Guide to the Human Genome
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Search of human proteins with 149158696

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|149158696 HLA-B associated transcript-3 isoform b [Homo
sapiens]
         (1126 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]  2271   0.0  
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]   2271   0.0  
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]   2271   0.0  
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]  2265   0.0  
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     86   2e-16
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    84   6e-16
gi|163965366 nascent polypeptide-associated complex alpha subuni...    84   6e-16
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    82   3e-15
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         81   6e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    80   1e-14
gi|47132519 Ras association and pleckstrin homology domains 1 is...    79   2e-14
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    79   2e-14
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 79   2e-14
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 79   2e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    79   3e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    79   3e-14
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    76   2e-13
gi|160707881 formin 2 [Homo sapiens]                                   75   3e-13
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         75   5e-13
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 73   1e-12
gi|153792074 proline rich 12 [Homo sapiens]                            73   1e-12
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    71   5e-12
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    70   9e-12
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     70   1e-11
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...    69   3e-11
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...    69   3e-11
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...    69   3e-11
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...    69   3e-11
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...    69   3e-11
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...    69   3e-11

>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 2271 bits (5886), Expect = 0.0
 Identities = 1126/1126 (100%), Positives = 1126/1126 (100%)

Query: 1    MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI 60
            MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
Sbjct: 1    MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI 60

Query: 61   YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP 120
            YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
Sbjct: 61   YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP 120

Query: 121  GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL 180
            GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
Sbjct: 121  GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL 180

Query: 181  SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ 240
            SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
Sbjct: 181  SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ 240

Query: 241  NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT 300
            NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
Sbjct: 241  NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT 300

Query: 301  TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT 360
            TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
Sbjct: 301  TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT 360

Query: 361  PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG 420
            PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
Sbjct: 361  PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG 420

Query: 421  APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ 480
            APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
Sbjct: 421  APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ 480

Query: 481  TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG 540
            TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
Sbjct: 481  TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG 540

Query: 541  QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ 600
            QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
Sbjct: 541  QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ 600

Query: 601  FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP 660
            FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
Sbjct: 601  FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP 660

Query: 661  PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI 720
            PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
Sbjct: 661  PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI 720

Query: 721  AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR 780
            AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
Sbjct: 721  AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR 780

Query: 781  SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF 840
            SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
Sbjct: 781  SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF 840

Query: 841  NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV 900
            NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
Sbjct: 841  NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV 900

Query: 901  NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE 960
            NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
Sbjct: 901  NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE 960

Query: 961  PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI 1020
            PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
Sbjct: 961  PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI 1020

Query: 1021 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS 1080
            QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
Sbjct: 1021 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS 1080

Query: 1081 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP 1126
            RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
Sbjct: 1081 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP 1126


>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 2271 bits (5886), Expect = 0.0
 Identities = 1126/1126 (100%), Positives = 1126/1126 (100%)

Query: 1    MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI 60
            MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
Sbjct: 1    MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI 60

Query: 61   YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP 120
            YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
Sbjct: 61   YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP 120

Query: 121  GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL 180
            GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
Sbjct: 121  GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL 180

Query: 181  SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ 240
            SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
Sbjct: 181  SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ 240

Query: 241  NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT 300
            NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
Sbjct: 241  NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT 300

Query: 301  TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT 360
            TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
Sbjct: 301  TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT 360

Query: 361  PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG 420
            PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
Sbjct: 361  PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG 420

Query: 421  APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ 480
            APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
Sbjct: 421  APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ 480

Query: 481  TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG 540
            TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
Sbjct: 481  TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG 540

Query: 541  QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ 600
            QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
Sbjct: 541  QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ 600

Query: 601  FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP 660
            FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
Sbjct: 601  FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP 660

Query: 661  PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI 720
            PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
Sbjct: 661  PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI 720

Query: 721  AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR 780
            AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
Sbjct: 721  AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR 780

Query: 781  SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF 840
            SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
Sbjct: 781  SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF 840

Query: 841  NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV 900
            NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
Sbjct: 841  NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV 900

Query: 901  NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE 960
            NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
Sbjct: 901  NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE 960

Query: 961  PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI 1020
            PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
Sbjct: 961  PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI 1020

Query: 1021 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS 1080
            QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
Sbjct: 1021 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS 1080

Query: 1081 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP 1126
            RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
Sbjct: 1081 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP 1126


>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 2271 bits (5886), Expect = 0.0
 Identities = 1126/1126 (100%), Positives = 1126/1126 (100%)

Query: 1    MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI 60
            MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
Sbjct: 1    MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI 60

Query: 61   YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP 120
            YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
Sbjct: 61   YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP 120

Query: 121  GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL 180
            GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
Sbjct: 121  GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL 180

Query: 181  SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ 240
            SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
Sbjct: 181  SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ 240

Query: 241  NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT 300
            NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
Sbjct: 241  NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT 300

Query: 301  TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT 360
            TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
Sbjct: 301  TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT 360

Query: 361  PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG 420
            PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
Sbjct: 361  PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG 420

Query: 421  APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ 480
            APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
Sbjct: 421  APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ 480

Query: 481  TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG 540
            TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
Sbjct: 481  TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG 540

Query: 541  QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ 600
            QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
Sbjct: 541  QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ 600

Query: 601  FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP 660
            FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
Sbjct: 601  FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP 660

Query: 661  PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI 720
            PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
Sbjct: 661  PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI 720

Query: 721  AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR 780
            AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
Sbjct: 721  AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR 780

Query: 781  SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF 840
            SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
Sbjct: 781  SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF 840

Query: 841  NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV 900
            NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
Sbjct: 841  NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV 900

Query: 901  NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE 960
            NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
Sbjct: 901  NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE 960

Query: 961  PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI 1020
            PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
Sbjct: 961  PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI 1020

Query: 1021 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS 1080
            QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
Sbjct: 1021 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS 1080

Query: 1081 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP 1126
            RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
Sbjct: 1081 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP 1126


>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
          Length = 1132

 Score = 2265 bits (5869), Expect = 0.0
 Identities = 1126/1132 (99%), Positives = 1126/1132 (99%), Gaps = 6/1132 (0%)

Query: 1    MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI 60
            MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
Sbjct: 1    MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI 60

Query: 61   YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP 120
            YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
Sbjct: 61   YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP 120

Query: 121  GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL 180
            GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
Sbjct: 121  GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL 180

Query: 181  SRME------CRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVE 234
            SRME      CRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVE
Sbjct: 181  SRMETLPYLQCRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVE 240

Query: 235  ERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV 294
            ERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV
Sbjct: 241  ERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV 300

Query: 295  LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRP 354
            LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRP
Sbjct: 301  LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRP 360

Query: 355  MSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNV 414
            MSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNV
Sbjct: 361  MSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNV 420

Query: 415  ESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLG 474
            ESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLG
Sbjct: 421  ESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLG 480

Query: 475  PPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQM 534
            PPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQM
Sbjct: 481  PPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQM 540

Query: 535  VSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQP 594
            VSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQP
Sbjct: 541  VSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQP 600

Query: 595  SMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPP 654
            SMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPP
Sbjct: 601  SMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPP 660

Query: 655  PPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARA 714
            PPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARA
Sbjct: 661  PPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARA 720

Query: 715  GSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQR 774
            GSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQR
Sbjct: 721  GSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQR 780

Query: 775  LQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLE 834
            LQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLE
Sbjct: 781  LQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLE 840

Query: 835  FLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIR 894
            FLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIR
Sbjct: 841  FLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIR 900

Query: 895  RMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGA 954
            RMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGA
Sbjct: 901  RMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGA 960

Query: 955  ERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVP 1014
            ERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVP
Sbjct: 961  ERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVP 1020

Query: 1015 IIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLT 1074
            IIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLT
Sbjct: 1021 IIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLT 1080

Query: 1075 SPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP 1126
            SPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
Sbjct: 1081 SPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP 1132


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 97/326 (29%), Positives = 107/326 (32%), Gaps = 34/326 (10%)

Query: 383 GNGTRPPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGP--APPPATSHPRVI 438
           G    PPP      + PPP PG+     P   N     +G PPPG    PPP     R  
Sbjct: 55  GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN---KPQGPPPPGKPQGPPPQGDKSRSP 111

Query: 439 RISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG--QTLGQQVPGFPTAPTRV 496
           R       P           G QP G P  P  P GPP  G  +  G   PG P  P   
Sbjct: 112 R------SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 165

Query: 497 VIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGM 556
              +    ++ P  P GPP  G  Q  G        Q      G     P     G P  
Sbjct: 166 GDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP--PPGKP-Q 222

Query: 557 APPPAPATASASAGTTNTATTAGPAPGGPAQPP-PTPQPSMADLQFSQLLGNLLGPAGPG 615
            PPP     S SA +       GP P G  QP  P P P        Q      GP  PG
Sbjct: 223 GPPPQGDNKSQSARSP-PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281

Query: 616 A-------GGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPP--APEQ 666
                   GGS   S       P  P    G        Q  PPPP  P  PPP    + 
Sbjct: 282 KPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG-----NQPQGPPPPPGKPQGPPPQGGNKP 336

Query: 667 QTMPPPGSPSGGAGSPGGLGLESLSP 692
           Q  PPPG P G     G     + SP
Sbjct: 337 QGPPPPGKPQGPPPQGGSKSRSARSP 362



 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 95/324 (29%), Positives = 109/324 (33%), Gaps = 36/324 (11%)

Query: 383 GNGTRPPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPG-PAPPPATSHPRVIR 439
           G    PPP      + PPP PG+     P   N     +G PPPG P  PP    P+   
Sbjct: 116 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN---KPQGPPPPGKPQGPP----PQGDN 168

Query: 440 ISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG--QTLGQQVPGFPTAPTRVV 497
            S  S  P           G QP G P  P  P GPP  G  +  G   PG P  P    
Sbjct: 169 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557
             +    ++ P  P GPP  G  Q  G        Q      G     P     G P   
Sbjct: 229 DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP--PPGKP-QG 285

Query: 558 PPPAPATASASAGTTNTATTAGPAPGGPAQPP-PTPQPSMADLQFSQLLGNLLGPAGPGA 616
           PPP   + S S+ +       GP P G  QP  P P P        Q      GP  PG 
Sbjct: 286 PPPQGGSKSRSSRSP-PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 344

Query: 617 -------GGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTM 669
                  GGS   S       P  P   +G             P  PPPP    P+Q   
Sbjct: 345 PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNN-----------PQGPPPPAGGNPQQPQA 393

Query: 670 PPPGSPSGGAGSPGGLGLESLSPE 693
           PP G P G    P G G  S  P+
Sbjct: 394 PPAGQPQGPPRPPQG-GRPSRPPQ 416



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 5/85 (5%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           +GG QPQ   PPP  P   P       Q   P      P    + +    R+P   P+  
Sbjct: 124 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183

Query: 246 P---GPAPAGPTPAPETNAPNHPSP 267
           P   G  P GP P P    P  P P
Sbjct: 184 PPQGGNQPQGPPPPP--GKPQGPPP 206



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 5/85 (5%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           +GG QPQ   PPP  P   P       Q   P      P    + +    R+P   P+  
Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245

Query: 246 P---GPAPAGPTPAPETNAPNHPSP 267
           P   G  P GP P P    P  P P
Sbjct: 246 PPQGGNQPQGPPPPP--GKPQGPPP 268



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 26/85 (30%), Positives = 31/85 (36%), Gaps = 5/85 (5%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           +GG QPQ   PPP  P   P       Q   P      P     ++    R+P   P+  
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307

Query: 246 P---GPAPAGPTPAPETNAPNHPSP 267
           P   G  P GP P P    P  P P
Sbjct: 308 PPQGGNQPQGPPPPP--GKPQGPPP 330



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 7/85 (8%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           +GG +PQ   PP +P    P+     S  S P + + PP +       + + P   P   
Sbjct: 84  QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN----QPQGPPPPPGKP 139

Query: 246 PGPAPAG---PTPAPETNAPNHPSP 267
            GP P G   P   P    P  P P
Sbjct: 140 QGPPPQGGNKPQGPPPPGKPQGPPP 164



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 41/150 (27%), Positives = 56/150 (37%), Gaps = 25/150 (16%)

Query: 938  GDPPQP-LPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDG 996
            G PP P  P+ P    G +   P P  +   P P   ++   SR PP  P+G     Q G
Sbjct: 255  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG--PPPQGG 312

Query: 997  ASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLL 1056
               +  P     PP   P   Q    Q   KPQ P       G P       QG  PQ  
Sbjct: 313  NQPQGPP-----PPPGKP---QGPPPQGGNKPQGPPP----PGKP-------QGPPPQ-- 351

Query: 1057 LSEAVSRAAKAAGARPLTSPESLSRDLEAP 1086
               + SR+A++   +P   P+    + + P
Sbjct: 352  -GGSKSRSARSPPGKPQGPPQQEGNNPQGP 380



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 8/86 (9%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALS-SQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           +GG +PQ   PP +P    P+  + S S  S P + + PP +       + + P   P  
Sbjct: 269 QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN----QPQGPPPPPGK 324

Query: 245 TPGPAPAG---PTPAPETNAPNHPSP 267
             GP P G   P   P    P  P P
Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPP 350



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 26/105 (24%), Positives = 34/105 (32%), Gaps = 25/105 (23%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPV---------------ESEAPPREPMEA 230
           +GG QPQ   PPP  P   P       Q   P                 + +PP +P   
Sbjct: 310 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369

Query: 231 EEVEERAP----------AQNPELTPGPAPAGPTPAPETNAPNHP 265
            + E   P           Q P+  P   P GP   P+   P+ P
Sbjct: 370 PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 26/95 (27%), Positives = 40/95 (42%), Gaps = 6/95 (6%)

Query: 938  GDPPQP-LPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDG 996
            G PP P  P+ P    G +   P P  +   P P   ++   +R PP  P+G    +Q+G
Sbjct: 317  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQG--PPQQEG 374

Query: 997  ASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPP 1031
             + +  P  A   P+     Q     Q +  P+PP
Sbjct: 375  NNPQGPPPPAGGNPQQP---QAPPAGQPQGPPRPP 406



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 8/86 (9%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALS-SQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           +GG +PQ   PP +P    P+    S S  S P + + PP +       + + P   P  
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN----QPQGPPPPPGK 200

Query: 245 TPGPAPAG---PTPAPETNAPNHPSP 267
             GP P G   P   P    P  P P
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPP 226



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 8/86 (9%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALS-SQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           +GG +PQ   PP +P    P+    S S  S P + + PP +       + + P   P  
Sbjct: 207 QGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN----QPQGPPPPPGK 262

Query: 245 TPGPAPAG---PTPAPETNAPNHPSP 267
             GP P G   P   P    P  P P
Sbjct: 263 PQGPPPQGGNKPQGPPPPGKPQGPPP 288



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 3/80 (3%)

Query: 188 GPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPG 247
           GP PQ    P  PP    +P     Q     +   PP +P +    +  + +++    PG
Sbjct: 306 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGPPPQGGSKSRSARSPPG 364

Query: 248 PAPAGPTPAPETNAPNHPSP 267
             P GP P  E N P  P P
Sbjct: 365 -KPQGP-PQQEGNNPQGPPP 382



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 19/62 (30%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 938 GDPPQP-LPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPP-----PAPEGGSR 991
           G PP P  P+ P    G +   P P  +   P P    +   SR PP     P P+GG++
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQ 190

Query: 992 DE 993
            +
Sbjct: 191 PQ 192



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 28/106 (26%), Positives = 37/106 (34%), Gaps = 11/106 (10%)

Query: 166 LVMAQHMIRDIQTLLSRMECRGGPQ---PQHSQPPPQPPAVTPEPVALSSQ-TSEPVESE 221
           L  AQ++  D+    S     G PQ   PQ    P  PP+   +P     Q  ++P    
Sbjct: 13  LSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPP 72

Query: 222 APPREPMEAEEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSP 267
            PP +P       +  P Q      GP P G    P        SP
Sbjct: 73  PPPGKP-------QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 111



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 27/103 (26%), Positives = 35/103 (33%), Gaps = 21/103 (20%)

Query: 186 RGGPQPQH--------SQPPPQ-------PPAVTPEPVALSSQTSEPVESEAPPREPM-- 228
           +GG +PQ           PPPQ       PP    +P     Q     +   PP +P   
Sbjct: 42  QGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 101

Query: 229 EAEEVEERAPAQNPELTPGPAPAGPT----PAPETNAPNHPSP 267
             +  + R+P   P    GP P G      P P    P  P P
Sbjct: 102 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 144



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 18/62 (29%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 938 GDPPQP-LPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPP-----PAPEGGSR 991
           G PP P  P+ P    G +   P P  +   P P    +   +R PP     P P+GG++
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252

Query: 992 DE 993
            +
Sbjct: 253 PQ 254


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 91/328 (27%), Positives = 109/328 (33%), Gaps = 43/328 (13%)

Query: 381 MTGNGTRPPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGP--APPPATSHPR 436
           + GN   P P      + PPP PG+     P   N     +G PPPG    PPP     R
Sbjct: 32  IAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGN---KPQGPPPPGKPQGPPPQGDKSR 88

Query: 437 VIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG--QTLGQQVPGFPTAPT 494
             R       P           G QP G P  P  P GPP  G  +  G   PG P  P 
Sbjct: 89  SPR------SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPP 142

Query: 495 RVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP 554
                +   P++ P  P GPP  G  Q  G        Q      G+    P       P
Sbjct: 143 PQG-DKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP-----PP 196

Query: 555 GMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGP 614
           G    P P    + +  +      GP P G  QP   P P           G   GP  P
Sbjct: 197 GKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPP----------GKPQGP--P 244

Query: 615 GAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPP---------PPPPPPPAPE 665
             GG+    P       G PA     +   ++    P  PP         PPPP    P+
Sbjct: 245 PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 304

Query: 666 QQTMPPPGSPSGGAGSPGGLGLESLSPE 693
           Q   PP G P G    P G G  S  P+
Sbjct: 305 QPQAPPAGQPQGPPRPPQG-GRPSRPPQ 331



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 24/86 (27%), Positives = 30/86 (34%), Gaps = 6/86 (6%)

Query: 188 GPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPM--EAEEVEERAPAQNPELT 245
           GP PQ    P  PP    +P     Q     +   PP +P     +  + R+P   P   
Sbjct: 38  GPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 97

Query: 246 PGPAPAGPT----PAPETNAPNHPSP 267
            GP P G      P P    P  P P
Sbjct: 98  QGPPPQGGNQPQGPPPPPGKPQGPPP 123



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 7/85 (8%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           +GG +PQ   PP +P    P+     S  S P + + PP +       + + P   P   
Sbjct: 63  QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN----QPQGPPPPPGKP 118

Query: 246 PGPAPAG---PTPAPETNAPNHPSP 267
            GP P G   P   P    P  P P
Sbjct: 119 QGPPPQGGNRPQGPPPPGKPQGPPP 143



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 24/85 (28%), Positives = 33/85 (38%), Gaps = 7/85 (8%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           +GG +PQ   PP +P    P+     S  S P + + PP +       + + P   P   
Sbjct: 124 QGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN----QPQGPPPPPGKP 179

Query: 246 PGPAPAG---PTPAPETNAPNHPSP 267
            GP P G   P   P    P  P P
Sbjct: 180 QGPPPQGGKKPQGPPPPGKPQGPPP 204



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 27/86 (31%), Positives = 34/86 (39%), Gaps = 8/86 (9%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQ-TSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           +GG QPQ   PPP  P   P       Q    P + + PP  P   +    ++P   P+ 
Sbjct: 164 QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP--PQGDKSRSSQSPPGKPQG 221

Query: 245 TP---GPAPAGPTPAPETNAPNHPSP 267
            P   G  P GP P P    P  P P
Sbjct: 222 PPPQGGNQPQGPPPPP--GKPQGPPP 245



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 3/80 (3%)

Query: 188 GPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPG 247
           GP PQ    P  PP    +P     Q     +   PP +P +    +  + +Q+    PG
Sbjct: 221 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QGPPAQGGSKSQSARSPPG 279

Query: 248 PAPAGPTPAPETNAPNHPSP 267
             P GP P  E N P  P P
Sbjct: 280 -KPQGP-PQQEGNNPQGPPP 297



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 28/107 (26%), Positives = 35/107 (32%), Gaps = 29/107 (27%)

Query: 186 RGGPQPQHSQPP-----------------PQPPAVTPEPVALSSQTSEPVESEAPPREPM 228
           +GG QPQ   PP                 P PP     P A     S+   S  PP +P 
Sbjct: 225 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS--PPGKPQ 282

Query: 229 EAEEVEERAP----------AQNPELTPGPAPAGPTPAPETNAPNHP 265
              + E   P           Q P+  P   P GP   P+   P+ P
Sbjct: 283 GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 329



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 8/87 (9%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           +GG +PQ   PP +P    P+     S  S P + + PP +       + + P   P   
Sbjct: 185 QGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGN----QPQGPPPPPGKP 240

Query: 246 PGPAPAG---PTPAPETNAPNHPSPAE 269
            GP P G   P   P    P  P PA+
Sbjct: 241 QGPPPQGGNKPQGPPPPGKPQGP-PAQ 266



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/96 (27%), Positives = 41/96 (42%), Gaps = 8/96 (8%)

Query: 938  GDPPQPLPEEPMEVQGAERAS--PEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQD 995
            G PP P   +    QG  +    P P +    PA G +  ++ +R PP  P+G    +Q+
Sbjct: 232  GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQS-ARSPPGKPQG--PPQQE 288

Query: 996  GASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPP 1031
            G + +  P  A   P+     Q     Q +  P+PP
Sbjct: 289  GNNPQGPPPPAGGNPQQP---QAPPAGQPQGPPRPP 321



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 32/118 (27%), Positives = 40/118 (33%), Gaps = 14/118 (11%)

Query: 938  GDPPQPLPEEPMEVQGAERAS--PEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQD 995
            G PP P   +    QG  R    P P +    P  G  +     R PP  P+G     Q 
Sbjct: 110  GPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSP--RSPPGKPQG--PPPQG 165

Query: 996  GASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGP 1053
            G   +  P     PP   P   Q    Q   KPQ P       G P +  K+   + P
Sbjct: 166  GNQPQGPP-----PPPGKP---QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP 215


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 103/370 (27%), Positives = 130/370 (35%), Gaps = 44/370 (11%)

Query: 342  ACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTR--PPPTPNAEAPPP 399
            A TPP     V P S   +P     AA P      T    T    +  P  TP  +  P 
Sbjct: 1008 APTPP----AVTPPSPKGSP-----AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT 1058

Query: 400  GPGQASSVAPSSTNVESSAEGAP------PPGPAPPPATSHPRVIRISHQSVEPVVMMHM 453
             P  A+  +P       S +GAP      PP P   PAT  P+   +   +  P     +
Sbjct: 1059 TPA-ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117

Query: 454  NI---QDSGTQPGGVPSAPTGPLG--PPGHGQTLGQQVP-----GFPTAPTRVVIARPTP 503
                 + + T P   P +P G L   PP    T     P     G  T P +     PT 
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK---GAPTT 1174

Query: 504  PQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAP- 562
            P A P  P G   + + +GA     A+      GL       P      T   A PP+P 
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA-----TPSPKGAPTTPAATPPSPK 1229

Query: 563  ---ATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGS 619
               AT S     T  A T     GGPA PPP   P+        L G L  P   GA   
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP 1289

Query: 620  GVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPP---GSPS 676
             V +P      P      +G      AT  +P   P  PPP  AP    + PP   G+P+
Sbjct: 1290 AVVTPPSPKGGPATSP-PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348

Query: 677  GGAGSPGGLG 686
              A +P   G
Sbjct: 1349 LPATTPSSKG 1358



 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 155/661 (23%), Positives = 233/661 (35%), Gaps = 99/661 (14%)

Query: 89   PPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFN-LPSDGSAV 147
            P ++  P+G +  T   ++T+   + P   G   +V     N  V  GT   LP   +A 
Sbjct: 649  PLESADPAGVAPTTAKGTSTYTTTASPFLEG---TVSLAPKNHPVKEGTLTTLPLVPTA- 704

Query: 148  DVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTP-- 205
                  E  P+   P       Q+    + TL+   E      P+    P  PPA TP  
Sbjct: 705  -----SENCPVAPSP-------QNTCAPLATLVLAPEI-----PKSVPSPSLPPAGTPPG 747

Query: 206  -EPVALSSQTSEPVESEAPPRE-PMEAEEVEERAPAQNP--ELTPGPAPAGPTPAPETNA 261
             + V   S TS      + P+E P E       A ++     L   P+P G + +P+T  
Sbjct: 748  TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807

Query: 262  PNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQRLINLVG 321
            P  P+          +  L S + P        + A+   + + + +G ++     +   
Sbjct: 808  P--PTKKGSAGPDTPIGNLSSPVSP--------VEASFLPENSLSFQGSKDSPATTHSPT 857

Query: 322  ESLRLLGNTFVALSDLRCNLACTPPRH------LHVVRPMSHYTTPMVLQQAAIPIQINV 375
                    T  A++ L       PP+       +++  P     TP   Q  A+ +  + 
Sbjct: 858  PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSS 917

Query: 376  GTTVTMT--------GNGTRPPPTPNAEAPP--------------PGPGQASSVAPSSTN 413
                  T            +  PTP A  PP              P P  A+  +P    
Sbjct: 918  PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977

Query: 414  VESSAEGAPPPGPAPP------PATSHPRVI----RISHQSVEPVVMMHMNIQDSGTQPG 463
               S +GAP P  A P      PAT  P+       ++  S +         + + T P 
Sbjct: 978  ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037

Query: 464  GVPSAPTG-----PLGPPGHGQTLGQQVP---GFPTAPTRVVIARPTPPQARPSHPGGPP 515
              P +P G     PL P G   T    +P   G P  P+  +   PTPP A P  P G P
Sbjct: 1038 ATPPSPKGSPAATPL-PKGAPTTPAATLPSPKGGPATPS--LKGAPTPPAATPPSPKGGP 1094

Query: 516  VSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP-----GMAPPP---APATASA 567
             + + +GA +   A+      GL              TP     G+A PP   AP T +A
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154

Query: 568  SAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAG-PGAGGSGVASPTI 626
            +  +        P  G P  P  TP      L      G    PA  P +   G+A+P+ 
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214

Query: 627  TVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPE--QQTMPPPGSPSGGAGSPGG 684
              A P  PA          AT +    P  P   PP+P+    T PP G+P+  A +P  
Sbjct: 1215 KGA-PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPS 1273

Query: 685  L 685
            L
Sbjct: 1274 L 1274



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 85/328 (25%), Positives = 118/328 (35%), Gaps = 60/328 (18%)

Query: 383 GNGTRPPPTPNA-EAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHP---RVI 438
           G  T  P  P A E  P  P   ++ AP +T V +       P P+ PPA + P   +V 
Sbjct: 693 GTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVD 752

Query: 439 RISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVI 498
            ISH S          +    + P   P+  +G         TL         +P  V +
Sbjct: 753 GISHTSA---------LAPVASSPKECPTEDSGASATASSKGTLTYLADS--PSPLGVSV 801

Query: 499 ARPT--PPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGT-PG 555
           +  T  PP  + S     P+             +L+  VS +    L +  L  QG+   
Sbjct: 802 SPQTKRPPTKKGSAGPDTPI------------GNLSSPVSPVEASFLPENSLSFQGSKDS 849

Query: 556 MAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPG 615
            A   +P   S     T +A T     G    P  TP PS+ +L F +      GPA P 
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK-----EGPATPA 904

Query: 616 AGGSGVASPT--------ITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPP------ 661
              +   S T         T A  G+PA          + + AP PP   PP P      
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPA--------SPSPKGAPTPPAATPPSPKGGPAT 956

Query: 662 PAPEQQTMPP---PGSPSGGAGSPGGLG 686
           P+P+    PP   P SP GG  +P   G
Sbjct: 957 PSPKWAPTPPAATPPSPKGGPATPSPKG 984



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 80/328 (24%), Positives = 104/328 (31%), Gaps = 59/328 (17%)

Query: 392  PNAEAPPPGPGQ---ASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPV 448
            P A +P   P +   AS+ A S   +   A+   P G +  P T  P   + S     P+
Sbjct: 762  PVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI 821

Query: 449  VMMH---------------MNIQDSGTQPGGVPS-APTGPLGPPGHGQTLGQQVPGFPTA 492
              +                ++ Q S   P    S  P  P G P    T     P  P  
Sbjct: 822  GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP----TPSAVTPLSPKG 877

Query: 493  PTRVVIARPTPPQARPSHPG-GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQ 551
             T      PTP       P  GP      Q   L   +S  +                A+
Sbjct: 878  VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK---------------AR 922

Query: 552  GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGP 611
             TP  AP   PA+ S     T  A T     GGPA P P   P+          G    P
Sbjct: 923  ATP--APKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980

Query: 612  AGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPP-------PAP 664
            +  GA     A+P      P  P+            + AP PP   PP P       P P
Sbjct: 981  SPKGAPTPPAATPPSPKGGPATPS-----------PKGAPTPPAVTPPSPKGSPAATPFP 1029

Query: 665  EQQTMPPPGSPSGGAGSPGGLGLESLSP 692
            +  + PP  +P    GSP    L   +P
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAP 1057



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 82/339 (24%), Positives = 114/339 (33%), Gaps = 36/339 (10%)

Query: 389  PPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPV 448
            P TP A  P P  G A+     +    ++   +P  G A PP    P     +  S +  
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1185

Query: 449  VMMHMNIQDSGTQPGGVPSAPTGPLGPPGH--GQTLGQQVPGFPTA--PTRVVIARPTPP 504
            +    + + + T P   P +P G L  P      T     P  P     T      PT P
Sbjct: 1186 LATP-SPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244

Query: 505  QARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG---QLLMQPVLVA----QGTPGMA 557
             A P  P G P +   +GA     A+   +  GL     +    P +V     +G P  +
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304

Query: 558  PP-----PAPATASASAGTTNTATTAG---------PAPGG-PAQPPPTPQPSMADLQFS 602
            PP     P  AT  +  G+  T    G         P+P G P  P  TP         S
Sbjct: 1305 PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364

Query: 603  QLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPP 662
               G     A P   G    +P      P +P+         +   T+P   P  P   P
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS--------PKGDPTSPAVIPLSPKKAP 1416

Query: 663  APEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQG 701
            A    T     +PS G  +P  +   SL     TS  +G
Sbjct: 1417 A-TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 110/482 (22%), Positives = 146/482 (30%), Gaps = 111/482 (23%)

Query: 342  ACTPPRH---LHVVRPMSHYTTPMVLQQA-----AIPIQINVGTTVTMT------GNGTR 387
            A TPP     L    P    TTP     +     A P      TT   T      G  T 
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP 1258

Query: 388  PP---PTPNAEAPP--------------PGPGQASSVAPSSTNVESSAEGAPPPGPAPPP 430
            PP   PTP A  PP              P P   +  +P      S  +GAP P  A PP
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318

Query: 431  ATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPG-HGQTLGQQVPGF 489
            +            +  P  +   + + + T P   PS+  GP  P    G T     P  
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378

Query: 490  PTAPTRVVIARPTP--------PQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQ 541
               P    +  P+P        P+  P+ P   P+S     A   T    A    G +  
Sbjct: 1379 KGGPA---MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435

Query: 542  LLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATT-----------------------A 578
              + PV + +     AP   PAT S+    T  A T                       A
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495

Query: 579  GPAPGG-----------PAQPPPTPQPSMADLQFSQLLGNLLGPA--GPGAG----GSGV 621
             PAP G           P + P TP      +  +  L +   PA   P          V
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555

Query: 622  ASPTITVAMPG-------------------VPAFLQGMTD----FLQATQTAPPP----- 653
             SP  T A+P                     P+  +G        +    T+P P     
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615

Query: 654  PPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGAR 713
            PP   PP P     T  P G+P+    +P  L     SP   T  +   +      L A+
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675

Query: 714  AG 715
             G
Sbjct: 1676 KG 1677



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 116/539 (21%), Positives = 164/539 (30%), Gaps = 85/539 (15%)

Query: 186  RGGPQPQHSQPPPQPPAVTPEPVALSSQT------------SEPVESEAPPREPMEAEEV 233
            +GGP     +  P PPA TP  +     T            + P     P   P +    
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311

Query: 234  EERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYE 293
               A   +P+ +PG  P    P P    P  P     +          S+  P      E
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP----SSKGGPTTPSSKE 1367

Query: 294  VLGAAATTDYNNNHEG-----REEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRH 348
                 A T    +H+G         +R   +            + LS  +     TP   
Sbjct: 1368 GPTPPAATP---SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA--PATPVTR 1422

Query: 349  LHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVA 408
                 P     TP     A  P+ +      +    G   P TP+++  P  P       
Sbjct: 1423 EGAATPSKGDLTP----PAVTPVSLKKAPATSAPKGG---PATPSSKGDPTLP------- 1468

