Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 151101449
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|151101449 solute carrier family 4, sodium bicarbonate
cotransporter, member 9 [Homo sapiens]
(959 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans... 1937 0.0
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo... 942 0.0
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans... 942 0.0
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans... 932 0.0
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap... 852 0.0
gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa... 842 0.0
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp... 808 0.0
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp... 808 0.0
gi|155722998 solute carrier family 4, sodium bicarbonate transpo... 803 0.0
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans... 745 0.0
gi|156071474 solute carrier family 4, anion exchanger, member 2 ... 577 e-164
gi|157671951 solute carrier family 4, anion exchanger, member 3 ... 557 e-158
gi|157671953 solute carrier family 4, anion exchanger, member 3 ... 557 e-158
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H... 496 e-140
gi|14042960 solute carrier family 4 member 11 [Homo sapiens] 209 1e-53
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 33 0.98
gi|47078278 choline kinase alpha isoform b [Homo sapiens] 33 1.3
gi|47078276 choline kinase alpha isoform a [Homo sapiens] 33 1.3
gi|30039700 monoacylglycerol O-acyltransferase 3 [Homo sapiens] 33 1.7
gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo... 32 2.2
gi|20373171 vang-like 1 [Homo sapiens] 32 2.8
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 32 2.8
gi|221139764 PHD and ring finger domains 1 [Homo sapiens] 32 3.7
gi|74271903 chondroitin sulfate synthase 3 [Homo sapiens] 32 3.7
gi|21687212 UV radiation resistance associated [Homo sapiens] 31 4.9
gi|210032580 SET domain containing 1B [Homo sapiens] 31 4.9
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 31 4.9
gi|4885455 SH2B adaptor protein 3 [Homo sapiens] 31 6.3
gi|239747093 PREDICTED: hypothetical protein XP_002344492 [Homo ... 31 6.3
gi|88853066 sperm associated antigen 8 isoform 1 [Homo sapiens] 31 6.3
>gi|151101449 solute carrier family 4, sodium bicarbonate
cotransporter, member 9 [Homo sapiens]
Length = 959
Score = 1937 bits (5018), Expect = 0.0
Identities = 959/959 (100%), Positives = 959/959 (100%)
Query: 1 MEMKLPGQEGFEASSAPRNIPSGELDSNPDPGTGPSPDGPSDTESKELGVPKDPLLFIQL 60
MEMKLPGQEGFEASSAPRNIPSGELDSNPDPGTGPSPDGPSDTESKELGVPKDPLLFIQL
Sbjct: 1 MEMKLPGQEGFEASSAPRNIPSGELDSNPDPGTGPSPDGPSDTESKELGVPKDPLLFIQL 60
Query: 61 NELLGWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLD 120
NELLGWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLD
Sbjct: 61 NELLGWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLD 120
Query: 121 CPAQSLLELVEQVTRVESLSPELRGQLQALLLQRPQHYNQTTGTRPCWGSTHPRKASDNE 180
CPAQSLLELVEQVTRVESLSPELRGQLQALLLQRPQHYNQTTGTRPCWGSTHPRKASDNE
Sbjct: 121 CPAQSLLELVEQVTRVESLSPELRGQLQALLLQRPQHYNQTTGTRPCWGSTHPRKASDNE 180
Query: 181 EAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSR 240
EAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSR
Sbjct: 181 EAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSR 240
Query: 241 FFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPP 300
FFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPP
Sbjct: 241 FFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPP 300
Query: 301 GRWDPTARIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGR 360
GRWDPTARIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGR
Sbjct: 301 GRWDPTARIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGR 360
Query: 361 LFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGV 420
LFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGV
Sbjct: 361 LFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGV 420
Query: 421 LESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWV 480
LESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWV
Sbjct: 421 LESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWV 480
Query: 481 ATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGSSAY 540
ATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGSSAY
Sbjct: 481 ATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGSSAY 540
Query: 541 GCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCHTV 600
GCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCHTV
Sbjct: 541 GCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCHTV 600
Query: 601 PDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLA 660
PDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLA
Sbjct: 601 PDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLA 660
Query: 661 TPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRM 720
TPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRM
Sbjct: 661 TPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRM 720
Query: 721 EYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPN 780
EYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPN
Sbjct: 721 EYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPN 780
Query: 781 FLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLL 840
FLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLL
Sbjct: 781 FLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLL 840
Query: 841 LMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKA 900
LMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKA
Sbjct: 841 LMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKA 900
Query: 901 LERVFSPQELLWLDELMPEEERSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN 959
LERVFSPQELLWLDELMPEEERSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN
Sbjct: 901 LERVFSPQELLWLDELMPEEERSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN 959
>gi|4507025 solute carrier family 4, sodium bicarbonate cotransporter,
member 4 isoform 2 [Homo sapiens]
Length = 1035
Score = 942 bits (2436), Expect = 0.0
Identities = 504/953 (52%), Positives = 656/953 (68%), Gaps = 49/953 (5%)
Query: 51 PKDPLLFIQLNELLGWP-QALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLR 109
P P LF +L+ELL Q +EW+ET RW+ FEEK+E RWS PHV TL+L SL +LR
Sbjct: 59 PAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELR 118
Query: 110 SLLAEGLVLLDCPAQSLLELVEQVT--RVES--LSPELRGQLQALLLQRPQHYNQTTG-- 163
+ + +G ++LD A SL +LVE + ++E+ L PEL+ ++ LL++ +H + +
Sbjct: 119 TCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLR 178
Query: 164 ----------------TRPCWGS---THPRKAS----DNEEAPLREQCQNPLRQKLPPGA 200
T P GS TH S D + P ++Q +N +KLP A
Sbjct: 179 SLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDA 238
Query: 201 EAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGR 260
EA VL GE+ FL P AFVRL+ V+LG+LTEV +P+RF +LLGP K YHE+GR
Sbjct: 239 EASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGR 298
Query: 261 AAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHK 320
A A L+SD F +A + HDL+A +D FL+EV VLPPG WDP RI PPK LPS K
Sbjct: 299 AIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDK 358
Query: 321 RLP----SQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWY 376
R + ++ G T + H G H ELQRTGR GGLI+D++RK P++
Sbjct: 359 RKNMYSGGENVQMNGD-----TPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFF 413
Query: 377 PSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCL 436
SDF DAL++Q SA+L+IYLATVTNAITFGGLLGDATD QGVLESFLGTAV+GA FCL
