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Search of human proteins with 149944474
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|149944474 ATPase, class V, type 10B [Homo sapiens]
(1461 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 2954 0.0
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 1374 0.0
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 1267 0.0
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 432 e-121
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 424 e-118
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 410 e-114
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 406 e-113
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 406 e-113
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 387 e-107
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 369 e-102
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 369 e-102
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 361 2e-99
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 361 3e-99
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 361 3e-99
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 338 2e-92
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 273 7e-73
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 265 2e-70
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 229 1e-59
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 98 5e-20
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 98 5e-20
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 82 3e-15
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 82 3e-15
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 82 3e-15
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 82 3e-15
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 81 6e-15
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 81 6e-15
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens] 75 5e-13
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens] 75 5e-13
gi|66730421 ATPase type 13A5 [Homo sapiens] 75 6e-13
gi|66932949 ATPase type 13A4 [Homo sapiens] 70 1e-11
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 2954 bits (7658), Expect = 0.0
Identities = 1461/1461 (100%), Positives = 1461/1461 (100%)
Query: 1 MALSVDSSWHRWQWRVRDGFPHCPSETTPLLSPEKGRQSYNLTQQRVVFPNNSIFHQDWE 60
MALSVDSSWHRWQWRVRDGFPHCPSETTPLLSPEKGRQSYNLTQQRVVFPNNSIFHQDWE
Sbjct: 1 MALSVDSSWHRWQWRVRDGFPHCPSETTPLLSPEKGRQSYNLTQQRVVFPNNSIFHQDWE 60
Query: 61 EVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITML 120
EVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITML
Sbjct: 61 EVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITML 120
Query: 121 PLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKC 180
PLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKC
Sbjct: 121 PLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKC 180
Query: 181 NEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVC 240
NEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVC
Sbjct: 181 NEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVC 240
Query: 241 EKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNS 300
EKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNS
Sbjct: 241 EKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNS 300
Query: 301 GPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPS 360
GPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPS
Sbjct: 301 GPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPS 360
Query: 361 ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI 420
ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI
Sbjct: 361 ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI 420
Query: 421 AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQY 480
AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQY
Sbjct: 421 AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQY 480
Query: 481 QCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQPPVAFSSSI 540
QCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQPPVAFSSSI
Sbjct: 481 QCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQPPVAFSSSI 540
Query: 541 EKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSSIADFFLALTICNSVMVSTTTE 600
EKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSSIADFFLALTICNSVMVSTTTE
Sbjct: 541 EKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSSIADFFLALTICNSVMVSTTTE 600
Query: 601 PRQRVTIKPSSKALGTSLEKIQQLFQKLKLLSLSQSFSSTAPSDTDLGESLGANVATTDS 660
PRQRVTIKPSSKALGTSLEKIQQLFQKLKLLSLSQSFSSTAPSDTDLGESLGANVATTDS
Sbjct: 601 PRQRVTIKPSSKALGTSLEKIQQLFQKLKLLSLSQSFSSTAPSDTDLGESLGANVATTDS 660
Query: 661 DERDDASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFCYEAE 720
DERDDASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFCYEAE
Sbjct: 661 DERDDASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFCYEAE 720
Query: 721 SPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHP 780
SPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHP
Sbjct: 721 SPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHP 780
Query: 781 LTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIA 840
LTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIA
Sbjct: 781 LTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIA 840
Query: 841 KKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDT 900
KKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDT
Sbjct: 841 KKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDT 900
Query: 901 IATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEEL 960
IATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEEL
Sbjct: 901 IATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEEL 960
Query: 961 KQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQ 1020
KQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQ
Sbjct: 961 KQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQ 1020
Query: 1021 YCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQA 1080
YCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQA
Sbjct: 1021 YCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQA 1080
Query: 1081 VMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSST 1140
VMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSST
Sbjct: 1081 VMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSST 1140
Query: 1141 MIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMV 1200
MIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMV
Sbjct: 1141 MIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMV 1200
Query: 1201 DAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLG 1260
DAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLG
Sbjct: 1201 DAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLG 1260
Query: 1261 SFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQ 1320
SFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQ
Sbjct: 1261 SFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQ 1320
Query: 1321 GTCGKSLISKAQKIDKLPPDKRNLEIQSWRSRQRPAPVPEVARPTHHPVSSITGQDFSAS 1380
GTCGKSLISKAQKIDKLPPDKRNLEIQSWRSRQRPAPVPEVARPTHHPVSSITGQDFSAS
Sbjct: 1321 GTCGKSLISKAQKIDKLPPDKRNLEIQSWRSRQRPAPVPEVARPTHHPVSSITGQDFSAS 1380
Query: 1381 TPKSSNPPKRKHVEESVLHEQRCGTECMRDDSCSGDSSAQLSSGEHLLGPNRIMAYSRGQ 1440
TPKSSNPPKRKHVEESVLHEQRCGTECMRDDSCSGDSSAQLSSGEHLLGPNRIMAYSRGQ
Sbjct: 1381 TPKSSNPPKRKHVEESVLHEQRCGTECMRDDSCSGDSSAQLSSGEHLLGPNRIMAYSRGQ 1440
Query: 1441 TDMCRCSKRSSHRRSQSSLTI 1461
TDMCRCSKRSSHRRSQSSLTI
Sbjct: 1441 TDMCRCSKRSSHRRSQSSLTI 1461
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 1374 bits (3556), Expect = 0.0
Identities = 716/1363 (52%), Positives = 945/1363 (69%), Gaps = 39/1363 (2%)
Query: 9 WHRWQWR------VRDGFPHCPSETTPLLSPEKGRQSYNLT-QQRVVFPNNSIFHQDWEE 61
W R+ WR RD + ++ L K Q+ L+ + R+V P+ F ++E+
Sbjct: 7 WARYHWRRLIRGATRDDDSGPYNYSSLLACGRKSSQTPKLSGRHRIVVPHIQPFKDEYEK 66
Query: 62 VSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLP 121
S Y NR TTKYTL F+PRNLFEQFHR ANLYFLFLV+LNW+P +E F +EITMLP
Sbjct: 67 FSGAYVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLP 126
Query: 122 LAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCN 181
L +VL +I IKDG+ED+++++ DK IN ++Y RKE+ Y+ +CWKDV VGDFI++ CN
Sbjct: 127 LVVVLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCN 186
Query: 182 EIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVCE 241
E++PAD++LLFS+DP+GICH+ET+ LDGE+NLKQR VV+G+++Q+ + +PE F + I CE
Sbjct: 187 EVIPADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECE 246
Query: 242 KPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSG 301
PNN L++F+G++EH ++ R G E+LLLRGCTIRNTE VGIV+YAGHETKAMLNNSG
Sbjct: 247 SPNNDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSG 306
Query: 302 PRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSA 361
PRYKRSK+ERR N D+ +C+ +L++MCL GAVGH IW +E+ F+VP+ +G +
Sbjct: 307 PRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEPDGHIISPL 366
Query: 362 LGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIA 421
L GFYMF TMIILLQVLIPISLYVSIE+VKLGQ++F+ +D+D Y+E+ D +QCRALNIA
Sbjct: 367 LAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIA 426
Query: 422 EDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEW--TQ 479
EDLGQIQY+FSDKTGTLTENKMVFRRC++ G +Y H+ENA+RLE+ +E S+ E++ T
Sbjct: 427 EDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFIDTV 486
Query: 480 YQCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQP---PVAF 536
LS A+ + P+ G PL S + G G S P AF
Sbjct: 487 SGSLSNMAK-PRAPSCRTVHNG--PLGNKPSNH--LAGSSFTLGSGEGASEVPHSRQAAF 541
Query: 537 SSSIEKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSSIADFFLALTICNSVMVS 596
SS IE DV PD LL K L D + T I DFF+AL ICN+V+VS
Sbjct: 542 SSPIETDVVPDTRLLDKFSQITPRLFMPLDETIQNPPMETL-YIIDFFIALAICNTVVVS 600
Query: 597 TTTEPRQRVTIKPSSKALG-TSLEKIQQLFQKLKL-------LSLSQSFSSTAPSDTDLG 648
+PRQ++ PS L SLE+I+ LFQ+ + L+ + SS P+
Sbjct: 601 APNQPRQKIR-HPSLGGLPIKSLEEIKSLFQRWSVRRSSSPSLNSGKEPSSGVPNAFVSR 659
Query: 649 ESLGANVATTDSDERDDASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPAT 708
L + + E + + VC + S+ + + +G +A P
Sbjct: 660 LPLFSRMKPASPVEEEVSQVCESPQCSSS----SACCTETEKQHGDAGLLNGKAESLPGQ 715
Query: 709 DLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDS 768
LA CYEAESPDEAALV+AA AY TL SRTPEQV V LTF LL L FDS
Sbjct: 716 PLA-CNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLTFQLLHILPFDS 774
Query: 769 VRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPD-INMEKKLRKIRARTQKHLD 827
VRKRMSVVVRHPL+ ++VVYTKGADSVIM+LL PD ++EK+ +R +TQKHLD
Sbjct: 775 VRKRMSVVVRHPLSNQVVVYTKGADSVIMELLS--VASPDGASLEKQQMIVREKTQKHLD 832
Query: 828 LYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGAT 887
YA+ GLRTLCIAKKV+S+ ++ W AE S+DNR+ELL+E+A LEN+LTLLGAT
Sbjct: 833 DYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGAT 892
Query: 888 GIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQE 947
GIEDRLQEGVP++I L +AGI++W+LTGDKQETAVNIA++C+LL D ++ +NT++++
Sbjct: 893 GIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQSKD 952
Query: 948 TCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIF 1007
C +++ L+EL++ + L L P + AGL+I GKTL
Sbjct: 953 ACGMLMSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSG----LRAGLIITGKTLEFAL 1008
Query: 1008 QGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAAD 1067
Q L+K+FLELT +C++V+CCR+TPLQKS +VKLVR L+VMTL+IGDGANDVSMIQ AD
Sbjct: 1009 QESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLAIGDGANDVSMIQVAD 1068
Query: 1068 IGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLL 1127
IGIG+SGQEGMQAVM+SDFA+++FKHL KLLLVHGHWCY+RL+ M++Y+ YKNV YVNLL
Sbjct: 1069 IGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNMILYFFYKNVAYVNLL 1128
Query: 1128 FWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNS 1187
FWYQFFCGFS ++M DYW +IFFNL FTS PP+++GVL+KD+SAETL+ LPELY+SGQ S
Sbjct: 1129 FWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAETLMQLPELYRSGQKS 1188
Query: 1188 ECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEM 1247
E Y TFWI+++DAFYQSL+CFF+PY Y+GSD D+F FG P+NT +L +LLH +E
Sbjct: 1189 EAYLPHTFWITLLDAFYQSLVCFFVPYFTYQGSDTDIFAFGNPLNTAALFIVLLHLVIES 1248
Query: 1248 KTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLVCFLTPV 1307
