Guide to the Human Genome
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Search of human proteins with 149363676

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149363676 hypothetical protein LOC404770 [Homo sapiens]
         (182 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149363676 hypothetical protein LOC404770 [Homo sapiens]            384   e-107
gi|223468617 family with sequence similarity 75, member C1 [Homo...   233   5e-62
gi|223633941 hypothetical protein LOC389730 [Homo sapiens]            219   1e-57
gi|153791826 hypothetical protein LOC26165 [Homo sapiens]             219   1e-57
gi|133892686 hypothetical protein LOC727830 [Homo sapiens]            218   2e-57
gi|146231958 hypothetical protein LOC647060 [Homo sapiens]            218   3e-57
gi|169174618 PREDICTED: family with sequence similarity 75, memb...   215   1e-56
gi|239743732 PREDICTED: family with sequence similarity 75, memb...   215   1e-56
gi|165377334 hypothetical protein LOC727905 [Homo sapiens]            215   1e-56
gi|91206406 hypothetical protein LOC642265 [Homo sapiens]             214   3e-56
gi|155029550 chromosome 9 open reading frame 79 [Homo sapiens]         69   3e-12
gi|48717285 hypothetical protein LOC389763 [Homo sapiens]              49   3e-06
gi|223633944 hypothetical protein LOC389762 [Homo sapiens]             46   2e-05
gi|223671858 hypothetical protein LOC389761 [Homo sapiens]             46   2e-05
gi|169168458 PREDICTED: hypothetical protein [Homo sapiens]            44   1e-04
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       41   6e-04
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       39   0.002
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         39   0.002
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]         39   0.003
gi|239742749 PREDICTED: hypothetical protein XP_002342626 [Homo ...    38   0.004
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           37   0.009
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           37   0.009
gi|109240536 DC-STAMP domain containing 2 [Homo sapiens]               37   0.012
gi|214831495 hypothetical protein LOC285679 [Homo sapiens]             37   0.012
gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]                       36   0.021
gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]                       36   0.021
gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]                       36   0.021
gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]                       36   0.021
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]       36   0.021
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    35   0.027

>gi|149363676 hypothetical protein LOC404770 [Homo sapiens]
          Length = 182

 Score =  384 bits (987), Expect = e-107
 Identities = 182/182 (100%), Positives = 182/182 (100%)

Query: 1   MKPWWARDWALPSRGQCVCPGETNACLDAERACRECPRGLEETWDLLSQLQSLLGTHLDK 60
           MKPWWARDWALPSRGQCVCPGETNACLDAERACRECPRGLEETWDLLSQLQSLLGTHLDK
Sbjct: 1   MKPWWARDWALPSRGQCVCPGETNACLDAERACRECPRGLEETWDLLSQLQSLLGTHLDK 60

Query: 61  GDFGQLSGPEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSP 120
           GDFGQLSGPEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSP
Sbjct: 61  GDFGQLSGPEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSP 120

Query: 121 GPMTTSVSSLSASQPPEPSLLLERPSPKPPALFLTHHTPLILWPALLLLQKTSLLLPCGT 180
           GPMTTSVSSLSASQPPEPSLLLERPSPKPPALFLTHHTPLILWPALLLLQKTSLLLPCGT
Sbjct: 121 GPMTTSVSSLSASQPPEPSLLLERPSPKPPALFLTHHTPLILWPALLLLQKTSLLLPCGT 180

Query: 181 PL 182
           PL
Sbjct: 181 PL 182


>gi|223468617 family with sequence similarity 75, member C1 [Homo
           sapiens]
          Length = 1188

 Score =  233 bits (595), Expect = 5e-62
 Identities = 115/130 (88%), Positives = 119/130 (91%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RACRECPRGLEETWDLLSQLQSLLG HL+KGDFGQLSGP+PPGEVGKR PDGASRSS EP
Sbjct: 94  RACRECPRGLEETWDLLSQLQSLLGPHLEKGDFGQLSGPDPPGEVGKRTPDGASRSSHEP 153

