN+N   +DDF           ++F +SW      
Sbjct: 176 WD--GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233

Query: 565 -GNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQAC 623
              C        +PCS            C +LL+    F  CH  ++P  +   CV   C
Sbjct: 234 DTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQ--FPFLSCHEYIDPYLYIASCVNDLC 291

Query: 624 NYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLS 683
             ++   + C A  +Y  ACS  G  +  WR     CT  C  +         C  TC  
Sbjct: 292 KTDDDETY-CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF 350

Query: 684 LSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGIT 743
                    H    +DGC CPDG  ++  G C+    CPC   G  + +   S +    T
Sbjct: 351 EKQCLGSNLHC---LDGCYCPDGLVMD-NGTCISLENCPCGFHGLAYSVG--SKIEQECT 404

Query: 744 -CHCINGRLSCPQR 756
            C C+ G  +C ++
Sbjct: 405 ECVCVGGVWNCTEQ 418



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 83/353 (23%), Positives = 148/353 (41%), Gaps = 38/353 (10%)

Query: 388  CTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHS 447
            C E  CP  CS+     + TFD      +   +YIL++ P       ++A  +K  ++ +
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIP----GEIIVAHIEKCSMNQA 1487

Query: 448  ETSLVAVVYLSRQD------KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMA 500
             +  ++ +   + +      KI++++    V  +     LP+ ++ +++    S ++ + 
Sbjct: 1488 PSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-IT 1546

Query: 501  TSFGLELV-VQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIA---EGTAS 556
            T  GL +    L  I   +          T GLCG  N D  DD     G          
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 557  LFVDSWRAGNCPAALERETDPCSMSQLNKVCAETHCSML--LRTGTVFERCHATVNPAPF 614
            LF++SW        +E+  +  +M +  + C E  CS    L    +F  CH  V+P  F
Sbjct: 1607 LFIESWE-------IEKSFE-VTMRRPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDF 1658

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
               C     NY   + + C AL  YV  C+   + +  WR+  D C++ C     +    
Sbjct: 1659 ---CEKMWINYTYFWNYECDALSAYVALCNKFDICI-QWRTP-DYCSLSCPEGKEYQPCV 1713

Query: 675  QACE-RTCLSLSDRATECHHSAVPV-DGCNCPDGTYLNQ--KGECVRKAQCPC 723
            + CE RTCL   ++    H S + + + C C  GT L++    +C+ + +C C
Sbjct: 1714 RPCEARTCL---NQWFYGHTSCLNLREDCVCKVGTVLHRPHSAQCIPEKECAC 1763



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 95/425 (22%), Positives = 160/425 (37%), Gaps = 95/425 (22%)

Query: 794  TGVACVPTKCEPGCVCAEGLYENADGQ-------CVPPEECP-CEFSGVSYPGGAELHTD 845
            TG+ C P K +P   C++ +  N + Q       C    E P C F G      +++   
Sbjct: 1374 TGLECEPQKFDPVYDCSQYICLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDI--- 1430

Query: 846  CRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILAT--------- 896
                        C     CP  C++  E  +ITFDG          YIL           
Sbjct: 1431 ------------CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAH 1478

Query: 897  -DVCGVNDSQP------TFKILTENVICGNSGVTCSR-AIKIFLGGLSVVLADRNYTVTG 948
             + C +N +         FK L  NV      +  +R A K+ +  + V L   +  ++ 
Sbjct: 1479 IEKCSMNQAPSGRISGLCFKKL--NVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSI 1536

Query: 949  EEPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGN 1008
            E+      +T  A  L++  S     +LT I + H      ++  ++    GLCG  N +
Sbjct: 1537 EDSGSMYVITTPA-GLIIKWS-----HLTGIIDIHFGFRFNLSSYTE----GLCGICNED 1586

Query: 1009 MKDDFETRSRYVASSELEL---VNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCS--- 1062
              DD   ++  + ++  ++   + SW+      + SF     ++    R+  E  CS   
Sbjct: 1587 PDDDLRMQNGTIITNMEDIGLFIESWEI-----EKSFEV---TMRRPVRNCTEHDCSQCI 1638

Query: 1063 -VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDW 1121
             ++N + F  CH KV    +   C +         + EC  DA++AY   C    +C+ W
Sbjct: 1639 DLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQW 1693

Query: 1122 RTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEG---CY 1178
            RTP +C + C        +G               YQPC+ P + ++       G   C 
Sbjct: 1694 RTPDYCSLSC-------PEGK-------------EYQPCVRPCEARTCLNQWFYGHTSCL 1733

Query: 1179 NCSQD 1183
            N  +D
Sbjct: 1734 NLRED 1738



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 50/269 (18%), Positives = 107/269 (39%), Gaps = 16/269 (5%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSI---SR 96
            P    C+ +G  H+ +FD   YD+   C      +  D+  +   Q ++  D  I     
Sbjct: 848  PCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKS 907

Query: 97   IIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +++ +G + + +++     K  G     +  N      +     +V    E ++ ++W  
Sbjct: 908  VLISVGDTEIYLNDTPYKQKQSGF----FLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFA----ALQKLDDPGEI 212
             + + + V  ++  ++ GLCGNFD   +N+  +     +   +      AL + + P E 
Sbjct: 964  KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDE- 1022

Query: 213  CTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQNSS 270
             T +   +   +     + C+ L + +   C   +    F  +C  D       G     
Sbjct: 1023 -TIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081

Query: 271  CATLSEYSRQCSMVGQPVRRWRSPGLCSV 299
            C +++ Y+ +C   G  +  WRS  +CS+
Sbjct: 1082 CTSIAAYAYKCCQEGISI-HWRSSTVCSL 1109



 Score = 38.5 bits (88), Expect = 0.082
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 15/98 (15%)

Query: 2347 GVCSVREQQEEITFK----------GCMAN--VTVTRCEGACISAASFNIITQQVDARCS 2394
            G C + +++E I  K           CM+   + V  C+G C SA  +NI  +     C 
Sbjct: 2153 GCCKICKREERICQKVIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCK 2212

Query: 2395 CCRPLHSYEQQLELPCPDPSTPGRRLVLTLQVFSHCVC 2432
            CCR        + L C   S  G  ++ TLQ    C C
Sbjct: 2213 CCRENGVRNLSVPLYC---SGNGTEIMYTLQEPIDCTC 2247



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 23/102 (22%)

Query: 1153 CTWHYQPCLCP-----SQPQSVPGS---NIEGCY-NCSQDEYFDHEEGVCV---PCMP-- 1198
            C W Y+PC  P     S P+++       +EGC   C ++   D     CV    C+P  
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVI 1336

Query: 1199 PTTP--QPPTTPQLPTTGSRPTQVWPMTGTS--TTIGLLSST 1236
            PT P   PP  P +P        VW M   S  T   +L+ T
Sbjct: 1337 PTEPTLMPPAKPTVPM-----FTVWEMITPSDITVFDMLTPT 1373


>gi|239750386 PREDICTED: chromosome 12 open reading frame 64 [Homo
            sapiens]
          Length = 2250

 Score =  447 bits (1150), Expect = e-125
 Identities = 313/1142 (27%), Positives = 505/1142 (44%), Gaps = 117/1142 (10%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPD--GSISRIIVE 100
            G C TWG  HF TFD   Y F G C+YIFA  C D  P ++V +   P   GS+      
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRS 121

Query: 101  LGASVVTVSEAII---SVKDIGV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +        E  I    +K  G+ ++LP T   + I      + +   +      + W  
Sbjct: 122  ISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILV---KTTFGFSLAWDG 178

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAA----LQKLDDPGEI 212
             S + + +   + G+ CGLCGN++   +++F+  +  + E     A    +Q  DD   +
Sbjct: 179  ISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCV 238

Query: 213  CTFQDIPS--THVRQAQHARI--CTQLLTLVAPECSVSKEPF--VLSCQADVAAAPQPGP 266
             T  D P+  +    A  A    C  LL      C    +P+  + SC  D+        
Sbjct: 239  LTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDD--- 295

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSC 326
              + C   +EY+R CS  G P++ WR        +C  + V+++C S C  TC+  +   
Sbjct: 296  DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCL 355

Query: 327  SSS--CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLG 384
             S+  C  GC+CP+G V++    N TC+ +  CPC  HG  Y+ G      C  C C  G
Sbjct: 356  GSNLHCLDGCYCPDGLVMD----NGTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGG 411

Query: 385  RWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSP----------QLPEDGA 434
             W CTE+ CP  CS+ G S  TTFD R Y F G C YIL++            + P +  
Sbjct: 412  VWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQN 471

Query: 435  LMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTS 494
            L  V  +S     E      V L R  +I+ S ++    NG           + +   +S
Sbjct: 472  LGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI----------VEIQTLSS 521

Query: 495  THLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGT 554
              + + T+FGL+++  +    + Y+ +   ++ +T GLCG FNG+  DDF +  G+ EGT
Sbjct: 522  LFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGT 580

Query: 555  ASLFVDSWRAGN-CPAALERET-DPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPA 612
              L  ++WR  + C A +     DPC+++Q N +    HC ++ +   +F  CH  ++P 
Sbjct: 581  PQLHANAWRVSSTCFAPVHVPVVDPCNINQQN-IGYAAHCDVIHQE--LFAPCHIYISPG 637

Query: 613  PFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSY 672
             +Y+ C + AC    +   +C AL  Y + C   GV +  +R+ +  C + C     + +
Sbjct: 638  LYYQLCRHDACKCGSSC--LCNALAHYAYLCGQHGVPI-DFRTQISFCAVVCQKGMLYHH 694

Query: 673  NSQACERTCLSLSDRATECHHSAVPVDGCNCPDGT-YLNQKGECVRKAQCPCILEGYKFI 731
             S  C  +C+SLS    +C       +GCNCP+G  Y +    CV    C C   G  + 
Sbjct: 695  CSSFCLHSCISLSS-PEQCSDDCA--EGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQ 751

Query: 732  LAEQSTVINGITCHCINGRLSCPQ-RPQMFLASCQAPKTFKSCSQSSEN--KFGAACAPT 788
              E     +G+ C C NG + C +      +  C   K +  C          G  C  T
Sbjct: 752  PGELIPTPSGL-CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETT 810

Query: 789  CQMLATGVACVPTK-CEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCR 847
            C  LA    C P+  C  GCVCA G+                                  
Sbjct: 811  CANLAMNFTCTPSSPCISGCVCAPGV---------------------------------- 836

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
               C RG + C     CP+ CT+YG+ H  +FDG  + +  +C+  L   +   +DS   
Sbjct: 837  ---CRRGMFNCTYYP-CPAVCTIYGDRHYYSFDGLEYDYISDCQVFL---IKSADDSD-- 887

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGA--LSLV 965
              ++ +N  C ++ + CS+++ I +G   + L D  Y        ++   T         
Sbjct: 888  ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYY 947

Query: 966  VDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSEL 1025
            + +  P + ++T++W+R  TI I++    ++ L GLCGNF+    +D  T +     +  
Sbjct: 948  IVVYFPEK-DITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR 1006

Query: 1026 ELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEAC 1085
               +SW     C        PC  +  +  +A+++CS++ S  FA+C + +    + + C
Sbjct: 1007 VFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNC 1065

Query: 1086 VRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEY 1145
              D C C+ GGDCECLC ++AAYA  C  +G+ + WR+   C + C +YN    +G GE 
Sbjct: 1066 HEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN----EGLGEG 1121

Query: 1146 QY 1147
             Y
Sbjct: 1122 PY 1123



 Score =  110 bits (276), Expect = 1e-23
 Identities = 107/434 (24%), Positives = 164/434 (37%), Gaps = 35/434 (8%)

Query: 331 TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTE 390
           TF  F P G+   +  N   C     C C +  A+              RC +   +   
Sbjct: 12  TFFFFSPSGSCPYECLNGAFCSKTGTCDCQIFQAL------------GTRCQIIPNMGNG 59

Query: 391 RPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETS 450
           R   G C   G     TFD   Y F G C+YI  +     E    + V++      S  S
Sbjct: 60  R--DGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYS 117

Query: 451 LVAVV--YLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELV 508
               +  + S Q++I I   E +  NG +  LP     I +  + + ++ + T+FG  L 
Sbjct: 118 CYRSISLFFSNQEEIRIYGHE-IKKNGISLTLPQTIGQIFI-EKLADYILVKTTFGFSLA 175

Query: 509 VQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA---- 564
                I   Y+ +    +G++ GLCGN+N   +DDF           ++F +SW      
Sbjct: 176 WD--GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233

Query: 565 -GNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQAC 623
              C        +PCS            C +LL+    F  CH  ++P  +   CV   C
Sbjct: 234 DTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQ--FPFLSCHEYIDPYLYIASCVNDLC 291

Query: 624 NYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLS 683
             ++   + C A  +Y  ACS  G  +  WR     CT  C  +         C  TC  
Sbjct: 292 KTDDDETY-CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF 350

Query: 684 LSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGIT 743
                    H    +DGC CPDG  ++  G C+    CPC   G  + +   S +    T
Sbjct: 351 EKQCLGSNLHC---LDGCYCPDGLVMD-NGTCISLENCPCGFHGLAYSVG--SKIEQECT 404

Query: 744 -CHCINGRLSCPQR 756
            C C+ G  +C ++
Sbjct: 405 ECVCVGGVWNCTEQ 418



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 83/353 (23%), Positives = 148/353 (41%), Gaps = 38/353 (10%)

Query: 388  CTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHS 447
            C E  CP  CS+     + TFD      +   +YIL++ P       ++A  +K  ++ +
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIP----GEIIVAHIEKCSMNQA 1487

Query: 448  ETSLVAVVYLSRQD------KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMA 500
             +  ++ +   + +      KI++++    V  +     LP+ ++ +++    S ++ + 
Sbjct: 1488 PSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-IT 1546

Query: 501  TSFGLELV-VQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIA---EGTAS 556
            T  GL +    L  I   +          T GLCG  N D  DD     G          
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 557  LFVDSWRAGNCPAALERETDPCSMSQLNKVCAETHCSML--LRTGTVFERCHATVNPAPF 614
            LF++SW        +E+  +  +M +  + C E  CS    L    +F  CH  V+P  F
Sbjct: 1607 LFIESWE-------IEKSFE-VTMRRPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDF 1658

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
               C     NY   + + C AL  YV  C+   + +  WR+  D C++ C     +    
Sbjct: 1659 ---CEKMWINYTYFWNYECDALSAYVALCNKFDICI-QWRTP-DYCSLSCPEGKEYQPCV 1713

Query: 675  QACE-RTCLSLSDRATECHHSAVPV-DGCNCPDGTYLNQ--KGECVRKAQCPC 723
            + CE RTCL   ++    H S + + + C C  GT L++    +C+ + +C C
Sbjct: 1714 RPCEARTCL---NQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 95/425 (22%), Positives = 160/425 (37%), Gaps = 95/425 (22%)

Query: 794  TGVACVPTKCEPGCVCAEGLYENADGQ-------CVPPEECP-CEFSGVSYPGGAELHTD 845
            TG+ C P K +P   C++ +  N + Q       C    E P C F G      +++   
Sbjct: 1374 TGLECEPQKFDPVYDCSQYICLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDI--- 1430

Query: 846  CRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILAT--------- 896
                        C     CP  C++  E  +ITFDG          YIL           
Sbjct: 1431 ------------CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAH 1478

Query: 897  -DVCGVNDSQP------TFKILTENVICGNSGVTCSR-AIKIFLGGLSVVLADRNYTVTG 948
             + C +N +         FK L  NV      +  +R A K+ +  + V L   +  ++ 
Sbjct: 1479 IEKCSMNQAPSGRISGLCFKKL--NVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSI 1536

Query: 949  EEPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGN 1008
            E+      +T  A  L++  S     +LT I + H      ++  ++    GLCG  N +
Sbjct: 1537 EDSGSMYVITTPA-GLIIKWS-----HLTGIIDIHFGFRFNLSSYTE----GLCGICNED 1586

Query: 1009 MKDDFETRSRYVASSELEL---VNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCS--- 1062
              DD   ++  + ++  ++   + SW+      + SF     ++    R+  E  CS   
Sbjct: 1587 PDDDLRMQNGTIITNMEDIGLFIESWEI-----EKSFEV---TMRRPVRNCTEHDCSQCI 1638

Query: 1063 -VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDW 1121
             ++N + F  CH KV    +   C +         + EC  DA++AY   C    +C+ W
Sbjct: 1639 DLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQW 1693

Query: 1122 RTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEG---CY 1178
            RTP +C + C        +G               YQPC+ P + ++       G   C 
Sbjct: 1694 RTPDYCSLSC-------PEGK-------------EYQPCVRPCEARTCLNQWFYGHTSCL 1733

Query: 1179 NCSQD 1183
            N  +D
Sbjct: 1734 NLRED 1738



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 50/269 (18%), Positives = 107/269 (39%), Gaps = 16/269 (5%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSI---SR 96
            P    C+ +G  H+ +FD   YD+   C      +  D+  +   Q ++  D  I     
Sbjct: 848  PCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKS 907

Query: 97   IIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +++ +G + + +++     K  G     +  N      +     +V    E ++ ++W  
Sbjct: 908  VLISVGDTEIYLNDTPYKQKQSGF----FLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFA----ALQKLDDPGEI 212
             + + + V  ++  ++ GLCGNFD   +N+  +     +   +      AL + + P E 
Sbjct: 964  KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDE- 1022

Query: 213  CTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQNSS 270
             T +   +   +     + C+ L + +   C   +    F  +C  D       G     
Sbjct: 1023 -TIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081

Query: 271  CATLSEYSRQCSMVGQPVRRWRSPGLCSV 299
            C +++ Y+ +C   G  +  WRS  +CS+
Sbjct: 1082 CTSIAAYAYKCCQEGISI-HWRSSTVCSL 1109



 Score = 38.5 bits (88), Expect = 0.082
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 15/98 (15%)

Query: 2347 GVCSVREQQEEITFK----------GCMAN--VTVTRCEGACISAASFNIITQQVDARCS 2394
            G C + +++E I  K           CM+   + V  C+G C SA  +NI  +     C 
Sbjct: 2153 GCCKICKREERICQKVIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCK 2212

Query: 2395 CCRPLHSYEQQLELPCPDPSTPGRRLVLTLQVFSHCVC 2432
            CCR        + L C   S  G  ++ TLQ    C C
Sbjct: 2213 CCRENGVRNLSVPLYC---SGNGTEIMYTLQEPIDCTC 2247



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 23/102 (22%)

Query: 1153 CTWHYQPCLCP-----SQPQSVPGS---NIEGCY-NCSQDEYFDHEEGVCV---PCMP-- 1198
            C W Y+PC  P     S P+++       +EGC   C ++   D     CV    C+P  
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVI 1336

Query: 1199 PTTP--QPPTTPQLPTTGSRPTQVWPMTGTS--TTIGLLSST 1236
            PT P   PP  P +P        VW M   S  T   +L+ T
Sbjct: 1337 PTEPTLMPPAKPTVPM-----FTVWEMITPSDITVFDMLTPT 1373


>gi|239744688 PREDICTED: hypothetical protein LOC283310 [Homo sapiens]
          Length = 2250

 Score =  447 bits (1150), Expect = e-125
 Identities = 313/1142 (27%), Positives = 505/1142 (44%), Gaps = 117/1142 (10%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPD--GSISRIIVE 100
            G C TWG  HF TFD   Y F G C+YIFA  C D  P ++V +   P   GS+      
Sbjct: 62   GICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYSCYRS 121

Query: 101  LGASVVTVSEAII---SVKDIGV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +        E  I    +K  G+ ++LP T   + I      + +   +      + W  
Sbjct: 122  ISLFFSNQEEIRIYGHEIKKNGISLTLPQTIGQIFIEKLADYILV---KTTFGFSLAWDG 178

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAA----LQKLDDPGEI 212
             S + + +   + G+ CGLCGN++   +++F+  +  + E     A    +Q  DD   +
Sbjct: 179  ISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPDDTKCV 238

Query: 213  CTFQDIPS--THVRQAQHARI--CTQLLTLVAPECSVSKEPF--VLSCQADVAAAPQPGP 266
             T  D P+  +    A  A    C  LL      C    +P+  + SC  D+        
Sbjct: 239  LTPSDFPNPCSSGMPAFEAIFFKCQILLQFPFLSCHEYIDPYLYIASCVNDLCKTDD--- 295

Query: 267  QNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQHSC 326
              + C   +EY+R CS  G P++ WR        +C  + V+++C S C  TC+  +   
Sbjct: 296  DETYCRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTFEKQCL 355

Query: 327  SSS--CTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLG 384
             S+  C  GC+CP+G V++    N TC+ +  CPC  HG  Y+ G      C  C C  G
Sbjct: 356  GSNLHCLDGCYCPDGLVMD----NGTCISLENCPCGFHGLAYSVGSKIEQECTECVCVGG 411

Query: 385  RWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSP----------QLPEDGA 434
             W CTE+ CP  CS+ G S  TTFD R Y F G C YIL++            + P +  
Sbjct: 412  VWNCTEQDCPVQCSVVGDSHFTTFDGRHYSFIGMCQYILVKGTGKDKFTITLQKAPCEQN 471

Query: 435  LMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTS 494
            L  V  +S     E      V L R  +I+ S ++    NG           + +   +S
Sbjct: 472  LGLVCLQSITLILEDDFNKQVTLGRGGQILTSPNQGFNLNGI----------VEIQTLSS 521

Query: 495  THLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGT 554
              + + T+FGL+++  +    + Y+ +   ++ +T GLCG FNG+  DDF +  G+ EGT
Sbjct: 522  LFILLKTTFGLKILFAIDGE-RIYIQLTSAWKRRTLGLCGTFNGNIRDDFLSPSGMIEGT 580

Query: 555  ASLFVDSWRAGN-CPAALERET-DPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPA 612
              L  ++WR  + C A +     DPC+++Q N +    HC ++ +   +F  CH  ++P 
Sbjct: 581  PQLHANAWRVSSTCFAPVHVPVVDPCNINQQN-IGYAAHCDVIHQE--LFAPCHIYISPG 637

Query: 613  PFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSY 672
             +Y+ C + AC    +   +C AL  Y + C   GV +  +R+ +  C + C     + +
Sbjct: 638  LYYQLCRHDACKCGSSC--LCNALAHYAYLCGQHGVPI-DFRTQISFCAVVCQKGMLYHH 694

Query: 673  NSQACERTCLSLSDRATECHHSAVPVDGCNCPDGT-YLNQKGECVRKAQCPCILEGYKFI 731
             S  C  +C+SLS    +C       +GCNCP+G  Y +    CV    C C   G  + 
Sbjct: 695  CSSFCLHSCISLSS-PEQCSDDCA--EGCNCPEGKFYEDTLNFCVPIFHCRCHYRGSVYQ 751

Query: 732  LAEQSTVINGITCHCINGRLSCPQ-RPQMFLASCQAPKTFKSCSQSSEN--KFGAACAPT 788
              E     +G+ C C NG + C +      +  C   K +  C          G  C  T
Sbjct: 752  PGELIPTPSGL-CQCSNGTVKCDELATPSAVHICPEGKEYFDCRFPDPELPAGGVNCETT 810

Query: 789  CQMLATGVACVPTK-CEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCR 847
            C  LA    C P+  C  GCVCA G+                                  
Sbjct: 811  CANLAMNFTCTPSSPCISGCVCAPGV---------------------------------- 836

Query: 848  TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPT 907
               C RG + C     CP+ CT+YG+ H  +FDG  + +  +C+  L   +   +DS   
Sbjct: 837  ---CRRGMFNCTYYP-CPAVCTIYGDRHYYSFDGLEYDYISDCQVFL---IKSADDSD-- 887

Query: 908  FKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGA--LSLV 965
              ++ +N  C ++ + CS+++ I +G   + L D  Y        ++   T         
Sbjct: 888  ISVIAQNKKCFDNDIVCSKSVLISVGDTEIYLNDTPYKQKQSGFFLENKSTYQLWKAGYY 947

Query: 966  VDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSEL 1025
            + +  P + ++T++W+R  TI I++    ++ L GLCGNF+    +D  T +     +  
Sbjct: 948  IVVYFPEK-DITILWDRKTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNAR 1006

Query: 1026 ELVNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEAC 1085
               +SW     C        PC  +  +  +A+++CS++ S  FA+C + +    + + C
Sbjct: 1007 VFGDSWALGQ-CESPDETIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNC 1065

Query: 1086 VRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEY 1145
              D C C+ GGDCECLC ++AAYA  C  +G+ + WR+   C + C +YN    +G GE 
Sbjct: 1066 HEDTCNCNLGGDCECLCTSIAAYAYKCCQEGISIHWRSSTVCSLDCEYYN----EGLGEG 1121

Query: 1146 QY 1147
             Y
Sbjct: 1122 PY 1123



 Score =  110 bits (276), Expect = 1e-23
 Identities = 107/434 (24%), Positives = 164/434 (37%), Gaps = 35/434 (8%)

Query: 331 TFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTLGRWVCTE 390
           TF  F P G+   +  N   C     C C +  A+              RC +   +   
Sbjct: 12  TFFFFSPSGSCPYECLNGAFCSKTGTCDCQIFQAL------------GTRCQIIPNMGNG 59

Query: 391 RPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHSETS 450
           R   G C   G     TFD   Y F G C+YI  +     E    + V++      S  S
Sbjct: 60  R--DGICKTWGQYHFETFDGIYYYFPGNCSYIFAKDCGDLEPRYTVWVHNSPKCLGSVYS 117

Query: 451 LVAVV--YLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELV 508
               +  + S Q++I I   E +  NG +  LP     I +  + + ++ + T+FG  L 
Sbjct: 118 CYRSISLFFSNQEEIRIYGHE-IKKNGISLTLPQTIGQIFI-EKLADYILVKTTFGFSLA 175

Query: 509 VQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA---- 564
                I   Y+ +    +G++ GLCGN+N   +DDF           ++F +SW      
Sbjct: 176 WD--GISGIYLKLSEDHKGKSCGLCGNYNDIQSDDFIILQEDYTEDIAMFANSWSVQTPD 233

Query: 565 -GNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQAC 623
              C        +PCS            C +LL+    F  CH  ++P  +   CV   C
Sbjct: 234 DTKCVLTPSDFPNPCSSGMPAFEAIFFKCQILLQ--FPFLSCHEYIDPYLYIASCVNDLC 291

Query: 624 NYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLS 683
             ++   + C A  +Y  ACS  G  +  WR     CT  C  +         C  TC  
Sbjct: 292 KTDDDETY-CRAATEYARACSHAGYPIQDWRDDFPACTDKCDDSFVHRDCISCCPPTCTF 350

Query: 684 LSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGIT 743
                    H    +DGC CPDG  ++  G C+    CPC   G  + +   S +    T
Sbjct: 351 EKQCLGSNLHC---LDGCYCPDGLVMD-NGTCISLENCPCGFHGLAYSVG--SKIEQECT 404

Query: 744 -CHCINGRLSCPQR 756
            C C+ G  +C ++
Sbjct: 405 ECVCVGGVWNCTEQ 418



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 83/353 (23%), Positives = 148/353 (41%), Gaps = 38/353 (10%)

Query: 388  CTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSGVSHS 447
            C E  CP  CS+     + TFD      +   +YIL++ P       ++A  +K  ++ +
Sbjct: 1432 CPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIP----GEIIVAHIEKCSMNQA 1487

Query: 448  ETSLVAVVYLSRQD------KIVISQ-DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMA 500
             +  ++ +   + +      KI++++    V  +     LP+ ++ +++    S ++ + 
Sbjct: 1488 PSGRISGLCFKKLNVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSIEDSGSMYV-IT 1546

Query: 501  TSFGLELV-VQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIA---EGTAS 556
            T  GL +    L  I   +          T GLCG  N D  DD     G          
Sbjct: 1547 TPAGLIIKWSHLTGIIDIHFGFRFNLSSYTEGLCGICNEDPDDDLRMQNGTIITNMEDIG 1606

Query: 557  LFVDSWRAGNCPAALERETDPCSMSQLNKVCAETHCSML--LRTGTVFERCHATVNPAPF 614
            LF++SW        +E+  +  +M +  + C E  CS    L    +F  CH  V+P  F
Sbjct: 1607 LFIESWE-------IEKSFE-VTMRRPVRNCTEHDCSQCIDLLNRRIFIPCHDKVSPEDF 1658

Query: 615  YKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNS 674
               C     NY   + + C AL  YV  C+   + +  WR+  D C++ C     +    
Sbjct: 1659 ---CEKMWINYTYFWNYECDALSAYVALCNKFDICI-QWRTP-DYCSLSCPEGKEYQPCV 1713

Query: 675  QACE-RTCLSLSDRATECHHSAVPV-DGCNCPDGTYLNQ--KGECVRKAQCPC 723
            + CE RTCL   ++    H S + + + C C  GT L++    +C+ + +C C
Sbjct: 1714 RPCEARTCL---NQWFYGHTSCLNLREDCVCKVGTILHRPHSAQCIPEKECAC 1763



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 95/425 (22%), Positives = 160/425 (37%), Gaps = 95/425 (22%)

Query: 794  TGVACVPTKCEPGCVCAEGLYENADGQ-------CVPPEECP-CEFSGVSYPGGAELHTD 845
            TG+ C P K +P   C++ +  N + Q       C    E P C F G      +++   
Sbjct: 1374 TGLECEPQKFDPVYDCSQYICLNMEWQLYNWSLNCPKDVEMPDCGFRGRPVQVNSDI--- 1430

Query: 846  CRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILAT--------- 896
                        C     CP  C++  E  +ITFDG          YIL           
Sbjct: 1431 ------------CCPEWECPCRCSMLSELSIITFDGNNAALYSMASYILVRIPGEIIVAH 1478

Query: 897  -DVCGVNDSQP------TFKILTENVICGNSGVTCSR-AIKIFLGGLSVVLADRNYTVTG 948
             + C +N +         FK L  NV      +  +R A K+ +  + V L   +  ++ 
Sbjct: 1479 IEKCSMNQAPSGRISGLCFKKL--NVTTPIHKIIVNRLARKVEVDSIVVPLPFSSQELSI 1536

Query: 949  EEPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGN 1008
            E+      +T  A  L++  S     +LT I + H      ++  ++    GLCG  N +
Sbjct: 1537 EDSGSMYVITTPA-GLIIKWS-----HLTGIIDIHFGFRFNLSSYTE----GLCGICNED 1586

Query: 1009 MKDDFETRSRYVASSELEL---VNSWKESPLCGDVSFVTDPCSLNAFRRSWAERKCS--- 1062
              DD   ++  + ++  ++   + SW+      + SF     ++    R+  E  CS   
Sbjct: 1587 PDDDLRMQNGTIITNMEDIGLFIESWEI-----EKSFEV---TMRRPVRNCTEHDCSQCI 1638

Query: 1063 -VINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCVDW 1121
             ++N + F  CH KV    +   C +         + EC  DA++AY   C    +C+ W
Sbjct: 1639 DLLNRRIFIPCHDKVSPEDF---CEKMWINYTYFWNYEC--DALSAYVALCNKFDICIQW 1693

Query: 1122 RTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEG---CY 1178
            RTP +C + C        +G               YQPC+ P + ++       G   C 
Sbjct: 1694 RTPDYCSLSC-------PEGK-------------EYQPCVRPCEARTCLNQWFYGHTSCL 1733

Query: 1179 NCSQD 1183
            N  +D
Sbjct: 1734 NLRED 1738



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 50/269 (18%), Positives = 107/269 (39%), Gaps = 16/269 (5%)

Query: 40   PDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGSI---SR 96
            P    C+ +G  H+ +FD   YD+   C      +  D+  +   Q ++  D  I     
Sbjct: 848  PCPAVCTIYGDRHYYSFDGLEYDYISDCQVFLIKSADDSDISVIAQNKKCFDNDIVCSKS 907

Query: 97   IIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP 156
            +++ +G + + +++     K  G     +  N      +     +V    E ++ ++W  
Sbjct: 908  VLISVGDTEIYLNDTPYKQKQSGF----FLENKSTYQLWKAGYYIVVYFPEKDITILWDR 963

Query: 157  DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFA----ALQKLDDPGEI 212
             + + + V  ++  ++ GLCGNFD   +N+  +     +   +      AL + + P E 
Sbjct: 964  KTTIHIKVGPQWKNKLSGLCGNFDKCTSNDMTTSNNLEVRNARVFGDSWALGQCESPDE- 1022

Query: 213  CTFQDIPSTHVRQAQHARICTQLLTLVAPECS--VSKEPFVLSCQADVAAAPQPGPQNSS 270
             T +   +   +     + C+ L + +   C   +    F  +C  D       G     
Sbjct: 1023 -TIKPCEAHQNKFPYAKKECSILYSDIFASCRNVIDVTSFAKNCHEDTCNCNLGGDCECL 1081

Query: 271  CATLSEYSRQCSMVGQPVRRWRSPGLCSV 299
            C +++ Y+ +C   G  +  WRS  +CS+
Sbjct: 1082 CTSIAAYAYKCCQEGISI-HWRSSTVCSL 1109



 Score = 38.5 bits (88), Expect = 0.082
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 15/98 (15%)

Query: 2347 GVCSVREQQEEITFK----------GCMAN--VTVTRCEGACISAASFNIITQQVDARCS 2394
            G C + +++E I  K           CM+   + V  C+G C SA  +NI  +     C 
Sbjct: 2153 GCCKICKREERICQKVIIKSVIRKQDCMSQSPINVASCDGKCPSATIYNINIESHLRFCK 2212

Query: 2395 CCRPLHSYEQQLELPCPDPSTPGRRLVLTLQVFSHCVC 2432
            CCR        + L C   S  G  ++ TLQ    C C
Sbjct: 2213 CCRENGVRNLSVPLYC---SGNGTEIMYTLQEPIDCTC 2247



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 31/102 (30%), Positives = 42/102 (41%), Gaps = 23/102 (22%)

Query: 1153 CTWHYQPCLCP-----SQPQSVPGS---NIEGCY-NCSQDEYFDHEEGVCV---PCMP-- 1198
            C W Y+PC  P     S P+++       +EGC   C ++   D     CV    C+P  
Sbjct: 1277 CEWRYEPCATPCFKTCSDPEALACKFLPPVEGCLPYCPKNMILDEVTLKCVYPRDCIPVI 1336

Query: 1199 PTTP--QPPTTPQLPTTGSRPTQVWPMTGTS--TTIGLLSST 1236
            PT P   PP  P +P        VW M   S  T   +L+ T
Sbjct: 1337 PTEPTLMPPAKPTVPM-----FTVWEMITPSDITVFDMLTPT 1373


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score =  325 bits (833), Expect = 3e-88
 Identities = 192/578 (33%), Positives = 275/578 (47%), Gaps = 52/578 (8%)

Query: 263  QPGPQNSSCATLSEYSRQCSMVGQPV-RRWRSPG--LCSVGQCPANQVYQECGSACVKTC 319
            Q   + S+C T SE SR C+  G      WRS    +C   +CP   +Y+ECG +   TC
Sbjct: 698  QTRDKTSTCDTYSELSRLCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATC 757

Query: 320  SNPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQT- 378
            SN      S C  GC CPEG +L+D+     CV   +CPC   G +Y PGEV    C + 
Sbjct: 758  SNVAPFQDSECVSGCTCPEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQ 817

Query: 379  CRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAV 438
            C C   +W CTE  CPG C +EG S +TTFD   Y F G C ++ + +    ED ++   
Sbjct: 818  CTCQDAKWSCTEALCPGRCKVEGSS-LTTFDGVKYNFPGNCHFLAVHN----EDWSISVE 872

Query: 439  YDKSGVSHSETSLVAVVYLSRQ----DKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTS 494
                    + T L +V  L       DK V + D  VTN+       Y +  I +F  +S
Sbjct: 873  LRPCPSGQTGTCLNSVTLLLNSSVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASS 932

Query: 495  THLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGT 554
            ++LQ+ T F ++L +Q+ P+ Q YV++ P     T GLCG++N    DDF +S  I E T
Sbjct: 933  SYLQVETYFHVKLQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKT 992

Query: 555  ASLFVDSWRAGNCPAALERETDPCSMSQLNK-VCAETHCSMLLRTGTVFERCHATVNPAP 613
            +  F +SW   +CP     + +P S   + K   AE HC +LL +      CH  VNP P
Sbjct: 993  SQAFANSWEMMSCP-----KGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKP 1047

Query: 614  FYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYN 673
            +++ C    C  E +   +C  LG+YV AC+ +   + GWR+ +  C   C     F YN
Sbjct: 1048 YHEECKKYTCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGL--CEHSCPSGLVFKYN 1105

Query: 674  SQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC-----ILEGY 728
             +AC  +C SLS+R   C    VPVDGC CPD  Y N +G CV K+QC C     +++  
Sbjct: 1106 VKACNSSCRSLSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPG 1165

Query: 729  KFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQ-SSENKFGAACAP 787
            K I  + +       C C +G L C     + L +C     +  CS   ++ +    C+ 
Sbjct: 1166 KLIHTDDN------KCVCRDGILLCQIPIDLTLQNCSGGAEYVDCSDPKAQRRTNRTCST 1219

Query: 788  ---------------TCQMLATGVACVPTKCEPGCVCA 810
                           T ++L   V C    CE G  C+
Sbjct: 1220 RNIPVFDDYCGHENGTFRILTESVPC----CEDGLTCS 1253



 Score =  221 bits (564), Expect = 5e-57
 Identities = 193/679 (28%), Positives = 268/679 (39%), Gaps = 91/679 (13%)

Query: 984  MTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDVSFV 1043
            +T   +I  A Q  +CGLCGN NG++KDDF TR   VAS  LE  NSWK S  C D    
Sbjct: 1250 LTCSRKIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWKTSQECSDTVAQ 1309

Query: 1044 TDPCSLNAFRRSWAERKCSVINSQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCD 1103
            T PC  N + ++WA RKC ++   TF  CH+KV    Y++ C+ +AC CD  G     C 
Sbjct: 1310 TFPCDSNPYCKAWAVRKCEILRDSTFRDCHNKVDPSAYHDVCIEEACACDMEGKYLGFCT 1369

Query: 1104 AVAAYAQACLDKGVCVDWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPC--- 1160
            AVA YA+AC   GVCV WR P  CP+YC +YN                 C WHY+PC   
Sbjct: 1370 AVAMYAEACSAVGVCVSWRKPNLCPVYCDYYNA-------------PGECRWHYEPCGTV 1416

Query: 1161 ---LCPSQPQSVPGSN-IEGCYNCSQDE--YFDHEEGVCVPCMPPTTPQPPTTP------ 1208
                C  Q      S+ +EGCY    D   Y D     CV     +       P      
Sbjct: 1417 TAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDVIPAGGVIE 1476

Query: 1209 ------------QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256
                        QL  + + PT       T+T   +LS+     +       P+    +P
Sbjct: 1477 DNCGRTCYCIAGQLECSETAPTNSTFAVSTTTATTILST---GAAITLVTGGPSTAASIP 1533

Query: 1257 ATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRST----ATKPTVTQATTRA-TAS 1311
            A  TSS  T  +   P      T    + +P  +T  +        PTVT A+  A T  
Sbjct: 1534 AITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTG 1593

Query: 1312 TASPATTSTAQSTTRTTMTLP-------------TPATSGTSPTLPKSTNQELPGTTATQ 1358
                ATT  A   T      P             TP  +G   T+  ST       TA+ 
Sbjct: 1594 GVDAATTGAASENTSERAGTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGSITASP 1653

Query: 1359 TTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPS 1418
                  + +S +G T P  G  T  T++E     T++E  +  T  +  S   + S + +
Sbjct: 1654 GASATSSESSKSGTTGPSVGGKTGATSSEA----TSSEGMSGVTGQSLGSTAGSDSEITA 1709

Query: 1419 TGPVTATSFHATTTYPTPSHP----------ETTLPTHVPPFSTSLVTPSTHTVITPTHA 1468
                T +S     T P+P  P               T     +TS    ST   +  T +
Sbjct: 1710 KTSFTGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTS 1769

Query: 1469 -----QMATSASNHSAPTGTIPPPTTLKATGSTHTAP----PITPTTSGTSQAHSSFSTN 1519
                    TS +  + P  T    T + + G+T  AP    P       TS   S  S +
Sbjct: 1770 AGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGH 1829

Query: 1520 KTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPP 1579
             + T L+        P V+  STT+   +P S  T    A   + + S+P  P T     
Sbjct: 1830 DSLTVLNP-AFLRRTPTVSAASTTS---SPVSKHTDAASATAVTISGSKPGTPGTPGGAT 1885

Query: 1580 TG---SSPFSSTGPMTATS 1595
            +G   +S +SS+G  T +S
Sbjct: 1886 SGGKITSGWSSSGTSTGSS 1904



 Score =  125 bits (315), Expect = 4e-28
 Identities = 183/747 (24%), Positives = 294/747 (39%), Gaps = 120/747 (16%)

Query: 43   GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPDGS----ISRII 98
            G+C   G+   +TFD   Y+F G C+++ A   +D   + SV+LR  P G     ++ + 
Sbjct: 834  GRCKVEGSS-LTTFDGVKYNFPGNCHFL-AVHNEDW--SISVELRPCPSGQTGTCLNSVT 889

Query: 99   VELGASV-----VTVSEAIIS---VKDIGVISLPYTSNGLQITPFGQSVRLVAKQLELEL 150
            + L +SV     V  S+  ++   +++ G     Y S+ +QI     S   V     ++L
Sbjct: 890  LLLNSSVPVDKYVFNSDGTVTNDKIRNQGY----YYSDKIQIFNASSSYLQVETYFHVKL 945

Query: 151  EVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG 210
            ++   P   L V +         GLCG+++ K  ++F+S +   LE    A     +   
Sbjct: 946  QIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQN-ILEKTSQAFANSWE--- 1001

Query: 211  EICTFQDIPSTHV---RQAQHARICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQ 263
             +   +  PS+ +   ++    R C  LL    P  S    V+ +P+   C+        
Sbjct: 1002 MMSCPKGNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTCEN 1061

Query: 264  PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSNPQ 323
               Q+  C  L  Y + C+     +  WR+ GLC    CP+  V++    AC  +C +  
Sbjct: 1062 S--QDCLCTILGNYVKACAEKETYIVGWRT-GLCE-HSCPSGLVFKYNVKACNSSCRSLS 1117

Query: 324  HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAACQTCRCTL 383
                                D S +   VPV  C C    AMY   E        C C +
Sbjct: 1118 E------------------RDRSCDVEDVPVDGCTCP--DAMYQNNEGNCVLKSQCDCYI 1157

Query: 384  GRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDGALMAVYDKSG 443
               V           ++ G  + T D +     G    ILL   Q+P D   + + + SG
Sbjct: 1158 NDEV-----------MQPGKLIHTDDNKCVCRDG----ILLC--QIPID---LTLQNCSG 1197

Query: 444  VSHSETSLVAVVYLSRQDKIVISQDEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSF 503
             +          Y+   D     + +  TN          TRNI VF     H       
Sbjct: 1198 GAE---------YVDCSDP----KAQRRTNR------TCSTRNIPVFDDYCGHENGTFRI 1238

Query: 504  GLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWR 563
              E V            +   F+G+  GLCGN NGD  DDFTT        A  F +SW+
Sbjct: 1239 LTESVPCCEDGLTCSRKIIVAFQGKVCGLCGNNNGDLKDDFTTRYSSVASGALEFGNSWK 1298

Query: 564  AGNCPAALERETDPCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQ-- 621
                 +    +T PC  +   K  A   C +L    + F  CH  V+P+ ++  C+ +  
Sbjct: 1299 TSQECSDTVAQTFPCDSNPYCKAWAVRKCEIL--RDSTFRDCHNKVDPSAYHDVCIEEAC 1356

Query: 622  ACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIPC-----TGNTTFSYN--S 674
            AC+ E  +   C A+  Y  ACS  GV +  WR   + C + C      G   + Y    
Sbjct: 1357 ACDMEGKYLGFCTAVAMYAEACSAVGVCV-SWRKP-NLCPVYCDYYNAPGECRWHYEPCG 1414

Query: 675  QACERTCLSLSDRATECHHSAVPVDGC--NCPDGT-YLNQKG-ECVRKAQCPCILEGYKF 730
                +TC    D+      S++ ++GC   CPD   YL++   +CV  ++C C    Y  
Sbjct: 1415 TVTAKTC---KDQLVGQKFSSL-LEGCYAKCPDSAPYLDENTMKCVSLSECSCF---YND 1467

Query: 731  ILAEQSTVIN--GITCHCINGRLSCPQ 755
            ++     + +  G TC+CI G+L C +
Sbjct: 1468 VIPAGGVIEDNCGRTCYCIAGQLECSE 1494



 Score =  124 bits (311), Expect = 1e-27
 Identities = 119/466 (25%), Positives = 189/466 (40%), Gaps = 56/466 (12%)

Query: 761  LASCQAPKTFKSCSQSS----------ENKFGAACAPTCQMLATGVACVP-TKCEPGCVC 809
            L +   P TF+S    S          E      C P+     + VA    ++C  GC C
Sbjct: 715  LCASDGPGTFESWRSDSDVVCETQRCPEQHIYKECGPSNPATCSNVAPFQDSECVSGCTC 774

Query: 810  AEGLYEN---ADGQCVPPEECPCEFSGVSYPGGAELHTDCRT-CSCSRGRWACQQGTHCP 865
             EG   +     G+CV   ECPCE SG  Y  G      C + C+C   +W+C +   CP
Sbjct: 775  PEGYLLDDIGEKGKCVLKAECPCESSGTVYQPGEVREGPCGSQCTCQDAKWSCTEAL-CP 833

Query: 866  STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCS 925
              C + G   + TFDG ++ F GNC ++       V++   +  +       G +G TC 
Sbjct: 834  GRCKVEGSS-LTTFDGVKYNFPGNCHFL------AVHNEDWSISVELRPCPSGQTG-TCL 885

Query: 926  RAIKIFLGGLSVVLADRNYTVTGEEPHVQLGVTPGALSLVVDISIPGRYNLTLIWNRHMT 985
             ++ + L   SV +    +   G   + ++       S  + I       L +    H+ 
Sbjct: 886  NSVTLLLNS-SVPVDKYVFNSDGTVTNDKIRNQGYYYSDKIQIFNASSSYLQVETYFHVK 944

Query: 986  ILIRIARASQ----------DPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKESP 1035
            + I+I    Q              GLCG++N   +DDF +    +  +     NSW E  
Sbjct: 945  LQIQIVPVMQLYVSMPPNQFTDTVGLCGSYNNKAEDDFMSSQNILEKTSQAFANSW-EMM 1003

Query: 1036 LCGDVSFVTDPCS-LNAFRRSWAERKCSVI--NSQTFATCHSKVYHLPYYEACVRDACGC 1092
             C       +P S ++  +  +AER C ++  +S   A+CH  V   PY+E C +  C C
Sbjct: 1004 SCPK----GNPSSCISIEKEKFAERHCGILLDSSGPLASCHPIVNPKPYHEECKKYTCTC 1059

Query: 1093 DSGGDCECLCDAVAAYAQACLDKGV-CVDWRT---PAFCPIYCGF-YNTHTQDGHGEYQY 1147
            ++  D  CLC  +  Y +AC +K    V WRT      CP    F YN    +       
Sbjct: 1060 ENSQD--CLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRSLS 1117

Query: 1148 TQEANCTWHYQP---CLCPSQPQSVPGSNIEGCYNCSQDEYFDHEE 1190
             ++ +C     P   C C   P ++  +N   C   SQ + + ++E
Sbjct: 1118 ERDRSCDVEDVPVDGCTC---PDAMYQNNEGNCVLKSQCDCYINDE 1160



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 62/223 (27%), Positives = 88/223 (39%), Gaps = 29/223 (13%)

Query: 743  TCHCINGRLSCPQRPQMFLASCQAPKTF----------KSCSQSSENKFGA-ACAPTCQM 791
            TC C N +         ++ +C   +T+           SC      K+   AC  +C+ 
Sbjct: 1056 TCTCENSQDCLCTILGNYVKACAEKETYIVGWRTGLCEHSCPSGLVFKYNVKACNSSCRS 1115

Query: 792  LATGVACVPTKCEP--GCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTC 849
            L+        +  P  GC C + +Y+N +G CV   +C C  +      G  +HTD   C
Sbjct: 1116 LSERDRSCDVEDVPVDGCTCPDAMYQNNEGNCVLKSQCDCYINDEVMQPGKLIHTDDNKC 1175

Query: 850  SCSRGRWACQQGTHCPSTCTLY----GEGHVITFD--GQRFVFDGNC---EYILATDVCG 900
             C  G   CQ     P   TL     G  +V   D   QR   +  C      +  D CG
Sbjct: 1176 VCRDGILLCQ----IPIDLTLQNCSGGAEYVDCSDPKAQRRT-NRTCSTRNIPVFDDYCG 1230

Query: 901  VNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRN 943
              +   TF+ILTE+V C   G+TCSR I +   G    L   N
Sbjct: 1231 HENG--TFRILTESVPCCEDGLTCSRKIIVAFQGKVCGLCGNN 1271



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 120/457 (26%), Positives = 177/457 (38%), Gaps = 53/457 (11%)

Query: 1751 SHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS 1810
            S T+ T+     ST+T +      STG    +     +T++ +P   T+ S  TGTT   
Sbjct: 1493 SETAPTNSTFAVSTTTATTI---LSTGAAITLVTGGPSTAASIPAITTSSSETTGTT--- 1546

Query: 1811 STGPVTATSFQTTTTYPTPSHPHTT--LPTHVPSFSTSLVTPSTHTVIIPTHT----QMA 1864
              GP+T               P TT    T VP  STS     T  V+ PT T       
Sbjct: 1547 -LGPLT--------------EPFTTGITETSVPIISTSGNAGMT-GVVSPTVTGASGMAG 1590

Query: 1865 TSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSS 1924
            T+  + +  TG     T+ +A   T      TP   G S    +   A  S S      S
Sbjct: 1591 TTGGVDAATTGAASENTSERA--GTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGS 1648

Query: 1925 -THHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGP 1983
             T  P  + TS+     + + +GT  P     + ++S   T     S  TG S  S+ G 
Sbjct: 1649 ITASPGASATSS-----ESSKSGTTGPSVGGKTGATSSEATSSEGMSGVTGQSLGSTAGS 1703

Query: 1984 MTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPT 2043
             +  + +T+ T  +P   + T P+   P   S  T     V  T      TS ++ ST  
Sbjct: 1704 DSEITAKTSFTGSSPP-GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGST-E 1761

Query: 2044 GTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPP 2103
            G+V   T   + GS +TA      TSGT  T    +TA + +  +S  +      SS P 
Sbjct: 1762 GSVEATT---SAGSGNTA-----GTSGTGDTGPG-NTAVSGTPVVSPGATPGAPGSSTPG 1812

Query: 2104 SSPI--TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT 2161
             + I  T+      S    ++  N      +P+ SA ST SS  P S  +   S+ +V  
Sbjct: 1813 EADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSS--PVSKHTDAASATAVTI 1870

Query: 2162 SSSFVSAPVHSTTLSSGSH--SSLSTHPTTASVSASP 2196
            S S    P      +SG    S  S+  T+   S +P
Sbjct: 1871 SGSKPGTPGTPGGATSGGKITSGWSSSGTSTGSSNTP 1907



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 117/479 (24%), Positives = 181/479 (37%), Gaps = 113/479 (23%)

Query: 1844 STSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTS 1903
            S +  T ST  V   T T + ++ +  ++ TG   P T       T ++   T TT G  
Sbjct: 1493 SETAPTNSTFAVSTTTATTILSTGAAITLVTGG--PSTAASIPAITTSSSETTGTTLGPL 1550

Query: 1904 QSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPV-AHTTSASSS-- 1960
              P  F+T  T TS+P   S++ +  +T   +  +T      GT   V A TT A+S   
Sbjct: 1551 TEP--FTTGITETSVPI-ISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENT 1607

Query: 1961 --RLPTPFTTHSPPT---GSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTS 2015
              R  TP  + + P    GS+P    GP    S  T                     S  
Sbjct: 1608 SERAGTPRVSGATPAVGGGSTP-GEAGPGATVSGSTGV-------------------SAG 1647

Query: 2016 LVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTS--- 2072
             +T S            A++ S  S+ +GT  P    K TG+T +    +   SG +   
Sbjct: 1648 SITASPG----------ASATSSESSKSGTTGPSVGGK-TGATSSEATSSEGMSGVTGQS 1696

Query: 2073 --QTHSSFSTATASSSFISSSSWLPQNSSSRP-PSSPITTQLPHLSSATTPVSTTNQLSS 2129
               T  S S  TA +SF  SS   P    +RP P SP      H S  TT          
Sbjct: 1697 LGSTAGSDSEITAKTSFTGSS---PPGKLTRPSPGSP-----GHFSGGTTEWGN------ 1742

Query: 2130 SFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLS----T 2185
                           V ++ ++ + +S ++G++   V A   +T+  SG+ +  S    T
Sbjct: 1743 ---------------VATTGAAGENTSGALGSTEGSVEA---TTSAGSGNTAGTSGTGDT 1784

Query: 2186 HPTTASVSASPLF-----PSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSH 2240
             P   +VS +P+      P +P +ST   A + +T                +   +  S 
Sbjct: 1785 GPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNT----------------SFGKSGKSG 1828

Query: 2241 LASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSP 2299
              S T+  P+  R T      P  S+ STTS   S  T   ++  V+++    G P +P
Sbjct: 1829 HDSLTVLNPAFLRRT------PTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTP 1881



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 105/435 (24%), Positives = 157/435 (36%), Gaps = 58/435 (13%)

Query: 1649 PTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS 1708
            PT +    +T  AT    T   +TL T G S A S        T+  S T+ T     T 
Sbjct: 1497 PTNSTFAVSTTTATTILSTGAAITLVTGGPSTAAS----IPAITTSSSETTGTTLGPLTE 1552

Query: 1709 TSTTNITP------------------NPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLH 1750
              TT IT                   +PT TG   M  TT G   + +  ++  TS    
Sbjct: 1553 PFTTGITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAG 1612

Query: 1751 SHTSSTHHPEVTSTSTT-SITPNHTSTG---------TRTPVAHTTSATSSRLPTPFTTH 1800
            +   S   P V   ST     P  T +G         T +P A  TS+ SS+  T   + 
Sbjct: 1613 TPRVSGATPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGPSV 1672

Query: 1801 SPPTGTTPISSTGP-----VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTV 1855
               TG T   +T       VT  S  +T    +     T+     P    +  +P +   
Sbjct: 1673 GGKTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGS--- 1729

Query: 1856 IIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
              P H    T+   +   TG     T+  A GST  +   T T++G+  +  +  T  T 
Sbjct: 1730 --PGHFSGGTTEWGNVATTGAAGENTS-GALGSTEGSVEAT-TSAGSGNTAGTSGTGDTG 1785

Query: 1916 TSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGS 1975
               P +T+ +  P V+P +T       +ST     + +T+   S +     + H   T  
Sbjct: 1786 ---PGNTAVSGTPVVSPGATPG--APGSSTPGEADIGNTSFGKSGK-----SGHDSLTVL 1835

Query: 1976 SP-FSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMAT 2034
            +P F    P    S  +TT+ P   H      T V    +   TP T     T+  ++ +
Sbjct: 1836 NPAFLRRTP--TVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGG-ATSGGKITS 1892

Query: 2035 SASIHSTPTGTVPPP 2049
              S   T TG+   P
Sbjct: 1893 GWSSSGTSTGSSNTP 1907



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 89/376 (23%), Positives = 138/376 (36%), Gaps = 54/376 (14%)

Query: 2010 PPFSTSLVTPSTHTVIITTHTQM-------ATSASIHSTPTG-------TVPPPTTLKAT 2055
            P  ST  V+ +T T I++T   +       +T+ASI +  T        T+ P T    T
Sbjct: 1497 PTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTT 1556

Query: 2056 GSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLP--------QNSSSRPPSSPI 2107
            G T T+ P+  T+     T     T T +S    ++  +         +N+S R  +  +
Sbjct: 1557 GITETSVPIISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAGTPRV 1616

Query: 2108 TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVS 2167
            +   P +   +TP       + S S   SA S  +S   S+ SS  + S + G S     
Sbjct: 1617 SGATPAVGGGSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGPSVGG-- 1674

Query: 2168 APVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLP 2227
                     +G+ SS +T     S        S+  + + I A    T SSP       P
Sbjct: 1675 --------KTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSP-------P 1719

Query: 2228 ISTVTVSPTPSSHLASSTIAFPSTPRT-TASTHTAPAFSS-----QSTTSRSTSLTTRVP 2281
                  SP    H +  T  + +   T  A  +T+ A  S     ++TTS  +  T    
Sbjct: 1720 GKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNT--AG 1777

Query: 2282 TSGFVSLTSGVTGIPTSPVTN-------LTTRHPGPTLSPTTRFLTSSLTAHGSTPASAP 2334
            TSG      G T +  +PV +         +  PG      T F  S  + H S     P
Sbjct: 1778 TSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNP 1837

Query: 2335 VSSLGTPTPTSPGVCS 2350
                 TPT ++    S
Sbjct: 1838 AFLRRTPTVSAASTTS 1853



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 113/421 (26%), Positives = 166/421 (39%), Gaps = 62/421 (14%)

Query: 1617 PPFSTSLVTPSTHTVITPTHAQM-------ATSASI------HSMPTGTIPPPTTLK-AT 1662
            P  ST  V+ +T T I  T A +       +T+ASI       S  TGT   P T    T
Sbjct: 1497 PTNSTFAVSTTTATTILSTGAAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTT 1556

Query: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITP---NPT 1719
            G T T+  + ++TSG +     ++   T  S  + T+    A  T  ++ N +     P 
Sbjct: 1557 GITETSVPI-ISTSGNAGMTGVVSPTVTGASGMAGTTGGVDAATTGAASENTSERAGTPR 1615

Query: 1720 STGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT--STG 1777
             +G  P  V    T       +T   ST + S  S T  P  ++TS+ S     T  S G
Sbjct: 1616 VSGATP-AVGGGSTPGEAGPGATVSGSTGV-SAGSITASPGASATSSESSKSGTTGPSVG 1673