Query: 409  PSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSA 468
                          PP P  PPA    +V   S     P     M    + T P  +PS+
Sbjct: 1469 -----------AVTPPSPKEPPAPK--QVATSSSPKKAPATPAPMG---APTLPAVIPSS 1512

Query: 469  PTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTN 528
            P      P   +         P APT  ++++ TP    P     PP             
Sbjct: 1513 PKEVPATPSSRRD--------PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564

Query: 529  ASLAQMVSGLVGQLLMQPVLVAQGTPGMAP-------PPAPATASASAGTTNTATTAGPA 581
             +  +  +    +    P  V   T   AP       PPA  + S     T  A T    
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSP 1624

Query: 582  PGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMT 641
              GPA P P   P+   +  S L  +   PA      +     T+  A  G+PA  +G T
Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASV----TCKMGATVPQASKGLPA-KKGPT 1679

Query: 642  DFLQATQTAPPPPPPP---PPPPPAPEQQ----TMPP-PGSPSGGAGSPGGLGLESLSP 692
              L+    AP P   P    P    P+ +    T PP    PS   GS G L   + +P
Sbjct: 1680 -ALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 114/522 (21%), Positives = 158/522 (30%), Gaps = 161/522 (30%)

Query: 186  RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
            +GGP    S+  P  PAVTP                  P+EP   ++V   +  +    T
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPS----------------PKEPPAPKQVATSSSPKKAPAT 1496

Query: 246  PGPAPAGPTPAPETNAPNH--PSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDY 303
            P P  A   PA   ++P     +P+   + +     L S+  P      E L   A T  
Sbjct: 1497 PAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556

Query: 304  NNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMV 363
            +          +       S                  A +PP             TP  
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKE----------------ASSPPA-----------VTPST 1589

Query: 364  LQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPP 423
             + A  P ++ +   VT      +  PTP A  PP      ++ AP  T           
Sbjct: 1590 YKGAPSPKELLIPPAVTSPS--PKEAPTPPAVTPPSPEKGPATPAPKGT----------- 1636

Query: 424  PGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGV-----PSAPTGPLG-PPG 477
              P  PP T                     +++DS T P  V      + P    G P  
Sbjct: 1637 --PTSPPVTP-------------------SSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675

Query: 478  HGQTLGQQVPGFPTAPTRVVIARPT--PPQARPSHPGGPPVSGTLQGAGLGTNASLAQMV 535
             G T  ++V   P   +  +I  PT   PQ + S    PP+                   
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI------------------- 1716

Query: 536  SGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPS 595
                                  P P     SA  G+    +T  PAP  P Q   +    
Sbjct: 1717 ---------------------CPDP-----SAKNGSKGPLSTVAPAPLLPVQKDSSKTAK 1750

Query: 596  MADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPP 655
              D   S        P GP A     AS  +T A     AF + +     A+ +A P PP
Sbjct: 1751 GKDASHS--------PKGPLAPPESKASTPLTAA-----AFEKVLPKPESASVSAAPSPP 1797

Query: 656  ------PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLS 691
                  P P P   P+QQ +P          S  GL LES S
Sbjct: 1798 VSLPLAPSPVPTLPPKQQFLP----------SSPGLVLESPS 1829



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 86/396 (21%), Positives = 141/396 (35%), Gaps = 66/396 (16%)

Query: 340 NLACTPPRHLHVVRPMS-HYTTPMVLQQ-----------AAIPIQINVGTTVTMTGNGTR 387
           ++ C+P   L+V    S   TT ++L+            A +P+  +VGTT  +  N   
Sbjct: 390 SITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVS-SVGTTPLVVTNPCT 448

Query: 388 PPPTPNAE-------APPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRI 440
               P          +PP   G  S++ P+S      A  AP       P+T     +RI
Sbjct: 449 IAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKE-----PSTQVATTLRI 503

Query: 441 SHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIAR 500
               V P +    ++++       +PS+           QT+   + G P +P +  +  
Sbjct: 504 P---VSPPLPDPEDLKN-------LPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTT 553

Query: 501 PTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPP 560
              P   P     P  S + Q         L+   + L  + L +P+ + +    M    
Sbjct: 554 KKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEAT-LAKKSLGEPLPIGKPASSMT--- 609

Query: 561 APATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSG 620
           +P   ++SA    T + AGP   GP        P++A   F     +  G A   A G+ 
Sbjct: 610 SPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVA--AFPLESADPAGVAPTTAKGTS 667

Query: 621 ----VASP----TITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP------------ 660
                ASP    T+++A    P   +G    L    TA    P  P P            
Sbjct: 668 TYTTTASPFLEGTVSLAPKNHPV-KEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVL 726

Query: 661 ----PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSP 692
               P +    ++PP G+P G     G     +L+P
Sbjct: 727 APEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 41/174 (23%), Positives = 63/174 (36%), Gaps = 9/174 (5%)

Query: 97   GASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQA 156
            G ++ +   + T    +PP  +G  A+   + A +     T   P  G A          
Sbjct: 1208 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT-TPAATPPSPKGGPATPPPKGAPTP 1266

Query: 157  PIQSEPRVR--LVMAQHMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQT 214
            P  + P ++  L    H       +++    +GGP     +  P PPA TP     S  T
Sbjct: 1267 PAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGT 1326

Query: 215  SEPVESEAPPREPMEAEEVEERAPAQNPELTPGP----APAGPTPAPETNAPNH 264
              P  +  PP     + +     PA  P    GP    +  GPTP   T  P+H
Sbjct: 1327 PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT--PSH 1378



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 52/216 (24%), Positives = 75/216 (34%), Gaps = 17/216 (7%)

Query: 381 MTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRI 440
           M G  T   P    E P P    A  V P S+ +  +A    P    PPP +  P+   +
Sbjct: 1   MPGEATETVPATEQELPQPQAETA--VLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58

Query: 441 SHQSVEPVVMMHMNIQDSGTQPGGVPSAPTG---PLGPPGHGQTLGQQVPGFPTAPTRVV 497
           S  +          I  +  +    P + +G   PLG      T    + G P +P  + 
Sbjct: 59  SAANQASPFPSPSTIASTPLEV-PFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALA 117

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPG-- 555
           +A    P   P+  G P  S  L    L  ++   Q  S     LL  P  VA    G  
Sbjct: 118 LA---SPMIAPTLKGTPSSSAPLALVALAPHS--VQKSSAFPPNLLTSPPSVAVAESGSV 172

Query: 556 --MAPPPAPATASASAGTTNTATTAGPAPGGPAQPP 589
             ++ P AP+    +     +     P P G   PP
Sbjct: 173 ITLSAPIAPSEPKTNLNKVPSEVV--PNPKGTPSPP 206



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 45/195 (23%), Positives = 71/195 (36%), Gaps = 23/195 (11%)

Query: 922  HMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRG 981
            H P GP A          PP+     P+     E+  P+P+  + S AP       ++  
Sbjct: 1756 HSPKGPLA----------PPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS 1805

Query: 982  PPPA--PEGGSRDEQDGASAE--TEPWAAAVPPEWVPIIQQD-------IQSQRKVKPQP 1030
            P P   P+        G   E  ++P A A   E +P+I  +        QS     P P
Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTP 1865

Query: 1031 PLSDAYLSGMPAKR--RKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEV 1088
              +   +    AK+   K  +G G +    E+V    +    +  T    L+   E  E 
Sbjct: 1866 KSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEE 1925

Query: 1089 QESYRQQLRSDIQKR 1103
              S  +Q RS+ + R
Sbjct: 1926 PVSKAKQSRSEKKAR 1940



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 86/381 (22%), Positives = 128/381 (33%), Gaps = 75/381 (19%)

Query: 365 QQAAIPIQINVGTTVTMTGNG-TRPPP-----------TPNAEAPPPGPGQASSVAPSST 412
           + A +P+   +  T  +   G T PPP             N  +P P P   +S      
Sbjct: 22  ETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP 81

Query: 413 NVESSAEGAPPPGPAPPPATSHPRVI--------------------RISHQSVEPVVMM- 451
             +SS+  A P G AP   T  P +I                    + +  S  P+ ++ 
Sbjct: 82  FPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVA 141

Query: 452 ---HMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQV-PGFPTA-----PTRVVI---A 499
              H   + S   P  + S P+  +   G   TL   + P  P       P+ VV     
Sbjct: 142 LAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKG 201

Query: 500 RPTPP---QARPSHPGGPPVSGTLQGAGLG--TNASLAQMVSGLVGQLLMQPVLVAQGTP 554
            P+PP      P H   P  S     A L   T  +   + S  V    +  VL++   P
Sbjct: 202 TPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNP 261

Query: 555 G---MAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTP---QPSMADLQFSQLLG-N 607
           G   +  P +P  A + +  +    T+     GP  PP  P      +A L  S      
Sbjct: 262 GSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQ 321

Query: 608 LLGPAGPGA-------------GGSGVASPTITVAMPGVPAFLQGMTDFLQATQTA-PPP 653
           LLG  GP A               +G + P+    +P +P+      + + AT  A P  
Sbjct: 322 LLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPS----RNEVVPATVAAFPVV 377

Query: 654 PPPPPPPPPAPEQQTMPPPGS 674
            P     P      T  P GS
Sbjct: 378 APSVDKGPSTISSITCSPSGS 398



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 89/434 (20%), Positives = 147/434 (33%), Gaps = 47/434 (10%)

Query: 191  PQHSQPPPQPPAVTPEPVA-LSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL-TPGP 248
            P   +  P  P+   +P+A  ++  S+   +   P+E +    +   +P + P + TP  
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 249  APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHE 308
            APA P+ + E ++P   +P+ Y       + L                 A T        
Sbjct: 1570 APATPS-SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628

Query: 309  GREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAA 368
                 +        +   L ++  + + + C +  T P+    +      T    +  A 
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688

Query: 369  IPIQINVGTTVTMTG------NGTRPPPTPNAEAPPPGPGQASSVAP---------SSTN 413
             P    + T  T  G      + T PP  P+  A     G  S+VAP         SS  
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKT 1748

Query: 414  VESSAEGAPPPGP-APPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGP 472
             +       P GP APP + +   +   + + V P             +   V +AP+ P
Sbjct: 1749 AKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP-----------KPESASVSAAPSPP 1797

Query: 473  LGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLA 532
            +                P AP+ V    P   Q  PS PG    S +   A    +  L 
Sbjct: 1798 V--------------SLPLAPSPVP-TLPPKQQFLPSSPGLVLESPSKPLAPADEDELLP 1842

Query: 533  QM-VSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPT 591
             +    + G +  Q VLV   TP  A  P P  ++    T N   +   +    + P   
Sbjct: 1843 LIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELE 1902

Query: 592  PQPS-MADLQFSQL 604
             Q S  A  Q +QL
Sbjct: 1903 EQDSTQATTQQAQL 1916



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 18/72 (25%), Positives = 26/72 (36%), Gaps = 4/72 (5%)

Query: 943  PLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETE 1002
            P    P +       S  P++  A+PAP         +G P  P       + G +  + 
Sbjct: 900  PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959

Query: 1003 PWA----AAVPP 1010
             WA    AA PP
Sbjct: 960  KWAPTPPAATPP 971



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 49/194 (25%), Positives = 62/194 (31%), Gaps = 24/194 (12%)

Query: 88   APPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAV 147
            +P  T  P GAS        T    +PP  +G  A+             T   P  G A 
Sbjct: 1022 SPAATPFPKGAS--------TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073

Query: 148  DVHINMEQAPIQSEPRVRLVMAQHMIRD--IQTLLSRMECRGG-PQPQHSQPPPQPPAVT 204
                     P  + P  +   A    +   +    +    +GG   P H   P  P A  
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133

Query: 205  PEP---VALSSQTSEPVESEAPPREPME--AEEVEERAPAQNPELTPGPAPAG------P 253
            P P   +A       P    A P  P    A    + AP   P  TP P+P G      P
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT-TPAATP-PSPKGGLATPSP 1191

Query: 254  TPAPETNAPNHPSP 267
              AP T A   PSP
Sbjct: 1192 KGAPTTPAATPPSP 1205



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 38/145 (26%), Positives = 50/145 (34%), Gaps = 27/145 (18%)

Query: 558 PPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAG 617
           P P   TA     +  + T A   PG    PP +P P    L       +    A P   
Sbjct: 17  PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL-------SAANQASPFPS 69

Query: 618 GSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPP---PPPPPPPPAPEQQTMPPP-- 672
            S +AS  + V  P      Q  +       TAP  P   P    PP +P    +  P  
Sbjct: 70  PSTIASTPLEVPFP------QSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMI 123

Query: 673 -----GSPSGGAGSPGGLGLESLSP 692
                G+PS  A     L L +L+P
Sbjct: 124 APTLKGTPSSSA----PLALVALAP 144


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 159/640 (24%), Positives = 219/640 (34%), Gaps = 70/640 (10%)

Query: 87  RAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVH-DRNANSYVMVGTFNLPSDGS 145
           R  P T  P  + S     S T    SP   R P A     R A+  +      L S   
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254

Query: 146 AVDVHINMEQAPIQ-SEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQP--PPQPPA 202
           +        +AP   S+P+ + + A   +R  Q    R +      P  S P   P P  
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQA---LRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311

Query: 203 VTPEPVALSSQTSEPVESEAPPREPMEAE-EVEERAPAQNPELTPGPAPAGPTPA---PE 258
               PV      + P+ +  PP  P+     +   +P+  P L   P+P    P+   P 
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371

Query: 259 TNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAA---ATTDYNNNHEGREEDQR 315
              P   +P   ++ +  +Q   S   P LQ     L  +   ATT       G    Q 
Sbjct: 372 MTTPPMQAPPS-LQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL-----GSPTLQA 425

Query: 316 LINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMV---LQQAAIPIQ 372
             + +  S R    +  + S      A TPP    +  P+S   +P +   L  A  P+ 
Sbjct: 426 THSFLTMSPRQTQASLTSPS----RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLS 481

Query: 373 --INVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPP----PGP 426
             + +     ++   +  P  P +    P     SS+AP S     ++   PP    P  
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL 541

Query: 427 APPPATSHPRVIRISHQSVEPV---VMMHMNIQDSGTQPGGVPS--APTGPLGPPGHGQT 481
           APPP  +    +   H    P      +        T P   PS  A   P  PP     
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASP 601

Query: 482 LGQQVPGFPTAPTRV-------VIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQM 534
             Q +P  P +P           +A P P QA PS P  PP+S     +    NA     
Sbjct: 602 PLQGLPSPPLSPLATPPPQAPPXLALP-PLQAPPSPPASPPLSPLATPSPQAPNA----- 655

Query: 535 VSGLVGQLLMQPVLVAQGTPGMAP--PPA--PATASASAGTTNTATTAGPAPGGPAQPPP 590
              L   LL  P       P  AP  PPA  P + SA+  +    + A P    P  PP 
Sbjct: 656 ---LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 712

Query: 591 TPQPSMADLQFSQLLGNLLGP---AGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT 647
           +P  S +     Q    L  P     P    S   SP+ T   P VP  L      LQ  
Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT-PPPRVPPLLAAPP--LQVP 769

Query: 648 QTAP---PPPPPPPPPPPAPEQQTMPP-PGSPSGGAGSPG 683
            + P   P  P   PPP AP     PP    PS  A  PG
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809



 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 145/573 (25%), Positives = 192/573 (33%), Gaps = 75/573 (13%)

Query: 191  PQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP-- 248
            P  +Q    PP++   P +L++   E + S APP  P++        P       P P  
Sbjct: 511  PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPP--PLQTASAPLTTPHLETPPCPAPCP 568

Query: 249  --APAGP--TPAPETNAPNHPSPAEYVEVLQE--LQRLESR-LQPFLQRYYEVLGAAATT 301
              AP  P  TP PET +     P +    L    LQ L S  L P      +     A  
Sbjct: 569  LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALP 628

Query: 302  DYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTP 361
                          L  L   S +      V L     +   +PP       P S   +P
Sbjct: 629  PLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 362  MVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGA 421
                 +  P  +              PP +P+A  PP  P     +A     V  S   +
Sbjct: 688  SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP---PPLAAPPLQVPPSPPAS 744

Query: 422  PPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSA-PTGPLGP-PGHG 479
            PP  P+  P    P ++      V P     + +      P   P A  T PL   P   
Sbjct: 745  PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804

Query: 480  QTLGQQVPGFPTAPTRVVIARPTPPQARP-------SHPGGPPVSGTLQGAGLGTNASLA 532
             +   Q P  P+A   +      PPQA P         P  PP S TLQ           
Sbjct: 805  ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864

Query: 533  QMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASAS-----AGTTNTATT---------A 578
              VSG        P L     PG  PPP+ + +S       AG +++AT+         +
Sbjct: 865  TSVSG--------PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916

Query: 579  GPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQ 638
            GP  G  A PPP      A+L          GPA P A      +P     +P  PA   
Sbjct: 917  GPEGGAAASPPPD-----AELAACHPAAWSRGPAPPLAFRGAPGAP-----LPWPPATGP 966

Query: 639  GMTDFLQAT-QTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPE---- 693
            G  D L    +T  P    P P    P     P PG+  G A +  G G  S SP+    
Sbjct: 967  GSADGLCTIYETEGPESATPAPGALDPG----PSPGTSGGKAAAGAGAGASSRSPKQARL 1022

Query: 694  -------FFTSVVQGVLSS---LLGSLGARAGS 716
                      SVVQ +LS    L  + GA  GS
Sbjct: 1023 GELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 1055



 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 108/406 (26%), Positives = 145/406 (35%), Gaps = 86/406 (21%)

Query: 346 PRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRP-PPTPNAEAP-----PP 399
           P+ L  +RP            A  P+  +   T + +G   RP PP  NA  P     PP
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP 333

Query: 400 GPGQASSV--APSSTNVESSAEGAP-----PPGPAPPPATSHPRVIRISHQSVEPVVMMH 452
            P  A+ +  AP S +   S +  P     PP  APP  T+ P     S Q++ P+ + H
Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH 393

Query: 453 MNIQDSGTQPGGVPSA-----PTGPLGPPGHGQTLG------QQVPGFPTAPTRVVIARP 501
            ++     Q    P A      T  LG P    T        +Q     T+P+R     P
Sbjct: 394 -SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452

Query: 502 TPP--QARPSHPGGPPVSGTLQGAGLGTNASLA----QMVSGLVGQL-------LMQPVL 548
             P  QA  S P  PP+  +L  A    ++ L     Q +S L           L+ P L
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPL 512

Query: 549 VAQGT---------------------PGMAPPPAPATASASAGTTNTATTAGPAPGGPAQ 587
             Q +                     P +APPP   TASA   T +  T   PAP  P Q
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ-TASAPLTTPHLETPPCPAPC-PLQ 570

Query: 588 PPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT 647
            PP+P               L  P            P    A+   P  LQG+       
Sbjct: 571 APPSP---------------LTTPPPETPSSIATPPPQAPPALASPP--LQGLP------ 607

Query: 648 QTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPE 693
             +PP  P   PPP AP    +PP  +P     SP    L + SP+
Sbjct: 608 --SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 100/446 (22%), Positives = 139/446 (31%), Gaps = 77/446 (17%)

Query: 196  PPPQPPAVTP--EPVALSSQTSEPVESEAPPR---EPMEAEEVEERAPAQNPELTPGPAP 250
            PPP PP   P   P +     S    S+APP     P++       +P  +P  TP P  
Sbjct: 667  PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726

Query: 251  AGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGR 310
              P  AP    P  P PA     +        R+ P L      +  +       +   +
Sbjct: 727  PPPLAAPPLQVPPSP-PAS--PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783

Query: 311  EEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIP 370
               Q    L    L+ L +               PP       P S   +  +   A  P
Sbjct: 784  PPPQAPPALATPPLQALPS---------------PPASFPGQAPFSPSASLPMSPLATPP 828

Query: 371  IQINVGTTVTMTGNGTRPPPTPNAEAP--PPGPGQASSVAPSSTNVESSAEGAPPPGPAP 428
             Q        +      PP +P  +AP  PP PG  +SV  S   +  +    PPP P+ 
Sbjct: 829  PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV--SGPRLTLALAPGPPPPPSR 886

Query: 429  PPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPG 488
             P+++        H S        +   DSG + G   S P              +    
Sbjct: 887  SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD-----------AELAAC 935

Query: 489  FPTAPTRVVIARPTPPQARPSHPGG----PPVSGTLQGAGLGTNASLAQMVSGLVGQLLM 544
             P A +R     P PP A    PG     PP +G     GL T                 
Sbjct: 936  HPAAWSR----GPAPPLAFRGAPGAPLPWPPATGPGSADGLCT----------------- 974

Query: 545  QPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQL 604
              +   +G     P P       S GT+     AG   G  ++ P   Q  + +L    L
Sbjct: 975  --IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP--KQARLGELPLGAL 1030

Query: 605  LGN----------LLGPAGPGAGGSG 620
              +          LL  A   AGGSG
Sbjct: 1031 QASVVQHLLSRTLLLAAAEGAAGGSG 1056



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 80/310 (25%), Positives = 105/310 (33%), Gaps = 42/310 (13%)

Query: 399 PGPGQASSVAPSSTNVESSAEGAPPPGPA--PPPATSHPRVIRIS---HQSVEPVVMMHM 453
           P PG  S      +    +  G P P P+  P P T  PR    S   H + EP      
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226

Query: 454 NIQDSG--TQPGGVP-SAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARP------TPP 504
                G   +P     S+   PL  P      G    G P AP      +P       PP
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARS---GPSARGTPRAPAHPSQPKPKGLQALRPP 283

Query: 505 QARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPP----- 559
           Q  P      P  G L  + L T +      SG   + +  P   A   P   PP     
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSP-----SGTKARPVPPPDNAATPLPATLPPSPPLA 338

Query: 560 -PAPATASASAGTTNTATTAGPAPGGPAQPPP---TP----QPSMADLQFSQLLGNLLGP 611
            P P    + +   +  T   P    P+Q PP   TP     PS+  +   Q+  +L  P
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSP 398

Query: 612 ---AGPGAGGSGVASPTITVAMPGVPA---FLQGMTDFLQATQTAPPPPPPPPPPPPAPE 665
              A P          T ++  P + A   FL       QA+ T+P  P   PP  P P 
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP-PL 457

Query: 666 QQTMPPPGSP 675
           Q  +  P SP
Sbjct: 458 QAPLSLPASP 467



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 75/287 (26%), Positives = 100/287 (34%), Gaps = 28/287 (9%)

Query: 422 PPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVP-SAPTGPLGPPGHGQ 480
           PP  P PPP  + P  +R+   +   V    +  +  G     +P SAP    GP     
Sbjct: 29  PPGSPRPPPPVT-PAALRVLG-AAGAVGRKPLAERAGGIGGATIPESAPRA--GPTRSAG 84

Query: 481 TLGQQVPGFPTAPTRVVIARPTP-----PQARPSHPGGPPVSGTLQGAGLGTNASLAQMV 535
           T  +     P A  R   A P       P + P    G    G L   GL  +A    + 
Sbjct: 85  TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE-ETVA 143

Query: 536 SGLVGQLLMQPVLVAQG-------TPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQP 588
            G   +   +  L A         TPG  P PA A  S +AGT        PAP    + 
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPG-TPSPAMARRSRAAGTE--VGLPRPAPSARPR- 199

Query: 589 PPTPQPSMADLQFSQLLGNLLGPAG---PGAGGSGVASPTITVAMPGVPAFLQGMTDFLQ 645
           PPT  P  +    S+       PA    P AGG      + +++    P  L        
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP--LSSPARSGP 257

Query: 646 ATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSP 692
           + +  P  P  P  P P   Q   PP  +P     +P  LG  S SP
Sbjct: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP-ALGPLSSSP 303



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 46/197 (23%), Positives = 60/197 (30%), Gaps = 28/197 (14%)

Query: 501 PTPPQA-RPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPP 559
           P PP + RP  P  P     L  AG      LA+   G+ G  +          P  AP 
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI----------PESAPR 76

Query: 560 PAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGS 619
             P T SA   + N A+   PA G   + PP    S   +           P   G  G 
Sbjct: 77  AGP-TRSAGTSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134

Query: 620 GVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPP---------------PPPAP 664
            +++           A  +          T+ P P  P P               P PAP
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194

Query: 665 EQQTMPPPGSPSGGAGS 681
             +  PP   P     S
Sbjct: 195 SARPRPPTEGPRKSVSS 211



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 45/197 (22%), Positives = 69/197 (35%), Gaps = 29/197 (14%)

Query: 88  APPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMV------GTFNLP 141
           AP ++ L +GA   T         G  PGT  P  +   R A + V +           P
Sbjct: 150 APKRSALSAGARRDTS--------GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201

Query: 142 SDGSAVDVHINMEQAPIQSEPRVRLVM---------AQHMIRDIQTLLSRMECRGGPQPQ 192
           ++G    V    E +  +  P  R            A   +    T LS    R GP  +
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS-PARSGPSAR 260

Query: 193 HSQPPPQPPAVTPEPVALSS----QTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
            +   P  P+  P+P  L +    Q + P +  AP   P+ +  +   +P+        P
Sbjct: 261 GTPRAPAHPS-QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP 319

Query: 249 APAGPTPAPETNAPNHP 265
                TP P T  P+ P
Sbjct: 320 PDNAATPLPATLPPSPP 336



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 35/146 (23%), Positives = 54/146 (36%), Gaps = 13/146 (8%)

Query: 941  PQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAE 1000
            P  LP  P        A+P P    A P+P           PP  P   +         +
Sbjct: 328  PATLPPSP------PLATPLPL---APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ 378

Query: 1001 TEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEA 1060
              P    +PP  VP     + S     P  PL+ + L    +    T+Q     L +S  
Sbjct: 379  APPSLQTIPPIQVP---HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435

Query: 1061 VSRAAKAAGARPLTSPESLSRDLEAP 1086
             ++A+  + +RP ++P   S  L+AP
Sbjct: 436  QTQASLTSPSRPASTPPD-SPPLQAP 460



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 23/73 (31%), Positives = 30/73 (41%), Gaps = 4/73 (5%)

Query: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVES--EAPPREPMEAEEVEERAPAQNPELTP 246
           P    + PPPQ P V   P+ L    S P     +AP R P    +     P     L P
Sbjct: 820 PMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878

Query: 247 GPAPAGPTPAPET 259
           GP P  P+ +P +
Sbjct: 879 GPPPP-PSRSPSS 890



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 40/145 (27%), Positives = 52/145 (35%), Gaps = 11/145 (7%)

Query: 561 APATASASAGTTNTATTAGPAPGGPAQPPPTPQP-SMADLQFSQLLGNLLGPAGPGAGGS 619
           A A A+A            P P G  +PPP   P ++  L  +  +G    P    AGG 
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGR--KPLAERAGGI 65

Query: 620 GVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSG-- 677
           G A  TI  + P         T    +   A  PP         P + T P P S  G  
Sbjct: 66  GGA--TIPESAPRAGPTRSAGT---SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120

Query: 678 -GAGSPGGLGLESLSPEFFTSVVQG 701
            G   PG LG + L      +V +G
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARG 145



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 31/148 (20%), Positives = 53/148 (35%), Gaps = 11/148 (7%)

Query: 940  PPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASA 999
            P  P   +P  +Q        P R++A+PA G  +   ++    P+P G           
Sbjct: 266  PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA---TPSPSGTKARPVPPPDN 322

Query: 1000 ETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSE 1059
               P  A +PP         + +   + P  P +   L  +P+    T   + P  + + 
Sbjct: 323  AATPLPATLPP------SPPLATPLPLAPPSPSAPPSLQTLPSP-PATPPSQAPPSMTTP 375

Query: 1060 AVSRAAKAAGARPLTSPESL-SRDLEAP 1086
             +          P+  P SL S  L+AP
Sbjct: 376  PMQAPPSLQTIPPIQVPHSLTSPSLQAP 403


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 164/675 (24%), Positives = 228/675 (33%), Gaps = 116/675 (17%)

Query: 87  RAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSA 146
           R PP T L  G  S      +     + P   GPG     R A+         +PS GS+
Sbjct: 150 RVPPTTPLNGGPGSLPPEPPSV--SQAFPTLAGPGGLFPPRLADP--------VPSGGSS 199

Query: 147 VDVHINMEQAPIQSEPRVRLVM----AQHMIRDIQTLLSRMECRGGPQPQHSQPPPQPP- 201
               +    AP  + P    +     + +    +++ L   +    P P  S  PP  P 
Sbjct: 200 SPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPP 259

Query: 202 ------AVTPEPVALSSQ-------TSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
                 A+TP P+  S+         S+P  S A    P+    +      + P   P  
Sbjct: 260 LFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFL 319

Query: 249 APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHE 308
           A +  + A +   P  P P+        LQ    R Q            A +  ++++  
Sbjct: 320 ASSLLSAAAKAQHPPLPPPST-------LQGRRPRAQ------------APSASHSSSLR 360

Query: 309 GREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAA 368
             +   R    V   L   G      S  R       P+   +  P S    P VL    
Sbjct: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRS--RPRAPAPVPQPFSLPEP-SQPILPSVLSLLG 417

Query: 369 IPI---QINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPG 425
           +P      + G+   +  +   PPP   +   PP P     + PS     S +  + P  
Sbjct: 418 LPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHP--IQPSLPGTTSGSLSSVPGA 475

Query: 426 PAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGP------PGHG 479
           PAPP A+  P V         PV+         G   G  P+ P  PL        P   
Sbjct: 476 PAPPAASKAPVV-------PSPVLQS----PSEGLGMGAGPACPLPPLAGGEAFPFPSPE 524

Query: 480 QTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLV 539
           Q L     GFP     ++ A P P        G PP S  L       N SL  +++G  
Sbjct: 525 QGLALSGAGFPG----MLGALPLPLSL-----GQPPPSPLL-------NHSLFGVLTGGG 568

Query: 540 GQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADL 599
           GQ   +P+L   G PG  PP AP       G +    +  P P     PPP+  PS    
Sbjct: 569 GQPPPEPLLPPPGGPG--PPLAPGEPE---GPSLLVASLLPPPPSDLLPPPSAPPSNLLA 623

Query: 600 QFSQLLG-------------NLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQA 646
            F  LL                 GP+G    G G  SP +   +   P  +   +  L A
Sbjct: 624 SFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAA 683

Query: 647 TQTAPPPPPPPP---------PPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTS 697
           T   P   PP P         PP  +    T  P  S  G A S  G   + LSP    S
Sbjct: 684 TLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGAS 743

Query: 698 VVQGVLSSLLGSLGA 712
           ++ G LSSL  S GA
Sbjct: 744 LL-GDLSSLTSSPGA 757



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 137/590 (23%), Positives = 194/590 (32%), Gaps = 138/590 (23%)

Query: 194 SQPPPQPPAVTPE---PVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAP 250
           +Q PP PP  T +   P A +   S         R P     V      + P+      P
Sbjct: 330 AQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRP 389

Query: 251 AGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGR 310
             P P P+  +   PS                  QP L     +LG            G 
Sbjct: 390 RAPAPVPQPFSLPEPS------------------QPILPSVLSLLGLPT--------PGP 423

Query: 311 EEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIP 370
                  NL+G    L     ++        + +PP+  H ++P    TT   L  +++P
Sbjct: 424 SHSDGSFNLLGSDAHLPPPPTLS--------SGSPPQPRHPIQPSLPGTTSGSL--SSVP 473

Query: 371 IQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVA---PSSTNVESSAEGAPPPGPA 427
                G       +     P+P  ++P  G G  +  A   P     E+    +P  G A
Sbjct: 474 -----GAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLA 528

Query: 428 ------PPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPP--GHG 479
                 P    + P  + +      P+    +N    G   GG    P  PL PP  G G
Sbjct: 529 LSGAGFPGMLGALPLPLSLGQPPPSPL----LNHSLFGVLTGGGGQPPPEPLLPPPGGPG 584

Query: 480 QTLGQQVPGFPTAPTRVVIA-RPTPPQARPSHPGGP---------------PVSGTLQGA 523
             L    PG P  P+ +V +  P PP      P  P               P +G  +G+
Sbjct: 585 PPL---APGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGS 641

Query: 524 GLGTNASLAQMVSGL--VGQLLMQPV-----LVA-------------QGTPGM-----AP 558
             G      +  SGL  +  LL  P+     L+A              GTP       AP
Sbjct: 642 AEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP 701

Query: 559 PPAPATASASAGTTNT-ATTAGPAPGGPAQPPPTPQPSMADLQFSQL---------LGNL 608
            P P T+S +  TT+  A++ G AP    +PP    P +       L         L +L
Sbjct: 702 QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSL 761

