BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|150378449 X-ray radiation resistance associated 1 [Homo sapiens] (792 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|150378449 X-ray radiation resistance associated 1 [Homo sapiens] 1595 0.0 gi|150417978 platelet glycoprotein Ib alpha polypeptide precurso... 52 2e-06 gi|40217803 leucine rich repeat containing 8 family, member E [H... 49 2e-05 gi|61742786 leucine rich repeat and death domain containing prot... 49 2e-05 gi|61742784 leucine rich repeat and death domain containing prot... 49 2e-05 gi|6912638 ras suppressor protein 1 isoform 1 [Homo sapiens] 48 3e-05 gi|110349719 titin isoform N2-A [Homo sapiens] 48 4e-05 gi|20143971 toll-like receptor 6 [Homo sapiens] 47 9e-05 gi|157694513 leucine-rich repeat-containing G protein-coupled re... 47 9e-05 gi|16751843 toll-like receptor 5 [Homo sapiens] 46 2e-04 gi|34577083 ras suppressor protein 1 isoform 2 [Homo sapiens] 46 2e-04 gi|33285015 leucine rich repeat containing 28 [Homo sapiens] 45 2e-04 gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 45 3e-04 gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa... 45 3e-04 gi|40217825 slit and trk like 6 [Homo sapiens] 45 3e-04 gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens] 45 3e-04 gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens] 45 3e-04 gi|110825984 malignant fibrous histiocytoma amplified sequence 1... 44 4e-04 gi|7662320 leucine-rich repeats and immunoglobulin-like domains ... 44 4e-04 gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] 44 6e-04 gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] 44 6e-04 gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 44 8e-04 gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 44 8e-04 gi|62241040 leucine rich repeat containing 8 family, member A [H... 43 0.001 gi|187829877 leucine rich repeat containing 8 family, member A [... 43 0.001 gi|187829871 leucine rich repeat containing 8 family, member A [... 43 0.001 gi|61966761 leucine rich repeat containing 26 [Homo sapiens] 43 0.001 gi|45827729 scribble isoform b [Homo sapiens] 43 0.001 gi|45827731 scribble isoform a [Homo sapiens] 43 0.001 gi|194394161 leucine rich repeat containing 57 [Homo sapiens] 43 0.001 >gi|150378449 X-ray radiation resistance associated 1 [Homo sapiens] Length = 792 Score = 1595 bits (4129), Expect = 0.0 Identities = 792/792 (100%), Positives = 792/792 (100%) Query: 1 MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRE 60 MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRE Sbjct: 1 MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRE 60 Query: 61 SLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTINAKENDFKHFHS 120 SLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTINAKENDFKHFHS Sbjct: 61 SLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTINAKENDFKHFHS 120 Query: 121 VIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAI 180 VIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAI Sbjct: 121 VIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAI 180 Query: 181 CDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRL 240 CDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRL Sbjct: 181 CDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRL 240 Query: 241 SNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQS 300 SNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQS Sbjct: 241 SNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQS 300 Query: 301 KPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLK 360 KPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLK Sbjct: 301 KPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLK 360 Query: 361 ARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLK 420 ARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLK Sbjct: 361 ARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLK 420 Query: 421 SFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSK 480 SFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSK Sbjct: 421 SFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSK 480 Query: 481 DMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSH 540 DMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSH Sbjct: 481 DMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSH 540 Query: 541 LSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVK 600 LSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVK Sbjct: 541 LSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVK 600 Query: 601 GTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKL 660 GTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKL Sbjct: 601 GTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKL 660 Query: 661 DTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRL 720 DTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRL Sbjct: 661 DTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRL 720 Query: 721 VNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACPALSESQPKFGHFLEFMDE 780 VNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACPALSESQPKFGHFLEFMDE Sbjct: 721 VNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACPALSESQPKFGHFLEFMDE 780 Query: 781 FCQEPTASDSQG 792 FCQEPTASDSQG Sbjct: 781 FCQEPTASDSQG 792 >gi|150417978 platelet glycoprotein Ib alpha polypeptide precursor [Homo sapiens] Length = 639 Score = 52.4 bits (124), Expect = 2e-06 Identities = 46/140 (32%), Positives = 61/140 (43%), Gaps = 18/140 (12%) Query: 130 LLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHL 189 L L+ T P L LDL+ N ++++ + L LD+SFN LT + L L L Sbjct: 83 LTKLQVDGTLPVLGTLDLSHNQLQSLPLLGQTLPALTVLDVSFNRLTSLPLGALRGLGEL 142 Query: 190 RVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASL 249 + L L GN L +LPP L + P LE L L +N L+ L Sbjct: 143 QELYLKGNELKTLPPGL-----------------LTPTPKLEKLSLANNNLTELPA-GLL 184 Query: 250 AGLRRLKKLSLDENRIIRIP 269 GL L L L EN + IP Sbjct: 185 NGLENLDTLLLQENSLYTIP 204 >gi|40217803 leucine rich repeat containing 8 family, member E [Homo sapiens] Length = 796 Score = 48.9 bits (115), Expect = 2e-05 Identities = 49/180 (27%), Positives = 77/180 (42%), Gaps = 24/180 (13%) Query: 97 HCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIY 156 H V L ++ K+N + ++ L+ L +H N I + Sbjct: 599 HAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWH------------NQIAYVP 646 Query: 157 VKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLA-------VA 209 + LE L LS+N L LG+ LR+L ++ NGL SLPP + +A Sbjct: 647 EHVRKLRSLEQLYLSYNKLETLP-SQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLA 705 Query: 210 EQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269 ++ +L + + R L TL+L DN+LS S + LR L +L L NR+ +P Sbjct: 706 LSYNALEALPEELFFCR--KLRTLLLGDNQLSQLS--PHVGALRALSRLELKGNRLEALP 761 >gi|61742786 leucine rich repeat and death domain containing protein isoform 3 [Homo sapiens] Length = 893 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/139 (35%), Positives = 65/139 (46%), Gaps = 20/139 (14%) Query: 142 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTS 201 L LDL+FN ++T+ + L L LS N L+ E LG LP L L +T N L + Sbjct: 127 LAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLS-ELPEALGALPALTFLTVTHNRLQT 185 Query: 202 LPPNLAVAEQEASVTSLTSKRYILRFPALETL---------MLDDNRLSN--PSCFASLA 250 LPP L T +R L L+TL +L+ N SN S ASLA Sbjct: 186 LPPALGALS--------TLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLA 237 Query: 251 GLRRLKKLSLDENRIIRIP 269 GLR L+ L L N + +P Sbjct: 238 GLRSLRLLVLHSNLLASVP 256 Score = 38.9 bits (89), Expect = 0.019 Identities = 43/136 (31%), Positives = 59/136 (43%), Gaps = 21/136 (15%) Query: 134 EAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLL 193 EA PAL L + N ++T+ G L+ LDLS N L ++G L L L Sbjct: 165 EALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDT-LPPEIGGLGSLLELN 223 Query: 194 LTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLR 253 L N L SLP +LA +L L+L N L+ S A LA L Sbjct: 224 LASNRLQSLPASLA------------------GLRSLRLLVLHSNLLA--SVPADLARLP 263 Query: 254 RLKKLSLDENRIIRIP 269 L +L L +N++ +P Sbjct: 264 LLTRLDLRDNQLRDLP 279 Score = 31.6 bits (70), Expect = 3.0 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Query: 141 ALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLT 200 +L EL+LA N ++++ + L L L N L DL LP L L L N L Sbjct: 218 SLLELNLASNRLQSLPASLAGLRSLRLLVLHSN-LLASVPADLARLPLLTRLDLRDNQLR 276 Query: 201 SLPPNL 206 LPP L Sbjct: 277 DLPPEL 282 >gi|61742784 leucine rich repeat and death domain containing protein isoform 1 [Homo sapiens] Length = 910 Score = 48.5 bits (114), Expect = 2e-05 Identities = 50/139 (35%), Positives = 65/139 (46%), Gaps = 20/139 (14%) Query: 142 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTS 201 L LDL+FN ++T+ + L L LS N L+ E LG LP L L +T N L + Sbjct: 127 LAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLS-ELPEALGALPALTFLTVTHNRLQT 185 Query: 202 LPPNLAVAEQEASVTSLTSKRYILRFPALETL---------MLDDNRLSN--PSCFASLA 250 LPP L T +R L L+TL +L+ N SN S ASLA Sbjct: 186 LPPALGALS--------TLQRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLA 237 Query: 251 GLRRLKKLSLDENRIIRIP 269 GLR L+ L L N + +P Sbjct: 238 GLRSLRLLVLHSNLLASVP 256 Score = 38.9 bits (89), Expect = 0.019 Identities = 43/136 (31%), Positives = 59/136 (43%), Gaps = 21/136 (15%) Query: 134 EAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLL 193 EA PAL L + N ++T+ G L+ LDLS N L ++G L L L Sbjct: 165 EALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDT-LPPEIGGLGSLLELN 223 Query: 194 LTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLR 253 L N L SLP +LA +L L+L N L+ S A LA L Sbjct: 224 LASNRLQSLPASLA------------------GLRSLRLLVLHSNLLA--SVPADLARLP 263 Query: 254 RLKKLSLDENRIIRIP 269 L +L L +N++ +P Sbjct: 264 LLTRLDLRDNQLRDLP 279 Score = 31.6 bits (70), Expect = 3.0 Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 1/66 (1%) Query: 141 ALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLT 200 +L EL+LA N ++++ + L L L N L DL LP L L L N L Sbjct: 218 SLLELNLASNRLQSLPASLAGLRSLRLLVLHSN-LLASVPADLARLPLLTRLDLRDNQLR 276 Query: 201 SLPPNL 206 LPP L Sbjct: 277 DLPPEL 282 >gi|6912638 ras suppressor protein 1 isoform 1 [Homo sapiens] Length = 277 Score = 48.1 bits (113), Expect = 3e-05 Identities = 53/208 (25%), Positives = 89/208 (42%), Gaps = 32/208 (15%) Query: 73 KESRRENQVDLP------GHILDQ--AFLLKH--HCVRKPSDLCTINAKENDFKHFHSVI 122 +ESR +NQ ++ ++LD F L H V + L + + K+ + Sbjct: 10 EESREKNQPEVDMSDRGISNMLDVNGLFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLN 69 Query: 123 YINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAI-C 