Guide to the Human Genome
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Search of human proteins with 148839378

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo
sapiens]
         (294 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]    613   e-176
gi|22779877 connexin 46 [Homo sapiens]                                208   5e-54
gi|55953076 connexin 50 [Homo sapiens]                                198   5e-51
gi|62865885 connexin 37 [Homo sapiens]                                187   1e-47
gi|32483412 connexin 40 [Homo sapiens]                                182   2e-46
gi|6631083 connexin 40 [Homo sapiens]                                 182   2e-46
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]       180   2e-45
gi|14211941 gap junction protein, alpha 10 [Homo sapiens]             177   1e-44
gi|122939172 connexin 45 [Homo sapiens]                               173   1e-43
gi|69122473 connexin 45 [Homo sapiens]                                173   1e-43
gi|4504001 connexin 43 [Homo sapiens]                                 171   5e-43
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]       154   9e-38
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]         154   9e-38
gi|145699105 connexin40.1 [Homo sapiens]                              153   2e-37
gi|42558283 gap junction protein beta 2 [Homo sapiens]                149   3e-36
gi|23397464 gap junction protein, beta 4 [Homo sapiens]               149   4e-36
gi|159032020 gap junction protein, beta 6 [Homo sapiens]              147   1e-35
gi|158966714 gap junction protein, beta 6 [Homo sapiens]              147   1e-35
gi|158966717 gap junction protein, beta 6 [Homo sapiens]              147   1e-35
gi|40254837 gap junction protein, beta 6 [Homo sapiens]               147   1e-35
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]        137   9e-33
gi|54607056 connexin 31 [Homo sapiens]                                135   4e-32
gi|13128960 connexin 31 [Homo sapiens]                                135   4e-32
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]       130   1e-30
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]      129   2e-30
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]     129   4e-30
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]       111   7e-25
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]           87   2e-17
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]           87   2e-17
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]           87   2e-17

>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
          Length = 294

 Score =  613 bits (1581), Expect = e-176
 Identities = 294/294 (100%), Positives = 294/294 (100%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG
Sbjct: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEA 120
           CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEA
Sbjct: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEA 120

Query: 121 QCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCF 180
           QCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCF
Sbjct: 121 QCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCF 180

Query: 181 VSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGERDNRCNRAHEEAQKLLPP 240
           VSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGERDNRCNRAHEEAQKLLPP
Sbjct: 181 VSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGERDNRCNRAHEEAQKLLPP 240

Query: 241 PPPPPPPPALPSRRPGPEPCAPPAYAHPAPASLRECGSGRGKASPATGRRDLAI 294
           PPPPPPPPALPSRRPGPEPCAPPAYAHPAPASLRECGSGRGKASPATGRRDLAI
Sbjct: 241 PPPPPPPPALPSRRPGPEPCAPPAYAHPAPASLRECGSGRGKASPATGRRDLAI 294


>gi|22779877 connexin 46 [Homo sapiens]
          Length = 435

 Score =  208 bits (529), Expect = 5e-54
 Identities = 120/308 (38%), Positives = 162/308 (52%), Gaps = 20/308 (6%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MG+W+FLG LL+  Q  S ++G++WL V+ IFRILVL      V+ DEQ +F CNT QPG
Sbjct: 1   MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMH-----RAGKEAGGAEAAAQCAP 115
           C   CYDRAFP+SH RFW   I+ +S P ++++ + +H        KE    E   + +P
Sbjct: 61  CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP 120

Query: 116 GLPEAQCAPCALRARRAR--------RCYLLSVALRLLAELTFLGGQALLYGFRVAPHFA 167
              E      + R  R R        R Y+ ++  + L E+ F+ GQ  LYGF + P + 
Sbjct: 121 SPKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYR 180

Query: 168 CAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGERDNRC 227
           C   PCP+TVDCF+SRPTEKT+F++F  AV   S LL++ E+ HL WK + + G      
Sbjct: 181 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWK-KLKQGVTSRLG 239

Query: 228 NRAHEEAQKLLPPPPPPPPPPALPSRRPGPEPCAPPAYAH-PAPASLRECGSGRGKASPA 286
             A E       PPP PP      SR P      PP YAH  AP          G   PA
Sbjct: 240 PDASEAPLGTADPPPLPP-----SSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPA 294