Query: 609 LGPAGPGAGG--------SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPP--- 657
           L P GP   G         G A P ++ A   +   LQ +    +  +    PP  P   
Sbjct: 762 LQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASA 821

Query: 658 --PPPPPAPEQQTMPPPGSP------------SGGAGSPGGLGLESLSPE 693
             P P   P     PP GSP            SG  G  GG GL  ++ E
Sbjct: 822 LEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGE 871



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 97/381 (25%), Positives = 121/381 (31%), Gaps = 71/381 (18%)

Query: 383 GNGTRPPPTP------NAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPR 436
           GN   P P P      NA +   G    SS+ PS         G+PP   A     S P 
Sbjct: 207 GNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDL-------GSPPAPHASSSPPSDPP 259

Query: 437 VIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGP--------LGPPGHGQTLGQQVPG 488
           +   S     P +    N+      PG     P           LGP G   T+  + PG
Sbjct: 260 LFHCSDALTPPPLPPSNNLP---AHPGPASQPPVSSATMHLPLVLGPLGGAPTV--EGPG 314

Query: 489 FPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVL 548
            P      +++      A+  HP  PP S TLQG      A  A   S L          
Sbjct: 315 APPFLASSLLS----AAAKAQHPPLPPPS-TLQGRRPRAQAPSASHSSSL---------- 359

Query: 549 VAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNL 608
                P    P  P T           T   P    P  P P PQP         +L ++
Sbjct: 360 ----RPSQRRPRRPPTVFRLLEGRGPQT---PRRSRPRAPAPVPQPFSLPEPSQPILPSV 412

Query: 609 LGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQT 668
           L   G              +  PG P+   G  + L +    PPPP      PP P    
Sbjct: 413 LSLLG--------------LPTPG-PSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPI 457

Query: 669 MPP-PGSPSGGAGS-PGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQR 726
            P  PG+ SG   S PG     + S      V   VL S    LG  AG     A  +  
Sbjct: 458 QPSLPGTTSGSLSSVPGAPAPPAASKA--PVVPSPVLQSPSEGLGMGAGP----ACPLPP 511

Query: 727 LSGSSNIFEPGADGALGFFGA 747
           L+G      P  +  L   GA
Sbjct: 512 LAGGEAFPFPSPEQGLALSGA 532



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 62/245 (25%), Positives = 79/245 (32%), Gaps = 71/245 (28%)

Query: 481 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG 540
           T     PG   +P       P PP ARP  P   P +  L G                 G
Sbjct: 120 TCSHSSPGEGASPQMFHTVSPGPPSARP--PCRVPPTTPLNGG---------------PG 162

Query: 541 QLLMQPVLVAQGTPGMAPP----------PAPATASASAGTTNTATTAGPAPGGPAQPPP 590
            L  +P  V+Q  P +A P          P P+  S+S           PA      PPP
Sbjct: 163 SLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPA------PPP 216

Query: 591 TPQPSM--------ADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTD 642
            P  S+        A L+ S +  +L  P  P A  S  + P +                
Sbjct: 217 PPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL---------------- 260

Query: 643 FLQATQTAPPPPPPPPPPPPAPEQQTMPPPGS----------PSGGAGSPGGLGLESLSP 692
           F  +    PPP PP    P  P   + PP  S          P GGA +  G G    +P
Sbjct: 261 FHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPG----AP 316

Query: 693 EFFTS 697
            F  S
Sbjct: 317 PFLAS 321



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 69/267 (25%), Positives = 86/267 (32%), Gaps = 41/267 (15%)

Query: 416 SSAEGAPPP-----GPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPT 470
           S  EGA P       P PP A    RV         P   ++        +P  V  A  
Sbjct: 125 SPGEGASPQMFHTVSPGPPSARPPCRV--------PPTTPLNGGPGSLPPEPPSVSQAFP 176

Query: 471 GPLGPPG-HGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNA 529
              GP G     L   VP   ++  R +     P  A P     PP + +L        A
Sbjct: 177 TLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPP-----PPPAISLNAPSYNWGA 231

Query: 530 SLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPP 589
           +L    S LV   L  P      +   + PP    + A        +   PA  GPA  P
Sbjct: 232 ALR---SSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQP 288

Query: 590 PTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQT 649
           P    +M        L  +LGP G             TV  PG P FL   +  L A   
Sbjct: 289 PVSSATMH-------LPLVLGPLGGAP----------TVEGPGAPPFL--ASSLLSAAAK 329

Query: 650 APPPPPPPPPPPPAPEQQTMPPPGSPS 676
           A  PP PPP        +   P  S S
Sbjct: 330 AQHPPLPPPSTLQGRRPRAQAPSASHS 356



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 22/68 (32%), Positives = 26/68 (38%), Gaps = 3/68 (4%)

Query: 191 PQHSQPPPQPPAVTPEPVALSSQTSEPVESEA---PPREPMEAEEVEERAPAQNPELTPG 247
           P    PPP   A +P    L S    P + EA   PP  P  A E E   P  +    P 
Sbjct: 779 PGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838

Query: 248 PAPAGPTP 255
            +P  P P
Sbjct: 839 GSPDPPVP 846


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 171/694 (24%), Positives = 238/694 (34%), Gaps = 122/694 (17%)

Query: 88  APPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMV------GTFNLP 141
           AP ++ L +GA   T         G  PGT  P  +   R A + V +           P
Sbjct: 150 APKRSALSAGARRDTS--------GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201

Query: 142 SDGSAVDVHINMEQAPIQSEPRVRLVM---------AQHMIRDIQTLLSRMECRGGPQPQ 192
           ++G    V    E +  +  P  R            A   +    T LS    R GP  +
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS-PARSGPSAR 260

Query: 193 HSQPPPQPPAVTPEPVALSS----QTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
            +   P  P+  P+P  L +    Q + P +  AP   P+ +          +P  TP P
Sbjct: 261 GTPRAPAHPS-QPKPKGLQALRPPQVTPPRKDAAPALGPLSS----------SPLATPSP 309

Query: 249 APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHE 308
           + A  + AP T      S +   ++   L        P      + L +   T       
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP--SPSAPPSLQTLPSPPATP------ 361

Query: 309 GREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVR------PMSHYTTPM 362
                Q   +L   +L+   ++F+    L   LA  PP+    +       P S   +P 
Sbjct: 362 ---PSQATTSLGSPTLQAT-HSFLPSPPLS-PLATPPPQAPPALALPPLQAPPSPPASPP 416

Query: 363 VLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP---PPGPGQASSVAPSSTNVESSAE 419
           +   A    Q      V +      PPP+P  +AP   P  P  + S  P S    S A 
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA- 475

Query: 420 GAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGP-PGH 478
            APP    P P  S P     +     P  +    +Q +   P   P+  T PL   P  
Sbjct: 476 -APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 534

Query: 479 GQTLGQQVPGFPTAPTRVVIARPTPPQARP-------SHPGGPPVSGTLQGAGLGTNASL 531
             +   Q P  P+A   +      PPQA P         P  PP S TLQ          
Sbjct: 535 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 594

Query: 532 AQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASAS-----AGTTNTATT--------- 577
              VSG        P L     PG  PPP+ + +S       AG +++AT+         
Sbjct: 595 DTSVSG--------PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD 646

Query: 578 AGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFL 637
           +GP  G  A PPP      A+L          GPA P A      +P     +P  PA  
Sbjct: 647 SGPEGGAAASPPPD-----AELAACHPAAWSRGPAPPLAFRGAPGAP-----LPWPPATG 696

Query: 638 QGMTDFLQAT-QTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPE--- 693
            G  D L    +T  P    P P    P     P PG+  G A +  G G  S SP+   
Sbjct: 697 PGSADGLCTIYETEGPESATPAPGALDPG----PSPGTSGGKAAAGAGAGASSRSPKQAR 752

Query: 694 --------FFTSVVQGVLSS---LLGSLGARAGS 716
                      SVVQ +LS    L  + GA  GS
Sbjct: 753 LGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 786



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 98/379 (25%), Positives = 133/379 (35%), Gaps = 33/379 (8%)

Query: 387 RPP---PTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQ 443
           RPP   P     AP  GP  +S +A  S +    ++ APP  PA P ++S    +     
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ-APPTLPATPHSSSLTCQLATPLP 339

Query: 444 SVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPG----HGQTLGQQVPGFPTAPTRVVIA 499
              P      ++Q   + P   PS  T  LG P     H       +    T P +   A
Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 399

Query: 500 RPTPP-QARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAP 558
              PP QA PS P  PP+S     +    NA    ++          PV      P   P
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459

Query: 559 PPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQ---PSMADLQFSQLLGNLLGPAGPG 615
               AT  + A  +  A      P  PA PP +P    P  A    +     L  P  P 
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP--PP 517

Query: 616 AGGSGVASPTITVAMPGVPAFLQGMTDF-------LQATQTAPPPPPP---------PPP 659
                +A+P +  A+P  PA   G   F       +    T PP  PP         PP 
Sbjct: 518 QAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 576

Query: 660 PPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSES 719
           PP +P  Q    P +P       G     +L+P       +   S+L G     AG S S
Sbjct: 577 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP--DLAGHSSS 634

Query: 720 IAAFIQRLSGSSNIFEPGA 738
             +  + L G  +  E GA
Sbjct: 635 ATSTPEELRGYDSGPEGGA 653



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 106/457 (23%), Positives = 143/457 (31%), Gaps = 86/457 (18%)

Query: 197 PPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP-------- 248
           PP  P  TP P A  +    P++  APP  P         +P  +P  TP P        
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQ--APPSPPA--------SPPLSPLATPSPQAPNALAV 433

Query: 249 ----APAGPTPAPETNAPNHP--SPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTD 302
               AP  P P+P   AP  P  SP          Q   S   P LQ     +  +    
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-----VPPSPPAS 488

Query: 303 YNNNHEGREEDQRLINLVGESLRLLG---NTFVALSDLRCNLACTPPRHLHVVRPMSHYT 359
              +       Q    L    L+L         AL+        +PP       P S   
Sbjct: 489 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548

Query: 360 TPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP--PPGPGQASSVAPSSTNVESS 417
           +  +   A  P Q        +      PP +P  +AP  PP PG  +SV  S   +  +
Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV--SGPRLTLA 606

Query: 418 AEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPG 477
               PPP P+  P+++        H S        +   DSG + G   S P        
Sbjct: 607 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD------ 660

Query: 478 HGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGG----PPVSGTLQGAGLGTNASLAQ 533
                 +     P A +R     P PP A    PG     PP +G     GL T      
Sbjct: 661 -----AELAACHPAAWSR----GPAPPLAFRGAPGAPLPWPPATGPGSADGLCT------ 705

Query: 534 MVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQ 593
                        +   +G     P P       S GT+     AG   G  ++ P   Q
Sbjct: 706 -------------IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP--KQ 750

Query: 594 PSMADLQFSQLLGN----------LLGPAGPGAGGSG 620
             + +L    L  +          LL  A   AGGSG
Sbjct: 751 ARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 787



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 46/197 (23%), Positives = 60/197 (30%), Gaps = 28/197 (14%)

Query: 501 PTPPQA-RPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPP 559
           P PP + RP  P  P     L  AG      LA+   G+ G  +          P  AP 
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI----------PESAPR 76

Query: 560 PAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGS 619
             P T SA   + N A+   PA G   + PP    S   +           P   G  G 
Sbjct: 77  AGP-TRSAGTSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134

Query: 620 GVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPP---------------PPPAP 664
            +++           A  +          T+ P P  P P               P PAP
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 194

Query: 665 EQQTMPPPGSPSGGAGS 681
             +  PP   P     S
Sbjct: 195 SARPRPPTEGPRKSVSS 211



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 77/325 (23%), Positives = 112/325 (34%), Gaps = 60/325 (18%)

Query: 422 PPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAP-TGPLGPPGHGQ 480
           PP  P PPP                PV    + +  +    G  P A   G +G    G 
Sbjct: 29  PPGSPRPPP----------------PVTPAALRVLGAAGAVGRKPLAERAGGIG----GA 68

Query: 481 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPG----GPPVSGTLQGAGLGTNASLAQMVS 536
           T+ +  P     PTR        P +RP   G     PP   T  G       +      
Sbjct: 69  TIPESAPR--AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126

Query: 537 GLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSM 596
           G +GQ  ++         G A   AP  ++ SAG      T+GP PG       TP P+M
Sbjct: 127 GPLGQKGLRISAEETVARGKATE-APKRSALSAGARRD--TSGPTPG-------TPSPAM 176

Query: 597 ADLQFSQLLGNLLG---PA----------GPGAGGSGVASPTITVAMPGV---PAFLQGM 640
           A  + S+  G  +G   PA          GP    S  +  + T   P     P+   G+
Sbjct: 177 A--RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234

Query: 641 TDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQ 700
                 + ++   P   P       + T   P  PS     P   GL++L P   T   +
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS----QPKPKGLQALRPPQVTPPRK 290

Query: 701 GVLSSLLGSLGARAGSSESIAAFIQ 725
              +  LG L +   ++ S +A +Q
Sbjct: 291 DA-APALGPLSSSPLATPSPSAALQ 314



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 40/145 (27%), Positives = 52/145 (35%), Gaps = 11/145 (7%)

Query: 561 APATASASAGTTNTATTAGPAPGGPAQPPPTPQP-SMADLQFSQLLGNLLGPAGPGAGGS 619
           A A A+A            P P G  +PPP   P ++  L  +  +G    P    AGG 
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGR--KPLAERAGGI 65

Query: 620 GVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSG-- 677
           G A  TI  + P         T    +   A  PP         P + T P P S  G  
Sbjct: 66  GGA--TIPESAPRAGPTRSAGT---SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120

Query: 678 -GAGSPGGLGLESLSPEFFTSVVQG 701
            G   PG LG + L      +V +G
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARG 145


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 92/354 (25%), Positives = 120/354 (33%), Gaps = 65/354 (18%)

Query: 388 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVE- 446
           PPP P    PPP P       PS        + AP  G A P    +  + R+ + S   
Sbjct: 629 PPPPPPPPPPPPPPPPPPPPLPS--------QSAPSAGSAAPMFVKYSTITRLQNASQHS 680

Query: 447 --------PVVMMHMNIQDSG-TQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVV 497
                   P VM   +++      P GV   P  P  PP  G  + Q  P  P AP+   
Sbjct: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPA-PCAPSLPQ 739

Query: 498 IARPTPPQ-----------ARPSHPGGPPVSGTLQGAGLGTNASLAQMVS--GLVGQLLM 544
            + P PP            A P+ P  PP+      A L   A    +V+         +
Sbjct: 740 FSAPPPPLKIHQVQHITQVAPPTPPPPPPIP-----APLPPQAPPKPLVTIPAPTSTKTV 794

Query: 545 QPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPP-----------PTPQ 593
            PV V Q  P    PP P      A   +    + P P  P  PP           P P 
Sbjct: 795 APV-VTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS 853

Query: 594 P-SMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPP 652
           P S       Q+      P  P A  S    P      P  P  ++    +  ++   P 
Sbjct: 854 PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS 913

Query: 653 P-------------PPPPPPPPPAPEQQTMPPPGSPS-GGAGSPGGLGLESLSP 692
           P             PPPPP P PAP     PP  SP+   +GSPG    ++ SP
Sbjct: 914 PDFPPPPPESSLVFPPPPPSPVPAPPPPP-PPTASPTPDKSGSPGKKTSKTSSP 966



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 87/327 (26%), Positives = 113/327 (34%), Gaps = 48/327 (14%)

Query: 360 TPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAE 419
           TP V+Q  ++  QI V        NG  PPP P    PPP PG A +    +    S  +
Sbjct: 688 TPPVMQSQSVKPQILVPP------NGVVPPPPP--PPPPPTPGSAMAQLKPAPCAPSLPQ 739

Query: 420 GAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG 479
            + PP P       H  + +++  +  P              P  +P AP  P  PP   
Sbjct: 740 FSAPPPPLKIHQVQH--ITQVAPPTPPP--------------PPPIP-APLPPQAPPKPL 782

Query: 480 QTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLV 539
            T+         APT      P   QA P  P  P      Q A     AS         
Sbjct: 783 VTI--------PAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA---FPASYIPPSPPTP 831

Query: 540 GQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADL 599
              +  P L  Q +    PPP+P +   S         A   P     PPPTP P+M   
Sbjct: 832 PVPVPPPTLPKQQSFCAKPPPSPLSPVPSV----VKQIASQFP-----PPPTP-PAMESQ 881

Query: 600 QFSQLLGNLLGPAGPGAGGSGVASP-TITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPP 658
               +  N+   + P         P +I V  P  P      +        +P P PPPP
Sbjct: 882 PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941

Query: 659 PPPPA-PEQQTMPPPGSPSGGAGSPGG 684
           PPP A P       PG  +    SPGG
Sbjct: 942 PPPTASPTPDKSGSPGKKTSKTSSPGG 968



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 126/543 (23%), Positives = 166/543 (30%), Gaps = 100/543 (18%)

Query: 181  SRMECRGGPQPQHSQP-PPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPA 239
            +RME    P      P  PQP  VTP     +SQ S P+    PP  P            
Sbjct: 593  ARMESMNRPYTSLVPPLSPQPKIVTPYT---ASQPSPPLPPPPPPPPP------------ 637

Query: 240  QNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAA 299
                  P P P  P P P  +AP+  S A        + RL++  Q     +   L    
Sbjct: 638  -----PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQ-----HSGALFKPP 687

Query: 300  TTDYNNNHEGREEDQRLINLV-------------GESLRLLGNTFVALSDLRCNLACTPP 346
            T     +   + +     N V             G ++  L     A S L    A  PP
Sbjct: 688  TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPS-LPQFSAPPPP 746

Query: 347  RHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASS 406
              +H V+ ++    P       IP  +              P   P      P P    +
Sbjct: 747  LKIHQVQHITQVAPPTPPPPPPIPAPL-------------PPQAPPKPLVTIPAPTSTKT 793

Query: 407  VAPSSTNVESSAEGAPP-PGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGV 465
            VAP  T      + APP P P  PPA   P           P   + +       Q    
Sbjct: 794  VAPVVT------QAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFC 847

Query: 466  PSAPTGPLGP-PGHGQTLGQQVPGFPTAPT-RVVIARPTPPQARPSHPGGPPVSGTLQGA 523
               P  PL P P   + +  Q P  PT P       +P P    P  P  P V    +  
Sbjct: 848  AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP--PAVKAKPKWQ 905

Query: 524  GLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASAS---AGTTNTATTAGP 580
                               L+ P       P   PPP P TAS +   +G+    T+   
Sbjct: 906  PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA-PPPPPPPTASPTPDKSGSPGKKTSKTS 964

Query: 581  APGGPAQPPPTPQ-------------PSMADLQFSQLLGNLLGPAGPGAGGSGVASPTIT 627
            +PGG  +PPPTPQ             P         L+     PA  G+       P   
Sbjct: 965  SPGG-KKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA 1023

Query: 628  VAMPG--------VPAFLQGMTDFLQATQTA----------PPPPPPPPPPPPAPEQQTM 669
               PG        +P  LQ      +A   +          P PP     PPP PE +  
Sbjct: 1024 PPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP 1083

Query: 670  PPP 672
             PP
Sbjct: 1084 LPP 1086



 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 87/355 (24%), Positives = 110/355 (30%), Gaps = 37/355 (10%)

Query: 344  TPPRHLHVVRPMSHYTTPMVLQQAAIPIQIN-VGTTVTMTGNGTRPPPTPNAEA------ 396
            TPP    +  P+     P  L     P     V   VT     T  PP P A+       
Sbjct: 762  TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPA 821

Query: 397  ---PPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIR-ISHQSVEPVVMMH 452
               PP  P     V P +   + S    PPP P  P     P V++ I+ Q   P     
Sbjct: 822  SYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPV----PSVVKQIASQFPPPPTPPA 877

Query: 453  MNIQDSGTQPGGV--PSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQA---R 507
            M  Q     P  V   S P     P     ++    P FP  P    +  P PP +    
Sbjct: 878  MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937

Query: 508  PSHPGGPPVSGTLQGAGL-GTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATAS 566
            P  P  P  S T   +G  G   S      G       Q     + + G   P     + 
Sbjct: 938  PPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSV 997

Query: 567  ASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTI 626
             S  +  T      +P     PPP   P    L       NL G   PG    G  S   
Sbjct: 998  DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL-------NLSGVNLPGVLQQGCVSAKA 1050

Query: 627  TVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGS 681
             V        L G          +PP     PPPPP  E   +PP   P+  +G+
Sbjct: 1051 PV--------LSGRGKDSVVEFPSPPSDSDFPPPPPETE-LPLPPIEIPAVFSGN 1096



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 49/171 (28%), Positives = 59/171 (34%), Gaps = 55/171 (32%)

Query: 530 SLAQMVSGLVGQLLMQPVLV-----AQGTPGMAPPPAPATASASAGTTNTATTAGPAPGG 584
           S+ +  + LV  L  QP +V     +Q +P + PPP P                 P P  
Sbjct: 597 SMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPP----------------PPPPP 640

Query: 585 PAQPPPTPQPSMAD-------------------LQFSQLLGNLLGPAGPGAGGSGVASPT 625
           P  PPP P PS +                       SQ  G L  P  P    S    P 
Sbjct: 641 PPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQ 700

Query: 626 ITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPS 676
           I V   GV                 PPPPPPPPP P +   Q  P P +PS
Sbjct: 701 ILVPPNGV---------------VPPPPPPPPPPTPGSAMAQLKPAPCAPS 736



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 22/38 (57%), Positives = 24/38 (63%)

Query: 646 ATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPG 683
           A+Q +PP PPPPPPPPP P     PPP  PS  A S G
Sbjct: 621 ASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG 658



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 83/340 (24%), Positives = 110/340 (32%), Gaps = 84/340 (24%)

Query: 388  PPPTPNAEAPPPGPGQAS-----SVAPSSTNVESSAEGAPPPGPAPPPATS--------H 434
            PPP+P    PPP P  AS     S +P     ++S+ G   P P P   +S        H
Sbjct: 930  PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEH 989

Query: 435  PRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGF----- 489
            P   R    SV+ +V       +SG+        P  P   PG     G  +PG      
Sbjct: 990  PEPKR---PSVDSLVSKFTPPAESGSPSKETLPPPAAP-PKPGKLNLSGVNLPGVLQQGC 1045

Query: 490  -----PTAPTR---VVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQ 541
                 P    R    V+  P+PP      P  PP    L    +   A  +   S  V  
Sbjct: 1046 VSAKAPVLSGRGKDSVVEFPSPPSDSDFPP--PPPETELPLPPIEIPAVFSGNTSPKVAV 1103

Query: 542  LLMQPVLVAQGTPGMAPPPA-----PATASASAGTTNTATTAGPAPGGPAQPPP--TPQP 594
            +  QP   ++ +   APPP       +T    A  +   T A   P  P  P    + QP
Sbjct: 1104 VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP 1163

Query: 595  S-MADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPP 653
              +ADL    L    +   G  +     A PT T+                     A PP
Sbjct: 1164 GFLADLN-RTLQRKSITRHGSLSSRMSRAEPTATM------------------DDMALPP 1204

Query: 654  PPP-------------------------PPPPPPAPEQQT 668
            PPP                         PPP PP  +Q T
Sbjct: 1205 PPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNT 1244



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 43/173 (24%), Positives = 70/173 (40%), Gaps = 26/173 (15%)

Query: 926  GPDAILRYVRRVGD----PPQP---LPEEPMEVQGAERASPEPQRENASPAPGTTAEEAM 978
            G D+++ +     D    PP P   LP  P+E+      +  P+    +P P   ++ ++
Sbjct: 1057 GKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSV 1116

Query: 979  SRGPPPA-PEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYL 1037
             + PPP  P+         A    +P  A V    VP +    +S   V+P       +L
Sbjct: 1117 KKAPPPTRPKRNDSTRLTQAEISEQPTMATV----VPQVPTSPKSSLSVQP------GFL 1166

Query: 1038 SGM-PAKRRKTMQGEGPQLLLSEAVSRAAKAAG----ARPLTSPESLSRDLEA 1085
            + +    +RK++   G    LS  +SRA   A     A P   PE LS   +A
Sbjct: 1167 ADLNRTLQRKSITRHGS---LSSRMSRAEPTATMDDMALPPPPPELLSDQQKA 1216



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 16/41 (39%), Positives = 17/41 (41%)

Query: 654 PPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEF 694
           P PP PPPP P     PPP  P     S       S +P F
Sbjct: 624 PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 37/169 (21%), Positives = 64/169 (37%), Gaps = 21/169 (12%)

Query: 940  PPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEG--GSRDEQDGA 997
            PP P P  P+      +A P+P     +P    T    +++  PP P        +Q   
Sbjct: 760  PPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819

Query: 998  SAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRK----------- 1046
             A   P +   PP  VP+    +  Q+    +PP S   LS +P+  ++           
Sbjct: 820  PASYIPPSPPTPP--VPVPPPTLPKQQSFCAKPPPSP--LSPVPSVVKQIASQFPPPPTP 875

Query: 1047 -TMQGEGPQLLLSEAVSRAAKAAGARPLTSPESL---SRDLEAPEVQES 1091
              M+ +  + + +    ++  A  A+P   P S+   S D   P  + S
Sbjct: 876  PAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 8/67 (11%)

Query: 940  PPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRG---PPPAPEGGSRDEQDG 996
            PP P+P  P        ASP P +   S +PG    +  S G   PPP P+  S  +   
Sbjct: 931  PPSPVPAPPPPPPPT--ASPTPDK---SGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS 985

Query: 997  ASAETEP 1003
             +   EP
Sbjct: 986  GAEHPEP 992


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 93/306 (30%), Positives = 111/306 (36%), Gaps = 78/306 (25%)

Query: 388 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPA-----TSHPRVIRISH 442
           PPP P   APPP P    S  P ST+  SS   A P G +   A     T   +V +I+ 
Sbjct: 12  PPPPPPLGAPPPPP---PSAPPVSTDT-SSLRRADPKGRSALLADIQQGTRLRKVTQIND 67

Query: 443 QSVEPVVMMHMNIQDSGTQPGGVPSAPT-GPLGPPGHGQTLGQQVPGFPTAPTRVVIARP 501
           +S   +          GT   G  SA T G   PP  G        GFP       + RP
Sbjct: 68  RSAPQIE------SSKGTNKEGGGSANTRGASTPPTLGDLFAG---GFP-------VLRP 111

Query: 502 TPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPA 561
                     G   V+G   G G G+ A                P L  +   G   PPA
Sbjct: 112 A---------GQRDVAGGKTGQGPGSRAP--------------SPRLPNKTISGPLIPPA 148

Query: 562 PATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADL-----QFSQLLGNLLGPAGPGA 616
                 ++     A TA P P  PA PPPTP P    L       S +   L+ P GP  
Sbjct: 149 SPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLT 208

Query: 617 GGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPS 676
            G+      + V  P VP               APPPPPPPPPP P P    +PP    S
Sbjct: 209 KGN------LPVVAPPVPC--------------APPPPPPPPPPTPPP----LPPASVLS 244

Query: 677 GGAGSP 682
             A  P
Sbjct: 245 DKAVKP 250



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 83/320 (25%), Positives = 97/320 (30%), Gaps = 65/320 (20%)

Query: 370 PIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPP 429
           P    +G T    G     PP PN  APPP                      PPP P PP
Sbjct: 147 PASPRLGNTSEAHGAARTAPPRPNVPAPPP------------------PTPPPPPPPLPP 188

Query: 430 PATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGF 489
           P          S   ++  ++        G  P   P  P  P  PP         +P  
Sbjct: 189 PLP--------SSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLP-- 238

Query: 490 PTAPTRVVIARPTPPQARPSH-PGGPPVSGTLQGAGL-GTNASLAQMVSGLVGQLLMQPV 547
              P  V+  +   PQ  P H P  PP    L   G  G  A  A             P 
Sbjct: 239 ---PASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA------------SPA 283

Query: 548 LVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPG---GPAQPPPTPQPSMADLQFSQL 604
             AQ  P   PPP P  AS S      +  A P PG       PPP P  S +     Q 
Sbjct: 284 QDAQEPPA-PPPPLPPYASCS---PRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK 339

Query: 605 LGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAP 664
            G    PA P   GS    P +     G P    G  +          PPP PP   P  
Sbjct: 340 AGAQALPAPPAPPGS---QPFLQKKRHGRPGAGGGKLN----------PPPAPPARSPTT 386

Query: 665 EQQTMPPPGSPSGGAGSPGG 684
           E  +     +       PGG
Sbjct: 387 ELSSKSQQATAWTPTQQPGG 406



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 58/215 (26%), Positives = 79/215 (36%), Gaps = 41/215 (19%)

Query: 487 PGFPTAPTRVVIARPTPPQARPSHPGGPPVS---GTLQGAG-LGTNASLAQMVSGLVGQL 542
           P  P  P    +  P PP      P  PPVS    +L+ A   G +A LA +  G     
Sbjct: 7   PPPPLPPPPPPLGAPPPPP-----PSAPPVSTDTSSLRRADPKGRSALLADIQQGT---- 57

Query: 543 LMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAP------GGPAQPPPTPQPSM 596
            ++ V             +  T     G+ NT   + P        GG     P  Q  +
Sbjct: 58  RLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDV 117

Query: 597 ADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAF---LQGMTDFLQATQTAPP- 652
           A  +  Q         GPG+       P  T++ P +P     L   ++   A +TAPP 
Sbjct: 118 AGGKTGQ---------GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPR 168

Query: 653 -----PPPPPPPPPPAPEQQTMPPPGSPSGGAGSP 682
                PPPP PPPPP P    +PPP   S    +P
Sbjct: 169 PNVPAPPPPTPPPPPPP----LPPPLPSSSPIKTP 199



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 19/43 (44%), Positives = 20/43 (46%)

Query: 651 PPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPE 693
           P PPPPPPP PP P     PPP  PS    S     L    P+
Sbjct: 2   PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPK 44



 Score = 39.7 bits (91), Expect = 0.016
 Identities = 47/189 (24%), Positives = 67/189 (35%), Gaps = 24/189 (12%)

Query: 80  KVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFN 139
           KV  + +R+ PQ     G +   G ++ T G  +PP T G             +  G F 
Sbjct: 61  KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPP-TLGD------------LFAGGFP 107

Query: 140 LPSDGSAVDVHINME-QAPIQSEPRVRL---VMAQHMIRDIQTLLSRM-ECRGG-----P 189
           +       DV      Q P    P  RL    ++  +I      L    E  G      P
Sbjct: 108 VLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP 167

Query: 190 QPQHSQPPPQPPAVTPEPVALSSQTSEPVESE-APPREPMEAEEVEERAPAQNPELTPGP 248
           +P    PPP  P   P P+     +S P+++    P  P+    +   AP       P P
Sbjct: 168 RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP 227

Query: 249 APAGPTPAP 257
            P  PTP P
Sbjct: 228 PPPPPTPPP 236



 Score = 38.1 bits (87), Expect = 0.047
 Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 18/97 (18%)

Query: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSE-------------PVESEAPPREP-----MEA 230
           P P    PPP PP  TP P+  +S  S+             P+    P   P     ++A
Sbjct: 218 PVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKA 277

Query: 231 EEVEERAPAQNPELTPGPAPAGPTPAPETNAPNHPSP 267
           E       AQ P   P P P   + +P  + P  P P
Sbjct: 278 EPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLP 314


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 85/311 (27%), Positives = 106/311 (34%), Gaps = 63/311 (20%)

Query: 395 EAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPAT-----SHPRVIRISHQSVEPVV 449
           EAP P     S+  P++T + S+   A P    PPP+      S P  +        P  
Sbjct: 322 EAPVPA-SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380

Query: 450 MMHMNIQDSGTQPGGVPSAPTG-----PLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPP 504
            MH      G  PGG    P       P    GHG    Q  P  P  P    +  P PP
Sbjct: 381 GMH------GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPW---MQPPPPP 431

Query: 505 QAR----PSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPP 560
             +    P H G PP+   L    +G+         G++    M          GM PPP
Sbjct: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM----------GMMPPP 481

Query: 561 APATASASAGTTNTATTAGPAPGGPA--------QPPPTPQPSMA-----DLQFSQLLGN 607
            P  +              P P GP         QPPP P PS +      L + Q    
Sbjct: 482 PPPPSGQPP----------PPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531

Query: 608 LLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPP-----PPPPPPPPP 662
               AG G+            A PG P  +QG    +       PP     PPPPPPPPP
Sbjct: 532 TTTSAGTGSIPPWQQQQAAAAASPGAPQ-MQGNPTMVPLPPGVQPPLPPGAPPPPPPPPP 590

Query: 663 APEQQTMPPPG 673
                 +PP G
Sbjct: 591 GSAGMMIPPRG 601



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 70/261 (26%), Positives = 85/261 (32%), Gaps = 62/261 (23%)