181 + N LP + + LK L+L N + T+ +G LE LDL++N+L+ ++ Sbjct: 70 FFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPG 128 Query: 182 DLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLS 241 + L LR L L+ N LPP++ + L+ L L DN L Sbjct: 129 NFFYLTTLRALYLSDNDFEILPPDIG------------------KLTKLQILSLRDNDLI 170 Query: 242 NPSCFASLAGLRRLKKLSLDENRIIRIP 269 S + L +LK+L + NR+ +P Sbjct: 171 --SLPKEIGELTQLKELHIQGNRLTVLP 196 Score = 39.7 bits (91), Expect = 0.011 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 123 YINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICD 182 Y N SEN LP F+ L+ L L+ N + + G L+ L L N L + + Sbjct: 118 YNNLSENSLPGNFFY-LTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDL-ISLPKE 175 Query: 183 LGILPHLRVLLLTGNGLTSLPPNL 206 +G L L+ L + GN LT LPP L Sbjct: 176 IGELTQLKELHIQGNRLTVLPPEL 199 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 47.8 bits (112), Expect = 4e-05 Identities = 57/244 (23%), Positives = 98/244 (40%), Gaps = 27/244 (11%) Query: 452 KVKSEIPKVPKQPLVLHHP--RMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTEN 509 K+K PKVP++P + R++ TK + + EP A++ K E ++P Sbjct: 9831 KLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK---PKRVVAEEKVPVPR 9887 Query: 510 LEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSPERPSDEDSKSTES----IF 565 E P VP + EE ++H+ + V E +E+ TE + Sbjct: 9888 KEVAPPVRVPEVP-KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVI 9946 Query: 566 LTQVSELPSSVI--HKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLT 623 +V E+P + K + + +K + P P K K+P +P K Sbjct: 9947 PVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPV-LIPKK--------- 9996 Query: 624 AKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPK 683 KP PA + P+ +K + + P + K+ + K V ++K +P+P PK Sbjct: 9997 EKPPPAKV-PEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKK----VPVPAPK 10051 Query: 684 KTRA 687 K A Sbjct: 10052 KVEA 10055 Score = 35.4 bits (80), Expect = 0.21 Identities = 65/293 (22%), Positives = 102/293 (34%), Gaps = 39/293 (13%) Query: 432 IRRKIVKPKHHVLMSRKESWKVK-SEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELA 490 + +KI + K V + +KE+ K E+PK + VL + + + +LE + +A Sbjct: 10295 VSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVA 10354 Query: 491 EDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSP 550 +E E+ +E P F + H E L R+ Sbjct: 10355 FRQEVVVKERLELEVVEAEVE-EIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQH--RVEE 10411 Query: 551 ERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEK--DQKKPPTAPREVKGTRRKLPT 608 E ++ + E +V E+ EK KKPPT K RK P Sbjct: 10412 EHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPT-----KVVPRKEPP 10466 Query: 609 AFLPS--KYHGYEELLTAKPDPAF--------IEPKGIQKNAQALQQMLKHPLLCHSSKP 658 A +P K EE + +P + PK + + K P + P Sbjct: 10467 AKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKP---EAPPP 10523 Query: 659 KLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAV 711 K+ K V ++K +P+PPPKK P + E P AV Sbjct: 10524 KVPEAPKEVVPEKK----VPVPPPKKPEV-----------PPTKVPEVPKAAV 10561 Score = 31.6 bits (70), Expect = 3.0 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 15/119 (12%) Query: 568 QVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTR-RKLPTAFLPSKYHGYEELLTAKP 626 +V E P V+ EK PP EV T+ ++P A +P K E + KP Sbjct: 10524 KVPEAPKEVV-------PEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKK--VPEAIPPKP 10574 Query: 627 DPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQR-IPIPPPKK 684 + E K +++ P KP++ ++ P KE ++ +P+PPPKK Sbjct: 10575 ESPPPEVPEAPKEVVPEKKVPAAP----PKKPEVTPVKVPEAPKEVVPEKKVPVPPPKK 10629 Score = 30.8 bits (68), Expect = 5.1 Identities = 56/292 (19%), Positives = 106/292 (36%), Gaps = 46/292 (15%) Query: 454 KSEIP--KVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLE 511 K E+P KVP+ P V + P K PE+ E + ++E E P E +E Sbjct: 10629 KPEVPPTKVPEVPKVAVPEKKVPEAIPPK----PESPPPEVFEEPEEVALE-EPPAEVVE 10683 Query: 512 GHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSPERPSDEDSKSTESIFL----- 566 P+ V +PP + ++ + PE P + + + + Sbjct: 10684 EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPE 10743 Query: 567 ---TQVSELPSSVIHKDDLELKEKDQKKPPTAPR-EVKGTRRKLPTAFLPSKYHG----- 617 +V E+P V+ + + + +K + P P K + P +P + Sbjct: 10744 APPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEV 10803 Query: 618 YEE-----------------LLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKL 660 YEE + A+ + + P + + + + K P++ KP+ Sbjct: 10804 YEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVI---KKPEA 10860 Query: 661 DTLQKP----YVHKEKRAQRIPIPPPKKTRAQLLDDIF-IRLRDPRNITEAP 707 ++P + K K R P PPP + + + IF ++ + + E P Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKP 10912 >gi|20143971 toll-like receptor 6 [Homo sapiens] Length = 796 Score = 46.6 bits (109), Expect = 9e-05 Identities = 57/216 (26%), Positives = 91/216 (42%), Gaps = 46/216 (21%) Query: 86 HILDQAFLLKH---HCVRKPSDLCTINAKENDFKHF------HSVIYINASENLLPLEAF 136 HI +Q FL + V ++ + + F H + ++N ++N+ F Sbjct: 311 HITNQVFLFSQTALYTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFLNFTQNVFTDSIF 370 Query: 137 H---TFPALKELDLAFNGIKTIYVKYG----DFKLLEFLDLSFNSLT----------VEA 179 T L+ L L NG+K ++ K G D LE LD+S+NSL VE+ Sbjct: 371 EKCSTLVKLETLILQKNGLKDLF-KVGLMTKDMPSLEILDVSWNSLESGRHKENCTWVES 