Sbjct: 414 ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 473
Query: 437 MAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLV 496
AGQPLTILSSTGPVLVFERLLF+FS+D + DYL FRLW+G+W A CL+LVAT+AS LV
Sbjct: 474 FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 533
Query: 497 RYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPG-SSAYGCLCQYPGPGG- 551
+YFTRFTEEGF +LIS IFIYDA KM+ L YPI K G ++ + C C P P
Sbjct: 534 QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 593
Query: 552 NESQWIRTRPKDRDDIVSMDL---GLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSL 608
+ S P+ + S D+ + + L EC++ GG+ G C+ VPDI S
Sbjct: 594 SISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSF 653
Query: 609 LLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPR 668
+LFL ++ +MALK KTS +FP+ RK +SDF+ +L+IL+ C +DA +G+ TPKL+VP
Sbjct: 654 ILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPS 713
Query: 669 EFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGA 728
EFKPT P RGW V PFG NPWW +AAA+PALL++ILIFMDQQITAVI+NR E++L+KGA
Sbjct: 714 EFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGA 773
Query: 729 GFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQR 788
G+HLDLF VA+LM++ S + LPWYV+ATVIS+AH+DSL+ E+ APGE+P FLG+REQR
Sbjct: 774 GYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQR 833
Query: 789 LTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQP 848
+TG +VFILTG S+F+AP+LKFIPMPVLYG+FLYMGVA+L+ +QF +R+KLLLMP KHQP
Sbjct: 834 VTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQP 893
Query: 849 DLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQ 908
D + LRHVPL RVHLFT +Q+ CL LLWI+KST AAIIFP+M+L LV VRK ++ +FS
Sbjct: 894 DFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQH 953
Query: 909 ELLWLDELMPEEE--RSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN 959
+L +LD+++PE++ + EK + + SD++DS+ Y K P I I ++
Sbjct: 954 DLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMD 1006
>gi|148596928 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 1 [Homo sapiens]
Length = 1079
Score = 942 bits (2436), Expect = 0.0
Identities = 504/953 (52%), Positives = 656/953 (68%), Gaps = 49/953 (5%)
Query: 51 PKDPLLFIQLNELLGWP-QALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLR 109
P P LF +L+ELL Q +EW+ET RW+ FEEK+E RWS PHV TL+L SL +LR
Sbjct: 103 PAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELR 162
Query: 110 SLLAEGLVLLDCPAQSLLELVEQVT--RVES--LSPELRGQLQALLLQRPQHYNQTTG-- 163
+ + +G ++LD A SL +LVE + ++E+ L PEL+ ++ LL++ +H + +
Sbjct: 163 TCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLR 222
Query: 164 ----------------TRPCWGS---THPRKAS----DNEEAPLREQCQNPLRQKLPPGA 200
T P GS TH S D + P ++Q +N +KLP A
Sbjct: 223 SLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDA 282
Query: 201 EAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGR 260
EA VL GE+ FL P AFVRL+ V+LG+LTEV +P+RF +LLGP K YHE+GR
Sbjct: 283 EASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGR 342
Query: 261 AAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHK 320
A A L+SD F +A + HDL+A +D FL+EV VLPPG WDP RI PPK LPS K
Sbjct: 343 AIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDK 402
Query: 321 RLP----SQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWY 376
R + ++ G T + H G H ELQRTGR GGLI+D++RK P++
Sbjct: 403 RKNMYSGGENVQMNGD-----TPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFF 457
Query: 377 PSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCL 436
SDF DAL++Q SA+L+IYLATVTNAITFGGLLGDATD QGVLESFLGTAV+GA FCL
Sbjct: 458 ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 517
Query: 437 MAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLV 496
AGQPLTILSSTGPVLVFERLLF+FS+D + DYL FRLW+G+W A CL+LVAT+AS LV
Sbjct: 518 FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 577
Query: 497 RYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPG-SSAYGCLCQYPGPGG- 551
+YFTRFTEEGF +LIS IFIYDA KM+ L YPI K G ++ + C C P P
Sbjct: 578 QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 637
Query: 552 NESQWIRTRPKDRDDIVSMDL---GLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSL 608
+ S P+ + S D+ + + L EC++ GG+ G C+ VPDI S
Sbjct: 638 SISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSF 697
Query: 609 LLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPR 668
+LFL ++ +MALK KTS +FP+ RK +SDF+ +L+IL+ C +DA +G+ TPKL+VP
Sbjct: 698 ILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPS 757
Query: 669 EFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGA 728
EFKPT P RGW V PFG NPWW +AAA+PALL++ILIFMDQQITAVI+NR E++L+KGA
Sbjct: 758 EFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGA 817
Query: 729 GFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQR 788
G+HLDLF VA+LM++ S + LPWYV+ATVIS+AH+DSL+ E+ APGE+P FLG+REQR
Sbjct: 818 GYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQR 877
Query: 789 LTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQP 848
+TG +VFILTG S+F+AP+LKFIPMPVLYG+FLYMGVA+L+ +QF +R+KLLLMP KHQP
Sbjct: 878 VTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQP 937
Query: 849 DLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQ 908
D + LRHVPL RVHLFT +Q+ CL LLWI+KST AAIIFP+M+L LV VRK ++ +FS
Sbjct: 938 DFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQH 997
Query: 909 ELLWLDELMPEEE--RSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN 959
+L +LD+++PE++ + EK + + SD++DS+ Y K P I I ++
Sbjct: 998 DLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMD 1050
>gi|197927160 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 3 [Homo sapiens]
Length = 1094
Score = 932 bits (2409), Expect = 0.0
Identities = 496/936 (52%), Positives = 646/936 (69%), Gaps = 47/936 (5%)
Query: 51 PKDPLLFIQLNELLGWP-QALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLR 109
P P LF +L+ELL Q +EW+ET RW+ FEEK+E RWS PHV TL+L SL +LR
Sbjct: 103 PAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELR 162
Query: 110 SLLAEGLVLLDCPAQSLLELVEQVT--RVES--LSPELRGQLQALLLQRPQHYNQTTG-- 163
+ + +G ++LD A SL +LVE + ++E+ L PEL+ ++ LL++ +H + +
Sbjct: 163 TCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLR 222
Query: 164 ----------------TRPCWGS---THPRKAS----DNEEAPLREQCQNPLRQKLPPGA 200
T P GS TH S D + P ++Q +N +KLP A
Sbjct: 223 SLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDA 282
Query: 201 EAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGR 260
EA VL GE+ FL P AFVRL+ V+LG+LTEV +P+RF +LLGP K YHE+GR
Sbjct: 283 EASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGR 342
Query: 261 AAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHK 320
A A L+SD F +A + HDL+A +D FL+EV VLPPG WDP RI PPK LPS K
Sbjct: 343 AIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDK 402
Query: 321 RLP----SQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWY 376
R + ++ G T + H G H ELQRTGR GGLI+D++RK P++
Sbjct: 403 RKNMYSGGENVQMNGD-----TPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFF 457
Query: 377 PSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCL 436
SDF DAL++Q SA+L+IYLATVTNAITFGGLLGDATD QGVLESFLGTAV+GA FCL
Sbjct: 458 ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 517
Query: 437 MAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLV 496
AGQPLTILSSTGPVLVFERLLF+FS+D + DYL FRLW+G+W A CL+LVAT+AS LV
Sbjct: 518 FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 577
Query: 497 RYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPG-SSAYGCLCQYPGPGG- 551
+YFTRFTEEGF +LIS IFIYDA KM+ L YPI K G ++ + C C P P
