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Search of human proteins with 148233402
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
(283 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 580 e-166
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 580 e-166
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 322 2e-88
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 322 2e-88
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 322 2e-88
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 322 2e-88
gi|42558283 gap junction protein beta 2 [Homo sapiens] 322 2e-88
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 262 2e-70
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 254 5e-68
gi|54607056 connexin 31 [Homo sapiens] 249 1e-66
gi|13128960 connexin 31 [Homo sapiens] 249 1e-66
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 232 3e-61
gi|55953076 connexin 50 [Homo sapiens] 218 5e-57
gi|22779877 connexin 46 [Homo sapiens] 215 4e-56
gi|4504001 connexin 43 [Homo sapiens] 207 6e-54
gi|62865885 connexin 37 [Homo sapiens] 206 2e-53
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 204 7e-53
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 192 2e-49
gi|32483412 connexin 40 [Homo sapiens] 190 1e-48
gi|6631083 connexin 40 [Homo sapiens] 190 1e-48
gi|122939172 connexin 45 [Homo sapiens] 171 9e-43
gi|69122473 connexin 45 [Homo sapiens] 171 9e-43
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 154 8e-38
gi|145699105 connexin40.1 [Homo sapiens] 142 3e-34
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 126 2e-29
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 114 1e-25
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 113 2e-25
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 86 5e-17
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 86 5e-17
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 86 5e-17
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 580 bits (1495), Expect = e-166
Identities = 283/283 (100%), Positives = 283/283 (100%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC
Sbjct: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV 120
NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV
Sbjct: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV 120
Query: 121 KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF
Sbjct: 121 KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
Query: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS 240
VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS
Sbjct: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS 240
Query: 241 PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC 283
PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC
Sbjct: 241 PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC 283
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 580 bits (1495), Expect = e-166
Identities = 283/283 (100%), Positives = 283/283 (100%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC
Sbjct: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV 120
NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV
Sbjct: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV 120
Query: 121 KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF
Sbjct: 121 KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
Query: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS 240
VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS
Sbjct: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS 240
Query: 241 PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC 283
PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC
Sbjct: 241 PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCSAC 283
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 322 bits (826), Expect = 2e-88
Identities = 148/255 (58%), Positives = 197/255 (77%), Gaps = 6/255 (2%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W L+T + GVN+HST+IG+VW++VIFIFR+M+LVVAA+ VWGDE+ F+CNTLQPGC
Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQH-IEKKMLRLEGHGDPLHLEE 119
+VCYD FFP+SH+RLW+LQLI VSTPALLVAMHVA+ +H +K R E D +E+
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
