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Search of human proteins with 148839280
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
(994 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens] 2072 0.0
gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens] 2053 0.0
gi|32261332 seizure related 6 homolog (mouse)-like precursor [Ho... 847 0.0
gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2 ... 779 0.0
gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [H... 778 0.0
gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3 ... 767 0.0
gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4 ... 674 0.0
gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens] 271 2e-72
gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens] 249 7e-66
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 233 7e-61
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 233 7e-61
gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sap... 233 7e-61
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr... 106 1e-22
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr... 102 2e-21
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr... 101 3e-21
gi|54792123 complement component (3d/Epstein Barr virus) recepto... 100 7e-21
gi|148886654 polydom [Homo sapiens] 99 2e-20
gi|86793109 complement receptor 1 isoform S precursor [Homo sapi... 98 4e-20
gi|86793036 complement receptor 1 isoform F precursor [Homo sapi... 98 4e-20
gi|148922949 complement component (3b/4b) receptor 1-like [Homo ... 96 2e-19
gi|42544177 complement component (3d/Epstein Barr virus) recepto... 92 3e-18
gi|6912724 tolloid-like 2 [Homo sapiens] 89 2e-17
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H... 89 3e-17
gi|4502495 complement component 1, s subcomponent precursor [Hom... 87 6e-17
gi|41393602 complement component 1, s subcomponent precursor [Ho... 87 6e-17
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 87 8e-17
gi|168693643 decay accelerating factor for complement isoform 2 ... 85 3e-16
gi|10835143 decay accelerating factor for complement isoform 1 p... 85 3e-16
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 82 2e-15
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 81 4e-15
>gi|148839280 seizure related 6 homolog isoform 1 [Homo sapiens]
Length = 994
Score = 2072 bits (5368), Expect = 0.0
Identities = 994/994 (100%), Positives = 994/994 (100%)
Query: 1 MRPVALLLLPSLLALLAHGLSLEAPTVGKGQAPGIEETDGELTAAPTPEQPERGVHFVTT 60
MRPVALLLLPSLLALLAHGLSLEAPTVGKGQAPGIEETDGELTAAPTPEQPERGVHFVTT
Sbjct: 1 MRPVALLLLPSLLALLAHGLSLEAPTVGKGQAPGIEETDGELTAAPTPEQPERGVHFVTT 60
Query: 61 APTLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQDSRPVFT 120
APTLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQDSRPVFT
Sbjct: 61 APTLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQDSRPVFT 120
Query: 121 SPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGEIASTTPPSRA 180
SPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGEIASTTPPSRA
Sbjct: 121 SPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGEIASTTPPSRA 180
Query: 181 WTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQT 240
WTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQT
Sbjct: 181 WTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQT 240
Query: 241 PGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV 300
PGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV
Sbjct: 241 PGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV 300
Query: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP 360
EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP 360
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
Query: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE
Sbjct: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
Query: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG
Sbjct: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
Query: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 660
AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 660
Query: 661 QYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGW 720
QYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGW
Sbjct: 661 QYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGW 720
Query: 721 KSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHS 780
KSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHS
Sbjct: 721 KSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHS 780
Query: 781 RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG 840
RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG
Sbjct: 781 RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG 840
Query: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASL 900
LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASL
Sbjct: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASL 900
Query: 901 DGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLP 960
DGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLP
Sbjct: 901 DGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLP 960
Query: 961 RPRPRPYNRITIESAFDNPTYETGSLSFAGDERI 994
RPRPRPYNRITIESAFDNPTYETGSLSFAGDERI
Sbjct: 961 RPRPRPYNRITIESAFDNPTYETGSLSFAGDERI 994
>gi|148839346 seizure related 6 homolog isoform 2 [Homo sapiens]
Length = 993
Score = 2053 bits (5320), Expect = 0.0
Identities = 984/984 (100%), Positives = 984/984 (100%)
Query: 1 MRPVALLLLPSLLALLAHGLSLEAPTVGKGQAPGIEETDGELTAAPTPEQPERGVHFVTT 60
MRPVALLLLPSLLALLAHGLSLEAPTVGKGQAPGIEETDGELTAAPTPEQPERGVHFVTT
Sbjct: 1 MRPVALLLLPSLLALLAHGLSLEAPTVGKGQAPGIEETDGELTAAPTPEQPERGVHFVTT 60
Query: 61 APTLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQDSRPVFT 120
APTLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQDSRPVFT
Sbjct: 61 APTLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLANQDSRPVFT 120
Query: 121 SPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGEIASTTPPSRA 180
SPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGEIASTTPPSRA
Sbjct: 121 SPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGEIASTTPPSRA 180
Query: 181 WTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQT 240
WTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQT
Sbjct: 181 WTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQT 240
Query: 241 PGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV 300
PGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV
Sbjct: 241 PGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV 300
Query: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP 360
EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP
Sbjct: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP 360
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI
Sbjct: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
Query: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE
Sbjct: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
Query: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG
Sbjct: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
Query: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS
Sbjct: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
Query: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 660
AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG
Sbjct: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLG 660
Query: 661 QYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGW 720
QYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGW
Sbjct: 661 QYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGW 720
Query: 721 KSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHS 780
KSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHS
Sbjct: 721 KSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHS 780
Query: 781 RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG 840
RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG
Sbjct: 781 RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG 840
Query: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASL 900
LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASL
Sbjct: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASL 900
Query: 901 DGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLP 960
DGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLP
Sbjct: 901 DGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLP 960
Query: 961 RPRPRPYNRITIESAFDNPTYETG 984
RPRPRPYNRITIESAFDNPTYETG
Sbjct: 961 RPRPRPYNRITIESAFDNPTYETG 984
>gi|32261332 seizure related 6 homolog (mouse)-like precursor [Homo
sapiens]
Length = 1024
Score = 847 bits (2188), Expect = 0.0
Identities = 444/1021 (43%), Positives = 622/1021 (60%), Gaps = 53/1021 (5%)
Query: 1 MRPVALLLLPSLLALLAHGLSLEAPTVGKGQA----PGIEETDGELTAAPTPEQPERGVH 56
+R ++L L L L + +LE + +G A P + + +P E PE V
Sbjct: 11 LRGISLFLA---LLLGSPAAALERDALPEGDASPLGPYLLPSGAPERGSPGKEHPEERV- 66
Query: 57 FVTTAPTLKLLNHHPLLEEFLQEGLEKGDEELRPAL-PFQPDPPAPFTPSP----LPRL- 110
VT P+ +L E + +G PAL P P+ P P LP L
Sbjct: 67 -VTAPPSSS--QSAEVLGELVLDGTAPSAHHDIPALSPLLPEEARPKHALPPKKKLPSLK 123
Query: 111 ----ANQDSRPVFTSPT--------PAMAAVPTQPQSKEGPWSPESESPML--------- 149
A + RP TS PA + S E P P P++
Sbjct: 124 QVNSARKQLRPKATSAATVQRAGSQPASQGLDLLSSSTEKPGPPGDPDPIVASEEASEVP 183
Query: 150 ------RITAPLPPGPSMAVPTLGPGEIASTTPPSRAWTPTQEGPGDMGRPWVAEVVSQG 203
P P P P +A T P P + GP DM + E S
Sbjct: 184 LWLDRKESAVPTTPAPLQISPFTSQPYVAHTLPQRPE--PGEPGP-DMAQEAPQEDTSPM 240
Query: 204 AGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSS 263
A + + +AS + +ETTT+T I TT ITT Q P CS +FS PEG +DS
Sbjct: 241 ALMDKGENELTGSASEESQETTTSTIITTTVITTEQAPALCSVSFSNPEGYIDSSDYPLL 300
Query: 264 PTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVI 323
P + L+C + ++VY GYGVE++V++++L +GE +++ G+ GP LANQ+ L+ GQVI
Sbjct: 301 PLNNFLECTYNVTVYTGYGVELQVKSVNLSDGELLSIRGVDGPTLTVLANQTLLVEGQVI 360
Query: 324 RSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHC 383
RSPT+ ++ F++ G GTF HYQA++LSC+FPRRP GDVTV LH GG A FHC
Sbjct: 361 RSPTNTISVYFRTFQDD-GLGTFQLHYQAFMLSCNFPRRPDSGDVTVMDLHSGGVAHFHC 419
Query: 384 ATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTC 443
GY+L+GA+ LTC+NA++P W S+EP+C A CGG + NAT GR++SP +P N + + C
Sbjct: 420 HLGYELQGAKMLTCINASKPHWSSQEPICSAPCGGAVHNATIGRVLSPSYPENTNGSQFC 479
Query: 444 HWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGK 503
W +EAPEGQ+LHLHFE++ L D DR+ + +G ++ +YDS + E +P EGLLS G
Sbjct: 480 IWTIEAPEGQKLHLHFERL-LLHDKDRMTVHSGQTNKSALLYDSLQTESVPFEGLLSEGN 538
Query: 504 HFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGY 563
+E ++D + AA+ +R+EAF++GHCYEP+++ GNF++S PTY +GT VEF+CDPG+
Sbjct: 539 TIRIEFTSDQARAASTFNIRFEAFEKGHCYEPYIQNGNFTTSDPTYNIGTIVEFTCDPGH 598
Query: 564 TLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGV 623
+LEQG IIEC++ DP WN+TEP CRA+C GE++ AGVVLSPNWPEPY G+DCIW +
Sbjct: 599 SLEQGPAIIECINVRDPYWNDTEPLCRAMCGGELSAVAGVVLSPNWPEPYVEGEDCIWKI 658
Query: 624 HVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQ 683
HV E+KRI LDI+ L + D+LT YDGD++ +LGQY G KL++S D+TIQF
Sbjct: 659 HVGEEKRIFLDIQFLNLSNSDILTIYDGDEVMPHILGQYLGNSGPQKLYSSTPDLTIQFH 718
Query: 684 SDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQ 743
SDP + G QGF++++ EV RND+C +LPEI NGWK+ S ELV G +TYQC PGY
Sbjct: 719 SDPAGLIFGKGQGFIMNYIEVSRNDSCSDLPEIQNGWKTTSHTELVRGARITYQCDPGYD 778
Query: 744 VVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGF 803
+VGS L CQWDL+WS D P C+++ C DPG+V+HS RLIS P VG T+QY C+ GF
Sbjct: 779 IVGSDTLTCQWDLSWSSDPPFCEKIMYCTDPGEVDHSTRLISDPVLLVGTTIQYTCNPGF 838
Query: 804 VLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIH 863
VL GSS+LTC+ R+ G+P W+ R P C+ E+ C PENG + K+L+ G ++
Sbjct: 839 VLEGSSLLTCYSRETGTPIWTSRLPHCVSEESLACDNPGLPENGYQILYKRLYLPGESLT 898
Query: 864 FSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDA 923
F C G+ L G+ +I+C+ G PSHW+ P P+C+ + D F +L+VA+A AA ++L+
Sbjct: 899 FMCYEGFELMGEVTIRCILGQPSHWNGPLPVCK-VNQDSF--EHALEVAEA-AAETSLEG 954
Query: 924 AHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLPRPRPRPYNRITIESAFDNPTYET 983
++A AIF+P++ + LL+GG Y Y +R + S+L+LP PY++IT+E+ FDNP YET
Sbjct: 955 GNMALAIFIPVLIISLLLGGAYIYITRCRYYSNLRLPLMYSHPYSQITVETEFDNPIYET 1014
Query: 984 G 984
G
Sbjct: 1015 G 1015
>gi|166235136 seizure related 6 homolog (mouse)-like 2 isoform 2
[Homo sapiens]
Length = 910
Score = 779 bits (2012), Expect = 0.0
Identities = 420/943 (44%), Positives = 562/943 (59%), Gaps = 87/943 (9%)
Query: 51 PERGVHFVTTAP-TLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPR 109
PE G T A L L H LL + G G + P L P PS LPR
Sbjct: 37 PEPGSETPTVASEALAELLHGALLRRGPEMGYLPGSDR-DPTLATPPAGQTLAVPS-LPR 94
Query: 110 LANQDSRPVFTSPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPG 169
+ P+ T+ TP GP +PE +P TAP PP P+ P LGP
Sbjct: 95 ATEPGTGPLTTAVTP-------NGVRGAGPTAPELLTPPPGTTAPPPPSPASPGPPLGP- 146
Query: 170 EIASTTPPSRAWTPTQEGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDEETTTTTT 229
G +EETTTT
Sbjct: 147 ------------------------------------------------EGGEEETTTTII 158
Query: 230 IITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSPTD--VGL-DCFFYISVYPGYGVEIK 286
TT TTV +P C+ N S EG ++SP DL SP +GL DC + I VYPGYG+EI+
Sbjct: 159 TTTTVTTTVTSPVLCNNNISEGEGYVESP-DLGSPVSRTLGLLDCTYSIHVYPGYGIEIQ 217
Query: 287 VQNISL-REGETVTVEGLGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGP 343
VQ ++L +E E + + G G P P LAN S L GQV+RSPT++ L FQS P G
Sbjct: 218 VQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLLHFQSPRVPRGG 277
Query: 344 GTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQP 403
G F HYQAYLLSC FP RPA+GDV+VT LHPGG+A FHC +GYQL+G L CLN T+P
Sbjct: 278 G-FRIHYQAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRP 336
Query: 404 FWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVS 463
W+ + P C+A+CGG I NAT GRIVSP G NLTC W++EA EG+RLHLHFE+VS
Sbjct: 337 SWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVS 396
Query: 464 LAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALR 523
L ED+DRL++R+G + +P +YDS +++ +P GL+S + +VEL +++ ++LR
Sbjct: 397 LDEDNDRLMVRSGGSPLSPVIYDS-DMDDVPERGLISDAQSLYVELLSETPANPLLLSLR 455
Query: 524 YEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSI--IIECVDPHDPQ 581
+EAF++ C+ PF+ +GN +++ P Y G FSC PGY LE IECVDP +P
Sbjct: 456 FEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPH 515
Query: 582 WNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIG 641
WN+TEPAC+A+C GE+++ AGVVLSP+WP+ Y GQDC+WGVHV+E+KRI+L + +L +
Sbjct: 516 WNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVR 575
Query: 642 PGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHF 701
GD+LT +DGD +ARVL Q GP+ +L +S D+T+QFQ+ PG G QGFV+HF
Sbjct: 576 EGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHF 635
Query: 702 FEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSED 761
EVPRNDTCPELP GW++ S +L+ GTV+TYQC PGY+++GS +L CQWDL+WS
Sbjct: 636 KEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAA 695
Query: 762 LPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSP 821
P+CQ++ +C DPG++ + R S FPVG+ VQY C G+ L G+++LTC+ R G+P
Sbjct: 696 PPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTP 755
Query: 822 KWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCV 881
KWSDR PKC L + +PC PENG ++ K + AG ++ F C G+ L G+ +I CV
Sbjct: 756 KWSDRVPKCAL-KYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCV 814
Query: 882 PGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLV 941
PGHPS W+ PP+C+ V + S L+ ++A AI LPL +++L
Sbjct: 815 PGHPSQWTSQPPLCK--------------VTQTTDPSRQLEGGNLALAILLPLGLVIVLG 860
Query: 942 GGVYFYFSRLQGKSSLQLPRPRPRPYNRITIESAFDNPTYETG 984
GVY Y+++LQGKS Y+ IT+ES F NP YE G
Sbjct: 861 SGVYIYYTKLQGKSLFGF--SGSHSYSPITVESDFSNPLYEAG 901
>gi|6912612 seizure related 6 homolog (mouse)-like 2 isoform 1 [Homo
sapiens]
Length = 853
Score = 778 bits (2008), Expect = 0.0
Identities = 384/774 (49%), Positives = 522/774 (67%), Gaps = 15/774 (1%)
Query: 219 GDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSPTD--VGL-DCFFYI 275
G +EETTTT TT TTV +P C+ N S EG ++SP DL SP +GL DC + I
Sbjct: 78 GGEEETTTTIITTTTVTTTVTSPVLCNNNISEGEGYVESP-DLGSPVSRTLGLLDCTYSI 136
Query: 276 SVYPGYGVEIKVQNISL-REGETVTVEGLGGPDPLP--LANQSFLLRGQVIRSPTHQAAL 332
VYPGYG+EI+VQ ++L +E E + + G G P P LAN S L GQV+RSPT++ L
Sbjct: 137 HVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLL 196
Query: 333 RFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGA 392
FQS P G G F HYQAYLLSC FP RPA+GDV+VT LHPGG+A FHC +GYQL+G
Sbjct: 197 HFQSPRVPRGGG-FRIHYQAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGE 255
Query: 393 RHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEG 452
L CLN T+P W+ + P C+A+CGG I NAT GRIVSP G NLTC W++EA EG
Sbjct: 256 ETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEG 315
Query: 453 QRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTD 512
+RLHLHFE+VSL ED+DRL++R+G + +P +YDS +++ +P GL+S + +VEL ++
Sbjct: 316 RRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDS-DMDDVPERGLISDAQSLYVELLSE 374
Query: 513 SSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSI-- 570
+ ++LR+EAF++ C+ PF+ +GN +++ P Y G FSC PGY LE
Sbjct: 375 TPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPN 434
Query: 571 IIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKR 630
IECVDP +P WN+TEPAC+A+C GE+++ AGVVLSP+WP+ Y GQDC+WGVHV+E+KR
Sbjct: 435 AIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKR 494
Query: 631 IMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSV 690
I+L + +L + GD+LT +DGD +ARVL Q GP+ +L +S D+T+QFQ+ PG
Sbjct: 495 ILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPN 554
Query: 691 LGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVL 750
G QGFV+HF EVPRNDTCPELP GW++ S +L+ GTV+TYQC PGY+++GS +L
Sbjct: 555 PGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDIL 614
Query: 751 MCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSI 810
CQWDL+WS P+CQ++ +C DPG++ + R S FPVG+ VQY C G+ L G+++
Sbjct: 615 TCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAM 674
Query: 811 LTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGY 870
LTC+ R G+PKWSDR PKC L + +PC PENG ++ K + AG ++ F C G+
Sbjct: 675 LTCYSRDTGTPKWSDRVPKCAL-KYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGF 733
Query: 871 VLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDAAHIAAAI 930
L G+ +I CVPGHPS W+ PP+C+ A + ++R L+V + S L+ ++A AI
Sbjct: 734 ELIGEVTITCVPGHPSQWTSQPPLCKVA-YEELLDNRKLEVTQTTDPSRQLEGGNLALAI 792
Query: 931 FLPLVAMVLLVGGVYFYFSRLQGKSSLQLPRPRPRPYNRITIESAFDNPTYETG 984
LPL +++L GVY Y+++LQGKS Y+ IT+ES F NP YE G
Sbjct: 793 LLPLGLVIVLGSGVYIYYTKLQGKSLFGF--SGSHSYSPITVESDFSNPLYEAG 844
>gi|166235138 seizure related 6 homolog (mouse)-like 2 isoform 3
[Homo sapiens]
Length = 840
Score = 767 bits (1980), Expect = 0.0
Identities = 381/774 (49%), Positives = 515/774 (66%), Gaps = 28/774 (3%)
Query: 219 GDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSPTD--VGL-DCFFYI 275
G +EETTTT TT TTV +P C+ N S EG ++SP DL SP +GL DC + I
Sbjct: 78 GGEEETTTTIITTTTVTTTVTSPVLCNNNISEGEGYVESP-DLGSPVSRTLGLLDCTYSI 136
Query: 276 SVYPGYGVEIKVQNISL-REGETVTVEGLGGPDPLP--LANQSFLLRGQVIRSPTHQAAL 332
VYPGYG+EI+VQ ++L +E E + + G G P P LAN S L GQV+RSPT++ L
Sbjct: 137 HVYPGYGIEIQVQTLNLSQEEELLVLAGGGSPGLAPRLLANSSMLGEGQVLRSPTNRLLL 196
Query: 333 RFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGA 392
FQS P G G F HYQAYLLSC FP RPA+GDV+VT LHPGG+A FHC +GYQL+G
Sbjct: 197 HFQSPRVPRGGG-FRIHYQAYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGE 255
Query: 393 RHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEG 452
L CLN T+P W+ + P C+A+CGG I NAT GRIVSP G NLTC W++EA EG
Sbjct: 256 ETLICLNGTRPSWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEG 315
Query: 453 QRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTD 512
+RLHLHFE+VSL ED+DRL++R+G + +P +YDS +++ +P GL+S + +VEL ++
Sbjct: 316 RRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDS-DMDDVPERGLISDAQSLYVELLSE 374
Query: 513 SSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSI-- 570
+ ++LR+EAF++ C+ PF+ +GN +++ P Y G FSC PGY LE
Sbjct: 375 TPANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPN 434
Query: 571 IIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKR 630
IECVDP +P WN+TEPAC+A+C GE+++ AGVVLSP+WP+ Y GQDC+WGVHV+E+KR
Sbjct: 435 AIECVDPTEPHWNDTEPACKAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKR 494
Query: 631 IMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSV 690
I+L + +L + GD+LT +DGD +ARVL Q GP+ +L +S D+T+QFQ+ PG
Sbjct: 495 ILLQVEILNVREGDMLTLFDGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPN 554
Query: 691 LGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVL 750
G QGFV+HF EVPRNDTCPELP GW++ S +L+ GTV+TYQC PGY+++GS +L
Sbjct: 555 PGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDIL 614
Query: 751 MCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSI 810
CQWDL+WS P+CQ++ +C DPG++ + R S FPVG+ VQY C G+ L G+++
Sbjct: 615 TCQWDLSWSAAPPACQKIMTCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAM 674
Query: 811 LTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGY 870
LTC+ R G+PKWSDR PKC L + +PC PENG ++ K + AG ++ F C G+
Sbjct: 675 LTCYSRDTGTPKWSDRVPKCAL-KYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGF 733
Query: 871 VLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDAAHIAAAI 930
L G+ +I CVPGHPS W+ PP+C+ V + S L+ ++A AI
Sbjct: 734 ELIGEVTITCVPGHPSQWTSQPPLCK--------------VTQTTDPSRQLEGGNLALAI 779
Query: 931 FLPLVAMVLLVGGVYFYFSRLQGKSSLQLPRPRPRPYNRITIESAFDNPTYETG 984
LPL +++L GVY Y+++LQGKS Y+ IT+ES F NP YE G
Sbjct: 780 LLPLGLVIVLGSGVYIYYTKLQGKSLFGF--SGSHSYSPITVESDFSNPLYEAG 831
>gi|166235140 seizure related 6 homolog (mouse)-like 2 isoform 4
[Homo sapiens]
Length = 809
Score = 674 bits (1739), Expect = 0.0
Identities = 315/635 (49%), Positives = 436/635 (68%), Gaps = 7/635 (1%)
Query: 352 AYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPV 411
AYLLSC FP RPA+GDV+VT LHPGG+A FHC +GYQL+G L CLN T+P W+ + P
Sbjct: 171 AYLLSCGFPPRPAHGDVSVTDLHPGGTATFHCDSGYQLQGEETLICLNGTRPSWNGETPS 230
Query: 412 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
C+A+CGG I NAT GRIVSP G NLTC W++EA EG+RLHLHFE+VSL ED+DRL
Sbjct: 231 CMASCGGTIHNATLGRIVSPEPGGAVGPNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRL 290
Query: 472 IIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGH 531
++R+G + +P +YDS +++ +P GL+S + +VEL +++ ++LR+EAF++
Sbjct: 291 MVRSGGSPLSPVIYDS-DMDDVPERGLISDAQSLYVELLSETPANPLLLSLRFEAFEEDR 349
Query: 532 CYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSI--IIECVDPHDPQWNETEPAC 589
C+ PF+ +GN +++ P Y G FSC PGY LE IECVDP +P WN+TEPAC
Sbjct: 350 CFAPFLAHGNVTTTDPEYRPGALATFSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPAC 409
Query: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFY 649
+A+C GE+++ AGVVLSP+WP+ Y GQDC+WGVHV+E+KRI+L + +L + GD+LT +
Sbjct: 410 KAMCGGELSEPAGVVLSPDWPQSYSPGQDCVWGVHVQEEKRILLQVEILNVREGDMLTLF 469
Query: 650 DGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDT 709
DGD +ARVL Q GP+ +L +S D+T+QFQ+ PG G QGFV+HF EVPRNDT
Sbjct: 470 DGDGPSARVLAQLRGPQPRRRLLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDT 529
Query: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
CPELP GW++ S +L+ GTV+TYQC PGY+++GS +L CQWDL+WS P+CQ++
Sbjct: 530 CPELPPPEWGWRTASHGDLIRGTVLTYQCEPGYELLGSDILTCQWDLSWSAAPPACQKIM 589
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
+C DPG++ + R S FPVG+ VQY C G+ L G+++LTC+ R G+PKWSDR PK
Sbjct: 590 TCADPGEIANGHRTASDAGFPVGSHVQYRCLPGYSLEGAAMLTCYSRDTGTPKWSDRVPK 649
Query: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 889
C L + +PC PENG ++ K + AG ++ F C G+ L G+ +I CVPGHPS W+
Sbjct: 650 CAL-KYEPCLNPGVPENGYQTLYKHHYQAGESLRFFCYEGFELIGEVTITCVPGHPSQWT 708
Query: 890 DPPPICRAASLDGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLVGGVYFYFS 949
PP+C+ A + ++R L+V + S L+ ++A AI LPL +++L GVY Y++
Sbjct: 709 SQPPLCKVA-YEELLDNRKLEVTQTTDPSRQLEGGNLALAILLPLGLVIVLGSGVYIYYT 767
Query: 950 RLQGKSSLQLPRPRPRPYNRITIESAFDNPTYETG 984
+LQGKS Y+ IT+ES F NP YE G
Sbjct: 768 KLQGKSLFGF--SGSHSYSPITVESDFSNPLYEAG 800
Score = 124 bits (311), Expect = 4e-28
Identities = 166/619 (26%), Positives = 244/619 (39%), Gaps = 72/619 (11%)
Query: 51 PERGVHFVTTAP-TLKLLNHHPLLEEFLQEGLEKGDEELRPALPFQPDPPAPFTPSPLPR 109
PE G T A L L H LL + G G + P L P PS LPR
Sbjct: 37 PEPGSETPTVASEALAELLHGALLRRGPEMGYLPGSDR-DPTLATPPAGQTLAVPS-LPR 94
Query: 110 LANQDSRPVFTSPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGP- 168
+ P+ T+ TP GP +PE +P TAP PP P+ P LGP
Sbjct: 95 ATEPGTGPLTTAVTP-------NGVRGAGPTAPELLTPPPGTTAPPPPSPASPGPPLGPE 147
Query: 169 -GEIASTTP--PSRAWTPTQEGP------GDMGRPWVAEVVSQGAGIGIQGTITSSTASG 219
GE +TT + T T P G RP +V G GT T SG
Sbjct: 148 GGEEETTTTIITTTTVTTTVTSPAYLLSCGFPPRPAHGDVSVTDLHPG--GTATFHCDSG 205
Query: 220 DDEETTTTTTIITTTITTVQTPGPCSWNFSGPE------GSLDSPT--DLSSPTDVG--- 268
+ T + T SWN P G++ + T + SP G
Sbjct: 206 YQLQGEETLICLNGTRP--------SWNGETPSCMASCGGTIHNATLGRIVSPEPGGAVG 257
Query: 269 --LDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFL----LRGQV 322
L C + I G + + + +SL E + GG P+ S + RG +
Sbjct: 258 PNLTCRWVIEAAEGRRLHLHFERVSLDEDNDRLMVRSGGSPLSPVIYDSDMDDVPERGLI 317
Query: 323 IRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVT--SLHPGGSAR 380
+ + L ++ PA P ++A+ F A+G+VT T PG A
Sbjct: 318 SDAQSLYVELLSET---PANPLLLSLRFEAFEEDRCFAPFLAHGNVTTTDPEYRPGALAT 374
Query: 381 FHCATGYQLK---GARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNY 437
F C GY L+ + C++ T+P W+ EP C A CGG + + G ++SP +P +Y
Sbjct: 375 FSCLPGYALEPPGPPNAIECVDPTEPHWNDTEPACKAMCGGEL-SEPAGVVLSPDWPQSY 433
Query: 438 SNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEG 497
S C W + E +R+ L E +++ E D L + +GD A + + P
Sbjct: 434 SPGQDCVWGVHVQEEKRILLQVEILNVRE-GDMLTLFDGDGPSARVLAQLRGPQ--PRRR 490
Query: 498 LLSSGKHFFVELST----DSSGAAAGMALRY-EAFQQGHCYE-PFVKYGNFSSSTPTYPV 551
LLSSG ++ + G G L + E + C E P ++G ++S
Sbjct: 491 LLSSGPDLTLQFQAPPGPPNPGLGQGFVLHFKEVPRNDTCPELPPPEWGWRTASHGDLIR 550
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCS----GEITDSAGVVLSP 607
GT + + C+PGY L GS I+ C D W+ PAC+ + + GEI +
Sbjct: 551 GTVLTYQCEPGYEL-LGSDILTC--QWDLSWSAAPPACQKIMTCADPGEIANGHRTASDA 607
Query: 608 NWPEPYGRGQDCIWGVHVE 626
+P C+ G +E
Sbjct: 608 GFPVGSHVQYRCLPGYSLE 626
>gi|92110053 CUB and Sushi multiple domains 2 [Homo sapiens]
Length = 3487
Score = 271 bits (693), Expect = 2e-72
Identities = 218/761 (28%), Positives = 328/761 (43%), Gaps = 82/761 (10%)
Query: 200 VSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGS 254
+ +G G+ T+T S G E T T + +P P C + +G +G+
Sbjct: 1049 IRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGT 1108
Query: 255 LDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLAN 313
L SP + + +C + I PG G+++K + L EG+ + V +G L
Sbjct: 1109 LLSP-NFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVF 1167
Query: 314 QSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTS 372
+ G + S + L F + G F H+ ++ L+ C P P +G
Sbjct: 1168 SHSEMMGVTLNSTSSSLWLDFITDAENTSKG-FELHFSSFELIKCEDPGTPKFGYKVHDE 1226
Query: 373 LH-PGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSP 431
H G S F C GY L+G+ L CL+ + WD P C+A CGG +R +G+++SP
Sbjct: 1227 GHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSP 1286
Query: 432 GFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE 491
G+P Y +NL C W +EA G + LHF E D L I +G VE+ +
Sbjct: 1287 GYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGP-VESGVLLKELSGP 1345
Query: 492 YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
LP + L S+ ++ STD + G A+++ C +P + N S S ++
Sbjct: 1346 ALP-KDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQ-NGSRSGDSWEA 1403
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRAVCSGEITDSAGVVLSPNWP 610
G + F CDPGY L QGS I CV + W + P C A C G++T +GV+LSPN+P
Sbjct: 1404 GDSTVFQCDPGYAL-QGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYP 1462
Query: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
EPY G++C W V V D I L + + PG D L YDG D + ++G + G +
Sbjct: 1463 EPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPG 1522
Query: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
++ +S + + F+SD S GFVI + E PR ++C + I NG + S +L
Sbjct: 1523 RIESSSNSLFLAFRSDASVS----NAGFVIDYTENPR-ESCFDPGSIKNGTRVGSDLKL- 1576
Query: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
G+ VTY C+ GY+V G+S L C W+ P C C G S ++
Sbjct: 1577 -GSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVC--TAPC--GGQYVGSDGVVL 1631
Query: 786 SPKFPVGATVQYIC------DQGFVLMG---------SSILTCHDRQA---------GSP 821
SP +P T IC + +V+ G + ++ HD +
Sbjct: 1632 SPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGS 1691
Query: 822 KWSDRAPKCLLEQ---------LKPCHGL-----SAPENGARSPEKQLHP---------- 857
+ P Q L P G + P A P
Sbjct: 1692 HTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDF 1751
Query: 858 -AGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPIC 895
GA + F C GY L+G I+C VPG + W+ P C
Sbjct: 1752 SVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTC 1792
Score = 207 bits (526), Expect = 5e-53
Identities = 197/726 (27%), Positives = 300/726 (41%), Gaps = 106/726 (14%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVG--LDCFFYISVYPGYGVEIKVQNIS---------L 292
C +NF+ P G + SP + P D G L C + I P + + +I +
Sbjct: 578 CFFNFTSPSGVVLSP---NYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVI 634
Query: 293 REGETVTVEGLG--GPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHY 350
++G T LG + LP + I S H A L FQ+ G F+ +
Sbjct: 635 KDGATAEAPVLGTFSGNQLPSS----------ITSSGHVARLEFQT-DHSTGKRGFNITF 683
Query: 351 QAYLLS-CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQ-LKGARHLTC-LNATQPFWDS 407
+ + C P P G SL G S F C G+ +G+ +TC L W+S
Sbjct: 684 TTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNS 743
Query: 408 KEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAED 467
C A CGG + + +G I+SPG+PG Y + L+C W++EA G + + F++ +
Sbjct: 744 AVLRCEAPCGGHL-TSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVN 802
Query: 468 DDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAF 527
D L +R+G AP + Y +P + L+S+ + ++ STD S + G LRYE
Sbjct: 803 YDTLEVRDGRTYSAPLI-GVYHGTQVP-QFLISTSNYLYLLFSTDKSHSDIGFQLRYETI 860
Query: 528 --QQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNET 585
Q HC +P + Y VG V FSCD GYTL G + EC +P+ QW+
Sbjct: 861 TLQSDHCLDPGIPVNGQRHGNDFY-VGALVTFSCDSGYTLSDGEPL-EC-EPNF-QWSRA 916
Query: 586 EPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-D 644
P+C A+C G I S+G +LSP +P+ Y +C W + K + + G D
Sbjct: 917 LPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHD 976
Query: 645 VLTFYDGDDLTARVLGQYSGPRSHFKLFTSM---ADVTIQFQSDPGTSVLGYQQGFVIHF 701
L + T + L Q +G R + + ++F SD S +GF I F
Sbjct: 977 YLLITENGSFT-QPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMS----YEGFNITF 1031
Query: 702 FEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWS 759
E + C E PE+P + + G +T+ C+PGY++ G++ + C WS
Sbjct: 1032 SEYDL-EPCEE-PEVP-AYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWS 1088
Query: 760 EDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYIC---------------DQGFV 804
LP C V C + V ++ + SP FPV + C + F
Sbjct: 1089 SPLPRC--VAECGN--SVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFE 1144
Query: 805 LMGSSILTCHD----------------------RQAGSPKWSDRAPKC-----------L 831
L +L +D S W D
Sbjct: 1145 LSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFS 1204
Query: 832 LEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDP 891
+L C P+ G + ++ H AG+++ FSC PGY L+G + C+ G W P
Sbjct: 1205 SFELIKCEDPGTPKFGYKVHDEG-HFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRP 1263
Query: 892 PPICRA 897
P C A
Sbjct: 1264 LPTCVA 1269
Score = 201 bits (511), Expect = 3e-51
Identities = 155/555 (27%), Positives = 244/555 (43%), Gaps = 26/555 (4%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVY-PGYGVEIKVQNISLREGETVTVEG 302
C + GP G + SP + D C + I+ P +++ + L G G
Sbjct: 405 CDAHLRGPSGIITSP-NFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVG 463
Query: 303 LGGPDPLPLANQSFLLRG----QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
GG D ++L G +I S HQ L FQ+ + G + + SC
Sbjct: 464 DGGQDG-DQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCG 522
Query: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGG 418
P PAYG + H G + +F C ++L G + +TC Q W +K+P C+ +C
Sbjct: 523 DPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQ--WSAKKPGCVFSCFF 580
Query: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
+ +G ++SP +P +Y N+L C WL+ A R+HL F + + D L+I++G
Sbjct: 581 NF-TSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGAT 639
Query: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK 538
EA PV ++ LP + SSG +E TD S G + + F+ C +P V
Sbjct: 640 AEA-PVLGTFSGNQLP-SSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVP 697
Query: 539 YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSGEI 597
N + +G+++ F CD G+ QGS I CV WN C A C G +
Sbjct: 698 V-NGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHL 756
Query: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTA 656
T +G +LSP WP Y C W + + I + + D L DG +A
Sbjct: 757 TSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSA 816
Query: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
++G Y G + L ++ + + F +D S +G+Q + + +D C + P I
Sbjct: 817 PLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQ---SDHCLD-PGI 872
Query: 717 P-NGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPG 775
P NG + + + G +VT+ C GY + L C+ + WS LPSC+ + G
Sbjct: 873 PVNGQRHGN--DFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCG----G 926
Query: 776 DVEHSRRLISSPKFP 790
++ S I SP FP
Sbjct: 927 FIQGSSGTILSPGFP 941
Score = 194 bits (494), Expect = 3e-49
Identities = 170/605 (28%), Positives = 253/605 (41%), Gaps = 85/605 (14%)
Query: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF-WDSKEPVCIA 414
SC+ P P G + S G S F C GY L+G+ ++C+ F W P CIA
Sbjct: 1384 SCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIA 1443
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
CGG + +G I+SP +P Y C W + + L F +L D L I
Sbjct: 1444 PCGGDL-TGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
Query: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE 534
+G + P+ S+ LP + SS F+ +D+S + AG + Y + C++
Sbjct: 1503 DGRD-SLSPLIGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFD 1560
Query: 535 P-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHD--PQWNETEPACRA 591
P +K G S +G++V + C GY +E G+ + C+ D P WN P C A
Sbjct: 1561 PGSIKNGTRVGSD--LKLGSSVTYYCHGGYEVE-GTSTLSCILGPDGKPVWNNPRPVCTA 1617
Query: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
C G+ S GVVLSPN+P+ Y GQ C++ V V +D + DV+ +DG
Sbjct: 1618 PCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDG 1677
Query: 652 DDLTARVLGQYSGPRSHFKL-FTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDT- 709
+R+L SG + L + V I+F + L +GF + VPR
Sbjct: 1678 HSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSA----KGLAPARGFHFVYQAVPRTSAT 1733
Query: 710 -CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMC--------QWDLTWSE 760
C +PE G + S + G +V ++C GY + GS + C QW+++
Sbjct: 1734 QCSSVPEPRYGKRLGS--DFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVS--- 1788
Query: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFP------------------VGATVQYI---- 798
P+C V C G++ R I SP FP G +Q +
Sbjct: 1789 -APTC--VVPC--GGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVT 1843
Query: 799 ------------CDQGFVLMGS-------SILTCHDRQAGSPKWSD---RAPKCLLEQ-- 834
D ++GS ++L Q +SD A LE
Sbjct: 1844 EQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKT 1903
Query: 835 --LKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPP 892
L C + P NG ++ E+ L + F C PGY L+G A I C+PG W+ PP
Sbjct: 1904 VGLSSCPEPAVPSNGVKTGERYL--VNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPP 1961
Query: 893 PICRA 897
P+C A
Sbjct: 1962 PLCIA 1966
Score = 190 bits (482), Expect = 7e-48
Identities = 175/637 (27%), Positives = 257/637 (40%), Gaps = 75/637 (11%)
Query: 205 GIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSP 264
G ++GT T S G D + T PC + G +G + SP +
Sbjct: 1587 GYEVEGTSTLSCILGPDGKPVWNNPRPVCT-------APCGGQYVGSDGVVLSPNYPQNY 1639
Query: 265 TDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVIR 324
T G C ++++V Y V + + V V L++ S G+ +
Sbjct: 1640 TS-GQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLP 1698
Query: 325 SPT-HQAALRFQS--LPPPAGPGTFHFHYQAY----LLSCHFPRRPAYGDVTVTSLHPGG 377
T +Q ++F + L P G FHF YQA C P YG + G
Sbjct: 1699 LATSNQVLIKFSAKGLAPARG---FHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGA 1755
Query: 378 SARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
RF C +GY L+G+ + CL W+ P C+ CGG + G I+SPGFP
Sbjct: 1756 IVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERR-GTILSPGFPE 1814
Query: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNG-DNVEAPPVYDSYEVEYLP 494
Y N+L C W + PEG + + ++ D L + +G DN + S+ +P
Sbjct: 1815 PYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVT--MLGSFSGTTVP 1872
Query: 495 IEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTT 554
L S+ ++ +D S +AAG L Y+ C EP V N + Y V
Sbjct: 1873 AL-LNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVP-SNGVKTGERYLVNDV 1930
Query: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYG 614
V F C+PGY L QG I C+ +WN P C A C G + + GV+LSP +P Y
Sbjct: 1931 VSFQCEPGYAL-QGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYP 1989
Query: 615 RGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFT 673
DC W + + + P D + +G T+R++G++SG L +
Sbjct: 1990 SNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLS 2049
Query: 674 SMADVTIQFQSD-----PGTSVLGYQQGFVIH----------FFEVPRNDTCP------- 711
+ + T+ F SD PG L YQ H E+ R ++ P
Sbjct: 2050 TSHETTVYFHSDHSQNRPGFK-LEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYV 2108
Query: 712 ----------ELPEIPNGWKSPSQPELVHGT------VVTYQCYPGYQVVGSSVLMCQ-- 753
EL E P+ P +V G VT++C PGYQ+ G VL CQ
Sbjct: 2109 WDLDPGCEAYELQECPD--PEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHG 2166
Query: 754 WDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
+ W LP C+ C G++ S + SP FP