Sbjct: 578 QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 637
Query: 552 NESQWIRTRPKDRDDIVSMDL---GLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSL 608
+ S P+ + S D+ + + L EC++ GG+ G C+ VPDI S
Sbjct: 638 SISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSF 697
Query: 609 LLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPR 668
+LFL ++ +MALK KTS +FP+ RK +SDF+ +L+IL+ C +DA +G+ TPKL+VP
Sbjct: 698 ILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPS 757
Query: 669 EFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGA 728
EFKPT P RGW V PFG NPWW +AAA+PALL++ILIFMDQQITAVI+NR E++L+KGA
Sbjct: 758 EFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGA 817
Query: 729 GFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQR 788
G+HLDLF VA+LM++ S + LPWYV+ATVIS+AH+DSL+ E+ APGE+P FLG+REQR
Sbjct: 818 GYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQR 877
Query: 789 LTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQP 848
+TG +VFILTG S+F+AP+LKFIPMPVLYG+FLYMGVA+L+ +QF +R+KLLLMP KHQP
Sbjct: 878 VTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQP 937
Query: 849 DLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQ 908
D + LRHVPL RVHLFT +Q+ CL LLWI+KST AAIIFP+M+L LV VRK ++ +FS
Sbjct: 938 DFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQH 997
Query: 909 ELLWLDELMPEEERSIPEKGLEPEHSFSGSDSEDSE 944
+L +LD+++PE+++ E + + DS++ +
Sbjct: 998 DLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDD 1033
>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
Length = 1121
Score = 852 bits (2201), Expect = 0.0
Identities = 466/977 (47%), Positives = 607/977 (62%), Gaps = 86/977 (8%)
Query: 35 PSPDGPSDTESKELGVPKDPLLFIQLNELLGWPQALEWRETGRWVLFEEKLEVAAGRWSA 94
P+ + D +E P +P LF +++ L +EW+E+ RW+ FEEK+E RWS
Sbjct: 93 PAAEQLQDILGEEDEAP-NPTLFTEMDTLQHDGDQMEWKESARWIKFEEKVEEGGERWSK 151
Query: 95 PHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVES----LSPELRGQLQAL 150
PHV TL+L SL +LR+ L G VLLD + SL ++++ V + L PELR ++ +
Sbjct: 152 PHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYV 211
Query: 151 LLQRPQHYNQ---------------TTGTRPCWG-----STH------------------ 172
LL+R +H + TT P S H
Sbjct: 212 LLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSANYGRLC 271
Query: 173 ---PRKASDNEEAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVL 229
R +D P +Q +N +K+P +EA VL GE+ FL QP AFVRL +L
Sbjct: 272 HAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAML 331
Query: 230 GSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALD 289
G +TEV +P+RF +LLGP K Y+E+GRA A L+ D F +A N DL+A +D
Sbjct: 332 GGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGID 391
Query: 290 AFLEEVTVLPPGRWDPTARIPPPKCLPSQHKR--------LPSQQREIRGPA-------- 333
FL+EV VLPPG WDP RI PPK +PS KR L + G
Sbjct: 392 EFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNG 451
Query: 334 ---------------VPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPS 378
+S +D H EL TGR FGGL D++RK+PW+PS
Sbjct: 452 GGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPS 511
Query: 379 DFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMA 438
DF D H+Q SA+L+IYL +TNAITFGGLLGDATD QGV+ESFLGTA+AG+ FCL +
Sbjct: 512 DFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFS 571
Query: 439 GQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRY 498
GQPL ILSSTGP+L+FE+LLF FS+ LDY+ FRLW+G+ A CL+LVAT+AS +++Y
Sbjct: 572 GQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKY 631
Query: 499 FTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPGS-SAYGCLCQYPGPGGNES 554
TRFTEEGF LIS IFIYDA+ KM+ YPI KP + Y C C P N +
Sbjct: 632 ITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTV-NTT 690
Query: 555 QWIRTRPKDRDDIVSM----DLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLL 610
+ + P D S+ +L ++ SLL EC GG G C +PD+A S +L
Sbjct: 691 VFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMSFIL 750
Query: 611 FLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREF 670
F ++ + LK K SR+FP+ VR ++DFS V +IL+ CG+DA GL TPKL VP
Sbjct: 751 FFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVPSVI 810
Query: 671 KPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGF 730
KPT P RGW V+PFG NPWW A+ LPALL++ILIFMDQQITAVI+NR E +L+K AG+
Sbjct: 811 KPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGY 870
Query: 731 HLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLT 790
HLDLF V +LM L S +GLPWYV+ATVIS+AH+DSL+ E+ APGE+P FLG+REQR+T
Sbjct: 871 HLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVT 930
Query: 791 GLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPDL 850
G++VFILTG S+FLAP+LK IP+PVLYG+FLYMGVA+L+ IQF R KL LMPAKHQPD
Sbjct: 931 GIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQFWERCKLFLMPAKHQPDH 990
Query: 851 LLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQEL 910
LRHVPL R+HLFT +Q+ CL +LWI+KST AAIIFP+M+LGL+ VR+ L+ +FS +L
Sbjct: 991 AFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDL 1050
Query: 911 LWLDELMPEEERSIPEK 927
W+D ++PE+E+ +K
Sbjct: 1051 AWIDNILPEKEKKETDK 1067
>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
sapiens]
Length = 1137
Score = 842 bits (2174), Expect = 0.0
Identities = 466/993 (46%), Positives = 607/993 (61%), Gaps = 102/993 (10%)
Query: 35 PSPDGPSDTESKELGVPKDPLLFIQLNELLGWPQALEWRETGRWVLFEEKLEVAAGRWSA 94
P+ + D +E P +P LF +++ L +EW+E+ RW+ FEEK+E RWS
Sbjct: 93 PAAEQLQDILGEEDEAP-NPTLFTEMDTLQHDGDQMEWKESARWIKFEEKVEEGGERWSK 151
Query: 95 PHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVES----LSPELRGQLQAL 150
PHV TL+L SL +LR+ L G VLLD + SL ++++ V + L PELR ++ +
Sbjct: 152 PHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVSYV 211
Query: 151 LLQRPQHYNQ---------------TTGTRPCWG-----STH------------------ 172
LL+R +H + TT P S H
Sbjct: 212 LLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSANYGRLC 271
Query: 173 ---PRKASDNEEAPLREQCQNPLRQKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVL 229
R +D P +Q +N +K+P +EA VL GE+ FL QP AFVRL +L
Sbjct: 272 HAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSAML 331
Query: 230 GSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALD 289
G +TEV +P+RF +LLGP K Y+E+GRA A L+ D F +A N DL+A +D
Sbjct: 332 GGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAGID 391
Query: 290 AFLEEVTVLPPGRWDPTARIPPPKCLPSQHKR--------LPSQQREIRGPA-------- 333
FL+EV VLPPG WDP RI PPK +PS KR L + G
Sbjct: 392 EFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGGNG 451
Query: 334 ---------------VPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPS 378
+S +D H EL TGR FGGL D++RK+PW+PS
Sbjct: 452 GGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWFPS 511
Query: 379 DFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMA 438
DF D H+Q SA+L+IYL +TNAITFGGLLGDATD QGV+ESFLGTA+AG+ FCL +
Sbjct: 512 DFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCLFS 571
Query: 439 GQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRY 498
GQPL ILSSTGP+L+FE+LLF FS+ LDY+ FRLW+G+ A CL+LVAT+AS +++Y
Sbjct: 572 GQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFIIKY 631
Query: 499 FTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPGS-SAYGCLCQYPGPGGNES 554
TRFTEEGF LIS IFIYDA+ KM+ YPI KP + Y C C P N +
Sbjct: 632 ITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTV-NTT 690
Query: 555 QWIRTRPKDRDDIVSM----DLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLL 610
+ + P D S+ +L ++ SLL EC GG G C +PD+A S +L
Sbjct: 691 VFNASAPLAPDTNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMSFIL 750
Query: 611 FLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREF 670