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+  LASPDPR KHPQDLASTP PGPMTTSVSSLSASQPPEPSLLLERPSP+PP
Sbjct: 154 MEDAAPIVSPLASPDPRTKHPQDLASTPPPGPMTTSVSSLSASQPPEPSLLLERPSPEPP 213

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 214 ALFPHPPHTP 223


>gi|223633941 hypothetical protein LOC389730 [Homo sapiens]
          Length = 1343

 Score =  219 bits (557), Expect = 1e-57
 Identities = 111/130 (85%), Positives = 117/130 (90%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RA RECPRGLEET DLLSQLQSLLG HLDKGDFGQLSGP+PPGEVG+RAPDGAS+SS EP
Sbjct: 82  RAGRECPRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEP 141

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+  LASPDP+ KHPQDLASTPSPGPMTTSVSSLSASQPPEPSL LE PSP+PP
Sbjct: 142 MEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPP 201

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 202 ALFPHPPHTP 211


>gi|153791826 hypothetical protein LOC26165 [Homo sapiens]
          Length = 1347

 Score =  219 bits (557), Expect = 1e-57
 Identities = 111/130 (85%), Positives = 117/130 (90%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RA RECPRGLEET DLLSQLQSLLG HLDKGDFGQLSGP+PPGEVG+RAPDGAS+SS EP
Sbjct: 82  RAGRECPRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEP 141

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+  LASPDP+ KHPQDLASTPSPGPMTTSVSSLSASQPPEPSL LE PSP+PP
Sbjct: 142 MEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPP 201

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 202 ALFPHPPHTP 211


>gi|133892686 hypothetical protein LOC727830 [Homo sapiens]
          Length = 1347

 Score =  218 bits (555), Expect = 2e-57
 Identities = 111/130 (85%), Positives = 117/130 (90%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RA REC RGLEET DLLSQLQSLLG HLDKGDFGQLSGP+PPGEVG+RAPDGAS+SS EP
Sbjct: 82  RAGRECRRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEP 141

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+ LLASPDP+ KHPQDLASTPSPGPMTTSVSSLSASQPPEPSL LE PSP+PP
Sbjct: 142 MEDAAPILSLLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPP 201

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 202 ALFPHPPHTP 211


>gi|146231958 hypothetical protein LOC647060 [Homo sapiens]
          Length = 1347

 Score =  218 bits (554), Expect = 3e-57
 Identities = 110/130 (84%), Positives = 117/130 (90%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RA RECPRGL+ET DLLSQLQSLLG HLDKGDFGQLSGP+PPGEVG+RAPDGAS+SS EP
Sbjct: 82  RAGRECPRGLQETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEP 141

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+  LASPDP+ KHPQDLASTPSPGPMTTSVSSLSASQPPEPSL LE PSP+PP
Sbjct: 142 MEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPP 201

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 202 ALFPHPPHTP 211


>gi|169174618 PREDICTED: family with sequence similarity 75, member
           A4 isoform 2 [Homo sapiens]
          Length = 1272

 Score =  215 bits (548), Expect = 1e-56
 Identities = 110/130 (84%), Positives = 116/130 (89%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RA REC RGLEET DLLSQLQSLLG HLDKGDFGQLSGP+PPGEVG+RAPDGAS+SS EP
Sbjct: 7   RAGRECRRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEP 66

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+  LASPDP+ KHPQDLASTPSPGPMTTSVSSLSASQPPEPSL LE PSP+PP
Sbjct: 67  MEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPP 126

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 127 ALFPHPPHTP 136


>gi|239743732 PREDICTED: family with sequence similarity 75, member
           A4 isoform 1 [Homo sapiens]
          Length = 1361

 Score =  215 bits (548), Expect = 1e-56
 Identities = 110/130 (84%), Positives = 116/130 (89%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RA REC RGLEET DLLSQLQSLLG HLDKGDFGQLSGP+PPGEVG+RAPDGAS+SS EP
Sbjct: 96  RAGRECRRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEP 155

