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Search of human proteins with 150456471
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|150456471 doublecortin domain containing 2B [Homo sapiens]
(349 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|150456471 doublecortin domain containing 2B [Homo sapiens] 714 0.0
gi|117938307 doublecortin domain containing 2 [Homo sapiens] 196 3e-50
gi|239753110 PREDICTED: doublecortin domain-containing protein E... 154 1e-37
gi|239747673 PREDICTED: doublecortin domain-containing protein E... 151 1e-36
gi|239741542 PREDICTED: doublecortin domain-containing protein E... 151 1e-36
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 79 8e-15
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 79 8e-15
gi|4758128 doublecortin-like kinase 1 [Homo sapiens] 70 3e-12
gi|30181244 doublecortin isoform c [Homo sapiens] 70 4e-12
gi|30181240 doublecortin isoform c [Homo sapiens] 70 4e-12
gi|30181246 doublecortin isoform a [Homo sapiens] 70 4e-12
gi|30181242 doublecortin isoform b [Homo sapiens] 69 8e-12
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens] 65 9e-11
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 48 1e-05
gi|7657665 zinc finger and BTB domain containing 32 [Homo sapiens] 41 0.002
gi|66932943 variable charge, X chromosome [Homo sapiens] 40 0.004
gi|48762947 variable charge, X-linked 3A [Homo sapiens] 39 0.005
gi|149999615 variable charge, X-linked 3B [Homo sapiens] 39 0.005
gi|239756837 PREDICTED: similar to pleckstrin homology domain co... 37 0.034
gi|40538728 pleckstrin homology domain containing, family M (wit... 35 0.100
gi|13994322 TBC1 domain family, member 10A [Homo sapiens] 35 0.100
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 33 0.29
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 33 0.29
gi|9945318 MAX binding protein [Homo sapiens] 33 0.38
gi|120587019 zinc finger protein 318 [Homo sapiens] 33 0.38
gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo ... 33 0.50
gi|239755742 PREDICTED: similar to DEAD/H (Asp-Glu-Ala-Asp/His) ... 32 0.65
gi|130979214 adrenocortical dysplasia homolog isoform 3 [Homo sa... 32 0.65
gi|130978956 adrenocortical dysplasia homolog isoform 1 [Homo sa... 32 0.65
gi|130978962 adrenocortical dysplasia homolog isoform 2 [Homo sa... 32 0.65
>gi|150456471 doublecortin domain containing 2B [Homo sapiens]
Length = 349
Score = 714 bits (1842), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MAGGSPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPC 60
MAGGSPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPC
Sbjct: 1 MAGGSPAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPC 60
Query: 61 HGHPVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIG 120
HGHPVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIG
Sbjct: 61 HGHPVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIG 120
Query: 121 RQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTL 180
RQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTL
Sbjct: 121 RQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTL 180
Query: 181 EGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQ 240
EGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQ
Sbjct: 181 EGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQ 240
Query: 241 GHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPSGVIGVYGAPHRRKETAG 300
GHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPSGVIGVYGAPHRRKETAG
Sbjct: 241 GHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPSGVIGVYGAPHRRKETAG 300
Query: 301 ALEVADDEDTQTEEPLDQRAAQIVEEALSLENQPGAGAAISASAPALPS 349
ALEVADDEDTQTEEPLDQRAAQIVEEALSLENQPGAGAAISASAPALPS
Sbjct: 301 ALEVADDEDTQTEEPLDQRAAQIVEEALSLENQPGAGAAISASAPALPS 349
>gi|117938307 doublecortin domain containing 2 [Homo sapiens]
Length = 476
Score = 196 bits (497), Expect = 3e-50
Identities = 125/338 (36%), Positives = 182/338 (53%), Gaps = 19/338 (5%)
Query: 6 PAAKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPL-AVRALYTPCHGHP 64
P K V+VYRNGDPF+ G ++V+ +++ + E FL EVT VQAP AVR +YTP GH
Sbjct: 14 PVVKSVLVYRNGDPFYAGRRVVIHEKKVSSFEVFLKEVTGGVQAPFGAVRNIYTPRTGHR 73
Query: 65 VTNLADLKNRGQYVAAGFERFHKLHYLP-HRGKDPGGKSCRLQGPPVTRHLCDGAIGRQL 123
+ L +++ G YVA G E F KL+YL K + + PV + + +
Sbjct: 74 IRKLDQIQSGGNYVAGGQEAFKKLNYLDIGEIKKRPMEVVNTEVKPVIHSRINVSARFRK 133
Query: 124 PAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGL 183
P P I + NGDL++P L + + W+ VL+++TEK+ L+SGAV +L TLEG
Sbjct: 134 PLQEPCTIFLIANGDLINPASRLLIPRKTLNQWDHVLQMVTEKITLRSGAVHRLYTLEGK 193
Query: 184 PLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQ-----PP--GSKSRPHR 236
+ +G EL G +YVAVG D+FK LPY ELL ++ R Q PP GS+
Sbjct: 194 LVESGAELENGQFYVAVGRDKFKKLPYSELLFDKSTMRRPFGQKASSLPPIVGSRKSKGS 253
Query: 237 QGAQGHRAQVTQPSPKEPDRIK--------PSAFYARPQQTIQPRSKLPTLSFPSGVIGV 288
+ ++ V P +K S + +Q ++ ++ T+ P+ G+
Sbjct: 254 GNDRHSKSTVGSSDNSSPQPLKRKGKKEDVNSEKLTKLKQNVKLKNSQETI--PNSDEGI 311
Query: 289 YGAPHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEE 326
+ A R ET GA EV +DEDTQ E P+DQR A+IV+E
Sbjct: 312 FKAGAERSETRGAAEVQEDEDTQVEVPVDQRPAEIVDE 349
>gi|239753110 PREDICTED: doublecortin domain-containing protein
ENSP00000382097-like [Homo sapiens]
Length = 530
Score = 154 bits (389), Expect = 1e-37
Identities = 126/350 (36%), Positives = 166/350 (47%), Gaps = 53/350 (15%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTN 67
AK +VVYRNGDPF+ G + V+++RR T EA L ++T V P VR L+TP GH V
Sbjct: 85 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 144
Query: 68 LADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGR--QLPA 125
L L+ G+YVAAG ERF +L Y+ + P + PV CD + Q
Sbjct: 145 LDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVH--CDINVPSKWQTYH 202
Query: 126 GAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGLPL 185
+I+VF NG L PP + + + + DW+ VL + EKV G V KL T+ G L
Sbjct: 203 RISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLL 261
Query: 186 SAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKS---------RPHR 236
K+L H+YVAVG + FK PY + SP +P G KS P R
Sbjct: 262 GDSKDLQDNHFYVAVGLETFKYFPYWK----SPRVPSEVQHVSGVKSYLFHSLTEHSPRR 317
Query: 237 QGAQ-----GHRAQVTQ------------PSPKEP---DRIKP----SAFYARPQQTIQP 272
Q R + TQ KEP D I P S +YA+ +
Sbjct: 318 QAPSPFYRTSERPETTQLTWRARDPVLVDSKGKEPCKYDGIPPKTQDSVYYAKEE----- 372
Query: 273 RSKLPTLSFP---SGVIG-VYGAPHRRKETAGALEVADDEDTQTEEPLDQ 318
K TL+ P G G VY AP KET GAL+V ++ + Q E P+DQ
Sbjct: 373 --KKKTLAEPLVQRGAEGDVYKAPTPSKETQGALDVKEEHNVQLEVPVDQ 420
>gi|239747673 PREDICTED: doublecortin domain-containing protein
ENSP00000382097-like [Homo sapiens]
Length = 714
Score = 151 bits (381), Expect = 1e-36
Identities = 113/319 (35%), Positives = 156/319 (48%), Gaps = 44/319 (13%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTN 67
AK +VVYRNGDPF+ G + V+++RR T EA L ++T V P VR L+TP GH V
Sbjct: 191 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 250