K+ T H +V++GS L YFL ++++ A CV CN P+NPYW+M+ + +P FYLVC LT
Sbjct: 1249 KSLTWIHLLVIIGSILSYFLFAIVFGAMCVTCNPPSNPYWIMQEHMLDPVFYLVCILTTS 1308
Query: 1308 VALLPRYFFLSLQGTCGKSLISKAQKIDKLPPDKRNLEIQSWR 1350
+ALLPR+ + LQG+ S I +A+ D+L P++R ++ WR
Sbjct: 1309 IALLPRFVYRVLQGSLFPSPILRAKHFDRLTPEERTKALKKWR 1351
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 1267 bits (3279), Expect = 0.0
Identities = 686/1352 (50%), Positives = 900/1352 (66%), Gaps = 59/1352 (4%)
Query: 69 NRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFV 128
NR TTKYTL +FLP+NLFEQFHR AN+YF+F+ +LN++P++ F + + P+ +L +
Sbjct: 62 NRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAI 121
Query: 129 IMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADI 188
+D ED+ RHR D IN ++ R+E+ YV + WK++ VGDF++++CNEI PADI
Sbjct: 122 TAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADI 181
Query: 189 LLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVCEKPNNHLN 248
LLL SSDP+G+CH+ETA+LDGETNLK+R VV+GFS+ +F P F + I CEKPNN L+
Sbjct: 182 LLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLS 241
Query: 249 KFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSK 308
+F+G + H + + G E+LLLRGCT+RNT+ VGIVIYAGHETKA+LNNSGPRYKRSK
Sbjct: 242 RFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSK 301
Query: 309 IERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPP-FDVPDANGSFLPSALGGFYM 367
+ER+MN D+ +C+ +L+ M L AVGH +W ++E F VP ++GS L Y
Sbjct: 302 LERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYS 361
Query: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
FLTMII+LQVLIPISLYVSIE+VK QV+F++ D+ LYDEETD +QCRALNI EDLGQI
Sbjct: 362 FLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQI 421
Query: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLSFSA 487
QYIFSDKTGTLTENKMVFRRCT+ G EYSH NA+RL +E DS+ EE + S S
Sbjct: 422 QYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVP-RGGSVSQ 480
Query: 488 RWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQ---PPVAFSSSIEKDV 544
R ++ S + + + R+QS + H R S + + AFSS +EKD+
Sbjct: 481 R-----GSIGSHQSVRVVHRTQSTK----SHRRTGSRAEAKRASMLSKHTAFSSPMEKDI 531
Query: 545 TPDKNLLTKVRDAALWLETLSDSRPAKASLSTT-SSIADFFLALTICNSVMVSTTTEPRQ 603
TPD LL KV + L A LS S + DFF+ALTICN+V+V++ +PR
Sbjct: 532 TPDPKLLEKVSECDKSLAVARHQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRT 591
Query: 604 RVTIKPSSKALGTSLEKIQQLFQKLKLLSLSQSFSSTAPSDTDLGESLGANVATTDSDE- 662
+V ++ K+ ++E + F L S S S A + + LG++ +T S +
Sbjct: 592 KVRVRFELKSPVKTIEDFLRRFTPSCLTSGCSSIGSLAANKSS--HKLGSSFPSTPSSDG 649
Query: 663 ---RDDASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFCYEA 719
R + + + GY S Q D A E + E YEA
Sbjct: 650 MLLRLEERLGQPTSAIASNGYSS----QAD----------NWASELAQEQESERELRYEA 695
Query: 720 ESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVVVRH 779
ESPDEAALV+AA AY+ LV R +QV+V LP LTF LL TLGFDSVRKRMSVV+RH
Sbjct: 696 ESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLGFDSVRKRMSVVIRH 755
Query: 780 PLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCI 839
PLT EI VYTKGADSV+MDLL+ + V +K KIR++TQ +L++YA +GLRTLCI
Sbjct: 756 PLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQK--KIRSKTQNYLNVYAAEGLRTLCI 813
Query: 840 AKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPD 899
AK+V+S+E++ W EAE+SL+N +ELL ++A LE L LLGATGIEDRLQ+GVP+
Sbjct: 814 AKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPE 873
Query: 900 TIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEE 959
TI+ LR+AG+Q+WVLTGDKQETAVNIA++C+LL+ + V T+N +QE C ++L+ L
Sbjct: 874 TISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCY 933
Query: 960 LKQFRELQKPDRKLFG---FRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFL 1016
+ Q R LQ+ K G R S P TS A LVIDG++L + LE KFL
Sbjct: 934 V-QSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEKNLEDKFL 992
Query: 1017 ELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQE 1076
L + CRSVLCCRSTPLQKSM+VKLVR KL+ MTL+IGDGANDVSMIQ AD+G+GISGQE
Sbjct: 993 FLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQE 1052
Query: 1077 GMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGF 1136
GMQAVM+SDFA+ +F++L++LL++HGHWCYSRLA MV+Y+ YKN +V LLFW+QFFCGF
Sbjct: 1053 GMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGF 1112
Query: 1137 SSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFW 1196
S+STMID W +IFFNL F+SLPPLV GVLD+D+ A LL P+LYKSGQN E Y TFW
Sbjct: 1113 SASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFW 1172
Query: 1197 ISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGV 1256
+M DA +QSL+CF IPYLAY S++D+FT+GTPI TI+L T LLH +E KTWT + +
Sbjct: 1173 FNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWI 1232
Query: 1257 VLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFF 1316
S L++F V+L+YNA+C C P+NPYW M+ L +P FYL C +TPV ALLPR FF
Sbjct: 1233 TCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFF 1292
Query: 1317 LSLQGTCGKSLISKAQKIDKLPPDK----------------RNLEIQSWRSRQRPAPVPE 1360
SLQG + + A+++ + P + E S R+ + P+ +
Sbjct: 1293 RSLQGRVFPTQLQLARQLTRKSPRRCSAPKETFAQGRLPKDSGTEHSSGRTVKTSVPLSQ 1352
Query: 1361 VARPTHHPVSSITGQDFSASTPKSSNPPKRKH 1392
+ T PV S+ ++ S P R+H
Sbjct: 1353 PSWHTQQPVCSLEASGEPSTVDMSM--PVREH 1382
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 432 bits (1112), Expect = e-121
Identities = 243/622 (39%), Positives = 367/622 (59%), Gaps = 34/622 (5%)
Query: 714 EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773
E Y+A+SPDE ALV AA + F SRTP+ +TV GT +T+ LL L F+++RKRM
Sbjct: 519 ELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVH-EMGTAITYQLLAILDFNNIRKRM 577
Query: 774 SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833
SV+VR+P G+I +Y KGAD++++D L +++ T HL+ YA +G
Sbjct: 578 SVIVRNP-EGKIRLYCKGADTILLDRLHHST-----------QELLNTTMDHLNEYAGEG 625
Query: 834 LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893
LRTL +A K + EE + WA R +A + D+R++ L + +EN + LLGAT IED+L
Sbjct: 626 LRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKL 685
Query: 894 QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESIL 953
Q+GVP+TIA L A I++WVLTGDKQETAVNI +SC++L T I T + ++L
Sbjct: 686 QQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGH-----TVL 740
Query: 954 NCALEELKQFRELQKPDRKLFGF------RLPSKTPSITSEAVVPEAGLVIDGKTLNAIF 1007
EEL++ RE + G +L S + EAV E LVI+G +L
Sbjct: 741 EVR-EELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHAL 799
Query: 1008 QGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAAD 1067
+ +E +FLE C++V+CCR TPLQK+ +V+LV+ + +TL+IGDGANDVSMI+ A
Sbjct: 800 EADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAH 859
Query: 1068 IGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLL 1127
IG+GISGQEG+QAV++SD++ ++FK L++LLLVHG W Y R+ + + Y+ YKN + +
Sbjct: 860 IGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVH 919
Query: 1128 FWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNS 1187
FW+ FFCGFS+ T+ D + + +N+ +TSLP L GV D+D+ + + P+LY+ GQ +
Sbjct: 920 FWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLN 979
Query: 1188 ECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSD-------IDVFTFGTPINTISLTTIL 1240
+N F+I + Y S++ FFIPY + + D +F + T + +
Sbjct: 980 LLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVS 1039
Query: 1241 LHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQ--LSNPTF 1298
+ ++ WT + + GS +YF + ++ + P +V Q L+ PT
Sbjct: 1040 VQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTV 1099
Query: 1299 YLVCFLTPVVALLPRYFFLSLQ 1320
+L LT VV ++P F L+
Sbjct: 1100 WLTIVLTTVVCIMPVVAFRFLR 1121
Score = 294 bits (752), Expect = 5e-79
Identities = 158/400 (39%), Positives = 243/400 (60%), Gaps = 22/400 (5%)
Query: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
+Y N T+KY + TFLP NLFEQF AN YFLFL+IL +P + T++PL +
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYV-----QKCWKDVRVGDFIQMK 179
VL + +KD +D+ RH+ D +N R+ Q + Q+ W +V VGD I+++
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVN-------NRQSQVLINGILQQEQWMNVCVGDIIKLE 173
Query: 180 CNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV 239
N+ V AD+LLL SS+P+G+C++ETA LDGETN+K R + S+ + F ++
Sbjct: 174 NNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVI 233
Query: 240 CEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNN 299
CE PNN L+KF G + + + + +++LLRGC +RNTE G+VI+AG +TK M N+
Sbjct: 234 CEPPNNKLDKFSGTL-YWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNS 292
Query: 300 SGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGT----FEEHPPFDVPDANG 355
++KR+ I+R MN + + G L+ M +I A+G++IW F+ + P+D +
Sbjct: 293 GRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSA 352
Query: 356 SFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQC 415
F GF F + II+L ++PISLYVS+E+++LG +F++ D ++ + +
Sbjct: 353 FF-----SGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEA 407
Query: 416 RALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
R + E+LGQ++YIFSDKTGTLT+N MVF +C+I G Y
Sbjct: 408 RTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSY 447
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 424 bits (1091), Expect = e-118
Identities = 249/705 (35%), Positives = 388/705 (55%), Gaps = 50/705 (7%)
Query: 714 EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773
E Y+ +SPDE ALV AA + F SRTPE +T+ GT +T+ LL L F++ RKRM
Sbjct: 486 ELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIE-ELGTLVTYQLLAFLDFNNTRKRM 544
Query: 774 SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833
SV+VR+P G+I +Y+KGAD+++ + L V + + T HL +A +G
Sbjct: 545 SVIVRNP-EGQIKLYSKGADTILFEKLHPSNEV-----------LLSLTSDHLSEFAGEG 592
Query: 834 LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893
LRTL IA + + ++ F+ W +A A+ + RDE + + +E L LLGAT +ED+L
Sbjct: 593 LRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKL 652
Query: 894 QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLL-NQTDTVYTINTENQETCESI 952
QEGV +T+ +L A I++WVLTGDKQETA+NI ++C +L + + V+ I N
Sbjct: 653 QEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREE 712
Query: 953 LNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLE 1012
L A + L + + + SI E + + L+I+G +L + ++
Sbjct: 713 LRKAKQNLFGQNRNFSNGHVVCEKKQQLELDSIVEETITGDYALIINGHSLAHALESDVK 772
Query: 1013 KKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGI 1072
LEL C++V+CCR TPLQK+ +V+LV+ +TL+IGDGANDVSMI++A IG+GI
Sbjct: 773 NDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGI 832
Query: 1073 SGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQF 1132
SGQEG+QAV++SD++ +F++L++LLLVHG W Y R+ + + Y+ YKN + + FW+ F
Sbjct: 833 SGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGF 892
Query: 1133 FCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNL 1192
FCGFS+ T+ D W + FN+ +TSLP L G+ D+D+S + + P+LYK GQ + +N
Sbjct: 893 FCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNK 952
Query: 1193 STFWISMVDAFYQSLICFFIPYLAY---KGSD----IDVFTFGTPINTISLTTILLHQAM 1245
F+I ++ Y SL+ FFIPY A+ G D D +F + T + + + A+
Sbjct: 953 RKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIAL 1012
Query: 1246 EMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQ--LSNPTFYLVCF 1303
+ WT + V + GS +YF + ++ + P +V + L+ +LV
Sbjct: 1013 DTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVIL 1072
Query: 1304 LTPVVALLPRYFFLSLQGTCGKSLISKAQKIDKLPPDKRNLEIQSWRSRQRPAPVPEVAR 1363
LT V +++P F L K+D P + +I+ W+ Q+ A P R
Sbjct: 1073 LTTVASVMPVVAFRFL-------------KVDLYP--TLSDQIRRWQKAQKKARPPSSRR 1117
Query: 1364 P-THHPVSSITGQDF-----------SASTPKSSNPPKRKHVEES 1396
P T S +G F S ++ NPP +E++
Sbjct: 1118 PRTRRSSSRRSGYAFAHQEGYGELITSGKNMRAKNPPPTSGLEKT 1162
Score = 294 bits (753), Expect = 4e-79
Identities = 170/450 (37%), Positives = 258/450 (57%), Gaps = 20/450 (4%)
Query: 45 QRVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVIL 104
+R+V N+ +++ ++ Y NR T+KY + TFLP NLFEQF R AN YFL L+IL
Sbjct: 12 ERIVKANDREYNEKFQ-----YADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLIL 66
Query: 105 NWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQ 164
+P + T++PL +V+ + +KD +D+ RH+ D +N + +
Sbjct: 67 QLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQ--N 124
Query: 165 KCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQ 224
+ W +V+VGD I+++ N+ V AD+LLL SS+P+G+C++ETA LDGETNLK R + S+
