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Search of human proteins with 146262005
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|146262005 CTAGE family, member 6 [Homo sapiens]
(777 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|146262005 CTAGE family, member 6 [Homo sapiens] 1562 0.0
gi|56847634 hypothetical protein LOC441294 [Homo sapiens] 1555 0.0
gi|193290160 CTAGE family, member 4 [Homo sapiens] 1500 0.0
gi|224586773 hypothetical protein LOC643854 [Homo sapiens] 1487 0.0
gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens] 1296 0.0
gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens] 1257 0.0
gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens] 1244 0.0
gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens] 1211 0.0
gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isofo... 1140 0.0
gi|122891870 melanoma inhibitory activity family, member 3 [Homo... 242 8e-64
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 80 7e-15
gi|55770834 centromere protein F [Homo sapiens] 79 1e-14
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 78 3e-14
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 78 4e-14
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 78 4e-14
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 77 5e-14
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 77 6e-14
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 76 1e-13
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 75 3e-13
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 75 3e-13
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 75 3e-13
gi|118498356 kinectin 1 isoform a [Homo sapiens] 74 4e-13
gi|33620775 kinectin 1 isoform a [Homo sapiens] 74 4e-13
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 74 4e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 73 9e-13
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 73 9e-13
gi|42794779 myosin 18A isoform b [Homo sapiens] 73 9e-13
gi|28416946 myosin 18A isoform a [Homo sapiens] 73 9e-13
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 72 2e-12
gi|156104908 myosin heavy chain 6 [Homo sapiens] 72 2e-12
>gi|146262005 CTAGE family, member 6 [Homo sapiens]
Length = 777
Score = 1562 bits (4044), Expect = 0.0
Identities = 777/777 (100%), Positives = 777/777 (100%)
Query: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE
Sbjct: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
Query: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR
Sbjct: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
Query: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP
Sbjct: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
Query: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE
Sbjct: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF 777
FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF 777
>gi|56847634 hypothetical protein LOC441294 [Homo sapiens]
Length = 777
Score = 1555 bits (4027), Expect = 0.0
Identities = 773/777 (99%), Positives = 776/777 (99%)
Query: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKG+VSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
TQQ SLQSENIYFESENQKLQQKLKIMTEFYQE+EMKLYRKLTVEENYRIEEEEKLS+VE
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR
Sbjct: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
Query: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP
Sbjct: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
Query: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE
Sbjct: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF 777
FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF 777
>gi|193290160 CTAGE family, member 4 [Homo sapiens]
Length = 777
Score = 1500 bits (3883), Expect = 0.0
Identities = 749/777 (96%), Positives = 757/777 (97%)
Query: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW
Sbjct: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE
Sbjct: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
TQQ SLQSENIYFESENQKLQQKLKIMTEFYQE+EMKLYRKLTVEENYRIEEEEKLS+VE
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EK+SRATE LETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR
Sbjct: 421 EKISRATEGLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREH+P P+PLG+ SSETRAF SPQ
Sbjct: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
Query: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
TLLEDPL LSPVLP GGGRGP PGNPLDHQITNERGEPS DRL DPHRAPSDTGSLSSP
Sbjct: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
Query: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
VEQD +MMFPPPGQSYPDS LPPQREDRFYSNSERLSG AEPRSFKMTSLDKMD SMPSE
Sbjct: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
MESSRNDAKDDLGNLNVPDSSLPAENEATGPG IPPPLAP+ GPLFPVDTRGPFMRRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF 777
FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPY HPRPGFYPNP F
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF 777
>gi|224586773 hypothetical protein LOC643854 [Homo sapiens]
Length = 777
Score = 1487 bits (3850), Expect = 0.0
Identities = 742/777 (95%), Positives = 754/777 (97%)
Query: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPGATPQPYLGLVLEEL RVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW
Sbjct: 1 MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA
Sbjct: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
Query: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
AAEEARSLEATCEKL+RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE
Sbjct: 121 AAEEARSLEATCEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKG+VSE
Sbjct: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSE 240
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLEL+VNSQ
Sbjct: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQ 300
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
WENGANLDDP KGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ
Sbjct: 301 WENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
Query: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
TQQ SLQSENIYFESENQKLQQKLKIMTEFYQE+EMKLYRKLTVEENYRIEEEEKLS+VE
Sbjct: 361 TQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVE 420
Query: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EK+S ATE+LETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR
Sbjct: 421 EKISHATEELETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
Query: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
KENAHNKQKLTE ELKFELLEKDPNALDVSNTAFGREH+P P+PLG+ SSETRAF SPQ
Sbjct: 481 KENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQ 540
Query: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
TLLEDPL LSPVLP GGGRGP PGNPLDHQITNERGEPS DRL DPHRAPSDTGSLSSP
Sbjct: 541 TLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSP 600
Query: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
VEQD +MMFPPPGQSYPDS LPPQREDRFYSNSERLSG AEPRSFKMTSLDKMD SMPSE
Sbjct: 601 VEQDRRMMFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSE 660
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
MESSRNDAKDDLGNLNVPDSSLPAENEATGPG IPPPLAP+ GPLFPVDTRGPFMRRGPP
Sbjct: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPP 720
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF 777
FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPY HPRPGFYPNP F
Sbjct: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF 777
>gi|42740897 CTAGE family, member 5 isoform 1 [Homo sapiens]
Length = 804
Score = 1296 bits (3354), Expect = 0.0
Identities = 649/775 (83%), Positives = 698/775 (90%), Gaps = 2/775 (0%)
Query: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPG TPQPYLGL+LEELRRVVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLW
Sbjct: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGRE+KL LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK
Sbjct: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
Query: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
A E A+SLEATCEKLNRSNSELEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDE
Sbjct: 121 ATE-AQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
SKSLKSQ+AEAK+ K F+M+EER IAIKDALNENSQLQ S KQL Q EAEVWK +VSE
Sbjct: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSE 238
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
LNKQK+TFEDSKVHAEQVLNDKE+HIKTLT L MKD AA+L ED TDDDNLELE+NS+
Sbjct: 239 LNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
ENGA LD+P KGALKKLIHAAKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQ
Sbjct: 299 SENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 358
Query: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
T+Q SLQSEN +FE+ENQKLQQKLK+MTE YQE+EMKL+RKLTVEENYR+E+EEKLSKV+
Sbjct: 359 TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVD 418
Query: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EK+S ATE+LETYRK AKDLEEELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLR
Sbjct: 419 EKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLR 478
Query: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
KENAHN+QKLTETELKFELLEKDP ALDV NTAFGREH+P GP+PLG SSETRAFLSP
Sbjct: 479 KENAHNRQKLTETELKFELLEKDPYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPP 538
Query: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
TLLE PL LSP+LP GGGRG RGPGNPLDHQITNERGE SCDRLTDPHRAPSDTGSLS P
Sbjct: 539 TLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPP 598
Query: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
+QD +MMFPPPGQSYPDSALPPQR+DRF SNS RLSG AE RSF M SLDKMDGSMPSE
Sbjct: 599 WDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSE 658
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
MESSRND KDDLGNLNVPDSSLPAENEATGPGF+PPPLAP+RGPLFPVD RGPF+RRGPP
Sbjct: 659 MESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPP 718
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNP 775
FPPPPPG MFGASR YFPP DFPGPP APFAMRN+YPPRG PPY PRPGF+P P
Sbjct: 719 FPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 773
>gi|42740905 CTAGE family, member 5 isoform 2 [Homo sapiens]
Length = 792
Score = 1257 bits (3252), Expect = 0.0
Identities = 630/754 (83%), Positives = 678/754 (89%), Gaps = 2/754 (0%)
Query: 22 VVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGAT 81
VVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLWRSFRSVRSRLYVGRE+KL
Sbjct: 10 VVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALM 69
Query: 82 LSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSE 141
LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK A E A+SLEATCEKLNRSNSE
Sbjct: 70 LSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATE-AQSLEATCEKLNRSNSE 128
Query: 142 LEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMS 201
LEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDESKSLKSQ+AEAK+ K F+M+
Sbjct: 129 LEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMN 188
Query: 202 EERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLND 261
EER IAIKDALNENSQLQ S KQL Q EAEVWK +VSELNKQK+TFEDSKVHAEQVLND
Sbjct: 189 EERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLND 247
Query: 262 KENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHA 321
KE+HIKTLT L MKD AA+L ED TDDDNLELE+NS+ ENGA LD+P KGALKKLIHA
Sbjct: 248 KESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHA 307
Query: 322 AKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQ 381
AKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQT+Q SLQSEN +FE+ENQKLQ
Sbjct: 308 AKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQ 367
Query: 382 QKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLE 441
QKLK+MTE YQE+EMKL+RKLTVEENYR+E+EEKLSKV+EK+S ATE+LETYRK AKDLE
Sbjct: 368 QKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLE 427
Query: 442 EELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLE 501
EELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLRKENAHN+QKLTETELKFELLE
Sbjct: 428 EELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLE 487
Query: 502 KDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGP 561
KDP ALDV NTAFGREH+P GP+PLG SSETRAFLSP TLLE PL LSP+LP GGGRG
Sbjct: 488 KDPYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGS 547
Query: 562 RGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPPGQSYPDSAL 621
RGPGNPLDHQITNERGE SCDRLTDPHRAPSDTGSLS P +QD +MMFPPPGQSYPDSAL
Sbjct: 548 RGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSAL 607
Query: 622 PPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPDSS 681
PPQR+DRF SNS RLSG AE RSF M SLDKMDGSMPSEMESSRND KDDLGNLNVPDSS
Sbjct: 608 PPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSS 667
Query: 682 LPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRD 741
LPAENEATGPGF+PPPLAP+RGPLFPVD RGPF+RRGPPFPPPPPG MFGASR YFPP D
Sbjct: 668 LPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGD 727
Query: 742 FPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNP 775
FPGPP APFAMRN+YPPRG PPY PRPGF+P P
Sbjct: 728 FPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 761
>gi|42740901 CTAGE family, member 5 isoform 4 [Homo sapiens]
Length = 775
Score = 1244 bits (3220), Expect = 0.0
Identities = 623/746 (83%), Positives = 671/746 (89%), Gaps = 2/746 (0%)
Query: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
MRPD N YGFP ELV+CAAV+GFF VL FLWRSFRSVRSRLYVGRE+KL LSGLIEEK
Sbjct: 1 MRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEK 60
Query: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCL 149
KLLEKFSL+QKEYEGYEVESSL+DASFEK A E A+SLEATCEKLNRSNSELEDEILCL
Sbjct: 61 SKLLEKFSLVQKEYEGYEVESSLKDASFEKEATE-AQSLEATCEKLNRSNSELEDEILCL 119
Query: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
EK+LKEEKSKHS+QDELMADISK IQSLEDESKSLKSQ+AEAK+ K F+M+EER IAI
Sbjct: 120 EKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAI 179
Query: 210 KDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
KDALNENSQLQ S KQL Q EAEVWK +VSELNKQK+TFEDSKVHAEQVLNDKE+HIKTL
Sbjct: 180 KDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTL 238
Query: 270 TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLK 329
T L MKD AA+L ED TDDDNLELE+NS+ ENGA LD+P KGALKKLIHAAKLN SLK
Sbjct: 239 TERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLK 298
Query: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTE 389
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+Q SLQSEN +FE+ENQKLQQKLK+MTE
Sbjct: 299 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTE 358
Query: 390 FYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVH 449
YQE+EMKL+RKLTVEENYR+E+EEKLSKV+EK+S ATE+LETYRK AKDLEEELERT+H
Sbjct: 359 LYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIH 418
Query: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDV 509
YQ Q+IS+EK+ HDNWLAAR AERNL+DLRKENAHN+QKLTETELKFELLEKDP ALDV
Sbjct: 419 SYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDV 478
Query: 510 SNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGPRGPGNPLD 569
NTAFGREH+P GP+PLG SSETRAFLSP TLLE PL LSP+LP GGGRG RGPGNPLD
Sbjct: 479 PNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLD 538
Query: 570 HQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPPGQSYPDSALPPQREDRF 629
HQITNERGE SCDRLTDPHRAPSDTGSLS P +QD +MMFPPPGQSYPDSALPPQR+DRF
Sbjct: 539 HQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRF 598
Query: 630 YSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
SNS RLSG AE RSF M SLDKMDGSMPSEMESSRND KDDLGNLNVPDSSLPAENEAT
Sbjct: 599 CSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEAT 658
Query: 690 GPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
GPGF+PPPLAP+RGPLFPVD RGPF+RRGPPFPPPPPG MFGASR YFPP DFPGPP AP
Sbjct: 659 GPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAP 718
Query: 750 FAMRNIYPPRGLPPYFHPRPGFYPNP 775
FAMRN+YPPRG PPY PRPGF+P P
Sbjct: 719 FAMRNVYPPRGFPPYLPPRPGFFPPP 744
>gi|42740899 CTAGE family, member 5 isoform 3 [Homo sapiens]
Length = 761
Score = 1211 bits (3133), Expect = 0.0
Identities = 616/775 (79%), Positives = 662/775 (85%), Gaps = 45/775 (5%)
Query: 1 MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLW 60
MEEPG TPQPYLGL+LEELRRVVAALPE MRPD N YGFP ELV+CAAV+GFF VL FLW
Sbjct: 1 MEEPGVTPQPYLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLW 60
Query: 61 RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKA 120
RSFRSVRSRLYVGRE+KL LSGLIEEK KLLEKFSL+QKEYEGYEVESSL+DASFEK
Sbjct: 61 RSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKE 120
Query: 121 AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
A E A+SLEATCEKLNRSNSELEDEILCLEK+LKEEKSKHS+QDELMADISK IQSLEDE
Sbjct: 121 ATE-AQSLEATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDE 179
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
SKSLKSQ+AEAK+ K F+M+EER IAIKDALNENSQLQ S KQL Q EAEVWK +VSE
Sbjct: 180 SKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSE 238
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
LNKQK+TFEDSKVHAEQVLNDKE+HIKTLT L MKD AA+L ED TDDDNLELE+NS+
Sbjct: 239 LNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSE 298
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
ENGA LD+P KGALKKLIHAAKLN SLK+LEGERN I IQLSEVDKTKEELTEHIKNLQ
Sbjct: 299 SENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQ 358
Query: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
T+Q SLQSEN +FE+ENQKLQQKLK+MTE YQE+EMKL+RKLTVEENYR+E+EEKLSKV+
Sbjct: 359 TEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVD 418
Query: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
EK+S ATE+LETYRK AKDLEEELERT+H YQ Q+IS+EK+ HDNWLAAR AERNL+DLR
Sbjct: 419 EKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLR 478
Query: 481 KENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQ 540
KENAHN+QKLTETELKFELLEKDP ALDV NTAFG
Sbjct: 479 KENAHNRQKLTETELKFELLEKDPYALDVPNTAFG------------------------- 513
Query: 541 TLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSP 600
RG RGPGNPLDHQITNERGE SCDRLTDPHRAPSDTGSLS P
Sbjct: 514 ------------------RGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPP 555
Query: 601 VEQDCKMMFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSE 660
+QD +MMFPPPGQSYPDSALPPQR+DRF SNS RLSG AE RSF M SLDKMDGSMPSE
Sbjct: 556 WDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSE 615
Query: 661 MESSRNDAKDDLGNLNVPDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPP 720
MESSRND KDDLGNLNVPDSSLPAENEATGPGF+PPPLAP+RGPLFPVD RGPF+RRGPP
Sbjct: 616 MESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPP 675
Query: 721 FPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNP 775
FPPPPPG MFGASR YFPP DFPGPP APFAMRN+YPPRG PPY PRPGF+P P
Sbjct: 676 FPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPP 730
>gi|90819229 cutaneous T-cell lymphoma-associated antigen 1 isoform
1 [Homo sapiens]
Length = 745
Score = 1140 bits (2950), Expect = 0.0
Identities = 581/744 (78%), Positives = 637/744 (85%), Gaps = 4/744 (0%)
Query: 30 MRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEK 89
MRPD +PYGFP ELV+ AAV GFF VL FLWRSFRSV SRLYV RE+K LSGLIEEK
Sbjct: 1 MRPDSHPYGFPWELVIRAAVAGFFAVL-FLWRSFRSVTSRLYVRREKKFAVALSGLIEEK 59
Query: 90 CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCL 149
CKLLEKFSL+QKEYEGYEVESSL++ASFEK A E A+SLEATCEKLNR NSEL EILCL
Sbjct: 60 CKLLEKFSLVQKEYEGYEVESSLKNASFEKEATE-AQSLEATCEKLNRFNSELVHEILCL 118
Query: 150 EKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAI 209
EK+LKEEKSKHS+Q+ELMADISK IQSLEDESKSLKSQ+AEAK+ K F+ +EER I I
Sbjct: 119 EKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEI 178
Query: 210 KDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTL 269
+DA ENS+LQ S KQL Q EAEVWK +VSEL KQK TFEDSKVHAEQVLNDKENHIKTL
Sbjct: 179 QDAWKENSELQESQKQLLQ-EAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTL 237
Query: 270 TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLK 329
T L MKD A+LEED TDDDNLELE+NS+ E+GA LD+P KGALKKLIHAAKLN SLK
Sbjct: 238 TERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLK 297
Query: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTE 389
+LEGERN I IQLSEVDKTKEELTEHIKNLQT+Q SLQSEN +FESENQKLQQKLK+MTE
Sbjct: 298 TLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTE 357
Query: 390 FYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVH 449
YQE+EMKLYRKL VEE R+E+EEKLSKV+E +S ATE+LETYRK AKDL+E E+T+H
Sbjct: 358 LYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLKE-FEKTIH 416
Query: 450 FYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDV 509
FYQK++I +EK+ HDNW AA TAERNL+DLRKENAHN+QKLTE E K +LLEKDP LDV
Sbjct: 417 FYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDV 476
Query: 510 SNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGPRGPGNPLD 569
NTAFGR+H+P GP+PLG SSETRA L P TLLE PL LSP+LP GGGRG RGPGNP D
Sbjct: 477 PNTAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPD 536
Query: 570 HQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPPGQSYPDSALPPQREDRF 629
HQIT ERGE SCDRLTDPHRAPSD G L+ P EQD +MMFPPPGQSYPDSALPPQR+DRF
Sbjct: 537 HQITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRMMFPPPGQSYPDSALPPQRQDRF 596
Query: 630 YSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPDSSLPAENEAT 689
YSN RLSG AE RSF M SLDKMDGSMPSEMESSRND KD+LGNL VPDSSLPAENEAT
Sbjct: 597 YSNCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPDSSLPAENEAT 656
Query: 690 GPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAP 749
GPGF+PPPLAP+RG LFPVDTRGPF+RRGPPFPPPPPGT+FGAS YF PRD PGPP AP
Sbjct: 657 GPGFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAP 716
Query: 750 FAMRNIYPPRGLPPYFHPRPGFYP 773
FAMRN+Y PRG PY PRP F+P
Sbjct: 717 FAMRNVYLPRGFLPYRPPRPAFFP 740
>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
sapiens]
Length = 1907
Score = 242 bits (618), Expect = 8e-64
Identities = 217/789 (27%), Positives = 368/789 (46%), Gaps = 103/789 (13%)
Query: 20 RRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLG 79
+ +VA LP+ ++P + YG P + V A +G +FLWR+ V+ R+Y EQ++
Sbjct: 1158 KSLVATLPDDVQPGPDFYGLPWKPVFITAFLGIASFAIFLWRTVLVVKDRVYQVTEQQIS 1217
Query: 80 ATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAA-AEEARSLEATCEKLNRS 138
L +++E +L++K S +++ + E + +++ + ++EA + + L ++
Sbjct: 1218 EKLKTIMKENTELVQKLSNYEQKIK--ESKKHVQETRKQNMILSDEAIKYKDKIKTLEKN 1275
Query: 139 NSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
L+D L L+ E+ ++ + +L+++ KSI+ L+D S+ +E +I
Sbjct: 1276 QEILDDTAKNLRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEVQIALNEA 1335
Query: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQV 258
K+SEE+ EN++L+ +QL QQE E W +EL++Q +FE S+ E
Sbjct: 1336 KLSEEKVKSECHRVQEENARLKKKKEQL-QQEIEDWSKLHAELSEQIKSFEKSQKDLEVA 1394
Query: 259 LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKL 318
L K+++I LT + + E + + + + + E G + ++ +K +K++
Sbjct: 1395 LTHKDDNINALTNCITQLNLLECESESEGQNKGGNDSDELANGEVGGDRNEKMKNQIKQM 1454
Query: 319 IHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQ 378
+ ++ ++ +E + + ++L TK L + +K L+ + SLQ+ E E +
Sbjct: 1455 MDVSRTQTAISVVEEDLKLLQLKLRASVSTKCNLEDQVKKLEDDRNSLQAAKAGLEDECK 1514
Query: 379 KLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAK 438
L+QK++I+ E YQ+ EM L +KL+ EE R E E +LS +EK A E+++TY++ +
Sbjct: 1515 TLRQKVEILNELYQQKEMALQKKLSQEEYERQEREHRLSAADEKAVSAAEEVKTYKRRIE 1574
Query: 439 DLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFE 498
++E+EL++T ++ Q+ ++EK+ H+NWL AR AER +++ ++E A+ + KL E K
Sbjct: 1575 EMEDELQKTERSFKNQIATHEKKAHENWLKARAAERAIAEEKREAANLRHKLLELTQKMA 1634
Query: 499 LLEKDPNALDVSNTAFGREHAPNGP--APLGQRSSETRAFLSPQTLLEDPLGLSPVLPEG 556
+L+++P + G+ + N P PL Q S G SPV G
Sbjct: 1635 MLQEEP---VIVKPMPGKPNTQNPPRRGPLSQNGS---------------FGPSPV--SG 1674
Query: 557 GGRGP----RGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPP 612
G P P PL + N R P S+ GS+ P+ P P
Sbjct: 1675 GECSPPLTVEPPVRPLSATL-NRRDMPR-----------SEFGSVDGPL--------PHP 1714
Query: 613 GQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDL 672
S S P S S+ SG+A M S + GS P+ + D
Sbjct: 1715 RWSAEASGKP--------SPSDPGSGTAT----MMNSSSR--GSSPTRVL--------DE 1752
Query: 673 GNLNV------PDSSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRR--GPPFPP- 723
G +N+ P +P + G G +PPP+ GP P GPF R PPF P
Sbjct: 1753 GKVNMAPKGPPPFPGVPLMSTPMG-GPVPPPIR--YGP--PPQLCGPFGPRPLPPPFGPG 1807
Query: 724 --PP-------PGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPR-------GLPPYFHP 767
PP PG G PR F P HAPF PR LPP H
Sbjct: 1808 MRPPLGLREFAPGVPPGRRDLPLHPRGFL-PGHAPFRPLGSLGPREYFIPGTRLPPPTHG 1866
Query: 768 RPGFYPNPA 776
+ P PA
Sbjct: 1867 PQEYPPPPA 1875
Score = 31.2 bits (69), Expect = 3.8
Identities = 36/163 (22%), Positives = 60/163 (36%), Gaps = 24/163 (14%)
Query: 314 ALKKLIHAAKLNVSL-KSLEGERNHIIIQLSEVDKTKEELTE----------HIKNLQTQ 362
A++K + + N L K E E + E D E TE H + +Q
Sbjct: 157 AVEKTLQDMEKNPELSKEREPEPEPVEANSEESDSVFSENTEDLQEQFTTQKHHSHANSQ 216
Query: 363 QESLQSENIYFESENQKLQQKLKIMTE-----------FYQEDEMKLYRKLTVEENYRIE 411
Q E FES + LQ KLK+ ++D++ Y+ L ++ ++
Sbjct: 217 ANHAQGEQASFESFEEMLQDKLKVPESENNKTSNSSQVSNEQDKIDAYKLL--KKEMTLD 274
Query: 412 EEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQ 454
+ K + L E L D +EEL+ + K+
Sbjct: 275 LKTKFGSTADALVSDDETTRLVTSLEDDFDEELDTEYYAVGKE 317
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 80.1 bits (196), Expect = 7e-15
Identities = 88/395 (22%), Positives = 177/395 (44%), Gaps = 44/395 (11%)
Query: 74 REQKL---GATLSGLIEEKCKLLEKFSLIQKEYEGYEV--ESSLEDASFEKAAAEEARSL 128
+EQK+ T++ L E + +L ++ +QK + E+ + + + A+ R +
Sbjct: 1110 KEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLM 1169
Query: 129 EATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQI 188
+ +KL N+++ED LE+++K +K K E + + S+Q E+++ +K +
Sbjct: 1170 KELNQKLTNKNNKIED----LEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLL 1225
Query: 189 AEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHK---QLFQQEAEVWKGEVSELNKQK 245
+ K + K A ++ LQ S K + QQ+ EV+K +++E
Sbjct: 1226 VKTK-----------KELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAE----- 1269
Query: 246 ITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGA 305
IT E K+H E + E H +TL+ + + + L+E+ + V S++E
Sbjct: 1270 ITSEKHKIH-EHLKTSAEQHQRTLSAY----QQRVTALQEECRAAKAEQATVTSEFE--- 1321
Query: 306 NLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQES 365
+ + LK+ + + + + ER H+ + +D+ K +L + NLQ
Sbjct: 1322 SYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEML---IDQLKIKLQDSQNNLQINVSE 1378
