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Search of human proteins with 148231605
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148231605 ovochymase 2 [Homo sapiens]
(564 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148231605 ovochymase 2 [Homo sapiens] 1162 0.0
gi|110815798 ovochymase 1 [Homo sapiens] 316 4e-86
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 184 2e-46
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 178 1e-44
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 172 1e-42
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 168 1e-41
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 167 2e-41
gi|117956391 protease, serine, 33 [Homo sapiens] 166 4e-41
gi|33695155 hepsin [Homo sapiens] 165 9e-41
gi|4504481 hepsin [Homo sapiens] 165 9e-41
gi|4506153 prostasin preproprotein [Homo sapiens] 164 2e-40
gi|58218970 protease, serine, 36 [Homo sapiens] 164 3e-40
gi|223942069 enterokinase precursor [Homo sapiens] 162 8e-40
gi|13994276 marapsin [Homo sapiens] 159 6e-39
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 157 2e-38
gi|4503627 coagulation factor XI precursor [Homo sapiens] 157 2e-38
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 157 3e-38
gi|33186882 testis serine protease 2 [Homo sapiens] 156 4e-38
gi|118498341 chymotrypsin B1 [Homo sapiens] 156 5e-38
gi|11545839 protease, serine, 22 [Homo sapiens] 155 7e-38
gi|118498350 chymotrypsin B2 [Homo sapiens] 154 2e-37
gi|145275213 coagulation factor XII precursor [Homo sapiens] 154 3e-37
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 152 6e-37
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 152 6e-37
gi|4503137 chymotrypsin-like [Homo sapiens] 152 6e-37
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 152 8e-37
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 152 8e-37
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 152 8e-37
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 152 1e-36
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 152 1e-36
>gi|148231605 ovochymase 2 [Homo sapiens]
Length = 564
Score = 1162 bits (3007), Expect = 0.0
Identities = 564/564 (100%), Positives = 564/564 (100%)
Query: 1 MLISRNKLILLLGIVFFERGKSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEK 60
MLISRNKLILLLGIVFFERGKSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEK
Sbjct: 1 MLISRNKLILLLGIVFFERGKSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEK 60
Query: 61 GSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQ 120
GSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQ
Sbjct: 61 GSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQ 120
Query: 121 TLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAG 180
TLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAG
Sbjct: 121 TLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAG 180
Query: 181 WGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDS 240
WGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDS
Sbjct: 181 WGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDS 240
Query: 241 GGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQT 300
GGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQT
Sbjct: 241 GGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQT 300
Query: 301 GNRRKSSRAWCSEQDVIVSGAEGKLHFPESLHLYYESKQRCVWTLLVPEEMHVLLSFSHL 360
GNRRKSSRAWCSEQDVIVSGAEGKLHFPESLHLYYESKQRCVWTLLVPEEMHVLLSFSHL
Sbjct: 301 GNRRKSSRAWCSEQDVIVSGAEGKLHFPESLHLYYESKQRCVWTLLVPEEMHVLLSFSHL 360
Query: 361 DVESCHHSYLSMYSLEDRPIGKFCGESLPSSILIGSNSLRLKFVSDATDNAAGFNLTYKA 420
DVESCHHSYLSMYSLEDRPIGKFCGESLPSSILIGSNSLRLKFVSDATDNAAGFNLTYKA
Sbjct: 361 DVESCHHSYLSMYSLEDRPIGKFCGESLPSSILIGSNSLRLKFVSDATDNAAGFNLTYKA 420
Query: 421 LKPNYIPDSGCSYLTVLFEEGLIQSLNYPENYSDKANCDWIFQASKHHLIKLSFQSLEIE 480
LKPNYIPDSGCSYLTVLFEEGLIQSLNYPENYSDKANCDWIFQASKHHLIKLSFQSLEIE
Sbjct: 421 LKPNYIPDSGCSYLTVLFEEGLIQSLNYPENYSDKANCDWIFQASKHHLIKLSFQSLEIE 480
Query: 481 ESGDCTSDYVTVHSDVERKKEIARLCGYDVPTPVLSPSSIMLISFQSDENGTCRGFQATV 540
ESGDCTSDYVTVHSDVERKKEIARLCGYDVPTPVLSPSSIMLISFQSDENGTCRGFQATV
Sbjct: 481 ESGDCTSDYVTVHSDVERKKEIARLCGYDVPTPVLSPSSIMLISFQSDENGTCRGFQATV 540
Query: 541 SFIPKAGKKIELPTLWFPVLILVM 564
SFIPKAGKKIELPTLWFPVLILVM
Sbjct: 541 SFIPKAGKKIELPTLWFPVLILVM 564
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 316 bits (809), Expect = 4e-86
Identities = 195/566 (34%), Positives = 296/566 (52%), Gaps = 59/566 (10%)
Query: 2 LISRNKLILLLGIVFFERGKSATLSLPKAPSCGQSLVKV---QPWNYFNIFSRILGGSQV 58
L++ L+LLL I G +L L CG +V + +P FSRI
Sbjct: 3 LLASAGLLLLLVI-----GHPRSLGL----KCGIRMVNMKSKEPAVGSRFFSRISSWRNS 53
Query: 59 EKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCI--ANRNIVSTLNVTAGEYDLSQTD 116
+PWQVSLK + H CGGS++ V+TAAHC+ + + + VT+GEY L Q D
Sbjct: 54 TVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKD 113
Query: 117 PGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFIC 176
EQ + + +I HP +++++ M DIALL + +FG+ V PICLP+ ++ E G +C
Sbjct: 114 KQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILC 173
Query: 177 TTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDAC 236
++GWG++++ S VLQE+ LPI+ C L ++ P G+T LC GFPD G DAC
Sbjct: 174 LSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRTMLCAGFPDWGMDAC 233
Query: 237 QGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRG---WRNNVRKSDQGSPGIFTDISKVLPW 293
QGDSGG L+CR G W LAG+TSW GC G RNN K+ S GIF+ +S+++ +