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+  LASPDP+ KHPQDLASTPSPGPMTTSVSSLSASQPPEPSL LE PSP+PP
Sbjct: 156 MEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPP 215

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 216 ALFPHPPHTP 225


>gi|165377334 hypothetical protein LOC727905 [Homo sapiens]
          Length = 1347

 Score =  215 bits (548), Expect = 1e-56
 Identities = 110/130 (84%), Positives = 116/130 (89%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RA REC RGLEET DLLSQLQSLLG HLDKGDFGQLSGP+PPGEVG+RAPDGAS+SS EP
Sbjct: 82  RAGRECRRGLEETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEP 141

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+  LASPDP+ KHPQDLASTPSPGPMTTSVSSLSASQPPEPSL LE PSP+PP
Sbjct: 142 MEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPP 201

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 202 ALFPHPPHTP 211


>gi|91206406 hypothetical protein LOC642265 [Homo sapiens]
          Length = 1347

 Score =  214 bits (545), Expect = 3e-56
 Identities = 109/130 (83%), Positives = 116/130 (89%), Gaps = 1/130 (0%)

Query: 31  RACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRSSLEP 90
           RA REC RGL+ET DLLSQLQSLLG HLDKGDFGQLSGP+PPGEVG+RAPDGAS+SS EP
Sbjct: 82  RAGRECRRGLQETSDLLSQLQSLLGPHLDKGDFGQLSGPDPPGEVGERAPDGASQSSHEP 141

Query: 91  MEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
           MEDAAPI+  LASPDP+ KHPQDLASTPSPGPMTTSVSSLSASQPPEPSL LE PSP+PP
Sbjct: 142 MEDAAPILSPLASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLPLEHPSPEPP 201

Query: 151 ALF-LTHHTP 159
           ALF    HTP
Sbjct: 202 ALFPHPPHTP 211


>gi|155029550 chromosome 9 open reading frame 79 [Homo sapiens]
          Length = 1445

 Score = 68.6 bits (166), Expect = 3e-12
 Identities = 54/132 (40%), Positives = 70/132 (53%), Gaps = 11/132 (8%)

Query: 27  LDAERACRECPRGLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRS 86
           + A +ACR   R LEET DL   L+S L     +G      G +P G+V K  P  A + 
Sbjct: 117 ISALKACRILLRELEETRDLNYLLESHLRKLAGEGSSHLPLGGDPLGDVCKPVPAKAHQP 176

Query: 87  SLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSV-----SSLSASQPPEPSLL 141
             + M+D +P    L+ P P    P  LAST SPGPMT S      S+LSAS PPEP L 
Sbjct: 177 HGKCMQDPSPA--SLSPPAP----PAPLASTLSPGPMTFSEPFGPHSTLSASGPPEPLLP 230

Query: 142 LERPSPKPPALF 153
           L+ P+ +P  +F
Sbjct: 231 LKCPATQPHVVF 242



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 9/70 (12%)

Query: 92  EDAAPIIYLLASPDPRIKH--PQDLASTPSPGPMTTSVSSLSASQPPEPSLLLER----- 144
           E  A  +++  +P  +  H  P D AST  PG      SS  +  PP+P  + +      
Sbjct: 449 ESLATTVWVSRNPSSQNAHSVPLDKASTSLPGEPEVEASSQLSQAPPQPHHMAQPQHFTP 508

Query: 145 --PSPKPPAL 152
             P  +PP L
Sbjct: 509 AWPQSQPPPL 518


>gi|48717285 hypothetical protein LOC389763 [Homo sapiens]
          Length = 1576

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 48/136 (35%), Positives = 58/136 (42%), Gaps = 29/136 (21%)