Query: 366 LQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKL-TVEENYRIEEEEKLSKVEEKLS 424
LQ+ +SE+ L ++ M + E +L KL +++ + + E V + S
Sbjct: 1379 LQT----LQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTS 1434
Query: 425 RATEQLETYRKLAKDLEEELERTVHFYQKQVISYE 459
+ ++R + L+EE +TV Q+Q+ E
Sbjct: 1435 QNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKME 1469
Score = 72.8 bits (177), Expect = 1e-12
Identities = 103/452 (22%), Positives = 193/452 (42%), Gaps = 70/452 (15%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKL 135
Q +G +L+ + EEKC L Q++ + E+E + K EE+ CE+L
Sbjct: 784 QAVGESLAKINEEKCNLA-----FQRDEKVLELEKEI------KCLQEES---VVQCEEL 829
Query: 136 NRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC 195
+ E E + L K+L+E +S+ + ++ + + E+++L Q+ E C
Sbjct: 830 KSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTC 889
Query: 196 KTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHA 255
++ E+ IK+ +EN + K+L + AE+ I +DS +
Sbjct: 890 SKSEIHNEKEKCFIKE--HENLKPLLEQKELRDRRAEL------------ILLKDSLAKS 935
Query: 256 EQVLNDKENHIKTLTGHLPMMKDQ-------------AAVLEEDTTDDDNLELE-VNSQW 301
V ND + +K L + ++ + AV + D E + V +
Sbjct: 936 PSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEEL 995
Query: 302 ENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTK--------EELT 353
E+ + D L +++ LI A+ S K+L E QL +V+K + E+LT
Sbjct: 996 ESLRSEKDQLSASMRDLIQGAE---SYKNLLLEYEKQSEQL-DVEKERANNFEHRIEDLT 1051
Query: 354 EHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEE 413
++N Q E++ S+N + + LQ K++ E + K V++ E+
Sbjct: 1052 RQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQR---AKAMVDKELEAEKL 1108
Query: 414 EKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAE 473
+K K++E + E E +L K+ +++L++T+ Q + K+ A +T
Sbjct: 1109 QKEQKIKEHATTVNELEELQVQLQKE-KKQLQKTM-----QELELVKKD-----AQQTTL 1157
Query: 474 RN--LSDLRKENAHNKQKLTETELKFELLEKD 503
N ++D + QKLT K E LE++
Sbjct: 1158 MNMEIADYERLMKELNQKLTNKNNKIEDLEQE 1189
Score = 63.2 bits (152), Expect = 9e-10
Identities = 89/446 (19%), Positives = 193/446 (43%), Gaps = 64/446 (14%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKL 135
++L ++ L EEK + K +E + + + E E+ E + +E T +
Sbjct: 583 KELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCERE----ERLILELGKKVEQTIQY- 637
Query: 136 NRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC 195
NSELE ++ L L+E + Q D+ + + ++ L ++ + L +++
Sbjct: 638 ---NSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEV------- 687
Query: 196 KTFKMSEERRAIAIKDALNENSQLQTSHKQ--------LFQQEAEVWKGEVSELNKQKIT 247
K EN++L + KQ L Q+E + K +++L K+
Sbjct: 688 --------------KSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQL 733
Query: 248 FEDSKVHAEQVL-NDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGAN 306
+ + + ++L N++ + T +K+ + + ED+ + D + + + + E+ A
Sbjct: 734 MVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGSEVSEDSEEKDVVNV-LQAVGESLAK 792
Query: 307 L-DDPLKGALKKLIHAAKLNVSLKSLEGER----NHIIIQLSEVDKTKEELTEHIKNLQT 361
+ ++ A ++ +L +K L+ E + L + ++ K L + ++ +Q+
Sbjct: 793 INEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQS 852
Query: 362 QQESLQSENIYFESENQKLQ---QKLKIMTEFYQE--DEMKLYRKLTVEENYRIEEEEKL 416
++E+LQS+ + ++ N+K + Q L I E + + +++ + +E I+E E L
Sbjct: 853 EKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHNE---KEKCFIKEHENL 909
Query: 417 SKV---EEKLSRATEQLETYRKLAKDLE---------EELERTVHFYQKQVISYEKRGHD 464
+ +E R E + LAK +ELE + +K+ E++ +
Sbjct: 910 KPLLEQKELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINK 969
Query: 465 NWLAARTAERNLSDLRKENAHNKQKL 490
L A A++ L RKE K++L
Sbjct: 970 IKLVAVKAKKELDSSRKETQTVKEEL 995
Score = 54.7 bits (130), Expect = 3e-07
Identities = 91/456 (19%), Positives = 194/456 (42%), Gaps = 51/456 (11%)
Query: 91 KLLEKFSLIQKEYEGY--EVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILC 148
+LL+ ++ Q+E + ++E+S ++ E E + E ++ S ++ + C
Sbjct: 240 ELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELK--ENLVKQCEASEKNIQKKYEC 297
Query: 149 LEKDLKEEKSKHSQQDELMAD-----------ISKSIQSLEDESKSLKSQ---IAEAKII 194
++L++ S +Q +++ + +++ ++ LED K L+SQ + +
Sbjct: 298 ELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTY 357
Query: 195 CKTFKMSEERRAIAIKDAL---NENSQLQTSHKQLFQQEA----EVWKGEVSELNKQKIT 247
K+ E A IKD E+ + + + L ++E E K E++ LNKQ
Sbjct: 358 MNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCY 417
Query: 248 FEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANL 307
+ H +V + KE H K ++ + L + + L E+ E NL
Sbjct: 418 TVEQ--HNREVQSLKEQHQKEIS------ELNETFLSDSEKEKLTLMFEIQGLKEQCENL 469
Query: 308 DDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKE-----ELTEHIKNLQTQ 362
+ A+ ++ L++ GE I Q E K ++ EL + ++ T+
Sbjct: 470 QQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTE 529
Query: 363 QESLQSENIYFESENQKLQQKLKIMTEFYQEDEMK-LYRKLTVEENYRIEEEEKLSKVEE 421
+++L + EN+KL + +++ E E+ +K L K V + + L ++E
Sbjct: 530 KDALLETVNRLQGENEKLLSQQELVPEL--ENTIKNLQEKNGVYLLSLSQRDTMLKELEG 587
Query: 422 KLSRATEQLETYRKLAKDLEEELE---RTVHFYQKQVISYEKRGHDNWLAARTAERNLSD 478
K++ TE+ + + K+ EE++ + ++ ++ K+ E+ +++
Sbjct: 588 KINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNE 647
Query: 479 LR-------KENAHNKQKLTETELKFELLEKDPNAL 507
L KE N QKL + ++ ++L +D L
Sbjct: 648 LTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVL 683
Score = 48.5 bits (114), Expect = 2e-05
Identities = 61/300 (20%), Positives = 132/300 (44%), Gaps = 24/300 (8%)
Query: 149 LEKDLKEEKSKHSQQDELMADISKS-IQSLEDESKSLKSQIAEAKIICKTFKMSEERRAI 207
LE KE+ K +++ ++ +KS LE E + L+S+ ++E A+
Sbjct: 22 LETLPKEDLIKFAKKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTGDIIKALTERLDAL 81
Query: 208 AIKDALNENSQLQTSHKQL-FQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHI 266
++ A E L + + +QE E ++ + +K+ E S ++ + + + +N +
Sbjct: 82 LLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKE---LEQSHINYVKEIENLKNEL 138
Query: 267 KTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNV 326
+ + A L++ + N +LE++ Q + N +D +K KL
Sbjct: 139 MAVRSKY---SEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVK----------KLQE 185
Query: 327 SLKSLE-GERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLK 385
++ + G I+ ++D T +E E + LQ +++ + +++ LQ++L
Sbjct: 186 EIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQN---IIEANSQHYQKNINSLQEELL 242
Query: 386 IMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELE 445
+ +QE+ +L ++ E KL++++E L + E E + + K E ELE
Sbjct: 243 QLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASE--KNIQKKYECELE 300
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 79.3 bits (194), Expect = 1e-14
Identities = 104/456 (22%), Positives = 201/456 (44%), Gaps = 50/456 (10%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEK--------AAAEEARSLEATCEKLN 136
L++E L + S + +YE V +LE A EK + EE L EKL
Sbjct: 2068 LVKESESLQARLS--ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLR 2125
Query: 137 RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICK 196
E + L + + LKE + ++ + + ++ + +Q E+ + + +K +
Sbjct: 2126 VRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVE 2185
Query: 197 TFKMSEERRAIAIK----DALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFE--- 249
T K E A ++K D + S+ + KQ+ +++ G++SEL+K +F+
Sbjct: 2186 TLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQ-----GQLSELDKLLSSFKSLL 2240
Query: 250 DSKVHAE-QVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLD 308
+ K AE Q+ + + ++ L L + + A L D E+ E +LD
Sbjct: 2241 EEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQ--------EIMKATEQ--SLD 2290
Query: 309 DPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQS 368
P++ + KL L++ E ++ ++ QL E + + L ++NL+ + E ++
Sbjct: 2291 PPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIART 2350
Query: 369 --ENIYFESENQK-----LQQKLKIMTEFYQEDEMKLYRKLTVEENYRIE---EEEKLSK 418
E+ E+EN K L+ K++ MT+ + E+ + + +EN E E+E++S+
Sbjct: 2351 NQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISE 2410
Query: 419 VEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRG---HDNWLAARTAERN 475
+E S L+ + ++E+ + Q Q+ +R H++ A + E+N
Sbjct: 2411 LEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQN 2470
Query: 476 LSD----LRKENAHNKQKLTETELKFELLEKDPNAL 507
LS L E A Q L E + + +L+ N L
Sbjct: 2471 LSSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGL 2506
Score = 60.1 bits (144), Expect = 8e-09
Identities = 87/428 (20%), Positives = 188/428 (43%), Gaps = 65/428 (15%)
Query: 128 LEATCEKLNRSNSELEDEILCLE------KDLKEEKSKHSQQDELMADISKSIQSLEDES 181
+E +KL+++ E + + LE ++LKEEK+ S ++ K + +E E
Sbjct: 581 IEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWK---SENEKLLTQMESEK 637
Query: 182 KSLKSQIAEAKIICKTFKMSE----ERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGE 237
++L+S+I + KT ++ ER D N + +++ H L + EV +
Sbjct: 638 ENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQK 697
Query: 238 VSELN-KQKITFEDSKVHAEQVLNDKENHIKT--LTGHLPMMKDQAAVLEEDTTDDDNLE 294
++ + +QK F D K H +++ N +KT LTG + ++ + +L + D D
Sbjct: 698 LAYMELQQKAEFSDQK-HQKEIEN---MCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCY 753
Query: 295 LEVNSQWENGANLDDPLKGALKKLI-------------HAAKLNVSLKSLEGERNHIIIQ 341
++++++E+ L D LK L+ ++ S ++ GE+ + +
Sbjct: 754 QDLHAEYES---LRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSE 810
Query: 342 LSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRK 401
SE ++ ++ LQ + +SL+ + N LQ++ + + + E E L +
Sbjct: 811 RSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKA 870
Query: 402 LTVEENYRIEEEEKLSKVEEKLSR----ATEQLETYRKLAKDLE-------------EEL 444
+ +++ E +++SK++E S E L K+L+ +EL
Sbjct: 871 EQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQEL 930
Query: 445 ERTVHFYQ---------KQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQ-KLTETE 494
+++ H + + +S EK+ + ++ +R + +L +EN K+ + +
Sbjct: 931 KKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLN--KREIEELTQENGTLKEINASLNQ 988
Query: 495 LKFELLEK 502
K L++K
Sbjct: 989 EKMNLIQK 996
Score = 59.7 bits (143), Expect = 1e-08
Identities = 91/436 (20%), Positives = 184/436 (42%), Gaps = 54/436 (12%)
Query: 72 VGREQKLGATLSGLIE-------EKCKLLEKFSLIQKEYEGYEVESSLED-----ASFEK 119
VG +K + LS +E E + +E + + E + +SS ED A
Sbjct: 1832 VGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVND 1891
Query: 120 AAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED 179
+ E +E ++ + +E E L LE DL+ +++ ++ + K I LE+
Sbjct: 1892 SWKERFLDVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEE 1951
Query: 180 ESKSLKSQIAEAKIICKTFKMSEERRAI-AIKDALNENSQLQTSHKQLFQQEAEVWKGEV 238
E + S+ + + T MS++ A+ + + + E +Q SH+ +V + EV
Sbjct: 1952 ELSVVTSERNQLRGELDT--MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEV 2009
Query: 239 SELNKQKITFED-------SKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEED----T 287
E + T K H ++ L E + L+ +++Q A L ++
Sbjct: 2010 KEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLV 2069
Query: 288 TDDDNLELEVNSQWENGANLDDPLKGAL-------------KKLIH-----AAKLNVSLK 329
+ ++L+ ++ N+ L+ AL ++ +H KL V ++
Sbjct: 2070 KESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIE 2129
Query: 330 SLEGERNHIIIQLSEVDKTKEELTEHIKNL--QTQQESLQSENIYFESENQK-----LQQ 382
+ E ++ HI +L E ++ + L + ++NL + Q E + ++EN K L+
Sbjct: 2130 ADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKT 2189
Query: 383 KLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEK---LSKVEEKLSRATEQLETYRKLAKD 439
+++ M + E+ L + +EN + +EK LS++++ LS LE +
Sbjct: 2190 QIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQ 2249
Query: 440 LEEELERTVHFYQKQV 455
++EE + V Q Q+
Sbjct: 2250 IKEESKTAVEMLQNQL 2265
Score = 58.9 bits (141), Expect = 2e-08
Identities = 88/403 (21%), Positives = 184/403 (45%), Gaps = 48/403 (11%)
Query: 78 LGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNR 137
L ++++GLI+E +K L +K+ E +++ ++D ++ + +E +
Sbjct: 2499 LQSSVNGLIQEVEDGKQK--LEKKDEEISRLKNQIQD---QEQLVSKLSQVEGEHQLWKE 2553
Query: 138 SNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE---SKSLKSQIAEA--K 192
N EL + + LE+ ++ +SK++ + + + S ++LE+E +K K E K
Sbjct: 2554 QNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNK 2613
Query: 193 IICKTFKMSEERRAIAIKDA-----LNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKIT 247
+ K ++ E +A K A L+ QL +E + K ++ EL +
Sbjct: 2614 MTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSE 2673
Query: 248 FEDSK--VHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGA 305
+ S +H +QV +KE ++ + L E L L+ N Q+E
Sbjct: 2674 LKKSLDCMHKDQV--EKEGKVREEIAEYQLR------LHEAEKKHQALLLDTNKQYEVEI 2725
Query: 306 NLDDPLKGALKKLIHAAKLNVSL-KSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQE 364
+ ++ + + KL + L KS + E N+ + K ++ E +K +T+ +
Sbjct: 2726 QTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSL-------KATTQILEELK--KTKMD 2776
Query: 365 SLQSENIYFESENQKLQQKLKIMTEFYQ--EDEMKLYRKLTVEENYRIEEEEKL-----S 417
+L+ N + EN++ Q K+K++ + + E+E ++ +K + + +E++K +
Sbjct: 2777 NLKYVN-QLKKENERAQGKMKLLIKSCKQLEEEKEILQK-ELSQLQAAQEKQKTGTVMDT 2834
Query: 418 KVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEK 460
KV+E + E ET + K+ +E L++ Y +IS+EK
Sbjct: 2835 KVDELTTEIKELKETLEEKTKEADEYLDK----YCSLLISHEK 2873
Score = 55.8 bits (133), Expect = 1e-07
Identities = 92/448 (20%), Positives = 188/448 (41%), Gaps = 71/448 (15%)
Query: 84 GLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELE 143
G + E KLL F + +E E E++ E + E L EL
Sbjct: 2224 GQLSELDKLLSSFKSLLEEKEQAEIQIKEES--------------KTAVEMLQNQLKELN 2269
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSE- 202
+ + L D + K+ D + + + S+E L++ E K +C ++ E
Sbjct: 2270 EAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEAD--EKKQLCVLQQLKES 2327
Query: 203 ERRAIAIK---DALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKI-----TFEDSKVH 254
E A +K + L ++ ++++ EAE KGEV L K KI + ++
Sbjct: 2328 EHHADLLKGRVENLERELEIARTNQEHAALEAENSKGEVETL-KAKIEGMTQSLRGLELD 2386
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL----ELEVNSQWENGANLDDP 310
+ ++KEN LT L +++ + LE + +N+ E E E + +
Sbjct: 2387 VVTIRSEKEN----LTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEM 2442
Query: 311 LKGALKKL------IH-------AAKLNVS-------------LKSLEGERNHIIIQLSE 344
L+ LK+L +H A + N+S L+ L+ +N+ I+ S
Sbjct: 2443 LQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNNYIVLQSS 2502
Query: 345 VDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTV 404
V+ +E+ + + L+ + E + + + Q + + ++ E E +L+++ +
Sbjct: 2503 VNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQV------EGEHQLWKEQNL 2556
Query: 405 E-ENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGH 463
E N +E E+K+ ++ K + + LE + K+LE ELE T + +S+ ++ +
Sbjct: 2557 ELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELT----KMDKMSFVEKVN 2612
Query: 464 DNWLAARTAERNLSDLRKENAHNKQKLT 491
+R + ++ ++ A +++L+
Sbjct: 2613 KMTAKETELQREMHEMAQKTAELQEELS 2640
Score = 51.6 bits (122), Expect = 3e-06
Identities = 93/456 (20%), Positives = 191/456 (41%), Gaps = 64/456 (14%)
Query: 85 LIEEKCKLLEKFSLIQK-EYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELE 143
L + K +L+EK ++ K E + + AS + A E+ L+ E L+ E
Sbjct: 322 LEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQ--KLKKLTEDLSCQRQNAE 379
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFK---M 200
LE+ +KE++ + Q+EL +S Q+L+ E +K+++ + K
Sbjct: 380 SARCSLEQKIKEKEKEF--QEELSRQ-QRSFQTLDQECIQMKARLTQELQQAKNMHNVLQ 436
Query: 201 SEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKV------- 253
+E + ++K L N L+ ++L + E ++ E N+ + + E+ K
Sbjct: 437 AELDKLTSVKQQLENN--LEEFKQKLCRAEQAFQASQIKE-NELRRSMEEMKKENNLLKS 493
Query: 254 HAEQVLNDK---ENHIKTLTGHLPMMKDQAAVLEEDTTDDD----NLELEVNSQWENGAN 306
H+EQ + E +K + L ++ A ++ T + +L+ ++N Q EN
Sbjct: 494 HSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQ-ENSLT 552
Query: 307 LDDPLKGALKKLIHAAKLNVSLKSLEGERN----------HIIIQ----LSEVDKTKEEL 352
L+ KL +++ LE +R+ H I Q LS+ +K + L
Sbjct: 553 LE--------------KLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Query: 353 TEHIKNLQTQQESLQSENIYF---ESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYR 409
++ + + E L+ E F +SEN+KL +++ E Q L L ++
Sbjct: 599 LSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKS 658
Query: 410 IEEEEKLSKVEEKLSRATEQLETYRKL--AKDLEEELERTVHFYQKQVISYEKRGHDNWL 467
E E++ +E + ++ + +K +E E ++ + +Q + + H +
Sbjct: 659 HEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEI 718
Query: 468 AARTAERNLSDLRKENAHNKQKLTETELKFELLEKD 503
+ + + E+ +K +L L E+++KD
Sbjct: 719 ENMCLKTSQLTGQVEDLEHKLQL----LSNEIMDKD 750
Score = 51.6 bits (122), Expect = 3e-06
Identities = 85/381 (22%), Positives = 161/381 (42%), Gaps = 49/381 (12%)
Query: 107 EVESSLEDASFE-KAAAEEARSLEATCEKLNRSNSELED---EILCLEKDLKEEKSKHSQ 162
E S+LE+ E + ++ + +A ++L +SN LED E+ L + L EK + S
Sbjct: 901 ETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMS- 959
Query: 163 QDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTS 222
+++ + I+ L E+ +LK I +LN+
Sbjct: 960 --SIISLNKREIEELTQENGTLKE----------------------INASLNQEKMNLIQ 995
Query: 223 HKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAV 282
+ F + + +SEL+ Q ++ K+ Q + N + L+ K +AA
Sbjct: 996 KSESFANYIDEREKSISELSDQ---YKQEKLILLQRCEETGNAYEDLS-----QKYKAA- 1046
Query: 283 LEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQL 342
+E + + L E S EN N + LK A K + L E +++++L
Sbjct: 1047 -QEKNSKLECLLNECTSLCENRKNELEQLKEAFAK--EHQEFLTKLAFAEERNQNLMLEL 1103
Query: 343 SEVDKT-KEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRK 401
V + + E+T++ N +++ L+ E + + E K+Q K + + QE+E +
Sbjct: 1104 ETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQ---KEVNDLLQENEQLMKVM 1160
Query: 402 LTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKR 461
T E +E E + V+E R +E+ + K DLE + E ++ Y Q++ E
Sbjct: 1161 KTKHECQNLESEPIRNSVKE---RESERNQCNFKPQMDLEVK-EISLDSYNAQLVQLEAM 1216
Query: 462 GHDNWLAARTAERNLSDLRKE 482
+ L + +E+ L+ E
Sbjct: 1217 LRNKELKLQESEKEKECLQHE 1237
Score = 50.8 bits (120), Expect = 5e-06
Identities = 73/367 (19%), Positives = 149/367 (40%), Gaps = 37/367 (10%)
Query: 138 SNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKT 197
S S+ ED K+++E K ++ L A K+ Q+L + + + IA +
Sbjct: 160 SGSKYEDLKEKYNKEVEERKRLEAEVKALQA--KKASQTLPQATMNHRD-IARHQASSSV 216
Query: 198 FKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQ 257
F +E+ L+ NSQ + A + GE E+ + T + K A
Sbjct: 217 FSWQQEKTP----SHLSSNSQRTPIRRDF---SASYFSGE-QEVTPSRSTLQIGKRDANS 268
Query: 258 VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKK 317
D + P + DQ ++ + N ELE+ Q + +KG + K
Sbjct: 269 SFFDNSSS--------PHLLDQLKAQNQELRNKIN-ELELRLQGH-----EKEMKGQVNK 314
Query: 318 L----IHAAKLNVSL----KSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSE 369
+ K V L K L R+ ++ ++ D+ + T + L+ E L +
Sbjct: 315 FQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQ 374
Query: 370 NIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQ 429
ES L+QK+K + +QE+ + R + I+ + +L++ ++
Sbjct: 375 RQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNV 434
Query: 430 LETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKEN----AH 485
L+ ++++LE + +++++ E+ + + R++ +++KEN +H
Sbjct: 435 LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSH 494
Query: 486 NKQKLTE 492
++QK E
Sbjct: 495 SEQKARE 501
Score = 48.5 bits (114), Expect = 2e-05
Identities = 88/439 (20%), Positives = 178/439 (40%), Gaps = 62/439 (14%)
Query: 126 RSLEATCEKLNRSNSELED----------EILCLEKDLKEEKSKHSQQDELMADISKSIQ 175
+ +E C K ++ ++ED EI+ ++ ++ +++ +L+ S+
Sbjct: 716 KEIENMCLKTSQLTGQVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLV 775
Query: 176 SLEDESKSLKSQIAE-------AKIICKTFKMSEERRAIAIK-DALNENSQLQTSHKQLF 227
+ ED +SL + + A II + M ER ++ D +NS + +
Sbjct: 776 TNEDHQRSLLAFDQQPAMHHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSL 835
Query: 228 QQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDT 287
+ E K S+L KQ K E+ L E ++ + + L+EDT
Sbjct: 836 EFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAET---SQRISKLQEDT 892
Query: 288 TDDDNLELEVNSQWENGAN----LDDPLKGALKKLIHAAKLNVSLK-------------S 330
+ N+ E S EN L+D ++ ++ K N L+ S
Sbjct: 893 SAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLS 952
Query: 331 LEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSE--NIYFESEN-----QKLQQK 383
LE + II L++ + EELT+ L+ SL E N+ +SE+ + ++
Sbjct: 953 LEKKEMSSIISLNK--REIEELTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKS 1010
Query: 384 LKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEE 443
+ +++ Y+++++ L ++ N + +K +EK S+ L L ++ + E
Sbjct: 1011 ISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNE 1070
Query: 444 LERTVHFYQKQVISY-------EKRGHDNWLAARTAERNLSDLRKENAHN--------KQ 488
LE+ + K+ + E+R + L T ++ L +N +N KQ
Sbjct: 1071 LEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQ 1130
Query: 489 KLTETELKFELLEKDPNAL 507
++ + + ++K+ N L
Sbjct: 1131 EIMTLKEEQNKMQKEVNDL 1149
Score = 44.7 bits (104), Expect = 3e-04
Identities = 75/363 (20%), Positives = 146/363 (40%), Gaps = 87/363 (23%)
Query: 71 YVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEA 130
+V + K+ A + L E ++ +K + +Q+E G + + E + EE +S +
Sbjct: 2607 FVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGE----LQLLLEEIKSSKD 2662
Query: 131 TCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAE 190
++L NSEL+ + C+ KD E++ K ++ +IAE
Sbjct: 2663 QLKELTLENSELKKSLDCMHKDQVEKEGK------------------------VREEIAE 2698
Query: 191 AKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFED 250
++ + + ++ +A+ + ++QT ++L +E L+ QK+ +
Sbjct: 2699 YQL--RLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKE--------ECLSSQKLEIDL 2748
Query: 251 SKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEE-DTTDDDNLELEVNSQWENGANLDD 309
K E++ N +K +LEE T DNL+ + EN +
Sbjct: 2749 LKSSKEELNNS--------------LKATTQILEELKKTKMDNLKYVNQLKKEN-----E 2789
Query: 310 PLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSE 369
+G +K LI + K ++++ KE L + + LQ QE Q
Sbjct: 2790 RAQGKMKLLIKSCK--------------------QLEEEKEILQKELSQLQAAQEK-QKT 2828
Query: 370 NIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQ 429
+++ +L ++K + E +E T E + +++ L EKL +A E
Sbjct: 2829 GTVMDTKVDELTTEIKELKETLEEK--------TKEADEYLDKYCSLLISHEKLEKAKEM 2880
Query: 430 LET 432
LET
Sbjct: 2881 LET 2883
Score = 39.3 bits (90), Expect = 0.014
Identities = 81/387 (20%), Positives = 151/387 (39%), Gaps = 40/387 (10%)
Query: 141 ELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED---ESKSLKSQIAEAKIICKT 197
ELE + L+K KE++ + Q D L A + K Q +E+ E +LK + IC++
Sbjct: 22 ELEGQ---LDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKRENQRLMEICES 78
Query: 198 FKMSEER--RAIAIKDA-LN-ENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKV 253
+ ++++ + +K++ +N + QL + KQ+ + E E+ K SEL + + +
Sbjct: 79 LEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQEL-KRCKSELERS----QQAAQ 133
Query: 254 HAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWE------NGANL 307
A+ LN K T L + + ED + N E+E + E
Sbjct: 134 SADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEERKRLEAEVKALQAKKA 193
Query: 308 DDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKT--------------KEELT 353
L A A+ S ++ LS + ++E+T
Sbjct: 194 SQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASYFSGEQEVT 253
Query: 354 EHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEE 413
LQ + S + + S + L +LK + + +L +L E +
Sbjct: 254 PSRSTLQIGKRDANS-SFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQV 312
Query: 414 EKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAE 473
K +++ +L +A +L K+ +EL RT Y + Y + L T +
Sbjct: 313 NKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKY--TALEQKLKKLTED 370
Query: 474 RNLSDLRKENAH--NKQKLTETELKFE 498
+ E+A +QK+ E E +F+
Sbjct: 371 LSCQRQNAESARCSLEQKIKEKEKEFQ 397
Score = 35.4 bits (80), Expect = 0.20
Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 21/138 (15%)
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYF 373
AL+K+ +L L L+ E+ QL ++ ++ + ++N +T+ +L+ EN
Sbjct: 16 ALQKI---QELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTEGTNLKREN--- 69
Query: 374 ESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLS-------KVEEKLSRA 426
Q+L + E ++ + K+ +L V+E+ +E +L+ K+E++L R
Sbjct: 70 --------QRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRC 121
Query: 427 TEQLETYRKLAKDLEEEL 444
+LE ++ A+ + L
Sbjct: 122 KSELERSQQAAQSADVSL 139
Score = 35.4 bits (80), Expect = 0.20
Identities = 95/461 (20%), Positives = 182/461 (39%), Gaps = 88/461 (19%)
Query: 107 EVESSLEDASFEKAAAEEAR--SLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQD 164
E ES +F+ E + SL++ +L + + L ++ L L++ KE++ +
Sbjct: 1180 ERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQESEKEKECLQHELQ 1239
Query: 165 ELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHK 224
+ D+ S +L+D S + + +I + +S + + N+N+ LQ S +
Sbjct: 1240 TIRGDLETS--NLQDMQSQEISGLKDCEIDAEEKYISGPHE---LSTSQNDNAHLQCSLQ 1294
Query: 225 QLFQQEAEVWK-GEVSELNKQKITFE--DSKVHAEQVLNDKENHIKTLTGHLPMMKDQAA 281
+ E+ K E+ + K ++ E DS+ + L + ++ D +
Sbjct: 1295 TTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLNEVKILNDDSG 1354
Query: 282 VLEEDTTDD---------DNLELEVNSQWENGANLDDPLKGALKKL-IHAAKLNVSLKSL 331
+L + +D N + V+ + +N + L + K++ +H A+L SL
Sbjct: 1355 LLHGELVEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLSDKEVQMHFAELQEKFLSL 1414
Query: 332 EGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKL-KIM--- 387
+ E + Q ++ EL QT +SL++EN+ + + Q L K M
Sbjct: 1415 QSEHKILHDQHCQMSSKMSEL-------QTYVDSLKAENLVLSTNLRNFQGDLVKEMQLG 1467
Query: 388 -------------------------TEFY-----QEDEMKLYRKL---------TVEENY 408
+ FY Q +M L L +V+E +
Sbjct: 1468 LEEGLVPSLSSSCVPDSSSLSSLGDSSFYRALLEQTGDMSLLSNLEGAVSANQCSVDEVF 1527
Query: 409 RIE-EEEKLSKVE--EKLSRATEQLET----YRKLAKDLEEELERTVHFYQKQVISYEKR 461
+EE L++ E ++ E+LE+ YR+ + LEE++E K++ E+
Sbjct: 1528 CSSLQEENLTRKETPSAPAKGVEELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQ- 1586
Query: 462 GHDNWLAARTAERNLSDLRK----ENAHNKQKLTETELKFE 498
+ + L LRK EN +QKLT L+ E
Sbjct: 1587 ------LLSSERQELDCLRKQYLSENEQWQQKLTSVTLEME 1621
Score = 35.4 bits (80), Expect = 0.20
Identities = 89/445 (20%), Positives = 171/445 (38%), Gaps = 41/445 (9%)
Query: 82 LSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSE 141
L L E + LEK ++++ E + + E E+ + E + L+ ++ N +
Sbjct: 1552 LESLCEVYRQSLEK---LEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQ 1608