Sbjct: 234 QGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRNNHVKA---SLGIFSKVSELMDF 290
Query: 294 IHEHIQTGNRRKSSRAWCSEQDVIVSGAEGKLHFPESLHLYYE--SKQRCVWTLLVPEEM 351
I +++ TG R + G + ++L E QR L + +++
Sbjct: 291 ITQNLFTGLDRGQPLS-----------KVGSRYITKALSSVQEVNGSQRGKGILDMEKQV 339
Query: 352 HVLLSFSHLDVESCHHSYLSMYS-----------LED--RPIGKFCGESLPSSILIGSNS 398
C H Y+S+ S +ED + + CG+ LPS +L ++
Sbjct: 340 ------------GCDHDYVSLRSSSGVLFNQRSLMEDDGKQNKRVCGKILPSPLLAETSE 387
Query: 399 LRLKFVSDATDNAAGFNLTYKALKPNYIPDSGCSYLTVLFEEGLIQSLNYPENYSDKANC 458
+ FVSD D+ +GF LT A++ + SGC L +L EEG S YP+ Y C
Sbjct: 388 AMVPFVSDTEDSGSGFELTVTAVQKSE-AGSGCGSLAILVEEGTNHSAKYPDLYPSNTRC 446
Query: 459 DWIFQASKHHLIKLSFQSLEIEESGDCTSDYVTVHSDVERKKEIARLCGYDVPTPVLSPS 518
W A + H+IKL+F+ ++ S +C D V ++ D E K ++A+LCG T + S S
Sbjct: 447 HWFICAPEKHIIKLTFEDFAVKFSPNCIYDAVVIYGDSEEKHKLAKLCGMLTITSIFSSS 506
Query: 519 SIMLISFQSDENGTCRGFQATVSFIP 544
++ +I F+SD +GF+A + +P
Sbjct: 507 NMTVIYFKSDGKNRLQGFKARFTILP 532
Score = 178 bits (452), Expect = 1e-44
Identities = 137/504 (27%), Positives = 222/504 (44%), Gaps = 67/504 (13%)
Query: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEY 110
RI GG + +PWQV L+ + CGG+I++P W++TAAHC+ +N + + AG++
Sbjct: 574 RIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDH 633
Query: 111 DLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQF 170
D + + EQ + +I+H F+T D DIAL++++ ++ V P+CLP E
Sbjct: 634 DRNLKESTEQVRRAKHIIVHEDFNTLS-YDSDIALIQLSSPLEYNSVVRPVCLPHSAEPL 692
Query: 171 EAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGF-P 229
+ IC GWG ++ G L+ LQ++ + +L E C + + +C GF
Sbjct: 693 FSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAA 752
Query: 230 DGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISK 289
G +D CQGDSGG L+CR++ G + L G+ SWG GC + W+ PG+F +
Sbjct: 753 SGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWK----------PGVFARVMI 802
Query: 290 VLPWIHEHI------QTGNRRKS-------------SRAW---CSEQDVIVSGAEGKLHF 327
L WI I QT N+ K+ S +W CSE ++ + + F
Sbjct: 803 FLDWIQSKINGPASLQTNNKCKTLKQQLPPPTPSPDSASWPGCCSEAEL----EKPRGFF 858
Query: 328 PESLHLY-YESKQRCVWTLLVPEEMHVLLSFSHLDV---ESCHHSYLSMYS---LEDRPI 380
P +L Y + C W L V + +L + C S L +Y + +
Sbjct: 859 PTPRYLLDYRGRLECSWVLRVSASSMAKFTIEYLSLLGSPVCQDSVLIIYEERHSKRKTA 918
Query: 381 GKFCGESLPSSILIGSNSLRLKFVSDATDNAAGFNLTYKALKPNYIPDS----------- 429
G G L S + L ++ A A F ++Y LK DS
Sbjct: 919 GGLHGRRLYSMTFMSPGPL-VRVTFHALVRGA-FGISYIVLKVLGPKDSKITRLSQSSNR 976
Query: 430 ----GCSYLTVLFEEGLIQSLNYPEN-YSDKANCDWIFQASKHHLIKLSFQSLEIEESGD 484
C + + EG++Q P N + C W A +H+I+L+ + ++ +
Sbjct: 977 EHLVPCEDVLLTKPEGIMQ---IPRNSHRTTMGCQWRLVAPLNHIIQLNIINFPMKPTTF 1033
Query: 485 CTSDYVTVHSDV-ERKKEIARLCG 507
++ V+ KK IA G
Sbjct: 1034 VCHGHLRVYEGFGPGKKLIASFAG 1057
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 11/81 (13%)
Query: 477 LEIEESGDCTSDYVTVHSDV-----------ERKKEIARLCGYDVPTPVLSPSSIMLISF 525
L++E+ C DYV++ S + K+ R+CG +P+P+L+ +S ++ F
Sbjct: 333 LDMEKQVGCDHDYVSLRSSSGVLFNQRSLMEDDGKQNKRVCGKILPSPLLAETSEAMVPF 392
Query: 526 QSDENGTCRGFQATVSFIPKA 546
SD + GF+ TV+ + K+
Sbjct: 393 VSDTEDSGSGFELTVTAVQKS 413
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 184 bits (467), Expect = 2e-46
Identities = 96/249 (38%), Positives = 140/249 (56%), Gaps = 17/249 (6%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTL--NVTA 107
SRI+GG+ +G +PWQ SL+ R +HICGG++++ +WVITAAHC ++ ST+ V
Sbjct: 575 SRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHCFQEDSMASTVLWTVFL 634
Query: 108 GEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELR 167
G+ + PGE + + +++HP+ + DYD+ALL++ V P+CLP
Sbjct: 635 GKVWQNSRWPGEVSFKVSRLLLHPYHE-EDSHDYDVALLQLDHPVVRSAAVRPVCLPARS 693
Query: 168 EQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTG 227
FE G C GWG L EGG +S LQ+V++ ++ + C P LC G
Sbjct: 694 HFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQVTP----RMLCAG 749
Query: 228 FPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDI 287
+ G +DACQGDSGG L+C+ G W LAG+ SWGLGCGR G++T I
Sbjct: 750 YRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGR----------PNYFGVYTRI 799
Query: 288 SKVLPWIHE 296
+ V+ WI +
Sbjct: 800 TGVISWIQQ 808
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 178 bits (451), Expect = 1e-44
Identities = 91/256 (35%), Positives = 142/256 (55%), Gaps = 18/256 (7%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQR---QKHICGGSIVSPQWVITAAHCIANRNIVSTLNVT 106
+RI+GG+ G +PWQVSL+ + Q+H+CGGS++ QWV+TAAHC + +
Sbjct: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448
Query: 107 AGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPEL 166
+G +LS I+ +IIH ++ + ++DIAL+K+ + F PICLP
Sbjct: 449 SGILNLSDITKDTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSK 507
Query: 167 REQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCT 226
+ C GWG E G + +LQ+VN+P++T EEC K + +C
Sbjct: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK---ITQRMVCA 564
Query: 227 GFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTD 286
G+ +GG+DAC+GDSGG L+C++ G W L G+TSWG GC R + PG++T
Sbjct: 565 GYKEGGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCAR----------REQPGVYTK 613
Query: 287 ISKVLPWIHEHIQTGN 302
+++ + WI E Q+ +
Sbjct: 614 VAEYMDWILEKTQSSD 629
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 172 bits (435), Expect = 1e-42
Identities = 88/251 (35%), Positives = 141/251 (56%), Gaps = 17/251 (6%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGE 109
