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Search of human proteins with 146134388
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|146134388 YLP motif containing 1 [Homo sapiens]
(2146 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|146134388 YLP motif containing 1 [Homo sapiens] 4510 0.0
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 141 6e-33
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 127 2e-28
gi|110349719 titin isoform N2-A [Homo sapiens] 115 4e-25
gi|160707881 formin 2 [Homo sapiens] 110 1e-23
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 109 3e-23
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 108 6e-23
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 107 1e-22
gi|47132519 Ras association and pleckstrin homology domains 1 is... 104 8e-22
gi|7706501 WW domain binding protein 11 [Homo sapiens] 104 8e-22
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 103 2e-21
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 103 2e-21
gi|116284392 mucin 2 precursor [Homo sapiens] 100 1e-20
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 97 1e-19
gi|55750053 atrophin-1 [Homo sapiens] 97 2e-19
gi|55750041 atrophin-1 [Homo sapiens] 97 2e-19
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 97 2e-19
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 96 5e-19
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 96 5e-19
gi|150170670 piccolo isoform 2 [Homo sapiens] 96 5e-19
gi|150378539 piccolo isoform 1 [Homo sapiens] 96 5e-19
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 95 6e-19
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 94 1e-18
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 94 1e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni... 94 2e-18
gi|11386183 WAS protein family, member 2 [Homo sapiens] 92 5e-18
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 92 5e-18
gi|150417989 cyclin K isoform 1 [Homo sapiens] 92 7e-18
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 91 9e-18
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 91 2e-17
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 4510 bits (11697), Expect = 0.0
Identities = 2146/2146 (100%), Positives = 2146/2146 (100%)
Query: 1 MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQ 60
MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQ
Sbjct: 1 MYPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQ 60
Query: 61 LQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ 120
LQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ
Sbjct: 61 LQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ 120
Query: 121 QQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS 180
QQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS
Sbjct: 121 QQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS 180
Query: 181 QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS 240
QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS
Sbjct: 181 QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS 240
Query: 241 KSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQ 300
KSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQ
Sbjct: 241 KSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQ 300
Query: 301 HLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV 360
HLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV
Sbjct: 301 HLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV 360
Query: 361 PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQ 420
PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQ
Sbjct: 361 PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQ 420
Query: 421 QIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEK 480
QIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEK
Sbjct: 421 QIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEK 480
Query: 481 QWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPP 540
QWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPP
Sbjct: 481 QWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPP 540
Query: 541 SLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAG 600
SLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAG
Sbjct: 541 SLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAG 600
Query: 601 PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSS 660
PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSS
Sbjct: 601 PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSS 660
Query: 661 QVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL 720
QVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL
Sbjct: 661 QVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL 720
Query: 721 GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP 780
GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP
Sbjct: 721 GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP 780
Query: 781 KGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGP 840
KGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGP
Sbjct: 781 KGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGP 840
Query: 841 KPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNE 900
KPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNE
Sbjct: 841 KPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNE 900
Query: 901 NLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPS 960
NLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPS
Sbjct: 901 NLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPS 960
Query: 961 KTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSY 1020
KTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSY
Sbjct: 961 KTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEGNRGNSSSY 1020
Query: 1021 RGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRD 1080
RGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRD
Sbjct: 1021 RGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRD 1080
Query: 1081 RGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAG 1140
RGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAG
Sbjct: 1081 RGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAG 1140
Query: 1141 SRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERG 1200
SRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERG
Sbjct: 1141 SRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERG 1200
Query: 1201 HEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDR 1260
HEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDR
Sbjct: 1201 HEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDR 1260
Query: 1261 RGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQE 1320
RGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQE
Sbjct: 1261 RGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQE 1320
Query: 1321 SQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERG 1380
SQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERG
Sbjct: 1321 SQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERG 1380
Query: 1381 DTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQ 1440
DTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQ
Sbjct: 1381 DTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASLDSDQ 1440
Query: 1441 GLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTS 1500
GLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTS
Sbjct: 1441 GLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTS 1500
Query: 1501 SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPP 1560
SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPP
Sbjct: 1501 SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPP 1560
Query: 1561 VIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP 1620
VIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP
Sbjct: 1561 VIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP 1620
Query: 1621 GPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHA 1680
GPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHA
Sbjct: 1621 GPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHA 1680
Query: 1681 GQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740
GQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPR
Sbjct: 1681 GQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740
Query: 1741 DDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSL 1800
DDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSL
Sbjct: 1741 DDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSL 1800
Query: 1801 SHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVE 1860
SHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVE
Sbjct: 1801 SHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVE 1860
Query: 1861 FGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKT 1920
FGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKT
Sbjct: 1861 FGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKT 1920
Query: 1921 LDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEI 1980
LDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEI
Sbjct: 1921 LDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEI 1980
Query: 1981 NKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEESELGYI 2040
NKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEESELGYI
Sbjct: 1981 NKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEESELGYI 2040
Query: 2041 PKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYDTRASEPGKKRVR 2100
PKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYDTRASEPGKKRVR
Sbjct: 2041 PKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYDTRASEPGKKRVR 2100
Query: 2101 WADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAEKALNRTKYI 2146
WADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAEKALNRTKYI
Sbjct: 2101 WADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAEKALNRTKYI 2146
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 141 bits (356), Expect = 6e-33
Identities = 254/1062 (23%), Positives = 381/1062 (35%), Gaps = 208/1062 (19%)
Query: 15 PPPPVPP--PPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
PPP P PPP P SP P S + P E + L + + +
Sbjct: 442 PPPEESPLSPPPEESP-TSPPPEASRLSPPP----------EELPASPLPEALHLSRPLE 490
Query: 73 QCVLQPHHLPPP--PLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHH 130
+ L P PP PL PPP + P PP PP PAL + L
Sbjct: 491 ESPLSP---PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSP 547
Query: 131 QRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYM-PPPQPPPSYYPPTSSQPYLPPAQP 189
+ P L P E P PP PP +S M PPP+ P PP +S+ + PP +
Sbjct: 548 PFEESP-LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF-PPFEE 605
Query: 190 SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQL----- 244
SP PP +S L+P P S S + S P ++ S P + S L
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPED----SPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
Query: 245 LAPPPPSAP--PGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHL 302
L+PPP +P P + + P E+ + E +P P+ S +P + L
Sbjct: 662 LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDS------L 715
Query: 303 LSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPE-SPSSEEPPLPPPNEEVP 361
+SL ++ P++ P+ EE + S+ P SP EEP L P EE
Sbjct: 716 MSLPL---------EESPLL------PLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-- 758
Query: 362 PPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQ 421
P PQ+E+P + ++ A + H + + + + +L Q +
Sbjct: 759 ---PHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA--EGPHLSPQPEELHLSPQTEEP 813
Query: 422 IIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQ 481
+ P P +S + H Q + E E+ H P +L++
Sbjct: 814 HLSPVPEEPCLSPQPEESHLSPQSE---------EPCLSPRPEESHLSP---ELEKPPLS 861
Query: 482 WKTWQGHMKATQSYLQEKVNSF----QNMKNQYMGNMSMPPPFVP-YSQMPPPLPTMPPP 536
+ + + Q E++ F + + +G ++ P P S +P LP P
Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG 921
Query: 537 VLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPP---------SLSSAGP 587
PSL P +M PP +PPP+ P + T+ PP + P + + P
Sbjct: 922 --EPSLSPQLM--------PPDPLPPPLSP--IITAAAPPALSPLGELEYPFGAKGDSDP 969
Query: 588 PPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP-PGVPQGIPPQL 646
L P L + P+ PPP + T P PV PP +PP PG P G +
Sbjct: 970 ESPLAAPILET----PISPPPEANCTDPEPV----------PPMILPPSPGSPVGPASPI 1015
Query: 647 TAAPVPPASSS--QSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPL 704
P+PP S Q S VP+ P+ P A P + PL G V+ +A L
Sbjct: 1016 LMEPLPPQCSPLLQHSLVPQNSPPSQCSPP-----ALPLSVPSPLSPIGKVVGVSDEAEL 1070
Query: 705 SKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDG 764
+ E + P P +P +S L SP G
Sbjct: 1071 HEMET------------EKVSEPECPAL--------------EPSATSPLPSPMG----- 1099
Query: 765 PRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITP 824
DL P P F G D +G A G++ + G P AS+ +P
Sbjct: 1100 -----DLSCPAPSPAPALDDFSGLGED--TAPLDGIDAPGSQPEPGQTPGSLASELKGSP 1152
Query: 825 STSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAF 884
L P + P P +Q Q P +EP A + K
Sbjct: 1153 -VLLDPEELAP----VTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIK------ 1201
Query: 885 SIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQP 944
D+ SN + D+ P SE G +P + +++
Sbjct: 1202 ------SDIVNEISNLSQGDASASFPGSEPLLGSPDP--------------EGGGSLSME 1241
Query: 945 VPLANKPVPAQSTFPSKTGGMEGGTAVATSSL--TADNDFKPVGIGLPHSENNQDKGLPR 1002
+ ++ PA+ EG + T SL T D+ G + + +KG R
Sbjct: 1242 LGVSTDVSPARD---------EGSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRR 1292
Query: 1003 PDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQA 1044
+R++ +G SSS+ PG+ R G RGRG+A
Sbjct: 1293 SSPARSRIK--QGRSSSF--PGRRRPRGGAHGG---RGRGRA 1327
Score = 75.5 bits (184), Expect = 5e-13
Identities = 154/671 (22%), Positives = 220/671 (32%), Gaps = 116/671 (17%)
Query: 16 PPPVPPPPP--VALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQ 73
P P PPPP ALP S P S PA+P S Q +Q + +
Sbjct: 2385 PRPQPPPPESCCALPPRSL-PSDPFSRVPASPQS--------QSSSQSPLTPRPLSAEAF 2435
Query: 74 CV--LQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQ 131
C + P P P PP P PP P PP A K H L
Sbjct: 2436 CPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAF---KAGSLAHTSLG-- 2490
Query: 132 RDGPPGLVPM----ELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPA 187
G P +P EL + S P P + +++ P P +P +P L P
Sbjct: 2491 AGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP 2550
Query: 188 QPSPSQSPPS--QSYLAPTPSYSSSSSSSQSYLSHSQSYLPS-SQASPSRPSQGHSKS-Q 243
P P PP S+ P P+ S++ Y + ++ PS S PS S G S
Sbjct: 2551 VPQPGLPPPHGINSHFGPGPTLGKPQSTN--YTVATGNFHPSGSPLGPSSGSTGESYGLS 2608
Query: 244 LLAPP---PPSAPPGNKTTV----------------QQEPLESGAKNKSTEQQQAAPEPD 284
L PP PP AP G+ + +++P + +T + +P
Sbjct: 2609 PLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPG 2668
Query: 285 PSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPE 344
S ++ E ++ RQ L L R ++ ++T KE A + P
Sbjct: 2669 MSGLSQTELEKQRQRQRLRELLIRQQIQ-----------RNTLRQEKETAAAAAGAVGPP 2717
Query: 345 SPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQG 404
EP P + P Q + +L G
Sbjct: 2718 GSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILG-------------PG 2764
Query: 405 IMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEE 464
+L + PPP S+D+ R Q F
Sbjct: 2765 SFPSDDRLSR----------PPPPATPSSMDVNSRQLVGGSQAFY--------------- 2799
Query: 465 QLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNS-FQNMKNQYMGNMSMPPPFVPY 523
Q YP LQ+ ++Q WQ + ++ +++ F + +G ++ P
Sbjct: 2800 QRAPYPGSLPLQQQQQQ--LWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGI 2857
Query: 524 S-QMPPPLPTMPPPVLPPS---LPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMP 579
S ++P P +P P P L V P P PG PP P P S P +
Sbjct: 2858 STRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLA 2917
Query: 580 P----SLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
P L+ +G PP P SA P P L +S P P P L + PP
Sbjct: 2918 PEGLRGLAVSGLPPQKP-----SAPPAPELN----NSLHPTPHTKGPTLPTGLELVNRPP 2968
Query: 636 PGVPQGIPPQL 646
G P L
Sbjct: 2969 SSTELGRPNPL 2979
Score = 72.4 bits (176), Expect = 4e-12
Identities = 94/362 (25%), Positives = 130/362 (35%), Gaps = 69/362 (19%)
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMP--PPVMPPSLPT 571
+ +PP Q+P +P+ P L P+ P P P T PP P P PP L
Sbjct: 2161 LKLPP------QVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGA 2214
Query: 572 S------------VPPPGMPPSLSSAGPPPVLPP--PSLSSAGPP------------PVL 605
S PPG P S P P L P PSL + P P+L
Sbjct: 2215 SSRPGAGQPGEFHTTPPGTPRHQPST-PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLL 2273
Query: 606 PPPSLSSTAPPPVMPLPPLSSATP---PPGI-----PPPGVPQG----IPPQLTAAPVPP 653
PP + + L +++P PP + P G G P + AP+ P
Sbjct: 2274 SPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTP 2333
Query: 654 ASSSQSSQV------PEKPRP--ALLPTPVSFGSA-PPTTYHPPLQSAGPSEQVNSKAPL 704
+S Q P++P P AL P+P S P +Y P + + P
Sbjct: 2334 RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPE 2393
Query: 705 SKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDP-PRSSYLESPRGPRFD 763
S ALP S SD S P+ P + L P P ++ SP PRF
Sbjct: 2394 SCCALPPRSLPSD----PFSRVPASP----QSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ 2445
Query: 764 GPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYE----GHPAEGTKSKWGMIPRGPASQ 819
P + SR + P P + RP P ++ H + G +P GPA +
Sbjct: 2446 SPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGE 2505
Query: 820 FY 821
+
Sbjct: 2506 LH 2507
Score = 65.5 bits (158), Expect = 5e-10
Identities = 174/730 (23%), Positives = 241/730 (33%), Gaps = 144/730 (19%)
Query: 536 PVLPPSLPPPVMPPALPATVPPPGMPP------PVMPPSLPTSV-----PPPGMPPSLSS 584
P L +PP P AL + PPP P P P L TS PP G P S
Sbjct: 2100 PALHLRIPP--QPGALGS--PPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDS 2155
Query: 585 AGP-----PPVLPP--PSLSSAGPPPVLPPPSLSSTAPPPVMPL---------PPLSSAT 628
G PP +P PS G P P TAPP P PP+ A+
Sbjct: 2156 PGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGAS 2215
Query: 629 PPPGIPPPG----VPQGIPPQLTAAP----VPPASSSQSSQVPEKP--------RPALLP 672
PG PG P G P + P P S + VPE P P L P
Sbjct: 2216 SRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSP 2275
Query: 673 TPV------------SFGSAPPTTYHPP----LQSAGPSEQVNS---------KAPLSKS 707
P G++ P +Y PP + S + KAPL+
Sbjct: 2276 PPFGESRKALEVKKEELGASSP-SYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPR 2334
Query: 708 ALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRR 767
A S GL P+Q L P PP S+ + R + P
Sbjct: 2335 ASQVEPQSPGLGLRPQEPPPAQ-------------ALAPSPP--SHPDIFRPGSYTDPYA 2379
Query: 768 FEDLGSRCEGPRPKG-----PRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYI 822
L R + P P+ PR + P P R P + S+ + PR P S
Sbjct: 2380 QPPLTPRPQPPPPESCCALPPR---SLPSDPFSRVPASPQSQSSSQSPLTPR-PLS---- 2431
Query: 823 TPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSA 882
+ + P P+++ P P + Q + PL +K P K +
Sbjct: 2432 --AEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPL--HKPPRPQPPEVAFKAGSLAHT 2487
Query: 883 AFSIAADVKDVKAAQSNE-NLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAV 941
+ + A + E + +PP S G ++ Q ++
Sbjct: 2488 SLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSL 2547
Query: 942 TQPVPLANKPVP--AQSTFPSKTGGMEGGTAVATSSLTADNDFKPVG--IGLPHSENNQD 997
PVP P P S F G G +T+ A +F P G +G +
Sbjct: 2548 KPPVPQPGLPPPHGINSHFGP---GPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGES 2604
Query: 998 KGL-----------PRPDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAIS 1046
GL P PD L + +S R S +E D G G A +
Sbjct: 2605 YGLSPLRPPSVLPPPAPDGSLPYL----SHGASQRSGITSPVEKREDPG-TGMGSSLATA 2659
Query: 1047 RGPGLVKQEDFRDKMMGRREDSREKMNRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAA 1106
PG M G + EK + + R+ L+R R L+ ++ AA
Sbjct: 2660 ELPGTQD-----PGMSGLSQTELEKQRQRQRLREL-LIRQQIQRNT----LRQEKETAAA 2709
Query: 1107 GSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPPRG-PGSRERG--LGRSDFG 1163
+ GPP G++ P SR + P AG++++ G P S+ G LG F
Sbjct: 2710 AAGAVGPPGSWGAEPSSPAFEQLSRGQTP--FAGTQDKSSLVGLPPSKLSGPILGPGSFP 2767
Query: 1164 RDRGPFRPEP 1173
D RP P
Sbjct: 2768 SDDRLSRPPP 2777
Score = 63.5 bits (153), Expect = 2e-09
Identities = 170/811 (20%), Positives = 262/811 (32%), Gaps = 137/811 (16%)
Query: 117 YQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYP 176
Y+ +QQ + Q Q+ ++ + P PG +P + PPQ PP
Sbjct: 3595 YRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHG--LQPPQGPPG--G 3650
Query: 177 PTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPS 236
P P Q P + +++ + Q HS
Sbjct: 3651 QAGGLRLTPGGMALPGQ---------PGGPFLNTALAQQQQQQHS--------------- 3686
Query: 237 QGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQY 296
G + S LA P PGN P + + + QQ + Q+QQQ
Sbjct: 3687 -GGAGS--LAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQ 3743
Query: 297 WYRQHLL---SLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQV--------PES 345
+QHLL ++QQ+ ++GP V + K + +P +S P+
Sbjct: 3744 --QQHLLGQVAIQQQ-------QQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP 3794
Query: 346 PSSEEPPLPPPNEEV-----PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQ--------- 391
P + L P V P L P+ P + +R+ A Q
Sbjct: 3795 PQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVT 3854
Query: 392 -QHQQHRVGFQYQGIM---------------------------------QKHTQLQQILQ 417
Q QQ + Q QG M Q+ Q QQ+ Q
Sbjct: 3855 AQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQ 3914
Query: 418 QYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQE 477
Q QQ +Q +Q + Q + ++QQQQ Q L Q+ ++ Q ++Q + + Q Q+
Sbjct: 3915 QQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQ 3974
Query: 478 YE--KQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMP-PPLPTMP 534
Q +T + + Q Q++V M + + + S P P + T+
Sbjct: 3975 MGLLNQSRT----LLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVD 4030
Query: 535 PPVLPPSLPPPVM----PPALPATVPPPGMPPPVMPPSLPTS------VPPPGMPPSLSS 584
P V + P P A+ T P + PSL P P PS
Sbjct: 4031 PAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090
Query: 585 AGPPPVLPPPS--------LSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPG---- 632
PP LP + G L S S + P + P S PG
Sbjct: 4091 LQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQ 4150
Query: 633 --IPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGS--APPTTYHPP 688
+ P P Q P PP P ++PT + +P
Sbjct: 4151 NLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQ 4210
Query: 689 LQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDP 748
L+ P +Q +A L + L S + + P+ + + GG P P
Sbjct: 4211 LRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGG-FPGP 4269
Query: 749 PRSSYLESPRGPRFDGPRRF-EDLGSRCEGP--RPKGPRFEGNRPDGP-RPRYEGHPAEG 804
E GPR GP R G+ GP P P + P P RP P+
Sbjct: 4270 QTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQ 4329
Query: 805 TKSKWGMIPRGPASQFYITPSTSLSPRQSGP 835
++ + P P + P+ P + P
Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSP 4360
Score = 59.3 bits (142), Expect = 4e-08
Identities = 158/684 (23%), Positives = 224/684 (32%), Gaps = 146/684 (21%)
Query: 43 AAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQP 102
A P S ++Q L Q QQLQQ Q+Q+Q Q L L Q
Sbjct: 3891 AQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQ---QQQQLQQQQLQQQQQQQ-----QLQQ 3942
Query: 103 PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPME--LESPPESP----PVPPGS 156
L Q+QQQ + Q Q+ GL+ L SP + + PG
Sbjct: 3943 QQQQQLQQQQQQLQ-QQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM 4001
Query: 157 YMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQS 216
P Q + P P+ Q + PA S + PS P ++ S
Sbjct: 4002 PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESM--- 4058
Query: 217 YLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQ 276
+++ +PS LL P P P +++Q +P
Sbjct: 4059 ----------ATEPGEVKPSLSGDSQLLLVQPQPQPQP---SSLQLQP------------ 4093
Query: 277 QQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTV 336
P + Q+QQQ + +H G + + E +V
Sbjct: 4094 --------PLRLPGQQQQQV------------SLLHTAGGGSHGQLGSGSS---SEASSV 4130
Query: 337 PATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQH 396
P P ++P N L P++P E P ++ Q Q Q
Sbjct: 4131 PHLLAQPSVSLGDQPGSMTQN-----LLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQ-- 4183
Query: 397 RVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWE 456
G GIM QL+ LQ ++ + QLRH QQQQ
Sbjct: 4184 --GLPGVGIMPTVGQLRAQLQ------------GVLAKNPQLRHLSPQQQQ--------- 4220
Query: 457 REFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSM 516
QL + + QLQ+ + +T TQ+ + + Q + G +
Sbjct: 4221 --------QLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTG 4272
Query: 517 PPPFV---PYSQMPPPLPTMP-----PPVLPP--SLPPPVMP--PALPATVPPPGMPPPV 564
P + P Q PP LP P PVL P PPP P P P+ +P P P
Sbjct: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPT 4332
Query: 565 ---MPPSLPTSVPP--PGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVM 619
+PP+ P + P P + P P +L S G P PP +L+ T P
Sbjct: 4333 EAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQS 4392
Query: 620 PLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGS 679
L P G Q+ VP AS Q P + AL V +
Sbjct: 4393 SLVP-----------------GHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREA 4435
Query: 680 ------APPTTYHPPLQSAGPSEQ 697
AP T+ H L AGP +
Sbjct: 4436 NGEPIGAPGTSNH--LLLAGPRSE 4457
Score = 57.4 bits (137), Expect = 1e-07
Identities = 53/187 (28%), Positives = 72/187 (38%), Gaps = 21/187 (11%)
Query: 1462 ELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP 1521
E K L + QL+ + +M PP+ES L PPP + R PP +
Sbjct: 415 EAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEEL 474
Query: 1522 PGSIVRPSAPPARSSVPVTRP--PVPIPPPPPPPPLPPPP------PVIKPQTSAVEQER 1573
P S P ++ ++RP P+ PPP PL PPP P+ + S E+
Sbjct: 475 PAS-------PLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP 527
Query: 1574 WDEDSFYGLWDTNDEQGLNSEFKSETAAIP--SAPVLPPPPVHSSIPPPGPVPMGMP--- 1628
L + L+ F+ + P P PPP PPP PM P
Sbjct: 528 PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
Query: 1629 -PMSKPP 1634
PMS PP
Sbjct: 588 SPMSPPP 594
Score = 55.8 bits (133), Expect = 4e-07
Identities = 68/261 (26%), Positives = 95/261 (36%), Gaps = 25/261 (9%)
Query: 510 YMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSL 569
++G + + P V + + P + P L P PPA PP P P S
Sbjct: 2315 HLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY 2374
Query: 570 PTSVPPPGMPPSLSSAGPPP-----VLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPL 624
P PP PPP LPP SL S V P S++ P+ P P
Sbjct: 2375 ---TDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLS 2431
Query: 625 SSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF--GSAPP 682
+ A P + P P + P P S + + + PRP P V+F GS
Sbjct: 2432 AEAFCPSPVTPRFQS---PDPYSRPPSRPQSRDPFAPLHKPPRPQ--PPEVAFKAGSLAH 2486
Query: 683 TTY----HPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMP 738
T+ P AGP+ ++++K P + +F G G PS P+
Sbjct: 2487 TSLGAGGFPAALPAGPAGELHAKVPSGQP----PNFVRSPGTGAFVGTPS-PMRFTFPQA 2541
Query: 739 VRSGGLLPDPPRSSYLESPRG 759
V L P P+ L P G
Sbjct: 2542 VGEPSLKPPVPQPG-LPPPHG 2561
Score = 55.1 bits (131), Expect = 7e-07
Identities = 45/157 (28%), Positives = 60/157 (38%), Gaps = 9/157 (5%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP 1549
PP+ES L P S PP P ++ P +PP +S P++ P P
Sbjct: 497 PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEAS-PLSPPFEESPLS 555
Query: 1550 PPPPPLP--PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIP--SA 1605
PPP LP PPP + E + + L F+ + P +
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615
Query: 1606 PVLPPPPVHSSIPPPGPVPMGMP----PMSKPPPVQQ 1638
P+ PPP PPP PM P PMS PP V +
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652
Score = 53.1 bits (126), Expect = 3e-06
Identities = 68/249 (27%), Positives = 87/249 (34%), Gaps = 54/249 (21%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPS---LPTSV 573
P P P Q P P PPS P P P PP PP V + TS+
Sbjct: 2437 PSPVTPRFQSPDPYSR------PPSRPQS-RDPFAPLHKPPRPQPPEVAFKAGSLAHTSL 2489
Query: 574 PPPGMPPSLSSAGP--------PPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLS 625
G P +L AGP P PP + S G + PS P + P L
Sbjct: 2490 GAGGFPAALP-AGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLK 2548
Query: 626 SATPPPGIPPP-------------GVPQGIPPQL-------TAAPVPPASSSQSSQVPEK 665
P PG+PPP G PQ + + +P+ P+S S
Sbjct: 2549 PPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLS 2608
Query: 666 P--RPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGES 723
P P++LP P GS P S G S++ +P+ K P G+G S
Sbjct: 2609 PLRPPSVLPPPAPDGSL-------PYLSHGASQRSGITSPVEKREDP------GTGMGSS 2655
Query: 724 SAAPSQPIT 732
A P T
Sbjct: 2656 LATAELPGT 2664
Score = 52.8 bits (125), Expect = 4e-06
Identities = 46/168 (27%), Positives = 61/168 (36%), Gaps = 40/168 (23%)
Query: 1490 PPQESRLQNTSSRPG---------MYPPPGSYRPPPPMGKPPGSIVRPSAPPAR------ 1534
PP R + PG ++PPPG P +G+P ++ P PP
Sbjct: 858 PPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP--ALSEPGEPPLSPLPEEL 915
Query: 1535 --------SSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTN 1586
S P PP P+PPP P PP + P E F D++
Sbjct: 916 PLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL-------EYPFGAKGDSD 968
Query: 1587 DEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634
E L A I P+ PPP + + P P P PM +PP P
Sbjct: 969 PESPL-------AAPILETPISPPPEANCTDPEPVP-PMILPPSPGSP 1008
Score = 52.8 bits (125), Expect = 4e-06
Identities = 74/302 (24%), Positives = 101/302 (33%), Gaps = 66/302 (21%)
Query: 83 PPPLPPP------PVMPGG----GYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQR 132
PPP P P P G G +PP +P P P + K
Sbjct: 2116 PPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKL------------ 2163
Query: 133 DGPPGLVPMELESPPESP-PVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP---AQ 188
P VP ++ P + P + P + P PP PP YP + P PP A
Sbjct: 2164 ---PPQVPAQV--PSQDPFGLAPAYPLEPRFPTAPPTYPP---YPSPTGAPAQPPMLGAS 2215
Query: 189 PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSK-SQLLAP 247
P P + + P + S+ +L L + A P P G K S+ L
Sbjct: 2216 SRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSL-DNLAVPESPGVGGGKASEPLLS 2274
Query: 248 PPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQ 307
PPP V++E L GA + S PS+ T HL L+
Sbjct: 2275 PPPFGESRKALEVKKEEL--GASSPSYGPPNLGFVDSPSSGT-----------HLGGLEL 2321
Query: 308 RTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPE 367
+T P+ K +T A+ P+SP P PP + P PP
Sbjct: 2322 KT-----------------PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPS 2364
Query: 368 EP 369
P
Sbjct: 2365 HP 2366
Score = 52.0 bits (123), Expect = 6e-06
Identities = 102/428 (23%), Positives = 138/428 (32%), Gaps = 140/428 (32%)
Query: 15 PPPP--VPPPPPVALPEASPGPGYSSSTTPAAPSSS--GFMSFREQHLAQLQQLQQMHQK 70
PP P + PPP A P G S TTPA S+S GF+
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIG----SPTTPAGLSTSADGFLK------------------ 2144
Query: 71 QMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPP---PMPPPPGPALSYQKQQQYKHQM 127
PP P P PG + P P P P G A +Y + ++
Sbjct: 2145 -----------PPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFP--- 2190
Query: 128 LHHQRDGPPGLVPMELES-PPESPPVPPGSYMP----PSQSYMPPPQPPPSYYPPTSSQP 182
PP P + P PP+ S P P + + PP P + P++ P
Sbjct: 2191 -----TAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTP--RHQPSTPDP 2243
Query: 183 YLPPAQPS-------------------PSQSPP------------SQSYLAPTPSYSS-- 209
+L P PS P SPP + A +PSY
Sbjct: 2244 FLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPN 2303
Query: 210 ----SSSSSQSYLSHSQSYLP----------SSQASPSRPSQG-----HSKSQLLAPPPP 250
S SS ++L + P +SQ P P G +Q LAP PP
Sbjct: 2304 LGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPP 2363
Query: 251 SAP----PGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQ 306
S P PG+ T +P T + Q P + P+ + + S Q
Sbjct: 2364 SHPDIFRPGSYTDPYAQP-------PLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ 2416
Query: 307 QRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPP 366
++ P TP P+ E P+ P +P + P P PP
Sbjct: 2417 SQSSSQSP----------LTPRPLSAEAFCPS----PVTPRFQSPD--------PYSRPP 2454
Query: 367 EEPQSEDP 374
PQS DP
Sbjct: 2455 SRPQSRDP 2462
Score = 51.6 bits (122), Expect = 8e-06
Identities = 149/685 (21%), Positives = 212/685 (30%), Gaps = 160/685 (23%)
Query: 56 QHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPAL 115
Q QLQQ QQ+ Q+Q Q + Q L L Q L
Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQ-----QLQQQQQQQLQQQQQQL 3955
Query: 116 SYQKQQQYKHQMLHHQRDGPPGLVPME--LESPPESPP----VPPGSYMPPSQSYMPPPQ 169
Q+QQQ + Q Q+ GL+ L SP + + PG P Q + P
Sbjct: 3956 QQQQQQQ-QQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGA 4014
Query: 170 PPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQ 229
P+ Q + PA S + PS P ++ S + ++
Sbjct: 4015 LGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA-------------TE 4061
Query: 230 ASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMT 289
+PS LL P P P +++Q +P P +
Sbjct: 4062 PGEVKPSLSGDSQLLLVQPQPQPQP---SSLQLQP--------------------PLRLP 4098
Query: 290 PQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSE 349
Q+QQQ + +H G + + E +VP P +
Sbjct: 4099 GQQQQQV------------SLLHTAGGGSHGQLGSGSSS---EASSVPHLLAQPSVSLGD 4143
Query: 350 EPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKH 409
+P N L P++P E P ++ Q Q Q G GIM
Sbjct: 4144 QPGSMTQNL-----LGPQQPMLERPMQNNTGPQPPKPGPVLQSGQ----GLPGVGIMPTV 4194
Query: 410 TQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSY 469
QL+ LQ ++ + QLRH QQQQ QL +
Sbjct: 4195 GQLRAQLQG------------VLAKNPQLRHLSPQQQQ-----------------QLQAL 4225
Query: 470 PHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPP 529
+ QLQ+ + +T TQ+ + + Q + G + P
Sbjct: 4226 LMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQ---------E 4276
Query: 530 LPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPP 589
L P P PP LP P P +T P G P PPS P P PS SS P
Sbjct: 4277 LGAGPRPQGPPRLPAP---PGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTE 4333
Query: 590 VLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQ--------G 641
PP+ P P P + PPPG P Q G
Sbjct: 4334 AQLPPT--------------------HPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKG 4373
Query: 642 I----PPQLTAAPVPPASSS---------------QSSQVPEKPRPALLPTPVSFGSAPP 682
+ PP A P SS ++SQ+ K P P + S
Sbjct: 4374 LGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKR 4433
Query: 683 TTYHPPLQSAGPSEQVNSKAPLSKS 707
P+ + G S + P S++
Sbjct: 4434 EANGEPIGAPGTSNHLLLAGPRSEA 4458
Score = 48.5 bits (114), Expect = 7e-05
Identities = 87/383 (22%), Positives = 118/383 (30%), Gaps = 109/383 (28%)
Query: 1481 SEPQMADHL--PPQESRLQNTSSRPGMYPPPGSYR-----------PPPPMG--KPPGSI 1525
S P A L PP+ES + M PPP + R PPP PP
Sbjct: 564 SPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEA 623
Query: 1526 VRPSAPPARSSVPVTRPPV--PIPPPPPPPPLPP--------PPPVIKPQTSAVEQERWD 1575
R S PP S P++ PP P+ PPP L P PPP P + E+
Sbjct: 624 SRLSPPPEDS--PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE---- 677
Query: 1576 EDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKP-- 1633
+P PPP PPP P PP P
Sbjct: 678 -----------------------------SPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708
Query: 1634 PPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDRE 1693
PP + + + +P E L PLPE G + R E
Sbjct: 709 PPPE-------------DSLMSLPLEESPLL---PLPEEPQLCPRSEGP---HLSPRPEE 749
Query: 1694 PYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDH 1753
P+ R E H + + +P + + ++
Sbjct: 750 PHLS------------PRPEEPHLSPQAEEPHL---------SPQPEEPCLCAVPEEPHL 788
Query: 1754 SSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSLSHQPPPA--PRVE 1811
S G P + P E P + PEE P P SH P + P +
Sbjct: 789 SPQAEGPHLSPQPEELHLSPQTEEPHL-----SPVPEEPCLSPQPEESHLSPQSEEPCLS 843
Query: 1812 KKPESKNVDDILKPPGRESRPER 1834
+PE ++ L+ P RPE+
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEK 866
Score = 48.1 bits (113), Expect = 9e-05
Identities = 56/204 (27%), Positives = 76/204 (37%), Gaps = 20/204 (9%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQ--HLA--QLQQLQQM-HQK 70
P P P P + + PG G + G ++ Q HL+ Q QQLQ + Q+
Sbjct: 4170 PQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQR 4229
Query: 71 QMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMP-PPPGPALSYQKQQQYKHQMLH 129
Q+Q PP P P G QP P P GP Q+
Sbjct: 4230 QLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL---QELGAGPRPQGP 4286
Query: 130 HQRDGPPG-------LVPMELESPPESPPVP--PGSYMPPSQSYMPPPQPPPSYYPPTSS 180
+ PPG L P+ PP SP P P PS Q PP++ P +
Sbjct: 4287 PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH--PGTP 4344
Query: 181 QPYLPPAQPSPSQSPPSQSYLAPT 204
+P P +P P + P+ + LA T
Sbjct: 4345 KPQGPTLEPPPGRVSPAAAQLADT 4368
Score = 45.4 bits (106), Expect = 6e-04
Identities = 77/305 (25%), Positives = 99/305 (32%), Gaps = 90/305 (29%)
Query: 14 YPPPP----VPPPPPVALPEASPG---PGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQ 66
YPP P P PP+ + PG PG +T P P
Sbjct: 2196 YPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPR-------------------- 2235
Query: 67 MHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQ 126
HQ P P PG G G P PPP G + +K + K +
Sbjct: 2236 -HQPSTPDPFLKPRCPSLDNLAVPESPGVGGGK-ASEPLLSPPPFGES---RKALEVKKE 2290
Query: 127 MLHHQRD--GPPGLV------------PMELESP---------------PESPPV----- 152
L GPP L +EL++P P+SP +
Sbjct: 2291 ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQ 2350
Query: 153 --PPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS----PPSQSYLAP--- 203
PP + PS P P SY P + P P QP P +S PP P
Sbjct: 2351 EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSR 2410
Query: 204 TPSYSSSSSSSQSYLS----HSQSYLPSS-----------QASPSRPSQGHSKSQLLAPP 248
P+ S SSSQS L+ ++++ PS PSRP + L PP
Sbjct: 2411 VPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP 2470
Query: 249 PPSAP 253
P P
Sbjct: 2471 RPQPP 2475
Score = 45.1 bits (105), Expect = 8e-04
Identities = 66/296 (22%), Positives = 104/296 (35%), Gaps = 70/296 (23%)
Query: 1415 PMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMV------LSQRQHEIILKAAQELKMLRE 1468
PM E ++ + L S QGL GV + L + ++ K Q + +
Sbjct: 4158 PMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQ 4217
Query: 1469 QKEQLQK--MKDFGSEPQMADHLPPQESRLQNTSSRPGMY---PPPGSYRPPPPMG---- 1519
Q++QLQ M+ + Q PP + TS G+ P G + P P G
Sbjct: 4218 QQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF-PGPQTGPLQE 4276
Query: 1520 -----KPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERW 1574
+P G P+ P A S+ PV P P PPP P P + P
Sbjct: 4277 LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP---------- 4326
Query: 1575 DEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPV----------- 1623
+S+ +E P+ P P P + PPPG V
Sbjct: 4327 -----------------SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTL 4369
Query: 1624 -PMGMPPMSKP-------PPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPE 1671
G+ P P P Q ++ GH ++ + +P +++++ +P E
Sbjct: 4370 FSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNG---QVVPEASQLSIKQEPREE 4422
Score = 44.3 bits (103), Expect = 0.001
Identities = 29/87 (33%), Positives = 34/87 (39%), Gaps = 4/87 (4%)
Query: 505 NMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPV 564
N+ N + +S PPP P PPP P P P PP+ P V P P PP P P+
Sbjct: 4897 NVSNLDVRQLSAPPPEEP---SPPPSPLAPSPASPPT-EPLVELPTEPLAEPPVPSPLPL 4952
Query: 565 MPPSLPTSVPPPGMPPSLSSAGPPPVL 591
P PP PP L
Sbjct: 4953 ASSPESARPKPRARPPEEGEDSRPPRL 4979
Score = 43.5 bits (101), Expect = 0.002
Identities = 83/376 (22%), Positives = 127/376 (33%), Gaps = 58/376 (15%)
Query: 54 REQHLAQLQQLQQMHQKQM-----------QCVLQPHHLPPPPLPPPPVMPGGGYGDWQP 102
++Q AQLQ QQ Q+Q Q + PH P L G +
Sbjct: 3263 KQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQ 3322
Query: 103 P--PPPMPPPPGPALSYQKQ-------QQYKHQMLHHQRDGPPGLVPMELESPPESP--- 150
P P P+ P PA + Q++ + ML Q G GLVP + P S
Sbjct: 3323 PGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPM 3382
Query: 151 -PVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSS 209
+PP M P Q M Q S++P T + P + +
Sbjct: 3383 GTMPPSMCMKPQQLAM-QQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQ 3441
Query: 210 SSSSSQSYLSHSQSYLPSSQAS--PSRPSQGH---SKSQLLAPPPPSAPPGNKTTVQQEP 264
S ++ Q L + + S PS Q H Q + PS P N T Q
Sbjct: 3442 GSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQ-- 3499
Query: 265 LESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPG-HKKGPVVA 323
G N++ ++Q ++ ++ Q LL +Q + G H+K
Sbjct: 3500 ---GVINEADQRQY--------------EEWLFHTQQLLQMQLKVLEEQIGVHRKSRKAL 3542
Query: 324 KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEE---DARL 380
K+ A + PE+ + + + ++ L Q ++ + R
Sbjct: 3543 -----CAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRN 3597
Query: 381 KQLQAAAAHWQQHQQH 396
KQ Q QQ QQH
Sbjct: 3598 KQQQQQQQQQQQQQQH 3613
Score = 42.4 bits (98), Expect = 0.005
Identities = 44/174 (25%), Positives = 56/174 (32%), Gaps = 40/174 (22%)
Query: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPP 1550
P+ES L S P + P P P + KPP S RP PP +P+ PPP
Sbjct: 828 PEESHLSPQSEEPCLSPRPEESHLSPELEKPPLS-PRPEKPPEEPGQCPAPEELPLFPPP 886
Query: 1551 PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPP 1610
P L P L SE P P L P
Sbjct: 887 GEPSLSPL--------------------------------LGEPALSE----PGEPPLSP 910
Query: 1611 PPVHSSIPPPGPV---PMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGER 1661
P + P G P MPP PPP+ + +S + P+G +
Sbjct: 911 LPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAK 964
Score = 42.4 bits (98), Expect = 0.005
Identities = 28/77 (36%), Positives = 35/77 (45%), Gaps = 13/77 (16%)
Query: 613 TAPPPVMPLPPLSSATPPPGIPP-------PGVPQGIPPQLTAAPVPPASSSQSSQVPEK 665
+APPP P PP S P P PP P P PP +P+P ASS +S+ +
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPP--VPSPLPLASSPESA----R 4960
Query: 666 PRPALLPTPVSFGSAPP 682
P+P P S PP
Sbjct: 4961 PKPRARPPEEGEDSRPP 4977
Score = 38.9 bits (89), Expect = 0.055
Identities = 19/57 (33%), Positives = 27/57 (47%)
Query: 330 VKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAA 386
++ ++ P ++P P EE PL PP EE P PPE + P E+ L A
Sbjct: 426 LEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA 482
Score = 38.9 bits (89), Expect = 0.055
Identities = 44/162 (27%), Positives = 58/162 (35%), Gaps = 28/162 (17%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP 1549
PP E+ + P M PP P P+G ++ P P + + P PP
Sbjct: 984 PPPEANCTDPEPVPPMILPPS---PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPS 1040
Query: 1550 ---PPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAP 1606
PP PL P P + P V +DE L+ E ++E + P P
Sbjct: 1041 QCSPPALPLSVPSP-LSPIGKVV--------------GVSDEAELH-EMETEKVSEPECP 1084
Query: 1607 VLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDY-GHGRD 1647
L P S P P PMG P P D+ G G D
Sbjct: 1085 ALEP-----SATSPLPSPMGDLSCPAPSPAPALDDFSGLGED 1121
Score = 38.5 bits (88), Expect = 0.072
Identities = 106/488 (21%), Positives = 149/488 (30%), Gaps = 155/488 (31%)
Query: 76 LQPHHLPPP----PLPP--PPVMPGGGYGDWQPPPPPMP---PPP--------------- 111
L+P PP P PP P + G Y D PP P PPP
Sbjct: 2347 LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSD 2406
Query: 112 -------GPALSYQKQQQYKHQMLHHQRDGPPGLVP-MELESPPESPPVPPGSYMPPSQS 163
P Q + L + P + P + P PP P S P +
Sbjct: 2407 PFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPL 2466
Query: 164 YMPP-PQPP-----------------------------------PSYYPP---------- 177
+ PP PQPP PS PP
Sbjct: 2467 HKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGA 2526
Query: 178 --------------TSSQPYLPPAQPSPSQSPPS--QSYLAPTPSYSSSSSSSQSYLSHS 221
+P L P P P PP S+ P P+ S+ +Y +
Sbjct: 2527 FVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQST--NYTVAT 2584
Query: 222 QSYLPS-SQASPSRPSQGHSKS-QLLAPP---PPSAPPG----------------NKTTV 260
++ PS S PS S G S L PP PP AP G +
Sbjct: 2585 GNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEK 2644
Query: 261 QQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSL---QQRTKVHLPGHK 317
+++P + +T + +P S ++ E ++ RQ L L QQ + L K
Sbjct: 2645 REDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEK 2704
Query: 318 KGPVVA-----------KDTPEPVKEEV---------TVPATSQVPESPSSEEPPLP--- 354
+ A + P E++ T +S V PS P+
Sbjct: 2705 ETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPG 2764
Query: 355 --PPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQL 412
P ++ + P PP P S D +QL + + Q Y G + Q
Sbjct: 2765 SFPSDDRLSRPPPPATPSS----MDVNSRQLVGGSQAFYQRA------PYPGSLPLQQQQ 2814
Query: 413 QQILQQYQ 420
QQ+ QQ Q
Sbjct: 2815 QQLWQQQQ 2822
Score = 38.5 bits (88), Expect = 0.072
Identities = 20/67 (29%), Positives = 28/67 (41%)
Query: 592 PPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPV 651
PPP S P P+ P P+ T P +P PL+ P +P P+ P+ A P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
Query: 652 PPASSSQ 658
S+
Sbjct: 4969 EEGEDSR 4975
Score = 38.1 bits (87), Expect = 0.094
Identities = 31/123 (25%), Positives = 43/123 (34%), Gaps = 6/123 (4%)
Query: 1517 PMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDE 1576
P+GK + P +P+ PP P PPP P PP + S +E
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477
Query: 1577 DSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPV 1636
L + + +S + P L PPP S P P+ P S P P
Sbjct: 478 PLPEALHLSRPLE------ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPA 531
Query: 1637 QQT 1639
+T
Sbjct: 532 LET 534
Score = 38.1 bits (87), Expect = 0.094
Identities = 90/393 (22%), Positives = 125/393 (31%), Gaps = 77/393 (19%)
Query: 531 PTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPV---------MPPSLPTSVPPPGMPPS 581
P PP VLPP P +P G+ PV M SL T+ P P
Sbjct: 2609 PLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPG 2668
Query: 582 LSSAGPPPV----------------------LPPPSLSSAGPPPVLPPPSLSSTAPPPVM 619
+S + L ++A + PP S A P
Sbjct: 2669 MSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG-SWGAEPSSP 2727
Query: 620 PLPPLSSA-TPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPV--- 675
LS TP G G+PP + P+ S S +P P P+ +
Sbjct: 2728 AFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVN 2787
Query: 676 ---------SFGSAPPTTYHPPLQSAGPS--EQVNSKAPLSKSALPYSSFSSDQGLGESS 724
+F P PLQ +Q + A S + F S G
Sbjct: 2788 SRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGR 2847
Query: 725 AAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCE-GPRPKGP 783
A P+ + G +P P GP +F +L + G P G
Sbjct: 2848 QALGSPLAGISTRLPGPGEPVPGPA--------------GPAQFIELRHNVQKGLGPGGT 2893
Query: 784 RFEGNRPDGPRPRY-----EGH--PAEGTK--SKWGMIPRGPASQFYITPSTSLSPRQSG 834
F G P RPR+ + H EG + + G+ P+ P++ + SL P
Sbjct: 2894 PFPGQGPP-QRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT--- 2949
Query: 835 PQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLA 867
P KGP G + +P S E G PLA
Sbjct: 2950 PHTKGPTLPTGLELVNRPPSSTE--LGRPNPLA 2980
Score = 38.1 bits (87), Expect = 0.094
Identities = 31/135 (22%), Positives = 55/135 (40%), Gaps = 11/135 (8%)
Query: 1448 LSQRQHEIILKAAQELKMLREQKEQL----QKMKDFGSEPQMADHLPPQESRLQNTSSRP 1503
L Q+Q + + + Q+L+ ++Q++Q Q+ + G Q L PQ+ + Q + P
Sbjct: 3940 LQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGP 3999
Query: 1504 GM-------YPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP 1556
GM + PG+ P + + V P+ + P T P+ P +
Sbjct: 4000 GMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059
Query: 1557 PPPPVIKPQTSAVEQ 1571
P +KP S Q
Sbjct: 4060 TEPGEVKPSLSGDSQ 4074
Score = 38.1 bits (87), Expect = 0.094
Identities = 34/116 (29%), Positives = 47/116 (40%), Gaps = 16/116 (13%)
Query: 1466 LREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSS---RPGMYPPPGSYRPPPPMGKPP 1522
L+ Q + L +K P+ P Q S N S+ R PPP PPP P
Sbjct: 4869 LKSQLDILSLLKQESPAPEP----PTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS 4924
Query: 1523 GSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP--PPPPVIKPQTSAVEQERWDE 1576
P++PP V + P P+ PP P PLP P +P+ A E ++
Sbjct: 4925 -----PASPPTEPLVEL--PTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGED 4973
Score = 37.4 bits (85), Expect = 0.16
Identities = 44/160 (27%), Positives = 57/160 (35%), Gaps = 25/160 (15%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSA-PPARSSVPVTRPPVPIP 1547
L P+ S+++ S G+ P PPP P P P + P +PP+
Sbjct: 2331 LTPRASQVEPQSPGLGLRPQ----EPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPR 2386
Query: 1548 PPPPPPP---LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPS 1604
P PPPP PP + S V + S + L S A PS
Sbjct: 2387 PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSS--------SQSPLTPRPLSAEAFCPS 2438
Query: 1605 APVLP--PPPVHSSIPPPGP------VPMGMPPMSKPPPV 1636
PV P P S PP P P+ PP +PP V
Sbjct: 2439 -PVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEV 2477
Score = 37.4 bits (85), Expect = 0.16
Identities = 39/153 (25%), Positives = 53/153 (34%), Gaps = 42/153 (27%)
Query: 1535 SSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSE 1594
S++ V + P P P PPP P P P T + E
Sbjct: 4899 SNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLV-----------------------E 4935
Query: 1595 FKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPM----SKPPPVQQ------------ 1638
+E A P PV P P+ SS P P PP S+PP +++
Sbjct: 4936 LPTEPLAEP--PVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRLRLL 4993
Query: 1639 -TVDYGHGRDISTNKVEQIPYGERITLRPDPLP 1670
T+ G GR +V + LRPD +P
Sbjct: 4994 LTIQKGSGRQEDEREVAEFMEQLGTALRPDKVP 5026
Score = 37.4 bits (85), Expect = 0.16
Identities = 28/74 (37%), Positives = 34/74 (45%), Gaps = 6/74 (8%)
Query: 535 PPVLPPSLPP-PVMP-PALPATVPPPGMP-PPVMPPSLPTSVPPPGMPPSLSSAGPPPVL 591
PP PS PP P+ P PA P T P +P P+ P +P+ +P P SA P P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSP---ESARPKPRA 4965
Query: 592 PPPSLSSAGPPPVL 605
PP PP L
Sbjct: 4966 RPPEEGEDSRPPRL 4979
Score = 37.0 bits (84), Expect = 0.21
Identities = 45/179 (25%), Positives = 63/179 (35%), Gaps = 49/179 (27%)
Query: 1481 SEPQMAD-----HLPPQES---------RLQNTSSRPGMYP------PPGSYRPPPPMGK 1520
S PQ D H PP+ L +TS G +P P G P G+
Sbjct: 2455 SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQ 2514
Query: 1521 PPGSIVRPSA-------PPARSSVPVTRPPVPIPPPPPPPPLPPP----------PPVIK 1563
PP + P P R + P + PP P P LPPP P + K
Sbjct: 2515 PPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGK 2574
Query: 1564 PQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP 1622
PQ++ + + G +S E+ + +P+ PP S +PPP P
Sbjct: 2575 PQSTNYTVATGN------FHPSGSPLGPSSGSTGESYGL--SPLRPP----SVLPPPAP 2621
Score = 37.0 bits (84), Expect = 0.21
Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 7/71 (9%)
Query: 554 TVPPPGMPPPVMPPSLPTSVPPPGMP----PSLSSAGPPPVLPPP---SLSSAGPPPVLP 606
+ PPP P P P P+ PP P P+ A PP P P S SA P P
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRAR 4966
Query: 607 PPSLSSTAPPP 617
PP + PP
Sbjct: 4967 PPEEGEDSRPP 4977
Score = 35.8 bits (81), Expect = 0.46
Identities = 48/197 (24%), Positives = 69/197 (35%), Gaps = 50/197 (25%)
Query: 1458 KAAQELKMLREQKE-QLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPP 1516
+AA + +++Q E Q+ K G + D P R+ P PG+ PP
Sbjct: 2068 RAAHRINKVQKQAESQINKQTKVGDIARKTDR-PALHLRIP---------PQPGALGSPP 2117
Query: 1517 PMGKPPGSIVRPSAPP--ARSSVPVTRPPVPIPPPPPPP-----PLPPPPPVIKPQTSAV 1569
P P I P+ P + S+ +PP P P P LPP P P
Sbjct: 2118 PAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVP----- 2172
Query: 1570 EQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPP 1629
+ D GL P+ P+ P P PP P P G P
Sbjct: 2173 ---------------SQDPFGL----------APAYPLEPRFPTAPPTYPPYPSPTGAP- 2206
Query: 1630 MSKPPPVQQTVDYGHGR 1646
++PP + + G G+
Sbjct: 2207 -AQPPMLGASSRPGAGQ 2222
Score = 35.8 bits (81), Expect = 0.46
Identities = 94/411 (22%), Positives = 136/411 (33%), Gaps = 65/411 (15%)
Query: 8 YGGSSHYPPPPVPPP-PPVALPEASPG----------------PGYSSSTTPAAPSSSGF 50
YG S PP +PPP P +LP S G PG ++ A G
Sbjct: 2605 YGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGT 2664
Query: 51 MSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPP 110
L+Q + +Q +++++ +L + L G PP P
Sbjct: 2665 QDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEP 2724
Query: 111 PGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQP 170
PA + Q + GL P +L P + PGS+ + PPP
Sbjct: 2725 SSPAFEQLSRGQTPFAGT-QDKSSLVGLPPSKL----SGPILGPGSFPSDDRLSRPPPPA 2779
Query: 171 PPSYYPPTS------SQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSY 224
PS S SQ + A P P P Q +++++S +
Sbjct: 2780 TPSSMDVNSRQLVGGSQAFYQRA-PYPGSLPLQQQQQQLWQQQQATAATSMRF------- 2831
Query: 225 LPSSQASPSRPSQGHSKSQLLAP--------PPPSAP-PGNKTTVQQEPLESGAKNKSTE 275
S PS P + L +P P P P PG Q L +
Sbjct: 2832 -AMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIEL------RHNV 2884
Query: 276 QQQAAP--EPDPSTMTPQEQQQYWYRQ--HLLS---LQQRTKVHLPGHKKGPVVAKDT-- 326
Q+ P P P PQ + Y + H L+ L+ LP K A +
Sbjct: 2885 QKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNN 2944
Query: 327 ---PEPVKEEVTVPATSQ-VPESPSSEEPPLPPPNEEVPPPLPPEEPQSED 373
P P + T+P + V PSS E P P LP E+P+ +D
Sbjct: 2945 SLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDD 2995
Score = 35.8 bits (81), Expect = 0.46
Identities = 59/233 (25%), Positives = 76/233 (32%), Gaps = 50/233 (21%)