Query: 142 LEDEI----LCLEKDLKEEKSKHSQQDELMADISK-SIQSLEDESKSLKSQIAEAKIICK 196
+ ++ L +E L EK K ++Q L ++++ +Q L+ S+SL E I
Sbjct: 1609 WQQKLTSVTLEMESKLAAEK-KQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDAI--- 1664
Query: 197 TFKMSEERRAIAIKDALNENSQLQTSHK------QLFQQEAEVWKGEVSELNKQKITFED 250
K+ +E ++ H + QQ+ + +++E K T E
Sbjct: 1665 ---QGRNESCDISKEHTSETTERTPKHDVHQICDKDAQQDLNLDIEKITETGAVKPTGEC 1721
Query: 251 S-----KVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEE---DTTDDDNLELEVNSQWE 302
S + E DK L A V + + D NL+L V
Sbjct: 1722 SGEQSPDTNYEPPGEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHNLQLRVKETSN 1781
Query: 303 NGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ 362
L ++ +K+ L +K L+ + + +QL + EL + + L+ +
Sbjct: 1782 ENLRLLHVIEDRDRKV---ESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKE 1838
Query: 363 QESLQSENIYFESENQKLQQKLKIMTEFYQEDEM---KLYRKLTVEENYRIEE--EEKLS 417
L + YF ++Q+L Q+++ + EM K R+ + ++ + +E+
Sbjct: 1839 NSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSSREDIGDNVAKVNDSWKERFL 1898
Query: 418 KVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLS 477
VE +LSR + + A LE +LE Q + + EK + E LS
Sbjct: 1899 DVENELSRIRSEKASIEHEALYLEADLE----VVQTEKLCLEKDNENKQKVIVCLEEELS 1954
Query: 478 DLRKENAHNKQKLTETELKFELLEK 502
+ E + +L K L++
Sbjct: 1955 VVTSERNQLRGELDTMSKKTTALDQ 1979
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 78.2 bits (191), Expect = 3e-14
Identities = 104/451 (23%), Positives = 191/451 (42%), Gaps = 51/451 (11%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEI 146
++K + LE +L+QK E + + + K A E + A +L N L++++
Sbjct: 522 DQKIQNLE--ALLQKSKENISLLEKEREDLYAKIQAGEGET--AVLNQLQEKNHTLQEQV 577
Query: 147 LCLEKDLKEEKSKHSQQDELMADISKS----IQSLEDESKSLKSQIAEAKIICKTFKMSE 202
L + LK + H Q E + D + +++ +D SL++ + E K
Sbjct: 578 TQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKV 637
Query: 203 ERRAIAIK---DALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQ--KITFEDSKVHAEQ 257
+ I IK + L +T+ + Q + + + + ++ KIT + +V A+
Sbjct: 638 SQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAK- 696
Query: 258 VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKK 317
L DK+ H L HL K++ LE+ T + LE ++ + + + AL+
Sbjct: 697 -LQDKQEHCSQLESHLKEYKEKYLSLEQKT---EELEGQIKKLEADSLEVKASKEQALQD 752
Query: 318 LIHAAKLNVSL--------KSLEGERNHIIIQLSEVD-KTKEELTEHIKNLQTQQESLQS 368
L +LN L K LE E+ I+ + +D + K E E IK T+QE
Sbjct: 753 LQQQRQLNTDLELRATELSKQLEMEKE--IVSSTRLDLQKKSEALESIKQKLTKQE---E 807
Query: 369 ENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEE-----KLSKVEEKL 423
E + + + L Q+ KI Q +E+ + TV E +++ E+ +LS V++KL
Sbjct: 808 EKQILKQDFETLSQETKI-----QHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKL 862
Query: 424 SRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKE- 482
S+ ++ L K+ + E E+ + ++ EK + + N +KE
Sbjct: 863 SKVSDSL-------KNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKEL 915
Query: 483 -NAHNKQKLTETELKFELLEKDPNALDVSNT 512
+ K+K +LK EL + NT
Sbjct: 916 KKSLEKEKEASHQLKLELNSMQEQLIQAQNT 946
Score = 76.6 bits (187), Expect = 8e-14
Identities = 97/457 (21%), Positives = 190/457 (41%), Gaps = 58/457 (12%)
Query: 87 EEKCKLLEKFSLIQKEY---EGYEVESSLEDASFEKAAAE---EARSLEATCEKLNRSNS 140
EE K LEK+ +Q++ +G +SS E S E+ E E +++ + + +
Sbjct: 107 EELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAA 166
Query: 141 ELEDEILCLEKDLKEEKSKHSQQDELMADISKS-------IQSLEDESKS---------L 184
+L EI ++ EE+S ++ + +++ IQ L+ E L
Sbjct: 167 QLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVL 226
Query: 185 KSQIAEAKIICKTFKMSEERRAIAIKDALNE-NSQLQTSHKQLFQQEAEVWKGE------ 237
K ++ + + + + ER + +KD + SQ +S + Q +E+ KG
Sbjct: 227 KKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVY 286
Query: 238 VSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD----NL 293
V EL K K + +N+ +TLT +L + LEE ++ N+
Sbjct: 287 VQELQKLKSS-----------VNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNI 335
Query: 294 ELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELT 353
+ ++ + + L L + L +++V L + +LSEV+ + L
Sbjct: 336 QATLHQKDLDCQQLQSRLSASETSL---HRIHVELSEKGEATQKLKEELSEVETKYQHLK 392
Query: 354 EHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEE 413
K LQ Q+E + + +SE +L KL E +L + + +++E
Sbjct: 393 AEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKE 452
Query: 414 EKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAE 473
++++ ++ KLSR EQL+ + +L+ +L++T +Q+Q + R A+
Sbjct: 453 QQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQ----QALQQSTTAKLREAQ 508
Query: 474 RNLSDLRKENAHNKQKLTETEL-------KFELLEKD 503
+L + ++ QK+ E LLEK+
Sbjct: 509 NDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKE 545
Score = 69.7 bits (169), Expect = 1e-11
Identities = 99/427 (23%), Positives = 192/427 (44%), Gaps = 48/427 (11%)
Query: 94 EKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDL 153
EK+ ++++ E E + +A + A + ++L+ ++ + N++LE L K L
Sbjct: 716 EKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQ-DLQQQRQLNTDLELRATELSKQL 774
Query: 154 KEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDAL 213
+ EK S D+ K ++LE + L Q E +I+ + F+ + I ++ L
Sbjct: 775 EMEKEIVSST---RLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEE-L 830
Query: 214 NENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHL 273
N Q + Q + E E E+S + + DS +++ +KEN
Sbjct: 831 NNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEF-EKENQ-------- 881
Query: 274 PMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAA-KLNVSLKSLE 332
K +AA+L+ + T + L+ ++ Q EN LK +L+K A+ +L + L S++
Sbjct: 882 ---KGKAAILDLEKTCKE-LKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQ 937
Query: 333 GERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQ 392
+ L + +K +++L +I L+ E + + + LQ +LKI
Sbjct: 938 EQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQI-------EALQGELKIAVLQKT 990
Query: 393 EDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDL---EEEL----- 444
E E KL ++LT E+EK+S ++ ++ ET+++L D E EL
Sbjct: 991 ELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQ---ETFKQLQSDFYGRESELLATRQ 1047
Query: 445 -----ERTVHFYQKQVISYEKR-GHDNWL--AARTAERNLSDLRKENAHNKQKLTETELK 496
E + Q+ +IS + G+ N L +TA+ + L +++A +Q+L E
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAK---ATLEQDSAKKEQQLQERCKA 1104
Query: 497 FELLEKD 503
+ ++K+
Sbjct: 1105 LQDIQKE 1111
Score = 66.6 bits (161), Expect = 8e-11
Identities = 96/485 (19%), Positives = 204/485 (42%), Gaps = 82/485 (16%)
Query: 70 LYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLE 129
+YV QKL ++++ L ++ L E +L++KE + ++E + S K ++++
Sbjct: 285 VYVQELQKLKSSVNELTQKNQTLTE--NLLKKEQDYTKLEEKHNEESVSK------KNIQ 336
Query: 130 ATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIA 189
AT + + +L+ + E L + S++ E + + + +E + + LK++
Sbjct: 337 ATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAE-- 394
Query: 190 EAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKG-----EVSELNKQ 244
FK +++R + L S++ H +L + E ++ + E +L+ +
Sbjct: 395 --------FKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSE 446
Query: 245 KITFEDSKV--------HAEQVLNDKENHIKTLTGHLPMMK----DQAAVLEEDTTDDDN 292
K+ ++ +V E+ L +K + L L K +Q A+ + T
Sbjct: 447 KLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLRE 506
Query: 293 LELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGE-----------RNHIIIQ 341
+ ++ + D ++ L+ L+ +K N+SL E E ++ Q
Sbjct: 507 AQNDLEQVLRQIGDKDQKIQN-LEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQ 565
Query: 342 LSEVDKTKEE----LTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMK 397
L E + T +E LTE +KN Q++ EN++ + + QK + Q+ +
Sbjct: 566 LQEKNHTLQEQVTQLTEKLKN-QSESHKQAQENLHDQVQEQKAHLRAA------QDRVLS 618
Query: 398 LYRKLTVEENYRIEEEEKLSKVEEKLSRATE------------------QLETYRKLAKD 439
L + + E +EK+S+++ ++ TE L+T + +D
Sbjct: 619 LETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQD 678
Query: 440 LEEELER-TVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFE 498
++EL + T Q +K+ H + L E +L + +++ +QK E E + +
Sbjct: 679 KQQELNKITTQLDQVTAKLQDKQEHCSQL-----ESHLKEYKEKYLSLEQKTEELEGQIK 733
Query: 499 LLEKD 503
LE D
Sbjct: 734 KLEAD 738
Score = 66.2 bits (160), Expect = 1e-10
Identities = 79/336 (23%), Positives = 155/336 (46%), Gaps = 36/336 (10%)
Query: 62 SFRSVRSRLYVGREQKLGATLSGL--IEEKCKLLEKFSLIQKEYEGYE----VESSLEDA 115
+F+ ++S Y GRE +L AT L +EEK L ++ + + G + E A
Sbjct: 1027 TFKQLQSDFY-GRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKA 1085
Query: 116 SFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQ 175
+ E+ +A++ + L+ C+ L +++ E EK+L EKSK ++ +E+ K I
Sbjct: 1086 TLEQDSAKKEQQLQERCKALQ----DIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEIT 1141
Query: 176 SLEDESKSLK-------SQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQ 228
L +E KS K + + +AK + K+ + +A ++K A+ + + Q K +
Sbjct: 1142 KLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVK 1201
Query: 229 QEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTT 288
+E E K E E +++K+H+E + +KE G +++A + + T
Sbjct: 1202 KEEEELKKEFIE--------KEAKLHSE--IKEKE------VGMKKHEENEAKLTMQITA 1245
Query: 289 DDDNLELEVNSQWENGANLDDPLKGALKKLI-HAAKLNVSLKSLEGERNHIIIQLSEVDK 347
++NL V +W++ L+ L A L ++++ + ER ++ + + +
Sbjct: 1246 LNENLG-TVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGEG 1304
Query: 348 TKEELTEHIKNLQTQQESLQSENIYFESENQKLQQK 383
E+L + LQ + ++ + ENQ LQ K
Sbjct: 1305 EIEKLQTKVLELQRKLDNTTAAVQELGRENQSLQIK 1340
Score = 62.0 bits (149), Expect = 2e-09
Identities = 85/448 (18%), Positives = 182/448 (40%), Gaps = 46/448 (10%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKL 135
Q+ TL + + + L+ S K+ + + E + +AA + SLE + +L
Sbjct: 567 QEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNEL 626
Query: 136 NRSNSELEDEILCLEKDLK--------EEKSKHSQQDELMADISKSIQSLEDESKSLKSQ 187
N +E ++++ L+ +K E +K +Q+ +L + + +L+D+ + L
Sbjct: 627 NSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKI 686
Query: 188 IAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKIT 247
+ + + +E ++ L E + S +Q+ E +G++ +L +
Sbjct: 687 TTQLDQVTAKLQDKQE-HCSQLESHLKEYKEKYLS----LEQKTEELEGQIKKLEADSLE 741
Query: 248 FEDSKVHA-------EQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
+ SK A Q+ D E L+ L M K+ + D + +
Sbjct: 742 VKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQK 801
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
LK + L K + + L + +L +V KE L + ++
Sbjct: 802 LTKQEEEKQILKQDFETLSQETK--IQHEELNNRIQTTVTELQKVKMEKEALMTELSTVK 859
Query: 361 TQ----QESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKL 416
+ +SL++ FE ENQK + + + + +E L +L V+ ++E+++L
Sbjct: 860 DKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKE----LKHQLQVQMENTLKEQKEL 915
Query: 417 SKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNL 476
K EK A+ QL+ ++ Q+Q+I + N + + N+
Sbjct: 916 KKSLEKEKEASHQLKL--------------ELNSMQEQLIQAQNTLKQNEKEEQQLQGNI 961
Query: 477 SDLRKENAHNKQKL--TETELKFELLEK 502
++L++ + K+++ + ELK +L+K
Sbjct: 962 NELKQSSEQKKKQIEALQGELKIAVLQK 989
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 77.8 bits (190), Expect = 4e-14
Identities = 99/441 (22%), Positives = 190/441 (43%), Gaps = 32/441 (7%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSL-IQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEK 134
+K TL E + K+LE+ + + + S + + K +E + L + ++
Sbjct: 539 EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 135 LNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKII 194
+ S++E E ++K+L+ K K + +EL + LE E++ L+ +I KI
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEEL----ENELHHLEKENELLQKKITNLKIT 654
Query: 195 CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEA-EVWKGEVSELNKQKITFEDSKV 253
C+ + E+ + ++ L + FQ E+ E ++ E N + +S
Sbjct: 655 CEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Query: 254 HAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKG 313
A + + K L +K +L+ + LE+ L L+
Sbjct: 715 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLEN 774
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEV---DKTKEELTEHIKNLQTQQESLQSEN 370
+ KK+ +L L+ LE E + L E+ K E+L + K+L+ + L+ +
Sbjct: 775 SNKKI---QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 371 IYFESENQKLQQKLKIMTEFYQEDEMK----------LYRKLTV--EENYRIEEEEKLSK 418
E EN++L+Q+ +I +E+ +K L +++ + E R++E EK +K
Sbjct: 832 KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Query: 419 VEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSD 478
E + RAT ++T L +DL E +T Q+ EK H+ ER L D
Sbjct: 892 --ELVKRATIDIKTLVTLREDLVSEKLKT----QQMNNDLEKLTHELEKIGLNKERLLHD 945
Query: 479 LRKENAHNKQKLTETELKFEL 499
+++ ++ KL E++L+ L
Sbjct: 946 --EQSTDDRYKLLESKLESTL 964
Score = 77.8 bits (190), Expect = 4e-14
Identities = 110/482 (22%), Positives = 200/482 (41%), Gaps = 68/482 (14%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA----EEARSLE 129
+ ++L + GL E +L + K+ + ++ES L+D E EE +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTLQKNLEELKISS 807
Query: 130 ATCEKLNRSNSELEDEILCLEKDLK--EEKSKHSQQ-----DELMADISKSIQSLEDESK 182
E+L + N LE E LEKD K E+++K +Q D + + + I +LE E+K
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Query: 183 SLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELN 242
+L +I K C K E+ +K A + L T + L +E K + +
Sbjct: 868 TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLV---SEKLKTQQMNND 924
Query: 243 KQKITFEDSKV--------HAEQVLNDKENHIK-----TLTGHLPMMKDQAAV----LEE 285
+K+T E K+ H EQ +D+ ++ TL L + +++ A LEE
Sbjct: 925 LEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEE 984
Query: 286 DTTDDDNLELEVNSQWENGANL------------DDPLKGALKKLIHAAK------LNVS 327
T + L E+ + +N L P+ G K ++ L V
Sbjct: 985 STNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVK 1044
Query: 328 LKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQK---L 384
+ +E ERN+ +Q K+ L +K L+TQ +LQ++ + + + LQ++ L
Sbjct: 1045 DRLIEVERNNATLQAE-----KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTL 1099
Query: 385 KIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEEL 444
+ Q + L + T N + + S +E + ++ E + L L ++
Sbjct: 1100 QTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDH 1159
Query: 445 ERTVHFYQKQVISYE----KRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELL 500
E+ +++Q YE K G ++A +NL ++ +L + + + E L
Sbjct: 1160 EKLELLHERQASEYESLISKHG-----TLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDL 1214
Query: 501 EK 502
EK
Sbjct: 1215 EK 1216
Score = 75.1 bits (183), Expect = 2e-13
Identities = 97/403 (24%), Positives = 180/403 (44%), Gaps = 48/403 (11%)
Query: 124 EARSLEATCEKLNRSNSELE---DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
E +SL T E+L + +E +IL +EK+ + K + + +S+Q+ ++
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 527
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
SK L + A+ + +T + + ER+ IK EN L + L Q+ + V +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQ---IKILEQENEHLNQTVSSLRQRSQISAEARVKD 584
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
+ K+ +S L+ E + + L K++ EE + +LE E
Sbjct: 585 IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE---- 640
Query: 301 WENGANLDDPLKGALKKLIHAAKLNV-SLKSLEGERNHIIIQLSEVDKTKEELTEHIKNL 359
L+K I K+ +++LE E + +L ++ ++ + KNL
Sbjct: 641 -----------NELLQKKITNLKITCEKIEALEQENS----ELERENRKLKKTLDSFKNL 685
Query: 360 QTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKV 419
Q ESL+ EN + EN +L++ + E + MK+ +L +E E+E+L K
Sbjct: 686 TFQLESLEKENSQLDEENLELRRNV----ESLKCASMKM-AQLQLENKELESEKEQLKKG 740
Query: 420 EEKLS---RATEQLE-TYRKLAKDLE-EELERTVHFYQKQVISYEKRGHDNWLAARTAER 474
E L + TE+LE +Y+ L D+E + L++T+ K++ E D + +T ++
Sbjct: 741 LELLKASFKKTERLEVSYQGL--DIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Query: 475 NLSDLR----------KENAHNKQKLTETELKFELLEKDPNAL 507
NL +L+ KEN +Q+ ++ E + LEK+ L
Sbjct: 799 NLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Score = 60.8 bits (146), Expect = 5e-09
Identities = 79/387 (20%), Positives = 169/387 (43%), Gaps = 39/387 (10%)
Query: 134 KLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
K S L E+ + ++ + + ++ E + D + ++ +E E K L+ +
Sbjct: 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS 300
Query: 194 ICKTFKM-SEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSK 252
++ +M +E A+ K + + + S + + E +K V EL + ++K
Sbjct: 301 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK 360
Query: 253 VHAEQVLN------------DKEN-HIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNS 299
E L +KEN +K + M +D E+ ++ N+ LE+
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE-NMTLEMAQ 419
Query: 300 QWENGANLDDPLKGALKKLIHAAKLNVS-LKSLEGERNHIII-QLSEVDKTKEELTEHIK 357
+ +L L L+++ ++L+ + KSL E N + +L +++ + LT+ ++
Sbjct: 420 KQSMDESLH--LGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 477
Query: 358 NLQTQQESLQ---SENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEE 414
L+T +S++ S+ + E ENQ+L +K++I+ +++ L + ++ ++E+
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL-MKEKA 536
Query: 415 KLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAER 474
+L K E L E E K+ + E L +TV +++ + +AE
Sbjct: 537 QLEKTIETL---RENSERQIKILEQENEHLNQTVSSLRQR-------------SQISAEA 580
Query: 475 NLSDLRKENAHNKQKLTETELKFELLE 501
+ D+ KEN + + ET K +E
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIE 607
Score = 56.2 bits (134), Expect = 1e-07
Identities = 95/465 (20%), Positives = 194/465 (41%), Gaps = 69/465 (14%)
Query: 74 REQKLGATLSGLIEEKC----KLLEKFSLIQKEYEGYE--------VESSL----EDASF 117
+E+K+ A L +EE +L ++ ++K YE + V+SS ED +
Sbjct: 971 KEEKIAA-LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKW 1029
Query: 118 EKAAAEEARSLEATCEKL---NRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSI 174
E+ + E R L ++L R+N+ L+ E L+ LK+ +++++ + + +
Sbjct: 1030 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1089
Query: 175 QSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV- 233
SL++++ +L++Q A+ ++ T L + S L+ ++ + ++ ++
Sbjct: 1090 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLK 1149
Query: 234 --WKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD 291
+ + + K ++ E E +++ G L V D D
Sbjct: 1150 SLYDSLIKDHEKLELLHERQASEYESLISKH--------GTLKSAHKNLEVEHRDLEDRY 1201
Query: 292 NLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSL----KSLEGERNHIIIQLSEVDK 347
N L+ Q E+ L+ LK +K++ K + ++ K L GE + + S++ K
Sbjct: 1202 NQLLKQKGQLED---LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK 1258
Query: 348 TKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIM----TEFYQEDEMKLYRKLT 403
E L KNL++ + + E E+E KL+++ + + T+ + E+ K
Sbjct: 1259 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1318
Query: 404 VEENYR----------------IE---EEEKLSKVEEKLSRATEQLETYRKLAKDLEEEL 444
+EE R +E E + L VE++ + ++L R+ + LEE++
Sbjct: 1319 LEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR--QYIDKLNELRRQKEKLEEKI 1376
Query: 445 ERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQK 489
FY R NW+ + R L +K+ +QK
Sbjct: 1377 MDQYKFYDPS----PPRRRGNWITLKM--RKLIKSKKDINRERQK 1415
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 77.8 bits (190), Expect = 4e-14
Identities = 115/477 (24%), Positives = 215/477 (45%), Gaps = 87/477 (18%)
Query: 76 QKLGATLSGLIEEK----CKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT 131
++L + L++EK C++ E +QK + + D + E E
Sbjct: 1357 EELHHNIDDLLQEKKSLECEVEELHRTVQKRQQ----QKDFIDGNVESLMTE------LE 1406
Query: 132 CEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEA 191
EK + + ++ DEI C+EK L + +S+ + D L+A+ + ++++K+ + +A
Sbjct: 1407 IEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA 1466
Query: 192 K-IICKTFKMSEERRAIAIKDALN------ENSQLQTSHKQLFQ---QEAEVWKGEVSEL 241
K + +T +EE A + A+N + LQ K L Q ++ E+ K E++++
Sbjct: 1467 KRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILK-EINKI 1525
Query: 242 -------------NKQKITFEDSKVHAE-QVLNDKENHIKTLTGHLPMMKDQAAVLEEDT 287
K+K+T E K+ + ++ E+H HL ++K+ +L+
Sbjct: 1526 VAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDH------HLQVLKESEVLLQAKR 1579
Query: 288 TDDDNLELEVNSQWENGANLDDPLKGALKKLIH---------AAKLNVSLKSLEGE---- 334
+ + L+ +V SQ + A LD L G K+ +H A L +L+ E E
Sbjct: 1580 AELEKLKSQVTSQQQEMAVLDRQL-GHKKEELHLLQGSMVQAKADLQEALRLGETEVTEK 1638
Query: 335 RNHI---IIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFY 391
NHI L E+ K EL I +TQ ++ E E E + LQ L+ M++
Sbjct: 1639 CNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQE---IEKEEENLQVVLRQMSKHK 1695
Query: 392 QE-----DEMKL----YRKLTVEENYRIEEEEK--LSKVEEKLSRATEQLETYRKLAKDL 440
E D ++L + L ++ + R+ E EK ++ +EEKL +LE +++++
Sbjct: 1696 TELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKL-----ELENLQQISQQQ 1750
Query: 441 EEELERTVHFYQKQVISYEKRGHDNWLA-ARTAERNLSDLRKENAHNKQKLTETELK 496
+ E+E +QKQ++ +KR + A +R + + L KE ++K E K
Sbjct: 1751 KGEIE-----WQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKK 1802
Score = 70.5 bits (171), Expect = 6e-12
Identities = 69/382 (18%), Positives = 171/382 (44%), Gaps = 20/382 (5%)
Query: 86 IEEKCKLLEK-FSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELED 144
++EKC + EK + ++ E S +E ++ EK R L+ ++LNR L +
Sbjct: 1792 LQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELN-VRKLQQELDQLNRDKLSLHN 1850
Query: 145 EILCLEKDLKEEKSKHSQQDELMADI--------------SKSIQSLEDESKSLKSQIAE 190
+I +++ L+E++ + E +A++ +K L E L+ I+E
Sbjct: 1851 DISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISE 1910
Query: 191 AKII---CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKIT 247
C+ + +++++ +++ + EN + +FQ+ + + E S+L K+T
Sbjct: 1911 WANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVT 1970
Query: 248 FEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANL 307
++ + E+ L D+++ + + + +++ L+E+ ++LE ++ +
Sbjct: 1971 LKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSER 2030
Query: 308 DDPLKGALKKLIHAAKLNVSLKS-LEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESL 366
+ L +L+ K S+++ RN + + + +K L E +K ++Q E
Sbjct: 2031 EQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKN 2090
Query: 367 QSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRA 426
E S QK ++++ + E +L ++L + E +++++ ++ R
Sbjct: 2091 LLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQ 2150
Query: 427 TEQLETYRKLAKDLEEELERTV 448
E + R L ++++E+ ++
Sbjct: 2151 MEISDAMRTLKSEVKDEIRTSL 2172
Score = 65.9 bits (159), Expect = 1e-10
Identities = 104/451 (23%), Positives = 194/451 (43%), Gaps = 62/451 (13%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEA--RSLEATCEKLNRSNSEL 142
L ++K KL E+ +QK+ E E ED + E ++ A EKL +
Sbjct: 1536 LSKKKEKLTEELQKLQKDIEMAERN---EDHHLQVLKESEVLLQAKRAELEKLKSQVTSQ 1592
Query: 143 EDEILCLEKDLKEEKSK-HSQQDELM---ADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
+ E+ L++ L +K + H Q ++ AD+ ++++ E E + I E K + +
Sbjct: 1593 QQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEEL 1652
Query: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDS----KVH 254
+ + I + +QL T KQ ++E E + + +++K K ++ ++
Sbjct: 1653 SFQKGELNVQISE---RKTQL-TLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLE 1708
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGA 314
++ K H + ++ + K Q AVLEE LELE N + KG
Sbjct: 1709 NHELQGLKLQHDQRVS---ELEKTQVAVLEE------KLELE------NLQQISQQQKGE 1753
Query: 315 L---KKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHI-----KNLQTQQE-S 365
+ K+L+ K + + E ++ + K KE+L E K QT++ +
Sbjct: 1754 IEWQKQLLERDKREIERMTAESRALQSCVEC--LSKEKEDLQEKCDIWEKKLAQTKRVLA 1811
Query: 366 LQSENIYFESEN-QKLQ---QKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEE 421
EN E N +KL+ +KL+ + D++ L+ ++ + E+ E ++ ++E
Sbjct: 1812 AAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQE 1871
Query: 422 KLSRATEQLETYRKLAKDLEEELERTVHF---------YQKQVISYEKRGHDNWLAARTA 472
+L+ + L LAK ++ L T H QK + + R D T
Sbjct: 1872 ELANVQDHLN----LAK--QDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETK 1925
Query: 473 ERNLSDLRKENAHNKQKLTETELKFELLEKD 503
++ L L+ E NK KL + E+ F+ L+K+
Sbjct: 1926 QQQLQVLQNEIEENKLKLVQQEMMFQRLQKE 1956
Score = 62.0 bits (149), Expect = 2e-09
Identities = 94/473 (19%), Positives = 197/473 (41%), Gaps = 70/473 (14%)
Query: 75 EQKLGATLSGLIEEKCKL---LEKFSLIQKEYEGYEVESSLEDASFEK---AAAEEARSL 128
E+ L L + + K +L L+ L E +G +++ + EK A EE L
Sbjct: 1681 EENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLEL 1740
Query: 129 EATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQI 188
E + + E+E + LE+D +E E M S+++QS + K +
Sbjct: 1741 ENLQQISQQQKGEIEWQKQLLERDKREI--------ERMTAESRALQSCVECLSKEKEDL 1792
Query: 189 AEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITF 248
E I + K+++ +R +A A ENS+++ S+ + + + E+ +LN+ K++
Sbjct: 1793 QEKCDIWEK-KLAQTKRVLA---AAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSL 1848
Query: 249 EDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEED---TTDDDNLELEVN------- 298
+ +Q L +K + +L L ++D + ++D TT ++ L
Sbjct: 1849 HNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDI 1908
Query: 299 SQWENGAN---------------LDDPLKGALKKLIHA---------------AKLNVSL 328
S+W N L + ++ KL+ +KL S
Sbjct: 1909 SEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSK 1968
Query: 329 KSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMT 388
+L+ +++ + +L++ +++ + + + +LQ E + ES + L Q + ++
Sbjct: 1969 VTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLS 2028
Query: 389 EFYQEDEMKLYRKLTVEEN----------YRIEEEEKLSKVEEKLSRATEQLETYR-KLA 437
E Q+ K L +++ R + + K E++++ E L+ R +L
Sbjct: 2029 EREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLE 2088
Query: 438 KDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKL 490
K+L E+ + QK++ + E DN AR + L+ ++ E K+++
Sbjct: 2089 KNLLEQKQEN-SCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQM 2140
Score = 50.1 bits (118), Expect = 8e-06
Identities = 73/337 (21%), Positives = 138/337 (40%), Gaps = 57/337 (16%)
Query: 123 EEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESK 182
+EA LE EK + + + EI L+ + SK + + A S Q L+ +K
Sbjct: 510 QEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNK 569
Query: 183 S---LKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVS 239
L+S++ E I+ + K +EE IKD + ++ Q + + +++ E G +S
Sbjct: 570 QYQQLESRLDE--ILSRIAKETEE-----IKDLEEQLTEGQIAANEALKKDLE---GVIS 619
Query: 240 ELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNS 299
L + T + A+ + +TL L ++ + LE D +N+ E+
Sbjct: 620 GLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKEL-- 677