Query: 287 TGRRDLAI 294
              + LA+
Sbjct: 295 ADFKLLAL 302


>gi|55953076 connexin 50 [Homo sapiens]
          Length = 433

 Score =  198 bits (503), Expect = 5e-51
 Identities = 98/231 (42%), Positives = 141/231 (61%), Gaps = 15/231 (6%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MG+W+FLG++L+ V   S ++GR+WL V+ IFRIL+L T    V+ DEQ +FVCNT QPG
Sbjct: 1   MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMH-------RAGKEAG--GAEAAA 111
           C   CYD AFP+SH R W+  I+ +S P +++V +++H       R  +EA   G +A  
Sbjct: 61  CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120

Query: 112 QCAPGLPEAQCAPCALRARRAR------RCYLLSVALRLLAELTFLGGQALLYGFRVAPH 165
              P     + +  +   ++ R      R Y+  +  + L E+ F+ G   LYGFR+ P 
Sbjct: 121 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL 180

Query: 166 FACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKG 216
           + C+  PCP+ VDCFVSRPTEKT+F+LF  +V  +S  L+V ELGHL  KG
Sbjct: 181 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKG 231


>gi|62865885 connexin 37 [Homo sapiens]
          Length = 333

 Score =  187 bits (475), Expect = 1e-47
 Identities = 97/232 (41%), Positives = 136/232 (58%), Gaps = 19/232 (8%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MG+W FL  LLD VQ  S +VG++WL V+ IFRIL+L   G +V+ DEQ +F CNT QPG
Sbjct: 1   MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFV--VYSMHRAGKEAGGAEAAAQCAPGL- 117
           C   CYD+AFP+SH R+W+   L +S P ++++  V  + R  +     E   +  P   
Sbjct: 61  CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKD 120

Query: 118 PEAQCAPCALRARRAR----------------RCYLLSVALRLLAELTFLGGQALLYGFR 161
           P+ + A  A+  + A+                  Y+ SV  + + E  FL GQ  LYG+ 
Sbjct: 121 PQVERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWT 180

Query: 162 VAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLL 213
           + P F C   PCP+ VDCFVSRPTEKT+F++F   VGL+S +L++ EL HLL
Sbjct: 181 MEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLL 232


>gi|32483412 connexin 40 [Homo sapiens]
          Length = 358

 Score =  182 bits (463), Expect = 2e-46
 Identities = 93/233 (39%), Positives = 135/233 (57%), Gaps = 19/233 (8%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MG+W+FLG+ L+ V   S +VG++WL V+ IFR+LVL T   + + DEQ +F C+T+QPG
Sbjct: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMH-------------RAGKEAGGA 107
           C+  CYD+AFP+SH R+W+  I+ +S P ++++ ++MH                KE  G+
Sbjct: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120

Query: 108 EAAAQCAPGLPEAQC-----APCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRV 162
            +         E  C        AL+       Y+ S+ +R   E+ F+ GQ  +YG  +
Sbjct: 121 GSYEYPVAEKAELSCWEEGNGRIALQG-TLLNTYVCSILIRTTMEVGFIVGQYFIYGIFL 179

Query: 163 APHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215
                C   PCPH V+C+VSRPTEK VF++F  AV  LS LLS+AEL HL WK
Sbjct: 180 TTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWK 232


>gi|6631083 connexin 40 [Homo sapiens]
          Length = 358

 Score =  182 bits (463), Expect = 2e-46
 Identities = 93/233 (39%), Positives = 135/233 (57%), Gaps = 19/233 (8%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MG+W+FLG+ L+ V   S +VG++WL V+ IFR+LVL T   + + DEQ +F C+T+QPG
Sbjct: 1   MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMH-------------RAGKEAGGA 107
           C+  CYD+AFP+SH R+W+  I+ +S P ++++ ++MH                KE  G+
Sbjct: 61  CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS 120