Query: 68 LADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGR--QLPA 125
L L+ G+YVAAG ERF +L Y+ + P + PV CD + Q
Sbjct: 251 LDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVH--CDINVPSKWQTYH 308
Query: 126 GAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGLPL 185
+I+VF NG L PP + + + + DW+ VL + EKV G V KL T+ G L
Sbjct: 309 RISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLL 367
Query: 186 SAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQ 245
K+L H+YVAVG + FK PY W+ P S+
Sbjct: 368 GDSKDLQDNHFYVAVGLETFKYFPY--------------WKSPRVDSKG----------- 402
Query: 246 VTQPSPKE--PDRIKPSAFYARPQQTIQPRSKLPTLSFP---SGVIG-VYGAPHRRKETA 299
+P + P + + S +YA+ + K TL+ P G G VY AP KET
Sbjct: 403 -KEPCKYDGIPPKTQDSVYYAKEE-------KKKTLAEPLVQRGAEGDVYKAPTPSKETQ 454
Query: 300 GALEVADDEDTQTEEPLDQ 318
GAL+V ++ + Q E P+DQ
Sbjct: 455 GALDVKEEHNVQLEVPVDQ 473
>gi|239741542 PREDICTED: doublecortin domain-containing protein
ENSP00000382097-like [Homo sapiens]
Length = 510
Score = 151 bits (381), Expect = 1e-36
Identities = 113/319 (35%), Positives = 156/319 (48%), Gaps = 44/319 (13%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTN 67
AK +VVYRNGDPF+ G + V+++RR T EA L ++T V P VR L+TP GH V
Sbjct: 191 AKTIVVYRNGDPFYVGKKFVLSRRRAATFEALLEQLTEQVDVPFGVRRLFTPTRGHRVLG 250
Query: 68 LADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGR--QLPA 125
L L+ G+YVAAG ERF +L Y+ + P + PV CD + Q
Sbjct: 251 LDALQAGGKYVAAGRERFKELDYIHIVPRKPAKIRKLKEIKPVVH--CDINVPSKWQTYH 308
Query: 126 GAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLCTLEGLPL 185
+I+VF NG L PP + + + + DW+ VL + EKV G V KL T+ G L
Sbjct: 309 RISRHINVFTNGRLFIPPAKIIIPKFSLSDWDIVLATIGEKV-FPLGGVRKLFTMNGHLL 367
Query: 186 SAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQ 245
K+L H+YVAVG + FK PY W+ P S+
Sbjct: 368 GDSKDLQDNHFYVAVGLETFKYFPY--------------WKSPRVDSKG----------- 402
Query: 246 VTQPSPKE--PDRIKPSAFYARPQQTIQPRSKLPTLSFP---SGVIG-VYGAPHRRKETA 299
+P + P + + S +YA+ + K TL+ P G G VY AP KET
Sbjct: 403 -KEPCKYDGIPPKTQDSVYYAKEE-------KKKTLAEPLVQRGAEGDVYKAPTPSKETQ 454
Query: 300 GALEVADDEDTQTEEPLDQ 318
GAL+V ++ + Q E P+DQ
Sbjct: 455 GALDVKEEHNVQLEVPVDQ 473
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 78.6 bits (192), Expect = 8e-15
Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 14/209 (6%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSA----VQAPLAVRALYTPCHGH 63
AK+ YRNGD +F G ++ RF + +A L E+T + V P VR +YT
Sbjct: 71 AKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSR 130
Query: 64 PVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKD-----PGGKSCRLQGPPVTRHLCDGA 118
VT+L +L YV A E F K+ Y + + GG S L +
Sbjct: 131 KVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRALAAASSVK----SE 186
Query: 119 IGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLC 178
+ P + V R+G + L++ + +E VL +TE +KL SG V +LC
Sbjct: 187 VKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLC 246
Query: 179 TLEGLPLSAGKELV-TGHYYVAVGEDEFK 206
TL+G ++ ++ ++A G ++F+
Sbjct: 247 TLDGKQVTCLQDFFGDDDVFIACGPEKFR 275
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 78.6 bits (192), Expect = 8e-15
Identities = 59/209 (28%), Positives = 95/209 (45%), Gaps = 14/209 (6%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSA----VQAPLAVRALYTPCHGH 63
AK+ YRNGD +F G ++ RF + +A L E+T + V P VR +YT
Sbjct: 71 AKKARFYRNGDRYFKGLVFAISSDRFRSFDALLIELTRSLSDNVNLPQGVRTIYTIDGSR 130