Query: 1778 TRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTT-----TYPTPSHP 1832
             +T  A ++ ATSS   +  T  S   G+T  S +     TSF  ++     T P+P  P
Sbjct: 1674 GKTG-ATSSEATSSEGMSGVTGQS--LGSTAGSDSEITAKTSFTGSSPPGKLTRPSPGSP 1730

Query: 1833 ----------HTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTT 1882
                           T     +TS    ST   +  T T   +  +  +  TG   P  T
Sbjct: 1731 GHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEAT-TSAGSGNTAGTSGTGDTGPGNT 1789

Query: 1883 IKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS---TSLPYHTSST--------HHPEVT 1931
               +G+   +P  TP   G+S +P       TS   +    H S T          P V+
Sbjct: 1790 -AVSGTPVVSPGATPGAPGSS-TPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVS 1847

Query: 1932 PTSTTNI-TPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTG---SSPFSSTGPMTAT 1987
              STT+    KHT   + T V    + S S+  TP T     +G   +S +SS+G  T +
Sbjct: 1848 AASTTSSPVSKHTDAASATAV----TISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGS 1903

Query: 1988 S 1988
            S
Sbjct: 1904 S 1904



 Score = 41.2 bits (95), Expect = 0.013
 Identities = 50/211 (23%), Positives = 78/211 (36%), Gaps = 23/211 (10%)

Query: 661  TIPCTGNTTFSYNSQACERTCLSLSDRA-TECHHSAVPVDGCNCPDGTYLNQKGECVRKA 719
            T PC  N    Y      R C  L D    +CH+   P          Y +    C+ +A
Sbjct: 1310 TFPCDSNP---YCKAWAVRKCEILRDSTFRDCHNKVDP--------SAYHDV---CIEEA 1355

Query: 720  QCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSEN 779
             C C +EG K++    +  +    C  +   +S  ++P +    C        C    E 
Sbjct: 1356 -CACDMEG-KYLGFCTAVAMYAEACSAVGVCVSW-RKPNLCPVYCDYYNAPGECRWHYE- 1411

Query: 780  KFGAACAPTC--QMLATGVACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYP 837
              G   A TC  Q++    + +   C   C  +    +    +CV   EC C ++ V  P
Sbjct: 1412 PCGTVTAKTCKDQLVGQKFSSLLEGCYAKCPDSAPYLDENTMKCVSLSECSCFYNDV-IP 1470

Query: 838  GGAELHTDC-RTCSCSRGRWACQQGTHCPST 867
             G  +  +C RTC C  G+  C +     ST
Sbjct: 1471 AGGVIEDNCGRTCYCIAGQLECSETAPTNST 1501



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 14/49 (28%), Positives = 28/49 (57%)

Query: 43  GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPTFSVQLRRGPD 91
           G+ STW  G + +F+  ++ F  +C Y F   C ++   F+++++R  D
Sbjct: 595 GEISTWSKGAYKSFNGRIFFFESSCPYTFCRHCIESGGDFNIEIKRNND 643


>gi|239751787 PREDICTED: hypothetical protein XP_002348012 [Homo
            sapiens]
          Length = 3003

 Score =  311 bits (798), Expect = 4e-84
 Identities = 328/1244 (26%), Positives = 474/1244 (38%), Gaps = 185/1244 (14%)

Query: 40   PDK-GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD--AFPTFSVQLRRGPDGSIS- 95
            PD+ G C   G  H+ +FD   +DF GTC Y+   +C    A P F V +     GS + 
Sbjct: 858  PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 917

Query: 96   ----RIIVELGASVVTVSEAI---ISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLEL 148
                 + VE     V V       + V D+ +  LP+ +   Q+  F Q    V +  + 
Sbjct: 918  SYTRAVRVEARGVKVAVRREYPGQVLVDDV-LQYLPFQAADGQVQVFRQGRDAVVRT-DF 975

Query: 149  ELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFA-ALQKL 206
             L V +  ++ +   V   Y   +CGLCGNF+G   ++     G +      F  + Q+ 
Sbjct: 976  GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE 1035

Query: 207  DDPG----EICTFQDIPSTHVRQAQHARICTQLLTLVAP--ECSVSKEP--FVLSCQADV 258
              PG    E      + S   +Q Q    C  L     P  EC    +P   V  C  D 
Sbjct: 1036 TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDR 1095

Query: 259  AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
               P  G     C  L+ Y+  C   G  V  WRS  LC +  CP +  Y+ C   C  +
Sbjct: 1096 CLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPLS 1152

Query: 319  CSN--PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAA- 375
            C +      C S C  GC C EG  L+      +C+P+  C CV  G  + PG+      
Sbjct: 1153 CGDLPVPGGCGSECHEGCVCDEGFALS----GESCLPLASCGCVHQGTYHPPGQTFYPGP 1208

Query: 376  -CQT-CRCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARPY 413
             C + C C  G  V C    C  H                   C   G    TTFD R +
Sbjct: 1209 GCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRF 1268

Query: 414  RFHGTCTYILLQSPQLPEDGALMAVYDKS---GVSHSETSLVAVVYLSRQDKIVISQDEV 470
             F GTC Y+L Q+          AV  ++   G      + V  V ++     +  +   
Sbjct: 1269 DFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 1328

Query: 471  VTNNGEAKWLPYKTRNITV-FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQT 529
            VT NG    LP    N  +   Q  + + + T FGL +   L  ++   VTV   +  Q 
Sbjct: 1329 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQQM 1386

Query: 530  RGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWR----------AGNCPAALER--ETDP 577
             GLCGN+NGD  DDF    G   G A+ F +SW              CP   E    +  
Sbjct: 1387 CGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHK 1446

Query: 578  CSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALG 637
            C      K   E  C +L         CH  V+P    K C++  C        +C+ + 
Sbjct: 1447 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 1506

Query: 638  DYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP 697
             YV AC   G  +  WR+    C + C  N+ +   +  C   C +LS    +C      
Sbjct: 1507 AYVSACQAAGGHVEPWRTET-FCPMECPPNSHYELCADTCSLGCSALS-APPQCQDGC-- 1562

Query: 698  VDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRP 757
             +GC C  G   N +  CV   QC C   G  +   EQ+ +I+     C           
Sbjct: 1563 AEGCQCDSGFLYNGQA-CVPIQQCGCYHNGV-YYEPEQTVLIDNCRQQC----------- 1609

Query: 758  QMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENA 817
                 +C A K                          G+ C    C+PG VC        
Sbjct: 1610 -----TCHAGK--------------------------GMVCQEHSCKPGQVCQP---SGG 1635

Query: 818  DGQCVPPEECPCEFSGVSYPGGAELHTDCR---TCSCSRGRWACQQGTHCPSTCTLYGEG 874
               CV  + C     GV+          CR   TC    G+  C    +  +TC L+G+ 
Sbjct: 1636 ILSCVTKDPC----HGVT----------CRPQETCKEQGGQGVCL--PNYEATCWLWGDP 1679

Query: 875  HVITFDGQRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIFL 932
            H  +FDG++F F G C Y+LAT  C GV+    T F + T+N   GN  V+  R + +  
Sbjct: 1680 HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAA 1739

Query: 933  GGLSV-----VLADRNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRHM 984
             G ++      +      V G    + + V  G +S+    S   +   + L + ++ + 
Sbjct: 1740 LGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNW 1799

Query: 985  TILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGDVS 1041
             + + +  +    +CGLCGN + N  +D    +  +A S      SW+     PLC D  
Sbjct: 1800 RVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDEC 1859

Query: 1042 FVTDP-CSLNAFRRSWAERKCSVINSQT---FATCHSKVYHLPYYEACVRDACGCDSGGD 1097
              + P C  +   +      C  + S T   F TCH+ V    +++ CV D   C  GGD
Sbjct: 1860 RGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGD 1917

Query: 1098 CECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWH 1156
             + LC A+A+Y  AC   GV + DWR    C I C       ++ H E        C   
Sbjct: 1918 RDILCKALASYVAACQAAGVVIEDWRAQVGCEITC------PENSHYE---VCGPPC--- 1965

Query: 1157 YQPCLCPS-----QPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP 1195
              P  CPS      P    G  +EGC  C  D  F      CVP
Sbjct: 1966 --PASCPSPAPLTTPAVCEGPCVEGC-QC--DAGFVLSADRCVP 2004



 Score =  279 bits (714), Expect = 2e-74
 Identities = 311/1237 (25%), Positives = 445/1237 (35%), Gaps = 225/1237 (18%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPT-----FSV----QLRRGPDGSIS 95
            C  WG  H+ +FD   +DF GTCNY+ A T      T     F+V    Q R  P  S  
Sbjct: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732

Query: 96   RIIV--ELGASVVTVSEAIISVKDI--GVIS-LPYT-SNGLQITPFGQSVRLVAKQLELE 149
            R++    LG ++    + I  V+    GV++ LP + ++G      G S  L+     L+
Sbjct: 1733 RVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGASKALLVADFGLQ 1792

Query: 150  LEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDP 209
            +   W  +  + V +   Y G +CGLCGN D    N+ V   G  L P           P
Sbjct: 1793 VSYDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAP 1849

Query: 210  G--EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQA 256
            G   +C      +    P   + Q +    C  L +            V  E F   C  
Sbjct: 1850 GWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLASGTGGPFTTCHAHVPPESFFKGCVL 1909

Query: 257  DVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACV 316
            DV      G ++  C  L+ Y   C   G  +  WR+   C +  CP N  Y+ CG  C 
Sbjct: 1910 DVCMGG--GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGPPCP 1966

Query: 317  KTCSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGE 370
             +C +P        C   C  GC C  G VL+       CVP+   C C  +G  +  G 
Sbjct: 1967 ASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGS 2022

Query: 371  VTIA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFV 405
               A     Q CRC  G    VCT   C                       C   G    
Sbjct: 2023 EFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHY 2082

Query: 406  TTFDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDK 462
             T D   + F GTC Y+L      P L  +   + V ++   S + +   +V        
Sbjct: 2083 VTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHS 2142

Query: 463  IVISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVT 520
            + +S      +  +G    LP++  ++     +   + + T+ GL L        +  V 
Sbjct: 2143 LTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVP 2202

Query: 521  VGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----D 576
                +     GLCGN+N D  DD     G   G        W+ G      E  +     
Sbjct: 2203 AA--YAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPS 2252

Query: 577  PCSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAAL 636
            PC+  Q         C ++  T      CH  V PA +++ C+  AC  +     +C A+
Sbjct: 2253 PCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAV 2312

Query: 637  GDYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAV 696
              YV AC   G  L  WR   D C + C  ++ +     +C  +C SLS  A E   SA 
Sbjct: 2313 ATYVAACQAAGAQLGEWRRP-DFCPLQCPAHSHYELCGDSCPVSCPSLS--APEGCESAC 2369

Query: 697  PVDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQR 756
              +GC C D  ++     CV   QC C+ +G  + L                G +  P  
Sbjct: 2370 R-EGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPL----------------GEVFYP-- 2409

Query: 757  PQMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPG--CVCAEGLY 814
                                     G  C   C+            C PG    C EG  
Sbjct: 2410 -------------------------GPECERRCE------------CGPGGHVTCQEG-- 2430

Query: 815  ENADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEG 874
                  C P EEC  E  GV           C    C R              C   G  
Sbjct: 2431 ----AACGPHEECRLE-DGVQ---------ACHATGCGR--------------CLANGGI 2462

Query: 875  HVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGG 934
            H IT DG+ +   G+C Y+LA  VC        F I+ E     N+     R +    G 
Sbjct: 2463 HYITLDGRVYDLHGSCSYVLA-QVCHPKPGDEDFSIVLEK----NAAGDLQRLLVTVAGQ 2517

Query: 935  LSVVLADRNYTVTGEEPHVQLGVTPGALSLVVD---ISIPGRYNLTLIWNRHMTILIRIA 991
            +  +   +  TV GE   V L V  G + +  +   + +     L L+++    +L+ I 
Sbjct: 2518 VVSLAQGQQVTVDGEA--VALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIP 2575

Query: 992  RASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK---ESPLCGDVSFV--TDP 1046
               +  LCGLCGNFNGN  DDF   +   ASS      +W+    S  CG+         
Sbjct: 2576 SPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPV 2635

Query: 1047 CSLNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDA 1104
            C         +   C  + +    FATC + +    Y+  CV D C     GD   LC +
Sbjct: 2636 CLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRS 2693

Query: 1105 VAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP 1163
            +AAY  AC   GV V  WRT +FCP++C  ++                    HY  C   
Sbjct: 2694 LAAYTAACQAAGVAVKPWRTDSFCPLHCPAHS--------------------HYSICTRT 2733

Query: 1164 SQPQSVPGSNIEGC-----YNCSQDEYFDHEEGVCVP 1195
             Q      S + GC       C  D+ F   +GVC+P
Sbjct: 2734 CQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 2770



 Score =  272 bits (695), Expect = 3e-72
 Identities = 319/1268 (25%), Positives = 465/1268 (36%), Gaps = 248/1268 (19%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQLRRGPDG----SISRII 98
            C   G  H++TFD   +DF GTC Y+ A TC  +     F+V       G    S++R+I
Sbjct: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311

Query: 99   -VELGASVVTVSEAIISVKDIGV-ISLPYT-SNG-LQITPFGQSVRLVAKQLELELEVVW 154
             V++    + + +    V   GV + LP   +NG ++ +  G  V +   + +  L V +
Sbjct: 1312 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVI---ETDFGLRVAY 1368

Query: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
                ++ V V   Y  QMCGLCGN++G   ++F    G      ++F    +   P   C
Sbjct: 1369 DLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 1428

Query: 214  T--------FQDIPSTHV------RQAQHARICTQLLTLVAPECSVSK----EPFVLSCQ 255
                      +D   +H       ++ Q    C  L +   P  S  K    +  +  C 
Sbjct: 1429 LPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 1488

Query: 256  ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC 315
             D+      G  +  C+ +  Y   C   G  V  WR+   C + +CP N  Y+ C   C
Sbjct: 1489 FDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM-ECPPNSHYELCADTC 1545

Query: 316  VKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGE-VT 372
               CS  +    C   C  GC C  G     L N   CVP+ QC C  +G  Y P + V 
Sbjct: 1546 SLGCSALSAPPQCQDGCAEGCQCDSGF----LYNGQACVPIQQCGCYHNGVYYEPEQTVL 1601

Query: 373  IAAC-QTCRCTLGR-WVCTERPC-PGH---------------------------CSLEGG 402
            I  C Q C C  G+  VC E  C PG                            C  +GG
Sbjct: 1602 IDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGG 1661

Query: 403  SFVT-----------------TFDARPYRFHGTCTYILLQS--PQLPEDGA--LMAVYDK 441
              V                  +FD R + F GTC Y+L  +  P +   G          
Sbjct: 1662 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 1721

Query: 442  SGVSHSETSLVAVVYLSRQD-KIVISQDEV----VTNNGEAKWLPYKTRN--ITVFRQTS 494
                +   S V VV ++     I I +DE+    V  NG    LP    +  I+V +  S
Sbjct: 1722 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVCVNGVLTALPVSVADGRISVAQGAS 1781

Query: 495  THLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGT 554
              L +A  FGL++       ++  VT+   + G   GLCGN + +  +D     G    +
Sbjct: 1782 KALLVA-DFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS 1838

Query: 555  ASLFVDSWRA------------GNCPAALERETDPCSMSQLNKVCAETHCSMLLR-TGTV 601
              ++  SWRA            G+CP         C   +L +      C  L   TG  
Sbjct: 1839 IPIWGGSWRAPGWDPLCWDECRGSCPT--------CPEDRLEQYEGPGFCGPLASGTGGP 1890

Query: 602  FERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCT 661
            F  CHA V P  F+K CV   C        +C AL  YV AC   GV++  WR+ V  C 
Sbjct: 1891 FTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCE 1949

Query: 662  IPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQC 721
            I C  N+ +      C  +C S +   T        V+GC C  G  L+           
Sbjct: 1950 ITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS----------- 1998

Query: 722  PCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKF 781
                       A++   +N       NG              C A  T+      SE   
Sbjct: 1999 -----------ADRCVPLN-------NG------------CGCWANGTYHEA--GSEFWA 2026

Query: 782  GAACAPTCQMLATG--VACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGG 839
               C+  C+    G  + C P  C  G VC  GL  +    C P     C+         
Sbjct: 2027 DGTCSQWCRCGPGGGSLVCTPASCGLGEVC--GLLPSGQHGCQPVSTAECQ--------- 2075

Query: 840  AELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVC 899
                                           +G+ H +T DG RF F G CEY+L+    
Sbjct: 2076 ------------------------------AWGDPHYVTLDGHRFDFQGTCEYLLSAPCH 2105

Query: 900  GVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLA---DRNYTVTGEEPHV--Q 954
            G       F +   N   G+  V+ +R++ + +   S+ L+    R   V G    +  Q
Sbjct: 2106 GPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQ 2165

Query: 955  LGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFE 1014
            L     A     D+ +     L+L ++    + +R+  A    LCGLCGN+N +  DD +
Sbjct: 2166 LDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLK 2225

Query: 1015 TRSRYVASSELELVNSWKESPLCGDV--SFVTDPCSLNAFRRSWAERKCSVINSQ--TFA 1070
                  A  ++           CG+        PC+            C VI++     A
Sbjct: 2226 AVGGKPAGWQVGGAQG------CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLA 2279

Query: 1071 TCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPI 1129
             CH  V    Y++ C+ DAC     G    LC AVA Y  AC   G  + +WR P FCP+
Sbjct: 2280 PCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL 2337

Query: 1130 YCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP--SQPQSVPGSNIEGCYNCSQDEYFD 1187
             C          H  Y+   + +C     P  CP  S P+    +  EGC  C  D  F 
Sbjct: 2338 QC--------PAHSHYELCGD-SC-----PVSCPSLSAPEGCESACREGCV-C--DAGFV 2380

Query: 1188 HEEGVCVP 1195
                 CVP
Sbjct: 2381 LSGDTCVP 2388



 Score =  263 bits (672), Expect = 2e-69
 Identities = 258/1054 (24%), Positives = 404/1054 (38%), Gaps = 195/1054 (18%)

Query: 44   QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
            +C  WG  H+ T D H +DF GTC Y+ +A C         F+V +     GS +     
Sbjct: 2073 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2132

Query: 96   RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
             + +++    +T+S        + GV ++LP+  + L       +  +V     L L   
Sbjct: 2133 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSL--A 2190

Query: 154  WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
            +  DS + + V   Y   +CGLCGN++    ++  +  GK        A       GE C
Sbjct: 2191 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 2245

Query: 214  TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
              +  PS    + Q +      C  +     P       V    +   C  D  A    G
Sbjct: 2246 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 2303

Query: 266  PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
                 C  ++ Y   C   G  +  WR P  C + QCPA+  Y+ CG +C  +C +    
Sbjct: 2304 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAP 2362

Query: 324  HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---------- 373
              C S+C  GC C  G VL+      TCVPV QC C+  G  Y  GEV            
Sbjct: 2363 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 2418

Query: 374  ------------AAC---QTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGT 418
                        AAC   + CR   G   C    C G C   GG    T D R Y  HG+
Sbjct: 2419 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 2477

Query: 419  CTYILLQ--SPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
            C+Y+L Q   P+ P D     V +K+     +  LV V        + ++Q + VT +GE
Sbjct: 2478 CSYVLAQVCHPK-PGDEDFSIVLEKNAAGDLQRLLVTVA----GQVVSLAQGQQVTVDGE 2532

Query: 477  AKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNF 536
            A  LP     + V  +   ++ + T+ GL L+          +++   FRG+  GLCGNF
Sbjct: 2533 AVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDA--HLLMSIPSPFRGRLCGLCGNF 2589

Query: 537  NGDTTDDFTTSMGIAEGTASLFVDSWRAGN-------------CPAALERETDPCSMSQL 583
            NG+ +DDF    G A  +   F  +WRA               CP  L  ET P   ++ 
Sbjct: 2590 NGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEA 2649

Query: 584  NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
                    C  L      F  C A ++P+ ++++CVY  C  +     +C +L  Y  AC
Sbjct: 2650 --------CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAAC 2701

Query: 644  SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
               GV +  WR+    C + C  ++ +S  ++ C+ +C +LS   T C  +    +GC C
Sbjct: 2702 QAAGVAVKPWRTD-SFCPLHCPAHSHYSICTRTCQGSCAALSG-LTGC--TTRCFEGCEC 2757

Query: 704  PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
             D   L+Q G C+    C C   G +++    S + +  +  C                 
Sbjct: 2758 DDRFLLSQ-GVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERC----------------- 2798

Query: 764  CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
                    SCS SS                 G+ C    C PG VC              
Sbjct: 2799 --------SCSSSS-----------------GLTCQAAGCPPGRVC-------------- 2819

Query: 824  PEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQR 883
                             E+  + R C  +RG             C L    ++ TFDG R
Sbjct: 2820 -----------------EVKAEARNCWATRG------------LCVLSVGANLTTFDGAR 2850

Query: 884  FVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRN 943
                    Y L++   G+ ++ P ++++ E  IC        +    F  G+  +  ++ 
Sbjct: 2851 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKG 2910

Query: 944  YTVTG---EEPHVQLGVTPGALSLVVDISIPGRYNLTL-IW-NRHMTILIRIARASQDPL 998
              V G   + P  +L     ++S   D S+  R    + +W   +  + + ++      L
Sbjct: 2911 VWVNGLRVDLPAEKLASV--SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKL 2968

Query: 999  CGLCGNFNGNMKDDFETRSRYVASSELELVNSWK 1032
            CG CGNF+G+  +D+        S E   +  W+
Sbjct: 2969 CGACGNFDGDQTNDWHD------SQEKPAMEKWR 2996



 Score =  250 bits (639), Expect = 1e-65
 Identities = 217/779 (27%), Positives = 330/779 (42%), Gaps = 96/779 (12%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCK--DAFPTFSVQLRRGPDGSISRIIVELG 102
            C   G  H++TFD   YD  GTC+Y     C   D  P FSV+ +    GS  R +  +G
Sbjct: 472  CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS--RRVSYVG 529

Query: 103  ASVVTVSEAIISVK--DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP---- 156
               V      +S+   ++G + +    + L ++     +R+        +E+V+G     
Sbjct: 530  LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY 589

Query: 157  --DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
              D  L + +  ++  Q+CGLCGN++G   ++F++ +G    +  +FA+  KLDD   +C
Sbjct: 590  DWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLC 649

Query: 214  ---TFQDIPSTHVRQAQH---ARICTQLLTLVAP----ECSVSKEPFVLSCQADVAAAPQ 263
                  + P+    QAQH    R+C  L  L  P      ++   PF+  C  D+     
Sbjct: 650  EDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV-- 707

Query: 264  PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN-- 321
             G + S C  LS Y++ C  +G  V  WRSP  C +  CPAN  Y+ CG AC  +C+   
Sbjct: 708  GGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL-SCPANSRYELCGPACPTSCNGAA 766

Query: 322  -PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIA--ACQ- 377
             P +     C  GC C  G V    ++   CVP + C C   G   APG+   A   CQ 
Sbjct: 767  APSNCSGRPCVEGCVCLPGFV----ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 822

Query: 378  --TCRCTLGRWVCTER-PCP-------------------GHCSLEGGSFVTTFDARPYRF 415
              TC     +  C ++  CP                   G C   G     +FD R + F
Sbjct: 823  RCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF 882

Query: 416  HGTCTYILL----QSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQD--E 469
             GTCTY+L+    Q+  LP    L+    +   + S T  V V   +R  K+ + ++   
Sbjct: 883  MGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVE--ARGVKVAVRREYPG 940

Query: 470  VVTNNGEAKWLPYKTRN--ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVT--VGPQF 525
             V  +   ++LP++  +  + VFRQ      + T FGL +       + A VT  V   +
Sbjct: 941  QVLVDDVLQYLPFQAADGQVQVFRQ-GRDAVVRTDFGLTVTYD----WNARVTAKVPSSY 995

Query: 526  RGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNK 585
                 GLCGNFNGD  DD     G     A  F +SW+    P      T+P    +L+ 
Sbjct: 996  AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC--GATEPGDCPKLDS 1053

Query: 586  VCAE-----THCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYV 640
            + A+       C +L      F  CH+ ++P    + CVY  C        +C AL  Y 
Sbjct: 1054 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1113

Query: 641  HACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSL---SDRATECHHSAVP 697
             AC   G  +  WRS  + C + C  ++ +   S  C  +C  L       +ECH     
Sbjct: 1114 AACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECH----- 1167

Query: 698  VDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGI--TCHCINGRL-SC 753
             +GC C +G  L+ +  C+  A C C+ +G      +      G    CHC  G L SC
Sbjct: 1168 -EGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224



 Score =  169 bits (429), Expect = 2e-41
 Identities = 157/578 (27%), Positives = 247/578 (42%), Gaps = 64/578 (11%)

Query: 31   RLKDSPQT--APDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQL 86
            RL+D  Q   A   G+C   G  H+ T D  VYD  G+C+Y+ A  C  K     FS+ L
Sbjct: 2440 RLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL 2499

Query: 87   RRGPDGSISRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQL 146
             +   G + R++V +   VV++++      D   ++LP     +++T  G+++ L   Q 
Sbjct: 2500 EKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL---QT 2556

Query: 147  ELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-HKFAALQK 205
               L +++  D+HL++ +   + G++CGLCGNF+G  +++FV   G        F A  +
Sbjct: 2557 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 2616

Query: 206  LDDP----GEICTFQDIP---STHVRQAQHARICTQLLTLVAP----ECSVSKEPFVLSC 254
                    GE C  Q  P   +      +    C QL     P    +  +S   +   C
Sbjct: 2617 APGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQC 2676

Query: 255  QADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSA 314
              D+ A  Q G +   C +L+ Y+  C   G  V+ WR+   C +  CPA+  Y  C   
Sbjct: 2677 VYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL-HCPAHSHYSICTRT 2733

Query: 315  CVKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT 372
            C  +C+  +    C++ C  GC C +  +L    +   C+PV  C C  H   Y P   +
Sbjct: 2734 CQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDCGCT-HNGRYLPVNSS 2788

Query: 373  I----------------AACQTCRCTLGRWVC----TERPC---PGHCSLEGGSFVTTFD 409
            +                  CQ   C  GR VC      R C    G C L  G+ +TTFD
Sbjct: 2789 LLTSDCSERCSCSSSSGLTCQAAGCPPGR-VCEVKAEARNCWATRGLCVLSVGANLTTFD 2847

Query: 410  ARPYRFHGTCTYIL-LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV-ISQ 467
                       Y L  + P L        V  +  + H +T  V  V++  QD +V ++ 
Sbjct: 2848 GARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTP 2907

Query: 468  DEVVTNNGEAKWLP-YKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFR 526
            ++ V  NG    LP  K  +++V R     L +    G++  V L    +  V V     
Sbjct: 2908 NKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHA 2965

Query: 527  GQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA 564
            G+  G CGNF+GD T+D+  S    E  A   ++ WRA
Sbjct: 2966 GKLCGACGNFDGDQTNDWHDSQ---EKPA---MEKWRA 2997



 Score =  168 bits (426), Expect = 5e-41
 Identities = 146/500 (29%), Positives = 210/500 (42%), Gaps = 82/500 (16%)

Query: 763  SCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCV 822
            SC A   ++ C        G AC  +C   A    C    C  GCVC  G   +  G CV
Sbjct: 744  SCPANSRYELC--------GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG-GACV 794

Query: 823  PPEECPCEFSGVSYPGGAELHTD--C-RTCSCS--------RGRWACQQGTHCP------ 865
            P   C C F G+    G E+  D  C R C+C+        R + +C  G  C       
Sbjct: 795  PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 854

Query: 866  -------STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG 918
                    TC   G+ H ++FDG+RF F G C Y+L    CG N + P F++L EN   G
Sbjct: 855  GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRG 913

Query: 919  NSGVTCSRAIKIFLGGLSVVLADRNYT----VTGEEPHVQLGVTPGALSLVV---DISIP 971
            +  V+ +RA+++   G+ V +  R Y     V     ++      G + +     D  + 
Sbjct: 914  SQTVSYTRAVRVEARGVKVAVR-REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 972

Query: 972  GRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSW 1031
              + LT+ ++ +  +  ++  +  + LCGLCGNFNG+  DD   R    A++ L   NSW
Sbjct: 973  TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW 1032

Query: 1032 KES--PLCGDVSFVTDP--C----SLNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPY 1081
            +E   P CG     T+P  C    SL A ++  ++ +C ++      F  CHSK+     
Sbjct: 1033 QEETRPGCG----ATEPGDCPKLDSLVA-QQLQSKNECGILADPKGPFRECHSKLDPQGA 1087

Query: 1082 YEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQD 1140
               CV D C     G    LCDA+A YA AC   G  V  WR+   CP+ C  ++ +   
Sbjct: 1088 VRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145

Query: 1141 GHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCY-NCSQDEYFDHEEGVCVP---- 1195
             +G         C     P  C   P  VPG     C+  C  DE F      C+P    
Sbjct: 1146 SYG---------C-----PLSCGDLP--VPGGCGSECHEGCVCDEGFALSGESCLPLASC 1189

Query: 1196 -CMPPTTPQPPTTPQLPTTG 1214
             C+   T  PP     P  G
Sbjct: 1190 GCVHQGTYHPPGQTFYPGPG 1209



 Score =  135 bits (340), Expect = 5e-31
 Identities = 119/435 (27%), Positives = 177/435 (40%), Gaps = 45/435 (10%)

Query: 374 AACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDG 433
           AA Q C+   G+  C        C  +G    TTFD R Y   GTC+Y +++     ED 
Sbjct: 450 AAGQRCQVVGGKAGCVAEST-AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL--CSEDD 506

Query: 434 ALMAVYDKSGVSHSETSLVAVVYL----SRQDKIVISQDEV----VTNNGEAKWLPYKTR 485
            L A   ++   H  +  V+ V L    +    + +++ EV    V N      +     
Sbjct: 507 TLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566

Query: 486 NITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFT 545
            + V+ Q+     +   FGL  VV      Q  +++  +F+ Q  GLCGN+NGD  DDF 
Sbjct: 567 RLRVY-QSGPRAVVELVFGL--VVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623

Query: 546 TSMGIAEGTASLFVDSWRAGN----CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTV 601
           T  G     A  F  SW+  +    C    +     C+  Q      +  C ML +    
Sbjct: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683

Query: 602 FERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCT 661
           F  CH T++P PF ++CVY  C        +C  L  Y  AC   G+ +  WRS   NC 
Sbjct: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA-NCP 742

Query: 662 IPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP-VDGCNCPDGTYLNQKGECVRKAQ 720
           + C  N+ +     AC  +C   +  A   + S  P V+GC C  G ++   G CV  + 
Sbjct: 743 LSCPANSRYELCGPACPTSC---NGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASS 798

Query: 721 CPCILEGYKFI---------LAEQSTVING----ITCHCINGRLSCPQ----RPQMFLAS 763
           C C  +G +           L ++    NG    +TC     + SCP       Q  L  
Sbjct: 799 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTC---RDKQSCPAGERCSVQNGLLG 855

Query: 764 CQAPKTFKSCSQSSE 778
           C  P  F +C  S +
Sbjct: 856 CY-PDRFGTCQGSGD 869



 Score =  127 bits (320), Expect = 1e-28
 Identities = 108/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)

Query: 846  CRTCSCSRGRWACQ-----QGTHCPST--CTLYGEGHVITFDGQRFVFDGNCEYILATDV 898
            C    C+ G+  CQ      G    ST  C   G+ H  TFDG+R+   G C Y +  ++
Sbjct: 444  CEGMQCAAGQ-RCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMV-EL 501

Query: 899  CGVNDSQPTFKILTENVICGNSGVTC---------SRAIKIFLGGLSVVLADRNYTVTGE 949
            C  +D+ P F +  +N   G+  V+          S ++ +  G +  VL D       +
Sbjct: 502  CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDN------Q 555

Query: 950  EPHVQLGVTPGALSL-------VVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLC 1002
               + + ++ G L +       VV++     + L + ++    + + +    QD +CGLC
Sbjct: 556  RSRLPVSLSEGRLRVYQSGPRAVVELV----FGLVVTYDWDCQLALSLPARFQDQVCGLC 611

Query: 1003 GNFNGNMKDDFETRSRYVASSELELVNSWKESP---LCGDVSFVTDP-CSLNAFRRSWAE 1058
            GN+NG+  DDF T    +A   +E  +SWK      LC D      P C+    +    +
Sbjct: 612  GNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGD 671

Query: 1059 RKCSVIN--SQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKG 1116
            R C ++      FA CH  +   P+ E CV D C    GG+   LC  ++AYAQACL+ G
Sbjct: 672  RLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV--GGERLSLCRGLSAYAQACLELG 729

Query: 1117 VCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEA---NCTWHYQPCLCPSQPQSVPGS 1172
            + V DWR+PA CP+ C          +  Y+    A   +C     P  C  +P      
Sbjct: 730  ISVGDWRSPANCPLSC--------PANSRYELCGPACPTSCNGAAAPSNCSGRP------ 775

Query: 1173 NIEGCYNCSQDEYFDHEEGVCVP 1195
             +EGC  C     F    G CVP
Sbjct: 776  CVEGCV-CLPG--FVASGGACVP 795


>gi|154146262 Fc fragment of IgG binding protein [Homo sapiens]
          Length = 5405

 Score =  311 bits (796), Expect = 7e-84
 Identities = 327/1242 (26%), Positives = 474/1242 (38%), Gaps = 183/1242 (14%)

Query: 40   PDK-GQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD--AFPTFSVQLRRGPDGSIS- 95
            PD+ G C   G  H+ +FD   +DF GTC Y+   +C    A P F V +     GS + 
Sbjct: 858  PDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTV 917

Query: 96   ----RIIVELGASVVTVSEAI---ISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQLEL 148
                 + VE     V V       + V D+ +  LP+ +   Q+  F Q    V +  + 
Sbjct: 918  SYTRAVRVEARGVKVAVRREYPGQVLVDDV-LQYLPFQAADGQVQVFRQGRDAVVRT-DF 975

Query: 149  ELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-KFLEPHKFA-ALQKL 206
             L V +  ++ +   V   Y   +CGLCGNF+G   ++     G +      F  + Q+ 
Sbjct: 976  GLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEE 1035

Query: 207  DDPG----EICTFQDIPSTHVRQAQHARICTQLLTLVAP--ECSVSKEP--FVLSCQADV 258
              PG    E      + S   +Q Q    C  L     P  EC    +P   V  C  D 
Sbjct: 1036 TRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDR 1095

Query: 259  AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
               P  G     C  L+ Y+  C   G  V  WRS  LC +  CP +  Y+ C   C  +
Sbjct: 1096 CLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLS-CPPHSHYEACSYGCPLS 1152

Query: 319  CSN--PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIAA- 375
            C +      C S C  GC C EG  L+      +C+P+  C CV  G  + PG+      
Sbjct: 1153 CGDLPVPGGCGSECHEGCVCDEGFALS----GESCLPLASCGCVHQGTYHPPGQTFYPGP 1208

Query: 376  -CQT-CRCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARPY 413
             C + C C  G  V C    C  H                   C   G    TTFD R +
Sbjct: 1209 GCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRF 1268

Query: 414  RFHGTCTYILLQSPQLPEDGALMAVYDKS---GVSHSETSLVAVVYLSRQDKIVISQDEV 470
             F GTC Y+L Q+          AV  ++   G      + V  V ++     +  +   
Sbjct: 1269 DFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWK 1328

Query: 471  VTNNGEAKWLPYKTRNITV-FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQT 529
            VT NG    LP    N  +   Q  + + + T FGL +   L  ++   VTV   +  Q 
Sbjct: 1329 VTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQQM 1386

Query: 530  RGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWR----------AGNCPAALER--ETDP 577
             GLCGN+NGD  DDF    G   G A+ F +SW              CP   E    +  
Sbjct: 1387 CGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHK 1446

Query: 578  CSMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALG 637
            C      K   E  C +L         CH  V+P    K C++  C        +C+ + 
Sbjct: 1447 CPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIH 1506

Query: 638  DYVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP 697
             YV AC   G  +  WR+    C + C  N+ +   +  C   C +LS    +C      
Sbjct: 1507 AYVSACQAAGGHVEPWRTET-FCPMECPPNSHYELCADTCSLGCSALS-APPQCQDGC-- 1562

Query: 698  VDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRP 757
             +GC C  G   N +  CV   QC C   G  +   EQ+ +I+     C           
Sbjct: 1563 AEGCQCDSGFLYNGQA-CVPIQQCGCYHNGV-YYEPEQTVLIDNCRQQC----------- 1609

Query: 758  QMFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENA 817
                 +C A K                          G+ C    C+PG VC        
Sbjct: 1610 -----TCHAGK--------------------------GMVCQEHSCKPGQVCQP---SGG 1635

Query: 818  DGQCVPPEECPCEFSGVSYPGGAELHTDCR---TCSCSRGRWACQQGTHCPSTCTLYGEG 874
               CV  + C     GV+          CR   TC    G+  C    +  +TC L+G+ 
Sbjct: 1636 ILSCVTKDPC----HGVT----------CRPQETCKEQGGQGVCL--PNYEATCWLWGDP 1679

Query: 875  HVITFDGQRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIFL 932
            H  +FDG++F F G C Y+LAT  C GV+    T F + T+N   GN  V+  R + +  
Sbjct: 1680 HYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAA 1739

Query: 933  GGLSVVLAD---RNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRHMTI 986
             G ++ +         V G    + + V  G +S+    S   +   + L + ++ +  +
Sbjct: 1740 LGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRV 1799

Query: 987  LIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGDVSFV 1043
             + +  +    +CGLCGN + N  +D    +  +A S      SW+     PLC D    
Sbjct: 1800 DVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRG 1859

Query: 1044 TDP-CSLNAFRRSWAERKCSVINSQT---FATCHSKVYHLPYYEACVRDACGCDSGGDCE 1099
            + P C  +   +      C  +   T   F TCH+ V    +++ CV D   C  GGD +
Sbjct: 1860 SCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRD 1917

Query: 1100 CLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQ 1158
             LC A+A+Y  AC   GV + DWR    C I C       ++ H E      + C     
Sbjct: 1918 ILCKALASYVAACQAAGVVIEDWRAQVGCEITC------PENSHYE---VCGSPC----- 1963

Query: 1159 PCLCPS-----QPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP 1195
            P  CPS      P    G  +EGC  C  D  F      CVP
Sbjct: 1964 PASCPSPAPLTTPAVCEGPCVEGC-QC--DAGFVLSADRCVP 2002



 Score =  305 bits (781), Expect = 4e-82
 Identities = 324/1236 (26%), Positives = 472/1236 (38%), Gaps = 187/1236 (15%)

Query: 44   QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
            +C  WG  H+ T D H +DF GTC Y+ +A C         F+V +     GS +     
Sbjct: 3272 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 3331

Query: 96   RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
             + +++    +T+S        + GV ++LP+  + L       +  +V     L L   
Sbjct: 3332 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSL--A 3389

Query: 154  WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
            +  DS + + V   Y G +CGLCGN++    ++  +  GK        A       GE C
Sbjct: 3390 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 3444

Query: 214  TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
              +  PS    + Q +      C  +     P       V    +   C  D  A    G
Sbjct: 3445 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 3502

Query: 266  PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
                 C  ++ Y   C   G  +R WR P  C   QCPA+  Y+ CG +C  +C +    
Sbjct: 3503 HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPF-QCPAHSHYELCGDSCPGSCPSLSAP 3561

Query: 324  HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---AACQT-C 379
              C S+C  GC C  G VL+      TCVPV QC C LH   Y P   T      C + C
Sbjct: 3562 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLC 3616

Query: 380  RCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARPYRFHGTC 419
            RC  G  V C    C  H                   C   G    TTFD   + F GTC
Sbjct: 3617 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTC 3676

Query: 420  TYILLQSPQLPEDGALMAVYDKS---GVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
             Y+L Q+          AV  ++   G      + V  V ++     +  +   VT NG 
Sbjct: 3677 VYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGV 3736

Query: 477  AKWLPYKTRNITV-FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535
               LP    N  +   Q  + + + T FGL +   L  ++   VTV   +     GLCGN
Sbjct: 3737 DMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQLMCGLCGN 3794

Query: 536  FNGDTTDDFTTSMGIAEGTASLFVDSWR----------AGNCP--AALERETDPCSMSQL 583
            +NGD  DDF    G   G A+ F +SW              CP  +A    +D C     
Sbjct: 3795 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELE 3854

Query: 584  NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
             K   E  C +L         CH  V+P    K C++  C        +C+ +  YV AC
Sbjct: 3855 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 3914

Query: 644  SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
               G  +  WR+    C + C  N+ +   +  C   C +LS    +C       +GC C
Sbjct: 3915 QAAGGHVEPWRNET-FCPMECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEGCQC 3970

Query: 704  PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
              G   N +  CV   QC C   G  +   EQ+ +I+     C                +
Sbjct: 3971 DSGFLYNGQA-CVPIQQCGCYHNGV-YYEPEQTVLIDNCRQQC----------------T 4012

Query: 764  CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
            C   K                           V C    C+PG VC           CV 
Sbjct: 4013 CHVGKV--------------------------VVCQEHSCKPGQVCQP---SGGILSCVT 4043

Query: 824  PEECPCEFSGVSYPGGAELHTDCR---TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFD 880
             + C     GV+          CR   TC    G+  C    +  +TC L+G+ H  +FD
Sbjct: 4044 KDPC----HGVT----------CRPQETCKEQGGQGVCL--PNYEATCWLWGDPHYHSFD 4087

Query: 881  GQRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIFLGGLSVV 938
            G++F F G C Y+LAT  C GV+    T F + T+N   GN  V+  R + +   G ++ 
Sbjct: 4088 GRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 4147

Query: 939  LAD---RNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRHMTILIRIAR 992
            +         V G    + + V  G +S+    S   +   + L + ++ +  + + +  
Sbjct: 4148 IHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPS 4207

Query: 993  ASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGDVSFVTDP-CS 1048
            +    +CGLCGN + N  +D    +  +A S      SW+     PLC D    + P C 
Sbjct: 4208 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 4267

Query: 1049 LNAFRRSWAERKCSVINSQT---FATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAV 1105
             +   +      C  ++S T   F TCH+ V    +++ CV D   C  GGD + LC A+
Sbjct: 4268 EDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKAL 4325

Query: 1106 AAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPS 1164
            A+Y  AC   GV + DWR    C I C       ++ H E        C     P  CPS
Sbjct: 4326 ASYVAACQAAGVVIEDWRAQVGCEITC------PENSHYE---VCGPPC-----PASCPS 4371

Query: 1165 -----QPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP 1195
                  P    G  +EGC  C  D  F      CVP
Sbjct: 4372 PAPLTTPAVCEGPCVEGC-QC--DAGFVLSADRCVP 4404



 Score =  303 bits (775), Expect = 2e-81
 Identities = 322/1236 (26%), Positives = 470/1236 (38%), Gaps = 187/1236 (15%)

Query: 44   QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
            +C  WG  H+ T D H ++F GTC Y+ +A C         F+V +     GS +     
Sbjct: 2071 ECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 2130

Query: 96   RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
             + +++    +T+S        + GV ++LP+  + L       +  +V     L L   
Sbjct: 2131 SVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSL--A 2188

Query: 154  WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
            +  DS + + V   Y G +CGLCGN++    ++  +  GK        A       GE C
Sbjct: 2189 FDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 2243

Query: 214  TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
              +  PS    + Q +      C  +     P       V    +   C  D  A    G
Sbjct: 2244 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 2301

Query: 266  PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
                 C  ++ Y   C   G  +R WR P  C   QCPA+  Y+ CG +C  +C +    
Sbjct: 2302 HPGGLCPAVATYVAACQAAGAQLREWRRPDFCPF-QCPAHSHYELCGDSCPGSCPSLSAP 2360

Query: 324  HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---AACQT-C 379
              C S+C  GC C  G VL+      TCVPV QC C LH   Y P   T      C + C
Sbjct: 2361 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGC-LHDDRYYPLGQTFYPGPGCDSLC 2415

Query: 380  RCTLGRWV-CTERPCPGH-------------------CSLEGGSFVTTFDARPYRFHGTC 419
            RC  G  V C    C  H                   C   G    TTFD R + F GTC
Sbjct: 2416 RCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTC 2475

Query: 420  TYILLQSPQLPEDGALMAVYDKS---GVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
             Y+L Q+          AV  ++   G      + V  V ++     +  +   VT NG 
Sbjct: 2476 VYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGV 2535

Query: 477  AKWLPYKTRNITV-FRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGN 535
               LP    N  +   Q  + + + T FGL +   L  ++   VTV   +     GLCGN
Sbjct: 2536 DMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDL--VYYVRVTVPGNYYQLMCGLCGN 2593

Query: 536  FNGDTTDDFTTSMGIAEGTASLFVDSWR----------AGNCPAALER--ETDPCSMSQL 583
            +NGD  DDF    G   G A+ F +SW              CP   E    ++ C     
Sbjct: 2594 YNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELE 2653

Query: 584  NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
             K   E  C +L         CH  V+P    K C++  C        +C+ +  YV AC
Sbjct: 2654 KKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSAC 2713

Query: 644  SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
               G  +  WR+    C + C  N+ +   +  C   C +LS    +C       +GC C
Sbjct: 2714 QAAGGQVEPWRNET-FCPMECPQNSHYELCADTCSLGCSALS-APLQCPDGC--AEGCQC 2769

Query: 704  PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
              G   N +  CV   QC C   G  +   EQ+ +I+     C                +
Sbjct: 2770 DSGFLYNGQA-CVPIQQCGCYHNG-AYYEPEQTVLIDNCRQQC----------------T 2811

Query: 764  CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
            C   K                           V C    C+PG VC           CV 
Sbjct: 2812 CHVGKV--------------------------VVCQEHSCKPGQVCQP---SGGILSCVN 2842

Query: 824  PEECPCEFSGVSYPGGAELHTDCR---TCSCSRGRWACQQGTHCPSTCTLYGEGHVITFD 880
             + C     GV+          CR   TC    G+  C    +  +TC L+G+ H  +FD
Sbjct: 2843 KDPC----HGVT----------CRPQETCKEQGGQGVCL--PNYEATCWLWGDPHYHSFD 2886

Query: 881  GQRFVFDGNCEYILATDVC-GVNDSQPT-FKILTENVICGNSGVTCSRAIKIFLGGLSVV 938
            G++F F G C Y+LAT  C GV+    T F + T+N   GN  V+  R + +   G ++ 
Sbjct: 2887 GRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNIS 2946

Query: 939  LAD---RNYTVTGEEPHVQLGVTPGALSLVVDIS---IPGRYNLTLIWNRHMTILIRIAR 992
            +         V G    + + V  G +S+    S   +   + L + ++ +  + + +  
Sbjct: 2947 IHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPS 3006

Query: 993  ASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---SPLCGDVSFVTDP-CS 1048
            +    +CGLCGN + N  +D    +  +A S      SW+     PLC D    + P C 
Sbjct: 3007 SYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCP 3066

Query: 1049 LNAFRRSWAERKCSVINSQT---FATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAV 1105
             +   +      C  +   T   F TCH+ V    +++ CV D   C  GGD + LC A+
Sbjct: 3067 EDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV--CMGGGDRDILCKAL 3124

Query: 1106 AAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPS 1164
            A+Y  AC   GV + DWR    C I C       ++ H E        C     P  CPS
Sbjct: 3125 ASYVAACQAAGVVIEDWRAQVGCEITC------PENSHYE---VCGPPC-----PASCPS 3170

Query: 1165 -----QPQSVPGSNIEGCYNCSQDEYFDHEEGVCVP 1195
                  P    G  +EGC  C  D  F      CVP
Sbjct: 3171 PAPLTTPAVCEGPCVEGC-QC--DAGFVLSADRCVP 3203



 Score =  291 bits (744), Expect = 7e-78
 Identities = 310/1240 (25%), Positives = 451/1240 (36%), Gaps = 219/1240 (17%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPT-----FSV----QLRRGPDGSIS 95
            C  WG  H+ +FD   +DF GTCNY+ A T      T     F+V    Q R  P  S  
Sbjct: 1673 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 1732

Query: 96   RIIV--ELGASVVTVSEAIISVKDIGVIS-LPYT-SNGLQITPFGQSVRLVAKQLELELE 151
            R++    LG ++    + I  V+  GV++ LP + ++G      G S  L+     L++ 
Sbjct: 1733 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 1792

Query: 152  VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG- 210
              W  +  + V +   Y G +CGLCGN D    N+ V   G  L P           PG 
Sbjct: 1793 YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAPGW 1849

Query: 211  -EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQADV 258
              +C      +    P   + Q +    C  L              V  E F   C  DV
Sbjct: 1850 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 1909

Query: 259  AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
                  G ++  C  L+ Y   C   G  +  WR+   C +  CP N  Y+ CGS C  +
Sbjct: 1910 CMGG--GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGSPCPAS 1966

Query: 319  CSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGEVT 372
            C +P        C   C  GC C  G VL+       CVP+   C C  +G  +  G   
Sbjct: 1967 CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGSEF 2022

Query: 373  IA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFVTT 407
             A     Q CRC  G    VCT   C                       C   G     T
Sbjct: 2023 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 2082

Query: 408  FDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV 464
             D   + F GTC Y+L      P L  +   + V ++   S + +   +V        + 
Sbjct: 2083 LDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 2142

Query: 465  ISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVG 522
            +S      +  +G    LP++  ++     +   + + T+ GL L        +  V   
Sbjct: 2143 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 2202

Query: 523  PQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----DPC 578
              + G   GLCGN+N D  DD     G   G        W+ G      E  +     PC
Sbjct: 2203 --YAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPC 2252

Query: 579  SMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGD 638
            +  Q         C ++  T      CH  V PA +++ C+  AC  +     +C A+  
Sbjct: 2253 TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 2312

Query: 639  YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPV 698
            YV AC   G  L  WR   D C   C  ++ +     +C  +C SLS  A E   SA   
Sbjct: 2313 YVAACQAAGAQLREWRRP-DFCPFQCPAHSHYELCGDSCPGSCPSLS--APEGCESACR- 2368

Query: 699  DGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQ 758
            +GC C D  ++     CV   QC C+ +   + L +                        
Sbjct: 2369 EGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQ------------------------ 2403

Query: 759  MFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATG-VACVPTKCEPGCVCAEGLYENA 817
                      TF           G  C   C+    G V+C P+ C P   C        
Sbjct: 2404 ----------TFYP---------GPGCDSLCRCREGGEVSCEPSSCGPHETCR------- 2437

Query: 818  DGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVI 877
                               P G  L         + G   CQ            G+ H  
Sbjct: 2438 -------------------PSGGSLG------CVAVGSTTCQAS----------GDPHYT 2462

Query: 878  TFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSV 937
            TFDG+RF F G C Y+LA   CG       F +L ENV  GN  V+ +R I + +   ++
Sbjct: 2463 TFDGRRFDFMGTCVYVLA-QTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 2521

Query: 938  VLADRNYTVTGEEPHVQLGVTPG-----ALSLVVDISIPGRYNLTLIWNRHMTILIRIAR 992
             L  R + VT     ++L V        A     D+ I   + L + ++    + + +  
Sbjct: 2522 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 2581

Query: 993  ASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---------SPLC---GDV 1040
                 +CGLCGN+NG+ KDDF+  +   A +  E  NSW+E          P C    + 
Sbjct: 2582 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEG 2641

Query: 1041 SFVTDPCSLNAFRRSWAERKCSVINSQT--FATCHSKVYHLPYYEACVRDACGCDSGGDC 1098
               ++ C     ++   E  C +++S T   ++CH  V      + C+ D   C  GG+ 
Sbjct: 2642 CIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNL 2699

Query: 1099 ECLCDAVAAYAQACLDKGVCVD-WRTPAFCPIYCGFYNTHTQDGHGEY-QYTQEANCTWH 1156
              LC  + AY  AC   G  V+ WR   FCP+ C       Q+ H E    T    C+  
Sbjct: 2700 SILCSNIHAYVSACQAAGGQVEPWRNETFCPMEC------PQNSHYELCADTCSLGCSAL 2753

Query: 1157 YQPCLCPSQPQSVPGSNIEGC-YNCSQDEYFDHEEGVCVP 1195
              P  CP           +GC   C  D  F +    CVP
Sbjct: 2754 SAPLQCP-----------DGCAEGCQCDSGFLYNGQACVP 2782



 Score =  289 bits (740), Expect = 2e-77
 Identities = 311/1240 (25%), Positives = 449/1240 (36%), Gaps = 219/1240 (17%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPT-----FSV----QLRRGPDGSIS 95
            C  WG  H+ +FD   +DF GTCNY+ A T      T     F+V    Q R  P  S  
Sbjct: 2874 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 2933

Query: 96   RIIV--ELGASVVTVSEAIISVKDIGVIS-LPYT-SNGLQITPFGQSVRLVAKQLELELE 151
            R++    LG ++    + I  V+  GV++ LP + ++G      G S  L+     L++ 
Sbjct: 2934 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVS 2993

Query: 152  VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG- 210
              W  +  + V +   Y G +CGLCGN D    N+ V   G  L P           PG 
Sbjct: 2994 YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAPGW 3050

Query: 211  -EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQADV 258
              +C      +    P   + Q +    C  L              V  E F   C  DV
Sbjct: 3051 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 3110

Query: 259  AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
                  G ++  C  L+ Y   C   G  +  WR+   C +  CP N  Y+ CG  C  +
Sbjct: 3111 CMGG--GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGPPCPAS 3167

Query: 319  CSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGEVT 372
            C +P        C   C  GC C  G VL+       CVP+   C C  +G  +  G   
Sbjct: 3168 CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGSEF 3223

Query: 373  IA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFVTT 407
             A     Q CRC  G    VCT   C                       C   G     T
Sbjct: 3224 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 3283

Query: 408  FDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV 464
             D   + F GTC Y+L      P L  +   + V ++   S + +   +V        + 
Sbjct: 3284 LDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 3343

Query: 465  ISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVG 522
            +S      +  +G    LP++  ++     +   + + T+ GL L        +  V   
Sbjct: 3344 LSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 3403

Query: 523  PQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----DPC 578
              + G   GLCGN+N D  DD     G   G        W+ G      E  +     PC
Sbjct: 3404 --YAGSLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPC 3453

Query: 579  SMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGD 638
            +  Q         C ++  T      CH  V PA +++ C+  AC  +     +C A+  
Sbjct: 3454 TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 3513

Query: 639  YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPV 698
            YV AC   G  L  WR   D C   C  ++ +     +C  +C SLS  A E   SA   
Sbjct: 3514 YVAACQAAGAQLREWRRP-DFCPFQCPAHSHYELCGDSCPGSCPSLS--APEGCESACR- 3569

Query: 699  DGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQ 758
            +GC C D  ++     CV   QC C+ +   + L +                        
Sbjct: 3570 EGCVC-DAGFVLSGDTCVPVGQCGCLHDDRYYPLGQ------------------------ 3604

Query: 759  MFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATG-VACVPTKCEPGCVCAEGLYENA 817
                      TF           G  C   C+    G V+C P+ C P   C        
Sbjct: 3605 ----------TFYP---------GPGCDSLCRCREGGEVSCEPSSCGPHETCR------- 3638

Query: 818  DGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVI 877
                               P G  L         + G   CQ            G+ H  
Sbjct: 3639 -------------------PSGGSLG------CVAVGSTTCQAS----------GDPHYT 3663

Query: 878  TFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSV 937
            TFDG RF F G C Y+LA   CG       F +L ENV  GN  V+ +R I + +   ++
Sbjct: 3664 TFDGHRFDFMGTCVYVLA-QTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTL 3722

Query: 938  VLADRNYTVTGEEPHVQLGVTPG-----ALSLVVDISIPGRYNLTLIWNRHMTILIRIAR 992
             L  R + VT     ++L V        A     D+ I   + L + ++    + + +  
Sbjct: 3723 RLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPG 3782

Query: 993  ASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWKE---------SPLCGDVS-- 1041
                 +CGLCGN+NG+ KDDF+  +   A +  E  NSW+E          P C   S  
Sbjct: 3783 NYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAG 3842

Query: 1042 -FVTDPCSLNAFRRSWAERKCSVINSQT--FATCHSKVYHLPYYEACVRDACGCDSGGDC 1098
               +D C     ++   E  C +++S T   ++CH  V      + C+ D   C  GG+ 
Sbjct: 3843 CIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDL--CLGGGNL 3900

Query: 1099 ECLCDAVAAYAQACLDKGVCVD-WRTPAFCPIYCGFYNTHTQDGHGEY-QYTQEANCTWH 1156
              LC  + AY  AC   G  V+ WR   FCP+ C       Q+ H E    T    C+  
Sbjct: 3901 SILCSNIHAYVSACQAAGGHVEPWRNETFCPMEC------PQNSHYELCADTCSLGCSAL 3954

Query: 1157 YQPCLCPSQPQSVPGSNIEGC-YNCSQDEYFDHEEGVCVP 1195
              P  CP           +GC   C  D  F +    CVP
Sbjct: 3955 SAPLQCP-----------DGCAEGCQCDSGFLYNGQACVP 3983



 Score =  283 bits (724), Expect = 1e-75
 Identities = 311/1235 (25%), Positives = 445/1235 (36%), Gaps = 223/1235 (18%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKDAFPT-----FSV----QLRRGPDGSIS 95
            C  WG  H+ +FD   +DF GTCNY+ A T      T     F+V    Q R  P  S  
Sbjct: 4075 CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYV 4134

Query: 96   RIIV--ELGASVVTVSEAIISVKDIGVIS-LPYT-SNGLQITPFGQSVRLVAKQLELELE 151
            R++    LG ++    + I  V+  GV++ LP + ++G      G S  L+     L++ 
Sbjct: 4135 RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 4194

Query: 152  VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG- 210
              W  +  + V +   Y G +CGLCGN D    N+ V   G  L P           PG 
Sbjct: 4195 YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAPGW 4251

Query: 211  -EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQADV 258
              +C      +    P   + Q +    C  L +            V  E F   C  DV
Sbjct: 4252 DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDV 4311