Query: 108 EAAAQCAPGLPEAQC-----APCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRV 162
            +         E  C        AL+       Y+ S+ +R   E+ F+ GQ  +YG  +
Sbjct: 121 GSYEYPVAEKAELSCWEEGNGRIALQG-TLLNTYVCSILIRTTMEVGFIVGQYFIYGIFL 179

Query: 163 APHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215
                C   PCPH V+C+VSRPTEK VF++F  AV  LS LLS+AEL HL WK
Sbjct: 180 TTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWK 232


>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
          Length = 515

 Score =  180 bits (456), Expect = 2e-45
 Identities = 91/254 (35%), Positives = 142/254 (55%), Gaps = 21/254 (8%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MG+W  LG  L+ V + S ++G++WL ++ IFR+LVL      V+ DEQ  F+CNT QPG
Sbjct: 1   MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAG-KEAGGAEAAAQCAPGLPE 119
           CR  CYD+AFP+S  R+W+  ++ +S+P ++++ ++++R    E       AQ    L E
Sbjct: 61  CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120

Query: 120 AQCAP-----------CALRARRARRC---------YLLSVALRLLAELTFLGGQALLYG 159
            +              C L  R+  +          Y++ +  R + E+ F+ GQ LLYG
Sbjct: 121 VEFEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYG 180

Query: 160 FRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPR 219
           F + P F C G PCP+ +DCFVSRPTEKT+F+LF  ++  +S  L++ E+ HL +K   R
Sbjct: 181 FHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIKR 240

Query: 220 AGERDNRCNRAHEE 233
                 +  + H E
Sbjct: 241 GLWGKYKLKKEHNE 254


>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
          Length = 543

 Score =  177 bits (449), Expect = 1e-44
 Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 21/233 (9%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MG+W  LG +L+ V   S +VG++WL ++ IFR+LVL      V++DEQ  F CNT QPG
Sbjct: 1   MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHR-----AGKEAGGAEAAAQCAP 115
           C   CYD AFP+S  RFW+  I+ +S+P ++++ ++++R       ++   +   AQ   
Sbjct: 61  CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120

Query: 116 ---GLPEAQCAPCALRARRAR-------------RCYLLSVALRLLAELTFLGGQALLYG 159
               L E Q     LR    +             R Y+L +  R + E+ F+ GQ +LYG
Sbjct: 121 PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG 180

Query: 160 FRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHL 212
           F++ P + C  PPCP+ VDCFVSRPTEKT+F+LF  ++  +S LL++ E+ HL
Sbjct: 181 FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHL 233


>gi|122939172 connexin 45 [Homo sapiens]
          Length = 396

 Score =  173 bits (439), Expect = 1e-43
 Identities = 93/252 (36%), Positives = 137/252 (54%), Gaps = 44/252 (17%)

Query: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
           W+FL  LL+ +   S  VG++WL V+++FRI++ A  G +++ DEQ +FVCNT QPGC  
Sbjct: 3   WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62

Query: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLP----- 118
            CYD   P+SH RFW+F I+L++ P V+++ Y++H+  K   G EA  + A   P     
Sbjct: 63  VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHG-EADKKAARSKPYAMRW 121

Query: 119 ---------------------------------EAQCAPCALRARRAR-----RCYLLSV 140
                                            ++Q  P     RR R     + Y+L +
Sbjct: 122 KQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQL 181

Query: 141 ALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLL 200
             R + E+ FL GQ  LYGF+V P + C+  PCPH +DCF+SRPTEKT+F+L  + V  L
Sbjct: 182 LARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGL 241

Query: 201 SALLSVAELGHL 212
             LL++ E+ HL
Sbjct: 242 CLLLNIWEMLHL 253


>gi|69122473 connexin 45 [Homo sapiens]
          Length = 396

 Score =  173 bits (439), Expect = 1e-43
 Identities = 93/252 (36%), Positives = 137/252 (54%), Gaps = 44/252 (17%)

Query: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
           W+FL  LL+ +   S  VG++WL V+++FRI++ A  G +++ DEQ +FVCNT QPGC  
Sbjct: 3   WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62

Query: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLP----- 118
            CYD   P+SH RFW+F I+L++ P V+++ Y++H+  K   G EA  + A   P     
Sbjct: 63  VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHG-EADKKAARSKPYAMRW 121

