Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 150378449

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|150378449 X-ray radiation resistance associated 1 [Homo
sapiens]
         (792 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|150378449 X-ray radiation resistance associated 1 [Homo sapiens]  1595   0.0  
gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso...    52   2e-06
gi|40217803 leucine rich repeat containing 8 family, member E [H...    49   2e-05
gi|61742786 leucine rich repeat and death domain containing prot...    49   2e-05
gi|61742784 leucine rich repeat and death domain containing prot...    49   2e-05
gi|6912638 ras suppressor protein 1 isoform 1 [Homo sapiens]           48   3e-05
gi|110349719 titin isoform N2-A [Homo sapiens]                         48   4e-05
gi|20143971 toll-like receptor 6 [Homo sapiens]                        47   9e-05
gi|157694513 leucine-rich repeat-containing G protein-coupled re...    47   9e-05
gi|16751843 toll-like receptor 5 [Homo sapiens]                        46   2e-04
gi|34577083 ras suppressor protein 1 isoform 2 [Homo sapiens]          46   2e-04
gi|33285015 leucine rich repeat containing 28 [Homo sapiens]           45   2e-04
gi|4504379 leucine-rich repeat-containing G protein-coupled rece...    45   3e-04
gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa...    45   3e-04
gi|40217825 slit and trk like 6 [Homo sapiens]                         45   3e-04
gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens]    45   3e-04
gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens]     45   3e-04
gi|110825984 malignant fibrous histiocytoma amplified sequence 1...    44   4e-04
gi|7662320 leucine-rich repeats and immunoglobulin-like domains ...    44   4e-04
gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]              44   6e-04
gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]              44   6e-04
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre...    44   8e-04
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec...    44   8e-04
gi|62241040 leucine rich repeat containing 8 family, member A [H...    43   0.001
gi|187829877 leucine rich repeat containing 8 family, member A [...    43   0.001
gi|187829871 leucine rich repeat containing 8 family, member A [...    43   0.001
gi|61966761 leucine rich repeat containing 26 [Homo sapiens]           43   0.001
gi|45827729 scribble isoform b [Homo sapiens]                          43   0.001
gi|45827731 scribble isoform a [Homo sapiens]                          43   0.001
gi|194394161 leucine rich repeat containing 57 [Homo sapiens]          43   0.001

>gi|150378449 X-ray radiation resistance associated 1 [Homo sapiens]
          Length = 792

 Score = 1595 bits (4129), Expect = 0.0
 Identities = 792/792 (100%), Positives = 792/792 (100%)

Query: 1   MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRE 60
           MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRE
Sbjct: 1   MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRE 60

Query: 61  SLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTINAKENDFKHFHS 120
           SLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTINAKENDFKHFHS
Sbjct: 61  SLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTINAKENDFKHFHS 120

Query: 121 VIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAI 180
           VIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAI
Sbjct: 121 VIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAI 180

Query: 181 CDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRL 240
           CDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRL
Sbjct: 181 CDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRL 240

Query: 241 SNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQS 300
           SNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQS
Sbjct: 241 SNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQS 300

Query: 301 KPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLK 360
           KPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLK
Sbjct: 301 KPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLK 360

Query: 361 ARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLK 420
           ARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLK
Sbjct: 361 ARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLK 420

Query: 421 SFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSK 480
           SFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSK
Sbjct: 421 SFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSK 480

Query: 481 DMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSH 540
           DMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSH
Sbjct: 481 DMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSH 540

Query: 541 LSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVK 600
           LSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVK
Sbjct: 541 LSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVK 600

Query: 601 GTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKL 660
           GTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKL
Sbjct: 601 GTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKL 660

Query: 661 DTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRL 720
           DTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRL
Sbjct: 661 DTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRL 720

Query: 721 VNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACPALSESQPKFGHFLEFMDE 780
           VNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACPALSESQPKFGHFLEFMDE
Sbjct: 721 VNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACPALSESQPKFGHFLEFMDE 780

Query: 781 FCQEPTASDSQG 792
           FCQEPTASDSQG
Sbjct: 781 FCQEPTASDSQG 792


>gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor
           [Homo sapiens]
          Length = 639

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 46/140 (32%), Positives = 61/140 (43%), Gaps = 18/140 (12%)

Query: 130 LLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHL 189
           L  L+   T P L  LDL+ N ++++ +       L  LD+SFN LT   +  L  L  L
Sbjct: 83  LTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGEL 142

Query: 190 RVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASL 249
           + L L GN L +LPP L                 +   P LE L L +N L+       L
Sbjct: 143 QELYLKGNELKTLPPGL-----------------LTPTPKLEKLSLANNNLTELPA-GLL 184

Query: 250 AGLRRLKKLSLDENRIIRIP 269
            GL  L  L L EN +  IP
Sbjct: 185 NGLENLDTLLLQENSLYTIP 204


>gi|40217803 leucine rich repeat containing 8 family, member E [Homo
           sapiens]
          Length = 796

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 49/180 (27%), Positives = 77/180 (42%), Gaps = 24/180 (13%)

Query: 97  HCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIY 156
           H V     L  ++ K+N  +    ++       L+ L  +H            N I  + 
Sbjct: 599 HAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWH------------NQIAYVP 646

Query: 157 VKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLA-------VA 209
                 + LE L LS+N L       LG+   LR+L ++ NGL SLPP +        +A
Sbjct: 647 EHVRKLRSLEQLYLSYNKLETLP-SQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 705

Query: 210 EQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269
               ++ +L  + +  R   L TL+L DN+LS  S    +  LR L +L L  NR+  +P
Sbjct: 706 LSYNALEALPEELFFCR--KLRTLLLGDNQLSQLS--PHVGALRALSRLELKGNRLEALP 761


>gi|61742786 leucine rich repeat and death domain containing protein
           isoform 3 [Homo sapiens]
          Length = 893

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/139 (35%), Positives = 65/139 (46%), Gaps = 20/139 (14%)

Query: 142 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTS 201
           L  LDL+FN ++T+       + L  L LS N L+ E    LG LP L  L +T N L +
Sbjct: 127 LAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLS-ELPEALGALPALTFLTVTHNRLQT 185