Sbjct: 2167 TNRNWDHPLPKCE--VPC--GGNITSSNGTVYSPGFP 2199
Score = 180 bits (456), Expect = 7e-45
Identities = 153/564 (27%), Positives = 247/564 (43%), Gaps = 38/564 (6%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--V 300
PC + +GP G + SP + P G +C + ++V P Y + + +L G
Sbjct: 1444 PCGGDLTGPSGVILSP-NYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIY 1502
Query: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFP 360
+G PL + L G+ I S ++ L F+S + G + + SC P
Sbjct: 1503 DGRDSLSPLIGSFYGSQLPGR-IESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDP 1561
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACGG 418
G + L G S ++C GY+++G L+C+ +P W++ PVC A CGG
Sbjct: 1562 GSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGG 1621
Query: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
+ G ++SP +P NY++ C + + P+ + F A +D + + +G +
Sbjct: 1622 QYVGSD-GVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDV-VEVHDGHS 1679
Query: 479 VEA---PPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE- 534
+ + S+ E LP L++ ++ S A G Y+A + +
Sbjct: 1680 QHSRLLSSLSGSHTGESLP----LATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQC 1735
Query: 535 ---PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP--QWNETEPAC 589
P +YG S + VG V F C+ GY L QGS IEC+ QWN + P C
Sbjct: 1736 SSVPEPRYGKRLGSD--FSVGAIVRFECNSGYAL-QGSPEIECLPVPGALAQWNVSAPTC 1792
Query: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLD-IRVLRIGPGDVLTF 648
C G +T+ G +LSP +PEPY +C+W + V E I + + + D L
Sbjct: 1793 VVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEV 1852
Query: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
+DG D T +LG +SG L ++ + + F SD S G+ ++
Sbjct: 1853 FDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLE-----YKTVGLS 1907
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLT--WSEDLPSCQ 766
+CPE P +P+ + LV+ VV++QC PGY + G + + C W+ P C
Sbjct: 1908 SCPE-PAVPSNGVKTGERYLVN-DVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLC- 1964
Query: 767 RVTSCHDPGDVEHSRRLISSPKFP 790
+ C G VE +I SP FP
Sbjct: 1965 -IAQC--GGTVEEMEGVILSPGFP 1985
Score = 176 bits (445), Expect = 1e-43
Identities = 159/581 (27%), Positives = 239/581 (41%), Gaps = 33/581 (5%)
Query: 333 RFQSLPPPAGPGTFHFH--YQAY-LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQL 389
R S PP A + +AY L C P A G V + G S F C GYQL
Sbjct: 2096 RTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQL 2155
Query: 390 KGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEA 449
G LTC + T WD P C CGG I ++ G + SPGFP YS++ C WL+
Sbjct: 2156 TGHPVLTCQHGTNRNWDHPLPKCEVPCGGNI-TSSNGTVYSPGFPSPYSSSQDCVWLITV 2214
Query: 450 PEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVEL 509
P G + L+ + D + I +G AP + + + + SS ++
Sbjct: 2215 PIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRL--GVFTRSMAKKTVQSSSNQVLLKF 2272
Query: 510 STDSSGAAAGMALRYEAFQQGHCYEP-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQG 568
D++ A+ + A+ C P + + + +G V + C PG+TL G
Sbjct: 2273 HRDAATGGI-FAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTL-VG 2330
Query: 569 SIIIECVDPHDPQWNETEPACRAVCSGE--ITDSAGVVLSPNWPEPYGRGQDCIWGVHVE 626
+ I+ C Q+ P C C +TDS GV+LS ++P Y + Q C W V VE
Sbjct: 2331 NEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVE 2390
Query: 627 EDKRIMLDIR-VLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQFQS 684
D I L + L D +DG + +L SG S + TS ++ V +++ S
Sbjct: 2391 PDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSS 2450
Query: 685 DPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQV 744
D + ++GF I + + LP P Q G + + C GY++
Sbjct: 2451 DHAYN----RKGFKIRY-----SAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRL 2501
Query: 745 VGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICD 800
VG S+ +C Q WSE +P CQ + SC P ++ ++ ++ VG Y C
Sbjct: 2502 VGHSMAICTRHPQGYHLWSEAIPLCQAL-SCGLPEAPKNG--MVFGKEYTVGTKAMYSCS 2558
Query: 801 QGFVLMGSSILTCHDRQAGSPKWSDR--APKCLLEQLKPCHGLSAPENGARSPEKQLHPA 858
+G+ L + T G WS+R P+C+ +S R + +
Sbjct: 2559 EGYHLQAGAEATAECLDTG--LWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQF 2616
Query: 859 GATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
A + C PGY GQ I+C D P CR S
Sbjct: 2617 QAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIIS 2657
Score = 164 bits (416), Expect = 3e-40
Identities = 123/427 (28%), Positives = 189/427 (44%), Gaps = 25/427 (5%)
Query: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVCIA 414
C P P G + G S +F C GY L+G++ +TC+ + F W PVC A
Sbjct: 343 CPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRA 402
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQR-LHLHFEKVSLAEDDDRLII 473
+G I SP FP Y NN C W++ A + + L FE+ L D L +
Sbjct: 403 RMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTV 462
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKH-FFVELSTDSSGAAAGMALRYEAFQQGHC 532
+G + Y + + L+ S H ++ TD SG++ G YE +QG C
Sbjct: 463 GDGGQ-DGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSC 521
Query: 533 YEPFVK-YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
+P + YG S + G T++F C P + L G I C + QW+ +P C
Sbjct: 522 GDPGIPAYGRREGSR--FHHGDTLKFECQPAFELV-GQKAITC--QKNNQWSAKKPGCVF 576
Query: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
C T +GVVLSPN+PE YG C+W + + RI L + + P D L D
Sbjct: 577 SCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKD 636
Query: 651 GDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTC 710
G A VLG +SG + + +S ++FQ+D T G+ F R++ C
Sbjct: 637 GATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTF-----RHNEC 691
Query: 711 PELPEIP-NGWKSPSQPELVHGTVVTYQCYPGY-QVVGSSVLMC---QWDLTWSEDLPSC 765
P+ P +P NG + +L G+ +++ C G+ GS + C + + W+ + C
Sbjct: 692 PD-PGVPVNGKRFGDSLQL--GSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRC 748
Query: 766 QRVTSCH 772
+ H
Sbjct: 749 EAPCGGH 755
Score = 139 bits (351), Expect = 1e-32
Identities = 167/688 (24%), Positives = 268/688 (38%), Gaps = 66/688 (9%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
PC N + G++ SP SP DC + I+V G+GV + + + G+ +T+
Sbjct: 2181 PCGGNITSSNGTVYSP-GFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITI- 2238
Query: 302 GLGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCH 358
GP L + + + ++S ++Q L+F A G F + AY L C
Sbjct: 2239 -WDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHR--DAATGGIFAIAFSAYPLTKCP 2295
Query: 359 FPRRPAYGDVTVTS--LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
P +V + + G R+ C G+ L G LTC T ++ P+C C
Sbjct: 2296 PPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHC 2355
Query: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
+ +TG I+S +PG+Y TC WL+ + L E + D I +
Sbjct: 2356 PTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFD 2415
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
G + ++ P+ + Y + SS ++ S+D + G +RY A +C P
Sbjct: 2416 GPSGQS-PLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSA---PYCSLP 2471
Query: 536 FVK-YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAV- 592
+G T T P G ++ F C+ GY L S+ I P W+E P C+A+
Sbjct: 2472 RAPLHGFILGQTSTQP-GGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALS 2530
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVE---EDKRIMLDIRV---LRIGPGDVL 646
C G+V + C G H++ E LD + + P V
Sbjct: 2531 CGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCV- 2589
Query: 647 TFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQS------DPGTSVLGYQ------ 694
+T + S ++L + + QFQ+ DPG G +
Sbjct: 2590 ------PVTCPDVSSISVEHGRWRL---IFETQYQFQAQLMLICDPGYYYTGQRVIRCQA 2640
Query: 695 --QGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMC 752
+ + R +C ELP PNG + + V+G + C GY +VGS V C
Sbjct: 2641 NGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLS--VYGATAIFSCNSGYTLVGSRVREC 2698
Query: 753 QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILT 812
+ WS C C P + + I+ + +V Y C+ GF L+G S+
Sbjct: 2699 MANGLWSGSEVRC-LAGHCGTPEPIVNGH--INGENYSYRGSVVYQCNAGFRLIGMSVRI 2755
Query: 813 CHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVL 872
C WS + P C+L C +P + S + + GA + +SC L
Sbjct: 2756 CQQ----DHHWSGKTPFCVLVS---CGHPGSPPHSQMSGDS--YTVGAVVRYSCIGKRTL 2806
Query: 873 KGQASIKCVPGHPSHWSDPPPICRAASL 900
G ++ C G HW+ P C S+
Sbjct: 2807 VGNSTRMC--GLDGHWTGSLPHCSGTSV 2832
Score = 138 bits (348), Expect = 2e-32
Identities = 150/573 (26%), Positives = 238/573 (41%), Gaps = 65/573 (11%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGL 303
C++ GP G+++SP + +C + I+ + +++ Q+ +L E V
Sbjct: 26 CTFQLHGPNGTVESPGFPYGYPNYA-NCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFD 84
Query: 304 GGPDPLPLANQ--SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
G P P L + F L ++ + T +LR S + G FH Y+ +C P
Sbjct: 85 GPPQPENLRTRLTGFQLPATIVSAAT-TLSLRLISDYAVSAQG-FHATYEVLPSHTCGNP 142
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQ--PFWDSKEPVCIA--AC 416
R G ++ + G R+ C G+ L+G LTC ++ WD P C A AC
Sbjct: 143 GRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDAC 202
Query: 417 GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR-- 474
GG +R + G I SP FP Y NN C W + A G + L F L + D L +
Sbjct: 203 GGTLRGQS-GIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGT 261
Query: 475 -------NGDNVEAPPVYDSYEVEYLPIEGLLSSGKH-------------------FFVE 508
G ++ AP + +L + S G H V+
Sbjct: 262 EGSSLWFTGASLPAPVISSK---NWLRLH-FTSDGNHRQRGFSAQYQVKKQIELKSRGVK 317
Query: 509 LSTDSSGAAAGMALRYEAFQQGH--CYEPFV-KYGNFSSSTPTYPVGTTVEFSCDPGYTL 565
L + L QGH C +P + + G S + +G++V+F+C+ GY L
Sbjct: 318 LMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGS--DFRLGSSVQFTCNEGYDL 375
Query: 566 EQGSIIIECVDPHD--PQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRGQDCIWG 622
QGS I C+ D W++ P CRA +C + +G++ SPN+P Y C+W
Sbjct: 376 -QGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWI 434
Query: 623 V-HVEEDKRIMLDIRVLRIGPG-DVLTFYDG--DDLTARVLGQYSGPRSHFKLFTSMADV 678
+ + K I L + G D LT DG D VL +G + ++ +
Sbjct: 435 ITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQM 494
Query: 679 TIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQC 738
+ FQ+D S LG++ +E +C + P IP + HG + ++C
Sbjct: 495 WLLFQTDGSGSSLGFKAS-----YEEIEQGSCGD-PGIP-AYGRREGSRFHHGDTLKFEC 547
Query: 739 YPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSC 771
P +++VG + CQ + WS P C V SC
Sbjct: 548 QPAFELVGQKAITCQKNNQWSAKKPGC--VFSC 578
Score = 112 bits (279), Expect = 2e-24
Identities = 104/414 (25%), Positives = 167/414 (40%), Gaps = 57/414 (13%)
Query: 426 GRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVY 485
G + SPGFP Y N C W + A E R+ L F+ +L ED D L + +G PP
Sbjct: 35 GTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDG-----PPQP 89
Query: 486 DSYEVEYLPIE---GLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNF 542
++ + ++S+ + L +D + +A G YE C P + N
Sbjct: 90 ENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPG-RLPNG 148
Query: 543 SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV--DPHDPQWNETEPACRA--VCSGEIT 598
T+ +G V +SC+ G+ LE G ++ C + W+ P+CRA C G +
Sbjct: 149 IQQGSTFNLGDKVRYSCNLGFFLE-GHAVLTCHAGSENSATWDFPLPSCRADDACGGTLR 207
Query: 599 DSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARV 658
+G++ SP++P Y DC W + E I L ++ G YD ++T
Sbjct: 208 GQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDG-----YDFLEVTGTE 262
Query: 659 LGQ--YSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
++G + +S + + F SD G+ + + ++ +P
Sbjct: 263 GSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSK 322
Query: 717 PNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGD 776
N K+ +V+T VG S Q C DPG
Sbjct: 323 DNSQKT---------SVLTQ--------VGVS-----------------QGHNMCPDPGI 348
Query: 777 VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKC 830
E +RL S F +G++VQ+ C++G+ L GS +TC WSD P C
Sbjct: 349 PERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
Score = 100 bits (248), Expect = 9e-21
Identities = 137/569 (24%), Positives = 205/569 (36%), Gaps = 65/569 (11%)
Query: 354 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
++SC P G T G +A F C +GY L G+R C+ W E C+
Sbjct: 2655 IISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECM--ANGLWSGSEVRCL 2712
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDR--- 470
A G G I + S C+ L V + + D
Sbjct: 2713 AGHCGTPEPIVNGHINGENYSYRGSVVYQCN--------AGFRLIGMSVRICQQDHHWSG 2764
Query: 471 ----LIIRNGDNVEAPPVY----DSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAA---G 519
++ + + +PP DSY V + + GK V ST G G
Sbjct: 2765 KTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCI--GKRTLVGNSTRMCGLDGHWTG 2822
Query: 520 MALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHD 579
G C +P + P GT + FSC+ G+ L S E +
Sbjct: 2823 SLPHCSGTSVGVCGDPGIPAHGIRLGDSFDP-GTVMRFSCEAGHVLRGSS---ERTCQAN 2878
Query: 580 PQWNETEPACRAVCSGE--ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRV 637
W+ ++P C + G +A VV S +C G +
Sbjct: 2879 GSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATG---------- 2928
Query: 638 LRIGPGDVLTFYDGDDLTARVL--GQYSGPRSHFKLFTSMA-DVTIQFQSDPGTSVLGYQ 694
L V + G D V+ G P + +L + T+ +Q PG + ++
Sbjct: 2929 LLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHR 2988
Query: 695 QGFVIHFFEVPRNDT--------CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVG 746
+ + N T C P IPNG S + + G+ VTY C GYQ+
Sbjct: 2989 VSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGS--DFMWGSSVTYACLEGYQLSL 3046
Query: 747 SSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLM 806
+V C+ + +W+ +LP C V C DPG RR F ++V + C VL+
Sbjct: 3047 PAVFTCEGNGSWTGELPQCFPV-FCGDPGVPSRGRR--EDRGFSYRSSVSFSCHPPLVLV 3103
Query: 807 GSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSC 866
GS C WS P C+ L C P+ G ++ Q + G+T+ F C
Sbjct: 3104 GSPRRFCQ----SDGTWSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQVGSTVLFRC 3158
Query: 867 APGYVLKGQASIKCVPGHPSHWSDPPPIC 895
GY+L+G + C+P WS PP C
Sbjct: 3159 QKGYLLQGSTTRTCLPN--LTWSGTPPDC 3185
Score = 81.6 bits (200), Expect = 3e-15
Identities = 59/190 (31%), Positives = 88/190 (46%), Gaps = 16/190 (8%)
Query: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVTSCHDPGDVEHSRRLISSPKFPV 791
V++ C+P +VGS CQ D TWS PSC +T+C DPG + + +S + V
Sbjct: 3092 VSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQN-NSQGYQV 3150
Query: 792 GATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSP 851
G+TV + C +G++L GS+ TC + WS P C+ C P + A
Sbjct: 3151 GSTVLFRCQKGYLLQGSTTRTC----LPNLTWSGTPPDCVPHH---CRQPETPTH-ANVG 3202
Query: 852 EKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDV 911
L G T+ +SC G+ LKG + + S W+ PPIC G R ++
Sbjct: 3203 ALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGS-WTGKPPICLEVRPSG----RPINT 3257
Query: 912 AKAPAASSTL 921
A+ P + L
Sbjct: 3258 AREPPLTQAL 3267
Score = 49.7 bits (117), Expect = 1e-05
Identities = 55/210 (26%), Positives = 87/210 (41%), Gaps = 40/210 (19%)
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
SC DPG +++ R+ S K +G++V Y C G+ + G+S L+C G P W++ P
Sbjct: 1557 SCFDPGSIKNGTRVGSDLK--LGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPV 1614
Query: 830 CLLEQLKPCHGLSAPENG-ARSPE-KQLHPAG-ATIHFSCAP-GYVLKGQAS-------- 877
C PC G +G SP Q + +G ++F P YV+ GQ +
Sbjct: 1615 C----TAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALND 1670
Query: 878 -IKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVA 936
++ GH H +SL G + SL +A + A +A A
Sbjct: 1671 VVEVHDGHSQHSR------LLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPA------- 1717
Query: 937 MVLLVGGVYFYFSRLQGKSSLQ---LPRPR 963
G +F + + S+ Q +P PR
Sbjct: 1718 -----RGFHFVYQAVPRTSATQCSSVPEPR 1742
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 4/78 (5%)
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
+C +PG + + + S+ F +G V+Y C+ GF L G ++LTCH S W P
Sbjct: 138 TCGNPGRLPNGIQQGST--FNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPS 195
Query: 830 CLLEQLKPCHGLSAPENG 847
C + C G ++G
Sbjct: 196 CRADD--ACGGTLRGQSG 211
Score = 38.5 bits (88), Expect = 0.032
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 6/62 (9%)
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
SC DPG + RR +F G T+++ C F L+G +TC +WS + P
Sbjct: 520 SCGDPGIPAYGRR--EGSRFHHGDTLKFECQPAFELVGQKAITCQKNN----QWSAKKPG 573
Query: 830 CL 831
C+
Sbjct: 574 CV 575
Score = 38.1 bits (87), Expect = 0.041
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 4/66 (6%)
Query: 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPIC 895
C PE G R G+++ F+C GY L+G I C V + WSD P+C
Sbjct: 343 CPDPGIPERGKRLGSD--FRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVC 400
Query: 896 RAASLD 901
RA D
Sbjct: 401 RARMCD 406
Score = 32.0 bits (71), Expect = 3.0
Identities = 15/41 (36%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Query: 859 GATIHFSCAPGYVLKGQASIKCVPG--HPSHWSDPPPICRA 897
G + +SC G+ L+G A + C G + + W P P CRA
Sbjct: 158 GDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRA 198
Score = 31.6 bits (70), Expect = 3.9
Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 4/58 (6%)
Query: 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
C P G R + H G T+ F C P + L GQ +I C + WS P C
Sbjct: 521 CGDPGIPAYGRREGSRFHH--GDTLKFECQPAFELVGQKAITCQKN--NQWSAKKPGC 574
Score = 30.4 bits (67), Expect = 8.6
Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 5/62 (8%)
Query: 354 LLSCHFPRRPAYG-DVTVTSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPV 411
L +C P P +G G + F C GY L+G+ TCL N T W P
Sbjct: 3128 LTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLT---WSGTPPD 3184
Query: 412 CI 413
C+
Sbjct: 3185 CV 3186
>gi|157502199 CUB and Sushi multiple domains 1 [Homo sapiens]
Length = 3565
Score = 249 bits (637), Expect = 7e-66
Identities = 187/614 (30%), Positives = 287/614 (46%), Gaps = 37/614 (6%)
Query: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
G G+ ++T S G E T T + P P C + G EG+L S
Sbjct: 1059 GFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKGNEGTLLS 1118
Query: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPD----PLPLAN 313
P + S D +C + I G G+ ++ ++ L EG+T+ V G D PL
Sbjct: 1119 P-NFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKV--YDGKDSSSRPLGTFT 1175
Query: 314 QSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTS 372
++ LL G ++ S ++ L F + G F Y ++ L+ C P P YG
Sbjct: 1176 KNELL-GLILNSTSNHLWLEFNTNGSDTDQG-FQLTYTSFDLVKCEDPGIPNYGYRIRDE 1233
Query: 373 LHPGGSA-RFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSP 431
H + + C GY + G+ LTCL+ + WD P CIA CGG I AT+GRI+SP
Sbjct: 1234 GHFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSP 1293
Query: 432 GFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE 491
G+P Y NNL C W++EA G+ + LHF D L + +G V++ + +
Sbjct: 1294 GYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHDILKVWDGP-VDSDILLKEWSGS 1352
Query: 492 YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
LP E + S+ ++ +D + +G ++++ C +P + N + +
Sbjct: 1353 ALP-EDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQ-NGTRYGDSREA 1410
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRAVCSGEITDSAGVVLSPNWP 610
G TV F CDPGY L QG I CV ++ W P C A C G +T AGV+LSPN+P
Sbjct: 1411 GDTVTFQCDPGYQL-QGQAKITCVQLNNRFFWQPDPPTCIAACGGNLTGPAGVILSPNYP 1469
Query: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
+PY G++C W V V D I L + + P D L Y+G+D + ++G Y G ++
Sbjct: 1470 QPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYEGEDSNSPLIGSYQGSQAPE 1529
Query: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
++ +S + + F+SD + GF I F E PR + C + I NG + + +L
Sbjct: 1530 RIESSGNSLFLAFRSDASVGL----SGFAIEFKEKPR-EACFDPGNIMNGTRVGTDFKL- 1583
Query: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
G+ +TYQC GY+++ S + C +W + LPSC G S ++
Sbjct: 1584 -GSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCG----GQYTGSEGVVL 1638
Query: 786 SPKFPVGATVQYIC 799
SP +P T IC
Sbjct: 1639 SPNYPHNYTAGQIC 1652
Score = 232 bits (592), Expect = 1e-60
Identities = 188/707 (26%), Positives = 291/707 (41%), Gaps = 63/707 (8%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTVE 301
PCS NF+ G++ SP P L+C + I V G G++I+V + + + +++ +
Sbjct: 1802 PCSGNFTQRRGTILSP-GYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNWDSLEIH 1860
Query: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFP 360
G L + S ++ S ++Q L FQS A G FH Y+ L +C P
Sbjct: 1861 DGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAG-FHLEYKTVGLAACQEP 1919
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
P+ F C GY L+G H++C+ T W+ P+CIA CGG +
Sbjct: 1920 ALPSNSIKIGDRYMVNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSPLCIATCGGTL 1979
Query: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
+ G I+SPGFPG+Y NNL C W + P G H+ F S + D L I+NG
Sbjct: 1980 -STLGGVILSPGFPGSYPNNLDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGP-YH 2037
Query: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
P+ + LP LLS+ + +D S G L Y+A++ +C +P +
Sbjct: 2038 TSPMIGQFSGTDLP-AALLSTTHETLIHFYSDHSQNRQGFKLAYQAYELQNCPDP-PPFQ 2095
Query: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
N Y VG +V F C PGY L G ++ C + WN P C A C +T
Sbjct: 2096 NGYMINSDYSVGQSVSFECYPGYIL-IGHPVLTCQHGINRNWNYPFPRCDAPCGYNVTSQ 2154
Query: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTARVL 659
G + SP +P+ Y +DCIW + V + ++ +L+ D + +DG D + L
Sbjct: 2155 NGTIYSPGFPDEYPILKDCIWLITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQL 2214
Query: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
G +SG + ++S V ++F SD GF + F + C P +P
Sbjct: 2215 GVFSGNTALETAYSSTNQVLLKFHSDFSNG------GFFVLNFHAFQLKKCQPPPAVPQA 2268
Query: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQW--DLTWSEDLPSCQRVTSCHD---- 773
+ G V YQC+PGY +VG+ +L C+ L + LP+C+ ++
Sbjct: 2269 EMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTG 2328
Query: 774 ----------PGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAG-SP- 821
PG+ +S+ S K + D L D +G SP
Sbjct: 2329 SSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPL 2388
Query: 822 -----------------------KWS-DRAPK---CLLEQLKPCHGLSAPENGARSPEKQ 854
+WS D A + P L+ P +
Sbjct: 2389 LVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTHPLKNGGILNRT 2448
Query: 855 LHPAGATIHFSCAPGYVLKGQASIKC--VPGHPSHWSDPPPICRAAS 899
G+ +H+ C PGY + G ++ C P W P+C+A S
Sbjct: 2449 AGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAVS 2495
Score = 212 bits (539), Expect = 2e-54
Identities = 172/604 (28%), Positives = 263/604 (43%), Gaps = 83/604 (13%)
Query: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPF-WDSKEPVCIA 414
+C+ P P G S G + F C GYQL+G +TC+ F W P CIA
Sbjct: 1391 TCNDPGMPQNGTRYGDSREAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCIA 1450
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
ACGG + G I+SP +P Y C W ++ + L F+ ++ D L I
Sbjct: 1451 ACGGNL-TGPAGVILSPNYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIY 1509
Query: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE 534
G++ +P + SY+ P E + SSG F+ +D+S +G A+ ++ + C++
Sbjct: 1510 EGEDSNSPLI-GSYQGSQAP-ERIESSGNSLFLAFRSDASVGLSGFAIEFKEKPREACFD 1567
Query: 535 PFVKYGNFSSSTPT---YPVGTTVEFSCDPGYTLEQGSIIIECVDPHD--PQWNETEPAC 589
P GN + T + +G+T+ + CD GY + S I CV D P W++ P+C
Sbjct: 1568 P----GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSIT-CVIGADGKPSWDQVLPSC 1622
Query: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFY 649
A C G+ T S GVVLSPN+P Y GQ C++ + V ++ + + D+ +
Sbjct: 1623 NAPCGGQYTGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAELF 1682
Query: 650 DGDDLTARVLGQYSGPRSHFKL-FTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPR-N 707
DG AR+L SG S L + + ++F + G S +GF + VPR +
Sbjct: 1683 DGTHAQARLLSSLSGSHSGETLPLATSNQILLRFSAKSGASA----RGFHFVYQAVPRTS 1738
Query: 708 DT-CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD----LTWSEDL 762
DT C +PE G + S E G++V ++C PGY + GS+ L CQ W++ +
Sbjct: 1739 DTQCSSVPEPRYGRRIGS--EFSAGSIVRFECNPGYLLQGSTALHCQSVPNALAQWNDTI 1796
Query: 763 PSCQRVTSCHDPGDVEHSRRLISSPKF--PVGATVQYICDQGFVLMGSSI---------- 810
PSC V C G+ R I SP + P G + I + V GS I
Sbjct: 1797 PSC--VVPCS--GNFTQRRGTILSPGYPEPYGNNLNCIW-KIIVTEGSGIQIQVISFATE 1851
Query: 811 -----LTCHDR-QAGSPK---WSDRAPKCLLEQ--------------------------- 834
L HD +P+ +S LL
Sbjct: 1852 QNWDSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLEYKTV 1911
Query: 835 -LKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPP 893
L C + P N + ++ + + F C PGY L+G++ I C+PG W+ P P
Sbjct: 1912 GLAACQEPALPSNSIKIGDRYM--VNDVLSFQCEPGYTLQGRSHISCMPGTVRRWNYPSP 1969
Query: 894 ICRA 897
+C A
Sbjct: 1970 LCIA 1973
Score = 199 bits (505), Expect = 1e-50
Identities = 153/556 (27%), Positives = 247/556 (44%), Gaps = 28/556 (5%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTVEG 302
C N GP G + SP D + + P +++ + L G +T+TV
Sbjct: 412 CGSNLRGPSGVITSPNYPVQYEDNAHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGD 471
Query: 303 LGGPDPLPLANQSFLLRGQ----VIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
G + ++L G +I S ++Q L QS PG + + C
Sbjct: 472 AGKVGDT--RSVLYVLTGSSVPDLIVSMSNQMWLHLQSDDSIGSPGFKAVYQEIEKGGCG 529
Query: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGG 418
P PAYG T +S G + F C ++L G R +TC Q W +P C+ +C
Sbjct: 530 DPGIPAYGKRTGSSFLHGDTLTFECPAAFELVGERVITCQQNNQ--WSGNKPSCVFSCFF 587
Query: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
A++G I+SP +P Y NN+ C WL+ + G R+HL F + D L +++ D
Sbjct: 588 NF-TASSGIILSPNYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAVKD-DG 645
Query: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK 538
+ V ++ +P + L SSG +E +D S G + Y F Q C++P +
Sbjct: 646 ISDITVLGTFSGNEVPSQ-LASSGHIVRLEFQSDHSTTGRGFNITYTTFGQNECHDPGIP 704
Query: 539 YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSGEI 597
N + +G++V F CD G+ QGS I C+ + W+ T P C A C G +
Sbjct: 705 I-NGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHL 763
Query: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTA 656
T S+GV+L P WP Y C W + + I + + D L DG ++
Sbjct: 764 TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGPASSS 823
Query: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVP-RNDTCPELPE 715
++G+Y G ++ L ++ + + F +D S + GF+IH+ V +D+C + P
Sbjct: 824 PLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSI----GFLIHYESVTLESDSCLD-PG 878
Query: 716 IP-NGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
IP NG + + + VT+ C PGY + L+C+ + W+ LPSC +
Sbjct: 879 IPVNGHRHGG--DFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCG---- 932
Query: 775 GDVEHSRRLISSPKFP 790
G ++ + SP FP
Sbjct: 933 GYIQGKSGTVLSPGFP 948
Score = 188 bits (478), Expect = 2e-47
Identities = 186/716 (25%), Positives = 292/716 (40%), Gaps = 86/716 (12%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVG--LDCFFYISVYPGYGVEIKVQNISLR-EGETVTV 300
C +NF+ G + SP + P + G ++C + I PG + + + + + + + V
Sbjct: 585 CFFNFTASSGIILSP---NYPEEYGNNMNCVWLIISEPGSRIHLIFNDFDVEPQFDFLAV 641
Query: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHF 359
+ G D L S + S H L FQS G G F+ Y + + CH
Sbjct: 642 KDDGISDITVLGTFSGNEVPSQLASSGHIVRLEFQSDHSTTGRG-FNITYTTFGQNECHD 700
Query: 360 PRRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACG 417
P P G G S FHC G+ + +G+ +TC L W S P C A CG
Sbjct: 701 PGIPINGRRFGDRFLLGSSVSFHCDDGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCG 760
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
G + A++G I+ PG+PG Y ++L C W++EA G + + F++ + D L +R+G
Sbjct: 761 GHL-TASSGVILPPGWPGYYKDSLHCEWIIEAKPGHSIKITFDRFQTEVNYDTLEVRDGP 819
Query: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEA--FQQGHCYEP 535
+ P+ Y P + L+S+G ++ +TD+S ++ G + YE+ + C +P
Sbjct: 820 -ASSSPLIGEYHGTQAP-QFLISTGNFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDP 877
Query: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSG 595
+ N + + +TV FSCDPGYTL ++ C H QWN P+C A+C G
Sbjct: 878 GIPV-NGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLV-CERNH--QWNHALPSCDALCGG 933
Query: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGD--VLTFYDG-- 651
I +G VLSP +P+ Y +C W + V K + + + +L DG
Sbjct: 934 YIQGKSGTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSF 993
Query: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
+ AR+ G LF + ++F SD S +GF I F E + C
Sbjct: 994 SEPVARLTGSVLPHTIKAGLFGNFT-AQLRFISDFSIS----YEGFNITFSEYDL-EPCD 1047
Query: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVT 769
+ P +P + G +T+ C+ GY++ G++ L C WS LP C V
Sbjct: 1048 D-PGVP-AFSRRIGFHFGVGDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRC--VA 1103
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYIC---------------DQGFVLMGSSILTCH 814
C V+ + + SP FP + C + F L L +
Sbjct: 1104 EC--GASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
Query: 815 DRQAGSPK----------------------W-------SDRAPKCLLE----QLKPCHGL 841
D + S + W SD L L C
Sbjct: 1162 DGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDP 1221
Query: 842 SAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
P G R ++ H + +SC PGY + G ++ C+ G W P P C A
Sbjct: 1222 GIPNYGYRIRDEG-HFTDTVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSCIA 1276
Score = 187 bits (474), Expect = 6e-47
Identities = 179/652 (27%), Positives = 271/652 (41%), Gaps = 49/652 (7%)
Query: 269 LDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQ-SFLLRGQVIRSPT 327
LDC + IS+ GYG I+ N S G P+ Q S + S T
Sbjct: 1999 LDCTWRISLPIGYGAHIQFLNFSTEANHDFLEIQNGPYHTSPMIGQFSGTDLPAALLSTT 2058
Query: 328 HQAALRFQSLPPPAGPGTFHFHYQAY-LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATG 386
H+ + F S G F YQAY L +C P G + + G S F C G
Sbjct: 2059 HETLIHFYSDHSQNRQG-FKLAYQAYELQNCPDPPPFQNGYMINSDYSVGQSVSFECYPG 2117
Query: 387 YQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWL 446
Y L G LTC + W+ P C A CG + + G I SPGFP Y C WL
Sbjct: 2118 YILIGHPVLTCQHGINRNWNYPFPRCDAPCGYNV-TSQNGTIYSPGFPDEYPILKDCIWL 2176
Query: 447 LEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFF 506
+ P G ++++F + +D + + +G + +P + +E SS
Sbjct: 2177 ITVPPGHGVYINFTLLQTEAVNDYIAVWDGPDQNSPQL--GVFSGNTALETAYSSTNQVL 2234
Query: 507 VELSTDSSGAAAGMALRYEAFQQGHCYEP-FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL 565
++ +D S L + AFQ C P V + + +G V++ C PGYTL
Sbjct: 2235 LKFHSDFSNGGF-FVLNFHAFQLKKCQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTL 2293
Query: 566 EQGSIIIECVDPHDPQWNETEPACRAVC-SGEI-TDSAGVVLSPNWPEPYGRGQDCIWGV 623
G+ I+ C Q+ + P C A C + E+ T S+GV+LSP +P Y Q C W +
Sbjct: 2294 V-GTDILTCKLSSQLQFEGSLPTCEAQCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSI 2352
Query: 624 HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQ 681
VE + I + + + D L +DG + +L SG + FTS ++ + ++
Sbjct: 2353 KVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSNQLYLR 2412
Query: 682 FQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPG 741
+ +D TS G++ + + C + NG V G+ V Y C PG
Sbjct: 2413 WSTDHATSKKGFKIRYAAPY--------CSLTHPLKNGGILNRTAGAV-GSKVHYFCKPG 2463
Query: 742 YQVVGSSVLMCQWD----LTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQY 797
Y++VG S C+ + W P CQ V SC P + + +F + + V Y
Sbjct: 2464 YRMVGHSNATCRRNPLGMYQWDSLTPLCQAV-SCGIPESPGNGS--FTGNEFTLDSKVVY 2520
Query: 798 ICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKP--CHGLSAPENGARSPEK-- 853
C +GF L S T ++ G WS++ KP C ++ P A+ E
Sbjct: 2521 ECHEGFKLESSQQATAVCQEDG--LWSNKG--------KPPTCKPVACPSIEAQLSEHVI 2570
Query: 854 ------QLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
L+ GA + SC+PGY L+G ++C + D P CR S
Sbjct: 2571 WRLVSGSLNEYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVIS 2622
Score = 179 bits (454), Expect = 1e-44
Identities = 191/722 (26%), Positives = 286/722 (39%), Gaps = 80/722 (11%)
Query: 236 TTVQTPGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG 295
T + PC + + G + P D L C + I PG+ ++I E
Sbjct: 751 TVPRCEAPCGGHLTASSGVILPPGWPGYYKD-SLHCEWIIEAKPGHSIKITFDRFQT-EV 808
Query: 296 ETVTVEGLGGP-DPLPLANQSFLLRG-QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAY 353
T+E GP PL + + Q + S + L F + + G F HY++
Sbjct: 809 NYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTGNFMYLLFTTDNSRSSIG-FLIHYESV 867
Query: 354 LL---SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEP 410
L SC P P G + F C GY L L C Q W+ P
Sbjct: 868 TLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQ--WNHALP 925
Query: 411 VCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDR 470
C A CGG I+ + G ++SPGFP Y N+L C W +E G+ + + F L D
Sbjct: 926 SCDALCGGYIQGKS-GTVLSPGFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDY 984
Query: 471 LIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
L+I + P + V I+ L + +D S + G + + +
Sbjct: 985 LLITEDGSFSEPVARLTGSVLPHTIKAGLFGNFTAQLRFISDFSISYEGFNITFSEYDLE 1044
Query: 531 HCYEPFVKYGNFSSSTPT-YPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
C +P V FS + VG ++ FSC GY LE G+ + C+ W+ P C
Sbjct: 1045 PCDDPGVPA--FSRRIGFHFGVGDSLTFSCFLGYRLE-GATKLTCLGGGRRVWSAPLPRC 1101
Query: 590 RAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFY 649
A C + + G +LSPN+P Y +CI+ + E K I L R ++ GD L Y
Sbjct: 1102 VAECGASVKGNEGTLLSPNFPSNYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDTLKVY 1161
Query: 650 DGDDLTARVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
DG D ++R LG ++ + S ++ + ++F ++ + G+Q + F++ +
Sbjct: 1162 DGKDSSSRPLGTFTKNELLGLILNSTSNHLWLEFNTNGSDTDQGFQLTYTS--FDLVK-- 1217
Query: 709 TCPELPEIPN-GWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
C + P IPN G++ + TVV Y C PGY + GS+ L C W + LPSC
Sbjct: 1218 -CED-PGIPNYGYRIRDEGHFTD-TVVLYSCNPGYAMHGSNTLTCLSGDRRVWDKPLPSC 1274
Query: 766 QRVTSCHDPGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----------MGSS 809
+ C S R++S P +P C D G + M
Sbjct: 1275 --IAECGGQIHAATSGRILS-PGYPAPYDNNLHCTWIIEADPGKTISLHFIVFDTEMAHD 1331
Query: 810 ILTCHDRQAGSP----KWSDRA-PKCLLEQLKP--------------------------- 837
IL D S +WS A P+ +
Sbjct: 1332 ILKVWDGPVDSDILLKEWSGSALPEDIHSTFNSLTLQFDSDFFISKSGFSIQFSTSIAAT 1391
Query: 838 CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVP-GHPSHWSDPPPICR 896
C+ P+NG R + + AG T+ F C PGY L+GQA I CV + W PP C
Sbjct: 1392 CNDPGMPQNGTRYGDSR--EAGDTVTFQCDPGYQLQGQAKITCVQLNNRFFWQPDPPTCI 1449
Query: 897 AA 898
AA
Sbjct: 1450 AA 1451
Score = 164 bits (416), Expect = 3e-40
Identities = 149/567 (26%), Positives = 239/567 (42%), Gaps = 46/567 (8%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
C N +GP G + SP + P G +C + + V P + + + ++ ++ E
Sbjct: 1452 CGGNLTGPAGVILSP-NYPQPYPPGKECDWRVKVNPDFVIALIFKSFNMEPSYDFLHIYE 1510
Query: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
G PL + + + I S + L F+S G F ++ +C P
Sbjct: 1511 GEDSNSPL-IGSYQGSQAPERIESSGNSLFLAFRS-DASVGLSGFAIEFKEKPREACFDP 1568
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACGG 418
G T G + + C +GY++ +TC+ +P WD P C A CGG
Sbjct: 1569 GNIMNGTRVGTDFKLGSTITYQCDSGYKILDPSSITCVIGADGKPSWDQVLPSCNAPCGG 1628
Query: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLII 473
+ G ++SP +P NY+ C + + P+ GQ + LAE +
Sbjct: 1629 QY-TGSEGVVLSPNYPHNYTAGQICLYSITVPKEFVVFGQFAYFQTALNDLAE------L 1681
Query: 474 RNGDNVEA---PPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
+G + +A + S+ E LP L++ + S S +A G Y+A +
Sbjct: 1682 FDGTHAQARLLSSLSGSHSGETLP----LATSNQILLRFSAKSGASARGFHFVYQAVPRT 1737
Query: 531 HCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP--QWNE 584
+ P +YG S + G+ V F C+PGY L QGS + C + QWN+
Sbjct: 1738 SDTQCSSVPEPRYGRRIGSE--FSAGSIVRFECNPGYLL-QGSTALHCQSVPNALAQWND 1794
Query: 585 TEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG- 643
T P+C CSG T G +LSP +PEPYG +CIW + V E I + +
Sbjct: 1795 TIPSCVVPCSGNFTQRRGTILSPGYPEPYGNNLNCIWKIIVTEGSGIQIQVISFATEQNW 1854
Query: 644 DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFE 703
D L +DG D+TA LG +SG L ++ + + FQSD + G+ ++
Sbjct: 1855 DSLEIHDGGDVTAPRLGSFSGTTVPALLNSTSNQLYLHFQSDISVAAAGFHLE-----YK 1909
Query: 704 VPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLP 763
C E P +P+ +V+ V+++QC PGY + G S + C + P
Sbjct: 1910 TVGLAACQE-PALPSNSIKIGDRYMVN-DVLSFQCEPGYTLQGRSHISCMPGTVRRWNYP 1967
Query: 764 SCQRVTSCHDPGDVEHSRRLISSPKFP 790
S + +C G + +I SP FP
Sbjct: 1968 SPLCIATC--GGTLSTLGGVILSPGFP 1992
Score = 158 bits (400), Expect = 2e-38
Identities = 170/672 (25%), Positives = 254/672 (37%), Gaps = 98/672 (14%)
Query: 203 GAGIGIQGTITSSTASG---DDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPT 259
G GI+ T+T S G D+E C G G++ SP
Sbjct: 887 GGDFGIRSTVTFSCDPGYTLSDDEPLVCERNHQWNHALPSCDALCGGYIQGKSGTVLSP- 945
Query: 260 DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLR 319
L+C + I V G GV++ L + G P+A + +
Sbjct: 946 GFPDFYPNSLNCTWTIEVSHGKGVQMIFHTFHLESSHDYLLITEDGSFSEPVARLTGSVL 1005
Query: 320 GQVIRSP---THQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
I++ A LRF S + G F+ + Y L C P PA+
Sbjct: 1006 PHTIKAGLFGNFTAQLRFISDFSISYEG-FNITFSEYDLEPCDDPGVPAFSRRIGFHFGV 1064
Query: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
G S F C GY+L+GA LTCL + W + P C+A CG ++ G ++SP FP
Sbjct: 1065 GDSLTFSCFLGYRLEGATKLTCLGGGRRVWSAPLPRCVAECGASVKG-NEGTLLSPNFPS 1123
Query: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
NY NN C + +E G+ +HL L E D L + +G + + P+ + E L +
Sbjct: 1124 NYDNNHECIYKIETEAGKGIHLRTRSFQLFEGDT-LKVYDGKDSSSRPLGTFTKNELLGL 1182
Query: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTV 555
L S+ H ++E +T+ S G L Y +F C +P + + + T V
Sbjct: 1183 I-LNSTSNHLWLEFNTNGSDTDQGFQLTYTSFDLVKCEDPGIPNYGYRIRDEGHFTDTVV 1241
Query: 556 EFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEI-TDSAGVVLSPNWPEPYG 614
+SC+PGY + GS + C+ W++ P+C A C G+I ++G +LSP +P PY
Sbjct: 1242 LYSCNPGYAMH-GSNTLTCLSGDRRVWDKPLPSCIAECGGQIHAATSGRILSPGYPAPYD 1300
Query: 615 RGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLF-T 673
C W + + K I L HF +F T
Sbjct: 1301 NNLHCTWIIEADPGKTISL----------------------------------HFIVFDT 1326
Query: 674 SMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTV 733
MA ++ P S + ++ W + PE +H T
Sbjct: 1327 EMAHDILKVWDGPVDSDILLKE------------------------WSGSALPEDIHSTF 1362
Query: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTS----CHDPGDVEHSRRLISSPKF 789
S L D S+ S Q TS C+DPG ++ R S +
Sbjct: 1363 ------------NSLTLQFDSDFFISKSGFSIQFSTSIAATCNDPGMPQNGTRYGDSRE- 1409
Query: 790 PVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG-LSAPENGA 848
G TV + CD G+ L G + +TC W P C + C G L+ P
Sbjct: 1410 -AGDTVTFQCDPGYQLQGQAKITCVQLN-NRFFWQPDPPTC----IAACGGNLTGPAGVI 1463