Query: 300 QWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQL--------SEVDKTKEE 351
A L+ L+ ++N SL+ +G+ + +L +E ++ KEE
Sbjct: 678 -----AELESALQ-------EQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEE 725
Query: 352 LTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIE 411
L + + Q +Q +LQ+E E E Q L+ L + + E
Sbjct: 726 LEKVTRLTQLEQSALQAE---LEKERQALKNALG-------------------KAQFSEE 763
Query: 412 EEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTV 448
+E++ S++ KL + ++ KD + L V
Sbjct: 764 KEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVV 800
Score = 48.9 bits (115), Expect = 2e-05
Identities = 92/426 (21%), Positives = 180/426 (42%), Gaps = 66/426 (15%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGYEVESS------LEDASFEKAAAEEAR---SLEATCEKL 135
L +EK LL++ + +++E + E+ + E A E A E+ SL+ T L
Sbjct: 642 LRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDL 701
Query: 136 NRSNSELEDEILCLEKD---LKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAK 192
+ +ELE + + + LKEE K ++ +L ++ LE E ++LK+ + +A+
Sbjct: 702 SAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQA--ELEKERQALKNALGKAQ 759
Query: 193 IICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKG---------EVSELNK 243
+ + + E A +K ++N+ L+ K V G V EL +
Sbjct: 760 FSEEKEQENSELHA-KLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRR 818
Query: 244 Q-KITFEDSKVHAE-----QVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELE- 296
+ K+ + +H+ + L D + + +D+A V E ++ L+ E
Sbjct: 819 KLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEK 878
Query: 297 -VNSQWENGANLDDPLKGALK--KLIHAAK----------LNVSLKSLEGERNHIIIQLS 343
Q E + L+ + K H A+ L +LKS+E + +QL
Sbjct: 879 LATGQEEFRQACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQ 938
Query: 344 EVDKTKEELTEHIKNLQTQ---QESLQSENIY-FESENQKLQQ------KLKIMTEFYQE 393
E D+ KE + ++ L+ + +++ E ++ + E +KL++ KL +
Sbjct: 939 EADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAK 998
Query: 394 DEMK----LYRKLTVEENYRIEEEEKLSK----VEEKLSRATEQLETYRKLAKDLEE--- 442
D++K K+ E ++E E+ S+ L+RA ++E + L + E
Sbjct: 999 DQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFR 1058
Query: 443 -ELERT 447
E+E+T
Sbjct: 1059 LEMEKT 1064
Score = 45.8 bits (107), Expect = 2e-04
Identities = 91/416 (21%), Positives = 170/416 (40%), Gaps = 79/416 (18%)
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEE 203
+E+ LE+DL+++ + + + I++ + +KSLK + K C+ K
Sbjct: 270 EEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLN 329
Query: 204 RRAIAIKDALNENSQLQTSHKQLFQQEA-----------EVWKGEVSELNKQ-------- 244
+ +K E ++ +L Q+ A + E +E++K
Sbjct: 330 TKNELLKQKTIELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKAPDESPYIG 389
Query: 245 KITFEDSKVHAEQVLNDK---------------ENHIKTLTGHLPM--------MKDQAA 281
K ++ + E + D N L GH P+ K AA
Sbjct: 390 KSRYKRNMFATESYIIDSAQAVQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAA 449
Query: 282 V--LEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGE----- 334
L E + + E ++ E L++ ++ LKK+ A K ++ K L G
Sbjct: 450 QTRLSELHDEIEKAEQQILRATEEFKQLEEAIQ--LKKISEAGK-DLLYKQLSGRLQLVN 506
Query: 335 --RNHIIIQLSEVDKTKEELT---EHIKNLQTQQESLQS---ENIYFESENQKLQQKLKI 386
R + +++K K+E+ + IK+LQ +SL S ++ + +++ +Q+L I
Sbjct: 507 KLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDI 566
Query: 387 MTEFYQEDEMKLYRKLTVEENYRI-EEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELE 445
M + YQ+ E +L L+ RI +E E++ +EE+L+ Q+ L KD LE
Sbjct: 567 MNKQYQQLESRLDEILS-----RIAKETEEIKDLEEQLTEG--QIAANEALKKD----LE 615
Query: 446 RTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLE 501
+ Q+ + + + + A A+ LR E Q+LTE E + + LE
Sbjct: 616 GVISGLQEYLGTIKGQ-------ATQAQNECRKLRDEKETLLQRLTEVEQERDQLE 664
Score = 40.8 bits (94), Expect = 0.005
Identities = 75/355 (21%), Positives = 144/355 (40%), Gaps = 71/355 (20%)
Query: 142 LEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMS 201
LE+E+ LE ++ KSK ++ + A +S + +E+ ++ + E K + ++
Sbjct: 1321 LENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSL--ECEVE 1378
Query: 202 EERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLND 261
E R + Q QQ+ + G V L ++ E S H E ++++
Sbjct: 1379 ELHRTV-----------------QKRQQQKDFIDGNVESL-MTELEIEKSLKHHEDIVDE 1420
Query: 262 KENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHA 321
E KTL +++ +L E E E++ E N + A + L+
Sbjct: 1421 IECIEKTLLKRRSELREADRLLAE-------AESELSCTKEKTKNAVEKFTDAKRSLLQT 1473
Query: 322 AKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQ 381
+ LE + L + D + +++LQ + L+ Q
Sbjct: 1474 ES---DAEELERRAQETAVNLVKAD-------QQLRSLQADAKDLE-------------Q 1510
Query: 382 QKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLE 441
K+K QE+ +K K+ ++ + + LSK +EKL TE+L+ KL KD+E
Sbjct: 1511 HKIK------QEEILKEINKIVAAKD---SDFQCLSKKKEKL---TEELQ---KLQKDIE 1555
Query: 442 EELERTVHFYQ----KQVISYEKRGHDNWLAAR--TAERNLSDLRKENAHNKQKL 490
H Q +V+ KR L ++ + ++ ++ L ++ H K++L
Sbjct: 1556 MAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEEL 1610
Score = 38.5 bits (88), Expect = 0.024
Identities = 77/411 (18%), Positives = 164/411 (39%), Gaps = 60/411 (14%)
Query: 102 EYEGYEVE-SSLEDASFE-KAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSK 159
E+ E E S LED K+ E R + A+ + + EL I L L+E+KS
Sbjct: 1317 EHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDL---LQEKKSL 1373
Query: 160 HSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSE---ERRAIAIKDALNEN 216
+ +EL + K Q + +++S + E +I K+ K E + K L
Sbjct: 1374 ECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIE-KSLKHHEDIVDEIECIEKTLLKRR 1432
Query: 217 SQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMM 276
S+L+ + + L + E+E+ T E +K E+ + K + ++T
Sbjct: 1433 SELREADRLLAEAESEL-----------SCTKEKTKNAVEKFTDAKRSLLQT-------- 1473
Query: 277 KDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERN 336
+D + LE N D L+ + + + + E N
Sbjct: 1474 ----------ESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEIN 1523
Query: 337 HIIIQLSE----VDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQ 392
I+ + K KE+LTE ++ LQ E + E + ++ ++ +++ + +
Sbjct: 1524 KIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERN----EDHHLQVLKESEVLLQAKR 1579
Query: 393 EDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQ 452
+ KL ++T ++++++ ++ +L E+L + + +L+ + +
Sbjct: 1580 AELEKLKSQVT-------SQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGE 1632
Query: 453 KQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKD 503
+V EK H R + L +L + +++E + + L++++
Sbjct: 1633 TEVT--EKCNH-----IREVKSLLEELSFQKGELNVQISERKTQLTLIKQE 1676
Score = 36.6 bits (83), Expect = 0.091
Identities = 38/183 (20%), Positives = 77/183 (42%), Gaps = 10/183 (5%)
Query: 328 LKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIM 387
LKS + E + + +K EEL +I +L +++SL+ E QK QQ+
Sbjct: 1335 LKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQ---- 1390
Query: 388 TEFYQEDEMKLYRKLTVEENYRIEEE--EKLSKVEEKLSRATEQLETYRKLAKDLEEELE 445
+F + L +L +E++ + E+ +++ +E+ L + +L +L + E EL
Sbjct: 1391 KDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELS 1450
Query: 446 RTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPN 505
T + V + D + E + +L + L + + + L+ D
Sbjct: 1451 CTKEKTKNAVEKFT----DAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAK 1506
Query: 506 ALD 508
L+
Sbjct: 1507 DLE 1509
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 77.4 bits (189), Expect = 5e-14
Identities = 104/458 (22%), Positives = 192/458 (41%), Gaps = 54/458 (11%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE 133
R ++ G S IE K +F ++++ E ++ A+ K A+ L +
Sbjct: 1150 RLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKHADSVAELGEQID 1209
Query: 134 KLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
L R +LE K+ E K + M +SKS +LE ++L+ Q++EA+
Sbjct: 1210 NLQRVKQKLE-------KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEAR- 1261
Query: 194 ICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKV 253
K E +R+++ + + S+LQT +L +Q E + VS+L++ K F
Sbjct: 1262 ----GKNEEIQRSLS--ELTTQKSRLQTEAGELSRQLEEK-ESIVSQLSRSKQAFTQQTE 1314
Query: 254 HAEQVLNDKENHIKTLTGH-LPMMKDQAAVLEEDTTDDDNLELEVN----------SQWE 302
++ L ++EN K H L + +L E ++ + E+ +QW
Sbjct: 1315 ELKRQL-EEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR 1373
Query: 303 NGANLD-----DPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIK 357
D + L+ A KKL A +L S + +E + + + ++KTK+ L ++
Sbjct: 1374 TKYETDAIQRTEELEEAKKKL--AQRLQDSEEQVEA----VNAKCASLEKTKQRLQGEVE 1427
Query: 358 NLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLS 417
+L E S + + + + L +E + +L L + E L
Sbjct: 1428 DLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTE----LF 1483
Query: 418 KVEEKLSRATEQLETYRKLAKDLEEELE----------RTVHFYQKQVISYEKRGHDNWL 467
K++ A +QLET ++ K+LE+E+ +T+H +K E D L
Sbjct: 1484 KLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQL 1543
Query: 468 AARTAERNLSDLRKENAHNKQKLTE--TELKFELLEKD 503
A AE L + + +LT+ +E+ ++ EKD
Sbjct: 1544 ALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKD 1581
Score = 65.1 bits (157), Expect = 2e-10
Identities = 95/473 (20%), Positives = 192/473 (40%), Gaps = 46/473 (9%)
Query: 63 FRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA 122
F ++ L +K AT+ ++ L K +KE E V E +
Sbjct: 834 FFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQ 893
Query: 123 EEARSL---EATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED 179
E+ +L E C++L ++ +LE +I KE + ++E+ A+++ + LED
Sbjct: 894 AESENLLDAEERCDQLIKAKFQLEAKI-------KEVTERAEDEEEINAELTAKKRKLED 946
Query: 180 ESKSLKSQIAEAKIIC------------KTFKMSEERRAI--AIKDALNENSQLQTSHKQ 225
E LK I + ++ K ++EE + I E LQ +H+Q
Sbjct: 947 ECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ 1006
Query: 226 LFQQEAEVWKGEVSELNKQKITFE------DSKVHAEQVLN-DKENHIKTLTGHLPMMKD 278
+ + + +V+ LNK K E +S + E+ L D E + + L G L + ++
Sbjct: 1007 AL-DDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQE 1065
Query: 279 QAAVLEEDTTD-DDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNH 337
LE D D+ L+ + + + ++D L+ +L ++ LE E
Sbjct: 1066 SILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE--- 1122
Query: 338 IIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESE---NQKLQQKLKIMTEFYQED 394
I + + KT+++ +++ + L+ E L+ ++ N+K + + + +E
Sbjct: 1123 IEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEA 1182
Query: 395 EMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQ 454
++ + + +L + + L R ++LE + K ++L ++ K
Sbjct: 1183 TLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKS 1242
Query: 455 VISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNAL 507
+ EK RT E LS+ R +N ++ L+E + L+ + L
Sbjct: 1243 KANLEK-------ICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGEL 1288
Score = 58.9 bits (141), Expect = 2e-08
Identities = 83/408 (20%), Positives = 168/408 (41%), Gaps = 40/408 (9%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQK--EYEGYEVESSLEDASFEKAAAEEARSLEATC 132
EQ++ A L+ I E K + + +K E E +++ +LE+A EEA+ L
Sbjct: 1507 EQEI-ADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAE-AALEHEEAKILRIQL 1564
Query: 133 E------KLNRSNSELEDEILCLEKD-----------LKEEKSKHSQQDELMADISKSIQ 175
E +++R +E ++EI L+++ L E ++ L + +
Sbjct: 1565 ELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLN 1624
Query: 176 SLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWK 235
+E + Q AE ++ + + + + DAL L+ + ++ A + +
Sbjct: 1625 EIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLK-EQLAIVERRANLLQ 1683
Query: 236 GEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGH------------LPMMKDQAAVL 283
EV EL E ++ AEQ L D ++ L +M+ Q+ V
Sbjct: 1684 AEVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEV- 1742
Query: 284 EEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLS 343
E+ + D N E + + A + + LK H ++ +L+ + H + +
Sbjct: 1743 EDASRDARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAE 1802
Query: 344 EV-----DKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKL 398
++ K ++L I+ L+ + E Q +N +K ++++K +T +ED +
Sbjct: 1803 QLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNV 1862
Query: 399 YRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELER 446
R + + +++ + + EE +A L +RK +LEE ER
Sbjct: 1863 LRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEER 1910
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 77.0 bits (188), Expect = 6e-14
Identities = 110/483 (22%), Positives = 198/483 (40%), Gaps = 69/483 (14%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA----EEARSLE 129
+ ++L + GL E +L + K+ + ++ES L+D E EE +
Sbjct: 750 KTERLEVSYQGLDIENQRLQKTLENSNKKIQ--QLESELQDLEMENQTLQKNLEELKISS 807
Query: 130 ATCEKLNRSNSELEDEILCLEKDLK--EEKSKHSQQ-----DELMADISKSIQSLEDESK 182
E+L + N LE E LEKD K E+++K +Q D + + + I +LE E+K
Sbjct: 808 KRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENK 867
Query: 183 SLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELN 242
+L +I K C K E+ +K A + L T + L +E K + +
Sbjct: 868 TLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLV---SEKLKTQQMNND 924
Query: 243 KQKITFEDSKV--------HAEQVLNDKENHI------KTLTGHLPMMKDQAAV----LE 284
+K+T E K+ H EQ +D + TL L + +++ A LE
Sbjct: 925 LEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLE 984
Query: 285 EDTTDDDNLELEVNSQWENGANL------------DDPLKGALKKLIHAAK------LNV 326
E T + L E+ + +N L P+ G K ++ L V
Sbjct: 985 ESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKV 1044
Query: 327 SLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQK--- 383
+ +E ERN+ +Q K+ L +K L+TQ +LQ++ + + + LQ++
Sbjct: 1045 KDRLIEVERNNATLQAE-----KQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTT 1099
Query: 384 LKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEE 443
L+ Q + L + T N + + S +E + ++ E + L L ++
Sbjct: 1100 LQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKD 1159
Query: 444 LERTVHFYQKQVISYE----KRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFEL 499
E+ +++Q YE K G ++A +NL ++ +L + + + E
Sbjct: 1160 HEKLELLHERQASEYESLISKHG-----TLKSAHKNLEVEHRDLEDRYNQLLKQKGQLED 1214
Query: 500 LEK 502
LEK
Sbjct: 1215 LEK 1217
Score = 76.3 bits (186), Expect = 1e-13
Identities = 99/441 (22%), Positives = 188/441 (42%), Gaps = 31/441 (7%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSL-IQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEK 134
+K TL E + K+LE+ + + + S + + K +E + L + ++
Sbjct: 539 EKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKE 598
Query: 135 LNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKII 194
+ S++E E ++K+L+ K K + +EL + LE E++ L+ +I KI
Sbjct: 599 TSSKLSKIEFEKRQIKKELEHYKEKGERAEEL----ENELHHLEKENELLQKKITNLKIT 654
Query: 195 CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEA-EVWKGEVSELNKQKITFEDSKV 253
C+ + E+ + ++ L + FQ E+ E ++ E N + +S
Sbjct: 655 CEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLK 714
Query: 254 HAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKG 313
A + + K L +K +L+ + LE+ L L+
Sbjct: 715 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLEN 774
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEV---DKTKEELTEHIKNLQTQQESLQSEN 370
+ KK+ +L L+ LE E + L E+ K E+L + K+L+ + L+ +
Sbjct: 775 SNKKI---QQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK 831
Query: 371 IYFESENQKLQQKLKIMTEFYQEDEMK----------LYRKLTV--EENYRIEEEEKLSK 418
E EN++L+Q+ +I +E+ +K L +++ + E R++E EK +K
Sbjct: 832 KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENK 891
Query: 419 VEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSD 478
E + RAT ++T L +DL E +T Q+ EK H+ ER L D
Sbjct: 892 --ELVKRATIDIKTLVTLREDLVSEKLKT----QQMNNDLEKLTHELEKIGLNKERLLHD 945
Query: 479 LRKENAHNKQKLTETELKFEL 499
+ ++ KL E++L+ L
Sbjct: 946 -EQSTDDSRYKLLESKLESTL 965
Score = 75.1 bits (183), Expect = 2e-13
Identities = 97/403 (24%), Positives = 180/403 (44%), Gaps = 48/403 (11%)
Query: 124 EARSLEATCEKLNRSNSELE---DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
E +SL T E+L + +E +IL +EK+ + K + + +S+Q+ ++
Sbjct: 468 ENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNL 527
Query: 181 SKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSE 240
SK L + A+ + +T + + ER+ IK EN L + L Q+ + V +
Sbjct: 528 SKDLMKEKAQLEKTIETLRENSERQ---IKILEQENEHLNQTVSSLRQRSQISAEARVKD 584
Query: 241 LNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
+ K+ +S L+ E + + L K++ EE + +LE E
Sbjct: 585 IEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE---- 640
Query: 301 WENGANLDDPLKGALKKLIHAAKLNV-SLKSLEGERNHIIIQLSEVDKTKEELTEHIKNL 359
L+K I K+ +++LE E + +L ++ ++ + KNL
Sbjct: 641 -----------NELLQKKITNLKITCEKIEALEQENS----ELERENRKLKKTLDSFKNL 685
Query: 360 QTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKV 419
Q ESL+ EN + EN +L++ + E + MK+ +L +E E+E+L K
Sbjct: 686 TFQLESLEKENSQLDEENLELRRNV----ESLKCASMKM-AQLQLENKELESEKEQLKKG 740
Query: 420 EEKLS---RATEQLE-TYRKLAKDLE-EELERTVHFYQKQVISYEKRGHDNWLAARTAER 474
E L + TE+LE +Y+ L D+E + L++T+ K++ E D + +T ++
Sbjct: 741 LELLKASFKKTERLEVSYQGL--DIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Query: 475 NLSDLR----------KENAHNKQKLTETELKFELLEKDPNAL 507
NL +L+ KEN +Q+ ++ E + LEK+ L
Sbjct: 799 NLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Score = 60.8 bits (146), Expect = 5e-09
Identities = 79/387 (20%), Positives = 169/387 (43%), Gaps = 39/387 (10%)
Query: 134 KLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
K S L E+ + ++ + + ++ E + D + ++ +E E K L+ +
Sbjct: 241 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS 300
Query: 194 ICKTFKM-SEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSK 252
++ +M +E A+ K + + + S + + E +K V EL + ++K
Sbjct: 301 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK 360
Query: 253 VHAEQVLN------------DKEN-HIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNS 299
E L +KEN +K + M +D E+ ++ N+ LE+
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE-NMTLEMAQ 419
Query: 300 QWENGANLDDPLKGALKKLIHAAKLNVS-LKSLEGERNHIII-QLSEVDKTKEELTEHIK 357
+ +L L L+++ ++L+ + KSL E N + +L +++ + LT+ ++
Sbjct: 420 KQSMDESLH--LGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 477
Query: 358 NLQTQQESLQ---SENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEE 414
L+T +S++ S+ + E ENQ+L +K++I+ +++ L + ++ ++E+
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDL-MKEKA 536
Query: 415 KLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAER 474
+L K E L E E K+ + E L +TV +++ + +AE
Sbjct: 537 QLEKTIETL---RENSERQIKILEQENEHLNQTVSSLRQR-------------SQISAEA 580
Query: 475 NLSDLRKENAHNKQKLTETELKFELLE 501
+ D+ KEN + + ET K +E
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIE 607
Score = 57.0 bits (136), Expect = 7e-08
Identities = 105/513 (20%), Positives = 214/513 (41%), Gaps = 74/513 (14%)
Query: 74 REQKLGATLSGLIEEKC----KLLEKFSLIQKEYEGYE--------VESSL----EDASF 117
+E+K+ A L +EE +L ++ ++K YE + V+SS ED +
Sbjct: 972 KEEKIAA-LEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKW 1030
Query: 118 EKAAAEEARSLEATCEKL---NRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSI 174
E+ + E R L ++L R+N+ L+ E L+ LK+ +++++ + + +
Sbjct: 1031 ERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQT 1090
Query: 175 QSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV- 233
SL++++ +L++Q A+ ++ T L + S L+ ++ + ++ ++
Sbjct: 1091 VSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLK 1150
Query: 234 --WKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDD 291
+ + + K ++ E E +++ G L V D D
Sbjct: 1151 SLYDSLIKDHEKLELLHERQASEYESLISKH--------GTLKSAHKNLEVEHRDLEDRY 1202
Query: 292 NLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSL----KSLEGERNHIIIQLSEVDK 347
N L+ Q E+ L+ LK +K++ K + ++ K L GE + + S++ K
Sbjct: 1203 NQLLKQKGQLED---LEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLK 1259
Query: 348 TKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIM----TEFYQEDEMKLYRKLT 403
E L KNL++ + + E E+E KL+++ + + T+ + E+ K
Sbjct: 1260 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1319
Query: 404 VEENYR----------------IE---EEEKLSKVEEKLSRATEQLETYRKLAKDLEEEL 444
+EE R +E E + L VE++ + ++L R+ + LEE++
Sbjct: 1320 LEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQR--QYIDKLNELRRQKEKLEEKI 1377
Query: 445 ERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKE-NAHNKQKLTETELKFELLE-- 501
FY R NW+ + R L +K+ N ++ LT T + + E
Sbjct: 1378 MDQYKFYDPS----PPRRRGNWITLKM--RKLIKSKKDINRERQKSLTLTPTRSDSSEGF 1431
Query: 502 -KDPNALDVSNTAFGREHAPNGPAPLGQRSSET 533
+ P+ +++ G +G LG + S T
Sbjct: 1432 LQLPHQDSQDSSSVGSNSLEDGQT-LGTKKSST 1463
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 76.3 bits (186), Expect = 1e-13
Identities = 97/454 (21%), Positives = 197/454 (43%), Gaps = 51/454 (11%)
Query: 91 KLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRS----------NS 140
K+ E + I++ E E E +L A EK ++ AR LE E+L + N
Sbjct: 1111 KIKELQARIEELEEEIEAEHTLR-AKIEKQRSDLARELEEISERLEEASGATSAQIEMNK 1169
Query: 141 ELEDEILCLEKDLKEEKSKHS--------QQDELMADISKSI-------QSLEDESKSLK 185
+ E E + +DL+E +H +Q + +A++ + I Q LE E LK
Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELK 1229
Query: 186 SQIAEAKIICKTFKMSE---ERRAIAIKDALNE-----NSQLQTSHKQLFQQ-EAEVWKG 236
+I + + S+ ER ++D +E Q Q H Q+ + G
Sbjct: 1230 MEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNG 1289
Query: 237 EVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELE 296
E+S ++K + ++Q L + +K K+ A + + D +L
Sbjct: 1290 ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDL--- 1346
Query: 297 VNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHI 356
+ Q+E + K L++ + A V+ + E + I + E+++ K++L + +
Sbjct: 1347 LREQYEE----EQEAKAELQRALSKANSEVAQWRTKYETD-AIQRTEELEEAKKKLAQRL 1401
Query: 357 KNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKL 416
+ + E+ S+ E Q+LQ +++ + ++ E T+++ R ++ L
Sbjct: 1402 QEAEENTETANSKCASLEKTKQRLQGEVE---DLMRDLERSHTACATLDKKQR-NFDKVL 1457
Query: 417 SKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNL 476
++ ++KL + +LE +K ++ L EL + + Y++ V E +N + + +
Sbjct: 1458 AEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN----KNLQEEI 1513
Query: 477 SDLRKENAHNKQKLTETELKFELLEKDPNALDVS 510
SDL ++ A + L E E +L+E++ + L V+
Sbjct: 1514 SDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVA 1547
Score = 70.9 bits (172), Expect = 4e-12
Identities = 103/483 (21%), Positives = 191/483 (39%), Gaps = 45/483 (9%)
Query: 63 FRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA 122
F ++ L +K AT+ E + L + +KE E V E +
Sbjct: 837 FFKIKPLLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQ 896
Query: 123 EEARSL---EATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED 179
E +L E CE L +S + LE +KE + +++E+ +++ ++LED
Sbjct: 897 SETENLMDAEERCEGLIKSK-------ILLEAKVKELTERLEEEEEMNSELVAKKRNLED 949
Query: 180 ESKSLKSQIAEAKIIC------------KTFKMSEERRAIA--IKDALNENSQLQTSHKQ 225
+ SLK I + ++ K +SEE A+ I E LQ +H+Q
Sbjct: 950 KCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQ 1009
Query: 226 L---FQQEAEVWKGEV---SELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQ 279
Q E + G + ++L +Q E S +++ D E + L G L M ++
Sbjct: 1010 TLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQES 1069
Query: 280 AAVLEEDTTD-DDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGE---- 334
LE D ++ L+ + + A +DD +L+ +L ++ LE E
Sbjct: 1070 IMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAE 1129
Query: 335 ---RNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFY 391
R I Q S++ + EE++E ++ + N E+E QK+++ L+ T +
Sbjct: 1130 HTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQH 1189
Query: 392 QEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLE-TYRKLAKDLE------EEL 444
+ L +K E+ + L +V++KL + +L+ +A ++E +
Sbjct: 1190 EATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNI 1249
Query: 445 ERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDP 504
ERT + Q + + + L+ +N ++ E E L K
Sbjct: 1250 ERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSK 1309
Query: 505 NAL 507
AL
Sbjct: 1310 QAL 1312
Score = 62.0 bits (149), Expect = 2e-09
Identities = 86/396 (21%), Positives = 175/396 (44%), Gaps = 54/396 (13%)
Query: 86 IEEKCKLLEK------FSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSN 139
+E+KC L++ +L + E E + E+ +++ S EE +LE KL +
Sbjct: 947 LEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLS------EEMTALEENISKLTKEK 1000
Query: 140 SELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLE---DESKSLKSQIAEAKIICK 196
L++ DL+ E+ K + ++ A + + LE ++ K L++ + AK +
Sbjct: 1001 KSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLE 1060
Query: 197 -TFKMSEERRAIAIKDALNENSQLQTSHK----QLFQQEAEVWKGEVSELNKQKITFE-- 249
KMS+E +I D N+ Q++ K +L Q +A++ +V L QK E
Sbjct: 1061 GDLKMSQE----SIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQ 1116
Query: 250 ------DSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWE- 302
+ ++ AE L K I+ L ++ + E+ + + ++E+N + E
Sbjct: 1117 ARIEELEEEIEAEHTLRAK---IEKQRSDLARELEEISERLEEASGATSAQIEMNKKREA 1173
Query: 303 ---------NGANLDDPLKGAL---KKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKE 350
A L A K+ A+L + +L+ + + + SE+ +
Sbjct: 1174 EFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEID 1233
Query: 351 ELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTV--EENY 408
++ +I+ L + +++ E + +++ K + T+ + M+ R T E ++
Sbjct: 1234 DMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSH 1293
Query: 409 RIEEEEKL-SKVEEKLSRATEQLETYRKLAKDLEEE 443
R+EE+E L S++ + T+QLE +L + +EEE
Sbjct: 1294 RVEEKESLISQLTKSKQALTQQLE---ELKRQMEEE 1326
Score = 59.3 bits (142), Expect = 1e-08
Identities = 107/525 (20%), Positives = 203/525 (38%), Gaps = 112/525 (21%)
Query: 59 LWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFE 118
L R + RL E+ GAT S IE K +F ++++ E ++ A+
Sbjct: 1143 LARELEEISERL----EEASGAT-SAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLR 1197
Query: 119 KAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLE 178
K A+ L + L R +LE E + +LK E + E + SKS ++E
Sbjct: 1198 KKQADSVAELGEQIDNLQRVKQKLEKE----KSELKMEIDDMASNIEAL---SKSKSNIE 1250
Query: 179 DESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEV 238
++++ Q +E K +E++ I D + ++LQT + +L E + +
Sbjct: 1251 RTCRTVEDQFSE-------IKAKDEQQTQLIHDLNMQKARLQTQNGEL-SHRVEEKESLI 1302
Query: 239 SELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVN 298
S+L K K ++ + ++ + L + +L E ++ + E+
Sbjct: 1303 SQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQ 1362