Query: 41  EETWDLLSQLQSL--------LGTHLDKGDFGQLSGPEPPGEVGKRAP-DGASRSSLEPM 91
           EE   LLS L+S          G H D   F +L  P+P   V KRA  D     S E +
Sbjct: 90  EEERKLLSLLKSFGPPVSCSPRGQHHDTNHFRRLLCPDPVCRVCKRATADIQQLLSWESL 149

Query: 92  EDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPPA 151
           +DAAP +  LAS     +    LASTPS             + PPE  +L  RP   PP 
Sbjct: 150 KDAAPSVSPLASSASATESSFTLASTPS-------------ATPPEDLILSPRPKASPP- 195

Query: 152 LFLTHHTPLILWPALL 167
                  PLIL P L+
Sbjct: 196 ------PPLILSPDLI 205


>gi|223633944 hypothetical protein LOC389762 [Homo sapiens]
          Length = 917

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 42/117 (35%), Positives = 51/117 (43%), Gaps = 21/117 (17%)

Query: 52  SLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRS-SLEPMEDAAPIIYLLASPDPRIKH 110
           S LG H D   F +L  P+P   V  RA     R  S E ++DAAP +  LAS     + 
Sbjct: 106 SPLGQHHDTTLFRRLLCPDPVCRVCNRATADIQRLLSWESLKDAAPSVSPLASSASGAES 165

Query: 111 PQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPPALFLTHHTPLILWPALL 167
              LASTPS             +  PE  +L  RP P PP        PLIL P L+
Sbjct: 166 SFTLASTPS-------------ATTPEDLILSSRPKPSPP-------PPLILSPDLI 202


>gi|223671858 hypothetical protein LOC389761 [Homo sapiens]
          Length = 917

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 42/117 (35%), Positives = 51/117 (43%), Gaps = 21/117 (17%)

Query: 52  SLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRS-SLEPMEDAAPIIYLLASPDPRIKH 110
           S LG H D   F +L  P+P   V  RA     R  S E ++DAAP +  LAS     + 
Sbjct: 106 SPLGQHHDTTLFRRLLCPDPVCRVCNRATADIQRLLSWESLKDAAPSVSPLASSASGAES 165

Query: 111 PQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPPALFLTHHTPLILWPALL 167
              LASTPS             +  PE  +L  RP P PP        PLIL P L+
Sbjct: 166 SFTLASTPS-------------ATTPEDLILSSRPKPSPP-------PPLILSPDLI 202


>gi|169168458 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 353

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 14/107 (13%)

Query: 57  HLDKGDFGQLS------GPEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLAS-PDPRIK 109
           H  +G  G+ S       P  P       P    ++S+E +   + +    AS P   +K
Sbjct: 146 HRPRGGRGKASPTSFHVSPRAPPAPLASMPSSVPKTSIESLGSPSSLSSSQASEPLCPLK 205

Query: 110 HPQDL--ASTPSPGPMTTS-----VSSLSASQPPEPSLLLERPSPKP 149
           HP     AST SP P +++     +SSLS+SQPPEP   L+ PS KP
Sbjct: 206 HPSHRPPASTLSPNPTSSTESLGYLSSLSSSQPPEPLRPLKHPSHKP 252



 Score = 38.1 bits (87), Expect = 0.004
 Identities = 34/89 (38%), Positives = 43/89 (48%), Gaps = 10/89 (11%)

Query: 72  PGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTT-----S 126
           PG V K AP    R        A+P  + ++   P    P  LAS PS  P T+     S
Sbjct: 134 PGPVYKPAPARNHRPR-GGRGKASPTSFHVSPRAP----PAPLASMPSSVPKTSIESLGS 188

Query: 127 VSSLSASQPPEPSLLLERPSPKPPALFLT 155
            SSLS+SQ  EP   L+ PS +PPA  L+
Sbjct: 189 PSSLSSSQASEPLCPLKHPSHRPPASTLS 217


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 8/97 (8%)

Query: 71  PPGEVGKRAPDGASRSSLEPMEDAAPI-IYLLASPDP--RIKHPQDLASTPSPGPMTTSV 127
           PP       P  +     +PM   +   + +L+SP P  +++ PQ +   P P P     
Sbjct: 402 PPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQP 461