429 Query: 180 ICDLGIL-------------PHLRVLLLTGNGLTSLPPNL----AVAEQEASVTSLTSKR 222 I L + P ++VL L N + S+P + A+ E + SLT Sbjct: 430 IVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLEALQELNVAFNSLTDLP 489 Query: 223 YILRFPALETLMLDDNRLSNPSC--FASLAGLRRLK 256 F +L L++D N +S+PS F S +R +K Sbjct: 490 GCGSFSSLSVLIIDHNSVSHPSADFFQSCQKMRSIK 525 Score = 35.4 bits (80), Expect = 0.21 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Query: 115 FKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYV--KYGDFKLLEFLDLSF 172 FK + Y++ S N L + H + + LDL+FN K + + ++G+ L FL LS Sbjct: 96 FKFNQDLEYLDLSHNQLQKISCHPIVSFRHLDLSFNDFKALPICKEFGNLSQLNFLGLSA 155 Query: 173 NSLTVEAICDLGILPHLRVLLL 194 L + + L HL +LL Sbjct: 156 MKLQKLDLLPIAHL-HLSYILL 176 >gi|157694513 leucine-rich repeat-containing G protein-coupled receptor 4 [Homo sapiens] Length = 951 Score = 46.6 bits (109), Expect = 9e-05 Identities = 51/143 (35%), Positives = 64/143 (44%), Gaps = 25/143 (17%) Query: 131 LPLEAFHTFPALKELDLAFNGIKTIYVK-YGDFKLLEFLDLSFNSLTV---EAICDLGIL 186 LP +AF FP L+EL LA N + I+ K K L+ L L N L EAI L L Sbjct: 72 LPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSAL 131 Query: 187 PHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCF 246 LR L N +TS+P E S L R+ L LDDN L+ Sbjct: 132 QSLR---LDANHITSVP--------EDSFEGLVQLRH---------LWLDDNSLTEVPVH 171 Query: 247 ASLAGLRRLKKLSLDENRIIRIP 269 L+ L L+ L+L N+I IP Sbjct: 172 -PLSNLPTLQALTLALNKISSIP 193 Score = 33.1 bits (74), Expect = 1.0 Identities = 45/191 (23%), Positives = 74/191 (38%), Gaps = 42/191 (21%) Query: 94 LKHHCVRKPSDLCTINAKENDFKHFHSVI----------YINASENLLPLEAFHTFPALK 143 L HC +L T++ N+ F I + + S +++P AF P L+ Sbjct: 216 LSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLR 275 Query: 144 ELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILP------HLRVLLLTGN 197 + L N + + G+ DL +SL + + P HL L LTG Sbjct: 276 TIHLYDNPLSFV----GNSAFHNLSDL--HSLVIRGASMVQQFPNLTGTVHLESLTLTGT 329 Query: 198 GLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKK 257 ++S+P NL ++ L TL L N + + S G L++ Sbjct: 330 KISSIPNNLCQEQK-----------------MLRTLDLSYNNIRD---LPSFNGCHALEE 369 Query: 258 LSLDENRIIRI 268 +SL N+I +I Sbjct: 370 ISLQRNQIYQI 380 >gi|16751843 toll-like receptor 5 [Homo sapiens] Length = 858 Score = 45.8 bits (107), Expect = 2e-04 Identities = 70/275 (25%), Positives = 115/275 (41%), Gaps = 43/275 (15%) Query: 124 INASENLLP---LEAFHTFPALKELDLAFNGIKTIYVKYGDF-KLLEFLDLSFNSLTVEA 179 +N S NLL F+ P + +DL N I I + F + L+ LDL N+LT Sbjct: 341 LNLSYNLLGELYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTT-- 398 Query: 180 ICDLGILPHLRVLLLTGNGLTSLPPNLAVAE----QEASVTSLTSKRYILRFPALETLML 235 + +P + + L+GN L +LP A E + +L ++LR P L+ L+L Sbjct: 399 ---IHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQILIL 455 Query: 236 DDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQL-YDESVDWNGGRGSPHKEP 294 + NR S+ S + + L++L L EN +QL ++ + W+ G H + Sbjct: 456 NQNRFSSCSGDQTPSENPSLEQLFLGEN---------MLQLAWETELCWDVFEGLSHLQV 506 Query: 295 QFMLQSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEIL 354 ++ + L + + + +R V+ + LP EIL Sbjct: 507 LYLNHNYLNSLPPGVFSHLTALRGLSLNSNRLTVLSHN-------------DLPANLEIL 553 Query: 355 PVKSLKARNQTLAP---PFPELRYLSLAYNKIAKE 386 + +RNQ LAP F L L + +NK E Sbjct: 554 DI----SRNQLLAPNPDVFVSLSVLDITHNKFICE 584 >gi|34577083 ras suppressor protein 1 isoform 2 [Homo sapiens] Length = 224 Score = 45.8 bits (107), Expect = 2e-04 Identities = 41/157 (26%), Positives = 69/157 (43%), Gaps = 22/157 (14%) Query: 114 DFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFN 173 + K+ + + N LP + + LK L+L N + T+ +G LE LDL++N Sbjct: 8 ELKNLEVLNFFNNQIEELPTQ-ISSLQKLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYN 66 Query: 174 SLTVEAI-CDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALET 232 +L+ ++ + L LR L L+ N LPP++ + L+ Sbjct: 67 NLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG------------------KLTKLQI 108 Query: 233 LMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269 L L DN L S + L +LK+L + NR+ +P Sbjct: 109 LSLRDNDLI--SLPKEIGELTQLKELHIQGNRLTVLP 143 Score = 39.7 bits (91), Expect = 0.011 Identities = 30/84 (35%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 123 YINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICD 182 Y N SEN LP F+ L+ L L+ N + + G L+ L L N L + + Sbjct: 65 YNNLSENSLPGNFFY-LTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDL-ISLPKE 122 Query: 183 LGILPHLRVLLLTGNGLTSLPPNL 206 +G L L+ L + GN LT LPP L Sbjct: 123 IGELTQLKELHIQGNRLTVLPPEL 146 >gi|33285015 leucine rich repeat containing 28 [Homo sapiens] Length = 367 Score = 45.4 bits (106), Expect = 2e-04 Identities = 49/167 (29%), Positives = 74/167 (44%), Gaps = 14/167 (8%) Query: 111 KENDFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDL 170 K+ ++ + S LP P L EL L N I + G L+ LDL Sbjct: 36 KDEGLQYLERLYMKRNSLTSLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDL 95 Query: 171 SFNSLTVEAIC-DLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFP- 228 S N+L E +C ++G L LR L L N L LPP + ++ ++ T++ +L P Sbjct: 96 SDNAL--EIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNR--LLTLPE 151 Query: 229 ------ALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269 +L+ L +D NRL L L L +LS+ NR+ +P Sbjct: 152 