Query: 299 ----------SQWENGANLD-----DPLKGALKKLIH---------------AAKLNVSL 328
+QW D + L+ A KKL A L +
Sbjct: 1363 RALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTK 1422
Query: 329 KSLEGERNHIIIQLSE--------------VDKTKEELTEHIKNLQTQQESLQSE----- 369
+ L+GE ++ L DK E + + Q + E+ Q E
Sbjct: 1423 QRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLS 1482
Query: 370 -------NIYFE---------SENQKLQQKLKIMTEFYQE-----DEMKLYRKLTVEENY 408
N Y E EN+ LQ+++ +TE E E + +KL +E
Sbjct: 1483 TELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKS 1542
Query: 409 RIE------------EEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQK--- 453
++ EE K+ +V+ +LS+ +L+ RK+ + +EE+E+ Q+
Sbjct: 1543 DLQVALEEVEGSLEHEESKILRVQLELSQVKSELD--RKVI-EKDEEIEQLKRNSQRAAE 1599
Query: 454 ---QVISYEKRGHDNWL-AARTAERNLSDLRKENAHNKQKLTETE 494
V+ E R ++ L + E +L+++ + H+ +++ ET+
Sbjct: 1600 ALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQ 1644
Score = 56.6 bits (135), Expect = 9e-08
Identities = 85/381 (22%), Positives = 162/381 (42%), Gaps = 58/381 (15%)
Query: 107 EVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQ--- 163
EVE SLE EE++ L E L++ SEL+ +++ EKD + E+ K + Q
Sbjct: 1550 EVEGSLEH--------EESKILRVQLE-LSQVKSELDRKVI--EKDEEIEQLKRNSQRAA 1598
Query: 164 DELMADISKSIQSLEDE---SKSLKSQIAEAKIIC--KTFKMSEERRAIAIKDALNENSQ 218
+ L + + I+S D K ++ + E +I +M+E ++ + ++SQ
Sbjct: 1599 EALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQLKDSQ 1658
Query: 219 LQT-----SHKQLFQQEAEVWKGE---VSELNKQKITFEDSKVH---AEQVLNDKENHIK 267
L S++ L +Q A V + + EL + K+ E ++ +EQ L D + ++
Sbjct: 1659 LHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQ 1718
Query: 268 TLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVS 327
L + + LE D + EV + + N ++ K K + AA +
Sbjct: 1719 LLHSQNTSLINTKKKLEADIAQ---CQAEVENSIQESRNAEEKAK---KAITDAAMMAEE 1772
Query: 328 LKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQT------QQESLQSENIYFESENQ--- 378
LK + H+ +++T ++L + + +++ + EN E EN+
Sbjct: 1773 LKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDV 1832
Query: 379 -------------KLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSR 425
K ++K+K MT +ED + R + + + + + + EE +
Sbjct: 1833 EQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKRQAEEAEEQ 1892
Query: 426 ATEQLETYRKLAKDLEEELER 446
A QL R++ +LEE ER
Sbjct: 1893 ANTQLSRCRRVQHELEEAAER 1913
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 74.7 bits (182), Expect = 3e-13
Identities = 105/489 (21%), Positives = 206/489 (42%), Gaps = 61/489 (12%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA---EEARSLEA 130
+ Q+L T L + L ++ + +Q + +++ + ++ + A A EEA
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNM 1101
Query: 131 TCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESK-SLKSQIA 189
+K+ ELE +I L++DL+ E++ ++ ++ D+ + +++L+ E + +L S A
Sbjct: 1102 ALKKIR----ELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAA 1157
Query: 190 EAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFE 249
+ ++ K E+ +K L E ++ +H+ Q+ + V EL +Q +
Sbjct: 1158 QQELRSK-----REQEVNILKKTLEEEAK---THEAQIQEMRQKHSQAVEELAEQLEQTK 1209
Query: 250 DSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWEN-GANLD 308
K + E+ EN L ++ VL + D ++ +V +Q + +
Sbjct: 1210 RVKANLEKAKQTLENERGELA-------NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFN 1262
Query: 309 DPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ----QE 364
+ + + KL V L ++ G LS+ D +LT+ L++Q QE
Sbjct: 1263 EGERVRTELADKVTKLQVELDNVTG-------LLSQSDSKSSKLTKDFSALESQLQDTQE 1315
Query: 365 SLQSENIYFESENQKLQQKLKIMTEFYQ-EDEMKLYRKLTVEENYRIEEEEK-------- 415
LQ EN +QKL + T+ Q EDE +R+ EE EK
Sbjct: 1316 LLQEEN----------RQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQ 1365
Query: 416 LSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERN 475
++ +++K+ + LET ++ + L+++LE ++++V +Y+K ++
Sbjct: 1366 VADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEK----TKTRLQQE 1421
Query: 476 LSDLRKENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRA 535
L DL + H +Q E K +K L T + A R ET+A
Sbjct: 1422 LDDLLVDLDHQRQSACNLEKK---QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKA 1478
Query: 536 FLSPQTLLE 544
+ L E
Sbjct: 1479 LSLARALEE 1487
Score = 63.9 bits (154), Expect = 5e-10
Identities = 98/443 (22%), Positives = 180/443 (40%), Gaps = 50/443 (11%)
Query: 87 EEKCKLLEKFSLIQKEYEGYEVESSLEDASF--EKAAAE-EARSLEATCEKLNRSNSELE 143
+ C L +K QK+++ E A + E+ AE EAR E L R+ E
Sbjct: 1434 QSACNLEKK----QKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 144 DEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI---------- 193
++ LE+ K+ +++ D+ KS+ LE ++L+ Q+ E K
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Query: 194 ICKTFKMSEERRAIAIK-----DALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITF 248
+ K+ E A+K D + Q + KQL +Q E+ + E+ + KQ+
Sbjct: 1550 ATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREM-EAELEDERKQRSMA 1608
Query: 249 EDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLD 308
++ E L D E HI + + Q L+ D LD
Sbjct: 1609 VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR-------------ELD 1655
Query: 309 DPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQS 368
D + L A + LKS+E E + +L+ ++ K + + L + +
Sbjct: 1656 DTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSG 1715
Query: 369 ENIYFESENQKLQQKLKIMTEFYQEDE--MKLYRKLTVEENYRIEEEEKLSKVE----EK 422
+ E ++L+ ++ + E +E++ +L + N +I++ +E +K
Sbjct: 1716 KGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQK 1775
Query: 423 LSRATEQLETYRKLAKDLEEELERTVHF-YQKQVISYEKRGHDNWLAARTAERNLSDLRK 481
A +QLE K K +E+E TV Y+ + + E + A+ E+ ++ ++
Sbjct: 1776 NENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAK------IAQLEEQLDNETKE 1829
Query: 482 ENAHNKQ-KLTETELKFELLEKD 503
A KQ + TE +LK LL+ D
Sbjct: 1830 RQAACKQVRRTEKKLKDVLLQVD 1852
Score = 62.4 bits (150), Expect = 2e-09
Identities = 101/479 (21%), Positives = 200/479 (41%), Gaps = 86/479 (17%)
Query: 60 WRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEK 119
WR F V+ L V R+++ ++ KE E +V EK
Sbjct: 828 WRLFTKVKPLLQVSRQEE-------------------EMMAKEEELVKVR--------EK 860
Query: 120 AAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED 179
A E R E + S+L E L L++ L+ E ++ +EL A ++ Q LE+
Sbjct: 861 QLAAENRLTE-----METLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEE 915
Query: 180 ESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVS 239
L++++ E + C+ + +++ I++ L E + + S +Q Q E + ++
Sbjct: 916 ICHDLEARVEEEEERCQHLQAEKKKMQQNIQE-LEEQLEEEESARQKLQLEKVTTEAKLK 974
Query: 240 ELNKQKITFED--------SKVHAEQV------LNDKENHIKTL----TGHLPMMKDQAA 281
+L +++I ED K+ +++ L ++E K+L H M+ D
Sbjct: 975 KLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE 1034
Query: 282 VLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQ 341
L + LE + +L D + ++ A+L + L E E + +
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQI---AELKMQLAKKEEELQAALAR 1091
Query: 342 LSEVDKTKEELTEHIKNLQTQ----QESLQSENI---YFESENQKLQQKLK-IMTEF--- 390
+ E K + I+ L++Q QE L+SE E + + L ++L+ + TE
Sbjct: 1092 VEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDT 1151
Query: 391 ------------YQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAK 438
+E E+ + +K T+EE + E + + ++ +K S+A E+L + K
Sbjct: 1152 LDSTAAQQELRSKREQEVNILKK-TLEEEAKTHEAQ-IQEMRQKHSQAVEELAEQLEQTK 1209
Query: 439 DLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKF 497
++ LE+ KQ + E+ N + + S+ +++ + +L E ++KF
Sbjct: 1210 RVKANLEKA-----KQTLENERGELANEVKVLLQGKGDSEHKRKKV--EAQLQELQVKF 1261
Score = 58.5 bits (140), Expect = 2e-08
Identities = 97/473 (20%), Positives = 182/473 (38%), Gaps = 62/473 (13%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRS-NSELE 143
L+ E+ + K++ + E E + S +A EEA +A E+LN+ +E+E
Sbjct: 1449 LLAEEKTISAKYAEERDRAEAEAREKETKALSLARAL-EEAMEQKAELERLNKQFRTEME 1507
Query: 144 DEILCLE---KDLKE-EKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFK 199
D + + K + E EKSK + + ++ ++ ++ LEDE ++ + ++ + K
Sbjct: 1508 DLMSSKDDVGKSVHELEKSKRALEQQV-EEMKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Query: 200 MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVL 259
ER D + Q + KQL +Q E+ + E+ + KQ+ ++ E L
Sbjct: 1567 AQFER------DLQGRDEQSEEKKKQLVRQVREM-EAELEDERKQRSMAVAARKKLEMDL 1619
Query: 260 NDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLI 319
D E HI + + Q L+ D LDD + L
Sbjct: 1620 KDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMR-------------ELDDTRASREEILA 1666
Query: 320 HAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQK 379
A + LKS+E E + +L+ ++ K + + L + + + E ++
Sbjct: 1667 QAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRR 1726
Query: 380 LQQKLKIMTEFYQEDE--MKLYRKLTVEENYRIEEEEKLSKVE----EKLSRATEQLETY 433
L+ ++ + E +E++ +L + N +I++ +E +K A +QLE
Sbjct: 1727 LEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQ 1786
Query: 434 RKLAK--------------------------DLEEELERTVHFYQ---KQVISYEKRGHD 464
K K LEE+L+ Q KQV EK+ D
Sbjct: 1787 NKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846
Query: 465 NWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSNTAFGRE 517
L RN + + +L + + + E E++ + S RE
Sbjct: 1847 VLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRE 1899
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 74.7 bits (182), Expect = 3e-13
Identities = 103/477 (21%), Positives = 202/477 (42%), Gaps = 50/477 (10%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDAS-----FEKAAAEEARSLEA 130
Q+L A +S + +L EK S +Q E + V + LE+A F K AA L+
Sbjct: 1262 QELHAKVSEGDRLRVELAEKASKLQNELDN--VSTLLEEAEKKGIKFAKDAASLESQLQD 1319
Query: 131 TCEKLN---RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQ 187
T E L R L I LE++ + + +++E ++ K + +L+ + K +
Sbjct: 1320 TQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKK 1379
Query: 188 IAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVS-ELNKQKI 246
+ + T + EE + +KDA + +L+ K L + E K + EL+ +
Sbjct: 1380 VDDD---LGTIESLEEAKKKLLKDAEALSQRLE--EKALAYDKLEKTKNRLQQELDDLTV 1434
Query: 247 TFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGAN 306
+ H QV ++ E K L K +A E+ D E E + +
Sbjct: 1435 DLD----HQRQVASNLEKKQKKFDQLLAEEKSISARYAEER---DRAEAEAREKETKALS 1487
Query: 307 LDDPLKGALKKLIHAAKLNVSLKS----LEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ 362
L L+ AL+ + N L++ L ++ + + E++K+K L + ++ ++TQ
Sbjct: 1488 LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQ 1547
Query: 363 QESLQSENIYFESENQKLQQKLKIMTEFYQ----------EDEMKLYRKLTVEENYRIEE 412
E L+ E E +L+ ++ M ++ E++ +L K E +E+
Sbjct: 1548 LEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELED 1607
Query: 413 EEK--------LSKVEEKLSRATEQLETYRKLAKDLEEELER---TVHFYQKQVISYEKR 461
E K K+E L Q+E K ++ ++L + + YQ+++
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARAS 1667
Query: 462 GHDNWLAARTAERNLSDLRKENAHNKQKLTETE--LKFELLEKDPNALDVSNTAFGR 516
+ + ++ +E+ L L E +++L +E + E+D A +++N+A G+
Sbjct: 1668 RDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGK 1724
Score = 69.7 bits (169), Expect = 1e-11
Identities = 110/475 (23%), Positives = 214/475 (45%), Gaps = 56/475 (11%)
Query: 107 EVESSLEDASFEKAAAEE------ARSLEATCEKLNRSN--SELEDEILCLEKDLKEEKS 158
E+++ +++ + A EE AR + T K N EL+ +I L++D + EK+
Sbjct: 1073 ELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKA 1132
Query: 159 KHSQQDELMADISKSIQSLEDESK-SLKSQIAEAKIICKTFKMSEERRAIAIKDALNENS 217
++ ++ D+S+ +++L+ E + +L + A+ ++ K + E + ++ N +
Sbjct: 1133 SRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEA 1192
Query: 218 QLQ-------TSHKQLFQQ--EAEVWKGEVSELNKQKITFEDSKVHAE-----QVLNDKE 263
Q+Q T+ ++L +Q +A+ +K + E NKQ + ++ ++ E QV + E
Sbjct: 1193 QIQDMRQRHATALEELSEQLEQAKRFKANL-EKNKQGLETDNKELACEVKVLQQVKAESE 1251
Query: 264 NHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVN---SQWENGA-NLDDPLKGALKKLI 319
+ K L Q L ++ D L +E+ S+ +N N+ L+ A KK I
Sbjct: 1252 HKRKKLDA-------QVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGI 1304
Query: 320 HAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQK 379
AK SL+S + + L E + K L+ I+ L+ ++ SLQ + E +
Sbjct: 1305 KFAKDAASLESQLQDTQEL---LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1361
Query: 380 LQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLS-RATEQLETYRKLAK 438
L++++ + + + K+ L E+ E ++KL K E LS R E+ Y KL K
Sbjct: 1362 LEKQVLALQSQLADTKKKVDDDLGTIESLE-EAKKKLLKDAEALSQRLEEKALAYDKLEK 1420
Query: 439 D---LEEEL-ERTVHF-YQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTET 493
L++EL + TV +Q+QV S ++ + E+++S E +
Sbjct: 1421 TKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEA---- 1476
Query: 494 ELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLG 548
E EK+ AL ++ E A +++ + RA + +D +G
Sbjct: 1477 ----EAREKETKALSLARAL---EEALEAKEEFERQNKQLRADMEDLMSSKDDVG 1524
Score = 65.1 bits (157), Expect = 2e-10
Identities = 99/485 (20%), Positives = 199/485 (41%), Gaps = 68/485 (14%)
Query: 59 LWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVE-SSLEDASF 117
L+ +R+RL ++Q+L L L + E+ ++Q E + + LE+
Sbjct: 902 LFAEAEEMRARL-AAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960
Query: 118 EKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSL 177
E+ A + LE + ++E+EIL LE ++ SK ++ +LM
Sbjct: 961 EEEGARQKLQLEKVTAEAKIK--KMEEEILLLE----DQNSKFIKEKKLM---------- 1004
Query: 178 EDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGE 237
ED SQ+AE + K ++ + I D L E + + +Q ++ GE
Sbjct: 1005 EDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD-LEERLKKEEKTRQELEKAKRKLDGE 1063
Query: 238 VSELNKQKITFEDSKVHAEQVLNDKENHI---------KTL--TGHLPMMKDQAAVLEED 286
++L Q + + L KE + +TL L ++++ A + E
Sbjct: 1064 TTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAEL 1123
Query: 287 TTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEV- 345
D ++ + N + +L + L+ +L + + L +R + +L +
Sbjct: 1124 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1183
Query: 346 -DKTK-----------------EELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIM 387
++TK EEL+E ++ + + +L+ E++N++L ++K++
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVL 1243
Query: 388 TEFYQEDEMK----------LYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYR--- 434
+ E E K L+ K++ + R+E EK SK++ +L + LE
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303
Query: 435 -KLAKD---LEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKL 490
K AKD LE +L+ T Q++ + +K + + E+N ++E +K
Sbjct: 1304 IKFAKDAASLESQLQDTQELLQEE--TRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKN 1361
Query: 491 TETEL 495
E ++
Sbjct: 1362 LEKQV 1366
Score = 64.7 bits (156), Expect = 3e-10
Identities = 108/485 (22%), Positives = 209/485 (43%), Gaps = 68/485 (14%)
Query: 60 WRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESS--LEDASF 117
WR F V+ L V R+++ L EE K+ EK + ++ E E E + LE+ +
Sbjct: 835 WRVFTKVKPLLQVTRQEE---ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNI 891
Query: 118 EKAAAEEARSLEATCE----KLNRSNSELEDEILCLEKDLKEEKSKH----SQQDELMAD 169
+ L A E +L ELE+ + LE ++EE+ ++ +++ ++ A
Sbjct: 892 LAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAH 951
Query: 170 ISKSIQSLEDESKS-----LKSQIAEAKI--ICKTFKMSEERRAIAIKDALNENSQLQTS 222
I + L++E + L+ AEAKI + + + E++ + IK+ ++
Sbjct: 952 IQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAEC 1011
Query: 223 HKQLFQQEAEVWKGEVSELNKQKITFEDSKVH---AEQVLNDKENHIKTLTGHLPMMKDQ 279
QL ++E E K NKQ++ D + E+ + E + L G ++DQ
Sbjct: 1012 SSQLAEEE-EKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQ 1070
Query: 280 AAVLEEDTTDDDNLELEVNSQWENGA---------NLDDPLKGALKKLIHAAKLNVSLKS 330
A L+ D+ L+L + GA + ++ LK + A+L +S
Sbjct: 1071 IAELQAQ-IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFES 1129
Query: 331 LEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEF 390
+ RN + +K K +L+E ++ L+T+ E + + + Q+L+ K
Sbjct: 1130 EKASRN-------KAEKQKRDLSEELEALKTELE----DTLDTTAAQQELRTK------- 1171
Query: 391 YQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHF 450
+E E+ +K EE E ++ + ++ + A E+L + AK + LE+
Sbjct: 1172 -REQEVAELKKALEEETK--NHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEK---- 1224
Query: 451 YQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE--TELKFELLEKDPNALD 508
KQ + + + LA + L ++ E+ H ++KL EL ++ E D ++
Sbjct: 1225 -NKQGLETDNKE----LACEV--KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVE 1277
Query: 509 VSNTA 513
++ A
Sbjct: 1278 LAEKA 1282
Score = 59.3 bits (142), Expect = 1e-08
Identities = 97/485 (20%), Positives = 200/485 (41%), Gaps = 50/485 (10%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQK-----EYEGYEVESSLEDASFEKAAAEEAR-- 126
+ ++L A + L+ K + + ++K E + E+ + LE+ E A E+A+
Sbjct: 1505 QNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLR 1564
Query: 127 ------SLEATCEK-LNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED 179
+++A E+ L + + E++ L K ++E +++ + + A S + +E
Sbjct: 1565 LEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEI 1624
Query: 180 ESKSLKSQIAEA-KIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWK--- 235
+ K L++QI A K + K + +A +KD E + + S ++F Q E K
Sbjct: 1625 DLKDLEAQIEAANKARDEVIKQLRKLQA-QMKDYQRELEEARASRDEIFAQSKESEKKLK 1683
Query: 236 ---GEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDN 292
E+ +L ++ + E ++ HAEQ ++ + I + D+ LE
Sbjct: 1684 SLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQ--- 1740
Query: 293 LELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEEL 352
LE E+ + N L+D + K + LN L + ER+ + D +++L
Sbjct: 1741 LEEELEEEQSNMELLNDRFR---KTTLQVDTLNAELAA---ERS----AAQKSDNARQQL 1790
Query: 353 TEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEE 412
K L+ + + L+ ++ K K + +L +L E R
Sbjct: 1791 ERQNKELKAKLQELEGA----------VKSKFKATISALEAKIGQLEEQLEQEAKERAAA 1840
Query: 413 EEKLSKVEEKLSRATEQLETYRKLAKDLEEELERT---VHFYQKQVISYEKRGHDNWLAA 469
+ + + E+KL Q+E R+ A +E++E+ + ++Q+ E+ +
Sbjct: 1841 NKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASR 1900
Query: 470 RTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQR 529
R +R L D + N +++ + LK L P + S + + H L
Sbjct: 1901 RKLQRELDDATEANEGLSREV--STLKNRLRRGGPISFSSSRSGRRQLHLEGASLELSDD 1958
Query: 530 SSETR 534
+E++
Sbjct: 1959 DTESK 1963
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 74.7 bits (182), Expect = 3e-13
Identities = 100/426 (23%), Positives = 190/426 (44%), Gaps = 70/426 (16%)
Query: 100 QKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSK 159
+ E ++ LE + + A E R L+ ++L + S+ E+++ L L E+++
Sbjct: 1362 EAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAA 1421
Query: 160 HSQ-QDELMA--DISKSIQS-LEDESKSLKSQIAEAKI-IC----KTFKMSEERRA---- 206
++ Q E++ D+ K++ + LE ++K +I + ++ +C K ++ EE RA
Sbjct: 1422 LTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQI 1481
Query: 207 --------IAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQV 258
I+ K+AL EN L Q+E + +G + L K E S+V A+
Sbjct: 1482 QRKLQAALISRKEALKENKSL--------QEELSLARGTIERLTKSLADVE-SQVSAQNK 1532
Query: 259 LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKL 318
D T+ G L +++++ L T+ D LE S + +L L+G +
Sbjct: 1533 EKD------TVLGRLALLQEERDKL---ITEMDRSLLENQSLSSSCESLKLALEGLTEDK 1583
Query: 319 IHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESL--QSENIYFESE 376
K SLKS S++ ++ E +H K LQ + E L EN+ E+E
Sbjct: 1584 EKLVKEIESLKS------------SKIAESTEWQEKH-KELQKEYEILLQSYENVSNEAE 1630
Query: 377 NQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKL 436
+++ + E ++++ +LY KL E + E E++L + E+++ E++ + K
Sbjct: 1631 ------RIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKS 1684
Query: 437 AKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELK 496
+ ELE + +V A TA+ + L NA K++L +++
Sbjct: 1685 KQQKILELEEENDRLRAEVHP----------AGDTAKECMETLLSSNASMKEELERVKME 1734
Query: 497 FELLEK 502
+E L K
Sbjct: 1735 YETLSK 1740
Score = 65.5 bits (158), Expect = 2e-10
Identities = 85/390 (21%), Positives = 164/390 (42%), Gaps = 52/390 (13%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGYEVESSL-----EDASFEKAAAEEARSLEATCEKLNRSN 139
L E+ C +L K L Q E++ ++ + +E A E + + C+ L N
Sbjct: 2228 LKEDNCSVL-KDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGEN 2286
Query: 140 SEL--------------EDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLK 185
EL ++E+ LE +LK K + + D+S S++ +++ +L+
Sbjct: 2287 KELLSQLEETRHLYHSSQNELAKLESELKSLKDQ-------LTDLSNSLEKCKEQKGNLE 2339
Query: 186 SQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQK 245
I + + + K S E+ ++ + S+L H+++ +E ++ +S L+ ++
Sbjct: 2340 GIIRQQEADIQNSKFSYEQLETDLQASRELTSRL---HEEINMKEQKI----ISLLSGKE 2392
Query: 246 ITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDT---TDDDNLELEV----- 297
E +V ++ + IK L L +++ VLEE+ D N +E
Sbjct: 2393 ---EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIK 2449
Query: 298 NSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQ----LSEVDKTKEELT 353
+ A LD +K ++ + LE II++ + E +L
Sbjct: 2450 KENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLK 2509
Query: 354 EHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEE 413
E I+ L++ + L SEN ++E + ++ L + + +L L V+ E E
Sbjct: 2510 EEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQL---LEVQLQQNKELE 2566
Query: 414 EKLSKVEEKLSRATEQLETYRKLAKDLEEE 443
K +K+EEKL + E E R+ L+EE
Sbjct: 2567 NKYAKLEEKLKESEEANEDLRRSFNALQEE 2596
Score = 58.9 bits (141), Expect = 2e-08
Identities = 95/450 (21%), Positives = 179/450 (39%), Gaps = 81/450 (18%)
Query: 83 SGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSEL 142
S I E + EK +QKEYE + S E+ S EA ++ E + + EL
Sbjct: 1595 SSKIAESTEWQEKHKELQKEYE--ILLQSYENVS------NEAERIQHVVEAVRQEKQEL 1646
Query: 143 EDEILCLE-------KDLKEEKSKHSQQDELMADISKSIQS----LEDESKSLKSQIAEA 191
++ E K L+E + + + E M +KS Q LE+E+ L++++ A
Sbjct: 1647 YGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPA 1706
Query: 192 ---------KIICKTFKMSEERRAIAIK-DALNENSQLQTSHKQLFQQEAEVWKGEVSEL 241
++ M EE + ++ + L++ Q S K +E + K ++
Sbjct: 1707 GDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGN 1766
Query: 242 NKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQW 301
++ E ++ H Q N E +++ G +T + D+L +
Sbjct: 1767 VSKQANLEATEKHDNQT-NVTEEGTQSIPG--------------ETEEQDSLSMSTRPTC 1811
Query: 302 ENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQT 361
+ + A N ++ + I L ++D+ KE + + Q
Sbjct: 1812 S-------------ESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQK 1858
Query: 362 QQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEE 421
+E Q+ EN+K +I T+ + E+K+ ++ + N ++ ++E
Sbjct: 1859 NKEFSQT------LENEKNTLLSQISTK---DGELKMLQEEVTKMNLLNQQ------IQE 1903
Query: 422 KLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRK 481
+LSR T+ ET + DLEE L + + +Y + D + E + +L+K
Sbjct: 1904 ELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKK 1963
Query: 482 ---ENAHNKQKL------TETELKFELLEK 502
E KQ+L E+E++ E LEK
Sbjct: 1964 CVSELEEEKQQLVKEKTKVESEIRKEYLEK 1993
Score = 58.9 bits (141), Expect = 2e-08
Identities = 100/479 (20%), Positives = 195/479 (40%), Gaps = 66/479 (13%)
Query: 85 LIEEKCKL--------LEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLN 136
L++EK K+ LEK QKE L++ EK +E + L+ C +
Sbjct: 1975 LVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQ--QEVKQLQKDCIRYQ 2032
Query: 137 RSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLK-----SQIAEA 191
S LE + LE E + E +A + + + E S K +Q A
Sbjct: 2033 EKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAA 2092
Query: 192 KIICKTFKMSEERRA--------IAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNK 243
+++ K+ +E ++ + KD E Q K L +E + + ++ L +
Sbjct: 2093 RVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHL--KEKKNMQEKLDALRR 2150
Query: 244 QKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTT---DDDNLELEVNSQ 300
+K+ E++ + LN K+ ++ L +L Q A + + DD + ++ +
Sbjct: 2151 EKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKK 2210
Query: 301 WE-------------------NGANLDDPLKGALKKLIHAAKLNVSLKSLEGERN----- 336
WE N + L D L+ + IH +L +++ LE ++
Sbjct: 2211 WERKFSDAIQSKEEEIRLKEDNCSVLKDQLR---QMSIHMEELKINISRLEHDKQIWESK 2267
Query: 337 -HIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQ--KLQQKLKIMTEFYQE 393
+QL + K + L K L +Q E ++ ++Y S+N+ KL+ +LK + + Q
Sbjct: 2268 AQTEVQLQQ--KVCDTLQGENKELLSQLE--ETRHLYHSSQNELAKLESELKSLKD--QL 2321
Query: 394 DEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRAT-EQLETYRKLAKDLEEELERTVHFYQ 452
++ + E+ +E + + + + S+ + EQLET + +++L L ++ +
Sbjct: 2322 TDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKE 2381
Query: 453 KQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSN 511
+++IS + A R D + N E E L E++ A+D +N
Sbjct: 2382 QKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEE-NIVLEEENKKAVDKTN 2439
Score = 55.5 bits (132), Expect = 2e-07
Identities = 90/407 (22%), Positives = 175/407 (42%), Gaps = 52/407 (12%)
Query: 82 LSGLIEEKCKLLEKFSLI------QKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKL 135
LS +E+ ++ FS ++++ E+E + ++ +A + + A + L
Sbjct: 2820 LSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQSL 2879
Query: 136 NRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC 195
++ S L+++ L K+LK + ++ Q I++ I L LK+Q+ E +
Sbjct: 2880 KKAMSSLQNDRDRLLKELKNLQQQYLQ-------INQEITELHP----LKAQLQEYQDKT 2928
Query: 196 KTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHA 255
K F++ +E + EN Q QL + E W+ + +Q + K
Sbjct: 2929 KAFQIMQE-------ELRQENLSWQHELHQL-RMEKSSWEIHERRMKEQYLMAISDK--- 2977
Query: 256 EQVLNDKENHIKTL------TGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDD 309
+Q L+ +N I+ L T L + + A E + D + L ++ L+D
Sbjct: 2978 DQQLSHLQNLIRELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLR-TQLND 3036
Query: 310 PLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSE 369
LK +K + +LN + L E+N + IQL + ++ E +H +L L
Sbjct: 3037 SLKEIHQKELRIQQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVL--- 3093
Query: 370 NIYFESENQKLQQ-KLKI-MTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRAT 427
E + Q+LQ L I + +++ ++RK EE E ++ S+ +++L
Sbjct: 3094 ----EKQVQELQAGPLNIDVAPGAPQEKNGVHRKSDPEE--LREPQQSFSEAQQQLCNTR 3147
Query: 428 EQLETYRKLAKDLEEELERTVHFYQKQVISYE---KRGHDNWLAART 471
+++ RKL LEEE ++ V ++ E + H W ++RT
Sbjct: 3148 QEVNELRKL---LEEERDQRVAAENALSVAEEQIRRLEHSEWDSSRT 3191
Score = 53.9 bits (128), Expect = 6e-07
Identities = 83/397 (20%), Positives = 170/397 (42%), Gaps = 45/397 (11%)
Query: 108 VESSLEDASFEKA-AAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEK--------- 157