Query: 64 PVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKD-----PGGKSCRLQGPPVTRHLCDGA 118
VT+L +L YV A E F K+ Y + + GG S L +
Sbjct: 131 KVTSLDELLEGESYVCASNEPFRKVDYTKNINPNWSVNIKGGTSRALAAASSVK----SE 186
Query: 119 IGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLC 178
+ P + V R+G + L++ + +E VL +TE +KL SG V +LC
Sbjct: 187 VKESKDFIKPKLVTVIRSGVKPRKAVRILLNKKTAHSFEQVLTDITEAIKLDSGVVKRLC 246
Query: 179 TLEGLPLSAGKELV-TGHYYVAVGEDEFK 206
TL+G ++ ++ ++A G ++F+
Sbjct: 247 TLDGKQVTCLQDFFGDDDVFIACGPEKFR 275
>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
Length = 729
Score = 70.1 bits (170), Expect = 3e-12
Identities = 56/212 (26%), Positives = 96/212 (45%), Gaps = 16/212 (7%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSA----VQAPLAVRALYTPCHGH 63
AK+V YRNGD +F G ++ RF + EA L ++T V P VR +YT
Sbjct: 56 AKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLK 115
Query: 64 PVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCRLQGPPVTRHLCDGAIGRQL 123
+++L L YV E F KL Y + +P S ++ +R + A +
Sbjct: 116 KISSLDQLVEGESYVCGSIEPFKKLEYT--KNVNPNW-SVNVKTTSASRAVSSLATAKGS 172
Query: 124 PAGA--------PSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVC 175
P+ P + + R+G + L++ + +E VL +T+ +KL SG V
Sbjct: 173 PSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVK 232
Query: 176 KLCTLEGLPLSAGKELV-TGHYYVAVGEDEFK 206
+L TL+G + ++ ++A G ++F+
Sbjct: 233 RLYTLDGKQVMCLQDFFGDDDIFIACGPEKFR 264
>gi|30181244 doublecortin isoform c [Homo sapiens]
Length = 360
Score = 69.7 bits (169), Expect = 4e-12
Identities = 68/294 (23%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSA----VQAPLAVRALYTPCHGH 63
AK+V YRNGD +F G V+ RF + +A L ++T + + P VR +YT
Sbjct: 52 AKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSR 111
Query: 64 PVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGK-----SCRLQGPPVTRHLCDGA 118
+ ++ +L+ YV + F K+ Y + +P S ++ P
Sbjct: 112 KIGSMDELEEGESYVCSSDNFFKKVEYT--KNVNPNWSVNVKTSANMKAPQSLASSNSAQ 169
Query: 119 IGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLC 178
P + + R+G + L++ + +E VL +TE +KL++G V KL
Sbjct: 170 ARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLY 229
Query: 179 TLEGLPLSAGKELV-TGHYYVAVGEDEFK--------DLPYLELLVPSPSLPRGCWQPPG 229
TL+G ++ + ++A G ++F+ D ++ +PS G P
Sbjct: 230 TLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAG----PK 285
Query: 230 SKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPS 283
+ P + A+ SP + SA Q P+SK +S P+
Sbjct: 286 ASPTPQKTSAKSPGPMRRSKSPAD------SANGTSSSQLSTPKSKQSPISTPT 333
>gi|30181240 doublecortin isoform c [Homo sapiens]
Length = 360
Score = 69.7 bits (169), Expect = 4e-12
Identities = 68/294 (23%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSA----VQAPLAVRALYTPCHGH 63
AK+V YRNGD +F G V+ RF + +A L ++T + + P VR +YT
Sbjct: 52 AKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSR 111
Query: 64 PVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGK-----SCRLQGPPVTRHLCDGA 118
+ ++ +L+ YV + F K+ Y + +P S ++ P
Sbjct: 112 KIGSMDELEEGESYVCSSDNFFKKVEYT--KNVNPNWSVNVKTSANMKAPQSLASSNSAQ 169
Query: 119 IGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLC 178
P + + R+G + L++ + +E VL +TE +KL++G V KL
Sbjct: 170 ARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLY 229
Query: 179 TLEGLPLSAGKELV-TGHYYVAVGEDEFK--------DLPYLELLVPSPSLPRGCWQPPG 229
TL+G ++ + ++A G ++F+ D ++ +PS G P
Sbjct: 230 TLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAG----PK 285
Query: 230 SKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPS 283