Query: 849 RSPE-KQLHPAG 859
SP Q +P G
Sbjct: 1464 LSPNYPQPYPPG 1475
Score = 155 bits (391), Expect = 2e-37
Identities = 182/749 (24%), Positives = 289/749 (38%), Gaps = 118/749 (15%)
Query: 242 GPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREG-ETVTV 300
G C G S+ SP S + DC + I PG + + + L EG + + +
Sbjct: 206 GACGGTLRGTSSSISSP-HFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLEI 264
Query: 301 EGLGGPD--------PLPLANQSFLLRGQVIRSPTHQA-----------ALRFQSLPPPA 341
G P P P+ + LR H+ A+ +S
Sbjct: 265 SGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKSRGVKM 324
Query: 342 GPGTFHFHYQAYLLS---------CHFPRRPAYGDVTVTSL-HPGGSARFHCATGYQLKG 391
P H + L C P P G + G + +F C Y L+G
Sbjct: 325 LPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSCEDNYVLQG 384
Query: 392 ARHLTCLNATQPF--WDSKEPVCIA-ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLE 448
++ +TC T+ W P+C A CG +R + G I SP +P Y +N C W++
Sbjct: 385 SKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPS-GVITSPNYPVQYEDNAHCVWVIT 443
Query: 449 APEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEG-----LLSSG 502
+ + + L FE+ L D L + GD A V D+ V Y+ ++S
Sbjct: 444 TTDPDKVIKLAFEEFELERGYDTLTV--GD---AGKVGDTRSVLYVLTGSSVPDLIVSMS 498
Query: 503 KHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVK-YGNFSSSTPTYPVGTTVEFSCDP 561
++ L +D S + G Y+ ++G C +P + YG + S+ + G T+ F C
Sbjct: 499 NQMWLHLQSDDSIGSPGFKAVYQEIEKGGCGDPGIPAYGKRTGSSFLH--GDTLTFECPA 556
Query: 562 GYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIW 621
+ L G +I C + QW+ +P+C C T S+G++LSPN+PE YG +C+W
Sbjct: 557 AFELV-GERVITC--QQNNQWSGNKPSCVFSCFFNFTASSGIILSPNYPEEYGNNMNCVW 613
Query: 622 GVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTI 680
+ E RI L + P D L D VLG +SG +L +S V +
Sbjct: 614 LIISEPGSRIHLIFNDFDVEPQFDFLAVKDDGISDITVLGTFSGNEVPSQLASSGHIVRL 673
Query: 681 QFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIP-NGWKSPSQPELVHGTVVTYQCY 739
+FQSD T+ +GF I + +N+ C + P IP NG + + + G+ V++ C
Sbjct: 674 EFQSDHSTT----GRGFNITYTTFGQNE-CHD-PGIPINGRRFGDR--FLLGSSVSFHCD 725
Query: 740 PGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSCH---------DPG------DVEHS 780
G+ + GS + C ++ WS +P C+ H PG D H
Sbjct: 726 DGFVKTQGSESITCILQDGNVVWSSTVPRCEAPCGGHLTASSGVILPPGWPGYYKDSLHC 785
Query: 781 RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPK-----WSDRAPKCLLEQL 835
+I + G +++ D+ + L D A S +AP+ L+
Sbjct: 786 EWIIEAKP---GHSIKITFDRFQTEVNYDTLEVRDGPASSSPLIGEYHGTQAPQFLISTG 842
Query: 836 KPCHGLSAPENGARSPEKQLHPAG---------------------------ATIHFSCAP 868
+ L +N S +H +T+ FSC P
Sbjct: 843 NFMYLLFTTDNSRSSIGFLIHYESVTLESDSCLDPGIPVNGHRHGGDFGIRSTVTFSCDP 902
Query: 869 GYVLKGQASIKCVPGHPSHWSDPPPICRA 897
GY L + C H W+ P C A
Sbjct: 903 GYTLSDDEPLVCERNH--QWNHALPSCDA 929
Score = 135 bits (340), Expect = 2e-31
Identities = 130/478 (27%), Positives = 194/478 (40%), Gaps = 62/478 (12%)
Query: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNA--TQPFWDSKEPVCI 413
+C P G + T + G R+ C GY L+G LTC+ + WD P C
Sbjct: 144 TCGNPGEILKGVLHGTRFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
Query: 414 A--ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
A ACGG +R T+ I SP FP Y NN C W + A G + L F L E D L
Sbjct: 204 AEGACGGTLRG-TSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFL 262
Query: 472 IIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYE------ 525
I EAP ++ + P+ +SS + ++DS+ G +++
Sbjct: 263 EI---SGTEAPSIWLTGMNLPSPV---ISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIE 316
Query: 526 --------------------------AFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSC 559
A C +P + + + VG V+FSC
Sbjct: 317 LKSRGVKMLPSKDGSHKNSVLSQGGVALVSDMCPDPGIPENGRRAGSDFSRVGANVQFSC 376
Query: 560 DPGYTLEQGSIIIEC--VDPHDPQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRG 616
+ Y L QGS I C V W++ P CRA C + +GV+ SPN+P Y
Sbjct: 377 EDNYVL-QGSKSITCQRVTETLAAWSDHRPICRARTCGSNLRGPSGVITSPNYPVQYEDN 435
Query: 617 QDCIWGV-HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL--TARVLGQYSGPRSHFKLF 672
C+W + + DK I L + G D LT D + T VL +G +
Sbjct: 436 AHCVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIV 495
Query: 673 TSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGT 732
+ + + QSD GF + E+ + C + P IP + + +HG
Sbjct: 496 SMSNQMWLHLQSDDSIG----SPGFKAVYQEIEKGG-CGD-PGIP-AYGKRTGSSFLHGD 548
Query: 733 VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
+T++C +++VG V+ CQ + WS + PSC V SC + S +I SP +P
Sbjct: 549 TLTFECPAAFELVGERVITCQQNNQWSGNKPSC--VFSCF--FNFTASSGIILSPNYP 602
Score = 114 bits (286), Expect = 3e-25
Identities = 147/573 (25%), Positives = 222/573 (38%), Gaps = 116/573 (20%)
Query: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
CGG+++ G I SPGFP Y N C W++ E R+ L F +L ED D L + +
Sbjct: 32 CGGLVQGPN-GTIESPGFPHGYPNYANCTWIIITGERNRIQLSFHTFALEEDFDILSVYD 90
Query: 476 GDNVEAPPVYDSYEVE----YLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGH 531
G P + +V LP ++S+G + +TD + +A G YE
Sbjct: 91 GQ-----PQQGNLKVRLSGFQLP-SSIVSTGSILTLWFTTDFAVSAQGFKALYEVLPSHT 144
Query: 532 CYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDP-HDPQWNETEPACR 590
C P T + +G + +SC PGY LE +I+ V P + W+ P CR
Sbjct: 145 CGNPGEILKGVLHGT-RFNIGDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCR 203
Query: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVL- 646
A C G + ++ + SP++P Y DC W + E I L ++ G D L
Sbjct: 204 AEGACGGTLRGTSSSISSPHFPSEYENNADCTWTILAEPGDTIALVFTDFQLEEGYDFLE 263
Query: 647 --------TFYDGDDLTARVLGQYSGPRSHF--------KLFTSMADV--TIQFQSDPGT 688
+ G +L + V+ + R HF K F + V I+ +S G
Sbjct: 264 ISGTEAPSIWLTGMNLPSPVISSKNWLRLHFTSDSNHRRKGFNAQFQVKKAIELKS-RGV 322
Query: 689 SVL----GYQQGFVIHFFEVPR-NDTCPELPEIP-NGWKSPSQPELVHGTVVTYQCYPGY 742
+L G + V+ V +D CP+ P IP NG ++ S V G V + C Y
Sbjct: 323 KMLPSKDGSHKNSVLSQGGVALVSDMCPD-PGIPENGRRAGSDFSRV-GANVQFSCEDNY 380
Query: 743 QVVGSSVLMCQ----WDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPV------- 791
+ GS + CQ WS+ P C R +C ++ +I+SP +PV
Sbjct: 381 VLQGSKSITCQRVTETLAAWSDHRPIC-RARTC--GSNLRGPSGVITSPNYPVQYEDNAH 437
Query: 792 -------------------------GATVQYICDQG---------FVLMGSSI------- 810
G + D G +VL GSS+
Sbjct: 438 CVWVITTTDPDKVIKLAFEEFELERGYDTLTVGDAGKVGDTRSVLYVLTGSSVPDLIVSM 497
Query: 811 ---LTCH---DRQAGSPKWSDRAPKCLLEQLKP--CHGLSAPENGARSPEKQLHPAGATI 862
+ H D GSP + K + ++++ C P G R+ LH G T+
Sbjct: 498 SNQMWLHLQSDDSIGSPGF-----KAVYQEIEKGGCGDPGIPAYGKRTGSSFLH--GDTL 550
Query: 863 HFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
F C + L G+ I C + WS P C
Sbjct: 551 TFECPAAFELVGERVITCQQN--NQWSGNKPSC 581
Score = 105 bits (261), Expect = 3e-22
Identities = 98/370 (26%), Positives = 157/370 (42%), Gaps = 22/370 (5%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--V 300
PC +N + G++ SP + DC + I+V PG+GV I N +L + E V +
Sbjct: 2146 PCGYNVTSQNGTIYSP-GFPDEYPILKDCIWLITVPPGHGVYI---NFTLLQTEAVNDYI 2201
Query: 301 EGLGGPDPLPLANQSFLLRG----QVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS 356
GPD + Q + G + S T+Q L+F S G +FH L
Sbjct: 2202 AVWDGPDQN--SPQLGVFSGNTALETAYSSTNQVLLKFHSDFSNGGFFVLNFH-AFQLKK 2258
Query: 357 CHFPRRPAYGDVTVTS--LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIA 414
C P ++ G ++ C GY L G LTC ++Q ++ P C A
Sbjct: 2259 CQPPPAVPQAEMLTEDDDFEIGDFVKYQCHPGYTLVGTDILTCKLSSQLQFEGSLPTCEA 2318
Query: 415 AC-GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
C +R ++G I+SPG+PGNY N+ TC W ++ + + + + D L +
Sbjct: 2319 QCPANEVRTGSSGVILSPGYPGNYFNSQTCSWSIKVEPNYNITIFVDTFQSEKQFDALEV 2378
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
+G + ++ P+ + S ++ STD + + G +RY A +
Sbjct: 2379 FDGSSGQS-PLLVVLSGNHTEQSNFTSRSNQLYLRWSTDHATSKKGFKIRYAAPYCSLTH 2437
Query: 534 EPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP-QWNETEPACRAV 592
+K G + T VG+ V + C PGY + S +P QW+ P C+AV
Sbjct: 2438 P--LKNGGILNRT-AGAVGSKVHYFCKPGYRMVGHSNATCRRNPLGMYQWDSLTPLCQAV 2494
Query: 593 CSGEITDSAG 602
G I +S G
Sbjct: 2495 SCG-IPESPG 2503
Score = 105 bits (261), Expect = 3e-22
Identities = 157/651 (24%), Positives = 236/651 (36%), Gaps = 111/651 (17%)
Query: 271 CFFYISVYPGYGVEIKVQNI-SLREGETVTV-EGLGGPDPLPLANQSFLLRGQVIRSPTH 328
C + I V P Y + I V S ++ + + V +G G PL + S ++
Sbjct: 2348 CSWSIKVEPNYNITIFVDTFQSEKQFDALEVFDGSSGQSPLLVVLSGNHTEQSNFTSRSN 2407
Query: 329 QAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQ 388
Q LR+ + + G F Y A S P + G + T+ G + C GY+
Sbjct: 2408 QLYLRWSTDHATSKKG-FKIRYAAPYCSLTHPLKNG-GILNRTAGAVGSKVHYFCKPGYR 2465
Query: 389 LKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWL 446
+ G + TC WDS P+C A G+ + G F + CH
Sbjct: 2466 MVGHSNATCRRNPLGMYQWDSLTPLCQAVSCGIPESPGNGSFTGNEFTLDSKVVYECH-- 2523
Query: 447 LEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVE------YLPIEG--- 497
EG +L + ++ ++D + P S E + + + G
Sbjct: 2524 ----EGFKLESSQQATAVCQEDGLWSNKGKPPTCKPVACPSIEAQLSEHVIWRLVSGSLN 2579
Query: 498 ------LLSSGKHFFVE---LSTDSSGAAAGMALRYEAFQQGHCYE-PFVKYGNFSSSTP 547
LLS +++E L + + + + C F GN +
Sbjct: 2580 EYGAQVLLSCSPGYYLEGWRLLRCQANGTWNIGDERPSCRVISCGSLSFPPNGNKIGTLT 2639
Query: 548 TYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSP 607
Y G T F+C+ GYTL GS + EC+ + W+ +E C A G
Sbjct: 2640 VY--GATAIFTCNTGYTLV-GSHVRECLA--NGLWSGSETRCLAGHCGS----------- 2683
Query: 608 NWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRS 667
P+P G H+ D D V + PG
Sbjct: 2684 --PDPIVNG-------HISGDGFSYRDTVVYQCNPG------------------------ 2710
Query: 668 HFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPE 727
F+L + + +Q G + + VP TC +G+ + S+
Sbjct: 2711 -FRLVGTSVRICLQDHKWSGQTPVC-----------VPI--TCGHPGNPAHGFTNGSEFN 2756
Query: 728 LVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISS- 786
L VV + C GY + G S C+ + WS LP+C RV +C DPG VE++ R
Sbjct: 2757 L--NDVVNFTCNTGYLLQGVSRAQCRSNGQWSSPLPTC-RVVNCSDPGFVENAIRHGQQN 2813
Query: 787 --PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAP 844
F G ++ Y C +GF L+GSS LTC + W PKCL C P
Sbjct: 2814 FPESFEYGMSILYHCKKGFYLLGSSALTC----MANGLWDRSLPKCLAIS---CGHPGVP 2866
Query: 845 ENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
N + E L GA +H+SC L G + C SHWS P C
Sbjct: 2867 ANAVLTGE--LFTYGAVVHYSCRGSESLIGNDTRVC--QEDSHWSGALPHC 2913
Score = 87.0 bits (214), Expect = 8e-17
Identities = 127/550 (23%), Positives = 185/550 (33%), Gaps = 146/550 (26%)
Query: 357 CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIA-A 415
C P PA+G RF C G+QL+G+ TCL W +PVC A +
Sbjct: 2921 CGDPGTPAHGSRLGDDFKTKSLLRFSCEMGHQLRGSPERTCL--LNGSWSGLQPVCEAVS 2978
Query: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
CG +PG P N
Sbjct: 2979 CG------------NPGTP---------------------------------------TN 2987
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
G V + + S V Y EG +SG + ++G G A C +P
Sbjct: 2988 GMIVSSDGILFSSSVIYACWEGYKTSG---LMTRHCTANGTWTGTAPDCTIIS---CGDP 3041
Query: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQ-GSIIIECVDPHDPQWNETEPACRAVCS 594
T + TV + C+PGY +E S I C D +WN ++P C+A
Sbjct: 3042 GTLANGIQFGTD-FTFNKTVSYQCNPGYVMEAVTSATIRCTK--DGRWNPSKPVCKA--- 3095
Query: 595 GEITDSAGVVLSPNWPEPYG---RGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
VL P P G D WG + + DG
Sbjct: 3096 ---------VLCPQPPPVQNGTVEGSDFRWGSSIS-------------------YSCMDG 3127
Query: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
L+ + G R +K + F DPG G G
Sbjct: 3128 YQLSHSAILSCEG-RGVWK--GEIPQCLPVFCGDPGIPAEGRLSG--------------- 3169
Query: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
+ + V +QC + +VGSS +CQ D TWS P+C
Sbjct: 3170 --------------KSFTYKSEVFFQCKSPFILVGSSRRVCQADGTWSGIQPTCIDPAHN 3215
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
+C DPG H SS + VG+TV + C +G+ + GS+ TC + WS +
Sbjct: 3216 TCPDPG-TPHFGIQNSSRGYEVGSTVFFRCRKGYHIQGSTTRTC----LANLTWSGIQTE 3270
Query: 830 CLLEQLKPCHGLSAPENGARSPEK--QLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
C+ H PE A + + L G T+ ++C PG+ L G + +
Sbjct: 3271 CIP------HACRQPETPAHADVRAIDLPTFGYTLVYTCHPGFFLAGGSEHRTCKA-DMK 3323
Query: 888 WSDPPPICRA 897
W+ P+C++
Sbjct: 3324 WTGKSPVCKS 3333
Score = 80.5 bits (197), Expect = 7e-15
Identities = 56/207 (27%), Positives = 88/207 (42%), Gaps = 17/207 (8%)
Query: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
CP+ P + NG S + G+ ++Y C GYQ+ S++L C+ W ++P C V
Sbjct: 3098 CPQPPPVQNGTVEGS--DFRWGSSISYSCMDGYQLSHSAILSCEGRGVWKGEIPQCLPV- 3154
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
C DPG R +S F + V + C F+L+GSS C WS P
Sbjct: 3155 FCGDPGIPAEGR--LSGKSFTYKSEVFFQCKSPFILVGSSRRVCQ----ADGTWSGIQPT 3208
Query: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 889
C+ C P G ++ + + G+T+ F C GY ++G + C+ WS
Sbjct: 3209 CIDPAHNTCPDPGTPHFGIQNSSRG-YEVGSTVFFRCRKGYHIQGSTTRTCLAN--LTWS 3265
Query: 890 D-----PPPICRAASLDGFYNSRSLDV 911
P CR + R++D+
Sbjct: 3266 GIQTECIPHACRQPETPAHADVRAIDL 3292
Score = 76.3 bits (186), Expect = 1e-13
Identities = 49/169 (28%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 734 VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGA 793
V YQC PG+++VG+SV +C D WS P C +T C PG+ H + +F +
Sbjct: 2703 VVYQCNPGFRLVGTSVRICLQDHKWSGQTPVCVPIT-CGHPGNPAHG--FTNGSEFNLND 2759
Query: 794 TVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEK 853
V + C+ G++L G S C + +WS P C ++ C EN R ++
Sbjct: 2760 VVNFTCNTGYLLQGVSRAQCR----SNGQWSSPLPTC---RVVNCSDPGFVENAIRHGQQ 2812
Query: 854 QLHPA---GATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
+ G +I + C G+ L G +++ C+ W P C A S
Sbjct: 2813 NFPESFEYGMSILYHCKKGFYLLGSSALTCMAN--GLWDRSLPKCLAIS 2859
Score = 71.6 bits (174), Expect = 3e-12
Identities = 59/195 (30%), Positives = 84/195 (43%), Gaps = 24/195 (12%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
+C L PNG K + V+G + C GY +VGS V C + WS C
Sbjct: 2622 SCGSLSFPPNGNKIGTLT--VYGATAIFTCNTGYTLVGSHVRECLANGLWSGSETRC-LA 2678
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
C P + + IS F TV Y C+ GF L+G+S+ C KWS + P
Sbjct: 2679 GHCGSPDPIVNGH--ISGDGFSYRDTVVYQCNPGFRLVGTSVRIC----LQDHKWSGQTP 2732
Query: 829 KCLL----EQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGH 884
C+ P HG + NG+ E L+ ++F+C GY+L+G + +C
Sbjct: 2733 VCVPITCGHPGNPAHGFT---NGS---EFNLND---VVNFTCNTGYLLQGVSRAQCRSN- 2782
Query: 885 PSHWSDPPPICRAAS 899
WS P P CR +
Sbjct: 2783 -GQWSSPLPTCRVVN 2796
Score = 47.4 bits (111), Expect = 7e-05
Identities = 49/158 (31%), Positives = 66/158 (41%), Gaps = 37/158 (23%)
Query: 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFV-LMGSSILTCHDRQAGSPKWSDRAPK 829
CHDPG + RR +F +G++V + CD GFV GS +TC Q G+ WS P+
Sbjct: 698 CHDPGIPINGRRF--GDRFLLGSSVSFHCDDGFVKTQGSESITC-ILQDGNVVWSSTVPR 754
Query: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYV---LKGQASIKCVPGHPS 886
C PC G +G + P G PGY L + I+ PGH
Sbjct: 755 C----EAPCGGHLTASSGV------ILPPG-------WPGYYKDSLHCEWIIEAKPGHSI 797
Query: 887 HWSDPPPICRAASLDGF---YNSRSLDVAKAPAASSTL 921
+ D F N +L+V PA+SS L
Sbjct: 798 ----------KITFDRFQTEVNYDTLEVRDGPASSSPL 825
Score = 47.0 bits (110), Expect = 9e-05
Identities = 20/46 (43%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 859 GATIHFSCAPGYVLKGQASIKCV--PGHPSHWSDPPPICRAASLDG 902
G I +SC PGY+L+G A + C+ PG+ + W P P CRA G
Sbjct: 164 GDKIRYSCLPGYILEGHAILTCIVSPGNGASWDFPAPFCRAEGACG 209
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sapiens]
Length = 3667
Score = 233 bits (594), Expect = 7e-61
Identities = 157/514 (30%), Positives = 240/514 (46%), Gaps = 16/514 (3%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
PC + +G++ SP P D L+C + I+V G G++++V + +
Sbjct: 1898 PCGGILTKRKGTILSP-GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1956
Query: 303 LGGPDPLP-LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
GG + P L + S ++ S ++ L FQS + G FH Y A L SC P
Sbjct: 1957 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIGLDSCPEP 2015
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
+ P+ G G F C GY L+G H+TC+ W+ P+C+A CGG +
Sbjct: 2016 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2075
Query: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
+ + G I+SPGFPGNY ++L C W + P G +HL F S D L +R+G + E
Sbjct: 2076 SDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSS-E 2133
Query: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
V +P L S+ + +D S G + Y+A+Q C +P
Sbjct: 2134 TSTVIGRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRN 2192
Query: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
F + VG T+ F C PGYTL G+ + C+ WN P C A+C G IT
Sbjct: 2193 GFVIGND-FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGNITAM 2250
Query: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGP-GDVLTFYDGDDLTARVL 659
G + SP +P+ Y QDC W V V I ++ VL+ P D +T +DG D + +
Sbjct: 2251 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2310
Query: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
GQ+SG + ++++ + I+F SD TS GF + + + C P +PN
Sbjct: 2311 GQFSGNTALESVYSTSNQILIKFHSDFTTS------GFFVLSYHAYQLRVCQPPPPVPNA 2364
Query: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQ 753
E G ++ YQC PG+ +VG+++L C+
Sbjct: 2365 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2398
Score = 224 bits (570), Expect = 4e-58
Identities = 180/614 (29%), Positives = 265/614 (43%), Gaps = 37/614 (6%)
Query: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
G GI T+T S +SG E T+ + P P C + + EG L S
Sbjct: 1155 GFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLS 1214
Query: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLANQSF 316
P + + +C + I V G G+ I + L +G+ + + +G L A
Sbjct: 1215 P-NYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGA 1273
Query: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
+RG + S ++Q L F S G F Y ++ LS C P P +G H
Sbjct: 1274 SMRGLTLSSTSNQLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHF 1332
Query: 376 GGSARFH-CATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFP 434
GS + C GY L G+ L C+ + WD P CIA CGG + ++GRI+SPG+P
Sbjct: 1333 AGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1392
Query: 435 GNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEY-- 492
Y NNL C W++E G + L F D L + +G PP D E
Sbjct: 1393 FPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG-----PPENDMLLKEISG 1447
Query: 493 -LPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
L EG+ S+ ++ TD + +G A+++ + C +P V + P
Sbjct: 1448 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREP- 1506
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAVCSGEITDSAGVVLSPNWP 610
G TV F CDPGY L QG I C+ + W + P C A C G +T S+G +LSPN+P
Sbjct: 1507 GDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1565
Query: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
PY +DC W + V D I L I P D L YDG D + ++G + +
Sbjct: 1566 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1625
Query: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
++ +S + + F+SD S G+ ++ ++C + I NG + +L
Sbjct: 1626 RIESSSNTMHLAFRSDGSVSYTGFHLE-----YKAKLRESCFDPGNIMNGTRLGMDYKL- 1679
Query: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
G+ VTY C GY + G S L C W+ LPSC G S +
Sbjct: 1680 -GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTG----SEGTVL 1734
Query: 786 SPKFPVGATVQYIC 799
SP +P +V + C
Sbjct: 1735 SPNYPKNYSVGHNC 1748
Score = 219 bits (559), Expect = 8e-57
Identities = 182/653 (27%), Positives = 289/653 (44%), Gaps = 51/653 (7%)
Query: 269 LDCFFYISVYPGYGVEIKVQNIS---------LREG--ETVTVEG-LGGPDPLPLANQSF 316
LDC + I++ G+GV ++ N S +R G ET TV G L GP +P +
Sbjct: 2095 LDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ-IPSS---- 2149
Query: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFPRRPAYGDVTVTSLHP 375
+ S TH+ +L F S G FH YQAY L SC PR G V
Sbjct: 2150 ------LFSTTHETSLYFHSDYSQNKQG-FHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV 2202
Query: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
G + F C GY L G LTCL+ W+ P C A CGG I A G I SPG+P
Sbjct: 2203 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNI-TAMNGTIYSPGYPD 2261
Query: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Y N C WL+ P G ++++F + D + + +G + +P + +
Sbjct: 2262 EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI--GQFSGNTAL 2319
Query: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPF-VKYGNFSSSTPTYPVGTT 554
E + S+ ++ +D + + L Y A+Q C P V + + +G
Sbjct: 2320 ESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDI 2378
Query: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC-SGEIT-DSAGVVLSPNWPEP 612
+ + C PG+TL G+ I+ C Q + P C+ +C + E+ DS GV+LSP +P+
Sbjct: 2379 IRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2437
Query: 613 YGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGP-RSHFK 670
Y Q C W + VE+ I + + + DVL YDG ++ + VL SG S F
Sbjct: 2438 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2497
Query: 671 LFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH 730
+ ++ +V +Q+ +D G + G++ ++ + P + P+G+ SQ
Sbjct: 2498 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESP--------PHGY-IISQTGGQL 2548
Query: 731 GTVVTYQCYPGYQVVGSSVLMCQWDL----TWSEDLPSCQRVTSCHDPGDVEHSRRLISS 786
+VV + C G+++VG S +C+ W +P+CQ + SC P + I +
Sbjct: 2549 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGG--ILT 2605
Query: 787 PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPEN 846
+ VG V Y C+ G+ L + T + G+ ++ P+C++ +
Sbjct: 2606 TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHG 2665
Query: 847 GARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
R + + FSC PGY G ASI+C+P W + P C+ S
Sbjct: 2666 RWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIIS 2718
Score = 206 bits (525), Expect = 7e-53
Identities = 191/713 (26%), Positives = 293/713 (41%), Gaps = 78/713 (10%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
PC +FS P G + SP D L+C + I PG+ ++I + V +E
Sbjct: 854 PCGGHFSAPSGVILSPGWPGYYKD-SLNCEWVIEAEPGHSIKITFERFQTELNYDV-LEV 911
Query: 303 LGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL---SC 357
GP+ L L + + Q + S ++ L F + + G F HY++ + SC
Sbjct: 912 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNG-FKIHYESVTVNTYSC 970
Query: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
P P +G G + F C +GY+L L C +W P C A CG
Sbjct: 971 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC--EKNHWWSHPLPTCDALCG 1028
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
G +R + G I+SPG+P Y N+L C W ++ G+ + +F L + D L+I
Sbjct: 1029 GDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1087
Query: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFV 537
+ P + I L + +D S + G + + + C +P +
Sbjct: 1088 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1147
Query: 538 -KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGE 596
+YG S + +G T+ FSC GY LE S II C+ W+ P C A C
Sbjct: 1148 PQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEII-CLGGGRRVWSAPLPRCVAECGAS 1204
Query: 597 ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTA 656
T++ G++LSPN+P Y +CI+ + V+ K I + R + GDVL YDG D T
Sbjct: 1205 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1264
Query: 657 RVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPE 715
+LG ++G +S ++ + ++F SD + G+Q V FE+ + P +P+
Sbjct: 1265 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ--LVYTSFELSHCED-PGIPQ 1321
Query: 716 IPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVTSCHD 773
G+K Q T++ Y C PGY + GSS+L C W LPSC + C
Sbjct: 1322 F--GYKISDQGHFAGSTII-YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAECGG 1376
Query: 774 PGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----MGSSILTCHD--RQAGSP 821
E S R++S P +P C D G ++ + HD R P
Sbjct: 1377 RFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1435
Query: 822 KWSDRAPKCLLEQLKP------------------------------------CHGLSAPE 845
+D K + L P C P
Sbjct: 1436 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1495
Query: 846 NGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH-WSDPPPICRA 897
NG R+ + + G T+ F C PGY L+G+ I C+ + W PP+C A
Sbjct: 1496 NGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1546
Score = 190 bits (482), Expect = 7e-48
Identities = 152/556 (27%), Positives = 234/556 (42%), Gaps = 28/556 (5%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYIS-VYPGYGVEIKVQNISLREGETVTVEG 302
C N GP G+ SP + D C + I+ V ++I + L G G
Sbjct: 508 CGSNLQGPSGTFTSP-NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 566
Query: 303 LGGP--DP---LPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSC 357
GG DP L + SF+ +I S + Q L Q+ G + + SC
Sbjct: 567 DGGEVGDPRTVLQVLTGSFV--PDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 624
Query: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
P P YG RF C G++L G + + C Q W + P+CI C
Sbjct: 625 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 682
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
A G ++SP +P Y NNL C W + + G R+HL F L D L +++GD
Sbjct: 683 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 741
Query: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFF-VELSTDSSGAAAGMALRYEAFQQGHCYEPF 536
+ E+ P+ ++ +P L+S H +E D S + G + Y F C +P
Sbjct: 742 SPES-PILGTFTGAEVPSH--LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 798
Query: 537 VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSG 595
+ N + +G+++ C+ G+ QG+ I C+ W+ P C A C G
Sbjct: 799 IPI-NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
Query: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL 654
+ +GV+LSP WP Y +C W + E I + + DVL +DG +L
Sbjct: 858 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 917
Query: 655 TARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELP 714
+ +LG Y+G + LF+S + + F +D S GF IH+ V N P
Sbjct: 918 LSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS----NNGFKIHYESVTVNTYSCLDP 973
Query: 715 EIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
IP + + G+ V++ C GY++ L+C+ + WS LP+C +
Sbjct: 974 GIPVHGRRYGH-DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG---- 1028
Query: 775 GDVEHSRRLISSPKFP 790
GDV I SP +P
Sbjct: 1029 GDVRGPSGTILSPGYP 1044
Score = 184 bits (467), Expect = 4e-46
Identities = 186/717 (25%), Positives = 300/717 (41%), Gaps = 86/717 (11%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
PC NF+ P G++ SP D L+C + I PG + + + L + + + V+
Sbjct: 680 PCLSNFTAPMGTVLSP-DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 738
Query: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFP 360
P+ L + + S +H L FQ+ +G G F+ Y + + C P
Sbjct: 739 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYNTFGHNECPDP 797
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACGG 418
P + G S C G+ + +G +TC L + W P C A CGG
Sbjct: 798 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
Query: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
+A +G I+SPG+PG Y ++L C W++EA G + + FE+ + D L + +G N
Sbjct: 858 HF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 916
Query: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--HCYEPF 536
+ +P + SY +P + L SS ++ +TD+S + G + YE+ C +P
Sbjct: 917 LLSP-LLGSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 974
Query: 537 V-----KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
+ +YG+ + +G+TV FSCD GY L ++ C H W+ P C A
Sbjct: 975 IPVHGRRYGH------DFSIGSTVSFSCDSGYRLSHEEPLL-CEKNH--WWSHPLPTCDA 1025
Query: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
+C G++ +G +LSP +PE Y +C W V V K + + + D L +
Sbjct: 1026 LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1085
Query: 651 GDDLT---ARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
T AR+ G P + L+ + ++F SD S +GF I F E
Sbjct: 1086 NGSFTQPLARLTGSDLPPTINAGLYGNFR-AQLRFISDFSISY----EGFNITFSEY-NL 1139
Query: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
+ C + P IP + S G +T+ C GY++ G+S ++C WS LP C
Sbjct: 1140 EPCED-PGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1197
Query: 766 QR------------VTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTC 813
+ S + P + E++ I S + G + I + F L +L
Sbjct: 1198 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGIN-ISARTFHLAQGDVLKI 1256
Query: 814 HDRQAGSPKW--------------SDRAPKCLLE-------------------QLKPCHG 840
+D + + S + + LE +L C
Sbjct: 1257 YDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED 1316
Query: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
P+ G + + Q H AG+TI + C PGY L G + +KC+ G W P P C A
Sbjct: 1317 PGIPQFGYKISD-QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1372
Score = 183 bits (465), Expect = 6e-46
Identities = 197/723 (27%), Positives = 292/723 (40%), Gaps = 96/723 (13%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-- 300
PC N +G G + SP + P DC + I+V Y + + + S+
Sbjct: 1547 PCGGNLTGSSGFILSP-NFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1605
Query: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHF 359
+G PL + Q L + I S ++ L F+S + G FH Y+A L SC
Sbjct: 1606 DGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTG-FHLEYKAKLRESCFD 1663
Query: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACG 417
P G G + ++C GY L+G LTC+ +P W+ P C A CG
Sbjct: 1664 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1723
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLI 472
+ G ++SP +P NYS C + + P+ GQ + F + SL D +
Sbjct: 1724 SR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV---FFQTSL---HDVVE 1776
Query: 473 IRNGDNVEAP---PVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
+ +G ++ + S+ E LP LSSG + ++ A G Y+A +
Sbjct: 1777 VYDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1832
Query: 530 GHCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWN 583
+ P ++G + + VG++V F C+PGY L GSI I C V QWN
Sbjct: 1833 TSSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWN 1889
Query: 584 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 643
++ P C C G +T G +LSP +PEPY +C+W + V E I + +
Sbjct: 1890 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1949
Query: 644 -DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
D L FYDG D A LG YSG L ++ ++ + FQSD S G+ +
Sbjct: 1950 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 2009
Query: 703 EVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSE 760
D+CPE P+ P+ +V G VV++QC GY + G S + C W+
Sbjct: 2010 -----DSCPE-PQTPSSGIKIGDRYMV-GDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 2062
Query: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQ------GF----VLMGSSI 810
+P C + C G + +I SP FP C GF + S
Sbjct: 2063 PIPIC--LAQC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2118
Query: 811 LTCHDR---QAGSPKWSD-----RAPKCLLEQLKPCHGLSAPENGARSPEKQ-LH----- 856
T HD ++GS + S P+ H S + S KQ H
Sbjct: 2119 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2178
Query: 857 ----------------------PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPI 894
G TI F C PGY L G +++ C+ G +W+ P P
Sbjct: 2179 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2238
Query: 895 CRA 897
C A
Sbjct: 2239 CEA 2241
Score = 153 bits (387), Expect = 7e-37
Identities = 146/604 (24%), Positives = 242/604 (40%), Gaps = 87/604 (14%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGL 303
C + GP G++ SP + L+C + + V G GV+ L + +
Sbjct: 1027 CGGDVRGPSGTILSPGYPEFYPN-SLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1085
Query: 304 GGPDPLPLANQSFLLRGQVIRSPTH---QAALRFQSLPPPAGPGTFHFHYQAYLLS-CHF 359
G PLA + I + + +A LRF S + G F+ + Y L C
Sbjct: 1086 NGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG-FNITFSEYNLEPCED 1144
Query: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGV 419
P P YG + G + F C++GY+L+G + CL + W + P C+A CG
Sbjct: 1145 PGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGAS 1204
Query: 420 IRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNV 479
N G ++SP +P NY NN C + ++ G+ +++ LA+ D I D
Sbjct: 1205 ATN-NEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD-- 1261
Query: 480 EAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKY 539
+ + ++ + L S+ ++E ++D+ G G L Y +F+ HC +P +
Sbjct: 1262 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQ 1321
Query: 540 GNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEIT- 598
+ S + G+T+ + C+PGYTL GS +++C+ W+ P+C A C G
Sbjct: 1322 FGYKISDQGHFAGSTIIYGCNPGYTLH-GSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1380
Query: 599 DSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARV 658
+S+G +LSP +P PY C+W + V+ PG++++
Sbjct: 1381 ESSGRILSPGYPFPYDNNLRCMWMIEVD---------------PGNIVSLQ--------- 1416
Query: 659 LGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPN 718
+ F ++ +L G P ND L EI
Sbjct: 1417 --------------------FLAFDTEASHDILRVWDG-------PPENDML--LKEISG 1447
Query: 719 GWKSPSQPELVHGT--VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGD 776
PE +H T +VT Q + + S + + +S + T+C DPG
Sbjct: 1448 SLI----PEGIHSTLNIVTIQFDTDFYISKSG-----FAIQFSSSV-----ATACRDPGV 1493
Query: 777 VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLK 836
+ R + G TV + CD G+ L G +TC + W P C +
Sbjct: 1494 PMNGTR--NGDGREPGDTVVFQCDPGYELQGEERITCIQVE-NRYFWQPSPPVC----IA 1546
Query: 837 PCHG 840
PC G
Sbjct: 1547 PCGG 1550
Score = 137 bits (344), Expect = 7e-32
Identities = 179/771 (23%), Positives = 289/771 (37%), Gaps = 136/771 (17%)
Query: 211 TITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSPTDVGLD 270
T+T +T++G+ EE TTT +T P DV +
Sbjct: 307 TLTHTTSTGELEEHNRTTTGAIAVAST--------------------------PADVTVS 340
Query: 271 CFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRG----QVIRSP 326
++++ E +VQ SLR G P P QS R Q+ R+
Sbjct: 341 SVTAVTIHR-LSEEQRVQVTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTK 399
Query: 327 -----THQA--ALRFQSLPPPAGPGTFHFHYQAYLLS---------CHFPRRPAYGDVTV 370
TH+ A+ F+S PG + + + L C P P G
Sbjct: 400 ELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIG 459
Query: 371 TSLHPGGSARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVC-IAACGGVIRNATTGR 427
+ G + +F C Y L+GA+ +TC + F W PVC + CG ++ + G
Sbjct: 460 SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GT 518
Query: 428 IVSPGFPGNYSNNLTCHWLLEAPEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAP-PVY 485
SP FP Y +N C W++ A + + ++FE+ L D L I +G V P V
Sbjct: 519 FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVL 578
Query: 486 DSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSS 545
++P + ++S ++ L TD S + G + Y+ ++ C +P
Sbjct: 579 QVLTGSFVP-DLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDP---------G 628
Query: 546 TPTYPV--------GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEI 597
TP Y + + F C G+ L G I C + + QW+ P C C
Sbjct: 629 TPLYGIREGDGFSNRDVLRFECQFGFEL-IGEKSIVCQE--NNQWSANIPICIFPCLSNF 685
Query: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTA 656
T G VLSP++PE YG +CIW + + RI L + D L DGD +
Sbjct: 686 TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPES 745
Query: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
+LG ++G L ++ + ++FQ+D S +GF I + N+ CP+ P I
Sbjct: 746 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMS----GRGFNITYNTFGHNE-CPD-PGI 799
Query: 717 P-NGWKSPSQPELVHGTVVTYQCYPGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSC 771
P N + +L G+ ++ C G+ + G+ + C + WS +P C
Sbjct: 800 PINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 857
Query: 772 HD------------PGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQ-- 817
H PG + S + G +++ ++ + +L HD
Sbjct: 858 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 917
Query: 818 ----AGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIH---------- 863
GS + P+ L + L +N + ++H T++
Sbjct: 918 LSPLLGSYN-GTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 976
Query: 864 -----------------FSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
FSC GY L + + C H WS P P C A
Sbjct: 977 VHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNH--WWSHPLPTCDA 1025
Score = 102 bits (254), Expect = 2e-21
Identities = 95/361 (26%), Positives = 151/361 (41%), Gaps = 19/361 (5%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
C N + G++ SP + DCF+ + V PG G+ I N ++ + E + +
Sbjct: 2243 CGGNITAMNGTIYSPGYPDEYPNFQ-DCFWLVRVPPGNGIYI---NFTVLQTEPIYDFIT 2298
Query: 302 GLGGPDP-LPLANQ-SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHF 359
GPD P Q S + + S ++Q ++F S G F Y AY L
Sbjct: 2299 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS--DFTTSGFFVLSYHAYQLRVCQ 2356
Query: 360 PRRPAYGDVTVTS---LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
P P +T G R+ C G+ L G LTC + D PVC C
Sbjct: 2357 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2416
Query: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
+R +TG I+SPG+P +Y N C W + +G + + E ++ D L + +
Sbjct: 2417 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2476
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
G N+++ PV S +Y + S+G F++ S D G +RY AF +C P
Sbjct: 2477 GPNIQS-PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTP 2532
Query: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL-EQGSIIIECVDPHDPQWNETEPACRAVCS 594
+ S + + V ++CD G+ L + S + W+ PAC+A+
Sbjct: 2533 ESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC 2592
Query: 595 G 595
G
Sbjct: 2593 G 2593
Score = 99.0 bits (245), Expect = 2e-20
Identities = 66/225 (29%), Positives = 103/225 (45%), Gaps = 9/225 (4%)
Query: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
I CGG ++ G I SPGFP Y N C W++ A E R+ + F+ +L E+ D L
Sbjct: 22 IYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 80
Query: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
+ +G P + + + + S+ F + L++D + +A G + YE Q C
Sbjct: 81 LYDGH--PHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 138
Query: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV--DPHDPQWNETEPACR 590
P V T + VG + +SC GY L+ G + C+ + W+ P CR
Sbjct: 139 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILD-GHPQLTCIANSVNTASWDFPVPICR 196
Query: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML 633
A C G + S+G++ SP++P Y DC W + E I L
Sbjct: 197 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 241
Score = 95.9 bits (237), Expect = 2e-19
Identities = 130/552 (23%), Positives = 194/552 (35%), Gaps = 144/552 (26%)
Query: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAA 415
+C P P +G ++ + R+ C TGY L G+ TCL W ++P C
Sbjct: 3015 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCL--ANGSWTGRQPEC--- 3069