RLHMCLSLQYLTVDRNRLWYVP--RHLCQLPSLNELSMAGNRLAFLP 196 >gi|4504379 leucine-rich repeat-containing G protein-coupled receptor 5 [Homo sapiens] Length = 907 Score = 45.1 bits (105), Expect = 3e-04 Identities = 36/112 (32%), Positives = 52/112 (46%), Gaps = 12/112 (10%) Query: 167 FLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRY--- 223 +LDLS N+++ L L L L L GN LT +P V L + + Sbjct: 70 YLDLSMNNISQLLPNPLPSLRFLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHV 129 Query: 224 ----ILRFPALETLMLDDNRLS--NPSCFASLAGLRRLKKLSLDENRIIRIP 269 + +L++L LD N +S PSCF +GL L+ L LD+N + IP Sbjct: 130 PTEALQNLRSLQSLRLDANHISYVPPSCF---SGLHSLRHLWLDDNALTEIP 178 >gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sapiens] Length = 516 Score = 45.1 bits (105), Expect = 3e-04 Identities = 46/133 (34%), Positives = 60/133 (45%), Gaps = 19/133 (14%) Query: 134 EAFHTFPALKELDLAFNGIKTIYVK-YGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVL 192 E F+ L+ L L N ++TI V+ + D + LEFLDLS N L A L LR L Sbjct: 151 ELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLREL 210 Query: 193 LLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGL 252 L N LT + N A + LR +L TL L N++SN +C Sbjct: 211 HLEHNQLTKI--NFA---------------HFLRLSSLHTLFLQWNKISNLTCGMEWT-W 252 Query: 253 RRLKKLSLDENRI 265 L+KL L N I Sbjct: 253 GTLEKLDLTGNEI 265 >gi|40217825 slit and trk like 6 [Homo sapiens] Length = 841 Score = 45.1 bits (105), Expect = 3e-04 Identities = 44/156 (28%), Positives = 66/156 (42%), Gaps = 22/156 (14%) Query: 113 NDFKHFHSVIYINAS-ENLLPLE--AFHTFPALKELDLAFNGIKTIYVK-YGDFKLLEFL 168 NDF + I I+ N+ +E AF+ LK+L + N ++ + + + LEFL Sbjct: 82 NDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILKEDTFHGLENLEFL 141 Query: 169 DLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFP 228 N +TV L L+VL+L N + SLPPN I RF Sbjct: 142 QADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPN------------------IFRFV 183 Query: 229 ALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENR 264 L L L N+L L + R+ L L++N+ Sbjct: 184 PLTHLDLRGNQLQTLPYVGFLEHIGRILDLQLEDNK 219 >gi|219521831 adhesion molecule with Ig-like domain 2 [Homo sapiens] Length = 522 Score = 44.7 bits (104), Expect = 3e-04 Identities = 47/153 (30%), Positives = 69/153 (45%), Gaps = 25/153 (16%) Query: 135 AFHTFPALKELDLAFNGIKTI-YVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLL 193 +F T P LK LDL+ N +KT+ + + K+LE L L N ++ G L L+ L Sbjct: 112 SFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLY 171 Query: 194 LTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLD--DNRL-SNPSCFASLA 250 L+GN LT P +L Y+ RF E + LD NR+ S P +L Sbjct: 172 LSGNFLTQFPMDL----------------YVGRFKLAELMFLDVSYNRIPSMPMHHINLV 215 Query: 251 GLRRLKKLSLDENRIIRIPYLQQVQLYDESVDW 283 ++L+ + L N P++ LY V W Sbjct: 216 PGKQLRGIYLHGN-----PFVCDCSLYSLLVFW 243 >gi|32469517 adhesion molecule with Ig-like domain 2 [Homo sapiens] Length = 522 Score = 44.7 bits (104), Expect = 3e-04 Identities = 47/153 (30%), Positives = 69/153 (45%), Gaps = 25/153 (16%) Query: 135 AFHTFPALKELDLAFNGIKTI-YVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLL 193 +F T P LK LDL+ N +KT+ + + K+LE L L N ++ G L L+ L Sbjct: 112 SFSTTPNLKCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLY 171 Query: 194 LTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLD--DNRL-SNPSCFASLA 250 L+GN LT P +L Y+ RF E + LD NR+ S P +L Sbjct: 172 LSGNFLTQFPMDL----------------YVGRFKLAELMFLDVSYNRIPSMPMHHINLV 215 Query: 251 GLRRLKKLSLDENRIIRIPYLQQVQLYDESVDW 283 ++L+ + L N P++ LY V W Sbjct: 216 PGKQLRGIYLHGN-----PFVCDCSLYSLLVFW 243 >gi|110825984 malignant fibrous histiocytoma amplified sequence 1 [Homo sapiens] Length = 1052 Score = 44.3 bits (103), Expect = 4e-04 Identities = 46/138 (33%), Positives = 70/138 (50%), Gaps = 16/138 (11%) Query: 141 ALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSL-TVEA-ICDLGILPHLRVLLLTGNG 198 AL+ELD++ N ++ + + L+ L LS L T+ A C+L L L+L NG Sbjct: 205 ALEELDVSSNRLRGLPEDISALRALKILWLSGAELGTLPAGFCELA---SLESLMLDNNG 261 Query: 199 LTSLPPNLAVAEQEASVTSLTSKRY------ILRFPALETLMLDDNRLSN-PSCFASLAG 251 L +LP + Q + +L+S + +L LE L L N+L++ PS ++G Sbjct: 262 LQALPAQFSCL-QRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQLTSVPSL---ISG 317 Query: 252 LRRLKKLSLDENRIIRIP 269 L RL L LD NRI +P Sbjct: 318 LGRLLTLWLDNNRIRYLP 335 Score = 43.1 bits (100), Expect = 0.001 Identities = 50/160 (31%), Positives = 70/160 (43%), Gaps = 13/160 (8%) Query: 119 HSVIYINASENLLPLEAFHTFPALKEL---DLAFNGIKTIYVKYGDFKLLEFLDLSFNSL 175 H + ++ S N L AL+EL +L+ N + + + G LE LD+SFN L Sbjct: 111 HHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNRL 170 Query: 176 TVEAICDLGILPHLRVLLLTGNGLTSLPPNL--AVAEQEASVTSLTSK---RYILRFPAL 230 L L LR L + N LT+ P L VA +E V+S + I AL Sbjct: 171 -AHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLPEDISALRAL 229 Query: 231 ETLMLDDNRLSN-PSCFASLAGLRRLKKLSLDENRIIRIP 269 + L L L P+ F LA L+ L LD N + +P Sbjct: 230 KILWLSGAELGTLPAGFCELAS---LESLMLDNNGLQALP 266 Score = 34.3 bits (77), Expect = 0.46 Identities = 37/113 (32%), Positives = 52/113 (46%), Gaps = 11/113 (9%) Query: 165 LEFLDLSFNSLTVEAICDLG-ILPHLRVLLLTGNGLTSLPPNLA-----VAEQEASVTSL 218 +E L+L N L E LG L LRVL+L N LPP +A + E + S L Sbjct: 65 IEALNLGNNGLE-EVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHNRL 123 Query: 219 