+ P + A+ SP + SA Q P+SK +S P+
Sbjct: 286 ASPTPQKTSAKSPGPMRRSKSPAD------SANGTSSSQLSTPKSKQSPISTPT 333
>gi|30181246 doublecortin isoform a [Homo sapiens]
Length = 441
Score = 69.7 bits (169), Expect = 4e-12
Identities = 68/294 (23%), Positives = 120/294 (40%), Gaps = 30/294 (10%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSA----VQAPLAVRALYTPCHGH 63
AK+V YRNGD +F G V+ RF + +A L ++T + + P VR +YT
Sbjct: 133 AKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSR 192
Query: 64 PVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGK-----SCRLQGPPVTRHLCDGA 118
+ ++ +L+ YV + F K+ Y + +P S ++ P
Sbjct: 193 KIGSMDELEEGESYVCSSDNFFKKVEYT--KNVNPNWSVNVKTSANMKAPQSLASSNSAQ 250
Query: 119 IGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLC 178
P + + R+G + L++ + +E VL +TE +KL++G V KL
Sbjct: 251 ARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLY 310
Query: 179 TLEGLPLSAGKELV-TGHYYVAVGEDEFK--------DLPYLELLVPSPSLPRGCWQPPG 229
TL+G ++ + ++A G ++F+ D ++ +PS G P
Sbjct: 311 TLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAG----PK 366
Query: 230 SKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPS 283
+ P + A+ SP + SA Q P+SK +S P+
Sbjct: 367 ASPTPQKTSAKSPGPMRRSKSPAD------SANGTSSSQLSTPKSKQSPISTPT 414
>gi|30181242 doublecortin isoform b [Homo sapiens]
Length = 365
Score = 68.6 bits (166), Expect = 8e-12
Identities = 67/294 (22%), Positives = 119/294 (40%), Gaps = 25/294 (8%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSA----VQAPLAVRALYTPCHGH 63
AK+V YRNGD +F G V+ RF + +A L ++T + + P VR +YT
Sbjct: 52 AKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRSLSDNINLPQGVRYIYTIDGSR 111
Query: 64 PVTNLADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGK-----SCRLQGPPVTRHLCDGA 118
+ ++ +L+ YV + F K+ Y + +P S ++ P
Sbjct: 112 KIGSMDELEEGESYVCSSDNFFKKVEYT--KNVNPNWSVNVKTSANMKAPQSLASSNSAQ 169
Query: 119 IGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQSGAVCKLC 178
P + + R+G + L++ + +E VL +TE +KL++G V KL
Sbjct: 170 ARENKDFVRPKLVTIIRSGVKPRKAVRVLLNKKTAHSFEQVLTDITEAIKLETGVVKKLY 229
Query: 179 TLEGLPLSAGKELV-TGHYYVAVGEDEFK--------DLPYLELLVPSPSLPRGCWQPPG 229
TL+G ++ + ++A G ++F+ D ++ +PS G P
Sbjct: 230 TLDGKQVTCLHDFFGDDDVFIACGPEKFRYAQDDFSLDENECRVMKGNPSATAG----PK 285
Query: 230 SKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPS 283
+ P + A+ SP + A Q P+SK +S P+
Sbjct: 286 ASPTPQKTSAKSPGPMRRSKSPADSGN-DQDANGTSSSQLSTPKSKQSPISTPT 338
>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
Length = 2156
Score = 65.1 bits (157), Expect = 9e-11
Identities = 61/207 (29%), Positives = 96/207 (46%), Gaps = 21/207 (10%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTN 67
AKR+ Y++GDP F G ++VV R F + +A L ++ V P VR + TP H +T
Sbjct: 35 AKRISFYKSGDPQFGGVRVVVNPRSFKSFDALLDNLSRKVPLPFGVRNISTPRGRHSITR 94
Query: 68 LADLKNRGQYVAAGFERFHKLHYLPHRGKDPGGKSCR---LQGPPVTRHLCDGAIGRQLP 124
L +L++ Y+ + + + R + S R PP + A G P
Sbjct: 95 LEELEDGESYLCSHGRKVQPVDLDKARRRPRPWLSSRAISAHSPP--HPVAVAAPGMPRP 152
Query: 125 AGAPSYIHVFRNGDLVSPPFSLKLSQAASQDWETVLKLLTE-----KVKLQSGAVCKLCT 179
P + VFRNGD ++ LS+ +Q +E L+ LTE VKL + ++ +
Sbjct: 153 ---PRSLVVFRNGD-PKTRRAVLLSRRVTQSFEAFLQHLTEVMQRPVVKLYATDGRRVPS 208
Query: 180 LEGLPLSAGKELVTGHYYVAVGEDEFK 206
L+ + LS+G VA G + FK
Sbjct: 209 LQAVILSSGA-------VVAAGREPFK 228
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/73 (34%), Positives = 40/73 (54%)
Query: 8 AKRVVVYRNGDPFFPGSQLVVTQRRFPTMEAFLCEVTSAVQAPLAVRALYTPCHGHPVTN 67