Query: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
+ V G PG +N ++ +
Sbjct: 3070 -----------KAVQCGNPGTTANG-----------------------------KVFRID 3089
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
G + +Y +EG + SG ++G +G G P
Sbjct: 3090 GTTFSSSVIYSC-------MEGYILSGPSV---RQCTANGTWSGTLPNCTIISCGDPGIP 3139
Query: 536 F--VKYGNFSSSTPTYPVGTTVEFSCDPGYTLE-QGSIIIECVDPHDPQWNETEPACRAV 592
++YG+ Y VG V + C PGYT+E GS I C + W+ P CRAV
Sbjct: 3140 ANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSRIRTCT--INGTWSGVMPTCRAV 3191
Query: 593 -CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
C S G + N+ WG + PG L+F
Sbjct: 3192 TCPTPPQISNGRLEGTNFD----------WGFSIS-----------YICSPGYELSF--P 3228
Query: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
LT G +SG + +F DPG G ++G
Sbjct: 3229 AVLTCVGNGTWSG---------EVPQCLPKFCGDPGIPAQGKREG--------------- 3264
Query: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
++ + V++ C + +VGSS +CQ D TWS P C T
Sbjct: 3265 --------------KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3310
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
SC +PG H + ++ F VG+ VQ+ C +G +L GS+ TC WS P+
Sbjct: 3311 SCENPGVPRHGSQ-NNTFGFQVGSVVQFHCKKGHLLQGSTTRTC----LPDLTWSGIQPE 3365
Query: 830 CLLEQLKPCHGLSAPENGARS--PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
C+ H PE A + L G T+ ++C PG+ L G + V +
Sbjct: 3366 CI------PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNT 3418
Query: 888 WSDPPPICRAAS 899
W+ PIC A S
Sbjct: 3419 WTGKVPICEAGS 3430
Score = 95.1 bits (235), Expect = 3e-19
Identities = 138/570 (24%), Positives = 204/570 (35%), Gaps = 115/570 (20%)
Query: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDS--KEPVC 412
+SC P+ P G + T G + C GY+L T + + W + K P C
Sbjct: 2590 ISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRC 2649
Query: 413 IAA-CGGV---IRNATTGRIVS---------------PGFPGNYSNNLTC------HWLL 447
+ C + I RIV+ PG+ G ++ C W
Sbjct: 2650 VVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRN 2709
Query: 448 EAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFV 507
E P + + +S E NG+ + Y S + + G + G
Sbjct: 2710 ERP-------YCQIISCGELPTP---PNGNKIGTQTSYGSTAIFTCDL-GFMLVGSAVRE 2758
Query: 508 ELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQ 567
LS SG + R A GHC P + N Y TV + C+PG+ L
Sbjct: 2759 CLS---SGLWSESETRCLA---GHCGIPELIV-NGQVIGENYGYRDTVVYQCNPGFRLIG 2811
Query: 568 GSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEE 627
S+ I C H+ W+ P+C V S G SP + G G + +
Sbjct: 2812 SSVRI-CQQDHN--WSGQLPSCVPV-------SCGHPGSPIYGRTSGNG------FNFND 2855
Query: 628 DKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPG 687
+I L GP + Q+S P K+ SDPG
Sbjct: 2856 VVTFSCNIGYLMQGPTKA---------QCQANRQWSHPPPMCKVVNC---------SDPG 2897
Query: 688 TSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGS 747
+P N E N +GTVV Y C PGY + GS
Sbjct: 2898 ----------------IPANSKRESKIEHGN---------FTYGTVVFYDCNPGYFLFGS 2932
Query: 748 SVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMG 807
SVL+CQ + W + LP C + C PG ++ ++S K+ G+TV Y C L+G
Sbjct: 2933 SVLICQPNGQWDKPLPECIMI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLG 2989
Query: 808 SSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCA 867
S TC + WS P C + C P +G+R ++ +T+ ++C
Sbjct: 2990 QSSRTCQ----LNGHWSGSQPHCSGDATGTCGDPGTPGHGSR--QESNFRTKSTVRYACD 3043
Query: 868 PGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
GY+L G C+ W+ P C+A
Sbjct: 3044 TGYILHGSEERTCLAN--GSWTGRQPECKA 3071
Score = 86.7 bits (213), Expect = 1e-16
Identities = 153/607 (25%), Positives = 217/607 (35%), Gaps = 141/607 (23%)
Query: 354 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
++SC P G+ T G +A F C G+ L G+ CL++ W E C+
Sbjct: 2716 IISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2773
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
A G+ G+++ + Y + + + + G R L V + + D
Sbjct: 2774 AGHCGIPELIVNGQVIGENY--GYRDTV----VYQCNPGFR--LIGSSVRICQQDHNW-- 2823
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--- 530
+G PV + PI G S F ++ T S M +A Q
Sbjct: 2824 -SGQLPSCVPVSCGHPGS--PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2880
Query: 531 -----------HCYEP----------FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGS 569
+C +P +++GNF TY GT V + C+PGY L S
Sbjct: 2881 WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNF-----TY--GTVVFYDCNPGYFLFGSS 2933
Query: 570 IIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVE-ED 628
++I P+ QW++ P C + G VLS E Y G VH
Sbjct: 2934 VLI--CQPNG-QWDKPLPECIMIDCGHPGVPPNAVLS---GEKYTFGST----VHYSCTG 2983
Query: 629 KRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGT 688
KR +L T ++ G +SG + H D T DPGT
Sbjct: 2984 KRSLL----------------GQSSRTCQLNGHWSGSQPH-----CSGDAT-GTCGDPGT 3021
Query: 689 SVLGYQQ----------------GFVIHFFEVPRNDTCPELPEIPNGWKSPSQPEL---- 728
G +Q G+++H E TC + NG + QPE
Sbjct: 3022 PGHGSRQESNFRTKSTVRYACDTGYILHGSE---ERTC-----LANGSWTGRQPECKAVQ 3073
Query: 729 --------------VHGTV----VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTS 770
+ GT V Y C GY + G SV C + TWS LP+C + S
Sbjct: 3074 CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIIS 3132
Query: 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFV--LMGSSILTCHDRQAGSPKWSDRAP 828
C DPG + R + VG V Y+C G+ L GS I TC + WS P
Sbjct: 3133 CGDPGIPANGLRY--GDDYVVGQNVSYMCQPGYTMELNGSRIRTC----TINGTWSGVMP 3186
Query: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
C + C NG E G +I + C+PGY L A + CV W
Sbjct: 3187 TC---RAVTCPTPPQISNGRL--EGTNFDWGFSISYICSPGYELSFPAVLTCVGN--GTW 3239
Query: 889 SDPPPIC 895
S P C
Sbjct: 3240 SGEVPQC 3246
Score = 79.3 bits (194), Expect = 2e-14
Identities = 79/291 (27%), Positives = 114/291 (39%), Gaps = 21/291 (7%)
Query: 244 CSWNFSGPEGSLDSPT-DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
C G G+++SP P G +C + I ++I Q+ +L E
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPN--GANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 82
Query: 303 LGGPDPLPLANQSFLLRGQVIRSPTHQA----ALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
G P P N L G + P +LR S + G ++ + SC
Sbjct: 83 DGHPHP---TNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 139
Query: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL--NATQPFWDSKEPVCIA-- 414
P P G + T G R+ C TGY L G LTC+ + WD P+C A
Sbjct: 140 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 199
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
ACGG +R ++ G I SP FP Y NN C W + A G + L F + E D L I
Sbjct: 200 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 258
Query: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYE 525
+ PP + P ++S+ + TDS+ G + Y+
Sbjct: 259 GSE----PPTIWLSGMNIPP--PIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 74.7 bits (182), Expect = 4e-13
Identities = 55/191 (28%), Positives = 82/191 (42%), Gaps = 16/191 (8%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
+C ELP PNG K +Q +G+ + C G+ +VGS+V C WSE C
Sbjct: 2718 SCGELPTPPNGNKIGTQTS--YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL-A 2774
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
C P + + + + + TV Y C+ GF L+GSS+ C WS + P
Sbjct: 2775 GHCGIPELIVNGQ--VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH----NWSGQLP 2828
Query: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
C+ C +P G S + FSC GY+++G +C W
Sbjct: 2829 SCVPVS---CGHPGSPIYGRTSGNG--FNFNDVVTFSCNIGYLMQGPTKAQCQANR--QW 2881
Query: 889 SDPPPICRAAS 899
S PPP+C+ +
Sbjct: 2882 SHPPPMCKVVN 2892
Score = 58.5 bits (140), Expect = 3e-08
Identities = 48/203 (23%), Positives = 86/203 (42%), Gaps = 14/203 (6%)
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDG 651
C G + G + SP +P Y G +C W + EE RI + + + D L+ YDG
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 84
Query: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
+ +G + ++ + +++ SD S G++ ++E ++ +C
Sbjct: 85 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-----YYEELQSSSCG 139
Query: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD----LTWSEDLPSCQR 767
P G ++ ++ G + Y C GY + G L C + +W +P C+
Sbjct: 140 NPGVPPKGVLYGTRFDV--GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 197
Query: 768 VTSCHDPGDVEHSRRLISSPKFP 790
+C G + S +ISSP FP
Sbjct: 198 EDAC--GGTMRGSSGIISSPSFP 218
Score = 39.3 bits (90), Expect = 0.019
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 859 GATIHFSCAPGYVLKGQASIKCVPG--HPSHWSDPPPICRAASLDGFYNSRSLDVAKAPA 916
G I +SC GY+L G + C+ + + W P PICRA G S + +P+
Sbjct: 157 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPS 216
Score = 37.7 bits (86), Expect = 0.054
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
+SC +PG + ++ +F VG ++Y C G++L G LTC + W P
Sbjct: 136 SSCGNPG--VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 193
Query: 829 KCLLEQLKPCHGLSAPENGARS----PEKQLHPAGATIHFSCAPG 869
C E C G +G S P + + A T PG
Sbjct: 194 ICRAED--ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPG 236
Score = 33.5 bits (75), Expect = 1.0
Identities = 50/237 (21%), Positives = 85/237 (35%), Gaps = 63/237 (26%)
Query: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPVCI 413
++C P + + G + T+ G S + C+ GY+L LTC+ N T W + P C+
Sbjct: 3191 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3247
Query: 414 AA-CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
CG PG P EG+ ++ +VS + + ++
Sbjct: 3248 PKFCG------------DPGIPAQGKR-----------EGKSF-IYQSEVSFSCNFPFIL 3283
Query: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
+ + + +G S +E + S C
Sbjct: 3284 VGSSTRI-------------CQADGTWSGSSPHCIEPTQTS------------------C 3312
Query: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
P V ++T + VG+ V+F C G+ L QGS C+ D W+ +P C
Sbjct: 3313 ENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLL-QGSTTRTCLP--DLTWSGIQPEC 3366
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 233 bits (594), Expect = 7e-61
Identities = 157/514 (30%), Positives = 240/514 (46%), Gaps = 16/514 (3%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
PC + +G++ SP P D L+C + I+V G G++++V + +
Sbjct: 1834 PCGGILTKRKGTILSP-GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1892
Query: 303 LGGPDPLP-LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
GG + P L + S ++ S ++ L FQS + G FH Y A L SC P
Sbjct: 1893 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIGLDSCPEP 1951
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
+ P+ G G F C GY L+G H+TC+ W+ P+C+A CGG +
Sbjct: 1952 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2011
Query: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
+ + G I+SPGFPGNY ++L C W + P G +HL F S D L +R+G + E
Sbjct: 2012 SDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSS-E 2069
Query: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
V +P L S+ + +D S G + Y+A+Q C +P
Sbjct: 2070 TSTVIGRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRN 2128
Query: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
F + VG T+ F C PGYTL G+ + C+ WN P C A+C G IT
Sbjct: 2129 GFVIGND-FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGNITAM 2186
Query: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGP-GDVLTFYDGDDLTARVL 659
G + SP +P+ Y QDC W V V I ++ VL+ P D +T +DG D + +
Sbjct: 2187 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2246
Query: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
GQ+SG + ++++ + I+F SD TS GF + + + C P +PN
Sbjct: 2247 GQFSGNTALESVYSTSNQILIKFHSDFTTS------GFFVLSYHAYQLRVCQPPPPVPNA 2300
Query: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQ 753
E G ++ YQC PG+ +VG+++L C+
Sbjct: 2301 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2334
Score = 224 bits (570), Expect = 4e-58
Identities = 180/614 (29%), Positives = 265/614 (43%), Gaps = 37/614 (6%)
Query: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
G GI T+T S +SG E T+ + P P C + + EG L S
Sbjct: 1091 GFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLS 1150
Query: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLANQSF 316
P + + +C + I V G G+ I + L +G+ + + +G L A
Sbjct: 1151 P-NYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGA 1209
Query: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
+RG + S ++Q L F S G F Y ++ LS C P P +G H
Sbjct: 1210 SMRGLTLSSTSNQLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHF 1268
Query: 376 GGSARFH-CATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFP 434
GS + C GY L G+ L C+ + WD P CIA CGG + ++GRI+SPG+P
Sbjct: 1269 AGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1328
Query: 435 GNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEY-- 492
Y NNL C W++E G + L F D L + +G PP D E
Sbjct: 1329 FPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG-----PPENDMLLKEISG 1383
Query: 493 -LPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
L EG+ S+ ++ TD + +G A+++ + C +P V + P
Sbjct: 1384 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREP- 1442
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAVCSGEITDSAGVVLSPNWP 610
G TV F CDPGY L QG I C+ + W + P C A C G +T S+G +LSPN+P
Sbjct: 1443 GDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1501
Query: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
PY +DC W + V D I L I P D L YDG D + ++G + +
Sbjct: 1502 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1561
Query: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
++ +S + + F+SD S G+ ++ ++C + I NG + +L
Sbjct: 1562 RIESSSNTMHLAFRSDGSVSYTGFHLE-----YKAKLRESCFDPGNIMNGTRLGMDYKL- 1615
Query: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
G+ VTY C GY + G S L C W+ LPSC G S +
Sbjct: 1616 -GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTG----SEGTVL 1670
Query: 786 SPKFPVGATVQYIC 799
SP +P +V + C
Sbjct: 1671 SPNYPKNYSVGHNC 1684
Score = 213 bits (543), Expect = 5e-55
Identities = 183/651 (28%), Positives = 293/651 (45%), Gaps = 58/651 (8%)
Query: 269 LDCFFYISVYPGYGVEIKVQNIS---------LREG--ETVTVEG-LGGPDPLPLANQSF 316
LDC + I++ G+GV ++ N S +R G ET TV G L GP +P +
Sbjct: 2031 LDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ-IPSS---- 2085
Query: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFPRRPAYGDVTVTSLHP 375
+ S TH+ +L F S G FH YQAY L SC PR G V
Sbjct: 2086 ------LFSTTHETSLYFHSDYSQNKQG-FHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV 2138
Query: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
G + F C GY L G LTCL+ W+ P C A CGG I A G I SPG+P
Sbjct: 2139 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNI-TAMNGTIYSPGYPD 2197
Query: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Y N C WL+ P G ++++F + D + + +G + +P + +
Sbjct: 2198 EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI--GQFSGNTAL 2255
Query: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPF-VKYGNFSSSTPTYPVGTT 554
E + S+ ++ +D + + L Y A+Q C P V + + +G
Sbjct: 2256 ESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDI 2314
Query: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC-SGEIT-DSAGVVLSPNWPEP 612
+ + C PG+TL G+ I+ C Q + P C+ +C + E+ DS GV+LSP +P+
Sbjct: 2315 IRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2373
Query: 613 YGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGP-RSHFK 670
Y Q C W + VE+ I + + + DVL YDG ++ + VL SG S F
Sbjct: 2374 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2433
Query: 671 LFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH 730
+ ++ +V +Q+ +D G + G++ ++ + P + P+G+ SQ
Sbjct: 2434 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESP--------PHGY-IISQTGGQL 2484
Query: 731 GTVVTYQCYPGYQVVGSSVLMCQWDL----TWSEDLPSCQRVTSCHDPGDVEHSRRLISS 786
+VV + C G+++VG S +C+ W +P+CQ + SC P + I +
Sbjct: 2485 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGG--ILT 2541
Query: 787 PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPEN 846
+ VG V Y C+ G+ L + T + G+ ++ P+C++ C L P N
Sbjct: 2542 TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVIS---CGELPTPPN 2598
Query: 847 GARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
G + + + G+T F+C G++L G A +C+ WS+ C A
Sbjct: 2599 GNKIGTQTSY--GSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCLA 2645
Score = 206 bits (525), Expect = 7e-53
Identities = 191/713 (26%), Positives = 293/713 (41%), Gaps = 78/713 (10%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
PC +FS P G + SP D L+C + I PG+ ++I + V +E
Sbjct: 790 PCGGHFSAPSGVILSPGWPGYYKD-SLNCEWVIEAEPGHSIKITFERFQTELNYDV-LEV 847
Query: 303 LGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL---SC 357
GP+ L L + + Q + S ++ L F + + G F HY++ + SC
Sbjct: 848 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNG-FKIHYESVTVNTYSC 906
Query: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
P P +G G + F C +GY+L L C +W P C A CG
Sbjct: 907 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC--EKNHWWSHPLPTCDALCG 964
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
G +R + G I+SPG+P Y N+L C W ++ G+ + +F L + D L+I
Sbjct: 965 GDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1023
Query: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFV 537
+ P + I L + +D S + G + + + C +P +
Sbjct: 1024 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1083
Query: 538 -KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGE 596
+YG S + +G T+ FSC GY LE S II C+ W+ P C A C
Sbjct: 1084 PQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEII-CLGGGRRVWSAPLPRCVAECGAS 1140
Query: 597 ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTA 656
T++ G++LSPN+P Y +CI+ + V+ K I + R + GDVL YDG D T
Sbjct: 1141 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1200
Query: 657 RVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPE 715
+LG ++G +S ++ + ++F SD + G+Q V FE+ + P +P+
Sbjct: 1201 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ--LVYTSFELSHCED-PGIPQ 1257
Query: 716 IPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVTSCHD 773
G+K Q T++ Y C PGY + GSS+L C W LPSC + C
Sbjct: 1258 F--GYKISDQGHFAGSTII-YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAECGG 1312
Query: 774 PGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----MGSSILTCHD--RQAGSP 821
E S R++S P +P C D G ++ + HD R P
Sbjct: 1313 RFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1371
Query: 822 KWSDRAPKCLLEQLKP------------------------------------CHGLSAPE 845
+D K + L P C P
Sbjct: 1372 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1431
Query: 846 NGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH-WSDPPPICRA 897
NG R+ + + G T+ F C PGY L+G+ I C+ + W PP+C A
Sbjct: 1432 NGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1482
Score = 190 bits (482), Expect = 7e-48
Identities = 152/556 (27%), Positives = 234/556 (42%), Gaps = 28/556 (5%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYIS-VYPGYGVEIKVQNISLREGETVTVEG 302
C N GP G+ SP + D C + I+ V ++I + L G G
Sbjct: 444 CGSNLQGPSGTFTSP-NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 502
Query: 303 LGGP--DP---LPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSC 357
GG DP L + SF+ +I S + Q L Q+ G + + SC
Sbjct: 503 DGGEVGDPRTVLQVLTGSFV--PDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 560
Query: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
P P YG RF C G++L G + + C Q W + P+CI C
Sbjct: 561 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 618
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
A G ++SP +P Y NNL C W + + G R+HL F L D L +++GD
Sbjct: 619 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 677
Query: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFF-VELSTDSSGAAAGMALRYEAFQQGHCYEPF 536
+ E+ P+ ++ +P L+S H +E D S + G + Y F C +P
Sbjct: 678 SPES-PILGTFTGAEVPSH--LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 734
Query: 537 VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSG 595
+ N + +G+++ C+ G+ QG+ I C+ W+ P C A C G
Sbjct: 735 IPI-NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 793
Query: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL 654
+ +GV+LSP WP Y +C W + E I + + DVL +DG +L
Sbjct: 794 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 853
Query: 655 TARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELP 714
+ +LG Y+G + LF+S + + F +D S GF IH+ V N P
Sbjct: 854 LSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS----NNGFKIHYESVTVNTYSCLDP 909
Query: 715 EIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
IP + + G+ V++ C GY++ L+C+ + WS LP+C +
Sbjct: 910 GIPVHGRRYGH-DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG---- 964
Query: 775 GDVEHSRRLISSPKFP 790
GDV I SP +P
Sbjct: 965 GDVRGPSGTILSPGYP 980
Score = 184 bits (467), Expect = 4e-46
Identities = 186/717 (25%), Positives = 300/717 (41%), Gaps = 86/717 (11%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
PC NF+ P G++ SP D L+C + I PG + + + L + + + V+
Sbjct: 616 PCLSNFTAPMGTVLSP-DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 674
Query: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFP 360
P+ L + + S +H L FQ+ +G G F+ Y + + C P
Sbjct: 675 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYNTFGHNECPDP 733
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACGG 418
P + G S C G+ + +G +TC L + W P C A CGG
Sbjct: 734 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 793
Query: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
+A +G I+SPG+PG Y ++L C W++EA G + + FE+ + D L + +G N
Sbjct: 794 HF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 852
Query: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--HCYEPF 536
+ +P + SY +P + L SS ++ +TD+S + G + YE+ C +P
Sbjct: 853 LLSP-LLGSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 910
Query: 537 V-----KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
+ +YG+ + +G+TV FSCD GY L ++ C H W+ P C A
Sbjct: 911 IPVHGRRYGH------DFSIGSTVSFSCDSGYRLSHEEPLL-CEKNH--WWSHPLPTCDA 961
Query: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
+C G++ +G +LSP +PE Y +C W V V K + + + D L +
Sbjct: 962 LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1021
Query: 651 GDDLT---ARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
T AR+ G P + L+ + ++F SD S +GF I F E
Sbjct: 1022 NGSFTQPLARLTGSDLPPTINAGLYGNFR-AQLRFISDFSISY----EGFNITFSEY-NL 1075
Query: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
+ C + P IP + S G +T+ C GY++ G+S ++C WS LP C
Sbjct: 1076 EPCED-PGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1133
Query: 766 QR------------VTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTC 813
+ S + P + E++ I S + G + I + F L +L
Sbjct: 1134 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGIN-ISARTFHLAQGDVLKI 1192
Query: 814 HDRQAGSPKW--------------SDRAPKCLLE-------------------QLKPCHG 840
+D + + S + + LE +L C
Sbjct: 1193 YDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED 1252
Query: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
P+ G + + Q H AG+TI + C PGY L G + +KC+ G W P P C A
Sbjct: 1253 PGIPQFGYKISD-QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1308
Score = 183 bits (465), Expect = 6e-46
Identities = 197/723 (27%), Positives = 292/723 (40%), Gaps = 96/723 (13%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-- 300
PC N +G G + SP + P DC + I+V Y + + + S+
Sbjct: 1483 PCGGNLTGSSGFILSP-NFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1541
Query: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHF 359
+G PL + Q L + I S ++ L F+S + G FH Y+A L SC
Sbjct: 1542 DGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTG-FHLEYKAKLRESCFD 1599
Query: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACG 417
P G G + ++C GY L+G LTC+ +P W+ P C A CG
Sbjct: 1600 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1659
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLI 472
+ G ++SP +P NYS C + + P+ GQ + F + SL D +
Sbjct: 1660 SR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV---FFQTSL---HDVVE 1712
Query: 473 IRNGDNVEAP---PVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
+ +G ++ + S+ E LP LSSG + ++ A G Y+A +
Sbjct: 1713 VYDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1768
Query: 530 GHCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWN 583
+ P ++G + + VG++V F C+PGY L GSI I C V QWN
Sbjct: 1769 TSSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWN 1825
Query: 584 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 643
++ P C C G +T G +LSP +PEPY +C+W + V E I + +
Sbjct: 1826 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1885
Query: 644 -DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
D L FYDG D A LG YSG L ++ ++ + FQSD S G+ +
Sbjct: 1886 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 1945
Query: 703 EVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSE 760
D+CPE P+ P+ +V G VV++QC GY + G S + C W+
Sbjct: 1946 -----DSCPE-PQTPSSGIKIGDRYMV-GDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 1998
Query: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQ------GF----VLMGSSI 810
+P C + C G + +I SP FP C GF + S
Sbjct: 1999 PIPIC--LAQC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2054
Query: 811 LTCHDR---QAGSPKWSD-----RAPKCLLEQLKPCHGLSAPENGARSPEKQ-LH----- 856
T HD ++GS + S P+ H S + S KQ H
Sbjct: 2055 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2114
Query: 857 ----------------------PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPI 894
G TI F C PGY L G +++ C+ G +W+ P P
Sbjct: 2115 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2174
Query: 895 CRA 897
C A
Sbjct: 2175 CEA 2177
Score = 153 bits (387), Expect = 7e-37
Identities = 146/604 (24%), Positives = 242/604 (40%), Gaps = 87/604 (14%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGL 303
C + GP G++ SP + L+C + + V G GV+ L + +
Sbjct: 963 CGGDVRGPSGTILSPGYPEFYPN-SLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1021
Query: 304 GGPDPLPLANQSFLLRGQVIRSPTH---QAALRFQSLPPPAGPGTFHFHYQAYLLS-CHF 359
G PLA + I + + +A LRF S + G F+ + Y L C
Sbjct: 1022 NGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG-FNITFSEYNLEPCED 1080
Query: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGV 419
P P YG + G + F C++GY+L+G + CL + W + P C+A CG
Sbjct: 1081 PGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGAS 1140
Query: 420 IRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNV 479
N G ++SP +P NY NN C + ++ G+ +++ LA+ D I D
Sbjct: 1141 ATN-NEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD-- 1197
Query: 480 EAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKY 539
+ + ++ + L S+ ++E ++D+ G G L Y +F+ HC +P +
Sbjct: 1198 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQ 1257
Query: 540 GNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEIT- 598
+ S + G+T+ + C+PGYTL GS +++C+ W+ P+C A C G
Sbjct: 1258 FGYKISDQGHFAGSTIIYGCNPGYTLH-GSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1316
Query: 599 DSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARV 658
+S+G +LSP +P PY C+W + V+ PG++++
Sbjct: 1317 ESSGRILSPGYPFPYDNNLRCMWMIEVD---------------PGNIVSLQ--------- 1352
Query: 659 LGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPN 718
+ F ++ +L G P ND L EI
Sbjct: 1353 --------------------FLAFDTEASHDILRVWDG-------PPENDML--LKEISG 1383
Query: 719 GWKSPSQPELVHGT--VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGD 776
PE +H T +VT Q + + S + + +S + T+C DPG
Sbjct: 1384 SLI----PEGIHSTLNIVTIQFDTDFYISKSG-----FAIQFSSSV-----ATACRDPGV 1429
Query: 777 VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLK 836
+ R + G TV + CD G+ L G +TC + W P C +
Sbjct: 1430 PMNGTR--NGDGREPGDTVVFQCDPGYELQGEERITCIQVE-NRYFWQPSPPVC----IA 1482
Query: 837 PCHG 840
PC G
Sbjct: 1483 PCGG 1486
Score = 139 bits (351), Expect = 1e-32
Identities = 172/749 (22%), Positives = 279/749 (37%), Gaps = 123/749 (16%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDV--GLDCFFYISVYPG---------YGVEIKVQNISL 292
C G G + SP S P + DC + I PG + +E K + +
Sbjct: 241 CGGTMRGSSGIISSP---SFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEI 297
Query: 293 REGETVTVEGLGGPDPLPLANQSFLLRGQVIRSPTHQ-----------AALRFQSLPPPA 341
E T+ G P P+ + LR + H+ A+ F+S
Sbjct: 298 EGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFKL 357
Query: 342 GPGTFHFHYQAYLLS---------CHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGA 392
PG + + + L C P P G + G + +F C Y L+GA
Sbjct: 358 FPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGA 417
Query: 393 RHLTCLNATQPF--WDSKEPVC-IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEA 449
+ +TC + F W PVC + CG ++ + G SP FP Y +N C W++ A
Sbjct: 418 KSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GTFTSPNFPFQYDSNAQCVWVITA 476
Query: 450 PEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAP-PVYDSYEVEYLPIEGLLSSGKHFFV 507
+ + ++FE+ L D L I +G V P V ++P + ++S ++
Sbjct: 477 VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVP-DLIVSMSSQMWL 535
Query: 508 ELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV--------GTTVEFSC 559
L TD S + G + Y+ ++ C +P TP Y + + F C
Sbjct: 536 HLQTDESVGSVGFKVNYKEIEKESCGDP---------GTPLYGIREGDGFSNRDVLRFEC 586
Query: 560 DPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDC 619
G+ L G I C + + QW+ P C C T G VLSP++PE YG +C
Sbjct: 587 QFGFEL-IGEKSIVCQE--NNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC 643
Query: 620 IWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADV 678
IW + + RI L + D L DGD + +LG ++G L ++ +
Sbjct: 644 IWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHIL 703
Query: 679 TIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIP-NGWKSPSQPELVHGTVVTYQ 737
++FQ+D S +GF I + N+ CP+ P IP N + +L G+ ++
Sbjct: 704 RLEFQADHSMS----GRGFNITYNTFGHNE-CPD-PGIPINARRFGDNFQL--GSSISVI 755
Query: 738 CYPGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSCHD------------PGDVEHSR 781
C G+ + G+ + C + WS +P C H PG + S
Sbjct: 756 CEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSL 815
Query: 782 RLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQ------AGSPKWSDRAPKCLLEQL 835
+ G +++ ++ + +L HD GS + P+ L
Sbjct: 816 NCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYN-GTQVPQFLFSSS 874
Query: 836 KPCHGLSAPENGARSPEKQLHPAGATIH---------------------------FSCAP 868
+ L +N + ++H T++ FSC
Sbjct: 875 NFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDS 934
Query: 869 GYVLKGQASIKCVPGHPSHWSDPPPICRA 897
GY L + + C H WS P P C A
Sbjct: 935 GYRLSHEEPLLCEKNH--WWSHPLPTCDA 961
Score = 127 bits (320), Expect = 4e-29
Identities = 138/569 (24%), Positives = 228/569 (40%), Gaps = 67/569 (11%)
Query: 244 CSWNFSGPEGSLDSPT-DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
C G G+++SP P G +C + I ++I Q+ +L E
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPN--GANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 122
Query: 303 LGGPDPLPLANQSFLLRGQVIRSPTHQA----ALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
G P P N L G + P +LR S + G ++ + SC
Sbjct: 123 DGHPHP---TNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Query: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL--NATQPFWDSKEPVCIA-- 414
P P G + T G R+ C TGY L G LTC+ + WD P+C A
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
ACGG +R ++ G I SP FP Y NN C W + A G + L F + E D L I
Sbjct: 240 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
Query: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQ------ 528
+ PP + P ++S+ + TDS+ G + Y+ +
Sbjct: 299 GSE----PPTIWLSGMNIPP--PIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKS 352
Query: 529 QGHCYEP---------FVKYGNFSSSTPTYP----------------VGTTVEFSCDPGY 563
+G P + G +++ P +G+TV+FSCD Y
Sbjct: 353 RGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDY 412
Query: 564 TLEQGSIIIEC--VDPHDPQWNETEPACRA-VCSGEITDSAGVVLSPNWPEPYGRGQDCI 620
L QG+ I C + W++ P C+ C + +G SPN+P Y C+
Sbjct: 413 VL-QGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCV 471
Query: 621 WGV-HVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL--TARVLGQYSGPRSHFKLFTSMA 676
W + V +K I ++ + G D LT DG ++ VL +G + + +
Sbjct: 472 WVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSS 531
Query: 677 DVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTY 736
+ + Q+D + GF +++ E+ + ++C + P P + + V+ +
Sbjct: 532 QMWLHLQTDESVGSV----GFKVNYKEIEK-ESCGD-PGTPL-YGIREGDGFSNRDVLRF 584
Query: 737 QCYPGYQVVGSSVLMCQWDLTWSEDLPSC 765
+C G++++G ++CQ + WS ++P C
Sbjct: 585 ECQFGFELIGEKSIVCQENNQWSANIPIC 613
Score = 104 bits (260), Expect = 4e-22
Identities = 104/410 (25%), Positives = 170/410 (41%), Gaps = 42/410 (10%)
Query: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
I CGG ++ G I SPGFP Y N C W++ A E R+ + F+ +L E+ D L
Sbjct: 62 IYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
Query: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
+ +G P + + + + S+ F + L++D + +A G + YE Q C
Sbjct: 121 LYDGH--PHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
Query: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV--DPHDPQWNETEPACR 590
P V T + VG + +SC GY L+ G + C+ + W+ P CR
Sbjct: 179 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILD-GHPQLTCIANSVNTASWDFPVPICR 236
Query: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML---DIRV------LR 639
A C G + S+G++ SP++P Y DC W + E I L D ++ L
Sbjct: 237 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLE 296
Query: 640 IGPGDVLTFY-DGDDLTARVLGQYSGPRSHF--------KLFTSMADV--TIQFQSDPGT 688
I + T + G ++ ++ + R HF + F++ V I F+S
Sbjct: 297 IEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKAIDFKSRGFK 356
Query: 689 SVLGYQQGFVIHFFE----VPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQV 744
G ++ CP+ E NG + S L G+ V + C Y +
Sbjct: 357 LFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSL--GSTVQFSCDEDYVL 414
Query: 745 VGSSVLMCQ----WDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
G+ + CQ WS+ P C +V +C +++ +SP FP
Sbjct: 415 QGAKSITCQRIAEVFAAWSDHRPVC-KVKTC--GSNLQGPSGTFTSPNFP 461
Score = 104 bits (260), Expect = 4e-22
Identities = 150/649 (23%), Positives = 239/649 (36%), Gaps = 108/649 (16%)
Query: 271 CFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPD---PLPLANQSFLLRGQVIRSPT 327
C + ISV GY + + V+ E E ++ GP+ P+ ++ I S
Sbjct: 2380 CAWSISVEKGYNITMFVEFFQT-EKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNG 2438
Query: 328 HQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDV-TVTSLHPGGSARFHCATG 386
H+ L++ + G F Y A+ C P P +G + + T R+ C G
Sbjct: 2439 HEVFLQWSADHGNNKKG-FRIRYIAFY--CSTPESPPHGYIISQTGGQLNSVVRWACDRG 2495
Query: 387 YQLKGARHLTCLNATQPF--WDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCH 444
++L G C ++ + WD+ P C A G+ + T G I++ + C+
Sbjct: 2496 FRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCN 2555
Query: 445 WLLEAPEGQRLHLHFEKVSLAEDDD---------RLIIRNGDNVEAPPVYDSYEVEYLPI 495
+G RL ++ + D R ++ + + PP + +
Sbjct: 2556 ------DGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVISCGELPTPPNGNK-----IGT 2604
Query: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ-------GHCYEPFVKYGNFSSSTPT 548
+ S F +L G+A L + + GHC P + N
Sbjct: 2605 QTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIV-NGQVIGEN 2663
Query: 549 YPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPN 608
Y TV + C+PG+ L S+ I C H+ W+ P+C V S G SP
Sbjct: 2664 YGYRDTVVYQCNPGFRLIGSSVRI-CQQDHN--WSGQLPSCVPV-------SCGHPGSPI 2713
Query: 609 WPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSH 668
+ G G + + +I L GP + Q+S P
Sbjct: 2714 YGRTSGNG------FNFNDVVTFSCNIGYLMQGPTKA---------QCQANRQWSHPPPM 2758
Query: 669 FKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPEL 728
K+ SDPG +P N E N
Sbjct: 2759 CKVVNC---------SDPG----------------IPANSKRESKIEHGN---------F 2784
Query: 729 VHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPK 788
+GTVV Y C PGY + GSSVL+CQ + W + LP C + C PG ++ ++S K
Sbjct: 2785 TYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMI-DCGHPGVPPNA--VLSGEK 2841
Query: 789 FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGA 848
+ G+TV Y C L+G S TC + WS P C + C P +G+
Sbjct: 2842 YTFGSTVHYSCTGKRSLLGQSSRTCQ----LNGHWSGSQPHCSGDATGTCGDPGTPGHGS 2897
Query: 849 RSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
R ++ +T+ ++C GY+L G C+ W+ P C+A
Sbjct: 2898 R--QESNFRTKSTVRYACDTGYILHGSEERTCLAN--GSWTGRQPECKA 2942
Score = 102 bits (254), Expect = 2e-21
Identities = 95/361 (26%), Positives = 151/361 (41%), Gaps = 19/361 (5%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
C N + G++ SP + DCF+ + V PG G+ I N ++ + E + +
Sbjct: 2179 CGGNITAMNGTIYSPGYPDEYPNFQ-DCFWLVRVPPGNGIYI---NFTVLQTEPIYDFIT 2234
Query: 302 GLGGPDP-LPLANQ-SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHF 359
GPD P Q S + + S ++Q ++F S G F Y AY L
Sbjct: 2235 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS--DFTTSGFFVLSYHAYQLRVCQ 2292
Query: 360 PRRPAYGDVTVTS---LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
P P +T G R+ C G+ L G LTC + D PVC C
Sbjct: 2293 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2352
Query: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
+R +TG I+SPG+P +Y N C W + +G + + E ++ D L + +
Sbjct: 2353 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2412
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
G N+++ PV S +Y + S+G F++ S D G +RY AF +C P
Sbjct: 2413 GPNIQS-PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTP 2468
Query: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL-EQGSIIIECVDPHDPQWNETEPACRAVCS 594
+ S + + V ++CD G+ L + S + W+ PAC+A+
Sbjct: 2469 ESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC 2528
Query: 595 G 595
G
Sbjct: 2529 G 2529
Score = 95.9 bits (237), Expect = 2e-19
Identities = 130/552 (23%), Positives = 194/552 (35%), Gaps = 144/552 (26%)
Query: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAA 415
+C P P +G ++ + R+ C TGY L G+ TCL W ++P C
Sbjct: 2886 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCL--ANGSWTGRQPEC--- 2940
Query: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
+ V G PG +N ++ +
Sbjct: 2941 -----------KAVQCGNPGTTANG-----------------------------KVFRID 2960
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
G + +Y +EG + SG ++G +G G P
Sbjct: 2961 GTTFSSSVIYSC-------MEGYILSGPSV---RQCTANGTWSGTLPNCTIISCGDPGIP 3010
Query: 536 F--VKYGNFSSSTPTYPVGTTVEFSCDPGYTLE-QGSIIIECVDPHDPQWNETEPACRAV 592
++YG+ Y VG V + C PGYT+E GS I C + W+ P CRAV