Query: 128 SS-----LSASQPPEPSLLLERPSPKPPALFLTHHTP 159
           SS     +S+   P PS  L  PSP+P    +T  TP
Sbjct: 462 SSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTP 498



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 11/74 (14%)

Query: 69  PEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPR-------IKHPQDLASTPSPG 121
           P+P  + G+ +    S  S  P    +     L SP P+        + PQ+  S PSPG
Sbjct: 452 PQPSPQPGQPSSQPNSNVSSGPAPSPSSF---LPSPSPQPSQSPVTARTPQNF-SVPSPG 507

Query: 122 PMTTSVSSLSASQP 135
           P+ T V+  S   P
Sbjct: 508 PLNTPVNPSSVMSP 521


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 7/67 (10%)

Query: 100 LLASPDP--RIKHPQDLASTPSPGPMTTSVSS-----LSASQPPEPSLLLERPSPKPPAL 152
           +L+SP P  +++ PQ +   P P P     SS     +S+   P PS  L  PSP+P   
Sbjct: 392 MLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQS 451

Query: 153 FLTHHTP 159
            +T  TP
Sbjct: 452 PVTARTP 458



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 11/74 (14%)

Query: 69  PEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPR-------IKHPQDLASTPSPG 121
           P+P  + G+ +    S  S  P    +     L SP P+        + PQ+  S PSPG
Sbjct: 412 PQPSPQPGQPSSQPNSNVSSGPAPSPSSF---LPSPSPQPSQSPVTARTPQNF-SVPSPG 467

Query: 122 PMTTSVSSLSASQP 135
           P+ T V+  S   P
Sbjct: 468 PLNTPVNPSSVMSP 481


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 38.9 bits (89), Expect = 0.002
 Identities = 34/103 (33%), Positives = 46/103 (44%), Gaps = 20/103 (19%)

Query: 69  PEPPGEVGKRAPD----GASRSSLEPME-DAAPIIYLLASP--DPRIKHPQDLASTPSPG 121
           P PP  +   AP      A RSSL P +  + P  +  +SP  DP + H  D A TP P 
Sbjct: 214 PPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSD-ALTPPPL 272

Query: 122 PMTTSVSSLSASQPPEPSLLLERPSPKPPALFLTHHTPLILWP 164
           P + ++       P  P      P+ +PP    T H PL+L P
Sbjct: 273 PPSNNL-------PAHPG-----PASQPPVSSATMHLPLVLGP 303



 Score = 30.0 bits (66), Expect = 1.1
 Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 14/115 (12%)

Query: 46  LLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRA-PDGASRSSLEPMEDAAPIIYLLAS- 103
           LL  L SL  +        Q  GP   G++G +  P G +   L   E ++P+  LL S 
Sbjct: 744 LLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLS--EASSPLACLLQSL 801

Query: 104 ------PDPRIKHPQDLASTPSPGPMTTSVSSLS----ASQPPEPSLLLERPSPK 148
                 P+     P+  AS   P P    +S+L+    +  PP P LL  R S K
Sbjct: 802 QIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGK 856



 Score = 29.6 bits (65), Expect = 1.5
 Identities = 31/105 (29%), Positives = 46/105 (43%), Gaps = 25/105 (23%)

Query: 71  PPGEVGKRAPDGASRSSLEPME---DAAPIIY----------------LLASPDPRIKHP 111
           P    G+ + +GA   S EP     D +P+++                L A+ DP    P
Sbjct: 633 PTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTP 692

Query: 112 QD--LASTPSPGPMTTSVSSLSASQPPEPSLLLERP--SPKPPAL 152
               + S P PGP T+SV+  +A+  P  S L + P  S +PP L
Sbjct: 693 PQPCVLSAPQPGPPTSSVT--TATTDPGASSLGKAPSNSGRPPQL 735