AK++ + GDP F G +L V QR F T A + E++ V VR++ TP H ++
Sbjct: 33 AKKITFLKRGDPRFAGVRLAVHQRAFKTFSALMDELSQRVPLSFGVRSVTTPRGLHSLSA 92
Query: 68 LADLKNRGQYVAA 80
L L++ G Y+ +
Sbjct: 93 LEQLEDGGCYLCS 105
>gi|7657665 zinc finger and BTB domain containing 32 [Homo sapiens]
Length = 487
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 12/123 (9%)
Query: 219 SLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPT 278
SL CW+ G +++ G + H Q P++P R P P + +P T
Sbjct: 104 SLEEACWRARGDRAKKPDPGLKKH-----QEEPEKPSR-NPERELGDPGEKQKPEQVSRT 157
Query: 279 LSFPSGVIGVYGAPHRRKETAGALEVADDEDTQTEE-----PLDQRAAQIVEEALS-LEN 332
++ + P R E AGA + A E T+++E P+ QR A L+ L
Sbjct: 158 GGREQEMLHKHSPPRGRPEMAGATQEAQQEQTRSKEKRLQAPVGQRGADGKHGVLTWLRE 217
Query: 333 QPG 335
PG
Sbjct: 218 NPG 220
>gi|66932943 variable charge, X chromosome [Homo sapiens]
Length = 206
Score = 39.7 bits (91), Expect = 0.004
Identities = 32/118 (27%), Positives = 50/118 (42%), Gaps = 4/118 (3%)
Query: 216 PSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSK 275
PSPS P+ K + R+G +G + T+ + + + A P + QP +
Sbjct: 26 PSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESAP--AAPGPSDQPSQE 83
Query: 276 LPTLSFPSGVIGVYGAPHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEEALSLENQ 333
LP P G H LE ++++ EEPL Q + VEE LS E++
Sbjct: 84 LPQHELPPEEPVSEGTQHDPLSQEAELEEPLSQESEVEEPLSQESQ--VEEPLSQESE 139
>gi|48762947 variable charge, X-linked 3A [Homo sapiens]
Length = 186
Score = 39.3 bits (90), Expect = 0.005
Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 4/118 (3%)
Query: 216 PSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSK 275
PSPS P+ K + R+G +G + T+ + + A P + QP +
Sbjct: 26 PSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESGP--AAPGPSDQPSQE 83
Query: 276 LPTLSFPSGVIGVYGAPHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEEALSLENQ 333
LP P G H LE ++++ EEPL Q + VEE LS E++
Sbjct: 84 LPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEVEEPLSQESQ--VEEPLSQESE 139
>gi|149999615 variable charge, X-linked 3B [Homo sapiens]
Length = 216
Score = 39.3 bits (90), Expect = 0.005
Identities = 32/118 (27%), Positives = 49/118 (41%), Gaps = 4/118 (3%)
Query: 216 PSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSK 275
PSPS P+ K + R+G +G + T+ + + A P + QP +
Sbjct: 26 PSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESGP--AAPGPSDQPSQE 83
Query: 276 LPTLSFPSGVIGVYGAPHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEEALSLENQ 333
LP P G H LE ++++ EEPL Q + VEE LS E++
Sbjct: 84 LPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEVEEPLSQESQ--VEEPLSQESE 139
>gi|239756837 PREDICTED: similar to pleckstrin homology domain
containing, family M (with RUN domain) member 1, partial
[Homo sapiens]
Length = 623
Score = 36.6 bits (83), Expect = 0.034
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 202 EDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSA 261
EDE+ ++ Y + P P+GC P S P QG ++ + EPD IK S
Sbjct: 198 EDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEP--AALQGTQSDWSSAQVPEPDAIKESL 255
Query: 262 FYARPQQTIQP 272
Y +T P
Sbjct: 256 LYLYMDRTWMP 266
>gi|40538728 pleckstrin homology domain containing, family M (with
RUN domain) member 1 [Homo sapiens]
Length = 1056
Score = 35.0 bits (79), Expect = 0.100
Identities = 22/71 (30%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 202 EDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSA 261