Query: 119 ---------------------------------EAQCAPCALRARRAR-----RCYLLSV 140
                                            ++Q  P     RR R     + Y+L +
Sbjct: 122 KQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQL 181

Query: 141 ALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLL 200
             R + E+ FL GQ  LYGF+V P + C+  PCPH +DCF+SRPTEKT+F+L  + V  L
Sbjct: 182 LARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGL 241

Query: 201 SALLSVAELGHL 212
             LL++ E+ HL
Sbjct: 242 CLLLNIWEMLHL 253


>gi|4504001 connexin 43 [Homo sapiens]
          Length = 382

 Score =  171 bits (434), Expect = 5e-43
 Identities = 86/235 (36%), Positives = 130/235 (55%), Gaps = 19/235 (8%)

Query: 1   MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
           MG+W+ LG LLD VQ  S   G++WL V+ IFRIL+L T   + + DEQ  F CNT QPG
Sbjct: 1   MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG 60

Query: 61  CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEA 120
           C   CYD++FP+SH RFW+  I+ +S P +L++ +  +   KE    +   +      + 
Sbjct: 61  CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG 120

Query: 121 QCAPCALRARRAR-------------------RCYLLSVALRLLAELTFLGGQALLYGFR 161
                 L+    +                   R Y++S+  + + E+ FL  Q  +YGF 
Sbjct: 121 VNVDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFS 180

Query: 162 VAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKG 216
           ++  + C   PCPH VDCF+SRPTEKT+F++F   V L+S  L++ EL ++ +KG
Sbjct: 181 LSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKG 235


>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  154 bits (389), Expect = 9e-38
 Identities = 86/221 (38%), Positives = 120/221 (54%), Gaps = 1/221 (0%)

Query: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
           W  L +LL  V   S  +GR+WL V+ IFRI+VL     +V+ DE+  F+CNTLQPGC  
Sbjct: 3   WTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNS 62

Query: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCA 123
            CYD+ FP+SH R W   ++L+S P +L  ++  H+   E           P   E    
Sbjct: 63  VCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKR 122

Query: 124 PCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVDCFVS 182
                +      Y++SV  RLL E  F+    LLY G+ +     C   PCP+TVDCFVS
Sbjct: 123 HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVS 182

Query: 183 RPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGER 223
           RPTEKTVF +F  A   +  +L+VAE+ +L+ +   R  +R
Sbjct: 183 RPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQR 223


>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
          Length = 283

 Score =  154 bits (389), Expect = 9e-38
 Identities = 86/221 (38%), Positives = 120/221 (54%), Gaps = 1/221 (0%)

Query: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
           W  L +LL  V   S  +GR+WL V+ IFRI+VL     +V+ DE+  F+CNTLQPGC  
Sbjct: 3   WTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNS 62

Query: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCA 123
            CYD+ FP+SH R W   ++L+S P +L  ++  H+   E           P   E    
Sbjct: 63  VCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKR 122

Query: 124 PCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVDCFVS 182
                +      Y++SV  RLL E  F+    LLY G+ +     C   PCP+TVDCFVS
Sbjct: 123 HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVS 182

Query: 183 RPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGER 223
           RPTEKTVF +F  A   +  +L+VAE+ +L+ +   R  +R
Sbjct: 183 RPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQR 223


>gi|145699105 connexin40.1 [Homo sapiens]
          Length = 370

 Score =  153 bits (386), Expect = 2e-37
 Identities = 88/221 (39%), Positives = 115/221 (52%), Gaps = 29/221 (13%)

Query: 7   LGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCY 66
           LG L+  +     +VG+LW V+ ++ R+LV+   G  V++DEQE FVCNTLQPGC   CY
Sbjct: 7   LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66

Query: 67  DRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCAPCA 126
           D   PVSH RFWL   + +  P  +F VY +HR      GA  AA     L   +C    
Sbjct: 67  DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHR------GATLAA-----LGPRRCPDPR 115

Query: 127 LRARRARRC------------------YLLSVALRLLAELTFLGGQALLYGFRVAPHFAC 168
             A   RRC                  Y++ + LR L E  F      L+GF     F C
Sbjct: 116 EPASGQRRCPRPFGERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPC 175