 Score = 27.7 bits (60), Expect = 5.7
 Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 6/53 (11%)

Query: 86  SSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEP 138
           S   P E A+P ++   SP P    P      P   P TT ++    S PPEP
Sbjct: 122 SHSSPGEGASPQMFHTVSPGPPSARP------PCRVPPTTPLNGGPGSLPPEP 168



 Score = 26.9 bits (58), Expect = 9.7
 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 104 PDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPPALFLTHHTPLI 161
           P+P +  P       +PG        +++  PP PS LL  PS  PP+  L    PL+
Sbjct: 573 PEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPS-APPSNLLASFLPLL 629


>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
          Length = 931

 Score = 38.5 bits (88), Expect = 0.003
 Identities = 33/109 (30%), Positives = 43/109 (39%), Gaps = 11/109 (10%)

Query: 45  DLLSQLQSLLGTHLDKGDFGQLSGPEPPG---EVGKRAPDGASRSSLEPMEDAAPIIYLL 101
           DL   LQ L GT         L   EPPG    + ++     + SS + M+D   I+   
Sbjct: 705 DLEHPLQPLFGTPTS------LLKKEPPGYEEAMSQQPKQQENGSSSQQMDDLFDILIQS 758

Query: 102 ASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPP 150
                  K P  L     P P T   S L+A   P PS  L + +P PP
Sbjct: 759 GEISADFKEPPSLPGKEKPSPKTVCGSPLAAQ--PSPSAELPQAAPPPP 805


>gi|239742749 PREDICTED: hypothetical protein XP_002342626 [Homo
           sapiens]
          Length = 277

 Score = 38.1 bits (87), Expect = 0.004
 Identities = 34/89 (38%), Positives = 43/89 (48%), Gaps = 10/89 (11%)

Query: 72  PGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTT-----S 126
           PG V K AP    R        A+P  + ++   P    P  LAS PS  P T+     S
Sbjct: 134 PGPVYKPAPARNHRPR-GGRGKASPTSFHVSPRAP----PAPLASMPSSVPKTSIESLGS 188

Query: 127 VSSLSASQPPEPSLLLERPSPKPPALFLT 155
            SSLS+SQ  EP   L+ PS +PPA  L+
Sbjct: 189 PSSLSSSQASEPLCPLKHPSHRPPASTLS 217


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 7/70 (10%)

Query: 90  PMEDAAPIIYL---LASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQP--PEPSLLLER 144
           P   A P+  L   L++P P +  P   A    PGP  T V  LS   P  P PS+ LE 
Sbjct: 406 PGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMGLEP 465

Query: 145 PS--PKPPAL 152
           P   P+PP +
Sbjct: 466 PQEVPEPPVM 475



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 5/93 (5%)

Query: 69   PEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVS 128
            P  P E     P+     S      A P  Y +++ DP +   +   + P P P   S  
Sbjct: 1200 PSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSI 1259

Query: 129  SLSASQPPEPSLLLERPS--PKPPALFLTHHTP 159
            +L+   P E +++ E     P+ P   +   TP
Sbjct: 1260 TLT---PVESAVVAEEHEVVPERPVTCMVSETP 1289


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 7/70 (10%)

Query: 90  PMEDAAPIIYL---LASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQP--PEPSLLLER 144
           P   A P+  L   L++P P +  P   A    PGP  T V  LS   P  P PS+ LE 
Sbjct: 406 PGPSATPVPELPGPLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMGLEP 465

Query: 145 PS--PKPPAL 152
           P   P+PP +
Sbjct: 466 PQEVPEPPVM 475



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 22/93 (23%), Positives = 36/93 (38%), Gaps = 5/93 (5%)

Query: 69   PEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVS 128
            P  P E     P+     S      A P  Y +++ DP +   +   + P P P   S  
Sbjct: 1200 PSSPSEESVSQPEPPVSQSEISEPSAVPTDYSVSASDPSVLVSEAAVTVPEPPPEPESSI 1259