Query: 259  AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
                  G ++  C  L+ Y   C   G  +  WR+   C +  CP N  Y+ CG  C  +
Sbjct: 4312 CMGG--GDRDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGPPCPAS 4368

Query: 319  CSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGEVT 372
            C +P        C   C  GC C  G VL+       CVP+   C C  +G  +  G   
Sbjct: 4369 CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGSEF 4424

Query: 373  IA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFVTT 407
             A     Q CRC  G    VCT   C                       C   G     T
Sbjct: 4425 WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 4484

Query: 408  FDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV 464
             D   + F GTC Y+L      P L  +   + V ++   S + +   +V        + 
Sbjct: 4485 LDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 4544

Query: 465  ISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVG 522
            +S      +  +G    LP++  ++     +   + + T+ GL L        +  V   
Sbjct: 4545 LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 4604

Query: 523  PQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----DPC 578
              +     GLCGN+N D  DD     G   G        W+ G      E  +     PC
Sbjct: 4605 --YAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPC 4654

Query: 579  SMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGD 638
            +  Q         C ++  T      CH  V PA +++ C+  AC  +     +C A+  
Sbjct: 4655 TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 4714

Query: 639  YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPV 698
            YV AC   G  L  WR   D C + C  ++ +     +C  +C SLS  A E   SA   
Sbjct: 4715 YVAACQAAGAQLGEWRRP-DFCPLQCPAHSHYELCGDSCPVSCPSLS--APEGCESACR- 4770

Query: 699  DGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQ 758
            +GC C D  ++     CV   QC C+ +G  + L                G +  P    
Sbjct: 4771 EGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPL----------------GEVFYP---- 4809

Query: 759  MFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPG--CVCAEGLYEN 816
                                   G  C   C+            C PG    C EG    
Sbjct: 4810 -----------------------GPECERRCE------------CGPGGHVTCQEG---- 4830

Query: 817  ADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHV 876
                C P EEC  E  GV           C    C R              C   G  H 
Sbjct: 4831 --AACGPHEECRLE-DGVQ---------ACHATGCGR--------------CLANGGIHY 4864

Query: 877  ITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLS 936
            IT DG+ +   G+C Y+LA  VC        F I+ E     N+     R +    G + 
Sbjct: 4865 ITLDGRVYDLHGSCSYVLA-QVCHPKPGDEDFSIVLEK----NAAGDLQRLLVTVAGQVV 4919

Query: 937  VVLADRNYTVTGEEPHVQLGVTPGALSLVVD---ISIPGRYNLTLIWNRHMTILIRIARA 993
             +   +  TV GE   V L V  G + +  +   + +     L L+++    +L+ I   
Sbjct: 4920 SLAQGQQVTVDGEA--VALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSP 4977

Query: 994  SQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK---ESPLCGDVSFV--TDPCS 1048
             +  LCGLCGNFNGN  DDF   +   ASS      +W+    S  CG+         C 
Sbjct: 4978 FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCL 5037

Query: 1049 LNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVA 1106
                    +   C  + +    FATC + +    Y+  CV D C     GD   LC ++A
Sbjct: 5038 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLA 5095

Query: 1107 AYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQ 1165
            AY  AC   GV V  WRT +FCP++C  ++                    HY  C    Q
Sbjct: 5096 AYTAACQAAGVAVKPWRTDSFCPLHCPAHS--------------------HYSICTRTCQ 5135

Query: 1166 PQSVPGSNIEGC-----YNCSQDEYFDHEEGVCVP 1195
                  S + GC       C  D+ F   +GVC+P
Sbjct: 5136 GSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 5170



 Score =  272 bits (696), Expect = 3e-72
 Identities = 320/1266 (25%), Positives = 464/1266 (36%), Gaps = 246/1266 (19%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQLRRGPDG----SISRII 98
            C   G  H++TFD H +DF GTC Y+ A TC  +     F+V       G    S++R+I
Sbjct: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 3713

Query: 99   -VELGASVVTVSEAIISVKDIGV-ISLPYT-SNG-LQITPFGQSVRLVAKQLELELEVVW 154
             V++    + + +    V   GV + LP   +NG ++ +  G  V +   + +  L V +
Sbjct: 3714 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVI---ETDFGLRVAY 3770

Query: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEG-------------KFLEPHKFA 201
                ++ V V   Y   MCGLCGN++G   ++F    G             + + P    
Sbjct: 3771 DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 3830

Query: 202  ALQKLDDPGEI-CTFQD-IPSTHVRQAQHARICTQLLTLVAPECSVSK----EPFVLSCQ 255
                   PG   C   D  P    ++ Q    C  L +   P  S  K    +  +  C 
Sbjct: 3831 LPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 3890

Query: 256  ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC 315
             D+      G  +  C+ +  Y   C   G  V  WR+   C + +CP N  Y+ C   C
Sbjct: 3891 FDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPM-ECPQNSHYELCADTC 3947

Query: 316  VKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGE-VT 372
               CS  +    C   C  GC C  G     L N   CVP+ QC C  +G  Y P + V 
Sbjct: 3948 SLGCSALSAPLQCPDGCAEGCQCDSGF----LYNGQACVPIQQCGCYHNGVYYEPEQTVL 4003

Query: 373  IAAC-QTCRCTLGRWV-CTERPC-PGH---------------------------CSLEGG 402
            I  C Q C C +G+ V C E  C PG                            C  +GG
Sbjct: 4004 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGG 4063

Query: 403  SFVT-----------------TFDARPYRFHGTCTYILLQS--PQLPEDGA--LMAVYDK 441
              V                  +FD R + F GTC Y+L  +  P +   G          
Sbjct: 4064 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 4123

Query: 442  SGVSHSETSLVAVVYLSRQD-KIVISQDEV--VTNNGEAKWLPYKTRN--ITVFRQTSTH 496
                +   S V VV ++     I I +DE+  V  NG    LP    +  I+V +  S  
Sbjct: 4124 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKA 4183

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L +A  FGL++       ++  VT+   + G   GLCGN + +  +D     G    +  
Sbjct: 4184 LLVA-DFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 4240

Query: 557  LFVDSWRA------------GNCPAALERETDPCSMSQLNKVCAETHCSMLLR-TGTVFE 603
            ++  SWRA            G+CP         C   +L +      C  L   TG  F 
Sbjct: 4241 IWGGSWRAPGWDPLCWDECRGSCPT--------CPEDRLEQYEGPGFCGPLSSGTGGPFT 4292

Query: 604  RCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIP 663
             CHA V P  F+K CV   C        +C AL  YV AC   GV++  WR+ V  C I 
Sbjct: 4293 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEIT 4351

Query: 664  CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC 723
            C  N+ +      C  +C S +   T        V+GC C  G  L+             
Sbjct: 4352 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS------------- 4398

Query: 724  ILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGA 783
                     A++   +N       NG              C A  T+      SE     
Sbjct: 4399 ---------ADRCVPLN-------NG------------CGCWANGTYHEA--GSEFWADG 4428

Query: 784  ACAPTCQMLATG--VACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAE 841
             C+  C+    G  + C P  C  G VC  GL  +    C P     C+           
Sbjct: 4429 TCSQWCRCGPGGGSLVCTPASCGLGEVC--GLLPSGQHGCQPVSTAECQ----------- 4475

Query: 842  LHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGV 901
                                         +G+ H +T DG RF F G CEY+L+    G 
Sbjct: 4476 ----------------------------AWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGP 4507

Query: 902  NDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLA---DRNYTVTGEEPHV--QLG 956
                  F +   N   G+  V+ +R++ + +   S+ L+    R   V G    +  QL 
Sbjct: 4508 PLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLD 4567

Query: 957  VTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETR 1016
                A     D+ +     L+L ++    + +R+  A    LCGLCGN+N +  DD +  
Sbjct: 4568 SLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAV 4627

Query: 1017 SRYVASSELELVNSWKESPLCGDV--SFVTDPCSLNAFRRSWAERKCSVINSQ--TFATC 1072
                A  ++           CG+        PC+            C VI++     A C
Sbjct: 4628 GGKPAGWQVGGAQG------CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPC 4681

Query: 1073 HSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYC 1131
            H  V    Y++ C+ DAC     G    LC AVA Y  AC   G  + +WR P FCP+ C
Sbjct: 4682 HGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQC 4739

Query: 1132 GFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP--SQPQSVPGSNIEGCYNCSQDEYFDHE 1189
                      H  Y+   + +C     P  CP  S P+    +  EGC  C  D  F   
Sbjct: 4740 --------PAHSHYELCGD-SC-----PVSCPSLSAPEGCESACREGCV-C--DAGFVLS 4782

Query: 1190 EGVCVP 1195
               CVP
Sbjct: 4783 GDTCVP 4788



 Score =  271 bits (694), Expect = 4e-72
 Identities = 319/1266 (25%), Positives = 464/1266 (36%), Gaps = 246/1266 (19%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQLRRGPDG----SISRII 98
            C   G  H++TFD   +DF GTC Y+ A TC  +     F+V       G    S++R+I
Sbjct: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 1311

Query: 99   -VELGASVVTVSEAIISVKDIGV-ISLPYT-SNG-LQITPFGQSVRLVAKQLELELEVVW 154
             V++    + + +    V   GV + LP   +NG ++ +  G  V +   + +  L V +
Sbjct: 1312 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVI---ETDFGLRVAY 1368

Query: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
                ++ V V   Y  QMCGLCGN++G   ++F    G      ++F    +   P   C
Sbjct: 1369 DLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 1428

Query: 214  T--------FQDIPSTHV------RQAQHARICTQLLTLVAPECSVSK----EPFVLSCQ 255
                      +D   +H       ++ Q    C  L +   P  S  K    +  +  C 
Sbjct: 1429 LPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 1488

Query: 256  ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC 315
             D+      G  +  C+ +  Y   C   G  V  WR+   C + +CP N  Y+ C   C
Sbjct: 1489 FDLCLGG--GNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPM-ECPPNSHYELCADTC 1545

Query: 316  VKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGE-VT 372
               CS  +    C   C  GC C  G     L N   CVP+ QC C  +G  Y P + V 
Sbjct: 1546 SLGCSALSAPPQCQDGCAEGCQCDSGF----LYNGQACVPIQQCGCYHNGVYYEPEQTVL 1601

Query: 373  IAAC-QTCRCTLGR-WVCTERPC-PGH---------------------------CSLEGG 402
            I  C Q C C  G+  VC E  C PG                            C  +GG
Sbjct: 1602 IDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGG 1661

Query: 403  SFVT-----------------TFDARPYRFHGTCTYILLQS--PQLPEDGA--LMAVYDK 441
              V                  +FD R + F GTC Y+L  +  P +   G          
Sbjct: 1662 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 1721

Query: 442  SGVSHSETSLVAVVYLSRQD-KIVISQDEV--VTNNGEAKWLPYKTRN--ITVFRQTSTH 496
                +   S V VV ++     I I +DE+  V  NG    LP    +  I+V +  S  
Sbjct: 1722 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 1781

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L +A  FGL++       ++  VT+   + G   GLCGN + +  +D     G    +  
Sbjct: 1782 LLVA-DFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 1838

Query: 557  LFVDSWRA------------GNCPAALERETDPCSMSQLNKVCAETHCSMLLR-TGTVFE 603
            ++  SWRA            G+CP         C   +L +      C  L   TG  F 
Sbjct: 1839 IWGGSWRAPGWDPLCWDECRGSCPT--------CPEDRLEQYEGPGFCGPLAPGTGGPFT 1890

Query: 604  RCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIP 663
             CHA V P  F+K CV   C        +C AL  YV AC   GV++  WR+ V  C I 
Sbjct: 1891 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEIT 1949

Query: 664  CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC 723
            C  N+ +      C  +C S +   T        V+GC C  G  L+             
Sbjct: 1950 CPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS------------- 1996

Query: 724  ILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGA 783
                     A++   +N       NG              C A  T+      SE     
Sbjct: 1997 ---------ADRCVPLN-------NG------------CGCWANGTYHEA--GSEFWADG 2026

Query: 784  ACAPTCQMLATG--VACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAE 841
             C+  C+    G  + C P  C  G VC  GL  +    C P     C+           
Sbjct: 2027 TCSQWCRCGPGGGSLVCTPASCGLGEVC--GLLPSGQHGCQPVSTAECQ----------- 2073

Query: 842  LHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGV 901
                                         +G+ H +T DG RF F G CEY+L+    G 
Sbjct: 2074 ----------------------------AWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGP 2105

Query: 902  NDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLA---DRNYTVTGEEPHV--QLG 956
                  F +   N   G+  V+ +R++ + +   S+ L+    R   V G    +  QL 
Sbjct: 2106 PLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLD 2165

Query: 957  VTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETR 1016
                A     D+ +     L+L ++    + +R+  A    LCGLCGN+N +  DD +  
Sbjct: 2166 SLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAV 2225

Query: 1017 SRYVASSELELVNSWKESPLCGDV--SFVTDPCSLNAFRRSWAERKCSVINSQ--TFATC 1072
                A  ++           CG+        PC+            C VI++     A C
Sbjct: 2226 GGKPAGWQVGGAQG------CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPC 2279

Query: 1073 HSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYC 1131
            H  V    Y++ C+ DAC     G    LC AVA Y  AC   G  + +WR P FCP  C
Sbjct: 2280 HGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQC 2337

Query: 1132 GFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP--SQPQSVPGSNIEGCYNCSQDEYFDHE 1189
                      H  Y+   + +C     P  CP  S P+    +  EGC  C  D  F   
Sbjct: 2338 --------PAHSHYELCGD-SC-----PGSCPSLSAPEGCESACREGCV-C--DAGFVLS 2380

Query: 1190 EGVCVP 1195
               CVP
Sbjct: 2381 GDTCVP 2386



 Score =  271 bits (693), Expect = 6e-72
 Identities = 318/1266 (25%), Positives = 464/1266 (36%), Gaps = 246/1266 (19%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQLRRGPDG----SISRII 98
            C   G  H++TFD   +DF GTC Y+ A TC  +     F+V       G    S++R+I
Sbjct: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVI 2512

Query: 99   -VELGASVVTVSEAIISVKDIGV-ISLPYT-SNG-LQITPFGQSVRLVAKQLELELEVVW 154
             V++    + + +    V   GV + LP   +NG ++ +  G  V +   + +  L V +
Sbjct: 2513 TVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVI---ETDFGLRVAY 2569

Query: 155  GPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
                ++ V V   Y   MCGLCGN++G   ++F    G      ++F    +   P   C
Sbjct: 2570 DLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPC 2629

Query: 214  T--------------FQDIPSTHVRQAQHARICTQLLTLVAPECSVSK----EPFVLSCQ 255
                            ++ P    ++ Q    C  L +   P  S  K    +  +  C 
Sbjct: 2630 LPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCI 2689

Query: 256  ADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSAC 315
             D+      G  +  C+ +  Y   C   G  V  WR+   C + +CP N  Y+ C   C
Sbjct: 2690 FDLCLGG--GNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPM-ECPQNSHYELCADTC 2746

Query: 316  VKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGE-VT 372
               CS  +    C   C  GC C  G     L N   CVP+ QC C  +GA Y P + V 
Sbjct: 2747 SLGCSALSAPLQCPDGCAEGCQCDSGF----LYNGQACVPIQQCGCYHNGAYYEPEQTVL 2802

Query: 373  IAAC-QTCRCTLGRWV-CTERPC-PGH---------------------------CSLEGG 402
            I  C Q C C +G+ V C E  C PG                            C  +GG
Sbjct: 2803 IDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGG 2862

Query: 403  SFVT-----------------TFDARPYRFHGTCTYILLQS--PQLPEDGA--LMAVYDK 441
              V                  +FD R + F GTC Y+L  +  P +   G          
Sbjct: 2863 QGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKN 2922

Query: 442  SGVSHSETSLVAVVYLSRQD-KIVISQDEV--VTNNGEAKWLPYKTRN--ITVFRQTSTH 496
                +   S V VV ++     I I +DE+  V  NG    LP    +  I+V +  S  
Sbjct: 2923 QNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKA 2982

Query: 497  LQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTAS 556
            L +A  FGL++       ++  VT+   + G   GLCGN + +  +D     G    +  
Sbjct: 2983 LLVA-DFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIP 3039

Query: 557  LFVDSWRA------------GNCPAALERETDPCSMSQLNKVCAETHCSMLLR-TGTVFE 603
            ++  SWRA            G+CP         C   +L +      C  L   TG  F 
Sbjct: 3040 IWGGSWRAPGWDPLCWDECRGSCPT--------CPEDRLEQYEGPGFCGPLAPGTGGPFT 3091

Query: 604  RCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCTIP 663
             CHA V P  F+K CV   C        +C AL  YV AC   GV++  WR+ V  C I 
Sbjct: 3092 TCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQV-GCEIT 3150

Query: 664  CTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTYLNQKGECVRKAQCPC 723
            C  N+ +      C  +C S +   T        V+GC C  G  L+             
Sbjct: 3151 CPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLS------------- 3197

Query: 724  ILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPKTFKSCSQSSENKFGA 783
                     A++   +N       NG              C A  T+      SE     
Sbjct: 3198 ---------ADRCVPLN-------NG------------CGCWANGTYHEA--GSEFWADG 3227

Query: 784  ACAPTCQMLATG--VACVPTKCEPGCVCAEGLYENADGQCVPPEECPCEFSGVSYPGGAE 841
             C+  C+    G  + C P  C  G VC  GL  +    C P     C+           
Sbjct: 3228 TCSQWCRCGPGGGSLVCTPASCGLGEVC--GLLPSGQHGCQPVSTAECQ----------- 3274

Query: 842  LHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGV 901
                                         +G+ H +T DG RF F G CEY+L+    G 
Sbjct: 3275 ----------------------------AWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGP 3306

Query: 902  NDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLA---DRNYTVTGEEPHV--QLG 956
                  F +   N   G+  V+ +R++ + +   S+ L+    R   V G    +  QL 
Sbjct: 3307 PLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLD 3366

Query: 957  VTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETR 1016
                A     D+ +     L+L ++    + +R+  A    LCGLCGN+N +  DD +  
Sbjct: 3367 SLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAV 3426

Query: 1017 SRYVASSELELVNSWKESPLCGDV--SFVTDPCSLNAFRRSWAERKCSVINSQ--TFATC 1072
                A  ++           CG+        PC+            C VI++     A C
Sbjct: 3427 GGKPAGWQVGGAQG------CGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPC 3480

Query: 1073 HSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYC 1131
            H  V    Y++ C+ DAC     G    LC AVA Y  AC   G  + +WR P FCP  C
Sbjct: 3481 HGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQC 3538

Query: 1132 GFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP--SQPQSVPGSNIEGCYNCSQDEYFDHE 1189
                      H  Y+   + +C     P  CP  S P+    +  EGC  C  D  F   
Sbjct: 3539 --------PAHSHYELCGD-SC-----PGSCPSLSAPEGCESACREGCV-C--DAGFVLS 3581

Query: 1190 EGVCVP 1195
               CVP
Sbjct: 3582 GDTCVP 3587



 Score =  263 bits (672), Expect = 2e-69
 Identities = 258/1054 (24%), Positives = 404/1054 (38%), Gaps = 195/1054 (18%)

Query: 44   QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
            +C  WG  H+ T D H +DF GTC Y+ +A C         F+V +     GS +     
Sbjct: 4473 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 4532

Query: 96   RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
             + +++    +T+S        + GV ++LP+  + L       +  +V     L L   
Sbjct: 4533 SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSL--A 4590

Query: 154  WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
            +  DS + + V   Y   +CGLCGN++    ++  +  GK        A       GE C
Sbjct: 4591 FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 4645

Query: 214  TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
              +  PS    + Q +      C  +     P       V    +   C  D  A    G
Sbjct: 4646 VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 4703

Query: 266  PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
                 C  ++ Y   C   G  +  WR P  C + QCPA+  Y+ CG +C  +C +    
Sbjct: 4704 HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAP 4762

Query: 324  HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---------- 373
              C S+C  GC C  G VL+      TCVPV QC C+  G  Y  GEV            
Sbjct: 4763 EGCESACREGCVCDAGFVLS----GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 4818

Query: 374  ------------AAC---QTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGT 418
                        AAC   + CR   G   C    C G C   GG    T D R Y  HG+
Sbjct: 4819 CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 4877

Query: 419  CTYILLQ--SPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
            C+Y+L Q   P+ P D     V +K+     +  LV V        + ++Q + VT +GE
Sbjct: 4878 CSYVLAQVCHPK-PGDEDFSIVLEKNAAGDLQRLLVTVA----GQVVSLAQGQQVTVDGE 4932

Query: 477  AKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNF 536
            A  LP     + V  +   ++ + T+ GL L+          +++   FRG+  GLCGNF
Sbjct: 4933 AVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDA--HLLMSIPSPFRGRLCGLCGNF 4989

Query: 537  NGDTTDDFTTSMGIAEGTASLFVDSWRAGN-------------CPAALERETDPCSMSQL 583
            NG+ +DDF    G A  +   F  +WRA               CP  L  ET P   ++ 
Sbjct: 4990 NGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEA 5049

Query: 584  NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
                    C  L      F  C A ++P+ ++++CVY  C  +     +C +L  Y  AC
Sbjct: 5050 --------CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAAC 5101

Query: 644  SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
               GV +  WR+    C + C  ++ +S  ++ C+ +C +LS   T C  +    +GC C
Sbjct: 5102 QAAGVAVKPWRTD-SFCPLHCPAHSHYSICTRTCQGSCAALSG-LTGC--TTRCFEGCEC 5157

Query: 704  PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
             D   L+Q G C+    C C   G +++    S + +  +  C                 
Sbjct: 5158 DDRFLLSQ-GVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERC----------------- 5198

Query: 764  CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
                    SCS SS                 G+ C    C PG VC              
Sbjct: 5199 --------SCSSSS-----------------GLTCQAAGCPPGRVC-------------- 5219

Query: 824  PEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQR 883
                             E+  + R C  +RG             C L    ++ TFDG R
Sbjct: 5220 -----------------EVKAEARNCWATRG------------LCVLSVGANLTTFDGAR 5250

Query: 884  FVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRN 943
                    Y L++   G+ ++ P ++++ E  IC        +    F  G+  +  ++ 
Sbjct: 5251 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKG 5310

Query: 944  YTVTG---EEPHVQLGVTPGALSLVVDISIPGRYNLTL-IW-NRHMTILIRIARASQDPL 998
              V G   + P  +L     ++S   D S+  R    + +W   +  + + ++      L
Sbjct: 5311 VWVNGLRVDLPAEKLASV--SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKL 5368

Query: 999  CGLCGNFNGNMKDDFETRSRYVASSELELVNSWK 1032
            CG CGNF+G+  +D+        S E   +  W+
Sbjct: 5369 CGACGNFDGDQTNDWHD------SQEKPAMEKWR 5396



 Score =  250 bits (639), Expect = 1e-65
 Identities = 217/779 (27%), Positives = 330/779 (42%), Gaps = 96/779 (12%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAATCK--DAFPTFSVQLRRGPDGSISRIIVELG 102
            C   G  H++TFD   YD  GTC+Y     C   D  P FSV+ +    GS  R +  +G
Sbjct: 472  CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGS--RRVSYVG 529

Query: 103  ASVVTVSEAIISVK--DIGVISLPYTSNGLQITPFGQSVRLVAKQLELELEVVWGP---- 156
               V      +S+   ++G + +    + L ++     +R+        +E+V+G     
Sbjct: 530  LVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTY 589

Query: 157  --DSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFL-EPHKFAALQKLDDPGEIC 213
              D  L + +  ++  Q+CGLCGN++G   ++F++ +G    +  +FA+  KLDD   +C
Sbjct: 590  DWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLC 649

Query: 214  ---TFQDIPSTHVRQAQH---ARICTQLLTLVAP----ECSVSKEPFVLSCQADVAAAPQ 263
                  + P+    QAQH    R+C  L  L  P      ++   PF+  C  D+     
Sbjct: 650  EDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV-- 707

Query: 264  PGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN-- 321
             G + S C  LS Y++ C  +G  V  WRSP  C +  CPAN  Y+ CG AC  +C+   
Sbjct: 708  GGERLSLCRGLSAYAQACLELGISVGDWRSPANCPL-SCPANSRYELCGPACPTSCNGAA 766

Query: 322  -PQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTIA--ACQ- 377
             P +     C  GC C  G V    ++   CVP + C C   G   APG+   A   CQ 
Sbjct: 767  APSNCSGRPCVEGCVCLPGFV----ASGGACVPASSCGCTFQGLQLAPGQEVWADELCQR 822

Query: 378  --TCRCTLGRWVCTER-PCP-------------------GHCSLEGGSFVTTFDARPYRF 415
              TC     +  C ++  CP                   G C   G     +FD R + F
Sbjct: 823  RCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDF 882

Query: 416  HGTCTYILL----QSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQD--E 469
             GTCTY+L+    Q+  LP    L+    +   + S T  V V   +R  K+ + ++   
Sbjct: 883  MGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVE--ARGVKVAVRREYPG 940

Query: 470  VVTNNGEAKWLPYKTRN--ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVT--VGPQF 525
             V  +   ++LP++  +  + VFRQ      + T FGL +       + A VT  V   +
Sbjct: 941  QVLVDDVLQYLPFQAADGQVQVFRQ-GRDAVVRTDFGLTVTYD----WNARVTAKVPSSY 995

Query: 526  RGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERETDPCSMSQLNK 585
                 GLCGNFNGD  DD     G     A  F +SW+    P      T+P    +L+ 
Sbjct: 996  AEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGC--GATEPGDCPKLDS 1053

Query: 586  VCAE-----THCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYV 640
            + A+       C +L      F  CH+ ++P    + CVY  C        +C AL  Y 
Sbjct: 1054 LVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYA 1113

Query: 641  HACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSL---SDRATECHHSAVP 697
             AC   G  +  WRS  + C + C  ++ +   S  C  +C  L       +ECH     
Sbjct: 1114 AACQAAGATVHPWRSE-ELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECH----- 1167

Query: 698  VDGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGI--TCHCINGRL-SC 753
             +GC C +G  L+ +  C+  A C C+ +G      +      G    CHC  G L SC
Sbjct: 1168 -EGCVCDEGFALSGE-SCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSC 1224



 Score =  169 bits (429), Expect = 2e-41
 Identities = 157/578 (27%), Positives = 247/578 (42%), Gaps = 64/578 (11%)

Query: 31   RLKDSPQT--APDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQL 86
            RL+D  Q   A   G+C   G  H+ T D  VYD  G+C+Y+ A  C  K     FS+ L
Sbjct: 4840 RLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL 4899

Query: 87   RRGPDGSISRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQL 146
             +   G + R++V +   VV++++      D   ++LP     +++T  G+++ L   Q 
Sbjct: 4900 EKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL---QT 4956

Query: 147  ELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-HKFAALQK 205
               L +++  D+HL++ +   + G++CGLCGNF+G  +++FV   G        F A  +
Sbjct: 4957 TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 5016

Query: 206  LDDP----GEICTFQDIP---STHVRQAQHARICTQLLTLVAP----ECSVSKEPFVLSC 254
                    GE C  Q  P   +      +    C QL     P    +  +S   +   C
Sbjct: 5017 APGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQC 5076

Query: 255  QADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSA 314
              D+ A  Q G +   C +L+ Y+  C   G  V+ WR+   C +  CPA+  Y  C   
Sbjct: 5077 VYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL-HCPAHSHYSICTRT 5133

Query: 315  CVKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT 372
            C  +C+  +    C++ C  GC C +  +L    +   C+PV  C C  H   Y P   +
Sbjct: 5134 CQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDCGCT-HNGRYLPVNSS 5188

Query: 373  I----------------AACQTCRCTLGRWVC----TERPC---PGHCSLEGGSFVTTFD 409
            +                  CQ   C  GR VC      R C    G C L  G+ +TTFD
Sbjct: 5189 LLTSDCSERCSCSSSSGLTCQAAGCPPGR-VCEVKAEARNCWATRGLCVLSVGANLTTFD 5247

Query: 410  ARPYRFHGTCTYIL-LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV-ISQ 467
                       Y L  + P L        V  +  + H +T  V  V++  QD +V ++ 
Sbjct: 5248 GARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTP 5307

Query: 468  DEVVTNNGEAKWLP-YKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFR 526
            ++ V  NG    LP  K  +++V R     L +    G++  V L    +  V V     
Sbjct: 5308 NKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHA 5365

Query: 527  GQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA 564
            G+  G CGNF+GD T+D+  S    E  A   ++ WRA
Sbjct: 5366 GKLCGACGNFDGDQTNDWHDSQ---EKPA---MEKWRA 5397



 Score =  168 bits (426), Expect = 5e-41
 Identities = 146/500 (29%), Positives = 210/500 (42%), Gaps = 82/500 (16%)

Query: 763  SCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCV 822
            SC A   ++ C        G AC  +C   A    C    C  GCVC  G   +  G CV
Sbjct: 744  SCPANSRYELC--------GPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASG-GACV 794

Query: 823  PPEECPCEFSGVSYPGGAELHTD--C-RTCSCS--------RGRWACQQGTHCP------ 865
            P   C C F G+    G E+  D  C R C+C+        R + +C  G  C       
Sbjct: 795  PASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLL 854

Query: 866  -------STCTLYGEGHVITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICG 918
                    TC   G+ H ++FDG+RF F G C Y+L    CG N + P F++L EN   G
Sbjct: 855  GCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGS-CGQNAALPAFRVLVENEHRG 913

Query: 919  NSGVTCSRAIKIFLGGLSVVLADRNYT----VTGEEPHVQLGVTPGALSLVV---DISIP 971
            +  V+ +RA+++   G+ V +  R Y     V     ++      G + +     D  + 
Sbjct: 914  SQTVSYTRAVRVEARGVKVAVR-REYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVR 972

Query: 972  GRYNLTLIWNRHMTILIRIARASQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSW 1031
              + LT+ ++ +  +  ++  +  + LCGLCGNFNG+  DD   R    A++ L   NSW
Sbjct: 973  TDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSW 1032

Query: 1032 KES--PLCGDVSFVTDP--C----SLNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPY 1081
            +E   P CG     T+P  C    SL A ++  ++ +C ++      F  CHSK+     
Sbjct: 1033 QEETRPGCG----ATEPGDCPKLDSLVA-QQLQSKNECGILADPKGPFRECHSKLDPQGA 1087

Query: 1082 YEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQD 1140
               CV D C     G    LCDA+A YA AC   G  V  WR+   CP+ C  ++ +   
Sbjct: 1088 VRDCVYDRCLLP--GQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEAC 1145

Query: 1141 GHGEYQYTQEANCTWHYQPCLCPSQPQSVPGSNIEGCY-NCSQDEYFDHEEGVCVP---- 1195
             +G         C     P  C   P  VPG     C+  C  DE F      C+P    
Sbjct: 1146 SYG---------C-----PLSCGDLP--VPGGCGSECHEGCVCDEGFALSGESCLPLASC 1189

Query: 1196 -CMPPTTPQPPTTPQLPTTG 1214
             C+   T  PP     P  G
Sbjct: 1190 GCVHQGTYHPPGQTFYPGPG 1209



 Score =  135 bits (340), Expect = 5e-31
 Identities = 119/435 (27%), Positives = 177/435 (40%), Gaps = 45/435 (10%)

Query: 374 AACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLPEDG 433
           AA Q C+   G+  C        C  +G    TTFD R Y   GTC+Y +++     ED 
Sbjct: 450 AAGQRCQVVGGKAGCVAEST-AVCRAQGDPHYTTFDGRRYDMMGTCSYTMVEL--CSEDD 506

Query: 434 ALMAVYDKSGVSHSETSLVAVVYL----SRQDKIVISQDEV----VTNNGEAKWLPYKTR 485
            L A   ++   H  +  V+ V L    +    + +++ EV    V N      +     
Sbjct: 507 TLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEG 566

Query: 486 NITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTTDDFT 545
            + V+ Q+     +   FGL  VV      Q  +++  +F+ Q  GLCGN+NGD  DDF 
Sbjct: 567 RLRVY-QSGPRAVVELVFGL--VVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFL 623

Query: 546 TSMGIAEGTASLFVDSWRAGN----CPAALERETDPCSMSQLNKVCAETHCSMLLRTGTV 601
           T  G     A  F  SW+  +    C    +     C+  Q      +  C ML +    
Sbjct: 624 TPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGP 683

Query: 602 FERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGVLLWGWRSSVDNCT 661
           F  CH T++P PF ++CVY  C        +C  L  Y  AC   G+ +  WRS   NC 
Sbjct: 684 FAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPA-NCP 742

Query: 662 IPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVP-VDGCNCPDGTYLNQKGECVRKAQ 720
           + C  N+ +     AC  +C   +  A   + S  P V+GC C  G ++   G CV  + 
Sbjct: 743 LSCPANSRYELCGPACPTSC---NGAAAPSNCSGRPCVEGCVCLPG-FVASGGACVPASS 798

Query: 721 CPCILEGYKFI---------LAEQSTVING----ITCHCINGRLSCPQ----RPQMFLAS 763
           C C  +G +           L ++    NG    +TC     + SCP       Q  L  
Sbjct: 799 CGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTC---RDKQSCPAGERCSVQNGLLG 855

Query: 764 CQAPKTFKSCSQSSE 778
           C  P  F +C  S +
Sbjct: 856 CY-PDRFGTCQGSGD 869



 Score =  127 bits (320), Expect = 1e-28
 Identities = 108/383 (28%), Positives = 166/383 (43%), Gaps = 64/383 (16%)

Query: 846  CRTCSCSRGRWACQ-----QGTHCPST--CTLYGEGHVITFDGQRFVFDGNCEYILATDV 898
            C    C+ G+  CQ      G    ST  C   G+ H  TFDG+R+   G C Y +  ++
Sbjct: 444  CEGMQCAAGQ-RCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMV-EL 501

Query: 899  CGVNDSQPTFKILTENVICGNSGVTC---------SRAIKIFLGGLSVVLADRNYTVTGE 949
            C  +D+ P F +  +N   G+  V+          S ++ +  G +  VL D       +
Sbjct: 502  CSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDN------Q 555

Query: 950  EPHVQLGVTPGALSL-------VVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGLC 1002
               + + ++ G L +       VV++     + L + ++    + + +    QD +CGLC
Sbjct: 556  RSRLPVSLSEGRLRVYQSGPRAVVELV----FGLVVTYDWDCQLALSLPARFQDQVCGLC 611

Query: 1003 GNFNGNMKDDFETRSRYVASSELELVNSWKESP---LCGDVSFVTDP-CSLNAFRRSWAE 1058
            GN+NG+  DDF T    +A   +E  +SWK      LC D      P C+    +    +
Sbjct: 612  GNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGD 671

Query: 1059 RKCSVIN--SQTFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKG 1116
            R C ++      FA CH  +   P+ E CV D C    GG+   LC  ++AYAQACL+ G
Sbjct: 672  RLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVV--GGERLSLCRGLSAYAQACLELG 729

Query: 1117 VCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEA---NCTWHYQPCLCPSQPQSVPGS 1172
            + V DWR+PA CP+ C          +  Y+    A   +C     P  C  +P      
Sbjct: 730  ISVGDWRSPANCPLSC--------PANSRYELCGPACPTSCNGAAAPSNCSGRP------ 775

Query: 1173 NIEGCYNCSQDEYFDHEEGVCVP 1195
             +EGC  C     F    G CVP
Sbjct: 776  CVEGCV-CLPG--FVASGGACVP 795


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  302 bits (773), Expect = 3e-81
 Identities = 367/1225 (29%), Positives = 535/1225 (43%), Gaps = 146/1225 (11%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATL 1259
            T+ +  ++P      S PT   P  G++    +  ST P  SS  +  S T         
Sbjct: 485  TSTEASSSPPTAEVNSMPTST-PSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVT 543

Query: 1260 TSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTS 1319
            TSS+ ++SS          TP+ TS   PT+T    +T  T    +TR   S+ + +TTS
Sbjct: 544  TSSEASSSS---------TTPEGTS--IPTSTPSEGSTPLTNMPVSTRLVVSSEA-STTS 591

Query: 1320 TAQSTTRTTMTLPTPATSGTSP----TLPKSTNQELPGTTATQ----TTGPRPTPASTTG 1371
            T  + + T +T  + A+S ++     ++P ST  E  GTT T     TT    + AST  
Sbjct: 592  TTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSER-GTTITSMSVSTTLVASSEASTLS 650

Query: 1372 PTTPQPGQPTRPTATETTQTRTTTEYTT-PQTPHTTHSPPTAGSPVPSTGPVTATSFHAT 1430
             TTP        T+TE T + TT E T+ P + +T  S P    PV +T      S  A+
Sbjct: 651  -TTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTT---LVASSEAS 706

Query: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSA-SNHSAPTGTIPPPTT 1489
            T   TP    T       P +TS    S+ T  T   A M TS  S  S P  ++P   T
Sbjct: 707  TLSTTPVDTST-------PVTTSTEASSSPT--TADGASMPTSTPSEGSTPLTSMPVSKT 757

Query: 1490 L--KATGSTHTAPPITPTTSGTSQAHSSFSTNKTP-TSLHSHTSSTHHPEVT--PTSTTT 1544
            L   +  ST +  P+  +T  T+   +S S   T  TS+   T S   P +T  P S T 
Sbjct: 758  LLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITP 817

Query: 1545 ITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPT 1604
            +T    ST + TPV                ++SP T S+  SS+      +   T+TY  
Sbjct: 818  VTSPEASTLSTTPV---------------DSNSPVTTSTEVSSSPTPAEGTSMPTSTYSE 862

Query: 1605 PSHPQTTLPTHVPPFSTSLV-TPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATG 1663
               P T++P      +TS + T ST  V T T    +T A      +     PT+    G
Sbjct: 863  GRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEG 922

Query: 1664 STHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGT 1723
            ST        TT   S    +L+     TS    TS+   +  T+   T+I  +  S GT
Sbjct: 923  STPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGT 982

Query: 1724 PPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS-------TSTTSITPNHTST 1776
             P+T T    +   +S ++  ++T + S+T  T   E +S       TS  + TP+  ST
Sbjct: 983  TPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGST 1042

Query: 1777 G-TRTPVAHT---TSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHP 1832
              TR PV+ T   +S TS+   TP  T +P T  +  SS+      +   T+TY   S P
Sbjct: 1043 PLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTP 1102

Query: 1833 HTTLPTHVPSFSTSLVTPS----THTVIIPTHTQMATSASIHSMPT---GTIPPPTTIKA 1885
             T++P      ST LV  S      T  + T   + TS    S PT   GT   PT+  +
Sbjct: 1103 LTSVPV-----STRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT-SIPTSPPS 1156

Query: 1886 TGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTS---STHHPEVTPTSTTNITPKH 1942
             G+T  A     TT   S   ++ ST    +     TS   S+  P    TS    TP  
Sbjct: 1157 EGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGE 1216

Query: 1943 TSTG-TRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTA--TSFQTTTTYPT 1997
             ST  T  PV HT  ASS  S L T     S P  +S  +S+ P TA  TS  T+TT   
Sbjct: 1217 RSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTT--- 1273

Query: 1998 PSHPQTTLPTHVPPFSTSLVTPSTHTVIIT---THTQMATSASIHSTPT---GTVPPPTT 2051
                 +TL T +P  +T + +P   T++ T   T   + TS  + S+PT   GT  P +T
Sbjct: 1274 --SEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTST 1331

Query: 2052 LKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISS-----SSWLPQNSSSRPPSSP 2106
                 +  T+ P+  T   +S      +T   +S+ +++     SS      +S P S+P
Sbjct: 1332 YSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNP 1391

Query: 2107 I--TTQLPHLSSATTPVSTTNQLSSSFSP-SPSAPSTVSSYVPSSHSSPQ-----TSSPS 2158
               TT L  +  +TTPV ++   + S +P   S P T S+   SS ++ +     TS+PS
Sbjct: 1392 SEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPS 1451

Query: 2159 VGTSSSFVSAPVHSTTLSSGSHSSLSTHP--------TTASVSASPLFPSSPAASTTIRA 2210
             G  +   S PV +T +++   S+LST P        T+ +VS+SP    +PA  T+I  
Sbjct: 1452 EG-KTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSP----TPAEGTSIAI 1506

Query: 2211 TLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTT 2270
            + P   S+  T    +P+ST TV+ +  + L S+T A  STP TT S       SS  TT
Sbjct: 1507 STPSEGSTALT---SIPVSTTTVASSEINSL-STTPAVTSTPVTTYS-----QASSSPTT 1557

Query: 2271 SRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPT----TRFLTSSLTAH 2326
            +  TS+ T   + G   LTS    +P S  T L       TLS T       +T+S  A 
Sbjct: 1558 ADGTSMQTSTYSEGSTPLTS----LPVS--TMLVVSSEANTLSTTPIDSKTQVTASTEAS 1611

Query: 2327 GSTPASAPVSSLGTPTPTSPGVCSV 2351
             ST A     ++ TP+  SP + S+
Sbjct: 1612 SSTTAEGSSMTISTPSEGSPLLTSI 1636



 Score =  300 bits (769), Expect = 9e-81
 Identities = 363/1260 (28%), Positives = 544/1260 (43%), Gaps = 180/1260 (14%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTI-------------GLLSSTGPSPSSNHTP 1246
            T    P    +P T S  T   P T   T++              +L ST P  SS  + 
Sbjct: 2593 TLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEAST 2652

Query: 1247 AS--PTQTPLLPATLT-----------SSKPTASSGEPPRPTTAVTPQATSGLPPTATLR 1293
             S  P  T  L  T T           SS PT++ GE   P T +    T      A+  
Sbjct: 2653 LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTL 2712

Query: 1294 STATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQ---- 1349
            ST    T T  TT A AS+ SP T         T     TP TS    TLP ++++    
Sbjct: 2713 STTPVDTSTPVTTSAEASS-SPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTV 2771

Query: 1350 -------ELPGTTATQ----------TTGPRPTPASTTGPTTPQPGQPTRPTATET-TQT 1391
                    +P TT+T+          T+ P  TP+ T+ P T  P   T   ++E  T +
Sbjct: 2772 STTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLS 2831

Query: 1392 RTTTEYTTPQTPHT--THSPPTA-GSPVP----STGPVTATSFHATTTYPTPSHPETTLP 1444
             T  + +TP T  T  + SP TA G  VP    S G    TS   +TT P  S   +TL 
Sbjct: 2832 TTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTT-PVASSEASTLS 2890

Query: 1445 THVPPFSTSL-VTPSTHTVITPTHAQMAT----SASNHSAP-----TGTIPPPTTLKATG 1494
            T   P  TS+ VT ST    +PT A+  +    + S  S P       T+P   +  +T 
Sbjct: 2891 T--TPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTL 2948

Query: 1495 STHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRT 1554
            ST      TP T  TS   SS  T    TS+   T       +T  S +T+         
Sbjct: 2949 STTPVDTRTPVT--TSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTM--------- 2997

Query: 1555 RTPVAHTNSATSSRPPP----PFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQT 1610
              PVA + ++T SR P     P TT S    SSP ++ G     S  +  + P  S P +
Sbjct: 2998 --PVASSEASTLSRTPADTSTPVTT-STEASSSPTTAEGTGIPISTPSEGSTPLTSIPVS 3054

Query: 1611 TLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT---GTIPPPTTLKATGSTHT 1667
            T P  +P  ST   TP        +++ + TS  + S PT   GT  P +T  + GST  
Sbjct: 3055 TTPVAIPEASTLSTTP------VDSNSPVVTSTEVSSSPTPAEGTSMPISTY-SEGSTPL 3107

Query: 1668 APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMT 1727
                  TT  TS A+S+L+T    TS    TS+  H+  T++  T++  +  S G+ P+T
Sbjct: 3108 TGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLT 3167

Query: 1728 VTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTG-------TRT 1780
                 T    SS  +  ++T + + T  T   E TS++T   T   TST        T  
Sbjct: 3168 YMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSV 3227

Query: 1781 PVAHTTSATSSRL---PTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLP 1837
            PV++T  A+S       TP  +++P T +T  SS+ P    +   T+T    S P T++P
Sbjct: 3228 PVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMP 3287

Query: 1838 ---THVPSFSTSLV--TPSTHTVIIPTHTQMATSASIH---SMPTGTIPPPTTIKATGST 1889
               T V S  TS +  TP+  +  + T++Q ++S  I    SMPT T        + GST
Sbjct: 3288 VSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTY-------SEGST 3340

Query: 1890 HTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRT 1949
                    TT   S   S+ ST    TS P  TS+      T    T+I     S GT T
Sbjct: 3341 PLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGT-T 3399

Query: 1950 PVA----HTTSASSSRLPTPFTTHSPPTGSSPF--SSTGPMTATSFQTTTTYPTPSHPQT 2003
            P+A     TT   SS + T  TT   P  S+    +ST   ++ +    T+ PT +  + 
Sbjct: 3400 PLASMPVSTTPVVSSEVNTLSTT---PVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEG 3456

Query: 2004 TLPTHVPPFSTSLVTPSTHTVIIT----THTQMATSASIHSTPT--GTVPPPTTLKATGS 2057
            + P  + P ST+ V  S  + + T    T T + TS+  +S+PT       PT+    GS
Sbjct: 3457 STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGS 3516

Query: 2058 TH-TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHL-- 2114
            T  T  P++ T   +S+  +  +T   S++F++SSS     +SS P +  +TT       
Sbjct: 3517 TPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSS----QASSSPATLQVTTMRMSTPS 3572

Query: 2115 ---SSATTPVSTTNQLSSSFSPSPSAPS-------TVSSYVPSSHSSPQT-----SSPSV 2159
               SS TT + ++  ++SS + +PS PS       T S+   S+ + P+      S+PS 
Sbjct: 3573 EGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPS- 3631

Query: 2160 GTSSSFVSAPVHSTTLSSGSHSSLSTHP--------TTASVSASPLFPSSPAASTTIRAT 2211
              S+     PV +T+++     + ST P        T+  VS+SP+ P      TT+   
Sbjct: 3632 EVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPE----GTTMPIW 3687

Query: 2212 LPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTS 2271
             P   S+P T    +P+ST  V+ +  S L++ ++   STP TT ST    + ++  +T+
Sbjct: 3688 TPSEGSTPLT---TMPVSTTRVTSSEGSTLSTPSVV-TSTPVTT-STEAISSSATLDSTT 3742

Query: 2272 RSTSLTTRVPTSGFVSL--TSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGST 2329
             S S+   + T G   L  T+ VT  P S   ++ + +   +++  +   +S  T  G+T
Sbjct: 3743 MSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGTT 3802



 Score =  297 bits (760), Expect = 1e-79
 Identities = 359/1263 (28%), Positives = 543/1263 (42%), Gaps = 153/1263 (12%)

Query: 1194 VPCMPPTTPQPPTTP-------QLPTTGSRPTQVWPM-TGTSTTIGLLSSTGPSPSSNHT 1245
            V  MP +TP   +TP         P   S  + +      TST +   + T  SP++   
Sbjct: 1206 VTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEG 1265

Query: 1246 PASPTQTPLLPATLTSSKPTASS--GEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQ 1303
             + PT T    +TL +S P +++    P   T   TP  T G  P  T    ++ PT  +
Sbjct: 1266 TSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKG--PVVTSNEVSSSPTPAE 1323

Query: 1304 ATTRATASTA---SPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPG--TTATQ 1358
             T+  T++ +   +P T+    +T   +  +   +T+    + P +T+ E     TT+  
Sbjct: 1324 GTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEG 1383

Query: 1359 TTGPRPTPASTTGPTTPQPGQPTRPTATE-TTQTRTTTEYTTPQTP--HTTHSPPTAG-- 1413
            T+ P   P+  T P T  P   T   ++E +T + T  + +TP T     T SP TA   
Sbjct: 1384 TSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGI 1443

Query: 1414 ---SPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1470
               +  PS G     S   + T P  +   +TL T  P  S S V  ST    +PT A+ 
Sbjct: 1444 SIPTSTPSEGKTPLKSIPVSNT-PVANSEASTLST-TPVDSNSPVVTSTAVSSSPTPAEG 1501

Query: 1471 ATSA----SNHSAPTGTIPPPTTLKATG---STHTAPPITPTTSGTSQAHSSFSTNKTPT 1523
             + A    S  S    +IP  TT  A+    S  T P +T T   T    SS  T    T
Sbjct: 1502 TSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGT 1561

Query: 1524 SLHSHTSSTHHPEVT--PTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTG 1581
            S+ + T S     +T  P ST  +  +  +T + TP+      T+S      TT    + 
Sbjct: 1562 SMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSM 1621

Query: 1582 SSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMAT 1641
            +    S G    TS   +TT P  S   +TL T  P  S S V  ST    +PT A+   
Sbjct: 1622 TISTPSEGSPLLTSIPVSTT-PVASPEASTLST-TPVDSNSPVITSTEVSSSPTPAEGT- 1678

Query: 1642 SASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSST 1701
                 SMPT T          G T        TT   S A+S+L+T     S    TS+ 
Sbjct: 1679 -----SMPTSTY-------TEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTE 1726

Query: 1702 HHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEV 1761
              +  T++  T++  +  S GT P+T     T+   SS ++  ++T + + T  T   E 
Sbjct: 1727 ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEA 1786

Query: 1762 TSTSTT----SITPNHTSTG----TRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTG 1813
            TS+ TT    SI  +  S G    T TPV+HT  A S          +    TTP+ S  
Sbjct: 1787 TSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSE---------ASTLSTTPVDSNS 1837

Query: 1814 PVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMP 1873
            PV  ++    ++ PTP+   T++ T  PS  ++ +T       IP  T    S+  +++ 
Sbjct: 1838 PVVTST--AVSSSPTPAEG-TSIATSTPSEGSTALTS------IPVSTTTVASSETNTLS 1888

Query: 1874 TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS--TSLPYHTSSTHHPEVT 1931
            T     P       +T+     +PTT+  S  P+S         TS+P  T++    E+ 
Sbjct: 1889 T----TPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEIN 1944

Query: 1932 PTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT 1991
              STT          TRTPV   + ASSS  PT     S PT +    ST P+T+    T
Sbjct: 1945 TLSTT-------LADTRTPVTTYSQASSS--PTTADGTSMPTPAYSEGST-PLTSMPLST 1994

Query: 1992 TTTYPTPSHPQTTLPTHVP-PFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPT 2050
            T    + +   +T P     P +TS    S+ T    T  Q +T +   +TP   +P  T
Sbjct: 1995 TLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSE-RTTPLAGMPVST 2053

Query: 2051 TL--KATGSTHTAPPMTVTTSGTSQTHSSFS-TATASSSFISSSSWLPQNSSSRPPSSPI 2107
            TL   + G+T +  P+   T  T+ T +S S TA  SS  IS+ S            SP+
Sbjct: 2054 TLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPS----------EGSPL 2103

Query: 2108 TTQLPHLSSATTPVSTTNQLSSSFSP----SPSAPST--VSSYVPSSHSSPQTSSPSVGT 2161
             T +P    +TTPV++    + S +P    SP   ST   SS +P+  +S QTS+ S   
Sbjct: 2104 LTSIP---LSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYS-DR 2159

Query: 2162 SSSFVSAPVHSTTLSSGSHSSLSTHP--TTASVSASPLFPSSPAAS--TTIRATLPHTIS 2217
             +   S PV +T ++S + S+LST P  T+  V+ S    SSP  S  T++  + P   S
Sbjct: 2160 RTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGS 2219

Query: 2218 SPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQ------STTS 2271
            +PFT    +P+ST+ V  + +S L S+T    STP TT++  T+   +++      ST S
Sbjct: 2220 TPFT---SMPVSTMPVVTSEASTL-SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLS 2275

Query: 2272 RSTSLTTRVPTSGFVSLTSGVTGIPTSPV-------TNLTTRHPGPTLSPTTRFLTSSLT 2324
              T+  T +P S  +   S V+ + T+PV       T+     P PT   T+  + +S +
Sbjct: 2276 EGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTS--MPTSTS 2333

Query: 2325 AHGSTP-----------ASAPVSSLG-TPTPTSPGVCSVREQQEEITFKGCMANVTVTRC 2372
            + G+TP           AS   S+L  TP  TS  V +  +     T     +  T T  
Sbjct: 2334 SEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYS 2393

Query: 2373 EGA 2375
            EG+
Sbjct: 2394 EGS 2396



 Score =  293 bits (749), Expect = 2e-78
 Identities = 359/1279 (28%), Positives = 528/1279 (41%), Gaps = 175/1279 (13%)

Query: 1190 EGVCVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASP 1249
            EG   P     T  P +TP   +T        P+T  S  +  +   G   S+  T    
Sbjct: 2905 EGSSSPTTAEGTSMPISTPSEVST--------PLT--SILVSTVPVAGSEASTLSTTPVD 2954

Query: 1250 TQTPLLPATLTSSKPTASSGE------PPRPTTAVTPQATSGLPPTATLRSTATKPTVTQ 1303
            T+TP+  +   SS PT + G       P    T +T  + S +P  ++  ST +      
Sbjct: 2955 TRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLS------ 3008

Query: 1304 ATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPR 1363
               R  A T++P TTST  S++ TT         GT   +   +    P T+   +T P 
Sbjct: 3009 ---RTPADTSTPVTTSTEASSSPTT-------AEGTGIPISTPSEGSTPLTSIPVSTTPV 3058

Query: 1364 PTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTT-PQTPHTTHSPPTAGSPVPSTGPV 1422
              P ++T  TTP        T+TE + + T  E T+ P + ++  S P  G PV ST PV
Sbjct: 3059 AIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPV-STTPV 3117

Query: 1423 TATSFHATTTYP----------TPSHPE------TTLPTHVP----------PFSTSLVT 1456
            T+++    +T P          T +H        T++PT  P          P ST LV 
Sbjct: 3118 TSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVV 3177

Query: 1457 PSTHTVI------TPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTS 1510
             S  + +      T T    +T A++ +   GT  P +T     +  T+ P++ T   +S
Sbjct: 3178 SSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASS 3237

Query: 1511 QAHSSFST---NKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTR-TRTPVAHT---NS 1563
            +A    +T   + TP +  +  SS+  P    TS  T TP+  ST  T  PV+ T   +S
Sbjct: 3238 EASILSTTPVDSNTPLTTSTEASSSP-PTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASS 3296

Query: 1564 ATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLP-THVPPFSTS 1622
             TS+    P  T +P T  S  SS+ P+   +   T+TY   S P T +  +  P  S+ 
Sbjct: 3297 ETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSE 3356

Query: 1623 LVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQAL 1682
              T ST  V T T    +T AS+          PT+  + G+T   P  ++  S T    
Sbjct: 3357 ASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTT---PLASMPVSTTPVVS 3413

Query: 1683 SSLNTAKTSTSLHSHTSSTHHAEATSTST----TNITPNPTSTGTPPMTV----TTSGTS 1734
            S +NT  T T + S+T  T   EA+S+ T    T++  + TS G+ P+++    TT   S
Sbjct: 3414 SEVNTLST-TPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVAS 3472

Query: 1735 QSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTR---------TPVAHT 1785
               S+ ST    TS    TSS  +   T+   TS+  +    G+          TPVA +
Sbjct: 3473 SEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASS 3532

Query: 1786 TSATSSRLPTP---FTTHSPPTGTTPIS-----------STGPVTATSFQTTTTY----- 1826
             ++T S  P     F T S    ++P +           S G  + T+   ++TY     
Sbjct: 3533 EASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSE 3592

Query: 1827 -PTPSHPHTTLPTHVPSFSTSLVTPSTHTVI-IPTHTQMATSASIHSMPTGTIPPPTTIK 1884
              TPS P     T V + + S  TP+   VI +P  T    S  +  MP  T     TI 
Sbjct: 3593 ASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTS--VTIS 3650

Query: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT--PTSTTNITPKH 1942
              G+  T P  T T   TS   SS       T++P  T S     +T  P STT +T   
Sbjct: 3651 EAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSE 3710

Query: 1943 TST------GTRTPVAHTTSASSSRLPTPFTTHS------------------PPTGSSPF 1978
             ST       T TPV  +T A SS      TT S                   P    P 
Sbjct: 3711 GSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPE 3770

Query: 1979 SSTG--PMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST-HTVIITTHTQMATS 2035
            SST   P   TS   TT     S P T   T   P ST+    +   TV+I+  + M+ S
Sbjct: 3771 SSTPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPS 3830

Query: 2036 -ASIHSTPTGTVPPP--TTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSS 2092
             AS  STP G    P  T+ KA   +  A   T+  S TS+  +  +T   S++    +S
Sbjct: 3831 EASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTL--PTS 3888

Query: 2093 WLPQNSSSRPPSSPITTQLPHLSSATTP-VSTTNQLSSSFSPSPSAPSTVSSYVPSSHSS 2151
            +   + +S PP    TT  P   +A+TP +     +S S     S P T + ++PS+  +
Sbjct: 3889 FPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGT-TIFIPSTPVT 3947

Query: 2152 PQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLF--PSSPAASTTIR 2209
              T+     T+ +  +  + ST L++ S SS ST   T S S +  F  P+   A+    
Sbjct: 3948 SSTADVFPATTGAVSTPVITSTELNTPSTSSSST---TTSFSTTKEFTTPAMTTAAPLTY 4004

Query: 2210 ATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQST 2269
             T+    S+P T S     S  T+S T + H ++S    P TP + +S          ST
Sbjct: 4005 VTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSR--------PST 4056

Query: 2270 TSRSTSLTTRVPTSGFVSLTSGVTGIPTSP--VTNLTTRHPGPTLSPTTRFLTSSLTAHG 2327
             +  T   T  P       T+  +    +P  VT +TTR    T   TT F T + TA  
Sbjct: 4057 ITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPST--RTTSFPTVTTTA-- 4112

Query: 2328 STPASAPVSSLGTPTPTSP 2346
              P +  + S  T TPT P
Sbjct: 4113 -VPTNTTIKSNPTSTPTVP 4130



 Score =  291 bits (745), Expect = 5e-78
 Identities = 344/1263 (27%), Positives = 540/1263 (42%), Gaps = 166/1263 (13%)

Query: 1200 TTPQPPTTPQLPTTG--SRPTQVWPMTGTS-------------TTIGLLSSTGPSPSSNH 1244
            TTP    +P + +T   S PT   P  GTS             T+I + ++T  S  +N 
Sbjct: 1830 TTPVDSNSPVVTSTAVSSSPT---PAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNT 1886