Query: 3 PNWGRYGGSSHYPPPPVPPPPPVALPEASPGPG-YSSSTTPAAPSS---------SGFMS 52
P G SS PP P+ P + P S PA PSS G +
Sbjct: 2738 PFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQA 2797
Query: 53 FREQ-----HLAQLQQLQQMHQKQMQCVLQPHHLPP----PPLPPPPV------MPGGGY 97
F ++ L QQ QQ+ Q+Q P P P + P G
Sbjct: 2798 FYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGI 2857
Query: 98 GDWQPPP-PPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGS 156
P P P+P P GPA Q + + + GL P P + PP P
Sbjct: 2858 STRLPGPGEPVPGPAGPA-----------QFIELRHNVQKGLGPGGTPFPGQGPPQRPRF 2906
Query: 157 YMPPSQSYMPPPQPPPSYYPPTSSQPY----LPPAQPSPSQSPPSQSYLAPTP 205
Y P P P + LPP +PS +P + L PTP
Sbjct: 2907 Y---------PVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTP 2950
Score = 34.7 bits (78), Expect = 1.0
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 19/83 (22%)
Query: 1493 ESRLQNTSSRPGMYPPPG---SYRPPPPMGKPP--------------GSIVRPSAPPARS 1535
E L+ +PG+ PP G + P P +GKP GS + PS+
Sbjct: 2544 EPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGE 2603
Query: 1536 SVPVT--RPPVPIPPPPPPPPLP 1556
S ++ RPP +PPP P LP
Sbjct: 2604 SYGLSPLRPPSVLPPPAPDGSLP 2626
Score = 34.3 bits (77), Expect = 1.4
Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 5/64 (7%)
Query: 142 ELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYL 201
+L +PP P PP S + PS P PP ++P P PSP S
Sbjct: 4905 QLSAPPPEEPSPPPSPLAPS-----PASPPTEPLVELPTEPLAEPPVPSPLPLASSPESA 4959
Query: 202 APTP 205
P P
Sbjct: 4960 RPKP 4963
Score = 33.5 bits (75), Expect = 2.3
Identities = 44/190 (23%), Positives = 61/190 (32%), Gaps = 8/190 (4%)
Query: 1491 PQESRLQNTSSRPGMYPPPGSYRPPP--PMGKP--PGSIVRPSAPPARSSVPVTRPPVPI 1546
P + + SSRPG P + PP P +P P ++P P + P V
Sbjct: 2206 PAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGG 2265
Query: 1547 PPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTN--DEQGLNSEFKSETAAIPS 1604
P PPP + ++E YG + D + P
Sbjct: 2266 GKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPD 2325
Query: 1605 APVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGE-RIT 1663
P P S + P P +G+ P PP DI PY + +T
Sbjct: 2326 VFKAPLTPRASQVEPQSP-GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLT 2384
Query: 1664 LRPDPLPERS 1673
RP P P S
Sbjct: 2385 PRPQPPPPES 2394
Score = 33.5 bits (75), Expect = 2.3
Identities = 66/333 (19%), Positives = 113/333 (33%), Gaps = 59/333 (17%)
Query: 146 PPESPPVPPGSYMPPSQSYMPPPQPP-------PSYYPPTSSQPYLPPAQPSPSQS---P 195
P E PP + P S +P +P PS T + P + PA + S
Sbjct: 3096 PEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSLGLGLK 3155
Query: 196 PSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPG 255
P QS + + + S S + ++ ++ P+ L P P + PG
Sbjct: 3156 PGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAH----------LLTPSPLSGPG 3205
Query: 256 NKTTVQQEPLESGAKNKSTEQQQAAPEPDP--------------STMTPQEQQQYWYRQH 301
+ +++ LESGA + E D + E+++ +Q
Sbjct: 3206 GSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQ 3265
Query: 302 LLS-------LQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLP 354
L + QQ+ + H GP A P + Q+ + P
Sbjct: 3266 LSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQP-- 3323
Query: 355 PPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQ 414
+P PL P +P + L+Q A + +Q H + Q+ G Q
Sbjct: 3324 ----GLPQPLMPTQPPAH------ALQQRLAPSMAMVSNQGHMLSGQHGG------QAGL 3367
Query: 415 ILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQ 447
+ QQ Q + + TM M ++ ++ QQ
Sbjct: 3368 VPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQ 3400
Score = 33.5 bits (75), Expect = 2.3
Identities = 30/100 (30%), Positives = 39/100 (39%), Gaps = 20/100 (20%)
Query: 106 PMPPPPGPALSYQKQQQYKHQMLH---HQRDGPPGLVPMELESP----PESPPVPPGSYM 158
P P PP Q Y + + + Q PP P SP P SPP P +
Sbjct: 4884 PAPEPP-------TQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVEL 4936
Query: 159 PPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQ 198
P++ PP P P P +S P A+P P PP +
Sbjct: 4937 -PTEPLAEPPVPSPL---PLASSP--ESARPKPRARPPEE 4970
Score = 32.7 bits (73), Expect = 3.9
Identities = 25/81 (30%), Positives = 32/81 (39%), Gaps = 10/81 (12%)
Query: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLS 625
PP S PP + PS +S P++ P+ A PP P P SS P S
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASS----------PES 4958
Query: 626 SATPPPGIPPPGVPQGIPPQL 646
+ P PP PP+L
Sbjct: 4959 ARPKPRARPPEEGEDSRPPRL 4979
Score = 32.3 bits (72), Expect = 5.1
Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 13/103 (12%)
Query: 141 MELESPPESPPVPPG-----SYMPPSQSYMPPPQ---PPPSYYPPTSSQPYLPPAQPSPS 192
++ ESP PP S + Q PPP+ PPPS P+ + P P P+
Sbjct: 4879 LKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPT 4938
Query: 193 QSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRP 235
+ +P P SS S+ + P + SRP
Sbjct: 4939 EPLAEPPVPSPLPLASSPESARPKPRAR-----PPEEGEDSRP 4976
Score = 32.0 bits (71), Expect = 6.7
Identities = 26/127 (20%), Positives = 49/127 (38%), Gaps = 5/127 (3%)
Query: 813 PRGPASQFYITPSTSLSPRQSGPQWKG---PKPAFGQQHQQQPKSQAEPLSGNKEPLADT 869
P+GP Q +T S LS Q Q +G + QQ QQQ + Q + L +
Sbjct: 3820 PQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQS 3879
Query: 870 SSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQE--PPKSEVSEGPVEPSNWDQN 927
+ K+ + ++ + Q + L QQ+ + ++ + ++ Q
Sbjct: 3880 LMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQ 3939
Query: 928 VQSMETQ 934
+Q + Q
Sbjct: 3940 LQQQQQQ 3946
Score = 31.6 bits (70), Expect = 8.8
Identities = 32/157 (20%), Positives = 60/157 (38%), Gaps = 22/157 (14%)
Query: 277 QQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTV 336
+Q +P P+P T Q+ Y ++ +L R P + P P P+
Sbjct: 4880 KQESPAPEPPT-------QHSYTYNVSNLDVRQLSAPPPEEPSP-----PPSPLAPSPAS 4927
Query: 337 PATSQVPESPSSE--EPPLPPP------NEEVPPPLPPEEPQSEDPEEDARLKQLQAAAA 388
P T + E P+ EPP+P P E P P+ + RLK+ +
Sbjct: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWK--GV 4985
Query: 389 HWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQP 425
W++ + + G + ++ + ++Q ++P
Sbjct: 4986 RWKRLRLLLTIQKGSGRQEDEREVAEFMEQLGTALRP 5022
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 127 bits (318), Expect = 2e-28
Identities = 193/774 (24%), Positives = 258/774 (33%), Gaps = 154/774 (19%)
Query: 149 SPPVPPGSYMPPSQSYMPPPQPPPSYYPPT-------SSQPYLPPAQPSPS-QSPPSQSY 200
SP + S ++ +P P P PPT SS +PSP+ + PS
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP---SRPSQGHSKSQLLAPPPPSAPPGNK 257
P+ S SSS+ S ++S PS++ +P + PSQ K PP PP
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSG-PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
Query: 258 TTVQQEPLES---------GAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQR 308
PL S G K + A P P+T+ P S
Sbjct: 292 AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP-------------SPPLA 338
Query: 309 TKVHL-PGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPL--PPPNEEVPPPLP 365
T + L P P + P P PAT PS PP+ PP + +PP
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSP-------PATPPSQAPPSMTTPPMQAPPSLQTIPPIQV 391
Query: 366 PEE---PQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQI 422
P P + P L LQA + Q F + Q Q L +
Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSF----LTMSPRQTQASLTSPSRP 447
Query: 423 IQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQW 482
PP + + L Q + H L + Q
Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI-----HPLQALSSLASHSPQA 502
Query: 483 KTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSL 542
M ++ S Q +++ PP S PPPL T P+ P L
Sbjct: 503 PLSSLIMPPLETQSSLAPPSLQTPP----ASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558
Query: 543 PPPVMPPALPATVPPPGM--PPPVMPPSLPTSVPPPGMPPSLSS--------------AG 586
P P P PP + PPP P S+ T PPP PP+L+S A
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIAT--PPPQAPPALASPPLQGLPSPPLSPLAT 616
Query: 587 PPPVLPP----PSLSSAGPPPVLPPPSLSST------------------APPPVMPL--- 621
PPP PP P L + PP PP S +T +PPP P+
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676
Query: 622 ------PPLSSATPPPGIPPPGV---PQGIPPQLTAAP-----------VPPASSSQSSQ 661
PP+S + PP PP + P +PP A+P PP ++ Q
Sbjct: 677 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 736
Query: 662 VPEKP--RPALLPTPVSFGSAPPTTYHPPLQ-------------SAGPSEQVN---SKAP 703
VP P P + P+ PP PPLQ A P Q + P
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796
Query: 704 LSKSALPYSSFSSDQGLGESSAAPSQPITAVKDM--PVRSGGLL---PDPPRSSYLESPR 758
L P +SF S++ P P+ PV + LL P PP S L++PR
Sbjct: 797 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 856
Query: 759 GPRFDGPRRFEDLGSR-----CEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKS 807
P GP G R GP P R + G P GH + T +
Sbjct: 857 RPPTPGPDTSVS-GPRLTLALAPGPPPPPSRSPSSTLSG--PDLAGHSSSATST 907
Score = 93.2 bits (230), Expect = 2e-18
Identities = 212/879 (24%), Positives = 282/879 (32%), Gaps = 195/879 (22%)
Query: 82 PPPPLPPPPVMP------GGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135
P P PPPPV P G + P G A + R GP
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP----------RAGP 79
Query: 136 PGLVPMELESPPESPPVPP-GSYMPPSQSYMPPPQPPPSYYPPTSSQ-PYLPPAQPSPSQ 193
+P PP G PP+++ P P P T+ P ++
Sbjct: 80 TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 194 SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAP 253
++ P S+ S+ ++ S PS + +R S+ L P PSA
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP--AMARRSRAAGTEVGLPRPAPSAR 197
Query: 254 PGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHL 313
P + P E K+ S+ + + EP P+ R SL
Sbjct: 198 P-------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 314 PGHKKGPVVAKDTPEPVKE---------------EVTVPATSQVPE-SPSSEEP------ 351
+ GP A+ TP +VT P P P S P
Sbjct: 251 SPARSGP-SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
Query: 352 ------PLPPPNE---EVPPPLPPEEPQS-------EDPEEDARLKQLQAAAAHWQQHQQ 395
P+PPP+ +P LPP P + P L+ L + A
Sbjct: 310 SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA------- 362
Query: 396 HRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEW 455
Q +Q PP +QT+ +Q+ H
Sbjct: 363 -------------TPPSQAPPSMTTPPMQAPPSLQTIP-PIQVPH--------------- 393
Query: 456 EREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMS 515
L L + P L + ++AT S+L Q S
Sbjct: 394 ----SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449
Query: 516 MPPPFVPYSQMPPPLPTMPP------PVLPP----------------------------- 540
PP P Q P LP PP P + P
Sbjct: 450 TPPDSPPL-QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508
Query: 541 --------SLPPPVM--PPALPATVP----PPGMPPPVMPPSLPTSVP----PPGMPPSL 582
SL PP + PPA T P P PPP+ S P + P PP P
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 583 SSAGPPPVL--PPPSLSSAGPPPVLPPPSLSSTAPPPV--MPLPPLSS-ATPPPGIPPPG 637
A P P+ PP + SS PP PP+L+S PP+ +P PPLS ATPPP PP
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALAS---PPLQGLPSPPLSPLATPPPQAPP-- 623
Query: 638 VPQGIPPQLTAAPVPPAS------SSQSSQVPEKPRPALLPTPVSFGSAPP--TTYHPPL 689
+PP L A P PPAS ++ S Q P LL P S +PP + PP
Sbjct: 624 -XLALPP-LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 690 Q-SAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDP 748
PS S+AP S +A P S S + + P A + + P P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741
Query: 749 PRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGP--RPRYEGHPAEGTK 806
P S P P P R L P P + P P +P + PA T
Sbjct: 742 PAS----PPMSPSATPPPRVPPL--LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATP 795
Query: 807 SKWGMIPRGPAS---QFYITPSTSL--SPRQSGPQWKGP 840
+P PAS Q +PS SL SP + P P
Sbjct: 796 PLQA-LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833
Score = 84.7 bits (208), Expect = 9e-16
Identities = 95/370 (25%), Positives = 120/370 (32%), Gaps = 56/370 (15%)
Query: 13 HYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
H PP P P P+ P P ++ P PSS + LQ + +
Sbjct: 557 HLETPPCPAPCPLQAP-----PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPL 611
Query: 73 QCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQR 132
+ P PP L PP+ PP PP PP P + Q + + H
Sbjct: 612 SPLATPPPQAPPXLALPPLQA--------PPSPPASPPLSPLAT--PSPQAPNALAVHLL 661
Query: 133 DGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQP--S 190
P P SPP P P + P S S PP Q PPS P P PPA P S
Sbjct: 662 QAPFSPPP----SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717
Query: 191 PSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPP 250
PS +PP Q AP P + P Q PS P+ A PPP
Sbjct: 718 PSATPPPQ---APPPLAA-----------------PPLQVPPSPPASPPMSPS--ATPPP 755
Query: 251 SAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTK 310
PP Q P A + + P+ P+ TP L
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP-----------LQALPSPP 804
Query: 311 VHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQ 370
PG A P+ P V +P + PP PP + + P P P
Sbjct: 805 ASFPGQAPFSPSASLPMSPLA--TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 862
Query: 371 SEDPEEDARL 380
+ RL
Sbjct: 863 PDTSVSGPRL 872
Score = 82.4 bits (202), Expect = 4e-15
Identities = 124/469 (26%), Positives = 170/469 (36%), Gaps = 92/469 (19%)
Query: 516 MPPPFVPYSQMPPPLPTMPPPVLP-PSLPP-PVMPPALPATVPPPGMPPPVMPPSLPTSV 573
+PPP + +P LP PP P P PP P PP+L PP PP PPS+ T
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT-- 374
Query: 574 PPPGMPPSLSSAGPPPVLPPPSLSS----AGPPPV----------LPPPSLSST----AP 615
PP PPSL + PP+ P SL+S A P P+ L P+L +T
Sbjct: 375 PPMQAPPSLQTI--PPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432
Query: 616 PPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPV 675
P L+S + P PP P P L A+ PP +S S PA+ P
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS--PPLQTSLS--------PAVSPL-- 480
Query: 676 SFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPS--QPITA 733
+ P T H PLQ+ + +APLS +P S S A PS P +
Sbjct: 481 ----SSPLTIH-PLQALSSLASHSPQAPLSSLIMPPLETQS------SLAPPSLQTPPAS 529
Query: 734 VKDMPVRSGGLLPDPP--------RSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRF 785
+ P+ + L PP + +LE+P P P + S P P+ P
Sbjct: 530 LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP---APCPLQAPPSPLTTPPPETPSS 586
Query: 786 EGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFG 845
P P P +G PS LSP + P P A
Sbjct: 587 IATPPPQAPPALASPPLQG------------------LPSPPLSPLATPPPQAPPXLALP 628
Query: 846 QQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDS 905
+ PLS PLA T S Q N ++A + + +
Sbjct: 629 PLQAPPSPPASPPLS----PLA-TPSPQAPN--------ALAVHLLQAPFSPPPSPPVQA 675
Query: 906 QQEPPKS-EVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVP 953
PP S VS PS ++ + Q+ + + P+ + P P
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
Score = 80.9 bits (198), Expect = 1e-14
Identities = 78/275 (28%), Positives = 101/275 (36%), Gaps = 48/275 (17%)
Query: 14 YPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQ 73
+ PPP PP P ASP S++ AP S LQ
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS-----------LAAPPLQVPPSPPAS 713
Query: 74 CVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRD 133
+ P PPP PPP P PP PP PP P+ +
Sbjct: 714 PPMSPSATPPPQAPPPLAAPPLQV----PPSPPASPPMSPSAT----------------- 752
Query: 134 GPPGLVPMELESPP-ESPPVPPGSYMPPSQSYMPPPQPPPSY-YPPTSSQPYLPPAQP-- 189
PP VP L +PP + PP PP S +P S PPPQ PP+ PP + P P + P
Sbjct: 753 -PPPRVPPLLAAPPLQVPPSPPAS-LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810
Query: 190 ---SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKS---- 242
SPS S P P P ++ + S P+ QA P+ G S
Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 870
Query: 243 ---QLLAPPPPSAPPGNKTTVQQEPLESGAKNKST 274
LAP PP P + ++ P +G + +T
Sbjct: 871 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 905
Score = 79.7 bits (195), Expect = 3e-14
Identities = 110/413 (26%), Positives = 141/413 (34%), Gaps = 71/413 (17%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSS-SGFMSFREQHLAQLQQLQQMHQKQMQC 74
PP + PP+ +P + P + +P A SS S L M +Q Q
Sbjct: 380 PPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQA 439
Query: 75 VL----QPHHLPP--PPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKH--Q 126
L +P PP PPL P +P PP+ PA+S H Q
Sbjct: 440 SLTSPSRPASTPPDSPPLQAPLSLPAS---------PPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 127 MLHHQRDGPPGLVPMELESPP---ESPPVPPGSYMPPSQSYMPPPQPPPSYYPP---TSS 180
L P L PP +S PP PP+ PP + PS PP T+S
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550
Query: 181 QPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS 240
P P +P P P+P ++ + S ++ P + ASP P QG
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSP-LTTPPPETPSSIATPPPQAPPALASP--PLQGLP 607
Query: 241 KSQL--LAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWY 298
L LA PPP APP Q P A+P P TP Q
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAP----------PSPPASPPLSPLA-TPSPQAPNAL 656
Query: 299 RQHLLSLQQRTKVHLPGHKKGPVVAKDTPE---PVKEEVTVPATS---------QVPESP 346
HLL + PV A +P PV T P+ + QVP SP
Sbjct: 657 AVHLL------QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 347 SSEEP-------------PLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAA 386
+ P PL P +VPP P P S R+ L AA
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
Score = 75.5 bits (184), Expect = 5e-13
Identities = 98/392 (25%), Positives = 137/392 (34%), Gaps = 62/392 (15%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
PP P P++LP + P +S +PA S ++ LQ L + Q
Sbjct: 451 PPDSPPLQAPLSLPASPP---LQTSLSPAVSPLSSPLTIHP-----LQALSSLASHSPQA 502
Query: 75 VLQPHHLPP----PPLPPPPVMPGGGYGDWQPPPPPMPPPPG---PALSYQKQQQYKHQM 127
L +PP L PP + Q PP + PP P+L+ Q +
Sbjct: 503 PLSSLIMPPLETQSSLAPPSL---------QTPPASLTTPPLENLPSLAPPPLQTASAPL 553
Query: 128 LHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYY------------ 175
+ PP P L++PP PP PS PPPQ PP+
Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPE--TPSSIATPPPQAPPALASPPLQGLPSPPL 611
Query: 176 -----PPTSSQPYL--PPAQ--PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLP 226
PP + P L PP Q PSP SPP P+P ++ + S P
Sbjct: 612 SPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
Query: 227 SSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPS 286
QA S P+ A PP APP Q P A + P+ P
Sbjct: 672 PVQAPFSPPASPPVSPS--ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Query: 287 TMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESP 346
P Q + + P + P++A P++ + PA+ +P SP
Sbjct: 730 LAAPPLQVP----PSPPASPPMSPSATPPPRVPPLLAAP---PLQVPPSPPAS--LPMSP 780
Query: 347 SSEEPPLPPPNEEVPP----PLPPEEPQSEDP 374
++ PP PP PP P PP + P
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAP 812
Score = 71.2 bits (173), Expect = 1e-11
Identities = 71/246 (28%), Positives = 90/246 (36%), Gaps = 31/246 (12%)
Query: 511 MGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLP------PPVMPPALPATVPPPGMPPPV 564
M ++ PPP P + PPL +P P P S P P P P PPP PP +
Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSP--PASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
Query: 565 MPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLP----PPSLSSTAPPPVMP 620
P L PP P + PP P P S +GP L PP S +P +
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 893
Query: 621 LPPL----SSATPPP-------GIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPR-- 667
P L SSAT P P G PP A PA+ S+ P R
Sbjct: 894 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 953
Query: 668 -PALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSS---FSSDQGLGES 723
A LP P + G ++ GP + L P +S ++ G G S
Sbjct: 954 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 1013
Query: 724 SAAPSQ 729
S +P Q
Sbjct: 1014 SRSPKQ 1019
Score = 64.3 bits (155), Expect = 1e-09
Identities = 84/307 (27%), Positives = 108/307 (35%), Gaps = 66/307 (21%)
Query: 15 PPPPVPPP---PPVALPEASPG-PGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQK 70
PPP PPP PP+ +P + P P S S TP R L LQ
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP---------RVPPLLAAPPLQVPPSP 772
Query: 71 QMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHH 130
+ P PPP PP P P+ P P S+ Q +
Sbjct: 773 PASLPMSPLAKPPPQAPPALATP------------PLQALPSPPASFPGQAPFS------ 814
Query: 131 QRDGPPGLVPME--LESPPESPPV--------PPGSYMPPSQSYMPPPQPPPSYYPPTS- 179
P +PM PP++PPV PP PP+ + P+ PP+ P TS
Sbjct: 815 ----PSASLPMSPLATPPPQAPPVLAAPLLQVPPS---PPASPTLQAPRRPPTPGPDTSV 867
Query: 180 SQPYL-----PPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSR 234
S P L P P PS+SP S +SSS++S+ L S P A+ S
Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG-PEGGAAASP 926
Query: 235 PSQG-----HSKSQLLAPPPPSAPPGNKTTVQQEPLESG---AKNKSTEQQQAAPE---P 283
P H + P PP A G P +G A T + PE P
Sbjct: 927 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 986
Query: 284 DPSTMTP 290
P + P
Sbjct: 987 APGALDP 993
Score = 58.2 bits (139), Expect = 9e-08
Identities = 99/425 (23%), Positives = 131/425 (30%), Gaps = 94/425 (22%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
P P P PP P S STT +P++ + + LQ+ + +
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA-------RRRPSAGGGLQRPASRSLSS 244
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134
P P P P P P P P G Q Q+ ++D
Sbjct: 245 SATPLSSPARSGPSARGTPRA------PAHPSQPKPKG------LQALRPPQVTPPRKDA 292
Query: 135 PPGLVPMELESPPESPPVPPGSYM----PPSQSYMP-----PPQPPPS----YYPPTSSQ 181
P L P L S P + P P G+ PP + P PP PP + PP+ S
Sbjct: 293 APALGP--LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA 350
Query: 182 PYLPPAQPSPSQSPPSQ------------------------------------------- 198
P PSP +PPSQ
Sbjct: 351 PPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
Query: 199 SYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPP---PPSAPPG 255
S A T S + ++ S+L+ S +S SPSRP+ S L P P S P
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQ 470
Query: 256 NKTTVQQEPLESGAKNKSTEQQQAAPEPDPST------MTPQEQQQYWYRQHL----LSL 305
+ PL S + + P M P E Q L SL
Sbjct: 471 TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530
Query: 306 QQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATS----QVPESPSSEEPPLPPPNEEVP 361
+LP P+ P T P + Q P SP + PP P + P
Sbjct: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590
Query: 362 PPLPP 366
PP P
Sbjct: 591 PPQAP 595
Score = 55.5 bits (132), Expect = 6e-07
Identities = 47/152 (30%), Positives = 61/152 (40%), Gaps = 38/152 (25%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPP----PPMGKPPGSIVRPSAPPARSSVPVTRPPVP 1545
PP +Q S P P S PP P + PP + P +PPA S P++ P
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--PPSPPA--SPPMS--PSA 720
Query: 1546 IPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPS- 1604
PPP PPPL PP + P A S S +A P
Sbjct: 721 TPPPQAPPPLAAPPLQVPPSPPA------------------------SPPMSPSATPPPR 756
Query: 1605 -APVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
P+L PP+ +PP P + M P++KPPP
Sbjct: 757 VPPLLAAPPL--QVPPSPPASLPMSPLAKPPP 786
Score = 54.7 bits (130), Expect = 1e-06
Identities = 62/230 (26%), Positives = 84/230 (36%), Gaps = 41/230 (17%)
Query: 1481 SEPQMADHLPPQESRLQNTSSRPGMYPP----PGSYRPPPPMGKPPGSIVRPSA-PPARS 1535
S P A PP + +++ P PP P PP P PP S PSA PP ++
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS---PSATPPPQA 726
Query: 1536 SVPVTRPPVPIPPPPPP---------PP-------------LPPPPPVIKPQTSAVEQER 1573
P+ PP+ +PP PP PP +PP PP P + +
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 1574 WDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAP--VLPPPPVHSSIPPPGPVPMGMPPMS 1631
+ T Q L S S P +P LP P+ ++ PP P + P +
Sbjct: 787 QAPPAL----ATPPLQALPSPPASFPGQAPFSPSASLPMSPL-ATPPPQAPPVLAAPLLQ 841
Query: 1632 KPPPVQQTVDYGHGRDISTNKVEQIPYGERITLR----PDPLPERSTFET 1677
PP + R T + G R+TL P P P RS T
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
Score = 54.3 bits (129), Expect = 1e-06
Identities = 40/143 (27%), Positives = 51/143 (35%), Gaps = 18/143 (12%)
Query: 1496 LQNTSSRPGMYPP----PGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPP 1551
L ++ P PP P PP P PP S + +P A +++ V P PPP
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 670
Query: 1552 PPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPP 1611
PP P P P S T Q S PS P PP
Sbjct: 671 PPVQAPFSPPASPPVSPSA--------------TPPSQAPPSLAAPPLQVPPSPPASPPM 716
Query: 1612 PVHSSIPPPGPVPMGMPPMSKPP 1634
++ PP P P+ PP+ PP
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPP 739
Score = 52.0 bits (123), Expect = 6e-06
Identities = 45/146 (30%), Positives = 55/146 (37%), Gaps = 28/146 (19%)
Query: 1508 PPGSYRPPPPMGKPPGSIVRP--SAPPARSSVPVTRPPVP------IPPPPPPPPL---- 1555
PP PPP + P SI P APPA +S P+ P P PPP PP L
Sbjct: 572 PPSPLTTPPP--ETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629
Query: 1556 ---PPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPP-- 1610
PP PP P + ++ L + F + AP PP
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNAL-------AVHLLQAPFSPPPSPPVQAPFSPPAS 682
Query: 1611 PPVHSSIPPPGPVP--MGMPPMSKPP 1634
PPV S PP P + PP+ PP
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPP 708
Score = 49.7 bits (117), Expect = 3e-05
Identities = 42/147 (28%), Positives = 50/147 (34%), Gaps = 39/147 (26%)
Query: 1501 SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPV-----PIPPP-----P 1550
+ P P G PP PP P+ P SS T P P+PPP P
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATP 326
Query: 1551 PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPP 1610
P LPP PP+ P A +A PS LP
Sbjct: 327 LPATLPPSPPLATPLPLA---------------------------PPSPSAPPSLQTLPS 359
Query: 1611 PPVHSSIPPPGPVPMGMPPMSKPPPVQ 1637
PP ++ P P M PPM PP +Q
Sbjct: 360 PP--ATPPSQAPPSMTTPPMQAPPSLQ 384
Score = 49.7 bits (117), Expect = 3e-05
Identities = 43/163 (26%), Positives = 63/163 (38%), Gaps = 37/163 (22%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPP----------PMGKPPGSIVRP--SAPPARSS 1536
+PP E+ Q++ + P + PP S PP P+ + P PP +
Sbjct: 509 MPPLET--QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAP 566
Query: 1537 VPVTRPPVPI--PPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSE 1594
P+ PP P+ PPP P + PPP P ++ QGL S
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL-----------------QGLPSP 609
Query: 1595 FKSETAAIP--SAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
S A P + P L PP+ + PP P+ P++ P P
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS--PLATPSP 650
Score = 45.1 bits (105), Expect = 8e-04
Identities = 104/428 (24%), Positives = 146/428 (34%), Gaps = 79/428 (18%)
Query: 522 PYSQMPPPLPTMPPPVLPPSLPPPVMPPALP--ATVPPPGMPP------PVMPPSLPTSV 573
P ++ P L PP P PPPV P AL G P + ++P S
Sbjct: 17 PAARAPGLLTPRPPG--SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74
Query: 574 PPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGI 633
P G S ++ P PP ++G PP +T+P PV S T P +
Sbjct: 75 PRAGPTRSAGTSSRNPASRPP---ASGRGERAPP--AKNTSPGPVSSPGRASGTTRPGPL 129
Query: 634 PPPG--------VPQGIPPQLTAAPVPPASSS-----QSSQVPEKPRPALLPTPVSFGS- 679
G V +G + T AP A S+ S P P PA+ + G+
Sbjct: 130 GQKGLRISAEETVARG---KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 680 ------APPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITA 733
AP PP + GP + V+S S + ++P A
Sbjct: 187 VGLPRPAPSARPRPPTE--GPRKSVSS---------------------ASEHSTTEPSPA 223
Query: 734 VKDMPVRSGGLLPDPPRS-----SYLESP--RGPRFDGPRRFEDLGSRCEGPRPKGPRFE 786
+ P GGL RS + L SP GP G R S+ P+PKG +
Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ---PKPKGLQ-A 279
Query: 787 GNRPDGPRPRYEGHPAEGTKSKWGMI---PRGPASQFYITPSTSLSPRQSGPQWKGPKPA 843
P PR + PA G S + P G ++ P + +P P P P
Sbjct: 280 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL---PATLPPSPP 336
Query: 844 FGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENL- 902
P S + P S P + Q M + ++ + Q +L
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396
Query: 903 SDSQQEPP 910
S S Q PP
Sbjct: 397 SPSLQAPP 404
Score = 38.1 bits (87), Expect = 0.094
Identities = 47/210 (22%), Positives = 75/210 (35%), Gaps = 36/210 (17%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPG-----SYRPPPPMGKPPGSIVRP--SAPPARS 1535
P +PP + + ++ + P + PP S + +G P + P ++
Sbjct: 380 PPSLQTIPPIQ--VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT 437
Query: 1536 SVPVTRPPVPIPPPPPPPPLPPP------PPVIKPQTSAVEQERWDEDSFYGLWDTNDEQ 1589
+T P P PP PPL P PP+ + AV + Q
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP-------LSSPLTIHPLQ 490
Query: 1590 GLNSEFKSETAAIPSAPVLPPPPVHSSIPPPG----PVPMGMPPMSK-----PPPVQQTV 1640
L+S A S+ ++PP SS+ PP P + PP+ PPP+Q
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTA- 549
Query: 1641 DYGHGRDISTNKVEQIPYGERITLRPDPLP 1670
++T +E P L+ P P
Sbjct: 550 ----SAPLTTPHLETPPCPAPCPLQAPPSP 575
Score = 34.7 bits (78), Expect = 1.0
Identities = 34/145 (23%), Positives = 54/145 (37%), Gaps = 7/145 (4%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP 1549
PP S + + P P S + PP M PP APP+ ++P + P + P
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPS-QAPPSMTTPP-----MQAPPSLQTIPPIQVPHSLTSP 398
Query: 1550 P-PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVL 1608
PP P ++ TS SF + + L S + + S P+
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
Query: 1609 PPPPVHSSIPPPGPVPMGMPPMSKP 1633
P + +S P + + P+S P
Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSSP 483
Score = 33.9 bits (76), Expect = 1.8
Identities = 38/127 (29%), Positives = 48/127 (37%), Gaps = 19/127 (14%)
Query: 1066 EDSREKMNRGEGSRDR-----GLVRP---GSSREKVPGGLQGSQDRGAAGSRERGP-PRR 1116
++ R+K G +R GL+ P GS R P + GAAG+ R P R
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
Query: 1117 AG----------SQERGPLRRAGSRERIPPRRAGSRERGPPRGPGSRERGLGRSDFGRDR 1166
AG + GP R AG+ R P R + RG P S GR
Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
Query: 1167 GPFRPEP 1173
G RP P
Sbjct: 122 GTTRPGP 128
Score = 32.3 bits (72), Expect = 5.1
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 32/89 (35%)
Query: 1508 PPGSYRPPPP--------------MGKPP---------GSIVRPSAP---PARSSVPVTR 1541
PPGS RPPPP +G+ P G+ + SAP P RS+ +R
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 1542 PPVPIPPP------PPPPPLPPPPPVIKP 1564
P PP PP P PV P
Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVSSP 117
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 115 bits (289), Expect = 4e-25
Identities = 192/920 (20%), Positives = 328/920 (35%), Gaps = 187/920 (20%)
Query: 18 PVPPP-----PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
PVP P PP +PE P AP E A++ ++ +
Sbjct: 10018 PVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKV------EAPPAKVPEVPKK----- 10066
Query: 73 QCVLQPHHLPPPPLP-----PPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQM 127
L P P P+P PPP +P +P P P+ P + ++++ + ++
Sbjct: 10067 ---LIPEEKKPTPVPKKVEAPPPKVPKKR----EPVPVPVALPQEEEVLFEEEIVPEEEV 10119
Query: 128 LHHQRDGPPG---LVPMELESPPESPPVPPGSY-MPPSQSYMPPPQPPPSYYPPTSSQPY 183
L + + P ++P E E PE +PP +PP + Y+P + + P P
Sbjct: 10120 LPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEE---EFVPEEEVLPE 10176
Query: 184 LPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243
+ P P P AP P + + + + P+ P P + K
Sbjct: 10177 VKPKVPVP----------APVPEIKKKVTEKKVVIPKKEEAPPAKV--PEVPKKVEEKRI 10224
Query: 244 LLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLL 303
+L P ++EP+ ++ PE PS +
Sbjct: 10225 ILPKEEEVLPVEVTEEPEEEPIS----------EEEIPEEPPS---------------IE 10259
Query: 304 SLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQ-VPESPSSEEPPLPPPNEEVPP 362
+++ +P K V TP P K E S+ +PE E+ P+P +E PP
Sbjct: 10260 EVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE----EKVPVPVQKKEAPP 10315
Query: 363 PLPPEEPQSEDPEEDARLKQLQA---AAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQY 419
PE P+ PE+ + + +A A ++ V F+ + ++++ +L+ + +
Sbjct: 10316 AKVPEVPKKV-PEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEV 10374
Query: 420 QQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWER-EFQLWEEQLHSYPHKDQLQEY 478
++I ++++F + + +E EF EE + H+
Sbjct: 10375 EEI--------------------PEEEEFHEVEEYFEEGEFHEVEEFIKLEQHR-----V 10409
Query: 479 EKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMG----NMSMPPPFVPYSQMP------- 527
E++ + + H + + + E+V F+ K G +PP P +P
Sbjct: 10410 EEEHRVEKVH-RVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAK 10468
Query: 528 ----------------PPLPTMPPPVLPPSLPPPVMPPALPATVPP---PGMPPPVMP-- 566
P P +PP +P LPP + P VPP P PPP +P
Sbjct: 10469 VPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEA 10528
Query: 567 -----PSLPTSVPPPG---MPPSLSSAGPPPVLPPPSLSSAGPP-PVLPPPSLSSTAPPP 617
P VPPP +PP+ P +P + A PP P PPP + AP
Sbjct: 10529 PKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPE-APKE 10587
Query: 618 VMPLPPLSSATPP-PGIPPPGVPQG----IPPQLTAAPVPPASSSQSSQVPEKPR----- 667
V+P + +A P P + P VP+ +P + P P ++VPE P+
Sbjct: 10588 VVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPE 10647
Query: 668 ---PALLPTPVSFGSAPPTTYHPPLQSA---GPSEQVNS---KAPLSKSALPYSSFSSDQ 718
P +P S PP + P + A P+E V AP + P +
Sbjct: 10648 KKVPEAIPPKPE--SPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKK 10705
Query: 719 GLGESSAAPSQPITAVKDMP------VRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLG 772
+ P P V ++P + ++P P + + P P+ P + +
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765
Query: 773 SRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQ 832
+ E P K P +P E PA + P + Y P +
Sbjct: 10766 KKPEVPPAKVPEVP------KKPVLEEKPAVPVPER----AESPPPEVYEEPEEIAPEEE 10815
Query: 833 SGPQWKGPKPAFGQQHQQQP 852
P+ + P P ++ + P
Sbjct: 10816 IAPEEEKPVPVAEEEEPEVP 10835
Score = 78.2 bits (191), Expect = 8e-14
Identities = 177/870 (20%), Positives = 299/870 (34%), Gaps = 163/870 (18%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
PPP VP P PE P AP + ++ + +K+
Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPIPKKVEPPAPK-----------VPEVPKKPVPEEKKPVP 9332
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ--QQYKHQMLHHQR 132
V + PP +P P P P PP QK + K ++ +
Sbjct: 9333 VPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQRE 9392
Query: 133 DGPPGLVPM--ELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPS 190
+ PP VP + + P E PVP P PPP+ P P + P P
Sbjct: 9393 ESPPPAVPEIPKKKVPEERKPVPRKEEEVP-----PPPKVPALPKKPVPEEKVAVPV-PV 9446
Query: 191 PSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPP 250
++PP ++ ++ ++ LS A P R +
Sbjct: 9447 AKKAPPPRAEVSKKTVVEEKRFVAEEKLSF---------AVPQRVEVTRHEV-------- 9489
Query: 251 SAPPGNKTTVQQEPLE-SGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRT 309
SA + ++E + S + + E+++ A + M E+ + H++S +
Sbjct: 9490 SAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEA 9549
Query: 310 KVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP----PLP-PPNEEVPPPL 364
+ ++ + P K E PA +VPE+P P P P P E+VPPP
Sbjct: 9550 EPAEVTERQEKKIVLKPKIPAKIEEPPPA--KVPEAPKKIVPEKKVPAPVPKKEKVPPPK 9607
Query: 365 PPEEPQSEDPEEDARLKQLQ--------AAAAHWQQHQQHRV-----------GFQYQGI 405
PEEP+ PE+ K ++ H Q Q+ +V +
Sbjct: 9608 VPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEE 9667
Query: 406 MQKHTQLQQILQQYQQIIQPPPH---------IQTMSVDMQLRHYEMQQQQFQHLYQEWE 456
++ +++L+ + + PP ++ V ++ E Q + + +E E
Sbjct: 9668 PKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKE 9727
Query: 457 REFQLWEEQLHSYPHKDQLQEYEK-QWKTWQGHMKATQSYLQ-----EKVNSFQNMKNQY 510
R + L EE+ S +++ +EYE+ +K ++ + + T+ Y Q E+ +Y
Sbjct: 9728 RAYTL-EEEAVSVQREEEYEEYEEYDYKEFEEY-EPTEEYDQYEEYEEREYERYEEHEEY 9785
Query: 511 MGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPA-----LPATVPPPGMPPPVM 565
+ P P P+P P P P + P V+ A +P +P PPP
Sbjct: 9786 ITEPEKPIPV-------KPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPK 9838
Query: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLP----PPSLSSTAPPPVMPL 621
P P V + S++ V P + P V+ P APP +P
Sbjct: 9839 VPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPE 9898
Query: 622 PP------------------------------------LSSATPPPGIP--PPGVP-QGI 642
P ++ P IP P VP + +
Sbjct: 9899 VPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPV 9958
Query: 643 PPQLTAAPVPPASSSQSSQVPEKPR------PALLPTPVSFGSAPPTTYHPPLQSAGPSE 696
P + PVP + ++VPE P+ P L+P PP + P E
Sbjct: 9959 PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK---EKPPPAKVPEVPKKPVPEE 10015
Query: 697 QVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLES 756
+V P A P + P +P+ K +PV + + PP +
Sbjct: 10016 KVPVPVPKKVEAPP----------AKVPEVPKKPVPE-KKVPVPAPKKVEAPP----AKV 10060
Query: 757 PRGPR--FDGPRRFEDLGSRCEGPRPKGPR 784
P P+ ++ + + E P PK P+
Sbjct: 10061 PEVPKKLIPEEKKPTPVPKKVEAPPPKVPK 10090
Score = 77.0 bits (188), Expect = 2e-13
Identities = 113/588 (19%), Positives = 211/588 (35%), Gaps = 105/588 (17%)
Query: 139 VPMELESPPESP-PVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLP--PAQPSPSQSP 195
+P ++E PP + P P +P + +P P P PP P +P P +P P +
Sbjct: 9568 IPAKIEEPPPAKVPEAPKKIVPEKK--VPAPVPKKEKVPP----PKVPEEPKKPVPEKKV 9621
Query: 196 PSQSYLAPTP-------SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLA-- 246
P + P + + + ++ ++ P P P + + ++L
Sbjct: 9622 PPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLK 9681
Query: 247 PPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPS-TMTPQEQQQYWYRQHLLSL 305
P PP T ++ ++ + S E + P+P T+ ++++ Y + +S+
Sbjct: 9682 PKREEEPPAKVTEFRKRVVKE--EKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSV 9739
Query: 306 QQRTKV-------HLPGHKKGPVVAKDTPEPVKEE-----------VTVPA----TSQVP 343
Q+ + + + P D E +E +T P VP
Sbjct: 9740 QREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVP 9799
Query: 344 ESPSSEEPPLPP--------PNEEVPPPLPPE--EPQSEDPEEDARL--KQLQAAAAHWQ 391
E P +P PP P E+VP P+P + P + PEE ++ ++++ + +
Sbjct: 9800 EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKRE 9859
Query: 392 QHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHL 451
+ Q + + K ++ + ++ + PP + + +++ +++ H+
Sbjct: 9860 KEQVTEPAAKVP-MKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHV 9918
Query: 452 YQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYM 511
E+ + EE+ + + ++ + E E
Sbjct: 9919 -----EEYLVEEEEEYIHEEEEFITEEEVV------------------------------ 9943
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPP-PGMPPPVMPPSLP 570
P +P P +P P P +P P A PA VP P P +P +P
Sbjct: 9944 -------PVIPVKV--PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIP 9994
Query: 571 TSV-PPPGMPPSLSSAG-PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSAT 628
PPP P + P +P P PP P P +P+P
Sbjct: 9995 KKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVE 10054
Query: 629 PPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVS 676
PP P + IP + PVP + +VP+K P +P PV+
Sbjct: 10055 APPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREP--VPVPVA 10100
Score = 70.1 bits (170), Expect = 2e-11
Identities = 85/390 (21%), Positives = 134/390 (34%), Gaps = 47/390 (12%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
PP P PP +PEA P P P E ++ ++ + + +
Sbjct: 10513 PPAKKPEAPPPKVPEA-PKEVVPEKKVPVPPPKKP-----EVPPTKVPEVPKAAVPEKKV 10566
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134
P +PP P PPP +P P PP P ++ K + +++ ++
Sbjct: 10567 ---PEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVP 10623
Query: 135 PPGLVPMELESPPESPPVPPGSYMPPS---QSYMPPPQPPPS--YYPPTSSQPYLPPAQP 189
P P + E PP P P +P ++ P P+ PP + P PPA+
Sbjct: 10624 VPP--PKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEV 10681
Query: 190 SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPP 249
P + + P + + ++ P + K L+ P
Sbjct: 10682 VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKK 10741
Query: 250 PSAPPGN------------KTTVQQEPLESGAKNKST------EQQQAAPEPDPSTMTPQ 291
P APP K V ++P AK E++ A P P+ + P
Sbjct: 10742 PEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPP 10801
Query: 292 EQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP 351
E + + + P + P K P +EE VP + VPE P P
Sbjct: 10802 E------------VYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPA-VPEEPKKIIP 10848
Query: 352 PLPPPNEEVPPPLPPEEPQSEDPEEDARLK 381
P + P PP+EP+ E E +LK
Sbjct: 10849 EKKVPVIKKPEAPPPKEPEPEKVIEKPKLK 10878
Score = 67.0 bits (162), Expect = 2e-10
Identities = 100/434 (23%), Positives = 149/434 (34%), Gaps = 107/434 (24%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
PP VP P VA+PE P P S F E L++ +
Sbjct: 10633 PPTKVPEVPKVAVPEKKV-----PEAIPPKPESPPPEVFEEPEEVALEE------PPAEV 10681
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPP-----PPMPPPPGPALSYQKQQQYKHQMLH 129
V +P PP + PP P + + P P +PP P + + + K
Sbjct: 10682 VEEPEPAAPPQVTVPPKKP---VPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKK----- 10733
Query: 130 HQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPP-PQPPPSYYPPTSSQPYLP--P 186
P +VP + E+PP P P +P + +P P+ PP+ P +P L P
Sbjct: 10734 -----VPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKP 10788
Query: 187 AQPSP--SQSPPSQSY-----LAPTPSYSSSSSSSQSYLSHSQSYLP------------- 226
A P P ++SPP + Y +AP + + +P
Sbjct: 10789 AVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIP 10848
Query: 227 --------SSQASPSR---PSQGHSKSQLLA--PPPPSAPPGNKTTVQQEPLESGAKNKS 273
+A P + P + K +L PPPP APP + L++ K K
Sbjct: 10849 EKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKV 10908
Query: 274 TEQQQAA-------------------------PEPDPSTMT-------PQEQQQYWYRQH 301
E+ Q PEP + P+E++ +
Sbjct: 10909 PEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKK 10968
Query: 302 LLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPE----SPSSEEPPLPPPN 357
L +++ P K PV + P K E +P ++VPE P P P P
Sbjct: 10969 LEKVKKPAVPEPPPPK--PVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPE 11026
Query: 358 EEV----PPPLPPE 367
EV PPP+ PE
Sbjct: 11027 AEVKTIKPPPVEPE 11040
Score = 65.9 bits (159), Expect = 4e-10
Identities = 113/558 (20%), Positives = 197/558 (35%), Gaps = 76/558 (13%)
Query: 165 MPPPQPPPSYYP-PTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQS 223
+ PP P S P PT +PP + P +PP L PTP + ++
Sbjct: 8932 LKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPI-PLLLPTP--EEKKPPPKRIEVTKKA 8988
Query: 224 YLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEP 283
++ ++P + + +++ PPP T + + E + E+ +
Sbjct: 8989 VKKDAKKVVAKPKEMTPREEIVKKPPPPT-----TLIPAKAPEIIDVSSKAEEVKIMTIT 9043
Query: 284 DPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVP 343
+ +++ Y +Q + HK+ V + EP E P T
Sbjct: 9044 RKKEVQKEKEAVYEKKQAV-------------HKEKRVFIESFEEPYDELEVEPYTEPF- 9089
Query: 344 ESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEED----ARLKQLQAAAAHWQQHQQHRVG 399
E P EEP +V E ED EE R + W++ Q R
Sbjct: 9090 EQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREV 9149
Query: 400 FQYQGIMQKHTQLQQILQQY-QQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWERE 458
Q Q + + + +++ + ++ PPP + V + E ++ + + +
Sbjct: 9150 IQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPV---IEKIEKTSRRMEEEKVQVTKV 9206
Query: 459 FQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKAT---------QSYLQEKVN-SFQNMKN 508
++ ++ + P + +QE + K H K S+ +E+V+ + ++
Sbjct: 9207 PEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQK 9266
Query: 509 QYMGNMSM---------PPPFVPYSQMPPPLPTMPPP--VLPPSLPPPVMPPALPATVPP 557
+ + + PPP V P LP P P V P +P V PPA P
Sbjct: 9267 EIVTEEKIHVAISKRVEPPPKV------PELPEKPAPEEVAPVPIPKKVEPPA-PKVPEV 9319
Query: 558 PGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPV----LPPPSLSSAGPPPVLPPPSLSST 613
P P P +P P PP + PV +P P PP P
Sbjct: 9320 PKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGV 9379
Query: 614 APPPVMPLPPLSSATPPPGIPP------PGVPQGIPPQLTAAPVPPASSSQSSQVPEKPR 667
+ + +PPP +P P + +P + P PP + +P+KP
Sbjct: 9380 VTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPP----KVPALPKKPV 9435
Query: 668 P---ALLPTPVSFGSAPP 682
P +P PV+ + PP
Sbjct: 9436 PEEKVAVPVPVAKKAPPP 9453
Score = 64.3 bits (155), Expect = 1e-09
Identities = 84/416 (20%), Positives = 142/416 (34%), Gaps = 43/416 (10%)
Query: 516 MPPPFVPYSQMPPPLPTMP--PPVLPPSLPPPVMPPALPATVPPPGMPPPVMP--PSLPT 571
+P VP ++P +P P PP P +P V+P A P +PP +P P P
Sbjct: 10724 VPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPV 10783
Query: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPP 631
P +P + PPP + P + P ++ PV PPP
Sbjct: 10784 LEEKPAVPVPERAESPPPEVYEE------PEEIAPEEEIAPEEEKPVPVAEEEEPEVPPP 10837
Query: 632 GIPPPG---VPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPP------ 682
+P +P+ P + PP + +V EKP+ L P P APP
Sbjct: 10838 AVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPK--LKPRPPPPPPAPPKEDVKE 10895
Query: 683 ---TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPV 739
P + QV K L+ +P + L E P + + +
Sbjct: 10896 KIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRK 10955
Query: 740 RSGGLLP--DPPRSSYLESPRGPRFDGPRRFEDLG----SRCEGPRPKGPRFEGNRPDGP 793
R P +P + ++ P P P+ E++ ++ E P+ + +P P
Sbjct: 10956 RPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIP 11015
Query: 794 RPRYEGHPAEGTKSKWGMIP-----RGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQH 848
P E P + K P P + P P+ + KP
Sbjct: 11016 LPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPK--GPI 11073
Query: 849 QQQPKSQAEPLSGNKEPLADTSSNQQK------NFKMQSAAFSIAADVKDVKAAQS 898
+ PK P+ + L S ++ +++++ ++KD+ +S
Sbjct: 11074 KGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTES 11129
Score = 60.8 bits (146), Expect = 1e-08
Identities = 87/427 (20%), Positives = 154/427 (36%), Gaps = 62/427 (14%)
Query: 320 PVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEV--PPP----LPPEEPQSED 373
P + P P + EVT A + + ++ + P E V PPP +P + P+ D
Sbjct: 8970 PTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIID 9029
Query: 374 PEEDA-RLKQLQAAAAHWQQHQQHRVGFQYQGI-MQKHTQLQQILQQYQQIIQPP---PH 428
A +K + Q ++ V + Q + +K ++ + Y ++ P P
Sbjct: 9030 VSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPF 9089
Query: 429 IQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGH 488
Q + + E++ + + +++EWE +F EE Y ++ E E++W+
Sbjct: 9090 EQPYYEEPDEDYEEIKVEAKKEVHEEWEEDF---EEGQEYYEREEGYDEGEEEWE----- 9141
Query: 489 MKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVL---------- 538
++Y + +V Q + +P VP + PPP + PV+
Sbjct: 9142 ----EAYQEREVIQVQKEVYEESHERKVPAK-VPEKKAPPPPKVIKKPVIEKIEKTSRRM 9196
Query: 539 -PPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAG----------- 586
+ +P VP PV + VP + S
Sbjct: 9197 EEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEE 9256
Query: 587 --------PPPVLPPPSLSSAGPPPVLPPPSL----SSTAPPPVMPLPPLSSATPPPGIP 634
++ + A V PPP + AP V P+P PP
Sbjct: 9257 VSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKV 9316
Query: 635 PPGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRP-ALLPTPVSFGSAPPTTYHPPLQ 690
P + +P + PVP PA+ + +VP+KP P +P PV+ P P +Q
Sbjct: 9317 PEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQ 9376
Query: 691 SAGPSEQ 697
+E+
Sbjct: 9377 KGVVTEE 9383
Score = 54.7 bits (130), Expect = 1e-06
Identities = 97/505 (19%), Positives = 165/505 (32%), Gaps = 106/505 (20%)
Query: 139 VPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQ 198
+ +E PP+ P +P P+ + P P PP P + P +P P + P
Sbjct: 9278 ISKRVEPPPKVPELPE----KPAPEEVAPVPIPKKVEPPAPKVPEV-PKKPVPEEKKP-- 9330
Query: 199 SYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKT 258
P P ++ PP P K
Sbjct: 9331 ---VPVPKKEPAA-------------------------------------PPKVPEVPKK 9350
Query: 259 TVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKK 318
V +E + K PE +T +
Sbjct: 9351 PVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEE--------------------------- 9383
Query: 319 GPVVAKDTPEPVKEEVTVPATSQVPESPSSEE-PPLPPPNEEV-PPPLPPEEPQSEDPEE 376
K T +EE PA ++P+ EE P+P EEV PPP P P+ PEE
Sbjct: 9384 -----KITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEE 9438
Query: 377 DARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDM 436
+ A A + + + + +L + Q ++ + +S +
Sbjct: 9439 KVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTR-----HEVSAEE 9493
Query: 437 QLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEY--EKQWKTWQGHMKATQS 494
+ + E ++ +Y+E ERE + E ++ Y ++ +EY E++ ++A +
Sbjct: 9494 EWSYSEEEEGVSISVYREEERE-EEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPA 9552
Query: 495 YLQEKVNSFQNMKNQYMGNMSMPPP---------FVPYSQMPPPLPTMPPPVLPPSLPPP 545
+ E+ +K + + PPP VP ++P P+P +PPP
Sbjct: 9553 EVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPK------KEKVPPP 9606
Query: 546 VMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVL 605
+P VP +PP V+ P +P + VL + A P +
Sbjct: 9607 KVPEEPKKPVPEKKVPPKVIKMEEP--LPAKVTERHMQITQEEKVLVAVTKKEAPPKARV 9664
Query: 606 PPPSLSSTAPPPVMPLPPLSSATPP 630
P + V+ L P PP
Sbjct: 9665 PEEPKRAVPEEKVLKLKPKREEEPP 9689
Score = 47.4 bits (111), Expect = 2e-04
Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 15/103 (14%)
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPP--GMPPP-------- 563
+ + PP +P S++P +PTMP +PP PPV+ P +P +P P PPP
Sbjct: 8930 LELKPPDIPDSRVP--IPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKK 8987
Query: 564 -VMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVL 605
V + P M P PP PP +L A P ++
Sbjct: 8988 AVKKDAKKVVAKPKEMTPREEIVKKPP--PPTTLIPAKAPEII 9028
Score = 46.2 bits (108), Expect = 3e-04
Identities = 54/226 (23%), Positives = 80/226 (35%), Gaps = 60/226 (26%)
Query: 1508 PPGSYRPPPPMGKPPGSIVR----PSAPPARSSV-PVTRPPVP--------IPPPPPPPP 1554
PP PPP + + P +V P+APP + V PV P P +P PPP P
Sbjct: 10571 PPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKP 10630
Query: 1555 LPPP----------------PPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSE---- 1594
PP P I P+ + E ++E L + E E
Sbjct: 10631 EVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAP 10690
Query: 1595 ------------FKSETAAIPSAPVLPP---PPVHSSIPPPGPVPMGMPPMSKPPPV--- 1636
K A + P LPP P V + P VP+ +P + PP
Sbjct: 10691 PQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVP 10750
Query: 1637 --------QQTVDYGHGRDISTNKVEQIPYGERITLRPD-PLPERS 1673
++ V ++ KV ++P + +P P+PER+
Sbjct: 10751 EVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERA 10796
Score = 45.8 bits (107), Expect = 4e-04
Identities = 66/315 (20%), Positives = 106/315 (33%), Gaps = 33/315 (10%)
Query: 81 LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140
+PP +P P P P P PP ++ + ++ + P
Sbjct: 10770 VPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEE 10829
Query: 141 MELESPPESPPVPPGSYMPPSQSYM--PPPQPPPSYYPPTS--SQPYLPPAQPSPSQSPP 196
E E PP + P P +P + + P PPP P +P L P P P +PP
Sbjct: 10830 EEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPP 10889
Query: 197 SQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAP---PPPSAP 253
+ + + + + +P + G K + L P P P
Sbjct: 10890 KEDV---KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEE 10946
Query: 254 PGNKTTVQQEPLESGAK--NKSTEQQQAAPEPDPSTMTPQEQQQY-WYRQHLLSLQQRTK 310
K+ +++ P E K K E+ + P+P P E+ + + + + TK
Sbjct: 10947 VVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK 11006
Query: 311 VH---------LPGHKKGPVVAKDT---------PEPVKEEVTVPATSQVPESPSSEEPP 352
V P K P T P P+ VTVP + E+ + +E
Sbjct: 11007 VPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA 11066
Query: 353 LPP--PNEEVPPPLP 365
P P + VP P
Sbjct: 11067 AKPKGPIKGVPKKTP 11081
Score = 45.4 bits (106), Expect = 6e-04
Identities = 131/688 (19%), Positives = 236/688 (34%), Gaps = 136/688 (19%)
Query: 1269 ERDQDMDE-------DYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYG-----RPL 1316
E D+D +E + + E E D + + R + YD + EW+ Y +
Sbjct: 9096 EPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYERE-EGYDEG-EEEWEEAYQEREVIQVQ 9153
Query: 1317 DEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREY 1376
E + ER +P+ P PP P + + E+ +R + ++++ +
Sbjct: 9154 KEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRR-------MEEEKVQVTKV 9206
Query: 1377 PERGDTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMGSDASL 1436
PE + VP + PS + E + H+ +M+ S+ +
Sbjct: 9207 PE------VSKKIVPQK-------------PSRTPVQEEVIEVKVPAVHTKKMVISEEKM 9247
Query: 1437 DSDQGLGGVMVLSQRQHEIILKAAQELK-MLREQKEQLQKMKDFGSEPQMADHLPPQESR 1495
S + E+ + + K ++ E+K + K EP PP+
Sbjct: 9248 ---------FFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRV--EP------PPKVPE 9290
Query: 1496 LQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPL 1555
L + + P P + PP K P + + P + VPV + PP P P
Sbjct: 9291 LPEKPAPEEVAPVPIPKKVEPPAPKVP-EVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPK 9349
Query: 1556 PPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPP----- 1610
P P P A ++E E+ + + E + P+ P +P
Sbjct: 9350 KPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPE 9409
Query: 1611 -----PPVHSSIPPPGPVP-------------MGMPPMSKPPP----VQQTVDYGHGRDI 1648
P +PPP VP + +P K PP V + R +
Sbjct: 9410 ERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFV 9469
Query: 1649 STNKVE-QIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHR 1707
+ K+ +P +T E ++ E G RE +RE + + + ++
Sbjct: 9470 AEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEERE---EEEEAEVTEYE 9526
Query: 1708 DFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGFDRPSYD 1767
+ E V++ + ++KK +P
Sbjct: 9527 VMEEPEEY---------VVEEKLHIISKRVEAEPAEVTERQEKKI--------VLKPKIP 9569
Query: 1768 RKSDRP----VYEGPSMFGGERRTYPEERMPLPAPSLSHQPPP-APRVEKK--PESKNVD 1820
K + P V E P ++ PE+++P P P PPP P KK PE K
Sbjct: 9570 AKIEEPPPAKVPEAP------KKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPP 9623
Query: 1821 DILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRD--------KEVEFGGPAPRVLSLD 1872