Query: 169 AGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAEL 209
             PPC   VDC+VSRPTEK++ +LF +AV  LS LL +A+L
Sbjct: 176 TRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADL 216


>gi|42558283 gap junction protein beta 2 [Homo sapiens]
          Length = 226

 Score =  149 bits (376), Expect = 3e-36
 Identities = 82/215 (38%), Positives = 118/215 (54%), Gaps = 6/215 (2%)

Query: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62
           +W  L ++L  V   S  +G++WL V+ IFRI++L      V+ DEQ +FVCNTLQPGC+
Sbjct: 2   DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCK 61

Query: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVLF---VVYSMHRAGKEAGGAEAAAQCAPGLPE 119
             CYD  FP+SH R W   ++ +S P +L    V Y  H   ++    E  ++    + E
Sbjct: 62  NVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKD-IEE 120

Query: 120 AQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVD 178
            +     +        Y  S+  R++ E  F+    ++Y GF +     C   PCP+TVD
Sbjct: 121 IKTQKVRIEGS-LWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVD 179

Query: 179 CFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLL 213
           CFVSRPTEKTVF +F  AV  +  LL+V EL +LL
Sbjct: 180 CFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLL 214


>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
          Length = 266

 Score =  149 bits (375), Expect = 4e-36
 Identities = 84/215 (39%), Positives = 117/215 (54%), Gaps = 9/215 (4%)

Query: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
           WAFL  LL  V   S ++ R+WL V+ IFR+LV       V++DEQ++FVCNT QPGC  
Sbjct: 3   WAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPN 62

Query: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCA 123
            CYD  FPVSH R W   ++L++ P +L V++  +R  +E          AP L +    
Sbjct: 63  VCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYD---- 118

Query: 124 PCALRARRARR--CYLLSVALRLLAELTFLGGQALLYGFRVAPH-FACAGPPCPHTVDCF 180
              L  +R      YLLS+  +   +  FL     LY     P   AC+  PCPHTVDC+
Sbjct: 119 --NLSKKRGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCY 176

Query: 181 VSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215
           +SRPTEK VF  F      +  LL+++E+ +L+ K
Sbjct: 177 ISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGK 211


>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  147 bits (371), Expect = 1e-35
 Identities = 83/242 (34%), Positives = 128/242 (52%), Gaps = 10/242 (4%)

Query: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62
           +W  L + +  V   S  +G++W+ V+ IFR+++L      V+ DEQE+FVCNTLQPGC+
Sbjct: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61

Query: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVL---FVVYSMHRAGKEAGGAEAAAQCAPGLPE 119
             CYD  FPVSH R W   ++ +S P +L    V Y  H   ++    E        + +
Sbjct: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRND-FKDIED 120

Query: 120 AQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVD 178
            +     +        Y  S+  R++ E  F+     LY G+ +     C   PCP+ VD
Sbjct: 121 IKKQKVRIEG-SLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVD 179

Query: 179 CFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLL----WKGRPRAGERDNRCNRAHEEA 234
           CF+SRPTEKTVF +F  +  ++  LL+VAEL +LL    ++   RA  + N  N A +E+
Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKES 239

Query: 235 QK 236
           ++
Sbjct: 240 KQ 241


>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  147 bits (371), Expect = 1e-35
 Identities = 83/242 (34%), Positives = 128/242 (52%), Gaps = 10/242 (4%)

Query: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62
           +W  L + +  V   S  +G++W+ V+ IFR+++L      V+ DEQE+FVCNTLQPGC+
Sbjct: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61

Query: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVL---FVVYSMHRAGKEAGGAEAAAQCAPGLPE 119
             CYD  FPVSH R W   ++ +S P +L    V Y  H   ++    E        + +
Sbjct: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRND-FKDIED 120

Query: 120 AQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVD 178
            +     +        Y  S+  R++ E  F+     LY G+ +     C   PCP+ VD
Sbjct: 121 IKKQKVRIEG-SLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVD 179

Query: 179 CFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLL----WKGRPRAGERDNRCNRAHEEA 234
           CF+SRPTEKTVF +F  +  ++  LL+VAEL +LL    ++   RA  + N  N A +E+
Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKES 239