Query: 1245 TPASP--TQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVT 1302
               +P  T TP+      SS PT + G    PT+  TP+   G PP  ++  + T    +
Sbjct: 1887 LSTTPAVTSTPVTTYAQVSSSPTTADGSS-MPTS--TPR--EGRPPLTSIPVSTTTVASS 1941

Query: 1303 QATTRAT--ASTASPATTSTAQSTTRTTM---TLPTPATS-GTSP--TLPKSTNQELPGT 1354
            +  T +T  A T +P TT +  S++ TT    ++PTPA S G++P  ++P ST   +   
Sbjct: 1942 EINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSE 2001

Query: 1355 TATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQT-PHTTHSPPTAG 1413
             +T +T    TP  T+ P T         T+TE + + TT   T+ QT   +  + P AG
Sbjct: 2002 ASTLST----TPVDTSTPAT---------TSTEGSSSPTTAGGTSIQTSTPSERTTPLAG 2048

Query: 1414 SPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTH-AQMAT 1472
             PV +T      S    T   TP   +T +       S++    S+ T+  P+  + + T
Sbjct: 2049 MPVSTT---LVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLT 2105

Query: 1473 SASNHSAPTGTIPPPTTLKATGSTHTAPPITPT--------TSGTSQAHSSFSTNKTP-T 1523
            S    + P  + P  +TL  T     +P IT T        T GTS   S++S  +TP T
Sbjct: 2106 SIPLSTTPVAS-PEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLT 2164

Query: 1524 SLHSHTSSTHHPEVTPTSTTTI-TPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGS 1582
            S+   T+      ++  STT + T  P +  T    + T S  +S P     T +P  GS
Sbjct: 2165 SMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMP-----TSTPSEGS 2219

Query: 1583 SPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATS 1642
            +PF+S            +T P  +   +TL +  P  +++ VT ST    +PT A+  TS
Sbjct: 2220 TPFTS---------MPVSTMPVVTSEASTL-SATPVDTSTPVTTSTEATSSPTTAE-GTS 2268

Query: 1643 ASIHSMPTGTIP--------------PPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTA 1688
                ++  GT P                +TL  T      P  T T + +    +   + 
Sbjct: 2269 IPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSM 2328

Query: 1689 KTSTSLHSHTSSTHHAEAT----STSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAK 1744
             TSTS   +T  T    +T    S  T+ ++  P  T TP  T + +G+S + +  ++  
Sbjct: 2329 PTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388

Query: 1745 TSTSLHSHTSSTHHPEVTSTSTTSITPNHTST--GTRTPVAHTTSATSSRLP---TPFTT 1799
            TST     T  T  P  T    +S    H++T   T TPV  +T A+SS      T   T
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPT 2448

Query: 1800 HSPPTGTTPIS----STGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTV 1855
              P  GTTP++    ST PV ++   T +T P  +    T  T   S  T     +   +
Sbjct: 2449 SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPT-----TAEDI 2503

Query: 1856 IIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
            ++P  T    S  + S+P  T P  +   +T ST      +P  + T  S S+ S   TS
Sbjct: 2504 VVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTS 2563

Query: 1916 TSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPV----AHTTSASSSRLPTPFTTHSP 1971
                 ++  +      P ST  +     ST + TPV      TTS  +S  PT     S 
Sbjct: 2564 MPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623

Query: 1972 PTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQ 2031
            P  S+P   +  +T+      +T P  S   +TL T  P  + +LVT ST T    T  +
Sbjct: 2624 PI-STPSEVSTSLTSI---LVSTMPVASSEASTLST-TPVDTRTLVTTSTGTSSSPTTAE 2678

Query: 2032 ---MATSA-SIHSTPTGTVPPPTTLKAT--GSTHTAPPMTVTTSGTSQTHSSFSTATASS 2085
               M TS     STP   +   TTL A    ST +  P+  +T  T+   +S S  TA  
Sbjct: 2679 GSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEG 2738

Query: 2086 SFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVST---------TNQLSSSFSPSPS 2136
            + +  S+    +  S P +S + + LP  SS  + VST         T    +S SP+ +
Sbjct: 2739 TSMRIST---PSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTA 2795

Query: 2137 APSTVSSYVPSSHSSPQTSSP------------SVGTSSSFVSAPVHSTTLSSGSHSSLS 2184
              +++ +  PS  S+P TS P            ++ T+    S PV ++T +S S ++  
Sbjct: 2796 EVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE 2855

Query: 2185 --THPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVT---VSPTPS- 2238
                P + +   S L  S P ++T + ++   T+S+   +   +P++T T    SPT + 
Sbjct: 2856 GIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTT-PVDTSIPVTTSTEGSSSPTTAE 2914

Query: 2239 -SHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPT 2297
             + +  ST +  STP T+    T P   S+++T  +T + TR P +     +S  T   T
Sbjct: 2915 GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPT---T 2971

Query: 2298 SPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLG-TPTPTSPGVCSVREQQE 2356
            +  T++    PG   +P T    S++       AS+  S+L  TP  TS  V +  E   
Sbjct: 2972 AEGTSMPISTPGERRTPLTSMSVSTMPV-----ASSEASTLSRTPADTSTPVTTSTEASS 3026

Query: 2357 EIT 2359
              T
Sbjct: 3027 SPT 3029



 Score =  291 bits (745), Expect = 5e-78
 Identities = 354/1233 (28%), Positives = 539/1233 (43%), Gaps = 128/1233 (10%)

Query: 1188 HEEGVCVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPA 1247
            + EG       P +  P  + +  T  + P        TST      +T    S   +P 
Sbjct: 2392 YSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPP 2451

Query: 1248 SPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQ--AT 1305
            S   TPL    + S+ P  SS      T + TP  TS   P  T    ++ PT  +    
Sbjct: 2452 SEGTTPLASMPV-STTPVVSS---EAGTLSTTPVDTS--TPMTTSTEASSSPTTAEDIVV 2505

Query: 1306 TRATASTASPATTSTAQSTTRT----TMTLPTPATSGTSPTLPKSTNQELPGTTATQTTG 1361
              +TAS  S   TS   STT        TL T      SP +  ST      T+A  T+ 
Sbjct: 2506 PISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVV-TSTEISSSATSAEGTSM 2564

Query: 1362 PRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTT----PQTPHTTHSPPTA---GS 1414
            P  T +  + P    P   T+P A+    T +TT   T      +  T+ SP TA     
Sbjct: 2565 PTSTYSEGSTPLRSMP-VSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSM 2623

Query: 1415 PVPSTGPV-TATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQ---M 1470
            P+ +   V T+ +    +T P  S   +TL T  P  + +LVT ST T  +PT A+   M
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLST-TPVDTRTLVTTSTGTSSSPTTAEGSSM 2682

Query: 1471 ATSA-SNHSAPTGTIPPPTTLKAT--GSTHTAPPITPTTSGTSQAHSSFS-TNKTPTSLH 1526
             TS     S P   I   TTL A    ST +  P+  +T  T+ A +S S T    TS+ 
Sbjct: 2683 PTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMR 2742

Query: 1527 SHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFS 1586
              T S     +T    +T+           PVA + ++T S         S P  +S  +
Sbjct: 2743 ISTPSDGSTPLTSILVSTL-----------PVASSEASTVSTTA---VDTSIPVTTSTEA 2788

Query: 1587 STGPMTA--TSFKTTTTYPTPSHPQTTLP-THVPPFSTSLVTPSTHTVITPTHAQMATSA 1643
            S+ P TA  TS  T+T   T S P T++P  H P  S+   T ST  V T T    +T A
Sbjct: 2789 SSSPTTAEVTSMPTSTPSET-STPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKA 2847

Query: 1644 SIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHH 1703
            S        I  P +  + GST        TT   S   S+L+T    TS+   TS+   
Sbjct: 2848 SSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGS 2907

Query: 1704 AEATSTSTTNI-TPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVT 1762
            +  T+   T++    P+   TP  ++  S    + S  ST  T T + + T  T   E +
Sbjct: 2908 SSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLST-TPVDTRTPVTTSAEAS 2966

Query: 1763 STSTTS-------------ITPNHTSTGTRTPVAHTTSATSSRLP----TPFTTHSPPTG 1805
            S+ TT+              TP  + + +  PVA + ++T SR P    TP TT S    
Sbjct: 2967 SSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTT-STEAS 3025

Query: 1806 TTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMAT 1865
            ++P ++ G     S  +  + P  S P +T P  +P  ST   TP      + +++ + T
Sbjct: 3026 SSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTP------VDSNSPVVT 3079

Query: 1866 SASIHSMPT---GTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHT 1922
            S  + S PT   GT  P +T     +  T  P++ TT  TS + S+ ST    TS P  T
Sbjct: 3080 STEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVS-TTPVTSSAISTLSTTPVDTSTPVTT 3138

Query: 1923 SSTHHPEVTPTSTTNITPKHTSTGTRTPVAH--------TTSASSSRLPTPFTTHSPPTG 1974
            S+  H   T +  T++ P  T +   TP+ +         +S  S+   TP  T +P T 
Sbjct: 3139 STEAHSSPTTSEGTSM-PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTT 3197

Query: 1975 SSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITT----HT 2030
            S+  +S+     TS  T+    TPS   T L +   P S + V  S  +++ TT    +T
Sbjct: 3198 STEATSSTTAEGTSIPTS----TPSEGMTPLTS--VPVSNTPVASSEASILSTTPVDSNT 3251

Query: 2031 QMATSASIHSTP---TGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSS- 2086
             + TS    S+P    GT  P +T     +  T+ P++ TT  +S+T S+ ST  A +S 
Sbjct: 3252 PLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSET-STLSTTPADTST 3310

Query: 2087 ----FISSSSWLPQNSSSRPPSSPI---TTQLPHLSSATTPVSTTNQLSSSFSP----SP 2135
                +  +SS  P    +  P+S     +T L ++S +TTPV ++   + S +P    +P
Sbjct: 3311 PVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTP 3370

Query: 2136 SAPSTVSSYVPSS--HSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVS 2193
               ST +S  P++   +S  TSSPS GT +   S PV +T + S   ++LST P  ++  
Sbjct: 3371 VTTSTEASLSPTTAEGTSIPTSSPSEGT-TPLASMPVSTTPVVSSEVNTLSTTPVDSNTL 3429

Query: 2194 ASPLFPSSPAASTTIRATLP-HTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTP 2252
             +    +S + +     +LP  T S   T  +++P+ST  V+ + +S L S+T    STP
Sbjct: 3430 VTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTL-STTPVDTSTP 3488

Query: 2253 RTTAS-THTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPT 2311
             TT+S T+++P      TT+  TS+ T     G   LT+    + T+PV +        T
Sbjct: 3489 VTTSSPTNSSP------TTAEVTSMPTSTAGEGSTPLTN--MPVSTTPVASSEASTLSTT 3540

Query: 2312 LSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPT 2344
               +  F+TSS  A  S+PA+  V+++   TP+
Sbjct: 3541 PVDSNTFVTSSSQA-SSSPATLQVTTMRMSTPS 3572



 Score =  291 bits (744), Expect = 7e-78
 Identities = 358/1215 (29%), Positives = 522/1215 (42%), Gaps = 153/1215 (12%)

Query: 1200 TTPQPPTTP-QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPAT 1258
            TTP+  + P   P+ GS P    P++         S+T  +P+ ++T  + +      +T
Sbjct: 553  TTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSST 612

Query: 1259 LTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKP--------TVTQATTRATA 1310
                    +S    R TT  +   ++ L  ++   + +T P        T T+AT+ +T 
Sbjct: 613  TAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTT 672

Query: 1311 S--TASPATTSTAQSTTRTTMTLPTPATSG------------TSPTLPKSTNQELPGTTA 1356
            +  T+ P +T T  ST  T+M + T   +             TS  +  ST      TTA
Sbjct: 673  AEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTA 732

Query: 1357 TQTTGPRPTPASTTGPTTPQPGQPTRPTATE-----TTQTRTTTEYTT-------PQTPH 1404
               + P  TP+  + P T  P   T  T++E     TT   T+T  TT       P T  
Sbjct: 733  DGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTE 792

Query: 1405 TTHSP---PTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHT 1461
             T  P   P+ GSP+ ++ PV+ T        P  S   +TL T  P  S S VT ST  
Sbjct: 793  GTSMPISTPSEGSPLLTSIPVSIT--------PVTSPEASTLST-TPVDSNSPVTTSTEV 843

Query: 1462 VITPTHAQ---MATSA-SNHSAPTGTIPPPTTLKATG--STHTAPPI---TPTTSGTSQA 1512
              +PT A+   M TS  S    P  ++P  TTL AT   ST +  P+   TP T+ T +A
Sbjct: 844  SSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNST-EA 902

Query: 1513 HSSFSTNKTPTSLHSHTSSTHHPEVT--PTSTTTI------TPNPTSTRTRTPVAHTNSA 1564
             SS +T++  TS+ + T       +T  P STT +      T + T   T TPV  +  A
Sbjct: 903  RSSPTTSEG-TSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEA 961

Query: 1565 TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLV 1624
            TSS  P      S PT S+P   T P+T+T    T    + +   +T P      S + +
Sbjct: 962  TSS--PTTAEGTSIPT-STPSEGTTPLTSTPVSHTLVANSEASTLSTTPVD----SNTPL 1014

Query: 1625 TPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSS 1684
            T ST     P  A+        SMPT T        + GST        TT   S   S+
Sbjct: 1015 TTSTEASSPPPTAEGT------SMPTST-------PSEGSTPLTRMPVSTTMVASSETST 1061

Query: 1685 LNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAK 1744
            L+T    TS    T  T +++A+S+ST                 T  GTS   S++S  +
Sbjct: 1062 LSTTPADTS----TPVTTYSQASSSST-----------------TADGTSMPTSTYS--E 1098

Query: 1745 TSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPT 1804
             ST L S   ST     +  ST S TP  TS    T    ++S T++   T   T  P  
Sbjct: 1099 GSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAE-GTSIPTSPPSE 1157

Query: 1805 GTTPISSTGPVTAT---SFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHT 1861
            GTTP++S  PV+ T   S +  T   TP    T + T   S   S   P+     +PT T
Sbjct: 1158 GTTPLASM-PVSTTLVVSSEANTLSTTPVDSKTQVAT---STEASSPPPTAEVTSMPTST 1213

Query: 1862 QMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYH 1921
                S  + SMP    P  ++  +T ST      TP T  TS   SS  T    TSLP  
Sbjct: 1214 PGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVT--TSAETSSSPTTAEGTSLPTS 1271

Query: 1922 TSSTHHPEVT--PTSTTNITPKHTSTGTRTPV----AHTTSASSSRLPTPFTTHSPPTGS 1975
            T+S     +T  P STT +T    ST   TPV       TS   S  PTP    S PT +
Sbjct: 1272 TTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTST 1331

Query: 1976 SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPT-HVPPFSTSLVTPSTHTVIITTHTQMAT 2034
                 T P+T+    TT    +     +T P  +  P +TS    S+ T   +  T M  
Sbjct: 1332 YSEGRT-PLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTT--SEGTSMPN 1388

Query: 2035 S-ASIHSTPTGTVPPPTT--LKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSS 2091
            S  S  +TP  ++P  TT  + +  ST +A P+  +T GT+   ++ S  TA    I +S
Sbjct: 1389 SNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTS 1448

Query: 2092 SWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSS 2151
            +  P    +   S P+ +  P  +S  + +STT     S SP  ++ +  SS  P+  +S
Sbjct: 1449 T--PSEGKTPLKSIPV-SNTPVANSEASTLSTTP--VDSNSPVVTSTAVSSSPTPAEGTS 1503

Query: 2152 PQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRAT 2211
               S+PS G S++  S PV +TT++S   +SLST P   S   +    +S + +T    +
Sbjct: 1504 IAISTPSEG-STALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTS 1562

Query: 2212 L-PHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTT 2270
            +   T S   T    LP+ST+ V  + ++ L  ST    S  + TAST      +S STT
Sbjct: 1563 MQTSTYSEGSTPLTSLPVSTMLVVSSEANTL--STTPIDSKTQVTASTE-----ASSSTT 1615

Query: 2271 SRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTP 2330
            +  +S+T   P+ G   LTS        PV+      P  +   TT   ++S     +  
Sbjct: 1616 AEGSSMTISTPSEGSPLLTS-------IPVSTTPVASPEASTLSTTPVDSNSPVITSTEV 1668

Query: 2331 ASAPVSSLGTPTPTS 2345
            +S+P  + GT  PTS
Sbjct: 1669 SSSPTPAEGTSMPTS 1683



 Score =  289 bits (740), Expect = 2e-77
 Identities = 362/1286 (28%), Positives = 543/1286 (42%), Gaps = 141/1286 (10%)

Query: 1211 PTTGSRPTQVWPMTGTSTTIGLLSSTGPS------PSSNHTPASPTQTPLLPATLTSSKP 1264
            P T S      P T  STTI   +++  S      P+S    AS     LL   +  S P
Sbjct: 187  PLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTP 246

Query: 1265 -TASSGEPPRPTTAVTPQATSGLP-----PTATLRSTATKPTVTQATTRAT--ASTASPA 1316
             T S+     PTTA  P  ++  P     P   +  +      ++A+T +T  A+T  P 
Sbjct: 247  VTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPV 306

Query: 1317 TTSTAQSTTRTT---MTLPTPA-TSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372
             TST  S++ TT    ++PT   T G++P      +     T+   T    P   ST   
Sbjct: 307  ITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVT 366

Query: 1373 TTPQPGQPTRPTATETTQ--TRTTTEYTTPQT--PHTTHSPPTAGSPVPSTGPVTATSF- 1427
            T+ +P   + PT  E T   T T +E +TP T  P +T    ++ +   ST PV + +F 
Sbjct: 367  TSTEPS--SLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFV 424

Query: 1428 -----------------HATTTYPTPSHPETTLPTHVPPFSTSLVTP-STHTVITPTHAQ 1469
                              AT+T    S P T++P    P ++S  +  ST  V + T   
Sbjct: 425  TTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVT 484

Query: 1470 MATSASNHSAPTGTI-PPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSH 1528
             +T AS+ S PT  +   PT+  + GST    P+T  +  T    SS ++  + T + + 
Sbjct: 485  TSTEASS-SPPTAEVNSMPTSTPSEGST----PLTSMSVSTMPVASSEASTLSTTPVDTS 539

Query: 1529 TSSTHHPEVTPTSTTTI-TPNPTSTRTRTPVAHTNSATSSR---PPPPFTTHSPPTGSSP 1584
            T  T   E + +STT   T  PTST +      TN   S+R        TT + P  S+ 
Sbjct: 540  TPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNT 599

Query: 1585 FSSTGPMTATSFKTT--TTYPTPSHPQTTLPTHVPPFSTSLV------TPSTHTVITPTH 1636
            F +T    ++S  T   T+ PT ++ +          ST+LV      T ST  V + T 
Sbjct: 600  FVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTP 659

Query: 1637 AQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHS 1696
               +T A+  S        PT+    GST        TT   S   S+L+T    TS   
Sbjct: 660  VTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPV 719

Query: 1697 HTSSTHHAEATSTSTTNITPNPTSTGTPPMT----VTTSGTSQSRSSFSTAKTSTSLHSH 1752
             TS+   +  T+    ++  +  S G+ P+T      T  TS   S+ ST    TS H  
Sbjct: 720  TTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHIT 779

Query: 1753 TSSTHHPEVTSTSTTSITPNHTSTG----TRTPVAHT--TSATSSRL-PTPFTTHSPPTG 1805
            TS+      T+T  TS+  +  S G    T  PV+ T  TS  +S L  TP  ++SP T 
Sbjct: 780  TSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTT 839

Query: 1806 TTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMAT 1865
            +T +SS+      +   T+TY     P T++P      +TS ++ +  T  + T T +  
Sbjct: 840  STEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAIS-TLSTTPVDTSTPVTN 898

Query: 1866 SASIHSMPTGT--IPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTS 1923
            S    S PT +     PT+    GST        TT   S    + S     TS P  TS
Sbjct: 899  STEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTS 958

Query: 1924 STHHPEVTPTSTTNITPKHTSTG----TRTPVAHT---TSASSSRLPTPFTTHSPPTGSS 1976
            +      T    T+I     S G    T TPV+HT    S +S+   TP  +++P T S+
Sbjct: 959  TEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST 1018

Query: 1977 PFSSTGPMTATSFQTTTTYPTPSHPQTTLP---THVPPFSTSLV--TPSTHTVIITTHTQ 2031
              SS  P    +   T+T    S P T +P   T V    TS +  TP+  +  +TT++Q
Sbjct: 1019 EASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQ 1078

Query: 2032 MATSA-------------SIHSTPTGTVPPPTTL--KATGSTHTAPPMTVTTSGTSQTHS 2076
             ++S+             S  STP  +VP  T L   +  ST +  P+  +   T+ T +
Sbjct: 1079 ASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEA 1138

Query: 2077 SFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSA----TTPVSTTNQLSSSFS 2132
            S S  TA  + I +S   P   ++   S P++T L   S A    TTPV +  Q+++S  
Sbjct: 1139 SSSPTTAEGTSIPTSP--PSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196

Query: 2133 PSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASV 2192
             S   P+   + +P       TS+P    S+   S PV  T ++S   S+LST P   S 
Sbjct: 1197 ASSPPPTAEVTSMP-------TSTPG-ERSTPLTSMPVRHTPVASSEASTLSTSPVDTST 1248

Query: 2193 SASPLFPSSPAASTTIRATLP-HTISSPFTLSALLPISTVTVSPTPSSHLASSTI--AFP 2249
              +    +S + +T    +LP  T S   TL   +P+ST  V+   +S L ++ +    P
Sbjct: 1249 PVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGP 1308

Query: 2250 STPRTTASTHTAPAFSSQ---STTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLT-- 2304
                   S+   PA  +    ST S   +  T +P +  +  +S ++ + T+PV N T  
Sbjct: 1309 VVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPV 1368

Query: 2305 TRHPGPTLSPTTRFLTS---SLTAHGSTP-ASAPVSSL-----------GTPTPTS-PGV 2348
            T       SPTT   TS   S  + G+TP  S PVS+             TP  TS PG 
Sbjct: 1369 TTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGT 1428

Query: 2349 CSVREQQEEITFKGCMANVTVTRCEG 2374
             S        T +G ++  T T  EG
Sbjct: 1429 TSAEATSSPTTAEG-ISIPTSTPSEG 1453



 Score =  287 bits (735), Expect = 8e-77
 Identities = 402/1491 (26%), Positives = 580/1491 (38%), Gaps = 298/1491 (19%)

Query: 1202 PQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTS 1261
            P   T+ Q  T   R T   P+T    +  +++S+  S  S  TP   T TP+  +T   
Sbjct: 2145 PTEGTSMQTSTYSDRRT---PLTSMPVSTTVVASSAISTLST-TPVD-TSTPVTNSTEAR 2199

Query: 1262 SKPTASSGE------PPRPTTAVTPQATSGLPPTATLRSTATKPTVTQAT--TRATASTA 1313
            S PT S G       P   +T  T    S +P   +  ST +   V  +T  T +T +T+
Sbjct: 2200 SSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATS 2259

Query: 1314 SPATTSTAQSTTRTTMTLPTPATS-------------GTSPTLPKSTNQELPGTTATQTT 1360
            SP T       T T     TP TS              T  T P  +N   P TT+T+ +
Sbjct: 2260 SPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNT--PFTTSTEAS 2317

Query: 1361 GPRPTPASTTGPT-------TPQPGQPTRPTATETTQTRTTTEYTTP---QTPHTTHSPP 1410
             P PT   T+ PT       TP    P   T   + +T T +  TTP    TP TT+S  
Sbjct: 2318 SPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS--TTPADTSTPVTTYSQ- 2374

Query: 1411 TAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTP--STHTVITPTHA 1468
               SP  +      TS ++  + P  S P +T+P      ST   TP  ++  V T T A
Sbjct: 2375 AGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEA 2434

Query: 1469 QMA-TSASNHSAPT-----GTIP--------PPTTLKATGSTHTAPPITPTTSGTSQAHS 1514
              + T+A   S PT     GT P         P      G+  T P  T T   TS   S
Sbjct: 2435 SSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEAS 2494

Query: 1515 SFSTNKTP---------------TSLHSHTSSTHHPEVTPTSTTTITPN-PTSTRTRTPV 1558
            S  T                   TS+   T+    PE +  STT +  N P  T T    
Sbjct: 2495 SSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISS 2554

Query: 1559 AHTNSATSSRPPPPFTTHSPPTGSSPFS------------STGPMTATSFKTTTTYPTPS 1606
            + T++  +S P   ++  S P  S P S            ST P+  TS   TT+  T S
Sbjct: 2555 SATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVD-TSIPVTTSTETSS 2613

Query: 1607 HPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMP-----------TGTIPP 1655
             P T   T +P  + S V+ S  +++  T    ++ AS  S             TGT   
Sbjct: 2614 SPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSS 2673

Query: 1656 PTTLK------ATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATST 1709
            PTT +      +T    + P   +  S T  A S  +T  T T + + T  T  AEA+S+
Sbjct: 2674 PTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST-TPVDTSTPVTTSAEASSS 2732

Query: 1710 STT----NITPNPTSTGTPPMTVTTSGT----SQSRSSFSTAKTSTSLHSHTSS------ 1755
             TT    ++  +  S G+ P+T     T    S   S+ ST    TS+   TS+      
Sbjct: 2733 PTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSP 2792

Query: 1756 ---------THHPEVTSTSTTSITPNHTSTG-------------TRTPVAHTTSATSSR- 1792
                     T  P  TST  TS+  NHT                T TPV  +T A+SS  
Sbjct: 2793 TTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPT 2852

Query: 1793 ----LPTPFTTHSP--------PTGTTPISSTGPVTA------TSFQTTTTYPTPSHPHT 1834
                +  P +T S         P  TTP++S+   T       TS   TT+    S P T
Sbjct: 2853 TAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTT 2912

Query: 1835 TLPTHVPSFSTSLV-TPSTHTVI-----------------IPTHTQMATSASIHSMPTGT 1876
               T +P  + S V TP T  ++                 + T T + TSA   S PT  
Sbjct: 2913 AEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTA 2972

Query: 1877 IPPPTTIKATGSTHTAPPMTPTTSGT----SQSPSSFSTAKTSTSLPYHTSSTHHPEVTP 1932
                  I   G   T  P+T  +  T    S   S+ S     TS P  TS+      T 
Sbjct: 2973 EGTSMPISTPGERRT--PLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTT 3030

Query: 1933 TSTTNI---TPKHTSTG-TRTPVAHTTSA---SSSRLPTPFTTHSPPTGSSPFSSTGPMT 1985
               T I   TP   ST  T  PV+ T  A   +S+   TP  ++SP   S+  SS+    
Sbjct: 3031 AEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPA 3090

Query: 1986 ATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPT-- 2043
              +    +TY   S P T +P    P ++S ++ +  T  + T T + TS   HS+PT  
Sbjct: 3091 EGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS-TLSTTPVDTSTPVTTSTEAHSSPTTS 3149

Query: 2044 -GTVPPPTT------------------LKATGSTHTAPPMTVTTSGTSQTHSSFSTATAS 2084
             GT  P +T                  + +  ST +A P+  +T  T+ T ++ ST    
Sbjct: 3150 EGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG 3209

Query: 2085 SSFISSSSWLPQNSSSRPPSSPITTQLPHLSS-----ATTPVSTTNQLSSSFSPSPSAPS 2139
            +S  +S+     +    P +S   +  P  SS     +TTPV +   L++S   S S P+
Sbjct: 3210 TSIPTSTP----SEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPT 3265

Query: 2140 TVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFP 2199
               + +P       TS+PS G S+   S PV +TT++S   S+LST P   S   +P+  
Sbjct: 3266 AEGTSMP-------TSTPSEG-STPLTSMPVSTTTVASSETSTLSTTPADTS---TPVTT 3314

Query: 2200 SSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259
             S A+S           S P      +P ST +   TP ++++ ST    S+  +T ST 
Sbjct: 3315 YSQASS-----------SPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTT 3363

Query: 2260 ---------TAPAFSSQSTTSRSTSLTTRVPTSGFVSL-----------TSGVTGIPTSP 2299
                     T+   S   TT+  TS+ T  P+ G   L           +S V  + T+P
Sbjct: 3364 PVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTP 3423

Query: 2300 V------TNLTTRHPGPTLSPTTRFLTSSLTAHGSTP-----------ASAPVSSLGT-- 2340
            V      T  T     PT++  T   TS+ T+ GSTP           AS+  S+L T  
Sbjct: 3424 VDSNTLVTTSTEASSSPTIAEGTSLPTST-TSEGSTPLSIMPLSTTPVASSEASTLSTTP 3482

Query: 2341 -----------PTPTSPGVCSVREQQEEITFKGC--MANVTVTRCEGACISAASFNIITQ 2387
                       PT +SP    V         +G   + N+ V+    A   A++ +    
Sbjct: 3483 VDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPV 3542

Query: 2388 QVDARCSCCRPLHSYEQQLELPCPDPSTP--GRRLVLTLQVFSHCVCSSVA 2436
              +   +      S    L++     STP  G   + T+ + S  V SS A
Sbjct: 3543 DSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEA 3593



 Score =  287 bits (734), Expect = 1e-76
 Identities = 349/1229 (28%), Positives = 537/1229 (43%), Gaps = 161/1229 (13%)

Query: 1198 PPTTPQPPTTPQLPTTG-SRPTQVW-----PMTGTSTTIGLLSSTGPSPSSNHTPASPTQ 1251
            P TT    T+      G S PT  +     P+T       L++S+  S  S  TP   T 
Sbjct: 659  PVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLST-TPVD-TS 716

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATA- 1310
            TP+  +T  SS PT + G    PT+  TP  + G  P  ++  + T  T ++A+T +T  
Sbjct: 717  TPVTTSTEASSSPTTADGAS-MPTS--TP--SEGSTPLTSMPVSKTLLTSSEASTLSTTP 771

Query: 1311 -STASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPAST 1369
              T++  TTST  S + TT       T GTS  +   +      T+   +  P  +P ++
Sbjct: 772  LDTSTHITTSTEASCSPTT-------TEGTSMPISTPSEGSPLLTSIPVSITPVTSPEAS 824

Query: 1370 TGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHA 1429
            T  TTP        T+TE                        + SP P+ G         
Sbjct: 825  TLSTTPVDSNSPVTTSTE-----------------------VSSSPTPAEG--------- 852

Query: 1430 TTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASN----HSAPT---G 1482
             T+ PT ++ E   P    P ST+LV  S  + ++ T    +T  +N     S+PT   G
Sbjct: 853  -TSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEG 911

Query: 1483 TIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTN-KTPTSLHSHTSSTHHPEVTP-T 1540
            T  P +T     +  T+ P + T   +S+A +  +T   T T + + T +T  P     T
Sbjct: 912  TSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGT 971

Query: 1541 STTTITPNP-TSTRTRTPVAHT---NSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSF 1596
            S  T TP+  T+  T TPV+HT   NS  S+    P  +++P T S+  SS  P    + 
Sbjct: 972  SIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTS 1031

Query: 1597 KTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGT---- 1652
              T+T    S P T +P      ST++V  S  + ++ T A  +T  + +S  + +    
Sbjct: 1032 MPTSTPSEGSTPLTRMPV-----STTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTA 1086

Query: 1653 --IPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTS 1710
                 PT+  + GST        T    S   S+L+T    TS+   TS+   +  T+  
Sbjct: 1087 DGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAE 1146

Query: 1711 TTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHT-------SSTHHPEVTS 1763
             T+I  +P S GT P+      T+   SS +   ++T + S T       +S+  P    
Sbjct: 1147 GTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEV 1206

Query: 1764 TSTTSITPNHTSTG-TRTPVAHTTSATS--SRLPTPFTTHSPPTGTTPISSTGPVTA--T 1818
            TS  + TP   ST  T  PV HT  A+S  S L T     S P  T+  +S+ P TA  T
Sbjct: 1207 TSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGT 1266

Query: 1819 SFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVI---IPTHTQMATSASIHSMPT- 1874
            S  T+TT        +TL T +P  +T + +P   T++   + T   + TS  + S PT 
Sbjct: 1267 SLPTSTT-----SEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTP 1321

Query: 1875 --GTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTP 1932
              GT  P +T     +  T+ P+  TT   S + S  ST     S P  TS+      T 
Sbjct: 1322 AEGTSMPTSTYSEGRTPLTSIPVN-TTLVASSAISILSTTPVDNSTPVTTSTEACSSPTT 1380

Query: 1933 TSTTNITPKHTSTG----TRTPVAHT---TSASSSRLPTPFTTHSPPTGSSPFSSTGPMT 1985
            +  T++   + S G    T  PV+ T   +S +S+   TP  T +P T S+  +S+ P T
Sbjct: 1381 SEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSS-PTT 1439

Query: 1986 ATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIIT---THTQMATSASIHSTP 2042
            A      T+  TPS  +T L + +P  +T +      T+  T   +++ + TS ++ S+P
Sbjct: 1440 AEGISIPTS--TPSEGKTPLKS-IPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSP 1496

Query: 2043 T---GTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSS 2099
            T   GT    +T     +  T+ P++ TT  +S+ +S  +T   +S+ +++ S   Q SS
Sbjct: 1497 TPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYS---QASS 1553

Query: 2100 SRPPSSPITTQLPHLSSATT-----PVSTTNQLSS-----SFSPSPSAPSTVSSYVPSSH 2149
            S   +   + Q    S  +T     PVST   +SS     S +P  S     +S   SS 
Sbjct: 1554 SPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSS 1613

Query: 2150 SSPQTSSPSVGTSSS----FVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAAS 2205
            ++ + SS ++ T S       S PV +T ++S   S+LST P     S SP+  S+  +S
Sbjct: 1614 TTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVD---SNSPVITSTEVSS 1670

Query: 2206 TTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFS 2265
            +   A      +S +T     P++++TV  TP +  A ST++      +T  T +  A S
Sbjct: 1671 SPTPAEGTSMPTSTYT-EGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARS 1729

Query: 2266 SQSTTSRSTSLTTRVPTSGFVSLTS----------------GVTGIPTS-PVTNLTTRHP 2308
            S  TTS  TS+    P+ G   LTS                  T I TS PVT  T    
Sbjct: 1730 S-PTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATS 1788

Query: 2309 GPTLSPTTRFLTSSLTAHGSTP-ASAPVS 2336
             PT +  T   TS+L + G TP  S PVS
Sbjct: 1789 SPTTAEGTSIPTSTL-SEGMTPLTSTPVS 1816



 Score =  287 bits (734), Expect = 1e-76
 Identities = 363/1229 (29%), Positives = 549/1229 (44%), Gaps = 183/1229 (14%)

Query: 1197 MPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256
            MP +TP   +TP      S P    P+   S+    LS+T             T TP+  
Sbjct: 914  MPTSTPGEGSTP----LTSMPDSTTPV--VSSEARTLSAT----------PVDTSTPVTT 957

Query: 1257 ATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPA 1316
            +T  +S PT + G      T++         PT+         T ++ TT  T++  S  
Sbjct: 958  STEATSSPTTAEG------TSI---------PTS---------TPSEGTTPLTSTPVSHT 993

Query: 1317 TTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQ 1376
              + ++++T +T    TP  S T   L  ST    P  TA  T+ P  TP+  + P T  
Sbjct: 994  LVANSEASTLST----TPVDSNT--PLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRM 1047

Query: 1377 PGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTP 1436
            P   T   ++ET+   TT   T+  TP TT+S  ++ S        TA      T+ PT 
Sbjct: 1048 PVSTTMVASSETSTLSTTPADTS--TPVTTYSQASSSS-------TTADG----TSMPTS 1094

Query: 1437 SHPETTLPTHVPPFSTSLVTPSTHTVI--TP--THAQMATSASNHSAPT---GTIPPPTT 1489
            ++ E + P    P ST LV  S  + +  TP  T   + TS    S+PT   GT   PT+
Sbjct: 1095 TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGT-SIPTS 1153

Query: 1490 LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTS---STHHPEVTPTSTTTIT 1546
              + G+T  A     TT   S   ++ ST    +     TS   S+  P    TS  T T
Sbjct: 1154 PPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTST 1213

Query: 1547 PNPTST-RTRTPVAHT---NSATSSRPPPPFTTHSPPTGSSPFSSTGPMTA--TSFKTTT 1600
            P   ST  T  PV HT   +S  S+    P  T +P T S+  SS+ P TA  TS  T+T
Sbjct: 1214 PGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSS-PTTAEGTSLPTST 1272

Query: 1601 TYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIT---PTHAQMATSASIHSMPT---GTIP 1654
            T        +TL T +P  +T + +P   T++T    T   + TS  + S PT   GT  
Sbjct: 1273 T-----SEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGT-S 1326

Query: 1655 PPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI 1714
             PT+  + G T        TT   S A+S L+T     S    TS+   +  T++  T++
Sbjct: 1327 MPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSM 1386

Query: 1715 TPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTT----SIT 1770
              +  S GT P+T     T+   SS ++  ++T + + T  T   E TS+ TT    SI 
Sbjct: 1387 PNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIP 1446

Query: 1771 PNHTSTG---------TRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQ 1821
             +  S G         + TPVA++ ++T S   TP  ++SP   +T +SS+ P  A    
Sbjct: 1447 TSTPSEGKTPLKSIPVSNTPVANSEASTLS--TTPVDSNSPVVTSTAVSSS-PTPAEG-- 1501

Query: 1822 TTTTYPTPSHPHTTLPTHVPSFSTSL---------VTPSTHTVIIPTHTQMA---TSASI 1869
            T+    TPS   T L T +P  +T++          TP+  +  + T++Q +   T+A  
Sbjct: 1502 TSIAISTPSEGSTAL-TSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADG 1560

Query: 1870 HSMPTGTIPPPTT------------IKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTS 1917
             SM T T    +T            + +  +T +  P+   T  T+ + +S ST    +S
Sbjct: 1561 TSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSS 1620

Query: 1918 LPYHTSSTHHPEVT--PTSTTNITPKHTSTGTRTPVAHT----TSASSSRLPTPFTTHSP 1971
            +   T S   P +T  P STT +     ST + TPV       TS   S  PTP    S 
Sbjct: 1621 MTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSM 1680

Query: 1972 PTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTH-- 2029
            PT +     T P+T+ + +TT   P  S   +TL T     ST + T +      TT   
Sbjct: 1681 PTSTYTEGRT-PLTSITVRTT---PVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEG 1736

Query: 2030 TQMATSA-SIHSTPTGTVPPPTT--LKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSS 2086
            T M  S  S  +TP  ++P  TT  L +  ST +A P+  +T  T+ T ++ S  TA  +
Sbjct: 1737 TSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGT 1796

Query: 2087 FISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVP 2146
             I +S+       +   S+P++  L   S A+T +STT     S SP  ++ +  SS  P
Sbjct: 1797 SIPTSTL--SEGMTPLTSTPVSHTLVANSEAST-LSTTP--VDSNSPVVTSTAVSSSPTP 1851

Query: 2147 SSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHP--------TTASVSASPLF 2198
            +  +S  TS+PS G S++  S PV +TT++S   ++LST P        T A VS+SP  
Sbjct: 1852 AEGTSIATSTPSEG-STALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSP-- 1908

Query: 2199 PSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTAST 2258
              + A  +++  + P     P T    +P+ST TV+ +  + L S+T+A   TP TT S 
Sbjct: 1909 --TTADGSSMPTSTPREGRPPLT---SIPVSTTTVASSEINTL-STTLADTRTPVTTYS- 1961

Query: 2259 HTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTS---GVTGIPTSPVTNLTTRHPGPTLSPT 2315
                  SS  TT+  TS+ T   + G   LTS     T + +S  + L+T  P  T +P 
Sbjct: 1962 ----QASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTT-PVDTSTPA 2016

Query: 2316 TRFLTSSLTAHGSTPASAPVSSLGTPTPT 2344
            T     + T   S+P +A  +S+ T TP+
Sbjct: 2017 T-----TSTEGSSSPTTAGGTSIQTSTPS 2040



 Score =  284 bits (727), Expect = 7e-76
 Identities = 351/1244 (28%), Positives = 538/1244 (43%), Gaps = 134/1244 (10%)

Query: 1200 TTPQPPTTPQLPTT--GSRPTQ----VWPMTGTSTTIGLLSS----TGPSPSSNHTPASP 1249
            TTP   +TP   +T   S PT     V P++  S    LL+S    T P  SS  +  S 
Sbjct: 2832 TTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLST 2891

Query: 1250 TQT----PLLPATLTSSKPTASSGE------PPRPTTAVTPQATSGLPPTATLRST-ATK 1298
            T      P+  +T  SS PT + G       P   +T +T    S +P   +  ST +T 
Sbjct: 2892 TPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTT 2951

Query: 1299 P--TVTQATTRATAS--------TASPATTSTAQSTTRTTMTLPT-PATSGTSPTLPKS- 1346
            P  T T  TT A AS        T+ P +T   + T  T+M++ T P  S  + TL ++ 
Sbjct: 2952 PVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTP 3011

Query: 1347 TNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTAT---ETTQTRTTTEYTTPQTP 1403
             +   P TT+T+ +   PT A  TG     P + + P  +    TT        T   TP
Sbjct: 3012 ADTSTPVTTSTEASSS-PTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTP 3070

Query: 1404 HTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVI 1463
              ++SP    + V S+      +    +TY   S P T +P    P ++S ++  + T +
Sbjct: 3071 VDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPV 3130

Query: 1464 TPTHAQMATSASNHSAPTGT--IPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKT 1521
              T   + TS   HS+PT +     PT+  + GST    P+T     T    SS  +  +
Sbjct: 3131 D-TSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGST----PLTYMPVSTMLVVSSEDSTLS 3185

Query: 1522 PTSLHSHTSSTHHPEVTPTSTTTITPNPTSTR-------TRTPVAHTNSATSSRP---PP 1571
             T + + T  T   E T ++T   T  PTST        T  PV++T  A+S        
Sbjct: 3186 ATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTT 3245

Query: 1572 PFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTV 1631
            P  +++P T S+  SS+ P    +   T+T    S P T++P      ST+ V  S  + 
Sbjct: 3246 PVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPV-----STTTVASSETST 3300

Query: 1632 ITPTHAQMATSASIHSMPTGTIP------PPTTLKATGSTHTAPTMTLTTSGTSQALSSL 1685
            ++ T A  +T  + +S  + + P       PT+  + GST        TT   S   S+L
Sbjct: 3301 LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360

Query: 1686 NTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKT 1745
            +T    TS    TS+      T+   T+I  +  S GT P+      T+   SS     +
Sbjct: 3361 STTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLS 3420

Query: 1746 STSLHSHTSSTHHPEVTSTST----TSITPNHTSTGTR---------TPVAHTTSATSSR 1792
            +T + S+T  T   E +S+ T    TS+  + TS G+          TPVA + ++T S 
Sbjct: 3421 TTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLST 3480

Query: 1793 LPTPFTTHSPPTGTTPISSTGPVTA--TSFQTTT----TYPTPSHPHTTLPTHVPSFSTS 1846
              TP  T +P T ++P +S+ P TA  TS  T+T    + P  + P +T P      ST 
Sbjct: 3481 --TPVDTSTPVTTSSPTNSS-PTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTL 3537

Query: 1847 LVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSP 1906
              TP      + + +Q ++S +   + T  +  P+     GS+     +  +T  TS   
Sbjct: 3538 STTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSE----GSSSLTTMLLSSTYVTSSEA 3593

Query: 1907 SSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNI---TPKHTSTGTRTPVAHTTSASSSRLP 1963
            S+ ST     S P  TS+  +   TP     +   TP   ST        TTS + S   
Sbjct: 3594 STPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAG 3653

Query: 1964 T----PFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSH---PQTTLPTHVPPFSTS- 2015
            T    P  T +P   S+  SS+ P+T     TT    TPS    P TT+P      ++S 
Sbjct: 3654 TASTLPVDTSTPVITSTQVSSS-PVTPEG--TTMPIWTPSEGSTPLTTMPVSTTRVTSSE 3710

Query: 2016 ---LVTPS--THTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSG 2070
               L TPS  T T + T+   +++SA++ ST T +V  P  +   G+T     + V+T+ 
Sbjct: 3711 GSTLSTPSVVTSTPVTTSTEAISSSATLDST-TMSVSMPMEISTLGTT-----ILVSTTP 3764

Query: 2071 TSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSS 2130
             ++   S ST +  S + S S       SS P +   TT +P  +++      T  L S 
Sbjct: 3765 VTRFPES-STPSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISP 3823

Query: 2131 FSP-SPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTT 2189
             S  SPS  ST+S+  P   S+P  +S   G+     S P   TT+     S  ST  TT
Sbjct: 3824 ISVMSPSEASTLST-PPGDTSTPLLTSTKAGS----FSIPAEVTTIRISITSERSTPLTT 3878

Query: 2190 ASVSASPLFPSSPAASTTIRATLPHTISSPFTLSA------LLPIST-VTVSPTPSSHLA 2242
              VS + L  S P AS  I +T P   S+ FT S        +P++T ++VS        
Sbjct: 3879 LLVSTT-LPTSFPGAS--IASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTP 3935

Query: 2243 SSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTN 2302
             +TI  PSTP T+++    PA +   +T   TS     P++   S T+  +         
Sbjct: 3936 GTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPA 3995

Query: 2303 LTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTP-TPTS 2345
            +TT  P   ++ +T   T   T+ G T +++ +S+  TP T TS
Sbjct: 3996 MTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTS 4039



 Score =  282 bits (722), Expect = 2e-75
 Identities = 369/1333 (27%), Positives = 561/1333 (42%), Gaps = 190/1333 (14%)

Query: 1199 PTTPQPPTTPQLPTTGSRPTQVWPMTGTS--TTIGLLSSTGPSPSSNHTPASPTQ-TPLL 1255
            P T  P +T  + ++ +      P+   +  T     SS+  +  S+ T ++P++ +PLL
Sbjct: 1574 PLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLL 1633

Query: 1256 PATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTA-- 1313
             +   S+ P AS   P   T + TP  ++   P  T    ++ PT  + T+  T++    
Sbjct: 1634 TSIPVSTTPVAS---PEASTLSTTPVDSNS--PVITSTEVSSSPTPAEGTSMPTSTYTEG 1688

Query: 1314 -SPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPG--TTATQTTGPRPTPASTT 1370
             +P T+ T ++T   +  + T +T+    + P +T+ E     TT+  T+ P  TP+  T
Sbjct: 1689 RTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGT 1748

Query: 1371 GPTTPQPGQPTRPTATE-TTQTRTTTEYTTPQTPHT--THSPPTA-GSPVP----STGPV 1422
             P T  P   T   ++E +T + T  + +TP T  T  T SP TA G+ +P    S G  
Sbjct: 1749 TPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMT 1808

Query: 1423 TATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQ---MATSA-SNHS 1478
              TS   + T    S   T   T  P  S S V  ST    +PT A+   +ATS  S  S
Sbjct: 1809 PLTSTPVSHTLVANSEASTLSTT--PVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGS 1866

Query: 1479 APTGTIPPPTTLKATGSTHT---APPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHP 1535
                +IP  TT  A+  T+T    P +T T   T    SS  T    +S+ + T     P
Sbjct: 1867 TALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRP 1926

Query: 1536 EVT--PTSTTTI------TPNPTSTRTRTPVAHTNSATSS--------RPPPPFTTHSPP 1579
             +T  P STTT+      T + T   TRTPV   + A+SS         P P ++  S P
Sbjct: 1927 PLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSEGSTP 1986

Query: 1580 TGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTL------PTHVPPFSTSLVTPSTHTVIT 1633
              S P S+T  +++ +   +TT    S P TT       PT     S    TPS  T  T
Sbjct: 1987 LTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERT--T 2044

Query: 1634 PTHAQMATSASIHSMPTGTIPP-PTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTS- 1691
            P      ++  + S    T+   P   K   +  T  + + T  G+S  +S+ +      
Sbjct: 2045 PLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLL 2104

Query: 1692 TSLHSHTSSTHHAEATSTSTTNITPNP---TSTGTPPMTVTTSGTSQSRSSFSTAKTSTS 1748
            TS+   T+     EA++ STT +  N    TST      + T GTS   S++S  +T   
Sbjct: 2105 TSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTP-- 2162

Query: 1749 LHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLP---TPFTTHSPPTG 1805
            L S   ST     ++ ST S TP  TST    PV ++T A SS      T   T +P  G
Sbjct: 2163 LTSMPVSTTVVASSAISTLSTTPVDTST----PVTNSTEARSSPTTSEGTSMPTSTPSEG 2218

Query: 1806 TTPISS----TGPVTA------------TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVT 1849
            +TP +S    T PV              TS   TT+    S P T   T +P+ + S  T
Sbjct: 2219 STPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGT 2278

Query: 1850 ------PSTHTVI------------IPTHTQMATSASIHS---------MPTGT------ 1876
                  P +HT++            + ++T   TS    S         MPT T      
Sbjct: 2279 TPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNT 2338

Query: 1877 ----IPPPTTIKA---TGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPE 1929
                +P  TT+ A   T +  T P  T T   T     S  T    TS+P  T S     
Sbjct: 2339 PLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTP 2398

Query: 1930 VT--PTSTTNITPKHTST------GTRTPVAHTTSASSSRLP---TPFTTHSPPTGSSPF 1978
            +T  P ST  +     ST       T TPV  +T ASSS      T   T  P  G++P 
Sbjct: 2399 LTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPL 2458

Query: 1979 SS----TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQ--- 2031
            +S    T P+ ++   T +T P  +    T  T     S+S  T     V I+T ++   
Sbjct: 2459 ASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEA---SSSPTTAEDIVVPISTASEGST 2515

Query: 2032 MATSASIHSTPTGTVPPPTTLKATGSTHTAPPMT---VTTSGTSQTHSSFSTATASS--- 2085
            + TS  + +TP  + P  +TL  T     +P +T   +++S TS   +S  T+T S    
Sbjct: 2516 LLTSIPVSTTPVAS-PEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGST 2574

Query: 2086 ---SFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT------------PVSTTNQLSSS 2130
               S   S+  L  + +S   ++P+ T +P  +S  T            P+ST +++S+S
Sbjct: 2575 PLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTS 2634

Query: 2131 F-----SPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLST 2185
                  S  P A S  S+   +   +    + S GTSSS  +A   S   S+    S   
Sbjct: 2635 LTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERST-- 2692

Query: 2186 HPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASST 2245
             P T  + ++ L  +S A++    +T P   S+P T SA    S  T   T    +  ST
Sbjct: 2693 -PLTNILVSTTLLANSEASTL---STTPVDTSTPVTTSAEASSSPTTAEGT---SMRIST 2745

Query: 2246 IAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTT 2305
             +  STP T+    T P  SS+++T  +T++ T +P +     +S  T   T+ VT++ T
Sbjct: 2746 PSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPT---TAEVTSMPT 2802

Query: 2306 RHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS-PGVCSVREQQEEITFKGCM 2364
              P  T +P    LTS    H    +S   +   TP  TS P   S +      T +G +
Sbjct: 2803 STPSETSTP----LTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIV 2858

Query: 2365 ANVTVTRCEGACI 2377
              ++ T  EG+ +
Sbjct: 2859 VPIS-TASEGSTL 2870



 Score =  281 bits (719), Expect = 6e-75
 Identities = 360/1307 (27%), Positives = 541/1307 (41%), Gaps = 217/1307 (16%)

Query: 1199 PTTPQPPTTP-QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPA 1257
            PTT +  + P   P+ GS P    P+    +T+ +++S   + S+  TP   T TP+  +
Sbjct: 2202 PTTSEGTSMPTSTPSEGSTPFTSMPV----STMPVVTSEASTLSA--TPVD-TSTPVTTS 2254

Query: 1258 TLTSSKPTASSGEP-PRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPA 1316
            T  +S PT + G   P  T +      + +P + TL   A     T +TT   ++T  P 
Sbjct: 2255 TEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTL--VANSEVSTLSTTPVDSNT--PF 2310

Query: 1317 TTSTAQST---TRTTMTLPTPATS-GTSP--TLPKSTNQELPGTTATQTTGPRPTPASTT 1370
            TTST  S+   T    ++PT  +S G +P   +P ST       T+T +T    TPA T+
Sbjct: 2311 TTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLST----TPADTS 2366

Query: 1371 GPTTPQPGQPTRPTATETTQ--TRTTTEYTTPQTPHTTHSPPTAGSPVP--STGPVTATS 1426
             P T      + PT  + T   T T +E +TP T     + P   S     ST PV  TS
Sbjct: 2367 TPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVD-TS 2425

Query: 1427 FHATTTYPTPSHPETTLPTHVPPFSTSL-VTPSTHTVITPTHAQMATSASNHSAPTGTIP 1485
               TT+    S P T   T +P    S   TP     ++ T    + + +  + P  T  
Sbjct: 2426 TPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTST 2485

Query: 1486 PPTT-LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTT 1544
            P TT  +A+ S  TA  I    S  S+  +        TS+   T+    PE +  STT 
Sbjct: 2486 PMTTSTEASSSPTTAEDIVVPISTASEGSTLL------TSIPVSTTPVASPEASTLSTTP 2539

Query: 1545 ITPN-PTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFS------------STGPM 1591
            +  N P  T T    + T++  +S P   ++  S P  S P S            ST P+
Sbjct: 2540 VDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPV 2599

Query: 1592 TATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSAS------- 1644
              TS   TT+  T S P T   T +P  + S V+ S  +++  T    ++ AS       
Sbjct: 2600 D-TSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPV 2658

Query: 1645 ----IHSMPTGTIPPPTTLK------ATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSL 1694
                + +  TGT   PTT +      +T    + P   +  S T  A S  +T  T T +
Sbjct: 2659 DTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLST-TPV 2717

Query: 1695 HSHTSSTHHAEATSTST----TNITPNPTSTGTPPMTVTTSGT----SQSRSSFSTAKTS 1746
             + T  T  AEA+S+ T    T++  +  S G+ P+T     T    S   S+ ST    
Sbjct: 2718 DTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVD 2777

Query: 1747 TSLHSHTSS---------------THHPEVTSTSTTSITPNHTSTG-------------T 1778
            TS+   TS+               T  P  TST  TS+  NHT                T
Sbjct: 2778 TSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDT 2837

Query: 1779 RTPVAHTTSATSS-----RLPTPFTTHSP--------PTGTTPIS-------STGPVTAT 1818
             TPV  +T A+SS      +  P +T S         P  TTP++       ST PV  T
Sbjct: 2838 STPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVD-T 2896

Query: 1819 SFQTTTTYPTPSHPHTTLPTHVP-SFSTSLVTPSTHTVI-----------------IPTH 1860
            S   TT+    S P T   T +P S  + + TP T  ++                 + T 
Sbjct: 2897 SIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTR 2956

Query: 1861 TQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGT----SQSPSSFSTAKTST 1916
            T + TSA   S PT        I   G   T  P+T  +  T    S   S+ S     T
Sbjct: 2957 TPVTTSAEASSSPTTAEGTSMPISTPGERRT--PLTSMSVSTMPVASSEASTLSRTPADT 3014

Query: 1917 SLPYHTSSTHHPEVTPTSTTNI---TPKHTSTG-TRTPVAHTTSA---SSSRLPTPFTTH 1969
            S P  TS+      T    T I   TP   ST  T  PV+ T  A   +S+   TP  ++
Sbjct: 3015 STPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSN 3074

Query: 1970 SPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTH 2029
            SP   S+  SS+      +    +TY   S P T +P    P ++S ++ +  T  + T 
Sbjct: 3075 SPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS-TLSTTPVDTS 3133

Query: 2030 TQMATSASIHSTPT---GTVPPPTT------------------LKATGSTHTAPPMTVTT 2068
            T + TS   HS+PT   GT  P +T                  + +  ST +A P+  +T
Sbjct: 3134 TPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTST 3193

Query: 2069 SGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS-----ATTPVST 2123
              T+ T ++ ST    +S  +S+     +    P +S   +  P  SS     +TTPV +
Sbjct: 3194 PVTTSTEATSSTTAEGTSIPTST----PSEGMTPLTSVPVSNTPVASSEASILSTTPVDS 3249

Query: 2124 TNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSL 2183
               L++S   S S P+   + +P       TS+PS G S+   S PV +TT++S   S+L
Sbjct: 3250 NTPLTTSTEASSSPPTAEGTSMP-------TSTPSEG-STPLTSMPVSTTTVASSETSTL 3301

Query: 2184 STHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS 2243
            ST P   S   +P+   S A+S           S P      +P ST +   TP ++++ 
Sbjct: 3302 STTPADTS---TPVTTYSQASS-----------SPPIADGTSMPTSTYSEGSTPLTNMSF 3347

Query: 2244 STIAFPSTPRTTAS-----THTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTS 2298
            ST    S+  +T S     T T    S++++ S +T+  T +PTS   S + G T + + 
Sbjct: 3348 STTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTS---SPSEGTTPLASM 3404

Query: 2299 PVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
            PV+             TT   +++L    +  +S+P  + GT  PTS
Sbjct: 3405 PVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTS 3451



 Score =  278 bits (710), Expect = 6e-74
 Identities = 330/1199 (27%), Positives = 501/1199 (41%), Gaps = 126/1199 (10%)

Query: 1224 TGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQAT 1283
            +  +T  G  S+    P    + ++  +   + +++TS  P  SS       +  T ++T
Sbjct: 63   SAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSEST 122

Query: 1284 SGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTL 1343
            S    + TL  ++T+ T +  T   T    S  +  +  ST     T P P+    + +L
Sbjct: 123  SD---STTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYT-SL 178

Query: 1344 PKSTNQELPGTTATQTTGPRPTPASTTGP--TTPQPGQPTRPTATETTQTRTTTEYTTPQ 1401
                +   P TT+TQ +    TP STT P  T  +   P       T +  ++   T   
Sbjct: 179  TYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLT 238

Query: 1402 TPHTTHSPPT-----AGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVT 1456
            TP    +P T     + SP  + GP  + S  +  + P    P + +       ST   T
Sbjct: 239  TPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTT 298