F ++ + LK K SR+FP+ VR ++DFS V +IL+ CG+DA GL TPKL VP
Sbjct: 751 FFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVPSVI 810
Query: 671 KPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGF 730
KPT P RGW V+PFG NPWW A+ LPALL++ILIFMDQQITAVI+NR E +L+K AG+
Sbjct: 811 KPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKAAGY 870
Query: 731 HLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLT 790
HLDLF V +LM L S +GLPWYV+ATVIS+AH+DSL+ E+ APGE+P FLG+REQR+T
Sbjct: 871 HLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQRVT 930
Query: 791 GLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQ----------------FT 834
G++VFILTG S+FLAP+LK IP+PVLYG+FLYMGVA+L+ IQ F
Sbjct: 931 GIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLTPFW 990
Query: 835 NRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGL 894
R KL LMPAKHQPD LRHVPL R+HLFT +Q+ CL +LWI+KST AAIIFP+M+LGL
Sbjct: 991 ERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGL 1050
Query: 895 VGVRKALERVFSPQELLWLDELMPEEERSIPEK 927
+ VR+ L+ +FS +L W+D ++PE+E+ +K
Sbjct: 1051 IIVRRLLDFIFSQHDLAWIDNILPEKEKKETDK 1083
>gi|90403614 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform a [Homo sapiens]
Length = 1093
Score = 808 bits (2087), Expect = 0.0
Identities = 436/928 (46%), Positives = 592/928 (63%), Gaps = 67/928 (7%)
Query: 43 TESKELGVPKDPLLFIQLNEL-LGWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLA 101
TE E VP + LF +L+E+ + + EW+ET RW+ FEE +E RWS P+V TL+
Sbjct: 105 TEEDEEHVPHE--LFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLS 162
Query: 102 LPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVESLSPEL----RGQLQALLLQRPQH 157
L SL +LRS L G VLLD A S+ E+ + + + LS +L R +++ LL++ H
Sbjct: 163 LHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHH 222
Query: 158 YNQTTGTR-----------------PCWGSTHPRKASDNEEAPLREQCQNPLR------- 193
N+ P H + S + +N +
Sbjct: 223 QNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVD 282
Query: 194 ---------QKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCL 244
+K+P GAEA VL GE+ L +P+ AFVRL V+L LTEV +P+RF +
Sbjct: 283 LSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFI 342
Query: 245 LLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWD 304
LLGP G+ YHE+GR+ A +++D F +A DLLA +D FL++VTVLPPG WD
Sbjct: 343 LLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWD 402
Query: 305 PTARIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAE-DRHRHGPHAHSPELQRTGRLFG 363
P+ RI PPK +PSQ KR + P VP ++ HG H+ PELQRTGRLFG
Sbjct: 403 PSIRIEPPKNVPSQEKR--------KMPGVPNGNVCHIEQEPHGGHS-GPELQRTGRLFG 453
Query: 364 GLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLES 423
GL+ D++RK PWY SD+ DAL LQC ++ L++Y A ++ ITFGGLLG+AT+G +ES
Sbjct: 454 GLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIES 513
Query: 424 FLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATF 483
G ++ G A+ L AGQ LTIL STGPVLVFE++LF F +DY+L YL R +G+W A
Sbjct: 514 LFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFL 573
Query: 484 CLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPI----QKPGSSA 539
C+VLVAT+AS LV Y TRFTEE F +LI +IFIY+A+ K+++L TYPI Q S
Sbjct: 574 CIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSL 633
Query: 540 YGCLCQYP-GPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCH 598
Y C C P P + Q+ + +IV+ ++ N ++ EC G G C
Sbjct: 634 YYCRCTLPENPNNHTLQYWKDH-----NIVTAEVHWANLTV---SECQEMHGEFMGSACG 685
Query: 599 T----VPDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLD 654
PD+ F+S +LF T+F + LK KTSR+FP+ VR +SDF+ L I +D
Sbjct: 686 HHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIID 745
Query: 655 AFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITA 714
+G+ +PKL VP FKPT RGW+++P G NPWW +AA +PALL +ILIFMDQQITA
Sbjct: 746 FLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITA 805
Query: 715 VILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACA 774
VI+NR E++L+KG G+HLDL VA+++ + S +GLPW+V+ATV+S+ H++SL+ ES A
Sbjct: 806 VIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSA 865
Query: 775 PGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFT 834
PGE+P FLGIREQR+TGL++F+L G S+F+ +LKFIPMPVLYG+FLYMGV++L IQF
Sbjct: 866 PGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFF 925
Query: 835 NRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGL 894
+R+KL MPAKHQPD + LRHVPL +VHLFT IQL CL LLW+IK++PAAI+FP+M+L L
Sbjct: 926 DRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLAL 985
Query: 895 VGVRKALERVFSPQELLWLDELMPEEER 922
V VRK ++ FS +EL WLD+LMPE ++
Sbjct: 986 VFVRKVMDLCFSKRELSWLDDLMPESKK 1013
>gi|90568034 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform b [Homo sapiens]
Length = 1044
Score = 808 bits (2087), Expect = 0.0
Identities = 436/928 (46%), Positives = 592/928 (63%), Gaps = 67/928 (7%)
Query: 43 TESKELGVPKDPLLFIQLNEL-LGWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLA 101
TE E VP + LF +L+E+ + + EW+ET RW+ FEE +E RWS P+V TL+
Sbjct: 105 TEEDEEHVPHE--LFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLS 162
Query: 102 LPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVESLSPEL----RGQLQALLLQRPQH 157
L SL +LRS L G VLLD A S+ E+ + + + LS +L R +++ LL++ H
Sbjct: 163 LHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHH 222
Query: 158 YNQTTGTR-----------------PCWGSTHPRKASDNEEAPLREQCQNPLR------- 193
N+ P H + S + +N +
Sbjct: 223 QNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVD 282
Query: 194 ---------QKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCL 244
+K+P GAEA VL GE+ L +P+ AFVRL V+L LTEV +P+RF +
Sbjct: 283 LSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFI 342
Query: 245 LLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWD 304
LLGP G+ YHE+GR+ A +++D F +A DLLA +D FL++VTVLPPG WD
Sbjct: 343 LLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWD 402
Query: 305 PTARIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAE-DRHRHGPHAHSPELQRTGRLFG 363
P+ RI PPK +PSQ KR + P VP ++ HG H+ PELQRTGRLFG
Sbjct: 403 PSIRIEPPKNVPSQEKR--------KMPGVPNGNVCHIEQEPHGGHS-GPELQRTGRLFG 453
Query: 364 GLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLES 423
GL+ D++RK PWY SD+ DAL LQC ++ L++Y A ++ ITFGGLLG+AT+G +ES
Sbjct: 454 GLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIES 513
Query: 424 FLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATF 483
G ++ G A+ L AGQ LTIL STGPVLVFE++LF F +DY+L YL R +G+W A
Sbjct: 514 LFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFL 573
Query: 484 CLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPI----QKPGSSA 539
C+VLVAT+AS LV Y TRFTEE F +LI +IFIY+A+ K+++L TYPI Q S
Sbjct: 574 CIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSL 633
Query: 540 YGCLCQYP-GPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCH 598
Y C C P P + Q+ + +IV+ ++ N ++ EC G G C
Sbjct: 634 YYCRCTLPENPNNHTLQYWKDH-----NIVTAEVHWANLTV---SECQEMHGEFMGSACG 685
Query: 599 T----VPDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLD 654
PD+ F+S +LF T+F + LK KTSR+FP+ VR +SDF+ L I +D
Sbjct: 686 HHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIID 745
Query: 655 AFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITA 714
+G+ +PKL VP FKPT RGW+++P G NPWW +AA +PALL +ILIFMDQQITA
Sbjct: 746 FLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITA 805
Query: 715 VILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACA 774
VI+NR E++L+KG G+HLDL VA+++ + S +GLPW+V+ATV+S+ H++SL+ ES A
Sbjct: 806 VIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSA 865