Query: 466 PSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSH------PGGPPVSGT 519
           P+AP     PP    T   + P   + P+          ++RP H      PGGP     
Sbjct: 346 PAAPANNPPPPSLMSTTQSRPPWMNSGPS----------ESRPYHGMHGGGPGGP----- 390

Query: 520 LQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAG 579
             G G  +       ++G  G   MQ        P M PPP P                G
Sbjct: 391 --GGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ-------------G 435

Query: 580 PAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGA----GGSGVASPTITVAMPGVPA 635
           P P G   PPP            Q LG+   P G G      G G+  P     MP  P 
Sbjct: 436 PHPPGHHGPPP----------MDQYLGST--PVGSGVYRLHQGKGMMPPPPMGMMPPPPP 483

Query: 636 FLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFF 695
              G           PPPPP  P PP   +QQ  PPP  PS    S   L  +  +    
Sbjct: 484 PPSGQ----------PPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTT 533

Query: 696 TSVVQGVLSSLLGSLGARAGS 716
           TS   G +        A A S
Sbjct: 534 TSAGTGSIPPWQQQQAAAAAS 554



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 49/180 (27%), Positives = 61/180 (33%), Gaps = 24/180 (13%)

Query: 345 PPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQA 404
           PP +     P  H   PM     + P+    G      G G  PPP      PPP P   
Sbjct: 430 PPMNQGPHPPGHHGPPPMDQYLGSTPV--GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSG 487

Query: 405 SSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGG 464
               P S  +    +    P P PPP++S      +  Q            Q++ T    
Sbjct: 488 QPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQ------------QNTTTT--- 532

Query: 465 VPSAPTGPLGPPGHGQTLGQQVPGFPTA---PTRVV----IARPTPPQARPSHPGGPPVS 517
             SA TG + P    Q      PG P     PT V     +  P PP A P  P  PP S
Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS 592



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 26/103 (25%), Positives = 36/103 (34%), Gaps = 10/103 (9%)

Query: 585 PAQPPPTPQPSMADLQFSQL---LGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMT 641
           P  P      +  D ++  L   LG    PA  G+      +P  +   P  PA      
Sbjct: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPP 356

Query: 642 DFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGG 684
             +  TQ+ PP     P        ++ P  G   GG G PGG
Sbjct: 357 SLMSTTQSRPPWMNSGP-------SESRPYHGMHGGGPGGPGG 392



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 25/93 (26%), Positives = 31/93 (33%), Gaps = 13/93 (13%)

Query: 188 GPQPQHSQPPPQPPAVTPEPVALSSQTSEPVE-------------SEAPPREPMEAEEVE 234
           GP P   Q   QPP   P   +++S T  P +             S  P ++   A    
Sbjct: 495 GPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAAS 554

Query: 235 ERAPAQNPELTPGPAPAGPTPAPETNAPNHPSP 267
             AP      T  P P G  P     AP  P P
Sbjct: 555 PGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP 587


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 95/341 (27%), Positives = 118/341 (34%), Gaps = 80/341 (23%)

Query: 395 EAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPAT-----SHPRVIRISHQSVEPVV 449
           EAP P     S+  P++T + S+   A P    PPP+      S P  +        P  
Sbjct: 322 EAPVPA-SVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYH 380

Query: 450 MMHMNIQDSGTQPGGVPSAPTG-----PLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPP 504
            MH      G  PGG    P       P    GHG    Q  P  P  P    +  P PP
Sbjct: 381 GMH------GGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPW---MQPPPPP 431

Query: 505 QAR----PSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPP 560
             +    P H G PP+   L    +G+         G++    M          GM PPP
Sbjct: 432 MNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM----------GMMPPP 481

Query: 561 APATASASAGTTNTATTAGPAPGGPA--------QPPPTPQPSMA-----DLQFSQLLGN 607
            P  +              P P GP         QPPP P PS +      L + Q    
Sbjct: 482 PPPPSGQPP----------PPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTT 531

Query: 608 LLGPAGPGAGGSGVASPTITVAMPGVPAFLQG---MTDFLQATQT-----APPPPPPPPP 659
               AG G+            A PG P  +QG   M       Q      APPPPPPPPP
Sbjct: 532 TTTSAGTGSIPPWQQQQAAAAASPGAPQ-MQGNPTMVPLPPGVQPPLPPGAPPPPPPPPP 590

Query: 660 --------PPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSP 692
                   PPP P     PPP  PS    +  G+G+  + P
Sbjct: 591 GSAGMMYAPPPPP-----PPPMDPSNFV-TMMGMGVAGMPP 625



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 67/258 (25%), Positives = 82/258 (31%), Gaps = 58/258 (22%)

Query: 345 PPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQA 404
           PP +     P  H   PM     + P+    G      G G  PPP      PPP P   
Sbjct: 430 PPMNQGPHPPGHHGPPPMDQYLGSTPV--GSGVYRLHQGKGMMPPPPMGMMPPPPPPPSG 487

Query: 405 SSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGG 464
               P S  +    +    P P PPP++S      +  Q            Q++ T    
Sbjct: 488 QPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQ------------QNTTTT--- 532

Query: 465 VPSAPTGPLGPPGHGQTLGQQVPGFPTA---PTRVV----IARPTPPQARPSHPGGPPVS 517
             SA TG + P    Q      PG P     PT V     +  P PP A P  P  PP  
Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPP-- 590

Query: 518 GTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATT 577
                              G  G +   P           PPP P    ++  T      
Sbjct: 591 -------------------GSAGMMYAPP-----------PPPPPPMDPSNFVTMMGMGV 620

Query: 578 AGPAPGG--PAQPPPTPQ 593
           AG  P G  PA PPP PQ
Sbjct: 621 AGMPPFGMPPAPPPPPPQ 638



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 70/261 (26%), Positives = 85/261 (32%), Gaps = 62/261 (23%)

Query: 466 PSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSH------PGGPPVSGT 519
           P+AP     PP    T   + P   + P+          ++RP H      PGGP     
Sbjct: 346 PAAPANNPPPPSLMSTTQSRPPWMNSGPS----------ESRPYHGMHGGGPGGP----- 390

Query: 520 LQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAG 579
             G G  +       ++G  G   MQ        P M PPP P                G
Sbjct: 391 --GGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQ-------------G 435

Query: 580 PAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGA----GGSGVASPTITVAMPGVPA 635
           P P G   PPP            Q LG+   P G G      G G+  P     MP  P 
Sbjct: 436 PHPPGHHGPPP----------MDQYLGST--PVGSGVYRLHQGKGMMPPPPMGMMPPPPP 483

Query: 636 FLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFF 695
              G           PPPPP  P PP   +QQ  PPP  PS    S   L  +  +    
Sbjct: 484 PPSGQ----------PPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTT 533

Query: 696 TSVVQGVLSSLLGSLGARAGS 716
           TS   G +        A A S
Sbjct: 534 TSAGTGSIPPWQQQQAAAAAS 554



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 26/103 (25%), Positives = 36/103 (34%), Gaps = 10/103 (9%)

Query: 585 PAQPPPTPQPSMADLQFSQL---LGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMT 641
           P  P      +  D ++  L   LG    PA  G+      +P  +   P  PA      
Sbjct: 297 PGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSGPATTPLASAPRPAAPANNPPPP 356

Query: 642 DFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGG 684
             +  TQ+ PP     P        ++ P  G   GG G PGG
Sbjct: 357 SLMSTTQSRPPWMNSGP-------SESRPYHGMHGGGPGGPGG 392



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 25/93 (26%), Positives = 31/93 (33%), Gaps = 13/93 (13%)

Query: 188 GPQPQHSQPPPQPPAVTPEPVALSSQTSEPVE-------------SEAPPREPMEAEEVE 234
           GP P   Q   QPP   P   +++S T  P +             S  P ++   A    
Sbjct: 495 GPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAAS 554

Query: 235 ERAPAQNPELTPGPAPAGPTPAPETNAPNHPSP 267
             AP      T  P P G  P     AP  P P
Sbjct: 555 PGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPP 587



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 19/67 (28%), Positives = 22/67 (32%)

Query: 189 PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
           P  Q   PP  PP   P P   +     P     PP +P     +     A  P     P
Sbjct: 571 PGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPP 630

Query: 249 APAGPTP 255
           AP  P P
Sbjct: 631 APPPPPP 637



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 28/104 (26%), Positives = 35/104 (33%), Gaps = 26/104 (25%)

Query: 190 QPQHSQPPPQPP------AVTPEPVA--LSSQTSEPVESEAPPREPMEAEEVEERA---- 237
           Q Q  QPPP PP      + TP P     ++ T+       PP +  +A           
Sbjct: 501 QQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQM 560

Query: 238 ----------PAQNPELTPGPAPAGPTPAPET----NAPNHPSP 267
                     P   P L PG  P  P P P +     AP  P P
Sbjct: 561 QGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPP 604


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 106/369 (28%), Positives = 134/369 (36%), Gaps = 64/369 (17%)

Query: 388 PPPTPNAEA---PPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS 444
           PPP+P  +A   PP  P  + S  P S    S A  APP    P P  S P     +   
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA--APPLQVPPSPPASPPMSPSATPPP 460

Query: 445 VEPVVMMHMNIQDSGTQPGGVPSAPTGPL-GPPGHGQTLGQQVPGFPTAPTRVVIARPTP 503
             P  +    +Q +   P   P+  T PL   P    +   Q P  P+A   +      P
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 504 PQARP-------SHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGM 556
           PQA P         P  PP S TLQ             VSG        P L     PG 
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG--------PRLTLALAPGP 572

Query: 557 APPPAPATASA-----SAGTTNTATT---------AGPAPGGPAQPPPTPQPSMADLQFS 602
            PPP+ + +S       AG +++AT+         +GP  G  A PPP      A+L   
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD-----AELAAC 627

Query: 603 QLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFL-QATQTAPPPPPPPPPPP 661
                  GPA P A      +P     +P  PA   G  D L    +T  P    P P  
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAP-----LPWPPATGPGSADGLCTIYETEGPESATPAPGA 682

Query: 662 PAPEQQTMPPPGSPSGGAGSPGGLGLESLSPE-----------FFTSVVQGVLSS---LL 707
             P     P PG+  G A +  G G  S SP+              SVVQ +LS    L 
Sbjct: 683 LDPG----PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLA 738

Query: 708 GSLGARAGS 716
            + GA  GS
Sbjct: 739 AAEGAAGGS 747



 Score = 70.9 bits (172), Expect = 7e-12
 Identities = 94/374 (25%), Positives = 125/374 (33%), Gaps = 34/374 (9%)

Query: 392 PNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPP---PATSHPRVIRISHQSVEPV 448
           P+A   P  P   S   P         +  PP   A P   P +S P  +     S  P 
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP--LATPSPSAPPS 305

Query: 449 VMMHMNIQDSGTQPGGVPSAPTGPLGPPG----HGQTLGQQVPGFPTAPTRVVIARPTPP 504
                ++Q   + P   PS  T  LG P     H       +    T P +   A   PP
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365

Query: 505 -QARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPA 563
            QA PS P  PP+S     +    NA    ++          PV      P   P    A
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425

Query: 564 TASASAGTTNTATTAGPAPGGPAQPPPTPQ---PSMADLQFSQLLGNLLGPAGPGAGGSG 620
           T  + A  +  A      P  PA PP +P    P  A    +     L  P  P      
Sbjct: 426 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP--PPQAPPA 483

Query: 621 VASPTITVAMPGVPAFLQGMTDF-------LQATQTAPPPPPP---------PPPPPPAP 664
           +A+P +  A+P  PA   G   F       +    T PP  PP         PP PP +P
Sbjct: 484 LATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 542

Query: 665 EQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFI 724
             Q    P +P       G     +L+P       +   S+L G     AG S S  +  
Sbjct: 543 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP--DLAGHSSSATSTP 600

Query: 725 QRLSGSSNIFEPGA 738
           + L G  +  E GA
Sbjct: 601 EELRGYDSGPEGGA 614



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 85/332 (25%), Positives = 115/332 (34%), Gaps = 61/332 (18%)

Query: 388 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
           P P P+A   PP  G   SV  SS +  S+ E +P     P   ++   + R + +S+  
Sbjct: 181 PRPAPSARPRPPTEGPRKSV--SSASEHSTTEPSPAARRRP---SAGGGLQRPASRSLSS 235

Query: 448 VVMMHMNIQDSGTQPGGVPSAPTGPLGP-------------------------PGHGQTL 482
                 +   SG    G P AP  P  P                         P     L
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 295

Query: 483 GQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQL 542
               P  P +P     + P   Q  PS P  PP   T         A+ + + S  +  L
Sbjct: 296 ATPSPSAPPSP-----SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350

Query: 543 LMQPVLVAQGTPGMAPPP--APATASASAGTTNTATTAGPAPG--------GPAQPPPTP 592
              P    Q  P +A PP  AP +  AS   +  AT +  AP          P  PPP+P
Sbjct: 351 ATPP---PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407

Query: 593 QPSMADLQFSQLLGNLLGPAG--PGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTA 650
                   FS      + P+   P      +A+P + V  P  PA           + +A
Sbjct: 408 P---VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPA-------SPPMSPSA 456

Query: 651 PPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSP 682
            PPP  PPP    P Q   PPP +P   A  P
Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 488



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 82/306 (26%), Positives = 102/306 (33%), Gaps = 46/306 (15%)

Query: 399 PGPGQASSVAPSSTNVESSAEGAPPPGPA--PPPATSHPRVIRIS---HQSVEPVVMMHM 453
           P PG  S      +    +  G P P P+  P P T  PR    S   H + EP      
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217

Query: 454 NIQDSG--TQPGGVP-SAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARP------TPP 504
                G   +P     S+   PL  P      G    G P AP      +P       PP
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARS---GPSARGTPRAPAHPSQPKPKGLQALRPP 274

Query: 505 QARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPAT 564
           Q  P      P  G L  + L T +  A         L   P          A PP+ AT
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP-------SPPATPPSQAT 327

Query: 565 ASASAGTTNTATTAGPAP--GGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVA 622
            S  + T     +  P+P     A PPP   P++A       L  L  P  P A     +
Sbjct: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA-------LPPLQAPPSPPA-----S 375

Query: 623 SPTITVAMPGVPAFLQGMTDFLQATQTAPPPPP------PPPPPPPAPEQQTMPPPGSPS 676
            P   +A P   A        LQA  + PP PP      PP  PP +P     PP  +P 
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP--SATPPSQAPP 433

Query: 677 GGAGSP 682
             A  P
Sbjct: 434 SLAAPP 439



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 106/457 (23%), Positives = 142/457 (31%), Gaps = 86/457 (18%)

Query: 197 PPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP-------- 248
           PP  P  TP P A  +    P++  APP  P         +P  +P  TP P        
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQ--APPSPPA--------SPPLSPLATPSPQAPNALAV 394

Query: 249 ----APAGPTPAPETNAPNHP--SPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTD 302
               AP  P P+P   AP  P  SP          Q   S   P LQ     +  +    
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-----VPPSPPAS 449

Query: 303 YNNNHEGREEDQRLINLVGESLRLL---GNTFVALSDLRCNLACTPPRHLHVVRPMSHYT 359
              +       Q    L    L+L         AL+        +PP       P S   
Sbjct: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509

Query: 360 TPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP--PPGPGQASSVAPSSTNVESS 417
           +  +   A  P Q        +      PP +P  +AP  PP PG  +SV+     +  +
Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 569

Query: 418 AEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPG 477
               PPP  +P    S P +    H S        +   DSG + G   S P        
Sbjct: 570 PGPPPPPSRSPSSTLSGPDL--AGHSSSATSTPEELRGYDSGPEGGAAASPPPD------ 621

Query: 478 HGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGG----PPVSGTLQGAGLGTNASLAQ 533
                 +     P A +R     P PP A    PG     PP +G     GL T      
Sbjct: 622 -----AELAACHPAAWSR----GPAPPLAFRGAPGAPLPWPPATGPGSADGLCT------ 666

Query: 534 MVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQ 593
                        +   +G     P P       S GT+     AG   G  ++ P   Q
Sbjct: 667 -------------IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP--KQ 711

Query: 594 PSMADLQFSQLLGN----------LLGPAGPGAGGSG 620
             + +L    L  +          LL  A   AGGSG
Sbjct: 712 ARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSG 748



 Score = 38.1 bits (87), Expect = 0.047
 Identities = 48/199 (24%), Positives = 66/199 (33%), Gaps = 20/199 (10%)

Query: 501 PTPPQA-RPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPP 559
           P PP + RP  P  P     L  AG      LA+   G+ G  + +    A G    + P
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA-GPTRTSRP 85

Query: 560 PAPATASASAGTTNTATTAGPAPG---GPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGA 616
           PA      +    NT+     +PG   G  +P P  Q  +       +       A   +
Sbjct: 86  PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145

Query: 617 GGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPP---PPPPPPAPEQQ------ 667
             S  A    +   PG P+           T+   P P P   P PP   P +       
Sbjct: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205

Query: 668 ---TMPPPGS---PSGGAG 680
              T P P +   PS G G
Sbjct: 206 HSTTEPSPAARRRPSAGGG 224



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 6/96 (6%)

Query: 940  PPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASA 999
            P  P   +P  +Q        P R++A+PA G  +   ++   P AP   S       S 
Sbjct: 257  PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP----PSL 312

Query: 1000 ETEPWAAAVPPE--WVPIIQQDIQSQRKVKPQPPLS 1033
            +T P   A PP      +    +Q+     P PPLS
Sbjct: 313  QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 348



 Score = 33.9 bits (76), Expect = 0.89
 Identities = 24/90 (26%), Positives = 35/90 (38%), Gaps = 5/90 (5%)

Query: 191 PQHSQPPPQPPAVTPEPVALSSQTSEPVE-SEAPPREPMEAEEVEERAPAQNPELTPGPA 249
           P     PP  P+ TP P A     + P++ ++ PP+ P        +A    P   PG A
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 503

Query: 250 PAGPTP----APETNAPNHPSPAEYVEVLQ 275
           P  P+     +P    P    P     +LQ
Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 41/145 (28%), Positives = 54/145 (37%), Gaps = 20/145 (13%)

Query: 561 APATASASAGTTNTATTAGPAPGGPAQPPPTPQP-SMADLQFSQLLGNLLGPAGPGAGGS 619
           A A A+A            P P G  +PPP   P ++  L  +  +G    P    AGG 
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGR--KPLAERAGGI 65

Query: 620 GVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSG-- 677
           G A  TI  + P               T+T+ PP        P P + T P P S  G  
Sbjct: 66  GGA--TIPESAPRA-----------GPTRTSRPPASGRGERAP-PAKNTSPGPVSSPGRA 111

Query: 678 -GAGSPGGLGLESLSPEFFTSVVQG 701
            G   PG LG + L      +V +G
Sbjct: 112 SGTTRPGPLGQKGLRISAEETVARG 136



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 24/83 (28%), Positives = 34/83 (40%), Gaps = 7/83 (8%)

Query: 189 PQPQHSQPPPQ-PPAVTPEPVAL--SSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           P  Q ++PPPQ PPA+   P+    S   S P ++   P   +    +    P Q P + 
Sbjct: 469 PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL-ATPPPQAPPVL 527

Query: 246 PGP---APAGPTPAPETNAPNHP 265
             P    P  P  +P   AP  P
Sbjct: 528 AAPLLQVPPSPPASPTLQAPRRP 550


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 114/425 (26%), Positives = 141/425 (33%), Gaps = 73/425 (17%)

Query: 334 LSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINV--GTTVTMTGNGTRPP-- 389
           +  L   LA +   H H+        TP V   AA  +  +V  G+     G G   P  
Sbjct: 26  VGSLESQLAASAAHHHHLAP-----RTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAE 80

Query: 390 --PTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
             P    E PP G  +     P      S      P GPAPP A   P     S  S  P
Sbjct: 81  GAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPP-EGSAGSCAP 139

Query: 448 VVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQAR 507
           V         +     G   AP GP  P G      +  PG    P          P   
Sbjct: 140 V-------PAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP-------GPGPGPG 185

Query: 508 PSHPGGPPVSGTLQGAGLGTN-----ASLAQMVSGLVGQLLMQPVLVAQGT-------PG 555
           P  P GP  + TL G+    N     A    +V+     LL  P   A GT        G
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVG 245

Query: 556 MAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPG 615
            A PPAPA  S           A PAP  PA  PP P P+ A L  ++  G+   PAGP 
Sbjct: 246 AAAPPAPAAPS---------PPAAPAPAAPAAAPPPPPPAPATL--ARPPGH---PAGP- 290

Query: 616 AGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSP 675
                   PT   A+P   A   G       +  A P P P    P     Q  P     
Sbjct: 291 --------PTAAPAVPPPAAAQNG------GSAGAAPAPAPAAGGPAGVSGQPGP----- 331

Query: 676 SGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIFE 735
            G A +    G+++ SP+           +L  S  A   +S  I   +Q    S     
Sbjct: 332 -GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVP 390

Query: 736 PGADG 740
           P A G
Sbjct: 391 PPAPG 395



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 90/304 (29%), Positives = 109/304 (35%), Gaps = 49/304 (16%)

Query: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS 444
           G   PP P A +PP  P  A+  A       + A  A PPG    P T+ P V       
Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV------- 297

Query: 445 VEPVVMMHMNIQDSGTQPGGVPSA--PTGPLGPPGHGQTLGQQVPGFPT-APTRVVIARP 501
             P      N   +G  P   P+A  P G  G PG G       PG    +P RVV A  
Sbjct: 298 --PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA-- 353

Query: 502 TPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQ-LLMQPVLV---AQGTPGMA 557
                       PP + TL  +G  + A  A MV G   Q  L  P  V   A GTP   
Sbjct: 354 -----------APPAAQTLAASGPASTA--ASMVIGPTMQGALPSPAAVPPPAPGTPTGL 400

Query: 558 PPPAPATASASAGTTNTATTAG------PAPGGPAQPPPTPQPSMADLQFSQLLGNLLGP 611
           P  A    + S   T TATT+G      P    P  P P   P+  ++Q  QL      P
Sbjct: 401 PKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPT--NIQNFQL------P 452

Query: 612 AGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPP 671
            G       V S    + M    A  Q         QT   P P  P   P  +  T+  
Sbjct: 453 PGMVL----VRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQA 508

Query: 672 PGSP 675
           PG+P
Sbjct: 509 PGTP 512



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 55/186 (29%), Positives = 66/186 (35%), Gaps = 44/186 (23%)

Query: 533 QMVSGLVGQLLMQPVLVAQGTPGMAP--PPAPATASASAG----TTNTATTAGPAPGGPA 586
           ++VS LVG L  Q    A     +AP  P   A A+ + G    + + A  AG  P  PA
Sbjct: 20  KVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPA 79

Query: 587 Q--PPPTPQPSMADLQFSQLLGNLLGPAGPGAGG---SGVASP--TITVAMPGVPAFLQG 639
           +  P   P+P  A            G A PG GG    G  SP   +  A P  PA    
Sbjct: 80  EGAPGAAPEPPPA------------GRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLR 127

Query: 640 MTDFLQATQTAPPP--------PPPPPPPPPAP------EQQTMPPPG-----SPSGGAG 680
                 A   AP P        P P P  P  P        +  P PG      P  G G
Sbjct: 128 PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPG 187

Query: 681 SPGGLG 686
            P G G
Sbjct: 188 KPAGPG 193



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 121/524 (23%), Positives = 173/524 (33%), Gaps = 123/524 (23%)

Query: 86  ERAPPQTHLPSGASSGTGSASATHGGGSPPGT-------RGPGASVHDRNA-----NSYV 133
           E AP     P+G ++    A    G G  PG         GPGA+     +     + + 
Sbjct: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA 210

Query: 134 MVGTFNLPSDGSAVDVHINMEQAP---IQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQ 190
                +L ++G A  + +    AP   IQ+ P V                        P 
Sbjct: 211 AAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP--------------APAAPS 256

Query: 191 PQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGPAP 250
           P  +  P  P A  P P    +  + P    A P  P  A  V   A AQN     G A 
Sbjct: 257 PPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP--PTAAPAVPPPAAAQNG----GSAG 310

Query: 251 AGPTPAPETNAP----NHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYNNN 306
           A P PAP    P      P P                            GAAA       
Sbjct: 311 AAPAPAPAAGGPAGVSGQPGP----------------------------GAAAAAPAPG- 341

Query: 307 HEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHL---HVVRPMSHYTTPMV 363
               E  +R++     + + L  +  A +     +  T    L     V P +  T   +
Sbjct: 342 -VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL 400

Query: 364 LQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPP-PGPGQASSVAPSSTNVESSAEGAP 422
            + AA  +  ++  T T T +G R   TP   AP  P P Q      + TN+++      
Sbjct: 401 PKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQ------NPTNIQNF---QL 451

Query: 423 PPGPAPPPATSHPRVIRISHQSVEPV-VMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQT 481
           PPG      + + +++ I  Q++  +    H   Q   T     P+ PT    PP    T
Sbjct: 452 PPGMV-LVRSENGQLLMIPQQALAQMQAQAHAQPQ---TTMAPRPATPTS--APPVQIST 505

Query: 482 LGQQVPGFP-----TAPTRVV----IARPT--PPQARPSHPGGPP---VSGTLQGAGLGT 527
           +  Q PG P       PT ++     A+ T  P       PG  P   + G  Q A LGT
Sbjct: 506 V--QAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGT 563

Query: 528 NASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGT 571
             +                  V  GTP    P A  T+SA+  T
Sbjct: 564 ATA------------------VQTGTPQRTVPGATTTSSAATET 589



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 37/146 (25%), Positives = 50/146 (34%), Gaps = 24/146 (16%)

Query: 924  PVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAE-------- 975
            P  P  +++    VG    P P  P        A+P        PAP T A         
Sbjct: 231  PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290

Query: 976  -EAMSRGPPP--APEGGSRDEQD----------GASAETEPWAAAVPPEWVPIIQQDIQS 1022
              A    PPP  A  GGS               G S +  P AAA  P   P ++ +   
Sbjct: 291  PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP--APGVKAE-SP 347

Query: 1023 QRKVKPQPPLSDAYLSGMPAKRRKTM 1048
            +R V+  PP +    +  PA    +M
Sbjct: 348  KRVVQAAPPAAQTLAASGPASTAASM 373



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 940 PPQPLPEEPMEVQG----AERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQD 995
           P  P P  P+   G    A +  P P+    S AP   A  A++ GP PAP G ++    
Sbjct: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP-VPAAAAVAAGPEPAPAGPAKPAGP 163

Query: 996 GASA 999
            A A
Sbjct: 164 AALA 167


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 88/309 (28%), Positives = 95/309 (30%), Gaps = 75/309 (24%)

Query: 388 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPG----PAPPPATSHPRVIRISHQ 443
           PPP    E  PP  G  S   P         EG PP G      PPP    P       +
Sbjct: 51  PPPPGKPEGRPPQGGNQSQGPPPRPG---KPEGPPPQGGNQSQGPPPRPGKP-------E 100

Query: 444 SVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVP---GFPTAPTRVVIAR 500
              P           G Q  G P  P  P GPP  G    Q  P   G P  P      +
Sbjct: 101 GQPP---------QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQ 151

Query: 501 PTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPP 560
              P  RP  P GPP  G  Q  G   +    +   G   Q          G     PPP
Sbjct: 152 SQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPE---GPPPQ---------GGNQSQGPPP 199

Query: 561 APATASASAGTTNTATTAGPAPGGPAQ---PPPTPQPSMADLQFSQLLGNLLGPAGPGAG 617
            P                GP P G  Q   PPP P             G   GP  P  G
Sbjct: 200 RPGKPE------------GPPPQGGNQSQGPPPRP-------------GKPEGP--PSQG 232

Query: 618 GSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPP--APEQQTMPPPGSP 675
           G+    P      P  P   +G        Q  PPP  P  PPPP   P+Q   PP G P
Sbjct: 233 GNKPQGPPPHPGKPQGPPPQEG-----NKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKP 287

Query: 676 SGGAGSPGG 684
            G    P G
Sbjct: 288 QGPPPPPQG 296



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 60/219 (27%), Positives = 69/219 (31%), Gaps = 49/219 (22%)

Query: 383 GNGTRPPPT--PNAEAPPPGPGQASSVAPSSTNVESSAEGAPP-PG--PAPPPATSHPRV 437
           G    PPP     ++ PPP PG+     P   N    ++G PP PG    PPP       
Sbjct: 118 GKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGN---QSQGPPPRPGKPEGPPP------- 167

Query: 438 IRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQ---QVPGFPTAPT 494
                                G Q  G P  P  P GPP  G    Q     PG P  P 
Sbjct: 168 -------------------QGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 208

Query: 495 RVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP 554
                +   P  RP  P GPP  G  +  G   +    Q      G    +P     G P
Sbjct: 209 PQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRP--PPPGRP 266

Query: 555 GMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQ 593
              PPP            N      P  G P  PPP PQ
Sbjct: 267 QGPPPPG----------GNPQQPLPPPAGKPQGPPPPPQ 295



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 79/313 (25%), Positives = 86/313 (27%), Gaps = 125/313 (39%)

Query: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPP-PGP--APPPATSHPRVIRIS 441
           G RP      +  PP PG+     P   N    ++G PP PG    PPP           
Sbjct: 38  GRRPQGGNQPQRTPPPPGKPEGRPPQGGN---QSQGPPPRPGKPEGPPP----------- 83

Query: 442 HQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARP 501
                            G Q  G P  P  P G P  G   G Q  G             
Sbjct: 84  ---------------QGGNQSQGPPPRPGKPEGQPPQG---GNQSQG------------- 112

Query: 502 TPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPA 561
             P  RP  P GPP  G  Q  G                                 PPP 
Sbjct: 113 --PPPRPGKPEGPPPQGGNQSQG---------------------------------PPPR 137

Query: 562 PATASASAGTTNTATTAGPAPGGPAQ---PPPTPQPSMADLQFSQLLGNLLGPAGPGAGG 618
           P                GP P G  Q   PPP P             G   GP  P  GG
Sbjct: 138 PGKPE------------GPPPQGGNQSQGPPPRP-------------GKPEGP--PPQGG 170

Query: 619 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPP------ 672
           +    P      P  P    G       +Q  PP P  P  PPP    Q+  PP      
Sbjct: 171 NQSQGPPPHPGKPEGPPPQGG-----NQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 225

Query: 673 -GSPSGGAGSPGG 684
            G PS G   P G
Sbjct: 226 EGPPSQGGNKPQG 238



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 64/237 (27%), Positives = 69/237 (29%), Gaps = 65/237 (27%)

Query: 459 GTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSG 518
           G QP   P  P  P G P  G    Q  P  P  P         PPQ      G PP  G
Sbjct: 44  GNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKP------EGPPPQGGNQSQGPPPRPG 97

Query: 519 TLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTA 578
             +G                      QP     G     PPP P                
Sbjct: 98  KPEG----------------------QPP--QGGNQSQGPPPRPGKPE------------ 121

Query: 579 GPAPGGPAQ---PPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPA 635
           GP P G  Q   PPP P             G   GP  P  GG+    P      P  P 
Sbjct: 122 GPPPQGGNQSQGPPPRP-------------GKPEGP--PPQGGNQSQGPPPRPGKPEGPP 166

Query: 636 FLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSP 692
              G       +Q  PP P  P  PPP    Q+  PP  P    G P   G +S  P
Sbjct: 167 PQGG-----NQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 218



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 29/105 (27%), Positives = 36/105 (34%), Gaps = 23/105 (21%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEP-------------VESEAPPREPMEAEE 232
           +GG QPQ + PPP  P   P      SQ   P              +S+ PP  P + E 
Sbjct: 42  QGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG 101

Query: 233 V------EERAPAQNPELTPGPAPAGPT----PAPETNAPNHPSP 267
                  + + P   P    GP P G      P P    P  P P
Sbjct: 102 QPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPP 146



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 26/83 (31%), Positives = 31/83 (37%), Gaps = 14/83 (16%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL- 244
           +GG +PQ   P P  P   P           P E   P R P          P  NP+  
Sbjct: 231 QGGNKPQGPPPHPGKPQGPP-----------PQEGNKPQRPPPPGRPQGPPPPGGNPQQP 279

Query: 245 TPGPA--PAGPTPAPETNAPNHP 265
            P PA  P GP P P+   P+ P
Sbjct: 280 LPPPAGKPQGPPPPPQGGRPHRP 302



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 24/88 (27%), Positives = 30/88 (34%), Gaps = 8/88 (9%)

Query: 188 GPQPQHSQ----PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPE 243
           GP PQ       PPP+P     +P    +Q+  P      P  P      + + P   P 
Sbjct: 80  GPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG 139

Query: 244 LTPGPAPAGPT----PAPETNAPNHPSP 267
              GP P G      P P    P  P P
Sbjct: 140 KPEGPPPQGGNQSQGPPPRPGKPEGPPP 167