Query: 202 LPPNLAVAEQEASVTSLTSKRYILRFPALETL---------MLDDNRLSN--PSCFASLA 250
           LPP L            T +R  L    L+TL         +L+ N  SN   S  ASLA
Sbjct: 186 LPPALGALS--------TLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLA 237

Query: 251 GLRRLKKLSLDENRIIRIP 269
           GLR L+ L L  N +  +P
Sbjct: 238 GLRSLRLLVLHSNLLASVP 256



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 43/136 (31%), Positives = 59/136 (43%), Gaps = 21/136 (15%)

Query: 134 EAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLL 193
           EA    PAL  L +  N ++T+    G    L+ LDLS N L      ++G L  L  L 
Sbjct: 165 EALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDT-LPPEIGGLGSLLELN 223

Query: 194 LTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLR 253
           L  N L SLP +LA                     +L  L+L  N L+  S  A LA L 
Sbjct: 224 LASNRLQSLPASLA------------------GLRSLRLLVLHSNLLA--SVPADLARLP 263

Query: 254 RLKKLSLDENRIIRIP 269
            L +L L +N++  +P
Sbjct: 264 LLTRLDLRDNQLRDLP 279



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 1/66 (1%)

Query: 141 ALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLT 200
           +L EL+LA N ++++       + L  L L  N L      DL  LP L  L L  N L 
Sbjct: 218 SLLELNLASNRLQSLPASLAGLRSLRLLVLHSN-LLASVPADLARLPLLTRLDLRDNQLR 276

Query: 201 SLPPNL 206
            LPP L
Sbjct: 277 DLPPEL 282


>gi|61742784 leucine rich repeat and death domain containing protein
           isoform 1 [Homo sapiens]
          Length = 910

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 50/139 (35%), Positives = 65/139 (46%), Gaps = 20/139 (14%)

Query: 142 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTS 201
           L  LDL+FN ++T+       + L  L LS N L+ E    LG LP L  L +T N L +
Sbjct: 127 LAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLS-ELPEALGALPALTFLTVTHNRLQT 185

Query: 202 LPPNLAVAEQEASVTSLTSKRYILRFPALETL---------MLDDNRLSN--PSCFASLA 250
           LPP L            T +R  L    L+TL         +L+ N  SN   S  ASLA
Sbjct: 186 LPPALGALS--------TLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLA 237

Query: 251 GLRRLKKLSLDENRIIRIP 269
           GLR L+ L L  N +  +P
Sbjct: 238 GLRSLRLLVLHSNLLASVP 256



 Score = 38.9 bits (89), Expect = 0.019
 Identities = 43/136 (31%), Positives = 59/136 (43%), Gaps = 21/136 (15%)

Query: 134 EAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLL 193
           EA    PAL  L +  N ++T+    G    L+ LDLS N L      ++G L  L  L 
Sbjct: 165 EALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDT-LPPEIGGLGSLLELN 223

Query: 194 LTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLR 253
           L  N L SLP +LA                     +L  L+L  N L+  S  A LA L 
Sbjct: 224 LASNRLQSLPASLA------------------GLRSLRLLVLHSNLLA--SVPADLARLP 263

Query: 254 RLKKLSLDENRIIRIP 269
            L +L L +N++  +P
Sbjct: 264 LLTRLDLRDNQLRDLP 279



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 1/66 (1%)

Query: 141 ALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLT 200
           +L EL+LA N ++++       + L  L L  N L      DL  LP L  L L  N L 
Sbjct: 218 SLLELNLASNRLQSLPASLAGLRSLRLLVLHSN-LLASVPADLARLPLLTRLDLRDNQLR 276

Query: 201 SLPPNL 206
            LPP L
Sbjct: 277 DLPPEL 282


>gi|6912638 ras suppressor protein 1 isoform 1 [Homo sapiens]
          Length = 277

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 32/208 (15%)

Query: 73  KESRRENQVDLP------GHILDQ--AFLLKH--HCVRKPSDLCTINAKENDFKHFHSVI 122
           +ESR +NQ ++        ++LD    F L H    V   + L  +     + K+   + 
Sbjct: 10  EESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLN 69

Query: 123 YINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAI-C 181
           + N     LP +   +   LK L+L  N + T+   +G    LE LDL++N+L+  ++  
Sbjct: 70  FFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPG 128

Query: 182 DLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLS 241
           +   L  LR L L+ N    LPP++                   +   L+ L L DN L 
Sbjct: 129 NFFYLTTLRALYLSDNDFEILPPDIG------------------KLTKLQILSLRDNDLI 170

Query: 242 NPSCFASLAGLRRLKKLSLDENRIIRIP 269
             S    +  L +LK+L +  NR+  +P
Sbjct: 171 --SLPKEIGELTQLKELHIQGNRLTVLP 196



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 2/84 (2%)

Query: 123 YINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICD 182
           Y N SEN LP   F+    L+ L L+ N  + +    G    L+ L L  N L +    +
Sbjct: 118 YNNLSENSLPGNFFY-LTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDL-ISLPKE 175

Query: 183 LGILPHLRVLLLTGNGLTSLPPNL 206
           +G L  L+ L + GN LT LPP L
Sbjct: 176 IGELTQLKELHIQGNRLTVLPPEL 199


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 57/244 (23%), Positives = 98/244 (40%), Gaps = 27/244 (11%)

Query: 452   KVKSEIPKVPKQPLVLHHP--RMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTEN 509
             K+K   PKVP++P  +     R++ TK   + + EP A++       K    E ++P   
Sbjct: 9831  KLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK---PKRVVAEEKVPVPR 9887

Query: 510   LEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSPERPSDEDSKSTES----IF 565
              E   P     VP   +        EE ++H+ +  V    E   +E+   TE     + 
Sbjct: 9888  KEVAPPVRVPEVP-KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVI 9946

Query: 566   LTQVSELPSSVI--HKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLT 623
               +V E+P   +   K  + + +K +  P   P   K    K+P   +P K         
Sbjct: 9947  PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPV-LIPKK--------- 9996