Query: 129  SLSASQPPEPSLLLERPS--PKPPALFLTHHTP 159
            +L+   P E +++ E     P+ P   +   TP
Sbjct: 1260 TLT---PVESAVVAEEHEVVPERPVTCMVSETP 1289


>gi|109240536 DC-STAMP domain containing 2 [Homo sapiens]
          Length = 773

 Score = 36.6 bits (83), Expect = 0.012
 Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 26/116 (22%)

Query: 41  EETWDLLSQLQSLLGTHL------DKGDFGQLSGPEPPGEVGKRAPDGASRSSLEPMEDA 94
           E+ W L  QLQ +LG  L      +  D  +  GP+              +   +P+ +A
Sbjct: 676 EQAWLLQQQLQEVLGRSLSMESTSESSDLDEEKGPQQ------------RKHGQQPLPEA 723

Query: 95  APIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQP--PEPSLLLERPSPK 148
              + +L SP+P    P + +S     P   S  S+  S P  P+PS     P PK
Sbjct: 724 HQPVSILTSPEPH--RPPETSSATKGAPTPASEPSVPLSPPSLPDPS----HPPPK 773


>gi|214831495 hypothetical protein LOC285679 [Homo sapiens]
          Length = 277

 Score = 36.6 bits (83), Expect = 0.012
 Identities = 23/47 (48%), Positives = 29/47 (61%), Gaps = 5/47 (10%)

Query: 114 LASTPSPGPMTT-----SVSSLSASQPPEPSLLLERPSPKPPALFLT 155
           LAS PS  P T+     S SSLS+S+P EP   L+ PS +PPA  L+
Sbjct: 171 LASMPSSVPKTSVESLGSPSSLSSSKPREPLCPLKHPSHQPPASTLS 217


>gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]
          Length = 844

 Score = 35.8 bits (81), Expect = 0.021
 Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 3/44 (6%)

Query: 79  APDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGP 122
           +P+ A   SL P   AAPI Y LA   P ++HP      P PGP
Sbjct: 616 SPNSAHAVSLPP---AAPISYRLAEQQPLLRHPAPPGPGPGPGP 656


>gi|7669532 neuregulin 2 isoform 4 [Homo sapiens]
          Length = 852

 Score = 35.8 bits (81), Expect = 0.021
 Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 3/44 (6%)

Query: 79  APDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGP 122
           +P+ A   SL P   AAPI Y LA   P ++HP      P PGP
Sbjct: 624 SPNSAHAVSLPP---AAPISYRLAEQQPLLRHPAPPGPGPGPGP 664


>gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]
          Length = 858

 Score = 35.8 bits (81), Expect = 0.021
 Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 3/44 (6%)

Query: 79  APDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGP 122
           +P+ A   SL P   AAPI Y LA   P ++HP      P PGP
Sbjct: 630 SPNSAHAVSLPP---AAPISYRLAEQQPLLRHPAPPGPGPGPGP 670


>gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]
          Length = 850

 Score = 35.8 bits (81), Expect = 0.021
 Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 3/44 (6%)

Query: 79  APDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGP 122
           +P+ A   SL P   AAPI Y LA   P ++HP      P PGP
Sbjct: 622 SPNSAHAVSLPP---AAPISYRLAEQQPLLRHPAPPGPGPGPGP 662


>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
          Length = 981

 Score = 35.8 bits (81), Expect = 0.021
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 19/134 (14%)

Query: 29  AERACRECPR--GLEETWDLLSQLQSLLGTHLDKGDFGQLSGPEPPGEVGKRAPDGASRS 86
           AE    E P+  G E +W++ S          D  D     GP+P       APD  S+ 
Sbjct: 281 AEELPVETPKRAGAEVSWEVSSPGPP--PKQADLPDAKDSPGPQPTDPPASEAPDRPSKP 338

Query: 87  SLEPMEDAAPIIYLLASPDPRIKHPQDLASTPS---PGP------MTTSVSSLSASQPPE 137
               M  A PI     SP  R++   +   TP    PGP      +  + S + A QP E
Sbjct: 339 ERAAMNGADPI-----SPQ-RVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDE 392