SRI+GG+ +PWQ SL+ + H+CGGS+++P W+ITAAHC+ + + + + G
Sbjct: 215 SRIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGL 274
Query: 110 YDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQ 169
+S D + +E ++ H + K+ + DIAL+K+AG F + P+CLP E
Sbjct: 275 --VSLLDNPAPSHLVEKIVYHSKYKPKR-LGNDIALMKLAGPLTFNEMIQPVCLPNSEEN 331
Query: 170 FEAGFICTTAGWGRLTEG-GVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGF 228
F G +C T+GWG +G G S VL +P+++ + C + I + LC G+
Sbjct: 332 FPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHR--DVYGGIISPSMLCAGY 389
Query: 229 PDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDIS 288
GG D+CQGDSGG L+C+ ++ W L G TS+G+GC ++ PG++T ++
Sbjct: 390 LTGGVDSCQGDSGGPLVCQERR-LWKLVGATSFGIGC----------AEVNKPGVYTRVT 438
Query: 289 KVLPWIHEHIQ 299
L WIHE ++
Sbjct: 439 SFLDWIHEQME 449
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 168 bits (426), Expect = 1e-41
Identities = 94/252 (37%), Positives = 135/252 (53%), Gaps = 20/252 (7%)
Query: 50 SRILGGSQVEKGSYPWQVSL-KQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAG 108
+RI+GGS +G +PWQVSL +R++H CG +V+ +W+++AAHC G
Sbjct: 825 TRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLG 884
Query: 109 EYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELRE 168
LS + Q + + HP ++ +DYD+ALL++AG + V PICLPE
Sbjct: 885 TPFLSGAEG--QLERVARIYKHPFYNLYT-LDYDVALLELAGPVRRSRLVRPICLPEPAP 941
Query: 169 QFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPIS-GKTFLCTG 227
+ G C GWG + EGG +++ LQ+ + +L+ + C P+ LC G
Sbjct: 942 RPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFY-----PVQISSRMLCAG 996
Query: 228 FPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDI 287
FP GG D+C GD+GG L CR G W L GVTSWG GCGR PG++T +
Sbjct: 997 FPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGR----------PHFPGVYTRV 1046
Query: 288 SKVLPWIHEHIQ 299
+ V WI +HIQ
Sbjct: 1047 AAVRGWIGQHIQ 1058
Score = 159 bits (402), Expect = 6e-39
Identities = 87/273 (31%), Positives = 141/273 (51%), Gaps = 24/273 (8%)
Query: 25 LSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSP 84
+++PK CG +P +R++GG G PWQVSLK+ +H CG ++V
Sbjct: 484 VTVPKLQECGARPAMEKP-------TRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGD 536
Query: 85 QWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIA 144
+W+++AAHC N V + G L + + V++HP ++ +D+D+A
Sbjct: 537 RWLLSAAHCF-NHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGI-LDFDLA 594
Query: 145 LLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVLS-QVLQEVNLPILT 203
+L++A F ++ P+CLP ++F G C +GWG EG ++LQ+ ++ I+
Sbjct: 595 VLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIID 654
Query: 204 WEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGL 263
+ C L +C GF +G D+CQGDSGG L C G + LAG+ SWG+
Sbjct: 655 QKTCSV----LYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGI 710
Query: 264 GCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHE 296
GC + V+K PG++T I+++ WI E
Sbjct: 711 GCAQ-----VKK-----PGVYTRITRLKGWILE 733
Score = 149 bits (377), Expect = 5e-36
Identities = 76/247 (30%), Positives = 126/247 (51%), Gaps = 16/247 (6%)
Query: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEY 110
RI+GG + G +PWQ SL++ ++H CG +I++ +W+++AAHC + G
Sbjct: 202 RIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGAT 261
Query: 111 DLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQF 170
LS ++ + ++ HP ++ D+D+A+L++ FG + P+CLP F
Sbjct: 262 YLSGSEASTVRAQVVQIVKHPLYNADTA-DFDVAVLELTSPLPFGRHIQPVCLPAATHIF 320
Query: 171 EAGFICTTAGWGRLTEGGVLS-QVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFP 229
C +GWG L E ++ +VLQ+ + +L C + L +C G+
Sbjct: 321 PPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCAS----LYGHSLTDRMVCAGYL 376
Query: 230 DGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISK 289
DG D+CQGDSGG L+C G + LAG+ SWG+GC R PG++ +++
Sbjct: 377 DGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARR----------PGVYARVTR 426
Query: 290 VLPWIHE 296
+ WI E
Sbjct: 427 LRDWILE 433
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 167 bits (423), Expect = 2e-41
Identities = 94/256 (36%), Positives = 139/256 (54%), Gaps = 24/256 (9%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNI--VSTLNVTA 107
SRI+GG V G +PWQ S+ +H CGGS+++P+WV+TAAHC+ + + +S+ V A
Sbjct: 216 SRIVGGQSVAPGRWPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHA 275
Query: 108 GEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELR 167
G S P + L +E +I HP +S + DYD+ALL++ A F VG +CLP
Sbjct: 276 GLVSHSAVRPHQGAL-VERIIPHPLYSAQN-HDYDVALLRLQTALNFSDTVGAVCLPAKE 333
Query: 168 EQFEAGFICTTAGWGRLTEGGVL-SQVLQEVNLPILTWEECVAALLTLKRPISG---KTF 223
+ F G C +GWG S +LQ+ +P+ + + C ++ + SG
Sbjct: 334 QHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCV-----YSGALTPRM 388
Query: 224 LCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGI 283
LC G+ DG DACQGDSGG L+C + W L GV SWG GC ++ PG+
Sbjct: 389 LCAGYLDGRADACQGDSGGPLVCPD-GDTWRLVGVVSWGRGC----------AEPNHPGV 437
Query: 284 FTDISKVLPWIHEHIQ 299
+ +++ L WIH+ Q
Sbjct: 438 YAKVAEFLDWIHDTAQ 453
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 166 bits (421), Expect = 4e-41
Identities = 103/298 (34%), Positives = 143/298 (47%), Gaps = 37/298 (12%)
Query: 8 LILLLGIVFFERGKSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQV 67
L+L+LG + KSA +CGQ + SRI+GG G +PWQ