Query: 120 VKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDC 179
+K+ KV I G+LWWTY S+ FR++FEA FMYVFY LY GY + ++KC + PCPN VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
Query: 180 FVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRL 239
F+SRPTEKTVFT+FM++AS IC++LNVAE+ YL+++ C RR++R + H L
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHP----NHAL 236
Query: 240 SPEYKQNEINKLLSE 254
E KQNE+N+L+S+
Sbjct: 237 K-ESKQNEMNELISD 250
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 322 bits (826), Expect = 2e-88
Identities = 148/255 (58%), Positives = 197/255 (77%), Gaps = 6/255 (2%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W L+T + GVN+HST+IG+VW++VIFIFR+M+LVVAA+ VWGDE+ F+CNTLQPGC
Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQH-IEKKMLRLEGHGDPLHLEE 119
+VCYD FFP+SH+RLW+LQLI VSTPALLVAMHVA+ +H +K R E D +E+
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
Query: 120 VKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDC 179
+K+ KV I G+LWWTY S+ FR++FEA FMYVFY LY GY + ++KC + PCPN VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
Query: 180 FVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRL 239
F+SRPTEKTVFT+FM++AS IC++LNVAE+ YL+++ C RR++R + H L
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHP----NHAL 236
Query: 240 SPEYKQNEINKLLSE 254
E KQNE+N+L+S+
Sbjct: 237 K-ESKQNEMNELISD 250
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 322 bits (826), Expect = 2e-88
Identities = 148/255 (58%), Positives = 197/255 (77%), Gaps = 6/255 (2%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W L+T + GVN+HST+IG+VW++VIFIFR+M+LVVAA+ VWGDE+ F+CNTLQPGC
Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQH-IEKKMLRLEGHGDPLHLEE 119
+VCYD FFP+SH+RLW+LQLI VSTPALLVAMHVA+ +H +K R E D +E+
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
Query: 120 VKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDC 179
+K+ KV I G+LWWTY S+ FR++FEA FMYVFY LY GY + ++KC + PCPN VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
Query: 180 FVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRL 239
F+SRPTEKTVFT+FM++AS IC++LNVAE+ YL+++ C RR++R + H L
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHP----NHAL 236
Query: 240 SPEYKQNEINKLLSE 254
E KQNE+N+L+S+
Sbjct: 237 K-ESKQNEMNELISD 250
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 322 bits (826), Expect = 2e-88
Identities = 148/255 (58%), Positives = 197/255 (77%), Gaps = 6/255 (2%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W L+T + GVN+HST+IG+VW++VIFIFR+M+LVVAA+ VWGDE+ F+CNTLQPGC
Sbjct: 1 MDWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQH-IEKKMLRLEGHGDPLHLEE 119
+VCYD FFP+SH+RLW+LQLI VSTPALLVAMHVA+ +H +K R E D +E+
Sbjct: 61 KNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKRNDFKDIED 120
Query: 120 VKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDC 179
+K+ KV I G+LWWTY S+ FR++FEA FMYVFY LY GY + ++KC + PCPN VDC
Sbjct: 121 IKKQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDC 180
Query: 180 FVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRL 239
F+SRPTEKTVFT+FM++AS IC++LNVAE+ YL+++ C RR++R + H L
Sbjct: 181 FISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRRSKRAQTQKNHP----NHAL 236
Query: 240 SPEYKQNEINKLLSE 254
E KQNE+N+L+S+
Sbjct: 237 K-ESKQNEMNELISD 250
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 322 bits (826), Expect = 2e-88
Identities = 144/224 (64%), Positives = 189/224 (84%), Gaps = 1/224 (0%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W L T+L GVN+HST+IG++WL+V+FIFRIM+LVVAA+ VWGDE++ F+CNTLQPGC
Sbjct: 1 MDWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEK-KMLRLEGHGDPLHLEE 119
+VCYD +FPISH+RLW+LQLI VSTPALLVAMHVA+++H +K K ++ E + +EE
Sbjct: 61 KNVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYRRHEKKRKFIKGEIKSEFKDIEE 120
Query: 120 VKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDC 179
+K KV I G+LWWTY S+ FR++FEA FMYVFY++Y G++M RLVKC+ +PCPNTVDC
Sbjct: 121 IKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDC 180
Query: 180 FVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQR 223
FVSRPTEKTVFTVFM+A SGICI+LNV E+ YL+IR C+ ++++
Sbjct: 181 FVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIRYCSGKSKK 224