Query: 624   AKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPK 683
              KP PA + P+  +K     +  +  P    +   K+  + K  V ++K    +P+P PK
Sbjct: 9997  EKPPPAKV-PEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKK----VPVPAPK 10051

Query: 684   KTRA 687
             K  A
Sbjct: 10052 KVEA 10055



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 65/293 (22%), Positives = 102/293 (34%), Gaps = 39/293 (13%)

Query: 432   IRRKIVKPKHHVLMSRKESWKVK-SEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELA 490
             + +KI + K  V + +KE+   K  E+PK   +  VL   +     +  + +LE +  +A
Sbjct: 10295 VSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVA 10354

Query: 491   EDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSP 550
                       +E E+    +E   P    F  +         H  E    L     R+  
Sbjct: 10355 FRQEVVVKERLELEVVEAEVE-EIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQH--RVEE 10411

Query: 551   ERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEK--DQKKPPTAPREVKGTRRKLPT 608
             E   ++  +  E     +V             E+ EK    KKPPT     K   RK P 
Sbjct: 10412 EHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPT-----KVVPRKEPP 10466

Query: 609   AFLPS--KYHGYEELLTAKPDPAF--------IEPKGIQKNAQALQQMLKHPLLCHSSKP 658
             A +P   K    EE +    +P          + PK +    +      K P    +  P
Sbjct: 10467 AKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKP---EAPPP 10523

Query: 659   KLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAV 711
             K+    K  V ++K    +P+PPPKK               P  + E P  AV
Sbjct: 10524 KVPEAPKEVVPEKK----VPVPPPKKPEV-----------PPTKVPEVPKAAV 10561



 Score = 31.6 bits (70), Expect = 3.0
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 15/119 (12%)

Query: 568   QVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTR-RKLPTAFLPSKYHGYEELLTAKP 626
             +V E P  V+        EK    PP    EV  T+  ++P A +P K     E +  KP
Sbjct: 10524 KVPEAPKEVV-------PEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKK--VPEAIPPKP 10574

Query: 627   DPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQR-IPIPPPKK 684
             +    E     K     +++   P      KP++  ++ P   KE   ++ +P+PPPKK
Sbjct: 10575 ESPPPEVPEAPKEVVPEKKVPAAP----PKKPEVTPVKVPEAPKEVVPEKKVPVPPPKK 10629



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 56/292 (19%), Positives = 106/292 (36%), Gaps = 46/292 (15%)

Query: 454   KSEIP--KVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLE 511
             K E+P  KVP+ P V    +      P K    PE+   E     +  ++E E P E +E
Sbjct: 10629 KPEVPPTKVPEVPKVAVPEKKVPEAIPPK----PESPPPEVFEEPEEVALE-EPPAEVVE 10683

Query: 512   GHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSPERPSDEDSKSTESIFL----- 566
                P+    V +PP        +   ++   +      PE P +   +    + +     
Sbjct: 10684 EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPE 10743

Query: 567   ---TQVSELPSSVIHKDDLELKEKDQKKPPTAPR-EVKGTRRKLPTAFLPSKYHG----- 617
                 +V E+P  V+ +  + + +K +  P   P    K    + P   +P +        
Sbjct: 10744 APPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEV 10803

Query: 618   YEE-----------------LLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKL 660
             YEE                 +  A+ +   + P  + +  + +    K P++    KP+ 
Sbjct: 10804 YEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVI---KKPEA 10860

Query: 661   DTLQKP----YVHKEKRAQRIPIPPPKKTRAQLLDDIF-IRLRDPRNITEAP 707
                ++P     + K K   R P PPP   +  + + IF ++    + + E P
Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKP 10912


>gi|20143971 toll-like receptor 6 [Homo sapiens]
          Length = 796

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 57/216 (26%), Positives = 91/216 (42%), Gaps = 46/216 (21%)

Query: 86  HILDQAFLLKH---HCVRKPSDLCTINAKENDFKHF------HSVIYINASENLLPLEAF 136
           HI +Q FL      + V    ++  +   +  F H        +  ++N ++N+     F
Sbjct: 311 HITNQVFLFSQTALYTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFLNFTQNVFTDSIF 370

Query: 137 H---TFPALKELDLAFNGIKTIYVKYG----DFKLLEFLDLSFNSLT----------VEA 179
               T   L+ L L  NG+K ++ K G    D   LE LD+S+NSL           VE+
Sbjct: 371 EKCSTLVKLETLILQKNGLKDLF-KVGLMTKDMPSLEILDVSWNSLESGRHKENCTWVES 429

Query: 180 ICDLGIL-------------PHLRVLLLTGNGLTSLPPNL----AVAEQEASVTSLTSKR 222
           I  L +              P ++VL L  N + S+P  +    A+ E   +  SLT   
Sbjct: 430 IVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSLTDLP 489

Query: 223 YILRFPALETLMLDDNRLSNPSC--FASLAGLRRLK 256
               F +L  L++D N +S+PS   F S   +R +K
Sbjct: 490 GCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIK 525



 Score = 35.4 bits (80), Expect = 0.21
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 3/82 (3%)

Query: 115 FKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYV--KYGDFKLLEFLDLSF 172
           FK    + Y++ S N L   + H   + + LDL+FN  K + +  ++G+   L FL LS 
Sbjct: 96  FKFNQDLEYLDLSHNQLQKISCHPIVSFRHLDLSFNDFKALPICKEFGNLSQLNFLGLSA 155

Query: 173 NSLTVEAICDLGILPHLRVLLL 194
             L    +  +  L HL  +LL
Sbjct: 156 MKLQKLDLLPIAHL-HLSYILL 176


>gi|157694513 leucine-rich repeat-containing G protein-coupled
           receptor 4 [Homo sapiens]
          Length = 951

 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 51/143 (35%), Positives = 64/143 (44%), Gaps = 25/143 (17%)

Query: 131 LPLEAFHTFPALKELDLAFNGIKTIYVK-YGDFKLLEFLDLSFNSLTV---EAICDLGIL 186
           LP +AF  FP L+EL LA N +  I+ K     K L+ L L  N L     EAI  L  L
Sbjct: 72  LPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSAL 131