Query: 138 PSLLLERPSPKPPA 151
                 RP   PPA
Sbjct: 393 AEEWPGRPQSHPPA 406


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 35.4 bits (80), Expect = 0.027
 Identities = 30/97 (30%), Positives = 39/97 (40%), Gaps = 10/97 (10%)

Query: 67  SGPEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTS 126
           S P+P G    R P         P +DAAP +  L+S       P    + P P P   +
Sbjct: 270 SQPKPKGLQALRPPQVTP-----PRKDAAPALGPLSSSPLATPSPSGTKARPVP-PPDNA 323

Query: 127 VSSLSASQPPEPSLL----LERPSPKPPALFLTHHTP 159
            + L A+ PP P L     L  PSP  P    T  +P
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360



 Score = 32.3 bits (72), Expect = 0.23
 Identities = 23/87 (26%), Positives = 37/87 (42%), Gaps = 2/87 (2%)

Query: 68  GPEPPGEVGKRAPDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLA-STPSPGPMTTS 126
           GP     +   +P G     + P ++AA  +     P P +  P  LA  +PS  P   +
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQT 356

Query: 127 VSSLSASQPPE-PSLLLERPSPKPPAL 152
           + S  A+ P + P  +   P   PP+L
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSL 383



 Score = 30.4 bits (67), Expect = 0.88
 Identities = 28/90 (31%), Positives = 38/90 (42%), Gaps = 11/90 (12%)

Query: 71  PPGEVGKRAPDGASRSSLE--PMEDAAPIIYLLASPDPRIKHPQDLASTP---SPGPMTT 125
           P      +AP   +   L+  P   A+P +   A+P P+   P  LA+ P    P P  +
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA--PPPLAAPPLQVPPSPPAS 744

Query: 126 SVSSLSASQPPEPSLLLERP----SPKPPA 151
              S SA+ PP    LL  P     P PPA
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPA 774



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 1/73 (1%)

Query: 80  PDGASRSSLEPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPS 139
           P   +   LE +   AP     AS      H  +    P+P P+    S L+   P  PS
Sbjct: 527 PASLTTPPLENLPSLAPPPLQTASAPLTTPH-LETPPCPAPCPLQAPPSPLTTPPPETPS 585

Query: 140 LLLERPSPKPPAL 152
            +   P   PPAL
Sbjct: 586 SIATPPPQAPPAL 598



 Score = 27.3 bits (59), Expect = 7.4
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 2/51 (3%)

Query: 101 LASPDPRIKHPQDLASTPSPGPMTTSVSSLSASQPPEPSLLLERPSPKPPA 151
           +A+P P+   P  LAS P  G  +  +S L+   P  P  L   P   PP+
Sbjct: 587 IATPPPQA--PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635



 Score = 27.3 bits (59), Expect = 7.4
 Identities = 30/89 (33%), Positives = 37/89 (41%), Gaps = 12/89 (13%)

Query: 71  PPGEVGKRAPDGASRSSL-EPMEDAAPIIYLLASPDPRIKHPQDLASTPSPGPMTTSVS- 128
           PP +V    P     S L +P   A P    LA+P P    P   AS P   P + S S 
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPA---LATP-PLQALPSPPASFPGQAPFSPSASL 819

Query: 129 --SLSASQPPEPSLLLERP----SPKPPA 151
             S  A+ PP+   +L  P     P PPA
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPA 848


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,099,563
Number of Sequences: 37866
Number of extensions: 616503
Number of successful extensions: 5996
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 371
Number of HSP's that attempted gapping in prelim test: 4424
Number of HSP's gapped (non-prelim): 1843
length of query: 182
length of database: 18,247,518
effective HSP length: 96
effective length of query: 86
effective length of database: 14,612,382
effective search space: 1256664852
effective search space used: 1256664852
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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