Query: 1457 PSTHT--VITPTHAQMA-TSASNHSAPTGTI---------PPPTTLKATGSTHTAPPITP 1504
            P+     VIT T A  + T+A   S PT T           P +T+    S  +   ITP
Sbjct: 299  PAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITP 358

Query: 1505 ----TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVT--PTSTTTITPNPTSTRTRTPV 1558
                T   TS   SS  T    TS+ + T S     +T  P ST  +  +  ST +  PV
Sbjct: 359  VDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPV 418

Query: 1559 AHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPP 1618
               +S T       F T +    SSP ++     ATS  +  + P  S P +T P     
Sbjct: 419  ---DSKT-------FVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSE 468

Query: 1619 FSTSLVTP--STHTVITPTHAQMA-TSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTT 1675
             S    TP  S   V T T A  +  +A ++SMPT T        + GST        T 
Sbjct: 469  ASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTST-------PSEGSTPLTSMSVSTM 521

Query: 1676 SGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQ 1735
               S   S+L+T    TS    TSS   + +T+   T+I  +  S G+ P+T     T  
Sbjct: 522  PVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRL 581

Query: 1736 SRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPT 1795
              SS ++  ++T   S+T  T   E +S+STT+     TS  T T     T+ TS  + T
Sbjct: 582  VVSSEASTTSTTPADSNTFVTTSSEASSSSTTA---EGTSMPTSTYSERGTTITSMSVST 638

Query: 1796 PFTTHSPPT--GTTPISSTGPVT----ATSFQTT---TTYPTPSHPHTTLPTHVPSFSTS 1846
                 S  +   TTP+ S  PVT    ATS  TT   T+ PT ++   + P      +T+
Sbjct: 639  TLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTT 698

Query: 1847 LVTPS----THTVIIPTHTQMATSASIHSMPTGT--IPPPTTIKATGSTHTAPPMTPTTS 1900
            LV  S      T  + T T + TS    S PT       PT+  + GST         T 
Sbjct: 699  LVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTL 758

Query: 1901 GTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTG----TRTPVAHT-- 1954
             TS   S+ ST    TS    TS+      T T  T++     S G    T  PV+ T  
Sbjct: 759  LTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPV 818

Query: 1955 TSASSSRL-PTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFS 2013
            TS  +S L  TP  ++SP T S+  SS+      +   T+TY     P T++P      +
Sbjct: 819  TSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVA 878

Query: 2014 TSLVTPSTHTVIITTHTQMATSASIHSTPT---GTVPPPTT------------------L 2052
            TS ++ +  T  + T T +  S    S+PT   GT  P +T                  +
Sbjct: 879  TSAIS-TLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVV 937

Query: 2053 KATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLP 2112
             +   T +A P+  +T  T+ T ++ S  TA  + I +S+  P   ++   S+P++  L 
Sbjct: 938  SSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTST--PSEGTTPLTSTPVSHTLV 995

Query: 2113 HLSSA----TTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSA 2168
              S A    TTPV +   L++S   S   P+   + +P       TS+PS G S+     
Sbjct: 996  ANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMP-------TSTPSEG-STPLTRM 1047

Query: 2169 PVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLP-HTISSPFTLSALLP 2227
            PV +T ++S   S+LST P   S   +    +S +++T    ++P  T S   T    +P
Sbjct: 1048 PVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVP 1107

Query: 2228 ISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVS 2287
            +ST  V  + +S L S+T    S P TT++       SS  TT+  TS+ T  P+ G   
Sbjct: 1108 VSTRLVVSSEASTL-STTPVDTSIPVTTST-----EASSSPTTAEGTSIPTSPPSEG--- 1158

Query: 2288 LTSGVTGIPTSPVTNLTTRHPGPTLSPT---TRFLTSSLTAHGSTPASAPVSSLGTPTP 2343
             T+ +  +P S  T L       TLS T   ++   ++ T   S P +A V+S+ T TP
Sbjct: 1159 -TTPLASMPVS--TTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTP 1214



 Score =  278 bits (710), Expect = 6e-74
 Identities = 372/1316 (28%), Positives = 553/1316 (42%), Gaps = 163/1316 (12%)

Query: 1164 SQPQSVPGSNIEGCYNCS-QDEYFDHEEGVCVPCMPPTTPQPPTTP----QLPTT--GSR 1216
            S P S PG       N         + E   +   P  T  P TT       PTT  G+ 
Sbjct: 2681 SMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTS 2740

Query: 1217 PTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTT 1276
                 P  G++    +L ST P  SS  +  S T      A  TS   T S+     PTT
Sbjct: 2741 MRISTPSDGSTPLTSILVSTLPVASSEASTVSTT------AVDTSIPVTTSTEASSSPTT 2794

Query: 1277 A-VTPQATSGLPPTAT-LRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTP 1334
            A VT   TS    T+T L S     T   ++   T ST +P  TST  +T+    + PT 
Sbjct: 2795 AEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLST-TPVDTSTPVTTSTKASSSPTT 2853

Query: 1335 ATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTT 1394
            A     P    S    L  +    TT    + AST   TTP        T+TE + + TT
Sbjct: 2854 AEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLS-TTPVDTSIPVTTSTEGSSSPTT 2912

Query: 1395 TEYTTP--QTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYP-------TPSHPETTLPT 1445
             E T+    TP    +P T  S + ST PV  +     +T P       T S   ++ PT
Sbjct: 2913 AEGTSMPISTPSEVSTPLT--SILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPT 2970

Query: 1446 HVPPFSTSLVTP-STHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504
                 S  + TP    T +T         AS+ ++     P  T+   T ST  +   T 
Sbjct: 2971 TAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPT- 3029

Query: 1505 TTSGTSQAHSSFSTNKTP-TSLHSHTSSTHHPEVTPTSTTTITPN-PTSTRTRTPVAHTN 1562
            T  GT    S+ S   TP TS+   T+    PE +  STT +  N P  T T    + T 
Sbjct: 3030 TAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTP 3089

Query: 1563 SATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYP----TP--------SHPQT 1610
            +  +S P   ++  S P    P S+T P+T+++  T +T P    TP        S P T
Sbjct: 3090 AEGTSMPISTYSEGSTPLTGVPVSTT-PVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTT 3148

Query: 1611 TLPTHVPPFSTSL-VTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAP 1669
            +  T +P  + S   TP T+  ++      +  +++ + P  T  P TT     S+ TA 
Sbjct: 3149 SEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAE 3208

Query: 1670 TMTLTTSGTSQALSSLNTAKTS--------------TSLHSHTSSTHHAEATST-STTNI 1714
              ++ TS  S+ ++ L +   S              T + S+T  T   EA+S+  T   
Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEG 3268

Query: 1715 TPNPTST---GTPPMT----VTTSGTSQSRSSFST--AKTSTSLHSHTSSTHHPEV---- 1761
            T  PTST   G+ P+T     TT+  S   S+ ST  A TST + +++ ++  P +    
Sbjct: 3269 TSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGT 3328

Query: 1762 ---TSTSTTSITPNHTSTGTRTPVAHTTSATSSRLP----TPFTTHSPPTGTTPISSTGP 1814
               TST +   TP    + + TPV  + ++T S  P    TP TT S     +P ++ G 
Sbjct: 3329 SMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTT-STEASLSPTTAEGT 3387

Query: 1815 VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPT 1874
               TS  +  T P  S P +T P      +T   TP     ++ T T+ ++S +I     
Sbjct: 3388 SIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTI---AE 3444

Query: 1875 GTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTS 1934
            GT   PT+  + GST  +     TT   S   S+ ST    TS P  TSS   P  +  +
Sbjct: 3445 GT-SLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSS---PTNSSPT 3500

Query: 1935 TTNITPKHTSTG-------TRTPVAHT---TSASSSRLPTPFTTHSPPTGSSPFSSTGPM 1984
            T  +T   TST        T  PV+ T   +S +S+   TP  +++  T SS  SS+   
Sbjct: 3501 TAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSS--- 3557

Query: 1985 TATSFQTTTTYPTPSHPQTTLPTHV--PPFSTSLVTPSTHTVIITTHTQMATSASIHSTP 2042
             AT   TT    TPS   ++L T +    + TS    +  T  +   T + TS   +STP
Sbjct: 3558 PATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTP 3617

Query: 2043 TGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRP 2102
              T P   TL  +  +  + P+T+    T+    S    TAS+  + +S+  P  +S++ 
Sbjct: 3618 --TPPEVITLPMSTPSEVSTPLTIMPVSTTSVTIS-EAGTASTLPVDTST--PVITSTQV 3672

Query: 2103 PSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQ--TSSP-SV 2159
             SSP+T +       T P+ T ++ S+  +  P + + V+S   S+ S+P   TS+P + 
Sbjct: 3673 SSSPVTPE-----GTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTT 3727

Query: 2160 GTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPL-------FPSSPAASTTI-RAT 2211
             T +   SA + STT+S      +ST  TT  VS +P+        PS P+  T++   T
Sbjct: 3728 STEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTT 3787

Query: 2212 LPHTISSPFTL--SALLPIST--------VTVSPTPSSHLASSTIAFPSTP--------- 2252
                 SSP TL  +  +P+ST         TV  +P S ++ S  +  STP         
Sbjct: 3788 ASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLL 3847

Query: 2253 -RTTASTHTAPA----FSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRH 2307
              T A + + PA         T+ RST LTT + ++   +   G +   T P+   TT  
Sbjct: 3848 TSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFT 3907

Query: 2308 PG------PTLSPTTRFLTSSLTAHGSTPA------SAPV-SSLGTPTPTSPGVCS 2350
            P       PT+ P    ++ S+   GSTP       S PV SS     P + G  S
Sbjct: 3908 PSTDTASTPTI-PVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVS 3962



 Score =  266 bits (679), Expect = 2e-70
 Identities = 323/1120 (28%), Positives = 494/1120 (44%), Gaps = 161/1120 (14%)

Query: 1353 GTTATQTTGPRPTPASTTGP---------TTPQPG-QPTRPTATET-TQTRTTTEYTT-- 1399
            GTT+T    PR   + +T P         T+  PG   TR T TE+ T + +T++ TT  
Sbjct: 70   GTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLF 129

Query: 1400 PQTPHTTHSPPT-AGSPVPSTGP---VTATSFHATTTYPTPSHPETTLPTHVPPFSTSLV 1455
            P +   T SP T  G+ VP + P     +++    +T P PS    T  T+    ST L 
Sbjct: 130  PSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLT 189

Query: 1456 TPSTHTVITPTHAQMAT---SASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGT--- 1509
            T ST    +PT  +  T   S ++  +   T  P +T+K   S       TP    T   
Sbjct: 190  T-STQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVT 248

Query: 1510 --SQAHSSFSTNKTPTSLHSHTSSTHHP--------------EVTPTSTTTITPN-PTST 1552
              +QA SS +T + P+  +S  S    P              E +  STT    N P  T
Sbjct: 249  ISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVIT 308

Query: 1553 RTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKT-------TTTYPTP 1605
             T    + T +  +S P   +T  S P  S+P +ST P+  +   T       T+T  T 
Sbjct: 309  STEASSSPTTAEGTSIPTSTYTEGSTPLTSTP-ASTMPVATSEMSTLSITPVDTSTLVTT 367

Query: 1606 SHPQTTLPTHVPPFSTSLVTPSTHTVITP-THAQMAT--SASIHSMPTGTIP------PP 1656
            S   ++LPT     +TS++T +     TP T+  ++T   AS  +  T TIP        
Sbjct: 368  STEPSSLPTTAE--ATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVT 425

Query: 1657 TTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITP 1716
            T  +A+ S  TA   ++ TS  S+  + L +   ST+  + + +++ +     S T +T 
Sbjct: 426  TASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTT 485

Query: 1717 NPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTST 1776
            +  ++ +PP     S  + + S  ST  TS S+     ST     +  ST S TP  TST
Sbjct: 486  STEASSSPPTAEVNSMPTSTPSEGSTPLTSMSV-----STMPVASSEASTLSTTPVDTST 540

Query: 1777 GTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS----STGPVTATSFQTTTTYPTPSHP 1832
               T    ++S+T+    T   T +P  G+TP++    ST  V ++   TT+T P  S+ 
Sbjct: 541  PVTTSSEASSSSTTPE-GTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNT 599

Query: 1833 HTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTA 1892
              T  +   S ST+    S     +PT T      +I SM   T    ++  +T ST   
Sbjct: 600  FVTTSSEASSSSTTAEGTS-----MPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPV 654

Query: 1893 PPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT--PTSTTNITPKHTSTGTRTP 1950
               TP T  TS   +S ST    TS+P  T +     +T  P +TT +     ST + TP
Sbjct: 655  DSNTPVT--TSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTP 712

Query: 1951 V----AHTTSASSSRLPT-----PFTTHSPPTGSSPFS-----------------STGPM 1984
            V      TTS  +S  PT        T +P  GS+P +                 ST P+
Sbjct: 713  VDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPL 772

Query: 1985 TATSFQTTTTYPTPSHPQTTLPTHVP--------PFSTSL---VTPST-------HTVII 2026
              ++  TT+T  + S P TT  T +P        P  TS+   +TP T        T  +
Sbjct: 773  DTSTHITTSTEASCS-PTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPV 831

Query: 2027 TTHTQMATSASIHSTPT---GTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATA 2083
             +++ + TS  + S+PT   GT  P +T     +  T+ P++ T   TS   +  +T   
Sbjct: 832  DSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVD 891

Query: 2084 SSSFISS-----SSWLPQNSSSRPPSSP--ITTQLPHLSSATTPVSTTNQLSSSFSP-SP 2135
            +S+ +++     SS      +S P S+P   +T L  +  +TTPV ++   + S +P   
Sbjct: 892  TSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDT 951

Query: 2136 SAPSTVSSYVPSSHSSPQ-----TSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHP--- 2187
            S P T S+   SS ++ +     TS+PS GT +   S PV  T +++   S+LST P   
Sbjct: 952  STPVTTSTEATSSPTTAEGTSIPTSTPSEGT-TPLTSTPVSHTLVANSEASTLSTTPVDS 1010

Query: 2188 -TTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTI 2246
             T  + S     P   A  T++  + P   S+P T    +P+ST  V+ + +S L S+T 
Sbjct: 1011 NTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLT---RMPVSTTMVASSETSTL-STTP 1066

Query: 2247 AFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTR 2306
            A  STP TT S       SS STT+  TS+    PTS +   ++ +T +P S  T L   
Sbjct: 1067 ADTSTPVTTYS-----QASSSSTTADGTSM----PTSTYSEGSTPLTSVPVS--TRLVVS 1115

Query: 2307 HPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSP 2346
                TLS TT   TS      +  +S+P ++ GT  PTSP
Sbjct: 1116 SEASTLS-TTPVDTSIPVTTSTEASSSPTTAEGTSIPTSP 1154



 Score =  228 bits (582), Expect = 4e-59
 Identities = 278/1003 (27%), Positives = 431/1003 (42%), Gaps = 116/1003 (11%)

Query: 1198 PPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPT----QTP 1253
            P TT    T+       S PT   P  G +    +  S  P  SS  +  S T     TP
Sbjct: 3194 PVTTSTEATSSTTAEGTSIPTST-PSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP 3252

Query: 1254 LLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTA 1313
            L  +T  SS P  + G     T+  T   + G  P  ++  + T    T A++  +  + 
Sbjct: 3253 LTTSTEASSSPPTAEG-----TSMPTSTPSEGSTPLTSMPVSTT----TVASSETSTLST 3303

Query: 1314 SPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQE--LPGTTATQTTGPRPTPASTTG 1371
            +PA TST  +T     + P P   GTS  +P ST  E   P T  + +T P  +  ++T 
Sbjct: 3304 TPADTSTPVTTYSQASSSP-PIADGTS--MPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360

Query: 1372 PTTPQPGQPTRPTATETTQTRTTTEYTT-PQTPHTTHSPPTAGSPVPSTGPVTATSFHAT 1430
             TTP        T+TE + + TT E T+ P +  +  + P A  PV ST PV ++  +  
Sbjct: 3361 STTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPV-STTPVVSSEVNTL 3419

Query: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQ----MATSASNHSAPTGTIPP 1486
            +T P  S+              +LVT ST    +PT A+      ++ S  S P   +P 
Sbjct: 3420 STTPVDSN--------------TLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPL 3465

Query: 1487 PTTLKAT---GSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVT--PTS 1541
             TT  A+    +  T P  T T   TS   +S  T    TS+ + T+      +T  P S
Sbjct: 3466 STTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVS 3525

Query: 1542 TTTITPNPTSTRTRTP------VAHTNSATSSRPPPPFTT---HSPPTGSSPFSSTGPMT 1592
            TT +  +  ST + TP      V  ++ A+SS      TT    +P  GSS  S T  + 
Sbjct: 3526 TTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSS--SLTTMLL 3583

Query: 1593 ATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIT-PTHAQMATSASIHSMPTG 1651
            ++++ T++   TPS P     T V   + S  TP+   VIT P       S  +  MP  
Sbjct: 3584 SSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVS 3643

Query: 1652 TIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATS--T 1709
            T     T+   G+  T P  T T   TS  +SS       T++   T S      T+   
Sbjct: 3644 T--TSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPV 3701

Query: 1710 STTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSI 1769
            STT +T +  ST + P  VT++  + S  + S   +S +L S T S   P   ST  T+I
Sbjct: 3702 STTRVTSSEGSTLSTPSVVTSTPVTTSTEAIS---SSATLDSTTMSVSMPMEISTLGTTI 3758

Query: 1770 TPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYP-T 1828
                    + TPV     +++  +P+ +T+ S  T     +S G  + T+ + TTT P +
Sbjct: 3759 LV------STTPVTRFPESSTPSIPSVYTSMSMTT-----ASEGSSSPTTLEGTTTMPMS 3807

Query: 1829 PSHPHTTLPTHVPSFSTSLVTPS-THTVIIP---THTQMATSASIHSMPTGTIPPP-TTI 1883
             +   +TL T V     S+++PS   T+  P   T T + TS    S    +IP   TTI
Sbjct: 3808 TTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSF---SIPAEVTTI 3864

Query: 1884 KATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNI----- 1938
            + + ++  + P+T     T+  P+SF  A  +++ P  TS+T  P     ST  I     
Sbjct: 3865 RISITSERSTPLTTLLVSTT-LPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATT 3923

Query: 1939 ----------TPKHTSTGTRTPVAHTTS----ASSSRLPTPFTTHSPPTGSSPFSSTGPM 1984
                      TP  T     TPV  +T+    A++  + TP  T +     S  SS+   
Sbjct: 3924 ISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSS--- 3980

Query: 1985 TATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
            T TSF TT  + TP+   T  P      ST+  TP T +   TT     ++ S   T T 
Sbjct: 3981 TTTSFSTTKEFTTPA-MTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTS 4039

Query: 2045 TVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQ---NSSSR 2101
                 TT   T S+ ++ P T+T+     T     ++T  ++  SS++  P+     ++R
Sbjct: 4040 V----TTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTR 4095

Query: 2102 PPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSY 2144
               S  TT  P +++   P +TT  + S+ + +P+ P T + +
Sbjct: 4096 TKPSTRTTSFPTVTTTAVPTNTT--IKSNPTSTPTVPRTTTCF 4136



 Score =  223 bits (569), Expect = 1e-57
 Identities = 278/969 (28%), Positives = 409/969 (42%), Gaps = 138/969 (14%)

Query: 1467 HAQMATSASNHSAPTGT--IPPPTTLKATGSTHTAPPITPTTSG-TSQAHSSFSTNKTP- 1522
            H +  ++A+  +  T T  + P   L    S  T P +T   S  TS      ST  TP 
Sbjct: 58   HVRTGSAANTATGTTSTNVVEPRMYL----SCSTNPEMTSIESSVTSDTPGVSSTRMTPT 113

Query: 1523 ----TSLHSHTSSTHHPEVTPTSTTTITPN----PTSTRTRTPVAHTNSATSSRPPPPFT 1574
                TS  +  S+T  P  T  +++  TP     P ST +   ++ T +  S+ P P F 
Sbjct: 114  ESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFE 173

Query: 1575 TH---------SPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVT 1625
             +         S P  +S  +S+ P T  S    TT P  ++ + + P    P ST  V 
Sbjct: 174  AYTSLTYKVDMSTPLTTSTQASSSPTTPES----TTIPKSTNSEGSTPLTSMPASTMKVA 229

Query: 1626 PSTHTVITPTHAQMATSASI-----------------HSMPTGTIPPPT----------- 1657
             S    +  T  +++T  +I                 +S P+G   P T           
Sbjct: 230  SSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVS 289

Query: 1658 ----TLKATGSTHTAPTMTLTTSGTSQALSSLNTAKT------STSLHSHTSSTHHAEAT 1707
                TL  T +    P +T T + +S   +   +  T      ST L S  +ST     +
Sbjct: 290  SEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATS 349

Query: 1708 STSTTNITPNPTS----TGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTS 1763
              ST +ITP  TS    T T P ++ T+  + S  + + ++ ST L +   ST     + 
Sbjct: 350  EMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSE 409

Query: 1764 TSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS----STGPVTATS 1819
             STTS  P  + T   T    ++S T++   T   T +P  G+TP++    ST PV ++ 
Sbjct: 410  ASTTSTIPVDSKTFVTTASEASSSPTTAE-DTSIATSTPSEGSTPLTSMPVSTTPVASSE 468

Query: 1820 FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPP 1879
                +T P  S    T  T   S       P+     +PT T    S  + SM   T+P 
Sbjct: 469  ASNLSTTPVDSKTQVTTSTEASS-----SPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPV 523

Query: 1880 PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT--PTSTTN 1937
             ++  +T ST      TP T  TS   SS ST    TS+P  T S     +T  P ST  
Sbjct: 524  ASSEASTLSTTPVDTSTPVT--TSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRL 581

Query: 1938 ITPKHTSTGTRTPVAH----TTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTT 1993
            +     ST + TP       TTS+ +S   T     S PT  S +S  G  T TS   +T
Sbjct: 582  VVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPT--STYSERG-TTITSMSVST 638

Query: 1994 TYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITT---HTQMATSASIH-STPTGTVPPP 2049
            T    S   T   T  P  S + VT ST     +T    T M TS     STP  ++P  
Sbjct: 639  TLVASSEASTLSTT--PVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVN 696

Query: 2050 TTLKAT--GSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPI 2107
            TTL A+   ST +  P+  +T  T+ T +S S  TA  + + +S+  P   S+   S P+
Sbjct: 697  TTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTST--PSEGSTPLTSMPV 754

Query: 2108 TTQLPHLSSA----TTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSS 2163
            +  L   S A    TTP+ T+  +++S   S S  +T  + +P        S+PS G S 
Sbjct: 755  SKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMP-------ISTPSEG-SP 806

Query: 2164 SFVSAPVHSTTLSSGSHSSLSTHP--------TTASVSASPLFPSSPAASTTIRATLPHT 2215
               S PV  T ++S   S+LST P        T+  VS+SP    +PA  T++  +   T
Sbjct: 807  LLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSP----TPAEGTSMPTS---T 859

Query: 2216 ISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTS 2275
             S   T    +P+ST  V+ +  S L S+T    STP T ++        S  TTS  TS
Sbjct: 860  YSEGRTPLTSMPVSTTLVATSAISTL-STTPVDTSTPVTNST-----EARSSPTTSEGTS 913

Query: 2276 LTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPV 2335
            + T  P  G   LTS      T+PV +   R    T   T+  +T+S T   S+P +A  
Sbjct: 914  MPTSTPGEGSTPLTSMPDS--TTPVVSSEARTLSATPVDTSTPVTTS-TEATSSPTTAEG 970

Query: 2336 SSLGTPTPT 2344
            +S+ T TP+
Sbjct: 971  TSIPTSTPS 979



 Score =  217 bits (552), Expect = 1e-55
 Identities = 277/1008 (27%), Positives = 405/1008 (40%), Gaps = 152/1008 (15%)

Query: 1199 PTTPQPPTTP-QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPA 1257
            PTT +  + P   P+ GS P    P++         S+   +P    TP + T T    +
Sbjct: 3146 PTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVT-TSTEATSS 3204

Query: 1258 TLT--SSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS---- 1311
            T    +S PT++  E   P T+V    T      A++ ST    + T  TT   AS    
Sbjct: 3205 TTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPP 3264

Query: 1312 ----TASPATTSTAQSTTRTTMTLPTP--ATSGTSPTLPKSTNQELPGTTATQTTGPRPT 1365
                T+ P +T +  ST  T+M + T   A+S TS       +   P TT +Q +   P 
Sbjct: 3265 TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPI 3324

Query: 1366 PASTTGPT-------TPQPGQP--TRPTATETTQTRTTTEYTTPQTPHTTH-----SPPT 1411
               T+ PT       TP       T P  +    T +TT   T  TP TT      SP T
Sbjct: 3325 ADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDT-STPVTTSTEASLSPTT 3383

Query: 1412 A-GSPVPSTGPVTATSFHAT---TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTH 1467
            A G+ +P++ P   T+  A+   +T P  S    TL T  P  S +LVT ST    +PT 
Sbjct: 3384 AEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLST-TPVDSNTLVTTSTEASSSPTI 3442

Query: 1468 AQ----MATSASNHSAPTGTIPPPTTLKATGSTHT---APPITPTTSGTSQAHSSFSTNK 1520
            A+      ++ S  S P   +P  TT  A+    T    P  T T   TS   +S  T  
Sbjct: 3443 AEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTA 3502

Query: 1521 TPTSLHSHTSSTHHPEVT--PTSTTTITPNPTSTRTRTPV------AHTNSATSSRPPPP 1572
              TS+ + T+      +T  P STT +  +  ST + TPV        ++ A+SS     
Sbjct: 3503 EVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQ 3562

Query: 1573 FTT---HSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTH 1629
             TT    +P  GSS  S T  + ++++ T++   TPS P     T V   + S  TP+  
Sbjct: 3563 VTTMRMSTPSEGSS--SLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPP 3620

Query: 1630 TVIT-PTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTA 1688
             VIT P       S  +  MP  T     T+   G+  T P  T T   TS  +SS    
Sbjct: 3621 EVITLPMSTPSEVSTPLTIMPVSTTS--VTISEAGTASTLPVDTSTPVITSTQVSSSPVT 3678

Query: 1689 KTSTSLHSHTSSTHHAEATS--TSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKT- 1745
               T++   T S      T+   STT +T +  ST + P  VT++  + S  + S++ T 
Sbjct: 3679 PEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATL 3738

Query: 1746 -----------------STSLHSHTSSTHHPEVTSTSTTSITPNHTST------------ 1776
                             +T L S T  T  PE ++ S  S+  + + T            
Sbjct: 3739 DSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTL 3798

Query: 1777 -GTRTPVAHTTSATSSRL------------PTPFTTHSPPTGTTP--------------- 1808
             GT T    TTS  S+ L            P+  +T S P G T                
Sbjct: 3799 EGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIP 3858

Query: 1809 ---------ISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPT 1859
                     I+S      T+   +TT PT S P  ++ +  P  +++  TPST T   PT
Sbjct: 3859 AEVTTIRISITSERSTPLTTLLVSTTLPT-SFPGASIASTPPLDTSTTFTPSTDTASTPT 3917

Query: 1860 HTQMATSASIHSMPTGTIPPPTT-IKATGSTHTAPPMTPTTSGTSQSP----SSFSTAKT 1914
               +AT+ S+  +  G+ P  T  I +T  T +   + P T+G   +P    +  +T  T
Sbjct: 3918 -IPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPST 3976

Query: 1915 STSLPYHTSSTHHPEVTPTSTTNI------------TPKHTSTGTRTPVAHTTSASSSRL 1962
            S+S    + ST     TP  TT              TP+ TS G  T  +  ++ S+   
Sbjct: 3977 SSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHT 4036

Query: 1963 PTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTH 2022
             T  TT  P T SS   S+ P T TS     T+P P+H  T   T     S++ V P   
Sbjct: 4037 STSVTTR-PVTPSS--ESSRPSTITSHTIPPTFP-PAHSSTPPTTSA---SSTTVNPEAV 4089

Query: 2023 TVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSG 2070
            T + T       + S  +  T  VP  TT+K+  ++    P T T  G
Sbjct: 4090 TTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFG 4137



 Score =  203 bits (517), Expect = 1e-51
 Identities = 260/955 (27%), Positives = 402/955 (42%), Gaps = 127/955 (13%)

Query: 1451 STSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTS 1510
            +T+  T ST+ V      +M  S S +   T +I    T    G + T   +TPT S T+
Sbjct: 66   NTATGTTSTNVV----EPRMYLSCSTNPEMT-SIESSVTSDTPGVSSTR--MTPTESRTT 118

Query: 1511 QAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPP 1570
               +S ST   P+S    +S T     TP  T      P ST +   ++ T +  S+ P 
Sbjct: 119  SESTSDSTTLFPSSTEDTSSPT-----TPEGTDV----PMSTPSEESISSTMAFVSTAPL 169

Query: 1571 PPFTTH---------SPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFST 1621
            P F  +         S P  +S  +S+ P T  S    TT P  ++ + + P    P ST
Sbjct: 170  PSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPES----TTIPKSTNSEGSTPLTSMPAST 225

Query: 1622 SLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQA 1681
              V  S    +  T  +++T  +I +  + +   PTT +    +++AP      SG S  
Sbjct: 226  MKVASSEAITLLTTPVEISTPVTISAQASSS---PTTAEGPSLSNSAP------SGGSTP 276

Query: 1682 LSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFS 1741
            L+ +       S+    SS     +T+ + TNI P  TST       T  GTS   S+++
Sbjct: 277  LTRM-----PLSVMLVVSSEASTLSTTPAATNI-PVITSTEASSSPTTAEGTSIPTSTYT 330

Query: 1742 TAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTST----GTRTPVAHTTSATSSRLPTPF 1797
                ST L S  +ST     +  ST SITP  TST     T      TT+  +S L +  
Sbjct: 331  EG--STPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTL 388

Query: 1798 TTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTL-------PTHVPSFSTSLVTP 1850
            +  S P    P+S T  V ++   TT+T P  S    T        PT     S +  TP
Sbjct: 389  SEGSTPLTNMPVS-TILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTP 447

Query: 1851 S---THTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPS 1907
            S   T    +P  T    S+   ++ T  +   T +  +    ++PP     S  + +PS
Sbjct: 448  SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS 507

Query: 1908 SFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFT 1967
              ST  TS S+     ST     +  ST + TP  TST   T  +  +S+S++   T   
Sbjct: 508  EGSTPLTSMSV-----STMPVASSEASTLSTTPVDTSTPVTTS-SEASSSSTTPEGTSIP 561

Query: 1968 THSPPTGSSPFSSTGPMT--ATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI 2025
            T +P  GS+P ++    T    S + +TT  TP+   T + T     S+S     T ++ 
Sbjct: 562  TSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGT-SMP 620

Query: 2026 ITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASS 2085
             +T+++  T+ +  S  T  V       +  ST +  P+   T  T+ T ++ S+ TA  
Sbjct: 621  TSTYSERGTTITSMSVSTTLVA-----SSEASTLSTTPVDSNTPVTTSTEATSSSTTAEG 675

Query: 2086 SFISSSSWLPQNSSSRPPSSPITTQLPHLSSA----TTPVSTTNQLSSSFSPSPSAPSTV 2141
            + + +S++     S+   S P+ T L   S A    TTPV T+  +++S   S S+P+T 
Sbjct: 676  TSMPTSTYT--EGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS-SSPTTA 732

Query: 2142 SSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSS 2201
                    +S  TS+PS G S+   S PV  T L+S   S+LST P   S   +    +S
Sbjct: 733  DG------ASMPTSTPSEG-STPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEAS 785

Query: 2202 PAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLAS-STIAFPSTPRTTASTHT 2260
             + +TT   ++P  IS+P   S LL    V+++P  S   ++ ST    S    T ST  
Sbjct: 786  CSPTTTEGTSMP--ISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEV 843

Query: 2261 APAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLT 2320
                SS  T +  TS+ T   + G   LTS    +P S                TT   T
Sbjct: 844  ----SSSPTPAEGTSMPTSTYSEGRTPLTS----MPVS----------------TTLVAT 879

Query: 2321 SSLTAHGSTPASAPVSSLGTPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGA 2375
            S+++   +TP             TS  V +  E +   T     +  T T  EG+
Sbjct: 880  SAISTLSTTPVD-----------TSTPVTNSTEARSSPTTSEGTSMPTSTPGEGS 923



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 98/415 (23%), Positives = 171/415 (41%), Gaps = 49/415 (11%)

Query: 1985 TATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTG 2044
            +A +  T TT      P+  L     P  TS+ +  T      + T+M  + S   T + 
Sbjct: 63   SAANTATGTTSTNVVEPRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTES--RTTSE 120

Query: 2045 TVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPS 2104
            +    TTL  + +  T+ P T   +    +  S  + +++ +F+S++           PS
Sbjct: 121  STSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPL---------PS 171

Query: 2105 SPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSS 2164
                T L +    +TP++T+ Q SSS  P+    +T+     S  S+P TS P+    S+
Sbjct: 172  FEAYTSLTYKVDMSTPLTTSTQASSS--PTTPESTTIPKSTNSEGSTPLTSMPA----ST 225

Query: 2165 FVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSA 2224
               A   + TL +      +    +A  S+SP     P+ S +     P   S+P T   
Sbjct: 226  MKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSA----PSGGSTPLTR-- 279

Query: 2225 LLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSG 2284
             +P+S + V  + +S L+++  A      T     T+   SS  TT+  TS+ T   T G
Sbjct: 280  -MPLSVMLVVSSEASTLSTTPAA------TNIPVITSTEASSSPTTAEGTSIPTSTYTEG 332

Query: 2285 FVSLTS----------------GVTGIPTSPVTNLTTRHPG-PTLSPTTRFLTSSLTAHG 2327
               LTS                 +T + TS +   +T     PT +  T  LTS+L + G
Sbjct: 333  STPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTL-SEG 391

Query: 2328 STP-ASAPVSSLGTPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEGACISAAS 2381
            STP  + PVS++   +  +    ++    +        A+ + T  E   I+ ++
Sbjct: 392  STPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATST 446


>gi|239757282 PREDICTED: similar to Fc fragment of IgG binding protein
            [Homo sapiens]
          Length = 1403

 Score =  281 bits (719), Expect = 6e-75
 Identities = 309/1235 (25%), Positives = 442/1235 (35%), Gaps = 223/1235 (18%)

Query: 45   CSTWGAGHFSTFDHHVYDFSGTCNYIFAAT-----CKDAFPTFSV----QLRRGPDGSIS 95
            C  WG  H+ +FD   +DF GTCNY+ A T            F+V    + R  P  S  
Sbjct: 75   CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLGVSTQGLTPFTVTTKNENRGNPAVSYV 134

Query: 96   RIIV--ELGASVVTVSEAIISVKDIGVIS-LPYT-SNGLQITPFGQSVRLVAKQLELELE 151
            R++    LG ++    + I  V+  GV++ LP + ++G      G S  L+     L++ 
Sbjct: 135  RVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVS 194

Query: 152  VVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPG- 210
              W  +  + V +   Y G +CGLCGN D    N+ V   G  L P           PG 
Sbjct: 195  YDW--NWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGT-LAPSIPIWGGSWRAPGW 251

Query: 211  -EIC------TFQDIPSTHVRQAQHARICTQLLT-----LVAPECSVSKEPFVLSCQADV 258
              +C      +    P   + Q +    C  L              V  E F   C  DV
Sbjct: 252  DPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDV 311

Query: 259  AAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKT 318
                  G  +  C  L+ Y   C   G  +  WR+   C +  CP N  Y+ CG  C  +
Sbjct: 312  CMGG--GDHDILCKALASYVAACQAAGVVIEDWRAQVGCEI-TCPENSHYEVCGPPCPAS 368

Query: 319  CSNPQHS-----CSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQ-CPCVLHGAMYAPGEVT 372
            C +P        C   C  GC C  G VL+       CVP+   C C  +G  +  G   
Sbjct: 369  CPSPAPLTTPAVCEGPCVEGCQCDAGFVLSA----DRCVPLNNGCGCWANGTYHEAGSEF 424

Query: 373  IA---ACQTCRCTLG--RWVCTERPC--------------------PGHCSLEGGSFVTT 407
             A     Q CRC  G    VCT   C                       C   G     T
Sbjct: 425  WADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVT 484

Query: 408  FDARPYRFHGTCTYIL---LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV 464
             D   + F GTC Y+L      P L  +   + V ++   S + +   +V        + 
Sbjct: 485  LDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLT 544

Query: 465  ISQ--DEVVTNNGEAKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVG 522
            +S      +  +G    LP++  ++     +   + + T+ GL L        +  V   
Sbjct: 545  LSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAA 604

Query: 523  PQFRGQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRAGNCPAALERET----DPC 578
              +     GLCGN+N D  DD     G   G        W+ G      E  +     PC
Sbjct: 605  --YAASLCGLCGNYNQDPADDLKAVGGKPAG--------WQVGGAQGCGECVSKPCPSPC 654

Query: 579  SMSQLNKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGD 638
            +  Q         C ++  T      CH  V PA +++ C+  AC  +     +C A+  
Sbjct: 655  TPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVAT 714

Query: 639  YVHACSLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPV 698
            YV AC   G  L  WR   D C + C  ++ +     +C  +C SLS  A E   SA   
Sbjct: 715  YVAACQAAGAQLGEWRRP-DFCPLQCPAHSHYELCGDSCPVSCPSLS--APEGCESACR- 770

Query: 699  DGCNCPDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQ 758
            +GC C D  ++     CV   QC C+ +G  + L                G +  P    
Sbjct: 771  EGCVC-DAGFVLSGDTCVPVGQCGCLHDGRYYPL----------------GEVFYP---- 809

Query: 759  MFLASCQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPG--CVCAEGLYEN 816
                                   G  C   C+            C PG    C EG    
Sbjct: 810  -----------------------GPECERRCE------------CGPGGHVTCQEG---- 830

Query: 817  ADGQCVPPEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHV 876
                C P EEC  E  GV           C    C R              C   G  H 
Sbjct: 831  --AACGPHEECRLE-DGVQ---------ACHATGCGR--------------CLANGGIHY 864

Query: 877  ITFDGQRFVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLS 936
            IT DG+ +   G+C Y+LA  VC        F I+ E     N+     R +    G + 
Sbjct: 865  ITLDGRVYDLHGSCSYVLA-QVCHPKPGDEDFSIVLEK----NAAGDLQRLLVTVAGQVV 919

Query: 937  VVLADRNYTVTGEEPHVQLGVTPGALSLVVD---ISIPGRYNLTLIWNRHMTILIRIARA 993
             +   +  TV GE   V L V  G + +  +   + +     L L+++    +L+ I   
Sbjct: 920  SLAQGQQVTVDGEA--VALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSP 977

Query: 994  SQDPLCGLCGNFNGNMKDDFETRSRYVASSELELVNSWK---ESPLCGDVSFV--TDPCS 1048
             +  LCGLCGNFNGN  DDF   +   ASS      +W+    S  CG+         C 
Sbjct: 978  FRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCL 1037

Query: 1049 LNAFRRSWAERKCSVINSQ--TFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVA 1106
                    +   C  + +    FATC + +    Y+  CV D C     GD   LC ++A
Sbjct: 1038 AEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCA--QKGDKAFLCRSLA 1095

Query: 1107 AYAQACLDKGVCV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCPSQ 1165
            AY  AC   GV V  WRT +FCP++C  ++                    HY  C    Q
Sbjct: 1096 AYTAACQAAGVAVKPWRTDSFCPLHCPAHS--------------------HYSICTRTCQ 1135

Query: 1166 PQSVPGSNIEGC-----YNCSQDEYFDHEEGVCVP 1195
                  S + GC       C  D+ F   +GVC+P
Sbjct: 1136 GSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIP 1170



 Score =  261 bits (668), Expect = 5e-69
 Identities = 257/1054 (24%), Positives = 403/1054 (38%), Gaps = 195/1054 (18%)

Query: 44   QCSTWGAGHFSTFDHHVYDFSGTCNYIFAATCKD---AFPTFSVQLRRGPDGSIS----- 95
            +C  WG  H+ T D H +DF GTC Y+ +A C         F+V +     GS +     
Sbjct: 473  ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTR 532

Query: 96   RIIVELGASVVTVSEAIISVKDI-GV-ISLPYTSNGLQITPFGQSVRLVAKQLELELEVV 153
             + +++    +T+S        + GV ++LP+  + L       +  +V     L L   
Sbjct: 533  SVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSL--A 590

Query: 154  WGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEPHKFAALQKLDDPGEIC 213
            +  DS + + V   Y   +CGLCGN++    ++  +  GK        A       GE C
Sbjct: 591  FDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGA----QGCGE-C 645

Query: 214  TFQDIPSTHVRQAQHA----RICTQLLTLVAPECS----VSKEPFVLSCQADVAAAPQPG 265
              +  PS    + Q +      C  +     P       V    +   C  D  A    G
Sbjct: 646  VSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLD--ACQVQG 703

Query: 266  PQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSACVKTCSN--PQ 323
                 C  ++ Y   C   G  +  WR P  C + QCPA+  Y+ CG +C  +C +    
Sbjct: 704  HPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPL-QCPAHSHYELCGDSCPVSCPSLSAP 762

Query: 324  HSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVTI---------- 373
              C S+C  GC C  G VL+      TCVPV QC C+  G  Y  GEV            
Sbjct: 763  EGCESACREGCVCDAGFVLS----GDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCE 818

Query: 374  ------------AAC---QTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGT 418
                        AAC   + CR   G   C    C G C   GG    T D R Y  HG+
Sbjct: 819  CGPGGHVTCQEGAACGPHEECRLEDGVQACHATGC-GRCLANGGIHYITLDGRVYDLHGS 877

Query: 419  CTYILLQ--SPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIVISQDEVVTNNGE 476
            C+Y+L Q   P+ P D     V +K+     +  LV V        + ++Q + VT +GE
Sbjct: 878  CSYVLAQVCHPK-PGDEDFSIVLEKNAAGDLQRLLVTVA----GQVVSLAQGQQVTVDGE 932

Query: 477  AKWLPYKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNF 536
            A  LP     + V  +   ++ + T+ GL L+          +++   FRG+  GLCGNF
Sbjct: 933  AVALPVAVGRVRVTAE-GRNMVLQTTKGLRLLFDGDA--HLLMSIPSPFRGRLCGLCGNF 989

Query: 537  NGDTTDDFTTSMGIAEGTASLFVDSWRAGN-------------CPAALERETDPCSMSQL 583
            NG+ +DDF    G A  +   F  +WR                CP  L  ET P   ++ 
Sbjct: 990  NGNWSDDFVLPNGSAASSVETFGAAWRVPGSSKGCGEGCGPQGCPVCLAEETAPYESNEA 1049

Query: 584  NKVCAETHCSMLLRTGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHAC 643
                    C  L      F  C A ++P+ ++++CVY  C  +     +C +L  Y  AC
Sbjct: 1050 --------CGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAAC 1101

Query: 644  SLRGVLLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNC 703
               GV +  WR+    C + C  ++ +S  ++ C+ +C +LS   T C  +    +GC C
Sbjct: 1102 QAAGVAVKPWRTD-SFCPLHCPAHSHYSICTRTCQGSCAALSG-LTGC--TTRCFEGCEC 1157

Query: 704  PDGTYLNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLAS 763
             D   L+Q G C+    C C   G +++    S + +  +  C                 
Sbjct: 1158 DDRFLLSQ-GVCIPVQDCGCTHNG-RYLPVNSSLLTSDCSERC----------------- 1198

Query: 764  CQAPKTFKSCSQSSENKFGAACAPTCQMLATGVACVPTKCEPGCVCAEGLYENADGQCVP 823
                    SCS SS                 G+ C    C PG VC              
Sbjct: 1199 --------SCSSSS-----------------GLTCQAAGCPPGRVC-------------- 1219

Query: 824  PEECPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQR 883
                             E+  + R C  +RG             C L    ++ TFDG R
Sbjct: 1220 -----------------EVKAEARNCWATRG------------LCVLSVGANLTTFDGAR 1250

Query: 884  FVFDGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLADRN 943
                    Y L++   G+ ++ P ++++ E  IC        +    F  G+  +  ++ 
Sbjct: 1251 GATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKG 1310

Query: 944  YTVTG---EEPHVQLGVTPGALSLVVDISIPGRYNLTL-IW-NRHMTILIRIARASQDPL 998
              V G   + P  +L     ++S   D S+  R    + +W   +  + + ++      L
Sbjct: 1311 VWVNGLRVDLPAEKLASV--SVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKL 1368

Query: 999  CGLCGNFNGNMKDDFETRSRYVASSELELVNSWK 1032
            CG CGNF+G+  +D+        S E   +  W+
Sbjct: 1369 CGACGNFDGDQTNDWHD------SQEKPAMEKWR 1396



 Score =  187 bits (475), Expect = 1e-46
 Identities = 217/861 (25%), Positives = 316/861 (36%), Gaps = 158/861 (18%)

Query: 371  VTIAACQTCRCTLGRWVCTERPCPGHCSLEGGSFVTTFDARPYRFHGTCTYILLQSPQLP 430
            VT    +TC+   G+ VC        C L G     +FD R + F GTC Y+L  +  L 
Sbjct: 50   VTCRPQETCKEQGGQGVCLPN-YEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCLG 108

Query: 431  EDGALMAVYDKSGVSHSE----TSLVAVVYLSRQD-KIVISQDEV--VTNNGEAKWLPYK 483
                 +  +  +  + +      S V VV ++     I I +DE+  V  NG    LP  
Sbjct: 109  VSTQGLTPFTVTTKNENRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVS 168

Query: 484  TRN--ITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFRGQTRGLCGNFNGDTT 541
              +  I+V +  S  L +A  FGL++       ++  VT+   + G   GLCGN + +  
Sbjct: 169  VADGRISVAQGASKALLVA-DFGLQVSYDWN--WRVDVTLPSSYHGAVCGLCGNMDRNPN 225

Query: 542  DDFTTSMGIAEGTASLFVDSWRA------------GNCPAALERETDPCSMSQLNKVCAE 589
            +D     G    +  ++  SWRA            G+CP         C   +L +    
Sbjct: 226  NDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPT--------CPEDRLEQYEGP 277

Query: 590  THCSMLLR-TGTVFERCHATVNPAPFYKRCVYQACNYEETFPHICAALGDYVHACSLRGV 648
              C  L   TG  F  CHA V P  F+K CV   C        +C AL  YV AC   GV
Sbjct: 278  GFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDHDILCKALASYVAACQAAGV 337

Query: 649  LLWGWRSSVDNCTIPCTGNTTFSYNSQACERTCLSLSDRATECHHSAVPVDGCNCPDGTY 708
            ++  WR+ V  C I C  N+ +      C  +C S +   T        V+GC C  G  
Sbjct: 338  VIEDWRAQV-GCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFV 396

Query: 709  LNQKGECVRKAQCPCILEGYKFILAEQSTVINGITCHCINGRLSCPQRPQMFLASCQAPK 768
            L+                      A++   +N       NG              C A  
Sbjct: 397  LS----------------------ADRCVPLN-------NG------------CGCWANG 415

Query: 769  TFKSCSQSSENKFGAACAPTCQMLATG--VACVPTKCEPGCVCAEGLYENADGQCVPPEE 826
            T+      SE      C+  C+    G  + C P  C  G VC  GL  +    C P   
Sbjct: 416  TYHEA--GSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVC--GLLPSGQHGCQPVST 471

Query: 827  CPCEFSGVSYPGGAELHTDCRTCSCSRGRWACQQGTHCPSTCTLYGEGHVITFDGQRFVF 886
              C+                                        +G+ H +T DG RF F
Sbjct: 472  AECQ---------------------------------------AWGDPHYVTLDGHRFDF 492

Query: 887  DGNCEYILATDVCGVNDSQPTFKILTENVICGNSGVTCSRAIKIFLGGLSVVLA---DRN 943
             G CEY+L+    G       F +   N   G+  V+ +R++ + +   S+ L+    R 
Sbjct: 493  QGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRK 552

Query: 944  YTVTGEEPHV--QLGVTPGALSLVVDISIPGRYNLTLIWNRHMTILIRIARASQDPLCGL 1001
              V G    +  QL     A     D+ +     L+L ++    + +R+  A    LCGL
Sbjct: 553  LQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGL 612

Query: 1002 CGNFNGNMKDDFETRSRYVASSELELVNSWKESPLCGDV--SFVTDPCSLNAFRRSWAER 1059
            CGN+N +  DD +      A  ++           CG+        PC+           
Sbjct: 613  CGNYNQDPADDLKAVGGKPAGWQVGGAQG------CGECVSKPCPSPCTPEQQESFGGPD 666

Query: 1060 KCSVINSQ--TFATCHSKVYHLPYYEACVRDACGCDSGGDCECLCDAVAAYAQACLDKGV 1117
             C VI++     A CH  V    Y++ C+ DAC     G    LC AVA Y  AC   G 
Sbjct: 667  ACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQ--GHPGGLCPAVATYVAACQAAGA 724

Query: 1118 CV-DWRTPAFCPIYCGFYNTHTQDGHGEYQYTQEANCTWHYQPCLCP--SQPQSVPGSNI 1174
             + +WR P FCP+ C          H  Y+   + +C     P  CP  S P+    +  
Sbjct: 725  QLGEWRRPDFCPLQC--------PAHSHYELCGD-SC-----PVSCPSLSAPEGCESACR 770

Query: 1175 EGCYNCSQDEYFDHEEGVCVP 1195
            EGC  C  D  F      CVP
Sbjct: 771  EGCV-C--DAGFVLSGDTCVP 788



 Score =  170 bits (431), Expect = 1e-41
 Identities = 157/578 (27%), Positives = 248/578 (42%), Gaps = 64/578 (11%)

Query: 31   RLKDSPQT--APDKGQCSTWGAGHFSTFDHHVYDFSGTCNYIFAATC--KDAFPTFSVQL 86
            RL+D  Q   A   G+C   G  H+ T D  VYD  G+C+Y+ A  C  K     FS+ L
Sbjct: 840  RLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVL 899

Query: 87   RRGPDGSISRIIVELGASVVTVSEAIISVKDIGVISLPYTSNGLQITPFGQSVRLVAKQL 146
             +   G + R++V +   VV++++      D   ++LP     +++T  G+++ L   Q 
Sbjct: 900  EKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVL---QT 956

Query: 147  ELELEVVWGPDSHLMVLVERKYMGQMCGLCGNFDGKVTNEFVSEEGKFLEP-HKFAALQK 205
               L +++  D+HL++ +   + G++CGLCGNF+G  +++FV   G        F A  +
Sbjct: 957  TKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWR 1016

Query: 206  LDDP----GEICTFQDIP---STHVRQAQHARICTQLLTLVAP----ECSVSKEPFVLSC 254
            +       GE C  Q  P   +      +    C QL     P    +  +S   +   C
Sbjct: 1017 VPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQC 1076

Query: 255  QADVAAAPQPGPQNSSCATLSEYSRQCSMVGQPVRRWRSPGLCSVGQCPANQVYQECGSA 314
              D+ A  Q G +   C +L+ Y+  C   G  V+ WR+   C +  CPA+  Y  C   
Sbjct: 1077 VYDLCA--QKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPL-HCPAHSHYSICTRT 1133

Query: 315  CVKTCS--NPQHSCSSSCTFGCFCPEGTVLNDLSNNHTCVPVTQCPCVLHGAMYAPGEVT 372
            C  +C+  +    C++ C  GC C +  +L    +   C+PV  C C  H   Y P   +
Sbjct: 1134 CQGSCAALSGLTGCTTRCFEGCECDDRFLL----SQGVCIPVQDCGCT-HNGRYLPVNSS 1188

Query: 373  I----------------AACQTCRCTLGRWVC----TERPC---PGHCSLEGGSFVTTFD 409
            +                  CQ   C  GR VC      R C    G C L  G+ +TTFD
Sbjct: 1189 LLTSDCSERCSCSSSSGLTCQAAGCPPGR-VCEVKAEARNCWATRGLCVLSVGANLTTFD 1247

Query: 410  ARPYRFHGTCTYIL-LQSPQLPEDGALMAVYDKSGVSHSETSLVAVVYLSRQDKIV-ISQ 467
                       Y L  + P L        V  +  + H +T  V  V++  QD +V ++ 
Sbjct: 1248 GARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTP 1307

Query: 468  DEVVTNNGEAKWLP-YKTRNITVFRQTSTHLQMATSFGLELVVQLRPIFQAYVTVGPQFR 526
            ++ V  NG    LP  K  +++V R     L +    G++  V L    +  V V     
Sbjct: 1308 NKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQ--VWLGANGKVAVIVSNDHA 1365

Query: 527  GQTRGLCGNFNGDTTDDFTTSMGIAEGTASLFVDSWRA 564
            G+  G CGNF+GD T+D+  S    E  A   ++ WRA
Sbjct: 1366 GKLCGACGNFDGDQTNDWHDSQ---EKPA---MEKWRA 1397


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  281 bits (719), Expect = 6e-75
 Identities = 362/1273 (28%), Positives = 546/1273 (42%), Gaps = 180/1273 (14%)

Query: 1194 VPCMPPTTPQPPTTPQLPTTGSRP----TQVWPMTGTSTTIGLLSSTGPS-PSSNHTPAS 1248
            +  +P +T  P  +    T  S P    T + P + TS  +G  S+T  S P S H+  S
Sbjct: 2311 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 2370

Query: 1249 P--TQTPLLP---ATLTSSKP--TASSGEPPRPTTAVTPQ--ATSGLPPTATLRSTATKP 1299
            P  T TP L     T+ SS P  T ++  P  PTT+V  +   T    P +T  +  T+ 
Sbjct: 2371 PASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTED 2430

Query: 1300 TVTQATTR-ATASTASPATTSTAQSTTRTTMTLPTPATS--------GTSPTLPKSTNQE 1350
            + T   T  +TA   SPA+T T    T TT  L   +T+        GT+ +  +ST   
Sbjct: 2431 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSG 2490

Query: 1351 LPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPP 1410
            L G    ++T  R +P+ST   TT  PG PT P+ +E    ++TT YT+P++P  T SP 
Sbjct: 2491 LVG----ESTPSRLSPSSTE--TTTLPGSPTTPSLSE----KSTTFYTSPRSPDATLSPA 2540

Query: 1411 TAGSPVPST---------GPVTATSFHATTTYPTPSHPETTLPTHVPPFST-SLVTPSTH 1460
            T  S   S          G    T+F  +TT P  S   TT  +H  P ST + + P++ 
Sbjct: 2541 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTT--SHSSPGSTDTTLLPAST 2598

Query: 1461 TVITPTHAQMATSASNHSAPTGTIPPPTTLKATGST----HTAPPITPTTSGTSQAHSSF 1516
            T   P+     + +S  S  T   P  TT  + G      H++P  T TT       SS 
Sbjct: 2599 TTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSS- 2657

Query: 1517 STNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTH 1576
               +  T +HS T S     ++P S+T+      ST  +T  A T++     P PP T  
Sbjct: 2658 GIVEASTRVHSSTGSPR-TTLSPASSTSPGLQGESTTFQTHPASTHTT----PSPPSTAT 2712

Query: 1577 SPPTGSSPFS-STGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPT 1635
            +P   S+ +  S G    T F  ++T  T  H + +   H  P ++     S H+  +  
Sbjct: 2713 APVEESTTYHRSPGSTPTTHFPASST--TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR 2770

Query: 1636 HAQMATSASIHSMPTGTIPPPTT---LKATGSTHTAPTMTLTTSGTSQALSSLNTAKTST 1692
                 +  S  S    T+P  TT   L    +T  +   + TT+ +  +++SL   + ST
Sbjct: 2771 GESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST 2830

Query: 1693 SLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSH 1752
            +  S   STH   + +++TT   P  +   T   TV +S    + ++     T+TS+   
Sbjct: 2831 TSRSQPGSTHSTVSPASTTT---PGLSEEST---TVYSSSPGSTETTVFPRSTTTSVRGE 2884

Query: 1753 TSSTHHPEVTSTSTTSITPNHTSTGTR---TPVAHTTSATSSRLPTPFTT----HSPPTG 1805
              +T H    ST TT  T + T++G     T    + ++T + LP   TT        T 
Sbjct: 2885 EPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTF 2944

Query: 1806 TTPISSTGPVTATSFQTTT-----TYPTPSHPHTTLPTHVPSFST--SLVTPSTHTVIIP 1858
             +   STG   + +  TT+     + P+   P +T  T +P   T  SL   ST     P
Sbjct: 2945 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 3004

Query: 1859 THTQMATSASIHSMPTGTIPPPTTIKATGSTH-TAPPMTPTTSGTSQSPSSFSTAKTSTS 1917
                   S +  +    +    T+    GSTH TA P + TTSG SQ P++  +++ ST 
Sbjct: 3005 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTE 3064

Query: 1918 LPYHTSSTHHPEVTPTSTT-NITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSS 1976
                  ST    +   STT + +P  T T        T+    +  PT  +T S  T  +
Sbjct: 3065 ATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLT 3124

Query: 1977 PFSSTG---PMTATSFQT--TTTYPTPSHPQTT-LPTHVPP--FSTSLVTPSTH-TVIIT 2027
            P SST       +T+FQ+  +++  TPS P TT  P  V     S    TP+TH +   T
Sbjct: 3125 PASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASST 3184

Query: 2028 THTQMATSASIHSTP--TGTV-------------PPPTTLKATGSTH-TAPPMTVTTSGT 2071
            T  +   S ++HS+P  TGT               P T+  ++GST  TA P + TT+G 
Sbjct: 3185 TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGL 3244

Query: 2072 SQTHSSF-----------STATASSSFISSSSWLPQNSSSRPPSS-----PITTQLPHLS 2115
            S+  ++F           S A+ +SS +S  S     S SRP S+     P +T +P +S
Sbjct: 3245 SEKSTTFYSSPRSPDTTLSPASTTSSGVSEES---TTSHSRPGSTHTTAFPGSTTMPGVS 3301

Query: 2116 -SATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSP----QTSSPSVGTSSSFV--SA 2168
              +T   S+     ++ SP  +  S++     + HS P     T  P   T+S  +  S 
Sbjct: 3302 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEAST 3361