Sbjct: 3011 ANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSRIRTCT--INGTWSGVMPTCRAV 3062
Query: 593 -CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
C S G + N+ WG + PG L+F
Sbjct: 3063 TCPTPPQISNGRLEGTNFD----------WGFSIS-----------YICSPGYELSF--P 3099
Query: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
LT G +SG + +F DPG G ++G
Sbjct: 3100 AVLTCVGNGTWSG---------EVPQCLPKFCGDPGIPAQGKREG--------------- 3135
Query: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
++ + V++ C + +VGSS +CQ D TWS P C T
Sbjct: 3136 --------------KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3181
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
SC +PG H + ++ F VG+ VQ+ C +G +L GS+ TC WS P+
Sbjct: 3182 SCENPGVPRHGSQ-NNTFGFQVGSVVQFHCKKGHLLQGSTTRTC----LPDLTWSGIQPE 3236
Query: 830 CLLEQLKPCHGLSAPENGARS--PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
C+ H PE A + L G T+ ++C PG+ L G + V +
Sbjct: 3237 CI------PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNT 3289
Query: 888 WSDPPPICRAAS 899
W+ PIC A S
Sbjct: 3290 WTGKVPICEAGS 3301
Score = 74.7 bits (182), Expect = 4e-13
Identities = 55/191 (28%), Positives = 82/191 (42%), Gaps = 16/191 (8%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
+C ELP PNG K +Q +G+ + C G+ +VGS+V C WSE C
Sbjct: 2589 SCGELPTPPNGNKIGTQTS--YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL-A 2645
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
C P + + + + + TV Y C+ GF L+GSS+ C WS + P
Sbjct: 2646 GHCGIPELIVNGQ--VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQ----DHNWSGQLP 2699
Query: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
C+ C +P G S + FSC GY+++G +C W
Sbjct: 2700 SCVPVS---CGHPGSPIYGRTSGNG--FNFNDVVTFSCNIGYLMQGPTKAQCQANR--QW 2752
Query: 889 SDPPPICRAAS 899
S PPP+C+ +
Sbjct: 2753 SHPPPMCKVVN 2763
Score = 39.3 bits (90), Expect = 0.019
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 859 GATIHFSCAPGYVLKGQASIKCVPG--HPSHWSDPPPICRAASLDGFYNSRSLDVAKAPA 916
G I +SC GY+L G + C+ + + W P PICRA G S + +P+
Sbjct: 197 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPS 256
Score = 37.7 bits (86), Expect = 0.054
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
+SC +PG + ++ +F VG ++Y C G++L G LTC + W P
Sbjct: 176 SSCGNPG--VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
Query: 829 KCLLEQLKPCHGLSAPENGARS----PEKQLHPAGATIHFSCAPG 869
C E C G +G S P + + A T PG
Sbjct: 234 ICRAED--ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPG 276
Score = 33.5 bits (75), Expect = 1.0
Identities = 50/237 (21%), Positives = 85/237 (35%), Gaps = 63/237 (26%)
Query: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPVCI 413
++C P + + G + T+ G S + C+ GY+L LTC+ N T W + P C+
Sbjct: 3062 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3118
Query: 414 AA-CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
CG PG P EG+ ++ +VS + + ++
Sbjct: 3119 PKFCG------------DPGIPAQGKR-----------EGKSF-IYQSEVSFSCNFPFIL 3154
Query: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
+ + + +G S +E + S C
Sbjct: 3155 VGSSTRI-------------CQADGTWSGSSPHCIEPTQTS------------------C 3183
Query: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
P V ++T + VG+ V+F C G+ L QGS C+ D W+ +P C
Sbjct: 3184 ENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLL-QGSTTRTCLP--DLTWSGIQPEC 3237
>gi|38045888 CUB and Sushi multiple domains 3 isoform 1 [Homo sapiens]
Length = 3707
Score = 233 bits (594), Expect = 7e-61
Identities = 157/514 (30%), Positives = 240/514 (46%), Gaps = 16/514 (3%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
PC + +G++ SP P D L+C + I+V G G++++V + +
Sbjct: 1938 PCGGILTKRKGTILSP-GYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFY 1996
Query: 303 LGGPDPLP-LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFP 360
GG + P L + S ++ S ++ L FQS + G FH Y A L SC P
Sbjct: 1997 DGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAG-FHLEYTAIGLDSCPEP 2055
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVI 420
+ P+ G G F C GY L+G H+TC+ W+ P+C+A CGG +
Sbjct: 2056 QTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAM 2115
Query: 421 RNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVE 480
+ + G I+SPGFPGNY ++L C W + P G +HL F S D L +R+G + E
Sbjct: 2116 SDFS-GVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSS-E 2173
Query: 481 APPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
V +P L S+ + +D S G + Y+A+Q C +P
Sbjct: 2174 TSTVIGRLSGPQIP-SSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRN 2232
Query: 541 NFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDS 600
F + VG T+ F C PGYTL G+ + C+ WN P C A+C G IT
Sbjct: 2233 GFVIGND-FTVGQTISFECFPGYTLI-GNSALTCLHGVSRNWNHPLPRCEALCGGNITAM 2290
Query: 601 AGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGP-GDVLTFYDGDDLTARVL 659
G + SP +P+ Y QDC W V V I ++ VL+ P D +T +DG D + +
Sbjct: 2291 NGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI 2350
Query: 660 GQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNG 719
GQ+SG + ++++ + I+F SD TS GF + + + C P +PN
Sbjct: 2351 GQFSGNTALESVYSTSNQILIKFHSDFTTS------GFFVLSYHAYQLRVCQPPPPVPNA 2404
Query: 720 WKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQ 753
E G ++ YQC PG+ +VG+++L C+
Sbjct: 2405 EILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCR 2438
Score = 224 bits (570), Expect = 4e-58
Identities = 180/614 (29%), Positives = 265/614 (43%), Gaps = 37/614 (6%)
Query: 203 GAGIGIQGTITSSTASGDDEETTTTTTIITTTITTVQTPGP-----CSWNFSGPEGSLDS 257
G GI T+T S +SG E T+ + P P C + + EG L S
Sbjct: 1195 GFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLS 1254
Query: 258 PTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-EGLGGPDPLPLANQSF 316
P + + +C + I V G G+ I + L +G+ + + +G L A
Sbjct: 1255 P-NYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGA 1313
Query: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFPRRPAYGDVTVTSLHP 375
+RG + S ++Q L F S G F Y ++ LS C P P +G H
Sbjct: 1314 SMRGLTLSSTSNQLWLEFNSDTEGTDEG-FQLVYTSFELSHCEDPGIPQFGYKISDQGHF 1372
Query: 376 GGSARFH-CATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFP 434
GS + C GY L G+ L C+ + WD P CIA CGG + ++GRI+SPG+P
Sbjct: 1373 AGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYP 1432
Query: 435 GNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEY-- 492
Y NNL C W++E G + L F D L + +G PP D E
Sbjct: 1433 FPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDG-----PPENDMLLKEISG 1487
Query: 493 -LPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPV 551
L EG+ S+ ++ TD + +G A+++ + C +P V + P
Sbjct: 1488 SLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREP- 1546
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQ-WNETEPACRAVCSGEITDSAGVVLSPNWP 610
G TV F CDPGY L QG I C+ + W + P C A C G +T S+G +LSPN+P
Sbjct: 1547 GDTVVFQCDPGYEL-QGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFP 1605
Query: 611 EPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGPRSHF 669
PY +DC W + V D I L I P D L YDG D + ++G + +
Sbjct: 1606 HPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPE 1665
Query: 670 KLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELV 729
++ +S + + F+SD S G+ ++ ++C + I NG + +L
Sbjct: 1666 RIESSSNTMHLAFRSDGSVSYTGFHLE-----YKAKLRESCFDPGNIMNGTRLGMDYKL- 1719
Query: 730 HGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
G+ VTY C GY + G S L C W+ LPSC G S +
Sbjct: 1720 -GSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTG----SEGTVL 1774
Query: 786 SPKFPVGATVQYIC 799
SP +P +V + C
Sbjct: 1775 SPNYPKNYSVGHNC 1788
Score = 219 bits (559), Expect = 8e-57
Identities = 182/653 (27%), Positives = 289/653 (44%), Gaps = 51/653 (7%)
Query: 269 LDCFFYISVYPGYGVEIKVQNIS---------LREG--ETVTVEG-LGGPDPLPLANQSF 316
LDC + I++ G+GV ++ N S +R G ET TV G L GP +P +
Sbjct: 2135 LDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQ-IPSS---- 2189
Query: 317 LLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHFPRRPAYGDVTVTSLHP 375
+ S TH+ +L F S G FH YQAY L SC PR G V
Sbjct: 2190 ------LFSTTHETSLYFHSDYSQNKQG-FHIVYQAYQLQSCPDPRPFRNGFVIGNDFTV 2242
Query: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPG 435
G + F C GY L G LTCL+ W+ P C A CGG I A G I SPG+P
Sbjct: 2243 GQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNI-TAMNGTIYSPGYPD 2301
Query: 436 NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPI 495
Y N C WL+ P G ++++F + D + + +G + +P + +
Sbjct: 2302 EYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI--GQFSGNTAL 2359
Query: 496 EGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPF-VKYGNFSSSTPTYPVGTT 554
E + S+ ++ +D + + L Y A+Q C P V + + +G
Sbjct: 2360 ESVYSTSNQILIKFHSDFT-TSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDI 2418
Query: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC-SGEIT-DSAGVVLSPNWPEP 612
+ + C PG+TL G+ I+ C Q + P C+ +C + E+ DS GV+LSP +P+
Sbjct: 2419 IRYQCLPGFTLV-GNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDS 2477
Query: 613 YGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDLTARVLGQYSGP-RSHFK 670
Y Q C W + VE+ I + + + DVL YDG ++ + VL SG S F
Sbjct: 2478 YPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFN 2537
Query: 671 LFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH 730
+ ++ +V +Q+ +D G + G++ ++ + P + P+G+ SQ
Sbjct: 2538 ITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESP--------PHGY-IISQTGGQL 2588
Query: 731 GTVVTYQCYPGYQVVGSSVLMCQWDL----TWSEDLPSCQRVTSCHDPGDVEHSRRLISS 786
+VV + C G+++VG S +C+ W +P+CQ + SC P + I +
Sbjct: 2589 NSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAI-SCGIPKAPTNGG--ILT 2645
Query: 787 PKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPEN 846
+ VG V Y C+ G+ L + T + G+ ++ P+C++ +
Sbjct: 2646 TDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHG 2705
Query: 847 GARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
R + + FSC PGY G ASI+C+P W + P C+ S
Sbjct: 2706 RWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIIS 2758
Score = 206 bits (525), Expect = 7e-53
Identities = 191/713 (26%), Positives = 293/713 (41%), Gaps = 78/713 (10%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
PC +FS P G + SP D L+C + I PG+ ++I + V +E
Sbjct: 894 PCGGHFSAPSGVILSPGWPGYYKD-SLNCEWVIEAEPGHSIKITFERFQTELNYDV-LEV 951
Query: 303 LGGPDPLP--LANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL---SC 357
GP+ L L + + Q + S ++ L F + + G F HY++ + SC
Sbjct: 952 HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNG-FKIHYESVTVNTYSC 1010
Query: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
P P +G G + F C +GY+L L C +W P C A CG
Sbjct: 1011 LDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC--EKNHWWSHPLPTCDALCG 1068
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
G +R + G I+SPG+P Y N+L C W ++ G+ + +F L + D L+I
Sbjct: 1069 GDVRGPS-GTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENG 1127
Query: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFV 537
+ P + I L + +D S + G + + + C +P +
Sbjct: 1128 SFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGI 1187
Query: 538 -KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGE 596
+YG S + +G T+ FSC GY LE S II C+ W+ P C A C
Sbjct: 1188 PQYG--SRIGFNFGIGDTLTFSCSSGYRLEGTSEII-CLGGGRRVWSAPLPRCVAECGAS 1244
Query: 597 ITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTA 656
T++ G++LSPN+P Y +CI+ + V+ K I + R + GDVL YDG D T
Sbjct: 1245 ATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTT 1304
Query: 657 RVLGQYSGPRSHFKLFTSMAD-VTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPE 715
+LG ++G +S ++ + ++F SD + G+Q V FE+ + P +P+
Sbjct: 1305 HLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQ--LVYTSFELSHCED-PGIPQ 1361
Query: 716 IPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSCQRVTSCHD 773
G+K Q T++ Y C PGY + GSS+L C W LPSC + C
Sbjct: 1362 F--GYKISDQGHFAGSTII-YGCNPGYTLHGSSLLKCMTGERRAWDYPLPSC--IAECGG 1416
Query: 774 PGDVEHSRRLISSPKFPVGATVQYIC------DQGFVL----MGSSILTCHD--RQAGSP 821
E S R++S P +P C D G ++ + HD R P
Sbjct: 1417 RFKGESSGRILS-PGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGP 1475
Query: 822 KWSDRAPKCLLEQLKP------------------------------------CHGLSAPE 845
+D K + L P C P
Sbjct: 1476 PENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPM 1535
Query: 846 NGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH-WSDPPPICRA 897
NG R+ + + G T+ F C PGY L+G+ I C+ + W PP+C A
Sbjct: 1536 NGTRNGDGR--EPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIA 1586
Score = 190 bits (482), Expect = 7e-48
Identities = 152/556 (27%), Positives = 234/556 (42%), Gaps = 28/556 (5%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYIS-VYPGYGVEIKVQNISLREGETVTVEG 302
C N GP G+ SP + D C + I+ V ++I + L G G
Sbjct: 548 CGSNLQGPSGTFTSP-NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIG 606
Query: 303 LGGP--DP---LPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSC 357
GG DP L + SF+ +I S + Q L Q+ G + + SC
Sbjct: 607 DGGEVGDPRTVLQVLTGSFV--PDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESC 664
Query: 358 HFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACG 417
P P YG RF C G++L G + + C Q W + P+CI C
Sbjct: 665 GDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQ--WSANIPICIFPCL 722
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGD 477
A G ++SP +P Y NNL C W + + G R+HL F L D L +++GD
Sbjct: 723 SNF-TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGD 781
Query: 478 NVEAPPVYDSYEVEYLPIEGLLSSGKHFF-VELSTDSSGAAAGMALRYEAFQQGHCYEPF 536
+ E+ P+ ++ +P L+S H +E D S + G + Y F C +P
Sbjct: 782 SPES-PILGTFTGAEVPSH--LTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPG 838
Query: 537 VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV-DPHDPQWNETEPACRAVCSG 595
+ N + +G+++ C+ G+ QG+ I C+ W+ P C A C G
Sbjct: 839 IPI-NARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 897
Query: 596 EITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDGDDL 654
+ +GV+LSP WP Y +C W + E I + + DVL +DG +L
Sbjct: 898 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 957
Query: 655 TARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELP 714
+ +LG Y+G + LF+S + + F +D S GF IH+ V N P
Sbjct: 958 LSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRS----NNGFKIHYESVTVNTYSCLDP 1013
Query: 715 EIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDP 774
IP + + G+ V++ C GY++ L+C+ + WS LP+C +
Sbjct: 1014 GIPVHGRRYGH-DFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCG---- 1068
Query: 775 GDVEHSRRLISSPKFP 790
GDV I SP +P
Sbjct: 1069 GDVRGPSGTILSPGYP 1084
Score = 184 bits (467), Expect = 4e-46
Identities = 186/717 (25%), Positives = 300/717 (41%), Gaps = 86/717 (11%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLR-EGETVTVE 301
PC NF+ P G++ SP D L+C + I PG + + + L + + + V+
Sbjct: 720 PCLSNFTAPMGTVLSP-DYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVK 778
Query: 302 GLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLS-CHFP 360
P+ L + + S +H L FQ+ +G G F+ Y + + C P
Sbjct: 779 DGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRG-FNITYNTFGHNECPDP 837
Query: 361 RRPAYGDVTVTSLHPGGSARFHCATGY-QLKGARHLTC-LNATQPFWDSKEPVCIAACGG 418
P + G S C G+ + +G +TC L + W P C A CGG
Sbjct: 838 GIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 897
Query: 419 VIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN 478
+A +G I+SPG+PG Y ++L C W++EA G + + FE+ + D L + +G N
Sbjct: 898 HF-SAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPN 956
Query: 479 VEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--HCYEPF 536
+ +P + SY +P + L SS ++ +TD+S + G + YE+ C +P
Sbjct: 957 LLSP-LLGSYNGTQVP-QFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG 1014
Query: 537 V-----KYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
+ +YG+ + +G+TV FSCD GY L ++ C H W+ P C A
Sbjct: 1015 IPVHGRRYGH------DFSIGSTVSFSCDSGYRLSHEEPLL-CEKNH--WWSHPLPTCDA 1065
Query: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYD 650
+C G++ +G +LSP +PE Y +C W V V K + + + D L +
Sbjct: 1066 LCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1125
Query: 651 GDDLT---ARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
T AR+ G P + L+ + ++F SD S +GF I F E
Sbjct: 1126 NGSFTQPLARLTGSDLPPTINAGLYGNFR-AQLRFISDFSISY----EGFNITFSEY-NL 1179
Query: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSEDLPSC 765
+ C + P IP + S G +T+ C GY++ G+S ++C WS LP C
Sbjct: 1180 EPCED-PGIPQ-YGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRC 1237
Query: 766 QR------------VTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTC 813
+ S + P + E++ I S + G + I + F L +L
Sbjct: 1238 VAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGIN-ISARTFHLAQGDVLKI 1296
Query: 814 HDRQAGSPKW--------------SDRAPKCLLE-------------------QLKPCHG 840
+D + + S + + LE +L C
Sbjct: 1297 YDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCED 1356
Query: 841 LSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
P+ G + + Q H AG+TI + C PGY L G + +KC+ G W P P C A
Sbjct: 1357 PGIPQFGYKISD-QGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIA 1412
Score = 183 bits (465), Expect = 6e-46
Identities = 197/723 (27%), Positives = 292/723 (40%), Gaps = 96/723 (13%)
Query: 243 PCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTV-- 300
PC N +G G + SP + P DC + I+V Y + + + S+
Sbjct: 1587 PCGGNLTGSSGFILSP-NFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIY 1645
Query: 301 EGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLL-SCHF 359
+G PL + Q L + I S ++ L F+S + G FH Y+A L SC
Sbjct: 1646 DGPDSNSPLIGSFQDSKLPER-IESSSNTMHLAFRSDGSVSYTG-FHLEYKAKLRESCFD 1703
Query: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNAT--QPFWDSKEPVCIAACG 417
P G G + ++C GY L+G LTC+ +P W+ P C A CG
Sbjct: 1704 PGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCG 1763
Query: 418 GVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPE-----GQRLHLHFEKVSLAEDDDRLI 472
+ G ++SP +P NYS C + + P+ GQ + F + SL D +
Sbjct: 1764 SR-STGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFV---FFQTSL---HDVVE 1816
Query: 473 IRNGDNVEAP---PVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
+ +G ++ + S+ E LP LSSG + ++ A G Y+A +
Sbjct: 1817 VYDGPTQQSSLLSSLSGSHSGESLP----LSSGNQITIRFTSVGPITAKGFHFVYQAVPR 1872
Query: 530 GHCYE----PFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIEC--VDPHDPQWN 583
+ P ++G + + VG++V F C+PGY L GSI I C V QWN
Sbjct: 1873 TSSTQCSSVPEPRFGRRIGNE--FAVGSSVLFDCNPGYILH-GSIAIRCETVPNSLAQWN 1929
Query: 584 ETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG 643
++ P C C G +T G +LSP +PEPY +C+W + V E I + +
Sbjct: 1930 DSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHN 1989
Query: 644 -DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
D L FYDG D A LG YSG L ++ ++ + FQSD S G+ +
Sbjct: 1990 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 2049
Query: 703 EVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD--LTWSE 760
D+CPE P+ P+ +V G VV++QC GY + G S + C W+
Sbjct: 2050 -----DSCPE-PQTPSSGIKIGDRYMV-GDVVSFQCDQGYSLQGHSHITCMPGPVRRWNY 2102
Query: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQ------GF----VLMGSSI 810
+P C + C G + +I SP FP C GF + S
Sbjct: 2103 PIPIC--LAQC--GGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFST 2158
Query: 811 LTCHDR---QAGSPKWSD-----RAPKCLLEQLKPCHGLSAPENGARSPEKQ-LH----- 856
T HD ++GS + S P+ H S + S KQ H
Sbjct: 2159 ETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA 2218
Query: 857 ----------------------PAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPI 894
G TI F C PGY L G +++ C+ G +W+ P P
Sbjct: 2219 YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPR 2278
Query: 895 CRA 897
C A
Sbjct: 2279 CEA 2281
Score = 153 bits (387), Expect = 7e-37
Identities = 146/604 (24%), Positives = 242/604 (40%), Gaps = 87/604 (14%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGL 303
C + GP G++ SP + L+C + + V G GV+ L + +
Sbjct: 1067 CGGDVRGPSGTILSPGYPEFYPN-SLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITE 1125
Query: 304 GGPDPLPLANQSFLLRGQVIRSPTH---QAALRFQSLPPPAGPGTFHFHYQAYLLS-CHF 359
G PLA + I + + +A LRF S + G F+ + Y L C
Sbjct: 1126 NGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEG-FNITFSEYNLEPCED 1184
Query: 360 PRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGV 419
P P YG + G + F C++GY+L+G + CL + W + P C+A CG
Sbjct: 1185 PGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGAS 1244
Query: 420 IRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNV 479
N G ++SP +P NY NN C + ++ G+ +++ LA+ D I D
Sbjct: 1245 ATN-NEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKD-- 1301
Query: 480 EAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKY 539
+ + ++ + L S+ ++E ++D+ G G L Y +F+ HC +P +
Sbjct: 1302 KTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQ 1361
Query: 540 GNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEIT- 598
+ S + G+T+ + C+PGYTL GS +++C+ W+ P+C A C G
Sbjct: 1362 FGYKISDQGHFAGSTIIYGCNPGYTLH-GSSLLKCMTGERRAWDYPLPSCIAECGGRFKG 1420
Query: 599 DSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARV 658
+S+G +LSP +P PY C+W + V+ PG++++
Sbjct: 1421 ESSGRILSPGYPFPYDNNLRCMWMIEVD---------------PGNIVSLQ--------- 1456
Query: 659 LGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPN 718
+ F ++ +L G P ND L EI
Sbjct: 1457 --------------------FLAFDTEASHDILRVWDG-------PPENDML--LKEISG 1487
Query: 719 GWKSPSQPELVHGT--VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGD 776
PE +H T +VT Q + + S + + +S + T+C DPG
Sbjct: 1488 SLI----PEGIHSTLNIVTIQFDTDFYISKSG-----FAIQFSSSV-----ATACRDPGV 1533
Query: 777 VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLK 836
+ R + G TV + CD G+ L G +TC + W P C +
Sbjct: 1534 PMNGTR--NGDGREPGDTVVFQCDPGYELQGEERITCIQVE-NRYFWQPSPPVC----IA 1586
Query: 837 PCHG 840
PC G
Sbjct: 1587 PCGG 1590
Score = 137 bits (344), Expect = 7e-32
Identities = 179/771 (23%), Positives = 289/771 (37%), Gaps = 136/771 (17%)
Query: 211 TITSSTASGDDEETTTTTTIITTTITTVQTPGPCSWNFSGPEGSLDSPTDLSSPTDVGLD 270
T+T +T++G+ EE TTT +T P DV +
Sbjct: 347 TLTHTTSTGELEEHNRTTTGAIAVAST--------------------------PADVTVS 380
Query: 271 CFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRG----QVIRSP 326
++++ E +VQ SLR G P P QS R Q+ R+
Sbjct: 381 SVTAVTIHR-LSEEQRVQVTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTK 439
Query: 327 -----THQA--ALRFQSLPPPAGPGTFHFHYQAYLLS---------CHFPRRPAYGDVTV 370
TH+ A+ F+S PG + + + L C P P G
Sbjct: 440 ELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIG 499
Query: 371 TSLHPGGSARFHCATGYQLKGARHLTCLNATQPF--WDSKEPVC-IAACGGVIRNATTGR 427
+ G + +F C Y L+GA+ +TC + F W PVC + CG ++ + G
Sbjct: 500 SDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPS-GT 558
Query: 428 IVSPGFPGNYSNNLTCHWLLEAPEGQR-LHLHFEKVSLAEDDDRLIIRNGDNVEAP-PVY 485
SP FP Y +N C W++ A + + ++FE+ L D L I +G V P V
Sbjct: 559 FTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVL 618
Query: 486 DSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSS 545
++P + ++S ++ L TD S + G + Y+ ++ C +P
Sbjct: 619 QVLTGSFVP-DLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDP---------G 668
Query: 546 TPTYPV--------GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEI 597
TP Y + + F C G+ L G I C + + QW+ P C C
Sbjct: 669 TPLYGIREGDGFSNRDVLRFECQFGFEL-IGEKSIVCQE--NNQWSANIPICIFPCLSNF 725
Query: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRI-GPGDVLTFYDGDDLTA 656
T G VLSP++PE YG +CIW + + RI L + D L DGD +
Sbjct: 726 TAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPES 785
Query: 657 RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEI 716
+LG ++G L ++ + ++FQ+D S +GF I + N+ CP+ P I
Sbjct: 786 PILGTFTGAEVPSHLTSNSHILRLEFQADHSMS----GRGFNITYNTFGHNE-CPD-PGI 839
Query: 717 P-NGWKSPSQPELVHGTVVTYQCYPGY-QVVGSSVLMC---QWDLTWSEDLPSCQRVTSC 771
P N + +L G+ ++ C G+ + G+ + C + WS +P C
Sbjct: 840 PINARRFGDNFQL--GSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGG 897
Query: 772 HD------------PGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQ-- 817
H PG + S + G +++ ++ + +L HD
Sbjct: 898 HFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNL 957
Query: 818 ----AGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIH---------- 863
GS + P+ L + L +N + ++H T++
Sbjct: 958 LSPLLGSYN-GTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP 1016
Query: 864 -----------------FSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
FSC GY L + + C H WS P P C A
Sbjct: 1017 VHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNH--WWSHPLPTCDA 1065
Score = 102 bits (254), Expect = 2e-21
Identities = 95/361 (26%), Positives = 151/361 (41%), Gaps = 19/361 (5%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVT--VE 301
C N + G++ SP + DCF+ + V PG G+ I N ++ + E + +
Sbjct: 2283 CGGNITAMNGTIYSPGYPDEYPNFQ-DCFWLVRVPPGNGIYI---NFTVLQTEPIYDFIT 2338
Query: 302 GLGGPDP-LPLANQ-SFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHF 359
GPD P Q S + + S ++Q ++F S G F Y AY L
Sbjct: 2339 VWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHS--DFTTSGFFVLSYHAYQLRVCQ 2396
Query: 360 PRRPAYGDVTVTS---LHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAAC 416
P P +T G R+ C G+ L G LTC + D PVC C
Sbjct: 2397 PPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLC 2456
Query: 417 -GGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
+R +TG I+SPG+P +Y N C W + +G + + E ++ D L + +
Sbjct: 2457 PANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD 2516
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
G N+++ PV S +Y + S+G F++ S D G +RY AF +C P
Sbjct: 2517 GPNIQS-PVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAF---YCSTP 2572
Query: 536 FVKYGNFSSSTPTYPVGTTVEFSCDPGYTL-EQGSIIIECVDPHDPQWNETEPACRAVCS 594
+ S + + V ++CD G+ L + S + W+ PAC+A+
Sbjct: 2573 ESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISC 2632
Query: 595 G 595
G
Sbjct: 2633 G 2633
Score = 99.0 bits (245), Expect = 2e-20
Identities = 66/225 (29%), Positives = 103/225 (45%), Gaps = 9/225 (4%)
Query: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
I CGG ++ G I SPGFP Y N C W++ A E R+ + F+ +L E+ D L
Sbjct: 62 IYTCGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLS 120
Query: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
+ +G P + + + + S+ F + L++D + +A G + YE Q C
Sbjct: 121 LYDGH--PHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSC 178
Query: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECV--DPHDPQWNETEPACR 590
P V T + VG + +SC GY L+ G + C+ + W+ P CR
Sbjct: 179 GNPGVPPKGVLYGT-RFDVGDKIRYSCVTGYILD-GHPQLTCIANSVNTASWDFPVPICR 236
Query: 591 A--VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML 633
A C G + S+G++ SP++P Y DC W + E I L
Sbjct: 237 AEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISL 281
Score = 95.9 bits (237), Expect = 2e-19
Identities = 130/552 (23%), Positives = 194/552 (35%), Gaps = 144/552 (26%)
Query: 356 SCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAA 415
+C P P +G ++ + R+ C TGY L G+ TCL W ++P C
Sbjct: 3055 TCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCL--ANGSWTGRQPEC--- 3109
Query: 416 CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
+ V G PG +N ++ +
Sbjct: 3110 -----------KAVQCGNPGTTANG-----------------------------KVFRID 3129
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEP 535
G + +Y +EG + SG ++G +G G P
Sbjct: 3130 GTTFSSSVIYSC-------MEGYILSGPSV---RQCTANGTWSGTLPNCTIISCGDPGIP 3179
Query: 536 F--VKYGNFSSSTPTYPVGTTVEFSCDPGYTLE-QGSIIIECVDPHDPQWNETEPACRAV 592
++YG+ Y VG V + C PGYT+E GS I C + W+ P CRAV
Sbjct: 3180 ANGLRYGD------DYVVGQNVSYMCQPGYTMELNGSRIRTCT--INGTWSGVMPTCRAV 3231
Query: 593 -CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
C S G + N+ WG + PG L+F
Sbjct: 3232 TCPTPPQISNGRLEGTNFD----------WGFSIS-----------YICSPGYELSF--P 3268
Query: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
LT G +SG + +F DPG G ++G
Sbjct: 3269 AVLTCVGNGTWSG---------EVPQCLPKFCGDPGIPAQGKREG--------------- 3304
Query: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--QRVT 769
++ + V++ C + +VGSS +CQ D TWS P C T
Sbjct: 3305 --------------KSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT 3350
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
SC +PG H + ++ F VG+ VQ+ C +G +L GS+ TC WS P+
Sbjct: 3351 SCENPGVPRHGSQ-NNTFGFQVGSVVQFHCKKGHLLQGSTTRTC----LPDLTWSGIQPE 3405
Query: 830 CLLEQLKPCHGLSAPENGARS--PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
C+ H PE A + L G T+ ++C PG+ L G + V +
Sbjct: 3406 CI------PHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHR-VCRSDNT 3458
Query: 888 WSDPPPICRAAS 899
W+ PIC A S
Sbjct: 3459 WTGKVPICEAGS 3470
Score = 95.1 bits (235), Expect = 3e-19
Identities = 138/570 (24%), Positives = 204/570 (35%), Gaps = 115/570 (20%)
Query: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDS--KEPVC 412
+SC P+ P G + T G + C GY+L T + + W + K P C
Sbjct: 2630 ISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRC 2689
Query: 413 IAA-CGGV---IRNATTGRIVS---------------PGFPGNYSNNLTC------HWLL 447
+ C + I RIV+ PG+ G ++ C W
Sbjct: 2690 VVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRN 2749
Query: 448 EAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFV 507
E P + + +S E NG+ + Y S + + G + G
Sbjct: 2750 ERP-------YCQIISCGELPTP---PNGNKIGTQTSYGSTAIFTCDL-GFMLVGSAVRE 2798
Query: 508 ELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQ 567
LS SG + R A GHC P + N Y TV + C+PG+ L
Sbjct: 2799 CLS---SGLWSESETRCLA---GHCGIPELIV-NGQVIGENYGYRDTVVYQCNPGFRLIG 2851
Query: 568 GSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEE 627
S+ I C H+ W+ P+C V S G SP + G G + +
Sbjct: 2852 SSVRI-CQQDHN--WSGQLPSCVPV-------SCGHPGSPIYGRTSGNG------FNFND 2895
Query: 628 DKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPG 687
+I L GP + Q+S P K+ SDPG
Sbjct: 2896 VVTFSCNIGYLMQGPTKA---------QCQANRQWSHPPPMCKVVNC---------SDPG 2937
Query: 688 TSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGS 747
+P N E N +GTVV Y C PGY + GS
Sbjct: 2938 ----------------IPANSKRESKIEHGN---------FTYGTVVFYDCNPGYFLFGS 2972
Query: 748 SVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMG 807
SVL+CQ + W + LP C + C PG ++ ++S K+ G+TV Y C L+G
Sbjct: 2973 SVLICQPNGQWDKPLPECIMI-DCGHPGVPPNA--VLSGEKYTFGSTVHYSCTGKRSLLG 3029
Query: 808 SSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCA 867
S TC + WS P C + C P +G+R ++ +T+ ++C
Sbjct: 3030 QSSRTCQ----LNGHWSGSQPHCSGDATGTCGDPGTPGHGSR--QESNFRTKSTVRYACD 3083
Query: 868 PGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
GY+L G C+ W+ P C+A
Sbjct: 3084 TGYILHGSEERTCLAN--GSWTGRQPECKA 3111
Score = 86.7 bits (213), Expect = 1e-16
Identities = 153/607 (25%), Positives = 217/607 (35%), Gaps = 141/607 (23%)
Query: 354 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
++SC P G+ T G +A F C G+ L G+ CL++ W E C+
Sbjct: 2756 IISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSS--GLWSESETRCL 2813
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
A G+ G+++ + Y + + + + G R L V + + D
Sbjct: 2814 AGHCGIPELIVNGQVIGENY--GYRDTV----VYQCNPGFR--LIGSSVRICQQDHNW-- 2863
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG--- 530
+G PV + PI G S F ++ T S M +A Q
Sbjct: 2864 -SGQLPSCVPVSCGHPGS--PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQ 2920
Query: 531 -----------HCYEP----------FVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGS 569
+C +P +++GNF TY GT V + C+PGY L S
Sbjct: 2921 WSHPPPMCKVVNCSDPGIPANSKRESKIEHGNF-----TY--GTVVFYDCNPGYFLFGSS 2973
Query: 570 IIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVE-ED 628
++I P+ QW++ P C + G VLS E Y G VH
Sbjct: 2974 VLI--CQPNG-QWDKPLPECIMIDCGHPGVPPNAVLS---GEKYTFGST----VHYSCTG 3023
Query: 629 KRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGT 688
KR +L T ++ G +SG + H D T DPGT
Sbjct: 3024 KRSLL----------------GQSSRTCQLNGHWSGSQPH-----CSGDAT-GTCGDPGT 3061
Query: 689 SVLGYQQ----------------GFVIHFFEVPRNDTCPELPEIPNGWKSPSQPEL---- 728
G +Q G+++H E TC + NG + QPE
Sbjct: 3062 PGHGSRQESNFRTKSTVRYACDTGYILHGSE---ERTC-----LANGSWTGRQPECKAVQ 3113
Query: 729 --------------VHGTV----VTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTS 770
+ GT V Y C GY + G SV C + TWS LP+C + S
Sbjct: 3114 CGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNC-TIIS 3172
Query: 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFV--LMGSSILTCHDRQAGSPKWSDRAP 828
C DPG + R + VG V Y+C G+ L GS I TC + WS P
Sbjct: 3173 CGDPGIPANGLRY--GDDYVVGQNVSYMCQPGYTMELNGSRIRTC----TINGTWSGVMP 3226
Query: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
C + C NG E G +I + C+PGY L A + CV W
Sbjct: 3227 TC---RAVTCPTPPQISNGRL--EGTNFDWGFSISYICSPGYELSFPAVLTCVGN--GTW 3279
Query: 889 SDPPPIC 895
S P C
Sbjct: 3280 SGEVPQC 3286
Score = 79.3 bits (194), Expect = 2e-14
Identities = 79/291 (27%), Positives = 114/291 (39%), Gaps = 21/291 (7%)
Query: 244 CSWNFSGPEGSLDSPT-DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEG 302
C G G+++SP P G +C + I ++I Q+ +L E
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPN--GANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLY 122
Query: 303 LGGPDPLPLANQSFLLRGQVIRSPTHQA----ALRFQSLPPPAGPGTFHFHYQAYLLSCH 358
G P P N L G + P +LR S + G ++ + SC
Sbjct: 123 DGHPHP---TNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCG 179
Query: 359 FPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL--NATQPFWDSKEPVCIA-- 414
P P G + T G R+ C TGY L G LTC+ + WD P+C A
Sbjct: 180 NPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAED 239
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIR 474
ACGG +R ++ G I SP FP Y NN C W + A G + L F + E D L I
Sbjct: 240 ACGGTMRGSS-GIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIE 298
Query: 475 NGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYE 525
+ PP + P ++S+ + TDS+ G + Y+
Sbjct: 299 GSE----PPTIWLSGMNIPP--PIISNKNWLRLHFVTDSNHRYRGFSAPYQ 343
Score = 74.7 bits (182), Expect = 4e-13
Identities = 55/191 (28%), Positives = 82/191 (42%), Gaps = 16/191 (8%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
+C ELP PNG K +Q +G+ + C G+ +VGS+V C WSE C
Sbjct: 2758 SCGELPTPPNGNKIGTQTS--YGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCL-A 2814
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
C P + + + + + TV Y C+ GF L+GSS+ C WS + P
Sbjct: 2815 GHCGIPELIVNGQ--VIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDH----NWSGQLP 2868
Query: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHW 888
C+ C +P G S + FSC GY+++G +C W
Sbjct: 2869 SCVPVS---CGHPGSPIYGRTSGNG--FNFNDVVTFSCNIGYLMQGPTKAQCQANR--QW 2921
Query: 889 SDPPPICRAAS 899
S PPP+C+ +
Sbjct: 2922 SHPPPMCKVVN 2932
Score = 58.5 bits (140), Expect = 3e-08
Identities = 48/203 (23%), Positives = 86/203 (42%), Gaps = 14/203 (6%)
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-DVLTFYDG 651
C G + G + SP +P Y G +C W + EE RI + + + D L+ YDG
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDG 124
Query: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCP 711
+ +G + ++ + +++ SD S G++ ++E ++ +C
Sbjct: 125 HPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKV-----YYEELQSSSCG 179
Query: 712 ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD----LTWSEDLPSCQR 767
P G ++ ++ G + Y C GY + G L C + +W +P C+
Sbjct: 180 NPGVPPKGVLYGTRFDV--GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRA 237
Query: 768 VTSCHDPGDVEHSRRLISSPKFP 790
+C G + S +ISSP FP
Sbjct: 238 EDAC--GGTMRGSSGIISSPSFP 258
Score = 39.3 bits (90), Expect = 0.019
Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 859 GATIHFSCAPGYVLKGQASIKCVPG--HPSHWSDPPPICRAASLDGFYNSRSLDVAKAPA 916
G I +SC GY+L G + C+ + + W P PICRA G S + +P+
Sbjct: 197 GDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPS 256
Score = 37.7 bits (86), Expect = 0.054
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 8/105 (7%)
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
+SC +PG + ++ +F VG ++Y C G++L G LTC + W P
Sbjct: 176 SSCGNPG--VPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVP 233
Query: 829 KCLLEQLKPCHGLSAPENGARS----PEKQLHPAGATIHFSCAPG 869
C E C G +G S P + + A T PG
Sbjct: 234 ICRAED--ACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPG 276
Score = 33.5 bits (75), Expect = 1.0
Identities = 50/237 (21%), Positives = 85/237 (35%), Gaps = 63/237 (26%)
Query: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPVCI 413
++C P + + G + T+ G S + C+ GY+L LTC+ N T W + P C+
Sbjct: 3231 VTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGT---WSGEVPQCL 3287
Query: 414 AA-CGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
CG PG P EG+ ++ +VS + + ++
Sbjct: 3288 PKFCG------------DPGIPAQGKR-----------EGKSF-IYQSEVSFSCNFPFIL 3323
Query: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
+ + + +G S +E + S C
Sbjct: 3324 VGSSTRI-------------CQADGTWSGSSPHCIEPTQTS------------------C 3352
Query: 533 YEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC 589
P V ++T + VG+ V+F C G+ L QGS C+ D W+ +P C
Sbjct: 3353 ENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLL-QGSTTRTCLP--DLTWSGIQPEC 3406
>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
precursor [Homo sapiens]
Length = 728
Score = 106 bits (264), Expect = 1e-22
Identities = 123/470 (26%), Positives = 190/470 (40%), Gaps = 56/470 (11%)
Query: 422 NATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAE----DDDRLIIRNGD 477
N G+I SPG+P +Y ++ W + P+G R+ L+F +L + D + + D
Sbjct: 25 NNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETED 84
Query: 478 NVEAPPV-YDSYEVEYLP-IEGLLSSGKHFFVELSTDSSGAA--AGMALRYEAFQQGHCY 533
V A ++ + E P E +LS G + +D S G Y A C
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 534 EPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC 593
E + + Y G SC GY L N T CR C
Sbjct: 145 EREDEELSCDHYCHNYIGG--YYCSCRFGYILHTD--------------NRT---CRVEC 185
Query: 594 SGEI-TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML---DIRVLRIGPGDVLTFY 649
S + T GV+ SP++P PY + +C++ + +EE + L DI + P +V Y
Sbjct: 186 SDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP-EVPCPY 244
Query: 650 DGDDLTA--RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
D + +VLG + G ++ + T V I F SD G++ +
Sbjct: 245 DYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY------RAAG 298