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 262 bits (670), Expect = 2e-70
Identities = 118/217 (54%), Positives = 161/217 (74%), Gaps = 4/217 (1%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
MNW L LLSGVN++ST + R+WLSV+FIFR++V VVAAE VW DE+ F+CNT QPGC
Sbjct: 1 MNWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV 120
+VCYD+FFP+SHVRLW+LQLILV+ P+LLV MHVA+++ E+K G P + +
Sbjct: 61 PNVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNL 120
Query: 121 KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
+ + G LWWTY++S++F+ +A F+Y+F+ LY Y M R+V C V PCP+TVDC+
Sbjct: 121 SKKR----GGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCY 176
Query: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRAC 217
+SRPTEK VFT FM+ + ICI+LN++EV YL+ + C
Sbjct: 177 ISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRC 213
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 254 bits (650), Expect = 5e-68
Identities = 120/230 (52%), Positives = 166/230 (72%), Gaps = 15/230 (6%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
MNW+ LLSGVN++STA GR+WLS++FIFR++V +V AE VW D+ F CNT QPGC
Sbjct: 1 MNWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117
++VC+D+FFP+SHVRLW+LQLILV+ P+LLV MHVA+++ EK+ E HG+ L+L
Sbjct: 61 SNVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYREVQEKR--HREAHGENSGRLYL 118
Query: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTV 177
K+ G LWWTYV S+VF+ + F+YVF+ YP Y + +VKC PCPN V
Sbjct: 119 NPGKKR-----GGLWWTYVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIV 173
Query: 178 DCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRAC-----ARRAQ 222
DCF+S+P+EK +FT+FM+A + ICI+LN+ E++YL+ + C AR+AQ
Sbjct: 174 DCFISKPSEKNIFTLFMVATAAICILLNLVELIYLVSKRCHECLAARKAQ 223
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 249 bits (637), Expect = 1e-66
Identities = 116/223 (52%), Positives = 163/223 (73%), Gaps = 11/223 (4%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W L LLSGVN++STA GR+WLSV+F+FR++V VVAAE VWGDE+ F CNT QPGC
Sbjct: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117
+VCYD +FPIS++RLW+LQLI V+ P+LLV +HVA+++ E++ + HGD L+
Sbjct: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERR--HRQKHGDQCAKLYD 118
Query: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKC-DVYPCPNT 176
K+H G LWWTY+ S++F+L+ E +F+Y+ + L+ G+ M RLV+C +V PCPN
Sbjct: 119 NAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173
Query: 177 VDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR 219
VDC+++RPTEK +FT FM+ AS +CI+L + E+ YLI R
Sbjct: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 249 bits (637), Expect = 1e-66
Identities = 116/223 (52%), Positives = 163/223 (73%), Gaps = 11/223 (4%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W L LLSGVN++STA GR+WLSV+F+FR++V VVAAE VWGDE+ F CNT QPGC
Sbjct: 1 MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGD---PLHL 117
+VCYD +FPIS++RLW+LQLI V+ P+LLV +HVA+++ E++ + HGD L+
Sbjct: 61 TNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERR--HRQKHGDQCAKLYD 118
Query: 118 EEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKC-DVYPCPNT 176
K+H G LWWTY+ S++F+L+ E +F+Y+ + L+ G+ M RLV+C +V PCPN
Sbjct: 119 NAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNI 173
Query: 177 VDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR 219
VDC+++RPTEK +FT FM+ AS +CI+L + E+ YLI R
Sbjct: 174 VDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 232 bits (591), Expect = 3e-61
Identities = 105/215 (48%), Positives = 155/215 (72%), Gaps = 11/215 (5%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W L LLSGVN++ST G +WL+V+F+FR++V +VAAE VW DE+ F CN+ QPGC
Sbjct: 1 MSWMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEV 120
+VC+D FFPIS VRLW+LQLI+VSTP+LLV +HVA+ + EK+ H +++
Sbjct: 61 KNVCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYHEGREKR-----------HRKKL 109
Query: 121 KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
+ G LW+ Y+IS++ + FE F+ +FY LY G+++ L+KCD+ PCPNTVDCF
Sbjct: 110 YVSPGTMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVDCF 169
Query: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIR 215
+S+PTEKT+F +F++ S +CI+LN E+ +L+++
Sbjct: 170 ISKPTEKTIFILFLVITSCLCIVLNFIELSFLVLK 204