TS--KRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269 T+ + L L L N+L P+ A L L L++L + NR+ +P Sbjct: 124 TALGAEVVSALRELRKLNLSHNQL--PALPAQLGALAHLEELDVSFNRLAHLP 174 Score = 30.8 bits (68), Expect = 5.1 Identities = 36/134 (26%), Positives = 53/134 (39%), Gaps = 9/134 (6%) Query: 186 LPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPA-------LETLMLDDN 238 L + L L NGL +P L A V L R+ PA L L + N Sbjct: 62 LGDIEALNLGNNGLEEVPEGLGSALGSLRVLVLRRNRFARLPPAVAELGHHLTELDVSHN 121 Query: 239 RLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFML 298 RL+ ++ LR L+KL+L N++ +P + E +D + R H Sbjct: 122 RLTALGA-EVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNR-LAHLPDSLSC 179 Query: 299 QSKPRMLEDSDEQL 312 S+ R L+ QL Sbjct: 180 LSRLRTLDVDHNQL 193 >gi|7662320 leucine-rich repeats and immunoglobulin-like domains 2 [Homo sapiens] Length = 1065 Score = 44.3 bits (103), Expect = 4e-04 Identities = 39/159 (24%), Positives = 74/159 (46%), Gaps = 11/159 (6%) Query: 120 SVIYINASENLLP---LEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSL- 175 ++ ++ N++P +A +PAL+ LDL+ N I I L++L+LS N + Sbjct: 121 NITLLSLVHNIIPEINAQALQFYPALESLDLSSNIISEIKTSSFPRMQLKYLNLSNNRIT 180 Query: 176 TVEAICDLGILPHLRVLLLTGNGLTSLP------PNLAVAEQEASVTSLTSKRYILRFPA 229 T+EA C + L V+ L N ++ +P P+L E + + + + Sbjct: 181 TLEAGCFDNLSSSLLVVKLNRNRMSMIPPKIFKLPHLQFLELKRNRIKIVEGLTFQGLDS 240 Query: 230 LETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRI 268 L +L + N +S + GL +++L L+ N + R+ Sbjct: 241 LRSLKMQRNGISKLK-DGAFFGLNNMEELELEHNNLTRV 278 >gi|42544233 leucine rich repeat neuronal 2 [Homo sapiens] Length = 713 Score = 43.9 bits (102), Expect = 6e-04 Identities = 68/278 (24%), Positives = 109/278 (39%), Gaps = 63/278 (22%) Query: 131 LPLEAFHTFPALKELDLAFNGIKTIYVKYGDF-KLLEFLDLSFNSLTVEAICD---LGIL 186 +P A P LK LDL N ++ V GDF +L +L N++ D L L Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQR--VGPGDFANMLHLKELGLNNMEELVSIDKFALVNL 309 Query: 187 PHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCF 246 P L L +T N P L S R P +ETLML++N LS Sbjct: 310 PELTKLDITNN------PRL----------SFIHPRAFHHLPQMETLMLNNNALS----- 348 Query: 247 ASLAGLRRLKKLSLDENRIIRIPYLQQVQLY------DESVDWNGGRGSPHK--EPQFML 298 +L + + +P LQ+V L+ D + W G+ + EPQ L Sbjct: 349 ------------ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTL 396 Query: 299 QSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKS 358 ++P L ++L +P ++ D + S S PP ++ +S Sbjct: 397 CAEPPDL----QRLPVREVPFREMTDHCLPLISPR------------SFPPSLQVASGES 440 Query: 359 LKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFP 396 + + LA P PE+ +++ A ++ A ++P Sbjct: 441 MVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYP 478 Score = 34.7 bits (78), Expect = 0.36 Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 22/165 (13%) Query: 109 NAKENDFKHFHSVIYINASENLLPLEAFHTFPALKEL-DLAFNGIKTIYVKYGDFK-LLE 166 +A++ DF ++ ++ EN L H+F L L +L N + + F L Sbjct: 107 DARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSN 166 Query: 167 FLDLSFNSLTVEAICD--LGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYI 224 L L NS + AI +LP+L +L++ GN + ++ + + L + Sbjct: 167 LLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAI--------LDMNFRPLAN---- 214 Query: 225 LRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269 L +L+L L S +A L GL+ L+ LS +N++ R+P Sbjct: 215 -----LRSLVLAGMNLREISDYA-LEGLQSLESLSFYDNQLARVP 253 Score = 32.3 bits (72), Expect = 1.8 Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 24/122 (19%) Query: 168 LDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRF 227 LDLS NS + CD LP L L L N LT L ++ S L S Sbjct: 98 LDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRL--------EDHSFAGLAS------- 142 Query: 228 PALETLMLDDNRLSN--PSCFASLAGLRRLKKLS-----LDENRIIRIPYLQQVQLYDES 280 L+ L L+ N+L P F+ L+ L RL S +D +P L+ + + Sbjct: 143 --LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNK 200 Query: 281 VD 282 VD Sbjct: 201 VD 202 >gi|42544231 leucine rich repeat neuronal 2 [Homo sapiens] Length = 713 Score = 43.9 bits (102), Expect = 6e-04 Identities = 68/278 (24%), Positives = 109/278 (39%), Gaps = 63/278 (22%) Query: 131 LPLEAFHTFPALKELDLAFNGIKTIYVKYGDF-KLLEFLDLSFNSLTVEAICD---LGIL 186 +P A P LK LDL N ++ V GDF +L +L N++ D L L Sbjct: 252 VPRRALEQVPGLKFLDLNKNPLQR--VGPGDFANMLHLKELGLNNMEELVSIDKFALVNL 309 Query: 187 PHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCF 246 P L L +T N P L S R P +ETLML++N LS Sbjct: 310 PELTKLDITNN------PRL----------SFIHPRAFHHLPQMETLMLNNNALS----- 348 Query: 247 ASLAGLRRLKKLSLDENRIIRIPYLQQVQLY------DESVDWNGGRGSPHK--EPQFML 298 +L + + +P LQ+V L+ D + W G+ + EPQ L Sbjct: 349 ------------ALHQQTVESLPNLQEVGLHGNPIRCDCVIRWANATGTRVRFIEPQSTL 396 Query: 299 QSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKS 358 ++P L ++L +P ++ D + S S PP ++ +S Sbjct: 397 CAEPPDL----QRLPVREVPFREMTDHCLPLISPR------------SFPPSLQVASGES 440 Query: 359 LKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFP 396 + + LA P PE+ +++ A ++ A ++P Sbjct: 441 MVLHCRALAEPEPEIYWVTPAGLRLTPAHAGRRYRVYP 478 Score = 34.7 bits (78), Expect = 0.36 Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 22/165 (13%) Query: 109 NAKENDFKHFHSVIYINASENLLPLEAFHTFPALKEL-DLAFNGIKTIYVKYGDFK-LLE 166 +A++ DF ++ ++ EN L H+F L L +L N + + F L Sbjct: 107 