++K E P ++ + K VA ++ +E + P +VL L
Sbjct: 9624 KVIKM--EEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKL- 9680
Query: 1873 DYFITEVEKEEKDPDSGKKVKKKVMEYE 1900
+ ++EE+ P + +K+V++ E
Sbjct: 9681 -----KPKREEEPPAKVTEFRKRVVKEE 9703
Score = 43.9 bits (102), Expect = 0.002
Identities = 86/410 (20%), Positives = 156/410 (38%), Gaps = 64/410 (15%)
Query: 1515 PPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP----PPPPPPLPPPPPV----IKPQT 1566
P + +PP + V P AP + VP + P P+P PPP P P PV + P+
Sbjct: 9569 PAKIEEPPPAKV-PEAP--KKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKV 9625
Query: 1567 SAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMG 1626
+E+ + + + T +E+ L + K E P P V P V
Sbjct: 9626 IKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAV-----PEEKVLKL 9680
Query: 1627 MPPMSKPPPVQQTVDYGHGRDISTNKVE-QIPYGERITLRPDPLPERSTFETEHAG---- 1681
P + PP + T R + KV + P E P P+ E + E +
Sbjct: 9681 KPKREEEPPAKVTEF--RKRVVKEEKVSIEAPKRE-----PQPIKEVTIMEEKERAYTLE 9733
Query: 1682 -QRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDR-DRFDRERRP 1739
+ RE + E Y + D+++F+ T +YD+ + ++
Sbjct: 9734 EEAVSVQREEEYEEYEEY------DYKEFEEYEPTE----------EYDQYEEYEEREYE 9777
Query: 1740 RDDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPS 1799
R + + Y + + + + P + P ++ PEE++P+P P
Sbjct: 9778 RYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKV-------LKKAVPEEKVPVPIP- 9829
Query: 1800 LSHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEV 1859
PP P+V ++P+ K ++ ++ + E++ +P K +++ +++V
Sbjct: 9830 -KKLKPPPPKVPEEPK-KVFEEKIRISITKREKEQVTEPAAKVPMKPK----RVVAEEKV 9883
Query: 1860 EFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETY 1909
P PR + EV KE + + + + EY E EE Y
Sbjct: 9884 ----PVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEY 9929
Score = 43.1 bits (100), Expect = 0.003
Identities = 81/451 (17%), Positives = 156/451 (34%), Gaps = 62/451 (13%)
Query: 1465 MLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGS 1524
++ E++E + + ++F +E ++ +P + P +P P KP
Sbjct: 9922 LVEEEEEYIHEEEEFITEEEVVPVIPVKV--------------PEVPRKPVPEEKKPVPV 9967
Query: 1525 IVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWD 1584
+ APPA+ +P +P P PPP V + V +E+
Sbjct: 9968 PKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP------- 10020
Query: 1585 TNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGH 1644
+ + ++ A +P P P P +P P P + PP P ++ +
Sbjct: 10021 ------VPKKVEAPPAKVPEVPKKPVP--EKKVPVPAPKKVEAPPAKVPEVPKKLIPEEK 10072
Query: 1645 GRDISTNKVEQIPYGERITLRPDPLP------ERSTFETEHAGQRDRYDRER----DREP 1694
KVE P P P+P E FE E + + E + E
Sbjct: 10073 KPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEE 10132
Query: 1695 YFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRER-----RPRDDRAQSYRD 1749
+ V+ + + + E + + + + + E +P+ +
Sbjct: 10133 VLPEEEEVLPEEEEIPPEEE---EVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPE 10189
Query: 1750 KKDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAPSLSHQPPPAPR 1809
K + ++ P + V E P +R P+E LP ++ +P P
Sbjct: 10190 IKKKVTEKKVVI--PKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPV-EVTEEPEEEPI 10246
Query: 1810 VEKK--PESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPR 1867
E++ E +++++ E P R+ +++ T V K + + P
Sbjct: 10247 SEEEIPEEPPSIEEV-----EEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIP- 10300
Query: 1868 VLSLDDYFITEVEKEEKDPDSGKKVKKKVME 1898
++ V+K+E P +V KKV E
Sbjct: 10301 ----EEKVPVPVQKKEAPPAKVPEVPKKVPE 10327
Score = 42.7 bits (99), Expect = 0.004
Identities = 49/188 (26%), Positives = 68/188 (36%), Gaps = 40/188 (21%)
Query: 1491 PQESRLQNTSSRPGMYPP----PGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPI 1546
P+E R+ T P + PP P P PP KP P P A V P +
Sbjct: 10485 PEEPRVPPTKV-PEVLPPKEVVPEKKVPVPPAKKPEAP--PPKVPEAPKEVV---PEKKV 10538
Query: 1547 PPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAP 1606
P PPP P PP V + +AV +++ E AIP P
Sbjct: 10539 PVPPPKKPEVPPTKVPEVPKAAVPEKKVPE------------------------AIPPKP 10574
Query: 1607 VLPPPPVHSS---IPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERIT 1663
PPP V + + P VP P K P V +++ K +P ++
Sbjct: 10575 ESPPPEVPEAPKEVVPEKKVPAAPP---KKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631
Query: 1664 LRPDPLPE 1671
+ P +PE
Sbjct: 10632 VPPTKVPE 10639
Score = 41.2 bits (95), Expect = 0.011
Identities = 75/345 (21%), Positives = 122/345 (35%), Gaps = 87/345 (25%)
Query: 1514 PPPPMGKPPGSIVRPSAPPAR---SSVPVTRPPVPIPP--PPPPPPLPPPPPVI---KPQ 1565
P P+ + P +P APPA+ +VP + PVPIP PPPP +P P + K +
Sbjct: 9794 PVKPVPEEPVP-TKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIR 9852
Query: 1566 TSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPM 1625
S ++E+ E +E AA P+ P V P
Sbjct: 9853 ISITKREK--------------------EQVTEPAA--KVPMKPKRVVAEEKVP------ 9884
Query: 1626 GMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDR 1685
+P PPV +V ++P + PE FE E +
Sbjct: 9885 -VPRKEVAPPV---------------RVPEVP--------KELEPEEVAFEEEVVTHVEE 9920
Query: 1686 YDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPRDDRAQ 1745
Y E + E I + +F + E VI R+ P + +
Sbjct: 9921 YLVEEEEE--------YIHEEEEFITEEEV-------VPVIPVKVPEVPRKPVPEEKKPV 9965
Query: 1746 SYRDKKDHSSSRRGGFDRPSYD-------RKSDRPVYEGPSMFGGERRTYPEERMPLPAP 1798
KK+ ++ + + +K P + P + ++ PEE++P+P P
Sbjct: 9966 PVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEV---PKKPVPEEKVPVPVP 10022
Query: 1799 SLSHQPP-PAPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGL 1842
PP P V KKP + + P E+ P ++ + + L
Sbjct: 10023 KKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKL 10067
Score = 40.4 bits (93), Expect = 0.019
Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 9/96 (9%)
Query: 1471 EQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPP---PMGKPPGSIVR 1527
E ++ ++ E ++A P +E + PPP P P K P I +
Sbjct: 10802 EVYEEPEEIAPEEEIA---PEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVP-VIKK 10857
Query: 1528 PSAPPARSSVP--VTRPPVPIPPPPPPPPLPPPPPV 1561
P APP + P V P P PPPPPP PP V
Sbjct: 10858 PEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893
Score = 40.0 bits (92), Expect = 0.025
Identities = 86/426 (20%), Positives = 141/426 (33%), Gaps = 88/426 (20%)
Query: 1482 EPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTR 1541
+P++ P+ + +P + P + PPP + + P I P P
Sbjct: 10767 KPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIA-----PEEEIAPEEE 10821
Query: 1542 PPVPI----PPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKS 1597
PVP+ P PPP +P P I P E K
Sbjct: 10822 KPVPVAEEEEPEVPPPAVPEEPKKIIP-----------------------------EKKV 10852
Query: 1598 ETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIP 1657
P AP P I P P PP PP + I KV + P
Sbjct: 10853 PVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKP 10912
Query: 1658 -YGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETH 1716
E++ L P +P G++ +R+P + + V+
Sbjct: 10913 QVPEKVELTPLKVP---------GGEKKVRKLLPERKP--EPKEEVVL------------ 10949
Query: 1717 RDRDRDRGVIDYDRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGFDRPSYDRKSDRPVYE 1776
+ V+ R R + + + K ++ P + + E
Sbjct: 10950 ------KSVL-----------RKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE--VE 10990
Query: 1777 GPSMFGGERRTYPEERMPLPAPSLSHQPPPAPRVEKKPESKNVDDILKPPGRESRPERIV 1836
P++ ER+ ++P P++ P PAP + KPE++ +KPP E P I
Sbjct: 10991 VPTVTKRERKIPEPTKVPEIKPAI---PLPAPEPKPKPEAE--VKTIKPPPVEPEPTPIA 11045
Query: 1837 VIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKV 1896
+ +P GK AK +++ + GP V I E E+ + P SG +
Sbjct: 11046 APVT-VPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPI-EAERRKLRPGSGGEKPPDE 11103
Query: 1897 MEYEYE 1902
+ Y+
Sbjct: 11104 APFTYQ 11109
Score = 37.7 bits (86), Expect = 0.12
Identities = 43/251 (17%), Positives = 99/251 (39%), Gaps = 36/251 (14%)
Query: 1602 IPSAPV--LPPPPVHSSIPPPGPVPMGMPPMSKPPP----VQQTVDYGHGRDISTNKVEQ 1655
IP+ P+ +PP + + PP P+ + P KPPP V + + + E
Sbjct: 8944 IPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEM 9003
Query: 1656 IPYGERITLRPDP---LPERSTFETEHAGQRD---------RYDRERDREPYFDRQSNVI 1703
P E + P P +P ++ + + + + + + ++++E ++++ V
Sbjct: 9004 TPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVH 9063
Query: 1704 ADHRDFKRDRETHRDRDR-------------DRGVIDYDRDRFDRERRPRDDRAQSYRDK 1750
+ R F E D + DY+ + + ++ ++ + + +
Sbjct: 9064 KEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEG 9123
Query: 1751 KDHSSSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPE-ERMPLPAPSLSHQPPPAPR 1809
+++ R G+D + + Y+ + ++ Y E +PA + PP P+
Sbjct: 9124 QEY-YEREEGYDEGEEEWEE---AYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPK 9179
Query: 1810 VEKKPESKNVD 1820
V KKP + ++
Sbjct: 9180 VIKKPVIEKIE 9190
Score = 37.0 bits (84), Expect = 0.21
Identities = 38/141 (26%), Positives = 51/141 (36%), Gaps = 13/141 (9%)
Query: 1507 PPPG---SYRPPPPMGKPPGSIVRPSAPPAR-SSVP--------VTRPPVPIPPPPPPPP 1554
PP G S + PP KPP +V PPA+ VP V P P PP P
Sbjct: 10439 PPKGPEISEKIIPPK-KPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPE 10497
Query: 1555 LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVH 1614
+ PP V+ + V + E + + E + P P P V
Sbjct: 10498 VLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVP 10557
Query: 1615 SSIPPPGPVPMGMPPMSKPPP 1635
+ P VP +PP + PP
Sbjct: 10558 KAAVPEKKVPEAIPPKPESPP 10578
Score = 37.0 bits (84), Expect = 0.21
Identities = 31/117 (26%), Positives = 46/117 (39%), Gaps = 21/117 (17%)
Query: 1468 EQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP--PGSI 1525
E KE++ P+ + P E + +P + PP PP P+ + P
Sbjct: 10942 EPKEEVVLKSVLRKRPEEEE--PKVEPKKLEKVKKPAVPEPP----PPKPVEEVEVPTVT 10995
Query: 1526 VRPSAPPARSSVPVTRPPVPIPPPPP------------PPPL-PPPPPVIKPQTSAV 1569
R P + VP +P +P+P P P PPP+ P P P+ P T V
Sbjct: 10996 KRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPV 11052
Score = 34.7 bits (78), Expect = 1.0
Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 12/128 (9%)
Query: 1785 RRTYPEERMPLPAPSLSHQPPP-APRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLP 1843
++ PEER P+P PPP P + KKP + + P +++ P R V
Sbjct: 9404 KKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEV------ 9457
Query: 1844 GSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFITEVEK----EEKDPDSGKKVKKKVMEY 1899
S KT V + E + P+ + + + ++ E+ EE++ S +++ E
Sbjct: 9458 -SKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREE 9516
Query: 1900 EYEAEMEE 1907
E EAE+ E
Sbjct: 9517 EEEAEVTE 9524
Score = 34.7 bits (78), Expect = 1.0
Identities = 34/157 (21%), Positives = 53/157 (33%), Gaps = 48/157 (30%)
Query: 1527 RPSAPP-----ARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYG 1581
+P APP + +P +PP + P PP P P + VE
Sbjct: 10435 KPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVP----KKIVVE----------- 10479
Query: 1582 LWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPG-------PVPMGMPPMSKPP 1634
E +P P +PP V +PP PVP P + PP
Sbjct: 10480 ----------------EKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPP 10523
Query: 1635 PVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPE 1671
V + +++ K +P ++ + P +PE
Sbjct: 10524 KVPEA-----PKEVVPEKKVPVPPPKKPEVPPTKVPE 10555
Score = 34.3 bits (77), Expect = 1.4
Identities = 29/126 (23%), Positives = 50/126 (39%), Gaps = 9/126 (7%)
Query: 1452 QHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPP---QESRLQNTSSRPGMYPP 1508
+ E++LK+ + E+ + K + +P + + PP +E + + R P
Sbjct: 10944 KEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPE 11003
Query: 1509 PGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI--KPQT 1566
P P KP + P P + T P P+ P P P P PV+ K +
Sbjct: 11004 PTKV----PEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEA 11059
Query: 1567 SAVEQE 1572
A ++E
Sbjct: 11060 KAPKEE 11065
Score = 32.3 bits (72), Expect = 5.1
Identities = 27/92 (29%), Positives = 34/92 (36%), Gaps = 14/92 (15%)
Query: 606 PPPSLSSTAPPPVMPLPPLSSATPPPGIPP---PGVPQGIPPQLTAAPVP-------PAS 655
PP S P P MP+ A PP IPP P +P +P P P A
Sbjct: 8934 PPDIPDSRVPIPTMPI----RAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAV 8989
Query: 656 SSQSSQVPEKPRPALLPTPVSFGSAPPTTYHP 687
+ +V KP+ + PPTT P
Sbjct: 8990 KKDAKKVVAKPKEMTPREEIVKKPPPPTTLIP 9021
Score = 32.3 bits (72), Expect = 5.1
Identities = 48/224 (21%), Positives = 81/224 (36%), Gaps = 50/224 (22%)
Query: 1461 QELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGK 1520
+E ++L E++E L + ++ E + +PP+E + PP Y P
Sbjct: 10122 EEEEVLPEEEEVLPEEEEVLPEEE---EIPPEEEEV----------PPEEEYVPEEEEFV 10168
Query: 1521 PPGSIVRPSAP--PARSSVP-----VTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQER 1573
P ++ P P + VP VT V IP PP P K + + +
Sbjct: 10169 PEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPK 10228
Query: 1574 WDEDSFYGLWDTNDEQGLNSEFKSETA--------------------AIPSAPVLPPPPV 1613
+E + + +E+ ++ E E A+P AP P V
Sbjct: 10229 EEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKV 10288
Query: 1614 HSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIP 1657
+ PP V +P P PVQ+ ++ KV ++P
Sbjct: 10289 EA---PPAKVSKKIPEEKVPVPVQK-------KEAPPAKVPEVP 10322
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 110 bits (276), Expect = 1e-23
Identities = 107/317 (33%), Positives = 129/317 (40%), Gaps = 73/317 (23%)
Query: 517 PPPFVPYSQMPPPLPTM-----PPPVLPPSLPPPVMPPALP-ATVPPP------GMPPPV 564
PPP +P + +PPP P PPP LP + PP PP LP A +PPP G+PPP
Sbjct: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPP- 1055
Query: 565 MPPSLPTSVPPPGMPPSLSSAG--PPPVL------PPPSLSSAG--PPPVL------PPP 608
P LP + PP PP L AG PPP L PPP L AG PPP L PPP
Sbjct: 1056 --PPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111
Query: 609 SLSSTAPPPVMPLPPLSSATPPP----GIPPP------GVPQGIPPQLTAAPVPPASSSQ 658
L PP PLP PPP GIPPP G+P PP L A +PP
Sbjct: 1112 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP--PPPLPGAGIPPPPPLP 1169
Query: 659 SSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQ 718
+ +P P P P G PP PPL G + PL + +P
Sbjct: 1170 GAGIPPPP-----PLP-GVGIPPP----PPLPGVG----IPPPPPLPGAGIPPPPPLPGM 1215
Query: 719 GLGESSAAPSQ------------PITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPR 766
G+ + A P P++ +P LP P +L P G
Sbjct: 1216 GIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLG 1275
Query: 767 RFEDLGSRCEGPRPKGP 783
+D GSR + P P
Sbjct: 1276 MNQDKGSRKQPIEPCRP 1292
Score = 110 bits (275), Expect = 1e-23
Identities = 92/260 (35%), Positives = 109/260 (41%), Gaps = 48/260 (18%)
Query: 517 PPPFVPYSQMPPPLPTM-----PPPVLPPSLPPPVMPPALP-ATVPPP------GMPPPV 564
PPP +P + +PPP P PPP LP + PP PP LP A +PPP G+PPP
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPP- 1099
Query: 565 MPPSLPTSVPPPGMPPSLSSAGPPP-----VLPPPSLSSAG--PPPVLP------PPSLS 611
PP +PPP P PPP + PPP L AG PPP LP PP L
Sbjct: 1100 -PPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 612 STAPPPVMPLPPLSSATPPP----GIPPPGVPQGI----PPQLTAAPVPPASSSQSSQVP 663
PP PLP PPP GIPPP G+ PP L A +PP +P
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIP 1218
Query: 664 EKPRPALLPTPVSFGSAP--PTTYHPPLQSAG----PSEQVNSKAPLSKSALPYSSFSSD 717
P P L P P P + P L G P+ QV P LP F
Sbjct: 1219 PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLP---PPLPSGLFG-- 1273
Query: 718 QGLGESSAAPSQPITAVKDM 737
G+ + + QPI + M
Sbjct: 1274 LGMNQDKGSRKQPIEPCRPM 1293
Score = 107 bits (267), Expect = 1e-22
Identities = 91/281 (32%), Positives = 113/281 (40%), Gaps = 53/281 (18%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPV-------MPPALPATVPPPGMPPPVMPPSL 569
PPP +PPP P +P +PP PPP+ +PP A +PPP PP+ ++
Sbjct: 899 PPPLQGTEMLPPPPPPLPGAGIPP--PPPLPGAGILPLPPLPGAGIPPP---PPLPGAAI 953
Query: 570 PTSVPPPG----MPPSLSSAG--PPPVLP------PPSLSSAGPPPVLPPPSLSSTAPPP 617
P P PG +PP L AG PPP LP PP L AG PP P P PPP
Sbjct: 954 PPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1013
Query: 618 -----VMPLPPLSSA--TPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPAL 670
+ P PPL A PPP +P G+P PP L A +PP + +P P
Sbjct: 1014 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPP---- 1067
Query: 671 LPTPVSFGSAPPTTYHPPLQSAG-------PSEQVNSKAPLSKSALPYSSFSSDQGLGES 723
P P G PP PPL AG P + PL +P G+
Sbjct: 1068 -PLP-GAGIPPP----PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI--- 1118
Query: 724 SAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDG 764
P P + P G +P PP + P P G
Sbjct: 1119 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPG 1159
Score = 97.8 bits (242), Expect = 1e-19
Identities = 92/272 (33%), Positives = 109/272 (40%), Gaps = 55/272 (20%)
Query: 516 MPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPP 575
+PPP PPPLP M P LP + P PP L T +PPP PP LP + P
Sbjct: 876 VPPP-------PPPLPGMTVPTLPSTAIP--QPPPLQGTEM---LPPP--PPPLPGAGIP 921
Query: 576 PGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPP---- 631
P PP L AG +LP P L AG P PPP L A PP PLP PPP
Sbjct: 922 P--PPPLPGAG---ILPLPPLPGAGIP---PPPPLPGAAIPPPPPLPGAGIPLPPPLPGA 973
Query: 632 GIPPP------GVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPAL------LPTPVSFGS 679
GIPPP G+P PP L A +PP + +P P P L P P+
Sbjct: 974 GIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPPPPPLPGAG 1029
Query: 680 APPTTYHPPLQSAG-------PSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPIT 732
PP PPL AG P + PL + +P G+ P P
Sbjct: 1030 IPPP---PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI---PPPPPLPGA 1083
Query: 733 AVKDMPVRSGGLLPDPPRSSYLESPRGPRFDG 764
+ P G +P PP + P P G
Sbjct: 1084 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG 1115
Score = 95.5 bits (236), Expect = 5e-19
Identities = 89/285 (31%), Positives = 113/285 (39%), Gaps = 64/285 (22%)
Query: 513 NMSMPPPFVPYSQMPPPLPTM-----PPPVLP----PSLPPPVM--PPALPATVPPPGMP 561
N+ PPP +P ++ +P + PPP LP P+LP + PP L T P P
Sbjct: 854 NIPSPPP-LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPP 912
Query: 562 PPVMPPSLPTSVPPPG-----MPPSLSSAGPPP-------VLPPPSLSSAG---PPP--- 603
PP+ +P P PG +PP + PPP + PPP L AG PPP
Sbjct: 913 PPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPG 972
Query: 604 --VLPPPSLSSTAPPPVMPLPPLSSATPPP----GIPPP------GVPQGIPPQLTAAPV 651
+ PPP L PP PLP PPP GIPPP G+P PP L A +
Sbjct: 973 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGI 1030
Query: 652 PPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAG-------PSEQVNSKAPL 704
PP + +P P P P G PP PPL AG P + PL
Sbjct: 1031 PPPPPLPGAGIPPPP-----PLP-GAGIPPP----PPLPGAGIPPPPPLPGAGIPPPPPL 1080
Query: 705 SKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPP 749
+ +P G+ P P + P G +P PP
Sbjct: 1081 PGAGIPPPPPLPGAGI---PPPPPLPGVGIPPPPPLPGAGIPPPP 1122
Score = 76.6 bits (187), Expect = 2e-13
Identities = 98/389 (25%), Positives = 124/389 (31%), Gaps = 113/389 (29%)
Query: 10 GSSHYPPPP-----VPPPPPV---ALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQL 61
G+ PPPP +PPPPP+ +P P PG P P +
Sbjct: 939 GAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAG------------- 985
Query: 62 QQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMP----PPPGPALSY 117
+ P LP +PPPP +PG G PPPPP+P PPP P
Sbjct: 986 -------------IPPPPPLPGAGIPPPPPLPGAGI----PPPPPLPGAGIPPPPPLPGA 1028
Query: 118 QKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ---SYMPPPQP-PPS 173
G P P+ P PP+P PP + +PPP P P +
Sbjct: 1029 ----------------GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1072
Query: 174 YYPPTSSQPY--LPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQAS 231
PP P +PP P P P P P LP +
Sbjct: 1073 GIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGVGIPPPPP----------LPGAGIP 1119
Query: 232 PSRPSQGHSKSQLLAPPPP-------SAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD 284
P P G + PPPP PP + + P GA A P
Sbjct: 1120 PPPPLPGAG----IPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175
Query: 285 PSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPE 344
P + V +P P V P P+ +P +P
Sbjct: 1176 PPPLPG--------------------VGIPPPPPLPGVGIPPPPPLPG-AGIPPPPPLPG 1214
Query: 345 S--PSSEEPPLPPPNEEVPPP--LPPEEP 369
P + PPLPPP +PPP LP P
Sbjct: 1215 MGIPPAPAPPLPPPGTGIPPPPLLPVSGP 1243
Score = 67.4 bits (163), Expect = 1e-10
Identities = 96/378 (25%), Positives = 114/378 (30%), Gaps = 127/378 (33%)
Query: 19 VPPPPPVALPEAS-----------PGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQM 67
+P PPP+ E+S P P T P PS++ + Q
Sbjct: 855 IPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTA---------------IPQP 899
Query: 68 HQKQMQCVLQPHHLPPPPLP-----PPPVMPGGGY-------GDWQPPPPPM------PP 109
Q +L P PPPPLP PPP +PG G G PPPPP+ PP
Sbjct: 900 PPLQGTEMLPP---PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956
Query: 110 PPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESP--PVPPGSYMPPSQSYMPP 167
PP P PP L + PP P +PP +P + PP
Sbjct: 957 PPLPGAGIPL---------------PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001
Query: 168 PQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPS 227
P P PP P LP A P P P P LP
Sbjct: 1002 PLPGAGIPPP----PPLPGAGIPPPPPLPGAGIPPPPP-------------------LPG 1038
Query: 228 SQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPST 287
+ P P G PPPP P + P GA A P P
Sbjct: 1039 AGIPPPPPLPGAG-----IPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPP 1090
Query: 288 MTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPS 347
LPG A P P V +P +P +
Sbjct: 1091 -------------------------LPG-------AGIPPPPPLPGVGIPPPPPLPGAGI 1118
Query: 348 SEEPPLPPPNEEVPPPLP 365
PPLP PPPLP
Sbjct: 1119 PPPPPLPGAGIPPPPPLP 1136
Score = 67.0 bits (162), Expect = 2e-10
Identities = 67/248 (27%), Positives = 84/248 (33%), Gaps = 49/248 (19%)
Query: 17 PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVL 76
PP PP P +P P PG P P + +
Sbjct: 1086 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAG--------------------------IP 1119
Query: 77 QPHHLPPPPLPPPPVMPGGGYGDWQPPPPPM------PPPPGPALSYQKQQQYKHQMLHH 130
P LP +PPPP +PG G PPPPP+ PPPP P +
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGI----PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGI-- 1173
Query: 131 QRDGPPGLVPMELESPPESPPV--PPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP-- 186
PP L + + PP P V PP +P + +PPP P P P + P LPP
Sbjct: 1174 --PPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAG--IPPPPPLPGMGIPPAPAPPLPPPG 1229
Query: 187 -AQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLL 245
P P P S L P SS+ + LPS S+ Q +
Sbjct: 1230 TGIPPPPLLPVSGPPL--LPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPI 1287
Query: 246 APPPPSAP 253
P P P
Sbjct: 1288 EPCRPMKP 1295
Score = 65.9 bits (159), Expect = 4e-10
Identities = 58/169 (34%), Positives = 69/169 (40%), Gaps = 36/169 (21%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPP-PGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTR 1541
P + PQ LQ T P PP PG+ PPPP G + P P A P
Sbjct: 889 PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL 948
Query: 1542 PPVPIPPPPP--------PPPLP----PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQ 1589
P IPPPPP PPPLP PPPP P A G+
Sbjct: 949 PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPP---PLPGA------------GIPPPPPLP 993
Query: 1590 GLNSEFKSETAAIPSAPVLPPPPV-HSSIPPPGPVP-MGMPPMSKPPPV 1636
G +P A + PPPP+ + IPPP P+P G+PP PPP+
Sbjct: 994 GAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPPL 1036
Score = 62.4 bits (150), Expect = 5e-09
Identities = 46/137 (33%), Positives = 58/137 (42%), Gaps = 44/137 (32%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIP----PPPPPPP---LPPPP 1559
P PG+ PPPP PG+ + P P R +P PP P+P PPPPP P +PPPP
Sbjct: 1123 PLPGAGIPPPP--PLPGAGIPPPPPLPRVGIP---PPPPLPGAGIPPPPPLPGAGIPPPP 1177
Query: 1560 PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV-HSSIP 1618
P L +P + PPPP+ + IP
Sbjct: 1178 P------------------------------LPGVGIPPPPPLPGVGIPPPPPLPGAGIP 1207
Query: 1619 PPGPVP-MGMPPMSKPP 1634
PP P+P MG+PP PP
Sbjct: 1208 PPPPLPGMGIPPAPAPP 1224
Score = 62.4 bits (150), Expect = 5e-09
Identities = 58/198 (29%), Positives = 71/198 (35%), Gaps = 71/198 (35%)
Query: 10 GSSHYPPPP-----VPPPPP---VALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQL 61
G+ PPPP +PPPPP V +P P PG P P +
Sbjct: 1126 GAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG------------- 1172
Query: 62 QQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMP----PPPGPALSY 117
+ P LP +PPPP +PG G PPPPP+P PPP P
Sbjct: 1173 -------------IPPPPPLPGVGIPPPPPLPGVGI----PPPPPLPGAGIPPPPPL--- 1212
Query: 118 QKQQQYKHQMLHHQRDGPPGLVPMELESPPESPP---VPPGSYMPPSQSYMPP--PQPPP 172
PG+ +PP PP +PP +P S PP PQ
Sbjct: 1213 ------------------PGMGIPPAPAPPLPPPGTGIPPPPLLPVSG---PPLLPQVGS 1251
Query: 173 SYYPPTSSQPYLPPAQPS 190
S P +LPP PS
Sbjct: 1252 STLPTPQVCGFLPPPLPS 1269
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/143 (33%), Positives = 64/143 (44%), Gaps = 44/143 (30%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIP----PPPPPPP---LPPPP 1559
P PG+ PPPP PG+ + P P + +P PP P+P PPPPP P +PPPP
Sbjct: 1046 PLPGAGIPPPP--PLPGAGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPP 1100
Query: 1560 PV----IKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV-H 1614
P+ I P L +P A + PPPP+
Sbjct: 1101 PLPGVGIPPPPP-----------------------LPGAGIPPPPPLPGAGIPPPPPLPG 1137
Query: 1615 SSIPPPGPVP-MGMPPMSKPPPV 1636
+ IPPP P+P +G+PP PPP+
Sbjct: 1138 AGIPPPPPLPRVGIPP---PPPL 1157
Score = 59.7 bits (143), Expect = 3e-08
Identities = 46/139 (33%), Positives = 62/139 (44%), Gaps = 47/139 (33%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIP----PPPPPPP---LPPPP 1559
P PG+ PPPP PG + P P + +P PP P+P PPPPP P +PPPP
Sbjct: 1090 PLPGAGIPPPP--PLPGVGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPP 1144
Query: 1560 PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV-HSSIP 1618
P+ P+ +P A + PPPP+ + IP
Sbjct: 1145 PL--PRVGI----------------------------PPPPPLPGAGIPPPPPLPGAGIP 1174
Query: 1619 PPGPVP-MGMPPMSKPPPV 1636
PP P+P +G+PP PPP+
Sbjct: 1175 PPPPLPGVGIPP---PPPL 1190
Score = 59.3 bits (142), Expect = 4e-08
Identities = 60/181 (33%), Positives = 78/181 (43%), Gaps = 47/181 (25%)
Query: 1490 PPQESRLQNTSSRPG--MYPPPGSYRPPPPMGKPPG-------SIVRPSAPPARSSVPVT 1540
PP +++SS PG M PP PPPP+ PG S P PP + + +
Sbjct: 858 PPPLPCTESSSSMPGLGMVPP-----PPPPL---PGMTVPTLPSTAIPQPPPLQGTEMLP 909
Query: 1541 RPPVPIP----PPPPP---------PPLP----PPPPVIKPQTSAVEQERWDEDSFYGLW 1583
PP P+P PPPPP PPLP PPPP + +A+ + L
Sbjct: 910 PPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL--PGAAIPPPPPLPGAGIPLP 967
Query: 1584 DTNDEQGLNSEFKSETAAIPSAPVL------PPPPV-HSSIPPPGPVP-MGMPPMSKPPP 1635
G+ A IP P L PPPP+ + IPPP P+P G+PP PPP
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPP 1024
Query: 1636 V 1636
+
Sbjct: 1025 L 1025
Score = 59.3 bits (142), Expect = 4e-08
Identities = 46/139 (33%), Positives = 60/139 (43%), Gaps = 47/139 (33%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIP----PPPPPPP---LPPPP 1559
P PG+ PPPP PG+ + P P + +P PP P+P PPPPP P +PPPP
Sbjct: 991 PLPGAGIPPPP--PLPGAGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPP 1045
Query: 1560 PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV-HSSIP 1618
P L +P A + PPPP+ + IP
Sbjct: 1046 P------------------------------LPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1075
Query: 1619 PPGPVP-MGMPPMSKPPPV 1636
PP P+P G+PP PPP+
Sbjct: 1076 PPPPLPGAGIPP---PPPL 1091
Score = 59.3 bits (142), Expect = 4e-08
Identities = 45/139 (32%), Positives = 59/139 (42%), Gaps = 58/139 (41%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIP----PPPPPPP---LPPPP 1559
P PG+ PPPP PG+ + P P + +P PP P+P PPPPP P +PPPP
Sbjct: 1112 PLPGAGIPPPP--PLPGAGIPPPPPLPGAGIP---PPPPLPRVGIPPPPPLPGAGIPPPP 1166
Query: 1560 PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHS-SIP 1618
P +P A + PPPP+ IP
Sbjct: 1167 P-----------------------------------------LPGAGIPPPPPLPGVGIP 1185
Query: 1619 PPGPVP-MGMPPMSKPPPV 1636
PP P+P +G+PP PPP+
Sbjct: 1186 PPPPLPGVGIPP---PPPL 1201
Score = 58.2 bits (139), Expect = 9e-08
Identities = 55/180 (30%), Positives = 72/180 (40%), Gaps = 44/180 (24%)
Query: 1471 EQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSA 1530
E M G P LP +++ P P G+ PPP PG+ + P
Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP 924
Query: 1531 P-PARSSVPVTRPPVP---IPPPPPPP--PLPPPPPVIKPQTSAVEQERWDEDSFYGLWD 1584
P P +P+ PP+P IPPPPP P +PPPPP+
Sbjct: 925 PLPGAGILPL--PPLPGAGIPPPPPLPGAAIPPPPPL----------------------- 959
Query: 1585 TNDEQGLNSEFKSETAAIPSAPVL------PPPPV-HSSIPPPGPVP-MGMPPMSKPPPV 1636
G+ A IP P L PPPP+ + IPPP P+P G+PP PPP+
Sbjct: 960 --PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP---PPPL 1014
Score = 57.8 bits (138), Expect = 1e-07
Identities = 46/137 (33%), Positives = 58/137 (42%), Gaps = 40/137 (29%)
Query: 1504 GMYPPPGSYR----PPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP--PPPPPLP- 1556
G+ PPP R PPPP+ PG+ + P P + +P PP P+P PPPPPLP
Sbjct: 1139 GIPPPPPLPRVGIPPPPPL---PGAGIPPPPPLPGAGIP---PPPPLPGVGIPPPPPLPG 1192
Query: 1557 ---PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV 1613
PPPP P A G+ IP AP P PP
Sbjct: 1193 VGIPPPP---PLPGA---------------------GIPPPPPLPGMGIPPAPAPPLPPP 1228
Query: 1614 HSSIPPPGPVPMGMPPM 1630
+ IPPP +P+ PP+
Sbjct: 1229 GTGIPPPPLLPVSGPPL 1245
Score = 53.5 bits (127), Expect = 2e-06
Identities = 55/206 (26%), Positives = 76/206 (36%), Gaps = 15/206 (7%)
Query: 160 PSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLS 219
P+QS PP PP + QP +QP S S Q+ + +S SS+ S
Sbjct: 803 PTQSISQPPPPPSLLWSAGQGQP---GSQPPHSISTEFQT----SHEHSVSSAFKNSCNI 855
Query: 220 HSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQA 279
S LP +++S S P G ++ PPPP P T+ + + TE
Sbjct: 856 PSPPPLPCTESSSSMPGLG-----MVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP 910
Query: 280 APEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPAT 339
P P P P +L L +P P A P P+ +P
Sbjct: 911 PPPPLPGAGIPPPPPLPG--AGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG-AGIPLP 967
Query: 340 SQVPESPSSEEPPLPPPNEEVPPPLP 365
+P + PPLP PPPLP
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLP 993
Score = 46.2 bits (108), Expect = 3e-04
Identities = 62/260 (23%), Positives = 89/260 (34%), Gaps = 60/260 (23%)
Query: 54 REQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGP 113
++Q QLQ QQ Q+Q+Q +P PP + P PG
Sbjct: 208 QQQQQLQLQLQQQQQQQQLQGAEEP----------------------AAPPTAVSPQPGA 245
Query: 114 ALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMP--PPQPP 171
L + GP G SP + S +P S + P P QPP
Sbjct: 246 FLGLDRFLL-----------GPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPP 294
Query: 172 PSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSS-------QSYLSHSQSY 224
P S P LP AQP+ SP S ++ P ++ + ++
Sbjct: 295 SPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAF 354
Query: 225 LPSSQASPSR---PSQGHSKSQLLAPPP------PSAP-----PGNKTTVQQ----EPLE 266
+ + SP P G Q L P P AP PG+ Q+ PL
Sbjct: 355 EDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLI 414
Query: 267 SGAKNKSTEQQQAAPEPDPS 286
+ K+T +Q ++P PS
Sbjct: 415 TPCYIKTTTRQLSSPNHSPS 434
Score = 45.8 bits (107), Expect = 4e-04
Identities = 44/152 (28%), Positives = 59/152 (38%), Gaps = 32/152 (21%)
Query: 1516 PPMGKPPGSIVRPSAPPARSSVPVT-------------RPPVPIPPPPPPPPL--PPPPP 1560
PP+ PG RP PP S P T R V + P + PPPPP
Sbjct: 758 PPVDGLPG---RPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPP 814
Query: 1561 VIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP 1620
+ + S + T+ E ++S FK+ + IPS P LP SS+P
Sbjct: 815 SLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKN-SCNIPSPPPLPCTESSSSMPGL 873
Query: 1621 GPVPMGMPPM-------------SKPPPVQQT 1639
G VP PP+ +PPP+Q T
Sbjct: 874 GMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT 905
Score = 43.5 bits (101), Expect = 0.002
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 12/73 (16%)
Query: 1504 GMYPPPG----SYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP----PPPPPL 1555
G+ PPP PPPP+ PG+ + P P +P P P+PPP PPPP L
Sbjct: 1183 GIPPPPPLPGVGIPPPPPL---PGAGIPPPPPLPGMGIPPAPAP-PLPPPGTGIPPPPLL 1238
Query: 1556 PPPPPVIKPQTSA 1568
P P + PQ +
Sbjct: 1239 PVSGPPLLPQVGS 1251
Score = 36.2 bits (82), Expect = 0.36
Identities = 20/53 (37%), Positives = 24/53 (45%)
Query: 1504 GMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP 1556
G+ P P PPP G PP ++ S PP V + P P PPPLP
Sbjct: 1216 GIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 35.4 bits (80), Expect = 0.61
Identities = 38/156 (24%), Positives = 48/156 (30%), Gaps = 56/156 (35%)
Query: 17 PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVL 76
PP PP P +P P PG PA P L
Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAPP------------------------------L 1225
Query: 77 QP--HHLPPPPLPP---PPVMPGGGYGDWQPP------PPPMP---------------PP 110
P +PPPPL P PP++P G P PPP+P
Sbjct: 1226 PPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQ 1285
Query: 111 PGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESP 146
P K + LH +RD L+ ++E P
Sbjct: 1286 PIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEP 1321
Score = 35.0 bits (79), Expect = 0.79
Identities = 53/231 (22%), Positives = 73/231 (31%), Gaps = 38/231 (16%)
Query: 15 PPPPVPPPPP--VALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
PP V P P + L GP + P +P + EQ L+ L L + +
Sbjct: 235 PPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDT-------EQALSALSDLPESLAAEP 287
Query: 73 QCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPP--GPALSY---------QKQQ 121
+ QP P+ P +P P P P GP +
Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDE 347
Query: 122 QYKHQMLHHQRDGPPGL---------VPMELESPPES----PPVP-----PGSYMPPSQS 163
+ + G PG P L PE P P PGS P +
Sbjct: 348 EGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRC 407
Query: 164 YMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSS 214
+ P P P Y T+ Q P PS S + + P PS S S ++
Sbjct: 408 FKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTA 458
Score = 33.1 bits (74), Expect = 3.0
Identities = 49/195 (25%), Positives = 60/195 (30%), Gaps = 41/195 (21%)
Query: 176 PPTSSQPYLPPAQPSPSQSPPSQ-----SYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQA 230
PP P PP P P ++ S + S S Q S SQ P S
Sbjct: 758 PPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLL 817
Query: 231 SPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTP 290
+ QG SQ PP + T + + S KN P P P T
Sbjct: 818 WSA--GQGQPGSQ-----PPHSISTEFQTSHEHSVSSAFKNSCN-----IPSPPPLPCTE 865
Query: 291 QEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEE 350
+PG G V P P T+P+T+ P
Sbjct: 866 SSSS------------------MPG--LGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGT 905
Query: 351 PPLPPPNEEVPPPLP 365
LPPP PPPLP
Sbjct: 906 EMLPPP----PPPLP 916
Score = 32.7 bits (73), Expect = 3.9
Identities = 54/206 (26%), Positives = 68/206 (33%), Gaps = 32/206 (15%)
Query: 538 LPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLS 597
LP SL P P P PG P PSLP + P PS S+A P P P
Sbjct: 279 LPESL---AAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPS-STAFPFPEAGPG--E 332
Query: 598 SAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAP------- 650
A PV P S P P V + P +L P
Sbjct: 333 EAAGAPVRGAGDTDEEGEEDAFEDAPRGS---PGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
Query: 651 -VPPASSSQSSQVPE----KPRPALLPTPVSFGSAP-PTTYHPPLQSAGPSEQV------ 698
P A+S S P KP P + P + + + H P QS S ++
Sbjct: 390 DAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
Query: 699 ----NSKAPLSKSALPYSSFSSDQGL 720
S+ L+ A P +D GL
Sbjct: 450 SLSRGSRTALASVAAPAKKHRADGGL 475
Score = 32.0 bits (71), Expect = 6.7
Identities = 36/166 (21%), Positives = 64/166 (38%), Gaps = 15/166 (9%)
Query: 1415 PMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQ 1474
P+AE + ++ + + G S SD + ++ Q +++ Q +++ ++Q++QLQ
Sbjct: 158 PIAEDVETAAGAQD--GQRTSSGSDTDIYSFHSATE-QEDLLSDIQQAIRLQQQQQQQLQ 214
Query: 1475 KMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYR--PPPPMGKPPGSIVRPSAPP 1532
+ Q + S +PG + + P G+ PGS A
Sbjct: 215 LQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALS 274
Query: 1533 ARSSVPVTRPPVPIPPPPPP----------PPLPPPPPVIKPQTSA 1568
A S +P + P P PP P LP P K S+
Sbjct: 275 ALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSS 320
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 109 bits (273), Expect = 3e-23
Identities = 103/331 (31%), Positives = 131/331 (39%), Gaps = 50/331 (15%)
Query: 517 PP--PFVPYS-----QMPPPLPTMPP-PVLPPSLPPPVMPPALPATVPPPGMPPPVM--- 565
PP P P+S Q+ PLP PP P PPSL PPA P + + P +
Sbjct: 318 PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 377
Query: 566 ------PPSLPTSVPPPGMPPSLS----SAGPPPVLPPPSLSSAGPPPVLPPP----SLS 611
PP P + PPP PP+L+ A P P PP A P P P L
Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
Query: 612 STAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKP--RPA 669
+ PP P PP+ + PP PP P PP + PP+ ++ QVP P P
Sbjct: 438 APFSPP--PSPPVQAPFSPPASPPVS-PSATPP----SQAPPSLAAPPLQVPPSPPASPP 490
Query: 670 LLPTPVSFGSAPPTTYHPPLQSAGPSEQVN---SKAPLSKSALPYSSFSSDQGLGESSAA 726
+ P+ APP PPLQ A P Q + PL P +SF S++
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
Query: 727 PSQPITAVKDM--PVRSGGLL---PDPPRSSYLESPRGPRFDGPRRFEDLGSR-----CE 776
P P+ PV + LL P PP S L++PR P GP G R
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-GPRLTLALAP 609
Query: 777 GPRPKGPRFEGNRPDGPRPRYEGHPAEGTKS 807
GP P R + G P GH + T +
Sbjct: 610 GPPPPPSRSPSSTLSG--PDLAGHSSSATST 638
Score = 98.6 bits (244), Expect = 6e-20
Identities = 99/330 (30%), Positives = 118/330 (35%), Gaps = 42/330 (12%)
Query: 517 PPPFVPYSQMPPPLPTMP-------------PPVLPP---SLPPPVMPPALPATVPPPGM 560
PP P S + P P P PP PP PP PP P+ PP
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470
Query: 561 PPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPP----PSLSSAGPPPVLPPPSLSSTAPP 616
PP + P L PP PP SA PPP PP P L A PPP PP +T P
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP--ALATPPL 528
Query: 617 PVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAP-VPPASSSQSSQVPEKPRPALLPTPV 675
+P PP S P P +P + P T P PP ++ QVP P PA +P
Sbjct: 529 QALPSPPASFPGQAPFSPSASLP--MSPLATPPPQAPPVLAAPLLQVPPSP-PA---SPT 582
Query: 676 SFGSAPPTTYHPPLQSAGP--SEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITA 733
P T P +GP + + P S P S+ S G SS+A S P
Sbjct: 583 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 642
Query: 734 VKDMPVRSGGLLPDPPRSSYLES------PRGPRFDGPRRFEDLGSRCEGPRPKGPRFEG 787
GG PP + L + RGP P F P P P
Sbjct: 643 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPG---APLPWPPATGP 697
Query: 788 NRPDGPRPRYEGHPAEGTKSKWGMIPRGPA 817
DG YE E G + GP+
Sbjct: 698 GSADGLCTIYETEGPESATPAPGALDPGPS 727
Score = 89.0 bits (219), Expect = 5e-17
Identities = 83/285 (29%), Positives = 101/285 (35%), Gaps = 28/285 (9%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75
P P+ PP P A P P + PA P S S LQ H
Sbjct: 337 PLPLAPPSPSAPPSLQTLP-----SPPATPPSQATTSLGSP------TLQATHSFLPSPP 385
Query: 76 LQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPAL--SYQKQQQYKHQMLHHQRD 133
L P PPP PP +P PP PP PP P S Q +L
Sbjct: 386 LSPLATPPPQAPPALALPPLQ----APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441
Query: 134 GPPGLVPMELESPPESPPVPPG----SYMPPSQSYMP---PPQPPPSYYPPTSSQPYLPP 186
PP SPP SPPV P S PPS + P PP PP S PP S PP
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS--PPMSPSATPPP 499
Query: 187 AQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLA 246
P P +PP Q P + + ++ L + P +P PS S L
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ--APFSPSASLPMSPLAT 557
Query: 247 PPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQ 291
PPP + P +Q P + ++ P PD S P+
Sbjct: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 602
Score = 75.5 bits (184), Expect = 5e-13
Identities = 103/401 (25%), Positives = 131/401 (32%), Gaps = 87/401 (21%)
Query: 2 YPNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQL 61
+P+ + G PP V PP +A+P G SS+ A PS S + Q A
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRK----DAAPALGPLSSSPLATPSPSAAL----QSQAPP 319
Query: 62 QQLQQMHQKQMQCVLQ-PHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ 120
H + C L P L PP PP + P PP PP
Sbjct: 320 TLPATPHSSSLTCQLATPLPLAPPSPSAPPSL------QTLPSPPATPPSQATTSLGSPT 373
Query: 121 QQYKHQMLHHQR---------DGPPGLVPMELESPPESPPVPPGSYMPPSQSYMP----- 166
Q H L PP L L++PP P PP S + P
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433
Query: 167 -----PPQPPPSYYPPTSSQPYLPPAQP--SPSQSPPSQSYLAPTPSYSSSSSSSQSYLS 219
P PPPS PP + P+ PPA P SPS +PPSQ+ PS ++
Sbjct: 434 HLLQAPFSPPPS--PPVQA-PFSPPASPPVSPSATPPSQA----PPSLAAPPLQVPPSPP 486
Query: 220 HSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQA 279
S PS+ P P + LA PPP APP T PL++ ++ QA
Sbjct: 487 ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP----PLQALPSPPASFPGQA 542
Query: 280 APEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPAT 339
P S P+ TP P V
Sbjct: 543 PFSPSASL--------------------------------PMSPLATPPPQAPPVLAAPL 570
Query: 340 SQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARL 380
QV PP PP + + P P P + RL
Sbjct: 571 LQV--------PPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603
Score = 69.7 bits (169), Expect = 3e-11
Identities = 73/264 (27%), Positives = 97/264 (36%), Gaps = 49/264 (18%)
Query: 511 MGNMSMPPPFVPYSQMPPPLP-TMPPPVLPPSL--PPPVMPPALPATVP--PPGMPPPVM 565
M + PPP P PPL PPP PP+L PP P+ PA+ P P P +
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
Query: 566 PPSLPTSVPPPGMPPSLSS---AGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLP 622
P S P + PPP PP L++ PP P+L + PP P P S + P + L
Sbjct: 551 PMS-PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT-PGPDTSVSGPRLTLALA 608
Query: 623 PLSSATPPPGIPPPGVPQG------------IPPQLTAAPVPPASSSQSSQVPEKPRPAL 670
P PPP P G P +L P + +S P+ A
Sbjct: 609 P--GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 666
Query: 671 LPTPVSFGSAPPTTYH---------PP-------------LQSAGPSEQVNSKAPLSKSA 708
P S G APP + PP ++ GP + L
Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726
Query: 709 LPYSS---FSSDQGLGESSAAPSQ 729
P +S ++ G G SS +P Q
Sbjct: 727 SPGTSGGKAAAGAGAGASSRSPKQ 750
Score = 66.2 bits (160), Expect = 3e-10
Identities = 85/312 (27%), Positives = 110/312 (35%), Gaps = 62/312 (19%)
Query: 14 YPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQ 73
+ PPP PP P ASP S++ AP S LQ
Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA-----------APPLQVPPSPPAS 488
Query: 74 CVLQPHHLPPPPLPPPPVMPGGGYGDWQPPP--------PPMPPPPGPALSYQKQQQYKH 125
+ P PPP PPP P +PPP PP+ P P S+ Q +
Sbjct: 489 PPMSPSATPPPQAPPPLAAPPLQLA--KPPPQAPPALATPPLQALPSPPASFPGQAPFS- 545
Query: 126 QMLHHQRDGPPGLVPME--LESPPESPPV--------PPGSYMPPSQSYMPPPQPPPSYY 175
P +PM PP++PPV PP PP+ + P+ PP+
Sbjct: 546 ---------PSASLPMSPLATPPPQAPPVLAAPLLQVPPS---PPASPTLQAPRRPPTPG 593
Query: 176 PPTS-SQPYL-----PPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQ 229
P TS S P L P P PS+SP S +SSS++S+ L S P
Sbjct: 594 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG-PEGG 652
Query: 230 ASPSRPSQG-----HSKSQLLAPPPPSAPPGNKTTVQQEPLESG---AKNKSTEQQQAAP 281
A+ S P H + P PP A G P +G A T + P
Sbjct: 653 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 712
Query: 282 E---PDPSTMTP 290
E P P + P
Sbjct: 713 ESATPAPGALDP 724
Score = 62.8 bits (151), Expect = 4e-09
Identities = 108/441 (24%), Positives = 140/441 (31%), Gaps = 111/441 (25%)
Query: 9 GGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAP-SSSGFMSFREQHLAQLQQLQQM 67
G PP P PV+ PG +S TT P G E+ +A+ + +
Sbjct: 98 GRGERAPPAKNTSPGPVS------SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 151
Query: 68 HQKQMQCVLQPHHLPPPPLPPPPVMP------GGGYGDWQPPPP--PMPPPPGPALSYQK 119
+ + + P P P P M G G +P P P PP GP S
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211
Query: 120 QQQYK----HQMLHHQRDGPPGLV----------PMELESPPESPPVPPGSYMPPS---- 161
++ + GL L SP S P G+ P+
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
Query: 162 ------QSYMPPPQPPP--------------------------SYYPPT-SSQPY----- 183
Q+ PP PP S PPT + P+
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331
Query: 184 ------LPPAQPSPSQSPPSQSYLAP--TPSYSSSSSSSQSYLSHSQSYLPSSQASPSRP 235
LP A PSPS P Q+ +P TP +++S L + S+LPS SP
Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP--- 388
Query: 236 SQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQ 295
LA PPP APP Q P A+P P TP Q
Sbjct: 389 ---------LATPPPQAPPALALPPLQAP----------PSPPASPPLSP-LATPSPQAP 428
Query: 296 YWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPP 355
HLL + PV A +P P V+ AT PS PPL
Sbjct: 429 NALAVHLL------QAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQV 481
Query: 356 PNEEVPPPLPPEEPQSEDPEE 376
P PP PP P + P +
Sbjct: 482 PPS--PPASPPMSPSATPPPQ 500
Score = 60.1 bits (144), Expect = 2e-08
Identities = 64/208 (30%), Positives = 83/208 (39%), Gaps = 41/208 (19%)
Query: 1481 SEPQMADHLPPQESRLQNTSSRPGMYPP----PGSYRPPPPMGKPPGSIVRPSA-PPARS 1535
S P A PP + +++ P PP P PP P PP S PSA PP ++
Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS---PSATPPPQA 501
Query: 1536 SVPVTRPPVPIPPPPP--PPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNS 1593
P+ PP+ + PPP PP L PP P A SF G +
Sbjct: 502 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA---------SFPG----------QA 542
Query: 1594 EFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKV 1653
F S +A++P +P+ PPP PP P+ P S PP T+ R T
Sbjct: 543 PF-SPSASLPMSPLATPPP---QAPPVLAAPLLQVPPS--PPASPTLQ--APRRPPTPGP 594
Query: 1654 EQIPYGERITLR----PDPLPERSTFET 1677
+ G R+TL P P P RS T
Sbjct: 595 DTSVSGPRLTLALAPGPPPPPSRSPSST 622
Score = 59.7 bits (143), Expect = 3e-08
Identities = 96/381 (25%), Positives = 122/381 (32%), Gaps = 42/381 (11%)
Query: 22 PPPVALPEASPGPGY--------SSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQ 73
P P A S G G SSS TP + + S R A Q K +Q
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP-SQPKPKGLQ 278
Query: 74 CVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPP----MPPPPGPALSYQKQQQYKHQMLH 129
+ P PP P + P P P PP PA + L
Sbjct: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS-------LT 331
Query: 130 HQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYM----PPPQPPPSYYP--PTSSQPY 183
Q P L P +PP +P PPSQ+ P Q S+ P P S
Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391
Query: 184 LPPAQP-----SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQG 238
PP P P Q+PPS P ++ S + + L+ P S PS P Q
Sbjct: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-PPPSPPVQA 450
Query: 239 HSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWY 298
P PSA P + Q P A A P + TP Q
Sbjct: 451 PFSPPASPPVSPSATPPS-----QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 505
Query: 299 RQHLLSLQQRTKVHLPGHKKGPVVA-KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPN 357
L L + P P+ A P + ++ +P SP + PP PP
Sbjct: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 358 EEVP----PPLPPEEPQSEDP 374
P PP PP P + P
Sbjct: 566 LAAPLLQVPPSPPASPTLQAP 586
Score = 59.3 bits (142), Expect = 4e-08
Identities = 94/367 (25%), Positives = 123/367 (33%), Gaps = 74/367 (20%)
Query: 556 PPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVL--PPPSLSSAGPPPVLPPP----- 608
P PG P P M + G+P SA P P P S+SSA P
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 609 --------------SLSSTAPPPVMPL--PPLSSATP----------PPGIPPPGVPQGI 642
SLSS+A P P P + TP P G+ PQ
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
Query: 643 PPQLTAAPV-------PPASSSQSSQVPEKPRPALLPTPVSFG----SAPPTTYHPPLQS 691
PP+ AAP P A+ S S+ + + P L TP S A P PP S
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346
Query: 692 AGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRS 751
A PS Q P + + +S S S PS P++ + P ++ L PP
Sbjct: 347 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP-- 404
Query: 752 SYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEG----NRPDGPRPRYEGHPAEGTKS 807
L++P P P S P P+ P P P P P + S
Sbjct: 405 --LQAPPSPPASPPL------SPLATPSPQAPNALAVHLLQAPFSPPP---SPPVQAPFS 453
Query: 808 KWGMIPRGPASQFYITPSTSLSPRQSGPQWKGP---------KPAFGQQHQQQPKSQAEP 858
P P++ TP + P + P + P P+ Q P A P
Sbjct: 454 PPASPPVSPSA----TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
Query: 859 LSGNKEP 865
L K P
Sbjct: 510 LQLAKPP 516
Score = 57.4 bits (137), Expect = 1e-07
Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 20/168 (11%)
Query: 1474 QKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPP----PGSYRPPPPMGKPPGSIVRPS 1529
Q GS A H L ++ P PP P PP P PP S +
Sbjct: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
Query: 1530 APPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQ 1589
+P A +++ V P PPP PP P P P S T Q
Sbjct: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA--------------TPPSQ 469
Query: 1590 GLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPP--MSKPPP 1635
S PS P PP ++ PP P P+ PP ++KPPP
Sbjct: 470 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517
Score = 53.5 bits (127), Expect = 2e-06
Identities = 61/225 (27%), Positives = 79/225 (35%), Gaps = 32/225 (14%)
Query: 511 MGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSL- 569
M ++ PPP P P L P P P+L P PP PG V P L
Sbjct: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT-------PGPDTSVSGPRLT 604
Query: 570 ----PTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVL-----PPPSLSSTAPPPVMP 620
P PPP PS + +GP L S S+ P L P ++ +PPP
Sbjct: 605 LALAPGPPPPPSRSPSSTLSGPD--LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 662
Query: 621 LPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQS---------SQVPEKPRPALL 671
L A G PP +G P P PPA+ S ++ PE PA
Sbjct: 663 LAACHPAAWSRGPAPPLAFRGAPG--APLPWPPATGPGSADGLCTIYETEGPESATPA-- 718
Query: 672 PTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSS 716
P + G +P T+ AG S LP + +
Sbjct: 719 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQA 763
Score = 47.4 bits (111), Expect = 2e-04
Identities = 120/491 (24%), Positives = 165/491 (33%), Gaps = 84/491 (17%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPAL---PATVPPPGMPPPVMPPSLPTSVP--------- 574
PP P PPPV P +L A+ P G+ +P S P + P
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 575 -PPGMPPS---------LSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPV-----M 619
P PP+ + P PV P S P L L +A V
Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148
Query: 620 PLPPLSSAT---------PPPGIPPPGVPQGIPPQLTAAPVP-PASSSQSSQVPEKPRPA 669
P S+ + P PG P P + + T +P PA S++ E PR +
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 670 LLPTPVSFGSAPPTTYHPPL----QSAGPSEQVNSKAPLSKSALPYSSFS----SDQGLG 721
VS S TT P SAG Q + LS SA P SS + S +G
Sbjct: 209 -----VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Query: 722 ESSAAPSQP----ITAVKDMPVR-------------SGGLLPDPPRSSYLESPRGPRFDG 764
+ A PSQP + A++ V S L P S+ L+S P
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323
Query: 765 PRRFEDLGSRCEGPRPKGPRFEGNRPD-GPRPRYEGHPAEGTKSKWGMIPRGPASQFYIT 823
L + P P P P P P + G P A+ ++
Sbjct: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS-PTLQATHSFL- 381
Query: 824 PSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAA 883
PS LSP + P + P PA Q P S P S PLA T S Q N
Sbjct: 382 PSPPLSPLATPPP-QAP-PALALPPLQAPPS--PPASPPLSPLA-TPSPQAPN------- 429
Query: 884 FSIAADVKDVKAAQSNENLSDSQQEPPKS-EVSEGPVEPSNWDQNVQSMETQIDKAQAVT 942
++A + + + PP S VS PS ++ + Q+ + +
Sbjct: 430 -ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488
Query: 943 QPVPLANKPVP 953
P+ + P P
Sbjct: 489 PPMSPSATPPP 499
Score = 42.4 bits (98), Expect = 0.005
Identities = 63/264 (23%), Positives = 91/264 (34%), Gaps = 27/264 (10%)
Query: 611 SSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPAL 670
++ AP + P PP S PPP P G + P+ + + P
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 671 LPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAP--S 728
PT + S+ PP G +AP +K+ P S + G + P
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRG------ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 729 QPITAVKDMPVRSGGLLPDPPRSSYLESPR----GPRFDGP-----RRFEDLGSRCEGPR 779
+ + + V G P RS+ R GP P RR G+ PR
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191
Query: 780 PKGPRFEGNRPDGPRPRY---------EGHPAEGTKSKWGMIPRGPASQFYITPSTSL-S 829
P +GPR E PA + G + PAS+ + +T L S
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 830 PRQSGPQWKGPKPAFGQQHQQQPK 853
P +SGP +G A Q +PK
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPK 275
Score = 42.0 bits (97), Expect = 0.006
Identities = 38/147 (25%), Positives = 47/147 (31%), Gaps = 21/147 (14%)
Query: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPP-------L 1555
P PP P P PP P + P P+ P PPP L
Sbjct: 343 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402
Query: 1556 P----PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPP- 1610
P PP P P S + + + L + F + AP PP
Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAV------HLLQAPFSPPPSPPVQAPFSPPA 456
Query: 1611 -PPVHSSIPPPGPVP--MGMPPMSKPP 1634
PPV S PP P + PP+ PP
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPP 483
Score = 41.6 bits (96), Expect = 0.008
Identities = 50/200 (25%), Positives = 65/200 (32%), Gaps = 43/200 (21%)
Query: 1474 QKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPA 1533