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 218 bits (555), Expect = 5e-57
Identities = 111/243 (45%), Positives = 152/243 (62%), Gaps = 18/243 (7%)
Query: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
+W+ L +L VN HST IGRVWL+V+FIFRI++L AAE VWGDE+S F+CNT QPGC
Sbjct: 3 DWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCE 62
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEG---------HG 112
+VCYD+ FPISH+RLW LQ+I VSTP+L+ H H +E+K E +G
Sbjct: 63 NVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGTNG 122
Query: 113 DPLHLEEVKR-------HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRL 165
P VK+ K + GTL TY+ ++F+ LFE F+ Y LY G+ ++ L
Sbjct: 123 GP-DQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLY-GFRILPL 180
Query: 166 VKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRS 225
+C +PCPN VDCFVSRPTEKT+F +FML+ + + + LNV E+ +L ++ +R
Sbjct: 181 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV 240
Query: 226 NPP 228
P
Sbjct: 241 EQP 243
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 215 bits (547), Expect = 4e-56
Identities = 108/225 (48%), Positives = 145/225 (64%), Gaps = 16/225 (7%)
Query: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
+W+ L LL HST IG+VWL+V+FIFRI+VL AAE VWGDE+S F CNT QPGC
Sbjct: 3 DWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCE 62
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVK 121
+VCYD+ FPISH+R W+LQ+I VSTP L+ HV H +E+K E + L E
Sbjct: 63 NVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKERE-EEEQLKRESPS 121
Query: 122 --------------RHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVK 167
R +V ++G L TYV +++F+ LFE F+ Y LY G+ + L +
Sbjct: 122 PKEPPQDNPSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLY-GFELKPLYR 180
Query: 168 CDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
CD +PCPNTVDCF+SRPTEKT+F +FMLA + ++LN+ E+ +L
Sbjct: 181 CDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHL 225
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 207 bits (528), Expect = 6e-54
Identities = 105/245 (42%), Positives = 153/245 (62%), Gaps = 20/245 (8%)
Query: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
+W+ L LL V +STA G+VWLSV+FIFRI++L A ES WGDE+S+F CNT QPGC
Sbjct: 3 DWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCE 62
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLE---------GHG 112
+VCYD+ FPISHVR W LQ+I VS P LL HV + E+K+ + E G
Sbjct: 63 NVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDGVN 122
Query: 113 DPLHLEEV----------KRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAM 162
+HL+++ + KV + G L TY+IS++F+ +FE F+ + + +Y G+++
Sbjct: 123 VDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIY-GFSL 181
Query: 163 VRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQ 222
+ C PCP+ VDCF+SRPTEKT+F +FML S + + LN+ E+ Y+ + R +
Sbjct: 182 SAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVK 241
Query: 223 RRSNP 227
+S+P
Sbjct: 242 GKSDP 246
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 206 bits (523), Expect = 2e-53
Identities = 112/253 (44%), Positives = 155/253 (61%), Gaps = 22/253 (8%)
Query: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
+W L LL V HST +G++WL+V+FIFRI++L +A ESVWGDE+S F CNT QPGC
Sbjct: 3 DWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCT 62
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGH------GDP- 114
+VCYDQ FPISH+R W LQ + VSTP L+ HV + E+++ + EG DP
Sbjct: 63 NVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQ 122
Query: 115 --LHLEEVKRH----------KVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAM 162
L V+R ++ I G L TYV SV+ + + EA F+Y + LY G+ M
Sbjct: 123 VERALAAVERQMAKISVAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY-GWTM 181
Query: 163 VRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACAR--R 220
+ C PCP VDCFVSRPTEKT+F +FML I ++LN+ E+V+L+ R +R R
Sbjct: 182 EPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMR 241
Query: 221 AQRRSNPPSRKGS 233
A++ + P +G+
Sbjct: 242 ARQGQDAPPTQGT 254
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 204 bits (519), Expect = 7e-53
Identities = 107/246 (43%), Positives = 152/246 (61%), Gaps = 22/246 (8%)
Query: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