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 24/88 (27%), Positives = 30/88 (34%), Gaps = 8/88 (9%)

Query: 188 GPQPQHSQ----PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPE 243
           GP PQ       PPP+P      P    +Q+  P      P  P      + + P  +P 
Sbjct: 122 GPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPG 181

Query: 244 LTPGPAPAGPT----PAPETNAPNHPSP 267
              GP P G      P P    P  P P
Sbjct: 182 KPEGPPPQGGNQSQGPPPRPGKPEGPPP 209



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 8/60 (13%)

Query: 938 GDPPQP-LPEEPMEVQGAE-RASPEPQRENASPAPGTTAEEAMS------RGPPPAPEGG 989
           G PP P  P+ P   +G + +  P P R    P PG   ++ +       +GPPP P+GG
Sbjct: 238 GPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGG 297



 Score = 34.3 bits (77), Expect = 0.68
 Identities = 24/86 (27%), Positives = 30/86 (34%), Gaps = 6/86 (6%)

Query: 186 RGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELT 245
           +GG Q Q   PPP+P      P    +Q+  P      P  P      + + P   P   
Sbjct: 105 QGGNQSQG--PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 162

Query: 246 PGPAPAGPT----PAPETNAPNHPSP 267
            GP P G      P P    P  P P
Sbjct: 163 EGPPPQGGNQSQGPPPHPGKPEGPPP 188



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 27/99 (27%), Positives = 31/99 (31%), Gaps = 19/99 (19%)

Query: 188 GPQPQHSQ----PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPE 243
           GP PQ       PPP P      P    +Q+  P      P  P      + + P   P 
Sbjct: 164 GPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPG 223

Query: 244 LTPGP------APAGPTPAP---------ETNAPNHPSP 267
              GP       P GP P P         E N P  P P
Sbjct: 224 KPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPP 262



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 35/122 (28%), Positives = 42/122 (34%), Gaps = 7/122 (5%)

Query: 938  GDPPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGA 997
            G PP+P   E    QG  ++   P R      P        S+GPPP P         G 
Sbjct: 91   GPPPRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGN-QSQGPPPRPGKPEGPPPQGG 149

Query: 998  SAETEPWAAAVPPEWVPIIQQDIQSQ----RKVKPQ-PPLSDAYLSGMPAKRRKTMQGEG 1052
            +    P      PE  P  Q   QSQ       KP+ PP      S  P  R    +G  
Sbjct: 150  NQSQGPPPRPGKPEGPP-PQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPP 208

Query: 1053 PQ 1054
            PQ
Sbjct: 209  PQ 210



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 23/86 (26%), Positives = 28/86 (32%), Gaps = 8/86 (9%)

Query: 188 GPQPQHSQ----PPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPE 243
           GP PQ       PPP+P      P    +Q+  P      P  P      + + P   P 
Sbjct: 143 GPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPG 202

Query: 244 LTPGPAPAGPT----PAPETNAPNHP 265
              GP P G      P P    P  P
Sbjct: 203 KPEGPPPQGGNQSQGPPPRPGKPEGP 228



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 35/120 (29%), Positives = 41/120 (34%), Gaps = 7/120 (5%)

Query: 940  PPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASA 999
            PP P   E    QG  ++   P R      P        S+GPPP P         G + 
Sbjct: 51   PPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGN-QSQGPPPRPGKPEGQPPQGGNQ 109

Query: 1000 ETEPWAAAVPPEWVPIIQQDIQSQ----RKVKPQ-PPLSDAYLSGMPAKRRKTMQGEGPQ 1054
               P      PE  P  Q   QSQ    R  KP+ PP      S  P  R    +G  PQ
Sbjct: 110  SQGPPPRPGKPEGPP-PQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQ 168



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 14/97 (14%)

Query: 938  GDPPQPLPEEPMEVQGAERAS---PEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQ 994
            G PP+P   E    QG  ++    P P +    P  G       S+GPPP P        
Sbjct: 154  GPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGN----QSQGPPPRPGKPEGPPP 209

Query: 995  DGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPP 1031
             G +    P      PE  P       SQ   KPQ P
Sbjct: 210  QGGNQSQGPPPRPGKPEGPP-------SQGGNKPQGP 239



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 29/104 (27%), Positives = 33/104 (31%), Gaps = 8/104 (7%)

Query: 938  GDPPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGA 997
            G PP P   E    QG  ++   P R      P        S+GPPP P         G 
Sbjct: 175  GPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGN-QSQGPPPRPGKPEGPPSQGG 233

Query: 998  SAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMP 1041
            +    P     PP   P   Q    Q   KPQ P       G P
Sbjct: 234  NKPQGP-----PPH--PGKPQGPPPQEGNKPQRPPPPGRPQGPP 270


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 89/302 (29%), Positives = 105/302 (34%), Gaps = 44/302 (14%)

Query: 388  PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
            PPP P A  PPP P   + + P          G PPP P P  A   P  +  +   + P
Sbjct: 912  PPPLPGAGIPPPPPLPGAGILPLPP---LPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968

Query: 448  VVMMHMNIQDSGTQPG-GVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQA 506
              +    I      PG G+P  P  PL  PG G      +PG    P   +     PP  
Sbjct: 969  P-LPGAGIPPPPPLPGAGIPPPP--PL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPP- 1022

Query: 507  RPSHPG-GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATA 565
             P  PG G P    L GAG+     L          +   P L   G P   PPP P   
Sbjct: 1023 -PPLPGAGIPPPPPLPGAGIPPPPPLPG------AGIPPPPPLPGAGIP--PPPPLPGAG 1073

Query: 566  SASAGTTNTATTAGPAP-GGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASP 624
                     A    P P  G   PPP P P +       L G  + P  P   G+G+  P
Sbjct: 1074 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPP-LPGAGIPPP 1132

Query: 625  TITVAMPGVPAFLQGMTDFLQATQTAPPPPPPP----PPPPPAPEQQTMPPPGSPSGGAG 680
                 +PG                  PPPPP P    PPPPP P     PPP  P  G  
Sbjct: 1133 P---PLPGAGI---------------PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP 1174

Query: 681  SP 682
             P
Sbjct: 1175 PP 1176



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 94/325 (28%), Positives = 112/325 (34%), Gaps = 52/325 (16%)

Query: 380  TMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVE----SSAEGAPPPGPAPPPATSHP 435
            +M G G  PPP      PPP PG      PS+   +       E  PPP P P P    P
Sbjct: 869  SMPGLGMVPPP------PPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPP-PPPLPGAGIP 921

Query: 436  RVIRISHQSVEPVVMMHMNIQDSGTQPGG-VPSAPTGPLGP-PGHGQTLGQQVPGFPTAP 493
                +    + P+  +      +G  P   +P A   P  P PG G  L   +PG    P
Sbjct: 922  PPPPLPGAGILPLPPL----PGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPP 977

Query: 494  TRVVIARPTPPQARPSHPG-GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQG 552
               +     PP   P  PG G P    L GAG+     L          +   P L   G
Sbjct: 978  PPPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPG------AGIPPPPPLPGAG 1029

Query: 553  TPGMAPPPAPATASASAGTTNTATTAGPAP-GGPAQPPPTPQPSMADLQFSQLLGNLLGP 611
             P   PPP P            A    P P  G   PPP P P         L G  + P
Sbjct: 1030 IP--PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087

Query: 612  AGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPP----PPPPPAPEQQ 667
              P   G+G+  P     +PGV                 PPPPP P    PPPPP P   
Sbjct: 1088 PPP-LPGAGIPPPP---PLPGVGI---------------PPPPPLPGAGIPPPPPLPGAG 1128

Query: 668  TMPPPGSPSGGAGSPGGLGLESLSP 692
              PPP  P  G   P  L    + P
Sbjct: 1129 IPPPPPLPGAGIPPPPPLPRVGIPP 1153



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 88/298 (29%), Positives = 101/298 (33%), Gaps = 55/298 (18%)

Query: 388  PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
            PPP P A  PPP P   + + P          GA  P P P P    P           P
Sbjct: 967  PPPLPGAGIPPPPPLPGAGIPPPPP-----LPGAGIPPPPPLPGAGIP----------PP 1011

Query: 448  VVMMHMNIQDSGTQPG-GVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQA 506
              +    I      PG G+P  P  PL  PG G      +PG    P   +     PP  
Sbjct: 1012 PPLPGAGIPPPPPLPGAGIPPPP--PL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPP- 1066

Query: 507  RPSHPG-GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATA 565
             P  PG G P    L GAG+     L          +   P L   G P   PPP P   
Sbjct: 1067 -PPLPGAGIPPPPPLPGAGIPPPPPLPG------AGIPPPPPLPGVGIP--PPPPLPGAG 1117

Query: 566  SASAGTTNTATTAGPAP-GGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASP 624
                     A    P P  G   PPP P P +       L G  + P  P   G+G+  P
Sbjct: 1118 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP-LPGAGIPPP 1176

Query: 625  TITVAMPGVPAFLQGMTDFLQATQTAPPPPPPP----PPPPPAPEQQTMPPPGSPSGG 678
                 +PGV                 PPPPP P    PPPPP P     PPP  P  G
Sbjct: 1177 P---PLPGVGI---------------PPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 83/304 (27%), Positives = 99/304 (32%), Gaps = 38/304 (12%)

Query: 388  PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
            PPP P A  PPP P   + + P          G PPP P P      P  +        P
Sbjct: 978  PPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPP 1033

Query: 448  VVMMHMNIQDSGTQPG-GVPSAPTGP-LGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQ 505
              +    I      PG G+P  P  P  G P      G  +P  P  P   +   P PP 
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI--PPPPPL 1091

Query: 506  ARPSHPGGPPVSGT-------LQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAP 558
                 P  PP+ G        L GAG+     L          +   P L   G P   P
Sbjct: 1092 PGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG------AGIPPPPPLPGAGIP--PP 1143

Query: 559  PPAPATASASAGTTNTATTAGPAP-GGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAG 617
            PP P            A    P P  G   PPP P P +       L G  + P  P   
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP-LP 1202

Query: 618  GSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSG 677
            G+G+  P     M   PA              APP PPP    PP P      PP  P  
Sbjct: 1203 GAGIPPPPPLPGMGIPPA-------------PAPPLPPPGTGIPPPPLLPVSGPPLLPQV 1249

Query: 678  GAGS 681
            G+ +
Sbjct: 1250 GSST 1253



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 70/243 (28%), Positives = 84/243 (34%), Gaps = 19/243 (7%)

Query: 388  PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
            PPP P A  PPP P   + + P          G PPP P P      P  +        P
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPP---LPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPP 1099

Query: 448  VVMMHMNIQDSGTQPG-GVPSAPTGP-LGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQ 505
              +  + I      PG G+P  P  P  G P      G  +P  P  P RV I  P PP 
Sbjct: 1100 PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-RVGIP-PPPPL 1157

Query: 506  ARPSHPGGPPVSGT-------LQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAP 558
                 P  PP+ G        L G G+     L  +       L    +      PGM  
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGI 1217

Query: 559  PPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGG 618
            PPAPA      GT        P  G    PP  PQ   + L   Q+ G L  P   G  G
Sbjct: 1218 PPAPAPPLPPPGTGIPPPPLLPVSG----PPLLPQVGSSTLPTPQVCGFLPPPLPSGLFG 1273

Query: 619  SGV 621
             G+
Sbjct: 1274 LGM 1276



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 69/262 (26%), Positives = 91/262 (34%), Gaps = 72/262 (27%)

Query: 454 NIQDSGTQPGGV---------PSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIA----R 500
           +IQ S T+ GGV         P  P  P G     QT          +P R+ +     +
Sbjct: 743 SIQTSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQ 802

Query: 501 PTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGM---A 557
           PT   ++P     PP    L  AG G   S          Q   +  + +         +
Sbjct: 803 PTQSISQP-----PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPS 857

Query: 558 PPPAPATASASAGTTNTATTAGPAPG-GPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGA 616
           PPP P T S+S+            PG G   PPP P P                      
Sbjct: 858 PPPLPCTESSSS-----------MPGLGMVPPPPPPLP---------------------- 884

Query: 617 GGSGVASPTI-TVAMPGVPAFLQGMTDFLQATQTAPPPPPP-----PPPPPPAPEQQTMP 670
              G+  PT+ + A+P  P         LQ T+  PPPPPP      PPPPP P    +P
Sbjct: 885 ---GMTVPTLPSTAIPQPPP--------LQGTEMLPPPPPPLPGAGIPPPPPLPGAGILP 933

Query: 671 PPGSPSGGAGSPGGLGLESLSP 692
            P  P  G   P  L   ++ P
Sbjct: 934 LPPLPGAGIPPPPPLPGAAIPP 955



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 46/146 (31%), Positives = 51/146 (34%), Gaps = 23/146 (15%)

Query: 381  MTGNGT-RPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP----PPATSHP 435
            + G G   PPP P    PPP P   + + P          G PPP P P    PP    P
Sbjct: 1135 LPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP---PLPGAGIPPPPPLPGVGIPPPPPLP 1191

Query: 436  RVIRISHQSVEPVVMMHMNIQDSGTQPG-GVPSAPTGPLGPPGHGQTLGQQVPGFPTAPT 494
             V         P  +    I      PG G+P AP  PL PPG          G P  P 
Sbjct: 1192 GV-----GIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG---------TGIPPPPL 1237

Query: 495  RVVIARPTPPQARPSHPGGPPVSGTL 520
              V   P  PQ   S    P V G L
Sbjct: 1238 LPVSGPPLLPQVGSSTLPTPQVCGFL 1263



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 6/74 (8%)

Query: 196  PPPQPPAVTPEPVALSSQTSEPVES----EAPPREPMEAEEVEERAPAQNPELTPGPAPA 251
            PPP P A  P P  L      P         PP  P+    +    P     + P PAP 
Sbjct: 1165 PPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP- 1223

Query: 252  GPTPAPETNAPNHP 265
             P P P T  P  P
Sbjct: 1224 -PLPPPGTGIPPPP 1236



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 15/100 (15%)

Query: 585 PAQPPP--TPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTD 642
           PA PP   +PQP      F  L   LLGP+G    G+G A  +     P     L  ++D
Sbjct: 232 PAAPPTAVSPQPGA----FLGLDRFLLGPSG----GAGEAPGS-----PDTEQALSALSD 278

Query: 643 FLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSP 682
             ++    P  P  PP P   P  +    P +      SP
Sbjct: 279 LPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSP 318



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 44/176 (25%), Positives = 64/176 (36%), Gaps = 28/176 (15%)

Query: 937  VGDPPQPLPEEPMEVQGAERASPEPQRENAS-PAPGTTAEEAMSRGPPPAPEGGSRDEQD 995
            + D P+ L  EP E Q        P  E  S PA    A+++ S    P PE G  +E  
Sbjct: 276  LSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAA 335

Query: 996  GA--------SAETEPWAAAVPP------EWVPIIQQDIQSQRKVKPQPPL------SDA 1035
            GA          E E  A    P      EW P + +D   +   +P+         + A
Sbjct: 336  GAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAA 395

Query: 1036 YLSGMPAKRRKTMQGEGPQLLLS----EAVSRAAKAAGARPLTSPESLSRDLEAPE 1087
             L G PA  ++  +   P  L++    +  +R   +    P  SP    R    PE
Sbjct: 396  SLPGSPAPSQRCFK---PYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPE 448



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 28/99 (28%), Positives = 35/99 (35%), Gaps = 14/99 (14%)

Query: 611 PAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMP 670
           P  PGA           +++   P  +    D  Q TQ+   PPPPP             
Sbjct: 768 PCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSL----------- 816

Query: 671 PPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGS 709
                S G G PG     S+S EF TS    V S+   S
Sbjct: 817 ---LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNS 852


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 74.7 bits (182), Expect = 5e-13
 Identities = 89/356 (25%), Positives = 125/356 (35%), Gaps = 55/356 (15%)

Query: 400 GPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSG 459
           GPG    +A ++T       G    G  PP     P       + + P    H+ ++   
Sbjct: 502 GPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMK--- 558

Query: 460 TQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGT 519
                      G  GP G     G+++PG              PP+  PS P GP     
Sbjct: 559 -----------GQAGPKGEKGDAGEELPG--------------PPE--PSGPVGPTAGAE 591

Query: 520 LQGAGLGTNASLAQMVSGLVG--QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATT 577
            +G+GLG  + +      LVG  QLL       +G PG   PP P       G   T   
Sbjct: 592 AEGSGLGWGSDVGSGSGDLVGSEQLL-------RGPPG---PPGPPGLPGIPGKPGTDVF 641

Query: 578 AGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFL 637
            GP PG P +  P  +P     +    +    G  G   G  G   P  +V   G P   
Sbjct: 642 MGP-PGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGM-KGEKGARGPNGSVGEKGDPG-N 698

Query: 638 QGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTS 697
           +G+         A PP    PP PP        PPG P  G G   GLG E       T 
Sbjct: 699 RGLPGPPGKKGQAGPPGVMGPPGPPG-------PPGPP--GPGCTMGLGFEDTEGSGSTQ 749

Query: 698 VV-QGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLL 752
           ++ +  LS    ++G +    +      + + G+S +  PG  G  G    L + L
Sbjct: 750 LLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSL 805



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 81/323 (25%), Positives = 111/323 (34%), Gaps = 52/323 (16%)

Query: 394 AEAP--PPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMM 451
           AE P    G  +ASSV      +  S E  P  G  P P  +  R+   +    E +  M
Sbjct: 365 AEVPISTAGEAEASSVPTGGPTLSMSTEN-PEEGVTPGP-DNEERLAATAAGEAEALASM 422

Query: 452 HMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHP 511
              ++ SG  PG +  + +         Q+LG++    P++   +  A      +  +  
Sbjct: 423 PGEVEASGVAPGELDLSMS--------AQSLGEEATVGPSSEDSLTTAAAATEVSLSTFE 474

Query: 512 GGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGT 571
                    + +G+ T+  LA + +       M P       PG     A AT      T
Sbjct: 475 DE-------EASGVPTD-GLAPLTA------TMAPERAVTSGPGDEEDLAAATTEEPLIT 520

Query: 572 TNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGP----GAGG--------- 618
                +  P P GP  P PT  P        +    + G AGP    G  G         
Sbjct: 521 AGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEP 580

Query: 619 SGVASPTITVAMPGV-----PAFLQGMTDFLQATQTAPPPPPPPPPP-----PPAPEQQT 668
           SG   PT      G           G  D + + Q    PP PP PP     P  P    
Sbjct: 581 SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDV 640

Query: 669 -MPPPGSP--SGGAGSPGGLGLE 688
            M PPGSP   G AG PG  G E
Sbjct: 641 FMGPPGSPGEDGPAGEPGPPGPE 663



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 71/272 (26%), Positives = 88/272 (32%), Gaps = 65/272 (23%)

Query: 461  QPG--GVPSAPTGPLGPPGHGQTLGQQVPGFPTAP----------TRVVIARPTPPQARP 508
            +PG  G P  P GP GPPGH    G  +PG P  P             VI +  P    P
Sbjct: 883  EPGMHGAPG-PMGPKGPPGHKGEFG--LPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGP 939

Query: 509  SHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQP---VLVAQGTPGMAPPPAPATA 565
              P GPP      GA +         + G +  + ++P   + V    PG          
Sbjct: 940  PGPPGPP------GAVIN--------IKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGV 985

Query: 566  SASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLG--------------- 610
                G+     + G      AQ PP P   +A L+    L NL G               
Sbjct: 986  KGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLR--HFLNNLKGENGDKGFKGEKGEKG 1043

Query: 611  --------------PAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPP- 655
                          P  PG  G    +       PG P  L G   F +     PP PP 
Sbjct: 1044 DINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPG-LPGPPGFGRPGDPGPPGPPG 1102

Query: 656  PPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGL 687
            PP PP        +P P  P G  G PG   L
Sbjct: 1103 PPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 80/323 (24%), Positives = 95/323 (29%), Gaps = 61/323 (18%)

Query: 388 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAP-PPGPAPPP----ATSHPRVIRISH 442
           PP  P     P  PG    + P  +  E    G P PPGP   P    AT  P +     
Sbjct: 623 PPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGM----- 677

Query: 443 QSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPT 502
                           G +    P+   G  G PG+         G P  P +   A P 
Sbjct: 678 ---------------KGEKGARGPNGSVGEKGDPGN--------RGLPGPPGKKGQAGPP 714

Query: 503 PPQARPSHPG--GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVL----VAQGTPGM 556
                P  PG  GPP  G   G G                QLL +P L     A G  G 
Sbjct: 715 GVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGST------QLLNEPKLSRPTAAIGLKGE 768

Query: 557 APPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMAD-----LQFSQLLGNLLGP 611
                P       G    +    P P GP         S+ +     + FS  +  L+GP
Sbjct: 769 KGDRGP---KGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSD-IPELVGP 824

Query: 612 AGPGA-----GGSGVASPTITVAMPGVPAFL--QGMTDFLQATQTAPPPPPPPPPPPPAP 664
            GP       G  G   P     +PG P     QG      A  T   P          P
Sbjct: 825 PGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEP 884

Query: 665 EQQTMPPPGSPSGGAGSPGGLGL 687
                P P  P G  G  G  GL
Sbjct: 885 GMHGAPGPMGPKGPPGHKGEFGL 907



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 82/343 (23%), Positives = 108/343 (31%), Gaps = 42/343 (12%)

Query: 385  GTRPPPTPNAEAPPPG-PGQASSVAPSSTNVESSAEGAPPPG-PAPPPATSHPRVIRISH 442
            G + PP    E   PG PG+        T  +       PPG P PP     P  +    
Sbjct: 894  GPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIK 953

Query: 443  QSVEPV-VMMHMNIQDSGTQPGGVP-------SAPTGPLGPPGH-GQTLGQQVPGFPTAP 493
             ++ P+ V  H  +      PG              G  G PG  G+   Q   G P  P
Sbjct: 954  GAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPP 1013

Query: 494  TRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGT 553
              +   R      +  + G     G     G    + L     GL G     P    Q  
Sbjct: 1014 LDLAYLRHFLNNLKGEN-GDKGFKGEKGEKGDINGSFLMSGPPGLPGN----PGPAGQKG 1068

Query: 554  PGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAG 613
              +  P  P  A    G         P P GP  PP  P    A L  +  L    GP G
Sbjct: 1069 ETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPP----AILGAAVALPGPPGPPG 1124

Query: 614  -PGAGGSGVASPTIT----------VAMPGVPAFLQGMTDF----------LQATQTAP- 651
             PG  GS       +          + + G   +L+  T+F          LQ  +  P 
Sbjct: 1125 QPGLPGSRNLVTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPI 1184

Query: 652  PPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEF 694
            P   PPPP   +   Q +PPP   S        L L +L+  F
Sbjct: 1185 PADSPPPPALSSNPHQLLPPPNPISSANYEKPALHLAALNMPF 1227


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 112/440 (25%), Positives = 142/440 (32%), Gaps = 120/440 (27%)

Query: 381  MTGNGTRPPPTPNAEAPPPG------------------PGQASSVAPSSTNVESSAEGAP 422
            M   G   P  P  EA PPG                  PG   SV P  ++     +G P
Sbjct: 620  MGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPP 679

Query: 423  -------------------------PPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQD 457
                                     PPGP        PR +     + EP +     +  
Sbjct: 680  GPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGL-----TGEPGMR---GLPG 731

Query: 458  SGTQPGGVPSAPTGPLGPPGHGQTLGQQ----------VPGFPTAPTRVVIARPTPPQAR 507
            +  +PG       GP GP GH    G+Q           PG    P +  +  P  PQ  
Sbjct: 732  AVGEPGA--KGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGL 789

Query: 508  PSHPGGPPVSGTLQGAG--LGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATA 565
            P  PG P + G     G  + +  S    V G  G         A G PG    P PA  
Sbjct: 790  PGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPP------GAMGPPGPPGAPGPAGP 843

Query: 566  SASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGP-GAGGSGVASP 624
            +   G        GP   GP  P   P PS+             GP GP G  G G+  P
Sbjct: 844  AGLPGHQEVLNLQGPP--GPPGPRGPPGPSIP------------GPPGPRGPPGEGLPGP 889

Query: 625  TITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGG 684
                  PG P        FL  ++T    PP PP PP     Q   PPG P G  G  G 
Sbjct: 890  ------PGPPG------SFLSNSETFLSGPPGPPGPPGPKGDQ--GPPG-PRGHQGEQGL 934

Query: 685  LGLESLSPEFFTSVVQGVLS--------------SLLGSLGARAGSSESIAAFIQRLSGS 730
             G  +     F   +QG                  + G+LG  +G SE  ++    +SG 
Sbjct: 935  PGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSG- 993

Query: 731  SNIFEPGADGALGFFGALLS 750
                 PG  G  G  G++ S
Sbjct: 994  ----PPGPPGPPGPPGSISS 1009



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 106/437 (24%), Positives = 156/437 (35%), Gaps = 96/437 (21%)

Query: 385  GTRPPPTPNAEAPPPGPG--QASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISH 442
            G   PP P  +  PPGP   Q     P  +   SS+ G    GP  PP    P+      
Sbjct: 909  GPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPK-----G 963

Query: 443  QSVEPVVMMHMNIQDSGTQPGGV--------PSAPTGPLGPPGHGQTLGQQVPGFPTAPT 494
               +P V   + I  SG   GG         P  P GP GPPG   + GQ++  + +   
Sbjct: 964  DKGDPGVPGALGIP-SGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYM 1022

Query: 495  RVVIARP--TPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGL-------------- 538
            +    R   +  Q  P  PG P    T+ G     +   + +VS L              
Sbjct: 1023 QSDSIRSYLSGVQGPPGPPGPPGPVTTITGETFDYSELASHVVSYLRTSGYGVSLFSSSI 1082

Query: 539  -------------VGQLLMQPVLVAQGTPGMAPPPAPAT--------ASASAGTTNTATT 577
                         V Q L Q ++  +G PG  PP A           A  S+   +  ++
Sbjct: 1083 SSEDILAVLQRDDVRQYLRQYLMGPRGPPG--PPGASGDGSLLSLDYAELSSRILSYMSS 1140

Query: 578  AGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPA-- 635
            +G + G P  P P   P +    + +LL  L      G+   G+  P      PG+P   
Sbjct: 1141 SGISIGLPGPPGP---PGLPGTSYEELLSLL-----RGSEFRGIVGPPGPPGPPGIPGNV 1192

Query: 636  ----FLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLS 691
                 ++ ++ +L     +  P PP PP PP P      PPG  SG   +      +S  
Sbjct: 1193 WSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPR----GPPG-VSGALATYAAENSDSFR 1247

Query: 692  PEFFTSVVQ-GVLSSLLGSLG--------------------ARAGSSESIAAFIQRLSGS 730
             E  + +    V S ++G  G                    +R  SS S ++ ++R S  
Sbjct: 1248 SELISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSY 1307

Query: 731  SNIFEPGADGALGFFGA 747
            S+    G  GA G  GA
Sbjct: 1308 SSSMSTGGGGA-GSLGA 1323



 Score = 34.7 bits (78), Expect = 0.52
 Identities = 50/208 (24%), Positives = 64/208 (30%), Gaps = 31/208 (14%)

Query: 504 PQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPA 563
           P+     PG P + G L   G        +   G VG   M+  +  +G  G   P   A
Sbjct: 580 PKGDRGFPGTPGIPGPLGHPG----PQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEA 635

Query: 564 TASASAGTTNTATTAGPAPGGPAQPP-----------PTPQPSMADLQFSQLLGNL---- 608
               S           P P GP   P           P PQ     +    L G +    
Sbjct: 636 GPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPG 695

Query: 609 -------LGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPP 661
                  +GP GP  G  G   P      PG+      + +     + A  P  P     
Sbjct: 696 VKGDKGPMGPPGP-KGDQGEKGPRGLTGEPGMRGLPGAVGE--PGAKGAMGPAGPDGHQG 752

Query: 662 PAPEQQTMPPPG--SPSGGAGSPGGLGL 687
           P  EQ     PG   P G +G PG  GL
Sbjct: 753 PRGEQGLTGMPGIRGPPGPSGDPGKPGL 780



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 53/195 (27%), Positives = 70/195 (35%), Gaps = 41/195 (21%)

Query: 85   VERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP-GASV-----HDRNANSYVMVGTF 138
            V R    +   S    G GS  A    G   G RGP G  +     +   A   +  G  
Sbjct: 1301 VRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNG 1360

Query: 139  NLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQPPP 198
             L     A D+  N E A   SE   R  + Q M   +Q          GP     QP P
Sbjct: 1361 GLLGADFAGDLDYN-ELAVRVSESMQRQGLLQGMAYTVQ----------GPP---GQPGP 1406

Query: 199  Q-PPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL-TPGP----APAG 252
            Q PP ++    A S+ T++ ++         +     +  P Q  E+ TPGP     PAG
Sbjct: 1407 QGPPGISKVFSAYSNVTADLMDF-------FQTYGAIQGPPGQKGEMGTPGPKGDRGPAG 1459

Query: 253  PTPAPETNAPNHPSP 267
            P        P HP P
Sbjct: 1460 P--------PGHPGP 1466


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 87/312 (27%), Positives = 110/312 (35%), Gaps = 61/312 (19%)

Query: 388  PPPTPNAEAPPPGPGQASSVAPSSTNV------ESSAEGAP-PPGPAPPPATSHPRVIRI 440
            PPP P  +  P     A S +PS++ V       ++ +GAP PP P PPP    P     
Sbjct: 795  PPPPP--QLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMP----- 847

Query: 441  SHQSVEPVVMMHMNIQDSGTQPGGVPSA---PTGPLGPPGHGQTLGQQVPGFPTAPTRVV 497
                    + +  +++  G +P   PS    P   L PPG  Q L   +   P AP    
Sbjct: 848  --------LQLEAHLRSHGLEPAA-PSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTG 898

Query: 498  IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQ------PVLVAQ 551
            +    PP +    P G   S + QG        L  +       LL        P +   
Sbjct: 899  VG---PPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSIC--FPDSLLQDEERSFFPTMEEM 953

Query: 552  GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQ-PSMADLQFSQLLGNLLG 610
               G A     A      G       AGP PG PA  P  P  P  A         +  G
Sbjct: 954  FGGGAADDYGKAGPPEDEGDPKAG--AGPPPGPPAYDPYGPYCPGRA---------SGAG 1002

Query: 611  PAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMP 670
            P  PG G      P +   +   P  L            A PPPPPPPPPPPAP  +   
Sbjct: 1003 PETPGLGLDPNKPPELPSTVNAEPLGL-----IQSGPHQAAPPPPPPPPPPPAPASE--- 1054

Query: 671  PPGSPSGGAGSP 682
                P GG  SP
Sbjct: 1055 ----PKGGLTSP 1062



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 42/137 (30%), Positives = 51/137 (37%), Gaps = 32/137 (23%)

Query: 546  PVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLL 605
            P+  A   PG  PPP P   SA++  T         P     P PTPQP           
Sbjct: 1423 PLAPAAAVPG--PPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQ---------- 1470

Query: 606  GNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPE 665
                 P  P         P    A+P  P  +         T ++PPPPP PPPPPPA  
Sbjct: 1471 -----PPPP--------PPPPQPALPSPPPLVA-------PTPSSPPPPPLPPPPPPAMP 1510

Query: 666  QQTMPPPGSPSGGAGSP 682
                PPP + +  A  P
Sbjct: 1511 SPPPPPPPAAAPLAAPP 1527



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 107/420 (25%), Positives = 143/420 (34%), Gaps = 100/420 (23%)

Query: 383 GNGTRPPPTPNAEAPPPGPG----QASSVAPSSTNVESSAEGAPP--------PGPAPPP 430
           G    PP  P    PPP P     Q + +A SS    ++ + +P         PGP PPP
Sbjct: 220 GPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGP-PPP 278

Query: 431 ATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPG-F 489
             + PR         +  V+ H     S   P         P  PP H         G +
Sbjct: 279 ERALPR---------QDTVIKHYQRPASAQPP---------PPPPPAHALQHYLSCGGSY 320

Query: 490 PTAPTRVVIA-------RPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG-- 540
           P+   R  +A        P+P    PS  G    +    G   G  A+      G  G  
Sbjct: 321 PSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGY 380

Query: 541 -QLLMQP-VLVAQGTPGMA------PPPAPATAS---------ASAGTTNTATTAGPAPG 583
             ++  P     +G  G A      PPP  +TA+         A+A  T  A+ AG A G
Sbjct: 381 RPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGA-G 439

Query: 584 GPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDF 643
           G A  P  PQ              LLGP   G G  G  +  ++ A    P++  G    
Sbjct: 440 GQAYSPGQPQ-------------GLLGPQAYGQGFGGGQAQDLSKA----PSYSGG---- 478