Sbjct: 125 EKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSE 184
Query: 225 QEVQFEPEL-FHNTIVCEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAV 283
F +VCE PNN L+KF G + D ++ E ++LRGC +RNT
Sbjct: 185 LGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKD-SKHSLNNEKIILRGCILRNTSWCF 243
Query: 284 GIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNG-TF 342
G+VI+AG +TK M N+ ++KR+ I+R MN + + G LI + +I A+G+SIW T
Sbjct: 244 GMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTG 303
Query: 343 EEHPPFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDL 402
++ F N S GF F + II+L ++PISLYVS+E+++LG +F++ D
Sbjct: 304 DQFRTFLF--WNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDR 361
Query: 403 DLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAK 462
+Y + R + E+LGQI+YIFSDKTGTLT+N M F+RC+I G Y
Sbjct: 362 KMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYG------ 415
Query: 463 RLETPKELDSDGEEWTQYQCLSFSARWAQD 492
E +LD E + + + FS + D
Sbjct: 416 --EVHDDLDQKTEITQEKEPVDFSVKSQAD 443
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 410 bits (1053), Expect = e-114
Identities = 237/631 (37%), Positives = 347/631 (54%), Gaps = 55/631 (8%)
Query: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Y+A SPDEAALV A F +RTP V + G TF +L L F S RKRMSV+
Sbjct: 521 YQASSPDEAALVKGAKKLGFVFTARTPFSVIIEA-MGQEQTFGILNVLEFSSDRKRMSVI 579
Query: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
VR P +G + +Y KGAD+VI + L K K T HL+ +A +GLRT
Sbjct: 580 VRTP-SGRLRLYCKGADNVIFERLS------------KDSKYMEETLCHLEYFATEGLRT 626
Query: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
LC+A +SE ++ W +EA L +R + L E + +E L LLGAT IEDRLQ G
Sbjct: 627 LCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIEDRLQAG 686
Query: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
VP+TIATL +A I++WVLTGDKQETA+NI +SCRL++Q + + ++ + + +
Sbjct: 687 VPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILLKEDSLDATRAAITQH 746
Query: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFL 1016
+L + + L+IDG TL ++ + FL
Sbjct: 747 CTDLGNLLGKEN------------------------DVALIIDGHTLKYALSFEVRRSFL 782
Query: 1017 ELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQE 1076
+L C++V+CCR +PLQKS IV +V+ +++ +TL+IGDGANDV MIQ A +G+GISG E
Sbjct: 783 DLALSCKAVICCRVSPLQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNE 842
Query: 1077 GMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGF 1136
GMQA +SD+AI +F +L+KLLLVHG W Y+R+ + ++Y YKNV + W+ F GF
Sbjct: 843 GMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGF 902
Query: 1137 SSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFW 1196
S + + W + +N+ FT+LPP G+ ++ + E++L P+LYK QN E +N FW
Sbjct: 903 SGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFW 962
Query: 1197 ISMVDAFYQSLICFFIPYLAYK-------GSDIDVFTFGTPINTISLTTILLHQAMEMKT 1249
++A SLI F+ P A + G D G + T + T+ L +E
Sbjct: 963 GHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCLKAGLETTA 1022
Query: 1250 WTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWV-MEGQ----LSNPTFYLVCFL 1304
WT F + + GS L + + +Y+ PT P M GQ LS+ F+L FL
Sbjct: 1023 WTKFSHLAVWGSMLTWLVFFGIYSTIW-----PTIPIAPDMRGQATMVLSSAHFWLGLFL 1077
Query: 1305 TPVVALLPRYFFLSLQGTCGKSLISKAQKID 1335
P L+ + + + TC K+L+ + Q+++
Sbjct: 1078 VPTACLIEDVAWRAAKHTCKKTLLEEVQELE 1108
Score = 283 bits (723), Expect = 1e-75
Identities = 158/404 (39%), Positives = 230/404 (56%), Gaps = 29/404 (7%)
Query: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
++ N+ T KY++ TFLPR L+EQ R AN +FLF+ +L +P + R T++PL I
Sbjct: 67 KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLII 126
Query: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQK-------CWKDVRVGDFIQ 177
+L + IK+ +EDFKRH+ D A+N K++T V + WK+V VGD ++
Sbjct: 127 ILTIAGIKEIVEDFKRHKADNAVN---------KKKTIVLRNGMWHTIMWKEVAVGDIVK 177
Query: 178 MKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNT 237
+ + +PAD++LL SS+P +C++ETA+LDGETNLK R + + + + T
Sbjct: 178 VVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGLSHTADMQTREVLMKLSGT 237
Query: 238 IVCEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAML 297
I CE PN HL F G + ++ G + +LLRG +RNT+ GIV+Y GH+TK M
Sbjct: 238 IECEGPNRHLYDFTGNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQ 297
Query: 298 NNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEH----PPFDVPDA 353
N++ KRS +E+ N+ I GIL++M L+ + G WN + E D
Sbjct: 298 NSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSD 357
Query: 354 NGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSI 413
N Y LT IIL LIPISL V++E+VK Q F++ D D+Y D
Sbjct: 358 NFG---------YNLLTFIILYNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPA 408
Query: 414 QCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSH 457
R N+ E+LGQ++Y+FSDKTGTLT N M F++C+I G Y H
Sbjct: 409 MARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVTYGH 452
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 406 bits (1043), Expect = e-113
Identities = 231/633 (36%), Positives = 355/633 (56%), Gaps = 49/633 (7%)
Query: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Y+A SPDE ALV AA +F RTP+ V + G + LL L F S RKRMSV+
Sbjct: 486 YQAASPDEGALVRAAKQLNFVFTGRTPDSVIID-SLGQEERYELLNVLEFTSARKRMSVI 544
Query: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
VR P +G++ +Y KGAD+VI D L + + K + T KHL+ +A +GLRT
Sbjct: 545 VRTP-SGKLRLYCKGADTVIYDRLAETS------------KYKEITLKHLEQFATEGLRT 591
Query: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
LC A +SE DF+ W + + A S+ NR L E+ + +E L LLGAT IED+LQ+
Sbjct: 592 LCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQ 651
Query: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
VP+TI TL +A I++W+LTGDKQETA+NI HSC+LL + + IN + + L+
Sbjct: 652 VPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRH 711
Query: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFL 1016
L L+K + + L+IDGKTL + + FL
Sbjct: 712 CTTLGD--ALRKEN----------------------DFALIIDGKTLKYALTFGVRQYFL 747
Query: 1017 ELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQE 1076
+L C++V+CCR +PLQKS +V++V+ +++V+TL+IGDGANDVSMIQ A +G+GISG E
Sbjct: 748 DLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNE 807
Query: 1077 GMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGF 1136
G+QA SSD++I +FK+LK LL++HG W Y+R+++ ++Y YKN+ + W+ F GF
Sbjct: 808 GLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGF 867
Query: 1137 SSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFW 1196
S + + W + +N+ FT++PPL G+ ++ E +L PELYK+ QN+ +N FW
Sbjct: 868 SGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFW 927
Query: 1197 ISMVDAFYQSLICFFIPYLAYK-------GSDIDVFTFGTPINTISLTTILLHQAMEMKT 1249
+ ++ + S+I F+ P A + G D G + T + T+ L +E
Sbjct: 928 VHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSY 987
Query: 1250 WTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQL--SNPTFYLVCFLTPV 1307
WT F + + GS ++ + +Y++ P P E + S+ F++ PV
Sbjct: 988 WTWFSHIAIWGSIALWVVFFGIYSSLWPAI--PMAPDMSGEAAMLFSSGVFWMGLLFIPV 1045
Query: 1308 VALLPRYFFLSLQGTCGKSLISKAQKIDKLPPD 1340
+LL + ++ T K+L+ + Q+++ D
Sbjct: 1046 ASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQD 1078
Score = 286 bits (732), Expect = 1e-76
Identities = 163/395 (41%), Positives = 224/395 (56%), Gaps = 15/395 (3%)
Query: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
++ N T KY + TFLPR L+ QF R AN +FLF+ +L +P + R T++PL
Sbjct: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
Query: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIV 184
+L V IK+ +ED KRH+ D A+N ++ V W+ V VGD + +K E +
Sbjct: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVNVGDIVIIKGKEYI 165
Query: 185 PADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVCEKPN 244
PAD +LL SS+P +C++ET++LDGETNLK R + S + I CE PN
Sbjct: 166 PADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPN 225
Query: 245 NHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRY 304
HL F G + G + +LLRG +RNT+ GIV+Y GH+TK M N++ P
Sbjct: 226 RHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPL 285
Query: 305 KRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSALGG 364
K S +ER N+ I ILI M L+ +VG +IWN H D +L GG
Sbjct: 286 KLSNVERITNVQILILFCILIAMSLVCSVGSAIWN---RRHSGKDW------YLNLNYGG 336
Query: 365 F----YMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI 420
FLT IIL LIPISL V++E+VK Q +F++ DLD++ E TD + R N+
Sbjct: 337 ASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNL 396
Query: 421 AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
E+LGQ++YIFSDKTGTLT N M F++CTI G Y
Sbjct: 397 NEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAY 431
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 406 bits (1043), Expect = e-113
Identities = 231/633 (36%), Positives = 355/633 (56%), Gaps = 49/633 (7%)
Query: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Y+A SPDE ALV AA +F RTP+ V + G + LL L F S RKRMSV+
Sbjct: 501 YQAASPDEGALVRAAKQLNFVFTGRTPDSVIID-SLGQEERYELLNVLEFTSARKRMSVI 559
Query: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
VR P +G++ +Y KGAD+VI D L + + K + T KHL+ +A +GLRT
Sbjct: 560 VRTP-SGKLRLYCKGADTVIYDRLAETS------------KYKEITLKHLEQFATEGLRT 606
Query: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
LC A +SE DF+ W + + A S+ NR L E+ + +E L LLGAT IED+LQ+
Sbjct: 607 LCFAVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQ 666
Query: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
VP+TI TL +A I++W+LTGDKQETA+NI HSC+LL + + IN + + L+
Sbjct: 667 VPETIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRH 726
Query: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFL 1016
L L+K + + L+IDGKTL + + FL
Sbjct: 727 CTTLGD--ALRKEN----------------------DFALIIDGKTLKYALTFGVRQYFL 762
Query: 1017 ELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQE 1076
+L C++V+CCR +PLQKS +V++V+ +++V+TL+IGDGANDVSMIQ A +G+GISG E
Sbjct: 763 DLALSCKAVICCRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNE 822
Query: 1077 GMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGF 1136
G+QA SSD++I +FK+LK LL++HG W Y+R+++ ++Y YKN+ + W+ F GF
Sbjct: 823 GLQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGF 882
Query: 1137 SSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFW 1196
S + + W + +N+ FT++PPL G+ ++ E +L PELYK+ QN+ +N FW
Sbjct: 883 SGQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFW 942
Query: 1197 ISMVDAFYQSLICFFIPYLAYK-------GSDIDVFTFGTPINTISLTTILLHQAMEMKT 1249
+ ++ + S+I F+ P A + G D G + T + T+ L +E
Sbjct: 943 VHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSY 1002
Query: 1250 WTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQL--SNPTFYLVCFLTPV 1307
WT F + + GS ++ + +Y++ P P E + S+ F++ PV
Sbjct: 1003 WTWFSHIAIWGSIALWVVFFGIYSSLWPAI--PMAPDMSGEAAMLFSSGVFWMGLLFIPV 1060
Query: 1308 VALLPRYFFLSLQGTCGKSLISKAQKIDKLPPD 1340
+LL + ++ T K+L+ + Q+++ D
Sbjct: 1061 ASLLLDVVYKVIKRTAFKTLVDEVQELEAKSQD 1093
Score = 287 bits (734), Expect = 6e-77
Identities = 165/421 (39%), Positives = 233/421 (55%), Gaps = 21/421 (4%)
Query: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
++ N T KY + TFLPR L+ QF R AN +FLF+ +L +P + R T++PL
Sbjct: 48 KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLLF 107
Query: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIV 184
+L V IK+ +ED KRH+ D A+N ++ V W+ V VG+ +++ E +
Sbjct: 108 ILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVH--WEKVAVGEIVKVTNGEHL 165
Query: 185 PADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVCEKPN 244
PAD++ L SS+P +C++ET++LDGETNLK R + S + I CE PN
Sbjct: 166 PADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKDVDSLMRISGRIECESPN 225
Query: 245 NHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRY 304
HL F G + G + +LLRG +RNT+ GIV+Y GH+TK M N++ P
Sbjct: 226 RHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPL 285
Query: 305 KRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSALGG 364
K S +ER N+ I ILI M L+ +VG +IWN H D +L GG
Sbjct: 286 KLSNVERITNVQILILFCILIAMSLVCSVGSAIWN---RRHSGKDW------YLNLNYGG 336
Query: 365 F----YMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI 420
FLT IIL LIPISL V++E+VK Q +F++ DLD++ E TD + R N+
Sbjct: 337 ASNFGLNFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNL 396
Query: 421 AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQY 480
E+LGQ++YIFSDKTGTLT N M F++CTI G Y H + P++ +EW