Q + P PP + +++ P PPP + PP + KPP P APPA
Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-APPLQLAKPP-----PQAPPA 522
Query: 1534 RSSVPVTRPPVPIPPPP-----------PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGL 1582
++ P+ P P P P PL PPP P +A
Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL----------- 571
Query: 1583 WDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIP------PPGPVPMGMPPMSKPPPV 1636
Q S S T P P P P S P PGP P PP P
Sbjct: 572 ------QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP---PPSRSPSST 622
Query: 1637 QQTVDYGHGRDISTNKVEQI 1656
D +T+ E++
Sbjct: 623 LSGPDLAGHSSSATSTPEEL 642
Score = 37.7 bits (86), Expect = 0.12
Identities = 71/339 (20%), Positives = 112/339 (33%), Gaps = 69/339 (20%)
Query: 101 QPPPPPMPPPP---------GPALSYQKQQQYKHQ--------MLHHQRDGPPGLVPMEL 143
+PP P PPPP G A + ++ + R GP
Sbjct: 28 RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87
Query: 144 ESPPESPPVP-PGSYMPPSQSYMPPPQPPPSYYPPTSSQPYL-----------PPAQPSP 191
+P PP G PP+++ P P P T+ L A+
Sbjct: 88 RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 192 SQSPPSQSYLA--------PTPSYSSSSSSSQSYLSHSQSYL--PSSQASPSRPSQGHSK 241
+++P + A PTP S + + +S + ++ L P+ A P P++G K
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 207
Query: 242 SQLLA------PPPPSA------------PPGNKTTVQQEPLESGAKNKSTEQQQAAPEP 283
S A P P+A P + PL S A++ + +
Sbjct: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267
Query: 284 DPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVP 343
PS P+ Q R ++ ++ G +A +P + P P
Sbjct: 268 HPSQPKPKGLQA--LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325
Query: 344 ESPS-----SEEPPLPPPNEEVPP-----PLPPEEPQSE 372
S S + PL PP+ PP P PP P S+
Sbjct: 326 HSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364
Score = 37.7 bits (86), Expect = 0.12
Identities = 41/174 (23%), Positives = 55/174 (31%), Gaps = 32/174 (18%)
Query: 1490 PPQESRLQNTSSRPGMYP-------PPGSYRPPPPMGKP----PGSIVRPSAPPARSSVP 1538
PP ++ +S PG P P PPP P P V PS P + +
Sbjct: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
Query: 1539 VTRPPVP---------------IPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
RPP P P PPPPP P + P + +
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645
Query: 1584 DTNDEQGLNSEFKSETAAIPSAPVL----PPPPVHSSIPPPGPVPMGMPPMSKP 1633
D+ E G + + P P PP+ P P+P PP + P
Sbjct: 646 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP--WPPATGP 697
Score = 35.8 bits (81), Expect = 0.46
Identities = 38/149 (25%), Positives = 49/149 (32%), Gaps = 21/149 (14%)
Query: 1501 SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPP- 1559
+ P P G PP PP P+ P SS T P PP LP P
Sbjct: 267 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH 326
Query: 1560 ------------PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPV 1607
P+ P SA + + T Q S A S
Sbjct: 327 SSSLTCQLATPLPLAPPSPSAPPSLQ----TLPSPPATPPSQATTSLGSPTLQATHS--F 380
Query: 1608 LPPPPVH--SSIPPPGPVPMGMPPMSKPP 1634
LP PP+ ++ PP P + +PP+ PP
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPP 409
Score = 33.9 bits (76), Expect = 1.8
Identities = 38/127 (29%), Positives = 48/127 (37%), Gaps = 19/127 (14%)
Query: 1066 EDSREKMNRGEGSRDR-----GLVRP---GSSREKVPGGLQGSQDRGAAGSRERGP-PRR 1116
++ R+K G +R GL+ P GS R P + GAAG+ R P R
Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
Query: 1117 AG----------SQERGPLRRAGSRERIPPRRAGSRERGPPRGPGSRERGLGRSDFGRDR 1166
AG + GP R AG+ R P R + RG P S GR
Sbjct: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
Query: 1167 GPFRPEP 1173
G RP P
Sbjct: 122 GTTRPGP 128
Score = 32.3 bits (72), Expect = 5.1
Identities = 28/89 (31%), Positives = 34/89 (38%), Gaps = 32/89 (35%)
Query: 1508 PPGSYRPPPP--------------MGKPP---------GSIVRPSAP---PARSSVPVTR 1541
PPGS RPPPP +G+ P G+ + SAP P RS+ +R
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSR 88
Query: 1542 PPVPIPPP------PPPPPLPPPPPVIKP 1564
P PP PP P PV P
Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVSSP 117
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 108 bits (270), Expect = 6e-23
Identities = 109/345 (31%), Positives = 127/345 (36%), Gaps = 60/345 (17%)
Query: 517 PPPFVPYSQMPPPL----PTMPPPVLPPSLPPPV--------MPPALPATVPPPGMPPPV 564
PPP P Q PPP P PPP P PPP PP P PP G P
Sbjct: 73 PPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130
Query: 565 MPPSLPTSVPPPGMPPSLS-SAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPP 623
PP PPPG P G P PPP GPPP S SS +PP PP
Sbjct: 131 GPP------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP 184
Query: 624 LSSATPPPGIPPP-GVPQGIPPQ---LTAAPVPPA----------SSSQSSQVP------ 663
P G PPP G PQG PPQ P PP + SQS++ P
Sbjct: 185 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQG 244
Query: 664 -----------EKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYS 712
P P P G P PP + GP Q SK+ S+S
Sbjct: 245 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKP 304
Query: 713 SFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLG 772
QG G P P + P + G PP P+GP G +
Sbjct: 305 QGPPPQG-GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGGSK--SRS 358
Query: 773 SRCEGPRPKG-PRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGP 816
+R +P+G P+ EGN P GP P G+P + G P+GP
Sbjct: 359 ARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ-PQGP 402
Score = 106 bits (265), Expect = 2e-22
Identities = 117/390 (30%), Positives = 142/390 (36%), Gaps = 63/390 (16%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPV--LPPSLPPPVMPPALPATVPPPG--MPPPVMPP 567
GN PP PP P PPP P PPP PP P PP G P PP
Sbjct: 44 GNKPQGPP------SPPGKPQGPPPQGGNQPQGPPP--PPGKPQGPPPQGGNKPQGPPPP 95
Query: 568 SLPTSVPPPGMPPSLSSAGPP--PVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLS 625
P PP G S S PP P PPP P PPP PPP
Sbjct: 96 GKPQGPPPQG-DKSRSPRSPPGKPQGPPPQ--GGNQPQGPPPPPGKPQGPPP-------Q 145
Query: 626 SATPPPGIPPPGVPQGIPPQ------LTAAPV-----PPASSSQSSQVPEKPRPALLPTP 674
P G PPPG PQG PPQ + +P PP Q P P P P
Sbjct: 146 GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP-PGKPQGP 204
Query: 675 VSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAV 734
G P PP + GP Q ++K+ ++S QG G P P
Sbjct: 205 PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG-GNQPQGPPPPPGKP 263
Query: 735 KDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGS---RCEGPRPKGPRFEGNRPD 791
+ P + G PP P+GP G + S + +GP P+G GN+P
Sbjct: 264 QGPPPQGGNKPQGPPPPG---KPQGPPPQGGSKSRSSRSPPGKPQGPPPQG----GNQPQ 316
Query: 792 GPRP---RYEGHPAEGTKSKWGM----IPRGPASQFYITPSTSLSP---RQSGPQWKG-- 839
GP P + +G P +G G P+GP Q ++ SP Q PQ +G
Sbjct: 317 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNN 376
Query: 840 ----PKPAFGQQHQQQPKSQAEPLSGNKEP 865
P PA G Q Q +P + P
Sbjct: 377 PQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 406
Score = 94.0 bits (232), Expect = 1e-18
Identities = 107/375 (28%), Positives = 137/375 (36%), Gaps = 45/375 (12%)
Query: 552 PATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLS 611
P PP G P PPS P P G PP P PPP GPPP +
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGK--PQGPPPQ--GGNQPQGPPPPPGKPQGPPP--QGGNKP 89
Query: 612 STAPPPVMPL--PPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPA 669
PPP P PP + P PPG PQG PPQ P P P P
Sbjct: 90 QGPPPPGKPQGPPPQGDKSRSPR-SPPGKPQGPPPQGGNQPQGP-----------PPPPG 137
Query: 670 LLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQ 729
P G P PP + GP Q ++K+ S+S QG G P
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG-GNQPQGPPP 196
Query: 730 PITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGS---RCEGPRPKGPRFE 786
P + P + G PP P+GP G + + S + +GP P+G
Sbjct: 197 PPGKPQGPPPQGGNKPQGPPPPG---KPQGPPPQGDNKSQSARSPPGKPQGPPPQG---- 249
Query: 787 GNRPDGPRP---RYEGHPAEGTKSKWGM----IPRGPASQFYITPSTSLSPRQSGPQWKG 839
GN+P GP P + +G P +G G P+GP Q S S S R + +G
Sbjct: 250 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ---GGSKSRSSRSPPGKPQG 306
Query: 840 PKPAFGQQHQQQP----KSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKA 895
P P G Q Q P K Q P G +P + + Q + S +A K
Sbjct: 307 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366
Query: 896 AQSNENLSDSQQEPP 910
+ ++ Q PP
Sbjct: 367 QGPPQQEGNNPQGPP 381
Score = 86.7 bits (213), Expect = 2e-16
Identities = 102/397 (25%), Positives = 133/397 (33%), Gaps = 65/397 (16%)
Query: 10 GSSHYPPP-----PVPPPPPVALPEASPGPGYSSSTTPAAPSS-SGFMSFREQHLAQLQQ 63
G PPP P PPPP P+ P G + P P G ++ +
Sbjct: 55 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 114
Query: 64 LQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGP--------AL 115
+ Q QP PPPP P P GG PPPP P P P +
Sbjct: 115 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSR 174
Query: 116 SYQKQQQYKHQMLHHQRDGPPGLV------PMELESPPESPPVPPGSYMPP------SQS 163
S + Q +Q GPP P + + P+ PP P PP SQS
Sbjct: 175 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQS 234
Query: 164 YMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQS 223
PP P P +QP PP P Q PP Q P Q S
Sbjct: 235 ARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG--GNKPQGPPPPGKPQGPPPQGGS 292
Query: 224 YLPSSQASPSRPS----QGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQA 279
SS++ P +P QG ++ Q PPPP P Q P + G K Q
Sbjct: 293 KSRSSRSPPGKPQGPPPQGGNQPQ--GPPPPPGKP------QGPPPQGGNK-----PQGP 339
Query: 280 APEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPAT 339
P P PQ + R+ PG +GP ++E P
Sbjct: 340 PPPGKPQGPPPQGGSK-----------SRSARSPPGKPQGPP---------QQEGNNPQG 379
Query: 340 SQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEE 376
P + ++P PP + PP PP+ + P +
Sbjct: 380 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416
Score = 80.1 bits (196), Expect = 2e-14
Identities = 94/329 (28%), Positives = 112/329 (34%), Gaps = 73/329 (22%)
Query: 77 QPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPP 136
+P P PP P P GG PPPPP P P K Q GPP
Sbjct: 46 KPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ------------GPP 93
Query: 137 GLVPMELESPP------ESPPVPPGSYM-PPSQSYMPPPQPPPSYYPPTSSQPYLPPAQP 189
P + + PP SP PPG PP Q P PPP PP Q P
Sbjct: 94 --PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGN 148
Query: 190 SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP-----------SRPSQG 238
P PP P P + S SS+S Q P P P QG
Sbjct: 149 KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 208
Query: 239 HSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWY 298
+K Q PPPP P G P + K++S P+ P PQ
Sbjct: 209 GNKPQ--GPPPPGKPQG-------PPPQGDNKSQSARSPPGKPQGPP----PQGGN---- 251
Query: 299 RQHLLSLQQRTKVHLPGHKKGPV-----VAKDTPEPVKEEVTVPATSQVPESPSSEEPP- 352
Q + PG +GP + P P K + P +S SS PP
Sbjct: 252 -------QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS--KSRSSRSPPG 302
Query: 353 ---LPPP---NEEVPPPLPPEEPQSEDPE 375
PPP N+ PP PP +PQ P+
Sbjct: 303 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 331
Score = 68.6 bits (166), Expect = 6e-11
Identities = 66/189 (34%), Positives = 72/189 (38%), Gaps = 38/189 (20%)
Query: 524 SQMPPPLPTMPPPV--LPPSLPPPVMPPALPATVPPPG--MPPPVMPPSLPTSVPPPGMP 579
++ PP P PPP P PPP PP P PP G P PP P PP G
Sbjct: 235 ARSPPGKPQGPPPQGGNQPQGPPP--PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 292
Query: 580 PSLSSA-------GPPPV-------LPPPSLSSAGPPPVL------PPPSLSSTAPPPVM 619
S SS GPPP PPP GPPP PPP PPP
Sbjct: 293 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352
Query: 620 PLPPLSSATPPPGIPPPGVPQGIPPQ---LTAAPVPPASSS-QSSQVPEKPRPALLPTPV 675
S+ + PPG PQG P Q P PPA + Q Q P +P P P
Sbjct: 353 GSKSRSARS------PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 406
Query: 676 SFG--SAPP 682
G S PP
Sbjct: 407 QGGRPSRPP 415
Score = 67.4 bits (163), Expect = 1e-10
Identities = 56/167 (33%), Positives = 61/167 (36%), Gaps = 27/167 (16%)
Query: 517 PPPFVPYSQMPPPL----PTMPPPVLPPSLPPPV---------MPPALPATVPPPGMPPP 563
PPP P Q PPP P PPP P PPP PP P PP G P
Sbjct: 258 PPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP 315
Query: 564 VMPPSLPTSVPPPGMPPSLS-SAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLP 622
PP PPPG P G P PPP GPPP S S+ +PP P
Sbjct: 316 QGPP------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Query: 623 PLSSAT-----PPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPE 664
P PPP P PQ P P P + S+ P+
Sbjct: 370 PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416
Score = 62.0 bits (149), Expect = 6e-09
Identities = 116/492 (23%), Positives = 168/492 (34%), Gaps = 111/492 (22%)
Query: 713 SFSSDQGLGESSAAPSQPITAV---KDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFE 769
+ SS Q L E + P + P + G PP S P+GP G
Sbjct: 12 ALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPP--SPPGKPQGPPPQG----- 64
Query: 770 DLGSRCEGP-----RPKGPRFEG-NRPDGPRP--RYEGHPAEGTKSKWGMIPRGPASQFY 821
G++ +GP +P+GP +G N+P GP P + +G P +G KS+ PR P +
Sbjct: 65 --GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR---SPRSPPGK-- 117
Query: 822 ITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQS 881
P Q G Q +GP P G K Q P G +P + + Q
Sbjct: 118 ----PQGPPPQGGNQPQGPPPPPG-------KPQGPPPQGGNKPQGPPPPGKPQGPPPQG 166
Query: 882 AAFSIAADVKDVKAAQSNENLSDSQQEPPKS-EVSEGPVEPSNWDQNVQSMETQIDKAQA 940
D K+ S Q PP+ +GP P Q Q
Sbjct: 167 ----------DNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG--------PPPQG 208
Query: 941 VTQPVPLANKPVPAQSTFPSKTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGL 1000
+P P P + P G + +A + KP G P NQ +G
Sbjct: 209 GNKP---QGPPPPGKPQGPPPQGDNKSQSARSPPG-------KPQGP--PPQGGNQPQGP 256
Query: 1001 PRPDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDK 1060
P P + GN + +G G+ Q G
Sbjct: 257 PPPPGKPQGPPPQGGN---------------KPQGPPPPGKPQGPPPQGG---------- 291
Query: 1061 MMGRREDSREKMNRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQ 1120
+ SR + +G +G +P PG QG +G G++ +GPP Q
Sbjct: 292 --SKSRSSRSPPGKPQGPPPQGGNQP-QGPPPPPGKPQGPPPQG--GNKPQGPPPPGKPQ 346
Query: 1121 ERGPLRRAGSRERI----------PPRRAGSRERGPPRGPGSRERGLGRSDFGRDRGPFR 1170
GP + GS+ R PP++ G+ +GPP G + G+ +GP
Sbjct: 347 --GPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP-- 402
Query: 1171 PEPGDGGEKMYP 1182
P P GG P
Sbjct: 403 PRPPQGGRPSRP 414
Score = 60.8 bits (146), Expect = 1e-08
Identities = 58/178 (32%), Positives = 68/178 (38%), Gaps = 35/178 (19%)
Query: 1480 GSEPQMADHLPPQESRLQNT----SSRPGMYPPPGSYRPPPPMG-------KPPGSIVRP 1528
G++PQ PP + Q ++P PPPG + PPP G PPG P
Sbjct: 65 GNQPQGP---PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 121
Query: 1529 SAPPARSSVPVTRPPVPIPPPPPPP-----PLPPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
PP + P PP P P PPP P PPPP KPQ + + S
Sbjct: 122 --PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPPQGDNKSRSS----- 173
Query: 1584 DTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP--GPVPMGMPPMSKP--PPVQ 1637
G + P P PPPP PPP G P G PP KP PP Q
Sbjct: 174 --RSPPGKPQGPPPQGGNQPQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 227
Score = 60.1 bits (144), Expect = 2e-08
Identities = 71/271 (26%), Positives = 96/271 (35%), Gaps = 41/271 (15%)
Query: 120 QQQYKHQMLHHQRDGPP--GLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPP 177
Q++ + + + PP G P SPP P PP Q PPP P P
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 84
Query: 178 TSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSR--P 235
++P PP P Q PP Q + +P +Q P + P
Sbjct: 85 GGNKPQGPP-PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 143
Query: 236 SQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQ 295
QG +K Q PPPP P G P + K++S+ P+ P PQ
Sbjct: 144 PQGGNKPQ--GPPPPGKPQG-------PPPQGDNKSRSSRSPPGKPQGPP----PQGGN- 189
Query: 296 YWYRQHLLSLQQRTKVHLPGHKKGPV-----VAKDTPEPVKEEVTVPA---TSQVPESPS 347
Q + PG +GP + P P K + P SQ SP
Sbjct: 190 ----------QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPP 239
Query: 348 SEEPPLPPP---NEEVPPPLPPEEPQSEDPE 375
+P PPP N+ PP PP +PQ P+
Sbjct: 240 G-KPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269
Score = 58.9 bits (141), Expect = 5e-08
Identities = 66/247 (26%), Positives = 81/247 (32%), Gaps = 54/247 (21%)
Query: 134 GPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQ 193
G P P + + P+ PP PPG PQ PP P +QP PP P Q
Sbjct: 34 GNPQGAPPQGGNKPQGPPSPPGK-----------PQGPP---PQGGNQPQGPPPPPGKPQ 79
Query: 194 SPPSQSY---LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPP 250
PP Q P P Q S S P P P QG ++ Q PPPP
Sbjct: 80 GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP--PPQGGNQPQ--GPPPP 135
Query: 251 SAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTK 310
P Q P + G K Q P P PQ + R+
Sbjct: 136 PGKP------QGPPPQGGNK-----PQGPPPPGKPQGPPPQGDNK-----------SRSS 173
Query: 311 VHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQ 370
PG +GP P + P P P + P P + P PP +PQ
Sbjct: 174 RSPPGKPQGP------PPQGGNQPQGP-----PPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222
Query: 371 SEDPEED 377
P+ D
Sbjct: 223 GPPPQGD 229
Score = 56.2 bits (134), Expect = 3e-07
Identities = 60/185 (32%), Positives = 71/185 (38%), Gaps = 48/185 (25%)
Query: 1480 GSEPQMADHLPPQESRLQNT----SSRPGMYPPPGSYRPPPPMG--------KPPGSIVR 1527
G++PQ PP + Q ++P PPPG + PPP G PPG +
Sbjct: 188 GNQPQGP---PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPG---K 241
Query: 1528 PSAPPARSSVPVTRPPVPIPPPPPPPPLPP---------PPPVIKPQTSAVE--QERWDE 1576
P PP + +P P PPPP P PP PPP KPQ + +
Sbjct: 242 PQGPPPQGG---NQPQGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS 297
Query: 1577 DSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP--GPVPMGMPPMSKP- 1633
S G QG N P P PPPP PPP G P G PP KP
Sbjct: 298 RSPPGKPQGPPPQGGNQ---------PQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQ 346
Query: 1634 -PPVQ 1637
PP Q
Sbjct: 347 GPPPQ 351
Score = 55.1 bits (131), Expect = 7e-07
Identities = 55/159 (34%), Positives = 61/159 (38%), Gaps = 31/159 (19%)
Query: 1492 QESRLQNTSSRPGMYPPPGSYRP---PPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548
QE + P PP G +P P P GKP G PP + P PP P P
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQG------PPPQGGNQPQGPPPPPGKP 78
Query: 1549 PPPPP-----PLPPPPPVIKPQTSAVEQER-WDEDSFYGLWDTNDEQGLNSEFKSETAAI 1602
PPP P PPPP KPQ + ++ S G QG N
Sbjct: 79 QGPPPQGGNKPQGPPPPG-KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ--------- 128
Query: 1603 PSAPVLPPPPVHSSIPPP--GPVPMGMPPMSKP--PPVQ 1637
P P PPPP PPP G P G PP KP PP Q
Sbjct: 129 PQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 165
Score = 53.1 bits (126), Expect = 3e-06
Identities = 102/442 (23%), Positives = 143/442 (32%), Gaps = 97/442 (21%)
Query: 776 EGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGP 835
+G P+G GN+P GP P G P +G + G P+GP P P
Sbjct: 37 QGAPPQG----GNKPQGP-PSPPGKP-QGPPPQGGNQPQGPP------------PPPGKP 78
Query: 836 QWKGPKPAFGQQHQQQP---KSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKD 892
Q GP P G + Q P K Q P G+K + + + Q
Sbjct: 79 Q--GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136
Query: 893 VKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPV 952
K + Q PP +GP P D +S + K Q P P
Sbjct: 137 GKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDNKSRSSRSPPGKPQG---PPPQGGNQP 191
Query: 953 PAQSTFPSKTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPRPDNRDNRLEG 1012
P K G P G P K P DN+ +
Sbjct: 192 QGPPPPPGKPQGPP-----------------PQGGNKPQGPPPPGKPQGPPPQGDNKSQS 234
Query: 1013 NRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAISRGPGLVKQEDFRDKMMGRREDSREKM 1072
R +GP + Q PG K G
Sbjct: 235 ARSPPGKPQGPPPQ-----------GGNQPQGPPPPPG---------KPQGPPPQG---- 270
Query: 1073 NRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRE 1132
G++ +G PG + P G S+ + + +GPP + G+Q +GP G +
Sbjct: 271 ----GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG-KP 325
Query: 1133 RIPPRRAGSRERGP-----PRGP----GSRERGLGRSDFGRDRGPFR--------PEPGD 1175
+ PP + G++ +GP P+GP GS+ R RS G+ +GP + P P
Sbjct: 326 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS-ARSPPGKPQGPPQQEGNNPQGPPPPA 384
Query: 1176 GGEKMYPY-----HRDEPPRAP 1192
GG P PPR P
Sbjct: 385 GGNPQQPQAPPAGQPQGPPRPP 406
Score = 51.2 bits (121), Expect = 1e-05
Identities = 52/174 (29%), Positives = 66/174 (37%), Gaps = 40/174 (22%)
Query: 1480 GSEPQMADHLPPQESRLQNT----SSRPGMYPPPGSYRPPPPMG--------KPPGSIVR 1527
G++PQ PP + Q ++P PPPG + PPP G PPG +
Sbjct: 250 GNQPQGP---PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG---K 303
Query: 1528 PSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTND 1587
P PP + +P P PPPP P PPP KPQ G
Sbjct: 304 PQGPPPQGG---NQPQGP-PPPPGKPQGPPPQGGNKPQ---------------GPPPPGK 344
Query: 1588 EQGLNSEFKSETAAIPSAPVLPP-PPVHSSIPPPGPVPM--GMPPMSKPPPVQQ 1638
QG + S++ + S P P PP P GP P G P + PP Q
Sbjct: 345 PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 398
Score = 50.4 bits (119), Expect = 2e-05
Identities = 40/135 (29%), Positives = 64/135 (47%), Gaps = 17/135 (12%)
Query: 1077 GSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPP 1136
G++ +G PG + P G SQ + + +GPP + G+Q +GP G + + PP
Sbjct: 209 GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPG-KPQGPP 267
Query: 1137 RRAGSRERGP-----PRGP----GSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDE 1187
+ G++ +GP P+GP GS+ R RS G+ +GP P GG + P
Sbjct: 268 PQGGNKPQGPPPPGKPQGPPPQGGSKSRS-SRSPPGKPQGP----PPQGGNQ--PQGPPP 320
Query: 1188 PPRAPWNHGEERGHE 1202
PP P + G++
Sbjct: 321 PPGKPQGPPPQGGNK 335
Score = 48.1 bits (113), Expect = 9e-05
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 15/134 (11%)
Query: 1077 GSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPP 1136
G++ +G PG + P G S+ + + +GPP + G+Q +GP G + + PP
Sbjct: 147 GNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG-KPQGPP 205
Query: 1137 RRAGSRERGP-----PRGP---GSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEP 1188
+ G++ +GP P+GP G + RS G+ +GP P GG + P P
Sbjct: 206 PQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP----PPQGGNQ--PQGPPPP 259
Query: 1189 PRAPWNHGEERGHE 1202
P P + G++
Sbjct: 260 PGKPQGPPPQGGNK 273
Score = 47.4 bits (111), Expect = 2e-04
Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 16/134 (11%)
Query: 1077 GSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPP 1136
G++ +G PG + P G + R G + +GPP + G+Q +GP G + + PP
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG-KPQGPPPQGGNQPQGPPPPPG-KPQGPP 143
Query: 1137 RRAGSRERGP-----PRGP---GSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEP 1188
+ G++ +GP P+GP G + RS G+ +GP P GG + P P
Sbjct: 144 PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP----PPQGGNQ--PQGPPPP 197
Query: 1189 PRAPWNHGEERGHE 1202
P P + G++
Sbjct: 198 PGKPQGPPPQGGNK 211
Score = 44.7 bits (104), Expect = 0.001
Identities = 37/112 (33%), Positives = 42/112 (37%), Gaps = 15/112 (13%)
Query: 512 GNMSMPPPFVP-YSQMPPP----LPTMPPPVLPPSLPPPVMPPALPATVPPPGMP--PPV 564
GN PP P Q PPP P PPP P PPP + PPG P PP
Sbjct: 312 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQ 371
Query: 565 MPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPP 616
+ P PPP + P PP+ GPP PP + PP
Sbjct: 372 QEGNNPQGPPPP------AGGNPQQPQAPPAGQPQGPP--RPPQGGRPSRPP 415
Score = 42.0 bits (97), Expect = 0.006
Identities = 37/143 (25%), Positives = 63/143 (44%), Gaps = 16/143 (11%)
Query: 1068 SREKMNRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRR 1127
S + +N + + G+ + P G Q + + +GPP + G+Q +GP
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPP 74
Query: 1128 AGSRERIPPRRAGSRERGP-----PRGP---GSRERGLGRSDFGRDRGPFRPEPGDGGEK 1179
G + + PP + G++ +GP P+GP G + R RS G+ +GP P GG +
Sbjct: 75 PG-KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS-PRSPPGKPQGP----PPQGGNQ 128
Query: 1180 MYPYHRDEPPRAPWNHGEERGHE 1202
P PP P + G++
Sbjct: 129 --PQGPPPPPGKPQGPPPQGGNK 149
Score = 42.0 bits (97), Expect = 0.006
Identities = 31/98 (31%), Positives = 40/98 (40%), Gaps = 21/98 (21%)
Query: 1480 GSEPQMADHLPPQESRLQNT----SSRPGMYPPPGSYRPPPPMG--------KPPGSIVR 1527
G++PQ PP + Q ++P PPPG + PPP G PPG +
Sbjct: 312 GNQPQGP---PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPG---K 365
Query: 1528 PSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQ 1565
P PP + P P PP P P PP +PQ
Sbjct: 366 PQGPPQQEG---NNPQGPPPPAGGNPQQPQAPPAGQPQ 400
Score = 35.4 bits (80), Expect = 0.61
Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 9/125 (7%)
Query: 1088 SSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPP 1147
SS + + + + +G P + G++ +GP G + + PP + G++ +GPP
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPG-KPQGPPPQGGNQPQGPP 72
Query: 1148 RGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLD 1207
PG + +G + +GP P PG + PR+P G+ +G P
Sbjct: 73 PPPG-KPQGPPPQGGNKPQGP--PPPGKPQGPPPQGDKSRSPRSP--PGKPQGP---PPQ 124
Query: 1208 GRNAP 1212
G N P
Sbjct: 125 GGNQP 129
Score = 34.3 bits (77), Expect = 1.4
Identities = 24/67 (35%), Positives = 29/67 (43%), Gaps = 4/67 (5%)
Query: 1490 PPQE-SRLQNTSSRPGMYPPPGSYRPPPPMGKPP---GSIVRPSAPPARSSVPVTRPPVP 1545
PPQ S+ ++ S PG P P G PP G+ +P APPA RPP
Sbjct: 349 PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 408
Query: 1546 IPPPPPP 1552
P PP
Sbjct: 409 GRPSRPP 415
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 107 bits (267), Expect = 1e-22
Identities = 107/363 (29%), Positives = 136/363 (37%), Gaps = 72/363 (19%)
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPPSL----PPPVMPP------------ALPATVPP 557
+S P P ++ P P P P L PP V PP + P P
Sbjct: 240 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 299
Query: 558 PGMPP-PVMPPSLPTSVPPPGMPPS--LSSAGPPPV------LPPPSLSSAGPPPVLPPP 608
P PP P PPSL T PP PPS +S G P + LP P LS PP PP
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 609 SLS------STAPPPVMPLPPLSSA-----------------TPPPGIP------PPGVP 639
+L+ +PP PL PL++ +PPP P PP P
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 640 QGIPPQLTAAPVPPASSSQSSQVPEKP--RPALLPTPVSFGSAPPTTYHPPLQSAGPSEQ 697
P + PP+ ++ QVP P P + P+ APP PPLQ A P Q
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 698 VN---SKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDM--PVRSGGLL---PDPP 749
+ PL P +SF S++ P P+ PV + LL P PP
Sbjct: 480 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539
Query: 750 RSSYLESPRGPRFDGPRRFEDLGSR-----CEGPRPKGPRFEGNRPDGPRPRYEGHPAEG 804
S L++PR P GP G R GP P R + G P GH +
Sbjct: 540 ASPTLQAPRRPPTPGPDTSVS-GPRLTLALAPGPPPPPSRSPSSTLSG--PDLAGHSSSA 596
Query: 805 TKS 807
T +
Sbjct: 597 TST 599
Score = 103 bits (257), Expect = 2e-21
Identities = 109/359 (30%), Positives = 134/359 (37%), Gaps = 75/359 (20%)
Query: 514 MSMPPPFVPYSQMPPPL-----PTMPPPVLPPSLPPPVMPPALPATV------PPPGMP- 561
++ PPP P + PPL P PP+ P + P P P AL + PPP P
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 409
Query: 562 -----PPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP- 615
PP PP P++ PP PPSL++ PP+ PPS PP PP S S+T P
Sbjct: 410 QAPFSPPASPPVSPSATPPSQAPPSLAA---PPLQVPPS------PPASPPMSPSATPPP 460
Query: 616 --PPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPT 673
PP + PPL A PPP PP P L A P PPAS Q P P +L +
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALA----TPPLQALPSPPASF--PGQAPFSPSASLPMS 514
Query: 674 PVSF--GSAPPTTYHPPLQ------------------SAGPSEQVNSK---------APL 704
P++ APP P LQ + GP V+ P
Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574
Query: 705 SKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLES------PR 758
S P S+ S G SS+A S P GG PP + L + R
Sbjct: 575 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 634
Query: 759 GPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPA 817
GP P F P P P DG YE E G + GP+
Sbjct: 635 GPA--PPLAFRGAPG---APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS 688
Score = 89.7 bits (221), Expect = 3e-17
Identities = 86/298 (28%), Positives = 103/298 (34%), Gaps = 28/298 (9%)
Query: 3 PNWGRYGGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQ 62
P G S P P PP P A P P + PA P S S
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLP-----SPPATPPSQATTSLGSP------ 333
Query: 63 QLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPAL--SYQKQ 120
LQ H L P PPP PP +P PP PP PP P S Q
Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ----APPSPPASPPLSPLATPSPQAP 389
Query: 121 QQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPG----SYMPPSQSYMP---PPQPPPS 173
+L PP SPP SPPV P S PPS + P PP PP S
Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449
Query: 174 YYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS 233
PP S PP P P +PP Q P + + ++ L + P +P
Sbjct: 450 --PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ--APF 505
Query: 234 RPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQ 291
PS S L PPP + P +Q P + ++ P PD S P+
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563
Score = 72.4 bits (176), Expect = 4e-12
Identities = 80/268 (29%), Positives = 101/268 (37%), Gaps = 44/268 (16%)
Query: 513 NMSMPPPFVPYSQMPPPLPTMPPPVLPP--SLPPPVMPPALPATVPPPGMPPPVMPPSLP 570
+++ PP VP S PP P M P PP + PP PP L PPP PP + P L
Sbjct: 434 SLAAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPP-LQLAKPPPQAPPALATPPLQ 490
Query: 571 TSVPPPGMPPSLSSAGPPPVLPPPSLSSAGP--PPVLPPPSLSSTAPPPVMPL------P 622
PP P + P LP L++ P PPVL P L PP P P
Sbjct: 491 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 550
Query: 623 PL----SSATPP-------PGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALL 671
P +S + P PG PPP P P + P SS ++ PE+ R
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPPPP--PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608
Query: 672 PTPVSFGSAPP-----TTYHPPLQSAGPSEQVNSK----APLSKSALPYSSFSSDQGL-- 720
++PP HP S GP+ + + APL P + S GL
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP--PATGPGSADGLCT 666
Query: 721 -----GESSAAPSQPITAVKDMPVRSGG 743
G SA P+ P SGG
Sbjct: 667 IYETEGPESATPAPGALDPGPSPGTSGG 694
Score = 69.7 bits (169), Expect = 3e-11
Identities = 73/264 (27%), Positives = 97/264 (36%), Gaps = 49/264 (18%)
Query: 511 MGNMSMPPPFVPYSQMPPPLP-TMPPPVLPPSL--PPPVMPPALPATVP--PPGMPPPVM 565
M + PPP P PPL PPP PP+L PP P+ PA+ P P P +
Sbjct: 452 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 511
Query: 566 PPSLPTSVPPPGMPPSLSS---AGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLP 622
P S P + PPP PP L++ PP P+L + PP P P S + P + L
Sbjct: 512 PMS-PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT-PGPDTSVSGPRLTLALA 569
Query: 623 PLSSATPPPGIPPPGVPQG------------IPPQLTAAPVPPASSSQSSQVPEKPRPAL 670
P PPP P G P +L P + +S P+ A
Sbjct: 570 P--GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 627
Query: 671 LPTPVSFGSAPPTTYH---------PP-------------LQSAGPSEQVNSKAPLSKSA 708
P S G APP + PP ++ GP + L
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687
Query: 709 LPYSS---FSSDQGLGESSAAPSQ 729
P +S ++ G G SS +P Q
Sbjct: 688 SPGTSGGKAAAGAGAGASSRSPKQ 711
Score = 68.2 bits (165), Expect = 8e-11
Identities = 109/424 (25%), Positives = 140/424 (33%), Gaps = 94/424 (22%)
Query: 9 GGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAP-SSSGFMSFREQHLAQLQQLQQM 67
G PP P PV+ PG +S TT P G E+ +A+ + +
Sbjct: 89 GRGERAPPAKNTSPGPVS------SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 142
Query: 68 HQKQMQCVLQPHHLPPPPLPPPPVMP------GGGYGDWQPPPP--PMPPPPGPALSYQK 119
+ + + P P P P M G G +P P P PP GP S
Sbjct: 143 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202
Query: 120 QQQYK----HQMLHHQRDGPPGLV----------PMELESPPESPPVPPGSYMPPSQSYM 165
++ + GL L SP S P G+ P+
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262
Query: 166 PPPQP-----PPSYYPPT----------SSQPYLPP---AQPSPSQSPPSQSYLAP--TP 205
P P+ PP PP SS P P A PSPS P Q+ +P TP
Sbjct: 263 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATP 322
Query: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPL 265
+++S L + S+LPS SP LA PPP APP Q P
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSP------------LATPPPQAPPALALPPLQAP- 369
Query: 266 ESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLL----SLQQRTKVHLPGHKKG-- 319
A+P P TP Q HLL S V P
Sbjct: 370 ---------PSPPASPPLSPLA-TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 320 PVVAKDTPE----------PVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPP----PLP 365
PV TP P++ + PA+ P SPS+ PP PP PP P
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQLAKPP 477
Query: 366 PEEP 369
P+ P
Sbjct: 478 PQAP 481
Score = 66.2 bits (160), Expect = 3e-10
Identities = 90/362 (24%), Positives = 114/362 (31%), Gaps = 83/362 (22%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
P P P PP P S STT +P++ + + LQ+ + +
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA-------RRRPSAGGGLQRPASRSLSS 235
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134
P P P P P P P P G Q
Sbjct: 236 SATPLSSPARSGPSARGTPRA------PAHPSQPKPKGL-----------------QALR 272
Query: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS 194
PP + P ++ P P+ PS S P P PPS PSP +
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL-----------QTLPSPPAT 321
Query: 195 PPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPP 254
PPSQ +++S L + S+LPS SP LA PPP APP
Sbjct: 322 PPSQ----------ATTSLGSPTLQATHSFLPSPPLSP------------LATPPPQAPP 359
Query: 255 GNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLP 314
Q P A+P P TP Q HLL +
Sbjct: 360 ALALPPLQAP----------PSPPASPPLSP-LATPSPQAPNALAVHLL------QAPFS 402
Query: 315 GHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374
PV A +P P V+ AT PS PPL P PP PP P + P
Sbjct: 403 PPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPS--PPASPPMSPSATPP 459
Query: 375 EE 376
+
Sbjct: 460 PQ 461
Score = 66.2 bits (160), Expect = 3e-10
Identities = 85/312 (27%), Positives = 110/312 (35%), Gaps = 62/312 (19%)
Query: 14 YPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQ 73
+ PPP PP P ASP S++ AP S LQ
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA-----------APPLQVPPSPPAS 449
Query: 74 CVLQPHHLPPPPLPPPPVMPGGGYGDWQPPP--------PPMPPPPGPALSYQKQQQYKH 125
+ P PPP PPP P +PPP PP+ P P S+ Q +
Sbjct: 450 PPMSPSATPPPQAPPPLAAPPLQLA--KPPPQAPPALATPPLQALPSPPASFPGQAPFS- 506
Query: 126 QMLHHQRDGPPGLVPME--LESPPESPPV--------PPGSYMPPSQSYMPPPQPPPSYY 175
P +PM PP++PPV PP PP+ + P+ PP+
Sbjct: 507 ---------PSASLPMSPLATPPPQAPPVLAAPLLQVPPS---PPASPTLQAPRRPPTPG 554
Query: 176 PPTS-SQPYL-----PPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQ 229
P TS S P L P P PS+SP S +SSS++S+ L S P
Sbjct: 555 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG-PEGG 613
Query: 230 ASPSRPSQG-----HSKSQLLAPPPPSAPPGNKTTVQQEPLESG---AKNKSTEQQQAAP 281
A+ S P H + P PP A G P +G A T + P
Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673
Query: 282 E---PDPSTMTP 290
E P P + P
Sbjct: 674 ESATPAPGALDP 685
Score = 60.1 bits (144), Expect = 2e-08
Identities = 64/208 (30%), Positives = 83/208 (39%), Gaps = 41/208 (19%)
Query: 1481 SEPQMADHLPPQESRLQNTSSRPGMYPP----PGSYRPPPPMGKPPGSIVRPSA-PPARS 1535
S P A PP + +++ P PP P PP P PP S PSA PP ++
Sbjct: 406 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS---PSATPPPQA 462
Query: 1536 SVPVTRPPVPIPPPPP--PPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNS 1593
P+ PP+ + PPP PP L PP P A SF G +
Sbjct: 463 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA---------SFPG----------QA 503
Query: 1594 EFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKV 1653
F S +A++P +P+ PPP PP P+ P S PP T+ R T
Sbjct: 504 PF-SPSASLPMSPLATPPP---QAPPVLAAPLLQVPPS--PPASPTLQ--APRRPPTPGP 555
Query: 1654 EQIPYGERITLR----PDPLPERSTFET 1677
+ G R+TL P P P RS T
Sbjct: 556 DTSVSGPRLTLALAPGPPPPPSRSPSST 583
Score = 57.4 bits (137), Expect = 1e-07
Identities = 47/168 (27%), Positives = 59/168 (35%), Gaps = 20/168 (11%)
Query: 1474 QKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPP----PGSYRPPPPMGKPPGSIVRPS 1529
Q GS A H L ++ P PP P PP P PP S +
Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384
Query: 1530 APPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQ 1589
+P A +++ V P PPP PP P P P S T Q
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA--------------TPPSQ 430
Query: 1590 GLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPP--MSKPPP 1635
S PS P PP ++ PP P P+ PP ++KPPP
Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478
Score = 55.8 bits (133), Expect = 4e-07
Identities = 90/351 (25%), Positives = 120/351 (34%), Gaps = 72/351 (20%)
Query: 556 PPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVL--PPPSLSSAGPPPVLPPP----- 608
P PG P P M + G+P SA P P P S+SSA P
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 609 --------------SLSSTAPPPVMPL--PPLSSATP-PPGIPPPGVPQGI----PPQLT 647
SLSS+A P P P + TP P P P+G+ PPQ+T
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277
Query: 648 AAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKS 707
PP + + P P P+P SAPP+ SA PS Q P +
Sbjct: 278 ----PPRKDAAPALGPLSSSPLATPSP----SAPPS------PSAPPSLQTLPSPPATPP 323
Query: 708 ALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRR 767
+ +S S S PS P++ + P ++ L PP L++P P P
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP----LQAPPSPPASPPL- 378
Query: 768 FEDLGSRCEGPRPKGPRFEG----NRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYIT 823
S P P+ P P P P P + S P P++ T
Sbjct: 379 -----SPLATPSPQAPNALAVHLLQAPFSPPP---SPPVQAPFSPPASPPVSPSA----T 426
Query: 824 PSTSLSPRQSGPQWKGP---------KPAFGQQHQQQPKSQAEPLSGNKEP 865
P + P + P + P P+ Q P A PL K P
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477
Score = 53.5 bits (127), Expect = 2e-06
Identities = 61/225 (27%), Positives = 79/225 (35%), Gaps = 32/225 (14%)
Query: 511 MGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSL- 569
M ++ PPP P P L P P P+L P PP PG V P L
Sbjct: 513 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT-------PGPDTSVSGPRLT 565
Query: 570 ----PTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVL-----PPPSLSSTAPPPVMP 620
P PPP PS + +GP L S S+ P L P ++ +PPP
Sbjct: 566 LALAPGPPPPPSRSPSSTLSGPD--LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 623
Query: 621 LPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQS---------SQVPEKPRPALL 671
L A G PP +G P P PPA+ S ++ PE PA
Sbjct: 624 LAACHPAAWSRGPAPPLAFRGAPG--APLPWPPATGPGSADGLCTIYETEGPESATPA-- 679
Query: 672 PTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSS 716
P + G +P T+ AG S LP + +
Sbjct: 680 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQA 724
Score = 50.1 bits (118), Expect = 2e-05
Identities = 122/467 (26%), Positives = 161/467 (34%), Gaps = 75/467 (16%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPAL---PATVPPPGMPPPVMPPSLP------TSVPPPG 577
PP P PPPV P +L A+ P G+ +P S P TS PP
Sbjct: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPAS 88
Query: 578 ----MPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPV-----MPLPPLSSAT 628
P + P PV P S P L L +A V P S+ +
Sbjct: 89 GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALS 148
Query: 629 ---------PPPGIPPPGVPQGIPPQLTAAPVP-PASSSQSSQVPEKPRPALLPTPVSFG 678
P PG P P + + T +P PA S++ E PR + VS
Sbjct: 149 AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS-----VSSA 203
Query: 679 SAPPTTYHPPL----QSAGPSEQVNSKAPLSKSALPYSSFS----SDQGLGESSAAPSQP 730
S TT P SAG Q + LS SA P SS + S +G + A PSQP
Sbjct: 204 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP 263
Query: 731 ITAVKDMPVRSGGLLP---DPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEG 787
P L P PPR + GP P S P P P
Sbjct: 264 ------KPKGLQALRPPQVTPPRKDAAPA-LGPLSSSPLA---TPSPSAPPSPSAPPSLQ 313
Query: 788 NRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQ 847
P P P++ T S P A+ ++ PS LSP + P + P PA
Sbjct: 314 TLPSPPAT----PPSQATTSLGS--PTLQATHSFL-PSPPLSPLATPPP-QAP-PALALP 364
Query: 848 HQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQ 907
Q P S P S PLA T S Q N ++A + + +
Sbjct: 365 PLQAPPS--PPASPPLSPLA-TPSPQAPN--------ALAVHLLQAPFSPPPSPPVQAPF 413
Query: 908 EPPKS-EVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVP 953
PP S VS PS ++ + Q+ + + P+ + P P
Sbjct: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460
Score = 49.3 bits (116), Expect = 4e-05
Identities = 66/253 (26%), Positives = 88/253 (34%), Gaps = 31/253 (12%)
Query: 149 SPPVPPGSYMPPSQSYMPPPQPPPSYYPPT-------SSQPYLPPAQPSPS-QSPPSQSY 200
SP + S ++ +P P P PPT SS +PSP+ + PS
Sbjct: 164 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 223
Query: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP---SRPSQGHSKSQLLAPPPPSAPPGNK 257
P+ S SSS+ S ++S PS++ +P + PSQ K PP PP
Sbjct: 224 GLQRPASRSLSSSATPLSSPARSG-PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 282
Query: 258 TTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSL----QQRTKVHL 313
PL S + +P PS T Q SL Q T L
Sbjct: 283 AAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 342
Query: 314 PGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP--PLPPPNEEVP---------- 361
P P+ TP P Q P SP + P PL P+ + P
Sbjct: 343 PSPPLSPLA---TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 399
Query: 362 PPLPPEEPQSEDP 374
P PP P + P
Sbjct: 400 PFSPPPSPPVQAP 412
Score = 43.1 bits (100), Expect = 0.003
Identities = 67/256 (26%), Positives = 94/256 (36%), Gaps = 20/256 (7%)
Query: 611 SSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPP-ASSSQSSQVPEK-PR- 667
++ AP + P PP S PPP P G + P+ A + +PE PR
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 668 -PALLPTPVSFG---SAPP--TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLG 721
P P + G APP T P+ S G + PL + L S+ G
Sbjct: 78 GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA-EETVARG 136
Query: 722 ESSAAPSQPITAVKDMPVRSGGLLPDP-PRSSYLESPRGPRFDGPRRFEDLGSR--CEGP 778
+++ AP + + SG P P + G PR R EGP
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 779 RPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSL-SPRQSGPQW 837
R + P P P+ G G + R PAS+ + +T L SP +SGP
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAG-----GGLQR-PASRSLSSSATPLSSPARSGPSA 250
Query: 838 KGPKPAFGQQHQQQPK 853
+G A Q +PK
Sbjct: 251 RGTPRAPAHPSQPKPK 266
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/150 (26%), Positives = 49/150 (32%), Gaps = 21/150 (14%)
Query: 1500 SSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPP----- 1554
S+ P PP P P PP P + P P+ P PPP
Sbjct: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360
Query: 1555 --LP----PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVL 1608
LP PP P P S + + + L + F + AP
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAV------HLLQAPFSPPPSPPVQAPFS 414
Query: 1609 PP--PPVHSSIPPPGPVP--MGMPPMSKPP 1634
PP PPV S PP P + PP+ PP
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPP 444
Score = 42.7 bits (99), Expect = 0.004
Identities = 33/136 (24%), Positives = 47/136 (34%), Gaps = 25/136 (18%)
Query: 1501 SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP--PP 1558
+ P P G PP PP P+ P SS T P P P PP L P
Sbjct: 258 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317
Query: 1559 PPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIP 1618
PP P + + ++ + +PS P+ P ++ P
Sbjct: 318 PPATPPSQATTSLG-------------------SPTLQATHSFLPSPPLSP----LATPP 354
Query: 1619 PPGPVPMGMPPMSKPP 1634
P P + +PP+ PP
Sbjct: 355 PQAPPALALPPLQAPP 370
Score = 41.6 bits (96), Expect = 0.008
Identities = 50/200 (25%), Positives = 65/200 (32%), Gaps = 43/200 (21%)
Query: 1474 QKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPA 1533
Q + P PP + +++ P PPP + PP + KPP P APPA
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-APPLQLAKPP-----PQAPPA 483
Query: 1534 RSSVPVTRPPVPIPPPP-----------PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGL 1582
++ P+ P P P P PL PPP P +A
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL----------- 532
Query: 1583 WDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIP------PPGPVPMGMPPMSKPPPV 1636
Q S S T P P P P S P PGP P PP P
Sbjct: 533 ------QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP---PPSRSPSST 583
Query: 1637 QQTVDYGHGRDISTNKVEQI 1656
D +T+ E++
Sbjct: 584 LSGPDLAGHSSSATSTPEEL 603
Score = 41.2 bits (95), Expect = 0.011
Identities = 70/304 (23%), Positives = 110/304 (36%), Gaps = 38/304 (12%)
Query: 101 QPPPPPMPPPPGPALSYQ---KQQQYKHQMLHHQRDGPPG-LVPMELESPPESPPV---- 152
+PP P PPPP + + + L + G G +P ES P + P
Sbjct: 28 RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP---ESAPRAGPTRTSR 84
Query: 153 PP----GSYMPPSQSYMPPPQPPPSYYPPTSSQ-PYLPPAQPSPSQSPPSQSYLAPTPSY 207
PP G PP+++ P P P T+ P ++ ++ P
Sbjct: 85 PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 144
Query: 208 SSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLES 267
S+ S+ ++ S PS + +R S+ L P PSA P T ++ + S
Sbjct: 145 SALSAGARRDTSGPTPGTPS--PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202
Query: 268 GAKNKSTEQQQAA---PEPDPSTMTPQEQQQYWYRQHLLSLQQ-----RTKVHLPGHKKG 319
+++ +TE AA P P + L S + R P H
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262
Query: 320 P----VVAKDTPE--PVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPP-----PLPPEE 368
P + A P+ P +++ PA + SP + P PP+ PP P PP
Sbjct: 263 PKPKGLQALRPPQVTPPRKD-AAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321
Query: 369 PQSE 372
P S+
Sbjct: 322 PPSQ 325
Score = 37.7 bits (86), Expect = 0.12
Identities = 41/174 (23%), Positives = 55/174 (31%), Gaps = 32/174 (18%)
Query: 1490 PPQESRLQNTSSRPGMYP-------PPGSYRPPPPMGKP----PGSIVRPSAPPARSSVP 1538
PP ++ +S PG P P PPP P P V PS P + +
Sbjct: 487 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546
Query: 1539 VTRPPVP---------------IPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
RPP P P PPPPP P + P + +
Sbjct: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606
Query: 1584 DTNDEQGLNSEFKSETAAIPSAPVL----PPPPVHSSIPPPGPVPMGMPPMSKP 1633
D+ E G + + P P PP+ P P+P PP + P
Sbjct: 607 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP--WPPATGP 658
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 104 bits (260), Expect = 8e-22
Identities = 102/392 (26%), Positives = 135/392 (34%), Gaps = 98/392 (25%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSF--------REQHLAQL----- 61
PPPP PPPPP P P P S S A ++ F+ + QH L
Sbjct: 629 PPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPT 688
Query: 62 QQLQQMHQKQMQCVLQPHH-LPPPPLPPPPVMPGGGYGDWQPPP-----PPMPPPPGPAL 115
+ Q + Q ++ P+ +PPPP PPPP PG +P P P PP P
Sbjct: 689 PPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLK 748
Query: 116 SYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPP----------SQSYM 165
+Q Q + PP P+ PP++PP P + P +Q+
Sbjct: 749 IHQVQ-----HITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803
Query: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYL 225
P P PP PP QP P + P SPP+ P P+ L QS+
Sbjct: 804 PTPTPP---VPPAKKQPAFPASYIPP--SPPTPPVPVPPPT-----------LPKQQSFC 847
Query: 226 PSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDP 285
SP P K PPP PP ++ +PL +P P
Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPP----AMESQPL----------------KPVP 887
Query: 286 STMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPES 345
+ + PQ P K P+ + VP+ P
Sbjct: 888 ANVAPQ---------------------------SPPAVKAKPKWQPSSIPVPSPDFPPPP 920
Query: 346 PSSEEPPLPPPNEEVPPPLPPEEPQSEDPEED 377
P S PPP VP P PP P + P D
Sbjct: 921 PESSLVFPPPPPSPVPAP-PPPPPPTASPTPD 951
Score = 101 bits (252), Expect = 7e-21
Identities = 106/362 (29%), Positives = 141/362 (38%), Gaps = 42/362 (11%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75
PP PPPPP+ P P T PA P+S+ ++ A + + Q
Sbjct: 760 PPTPPPPPPIPAPLPPQAPPKPLVTIPA-PTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA 818
Query: 76 LQPHHLPP----PPLP-PPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHH 130
++PP PP+P PPP +P + PPP P P P++ Q Q+
Sbjct: 819 FPASYIPPSPPTPPVPVPPPTLPK--QQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPP 876
Query: 131 QRDGPPGLVPMELESPPESPP-VPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQP 189
+ P L P+ P+SPP V PS +P P PP PP S PP P
Sbjct: 877 AMESQP-LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPP---PPPESSLVFPPPPP 932
Query: 190 S--PSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAP 247
S P+ PP +PTP S S S S P +P R S S S P
Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP--PPTPQRNSSIKSSSGAEHP 990
Query: 248 PPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQ 307
P + + P ESG+ +K T AAP P P +
Sbjct: 991 EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAP-PKPGKL------------------N 1031
Query: 308 RTKVHLPG-HKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPP 366
+ V+LPG ++G V AK PV + + P PS + P PPP E+ PLPP
Sbjct: 1032 LSGVNLPGVLQQGCVSAK---APVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL--PLPP 1086
Query: 367 EE 368
E
Sbjct: 1087 IE 1088
Score = 93.6 bits (231), Expect = 2e-18
Identities = 113/451 (25%), Positives = 162/451 (35%), Gaps = 68/451 (15%)
Query: 508 NQYMGNMSMPP-PFVPYSQMPPPLPTMPPP-VLPPSLPPPVMPPALPATVPPPGMPPPVM 565
+Q+ G + PP P V SQ P +PP V+PP PPP PP P + P P
Sbjct: 677 SQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPP--PPPTPGSAMAQLKPAPCA 734
Query: 566 PPSLPTSVPPPGMP----PSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPL 621
P S PPP + ++ PP PPP + + PP P P ++ AP +
Sbjct: 735 PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTV 794
Query: 622 PPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAP 681
P+ + PP PP P P A+ +PP+ + VP P LP SF + P
Sbjct: 795 APVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP----PPTLPKQQSFCAKP 850
Query: 682 PTTYHPPLQSAGPSEQVNSK-----APLSKSALPYSSFSSDQGLGESSAAPSQPITAVKD 736
P + P+ S +Q+ S+ P + + P ++ A ++P
Sbjct: 851 PPSPLSPVPSV--VKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSS 908
Query: 737 MPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPR 796
+PV S P PP SS + P P S P P P PD +
Sbjct: 909 IPVPSPDFPPPPPESSLVFPPPPP------------SPVPAPPPPPPPTASPTPD--KSG 954
Query: 797 YEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQA 856
G T S G P TP + S + S G +H + +
Sbjct: 955 SPGKKTSKTSSPGGKKPPP-------TPQRNSSIKSSS----------GAEHPEPKRPSV 997
Query: 857 EPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQE-------- 908
+ L P A++ S ++ AA K K S NL Q+
Sbjct: 998 DSLVSKFTPPAESGSPSKETLPPP------AAPPKPGKLNLSGVNLPGVLQQGCVSAKAP 1051
Query: 909 ----PPKSEVSEGPVEPSNWDQNVQSMETQI 935
K V E P PS+ D ET++
Sbjct: 1052 VLSGRGKDSVVEFPSPPSDSDFPPPPPETEL 1082
Score = 73.9 bits (180), Expect = 2e-12
Identities = 89/352 (25%), Positives = 127/352 (36%), Gaps = 67/352 (19%)
Query: 63 QLQQMHQKQMQCVLQPH-HLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGP-------- 113
QL++ + +M+ + +P+ L PP P P ++ PP PP PPPP P
Sbjct: 586 QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP 645
Query: 114 ---------------ALSYQKQQQYKHQMLHHQRDG----PPGLVPMELESPPESPPVPP 154
A + K Q G PP M+ +S VPP
Sbjct: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705
Query: 155 GSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSS 214
+PP PPP PPP+ P S+ L PA +PS + AP P
Sbjct: 706 NGVVPPP----PPPPPPPT---PGSAMAQLKPAPCAPS----LPQFSAPPPPLK------ 748
Query: 215 QSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKST 274
H ++ +Q +P P + AP PP APP T+ P + K +
Sbjct: 749 ----IHQVQHI--TQVAPPTPP---PPPPIPAPLPPQAPPKPLVTI---PAPTSTKTVAP 796
Query: 275 EQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPG---HKKGPVVAKDTPEPVK 331
QAAP + P ++Q + ++ V +P K+ AK P P+
Sbjct: 797 VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLS 856
Query: 332 EEVTVPATSQVPESPSSEEPPLPPPNEEVPP--PLPPEEPQSEDPEEDARLK 381
P S V + S PP PP E P P+P P A+ K
Sbjct: 857 -----PVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPK 903
Score = 70.1 bits (170), Expect = 2e-11
Identities = 58/203 (28%), Positives = 78/203 (38%), Gaps = 28/203 (13%)
Query: 1457 LKAAQELKMLREQKEQLQKMKDFG-SEPQMADHLPPQE--SRLQNTSSRPGMYPPPGSYR 1513
+K+ + E + D G S+ Q A H+ Q S + + + + G S
Sbjct: 534 IKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKA 593
Query: 1514 PPPPMGKPPGSIVRPSAPPARSSVPVTR----PPVPIPPPPPPPPLPPPPPVIKPQTSAV 1569
M +P S+V P +P + P T PP+P PPPPPPPP PPPPP P S
Sbjct: 594 RMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQS 653
Query: 1570 EQERWDEDSFYGLWDT-----NDEQGLNSEFKSETAAI------------PSAPVLPPPP 1612
+ + T N Q + FK T + P V+PPPP
Sbjct: 654 APSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP 713
Query: 1613 VHSSIPPPGPVPMGMPPMSKPPP 1635
PPP P P KP P
Sbjct: 714 P----PPPPPTPGSAMAQLKPAP 732
Score = 70.1 bits (170), Expect = 2e-11
Identities = 58/192 (30%), Positives = 77/192 (40%), Gaps = 40/192 (20%)
Query: 1508 PPGSYRPPPPMGKPPG---SIVRPSAPPARSSVPVTRPPVPIPPP-----------PPPP 1553
PP P PP K P S + PS P PPVP+PPP PPP
Sbjct: 803 PPTPTPPVPPAKKQPAFPASYIPPSPPT---------PPVPVPPPTLPKQQSFCAKPPPS 853
Query: 1554 PLPPPPPVIK---------PQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPS 1604
PL P P V+K P A+E + + +++ + +PS
Sbjct: 854 PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS 913
Query: 1605 APVLPPPPVHSSI--PPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERI 1662
P PPPP SS+ PPP P P+ PP PP T D T+K P G+
Sbjct: 914 -PDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSS-PGGK-- 969
Query: 1663 TLRPDPLPERST 1674
+P P P+R++
Sbjct: 970 --KPPPTPQRNS 979
Score = 57.8 bits (138), Expect = 1e-07
Identities = 60/198 (30%), Positives = 79/198 (39%), Gaps = 45/198 (22%)