EDE+ ++ Y + P P+GC P S P QG + + EPD IK S
Sbjct: 632 EDEWVNVQYPDQPEEPPEAPQGCLSPSDLLSEP--AALQGTQFDWSSAQVPEPDAIKESL 689
Query: 262 FYARPQQTIQP 272
Y +T P
Sbjct: 690 LYLYMDRTWMP 700
>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
Length = 508
Score = 35.0 bits (79), Expect = 0.100
Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 11/103 (10%)
Query: 214 LVPSPSLPRGCWQP-PGSKSRP---------HRQGAQGHRAQVTQPSPKEPDRIKPSAFY 263
L PSPS+ P PGSK++P R+ +G R Q+ +P + +A
Sbjct: 404 LQPSPSIRLPLDAPLPGSKAKPKPPKQAQKEQRKQMKG-RGQLEKPPAPNQAMVVAAAGD 462
Query: 264 ARPQQTIQPRSKLPTLSFPSGVIGVYGAPHRRKETAGALEVAD 306
A P Q + P+ P S P + A HR +E+ + E D
Sbjct: 463 ACPPQHVPPKDSAPKDSAPQDLAPQVSAHHRSQESLTSQESED 505
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 33.5 bits (75), Expect = 0.29
Identities = 33/123 (26%), Positives = 42/123 (34%), Gaps = 18/123 (14%)
Query: 224 CWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPS 283
C Q G+K + RA PS P P QT+ K P +SF
Sbjct: 950 CSQAAGTKGAEETSWSGEERAAKV-PSTPPPKAAPPPPALTPDSQTVDSSCKTPEVSF-- 1006
Query: 284 GVIGVYGAPHRRKETAGALEVADDEDTQTEEPLDQRAAQIVEEALSLENQPGAGAAISAS 343
P E AG A++E+ + EE EE E QP A S +
Sbjct: 1007 -------LPEEATEEAGVRGGAEEEEEEEEEE--------EEEEEEEEQQPATTTATSTA 1051
Query: 344 APA 346
A A
Sbjct: 1052 AAA 1054
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 33.5 bits (75), Expect = 0.29
Identities = 43/151 (28%), Positives = 56/151 (37%), Gaps = 24/151 (15%)
Query: 92 PHRGKDPGGKSCRLQGPPVTRHLCDGAIGRQLPAGAPSYIHVFRNGDLVSPPFSLKLSQA 151
P G+D K L PP+ R R P G + + +
Sbjct: 2469 PEHGEDTIAKVKGLVKPPLKR-------SRSAPDGGDEENQEQLQDQIAE---GSSIEEE 2518
Query: 152 ASQDWETVLKLLTEKVKLQSGAVCK----LCTLEGLPLSAGKELVTGHYYVAVG-----E 202
D T+L+LL E K+Q C L T EGL L GKE H+YV G
Sbjct: 2519 EKTDNATLLRLLEEGEKIQHMYRCARVQGLDTSEGL-LLFGKE----HFYVIDGFTMTAT 2573
Query: 203 DEFKDLPYLELLVPSPSLPRGCWQPPGSKSR 233
E +D+ L + P +PRG Q P R
Sbjct: 2574 REIRDIETLPPNMHEPIIPRGARQGPSQLKR 2604
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 33.1 bits (74), Expect = 0.38
Identities = 30/113 (26%), Positives = 44/113 (38%), Gaps = 14/113 (12%)
Query: 214 LVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPR 273
L P P LP P + +P GA G + P P P P+ + TI P
Sbjct: 101 LPPPPPLPAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPN 160
Query: 274 -SKLPTLSFPSGVIGVYGAPHRRKE-----------TAGALEVADDEDTQTEE 314
S P P+ V+ + APH + T G L++A E+ ++ E
Sbjct: 161 GSPKPLQPLPTPVLTI--APHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSE 211
>gi|120587019 zinc finger protein 318 [Homo sapiens]
Length = 2279
Score = 33.1 bits (74), Expect = 0.38
Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 6/68 (8%)
Query: 227 PPGSKSR-PHRQ--GAQGHRAQVTQPSPKEPDRIKPSAFYARPQQTIQPRSKLPTLSFPS 283
P GS SR P R+ GHR + PSP R+ PS AR PR + FP
Sbjct: 45 PSGSSSRTPARRPRSPSGHRGRRASPSPPRGRRVSPSPPRARRGSPSPPRGR---RLFPP 101
Query: 284 GVIGVYGA 291
G G G+
Sbjct: 102 GPAGFRGS 109
>gi|239751418 PREDICTED: hypothetical protein XP_002347841 [Homo
sapiens]
Length = 528
Score = 32.7 bits (73), Expect = 0.50
Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)
Query: 202 EDEFKDLPYLELLVPSPSLPRGCWQPPGSKSRPHRQGAQGHRAQVTQPSPKEPDRIKPSA 261
EDE+ ++ Y + P P+GC P S P QG ++ + E D IK S
Sbjct: 115 EDEWVNVQYSDQPEEPPEAPQGCLSPSDLLSEP--AALQGTQSDWSSAQVPELDAIKESL 172
Query: 262 FYARPQQTIQP 272
Y +T P
Sbjct: 173 LYLYMDRTWMP 183
>gi|239755742 PREDICTED: similar to DEAD/H (Asp-Glu-Ala-Asp/His) box
polypeptide 11 (CHL1-like helicase homolog, S.