Sbjct: 397 NEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGH------VPEPEDYGCSPDEWQNS 450
Query: 481 Q 481
Q
Sbjct: 451 Q 451
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 387 bits (995), Expect = e-107
Identities = 241/685 (35%), Positives = 356/685 (51%), Gaps = 83/685 (12%)
Query: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Y+A SPDE ALV+AA + F ++RT +T+ GT T+++L L F+S RKRMS++
Sbjct: 548 YQAASPDEGALVNAARNFGFAFLARTQNTITIS-ELGTERTYNVLAILDFNSDRKRMSII 606
Query: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
VR P G I +Y KGAD+VI + L ++ + TQ LD++A + LRT
Sbjct: 607 VRTP-EGNIKLYCKGADTVIYERLH------------RMNPTKQETQDALDIFANETLRT 653
Query: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
LC+ K + E++F W A + NRDE L + + +E L LLGAT IED+LQ+G
Sbjct: 654 LCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDG 713
Query: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
VP+TI+ L +A I++WVLTGDK+ETA NI +C LL + T+ C
Sbjct: 714 VPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTI----------------CY 757
Query: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAG---LVIDGKTLNAIFQGKL-- 1011
E++ + +++ G P + E+ P G L+I G LN I K
Sbjct: 758 GEDINSLLHARMENQRNRGGVYAKFAPPV-QESFFPPGGNRALIITGSWLNEILLEKKTK 816
Query: 1012 ---------------------------------EKKFLELTQYCRSVLCCRSTPLQKSMI 1038
+K F++L C +V+CCR TP QK+M+
Sbjct: 817 RNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMV 876
Query: 1039 VKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLL 1098
V LV+ + +TL+IGDGANDV+MI+ A IG+GISGQEGMQAVMSSD++ +F++L++LL
Sbjct: 877 VDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLL 936
Query: 1099 LVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLP 1158
LVHG W Y R+ + + Y+ YKN + + FWY FF G+S+ T + W + +N+ +TSLP
Sbjct: 937 LVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLP 996
Query: 1159 PLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIP---YL 1215
L+ G+LD+D+S + L P LY GQ +N F++S++ S+I FFIP YL
Sbjct: 997 VLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL 1056
Query: 1216 AYKGSD----IDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLL 1271
G D D +F I + + T+ ++ WT + + GS +YF +
Sbjct: 1057 QTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFD 1116
Query: 1272 YNATCVICNSPTNPYW--VMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLIS 1329
+++ + P+ + L P +L LT V LLP L T S
Sbjct: 1117 FHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESD 1176
Query: 1330 KAQKIDKLPPDKRNLEIQSWRSRQR 1354
K QK KR + W+ RQ+
Sbjct: 1177 KIQK-----HRKRLKAEEQWQRRQQ 1196
Score = 307 bits (786), Expect = 6e-83
Identities = 176/420 (41%), Positives = 248/420 (59%), Gaps = 14/420 (3%)
Query: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
+Y N T KY FTF+P NLFEQF R ANLYFL L+IL +P + T++PL +
Sbjct: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150
Query: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIV 184
VL V IKD ++D RH+ DK IN + K+ + WK+++VGD I++K N+ V
Sbjct: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVI--KDGRFKVAKWKEIQVGDVIRLKKNDFV 208
Query: 185 PADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPEL--FHNTIVCEK 242
PADILLL SS+PN +C++ETA LDGETNLK + ++ + Q +Q E L F I CE+
Sbjct: 209 PADILLLSSSEPNSLCYVETAELDGETNLKFKMSLE-ITDQYLQREDTLATFDGFIECEE 267
Query: 243 PNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGP 302
PNN L+KF G + + T + +LLRGC IRNT+ G+VI+AG +TK M N+
Sbjct: 268 PNNRLDKFTGTLFWRN-TSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKT 326
Query: 303 RYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHP--PFDVPDANGSFLPS 360
R+KR+KI+ MN ++ +LIL+ A+GH+ W +D D S+
Sbjct: 327 RFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYR-- 384
Query: 361 ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI 420
GF +F II+L ++PISLYVS+E+++LGQ F++ DL +Y E D + R +
Sbjct: 385 ---GFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441
Query: 421 AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQY 480
E LGQI YIFSDKTGTLT+N M F++C I G Y +A + +++ W Y
Sbjct: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQ-HNHNKIEQVDFSWNTY 500
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 369 bits (948), Expect = e-102
Identities = 224/611 (36%), Positives = 340/611 (55%), Gaps = 40/611 (6%)
Query: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Y + SPDE ALV FT + + + + F LL L FDSVR+RMSV+
Sbjct: 504 YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVI 563
Query: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
V+ TGEI ++ KGADS I + +E K+ +IRAR +++ A +GLRT
Sbjct: 564 VKSA-TGEIYLFCKGADSSIFPRV----------IEGKVDQIRARVERN----AVEGLRT 608
Query: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
LC+A K + +E++ + A+ +L +R++ L E + +E LTLLGAT +EDRLQE
Sbjct: 609 LCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEK 668
Query: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
DTI L++AGI++WVLTGDK ETA ++C+L + + + T+ E E L+
Sbjct: 669 AADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIE--EQSLHDV 726
Query: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQ-------G 1009
L EL K + G ++++ + + GL+IDG L+ I + G
Sbjct: 727 LFELS------KTVLRHSGSLTRDNLSGLSAD--MQDYGLIIDGAALSLIMKPREDGSSG 778
Query: 1010 KLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVR-DKLRVMTLSIGDGANDVSMIQAADI 1068
+ FLE+ + C +VLCCR PLQK+ IVKL++ K +TL+IGDGANDVSMI A +
Sbjct: 779 NYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHV 838
Query: 1069 GIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLF 1128
GIG+ G+EG QA +SD+AI +FKHLKK+LLVHGH+ Y R++ +V Y+ YKNVC++ F
Sbjct: 839 GIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQF 898
Query: 1129 WYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSE 1188
YQFFCGFS T+ D + +N+ FTSLP L++ ++++ + + L P LY+ +
Sbjct: 899 LYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNA 958
Query: 1189 CYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDV-------FTFGTPINTISLTTILL 1241
F + + +L+ FF Y ++ + + +TFGT + T+ + T+ L
Sbjct: 959 LLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTL 1018
Query: 1242 HQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLV 1301
A++ WT + V+ GS L Y + SLL+ + Y+V LS+ +L
Sbjct: 1019 KLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLA 1078
Query: 1302 CFLTPVVALLP 1312
L ++LLP
Sbjct: 1079 IVLLVTISLLP 1089
Score = 256 bits (655), Expect = 9e-68
Identities = 155/405 (38%), Positives = 225/405 (55%), Gaps = 20/405 (4%)
Query: 62 VSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWM---PSMEVFHREIT 118
+ +RYP NR ++KYT + F+P+NLFEQF R AN YFL + ++ + P+ V +
Sbjct: 41 IPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSPV----TS 96
Query: 119 MLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQM 178
LPL V+ V IK G ED+ RH+ D A+N + + + V+K + +RVGD + +
Sbjct: 97 GLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGK--LVRKQSRKLRVGDIVMV 154
Query: 179 KCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVV---KGFSQQEVQFEPELFH 235
K +E P D++ L S+ +G CH+ TASLDGE++ K V KGF +E + H
Sbjct: 155 KEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEE---DIGGLH 211
Query: 236 NTIVCEKPNNHLNKFKG----YMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGH 291
TI CE+P L KF G Y + D G E+LLLRG T++NTE G+ IY G
Sbjct: 212 ATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGM 271
Query: 292 ETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGT-FEEHPPFDV 350
ETK LN KRS +E+ MN + + ILI LI V +W F + P ++
Sbjct: 272 ETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQ 331
Query: 351 PDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETD 410
+ L F FL ++L +IP+S+YV++E+ K +F++ D D++DEET
Sbjct: 332 KTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETG 391
Query: 411 LSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
++ E+LGQ++YIF+DKTGTLTEN M F+ C I G Y
Sbjct: 392 EGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVY 436
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 369 bits (948), Expect = e-102
Identities = 224/611 (36%), Positives = 340/611 (55%), Gaps = 40/611 (6%)
Query: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776
Y + SPDE ALV FT + + + + F LL L FDSVR+RMSV+
Sbjct: 504 YISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEILSFDSVRRRMSVI 563
Query: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836
V+ TGEI ++ KGADS I + +E K+ +IRAR +++ A +GLRT
Sbjct: 564 VKSA-TGEIYLFCKGADSSIFPRV----------IEGKVDQIRARVERN----AVEGLRT 608
Query: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896
LC+A K + +E++ + A+ +L +R++ L E + +E LTLLGAT +EDRLQE
Sbjct: 609 LCVAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEK 668
Query: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956
DTI L++AGI++WVLTGDK ETA ++C+L + + + T+ E E L+
Sbjct: 669 AADTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIE--EQSLHDV 726
Query: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQ-------G 1009
L EL K + G ++++ + + GL+IDG L+ I + G
Sbjct: 727 LFELS------KTVLRHSGSLTRDNLSGLSAD--MQDYGLIIDGAALSLIMKPREDGSSG 778
Query: 1010 KLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVR-DKLRVMTLSIGDGANDVSMIQAADI 1068
+ FLE+ + C +VLCCR PLQK+ IVKL++ K +TL+IGDGANDVSMI A +
Sbjct: 779 NYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHV 838
Query: 1069 GIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLF 1128
GIG+ G+EG QA +SD+AI +FKHLKK+LLVHGH+ Y R++ +V Y+ YKNVC++ F
Sbjct: 839 GIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQF 898
Query: 1129 WYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSE 1188
YQFFCGFS T+ D + +N+ FTSLP L++ ++++ + + L P LY+ +
Sbjct: 899 LYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNA 958
Query: 1189 CYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDV-------FTFGTPINTISLTTILL 1241
F + + +L+ FF Y ++ + + +TFGT + T+ + T+ L
Sbjct: 959 LLRWRVFIYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTL 1018
Query: 1242 HQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLV 1301
A++ WT + V+ GS L Y + SLL+ + Y+V LS+ +L
Sbjct: 1019 KLALDTHYWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLA 1078
Query: 1302 CFLTPVVALLP 1312
L ++LLP
Sbjct: 1079 IVLLVTISLLP 1089
Score = 256 bits (655), Expect = 9e-68
Identities = 155/405 (38%), Positives = 225/405 (55%), Gaps = 20/405 (4%)
Query: 62 VSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWM---PSMEVFHREIT 118
+ +RYP NR ++KYT + F+P+NLFEQF R AN YFL + ++ + P+ V +
Sbjct: 41 IPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSPV----TS 96
Query: 119 MLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQM 178
LPL V+ V IK G ED+ RH+ D A+N + + + V+K + +RVGD + +
Sbjct: 97 GLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGK--LVRKQSRKLRVGDIVMV 154
Query: 179 KCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVV---KGFSQQEVQFEPELFH 235
K +E P D++ L S+ +G CH+ TASLDGE++ K V KGF +E + H
Sbjct: 155 KEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEE---DIGGLH 211
Query: 236 NTIVCEKPNNHLNKFKG----YMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGH 291
TI CE+P L KF G Y + D G E+LLLRG T++NTE G+ IY G
Sbjct: 212 ATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGM 271
Query: 292 ETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGT-FEEHPPFDV 350
ETK LN KRS +E+ MN + + ILI LI V +W F + P ++
Sbjct: 272 ETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQ 331
Query: 351 PDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETD 410
+ L F FL ++L +IP+S+YV++E+ K +F++ D D++DEET
Sbjct: 332 KTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETG 391
Query: 411 LSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
++ E+LGQ++YIF+DKTGTLTEN M F+ C I G Y
Sbjct: 392 EGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVY 436
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 361 bits (927), Expect = 2e-99
Identities = 226/612 (36%), Positives = 338/612 (55%), Gaps = 51/612 (8%)
Query: 708 TDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFD 767
++LA + Y A SPDE ALV AA + + E + V+ G + LL L FD
Sbjct: 515 SNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKT-LGKLERYKLLHILEFD 573
Query: 768 SVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLD 827
S R+RMSV+V+ P +GE +++ KGA+S I+ P C+ +EK T+ H+D