DARDCDFHALPQLLSLHLEENQLTRLEDHSFAGLASLQELYLNHNQLYRIAPRAFSGLSN 166 Query: 167 FLDLSFNSLTVEAICD--LGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYI 224 L L NS + AI +LP+L +L++ GN + ++ + + L + Sbjct: 167 LLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNKVDAI--------LDMNFRPLAN---- 214 Query: 225 LRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269 L +L+L L S +A L GL+ L+ LS +N++ R+P Sbjct: 215 -----LRSLVLAGMNLREISDYA-LEGLQSLESLSFYDNQLARVP 253 Score = 32.3 bits (72), Expect = 1.8 Identities = 37/122 (30%), Positives = 50/122 (40%), Gaps = 24/122 (19%) Query: 168 LDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRF 227 LDLS NS + CD LP L L L N LT L ++ S L S Sbjct: 98 LDLSQNSFSDARDCDFHALPQLLSLHLEENQLTRL--------EDHSFAGLAS------- 142 Query: 228 PALETLMLDDNRLSN--PSCFASLAGLRRLKKLS-----LDENRIIRIPYLQQVQLYDES 280 L+ L L+ N+L P F+ L+ L RL S +D +P L+ + + Sbjct: 143 --LQELYLNHNQLYRIAPRAFSGLSNLLRLHLNSNLLRAIDSRWFEMLPNLEILMIGGNK 200 Query: 281 VD 282 VD Sbjct: 201 VD 202 >gi|38202222 fibronectin leucine rich transmembrane protein 3 precursor [Homo sapiens] Length = 649 Score = 43.5 bits (101), Expect = 8e-04 Identities = 43/125 (34%), Positives = 58/125 (46%), Gaps = 24/125 (19%) Query: 142 LKELDLAFNGIKTI-YVKYGDFKLLEFLDLSFNSLTVEAICDLGILP--HLRVLLLTGNG 198 +KEL L N I+TI Y LE L L NS++ +I + +LR+L L+ N Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165 Query: 199 LTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKL 258 L+++P L +E L LDDNR+S S SL GL LK+L Sbjct: 166 LSTIPWGLP--------------------RTIEELRLDDNRISTISS-PSLQGLTSLKRL 204 Query: 259 SLDEN 263 LD N Sbjct: 205 VLDGN 209 >gi|7019383 fibronectin leucine rich transmembrane protein 3 precursor [Homo sapiens] Length = 649 Score = 43.5 bits (101), Expect = 8e-04 Identities = 43/125 (34%), Positives = 58/125 (46%), Gaps = 24/125 (19%) Query: 142 LKELDLAFNGIKTI-YVKYGDFKLLEFLDLSFNSLTVEAICDLGILP--HLRVLLLTGNG 198 +KEL L N I+TI Y LE L L NS++ +I + +LR+L L+ N Sbjct: 106 VKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNH 165 Query: 199 LTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKL 258 L+++P L +E L LDDNR+S S SL GL LK+L Sbjct: 166 LSTIPWGLP--------------------RTIEELRLDDNRISTISS-PSLQGLTSLKRL 204 Query: 259 SLDEN 263 LD N Sbjct: 205 VLDGN 209 >gi|62241040 leucine rich repeat containing 8 family, member A [Homo sapiens] Length = 810 Score = 43.1 bits (100), Expect = 0.001 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 12/121 (9%) Query: 97 HCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPA-----------LKEL 145 H + +L I+ K+N+ K +I L L+ ++ A L+ L Sbjct: 608 HSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERL 667 Query: 146 DLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPN 205 L N I+ I + + L +LDLS N+LT D+G+L +L+ L +T N + +LPP Sbjct: 668 YLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLP-ADIGLLQNLQNLAITANRIETLPPE 726 Query: 206 L 206 L Sbjct: 727 L 727 >gi|187829877 leucine rich repeat containing 8 family, member A [Homo sapiens] Length = 810 Score = 43.1 bits (100), Expect = 0.001 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 12/121 (9%) Query: 97 HCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPA-----------LKEL 145 H + +L I+ K+N+ K +I L L+ ++ A L+ L Sbjct: 608 HSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERL 667 Query: 146 DLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPN 205 L N I+ I + + L +LDLS N+LT D+G+L +L+ L +T N + +LPP Sbjct: 668 YLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLP-ADIGLLQNLQNLAITANRIETLPPE 726 Query: 206 L 206 L Sbjct: 727 L 727 >gi|187829871 leucine rich repeat containing 8 family, member A [Homo sapiens] Length = 810 Score = 43.1 bits (100), Expect = 0.001 Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 12/121 (9%) Query: 97 HCVRKPSDLCTINAKENDFKHFHSVIYINASENLLPLEAFHTFPA-----------LKEL 145 H + +L I+ K+N+ K +I L L+ ++ A L+ L Sbjct: 608 HSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYNHIAYIPIQIGNLTNLERL 667 Query: 146 DLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPN 205 L N I+ I + + L +LDLS N+LT D+G+L +L+ L +T N + +LPP Sbjct: 668 YLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLP-ADIGLLQNLQNLAITANRIETLPPE 726 Query: 206 L 206 L Sbjct: 727 L 727 >gi|61966761 leucine rich repeat containing 26 [Homo sapiens] Length = 334 Score = 42.7 bits (99), Expect = 0.001 Identities = 39/112 (34%), Positives = 52/112 (46%), Gaps = 18/112 (16%) Query: 131 LPLEAFHTFPALKELDLAFNGIKTIYVK-YGDFKLLEFLDLSFNSLTVEAICDLGILPHL 189 LP AF AL+ LDL NG+ +++V+ + L+ LDLS N L A L L Sbjct: 86 LPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLSANQLEALAPGTFAPLRAL 145 Query: 190 RVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLS 241 R L L GN L L P A++ +L P L +L L DN L+ Sbjct: 146 RNLSLAGNRLARLEP--------AALGAL---------PLLRSLSLQDNELA 180 Score = 30.8 bits (68), Expect = 5.1 Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 20/115 (17%) Query: 184 GILPHLRVLLLTGNGLTSLPPNL-----AVAEQEASVTSLTS--KRYILRFPALETLMLD 236 G+ LR LLL N + +LPP A+ + L S R AL+ L L Sbjct: 68 GLSLRLRALLLDHNRVRALPPGAFAGAGALQRLDLRENGLHSVHVRAFWGLGALQLLDLS 127 Query: 237 DNRLS--NPSCFASLAGLRRLKKLSLDENRIIR--------IPYLQQVQLYDESV 281 N+L P FA LR L+ LSL NR+ R +P L+ + L D + Sbjct: 128 ANQLEALAPGTFAP---LRALRNLSLAGNRLARLEPAALGALPLLRSLSLQDNEL 