Query: 235 QK 236
           ++
Sbjct: 240 KQ 241


>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  147 bits (371), Expect = 1e-35
 Identities = 83/242 (34%), Positives = 128/242 (52%), Gaps = 10/242 (4%)

Query: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62
           +W  L + +  V   S  +G++W+ V+ IFR+++L      V+ DEQE+FVCNTLQPGC+
Sbjct: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61

Query: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVL---FVVYSMHRAGKEAGGAEAAAQCAPGLPE 119
             CYD  FPVSH R W   ++ +S P +L    V Y  H   ++    E        + +
Sbjct: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRND-FKDIED 120

Query: 120 AQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVD 178
            +     +        Y  S+  R++ E  F+     LY G+ +     C   PCP+ VD
Sbjct: 121 IKKQKVRIEG-SLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVD 179

Query: 179 CFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLL----WKGRPRAGERDNRCNRAHEEA 234
           CF+SRPTEKTVF +F  +  ++  LL+VAEL +LL    ++   RA  + N  N A +E+
Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKES 239

Query: 235 QK 236
           ++
Sbjct: 240 KQ 241


>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
          Length = 261

 Score =  147 bits (371), Expect = 1e-35
 Identities = 83/242 (34%), Positives = 128/242 (52%), Gaps = 10/242 (4%)

Query: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62
           +W  L + +  V   S  +G++W+ V+ IFR+++L      V+ DEQE+FVCNTLQPGC+
Sbjct: 2   DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61

Query: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVL---FVVYSMHRAGKEAGGAEAAAQCAPGLPE 119
             CYD  FPVSH R W   ++ +S P +L    V Y  H   ++    E        + +
Sbjct: 62  NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRND-FKDIED 120

Query: 120 AQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVD 178
            +     +        Y  S+  R++ E  F+     LY G+ +     C   PCP+ VD
Sbjct: 121 IKKQKVRIEG-SLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVD 179

Query: 179 CFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLL----WKGRPRAGERDNRCNRAHEEA 234
           CF+SRPTEKTVF +F  +  ++  LL+VAEL +LL    ++   RA  + N  N A +E+
Sbjct: 180 CFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHPNHALKES 239

Query: 235 QK 236
           ++
Sbjct: 240 KQ 241


>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
          Length = 223

 Score =  137 bits (346), Expect = 9e-33
 Identities = 77/213 (36%), Positives = 113/213 (53%), Gaps = 12/213 (5%)

Query: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
           W FL  LL  V   S   G +WL V+ +FR+LV       V++DEQ+EF CN+ QPGC+ 
Sbjct: 3   WMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKN 62

Query: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCA 123
            C+D  FP+S  R W   ++++S P +L V++  +  G+E    +     +PG  +    
Sbjct: 63  VCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKRHRK-KLYVSPGTMDG--- 118

Query: 124 PCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVDCFVS 182
                       YL+S+ ++   E+ FL     LY GF V     C   PCP+TVDCF+S
Sbjct: 119 -------GLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVDCFIS 171

Query: 183 RPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215
           +PTEKT+F+LF      L  +L+  EL  L+ K
Sbjct: 172 KPTEKTIFILFLVITSCLCIVLNFIELSFLVLK 204


>gi|54607056 connexin 31 [Homo sapiens]
          Length = 270

 Score =  135 bits (340), Expect = 4e-32
 Identities = 84/262 (32%), Positives = 127/262 (48%), Gaps = 31/262 (11%)

Query: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62
           +W  L +LL  V   S   GR+WL V+ +FR+LV       V+ DEQ++F CNT QPGC 
Sbjct: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61

Query: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQC 122
             CYD  FP+S+ R W   ++ ++ P +L +++  +R  +E    +            QC
Sbjct: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGD--------QC 113

Query: 123 APCALRARRARR----CYLLSVALRLLAELTFLG-GQALLYGFRVAPHFACAG-PPCPHT 176
           A     A +        YL S+  +L+ E  FL     L +GF +     CA   PCP+ 
Sbjct: 114 AKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173