++S L++ E AE R + + E+L+++ S+ E EI +++ L E+K
Sbjct: 836 LQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQT 895
Query: 158 --SKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNE 215
K Q E+ +++ + L +E SL +I K +EE + K+ + E
Sbjct: 896 IEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAK----KEQVEE 951
Query: 216 NSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPM 275
++++ + KQ + + + + EL + + ++ L + K L +
Sbjct: 952 DNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSR 1011
Query: 276 MKDQAAVLEEDTTDDDNLEL----EVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSL 331
++++ A L++++ + L EV EN + + +++ K +S K
Sbjct: 1012 LEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEK-- 1069
Query: 332 EGERNHIIIQLSEVDKTKEELTEHIK--NLQTQQESLQSENIYFE-SENQKLQQKLKIM- 387
E E HI L E +E+ +K N Q ++ Q + + E SENQ + QKL
Sbjct: 1070 EVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSN 1129
Query: 388 TEFYQEDEMKLYRKLTV--------EENYRIEEEEKL-----------SKVEEKLSRATE 428
T+ D + L ++ V E+++ E EEK+ K++E L+
Sbjct: 1130 TDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKA 1189
Query: 429 QLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDN 465
L+ ++ + L EEL++ Y + ++++ +N
Sbjct: 1190 ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKEN 1226
Score = 53.1 bits (126), Expect = 9e-07
Identities = 123/604 (20%), Positives = 246/604 (40%), Gaps = 82/604 (13%)
Query: 107 EVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLK----EEKSKHSQ 162
E +S + + +K++ EE E EK+ E E+ I L+ L E+ ++ S
Sbjct: 125 EPQSEEQLSKHDKSSTEE----EMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSST 180
Query: 163 QDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRA-IAIKDALNENSQLQ- 220
+ E + + +Q E+ +L++Q+++ + ++ E+ A + L+E+ LQ
Sbjct: 181 EMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQL 240
Query: 221 -------TSHKQLFQ---------QEAEVWKGEVSELNKQKITFEDSKVHA-EQVLNDKE 263
T +Q + +E+ V + +V +L +Q++T + + Q L E
Sbjct: 241 VTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQME 300
Query: 264 NHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAK 323
TL + ++++ +L E +ELEV + + NL + + L++ A +
Sbjct: 301 AEHNTLRNTVETEREESKILLE------KMELEVAERKLSFHNLQEEMHHLLEQFEQAGQ 354
Query: 324 LNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQK 383
L+S R + Q + + EE T HI +LQ + LQS + +N KL Q
Sbjct: 355 AQAELES----RYSALEQKHKAEM--EEKTSHILSLQKTGQELQSACDALKDQNSKLLQ- 407
Query: 384 LKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSR-ATEQLETYRKLA----- 437
++E + T+++ + ++K ++ + L+R +Q ET + +
Sbjct: 408 --------DKNEQAVQSAQTIQQ-LEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVY 458
Query: 438 -KDLEEELERTVHFYQKQVISYE-KRGHDNWLAARTAERNLSDLRKENAHNKQKLTETEL 495
+ + E + QK+V+ E ++G A + L +L+ EN ++T E
Sbjct: 459 NEGTQAVTEENIASLQKRVVELENEKG-----ALLLSSIELEELKAENEKLSSQITLLEA 513
Query: 496 KFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPE 555
+ E D ++S + + + + E+ + T + LS +L E
Sbjct: 514 QNRTGEADREVSEISIVDIANKRSSS--------AEESGQDVLENTFSQKHKELSVLLLE 565
Query: 556 GGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKMMFPPPGQS 615
+ + L Q+ +R E + + D G +P++ K+ GQ
Sbjct: 566 --MKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKM--KVFLEDTGQD 621
Query: 616 YPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNL 675
+P L P E + E+ S E +S + D + E++S++ D L
Sbjct: 622 FP---LMPNEESSLPA-VEKEQASTEHQSRTSEEISLNDAGV--ELKSTKQDGDKSLS-- 673
Query: 676 NVPD 679
VPD
Sbjct: 674 AVPD 677
Score = 51.6 bits (122), Expect = 3e-06
Identities = 112/504 (22%), Positives = 202/504 (40%), Gaps = 108/504 (21%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLED--ASFEKAAAEEARSLEATC 132
EQ+ + LI K +LL++ S +++E + ES E + E+ EE + +
Sbjct: 989 EQRKRKLQAALINRK-ELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYS 1047
Query: 133 EK------------LNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDE 180
EK L ++ SE E E+ + KDL+E+ + Q L+ +++++Q ++
Sbjct: 1048 EKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQ 1107
Query: 181 SKSLKSQIAE-----AKIICKTFKMSEERRAIAIKDAL---------------------- 213
L+++I+E K+I S+ +K+ +
Sbjct: 1108 IDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKIL 1167
Query: 214 ---NENSQLQ-------TSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKE 263
E QLQ TS K + ++ E + EL +QK + + ++ + E
Sbjct: 1168 ALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENE 1227
Query: 264 NH-----------IKTLTGHLPMMKDQAAV-----LEED---TTDDDN----LELEVNSQ 300
N +++ G LP Q + LEE T+ + LE +
Sbjct: 1228 NIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPD 1287
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLS----EVDKTKEE---LT 353
W + + L+G A++ LK +E E+ + +++S E+ K EE L
Sbjct: 1288 WPSHSEDASALQGGTS----VAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVFQLQ 1343
Query: 354 EHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEE 413
E I + ESL++ + E + LQQKL+ + Q ++ R+L +++E
Sbjct: 1344 EQINKQGLEIESLKTVSHEAEVHAESLQQKLE--SSQLQIAGLEHLREL----QPKLDEL 1397
Query: 414 EKL-SKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYE---KRGHDNW-LA 468
+KL SK EE +S + QL E E + Q ++I E K H +
Sbjct: 1398 QKLISKKEEDVSYLSGQL-----------SEKEAALTKIQTEIIEQEDLIKALHTQLEMQ 1446
Query: 469 ARTAERNLSDLRKENAHNKQKLTE 492
A+ + + L+ E KQK E
Sbjct: 1447 AKEHDERIKQLQVELCEMKQKPEE 1470
Score = 50.8 bits (120), Expect = 5e-06
Identities = 88/418 (21%), Positives = 168/418 (40%), Gaps = 72/418 (17%)
Query: 62 SFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSL----IQKEYEGYEVESSLEDASF 117
S ++ R R+ VG Q+L +I EK +L+++ + +++E G + S ++D +
Sbjct: 2468 SLQNDRDRI-VGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRG--LRSHMDDLNS 2524
Query: 118 EKAAAEEARSLEATCEKLNR------------------SNSELEDEILCLEKDLKEEKSK 159
E A + L E LN+ N ELE++ LE+ LKE +
Sbjct: 2525 ENAKLDA--ELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEA 2582
Query: 160 HSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQL 219
+ + + Q L E +SLK I S+ R + AL E L
Sbjct: 2583 NEDLRRSFNALQEEKQDLSKEIESLKVSI------------SQLTRQVT---ALQEEGTL 2627
Query: 220 QTSHKQLFQQEAEVWK---------GEVSELNKQKITFEDSKVHAEQVLNDK-ENHIKTL 269
H QL +E EV + ++EL ++ + + + DK + +K L
Sbjct: 2628 GLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHL 2687
Query: 270 TGHLPMMKDQAAVLEEDTTD--DDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVS 327
+M+++ EE + D +E+E N KG ++ S
Sbjct: 2688 HHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKEN-----KGLTAQI---QSFGRS 2739
Query: 328 LKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ------QESLQSENIYF--ESENQK 379
+ SL+ R+H +L E+ + + + + L+ Q +++L SE + +E
Sbjct: 2740 MSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENS 2799
Query: 380 LQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEE--EEKLSKVEEKLSRATEQLETYRK 435
L K+ + +DE L+ +E++Y + + ++ ++ + +LE +RK
Sbjct: 2800 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2857
Score = 50.4 bits (119), Expect = 6e-06
Identities = 94/452 (20%), Positives = 188/452 (41%), Gaps = 64/452 (14%)
Query: 107 EVESSLEDASFEKAAAEEARSLEATCEKLNRSN-SELEDEILCLEKDLKEEKSKHSQQDE 165
E++ + E+ +F K + R+ EA E L++ ++E E + K +K Q
Sbjct: 565 EMKEAQEEIAFLKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIK-MKVFLEDTGQDFP 623
Query: 166 LMADISKSIQSLEDESKSLKSQ--------IAEAKIICKTFKMSEERRAIAIKDALN-EN 216
LM + S+ ++E E S + Q + +A + K+ K ++ A+ D
Sbjct: 624 LMPNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQ 683
Query: 217 SQLQTSHKQLFQQEAEVWKG-------------EVSELNKQKITFE---DSKVHAEQVLN 260
+L+ Q+ + E K E+S LN+ F+ D+ A L+
Sbjct: 684 DELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALS 743
Query: 261 DKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKL-I 319
++ + + + L M+ + A +++ + E + +E+ D+ L + L I
Sbjct: 744 EERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSI 803
Query: 320 HAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENI-------Y 372
A +V ++ L+ E + + +Q SE I++LQ+Q ++ +SE + +
Sbjct: 804 EAKSKDVKIEVLQNELDDVQLQFSEQSTL-------IRSLQSQLQNKESEVLEGAERVRH 856
Query: 373 FESENQKLQQKL-KIMTEFYQEDEMKLYRKLTVEENYRIEEE-------------EKLSK 418
S+ ++L Q L + E + D++ L +K VE + EE EK+ +
Sbjct: 857 ISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQ 916
Query: 419 V-EEKLSRAT------EQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAART 471
+ EEK S EQL + + +E++E +Y++ ++
Sbjct: 917 LNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEE 976
Query: 472 AERNLSDLRKENAHNKQKLTETEL-KFELLEK 502
+ L+KEN K+KL + + ELL++
Sbjct: 977 LQHEFDLLKKENEQRKRKLQAALINRKELLQR 1008
Score = 46.6 bits (109), Expect = 9e-05
Identities = 86/436 (19%), Positives = 194/436 (44%), Gaps = 64/436 (14%)
Query: 86 IEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDE 145
++EK K + + + +E++ +++ ++S A +EE L + ++L+ +EL +
Sbjct: 711 LDEKAKEISNLNQLIEEFK----KNADNNSSAFTALSEERDQLLSQVKELSMV-TELRAQ 765
Query: 146 ILCLEKDLKEEKSKH-------SQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
+ LE +L E + + + D L+ + S+ S+E +SK +K ++ + ++
Sbjct: 766 VKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSL-SIEAKSKDVKIEVLQNELDDVQL 824
Query: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHA-EQ 257
+ SE+ ++ +++ QL +E+EV +G +++ SKV Q
Sbjct: 825 QFSEQ------------STLIRSLQSQLQNKESEVLEGA------ERVRHISSKVEELSQ 866
Query: 258 VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVN-SQWENGANLDDPLKGALK 316
L+ KE I + L K L++ + D E++ S E L++
Sbjct: 867 ALSQKELEITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNE------- 919
Query: 317 KLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESE 376
L V +K+L+ + N LS ++ K+E E + + + E
Sbjct: 920 ---EKFSLGVEIKTLKEQLN----LLSRAEEAKKEQVEEDNEVSSGLKQNYDE---MSPA 969
Query: 377 NQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKL 436
Q +++L+ + +++ + RKL R E +++S++EE+L+ ++ + L
Sbjct: 970 GQISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPL 1029
Query: 437 AK----DLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
++ ++EE+ E Y ++ ++ + + + +L ++ +S+ E H ++ L E
Sbjct: 1030 SETERGEVEEDKENKE--YSEKCVTSKCQEIEIYL-----KQTISEKEVELQHIRKDLEE 1082
Query: 493 ---TELKFELLEKDPN 505
E +F+ L K N
Sbjct: 1083 KLAAEEQFQALVKQMN 1098
Score = 43.1 bits (100), Expect = 0.001
Identities = 70/377 (18%), Positives = 150/377 (39%), Gaps = 57/377 (15%)
Query: 133 EKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDES------KSLKS 186
E+L N +L +I LE + ++ + + DI+ S +ES +
Sbjct: 495 EELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQ 554
Query: 187 QIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKI 246
+ E ++ K ++E A +K L + H+ L Q+E + +GE K K+
Sbjct: 555 KHKELSVLLLEMKEAQEEIAF-LKLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKV 613
Query: 247 TFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGAN 306
ED+ + N++ + LP ++ + A E + + + L
Sbjct: 614 FLEDTGQDFPLMPNEESS--------LPAVEKEQASTEHQSRTSEEISLN---------- 655
Query: 307 LDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKN--LQTQQE 364
V LKS + + + + + ++ + ++ E +K+ L+ +
Sbjct: 656 ----------------DAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELN 699
Query: 365 SLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLS 424
+++ IY ++ ++K ++ + + + +E + + E ++ LS+V+E LS
Sbjct: 700 FHKAQEIYEKNLDEKAKE-ISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKE-LS 757
Query: 425 RATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAAR----TAERNLSDLR 480
TE ++L +L E + Y+ Q HDN L + + E D++
Sbjct: 758 MVTELRAQVKQLEMNLAEAERQRRLDYESQT------AHDNLLTEQIHSLSIEAKSKDVK 811
Query: 481 KENAHNKQKLTETELKF 497
E N +L + +L+F
Sbjct: 812 IEVLQN--ELDDVQLQF 826
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 74.3 bits (181), Expect = 4e-13
Identities = 97/475 (20%), Positives = 198/475 (41%), Gaps = 66/475 (13%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARS-LEATCE 133
E K A L+ L ++ +L+ + + E L+ +K AE+A + L+ +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELT---------EKTGKLQQEEVQKKNAEQAATQLKVQLQ 491
Query: 134 KLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
+ R E++ I + + ++ + D+ + E+E +SL S++ + +
Sbjct: 492 EAERRWEEVQSYI----------RKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLV 541
Query: 194 ICKTFKMSEERRAIAIKDA----LNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFE 249
K E+R + + ++ +N+ LQ + + +Q E K ++ + + Q
Sbjct: 542 S----KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN-EALKAQIQQFHSQIAAQT 596
Query: 250 DSKVHAEQ---VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGAN 306
+ V AE+ V+ +K+ IK L +D+ EE+ D N+
Sbjct: 597 SASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL---------- 646
Query: 307 LDDPLKGALKKLIHAAKLNVSLK-SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQES 365
LK ++KL A + LE + + ++ ++ +E+L I N + +
Sbjct: 647 ----LKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702
Query: 366 LQSENIYFESENQKLQ---------QKLKIMTEFYQEDEMKLYRKLTVEENYRIE---EE 413
L +N +SE QKLQ ++ M + QE + KL + E I+ +E
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKE 762
Query: 414 EKLSKVEEKLSRATEQLETYRKLAKD------LEEELERTVHFYQKQVISYEKRGHDNWL 467
E+L+ + + S T++++ + D L EEL++ +H ++ S E+ L
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELL 822
Query: 468 AARTAERNLSDLRKENAHNKQKLTETEL-KFELLEKDPNALDVSNTAFGREHAPN 521
E+ + DL++E K+++ +L K + L ++ N G+E N
Sbjct: 823 KVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMN 877
Score = 65.1 bits (157), Expect = 2e-10
Identities = 80/383 (20%), Positives = 170/383 (44%), Gaps = 38/383 (9%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEK--AAAEEARSLEAT 131
+++++ T L E+ +L K ++E + + + L A +K A A E +
Sbjct: 612 KDKQIKQTEDSLASERDRLTSK----EEELKDIQNMNFLLKAEVQKLQALANEQAAAAHE 667
Query: 132 CEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEA 191
EK+ +S +D+I LE+ L+ E S ++ +++ D +K+++S + ++L S+
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNK 727
Query: 192 KIICKTFKMSEER-RAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQ------ 244
++ + K +E+ + + L E +Q + K ++E + E S L K+
Sbjct: 728 DVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK---EEELNAIRTENSSLTKEVQDLKA 784
Query: 245 ----KITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
+++F ++V+++K+ IK++ L + A E+ D L+ E+ +
Sbjct: 785 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQD---LKQEIKAL 841
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
E N+ L +L LK E + N + L E +K + +++LQ
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
+ ESL++ + Q LK + Q +E+++ K E+E +L ++E
Sbjct: 902 EENESLKAH------VQEVAQHNLKEASSASQFEELEIVLK---------EKENELKRLE 946
Query: 421 EKLSRATEQLETYRKLAKDLEEE 443
L L + +L +D+++E
Sbjct: 947 AMLKERESDLSSKTQLLQDVQDE 969
Score = 59.7 bits (143), Expect = 1e-08
Identities = 82/389 (21%), Positives = 171/389 (43%), Gaps = 44/389 (11%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT--C 132
+Q+L L L+E + K + K +Q + + ++ A ++ ++ A A+
Sbjct: 543 KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA 602
Query: 133 EKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAK 192
E+L++ +E + +I E L E+ + + ++E + DI L+ E + L++ E
Sbjct: 603 EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQA 662
Query: 193 IICKTFKMSEERRAIAIKD----ALNENSQLQTSHK----QLFQQEAEVWKGEVSELNK- 243
++ + ++++ +KD L E Q + S+K ++ + + K EV +L
Sbjct: 663 --AAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTL 720
Query: 244 -QKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDT----TDDDNLELEVN 298
+ +D E+ + +K+ +KT+ L Q A EE+ T++ +L EV
Sbjct: 721 VSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ 780
Query: 299 S--QWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHI 356
+N L LKK+IH + + +KS+E +++++ +KT ++L + I
Sbjct: 781 DLKAKQNDQVSFASLVEELKKVIH--EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEI 838
Query: 357 KNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKL 416
K L+ + ++Q E S K+Q+ +N +EE++
Sbjct: 839 KALKEEIGNVQLEKAQQLSITSKVQEL----------------------QNLLKGKEEQM 876
Query: 417 SKVEEKLSRATEQLETYRKLAKDLEEELE 445
+ ++ L + L K +DL+EE E
Sbjct: 877 NTMKAVLEEKEKDLANTGKWLQDLQEENE 905
Score = 58.5 bits (140), Expect = 2e-08
Identities = 83/367 (22%), Positives = 147/367 (40%), Gaps = 46/367 (12%)
Query: 143 EDEILCLEKDLKEEKS--KHSQQDELMADISKSIQSLEDESKSL---KSQIAEAKIICKT 197
EDE LC+ LKE+ + + + +++ I L+++ K L K A K CK
Sbjct: 298 EDEALCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQ 357
Query: 198 FK---MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVH 254
M+E+ R+ + + + +FQ + V E ++ ++
Sbjct: 358 LTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQM----------QMK 407
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGA 314
+QV E I L +++D AV + E+N ++ A L + L
Sbjct: 408 FQQVREQMEAEIAHLKQENGILRD--AVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 315 LKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ----QESLQSEN 370
KL + V K+ E + +QL E ++ EE+ +I+ + Q+ LQS+
Sbjct: 466 TGKL---QQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKF 522
Query: 371 IYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQL 430
+ E+E Q L KL Q+ E +L +L E R+ +EE L + + E L
Sbjct: 523 VAKENEVQSLHSKLTDTLVSKQQLEQRL-MQLMESEQKRVNKEESLQMQVQDILEQNEAL 581
Query: 431 ETY----------RKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAAR----TAERNL 476
+ + A L EEL + + KQ+ K+ D+ + R + E L
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQI----KQTEDSLASERDRLTSKEEEL 637
Query: 477 SDLRKEN 483
D++ N
Sbjct: 638 KDIQNMN 644
Score = 53.5 bits (127), Expect = 7e-07
Identities = 105/456 (23%), Positives = 190/456 (41%), Gaps = 79/456 (17%)
Query: 70 LYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLE 129
L G+E+++ T+ ++EEK K L K + + E+ A ++ A +
Sbjct: 868 LLKGKEEQMN-TMKAVLEEKEKDLANTG---KWLQDLQEENESLKAHVQEVAQHNLKEAS 923
Query: 130 ATC--EKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQ 187
+ E+L E E+E+ LE LKE +S S + +L+ D+ +DE+K KSQ
Sbjct: 924 SASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDV-------QDENKLFKSQ 976
Query: 188 IAEAKIICKTFKMSEERRAIAIKDALNENSQLQTS---HKQLFQQEAEVWKGEVSELNKQ 244
I + K +N Q +S H++L + +E K E+S L +
Sbjct: 977 IEQLK---------------------QQNYQQASSFPPHEELLKVISEREK-EISGLWNE 1014
Query: 245 KITFEDSKVHAEQVLNDKENH----IKTLTGHLPMMKDQA-AVLEEDTTDDDNLELEVN- 298
+ +D+ H + ND ++ L M++D+ +E + +ELE
Sbjct: 1015 LDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKE 1074
Query: 299 -----------------SQWENGANLDDPLKGALKKLIHAAKLNV-SLKSLEGERNHIII 340
+W +G + K + + ++ V K E + H ++
Sbjct: 1075 VLKKLFPKVSVPSNLSYGEWLHG--FEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLL 1132
Query: 341 QLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYR 400
QL E +K K L E LQ Q S++ E ++ + + + +K M + E +L R
Sbjct: 1133 QL-ECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER 1191
Query: 401 KLTVE---ENYRIEEEE---KLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQ 454
+ EN R E E +L K E + S ++ + L +L+++L+ + Y +
Sbjct: 1192 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDS---YSEA 1248
Query: 455 VISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKL 490
V E+ N L A+ E L+ LR E + +QK+
Sbjct: 1249 VRQNEEL---NLLKAQLNE-TLTKLRTEQ-NERQKV 1279
Score = 32.0 bits (71), Expect = 2.3
Identities = 31/143 (21%), Positives = 66/143 (46%), Gaps = 9/143 (6%)
Query: 99 IQKEYEGYEVESSL---EDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKE 155
++ E E E+E S E + E + L+ + + R N EL L + L +
Sbjct: 1209 LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTK 1268
Query: 156 EKSKHSQQDELMADISKSIQSLE-DESKSLKSQ-----IAEAKIICKTFKMSEERRAIAI 209
+++ +++ ++ D+ K+ QSLE +SK +K+ I + + +T +E ++++
Sbjct: 1269 LRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSL 1328
Query: 210 KDALNENSQLQTSHKQLFQQEAE 232
+ + QL + Q +E E
Sbjct: 1329 NQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 74.3 bits (181), Expect = 4e-13
Identities = 97/475 (20%), Positives = 198/475 (41%), Gaps = 66/475 (13%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARS-LEATCE 133
E K A L+ L ++ +L+ + + E L+ +K AE+A + L+ +
Sbjct: 441 ESKQSAELNKLRQDYARLVNELT---------EKTGKLQQEEVQKKNAEQAATQLKVQLQ 491
Query: 134 KLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
+ R E++ I + + ++ + D+ + E+E +SL S++ + +
Sbjct: 492 EAERRWEEVQSYI----------RKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLV 541
Query: 194 ICKTFKMSEERRAIAIKDA----LNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFE 249
K E+R + + ++ +N+ LQ + + +Q E K ++ + + Q
Sbjct: 542 S----KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN-EALKAQIQQFHSQIAAQT 596
Query: 250 DSKVHAEQ---VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGAN 306
+ V AE+ V+ +K+ IK L +D+ EE+ D N+
Sbjct: 597 SASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFL---------- 646
Query: 307 LDDPLKGALKKLIHAAKLNVSLK-SLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQES 365
LK ++KL A + LE + + ++ ++ +E+L I N + +
Sbjct: 647 ----LKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702
Query: 366 LQSENIYFESENQKLQ---------QKLKIMTEFYQEDEMKLYRKLTVEENYRIE---EE 413
L +N +SE QKLQ ++ M + QE + KL + E I+ +E
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKE 762
Query: 414 EKLSKVEEKLSRATEQLETYRKLAKD------LEEELERTVHFYQKQVISYEKRGHDNWL 467
E+L+ + + S T++++ + D L EEL++ +H ++ S E+ L
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELL 822
Query: 468 AARTAERNLSDLRKENAHNKQKLTETEL-KFELLEKDPNALDVSNTAFGREHAPN 521
E+ + DL++E K+++ +L K + L ++ N G+E N
Sbjct: 823 KVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMN 877
Score = 65.1 bits (157), Expect = 2e-10
Identities = 80/383 (20%), Positives = 170/383 (44%), Gaps = 38/383 (9%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEK--AAAEEARSLEAT 131
+++++ T L E+ +L K ++E + + + L A +K A A E +
Sbjct: 612 KDKQIKQTEDSLASERDRLTSK----EEELKDIQNMNFLLKAEVQKLQALANEQAAAAHE 667
Query: 132 CEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEA 191
EK+ +S +D+I LE+ L+ E S ++ +++ D +K+++S + ++L S+
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNK 727
Query: 192 KIICKTFKMSEER-RAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQ------ 244
++ + K +E+ + + L E +Q + K ++E + E S L K+
Sbjct: 728 DVVEQMEKCIQEKDEKLKTVEELLETGLIQVATK---EEELNAIRTENSSLTKEVQDLKA 784
Query: 245 ----KITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQ 300
+++F ++V+++K+ IK++ L + A E+ D L+ E+ +
Sbjct: 785 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQD---LKQEIKAL 841
Query: 301 WENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQ 360
E N+ L +L LK E + N + L E +K + +++LQ
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 361 TQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVE 420
+ ESL++ + Q LK + Q +E+++ K E+E +L ++E
Sbjct: 902 EENESLKAH------VQEVAQHNLKEASSASQFEELEIVLK---------EKENELKRLE 946
Query: 421 EKLSRATEQLETYRKLAKDLEEE 443
L L + +L +D+++E
Sbjct: 947 AMLKERESDLSSKTQLLQDVQDE 969
Score = 59.7 bits (143), Expect = 1e-08
Identities = 82/389 (21%), Positives = 171/389 (43%), Gaps = 44/389 (11%)
Query: 75 EQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT--C 132
+Q+L L L+E + K + K +Q + + ++ A ++ ++ A A+
Sbjct: 543 KQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLA 602
Query: 133 EKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAK 192
E+L++ +E + +I E L E+ + + ++E + DI L+ E + L++ E
Sbjct: 603 EELHKVIAEKDKQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQA 662
Query: 193 IICKTFKMSEERRAIAIKD----ALNENSQLQTSHK----QLFQQEAEVWKGEVSELNK- 243
++ + ++++ +KD L E Q + S+K ++ + + K EV +L
Sbjct: 663 --AAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTL 720
Query: 244 -QKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDT----TDDDNLELEVN 298
+ +D E+ + +K+ +KT+ L Q A EE+ T++ +L EV
Sbjct: 721 VSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQ 780
Query: 299 S--QWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHI 356
+N L LKK+IH + + +KS+E +++++ +KT ++L + I
Sbjct: 781 DLKAKQNDQVSFASLVEELKKVIH--EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEI 838
Query: 357 KNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKL 416
K L+ + ++Q E S K+Q+ +N +EE++
Sbjct: 839 KALKEEIGNVQLEKAQQLSITSKVQEL----------------------QNLLKGKEEQM 876
Query: 417 SKVEEKLSRATEQLETYRKLAKDLEEELE 445
+ ++ L + L K +DL+EE E
Sbjct: 877 NTMKAVLEEKEKDLANTGKWLQDLQEENE 905
Score = 58.5 bits (140), Expect = 2e-08
Identities = 83/367 (22%), Positives = 147/367 (40%), Gaps = 46/367 (12%)
Query: 143 EDEILCLEKDLKEEKS--KHSQQDELMADISKSIQSLEDESKSL---KSQIAEAKIICKT 197
EDE LC+ LKE+ + + + +++ I L+++ K L K A K CK
Sbjct: 298 EDEALCVVDLLKEKSGVIQDALKKSSKGELTTLIHQLQEKDKLLAAVKEDAAATKDRCKQ 357
Query: 198 FK---MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVH 254
M+E+ R+ + + + +FQ + V E ++ ++
Sbjct: 358 LTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQM----------QMK 407
Query: 255 AEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGA 314
+QV E I L +++D AV + E+N ++ A L + L
Sbjct: 408 FQQVREQMEAEIAHLKQENGILRD--AVSNTTNQLESKQSAELNKLRQDYARLVNELTEK 465
Query: 315 LKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ----QESLQSEN 370
KL + V K+ E + +QL E ++ EE+ +I+ + Q+ LQS+
Sbjct: 466 TGKL---QQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKF 522
Query: 371 IYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQL 430
+ E+E Q L KL Q+ E +L +L E R+ +EE L + + E L
Sbjct: 523 VAKENEVQSLHSKLTDTLVSKQQLEQRL-MQLMESEQKRVNKEESLQMQVQDILEQNEAL 581
Query: 431 ETY----------RKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAAR----TAERNL 476
+ + A L EEL + + KQ+ K+ D+ + R + E L
Sbjct: 582 KAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQI----KQTEDSLASERDRLTSKEEEL 637
Query: 477 SDLRKEN 483
D++ N
Sbjct: 638 KDIQNMN 644
Score = 53.5 bits (127), Expect = 7e-07
Identities = 105/456 (23%), Positives = 190/456 (41%), Gaps = 79/456 (17%)
Query: 70 LYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLE 129
L G+E+++ T+ ++EEK K L K + + E+ A ++ A +
Sbjct: 868 LLKGKEEQMN-TMKAVLEEKEKDLANTG---KWLQDLQEENESLKAHVQEVAQHNLKEAS 923
Query: 130 ATC--EKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQ 187
+ E+L E E+E+ LE LKE +S S + +L+ D+ +DE+K KSQ
Sbjct: 924 SASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDV-------QDENKLFKSQ 976
Query: 188 IAEAKIICKTFKMSEERRAIAIKDALNENSQLQTS---HKQLFQQEAEVWKGEVSELNKQ 244
I + K +N Q +S H++L + +E K E+S L +
Sbjct: 977 IEQLK---------------------QQNYQQASSFPPHEELLKVISEREK-EISGLWNE 1014