Query: 1473 LQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMG----KPPGSIVRP 1528
L K + F ++P + L P S ++ +S+ +PPP + PP M KP + V P
Sbjct: 840 LPKQQSFCAKPPPSP-LSPVPSVVKQIASQ---FPPPPT---PPAMESQPLKPVPANVAP 892
Query: 1529 SAPPA--------RSSVPVTRPPVPIPPP------PPPPPL------PPPPPVIK--PQT 1566
+PPA SS+PV P P PPP PPPPP PPPPP P
Sbjct: 893 QSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDK 952
Query: 1567 SAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLP---------PPPVHSSI 1617
S ++ + S G NS KS + A P P PP S
Sbjct: 953 SGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGS 1012
Query: 1618 PPPGPVPMGMPPMSKPPP 1635
P +P PP + P P
Sbjct: 1013 PSKETLP---PPAAPPKP 1027
Score = 53.9 bits (128), Expect = 2e-06
Identities = 63/273 (23%), Positives = 89/273 (32%), Gaps = 97/273 (35%)
Query: 1423 SHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSE 1482
S+HS++ SD+ + Q G V R I+ E Q E+ K +
Sbjct: 548 SNHSNQ---SDSGVSDTQPAGHV-----RSQSIVSSVFSEAWKRGTQLEESSKARMESMN 599
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPP-------------------- 1522
+PP + + + P P PPPP PP
Sbjct: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGS 659
Query: 1523 ---------------------GSIVRPSAPPARSSVPVTRPPVPIPP----PPPPPPLPP 1557
G++ +P PP S V +P + +PP PPPPPP PP
Sbjct: 660 AAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV-KPQILVPPNGVVPPPPPPPPP 718
Query: 1558 PPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVL--PPPP--V 1613
P P SA+ Q + PS P PPPP +
Sbjct: 719 PTP-----GSAMAQLK------------------------PAPCAPSLPQFSAPPPPLKI 749
Query: 1614 HS----------SIPPPGPVPMGMPPMSKPPPV 1636
H + PPP P+P +PP + P P+
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPL 782
Score = 52.0 bits (123), Expect = 6e-06
Identities = 47/173 (27%), Positives = 62/173 (35%), Gaps = 33/173 (19%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPG----------------SIVRPSAPPA 1533
PP +Q+ S +P + PP PPPP PP S+ + SAPP
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP 745
Query: 1534 RSSV-----------PVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGL 1582
+ P PP PIP P PP PP P V P ++ +
Sbjct: 746 PLKIHQVQHITQVAPPTPPPPPPIP-APLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP 804
Query: 1583 WDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
T + + IP +P PP PV PP +P +KPPP
Sbjct: 805 TPTPPVPPAKKQPAFPASYIPPSPPTPPVPV-----PPPTLPKQQSFCAKPPP 852
Score = 51.6 bits (122), Expect = 8e-06
Identities = 72/318 (22%), Positives = 103/318 (32%), Gaps = 44/318 (13%)
Query: 11 SSHYPPPP------VPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQL 64
S +PPPP PPPPP +P P P ++S TP S G + + +
Sbjct: 913 SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP 972
Query: 65 QQMHQKQMQCVLQPHHLPPPPLPP---------PPVMPGGGYGDWQPPPPPMPPPPGPAL 115
+ P P P PP G + PPP P P L
Sbjct: 973 PTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNL 1032
Query: 116 SYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQP----- 170
S Q + P L +S E P PPS S PPP P
Sbjct: 1033 SGVNLPGVLQQGCVSAK--APVLSGRGKDSVVEFPS-------PPSDSDFPPPPPETELP 1083
Query: 171 -PPSYYPPT---SSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLP 226
PP P ++ P + P P Q AP P+ + S++ +
Sbjct: 1084 LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPT 1143
Query: 227 SSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESG--------AKNKSTEQQQ 278
+ P P+ S L+ P N+T ++ G A+ +T
Sbjct: 1144 MATVVPQVPT---SPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDM 1200
Query: 279 AAPEPDPSTMTPQEQQQY 296
A P P P ++ Q++ Y
Sbjct: 1201 ALPPPPPELLSDQQKAGY 1218
Score = 45.1 bits (105), Expect = 8e-04
Identities = 33/136 (24%), Positives = 48/136 (35%), Gaps = 8/136 (5%)
Query: 297 WYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPP 356
W R L + ++ +V +P+P ++ P T+ P P PP PPP
Sbjct: 581 WKRGTQLEESSKARMESMNRPYTSLVPPLSPQP---KIVTPYTASQPSPPLPPPPPPPPP 637
Query: 357 NEEVPPPLPPEEPQSEDPEEDARLKQL--QAAAAHWQQHQQHRVGF---QYQGIMQKHTQ 411
PPP PP P P + + Q QH +MQ +
Sbjct: 638 PPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV 697
Query: 412 LQQILQQYQQIIQPPP 427
QIL ++ PPP
Sbjct: 698 KPQILVPPNGVVPPPP 713
Score = 42.0 bits (97), Expect = 0.006
Identities = 69/296 (23%), Positives = 97/296 (32%), Gaps = 47/296 (15%)
Query: 522 PYSQMPPPLPTM------------PPPVLPP--SLPPPVMPPALPATVPPPGMPPPVMPP 567
P + PPP P P P P SL PPA + +PPP PP
Sbjct: 966 PGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025
Query: 568 SLP----TSVPPPGM---------PPSLSSAGPPPVL--PPPSLSSAGPPPVLPPPSLSS 612
+ V PG+ P LS G V+ P P S PPP PP
Sbjct: 1026 KPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPP---PPETEL 1082
Query: 613 TAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLP 672
PP +P + +P + P Q + AP P S + + P
Sbjct: 1083 PLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQP 1142
Query: 673 TPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPIT 732
T + PT+ L S P + L + ++ + G S + ++P
Sbjct: 1143 TMATVVPQVPTSPKSSL-SVQPGFLADLNRTLQRKSI------TRHGSLSSRMSRAEPTA 1195
Query: 733 AVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGN 788
+ DM L P PP L S + G + GP P P+ + N
Sbjct: 1196 TMDDM-----ALPPPPPE---LLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQN 1243
Score = 35.0 bits (79), Expect = 0.79
Identities = 21/45 (46%), Positives = 22/45 (48%), Gaps = 6/45 (13%)
Query: 1599 TAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYG 1643
TA+ PS P LPPPP PPP P P PP P P Q G
Sbjct: 620 TASQPSPP-LPPPP-----PPPPPPPPPPPPPPPPLPSQSAPSAG 658
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 104 bits (260), Expect = 8e-22
Identities = 83/231 (35%), Positives = 95/231 (41%), Gaps = 46/231 (19%)
Query: 493 QSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALP 552
QS Q K S + + PP VP SQ+ P PPP+ PP PP + PP P
Sbjct: 369 QSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPP-LRPPGPP 427
Query: 553 ATVPP---PGMPPPVMPPSLP----------TSVPPPGMPPSLSSAGPPPVLPPPSLSSA 599
+PP PG PP + PP +P PPPG PP GPPP LPP
Sbjct: 428 TGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPG-PPPGPPPGLPP------ 480
Query: 600 GPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQS 659
GPPP PPP L PPP PPGIPPP PP VPP +
Sbjct: 481 GPPPRGPPPRL----PPPA-----------PPGIPPPRPGMMRPPL-----VPPLGPAPP 520
Query: 660 SQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALP 710
P PA LP P SAPP P + + KA + SA P
Sbjct: 521 GLFP----PAPLPNP-GVLSAPPNLIQRPKADDTSAATIEKKATATISAKP 566
Score = 72.8 bits (177), Expect = 3e-12
Identities = 64/181 (35%), Positives = 78/181 (43%), Gaps = 24/181 (13%)
Query: 518 PPFVPYSQMPPP--LPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPP 575
PP +P + P P LP PPP PP PPP PP LP PP G PPP +PP P +PP
Sbjct: 444 PPGMPGLRGPLPRLLPPGPPPGRPPG-PPPGPPPGLPPGPPPRG-PPPRLPPPAPPGIPP 501
Query: 576 P--GM--PPSLSSAGPPPV-------LPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPL 624
P GM PP + GP P LP P + SA P + P + ++A
Sbjct: 502 PRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATAT 561
Query: 625 SSATPPPGIPPPGVPQGIPPQLT-------AAPVPPASSSQSSQVP-EKPRPALLPT-PV 675
SA P P + + +P L A P S S VP K P P+ PV
Sbjct: 562 ISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAVPLAKAAPKSGPSVPV 621
Query: 676 S 676
S
Sbjct: 622 S 622
Score = 62.4 bits (150), Expect = 5e-09
Identities = 69/264 (26%), Positives = 100/264 (37%), Gaps = 68/264 (25%)
Query: 12 SHYPPPPVPPPPPVALPEASP--GPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69
S PP+P PPP+ P A P PG + P P +
Sbjct: 400 SQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGA--------------------- 438
Query: 70 KQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPP---PPGPALSYQKQQQYKHQ 126
L+P +P P P ++P G P PPP PP PPGP
Sbjct: 439 ---PPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPP------------ 483
Query: 127 MLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQP-PPSYYPPTS-SQPYL 184
R PP L P +PP PP PG PP +PP P PP +PP P +
Sbjct: 484 ----PRGPPPRLPP---PAPPGIPPPRPGMMRPP---LVPPLGPAPPGLFPPAPLPNPGV 533
Query: 185 PPAQPSPSQSPPSQSYLAPT-PSYSSSSSSSQSYLSHSQS----YLPS----------SQ 229
A P+ Q P + A T ++++ S++ +++ ++ ++P+ +
Sbjct: 534 LSAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGAT 593
Query: 230 ASPSRPSQGHSKSQLLAPPPPSAP 253
A+P R S+ S L P S P
Sbjct: 594 AAPQRKSEDDSAVPLAKAAPKSGP 617
Score = 58.2 bits (139), Expect = 9e-08
Identities = 49/161 (30%), Positives = 59/161 (36%), Gaps = 45/161 (27%)
Query: 59 AQLQQLQQMHQKQMQCVLQPHHLPPPPLPPP----PVMPGGGYGDWQPPPPPMPPPPGPA 114
+Q Q ++ H PP +PP P MPG PPP+ PPP P
Sbjct: 370 SQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPG---------PPPLGPPPAPP 420
Query: 115 LSYQKQQQYKHQMLHHQRDGPP-GLVPMELESPPESPPV--PPG---------SYMPPSQ 162
L + GPP GL P PP +PP PPG +PP
Sbjct: 421 L---------------RPPGPPTGLPP---GPPPGAPPFLRPPGMPGLRGPLPRLLPPGP 462
Query: 163 SYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAP 203
PP PPP PP P PP P P PP+ + P
Sbjct: 463 PPGRPPGPPPG--PPPGLPPGPPPRGPPPRLPPPAPPGIPP 501
Score = 54.3 bits (129), Expect = 1e-06
Identities = 85/352 (24%), Positives = 120/352 (34%), Gaps = 97/352 (27%)
Query: 1326 RDIPSLPPLPPLPP--------------LPPLDRYRDDRWREERNREHGYDRDFRDRGEL 1371
R P PP PP P LPP R D + E + G+D D E
Sbjct: 197 RKPPGPPPGPPPPQVVQMYGRKVGFALDLPPRRRDEDMLYSPEL-AQRGHDDDVSSTSE- 254
Query: 1372 RIREYPERGDTWREKRDYVPDRMDWERERLSDRWYPSDVDRHSPMAEHMPSSHHSSEMMG 1431
YPE D ++K D D D ++ SD D H E + S +
Sbjct: 255 -DDGYPEDMD--QDKHDDSTDDSDTDK---SDGESDGDEFVHRDNGERDNNEEKKSGLSV 308
Query: 1432 SDASLD--SDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHL 1489
A + S + + L+ Q ++ A QE+ E+ ++++ + E D
Sbjct: 309 RFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIP---EEGREVEEFSEDDDEDDSDDSE 365
Query: 1490 PPQESRLQN---------TSSRPGMYPPPGSYRP----------PPPMGKPPGSIVRPSA 1530
++S+ Q+ +++ PP S P PPP+G PP +RP
Sbjct: 366 AEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPG 425
Query: 1531 PPAR-------SSVPVTRPP-VPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGL 1582
PP + P RPP +P P P LPP PP +P
Sbjct: 426 PPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRP------------------ 467
Query: 1583 WDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634
P P PPP + PPGP P G PP PP
Sbjct: 468 --------------------PGPPPGPPPGL-----PPGPPPRGPPPRLPPP 494
Score = 53.1 bits (126), Expect = 3e-06
Identities = 31/82 (37%), Positives = 36/82 (43%), Gaps = 9/82 (10%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPP-PPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548
PP PG+ P PP PP G+PPG P PP P R P P P
Sbjct: 435 PPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGP--PPGPPPGLPPGPPPRGPPPRLP 492
Query: 1549 PPPPPPLPPP------PPVIKP 1564
PP PP +PPP PP++ P
Sbjct: 493 PPAPPGIPPPRPGMMRPPLVPP 514
Score = 52.8 bits (125), Expect = 4e-06
Identities = 48/176 (27%), Positives = 59/176 (33%), Gaps = 70/176 (39%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGS-YRPP-PPMGKPPGS---------------------- 1524
+PP + + P + PPP RPP PP G PPG
Sbjct: 397 VPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPR 456
Query: 1525 IVRPSAPPARSSVPVTRPPVPIPPPP----PPPPLPPPPPVIKPQTSAVEQERWDEDSFY 1580
++ P PP R P PP +PP P PPP LPPP P P
Sbjct: 457 LLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIP---------------- 500
Query: 1581 GLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGM-PPMSKPPP 1635
P P + PP+ +PP GP P G+ PP P P
Sbjct: 501 ----------------------PPRPGMMRPPL---VPPLGPAPPGLFPPAPLPNP 531
Score = 42.7 bits (99), Expect = 0.004
Identities = 47/185 (25%), Positives = 66/185 (35%), Gaps = 29/185 (15%)
Query: 118 QKQQQYKHQMLHH---------QRDGPPGLVP-MELESPPESPPVPPGSYMPPSQSYMPP 167
+KQ Q +H+ H Q+ PP VP ++++PP P P G PP + P
Sbjct: 367 EKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLG---PPPAPPLRP 423
Query: 168 PQPPPSY--YPPTSSQPYL-PPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSY 224
P PP PP + P+L PP P P P P
Sbjct: 424 PGPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPG---------- 473
Query: 225 LPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD 284
P P P +G +L P PP PP + + + PL AP P+
Sbjct: 474 -PPPGLPPGPPPRG-PPPRLPPPAPPGIPP-PRPGMMRPPLVPPLGPAPPGLFPPAPLPN 530
Query: 285 PSTMT 289
P ++
Sbjct: 531 PGVLS 535
Score = 39.3 bits (90), Expect = 0.042
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 18/74 (24%)
Query: 541 SLPPPVMPPA----LPATVPPPGMPPPVM--------PPSLPTSVPP------PGMPPSL 582
S+P P MP A L +P PG PP + PP+ S+ P P +PP
Sbjct: 138 SIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGR 197
Query: 583 SSAGPPPVLPPPSL 596
GPPP PPP +
Sbjct: 198 KPPGPPPGPPPPQV 211
Score = 39.3 bits (90), Expect = 0.042
Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 6/75 (8%)
Query: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATP-- 629
S+P P MP + S+ ++ L A PP +L S V LP L P
Sbjct: 138 SIPLPDMPHAPSNI----LIQDIPLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRL 193
Query: 630 PPGIPPPGVPQGIPP 644
PPG PPG P G PP
Sbjct: 194 PPGRKPPGPPPGPPP 208
Score = 37.7 bits (86), Expect = 0.12
Identities = 34/125 (27%), Positives = 57/125 (45%), Gaps = 12/125 (9%)
Query: 1445 VMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPG 1504
++ L ++++ I K ++L++ EQK ++ + + A H+ + L + P
Sbjct: 92 ILRLYEKENPDIYKELRKLEVEYEQKRA--QLSQYFDAVKNAQHVEVESIPLPDMPHAPS 149
Query: 1505 MYPPPGSYRPPPPMGKPPGSIVRPSA--PPAR--SSVPVTRPPVPIPPP---PPPPPLPP 1557
P P +PP + + SA PP R S +P+ VP PP PP PP P
Sbjct: 150 NILIQDI---PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGP 206
Query: 1558 PPPVI 1562
PPP +
Sbjct: 207 PPPQV 211
Score = 33.9 bits (76), Expect = 1.8
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 12/87 (13%)
Query: 503 FQNMKN-QYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVM-------PPALPAT 554
F +KN Q++ S+P P +P++ + +P LP + PP ++ PP +
Sbjct: 125 FDAVKNAQHVEVESIPLPDMPHAPSNILIQDIP---LPGAQPPSILKKTSAYGPPTRAVS 181
Query: 555 VPPP-GMPPPVMPPSLPTSVPPPGMPP 580
+ P G P +PP PPPG PP
Sbjct: 182 ILPLLGHGVPRLPPGRKPPGPPPGPPP 208
Score = 33.5 bits (75), Expect = 2.3
Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 7/73 (9%)
Query: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP---PPPPPLPPPP 1559
P + PP PPP PG + P PP + P PP P+P P PP L P
Sbjct: 489 PRLPPPAPPGIPPP----RPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRP 544
Query: 1560 PVIKPQTSAVEQE 1572
+ +E++
Sbjct: 545 KADDTSAATIEKK 557
Score = 31.6 bits (70), Expect = 8.8
Identities = 32/134 (23%), Positives = 51/134 (38%), Gaps = 12/134 (8%)
Query: 1596 KSETAAIPSAPVLPPPPVHSSIP--PPGPVPMGMPPMSKPPPVQQTV--DYGHGRDISTN 1651
K+ P+ V P + +P PPG P G PP PP V Q G D+
Sbjct: 169 KTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVVQMYGRKVGFALDLPPR 228
Query: 1652 KVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKR 1711
+ + E + P+ + + D Y + D++ + D + D D +
Sbjct: 229 RRD-----EDMLYSPELAQRGHDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGES 283
Query: 1712 DRE--THRDR-DRD 1722
D + HRD +RD
Sbjct: 284 DGDEFVHRDNGERD 297
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 103 bits (257), Expect = 2e-21
Identities = 110/432 (25%), Positives = 157/432 (36%), Gaps = 111/432 (25%)
Query: 13 HYPPPP---VPP---------PPPV--ALPEASPGPGYSSSTTPAAPSSSGFMSFREQHL 58
H P PP PP PP + ALP+ P ++ P P+ +S L
Sbjct: 838 HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVS---PAL 894
Query: 59 AQLQQLQQMHQKQ-MQCVLQPHHLPPPPL----------------PPPPVMPGGGYGDWQ 101
Q L Q Q Q +L+ P PPL PP P++P
Sbjct: 895 TQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLP--SVKVQS 952
Query: 102 PPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPS 161
PPPP+PPPP P++ Q QQQ PP PP PP PP
Sbjct: 953 QPPPPLPPPPHPSVQQQLQQQ------------PP-------------PPPPPQPQPPPQ 987
Query: 162 QSYMPPPQP---PPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYL 218
Q + PPP+P P + QP PP P PP Q P P + Q +
Sbjct: 988 QQHQPPPRPVHLQPMQFSTHIQQP-PPPQGQQPPHPPPGQQPPPPQP------AKPQQVI 1040
Query: 219 SHSQSYLPSSQASPSRPSQGHSKSQLLAPPP-----PSAPPGNKTTVQQEPLESGAKNKS 273
H S P S S GH + AP P P T Q P ++ K
Sbjct: 1041 QHHHS--PRHHKSDPY-STGHLRE---APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQ 1094
Query: 274 TEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEE 333
+ + +P P + +E K+H P + P PEP K
Sbjct: 1095 ELRAASVVQPQPLVVVKEE-----------------KIHSPIIRSEPFSPSLRPEPPKHP 1137
Query: 334 VTVPATSQVPESPSSE-----EPPLPPPNEEVPPPLPPEEPQSED-------PEEDARLK 381
++ A +P+ P + P + PP + PPP P++ + + P++D ++K
Sbjct: 1138 ESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIK 1197
Query: 382 QLQAAAAHWQQH 393
+ + A+ Q+H
Sbjct: 1198 NMGSWASLVQKH 1209
Score = 101 bits (252), Expect = 7e-21
Identities = 131/526 (24%), Positives = 177/526 (33%), Gaps = 93/526 (17%)
Query: 110 PPGPALSYQKQQQYKHQMLHHQR-DGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPP 168
P + ++Q KH HHQ+ P VP + PP+ PP PP PP Q PPP
Sbjct: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPP----PPQQQQQPPP 778
Query: 169 QPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT--PSYSSSSSSSQSYLSHSQSYLP 226
PP PP+ Q P + SP PP + P P S + + +LP
Sbjct: 779 PPP----PPSMPQQAAPAMKSSP---PPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLP 831
Query: 227 SSQASPSRP------SQGHSKSQLLAPPP---------PSAPPGNKTTVQQEPLESGAKN 271
+ P P + H + PP PS P + +P A +
Sbjct: 832 QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVS 891
Query: 272 KSTEQQQAAPEPDPSTMTPQ---EQQQ-----YWYRQHLLSLQQRTKVHLPGHKKGPVVA 323
+ Q P+P P PQ E ++ Q L LQQ KV P V
Sbjct: 892 PALTQTPLLPQP-PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKV 950
Query: 324 KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQL 383
+ P P P+ Q ++PP PPP P P PP + Q + P L+ +
Sbjct: 951 QSQPPPPLPPPPHPSVQQ----QLQQQPPPPPP----PQPQPPPQQQHQPPPRPVHLQPM 1002
Query: 384 QAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEM 443
Q + H QQ QG H Q QPPP Q ++H+
Sbjct: 1003 Q-FSTHIQQPPPP------QGQQPPHPPPGQ---------QPPPP-QPAKPQQVIQHHHS 1045
Query: 444 QQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSF 503
+ Y +HS P Q Q H Q +Q K
Sbjct: 1046 PRHHKSDPYSTGHLREAPSPLMIHS-PQMSQFQSLT--------HQSPPQQNVQPKKQEL 1096
Query: 504 QNMKNQYMGNMSMPPPFV---------PYSQMPPPLPTM--PPPVLPPSLPPPVMPPALP 552
+ ++ P P V P + P P++ PP P S+ PV P P
Sbjct: 1097 R------AASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRP 1150
Query: 553 ATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPP--PVLPPPSL 596
P P + PP + PPPG P P PV P L
Sbjct: 1151 EMKPVDVGRPVIRPPE--QNAPPPGAPDKDKQKQEPKTPVAPKKDL 1194
Score = 89.4 bits (220), Expect = 4e-17
Identities = 209/992 (21%), Positives = 327/992 (32%), Gaps = 194/992 (19%)
Query: 17 PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVL 76
P VPPP V P +S S S++ + S+ R Q LA+LQ+ + +Q+ +
Sbjct: 471 PAVPPPTKVVAPPSSSDSS-SDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALS 529
Query: 77 QPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPP 136
QP +P ++++++ + ++ PP
Sbjct: 530 QPQQN-------------------KPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPP 570
Query: 137 GLVPMELESPP---ESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQ 193
S + P P S PP+ + P Y P
Sbjct: 571 KKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKL 630
Query: 194 SPPSQSYLAPTPSYSSSSSSS---------QSYLSHSQSYLPSSQASPSRPSQGHSKSQL 244
+ PS +S+ S L + Y+ S +P K +
Sbjct: 631 GRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA--EKVDV 688
Query: 245 LAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLS 304
+A S G ++ + ES + + + + AP+ +EQ+++ + H
Sbjct: 689 IAGS--SKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQ-Q 745
Query: 305 LQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPL 364
+QQ P PV P PPP + PPP
Sbjct: 746 MQQ------------------APAPV--------------------PQQPPPPPQQPPPP 767
Query: 365 PPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQ 424
PP + Q + P Q AA +
Sbjct: 768 PPPQQQQQPPPPPPPPSMPQQAAPAMKS-------------------------------S 796
Query: 425 PPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKT 484
PPP I T + + ++ F + + L + +L PH Q E+
Sbjct: 797 PPPFIATQ---VPVLEPQLPGSVFDPIGHFTQPILHLPQPELP--PHLPQPPEH------ 845
Query: 485 WQGHMKATQSYL-QEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLP 543
+T +L Q V S + N S P S LP P P PP++
Sbjct: 846 ------STPPHLNQHAVVSPPALHNALPQQPSRP------SNRAAALP--PKPARPPAVS 891
Query: 544 PPV-MPPALPATVPPPGMPPPVM-----PPSLP-TSVPPPGMPPSLSSAGPP-PVLPPPS 595
P + P LP PP PP V+ PP+ P TS+ L PP P+LP
Sbjct: 892 PALTQTPLLPQ--PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVK 949
Query: 596 LSSAGPPPVLPPPSLS--------STAPPPVMPLPPLSSATPPPGIP--------PPGVP 639
+ S PPP+ PPP S PPP P PP PP P +
Sbjct: 950 VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQ 1009
Query: 640 QGIPPQLTAAPVPPASSSQSSQVPEKPRPALL--PTPVSFGSAPPTTYH-----PPLQSA 692
Q PPQ P PP P KP+ + +P S P +T H PL
Sbjct: 1010 QPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIH 1069
Query: 693 GPSEQVNSKAPLSKSALPYSSFS-SDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRS 751
P Q++ L+ + P + Q L +S QP+ VK+ + S + +P
Sbjct: 1070 SP--QMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP 1127
Query: 752 SYLESPRGPRFDGPRRFEDLGSRCEGP-RPKGPRFEGNRPDGPRPRYEGHPAEGT--KSK 808
S P P+ E + + P RP+ + RP RP + P G K K
Sbjct: 1128 SLRPEP-------PKHPESIKAPVHLPQRPEMKPVDVGRP-VIRPPEQNAPPPGAPDKDK 1179
Query: 809 WGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLAD 868
P+ P + P L + G W + Q+H P S A+ S + E
Sbjct: 1180 QKQEPKTP-----VAPKKDLKIKNMG-SW----ASLVQKHPTTPSSTAKSSSDSFEQFRR 1229
Query: 869 TSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNV 928
+ +++ K A A+ + + + + S+++ E + E + Q
Sbjct: 1230 AAREKEEREK----ALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQ 1285
Query: 929 QSMETQIDKAQAVTQPVPLANKPVP-AQSTFP 959
Q + Q + Q Q +A P AQS+ P
Sbjct: 1286 QQQQRQEQQQQQQQQAAAVAAAATPQAQSSQP 1317
Score = 87.4 bits (215), Expect = 1e-16
Identities = 164/775 (21%), Positives = 273/775 (35%), Gaps = 113/775 (14%)
Query: 232 PSRPSQGHSKSQLLAPPPPS---APPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTM 288
P P + A PPP+ APP + + +S + +E+++A +
Sbjct: 458 PDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERA------QRL 511
Query: 289 TPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSS 348
++Q + L +L Q + +K K KEEV S+ E P
Sbjct: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571
Query: 349 EEPPLPPPNEEV----PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGF-QYQ 403
+ N V P P+ + P + + EE+ + K + +++ +Q + +
Sbjct: 572 KTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMS-----YEEKRQLSLDINKLP 626
Query: 404 GIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWE 463
G +K ++ I+Q + ++ + + +D + ++ +++ ++ +
Sbjct: 627 G--EKLGRVVHIIQSREPSLK-NSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 683
Query: 464 EQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMG----------N 513
E++ +++ + ++ S E + ++ K + G +
Sbjct: 684 EKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHH 743
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPPSL----PPPVMPPALPATVPP--PGMPP----- 562
M P Q PPP P PPP PP PPP PP++P P PP
Sbjct: 744 QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIAT 803
Query: 563 --PVMPPSLPTSV--------------PPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLP 606
PV+ P LP SV P P +PP L PP PP L+ V+
Sbjct: 804 QVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQ--PPEHSTPPHLNQHA---VVS 858
Query: 607 PPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAP-VPPASSSQSSQV--- 662
PP+L + P P P + A P P P P + P LT P +P +Q QV
Sbjct: 859 PPALHNALPQ--QPSRPSNRAAALP--PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLE 914
Query: 663 -PEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLG 721
E P P L + PP PS +V S+ P P+ S Q L
Sbjct: 915 DEEPPAPPLTSMQMQLYLQQLQKVQPPTPLL-PSVKVQSQPPPPLPPPPHPSV--QQQLQ 971
Query: 722 ESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPK 781
+ P P P PP + P P P +F + + P P
Sbjct: 972 QQPPPPPPP--------------QPQPPPQQQHQPPPRPVHLQPMQF---STHIQQPPPP 1014
Query: 782 GPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPK 841
+G +P P P + P + K P+ + P +G + P
Sbjct: 1015 ----QGQQPPHPPPGQQPPPPQPAK------PQQVIQHHHSPRHHKSDPYSTGHLREAPS 1064
Query: 842 PAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNEN 901
P Q SQ + L+ P + Q K ++++A+ + VK + +
Sbjct: 1065 PLMIHSPQM---SQFQSLTHQSPPQQNV---QPKKQELRAASVVQPQPLVVVKEEKIHSP 1118
Query: 902 LSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPV---PLANKPVP 953
+ S+ P S E P P + V + K V +PV P N P P
Sbjct: 1119 IIRSEPFSP-SLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPP 1172
Score = 86.3 bits (212), Expect = 3e-16
Identities = 198/894 (22%), Positives = 300/894 (33%), Gaps = 183/894 (20%)
Query: 187 AQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQ---GHSKSQ 243
A SP+ PP++ P+ S SSS SSS S S S +Q Q H +
Sbjct: 467 AVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLA 526
Query: 244 LLAPPPPSAPP----------------------GNKTTVQQEPLESGAKNKSTEQQQAAP 281
L+ P + P K+ ++ P + KN S+ +
Sbjct: 527 ALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKK 586
Query: 282 EPDP--STMTPQEQQQYWYRQHLLSLQQRTKVHL-----PGHKKG----------PVVAK 324
EP P S P + + + +S +++ ++ L PG K G P +
Sbjct: 587 EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKN 646
Query: 325 DTPEPVKE--EVTVPATSQVPE-----------SPSSEEPPLPPPNEEVPPPLPPE-EPQ 370
P+ ++ E P+T + E P +E+ + + ++ E E
Sbjct: 647 SNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS 706
Query: 371 SEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQ 430
SE D+ + + A + + H Q + H Q+QQ Q PPP
Sbjct: 707 SESSSSDSEDSETEMAPK--SKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQP 764
Query: 431 TMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMK 490
Q QQQQ P Q+ K+
Sbjct: 765 PPPPPPQ------QQQQ-----------------PPPPPPPPSMPQQAAPAMKSSPPPFI 801
Query: 491 ATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSL------PP 544
ATQ + E +G+ + P +P ++PP LP P PP L P
Sbjct: 802 ATQVPVLEP--QLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSP 859
Query: 545 PVMPPALP----------ATVPP-PGMPPPVMP--------PSLPTSVPP--------PG 577
P + ALP A +PP P PP V P P P + PP P
Sbjct: 860 PALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPP 919
Query: 578 MPP-----------SLSSAGPP-PVLPPPSLSSAGPPPVLPPPSLS--------STAPPP 617
PP L PP P+LP + S PPP+ PPP S PPP
Sbjct: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPP 979
Query: 618 VMPLPPLSSATPPPGIP--------PPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPA 669
P PP PP P + Q PPQ P PP P KP+
Sbjct: 980 PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQV 1039
Query: 670 LLP--TPVSFGSAPPTTYH-----PPLQSAGPSEQVNSKAPLSKSALPYSSFS-SDQGLG 721
+ +P S P +T H PL P Q++ L+ + P + Q L
Sbjct: 1040 IQHHHSPRHHKSDPYSTGHLREAPSPLMIHSP--QMSQFQSLTHQSPPQQNVQPKKQELR 1097
Query: 722 ESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGP-RP 780
+S QP+ VK+ + S + +P S P P+ E + + P RP
Sbjct: 1098 AASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEP-------PKHPESIKAPVHLPQRP 1150
Query: 781 KGPRFEGNRPDGPRPRYEGHPAEGT--KSKWGMIPRGP---------------ASQFYIT 823
+ + RP RP + P G K K P+ P AS
Sbjct: 1151 EMKPVDVGRPV-IRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKH 1209
Query: 824 PST-SLSPRQSGPQWKGPKPAFGQQHQQQP--KSQAEPLSGNKEPLADTSSNQQKNFKMQ 880
P+T S + + S ++ + A ++ +++ K+QAE KE L +++
Sbjct: 1210 PTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDAL 1269
Query: 881 SAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQ 934
A + + + Q + QQ+ ++ P QSM Q
Sbjct: 1270 EQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
Score = 57.4 bits (137), Expect = 1e-07
Identities = 91/374 (24%), Positives = 135/374 (36%), Gaps = 56/374 (14%)
Query: 339 TSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRV 398
TSQ+ + + +P P N P PPE P+ Q + +H+
Sbjct: 23 TSQMSTTQAQAQPQ--PANAASTNPPPPETSNPNKPKRQTNQLQYLLRVV-LKTLWKHQF 79
Query: 399 GFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWERE 458
+ +Q Q ++ L Y +II+ P + T+ ++ +Y Q+ Q +
Sbjct: 80 AWPFQ---QPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNC 136
Query: 459 FQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPP 518
+ +++ P D + E K + K + +E K + G
Sbjct: 137 Y------IYNKPGDDIVLMAEALEKLFL--QKINELPTEETEIMIVQAKGRGRGRKETGT 188
Query: 519 PFVPYSQMPPPLPTMPPPVL--PPSLPPPVM--PPALPATVPPPGMPPPVMPPSLPTSVP 574
S +P PP P PPPV P PA P + PVM T VP
Sbjct: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVM-----TVVP 243
Query: 575 PPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIP 634
P + PPPV P P PPP+ AP PV PP+ +ATP P
Sbjct: 244 PQPLQT------PPPVPPQPQ----------PPPA---PAPQPVQSHPPIIAATPQPVKT 284
Query: 635 PPGV--------PQGIPPQLTAAPVPP-ASSSQSSQVPEKPRPALLPTPVSFGSAPPTTY 685
GV P I P +PP +++ Q E RP P P +
Sbjct: 285 KKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKK----DVPDSQQ 340
Query: 686 HP-PLQSAGPSEQV 698
HP P +S+ SEQ+
Sbjct: 341 HPAPEKSSKVSEQL 354
Score = 53.9 bits (128), Expect = 2e-06
Identities = 67/259 (25%), Positives = 88/259 (33%), Gaps = 100/259 (38%)
Query: 1481 SEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPP--------------PPMGKPPGSIV 1526
S P + + LP Q SR N ++ PP RPP PPM +PP ++
Sbjct: 858 SPPALHNALPQQPSRPSNRAAAL----PPKPARPPAVSPALTQTPLLPQPPMAQPPQVLL 913
Query: 1527 R---PSAPPARS--------SVPVTRPPVPIPPP-----PPPPPLPPPP-PVIKPQTSAV 1569
P APP S + +PP P+ P PPPPLPPPP P ++ Q
Sbjct: 914 EDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQ-- 971
Query: 1570 EQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPV------ 1623
+ P P PPP PPP PV
Sbjct: 972 ----------------------------QQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQ 1003
Query: 1624 ----------PMGM-----PPMSKPPP-----VQQTVDYGHGRDISTNKVEQIPYGE-RI 1662
P G PP +PPP QQ + + H S + PY +
Sbjct: 1004 FSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHH----SPRHHKSDPYSTGHL 1059
Query: 1663 TLRPDPL----PERSTFET 1677
P PL P+ S F++
Sbjct: 1060 REAPSPLMIHSPQMSQFQS 1078
Score = 50.4 bits (119), Expect = 2e-05
Identities = 65/257 (25%), Positives = 95/257 (36%), Gaps = 55/257 (21%)
Query: 1412 RHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKE 1471
+ P AE + SS+M G +S + E+ K+ ++ REQK+
Sbjct: 678 KRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKK 737
Query: 1472 QL----QKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVR 1527
Q+M+ + PPQ+ P PPP + PPP PP S+ +
Sbjct: 738 HHHHHHQQMQQAPAPVPQQPPPPPQQ---------PPPPPPPQQQQQPPP-PPPPPSMPQ 787
Query: 1528 PSAPPARSS--------VPVTRPPVP----------------IPPPPPPPPLPPPPPVIK 1563
+AP +SS VPV P +P +P P PP LP PP
Sbjct: 788 QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHST 847
Query: 1564 P----QTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPP 1619
P Q + V L + +Q S + AA+P P PP +
Sbjct: 848 PPHLNQHAVVSPP--------ALHNALPQQ--PSRPSNRAAALPPKPARPPAVSPALTQT 897
Query: 1620 PGPVPMGMPPMSKPPPV 1636
P + PPM++PP V
Sbjct: 898 P---LLPQPPMAQPPQV 911
Score = 48.5 bits (114), Expect = 7e-05
Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 29/172 (16%)
Query: 1482 EPQMADHLP-PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVT 1540
+P++ HLP P E ++ + PP + P P + R +A P + +
Sbjct: 832 QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSN--RAAALPPKPA---- 885
Query: 1541 RPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETA 1600
RPP P P LP PP PQ +E E + Q L + + T
Sbjct: 886 RPPAVSPALTQTPLLPQPPMAQPPQV-LLEDEEPPAPPLTSMQMQLYLQQL-QKVQPPTP 943
Query: 1601 AIPSA-------PVLPPPPVHSSI-------PPPGPVPMGMPPMSKPPPVQQ 1638
+PS P LPPPP H S+ PPP P PP +PPP QQ
Sbjct: 944 LLPSVKVQSQPPPPLPPPP-HPSVQQQLQQQPPPPP-----PPQPQPPPQQQ 989
Score = 47.8 bits (112), Expect = 1e-04
Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 6/108 (5%)
Query: 1461 QELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGK 1520
Q+L+ ++ L +K S+P PP S Q +P PPP PP +
Sbjct: 933 QQLQKVQPPTPLLPSVK-VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ 991
Query: 1521 PPGSIVRPSAPPARSSVPVTRPPVPI--PPPPPPP-PLPPPPPVIKPQ 1565
PP V P + S + +PP P PP PPP PPPP KPQ
Sbjct: 992 PPPRPVH--LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQ 1037
Score = 45.1 bits (105), Expect = 8e-04
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 12/127 (9%)
Query: 1445 VMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPG 1504
++++++ ++ L+ EL E + + + K G + P S + NT+
Sbjct: 146 IVLMAEALEKLFLQKINELPT-EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQAS- 203
Query: 1505 MYPPPGSYRP---PPPMGKPPGSIVRPSAPP---ARSSVPVTRPPVPIPPPPPPPPLPPP 1558
PP + P PPP+ P P+ P ++ V PP P+ PPP PP P P
Sbjct: 204 --TPPQTQTPQPNPPPVQATPHPF--PAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP 259
Query: 1559 PPVIKPQ 1565
PP PQ
Sbjct: 260 PPAPAPQ 266
Score = 43.9 bits (102), Expect = 0.002
Identities = 69/298 (23%), Positives = 99/298 (33%), Gaps = 33/298 (11%)
Query: 13 HYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
H PP PPPP A P+ +S + P S+G HL + +H QM
Sbjct: 1021 HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTG-------HLREAPSPLMIHSPQM 1073
Query: 73 -QCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQ 131
Q H PP P QP P L K+++ H +
Sbjct: 1074 SQFQSLTHQSPPQQNVQPKKQELRAASVVQPQP----------LVVVKEEKI-HSPIIRS 1122
Query: 132 RDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQP-S 190
P L P E PES P ++P P P PP + P PP P
Sbjct: 1123 EPFSPSLRP-EPPKHPESIKAP--VHLPQRPEMKPVDVGRPVIRPPEQNAP--PPGAPDK 1177
Query: 191 PSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS--------RPSQGHSKS 242
Q ++ +AP + S + L PSS A S R ++ +
Sbjct: 1178 DKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEER 1237
Query: 243 QLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQ 300
+ K ++QE + S + EQ + A E Q+QQ+ +Q
Sbjct: 1238 EKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQ 1295
Score = 40.8 bits (94), Expect = 0.014
Identities = 29/108 (26%), Positives = 41/108 (37%), Gaps = 13/108 (12%)
Query: 81 LPPPPL-PPPPVMPGGGYGDWQPPPPPMPPPP-----GPALSYQKQQQYKHQMLHHQRDG 134
+PP PL PPPV P QP PPP P P P ++ Q + + + D
Sbjct: 242 VPPQPLQTPPPVPP-------QPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADT 294
Query: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQP 182
+ PP PP P + + + P +PP P + P
Sbjct: 295 TTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHP 342
Score = 39.3 bits (90), Expect = 0.042
Identities = 55/213 (25%), Positives = 72/213 (33%), Gaps = 53/213 (24%)
Query: 1484 QMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPP 1543
Q + LP +E+ + ++ G R KP S V P+ A S+ P T+ P
Sbjct: 159 QKINELPTEETEIMIVQAKGR-----GRGRKETGTAKPGVSTV-PNTTQA-STPPQTQTP 211
Query: 1544 VPIPPP--PPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAA 1601
P PPP P P P P + QT +
Sbjct: 212 QPNPPPVQATPHPFPAVTPDLIVQTPVM------------------------------TV 241
Query: 1602 IPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQT-----VDYGHGRDISTNKVEQI 1656
+P P+ PPPV P P P P P S PP + T G R T I
Sbjct: 242 VPPQPLQTPPPVPPQ-PQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
Query: 1657 -PYGERITLRPDPLPERSTFETEHAGQRDRYDR 1688
P E +L P+P +T GQR R
Sbjct: 301 DPIHEPPSLPPEP-------KTTKLGQRRESSR 326
Score = 38.9 bits (89), Expect = 0.055
Identities = 49/189 (25%), Positives = 61/189 (32%), Gaps = 62/189 (32%)
Query: 101 QPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPP 160
QP PPP+ P P P + P + P VPP P
Sbjct: 212 QPNPPPVQATPHPF---------------------PAVTPDLIVQTPVMTVVPP----QP 246
Query: 161 SQSYMPPPQPPPSYYPPTSSQPYLPPAQ-PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLS 219
Q+ PPP PP QP PPA P P QS P P P + +
Sbjct: 247 LQT--PPPVPP---------QPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK---- 291
Query: 220 HSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTT------VQQEPLESGAKNKS 273
+ +P+ H PPS PP KTT P++ K+
Sbjct: 292 -------ADTTTPTTIDPIHE--------PPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
Query: 274 TEQQQAAPE 282
QQ APE
Sbjct: 337 DSQQHPAPE 345
Score = 33.9 bits (76), Expect = 1.8
Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 5/58 (8%)
Query: 320 PVVAKDTPEPVKEE---VTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374
PV A P P V P + VP P PP+PP + PPP P +P P
Sbjct: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPP--QPQPPPAPAPQPVQSHP 272
Score = 33.1 bits (74), Expect = 3.0
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 17/105 (16%)
Query: 1462 ELKMLREQKEQLQKMKDFGSEPQMADHLPPQ------ESRLQNTSSRPGMYPPPGSYRPP 1515
+ + L Q Q ++ E + A + PQ E ++ + R + P S RP
Sbjct: 1075 QFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP--SLRPE 1132
Query: 1516 PPMGKPPGSIVRPSAPPARSSV-------PVTRPPVPIPPPPPPP 1553
PP K P SI P P R + PV RPP PPP P
Sbjct: 1133 PP--KHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAP 1175
Score = 32.0 bits (71), Expect = 6.7
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Query: 335 TVPATSQVPESPSSEEP-PLPPPNEEVPPPLPPEEP 369
TVP T+Q P ++ P P PPP + P P P P
Sbjct: 195 TVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTP 230
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 103 bits (256), Expect = 2e-21
Identities = 89/242 (36%), Positives = 103/242 (42%), Gaps = 39/242 (16%)
Query: 517 PPPFVPYSQMPPPLPTMPP-PVLPPSLPPP--VMPPALPATVPPPGM----PPPVMPPSL 569
PPP P Q PP P PP P PP PPP V+PP L PP PPPV+ P
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAG---PPNRGDRPPPPVLFPGQ 282
Query: 570 PTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPP------PVMPL-P 622
P PP GP P PPP + GPPP PPP PP P PL P
Sbjct: 283 PFGQPP---------LGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGP 333
Query: 623 PLSSATPP--PGIPPPGVPQGIPPQLTAAPVPPASS---SQSSQVPEKPRPALLPTPVSF 677
PL+ A PP PG PPPG P P A PP +S + S+ P P P P
Sbjct: 334 PLTLAPPPHLPG-PPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDR 392
Query: 678 GSAPP-----TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPIT 732
G P T PL A E +N +S SA+ S SD G+ +A +T
Sbjct: 393 GDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAI--SRAVSDASAGDYGSAIETLVT 450
Query: 733 AV 734
A+
Sbjct: 451 AI 452
Score = 79.3 bits (194), Expect = 4e-14
Identities = 59/192 (30%), Positives = 70/192 (36%), Gaps = 16/192 (8%)
Query: 82 PPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPM 141
PPPP P P G PP PP PPPPG L R PP L P
Sbjct: 226 PPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL----PPPLAGPPNRGDRPPPPVLFPG 281
Query: 142 ELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYL 201
+ P P+PPG PP Y PPP PPP P PP P P P + L
Sbjct: 282 QPFGQPPLGPLPPGP-PPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLT---L 337
Query: 202 APTPSYSSSSSSSQSYLSHSQSYL---PSSQASPSRPSQGHSKSQLLAPPPP-----SAP 253
AP P + H P++ P+ S+G + PPP P
Sbjct: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGP 397
Query: 254 PGNKTTVQQEPL 265
PG + + PL
Sbjct: 398 PGREMDTARTPL 409
Score = 72.8 bits (177), Expect = 3e-12
Identities = 57/156 (36%), Positives = 62/156 (39%), Gaps = 33/156 (21%)
Query: 558 PGMPPPVMPPSLPTSVPPPGMPPSLSSAGPP-PVLPPPSLSSAGPPPVLPPPSLSSTAPP 616
PG PPP P PP G P GPP P PPP PPP+ PP+ PP
Sbjct: 223 PGGPPPPFPAGQTPPRPPLGPP------GPPGPPGPPPPGQVL-PPPLAGPPNRGDRPPP 275
Query: 617 PVM---------PLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPR 667
PV+ PL PL PPP +P G P G PP P PP P PR
Sbjct: 276 PVLFPGQPFGQPPLGPLPPGPPPP-VPGYGPPPGPPPPQQGPPPPPG--------PFPPR 326
Query: 668 PALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAP 703
P P P+ PP T PP GP AP
Sbjct: 327 P---PGPL----GPPLTLAPPPHLPGPPPGAPPPAP 355
Score = 70.9 bits (172), Expect = 1e-11
Identities = 85/300 (28%), Positives = 115/300 (38%), Gaps = 57/300 (19%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYP-PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTR 1541
P D PP +P + P PPG P P G PPG PP R
Sbjct: 267 PNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR 326
Query: 1542 PPVPIPPP---PPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSE 1598
PP P+ PP PPP LP PPP P V + + G+ T+D +G
Sbjct: 327 PPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGM-PTSDSRG-------- 377
Query: 1599 TAAIPSAPVLPPPPV-HSSIPPPG-PVPMGMPPMSK--------------PPPVQQTV-- 1640
P+ P PPP PPG + P+S+ + + V
Sbjct: 378 --PPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSAISRAVSD 435
Query: 1641 ----DYGHGRD-----ISTNKVEQIPYGERITLRPDPLPE-RSTFETEHAGQRDRYDRER 1690
DYG + IS K ++ +R + L + E++ G R +R R
Sbjct: 436 ASAGDYGSAIETLVTAISLIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSR 495
Query: 1691 DREPYFDRQ------SNVIADHRDF----KRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740
+R+ R+ S H D+ R+RE HRDRDRDR D +RDR +RE R R
Sbjct: 496 ERDHSRSREKSRRHKSRSRDRHDDYYRERSRERERHRDRDRDR---DRERDR-EREYRHR 551
Score = 70.1 bits (170), Expect = 2e-11
Identities = 65/207 (31%), Positives = 74/207 (35%), Gaps = 33/207 (15%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
P PP PPPP LP GP P G Q
Sbjct: 247 PGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPG-----------------------QP 283
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPM---PPPPGPALSYQKQQQYKHQML--- 128
QP P PP PPPPV GYG PPPP PPPPGP L
Sbjct: 284 FGQPPLGPLPPGPPPPV---PGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPP 340
Query: 129 HHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPA- 187
H PPG P P P P S MP S S PPP P PP Y PP
Sbjct: 341 PHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGR 400
Query: 188 QPSPSQSPPSQSYLAPTPSYSSSSSSS 214
+ +++P S++ + + + SSS
Sbjct: 401 EMDTARTPLSEAEFEEIMNRNRAISSS 427
Score = 55.8 bits (133), Expect = 4e-07
Identities = 82/313 (26%), Positives = 108/313 (34%), Gaps = 76/313 (24%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP 1542
P LPP + N RP PPP + P P G+PP + P PP VP P
Sbjct: 253 PPPGQVLPPPLAGPPNRGDRP---PPPVLF-PGQPFGQPPLGPLPPGPPPP---VPGYGP 305
Query: 1543 PVPIPPP---PPPPPLP----PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEF 1595
P PPP PPPPP P PP P+ P T A L
Sbjct: 306 PPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPH------------------LPGPP 347
Query: 1596 KSETAAIPSA-PVLPPPPVHSSIPPP---GPVPMGMPPMSKPPPVQQTVDYG-HGRDIST 1650
P P PPP +S +P GP P P +PPP + DYG GR++ T
Sbjct: 348 PGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPP--TDPYGRPPPYDRG-DYGPPGREMDT 404
Query: 1651 NKV-------EQI----------------------PYGERITLRPDPLPERSTFETEHAG 1681
+ E+I YG I + S +
Sbjct: 405 ARTPLSEAEFEEIMNRNRAISSSAISRAVSDASAGDYGSAIETLVTAI---SLIKQSKVS 461
Query: 1682 QRDR----YDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRER 1737
DR +D + +S R+ R+R+ R R++ R RDR D
Sbjct: 462 ADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSRSRDRHDDYY 521
Query: 1738 RPRDDRAQSYRDK 1750
R R + +RD+
Sbjct: 522 RERSRERERHRDR 534
Score = 54.3 bits (129), Expect = 1e-06
Identities = 45/143 (31%), Positives = 52/143 (36%), Gaps = 19/143 (13%)
Query: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVI 1562
PG P + P G PP PP RPP+ PP PP PP PPPP +
Sbjct: 208 PGAVPGGDRFPGPAGPGGPPPPFPAGQTPP--------RPPLG-PPGPPGPPGPPPPGQV 258
Query: 1563 KPQTSAVEQERWDEDSFYGLWDTND--EQGLNSEFKSETAAIPS--APVLPPPPVHSSIP 1618
P A R D L+ + L +P P PPPP P
Sbjct: 259 LPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPP 318
Query: 1619 PPGPV------PMGMPPMSKPPP 1635
PPGP P+G P PPP
Sbjct: 319 PPGPFPPRPPGPLGPPLTLAPPP 341
Score = 52.0 bits (123), Expect = 6e-06
Identities = 52/177 (29%), Positives = 62/177 (35%), Gaps = 36/177 (20%)
Query: 1477 KDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMG-----KPPGSI------ 1525
K F S+ +M Q ++ PP GS R P G + PG++
Sbjct: 161 KQFLSQFEMQSRKTTQSGQMSGEGKAG---PPGGSSRAAFPQGGRGRGRFPGAVPGGDRF 217
Query: 1526 ---VRPSAPPARSSVPVTRPPVPIPPPPPPPPL-PPPPPVIKPQTSAVEQERWDEDSFYG 1581
P PP T P P+ PP PP P PPPP + P A R D
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277
Query: 1582 LWDTNDEQGLNSEFKSETAAIP---SAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
L F + P P PPPPV PPPGP P P PPP
Sbjct: 278 L------------FPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPP---PQQGPPPP 319
Score = 39.7 bits (91), Expect = 0.032
Identities = 68/295 (23%), Positives = 76/295 (25%), Gaps = 139/295 (47%)
Query: 88 PPPVMPGGGYGDWQPPPPPMPP---PPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELE 144
P P PGG PPPP P PP P L GPPG
Sbjct: 218 PGPAGPGG-------PPPPFPAGQTPPRPPL------------------GPPG------- 245
Query: 145 SPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT 204
PP PPG PP +PPP P P L P QP PP L P
Sbjct: 246 -----PPGPPGP--PPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQ--PP----LGPL 292
Query: 205 PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEP 264
P P P G+ PPP PP
Sbjct: 293 PP------------------------GPPPPVPGYG-------PPPGPPP---------- 311
Query: 265 LESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAK 324
Q P P P P+
Sbjct: 312 ------------PQQGPPPPPGPFPPRP-------------------------------- 327
Query: 325 DTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDAR 379
P P+ +T+ +P P P PPP V P P S P D+R
Sbjct: 328 --PGPLGPPLTLAPPPHLPGPP----PGAPPPAPHVNPAFFPPPTNSGMPTSDSR 376
Score = 35.4 bits (80), Expect = 0.61
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 4/65 (6%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPT 571
G + P P +P P P PPP P + P PP + +P P PP+ P
Sbjct: 329 GPLGPPLTLAPPPHLPGPPPGAPPPA--PHVNPAFFPPPTNSGMPTSDSRGP--PPTDPY 384
Query: 572 SVPPP 576
PPP
Sbjct: 385 GRPPP 389
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 100 bits (250), Expect = 1e-20
Identities = 70/259 (27%), Positives = 102/259 (39%), Gaps = 41/259 (15%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPP 576
P P + + PPP T PP+ + PPP P+ P T P P P PP+ T+ PPP
Sbjct: 1438 PSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTP-SPPTTTTTTPPP 1496
Query: 577 GM-----------PPSLSSAGPPPVLP-PPSLSSAGPPPV----------LPPPSLSSTA 614
PP+ ++ PP P PP+ ++ PPP + PP+ ++T
Sbjct: 1497 TTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL 1556
Query: 615 PPPVMPLPPLSSATPPPGIPPPGVPQGI---PPQLTAAPVPPASSSQS----------SQ 661
PP P PP ++ T PP P P PP +T PP ++ +
Sbjct: 1557 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT 1616
Query: 662 VPEKPRPALLPTPVSFGSAPPTT--YHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQG 719
P P + P S + PPTT PP + P P + + P + ++
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP- 1675
Query: 720 LGESSAAPSQPITAVKDMP 738
+ PS PIT P
Sbjct: 1676 --PPTTTPSSPITTTPSPP 1692
Score = 97.8 bits (242), Expect = 1e-19
Identities = 63/205 (30%), Positives = 86/205 (41%), Gaps = 19/205 (9%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPP 576
PP P + PP T PP PS PP P T P P PP++ T+ PPP
Sbjct: 1541 PPTTTPIT--PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPP 1598
Query: 577 ---GMPPSLSSAGPPPVLPPPSLSSAGPPPVLP--PPSLSSTAPPPVMPLPPLSSATPPP 631
PP+ ++ PPP P PP P PP+ ++T PP P PP ++ T PP
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTP------SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1652
Query: 632 GIPPPGVPQGIPPQ--LTAAPVPPASSSQSSQVPEKPRP----ALLPTPVSFGSAPPTTY 685
P P P +T PP +++ SS + P P P+P + S+P TT
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712
Query: 686 HPPLQSAGPSEQVNSKAPLSKSALP 710
P + PS + S + P
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTP 1737
Score = 96.7 bits (239), Expect = 2e-19
Identities = 71/245 (28%), Positives = 98/245 (40%), Gaps = 30/245 (12%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMP--PALPATVPPPGMPPPVMPPSLPTSVPPPGMPP---- 580
PP PPP +LPP P P T PPP P PP T+ PPP P
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTP--SPPITTTTTPPPTTTPSPPI 1458
Query: 581 SLSSAGPPPVLPPPSLSSAGPPPVLP-PPSLSSTAPPP-VMPLPPLSSATPPPG----IP 634
S ++ PP P P ++ PP P PP+ ++T PPP P PP ++ PP +P
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518
Query: 635 PPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTT--YHPPLQSA 692
P P PP T PP ++ P P + P S + PPTT PP +
Sbjct: 1519 PTTTPS--PPTTTTTTPPPTTT------PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 693 GPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSS 752
P P + + P + ++ + PS P T P + P PP ++
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTP---PPTTTPSPPTTTTTTPPPTT---TPSPPTTT 1624
Query: 753 YLESP 757
+ P
Sbjct: 1625 PITPP 1629
Score = 96.7 bits (239), Expect = 2e-19
Identities = 80/284 (28%), Positives = 113/284 (39%), Gaps = 50/284 (17%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALP---ATVPPPGMPPPVMPPSLPTSV 573
PPP + PP T PP + PPP P+ P T PPP P PP T+
Sbjct: 1408 PPP--TSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS--PPISTTTT 1463
Query: 574 PPPGMPPS--LSSAGPPPVLP-PPSLSSAGPPPV----------LPPPSLSSTAPPPVMP 620
PPP PS ++ PP P PP+ ++ PPP + PP+ ++T PP P
Sbjct: 1464 PPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTP 1523
Query: 621 LPPLSSATPPP-----------GIPPPGVPQGIPPQLTAAP------VPPASSSQSSQVP 663
PP ++ T PP I PP +PP T +P PP +++ S
Sbjct: 1524 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT 1583
Query: 664 EKPRPALLPT---PVSFGSAPP---TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSD 717
P P + T P + +PP TT PP + P P S + LP ++ S
Sbjct: 1584 TTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1643
Query: 718 QGLGES----SAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESP 757
+ + PS P T P+ + PP ++ SP
Sbjct: 1644 PPTTTTTPPPTTTPSPPTTTTPSPPITT---TTTPPPTTTPSSP 1684
Score = 96.7 bits (239), Expect = 2e-19
Identities = 76/271 (28%), Positives = 105/271 (38%), Gaps = 36/271 (13%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGM-----PPPVMPPSLPT 571
P P + PPP T PP P PP P T P P PPP PS PT
Sbjct: 1484 PSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPT 1543
Query: 572 SVPPPGMPPSLSSAGPPPVLP-PPSLSSAGPPPVL----------PPPSLSSTAPPP-VM 619
+ P PP+ ++ PP P PP ++ PPP PP++++T PPP
Sbjct: 1544 TTPIT--PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601
Query: 620 PLPPLSSATPPP-----------GIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRP 668
P PP ++ T PP I PP +PP T +P P +++ P
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661
Query: 669 ALLPTP--VSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAA 726
P+P + + PPTT + PS + S + P S ++ S+
Sbjct: 1662 TTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTT-TPSSTTT 1720
Query: 727 PSQPITAVKDMPVRSGGLLPDPPRSSYLESP 757
PS P T M S P PP ++ P
Sbjct: 1721 PSPPPTT---MTTPSPTTTPSPPTTTMTTLP 1748
Score = 88.6 bits (218), Expect = 6e-17
Identities = 65/219 (29%), Positives = 91/219 (41%), Gaps = 30/219 (13%)
Query: 515 SMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMP--PALPATVPPPGMPPPVMPPSLPTS 572
++PP P PP T PPP PS P P P + T PPP P PP+ T+
Sbjct: 1555 TLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS--PPTTTTT 1610
Query: 573 VPPPGMPPSLSSAGP----------PPVL---PPPSLSSAGPPPVLP-PPSLSSTAPP-- 616
PPP PS + P PP PPP+ ++ PP P PP+ ++ +PP
Sbjct: 1611 TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT 1670
Query: 617 -PVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPP--ASSSQSSQVPEKPRPALLPT 673
P P + ++P P P P T P P +++ SS P P + T
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT 1730
Query: 674 PVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYS 712
P +P TT PP + + +PL+ + LP S
Sbjct: 1731 P-----SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764
Score = 85.1 bits (209), Expect = 7e-16
Identities = 57/200 (28%), Positives = 81/200 (40%), Gaps = 35/200 (17%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVM---PPALPATVPPPGMPP------PVMPP 567
PPP S PP T PP + + PPP PP T PPP P P+ PP
Sbjct: 1572 PPPTTTPS--PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1629
Query: 568 SLPTSVPP---PGMPPSLSSAGPPPVLPPPSLSSAGPPPVL----PPPSLSSTAPPPVMP 620
+ T++PP P PP+ ++ PP P P ++ PP+ PPP+ + ++P P
Sbjct: 1630 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689
Query: 621 LPPLSSATPPPGIPPPGVP------------QGIPPQLTAAPVP-----PASSSQSSQVP 663
PP ++ T P P P PP P P P +++ ++ P
Sbjct: 1690 SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749
Query: 664 EKPRPALLPTPVSFGSAPPT 683
L TP+ PPT
Sbjct: 1750 TTTSSPLTTTPLPPSITPPT 1769
Score = 76.6 bits (187), Expect = 2e-13
Identities = 84/383 (21%), Positives = 124/383 (32%), Gaps = 82/383 (21%)
Query: 15 PPPPVPPPPPVAL-----PEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69
PPP P PP+ P +P P S++TTP ++
Sbjct: 1432 PPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPS-------------------- 1471
Query: 70 KQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLH 129
PP P PP PPP P P + +
Sbjct: 1472 ------------PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPP 1519
Query: 130 HQRDGPPGLV-----PMELESPPESPPVPPGSY---MPPSQSYMPPPQ----PPPSYYP- 176
PP P SPP + P+ P + +PP+ + PPP PPP+ P
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1579
Query: 177 -PTSSQPYLPPAQ-----PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQA 230
PT++ P P P+ + SPP+ + P P+ + S ++ + +
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1639
Query: 231 SPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQA----APEPDPS 286
+PS P + PPP + P TT P+ + T + P P +
Sbjct: 1640 TPSPPP-----TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTT 1694
Query: 287 TMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESP 346