Query: 187 PHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCF 246
             LR   L  N +TS+P        E S   L   R+         L LDDN L+     
Sbjct: 132 QSLR---LDANHITSVP--------EDSFEGLVQLRH---------LWLDDNSLTEVPVH 171

Query: 247 ASLAGLRRLKKLSLDENRIIRIP 269
             L+ L  L+ L+L  N+I  IP
Sbjct: 172 -PLSNLPTLQALTLALNKISSIP 193



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 45/191 (23%), Positives = 74/191 (38%), Gaps = 42/191 (21%)

Query: 94  LKHHCVRKPSDLCTINAKENDFKHFHSVI----------YINASENLLPLEAFHTFPALK 143
           L  HC     +L T++   N+   F   I          + + S +++P  AF   P L+
Sbjct: 216 LSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLR 275

Query: 144 ELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILP------HLRVLLLTGN 197
            + L  N +  +    G+       DL  +SL +     +   P      HL  L LTG 
Sbjct: 276 TIHLYDNPLSFV----GNSAFHNLSDL--HSLVIRGASMVQQFPNLTGTVHLESLTLTGT 329

Query: 198 GLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKK 257
            ++S+P NL   ++                  L TL L  N + +     S  G   L++
Sbjct: 330 KISSIPNNLCQEQK-----------------MLRTLDLSYNNIRD---LPSFNGCHALEE 369

Query: 258 LSLDENRIIRI 268
           +SL  N+I +I
Sbjct: 370 ISLQRNQIYQI 380


>gi|16751843 toll-like receptor 5 [Homo sapiens]
          Length = 858

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 70/275 (25%), Positives = 115/275 (41%), Gaps = 43/275 (15%)

Query: 124 INASENLLP---LEAFHTFPALKELDLAFNGIKTIYVKYGDF-KLLEFLDLSFNSLTVEA 179
           +N S NLL       F+  P +  +DL  N I  I  +   F + L+ LDL  N+LT   
Sbjct: 341 LNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTT-- 398

Query: 180 ICDLGILPHLRVLLLTGNGLTSLPPNLAVAE----QEASVTSLTSKRYILRFPALETLML 235
              +  +P +  + L+GN L +LP     A      E  + +L    ++LR P L+ L+L
Sbjct: 399 ---IHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQILIL 455

Query: 236 DDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQL-YDESVDWNGGRGSPHKEP 294
           + NR S+ S   + +    L++L L EN          +QL ++  + W+   G  H + 
Sbjct: 456 NQNRFSSCSGDQTPSENPSLEQLFLGEN---------MLQLAWETELCWDVFEGLSHLQV 506

Query: 295 QFMLQSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEIL 354
            ++  +    L          +  +  + +R  V+  +              LP   EIL
Sbjct: 507 LYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN-------------DLPANLEIL 553

Query: 355 PVKSLKARNQTLAP---PFPELRYLSLAYNKIAKE 386
            +    +RNQ LAP    F  L  L + +NK   E
Sbjct: 554 DI----SRNQLLAPNPDVFVSLSVLDITHNKFICE 584


>gi|34577083 ras suppressor protein 1 isoform 2 [Homo sapiens]
          Length = 224

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 22/157 (14%)

Query: 114 DFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFN 173
           + K+   + + N     LP +   +   LK L+L  N + T+   +G    LE LDL++N
Sbjct: 8   ELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYN 66

Query: 174 SLTVEAI-CDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALET 232
           +L+  ++  +   L  LR L L+ N    LPP++                   +   L+ 
Sbjct: 67  NLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG------------------KLTKLQI 108

Query: 233 LMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269
           L L DN L   S    +  L +LK+L +  NR+  +P
Sbjct: 109 LSLRDNDLI--SLPKEIGELTQLKELHIQGNRLTVLP 143



 Score = 39.7 bits (91), Expect = 0.011
 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 2/84 (2%)

Query: 123 YINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICD 182
           Y N SEN LP   F+    L+ L L+ N  + +    G    L+ L L  N L +    +
Sbjct: 65  YNNLSENSLPGNFFY-LTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDL-ISLPKE 122

Query: 183 LGILPHLRVLLLTGNGLTSLPPNL 206
           +G L  L+ L + GN LT LPP L
Sbjct: 123 IGELTQLKELHIQGNRLTVLPPEL 146


>gi|33285015 leucine rich repeat containing 28 [Homo sapiens]
          Length = 367

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 49/167 (29%), Positives = 74/167 (44%), Gaps = 14/167 (8%)

Query: 111 KENDFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDL 170
           K+   ++   +     S   LP       P L EL L  N I  +    G    L+ LDL
Sbjct: 36  KDEGLQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDL 95

Query: 171 SFNSLTVEAIC-DLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFP- 228
           S N+L  E +C ++G L  LR L L  N L  LPP +   ++  ++   T++  +L  P 
Sbjct: 96  SDNAL--EIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNR--LLTLPE 151

Query: 229 ------ALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269
                 +L+ L +D NRL        L  L  L +LS+  NR+  +P
Sbjct: 152 RLHMCLSLQYLTVDRNRLWYVP--RHLCQLPSLNELSMAGNRLAFLP 196


>gi|4504379 leucine-rich repeat-containing G protein-coupled
           receptor 5 [Homo sapiens]
          Length = 907

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 36/112 (32%), Positives = 52/112 (46%), Gaps = 12/112 (10%)

Query: 167 FLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRY--- 223
           +LDLS N+++      L  L  L  L L GN LT +P           V  L + +    
Sbjct: 70  YLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHV 129

Query: 224 ----ILRFPALETLMLDDNRLS--NPSCFASLAGLRRLKKLSLDENRIIRIP 269
               +    +L++L LD N +S   PSCF   +GL  L+ L LD+N +  IP
Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCF---SGLHSLRHLWLDDNALTEIP 178


>gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo
           sapiens]
          Length = 516

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/133 (34%), Positives = 60/133 (45%), Gaps = 19/133 (14%)