Sbjct: 574 SDRRRMSVIVQAP-SGEKLLFAKGAESSIL-----PKCIGG-EIEK--------TRIHVD 618
Query: 828 LYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGAT 887
+A GLRTLCIA + + +++ EA +L R+E L Q +E L LLGAT
Sbjct: 619 EFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGAT 678
Query: 888 GIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQE 947
+EDRLQ+ V +TI LR AGI++WVLTGDK ETAV+++ SC ++T + + + +
Sbjct: 679 AVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILELINQKSD 738
Query: 948 TCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIF 1007
+ CA +Q R+L + IT + V+ + GLV+DG +L+
Sbjct: 739 S-----ECA----EQLRQLAR---------------RITEDHVI-QHGLVVDGTSLSLAL 773
Query: 1008 QGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVR-DKLRVMTLSIGDGANDVSMIQAA 1066
+ + EK F+E+ + C +VLCCR PLQK+ +++L++ + +TL++GDGANDVSMIQ A
Sbjct: 774 R-EHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGANDVSMIQEA 832
Query: 1067 DIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNL 1126
+GIGI G+EG QA +SD+AI RFK L KLL VHGH+ Y R+A +V Y+ YKNVC++
Sbjct: 833 HVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFYKNVCFITP 892
Query: 1127 LFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQN 1186
F YQF+C FS T+ D + +N+ FTSLP L++ +L++ + L P LY+
Sbjct: 893 QFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKPTLYRDISK 952
Query: 1187 SECYNLSTFWISMVDAFYQSLICFFIPYLAY--------KGSDIDVFTFGTPINTISLTT 1238
+ ++ TF + F + I FF YL G +TFGT + T+ + T
Sbjct: 953 NRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTLVFTVMVIT 1012
Query: 1239 ILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTF 1298
+ + A+E WT + +V GS + YF+ SL Y N Y+V LS+ +
Sbjct: 1013 VTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFIQLLSSGSA 1072
Query: 1299 YLVCFLTPVVAL 1310
+ L V L
Sbjct: 1073 WFAIILMVVTCL 1084
Score = 255 bits (652), Expect = 2e-67
Identities = 157/433 (36%), Positives = 231/433 (53%), Gaps = 19/433 (4%)
Query: 49 FPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWM- 107
FP N ++ +++ NR ++KYT++ F+P+NLFEQF R AN YFL + ++ M
Sbjct: 28 FPQNGLY------TPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMI 81
Query: 108 --PSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQK 165
P+ V + LPL V+ V IK G ED+ RH D +N +Y + V+
Sbjct: 82 DTPTSPV----TSGLPLFFVITVTAIKQGYEDWLRHNSDNEVN--GAPVYVVRSGGLVKT 135
Query: 166 CWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQ 225
K++RVGD +++ +EI PAD++LL S +G CH+ TASLDGETNLK V +
Sbjct: 136 RSKNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALL 195
Query: 226 EVQFEPELFHNTIVCEKPNNHLNKFKGYM---EHPDQTRTGFGCESLLLRGCTIRNTEMA 282
+ + I C++P L +F G M + ++ G ESLLLRG ++NT+
Sbjct: 196 QTVANLDTLVAVIECQQPEADLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEI 255
Query: 283 VGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTF 342
G+ +Y G ETK LN KRS +E+ MN + + ILI +I + W
Sbjct: 256 FGVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEE 315
Query: 343 EEHPPFDVPDANGSFLPSALGGFYM-FLTMIILLQVLIPISLYVSIELVKLGQVFFLSND 401
+ P+ S + F FL ++L +IPISLYV++E+ K FF+ D
Sbjct: 316 KWDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWD 375
Query: 402 LDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENA 461
LDLY EE+D Q ++ E+LGQ++Y+F+DKTGTLTEN+M FR C+I G +Y
Sbjct: 376 LDLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGR 435
Query: 462 KRLETPKELDSDG 474
E P S+G
Sbjct: 436 LVPEGPTPDSSEG 448
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 361 bits (926), Expect = 3e-99
Identities = 218/629 (34%), Positives = 333/629 (52%), Gaps = 38/629 (6%)
Query: 714 EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773
E Y + SPDE ALV A Y FT + + V + + LL TL FD+VR+RM
Sbjct: 491 ELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRM 550
Query: 774 SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833
SV+V+ G+I+++ KGADS + ++ N E +L K+ H++ A DG
Sbjct: 551 SVIVKTQ-EGDILLFCKGADSAVFPRVQ--------NHEIELTKV------HVERNAMDG 595
Query: 834 LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893
RTLC+A K ++ +D+ R EA+ +L +R+E + + +E + L+GAT +ED+L
Sbjct: 596 YRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKL 655
Query: 894 QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESIL 953
Q+ +TI L AG+++WVLTGDK ETA + ++CRL + + T+ E E
Sbjct: 656 QDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESE--- 712
Query: 954 NCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVV-PEAGLVIDGKTLNAIFQGKLE 1012
+ + EL RK P T S E GL+IDG TL+ I +
Sbjct: 713 ----RKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQD 768
Query: 1013 KK-------FLELTQYCRSVLCCRSTPLQKSMIVKLVRD-KLRVMTLSIGDGANDVSMIQ 1064
FL++ C +VLCCR PLQK+ IV++V++ K +TLSIGDGANDVSMI
Sbjct: 769 SSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMIL 828
Query: 1065 AADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYV 1124
+ +GIGI G+EG QA +SD+++ +FKHLKKLLL HGH Y R+A +V Y+ YKN+C++
Sbjct: 829 ESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFI 888
Query: 1125 NLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSG 1184
F YQFFCGFS + D + +N+ FTSLP L + +L++ I+ +TL + P LY
Sbjct: 889 LPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKI 948
Query: 1185 QNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDV-------FTFGTPINTISLT 1237
+ L F A ++ + FF Y ++ + ++ +TFGT + T+ +
Sbjct: 949 SGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVF 1008
Query: 1238 TILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPT 1297
T+ L A++ + WT + V+ GS Y S + Y+V LS+ +
Sbjct: 1009 TVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVS 1068
Query: 1298 FYLVCFLTPVVALLPRYFFLSLQGTCGKS 1326
+L L ++L P + L+ +S
Sbjct: 1069 TWLAIILLIFISLFPEILLIVLKNVRRRS 1097
Score = 253 bits (646), Expect = 9e-67
Identities = 148/416 (35%), Positives = 225/416 (54%), Gaps = 10/416 (2%)
Query: 46 RVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILN 105
R VF N + +++R+ NR ++KYTL+ FLP+NLFEQF R AN YFL + ++
Sbjct: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
Query: 106 WMPSMEVFHREITM-LPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQ 164
+++ +T LPL V+ V IK G ED+ RHR D +N S + I E ++ V+
Sbjct: 83 --VTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKR--VR 138
Query: 165 KCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQ 224
K + ++VGD ++++ +E P D++LL S +G C++ TASLDGE+N K V+
Sbjct: 139 KESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIA 198
Query: 225 QEVQFEPELFHNTIVCEKPNNHLNKFKG----YMEHPDQTRTGFGCESLLLRGCTIRNTE 280
+ I CE+P L KF G Y + G E+LLL+G T++NTE
Sbjct: 199 LCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTE 258
Query: 281 MAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNG 340
G+ +Y G ETK LN G KRS +E+ +N + + IL+ + +W
Sbjct: 259 KIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQS 318
Query: 341 T-FEEHPPFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLS 399
T + + P ++ L F FL+ ++L +IP+S+YV++E+ K FF+S
Sbjct: 319 TPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFIS 378
Query: 400 NDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
D D YDEE + ++ E+LGQ+ Y+F+DKTGTLTEN M F C I G +Y
Sbjct: 379 WDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 361 bits (926), Expect = 3e-99
Identities = 218/629 (34%), Positives = 333/629 (52%), Gaps = 38/629 (6%)
Query: 714 EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773
E Y + SPDE ALV A Y FT + + V + + LL TL FD+VR+RM
Sbjct: 491 ELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRM 550
Query: 774 SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833
SV+V+ G+I+++ KGADS + ++ N E +L K+ H++ A DG
Sbjct: 551 SVIVKTQ-EGDILLFCKGADSAVFPRVQ--------NHEIELTKV------HVERNAMDG 595
Query: 834 LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893
RTLC+A K ++ +D+ R EA+ +L +R+E + + +E + L+GAT +ED+L
Sbjct: 596 YRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKL 655
Query: 894 QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESIL 953
Q+ +TI L AG+++WVLTGDK ETA + ++CRL + + T+ E E
Sbjct: 656 QDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESE--- 712
Query: 954 NCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVV-PEAGLVIDGKTLNAIFQGKLE 1012
+ + EL RK P T S E GL+IDG TL+ I +
Sbjct: 713 ----RKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQD 768
Query: 1013 KK-------FLELTQYCRSVLCCRSTPLQKSMIVKLVRD-KLRVMTLSIGDGANDVSMIQ 1064
FL++ C +VLCCR PLQK+ IV++V++ K +TLSIGDGANDVSMI
Sbjct: 769 SSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMIL 828
Query: 1065 AADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYV 1124
+ +GIGI G+EG QA +SD+++ +FKHLKKLLL HGH Y R+A +V Y+ YKN+C++
Sbjct: 829 ESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFI 888
Query: 1125 NLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSG 1184
F YQFFCGFS + D + +N+ FTSLP L + +L++ I+ +TL + P LY
Sbjct: 889 LPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKI 948
Query: 1185 QNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDV-------FTFGTPINTISLT 1237
+ L F A ++ + FF Y ++ + ++ +TFGT + T+ +
Sbjct: 949 SGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVF 1008
Query: 1238 TILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPT 1297
T+ L A++ + WT + V+ GS Y S + Y+V LS+ +
Sbjct: 1009 TVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVS 1068
Query: 1298 FYLVCFLTPVVALLPRYFFLSLQGTCGKS 1326
+L L ++L P + L+ +S
Sbjct: 1069 TWLAIILLIFISLFPEILLIVLKNVRRRS 1097
Score = 253 bits (646), Expect = 9e-67
Identities = 148/416 (35%), Positives = 225/416 (54%), Gaps = 10/416 (2%)
Query: 46 RVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILN 105
R VF N + +++R+ NR ++KYTL+ FLP+NLFEQF R AN YFL + ++
Sbjct: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
Query: 106 WMPSMEVFHREITM-LPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQ 164
+++ +T LPL V+ V IK G ED+ RHR D +N S + I E ++ V+
Sbjct: 83 --VTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKR--VR 138
Query: 165 KCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQ 224
K + ++VGD ++++ +E P D++LL S +G C++ TASLDGE+N K V+
Sbjct: 139 KESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIA 198
Query: 225 QEVQFEPELFHNTIVCEKPNNHLNKFKG----YMEHPDQTRTGFGCESLLLRGCTIRNTE 280
+ I CE+P L KF G Y + G E+LLL+G T++NTE
Sbjct: 199 LCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTE 258
Query: 281 MAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNG 340
G+ +Y G ETK LN G KRS +E+ +N + + IL+ + +W
Sbjct: 259 KIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQS 318
Query: 341 T-FEEHPPFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLS 399
T + + P ++ L F FL+ ++L +IP+S+YV++E+ K FF+S
Sbjct: 319 TPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFIS 378
Query: 400 NDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
D D YDEE + ++ E+LGQ+ Y+F+DKTGTLTEN M F C I G +Y
Sbjct: 379 WDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 338 bits (868), Expect = 2e-92
Identities = 227/677 (33%), Positives = 354/677 (52%), Gaps = 80/677 (11%)
Query: 714 EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773
+ Y+A SPDE ALV AA + + +SRT + VT+ + G + +L + F+S RKRM
Sbjct: 586 QLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTI-MELGEERVYQVLAIMDFNSTRKRM 644
Query: 774 SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833
SV+VR P G I +YTKGAD+VI + L + + T++ L +A++
Sbjct: 645 SVLVRKP-EGAICLYTKGADTVIFERLH------------RRGAMEFATEEALAAFAQET 691
Query: 834 LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893
LRTLC+A + V+E+ + W +EA L NR + L + LLGAT IEDRL
Sbjct: 692 LRTLCLAYREVAEDIYEDWQQRHQEASLLLQNRAQALQQ----------LLGATAIEDRL 741
Query: 894 QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTV------------YTI 941
Q+GVP+TI L+++ I++WVLTGDKQETAVNI +C LL++ + Y
Sbjct: 742 QDGVPETIKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWE 801
Query: 942 NTENQETCESILNCALEEL-------KQFRELQKPDRKLF-----------------GFR 977
N+ N T ES+ L + K L+K R L F
Sbjct: 802 NSNNLLTRESLSQVKLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFL 861
Query: 978 LPSKTPSITSEAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSM 1037
+ + +P A + E+ F++L C++V+CCR TP QK++
Sbjct: 862 YARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKAL 921