TMT T P + TP P +T P+ + P P
Sbjct: 1695 TMTTPSPT--------------TTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPP 1740
Query: 347 SSEEPPLPPPNEEVP---PPLPP 366
++ LPP P PLPP
Sbjct: 1741 TTTMTTLPPTTTSSPLTTTPLPP 1763
Score = 75.5 bits (184), Expect = 5e-13
Identities = 95/389 (24%), Positives = 128/389 (32%), Gaps = 86/389 (22%)
Query: 15 PPPPVPPPPPVAL----PEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQK 70
PP P PPP + P +P P +++TTP
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPP--------------------------- 1433
Query: 71 QMQCVLQPHHLPPPPL-----PPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKH 125
P P PP+ PPP P PPP P P P +
Sbjct: 1434 -------PTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSP-PTTTPSPPTTTPS 1485
Query: 126 QMLHHQRDGPPGLVPMELESPPESPPV-PPGSY--MPPSQSYMPPPQ----PPPSYYP-P 177
PP P SPP + P+ PP S +PP+ + PP PPP+ P P
Sbjct: 1486 PPTTTTTTPPPTTTP----SPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSP 1541
Query: 178 TSSQPYLPPAQ-----PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS-QSYLPSSQAS 231
++ P PP P+ + SPP + P P+ + S ++ + + + P +
Sbjct: 1542 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601
Query: 232 PSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMT-- 289
PS P+ PPP+ P TT P S +T P P P+T T
Sbjct: 1602 PSPPTT------TTTTPPPTTTPSPPTTTPITPPTS----TTTLPPTTTPSPPPTTTTTP 1651
Query: 290 PQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPES---- 345
P S T P TP P +T P+ + P S
Sbjct: 1652 PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITT 1711
Query: 346 ---PSSEEPPLPPPNEEVPP-----PLPP 366
PSS P PPP P P PP
Sbjct: 1712 TTTPSSTTTPSPPPTTMTTPSPTTTPSPP 1740
Score = 67.0 bits (162), Expect = 2e-10
Identities = 41/137 (29%), Positives = 56/137 (40%), Gaps = 6/137 (4%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPP 576
PPP S PP T PP+ + PPP P+ P T P + PS T+ P
Sbjct: 1651 PPPTTTPS--PPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP 1708
Query: 577 GMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPP 636
+ S+ P PP ++++ P PP+ + T PP PL++ PP I PP
Sbjct: 1709 ITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPP 1768
Query: 637 GVPQGIPPQLTAAPVPP 653
P T P P
Sbjct: 1769 ----TFSPFSTTTPTTP 1781
Score = 65.9 bits (159), Expect = 4e-10
Identities = 67/252 (26%), Positives = 96/252 (38%), Gaps = 43/252 (17%)
Query: 515 SMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVP 574
++PP P PP T PPP PS PP P+ P T PPP PS P +
Sbjct: 1634 TLPPTTTP--SPPPTTTTTPPPTTTPS-PPTTTTPSPPITTTTT--PPPTTTPSSPITTT 1688
Query: 575 PPGMPPSLSSAGPPPVLPPPS-----------LSSAGPPPVLPPPSLSSTAPPP---VMP 620
P PP+ + P P P S + + PP + PS ++T PP +
Sbjct: 1689 PS--PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT 1746
Query: 621 LPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSA 680
LPP ++++P P +PP +T PP S S+ P P L S
Sbjct: 1747 LPPTTTSSPLTTTP-------LPPSIT----PPTFSPFSTTTPTTPCVPLCNWTGWLDSG 1795
Query: 681 PPTTYHPPLQSAGPSEQVNS------KAPLSKSALPYSSFSSDQGLGESSAAPSQPITAV 734
P + P G +E + A +S A Y Q LG++
Sbjct: 1796 KPNFHKP----GGDTELIGDVCGPGWAANISCRATMYPDVPIGQ-LGQTVVCDVSVGLIC 1850
Query: 735 KDMPVRSGGLLP 746
K+ + GG++P
Sbjct: 1851 KNEDQKPGGVIP 1862
Score = 65.1 bits (157), Expect = 7e-10
Identities = 52/213 (24%), Positives = 76/213 (35%), Gaps = 48/213 (22%)
Query: 578 MPPSLSSAGPPPVLP-----------------PPSLSSAGPPPVL---PPPSLSSTAPPP 617
M +++ PP P PP+ ++ PPP PP + ++T PP
Sbjct: 1392 MDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPT 1451
Query: 618 VMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQS---SQVPEKPRPALLPTP 674
P PP+S+ T PP P P P T P PP +++ + + P P + P
Sbjct: 1452 TTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1511
Query: 675 VSFGSAPP----------TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESS 724
S + PP TT PP + P P S + LP +
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP------------PT 1559
Query: 725 AAPSQPITAVKDMPVRSGGLLPDPPRSSYLESP 757
PS P T P + P PP ++ P
Sbjct: 1560 TTPSPPPTTTTTPPPTT---TPSPPTTTTPSPP 1589
Score = 63.9 bits (154), Expect = 2e-09
Identities = 72/298 (24%), Positives = 106/298 (35%), Gaps = 46/298 (15%)
Query: 15 PPPPVPPPPPVALPEASPGPGYS--SSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
PPP P PP P P + +TTP+ P+++ +
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTP-PPTTTPSPPTTTPITPPTS 1552
Query: 73 QCVLQPHHLPPPP-----LPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQM 127
L P P PP PPP P PP P PP +
Sbjct: 1553 TTTLPPTTTPSPPPTTTTTPPPTTTPS-------PPTTTTPSPPTITTTTPPPTTTPSPP 1605
Query: 128 LHHQRDGPPGLVPMELESPPESPPVPPGSY---MPPSQSYMPPPQ----PPPSYYP--PT 178
PP P SPP + P+ P + +PP+ + PPP PPP+ P PT
Sbjct: 1606 TTTTTTPPPTTTP----SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661
Query: 179 SSQPYLP---PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS---QSYLPSSQASP 232
++ P P P P+ +P S P+P ++ ++ S + S + PSS +P
Sbjct: 1662 TTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTP 1721
Query: 233 SRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTP 290
S P + + P P + P TT+ P +T P P ++TP
Sbjct: 1722 SPP-----PTTMTTPSPTTTPSPPTTTMTTLP-------PTTTSSPLTTTPLPPSITP 1767
Score = 63.2 bits (152), Expect = 3e-09
Identities = 63/261 (24%), Positives = 88/261 (33%), Gaps = 32/261 (12%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 4027 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4086
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 4087 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4146
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFG--SAPP-------- 682
P P T P P + + P + PTP G + PP
Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI 4206
Query: 683 ---TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPV 739
TT +PP +S+ P ++ +PL++S S+ + S+A PS P
Sbjct: 4207 AELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM-TSTAPPSTPTAPT----T 4261
Query: 740 RSGGLLPDPPRSSYLESPRGP 760
SGG PP S+ P P
Sbjct: 4262 TSGGHTLSPPPSTTTSPPGTP 4282
Score = 59.7 bits (143), Expect = 3e-08
Identities = 66/289 (22%), Positives = 90/289 (31%), Gaps = 76/289 (26%)
Query: 81 LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140
LPP P PP PPP P PP +
Sbjct: 1416 LPPTTTPSPPTTT-----TTTPPPTTTPSPP---------------------------IT 1443
Query: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200
PP + P PP S + PPP PS PPT++ P+ P+ + SPP+ +
Sbjct: 1444 TTTTPPPTTTPSPP-----ISTTTTPPPTTTPS--PPTTT-----PSPPTTTPSPPTTTT 1491
Query: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV 260
P P+ + S ++ + + +PS P + PPP+ P TT
Sbjct: 1492 TTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPP------TTTTTTPPPTTTPSPPTTT 1545
Query: 261 QQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGP 320
P S +T P P P+T T P P
Sbjct: 1546 PITPPTS----TTTLPPTTTPSPPPTTTTTPP---------------------PTTTPSP 1580
Query: 321 VVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEP 369
TP P T P + P P++ PP PP P P
Sbjct: 1581 PTT-TTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1628
Score = 56.2 bits (134), Expect = 3e-07
Identities = 54/226 (23%), Positives = 77/226 (34%), Gaps = 22/226 (9%)
Query: 145 SPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT 204
SPP + P PP P S + +PP P PPT++ P P+ + SPP + P
Sbjct: 1400 SPPTTTPSPP----PTSTTTLPPTTTPS---PPTTTTTTPP---PTTTPSPPITTTTTPP 1449
Query: 205 PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS-KSQLLAPPPPSAPPGNKTTVQQE 263
P+ + S S + + +PS P+ S + PPP+ P TT
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT--- 1506
Query: 264 PLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVA 323
P+ A + P +T TP T P +
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPT--------TTPSPPTTTPITPPTSTTTLPP 1558
Query: 324 KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEP 369
TP P T P + P P++ P P PPP P
Sbjct: 1559 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP 1604
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 1957 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2016
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2017 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2076
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2077 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2128
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2026 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2085
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2086 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2145
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2197
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2095 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2214
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2215 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2266
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2164 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2223
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2224 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2283
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2284 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2335
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2293 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2352
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2353 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2302 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2361
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2431 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2490
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2491 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2559
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2569 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2628
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2629 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2578 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2697
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2698 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2767 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2716 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2776 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2835
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2836 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2904
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2905 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2854 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2914 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2973
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 2983 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3042
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3043 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 2992 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3111
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3180
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3181 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3130 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3189
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3190 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3249
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3250 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3259 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3318
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3319 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3268 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3328 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3387
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3388 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3456
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3457 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3406 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3465
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3466 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3525
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3526 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3475 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3535 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3594
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3595 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3604 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3663
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3664 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3673 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3732
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3733 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3784
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3682 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3742 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3801
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3802 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3853
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3751 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3810
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3811 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3870
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3871 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3922
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3820 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3939
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 3940 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3991
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3889 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 3949 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4008
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 4009 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4060
Score = 51.2 bits (121), Expect = 1e-05
Identities = 41/172 (23%), Positives = 54/172 (31%), Gaps = 14/172 (8%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 3958 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017
Query: 582 LSSAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
++ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 4018 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4077
Query: 636 PGVPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 4078 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4129
Score = 50.8 bits (120), Expect = 1e-05
Identities = 52/202 (25%), Positives = 69/202 (34%), Gaps = 28/202 (13%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP-----PVMPPSLPTSVPPPGMPPS 581
P P T P P + V P P P P V P PT P P
Sbjct: 4096 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4155
Query: 582 LSSAGPPPVLPPPSLSSAGPPPVL--------PPPSLSSTAPPP---VMPLPPLSSATPP 630
++ P P + P+ P P+ + T PP P+ L+++ PP
Sbjct: 4156 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPP 4215
Query: 631 PGIPPPGVPQGIPPQLT-----AAPVPPASSSQSSQVPEKPRPALLPTPVSFG---SAPP 682
P P + LT + +PPA S+ P P PT S G S PP
Sbjct: 4216 PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP---TAPTTTSGGHTLSPPP 4272
Query: 683 -TTYHPPLQSAGPSEQVNSKAP 703
TT PP + +S AP
Sbjct: 4273 STTTSPPGTPTRGTTTGSSSAP 4294
Score = 49.7 bits (117), Expect = 3e-05
Identities = 42/169 (24%), Positives = 54/169 (31%), Gaps = 46/169 (27%)
Query: 1481 SEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP-PGSIVRPSAPPARSSVPV 1539
S P PP + ++ P PPP + PPP P P + PS P ++ P
Sbjct: 1540 SPPTTTPITPPTSTTTLPPTTTPS--PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP- 1596
Query: 1540 TRPPVPIP---------PPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQG 1590
PP P PPP P PP I P TS
Sbjct: 1597 --PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS----------------------- 1631
Query: 1591 LNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639
T +P PPP ++ PPP P + PP+ T
Sbjct: 1632 --------TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT 1672
Score = 49.3 bits (116), Expect = 4e-05
Identities = 42/176 (23%), Positives = 58/176 (32%), Gaps = 23/176 (13%)
Query: 527 PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAG 586
P P T P P + V P T P G P P T+ P P+ + G
Sbjct: 4142 PTPTGTQTPTTTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG 4196
Query: 587 PPP---VLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPP----GIPPPGVP 639
PP P L+++ PPP P S + P+ L S PP PP P
Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP 4256
Query: 640 QGI-----------PPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
PP T +P + ++ P P+ + T + P T
Sbjct: 4257 TAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312
Score = 48.9 bits (115), Expect = 5e-05
Identities = 39/170 (22%), Positives = 53/170 (31%), Gaps = 9/170 (5%)
Query: 524 SQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLS 583
++ P P T P P P T P V P PT P P +
Sbjct: 1890 TENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1949
Query: 584 SAGPPPVLPPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPG 637
+ P P + P V P P+ + T P P+ ++ TP P
Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2009
Query: 638 VPQGIPPQLTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
P P T P P + + P + PTP G+ PTT
Sbjct: 2010 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2059
Score = 48.9 bits (115), Expect = 5e-05
Identities = 63/277 (22%), Positives = 103/277 (37%), Gaps = 40/277 (14%)
Query: 136 PGLVPMELESPPESPPVPPGSYMPPSQ------SYMPPPQPPPSYYPPTSSQPYLPPAQP 189
P P+ + P P G+ P + + P P P + P + P A+
Sbjct: 4150 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAEL 4209
Query: 190 SPSQSPPSQSYLAPTPSYSSSSSSSQSYLS-------HSQSYLPSSQASPSRPSQGHSKS 242
+ S PP S + S SS + S + LS + + PS+ +P+ S GH+
Sbjct: 4210 TTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHT-- 4267
Query: 243 QLLAPPP--PSAPPGNK---TTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYW 297
L+PPP ++PPG TT + + ++T P P P + TP +
Sbjct: 4268 --LSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS-TPSIIRTTG 4324
Query: 298 YRQH----LLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEV---------TVPATSQVPE 344
R + L+ + PG + DT V + + P+T
Sbjct: 4325 LRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTP 4384
Query: 345 SPSSEEP----PLPPPNEEVPPPLPPEEPQSEDPEED 377
+PS P P P++ P PPE P + P ++
Sbjct: 4385 TPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQE 4421
Score = 46.2 bits (108), Expect = 3e-04
Identities = 37/143 (25%), Positives = 44/143 (30%), Gaps = 15/143 (10%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTR----PPVPIPPPPPPPPLPPP---- 1558
PP + PPP P PS P S P T PP P PP P+ PP
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTT 1515
Query: 1559 --PPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSS 1616
PP P + T S T +P PPP ++
Sbjct: 1516 TLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS-----TTTLPPTTTPSPPPTTTT 1570
Query: 1617 IPPPGPVPMGMPPMSKPPPVQQT 1639
PPP P + PP T
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITT 1593
Score = 45.8 bits (107), Expect = 4e-04
Identities = 37/162 (22%), Positives = 51/162 (31%), Gaps = 14/162 (8%)
Query: 532 TMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVL 591
T P + + P P P T P P PT P P ++ P
Sbjct: 1880 TQPTTMTTTTTENPTPPTTTPITTTTTVTPTPT-----PTGTQTPTTTPITTTTTVTPTP 1934
Query: 592 PPPSLSSAGPPP------VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQ 645
P + P V P P+ + T P P+ ++ TP P P P
Sbjct: 1935 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 1994
Query: 646 LTAAPVP---PASSSQSSQVPEKPRPALLPTPVSFGSAPPTT 684
T P P + + P + PTP G+ PTT
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2036
Score = 44.7 bits (104), Expect = 0.001
Identities = 39/165 (23%), Positives = 51/165 (30%), Gaps = 8/165 (4%)
Query: 1481 SEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVT 1540
S P PP + ++ P P + PP PP + P S P T
Sbjct: 1485 SPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT 1544
Query: 1541 RPPVP------IPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSE 1594
P P +PP P P PP P T+ S + T
Sbjct: 1545 TPITPPTSTTTLPPTTTPSP-PPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPS 1603
Query: 1595 FKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639
+ T P P PP + I PP +PP + P P T
Sbjct: 1604 PPTTTTTTPPPTTTPSPPTTTPITPPTSTTT-LPPTTTPSPPPTT 1647
Score = 43.5 bits (101), Expect = 0.002
Identities = 36/135 (26%), Positives = 42/135 (31%), Gaps = 17/135 (12%)
Query: 1508 PPGSYRPPPPMGKP--PGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPL-PPPPPVIKP 1564
PP + P PP+ P PS P S P T P P PPP P PP P
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507
Query: 1565 QTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVP 1624
T T + T P P PP + I PP
Sbjct: 1508 ITPPAS-------------TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1554
Query: 1625 MGMPPMSKPPPVQQT 1639
+PP + P P T
Sbjct: 1555 T-LPPTTTPSPPPTT 1568
Score = 42.7 bits (99), Expect = 0.004
Identities = 38/162 (23%), Positives = 50/162 (30%), Gaps = 35/162 (21%)
Query: 1481 SEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARS--SVP 1538
S P PP + ++ P PP + PPP P I + PP + S P
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPS--PPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP 1457
Query: 1539 VTRPPVPIPPPPPPPPL-PPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKS 1597
++ P P P PP P PP P +
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPPTTTPSP-----------------------------PT 1488
Query: 1598 ETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639
T P P PP + I PP +PP + P P T
Sbjct: 1489 TTTTTPPPTTTPSPPTTTPITPPASTTT-LPPTTTPSPPTTT 1529
Score = 40.0 bits (92), Expect = 0.025
Identities = 66/273 (24%), Positives = 92/273 (33%), Gaps = 42/273 (15%)
Query: 517 PPPFVPYSQMPPPLPTMPPPV--LPPSLPPPVMPPALPATVPPPGMPPP-------VMPP 567
P P +Q PP T P+ L S PPP + P T P +PP
Sbjct: 4186 PTPTPTGTQTGPPTHTSTAPIAELTTSNPPP--ESSTPQTSRSTSSPLTESTTLLSTLPP 4243
Query: 568 SLP-TSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPP--PVLPPPSLSSTAPPPVMPLPPL 624
++ TS PP P + ++ L PP ++ PP P + SS+AP P
Sbjct: 4244 AIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 4303
Query: 625 SSA-TPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPT 683
+SA TP P P P + + P SS V G+ T
Sbjct: 4304 TSAWTPTP------TPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDT 4357
Query: 684 TYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGG 743
Y + E N P + S P S S+ + S+ PS+P K
Sbjct: 4358 CYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTP-SKPSSTPSKPTPGTK-------- 4408
Query: 744 LLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCE 776
P P FD PR+ + C+
Sbjct: 4409 ------------PPECPDFDPPRQENETWWLCD 4429
Score = 38.5 bits (88), Expect = 0.072
Identities = 50/209 (23%), Positives = 63/209 (30%), Gaps = 47/209 (22%)
Query: 15 PPPPVPPPPPVAL-----PEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69
PPP P PP P +P P +TTP P +S
Sbjct: 1596 PPPTTTPSPPTTTTTTPPPTTTPSP---PTTTPITPPTS--------------------- 1631
Query: 70 KQMQCVLQPHHLPPPP-----LPPPPVMPGGGYGDWQPPP-------PPMPPPPGPALSY 117
L P P PP PPP P PP PP P P +
Sbjct: 1632 ---TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT 1688
Query: 118 QKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMP-PPQPPPSYYP 176
+ S +P PP + PS + P PP + P
Sbjct: 1689 PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLP 1748
Query: 177 P-TSSQPYLPPAQPSPSQSPPSQSYLAPT 204
P T+S P P PS +PP+ S + T
Sbjct: 1749 PTTTSSPLTTTPLP-PSITPPTFSPFSTT 1776
Score = 37.4 bits (85), Expect = 0.16
Identities = 27/90 (30%), Positives = 34/90 (37%), Gaps = 12/90 (13%)
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVP-PPGMPPPVMPPS---- 568
M+ P P S P T P PS PP M P T P PP +PP+
Sbjct: 1696 MTTPSPTTTPSS-PITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSS 1754
Query: 569 ------LPTSVPPPGMPPSLSSAGPPPVLP 592
LP S+ PP P ++ P +P
Sbjct: 1755 PLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784
Score = 37.0 bits (84), Expect = 0.21
Identities = 49/245 (20%), Positives = 85/245 (34%), Gaps = 36/245 (14%)
Query: 136 PGLVPMELESPPESPPVPPGSYMPPSQ------SYMPPPQPP----PSYYPPTSSQPYLP 185
P P+ + P P G+ P + + P P P P+ P T++ P
Sbjct: 4081 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4140
Query: 186 PAQPSPSQSP-----PSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQG-- 238
P+ +Q+P + + + PTP+ + + + + + ++ + + P+ +P+ G
Sbjct: 4141 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTGTQTGPP 4198
Query: 239 -HSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKST----------EQQQAAPEPDPST 287
H+ + +A S PP +T Q S +ST E AP P+
Sbjct: 4199 THTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA 4258
Query: 288 MTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPS 347
T H LS T PG + P V TS +P+
Sbjct: 4259 PTTTS------GGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT 4312
Query: 348 SEEPP 352
P
Sbjct: 4313 PLSTP 4317
Score = 36.6 bits (83), Expect = 0.27
Identities = 46/246 (18%), Positives = 86/246 (34%), Gaps = 35/246 (14%)
Query: 135 PPGLVPMELESPPESPPVPPGSYMP------PSQSYMPPPQP----PPSYYPPTSSQPYL 184
PP P+ + P P G+ P + + P P P P+ P T++
Sbjct: 1895 PPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1954
Query: 185 PPAQPSPSQSP-----PSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGH 239
P P+ +Q+P + + + PTP+ + + + + + ++ + + P+ + ++
Sbjct: 1955 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ----- 2009
Query: 240 SKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYR 299
P + P TTV P +G + +T P +T+TP
Sbjct: 2010 --------TPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTPTGTQT 2056
Query: 300 QHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEE 359
+ T V G TP VT T ++P++ P+
Sbjct: 2057 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTV 2114
Query: 360 VPPPLP 365
P P P
Sbjct: 2115 TPTPTP 2120
Score = 36.2 bits (82), Expect = 0.36
Identities = 25/88 (28%), Positives = 32/88 (36%), Gaps = 15/88 (17%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSV---PVTRPPVPI 1546
PP + T++ P PP + PPP P I +PP + P T P PI
Sbjct: 1652 PPTTTPSPPTTTTPS--PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPI 1709
Query: 1547 P----------PPPPPPPLPPPPPVIKP 1564
P PPP + P P P
Sbjct: 1710 TTTTTPSSTTTPSPPPTTMTTPSPTTTP 1737
Score = 36.2 bits (82), Expect = 0.36
Identities = 59/295 (20%), Positives = 92/295 (31%), Gaps = 66/295 (22%)
Query: 10 GSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69
G+ PP P L ++P P SST + S+S ++ L+ L +M
Sbjct: 4192 GTQTGPPTHTSTAPIAELTTSNPPP--ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 4249
Query: 70 KQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLH 129
PP P P GG+ + PPP S
Sbjct: 4250 TA-----------PPSTPTAPTTTSGGH--------TLSPPPSTTTS------------- 4277
Query: 130 HQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQP--PPSYYPPTSSQPYLPPA 187
PPG + S P P + ++ P P P PS T +PY
Sbjct: 4278 -----PPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPY---- 4328
Query: 188 QPSPSQ----SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243
PS + +Y AP + + Y + + S PS
Sbjct: 4329 ---PSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPST------ 4379
Query: 244 LLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWY 298
P P+ P T +P + +K + P+ DP P+++ + W+
Sbjct: 4380 ----PSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDP----PRQENETWW 4426
Score = 35.4 bits (80), Expect = 0.61
Identities = 35/172 (20%), Positives = 52/172 (30%), Gaps = 44/172 (25%)
Query: 1481 SEPQMADHLPPQESRLQNTSSRPGMYP-----PPGSYRPPPPMGKPPGSIVRPSAPPARS 1535
S P PP + ++ P P PP + P PP P + + P +
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPT 1678
Query: 1536 SVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEF 1595
+ P + P+ P PP + P P P +
Sbjct: 1679 TTPSS--PITTTPSPPTTTMTTPSPTTTPSSPIT-------------------------- 1710
Query: 1596 KSETAAIPSAPVLP-PPPVHSSIPPPGPVP-------MGMPPMSKPPPVQQT 1639
T PS+ P PPP + P P P +PP + P+ T
Sbjct: 1711 ---TTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTT 1759
Score = 35.4 bits (80), Expect = 0.61
Identities = 39/187 (20%), Positives = 58/187 (31%), Gaps = 57/187 (30%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
PP P PPP P +TTP+ P+++
Sbjct: 1636 PPTTTPSPPPTTTTTPPP------TTTPSPPTTT-------------------------- 1663
Query: 75 VLQPHHLPPPPL-----PPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLH 129
P PP+ PPP P PP P P +
Sbjct: 1664 ------TPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSS 1717
Query: 130 HQRDGPPGLVPMELESP-PESPPVPPGSYM----------PPSQSYMPPPQPPPSYYPPT 178
PP P + +P P + P PP + M P + + +PP PP++ P +
Sbjct: 1718 TTTPSPP---PTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFS 1774
Query: 179 SSQPYLP 185
++ P P
Sbjct: 1775 TTTPTTP 1781
Score = 35.4 bits (80), Expect = 0.61
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 1507 PPPGSYRPPPPMGKP-PGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQ 1565
PPP + P P P P + + PP +S P+T P+ PP PP P P
Sbjct: 1723 PPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL---PPSITPPTFSPFSTTTPT 1779
Query: 1566 TSAVEQERW 1574
T V W
Sbjct: 1780 TPCVPLCNW 1788
Score = 34.3 bits (77), Expect = 1.4
Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 20/168 (11%)
Query: 1484 QMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPP 1543
+M PP T+S PP S PP G+ S+ P S+V T
Sbjct: 4246 EMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTS 4305
Query: 1544 VPIPPPPPPPPLPPPPPV----IKPQTSAVEQERWDEDSFYGLWDT--NDEQG------- 1590
P P PL P + ++P S+V D++Y + N G
Sbjct: 4306 A---WTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVN 4362
Query: 1591 --LNSEFKSETAAIPSAPVLPPPPVHSSIPP--PGPVPMGMPPMSKPP 1634
L+ + + PS P P P S+ P P P P +KPP
Sbjct: 4363 CSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 4410
Score = 33.5 bits (75), Expect = 2.3
Identities = 31/126 (24%), Positives = 37/126 (29%), Gaps = 13/126 (10%)
Query: 1517 PMGKPPGSIVRPSAPPARSSVPVTRP---PVPIPPPPPPPPLPPPPPVIKPQTSAVEQER 1573
PM K I PS P S P T P P PP PPP P
Sbjct: 1391 PMDK---CITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447
Query: 1574 WDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKP 1633
T +++ PS P P P ++ PP PP + P
Sbjct: 1448 PPP-------TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTP 1500
Query: 1634 PPVQQT 1639
P T
Sbjct: 1501 SPPTTT 1506
Score = 32.0 bits (71), Expect = 6.7
Identities = 35/140 (25%), Positives = 43/140 (30%), Gaps = 28/140 (20%)
Query: 1522 PGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP------PLP------PPPPVIKPQTSAV 1569
P P+ P ++ VT P P PP P+ PPP PQTS
Sbjct: 4167 PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRS 4226
Query: 1570 EQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLP---------PPPVHSSIPPP 1620
E T L + + A PS P P PP ++ PP
Sbjct: 4227 TSSPLTE-------STTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPP 4279
Query: 1621 GPVPMGMPPMSKPPPVQQTV 1640
G G S P TV
Sbjct: 4280 GTPTRGTTTGSSSAPTPSTV 4299
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 97.4 bits (241), Expect = 1e-19
Identities = 103/370 (27%), Positives = 132/370 (35%), Gaps = 69/370 (18%)
Query: 522 PYSQMPPPLPTMPPPV---LPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGM 578
P S +P PLP PP+ P ++PPP +PP P + PP P P +PPPG
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTP--PLGIPPPGF 711
Query: 579 PPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGV 638
P + PPP PPP L P LPP L PPP+ TPP IPPP
Sbjct: 712 GPGV----PPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI---------TPPVSIPPPHT 758
Query: 639 PQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPL---QSAGPS 695
P P L + A S S ++ P PT + PP T L Q P
Sbjct: 759 PPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLP---TPPVTQPVSLLGTQGVAPG 815
Query: 696 EQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLE 755
+ +AP + + GL P P ++ P+ P PP +
Sbjct: 816 PVIGLQAPST------GLLGARPGLIPLQRPPGMPPPHLQRFPLMPPR--PMPPHMMHRG 867
Query: 756 SPRGPR-FDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPR 814
P GP F P +GP P P GP R G P G
Sbjct: 868 PPPGPGGFAMPPPHG-----MKGPFP---------PHGPFVRPGGMPGLG---------- 903
Query: 815 GPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQ 874
GP P GP+ + + QQ QQQP+ QA ++ S Q
Sbjct: 904 GPG------------PGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQP 951
Query: 875 KNFKMQSAAF 884
+ Q F
Sbjct: 952 PPTQQQPQQF 961
Score = 81.6 bits (200), Expect = 7e-15
Identities = 91/341 (26%), Positives = 121/341 (35%), Gaps = 79/341 (23%)
Query: 514 MSMPPPFVPYSQMPPPLP------------TMPPPVLPPSLPPPVMPPA----------L 551
+++PPP VP Q PP+ +PPP P +PPP PP L
Sbjct: 675 ITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHL 734
Query: 552 PATVPPPGMPPPVMPPSLPTSVPPPGMPP------------------SLSSAGPPPVLPP 593
P PPG PPP+ P P S+PPP PP S+ G +PP
Sbjct: 735 PPGFLPPGPPPPITP---PVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYG--SAVPP 789
Query: 594 PSLSSAGPPPVLPPPSLSST---APPPVMPL-----------PPLSSATPPPGIPPPGV- 638
+ ++ PPV P SL T AP PV+ L P L PPG+PPP +
Sbjct: 790 AAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQ 849
Query: 639 ------PQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLP-TPVSFGSAPPTTYHPPLQS 691
P+ +PP + PP + P + P P P P
Sbjct: 850 RFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGP 909
Query: 692 AGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRS 751
GP ++ + P P Q AP QP + P S P +
Sbjct: 910 GGPEDRDGRQQP------PQQPQQQPQ-----PQAPQQPQQQQQQQPPPSQQPPPTQQQP 958
Query: 752 SYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFE-GNRPD 791
+ +F+ R E G R G R + R GNR D
Sbjct: 959 QQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRERYGNRND 999
Score = 63.5 bits (153), Expect = 2e-09
Identities = 92/369 (24%), Positives = 125/369 (33%), Gaps = 76/369 (20%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
P P+P P PV +P P P + P P HQ
Sbjct: 654 PVSPIPKPLPVPVPPI-PVPAPITVPPPQVPP---------------------HQPGPPV 691
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134
V L PP PP +P G+G PPPPP PP L
Sbjct: 692 V---GALQPPAFTPPLGIPPPGFGPGVPPPPPPPP-----------------FLR----- 726
Query: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYP-----PTSSQPYLPPAQP 189
PG PM L P PP PP PP +PPP PP P + +
Sbjct: 727 -PGFNPMHL-PPGFLPPGPPPPITPPVS--IPPPHTPPISIPNLVSGARGNAESGDSVKM 782
Query: 190 SPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPP- 248
S PP+ PTP + S L +Q P PS G ++ P
Sbjct: 783 YGSAVPPAAPTNLPTPPVTQPVS-----LLGTQGVAPGPVIGLQAPSTGLLGARPGLIPL 837
Query: 249 --PPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPS--TMTPQEQQQYWYRQHLLS 304
PP PP + +Q+ PL + P P P M P + + H
Sbjct: 838 QRPPGMPPPH---LQRFPL-MPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPF 893
Query: 305 LQQRTKVHLPGHKKGPVVAKD---TPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVP 361
++ L G GP +D +P ++ P Q P+ P ++ PPP+++ P
Sbjct: 894 VRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQP-QPQAPQQPQQQQQQQPPPSQQPP 952
Query: 362 PPLPPEEPQ 370
P ++PQ
Sbjct: 953 P--TQQQPQ 959
Score = 56.2 bits (134), Expect = 3e-07
Identities = 95/392 (24%), Positives = 134/392 (34%), Gaps = 118/392 (30%)
Query: 1483 PQMADHLP--PQESRLQNTSSRP--GMYPP---PGSYRPPPP----------MGKPPGSI 1525
PQ+ H P P LQ + P G+ PP PG PPPP M PPG +
Sbjct: 680 PQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFL 739
Query: 1526 VRPSAPPARSSVPVTRPPVPIPP---------------------------PPPPPPLPPP 1558
P PP + PV+ PP PP PP P P
Sbjct: 740 --PPGPPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPT 797
Query: 1559 PPVIKPQTSAVEQ-------------ERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSA 1605
PPV +P + Q + GL G+ +P
Sbjct: 798 PPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPR 857
Query: 1606 PVLPPPPVHSSIPPPGPV----------------------PMGMPPMSKPPPVQQTVDYG 1643
P +PP +H PPPGP P GMP + P P +
Sbjct: 858 P-MPPHMMHRG-PPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDR 915
Query: 1644 HGRDISTNKVEQIPYGE-----RITLRPDPLPERSTFETEHAGQRDRYDR---------- 1688
GR + +Q P + + + P P + T+ Q+ R D
Sbjct: 916 DGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQ 975
Query: 1689 ------------ERDREPYFDR---QSNVIADHRDFKR---DRETHRD-RDRDRGVIDY- 1728
E DRE Y +R + N D R++ R DR+ HRD +R+R +
Sbjct: 976 ERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHR 1035
Query: 1729 DRDRFDRERRPRDDRAQSYRDKKDHSSSRRGG 1760
DR+R R+R R ++ ++ +K + R GG
Sbjct: 1036 DRERDSRDRESRREKEEARGKEKPEVTDRAGG 1067
Score = 52.0 bits (123), Expect = 6e-06
Identities = 63/226 (27%), Positives = 82/226 (36%), Gaps = 50/226 (22%)
Query: 15 PPPPVPPP--------PPVALPEASPGPG-----------YSSSTTPAAPSSSGFMSFRE 55
PPPP+ PP PP+++P G Y S+ PAAP++ +
Sbjct: 743 PPPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQ 802
Query: 56 -------QHLAQLQQLQQMHQKQMQCVLQPHHLP---PPPLPPP-----PVMPGGGYGDW 100
Q +A + +P +P PP +PPP P+MP
Sbjct: 803 PVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPP------ 856
Query: 101 QPPPPPMP---PPPGPA-LSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPP-- 154
+P PP M PPPGP + K H PG +P L P P P
Sbjct: 857 RPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMP-GLGGPGPGPGGPEDR 915
Query: 155 -GSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQ-PSPSQSPPSQ 198
G PP Q P QP P Q PP+Q P P+Q P Q
Sbjct: 916 DGRQQPPQQPQQQP-QPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQ 960
Score = 49.3 bits (116), Expect = 4e-05
Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 1/131 (0%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75
P PP P A A+ P +S P AP ++ Q Q + Q + M
Sbjct: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQ 349
Query: 76 LQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135
P H PLPP MPG G P PP P P Q+ Q Q +
Sbjct: 350 QDPMH-HQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 408
Query: 136 PGLVPMELESP 146
P ME+E P
Sbjct: 409 PHQQEMEVEQP 419
Score = 47.0 bits (110), Expect = 2e-04
Identities = 76/299 (25%), Positives = 104/299 (34%), Gaps = 54/299 (18%)
Query: 329 PVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAA 388
PV E VT S P S EPP + P P PQ P DA AA A
Sbjct: 143 PVAENVTNNEGSPPPPVKVSSEPP-----TQATPNSVPAVPQL--PSSDA-----FAAVA 190
Query: 389 HWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQF 448
Q Q + QLQQILQ +QQ PP Q+ ++D + Q
Sbjct: 191 QLFQTTQGQ-------------QLQQILQTFQQ----PPKPQSPALDNAV------MAQV 227
Query: 449 QHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWK---TWQGHMKATQSYLQEKVNSFQN 505
Q + + + EQ ++P +Q ++K+ + +A + +E +
Sbjct: 228 QAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAV-- 285
Query: 506 MKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVM 565
+ P VP P P T+P P + PP PP P P GM P
Sbjct: 286 -------TTTAPAAAVP----PAPTATVPAAAAPAAASPP--PPQAPFGFPGDGMQQPAY 332
Query: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPL 624
P M V PP+ G +LP P A P + P PP+
Sbjct: 333 TQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPG-FGLLPTPPFPPMAQPVIPPTPPV 390
Score = 47.0 bits (110), Expect = 2e-04
Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 58/172 (33%)
Query: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP-PGSIVRPSAPPARSS 1536
D+ P+ ++ Q + + + P P P PP+ P P ++ P PP +
Sbjct: 629 DWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPG 688
Query: 1537 VPVT--------RPPVPIPPPP-----PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
PV PP+ IPPP PPP PPPPP ++P
Sbjct: 689 PPVVGALQPPAFTPPLGIPPPGFGPGVPPP--PPPPPFLRP------------------- 727
Query: 1584 DTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
G N P+ PP PPGP P PP+S PPP
Sbjct: 728 ------GFN-------------PMHLPP----GFLPPGPPPPITPPVSIPPP 756
Score = 43.9 bits (102), Expect = 0.002
Identities = 65/286 (22%), Positives = 92/286 (32%), Gaps = 44/286 (15%)
Query: 15 PPPPVP---PPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71
PPPPV PP A P + P P PSS F + +AQL Q Q +Q
Sbjct: 155 PPPPVKVSSEPPTQATPNSVPA-------VPQLPSSDAFAA-----VAQLFQTTQ--GQQ 200
Query: 72 MQCVLQPHHLPPPPLPPPPVMPGGGYGDWQ------PPPPPMP-------PPPGPALSYQ 118
+Q +LQ PP P P + Q P P PPP ++
Sbjct: 201 LQQILQTFQ--QPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFD 258
Query: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178
K+ + D P + + E P + +PP+ + P P+ P
Sbjct: 259 KKLLDRFD----YDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASP- 313
Query: 179 SSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS----- 233
P P P P+ + + Q H Q LP + P
Sbjct: 314 -PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLP 372
Query: 234 RPSQGHSKSQLLAPPPPSAPPGNKT-TVQQEPLESGAKNKSTEQQQ 278
P ++ P PP P + Q EPL + E +Q
Sbjct: 373 TPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQ 418
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/301 (20%), Positives = 104/301 (34%), Gaps = 89/301 (29%)
Query: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT--------------------P 205
PPP S PPT + P PA P Q P S ++ A P
Sbjct: 155 PPPPVKVSSEPPTQATPNSVPAVP---QLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211
Query: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQ--- 262
S + + ++ Q+ + +P++PS+ + PPP +K + +
Sbjct: 212 PKPQSPALDNAVMAQVQAITAQLKTTPTQPSE----QKAAFPPPEQKTAFDKKLLDRFDY 267
Query: 263 ----EPLESGAKNKSTEQQQAAPE----PDPSTMTP-----------------------Q 291
E +E K +T AP P P+ P
Sbjct: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327
Query: 292 EQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP 351
+Q Y Q++ Q R + G ++ +P+ +V +P Q+P P
Sbjct: 328 QQPAYTQHQNMDQFQPR----MMGIQQ---------DPMHHQVPLPPNGQMPGFGLLPTP 374
Query: 352 PLPPPNEEVPPPLPP------------EEPQSEDP-EEDARLKQ--LQAAAAHWQQHQQH 396
P PP + V PP PP EP ++ P +++ ++Q +Q H +++
Sbjct: 375 PFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKS 434
Query: 397 R 397
R
Sbjct: 435 R 435
Score = 43.1 bits (100), Expect = 0.003
Identities = 38/164 (23%), Positives = 59/164 (35%), Gaps = 14/164 (8%)
Query: 82 PPPPLPPPPV--MPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLV 139
P +PP P +P PPPP P P Q+ +HQ + + P ++
Sbjct: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQ---PRMM 346
Query: 140 PMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQS 199
++ + P+PP MP PP PP +QP +PP P Q P S
Sbjct: 347 GIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPP-------MAQPVIPPT--PPVQQPFQAS 397
Query: 200 YLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243
+ A + + + S +R S+ S S+
Sbjct: 398 FQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR 441
Score = 42.0 bits (97), Expect = 0.006
Identities = 53/226 (23%), Positives = 82/226 (36%), Gaps = 39/226 (17%)
Query: 1529 SAPPA-RSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTND 1587
+ PPA ++VP P PPPP P P ++ Q + + + D+
Sbjct: 293 AVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQ-QPAYTQHQNMDQ----------- 340
Query: 1588 EQGLNSEFKSETAAIPSAPV-----LPPP---PVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639
F+ I P+ LPP P +P P PM P + PPVQQ
Sbjct: 341 -------FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQ- 392
Query: 1640 VDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRY-----DRERDREP 1694
+ + Q P+ + + + + E +++ R R R R R
Sbjct: 393 -PFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSG 451
Query: 1695 YFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740
R+S R R R+ R R R DR++ +RERR +
Sbjct: 452 SRSRRSR---HRRSRSRSRDRRRHSPRSRSQERRDREK-ERERRQK 493
Score = 37.4 bits (85), Expect = 0.16
Identities = 74/350 (21%), Positives = 113/350 (32%), Gaps = 81/350 (23%)
Query: 1497 QNTSSRPGMYPPPGSYRPPPPMGKPPGSIVR-PSAPPARSSVPVTR-------------- 1541
+N ++ G PPP PP P S+ P P + + V +
Sbjct: 146 ENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQIL 205
Query: 1542 PPVPIPPPPPPPPL------------------PPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
PP P P L P P K EQ+ + +
Sbjct: 206 QTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRF 265
Query: 1584 DTNDEQGLNSEFKSE--TAAIPSAPVLPPPPVHSSI-----------PPPGPVPMGMP-- 1628
D +DE E K E TA +AP PP ++ PPP P G P
Sbjct: 266 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGD 325
Query: 1629 PMSKPPPVQ-QTVDYGHGRDISTNKVEQIPYGERITLRPD---------------PL--- 1669
M +P Q Q +D R + ++Q P ++ L P+ P+
Sbjct: 326 GMQQPAYTQHQNMDQFQPRMMG---IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQP 382
Query: 1670 ------PERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDR 1723
P + F+ Q + ++ + + + I + + D R R R
Sbjct: 383 VIPPTPPVQQPFQASFQAQNEPL-TQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR 441
Query: 1724 GVIDYDRDRFDRERRPRDDRAQS-YRDKKDHSSSRRGGFDRPSYDRKSDR 1772
R RR R R++S RD++ HS R R DR+ +R
Sbjct: 442 SPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERR---DREKER 488
Score = 35.8 bits (81), Expect = 0.46
Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 29/209 (13%)
Query: 1171 PEPGDGGEKMYPYHRDE---PPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYW 1227
P PG GG M P H + PP P+ P G P +R+ R++
Sbjct: 868 PPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRD-----GRQQPP 922
Query: 1228 RECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMD 1287
++ ++ Q + ++ + PPS+ ++ P Q D NR+ + +
Sbjct: 923 QQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP--------QQFRND-NRQ-QFNSG 972
Query: 1288 RDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYR 1347
RD +R R + ++N+ +R YG D++++ R+R P DR+R
Sbjct: 973 RDQERFGR--RSFGNRVENDRER-YGNRNDDRDNSNRDRREWGRRS-------PDRDRHR 1022
Query: 1348 DDRWREERNREH-GYDRDFRDRGELRIRE 1375
D R R+ H +RD RDR R +E
Sbjct: 1023 DLEERNRRSSGHRDRERDSRDRESRREKE 1051
Score = 33.9 bits (76), Expect = 1.8
Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 46/201 (22%)
Query: 1134 IPPRRAGSR--ERGPPRGPGSRERGLGRSDFGRDRGPFRPE---------PGDGGEKMYP 1182
+PPR RGPP GPG G +GPF P PG GG P
Sbjct: 854 MPPRPMPPHMMHRGPPPGPG----GFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGP 909
Query: 1183 ------YHRDEPPRAPWNHGE-------ERGHEEFPLDGRNAPMERERLDDW-------- 1221
R +PP+ P + ++ ++ P + P +++ +
Sbjct: 910 GGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQF 969
Query: 1222 ----DRERYWRECERDYQDDTLELY-NREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDE 1276
D+ER+ R + ++ E Y NR D + RR P D +R +D++E
Sbjct: 970 NSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSP---DRDRHRDLEE 1026
Query: 1277 DYNREM-ERDMDRDV-DRISR 1295
R RD +RD DR SR
Sbjct: 1027 RNRRSSGHRDRERDSRDRESR 1047
Score = 33.5 bits (75), Expect = 2.3
Identities = 31/130 (23%), Positives = 47/130 (36%), Gaps = 45/130 (34%)
Query: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPP-----------PGSYRPPPPM---GKPPG 1523
D+ EP+ + +++ T++ PP P + PPPP G P
Sbjct: 266 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGD 325
Query: 1524 SIVRPS------------------APPARSSVPVTRPP---------VPIPPPPP--PPP 1554
+ +P+ P VP+ PP +P PP PP P
Sbjct: 326 GMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPL--PPNGQMPGFGLLPTPPFPPMAQPV 383
Query: 1555 LPPPPPVIKP 1564
+PP PPV +P
Sbjct: 384 IPPTPPVQQP 393
Score = 32.7 bits (73), Expect = 3.9
Identities = 28/90 (31%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPP----VMPP 567
G +MPPP M P P P V P + P L P PG P PP
Sbjct: 873 GGFAMPPP----HGMKGPFPPHGPFVRPGGM------PGLGGPGPGPGGPEDRDGRQQPP 922
Query: 568 SLPTSVP---PPGMPPSLSSAGPPPVLPPP 594
P P P P PPP PP
Sbjct: 923 QQPQQQPQPQAPQQPQQQQQQQPPPSQQPP 952
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 96.7 bits (239), Expect = 2e-19
Identities = 165/695 (23%), Positives = 224/695 (32%), Gaps = 126/695 (18%)
Query: 9 GGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68
G + Y PPP+ PP P P+++P +S + + +G+ + E +++ Q
Sbjct: 154 GPARPYHPPPLFPPSPQP-PDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQA---- 208
Query: 69 QKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQML 128
PP PP P + GG G PP P G A S
Sbjct: 209 -------------PPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSV----------- 244
Query: 129 HHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQ 188
GP G PP P S S PP +PP + P P+
Sbjct: 245 ----GGPNG-------GKQHPPPTTPISVSSSGASGAPPTKPPTT---PVGGGNL--PSA 288
Query: 189 PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS-------K 241
P P+ P L P P+ +++S S LP SP QG K
Sbjct: 289 PPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
Query: 242 SQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQH 301
LAP P S PP + ++ P+ + S+ A+ S+ +
Sbjct: 349 GPTLAPSPHSLPPAS-SSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP--------- 398
Query: 302 LLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVT-VPATSQVPESPS----SEEPPLPPP 356
P + P P P V+ P P PS S+ PP PPP
Sbjct: 399 -----------FPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
Query: 357 NEEV-------PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKH 409
+ P P PP A+ + H HQQ Q Q Q+
Sbjct: 448 YGRLLANSNAHPGPFPPST--------GAQSTAHPPVSTHHHHHQQ-----QQQQQQQQQ 494
Query: 410 TQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSY 469
Q QQ Q + PPP ++ H+ L R + H
Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL--RPYP--PGPAHLP 550
Query: 470 PHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPP 529
P Q+ Y + ++ S S+ + S P PY P P
Sbjct: 551 PPHSQVS-YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP----SPSQGPQGAPYPFPPVP 605
Query: 530 LPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP----PVMPPSLPTSVPP---PGMPPSL 582
T L + PA T PPG PP P + T+ PP PG PPS
Sbjct: 606 TVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSF 665
Query: 583 SSAGPPPV--LPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQ 640
+ PP PP AGP P S T P PLPP + P PPP P
Sbjct: 666 RTGTPPGYRGTSPP----AGPGTFKPG---SPTVGPG--PLPPAGPSGLPSLPPPPAAPA 716
Query: 641 GIPP-QLTAAPVPPASSSQSSQVPEKPRPALLPTP 674
PP T PA ++ + P P + P P
Sbjct: 717 SGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Score = 91.7 bits (226), Expect = 7e-18
Identities = 102/380 (26%), Positives = 133/380 (35%), Gaps = 67/380 (17%)
Query: 528 PPLPTMPPPVLPPSLPPPVMPPALP-------ATVPPPGMPPPVMPPSLPTSVPPPGMP- 579
P P PPP+ PPS PP P P +V P G P+ PP+ PPG P
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 580 --PSLSSAGPPPVLPPPSLSSAG----------------PPPVLP---PPSLSSTAPPPV 618
P L G VL P + G PPP P S +S APP
Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274
Query: 619 MPLPPLSSATPPPGIPP---PGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPV 675
P P+ P PP P V +PP P+ AS+S + +P P LP+P
Sbjct: 275 PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG-LGAQPLPGHLPSPH 333
Query: 676 SFGSA----PPTTYHPPLQSAGPSE--QVNSKAPLSKSALPYSSFSSDQGLGESSAAPS- 728
+ G PP P + P +S AP PYSS SS SS++ S
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS 393
Query: 729 ---QPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRF 785
P A + +P PP +S S + P++ P +GP P P
Sbjct: 394 SSASPFPASQALPSYPHSF---PPPTSLSVSNQPPKYTQP-SLPSQAVWSQGPPPPPP-- 447
Query: 786 EGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFG 845
G + + G P +Q P S Q +
Sbjct: 448 ------------YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ------Q 489
Query: 846 QQHQQQPKSQAEPLSGNKEP 865
QQ QQQ + Q + GN P
Sbjct: 490 QQQQQQQQQQQQQHHGNSGP 509
Score = 74.7 bits (182), Expect = 9e-13
Identities = 105/374 (28%), Positives = 135/374 (36%), Gaps = 61/374 (16%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLP------PPVMPPALPATVPPPGMPPPVM 565
G PPP P S + + PP PP+ P P PPA V P PPP +
Sbjct: 249 GGKQHPPPTTPIS-VSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPAL 307
Query: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLS 625
P S PPG L + P LP P G + P P T P LPP S
Sbjct: 308 RPLNNASASPPG----LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPAS 363
Query: 626 SATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTY 685
S+ P PP P +AA +SSS SS P AL P SF PPT+
Sbjct: 364 SSAP---APPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF--PPPTSL 418
Query: 686 ----HPP--LQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPV 739
PP Q + PS+ V S+ P PY L S+A P
Sbjct: 419 SVSNQPPKYTQPSLPSQAVWSQGP--PPPPPYGRL-----LANSNAHP------------ 459
Query: 740 RSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEG 799
G P S P ++ + + + + + + GN P P
Sbjct: 460 --GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN-SGPPPPGAFP 516
Query: 800 HPAEGTKSKWGMIPRGPASQFYITPST-SLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEP 858
HP EG S A + ++PS SL P GP P H Q SQA P
Sbjct: 517 HPLEGGSSH-------HAHPYAMSPSLGSLRPYPPGPAHLPP------PHSQVSYSQAGP 563
Query: 859 LSGNKEPLADTSSN 872
N P++ +S++
Sbjct: 564 ---NGPPVSSSSNS 574
Score = 73.6 bits (179), Expect = 2e-12
Identities = 90/326 (27%), Positives = 117/326 (35%), Gaps = 59/326 (18%)
Query: 12 SHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71
S PPPP P +A A PGP + ST + + + H Q QQ QQ Q+Q
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGP-FPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497
Query: 72 MQCVLQPHH---LPPPPLPPPPVMPGGGYGDWQP--PPPPM----PPPPGPALSYQKQQQ 122