Sbjct: 11 LLLVLGAAGTQGRKSA--------ACGQPRMS----------SRIVGGRDGRDGEWPWQA 52
Query: 68 SLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETV 127
S++ R H+CGGS+++PQWV+TAAHC R + + V G L T P ++ + V
Sbjct: 53 SIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRV 112
Query: 128 IIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEG 187
++ P +S D+ALL++ V P+CLP + G C GWG L G
Sbjct: 113 LLPPDYSEDGARG-DLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPG 171
Query: 188 GVLSQ--VLQEVNLPILTWEEC-----VAALLTLKRPISGKTFLCTGFPDGGRDACQGDS 240
L + LQ V +P+L C V A + I LC G+P G +DACQGDS
Sbjct: 172 VPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDS 231
Query: 241 GGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHI 298
GG L C + G+W L GV SWG GC R PG++T ++ PWI +
Sbjct: 232 GGPLTCL-QSGSWVLVGVVSWGKGCALPNR----------PGVYTSVATYSPWIQARV 278
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 165 bits (418), Expect = 9e-41
Identities = 93/259 (35%), Positives = 133/259 (51%), Gaps = 23/259 (8%)
Query: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRN-IVSTLNVTAGE 109
RI+GG G +PWQVSL+ H+CGGS++S WV+TAAHC RN ++S V AG
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA 221
Query: 110 YDLSQTDPGEQTLTIETVIIHPHF-----STKKPMDYDIALLKMAGAFQFGHFVGPICLP 164
++Q P L ++ V+ H + + DIAL+ ++ ++ P+CLP
Sbjct: 222 --VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 279
Query: 165 ELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFL 224
+ G ICT GWG G + VLQE +PI++ + C A I K F
Sbjct: 280 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADF-YGNQIKPKMF- 337
Query: 225 CTGFPDGGRDACQGDSGGSLMCR---NKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSP 281
C G+P+GG DACQGDSGG +C ++ W L G+ SWG GC + P
Sbjct: 338 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQK----------P 387
Query: 282 GIFTDISKVLPWIHEHIQT 300
G++T +S WI + I+T
Sbjct: 388 GVYTKVSDFREWIFQAIKT 406
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 165 bits (418), Expect = 9e-41
Identities = 93/259 (35%), Positives = 133/259 (51%), Gaps = 23/259 (8%)
Query: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRN-IVSTLNVTAGE 109
RI+GG G +PWQVSL+ H+CGGS++S WV+TAAHC RN ++S V AG
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA 221
Query: 110 YDLSQTDPGEQTLTIETVIIHPHF-----STKKPMDYDIALLKMAGAFQFGHFVGPICLP 164
++Q P L ++ V+ H + + DIAL+ ++ ++ P+CLP
Sbjct: 222 --VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLP 279
Query: 165 ELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFL 224
+ G ICT GWG G + VLQE +PI++ + C A I K F
Sbjct: 280 AAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADF-YGNQIKPKMF- 337
Query: 225 CTGFPDGGRDACQGDSGGSLMCR---NKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSP 281
C G+P+GG DACQGDSGG +C ++ W L G+ SWG GC + P
Sbjct: 338 CAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQK----------P 387
Query: 282 GIFTDISKVLPWIHEHIQT 300
G++T +S WI + I+T
Sbjct: 388 GVYTKVSDFREWIFQAIKT 406
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 164 bits (416), Expect = 2e-40
Identities = 87/255 (34%), Positives = 129/255 (50%), Gaps = 18/255 (7%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGE 109
+RI GGS G +PWQVS+ H+CGGS+VS QWV++AAHC + + V G
Sbjct: 43 ARITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGA 102
Query: 110 YDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQ 169
+ L + T++ +I HP + ++ DIALL+++ F ++ PICLP
Sbjct: 103 HQLDSYSEDAKVSTLKDIIPHPSY-LQEGSQGDIALLQLSRPITFSRYIRPICLPAANAS 161
Query: 170 FEAGFICTTAGWGRLTEGGVL--SQVLQEVNLPILTWEECVAALLTLKRP----ISGKTF 223
F G CT GWG + L + LQ++ +P+++ E C +P +
Sbjct: 162 FPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHFVQEDM 221
Query: 224 LCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGI 283
+C G+ +GG+DACQGDSGG L C +G W L G+ SWG CG + PG+
Sbjct: 222 VCAGYVEGGKDACQGDSGGPLSC-PVEGLWYLTGIVSWGDACGA----------RNRPGV 270
Query: 284 FTDISKVLPWIHEHI 298
+T S WI +
Sbjct: 271 YTLASSYASWIQSKV 285
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 164 bits (414), Expect = 3e-40
Identities = 93/259 (35%), Positives = 135/259 (52%), Gaps = 23/259 (8%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIV---STLNVT 106
+RI+GGS + G++PWQVSL HICGGS+++P WV++AAHC + + +V
Sbjct: 45 ARIVGGSNAQPGTWPWQVSLHHGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAEWSVL 104
Query: 107 AGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPEL 166
G + G T + +++ ++S + + D+ALL++A G V P+CLP
Sbjct: 105 LGVHSQDGPLDGAHTRAVAAIVVPANYS-QVELGADLALLRLASPASLGPAVWPVCLPRA 163
Query: 167 REQFEAGFICTTAGWGRLTEGG--VLSQVLQEVNLPILTWEECVAALLTLKRPISGKT-- 222
+F G C GWG + E L VLQEV L +L C L + P +
Sbjct: 164 SHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATC-QCLYSQPGPFNLTLQI 222
Query: 223 ---FLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQG 279
LC G+P+G RD CQGDSGG L+C + G W AG+TS+G GCGR +
Sbjct: 223 LPGMLCAGYPEGRRDTCQGDSGGPLVC-EEGGRWFQAGITSFGFGCGR----------RN 271
Query: 280 SPGIFTDISKVLPWIHEHI 298
PG+FT ++ WI E +
Sbjct: 272 RPGVFTAVATYEAWIREQV 290
Score = 70.5 bits (171), Expect = 4e-12
Identities = 66/261 (25%), Positives = 101/261 (38%), Gaps = 26/261 (9%)
Query: 55 GSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVST--LNVTAGEYDL 112
G G++PW+ + C G++VS WV+ A C + N + ++ A L
Sbjct: 326 GKAPRPGAWPWEAQVMVPGSRPCHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVLL 385
Query: 113 SQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEA 172