Query: 644 LQATQTAPPPPPPPPPPPPAPEQQTMPP---PGSPSGGAGSP------GGLGLESLSPEF 694
                  PP PP  PPPP     Q+  P    G   G  G P         GL + SP  
Sbjct: 479 -------PPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSL 531

Query: 695 -FTSVVQGVLSSLLGSLGARA---GSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLS 750
            +++     LS   G  G  +   G   S +  I+ L        P   G+ G  G  LS
Sbjct: 532 SYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLS 591



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 70/262 (26%), Positives = 89/262 (33%), Gaps = 75/262 (28%)

Query: 470  TGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPP-----VSGTLQ--- 521
            T PL PP       + VP  P+ P R +  +P PP A P+ P  PP     + G L+   
Sbjct: 1304 TPPLSPP-------KSVP--PSVPARGL--QPQPP-ATPAVPHPPPSGAFGLGGALEAAE 1351

Query: 522  --GAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASA---------- 569
              G GLG  +   ++   L   L   P   +     +A       + +SA          
Sbjct: 1352 SEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLA 1411

Query: 570  GTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVA 629
            G  +T+T  GP P  PA   P P P                P  P A  +G   P +   
Sbjct: 1412 GPKDTSTPDGP-PLAPAAAVPGPPPL---------------PGLPSANSNGTPEPPLLEE 1455

Query: 630  MPGV---PAFLQGMTDFLQATQTAPPPPPPPPPP---------------PPAPEQQTMPP 671
             P     PA            Q  PPPPPPPP P               PP P     PP
Sbjct: 1456 KPPPTPPPA---------PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPP 1506

Query: 672  PGSPSGGAGSPGGLGLESLSPE 693
            P  PS     P      +  PE
Sbjct: 1507 PAMPSPPPPPPPAAAPLAAPPE 1528



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 78/343 (22%), Positives = 109/343 (31%), Gaps = 47/343 (13%)

Query: 376 GTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPG---PAPPPAT 432
           G T   +G  T P       A   G G    +            GA   G   P PP +T
Sbjct: 353 GATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRST 412

Query: 433 SHPRVIRISHQSVEPVVMMHMNIQDSGTQPGG----VPSAPTGPLGPPGHGQTLGQQVPG 488
           + P+      QS+      +   + SG    G     P  P G LGP  +GQ       G
Sbjct: 413 ATPKC-----QSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQ-------G 460

Query: 489 FPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVL 548
           F     + +   P+     P  P GPP  G         +    Q+  G+ G+    P  
Sbjct: 461 FGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLY-GVQGEPYPGPAA 519

Query: 549 VAQGTPGMAPPPAPATASASA----------------GTTNTATTAGPAPGGPA--QPPP 590
            +QG P  +P  + +T  + A                G  + +    P    PA  +PP 
Sbjct: 520 HSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPG 579

Query: 591 TPQPSMADLQFSQLLGNLLGPAGPGAGG--------SGVASPTITVAMP-GVPAFLQGMT 641
              P       S +L +    A PGAG          G    +  +A P G PA      
Sbjct: 580 VGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDE 639

Query: 642 DFLQATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGG 684
           +FL       P PP          +          GG+G  GG
Sbjct: 640 EFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGG 682



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 85/358 (23%), Positives = 120/358 (33%), Gaps = 47/358 (13%)

Query: 399 PGPGQA--SSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQS----------VE 446
           PGP +   S   P S+   SS+  +    PA   +   P    +S Q           + 
Sbjct: 125 PGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLS 184

Query: 447 PVVMMHMNIQDSGTQPGGVPS---APTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTP 503
           P  ++H+    + T P  +     A  G LGP G G     Q P +   P       P P
Sbjct: 185 PHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPA---QTPPYRPGPPDP----PPP 237

Query: 504 PQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGT-------PGM 556
           P+  P+       S     A   ++  L        G    +  L  Q T       P  
Sbjct: 238 PRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPAS 297

Query: 557 A-PPPAPATASA-----SAGTT-----NTATTAGPAPGGPAQPPPTPQPSMADLQFSQL- 604
           A PPP P  A A     S G +     + A  A    GG    P   +PS A    +   
Sbjct: 298 AQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAG 357

Query: 605 -LGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPA 663
             G   GP   G GG+G         +   P +  G   +  A   A  PPPP     P 
Sbjct: 358 ASGRATGPEAAGGGGAGGGGGGYRPIIQS-PGYKTGKGGYGAAAGGATRPPPPRSTATPK 416

Query: 664 PEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIA 721
            +    P     +G A   GG G ++ SP       QG+L       G   G ++ ++
Sbjct: 417 CQSLGGPAAAYATGKASGAGGAGGQAYSP----GQPQGLLGPQAYGQGFGGGQAQDLS 470



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 23/67 (34%), Positives = 28/67 (41%)

Query: 189  PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
            PQP    PPPQP   +P P+   + +S P     PP  P          PA  P   P  
Sbjct: 1469 PQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPE 1528

Query: 249  APAGPTP 255
             PA P+P
Sbjct: 1529 EPAAPSP 1535



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 71/304 (23%), Positives = 93/304 (30%), Gaps = 35/304 (11%)

Query: 374  NVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATS 433
            +V  +V   G   +PP TP    PPP        A  +   E    G P P         
Sbjct: 1312 SVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELK 1371

Query: 434  HPRVIRISHQS-VEPVVMMHMNIQDS------------------GTQPGGVPSAPTGPL- 473
                   S  S  E  V  + ++Q+S                   + P G P AP   + 
Sbjct: 1372 RNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVP 1431

Query: 474  GPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQ 533
            GPP           G P  P       PTPP A    P  PP     Q A       +A 
Sbjct: 1432 GPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAP 1491

Query: 534  MVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQ 593
              S         P L     P M  PP P   +A+         A P+P  P  P   P 
Sbjct: 1492 TPSSPP-----PPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546

Query: 594  PSMADLQFSQLLGNLLGPAGPGAGGSGV--ASPTITVAMPGVPAFLQGMTDFLQATQTAP 651
                  + + + G     AG  +GG G+        +    +P+          A QT  
Sbjct: 1547 HLAKKQETAAVCGETDEEAGE-SGGEGIFRERDEFVIRAEDIPS-------LKLALQTGR 1598

Query: 652  PPPP 655
             PPP
Sbjct: 1599 EPPP 1602



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 80/361 (22%), Positives = 108/361 (29%), Gaps = 52/361 (14%)

Query: 187  GGPQPQ--HSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
            G P+P     +PPP PP   P P         P +   P   P+ A       P   P  
Sbjct: 1446 GTPEPPLLEEKPPPTPP-PAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504

Query: 245  TPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAATTDYN 304
             P   P+ P P P   AP    P E      E   L       L +  E       TD  
Sbjct: 1505 PPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEE 1564

Query: 305  NNHEG-----REEDQRLINLVG-ESLRLLGNT---------------------------- 330
                G     RE D+ +I      SL+L   T                            
Sbjct: 1565 AGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQ 1624

Query: 331  FVALSDLRCNLACTPPRHLHV-VRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPP 389
            F A S+          R+  + V+ + +      ++  A          V  +G    P 
Sbjct: 1625 FCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPV 1684

Query: 390  PTPNAEAPPP-GPG-QASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
                + APPP  P        P  T  E   E  P      PPA   P ++R   +  E 
Sbjct: 1685 SAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEK 1744

Query: 448  VVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQAR 507
              +        G +P     A +G    P      GQ       A +R+  ARPT  +A 
Sbjct: 1745 EKVTR------GERPLRGERATSGRQTRPERSLATGQ------PATSRLPKARPTKVKAE 1792

Query: 508  P 508
            P
Sbjct: 1793 P 1793



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 55/221 (24%), Positives = 81/221 (36%), Gaps = 50/221 (22%)

Query: 238  PAQNPELTPGPAPAG---PTPAPETNAPNHPSPAEYVEVLQELQRLES------------ 282
            P   P+  P   PA    P P P T A  HP P+    +   L+  ES            
Sbjct: 1306 PLSPPKSVPPSVPARGLQPQP-PATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCK 1364

Query: 283  RLQPFLQRYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLA 342
            RL   L+R  E L + ++ + ++  + R+  + + + +            AL D      
Sbjct: 1365 RLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAIS-----------ALDD------ 1407

Query: 343  CTPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGT--------RPPPTPNA 394
              PP  L   +  S    P +   AA+P    +    +   NGT        +PPPTP  
Sbjct: 1408 --PP--LAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPP 1463

Query: 395  EA-----PPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPP 430
                   PPP P       PS   + +    +PPP P PPP
Sbjct: 1464 APTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504



 Score = 38.5 bits (88), Expect = 0.036
 Identities = 39/143 (27%), Positives = 48/143 (33%), Gaps = 17/143 (11%)

Query: 187 GGPQPQHSQPPPQPPAVTPEPVALSSQTSEPV---------ESEAPP---REPMEAEEVE 234
           G PQP    PPP PP        L S   EP          ES  PP   +E + A E  
Sbjct: 831 GAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPL 890

Query: 235 ERAPAQ---NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRY 291
             AP      P  + G  PAG   +P       P       +      L+   + F    
Sbjct: 891 PPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTM 950

Query: 292 YEVLGAAATTDYNNNHEGREEDQ 314
            E+ G  A  DY     G  ED+
Sbjct: 951 EEMFGGGAADDYGK--AGPPEDE 971



 Score = 37.4 bits (85), Expect = 0.081
 Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 16/86 (18%)

Query: 188  GPQPQHSQPPPQPPAVTPEPVALSSQTSEP--VESEAPPREPMEAEEVEERAPAQNPELT 245
            GP    +   P PP +   P A S+ T EP  +E + PP  P          PA  P+  
Sbjct: 1421 GPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPP----------PAPTPQPQ 1470

Query: 246  PGPAPAGPTPA----PETNAPNHPSP 267
            P P P  P PA    P   AP   SP
Sbjct: 1471 PPPPPPPPQPALPSPPPLVAPTPSSP 1496



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 46/205 (22%), Positives = 70/205 (34%), Gaps = 18/205 (8%)

Query: 83  HLVER-APPQTHLPSGASSGTGSASATHG------GGSPPGTRGPGASVHDRNANSYVMV 135
           HL++  +PP+T    G     G+A A+ G       G PPGT    A    +  +   ++
Sbjct: 645 HLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVI 704

Query: 136 GTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQ 195
            T     +G+   + + + +   + +   R       +              G   Q S 
Sbjct: 705 RTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSP 764

Query: 196 PPPQPPA--VTPEPVALSSQTSEP-VESEAPPREPMEAEEVEERAPAQNPE--------L 244
           PPP P A    P P  L  +   P +    PP  P     V   AP+ +P         L
Sbjct: 765 PPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824

Query: 245 TPGPAPAGPTPAPETNAPNHPSPAE 269
            P      P P P    P  P P +
Sbjct: 825 EPATRDGAPQPPPPPPPPPPPMPLQ 849



 Score = 32.3 bits (72), Expect = 2.6
 Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 25/71 (35%)

Query: 385  GTRPPPTPNAEAP--PPGPGQASSVAP----------------SSTNVESSA-------E 419
            G  PPP P A  P  P  PG+AS   P                S+ N E          +
Sbjct: 977  GAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQ 1036

Query: 420  GAPPPGPAPPP 430
             APPP P PPP
Sbjct: 1037 AAPPPPPPPPP 1047



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 3/37 (8%)

Query: 649  TAPPPPPP-PPPPPPAPEQQT--MPPPGSPSGGAGSP 682
            +APPP  P PPP P  PE+ T   PP  +P      P
Sbjct: 1690 SAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEP 1726



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 22/66 (33%), Positives = 27/66 (40%), Gaps = 7/66 (10%)

Query: 634  PAFLQGMTDFLQATQTAPPPPPPP--PPPPPAPEQQTMPPPGSPSGGAGS-----PGGLG 686
            P +  G+T  L   ++ PP  P     P PPA      PPP    G  G+       GLG
Sbjct: 1297 PLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLG 1356

Query: 687  LESLSP 692
            L   SP
Sbjct: 1357 LGCPSP 1362



 Score = 30.8 bits (68), Expect = 7.6
 Identities = 37/156 (23%), Positives = 59/156 (37%), Gaps = 22/156 (14%)

Query: 933  YVRRVGDPPQPLPEEPMEVQGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSR- 991
            YVR     P   P  P+   G        Q +N   A G++A    +  PPP PE   + 
Sbjct: 1658 YVRVCARKPWHRPPVPVRRSG--------QAKNPVSAGGSSAPPPKAPAPPPKPETPEKT 1709

Query: 992  -----DEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPL-SDAYLSGMPAKRR 1045
                  EQ   +A  EP A   P    P ++++ + ++  + + PL  +   SG   +  
Sbjct: 1710 TSEKPPEQTPETAMPEPPAPEKPSLLRP-VEKEKEKEKVTRGERPLRGERATSGRQTRPE 1768

Query: 1046 KTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLSR 1081
            +++    P      A SR  KA   +    P    R
Sbjct: 1769 RSLATGQP------ATSRLPKARPTKVKAEPPPKKR 1798



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 24/74 (32%), Positives = 29/74 (39%), Gaps = 17/74 (22%)

Query: 636  FLQGMTDFLQATQTAPP-----------PPPPPPPPPPAPEQQTMPP-----PGSPSGGA 679
            F+    DFL++ +  PP           PP   PP  PA   Q  PP     P  P  GA
Sbjct: 1281 FMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGA 1340

Query: 680  GSPGGLGLESLSPE 693
               GG  LE+   E
Sbjct: 1341 FGLGG-ALEAAESE 1353


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 156/648 (24%), Positives = 205/648 (31%), Gaps = 123/648 (18%)

Query: 94   LPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDVHINM 153
            LP+       +A+A H GG           + ++N    + +G    P  G A   HI +
Sbjct: 489  LPANVGGQILAAAAPHTGGQLIAN----PILTNQNLAGPLSLGPVLAPHSG-AHSAHI-L 542

Query: 154  EQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVT--------- 204
              APIQ        + Q  +  +   L+      G  P  SQP P  PA T         
Sbjct: 543  SAAPIQ--------VGQPALFQMPVSLA-----AGSLPTQSQPAPAGPAATTVLQGVTLP 589

Query: 205  PEPVALSSQTSEPVESEAPPREPMEAEEVEERAPA-QNPELTPGPAPAGPTPAPETNAPN 263
            P  VA+ +     V+   P     EA  V    PA Q P     P P G         P 
Sbjct: 590  PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649

Query: 264  HPSPAEYVEVLQELQRLESRLQPFLQRYYE--VLG--------AAATTDYNNNHEGREED 313
             P+P    +     Q    +  P L    E  VLG        A  T D       +E  
Sbjct: 650  APTP----QAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERS 705

Query: 314  QRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTTPMVLQQAAIPIQI 373
            Q+ ++  G  L +  +  V+           PP              P      A P+  
Sbjct: 706  QQPLSAEGPHLSVPASVIVS----------APP--------------PAQDPAPATPVAK 741

Query: 374  NVGTTVTMTGNGTRPPPTPN--AEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPA 431
              G       +   P P P   A AP  GPG +SS +         +   P P P  PP+
Sbjct: 742  GAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS 801

Query: 432  TSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPT 491
                R   +S    EP +      Q   T PG         LG P          PG P 
Sbjct: 802  RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF--VIQNQLGVPPPASNPAPTAPGPPQ 859

Query: 492  APTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQ 551
             P R     P  P   P  P  PP S +   A     +S     +    QL   P   +Q
Sbjct: 860  PPLRPQSQPPEGPL--PPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPP---SQ 914

Query: 552  GTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPT------------PQPSMADL 599
            G P  +P P P                 P P  P  PPP             PQP     
Sbjct: 915  G-PHKSPTPPPTLHLV------------PEPAAPPPPPPRTFQMVTTPFPALPQPKALLE 961

Query: 600  QFSQLLGNLLGPAGPGAGGSGVASPTIT----VAMPGVPAFLQGMTDFLQATQTAPPPPP 655
            +F Q+   ++      AGG+  A  T T    +  P     + G       T TAP   P
Sbjct: 962  RFHQVPSGII--LQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAP--SGTPTAPSHAP 1017

Query: 656  PPPP------PPPAPEQQ--------TMPPPGSPSGGAGSPGGLGLES 689
             P P      PP  P +         T+    + S G G P GL  ES
Sbjct: 1018 APAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYES 1065



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 134/566 (23%), Positives = 190/566 (33%), Gaps = 110/566 (19%)

Query: 189 PQPQHSQP----PPQPPAVTPEPVALSSQT----SEPVESEAPPREPMEAEEVEERAPAQ 240
           P P   +P    PP+   +TP+P A +  T     EP      P+ P     +      Q
Sbjct: 348 PTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQ 407

Query: 241 NPELTPGPAPA------GPTPAPETNA-----PNHPSPAEYVEVLQELQRLESRLQPFL- 288
           N  L+  PAPA         PA  T A     P   S    V +L +   +    Q  L 
Sbjct: 408 NVVLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLP 467

Query: 289 -QRYYEVLGAAATTDYNNNHEGREEDQRL----INLVGESL---------RLLGNTFVAL 334
            Q  + + GA A           +  Q+L     N+ G+ L         +L+ N  +  
Sbjct: 468 GQNQFLLPGAPAV----------QLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTN 517

Query: 335 SDLRCNLACTPPRHLHVVRPMSH--------------YTTPMVLQQAAIPIQIN---VGT 377
            +L   L+  P    H     +H              +  P+ L   ++P Q      G 
Sbjct: 518 QNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGP 577

Query: 378 TVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRV 437
             T    G   PP+  A    P  G      P++   E++      P P  PPA S P  
Sbjct: 578 AATTVLQGVTLPPSAVAMLNTPD-GLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLP 636

Query: 438 IRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVV 497
           + +               Q    QP   P APT     P    T  Q  PG  ++P ++V
Sbjct: 637 LGLQ--------------QPQAQQP---PQAPTPQAAAPPQATT-PQPSPGLASSPEKIV 678

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557
           + +P  P A P+         T     +      +Q      G  L  P  V    P  A
Sbjct: 679 LGQP--PSATPT------AILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPA 730

Query: 558 PPPAPATASASAG-----TTNTATTAGPAPGGPAQPP-----PTPQPSM---ADLQFSQL 604
             PAPAT  A          ++  +  PAP  PA  P     P+  PS+   A L  S  
Sbjct: 731 QDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPH 790

Query: 605 LGN---LLGPAGPGAGGSGVASPTITVAM-----PGVPAFLQGMTDFLQATQTAPPPPPP 656
           L +      P+ P +    V+ P     +     P  P  L G+   +Q     PPP   
Sbjct: 791 LPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF-VIQNQLGVPPPASN 849

Query: 657 PPPPPPAPEQQTMPPPGSPSGGAGSP 682
           P P  P P Q  + P   P  G   P
Sbjct: 850 PAPTAPGPPQPPLRPQSQPPEGPLPP 875



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 106/440 (24%), Positives = 146/440 (33%), Gaps = 102/440 (23%)

Query: 365 QQAAIPIQINVGTTVTMTGNG----------TRPPPTPNAEAPPPGPGQASSVAPSSTNV 414
           Q A + IQ N+   V  T NG          + P  TP+ +     PG  SS    + NV
Sbjct: 283 QGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNV 342

Query: 415 ESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGP-- 472
                  P P    P     P++ +++ +   P     + IQ    +PG +P  P  P  
Sbjct: 343 --ILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGAT-LTIQG---EPGALPQQPKAPQN 396

Query: 473 -----LGPPGHGQTLGQQVPGFPTAPTRVVI-----------ARPTPPQA--RPSH---- 510
                 G  G    L     GFP    +  +           A P PP A  +P      
Sbjct: 397 LTFMAAGKAGQNVVLS----GFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLL 452

Query: 511 ----------------------PGGPPVSGTLQGAGLGTNAS---LAQMVSGLVGQLLMQ 545
                                 PG P V    Q + L  N     LA       GQL+  
Sbjct: 453 NQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIAN 512

Query: 546 PVLVAQGTPG---MAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFS 602
           P+L  Q   G   + P  AP + + SA   + A            P    QP++  +  S
Sbjct: 513 PILTNQNLAGPLSLGPVLAPHSGAHSAHILSAA------------PIQVGQPALFQMPVS 560

Query: 603 QLLGNLL-----GPAGPGAGG--SGVASPTITVAM---------PGVPAFLQGMTDFLQA 646
              G+L       PAGP A     GV  P   VAM         P  PA   G    +  
Sbjct: 561 LAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLT 620

Query: 647 TQTAPPPPPPPPPPPPAPEQQ--TMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLS 704
            Q AP  PP    P P   QQ     PP +P+  A +P        SP   +S  + VL 
Sbjct: 621 VQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLG 680

Query: 705 SLLGSLGARAGSSESIAAFI 724
               +      + +S+  F+
Sbjct: 681 QPPSATPTAILTQDSLQMFL 700



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 137/599 (22%), Positives = 199/599 (33%), Gaps = 132/599 (22%)

Query: 189  PQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPELTPGP 248
            PQ   S  P   PA +      +   +    S AP   PM A  +    PA+N       
Sbjct: 983  PQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASN- 1041

Query: 249  APAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQP-----FLQRYYEVLGAAATTDY 303
             P        ++ P  PS  +Y   L  L++    LQP     FL+  ++  G+    DY
Sbjct: 1042 LPTLNVAKAASSGPGKPSGLQYESKLSGLKK-PPTLQPSKEACFLEHLHKHQGSVLHPDY 1100

Query: 304  NNNHEGREED-QRLI---------------NLVGE-----SLRLLGNTFVALSDLRCNL- 341
                   E+   RL+               + V E     S +LL  T   L+  R  L 
Sbjct: 1101 KTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLL 1160

Query: 342  ----ACTPPRHLHVVRPM---SHYTTPMVLQQAA-------IPIQINVGTTVTMTGNGTR 387
                  +P   + ++  M      TT  + +Q A       +    ++G  +  +  G R
Sbjct: 1161 EESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHR 1220

Query: 388  PP-------PTPNAEAPPP------------GPG--------QASSVAPSSTNVESSA-- 418
             P         P A   PP            G G        +ASS   SS++  S+A  
Sbjct: 1221 LPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASS 1280

Query: 419  ----EGAPPPGPAPPPATSHPRVIRIS-----HQSVEPVVMMHMNIQDSGTQPGGVPSA- 468
                E  P P    PP  ++    RI       Q      ++H    D   QP   P+  
Sbjct: 1281 LDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATL 1340

Query: 469  ------PTGPLGPPGHGQTLGQQVPGFPTAPTRVVIAR----PTPPQAR--------PSH 510
                  P  P  PP  GQ  G      P AP R  +      P  P  +        P  
Sbjct: 1341 KVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGA 1400

Query: 511  PGGPPVSGTLQGAGLGTNASLAQMVSGLVGQL-LMQPVLVAQGTPGMAPPPAPATASASA 569
            P G P      G+     A + +  SGL+ +L  ++  L  +   G  PPP PA ASA+ 
Sbjct: 1401 PEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKG--PPPEPA-ASAAQ 1457

Query: 570  GTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVA 629
            GT +    A   P  PA+   +  P +    FS                    SP     
Sbjct: 1458 GTGDPDWEAPGLP--PAKRRKSESPDVDQASFSS------------------DSPQDDTL 1497

Query: 630  MPGVPAFLQGMTDFLQATQTAPPPPPP-------PPPPPPAPEQQTMPPPGSPSGGAGS 681
               + + +  + +  QA    P P  P       P  PPP    +   PP S +GG G+
Sbjct: 1498 TEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAY-PPSSHNGGLGA 1555



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 133/608 (21%), Positives = 186/608 (30%), Gaps = 153/608 (25%)

Query: 78   GGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGT 137
            G    H++  AP Q   P+        A+ +    S P   GP A+         V+ G 
Sbjct: 535  GAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATT--------VLQGV 586

Query: 138  FNLPSDGSAVDVHINMEQ--APIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQHSQ 195
               PS  + ++    + Q   P  +      V+           +S     G  QPQ  Q
Sbjct: 587  TLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ 646

Query: 196  PP----PQ----PPAVTPEPVALSSQTSEPVESEAPP----------------------R 225
            PP    PQ    P A TP+P    + + E +    PP                      +
Sbjct: 647  PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706

Query: 226  EPMEAEEVEERAPAQNPELTPGPA--PAGPTP----------APETNAPNHPSPAEYVEV 273
            +P+ AE      PA      P PA  PA  TP          AP++ A   P+PA  +  
Sbjct: 707  QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQA--SPAPAPQIPA 764

Query: 274  LQELQRLESRLQPFLQRYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVA 333
               L+       P L     +     +    + H  R   +                   
Sbjct: 765  AAPLKGPGPSSSPSLPHQAPL---GDSPHLPSPHPTRPPSR------------------- 802

Query: 334  LSDLRCNLACTPPRHLHVVRPMSH---YTTPMVLQQAAIPIQINVGTTVTMTGNGTRPP- 389
                       P R   V RP S    +  P       +P     G  V     G  PP 
Sbjct: 803  ----------PPSRPQSVSRPPSEPPLHPCPPPQAPPTLP-----GIFVIQNQLGVPPPA 847

Query: 390  --PTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
              P P A  PP  P +  S  P         EG  PP P  PP+++   V   S  S   
Sbjct: 848  SNPAPTAPGPPQPPLRPQSQPP---------EGPLPPAPHLPPSSTSSAVASSSETSSRL 898

Query: 448  VVMMHMNIQ----------DSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAP-TRV 496
                  + Q           S T P  +   P     PP   +T       FP  P  + 
Sbjct: 899  PAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKA 958

Query: 497  VIAR----PTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQG 552
            ++ R    P+    +    G P    T    G  T+ + + +VSG       Q       
Sbjct: 959  LLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSG-------QAPSGTPT 1011

Query: 553  TPGMAPPPAPATA--------------SASAGTTNTATTAGPAPGGPA-----------Q 587
             P  AP PAP  A              +++  T N A  A   PG P+           +
Sbjct: 1012 APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071

Query: 588  PPPTPQPS 595
             PPT QPS
Sbjct: 1072 KPPTLQPS 1079



 Score = 38.1 bits (87), Expect = 0.047
 Identities = 67/287 (23%), Positives = 94/287 (32%), Gaps = 63/287 (21%)

Query: 457 DSGTQPGGVPSAPTGPLGP----PGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPG 512
           D G  P G   A     GP    PG    LG Q P  PT  T   +    PPQ   +   
Sbjct: 138 DGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGP--PTVLTHQALV---PPQDVVNK-- 190

Query: 513 GPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP------------GMAPPP 560
              V   LQ  GLG               + +QP+   QG P            G+AP  
Sbjct: 191 ALSVQPFLQPVGLGN--------------VTLQPIPGLQGLPNGSPGGATAATLGLAPIQ 236

Query: 561 APATASASAGTTNTATTAGPAP--------GGPAQPPPTP-------------QPSMADL 599
                  +  T  +   A   P         GP++P                 Q +++  
Sbjct: 237 VVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAA 296

Query: 600 QFSQLLGN-LLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPP 658
             + L GN + G AG  +  +G  S       PG+ +        +   +T  P  P P 
Sbjct: 297 VATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPA 356

Query: 659 PPPPAPEQQTMPPPGSPSGGA----GSPGGLGLESLSPEFFTSVVQG 701
              P    Q  P P +P+G      G PG L  +  +P+  T +  G
Sbjct: 357 GVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAG 403



 Score = 35.0 bits (79), Expect = 0.40
 Identities = 46/191 (24%), Positives = 73/191 (38%), Gaps = 35/191 (18%)

Query: 90   PQTHLPSGASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGSAVDV 149
            P  HLP+      G A     GGSP  T    +S    +++S     + +   DG     
Sbjct: 1238 PPPHLPTKLVIRHGGA-----GGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMP-- 1290

Query: 150  HINMEQAPIQS-EPRVRLVMAQHMIRDIQTLLSRMECRGGPQPQH-----------SQPP 197
              +  + PI++ E R R+ +   + ++    LS++       P H           ++PP
Sbjct: 1291 --SRNRPPIKTYEARSRIGLKLKIKQEAG--LSKVVHNTALDPVHQPPPPPATLKVAEPP 1346

Query: 198  PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQN-----------PELTP 246
            P+PP   P P    + T +     AP R+P+       R P +            PE TP
Sbjct: 1347 PRPP-PPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTP 1405

Query: 247  GPAPAGPTPAP 257
                 G +PAP
Sbjct: 1406 AGRARGGSPAP 1416


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
           [Homo sapiens]
          Length = 1125

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 94/342 (27%), Positives = 123/342 (35%), Gaps = 71/342 (20%)

Query: 354 PMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPP--PGPGQASSVAPSS 411
           P+S    P+ +    IP+   +          T PPP    + PP  PGP    ++ P +
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPI----------TVPPP----QVPPHQPGPPVVGALQPPA 699

Query: 412 TNVESSAEGAPPPG--PAPPPATSHPRVIRISHQSVE-----------PVVMMHMNIQDS 458
               +   G PPPG  P  PP    P  +R     +            P +   ++I   
Sbjct: 700 F---TPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPP 756

Query: 459 GTQPGGVPSAPTGPLGPPGHGQTL---GQQVPGFPTAPTRVVIARPTPPQARPSHPGGPP 515
            T P  +P+  +G  G    G ++   G  VP  P APT +    PTPP  +P       
Sbjct: 757 HTPPISIPNLVSGARGNAESGDSVKMYGSAVP--PAAPTNL----PTPPVTQPVS----- 805

Query: 516 VSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVA-QGTPGMAPPPA---PATASASAGT 571
           + GT QG   G    L    +GL+G    +P L+  Q  PGM PP     P         
Sbjct: 806 LLGT-QGVAPGPVIGLQAPSTGLLGA---RPGLIPLQRPPGMPPPHLQRFPLMPPRPMPP 861

Query: 572 TNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAG-PGAGGSGVASPTITVAM 630
                   P PGG A PPP               G  + P G PG GG G          
Sbjct: 862 HMMHRGPPPGPGGFAMPPPHGMKGPFPPH-----GPFVRPGGMPGLGGPGPG-------- 908

Query: 631 PGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTMPPP 672
           PG P    G     Q  Q     P P  P  P  +QQ  PPP
Sbjct: 909 PGGPEDRDGRQ---QPPQQPQQQPQPQAPQQPQQQQQQQPPP 947



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 79/298 (26%), Positives = 99/298 (33%), Gaps = 67/298 (22%)

Query: 461 QPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTL 520
           Q GG  ++ T P+ P      + + +P  P  P  V      PP   P H  GPPV G L
Sbjct: 643 QNGGAETSHTEPVSP------IPKPLP-VPVPPIPVPAPITVPPPQVPPHQPGPPVVGAL 695

Query: 521 QGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGP 580
           Q         +     G                PG+ PPP P       G        G 
Sbjct: 696 QPPAFTPPLGIPPPGFG----------------PGV-PPPPPPPPFLRPGFNPMHLPPGF 738

Query: 581 APGGP---------AQPPPTPQPSMADLQFSQLLGN--------LLGPAGPGAGGSGVAS 623
            P GP           PP TP  S+ +L  S   GN        + G A P A  + + +
Sbjct: 739 LPPGPPPPITPPVSIPPPHTPPISIPNL-VSGARGNAESGDSVKMYGSAVPPAAPTNLPT 797

Query: 624 PTIT--VAMPGVPAFLQGMTDFLQATQTA-------------PPPPPPP--------PPP 660
           P +T  V++ G      G    LQA  T              PP  PPP        PP 
Sbjct: 798 PPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPR 857

Query: 661 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSE 718
           P  P      PP  P GG   P   G++   P     V  G +   LG  G   G  E
Sbjct: 858 PMPPHMMHRGPPPGP-GGFAMPPPHGMKGPFPPHGPFVRPGGMPG-LGGPGPGPGGPE 913



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 45/157 (28%), Positives = 56/157 (35%), Gaps = 32/157 (20%)

Query: 377 TTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPR 436
           T VT T      PP P A  P       ++ AP++      A   PP  P   P     +
Sbjct: 283 TAVTTTAPAAAVPPAPTATVP-------AAAAPAA------ASPPPPQAPFGFPGDGMQQ 329

Query: 437 VIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRV 496
                HQ+++      M IQ         P     PL P G       Q+PGF   PT  
Sbjct: 330 PAYTQHQNMDQFQPRMMGIQQD-------PMHHQVPLPPNG-------QMPGFGLLPTP- 374

Query: 497 VIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQ 533
               P PP A+P  P  PPV    Q +    N  L Q
Sbjct: 375 ----PFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQ 407



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 35/139 (25%)

Query: 559 PPAPATASASAGTTNTATT--AGPAPGG-PAQPPPTPQPSMADLQFSQLLGNLLGPAGPG 615
           P  P    A  G   T+ T    P P   P   PP P P+   +   Q+  +  GP   G
Sbjct: 634 PKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVG 693