Query: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLM------CQWDLTWSED 761
+ CPEL +G PSQ + V C GY+V+ +V M C D TWS
Sbjct: 299 NECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 358
Query: 762 LPSCQRVTSCHDPGDVEHSRRLISSPK--FPVGATVQYICDQGFVLM---GSSILTCHDR 816
+P+C ++ C PG++EH S+ + ++Y C + + M + I TC +
Sbjct: 359 IPTC-KIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQ 417
Query: 817 QAGSPKWSDRA-PKCLLEQLKPCHGLSAPEN---GARSPEKQLHPAGATI 862
K R+ P CL E +P L + G R+ E L P A I
Sbjct: 418 GVWMNKVLGRSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALI 467
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/199 (27%), Positives = 76/199 (38%), Gaps = 32/199 (16%)
Query: 412 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
C C + TG I SP FP Y + C + +E EG ++L FE + E
Sbjct: 181 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIE----- 235
Query: 472 IIRNGDNVEAPPVYDSYEVEYLP-----------IEGLLSSGKHFFVELSTDSSGAAAGM 520
D+ E P YD +++ P E + + + +D+SG G
Sbjct: 236 -----DHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGW 290
Query: 521 ALRYEAFQQGHCYE--PFVKYGNFSSSTPTYPVGTTVEFSCDPGY-----TLEQGSIIIE 573
L Y A C E P V +G S Y V SCD GY +E + IE
Sbjct: 291 RLSYRA-AGNECPELQPPV-HGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIE 348
Query: 574 CVDPHDPQWNETEPACRAV 592
C+ D W+ P C+ V
Sbjct: 349 CL--KDGTWSNKIPTCKIV 365
>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
precursor [Homo sapiens]
Length = 686
Score = 102 bits (254), Expect = 2e-21
Identities = 119/451 (26%), Positives = 177/451 (39%), Gaps = 61/451 (13%)
Query: 426 GRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNVEA 481
GR+ SPGFPG Y+N+ W L AP G RL L+F L D + + +G V A
Sbjct: 28 GRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLA 87
Query: 482 PPV-YDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYG 540
+S + E P GK F L G++ + R + + +PF +
Sbjct: 88 TLCGQESTDTERAP-------GKDTFYSL-----GSSLDITFRSDYSNE----KPFTGFE 131
Query: 541 NF--SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEI- 597
F + V +CD G C + N+ C A+CSG++
Sbjct: 132 AFYAAEDIDECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKR--TCSALCSGQVF 189
Query: 598 TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTF------YDG 651
T +G + SP +P PY + C + + +EE ++LD + DV T YD
Sbjct: 190 TQRSGELSSPEYPRPYPKLSSCTYSISLEEGFSVILDF----VESFDVETHPETLCPYDF 245
Query: 652 DDLTA--RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDT 709
+ G + G ++ T VTI F +D G G+ IH+ +
Sbjct: 246 LKIQTDREEHGPFCGKTLPHRIETKSNTVTITFVTDES----GDHTGWKIHYTSTAQ--P 299
Query: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQV------VGSSVLMCQWDLTWSEDLP 763
CP PNG SP Q + + + C GY++ + S +CQ D +W +P
Sbjct: 300 CPYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMP 359
Query: 764 SCQRVTSCHDPGDVEHSR-RLISSPKFPV-GATVQYICDQGFVLM--GSSILTCH-DRQA 818
+C + C P D+ R I+ P A +QY C++ F M C D
Sbjct: 360 ACS-IVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETFYTMKVNDGKYVCEADGFW 418
Query: 819 GSPKWSDRAPKCLLEQLKPCHGLSAPENGAR 849
S K P C +P GLSA G R
Sbjct: 419 TSSKGEKSLPVC-----EPVCGLSARTTGGR 444
>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
precursor [Homo sapiens]
Length = 699
Score = 101 bits (252), Expect = 3e-21
Identities = 113/436 (25%), Positives = 177/436 (40%), Gaps = 53/436 (12%)
Query: 422 NATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAE----DDDRLIIRNGD 477
N G+I SPG+P +Y ++ W + P+G R+ L+F +L + D + + D
Sbjct: 25 NNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETED 84
Query: 478 NVEAPPV-YDSYEVEYLP-IEGLLSSGKHFFVELSTDSSGAA--AGMALRYEAFQQGHCY 533
V A ++ + E P E +LS G + +D S G Y A C
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 534 EPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC 593
E + + Y G SC GY L N T CR C
Sbjct: 145 EREDEELSCDHYCHNYIGG--YYCSCRFGYILHTD--------------NRT---CRVEC 185
Query: 594 SGEI-TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML---DIRVLRIGPGDVLTFY 649
S + T GV+ SP++P PY + +C++ + +EE + L DI + P +V Y
Sbjct: 186 SDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP-EVPCPY 244
Query: 650 DGDDLTA--RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
D + +VLG + G ++ + T V I F SD G++ +
Sbjct: 245 DYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSY------RAAG 298
Query: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLM------CQWDLTWSED 761
+ CPEL +G PSQ + V C GY+V+ +V M C D TWS
Sbjct: 299 NECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 358
Query: 762 LPSCQRVTSCHDPGDVEHSRRLISSPK--FPVGATVQYICDQGFVLM---GSSILTCHDR 816
+P+C ++ C PG++EH S+ + ++Y C + + M + I TC +
Sbjct: 359 IPTC-KIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQ 417
Query: 817 QAGSPKWSDRA-PKCL 831
K R+ P CL
Sbjct: 418 GVWMNKVLGRSLPTCL 433
Score = 56.2 bits (134), Expect = 1e-07
Identities = 54/199 (27%), Positives = 76/199 (38%), Gaps = 32/199 (16%)
Query: 412 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
C C + TG I SP FP Y + C + +E EG ++L FE + E
Sbjct: 181 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIE----- 235
Query: 472 IIRNGDNVEAPPVYDSYEVEYLP-----------IEGLLSSGKHFFVELSTDSSGAAAGM 520
D+ E P YD +++ P E + + + +D+SG G
Sbjct: 236 -----DHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGW 290
Query: 521 ALRYEAFQQGHCYE--PFVKYGNFSSSTPTYPVGTTVEFSCDPGY-----TLEQGSIIIE 573
L Y A C E P V +G S Y V SCD GY +E + IE
Sbjct: 291 RLSYRA-AGNECPELQPPV-HGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIE 348
Query: 574 CVDPHDPQWNETEPACRAV 592
C+ D W+ P C+ V
Sbjct: 349 CL--KDGTWSNKIPTCKIV 365
>gi|54792123 complement component (3d/Epstein Barr virus) receptor 2
isoform 1 [Homo sapiens]
Length = 1092
Score = 100 bits (249), Expect = 7e-21
Identities = 94/399 (23%), Positives = 161/399 (40%), Gaps = 64/399 (16%)
Query: 535 PFVKYGNFSSSTPTYPV-GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC 593
P + +G + + V G TV+++CDPGY L G+ I C+ + W+ + P C C
Sbjct: 665 PGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLV-GNKSIHCMPSGN--WSPSAPRCEETC 721
Query: 594 -----------SGEITDSAGVVLSPNWP---EPYGRGQDCIWGVHVEEDKRIMLDIRVLR 639
+G + + Y QD G+ K+I L +V+
Sbjct: 722 QHVRQSLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWF---KKIPL-CKVIH 777
Query: 640 IGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQ---- 695
P V+ V G+++G + L+ + + ++ D G +LG ++
Sbjct: 778 CHPPPVI-----------VNGKHTGMMAENFLYGN----EVSYECDQGFYLLGEKKLQCR 822
Query: 696 ----------GFVIHFFEVPRNDTCPELPEIPNGWK-SPSQPELVHGTVVTYQCYPGYQV 744
G P CP PE+ +G+K + + H +V C PG+ +
Sbjct: 823 SDSKGHGSWSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIM 881
Query: 745 VGSSVLMCQWDLTWSEDLPSC--QRVTSCHDPGDVEHSRRLISS-PKFPVGATVQYICDQ 801
GS V+ C D TW +P+C + C P + + +F G ++ Y CDQ
Sbjct: 882 NGSRVIRCHTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQ 941
Query: 802 GFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGAT 861
G++L+G ++L C WS AP C + + G ++++ GA
Sbjct: 942 GYLLVGEALLLC----THEGTWSQPAPHCKEVNCSSPADMDGIQKGLE--PRKMYQYGAV 995
Query: 862 IHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASL 900
+ C GY+L+G +C H W+ P +CR+ SL
Sbjct: 996 VTLECEDGYMLEGSPQSQCQSDH--QWNPPLAVCRSRSL 1032
Score = 92.0 bits (227), Expect = 2e-18
Identities = 101/383 (26%), Positives = 157/383 (40%), Gaps = 78/383 (20%)
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACR-AVCSGE----ITDSAGVVLS 606
GT++++SC+PGY L G I+C + W P C+ A C +T +
Sbjct: 432 GTSIKYSCNPGYVLV-GEESIQCTS--EGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR 488
Query: 607 PNWPEPYGRGQDCIWGVHVEEDKRI--MLDIRVLR---IGPGDVLTFYDG-------DDL 654
P+ G G V+ E I ++IR+ + P V+ Y+G +D
Sbjct: 489 PDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVI--YNGAHTGSSLEDF 546
Query: 655 TARVLGQYS---GPRSHFKLFTSMADVTIQFQSDP---GT----------SVLGYQQGFV 698
Y+ GP + F+ + + TI+ S+ GT S+L Q V
Sbjct: 547 PYGTTVTYTCNPGPERGVE-FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV 605
Query: 699 IHFFEVPRNDTCPELPEIPNGWK-SPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLT 757
I NG+K S + + VT++CY G+ + GSS + C+ D T
Sbjct: 606 ----------------HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNT 649
Query: 758 WSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPV-GATVQYICDQGFVLMGSSILTCHDR 816
W ++P C++ C P + H R + F V G TV Y CD G++L+G+ + C
Sbjct: 650 WDPEIPVCEK--GCQSPPGLHHGRHTGGNTVFFVSGMTVDYTCDPGYLLVGNKSIHC--- 704
Query: 817 QAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHF---SCAPGYVLK 873
S WS AP+C + C + R ++L PAG+ + SC GY L
Sbjct: 705 -MPSGNWSPSAPRC----EETCQHV-------RQSLQEL-PAGSRVELVNTSCQDGYQLT 751
Query: 874 GQASIKCVPGHPSHWSDPPPICR 896
G A C W P+C+
Sbjct: 752 GHAYQMCQDAENGIWFKKIPLCK 774
Score = 89.7 bits (221), Expect = 1e-17
Identities = 144/578 (24%), Positives = 215/578 (37%), Gaps = 82/578 (14%)
Query: 370 VTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIV 429
V S+ PG S + C +GY L G + + CL++ + W + P C A + G++
Sbjct: 170 VGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVK 227
Query: 430 SPG-FPGNYSNNLTCH--WLLEAPEGQRL-----HLHFEKVSLAED----------DDRL 471
P + N C + L+ P R + + K+ + E+ + R
Sbjct: 228 EPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRH 287
Query: 472 IIRNGDNVEAPPVYDSYEVEYLPIEG---LLSSGKHFFVELSTDSSGAAAGMALRYEAFQ 528
I + NV + +Y + P EG +L + + +G +G A R E
Sbjct: 288 IGNSLANVSYGSIV-TYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELST 346
Query: 529 QG-HCYEPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETE 586
C P + G S Y TV F+C G+TL +GS I C W +
Sbjct: 347 SAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTL-KGSKQIRC--NAQGTWEPSA 403
Query: 587 PACRAVC-------SGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLR 639
P C C +G+ D V P Y C G + ++ I +
Sbjct: 404 PVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKY----SCNPGYVLVGEESIQCTSEGVW 459
Query: 640 IGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQ--QGF 697
P + T R L + P+ F DV S YQ QG
Sbjct: 460 TPPVPQCK-VAACEATGRQL--LTKPQHQF----VRPDVNSSCGEGYKLSGSVYQECQGT 512
Query: 698 VIHFFEVP--RNDTCPELPEIPNGWKSPSQPE-LVHGTVVTYQCYPG------YQVVGSS 748
+ F E+ + TCP P I NG + S E +GT VTY C PG + ++G S
Sbjct: 513 IPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGES 572
Query: 749 VLMC----QWDLTWSEDLPSCQ------RVTSCHDPGDVEHSRRLISSPKFPVGATVQYI 798
+ C Q TWS P C+ + + H + S + +P F TV +
Sbjct: 573 TIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGK--EAPYF-YNDTVTFK 629
Query: 799 CDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQL-HP 857
C GF L GSS + C W P C K C +G + +
Sbjct: 630 CYSGFTLKGSSQIRC----KADNTWDPEIPVC----EKGCQSPPGLHHGRHTGGNTVFFV 681
Query: 858 AGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
+G T+ ++C PGY+L G SI C+P +WS P C
Sbjct: 682 SGMTVDYTCDPGYLLVGNKSIHCMPS--GNWSPSAPRC 717
Score = 77.8 bits (190), Expect = 5e-14
Identities = 60/211 (28%), Positives = 93/211 (44%), Gaps = 19/211 (9%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPS 764
+C P I NG S + GTV+ Y C ++++G L+C + D TW + P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 765 CQ---RVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSP 821
C+ + +SC +P V ++ S + G +V + C F + G+ + C QA +
Sbjct: 82 CEYFNKYSSCPEP-IVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC---QANNM 137
Query: 822 KWSDRAPKCLLEQLKPCHGLSAPENGARSPEK--QLHPAGATIHFSCAPGYVLKGQASIK 879
R P C+ C L NG + E + P G ++ +SC GY+L G+ I
Sbjct: 138 WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP-GLSVTYSCESGYLLVGEKIIN 196
Query: 880 CVPGHPSHWSDPPPIC---RAASLDGFYNSR 907
C+ WS PP C R SL F N +
Sbjct: 197 CLSS--GKWSAVPPTCEEARCKSLGRFPNGK 225
Score = 77.8 bits (190), Expect = 5e-14
Identities = 58/191 (30%), Positives = 85/191 (44%), Gaps = 18/191 (9%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSED-LPSCQR 767
+CPE P +P G+K HG VT+ C + + G+ + CQ + W LP+C
Sbjct: 90 SCPE-PIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVS 148
Query: 768 VTSCHDPG-----DVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPK 822
V P + H+ + S G +V Y C+ G++L+G I+ C S K
Sbjct: 149 VFPLECPALPMIHNGHHTSENVGS--IAPGLSVTYSCESGYLLVGEKIINC----LSSGK 202
Query: 823 WSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCV- 881
WS P C E+ + C L NG + E + G T +F C GY L+G S +CV
Sbjct: 203 WSAVPPTC--EEAR-CKSLGRFPNG-KVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258
Query: 882 PGHPSHWSDPP 892
G W+ P
Sbjct: 259 AGQGVAWTKMP 269
Score = 73.2 bits (178), Expect = 1e-12
Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 34/207 (16%)
Query: 710 CPELPEIPNGWKSPSQP-ELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
C P I NG K GT + Y C PGY +VG + C + W+ +P C +V
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC-KV 468
Query: 769 TSCHDPGDVEHSRRLISSPKFP-VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA 827
+C G R+L++ P+ V V C +G+ L GS C G+ W
Sbjct: 469 AACEATG-----RQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ----GTIPW---- 515
Query: 828 PKCLLEQLKPCHGLSAPE-----NGARSPEK-QLHPAGATIHFSCAPG------YVLKGQ 875
+++ C ++ P NGA + + P G T+ ++C PG + L G+
Sbjct: 516 ----FMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGE 571
Query: 876 ASIKCVPGHPSH--WSDPPPICRAASL 900
++I+C WS P P+C+ + L
Sbjct: 572 STIRCTSNDQERGTWSGPAPLCKLSLL 598
Score = 64.3 bits (155), Expect = 5e-10
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 7/130 (5%)
Query: 710 CPELPEIPNGWKSPSQ-PELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
CP P+ PNG + G + Y C GY +VG ++L+C + TWS+ P C+ V
Sbjct: 910 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 969
Query: 769 TSCHDPGDVEHSRRLISSPK-FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA 827
+C P D++ ++ + K + GA V C+ G++L GS C +W+
Sbjct: 970 -NCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ----SDHQWNPPL 1024
Query: 828 PKCLLEQLKP 837
C L P
Sbjct: 1025 AVCRSRSLAP 1034
Score = 63.5 bits (153), Expect = 9e-10
Identities = 53/200 (26%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 710 CPELPEIPNGWK-SPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
CP LP I NG S + + G VTY C GY +VG ++ C WS P+C+
Sbjct: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEE- 212
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
C G + ++ P VG T + CD+G+ L G C G W+ + P
Sbjct: 213 ARCKSLGRFPNG-KVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWT-KMP 269
Query: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPA-GATIHFSCAP------GYVLKGQASIKCV 881
C E++ C NG + + G+ + ++C P ++L G+++++C
Sbjct: 270 VC--EEIF-CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCT 326
Query: 882 --PGHPSHWSDPPPICRAAS 899
WS P P C ++
Sbjct: 327 VDSQKTGTWSGPAPRCELST 346
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 99.4 bits (246), Expect = 2e-20
Identities = 157/669 (23%), Positives = 245/669 (36%), Gaps = 173/669 (25%)
Query: 337 LPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLT 396
+PP G G A + C P P G + G F C GYQL G +T
Sbjct: 1773 VPPYTGDGK----NCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKIT 1828
Query: 397 CLNATQPFWDSKEPVCIA-ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRL 455
CL + + W+ P C A +CG P P N C L G ++
Sbjct: 1829 CLESGE--WNHLIPYCKAVSCG------------KPAIPEN-----GCIEELAFTFGSKV 1869
Query: 456 HLHFEK-VSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFF---VELST 511
K +LA D + + N +PPV + + +++GK+ LST
Sbjct: 1870 TYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSS---PENINNGKYILSGLTYLST 1926
Query: 512 DSSGAAAGMALR----YEAFQQG------------HCYEP-FVKYGNFSSSTPTYPVGTT 554
S G +L+ E G C EP +K + + T+ T
Sbjct: 1927 ASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFR--NT 1984
Query: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGE--ITDSAGVVLSPNWPEP 612
V ++C GYTL G IEC+ D +W+ ++ C AV E I D A PE
Sbjct: 1985 VTYTCKEGYTLA-GLDTIECLA--DGKWSRSDQQCLAVSCDEPPIVDHAS-------PET 2034
Query: 613 YGR------GQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPR 666
R C G + ++ +++ + + + P +G D+ + P
Sbjct: 2035 AHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPP-------EGQDMPRCIAHFCEKPP 2087
Query: 667 S-HFKLFTSMADVTIQFQSDPGTSVLGYQ--QGFVIHF---FEVPRNDT----------- 709
S + + S++ SV+ ++ +GFV++ E R
Sbjct: 2088 SVSYSILESVSKAKFA-----AGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCI 2142
Query: 710 ---CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQ 766
C E P I NG+ S S G +V Y C G+ + G C+ WS +P+C
Sbjct: 2143 PVRCGEPPSIMNGYASGSNYSF--GAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCH 2200
Query: 767 RVTSCHDP-----GDVEHSR----------------RLISSPKF---------------- 789
V SC +P G +EH+ + + SP F
Sbjct: 2201 PV-SCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMC 2259
Query: 790 ---------------------PVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA- 827
VG+ VQ+ C++G+ L+G S TC S KW+ ++
Sbjct: 2260 VPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQK----SGKWNKKSN 2315
Query: 828 PKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
PKC+ P P + K+L + FSC G+VL+G + +KC+P
Sbjct: 2316 PKCM-----PAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPS--QQ 2368
Query: 888 WSDPPPICR 896
W+D P+C+
Sbjct: 2369 WNDSFPVCK 2377
Score = 94.4 bits (233), Expect = 5e-19
Identities = 154/654 (23%), Positives = 238/654 (36%), Gaps = 137/654 (20%)
Query: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIA 414
+ C P+ G + T LH G + + C G++L+G LTCL WD P C A
Sbjct: 2496 IECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGD--WDVDAPSCNA 2553
Query: 415 A-C-------GGVIRNA--TTGRIVS----PGFPGNYSNNLTCH---WLLEAPE------ 451
C G + A + G I+ PGF TC W P
Sbjct: 2554 IHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPIDC 2613
Query: 452 GQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLP--IEGLLSSGKHFFVEL 509
G H+ F + +DD + D +E P Y + P + + + ++
Sbjct: 2614 GLPPHIDFGDCTKLKDDQGYFEQEDDMMEVP-----YVTPHPPYHLGAVAKTWENTKESP 2668
Query: 510 STDSSGAAAGMALRYEAFQQGH---------CYEPFVKYGNFSS------STPTYP---- 550
+T SS G + Y G+ C E G+ S PT P
Sbjct: 2669 ATHSSNFLYGTMVSYTC-NPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGF 2727
Query: 551 -------VGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA--------VCSG 595
+G+ V++SC PG+ L GS + C++ + +W+ P C A V +G
Sbjct: 2728 LRFTETSMGSAVQYSCKPGHILA-GSDLRLCLE--NRKWSGASPRCEAISCKKPNPVMNG 2784
Query: 596 EITDSAGVVLS-------PNWPEPYGRGQDCIWGVHVEEDKRIMLDIR-----VLRIGP- 642
I S LS P + + C + +ED+ I + + V G
Sbjct: 2785 SIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQV 2844
Query: 643 -GDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMAD------VTIQFQSDPG-----TSV 690
GD TF + T G RS L V ++ + P T
Sbjct: 2845 RGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEG 2904
Query: 691 LGY----------QQGFVIHFF-------------EVP--RNDTCPELPEIPNGWKSPSQ 725
L Y +G+++H E+P + C ++ +G+ P+
Sbjct: 2905 LDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGF--PNG 2962
Query: 726 PELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLIS 785
+HG + YQC+PGY++ G+S C + +WS PSC C P +E+ ++
Sbjct: 2963 FSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSC-LPCRCSTP-VIEYG--TVN 3018
Query: 786 SPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPE 845
F G + C +GF L+G S +TC +WS P C + C L
Sbjct: 3019 GTDFDCGKAARIQCFKGFKLLGLSEITCE----ADGQWSSGFPHC---EHTSCGSLPMIP 3071
Query: 846 NGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
N S I +SC GYV++G + + C WS P P+C S
Sbjct: 3072 NAFISETSSWKE--NVITYSCRSGYVIQGSSDLICT--EKGVWSQPYPVCEPLS 3121
Score = 83.2 bits (204), Expect = 1e-15
Identities = 66/229 (28%), Positives = 96/229 (41%), Gaps = 52/229 (22%)
Query: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
CP L ++ S+ +L G+ V C PG+Q+VG+ V C W++ LP C+R+
Sbjct: 1631 CPRLGGSVPHLRTASE-DLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERI- 1688
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
SC P +E+ S+ F G+TV Y C+ G+ L+G S + C D + W+ +P
Sbjct: 1689 SCGVPPPLENG--FHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTD----NGSWNGVSPS 1742
Query: 830 CL---------------------------------------LEQLKPCHGLSAPENGARS 850
CL E +K C PENG S
Sbjct: 1743 CLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIK-CKAPGNPENGHSS 1801
Query: 851 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAAS 899
E ++ GA + FSC GY L G I C+ W+ P C+A S
Sbjct: 1802 GE--IYTVGAEVTFSCQEGYQLMGVTKITCL--ESGEWNHLIPYCKAVS 1846
Score = 79.0 bits (193), Expect = 2e-14
Identities = 58/186 (31%), Positives = 83/186 (44%), Gaps = 17/186 (9%)
Query: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
CP+ EIPNG L + + Y C PG+++VG++ +C + W P+C+ +
Sbjct: 2440 CPQPEEIPNGIIDVQG--LAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI- 2496
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
C P ++ + + S G TV Y C++GF L G S LTC + + W AP
Sbjct: 2497 ECLKPKEILNGK--FSYTDLHYGQTVTYSCNRGFRLEGPSALTCLE----TGDWDVDAPS 2550
Query: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWS 889
C C ENG E + GA I +SC PG+ + G A C S WS
Sbjct: 2551 C---NAIHCDSPQPIENGF--VEGADYSYGAIIIYSCFPGFQVAGHAMQTC---EESGWS 2602
Query: 890 DPPPIC 895
P C
Sbjct: 2603 SSIPTC 2608
Score = 77.4 bits (189), Expect = 6e-14
Identities = 61/225 (27%), Positives = 90/225 (40%), Gaps = 51/225 (22%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
+C P + NG+ S + G+ VTYQC GY ++G S + C + +W+ PSC V
Sbjct: 1689 SCGVPPPLENGFHSAD--DFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDV 1746
Query: 769 TSCHDPGDV-EHSRRL-------------------------------------ISSPKFP 790
C D EH+ L S +
Sbjct: 1747 DECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYT 1806
Query: 791 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARS 850
VGA V + C +G+ LMG + +TC + S +W+ P C + C + PENG
Sbjct: 1807 VGAEVTFSCQEGYQLMGVTKITCLE----SGEWNHLIPYC---KAVSCGKPAIPENGC-- 1857
Query: 851 PEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPIC 895
E+ G+ + + C GY L G C+ S WS PP+C
Sbjct: 1858 IEELAFTFGSKVTYRCNKGYTLAGDKESSCLAN--SSWSHSPPVC 1900
Score = 74.3 bits (181), Expect = 5e-13
Identities = 90/376 (23%), Positives = 139/376 (36%), Gaps = 74/376 (19%)
Query: 545 STPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV--------CSGE 596
S + G+TV + C+ GY L G + C D + WN P+C V CS
Sbjct: 1702 SADDFYAGSTVTYQCNNGYYL-LGDSRMFCTD--NGSWNGVSPSCLDVDECAVGSDCSEH 1758
Query: 597 IT--DSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDL 654
+ + G + P G G++C + +
Sbjct: 1759 ASCLNVDGSYICSCVPPYTGDGKNC-------------------------------AEPI 1787
Query: 655 TARVLGQYSGPRSHFKLFTSMADVTIQ----FQSDPGTSVLGYQQGFVIHFFEVPRNDTC 710
+ G S +++T A+VT +Q T + + G H + +C
Sbjct: 1788 KCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSC 1847
Query: 711 --PELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
P +PE NG + G+ VTY+C GY + G C + +WS P C+ V
Sbjct: 1848 GKPAIPE--NG--CIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPV 1903
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
C P ++ + + ++S + +T Y CD G+ L G SI+ C S W DRAP
Sbjct: 1904 -KCSSPENINNGKYILSGLTYL--STASYSCDTGYSLQGPSIIEC----TASGIW-DRAP 1955
Query: 829 KCLLEQLKPCHGLSAPENGARSP---EKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHP 885
CH + E A T+ ++C GY L G +I+C+
Sbjct: 1956 PA-------CHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLA--D 2006
Query: 886 SHWSDPPPICRAASLD 901
WS C A S D
Sbjct: 2007 GKWSRSDQQCLAVSCD 2022
Score = 74.3 bits (181), Expect = 5e-13
Identities = 134/594 (22%), Positives = 204/594 (34%), Gaps = 108/594 (18%)
Query: 376 GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI-AACG-------GVIRNATTGR 427
G + C G+ +KG + TC Q W S P C +CG G + + TTGR
Sbjct: 2165 GAMVAYSCNKGFYIKGEKKSTCEATGQ--WSSPIPTCHPVSCGEPPKVENGFLEH-TTGR 2221
Query: 428 IV--------SPGFPGNYSNNLTC----HWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRN 475
I +PG+ S C HW E+P + L K ++
Sbjct: 2222 IFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPL-MCVPLDCGKPPPIQNG----FMK 2276
Query: 476 GDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ----GH 531
G+N E +V++ EG EL DSS +
Sbjct: 2277 GENFEV-----GSKVQFFCNEGY---------ELVGDSSWTCQKSGKWNKKSNPKCMPAK 2322
Query: 532 CYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
C EP + T VG V FSC G+ L QG +++C+ QWN++ P C+
Sbjct: 2323 CPEPPLLENQLVLKELTTEVGV-VTFSCKEGHVL-QGPSVLKCLPSQ--QWNDSFPVCKI 2378
Query: 592 V-CSGEITDSAGVVLSPNWPEPYGR--GQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTF 648
V C+ S GV + P+ +G C+ G + + + P
Sbjct: 2379 VLCTPPPLISFGVPI-PSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVP 2437
Query: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRND 708
+ + + L T++ F+ T+ L + G + +
Sbjct: 2438 VECPQ-PEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAI 2496
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
C + EI NG S +L +G VTY C G+++ G S L C W D PSC +
Sbjct: 2497 ECLKPKEILNG--KFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAI 2554
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
C P +E+ + + GA + Y C GF + G ++ TC + WS P
Sbjct: 2555 -HCDSPQPIENG--FVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEE-----SGWSSSIP 2606
Query: 829 KCL--------------LEQLKPCHGLSAPENGARS-PEKQLHPA--------------- 858
C+ +LK G E+ P HP
Sbjct: 2607 TCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKE 2666
Query: 859 -----------GATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLD 901
G + ++C PGY L G + C W+ P C + D
Sbjct: 2667 SPATHSSNFLYGTMVSYTCNPGYELLGNPVLIC--QEDGTWNGSAPSCISIECD 2718
Score = 70.5 bits (171), Expect = 8e-12
Identities = 85/377 (22%), Positives = 137/377 (36%), Gaps = 62/377 (16%)
Query: 549 YPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV-CSGEITDSAGVVLSP 607
+ G+ V + C+ GYTL G C+ + W+ + P C V CS
Sbjct: 1863 FTFGSKVTYRCNKGYTLA-GDKESSCLA--NSSWSHSPPVCEPVKCSS------------ 1907
Query: 608 NWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRS 667
PE G+ + G+ D GP + + TA + + P
Sbjct: 1908 --PENINNGKYILSGLTYLSTASYSCDTGYSLQGPSII-------ECTASGIWDRAPPAC 1958
Query: 668 HFKLFTSMADV--------------TIQFQSDPGTSVLGYQQGFVIHFFEVPRND----- 708
H + T+ + G ++ G + + R+D
Sbjct: 1959 HLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLA 2018
Query: 709 -TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTW----SEDLP 763
+C E P + + SP + G + Y C GY + +S L+C W +D+P
Sbjct: 2019 VSCDEPPIVDHA--SPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMP 2076
Query: 764 SCQRVTSCHDPGDVEHS-RRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPK 822
C C P V +S +S KF G+ V + C +GFVL S+ + C + G
Sbjct: 2077 RC-IAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIEC--MRGGQWN 2133
Query: 823 WSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVP 882
S + +C+ + C + NG S + GA + +SC G+ +KG+ C
Sbjct: 2134 PSPMSIQCIPVR---CGEPPSIMNGYASGSN--YSFGAMVAYSCNKGFYIKGEKKSTCEA 2188
Query: 883 GHPSHWSDPPPICRAAS 899
WS P P C S
Sbjct: 2189 --TGQWSSPIPTCHPVS 2203
Score = 70.5 bits (171), Expect = 8e-12
Identities = 53/170 (31%), Positives = 77/170 (45%), Gaps = 20/170 (11%)
Query: 731 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
G V Y C GY + G S C + TWS +P C + C P + + L+S +F
Sbjct: 3318 GPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLC-KPNPCPVPFVIPENA-LLSEKEFY 3375
Query: 791 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLK---PCHGLSAPENG 847
V V C +GF+L G I+TC+ + W+ + KC E++ P H +A G
Sbjct: 3376 VDQNVSIKCREGFLLQGHGIITCNPDET----WTQTSAKC--EKISCGPPAHVENAIARG 3429
Query: 848 ARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRA 897
+ G I +SC GY+L+G C+ W+ PPICRA
Sbjct: 3430 VH------YQYGDMITYSCYSGYMLEGFLRSVCLEN--GTWTS-PPICRA 3470
Score = 69.3 bits (168), Expect = 2e-11
Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 11/168 (6%)
Query: 710 CPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVT 769
CP L NG+ + +C+PG+ +VGSS+++C + WS C RV
Sbjct: 378 CPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYC-RVR 436
Query: 770 SCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
+C +H S+ + T CD+G+ L GS LTC G+ +W P+
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQ----GNSQWDGPEPR 492
Query: 830 CLLEQLKPCHGLSAPENGARSPE---KQLHPAGATIHFSCAPGYVLKG 874
C+ + C P++ SP KQ G + SC G++L G
Sbjct: 493 CV---ERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSG 537
Score = 62.8 bits (151), Expect = 2e-09
Identities = 54/188 (28%), Positives = 78/188 (41%), Gaps = 27/188 (14%)
Query: 723 PSQPELVHGTVV----------TYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCH 772
P PE HG VV YQC PGY++ G+ +CQ + WS + C+ T C
Sbjct: 3244 PESPE--HGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKE-TRCE 3300
Query: 773 DPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLL 832
P + + + I + G V Y C++G+ L G S C + + WS P C
Sbjct: 3301 TPLEFLNGKADIENR--TTGPNVVYSCNRGYSLEGPSEAHCTE----NGTWSHPVPLC-- 3352
Query: 833 EQLKPCH-GLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDP 891
+ PC PEN S EK+ + + C G++L+G I C P W+
Sbjct: 3353 -KPNPCPVPFVIPENALLS-EKEFY-VDQNVSIKCREGFLLQGHGIITCNPDET--WTQT 3407
Query: 892 PPICRAAS 899
C S
Sbjct: 3408 SAKCEKIS 3415
Score = 62.4 bits (150), Expect = 2e-09
Identities = 50/177 (28%), Positives = 72/177 (40%), Gaps = 22/177 (12%)
Query: 728 LVHGT------VVTYQCYPGYQVVGSSVLMCQWDLTWSEDL--PSCQRVTSCHDPGDVEH 779
LVHG V+ C GY G ++ +CQ D TW SC V SC P EH
Sbjct: 3191 LVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPV-SCGKPESPEH 3249
Query: 780 SRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCH 839
+ K+ +T+ Y C+ G+ L G+ C + + +WS C + C
Sbjct: 3250 G--FVVGSKYTFESTIIYQCEPGYELEGNRERVCQENR----QWSGGVAIC---KETRCE 3300
Query: 840 GLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICR 896
NG E + G + +SC GY L+G + C WS P P+C+
Sbjct: 3301 TPLEFLNGKADIENR--TTGPNVVYSCNRGYSLEGPSEAHCTEN--GTWSHPVPLCK 3353
Score = 58.9 bits (141), Expect = 2e-08
Identities = 132/669 (19%), Positives = 207/669 (30%), Gaps = 215/669 (32%)
Query: 355 LSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIA 414
+ C P P G + T G + ++ C G+ L G+ CL + W P C A
Sbjct: 2715 IECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRK--WSGASPRCEA 2772
Query: 415 --------ACGGVIRNATTGRIVS------PGFPGNYSNNLTCHWLLEAPEGQRLHLHFE 460
G I+ + + + PG+ N + TC + + E
Sbjct: 2773 ISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTC-------QDDKNWDEDE 2825
Query: 461 KVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDS------- 513
+ + D + V E+EY EG L G V L+ S
Sbjct: 2826 PICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPD 2885
Query: 514 -------------SGAAAGMALRYEAFQQGHCYEPFVKYG----------NFSSSTPT-- 548
+G G+ + HC+E ++ +G N+ + P
Sbjct: 2886 CVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCK 2945
Query: 549 -------------YPVGTT------VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPA- 588
+P G + +++ C PGY L G+ C+ + W+ + P+
Sbjct: 2946 PVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLH-GNSSRRCLS--NGSWSGSSPSC 3002
Query: 589 --CRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVL 646
CR CS + + V G DC ++ K L +G ++
Sbjct: 3003 LPCR--CSTPVIEYGTV---------NGTDFDCGKAARIQCFKGFKL------LGLSEI- 3044
Query: 647 TFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPR 706
T GQ+S H +
Sbjct: 3045 --------TCEADGQWSSGFPHCE------------------------------------ 3060
Query: 707 NDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQ 766
+ +C LP IPN + S + + V+TY C GY + GSS L+C WS+ P C+
Sbjct: 3061 HTSCGSLPMIPNAFISETSSWKEN--VITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCE 3118
Query: 767 RVTSCHDPGDVEHS----------------------------------------RRLISS 786
+ SC P V ++ R+ S
Sbjct: 3119 PL-SCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCS 3177
Query: 787 PK-----------------FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPK 829
PK F V V C +G+ G +I C P +SD
Sbjct: 3178 PKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSD---- 3233
Query: 830 CLLEQLKP--CHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSH 887
E P C +PE+G K + +TI + C PGY L+G C
Sbjct: 3234 ---ESCSPVSCGKPESPEHGFVVGSK--YTFESTIIYQCEPGYELEGNRERVCQENR--Q 3286
Query: 888 WSDPPPICR 896
WS IC+
Sbjct: 3287 WSGGVAICK 3295
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/119 (30%), Positives = 50/119 (42%), Gaps = 7/119 (5%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSC--Q 766
TCP L + +G S S E+++ T C GY++ GS L CQ + W P C +
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVER 496
Query: 767 RVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMG-SSILTCHDRQAGSPKWS 824
++ P DV S G C QGF+L G +L C S KW+
Sbjct: 497 HCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRC----TTSGKWN 551
Score = 36.6 bits (83), Expect = 0.12
Identities = 28/99 (28%), Positives = 35/99 (35%), Gaps = 12/99 (12%)
Query: 808 SSILTCHDRQAGSPKWSDRAPKCLLEQ----------LKPCHGLSAPENGARSPEKQLHP 857
SS + C D SP S C+ + L C L PENG +
Sbjct: 338 SSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNH 397
Query: 858 AGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICR 896
A C PG+ L G + I C+P WS CR
Sbjct: 398 FNAACGVRCHPGFDLVGSSIILCLPN--GLWSGSESYCR 434
Score = 35.4 bits (80), Expect = 0.27
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 5/78 (6%)
Query: 531 HCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACR 590
H +P K+G+ S ST TT +CD GY LE GS + C + QW+ EP C
Sbjct: 440 HLRQP--KHGHISCSTREMLYKTTCLVACDEGYRLE-GSDKLTC--QGNSQWDGPEPRCV 494
Query: 591 AVCSGEITDSAGVVLSPN 608
V++SP+
Sbjct: 495 ERHCSTFQMPKDVIISPH 512
Score = 33.9 bits (76), Expect = 0.78
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 356 SCHFPRRPAYGDVTVTSLHP--GGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
+C R+P +G ++ ++ + C GY+L+G+ LTC +Q WD EP C+
Sbjct: 437 TCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQ--WDGPEPRCV 494
Score = 32.0 bits (71), Expect = 3.0
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 730 HGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
+G ++TY CY GY + G +C + TW+ P C+ V
Sbjct: 3434 YGDMITYSCYSGYMLEGFLRSVCLENGTWTSP-PICRAV 3471
>gi|86793109 complement receptor 1 isoform S precursor [Homo sapiens]
Length = 2489
Score = 97.8 bits (242), Expect = 4e-20
Identities = 141/603 (23%), Positives = 228/603 (37%), Gaps = 94/603 (15%)
Query: 357 CHFPRRPAYGDVTVT---SLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC- 412
C P +G+ T + + PG + C GY L+GA L C Q W + P C
Sbjct: 1647 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC--TPQGDWSPEAPRCA 1704
Query: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLH--------------LH 458
+ +C + GR++ FP N ++ + EG RL L
Sbjct: 1705 VKSCDDFLGQLPHGRVL---FPLNLQLGAKVSFVCD--EGFRLKGSSVSHCVLVGMRSLW 1759
Query: 459 FEKVSLAED---DDRLIIRNGDNVEAPPVYDSY--EVEYL----PIEGL---LSSGKHFF 506
V + E + I NG + P Y E+ Y P G+ L
Sbjct: 1760 NNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIR 1819
Query: 507 VELSTDSSGAAAGMALRYE-AFQQGHCYEPFVKYGNFSSSTPT-------YPVGTTVEFS 558
+G + A R E + + GHC P F ++PT +PVGT++ +
Sbjct: 1820 CTSDPHGNGVWSSPAPRCELSVRAGHCKTP----EQFPFASPTIPINDFEFPVGTSLNYE 1875
Query: 559 CDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGR--G 616
C PGY + SI C++ + W+ E CR G + ++ N +G
Sbjct: 1876 CRPGYFGKMFSI--SCLE--NLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1931
Query: 617 QDC---------------IWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQ 661
C + G +V DK+ + ++ P ++ +GD +
Sbjct: 1932 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPI-CEIISCEPPPTIS--NGDFYSNNRTSF 1988
Query: 662 YSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVP-----RNDTCPELPEI 716
++G ++ T D F+ S+ + + + P + C PE+
Sbjct: 1989 HNGTVVTYQCHTG-PDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTA-PEV 2046
Query: 717 PNGWKSPSQPELVHGT-VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPG 775
N + P T ++ ++C PG+ +VGS + CQ + W LP C RV C P
Sbjct: 2047 ENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV--CQPPP 2104
Query: 776 DVEHSRRLIS-SPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQ 834
++ H +S F G V Y C+ + L G++ L C WS AP+C ++
Sbjct: 2105 EILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHC----TPQGDWSPEAPRCTVKS 2160
Query: 835 LKPCHGLSAPENGARSP-EKQLHPAGATIHFSCAPGYVLKGQASIKCV-PGHPSHWSDPP 892
G P P QL GA + F C G+ LKG+++ CV G + W+
Sbjct: 2161 CDDFLG-QLPHGRVLLPLNLQL---GAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSV 2216
Query: 893 PIC 895
P+C
Sbjct: 2217 PVC 2219
Score = 97.1 bits (240), Expect = 7e-20
Identities = 128/571 (22%), Positives = 208/571 (36%), Gaps = 91/571 (15%)
Query: 356 SCHFPRRPAYGDV-TVTSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPVCI 413
SC P P G V + + G ++ C GY+L G+ TC+ + WD++ P+C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
G+ T G +S + ++ + G+++ FE V
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKV---FELVG---------- 209
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
P +Y + + D G +G A + C
Sbjct: 210 -------EPSIYCTS---------------------NDDQVGIWSGPAP--QCIIPNKCT 239
Query: 534 EPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
P V+ G S + + + VEF C PG+ + +G ++C + +W P+C V
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALN--KWEPELPSCSRV 296
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIG----PGDVLTF 648
C D + + + GQ+ + D R +R G
Sbjct: 297 CQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEV 355
Query: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGF-VIHFFEVPRN 707
DD +GQ R F + + + F D G + G + V+ E N
Sbjct: 356 KSCDDF----MGQLLNGRVLFPVNLQLG-AKVDFVCDEGFQLKGSSASYCVLAGMESLWN 410
Query: 708 DT--------CPELPEIPNGWKSPSQPELV-HGTVVTYQCYP------GYQVVGSSVLMC 752
+ CP P IPNG + E+ G V Y C P + ++G S + C
Sbjct: 411 SSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRC 470
Query: 753 ----QWDLTWSEDLPSCQRVTSCHDPGDVEHS--RRLISSPKFPVGATVQYICDQGFVLM 806
Q + WS P C + C P + + ++ FP+G +++Y C +
Sbjct: 471 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR 530
Query: 807 GSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSC 866
SI TC D WS C + K C P NG + G+ I++SC
Sbjct: 531 PFSI-TCLDNLV----WSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQ-VGSRINYSC 581
Query: 867 APGYVLKGQASIKCV-PGHPSHWSDPPPICR 896
G+ L G +S +C+ G+ +HWS PPIC+
Sbjct: 582 TTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Score = 94.4 bits (233), Expect = 5e-19