E+ + ++ H + S D+ALL++ P+CLP F
Sbjct: 386 PSRPRAER---VARLVQHENASWDNAS--DLALLQLRTPVNLSAASRPVCLPHPEHYFLP 440
Query: 173 GFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKT--FLCTGFPD 230
G C A WGR E + L E L W C+ P+ G LC + +
Sbjct: 441 GSRCRLARWGR-GEPALGPGALLEAELLGGWWCHCLYGRQGAAVPLPGDPPHALCPAYQE 499
Query: 231 GGR-DACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISK 289
+C DS SL+C+ ++G W LAG+ + GC R P F +
Sbjct: 500 KEEVGSCWNDSRWSLLCQ-EEGTWFLAGIRDFPSGCLR-------------PRAFFPLQT 545
Query: 290 VLPWIHEHIQTGNRRKSSRAW 310
PWI H+ G + AW
Sbjct: 546 HGPWI-SHVTRGAYLEDQLAW 565
Score = 59.3 bits (142), Expect = 9e-09
Identities = 57/243 (23%), Positives = 90/243 (37%), Gaps = 35/243 (14%)
Query: 63 YPWQVSLKQRQKHICGGSIVSPQWVITAAHCI--ANRNIVSTLNVTAGEYDLSQTDPGEQ 120
+PW + +C G +++P WV+ A HC+ V + V G S G Q
Sbjct: 601 WPWLAEVHVAGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQGHQ 660
Query: 121 TLTIETVIIHP-HFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTA 179
+ I P H + P +ALL+++ + PICL G C
Sbjct: 661 VSRLVISIRLPQHLGLRPP----LALLELSSRVEPSPSALPICLHP--AGIPPGASCWVL 714
Query: 180 GWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGD 239
GW + +V + ILT C L + I LC + +G + C+
Sbjct: 715 GWKEPQD-----RVPVAAAVSILTQRICDC----LYQGILPPGTLCVLYAEGQENRCEMT 765
Query: 240 SGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQ 299
S L+C+ +G+W L G+ + QGS +F I WI + +
Sbjct: 766 SAPPLLCQMTEGSWILVGM-----------------AVQGSRELFAAIGPEEAWISQTVG 808
Query: 300 TGN 302
N
Sbjct: 809 EAN 811
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 162 bits (410), Expect = 8e-40
Identities = 90/269 (33%), Positives = 144/269 (53%), Gaps = 23/269 (8%)
Query: 32 SCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAA 91
SCG+ L +I +I+GGS ++G++PW V L + +CG S+VS W+++AA
Sbjct: 771 SCGKKLAAQ------DITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAA 824
Query: 92 HCIANRNIV-STLNVTAGEYDLSQ-TDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMA 149
HC+ RN+ S G + S T P I+ ++I+PH++ ++ D DIA++ +
Sbjct: 825 HCVYGRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRK-DNDIAMMHLE 883
Query: 150 GAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVA 209
+ ++ PICLPE + F G C+ AGWG + G + +LQE ++P+L+ E C
Sbjct: 884 FKVNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQ 943
Query: 210 ALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGW 269
+ + +C G+ +GG D+CQGDSGG LMC+ + W LAGVTS+G C
Sbjct: 944 QMPEYN---ITENMICAGYEEGGIDSCQGDSGGPLMCQ-ENNRWFLAGVTSFGYKCALPN 999
Query: 270 RNNVRKSDQGSPGIFTDISKVLPWIHEHI 298
R PG++ +S+ WI +
Sbjct: 1000 R----------PGVYARVSRFTEWIQSFL 1018
Score = 36.2 bits (82), Expect = 0.082
Identities = 16/40 (40%), Positives = 22/40 (55%)
Query: 445 SLNYPENYSDKANCDWIFQASKHHLIKLSFQSLEIEESGD 484
S N+P +Y + A C WI A K I+L FQ ++E D
Sbjct: 539 STNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENIND 578
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 159 bits (402), Expect = 6e-39
Identities = 98/299 (32%), Positives = 149/299 (49%), Gaps = 40/299 (13%)
Query: 9 ILLLGIVFFERGKSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVS 68
+LLL +R K+AT +CG+ + +R++GG ++G +PWQVS
Sbjct: 9 LLLLLCFGSQRAKAAT-------ACGRP----------RMLNRMVGGQDTQEGEWPWQVS 51
Query: 69 LKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVI 128
+++ H CGGS+++ QWV+TAAHC N + S V G L Q P + V
Sbjct: 52 IQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYARVRQVE 111
Query: 129 IHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGG 188
+P + D+AL+++ F +++ P+CLP+ FE G C GWG +E
Sbjct: 112 SNPLYQ-GTASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCWVTGWGSPSEED 170
Query: 189 VLSQ--VLQEVNLPILTWEECVAALLTLKRPISG-------KTFLCTGFPDGGRDACQGD 239
+L + +LQ++ +PI+ +C LL K G LC GF +G +DAC+GD
Sbjct: 171 LLPEPRILQKLAVPIIDTPKC--NLLYSKDTEFGYQPKTIKNDMLCAGFEEGKKDACKGD 228
Query: 240 SGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHI 298
SGG L+C + +W AGV SWG GC R Q PG++ ++ WIH I
Sbjct: 229 SGGPLVCLVGQ-SWLQAGVISWGEGCAR----------QNRPGVYIRVTAHHNWIHRII 276
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 157 bits (398), Expect = 2e-38
Identities = 90/260 (34%), Positives = 140/260 (53%), Gaps = 20/260 (7%)
Query: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHC--IANRNIVSTLNVTAG 108
RI+GG+ +PWQVSL HICGG+++ QWV+TAAHC + ++ V AG
Sbjct: 325 RIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAG 384
Query: 109 EYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELRE 168
+L Q + +I +II+ ++ T + DYDIAL++++ + P CLP +
Sbjct: 385 TSNLHQL---PEAASIAEIIINSNY-TDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQ 440
Query: 169 QFEAGFICTTAGWGRLTE-GGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTG 227
F C G+G+ E S L+EV + ++ +++C L + +C G
Sbjct: 441 TFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYL--VYDSYLTPRMMCAG 498
Query: 228 FPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDI 287
GGRD+CQGDSGG L+C + W LAGVTSWG GCG+ + PG++T +
Sbjct: 499 DLRGGRDSCQGDSGGPLVC-EQNNRWYLAGVTSWGTGCGQ----------RNKPGVYTKV 547
Query: 288 SKVLPWIHEHIQTGNRRKSS 307
++VLPWI+ +++ R + S
Sbjct: 548 TEVLPWIYSKMESEVRFRKS 567
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 157 bits (397), Expect = 2e-38
Identities = 88/252 (34%), Positives = 132/252 (52%), Gaps = 18/252 (7%)
Query: 51 RILGGSQVEKGSYPWQVSL---KQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTA 107