Q Q HH PPPP P + GG P P + P PPGPA
Sbjct: 498 QQ--QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA-----HLP 550
Query: 123 YKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPP----T 178
H + + + GP G P S S GSY S PQ P +PP T
Sbjct: 551 PPHSQVSYSQAGPNG--PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVT 608
Query: 179 SSQPYLPPAQPSPSQSPPSQSYLAP--TPSYSSSSSSSQSYLSHS-QSYLPSSQAS---- 231
+S L + + SP +P P Y + S +Y + + Y P S S
Sbjct: 609 TSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTG 668
Query: 232 ------------------PSRPS--------QGHSKSQLLAPP---PPSAPPGNKTTVQQ 262
P P+ G S L PP P S PP + T ++Q
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728
Query: 263 EPLESGAKNKSTEQQQAAPEPDPSTM 288
EP E +S +P P P +
Sbjct: 729 EPAEEYETPESPVPPARSPSPPPKVV 754
Score = 72.4 bits (176), Expect = 4e-12
Identities = 165/693 (23%), Positives = 218/693 (31%), Gaps = 148/693 (21%)
Query: 103 PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ 162
PPP PP P P S +Q + + P + P +P E PP S M +
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEP-------HPSVTPTGYHAPME----PPTSRMFQAP 209
Query: 163 SYMPPPQPPPSYYPP-TSSQPYLPPAQP-----SPSQSPPSQSYLAPTPSYSSSSSSSQS 216
PPP P YP T PP P + S P+ P P+ S SSS +
Sbjct: 210 PGAPPPHP--QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267
Query: 217 YLSHSQSYLPSSQASPSRP-SQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTE 275
S A P++P + L + PPP+ P + P N S
Sbjct: 268 -----------SGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASAS 316
Query: 276 QQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPG-HKKGPVVAKDTPEPVKEEV 334
+P P HLP H G + P P K
Sbjct: 317 PPGLGAQPLPG-------------------------HLPSPHAMGQGMGGLPPGPEKGPT 351
Query: 335 TVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQ 394
P SP S LPP + P P P P S A AA++
Sbjct: 352 LAP-------SPHS----LPPASSSAPAP-PMRFPYSSSSSSSA------AASSSSSSSS 393
Query: 395 QHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQE 454
F Q L Y PP ++SV Q Y Q ++ +
Sbjct: 394 SSASPFP----------ASQALPSYPHSFPPPT---SLSVSNQPPKYTQPSLPSQAVWSQ 440
Query: 455 -------WEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMK 507
+ R +P Q + H Q Q++ Q +
Sbjct: 441 GPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQ 500
Query: 508 NQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVP-PPGMPPPVMP 566
Q+ GN PPP P PL P M P+L + P PPG
Sbjct: 501 QQHHGNSGPPPP----GAFPHPLEGGSSH----HAHPYAMSPSLGSLRPYPPG------- 545
Query: 567 PSLPTSVPPPGMPPSLSSAGP--PPVLPPPSLSSAGP----PPVLPPPSLSST-APPPVM 619
P +PPP S S AGP PPV + SS+ P P PS AP P
Sbjct: 546 ---PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFP 602
Query: 620 PLPPLSS------------ATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPR 667
P+P +++ A+ P G P G PP AP P A + + P +
Sbjct: 603 PVPTVTTSSATLSTVIATVASSPAGYKTAS-PPGPPPYGKRAPSPGAYKTAT---PPGYK 658
Query: 668 PALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAP 727
P +P SF + P Y AGP + LP + S L AAP
Sbjct: 659 PG---SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAP 715
Query: 728 SQPITAVKDMPVRSGGLLPDPPRSSYLESPRGP 760
+ P S + P Y E+P P
Sbjct: 716 ASG-------PPLSATQIKQEPAEEY-ETPESP 740
Score = 68.6 bits (166), Expect = 6e-11
Identities = 112/454 (24%), Positives = 158/454 (34%), Gaps = 109/454 (24%)
Query: 9 GGSSHY----------------PPPPVPPPPP---VALPEASP-GPGYSSSTTPAAPSSS 48
GGSSH+ PP P PPP V+ +A P GP SSS+ ++ +S
Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
Query: 49 GFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVM---------------- 92
G S+ H + Q Q P P PP P +
Sbjct: 581 G--SYPCSHPSPSQGPQG---------------APYPFPPVPTVTTSSATLSTVIATVAS 623
Query: 93 PGGGYGDWQPPPPP----MPPPPGPALSYQKQQQYKHQMLHHQRDG-PPGLVPMELESPP 147
GY PP PP P PG A YK R G PPG
Sbjct: 624 SPAGYKTASPPGPPPYGKRAPSPG-AYKTATPPGYKPGSPPSFRTGTPPGY-------RG 675
Query: 148 ESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPP-SQSYLAPTPS 206
SPP PG++ P S + P P PP S P LPP +P+ PP S + + P+
Sbjct: 676 TSPPAGPGTFKPGSPTVGPGPLPPAG----PSGLPSLPPPPAAPASGPPLSATQIKQEPA 731
Query: 207 YSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGH-------------SKSQLLAPPPPSAP 253
+ S + S S P PS SQ ++S L P +
Sbjct: 732 EEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSK 791
Query: 254 PGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHL 313
K E + A+ ++ E+++ E + +E+++ R L+ + R V
Sbjct: 792 LAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVEC 851
Query: 314 PGHKKGPVVAKDTPEPVKEEVTV--------PATSQVPE-------SPSSEEPPLPPPNE 358
P GPV + EP TV PA + E SP + P P
Sbjct: 852 P--SLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLG 909
Query: 359 EVP--------PPLPPEEPQSEDPEEDARLKQLQ 384
V P L +P + + E +AR + L+
Sbjct: 910 AVDPGLLGYNVPALYSSDPAAREREREARERDLR 943
Score = 64.3 bits (155), Expect = 1e-09
Identities = 100/396 (25%), Positives = 145/396 (36%), Gaps = 106/396 (26%)
Query: 1499 TSSRPG------MYPPPGSYRPPPPMGKPPGS--IVRPSAPPA-RSSVPVTRP------- 1542
T+S PG P PG+Y+ P G PGS R PP R + P P
Sbjct: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS 689
Query: 1543 ----PVPIPPPPPP--PPLPPPP--PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSE 1594
P P+PP P P LPPPP P P SA ++
Sbjct: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSA------------------------TQ 725
Query: 1595 FKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVE 1654
K E A P P PP S PPP V + P Q+ + D N
Sbjct: 726 IKQEPAEEYETPESPVPPARSPSPPPKVVDV-------PSHASQSARFNKHLDRGFNSCA 778
Query: 1655 Q-----IPY-GERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRD 1708
+ +P G ++ + L E+ E E QR R ++ER+RE R+
Sbjct: 779 RSDLYFVPLEGSKLAKKRADLVEKVRREAE---QRAREEKERERE-------------RE 822
Query: 1709 FKRDRETHRDRDRDRGVIDYDRDRFDRE--------RRPRDDRAQSYRDKKDHSSSRRGG 1760
+++RE ++R+ +R V R E RP + + + G
Sbjct: 823 REKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYL-----G 877
Query: 1761 FDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPA----------PSLSHQPPPAPRV 1810
D P+ S+ Y P + R +P +PL A P+L P A
Sbjct: 878 PDTPALRTLSE---YARPHVMSPGNRNHP-FYVPLGAVDPGLLGYNVPALYSSDPAARER 933
Query: 1811 EKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSG 1846
E++ +++ D LK PG E +P + + G+PG G
Sbjct: 934 EREARERDLRDRLK-PGFEVKPSELEP-LHGVPGPG 967
Score = 60.8 bits (146), Expect = 1e-08
Identities = 44/125 (35%), Positives = 52/125 (41%), Gaps = 15/125 (12%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVM---PPALPATVPPPGMPPPVMPPSLPTSV 573
PPP+ + P T PP P PP PP T PP G P P PT
Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG--PGTFKPGSPTVG 693
Query: 574 PPPGMPPSLSSAGPP--PVLPPPSLSSAGPPPVLPPPSLSSTA---PPPVMPLPPLSSAT 628
P P +PP AGP P LPPP + A PP+ A P P+PP S +
Sbjct: 694 PGP-LPP----AGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPS 748
Query: 629 PPPGI 633
PPP +
Sbjct: 749 PPPKV 753
Score = 45.8 bits (107), Expect = 4e-04
Identities = 33/84 (39%), Positives = 40/84 (47%), Gaps = 6/84 (7%)
Query: 517 PPPFVPYSQM--PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVP 574
P F P S P PLP P LP SLPPP PA PA+ PP P+ P
Sbjct: 682 PGTFKPGSPTVGPGPLPPAGPSGLP-SLPPP---PAAPASGPPLSATQIKQEPAEEYETP 737
Query: 575 PPGMPPSLSSAGPPPVLPPPSLSS 598
+PP+ S + PP V+ PS +S
Sbjct: 738 ESPVPPARSPSPPPKVVDVPSHAS 761
Score = 44.3 bits (103), Expect = 0.001
Identities = 56/233 (24%), Positives = 86/233 (36%), Gaps = 52/233 (22%)
Query: 1483 PQMADHLPPQESR--LQNTSSRP---GMYPPPGSYRPPPPMGK-----PPGSIVRPSAPP 1532
P + +LPP + L N S+ P G P PG P MG+ PPG P+ P
Sbjct: 295 PHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP 354
Query: 1533 ARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLN 1592
+ S+ PP P PP+ P +S+ S ++
Sbjct: 355 SPHSL------------PPASSSAPAPPMRFPYSSSSSSSAAASSS------SSSSSSSA 396
Query: 1593 SEFKSETAAIPSAPVLPPPPVHSSI---PPPGPVP---------MGMPPMSKPPPVQQTV 1640
S F + + A+PS P PPP S+ PP P G PP PPP
Sbjct: 397 SPFPA-SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP---PPP----- 447
Query: 1641 DYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDRE 1693
+GR ++ + P+ + P ST H Q+ + +++ ++
Sbjct: 448 ---YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497
Score = 43.9 bits (102), Expect = 0.002
Identities = 78/343 (22%), Positives = 118/343 (34%), Gaps = 45/343 (13%)
Query: 636 PGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTY---------- 685
P P PP +P PP S+ + + +P P++ PT PPT+
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 686 -HPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGL 744
HP L G ++ K SS G G+ P+ PI+ + G
Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG-GKQHPPPTTPISVSSS---GASGA 270
Query: 745 LPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEG 804
P P ++ + P P F + P P R N P P G
Sbjct: 271 PPTKPPTTPVGGGNLPSAPPPANFPHVTPNL--PPPPALRPLNNASASP-------PGLG 321
Query: 805 TKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKE 864
+ G +P A + GP+ KGP A H P S + P +
Sbjct: 322 AQPLPGHLPSPHAM------GQGMGGLPPGPE-KGPTLA-PSPHSLPPASSSAPAPPMRF 373
Query: 865 PLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNW 924
P + +SS+ + S++ S ++ A+Q+ + S P VS +P +
Sbjct: 374 PYSSSSSS---SAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN---QPPKY 427
Query: 925 DQNVQSMETQIDKAQAVTQPVP----LANKPVPAQSTFPSKTG 963
Q S+ +Q +Q P P LAN FP TG
Sbjct: 428 TQ--PSLPSQAVWSQGPPPPPPYGRLLANSNA-HPGPFPPSTG 467
Score = 38.1 bits (87), Expect = 0.094
Identities = 58/265 (21%), Positives = 88/265 (33%), Gaps = 40/265 (15%)
Query: 1094 PGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGS----RERIPPRRAGSRERGPPRG 1149
P G + + G +R P A P + GS R PP G R PP G
Sbjct: 625 PAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP---GYRGTSPPAG 681
Query: 1150 PGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNH------------GE 1197
PG+ + G GP P G + P PP AP + E
Sbjct: 682 PGTFKPGSPTVG----PGPLPPAGPSGLPSLPP-----PPAAPASGPPLSATQIKQEPAE 732
Query: 1198 ERGHEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHD 1257
E E P+ +P ++ D + D R D + P S
Sbjct: 733 EYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKL 792
Query: 1258 GDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLD 1317
+R + R+ + +E ER+ +R+ +R + E +R+ R +
Sbjct: 793 AKKRADLVEKVRREAEQRAREEKEREREREREKER------------EREKERELERSVK 840
Query: 1318 EQESQFRERDIPSLPPLPPLPPLPP 1342
+ + PSL P+P PP P
Sbjct: 841 LAQEGRAPVECPSLGPVPHRPPFEP 865
Score = 35.0 bits (79), Expect = 0.79
Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 29/139 (20%)
Query: 1508 PPGSYRPPPPM-----------GKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP 1556
P G + PPP G PP P+ P ++P PP P P
Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTK--PPTTPVGGGNLPSAPPPANFPHVTPN---L 301
Query: 1557 PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSS 1616
PPPP ++P +A S GL Q L S A LPP P
Sbjct: 302 PPPPALRPLNNA-------SASPPGL----GAQPLPGHLPSPHAMGQGMGGLPPGPEKG- 349
Query: 1617 IPPPGPVPMGMPPMSKPPP 1635
P P P +PP S P
Sbjct: 350 -PTLAPSPHSLPPASSSAP 367
Score = 32.3 bits (72), Expect = 5.1
Identities = 25/67 (37%), Positives = 28/67 (41%), Gaps = 10/67 (14%)
Query: 1508 PPGSYRPPP---PMGKPPGSIVR-PSAP-PARSSVPVTRPPVPIPPP-----PPPPPLPP 1557
P Y PPP P +PP S R P A SV T P+ PP PP PP
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 1558 PPPVIKP 1564
P P + P
Sbjct: 215 PHPQLYP 221
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 96.7 bits (239), Expect = 2e-19
Identities = 165/695 (23%), Positives = 224/695 (32%), Gaps = 126/695 (18%)
Query: 9 GGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68
G + Y PPP+ PP P P+++P +S + + +G+ + E +++ Q
Sbjct: 154 GPARPYHPPPLFPPSPQP-PDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQA---- 208
Query: 69 QKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQML 128
PP PP P + GG G PP P G A S
Sbjct: 209 -------------PPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSV----------- 244
Query: 129 HHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQ 188
GP G PP P S S PP +PP + P P+
Sbjct: 245 ----GGPNG-------GKQHPPPTTPISVSSSGASGAPPTKPPTT---PVGGGNL--PSA 288
Query: 189 PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS-------K 241
P P+ P L P P+ +++S S LP SP QG K
Sbjct: 289 PPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
Query: 242 SQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQH 301
LAP P S PP + ++ P+ + S+ A+ S+ +
Sbjct: 349 GPTLAPSPHSLPPAS-SSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP--------- 398
Query: 302 LLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVT-VPATSQVPESPS----SEEPPLPPP 356
P + P P P V+ P P PS S+ PP PPP
Sbjct: 399 -----------FPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP 447
Query: 357 NEEV-------PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKH 409
+ P P PP A+ + H HQQ Q Q Q+
Sbjct: 448 YGRLLANSNAHPGPFPPST--------GAQSTAHPPVSTHHHHHQQ-----QQQQQQQQQ 494
Query: 410 TQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSY 469
Q QQ Q + PPP ++ H+ L R + H
Sbjct: 495 QQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSL--RPYP--PGPAHLP 550
Query: 470 PHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPP 529
P Q+ Y + ++ S S+ + S P PY P P
Sbjct: 551 PPHSQVS-YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP----SPSQGPQGAPYPFPPVP 605
Query: 530 LPTMPPPVLPPSLPPPVMPPALPATVPPPGMPP----PVMPPSLPTSVPP---PGMPPSL 582
T L + PA T PPG PP P + T+ PP PG PPS
Sbjct: 606 TVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSF 665
Query: 583 SSAGPPPV--LPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQ 640
+ PP PP AGP P S T P PLPP + P PPP P
Sbjct: 666 RTGTPPGYRGTSPP----AGPGTFKPG---SPTVGPG--PLPPAGPSGLPSLPPPPAAPA 716
Query: 641 GIPP-QLTAAPVPPASSSQSSQVPEKPRPALLPTP 674
PP T PA ++ + P P + P P
Sbjct: 717 SGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Score = 91.7 bits (226), Expect = 7e-18
Identities = 102/380 (26%), Positives = 133/380 (35%), Gaps = 67/380 (17%)
Query: 528 PPLPTMPPPVLPPSLPPPVMPPALP-------ATVPPPGMPPPVMPPSLPTSVPPPGMP- 579
P P PPP+ PPS PP P P +V P G P+ PP+ PPG P
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 580 --PSLSSAGPPPVLPPPSLSSAG----------------PPPVLP---PPSLSSTAPPPV 618
P L G VL P + G PPP P S +S APP
Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK 274
Query: 619 MPLPPLSSATPPPGIPP---PGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPV 675
P P+ P PP P V +PP P+ AS+S + +P P LP+P
Sbjct: 275 PPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPG-LGAQPLPGHLPSPH 333
Query: 676 SFGSA----PPTTYHPPLQSAGPSE--QVNSKAPLSKSALPYSSFSSDQGLGESSAAPS- 728
+ G PP P + P +S AP PYSS SS SS++ S
Sbjct: 334 AMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSS 393
Query: 729 ---QPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRF 785
P A + +P PP +S S + P++ P +GP P P
Sbjct: 394 SSASPFPASQALPSYPHSF---PPPTSLSVSNQPPKYTQP-SLPSQAVWSQGPPPPPP-- 447
Query: 786 EGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFG 845
G + + G P +Q P S Q +
Sbjct: 448 ------------YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ------Q 489
Query: 846 QQHQQQPKSQAEPLSGNKEP 865
QQ QQQ + Q + GN P
Sbjct: 490 QQQQQQQQQQQQQHHGNSGP 509
Score = 74.7 bits (182), Expect = 9e-13
Identities = 105/374 (28%), Positives = 135/374 (36%), Gaps = 61/374 (16%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLP------PPVMPPALPATVPPPGMPPPVM 565
G PPP P S + + PP PP+ P P PPA V P PPP +
Sbjct: 249 GGKQHPPPTTPIS-VSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPAL 307
Query: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLS 625
P S PPG L + P LP P G + P P T P LPP S
Sbjct: 308 RPLNNASASPPG----LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPAS 363
Query: 626 SATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTY 685
S+ P PP P +AA +SSS SS P AL P SF PPT+
Sbjct: 364 SSAP---APPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSF--PPPTSL 418
Query: 686 ----HPP--LQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPV 739
PP Q + PS+ V S+ P PY L S+A P
Sbjct: 419 SVSNQPPKYTQPSLPSQAVWSQGP--PPPPPYGRL-----LANSNAHP------------ 459
Query: 740 RSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEG 799
G P S P ++ + + + + + + GN P P
Sbjct: 460 --GPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN-SGPPPPGAFP 516
Query: 800 HPAEGTKSKWGMIPRGPASQFYITPST-SLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEP 858
HP EG S A + ++PS SL P GP P H Q SQA P
Sbjct: 517 HPLEGGSSH-------HAHPYAMSPSLGSLRPYPPGPAHLPP------PHSQVSYSQAGP 563
Query: 859 LSGNKEPLADTSSN 872
N P++ +S++
Sbjct: 564 ---NGPPVSSSSNS 574
Score = 73.6 bits (179), Expect = 2e-12
Identities = 90/326 (27%), Positives = 117/326 (35%), Gaps = 59/326 (18%)
Query: 12 SHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71
S PPPP P +A A PGP + ST + + + H Q QQ QQ Q+Q
Sbjct: 439 SQGPPPPPPYGRLLANSNAHPGP-FPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497
Query: 72 MQCVLQPHH---LPPPPLPPPPVMPGGGYGDWQP--PPPPM----PPPPGPALSYQKQQQ 122
Q Q HH PPPP P + GG P P + P PPGPA
Sbjct: 498 QQ--QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPA-----HLP 550
Query: 123 YKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPP----T 178
H + + + GP G P S S GSY S PQ P +PP T
Sbjct: 551 PPHSQVSYSQAGPNG--PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVT 608
Query: 179 SSQPYLPPAQPSPSQSPPSQSYLAP--TPSYSSSSSSSQSYLSHS-QSYLPSSQAS---- 231
+S L + + SP +P P Y + S +Y + + Y P S S
Sbjct: 609 TSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTG 668
Query: 232 ------------------PSRPS--------QGHSKSQLLAPP---PPSAPPGNKTTVQQ 262
P P+ G S L PP P S PP + T ++Q
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQ 728
Query: 263 EPLESGAKNKSTEQQQAAPEPDPSTM 288
EP E +S +P P P +
Sbjct: 729 EPAEEYETPESPVPPARSPSPPPKVV 754
Score = 72.4 bits (176), Expect = 4e-12
Identities = 165/693 (23%), Positives = 218/693 (31%), Gaps = 148/693 (21%)
Query: 103 PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ 162
PPP PP P P S +Q + + P + P +P E PP S M +
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEP-------HPSVTPTGYHAPME----PPTSRMFQAP 209
Query: 163 SYMPPPQPPPSYYPP-TSSQPYLPPAQP-----SPSQSPPSQSYLAPTPSYSSSSSSSQS 216
PPP P YP T PP P + S P+ P P+ S SSS +
Sbjct: 210 PGAPPPHP--QLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGA 267
Query: 217 YLSHSQSYLPSSQASPSRP-SQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTE 275
S A P++P + L + PPP+ P + P N S
Sbjct: 268 -----------SGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASAS 316
Query: 276 QQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPG-HKKGPVVAKDTPEPVKEEV 334
+P P HLP H G + P P K
Sbjct: 317 PPGLGAQPLPG-------------------------HLPSPHAMGQGMGGLPPGPEKGPT 351
Query: 335 TVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQ 394
P SP S LPP + P P P P S A AA++
Sbjct: 352 LAP-------SPHS----LPPASSSAPAP-PMRFPYSSSSSSSA------AASSSSSSSS 393
Query: 395 QHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQE 454
F Q L Y PP ++SV Q Y Q ++ +
Sbjct: 394 SSASPFP----------ASQALPSYPHSFPPPT---SLSVSNQPPKYTQPSLPSQAVWSQ 440
Query: 455 -------WEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMK 507
+ R +P Q + H Q Q++ Q +
Sbjct: 441 GPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQ 500
Query: 508 NQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVP-PPGMPPPVMP 566
Q+ GN PPP P PL P M P+L + P PPG
Sbjct: 501 QQHHGNSGPPPP----GAFPHPLEGGSSH----HAHPYAMSPSLGSLRPYPPG------- 545
Query: 567 PSLPTSVPPPGMPPSLSSAGP--PPVLPPPSLSSAGP----PPVLPPPSLSST-APPPVM 619
P +PPP S S AGP PPV + SS+ P P PS AP P
Sbjct: 546 ---PAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFP 602
Query: 620 PLPPLSS------------ATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPR 667
P+P +++ A+ P G P G PP AP P A + + P +
Sbjct: 603 PVPTVTTSSATLSTVIATVASSPAGYKTAS-PPGPPPYGKRAPSPGAYKTAT---PPGYK 658
Query: 668 PALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAP 727
P +P SF + P Y AGP + LP + S L AAP
Sbjct: 659 PG---SPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAP 715
Query: 728 SQPITAVKDMPVRSGGLLPDPPRSSYLESPRGP 760
+ P S + P Y E+P P
Sbjct: 716 ASG-------PPLSATQIKQEPAEEY-ETPESP 740
Score = 68.6 bits (166), Expect = 6e-11
Identities = 112/454 (24%), Positives = 158/454 (34%), Gaps = 109/454 (24%)
Query: 9 GGSSHY----------------PPPPVPPPPP---VALPEASP-GPGYSSSTTPAAPSSS 48
GGSSH+ PP P PPP V+ +A P GP SSS+ ++ +S
Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
Query: 49 GFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVM---------------- 92
G S+ H + Q Q P P PP P +
Sbjct: 581 G--SYPCSHPSPSQGPQG---------------APYPFPPVPTVTTSSATLSTVIATVAS 623
Query: 93 PGGGYGDWQPPPPP----MPPPPGPALSYQKQQQYKHQMLHHQRDG-PPGLVPMELESPP 147
GY PP PP P PG A YK R G PPG
Sbjct: 624 SPAGYKTASPPGPPPYGKRAPSPG-AYKTATPPGYKPGSPPSFRTGTPPGY-------RG 675
Query: 148 ESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPP-SQSYLAPTPS 206
SPP PG++ P S + P P PP S P LPP +P+ PP S + + P+
Sbjct: 676 TSPPAGPGTFKPGSPTVGPGPLPPAG----PSGLPSLPPPPAAPASGPPLSATQIKQEPA 731
Query: 207 YSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGH-------------SKSQLLAPPPPSAP 253
+ S + S S P PS SQ ++S L P +
Sbjct: 732 EEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSK 791
Query: 254 PGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHL 313
K E + A+ ++ E+++ E + +E+++ R L+ + R V
Sbjct: 792 LAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVEC 851
Query: 314 PGHKKGPVVAKDTPEPVKEEVTV--------PATSQVPE-------SPSSEEPPLPPPNE 358
P GPV + EP TV PA + E SP + P P
Sbjct: 852 P--SLGPVPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLG 909
Query: 359 EVP--------PPLPPEEPQSEDPEEDARLKQLQ 384
V P L +P + + E +AR + L+
Sbjct: 910 AVDPGLLGYNVPALYSSDPAAREREREARERDLR 943
Score = 64.3 bits (155), Expect = 1e-09
Identities = 100/396 (25%), Positives = 145/396 (36%), Gaps = 106/396 (26%)
Query: 1499 TSSRPG------MYPPPGSYRPPPPMGKPPGS--IVRPSAPPA-RSSVPVTRP------- 1542
T+S PG P PG+Y+ P G PGS R PP R + P P
Sbjct: 630 TASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS 689
Query: 1543 ----PVPIPPPPPP--PPLPPPP--PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSE 1594
P P+PP P P LPPPP P P SA ++
Sbjct: 690 PTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSA------------------------TQ 725
Query: 1595 FKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVE 1654
K E A P P PP S PPP V + P Q+ + D N
Sbjct: 726 IKQEPAEEYETPESPVPPARSPSPPPKVVDV-------PSHASQSARFNKHLDRGFNSCA 778
Query: 1655 Q-----IPY-GERITLRPDPLPERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRD 1708
+ +P G ++ + L E+ E E QR R ++ER+RE R+
Sbjct: 779 RSDLYFVPLEGSKLAKKRADLVEKVRREAE---QRAREEKERERE-------------RE 822
Query: 1709 FKRDRETHRDRDRDRGVIDYDRDRFDRE--------RRPRDDRAQSYRDKKDHSSSRRGG 1760
+++RE ++R+ +R V R E RP + + + G
Sbjct: 823 REKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYL-----G 877
Query: 1761 FDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPA----------PSLSHQPPPAPRV 1810
D P+ S+ Y P + R +P +PL A P+L P A
Sbjct: 878 PDTPALRTLSE---YARPHVMSPGNRNHP-FYVPLGAVDPGLLGYNVPALYSSDPAARER 933
Query: 1811 EKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSG 1846
E++ +++ D LK PG E +P + + G+PG G
Sbjct: 934 EREARERDLRDRLK-PGFEVKPSELEP-LHGVPGPG 967
Score = 60.8 bits (146), Expect = 1e-08
Identities = 44/125 (35%), Positives = 52/125 (41%), Gaps = 15/125 (12%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLPPPVM---PPALPATVPPPGMPPPVMPPSLPTSV 573
PPP+ + P T PP P PP PP T PP G P P PT
Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG--PGTFKPGSPTVG 693
Query: 574 PPPGMPPSLSSAGPP--PVLPPPSLSSAGPPPVLPPPSLSSTA---PPPVMPLPPLSSAT 628
P P +PP AGP P LPPP + A PP+ A P P+PP S +
Sbjct: 694 PGP-LPP----AGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPS 748
Query: 629 PPPGI 633
PPP +
Sbjct: 749 PPPKV 753
Score = 45.8 bits (107), Expect = 4e-04
Identities = 33/84 (39%), Positives = 40/84 (47%), Gaps = 6/84 (7%)
Query: 517 PPPFVPYSQM--PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVP 574
P F P S P PLP P LP SLPPP PA PA+ PP P+ P
Sbjct: 682 PGTFKPGSPTVGPGPLPPAGPSGLP-SLPPP---PAAPASGPPLSATQIKQEPAEEYETP 737
Query: 575 PPGMPPSLSSAGPPPVLPPPSLSS 598
+PP+ S + PP V+ PS +S
Sbjct: 738 ESPVPPARSPSPPPKVVDVPSHAS 761
Score = 44.3 bits (103), Expect = 0.001
Identities = 56/233 (24%), Positives = 86/233 (36%), Gaps = 52/233 (22%)
Query: 1483 PQMADHLPPQESR--LQNTSSRP---GMYPPPGSYRPPPPMGK-----PPGSIVRPSAPP 1532
P + +LPP + L N S+ P G P PG P MG+ PPG P+ P
Sbjct: 295 PHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP 354
Query: 1533 ARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLN 1592
+ S+ PP P PP+ P +S+ S ++
Sbjct: 355 SPHSL------------PPASSSAPAPPMRFPYSSSSSSSAAASSS------SSSSSSSA 396
Query: 1593 SEFKSETAAIPSAPVLPPPPVHSSI---PPPGPVP---------MGMPPMSKPPPVQQTV 1640
S F + + A+PS P PPP S+ PP P G PP PPP
Sbjct: 397 SPFPA-SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPP---PPP----- 447
Query: 1641 DYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDRE 1693
+GR ++ + P+ + P ST H Q+ + +++ ++
Sbjct: 448 ---YGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQ 497
Score = 43.9 bits (102), Expect = 0.002
Identities = 78/343 (22%), Positives = 118/343 (34%), Gaps = 45/343 (13%)
Query: 636 PGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTY---------- 685
P P PP +P PP S+ + + +P P++ PT PPT+
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 686 -HPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGL 744
HP L G ++ K SS G G+ P+ PI+ + G
Sbjct: 215 PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNG-GKQHPPPTTPISVSSS---GASGA 270
Query: 745 LPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEG 804
P P ++ + P P F + P P R N P P G
Sbjct: 271 PPTKPPTTPVGGGNLPSAPPPANFPHVTPNL--PPPPALRPLNNASASP-------PGLG 321
Query: 805 TKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKE 864
+ G +P A + GP+ KGP A H P S + P +
Sbjct: 322 AQPLPGHLPSPHAM------GQGMGGLPPGPE-KGPTLA-PSPHSLPPASSSAPAPPMRF 373
Query: 865 PLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNW 924
P + +SS+ + S++ S ++ A+Q+ + S P VS +P +
Sbjct: 374 PYSSSSSS---SAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSN---QPPKY 427
Query: 925 DQNVQSMETQIDKAQAVTQPVP----LANKPVPAQSTFPSKTG 963
Q S+ +Q +Q P P LAN FP TG
Sbjct: 428 TQ--PSLPSQAVWSQGPPPPPPYGRLLANSNA-HPGPFPPSTG 467
Score = 38.1 bits (87), Expect = 0.094
Identities = 58/265 (21%), Positives = 88/265 (33%), Gaps = 40/265 (15%)
Query: 1094 PGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGS----RERIPPRRAGSRERGPPRG 1149
P G + + G +R P A P + GS R PP G R PP G
Sbjct: 625 PAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP---GYRGTSPPAG 681
Query: 1150 PGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWNH------------GE 1197
PG+ + G GP P G + P PP AP + E
Sbjct: 682 PGTFKPGSPTVG----PGPLPPAGPSGLPSLPP-----PPAAPASGPPLSATQIKQEPAE 732
Query: 1198 ERGHEEFPLDGRNAPMERERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHD 1257
E E P+ +P ++ D + D R D + P S
Sbjct: 733 EYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKL 792
Query: 1258 GDRRGPWWDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLD 1317
+R + R+ + +E ER+ +R+ +R + E +R+ R +
Sbjct: 793 AKKRADLVEKVRREAEQRAREEKEREREREREKER------------EREKERELERSVK 840
Query: 1318 EQESQFRERDIPSLPPLPPLPPLPP 1342
+ + PSL P+P PP P
Sbjct: 841 LAQEGRAPVECPSLGPVPHRPPFEP 865
Score = 35.0 bits (79), Expect = 0.79
Identities = 39/139 (28%), Positives = 47/139 (33%), Gaps = 29/139 (20%)
Query: 1508 PPGSYRPPPPM-----------GKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP 1556
P G + PPP G PP P+ P ++P PP P P
Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTK--PPTTPVGGGNLPSAPPPANFPHVTPN---L 301
Query: 1557 PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSS 1616
PPPP ++P +A S GL Q L S A LPP P
Sbjct: 302 PPPPALRPLNNA-------SASPPGL----GAQPLPGHLPSPHAMGQGMGGLPPGPEKG- 349
Query: 1617 IPPPGPVPMGMPPMSKPPP 1635
P P P +PP S P
Sbjct: 350 -PTLAPSPHSLPPASSSAP 367
Score = 32.3 bits (72), Expect = 5.1
Identities = 25/67 (37%), Positives = 28/67 (41%), Gaps = 10/67 (14%)
Query: 1508 PPGSYRPPP---PMGKPPGSIVR-PSAP-PARSSVPVTRPPVPIPPP-----PPPPPLPP 1557
P Y PPP P +PP S R P A SV T P+ PP PP PP
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPP 214
Query: 1558 PPPVIKP 1564
P P + P
Sbjct: 215 PHPQLYP 221
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 96.7 bits (239), Expect = 2e-19
Identities = 145/624 (23%), Positives = 219/624 (35%), Gaps = 94/624 (15%)
Query: 196 PSQSYLAPTPSYSSSSSSSQSYLSHS-QSYLPSSQASPSRPSQGHS-----KSQLLAPPP 249
PS+ + S S + HS + PSS S R +G + + P P
Sbjct: 103 PSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLP 162
Query: 250 PSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRT 309
P T + P + + QA E PQ + R S +R+
Sbjct: 163 PPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRS---RACEPSTPRRS 219
Query: 310 KVHLPGHKKGPVVAKDTPEPVKEE-VTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEE 368
+ PG GP K V E VT+P PE P PP+ P + E
Sbjct: 220 RGRPPGRPAGPCRRKQQAVVVAEAAVTIPK----PEPP----PPVVPVKHQTGSWKCKEG 271
Query: 369 PQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPH 428
P P R Q G + +G + + + + +++
Sbjct: 272 P-GPGPGTPRRGGQSSRGGR----------GGRGRGRGGGLPFVIKFVSRAKKVKMGQLS 320
Query: 429 IQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGH 488
+ S Q +H E Q Q + W++Q +++ ++ E++ K +G
Sbjct: 321 LGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEE-EKKEEEEKDKEGE 379
Query: 489 MKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMP 548
K ++ +E + + + + + PP P +PPP + PPP+ PP PPPV P
Sbjct: 380 EKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPP-PPPVSP 438
Query: 549 PALPATVPPPGM------PPPVMPPSLPTSVPPPGMPPS------LSSAGP---PPVLPP 593
P LP+ PPP PPPV+P + P + PS + AGP P P
Sbjct: 439 PPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPT 498
Query: 594 PSLSSAGPPPVLPPPSLSSTA------------------------------PPPVMPLPP 623
PS ++ GPP P + ST PP P
Sbjct: 499 PSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVE 558
Query: 624 LSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGS---- 679
+S PP P VPQ P + + P P S +PEK R L + S
Sbjct: 559 VSPVLRPPITTSPPVPQE-PAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRE 617
Query: 680 ---APPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKD 736
PP PP S P+ +S+ PL A ++ + + ES P P +
Sbjct: 618 LPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTP--PPLGAPE 675
Query: 737 MPVRSGGLLPDPPRSSYLESPRGP 760
P P+PP + +SP P
Sbjct: 676 APE------PEPPPAD--DSPAEP 691
Score = 77.0 bits (188), Expect = 2e-13
Identities = 99/391 (25%), Positives = 136/391 (34%), Gaps = 66/391 (16%)
Query: 78 PHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPG 137
P PPPPLPPP P PPPPP+ PPP P+ Q+ Q + PP
Sbjct: 409 PAPSPPPPLPPPSTSPPPPL--CPPPPPPVSPPPLPSPPPPPAQE-------EQEESPPP 459
Query: 138 LVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPS 197
+VP PP+ P + P P PT S P + SP+ +P S
Sbjct: 460 VVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPP--TPTPSTATGGPPEDSPTVAPKS 517
Query: 198 QSYL-------APTPSYSSSS--SSSQSYLSHSQSYLPSSQASP-------SRPSQGHSK 241
++L P S SS + + ++ P + SP + P
Sbjct: 518 TTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEP 577
Query: 242 SQLLAPP----PPSAP---PGNKTTVQQEP-LESGAKNKSTEQQQAAPEPDPSTMTPQEQ 293
+ + +PP PPS P P + ++ +EP + + AP P P+ P
Sbjct: 578 APVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAP 637
Query: 294 QQYWYRQHLLSLQQRT--KVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP 351
R LL Q T + HL + E V P PE+P E P
Sbjct: 638 ATSSRRPLLLRAPQFTPSEAHL---------------KIYESVLTPPPLGAPEAPEPEPP 682
Query: 352 PLPPPNEEVPP---------PLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQY 402
P E P LP P P + A ++ Q Q +
Sbjct: 683 PADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLL---- 738
Query: 403 QGIMQKHTQ-LQQILQQYQQIIQPPPHIQTM 432
Q + TQ L Q L Q +QPPP Q M
Sbjct: 739 QPLQALQTQLLPQALPPPQPQLQPPPSPQQM 769
Score = 76.3 bits (186), Expect = 3e-13
Identities = 101/417 (24%), Positives = 147/417 (35%), Gaps = 110/417 (26%)
Query: 15 PPPPV--PPPPPVA---LPEASPGPGYSS---STTPAAPSSSGFMSFREQHLAQLQQLQQ 66
PPPP+ PPPPPV+ LP P P S P P++ R++ L Q+
Sbjct: 424 PPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCS----RKRGRPPLTPSQR 479
Query: 67 MHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQ 126
++ + + PP P P GG PP P + ++ K +
Sbjct: 480 AEREAARAGPEG---TSPPTPTPSTATGG-------PPEDSPTVAPKSTTFLKNIRQFIM 529
Query: 127 MLHHQRDGPPGLVPMEL--ESPPESPPV-------PPGSYMPP-SQSYMPPPQPPPSYYP 176
+ R P E PP+ P V PP + PP Q P P PP + P
Sbjct: 530 PVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP 589
Query: 177 PTSSQPY---------------------LPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQ 215
P++ P LPP P+P P AP+P + ++SS +
Sbjct: 590 PSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPP------APSPPPAPATSSRR 643
Query: 216 SYLSHSQSYLPSSQASPSRPSQGHSK--SQLLAPPPPSAPPGNKTTVQQEPLESGAKNKS 273
L + + PS + H K +L PPP AP
Sbjct: 644 PLLLRAPQFTPS---------EAHLKIYESVLTPPPLGAP-------------------- 674
Query: 274 TEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEE 333
+ PEP P+ +P E + V H P A PVK E
Sbjct: 675 ---EAPEPEPPPADDSPAEPEP-------------RAVGRTNHLSLPRFAPVVTTPVKAE 718
Query: 334 VT---VPATSQVPESPSSEEPPLPPPNEEV-PPPLPPEEPQSEDPEEDARLKQLQAA 386
V+ PA S P++ + PL ++ P LPP +PQ + P ++ L+ A
Sbjct: 719 VSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKA 775
Score = 65.9 bits (159), Expect = 4e-10
Identities = 89/300 (29%), Positives = 113/300 (37%), Gaps = 54/300 (18%)
Query: 529 PLPTMPPPV-LPPSLPPPVMPPALPATVPP-PGMPPPVMPPSLPTSVPPPGMPPSLSSA- 585
P P+ PP P L V+ P P P + PP+ P S S PPP P S S A
Sbjct: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDS--GSAPPPA-PRSFSGAR 1864
Query: 586 ----GPPPVLPPPSLSSAGPPPVLPPPSLSS----TAPPPVMPLPPLSSATPPPGIPPPG 637
P P S GP P PS + T P P PP S P P P P
Sbjct: 1865 IKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRP- 1923
Query: 638 VPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAP--PTTYHPPLQSAGPS 695
PP A+ PP +S +VP TP S AP P PP + GP
Sbjct: 1924 -----PPSRWAS--PPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPD 1976
Query: 696 -EQVNSKAPLSKSALPYSSF------------------SSDQGLGESSAAPSQPITAVKD 736
E + + LS + L +++ SS G G+SS S P +
Sbjct: 1977 FEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIH 2036
Query: 737 MP---VRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGP 793
P V + GL P S+ +PR + DG D G+ E + PR +G P GP
Sbjct: 2037 FPVTVVSAPGLAP----SATPGAPRIEQLDG----VDDGTDSEAEAVQQPRGQGTPPSGP 2088
Score = 64.7 bits (156), Expect = 9e-10
Identities = 79/298 (26%), Positives = 105/298 (35%), Gaps = 43/298 (14%)
Query: 541 SLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSS-- 598
SLPP PP + P G+ P+ + P + S GP P P P+ S
Sbjct: 2135 SLPPA--PPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKII 2192
Query: 599 ------------AG-----PPPVLP---PPSLSSTAPPP-VMPLPPLSSATPPPGIPPPG 637
AG PPPV PP++S TAP +P PL P G+ P
Sbjct: 2193 LVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPA 2252
Query: 638 VPQGIPPQLTAAPVPPAS-----------SSQSSQVPEKPRPALLPTPVSFGSAPPTTYH 686
P PP PAS S+ S + P P P P G A T
Sbjct: 2253 PPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQ 2312
Query: 687 PPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLP 746
P +G +V K P + L + GE S P Q + + +P +P
Sbjct: 2313 VPGLGSGGFSRVRMKTPTVRGVLDLD--RPGEPAGEESPGPLQERSPLLPLPEDGPPQVP 2370
Query: 747 DPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEG 804
D P LES + + G E S E P P + + GP R+E +G
Sbjct: 2371 DGPPDLLLES-QWHHYSG----EASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDG 2423
Score = 63.2 bits (152), Expect = 3e-09
Identities = 68/252 (26%), Positives = 93/252 (36%), Gaps = 43/252 (17%)
Query: 142 ELESPPESPPVP--PGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQS 199
+L PP +PP P P PPS S PP PPP PP S P LP P P+Q +S
Sbjct: 400 KLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPP---PPPVSPPPLPSPPPPPAQEEQEES 456
Query: 200 YLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTT 259
P P ++ S + P PSQ + A P ++PP
Sbjct: 457 ---PPPVVPATCSRKRG-------------RPPLTPSQRAEREAARAGPEGTSPP----- 495
Query: 260 VQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKG 319
P S A E P +T +Q + ++S + + P
Sbjct: 496 ---TPTPSTATGGPPEDSPTV-APKSTTFLKNIRQ---FIMPVVSARSSRVIKTPRR--- 545
Query: 320 PVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVP-PPLPPEEPQSEDPEEDA 378
+ +D P+P K EV S V P + PP+P VP PP P P + P +
Sbjct: 546 -FMDEDPPKPPKVEV-----SPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEK 599
Query: 379 RLKQLQAAAAHW 390
R L+ W
Sbjct: 600 RRSILREPTFRW 611
Score = 60.5 bits (145), Expect = 2e-08
Identities = 81/303 (26%), Positives = 109/303 (35%), Gaps = 46/303 (15%)
Query: 525 QMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSS 584
++PPP P PPP P P P P + P P + SV P PP +
Sbjct: 617 ELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTP--PPLGAP 674
Query: 585 AGPPPVLPPPSLSSAGPPP--VLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGI 642
P P PP S A P P V LS PV+ P + +P P + G
Sbjct: 675 EAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGA---PALSNG- 730
Query: 643 PPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSA---------- 692
PQ A + P + Q+ +P+ AL P P PPL+ A
Sbjct: 731 -PQTQAQLLQPLQALQTQLLPQ----ALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPL 785
Query: 693 -GPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRS 751
G E++ S +K L F DQ + AA MP+ GG + + +
Sbjct: 786 SGVEEKMFSLLKRAKVQL----FKIDQQQQQKVAA---------SMPLSPGGQMEEVAGA 832
Query: 752 SYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYE-GHPAEGTKSKWG 810
S R GP R ED + RP GP + GPR ++ H A
Sbjct: 833 VKQISDR-----GPVRSEDESVEAKRERPSGPE---SPVQGPRIKHVCRHAAVALGQARA 884
Query: 811 MIP 813
M+P
Sbjct: 885 MVP 887
Score = 56.2 bits (134), Expect = 3e-07
Identities = 36/106 (33%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
Query: 1470 KEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYR---PPPPMGKPPGSIV 1526
K+Q QK+ D E + + + + + M P PPPP+ PP
Sbjct: 355 KKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPL-TPPAPSP 413
Query: 1527 RPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQE 1572
P PP P T PP P+ PPPPPP PPP P P + EQE
Sbjct: 414 PPPLPP-----PSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQE 454
Score = 54.3 bits (129), Expect = 1e-06
Identities = 38/127 (29%), Positives = 57/127 (44%), Gaps = 22/127 (17%)
Query: 1458 KAAQELKMLREQKEQLQKMKDFGSEPQ---MADHLPPQESRLQNTSSRPGMYPPPGSYRP 1514
K Q+L E+K++ ++ G E + +A+ + P + + P + PP S P
Sbjct: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS--P 413
Query: 1515 PPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPP--------PPVIKPQT 1566
PPP+ P S P PP PP P+ PPP P P PPP PP + P T
Sbjct: 414 PPPLPPPSTSPPPPLCPP---------PPPPVSPPPLPSPPPPPAQEEQEESPPPVVPAT 464
Query: 1567 SAVEQER 1573
+ ++ R
Sbjct: 465 CSRKRGR 471
Score = 51.6 bits (122), Expect = 8e-06
Identities = 46/157 (29%), Positives = 58/157 (36%), Gaps = 24/157 (15%)
Query: 1487 DHLPPQESRLQ-NTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAP-------------P 1532
D PP+ +++ + RP + P + P P+ PP + PS P P
Sbjct: 548 DEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP 607
Query: 1533 ARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGL- 1591
+TR P PP PPPPP P PPP P TS+ F T E L
Sbjct: 608 TFRWTSLTRELPPPPPAPPPPPAPSPPPA--PATSSRRPLLLRAPQF-----TPSEAHLK 660
Query: 1592 --NSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMG 1626
S P AP PPP S P P +G
Sbjct: 661 IYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVG 697
Score = 50.4 bits (119), Expect = 2e-05
Identities = 49/156 (31%), Positives = 62/156 (39%), Gaps = 24/156 (15%)
Query: 1516 PPMGKPPGSIVRPSA-PPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERW 1574
PP KPP V P PP +S PV + P P+P PP P PP PV P+ +
Sbjct: 551 PP--KPPKVEVSPVLRPPITTSPPVPQEPAPVPS-PPRAPTPPSTPVPLPEK---RRSIL 604
Query: 1575 DEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634
E +F + S T +P P PPPP S PPP P P+
Sbjct: 605 REPTF--------------RWTSLTRELPPPPPAPPPPPAPS-PPPAPATSSRRPLLLRA 649
Query: 1635 PVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLP 1670
P Q T H + I + + P G P+P P
Sbjct: 650 P-QFTPSEAHLK-IYESVLTPPPLGAPEAPEPEPPP 683
Score = 47.0 bits (110), Expect = 2e-04
Identities = 53/192 (27%), Positives = 59/192 (30%), Gaps = 59/192 (30%)
Query: 533 MPPPVLPPSLPPPVMPPALPATVPPPG--------------MPPPVMPPSLPTSVPPPGM 578
+PPPV P LPP + P A + PPG PPP PP P
Sbjct: 2211 VPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPAS 2270
Query: 579 PP---------SLSSAGPPPVLPP-------------------PSLSSAG-------PPP 603
PP S S PP PP P L S G P
Sbjct: 2271 PPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPT 2330
Query: 604 V-------LPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASS 656
V P +P P+ PL P P PP VP G P L + S
Sbjct: 2331 VRGVLDLDRPGEPAGEESPGPLQERSPL---LPLPEDGPPQVPDGPPDLLLESQWHHYSG 2387
Query: 657 SQSSQVPEKPRP 668
SS E P P
Sbjct: 2388 EASSSEEEPPSP 2399
Score = 44.7 bits (104), Expect = 0.001
Identities = 27/93 (29%), Positives = 35/93 (37%), Gaps = 42/93 (45%)
Query: 1546 IPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSA 1605
+PPPP PP P PPP + P +++ P
Sbjct: 401 LPPPPLTPPAPSPPPPLPPPSTS----------------------------------PPP 426
Query: 1606 PVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQ 1638
P+ PPPP PP P P+ PP PPP Q+
Sbjct: 427 PLCPPPP-----PPVSPPPLPSPP---PPPAQE 451
Score = 43.5 bits (101), Expect = 0.002
Identities = 100/430 (23%), Positives = 131/430 (30%), Gaps = 110/430 (25%)
Query: 34 PGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMP 93
PG + S TP AP + QL + + + V QP PP P V
Sbjct: 2045 PGLAPSATPGAP-----------RIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRA 2093
Query: 94 G--GGYGDWQPPPPPMPP-------------------------PPGPALSY--QKQQQYK 124
G G GD PP +P PP P L+ Q Q
Sbjct: 2094 GVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLT 2153
Query: 125 HQMLHHQRD-----GPPGLVPMELESPPESP-------------------------PVPP 154
R G PG+ + L PE P PVPP
Sbjct: 2154 ASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPP 2213
Query: 155 GSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPA---QPSPSQSPPSQSYLAPTPSYSSSS 211
PP + P P PP LP +P+P PP P SS
Sbjct: 2214 PVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPP------PLTLVLSSG 2267
Query: 212 SSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAP------PGNKTTVQQEPL 265
+S P QA + S APPP AP ++ T Q L
Sbjct: 2268 PAS-----------PPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGL 2316
Query: 266 ESGAKNK---STEQQQAAPEPD-PSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPV 321
SG ++ T + + D P +E LQ+R+ + LP + GP
Sbjct: 2317 GSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPG--------PLQERSPL-LPLPEDGPP 2367
Query: 322 VAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLK 381
D P + E S S S EEPP P E P + E ED
Sbjct: 2368 QVPDGPPDLLLESQWHHYSGEASS-SEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSV 2426
Query: 382 QLQAAAAHWQ 391
+ ++ W+
Sbjct: 2427 EAESLEGAWR 2436
Score = 41.2 bits (95), Expect = 0.011
Identities = 55/206 (26%), Positives = 78/206 (37%), Gaps = 45/206 (21%)
Query: 123 YKHQMLHHQRDGPPGLVPMELESPPESPPV---------PPGSYMPPSQSYMPPPQPPPS 173
Y+ ++L ++ GP P LE+ E+ + PPG PP + + P P
Sbjct: 1776 YRCRILEYRPWGPRE-EPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPER 1834
Query: 174 YYPPTSSQPYL-------PPAQP-------------SPSQSPPSQSYLAPTPSYSSSSSS 213
+ P + P L PP P SPS+ P P PS S SS
Sbjct: 1835 HSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSS- 1893
Query: 214 SQSYLSHSQSYLPS--SQASPSRPSQGHSKSQLLAPPPPS--APPGNKTTVQ---QEPLE 266
L+H ++P+ P+ P + S L PPPS A P KT+ Q P
Sbjct: 1894 ----LTH---HIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTS 1946
Query: 267 SGAKNKSTEQQQAAPEPDPSTMTPQE 292
T + A P P PS P++
Sbjct: 1947 VVTALTPTSGELAPPGPAPSPPPPED 1972
Score = 40.8 bits (94), Expect = 0.014
Identities = 43/179 (24%), Positives = 59/179 (32%), Gaps = 34/179 (18%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRP----SAPP------------- 1532
PP +TS P + PPP PPP+ PP + S PP
Sbjct: 413 PPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472
Query: 1533 ------------ARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSA----VEQERWDE 1576
AR+ T PP P P P P P + P+++ + Q
Sbjct: 473 PLTPSQRAEREAARAGPEGTSPPTPTPSTATGGP-PEDSPTVAPKSTTFLKNIRQFIMPV 531
Query: 1577 DSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
S + E + + +PVL PP S P P P+ PP + PP
Sbjct: 532 VSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP 590
Score = 40.8 bits (94), Expect = 0.014
Identities = 28/93 (30%), Positives = 33/93 (35%), Gaps = 2/93 (2%)
Query: 1480 GSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPS--APPARSSV 1537
GS + H+P R P P + RPPP P P PP S V
Sbjct: 1889 GSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVV 1948
Query: 1538 PVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVE 1570
P PP P P PPPP + P +E
Sbjct: 1949 TALTPTSGELAPPGPAPSPPPPEDLGPDFEDME 1981
Score = 40.4 bits (93), Expect = 0.019
Identities = 44/159 (27%), Positives = 56/159 (35%), Gaps = 38/159 (23%)
Query: 1515 PPPMGKPP-GSIVRPSAP--------PARSSVPVTRPPVPIPPPPPPP--------PLPP 1557
PPP+ +PP + P+AP P +PV P PPPPPPP P P
Sbjct: 2212 PPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASP 2271
Query: 1558 PPPVIK------------PQTSAVEQERWDEDSFYGLWDTNDEQGLN----SEFKSETAA 1601
P I+ P + R DED DT GL S + +T
Sbjct: 2272 PRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDG-EASEDTPQVPGLGSGGFSRVRMKTPT 2330
Query: 1602 IPSAPVLPPPPVHSSIPPPGPVPMGMP----PMSKPPPV 1636
+ L P + PGP+ P P PP V
Sbjct: 2331 VRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQV 2369
Score = 39.7 bits (91), Expect = 0.032
Identities = 39/158 (24%), Positives = 53/158 (33%), Gaps = 34/158 (21%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVP---------------VTRPPVPIPPPPP 1551
PPP PPPP PP + S P P +T PP+ P P
Sbjct: 619 PPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPE 678
Query: 1552 PPPLPPPPPVIKPQTSAVEQERW---------------DEDSFYGLWDTNDEQGLNSEFK 1596
P P P +P+ AV + E S +G ++ ++
Sbjct: 679 PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLL 738
Query: 1597 SETAAIPSA--PVLPPPPVHSSIPPPGPVPMGMPPMSK 1632
A+ + P PPP PPP P MPP+ K
Sbjct: 739 QPLQALQTQLLPQALPPPQPQLQPPPS--PQQMPPLEK 774
Score = 36.6 bits (83), Expect = 0.27
Identities = 23/57 (40%), Positives = 29/57 (50%), Gaps = 9/57 (15%)
Query: 1514 PPPPMGKPPGSIVRPSAPPARS--SVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSA 1568
P G+PPG RP+ P R +V V V IP P PPPP+ P +K QT +
Sbjct: 216 PRRSRGRPPG---RPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVP----VKHQTGS 265
Score = 35.8 bits (81), Expect = 0.46
Identities = 47/216 (21%), Positives = 73/216 (33%), Gaps = 36/216 (16%)
Query: 79 HHLPP---PPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135
HH+P P P PP P P+ P P P+ + P
Sbjct: 1896 HHIPTVGDPDFPAPPRR--------SRRPSPLAPRPPPS----------------RWASP 1931
Query: 136 PGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQP----SP 191
P +L PP + V + + P+ + PP P PS PP P + S
Sbjct: 1932 PLKTSPQLRVPPPTSVV---TALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSA 1988
Query: 192 SQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPP--P 249
+ + S L P ++ SH S + S H +++ P
Sbjct: 1989 ADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLA 2048
Query: 250 PSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDP 285
PSA PG Q + ++ G +++ QQ + P
Sbjct: 2049 PSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTP 2084
Score = 35.4 bits (80), Expect = 0.61
Identities = 41/155 (26%), Positives = 54/155 (34%), Gaps = 40/155 (25%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSV-PVTRPPVPIP- 1547
P + S +QN P + P GS PP P I P+ P+R + V+ P+P P
Sbjct: 1832 PERHSPIQNLD--PPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPG 1889
Query: 1548 -----------------PPPP-----PPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDT 1585
P PP P PL P PP RW T
Sbjct: 1890 SPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPP----------PSRWASPPL----KT 1935
Query: 1586 NDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP 1620
+ + + TA P++ L PP S PPP
Sbjct: 1936 SPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970
Score = 34.7 bits (78), Expect = 1.0
Identities = 38/122 (31%), Positives = 46/122 (37%), Gaps = 24/122 (19%)
Query: 1086 PGSSREKVPGGLQGSQDRGAAGSRERGPPR-----RAGSQERGP-----------LRRAG 1129
PGS+R + PG +G+ G G R G R R G GP LR G
Sbjct: 13 PGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAEPGEDTALLRLLG 72
Query: 1130 SRERIPPRRAGSRERGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGG----EKMYPYHR 1185
R + R R PR R RG GR +G RG E G E+ +H
Sbjct: 73 LRRGL---RRLRRLWAGPRVQRGRGRGRGRG-WGPSRGCVPEEESSDGESDEEEFQGFHS 128
Query: 1186 DE 1187
DE
Sbjct: 129 DE 130
Score = 33.9 bits (76), Expect = 1.8
Identities = 23/93 (24%), Positives = 36/93 (38%), Gaps = 18/93 (19%)
Query: 289 TPQEQQQYWYRQHLLSL----------------QQRTKVHLPGHKKGPVVAKDTPEPVKE 332
T +++ WYR +L + +T VH P P +D P +
Sbjct: 1767 TVDARRRCWYRCRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPP--LDT 1824
Query: 333 EVTVPATSQVPESPSSEEPPLPPPNEEVPPPLP 365
+V VP + + +PPL P + PPP P
Sbjct: 1825 DVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAP 1857
Score = 33.5 bits (75), Expect = 2.3
Identities = 30/131 (22%), Positives = 50/131 (38%), Gaps = 16/131 (12%)
Query: 246 APPPPSAPPGNKTT-VQQEPLESGAKNKSTEQQQAAP--EPDPSTMTPQEQQQYWYRQHL 302
+P P S PPG + + + L GA + + Q P PD + P + + +
Sbjct: 1807 SPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIK 1866
Query: 303 LSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP--PLPPPNEEV 360
+ ++ L G GP+ + +P + + P+ +P P PP
Sbjct: 1867 VPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI-----------PTVGDPDFPAPPRRSRR 1915
Query: 361 PPPLPPEEPQS 371
P PL P P S
Sbjct: 1916 PSPLAPRPPPS 1926
Score = 33.1 bits (74), Expect = 3.0
Identities = 31/130 (23%), Positives = 40/130 (30%), Gaps = 47/130 (36%)
Query: 1533 ARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLN 1592
ARSS + P + PP PP PV++P + +
Sbjct: 534 ARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITT-----------------------S 570
Query: 1593 SEFKSETAAIPSAPVLPPPP-----------------------VHSSIPPPGPVPMGMPP 1629
E A +PS P P PP + +PPP P P PP
Sbjct: 571 PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAP-PPPP 629
Query: 1630 MSKPPPVQQT 1639
PPP T
Sbjct: 630 APSPPPAPAT 639
Score = 32.7 bits (73), Expect = 3.9
Identities = 29/101 (28%), Positives = 37/101 (36%), Gaps = 6/101 (5%)
Query: 511 MGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLP 570
+G +S P +P P L P V P P P P+ + P P P L
Sbjct: 1877 LGGVSFGP--LPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLK 1934
Query: 571 TS----VPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPP 607
TS VPPP + + + PP S PP L P
Sbjct: 1935 TSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
Score = 31.6 bits (70), Expect = 8.8
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 3/74 (4%)
Query: 1755 SSRRGGFDRPSYDRKSDRPVYEGPSMFGGERRTYPEERMPLPAP---SLSHQPPPAPRVE 1811
S+RR RPSYD D E RRT E +PLP P S +P P ++
Sbjct: 1075 SARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQ 1134
Query: 1812 KKPESKNVDDILKP 1825
K + D L P
Sbjct: 1135 LKARRRLDKDALAP 1148
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 95.5 bits (236), Expect = 5e-19
Identities = 103/376 (27%), Positives = 137/376 (36%), Gaps = 59/376 (15%)
Query: 522 PYSQMPPPLPTMPPPV---LPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGM 578
P S +P PLP PP+ P ++PPP +PP P + PP P P +PPPG
Sbjct: 639 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTP--PLGIPPPGF 696
Query: 579 PPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGV 638
P + PPP PPP L P LPP L PPP+ TPP IPPP
Sbjct: 697 GPGV----PPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI---------TPPVSIPPPHT 743
Query: 639 PQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQV 698
P P T A + ++ +S G+ PT +A + V
Sbjct: 744 PPISIPNSTIAGINEDTTKD----------------LSIGNPIPTVVSGARGNAESGDSV 787
Query: 699 ----NSKAPLSKSALPYSSFSSDQGL-GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSY 753
++ P + + LP + L G AP I + S GLL P
Sbjct: 788 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI----GLQAPSTGLLGARPGLIP 843
Query: 754 LESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIP 813
L+ P G +RF + PRP P P + P G K + P
Sbjct: 844 LQRPPGMPPPHLQRFPLMP-----PRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFP--P 896
Query: 814 RGPASQFYITPSTSLSPRQSGPQWKGPKPAFG-----QQHQQQPKSQAEPLSGNKEPLAD 868
GP ++ P GP GP+ G QQ QQQP+ QA ++
Sbjct: 897 HGP----FVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQP 952
Query: 869 TSSNQQKNFKMQSAAF 884
S Q + Q F
Sbjct: 953 PPSQQPPPTQQQPQQF 968
Score = 90.5 bits (223), Expect = 2e-17
Identities = 113/380 (29%), Positives = 146/380 (38%), Gaps = 77/380 (20%)
Query: 532 TMPPPVLPPSLPPPVMPPALPA--TVPPPGMP-----PPVM----PPSL--PTSVPPPGM 578