Query: 2169 PVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPI 2228
            PVHS+T     H++LS   +T     S  F S P +  T       T + P T SA + +
Sbjct: 3362 PVHSST--GSPHTTLSPAGSTTRQGESTTFQSWPNSKDT-------TPAPPTTTSAFVEL 3412

Query: 2229 STV---TVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF 2285
            ST    + S TP++H ++S+              T    S +STT  S+ + T    S  
Sbjct: 3413 STTSHGSPSSTPTTHFSASS--------------TTLGRSEESTTVHSSPVATATTPSPA 3458

Query: 2286 VSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTS---------SLTAHGSTP---ASA 2333
             S TSG+       V   TT H  P  + T  F  S         S T+H ST    +SA
Sbjct: 3459 RSTTSGL-------VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 3511

Query: 2334 P-VSSLGTPTPTS 2345
            P  +S     PTS
Sbjct: 3512 PSTTSALVEEPTS 3524



 Score =  280 bits (715), Expect = 2e-74
 Identities = 389/1361 (28%), Positives = 563/1361 (41%), Gaps = 247/1361 (18%)

Query: 1194 VPCMPPTTPQPPTTPQLPTTGSRP----TQVWPMTGTSTTIGLLSSTGPS-PSSNHTPAS 1248
            +  +P +T  P  +    T  S P    T + P + TS  +G  S+T  S P S H+  S
Sbjct: 2785 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 2844

Query: 1249 PTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATS----GLPPT-------ATLRSTAT 1297
            P  T      L+    T  S  P    T V P++T+    G  PT       +T  +  T
Sbjct: 2845 PASTTT--PGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFT 2902

Query: 1298 KPTVTQATTR-ATASTASPATTSTAQSTTRTTMTLPTPATS--------GTSPTLPKSTN 1348
            + + T   T  +TA   SPA+T T    T TT  L   +T+        GT+ +  +ST 
Sbjct: 2903 EDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTT 2962

Query: 1349 QELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHS 1408
              L G    ++T  R +P+ST   TT  PG PT P+ +E    ++TT YT+P++P  T S
Sbjct: 2963 SGLVG----ESTPSRLSPSSTE--TTTLPGSPTTPSLSE----KSTTFYTSPRSPDATLS 3012

Query: 1409 PPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHA 1468
            P T  S   S    T+ S   +T         TT      P ++     ST   ++P   
Sbjct: 3013 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGST 3072

Query: 1469 QMAT----SASNHSAPTGT----IPPPT-----------TLKATGSTHTA-PPITPTTSG 1508
              ++    S + HS+P  T    +P  T           T  +TGS HT   P + T++G
Sbjct: 3073 TASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAG 3132

Query: 1509 TSQAHSSF-----STNKTP-----TSLHSHTSSTHH--PEVTPT-----STTTITPNPTS 1551
              +  ++F     S++ TP     T+     S+T+H  P  TPT     S+TT+  +  S
Sbjct: 3133 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 3192

Query: 1552 TR-------TRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTAT---SFKTTTT 1601
            T        T T +  T SATS     P TT    +GS+  ++    T T   S K+TT 
Sbjct: 3193 TTVHSSPGATGTALFPTRSATSVLVGEP-TTSPISSGSTETTALPGSTTTAGLSEKSTTF 3251

Query: 1602 YPTPSHPQTTLPTHVPPFS-------TSLVTP-STHTVITPTHAQMA----TSASIHSMP 1649
            Y +P  P TTL       S       TS   P STHT   P    M      S + HS P
Sbjct: 3252 YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSP 3311

Query: 1650 TGT----IPPPTTLKATG----STHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSST 1701
              T     P  TT  + G    + H+ P  T TT       +S    + ST +HS T S 
Sbjct: 3312 GSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTAS-GLLEASTPVHSSTGSP 3370

Query: 1702 HHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEV 1761
            H   + + STT    + T    P    TT     + S+F   + ST+ H   SST     
Sbjct: 3371 HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF--VELSTTSHGSPSSTPTTHF 3428

Query: 1762 TSTSTTSITPNHTSTGTRTPVAHTT------SATSSRLPTPFTTHSPP--TGTTPISSTG 1813
            +++STT      ++T   +PVA  T      S TS  +    T HS P  T T     + 
Sbjct: 3429 SASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESD 3488

Query: 1814 PVTATSFQTTTTYPTPSH----------------------PHTTLPTHVPSFST------ 1845
              +    ++TT++ + +H                      P +T  TH P  ST      
Sbjct: 3489 TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 3548

Query: 1846 -------------SLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTA 1892
                         ++V P+  T  +       +  S  SM T  +P  TT        T 
Sbjct: 3549 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT 3608

Query: 1893 PPMTPTTSGTSQSPSSFST------AKTSTSLPYHTSSTHHPE--VTPTSTTNITPKHTS 1944
               +P +  T+ SP+S ++      + TS S P  T +T  P+   TP  + + T  H+S
Sbjct: 3609 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 3668

Query: 1945 TG----TRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSF--QTTTTYPTP 1998
             G    T  P + TTS SS       T+HS    +    S G  TA SF  ++TT + +P
Sbjct: 3669 PGSTDTTLLPASTTTSGSSQE---STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSP 3725

Query: 1999 SHPQTTL-------------------------PTHVPPFSTSLVTPSTHTVIITTHTQMA 2033
                TTL                          T  P  STS       T   T      
Sbjct: 3726 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 3785

Query: 2034 TSASIHSTPTGTVPPPTTL-KATGSTHTAP-PMTVTTSGTSQTHSSF-----STATASSS 2086
            T+ S  ST T  V   TT  ++ GST T   P + TTSG S+  + F     ++ T  SS
Sbjct: 3786 TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 3845

Query: 2087 FISSSSWLPQNSSSR--PPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSY 2144
              S++S   ++++SR  P S+ ITT LP   S TTP    ++ S++F  SP +P+T  S 
Sbjct: 3846 AHSTTSGRGESTTSRISPGSTEITT-LP--GSTTTP--GLSEASTTFYSSPRSPTTTLS- 3899

Query: 2145 VPSSHSS------PQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLF 2198
             P+S +S        TS    G++ S VS    STT    S  S + + ++   + + +F
Sbjct: 3900 -PASMTSLGVGEESTTSRSQPGSTHSTVSPA--STTTPGLSEESTTVYSSSPGSTETTVF 3956

Query: 2199 PSSPAASTTIRATLPHTISSPFTLSALLPISTVT---VSPTPSSHLASSTIAFPSTPRTT 2255
            P S   +T++R   P T  S        P ST T      + +S L   + AFP +P +T
Sbjct: 3957 PRS--TTTSVRREEPTTFHS-------RPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 4007

Query: 2256 ----ASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPT----SPVTNLTTRH 2307
                 +T T      +STT  S+S +T    S   S TSG+ G  T    SP +  TT  
Sbjct: 4008 QTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTL 4067

Query: 2308 PGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGV 2348
            PG   SPTT  L+   T   ++P S P ++L   T TS GV
Sbjct: 4068 PG---SPTTPSLSEKSTTFYTSPRS-PDATLSPATTTSSGV 4104



 Score =  276 bits (705), Expect = 2e-73
 Identities = 361/1267 (28%), Positives = 537/1267 (42%), Gaps = 180/1267 (14%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSST-GPSPSSNHTPASP--TQ 1251
            P    TTP PP T   P   S      P +  +T     S+T G S  S    +SP  T 
Sbjct: 3144 PSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 3203

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            T L P   T S  +   GEP     +     T+ LP + T    + K T   ++ R+  +
Sbjct: 3204 TALFP---TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 3260

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGT-----SPTLP-----KSTNQELPGTTATQTTG 1361
            T SPA+T+++  +  +T +   P ++ T     S T+P      + +   PG+T T T  
Sbjct: 3261 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT-TLS 3319

Query: 1362 PRPTPASTTGP--TTPQPGQPTRPTATETTQTRTTT------EYTTPQTPHTTHSPPTAG 1413
            P  T AS+ GP  TT   G    P +TETT     T      E +TP    +T SP T  
Sbjct: 3320 PGSTTASSLGPESTTFHSG----PGSTETTLLPDNTTASGLLEASTP-VHSSTGSPHTTL 3374

Query: 1414 SPVPST---GPVTATSFHATTTYPTPSHPETT-------LPTHVPPFSTSLVTPSTH-TV 1462
            SP  ST   G  T       +   TP+ P TT         +H  P ST    P+TH + 
Sbjct: 3375 SPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSST----PTTHFSA 3430

Query: 1463 ITPTHAQMATSASNHSAP--TGTIPPPTTLKATGSTHTAPPITPTTSGTSQAH---SSFS 1517
             + T  +   S + HS+P  T T P P     +G    +     +   T   H   S  +
Sbjct: 3431 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTT 3490

Query: 1518 TNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHS 1577
            + +   S  SH+S+TH     P++T+ +   PTS               S P    TTH 
Sbjct: 3491 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYH-------------SSPGSTATTHF 3537

Query: 1578 PPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHA 1637
            P + +           TS ++  +  + S    T    +P  ST+ V     T    +  
Sbjct: 3538 PDSST-----------TSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSG 3586

Query: 1638 QMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSH 1697
             M T+A    +P  T  P  + K+T + H++P    TT   +   SS   ++ ST+ HS 
Sbjct: 3587 SMETTA----LPGSTTTPGLSEKST-TFHSSPRSPATTLSPASTTSS-GVSEESTTSHSR 3640

Query: 1698 TSSTHHA---EATST-------STTNITPNPTSTGTPPMTVTTSGTSQ----SRSSFSTA 1743
              STH     ++T+T       +T++ +P  T T   P + TTSG+SQ    S SS  + 
Sbjct: 3641 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGST 3700

Query: 1744 KTSTSLHSHT-------SSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTP 1796
             T+ S  S T       S+T H    ST TT    + TS+G         S+T S    P
Sbjct: 3701 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS----P 3756

Query: 1797 FTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHT-TLPTHVPS--FSTSLVTPSTH 1853
             TT SP + T+P    G  TA      +T+ TPS P T T P    +    +   TP+TH
Sbjct: 3757 RTTLSPASSTSP-GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH 3815

Query: 1854 TVIIPTHTQMATSASI-HSMP--TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFS 1910
                 T +  +  ++I HS P  +GT P         S H+      TTSG  +S +S  
Sbjct: 3816 FPASSTTSGHSEKSTIFHSSPDASGTTP--------SSAHS------TTSGRGESTTS-R 3860

Query: 1911 TAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTT----SASSSRLPTPF 1966
             +  ST +     ST  P ++  STT  +   + T T +P + T+      S++    P 
Sbjct: 3861 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 3920

Query: 1967 TTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVT---PST-H 2022
            +THS     SP S+T P    S ++TT Y   S P +T  T  P  +T+ V    P+T H
Sbjct: 3921 STHSTV---SPASTTTP--GLSEESTTVYS--SSPGSTETTVFPRSTTTSVRREEPTTFH 3973

Query: 2023 TVIITTHTQMATSASIHSTPTGTVPPPTTLKAT-GSTHTAPPMTVTTSGTSQTHSSF--- 2078
            +   +THT + T     ST +G     T    +  ST T  P T+TT+   +  ++F   
Sbjct: 3974 SRPASTHTTLFTE---DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS 4030

Query: 2079 --STATASSSFISSSSWLPQNS--SSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPS 2134
              ST T  S   S++S L   S  S   PSS  TT LP   S TTP  + ++ S++F  S
Sbjct: 4031 SGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLP--GSPTTP--SLSEKSTTFYTS 4086

Query: 2135 PSAPSTVSSYVPSSHS--SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASV 2192
            P +P    S   ++ S  S ++S+      S+  +A   STT S  S    ++H +  S 
Sbjct: 4087 PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGST 4146

Query: 2193 SASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVT---VSPTPSSHLASSTIAFP 2249
             A+ L P S  AS+  + +     S   T + LLP  T+T   V  +  +H ++ ++   
Sbjct: 4147 EAT-LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 4205

Query: 2250 STPRTTASTH------TAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVT-- 2301
             TP ++ ST       T  ++ S S T+ S   TT VP     +  S  +  PT+  +  
Sbjct: 4206 LTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSAS 4265

Query: 2302 --------NLTTRHPGPTLSPTTRFLTSSLTAH-GSTPASAPVSSLGTPTPTSPGVCSVR 2352
                      TT H  P  + T  F T S T+     P ++P+SS  T T   PG  +  
Sbjct: 4266 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTA 4325

Query: 2353 EQQEEIT 2359
               E+ T
Sbjct: 4326 GLSEKST 4332



 Score =  274 bits (701), Expect = 7e-73
 Identities = 361/1263 (28%), Positives = 529/1263 (41%), Gaps = 155/1263 (12%)

Query: 1212 TTGSRPTQVWPMTGTSTTIGL------LSSTGPSPSSNHTPASPTQTPLLPATLTSSKPT 1265
            ++GS  T   P  G++TT GL        S+  SP++  +PAS T + +   + TS    
Sbjct: 2027 SSGSMETTALP--GSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRP 2084

Query: 1266 ASSGEPPRPTTAVTP-----QATSGLPPTATLRSTATKPTVTQATTR-ATASTASPATTS 1319
             S+     P +  TP       TS   P +T  +     T T   ++ +T S +SP +T 
Sbjct: 2085 GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTD 2144

Query: 1320 TAQSTTRTTMTLPTPATSGTSPTLPKSTNQEL--PGTTATQTTGPRPTPASTTGP--TTP 1375
            TA S   TT  L     S T  + P ST+  L    TT++          S+TG   TT 
Sbjct: 2145 TALSPGSTT-ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2203

Query: 1376 QPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPP-TAGSPVP-------STGPVTATSF 1427
             P   T P      Q  +T   T P + HTT SPP TA +PV        S G    T F
Sbjct: 2204 SPASSTSPGL----QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHF 2259

Query: 1428 HATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPP 1487
             A++T  T  H E +   H  P ++     S H+  +       +  S  S    T+P  
Sbjct: 2260 PASST--TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 2317

Query: 1488 TT---LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTT 1544
            TT   L    +T  + P +PTT+ +  + +S    +  T+  S   STH   V+P STTT
Sbjct: 2318 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST-VSPASTTT 2376

Query: 1545 ITPNPTSTR--------TRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSF 1596
               +  ST         T T V      TS R   P T HS P  +     T   T +  
Sbjct: 2377 PGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGL 2436

Query: 1597 -KTTTTYP-TPSHPQTTLPTHVPPF-----STSLVTPSTHTVITPTHAQMATSASI-HSM 1648
             + +T +P +P+  QT LP  +        ST+  + S  T  T + A+  TS  +  S 
Sbjct: 2437 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGEST 2496

Query: 1649 PTGTIPPPTTLKATGSTHTAPTMT--LTTSGTSQAL--SSLNTAKTSTSLHSHTSSTHHA 1704
            P+   P  T       + T P+++   TT  TS     ++L+ A T++S  S  SST H+
Sbjct: 2497 PSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHS 2556

Query: 1705 EATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFST----AKTSTSLHSHTSSTHHPE 1760
            +  ST TT     P ST TP ++  ++ +  S  S  T    A T+TS  S  S+T H  
Sbjct: 2557 QPGSTHTTAF---PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 2613

Query: 1761 VTSTSTTSITPNHT---STGTRTPVAHTTSATSSRLPTPFTTHSP---PTGTTPISSTGP 1814
              ST T +++P  T   S G  +   H++  ++     P +T S       T   SSTG 
Sbjct: 2614 PGSTDT-ALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS 2672

Query: 1815 VTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPT 1874
               T    ++T P      TT  TH  S  T+   PST T  +   T    S    S PT
Sbjct: 2673 PRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG--STPT 2730

Query: 1875 GTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT-----------STSLPYHTS 1923
               P  +T        T    +P  SGT+ S +  +T+             ST +     
Sbjct: 2731 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 2790

Query: 1924 STHHPEVTPTSTTNITPKHTSTGTRTPVAHTT----SASSSRLPTPFTTHSPPTGSSPFS 1979
            ST  P ++  STT  +   + T T +P + T+      S++    P +THS     SP S
Sbjct: 2791 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTV---SPAS 2847

Query: 1980 STGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVT---PST-HTVIITTHTQMATS 2035
            +T P    S ++TT Y   S P +T  T  P  +T+ V    P+T H+   +THT + T 
Sbjct: 2848 TTTP--GLSEESTTVYS--SSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTE 2903

Query: 2036 ASIHSTPTGTVPPPTTLKAT-GSTHTAPPMTVTTSGTSQTHSSF-----STATASSSFIS 2089
                ST +G     T    +  ST T  P T+TT+   +  ++F     ST T  S   S
Sbjct: 2904 ---DSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARS 2960

Query: 2090 SSSWLPQNS--SSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPS 2147
            ++S L   S  S   PSS  TT LP   S TTP  + ++ S++F  SP +P    S   +
Sbjct: 2961 TTSGLVGESTPSRLSPSSTETTTLP--GSPTTP--SLSEKSTTFYTSPRSPDATLSPATT 3016

Query: 2148 SHS--SPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAAS 2205
            + S  S ++S+      S+  +A   STT S  S    ++H +  S  A+ L P S  AS
Sbjct: 3017 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEAT-LSPGSTTAS 3075

Query: 2206 TTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFS 2265
            +  + +     S   T + LLP  T+T     +S    S+     T  T AS+ T+    
Sbjct: 3076 SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS-TSAGLQ 3134

Query: 2266 SQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLT- 2324
             +STT +S       P+S     T    G   +PV   TT H  P+ +PTT F  SS T 
Sbjct: 3135 EESTTFQSW------PSSS--DTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL 3186

Query: 2325 -----------AHGST-----------------PASAPVSSLGTPTPTSPGVCSVREQQE 2356
                       + G+T                 P ++P+SS  T T   PG  +     E
Sbjct: 3187 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 3246

Query: 2357 EIT 2359
            + T
Sbjct: 3247 KST 3249



 Score =  274 bits (700), Expect = 9e-73
 Identities = 359/1274 (28%), Positives = 538/1274 (42%), Gaps = 195/1274 (15%)

Query: 1189 EEGVCVPCMPPTT----PQPPTTPQL--------PTTGSRPTQVWPMTGTSTTIGLLSST 1236
            EE    P  P +T    P   TT  L         ++GS  T++ P    STT GL+  +
Sbjct: 1355 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSP--ARSTTSGLVGES 1412

Query: 1237 GPS---PSSNHT---PASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTA 1290
             PS   PSS  T   P SPT TP L     S K T     P  P   ++P  T+    + 
Sbjct: 1413 TPSRLSPSSTETTTLPGSPT-TPSL-----SEKSTTFYTSPRSPDATLSPATTTSSGVSE 1466

Query: 1291 TLRSTATKPTVTQATTRATASTAS-----PATTSTAQSTTRTTMTLPTPATSGTSPTLPK 1345
               ++ ++P  T  T    ++T S     P T+ ++Q +T    TL   +T+ +S     
Sbjct: 1467 ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEA--TLSPGSTTASSLGQQS 1524

Query: 1346 STNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHT 1405
            +T    PG T T      P    T+G         +   +  TT T  ++     Q   T
Sbjct: 1525 TTFHSSPGDTETTLL---PDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEEST 1581

Query: 1406 T-HSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVIT 1464
            T  S P++    PS    TA     +TTY   S P +T  TH    ST+L      T + 
Sbjct: 1582 TFQSWPSSSDTTPSPPGTTAAPVEVSTTY--HSRPSSTPTTHFSASSTTLGRSEESTTVH 1639

Query: 1465 PTHAQMATSA-SNHSAPTGTIPPPTTLK-ATGSTH-TAPPITPTTSGTSQAHSSF-STNK 1520
             +     T+     SA +  +  PTT   ++GST  TA P + TT+G S+  ++F S+ +
Sbjct: 1640 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 1699

Query: 1521 TPTSLHSHTSSTHHPEVTPTSTTTITPNPTST------RTRTPVAHTNSATSSRPPPPFT 1574
            +P +  S  S+T       ++T+   P  T T       T   V+  ++A+ S P    T
Sbjct: 1700 SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT 1759

Query: 1575 THSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITP 1634
            T SP  GS+  SS GP      ++TT + +P   +TTL   +P  +T+            
Sbjct: 1760 TLSP--GSTTASSLGP------ESTTFHSSPGSTETTL---LPDNTTA------------ 1796

Query: 1635 THAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSL 1694
                +  S  +HS    T  P TTL   GST T    + T      +  ++    T+TS 
Sbjct: 1797 -SGLLEASTPVHS---STGSPHTTLSPAGST-TRQGESTTFQSWPSSKDTMPAPPTTTSA 1851

Query: 1695 HSHTSSTHHAEATSTSTTNITPNPTSTG----------TPPMTVTTSGTSQSRSSFSTAK 1744
                S+T H   +ST TT+ + + T+ G          +P  T TT   ++S +S    +
Sbjct: 1852 FVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS-GLVE 1910

Query: 1745 TSTSLHSHTSST---HHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHS 1801
             ST+ HS   ST   H PE ++ S  S     + + T   ++   S TS+ +  P + HS
Sbjct: 1911 ESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHS 1970

Query: 1802 PP--TGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPT 1859
             P  T TT    +   +  S ++T ++ +     T            +V P+  T  +  
Sbjct: 1971 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT------------IVLPARSTTSVLL 2018

Query: 1860 HTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFST------AK 1913
                 +  S  SM T  +P  TT        T    +P +  T+ SP+S ++      + 
Sbjct: 2019 GESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEEST 2078

Query: 1914 TSTSLPYHTSSTHHPE--VTPTSTTNITPKHTSTG----TRTPVAHTTSASSSRLPTPFT 1967
            TS S P  T +T  P+   TP  + + T  H+S G    T  P + TTS  S       T
Sbjct: 2079 TSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQE---STT 2135

Query: 1968 THSPPTGSSPFSSTGPMTATSF--QTTTTYPTPSHPQTTL-------------------- 2005
            +HS P  +    S G  TA SF  ++TT + +P    TTL                    
Sbjct: 2136 SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSS 2195

Query: 2006 -----PTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTL-KATGSTH 2059
                  T  P  STS       T   T      T+ S  ST T  V   TT  ++ GST 
Sbjct: 2196 TGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP 2255

Query: 2060 TAP-PMTVTTSGTSQTHSSF-----STATASSSFISSSSWLPQNSSSR--PPSSPITTQL 2111
            T   P + TTSG S+  + F     ++ T  SS  S++S   ++++SR  P S+ ITT L
Sbjct: 2256 TTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT-L 2314

Query: 2112 PHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSS------PQTSSPSVGTSSSF 2165
            P   S TTP    ++ S++F  SP +P+T  S  P+S +S        TS    G++ S 
Sbjct: 2315 P--GSTTTP--GLSEASTTFYSSPRSPTTTLS--PASMTSLGVGEESTTSRSQPGSTHST 2368

Query: 2166 VSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSAL 2225
            VS    STT    S  S + + ++   + + +FP +P  +T++R   P T  S       
Sbjct: 2369 VSPA--STTTPGLSEESTTVYSSSPGSTETTVFPRTP--TTSVRGEEPTTFHS------- 2417

Query: 2226 LPISTVT---VSPTPSSHLASSTIAFPSTPRTT----ASTHTAPAFSSQSTTSRSTSLTT 2278
             P ST T      + +S L   + AFP +P +T     +T T      +STT  S+S +T
Sbjct: 2418 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 2477

Query: 2279 RVPTSGFVSLTSGVTGIPT----SPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAP 2334
                S   S TSG+ G  T    SP +  TT  PG   SPTT  L+   T   ++P S P
Sbjct: 2478 GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPG---SPTTPSLSEKSTTFYTSPRS-P 2533

Query: 2335 VSSLGTPTPTSPGV 2348
             ++L   T TS GV
Sbjct: 2534 DATLSPATTTSSGV 2547



 Score =  272 bits (696), Expect = 3e-72
 Identities = 352/1264 (27%), Positives = 526/1264 (41%), Gaps = 180/1264 (14%)

Query: 1195 PCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSST-GPSPSSNHTPASP--TQ 1251
            P    TTP PP T   P   S      P +  +T     S+T G S  S    +SP  T 
Sbjct: 1587 PSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG 1646

Query: 1252 TPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAS 1311
            T L P   T S  +   GEP     +     T+ LP + T    + K T   ++ R+  +
Sbjct: 1647 TALFP---TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 1703

Query: 1312 TASPATTSTAQSTTRTTMTLPTPATSGT-----SPTLP-----KSTNQELPGTTATQTTG 1361
            T SPA+T+++  +  +T +   P ++ T     S T+P      + +   PG+T T T  
Sbjct: 1704 TLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT-TLS 1762

Query: 1362 PRPTPASTTGPTTP----QPGQPTRPTATETTQTRTTTEYTTPQ-----TPHTTHSPPTA 1412
            P  T AS+ GP +      PG        + T      E +TP      +PHTT SP  A
Sbjct: 1763 PGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP--A 1820

Query: 1413 GSPVPSTGPVTATSFHATT-TYPTP-----SHPETTLPTHVPPFSTSLVTPSTH-TVITP 1465
            GS        T  S+ ++  T P P     +  E +  +H  P ST    P+TH +  + 
Sbjct: 1821 GSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSST----PTTHFSASST 1876

Query: 1466 THAQMATSASNHSAP--TGTIPPPTTLKATGSTHTAPPITPTTSGTSQAH---SSFSTNK 1520
            T  +   S + HS+P  T T P P     +G    +     +   T   H   SS ++ +
Sbjct: 1877 TLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGR 1936

Query: 1521 TPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTR---TPVAH--TNSATSSRPPPPFTT 1575
            +  S  SH+S+TH     P++T+ +   PTS  +    T   H   +S TS R      +
Sbjct: 1937 SEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTAS 1996

Query: 1576 HSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPT 1635
            HS         +TG +   +  TT+     S   TT P       T+ +  ST    TP 
Sbjct: 1997 HSSQ------DATGTIVLPARSTTSVLLGES---TTSPISSGSMETTALPGST---TTPG 2044

Query: 1636 HAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTA---KTST 1692
             ++ +T+   HS P     P TTL    +T +  +   TTS  S+  S+  TA    T+T
Sbjct: 2045 LSEKSTT--FHSSPRS---PATTLSPASTTSSGVSEESTTSH-SRPGSTHTTAFPDSTTT 2098

Query: 1693 SLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQ----------SRSSFST 1742
               S  S+T H+   ST TT + P  T+T  P    TTS +S           S ++ S 
Sbjct: 2099 PGLSRHSTTSHSSPGSTDTT-LLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF 2157

Query: 1743 AKTSTSLHSHTSSTH---HPEVTSTS--TTSITPNHTSTGTRTPVAHTTSATSSRLP--- 1794
             + ST+ HS   STH    P+ T++S    + T  H+STG+        S+TS  L    
Sbjct: 2158 GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGES 2217

Query: 1795 TPFTTHSPPTGTTPISSTGPVTATS-FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTH 1853
            T F TH   T TTP   + P TAT+  + +TTY     P +T  TH P+ ST+       
Sbjct: 2218 TAFQTHPASTHTTP---SPPSTATAPVEESTTYHRS--PGSTPTTHFPASSTTSGHSEKS 2272

Query: 1854 TVIIPTHTQMATS-ASIHSMPTGTIPPPTTIKATGSTH-TAPPMTPTTSGTSQSPSSFST 1911
            T+   +     T+ +S HS  +G     T+  + GST  T  P + TT G S++ ++F +
Sbjct: 2273 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 2332

Query: 1912 AKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSP 1971
            +  S +     +S     V   STT+ +   ++  T +P + TT   S    T +++   
Sbjct: 2333 SPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPG 2392

Query: 1972 PTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQ 2031
             T ++ F  T   +    + TT +  P+   TTL T     ++ L   ST        TQ
Sbjct: 2393 STETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTE-DSTTSGLTEESTAFPGSPASTQ 2451

Query: 2032 MATSASIHSTPTGTVPPPTTLKATGSTHTA-PPMTVTTSGT--SQTHSSFSTATASSSFI 2088
                A++ +   G     T   ++GST T   P   TTSG     T S  S ++  ++ +
Sbjct: 2452 TGLPATLTTADLGE-ESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTL 2510

Query: 2089 SSSSWLPQNSSSRP-----PSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPST--- 2140
              S   P  S         P SP  T    LS ATT  S  ++ SS+    P +  T   
Sbjct: 2511 PGSPTTPSLSEKSTTFYTSPRSPDAT----LSPATTTSSGVSEESSTSHSQPGSTHTTAF 2566

Query: 2141 --------VSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASV 2192
                    +S +  +SHSSP ++  ++  +S+  S P   +T S  S  S  T  +  S 
Sbjct: 2567 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGST 2626

Query: 2193 SA------SPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTI 2246
            +A      S  F SSP ++ T                 L P ST     T S  + +ST 
Sbjct: 2627 TALSFGQESTTFHSSPGSTHT----------------TLFPDST-----TSSGIVEASTR 2665

Query: 2247 AFPST--PRTTAS--THTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTN 2302
               ST  PRTT S  + T+P    +STT ++   +T          T       T+PV  
Sbjct: 2666 VHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHT--------TPSPPSTATAPVEE 2717

Query: 2303 LTTRHPGPTLSPTTRFLTSSLT---------------AHGSTPASAPVSSLG----TPTP 2343
             TT H  P  +PTT F  SS T               A G+TP+SA  ++ G    T + 
Sbjct: 2718 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 2777

Query: 2344 TSPG 2347
             SPG
Sbjct: 2778 ISPG 2781



 Score =  266 bits (679), Expect = 2e-70
 Identities = 372/1346 (27%), Positives = 557/1346 (41%), Gaps = 234/1346 (17%)

Query: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSS----KPTAS 1267
            ++GS  T   P  G++TT GL   +    SS  +PA    T L PA+ TSS    + T S
Sbjct: 3584 SSGSMETTALP--GSTTTPGLSEKSTTFHSSPRSPA----TTLSPASTTSSGVSEESTTS 3637

Query: 1268 SGEPPRPTTAVTPQATS--GLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTT 1325
               P    T   P +T+  GL   +T   ++   T T     +T ++ S   ++T+ S++
Sbjct: 3638 HSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSS 3697

Query: 1326 RTTMTLPTP-ATSGTSPTLPKSTNQELPGTTAT-----QTTGPRPTPASTTGPTTPQPGQ 1379
             +T T  +P +T+  S     +T    PG+T T      TT      AST   ++    +
Sbjct: 3698 GSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 3757

Query: 1380 PTRPTATETT---QTRTTTEYTTPQTPHTTHSPP-TAGSPVP-------STGPVTATSFH 1428
             T   A+ T+   Q  +T   T P + HTT SPP TA +PV        S G    T F 
Sbjct: 3758 TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 3817

Query: 1429 ATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPT 1488
            A++T  T  H E +   H  P ++     S H+  +       +  S  S    T+P  T
Sbjct: 3818 ASST--TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 3875

Query: 1489 T---LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTI 1545
            T   L    +T  + P +PTT+ +  + +S    +  T+  S   STH   V+P STTT 
Sbjct: 3876 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHST-VSPASTTTP 3934

Query: 1546 TPNPTSTR--------TRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSF- 1596
              +  ST         T T V   ++ TS R   P T HS P  +     T   T +   
Sbjct: 3935 GLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLT 3994

Query: 1597 KTTTTYP-TPSHPQTTLPTHVPPF-----STSLVTPSTHTVITPTHAQMATSASI-HSMP 1649
            + +T +P +P+  QT LP  +        ST+  + S  T    + A+  TS  +  S P
Sbjct: 3995 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP 4054

Query: 1650 TGTIPPPTTLKATGSTHTAPTMT--LTTSGTSQAL--SSLNTAKTSTSLHSHTSSTHHAE 1705
            +   P  T       + T P+++   TT  TS     ++L+ A T++S  S  SST H++
Sbjct: 4055 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ 4114

Query: 1706 ATSTSTTNITPNPTSTGTPPMTVTTSGTSQ----------SRSSFSTAKTSTSLHSH--- 1752
              ST TT   P+ T+T       TTS +SQ          S ++ S  + ST+ HS    
Sbjct: 4115 PGSTHTTAF-PDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 4173

Query: 1753 TSSTHHPEVTSTS--TTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTT-HSPPTGTTPI 1809
            T +T  P+ T TS    + TP H+STG+        S+TS+ L    TT  S P+ +   
Sbjct: 4174 TETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTT 4233

Query: 1810 SSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSL----VTPSTHTVIIPTHTQMAT 1865
             S    TA   + +TTY   S P +T  TH  + ST+L     + + H+    T T +  
Sbjct: 4234 PSPPSTTAVPVEVSTTYH--SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFP 4291

Query: 1866 SASIHSMPTGTIPPPTTIKATGSTHT-APPMTPTTSGTSQSPSSFSTAKTS---TSLPYH 1921
            + S  S+  G   P T+  ++GST T A P + TT+G S+  ++F ++  S   T  P  
Sbjct: 4292 TRSATSVLVGE--PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 4349

Query: 1922 TSSTHHPEVTPTSTTNITPKHT----STGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSP 1977
            T+S+   E + TS +     HT    S+ T   V+  ++AS S   +  TT SP  GS+ 
Sbjct: 4350 TTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSP--GSTT 4407

Query: 1978 FSSTGPMTATSFQT-----TTTYP------------TPSH-----PQTTLP--------- 2006
             SS GP + T   +     TT  P            TP H     P TTL          
Sbjct: 4408 ASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG 4467

Query: 2007 --------------THVPPFSTSLV-------------TPSTH-TVIITTHTQMATSASI 2038
                          T  PP +TS               TP+TH +   TT  +   S ++
Sbjct: 4468 ESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 4527

Query: 2039 HSTPTGTVPPPTTLKATGST--------HTAP--------PMTVTTSGTSQ--THSSFST 2080
            HS+P  T   P+  ++T S         H++P        P + TTSG  +  T S  ST
Sbjct: 4528 HSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSST 4587

Query: 2081 ATASSSFISSSSWLPQNSSS--RPPSSPITTQLPHLS----------------------- 2115
                SS  S++S L +  +S    P S  TT  P  S                       
Sbjct: 4588 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 4647

Query: 2116 -------------SATTPVS-----TTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSP 2157
                         S T+P+S     TT    S+ +P  S  ST     PSS  +   S+ 
Sbjct: 4648 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSAS 4707

Query: 2158 SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAA------------- 2204
            S     S  S  VHS+ +++ +  S +   T+  V  S  + SSP +             
Sbjct: 4708 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 4767

Query: 2205 -----STTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTH 2259
                 S T  ++  HTISSP + ++ L     +   +P S    +T  FP +  T+  + 
Sbjct: 4768 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS---IATTHFPESSTTSGRSE 4824

Query: 2260 TAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFL 2319
             + A  S   T+  T L     TSG ++ ++     P S  T L +    P LS  +  L
Sbjct: 4825 ESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTIL 4884

Query: 2320 TSSLTAHGST--PASAPVSSL-GTPT 2342
             SS  +   T  PAS   SS+ G PT
Sbjct: 4885 YSSSRSPDQTLSPASMTSSSISGEPT 4910



 Score =  264 bits (675), Expect = 7e-70
 Identities = 344/1238 (27%), Positives = 515/1238 (41%), Gaps = 179/1238 (14%)

Query: 1195 PCMPPTTPQPPTTP----QLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPT 1250
            P    TTP PPTT     +L TT        P T  S +   L  +  S + + +P +  
Sbjct: 3393 PNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 3452

Query: 1251 QTPLLPATLTSS----KPTASSGEPPRPTTAVTPQA--TSGLPPTATLRSTATKPTVTQA 1304
             TP  PA  T+S    + T     P    T   P++  TSG    +T   ++T  T++ A
Sbjct: 3453 TTPS-PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 3511

Query: 1305 TTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKS-TNQELPGTTA--TQTTG 1361
             +  +A    P +  ++  +T TT    +  TSG S     S ++Q+  GT     ++T 
Sbjct: 3512 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 3571

Query: 1362 PRPTPASTTGP-------TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGS 1414
                  STT P       TT  PG  T P  +E    ++TT +++P++P TT SP +  S
Sbjct: 3572 SVLLGESTTSPISSGSMETTALPGSTTTPGLSE----KSTTFHSSPRSPATTLSPASTTS 3627

Query: 1415 PVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTP--STHTVITPTHAQMAT 1472
                    +  S  +TT++  P        TH   F  S  TP  S H            
Sbjct: 3628 --------SGVSEESTTSHSRPGS------THTTAFPDSTTTPGLSRH------------ 3661

Query: 1473 SASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQ----AHSSFSTNKTPTSLHSH 1528
            S ++HS+P  T    TTL          P + TTSG+SQ    +HSS  +  T  S  S 
Sbjct: 3662 STTSHSSPGST---DTTLL---------PASTTTSGSSQESTTSHSSSGSTDTALSPGST 3709

Query: 1529 T-------SSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTG 1581
            T       S+T H     T TT    + TS+         +S+T S    P TT SP + 
Sbjct: 3710 TALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGS----PRTTLSPASS 3765

Query: 1582 SSPFSSTGPMTATSFKTTTTYPTPSHPQT-TLPT------HVPPFSTSLVTPSTHTVITP 1634
            +SP    G  TA      +T+ TPS P T T P       H  P ST    P+TH   + 
Sbjct: 3766 TSP-GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST----PTTHFPASS 3820

Query: 1635 THAQMATSASI-HSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTS 1693
            T +  +  ++I HS P  +   P++  +T S     T +  + G+++ +++L  + T+  
Sbjct: 3821 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE-ITTLPGSTTTPG 3879

Query: 1694 LHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT-SGTSQSRSSFSTAKTSTSLHSH 1752
            L S  S+T ++   S +TT    + TS G    + T+ S    + S+ S A T+T   S 
Sbjct: 3880 L-SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 3938

Query: 1753 TSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTT-SATSSRLPTPFTTHSPPTGTTPISS 1811
             S+T +     ++ T++ P  T+T  R     T  S  +S   T FT  S  +G T  S+
Sbjct: 3939 ESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 3998

Query: 1812 TGPVTATSFQT--------------TTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVII 1857
              P +  S QT              +TT+P+ S    T  +   S ++ LV  ST + + 
Sbjct: 3999 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS 4058

Query: 1858 PTHTQMATSASIHSMPTGTIPPPTTIKATGSTH-TAPPMTPTTSGTSQSPSSFSTAKTST 1916
            P+ T+  T     + P+ +    T   +  S   T  P T T+SG S+  S      TS 
Sbjct: 4059 PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESS------TSH 4112

Query: 1917 SLPYHTSSTHHPEVTPTSTTNITP--KHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTG 1974
            S P  T +T  P+ T TS  +  P   H+S G+        S ++S L    TT     G
Sbjct: 4113 SQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 4172

Query: 1975 SSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMAT 2034
             +  +     T TS     + PT S   +   T  P  STS       T      T  + 
Sbjct: 4173 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEEST------TFQSW 4226

Query: 2035 SASIHSTPTGTVPPPTT---LKATGSTHTAPPMTVTT----SGTSQTHSSFSTATASSSF 2087
             +S  +TP+   PP TT   ++ + + H+ P  T TT    S T+   S  ST   SS  
Sbjct: 4227 PSSSDTTPS---PPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPG 4283

Query: 2088 ISSSSWLPQNSSS-----RPPSSPI------TTQLPHLSS-------ATTPVSTTNQLSS 2129
             + ++  P  S++      P +SPI      TT LP  ++       +TT  S+     +
Sbjct: 4284 ATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDT 4343

Query: 2130 SFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTT 2189
            + SP+ +  S VS    +SHS P +   +   SS+ +      +T S  S  S  T  + 
Sbjct: 4344 TLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSP 4403

Query: 2190 ASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFP 2249
             S +AS L P S    ++  +T    +    T S LL  ST   S T S H   S     
Sbjct: 4404 GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAG-- 4461

Query: 2250 STPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPG 2309
            ST R   ST     F S    S+ T+      TS FV L+              TT H  
Sbjct: 4462 STTRQGEST----TFQSW-PNSKDTTPAPPTTTSAFVELS--------------TTSHGS 4502

Query: 2310 PTLSPTTRFLTSSLT----AHGSTPASAPVSSLGTPTP 2343
            P+ +PTT F  SS T       +T  S+PV++  TP+P
Sbjct: 4503 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 4540



 Score =  259 bits (663), Expect = 2e-68
 Identities = 346/1228 (28%), Positives = 528/1228 (42%), Gaps = 178/1228 (14%)

Query: 1194 VPCMPPTTPQPPTT------PQLPTTGSRP--TQVWPMTGTSTTIGLLSSTGPSPSSNHT 1245
            +P    TT  P TT      P+  T  S P  T+   +   +TT GLL ++ P  SS  +
Sbjct: 342  IPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGS 401

Query: 1246 PASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQAT 1305
            P +         TL+ S  T   GEP       T Q+      T+   S  T   V  +T
Sbjct: 402  PHT---------TLSPSSSTTHEGEP------TTFQSWPSSKDTSPAPSGTTSAFVKLST 446

Query: 1306 TRATASTASPATTSTAQSTTR--------------TTMTLPTPATSGTSPTLPKST-NQE 1350
            T  ++ +++P T  +A STT                T T P PA S TS  + +ST    
Sbjct: 447  TYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHR 506

Query: 1351 LPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPP 1410
             PG+T T      P  ++T+G +     + +      TT T+++T  TT    HT++   
Sbjct: 507  SPGSTQTMHF---PESSTTSGHS-----EESATFHGSTTHTKSSTPSTTAALAHTSYHSS 558

Query: 1411 TAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1470
               +        +  S  +  +  + S P+    T +P  ST  V     T    +   M
Sbjct: 559  LGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSM 618

Query: 1471 ATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTS 1530
             T+A     P  T  P  + K+T  T  + P +P T+    + +S   ++  T+ HS   
Sbjct: 619  ETTA----LPGSTTKPGLSEKST--TFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPG 672

Query: 1531 STHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGP 1590
            STH         TT  P  T   T   ++  ++A+ S P P  TT SP  GS+  SS GP
Sbjct: 673  STH---------TTAFPGST---TMPGLSQESTASHSSPGPTDTTLSP--GSTTASSLGP 718

Query: 1591 MTAT-----SFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITP--THAQMATSA 1643
               T         TT  P  +     L   +P  S+   T S HT ++P  +  +   S 
Sbjct: 719  EYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSS---TRSPHTTLSPAGSTTRQGEST 775

Query: 1644 SIHSMPTG--TIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSST 1701
            + HS P+   T P P T   T S    P+ T   S +S   + + +A+++TS     S+T
Sbjct: 776  TFHSWPSSKDTRPAPPT---TTSAFVEPSTTSHGSPSSIPTTHI-SARSTTSGLVEESTT 831

Query: 1702 HHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEV 1761
            +H+   ST T +   + T++G    + T+   S +  + S+A ++TS      +++H   
Sbjct: 832  YHSSPGSTQTMHFPESDTTSGRGEESTTSH--SSTTHTISSAPSTTSALVEEPTSYHSSP 889

Query: 1762 TSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPI----SSTGPVTA 1817
             ST+TT    + T++G     +  ++A+ S      T   P   TT +    S+T P+++
Sbjct: 890  GSTATTHFPDSSTTSGR----SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 945

Query: 1818 TSFQTT-----TTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSM 1872
             S +TT     TT P  S   TT  +   S +T+L   ST            TS+ +   
Sbjct: 946  GSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST------------TSSGVSEE 993

Query: 1873 PTGTIPPPTTIKATGSTH-TAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931
             T      T+    GSTH TA P + TT G S+       + TS S P  T +T  P  T
Sbjct: 994  ST------TSRSRPGSTHTTAFPDSTTTPGLSRH------STTSHSSPGSTDTTLLPAST 1041

Query: 1932 PTS--TTNITPKHTSTG---TRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTA 1986
             TS  +   T  H+S+G   T      TT+ S  +  T F ++   T ++ F  +   + 
Sbjct: 1042 TTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSG 1101

Query: 1987 TSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTV 2046
                +T  + +   P+TTL    P  STS       T   T      T+ S  ST T  V
Sbjct: 1102 IVEASTRVHSSTGSPRTTLS---PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPV 1158

Query: 2047 PPPTTL-KATGSTHTAP-PMTVTTSGTSQTHSSF-----STATASSSFISSSSWLPQNSS 2099
               TT  ++ GST T   P + TTSG S+  + F     ++ T  SS  S++S   ++++
Sbjct: 1159 EESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT 1218

Query: 2100 SR--PPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSS------ 2151
            SR  P S+ ITT LP   S TTP    ++ S++F  SP +P+T  S  P+S +S      
Sbjct: 1219 SRISPGSTEITT-LP--GSTTTP--GLSEASTTFYSSPRSPTTTLS--PASMTSLGVGEE 1271

Query: 2152 PQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRAT 2211
              TS    G++ S VS    STT    S  S + + ++   + + +FP S   +T++   
Sbjct: 1272 STTSRSQPGSTHSTVSPA--STTTPGLSEESTTVYSSSRGSTETTVFPHS--TTTSVHGE 1327

Query: 2212 LPHTISSPFTLSALLPISTVT---VSPTPSSHLASSTIAFPSTPRTT----ASTHTAPAF 2264
             P T  S        P ST T      + +S L   + AFP +P +T     +T T    
Sbjct: 1328 EPTTFHS-------RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADL 1380

Query: 2265 SSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPT----SPVTNLTTRHPGPTLSPTTRFLT 2320
              +STT  S+S +T    S   S TSG+ G  T    SP +  TT  PG   SPTT  L+
Sbjct: 1381 GEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPG---SPTTPSLS 1437

Query: 2321 SSLTAHGSTPASAPVSSLGTPTPTSPGV 2348
               T   ++P S P ++L   T TS GV
Sbjct: 1438 EKSTTFYTSPRS-PDATLSPATTTSSGV 1464



 Score =  256 bits (653), Expect = 2e-67
 Identities = 357/1324 (26%), Positives = 542/1324 (40%), Gaps = 228/1324 (17%)

Query: 1194 VPCMPPTTPQPPTTPQLPTTGSRP----TQVWPMTGTSTTIGLLSSTGPS-PSSNHTPAS 1248
            +  +P +T  P  +    T  S P    T + P + TS  +G  S+T  S P S H+  S
Sbjct: 3868 ITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 3927

Query: 1249 PTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGL-----PPTATLRSTATKPTV-- 1301
            P  T      L+    T  S  P    T V P++T+       P T   R  +T  T+  
Sbjct: 3928 PASTTT--PGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFT 3985

Query: 1302 -----TQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTA 1356
                 +  T  +TA   SPA+T T    T TT  L   +T  T P+   ST  +L    +
Sbjct: 3986 EDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEEST--TFPSSSGSTGTKLSPARS 4043

Query: 1357 T------QTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPP 1410
            T      ++T  R +P+ST   TT  PG PT P+ +E    ++TT YT+P++P  T SP 
Sbjct: 4044 TTSGLVGESTPSRLSPSSTE--TTTLPGSPTTPSLSE----KSTTFYTSPRSPDATLSPA 4097

Query: 1411 TAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1470
            T  S   S    T+ S   +T         TT      P ++     ST   ++P     
Sbjct: 4098 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTA 4157

Query: 1471 AT----SASNHSAPTGT----IPPPT-----------TLKATGSTHTA-PPITPTTSGTS 1510
            ++    S + HS+P  T    +P  T           T  +TGS HT   P + T++G  
Sbjct: 4158 SSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQ 4217

Query: 1511 QAHSSF-----STNKTP-----TSLHSHTSSTHH--PEVTPT-----STTTITPNPTSTR 1553
            +  ++F     S++ TP     T++    S+T+H  P  TPT     S+TT+  +  ST 
Sbjct: 4218 EESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTT 4277

Query: 1554 -------TRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTAT---SFKTTTTYP 1603
                   T T +  T SATS     P TT    +GS+  ++    T T   S K+TT Y 
Sbjct: 4278 VHSSPGATGTALFPTRSATSVLVGEP-TTSPISSGSTETTALPGSTTTAGLSEKSTTFYS 4336

Query: 1604 TPSHPQTTLPT----------------------HVPPFSTSLVTP--------------S 1627
            +P  P TTL                        H   F +S   P              S
Sbjct: 4337 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGS 4396

Query: 1628 THTVITPTHAQMAT----SASIHSMPTGT----IPPPTTLK-----------ATGSTHT- 1667
            T T ++P     ++    S + HS P  T    +P  TT             +TGS HT 
Sbjct: 4397 TDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTT 4456

Query: 1668 -APTMTLTTSGTSQALSSLNTAK-------TSTSLHSHTSSTHHAEATSTSTTNITPNPT 1719
             +P  + T  G S    S   +K       T+TS     S+T H   +ST TT+ + + T
Sbjct: 4457 LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASST 4516

Query: 1720 STG----------TPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSST---HHPEVTSTST 1766
            + G          +P  T TT   ++S +S    + ST+ HS   ST   H PE  +TS 
Sbjct: 4517 TLGRSEESTTVHSSPVATATTPSPARSTTS-GLVEESTTYHSSPGSTQTMHFPESNTTSG 4575

Query: 1767 TSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPP--TGTTPISSTGPVTATSFQTTT 1824
                   + + T   ++   S TS+ +  P + HS P  T TT    +   +  S ++T 
Sbjct: 4576 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTA 4635

Query: 1825 TYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIK 1884
            ++ +     T +   +P+ ST+ V     T    +   M T+A    +P  T  P  + K
Sbjct: 4636 SHSSQDATGTIV---LPARSTTSVLLGESTTSPISSGSMETTA----LPGSTTTPGLSEK 4688

Query: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTST--SLPYHTSSTHHPEVTPTS--TTNITP 1940
            +T + H++P  TPTT  ++ S +   + +++T  S P  T++T  P  + TS      T 
Sbjct: 4689 ST-TFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTA 4747

Query: 1941 KHTSTG-TRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPS 1999
             H+S G T+T     +S +S R     T+HS  T +   SS    T+   +  T+Y   S
Sbjct: 4748 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHT--ISSPPSTTSALVEEPTSYH--S 4803

Query: 2000 HPQTTLPTHVPPFSTSLVTPSTHTVIITT-HTQMATSASIHSTPTGTVPPPTTLKAT-GS 2057
             P +   TH P  ST+       T   ++  T   T    H T +G +   TT   + GS
Sbjct: 4804 SPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGS 4863

Query: 2058 THTAPPMTVTTSGTSQTHSS-FSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS 2116
              T    T TT G S   +  +S++ +    +S +S    + S  P S     +  H ++
Sbjct: 4864 METTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTA 4923

Query: 2117 --ATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTT 2174
              A+T  S  +Q S++F   P +  T             T SP   T+SSF       TT
Sbjct: 4924 FPASTTTSGLSQESTTFHSKPGSTET-------------TLSPGSITTSSFAQ---EFTT 4967

Query: 2175 LSSGSHSSLST-HPTTASVSA----SPLFPSSPAASTTIRATLPHTISSPFTLSALLPIS 2229
              S   S+LST  P + +V      S  F SSP ++ T          + F+ S  + I 
Sbjct: 4968 PHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTET----------TAFSHSNTMSIH 5017

Query: 2230 TVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLT 2289
            +   +P P S   + T+  P+T  TT     + AF S S  + +T L  R       S  
Sbjct: 5018 SQQSTPFPDSPGFTHTV-LPATLTTTDIGQESTAFHSSSDATGTTPLPAR-------STA 5069

Query: 2290 SGVTGIPT----SPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345
            S + G PT    SP    TT  P    S T+     S T H S   ++ + S  +    +
Sbjct: 5070 SDLVGEPTTFYISPSPTYTTLFPAS--SSTSGLTEESTTFHTSPSFTSTIVSTESLETLA 5127

Query: 2346 PGVC 2349
            PG+C
Sbjct: 5128 PGLC 5131



 Score =  255 bits (651), Expect = 4e-67
 Identities = 391/1362 (28%), Positives = 564/1362 (41%), Gaps = 264/1362 (19%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSST--GPSPSSNHTPASPTQ--TPLL 1255
            TT    +TP      +  +    +  T TT    SST  G S  S  + +SP    T +L
Sbjct: 536  TTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVL 595

Query: 1256 PATLTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASP 1315
            PA  T S     S   P          +SG   T  L  + TKP +++ +T   +S  SP
Sbjct: 596  PAGSTPSVLVGDSTPSP---------ISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSP 646

Query: 1316 ATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQE-LPGTTATQTTGPRPTPA-STTGPT 1373
             TT    S T + ++      S TS + P ST+    PG+T         T + S+ GPT
Sbjct: 647  DTTHLPASMTSSGVS----EESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPT 702

Query: 1374 --TPQPGQPT-------------RPTATETTQTRTTTE-----------YTTPQTPHTTH 1407
              T  PG  T             RP +TETT     T            +++ ++PHTT 
Sbjct: 703  DTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTL 762

Query: 1408 SPPTAGSPVPSTGPVTATSFHA-TTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPT 1466
            SP  AGS   +T    +T+FH+  ++  T   P TT    V P +TS  +PS+     PT
Sbjct: 763  SP--AGS---TTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSS----IPT 813

Query: 1467 HAQMATSASNHSAPTGTIPPPTTLKAT-GSTHTAP-PITPTTSGTSQAHSSFSTNKTPTS 1524
                 T  S  S  +G +   TT  ++ GST T   P + TTSG  +  ++         
Sbjct: 814  -----THISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTT--------- 859

Query: 1525 LHSHTSSTHHPEVTPTSTTTITPNPTSTRTR---TPVAH--TNSATSSRPPPPFTTHSPP 1579
              SH+S+TH     P++T+ +   PTS  +    T   H   +S TS R      +HS  
Sbjct: 860  --SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 917

Query: 1580 TGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQM 1639
                   +TG +   +  TT+     S   TT P       T+ +  ST    TP  ++ 
Sbjct: 918  ------DATGTIVLPARSTTSVLLGES---TTSPISSGSMETTALPGST---TTPGLSER 965

Query: 1640 ATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGT---SQALSSLNTAKTSTSLHS 1696
            +T+   HS P     P TTL    +T +  +   TTS +   S   ++   + T+  L  
Sbjct: 966  STT--FHSSPRS---PATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSR 1020

Query: 1697 HTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQ----------SRSSFSTAKTS 1746
            H++ T H+   ST TT + P  T+T  P    TTS +S           S ++ S  + S
Sbjct: 1021 HST-TSHSSPGSTDTT-LLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQES 1078

Query: 1747 TSLHSHTSSTH---HPEVTSTS--TTSITPNHTSTGTRTPVAHTTSATSSRL---PTPFT 1798
            T+ HS+  STH    P+ T++S    + T  H+STG+        S+TS  L    T F 
Sbjct: 1079 TTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQ 1138

Query: 1799 THSPPTGTTPISSTGPVTATS-FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVII 1857
            TH   T TTP   + P TAT+  + +TTY     P +T  TH P+ ST+       T+  
Sbjct: 1139 THPASTHTTP---SPPSTATAPVEESTTY--HRSPGSTPTTHFPASSTTSGHSEKSTIFH 1193

Query: 1858 PTHTQMATS-ASIHSMPTG-----------------TIPPPTT---IKATGSTHTAPPMT 1896
             +     T+ +S HS  +G                 T+P  TT   +    +T  + P +
Sbjct: 1194 SSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS 1253

Query: 1897 PTTSGTSQSPSSFSTAK---TSTSLPYHTSSTHHPEVTPT------STTNITPKHTSTGT 1947
            PTT+ +  S +S    +   TS S P  T ST  P  T T      STT  +    ST T
Sbjct: 1254 PTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTET 1313

Query: 1948 RTPVAHTTSAS-------------SSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT--- 1991
             T   H+T+ S             +S   T FT  S  +G +  S+  P +  S QT   
Sbjct: 1314 -TVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP 1372

Query: 1992 -----------TTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMAT------ 2034
                       +TT+P+ S    T  +     ++ LV  ST + +  + T+  T      
Sbjct: 1373 ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 1432

Query: 2035 --SASIHST--------PTGTVPPPTTLKA------------TGSTH-TAPPMTVTTSGT 2071
              S S  ST        P  T+ P TT  +             GSTH TA P + TTS  
Sbjct: 1433 TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDL 1492

Query: 2072 SQ----THSS-FSTATASSSFISSSSWLPQNSSS--RPPSSPITTQLPH------LSSAT 2118
            SQ    +HSS  ST    S   +++S L Q S++    P    TT LP       L  A+
Sbjct: 1493 SQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAS 1552

Query: 2119 TPV-STTNQLSSSFSPSPSA------PSTVSSYVPSSH----SSPQTSSPSVGTSSSFVS 2167
            TP  S+T  L ++ +P+ S        ST     PSS     S P T++  V  S+++ S
Sbjct: 1553 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHS 1612

Query: 2168 APVHS-TTLSSGSHSSLSTHPTTASVSASP------LFPSSPAASTTIRATLPHTISSPF 2220
             P  + TT  S S ++L     + +V +SP      LFP+  A S  +       ISS  
Sbjct: 1613 RPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGS 1672

Query: 2221 TLSALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRS---TSLT 2277
            T +  LP ST T   +  S    S+   P T  + AST T+   S +STTS S   ++ T
Sbjct: 1673 TETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAST-TSSGVSEESTTSHSRPGSTHT 1731

Query: 2278 TRVPTSGFV-SLTSGVTGIPTSPVTNLTTRHPGPTL----------------SPTTRFLT 2320
            T  P S  +  ++   T   +SP +  TT  PG T                 S  T  L 
Sbjct: 1732 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLP 1791

Query: 2321 SSLTAHGSTPASAPV-SSLGTPTPTSPGVCSVREQQEEITFK 2361
             + TA G   AS PV SS G+P  T     S   Q E  TF+
Sbjct: 1792 DNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ 1833



 Score =  236 bits (602), Expect = 2e-61
 Identities = 300/1152 (26%), Positives = 477/1152 (41%), Gaps = 135/1152 (11%)

Query: 1161 LCPSQPQS--VPGSNIEGCYNCSQDEYFDHEEGVCVPCMPPTTPQPPTTPQLPTTGSRP- 1217
            L PS  ++  +PGS      +     ++           P TT     + +  T+ S+P 
Sbjct: 4057 LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG 4116