179 >gi|45827729 scribble isoform b [Homo sapiens] Length = 1630 Score = 42.7 bits (99), Expect = 0.001 Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 10/160 (6%) Query: 117 HFHSVIYINASENLLPLEAFHTFPALKELDLA-FNGIKTIYVKYGDFKLLEFLDLSFNSL 175 +F ++ ++ S N +P E + K L++A F+G + G +L L+ N + Sbjct: 80 NFMQLVELDVSRNDIP-EIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDV 138 Query: 176 TVEAIC-DLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYIL-----RFPA 229 +++A+ D+G L +L L L N L SLP +L+ + + + +L P Sbjct: 139 SLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPN 198 Query: 230 LETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269 L L LD N+LS + L LRRL L + ENR+ +P Sbjct: 199 LRELWLDRNQLS--ALPPELGNLRRLVCLDVSENRLEELP 236 Score = 40.8 bits (94), Expect = 0.005 Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 14/135 (10%) Query: 142 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICD-LGILPHLRVLLLTGNGLT 200 L L+L N +K++ LE LDL N L E + D LG LP+LR L L N L+ Sbjct: 153 LVTLELRENLLKSLPASLSFLVKLEQLDLGGNDL--EVLPDTLGALPNLRELWLDRNQLS 210 Query: 201 SLPPNLAVAEQEASVTSLTSKRYILRFPA-------LETLMLDDNRLSNPSCFASLAGLR 253 +LPP L + + S+ + PA L L+L N L + L+ Sbjct: 211 ALPPELGNLRRLVCLD--VSENRLEELPAELGGLVLLTDLLLSQNLLRRLP--DGIGQLK 266 Query: 254 RLKKLSLDENRIIRI 268 +L L +D+NR+ + Sbjct: 267 QLSILKVDQNRLCEV 281 Score = 37.7 bits (86), Expect = 0.042 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 10/136 (7%) Query: 140 PALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGL 199 P L+EL L N + + + G+ + L LD+S N L E +LG L L LLL+ N L Sbjct: 197 PNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLE-ELPAELGGLVLLTDLLLSQNLL 255 Query: 200 TSLPPNLAVAEQEASVTSLTSKRYILRFPA------LETLMLDDNRLSNPSCFASLAGLR 253 LP + +Q S+ + R A L L+L +N L + SL L Sbjct: 256 RRLPDGIGQLKQ-LSILKVDQNRLCEVTEAIGDCENLSELILTENLLM--ALPRSLGKLT 312 Query: 254 RLKKLSLDENRIIRIP 269 +L L++D N + +P Sbjct: 313 KLTNLNVDRNHLEALP 328 >gi|45827731 scribble isoform a [Homo sapiens] Length = 1655 Score = 42.7 bits (99), Expect = 0.001 Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 10/160 (6%) Query: 117 HFHSVIYINASENLLPLEAFHTFPALKELDLA-FNGIKTIYVKYGDFKLLEFLDLSFNSL 175 +F ++ ++ S N +P E + K L++A F+G + G +L L+ N + Sbjct: 80 NFMQLVELDVSRNDIP-EIPESIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDV 138 Query: 176 TVEAIC-DLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYIL-----RFPA 229 +++A+ D+G L +L L L N L SLP +L+ + + + +L P Sbjct: 139 SLQALPGDVGNLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPN 198 Query: 230 LETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIP 269 L L LD N+LS + L LRRL L + ENR+ +P Sbjct: 199 LRELWLDRNQLS--ALPPELGNLRRLVCLDVSENRLEELP 236 Score = 40.8 bits (94), Expect = 0.005 Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 14/135 (10%) Query: 142 LKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICD-LGILPHLRVLLLTGNGLT 200 L L+L N +K++ LE LDL N L E + D LG LP+LR L L N L+ Sbjct: 153 LVTLELRENLLKSLPASLSFLVKLEQLDLGGNDL--EVLPDTLGALPNLRELWLDRNQLS 210 Query: 201 SLPPNLAVAEQEASVTSLTSKRYILRFPA-------LETLMLDDNRLSNPSCFASLAGLR 253 +LPP L + + S+ + PA L L+L N L + L+ Sbjct: 211 ALPPELGNLRRLVCLD--VSENRLEELPAELGGLVLLTDLLLSQNLLRRLP--DGIGQLK 266 Query: 254 RLKKLSLDENRIIRI 268 +L L +D+NR+ + Sbjct: 267 QLSILKVDQNRLCEV 281 Score = 37.7 bits (86), Expect = 0.042 Identities = 42/136 (30%), Positives = 63/136 (46%), Gaps = 10/136 (7%) Query: 140 PALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGL 199 P L+EL L N + + + G+ + L LD+S N L E +LG L L LLL+ N L Sbjct: 197 PNLRELWLDRNQLSALPPELGNLRRLVCLDVSENRLE-ELPAELGGLVLLTDLLLSQNLL 255 Query: 200 TSLPPNLAVAEQEASVTSLTSKRYILRFPA------LETLMLDDNRLSNPSCFASLAGLR 253 LP + +Q S+ + R A L L+L +N L + SL L Sbjct: 256 RRLPDGIGQLKQ-LSILKVDQNRLCEVTEAIGDCENLSELILTENLLM--ALPRSLGKLT 312 Query: 254 RLKKLSLDENRIIRIP 269 +L L++D N + +P Sbjct: 313 KLTNLNVDRNHLEALP 328 >gi|194394161 leucine rich repeat containing 57 [Homo sapiens] Length = 239 Score = 42.7 bits (99), Expect = 0.001 Identities = 51/161 (31%), Positives = 72/161 (44%), Gaps = 9/161 (5%) Query: 125 NASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLG 184 N E+L PL F LK L L N + + + + K LE L L+ N L E G Sbjct: 48 NKIESLPPL-LIGKFTLLKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLR-ELPSTFG 105 Query: 185 ILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFP----ALETLMLDDNRL 240 L L+ L L+GN L +LPP L + + V L SK I P L+ + L+ N+ Sbjct: 106 QLSALKTLSLSGNQLGALPPQLC-SLRHLDVMDL-SKNQIRSIPDSVGELQVIELNLNQN 163 Query: 241 SNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESV 281 ++ RLK L L+EN + + L Q L D + Sbjct: 164 QISQISVKISCCPRLKILRLEEN-CLELSMLPQSILSDSQI 203 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,025,104 Number of Sequences: 37866 Number of extensions: 1625832 Number of successful extensions: 5745 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 260 Number of HSP's that attempted gapping in prelim test: 5207 Number of HSP's gapped (non-prelim): 681 length of query: 792 length of database: 18,247,518 effective HSP length: 110 effective length of query: 682 effective length of database: 14,082,258 effective search space: 9604099956 effective search space used: 9604099956 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.