Query: 775 PGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFT 834
PGE+P FLGIREQR+TGL++F+L G S+F+ +LKFIPMPVLYG+FLYMGV++L IQF
Sbjct: 866 PGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFF 925
Query: 835 NRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGL 894
+R+KL MPAKHQPD + LRHVPL +VHLFT IQL CL LLW+IK++PAAI+FP+M+L L
Sbjct: 926 DRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLAL 985
Query: 895 VGVRKALERVFSPQELLWLDELMPEEER 922
V VRK ++ FS +EL WLD+LMPE ++
Sbjct: 986 VFVRKVMDLCFSKRELSWLDDLMPESKK 1013
>gi|155722998 solute carrier family 4, sodium bicarbonate
transporter-like, member 10 [Homo sapiens]
Length = 1088
Score = 803 bits (2075), Expect = 0.0
Identities = 454/993 (45%), Positives = 617/993 (62%), Gaps = 74/993 (7%)
Query: 24 ELDSNPDPGT-GPSPDGPSDTESKELGVPKDPL------LFIQLNELLGWPQA--LEWRE 74
E DS + G PS D PS LG D LF +L+E+ W + EWRE
Sbjct: 78 ERDSGLEDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEIC-WREGEDAEWRE 136
Query: 75 TGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVT 134
T RW+ FEE +E RWS P+V TL+L SL +LRS + G VLLD A +L E+ + V
Sbjct: 137 TARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVL 196
Query: 135 RVE----SLSPELRGQLQALLLQRPQHYNQT--TGTRPCWGS--------THPRKASDN- 179
+ L+ ++R ++ L+++ H NQ T P S + P N
Sbjct: 197 DQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNA 256
Query: 180 ------EEAPLREQCQNPLRQ----------------KLPPGAEAGTVLAGELGFLAQPL 217
+ AP + +N + + K+PPGAEA +L GEL FL + +
Sbjct: 257 GQVVSPQSAPACVENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLDRTV 316
Query: 218 GAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRR 277
AFVRL V+L L EV +P+RF +LLGP G+ YHE+GR+ A L++D F +
Sbjct: 317 VAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYK 376
Query: 278 ASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPSQQREIRGPAVPRL 337
A + +DL++ +D FL++VTVLPPG WDP+ RI PPK +PSQ KR + PAVP
Sbjct: 377 AKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKR--------KIPAVPNG 428
Query: 338 TSAE-DRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIY 396
T+A + HG H+ PELQRTGR+FGGLI D++RK P++ SDF DA LQC ++ L++Y
Sbjct: 429 TAAHGEAEPHGGHS-GPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLY 487
Query: 397 LATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFER 456
A ++ ITFGGLLG+AT+G +ES G ++ G A+ L GQPLTIL STGPVLVFE+
Sbjct: 488 CACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEK 547
Query: 457 LLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFI 516
+LF F ++Y L YL R +G+W AT C++LVAT+AS LV Y TRFTEE F +LI +IFI
Sbjct: 548 ILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFI 607
Query: 517 YDAVGKMLNLTHTYPIQKPGS----SAYGCLCQYPG--PGGNESQWIRTRPKDRDDIVSM 570
Y+A+ K+ L+ YPI + Y C C P G +W R DI+
Sbjct: 608 YEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEW-RESNISASDIIWE 666
Query: 571 DLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLLFLTSFFFAMALKCVKTSRFF 630
+L + L R GH VPD+ F+S++LF ++ + LK KTSR+F
Sbjct: 667 NLTVSECKSLHGEYVGRACGHDHP----YVPDVLFWSVILFFSTVTLSATLKQFKTSRYF 722
Query: 631 PSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWW 690
P+ VR +SDF+ L IL +D +G+ +PKL VP FKPT RGW V+P G NPWW
Sbjct: 723 PTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWW 782
Query: 691 WSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLP 750
+AA +PALL +ILIFMDQQITAVI+NR E++L+KG G+HLDL VAV++ + S +GLP
Sbjct: 783 TVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLP 842
Query: 751 WYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKF 810
W+V+ATV+S+ H++SL+ ES APGE+P FLGIREQR+TGL++FIL G+S+F+ +LKF
Sbjct: 843 WFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKF 902
Query: 811 IPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLA 870
IPMPVLYG+FLYMG ++L IQF +R+KL MPAKHQPD + LRHVPL +VHLFT IQ++
Sbjct: 903 IPMPVLYGVFLYMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMS 962
Query: 871 CLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQELLWLDELMPE-EERSIPEKGL 929
CLGLLWIIK + AAI+FP+M+L LV VRK ++ +F+ +EL WLD+LMPE +++ + +
Sbjct: 963 CLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEK 1022
Query: 930 EPEHSFSGSDSEDS-----ELMYQPKAPEINIS 957
E E S + E + E Y+ INIS
Sbjct: 1023 EEEQSMLAMEDEGTVQLPLEGHYRDDPSVINIS 1055
>gi|134288865 solute carrier family 4, sodium bicarbonate
cotransporter, member 7 [Homo sapiens]
Length = 1214
Score = 745 bits (1923), Expect = 0.0
Identities = 385/765 (50%), Positives = 523/765 (68%), Gaps = 32/765 (4%)
Query: 194 QKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGK 253
+K+P GAEA VL GE+ FL +P+ AFVRL V+L LTEV +P+RF LLLGP
Sbjct: 420 RKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAP 479
Query: 254 GYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPK 313
YHE+GR+ A L++D F +A + +DLL+ +D FL++VTVLPPG WDP+ RI PPK
Sbjct: 480 QYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPK 539
Query: 314 CLPSQHKRLPSQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKV 373
+PSQ KR P + T E H GP ELQRTGRLFGGLI D++RK
Sbjct: 540 SVPSQEKRKIPVFHNGSTPTLGE-TPKEAAHHAGP-----ELQRTGRLFGGLILDIKRKA 593
Query: 374 PWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAA 433
P++ SDF DAL LQC +++L++Y A ++ ITFGGLLG+AT+G +ES G ++ G A
Sbjct: 594 PFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIA 653
Query: 434 FCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEAS 493
+ L AGQPLTIL STGPVLVFE++L+ F RDY L YL R +G+W + C+VLVAT+AS
Sbjct: 654 YSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDAS 713
Query: 494 VLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGS----SAYGCLCQYPGP 549
LV Y TRFTEE F ALI +IFIY+A+ K+ +L TY + ++Y C+C P
Sbjct: 714 SLVCYITRFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPN 773
Query: 550 GGNES--QWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCHT----VPDI 603
NE+ QW +D+I + ++ N ++ EC + G G C +PD+
Sbjct: 774 PSNETLAQW------KKDNITAHNISWRNLTV---SECKKLRGVFLGSACGHHGPYIPDV 824
Query: 604 AFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPK 663
F+ ++LF T+FF + LK KT R+FP+ VR +SDF+ L I++ +D +G+ +PK
Sbjct: 825 LFWCVILFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPK 884
Query: 664 LMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYR 723
L VP +F+PT P RGW++SP G NPWW + AA+PALL +ILIFMDQQITAVI+NR E++
Sbjct: 885 LHVPEKFEPTHPERGWIISPLGDNPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHK 944
Query: 724 LQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLG 783
L+KGAG+HLDL V V++ + S +GLPW+V+ATV+S++H++SL+ ES APGE+P FLG
Sbjct: 945 LKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLG 1004
Query: 784 IREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMP 843
IREQR+TGL++FIL G S+F+ VLKFIPMPVLYG+FLYMGV++L IQ +R+KL MP
Sbjct: 1005 IREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMP 1064
Query: 844 AKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALER 903
AKHQPDL+ LR+VPL +VH+FT IQL CL LLW+IK + AA++FP+M+L LV VRK ++
Sbjct: 1065 AKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDL 1124
Query: 904 VFSPQELLWLDELMPEEERSIPEKGLEPEHSFSGSDSEDSELMYQ 948
F+ +EL WLD+LMPE ++ + E + E++E M Q
Sbjct: 1125 CFTKRELSWLDDLMPESKK-------KKEDDKKKKEKEEAERMLQ 1162
Score = 75.1 bits (183), Expect = 3e-13
Identities = 51/142 (35%), Positives = 71/142 (50%), Gaps = 11/142 (7%)
Query: 30 DPGTGPSPDGPSDTESKELGVPKDPL------LFIQLNELLGWP-QALEWRETGRWVLFE 82
D PS D PS LG D LF +++EL + EW+ET RW+ FE
Sbjct: 80 DGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFE 139
Query: 83 EKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQV----TRVES 138