+W L +L V+ HST +G++WL+++FIFR++VL VAAE VW DE+S+F CNT QPGCN
Sbjct: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQ-------QHIEKKMLRLEGHGDP 114
++CYD FPIS +R W LQ+I VS+P+L+ H ++ + +K LR +
Sbjct: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
Query: 115 LHLEEVKR--------------HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGY 160
L LEE +R HKV + G L TYV+ ++ R + E FM Y+LY G+
Sbjct: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
Query: 161 AMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARR 220
M L KC PCPN VDCFVSRPTEKT+F +FM + + I ++LN+ E+ +L IR R
Sbjct: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRT 241
Query: 221 AQRRSN 226
++S+
Sbjct: 242 LYKKSS 247
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 192 bits (489), Expect = 2e-49
Identities = 104/232 (44%), Positives = 142/232 (61%), Gaps = 22/232 (9%)
Query: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
+W L L V+ HST IG++WL+++FIFR++VL VAAE VW DE+S FICNT QPGC
Sbjct: 3 DWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCR 62
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-------EKKMLRLE----- 109
+VCYDQ FPIS +R W LQ+I VS+P+L+ H ++ + K LR+E
Sbjct: 63 NVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVE 122
Query: 110 ---------GHGDPLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGY 160
+ LE+ K +K + GTL TYVI + R + E FM YLLY G+
Sbjct: 123 FEMPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY-GF 181
Query: 161 AMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
+ L KC +PCPN +DCFVSRPTEKT+F +FM + + I + LN+ E+ +L
Sbjct: 182 HLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHL 233
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 190 bits (483), Expect = 1e-48
Identities = 101/228 (44%), Positives = 142/228 (62%), Gaps = 18/228 (7%)
Query: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
+W+ L L V++HST +G+VWL+V+FIFR++VL AAES WGDE++ F C+T+QPGC
Sbjct: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-EKKMLR-------LEGHGD 113
+VCYDQ FPISH+R W LQ+I VSTP+L+ H H + EK+ LR + G G
Sbjct: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
Query: 114 ---------PLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVR 164
L E ++ + GTL TYV S++ R E F+ Y +Y G +
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
Query: 165 LVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
L C PCP+ V+C+VSRPTEK VF VFMLA + + ++L++AE+ +L
Sbjct: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 190 bits (483), Expect = 1e-48
Identities = 101/228 (44%), Positives = 142/228 (62%), Gaps = 18/228 (7%)
Query: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
+W+ L L V++HST +G+VWL+V+FIFR++VL AAES WGDE++ F C+T+QPGC
Sbjct: 3 DWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQ 62
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHI-EKKMLR-------LEGHGD 113
+VCYDQ FPISH+R W LQ+I VSTP+L+ H H + EK+ LR + G G
Sbjct: 63 NVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGSGS 122
Query: 114 ---------PLHLEEVKRHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVR 164
L E ++ + GTL TYV S++ R E F+ Y +Y G +
Sbjct: 123 YEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIY-GIFLTT 181
Query: 165 LVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
L C PCP+ V+C+VSRPTEK VF VFMLA + + ++L++AE+ +L
Sbjct: 182 LHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHL 229
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 171 bits (432), Expect = 9e-43
Identities = 106/333 (31%), Positives = 168/333 (50%), Gaps = 72/333 (21%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W+ L LL ++ HST +G++WL+V+ +FRI++ V ES++ DE+S F+CNT QPGC
Sbjct: 1 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALL---VAMH-VAHQQH--IEKKMLRLEGHG-- 112
+VCYD F P+SHVR W Q+ILV+TP+++ A+H +A +H +KK R + +
Sbjct: 61 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120
Query: 113 ----------------DPLHLEEVK-------------------RHKVHISGTLWWTYVI 137
DP+ E++ R ++ G L YV+
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYVL 179
Query: 138 SVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAA 197
++ R +FE F+ Y LY G+ + C PCP+ +DCF+SRPTEKT+F + M
Sbjct: 180 QLLARTVFEVGFLIGQYFLY-GFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGV 238