Query: 1038 IVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKL 1097
IV LV+ +V+TL+IGDGAND++MI+ AD+G+G++GQEGMQAV +SDF + +F L++L
Sbjct: 922 IVALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRL 981
Query: 1098 LLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSL 1157
LLVHG W Y R+ + + Y+ YK++ + + W+ + GF+ + + W + FNL +++L
Sbjct: 982 LLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTL 1041
Query: 1158 PPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPY--- 1214
P L G+ ++D+SAE L PELY GQ E +N F ++ SL+ FF+
Sbjct: 1042 PVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMTLWIS 1101
Query: 1215 --LAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLY 1272
A S D +F + L +I + + +K WT +L S Y +++
Sbjct: 1102 RDTAGPASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTT 1161
Query: 1273 NATCVICNSPTN-PYWVME-GQLSNPTFYLVCFLT------PVVALLPRYFFLSLQGTCG 1324
+ + SPT P+ + +S+P+ LV L+ PV+AL R F +L
Sbjct: 1162 QSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLAL--RVIFPAL----- 1214
Query: 1325 KSLISKAQKIDKLPPDK 1341
K L +K +K+++ P ++
Sbjct: 1215 KELRAKEEKVEEGPSEE 1231
Score = 265 bits (677), Expect = 2e-70
Identities = 149/407 (36%), Positives = 238/407 (58%), Gaps = 9/407 (2%)
Query: 64 RRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLA 123
++Y N T KY ++FLP NL+EQFHR +NL+FL ++IL +P + P+
Sbjct: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
Query: 124 IVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEI 183
+LF+ +D ++D RH+ D+AIN +I K ++ QK W+D+ VGD + ++ + I
Sbjct: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGK--SFKQKKWQDLCVGDVVCLRKDNI 248
Query: 184 VPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPEL-FHNTIVCEK 242
VPAD+LLL S++P+ +C++ET +DGETNLK R + ++ + F T+ CE
Sbjct: 249 VPADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEA 308
Query: 243 PNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGP 302
PN+ ++ F G +E D+ + +LLLRGC IRNT+ G+VIYAG +TK M N
Sbjct: 309 PNSRMHHFVGCLEWNDK-KYSLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCGKI 367
Query: 303 RYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSAL 362
KR+K++ MN + ++L+CL+ A G F++H + + +GS + A
Sbjct: 368 HLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYY-LSGVHGSSV--AA 424
Query: 363 GGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAE 422
F++F + +ILL V IP+S+++ E + LG F+ D+ +Y + D+ + R+ ++ +
Sbjct: 425 ESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTSLND 484
Query: 423 DLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKE 469
LGQ++YIFSDKTGTLT+N + F +C I G Y A PKE
Sbjct: 485 HLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEA--TTRPKE 529
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 273 bits (699), Expect = 7e-73
Identities = 197/624 (31%), Positives = 306/624 (49%), Gaps = 70/624 (11%)
Query: 690 ILESGSGTSLEEALEAPATDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVR 749
+ ES +G + E D + Y+A SPDE ALV + TLVSR + ++
Sbjct: 557 VYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLK 616
Query: 750 LPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDI 809
P G L+F +L F S KRM V+VR T EI Y KGAD + +++
Sbjct: 617 TPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQ-------- 668
Query: 810 NMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDEL 869
++ AR+GLRTL +AKK ++EE ++ + S +A+ S+ +R
Sbjct: 669 --------YNDWLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLK 720
Query: 870 LMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSC 929
+ + LE ++ LL TG+ED+LQ V T+ LR AGI++W+LTGDK ETA IA S
Sbjct: 721 VAAVVESLEREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSS 780
Query: 930 RLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEA 989
L+++T ++ Q T + EL FR
Sbjct: 781 HLVSRTQDIHIFR---QVTSRGEAHL---ELNAFRRKH---------------------- 812
Query: 990 VVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVM 1049
+ LVI G +L + E +F+EL C +V+CCR +P QK+ IV L++
Sbjct: 813 ---DCALVISGDSLEVCLK-YYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRR 868
Query: 1050 TLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRL 1109
T +IGDG NDVSMIQAAD GIGI G+EG QA +++DF+IT+F+H+ +LL+VHG Y R
Sbjct: 869 TCAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRS 928
Query: 1110 ARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFG-VLDKD 1168
A + + +++ + + + F+S + + M+ + +T P VF VLD+D
Sbjct: 929 AALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFP--VFSLVLDQD 986
Query: 1169 ISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFG 1228
+ E + PELYK + TF I ++ + YQ I + + ++ + V
Sbjct: 987 VKPEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVHVVAIS 1046
Query: 1229 TPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMY--FLVSLLYNATCVICNSPTNPY 1286
T + T LL A+ ++TW H ++++ FL ++ SL + N Y
Sbjct: 1047 F---TALILTELLMVALTVRTW---HWLMVVAEFLSLGCYVSSLAF----------LNEY 1090
Query: 1287 WVMEGQLSNPTFYLVCFLTPVVAL 1310
+ + G++S F V F+T V L
Sbjct: 1091 FGI-GRVSFGAFLDVAFITTVTFL 1113
Score = 157 bits (398), Expect = 5e-38
Identities = 124/459 (27%), Positives = 217/459 (47%), Gaps = 46/459 (10%)
Query: 60 EEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITM 119
E+ ++P N KY +FTF+P L+EQF + NLYFL + ++P++++ +
Sbjct: 124 EKCEEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYW 183
Query: 120 LPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYER-KEQTYVQKCWKDVRVGDFIQM 178
PL VL V M ++ +++F+R + DK +N ++Y + + VQ D++VGD I +
Sbjct: 184 APLGFVLAVTMTREAIDEFRRFQRDKEVNS---QLYSKLTVRGKVQVKSSDIQVGDLIIV 240
Query: 179 KCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTI 238
+ N+ +P+D++ L +S+ G C + T LDGET+ K + V Q + +
Sbjct: 241 EKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQLPALGDLFSISAYV 300
Query: 239 VCEKPNNHLNKFKGYMEHPDQTRTGFGCESL--LLRGCTIRNTEMAVGIVIYAGHETKAM 296
+KP ++ F+G D S+ L TI + +G+VIY G ET+++
Sbjct: 301 YAQKPQMDIHSFEGTFTREDSDPPIHESLSIENTLWASTIVASGTVIGVVIYTGKETRSV 360
Query: 297 LNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGS 356
+N S P+ K ++ +N L + V SI T
Sbjct: 361 MNTSNPKNKVGLLDLELN--------RLTKALFLALVALSIVMVT--------------- 397
Query: 357 FLPSALGGFYMFL-TMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQC 415
L +G +Y L ++L +IPISL V++++ K + + D E
Sbjct: 398 -LQGFVGPWYRNLFRFLLLFSYIIPISLRVNLDMGKAVYGWMMMKD------ENIPGTVV 450
Query: 416 RALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSD-G 474
R I E+LG++ Y+ +DKTGTLT+N+M+F+R + Y +T E+ S
Sbjct: 451 RTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYG-------ADTMDEIQSHVR 503
Query: 475 EEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARV 513
+ ++Q Q + P ++Q A +R+S S+R+
Sbjct: 504 DSYSQMQSQAGGNNTGSTP-LRKAQSSAPKVRKSVSSRI 541
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 265 bits (678), Expect = 2e-70
Identities = 188/586 (32%), Positives = 291/586 (49%), Gaps = 63/586 (10%)
Query: 690 ILESGSGTSLEEALEAPATDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVR 749
+ ES T EA E D R Y+A SPDE ALV + TLV R + +R
Sbjct: 472 VYESNGVTDQAEA-EKQYEDSCR---VYQASSPDEVALVQWTESVGLTLVGRDQSSMQLR 527
Query: 750 LPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDI 809
P L F++L F KRM ++VR TGEI Y KGAD V+ +++
Sbjct: 528 TPGDQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQ-------- 579
Query: 810 NMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDEL 869
++ AR+GLR L +AKK ++EE ++ + + +A+ S+ +R
Sbjct: 580 --------YNDWLEEECGNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLK 631
Query: 870 LMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSC 929
+ + LE ++ LL TG+ED+LQ V T+ TLR AGI++W+LTGDK ETA A +
Sbjct: 632 VATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNA 691
Query: 930 RLL--NQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITS 987
L+ NQ V+ + T E A EL FR
Sbjct: 692 HLVTRNQDIHVFRLVTNRGE--------AHLELNAFRRKH-------------------- 723
Query: 988 EAVVPEAGLVIDGKTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLR 1047
+ LVI G +L + E +F+EL C +V+CCR P QK+ IV+L++++
Sbjct: 724 -----DCALVISGDSLEVCLK-YYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTG 777
Query: 1048 VMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYS 1107
+T ++GDG NDVSMIQ +D G+G+ G+EG QA +++DF+IT+FKHL +LL+VHG Y
Sbjct: 778 KLTCAVGDGGNDVSMIQESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYK 837
Query: 1108 RLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFG-VLD 1166
R A + + +++++C + + F+S + + +I ++ +T P VF VLD
Sbjct: 838 RSAALSQFVIHRSLCISTMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFP--VFSLVLD 895
Query: 1167 KDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFT 1226
KD+ +E + PELYK + TF I ++ + YQ + L ++ + +
Sbjct: 896 KDVKSEVAMLYPELYKDLLKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVHIVA 955
Query: 1227 FGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLY 1272
T + T LL A+ ++TW V L S Y + SL++
Sbjct: 956 ISF---TSLILTELLMVALTIQTWHWLMTVAELLSLACY-IASLVF 997
Score = 169 bits (429), Expect = 1e-41
Identities = 131/459 (28%), Positives = 212/459 (46%), Gaps = 54/459 (11%)
Query: 60 EEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITM 119
E+ +RYP N KY FTFLP LF QF + NLYFL L ++P M +
Sbjct: 47 EKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYW 106
Query: 120 LPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYER-KEQTYVQKCWKDVRVGDFIQM 178
+PL VL V +I++ +E+ + + DK +N ++Y R + V+ +++VGD I +
Sbjct: 107 VPLGFVLAVTVIREAVEEIRCYVRDKEVNS---QVYSRLTARGTVKVKSSNIQVGDLIIV 163
Query: 179 KCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTI 238
+ N+ VPAD++ L +S+ NG C L T LDGET+ K R V + + + +
Sbjct: 164 EKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYV 223
Query: 239 VCEKPNNHLNKFKGYMEHPDQ---TRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKA 295
E+PN ++ F G D E+ L G T+ + VG+V+Y G E ++
Sbjct: 224 YAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAG-TVVASGTVVGVVLYTGRELRS 282
Query: 296 MLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANG 355
++N S PR K + +N G L+++ L+
Sbjct: 283 VMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA---------------------- 320
Query: 356 SFLPSALGGFYM-FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQ 414
L G +Y+ + ++L +IPISL V++++ K+ + + D +
Sbjct: 321 --LQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKI------PGTV 372
Query: 415 CRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDG 474
R+ I E LG+I Y+ +DKTGTLT+N+M+F+R + Y LDS
Sbjct: 373 VRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYG-------------LDSMD 419
Query: 475 EEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARV 513
E Q S + +QDP + +RR+ S+RV
Sbjct: 420 E--VQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRV 456
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 229 bits (584), Expect = 1e-59
Identities = 128/330 (38%), Positives = 195/330 (59%), Gaps = 22/330 (6%)
Query: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124
+Y N T+KY + TFLP NLFEQF AN YFLFL+IL +P + T++PL +
Sbjct: 28 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
Query: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYV-----QKCWKDVRVGDFIQMK 179
VL + +KD +D+ RH+ D +N R+ Q + Q+ W +V VGD I+++
Sbjct: 88 VLTITAVKDATDDYFRHKSDNQVN-------NRQSQVLINGILQQEQWMNVCVGDIIKLE 140
Query: 180 CNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIV 239
N+ V AD+LLL SS+P+G+C++ETA LDGETN+K R + S+ + F ++
Sbjct: 141 NNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVI 200
Query: 240 CEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNN 299
CE PNN L+KF G + + + + +++LLRGC +RNTE G+VI+AG +TK M N+
Sbjct: 201 CEPPNNKLDKFSGTL-YWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNS 259
Query: 300 SGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNG----TFEEHPPFDVPDANG 355
++KR+ I+R MN + + G L+ M +I A+G++IW F+ + P+D +
Sbjct: 260 GRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSA 319
Query: 356 SFLPSALGGFYMFLTMIILLQVLIPISLYV 385
F GF F + II+L ++PISLYV
Sbjct: 320 FF-----SGFLSFWSYIIILNTVVPISLYV 344
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 98.2 bits (243), Expect = 5e-20
Identities = 126/471 (26%), Positives = 198/471 (42%), Gaps = 106/471 (22%)
Query: 766 FDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMD-----LLEDPACVPDINMEKKLRKIRA 820