Query: 134 EAFHTFPALKELDLAFNGIKTIYVK-YGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVL 192
           E F+    L+ L L  N ++TI V+ + D + LEFLDLS N L   A      L  LR L
Sbjct: 151 ELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLREL 210

Query: 193 LLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGL 252
            L  N LT +  N A               + LR  +L TL L  N++SN +C       
Sbjct: 211 HLEHNQLTKI--NFA---------------HFLRLSSLHTLFLQWNKISNLTCGMEWT-W 252

Query: 253 RRLKKLSLDENRI 265
             L+KL L  N I
Sbjct: 253 GTLEKLDLTGNEI 265


>gi|40217825 slit and trk like 6 [Homo sapiens]
          Length = 841

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 44/156 (28%), Positives = 66/156 (42%), Gaps = 22/156 (14%)

Query: 113 NDFKHFHSVIYINAS-ENLLPLE--AFHTFPALKELDLAFNGIKTIYVK-YGDFKLLEFL 168
           NDF    + I I+    N+  +E  AF+    LK+L +  N ++ +    +   + LEFL
Sbjct: 82  NDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFL 141

Query: 169 DLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFP 228
               N +TV        L  L+VL+L  N + SLPPN                  I RF 
Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPN------------------IFRFV 183

Query: 229 ALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENR 264
            L  L L  N+L        L  + R+  L L++N+
Sbjct: 184 PLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNK 219


>gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens]
          Length = 522

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/153 (30%), Positives = 69/153 (45%), Gaps = 25/153 (16%)

Query: 135 AFHTFPALKELDLAFNGIKTI-YVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLL 193
           +F T P LK LDL+ N +KT+    + + K+LE L L  N ++       G L  L+ L 
Sbjct: 112 SFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLY 171

Query: 194 LTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLD--DNRL-SNPSCFASLA 250
           L+GN LT  P +L                Y+ RF   E + LD   NR+ S P    +L 
Sbjct: 172 LSGNFLTQFPMDL----------------YVGRFKLAELMFLDVSYNRIPSMPMHHINLV 215

Query: 251 GLRRLKKLSLDENRIIRIPYLQQVQLYDESVDW 283
             ++L+ + L  N     P++    LY   V W
Sbjct: 216 PGKQLRGIYLHGN-----PFVCDCSLYSLLVFW 243


>gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens]
          Length = 522

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 47/153 (30%), Positives = 69/153 (45%), Gaps = 25/153 (16%)

Query: 135 AFHTFPALKELDLAFNGIKTI-YVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLL 193
           +F T P LK LDL+ N +KT+    + + K+LE L L  N ++       G L  L+ L 
Sbjct: 112 SFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLY 171

Query: 194 LTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLD--DNRL-SNPSCFASLA 250
           L+GN LT  P +L                Y+ RF   E + LD   NR+ S P    +L 
Sbjct: 172 LSGNFLTQFPMDL----------------YVGRFKLAELMFLDVSYNRIPSMPMHHINLV 215

Query: 251 GLRRLKKLSLDENRIIRIPYLQQVQLYDESVDW 283
             ++L+ + L  N     P++    LY   V W
Sbjct: 216 PGKQLRGIYLHGN-----PFVCDCSLYSLLVFW 243


>gi|110825984 malignant fibrous histiocytoma amplified sequence 1
           [Homo sapiens]
          Length = 1052

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 46/138 (33%), Positives = 70/138 (50%), Gaps = 16/138 (11%)

Query: 141 ALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSL-TVEA-ICDLGILPHLRVLLLTGNG 198
           AL+ELD++ N ++ +       + L+ L LS   L T+ A  C+L     L  L+L  NG
Sbjct: 205 ALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELA---SLESLMLDNNG 261

Query: 199 LTSLPPNLAVAEQEASVTSLTSKRY------ILRFPALETLMLDDNRLSN-PSCFASLAG 251
           L +LP   +   Q   + +L+S  +      +L    LE L L  N+L++ PS    ++G
Sbjct: 262 LQALPAQFSCL-QRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSL---ISG 317

Query: 252 LRRLKKLSLDENRIIRIP 269
           L RL  L LD NRI  +P
Sbjct: 318 LGRLLTLWLDNNRIRYLP 335



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 50/160 (31%), Positives = 70/160 (43%), Gaps = 13/160 (8%)

Query: 119 HSVIYINASENLLPLEAFHTFPALKEL---DLAFNGIKTIYVKYGDFKLLEFLDLSFNSL 175
           H +  ++ S N L         AL+EL   +L+ N +  +  + G    LE LD+SFN L
Sbjct: 111 HHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRL 170

Query: 176 TVEAICDLGILPHLRVLLLTGNGLTSLPPNL--AVAEQEASVTSLTSK---RYILRFPAL 230
                  L  L  LR L +  N LT+ P  L   VA +E  V+S   +     I    AL
Sbjct: 171 -AHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRAL 229

Query: 231 ETLMLDDNRLSN-PSCFASLAGLRRLKKLSLDENRIIRIP 269
           + L L    L   P+ F  LA    L+ L LD N +  +P
Sbjct: 230 KILWLSGAELGTLPAGFCELAS---LESLMLDNNGLQALP 266



 Score = 34.3 bits (77), Expect = 0.46
 Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 11/113 (9%)

Query: 165 LEFLDLSFNSLTVEAICDLG-ILPHLRVLLLTGNGLTSLPPNLA-----VAEQEASVTSL 218
           +E L+L  N L  E    LG  L  LRVL+L  N    LPP +A     + E + S   L
Sbjct: 65  IEALNLGNNGLE-EVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRL 123

Query: 219 TS--KRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269
           T+     +     L  L L  N+L  P+  A L  L  L++L +  NR+  +P
Sbjct: 124 TALGAEVVSALRELRKLNLSHNQL--PALPAQLGALAHLEELDVSFNRLAHLP 174



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 9/134 (6%)

Query: 186 LPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPA-------LETLMLDDN 238
           L  +  L L  NGL  +P  L  A     V  L   R+    PA       L  L +  N
Sbjct: 62  LGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHN 121