RI+GG+ +G +PWQV+L Q+H+CGGSI+ QW++TAAHC L V +
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYS 446
Query: 108 GEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELR 167
G + S+ ++ +IIH + + YDIALLK+ + PICLP
Sbjct: 447 GILNQSEIKEDTSFFGVQEIIIHDQYKMAE-SGYDIALLKLETTVNYTDSQRPICLPSKG 505
Query: 168 EQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTG 227
++ C GWG + LQ+ +P++T EEC K I+ K +C G
Sbjct: 506 DRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHK--ITHK-MICAG 562
Query: 228 FPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDI 287
+ +GG+DAC+GDSGG L C++ + W L G+TSWG GC + R PG++T++
Sbjct: 563 YREGGKDACKGDSGGPLSCKHNE-VWHLVGITSWGEGCAQRER----------PGVYTNV 611
Query: 288 SKVLPWIHEHIQ 299
+ + WI E Q
Sbjct: 612 VEYVDWILEKTQ 623
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 157 bits (396), Expect = 3e-38
Identities = 96/278 (34%), Positives = 135/278 (48%), Gaps = 26/278 (9%)
Query: 31 PSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITA 90
P CG+ V + RI+GG G++PWQ SL+ R+ H+CGGS++SPQWV+TA
Sbjct: 24 PGCGRPQVS-------DAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTA 76
Query: 91 AHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAG 150
AHC + S V GE +++ + T+ +I+H S + DIAL++++
Sbjct: 77 AHCFSGSLNSSDYQVHLGELEITLS---PHFSTVRQIILHSSPSGQPGTSGDIALVELSV 133
Query: 151 AFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVL--SQVLQEVNLPILTWEECV 208
+ P+CLPE + F G C GWG EG L L+EV + ++ E C
Sbjct: 134 PVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCR 193
Query: 209 AALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRG 268
I LC P DACQ DSGG L+C+ GAW AG+ SWG GCGR
Sbjct: 194 RDYPGPGGSILQPDMLCARGPG---DACQDDSGGPLVCQ-VNGAWVQAGIVSWGEGCGRP 249
Query: 269 WRNNVRKSDQGSPGIFTDISKVLPWIHEHIQTGNRRKS 306
R PG++T + + WI HI +S
Sbjct: 250 NR----------PGVYTRVPAYVNWIRRHITASGGSES 277
>gi|33186882 testis serine protease 2 [Homo sapiens]
Length = 293
Score = 156 bits (395), Expect = 4e-38
Identities = 82/221 (37%), Positives = 128/221 (57%), Gaps = 10/221 (4%)
Query: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEY 110
RI+GG E+G +PWQVS++ + +HICGG++V+ WV+TA HCI++R S V G+
Sbjct: 79 RIVGGVDAEEGRWPWQVSVRTKGRHICGGTLVTATWVLTAGHCISSRFHYS---VKMGDR 135
Query: 111 DLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQF 170
+ + ++++ +HP FST + D+ALL++ F + PIC+P+ Q
Sbjct: 136 SV-YNENTSVVVSVQRAFVHPKFSTVTTIRNDLALLQLQHPVNFTSNIQPICIPQENFQV 194
Query: 171 EAGFICTTAGWGRLTEGGVL-SQVLQEVNLPILTWEEC---VAALLTLKRPISGKTFLCT 226
E C GWG+ E L S++LQ+V+ I+ +EEC + L+ + + K +C
Sbjct: 195 EGRTRCWVTGWGKTPEREKLASEILQDVDQYIMCYEECNKIIQKALSSTKDVIIKGMVC- 253
Query: 227 GFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGR 267
G+ + G+D+CQGDSGG L C W G+ SWG+GCGR
Sbjct: 254 GYKEQGKDSCQGDSGGRLAC-EYNDTWVQVGIVSWGIGCGR 293
>gi|118498341 chymotrypsin B1 [Homo sapiens]
Length = 263
Score = 156 bits (394), Expect = 5e-38
Identities = 93/249 (37%), Positives = 130/249 (52%), Gaps = 24/249 (9%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQK-HICGGSIVSPQWVITAAHCIANRNIVSTLNVTAG 108
SRI+ G GS+PWQVSL+ + H CGGS++S WV+TAAHC + V V AG
Sbjct: 32 SRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDV----VVAG 87
Query: 109 EYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELRE 168
E+D + Q L I V +P FS ++ DI LLK+A +F V +CLP +
Sbjct: 88 EFDQGSDEENIQVLKIAKVFKNPKFSILT-VNNDITLLKLATPARFSQTVSAVCLPSADD 146
Query: 169 QFEAGFICTTAGWGRLT-EGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTG 227
F AG +C T GWG+ LQ+ LP+L+ EC + R I+ +C G
Sbjct: 147 DFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKK---SWGRRIT-DVMICAG 202
Query: 228 FPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDI 287
G +C GDSGG L+C+ K GAWTL G+ SWG SPG++ +
Sbjct: 203 --ASGVSSCMGDSGGPLVCQ-KDGAWTLVGIVSWGSD----------TCSTSSPGVYARV 249
Query: 288 SKVLPWIHE 296
+K++PW+ +
Sbjct: 250 TKLIPWVQK 258
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 155 bits (393), Expect = 7e-38
Identities = 96/278 (34%), Positives = 142/278 (51%), Gaps = 27/278 (9%)
Query: 27 LPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQW 86
+P P+CG K Q N R++GG +PW VS+++ H C GS+++ +W
Sbjct: 35 IPVPPACG----KPQQLN------RVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRW 84
Query: 87 VITAAHCIA-NRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIAL 145
VITAAHC N N +V G + L Q + + V HP +S K+ DIAL
Sbjct: 85 VITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIAL 144
Query: 146 LKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVL--SQVLQEVNLPILT 203
+++ + QF V PICLP+ C +GWG + +G L Q LQ++ +PI+
Sbjct: 145 VRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIID 204
Query: 204 WEECVAALL--TLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSW 261
E C + PI+ + LC G+ +G RDAC GDSGG LMC+ GAW LAG+ SW
Sbjct: 205 SEVCSHLYWRGAGQGPIT-EDMLCAGYLEGERDACLGDSGGPLMCQ-VDGAWLLAGIISW 262
Query: 262 GLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQ 299
G GC +++ PG++ +S W+ + +Q
Sbjct: 263 GEGC----------AERNRPGVYISLSAHRSWVEKIVQ 290
>gi|118498350 chymotrypsin B2 [Homo sapiens]
Length = 263
Score = 154 bits (389), Expect = 2e-37
Identities = 92/249 (36%), Positives = 130/249 (52%), Gaps = 24/249 (9%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQK-HICGGSIVSPQWVITAAHCIANRNIVSTLNVTAG 108
SRI+ G GS+PWQVSL+ + H CGGS++S WV+TAAHC + V V AG
Sbjct: 32 SRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVRTSDV----VVAG 87