Query: 245 KITFEDSKVHAEQVLNDKENH----IKTLTGHLPMMKDQA-AVLEEDTTDDDNLELEVN- 298
+ +D+ H + ND ++ L M++D+ +E + +ELE
Sbjct: 1015 LDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKE 1074
Query: 299 -----------------SQWENGANLDDPLKGALKKLIHAAKLNV-SLKSLEGERNHIII 340
+W +G + K + + ++ V K E + H ++
Sbjct: 1075 VLKKLFPKVSVPSNLSYGEWLHG--FEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLL 1132
Query: 341 QLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYR 400
QL E +K K L E LQ Q S++ E ++ + + + +K M + E +L R
Sbjct: 1133 QL-ECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELER 1191
Query: 401 KLTVE---ENYRIEEEE---KLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQ 454
+ EN R E E +L K E + S ++ + L +L+++L+ + Y +
Sbjct: 1192 LRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDS---YSEA 1248
Query: 455 VISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKL 490
V E+ N L A+ E L+ LR E + +QK+
Sbjct: 1249 VRQNEEL---NLLKAQLNE-TLTKLRTEQ-NERQKV 1279
Score = 32.0 bits (71), Expect = 2.3
Identities = 31/143 (21%), Positives = 66/143 (46%), Gaps = 9/143 (6%)
Query: 99 IQKEYEGYEVESSL---EDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKE 155
++ E E E+E S E + E + L+ + + R N EL L + L +
Sbjct: 1209 LEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEELNLLKAQLNETLTK 1268
Query: 156 EKSKHSQQDELMADISKSIQSLE-DESKSLKSQ-----IAEAKIICKTFKMSEERRAIAI 209
+++ +++ ++ D+ K+ QSLE +SK +K+ I + + +T +E ++++
Sbjct: 1269 LRTEQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSVSL 1328
Query: 210 KDALNENSQLQTSHKQLFQQEAE 232
+ + QL + Q +E E
Sbjct: 1329 NQTVTQLQQLLQAVNQQLTKEKE 1351
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 74.3 bits (181), Expect = 4e-13
Identities = 80/437 (18%), Positives = 189/437 (43%), Gaps = 46/437 (10%)
Query: 94 EKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEIL---CLE 150
E LI + ++ ++ LE A A A + + + E+L + L E+ +
Sbjct: 147 EARDLISRLHDSWKFAGELEQAL--SAVATQKKKADRYIEELTKERDALSLELYRNTITD 204
Query: 151 KDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIK 210
++LKE+ +K ++ +L+ IQ K LK ++ AK++ ++ E + +
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQL---NVKELKRKLERAKLLLPQQQLQAEADHLGKE 261
Query: 211 -DALNENSQLQTSHKQLF-----QQEAEVWKGEVS-ELNKQKITFEDSKVHA-------- 255
+++ Q Q +L+ QQE ++W+ E + ++KI ++ K+
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 256 EQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGAL 315
E+++ +KE ++ + +++ LEE + + + + + E ++ ++
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE-----EEKIREQE 376
Query: 316 KKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFES 375
K+ AK+ + + + I Q + + +E++ E + + Q+E +Q +
Sbjct: 377 KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 376 ENQKL----------QQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSR 425
+ +K+ ++K++ E QE E K+ +E E+E K+ + EEK+ R
Sbjct: 437 QEEKIREQEKKIREQEEKIREQEEMMQEQE----EKMGEQEGKMCEQEAKMQEQEEKMRR 492
Query: 426 ATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAH 485
E++ K ++ EE++ Q+Q E++ + E + + ++
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQ----EEKMWEQEEKMCEQEEKMQEQEEKMRR 548
Query: 486 NKQKLTETELKFELLEK 502
++K+ E E++ E+
Sbjct: 549 QEEKMREQEVRLRQQEE 565
Score = 67.4 bits (163), Expect = 5e-11
Identities = 78/393 (19%), Positives = 171/393 (43%), Gaps = 63/393 (16%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGY-----EVESSLEDASF-------EKAAAEEARSLEATC 132
L E+ KL EK L++ E E++ LE A + A + L++
Sbjct: 207 LKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVS 266
Query: 133 EKL----------NRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLED--- 179
KL NR N + E+++ E+ ++E + K +Q+E + + + ++ E+
Sbjct: 267 AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMW 326
Query: 180 --ESKSLKSQIA----EAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEV 233
E K + + E KI KM E+ + ++ E +++ K+ +QEA++
Sbjct: 327 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ-EQEAKM 385
Query: 234 WKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL 293
W+ E +KI ++ K+ ++ MM++Q + E
Sbjct: 386 WRQE------EKIREQEEKIREQE----------------EMMQEQEEKMGEQEEKMWEQ 423
Query: 294 ELEVNSQWENGANLDDPLKGALKKLIHAA-KLNVSLKSLEGERNHIIIQLSEVDKTKEEL 352
E E+ Q E ++ ++ KK+ K+ + ++ + + Q ++ + + ++
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483
Query: 353 TEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEE 412
E + ++ Q+E ++ + E + ++ ++K++ E QE E K++ +E E+
Sbjct: 484 QEQEEKMRRQEEKIREQ----EKKIREQEEKIREQEEMMQEQEEKMWE----QEEKMCEQ 535
Query: 413 EEKLSKVEEKLSRATEQLETYRKLAKDLEEELE 445
EEK+ + EEK+ R E++ + EE+++
Sbjct: 536 EEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 52.4 bits (124), Expect = 2e-06
Identities = 61/325 (18%), Positives = 152/325 (46%), Gaps = 25/325 (7%)
Query: 71 YVGRE-QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLE 129
++G+E Q + A L +EE +L + + Q+E + + E +++ E+ E+ +
Sbjct: 257 HLGKELQSVSAKLQAQVEEN-ELWNRLNQ-QQEEKMWRQEEKIQER--EEKIQEQEEKIR 312
Query: 130 ATCEKLNRSNS---ELEDEILCLEKDLKEEKSKHSQQDELMAD---ISKSIQSLEDESK- 182
EK+ R E E+++ E+ + E++ K + +E M + I + + ++E K
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 372
Query: 183 --SLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVS- 239
K Q EAK+ + K+ E+ I + +Q +++ +QE ++W+ E
Sbjct: 373 REQEKRQEQEAKMWRQEEKIREQEEKIR-----EQEEMMQEQEEKMGEQEEKMWEQEEEM 427
Query: 240 ELNKQKITFEDSKVHA-EQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVN 298
+ ++K+ ++ K+ E+ + ++E I+ MM++Q + E E ++
Sbjct: 428 QEQEEKMRRQEEKIREQEKKIREQEEKIREQE---EMMQEQEEKMGEQEGKMCEQEAKMQ 484
Query: 299 SQWENGANLDDPLKGALKKLIHAA-KLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIK 357
Q E ++ ++ KK+ K+ + ++ + + Q ++ + +E++ E +
Sbjct: 485 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 544
Query: 358 NLQTQQESLQSENIYFESENQKLQQ 382
++ Q+E ++ + + + +K+Q+
Sbjct: 545 KMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 47.8 bits (112), Expect = 4e-05
Identities = 71/386 (18%), Positives = 160/386 (41%), Gaps = 70/386 (18%)
Query: 160 HSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQL 219
HS +DE A S Q E + L++Q+ +I+ T + +E + A+ + QL
Sbjct: 93 HSPEDEQKA----SHQHQEALRRELEAQVQTIRIL--TCQKTELQMALYYSQ--HAVKQL 144
Query: 220 QTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLND--KENHIKTLTGHLPMMK 277
+ + L + + WK EL + K A++ + + KE +L + +
Sbjct: 145 EGEARDLISRLHDSWKF-AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 203
Query: 278 DQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNH 337
D+ + E++ + L+L + + E N+ + LK+ + AKL + + L+ E +H
Sbjct: 204 DEE-LKEKNAKLQEKLQLVESEKSEIQLNVKE-----LKRKLERAKLLLPQQQLQAEADH 257
Query: 338 IIIQLSEVD-------------------------KTKEELTEHIKNLQTQQESLQS---- 368
+ +L V + +E++ E + +Q Q+E ++
Sbjct: 258 LGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEK 317
Query: 369 ------------------ENIYFESENQ--KLQQKLKIMTEFYQEDEMKLYRKLTVEENY 408
E + +E E + +L++K+ + +++E + + E+
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 377
Query: 409 RIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLA 468
R E+E K+ + EEK+ E++ ++ ++ EE++ ++++ E+ +
Sbjct: 378 RQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGE----QEEKMWEQEEEMQEQEEK 433
Query: 469 ARTAERNLSDLRKENAHNKQKLTETE 494
R E + + K+ ++K+ E E
Sbjct: 434 MRRQEEKIREQEKKIREQEEKIREQE 459
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 73.2 bits (178), Expect = 9e-13
Identities = 85/458 (18%), Positives = 198/458 (43%), Gaps = 63/458 (13%)
Query: 71 YVGRE-QKLGATLSGLIEE-----KCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEE 124
++G+E Q + A L +EE + ++ + ++E + E E +++ E+ E+
Sbjct: 269 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ--EEKIREQ 326
Query: 125 ARSLEATCEKLNRSNS---ELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDES 181
+ EK+ R E E+++ E+ + E++ K +Q+E+M + + ++ E+
Sbjct: 327 EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM 386
Query: 182 KSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSEL 241
+ +I E + KM E+ + ++ E +++ K+ +QEA++W+ E
Sbjct: 387 WEKEEKIRELEE-----KMHEQEKIREQEEKRQEEEKIREQEKRQ-EQEAKMWRQE---- 436
Query: 242 NKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQW 301
+KI ++ K+ ++ M + + + E++ ++ E W
Sbjct: 437 --EKIREQEEKIREQEK---------------KMWRQEEKIHEQEKIREEEKRQEQEEMW 479
Query: 302 ENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQT 361
+ + + +K K++ + + + + Q ++ + +E++ E + +
Sbjct: 480 RQEEKIHEQEEIWRQK----EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR 535
Query: 362 QQESL--------------QSENIYFESENQKLQQKLKIMTEFYQEDEMKLYR---KLTV 404
Q+E + + E I+ E + Q+ + K+ E +E E K++R K+
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIRE 595
Query: 405 EENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHD 464
+E R E+EEK+ K EEK+ E+++ + ++ EE++ Q+Q EK G
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ---EEKMGEQ 652
Query: 465 NWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEK 502
E+ + + + ++K+ E E K E+
Sbjct: 653 EEKMCEQEEK-MQEQEETMWRQEEKIREQEKKIREQEE 689
Score = 68.9 bits (167), Expect = 2e-11
Identities = 80/442 (18%), Positives = 194/442 (43%), Gaps = 28/442 (6%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE 133
+E+K+ + E++ K+ + ++ ++ E + + EK +E E E
Sbjct: 319 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE-E 377
Query: 134 KLNRSNS---ELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAE 190
K+ R E E++I LE+ + E++ K +Q+E + K + + + + K E
Sbjct: 378 KMRRQEEMMWEKEEKIRELEEKMHEQE-KIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 436
Query: 191 AKIICKTFKMSE-ERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFE 249
KI + K+ E E++ ++ ++E +++ K+ Q++ E+W+ E +++I +
Sbjct: 437 EKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR--QEQEEMWRQEEKIHEQEEIWRQ 494
Query: 250 DSKVHA-EQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLD 308
K+H E+ + +E + + +++ EE + E W +
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 309 DPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQS 368
+ +K+ K + + I Q +V + +E++ E + Q Q+E +
Sbjct: 555 EQ-----EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 369 ENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRI--------EEEEKLSKVE 420
+ + +K+Q++ + + E QE++++ ++T E+ ++ E+EEK+ + E
Sbjct: 610 QEEKIREQEEKIQEQEEKIRE--QEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667
Query: 421 EKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLR 480
E + R E++ K ++ EE++ Q+Q E++ + E + +
Sbjct: 668 ETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQ----EEKMWEQEEKMCEQEEKMQEQE 723
Query: 481 KENAHNKQKLTETELKFELLEK 502
++ ++K+ E E++ E+
Sbjct: 724 EKMRRQEEKMWEQEVRLRQQEE 745
Score = 64.3 bits (155), Expect = 4e-10
Identities = 67/386 (17%), Positives = 173/386 (44%), Gaps = 40/386 (10%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASF----EKAAAEEARSLE 129
+E+K+ L + E+ K+ E+ Q+E + E E E + E+ E+ +
Sbjct: 389 KEEKI-RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 447
Query: 130 ATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELM---ADISKSIQSLEDESKSLKS 186
+K+ R ++ ++ E++ ++E+ + +Q+E + +I + + + ++ + ++
Sbjct: 448 EQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRK 507
Query: 187 QIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKI 246
Q E K+ + K+ E+ ++ + E + ++ +++ E+W+ E ++KI
Sbjct: 508 Q--EEKVWRQEEKIREQ------EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Query: 247 TFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL----ELEVNSQWE 302
E+ + E + +E I+ + +++ EE + + E ++ Q E
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 303 NGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ 362
++ ++ +K+ ++ + GE+ +E++ E + +Q Q
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ-------------EEKMCEQEEKMQEQ 666
Query: 363 QESLQSENIYFESENQKL---QQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKV 419
+E++ + + +K+ ++K++ E QE E K++ +E E+EEK+ +
Sbjct: 667 EETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE----QEEKMCEQEEKMQEQ 722
Query: 420 EEKLSRATEQLETYRKLAKDLEEELE 445
EEK+ R E++ + EE+++
Sbjct: 723 EEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 56.6 bits (135), Expect = 9e-08
Identities = 85/350 (24%), Positives = 157/350 (44%), Gaps = 43/350 (12%)
Query: 160 HSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQL 219
HS +DE A S Q E + L++Q+ +I+ T + +E + A+ + QL
Sbjct: 105 HSPEDEQKA----SHQHQEALRRELEAQVHTIRIL--TCQKTELQMALYYSQ--HAVKQL 156
Query: 220 QTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLND--KENHIKTLTGHLPMMK 277
+ + L + + WK EL + K A++ + + KE +L + +
Sbjct: 157 EGEARDLISRLHDSWKF-AGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTIT 215
Query: 278 DQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNH 337
D+ + E++ + L+L + + E N+ + LK+ + AKL + + L+ E +H
Sbjct: 216 DEE-LKEKNAKLQEKLQLVESEKSEIQLNVKE-----LKRKLERAKLLLPQQQLQAEADH 269
Query: 338 IIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMK 397
+ +L V LQ Q E EN + NQ+ ++K+ E QE E K
Sbjct: 270 LGKELQSVSA----------KLQAQVE----ENELWNRLNQQQEEKMWRQEEKIQEWEEK 315
Query: 398 LYRKLTVEENYRIEEEEKLSKVEEKLSRATEQL-ETYRKLAKDLEEELERTVHFYQKQVI 456
+ + EE R E+EEK+ + EEK+ R E + E K+ + E E+ +++ +
Sbjct: 316 IQEQ---EEKIR-EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 371
Query: 457 SYEK----RGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEK 502
+EK R + + + E + +L +E H ++K+ E E K + EK
Sbjct: 372 MWEKEEKMRRQEEMMWEK--EEKIREL-EEKMHEQEKIREQEEKRQEEEK 418
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 73.2 bits (178), Expect = 9e-13
Identities = 96/442 (21%), Positives = 189/442 (42%), Gaps = 52/442 (11%)
Query: 85 LIEEKCKLLEKFSLIQKEY-EGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELE 143
L ++ +L +K ++E+ E +V + + K + E+ + E+L +
Sbjct: 489 LARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIL 548
Query: 144 DEILCLEKDLKEEKSKHSQQD-ELMADISKSIQSLEDESKSLKSQI-AEAKIICKTFKMS 201
E +DL++E + + EL + + KS+Q +++SK L + AE K +
Sbjct: 549 TESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVM 608
Query: 202 EERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQK--ITFEDSKV----HA 255
E+ ++ ++ L T Q+ +Q+ + ++ E +Q+ +D ++ H
Sbjct: 609 VEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHI 668
Query: 256 EQV-------LNDKENHIKTLTGHLPMMKDQAAVLEE------DTTDDDNLELEVNSQWE 302
E++ L+ K+ +++L+ L + LEE D TD ELE E
Sbjct: 669 EEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMD-E 727
Query: 303 NGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQ 362
+ + +K+ H + + K+L+ + N + + L E DK H+K Q
Sbjct: 728 QKNHHQQQVDSIIKE--HEVSIQRTEKALKDQINQLELLLKERDK-------HLKEHQAH 778
Query: 363 QESLQSENIYFESENQKLQQKLKIM----------TEFYQEDEMKLYRKLTVEENYRIEE 412
E+L+++ E E Q+ KL + T+ Y+E +L +KL E RI
Sbjct: 779 VENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILL 838
Query: 413 EEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTA 472
+++++VE + +L+ ++ +DL ++LE+ +++V S +
Sbjct: 839 TKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKS----------LTQVY 888
Query: 473 ERNLSDLRKENAHNKQKLTETE 494
E L D KE KQ L E E
Sbjct: 889 ESKLEDGNKEQEQTKQILVEKE 910
Score = 66.6 bits (161), Expect = 8e-11
Identities = 95/447 (21%), Positives = 203/447 (45%), Gaps = 52/447 (11%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE 133
REQK + + EE K L ++ + E + + EK + EE SL+ +
Sbjct: 402 REQKEKSERAAF-EELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQ---Q 457
Query: 134 KLNRSNSEL--------EDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLK 185
+L+R E+ E++I L+K ++E ++ Q+ ++K +Q+ E E + +
Sbjct: 458 ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQE------LTKKLQTREREFQE-Q 510
Query: 186 SQIAEAKIICKTFKMSEERR---AIAIKDA-LNENSQLQTSHKQL--FQQEAEVWKGEVS 239
++A K + K+S+E+ ++A+++ L + + L S +L QQEAE ++ +
Sbjct: 511 MKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRIL 570
Query: 240 ELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQ-----AAVLEEDTTDDDNLE 294
EL E+ L + +N K L HL K++ ++E+ T+ ++L+
Sbjct: 571 ELESS----------LEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLK 620
Query: 295 LEVNSQW-ENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELT 353
+ ++ W E L + ++KL K ++L ++ II + +++ E+
Sbjct: 621 HQQDALWTEKLQVLKQQYQTEMEKL--REKCEQEKETLLKDKE--IIFQAHIEEMNEKTL 676
Query: 354 EHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEE 413
E + QT+ ESL SE KL+++L ++ + + + +L K+ ++N+ ++
Sbjct: 677 EKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQV 736
Query: 414 EKLSKVEEKLSRATE-----QLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLA 468
+ + K E + TE Q+ L K+ ++ L+ H + + + + + L
Sbjct: 737 DSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKE--HQAHVENLEADIKRSEGELQ 794
Query: 469 ARTAERNLSDLRKENAHNKQKLTETEL 495
+A+ ++ + H + K E +L
Sbjct: 795 QASAKLDVFQSYQSATHEQTKAYEEQL 821
Score = 66.6 bits (161), Expect = 8e-11
Identities = 99/485 (20%), Positives = 204/485 (42%), Gaps = 71/485 (14%)
Query: 77 KLGATLSGLIEEKCKLLEKFS-----LIQKEYEGYEVESSLEDASFEKAAAEE------- 124
+L A L L EE+ L F L +KE + +++ +E EK A ++
Sbjct: 1273 ELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQ 1332
Query: 125 -ARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKS 183
A E+ +L + SE + + ++++LKE+K + S + + D++ +Q+ S S
Sbjct: 1333 AASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN----SIS 1388
Query: 184 LKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQ--QEAEVWKGEVSEL 241
L + A + K + +E + + + + ++ T K+ ++ + W + SE
Sbjct: 1389 LSEKEAAISSLRKQY---DEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEW 1445
Query: 242 NKQ---KITFEDSKVHAEQV--------LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDD 290
K+ + T + V Q+ +K+ I L L + L+ + DD
Sbjct: 1446 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDD 1505
Query: 291 --------DNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERN----HI 338
NLE E+ SQ L+D + +K I LN LK+ +++ +
Sbjct: 1506 KSKMEKKESNLETELKSQTARIMELEDHIT---QKTIEIESLNEVLKNYNQQKDIEHKEL 1562
Query: 339 IIQLSEVDKTKEELTEHIKN------------------LQTQQESLQSENIYFESENQKL 380
+ +L + EE +K L+T+++ L+ N+ +S+ ++L
Sbjct: 1563 VQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEEL 1622
Query: 381 QQKLKIMTEFYQEDEMKLYR-KLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKD 439
+ + E KL K E+ +++ LS++EEK + + E++
Sbjct: 1623 KA---LEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNT 1679
Query: 440 LEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTET-ELKFE 498
+E ER VH ++++ S E + + R+A+ + +E A ++ + +T E K
Sbjct: 1680 KLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKIS 1739
Query: 499 LLEKD 503
+L+++
Sbjct: 1740 VLQRN 1744
Score = 61.2 bits (147), Expect = 3e-09
Identities = 102/445 (22%), Positives = 185/445 (41%), Gaps = 58/445 (13%)
Query: 89 KCKLLEKFSLIQKEYEGYEVESSLEDASF-----EKAAAEEARSLEATCEKLNRSNSELE 143
K KLL++ + ++KE E +E S ++ F E A A A +A ++E
Sbjct: 971 KKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIE 1030
Query: 144 DEILCLEKDLKE-----EKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTF 198
++L + EK + Q +EL +Q E E LK +I C+
Sbjct: 1031 SLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKI--LLFGCEKE 1088
Query: 199 KMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQV 258
+M++E + ++ + +++ L +QL Q+ A V N K H E++
Sbjct: 1089 EMNKEITWLK-EEGVKQDTTLNELQEQLKQKSAHV--------NSLAQDETKLKAHLEKL 1139
Query: 259 LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKL 318
D +K T +++Q L+ +D E+ S+ + LK + +K
Sbjct: 1140 EVDLNKSLKENT----FLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEK- 1194
Query: 319 IHAAKLNVSLKSLEGER--NHIIIQLSEVDKTKEELTEHIKN-----LQTQQESLQSENI 371
+ ++ KSLE ++ + IQL K E L E N ++ ++ S
Sbjct: 1195 ---SNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRIS 1251
Query: 372 YFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLE 431
+ + K+++ L I T E E +L R+LT E+N + +AT QLE
Sbjct: 1252 HCQHRTTKVKEALLIKTCTVSELEAQL-RQLTEEQN----------TLNISFQQATHQLE 1300
Query: 432 TYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHN----- 486
K ++ ++E V +K+ + +K G + AA E ++ L+KE + N
Sbjct: 1301 EKENQIKSMKADIESLV--TEKEAL--QKEGGNQQQAASEKESCITQLKKELSENINAVT 1356
Query: 487 --KQKLTETELKFELLEKDPNALDV 509
K++L E +++ L K L+V
Sbjct: 1357 LMKEELKEKKVEISSLSKQLTDLNV 1381
Score = 59.3 bits (142), Expect = 1e-08
Identities = 97/451 (21%), Positives = 190/451 (42%), Gaps = 61/451 (13%)
Query: 59 LWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFE 118
LW V + Y +KL EKC+ ++ L KE + + + E
Sbjct: 626 LWTEKLQVLKQQYQTEMEKL--------REKCEQEKETLLKDKEIIFQAHIEEMNEKTLE 677
Query: 119 KAAAE--EARSLEATCEKLNRSNSELEDEILCL-----------EKDLKEEKSKHSQQ-D 164
K + E SL + ++ ++ +LE+E+ L E + E+K+ H QQ D
Sbjct: 678 KLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVD 737
Query: 165 ELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHK 224
++ + SIQ E K+LK QI + +++ K + ++ N + ++ S
Sbjct: 738 SIIKEHEVSIQRTE---KALKDQINQLELLLKERDKHLKEHQAHVE---NLEADIKRSEG 791
Query: 225 QLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLE 284
+L Q A++ +V + + Q T E +K + EQ+ ++ + T + + K A V
Sbjct: 792 ELQQASAKL---DVFQ-SYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV-- 845
Query: 285 EDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSE 344
E D EL+ + I L L+ E + L++
Sbjct: 846 EAQKKDVCTELDAHK-------------------IQVQDLMQQLEKQNSEMEQKVKSLTQ 886
Query: 345 VDKTKEELTEHIKNLQTQQESLQSENIYFES-ENQKLQQKLKIMTEFYQEDEMKLYRKLT 403
V ++K E + + QT+Q ++ EN+ + E QK ++++I+T+ E ++
Sbjct: 887 VYESKLE-DGNKEQEQTKQILVEKENMILQMREGQK--KEIEILTQKLSAKEDSIH---I 940
Query: 404 VEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGH 463
+ E Y + + + K+E+ +A E ET +K D E +L++ + ++ EK+ +
Sbjct: 941 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFN 1000
Query: 464 DNWL-AARTAERNLSDLRKENAHNKQKLTET 493
L A+ +SD N+++ E+
Sbjct: 1001 AKMLEMAQANSAGISDAVSRLETNQKEQIES 1031
Score = 54.7 bits (130), Expect = 3e-07
Identities = 85/385 (22%), Positives = 159/385 (41%), Gaps = 49/385 (12%)
Query: 98 LIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEK 157
L Q+ E E+ ++ A + + L CEK E+ EI L+++ ++
Sbjct: 1051 LNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEK-----EEMNKEITWLKEEGVKQD 1105
Query: 158 SKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENS 217
+ ++ E + S + SL + LK+ + E+ + + +L EN+
Sbjct: 1106 TTLNELQEQLKQKSAHVNSLAQDETKLKAHL--------------EKLEVDLNKSLKENT 1151
Query: 218 QLQTSHKQLFQQEAEVWKGEVSEL-NKQKITFED------SKVHAEQVLNDKENHIKTLT 270
LQ +L + AE K +VSEL +K K T E+ S + + L DK K L+
Sbjct: 1152 FLQEQLVEL-KMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1210
Query: 271 GHLPMMKD-----QAAVLEEDTTDDDNLELE----VNSQWENGANLDDPLKGALK-KLIH 320
L + D A+LE T + N+ + S+ + + +K AL K
Sbjct: 1211 EELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCT 1270
Query: 321 AAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKL 380
++L L+ L E+N + I + EE IK+++ ESL +E + E
Sbjct: 1271 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQ 1330
Query: 381 QQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDL 440
QQ +++ K + EN ++ ++E+L ++ + K DL
Sbjct: 1331 QQAAS------EKESCITQLKKELSENI-----NAVTLMKEELKEKKVEISSLSKQLTDL 1379
Query: 441 EEELERTVHFYQKQ-VISYEKRGHD 464
+L+ ++ +K+ IS ++ +D
Sbjct: 1380 NVQLQNSISLSEKEAAISSLRKQYD 1404
Score = 48.5 bits (114), Expect = 2e-05
Identities = 77/353 (21%), Positives = 151/353 (42%), Gaps = 60/353 (16%)
Query: 85 LIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELED 144
++E+K K L+ + QKE E+E + +EK A ++++ N E
Sbjct: 1851 ILEQKIKELDSCLVRQKEVHRVEMEELT--SKYEKLQA---------LQQMDGRNKPTE- 1898
Query: 145 EILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEER 204
LE++ +E+ H Q +L+++ +E + L+ ++A A+ E+
Sbjct: 1899 ---LLEENTEEKSKSHLVQPKLLSN-------MEAQHNDLEFKLAGAE---------REK 1939
Query: 205 RAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKEN 264
+ + K+ + L+ K+ QQE E+ K E + ++KI E + +
Sbjct: 1940 QKLG-KEIVRLQKDLRMLRKE-HQQELEILKKEYDQEREEKIKQEQEDLELK-------- 1989
Query: 265 HIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHA-AK 323
H TL + Q A E++ + ++ +N E A L + + +L+ A+
Sbjct: 1990 HNSTLKQLMREFNTQLAQKEQEL--EMTIKETINKAQEVEAELLESHQEETNQLLKKIAE 2047
Query: 324 LNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSE-NIYFESENQKLQQ 382
+ LK I+ D +EE+T +++LQTQ E LQ + E E
Sbjct: 2048 KDDDLKRTAKRYEEIL------DAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGND 2101
Query: 383 KLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRK 435
+ IM E + +L +K T+ + +++E+E E++ ++L+ Y K
Sbjct: 2102 NVTIM-----ELQTQLAQKTTLISDSKLKEQE----FREQIHNLEDRLKKYEK 2145
Score = 47.0 bits (110), Expect = 7e-05
Identities = 103/511 (20%), Positives = 203/511 (39%), Gaps = 76/511 (14%)
Query: 64 RSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAE 123
+ + S++ EQ T S L E KL E+ E E + +E L+ S E + +E
Sbjct: 1653 KQLLSQMEEKEEQYKKGTESHLSELNTKLQER------EREVHILEEKLK--SVESSQSE 1704
Query: 124 EARSLEATCEKLNRSNSELEDEILCLEKDLKEEKS----KHSQQDELMADISKSIQSLED 179
+ + E D C++K +E+ S +++++L+ + + +
Sbjct: 1705 TLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVS 1764
Query: 180 ESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVS 239
++ Q E I + + + I E + + + Q E G+ +
Sbjct: 1765 SHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNN 1824
Query: 240 ELNKQKI--TFED-SKVHAEQVLNDK--ENHIKTLTGHLPMMKDQAAV-LEEDTTDDDNL 293
KQ + F+D K E+ L + E IK L L K+ V +EE T+ + L
Sbjct: 1825 IQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKL 1884
Query: 294 ELEVNSQWENGAN--LDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEE 351
+ N L++ + K + KL L ++E + N + +L+ ++ K++
Sbjct: 1885 QALQQMDGRNKPTELLEENTEEKSKSHLVQPKL---LSNMEAQHNDLEFKLAGAEREKQK 1941
Query: 352 LTEHIKNLQTQQESLQSEN-----IYFESENQKLQQKLK----------------IMTEF 390
L + I LQ L+ E+ I + +Q+ ++K+K +M EF
Sbjct: 1942 LGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREF 2001
Query: 391 -----YQEDEMKLYRKLTVEENYRIEEE----------EKLSKVEEKLSRATEQLETYRK 435
+E E+++ K T+ + +E E + L K+ EK + Y +
Sbjct: 2002 NTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEE 2061
Query: 436 L-----------AKDLEEELERTVHFYQKQVISYEKRGHDN----WLAARTAERN--LSD 478
+ +DL+ +LE YQ+++ E G+DN L + A++ +SD
Sbjct: 2062 ILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISD 2121
Query: 479 LRKENAHNKQKLTETELKFELLEKDPNALDV 509
+ + ++++ E + + EK+ A V
Sbjct: 2122 SKLKEQEFREQIHNLEDRLKKYEKNVYATTV 2152