Query: 239 RLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFML 298
           RL+       ++ LR L+KL+L  N++  +P       + E +D +  R   H       
Sbjct: 122 RLTALGA-EVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNR-LAHLPDSLSC 179

Query: 299 QSKPRMLEDSDEQL 312
            S+ R L+    QL
Sbjct: 180 LSRLRTLDVDHNQL 193


>gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2
           [Homo sapiens]
          Length = 1065

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 11/159 (6%)

Query: 120 SVIYINASENLLP---LEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSL- 175
           ++  ++   N++P    +A   +PAL+ LDL+ N I  I         L++L+LS N + 
Sbjct: 121 NITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRIT 180

Query: 176 TVEAICDLGILPHLRVLLLTGNGLTSLP------PNLAVAEQEASVTSLTSKRYILRFPA 229
           T+EA C   +   L V+ L  N ++ +P      P+L   E + +   +          +
Sbjct: 181 TLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDS 240

Query: 230 LETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRI 268
           L +L +  N +S      +  GL  +++L L+ N + R+
Sbjct: 241 LRSLKMQRNGISKLK-DGAFFGLNNMEELELEHNNLTRV 278


>gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens]
          Length = 713

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 68/278 (24%), Positives = 109/278 (39%), Gaps = 63/278 (22%)

Query: 131 LPLEAFHTFPALKELDLAFNGIKTIYVKYGDF-KLLEFLDLSFNSLTVEAICD---LGIL 186
           +P  A    P LK LDL  N ++   V  GDF  +L   +L  N++      D   L  L
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQR--VGPGDFANMLHLKELGLNNMEELVSIDKFALVNL 309

Query: 187 PHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCF 246
           P L  L +T N      P L          S    R     P +ETLML++N LS     
Sbjct: 310 PELTKLDITNN------PRL----------SFIHPRAFHHLPQMETLMLNNNALS----- 348

Query: 247 ASLAGLRRLKKLSLDENRIIRIPYLQQVQLY------DESVDWNGGRGSPHK--EPQFML 298
                       +L +  +  +P LQ+V L+      D  + W    G+  +  EPQ  L
Sbjct: 349 ------------ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTL 396

Query: 299 QSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKS 358
            ++P  L    ++L    +P ++  D    + S              S PP  ++   +S
Sbjct: 397 CAEPPDL----QRLPVREVPFREMTDHCLPLISPR------------SFPPSLQVASGES 440

Query: 359 LKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFP 396
           +    + LA P PE+ +++ A  ++    A     ++P
Sbjct: 441 MVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYP 478



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 22/165 (13%)

Query: 109 NAKENDFKHFHSVIYINASENLLPLEAFHTFPALKEL-DLAFNGIKTIYVKYGDFK-LLE 166
           +A++ DF     ++ ++  EN L     H+F  L  L +L  N  +   +    F  L  
Sbjct: 107 DARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSN 166

Query: 167 FLDLSFNSLTVEAICD--LGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYI 224
            L L  NS  + AI      +LP+L +L++ GN + ++         + +   L +    
Sbjct: 167 LLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAI--------LDMNFRPLAN---- 214

Query: 225 LRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269
                L +L+L    L   S +A L GL+ L+ LS  +N++ R+P
Sbjct: 215 -----LRSLVLAGMNLREISDYA-LEGLQSLESLSFYDNQLARVP 253



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 24/122 (19%)

Query: 168 LDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRF 227
           LDLS NS +    CD   LP L  L L  N LT L        ++ S   L S       
Sbjct: 98  LDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRL--------EDHSFAGLAS------- 142

Query: 228 PALETLMLDDNRLSN--PSCFASLAGLRRLKKLS-----LDENRIIRIPYLQQVQLYDES 280
             L+ L L+ N+L    P  F+ L+ L RL   S     +D      +P L+ + +    
Sbjct: 143 --LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNK 200

Query: 281 VD 282
           VD
Sbjct: 201 VD 202


>gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens]
          Length = 713

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 68/278 (24%), Positives = 109/278 (39%), Gaps = 63/278 (22%)

Query: 131 LPLEAFHTFPALKELDLAFNGIKTIYVKYGDF-KLLEFLDLSFNSLTVEAICD---LGIL 186
           +P  A    P LK LDL  N ++   V  GDF  +L   +L  N++      D   L  L
Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQR--VGPGDFANMLHLKELGLNNMEELVSIDKFALVNL 309

Query: 187 PHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCF 246
           P L  L +T N      P L          S    R     P +ETLML++N LS     
Sbjct: 310 PELTKLDITNN------PRL----------SFIHPRAFHHLPQMETLMLNNNALS----- 348

Query: 247 ASLAGLRRLKKLSLDENRIIRIPYLQQVQLY------DESVDWNGGRGSPHK--EPQFML 298
                       +L +  +  +P LQ+V L+      D  + W    G+  +  EPQ  L
Sbjct: 349 ------------ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTL 396

Query: 299 QSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKS 358
            ++P  L    ++L    +P ++  D    + S              S PP  ++   +S
Sbjct: 397 CAEPPDL----QRLPVREVPFREMTDHCLPLISPR------------SFPPSLQVASGES 440

Query: 359 LKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFP 396
           +    + LA P PE+ +++ A  ++    A     ++P
Sbjct: 441 MVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYP 478



 Score = 34.7 bits (78), Expect = 0.36
 Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 22/165 (13%)

Query: 109 NAKENDFKHFHSVIYINASENLLPLEAFHTFPALKEL-DLAFNGIKTIYVKYGDFK-LLE 166
           +A++ DF     ++ ++  EN L     H+F  L  L +L  N  +   +    F  L  
Sbjct: 107 DARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSN 166

Query: 167 FLDLSFNSLTVEAICD--LGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYI 224
            L L  NS  + AI      +LP+L +L++ GN + ++         + +   L +    
Sbjct: 167 LLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAI--------LDMNFRPLAN---- 214

Query: 225 LRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269
                L +L+L    L   S +A L GL+ L+ LS  +N++ R+P
Sbjct: 215 -----LRSLVLAGMNLREISDYA-LEGLQSLESLSFYDNQLARVP 253