Query: 177 VDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHL--------LWKGRPRAG------- 221
           VDC+++RPTEK +F  F      +  +L++ EL +L        L K +PR G       
Sbjct: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSA 233

Query: 222 ERDNRCNRAHE--EAQKLLPPP 241
            R + C   H+  EA ++ P P
Sbjct: 234 SRASTCRCHHKLVEAGEVDPDP 255


>gi|13128960 connexin 31 [Homo sapiens]
          Length = 270

 Score =  135 bits (340), Expect = 4e-32
 Identities = 84/262 (32%), Positives = 127/262 (48%), Gaps = 31/262 (11%)

Query: 3   EWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCR 62
           +W  L +LL  V   S   GR+WL V+ +FR+LV       V+ DEQ++F CNT QPGC 
Sbjct: 2   DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61

Query: 63  QTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQC 122
             CYD  FP+S+ R W   ++ ++ P +L +++  +R  +E    +            QC
Sbjct: 62  NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGD--------QC 113

Query: 123 APCALRARRARR----CYLLSVALRLLAELTFLG-GQALLYGFRVAPHFACAG-PPCPHT 176
           A     A +        YL S+  +L+ E  FL     L +GF +     CA   PCP+ 
Sbjct: 114 AKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173

Query: 177 VDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHL--------LWKGRPRAG------- 221
           VDC+++RPTEK +F  F      +  +L++ EL +L        L K +PR G       
Sbjct: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSA 233

Query: 222 ERDNRCNRAHE--EAQKLLPPP 241
            R + C   H+  EA ++ P P
Sbjct: 234 SRASTCRCHHKLVEAGEVDPDP 255


>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
          Length = 321

 Score =  130 bits (328), Expect = 1e-30
 Identities = 57/104 (54%), Positives = 79/104 (75%), Gaps = 1/104 (0%)

Query: 1   MGEWAFLGSLLDA-VQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQP 59
           MGEW  L  LL+A VQ  S ++GR+ L V++IFRIL++A VG  V++DEQ  FVCNTLQP
Sbjct: 1   MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60

Query: 60  GCRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKE 103
           GC Q CYDRAFP+SH R+W+F I+++  P + F+ YS+H++ K+
Sbjct: 61  GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQSAKQ 104



 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 40/82 (48%), Positives = 53/82 (64%)

Query: 134 RCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLF 193
           R Y++ V  R   E+ FL GQ  LYGF V   + C   PC   V+C+VSRPTEKTVF++F
Sbjct: 197 RFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVF 256

Query: 194 YFAVGLLSALLSVAELGHLLWK 215
            FAV  +  +L++AEL HL W+
Sbjct: 257 MFAVSGICVVLNLAELNHLGWR 278


>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
          Length = 273

 Score =  129 bits (325), Expect = 2e-30
 Identities = 72/217 (33%), Positives = 111/217 (51%), Gaps = 13/217 (5%)

Query: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
           W+    LL  V   S   GR+WL ++ IFR+LV       V+ D+ ++F CNT QPGC  
Sbjct: 3   WSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSN 62

Query: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCA 123
            C+D  FPVSH R W   ++L++ P +L V++  +R  +E    EA  + +  L      
Sbjct: 63  VCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKRHREAHGENSGRL------ 116

Query: 124 PCALRARRARR----CYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVD 178
              L   + R      Y+ S+  +   ++ FL      Y  + + P   C   PCP+ VD
Sbjct: 117 --YLNPGKKRGGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVD 174

Query: 179 CFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWK 215
           CF+S+P+EK +F LF  A   +  LL++ EL +L+ K
Sbjct: 175 CFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSK 211


>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
          Length = 279

 Score =  129 bits (323), Expect = 4e-30
 Identities = 86/252 (34%), Positives = 127/252 (50%), Gaps = 25/252 (9%)

Query: 6   FLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTC 65
           FL  LL     +S  VGRL L V+L FR+++LA  G  V+ DEQ EFVC+T QPGC+  C
Sbjct: 5   FLRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAAC 64

Query: 66  YDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRA---------GKEAGGAEAAAQCAPG 116
           +D   P+S  RFW+F ++L++ P  L++ ++++           GKE    E   Q   G
Sbjct: 65  FDAFHPLSPLRFWVFQVILVAVPSALYMGFTLYHVIWHWELSGKGKE---EETLIQGREG 121