E +E RWS P+V TL+L SL +LRS + G V+LD A +L E+ + V
Sbjct: 140 EDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQ 199
Query: 139 LSPELRGQLQALLLQRPQHYNQ 160
L +R ++ LL+R H N+
Sbjct: 200 LDESIRENVREALLKRHHHQNE 221
>gi|156071474 solute carrier family 4, anion exchanger, member 2
(erythrocyte membrane protein band 3-like 1) [Homo
sapiens]
Length = 1241
Score = 577 bits (1487), Expect = e-164
Identities = 375/968 (38%), Positives = 522/968 (53%), Gaps = 110/968 (11%)
Query: 15 SAPRNIPSGELDSNPDPGTGPSPDGPSDTESKELGVPKDPLLFIQLNELL-GWPQALEWR 73
+A + SG P P P P K +F++LNELL Q +WR
Sbjct: 292 NAKGSTQSGREGREPGPTPRARPRAPH----------KPHEVFVELNELLLDKNQEPQWR 341
Query: 74 ETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQV 133
ET RW+ FEE +E RW PHV +L+ SL +LR LA G VLLD Q+L + QV
Sbjct: 342 ETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQV 401
Query: 134 TRVESLSPELRGQ-----LQALLLQRPQ------------------------HYNQTTG- 163
+S +++ + L+ALLL+ H+ Q
Sbjct: 402 VEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSFPRNISAGSLGSLLGHHHGQGAES 461
Query: 164 ----TRPCWGSTHPRKASDNEEAPL----------REQCQNPLR--QKLPPGAEAGTVLA 207
T P G + E L R + ++ L+ +K+P AEA VL
Sbjct: 462 DPHVTEPLMGGVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLV 521
Query: 208 GELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLS 267
G + FL++P AFVRLR V L ++ EV +P RF LLLGP YHE+GR+ + L+S
Sbjct: 522 GCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMS 581
Query: 268 DPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPS--QHKRLPSQ 325
D QF + A DLL A++AFL+ VLPP + + + L S +R +
Sbjct: 582 DKQFHEAAYLADEREDLLTAINAFLDCSVVLPP------SEVQGEELLRSVAHFQRQMLK 635
Query: 326 QREIRGPAVP-----RLTSAEDRH-----RHGPHAHSPELQRTGRLFGGLIQDVRRKVPW 375
+RE +G +P SA+D+ A L+RTGR FGGLI+DVRR+ P
Sbjct: 636 KREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRPFGGLIRDVRRRYPH 695
Query: 376 YPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFC 435
Y SDF DAL QC +AV++IY A ++ AITFGGLLG+ T GV E + TA+ G FC
Sbjct: 696 YLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVVFC 755
Query: 436 LMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVL 495
L+ QPL ++ +GP+LVFE FSF L+YL R+W+G W+ L++VA E S L
Sbjct: 756 LLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFL 815
Query: 496 VRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGSSAYGCLCQYPGP--GGNE 553
VR+ +RFT+E F LISLIFIY+ K++ + +P+ +GC GG
Sbjct: 816 VRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPL-------HGCSASNSSEVDGGEN 868
Query: 554 SQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQG-GHPRGPGCHTVPDIAFFSLLLFL 612
W RP LG N SL + G G PRG P+ A SL+L
Sbjct: 869 MTWAGARPT---------LGPGNRSL-----AGQSGQGKPRGQ-----PNTALLSLVLMA 909
Query: 613 TSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFL-GLATPKLMVPREFK 671
+FF A L+ K SRFFP +R+ + DF +AIL+ +D + T KL VP F
Sbjct: 910 GTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIEDTYTQKLSVPSGFS 969
Query: 672 PTLPG-RGWLVSPFGAN---PWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKG 727
T P RGW+++P G P W VA+ LPA+L+ ILIFM+ QIT +I+++ E LQKG
Sbjct: 970 VTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITTLIISKKERMLQKG 1029
Query: 728 AGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQ 787
+GFHLDL + + + + GLPW +ATV S+ H ++L S+A APG++P ++EQ
Sbjct: 1030 SGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPKIQEVKEQ 1089
Query: 788 RLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQ 847
R+TGL+V +L G SI + +L+ IP+ VL+GIFLYMGV +L+ IQF R+ LLLMP KH
Sbjct: 1090 RVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHH 1149
Query: 848 PDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRK-ALERVFS 906
PD+ ++ V R+HLFTA+QL CL LLW + ST A++ FP +L+ V +R L R+F+
Sbjct: 1150 PDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFT 1209
Query: 907 PQELLWLD 914
+E+ LD
Sbjct: 1210 DREMKCLD 1217
>gi|157671951 solute carrier family 4, anion exchanger, member 3
isoform 1 [Homo sapiens]
Length = 1232
Score = 557 bits (1436), Expect = e-158
Identities = 362/924 (39%), Positives = 494/924 (53%), Gaps = 100/924 (10%)
Query: 56 LFIQLNEL-LGWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAE 114
+F++LNEL L Q WRET RW+ FEE +E RW PHV +L+ SL +LR +A
Sbjct: 321 VFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAH 380
Query: 115 GLVLLDCPAQSLLEL----VEQVTRVESLSPELRGQLQALLLQRPQHYNQ---------- 160
G LLD +L + VE + + + PE R + LL + H N
Sbjct: 381 GAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRN 440
Query: 161 --TTGTRPCWGSTHPRKASD------------NEEAPL----REQCQNPLR--------- 193
++ G+ HP + E APL + + PL
Sbjct: 441 PSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGDGHRG 500
Query: 194 ------QKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLG 247
+K+P AEA VL G + FL QP AFVRL V+L S+ EV +P RF ++LG
Sbjct: 501 KSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLG 560
Query: 248 PCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTA 307
P YHE+GR+ A L+SD F + +A + DLL+A+ FL+ V+PP +
Sbjct: 561 PSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEGRD 620
Query: 308 RIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSA-------EDRHRHGPHAHSPE---LQR 357
+ + + + + L ++RE V T E G +PE L R
Sbjct: 621 LL---RSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDPLLR 677
Query: 358 TGRLFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGA 417
TG +FGGL++DVRR+ P YPSD DALH QC +AVL+IY A ++ AITFGGLLG+ T+G
Sbjct: 678 TGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGL 737
Query: 418 QGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVG 477
GV E + TAV G F L+ QPL ++ +GP+LVFE F F R L+YL R+WVG
Sbjct: 738 MGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVG 797
Query: 478 IWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGS 537
+W+ F L LVA E S LVRY + FT+E F LISLIFIY+ K+ + +P+
Sbjct: 798 LWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPL----- 852
Query: 538 SAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLI-NASLLPPPECTRQGGHPRGPG 596
L YP G E S+D GL N S LPP E P
Sbjct: 853 -----LPFYPPEGALEG--------------SLDAGLEPNGSALPPTEGP--------PS 885
Query: 597 CHTVPDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLD-A 655
P+ A SL+L L +FF A L+ + SRF R+ + DF ++IL+ +D +
Sbjct: 886 PRNQPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYS 945
Query: 656 FLGLATPKLMVPREFKPTLPG-RGWLVSPFGAN---PWWWSVAAALPALLLSILIFMDQQ 711
T KL VP T P R W + P G+ P W VAAA+PALL+ ILIFM+ Q
Sbjct: 946 ITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQ 1005
Query: 712 ITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESR 771
ITA+I+++ RL KG+GFHLDL + L L GLPW +ATV S+ H+++L
Sbjct: 1006 ITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRT 1065
Query: 772 ACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSI 831
A APG++P +REQR+TG+++ L G SI + VL+ IP+ VL+GIFLYMGV +LS I
Sbjct: 1066 AIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGI 1125
Query: 832 QFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLML 891
Q + R+ L+LMPAKH P+ + V R+HLFT IQL C+ LLW++KST A++ FP +L
Sbjct: 1126 QLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLL 1185
Query: 892 LGLVGVRKA-LERVFSPQELLWLD 914
L V +R L R+F +EL LD
Sbjct: 1186 LLTVPLRHCLLPRLFQDRELQALD 1209
>gi|157671953 solute carrier family 4, anion exchanger, member 3
isoform 2 [Homo sapiens]
Length = 1259
Score = 557 bits (1436), Expect = e-158
Identities = 362/924 (39%), Positives = 494/924 (53%), Gaps = 100/924 (10%)
Query: 56 LFIQLNEL-LGWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLAE 114