 Score = 32.3 bits (72), Expect = 1.8
 Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 24/122 (19%)

Query: 168 LDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRF 227
           LDLS NS +    CD   LP L  L L  N LT L        ++ S   L S       
Sbjct: 98  LDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRL--------EDHSFAGLAS------- 142

Query: 228 PALETLMLDDNRLSN--PSCFASLAGLRRLKKLS-----LDENRIIRIPYLQQVQLYDES 280
             L+ L L+ N+L    P  F+ L+ L RL   S     +D      +P L+ + +    
Sbjct: 143 --LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNK 200

Query: 281 VD 282
           VD
Sbjct: 201 VD 202


>gi|38202222 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 43/125 (34%), Positives = 58/125 (46%), Gaps = 24/125 (19%)

Query: 142 LKELDLAFNGIKTI-YVKYGDFKLLEFLDLSFNSLTVEAICDLGILP--HLRVLLLTGNG 198
           +KEL L  N I+TI Y        LE L L  NS++  +I +       +LR+L L+ N 
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165

Query: 199 LTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKL 258
           L+++P  L                       +E L LDDNR+S  S   SL GL  LK+L
Sbjct: 166 LSTIPWGLP--------------------RTIEELRLDDNRISTISS-PSLQGLTSLKRL 204

Query: 259 SLDEN 263
            LD N
Sbjct: 205 VLDGN 209


>gi|7019383 fibronectin leucine rich transmembrane protein 3
           precursor [Homo sapiens]
          Length = 649

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 43/125 (34%), Positives = 58/125 (46%), Gaps = 24/125 (19%)

Query: 142 LKELDLAFNGIKTI-YVKYGDFKLLEFLDLSFNSLTVEAICDLGILP--HLRVLLLTGNG 198
           +KEL L  N I+TI Y        LE L L  NS++  +I +       +LR+L L+ N 
Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165

Query: 199 LTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKL 258
           L+++P  L                       +E L LDDNR+S  S   SL GL  LK+L
Sbjct: 166 LSTIPWGLP--------------------RTIEELRLDDNRISTISS-PSLQGLTSLKRL 204

Query: 259 SLDEN 263
            LD N
Sbjct: 205 VLDGN 209


>gi|62241040 leucine rich repeat containing 8 family, member A [Homo
           sapiens]
          Length = 810

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 12/121 (9%)

Query: 97  HCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPA-----------LKEL 145
           H +    +L  I+ K+N+ K    +I       L  L+ ++   A           L+ L
Sbjct: 608 HSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERL 667

Query: 146 DLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPN 205
            L  N I+ I  +    + L +LDLS N+LT     D+G+L +L+ L +T N + +LPP 
Sbjct: 668 YLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLP-ADIGLLQNLQNLAITANRIETLPPE 726

Query: 206 L 206
           L
Sbjct: 727 L 727


>gi|187829877 leucine rich repeat containing 8 family, member A
           [Homo sapiens]
          Length = 810

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 12/121 (9%)

Query: 97  HCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPA-----------LKEL 145
           H +    +L  I+ K+N+ K    +I       L  L+ ++   A           L+ L
Sbjct: 608 HSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERL 667

Query: 146 DLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPN 205
            L  N I+ I  +    + L +LDLS N+LT     D+G+L +L+ L +T N + +LPP 
Sbjct: 668 YLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLP-ADIGLLQNLQNLAITANRIETLPPE 726

Query: 206 L 206
           L
Sbjct: 727 L 727


>gi|187829871 leucine rich repeat containing 8 family, member A
           [Homo sapiens]
          Length = 810

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 12/121 (9%)

Query: 97  HCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPA-----------LKEL 145
           H +    +L  I+ K+N+ K    +I       L  L+ ++   A           L+ L
Sbjct: 608 HSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERL 667

Query: 146 DLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPN 205
            L  N I+ I  +    + L +LDLS N+LT     D+G+L +L+ L +T N + +LPP 
Sbjct: 668 YLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLP-ADIGLLQNLQNLAITANRIETLPPE 726

Query: 206 L 206
           L
Sbjct: 727 L 727


>gi|61966761 leucine rich repeat containing 26 [Homo sapiens]
          Length = 334

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 39/112 (34%), Positives = 52/112 (46%), Gaps = 18/112 (16%)

Query: 131 LPLEAFHTFPALKELDLAFNGIKTIYVK-YGDFKLLEFLDLSFNSLTVEAICDLGILPHL 189
           LP  AF    AL+ LDL  NG+ +++V+ +     L+ LDLS N L   A      L  L
Sbjct: 86  LPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRAL 145

Query: 190 RVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLS 241
           R L L GN L  L P        A++ +L         P L +L L DN L+
Sbjct: 146 RNLSLAGNRLARLEP--------AALGAL---------PLLRSLSLQDNELA 180



 Score = 30.8 bits (68), Expect = 5.1
 Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 20/115 (17%)

Query: 184 GILPHLRVLLLTGNGLTSLPPNL-----AVAEQEASVTSLTS--KRYILRFPALETLMLD 236
           G+   LR LLL  N + +LPP       A+   +     L S   R      AL+ L L 
Sbjct: 68  GLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLS 127

Query: 237 DNRLS--NPSCFASLAGLRRLKKLSLDENRIIR--------IPYLQQVQLYDESV 281
            N+L    P  FA    LR L+ LSL  NR+ R        +P L+ + L D  +
Sbjct: 128 ANQLEALAPGTFAP---LRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNEL 179


>gi|45827729 scribble isoform b [Homo sapiens]
          Length = 1630

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 10/160 (6%)

Query: 117 HFHSVIYINASENLLPLEAFHTFPALKELDLA-FNGIKTIYVKYGDFKLLEFLDLSFNSL 175
           +F  ++ ++ S N +P E   +    K L++A F+G     +  G  +L     L+ N +
Sbjct: 80  NFMQLVELDVSRNDIP-EIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDV 138

Query: 176 TVEAIC-DLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYIL-----RFPA 229
           +++A+  D+G L +L  L L  N L SLP +L+   +   +    +   +L       P 
Sbjct: 139 SLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPN 198