F+SVRK MS V+R+P G +Y+KGA +I+ L VP + K R
Sbjct: 568 FNSVRKSMSTVIRNP-NGGFRMYSKGASEIILRKCNRILDRKGEAVP---FKNKDRDDMV 623
Query: 821 RTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQ 880
RT ++ A DGLRT+CIA + DF + E S DN +E+L E
Sbjct: 624 RTV--IEPMACDGLRTICIAYR-----DFD-------DTEPSWDNENEILTE-------- 661
Query: 881 LTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYT 940
LT + GIED ++ VPD IA ++AGI + ++TGD TA IA C +L D
Sbjct: 662 LTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLC 721
Query: 941 INTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDG 1000
+ E K+F L + ++
Sbjct: 722 L-----------------EGKEFNRLIRNEK----------------------------- 735
Query: 1001 KTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKL----RVMTLSIGDG 1056
+ Q KL+K + +L + RS+P K +VK + D R + GDG
Sbjct: 736 ---GEVEQEKLDKIWPKLR------VLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
Query: 1057 ANDVSMIQAADIG--IGISGQEGMQAVMSSDFAIT--RFKHLKKLLLVHGHWCYSRLARM 1112
ND ++ AD+G +GI+G + A +SD +T F + K ++ G Y +++
Sbjct: 787 TNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKF 843
Query: 1113 VVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAE 1172
+ + L NV V + F + + + QM++ NL + L L + E
Sbjct: 844 LQFQLTVNVVAVIVAF---TGACITQDSPLKAVQMLWVNLIMDTFASL---ALATEPPTE 897
Query: 1173 TLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID 1223
+LL + G+N + + + AFYQ ++ F + + K DID
Sbjct: 898 SLL---KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDID 945
Score = 36.2 bits (82), Expect = 0.24
Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 11/104 (10%)
Query: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
F+ I +L V +P L +++ + V + D +L R L+ E +G
Sbjct: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 459
Query: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELD 471
I SDKTGTLT N+M + I G Y Q + + PK LD
Sbjct: 460 TAICSDKTGTLTMNRMTVVQAYIGGIHY-RQIPSPDVFLPKVLD 502
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 98.2 bits (243), Expect = 5e-20
Identities = 126/471 (26%), Positives = 198/471 (42%), Gaps = 106/471 (22%)
Query: 766 FDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMD-----LLEDPACVPDINMEKKLRKIRA 820
F+SVRK MS V+R+P G +Y+KGA +I+ L VP + K R
Sbjct: 568 FNSVRKSMSTVIRNP-NGGFRMYSKGASEIILRKCNRILDRKGEAVP---FKNKDRDDMV 623
Query: 821 RTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQ 880
RT ++ A DGLRT+CIA + DF + E S DN +E+L E
Sbjct: 624 RTV--IEPMACDGLRTICIAYR-----DFD-------DTEPSWDNENEILTE-------- 661
Query: 881 LTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYT 940
LT + GIED ++ VPD IA ++AGI + ++TGD TA IA C +L D
Sbjct: 662 LTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLC 721
Query: 941 INTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDG 1000
+ E K+F L + ++
Sbjct: 722 L-----------------EGKEFNRLIRNEK----------------------------- 735
Query: 1001 KTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKL----RVMTLSIGDG 1056
+ Q KL+K + +L + RS+P K +VK + D R + GDG
Sbjct: 736 ---GEVEQEKLDKIWPKLR------VLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
Query: 1057 ANDVSMIQAADIG--IGISGQEGMQAVMSSDFAIT--RFKHLKKLLLVHGHWCYSRLARM 1112
ND ++ AD+G +GI+G + A +SD +T F + K ++ G Y +++
Sbjct: 787 TNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKF 843
Query: 1113 VVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAE 1172
+ + L NV V + F + + + QM++ NL + L L + E
Sbjct: 844 LQFQLTVNVVAVIVAF---TGACITQDSPLKAVQMLWVNLIMDTFASL---ALATEPPTE 897
Query: 1173 TLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID 1223
+LL + G+N + + + AFYQ ++ F + + K DID
Sbjct: 898 SLL---KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDID 945
Score = 36.2 bits (82), Expect = 0.24
Identities = 32/104 (30%), Positives = 47/104 (45%), Gaps = 11/104 (10%)
Query: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
F+ I +L V +P L +++ + V + D +L R L+ E +G
Sbjct: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 459
Query: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELD 471
I SDKTGTLT N+M + I G Y Q + + PK LD
Sbjct: 460 TAICSDKTGTLTMNRMTVVQAYIGGIHY-RQIPSPDVFLPKVLD 502
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 82.4 bits (202), Expect = 3e-15
Identities = 117/465 (25%), Positives = 202/465 (43%), Gaps = 92/465 (19%)
Query: 766 FDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRAR---T 822
F+SVRK MS V+++ G +++KGA +I L+ + N E K+ + R R
Sbjct: 578 FNSVRKSMSTVLKNS-DGSYRIFSKGASEII---LKKCFKILSANGEAKVFRPRDRDDIV 633
Query: 823 QKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLT 882
+ ++ A +GLRT+C+A FR + + E E DN ++++ LT
Sbjct: 634 KTVIEPMASEGLRTICLA--------FRDFPA--GEPEPEWDNENDIV--------TGLT 675
Query: 883 LLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTIN 942
+ GIED ++ VPD I + AGI + ++TGD TA IA C +L+ + +
Sbjct: 676 CIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL- 734
Query: 943 TENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKT 1002
+ K F R+ ++ I E
Sbjct: 735 ---------------------------EGKDFNRRIRNEKGEIEQE-------------- 753
Query: 1003 LNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSM 1062
+++K + +L RS + T L K +I V D+ +V+ ++ GDG ND
Sbjct: 754 -------RIDKIWPKLRVLARSSPTDKHT-LVKGIIDSTVSDQRQVVAVT-GDGTNDGPA 804
Query: 1063 IQAADIG--IGISGQEGMQAVMSSDFAIT--RFKHLKKLLLVHGHWCYSRLARMVVYYLY 1118
++ AD+G +GI+G + A +SD +T F + K ++ G Y +++ + + L
Sbjct: 805 LKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLT 861
Query: 1119 KNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALP 1178
NV V + F + + + QM++ NL +L L L + E+LL L
Sbjct: 862 VNVVAVIVAF---TGACITQDSPLKAVQMLWVNLIMDTLASL---ALATEPPTESLL-LR 914
Query: 1179 ELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID 1223
+ Y G+N + + + AFYQ ++ F + + K DID
Sbjct: 915 KPY--GRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDID 957
Score = 33.1 bits (74), Expect = 2.0
Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 16/103 (15%)
Query: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
F+ + +L V +P L +++ + V + D +L R L+ E +G
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 469
Query: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKEL 470
I SDKTGTLT N+M + Y ++++ K++ P+ +
Sbjct: 470 TAICSDKTGTLTMNRMT------VVQAYINEKHYKKVPEPEAI 506
Score = 31.2 bits (69), Expect = 7.6
Identities = 15/44 (34%), Positives = 28/44 (63%), Gaps = 4/44 (9%)
Query: 169 DVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETN 212
D+ VGD Q+K +++PAD +L+ +D ++ +SL GE++
Sbjct: 209 DITVGDIAQVKYGDLLPADGILIQGND----LKIDESSLTGESD 248
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 82.4 bits (202), Expect = 3e-15
Identities = 117/465 (25%), Positives = 202/465 (43%), Gaps = 92/465 (19%)
Query: 766 FDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRAR---T 822
F+SVRK MS V+++ G +++KGA +I L+ + N E K+ + R R
Sbjct: 578 FNSVRKSMSTVLKNS-DGSYRIFSKGASEII---LKKCFKILSANGEAKVFRPRDRDDIV 633
Query: 823 QKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLT 882
+ ++ A +GLRT+C+A FR + + E E DN ++++ LT
Sbjct: 634 KTVIEPMASEGLRTICLA--------FRDFPA--GEPEPEWDNENDIV--------TGLT 675
Query: 883 LLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTIN 942
+ GIED ++ VPD I + AGI + ++TGD TA IA C +L+ + +
Sbjct: 676 CIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL- 734
Query: 943 TENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKT 1002
+ K F R+ ++ I E
Sbjct: 735 ---------------------------EGKDFNRRIRNEKGEIEQE-------------- 753
Query: 1003 LNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSM 1062
+++K + +L RS + T L K +I V D+ +V+ ++ GDG ND
Sbjct: 754 -------RIDKIWPKLRVLARSSPTDKHT-LVKGIIDSTVSDQRQVVAVT-GDGTNDGPA 804
Query: 1063 IQAADIG--IGISGQEGMQAVMSSDFAIT--RFKHLKKLLLVHGHWCYSRLARMVVYYLY 1118
++ AD+G +GI+G + A +SD +T F + K ++ G Y +++ + + L
Sbjct: 805 LKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKFLQFQLT 861
Query: 1119 KNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALP 1178
NV V + F + + + QM++ NL +L L L + E+LL L
Sbjct: 862 VNVVAVIVAF---TGACITQDSPLKAVQMLWVNLIMDTLASL---ALATEPPTESLL-LR 914
Query: 1179 ELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID 1223
+ Y G+N + + + AFYQ ++ F + + K DID
Sbjct: 915 KPY--GRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDID 957
Score = 33.1 bits (74), Expect = 2.0
Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 16/103 (15%)
Query: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
F+ + +L V +P L +++ + V + D +L R L+ E +G
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 469
Query: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKEL 470
I SDKTGTLT N+M + Y ++++ K++ P+ +
Sbjct: 470 TAICSDKTGTLTMNRMT------VVQAYINEKHYKKVPEPEAI 506
Score = 31.2 bits (69), Expect = 7.6
Identities = 15/44 (34%), Positives = 28/44 (63%), Gaps = 4/44 (9%)
Query: 169 DVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETN 212
D+ VGD Q+K +++PAD +L+ +D ++ +SL GE++
Sbjct: 209 DITVGDIAQVKYGDLLPADGILIQGND----LKIDESSLTGESD 248
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 82.4 bits (202), Expect = 3e-15
Identities = 115/471 (24%), Positives = 193/471 (40%), Gaps = 105/471 (22%)
Query: 766 FDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRAR---- 821
F+SVRK MS V+R P G +++KGA +++ C +N +LR R R
Sbjct: 576 FNSVRKSMSTVIRMP-DGGFRLFSKGASEILLK-----KCTNILNSNGELRGFRPRDRDD 629
Query: 822 -TQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQ 880
+K ++ A DGLRT+CIA + F E DN +E++
Sbjct: 630 MVRKIIEPMACDGLRTICIA-----------YRDFSAGQEPDWDNENEVV--------GD 670
Query: 881 LTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYT 940
LT + GIED ++ VP+ I + AGI + ++TGD TA IA C ++ +
Sbjct: 671 LTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLC 730
Query: 941 INTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDG 1000
+ + K F R+ ++ I E
Sbjct: 731 L----------------------------EGKEFNRRIRNEKGEIEQE------------ 750
Query: 1001 KTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRD----KLRVMTLSIGDG 1056
+L+K + +L + RS+P K +VK + D + R + GDG
Sbjct: 751 ---------RLDKVWPKLR------VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDG 795
Query: 1057 ANDVSMIQAADIG--IGISGQEGMQAVMSSDFAIT--RFKHLKKLLLVHGHWCYSRLARM 1112
ND ++ AD+G +GI+G + A +SD +T F + K ++ G Y +++
Sbjct: 796 TNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKF 852
Query: 1113 VVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAE 1172
+ + L NV V + F + + + QM++ NL + L L + E
Sbjct: 853 LQFQLTVNVVAVIVAF---TGACITQDSPLKAVQMLWVNLIMDTFASL---ALATEPPTE 906
Query: 1173 TLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID 1223
+LL L + Y G++ + + + A YQ I F + ++ DID
Sbjct: 907 SLL-LRKPY--GRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDID 954
Score = 36.2 bits (82), Expect = 0.24
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 11/104 (10%)
Query: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
F+ + +L V +P L +++ + V + D +L R L+ E +G
Sbjct: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 467
Query: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELD 471
I SDKTGTLT N+M + + +G + + A TPK LD
Sbjct: 468 TAICSDKTGTLTTNRMTVVQ-SYLGDTHYKEIPAPSALTPKILD 510
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 82.4 bits (202), Expect = 3e-15
Identities = 115/471 (24%), Positives = 193/471 (40%), Gaps = 105/471 (22%)
Query: 766 FDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRAR---- 821
F+SVRK MS V+R P G +++KGA +++ C +N +LR R R
Sbjct: 576 FNSVRKSMSTVIRMP-DGGFRLFSKGASEILLK-----KCTNILNSNGELRGFRPRDRDD 629
Query: 822 -TQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQ 880
+K ++ A DGLRT+CIA + F E DN +E++
Sbjct: 630 MVRKIIEPMACDGLRTICIA-----------YRDFSAGQEPDWDNENEVV--------GD 670
Query: 881 LTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYT 940
LT + GIED ++ VP+ I + AGI + ++TGD TA IA C ++ +
Sbjct: 671 LTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLC 730
Query: 941 INTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDG 1000
+ + K F R+ ++ I E
Sbjct: 731 L----------------------------EGKEFNRRIRNEKGEIEQE------------ 750
Query: 1001 KTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRD----KLRVMTLSIGDG 1056
+L+K + +L + RS+P K +VK + D + R + GDG