Query: 1218 -TQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSS----KPTASSGEPP 1272
             T       ++TT GL       P+++H+    T+  L P + T+S    + T     P 
Sbjct: 4117 STHTTAFPDSTTTSGL----SQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 4172

Query: 1273 RPTTAVTPQ--ATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMT 1330
               T + P    TSGL   +T   ++T    T  T  ++ ST     ++T QS   ++ T
Sbjct: 4173 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDT 4232

Query: 1331 LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQ 1390
             P+P ++   P    +T    P +T T       T    +  +T     P   T T    
Sbjct: 4233 TPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGA-TGTALFP 4291

Query: 1391 TRTTTEYTTPQTPHTTHSPPTAGSP----VPSTGPVTATSFHATTTYPTPSHPETTLPTH 1446
            TR+ T     +    T SP ++GS     +P +      S  +TT Y +P  P+TTL   
Sbjct: 4292 TRSATSVLVGEP---TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS-- 4346

Query: 1447 VPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTT 1506
             P  +TS       T        M T+A     P+ T  P  + ++T S H++P  T TT
Sbjct: 4347 -PASTTSSGVSEESTTSHSRPGSMHTTAF----PSSTTMPGVSQESTAS-HSSPGSTDTT 4400

Query: 1507 SGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS 1566
                      S   T  S     S+T H     T TT +  N T++         +S+T 
Sbjct: 4401 ---------LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTG 4451

Query: 1567 SRPPPPFTTHSPP--TGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPT--HVPPFSTS 1622
            S    P TT SP   T     S+T      S  TT   PT +     L T  H  P ST 
Sbjct: 4452 S----PHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSST- 4506

Query: 1623 LVTPSTH-TVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTS-GTSQ 1680
               P+TH +  + T  +   S ++HS P  T   P+  ++T S     + T  +S G++Q
Sbjct: 4507 ---PTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQ 4563

Query: 1681 AL----SSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQS 1736
             +    S+  + +   S  SH+S+TH   +  ++T+ +   PTS  + P +  T+    S
Sbjct: 4564 TMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS 4623

Query: 1737 RSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSI-----TPNHTSTGTRTPVAHTTSATSS 1791
             ++   ++ ST+ HS   +T    + + STTS+     T +  S+G+    A   S T+ 
Sbjct: 4624 STTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP 4683

Query: 1792 RLPTPFTT-HSPP--TGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLV 1848
             L    TT HS P  T TT  S++      S ++TT + +P    TT P+   S ++ LV
Sbjct: 4684 GLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATT-PSPARSTTSGLV 4742

Query: 1849 TPSTHTVIIPTHTQMATSASIHSMP--TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSP 1906
              ST               + HS P  T T+  P +  A+G +  +     +T+ T  SP
Sbjct: 4743 EEST---------------AYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 4787

Query: 1907 SSFSTAKTSTSLPYHTS-----STHHPEVTPTS--TTNITPKHTSTGTR--TPV-AHTTS 1956
             S ++A       YH+S     +TH PE + TS  +   T  H+S  T   TP+ AH T+
Sbjct: 4788 PSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 4847

Query: 1957 ASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSL 2016
            +      T F   SP +  +  +ST      S ++T  Y +   P  TL           
Sbjct: 4848 SGRIAESTTFYI-SPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTL----------- 4895

Query: 2017 VTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTH-TAPPMTVTTSGTSQTH 2075
             +P++            TS+SI   PT      +      STH TA P + TTSG SQ  
Sbjct: 4896 -SPAS-----------MTSSSISGEPT------SLYSQAESTHTTAFPASTTTSGLSQES 4937

Query: 2076 SSFSTATASSSFISSSSWLPQNSSSR---PPSSPITTQLPHLSSATTPVSTTNQLSSSFS 2132
            ++F +   S+    S   +  +S ++    P S   + L  +S A+T V   ++ S++F 
Sbjct: 4938 TTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFY 4997

Query: 2133 PSPSAPSTVS---SYVPSSHSSPQTSSP-SVGTSSSFVSAPVHSTTLSSGSHSSLSTHPT 2188
             SP +  T +   S   S HS   T  P S G + + + A + +T +      S + H +
Sbjct: 4998 SSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDI---GQESTAFHSS 5054

Query: 2189 TASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAF 2248
            + +   +PL P+   AS  +       IS   T + L P S+ T   T  S    ++ +F
Sbjct: 5055 SDATGTTPL-PARSTASDLVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSF 5113

Query: 2249 PSTPRTTASTHT 2260
             ST  +T S  T
Sbjct: 5114 TSTIVSTESLET 5125



 Score =  168 bits (426), Expect = 5e-41
 Identities = 244/887 (27%), Positives = 368/887 (41%), Gaps = 170/887 (19%)

Query: 1560 HTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPF 1619
            +T SA++     PFTT S   G S    TG      F  ++T     H + +  +H  P 
Sbjct: 176  NTTSASTPSSSDPFTTFSD-YGVSVTFITGSTATKHFLDSST--NSGHSEESTVSHSGPG 232

Query: 1620 STSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPT--TLKATGSTHTAPTMTLTTSG 1677
            +T        T + P+H+  ATS  +    T  I   +  T    GST TA     +T+ 
Sbjct: 233  ATG-------TTLFPSHS--ATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTF 283

Query: 1678 TSQALS---SLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTS 1734
             S   S   +L+ A+T++S  S  S+T H+           P PT T   P + T  G S
Sbjct: 284  YSSPRSPDRTLSPARTTSSGVSEKSTTSHSR----------PGPTHTIAFPDSTTMPGVS 333

Query: 1735 QSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLP 1794
            Q     STA  S S+   T +T  P  T+ S  S+ P  T+  +      TT     RLP
Sbjct: 334  QE----STA--SHSIPGSTDTTLSPGTTTPS--SLGPESTTFHSSPGYTKTT-----RLP 380

Query: 1795 TPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPT------------HVPS 1842
               TT      +TP+ S+     T    TT  P+ S  H   PT              PS
Sbjct: 381  DNTTTSGLLEASTPVHSS-----TGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPS 435

Query: 1843 FSTSLV-------------TPSTHTVIIPT---HTQMATSASIHSMPTGTIPPPTTIKAT 1886
             +TS               TP+TH     T   H++ +T      + T T PPP     +
Sbjct: 436  GTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATS 495

Query: 1887 G------STHTAP--------PMTPTTSGTSQSPSSF--STAKTSTSLPYHTS----STH 1926
            G      + H +P        P + TTSG S+  ++F  ST  T +S P  T+    +++
Sbjct: 496  GHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSY 555

Query: 1927 HPEVTPTSTTNITPKHTSTG-----------------TRTPVAHTTSA-SSSRLPTPFTT 1968
            H  +  T TT+     T +G                 T  P   T S       P+P ++
Sbjct: 556  HSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISS 615

Query: 1969 HSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTT-LPTHVPPFSTSLVTPSTHTVIIT 2027
             S  T + P S+T P    S ++TT Y +P  P TT LP  +     S  + ++H+   +
Sbjct: 616  GSMETTALPGSTTKP--GLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGS 673

Query: 2028 THTQMATSA------SIHSTPTGTVPPPT-TLKATGSTHTA---PPMTVTTSGTSQTHSS 2077
            THT     +      S  ST + + P PT T  + GST  +   P  T   S    T ++
Sbjct: 674  THTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETT 733

Query: 2078 FSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTT-NQLSSSFSPSPS 2136
                  ++S +  +S +P +SS+R   SP TT  P  S+     STT +   SS    P+
Sbjct: 734  LLPDNTTASGLLEAS-MPVHSSTR---SPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPA 789

Query: 2137 APSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASP 2196
             P+T S++V       + S+ S G+ SS  +  + + + +SG     +T+ ++   + + 
Sbjct: 790  PPTTTSAFV-------EPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 842

Query: 2197 LFPSSPAA------STTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFPS 2250
             FP S         STT  ++  HTISS               +P+ +S L     ++ S
Sbjct: 843  HFPESDTTSGRGEESTTSHSSTTHTISS---------------APSTTSALVEEPTSYHS 887

Query: 2251 TPRTTASTH-----TAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTG-IPTSPVTN-- 2302
            +P +TA+TH     T    S +ST S S+   T        S TS + G   TSP+++  
Sbjct: 888  SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 947

Query: 2303 -LTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGV 2348
              TT  PG T   TT  L+   T   S+P S P ++L   + TS GV
Sbjct: 948  METTALPGST---TTPGLSERSTTFHSSPRS-PATTLSPASTTSSGV 990



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 94/295 (31%), Positives = 129/295 (43%), Gaps = 36/295 (12%)

Query: 2074 THSSFSTATASSSFISSSSWLPQNSSSRPPSS-PITTQLPH---LSSATTPVSTTNQLSS 2129
            T S FS  T S+  +++S      S+S P SS P TT   +   ++  T   +T + L S
Sbjct: 157  TFSGFSQITGST--VNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDS 214

Query: 2130 SFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHST-TLSSGSHSSLSTHPT 2188
            S +   S  STVS   P +  +  T  PS   +S FV  P  S  T +S   ++L    T
Sbjct: 215  STNSGHSEESTVSHSGPGATGT--TLFPSHSATSVFVGEPKTSPITSASMETTALPGSTT 272

Query: 2189 TASVSA-SPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIA 2247
            TA +S  S  F SSP +          T+S   T S+ +   + T    P     + TIA
Sbjct: 273  TAGLSEKSTTFYSSPRSPD-------RTLSPARTTSSGVSEKSTTSHSRPGP---THTIA 322

Query: 2248 FPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRH 2307
            FP +        T P  S +ST S S      +P S   +L+ G T  P+S     TT H
Sbjct: 323  FPDST-------TMPGVSQESTASHS------IPGSTDTTLSPGTT-TPSSLGPESTTFH 368

Query: 2308 PGPTLSPTTRFLTSSLTAHGSTPASAPV-SSLGTPTPTSPGVCSVREQQEEITFK 2361
              P  + TTR L  + T  G   AS PV SS G+P  T     S   + E  TF+
Sbjct: 369  SSPGYTKTTR-LPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQ 422


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score =  279 bits (714), Expect = 2e-74
 Identities = 336/1240 (27%), Positives = 514/1240 (41%), Gaps = 108/1240 (8%)

Query: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEP 1271
            TT +  ++V   +  S+   +  + G + ++  T  S T T L+ A+ T++  TA S   
Sbjct: 8    TTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT 67

Query: 1272 -PRPT-----------TAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTS 1319
             P PT           + +T  +T+G   T    + +   T + A + +T STA   TT+
Sbjct: 68   TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTT 127

Query: 1320 TAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP-TTPQPG 1378
             + + T TTM     +  G+  T   +T+ E   TT T T G   T  ST G  TT    
Sbjct: 128  VSITGTETTMV----SAMGSETTTNSTTSSE---TTVTSTAGSETTTVSTVGSETTTAYT 180

Query: 1379 QPTRPTATETTQTRTTTEYTTPQ---TPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPT 1435
              +  TA  TT +  TT +T      TP T  S  T  S   S     +T+   TTT  T
Sbjct: 181  ADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST 240

Query: 1436 PSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTI----PPPTTLK 1491
             +H ETT  + +   +T + T  + T ++ T     T+AS   + T T        TT  
Sbjct: 241  -AHSETTAASTMGSETTKVSTAGSETTVS-TAGSETTAASTEDSETNTAFTEDSKTTTAS 298

Query: 1492 ATGSTHTAPPIT---PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPN 1548
             TG   TA   T   PT + T  + ++ ++   P +    T+S+    V    + TI  +
Sbjct: 299  TTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRAS 358

Query: 1549 PTSTRTRTPVAHTNSATS------SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTY 1602
               + T T V+ T S T+      S      TT S  T +S   S     +T     TT 
Sbjct: 359  TVGSETTT-VSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTV 417

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT--GTIPPPTTLK 1660
             T     TT+       +T+    S  T ++ T  +  T+++  S  T   T    TT  
Sbjct: 418  STTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT-- 475

Query: 1661 ATGSTHTAPTMTLTTSG----TSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI-T 1715
             T ST  + T T+TT+G    T+    S  T  ++T L + T  T  ++ T+ ST    T
Sbjct: 476  -TASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 534

Query: 1716 PNPTSTGTPPMTVTTSG----TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITP 1771
               ++TG+   TV+T G    T  +  S +T  ++T L + T+ST   E+T+ STT    
Sbjct: 535  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 594

Query: 1772 NHTST-GTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPS 1830
               ST G+ T  A T  + ++ + T  + ++  T +T  S T   + T  +TTT   T S
Sbjct: 595  TTDSTEGSGTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSS 652

Query: 1831 HPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTH 1890
               TT  +   S +T++ T  + T ++ T     T  S     T      TT+ ATGS  
Sbjct: 653  E--TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET------TTVSATGSET 704

Query: 1891 TAPPM---TPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTS------TTNITPK 1941
            T       T T S T    +  ST  + T+    T+ST   E+T  S      TT  T  
Sbjct: 705  TVSTEGSGTTTVSITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEG 760

Query: 1942 HTSTGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPS 1999
              +T   T  + TTSAS+  S   T  TT S  T +S   S   M +T    TT   T S
Sbjct: 761  SETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTAS 820

Query: 2000 HPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQ---MATSASIHSTPTGTVPPPTTLKATG 2056
               TT+ T     + +  T S  T + T  ++    +T+ S  +T T T    TT  +T 
Sbjct: 821  SKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTE 880

Query: 2057 STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS 2116
             + T    T ++  T+ T     T TAS+    +++   + S         TT      S
Sbjct: 881  GSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSE--------TTTASTEGS 932

Query: 2117 ATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLS 2176
              T VSTT   +++ S   S  +T      S+  S  T+  + G+ +  VSA    TT  
Sbjct: 933  EITTVSTTGSETTTASTEGSETTTA-----STEGSELTTVSTTGSETITVSAEGSETT-- 985

Query: 2177 SGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPT 2236
              + +++ +  TTAS + S     S A S T  A++     S  T  +     T TVS T
Sbjct: 986  --TVTTMGSETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTT 1040

Query: 2237 PSSHLASSTIAFPSTPRTTASTHTAPAF---SSQSTTSRSTSLTTRVPTSGFVSLTSGVT 2293
             +    +ST    +T  TTA + T   +   S  +TTS   S TT V T+G  + T+   
Sbjct: 1041 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1100

Query: 2294 GIPTSPVTNL---TTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCS 2350
             + T+ V+     TT         TT ++T S T   ST  S   +   T + T+    +
Sbjct: 1101 DLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTT 1160

Query: 2351 VREQQEEITFKGCMANVTVTRCEGACISAASFNIITQQVD 2390
              E     T       V+    E    SAA     T   +
Sbjct: 1161 GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1200



 Score =  267 bits (682), Expect = 1e-70
 Identities = 329/1197 (27%), Positives = 492/1197 (41%), Gaps = 132/1197 (11%)

Query: 1210 LPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSG 1269
            + T GS  T V  +TGT TT  ++S+ G   ++N T              TSS+ T +S 
Sbjct: 118  ISTAGSETTTV-SITGTETT--MVSAMGSETTTNST--------------TSSETTVTST 160

Query: 1270 EPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTM 1329
                 TT  T  + +    TA   +TA   T ++ TT  TA + +  T STA S T T  
Sbjct: 161  AGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSET-ITPSTAGSETTTVS 219

Query: 1330 T----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG--PTTPQPGQPTRP 1383
            T      T +T+G+  T   + + E   TTA  T G   T  ST G   T    G  T  
Sbjct: 220  TAGSETTTVSTTGSETTTASTAHSE---TTAASTMGSETTKVSTAGSETTVSTAGSETTA 276

Query: 1384 TATETTQTRTT-TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETT 1442
             +TE ++T T  TE +   T  TT    TA S   S  P  A++  + TT  +   PETT
Sbjct: 277  ASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE-PTMASTMGSETTMASTIGPETT 335

Query: 1443 LPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPI 1502
              +      T++    + T+           AS   + T      TT+  TGS  T   I
Sbjct: 336  KVSTASSEVTTVFAAGSETI----------RASTVGSET------TTVSTTGSETTTASI 379

Query: 1503 TPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTT---TITPNPTSTRTRTPVA 1559
              + + T     S +T  +     + T+ST   E T  STT   T T + T + T T   
Sbjct: 380  MGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCT 439

Query: 1560 HTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPF 1619
              +  T+       TT    T +S   S   + +TS   TTT  T     TT+ T     
Sbjct: 440  EGSEMTAVS-----TTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSET 494

Query: 1620 STSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTS 1679
             T+  T S  T  + T  +  T  +I S         TT    GS  TA + T +   T 
Sbjct: 495  KTAYTTGSETTTASNTGLETTTVFTIGS-------DTTTASTEGSETTAVSATGSEMTTV 547

Query: 1680 QALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS-TGTPPMTVTTSGTSQSRS 1738
                S NT  ++T   + T ST   E T+TST        S TG    T +T G+  + +
Sbjct: 548  STEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAA 607

Query: 1739 SFSTAKTST----SLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSAT-SSRL 1793
            S + ++T+T       + T+ST   E TS STT    + T+T + T    TT++T  S  
Sbjct: 608  STAGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEGSET 664

Query: 1794 PTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTH 1853
             T  TT S  T  +   S   +T+T    TTT  + +   TT+ T     +T  +T S  
Sbjct: 665  TTVSTTDSETTMVSTTGSERTITSTEGSETTTV-SATGSETTVSTEGSGTTTVSITGSET 723

Query: 1854 TVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAK 1913
            T +  T ++  T+++  S         TT   TGS  T      + + T+ +  S +T+ 
Sbjct: 724  TKVSTTGSETTTTSTEGS-------EITTASITGSETTTASTEGSETTTASTEGSETTSA 776

Query: 1914 TSTSLPYHTSSTHHPEVTPTSTTNITPKHTST-GTRTPVAHTTSASSSRLPTPFTTHSPP 1972
            ++T     T+ST   E T  S         ST G+ T      S +SS++ T FT +S  
Sbjct: 777  STTGSETTTASTTSSETTMASIMGSETTMASTIGSETT---KVSTASSKMTTVFTENSET 833

Query: 1973 TGSSPFSS-----------TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 2021
            T +S  +S           T P +    +TTTT  T     TT  T     +T+  T S+
Sbjct: 834  TIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE-TTTASTESS 892

Query: 2022 HTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSS---- 2077
             T   TT     T+AS   + T T     +   T ST  +   TV+T+G+  T +S    
Sbjct: 893  ETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGS 952

Query: 2078 -FSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPS 2136
              +TA+   S +++ S     + +       TT +  + S TT  ST    +++ S + S
Sbjct: 953  ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 1012

Query: 2137 APSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASP 2196
              +T      S   S  T+  S G+ ++ VS     TT++S   S  +T  T  S + + 
Sbjct: 1013 ETTTA-----SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1067

Query: 2197 LFPSSPAASTTIRATLPHTIS---SPFTLSALLPISTVTVSPTPSSHLASSTIAFPST-- 2251
                S   +T+   +   T+S   S  T ++   + T TVS + S    +ST    +T  
Sbjct: 1068 YTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1127

Query: 2252 -----PRTTASTH-----TAPAFSSQSTTSRST-----------SLTTRVPTSGFVSLTS 2290
                   TTAST      T    SS++TT+ +T           S TT V T G  + TS
Sbjct: 1128 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1187

Query: 2291 GVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPG 2347
               G   S  T  +T     T + T    T++ +  GS   +A  S   T T  + G
Sbjct: 1188 SAAG---SEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1241



 Score =  262 bits (670), Expect = 3e-69
 Identities = 327/1195 (27%), Positives = 485/1195 (40%), Gaps = 120/1195 (10%)

Query: 1207 TPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTA 1266
            T  + T GS  T  +     +T     S+TG   ++  T  S T TP    + T++  TA
Sbjct: 165  TTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSETTTVSTA 221

Query: 1267 SSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT--VTQATTRATASTASPATT--STAQ 1322
             S      TT       S      T  ST    T  V+ A +  T STA   TT  ST  
Sbjct: 222  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTED 281

Query: 1323 STTRTTMT----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPG 1378
            S T T  T      T +T+G   T   +T  E    T   T G   T AST GP T +  
Sbjct: 282  SETNTAFTEDSKTTTASTTGFETTAASTTGSE---PTMASTMGSETTMASTIGPETTKVS 338

Query: 1379 QPTRPTAT------ETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432
              +    T      ET +  T    TT  T  TT S  T  S + S     +T+   TTT
Sbjct: 339  TASSEVTTVFAAGSETIRASTVGSETT--TVSTTGSETTTASIMGSETSTDSTTGSETTT 396

Query: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTG---TIPPPTT 1489
              T     TT  T     +T   T S  T ++ T ++  T+ +  S  T    T+   TT
Sbjct: 397  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 456

Query: 1490 LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNP 1549
                GS  T    + + + T+    S +T  T     + T+ T   E T  S T +    
Sbjct: 457  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGL--ET 514

Query: 1550 TSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQ 1609
            T+  T      T S   S       T S  T  S   S     +T+   TTT  T     
Sbjct: 515  TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLET 574

Query: 1610 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAP 1669
            TT  T     +T + T    T    T     T+AS     T T+    +   T ST  + 
Sbjct: 575  TTTSTEGSEMTT-VSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 633

Query: 1670 TMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVT 1729
            T + +T+G+        T  ++TS  + T+ST  +E T+ STT+         +    V+
Sbjct: 634  TTSASTTGSE------TTTASTTSSETTTASTEGSETTTVSTTD---------SETTMVS 678

Query: 1730 TSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT----STGTRTPVAH- 1784
            T+G+ ++ +S   ++T+T   + + +T   E + T+T SIT + T    +TG+ T     
Sbjct: 679  TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST 738

Query: 1785 ------TTSATSSRLPTPFTTHSPPT-------GTTPISSTGPVTATSFQTT--TTYPTP 1829
                  T S T S   T  T  S  T        TT  S+TG  T T+  T+  TT  + 
Sbjct: 739  EGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI 798

Query: 1830 SHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGST 1889
                TT+ + + S +T + T S+    + T     T AS       T    TT  +T  +
Sbjct: 799  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS-------TTASETTTVSTAGS 851

Query: 1890 HTAPPMT---PTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPT------STTNITP 1940
             T P  T    TT+ TS   S  +TA T  S    T+ST   E T        +TT  T 
Sbjct: 852  ETIPASTAGSETTTTTSTEGSETTTASTEGS-ETTTASTESSETTTATTIGSETTTASTE 910

Query: 1941 KHTSTGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTP 1998
               +T T T  + TT+AS+  S + T  TT S  T +S   S     +T     TT  T 
Sbjct: 911  GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTT 970

Query: 1999 SH---------PQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP 2049
                        +TT  T +   +T+  T  + T  ++T     T+ASI  + T      
Sbjct: 971  GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET------ 1024

Query: 2050 TTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT 2109
            TT+ +TGS  T    TV+T+GT  T     T+T  S   + ++   + ++     S  TT
Sbjct: 1025 TTVSSTGSETT----TVSTTGTETT----ITSTEGSETTTVTTAGSETTAVYTTGSETTT 1076

Query: 2110 QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAP 2169
                  S TT VSTT   +++ S +    +TVS+   S   +   S+    T++ +++  
Sbjct: 1077 TSTE-GSETTTVSTTGSETTTASTADLETTTVST---SGSGTTTASTAGSETTTVYITGS 1132

Query: 2170 VHSTTLSSGSH----SSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSAL 2225
              +T  + GS     S+ S+  TTAS + S +   +   +T    T   TI S  T S+ 
Sbjct: 1133 KTTTASTEGSEATTVSTTSSETTTASTTGSEM---TTVFTTVSETTTVSTIGSEATTSSA 1189

Query: 2226 LPISTVTVSPTPSSHLASSTIAFPSTPRTTA--STHTAPAFSSQSTTSRSTSLTTRVPTS 2283
                  T S   S    +ST    +T  +TA   T TA    S++ T+ +T   T  P+S
Sbjct: 1190 AGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSS 1249

Query: 2284 -GFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSS 2337
             G  + T+ + G  T+ + +  +  P  T    +   T S+TA G+T AS  VSS
Sbjct: 1250 AGSETNTAFIIGSETT-IASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1303



 Score =  249 bits (637), Expect = 2e-65
 Identities = 293/1129 (25%), Positives = 473/1129 (41%), Gaps = 80/1129 (7%)

Query: 1205 PTTPQLPTTGSRPTQVWPM---TGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTS 1261
            P T ++ T  S  T V+     T  ++T+G  ++T  +  S  T AS   +     + T 
Sbjct: 332  PETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTG 391

Query: 1262 SKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTA 1321
            S+ T +S E    TTA    +T G   T T+ +T ++ T    T   T +T +  +  TA
Sbjct: 392  SETTTASTEGSETTTA----STEGSEAT-TVSTTGSETTTVSITDSETTTTCTEGSEMTA 446

Query: 1322 QSTTRTTMTLPTPATSGTSPTLPKSTNQELPG-------TTATQTTGPRPTPASTTGPTT 1374
             STT    T  T +T G+  T+  +++ E          TT   T G     A TTG  T
Sbjct: 447  VSTTVFETT--TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 504

Query: 1375 PQPGQPTRPTATETTQTRTTTEYTTPQTPHT----THSPPTAGSPVPSTGPVTATSFHAT 1430
                     T T  T    TT  +T  +  T    T S  T  S   S     +T+   T
Sbjct: 505  TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 564

Query: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTL 1490
            TT  T     TT  T      T++ T    T    T     T+AS   + T T+    + 
Sbjct: 565  TTVSTTGLETTTTSTEGSEM-TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 623

Query: 1491 KATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST----TTIT 1546
              T ST  +   + +T+G      S +T  + TS  + T+ST   E T  ST    TT+ 
Sbjct: 624  NTTASTADSETTSASTTG------SETTTASTTSSETTTASTEGSETTTVSTTDSETTMV 677

Query: 1547 PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMT----ATSFKTTTTY 1602
                S RT T    + + T S      T  +  +G++  S TG  T     T  +TTTT 
Sbjct: 678  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 737

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT---GTIPPPTTL 1659
               S  + T  +     +T+  T  + T    T     TSAS     T    T    TT+
Sbjct: 738  TEGS--EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 795

Query: 1660 KATGSTHT--APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPN 1717
             +   + T  A T+   T+  S A S + T  T  S  +  +ST  +E T+ ST      
Sbjct: 796  ASIMGSETTMASTIGSETTKVSTASSKMTTVFTENS-ETTIASTTASETTTVSTAGSETI 854

Query: 1718 PTSTGTPPMTVTTS--GTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTS 1775
            P ST     T TTS  G+  + +S   ++T+T+    + +T    + S +TT+ T    +
Sbjct: 855  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSET 914

Query: 1776 TGTRTPVAHTTSATS--SRLPTPFTTHS-PPTGTTPISSTGPVTATSFQTTTTYPTPSH- 1831
            T T T  + TT+A++  S + T  TT S   T +T  S T   +    + TT   T S  
Sbjct: 915  TTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 974

Query: 1832 -------PHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIK 1884
                     TT  T + S +T+  T  + T  + T     T+ASI    T      TT+ 
Sbjct: 975  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET------TTVS 1028

Query: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944
            +TGS  T    T +T+GT  + +S   ++T+T     + +T        +TT  T    +
Sbjct: 1029 STGSETT----TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSET 1084

Query: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT---TTTYPTPSHP 2001
            T   T  + TT+AS++ L T  T  +  +G++  S+ G  T T + T   TTT  T    
Sbjct: 1085 TTVSTTGSETTTASTADLETT-TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSE 1143

Query: 2002 QTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS---TPTGTVPPPTTLKATGST 2058
             TT+ T     +T+  T S  T + TT ++  T ++I S   T +      TT    GS 
Sbjct: 1144 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1203

Query: 2059 HTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSAT 2118
             T      + + T+ T  S +T  ++S   ++++    + +S P S+   T    +  + 
Sbjct: 1204 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSE 1263

Query: 2119 TPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSG 2178
            T +++T    +S  P+ ++ +   +   S  +S  T++ +  +S++FV       ++   
Sbjct: 1264 TTIAST----ASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI 1319

Query: 2179 SHSSLS-THPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTP 2237
            +++ +S T  T   ++AS     +P    T  A   HT+      ++ L  ST+  S T 
Sbjct: 1320 TNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAA-SHTVPGIVLNTSGLGTSTMGASSTT 1378

Query: 2238 SSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFV 2286
            S+H   +T      P ++    T P     +T S S + T  +  SG++
Sbjct: 1379 SAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSGYL 1427



 Score =  247 bits (630), Expect = 1e-64
 Identities = 314/1141 (27%), Positives = 471/1141 (41%), Gaps = 113/1141 (9%)

Query: 1259 LTSSKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATT 1318
            +  S+ T +S    +  TA +  + + + P A   +T T  T    TT      +   T 
Sbjct: 1    MAGSEATTTSTADSKVITASSMSSETTVAPAAG-SNTTTASTTGSETTTILIKASETTTA 59

Query: 1319 STAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPG 1378
            STA S T T      P+ +G+  T+   +  E+   T T T G   T  S+ G  T    
Sbjct: 60   STAGSETTT------PSPTGSQTTIVSISGSEI---TTTSTAGSENTTVSSAGSGTTTAS 110

Query: 1379 QPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSH 1438
                 +   T  + TT       T   T +  T  S + S     +T+   TT   T   
Sbjct: 111  MAGSESTISTAGSETT-------TVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGS 163

Query: 1439 PETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHT 1498
              TT+ T     +T+    S  T  + T ++M T     +A + TI P T    T +  T
Sbjct: 164  ETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV---FTAGSETITPSTAGSETTTVST 220

Query: 1499 APPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTI-TPNPTSTRTRTP 1557
            A   T T S T    ++ ST  + T+  S   S      T  S TT+ T    +T   T 
Sbjct: 221  AGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE 280

Query: 1558 VAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHP--------Q 1609
             + TN+A        FT  S  T +S          T F+TT    T S P        +
Sbjct: 281  DSETNTA--------FTEDSKTTTAS---------TTGFETTAASTTGSEPTMASTMGSE 323

Query: 1610 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGS-THTA 1668
            TT+ + + P +T + T S+      T    A S +I +   G+    TT+  TGS T TA
Sbjct: 324  TTMASTIGPETTKVSTASSEV----TTVFAAGSETIRASTVGS--ETTTVSTTGSETTTA 377

Query: 1669 PTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTV 1728
              M   TS  S   S   TA T  S  + T+ST  +EAT+ STT      + T T  +T 
Sbjct: 378  SIMGSETSTDSTTGSETTTASTEGS-ETTTASTEGSEATTVSTTG-----SETTTVSITD 431

Query: 1729 TTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTT-SITPNHTSTGTRTPVAHTTS 1787
            + + T+ +  S  TA ++T   + T+ST   E+T  ST+ S T   ++ G+ T    T +
Sbjct: 432  SETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETT---TVT 488

Query: 1788 ATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQ--TTTTYPTPSHPHTTLPTHVPSFST 1845
               S   T +TT S    TT  S+TG  T T F   + TT  +     TT  +   S  T
Sbjct: 489  TAGSETKTAYTTGSE---TTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMT 545

Query: 1846 SLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQS 1905
            ++ T  +    + T     T+ S   + T T     +   T ST  A   T +T G+  +
Sbjct: 546  TVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTT 605

Query: 1906 PSSFSTAKTST----SLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSR 1961
             +S + ++T+T         T+ST   E T  STT    + T+  T +    T S   S 
Sbjct: 606  AASTAGSETTTVSTADSENTTASTADSETTSASTTG--SETTTASTTSSETTTASTEGSE 663

Query: 1962 LPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPST 2021
              T  TT S  T  S   S   +T+T    TTT  + +  +TT+ T     +T  +T S 
Sbjct: 664  TTTVSTTDSETTMVSTTGSERTITSTEGSETTTV-SATGSETTVSTEGSGTTTVSITGSE 722

Query: 2022 HTVIITTHTQMATSASIHS---TPTGTVPPPTTLKATGS-THTAPPMTVTTSGTSQTHSS 2077
             T + TT ++  T+++  S   T + T    TT    GS T TA      T+  S T S 
Sbjct: 723  TTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSE 782

Query: 2078 FSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSA 2137
             +TA+ +SS  + +S +   ++        TT++   SS  T V T N  ++  S + S 
Sbjct: 783  TTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASE 842

Query: 2138 PSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPL 2197
             +TVS+    S + P +++ S  T          +TT + GS +      TTAS   S  
Sbjct: 843  TTTVST--AGSETIPASTAGSETT----------TTTSTEGSET------TTASTEGSET 884

Query: 2198 FPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSSHLASSTIAFP-STPRTTA 2256
              +S  +S T  AT   TI S  T ++     T T S   S    +ST     +T  TT 
Sbjct: 885  TTASTESSETTTAT---TIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTG 941

Query: 2257 STHTAPAFSSQSTTSRST--SLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSP 2314
            S  T  +     TT+ ST  S  T V T+G  ++T    G   S  T +TT     T + 
Sbjct: 942  SETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG---SETTTVTTMGSETTTAS 998

Query: 2315 TTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVREQQEEITFKGCMANVTVTRCEG 2374
            T    T++++  GS   +A +    T T +S G        E  T        T+T  EG
Sbjct: 999  TAGSETTTVSTAGSETTTASIEGSETTTVSSTG-------SETTTVSTTGTETTITSTEG 1051

Query: 2375 A 2375
            +
Sbjct: 1052 S 1052



 Score =  229 bits (585), Expect = 2e-59
 Identities = 296/1102 (26%), Positives = 452/1102 (41%), Gaps = 158/1102 (14%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTI---GLLSSTGPSPSSNHTPASPTQTPLLP 1256
            TT    T  +  TT +  ++   MT  STT+      S+ G   +   T  S T T    
Sbjct: 424  TTTVSITDSETTTTCTEGSE---MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTE 480

Query: 1257 ATLTSSKPTASSGEPPRPTTA--VTPQATSGLPPTA--TLRSTATKPTVTQATTRATAST 1312
             + T++  TA S      TT    T  + +GL  T   T+ S  T  +   + T A ++T
Sbjct: 481  GSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 540

Query: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372
             S  TT + + +  TT++     T+G+  T   +T  E   TT T T G   T  STTG 
Sbjct: 541  GSEMTTVSTEGSENTTVS-----TTGSETTTVSTTGLE---TTTTSTEGSEMTTVSTTGA 592

Query: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432
             T         T   +T    TT  +T  + +TT S  TA S   S     +T+   TTT
Sbjct: 593  ETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS--TADSETTSA----STTGSETTT 646

Query: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKA 1492
              T S   TT  T     +T   T S  T+++ T ++   +++  S  T       T+ A
Sbjct: 647  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT-------TVSA 699

Query: 1493 TGSTHTAPPITPTTSGTSQAH--SSFSTNKTPTSLHSHTSSTHHPEVTPTS------TTT 1544
            TGS  T   ++   SGT+      S +T  + T   + T+ST   E+T  S      TT 
Sbjct: 700  TGSETT---VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 756

Query: 1545 ITPNPTSTRTRTPVAHTNSA--TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTY 1602
             T    +T   T  + T SA  T S      TT S  T +S   S   M +T    TT  
Sbjct: 757  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 816

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKAT 1662
             T S   TT+ T     + +  T S  T ++        +A   ++P  T    TT   T
Sbjct: 817  STASSKMTTVFTENSETTIASTTASETTTVS--------TAGSETIPASTAGSETT--TT 866

Query: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSL----HSHTSSTHHAEATSTSTTNITPNP 1718
             ST  + T T +T G+    +S  +++T+T+      + T+ST  +E T+TST       
Sbjct: 867  TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 926

Query: 1719 TST-GTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTT---------- 1767
             ST G+   TV+T+G+  + +S   ++T+T+      ST   E+T+ STT          
Sbjct: 927  ASTEGSEITTVSTTGSETTTASTEGSETTTA------STEGSELTTVSTTGSETITVSAE 980

Query: 1768 -SITPNHTSTGTRTPVAHTTSATSSRLPTPF--TTHSPPTG--TTPISSTGPVTAT--SF 1820
             S T   T+ G+ T  A T  + ++ + T    TT +   G  TT +SSTG  T T  + 
Sbjct: 981  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1040

Query: 1821 QTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPP 1880
             T TT  +     TT  T   S +T++ T  + T    T     T+ S     T T    
Sbjct: 1041 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1100

Query: 1881 ----TTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTT 1936
                TT+  +GS  T    T +T+G+  +    + +KT+      T+ST   E T  STT
Sbjct: 1101 DLETTTVSTSGSGTT----TASTAGSETTTVYITGSKTT------TASTEGSEATTVSTT 1150

Query: 1937 NITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYP 1996
            +         + T  A TT    S + T FTT S  T  S   S    ++ +    TT  
Sbjct: 1151 S---------SETTTASTT---GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTS 1198

Query: 1997 TPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056
            T     TT                            A++A   +T   T    TT  +T 
Sbjct: 1199 TEGSETTT----------------------------ASTAGSETTTASTAGSETTTASTS 1230

Query: 2057 STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS 2116
             + T      TT   + T SS  + T ++  I S + +   +S  P ++ +T       S
Sbjct: 1231 GSET--NTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT------GS 1282

Query: 2117 ATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT---------SSSFVS 2167
             TT VS T   +++ S + S+ + V +        P T++P  GT         SSS   
Sbjct: 1283 ETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTM 1342

Query: 2168 APVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHT---ISSPF--TL 2222
            AP    T S+ SH+       T+ +  S +  SS  ++  +R T   T    SS F  T 
Sbjct: 1343 APGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETG 1402

Query: 2223 SALLPISTVTVSPTPSSHLASS 2244
               +  +TV++S TP++ +  S
Sbjct: 1403 PVSMGTNTVSMSHTPTNVIKPS 1424



 Score =  130 bits (326), Expect = 2e-29
 Identities = 165/597 (27%), Positives = 231/597 (38%), Gaps = 73/597 (12%)

Query: 1197 MPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256
            +P +T    TT    T GS  T       T++T G  ++T  + SS  T A+   +    
Sbjct: 854  IPASTAGSETTTTTSTEGSETT-------TASTEGSETTTASTESSETTTATTIGSETTT 906

Query: 1257 ATLTSSKPTASSGEPPRPTTA-------VTPQATSGLPPTATLRSTATKPTVTQATTRAT 1309
            A+   S+ T +S E    TTA        T   T     TA+   + T    T+ +   T
Sbjct: 907  ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT 966

Query: 1310 ASTASPATTSTA----QSTTRTTM--TLPTPATSGTSPTLPKSTNQELPGTTATQTTGPR 1363
             ST    T + +    ++TT TTM     T +T+G+  T   +   E   TT     G  
Sbjct: 967  VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE---TTTASIEGSE 1023

Query: 1364 PTPASTTGPTTPQPGQPTRPTATETTQT---------------RTTTEYTTPQTPHTTHS 1408
             T  S+TG  T         T TETT T                TT  YTT     TT +
Sbjct: 1024 TTTVSSTGSETTT----VSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1079

Query: 1409 PPTAGSPVPSTGPVTATSFHA---TTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITP 1465
              +  + V +TG  T T+  A   TTT  T     TT  T     +T  +T S  T    
Sbjct: 1080 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS-KTTTAS 1138

Query: 1466 THAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSL 1525
            T    AT+ S  S+ T      TT   TGS  T    T + + T     S +T  +    
Sbjct: 1139 TEGSEATTVSTTSSET------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGS 1192

Query: 1526 HSHTSSTHHPEVTPTS------TTTITPNPTSTRTRTPVAHTNSA--TSSRPPPPFTTHS 1577
             + T+ST   E T  S      TT  T    +T   T  + TN+A  T S    P +  S
Sbjct: 1193 EATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGS 1252

Query: 1578 PPTGSSPFSSTGPMTAT-SFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTH 1636
                +    S   + +T S + T T  T S   T   T     + S    ST  V+T   
Sbjct: 1253 ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLT--- 1309

Query: 1637 AQMATSASIHSMP----TGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSS--LNTAKT 1690
               AT  SI  +     +GT    T L A+ S   AP M  T S  S  +    LNT+  
Sbjct: 1310 --KATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGL 1367

Query: 1691 STSLHSHTSSTH-HAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS 1746
             TS    +S+T  H   T+T +T    + T   T P+++ T+  S S +  +  K S
Sbjct: 1368 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPS 1424


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  276 bits (707), Expect = 1e-73
 Identities = 340/1237 (27%), Positives = 510/1237 (41%), Gaps = 120/1237 (9%)

Query: 1215 SRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEP-PR 1273
            S  T V P  G++TT    S+TG          S T T L+ A+ T++  TA S    P 
Sbjct: 2    SSETTVAPAAGSNTTTA--STTG----------SETTTILIKASETTTASTAGSETTTPS 49

Query: 1274 PT-----------TAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQ 1322
            PT           + +T  +T+G   T    + +   T + A +  T STA   TT+ + 
Sbjct: 50   PTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI 109

Query: 1323 STTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP-TTPQPGQPT 1381
            + T TTM     +  G+  T   +T+ E   TT T T G   T  ST G  TT      +
Sbjct: 110  TGTETTMV----SAMGSETTTNSTTSSE---TTVTSTAGSETTTVSTVGSETTTAYTADS 162

Query: 1382 RPTATETTQTRTTTEYTTPQ---TPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSH 1438
              TA  TT +  TT +T      TP T  S  T  S   S     +T+   TTT  T +H
Sbjct: 163  ETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST-AH 221

Query: 1439 PETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTI----PPPTTLKATG 1494
             ETT  + +   +T + T  + T ++ T     T+AS   + T T        TT   TG
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVS-TAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 1495 STHTAPPIT---PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551
               TA   T   PT + T  + ++ ++   P +    T+S+    V    + TI  +   
Sbjct: 281  FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 1552 TRTRTPVAHTNSATS------SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTP 1605
            + T T V+ T S T+      S      TT S  T +S   S     +T     TT  T 
Sbjct: 341  SETTT-VSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTT 399

Query: 1606 SHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT--GTIPPPTTLKATG 1663
                TT+       +T+    S  T ++ T  +  T+++  S  T   T    TT   T 
Sbjct: 400  GSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT---TA 456

Query: 1664 STHTAPTMTLTTSG----TSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI-TPNP 1718
            ST  + T T+TT+G    T+    S  T  ++T L + T  T  ++ T+ ST    T   
Sbjct: 457  STEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV 516

Query: 1719 TSTGTPPMTVTTSG----TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT 1774
            ++TG+   TV+T G    T  +  S +T  ++T L + T+ST   E+T+ STT       
Sbjct: 517  SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTD 576

Query: 1775 ST-GTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPH 1833
            ST G+ T  A T  + ++ + T  + ++  T +T  S T   + T  +TTT   T S   
Sbjct: 577  STEGSGTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSE-- 632

Query: 1834 TTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAP 1893
            TT  +   S +T++ T  + T ++ T     T  S     T      TT+ ATGS  T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET------TTVSATGSETTVS 686

Query: 1894 PM---TPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTS------TTNITPKHTS 1944
                 T T S T    +  ST  + T+    T+ST   E+T  S      TT  T    +
Sbjct: 687  TEGSGTTTVSITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSET 742

Query: 1945 TGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ 2002
            T   T  + TTSAS+  S   T  TT S  T +S   S   M +T    TT   T S   
Sbjct: 743  TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802

Query: 2003 TTLPTHVPPFSTSLVTPSTHTVIITTHTQ---MATSASIHSTPTGTVPPPTTLKATGSTH 2059
            TT+ T     + +  T S  T + T  ++    +T+ S  +T T T    TT  +T  + 
Sbjct: 803  TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862

Query: 2060 TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT 2119
            T    T ++  T+ T     T TAS+    +++   + S         TT      S  T
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSE--------TTTASTEGSEIT 914

Query: 2120 PVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGS 2179
             VSTT   +++ S   S  +T      S+  S  T+  + G+ +  VSA    TT    +
Sbjct: 915  TVSTTGSETTTASTEGSETTTA-----STEGSELTTVSTTGSETITVSAEGSETT----T 965

Query: 2180 HSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSS 2239
             +++ +  TTAS + S     S A S T  A++     S  T  +     T TVS T + 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTE 1022

Query: 2240 HLASSTIAFPSTPRTTASTHTAPAF---SSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP 2296
               +ST    +T  TTA + T   +   S  +TTS   S TT V T+G  + T+    + 
Sbjct: 1023 TTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLE 1082

Query: 2297 TSPVTNL---TTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVRE 2353
            T+ V+     TT         TT ++T S T   ST  S   +   T + T+    +  E
Sbjct: 1083 TTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142

Query: 2354 QQEEITFKGCMANVTVTRCEGACISAASFNIITQQVD 2390
                 T       V+    E    SAA     T   +
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179



 Score =  266 bits (679), Expect = 2e-70
 Identities = 331/1233 (26%), Positives = 496/1233 (40%), Gaps = 139/1233 (11%)

Query: 1207 TPQLPTTGSRPTQVWPMTGTSTTIGLLS----STGPSPSSNHTPASPTQTPLLPATLTSS 1262
            T    T GS  T   P TG+ TTI  +S    +T  +  S +T  S   +    A++  S
Sbjct: 35   TTTASTAGSETTTPSP-TGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 1263 KPTASSGEPPRPTTAVTPQATSGLPP----TATLRSTATKPTVTQ--ATTRATASTASPA 1316
            + T S+      T ++T   T+ +      T T  +T+++ TVT    +   T ST    
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE 153

Query: 1317 TT--------STAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPAS 1368
            TT        +TA STT + MT  T  T+G+    P +   E   TT   T G   T  S
Sbjct: 154  TTTAYTADSETTAASTTGSEMT--TVFTAGSETITPSTAGSE---TTTVSTAGSETTTVS 208

Query: 1369 TTGPTTPQPGQPTRPTATETTQTRTTTEYTT---PQTPHTTHSPPTAGSPVPS------- 1418
            TTG  T         T   +T    TT+ +T     T  T  S  TA S   S       
Sbjct: 209  TTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFT 268

Query: 1419 ----TGPVTATSFHATTTYPTPSHP--------ETTLPTHVPPFSTSLVTPSTHTVITPT 1466
                T   + T F  T    T S P        ETT+ + + P +T + T S+       
Sbjct: 269  EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFA 328

Query: 1467 HAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLH 1526
                   AS   + T      TT+  TGS  T   I  + + T     S +T  +     
Sbjct: 329  AGSETIRASTVGSET------TTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSE 382

Query: 1527 SHTSSTHHPEVTPTSTT---TITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS 1583
            + T+ST   E T  STT   T T + T + T T     +  T+       TT    T +S
Sbjct: 383  TTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVS-----TTVFETTTAS 437

Query: 1584 PFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSA 1643
               S   + +TS   TTT  T     TT+ T      T+  T S  T  + T  +  T  
Sbjct: 438  TEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVF 497

Query: 1644 SIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHH 1703
            +I S         TT    GS  TA + T +   T     S NT  ++T   + T ST  
Sbjct: 498  TIGS-------DTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG 550

Query: 1704 AEATSTSTTNITPNPTS-TGTPPMTVTTSGTSQSRSSFSTAKTST----SLHSHTSSTHH 1758
             E T+TST        S TG    T +T G+  + +S + ++T+T       + T+ST  
Sbjct: 551  LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTAD 610

Query: 1759 PEVTSTSTTSITPNHTSTGTRTPVAHTTSAT-SSRLPTPFTTHSPPTGTTPISSTGPVTA 1817
             E TS STT    + T+T + T    TT++T  S   T  TT S  T  +   S   +T+
Sbjct: 611  SETTSASTTG---SETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITS 667

Query: 1818 TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI 1877
            T    TTT  + +   TT+ T     +T  +T S  T +  T ++  T+++  S      
Sbjct: 668  TEGSETTTV-SATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGS------ 720

Query: 1878 PPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTN 1937
               TT   TGS  T      + + T+ +  S +T+ ++T     T+ST   E T  S   
Sbjct: 721  -EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 1938 ITPKHTST-GTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS-----------TGPMT 1985
                  ST G+ T      S +SS++ T FT +S  T +S  +S           T P +
Sbjct: 780  SETTMASTIGSETT---KVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS 836

Query: 1986 ATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGT 2045
                +TTTT  T     TT  T     +T+  T S+ T   TT     T+AS   + T T
Sbjct: 837  TAGSETTTTTSTEGSETTTASTEGSE-TTTASTESSETTTATTIGSETTTASTEGSETTT 895

Query: 2046 VPPPTTLKATGSTHTAPPMTVTTSGTSQTHSS-----FSTATASSSFISSSSWLPQNSSS 2100
                 +   T ST  +   TV+T+G+  T +S      +TA+   S +++ S     + +
Sbjct: 896  TSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETIT 955

Query: 2101 RPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVG 2160
                   TT +  + S TT  ST    +++ S + S  +T      S   S  T+  S G
Sbjct: 956  VSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTA-----SIEGSETTTVSSTG 1010

Query: 2161 TSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTIS--- 2217
            + ++ VS     TT++S   S  +T  T  S + +     S   +T+   +   T+S   
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 2218 SPFTLSALLPISTVTVSPTPSSHLASSTIAFPST-------PRTTASTH-----TAPAFS 2265
            S  T ++   + T TVS + S    +ST    +T         TTAST      T    S
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 2266 SQSTTSRST-----------SLTTRVPTSGFVSLTSGVTGIPTSPVTNLTTRHPGPTLSP 2314
            S++TT+ +T           S TT V T G  + TS   G   S  T  +T     T + 
Sbjct: 1131 SETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAG---SEATTTSTEGSETTTAS 1187

Query: 2315 TTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPG 2347
            T    T++ +  GS   +A  +   T T ++ G
Sbjct: 1188 TAGSETTTASTAGSETTTASTAGSETTTASTSG 1220



 Score =  261 bits (668), Expect = 5e-69
 Identities = 331/1204 (27%), Positives = 485/1204 (40%), Gaps = 128/1204 (10%)

Query: 1207 TPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTA 1266
            T  + T GS  T  +     +T     S+TG   ++  T  S T TP    + T++  TA
Sbjct: 144  TTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1267 SSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT--VTQATTRATASTASPATT--STAQ 1322
             S      TT       S      T  ST    T  V+ A +  T STA   TT  ST  
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTED 260

Query: 1323 STTRTTMT----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPG 1378
            S T T  T      T +T+G   T   +T  E    T   T G   T AST GP T +  
Sbjct: 261  SETNTAFTEDSKTTTASTTGFETTAASTTGSE---PTMASTMGSETTMASTIGPETTKVS 317

Query: 1379 QPTRPTAT------ETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432
              +    T      ET +  T    TT  T  TT S  T  S + S     +T+   TTT
Sbjct: 318  TASSEVTTVFAAGSETIRASTVGSETT--TVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTG---TIPPPTT 1489
              T     TT  T     +T   T S  T ++ T ++  T+ +  S  T    T+   TT
Sbjct: 376  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 1490 LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNP 1549
                GS  T    + + + T+    S +T  T     + T+ T   E T  S T +    
Sbjct: 436  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGL--ET 493

Query: 1550 TSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQ 1609
            T+  T      T S   S       T S  T  S   S     +T+   TTT  T     
Sbjct: 494  TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLET 553

Query: 1610 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAP 1669
            TT  T     +T + T    T    T     T+AS     T T+    +   T ST  + 
Sbjct: 554  TTTSTEGSEMTT-VSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 1670 TMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVT 1729
            T + +T+G+        T  ++TS  + T+ST  +E T+ STT+         +    V+
Sbjct: 613  TTSASTTGSE------TTTASTTSSETTTASTEGSETTTVSTTD---------SETTMVS 657

Query: 1730 TSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT----STGTRTPVAH- 1784
            T+G+ ++ +S   ++T+T   + + +T   E + T+T SIT + T    +TG+ T     
Sbjct: 658  TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST 717

Query: 1785 ------TTSATSSRLPTPFTTHSPPT-------GTTPISSTGPVTATSFQTT--TTYPTP 1829
                  T S T S   T  T  S  T        TT  S+TG  T T+  T+  TT  + 
Sbjct: 718  EGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 1830 SHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGST 1889
                TT+ + + S +T + T S+    + T     T AS       T    TT  +T  +
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS-------TTASETTTVSTAGS 830

Query: 1890 HTAPPMT---PTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPT------STTNITP 1940
             T P  T    TT+ TS   S  +TA T  S    T+ST   E T        +TT  T 
Sbjct: 831  ETIPASTAGSETTTTTSTEGSETTTASTEGS-ETTTASTESSETTTATTIGSETTTASTE 889

Query: 1941 KHTSTGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTP 1998
               +T T T  + TT+AS+  S + T  TT S  T +S   S     +T     TT  T 
Sbjct: 890  GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTT 949

Query: 1999 SH---------PQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP 2049
                        +TT  T +   +T+  T  + T  ++T     T+ASI  + T      
Sbjct: 950  GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET------ 1003

Query: 2050 TTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT 2109
            TT+ +TGS  T    TV+T+GT  T     T+T  S   + ++   + ++     S  TT
Sbjct: 1004 TTVSSTGSETT----TVSTTGTETT----ITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055

Query: 2110 QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAP 2169
                  S TT VSTT   +++ S +    +TVS+   S   +   S+    T++ +++  
Sbjct: 1056 TSTE-GSETTTVSTTGSETTTASTADLETTTVST---SGSGTTTASTAGSETTTVYITGS 1111

Query: 2170 VHSTTLSSGSH----SSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSAL 2225
              +T  + GS     S+ S+  TTAS + S +   +   +T    T   TI S  T S+ 
Sbjct: 1112 KTTTASTEGSEATTVSTTSSETTTASTTGSEM---TTVFTTVSETTTVSTIGSEATTSSA 1168

Query: 2226 LPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHT---APAFSSQSTTSRSTSLTTRVPT 2282
                  T S   S    +ST    +T  +TA + T   + A S  +T S S S T    T
Sbjct: 1169 AGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACT 1228

Query: 2283 SGFVSLTSGVTGIPTSP---VTNLTTRHPGPTLSPTTRFLTS------SLTAHGSTPASA 2333
            +G  + T    G  T+    + + TT     +L PT   LT       S+TA G+T AS 
Sbjct: 1229 TGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAAST 1288

Query: 2334 PVSS 2337
             VSS
Sbjct: 1289 TVSS 1292



 Score =  250 bits (638), Expect = 1e-65
 Identities = 302/1140 (26%), Positives = 474/1140 (41%), Gaps = 92/1140 (8%)

Query: 1205 PTTPQLPTTGSRPTQVWPM---TGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTS 1261
            P T ++ T  S  T V+     T  ++T+G  ++T  +  S  T AS   +     + T 
Sbjct: 311  PETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTG 370

Query: 1262 SKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTA 1321
            S+ T +S E    TTA    +T G   T T+ +T ++ T    T   T +T +  +  TA
Sbjct: 371  SETTTASTEGSETTTA----STEGSEAT-TVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 1322 QSTTRTTMTLPTPATSGTSPTLPKSTNQELPG-------TTATQTTGPRPTPASTTGPTT 1374
             STT    T  T +T G+  T+  +++ E          TT   T G     A TTG  T
Sbjct: 426  VSTTVFETT--TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 483

Query: 1375 PQPGQPTRPTATETTQTRTTTEYTTPQTPHT----THSPPTAGSPVPSTGPVTATSFHAT 1430
                     T T  T    TT  +T  +  T    T S  T  S   S     +T+   T
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTL 1490
            TT  T     TT  T      T++ T    T    T     T+AS   + T T+    + 
Sbjct: 544  TTVSTTGLETTTTSTEGSEM-TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602

Query: 1491 KATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST----TTIT 1546
              T ST  +   + +T+G      S +T  + TS  + T+ST   E T  ST    TT+ 
Sbjct: 603  NTTASTADSETTSASTTG------SETTTASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 1547 PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMT----ATSFKTTTTY 1602
                S RT T    + + T S      T  +  +G++  S TG  T     T  +TTTT 
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT---GTIPPPTTL 1659
               S  + T  +     +T+  T  + T    T     TSAS     T    T    TT+
Sbjct: 717  TEGS--EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 774

Query: 1660 KATGSTHT--APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPN 1717
             +   + T  A T+   T+  S A S + T  T  S  +  +ST  +E T+ ST      
Sbjct: 775  ASIMGSETTMASTIGSETTKVSTASSKMTTVFTENS-ETTIASTTASETTTVSTAGSETI 833

Query: 1718 PTSTGTPPMTVTTS--GTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTS 1775
            P ST     T TTS  G+  + +S   ++T+T+    + +T    + S +TT+ T    +
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSET 893

Query: 1776 TGTRTPVAHTTSATS--SRLPTPFTTHS-PPTGTTPISSTGPVTATSFQTTTTYPTPSH- 1831
            T T T  + TT+A++  S + T  TT S   T +T  S T   +    + TT   T S  
Sbjct: 894  TTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 953

Query: 1832 -------PHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIK 1884
                     TT  T + S +T+  T  + T  + T     T+ASI    T      TT+ 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET------TTVS 1007

Query: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944
            +TGS  T    T +T+GT  + +S   ++T+T     + +T        +TT  T    +
Sbjct: 1008 STGSETT----TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSET 1063

Query: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT---TTTYPTPSHP 2001
            T   T  + TT+AS++ L T  T  +  +G++  S+ G  T T + T   TTT  T    
Sbjct: 1064 TTVSTTGSETTTASTADLETT-TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122

Query: 2002 QTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS------------TPTGTVPPP 2049
             TT+ T     +T+  T S  T + TT ++  T ++I S            T T T    
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182

Query: 2050 TTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSS--PI 2107
            TT  +T  + T    T  +  T+ + +   T TAS+S   +++     S +  PSS    
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE 1242

Query: 2108 TTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVS 2167
            T     + S TT  ST +   ++ S + S  +TV     S  +S  T++ +  +S++FV 
Sbjct: 1243 TNTAFIIGSETTIASTASLEPTATSLTGSETTTV-----SITASGATAASTTVSSTTFVL 1297

Query: 2168 APVHSTTLSSGSHSSLS-THPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALL 2226
                  ++   +++ +S T  T   ++AS     +P    T  A   HT+      ++ L
Sbjct: 1298 TKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAA-SHTVPGIVLNTSGL 1356

Query: 2227 PISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFV 2286
              ST+  S T S+H   +T      P ++    T P     +T S S + T  +  SG++
Sbjct: 1357 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSGYL 1416