Query: 198 SGICIILNVAEVVYL---IIRACARRAQRRSNPPSRKG-----------SGFGHRLSPE- 242
+G+C++LN+ E+++L IR +R P G+ + P+
Sbjct: 239 TGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQ 298
Query: 243 ------------YKQNEINKLLSEQDGSLKDIL 263
YKQN+ N +Q GS ++ L
Sbjct: 299 IQYTELSNAKIAYKQNKANTAQEQQYGSHEENL 331
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 171 bits (432), Expect = 9e-43
Identities = 106/333 (31%), Positives = 168/333 (50%), Gaps = 72/333 (21%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W+ L LL ++ HST +G++WL+V+ +FRI++ V ES++ DE+S F+CNT QPGC
Sbjct: 1 MSWSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGC 60
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALL---VAMH-VAHQQH--IEKKMLRLEGHG-- 112
+VCYD F P+SHVR W Q+ILV+TP+++ A+H +A +H +KK R + +
Sbjct: 61 ENVCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMR 120
Query: 113 ----------------DPLHLEEVK-------------------RHKVHISGTLWWTYVI 137
DP+ E++ R ++ G L YV+
Sbjct: 121 WKQHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYVL 179
Query: 138 SVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAA 197
++ R +FE F+ Y LY G+ + C PCP+ +DCF+SRPTEKT+F + M
Sbjct: 180 QLLARTVFEVGFLIGQYFLY-GFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGV 238
Query: 198 SGICIILNVAEVVYL---IIRACARRAQRRSNPPSRKG-----------SGFGHRLSPE- 242
+G+C++LN+ E+++L IR +R P G+ + P+
Sbjct: 239 TGLCLLLNIWEMLHLGFGTIRDSLNSKRRELEDPGAYNYPFTWNTPSAPPGYNIAVKPDQ 298
Query: 243 ------------YKQNEINKLLSEQDGSLKDIL 263
YKQN+ N +Q GS ++ L
Sbjct: 299 IQYTELSNAKIAYKQNKANTAQEQQYGSHEENL 331
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 154 bits (389), Expect = 8e-38
Identities = 86/221 (38%), Positives = 120/221 (54%), Gaps = 1/221 (0%)
Query: 3 WTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNS 62
W L +LL V S +GR+WL V+ IFRI+VL +V+ DE+ F+CNTLQPGC
Sbjct: 4 WAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQ 63
Query: 63 VCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKR 122
CYD+ FP+SH R W ++L+S P +L ++ H+ E P E
Sbjct: 64 TCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCA 123
Query: 123 HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVS 182
+ Y++SV RLL E F+ LLY G+ + C PCP+TVDCFVS
Sbjct: 124 PCALRARRARRCYLLSVALRLLAELTFLGGQALLY-GFRVAPHFACAGPPCPHTVDCFVS 182
Query: 183 RPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQR 223
RPTEKTVF +F A + +L+VAE+ +L+ + R +R
Sbjct: 183 RPTEKTVFVLFYFAVGLLSALLSVAELGHLLWKGRPRAGER 223
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 142 bits (359), Expect = 3e-34
Identities = 88/281 (31%), Positives = 142/281 (50%), Gaps = 13/281 (4%)
Query: 9 LLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQF 68
L+ +N + T +G++W + + R++V+V+A V+ DE+ F+CNTLQPGC +VCYD F
Sbjct: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
Query: 69 FPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHIS 128
P+SH+R W +Q + V P+ + +++V H + L DP +R
Sbjct: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLH-RGATLAALGPRRCPDPREPASGQRRCPRPF 128
Query: 129 GTLWWT--------YVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
G Y+I ++ R L EA F + Y L+ G+ + C PC VDC+
Sbjct: 129 GERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCY 187
Query: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS 240
VSRPTEK++ +F+ A S + +L +A++V + R RR ++P RK SG
Sbjct: 188 VSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQSGASGHAE 247
Query: 241 PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCS 281
E + E++G+ R+ G GAG ++ R S
Sbjct: 248 GRRTDEEGGR---EEEGAPAPPGARAGGEGAGSPRRTSRVS 285
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 126 bits (317), Expect = 2e-29
Identities = 73/212 (34%), Positives = 114/212 (53%), Gaps = 9/212 (4%)
Query: 6 LYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCY 65
L LL+ +R ST +GR+ L V+ FR+++L + V+GDE+S F+C+T QPGC + C+
Sbjct: 6 LRRLLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACF 65
Query: 66 DQFFPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHG-DPLHLEEVKRHK 124
D F P+S +R W Q+ILV+ P+ A+++ + L G G + L + +
Sbjct: 66 DAFHPLSPLRFWVFQVILVAVPS---ALYMGFTLYHVIWHWELSGKGKEEETLIQGREGN 122
Query: 125 VHISGT----LWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