Query: 109 EYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELRE 168
E+D + Q L I V +P FS ++ DI LLK+A +F V +CLP +
Sbjct: 88 EFDQGSDEENIQVLKIAKVFKNPKFSILT-VNNDITLLKLATPARFSQTVSAVCLPSADD 146
Query: 169 QFEAGFICTTAGWGRLT-EGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTG 227
F AG +C T GWG+ LQ+ LP+L+ EC + R I+ +C G
Sbjct: 147 DFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKK---SWGRRIT-DVMICAG 202
Query: 228 FPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDI 287
G +C GDSGG L+C+ K GAWTL G+ SWG R +P ++ +
Sbjct: 203 --ASGVSSCMGDSGGPLVCQ-KDGAWTLVGIVSWG----------SRTCSTTTPAVYARV 249
Query: 288 SKVLPWIHE 296
+K++PW+ +
Sbjct: 250 AKLIPWVQK 258
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 154 bits (388), Expect = 3e-37
Identities = 96/276 (34%), Positives = 141/276 (51%), Gaps = 31/276 (11%)
Query: 32 SCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAA 91
SCGQ L K + +R++GG +G++P+ +L C GS+++P WV+TAA
Sbjct: 358 SCGQRLRKS-----LSSMTRVVGGLVALRGAHPYIAALYWGHS-FCAGSLIAPCWVLTAA 411
Query: 92 HCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDY--DIALLKM- 148
HC+ +R L V G+ + + QTL + + +H FS P+ Y D+ALL++
Sbjct: 412 HCLQDRPAPEDLTVVLGQERRNHSCEPCQTLAVRSYRLHEAFS---PVSYQHDLALLRLQ 468
Query: 149 ----AGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGG-VLSQVLQEVNLPILT 203
+V P+CLP + +C AGWG EG + LQE +P L+
Sbjct: 469 EDADGSCALLSPYVQPVCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLS 528
Query: 204 WEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNK--KGAWTLAGVTSW 261
E C A + + G LC GF +GG DACQGDSGG L+C ++ + TL G+ SW
Sbjct: 529 LERCSAPDVHGSSILPG--MLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISW 586
Query: 262 GLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEH 297
G GCG D+ PG++TD++ L WI EH
Sbjct: 587 GSGCG----------DRNKPGVYTDVAYYLAWIREH 612
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 152 bits (385), Expect = 6e-37
Identities = 87/246 (35%), Positives = 128/246 (52%), Gaps = 20/246 (8%)
Query: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEY 110
R++GG + S+PWQVS++ ++H+CGGSI+ P WV+TAAHC V V AG
Sbjct: 199 RVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSD 258
Query: 111 DLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQF 170
L +L + +II F+ P D DIAL+K+ F V PICLP E+
Sbjct: 259 KLGSF----PSLAVAKIII-IEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEEL 313
Query: 171 EAGFICTTAGWGRLTE-GGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFP 229
GWG + GG +S +L + ++ ++ C A + ++ K +C G P
Sbjct: 314 TPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNAD-DAYQGEVTEK-MMCAGIP 371
Query: 230 DGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISK 289
+GG D CQGDSGG LM ++ + W + G+ SWG GCG +PG++T +S
Sbjct: 372 EGGVDTCQGDSGGPLMYQSDQ--WHVVGIVSWGYGCG----------GPSTPGVYTKVSA 419
Query: 290 VLPWIH 295
L WI+
Sbjct: 420 YLNWIY 425
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 152 bits (385), Expect = 6e-37
Identities = 87/246 (35%), Positives = 128/246 (52%), Gaps = 20/246 (8%)
Query: 51 RILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEY 110
R++GG + S+PWQVS++ ++H+CGGSI+ P WV+TAAHC V V AG
Sbjct: 204 RVVGGEEASVDSWPWQVSIQYDKQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRAGSD 263
Query: 111 DLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQF 170
L +L + +II F+ P D DIAL+K+ F V PICLP E+
Sbjct: 264 KLGSF----PSLAVAKIII-IEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEEL 318
Query: 171 EAGFICTTAGWGRLTE-GGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFP 229
GWG + GG +S +L + ++ ++ C A + ++ K +C G P
Sbjct: 319 TPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNAD-DAYQGEVTEK-MMCAGIP 376
Query: 230 DGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISK 289
+GG D CQGDSGG LM ++ + W + G+ SWG GCG +PG++T +S
Sbjct: 377 EGGVDTCQGDSGGPLMYQSDQ--WHVVGIVSWGYGCG----------GPSTPGVYTKVSA 424
Query: 290 VLPWIH 295
L WI+
Sbjct: 425 YLNWIY 430
>gi|4503137 chymotrypsin-like [Homo sapiens]
Length = 264
Score = 152 bits (385), Expect = 6e-37
Identities = 105/286 (36%), Positives = 145/286 (50%), Gaps = 38/286 (13%)
Query: 22 SATLSLPK-APSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQK-HICGG 79
S TLSL S G + ++P F+ RI+ G GS+PWQVSL+ H CGG
Sbjct: 5 SLTLSLVLLGSSWGCGIPAIKPALSFS--QRIVNGENAVLGSWPWQVSLQDSSGFHFCGG 62
Query: 80 SIVSPQWVITAAHCIANRNIVSTLN-VTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKP 138
S++S WV+TAAHC N+ + V GEYD S Q L++ I HP +++
Sbjct: 63 SLISQSWVVTAAHC----NVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTT- 117
Query: 139 MDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLT-EGGVLSQVLQEV 197
M+ D+ LLK+A Q+ + P+CL E G C T GWGRL+ G V LQ+V
Sbjct: 118 MNNDVTLLKLASPAQYTTRISPVCLASSNEALTEGLTCVTTGWGRLSGVGNVTPAHLQQV 177
Query: 198 NLPILTWEECVAALLTLKRPISGK----TFLCTGFPDGGRDACQGDSGGSLMCRNKKGAW 253
LP++T +C R G + +C G G +CQGDSGG L+C+ K W
Sbjct: 178 ALPLVTVNQC--------RQYWGSSITDSMICAG--GAGASSCQGDSGGPLVCQ-KGNTW 226
Query: 254 TLAGVTSWGL-GCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHI 298
L G+ SWG C NVR +P ++T +SK WI++ I
Sbjct: 227 VLIGIVSWGTKNC------NVR-----APAVYTRVSKFSTWINQVI 261
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 152 bits (384), Expect = 8e-37
Identities = 90/255 (35%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGE 109
SR++GG +PWQVSL+ H CGGS++ +WV+TAAHC + G