 Score =  235 bits (599), Expect = 5e-61
 Identities = 298/1102 (27%), Positives = 455/1102 (41%), Gaps = 148/1102 (13%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTI---GLLSSTGPSPSSNHTPASPTQTPLLP 1256
            TT    T  +  TT +  ++   MT  STT+      S+ G   +   T  S T T    
Sbjct: 403  TTTVSITDSETTTTCTEGSE---MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTE 459

Query: 1257 ATLTSSKPTASSGEPPRPTTA--VTPQATSGLPPTA--TLRSTATKPTVTQATTRATAST 1312
             + T++  TA S      TT    T  + +GL  T   T+ S  T  +   + T A ++T
Sbjct: 460  GSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519

Query: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372
             S  TT + + +  TT++     T+G+  T   +T  E   TT T T G   T  STTG 
Sbjct: 520  GSEMTTVSTEGSENTTVS-----TTGSETTTVSTTGLE---TTTTSTEGSEMTTVSTTGA 571

Query: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432
             T         T   +T    TT  +T  + +TT S  TA S   S     +T+   TTT
Sbjct: 572  ETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS--TADSETTSA----STTGSETTT 625

Query: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKA 1492
              T S   TT  T     +T   T S  T+++ T ++   +++  S  T       T+ A
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT-------TVSA 678

Query: 1493 TGSTHTAPPITPTTSGTSQAH--SSFSTNKTPTSLHSHTSSTHHPEVTPTS------TTT 1544
            TGS  T   ++   SGT+      S +T  + T   + T+ST   E+T  S      TT 
Sbjct: 679  TGSETT---VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 1545 ITPNPTSTRTRTPVAHTNSA--TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTY 1602
             T    +T   T  + T SA  T S      TT S  T +S   S   M +T    TT  
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKAT 1662
             T S   TT+ T     + +  T S  T ++        +A   ++P  T    TT   T
Sbjct: 796  STASSKMTTVFTENSETTIASTTASETTTVS--------TAGSETIPASTAGSETT--TT 845

Query: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSL----HSHTSSTHHAEATSTSTTNITPNP 1718
             ST  + T T +T G+    +S  +++T+T+      + T+ST  +E T+TST       
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 1719 TST-GTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTT---------- 1767
             ST G+   TV+T+G+  + +S   ++T+T+      ST   E+T+ STT          
Sbjct: 906  ASTEGSEITTVSTTGSETTTASTEGSETTTA------STEGSELTTVSTTGSETITVSAE 959

Query: 1768 -SITPNHTSTGTRTPVAHTTSATSSRLPTPF--TTHSPPTG--TTPISSTGPVTAT--SF 1820
             S T   T+ G+ T  A T  + ++ + T    TT +   G  TT +SSTG  T T  + 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1821 QTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPP 1880
             T TT  +     TT  T   S +T++ T  + T    T     T+ S     T T    
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079

Query: 1881 ----TTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTT 1936
                TT+  +GS  T    T +T+G+  +    + +KT+      T+ST   E T  STT
Sbjct: 1080 DLETTTVSTSGSGTT----TASTAGSETTTVYITGSKTT------TASTEGSEATTVSTT 1129

Query: 1937 NITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYP 1996
            +         + T  A TT    S + T FTT S  T  S   S    ++ +    TT  
Sbjct: 1130 S---------SETTTASTT---GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTS 1177

Query: 1997 TPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056
            T     TT  T                    + T  A++A   +T   T    TT  +T 
Sbjct: 1178 TEGSETTTAST------------------AGSETTTASTAGSETTTASTAGSETTTASTS 1219

Query: 2057 STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS 2116
             + T      TT   + T SS  + T ++  I S + +   +S  P ++ +T       S
Sbjct: 1220 GSET--NTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT------GS 1271

Query: 2117 ATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT---------SSSFVS 2167
             TT VS T   +++ S + S+ + V +        P T++P  GT         SSS   
Sbjct: 1272 ETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTM 1331

Query: 2168 APVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHT---ISSPF--TL 2222
            AP    T S+ SH+       T+ +  S +  SS  ++  +R T   T    SS F  T 
Sbjct: 1332 APGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETG 1391

Query: 2223 SALLPISTVTVSPTPSSHLASS 2244
               +  +TV++S TP++ +  S
Sbjct: 1392 PVSMGTNTVSMSHTPTNVIKPS 1413



 Score =  130 bits (326), Expect = 2e-29
 Identities = 170/641 (26%), Positives = 250/641 (39%), Gaps = 84/641 (13%)

Query: 1197 MPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256
            +P +T    TT    T GS  T       T++T G  ++T  + SS  T A+   +    
Sbjct: 833  IPASTAGSETTTTTSTEGSETT-------TASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 1257 ATLTSSKPTASSGEPPRPTTA-------VTPQATSGLPPTATLRSTATKPTVTQATTRAT 1309
            A+   S+ T +S E    TTA        T   T     TA+   + T    T+ +   T
Sbjct: 886  ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT 945

Query: 1310 ASTASPATTSTA----QSTTRTTM--TLPTPATSGTSPTLPKSTNQELPGTTATQTTGPR 1363
             ST    T + +    ++TT TTM     T +T+G+  T   +   E   TT     G  
Sbjct: 946  VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE---TTTASIEGSE 1002

Query: 1364 PTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVT 1423
             T  S+TG  T         T TETT T T    TT  T        TAGS         
Sbjct: 1003 TTTVSSTGSETTT----VSTTGTETTITSTEGSETTTVT--------TAGS--------- 1041

Query: 1424 ATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGT 1483
                  T  Y T S  ETT  +     +T++ T  + T    T     T+ S   + T  
Sbjct: 1042 ----ETTAVYTTGS--ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGT-- 1093

Query: 1484 IPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTT 1543
                TT    GS  T   IT + + T+    S +T  + TS  + T+ST   E+T   TT
Sbjct: 1094 ----TTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149

Query: 1544 TITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYP 1603
                  T+  T    A T+SA  S      T  S  T +S   S     +T+   TTT  
Sbjct: 1150 --VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTAS 1207

Query: 1604 TPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATG 1663
            T     TT  T     +T+  T S  +  TP+ A   T+ +       TI    +L+ T 
Sbjct: 1208 TAGSETTTASTSGSETNTACTTGSETS--TPSSAGSETNTAFIIGSETTIASTASLEPTA 1265

Query: 1664 STHT---APTMTLTTSGTSQALSSLN------TAKTSTSLHSHTSSTHHAEATSTSTTNI 1714
            ++ T     T+++T SG + A ++++      T  T  S+   T++      T T+ T +
Sbjct: 1266 TSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTP--MSGTRTTGTRL 1323

Query: 1715 TPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT 1774
            T + + T  P M  T S  S          T   +  +TS      + ++STTS     T
Sbjct: 1324 TASSSVTMAPGMDFTASAASH---------TVPGIVLNTSGLGTSTMGASSTTSAHGVRT 1374

Query: 1775 STG-TRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGP 1814
            +TG TR P + T   T    P    T++     TP +   P
Sbjct: 1375 TTGSTREPTSSTFQETG---PVSMGTNTVSMSHTPTNVIKP 1412


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score =  276 bits (707), Expect = 1e-73
 Identities = 340/1237 (27%), Positives = 510/1237 (41%), Gaps = 120/1237 (9%)

Query: 1215 SRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEP-PR 1273
            S  T V P  G++TT    S+TG          S T T L+ A+ T++  TA S    P 
Sbjct: 2    SSETTVAPAAGSNTTTA--STTG----------SETTTILIKASETTTASTAGSETTTPS 49

Query: 1274 PT-----------TAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQ 1322
            PT           + +T  +T+G   T    + +   T + A +  T STA   TT+ + 
Sbjct: 50   PTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI 109

Query: 1323 STTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP-TTPQPGQPT 1381
            + T TTM     +  G+  T   +T+ E   TT T T G   T  ST G  TT      +
Sbjct: 110  TGTETTMV----SAMGSETTTNSTTSSE---TTVTSTAGSETTTVSTVGSETTTAYTADS 162

Query: 1382 RPTATETTQTRTTTEYTTPQ---TPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSH 1438
              TA  TT +  TT +T      TP T  S  T  S   S     +T+   TTT  T +H
Sbjct: 163  ETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST-AH 221

Query: 1439 PETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTI----PPPTTLKATG 1494
             ETT  + +   +T + T  + T ++ T     T+AS   + T T        TT   TG
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVS-TAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 1495 STHTAPPIT---PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551
               TA   T   PT + T  + ++ ++   P +    T+S+    V    + TI  +   
Sbjct: 281  FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 1552 TRTRTPVAHTNSATS------SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTP 1605
            + T T V+ T S T+      S      TT S  T +S   S     +T     TT  T 
Sbjct: 341  SETTT-VSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTT 399

Query: 1606 SHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT--GTIPPPTTLKATG 1663
                TT+       +T+    S  T ++ T  +  T+++  S  T   T    TT   T 
Sbjct: 400  GSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT---TA 456

Query: 1664 STHTAPTMTLTTSG----TSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI-TPNP 1718
            ST  + T T+TT+G    T+    S  T  ++T L + T  T  ++ T+ ST    T   
Sbjct: 457  STEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV 516

Query: 1719 TSTGTPPMTVTTSG----TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT 1774
            ++TG+   TV+T G    T  +  S +T  ++T L + T+ST   E+T+ STT       
Sbjct: 517  SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTD 576

Query: 1775 ST-GTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPH 1833
            ST G+ T  A T  + ++ + T  + ++  T +T  S T   + T  +TTT   T S   
Sbjct: 577  STEGSGTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSE-- 632

Query: 1834 TTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAP 1893
            TT  +   S +T++ T  + T ++ T     T  S     T      TT+ ATGS  T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET------TTVSATGSETTVS 686

Query: 1894 PM---TPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTS------TTNITPKHTS 1944
                 T T S T    +  ST  + T+    T+ST   E+T  S      TT  T    +
Sbjct: 687  TEGSGTTTVSITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSET 742

Query: 1945 TGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ 2002
            T   T  + TTSAS+  S   T  TT S  T +S   S   M +T    TT   T S   
Sbjct: 743  TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802

Query: 2003 TTLPTHVPPFSTSLVTPSTHTVIITTHTQ---MATSASIHSTPTGTVPPPTTLKATGSTH 2059
            TT+ T     + +  T S  T + T  ++    +T+ S  +T T T    TT  +T  + 
Sbjct: 803  TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862

Query: 2060 TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT 2119
            T    T ++  T+ T     T TAS+    +++   + S         TT      S  T
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSE--------TTTASTEGSEIT 914

Query: 2120 PVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGS 2179
             VSTT   +++ S   S  +T      S+  S  T+  + G+ +  VSA    TT    +
Sbjct: 915  TVSTTGSETTTASTEGSETTTA-----STEGSELTTVSTTGSETITVSAEGSETT----T 965

Query: 2180 HSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSS 2239
             +++ +  TTAS + S     S A S T  A++     S  T  +     T TVS T + 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTE 1022

Query: 2240 HLASSTIAFPSTPRTTASTHTAPAF---SSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP 2296
               +ST    +T  TTA + T   +   S  +TTS   S TT V T+G  + T+    + 
Sbjct: 1023 TTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLE 1082

Query: 2297 TSPVTNL---TTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVRE 2353
            T+ V+     TT         TT ++T S T   ST  S   +   T + T+    +  E
Sbjct: 1083 TTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142

Query: 2354 QQEEITFKGCMANVTVTRCEGACISAASFNIITQQVD 2390
                 T       V+    E    SAA     T   +
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179



 Score =  266 bits (681), Expect = 1e-70
 Identities = 329/1195 (27%), Positives = 491/1195 (41%), Gaps = 132/1195 (11%)

Query: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEP 1271
            T GS  T V  +TGT TT  ++S+ G   ++N T              TSS+ T +S   
Sbjct: 99   TAGSETTTV-SITGTETT--MVSAMGSETTTNST--------------TSSETTVTSTAG 141

Query: 1272 PRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMT- 1330
               TT  T  + +    TA   +TA   T ++ TT  TA + +  T STA S T T  T 
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSET-ITPSTAGSETTTVSTA 200

Query: 1331 ---LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG--PTTPQPGQPTRPTA 1385
                 T +T+G+  T   + + E   TTA  T G   T  ST G   T    G  T   +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSE---TTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 1386 TETTQTRTT-TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLP 1444
            TE ++T T  TE +   T  TT    TA S   S  P  A++  + TT  +   PETT  
Sbjct: 258  TEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE-PTMASTMGSETTMASTIGPETTKV 316

Query: 1445 THVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504
            +      T++    + T+           AS   + T      TT+  TGS  T   I  
Sbjct: 317  STASSEVTTVFAAGSETI----------RASTVGSET------TTVSTTGSETTTASIMG 360

Query: 1505 TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTT---TITPNPTSTRTRTPVAHT 1561
            + + T     S +T  +     + T+ST   E T  STT   T T + T + T T     
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 1562 NSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFST 1621
            +  T+       TT    T +S   S   + +TS   TTT  T     TT+ T      T
Sbjct: 421  SEMTAVS-----TTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 1622 SLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQA 1681
            +  T S  T  + T  +  T  +I S         TT    GS  TA + T +   T   
Sbjct: 476  AYTTGSETTTASNTGLETTTVFTIGS-------DTTTASTEGSETTAVSATGSEMTTVST 528

Query: 1682 LSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS-TGTPPMTVTTSGTSQSRSSF 1740
              S NT  ++T   + T ST   E T+TST        S TG    T +T G+  + +S 
Sbjct: 529  EGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588

Query: 1741 STAKTST----SLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSAT-SSRLPT 1795
            + ++T+T       + T+ST   E TS STT    + T+T + T    TT++T  S   T
Sbjct: 589  AGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEGSETTT 645

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTV 1855
              TT S  T  +   S   +T+T    TTT  + +   TT+ T     +T  +T S  T 
Sbjct: 646  VSTTDSETTMVSTTGSERTITSTEGSETTTV-SATGSETTVSTEGSGTTTVSITGSETTK 704

Query: 1856 IIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
            +  T ++  T+++  S         TT   TGS  T      + + T+ +  S +T+ ++
Sbjct: 705  VSTTGSETTTTSTEGS-------EITTASITGSETTTASTEGSETTTASTEGSETTSAST 757

Query: 1916 TSLPYHTSSTHHPEVTPTSTTNITPKHTST-GTRTPVAHTTSASSSRLPTPFTTHSPPTG 1974
            T     T+ST   E T  S         ST G+ T      S +SS++ T FT +S  T 
Sbjct: 758  TGSETTTASTTSSETTMASIMGSETTMASTIGSETT---KVSTASSKMTTVFTENSETTI 814

Query: 1975 SSPFSS-----------TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHT 2023
            +S  +S           T P +    +TTTT  T     TT  T     +T+  T S+ T
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE-TTTASTESSET 873

Query: 2024 VIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSS-----F 2078
               TT     T+AS   + T T     +   T ST  +   TV+T+G+  T +S      
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 2079 STATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAP 2138
            +TA+   S +++ S     + +       TT +  + S TT  ST    +++ S + S  
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 2139 STVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLF 2198
            +T      S   S  T+  S G+ ++ VS     TT++S   S  +T  T  S + +   
Sbjct: 994  TTA-----SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYT 1048

Query: 2199 PSSPAASTTIRATLPHTIS---SPFTLSALLPISTVTVSPTPSSHLASSTIAFPST---- 2251
              S   +T+   +   T+S   S  T ++   + T TVS + S    +ST    +T    
Sbjct: 1049 TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYI 1108

Query: 2252 ---PRTTASTH-----TAPAFSSQSTTSRST-----------SLTTRVPTSGFVSLTSGV 2292
                 TTAST      T    SS++TT+ +T           S TT V T G  + TS  
Sbjct: 1109 TGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSA 1168

Query: 2293 TGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPG 2347
             G   S  T  +T     T + T    T++ +  GS   +A  S   T T  + G
Sbjct: 1169 AG---SEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1220



 Score =  262 bits (670), Expect = 3e-69
 Identities = 327/1195 (27%), Positives = 485/1195 (40%), Gaps = 120/1195 (10%)

Query: 1207 TPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTA 1266
            T  + T GS  T  +     +T     S+TG   ++  T  S T TP    + T++  TA
Sbjct: 144  TTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1267 SSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT--VTQATTRATASTASPATT--STAQ 1322
             S      TT       S      T  ST    T  V+ A +  T STA   TT  ST  
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTED 260

Query: 1323 STTRTTMT----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPG 1378
            S T T  T      T +T+G   T   +T  E    T   T G   T AST GP T +  
Sbjct: 261  SETNTAFTEDSKTTTASTTGFETTAASTTGSE---PTMASTMGSETTMASTIGPETTKVS 317

Query: 1379 QPTRPTAT------ETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432
              +    T      ET +  T    TT  T  TT S  T  S + S     +T+   TTT
Sbjct: 318  TASSEVTTVFAAGSETIRASTVGSETT--TVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTG---TIPPPTT 1489
              T     TT  T     +T   T S  T ++ T ++  T+ +  S  T    T+   TT
Sbjct: 376  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 1490 LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNP 1549
                GS  T    + + + T+    S +T  T     + T+ T   E T  S T +    
Sbjct: 436  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGL--ET 493

Query: 1550 TSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQ 1609
            T+  T      T S   S       T S  T  S   S     +T+   TTT  T     
Sbjct: 494  TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLET 553

Query: 1610 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAP 1669
            TT  T     +T + T    T    T     T+AS     T T+    +   T ST  + 
Sbjct: 554  TTTSTEGSEMTT-VSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 1670 TMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVT 1729
            T + +T+G+        T  ++TS  + T+ST  +E T+ STT+         +    V+
Sbjct: 613  TTSASTTGSE------TTTASTTSSETTTASTEGSETTTVSTTD---------SETTMVS 657

Query: 1730 TSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT----STGTRTPVAH- 1784
            T+G+ ++ +S   ++T+T   + + +T   E + T+T SIT + T    +TG+ T     
Sbjct: 658  TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST 717

Query: 1785 ------TTSATSSRLPTPFTTHSPPT-------GTTPISSTGPVTATSFQTT--TTYPTP 1829
                  T S T S   T  T  S  T        TT  S+TG  T T+  T+  TT  + 
Sbjct: 718  EGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 1830 SHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGST 1889
                TT+ + + S +T + T S+    + T     T AS       T    TT  +T  +
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS-------TTASETTTVSTAGS 830

Query: 1890 HTAPPMT---PTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPT------STTNITP 1940
             T P  T    TT+ TS   S  +TA T  S    T+ST   E T        +TT  T 
Sbjct: 831  ETIPASTAGSETTTTTSTEGSETTTASTEGS-ETTTASTESSETTTATTIGSETTTASTE 889

Query: 1941 KHTSTGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTP 1998
               +T T T  + TT+AS+  S + T  TT S  T +S   S     +T     TT  T 
Sbjct: 890  GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTT 949

Query: 1999 SH---------PQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP 2049
                        +TT  T +   +T+  T  + T  ++T     T+ASI  + T      
Sbjct: 950  GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET------ 1003

Query: 2050 TTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT 2109
            TT+ +TGS  T    TV+T+GT  T     T+T  S   + ++   + ++     S  TT
Sbjct: 1004 TTVSSTGSETT----TVSTTGTETT----ITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055

Query: 2110 QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAP 2169
                  S TT VSTT   +++ S +    +TVS+   S   +   S+    T++ +++  
Sbjct: 1056 TSTE-GSETTTVSTTGSETTTASTADLETTTVST---SGSGTTTASTAGSETTTVYITGS 1111

Query: 2170 VHSTTLSSGSH----SSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSAL 2225
              +T  + GS     S+ S+  TTAS + S +   +   +T    T   TI S  T S+ 
Sbjct: 1112 KTTTASTEGSEATTVSTTSSETTTASTTGSEM---TTVFTTVSETTTVSTIGSEATTSSA 1168

Query: 2226 LPISTVTVSPTPSSHLASSTIAFPSTPRTTA--STHTAPAFSSQSTTSRSTSLTTRVPTS 2283
                  T S   S    +ST    +T  +TA   T TA    S++ T+ +T   T  P+S
Sbjct: 1169 AGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSS 1228

Query: 2284 -GFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSS 2337
             G  + T+ + G  T+ + +  +  P  T    +   T S+TA G+T AS  VSS
Sbjct: 1229 AGSETNTAFIIGSETT-IASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1282



 Score =  249 bits (637), Expect = 2e-65
 Identities = 293/1129 (25%), Positives = 473/1129 (41%), Gaps = 80/1129 (7%)

Query: 1205 PTTPQLPTTGSRPTQVWPM---TGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTS 1261
            P T ++ T  S  T V+     T  ++T+G  ++T  +  S  T AS   +     + T 
Sbjct: 311  PETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTG 370

Query: 1262 SKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTA 1321
            S+ T +S E    TTA    +T G   T T+ +T ++ T    T   T +T +  +  TA
Sbjct: 371  SETTTASTEGSETTTA----STEGSEAT-TVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 1322 QSTTRTTMTLPTPATSGTSPTLPKSTNQELPG-------TTATQTTGPRPTPASTTGPTT 1374
             STT    T  T +T G+  T+  +++ E          TT   T G     A TTG  T
Sbjct: 426  VSTTVFETT--TASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSET 483

Query: 1375 PQPGQPTRPTATETTQTRTTTEYTTPQTPHT----THSPPTAGSPVPSTGPVTATSFHAT 1430
                     T T  T    TT  +T  +  T    T S  T  S   S     +T+   T
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSET 543

Query: 1431 TTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTL 1490
            TT  T     TT  T      T++ T    T    T     T+AS   + T T+    + 
Sbjct: 544  TTVSTTGLETTTTSTEGSEM-TTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSE 602

Query: 1491 KATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST----TTIT 1546
              T ST  +   + +T+G      S +T  + TS  + T+ST   E T  ST    TT+ 
Sbjct: 603  NTTASTADSETTSASTTG------SETTTASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 1547 PNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMT----ATSFKTTTTY 1602
                S RT T    + + T S      T  +  +G++  S TG  T     T  +TTTT 
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT---GTIPPPTTL 1659
               S  + T  +     +T+  T  + T    T     TSAS     T    T    TT+
Sbjct: 717  TEGS--EITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTM 774

Query: 1660 KATGSTHT--APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPN 1717
             +   + T  A T+   T+  S A S + T  T  S  +  +ST  +E T+ ST      
Sbjct: 775  ASIMGSETTMASTIGSETTKVSTASSKMTTVFTENS-ETTIASTTASETTTVSTAGSETI 833

Query: 1718 PTSTGTPPMTVTTS--GTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTS 1775
            P ST     T TTS  G+  + +S   ++T+T+    + +T    + S +TT+ T    +
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSET 893

Query: 1776 TGTRTPVAHTTSATS--SRLPTPFTTHS-PPTGTTPISSTGPVTATSFQTTTTYPTPSH- 1831
            T T T  + TT+A++  S + T  TT S   T +T  S T   +    + TT   T S  
Sbjct: 894  TTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSET 953

Query: 1832 -------PHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIK 1884
                     TT  T + S +T+  T  + T  + T     T+ASI    T      TT+ 
Sbjct: 954  ITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET------TTVS 1007

Query: 1885 ATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTS 1944
            +TGS  T    T +T+GT  + +S   ++T+T     + +T        +TT  T    +
Sbjct: 1008 STGSETT----TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSET 1063

Query: 1945 TGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT---TTTYPTPSHP 2001
            T   T  + TT+AS++ L T  T  +  +G++  S+ G  T T + T   TTT  T    
Sbjct: 1064 TTVSTTGSETTTASTADLETT-TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSE 1122

Query: 2002 QTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHS---TPTGTVPPPTTLKATGST 2058
             TT+ T     +T+  T S  T + TT ++  T ++I S   T +      TT    GS 
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182

Query: 2059 HTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSAT 2118
             T      + + T+ T  S +T  ++S   ++++    + +S P S+   T    +  + 
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSE 1242

Query: 2119 TPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSG 2178
            T +++T    +S  P+ ++ +   +   S  +S  T++ +  +S++FV       ++   
Sbjct: 1243 TTIAST----ASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPI 1298

Query: 2179 SHSSLS-THPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTP 2237
            +++ +S T  T   ++AS     +P    T  A   HT+      ++ L  ST+  S T 
Sbjct: 1299 TNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAA-SHTVPGIVLNTSGLGTSTMGASSTT 1357

Query: 2238 SSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFV 2286
            S+H   +T      P ++    T P     +T S S + T  +  SG++
Sbjct: 1358 SAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSGYL 1406



 Score =  229 bits (585), Expect = 2e-59
 Identities = 296/1102 (26%), Positives = 452/1102 (41%), Gaps = 158/1102 (14%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTI---GLLSSTGPSPSSNHTPASPTQTPLLP 1256
            TT    T  +  TT +  ++   MT  STT+      S+ G   +   T  S T T    
Sbjct: 403  TTTVSITDSETTTTCTEGSE---MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTE 459

Query: 1257 ATLTSSKPTASSGEPPRPTTA--VTPQATSGLPPTA--TLRSTATKPTVTQATTRATAST 1312
             + T++  TA S      TT    T  + +GL  T   T+ S  T  +   + T A ++T
Sbjct: 460  GSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519

Query: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372
             S  TT + + +  TT++     T+G+  T   +T  E   TT T T G   T  STTG 
Sbjct: 520  GSEMTTVSTEGSENTTVS-----TTGSETTTVSTTGLE---TTTTSTEGSEMTTVSTTGA 571

Query: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432
             T         T   +T    TT  +T  + +TT S  TA S   S     +T+   TTT
Sbjct: 572  ETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS--TADSETTSA----STTGSETTT 625

Query: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKA 1492
              T S   TT  T     +T   T S  T+++ T ++   +++  S  T       T+ A
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT-------TVSA 678

Query: 1493 TGSTHTAPPITPTTSGTSQAH--SSFSTNKTPTSLHSHTSSTHHPEVTPTS------TTT 1544
            TGS  T   ++   SGT+      S +T  + T   + T+ST   E+T  S      TT 
Sbjct: 679  TGSETT---VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 1545 ITPNPTSTRTRTPVAHTNSA--TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTY 1602
             T    +T   T  + T SA  T S      TT S  T +S   S   M +T    TT  
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKAT 1662
             T S   TT+ T     + +  T S  T ++        +A   ++P  T    TT   T
Sbjct: 796  STASSKMTTVFTENSETTIASTTASETTTVS--------TAGSETIPASTAGSETT--TT 845

Query: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSL----HSHTSSTHHAEATSTSTTNITPNP 1718
             ST  + T T +T G+    +S  +++T+T+      + T+ST  +E T+TST       
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 1719 TST-GTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTT---------- 1767
             ST G+   TV+T+G+  + +S   ++T+T+      ST   E+T+ STT          
Sbjct: 906  ASTEGSEITTVSTTGSETTTASTEGSETTTA------STEGSELTTVSTTGSETITVSAE 959

Query: 1768 -SITPNHTSTGTRTPVAHTTSATSSRLPTPF--TTHSPPTG--TTPISSTGPVTAT--SF 1820
             S T   T+ G+ T  A T  + ++ + T    TT +   G  TT +SSTG  T T  + 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1821 QTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPP 1880
             T TT  +     TT  T   S +T++ T  + T    T     T+ S     T T    
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079

Query: 1881 ----TTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTT 1936
                TT+  +GS  T    T +T+G+  +    + +KT+      T+ST   E T  STT
Sbjct: 1080 DLETTTVSTSGSGTT----TASTAGSETTTVYITGSKTT------TASTEGSEATTVSTT 1129

Query: 1937 NITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYP 1996
            +         + T  A TT    S + T FTT S  T  S   S    ++ +    TT  
Sbjct: 1130 S---------SETTTASTT---GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTS 1177

Query: 1997 TPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056
            T     TT                            A++A   +T   T    TT  +T 
Sbjct: 1178 TEGSETTT----------------------------ASTAGSETTTASTAGSETTTASTS 1209

Query: 2057 STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS 2116
             + T      TT   + T SS  + T ++  I S + +   +S  P ++ +T       S
Sbjct: 1210 GSET--NTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLT------GS 1261

Query: 2117 ATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT---------SSSFVS 2167
             TT VS T   +++ S + S+ + V +        P T++P  GT         SSS   
Sbjct: 1262 ETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTM 1321

Query: 2168 APVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHT---ISSPF--TL 2222
            AP    T S+ SH+       T+ +  S +  SS  ++  +R T   T    SS F  T 
Sbjct: 1322 APGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETG 1381

Query: 2223 SALLPISTVTVSPTPSSHLASS 2244
               +  +TV++S TP++ +  S
Sbjct: 1382 PVSMGTNTVSMSHTPTNVIKPS 1403



 Score =  130 bits (326), Expect = 2e-29
 Identities = 165/597 (27%), Positives = 231/597 (38%), Gaps = 73/597 (12%)

Query: 1197 MPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256
            +P +T    TT    T GS  T       T++T G  ++T  + SS  T A+   +    
Sbjct: 833  IPASTAGSETTTTTSTEGSETT-------TASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 1257 ATLTSSKPTASSGEPPRPTTA-------VTPQATSGLPPTATLRSTATKPTVTQATTRAT 1309
            A+   S+ T +S E    TTA        T   T     TA+   + T    T+ +   T
Sbjct: 886  ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT 945

Query: 1310 ASTASPATTSTA----QSTTRTTM--TLPTPATSGTSPTLPKSTNQELPGTTATQTTGPR 1363
             ST    T + +    ++TT TTM     T +T+G+  T   +   E   TT     G  
Sbjct: 946  VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE---TTTASIEGSE 1002

Query: 1364 PTPASTTGPTTPQPGQPTRPTATETTQT---------------RTTTEYTTPQTPHTTHS 1408
             T  S+TG  T         T TETT T                TT  YTT     TT +
Sbjct: 1003 TTTVSSTGSETTT----VSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1058

Query: 1409 PPTAGSPVPSTGPVTATSFHA---TTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITP 1465
              +  + V +TG  T T+  A   TTT  T     TT  T     +T  +T S  T    
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS-KTTTAS 1117

Query: 1466 THAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSL 1525
            T    AT+ S  S+ T      TT   TGS  T    T + + T     S +T  +    
Sbjct: 1118 TEGSEATTVSTTSSET------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGS 1171

Query: 1526 HSHTSSTHHPEVTPTS------TTTITPNPTSTRTRTPVAHTNSA--TSSRPPPPFTTHS 1577
             + T+ST   E T  S      TT  T    +T   T  + TN+A  T S    P +  S
Sbjct: 1172 EATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGS 1231

Query: 1578 PPTGSSPFSSTGPMTAT-SFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTH 1636
                +    S   + +T S + T T  T S   T   T     + S    ST  V+T   
Sbjct: 1232 ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLT--- 1288

Query: 1637 AQMATSASIHSMP----TGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSS--LNTAKT 1690
               AT  SI  +     +GT    T L A+ S   AP M  T S  S  +    LNT+  
Sbjct: 1289 --KATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGL 1346

Query: 1691 STSLHSHTSSTH-HAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS 1746
             TS    +S+T  H   T+T +T    + T   T P+++ T+  S S +  +  K S
Sbjct: 1347 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPS 1403


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score =  276 bits (707), Expect = 1e-73
 Identities = 340/1237 (27%), Positives = 510/1237 (41%), Gaps = 120/1237 (9%)

Query: 1215 SRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEP-PR 1273
            S  T V P  G++TT    S+TG          S T T L+ A+ T++  TA S    P 
Sbjct: 2    SSETTVAPAAGSNTTTA--STTG----------SETTTILIKASETTTASTAGSETTTPS 49

Query: 1274 PT-----------TAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQ 1322
            PT           + +T  +T+G   T    + +   T + A +  T STA   TT+ + 
Sbjct: 50   PTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSI 109

Query: 1323 STTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP-TTPQPGQPT 1381
            + T TTM     +  G+  T   +T+ E   TT T T G   T  ST G  TT      +
Sbjct: 110  TGTETTMV----SAMGSETTTNSTTSSE---TTVTSTAGSETTTVSTVGSETTTAYTADS 162

Query: 1382 RPTATETTQTRTTTEYTTPQ---TPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSH 1438
              TA  TT +  TT +T      TP T  S  T  S   S     +T+   TTT  T +H
Sbjct: 163  ETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTAST-AH 221

Query: 1439 PETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTI----PPPTTLKATG 1494
             ETT  + +   +T + T  + T ++ T     T+AS   + T T        TT   TG
Sbjct: 222  SETTAASTMGSETTKVSTAGSETTVS-TAGSETTAASTEDSETNTAFTEDSKTTTASTTG 280

Query: 1495 STHTAPPIT---PTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551
               TA   T   PT + T  + ++ ++   P +    T+S+    V    + TI  +   
Sbjct: 281  FETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVG 340

Query: 1552 TRTRTPVAHTNSATS------SRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTP 1605
            + T T V+ T S T+      S      TT S  T +S   S     +T     TT  T 
Sbjct: 341  SETTT-VSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTT 399

Query: 1606 SHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT--GTIPPPTTLKATG 1663
                TT+       +T+    S  T ++ T  +  T+++  S  T   T    TT   T 
Sbjct: 400  GSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETT---TA 456

Query: 1664 STHTAPTMTLTTSG----TSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNI-TPNP 1718
            ST  + T T+TT+G    T+    S  T  ++T L + T  T  ++ T+ ST    T   
Sbjct: 457  STEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAV 516

Query: 1719 TSTGTPPMTVTTSG----TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT 1774
            ++TG+   TV+T G    T  +  S +T  ++T L + T+ST   E+T+ STT       
Sbjct: 517  SATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTD 576

Query: 1775 ST-GTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPH 1833
            ST G+ T  A T  + ++ + T  + ++  T +T  S T   + T  +TTT   T S   
Sbjct: 577  STEGSGTTAASTAGSETTTVSTADSENT--TASTADSETTSASTTGSETTTASTTSSE-- 632

Query: 1834 TTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAP 1893
            TT  +   S +T++ T  + T ++ T     T  S     T      TT+ ATGS  T  
Sbjct: 633  TTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET------TTVSATGSETTVS 686

Query: 1894 PM---TPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTS------TTNITPKHTS 1944
                 T T S T    +  ST  + T+    T+ST   E+T  S      TT  T    +
Sbjct: 687  TEGSGTTTVSITGSETTKVSTTGSETT----TTSTEGSEITTASITGSETTTASTEGSET 742

Query: 1945 TGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQ 2002
            T   T  + TTSAS+  S   T  TT S  T +S   S   M +T    TT   T S   
Sbjct: 743  TTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 802

Query: 2003 TTLPTHVPPFSTSLVTPSTHTVIITTHTQ---MATSASIHSTPTGTVPPPTTLKATGSTH 2059
            TT+ T     + +  T S  T + T  ++    +T+ S  +T T T    TT  +T  + 
Sbjct: 803  TTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE 862

Query: 2060 TAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT 2119
            T    T ++  T+ T     T TAS+    +++   + S         TT      S  T
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSE--------TTTASTEGSEIT 914

Query: 2120 PVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGS 2179
             VSTT   +++ S   S  +T      S+  S  T+  + G+ +  VSA    TT    +
Sbjct: 915  TVSTTGSETTTASTEGSETTTA-----STEGSELTTVSTTGSETITVSAEGSETT----T 965

Query: 2180 HSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSS 2239
             +++ +  TTAS + S     S A S T  A++     S  T  +     T TVS T + 
Sbjct: 966  VTTMGSETTTASTAGSETTTVSTAGSETTTASIE---GSETTTVSSTGSETTTVSTTGTE 1022

Query: 2240 HLASSTIAFPSTPRTTASTHTAPAF---SSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIP 2296
               +ST    +T  TTA + T   +   S  +TTS   S TT V T+G  + T+    + 
Sbjct: 1023 TTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLE 1082

Query: 2297 TSPVTNL---TTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPGVCSVRE 2353
            T+ V+     TT         TT ++T S T   ST  S   +   T + T+    +  E
Sbjct: 1083 TTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSE 1142

Query: 2354 QQEEITFKGCMANVTVTRCEGACISAASFNIITQQVD 2390
                 T       V+    E    SAA     T   +
Sbjct: 1143 MTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179



 Score =  266 bits (681), Expect = 1e-70
 Identities = 329/1195 (27%), Positives = 491/1195 (41%), Gaps = 132/1195 (11%)

Query: 1212 TTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEP 1271
            T GS  T V  +TGT TT  ++S+ G   ++N T              TSS+ T +S   
Sbjct: 99   TAGSETTTV-SITGTETT--MVSAMGSETTTNST--------------TSSETTVTSTAG 141

Query: 1272 PRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMT- 1330
               TT  T  + +    TA   +TA   T ++ TT  TA + +  T STA S T T  T 
Sbjct: 142  SETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSET-ITPSTAGSETTTVSTA 200

Query: 1331 ---LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTG--PTTPQPGQPTRPTA 1385
                 T +T+G+  T   + + E   TTA  T G   T  ST G   T    G  T   +
Sbjct: 201  GSETTTVSTTGSETTTASTAHSE---TTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 1386 TETTQTRTT-TEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLP 1444
            TE ++T T  TE +   T  TT    TA S   S  P  A++  + TT  +   PETT  
Sbjct: 258  TEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE-PTMASTMGSETTMASTIGPETTKV 316

Query: 1445 THVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITP 1504
            +      T++    + T+           AS   + T      TT+  TGS  T   I  
Sbjct: 317  STASSEVTTVFAAGSETI----------RASTVGSET------TTVSTTGSETTTASIMG 360

Query: 1505 TTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTT---TITPNPTSTRTRTPVAHT 1561
            + + T     S +T  +     + T+ST   E T  STT   T T + T + T T     
Sbjct: 361  SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEG 420

Query: 1562 NSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFST 1621
            +  T+       TT    T +S   S   + +TS   TTT  T     TT+ T      T
Sbjct: 421  SEMTAVS-----TTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKT 475

Query: 1622 SLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQA 1681
            +  T S  T  + T  +  T  +I S         TT    GS  TA + T +   T   
Sbjct: 476  AYTTGSETTTASNTGLETTTVFTIGS-------DTTTASTEGSETTAVSATGSEMTTVST 528

Query: 1682 LSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTS-TGTPPMTVTTSGTSQSRSSF 1740
              S NT  ++T   + T ST   E T+TST        S TG    T +T G+  + +S 
Sbjct: 529  EGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAAST 588

Query: 1741 STAKTST----SLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSAT-SSRLPT 1795
            + ++T+T       + T+ST   E TS STT    + T+T + T    TT++T  S   T
Sbjct: 589  AGSETTTVSTADSENTTASTADSETTSASTTG---SETTTASTTSSETTTASTEGSETTT 645

Query: 1796 PFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTV 1855
              TT S  T  +   S   +T+T    TTT  + +   TT+ T     +T  +T S  T 
Sbjct: 646  VSTTDSETTMVSTTGSERTITSTEGSETTTV-SATGSETTVSTEGSGTTTVSITGSETTK 704

Query: 1856 IIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTS 1915
            +  T ++  T+++  S         TT   TGS  T      + + T+ +  S +T+ ++
Sbjct: 705  VSTTGSETTTTSTEGS-------EITTASITGSETTTASTEGSETTTASTEGSETTSAST 757

Query: 1916 TSLPYHTSSTHHPEVTPTSTTNITPKHTST-GTRTPVAHTTSASSSRLPTPFTTHSPPTG 1974
            T     T+ST   E T  S         ST G+ T      S +SS++ T FT +S  T 
Sbjct: 758  TGSETTTASTTSSETTMASIMGSETTMASTIGSETT---KVSTASSKMTTVFTENSETTI 814

Query: 1975 SSPFSS-----------TGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHT 2023
            +S  +S           T P +    +TTTT  T     TT  T     +T+  T S+ T
Sbjct: 815  ASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSE-TTTASTESSET 873

Query: 2024 VIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSS-----F 2078
               TT     T+AS   + T T     +   T ST  +   TV+T+G+  T +S      
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 2079 STATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAP 2138
            +TA+   S +++ S     + +       TT +  + S TT  ST    +++ S + S  
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSET 993

Query: 2139 STVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLF 2198
            +T      S   S  T+  S G+ ++ VS     TT++S   S  +T  T  S + +   
Sbjct: 994  TTA-----SIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYT 1048

Query: 2199 PSSPAASTTIRATLPHTIS---SPFTLSALLPISTVTVSPTPSSHLASSTIAFPST---- 2251
              S   +T+   +   T+S   S  T ++   + T TVS + S    +ST    +T    
Sbjct: 1049 TGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYI 1108

Query: 2252 ---PRTTASTH-----TAPAFSSQSTTSRST-----------SLTTRVPTSGFVSLTSGV 2292
                 TTAST      T    SS++TT+ +T           S TT V T G  + TS  
Sbjct: 1109 TGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSA 1168

Query: 2293 TGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTSPG 2347
             G   S  T  +T     T + T    T++ +  GS   +A  S   T T  + G
Sbjct: 1169 AG---SEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTG 1220



 Score =  261 bits (668), Expect = 5e-69
 Identities = 327/1195 (27%), Positives = 484/1195 (40%), Gaps = 120/1195 (10%)

Query: 1207 TPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTA 1266
            T  + T GS  T  +     +T     S+TG   ++  T  S T TP    + T++  TA
Sbjct: 144  TTTVSTVGSETTTAYTADSETTAA---STTGSEMTTVFTAGSETITPSTAGSETTTVSTA 200

Query: 1267 SSGEPPRPTTAVTPQATSGLPPTATLRSTATKPT--VTQATTRATASTASPATT--STAQ 1322
             S      TT       S      T  ST    T  V+ A +  T STA   TT  ST  
Sbjct: 201  GSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTED 260

Query: 1323 STTRTTMT----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPG 1378
            S T T  T      T +T+G   T   +T  E    T   T G   T AST GP T +  
Sbjct: 261  SETNTAFTEDSKTTTASTTGFETTAASTTGSE---PTMASTMGSETTMASTIGPETTKVS 317

Query: 1379 QPTRPTAT------ETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432
              +    T      ET +  T    TT  T  TT S  T  S + S     +T+   TTT
Sbjct: 318  TASSEVTTVFAAGSETIRASTVGSETT--TVSTTGSETTTASIMGSETSTDSTTGSETTT 375

Query: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTG---TIPPPTT 1489
              T     TT  T     +T   T S  T ++ T ++  T+ +  S  T    T+   TT
Sbjct: 376  ASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTT 435

Query: 1490 LKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNP 1549
                GS  T    + + + T+    S +T  T     + T+ T   E T  S T +    
Sbjct: 436  ASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGL--ET 493

Query: 1550 TSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQ 1609
            T+  T      T S   S       T S  T  S   S     +T+   TTT  T     
Sbjct: 494  TTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLET 553

Query: 1610 TTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAP 1669
            TT  T     +T + T    T    T     T+AS     T T+    +   T ST  + 
Sbjct: 554  TTTSTEGSEMTT-VSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSE 612

Query: 1670 TMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVT 1729
            T + +T+G+        T  ++TS  + T+ST  +E T+ STT+         +    V+
Sbjct: 613  TTSASTTGSE------TTTASTTSSETTTASTEGSETTTVSTTD---------SETTMVS 657

Query: 1730 TSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHT----STGTRTPVAH- 1784
            T+G+ ++ +S   ++T+T   + + +T   E + T+T SIT + T    +TG+ T     
Sbjct: 658  TTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST 717

Query: 1785 ------TTSATSSRLPTPFTTHSPPT-------GTTPISSTGPVTATSFQTT--TTYPTP 1829
                  T S T S   T  T  S  T        TT  S+TG  T T+  T+  TT  + 
Sbjct: 718  EGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASI 777

Query: 1830 SHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGST 1889
                TT+ + + S +T + T S+    + T     T AS       T    TT  +T  +
Sbjct: 778  MGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS-------TTASETTTVSTAGS 830

Query: 1890 HTAPPMT---PTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPT------STTNITP 1940
             T P  T    TT+ TS   S  +TA T  S    T+ST   E T        +TT  T 
Sbjct: 831  ETIPASTAGSETTTTTSTEGSETTTASTEGS-ETTTASTESSETTTATTIGSETTTASTE 889

Query: 1941 KHTSTGTRTPVAHTTSASS--SRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTP 1998
               +T T T  + TT+AS+  S + T  TT S  T +S   S     +T     TT  T 
Sbjct: 890  GSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTT 949

Query: 1999 SH---------PQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP 2049
                        +TT  T +   +T+  T  + T  ++T     T+ASI  + T      
Sbjct: 950  GSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET------ 1003

Query: 2050 TTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITT 2109
            TT+ +TGS  T    TV+T+GT  T     T+T  S   + ++   + ++     S  TT
Sbjct: 1004 TTVSSTGSETT----TVSTTGTETT----ITSTEGSETTTVTTAGSETTAVYTTGSETTT 1055

Query: 2110 QLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAP 2169
                  S TT VSTT   +++ S +    +TVS+   S   +   S+    T++ +++  
Sbjct: 1056 TSTE-GSETTTVSTTGSETTTASTADLETTTVST---SGSGTTTASTAGSETTTVYITGS 1111

Query: 2170 VHSTTLSSGSH----SSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSAL 2225
              +T  + GS     S+ S+  TTAS + S +   +   +T    T   TI S  T S+ 
Sbjct: 1112 KTTTASTEGSEATTVSTTSSETTTASTTGSEM---TTVFTTVSETTTVSTIGSEATTSSA 1168

Query: 2226 LPISTVTVSPTPSSHLASSTIAFPSTPRTTA--STHTAPAFSSQSTTSRSTSLTTRVPTS 2283
                  T S   S    +ST    +T  +TA   T TA    S++ T+ +T   T  P+S
Sbjct: 1169 AGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSS 1228

Query: 2284 -GFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSS 2337
             G  + T+ + G   S + +  +  P  T    +   T S+TA G+T AS  VSS
Sbjct: 1229 AGSETNTAFIIG-SESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1282



 Score =  251 bits (642), Expect = 5e-66
 Identities = 298/1127 (26%), Positives = 477/1127 (42%), Gaps = 76/1127 (6%)

Query: 1205 PTTPQLPTTGSRPTQVWPM---TGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTS 1261
            P T ++ T  S  T V+     T  ++T+G  ++T  +  S  T AS   +     + T 
Sbjct: 311  PETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTG 370

Query: 1262 SKPTASSGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTA 1321
            S+ T +S E    TTA    +T G   T T+ +T ++ T    T   T +T +  +  TA
Sbjct: 371  SETTTASTEGSETTTA----STEGSEAT-TVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 1322 QSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPT 1381
             STT    T  T +T G+  T+  +++ E   TT   T G   T  +T G  T       
Sbjct: 426  VSTTVFETT--TASTEGSEITIASTSDSE---TTTASTEGSETTTVTTAGSETKTAYTTG 480

Query: 1382 RPTATET-TQTRTTTEYTTPQ---TPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPS 1437
              T T + T   TTT +T      T  T  S  TA S   S     +T     TT  T  
Sbjct: 481  SETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTG 540

Query: 1438 HPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPP---PTTLKATG 1494
               TT+ T     +T+    S  T ++ T A+  T ++  S  T         TT+    
Sbjct: 541  SETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTAD 600

Query: 1495 STHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTT----TITPNPT 1550
            S +T      + + ++    S +T  + TS  + T+ST   E T  STT    T+     
Sbjct: 601  SENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTG 660

Query: 1551 STRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTA----TSFKTTTTYPTPS 1606
            S RT T    + + T S      T  +  +G++  S TG  T     T  +TTTT    S
Sbjct: 661  SERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGS 720

Query: 1607 HPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT---GTIPPPTTLKATG 1663
               T   T     +T+  T  + T    T     TSAS     T    T    TT+ +  
Sbjct: 721  EITTASITGSE--TTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIM 778

Query: 1664 STHT--APTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTST 1721
             + T  A T+   T+  S A S + T  T  S  +  +ST  +E T+ ST      P ST
Sbjct: 779  GSETTMASTIGSETTKVSTASSKMTTVFTENS-ETTIASTTASETTTVSTAGSETIPAST 837

Query: 1722 GTPPMTVTTS--GTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTR 1779
                 T TTS  G+  + +S   ++T+T+    + +T    + S +TT+ T    +T T 
Sbjct: 838  AGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTS 897

Query: 1780 TPVAHTTSATS--SRLPTPFTTHSPPT-GTTPISSTGPVTATSFQTTTTYPTPSHP---- 1832
            T  + TT+A++  S + T  TT S  T  +T  S T   +    + TT   T S      
Sbjct: 898  TEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVS 957

Query: 1833 ----HTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGS 1888
                 TT  T + S +T+  T  + T  + T     T+ASI    T      TT+ +TGS
Sbjct: 958  AEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSET------TTVSSTGS 1011

Query: 1889 THTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTSTGTR 1948
              T    T +T+GT  + +S   ++T+T     + +T        +TT  T    +T   
Sbjct: 1012 ETT----TVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVS 1067

Query: 1949 TPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT---TTTYPTPSHPQTTL 2005
            T  + TT+AS++ L T  T  +  +G++  S+ G  T T + T   TTT  T     TT+
Sbjct: 1068 TTGSETTTASTADLETT-TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTV 1126

Query: 2006 PTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHTAPPMT 2065
             T     +T+  T S  T + TT ++  T ++I S  T T     +   T ST  +   T
Sbjct: 1127 STTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEAT-TSSAAGSEATTTSTEGSETTT 1185

Query: 2066 VTTSGTSQTHSSFS---TATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTPVS 2122
             +T+G+  T +S +   T TAS+S   +++     S +  PSS  +      ++    + 
Sbjct: 1186 ASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSE-----TNTAFIIG 1240

Query: 2123 TTNQLSSSFSPSPSAPSTVSSYVP--SSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSH 2180
            + + ++S+ S  P+A S   S     S  +S  T++ +  +S++FV       ++   ++
Sbjct: 1241 SESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITN 1300

Query: 2181 SSLS-THPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTPSS 2239
            + +S T  T   ++AS     +P    T  A   HT+      ++ L  ST+  S T S+
Sbjct: 1301 TPMSGTRTTGTRLTASSSVTMAPGMDFTASAA-SHTVPGIVLNTSGLGTSTMGASSTTSA 1359

Query: 2240 HLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFV 2286
            H   +T      P ++    T P     +T S S + T  +  SG++
Sbjct: 1360 HGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPSGYL 1406



 Score =  231 bits (588), Expect = 9e-60
 Identities = 297/1102 (26%), Positives = 452/1102 (41%), Gaps = 158/1102 (14%)

Query: 1200 TTPQPPTTPQLPTTGSRPTQVWPMTGTSTTI---GLLSSTGPSPSSNHTPASPTQTPLLP 1256
            TT    T  +  TT +  ++   MT  STT+      S+ G   +   T  S T T    
Sbjct: 403  TTTVSITDSETTTTCTEGSE---MTAVSTTVFETTTASTEGSEITIASTSDSETTTASTE 459

Query: 1257 ATLTSSKPTASSGEPPRPTTA--VTPQATSGLPPTA--TLRSTATKPTVTQATTRATAST 1312
             + T++  TA S      TT    T  + +GL  T   T+ S  T  +   + T A ++T
Sbjct: 460  GSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSAT 519

Query: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372
             S  TT + + +  TT++     T+G+  T   +T  E   TT T T G   T  STTG 
Sbjct: 520  GSEMTTVSTEGSENTTVS-----TTGSETTTVSTTGLE---TTTTSTEGSEMTTVSTTGA 571

Query: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432
             T         T   +T    TT  +T  + +TT S  TA S   S     +T+   TTT
Sbjct: 572  ETTTDSTEGSGTTAASTAGSETTTVSTADSENTTAS--TADSETTSA----STTGSETTT 625

Query: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKA 1492
              T S   TT  T     +T   T S  T+++ T ++   +++  S  T       T+ A
Sbjct: 626  ASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT-------TVSA 678

Query: 1493 TGSTHTAPPITPTTSGTSQAH--SSFSTNKTPTSLHSHTSSTHHPEVTPTS------TTT 1544
            TGS  T   ++   SGT+      S +T  + T   + T+ST   E+T  S      TT 
Sbjct: 679  TGSETT---VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTA 735

Query: 1545 ITPNPTSTRTRTPVAHTNSA--TSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTY 1602
             T    +T   T  + T SA  T S      TT S  T +S   S   M +T    TT  
Sbjct: 736  STEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKV 795

Query: 1603 PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKAT 1662
             T S   TT+ T     + +  T S  T ++        +A   ++P  T    TT   T
Sbjct: 796  STASSKMTTVFTENSETTIASTTASETTTVS--------TAGSETIPASTAGSETT--TT 845

Query: 1663 GSTHTAPTMTLTTSGTSQALSSLNTAKTSTSL----HSHTSSTHHAEATSTSTTNITPNP 1718
             ST  + T T +T G+    +S  +++T+T+      + T+ST  +E T+TST       
Sbjct: 846  TSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTT 905

Query: 1719 TST-GTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTT---------- 1767
             ST G+   TV+T+G+  + +S   ++T+T+      ST   E+T+ STT          
Sbjct: 906  ASTEGSEITTVSTTGSETTTASTEGSETTTA------STEGSELTTVSTTGSETITVSAE 959

Query: 1768 -SITPNHTSTGTRTPVAHTTSATSSRLPTPF--TTHSPPTG--TTPISSTGPVTAT--SF 1820
             S T   T+ G+ T  A T  + ++ + T    TT +   G  TT +SSTG  T T  + 
Sbjct: 960  GSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTT 1019

Query: 1821 QTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPP 1880
             T TT  +     TT  T   S +T++ T  + T    T     T+ S     T T    
Sbjct: 1020 GTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA 1079

Query: 1881 ----TTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTT 1936
                TT+  +GS  T    T +T+G+  +    + +KT+      T+ST   E T  STT
Sbjct: 1080 DLETTTVSTSGSGTT----TASTAGSETTTVYITGSKTT------TASTEGSEATTVSTT 1129

Query: 1937 NITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYP 1996
            +         + T  A TT    S + T FTT S  T  S   S    ++ +    TT  
Sbjct: 1130 S---------SETTTASTT---GSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTS 1177

Query: 1997 TPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056
            T     TT                            A++A   +T   T    TT  +T 
Sbjct: 1178 TEGSETTT----------------------------ASTAGSETTTASTAGSETTTASTS 1209

Query: 2057 STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS 2116
             + T      TT   + T SS  + T ++  I S S +   +S  P ++ +T       S
Sbjct: 1210 GSET--NTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLT------GS 1261

Query: 2117 ATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGT---------SSSFVS 2167
             TT VS T   +++ S + S+ + V +        P T++P  GT         SSS   
Sbjct: 1262 ETTTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTM 1321

Query: 2168 APVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHT---ISSPF--TL 2222
            AP    T S+ SH+       T+ +  S +  SS  ++  +R T   T    SS F  T 
Sbjct: 1322 APGMDFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETG 1381

Query: 2223 SALLPISTVTVSPTPSSHLASS 2244
               +  +TV++S TP++ +  S
Sbjct: 1382 PVSMGTNTVSMSHTPTNVIKPS 1403



 Score =  130 bits (328), Expect = 1e-29
 Identities = 165/597 (27%), Positives = 231/597 (38%), Gaps = 73/597 (12%)

Query: 1197 MPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLP 1256
            +P +T    TT    T GS  T       T++T G  ++T  + SS  T A+   +    
Sbjct: 833  IPASTAGSETTTTTSTEGSETT-------TASTEGSETTTASTESSETTTATTIGSETTT 885

Query: 1257 ATLTSSKPTASSGEPPRPTTA-------VTPQATSGLPPTATLRSTATKPTVTQATTRAT 1309
            A+   S+ T +S E    TTA        T   T     TA+   + T    T+ +   T
Sbjct: 886  ASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTT 945

Query: 1310 ASTASPATTSTA----QSTTRTTM--TLPTPATSGTSPTLPKSTNQELPGTTATQTTGPR 1363
             ST    T + +    ++TT TTM     T +T+G+  T   +   E   TT     G  
Sbjct: 946  VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE---TTTASIEGSE 1002

Query: 1364 PTPASTTGPTTPQPGQPTRPTATETTQT---------------RTTTEYTTPQTPHTTHS 1408
             T  S+TG  T         T TETT T                TT  YTT     TT +
Sbjct: 1003 TTTVSSTGSETTT----VSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTST 1058

Query: 1409 PPTAGSPVPSTGPVTATSFHA---TTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITP 1465
              +  + V +TG  T T+  A   TTT  T     TT  T     +T  +T S  T    
Sbjct: 1059 EGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS-KTTTAS 1117

Query: 1466 THAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSL 1525
            T    AT+ S  S+ T      TT   TGS  T    T + + T     S +T  +    
Sbjct: 1118 TEGSEATTVSTTSSET------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGS 1171

Query: 1526 HSHTSSTHHPEVTPTS------TTTITPNPTSTRTRTPVAHTNSA--TSSRPPPPFTTHS 1577
             + T+ST   E T  S      TT  T    +T   T  + TN+A  T S    P +  S
Sbjct: 1172 EATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGS 1231

Query: 1578 PPTGSSPFSSTGPMTAT-SFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTH 1636
                +    S   + +T S + T T  T S   T   T     + S    ST  V+T   
Sbjct: 1232 ETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSSTTFVLT--- 1288

Query: 1637 AQMATSASIHSMP----TGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSS--LNTAKT 1690
               AT  SI  +     +GT    T L A+ S   AP M  T S  S  +    LNT+  
Sbjct: 1289 --KATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGL 1346

Query: 1691 STSLHSHTSSTH-HAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTS 1746
             TS    +S+T  H   T+T +T    + T   T P+++ T+  S S +  +  K S
Sbjct: 1347 GTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGTNTVSMSHTPTNVIKPS 1403


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.125    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 115,446,445
Number of Sequences: 37866
Number of extensions: 6628940
Number of successful extensions: 135969
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 481
Number of HSP's successfully gapped in prelim test: 2049
Number of HSP's that attempted gapping in prelim test: 26829
Number of HSP's gapped (non-prelim): 26038
length of query: 2439
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2320
effective length of database: 13,741,464
effective search space: 31880196480
effective search space used: 31880196480
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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