Identities = 128/571 (22%), Positives = 205/571 (35%), Gaps = 91/571 (15%)
Query: 356 SCHFPRRPAYGDV-TVTSLHPGGSARFHCATGYQLKGARHLTC-LNATQPFWDSKEPVCI 413
SC P P G V +T + G + C TG++L G C L+ W +K P+C
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
G+ G +S + ++ + G+++ FE V
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV---FELVG---------- 659
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
P +Y + + D G +G A + C
Sbjct: 660 -------EPSIYCTS---------------------NDDQVGIWSGPAP--QCIIPNKCT 689
Query: 534 EPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
P V+ G S + + + VEF C PG+ + +G ++C + +W P+C V
Sbjct: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALN--KWEPELPSCSRV 746
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIG----PGDVLTF 648
C D + + + GQ+ + D R +R G
Sbjct: 747 CQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEV 805
Query: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGF-VIHFFEVPRN 707
DD +GQ R F + + + F D G + G + V+ E N
Sbjct: 806 KSCDDF----MGQLLNGRVLFPVNLQLG-AKVDFVCDEGFQLKGSSASYCVLAGMESLWN 860
Query: 708 DT--------CPELPEIPNGWKSPSQPELV-HGTVVTYQCYP------GYQVVGSSVLMC 752
+ CP P IPNG + E+ G V Y C P + ++G S + C
Sbjct: 861 SSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRC 920
Query: 753 ----QWDLTWSEDLPSCQRVTSCHDPGDVEHS--RRLISSPKFPVGATVQYICDQGFVLM 806
Q + WS P C + C P + + ++ FP+G +++Y C +
Sbjct: 921 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR 980
Query: 807 GSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSC 866
SI TC D WS C + K C P NG + G+ I++SC
Sbjct: 981 PFSI-TCLDNLV----WSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQ-VGSRINYSC 1031
Query: 867 APGYVLKGQASIKCV-PGHPSHWSDPPPICR 896
G+ L G +S +C+ G+ +HWS PPIC+
Sbjct: 1032 TTGHRLIGHSSAECILSGNAAHWSTKPPICQ 1062
Score = 94.4 bits (233), Expect = 5e-19
Identities = 128/571 (22%), Positives = 205/571 (35%), Gaps = 91/571 (15%)
Query: 356 SCHFPRRPAYGDV-TVTSLHPGGSARFHCATGYQLKGARHLTC-LNATQPFWDSKEPVCI 413
SC P P G V +T + G + C TG++L G C L+ W +K P+C
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 1062
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
G+ G +S + ++ + G+++ FE V
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV---FELVG---------- 1109
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
P +Y + + D G +G A + C
Sbjct: 1110 -------EPSIYCTS---------------------NDDQVGIWSGPAP--QCIIPNKCT 1139
Query: 534 EPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
P V+ G S + + + VEF C PG+ + +G ++C + +W P+C V
Sbjct: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALN--KWEPELPSCSRV 1196
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIG----PGDVLTF 648
C D + + + GQ+ + D R +R G
Sbjct: 1197 CQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEV 1255
Query: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGF-VIHFFEVPRN 707
DD +GQ R F + + + F D G + G + V+ E N
Sbjct: 1256 KSCDDF----MGQLLNGRVLFPVNLQLG-AKVDFVCDEGFQLKGSSASYCVLAGMESLWN 1310
Query: 708 DT--------CPELPEIPNGWKSPSQPELV-HGTVVTYQCYP------GYQVVGSSVLMC 752
+ CP P IPNG + E+ G V Y C P + ++G S + C
Sbjct: 1311 SSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRC 1370
Query: 753 ----QWDLTWSEDLPSCQRVTSCHDPGDVEHS--RRLISSPKFPVGATVQYICDQGFVLM 806
Q + WS P C + C P + + ++ FP+G +++Y C +
Sbjct: 1371 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR 1430
Query: 807 GSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSC 866
SI TC D WS C + K C P NG + G+ I++SC
Sbjct: 1431 PFSI-TCLDNLV----WSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQ-VGSRINYSC 1481
Query: 867 APGYVLKGQASIKCV-PGHPSHWSDPPPICR 896
G+ L G +S +C+ G+ +HWS PPIC+
Sbjct: 1482 TTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1512
Score = 92.8 bits (229), Expect = 1e-18
Identities = 147/609 (24%), Positives = 230/609 (37%), Gaps = 131/609 (21%)
Query: 372 SLHPGGSARFHCATGYQLKGARHLTCLNA-TQPFWDSKEPVC---IAACGGVIRNAT-TG 426
+L G F C G+QLKG+ C+ A + W+S PVC VI N TG
Sbjct: 375 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTG 434
Query: 427 RIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYD 486
+ + FP + N TC G L E D + G+ V + P
Sbjct: 435 KPLEV-FPFGKTVNYTCD--PHPDRGTSFDLIGESTIRCTSDPQ-----GNGVWSSPA-- 484
Query: 487 SYEVEYLPIEGLLSSGKHFF---VELSTDSSGAAAGMALRYEAFQQGH-------CYEPF 536
I G + HF ++ T++S G +L+YE + + C +
Sbjct: 485 ----PRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 540
Query: 537 VKYG------NFSSSTPTYPV------------GTTVEFSCDPGYTLEQGSIIIECV-DP 577
V S TP PV G+ + +SC G+ L G EC+
Sbjct: 541 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLI-GHSSAECILSG 599
Query: 578 HDPQWNETEPACRAV-CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIR 636
+ W+ P C+ + C T + G +S N E + G + + R + ++
Sbjct: 600 NAAHWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGSVVTYRCNPGSGGRKVFEL- 657
Query: 637 VLRIGPGDVLTFYDGDDLTARVLGQYSGPR--------------------SHFKLFTSMA 676
+G + + D + G +SGP S + S+
Sbjct: 658 ---VGEPSIYCTSNDDQV-----GIWSGPAPQCIIPNKCTPPNVENGILVSDNRSLFSLN 709
Query: 677 DVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTC-------PELPEIPNGWKSPSQPELV 729
+V ++F+ PG + G PR C PELP + P P+++
Sbjct: 710 EV-VEFRCQPGFVMKG------------PRRVKCQALNKWEPELPSCSRVCQPP--PDVL 754
Query: 730 H-------------GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGD 776
H G V Y C PGY + G++ + C WS P+C+ V SC D
Sbjct: 755 HAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCE-VKSCDDFMG 813
Query: 777 VEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPK-WSDRAPKCLLEQL 835
+ R++ +GA V ++CD+GF L GSS C AG W+ P C EQ+
Sbjct: 814 QLLNGRVLFPVNLQLGAKVDFVCDEGFQLKGSSASYC--VLAGMESLWNSSVPVC--EQI 869
Query: 836 KPCHGLSAPENGARSPEK-QLHPAGATIHFSCAP------GYVLKGQASIKCV--PGHPS 886
C NG + + ++ P G T++++C P + L G+++I+C P
Sbjct: 870 F-CPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRCTSDPQGNG 928
Query: 887 HWSDPPPIC 895
WS P P C
Sbjct: 929 VWSSPAPRC 937
Score = 89.7 bits (221), Expect = 1e-17
Identities = 136/562 (24%), Positives = 201/562 (35%), Gaps = 108/562 (19%)
Query: 372 SLHPGGSARFHCATGYQLKGARHLTCLNA-TQPFWDSKEPVC---IAACGGVIRNAT-TG 426
+L G F C G+QLKG+ C+ A + W+S PVC VI N TG
Sbjct: 825 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTG 884
Query: 427 RIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYD 486
+ + FP + N TC G L E D + G+ V + P
Sbjct: 885 KPLEV-FPFGKTVNYTCD--PHPDRGTSFDLIGESTIRCTSDPQ-----GNGVWSSPA-- 934
Query: 487 SYEVEYLPIEGLLSSGKHFF---VELSTDSSGAAAGMALRYEAFQQGH-------CYEPF 536
I G + HF ++ T++S G +L+YE + + C +
Sbjct: 935 ----PRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 990
Query: 537 VKYG------NFSSSTPTYPV------------GTTVEFSCDPGYTLEQGSIIIECV-DP 577
V S TP PV G+ + +SC G+ L G EC+
Sbjct: 991 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLI-GHSSAECILSG 1049
Query: 578 HDPQWNETEPACRAV-CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIR 636
+ W+ P C+ + C T + G +S N E + G +
Sbjct: 1050 NAAHWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGS-----------------VV 1091
Query: 637 VLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQG 696
R PG G ++G+ S ++ + D + S P +
Sbjct: 1092 TYRCNPGS------GGRKVFELVGEPS-------IYCTSNDDQVGIWSGPAPQCI----- 1133
Query: 697 FVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH-GTVVTYQCYPGYQVVGSSVLMCQWD 755
+P T P + NG L VV ++C PG+ + G + CQ
Sbjct: 1134 -------IPNKCTPPN---VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
Query: 756 LTWSEDLPSCQRVTSCHDPGDVEHSRRL-ISSPKFPVGATVQYICDQGFVLMGSSILTCH 814
W +LPSC RV C P DV H+ R F G V Y C+ G+ L G++ + C
Sbjct: 1184 NKWEPELPSCSRV--CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC- 1240
Query: 815 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 874
WS AP C ++K C R GA + F C G+ LKG
Sbjct: 1241 ---TPQGDWSPAAPTC---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKG 1294
Query: 875 QASIKCV-PGHPSHWSDPPPIC 895
++ CV G S W+ P+C
Sbjct: 1295 SSASYCVLAGMESLWNSSVPVC 1316
Score = 85.1 bits (209), Expect = 3e-16
Identities = 135/563 (23%), Positives = 203/563 (36%), Gaps = 110/563 (19%)
Query: 372 SLHPGGSARFHCATGYQLKGARHLTCLNA-TQPFWDSKEPVC---IAACGGVIRNAT-TG 426
+L G F C G+QLKG+ C+ A + W+S PVC VI N TG
Sbjct: 1275 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTG 1334
Query: 427 RIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYD 486
+ + FP + N TC G L E D + G+ V + P
Sbjct: 1335 KPLEV-FPFGKAVNYTCD--PHPDRGTSFDLIGESTIRCTSDPQ-----GNGVWSSPA-- 1384
Query: 487 SYEVEYLPIEGLLSSGKHFF---VELSTDSSGAAAGMALRYEAFQQGH-------CYEPF 536
I G + HF ++ T++S G +L+YE + + C +
Sbjct: 1385 ----PRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 1440
Query: 537 VKYG------NFSSSTPTYPV------------GTTVEFSCDPGYTLEQGSIIIECV-DP 577
V S TP PV G+ + +SC G+ L G EC+
Sbjct: 1441 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLI-GHSSAECILSG 1499
Query: 578 HDPQWNETEPACRAV-CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIR 636
+ W+ P C+ + C T + G +S N E + G + ++ R + ++
Sbjct: 1500 NTAHWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGSVVTYRCNLGSRGRKVFEL- 1557
Query: 637 VLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQG 696
+G + + D + G +SGP
Sbjct: 1558 ---VGEPSIYCTSNDDQV-----GIWSGPAPQC--------------------------- 1582
Query: 697 FVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH-GTVVTYQCYPGYQVVGSSVLMCQWD 755
+ N P P + NG L VV ++C PG+ + G + CQ
Sbjct: 1583 -------IIPNKCTP--PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1633
Query: 756 LTWSEDLPSCQRVTSCHDPGDVEHSRRLIS-SPKFPVGATVQYICDQGFVLMGSSILTCH 814
W +LPSC RV C P ++ H S F G V Y C+ G+ L G++ L C
Sbjct: 1634 NKWEPELPSCSRV--CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC- 1690
Query: 815 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSP-EKQLHPAGATIHFSCAPGYVLK 873
WS AP+C ++ G P P QL GA + F C G+ LK
Sbjct: 1691 ---TPQGDWSPEAPRCAVKSCDDFLG-QLPHGRVLFPLNLQL---GAKVSFVCDEGFRLK 1743
Query: 874 GQASIKCV-PGHPSHWSDPPPIC 895
G + CV G S W++ P+C
Sbjct: 1744 GSSVSHCVLVGMRSLWNNSVPVC 1766
Score = 79.3 bits (194), Expect = 2e-14
Identities = 124/575 (21%), Positives = 198/575 (34%), Gaps = 86/575 (14%)
Query: 356 SCHFPRRPAYGDV-TVTSLHPGGSARFHCATGYQLKGARHLTC-LNATQPFWDSKEPVCI 413
SC P P G V +T + G + C TG++L G C L+ W +K P+C
Sbjct: 1453 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1512
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
G+ G +S + ++ + G+++ FE V
Sbjct: 1513 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV---FELVG---------- 1559
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
P +Y + D G +G A + C
Sbjct: 1560 -------EPSIY---------------------CTSNDDQVGIWSGPA--PQCIIPNKCT 1589
Query: 534 EPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
P V+ G S + + + VEF C PG+ + +G ++C + +W P+C V
Sbjct: 1590 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALN--KWEPELPSCSRV 1646
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGD 652
C G +P+ + + GQ+ + D R + G
Sbjct: 1647 CQPPPEILHG-EHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAV 1705
Query: 653 DLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVI---------HFFE 703
LGQ R F L + + F D G + G + +
Sbjct: 1706 KSCDDFLGQLPHGRVLFPLNLQLG-AKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVP 1764
Query: 704 VPRNDTCPELPEIPNGWKSPS-QPELVHGTVVTYQCYP------GYQVVGSSVLMCQWDL 756
V + CP P I NG + + ++ +G ++Y C P + ++G S + C D
Sbjct: 1765 VCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDP 1824
Query: 757 ----TWSEDLPSCQ---RVTSCHDPGDVEHSRRL--ISSPKFPVGATVQYICDQGFVLMG 807
WS P C+ R C P + I+ +FPVG ++ Y C G+
Sbjct: 1825 HGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKM 1884
Query: 808 SSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCA 867
SI +C + WS C + K C P NG G+T+++SC
Sbjct: 1885 FSI-SCLENLV----WSSVEDNC---RRKSCGPPPEPFNGMVHINTDTQ-FGSTVNYSCN 1935
Query: 868 PGYVLKGQASIKC-VPGHPSHWSDPPPICRAASLD 901
G+ L G S C V G+ W PIC S +
Sbjct: 1936 EGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1970
Score = 67.8 bits (164), Expect = 5e-11
Identities = 52/201 (25%), Positives = 80/201 (39%), Gaps = 18/201 (8%)
Query: 706 RNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD---LTWSEDL 762
R +C P+ NG + + G+ + Y C GY+++GSS C + W +
Sbjct: 100 RRKSCRNPPDPVNGMVHVIKG-IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNET 158
Query: 763 PSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQG------FVLMGSSILTC--H 814
P C R+ P + F G+ V Y C+ G F L+G + C +
Sbjct: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 815 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 874
D Q G WS AP+C++ C + S + L + F C PG+V+KG
Sbjct: 219 DDQVGI--WSGPAPQCIIPN--KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKG 274
Query: 875 QASIKCVPGHPSHWSDPPPIC 895
+KC + W P C
Sbjct: 275 PRRVKCQA--LNKWEPELPSC 293
Score = 67.4 bits (163), Expect = 6e-11
Identities = 121/581 (20%), Positives = 199/581 (34%), Gaps = 100/581 (17%)
Query: 356 SCHFPRRPAYGDVTV-TSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPVCI 413
SC P P G V + T G + + C G++L G+ TCL + WD K P+C
Sbjct: 1906 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1965
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
+ G S ++ + + P+G++L FE V +R I
Sbjct: 1966 IISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL---FELVG-----ERSIY 2017
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
+ D V P +S+ K E+ A+R
Sbjct: 2018 CTSKD-------DQVGVWSSPPPRCISTNKCTAPEVEN---------AIRVP-------- 2053
Query: 534 EPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC 593
GN S T T + F C PG+ + GS ++C + +W P C VC
Sbjct: 2054 ------GNRSFFTLT----EIIRFRCQPGFVMV-GSHTVQCQT--NGRWGPKLPHCSRVC 2100
Query: 594 S-------GEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVL 646
GE T S SP GQ+ + D R + G
Sbjct: 2101 QPPPEILHGEHTLSHQDNFSP--------GQEVFYSCEPSYDLRGAASLHCTPQGDWSP- 2151
Query: 647 TFYDGDDLTARVLGQYSGPRSHFKLFTSM---ADVTIQFQSDPGTSVLGYQQGFVI---- 699
+ T + + G H ++ + + F D G + G +
Sbjct: 2152 ---EAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM 2208
Query: 700 -----HFFEVPRNDTCPELPEIPNGWKSPSQ-PELVHGTVVTYQC--YPG----YQVVGS 747
V CP P I NG + + ++ +G ++Y C +P + ++G
Sbjct: 2209 KALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 2268
Query: 748 SVLMC----QWDLTWSEDLPSCQRVT--SCHDPGDVEHSRRLISSPKFPV-GATVQYICD 800
S + C Q + WS P C+ +C P +++ + + G T+ YICD
Sbjct: 2269 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICD 2328
Query: 801 QGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGA 860
G++L+G + C D+ WS C +++ L K+++ G
Sbjct: 2329 PGYLLVGKGFIFCTDQGI----WSQLDHYC--KEVNCSFPLFMNGISKELEMKKVYHYGD 2382
Query: 861 TIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLD 901
+ C GY L+G +C W P C + + D
Sbjct: 2383 YVTLKCEDGYTLEGSPWSQCQA--DDRWDPPLAKCTSRTHD 2421
Score = 58.9 bits (141), Expect = 2e-08
Identities = 48/174 (27%), Positives = 74/174 (42%), Gaps = 16/174 (9%)
Query: 731 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
GT + Y+C PGY S++ C + W+ C+R + + P V +I +F
Sbjct: 66 GTYLNYECRPGYSGRPFSII-CLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF- 123
Query: 791 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENG-AR 849
G+ ++Y C +G+ L+GSS TC + W + P C PC NG
Sbjct: 124 -GSQIKYSCTKGYRLIGSSSATC-IISGDTVIWDNETPIC---DRIPCGLPPTITNGDFI 178
Query: 850 SPEKQLHPAGATIHFSCAPG------YVLKGQASIKCVPG--HPSHWSDPPPIC 895
S ++ G+ + + C PG + L G+ SI C WS P P C
Sbjct: 179 STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 788 KFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENG 847
+FP+G + Y C G+ SI+ + W+ +C + K C P NG
Sbjct: 62 EFPIGTYLNYECRPGYSGRPFSIICLK-----NSVWTGAKDRC---RRKSCRNPPDPVNG 113
Query: 848 ARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC-VPGHPSHWSDPPPIC 895
K + G+ I +SC GY L G +S C + G W + PIC
Sbjct: 114 MVHVIKGIQ-FGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
>gi|86793036 complement receptor 1 isoform F precursor [Homo sapiens]
Length = 2039
Score = 97.8 bits (242), Expect = 4e-20
Identities = 141/603 (23%), Positives = 228/603 (37%), Gaps = 94/603 (15%)
Query: 357 CHFPRRPAYGDVTVT---SLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVC- 412
C P +G+ T + + PG + C GY L+GA L C Q W + P C
Sbjct: 1197 CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC--TPQGDWSPEAPRCA 1254
Query: 413 IAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLH--------------LH 458
+ +C + GR++ FP N ++ + EG RL L
Sbjct: 1255 VKSCDDFLGQLPHGRVL---FPLNLQLGAKVSFVCD--EGFRLKGSSVSHCVLVGMRSLW 1309
Query: 459 FEKVSLAED---DDRLIIRNGDNVEAPPVYDSY--EVEYL----PIEGL---LSSGKHFF 506
V + E + I NG + P Y E+ Y P G+ L
Sbjct: 1310 NNSVPVCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIR 1369
Query: 507 VELSTDSSGAAAGMALRYE-AFQQGHCYEPFVKYGNFSSSTPT-------YPVGTTVEFS 558
+G + A R E + + GHC P F ++PT +PVGT++ +
Sbjct: 1370 CTSDPHGNGVWSSPAPRCELSVRAGHCKTP----EQFPFASPTIPINDFEFPVGTSLNYE 1425
Query: 559 CDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGR--G 616
C PGY + SI C++ + W+ E CR G + ++ N +G
Sbjct: 1426 CRPGYFGKMFSI--SCLE--NLVWSSVEDNCRRKSCGPPPEPFNGMVHINTDTQFGSTVN 1481
Query: 617 QDC---------------IWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQ 661
C + G +V DK+ + ++ P ++ +GD +
Sbjct: 1482 YSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPI-CEIISCEPPPTIS--NGDFYSNNRTSF 1538
Query: 662 YSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVP-----RNDTCPELPEI 716
++G ++ T D F+ S+ + + + P + C PE+
Sbjct: 1539 HNGTVVTYQCHTG-PDGEQLFELVGERSIYCTSKDDQVGVWSSPPPRCISTNKCTA-PEV 1596
Query: 717 PNGWKSPSQPELVHGT-VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPG 775
N + P T ++ ++C PG+ +VGS + CQ + W LP C RV C P
Sbjct: 1597 ENAIRVPGNRSFFTLTEIIRFRCQPGFVMVGSHTVQCQTNGRWGPKLPHCSRV--CQPPP 1654
Query: 776 DVEHSRRLIS-SPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQ 834
++ H +S F G V Y C+ + L G++ L C WS AP+C ++
Sbjct: 1655 EILHGEHTLSHQDNFSPGQEVFYSCEPSYDLRGAASLHC----TPQGDWSPEAPRCTVKS 1710
Query: 835 LKPCHGLSAPENGARSP-EKQLHPAGATIHFSCAPGYVLKGQASIKCV-PGHPSHWSDPP 892
G P P QL GA + F C G+ LKG+++ CV G + W+
Sbjct: 1711 CDDFLG-QLPHGRVLLPLNLQL---GAKVSFVCDEGFRLKGRSASHCVLAGMKALWNSSV 1766
Query: 893 PIC 895
P+C
Sbjct: 1767 PVC 1769
Score = 97.1 bits (240), Expect = 7e-20
Identities = 128/571 (22%), Positives = 208/571 (36%), Gaps = 91/571 (15%)
Query: 356 SCHFPRRPAYGDV-TVTSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPVCI 413
SC P P G V + + G ++ C GY+L G+ TC+ + WD++ P+C
Sbjct: 103 SCRNPPDPVNGMVHVIKGIQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPICD 162
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
G+ T G +S + ++ + G+++ FE V
Sbjct: 163 RIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKV---FELVG---------- 209
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
P +Y + + D G +G A + C
Sbjct: 210 -------EPSIYCTS---------------------NDDQVGIWSGPAP--QCIIPNKCT 239
Query: 534 EPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
P V+ G S + + + VEF C PG+ + +G ++C + +W P+C V
Sbjct: 240 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALN--KWEPELPSCSRV 296
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIG----PGDVLTF 648
C D + + + GQ+ + D R +R G
Sbjct: 297 CQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEV 355
Query: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGF-VIHFFEVPRN 707
DD +GQ R F + + + F D G + G + V+ E N
Sbjct: 356 KSCDDF----MGQLLNGRVLFPVNLQLG-AKVDFVCDEGFQLKGSSASYCVLAGMESLWN 410
Query: 708 DT--------CPELPEIPNGWKSPSQPELV-HGTVVTYQCYP------GYQVVGSSVLMC 752
+ CP P IPNG + E+ G V Y C P + ++G S + C
Sbjct: 411 SSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKTVNYTCDPHPDRGTSFDLIGESTIRC 470
Query: 753 ----QWDLTWSEDLPSCQRVTSCHDPGDVEHS--RRLISSPKFPVGATVQYICDQGFVLM 806
Q + WS P C + C P + + ++ FP+G +++Y C +
Sbjct: 471 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR 530
Query: 807 GSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSC 866
SI TC D WS C + K C P NG + G+ I++SC
Sbjct: 531 PFSI-TCLDNLV----WSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQ-VGSRINYSC 581
Query: 867 APGYVLKGQASIKCV-PGHPSHWSDPPPICR 896
G+ L G +S +C+ G+ +HWS PPIC+
Sbjct: 582 TTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Score = 94.4 bits (233), Expect = 5e-19
Identities = 128/571 (22%), Positives = 205/571 (35%), Gaps = 91/571 (15%)
Query: 356 SCHFPRRPAYGDV-TVTSLHPGGSARFHCATGYQLKGARHLTC-LNATQPFWDSKEPVCI 413
SC P P G V +T + G + C TG++L G C L+ W +K P+C
Sbjct: 553 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNAAHWSTKPPICQ 612
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
G+ G +S + ++ + G+++ FE V
Sbjct: 613 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNPGSGGRKV---FELVG---------- 659
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
P +Y + + D G +G A + C
Sbjct: 660 -------EPSIYCTS---------------------NDDQVGIWSGPAP--QCIIPNKCT 689
Query: 534 EPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
P V+ G S + + + VEF C PG+ + +G ++C + +W P+C V
Sbjct: 690 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALN--KWEPELPSCSRV 746
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIG----PGDVLTF 648
C D + + + GQ+ + D R +R G
Sbjct: 747 CQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRCTPQGDWSPAAPTCEV 805
Query: 649 YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGF-VIHFFEVPRN 707
DD +GQ R F + + + F D G + G + V+ E N
Sbjct: 806 KSCDDF----MGQLLNGRVLFPVNLQLG-AKVDFVCDEGFQLKGSSASYCVLAGMESLWN 860
Query: 708 DT--------CPELPEIPNGWKSPSQPELV-HGTVVTYQCYP------GYQVVGSSVLMC 752
+ CP P IPNG + E+ G V Y C P + ++G S + C
Sbjct: 861 SSVPVCEQIFCPSPPVIPNGRHTGKPLEVFPFGKAVNYTCDPHPDRGTSFDLIGESTIRC 920
Query: 753 ----QWDLTWSEDLPSCQRVTSCHDPGDVEHS--RRLISSPKFPVGATVQYICDQGFVLM 806
Q + WS P C + C P + + ++ FP+G +++Y C +
Sbjct: 921 TSDPQGNGVWSSPAPRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGR 980
Query: 807 GSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSC 866
SI TC D WS C + K C P NG + G+ I++SC
Sbjct: 981 PFSI-TCLDNLV----WSSPKDVC---KRKSCKTPPDPVNGMVHVITDIQ-VGSRINYSC 1031
Query: 867 APGYVLKGQASIKCV-PGHPSHWSDPPPICR 896
G+ L G +S +C+ G+ +HWS PPIC+
Sbjct: 1032 TTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Score = 89.7 bits (221), Expect = 1e-17
Identities = 136/562 (24%), Positives = 201/562 (35%), Gaps = 108/562 (19%)
Query: 372 SLHPGGSARFHCATGYQLKGARHLTCLNA-TQPFWDSKEPVC---IAACGGVIRNAT-TG 426
+L G F C G+QLKG+ C+ A + W+S PVC VI N TG
Sbjct: 375 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTG 434
Query: 427 RIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYD 486
+ + FP + N TC G L E D + G+ V + P
Sbjct: 435 KPLEV-FPFGKTVNYTCD--PHPDRGTSFDLIGESTIRCTSDPQ-----GNGVWSSPA-- 484
Query: 487 SYEVEYLPIEGLLSSGKHFF---VELSTDSSGAAAGMALRYEAFQQGH-------CYEPF 536
I G + HF ++ T++S G +L+YE + + C +
Sbjct: 485 ----PRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 540
Query: 537 VKYG------NFSSSTPTYPV------------GTTVEFSCDPGYTLEQGSIIIECV-DP 577
V S TP PV G+ + +SC G+ L G EC+
Sbjct: 541 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLI-GHSSAECILSG 599
Query: 578 HDPQWNETEPACRAV-CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIR 636
+ W+ P C+ + C T + G +S N E + G +
Sbjct: 600 NAAHWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGS-----------------VV 641
Query: 637 VLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQG 696
R PG G ++G+ S ++ + D + S P +
Sbjct: 642 TYRCNPGS------GGRKVFELVGEPS-------IYCTSNDDQVGIWSGPAPQCI----- 683
Query: 697 FVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH-GTVVTYQCYPGYQVVGSSVLMCQWD 755
+P T P + NG L VV ++C PG+ + G + CQ
Sbjct: 684 -------IPNKCTPPN---VENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 733
Query: 756 LTWSEDLPSCQRVTSCHDPGDVEHSRRL-ISSPKFPVGATVQYICDQGFVLMGSSILTCH 814
W +LPSC RV C P DV H+ R F G V Y C+ G+ L G++ + C
Sbjct: 734 NKWEPELPSCSRV--CQPPPDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGAASMRC- 790
Query: 815 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 874
WS AP C ++K C R GA + F C G+ LKG
Sbjct: 791 ---TPQGDWSPAAPTC---EVKSCDDFMGQLLNGRVLFPVNLQLGAKVDFVCDEGFQLKG 844
Query: 875 QASIKCV-PGHPSHWSDPPPIC 895
++ CV G S W+ P+C
Sbjct: 845 SSASYCVLAGMESLWNSSVPVC 866
Score = 85.1 bits (209), Expect = 3e-16
Identities = 135/563 (23%), Positives = 203/563 (36%), Gaps = 110/563 (19%)
Query: 372 SLHPGGSARFHCATGYQLKGARHLTCLNA-TQPFWDSKEPVC---IAACGGVIRNAT-TG 426
+L G F C G+QLKG+ C+ A + W+S PVC VI N TG
Sbjct: 825 NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCEQIFCPSPPVIPNGRHTG 884
Query: 427 RIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYD 486
+ + FP + N TC G L E D + G+ V + P
Sbjct: 885 KPLEV-FPFGKAVNYTCD--PHPDRGTSFDLIGESTIRCTSDPQ-----GNGVWSSPA-- 934
Query: 487 SYEVEYLPIEGLLSSGKHFF---VELSTDSSGAAAGMALRYEAFQQGH-------CYEPF 536
I G + HF ++ T++S G +L+YE + + C +
Sbjct: 935 ----PRCGILGHCQAPDHFLFAKLKTQTNASDFPIGTSLKYECRPEYYGRPFSITCLDNL 990
Query: 537 VKYG------NFSSSTPTYPV------------GTTVEFSCDPGYTLEQGSIIIECV-DP 577
V S TP PV G+ + +SC G+ L G EC+
Sbjct: 991 VWSSPKDVCKRKSCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLI-GHSSAECILSG 1049
Query: 578 HDPQWNETEPACRAV-CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIR 636
+ W+ P C+ + C T + G +S N E + G + ++ R + ++
Sbjct: 1050 NTAHWSTKPPICQRIPCGLPPTIANGDFISTN-RENFHYGSVVTYRCNLGSRGRKVFEL- 1107
Query: 637 VLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQG 696
+G + + D + G +SGP
Sbjct: 1108 ---VGEPSIYCTSNDDQV-----GIWSGPAPQC--------------------------- 1132
Query: 697 FVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVH-GTVVTYQCYPGYQVVGSSVLMCQWD 755
+ N P P + NG L VV ++C PG+ + G + CQ
Sbjct: 1133 -------IIPNKCTP--PNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKGPRRVKCQAL 1183
Query: 756 LTWSEDLPSCQRVTSCHDPGDVEHSRRLIS-SPKFPVGATVQYICDQGFVLMGSSILTCH 814
W +LPSC RV C P ++ H S F G V Y C+ G+ L G++ L C
Sbjct: 1184 NKWEPELPSCSRV--CQPPPEILHGEHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHC- 1240
Query: 815 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSP-EKQLHPAGATIHFSCAPGYVLK 873
WS AP+C ++ G P P QL GA + F C G+ LK
Sbjct: 1241 ---TPQGDWSPEAPRCAVKSCDDFLG-QLPHGRVLFPLNLQL---GAKVSFVCDEGFRLK 1293
Query: 874 GQASIKCV-PGHPSHWSDPPPIC 895
G + CV G S W++ P+C
Sbjct: 1294 GSSVSHCVLVGMRSLWNNSVPVC 1316
Score = 79.3 bits (194), Expect = 2e-14
Identities = 124/575 (21%), Positives = 198/575 (34%), Gaps = 86/575 (14%)
Query: 356 SCHFPRRPAYGDV-TVTSLHPGGSARFHCATGYQLKGARHLTC-LNATQPFWDSKEPVCI 413
SC P P G V +T + G + C TG++L G C L+ W +K P+C
Sbjct: 1003 SCKTPPDPVNGMVHVITDIQVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSTKPPICQ 1062
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
G+ G +S + ++ + G+++ FE V
Sbjct: 1063 RIPCGLPPTIANGDFISTNRENFHYGSVVTYRCNLGSRGRKV---FELVG---------- 1109
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
P +Y + D G +G A + C
Sbjct: 1110 -------EPSIY---------------------CTSNDDQVGIWSGPA--PQCIIPNKCT 1139
Query: 534 EPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
P V+ G S + + + VEF C PG+ + +G ++C + +W P+C V
Sbjct: 1140 PPNVENGILVSDNRSLFSLNEVVEFRCQPGFVM-KGPRRVKCQALN--KWEPELPSCSRV 1196
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGD 652
C G +P+ + + GQ+ + D R + G
Sbjct: 1197 CQPPPEILHG-EHTPSHQDNFSPGQEVFYSCEPGYDLRGAASLHCTPQGDWSPEAPRCAV 1255
Query: 653 DLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVI---------HFFE 703
LGQ R F L + + F D G + G + +
Sbjct: 1256 KSCDDFLGQLPHGRVLFPLNLQLG-AKVSFVCDEGFRLKGSSVSHCVLVGMRSLWNNSVP 1314
Query: 704 VPRNDTCPELPEIPNGWKSPS-QPELVHGTVVTYQCYP------GYQVVGSSVLMCQWDL 756
V + CP P I NG + + ++ +G ++Y C P + ++G S + C D
Sbjct: 1315 VCEHIFCPNPPAILNGRHTGTPSGDIPYGKEISYTCDPHPDRGMTFNLIGESTIRCTSDP 1374
Query: 757 ----TWSEDLPSCQ---RVTSCHDPGDVEHSRRL--ISSPKFPVGATVQYICDQGFVLMG 807
WS P C+ R C P + I+ +FPVG ++ Y C G+
Sbjct: 1375 HGNGVWSSPAPRCELSVRAGHCKTPEQFPFASPTIPINDFEFPVGTSLNYECRPGYFGKM 1434
Query: 808 SSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCA 867
SI +C + WS C + K C P NG G+T+++SC
Sbjct: 1435 FSI-SCLENLV----WSSVEDNC---RRKSCGPPPEPFNGMVHINTDTQ-FGSTVNYSCN 1485
Query: 868 PGYVLKGQASIKC-VPGHPSHWSDPPPICRAASLD 901
G+ L G S C V G+ W PIC S +
Sbjct: 1486 EGFRLIGSPSTTCLVSGNNVTWDKKAPICEIISCE 1520
Score = 67.8 bits (164), Expect = 5e-11
Identities = 52/201 (25%), Positives = 80/201 (39%), Gaps = 18/201 (8%)
Query: 706 RNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD---LTWSEDL 762
R +C P+ NG + + G+ + Y C GY+++GSS C + W +
Sbjct: 100 RRKSCRNPPDPVNGMVHVIKG-IQFGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNET 158
Query: 763 PSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQG------FVLMGSSILTC--H 814
P C R+ P + F G+ V Y C+ G F L+G + C +
Sbjct: 159 PICDRIPCGLPPTITNGDFISTNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSN 218
Query: 815 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 874
D Q G WS AP+C++ C + S + L + F C PG+V+KG
Sbjct: 219 DDQVGI--WSGPAPQCIIPN--KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFVMKG 274
Query: 875 QASIKCVPGHPSHWSDPPPIC 895
+KC + W P C
Sbjct: 275 PRRVKCQA--LNKWEPELPSC 293
Score = 67.4 bits (163), Expect = 6e-11
Identities = 121/581 (20%), Positives = 199/581 (34%), Gaps = 100/581 (17%)
Query: 356 SCHFPRRPAYGDVTV-TSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPVCI 413
SC P P G V + T G + + C G++L G+ TCL + WD K P+C
Sbjct: 1456 SCGPPPEPFNGMVHINTDTQFGSTVNYSCNEGFRLIGSPSTTCLVSGNNVTWDKKAPICE 1515
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLII 473
+ G S ++ + + P+G++L FE V +R I
Sbjct: 1516 IISCEPPPTISNGDFYSNNRTSFHNGTVVTYQCHTGPDGEQL---FELVG-----ERSIY 1567
Query: 474 RNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCY 533
+ D V P +S+ K E+ A+R
Sbjct: 1568 CTSKD-------DQVGVWSSPPPRCISTNKCTAPEVEN---------AIRVP-------- 1603
Query: 534 EPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC 593
GN S T T + F C PG+ + GS ++C + +W P C VC
Sbjct: 1604 ------GNRSFFTLT----EIIRFRCQPGFVMV-GSHTVQCQT--NGRWGPKLPHCSRVC 1650
Query: 594 S-------GEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVL 646
GE T S SP GQ+ + D R + G
Sbjct: 1651 QPPPEILHGEHTLSHQDNFSP--------GQEVFYSCEPSYDLRGAASLHCTPQGDWSP- 1701
Query: 647 TFYDGDDLTARVLGQYSGPRSHFKLFTSM---ADVTIQFQSDPGTSVLGYQQGFVI---- 699
+ T + + G H ++ + + F D G + G +
Sbjct: 1702 ---EAPRCTVKSCDDFLGQLPHGRVLLPLNLQLGAKVSFVCDEGFRLKGRSASHCVLAGM 1758
Query: 700 -----HFFEVPRNDTCPELPEIPNGWKSPSQ-PELVHGTVVTYQC--YPG----YQVVGS 747
V CP P I NG + + ++ +G ++Y C +P + ++G
Sbjct: 1759 KALWNSSVPVCEQIFCPNPPAILNGRHTGTPFGDIPYGKEISYACDTHPDRGMTFNLIGE 1818
Query: 748 SVLMC----QWDLTWSEDLPSCQRVT--SCHDPGDVEHSRRLISSPKFPV-GATVQYICD 800
S + C Q + WS P C+ +C P +++ + + G T+ YICD
Sbjct: 1819 SSIRCTSDPQGNGVWSSPAPRCELSVPAACPHPPKIQNGHYIGGHVSLYLPGMTISYICD 1878
Query: 801 QGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGA 860
G++L+G + C D+ WS C +++ L K+++ G
Sbjct: 1879 PGYLLVGKGFIFCTDQGI----WSQLDHYC--KEVNCSFPLFMNGISKELEMKKVYHYGD 1932
Query: 861 TIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLD 901
+ C GY L+G +C W P C + + D
Sbjct: 1933 YVTLKCEDGYTLEGSPWSQCQA--DDRWDPPLAKCTSRTHD 1971
Score = 58.9 bits (141), Expect = 2e-08
Identities = 48/174 (27%), Positives = 74/174 (42%), Gaps = 16/174 (9%)
Query: 731 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
GT + Y+C PGY S++ C + W+ C+R + + P V +I +F
Sbjct: 66 GTYLNYECRPGYSGRPFSII-CLKNSVWTGAKDRCRRKSCRNPPDPVNGMVHVIKGIQF- 123
Query: 791 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENG-AR 849
G+ ++Y C +G+ L+GSS TC + W + P C PC NG
Sbjct: 124 -GSQIKYSCTKGYRLIGSSSATC-IISGDTVIWDNETPIC---DRIPCGLPPTITNGDFI 178
Query: 850 SPEKQLHPAGATIHFSCAPG------YVLKGQASIKCVPG--HPSHWSDPPPIC 895
S ++ G+ + + C PG + L G+ SI C WS P P C
Sbjct: 179 STNRENFHYGSVVTYRCNPGSGGRKVFELVGEPSIYCTSNDDQVGIWSGPAPQC 232
Score = 43.1 bits (100), Expect = 0.001
Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 788 KFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENG 847
+FP+G + Y C G+ SI+ + W+ +C + K C P NG
Sbjct: 62 EFPIGTYLNYECRPGYSGRPFSIICLK-----NSVWTGAKDRC---RRKSCRNPPDPVNG 113
Query: 848 ARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC-VPGHPSHWSDPPPIC 895
K + G+ I +SC GY L G +S C + G W + PIC
Sbjct: 114 MVHVIKGIQ-FGSQIKYSCTKGYRLIGSSSATCIISGDTVIWDNETPIC 161
>gi|148922949 complement component (3b/4b) receptor 1-like [Homo
sapiens]
Length = 569
Score = 95.9 bits (237), Expect = 2e-19
Identities = 94/368 (25%), Positives = 148/368 (40%), Gaps = 41/368 (11%)
Query: 555 VEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPAC-RAVCSGEITDSAGVVLSPNWPEPY 613
+++SC GY L S + + W+ P C R +C T + G S + E +
Sbjct: 119 IKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSIS-REYF 177
Query: 614 GRGQ----DCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHF 669
G C G ++ ++ + + D + + G + + + P
Sbjct: 178 HYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQCIIPNKCTPPNVEN 237
Query: 670 KLFTS------MADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSP 723
+ S + ++F+ PG + G H N PELP + P
Sbjct: 238 GILVSDNRSLFSLNEVVEFRCQPGFGMKGPS-----HVKCQALNKWEPELPSCSRVCQPP 292
Query: 724 SQPELVH-------------GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTS 770
P+++H G V Y C PGY + GS+ L C WS P C+ V S
Sbjct: 293 --PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCE-VKS 349
Query: 771 CHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPK-WSDRAPK 829
C D + ++ +GA V ++CD+GF L GSS C AG W+ P
Sbjct: 350 CDDFLGQLPNGHVLFPLNLQLGAKVDFVCDEGFQLKGSSASYC--VLAGMESLWNSSVPV 407
Query: 830 CLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCV-PGHPSHW 888
C + K C P NG +H G+ I++SC G+ L G +S +C+ G+ +HW
Sbjct: 408 C---ERKSCETPPVPVNGMVHVITDIH-VGSRINYSCTTGHRLIGHSSAECILSGNTAHW 463
Query: 889 SDPPPICR 896
S PPIC+
Sbjct: 464 SMKPPICQ 471
Score = 85.5 bits (210), Expect = 2e-16
Identities = 60/172 (34%), Positives = 80/172 (46%), Gaps = 13/172 (7%)
Query: 733 VVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRL-ISSPKFPV 791
VV ++C PG+ + G S + CQ W +LPSC RV C P DV H+ R F
Sbjct: 253 VVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRV--CQPPPDVLHAERTQRDKDNFSP 310
Query: 792 GATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHG-LSAPENGARS 850
G V Y C+ G+ L GS+ L C WS AP+C ++K C L NG
Sbjct: 311 GQEVFYSCEPGYDLRGSTYLHC----TPQGDWSPAAPRC---EVKSCDDFLGQLPNGHVL 363
Query: 851 PEKQLHPAGATIHFSCAPGYVLKGQASIKCV-PGHPSHWSDPPPICRAASLD 901
L GA + F C G+ LKG ++ CV G S W+ P+C S +
Sbjct: 364 FPLNLQ-LGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCE 414
Score = 65.1 bits (157), Expect = 3e-10
Identities = 48/199 (24%), Positives = 77/199 (38%), Gaps = 14/199 (7%)
Query: 706 RNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD---LTWSEDL 762
+ +C P+ NG + ++ + + Y C GY+++GSS C + W
Sbjct: 92 KRKSCRNPPDPVNGMAHVIK-DIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKT 150
Query: 763 PSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQG------FVLMGSSILTCHDR 816
P C R+ P IS F G+ V Y C+ G F L+G + C +
Sbjct: 151 PVCDRIICGLPPTIANGDFTSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSK 210
Query: 817 QAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQA 876
WS AP+C++ C + S + L + F C PG+ +KG +
Sbjct: 211 DDQVGIWSGPAPQCIIPN--KCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPS 268
Query: 877 SIKCVPGHPSHWSDPPPIC 895
+KC + W P C
Sbjct: 269 HVKCQA--LNKWEPELPSC 285
Score = 62.4 bits (150), Expect = 2e-09
Identities = 106/498 (21%), Positives = 165/498 (33%), Gaps = 70/498 (14%)
Query: 356 SCHFPRRPAYGDV-TVTSLHPGGSARFHCATGYQLKGARHLTCL-NATQPFWDSKEPVCI 413
SC P P G + + ++ C GY+L G+ TC+ + WD+K PVC
Sbjct: 95 SCRNPPDPVNGMAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCD 154
Query: 414 AACGGVIRNATTGRIVSPGFPG-NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
G+ G S +Y + +T H L G R FE V
Sbjct: 155 RIICGLPPTIANGDFTSISREYFHYGSVVTYHCNL----GSRGKKVFELVG--------- 201
Query: 473 IRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHC 532
P +Y + + D G +G A + C
Sbjct: 202 --------EPSIYCTSK---------------------DDQVGIWSGPAP--QCIIPNKC 230
Query: 533 YEPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRA 591
P V+ G S + + + VEF C PG+ ++ G ++C + +W P+C
Sbjct: 231 TPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMK-GPSHVKCQALN--KWEPELPSCSR 287
Query: 592 VCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDG 651
VC D + + + GQ+ + D R + G
Sbjct: 288 VCQPP-PDVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCE 346
Query: 652 DDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGF-VIHFFEVPRNDTC 710
LGQ F L + + F D G + G + V+ E N +
Sbjct: 347 VKSCDDFLGQLPNGHVLFPLNLQLG-AKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSV 405
Query: 711 P-------ELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWD---LTWSE 760
P E P +P ++ G+ + Y C G++++G S C WS
Sbjct: 406 PVCERKSCETPPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSM 465
Query: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICD------QGFVLMGSSILTCH 814
P CQ++ + P + P G V Y CD F L+G S +
Sbjct: 466 KPPICQQIFCPNPPAILNGRHTGTPLGDIPYGKEVSYTCDPHPDRGMTFNLIGESTIRRT 525
Query: 815 DRQAGSPKWSDRAPKCLL 832
G+ WS AP+C L
Sbjct: 526 SEPHGNGVWSSPAPRCEL 543
Score = 53.9 bits (128), Expect = 7e-07
Identities = 44/175 (25%), Positives = 74/175 (42%), Gaps = 18/175 (10%)
Query: 731 GTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFP 790
GT + Y+C PGY S++ C + W+ C+R + + P V +I +F
Sbjct: 58 GTYLNYECRPGYSGRPFSII-CLKNSVWTSAKDKCKRKSCRNPPDPVNGMAHVIKDIQF- 115
Query: 791 VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKC--LLEQLKPCHGLSAPENGA 848
+ ++Y C +G+ L+GSS TC + W ++ P C ++ L P +
Sbjct: 116 -RSQIKYSCPKGYRLIGSSSATC-IISGNTVIWDNKTPVCDRIICGLPP----TIANGDF 169
Query: 849 RSPEKQLHPAGATIHFSCAPG------YVLKGQASIKCV--PGHPSHWSDPPPIC 895
S ++ G+ + + C G + L G+ SI C WS P P C
Sbjct: 170 TSISREYFHYGSVVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWSGPAPQC 224
Score = 43.1 bits (100), Expect = 0.001
Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 10/109 (9%)
Query: 788 KFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENG 847
+FP+G + Y C G+ SI+ + W+ KC + K C P NG
Sbjct: 54 EFPIGTYLNYECRPGYSGRPFSIICLK-----NSVWTSAKDKC---KRKSCRNPPDPVNG 105
Query: 848 ARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC-VPGHPSHWSDPPPIC 895
K + + I +SC GY L G +S C + G+ W + P+C