+F++LNEL L Q WRET RW+ FEE +E RW PHV +L+ SL +LR +A
Sbjct: 348 VFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTIAH 407
Query: 115 GLVLLDCPAQSLLEL----VEQVTRVESLSPELRGQLQALLLQRPQHYNQ---------- 160
G LLD +L + VE + + + PE R + LL + H N
Sbjct: 408 GAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFFPRN 467
Query: 161 --TTGTRPCWGSTHPRKASD------------NEEAPL----REQCQNPLR--------- 193
++ G+ HP + E APL + + PL
Sbjct: 468 PSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGDGHRG 527
Query: 194 ------QKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLG 247
+K+P AEA VL G + FL QP AFVRL V+L S+ EV +P RF ++LG
Sbjct: 528 KSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLFVMLG 587
Query: 248 PCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTA 307
P YHE+GR+ A L+SD F + +A + DLL+A+ FL+ V+PP +
Sbjct: 588 PSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEVEGRD 647
Query: 308 RIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSA-------EDRHRHGPHAHSPE---LQR 357
+ + + + + L ++RE V T E G +PE L R
Sbjct: 648 LL---RSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDPLLR 704
Query: 358 TGRLFGGLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGA 417
TG +FGGL++DVRR+ P YPSD DALH QC +AVL+IY A ++ AITFGGLLG+ T+G
Sbjct: 705 TGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKTEGL 764
Query: 418 QGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVG 477
GV E + TAV G F L+ QPL ++ +GP+LVFE F F R L+YL R+WVG
Sbjct: 765 MGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRVWVG 824
Query: 478 IWVATFCLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQKPGS 537
+W+ F L LVA E S LVRY + FT+E F LISLIFIY+ K+ + +P+
Sbjct: 825 LWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPL----- 879
Query: 538 SAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMDLGLI-NASLLPPPECTRQGGHPRGPG 596
L YP G E S+D GL N S LPP E P
Sbjct: 880 -----LPFYPPEGALEG--------------SLDAGLEPNGSALPPTEGP--------PS 912
Query: 597 CHTVPDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLD-A 655
P+ A SL+L L +FF A L+ + SRF R+ + DF ++IL+ +D +
Sbjct: 913 PRNQPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVLVDYS 972
Query: 656 FLGLATPKLMVPREFKPTLPG-RGWLVSPFGAN---PWWWSVAAALPALLLSILIFMDQQ 711
T KL VP T P R W + P G+ P W VAAA+PALL+ ILIFM+ Q
Sbjct: 973 ITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIFMETQ 1032
Query: 712 ITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESR 771
ITA+I+++ RL KG+GFHLDL + L L GLPW +ATV S+ H+++L
Sbjct: 1033 ITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALTVMRT 1092
Query: 772 ACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSI 831
A APG++P +REQR+TG+++ L G SI + VL+ IP+ VL+GIFLYMGV +LS I
Sbjct: 1093 AIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTSLSGI 1152
Query: 832 QFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLML 891
Q + R+ L+LMPAKH P+ + V R+HLFT IQL C+ LLW++KST A++ FP +L
Sbjct: 1153 QLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAFPFLL 1212
Query: 892 LGLVGVRKA-LERVFSPQELLWLD 914
L V +R L R+F +EL LD
Sbjct: 1213 LLTVPLRHCLLPRLFQDRELQALD 1236
>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
sapiens]
Length = 911
Score = 496 bits (1277), Expect = e-140
Identities = 320/889 (35%), Positives = 480/889 (53%), Gaps = 88/889 (9%)
Query: 56 LFIQLNELL--GWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLRSLLA 113
++++L EL+ Q L W E RWV EE L G W PH+ L SL +LR +
Sbjct: 57 VYVELQELVMDEKNQELRWMEAARWVQLEENLG-ENGAWGRPHLSHLTFWSLLELRRVFT 115
Query: 114 EGLVLLDCPAQSLL----ELVEQVTRVESLSPELRGQLQALLLQRPQHYNQTT---GTRP 166
+G VLLD SL +L+++ + + P+ R +L LL + H + G +P
Sbjct: 116 KGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKP 175
Query: 167 C--WGSTHPRKASDNEEAPLREQ--CQ-----------NPLRQKLPPGAEAGTVLAGELG 211
S P + + + L Q C+ + + +K+PP +EA VL G
Sbjct: 176 AVLTRSGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGRAD 235
Query: 212 FLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGRAAAVLLSDPQF 271
FL QP+ FVRL+ L ++ E+ +P RF +LLGP Y ++GRAAA L+S+ F
Sbjct: 236 FLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVF 294
Query: 272 QWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHKRLPSQQREIRG 331
+ A + +LL +L+ FL+ VLPP D + +P Q + L ++R
Sbjct: 295 RIDAYMAQSRGELLHSLEGFLDCSLVLPPT--DAPSEQALLSLVPVQRELL--RRRYQSS 350
Query: 332 PAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALHLQCFSA 391
PA P + + +G LQ+TG+LFGGL++D+RR+ P+Y SD DA Q +A
Sbjct: 351 PAKPDSSFYKGLDLNG--GPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAA 408
Query: 392 VLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQPLTILSSTGPV 451
V++IY A ++ AITFGGLLG+ T GV E + TAV G F L+ QPL ++ +GP+
Sbjct: 409 VIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPL 468
Query: 452 LVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFTRFTEEGFCALI 511
LVFE FSF L+Y+ R+W+G W+ +++VA E S LVR+ +R+T+E F LI
Sbjct: 469 LVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLI 528
Query: 512 SLIFIYDAVGKMLNLTHTYPIQKPGSSAYGCLCQYPGPGGNESQWIRTRPKDRDDIVSMD 571
SLIFIY+ K++ + +P+QK
Sbjct: 529 SLIFIYETFSKLIKIFQDHPLQK------------------------------------- 551
Query: 572 LGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLLFLTSFFFAMALKCVKTSRFFP 631
N ++L P+ P+GP +P+ A SL+L +FFFAM L+ K S +FP
Sbjct: 552 --TYNYNVLMVPK-------PQGP----LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFP 598
Query: 632 SVVRKGLSDFSSVLAILLGCGLDAFL-GLATPKLMVPREFK-PTLPGRGWLVSPFGAN-- 687
+R+ + DF ++IL+ +D F+ T KL VP FK RGW++ P G
Sbjct: 599 GKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSE 658
Query: 688 -PWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGAGFHLDLFCVAVLMLLTSA 746
P W A+ALPALL+ ILIF++ QIT +I+++ E ++ KG+GFHLDL V + + +
Sbjct: 659 FPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAAL 718
Query: 747 LGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAP 806
G+PW + TV S+ H ++L +A PG ++EQR++GL+V +L G SI + P
Sbjct: 719 FGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEP 778
Query: 807 VLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTA 866
+L IP+ VL+GIFLYMGV +LS IQ +R+ LL P K+ PD+ ++ V R+HLFT
Sbjct: 779 ILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTG 838
Query: 867 IQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKA-LERVFSPQELLWLD 914
IQ+ CL +LW++KSTPA++ P +L+ V +R+ L +F EL LD
Sbjct: 839 IQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLD 887
>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
Length = 891
Score = 209 bits (532), Expect = 1e-53
Identities = 174/595 (29%), Positives = 272/595 (45%), Gaps = 57/595 (9%)
Query: 331 GPAVPRL----TSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWYPSDFLDALHL 386
GP PR T + HRH + G+ G+ +D+ R+ P YP DF D +
Sbjct: 311 GPVAPRTKERSTVSLPAHRHPEPPKCKDFVPFGK---GIREDIARRFPLYPLDFTDGIIG 367
Query: 387 Q------CFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCLMAGQ 440
+ + L++Y A + I FG L + TDGA V ++ G ++ G + L +GQ
Sbjct: 368 KNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAIDVQKTIAGQSIGGLLYALFSGQ 427
Query: 441 PLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLVRYFT 500
PL IL +T P+ ++ +++ DY LD+ F W G+W + F + S+++ F
Sbjct: 428 PLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLWNSFFLALYAFFNLSLVMSLFK 487
Query: 501 RFTEEGFCALISLIFIYDAVGKMLNLTHTYP----IQKPGSSAYGCLCQYPGPGGNESQW 556
R TEE IS+ F+ DAV + + Y + + L G G + +
Sbjct: 488 RSTEEIIALFISITFVLDAVKGTVKIFWKYYYGHYLDDYHTKRTSSLVSLSGLGASLNAS 547
Query: 557 IRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSLLLFLTSFF 616