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 73.2 bits (178), Expect = 9e-13
Identities = 97/477 (20%), Positives = 203/477 (42%), Gaps = 39/477 (8%)
Query: 64 RSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEY-----EGYEVESSLEDASFE 118
+ VR+ ++++ + LS EE + + +Q+E E + ++ LE+ +
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Query: 119 KAA-AEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSL 177
A ++ SLEA + ++ S+ E + ++K L++ ++K Q+E + + + +IQ L
Sbjct: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
Query: 178 EDESKSLKSQI-----AEAKIICKTFKMSEERRAIAIKDALNENSQLQTSH--KQLFQQE 230
E L+ ++ +K + + EE R K QL+ + KQ +E
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
Query: 231 AEVWKGEVSELNKQ--KITFEDSK------VHAEQVLNDKENHIKTLTGHLPMMKDQAAV 282
+G+++ L+ Q + FE K + +L D + + L P ++ A +
Sbjct: 1629 KRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQL 1688
Query: 283 LEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHA-AKLNVSLKSLEGERNHIIIQ 341
+ + V ++ ++D L + + A L L L+ E+N I +
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIED-LHLQIDDIAKAKTALEEQLSRLQREKNEIQNR 1747
Query: 342 LSEVDKTKEELTEHIKNLQTQQ-------ESLQSENIYFESENQKLQQKLKIMTEFYQED 394
L E + EL + K Q LQ++ E Q+LQ+KL+ + +
Sbjct: 1748 LEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL-----QS 1802
Query: 395 EMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQ 454
+++ + V+++ +E K+ ++E +L Q++ LA L+E +E+ ++
Sbjct: 1803 QVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQR 1862
Query: 455 VISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSN 511
+ + + N + +R L D ++E +K E K LE D +L+ +N
Sbjct: 1863 IAAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAAN 1915
Score = 53.9 bits (128), Expect = 6e-07
Identities = 78/371 (21%), Positives = 146/371 (39%), Gaps = 41/371 (11%)
Query: 100 QKEYEGYEVESSLEDASFEKAAAEEAR---SLEATCEKLNRSNSELEDEILCLEKDLKEE 156
QK+ + EV+ E +K E+ L +++NR + E E L KDLK
Sbjct: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKR---LRKDLKRT 1661
Query: 157 KSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKD----- 211
K+ + +LM D K+ + E LK+Q+ E++ C + + + I+D
Sbjct: 1662 KALLADA-QLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQI 1720
Query: 212 --------ALNENSQLQTSHKQLFQQEAEVWKGEVSEL-NKQKITFEDSKVHAEQV---- 258
AL E K Q E + +++EL K K + Q+
Sbjct: 1721 DDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQ 1780
Query: 259 --LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL--------ELEVNSQWENGA--- 305
L + + L L ++ Q LE+ D + ELE ++E
Sbjct: 1781 AQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKR 1840
Query: 306 --NLDDPLKGALKKLIHAAKLNVSLKSLEGERN-HIIIQLSEVDKTKEELTEHIKNLQTQ 362
+L LK ++KL ++ ++ E E+N + QL + + EL +
Sbjct: 1841 LESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRK 1900
Query: 363 QESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEK 422
+ L+ + E+ NQ LQ LK+ + + + + ++ +EN + E S V+ +
Sbjct: 1901 KHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSE 1960
Query: 423 LSRATEQLETY 433
L + ++++
Sbjct: 1961 LEDRVDGVKSW 1971
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/205 (21%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 323 KLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQ-------SENIYFES 375
+L L+ E ERN + + ++ ELT + + + ES +E + E
Sbjct: 1265 QLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEK 1324
Query: 376 ENQKLQQK---LKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLET 432
E ++LQ + LK E + + M+ E N +++++ + K RA +++
Sbjct: 1325 EMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDF 1384
Query: 433 YRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
+K L++E E + Q+ E+R D + ++R L L+K+ +L +
Sbjct: 1385 TKKR---LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQD 1441
Query: 493 TELKFELLEKDPNALDVSNTAFGRE 517
T+L E + + L+ F E
Sbjct: 1442 TKLHLEGQQVRNHELEKKQRRFDSE 1466
Score = 32.3 bits (72), Expect = 1.7
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 20/133 (15%)
Query: 378 QKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLA 437
++LQQ+ + E Q+++ +L R+L + E + L ++++K R T +L+
Sbjct: 1387 KRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ------ 1440
Query: 438 KDLEEELERTVHFYQKQVISYE----KRGHDNWLAARTAERNLSDLRKENAHNKQKLTET 493
+ +H +QV ++E +R D+ L+ E L++E ++ +
Sbjct: 1441 -------DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
Query: 494 E---LKFELLEKD 503
E LK +L EKD
Sbjct: 1494 EAFSLKQQLEEKD 1506
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 73.2 bits (178), Expect = 9e-13
Identities = 97/477 (20%), Positives = 203/477 (42%), Gaps = 39/477 (8%)
Query: 64 RSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEY-----EGYEVESSLEDASFE 118
+ VR+ ++++ + LS EE + + +Q+E E + ++ LE+ +
Sbjct: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Query: 119 KAA-AEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSL 177
A ++ SLEA + ++ S+ E + ++K L++ ++K Q+E + + + +IQ L
Sbjct: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
Query: 178 EDESKSLKSQI-----AEAKIICKTFKMSEERRAIAIKDALNENSQLQTSH--KQLFQQE 230
E L+ ++ +K + + EE R K QL+ + KQ +E
Sbjct: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
Query: 231 AEVWKGEVSELNKQ--KITFEDSK------VHAEQVLNDKENHIKTLTGHLPMMKDQAAV 282
+G+++ L+ Q + FE K + +L D + + L P ++ A +
Sbjct: 1629 KRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQL 1688
Query: 283 LEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHA-AKLNVSLKSLEGERNHIIIQ 341
+ + V ++ ++D L + + A L L L+ E+N I +
Sbjct: 1689 KNQLEESEFTCAAAVKARKAMEVEIED-LHLQIDDIAKAKTALEEQLSRLQREKNEIQNR 1747
Query: 342 LSEVDKTKEELTEHIKNLQTQQ-------ESLQSENIYFESENQKLQQKLKIMTEFYQED 394
L E + EL + K Q LQ++ E Q+LQ+KL+ + +
Sbjct: 1748 LEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL-----QS 1802
Query: 395 EMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQ 454
+++ + V+++ +E K+ ++E +L Q++ LA L+E +E+ ++
Sbjct: 1803 QVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQR 1862
Query: 455 VISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSN 511
+ + + N + +R L D ++E +K E K LE D +L+ +N
Sbjct: 1863 IAAENREKEQN----KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAAN 1915
Score = 52.0 bits (123), Expect = 2e-06
Identities = 80/383 (20%), Positives = 149/383 (38%), Gaps = 43/383 (11%)
Query: 100 QKEYEGYEVESSLEDASFEKAAAEEAR---SLEATCEKLNRSNSELEDEILCLEKDLKEE 156
QK+ + EV+ E +K E+ L +++NR + E E L KDLK
Sbjct: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKR---LRKDLKRT 1661
Query: 157 KSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKD----- 211
K+ + +LM D K+ + E LK+Q+ E++ C + + + I+D
Sbjct: 1662 KALLADA-QLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQI 1720
Query: 212 --------ALNENSQLQTSHKQLFQQEAEVWKGEVSEL-NKQKITFEDSKVHAEQV---- 258
AL E K Q E + +++EL K K + Q+
Sbjct: 1721 DDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQ 1780
Query: 259 --LNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNL--------ELEVNSQWENGA--- 305
L + + L L ++ Q LE+ D + ELE ++E
Sbjct: 1781 AQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKR 1840
Query: 306 --NLDDPLKGALKKLIHAAKLNVSLKSLEGERN-HIIIQLSEVDKTKEELTEHIKNLQTQ 362
+L LK ++KL ++ ++ E E+N + QL + + EL +
Sbjct: 1841 LESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRK 1900
Query: 363 QESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEK 422
+ L+ + E+ NQ LQ LK+ + + + + ++ +EN + L + K
Sbjct: 1901 KHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDL--INSLQDMVTK 1958
Query: 423 LSRATEQLETYRKLAKDLEEELE 445
+ +LE + +LE+ ++
Sbjct: 1959 YQKRKNKLEGDSDVDSELEDRVD 1981
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/205 (21%), Positives = 87/205 (42%), Gaps = 13/205 (6%)
Query: 323 KLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQ-------SENIYFES 375
+L L+ E ERN + + ++ ELT + + + ES +E + E
Sbjct: 1265 QLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEK 1324
Query: 376 ENQKLQQK---LKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLET 432
E ++LQ + LK E + + M+ E N +++++ + K RA +++
Sbjct: 1325 EMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDF 1384
Query: 433 YRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTE 492
+K L++E E + Q+ E+R D + ++R L L+K+ +L +
Sbjct: 1385 TKKR---LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQD 1441
Query: 493 TELKFELLEKDPNALDVSNTAFGRE 517
T+L E + + L+ F E
Sbjct: 1442 TKLHLEGQQVRNHELEKKQRRFDSE 1466
Score = 32.3 bits (72), Expect = 1.7
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 20/133 (15%)
Query: 378 QKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLA 437
++LQQ+ + E Q+++ +L R+L + E + L ++++K R T +L+
Sbjct: 1387 KRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ------ 1440
Query: 438 KDLEEELERTVHFYQKQVISYE----KRGHDNWLAARTAERNLSDLRKENAHNKQKLTET 493
+ +H +QV ++E +R D+ L+ E L++E ++ +
Sbjct: 1441 -------DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
Query: 494 E---LKFELLEKD 503
E LK +L EKD
Sbjct: 1494 EAFSLKQQLEEKD 1506
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 72.4 bits (176), Expect = 2e-12
Identities = 99/471 (21%), Positives = 200/471 (42%), Gaps = 58/471 (12%)
Query: 86 IEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAA-EEARSLEATCEKLNRSNSELED 144
+E+K K + K L E + + E + EK EE +L+ C KL S + D
Sbjct: 311 LEDKIKDINK-KLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSD 369
Query: 145 EILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEER 204
+ E+ L + S E + + +++ E+E L S + + K+
Sbjct: 370 TMTEKERILAQSASV-----EEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRI 424
Query: 205 RAIAIKDAL--NENSQLQTSHKQLFQQEAEVWKGEV-------SELNKQKITFEDSKVHA 255
+ + +L E +LQ S +L E EV K SEL+ ++ E +
Sbjct: 425 EVLEKEKSLLSQEKEELQMSLLKL-NNEYEVIKSTATRDISLDSELHDLRLNLEAKEQEL 483
Query: 256 EQVLNDKENHIKTL----------TGHLPMMKDQAAVLE-EDTTDDDNLELEVNSQWENG 304
Q +++KE I + T H+ ++KDQ + + E + L+ ++N + +
Sbjct: 484 NQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRV 543
Query: 305 ANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHII---IQLSEVDKTKEELTEHIKNLQT 361
L+D K++++ K L+ ++ +I + L+++ TK++L + ++NL
Sbjct: 544 HQLEDD------------KMDIT-KELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVD 590
Query: 362 QQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRI------EEEEK 415
Q Q N+ + EN +L++ ++ E +L + L + N E E +
Sbjct: 591 QLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAE 650
Query: 416 LSKVEEKLSRATEQLETYRKLAKDLEEELERTV-------HFYQKQVISYEKRGHDNWLA 468
+ +++ LS + E +K+A D++ E E+ V H ++ + + +
Sbjct: 651 VRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTI 710
Query: 469 ARTAERNLSDLRKENAHNKQKLTETELKFE-LLEKDPNALDVSNTAFGREH 518
T + ++ E K++L E K+E +E+ NA +++ +A EH
Sbjct: 711 VETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEH 761
Score = 62.4 bits (150), Expect = 2e-09
Identities = 111/510 (21%), Positives = 212/510 (41%), Gaps = 88/510 (17%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE 133
+EQ+L ++S EK L+ + + ++ + L K E + +
Sbjct: 479 KEQELNQSIS----EKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQ 534
Query: 134 KLNRSNS---ELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSL-----K 185
LN +LED+ + + K+L +K K Q + + D+ + Q LED+ ++L K
Sbjct: 535 DLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNK 594
Query: 186 SQIAEAKIICKTFKMSEERRAIA---------IKDALNENSQLQTSHKQLFQQEAEV--W 234
SQ + I + ++ E R + +LN++S L ++EAEV
Sbjct: 595 SQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNL 654
Query: 235 KGEVSEL-----NKQKITFEDSKVHAEQVL--NDKENHIKT-LTGHLPMMKDQAAVLEED 286
K +SEL N +K+ F+ + + VL D + ++ L G+ + ++ ++E
Sbjct: 655 KQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVE-- 712
Query: 287 TTDDDNLELEVNSQWENGANLDDPLK--GALKKLIHAAKLNVSLKSLEGERNHII----- 339
T + E+E W L++ K +++L +A LN S LE E H+I
Sbjct: 713 TLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHE--HLIKLNQK 770
Query: 340 --IQLSEVDKTKEE---------------------LTEHIKNLQTQQESLQSENIYFESE 376
++++E+ K E+ LT+ I + E L+ + + E
Sbjct: 771 KDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEE 830
Query: 377 NQKLQQKLK---IMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRAT-----E 428
K Q L+ I+ + +E + L EEN ++EE L ++ E+ SR +
Sbjct: 831 LDKYSQALRKNEILRQTIEEKDRSL--GSMKEENNHLQEE--LERLREEQSRTAPVADPK 886
Query: 429 QLETYRKLAKD------LEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKE 482
L++ +LA + ++E LE + +QK + + + + ++ + + R +
Sbjct: 887 TLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQ 946
Query: 483 NAHNKQKLTETELKFELLEKDPNALDVSNT 512
H + T T+L LEKD + T
Sbjct: 947 --HEQMNATHTQL---FLEKDEEIKSLQKT 971
Score = 52.4 bits (124), Expect = 2e-06
Identities = 106/506 (20%), Positives = 201/506 (39%), Gaps = 92/506 (18%)
Query: 59 LWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFE 118
L V + L R +++ A + L E +L + + +++++E E++ + S+
Sbjct: 38 LMEGTEEVEAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYR 97
Query: 119 KAAAEEARSLEATCEKLNRSNSELEDEILCLEK----------------------DLKEE 156
++ E L L+D++L L+ +
Sbjct: 98 NQLQQK----EVEISHLKARQIALQDQLLKLQSAAQSVPSGAGVPATTASSSFAYGISHH 153
Query: 157 KSKHSQQDELMADISKS---IQSLEDESKSLKSQIAEAKIICKTFKM-----SEERRAIA 208
S D DI S I L +E L+S++ + I +T K S++
Sbjct: 154 PSAFHDDDMDFGDIISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICK 213
Query: 209 IKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKT 268
+++ + E Q ++ Q E V + ++QK+T E S+ H E+ L+D E I+
Sbjct: 214 LQNIIKELKQNRSQEIDDHQHEMSV----LQNAHQQKLT-EISRRHREE-LSDYEERIEE 267
Query: 269 LTGHLPMMKDQAAVLEEDTTDDDN-------LELEVNSQWENGANLDDPLKGALKKLIHA 321
L L + + V+E D + L++E + L+D +K KKL
Sbjct: 268 LENLL--QQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKL--- 322
Query: 322 AKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQ 381
S E +R+ + + +++ K ++ E +NL+ E KLQ
Sbjct: 323 -------SSAENDRDILRREQEQLNVEKRQIMEECENLKL--------------ECSKLQ 361
Query: 382 QKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKD-L 440
++ E E L + +VEE +R+ ++ LS E ++ R + L LA+D L
Sbjct: 362 PSAVKQSDTMTEKERILAQSASVEEVFRL--QQALSDAENEIMRLS-SLNQDNSLAEDNL 418
Query: 441 EEELERTVHFYQKQVISYEKR---------GHDNWLAARTAERNLS------DLRKENAH 485
+ ++ V +K ++S EK ++ + TA R++S DLR
Sbjct: 419 KLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEA 478
Query: 486 NKQKLTETELKFELLEKDPNALDVSN 511
+Q+L ++ + E L + LD N
Sbjct: 479 KEQELNQSISEKETLIAEIEELDRQN 504
Score = 51.2 bits (121), Expect = 4e-06
Identities = 74/351 (21%), Positives = 148/351 (42%), Gaps = 43/351 (12%)
Query: 133 EKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAK 192
E L ++ + L++ IL LE D+ + K ++ + E Q+L++ + + E +
Sbjct: 1438 ELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKE 1497
Query: 193 IICKTFKMSEERRAIAIKDALNENSQLQTSHKQ--------------LFQQEAEVWKGEV 238
C + K +A+A + L E Q +T +FQQE + +V
Sbjct: 1498 FECHSMK----EKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERD----QV 1549
Query: 239 SELNKQKITFEDSKVHAEQVLNDKE----NHIKTLTGHLPMMKD---QAAVLEEDTTDDD 291
KQK + + Q L DKE ++ L HL +D + A+ ED +
Sbjct: 1550 MLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDR--EA 1607
Query: 292 NLELEVNSQWENGANLDDPLKGALKKL-IHAAKLNVSLKSLEGERNHIIIQLSEVDKTKE 350
L +V E + + ++ A + + L L + +R+ +QLS + +
Sbjct: 1608 KLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVK 1667
Query: 351 ELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRI 410
+ + NLQ E Q E S +L+++ +++ E+ + E + ++++E
Sbjct: 1668 QYALSLANLQMVLEHFQQEEKAMYS--AELEKQKQLIAEWKKNAENLEGKVISLQECL-- 1723
Query: 411 EEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERTVHFYQKQVISYEKR 461
++ + + SR TEQL+ + ++ EEL+R Q+ + +K+
Sbjct: 1724 ---DEANAALDSASRLTEQLD----VKEEQIEELKRQNELRQEMLDDVQKK 1767
Score = 46.6 bits (109), Expect = 9e-05
Identities = 94/485 (19%), Positives = 201/485 (41%), Gaps = 76/485 (15%)
Query: 65 SVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEE 124
+ ++L++ +++++ + + + K +L E+ IQ + E+ ++ + E + +
Sbjct: 952 ATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKH 1011
Query: 125 ARSLEATCEKLNRSNSELEDEILCL-EKDLKEEKSKHSQQDELMADISKSIQSLEDESKS 183
S +A E+L + E E EI L EK++ K + + +++ IQ + E ++
Sbjct: 1012 DLS-KAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQA 1070
Query: 184 LKSQIAEAKII---------CKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQ----QE 230
L ++I+ + + M E+ + + ENS L+T + ++ +E
Sbjct: 1071 LHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKE 1130
Query: 231 AEVWKGEVSELNKQKIT---------FEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAA 281
A + K + + NK+ T F ++ + +++ +K+ I L+ + A
Sbjct: 1131 AALIK--LQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTL---LA 1185
Query: 282 VLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQ 341
VL+ +T ++ + N Q+E D LK +KK+ E + ++
Sbjct: 1186 VLQTSSTGNEAGGVNSN-QFEELLQERDKLKQQVKKM-------------EEWKQQVMTT 1231
Query: 342 LSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRK 401
+ + +L E + LQ Q + S+N N KLQ + + Y+++E KL K
Sbjct: 1232 VQNMQHESAQLQEELHQLQAQV-LVDSDN------NSKLQVDYTGLIQSYEQNETKL--K 1282
Query: 402 LTVEENYRIEEE------------EKLSKVEEKLSRATEQL-ETYRKLAKDLEEELERTV 448
+E +++ KL + +LS A+ ++ L E L +
Sbjct: 1283 NFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESS 1342
Query: 449 HFYQKQVISYEKRGHDNWLAARTAERN---LSDL--------RKENAHNKQKLTETELKF 497
Q+++ K + RT + N LSD RKE+ ++ + + K
Sbjct: 1343 ELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQ 1402
Query: 498 ELLEK 502
++L+K
Sbjct: 1403 DVLQK 1407
Score = 40.4 bits (93), Expect = 0.006
Identities = 88/432 (20%), Positives = 166/432 (38%), Gaps = 86/432 (19%)
Query: 86 IEEKCKLL----EKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSE 141
IEEK + L E+ + +Q+E E E S + + L + +LN
Sbjct: 848 IEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEH 907
Query: 142 LEDEI--------------LCLEKDLKEEKS-------KHSQQD----ELMADISKSIQS 176
LE+EI + L + L+E+K +H Q + +L + + I+S
Sbjct: 908 LEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKS 967
Query: 177 LEDESKSLKSQIAEAKIICKT-------------------------FKMSEERRAIAIKD 211
L+ + +K+Q+ E + +T K ER IK+
Sbjct: 968 LQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKE 1027
Query: 212 ALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTG 271
E L + L +Q ++ K EV +L Q I +D ++ A +H + +
Sbjct: 1028 RELEIKLLNEKNISLTKQIDQLSKDEVGKLT-QIIQQKDLEIQALHARISSTSHTQDVVY 1086
Query: 272 HLPMMKDQA-------AVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKL 324
++ A AVL E T ++ +L+ E + + I AAK
Sbjct: 1087 LQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMD----------------IVAAK- 1129
Query: 325 NVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKL 384
+L L+ E + + ++ E I+NL ++ ++I ++ +QK Q L
Sbjct: 1130 EAALIKLQDENKKLSTRFE--SSGQDMFRETIQNL---SRIIREKDIEIDALSQKCQTLL 1184
Query: 385 KIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEEL 444
++ +E EE ++E +KL + +K+ +Q+ T + + +L
Sbjct: 1185 AVLQTSSTGNEAGGVNSNQFEE--LLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQL 1242
Query: 445 ERTVHFYQKQVI 456
+ +H Q QV+
Sbjct: 1243 QEELHQLQAQVL 1254
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 72.4 bits (176), Expect = 2e-12
Identities = 102/439 (23%), Positives = 188/439 (42%), Gaps = 65/439 (14%)
Query: 100 QKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKSK 159
Q E E E++S+LE+A EE + L A E N+ +E+E ++ EKD + E++K
Sbjct: 1534 QLEVEKLELQSALEEAE-ASLEHEEGKILRAQLE-FNQIKAEIERKLA--EKDEEMEQAK 1589
Query: 160 HSQQ---DELMADISKSIQS----------LEDESKSLKSQI-------AEAKIICKTFK 199
+ Q D L + +S +E + ++ Q+ AEA+ K+ +
Sbjct: 1590 RNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1649
Query: 200 MSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVL 259
+ I + DA+ N L+ + + ++ + + E+ EL E S+ AEQ L
Sbjct: 1650 SLLKDTQIQLDDAVRANDDLK-ENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQEL 1708
Query: 260 NDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLI 319
+ ++ L + +Q +E D T L+ EV + N ++ K K +
Sbjct: 1709 IETSERVQLLHSQNTSLINQKKKMESDLT---QLQSEVEEAVQECRNAEEKAK---KAIT 1762
Query: 320 HAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIYFESENQK 379
AA + LK + H+ ++ K+ + + IK+LQ + + ++E I + ++
Sbjct: 1763 DAAMMAEELKKEQDTSAHL-------ERMKKNMEQTIKDLQHRLD--EAEQIALKGGKKQ 1813
Query: 380 LQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRK---L 436
L QKL+ +L +L E+ E + + K E ++ T Q E +K
Sbjct: 1814 L-QKLEARVR-------ELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLR 1865
Query: 437 AKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELK 496
+DL ++L+ V Y++Q E++ A NLS RK + +L E E +
Sbjct: 1866 LQDLVDKLQLKVKAYKRQAEEAEEQ----------ANTNLSKFRKV----QHELDEAEER 1911
Query: 497 FELLEKDPNALDVSNTAFG 515
++ E N L + G
Sbjct: 1912 ADIAESQVNKLRAKSRDIG 1930
Score = 70.5 bits (171), Expect = 6e-12
Identities = 104/497 (20%), Positives = 208/497 (41%), Gaps = 49/497 (9%)
Query: 43 LVVCAAVIGFFVVLLFLW-RSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQK 101
LV+ + F V + W + + ++ L +K AT+ + LEK +K
Sbjct: 814 LVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAETEKEMATMKEEFGRIKETLEKSEARRK 873
Query: 102 EYEGYEVESSLEDASFE---KAAAEEARSLEATCEKLNRSNSELEDEILCLEKDLKEEKS 158
E E V E + +A + E C++L ++ +LE ++ KE
Sbjct: 874 ELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKV-------KEMNE 926
Query: 159 KHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC------------KTFKMSEERRA 206
+ ++E+ A+++ + LEDE LK I + ++ K ++EE
Sbjct: 927 RLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 986
Query: 207 I--AIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFED-------SKVHAEQ 257
+ I E LQ +H+Q + +V + +V+ L+K K+ E S ++
Sbjct: 987 LDEIIAKLTKEKKALQEAHQQAL-DDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKK 1045
Query: 258 VLNDKENHIKTLTGHLPMMKDQAAVLEEDTTD-DDNL---ELEVNSQWENGANLDDPLKG 313
V D E + L G L + ++ LE D ++ L E ++N Q + ++D
Sbjct: 1046 VRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQ---NSKIEDEQVL 1102
Query: 314 ALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQE------SLQ 367
AL+ + ++ LE E ++V+K + +L+ ++ + + E S+Q
Sbjct: 1103 ALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQ 1162
Query: 368 SE-NIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRA 426
E N E+E QK+++ L+ T ++ L +K E+ + L +V++KL +
Sbjct: 1163 IEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKE 1222
Query: 427 TEQLETYRKLAKDLEEELERTVHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHN 486
+ + E++ + +K + E + ++ + A+R+L+D + A
Sbjct: 1223 KSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRA-- 1280
Query: 487 KQKLTETELKFELLEKD 503
K + EL +L EK+
Sbjct: 1281 KLQTENGELARQLEEKE 1297
Score = 63.2 bits (152), Expect = 9e-10
Identities = 101/515 (19%), Positives = 202/515 (39%), Gaps = 103/515 (20%)
Query: 74 REQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCE 133
R ++ G S IE K +F ++++ E ++ A+ K A+ L +
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 134 KLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKI 193
L R +LE E + +L + S Q + A++ K ++LED++ + ++ EA+
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 194 ICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKV 253
++ D + ++LQT + +L +Q E + +S+L + K+++
Sbjct: 1271 --------------SLNDFTTQRAKLQTENGELARQLEEK-EALISQLTRGKLSYTQQME 1315
Query: 254 HAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVN----------SQWEN 303
++ L ++ L L + +L E ++ + E+ +QW
Sbjct: 1316 DLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT 1375
Query: 304 GANLD-----DPLKGALKKLIHAAK--------LNVSLKSLEGERNHIIIQLSEV----- 345
D + L+ A KKL + +N SLE ++ + ++ ++
Sbjct: 1376 KYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVE 1435
Query: 346 ----------------DKTKEELTEHIKNLQTQQESLQSE------------NIYFES-- 375
DK E + + Q++ ES Q E N Y ES
Sbjct: 1436 RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE 1495
Query: 376 -------ENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEE------- 421
EN+ LQ+++ +TE E ++ V + +E+ E S +EE
Sbjct: 1496 HLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEH 1555
Query: 422 ---KLSRATEQL-----ETYRKLAKDLEEELERTVHFYQKQV------ISYEKRGHDNWL 467
K+ RA + E RKLA + +EE+E+ +Q+ V + E R + L
Sbjct: 1556 EEGKILRAQLEFNQIKAEIERKLA-EKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVL 1614
Query: 468 -AARTAERNLSDLRKENAHNKQKLTETELKFELLE 501
+ E +L+++ + +H + E + + + L+
Sbjct: 1615 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQ 1649
Score = 52.0 bits (123), Expect = 2e-06
Identities = 65/374 (17%), Positives = 159/374 (42%), Gaps = 58/374 (15%)
Query: 76 QKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEATCEKL 135
Q++ +L ++ + + + ++K+ EG + +E
Sbjct: 1593 QRVVDSLQTSLDAETRSRNEVLRVKKKMEG------------------DLNEMEIQLSHA 1634
Query: 136 NRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIIC 195
NR +E + ++ L+ LK+ + + D+ ++I +E + L++++ E + +
Sbjct: 1635 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAV- 1693
Query: 196 KTFKMSEERRAIAIKDALNENSQLQTSHKQ---LFQQEAEVWKGEVSELNKQKITFEDSK 252
+ +E R +A ++ + + ++Q H Q L Q+ K S+L + + E++
Sbjct: 1694 --VEQTERSRKLAEQELIETSERVQLLHSQNTSLINQK----KKMESDLTQLQSEVEEA- 1746
Query: 253 VHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLK 312
++ N +E K +T AA++ E+ + + + + N++ +K
Sbjct: 1747 --VQECRNAEEKAKKAIT--------DAAMMAEELKKEQDTSAHLERMKK---NMEQTIK 1793
Query: 313 GALKKLIHAAKLNVSLKSLEGERNHIIIQLSEVDKTKEELTEHIKNLQTQQESLQSENIY 372
+L A ++ +L+G + K ++L ++ L+ + E+ Q N
Sbjct: 1794 DLQHRLDEAEQI-----ALKGGK-----------KQLQKLEARVRELEGELEAEQKRNAE 1837
Query: 373 FESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLET 432
+K ++++K +T +ED+ L R + + +++ + + EE +A L
Sbjct: 1838 SVKGMRKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSK 1897
Query: 433 YRKLAKDLEEELER 446
+RK+ +L+E ER
Sbjct: 1898 FRKVQHELDEAEER 1911
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,421,720
Number of Sequences: 37866
Number of extensions: 2181842
Number of successful extensions: 19857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 307
Number of HSP's successfully gapped in prelim test: 1367
Number of HSP's that attempted gapping in prelim test: 10410
Number of HSP's gapped (non-prelim): 6088
length of query: 777
length of database: 18,247,518
effective HSP length: 110
effective length of query: 667
effective length of database: 14,082,258
effective search space: 9392866086
effective search space used: 9392866086
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.