Query: 616 AGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPP----------------- 658
           A      +P + +  PG   F  G+          PPPPPPPP                 
Sbjct: 694 ALQPPAFTPPLGIPPPG---FGPGV----------PPPPPPPPFLRPGFNPMHLPPGFLP 740

Query: 659 --PPPPAPEQQTMPPPGSP 675
             PPPP     ++PPP +P
Sbjct: 741 PGPPPPITPPVSIPPPHTP 759



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 52/198 (26%), Positives = 63/198 (31%), Gaps = 31/198 (15%)

Query: 488 GFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPV 547
           G P  P +V    PT  QA P+     P     Q       A++AQ+     GQ L Q +
Sbjct: 153 GSPPPPVKVSSEPPT--QATPNSVPAVP-----QLPSSDAFAAVAQLFQTTQGQQLQQIL 205

Query: 548 LVAQGTPGMAPPPAPAT-----ASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFS 602
              Q  P    P +PA      A   A T    TT        A  PP  Q +  D    
Sbjct: 206 QTFQQPP---KPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFD---K 259

Query: 603 QLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPP 662
           +LL        P A        T  V      A               PP P    P   
Sbjct: 260 KLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAA-------------AVPPAPTATVPAAA 306

Query: 663 APEQQTMPPPGSPSGGAG 680
           AP   + PPP +P G  G
Sbjct: 307 APAAASPPPPQAPFGFPG 324



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 82/345 (23%), Positives = 112/345 (32%), Gaps = 60/345 (17%)

Query: 187 GGPQPQHSQPP---PQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPE 243
           GG +  H++P    P+P  V   P+ + +  + P   + PP +P        + PA  P 
Sbjct: 645 GGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVP-PPQVPPHQPGPPVVGALQPPAFTPP 703

Query: 244 L---TPGPAPAGPTPAPETN-----------APNHPSPAEYVEVLQELQRLESRLQPFLQ 289
           L    PG  P  P P P               P    P     +   +        P   
Sbjct: 704 LGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPI-- 761

Query: 290 RYYEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHL 349
                    +  +  +   G  E        G+S+++ G+     +    NL  TPP   
Sbjct: 762 ---------SIPNLVSGARGNAES-------GDSVKMYGSAVPPAAP--TNLP-TPP--- 799

Query: 350 HVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTG-NGTRPPPTPNAEAP--PPGPGQASS 406
            V +P+S   T  V   A  P+   +G     TG  G RP   P    P  PP   Q   
Sbjct: 800 -VTQPVSLLGTQGV---APGPV---IGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFP 852

Query: 407 VAPSSTNVESSAEGAPPPGP---APPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPG 463
           + P            PPPGP   A PP              V P  M    +   G  PG
Sbjct: 853 LMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGM--PGLGGPGPGPG 910

Query: 464 GVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARP 508
           G P    G   PP   Q   Q  P  P  P +    +P P Q  P
Sbjct: 911 G-PEDRDGRQQPPQQPQQ--QPQPQAPQQPQQQQQQQPPPSQQPP 952



 Score = 30.4 bits (67), Expect = 9.9
 Identities = 37/145 (25%), Positives = 56/145 (38%), Gaps = 33/145 (22%)

Query: 98  ASSGTGSASATHGGGSPPGTRGPGASVHDRNANSYVMVGTFNLPSDGS---AVDVHINME 154
           A + T  A+A     SPP  + P                 F  P DG    A   H NM+
Sbjct: 297 APTATVPAAAAPAAASPPPPQAP-----------------FGFPGDGMQQPAYTQHQNMD 339

Query: 155 QAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGG-----PQPQHSQP--PPQPPAVTPEP 207
           Q     +PR+  +    M   +    +      G     P P  +QP  PP PP   P  
Sbjct: 340 QF----QPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQ 395

Query: 208 VALSSQTSEPVESEAPPREPMEAEE 232
            +  +Q +EP+ ++ P ++ ME E+
Sbjct: 396 ASFQAQ-NEPL-TQKPHQQEMEVEQ 418


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 97/349 (27%), Positives = 117/349 (33%), Gaps = 84/349 (24%)

Query: 384 NGTRPPPTPNA-------EAPPPGPGQASSVAPSSTNVESSAEGAPP-------PGPAPP 429
           NG + PP P         + PP  PG      PS    E    G          PGPA P
Sbjct: 528 NGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGP 587

Query: 430 PATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGF 489
                P                     +SG      P    GP GPPG     G+  PG 
Sbjct: 588 RGERGPP-------------------GESGAAGPTGPIGSRGPSGPPGPDGNKGE--PGV 626

Query: 490 PTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLV 549
             A   V  A P+ P   P   G   + G     G G          GL G++       
Sbjct: 627 VGA---VGTAGPSGPSGLPGERGAAGIPG-----GKGEKGE-----PGLRGEIGNPGRDG 673

Query: 550 AQGTPGMAPPPAPATASASAGTTNTATTAGPA-----PG-----GPAQPPPTPQPSMA-- 597
           A+G PG    P PA A+   G    A  AGPA     PG     GPA P     P+ A  
Sbjct: 674 ARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAG 733

Query: 598 --------DLQFSQLLGNLLGPAGP-----GAGGSGVASPTITVAMPGVPAFLQGMTDFL 644
                     +  +    ++GP GP      AG +G   P  +    G P    GMT F 
Sbjct: 734 QPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPP----GMTGFP 789

Query: 645 QATQTAPPPPP-----PPPPPPPAPEQQTMPPPG--SPSGGAGSPGGLG 686
            A     PP P     PP PP PA ++    P G   P G  G  G +G
Sbjct: 790 GAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVG 838



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 86/344 (25%), Positives = 109/344 (31%), Gaps = 88/344 (25%)

Query: 389 PPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPV 448
           P  P  +  P  PG+      + T  ++ A G P  G         P   R S  SV PV
Sbjct: 192 PGAPGVKGEPGAPGE------NGTPGQTGARGLP--GERGRVGAPGPAGARGSDGSVGPV 243

Query: 449 VMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPT-RVVIARPTPPQAR 507
                 I  +G  P G P AP    GP G    +G   P  P  P   V +   + P   
Sbjct: 244 GPAGP-IGSAG--PPGFPGAP----GPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGP 296

Query: 508 PSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567
           P +PG   ++G    AGL           G+ G         A G PG    P P  A+ 
Sbjct: 297 PGNPGANGLTGAKGAAGL----------PGVAG---------APGLPGPRGIPGPVGAAG 337

Query: 568 SAGTTNTATTAGPA----------------PGGPAQP-----------------PPTP-- 592
           + G        GPA                P GP  P                 PP P  
Sbjct: 338 ATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPG 397

Query: 593 ---QPSMADLQFSQLLGNLLGPAGP--GAGGSGVASPTITVAMPGVPAFLQGMTDFLQAT 647
               P    L  +     ++GP G    +G +GV  P      PG P         L   
Sbjct: 398 LRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPG--------LMGP 449

Query: 648 QTAPPPPPPPPP-----PPPAPEQQTMPPPGSPSGGAGSPGGLG 686
           +  P  P    P     P   P     P P  P+G  G PG +G
Sbjct: 450 RGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIG 493



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 87/327 (26%), Positives = 107/327 (32%), Gaps = 40/327 (12%)

Query: 385 GTRPPPTPNAEAPPPGP----GQASSVAPSSTNVESSAEGAP----PPGPAPPPATSHPR 436
           G R PP  +  A P GP    G +    P     E    GA     P GP+  P      
Sbjct: 589 GERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAA 648

Query: 437 VIRISH-QSVEPVVMMHMNI--QDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAP 493
            I     +  EP +   +    +D      G   AP GP G  G     G   P  P  P
Sbjct: 649 GIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAP-GPAGATGDRGEAGAAGPAGPAGP 707

Query: 494 TRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGT 553
                 R     A P+   GP  +    GA     A   +  +G+VG     PV  A G 
Sbjct: 708 RGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPT--GPVGAA-GP 764

Query: 554 PGMAPPPAPATASASAGTTN-------TATTAGPAPGGPAQPPPTPQPSMADLQFSQLLG 606
            G   PP PA +    G             T  P P G + PP  P P+  +        
Sbjct: 765 AGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKE-------- 816

Query: 607 NLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQ 666
              G  GP  G  G    T  V   G P F        +A    PP  P P     AP  
Sbjct: 817 ---GLRGP-RGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGI 872

Query: 667 QTMP----PPGSP--SGGAGSPGGLGL 687
             +P      G P  +G  G PG LG+
Sbjct: 873 LGLPGSRGERGLPGVAGAVGEPGPLGI 899



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 100/353 (28%), Positives = 119/353 (33%), Gaps = 75/353 (21%)

Query: 375  VGTTVTMTGNGTRPPPTPNAEAPPPG----PGQASSVAPSSTNVESSAEGAPPPGPAPPP 430
            VG       NG   P     +  PPG    PG A    P   +  S   G  PPGPA   
Sbjct: 759  VGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPG--PPGPAGKE 816

Query: 431  ATSHPR-----VIRISHQ-SVEPVVMMHMN--IQDSGTQ-PGGVPSAPTGPLGPPG---- 477
                PR     V R     +V P           ++GT  P G P  P G LG PG    
Sbjct: 817  GLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPG-PQGLLGAPGILGL 875

Query: 478  HGQTLGQQVPGFPTA---PTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLA-- 532
             G    + +PG   A   P  + IA P   +  P   G P V+G    AG   N      
Sbjct: 876  PGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGP 935

Query: 533  ---------QMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPG 583
                     +   G  G +   PV  A G PG   P  PA    + G T  +   GPA  
Sbjct: 936  PGRDGQPGHKGERGYPGNI--GPVGAA-GAPGPHGPVGPAGKHGNRGETGPSGPVGPAGA 992

Query: 584  GPAQPPPTPQ-----------------------------PSMADLQFSQLLGNLLGPAGP 614
               + P  PQ                             P +A     Q     +GPAGP
Sbjct: 993  VGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGP 1052

Query: 615  --GAGGSGVASPTITVAMPGV--PAFLQGMTDFLQATQ-TAPPPPPPPPPPPP 662
               AG SG A        PG   PA ++G     Q  Q  A PP PP PP PP
Sbjct: 1053 RGPAGPSGPAGKDGRTGHPGTVGPAGIRGP----QGHQGPAGPPGPPGPPGPP 1101



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 89/321 (27%), Positives = 106/321 (33%), Gaps = 59/321 (18%)

Query: 474 GPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQ 533
           GP G     G++ P  P  P R     PT P   P  PG P + G       G    L  
Sbjct: 33  GPAGDRGPRGERGP--PGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP 90

Query: 534 MVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPA-----------P 582
              GL+G    +    A G PG      PA      G T  A   GPA           P
Sbjct: 91  GPMGLMGP---RGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHP 147

Query: 583 GGPAQP--------------PPTP-QPSMADLQFSQLLGNLLGPAG-------PGA-GGS 619
           G P +P              P TP  P    ++    L  L G  G       PGA G +
Sbjct: 148 GKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGEN 207

Query: 620 GVASPTITVAMPGV--------PAFLQGMTDFLQATQTAPP-----PPPPPPPPPPAPEQ 666
           G    T    +PG         PA  +G    +     A P     PP  P  P P  E 
Sbjct: 208 GTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEI 267

Query: 667 QTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQR 726
             +   G P+G AG  G +GL  LS         G      G  GA+  +     A    
Sbjct: 268 GAVGNAG-PAGPAGPRGEVGLPGLSGPVGPPGNPGA----NGLTGAKGAAGLPGVAGAPG 322

Query: 727 LSGSSNIFEPGADGALGFFGA 747
           L G   I  PG  GA G  GA
Sbjct: 323 LPGPRGI--PGPVGAAGATGA 341


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 88/326 (26%), Positives = 119/326 (36%), Gaps = 45/326 (13%)

Query: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIR----- 439
           G  P P P+   P PGP   + + PS      SA     P P PP A  HP   +     
Sbjct: 9   GGTPRPGPS---PGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA-GHPIPTQGPGGY 64

Query: 440 ---ISHQSVEPVVMMH----------MNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQV 486
                HQ  +P+  MH            ++  G + GG       P     H Q     +
Sbjct: 65  PQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPL 124

Query: 487 PGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQL---L 543
            G   A + V  + P+      S PGG P+ G    A    N          + QL   +
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 544 MQPVLVAQGTP----------GMAPPPAPATASASAGTTN-TATTAGPAPGGPAQPPPTP 592
           M   ++A+G P          G  P P       +    + +AT  GP PG    P P P
Sbjct: 185 MAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPG----PGPGP 240

Query: 593 QPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVP--AFLQG-MTDFLQATQT 649
            P  A   +S+  G + GP  P  G SGV  P +    PG P   + +G M +    T T
Sbjct: 241 GPGPAPPNYSRPHG-MGGPNMPPPGPSGV-PPGMPGQPPGGPPKPWPEGPMANAAAPTST 298

Query: 650 APPPPPPPPPPPPAPEQQTMPPPGSP 675
                PP P   P+P    +PP  SP
Sbjct: 299 PQKLIPPQPTGRPSPAPPAVPPAASP 324



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 56/209 (26%), Positives = 63/209 (30%), Gaps = 90/209 (43%)

Query: 386 TRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP-PPATSHPRVIRISHQS 444
           T PPP+ +A  P PGPG                   P PGP P PP  S P  +      
Sbjct: 219 TLPPPSVSATGPGPGPGPG-----------------PGPGPGPAPPNYSRPHGM------ 255

Query: 445 VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPP 504
                             GG    P GP G P          PG P  P           
Sbjct: 256 ------------------GGPNMPPPGPSGVP----------PGMPGQP----------- 276

Query: 505 QARPSHPGGPPV---SGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPA 561
                 PGGPP     G +  A   T+            Q L+ P     G P  APP  
Sbjct: 277 ------PGGPPKPWPEGPMANAAAPTSTP----------QKLIPPQ--PTGRPSPAPPAV 318

Query: 562 PATASASAGTTNTATTAGPAPGGPAQPPP 590
           P  AS              +PG PAQP P
Sbjct: 319 PPAASP------VMPPQTQSPGQPAQPAP 341



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 84/350 (24%), Positives = 116/350 (33%), Gaps = 58/350 (16%)

Query: 188 GPQP--QHSQPPPQP-PAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           GP P   HS   P P P     P+        P ++     +PME+  + E+  + +P  
Sbjct: 33  GPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMES--MHEKGMSDDPRY 90

Query: 245 TP---------GPAPAGPTPAP-ETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV 294
                      G A  GP P+P + ++  +PSP         L   E    P        
Sbjct: 91  NQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP---------LGGSEHASSPV-----PA 136

Query: 295 LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFV---ALSDLRCNLACTP------ 345
            G ++    ++   G   D      +G+  R  G T      L  LR  +          
Sbjct: 137 SGPSSGPQMSSGPGGAPLDGADPQALGQQNR--GPTPFNQNQLHQLRAQIMAYKMLARGQ 194

Query: 346 --PRHLHVV----RPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP-- 397
             P HL +     RPM     P + QQ       +V  T    G G  P P P    P  
Sbjct: 195 PLPDHLQMAVQGKRPM-----PGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 398 --PPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNI 455
             P G G  +   P  + V     G PP GP P P    P     +  S    ++     
Sbjct: 250 SRPHGMGGPNMPPPGPSGVPPGMPGQPPGGP-PKPWPEGPMANAAAPTSTPQKLIPPQPT 308

Query: 456 QDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQ 505
                 P  VP A   P+ PP   Q+ GQ     P  P     +R TP Q
Sbjct: 309 GRPSPAPPAVPPA-ASPVMPP-QTQSPGQPAQPAPMVPLHQKQSRITPIQ 356



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 39/128 (30%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 187 GGPQPQHSQPPPQPPAVTPE-PVA-LSSQTSEPVE----------SEAPPREPMEAEEVE 234
           G P     QPP  PP   PE P+A  ++ TS P +          S APP  P  A  V 
Sbjct: 267 GVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM 326

Query: 235 ERAPAQNPELTPGPAPAGPTPAPETNAP--NHPSPAEYVEVLQELQ-RLESRLQPFLQRY 291
                Q+P     PAP  P    ++       P   + VE+LQE + RL++R+   +Q  
Sbjct: 327 P-PQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQEL 385

Query: 292 YEVLGAAA 299
             + G+ A
Sbjct: 386 ENLPGSLA 393



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 67/282 (23%), Positives = 85/282 (30%), Gaps = 69/282 (24%)

Query: 420 GAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG 479
           G P PGP+P P  S   ++  S                 G  PG   S      GPP  G
Sbjct: 10  GTPRPGPSPGPGPSPGAMLGPS----------------PGPSPGSAHSMMGPSPGPPSAG 53

Query: 480 QTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLV 539
             +  Q PG         + +P            P  +   Q  G+G       M SG  
Sbjct: 54  HPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN---QMKGMG-------MRSG-- 101

Query: 540 GQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQ----PPPTPQPS 595
                       G  GM PPP+P    +            P+P G ++    P P   PS
Sbjct: 102 ------------GHAGMGPPPSPMDQHSQGY---------PSPLGGSEHASSPVPASGPS 140

Query: 596 MADLQFSQLLGNLLGPAGPGAGGSGVASPT-----------ITVAMPGVPAFLQGMTDFL 644
                 S   G  L  A P A G     PT             +    + A  Q + D L
Sbjct: 141 SGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHL 200

Query: 645 QATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686
           Q       P P      P     T+PPP   + G G   G G
Sbjct: 201 QMAVQGKRPMPGMQQQMP-----TLPPPSVSATGPGPGPGPG 237



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 52/222 (23%), Positives = 72/222 (32%), Gaps = 74/222 (33%)

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557
           ++ P PP      PG  P  G   GA LG                               
Sbjct: 1   MSTPDPPLGGTPRPGPSPGPGPSPGAMLG------------------------------- 29

Query: 558 PPPAPATASASAGTTNTATTAGPAPGGPA--QPPPT------PQPSM------------- 596
           P P P+  SA        +  GP+PG P+   P PT      PQ +M             
Sbjct: 30  PSPGPSPGSAH-------SMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEK 82

Query: 597 ---ADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPP 653
               D +++Q+ G  +G    G  G G     +     G P+ L G         +    
Sbjct: 83  GMSDDPRYNQMKG--MGMRSGGHAGMGPPPSPMDQHSQGYPSPLGG---------SEHAS 131

Query: 654 PPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFF 695
            P P   P +  Q +  P G+P  GA  P  LG ++  P  F
Sbjct: 132 SPVPASGPSSGPQMSSGPGGAPLDGA-DPQALGQQNRGPTPF 172



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 15/176 (8%)

Query: 942  QPLPEE-PMEVQGAERASPEPQREN--------ASPAPGTTAEEAMSRGPPPAPEGGSRD 992
            QPLP+   M VQG +R  P  Q++         ++  PG         GP PAP   SR 
Sbjct: 194  QPLPDHLQMAVQG-KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRP 252

Query: 993  EQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEG 1052
               G      P  + VPP    +  Q      K  P+ P+++A       ++    Q  G
Sbjct: 253  HGMGGPNMPPPGPSGVPP---GMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTG 309

Query: 1053 PQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDP 1108
                   AV  AA         SP   ++   AP V    +Q   + IQK    DP
Sbjct: 310  RPSPAPPAVPPAASPVMPPQTQSPGQPAQ--PAPMVPLHQKQSRITPIQKPRGLDP 363



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 15/99 (15%)

Query: 171 HMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEA 230
           H +R  Q +  +M  RG P P H Q            +A+  +   P   +  P  P  +
Sbjct: 178 HQLR-AQIMAYKMLARGQPLPDHLQ------------MAVQGKRPMPGMQQQMPTLPPPS 224

Query: 231 EEVEERAPAQNPELTPGPAPAGPTPAPE--TNAPNHPSP 267
                  P   P   PGP PA P  +       PN P P
Sbjct: 225 VSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPP 263



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 21/99 (21%)

Query: 938  GDPPQPLPEEPMEVQGAERASPE---PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQ 994
            G PP+P PE PM    A  ++P+   P +    P+P           PP  P   S    
Sbjct: 278  GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSP----------APPAVPPAASPVMP 327

Query: 995  DGASAETEPWAAAVPPEWVPIIQQD-----IQSQRKVKP 1028
                +  +P   A P   VP+ Q+      IQ  R + P
Sbjct: 328  PQTQSPGQP---AQPAPMVPLHQKQSRITPIQKPRGLDP 363


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 88/326 (26%), Positives = 119/326 (36%), Gaps = 45/326 (13%)

Query: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIR----- 439
           G  P P P+   P PGP   + + PS      SA     P P PP A  HP   +     
Sbjct: 9   GGTPRPGPS---PGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA-GHPIPTQGPGGY 64

Query: 440 ---ISHQSVEPVVMMH----------MNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQV 486
                HQ  +P+  MH            ++  G + GG       P     H Q     +
Sbjct: 65  PQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPL 124

Query: 487 PGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQL---L 543
            G   A + V  + P+      S PGG P+ G    A    N          + QL   +
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 544 MQPVLVAQGTP----------GMAPPPAPATASASAGTTN-TATTAGPAPGGPAQPPPTP 592
           M   ++A+G P          G  P P       +    + +AT  GP PG    P P P
Sbjct: 185 MAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPG----PGPGP 240

Query: 593 QPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVP--AFLQG-MTDFLQATQT 649
            P  A   +S+  G + GP  P  G SGV  P +    PG P   + +G M +    T T
Sbjct: 241 GPGPAPPNYSRPHG-MGGPNMPPPGPSGV-PPGMPGQPPGGPPKPWPEGPMANAAAPTST 298

Query: 650 APPPPPPPPPPPPAPEQQTMPPPGSP 675
                PP P   P+P    +PP  SP
Sbjct: 299 PQKLIPPQPTGRPSPAPPAVPPAASP 324



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 56/209 (26%), Positives = 63/209 (30%), Gaps = 90/209 (43%)

Query: 386 TRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP-PPATSHPRVIRISHQS 444
           T PPP+ +A  P PGPG                   P PGP P PP  S P  +      
Sbjct: 219 TLPPPSVSATGPGPGPGPG-----------------PGPGPGPAPPNYSRPHGM------ 255

Query: 445 VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPP 504
                             GG    P GP G P          PG P  P           
Sbjct: 256 ------------------GGPNMPPPGPSGVP----------PGMPGQP----------- 276

Query: 505 QARPSHPGGPPV---SGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPA 561
                 PGGPP     G +  A   T+            Q L+ P     G P  APP  
Sbjct: 277 ------PGGPPKPWPEGPMANAAAPTSTP----------QKLIPPQ--PTGRPSPAPPAV 318

Query: 562 PATASASAGTTNTATTAGPAPGGPAQPPP 590
           P  AS              +PG PAQP P
Sbjct: 319 PPAASP------VMPPQTQSPGQPAQPAP 341



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 84/350 (24%), Positives = 116/350 (33%), Gaps = 58/350 (16%)

Query: 188 GPQP--QHSQPPPQP-PAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           GP P   HS   P P P     P+        P ++     +PME+  + E+  + +P  
Sbjct: 33  GPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMES--MHEKGMSDDPRY 90

Query: 245 TP---------GPAPAGPTPAP-ETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV 294
                      G A  GP P+P + ++  +PSP         L   E    P        
Sbjct: 91  NQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP---------LGGSEHASSPV-----PA 136

Query: 295 LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFV---ALSDLRCNLACTP------ 345
            G ++    ++   G   D      +G+  R  G T      L  LR  +          
Sbjct: 137 SGPSSGPQMSSGPGGAPLDGADPQALGQQNR--GPTPFNQNQLHQLRAQIMAYKMLARGQ 194

Query: 346 --PRHLHVV----RPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP-- 397
             P HL +     RPM     P + QQ       +V  T    G G  P P P    P  
Sbjct: 195 PLPDHLQMAVQGKRPM-----PGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 398 --PPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNI 455
             P G G  +   P  + V     G PP GP P P    P     +  S    ++     
Sbjct: 250 SRPHGMGGPNMPPPGPSGVPPGMPGQPPGGP-PKPWPEGPMANAAAPTSTPQKLIPPQPT 308

Query: 456 QDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQ 505
                 P  VP A   P+ PP   Q+ GQ     P  P     +R TP Q
Sbjct: 309 GRPSPAPPAVPPA-ASPVMPP-QTQSPGQPAQPAPMVPLHQKQSRITPIQ 356



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 39/128 (30%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 187 GGPQPQHSQPPPQPPAVTPE-PVA-LSSQTSEPVE----------SEAPPREPMEAEEVE 234
           G P     QPP  PP   PE P+A  ++ TS P +          S APP  P  A  V 
Sbjct: 267 GVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM 326

Query: 235 ERAPAQNPELTPGPAPAGPTPAPETNAP--NHPSPAEYVEVLQELQ-RLESRLQPFLQRY 291
                Q+P     PAP  P    ++       P   + VE+LQE + RL++R+   +Q  
Sbjct: 327 P-PQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQEL 385

Query: 292 YEVLGAAA 299
             + G+ A
Sbjct: 386 ENLPGSLA 393



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 67/282 (23%), Positives = 85/282 (30%), Gaps = 69/282 (24%)

Query: 420 GAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG 479
           G P PGP+P P  S   ++  S                 G  PG   S      GPP  G
Sbjct: 10  GTPRPGPSPGPGPSPGAMLGPS----------------PGPSPGSAHSMMGPSPGPPSAG 53

Query: 480 QTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLV 539
             +  Q PG         + +P            P  +   Q  G+G       M SG  
Sbjct: 54  HPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN---QMKGMG-------MRSG-- 101

Query: 540 GQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQ----PPPTPQPS 595
                       G  GM PPP+P    +            P+P G ++    P P   PS
Sbjct: 102 ------------GHAGMGPPPSPMDQHSQGY---------PSPLGGSEHASSPVPASGPS 140

Query: 596 MADLQFSQLLGNLLGPAGPGAGGSGVASPT-----------ITVAMPGVPAFLQGMTDFL 644
                 S   G  L  A P A G     PT             +    + A  Q + D L
Sbjct: 141 SGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHL 200

Query: 645 QATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686
           Q       P P      P     T+PPP   + G G   G G
Sbjct: 201 QMAVQGKRPMPGMQQQMP-----TLPPPSVSATGPGPGPGPG 237



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 52/222 (23%), Positives = 72/222 (32%), Gaps = 74/222 (33%)

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557
           ++ P PP      PG  P  G   GA LG                               
Sbjct: 1   MSTPDPPLGGTPRPGPSPGPGPSPGAMLG------------------------------- 29

Query: 558 PPPAPATASASAGTTNTATTAGPAPGGPA--QPPPT------PQPSM------------- 596
           P P P+  SA        +  GP+PG P+   P PT      PQ +M             
Sbjct: 30  PSPGPSPGSAH-------SMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEK 82

Query: 597 ---ADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPP 653
               D +++Q+ G  +G    G  G G     +     G P+ L G         +    
Sbjct: 83  GMSDDPRYNQMKG--MGMRSGGHAGMGPPPSPMDQHSQGYPSPLGG---------SEHAS 131

Query: 654 PPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFF 695
            P P   P +  Q +  P G+P  GA  P  LG ++  P  F
Sbjct: 132 SPVPASGPSSGPQMSSGPGGAPLDGA-DPQALGQQNRGPTPF 172



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 15/176 (8%)

Query: 942  QPLPEE-PMEVQGAERASPEPQREN--------ASPAPGTTAEEAMSRGPPPAPEGGSRD 992
            QPLP+   M VQG +R  P  Q++         ++  PG         GP PAP   SR 
Sbjct: 194  QPLPDHLQMAVQG-KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRP 252

Query: 993  EQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEG 1052
               G      P  + VPP    +  Q      K  P+ P+++A       ++    Q  G
Sbjct: 253  HGMGGPNMPPPGPSGVPP---GMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTG 309

Query: 1053 PQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDP 1108
                   AV  AA         SP   ++   AP V    +Q   + IQK    DP
Sbjct: 310  RPSPAPPAVPPAASPVMPPQTQSPGQPAQ--PAPMVPLHQKQSRITPIQKPRGLDP 363



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 15/99 (15%)

Query: 171 HMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEA 230
           H +R  Q +  +M  RG P P H Q            +A+  +   P   +  P  P  +
Sbjct: 178 HQLR-AQIMAYKMLARGQPLPDHLQ------------MAVQGKRPMPGMQQQMPTLPPPS 224

Query: 231 EEVEERAPAQNPELTPGPAPAGPTPAPE--TNAPNHPSP 267
                  P   P   PGP PA P  +       PN P P
Sbjct: 225 VSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPP 263



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 21/99 (21%)

Query: 938  GDPPQPLPEEPMEVQGAERASPE---PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQ 994
            G PP+P PE PM    A  ++P+   P +    P+P           PP  P   S    
Sbjct: 278  GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSP----------APPAVPPAASPVMP 327

Query: 995  DGASAETEPWAAAVPPEWVPIIQQD-----IQSQRKVKP 1028
                +  +P   A P   VP+ Q+      IQ  R + P
Sbjct: 328  PQTQSPGQP---AQPAPMVPLHQKQSRITPIQKPRGLDP 363


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 88/326 (26%), Positives = 119/326 (36%), Gaps = 45/326 (13%)

Query: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIR----- 439
           G  P P P+   P PGP   + + PS      SA     P P PP A  HP   +     
Sbjct: 9   GGTPRPGPS---PGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA-GHPIPTQGPGGY 64

Query: 440 ---ISHQSVEPVVMMH----------MNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQV 486
                HQ  +P+  MH            ++  G + GG       P     H Q     +
Sbjct: 65  PQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPL 124

Query: 487 PGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQL---L 543
            G   A + V  + P+      S PGG P+ G    A    N          + QL   +
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 544 MQPVLVAQGTP----------GMAPPPAPATASASAGTTN-TATTAGPAPGGPAQPPPTP 592
           M   ++A+G P          G  P P       +    + +AT  GP PG    P P P
Sbjct: 185 MAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPG----PGPGP 240

Query: 593 QPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVP--AFLQG-MTDFLQATQT 649
            P  A   +S+  G + GP  P  G SGV  P +    PG P   + +G M +    T T
Sbjct: 241 GPGPAPPNYSRPHG-MGGPNMPPPGPSGV-PPGMPGQPPGGPPKPWPEGPMANAAAPTST 298

Query: 650 APPPPPPPPPPPPAPEQQTMPPPGSP 675
                PP P   P+P    +PP  SP
Sbjct: 299 PQKLIPPQPTGRPSPAPPAVPPAASP 324



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 56/209 (26%), Positives = 63/209 (30%), Gaps = 90/209 (43%)

Query: 386 TRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP-PPATSHPRVIRISHQS 444
           T PPP+ +A  P PGPG                   P PGP P PP  S P  +      
Sbjct: 219 TLPPPSVSATGPGPGPGPG-----------------PGPGPGPAPPNYSRPHGM------ 255

Query: 445 VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPP 504
                             GG    P GP G P          PG P  P           
Sbjct: 256 ------------------GGPNMPPPGPSGVP----------PGMPGQP----------- 276

Query: 505 QARPSHPGGPPV---SGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPA 561
                 PGGPP     G +  A   T+            Q L+ P     G P  APP  
Sbjct: 277 ------PGGPPKPWPEGPMANAAAPTSTP----------QKLIPPQ--PTGRPSPAPPAV 318

Query: 562 PATASASAGTTNTATTAGPAPGGPAQPPP 590
           P  AS              +PG PAQP P
Sbjct: 319 PPAASP------VMPPQTQSPGQPAQPAP 341



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 84/350 (24%), Positives = 116/350 (33%), Gaps = 58/350 (16%)

Query: 188 GPQP--QHSQPPPQP-PAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           GP P   HS   P P P     P+        P ++     +PME+  + E+  + +P  
Sbjct: 33  GPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMES--MHEKGMSDDPRY 90

Query: 245 TP---------GPAPAGPTPAP-ETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV 294
                      G A  GP P+P + ++  +PSP         L   E    P        
Sbjct: 91  NQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP---------LGGSEHASSPV-----PA 136

Query: 295 LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFV---ALSDLRCNLACTP------ 345
            G ++    ++   G   D      +G+  R  G T      L  LR  +          
Sbjct: 137 SGPSSGPQMSSGPGGAPLDGADPQALGQQNR--GPTPFNQNQLHQLRAQIMAYKMLARGQ 194

Query: 346 --PRHLHVV----RPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP-- 397
             P HL +     RPM     P + QQ       +V  T    G G  P P P    P  
Sbjct: 195 PLPDHLQMAVQGKRPM-----PGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 398 --PPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNI 455
             P G G  +   P  + V     G PP GP P P    P     +  S    ++     
Sbjct: 250 SRPHGMGGPNMPPPGPSGVPPGMPGQPPGGP-PKPWPEGPMANAAAPTSTPQKLIPPQPT 308