cerevisiae) [Homo sapiens]
Length = 282
Score = 32.3 bits (72), Expect = 0.65
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 7/63 (11%)
Query: 115 CDGAIGRQLPAGAPSYIHVF----RNGDLVSPPFSLKLSQAASQDWETVLKLLTEKVKLQ 170
C+GA G PAG P+++ F DLV+ LK+ QA + E L+ L +V+L+
Sbjct: 92 CEGAAGTPRPAGEPAWVTQFVQKKEERDLVN---RLKVEQARRKQREERLQQLQHRVQLK 148
Query: 171 SGA 173
A
Sbjct: 149 YAA 151
>gi|130979214 adrenocortical dysplasia homolog isoform 3 [Homo
sapiens]
Length = 528
Score = 32.3 bits (72), Expect = 0.65
Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 2/115 (1%)
Query: 169 LQSGAVCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPP 228
LQ ++ + + P S+G + GH LP L L P P P
Sbjct: 341 LQDLSLTLIASPPSSPSSSGTPALPGHMSSEESGTSISLLPALSLAAPDPGQRSSSQPSP 400
Query: 229 GSKSRPHRQGAQGHRAQVTQPSPKE--PDRIKPSAFYARPQQTIQPRSKLPTLSF 281
S P + A T SP + + P + P Q + R + P+L F
Sbjct: 401 AICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQALVTRPQKPSLEF 455
>gi|130978956 adrenocortical dysplasia homolog isoform 1 [Homo
sapiens]
Length = 544
Score = 32.3 bits (72), Expect = 0.65
Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 2/115 (1%)
Query: 169 LQSGAVCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPP 228
LQ ++ + + P S+G + GH LP L L P P P
Sbjct: 344 LQDLSLTLIASPPSSPSSSGTPALPGHMSSEESGTSISLLPALSLAAPDPGQRSSSQPSP 403
Query: 229 GSKSRPHRQGAQGHRAQVTQPSPKE--PDRIKPSAFYARPQQTIQPRSKLPTLSF 281
S P + A T SP + + P + P Q + R + P+L F
Sbjct: 404 AICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQALVTRPQKPSLEF 458
>gi|130978962 adrenocortical dysplasia homolog isoform 2 [Homo
sapiens]
Length = 541
Score = 32.3 bits (72), Expect = 0.65
Identities = 27/115 (23%), Positives = 40/115 (34%), Gaps = 2/115 (1%)
Query: 169 LQSGAVCKLCTLEGLPLSAGKELVTGHYYVAVGEDEFKDLPYLELLVPSPSLPRGCWQPP 228
LQ ++ + + P S+G + GH LP L L P P P
Sbjct: 341 LQDLSLTLIASPPSSPSSSGTPALPGHMSSEESGTSISLLPALSLAAPDPGQRSSSQPSP 400
Query: 229 GSKSRPHRQGAQGHRAQVTQPSPKE--PDRIKPSAFYARPQQTIQPRSKLPTLSF 281
S P + A T SP + + P + P Q + R + P+L F
Sbjct: 401 AICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQALVTRPQKPSLEF 455
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,431,244
Number of Sequences: 37866
Number of extensions: 909384
Number of successful extensions: 3745
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 3470
Number of HSP's gapped (non-prelim): 321
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.