Query: 230 LETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269
           L  L LD N+LS  +    L  LRRL  L + ENR+  +P
Sbjct: 199 LRELWLDRNQLS--ALPPELGNLRRLVCLDVSENRLEELP 236



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 14/135 (10%)

Query: 142 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICD-LGILPHLRVLLLTGNGLT 200
           L  L+L  N +K++         LE LDL  N L  E + D LG LP+LR L L  N L+
Sbjct: 153 LVTLELRENLLKSLPASLSFLVKLEQLDLGGNDL--EVLPDTLGALPNLRELWLDRNQLS 210

Query: 201 SLPPNLAVAEQEASVTSLTSKRYILRFPA-------LETLMLDDNRLSNPSCFASLAGLR 253
           +LPP L    +   +    S+  +   PA       L  L+L  N L        +  L+
Sbjct: 211 ALPPELGNLRRLVCLD--VSENRLEELPAELGGLVLLTDLLLSQNLLRRLP--DGIGQLK 266

Query: 254 RLKKLSLDENRIIRI 268
           +L  L +D+NR+  +
Sbjct: 267 QLSILKVDQNRLCEV 281



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 10/136 (7%)

Query: 140 PALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGL 199
           P L+EL L  N +  +  + G+ + L  LD+S N L  E   +LG L  L  LLL+ N L
Sbjct: 197 PNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLE-ELPAELGGLVLLTDLLLSQNLL 255

Query: 200 TSLPPNLAVAEQEASVTSLTSKRYILRFPA------LETLMLDDNRLSNPSCFASLAGLR 253
             LP  +   +Q  S+  +   R      A      L  L+L +N L   +   SL  L 
Sbjct: 256 RRLPDGIGQLKQ-LSILKVDQNRLCEVTEAIGDCENLSELILTENLLM--ALPRSLGKLT 312

Query: 254 RLKKLSLDENRIIRIP 269
           +L  L++D N +  +P
Sbjct: 313 KLTNLNVDRNHLEALP 328


>gi|45827731 scribble isoform a [Homo sapiens]
          Length = 1655

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 10/160 (6%)

Query: 117 HFHSVIYINASENLLPLEAFHTFPALKELDLA-FNGIKTIYVKYGDFKLLEFLDLSFNSL 175
           +F  ++ ++ S N +P E   +    K L++A F+G     +  G  +L     L+ N +
Sbjct: 80  NFMQLVELDVSRNDIP-EIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDV 138

Query: 176 TVEAIC-DLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYIL-----RFPA 229
           +++A+  D+G L +L  L L  N L SLP +L+   +   +    +   +L       P 
Sbjct: 139 SLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPN 198

Query: 230 LETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269
           L  L LD N+LS  +    L  LRRL  L + ENR+  +P
Sbjct: 199 LRELWLDRNQLS--ALPPELGNLRRLVCLDVSENRLEELP 236



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 14/135 (10%)

Query: 142 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICD-LGILPHLRVLLLTGNGLT 200
           L  L+L  N +K++         LE LDL  N L  E + D LG LP+LR L L  N L+
Sbjct: 153 LVTLELRENLLKSLPASLSFLVKLEQLDLGGNDL--EVLPDTLGALPNLRELWLDRNQLS 210

Query: 201 SLPPNLAVAEQEASVTSLTSKRYILRFPA-------LETLMLDDNRLSNPSCFASLAGLR 253
           +LPP L    +   +    S+  +   PA       L  L+L  N L        +  L+
Sbjct: 211 ALPPELGNLRRLVCLD--VSENRLEELPAELGGLVLLTDLLLSQNLLRRLP--DGIGQLK 266

Query: 254 RLKKLSLDENRIIRI 268
           +L  L +D+NR+  +
Sbjct: 267 QLSILKVDQNRLCEV 281



 Score = 37.7 bits (86), Expect = 0.042
 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 10/136 (7%)

Query: 140 PALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGL 199
           P L+EL L  N +  +  + G+ + L  LD+S N L  E   +LG L  L  LLL+ N L
Sbjct: 197 PNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLE-ELPAELGGLVLLTDLLLSQNLL 255

Query: 200 TSLPPNLAVAEQEASVTSLTSKRYILRFPA------LETLMLDDNRLSNPSCFASLAGLR 253
             LP  +   +Q  S+  +   R      A      L  L+L +N L   +   SL  L 
Sbjct: 256 RRLPDGIGQLKQ-LSILKVDQNRLCEVTEAIGDCENLSELILTENLLM--ALPRSLGKLT 312

Query: 254 RLKKLSLDENRIIRIP 269
           +L  L++D N +  +P
Sbjct: 313 KLTNLNVDRNHLEALP 328


>gi|194394161 leucine rich repeat containing 57 [Homo sapiens]
          Length = 239

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 51/161 (31%), Positives = 72/161 (44%), Gaps = 9/161 (5%)

Query: 125 NASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLG 184
           N  E+L PL     F  LK L L  N +  +  +  + K LE L L+ N L  E     G
Sbjct: 48  NKIESLPPL-LIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLR-ELPSTFG 105

Query: 185 ILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFP----ALETLMLDDNRL 240
            L  L+ L L+GN L +LPP L  + +   V  L SK  I   P     L+ + L+ N+ 
Sbjct: 106 QLSALKTLSLSGNQLGALPPQLC-SLRHLDVMDL-SKNQIRSIPDSVGELQVIELNLNQN 163

Query: 241 SNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESV 281
                   ++   RLK L L+EN  + +  L Q  L D  +
Sbjct: 164 QISQISVKISCCPRLKILRLEEN-CLELSMLPQSILSDSQI 203


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,025,104
Number of Sequences: 37866
Number of extensions: 1625832
Number of successful extensions: 5745
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 260
Number of HSP's that attempted gapping in prelim test: 5207
Number of HSP's gapped (non-prelim): 681
length of query: 792
length of database: 18,247,518
effective HSP length: 110
effective length of query: 682
effective length of database: 14,082,258
effective search space: 9604099956
effective search space used: 9604099956
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press