+ G L W YV + RL+ E + + Y LY G+ M C PC ++ C
Sbjct: 123 TDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLY-GFQMPSSFACRREPCLGSITCN 181
Query: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYL 212
+SRP+EKT+F M SG C++ E+V L
Sbjct: 182 LSRPSEKTIFLKTMFGVSGFCLLFTFLELVLL 213
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 114 bits (284), Expect = 1e-25
Identities = 44/98 (44%), Positives = 72/98 (73%)
Query: 1 MNWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGC 60
M+W+ L LL ++ HST +G+VWL+V+ +FRI++ V E+++ DE++ F CNT QPGC
Sbjct: 4 MSWSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGC 63
Query: 61 NSVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQ 98
++VCYD F P+SHVR W Q++++STP+++ + H+
Sbjct: 64 DNVCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHR 101
Score = 80.9 bits (198), Expect = 1e-15
Identities = 43/108 (39%), Positives = 61/108 (56%), Gaps = 2/108 (1%)
Query: 122 RHKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFV 181
R ++ G L YV +V R FE F+ YLLY G+ + C PCP+ VDCFV
Sbjct: 201 RRRIQREG-LMRVYVAQLVARAAFEVAFLVGQYLLY-GFEVRPFFPCSRQPCPHVVDCFV 258
Query: 182 SRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPS 229
SRPTEKTVF + M S +C++LN+ E+ +L + + + R PP+
Sbjct: 259 SRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGRRGPPA 306
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 113 bits (283), Expect = 2e-25
Identities = 50/97 (51%), Positives = 70/97 (72%), Gaps = 1/97 (1%)
Query: 3 WTGLYTLL-SGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
WT L LL + V +HST IGR+ L+V+ IFRI+++ + E+V+ DE++ F+CNTLQPGCN
Sbjct: 4 WTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCN 63
Query: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQ 98
CYD+ FPISH+R W Q+I+V TP+L + HQ
Sbjct: 64 QACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQ 100
Score = 87.0 bits (214), Expect = 2e-17
Identities = 46/93 (49%), Positives = 62/93 (66%), Gaps = 4/93 (4%)
Query: 135 YVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFM 194
Y+I VVFR E F+ Y LY G+++ L +C+ YPC V+C+VSRPTEKTVF VFM
Sbjct: 199 YIIQVVFRNALEIGFLVGQYFLY-GFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVFM 257
Query: 195 LAASGICIILNVAEVVYL---IIRACARRAQRR 224
A SGIC++LN+AE+ +L I+ R AQ +
Sbjct: 258 FAVSGICVVLNLAELNHLGWRKIKLAVRGAQAK 290
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 85.5 bits (210), Expect = 5e-17
Identities = 36/82 (43%), Positives = 57/82 (69%)
Query: 9 LLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQF 68
LL+ + HST +GR+ V+ FR+++L + V+GDE+S F+C+T QPGC + C+D F
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 69 FPISHVRLWSLQLILVSTPALL 90
P+S +R W Q+ILV+ P++L
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVL 109
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 85.5 bits (210), Expect = 5e-17
Identities = 36/82 (43%), Positives = 57/82 (69%)
Query: 9 LLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQF 68
LL+ + HST +GR+ V+ FR+++L + V+GDE+S F+C+T QPGC + C+D F
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 69 FPISHVRLWSLQLILVSTPALL 90
P+S +R W Q+ILV+ P++L
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVL 109
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 85.5 bits (210), Expect = 5e-17
Identities = 36/82 (43%), Positives = 57/82 (69%)
Query: 9 LLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQF 68
LL+ + HST +GR+ V+ FR+++L + V+GDE+S F+C+T QPGC + C+D F
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 69 FPISHVRLWSLQLILVSTPALL 90
P+S +R W Q+ILV+ P++L
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVL 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.139 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,090,254
Number of Sequences: 37866
Number of extensions: 454371
Number of successful extensions: 1478
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1386
Number of HSP's gapped (non-prelim): 62
length of query: 283
length of database: 18,247,518
effective HSP length: 101
effective length of query: 182
effective length of database: 14,423,052
effective search space: 2624995464
effective search space used: 2624995464
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.