Sbjct: 751 ---------RLDKVWPKLR------VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDG 795
Query: 1057 ANDVSMIQAADIG--IGISGQEGMQAVMSSDFAIT--RFKHLKKLLLVHGHWCYSRLARM 1112
ND ++ AD+G +GI+G + A +SD +T F + K ++ G Y +++
Sbjct: 796 TNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFTSIVKAVM-WGRNVYDSISKF 852
Query: 1113 VVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAE 1172
+ + L NV V + F + + + QM++ NL + L L + E
Sbjct: 853 LQFQLTVNVVAVIVAF---TGACITQDSPLKAVQMLWVNLIMDTFASL---ALATEPPTE 906
Query: 1173 TLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID 1223
+LL L + Y G++ + + + A YQ I F + ++ DID
Sbjct: 907 SLL-LRKPY--GRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDID 954
Score = 36.2 bits (82), Expect = 0.24
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 11/104 (10%)
Query: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
F+ + +L V +P L +++ + V + D +L R L+ E +G
Sbjct: 418 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 467
Query: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELD 471
I SDKTGTLT N+M + + +G + + A TPK LD
Sbjct: 468 TAICSDKTGTLTTNRMTVVQ-SYLGDTHYKEIPAPSALTPKILD 510
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
Length = 1198
Score = 81.3 bits (199), Expect = 6e-15
Identities = 113/471 (23%), Positives = 194/471 (41%), Gaps = 105/471 (22%)
Query: 766 FDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRAR---- 821
F+SVRK MS V++ P +Y+KGA +++ C +N + R R R
Sbjct: 557 FNSVRKSMSTVIKLP-DESFRMYSKGASEIVLK-----KCCKILNGAGEPRVFRPRDRDE 610
Query: 822 -TQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQ 880
+K ++ A DGLRT+C+A + F E DN +++L N+
Sbjct: 611 MVKKVIEPMACDGLRTICVA-----------YRDFPSSPEPDWDNENDIL--------NE 651
Query: 881 LTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYT 940
LT + GIED ++ VP+ I + AGI + ++TGD TA IA C +++ +
Sbjct: 652 LTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLC 711
Query: 941 INTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDG 1000
+ + K F R+ ++ I E
Sbjct: 712 L----------------------------EGKEFNRRIRNEKGEIEQE------------ 731
Query: 1001 KTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRD----KLRVMTLSIGDG 1056
+++K + +L + RS+P K +VK + D + R + GDG
Sbjct: 732 ---------RIDKIWPKLR------VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDG 776
Query: 1057 ANDVSMIQAADIG--IGISGQEGMQAVMSSDFAIT--RFKHLKKLLLVHGHWCYSRLARM 1112
ND ++ AD+G +GI+G + A +SD +T F + K ++ G Y +++
Sbjct: 777 TNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFSSIVKAVM-WGRNVYDSISKF 833
Query: 1113 VVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAE 1172
+ + L NV V + F + + + QM++ NL + L L + E
Sbjct: 834 LQFQLTVNVVAVIVAF---TGACITQDSPLKAVQMLWVNLIMDTFASL---ALATEPPTE 887
Query: 1173 TLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID 1223
TLL L + Y G+N + + + A YQ + F + ++ K ID
Sbjct: 888 TLL-LRKPY--GRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQID 935
Score = 33.1 bits (74), Expect = 2.0
Identities = 64/314 (20%), Positives = 120/314 (38%), Gaps = 49/314 (15%)
Query: 169 DVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQ 228
++ VGD Q+K +++PAD L + +D ++ +SL GE++ ++ V K
Sbjct: 207 EIVVGDIAQVKYGDLLPADGLFIQGND----LKIDESSLTGESDQVRKSVDK-------- 254
Query: 229 FEPELFHNTIVCEKPNNHLNKFKGYMEHPDQ--TRTGFGCESLLLRGCTIRNTEMAVGIV 286
+P L T V E L G T G G E + + + A +
Sbjct: 255 -DPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAME 313
Query: 287 IY---------AGHETKAMLNNSGPRYKRSKIER-RMNID----IFFCIGILILMCLIGA 332
+ A KA ++ + K+ + + I + I ++IL+
Sbjct: 314 MQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTV 373
Query: 333 VGHSIWNGTFEEHPPFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKL 392
TF + +P+ ++ + F + +T+++ V +P L +++ +
Sbjct: 374 -------DTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLV---VAVPEGLPLAVTISLA 423
Query: 393 GQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMG 452
V + D +L R L+ E +G I SDKTGTLT N+M + +
Sbjct: 424 YSVKKMMKDNNLV----------RHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD 473
Query: 453 SEYSHQENAKRLET 466
Y + + T
Sbjct: 474 VHYKEIPDPSSINT 487
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens]
Length = 1243
Score = 81.3 bits (199), Expect = 6e-15
Identities = 113/471 (23%), Positives = 194/471 (41%), Gaps = 105/471 (22%)
Query: 766 FDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRAR---- 821
F+SVRK MS V++ P +Y+KGA +++ C +N + R R R
Sbjct: 602 FNSVRKSMSTVIKLP-DESFRMYSKGASEIVLK-----KCCKILNGAGEPRVFRPRDRDE 655
Query: 822 -TQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQ 880
+K ++ A DGLRT+C+A + F E DN +++L N+
Sbjct: 656 MVKKVIEPMACDGLRTICVA-----------YRDFPSSPEPDWDNENDIL--------NE 696
Query: 881 LTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYT 940
LT + GIED ++ VP+ I + AGI + ++TGD TA IA C +++ +
Sbjct: 697 LTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLC 756
Query: 941 INTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDG 1000
+ + K F R+ ++ I E
Sbjct: 757 L----------------------------EGKEFNRRIRNEKGEIEQE------------ 776
Query: 1001 KTLNAIFQGKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRD----KLRVMTLSIGDG 1056
+++K + +L + RS+P K +VK + D + R + GDG
Sbjct: 777 ---------RIDKIWPKLR------VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDG 821
Query: 1057 ANDVSMIQAADIG--IGISGQEGMQAVMSSDFAIT--RFKHLKKLLLVHGHWCYSRLARM 1112
ND ++ AD+G +GI+G + A +SD +T F + K ++ G Y +++
Sbjct: 822 TNDGPALKKADVGFAMGIAGTD--VAKEASDIILTDDNFSSIVKAVM-WGRNVYDSISKF 878
Query: 1113 VVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAE 1172
+ + L NV V + F + + + QM++ NL + L L + E
Sbjct: 879 LQFQLTVNVVAVIVAF---TGACITQDSPLKAVQMLWVNLIMDTFASL---ALATEPPTE 932
Query: 1173 TLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDID 1223
TLL L + Y G+N + + + A YQ + F + ++ K ID
Sbjct: 933 TLL-LRKPY--GRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQID 980
Score = 32.7 bits (73), Expect = 2.6
Identities = 25/99 (25%), Positives = 42/99 (42%), Gaps = 10/99 (10%)
Query: 368 FLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQI 427
F+ + +L V +P L +++ + V + D +L R L+ E +G
Sbjct: 444 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLV----------RHLDACETMGNA 493
Query: 428 QYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLET 466
I SDKTGTLT N+M + + Y + + T
Sbjct: 494 TAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINT 532
>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
Length = 1175
Score = 75.1 bits (183), Expect = 5e-13
Identities = 84/320 (26%), Positives = 135/320 (42%), Gaps = 45/320 (14%)
Query: 759 SLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKI 818
S+L F S +RMSVVV P + Y KG+ ++ L +P VP
Sbjct: 618 SVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLC-NPETVP----------- 665
Query: 819 RARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLE 878
+ L Y G R + +A K + SL+ +L +T +E
Sbjct: 666 -TDFAQMLQSYTAAGYRVVALASKPLP-------------TVPSLEAAQQLTRDT---VE 708
Query: 879 NQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTV 938
L+LLG + + L+ I LR I+ ++TGD +TAV +A C ++ + +
Sbjct: 709 GDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHL 768
Query: 939 YTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVI 998
++ + E + +LE F ++ P + G + P + S T E L +
Sbjct: 769 IIVHATHPERGQP---ASLE----FLPMESP-TAVNGVKDPDQAASYTVEPDPRSRHLAL 820
Query: 999 DGKTLNAIFQ--GKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDG 1056
G T I + KL K L + + R P QK+ +V ++ KL+ GDG
Sbjct: 821 SGPTFGIIVKHFPKLLPKVL-----VQGTVFARMAPEQKTELVCELQ-KLQYCVGMCGDG 874
Query: 1057 ANDVSMIQAADIGIGISGQE 1076
AND ++AAD+GI +S E
Sbjct: 875 ANDCGALKAADVGISLSQAE 894
>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
Length = 1180
Score = 75.1 bits (183), Expect = 5e-13
Identities = 84/320 (26%), Positives = 135/320 (42%), Gaps = 45/320 (14%)
Query: 759 SLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKI 818
S+L F S +RMSVVV P + Y KG+ ++ L +P VP
Sbjct: 623 SVLHRFPFSSALQRMSVVVAWPGATQPEAYVKGSPELVAGLC-NPETVP----------- 670
Query: 819 RARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLE 878
+ L Y G R + +A K + SL+ +L +T +E
Sbjct: 671 -TDFAQMLQSYTAAGYRVVALASKPLP-------------TVPSLEAAQQLTRDT---VE 713
Query: 879 NQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTV 938
L+LLG + + L+ I LR I+ ++TGD +TAV +A C ++ + +
Sbjct: 714 GDLSLLGLLVMRNLLKPQTTPVIQALRRTRIRAVMVTGDNLQTAVTVARGCGMVAPQEHL 773
Query: 939 YTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVI 998
++ + E + +LE F ++ P + G + P + S T E L +
Sbjct: 774 IIVHATHPERGQP---ASLE----FLPMESP-TAVNGVKDPDQAASYTVEPDPRSRHLAL 825
Query: 999 DGKTLNAIFQ--GKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDG 1056
G T I + KL K L + + R P QK+ +V ++ KL+ GDG
Sbjct: 826 SGPTFGIIVKHFPKLLPKVL-----VQGTVFARMAPEQKTELVCELQ-KLQYCVGMCGDG 879
Query: 1057 ANDVSMIQAADIGIGISGQE 1076
AND ++AAD+GI +S E
Sbjct: 880 ANDCGALKAADVGISLSQAE 899
>gi|66730421 ATPase type 13A5 [Homo sapiens]
Length = 1218
Score = 74.7 bits (182), Expect = 6e-13
Identities = 81/322 (25%), Positives = 133/322 (41%), Gaps = 43/322 (13%)
Query: 761 LCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRA 820
LC F S +RMSV+ + VY KGA ++ VP N ++LR
Sbjct: 595 LCQFPFSSSLQRMSVIAQLAGENHFHVYMKGAPEMVARFCRSET-VPK-NFPQELRS--- 649
Query: 821 RTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQ 880
Y G R + +A K + + N E+ + +E++
Sbjct: 650 --------YTVQGFRVIALAHKTLK-----------------MGNLSEVEHLAREKVESE 684
Query: 881 LTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYT 940
LT LG +E+RL++ + L EA I+ ++TGD +TA+ +A + ++ V
Sbjct: 685 LTFLGLLIMENRLKKETKLVLKELSEARIRTVMITGDNLQTAITVAKNSEMIPPGSQVII 744
Query: 941 INTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDG 1000
+ + E E + +L + +E ++++ S TP + A + G
Sbjct: 745 VEADEPE--EFVPASVTWQLVENQETGPGKKEIYMHTGNSSTPRGEGGSCYHFA---MSG 799
Query: 1001 KTLNAIFQ--GKLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGAN 1058
K+ IFQ L K L + R +P QKS +++ + KL GDGAN
Sbjct: 800 KSYQVIFQHFNSLLPKIL-----VNGTVFARMSPGQKSSLIEEFQ-KLNYYVGMCGDGAN 853
Query: 1059 DVSMIQAADIGIGISGQEGMQA 1080
D ++AA GI +S QE A
Sbjct: 854 DCGALKAAHAGISLSEQEASVA 875
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 70.5 bits (171), Expect = 1e-11
Identities = 100/425 (23%), Positives = 171/425 (40%), Gaps = 72/425 (16%)
Query: 741 RTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLL 800
RT QV V ++L F S +RM+V+V+ + G+ + + KGA +
Sbjct: 583 RTASQVPVE-------GIAILHQFPFSSALQRMTVIVQE-MGGDRLAFMKGAPERVASFC 634
Query: 801 EDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAE 860
+ P VP + + L +Y G R + +A K
Sbjct: 635 Q-PETVPTSFVSE------------LQIYTTQGFRVIALAYK------------------ 663
Query: 861 ASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQE 920
L+N T + +E+ L LG +E+RL+E + L A I+ ++TGD +
Sbjct: 664 -KLENDHHATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQ 722
Query: 921 TAVNIAHSCRLLNQTDTVYTIN-TENQETCESILNCALEELKQFRELQKPDRKLFGFRLP 979
TA+ +A +++++ V I E + + ++ L E K+ D +
Sbjct: 723 TAITVARKSGMVSESQKVILIEANETTGSSSASISWTLVEEKKHIMYGNQDNYI------ 776
Query: 980 SKTPSITSEAVVPEAGLVIDGKTLNAIFQ--GKLEKKFLELTQYCRSVLCCRSTPLQKSM 1037
+ ++ + + GK+ + I Q L K L + R +P QKS
Sbjct: 777 NIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPKIL-----INGTIFARMSPGQKSS 831
Query: 1038 IVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQA--VMSSDFAITRFKHLK 1095
+V+ + KL GDGAND ++ A +GI +S QE A S I HL
Sbjct: 832 LVEEFQ-KLDYFVGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLI 890
Query: 1096 K---LLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNL 1152
K LV + +A LY + YV +L Y + ++++ +Y Q +F +L
Sbjct: 891 KEGRAALVTSFCMFKYMA------LYSMIQYVGVLLLY-----WETNSLSNY-QFLFQDL 938
Query: 1153 FFTSL 1157
T+L
Sbjct: 939 AITTL 943
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,217,507
Number of Sequences: 37866
Number of extensions: 2480389
Number of successful extensions: 7423
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 7000
Number of HSP's gapped (non-prelim): 308
length of query: 1461
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1346
effective length of database: 13,892,928
effective search space: 18699881088
effective search space used: 18699881088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.