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC-----VFRGCGWEGGR 215
Query: 110 YDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQ 169
+ L+ +Q II P + DIAL +A + + + P CLPE +
Sbjct: 216 WLLAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFE 275
Query: 170 FEAGFICTTAGWGRLTE--GGVLSQVLQEVNLPILTWEECVAALLT---LKRPISGKTFL 224
EAG C GWG+++E G + VLQE L I+ E+C L K + + +
Sbjct: 276 VEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTV 335
Query: 225 CTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIF 284
C G+ D G+DACQGDSGG L+C G W G+ SWG+GCGR +G PG++
Sbjct: 336 C-GYNDQGKDACQGDSGGPLVC-ELNGTWVQVGIVSWGIGCGR----------KGYPGVY 383
Query: 285 TDISKVLPWIHEHIQ 299
T++S WI +H++
Sbjct: 384 TEVSFYKKWIIDHLR 398
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 152 bits (384), Expect = 8e-37
Identities = 90/255 (35%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGE 109
SR++GG +PWQVSL+ H CGGS++ +WV+TAAHC + G
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC-----VFRGCGWEGGR 215
Query: 110 YDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQ 169
+ L+ +Q II P + DIAL +A + + + P CLPE +
Sbjct: 216 WLLAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFE 275
Query: 170 FEAGFICTTAGWGRLTE--GGVLSQVLQEVNLPILTWEECVAALLT---LKRPISGKTFL 224
EAG C GWG+++E G + VLQE L I+ E+C L K + + +
Sbjct: 276 VEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTV 335
Query: 225 CTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIF 284
C G+ D G+DACQGDSGG L+C G W G+ SWG+GCGR +G PG++
Sbjct: 336 C-GYNDQGKDACQGDSGGPLVC-ELNGTWVQVGIVSWGIGCGR----------KGYPGVY 383
Query: 285 TDISKVLPWIHEHIQ 299
T++S WI +H++
Sbjct: 384 TEVSFYKKWIIDHLR 398
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 152 bits (384), Expect = 8e-37
Identities = 90/255 (35%), Positives = 130/255 (50%), Gaps = 22/255 (8%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGE 109
SR++GG +PWQVSL+ H CGGS++ +WV+TAAHC + G
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHC-----VFRGCGWEGGR 215
Query: 110 YDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQ 169
+ L+ +Q II P + DIAL +A + + + P CLPE +
Sbjct: 216 WLLAGIGRWDQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEKLFE 275
Query: 170 FEAGFICTTAGWGRLTE--GGVLSQVLQEVNLPILTWEECVAALLT---LKRPISGKTFL 224
EAG C GWG+++E G + VLQE L I+ E+C L K + + +
Sbjct: 276 VEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTRGTV 335
Query: 225 CTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIF 284
C G+ D G+DACQGDSGG L+C G W G+ SWG+GCGR +G PG++
Sbjct: 336 C-GYNDQGKDACQGDSGGPLVC-ELNGTWVQVGIVSWGIGCGR----------KGYPGVY 383
Query: 285 TDISKVLPWIHEHIQ 299
T++S WI +H++
Sbjct: 384 TEVSFYKKWIIDHLR 398
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 152 bits (383), Expect = 1e-36
Identities = 88/256 (34%), Positives = 135/256 (52%), Gaps = 26/256 (10%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGE 109
SRI+GG G++PWQVSL + H+CGGSI++P+W++TAAHC+ + + + + TA
Sbjct: 291 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCV-EKPLNNPWHWTAFA 349
Query: 110 YDLSQT----DPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPE 165
L Q+ G Q +E VI HP++ + K + DIAL+K+ F V P+CLP
Sbjct: 350 GILRQSFMFYGAGYQ---VEKVISHPNYDS-KTKNNDIALMKLQKPLTFNDLVKPVCLPN 405
Query: 166 LREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALL--TLKRPISGKTF 223
+ +C +GWG E G S+VL + ++ + C + + L P
Sbjct: 406 PGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITP----AM 461
Query: 224 LCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGI 283
+C GF G D+CQGDSGG L+ +K W L G TSWG GC + +R PG+
Sbjct: 462 ICAGFLQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYR----------PGV 510
Query: 284 FTDISKVLPWIHEHIQ 299
+ ++ WI+ ++
Sbjct: 511 YGNVMVFTDWIYRQMR 526
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 152 bits (383), Expect = 1e-36
Identities = 88/256 (34%), Positives = 135/256 (52%), Gaps = 26/256 (10%)
Query: 50 SRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGE 109
SRI+GG G++PWQVSL + H+CGGSI++P+W++TAAHC+ + + + + TA
Sbjct: 254 SRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCV-EKPLNNPWHWTAFA 312
Query: 110 YDLSQT----DPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPE 165
L Q+ G Q +E VI HP++ + K + DIAL+K+ F V P+CLP
Sbjct: 313 GILRQSFMFYGAGYQ---VEKVISHPNYDS-KTKNNDIALMKLQKPLTFNDLVKPVCLPN 368
Query: 166 LREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALL--TLKRPISGKTF 223
+ +C +GWG E G S+VL + ++ + C + + L P
Sbjct: 369 PGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITP----AM 424
Query: 224 LCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGI 283
+C GF G D+CQGDSGG L+ +K W L G TSWG GC + +R PG+
Sbjct: 425 ICAGFLQGNVDSCQGDSGGPLV-TSKNNIWWLIGDTSWGSGCAKAYR----------PGV 473
Query: 284 FTDISKVLPWIHEHIQ 299
+ ++ WI+ ++
Sbjct: 474 YGNVMVFTDWIYRQMR 489
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,652,121
Number of Sequences: 37866
Number of extensions: 1052457
Number of successful extensions: 3256
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 213
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1926
Number of HSP's gapped (non-prelim): 558
length of query: 564
length of database: 18,247,518
effective HSP length: 108
effective length of query: 456
effective length of database: 14,157,990
effective search space: 6456043440
effective search space used: 6456043440
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.