Query: 456 QDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQ 505
                 P  VP A   P+ PP   Q+ GQ     P  P     +R TP Q
Sbjct: 309 GRPSPAPPAVPPA-ASPVMPP-QTQSPGQPAQPAPMVPLHQKQSRITPIQ 356



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 39/128 (30%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 187 GGPQPQHSQPPPQPPAVTPE-PVA-LSSQTSEPVE----------SEAPPREPMEAEEVE 234
           G P     QPP  PP   PE P+A  ++ TS P +          S APP  P  A  V 
Sbjct: 267 GVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM 326

Query: 235 ERAPAQNPELTPGPAPAGPTPAPETNAP--NHPSPAEYVEVLQELQ-RLESRLQPFLQRY 291
                Q+P     PAP  P    ++       P   + VE+LQE + RL++R+   +Q  
Sbjct: 327 P-PQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQEL 385

Query: 292 YEVLGAAA 299
             + G+ A
Sbjct: 386 ENLPGSLA 393



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 67/282 (23%), Positives = 85/282 (30%), Gaps = 69/282 (24%)

Query: 420 GAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG 479
           G P PGP+P P  S   ++  S                 G  PG   S      GPP  G
Sbjct: 10  GTPRPGPSPGPGPSPGAMLGPS----------------PGPSPGSAHSMMGPSPGPPSAG 53

Query: 480 QTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLV 539
             +  Q PG         + +P            P  +   Q  G+G       M SG  
Sbjct: 54  HPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN---QMKGMG-------MRSG-- 101

Query: 540 GQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQ----PPPTPQPS 595
                       G  GM PPP+P    +            P+P G ++    P P   PS
Sbjct: 102 ------------GHAGMGPPPSPMDQHSQGY---------PSPLGGSEHASSPVPASGPS 140

Query: 596 MADLQFSQLLGNLLGPAGPGAGGSGVASPT-----------ITVAMPGVPAFLQGMTDFL 644
                 S   G  L  A P A G     PT             +    + A  Q + D L
Sbjct: 141 SGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHL 200

Query: 645 QATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686
           Q       P P      P     T+PPP   + G G   G G
Sbjct: 201 QMAVQGKRPMPGMQQQMP-----TLPPPSVSATGPGPGPGPG 237



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 52/222 (23%), Positives = 72/222 (32%), Gaps = 74/222 (33%)

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557
           ++ P PP      PG  P  G   GA LG                               
Sbjct: 1   MSTPDPPLGGTPRPGPSPGPGPSPGAMLG------------------------------- 29

Query: 558 PPPAPATASASAGTTNTATTAGPAPGGPA--QPPPT------PQPSM------------- 596
           P P P+  SA        +  GP+PG P+   P PT      PQ +M             
Sbjct: 30  PSPGPSPGSAH-------SMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEK 82

Query: 597 ---ADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPP 653
               D +++Q+ G  +G    G  G G     +     G P+ L G         +    
Sbjct: 83  GMSDDPRYNQMKG--MGMRSGGHAGMGPPPSPMDQHSQGYPSPLGG---------SEHAS 131

Query: 654 PPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFF 695
            P P   P +  Q +  P G+P  GA  P  LG ++  P  F
Sbjct: 132 SPVPASGPSSGPQMSSGPGGAPLDGA-DPQALGQQNRGPTPF 172



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 15/176 (8%)

Query: 942  QPLPEE-PMEVQGAERASPEPQREN--------ASPAPGTTAEEAMSRGPPPAPEGGSRD 992
            QPLP+   M VQG +R  P  Q++         ++  PG         GP PAP   SR 
Sbjct: 194  QPLPDHLQMAVQG-KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRP 252

Query: 993  EQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEG 1052
               G      P  + VPP    +  Q      K  P+ P+++A       ++    Q  G
Sbjct: 253  HGMGGPNMPPPGPSGVPP---GMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTG 309

Query: 1053 PQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDP 1108
                   AV  AA         SP   ++   AP V    +Q   + IQK    DP
Sbjct: 310  RPSPAPPAVPPAASPVMPPQTQSPGQPAQ--PAPMVPLHQKQSRITPIQKPRGLDP 363



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 15/99 (15%)

Query: 171 HMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEA 230
           H +R  Q +  +M  RG P P H Q            +A+  +   P   +  P  P  +
Sbjct: 178 HQLR-AQIMAYKMLARGQPLPDHLQ------------MAVQGKRPMPGMQQQMPTLPPPS 224

Query: 231 EEVEERAPAQNPELTPGPAPAGPTPAPE--TNAPNHPSP 267
                  P   P   PGP PA P  +       PN P P
Sbjct: 225 VSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPP 263



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 21/99 (21%)

Query: 938  GDPPQPLPEEPMEVQGAERASPE---PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQ 994
            G PP+P PE PM    A  ++P+   P +    P+P           PP  P   S    
Sbjct: 278  GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSP----------APPAVPPAASPVMP 327

Query: 995  DGASAETEPWAAAVPPEWVPIIQQD-----IQSQRKVKP 1028
                +  +P   A P   VP+ Q+      IQ  R + P
Sbjct: 328  PQTQSPGQP---AQPAPMVPLHQKQSRITPIQKPRGLDP 363


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 88/326 (26%), Positives = 119/326 (36%), Gaps = 45/326 (13%)

Query: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIR----- 439
           G  P P P+   P PGP   + + PS      SA     P P PP A  HP   +     
Sbjct: 9   GGTPRPGPS---PGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA-GHPIPTQGPGGY 64

Query: 440 ---ISHQSVEPVVMMH----------MNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQV 486
                HQ  +P+  MH            ++  G + GG       P     H Q     +
Sbjct: 65  PQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPL 124

Query: 487 PGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQL---L 543
            G   A + V  + P+      S PGG P+ G    A    N          + QL   +
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 544 MQPVLVAQGTP----------GMAPPPAPATASASAGTTN-TATTAGPAPGGPAQPPPTP 592
           M   ++A+G P          G  P P       +    + +AT  GP PG    P P P
Sbjct: 185 MAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPG----PGPGP 240

Query: 593 QPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVP--AFLQG-MTDFLQATQT 649
            P  A   +S+  G + GP  P  G SGV  P +    PG P   + +G M +    T T
Sbjct: 241 GPGPAPPNYSRPHG-MGGPNMPPPGPSGV-PPGMPGQPPGGPPKPWPEGPMANAAAPTST 298

Query: 650 APPPPPPPPPPPPAPEQQTMPPPGSP 675
                PP P   P+P    +PP  SP
Sbjct: 299 PQKLIPPQPTGRPSPAPPAVPPAASP 324



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 56/209 (26%), Positives = 63/209 (30%), Gaps = 90/209 (43%)

Query: 386 TRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP-PPATSHPRVIRISHQS 444
           T PPP+ +A  P PGPG                   P PGP P PP  S P  +      
Sbjct: 219 TLPPPSVSATGPGPGPGPG-----------------PGPGPGPAPPNYSRPHGM------ 255

Query: 445 VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPP 504
                             GG    P GP G P          PG P  P           
Sbjct: 256 ------------------GGPNMPPPGPSGVP----------PGMPGQP----------- 276

Query: 505 QARPSHPGGPPV---SGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPA 561
                 PGGPP     G +  A   T+            Q L+ P     G P  APP  
Sbjct: 277 ------PGGPPKPWPEGPMANAAAPTSTP----------QKLIPPQ--PTGRPSPAPPAV 318

Query: 562 PATASASAGTTNTATTAGPAPGGPAQPPP 590
           P  AS              +PG PAQP P
Sbjct: 319 PPAASP------VMPPQTQSPGQPAQPAP 341



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 84/350 (24%), Positives = 116/350 (33%), Gaps = 58/350 (16%)

Query: 188 GPQP--QHSQPPPQP-PAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           GP P   HS   P P P     P+        P ++     +PME+  + E+  + +P  
Sbjct: 33  GPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMES--MHEKGMSDDPRY 90

Query: 245 TP---------GPAPAGPTPAP-ETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV 294
                      G A  GP P+P + ++  +PSP         L   E    P        
Sbjct: 91  NQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP---------LGGSEHASSPV-----PA 136

Query: 295 LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFV---ALSDLRCNLACTP------ 345
            G ++    ++   G   D      +G+  R  G T      L  LR  +          
Sbjct: 137 SGPSSGPQMSSGPGGAPLDGADPQALGQQNR--GPTPFNQNQLHQLRAQIMAYKMLARGQ 194

Query: 346 --PRHLHVV----RPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP-- 397
             P HL +     RPM     P + QQ       +V  T    G G  P P P    P  
Sbjct: 195 PLPDHLQMAVQGKRPM-----PGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 398 --PPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNI 455
             P G G  +   P  + V     G PP GP P P    P     +  S    ++     
Sbjct: 250 SRPHGMGGPNMPPPGPSGVPPGMPGQPPGGP-PKPWPEGPMANAAAPTSTPQKLIPPQPT 308

Query: 456 QDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQ 505
                 P  VP A   P+ PP   Q+ GQ     P  P     +R TP Q
Sbjct: 309 GRPSPAPPAVPPA-ASPVMPP-QTQSPGQPAQPAPMVPLHQKQSRITPIQ 356



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 39/128 (30%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 187 GGPQPQHSQPPPQPPAVTPE-PVA-LSSQTSEPVE----------SEAPPREPMEAEEVE 234
           G P     QPP  PP   PE P+A  ++ TS P +          S APP  P  A  V 
Sbjct: 267 GVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM 326

Query: 235 ERAPAQNPELTPGPAPAGPTPAPETNAP--NHPSPAEYVEVLQELQ-RLESRLQPFLQRY 291
                Q+P     PAP  P    ++       P   + VE+LQE + RL++R+   +Q  
Sbjct: 327 P-PQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQEL 385

Query: 292 YEVLGAAA 299
             + G+ A
Sbjct: 386 ENLPGSLA 393



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 67/282 (23%), Positives = 85/282 (30%), Gaps = 69/282 (24%)

Query: 420 GAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG 479
           G P PGP+P P  S   ++  S                 G  PG   S      GPP  G
Sbjct: 10  GTPRPGPSPGPGPSPGAMLGPS----------------PGPSPGSAHSMMGPSPGPPSAG 53

Query: 480 QTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLV 539
             +  Q PG         + +P            P  +   Q  G+G       M SG  
Sbjct: 54  HPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN---QMKGMG-------MRSG-- 101

Query: 540 GQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQ----PPPTPQPS 595
                       G  GM PPP+P    +            P+P G ++    P P   PS
Sbjct: 102 ------------GHAGMGPPPSPMDQHSQGY---------PSPLGGSEHASSPVPASGPS 140

Query: 596 MADLQFSQLLGNLLGPAGPGAGGSGVASPT-----------ITVAMPGVPAFLQGMTDFL 644
                 S   G  L  A P A G     PT             +    + A  Q + D L
Sbjct: 141 SGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHL 200

Query: 645 QATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686
           Q       P P      P     T+PPP   + G G   G G
Sbjct: 201 QMAVQGKRPMPGMQQQMP-----TLPPPSVSATGPGPGPGPG 237



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 52/222 (23%), Positives = 72/222 (32%), Gaps = 74/222 (33%)

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557
           ++ P PP      PG  P  G   GA LG                               
Sbjct: 1   MSTPDPPLGGTPRPGPSPGPGPSPGAMLG------------------------------- 29

Query: 558 PPPAPATASASAGTTNTATTAGPAPGGPA--QPPPT------PQPSM------------- 596
           P P P+  SA        +  GP+PG P+   P PT      PQ +M             
Sbjct: 30  PSPGPSPGSAH-------SMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEK 82

Query: 597 ---ADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPP 653
               D +++Q+ G  +G    G  G G     +     G P+ L G         +    
Sbjct: 83  GMSDDPRYNQMKG--MGMRSGGHAGMGPPPSPMDQHSQGYPSPLGG---------SEHAS 131

Query: 654 PPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFF 695
            P P   P +  Q +  P G+P  GA  P  LG ++  P  F
Sbjct: 132 SPVPASGPSSGPQMSSGPGGAPLDGA-DPQALGQQNRGPTPF 172



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 15/176 (8%)

Query: 942  QPLPEE-PMEVQGAERASPEPQREN--------ASPAPGTTAEEAMSRGPPPAPEGGSRD 992
            QPLP+   M VQG +R  P  Q++         ++  PG         GP PAP   SR 
Sbjct: 194  QPLPDHLQMAVQG-KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRP 252

Query: 993  EQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEG 1052
               G      P  + VPP    +  Q      K  P+ P+++A       ++    Q  G
Sbjct: 253  HGMGGPNMPPPGPSGVPP---GMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTG 309

Query: 1053 PQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDP 1108
                   AV  AA         SP   ++   AP V    +Q   + IQK    DP
Sbjct: 310  RPSPAPPAVPPAASPVMPPQTQSPGQPAQ--PAPMVPLHQKQSRITPIQKPRGLDP 363



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 15/99 (15%)

Query: 171 HMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEA 230
           H +R  Q +  +M  RG P P H Q            +A+  +   P   +  P  P  +
Sbjct: 178 HQLR-AQIMAYKMLARGQPLPDHLQ------------MAVQGKRPMPGMQQQMPTLPPPS 224

Query: 231 EEVEERAPAQNPELTPGPAPAGPTPAPE--TNAPNHPSP 267
                  P   P   PGP PA P  +       PN P P
Sbjct: 225 VSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPP 263



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 21/99 (21%)

Query: 938  GDPPQPLPEEPMEVQGAERASPE---PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQ 994
            G PP+P PE PM    A  ++P+   P +    P+P           PP  P   S    
Sbjct: 278  GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSP----------APPAVPPAASPVMP 327

Query: 995  DGASAETEPWAAAVPPEWVPIIQQD-----IQSQRKVKP 1028
                +  +P   A P   VP+ Q+      IQ  R + P
Sbjct: 328  PQTQSPGQP---AQPAPMVPLHQKQSRITPIQKPRGLDP 363


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 88/326 (26%), Positives = 119/326 (36%), Gaps = 45/326 (13%)

Query: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIR----- 439
           G  P P P+   P PGP   + + PS      SA     P P PP A  HP   +     
Sbjct: 9   GGTPRPGPS---PGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA-GHPIPTQGPGGY 64

Query: 440 ---ISHQSVEPVVMMH----------MNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQV 486
                HQ  +P+  MH            ++  G + GG       P     H Q     +
Sbjct: 65  PQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPL 124

Query: 487 PGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQL---L 543
            G   A + V  + P+      S PGG P+ G    A    N          + QL   +
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 544 MQPVLVAQGTP----------GMAPPPAPATASASAGTTN-TATTAGPAPGGPAQPPPTP 592
           M   ++A+G P          G  P P       +    + +AT  GP PG    P P P
Sbjct: 185 MAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPG----PGPGP 240

Query: 593 QPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVP--AFLQG-MTDFLQATQT 649
            P  A   +S+  G + GP  P  G SGV  P +    PG P   + +G M +    T T
Sbjct: 241 GPGPAPPNYSRPHG-MGGPNMPPPGPSGV-PPGMPGQPPGGPPKPWPEGPMANAAAPTST 298

Query: 650 APPPPPPPPPPPPAPEQQTMPPPGSP 675
                PP P   P+P    +PP  SP
Sbjct: 299 PQKLIPPQPTGRPSPAPPAVPPAASP 324



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 56/209 (26%), Positives = 63/209 (30%), Gaps = 90/209 (43%)

Query: 386 TRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP-PPATSHPRVIRISHQS 444
           T PPP+ +A  P PGPG                   P PGP P PP  S P  +      
Sbjct: 219 TLPPPSVSATGPGPGPGPG-----------------PGPGPGPAPPNYSRPHGM------ 255

Query: 445 VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPP 504
                             GG    P GP G P          PG P  P           
Sbjct: 256 ------------------GGPNMPPPGPSGVP----------PGMPGQP----------- 276

Query: 505 QARPSHPGGPPV---SGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPA 561
                 PGGPP     G +  A   T+            Q L+ P     G P  APP  
Sbjct: 277 ------PGGPPKPWPEGPMANAAAPTSTP----------QKLIPPQ--PTGRPSPAPPAV 318

Query: 562 PATASASAGTTNTATTAGPAPGGPAQPPP 590
           P  AS              +PG PAQP P
Sbjct: 319 PPAASP------VMPPQTQSPGQPAQPAP 341



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 84/350 (24%), Positives = 116/350 (33%), Gaps = 58/350 (16%)

Query: 188 GPQP--QHSQPPPQP-PAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           GP P   HS   P P P     P+        P ++     +PME+  + E+  + +P  
Sbjct: 33  GPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMES--MHEKGMSDDPRY 90

Query: 245 TP---------GPAPAGPTPAP-ETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV 294
                      G A  GP P+P + ++  +PSP         L   E    P        
Sbjct: 91  NQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP---------LGGSEHASSPV-----PA 136

Query: 295 LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFV---ALSDLRCNLACTP------ 345
            G ++    ++   G   D      +G+  R  G T      L  LR  +          
Sbjct: 137 SGPSSGPQMSSGPGGAPLDGADPQALGQQNR--GPTPFNQNQLHQLRAQIMAYKMLARGQ 194

Query: 346 --PRHLHVV----RPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP-- 397
             P HL +     RPM     P + QQ       +V  T    G G  P P P    P  
Sbjct: 195 PLPDHLQMAVQGKRPM-----PGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 398 --PPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNI 455
             P G G  +   P  + V     G PP GP P P    P     +  S    ++     
Sbjct: 250 SRPHGMGGPNMPPPGPSGVPPGMPGQPPGGP-PKPWPEGPMANAAAPTSTPQKLIPPQPT 308

Query: 456 QDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQ 505
                 P  VP A   P+ PP   Q+ GQ     P  P     +R TP Q
Sbjct: 309 GRPSPAPPAVPPA-ASPVMPP-QTQSPGQPAQPAPMVPLHQKQSRITPIQ 356



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 39/128 (30%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 187 GGPQPQHSQPPPQPPAVTPE-PVA-LSSQTSEPVE----------SEAPPREPMEAEEVE 234
           G P     QPP  PP   PE P+A  ++ TS P +          S APP  P  A  V 
Sbjct: 267 GVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM 326

Query: 235 ERAPAQNPELTPGPAPAGPTPAPETNAP--NHPSPAEYVEVLQELQ-RLESRLQPFLQRY 291
                Q+P     PAP  P    ++       P   + VE+LQE + RL++R+   +Q  
Sbjct: 327 P-PQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQEL 385

Query: 292 YEVLGAAA 299
             + G+ A
Sbjct: 386 ENLPGSLA 393



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 67/282 (23%), Positives = 85/282 (30%), Gaps = 69/282 (24%)

Query: 420 GAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG 479
           G P PGP+P P  S   ++  S                 G  PG   S      GPP  G
Sbjct: 10  GTPRPGPSPGPGPSPGAMLGPS----------------PGPSPGSAHSMMGPSPGPPSAG 53

Query: 480 QTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLV 539
             +  Q PG         + +P            P  +   Q  G+G       M SG  
Sbjct: 54  HPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN---QMKGMG-------MRSG-- 101

Query: 540 GQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQ----PPPTPQPS 595
                       G  GM PPP+P    +            P+P G ++    P P   PS
Sbjct: 102 ------------GHAGMGPPPSPMDQHSQGY---------PSPLGGSEHASSPVPASGPS 140

Query: 596 MADLQFSQLLGNLLGPAGPGAGGSGVASPT-----------ITVAMPGVPAFLQGMTDFL 644
                 S   G  L  A P A G     PT             +    + A  Q + D L
Sbjct: 141 SGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHL 200

Query: 645 QATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686
           Q       P P      P     T+PPP   + G G   G G
Sbjct: 201 QMAVQGKRPMPGMQQQMP-----TLPPPSVSATGPGPGPGPG 237



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 52/222 (23%), Positives = 72/222 (32%), Gaps = 74/222 (33%)

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557
           ++ P PP      PG  P  G   GA LG                               
Sbjct: 1   MSTPDPPLGGTPRPGPSPGPGPSPGAMLG------------------------------- 29

Query: 558 PPPAPATASASAGTTNTATTAGPAPGGPA--QPPPT------PQPSM------------- 596
           P P P+  SA        +  GP+PG P+   P PT      PQ +M             
Sbjct: 30  PSPGPSPGSAH-------SMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEK 82

Query: 597 ---ADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPP 653
               D +++Q+ G  +G    G  G G     +     G P+ L G         +    
Sbjct: 83  GMSDDPRYNQMKG--MGMRSGGHAGMGPPPSPMDQHSQGYPSPLGG---------SEHAS 131

Query: 654 PPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFF 695
            P P   P +  Q +  P G+P  GA  P  LG ++  P  F
Sbjct: 132 SPVPASGPSSGPQMSSGPGGAPLDGA-DPQALGQQNRGPTPF 172



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 15/176 (8%)

Query: 942  QPLPEE-PMEVQGAERASPEPQREN--------ASPAPGTTAEEAMSRGPPPAPEGGSRD 992
            QPLP+   M VQG +R  P  Q++         ++  PG         GP PAP   SR 
Sbjct: 194  QPLPDHLQMAVQG-KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRP 252

Query: 993  EQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEG 1052
               G      P  + VPP    +  Q      K  P+ P+++A       ++    Q  G
Sbjct: 253  HGMGGPNMPPPGPSGVPP---GMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTG 309

Query: 1053 PQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDP 1108
                   AV  AA         SP   ++   AP V    +Q   + IQK    DP
Sbjct: 310  RPSPAPPAVPPAASPVMPPQTQSPGQPAQ--PAPMVPLHQKQSRITPIQKPRGLDP 363



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 15/99 (15%)

Query: 171 HMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEA 230
           H +R  Q +  +M  RG P P H Q            +A+  +   P   +  P  P  +
Sbjct: 178 HQLR-AQIMAYKMLARGQPLPDHLQ------------MAVQGKRPMPGMQQQMPTLPPPS 224

Query: 231 EEVEERAPAQNPELTPGPAPAGPTPAPE--TNAPNHPSP 267
                  P   P   PGP PA P  +       PN P P
Sbjct: 225 VSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPP 263



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 21/99 (21%)

Query: 938  GDPPQPLPEEPMEVQGAERASPE---PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQ 994
            G PP+P PE PM    A  ++P+   P +    P+P           PP  P   S    
Sbjct: 278  GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSP----------APPAVPPAASPVMP 327

Query: 995  DGASAETEPWAAAVPPEWVPIIQQD-----IQSQRKVKP 1028
                +  +P   A P   VP+ Q+      IQ  R + P
Sbjct: 328  PQTQSPGQP---AQPAPMVPLHQKQSRITPIQKPRGLDP 363


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
           regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 88/326 (26%), Positives = 119/326 (36%), Gaps = 45/326 (13%)

Query: 385 GTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIR----- 439
           G  P P P+   P PGP   + + PS      SA     P P PP A  HP   +     
Sbjct: 9   GGTPRPGPS---PGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSA-GHPIPTQGPGGY 64

Query: 440 ---ISHQSVEPVVMMH----------MNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQV 486
                HQ  +P+  MH            ++  G + GG       P     H Q     +
Sbjct: 65  PQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSPL 124

Query: 487 PGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQL---L 543
            G   A + V  + P+      S PGG P+ G    A    N          + QL   +
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184

Query: 544 MQPVLVAQGTP----------GMAPPPAPATASASAGTTN-TATTAGPAPGGPAQPPPTP 592
           M   ++A+G P          G  P P       +    + +AT  GP PG    P P P
Sbjct: 185 MAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPG----PGPGP 240

Query: 593 QPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVP--AFLQG-MTDFLQATQT 649
            P  A   +S+  G + GP  P  G SGV  P +    PG P   + +G M +    T T
Sbjct: 241 GPGPAPPNYSRPHG-MGGPNMPPPGPSGV-PPGMPGQPPGGPPKPWPEGPMANAAAPTST 298

Query: 650 APPPPPPPPPPPPAPEQQTMPPPGSP 675
                PP P   P+P    +PP  SP
Sbjct: 299 PQKLIPPQPTGRPSPAPPAVPPAASP 324



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 56/209 (26%), Positives = 63/209 (30%), Gaps = 90/209 (43%)

Query: 386 TRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAP-PPATSHPRVIRISHQS 444
           T PPP+ +A  P PGPG                   P PGP P PP  S P  +      
Sbjct: 219 TLPPPSVSATGPGPGPGPG-----------------PGPGPGPAPPNYSRPHGM------ 255

Query: 445 VEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPP 504
                             GG    P GP G P          PG P  P           
Sbjct: 256 ------------------GGPNMPPPGPSGVP----------PGMPGQP----------- 276

Query: 505 QARPSHPGGPPV---SGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPA 561
                 PGGPP     G +  A   T+            Q L+ P     G P  APP  
Sbjct: 277 ------PGGPPKPWPEGPMANAAAPTSTP----------QKLIPPQ--PTGRPSPAPPAV 318

Query: 562 PATASASAGTTNTATTAGPAPGGPAQPPP 590
           P  AS              +PG PAQP P
Sbjct: 319 PPAASP------VMPPQTQSPGQPAQPAP 341



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 84/350 (24%), Positives = 116/350 (33%), Gaps = 58/350 (16%)

Query: 188 GPQP--QHSQPPPQP-PAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNPEL 244
           GP P   HS   P P P     P+        P ++     +PME+  + E+  + +P  
Sbjct: 33  GPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMES--MHEKGMSDDPRY 90

Query: 245 TP---------GPAPAGPTPAP-ETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV 294
                      G A  GP P+P + ++  +PSP         L   E    P        
Sbjct: 91  NQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP---------LGGSEHASSPV-----PA 136

Query: 295 LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFV---ALSDLRCNLACTP------ 345
            G ++    ++   G   D      +G+  R  G T      L  LR  +          
Sbjct: 137 SGPSSGPQMSSGPGGAPLDGADPQALGQQNR--GPTPFNQNQLHQLRAQIMAYKMLARGQ 194

Query: 346 --PRHLHVV----RPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAP-- 397
             P HL +     RPM     P + QQ       +V  T    G G  P P P    P  
Sbjct: 195 PLPDHLQMAVQGKRPM-----PGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNY 249

Query: 398 --PPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNI 455
             P G G  +   P  + V     G PP GP P P    P     +  S    ++     
Sbjct: 250 SRPHGMGGPNMPPPGPSGVPPGMPGQPPGGP-PKPWPEGPMANAAAPTSTPQKLIPPQPT 308

Query: 456 QDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQ 505
                 P  VP A   P+ PP   Q+ GQ     P  P     +R TP Q
Sbjct: 309 GRPSPAPPAVPPA-ASPVMPP-QTQSPGQPAQPAPMVPLHQKQSRITPIQ 356



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 39/128 (30%), Positives = 55/128 (42%), Gaps = 16/128 (12%)

Query: 187 GGPQPQHSQPPPQPPAVTPE-PVA-LSSQTSEPVE----------SEAPPREPMEAEEVE 234
           G P     QPP  PP   PE P+A  ++ TS P +          S APP  P  A  V 
Sbjct: 267 GVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASPVM 326

Query: 235 ERAPAQNPELTPGPAPAGPTPAPETNAP--NHPSPAEYVEVLQELQ-RLESRLQPFLQRY 291
                Q+P     PAP  P    ++       P   + VE+LQE + RL++R+   +Q  
Sbjct: 327 P-PQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRGLDPVEILQEREYRLQARIAHRIQEL 385

Query: 292 YEVLGAAA 299
             + G+ A
Sbjct: 386 ENLPGSLA 393



 Score = 35.8 bits (81), Expect = 0.23
 Identities = 67/282 (23%), Positives = 85/282 (30%), Gaps = 69/282 (24%)

Query: 420 GAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHG 479
           G P PGP+P P  S   ++  S                 G  PG   S      GPP  G
Sbjct: 10  GTPRPGPSPGPGPSPGAMLGPS----------------PGPSPGSAHSMMGPSPGPPSAG 53

Query: 480 QTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLV 539
             +  Q PG         + +P            P  +   Q  G+G       M SG  
Sbjct: 54  HPIPTQGPGGYPQDNMHQMHKPMESMHEKGMSDDPRYN---QMKGMG-------MRSG-- 101

Query: 540 GQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQ----PPPTPQPS 595
                       G  GM PPP+P    +            P+P G ++    P P   PS
Sbjct: 102 ------------GHAGMGPPPSPMDQHSQGY---------PSPLGGSEHASSPVPASGPS 140

Query: 596 MADLQFSQLLGNLLGPAGPGAGGSGVASPT-----------ITVAMPGVPAFLQGMTDFL 644
                 S   G  L  A P A G     PT             +    + A  Q + D L
Sbjct: 141 SGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAYKMLARGQPLPDHL 200

Query: 645 QATQTAPPPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLG 686
           Q       P P      P     T+PPP   + G G   G G
Sbjct: 201 QMAVQGKRPMPGMQQQMP-----TLPPPSVSATGPGPGPGPG 237



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 52/222 (23%), Positives = 72/222 (32%), Gaps = 74/222 (33%)

Query: 498 IARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMA 557
           ++ P PP      PG  P  G   GA LG                               
Sbjct: 1   MSTPDPPLGGTPRPGPSPGPGPSPGAMLG------------------------------- 29

Query: 558 PPPAPATASASAGTTNTATTAGPAPGGPA--QPPPT------PQPSM------------- 596
           P P P+  SA        +  GP+PG P+   P PT      PQ +M             
Sbjct: 30  PSPGPSPGSAH-------SMMGPSPGPPSAGHPIPTQGPGGYPQDNMHQMHKPMESMHEK 82

Query: 597 ---ADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPP 653
               D +++Q+ G  +G    G  G G     +     G P+ L G         +    
Sbjct: 83  GMSDDPRYNQMKG--MGMRSGGHAGMGPPPSPMDQHSQGYPSPLGG---------SEHAS 131

Query: 654 PPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFF 695
            P P   P +  Q +  P G+P  GA  P  LG ++  P  F
Sbjct: 132 SPVPASGPSSGPQMSSGPGGAPLDGA-DPQALGQQNRGPTPF 172



 Score = 32.0 bits (71), Expect = 3.4
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 15/176 (8%)

Query: 942  QPLPEE-PMEVQGAERASPEPQREN--------ASPAPGTTAEEAMSRGPPPAPEGGSRD 992
            QPLP+   M VQG +R  P  Q++         ++  PG         GP PAP   SR 
Sbjct: 194  QPLPDHLQMAVQG-KRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRP 252

Query: 993  EQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEG 1052
               G      P  + VPP    +  Q      K  P+ P+++A       ++    Q  G
Sbjct: 253  HGMGGPNMPPPGPSGVPP---GMPGQPPGGPPKPWPEGPMANAAAPTSTPQKLIPPQPTG 309

Query: 1053 PQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDP 1108
                   AV  AA         SP   ++   AP V    +Q   + IQK    DP
Sbjct: 310  RPSPAPPAVPPAASPVMPPQTQSPGQPAQ--PAPMVPLHQKQSRITPIQKPRGLDP 363



 Score = 31.6 bits (70), Expect = 4.4
 Identities = 26/99 (26%), Positives = 35/99 (35%), Gaps = 15/99 (15%)

Query: 171 HMIRDIQTLLSRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEA 230
           H +R  Q +  +M  RG P P H Q            +A+  +   P   +  P  P  +
Sbjct: 178 HQLR-AQIMAYKMLARGQPLPDHLQ------------MAVQGKRPMPGMQQQMPTLPPPS 224

Query: 231 EEVEERAPAQNPELTPGPAPAGPTPAPE--TNAPNHPSP 267
                  P   P   PGP PA P  +       PN P P
Sbjct: 225 VSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPP 263



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 27/99 (27%), Positives = 38/99 (38%), Gaps = 21/99 (21%)

Query: 938  GDPPQPLPEEPMEVQGAERASPE---PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQ 994
            G PP+P PE PM    A  ++P+   P +    P+P           PP  P   S    
Sbjct: 278  GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSP----------APPAVPPAASPVMP 327

Query: 995  DGASAETEPWAAAVPPEWVPIIQQD-----IQSQRKVKP 1028
                +  +P   A P   VP+ Q+      IQ  R + P
Sbjct: 328  PQTQSPGQP---AQPAPMVPLHQKQSRITPIQKPRGLDP 363


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.131    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,288,515
Number of Sequences: 37866
Number of extensions: 4500348
Number of successful extensions: 104723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1153
Number of HSP's successfully gapped in prelim test: 1983
Number of HSP's that attempted gapping in prelim test: 31158
Number of HSP's gapped (non-prelim): 39737
length of query: 1126
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1013
effective length of database: 13,968,660
effective search space: 14150252580
effective search space used: 14150252580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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