Query: 117 LPEAQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRVAPHFACAGPPCPHT 176
             +   A     + R    Y+  +  RL+ E   LG Q  LYGF++   FAC   PC  +
Sbjct: 122 NTDVPGA----GSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGS 177

Query: 177 VDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHL-------LWKGRPRAGE--RDNRC 227
           + C +SRP+EKT+F+   F V     L +  EL  L        WK +  + +    +  
Sbjct: 178 ITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSSSSKYFLTSES 237

Query: 228 NRAHEEAQKLLP 239
            R H++A   LP
Sbjct: 238 TRRHKKATDSLP 249


>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
          Length = 439

 Score =  111 bits (278), Expect = 7e-25
 Identities = 45/99 (45%), Positives = 69/99 (69%)

Query: 4   WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
           W+FL  LL+ +   S  VG++WL V+++FRI++ A  G A++ DEQ +F CNT QPGC  
Sbjct: 6   WSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDN 65

Query: 64  TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGK 102
            CYD   P+SH RFW+F I+++S P V+++ Y++HR  +
Sbjct: 66  VCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLAR 104



 Score =  105 bits (262), Expect = 5e-23
 Identities = 65/164 (39%), Positives = 81/164 (49%), Gaps = 9/164 (5%)

Query: 103 EAGGAEAAAQCAPGLPEAQCAPCALRARRARRCYLLSVALRLLAELTFLGGQALLYGFRV 162
           +A GA+  A   PG          ++     R Y+  +  R   E+ FL GQ LLYGF V
Sbjct: 180 KAVGADGKAAGTPGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEV 239

Query: 163 APHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGE 222
            P F C+  PCPH VDCFVSRPTEKTVF+L  + V  L  LL++ E+ H L  G  +   
Sbjct: 240 RPFFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAH-LGLGSAQDAV 298

Query: 223 RDNRCNRAHEEAQKLLPPPPPPPPPPALPSRRPGPEPCAPPAYA 266
           R  R   A        P P P PPP A P+   G     PP Y+
Sbjct: 299 RGRRGPPAS------APAPAPRPPPCAFPAAAAG--LACPPDYS 334


>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 41/92 (44%), Positives = 59/92 (64%)

Query: 10  LLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRA 69
           LL      S  VGRL   V+L FR+++LA  G  V+ DEQ EFVC+T QPGC+  C+D  
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 70  FPVSHYRFWLFHILLLSAPPVLFVVYSMHRAG 101
            P+S  RFW+F ++L++ P VL++ Y+   +G
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVLYMGYTPWESG 119


>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 41/92 (44%), Positives = 59/92 (64%)

Query: 10  LLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRA 69
           LL      S  VGRL   V+L FR+++LA  G  V+ DEQ EFVC+T QPGC+  C+D  
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 70  FPVSHYRFWLFHILLLSAPPVLFVVYSMHRAG 101
            P+S  RFW+F ++L++ P VL++ Y+   +G
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVLYMGYTPWESG 119


>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
          Length = 222

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 41/92 (44%), Positives = 59/92 (64%)

Query: 10  LLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCYDRA 69
           LL      S  VGRL   V+L FR+++LA  G  V+ DEQ EFVC+T QPGC+  C+D  
Sbjct: 28  LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87

Query: 70  FPVSHYRFWLFHILLLSAPPVLFVVYSMHRAG 101
            P+S  RFW+F ++L++ P VL++ Y+   +G
Sbjct: 88  HPLSPLRFWVFQVILVAVPSVLYMGYTPWESG 119


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.141    0.465 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,570,862
Number of Sequences: 37866
Number of extensions: 991423
Number of successful extensions: 36590
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 943
Number of HSP's successfully gapped in prelim test: 589
Number of HSP's that attempted gapping in prelim test: 15524
Number of HSP's gapped (non-prelim): 11870
length of query: 294
length of database: 18,247,518
effective HSP length: 101
effective length of query: 193
effective length of database: 14,423,052
effective search space: 2783649036
effective search space used: 2783649036
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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