+ T +NAS L P H+ A SLL+ L + +
Sbjct: 548 LHTA--------------LNASFLASPT-------ELPSATHSGQATAVLSLLIMLGTLW 586
Query: 617 FAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPREFKPTLPG 676
L K S + VR+ LSD + +A+L AF +++ RE + +
Sbjct: 587 LGYTLYQFKKSPYLHPCVREILSDCALPIAVL------AFSLISSHGF---REIEMSKFR 637
Query: 677 RGWLVSPFG-ANPWWWSVAAALPAL----LLSILIFMDQQITAVILNRMEYRLQKGAGFH 731
SPF A S+ A A+ LLS+L F++Q + A ++N E RL KG +H
Sbjct: 638 YNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLVAALVNAPENRLVKGTAYH 697
Query: 732 LDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGE-RPNFLGIREQRLT 790
DL +A++ S GLPW +A S H+ +L G + ++E RLT
Sbjct: 698 WDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERVENGHIYDTIVNVKETRLT 757
Query: 791 GLVVFILTGASIFLAPV-LKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPD 849
L +L G S+ L PV L++IP PVLYG+FLY+ + +L Q RV LLL P
Sbjct: 758 SLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGNQLVQRVALLLKEQTAYPP 817
Query: 850 LLLLRHVPLTRVHLFTAIQLACLGLL--WIIKSTP-AAIIFPLMLLGLVGVRKAL 901
+R VP ++H FT +Q+ L LL + + S P +IFPL+++ ++ +R L
Sbjct: 818 THYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFPLIMIAMIPIRYIL 872
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 33.5 bits (75), Expect = 0.98
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 16 APRNIPSGELDSNPDPGTGPSPDGPSDTESKELGVPK 52
APR +P + G GPSP+G S TES PK
Sbjct: 1628 APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664
>gi|47078278 choline kinase alpha isoform b [Homo sapiens]
Length = 439
Score = 33.1 bits (74), Expect = 1.3
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Query: 3 MKLPGQEGFEASSAPRNI--PSGELDSNPDPGTGPSPDGPSDTESKELGVPKDPL 55
MK G EA +P + G + P PG G D SD ESK+LG + PL
Sbjct: 1 MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPL 55
>gi|47078276 choline kinase alpha isoform a [Homo sapiens]
Length = 457
Score = 33.1 bits (74), Expect = 1.3
Identities = 21/55 (38%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Query: 3 MKLPGQEGFEASSAPRNI--PSGELDSNPDPGTGPSPDGPSDTESKELGVPKDPL 55
MK G EA +P + G + P PG G D SD ESK+LG + PL
Sbjct: 1 MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPL 55
>gi|30039700 monoacylglycerol O-acyltransferase 3 [Homo sapiens]
Length = 341
Score = 32.7 bits (73), Expect = 1.7
Identities = 18/51 (35%), Positives = 22/51 (43%)
Query: 547 PGPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGC 597
P GG S+WIR R R + L+ + LPP G HP G C
Sbjct: 70 PNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMC 120
>gi|24307991 p53-associated parkin-like cytoplasmic protein [Homo
sapiens]
Length = 2517
Score = 32.3 bits (72), Expect = 2.2
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 888 PLMLLGLVGVRKALERVFSPQELLWLDELMPEEERSIPEKGLEPEHSFSGSDSEDSELMY 947
P ++L + + L+R F +L LD+L E+E EK LE E + + EL
Sbjct: 1630 PQLMLQSLSTSEELQRQFHLFQLQRLDKLFLEQEDE-EEKRLEEEEEEEEEEEAEKELFI 1688
Query: 948 QPKAPEINISV 958
+ +P I+I V
Sbjct: 1689 EDPSPAISILV 1699
>gi|20373171 vang-like 1 [Homo sapiens]
Length = 524
Score = 32.0 bits (71), Expect = 2.8
Identities = 28/124 (22%), Positives = 50/124 (40%)
Query: 751 WYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKF 810
W + T I+ S+ +E A + + +G+ +R GL V G +FL P+
Sbjct: 72 WGETTTAITGTSEHSISQEDIARISKDMEDSVGLDCKRYLGLTVASFLGLLVFLTPIAFI 131
Query: 811 IPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLA 870
+ P+L+ L + + KLL++ R + RV +F A+ L
Sbjct: 132 LLPPILWRDELEPCGTICEGLFISMAFKLLILLIGTWALFFRKRRADMPRVFVFRALLLV 191
Query: 871 CLGL 874
+ L
Sbjct: 192 LIFL 195
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 32.0 bits (71), Expect = 2.8
Identities = 17/43 (39%), Positives = 25/43 (58%), Gaps = 2/43 (4%)
Query: 913 LDELMPEEERSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEIN 955
LD+L E + +KG E EH S DS D E +P+AP+++
Sbjct: 410 LDKL--ENSAAPKKKGFEEEHKDSDDDSSDDEQEKKPEAPKLS 450
>gi|221139764 PHD and ring finger domains 1 [Homo sapiens]
Length = 1648
Score = 31.6 bits (70), Expect = 3.7
Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 4/49 (8%)
Query: 7 GQEGFEASSAPRNIPSGELDSNPD----PGTGPSPDGPSDTESKELGVP 51
G+EGF+ PR +PSG P TG S G S T ++ G P
Sbjct: 550 GEEGFKGCLQPRALPSGSPAQGPSGNRPQSTGLSCQGRSRTPARTAGAP 598
>gi|74271903 chondroitin sulfate synthase 3 [Homo sapiens]
Length = 882
Score = 31.6 bits (70), Expect = 3.7
Identities = 14/52 (26%), Positives = 24/52 (46%)
Query: 309 IPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGR 360
+P P+ P Q + P +++++GP +P R P P LQ+ R
Sbjct: 63 LPQPQSRPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPWQQPPPLQQRRR 114
>gi|21687212 UV radiation resistance associated [Homo sapiens]
Length = 699
Score = 31.2 bits (69), Expect = 4.9
Identities = 15/32 (46%), Positives = 18/32 (56%), Gaps = 3/32 (9%)
Query: 299 PPGRWDPTARIPPPKCLPSQHKRLPSQQREIR 330
PPG P A +PP + H LPSQQR +R
Sbjct: 15 PPG---PAAALPPGSAARALHVELPSQQRRLR 43
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 31.2 bits (69), Expect = 4.9
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 11 FEASSAPRNIPSGELDSNPDPGTGPSPDGPSDTESKELG 49
F + AP +P E + PGT P P P DT S ELG
Sbjct: 428 FRRAPAPPPLPPAEPLAKEKPGTPPGPP-PPDTNSMELG 465
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 31.2 bits (69), Expect = 4.9
Identities = 35/124 (28%), Positives = 52/124 (41%), Gaps = 20/124 (16%)
Query: 97 VPTLALPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVESLSPELRGQLQALLLQRPQ 156
+PT L ++Q L + A G ++ P Q+L + L QLQ L LQ Q
Sbjct: 141 LPTANLTNIQGLVAAAAAGGIMT-LPLQNL-----------QATSSLNSQLQQLQLQLQQ 188
Query: 157 HYNQTTGTRPCWGSTHPRKASDNEEAPLREQCQNPLR----QKLPPGAEAGTVLAGELGF 212
Q P + HP+ A +AP + Q Q PL+ Q+ PP ++ +L
Sbjct: 189 QQQQQQQQPPPSTNQHPQPA---PQAPSQSQ-QQPLQPTPPQQPPPASQQPPAPTSQLQQ 244
Query: 213 LAQP 216
QP
Sbjct: 245 APQP 248
>gi|4885455 SH2B adaptor protein 3 [Homo sapiens]
Length = 575
Score = 30.8 bits (68), Expect = 6.3
Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 21 PSGELDSNPDPGTGPSPDG-PSDTESKELGVPKDP 54
P + +++P+PG GP+ G P S+EL P+ P
Sbjct: 96 PPAKAEASPEPGPGPAAPGLPKARSSEELAPPRPP 130
>gi|239747093 PREDICTED: hypothetical protein XP_002344492 [Homo
sapiens]
Length = 272
Score = 30.8 bits (68), Expect = 6.3
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 18/58 (31%)
Query: 731 HLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESR---------ACAPGERP 779
HLDLFCV+ +L S +++S D RRESR PGERP
Sbjct: 26 HLDLFCVSATPVLLSGFHFQYFLS---------DGSRRESRRKRSWNTECPSFPGERP 74
>gi|88853066 sperm associated antigen 8 isoform 1 [Homo sapiens]
Length = 485
Score = 30.8 bits (68), Expect = 6.3
Identities = 25/97 (25%), Positives = 37/97 (38%), Gaps = 4/97 (4%)
Query: 5 LPGQ-EGFEASSAPRNIPSGELDSNPDPGTGPSPDGPSDTESKELGVPK-DPLLFIQLNE 62
+PG G S P + P S+P P +GP PD D+E P L+ ++
Sbjct: 168 VPGSGSGPGPGSGPGSGPGHGSGSHPGPASGPGPDTGPDSELSPCIPPGFRNLVADRVPN 227
Query: 63 LLGWPQALEW--RETGRWVLFEEKLEVAAGRWSAPHV 97
W Q W ++ W + A G W P +
Sbjct: 228 YTSWSQHCPWEPQKQPPWEFLQVLEPGARGLWKPPDI 264
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,939,213
Number of Sequences: 37866
Number of extensions: 2105611
Number of successful extensions: 6693
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 6602
Number of HSP's gapped (non-prelim): 62
length of query: 959
length of database: 18,247,518
effective HSP length: 112
effective length of query: 847
effective length of database: 14,006,526
effective search space: 11863527522
effective search space used: 11863527522
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.