Sbjct: 106 MAHVIKDIQ-FRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVC 153
>gi|42544177 complement component (3d/Epstein Barr virus) receptor 2
isoform 2 [Homo sapiens]
Length = 1033
Score = 91.7 bits (226), Expect = 3e-18
Identities = 93/391 (23%), Positives = 152/391 (38%), Gaps = 64/391 (16%)
Query: 543 SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAG 602
S Y TV F C G+TL+ GS I C D W+ P C + S
Sbjct: 614 SGKEAPYFYNDTVTFKCYSGFTLK-GSSQIRC--KADNTWDPEIPVCEKETCQHVRQSLQ 670
Query: 603 VVLSPNWPE---------------PYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLT 647
+ + + E Y QD G+ K+I L +V+ P V+
Sbjct: 671 ELPAGSRVELVNTSCQDGYQLTGHAYQMCQDAENGIWF---KKIPL-CKVIHCHPPPVI- 725
Query: 648 FYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQ------------ 695
V G+++G + L+ + + ++ D G +LG ++
Sbjct: 726 ----------VNGKHTGMMAENFLYGN----EVSYECDQGFYLLGEKKLQCRSDSKGHGS 771
Query: 696 --GFVIHFFEVPRNDTCPELPEIPNGWK-SPSQPELVHGTVVTYQCYPGYQVVGSSVLMC 752
G P CP PE+ +G+K + + H +V C PG+ + GS V+ C
Sbjct: 772 WSGPSPQCLRSPPVTRCPN-PEVKHGYKLNKTHSAYSHNDIVYVDCNPGFIMNGSRVIRC 830
Query: 753 QWDLTWSEDLPSC--QRVTSCHDPGDVEHSRRLISS-PKFPVGATVQYICDQGFVLMGSS 809
D TW +P+C + C P + + +F G ++ Y CDQG++L+G +
Sbjct: 831 HTDNTWVPGVPTCIKKAFIGCPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEA 890
Query: 810 ILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPG 869
+L C WS AP C + + G ++++ GA + C G
Sbjct: 891 LLLC----THEGTWSQPAPHCKEVNCSSPADMDGIQKGLE--PRKMYQYGAVVTLECEDG 944
Query: 870 YVLKGQASIKCVPGHPSHWSDPPPICRAASL 900
Y+L+G +C H W+ P +CR+ SL
Sbjct: 945 YMLEGSPQSQCQSDH--QWNPPLAVCRSRSL 973
Score = 83.2 bits (204), Expect = 1e-15
Identities = 94/383 (24%), Positives = 155/383 (40%), Gaps = 74/383 (19%)
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACR-AVCSGE----ITDSAGVVLS 606
GT++++SC+PGY L G I+C + W P C+ A C +T +
Sbjct: 432 GTSIKYSCNPGYVLV-GEESIQCTS--EGVWTPPVPQCKVAACEATGRQLLTKPQHQFVR 488
Query: 607 PNWPEPYGRGQDCIWGVHVEEDKRI--MLDIRVLR---IGPGDVLTFYDG-------DDL 654
P+ G G V+ E I ++IR+ + P V+ Y+G +D
Sbjct: 489 PDVNSSCGEGYKLSGSVYQECQGTIPWFMEIRLCKEITCPPPPVI--YNGAHTGSSLEDF 546
Query: 655 TARVLGQYS---GPRSHFKLFTSMADVTIQFQSDP---GT----------SVLGYQQGFV 698
Y+ GP + F+ + + TI+ S+ GT S+L Q V
Sbjct: 547 PYGTTVTYTCNPGPERGVE-FSLIGESTIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHV 605
Query: 699 IHFFEVPRNDTCPELPEIPNGWK-SPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLT 757
I NG+K S + + VT++CY G+ + GSS + C+ D T
Sbjct: 606 ----------------HIANGYKISGKEAPYFYNDTVTFKCYSGFTLKGSSQIRCKADNT 649
Query: 758 WSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYI---CDQGFVLMGSSILTCH 814
W ++P C++ T +H R+ S + P G+ V+ + C G+ L G + C
Sbjct: 650 WDPEIPVCEKET-------CQHVRQ--SLQELPAGSRVELVNTSCQDGYQLTGHAYQMCQ 700
Query: 815 DRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKG 874
D + G W + P C + P + ++ E L+ G + + C G+ L G
Sbjct: 701 DAENGI--WFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLY--GNEVSYECDQGFYLLG 756
Query: 875 QASIKCVPGHPSH--WSDPPPIC 895
+ ++C H WS P P C
Sbjct: 757 EKKLQCRSDSKGHGSWSGPSPQC 779
Score = 77.8 bits (190), Expect = 5e-14
Identities = 60/211 (28%), Positives = 93/211 (44%), Gaps = 19/211 (9%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMC----QWDLTWSEDLPS 764
+C P I NG S + GTV+ Y C ++++G L+C + D TW + P
Sbjct: 22 SCGSPPPILNGRISYYSTPIAVGTVIRYSCSGTFRLIGEKSLLCITKDKVDGTWDKPAPK 81
Query: 765 CQ---RVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSP 821
C+ + +SC +P V ++ S + G +V + C F + G+ + C QA +
Sbjct: 82 CEYFNKYSSCPEP-IVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWC---QANNM 137
Query: 822 KWSDRAPKCLLEQLKPCHGLSAPENGARSPEK--QLHPAGATIHFSCAPGYVLKGQASIK 879
R P C+ C L NG + E + P G ++ +SC GY+L G+ I
Sbjct: 138 WGPTRLPTCVSVFPLECPALPMIHNGHHTSENVGSIAP-GLSVTYSCESGYLLVGEKIIN 196
Query: 880 CVPGHPSHWSDPPPIC---RAASLDGFYNSR 907
C+ WS PP C R SL F N +
Sbjct: 197 CLSS--GKWSAVPPTCEEARCKSLGRFPNGK 225
Score = 77.8 bits (190), Expect = 5e-14
Identities = 58/191 (30%), Positives = 85/191 (44%), Gaps = 18/191 (9%)
Query: 709 TCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSED-LPSCQR 767
+CPE P +P G+K HG VT+ C + + G+ + CQ + W LP+C
Sbjct: 90 SCPE-PIVPGGYKIRGSTPYRHGDSVTFACKTNFSMNGNKSVWCQANNMWGPTRLPTCVS 148
Query: 768 VTSCHDPG-----DVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPK 822
V P + H+ + S G +V Y C+ G++L+G I+ C S K
Sbjct: 149 VFPLECPALPMIHNGHHTSENVGS--IAPGLSVTYSCESGYLLVGEKIINC----LSSGK 202
Query: 823 WSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCV- 881
WS P C E+ + C L NG + E + G T +F C GY L+G S +CV
Sbjct: 203 WSAVPPTC--EEAR-CKSLGRFPNG-KVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVI 258
Query: 882 PGHPSHWSDPP 892
G W+ P
Sbjct: 259 AGQGVAWTKMP 269
Score = 77.4 bits (189), Expect = 6e-14
Identities = 142/578 (24%), Positives = 207/578 (35%), Gaps = 83/578 (14%)
Query: 370 VTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIV 429
V S+ PG S + C +GY L G + + CL++ + W + P C A + G++
Sbjct: 170 VGSIAPGLSVTYSCESGYLLVGEKIINCLSSGK--WSAVPPTCEEARCKSLGRFPNGKVK 227
Query: 430 SPGFPG-NYSNNLTCH--WLLEAPEGQRLHLH-----FEKVSLAED----------DDRL 471
P + N C + L+ P R + + K+ + E+ + R
Sbjct: 228 EPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQGVAWTKMPVCEEIFCPSPPPILNGRH 287
Query: 472 IIRNGDNVEAPPVYDSYEVEYLPIEG---LLSSGKHFFVELSTDSSGAAAGMALRYEAFQ 528
I + NV + +Y + P EG +L + + +G +G A R E
Sbjct: 288 IGNSLANVSYGSIV-TYTCDPDPEEGVNFILIGESTLRCTVDSQKTGTWSGPAPRCELST 346
Query: 529 QG-HCYEPFVKYGNF-SSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETE 586
C P + G S Y TV F+C G+TL+ GS I C W +
Sbjct: 347 SAVQCPHPQILRGRMVSGQKDRYTYNDTVIFACMFGFTLK-GSKQIRC--NAQGTWEPSA 403
Query: 587 PACRAVC-------SGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLR 639
P C C +G+ D V P Y C G + ++ I +
Sbjct: 404 PVCEKECQAPPNILNGQKEDRHMVRFDPGTSIKYS----CNPGYVLVGEESIQCTSEGVW 459
Query: 640 IGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQ--QGF 697
P + T R L + P+ F DV S YQ QG
Sbjct: 460 TPPVPQCKVA-ACEATGRQL--LTKPQHQFV----RPDVNSSCGEGYKLSGSVYQECQGT 512
Query: 698 VIHFFEVP--RNDTCPELPEIPNGWKSPSQPE-LVHGTVVTYQCYPG------YQVVGSS 748
+ F E+ + TCP P I NG + S E +GT VTY C PG + ++G S
Sbjct: 513 IPWFMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGES 572
Query: 749 VLMC----QWDLTWSEDLPSCQRVTSCHDPGDVEHSRRL-ISSPKFPV--GATVQYICDQ 801
+ C Q TWS P C+ V + IS + P TV + C
Sbjct: 573 TIRCTSNDQERGTWSGPAPLCKLSLLAVQCSHVHIANGYKISGKEAPYFYNDTVTFKCYS 632
Query: 802 GFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGAT 861
GF L GSS + C W P C E + R ++L PAG+
Sbjct: 633 GFTLKGSSQIRCK----ADNTWDPEIPVCEKETCQH----------VRQSLQEL-PAGSR 677
Query: 862 IHF---SCAPGYVLKGQASIKCVPGHPSHWSDPPPICR 896
+ SC GY L G A C W P+C+
Sbjct: 678 VELVNTSCQDGYQLTGHAYQMCQDAENGIWFKKIPLCK 715
Score = 73.2 bits (178), Expect = 1e-12
Identities = 56/207 (27%), Positives = 89/207 (42%), Gaps = 34/207 (16%)
Query: 710 CPELPEIPNGWKSPSQP-ELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
C P I NG K GT + Y C PGY +VG + C + W+ +P C +V
Sbjct: 410 CQAPPNILNGQKEDRHMVRFDPGTSIKYSCNPGYVLVGEESIQCTSEGVWTPPVPQC-KV 468
Query: 769 TSCHDPGDVEHSRRLISSPKFP-VGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA 827
+C G R+L++ P+ V V C +G+ L GS C G+ W
Sbjct: 469 AACEATG-----RQLLTKPQHQFVRPDVNSSCGEGYKLSGSVYQECQ----GTIPW---- 515
Query: 828 PKCLLEQLKPCHGLSAPE-----NGARSPEK-QLHPAGATIHFSCAPG------YVLKGQ 875
+++ C ++ P NGA + + P G T+ ++C PG + L G+
Sbjct: 516 ----FMEIRLCKEITCPPPPVIYNGAHTGSSLEDFPYGTTVTYTCNPGPERGVEFSLIGE 571
Query: 876 ASIKCVPGHPSH--WSDPPPICRAASL 900
++I+C WS P P+C+ + L
Sbjct: 572 STIRCTSNDQERGTWSGPAPLCKLSLL 598
Score = 64.3 bits (155), Expect = 5e-10
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 7/130 (5%)
Query: 710 CPELPEIPNGWKSPSQ-PELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
CP P+ PNG + G + Y C GY +VG ++L+C + TWS+ P C+ V
Sbjct: 851 CPPPPKTPNGNHTGGNIARFSPGMSILYSCDQGYLLVGEALLLCTHEGTWSQPAPHCKEV 910
Query: 769 TSCHDPGDVEHSRRLISSPK-FPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRA 827
+C P D++ ++ + K + GA V C+ G++L GS C +W+
Sbjct: 911 -NCSSPADMDGIQKGLEPRKMYQYGAVVTLECEDGYMLEGSPQSQCQ----SDHQWNPPL 965
Query: 828 PKCLLEQLKP 837
C L P
Sbjct: 966 AVCRSRSLAP 975
Score = 63.5 bits (153), Expect = 9e-10
Identities = 53/200 (26%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 710 CPELPEIPNGWK-SPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRV 768
CP LP I NG S + + G VTY C GY +VG ++ C WS P+C+
Sbjct: 154 CPALPMIHNGHHTSENVGSIAPGLSVTYSCESGYLLVGEKIINCLSSGKWSAVPPTCEE- 212
Query: 769 TSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAP 828
C G + ++ P VG T + CD+G+ L G C G W+ + P
Sbjct: 213 ARCKSLGRFPNG-KVKEPPILRVGVTANFFCDEGYRLQGPPSSRCVIAGQG-VAWT-KMP 269
Query: 829 KCLLEQLKPCHGLSAPENGARSPEKQLHPA-GATIHFSCAP------GYVLKGQASIKCV 881
C E++ C NG + + G+ + ++C P ++L G+++++C
Sbjct: 270 VC--EEIF-CPSPPPILNGRHIGNSLANVSYGSIVTYTCDPDPEEGVNFILIGESTLRCT 326
Query: 882 --PGHPSHWSDPPPICRAAS 899
WS P P C ++
Sbjct: 327 VDSQKTGTWSGPAPRCELST 346
Score = 37.4 bits (85), Expect = 0.071
Identities = 59/263 (22%), Positives = 95/263 (36%), Gaps = 44/263 (16%)
Query: 383 CATGYQLKGARHLTCLNATQPFWDSKEPVC-IAACGG---VIRNATTGRIVSPGFPGNYS 438
C GYQL G + C +A W K P+C + C ++ TG + GN
Sbjct: 685 CQDGYQLTGHAYQMCQDAENGIWFKKIPLCKVIHCHPPPVIVNGKHTGMMAENFLYGNEV 744
Query: 439 NNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDN---VEAPPV----------- 484
+ E +G L L +K+ D +G + + +PPV
Sbjct: 745 S-------YECDQGFYL-LGEKKLQCRSDSKGHGSWSGPSPQCLRSPPVTRCPNPEVKHG 796
Query: 485 ---------YDSYEVEYLPIE-GLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYE 534
Y ++ Y+ G + +G + TD++ +AF G
Sbjct: 797 YKLNKTHSAYSHNDIVYVDCNPGFIMNGSRV-IRCHTDNTWVPGVPTCIKKAFI-GCPPP 854
Query: 535 PFVKYGNFSSST-PTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC 593
P GN + + G ++ +SCD GY L G ++ C H+ W++ P C+ V
Sbjct: 855 PKTPNGNHTGGNIARFSPGMSILYSCDQGYLL-VGEALLLCT--HEGTWSQPAPHCKEVN 911
Query: 594 SGEITDSAGVV--LSPNWPEPYG 614
D G+ L P YG
Sbjct: 912 CSSPADMDGIQKGLEPRKMYQYG 934
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 89.0 bits (219), Expect = 2e-17
Identities = 108/479 (22%), Positives = 183/479 (38%), Gaps = 88/479 (18%)
Query: 244 CSWNFSGPEGSLDSPTDLSSPTDV--GLDCFFYISVYPGYGVEIKVQNISLREGETVTVE 301
C + + G + SP + P D +C + I+V G+ V + Q + ++ +
Sbjct: 464 CGGDMNKDAGQIQSP---NYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 302 GL---GGPDPLPLANQSFLL-------RGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQ 351
L GP +S L+ + + ++S +++ ++F S F ++
Sbjct: 521 YLEVRDGP-----TEESALIGHFCGYEKPEDVKSSSNRLWMKFVS-DGSINKAGFAANFF 574
Query: 352 AYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPV 411
+ C +P V +L GS + C GY+L + +
Sbjct: 575 KEVDECSWPDHGGCEHRCVNTL---GSYKCACDPGYELAADKKM---------------- 615
Query: 412 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD--- 468
C ACGG I G I SPG+P Y N C W + AP R+ L FE L +D
Sbjct: 616 CEVACGGFITKLN-GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCK 674
Query: 469 -DRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYE-- 525
D + +R+G + +A ++ + P E + S + VE +D++ + G +
Sbjct: 675 YDFVEVRSGLSPDAK-LHGRFCGSETP-EVITSQSNNMRVEFKSDNTVSKRGFRAHFFSD 732
Query: 526 ----AFQQGHCYEPFVK-YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDP 580
A G C V +G++ C GY L + HD
Sbjct: 733 KDECAKDNGGCQHECVNTFGSYLCR-------------CRNGYWLHENG--------HDC 771
Query: 581 QWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRI 640
+ A C+ +I+ G + SPNWP+ Y ++C W + R+ L I
Sbjct: 772 K--------EAGCAHKISSVEGTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEI 823
Query: 641 GPG-----DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQ 694
D L YDG D A +LG++ G + S + + ++F SD G+Q
Sbjct: 824 EQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQ 882
Score = 87.0 bits (214), Expect = 8e-17
Identities = 76/300 (25%), Positives = 122/300 (40%), Gaps = 42/300 (14%)
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----D 469
A CGG + N G+I SP +P +Y + C W + EG + L F+ + D D
Sbjct: 462 ATCGGDM-NKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYD 520
Query: 470 RLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
L +R+G E+ + + Y E + SS +++ +D S AG A + +
Sbjct: 521 YLEVRDGPTEESALI--GHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFK-EV 577
Query: 530 GHCYEPFVKYGNFSSSTPTYPVGTTVEF--SCDPGYTLEQGSIIIECVDPHDPQWNETEP 587
C P +G V T + +CDPGY L +
Sbjct: 578 DECSWP--DHGGCEHRC----VNTLGSYKCACDPGYELAAD-----------------KK 614
Query: 588 ACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLT 647
C C G IT G + SP WP+ Y ++C+W V RI L V + DV
Sbjct: 615 MCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCK 674
Query: 648 F-----YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
+ G A++ G++ G + + + ++ ++F+SD S ++GF HFF
Sbjct: 675 YDFVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVS----KRGFRAHFF 730
Score = 50.8 bits (120), Expect = 6e-06
Identities = 44/176 (25%), Positives = 74/176 (42%), Gaps = 27/176 (15%)
Query: 588 ACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIG-----P 642
A A C G++ AG + SPN+P+ Y ++C+W + V E + L + I
Sbjct: 459 AYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCA 518
Query: 643 GDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
D L DG + ++G + G + +S + ++F SD + + GF +FF
Sbjct: 519 YDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSIN----KAGFAANFF 574
Query: 703 EVPRNDTCPELPEIPNGWKSPSQPELVH---GTVVTYQCY--PGYQVVGSSVLMCQ 753
+ D C W P H T+ +Y+C PGY++ MC+
Sbjct: 575 K--EVDEC--------SW--PDHGGCEHRCVNTLGSYKCACDPGYELAADK-KMCE 617
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/116 (28%), Positives = 58/116 (50%), Gaps = 7/116 (6%)
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DR 470
ACG +++ TTG +PGFP Y + C W + G+++ L+F + L + D
Sbjct: 350 ACGETLQD-TTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDY 408
Query: 471 LIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEA 526
+ +R+G +A P+ + + +P E L+S+ +VE + S+ G YEA
Sbjct: 409 VEVRDGYWRKA-PLLGRFCGDKIP-EPLVSTDSRLWVEFRSSSNILGKGFFAAYEA 462
Score = 37.4 bits (85), Expect = 0.071
Identities = 32/140 (22%), Positives = 65/140 (46%), Gaps = 13/140 (9%)
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML-----DIRVLRIGPGDVLT 647
C + D+ G +P +P Y C+W + V ++I+L D+ R+ D +
Sbjct: 351 CGETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVE 410
Query: 648 FYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
DG A +LG++ G + L ++ + + ++F+S +++LG +GF +
Sbjct: 411 VRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRS--SSNILG--KGFFAAYEATCGG 466
Query: 708 DTCPELPEIPNGWKSPSQPE 727
D + +I +SP+ P+
Sbjct: 467 DMNKDAGQI----QSPNYPD 482
Score = 34.3 bits (77), Expect = 0.60
Identities = 31/118 (26%), Positives = 47/118 (39%), Gaps = 13/118 (11%)
Query: 416 CGGVIR-NATTGRIVSPGFPG--NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
CGG ++ T + S G NY + C W++ A +G + L F + E+ D
Sbjct: 889 CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEEEAD--- 945
Query: 473 IRNGDNVEAPPVYDSYEVEY------LPIEGLLSSGKHFFVELSTDSSGAAAGMALRY 524
D +EA YDS P+E + S+G + TD + G RY
Sbjct: 946 -CGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHARY 1002
>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
sapiens]
Length = 380
Score = 88.6 bits (218), Expect = 3e-17
Identities = 96/366 (26%), Positives = 149/366 (40%), Gaps = 46/366 (12%)
Query: 422 NATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAE----DDDRLIIRNGD 477
N G+I SPG+P +Y ++ W + P+G R+ L+F +L + D + + D
Sbjct: 25 NNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETED 84
Query: 478 NVEAPPV-YDSYEVEYLP-IEGLLSSGKHFFVELSTDSSGAA--AGMALRYEAFQQGHCY 533
V A ++ + E P E +LS G + +D S G Y A C
Sbjct: 85 QVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECK 144
Query: 534 EPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVC 593
E + + Y G SC GY L N T CR C
Sbjct: 145 EREDEELSCDHYCHNYIGGYYC--SCRFGYILHTD--------------NRT---CRVEC 185
Query: 594 SGEI-TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIML---DIRVLRIGPGDVLTFY 649
S + T GV+ SP++P PY + +C++ + +EE + L DI + P +V Y
Sbjct: 186 SDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHP-EVPCPY 244
Query: 650 DGDDLTA--RVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRN 707
D + +VLG + G ++ + T V I F SD G++ +
Sbjct: 245 DYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRA------AG 298
Query: 708 DTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLM------CQWDLTWSED 761
+ CPEL +G PSQ + V C GY+V+ +V M C D TWS
Sbjct: 299 NECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNK 358
Query: 762 LPSCQR 767
+P+C++
Sbjct: 359 IPTCKK 364
Score = 55.1 bits (131), Expect = 3e-07
Identities = 53/197 (26%), Positives = 75/197 (38%), Gaps = 32/197 (16%)
Query: 412 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
C C + TG I SP FP Y + C + +E EG ++L FE + E
Sbjct: 181 CRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIE----- 235
Query: 472 IIRNGDNVEAPPVYDSYEVEYLP-----------IEGLLSSGKHFFVELSTDSSGAAAGM 520
D+ E P YD +++ P E + + + +D+SG G
Sbjct: 236 -----DHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGW 290
Query: 521 ALRYEAFQQGHCYE--PFVKYGNFSSSTPTYPVGTTVEFSCDPGY-----TLEQGSIIIE 573
L Y A C E P V +G S Y V SCD GY +E + IE
Sbjct: 291 RLSYRA-AGNECPELQPPV-HGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIE 348
Query: 574 CVDPHDPQWNETEPACR 590
C+ D W+ P C+
Sbjct: 349 CL--KDGTWSNKIPTCK 363
>gi|4502495 complement component 1, s subcomponent precursor [Homo
sapiens]
Length = 688
Score = 87.4 bits (215), Expect = 6e-17
Identities = 107/450 (23%), Positives = 178/450 (39%), Gaps = 92/450 (20%)
Query: 426 GRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNVEA 481
G I+SP +P Y + + W +E PEG +HL+F + + + D + I +GD E
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
Query: 482 ------------PPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
P+ + ++V Y ++ + S + G A Y A
Sbjct: 81 RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKS--------DFSNEERFTGFAAYYVATDI 132
Query: 530 GHCYEPF-VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPA 588
C + V +F ++ +G SC P Y L HD N
Sbjct: 133 NECTDFVDVPCSHFCNNF----IGGYF-CSCPPEYFL------------HDDMKN----- 170
Query: 589 CRAVCSGEI-TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG---- 643
C CSG++ T G + SPN+P+PY C + + +E+ ++++ +R
Sbjct: 171 CGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADS 230
Query: 644 -----DVLTFYDGDDLTARVLGQYSGP--RSHFKLFTSMADVTIQFQSDPGTSVLGYQQG 696
D L F GD R G Y G + T + I FQ+D + G ++G
Sbjct: 231 AGNCLDSLVFVAGD----RQFGPYCGHGFPGPLNIETKSNALDIIFQTD----LTGQKKG 282
Query: 697 FVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSV------L 750
+ + + P CP+ + PN P++ + V VV C G++VV V
Sbjct: 283 WKLRYHGDPM--PCPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYS 339
Query: 751 MCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPV-GATVQYICDQGFVLM--- 806
CQ + WS CQ V C P +E+ + + P+ + G+ ++Y C++ + M
Sbjct: 340 TCQSNGKWSNSKLKCQPV-DCGIPESIENGK--VEDPESTLFGSVIRYTCEEPYYYMENG 396
Query: 807 GSSILTCHDRQAGSPKWSDRA-----PKCL 831
G C AG+ W + PKC+
Sbjct: 397 GGGEYHC----AGNGSWVNEVLGPELPKCV 422
Score = 34.3 bits (77), Expect = 0.60
Identities = 37/195 (18%), Positives = 71/195 (36%), Gaps = 16/195 (8%)
Query: 412 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
C C G + A G I SP +P Y N C + + +G ++ + + ED D
Sbjct: 171 CGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRR----EDFDVE 226
Query: 472 IIRNGDNVEAPPVYDSYEVEYLPIEG--------LLSSGKHFFVELSTDSSGAAAGMALR 523
+ N V+ + + ++ P G + + + TD +G G LR
Sbjct: 227 AADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLR 286
Query: 524 YEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSI---IIECVDPHDP 580
Y C + + + Y V+ +C G+ + +G + +
Sbjct: 287 YHG-DPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNG 345
Query: 581 QWNETEPACRAVCSG 595
+W+ ++ C+ V G
Sbjct: 346 KWSNSKLKCQPVDCG 360
>gi|41393602 complement component 1, s subcomponent precursor [Homo
sapiens]
Length = 688
Score = 87.4 bits (215), Expect = 6e-17
Identities = 107/450 (23%), Positives = 178/450 (39%), Gaps = 92/450 (20%)
Query: 426 GRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DRLIIRNGDNVEA 481
G I+SP +P Y + + W +E PEG +HL+F + + + D + I +GD E
Sbjct: 21 GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
Query: 482 ------------PPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
P+ + ++V Y ++ + S + G A Y A
Sbjct: 81 RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKS--------DFSNEERFTGFAAYYVATDI 132
Query: 530 GHCYEPF-VKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPA 588
C + V +F ++ +G SC P Y L HD N
Sbjct: 133 NECTDFVDVPCSHFCNNF----IGGYF-CSCPPEYFL------------HDDMKN----- 170
Query: 589 CRAVCSGEI-TDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG---- 643
C CSG++ T G + SPN+P+PY C + + +E+ ++++ +R
Sbjct: 171 CGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADS 230
Query: 644 -----DVLTFYDGDDLTARVLGQYSGP--RSHFKLFTSMADVTIQFQSDPGTSVLGYQQG 696
D L F GD R G Y G + T + I FQ+D + G ++G
Sbjct: 231 AGNCLDSLVFVAGD----RQFGPYCGHGFPGPLNIETKSNALDIIFQTD----LTGQKKG 282
Query: 697 FVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSV------L 750
+ + + P CP+ + PN P++ + V VV C G++VV V
Sbjct: 283 WKLRYHGDPM--PCPK-EDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYS 339
Query: 751 MCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPV-GATVQYICDQGFVLM--- 806
CQ + WS CQ V C P +E+ + + P+ + G+ ++Y C++ + M
Sbjct: 340 TCQSNGKWSNSKLKCQPV-DCGIPESIENGK--VEDPESTLFGSVIRYTCEEPYYYMENG 396
Query: 807 GSSILTCHDRQAGSPKWSDRA-----PKCL 831
G C AG+ W + PKC+
Sbjct: 397 GGGEYHC----AGNGSWVNEVLGPELPKCV 422
Score = 34.3 bits (77), Expect = 0.60
Identities = 37/195 (18%), Positives = 71/195 (36%), Gaps = 16/195 (8%)
Query: 412 CIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRL 471
C C G + A G I SP +P Y N C + + +G ++ + + ED D
Sbjct: 171 CGVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRR----EDFDVE 226
Query: 472 IIRNGDNVEAPPVYDSYEVEYLPIEG--------LLSSGKHFFVELSTDSSGAAAGMALR 523
+ N V+ + + ++ P G + + + TD +G G LR
Sbjct: 227 AADSAGNCLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLR 286
Query: 524 YEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSI---IIECVDPHDP 580
Y C + + + Y V+ +C G+ + +G + +
Sbjct: 287 YHG-DPMPCPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNG 345
Query: 581 QWNETEPACRAVCSG 595
+W+ ++ C+ V G
Sbjct: 346 KWSNSKLKCQPVDCG 360
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 87.0 bits (214), Expect = 8e-17
Identities = 108/477 (22%), Positives = 183/477 (38%), Gaps = 84/477 (17%)
Query: 244 CSWNFSGPEGSLDSPT--DLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVE 301
C + G + SP D P+ V C + I V G+ V + Q+ + ++ +
Sbjct: 435 CGGDVKKDYGHIQSPNYPDDYRPSKV---CIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 302 GLGGPDPLPLANQSFLLRGQV--------IRSPTHQAALRFQSLPPPAGPGTFHFHYQAY 353
L D ++S L G+ I+S + + L+F S F ++
Sbjct: 492 YLEVRDG---HSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVS-DGSINKAGFAVNFFKE 547
Query: 354 LLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCI 413
+ C P R G L+ GS + C GY+L + C
Sbjct: 548 VDECSRPNR---GGCEQRCLNTLGSYKCSCDPGYELAPDKRR----------------CE 588
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----D 469
AACGG + G I SPG+P Y N C W L AP R+ L F+ +D D
Sbjct: 589 AACGGFLTKLN-GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYD 647
Query: 470 RLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQ 529
+ +R+G ++ ++ + P E + S + VE +D++ + G + + +
Sbjct: 648 FVEVRSGLTADSK-LHGKFCGSEKP-EVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKD 705
Query: 530 ------GHCYEPFVK-YGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQW 582
G C + V +G++ E C G+ L HD +
Sbjct: 706 ECSKDNGGCQQDCVNTFGSY-------------ECQCRSGFVLHDNK--------HDCK- 743
Query: 583 NETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGP 642
A C ++T ++G + SPNWP+ Y ++C W + R+ L + I
Sbjct: 744 -------EAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIES 796
Query: 643 G-----DVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQ 694
D L +DG D A VLG++ G + + + + + ++F SD G+Q
Sbjct: 797 QPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQ 853
Score = 80.5 bits (197), Expect = 7e-15
Identities = 70/300 (23%), Positives = 119/300 (39%), Gaps = 42/300 (14%)
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----D 469
A CGG ++ G I SP +P +Y + C W ++ EG + L F+ + D D
Sbjct: 433 AICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 470 RLIIRNGDNVEAPPV--YDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAF 527
L +R+G + + + Y YE + + S+ +++ +D S AG A+ +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKP----DDIKSTSSRLWLKFVSDGSINKAGFAVNFFK- 546
Query: 528 QQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEP 587
+ C P + + SCDPGY L +
Sbjct: 547 EVDECSRP----NRGGCEQRCLNTLGSYKCSCDPGYELAPD-----------------KR 585
Query: 588 ACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLT 647
C A C G +T G + SP WP+ Y ++CIW + RI L DV
Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
Query: 648 F-----YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
+ G +++ G++ G + + ++ ++F+SD S ++GF HFF
Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVS----KKGFKAHFF 701
Score = 47.8 bits (112), Expect = 5e-05
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 12/140 (8%)
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DR 470
ACG ++++T G SP +P YS ++ C W + G+++ L+F + L D
Sbjct: 321 ACGETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDY 379
Query: 471 LIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
+ +R+G +A P+ + LP E ++S+ +VE + S+ G YEA G
Sbjct: 380 VEVRDGFWRKA-PLRGRFCGSKLP-EPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
Query: 531 HCYEPFVKYGNFSSSTPTYP 550
+ YG+ S P YP
Sbjct: 438 DVKK---DYGHIQS--PNYP 452
Score = 37.4 bits (85), Expect = 0.071
Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 9/102 (8%)
Query: 613 YGRGQDCIWGVHVEEDKRIMLDIRVLRIGPG-----DVLTFYDGDDLTARVLGQYSGPRS 667
Y G DC W + EE + L + + D + +DG D TA LG+Y G
Sbjct: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943
Query: 668 HFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDT 709
+++++ V ++F SD + ++GF + + DT
Sbjct: 944 PEEVYSAGDSVLVKFHSDDTIT----KKGFHLRYTSTKFQDT 981
Score = 37.0 bits (84), Expect = 0.092
Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVL-----RIGPGDVLT 647
C + DS G SP +P Y C+W + V ++I+L+ L R+ D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 648 FYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQS 684
DG A + G++ G + + ++ + + ++F+S
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRS 418
Score = 35.4 bits (80), Expect = 0.27
Identities = 33/118 (27%), Positives = 49/118 (41%), Gaps = 13/118 (11%)
Query: 416 CGGVIR-NATTGRIVSPGFPG--NYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLI 472
CGG +R + T + S G NY + C W++ A EG + L F+ + E+ D
Sbjct: 860 CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETD--- 916
Query: 473 IRNGDNVEAPPVYDSYEVEY------LPIEGLLSSGKHFFVELSTDSSGAAAGMALRY 524
D +E YDS P E + S+G V+ +D + G LRY
Sbjct: 917 -CGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
>gi|168693643 decay accelerating factor for complement isoform 2
precursor [Homo sapiens]
Length = 440
Score = 85.1 bits (209), Expect = 3e-16
Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 18/202 (8%)
Query: 710 CPELPEIPNGWKSPS--QPELVH-----GTVVTYQCYPGYQVVGS--SVLMCQWDLTWSE 760
C E+P S S QP + GTVV Y+C PGY+ S L C +L WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPK-FPVGATVQYICDQGFVLMGSSILTCHDRQAG 819
+ C++ SC +PG++ + + I P GAT+ + C+ G+ L GS+ C
Sbjct: 154 AVEFCKK-KSCPNPGEIRNGQ--IDVPGGILFGATISFSCNTGYKLFGSTSSFCLI-SGS 209
Query: 820 SPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIK 879
S +WSD P+C + C +NG E+ + ++ ++C G+ + G+ SI
Sbjct: 210 SVQWSDPLPEC---REIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIY 266
Query: 880 C-VPGHPSHWSDPPPICRAASL 900
C V WS PPP CR SL
Sbjct: 267 CTVNNDEGEWSGPPPECRGKSL 288
Score = 62.8 bits (151), Expect = 2e-09
Identities = 59/196 (30%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 710 CPELPEIPNGWKS-PSQPELVHGTVVTYQCYPGYQVVGSSV--LMCQWDLTWSEDLPSCQ 766
C P++PN + + TV+TY+C + + ++C WS+ C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 767 RVTSCHDPGDVEHS---RRLISSPKFPVGATVQYICDQGFVLMGSSI--LTCHDRQAGSP 821
R SC P + + + I+ FPVG V+Y C G+ S LTC
Sbjct: 96 R--SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL---- 149
Query: 822 KWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC- 880
KWS C + K C NG + GATI FSC GY L G S C
Sbjct: 150 KWSTAVEFC---KKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCL 205
Query: 881 VPGHPSHWSDPPPICR 896
+ G WSDP P CR
Sbjct: 206 ISGSSVQWSDPLPECR 221
Score = 33.1 bits (74), Expect = 1.3
Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 12/100 (12%)
Query: 679 TIQFQSDPGTSVLGYQQGF-VIHFFEVPRNDT--------CPELPEIPNGWKSPSQPELV 729
TI F + G + G F +I V +D CP P+I NG +
Sbjct: 185 TISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYG 244
Query: 730 HGTVVTYQCYPGYQVVGSSVLMC---QWDLTWSEDLPSCQ 766
+ VTY C G+ ++G + C + WS P C+
Sbjct: 245 YRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 32.3 bits (72), Expect = 2.3
Identities = 32/135 (23%), Positives = 48/135 (35%), Gaps = 14/135 (10%)
Query: 771 CHDPGDVEHSRRLISS-PKFPVGATVQYICDQGFVLMGS---SILTCHDRQAGSPKWSDR 826
C P DV +++ + FP + Y C++ FV + S++ Q WSD
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ-----WSDI 90
Query: 827 APKCLLEQLKPCHGLSAPENGARSP--EKQLHPAGATIHFSCAPGYVLKGQASIKCVPGH 884
C P SA + P + P G + + C PGY + S K
Sbjct: 91 EEFCNRSCEVPTRLNSA---SLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQ 147
Query: 885 PSHWSDPPPICRAAS 899
WS C+ S
Sbjct: 148 NLKWSTAVEFCKKKS 162
Score = 32.0 bits (71), Expect = 3.0
Identities = 13/41 (31%), Positives = 20/41 (48%)
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
G T+ FSC+ GY L + + QW++ P CR +
Sbjct: 183 GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREI 223
>gi|10835143 decay accelerating factor for complement isoform 1
preproprotein [Homo sapiens]
Length = 381
Score = 85.1 bits (209), Expect = 3e-16
Identities = 64/202 (31%), Positives = 95/202 (47%), Gaps = 18/202 (8%)
Query: 710 CPELPEIPNGWKSPS--QPELVH-----GTVVTYQCYPGYQVVGS--SVLMCQWDLTWSE 760
C E+P S S QP + GTVV Y+C PGY+ S L C +L WS
Sbjct: 94 CNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWST 153
Query: 761 DLPSCQRVTSCHDPGDVEHSRRLISSPK-FPVGATVQYICDQGFVLMGSSILTCHDRQAG 819
+ C++ SC +PG++ + + I P GAT+ + C+ G+ L GS+ C
Sbjct: 154 AVEFCKK-KSCPNPGEIRNGQ--IDVPGGILFGATISFSCNTGYKLFGSTSSFCLI-SGS 209
Query: 820 SPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIK 879
S +WSD P+C + C +NG E+ + ++ ++C G+ + G+ SI
Sbjct: 210 SVQWSDPLPEC---REIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIY 266
Query: 880 C-VPGHPSHWSDPPPICRAASL 900
C V WS PPP CR SL
Sbjct: 267 CTVNNDEGEWSGPPPECRGKSL 288
Score = 62.8 bits (151), Expect = 2e-09
Identities = 59/196 (30%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 710 CPELPEIPNGWKS-PSQPELVHGTVVTYQCYPGYQVVGSSV--LMCQWDLTWSEDLPSCQ 766
C P++PN + + TV+TY+C + + ++C WS+ C
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCN 95
Query: 767 RVTSCHDPGDVEHS---RRLISSPKFPVGATVQYICDQGFVLMGSSI--LTCHDRQAGSP 821
R SC P + + + I+ FPVG V+Y C G+ S LTC
Sbjct: 96 R--SCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNL---- 149
Query: 822 KWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKC- 880
KWS C + K C NG + GATI FSC GY L G S C
Sbjct: 150 KWSTAVEFC---KKKSCPNPGEIRNGQIDVPGGIL-FGATISFSCNTGYKLFGSTSSFCL 205
Query: 881 VPGHPSHWSDPPPICR 896
+ G WSDP P CR
Sbjct: 206 ISGSSVQWSDPLPECR 221
Score = 33.1 bits (74), Expect = 1.3
Identities = 26/100 (26%), Positives = 39/100 (39%), Gaps = 12/100 (12%)
Query: 679 TIQFQSDPGTSVLGYQQGF-VIHFFEVPRNDT--------CPELPEIPNGWKSPSQPELV 729
TI F + G + G F +I V +D CP P+I NG +
Sbjct: 185 TISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYG 244
Query: 730 HGTVVTYQCYPGYQVVGSSVLMC---QWDLTWSEDLPSCQ 766
+ VTY C G+ ++G + C + WS P C+
Sbjct: 245 YRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECR 284
Score = 32.3 bits (72), Expect = 2.3
Identities = 32/135 (23%), Positives = 48/135 (35%), Gaps = 14/135 (10%)
Query: 771 CHDPGDVEHSRRLISS-PKFPVGATVQYICDQGFVLMGS---SILTCHDRQAGSPKWSDR 826
C P DV +++ + FP + Y C++ FV + S++ Q WSD
Sbjct: 36 CGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQ-----WSDI 90
Query: 827 APKCLLEQLKPCHGLSAPENGARSP--EKQLHPAGATIHFSCAPGYVLKGQASIKCVPGH 884
C P SA + P + P G + + C PGY + S K
Sbjct: 91 EEFCNRSCEVPTRLNSA---SLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQ 147
Query: 885 PSHWSDPPPICRAAS 899
WS C+ S
Sbjct: 148 NLKWSTAVEFCKKKS 162
Score = 32.0 bits (71), Expect = 3.0
Identities = 13/41 (31%), Positives = 20/41 (48%)
Query: 552 GTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAV 592
G T+ FSC+ GY L + + QW++ P CR +
Sbjct: 183 GATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREI 223
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 82.0 bits (201), Expect = 2e-15
Identities = 71/302 (23%), Positives = 120/302 (39%), Gaps = 42/302 (13%)
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----D 469
A CGG ++ G I SP +P +Y + C W ++ EG + L F+ + D D
Sbjct: 433 AICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 470 RLIIRNGDNVEAPPV--YDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAF 527
L +R+G + + + Y YE + + S+ +++ +D S AG A+ +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKP----DDIKSTSSRLWLKFVSDGSINKAGFAVNFFK- 546
Query: 528 QQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEP 587
+ C P + + SCDPGY L +
Sbjct: 547 EVDECSRP----NRGGCEQRCLNTLGSYKCSCDPGYELAPD-----------------KR 585
Query: 588 ACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLT 647
C A C G +T G + SP WP+ Y ++CIW + RI L DV
Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
Query: 648 F-----YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
+ G +++ G++ G + + ++ ++F+SD S ++GF HFF
Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVS----KKGFKAHFF 701
Query: 703 EV 704
V
Sbjct: 702 SV 703
Score = 47.8 bits (112), Expect = 5e-05
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 12/140 (8%)
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DR 470
ACG ++++T G SP +P YS ++ C W + G+++ L+F + L D
Sbjct: 321 ACGETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDY 379
Query: 471 LIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
+ +R+G +A P+ + LP E ++S+ +VE + S+ G YEA G
Sbjct: 380 VEVRDGFWRKA-PLRGRFCGSKLP-EPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
Query: 531 HCYEPFVKYGNFSSSTPTYP 550
+ YG+ S P YP
Sbjct: 438 DVKK---DYGHIQS--PNYP 452
Score = 37.0 bits (84), Expect = 0.092
Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVL-----RIGPGDVLT 647
C + DS G SP +P Y C+W + V ++I+L+ L R+ D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 648 FYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQS 684
DG A + G++ G + + ++ + + ++F+S
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRS 418
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 81.3 bits (199), Expect = 4e-15
Identities = 71/304 (23%), Positives = 120/304 (39%), Gaps = 42/304 (13%)
Query: 414 AACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----D 469
A CGG ++ G I SP +P +Y + C W ++ EG + L F+ + D D
Sbjct: 433 AICGGDVKK-DYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYD 491
Query: 470 RLIIRNGDNVEAPPV--YDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAF 527
L +R+G + + + Y YE + + S+ +++ +D S AG A+ +
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKP----DDIKSTSSRLWLKFVSDGSINKAGFAVNFFK- 546
Query: 528 QQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEP 587
+ C P + + SCDPGY L +
Sbjct: 547 EVDECSRP----NRGGCEQRCLNTLGSYKCSCDPGYELAPD-----------------KR 585
Query: 588 ACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLT 647
C A C G +T G + SP WP+ Y ++CIW + RI L DV
Sbjct: 586 RCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCK 645
Query: 648 F-----YDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFF 702
+ G +++ G++ G + + ++ ++F+SD S ++GF HFF
Sbjct: 646 YDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVS----KKGFKAHFF 701
Query: 703 EVPR 706
R
Sbjct: 702 SEKR 705
Score = 47.8 bits (112), Expect = 5e-05
Identities = 39/140 (27%), Positives = 66/140 (47%), Gaps = 12/140 (8%)
Query: 415 ACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDD----DR 470
ACG ++++T G SP +P YS ++ C W + G+++ L+F + L D
Sbjct: 321 ACGETLQDST-GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDY 379
Query: 471 LIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQG 530
+ +R+G +A P+ + LP E ++S+ +VE + S+ G YEA G
Sbjct: 380 VEVRDGFWRKA-PLRGRFCGSKLP-EPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
Query: 531 HCYEPFVKYGNFSSSTPTYP 550
+ YG+ S P YP
Sbjct: 438 DVKK---DYGHIQS--PNYP 452
Score = 37.0 bits (84), Expect = 0.092
Identities = 23/97 (23%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 593 CSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVL-----RIGPGDVLT 647
C + DS G SP +P Y C+W + V ++I+L+ L R+ D +
Sbjct: 322 CGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVE 381
Query: 648 FYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQS 684
DG A + G++ G + + ++ + + ++F+S
Sbjct: 382 VRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRS 418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,115,073
Number of Sequences: 37866
Number of extensions: 2895839
Number of successful extensions: 18124
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 175
Number of HSP's successfully gapped in prelim test: 699
Number of HSP's that attempted gapping in prelim test: 10695
Number of HSP's gapped (non-prelim): 4745
length of query: 994
length of database: 18,247,518
effective HSP length: 112
effective length of query: 882
effective length of database: 14,006,526
effective search space: 12353755932
effective search space used: 12353755932
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.