T P +P LP PV P +PA TVPPP +P PPV+ PP+ P +PPPG
Sbjct: 637 TEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGF 696
Query: 579 PPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGV 638
P + PPP PPP L P LPP L PPP+ PP+S PPP PP +
Sbjct: 697 GPGV----PPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI--TPPVS--IPPPHTPPISI 748
Query: 639 PQ----GIPPQLT-----AAPVPP--------ASSSQSSQVPEKPRPALLPTPVSFGSAP 681
P GI T P+P A S S ++ P PT + P
Sbjct: 749 PNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNL---PTP 805
Query: 682 PTTYHPPL---QSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMP 738
P T L Q P + +AP + + GL P P ++ P
Sbjct: 806 PVTQPVSLLGTQGVAPGPVIGLQAPST------GLLGARPGLIPLQRPPGMPPPHLQRFP 859
Query: 739 VRSGGLLPDPPRSSYLESPRGP-RFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRY 797
+ P PP + P GP F P +GP P P GP R
Sbjct: 860 LMPP--RPMPPHMMHRGPPPGPGGFAMPP-----PHGMKGPFP---------PHGPFVRP 903
Query: 798 EGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPR--QSGPQWKGPKPAFGQQHQQQPKSQ 855
G P G G P GP + P+ Q PQ + P+ QQ QQ P SQ
Sbjct: 904 GGMPGLGGP---GPGPGGPEDR----DGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQ 956
Query: 856 AEPLSGNKEPLADTSSNQQK 875
+P ++P + N+Q+
Sbjct: 957 -QPPPTQQQPQQFRNDNRQQ 975
Score = 65.1 bits (157), Expect = 7e-10
Identities = 83/319 (26%), Positives = 113/319 (35%), Gaps = 70/319 (21%)
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPP-SLPPPVMPP-ALP-ATVP----------PPGM 560
M +PP F+P P PPP+ PP S+PPP PP ++P +T+ G
Sbjct: 717 MHLPPGFLP--------PGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGN 768
Query: 561 PPP---------------------VMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSA 599
P P +PP+ PT++P P + +S G V P P +
Sbjct: 769 PIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQ 828
Query: 600 GPPPVL--PPPSLSSTAPPPVMPLPPLS--SATPPPGIPPPGVPQGIPPQLTAAPVPPAS 655
P L P L PP MP P L PP +PP + +G PP +PP
Sbjct: 829 APSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPH 888
Query: 656 SSQSSQVPEKP--RPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSS 713
+ P P RP +P G P GP ++ + P P
Sbjct: 889 GMKGPFPPHGPFVRPGGMPGLGGPGPGP----------GGPEDRDGRQQP------PQQP 932
Query: 714 FSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGS 773
Q AP QP + P S P + + +F+ R E G
Sbjct: 933 QQQPQ-----PQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGR 987
Query: 774 RCEGPRPKGPRFE-GNRPD 791
R G R + R GNR D
Sbjct: 988 RSFGNRVENDRERYGNRND 1006
Score = 60.1 bits (144), Expect = 2e-08
Identities = 95/391 (24%), Positives = 129/391 (32%), Gaps = 98/391 (25%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
P P+P P PV +P P P + P P HQ
Sbjct: 639 PVSPIPKPLPVPVPPI-PVPAPITVPPPQVPP---------------------HQPGPPV 676
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134
V L PP PP +P G+G PPPPP PP L
Sbjct: 677 V---GALQPPAFTPPLGIPPPGFGPGVPPPPPPPP-----------------FLR----- 711
Query: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTS-------SQPYLPPA 187
PG PM L P PP PP PP +PPP PP P ++ + L
Sbjct: 712 -PGFNPMHL-PPGFLPPGPPPPITPPVS--IPPPHTPPISIPNSTIAGINEDTTKDLSIG 767
Query: 188 QPSP--------------------SQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPS 227
P P S PP+ PTP + S L +Q P
Sbjct: 768 NPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVS-----LLGTQGVAPG 822
Query: 228 SQASPSRPSQGHSKSQLLAPP---PPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD 284
PS G ++ P PP PP + +Q+ PL + P P
Sbjct: 823 PVIGLQAPSTGLLGARPGLIPLQRPPGMPPPH---LQRFPL-MPPRPMPPHMMHRGPPPG 878
Query: 285 PS--TMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKD---TPEPVKEEVTVPAT 339
P M P + + H ++ L G GP +D +P ++ P
Sbjct: 879 PGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQP-Q 937
Query: 340 SQVPESPSSEEPPLPPPNEEVPPPLPPEEPQ 370
Q P+ P ++ PPP+++ PP ++PQ
Sbjct: 938 PQAPQQPQQQQQQQPPPSQQPPP--TQQQPQ 966
Score = 57.4 bits (137), Expect = 1e-07
Identities = 72/270 (26%), Positives = 100/270 (37%), Gaps = 42/270 (15%)
Query: 1501 SRPGMYP---PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP--PL 1555
+RPG+ P PPG PPP + + P RP P P P PPP P
Sbjct: 837 ARPGLIPLQRPPGM--PPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPF 894
Query: 1556 PPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHS 1615
PP P ++P GL G E + P P P P +
Sbjct: 895 PPHGPFVRP------------GGMPGLGGPGPGPG-GPEDRDGRQQPPQQPQQQPQP-QA 940
Query: 1616 SIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTF 1675
P PP +PPP QQ + + +Q G ++ F
Sbjct: 941 PQQPQQQQQQQPPPSQQPPPTQQ-----QPQQFRNDNRQQFNSGR----------DQERF 985
Query: 1676 ETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKR---DRETHRD-RDRDRGVIDY-DR 1730
G R DRER DR N D R++ R DR+ HRD +R+R + DR
Sbjct: 986 GRRSFGNRVENDRERYGNRNDDR-DNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDR 1044
Query: 1731 DRFDRERRPRDDRAQSYRDKKDHSSSRRGG 1760
+R R+R R ++ ++ +K + R GG
Sbjct: 1045 ERDSRDRESRREKEEARGKEKPEVTDRAGG 1074
Score = 56.6 bits (135), Expect = 3e-07
Identities = 83/372 (22%), Positives = 122/372 (32%), Gaps = 55/372 (14%)
Query: 45 PSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPL--PPPPVMPGGGYGDWQP 102
P G E +AQ + H + + + +P +P PP+ P P +P QP
Sbjct: 613 PDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQP 672
Query: 103 PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ 162
PP + PA + PP +P P PP PP ++ P
Sbjct: 673 GPPVVGALQPPAFT------------------PPLGIPPPGFGPGVPPPPPPPPFLRPG- 713
Query: 163 SYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQ 222
P PP + PP P PP P +PP P + + + + LS
Sbjct: 714 --FNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPIS---IPNSTIAGINEDTTKDLSIGN 768
Query: 223 SYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPE 282
+ G S + PP+AP T +P+ Q AP
Sbjct: 769 PIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPV------SLLGTQGVAPG 822
Query: 283 PDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQV 342
P P R L+ LQ+ + P ++ P++ P P+ +
Sbjct: 823 PVIGLQAP-STGLLGARPGLIPLQRPPGMPPPHLQRFPLM---PPRPMPPHMMHRGPPPG 878
Query: 343 P-----ESPSSEEPPLPPPNEEVPP--------PLP-PEEPQSED-----PEEDARLKQL 383
P P + P PP V P P P P P+ D P++ + Q
Sbjct: 879 PGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQP 938
Query: 384 QAAAAHWQQHQQ 395
QA QQ QQ
Sbjct: 939 QAPQQPQQQQQQ 950
Score = 49.3 bits (116), Expect = 4e-05
Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 1/131 (0%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75
P PP P A A+ P +S P AP ++ Q Q + Q + M
Sbjct: 275 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQ 334
Query: 76 LQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135
P H PLPP MPG G P PP P P Q+ Q Q +
Sbjct: 335 QDPMH-HQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 393
Query: 136 PGLVPMELESP 146
P ME+E P
Sbjct: 394 PHQQEMEVEQP 404
Score = 47.4 bits (111), Expect = 2e-04
Identities = 56/194 (28%), Positives = 70/194 (36%), Gaps = 39/194 (20%)
Query: 1483 PQMADHLP--PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVT 1540
PQ+ H P P LQ + P + PP + P P PP +RP P P
Sbjct: 665 PQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLP-PGF 723
Query: 1541 RPPVPIPPPPPPPPL-PP--PPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKS 1597
PP P PP PP + PP PP I T A E +D G G +S
Sbjct: 724 LPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAES 783
Query: 1598 -------ETAAIPSAPV-LPPPPVHSSIP-------PPGPV------------------P 1624
+A P+AP LP PPV + PGPV P
Sbjct: 784 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 843
Query: 1625 MGMPPMSKPPPVQQ 1638
+ PP PP +Q+
Sbjct: 844 LQRPPGMPPPHLQR 857
Score = 47.0 bits (110), Expect = 2e-04
Identities = 76/299 (25%), Positives = 104/299 (34%), Gaps = 54/299 (18%)
Query: 329 PVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAA 388
PV E VT S P S EPP + P P PQ P DA AA A
Sbjct: 128 PVAENVTNNEGSPPPPVKVSSEPP-----TQATPNSVPAVPQL--PSSDA-----FAAVA 175
Query: 389 HWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQF 448
Q Q + QLQQILQ +QQ PP Q+ ++D + Q
Sbjct: 176 QLFQTTQGQ-------------QLQQILQTFQQ----PPKPQSPALDNAV------MAQV 212
Query: 449 QHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWK---TWQGHMKATQSYLQEKVNSFQN 505
Q + + + EQ ++P +Q ++K+ + +A + +E +
Sbjct: 213 QAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAV-- 270
Query: 506 MKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVM 565
+ P VP P P T+P P + PP PP P P GM P
Sbjct: 271 -------TTTAPAAAVP----PAPTATVPAAAAPAAASPP--PPQAPFGFPGDGMQQPAY 317
Query: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPL 624
P M V PP+ G +LP P A P + P PP+
Sbjct: 318 TQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPG-FGLLPTPPFPPMAQPVIPPTPPV 375
Score = 47.0 bits (110), Expect = 2e-04
Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 58/172 (33%)
Query: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP-PGSIVRPSAPPARSS 1536
D+ P+ ++ Q + + + P P P PP+ P P ++ P PP +
Sbjct: 614 DWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPG 673
Query: 1537 VPVT--------RPPVPIPPPP-----PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
PV PP+ IPPP PPP PPPPP ++P
Sbjct: 674 PPVVGALQPPAFTPPLGIPPPGFGPGVPPP--PPPPPFLRP------------------- 712
Query: 1584 DTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
G N P+ PP PPGP P PP+S PPP
Sbjct: 713 ------GFN-------------PMHLPP----GFLPPGPPPPITPPVSIPPP 741
Score = 46.6 bits (109), Expect = 3e-04
Identities = 60/260 (23%), Positives = 85/260 (32%), Gaps = 60/260 (23%)
Query: 15 PPPPVPPP--------PPVALPEASPGPGYSSSTT-------PAAPSSSGFMSFREQHLA 59
PPPP+ PP PP+++P ++ G + TT P SG + A
Sbjct: 728 PPPPITPPVSIPPPHTPPISIPNSTIA-GINEDTTKDLSIGNPIPTVVSG-----ARGNA 781
Query: 60 QLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQK 119
+ +M+ + P +LP PP+ P + G PGP + Q
Sbjct: 782 ESGDSVKMYGSAVPPAA-PTNLPTPPVTQPVSLLG-----------TQGVAPGPVIGLQA 829
Query: 120 QQQ----YKHQMLHHQRDGPPGLVPMELESPPESPPVP-------------PGSYMPPSQ 162
+ ++ QR PPG+ P L+ P PP P PG + P
Sbjct: 830 PSTGLLGARPGLIPLQR--PPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPP 887
Query: 163 SYMPPPQPPPSYYPPTSSQPYLPPAQPSPS--------QSPPSQSYLAPTPSYSSSSSSS 214
M P PP + P L P P Q PP Q P P
Sbjct: 888 HGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQ 947
Query: 215 QSYLSHSQSYLPSSQASPSR 234
Q P +Q P +
Sbjct: 948 QQQQPPPSQQPPPTQQQPQQ 967
Score = 43.9 bits (102), Expect = 0.002
Identities = 65/286 (22%), Positives = 92/286 (32%), Gaps = 44/286 (15%)
Query: 15 PPPPVP---PPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71
PPPPV PP A P + P P PSS F + +AQL Q Q +Q
Sbjct: 140 PPPPVKVSSEPPTQATPNSVPA-------VPQLPSSDAFAA-----VAQLFQTTQ--GQQ 185
Query: 72 MQCVLQPHHLPPPPLPPPPVMPGGGYGDWQ------PPPPPMP-------PPPGPALSYQ 118
+Q +LQ PP P P + Q P P PPP ++
Sbjct: 186 LQQILQTFQ--QPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFD 243
Query: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178
K+ + D P + + E P + +PP+ + P P+ P
Sbjct: 244 KKLLDRFD----YDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASP- 298
Query: 179 SSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS----- 233
P P P P+ + + Q H Q LP + P
Sbjct: 299 -PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLP 357
Query: 234 RPSQGHSKSQLLAPPPPSAPPGNKT-TVQQEPLESGAKNKSTEQQQ 278
P ++ P PP P + Q EPL + E +Q
Sbjct: 358 TPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQ 403
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/301 (20%), Positives = 104/301 (34%), Gaps = 89/301 (29%)
Query: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT--------------------P 205
PPP S PPT + P PA P Q P S ++ A P
Sbjct: 140 PPPPVKVSSEPPTQATPNSVPAVP---QLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 196
Query: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQ--- 262
S + + ++ Q+ + +P++PS+ + PPP +K + +
Sbjct: 197 PKPQSPALDNAVMAQVQAITAQLKTTPTQPSE----QKAAFPPPEQKTAFDKKLLDRFDY 252
Query: 263 ----EPLESGAKNKSTEQQQAAPE----PDPSTMTP-----------------------Q 291
E +E K +T AP P P+ P
Sbjct: 253 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 312
Query: 292 EQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP 351
+Q Y Q++ Q R + G ++ +P+ +V +P Q+P P
Sbjct: 313 QQPAYTQHQNMDQFQPR----MMGIQQ---------DPMHHQVPLPPNGQMPGFGLLPTP 359
Query: 352 PLPPPNEEVPPPLPP------------EEPQSEDP-EEDARLKQ--LQAAAAHWQQHQQH 396
P PP + V PP PP EP ++ P +++ ++Q +Q H +++
Sbjct: 360 PFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKS 419
Query: 397 R 397
R
Sbjct: 420 R 420
Score = 43.1 bits (100), Expect = 0.003
Identities = 38/164 (23%), Positives = 59/164 (35%), Gaps = 14/164 (8%)
Query: 82 PPPPLPPPPV--MPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLV 139
P +PP P +P PPPP P P Q+ +HQ + + P ++
Sbjct: 275 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQ---PRMM 331
Query: 140 PMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQS 199
++ + P+PP MP PP PP +QP +PP P Q P S
Sbjct: 332 GIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPP-------MAQPVIPPT--PPVQQPFQAS 382
Query: 200 YLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243
+ A + + + S +R S+ S S+
Sbjct: 383 FQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR 426
Score = 42.0 bits (97), Expect = 0.006
Identities = 53/226 (23%), Positives = 82/226 (36%), Gaps = 39/226 (17%)
Query: 1529 SAPPA-RSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTND 1587
+ PPA ++VP P PPPP P P ++ Q + + + D+
Sbjct: 278 AVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQ-QPAYTQHQNMDQ----------- 325
Query: 1588 EQGLNSEFKSETAAIPSAPV-----LPPP---PVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639
F+ I P+ LPP P +P P PM P + PPVQQ
Sbjct: 326 -------FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQ- 377
Query: 1640 VDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRY-----DRERDREP 1694
+ + Q P+ + + + + E +++ R R R R R
Sbjct: 378 -PFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSG 436
Query: 1695 YFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740
R+S R R R+ R R R DR++ +RERR +
Sbjct: 437 SRSRRSR---HRRSRSRSRDRRRHSPRSRSQERRDREK-ERERRQK 478
Score = 37.4 bits (85), Expect = 0.16
Identities = 74/350 (21%), Positives = 113/350 (32%), Gaps = 81/350 (23%)
Query: 1497 QNTSSRPGMYPPPGSYRPPPPMGKPPGSIVR-PSAPPARSSVPVTR-------------- 1541
+N ++ G PPP PP P S+ P P + + V +
Sbjct: 131 ENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQIL 190
Query: 1542 PPVPIPPPPPPPPL------------------PPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
PP P P L P P K EQ+ + +
Sbjct: 191 QTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRF 250
Query: 1584 DTNDEQGLNSEFKSE--TAAIPSAPVLPPPPVHSSI-----------PPPGPVPMGMP-- 1628
D +DE E K E TA +AP PP ++ PPP P G P
Sbjct: 251 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGD 310
Query: 1629 PMSKPPPVQ-QTVDYGHGRDISTNKVEQIPYGERITLRPD---------------PL--- 1669
M +P Q Q +D R + ++Q P ++ L P+ P+
Sbjct: 311 GMQQPAYTQHQNMDQFQPRMMG---IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQP 367
Query: 1670 ------PERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDR 1723
P + F+ Q + ++ + + + I + + D R R R
Sbjct: 368 VIPPTPPVQQPFQASFQAQNEPL-TQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR 426
Query: 1724 GVIDYDRDRFDRERRPRDDRAQS-YRDKKDHSSSRRGGFDRPSYDRKSDR 1772
R RR R R++S RD++ HS R R DR+ +R
Sbjct: 427 SPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERR---DREKER 473
Score = 35.8 bits (81), Expect = 0.46
Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 29/209 (13%)
Query: 1171 PEPGDGGEKMYPYHRDE---PPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYW 1227
P PG GG M P H + PP P+ P G P +R+ R++
Sbjct: 875 PPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRD-----GRQQPP 929
Query: 1228 RECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMD 1287
++ ++ Q + ++ + PPS+ ++ P Q D NR+ + +
Sbjct: 930 QQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP--------QQFRND-NRQ-QFNSG 979
Query: 1288 RDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYR 1347
RD +R R + ++N+ +R YG D++++ R+R P DR+R
Sbjct: 980 RDQERFGR--RSFGNRVENDRER-YGNRNDDRDNSNRDRREWGRRS-------PDRDRHR 1029
Query: 1348 DDRWREERNREH-GYDRDFRDRGELRIRE 1375
D R R+ H +RD RDR R +E
Sbjct: 1030 DLEERNRRSSGHRDRERDSRDRESRREKE 1058
Score = 33.9 bits (76), Expect = 1.8
Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 46/201 (22%)
Query: 1134 IPPRRAGSR--ERGPPRGPGSRERGLGRSDFGRDRGPFRPE---------PGDGGEKMYP 1182
+PPR RGPP GPG G +GPF P PG GG P
Sbjct: 861 MPPRPMPPHMMHRGPPPGPG----GFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGP 916
Query: 1183 ------YHRDEPPRAPWNHGE-------ERGHEEFPLDGRNAPMERERLDDW-------- 1221
R +PP+ P + ++ ++ P + P +++ +
Sbjct: 917 GGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQF 976
Query: 1222 ----DRERYWRECERDYQDDTLELY-NREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDE 1276
D+ER+ R + ++ E Y NR D + RR P D +R +D++E
Sbjct: 977 NSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSP---DRDRHRDLEE 1033
Query: 1277 DYNREM-ERDMDRDV-DRISR 1295
R RD +RD DR SR
Sbjct: 1034 RNRRSSGHRDRERDSRDRESR 1054
Score = 33.5 bits (75), Expect = 2.3
Identities = 31/130 (23%), Positives = 47/130 (36%), Gaps = 45/130 (34%)
Query: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPP-----------PGSYRPPPPM---GKPPG 1523
D+ EP+ + +++ T++ PP P + PPPP G P
Sbjct: 251 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGD 310
Query: 1524 SIVRPS------------------APPARSSVPVTRPP---------VPIPPPPP--PPP 1554
+ +P+ P VP+ PP +P PP PP P
Sbjct: 311 GMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPL--PPNGQMPGFGLLPTPPFPPMAQPV 368
Query: 1555 LPPPPPVIKP 1564
+PP PPV +P
Sbjct: 369 IPPTPPVQQP 378
Score = 32.7 bits (73), Expect = 3.9
Identities = 28/90 (31%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPP----VMPP 567
G +MPPP M P P P V P + P L P PG P PP
Sbjct: 880 GGFAMPPP----HGMKGPFPPHGPFVRPGGM------PGLGGPGPGPGGPEDRDGRQQPP 929
Query: 568 SLPTSVP---PPGMPPSLSSAGPPPVLPPP 594
P P P P PPP PP
Sbjct: 930 QQPQQQPQPQAPQQPQQQQQQQPPPSQQPP 959
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 95.5 bits (236), Expect = 5e-19
Identities = 103/376 (27%), Positives = 137/376 (36%), Gaps = 59/376 (15%)
Query: 522 PYSQMPPPLPTMPPPV---LPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGM 578
P S +P PLP PP+ P ++PPP +PP P + PP P P +PPPG
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTP--PLGIPPPGF 711
Query: 579 PPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGV 638
P + PPP PPP L P LPP L PPP+ TPP IPPP
Sbjct: 712 GPGV----PPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI---------TPPVSIPPPHT 758
Query: 639 PQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQV 698
P P T A + ++ +S G+ PT +A + V
Sbjct: 759 PPISIPNSTIAGINEDTTKD----------------LSIGNPIPTVVSGARGNAESGDSV 802
Query: 699 ----NSKAPLSKSALPYSSFSSDQGL-GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSY 753
++ P + + LP + L G AP I + S GLL P
Sbjct: 803 KMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVI----GLQAPSTGLLGARPGLIP 858
Query: 754 LESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIP 813
L+ P G +RF + PRP P P + P G K + P
Sbjct: 859 LQRPPGMPPPHLQRFPLMP-----PRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFP--P 911
Query: 814 RGPASQFYITPSTSLSPRQSGPQWKGPKPAFG-----QQHQQQPKSQAEPLSGNKEPLAD 868
GP ++ P GP GP+ G QQ QQQP+ QA ++
Sbjct: 912 HGP----FVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQP 967
Query: 869 TSSNQQKNFKMQSAAF 884
S Q + Q F
Sbjct: 968 PPSQQPPPTQQQPQQF 983
Score = 90.5 bits (223), Expect = 2e-17
Identities = 113/380 (29%), Positives = 146/380 (38%), Gaps = 77/380 (20%)
Query: 532 TMPPPVLPPSLPPPVMPPALPA--TVPPPGMP-----PPVM----PPSL--PTSVPPPGM 578
T P +P LP PV P +PA TVPPP +P PPV+ PP+ P +PPPG
Sbjct: 652 TEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGF 711
Query: 579 PPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGV 638
P + PPP PPP L P LPP L PPP+ PP+S PPP PP +
Sbjct: 712 GPGV----PPPPPPPPFLRPGFNPMHLPPGFLPPGPPPPI--TPPVS--IPPPHTPPISI 763
Query: 639 PQ----GIPPQLT-----AAPVPP--------ASSSQSSQVPEKPRPALLPTPVSFGSAP 681
P GI T P+P A S S ++ P PT + P
Sbjct: 764 PNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNL---PTP 820
Query: 682 PTTYHPPL---QSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMP 738
P T L Q P + +AP + + GL P P ++ P
Sbjct: 821 PVTQPVSLLGTQGVAPGPVIGLQAPST------GLLGARPGLIPLQRPPGMPPPHLQRFP 874
Query: 739 VRSGGLLPDPPRSSYLESPRGP-RFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRY 797
+ P PP + P GP F P +GP P P GP R
Sbjct: 875 LMPP--RPMPPHMMHRGPPPGPGGFAMPP-----PHGMKGPFP---------PHGPFVRP 918
Query: 798 EGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPR--QSGPQWKGPKPAFGQQHQQQPKSQ 855
G P G G P GP + P+ Q PQ + P+ QQ QQ P SQ
Sbjct: 919 GGMPGLGGP---GPGPGGPEDR----DGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQ 971
Query: 856 AEPLSGNKEPLADTSSNQQK 875
+P ++P + N+Q+
Sbjct: 972 -QPPPTQQQPQQFRNDNRQQ 990
Score = 65.1 bits (157), Expect = 7e-10
Identities = 83/319 (26%), Positives = 113/319 (35%), Gaps = 70/319 (21%)
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPP-SLPPPVMPP-ALP-ATVP----------PPGM 560
M +PP F+P P PPP+ PP S+PPP PP ++P +T+ G
Sbjct: 732 MHLPPGFLP--------PGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGN 783
Query: 561 PPP---------------------VMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSA 599
P P +PP+ PT++P P + +S G V P P +
Sbjct: 784 PIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQ 843
Query: 600 GPPPVL--PPPSLSSTAPPPVMPLPPLS--SATPPPGIPPPGVPQGIPPQLTAAPVPPAS 655
P L P L PP MP P L PP +PP + +G PP +PP
Sbjct: 844 APSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPH 903
Query: 656 SSQSSQVPEKP--RPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSS 713
+ P P RP +P G P GP ++ + P P
Sbjct: 904 GMKGPFPPHGPFVRPGGMPGLGGPGPGP----------GGPEDRDGRQQP------PQQP 947
Query: 714 FSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGS 773
Q AP QP + P S P + + +F+ R E G
Sbjct: 948 QQQPQ-----PQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGR 1002
Query: 774 RCEGPRPKGPRFE-GNRPD 791
R G R + R GNR D
Sbjct: 1003 RSFGNRVENDRERYGNRND 1021
Score = 60.1 bits (144), Expect = 2e-08
Identities = 95/391 (24%), Positives = 129/391 (32%), Gaps = 98/391 (25%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
P P+P P PV +P P P + P P HQ
Sbjct: 654 PVSPIPKPLPVPVPPI-PVPAPITVPPPQVPP---------------------HQPGPPV 691
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134
V L PP PP +P G+G PPPPP PP L
Sbjct: 692 V---GALQPPAFTPPLGIPPPGFGPGVPPPPPPPP-----------------FLR----- 726
Query: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTS-------SQPYLPPA 187
PG PM L P PP PP PP +PPP PP P ++ + L
Sbjct: 727 -PGFNPMHL-PPGFLPPGPPPPITPPVS--IPPPHTPPISIPNSTIAGINEDTTKDLSIG 782
Query: 188 QPSP--------------------SQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPS 227
P P S PP+ PTP + S L +Q P
Sbjct: 783 NPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPVS-----LLGTQGVAPG 837
Query: 228 SQASPSRPSQGHSKSQLLAPP---PPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPD 284
PS G ++ P PP PP + +Q+ PL + P P
Sbjct: 838 PVIGLQAPSTGLLGARPGLIPLQRPPGMPPPH---LQRFPL-MPPRPMPPHMMHRGPPPG 893
Query: 285 PS--TMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKD---TPEPVKEEVTVPAT 339
P M P + + H ++ L G GP +D +P ++ P
Sbjct: 894 PGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQP-Q 952
Query: 340 SQVPESPSSEEPPLPPPNEEVPPPLPPEEPQ 370
Q P+ P ++ PPP+++ PP ++PQ
Sbjct: 953 PQAPQQPQQQQQQQPPPSQQPPP--TQQQPQ 981
Score = 57.4 bits (137), Expect = 1e-07
Identities = 72/270 (26%), Positives = 100/270 (37%), Gaps = 42/270 (15%)
Query: 1501 SRPGMYP---PPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP--PL 1555
+RPG+ P PPG PPP + + P RP P P P PPP P
Sbjct: 852 ARPGLIPLQRPPGM--PPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPF 909
Query: 1556 PPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHS 1615
PP P ++P GL G E + P P P P +
Sbjct: 910 PPHGPFVRP------------GGMPGLGGPGPGPG-GPEDRDGRQQPPQQPQQQPQP-QA 955
Query: 1616 SIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTF 1675
P PP +PPP QQ + + +Q G ++ F
Sbjct: 956 PQQPQQQQQQQPPPSQQPPPTQQ-----QPQQFRNDNRQQFNSGR----------DQERF 1000
Query: 1676 ETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKR---DRETHRD-RDRDRGVIDY-DR 1730
G R DRER DR N D R++ R DR+ HRD +R+R + DR
Sbjct: 1001 GRRSFGNRVENDRERYGNRNDDR-DNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDR 1059
Query: 1731 DRFDRERRPRDDRAQSYRDKKDHSSSRRGG 1760
+R R+R R ++ ++ +K + R GG
Sbjct: 1060 ERDSRDRESRREKEEARGKEKPEVTDRAGG 1089
Score = 56.6 bits (135), Expect = 3e-07
Identities = 83/372 (22%), Positives = 122/372 (32%), Gaps = 55/372 (14%)
Query: 45 PSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPL--PPPPVMPGGGYGDWQP 102
P G E +AQ + H + + + +P +P PP+ P P +P QP
Sbjct: 628 PDWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQP 687
Query: 103 PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ 162
PP + PA + PP +P P PP PP ++ P
Sbjct: 688 GPPVVGALQPPAFT------------------PPLGIPPPGFGPGVPPPPPPPPFLRPG- 728
Query: 163 SYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQ 222
P PP + PP P PP P +PP P + + + + LS
Sbjct: 729 --FNPMHLPPGFLPPGPPPPITPPVSIPPPHTPPIS---IPNSTIAGINEDTTKDLSIGN 783
Query: 223 SYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPE 282
+ G S + PP+AP T +P+ Q AP
Sbjct: 784 PIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQPV------SLLGTQGVAPG 837
Query: 283 PDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQV 342
P P R L+ LQ+ + P ++ P++ P P+ +
Sbjct: 838 PVIGLQAP-STGLLGARPGLIPLQRPPGMPPPHLQRFPLM---PPRPMPPHMMHRGPPPG 893
Query: 343 P-----ESPSSEEPPLPPPNEEVPP--------PLP-PEEPQSED-----PEEDARLKQL 383
P P + P PP V P P P P P+ D P++ + Q
Sbjct: 894 PGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQP 953
Query: 384 QAAAAHWQQHQQ 395
QA QQ QQ
Sbjct: 954 QAPQQPQQQQQQ 965
Score = 49.3 bits (116), Expect = 4e-05
Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 1/131 (0%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75
P PP P A A+ P +S P AP ++ Q Q + Q + M
Sbjct: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQ 349
Query: 76 LQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135
P H PLPP MPG G P PP P P Q+ Q Q +
Sbjct: 350 QDPMH-HQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQK 408
Query: 136 PGLVPMELESP 146
P ME+E P
Sbjct: 409 PHQQEMEVEQP 419
Score = 47.4 bits (111), Expect = 2e-04
Identities = 56/194 (28%), Positives = 70/194 (36%), Gaps = 39/194 (20%)
Query: 1483 PQMADHLP--PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVT 1540
PQ+ H P P LQ + P + PP + P P PP +RP P P
Sbjct: 680 PQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLP-PGF 738
Query: 1541 RPPVPIPPPPPPPPL-PP--PPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKS 1597
PP P PP PP + PP PP I T A E +D G G +S
Sbjct: 739 LPPGPPPPITPPVSIPPPHTPPISIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGNAES 798
Query: 1598 -------ETAAIPSAPV-LPPPPVHSSIP-------PPGPV------------------P 1624
+A P+AP LP PPV + PGPV P
Sbjct: 799 GDSVKMYGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARPGLIP 858
Query: 1625 MGMPPMSKPPPVQQ 1638
+ PP PP +Q+
Sbjct: 859 LQRPPGMPPPHLQR 872
Score = 47.0 bits (110), Expect = 2e-04
Identities = 76/299 (25%), Positives = 104/299 (34%), Gaps = 54/299 (18%)
Query: 329 PVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAA 388
PV E VT S P S EPP + P P PQ P DA AA A
Sbjct: 143 PVAENVTNNEGSPPPPVKVSSEPP-----TQATPNSVPAVPQL--PSSDA-----FAAVA 190
Query: 389 HWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQF 448
Q Q + QLQQILQ +QQ PP Q+ ++D + Q
Sbjct: 191 QLFQTTQGQ-------------QLQQILQTFQQ----PPKPQSPALDNAV------MAQV 227
Query: 449 QHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWK---TWQGHMKATQSYLQEKVNSFQN 505
Q + + + EQ ++P +Q ++K+ + +A + +E +
Sbjct: 228 QAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAV-- 285
Query: 506 MKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVM 565
+ P VP P P T+P P + PP PP P P GM P
Sbjct: 286 -------TTTAPAAAVP----PAPTATVPAAAAPAAASPP--PPQAPFGFPGDGMQQPAY 332
Query: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPL 624
P M V PP+ G +LP P A P + P PP+
Sbjct: 333 TQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPG-FGLLPTPPFPPMAQPVIPPTPPV 390
Score = 47.0 bits (110), Expect = 2e-04
Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 58/172 (33%)
Query: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP-PGSIVRPSAPPARSS 1536
D+ P+ ++ Q + + + P P P PP+ P P ++ P PP +
Sbjct: 629 DWKGIPKKPENEVAQNGGAETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPG 688
Query: 1537 VPVT--------RPPVPIPPPP-----PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
PV PP+ IPPP PPP PPPPP ++P
Sbjct: 689 PPVVGALQPPAFTPPLGIPPPGFGPGVPPP--PPPPPFLRP------------------- 727
Query: 1584 DTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
G N P+ PP PPGP P PP+S PPP
Sbjct: 728 ------GFN-------------PMHLPP----GFLPPGPPPPITPPVSIPPP 756
Score = 46.6 bits (109), Expect = 3e-04
Identities = 60/260 (23%), Positives = 85/260 (32%), Gaps = 60/260 (23%)
Query: 15 PPPPVPPP--------PPVALPEASPGPGYSSSTT-------PAAPSSSGFMSFREQHLA 59
PPPP+ PP PP+++P ++ G + TT P SG + A
Sbjct: 743 PPPPITPPVSIPPPHTPPISIPNSTIA-GINEDTTKDLSIGNPIPTVVSG-----ARGNA 796
Query: 60 QLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQK 119
+ +M+ + P +LP PP+ P + G PGP + Q
Sbjct: 797 ESGDSVKMYGSAVPPAA-PTNLPTPPVTQPVSLLG-----------TQGVAPGPVIGLQA 844
Query: 120 QQQ----YKHQMLHHQRDGPPGLVPMELESPPESPPVP-------------PGSYMPPSQ 162
+ ++ QR PPG+ P L+ P PP P PG + P
Sbjct: 845 PSTGLLGARPGLIPLQR--PPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPP 902
Query: 163 SYMPPPQPPPSYYPPTSSQPYLPPAQPSPS--------QSPPSQSYLAPTPSYSSSSSSS 214
M P PP + P L P P Q PP Q P P
Sbjct: 903 HGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQ 962
Query: 215 QSYLSHSQSYLPSSQASPSR 234
Q P +Q P +
Sbjct: 963 QQQQPPPSQQPPPTQQQPQQ 982
Score = 43.9 bits (102), Expect = 0.002
Identities = 65/286 (22%), Positives = 92/286 (32%), Gaps = 44/286 (15%)
Query: 15 PPPPVP---PPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71
PPPPV PP A P + P P PSS F + +AQL Q Q +Q
Sbjct: 155 PPPPVKVSSEPPTQATPNSVPA-------VPQLPSSDAFAA-----VAQLFQTTQ--GQQ 200
Query: 72 MQCVLQPHHLPPPPLPPPPVMPGGGYGDWQ------PPPPPMP-------PPPGPALSYQ 118
+Q +LQ PP P P + Q P P PPP ++
Sbjct: 201 LQQILQTFQ--QPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFD 258
Query: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178
K+ + D P + + E P + +PP+ + P P+ P
Sbjct: 259 KKLLDRFD----YDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASP- 313
Query: 179 SSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS----- 233
P P P P+ + + Q H Q LP + P
Sbjct: 314 -PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLP 372
Query: 234 RPSQGHSKSQLLAPPPPSAPPGNKT-TVQQEPLESGAKNKSTEQQQ 278
P ++ P PP P + Q EPL + E +Q
Sbjct: 373 TPPFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQ 418
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/301 (20%), Positives = 104/301 (34%), Gaps = 89/301 (29%)
Query: 166 PPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT--------------------P 205
PPP S PPT + P PA P Q P S ++ A P
Sbjct: 155 PPPPVKVSSEPPTQATPNSVPAVP---QLPSSDAFAAVAQLFQTTQGQQLQQILQTFQQP 211
Query: 206 SYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQ--- 262
S + + ++ Q+ + +P++PS+ + PPP +K + +
Sbjct: 212 PKPQSPALDNAVMAQVQAITAQLKTTPTQPSE----QKAAFPPPEQKTAFDKKLLDRFDY 267
Query: 263 ----EPLESGAKNKSTEQQQAAPE----PDPSTMTP-----------------------Q 291
E +E K +T AP P P+ P
Sbjct: 268 DDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGM 327
Query: 292 EQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP 351
+Q Y Q++ Q R + G ++ +P+ +V +P Q+P P
Sbjct: 328 QQPAYTQHQNMDQFQPR----MMGIQQ---------DPMHHQVPLPPNGQMPGFGLLPTP 374
Query: 352 PLPPPNEEVPPPLPP------------EEPQSEDP-EEDARLKQ--LQAAAAHWQQHQQH 396
P PP + V PP PP EP ++ P +++ ++Q +Q H +++
Sbjct: 375 PFPPMAQPVIPPTPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKS 434
Query: 397 R 397
R
Sbjct: 435 R 435
Score = 43.1 bits (100), Expect = 0.003
Identities = 38/164 (23%), Positives = 59/164 (35%), Gaps = 14/164 (8%)
Query: 82 PPPPLPPPPV--MPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLV 139
P +PP P +P PPPP P P Q+ +HQ + + P ++
Sbjct: 290 PAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQ---PRMM 346
Query: 140 PMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQS 199
++ + P+PP MP PP PP +QP +PP P Q P S
Sbjct: 347 GIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPP-------MAQPVIPPT--PPVQQPFQAS 397
Query: 200 YLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQ 243
+ A + + + S +R S+ S S+
Sbjct: 398 FQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR 441
Score = 42.0 bits (97), Expect = 0.006
Identities = 53/226 (23%), Positives = 82/226 (36%), Gaps = 39/226 (17%)
Query: 1529 SAPPA-RSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTND 1587
+ PPA ++VP P PPPP P P ++ Q + + + D+
Sbjct: 293 AVPPAPTATVPAAAAPAAASPPPPQAPFGFPGDGMQ-QPAYTQHQNMDQ----------- 340
Query: 1588 EQGLNSEFKSETAAIPSAPV-----LPPP---PVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639
F+ I P+ LPP P +P P PM P + PPVQQ
Sbjct: 341 -------FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPPTPPVQQ- 392
Query: 1640 VDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRY-----DRERDREP 1694
+ + Q P+ + + + + E +++ R R R R R
Sbjct: 393 -PFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRRRSRSG 451
Query: 1695 YFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRERRPR 1740
R+S R R R+ R R R DR++ +RERR +
Sbjct: 452 SRSRRSR---HRRSRSRSRDRRRHSPRSRSQERRDREK-ERERRQK 493
Score = 37.4 bits (85), Expect = 0.16
Identities = 74/350 (21%), Positives = 113/350 (32%), Gaps = 81/350 (23%)
Query: 1497 QNTSSRPGMYPPPGSYRPPPPMGKPPGSIVR-PSAPPARSSVPVTR-------------- 1541
+N ++ G PPP PP P S+ P P + + V +
Sbjct: 146 ENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQQIL 205
Query: 1542 PPVPIPPPPPPPPL------------------PPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
PP P P L P P K EQ+ + +
Sbjct: 206 QTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLLDRF 265
Query: 1584 DTNDEQGLNSEFKSE--TAAIPSAPVLPPPPVHSSI-----------PPPGPVPMGMP-- 1628
D +DE E K E TA +AP PP ++ PPP P G P
Sbjct: 266 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGD 325
Query: 1629 PMSKPPPVQ-QTVDYGHGRDISTNKVEQIPYGERITLRPD---------------PL--- 1669
M +P Q Q +D R + ++Q P ++ L P+ P+
Sbjct: 326 GMQQPAYTQHQNMDQFQPRMMG---IQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQP 382
Query: 1670 ------PERSTFETEHAGQRDRYDRERDREPYFDRQSNVIADHRDFKRDRETHRDRDRDR 1723
P + F+ Q + ++ + + + I + + D R R R
Sbjct: 383 VIPPTPPVQQPFQASFQAQNEPL-TQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASR 441
Query: 1724 GVIDYDRDRFDRERRPRDDRAQS-YRDKKDHSSSRRGGFDRPSYDRKSDR 1772
R RR R R++S RD++ HS R R DR+ +R
Sbjct: 442 SPKRRRSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERR---DREKER 488
Score = 35.8 bits (81), Expect = 0.46
Identities = 51/209 (24%), Positives = 86/209 (41%), Gaps = 29/209 (13%)
Query: 1171 PEPGDGGEKMYPYHRDE---PPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYW 1227
P PG GG M P H + PP P+ P G P +R+ R++
Sbjct: 890 PPPGPGGFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRD-----GRQQPP 944
Query: 1228 RECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDEDYNREMERDMD 1287
++ ++ Q + ++ + PPS+ ++ P Q D NR+ + +
Sbjct: 945 QQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQP--------QQFRND-NRQ-QFNSG 994
Query: 1288 RDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYR 1347
RD +R R + ++N+ +R YG D++++ R+R P DR+R
Sbjct: 995 RDQERFGR--RSFGNRVENDRER-YGNRNDDRDNSNRDRREWGRRS-------PDRDRHR 1044
Query: 1348 DDRWREERNREH-GYDRDFRDRGELRIRE 1375
D R R+ H +RD RDR R +E
Sbjct: 1045 DLEERNRRSSGHRDRERDSRDRESRREKE 1073
Score = 33.9 bits (76), Expect = 1.8
Identities = 51/201 (25%), Positives = 76/201 (37%), Gaps = 46/201 (22%)
Query: 1134 IPPRRAGSR--ERGPPRGPGSRERGLGRSDFGRDRGPFRPE---------PGDGGEKMYP 1182
+PPR RGPP GPG G +GPF P PG GG P
Sbjct: 876 MPPRPMPPHMMHRGPPPGPG----GFAMPPPHGMKGPFPPHGPFVRPGGMPGLGGPGPGP 931
Query: 1183 ------YHRDEPPRAPWNHGE-------ERGHEEFPLDGRNAPMERERLDDW-------- 1221
R +PP+ P + ++ ++ P + P +++ +
Sbjct: 932 GGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQF 991
Query: 1222 ----DRERYWRECERDYQDDTLELY-NREDRFSAPPSRSHDGDRRGPWWDDWERDQDMDE 1276
D+ER+ R + ++ E Y NR D + RR P D +R +D++E
Sbjct: 992 NSGRDQERFGRRSFGNRVENDRERYGNRNDDRDNSNRDRREWGRRSP---DRDRHRDLEE 1048
Query: 1277 DYNREM-ERDMDRDV-DRISR 1295
R RD +RD DR SR
Sbjct: 1049 RNRRSSGHRDRERDSRDRESR 1069
Score = 33.5 bits (75), Expect = 2.3
Identities = 31/130 (23%), Positives = 47/130 (36%), Gaps = 45/130 (34%)
Query: 1478 DFGSEPQMADHLPPQESRLQNTSSRPGMYPP-----------PGSYRPPPPM---GKPPG 1523
D+ EP+ + +++ T++ PP P + PPPP G P
Sbjct: 266 DYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGFPGD 325
Query: 1524 SIVRPS------------------APPARSSVPVTRPP---------VPIPPPPP--PPP 1554
+ +P+ P VP+ PP +P PP PP P
Sbjct: 326 GMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPL--PPNGQMPGFGLLPTPPFPPMAQPV 383
Query: 1555 LPPPPPVIKP 1564
+PP PPV +P
Sbjct: 384 IPPTPPVQQP 393
Score = 32.7 bits (73), Expect = 3.9
Identities = 28/90 (31%), Positives = 30/90 (33%), Gaps = 17/90 (18%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPP----VMPP 567
G +MPPP M P P P V P + P L P PG P PP
Sbjct: 895 GGFAMPPP----HGMKGPFPPHGPFVRPGGM------PGLGGPGPGPGGPEDRDGRQQPP 944
Query: 568 SLPTSVP---PPGMPPSLSSAGPPPVLPPP 594
P P P P PPP PP
Sbjct: 945 QQPQQQPQPQAPQQPQQQQQQQPPPSQQPP 974
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 95.5 bits (236), Expect = 5e-19
Identities = 239/1022 (23%), Positives = 330/1022 (32%), Gaps = 201/1022 (19%)
Query: 29 EASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQ-----PHHLPP 83
++S PG+ S + SS F L + Q + Q V+Q P +
Sbjct: 149 KSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208
Query: 84 PPL---PPPPVMPGGGYG-------------DWQPPPPPMPPPPGPALSYQ---KQQQYK 124
PPL PP P+ G G Q P PPG Q + Q
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268
Query: 125 HQMLHHQRDGP---------------------PGLVPMELESPPESPPVPPGSYMPPSQS 163
H L QRD P P++ +P + P PG
Sbjct: 269 HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328
Query: 164 YMPPPQPPPSYYPPTSSQP--YLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS 221
PP QP P + QP PP QP + PP+Q P + S S
Sbjct: 329 AKPPAQPS-GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS----- 382
Query: 222 QSYLPSSQASPSRPSQGHSKSQLLAP-PPPSAPPGNKTTVQQEP-LESGAK---NKSTEQ 276
S P +A P G + +Q P PP+ G + Q+P L+S AK T
Sbjct: 383 -SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 277 QQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPE---PVKEE 333
QQ P P+ + S QQ P GP AK P+ P K
Sbjct: 442 QQPGPGKIPAQQAGPGK---------TSAQQTGPTKPPSQLPGP--AKPPPQQPGPAKPP 490
Query: 334 VTVPATSQVP-ESPSSEEPPLPPPNEEVPPPLPP--EEPQSEDPEEDARLKQLQAAAAHW 390
P +++ P + P S +PP P P P P +P S+ P Q + A
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
Query: 391 QQHQQHRVGFQYQG-IMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQ 449
Q V G +Q T Q Q + P I + +L + ++ F
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL--PKTICPLCNTTELLLHVPEKANFN 608
Query: 450 HLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQ 509
E Q L + L E K+W MK +
Sbjct: 609 TC-----TECQTTVCSLCGFNPNPHLTEV-KEWLCLNCQMK------------------R 644
Query: 510 YMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPAT-------VPPPGMPP 562
+G P P P ++ T V S P P A P P PP
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
Query: 563 P-VMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP------ 615
P V P+L S PS + PP SLS PP PS AP
Sbjct: 705 PLVKQPTLHGS-------PSAKAKQPPEA---DSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 616 ------PPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPA 669
P L SSAT P IP SS SQ EK P
Sbjct: 755 KQPKMVKPTTDLVSSSSATTKPDIP--------------------SSKVQSQAEEKTTP- 793
Query: 670 LLPTPVSFGSAPPTTYHPPL-QSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPS 728
P+ SA P+ PP + P + P S S + S + G+ P
Sbjct: 794 ----PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 729 QPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP--KGPRFE 786
Q K + P +P GPR P + + + + P+P + RF
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR---PTAGQTVPTPQQSPKPQEQSRRFS 906
Query: 787 ---GNRPDGPR--PRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSG---PQWK 838
G+ D P+ P G +G AS T QSG P +
Sbjct: 907 LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 839 GPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQS 898
P P+ Q P SQ P S + P A K+ ++ + AA+ + KA Q+
Sbjct: 967 APAPS------QPPTSQGPPKSTGQAPPAPA-----KSIPVKKETKAPAAEKLEPKAEQA 1015
Query: 899 -NENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQST 957
++++++PP P++ S +S+ + KA P L P P +ST
Sbjct: 1016 PTVKRTETEKKPP-------PIKDS------KSLTAEPQKA---VLPTKLEKSPKP-EST 1058
Query: 958 FP 959
P
Sbjct: 1059 CP 1060
Score = 82.4 bits (202), Expect = 4e-15
Identities = 190/863 (22%), Positives = 290/863 (33%), Gaps = 153/863 (17%)
Query: 226 PSSQASPSRPSQGHSKSQLLA--PPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEP 283
P++ SPS H K +L + PP S P + Q L + +Q P
Sbjct: 73 PAAAESPSM----HRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR 128
Query: 284 DPSTMT----------PQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEE 333
PST++ +E + L + + V +K P E +EE
Sbjct: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEE 188
Query: 334 VTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP-EEDARLKQLQAAAAHWQQ 392
T E E PP ++ P P+P ++ DP ++D K + +
Sbjct: 189 TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS------- 241
Query: 393 HQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPH----IQTMSVDMQLRHYEMQQQQF 448
QQ ++I PP IQ + Q H ++ Q+
Sbjct: 242 ------------------------QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRD 277
Query: 449 QHLYQEWEREFQLWEEQLHSYPH--KDQLQEYE--KQWKTWQGHMKATQSYLQEKVNSFQ 504
Q + + E S P K +Q+ K GH K+ +
Sbjct: 278 ASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG 337
Query: 505 NMKNQYMGNMSMPPPFVPYSQMPPPL----PTMPPPVLPPSLPPPVMPPALPATVPPPGM 560
K ++ PP P PP P PP S P P A PPG+
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 561 -------PPPVMPPSLPTSVPPP-GMPPSLSSAGPPPVLPPPSLSSAGP---PPVLPPPS 609
P P PP+ P P P L S P + GP P P
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 610 LSS------TAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQ-V 662
+S T PP +P P A PPP P P P PPQ + PP+ S++
Sbjct: 458 KTSAQQTGPTKPPSQLPGP----AKPPPQQPGPAKP---PPQQPGSAKPPSQQPGSTKPP 510
Query: 663 PEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLS--KSALPYSSFSSDQGL 720
P++P PA P+P GS P + P SA PS Q S A S +S P S S + L
Sbjct: 511 PQQPGPA-KPSPQQPGSTKPPSQQP--GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 721 GESSAAPSQPITAVKDMPV-------RSGGLLPDPPRSSYLESPR-----------GPRF 762
+ +PS + +P + LL P ++++ P
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627
Query: 763 DGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYI 822
E L C+ R G P P+P+ + P T + + +
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDL-APVPSSPQPKLKTAPVTTTSA----VSKSSPQPQQT 682
Query: 823 TPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSA 882
+P +P+Q K P+P +QP P + K+P S ++ K S
Sbjct: 683 SPKKDAAPKQD--LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS- 739
Query: 883 AFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVT 942
V + Q ++D + + PK V+ + + A T
Sbjct: 740 ----------VPSEQDKAPVADDKPKQPKM---------------VKPTTDLVSSSSATT 774
Query: 943 QPVPLANKPVPAQSTFPSKTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPR 1002
+P ++K QS KT + T S F P G + ++ K +PR
Sbjct: 775 KPDIPSSK---VQSQAEEKT-----TPPLKTDSAKPSQSFPPTGEKVSPFDS---KAIPR 823
Query: 1003 PDNRDNRLEGNRGNSSSYRGPGQ 1025
P + D+++ + G SS +G Q
Sbjct: 824 PAS-DSKIISHPGPSSESKGQKQ 845
Score = 74.3 bits (181), Expect = 1e-12
Identities = 117/432 (27%), Positives = 149/432 (34%), Gaps = 92/432 (21%)
Query: 17 PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVL 76
PPV PP P GP + PA + S S + L Q + + Q
Sbjct: 351 PPVQPPGTTKPPAQPLGP----AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ--- 403
Query: 77 QPHHLPPPP----LPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQR 132
QP PP P P G + P P P P QQ Q+
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463
Query: 133 DGPPGLVPMELESPPESPPVPPGSYMPPSQ---SYMPPPQPPPSYYPPTSSQPYLPPAQP 189
GP P +L P + PP PG PP Q S PP Q P S PP QP PA+P
Sbjct: 464 TGPTK-PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ-QP--GPAKP 519
Query: 190 SPSQ----SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLL 245
SP Q PPSQ P + S+ S + S QS P SQ +P Q + S
Sbjct: 520 SPQQPGSTKPPSQQ---PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Query: 246 APPPPSAPPG------NKTTVQQEPLESGAKNKSTEQQQAAP-----EPDPSTMTPQEQQ 294
PP P N T + E N TE Q P+P +E
Sbjct: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE-- 634
Query: 295 QYWYRQHLLSLQQRTKVHLPGH------------KKGPV-----VAKDTPEPVKEEVTVP 337
W L L + K L G K PV V+K +P+P + T P
Sbjct: 635 --W-----LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP---QQTSP 684
Query: 338 ATSQVP-----ESPSSEEPP-----------------LPPPNEEVPPPLPPEEP-----Q 370
P ++P ++PP PP + + P PP+EP Q
Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
Query: 371 SEDPEEDARLKQ 382
+ P D + KQ
Sbjct: 745 DKAPVADDKPKQ 756
Score = 68.2 bits (165), Expect = 8e-11
Identities = 64/231 (27%), Positives = 91/231 (39%), Gaps = 31/231 (13%)
Query: 517 PPPF-----VPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPT 571
P PF + S PPP P PPP PPP PP P +PPP P P + P
Sbjct: 2390 PRPFFRSSSLDISAQPPPPPPPPPP------PPPPPPPPPPPPLPPPTSPKPTILPKKKL 2443
Query: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPP-----LSS 626
+V P + + L S G LP + +TAPPPV P P L
Sbjct: 2444 TVASPVTTATPLFDAVTTLETTAVLRSNG----LPVTRICTTAPPPVPPKPSSIPSGLVF 2499
Query: 627 ATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYH 686
P PP P+ + PQL P ++ + + + KP L + ++ Y
Sbjct: 2500 THRPEPSKPPIAPKPVIPQL------PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYK 2553
Query: 687 PPLQSAGPSEQVNSKAPLSKSALPYS----SFSSDQGLGESSAAPSQPITA 733
P ++ S N +P +L + + S+ G S+A SQ IT+
Sbjct: 2554 LPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA-SQAITS 2603
Score = 66.2 bits (160), Expect = 3e-10
Identities = 134/661 (20%), Positives = 210/661 (31%), Gaps = 96/661 (14%)
Query: 18 PVPPPPPVALPEASPGPGYSSS--TTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75
PV P P +P GPG +S+ T P P S Q+
Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS-----------------------QLPGP 476
Query: 76 LQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135
+P P P PPP PG Q P PPP P + QQ Q+
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ--- 533
Query: 136 PGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSP 195
PG + P + P S P SQ+ P PP+ P PP+Q P
Sbjct: 534 PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ----PPSQGLPKTIC 589
Query: 196 PSQSYL-----APTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRP------SQGHSKSQL 244
P + P + ++ + Q+ + + P+ + + +
Sbjct: 590 PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD 649
Query: 245 LAPPPPSAPPGNKTTV----------QQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQ 294
LAP P S P KT +P ++ K + +Q + P+P P +Q
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
Query: 295 QYWYRQHLLSLQQRTKVH------------LPGHKKGPVVAKDTPEPVKEEVTVPATSQV 342
+ +Q + +P + VA D P+ K + P T V
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPK--MVKPTTDLV 767
Query: 343 PESPSSEEPPLPPPN------EEVPPPLPPE--EPQSEDPEEDARLKQLQAAAAHWQQHQ 394
S ++ +P +P E+ PPL + +P P ++ + A
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 395 QHRV---GFQYQGIMQKHT---QLQQILQQYQQIIQPPPHIQTMSVDMQL-------RHY 441
+ G + QK Q ++ ++ Q + P P + M
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 442 EMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVN 501
+ Q QE R F L + P E T G + + + + +
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE----TVTGKLFGFGASIFSQAS 943
Query: 502 SFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVP-PPGM 560
+ + Q G S P P Q P P + PP P PPA ++P
Sbjct: 944 NLISTAGQ-PGPHSQSGPGAPMKQAPAP--SQPPTSQGPPKSTGQAPPAPAKSIPVKKET 1000
Query: 561 PPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP 620
P P + P + + + PPP+ SL++ VLP S P P
Sbjct: 1001 KAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Query: 621 L 621
L
Sbjct: 1061 L 1061
Score = 58.5 bits (140), Expect = 7e-08
Identities = 59/196 (30%), Positives = 84/196 (42%), Gaps = 27/196 (13%)
Query: 1463 LKMLREQKE-QLQKMKDFGSEPQMADHLP------PQESRLQNTSSRPGMYPPPGSYRPP 1515
L+ R++KE + ++ K SE + DH P P + +L T G G +P
Sbjct: 2317 LEAYRDKKELEAERTKSSLSET-VFDHPPSSVIALPMKEQLSTTYFTSG--ETFGQEKPA 2373
Query: 1516 P--PMGKPPGSIVRPSAPP--ARSSVPVTR---PPVPIPPPPPPPPLPPPPPVIKPQTSA 1568
P G P S + P SS+ ++ PP P PPPPPPPP PPPPP + P TS
Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Query: 1569 VEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP-----V 1623
+ T ++ ET A+ + LP + ++ PPP P +
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493
Query: 1624 PMGM-----PPMSKPP 1634
P G+ P SKPP
Sbjct: 2494 PSGLVFTHRPEPSKPP 2509
Score = 53.9 bits (128), Expect = 2e-06
Identities = 60/255 (23%), Positives = 91/255 (35%), Gaps = 39/255 (15%)
Query: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200
+++ + P PP PP PP PPP PPP PPTS +P + P + SP + +
Sbjct: 2399 LDISAQPPPPPPPPPPPPPP-----PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA- 2452
Query: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV 260
TP + + ++ + + S LP ++ + P + P P S P G T
Sbjct: 2453 ---TPLFDAVTTLETTAVLRSNG-LPVTRICTTAPPP-------VPPKPSSIPSGLVFTH 2501
Query: 261 QQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLP------ 314
+ EP + K Q P+ + P+ L+L LP
Sbjct: 2502 RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPL 2561
Query: 315 ---GHKKGPVVAKDTPE-------------PVKEEVTVPATSQVPESPSSEEPPLPPPNE 358
+K P +K E P + TS SPS + + P
Sbjct: 2562 SPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFS 2621
Query: 359 EVPPPLPPEEPQSED 373
VPP E P S +
Sbjct: 2622 VVPPVTAVEIPISSE 2636
Score = 49.7 bits (117), Expect = 3e-05
Identities = 97/437 (22%), Positives = 147/437 (33%), Gaps = 111/437 (25%)
Query: 10 GSSHYPPPPVPPPP----PV----ALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQL 61
G P P P P PV A+ ++SP P +S AAP +Q L++
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAP---------KQDLSKA 697
Query: 62 QQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQ 121
P PPPL P + G P PP +LS K
Sbjct: 698 ----------------PEPKKPPPLVKQPTLHGS------PSAKAKQPPEADSLS--KPA 733
Query: 122 QYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQ 181
K + ++D P+ + P + V P + + S S P P S + +
Sbjct: 734 PPKEPSVPSEQDK----APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789
Query: 182 PYLPPAQPS---PSQS-PPSQSYLAPTPSYSSSSSSSQS-YLSH---SQSYLPSSQASPS 233
PP + PSQS PP+ ++P S + +S S +SH S Q P
Sbjct: 790 KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 234 RPSQGHSKSQLLAPPPPSA---------PPGNKTTVQQEPLESGAKNKSTEQQQA----- 279
+ + K+Q P P A PPG + T Q K EQ +
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909
Query: 280 -----APEPDPSTMTPQEQQQ----------YWYRQHLLSLQQRTKVHLPGHKKGPVVAK 324
AP+ P+T PQE + +L+S + H P+
Sbjct: 910 GSITDAPKSQPTT--PQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Query: 325 DTPE-----------------------PVKEEVTVPATSQVPESPSSEEPPL--PPPNEE 359
P PVK+E PA ++ P +E+ P E+
Sbjct: 968 PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL--EPKAEQAPTVKRTETEK 1025
Query: 360 VPPPLPPEEPQSEDPEE 376
PPP+ + + +P++
Sbjct: 1026 KPPPIKDSKSLTAEPQK 1042
Score = 48.9 bits (115), Expect = 5e-05
Identities = 87/388 (22%), Positives = 132/388 (34%), Gaps = 84/388 (21%)
Query: 11 SSHYPPPPVPPPPPVALPEASPGPGYSSSTTP---AAPSSSGFMSFREQHLAQLQQLQQM 67
S+ PPPP PPPPP P P P T+P P ++ +
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKK--LTVASPVTTATPLFDAV 2459
Query: 68 HQKQMQCVLQPHHLP--------PPPLPP-PPVMPGGGYGDWQPPPPPMPPPPGPALSYQ 118
+ VL+ + LP PPP+PP P +P G +P P P P P +
Sbjct: 2460 TTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQ- 2518
Query: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178
+P + P + P P G + S +
Sbjct: 2519 --------------------LPTTTQKPTDIHPKPTGLSLTSSMT-----------LNLV 2547
Query: 179 SSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQG 238
+S Y P+ SP ++S +P +S S + + ++ LPS +P+
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKS----SPRFSKSLTETYVVIT-----LPSEPGTPT----D 2594
Query: 239 HSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWY 298
S SQ + P +P +K V EP+ S P + P +Q +Y
Sbjct: 2595 SSASQAITSWPLGSP--SKDLVSVEPVFS------------VVPPVTAVEIPISSEQTFY 2640
Query: 299 RQHLLSLQQRTKVHLPGHKKG---PVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPP 355
L T V P + V T E K EV+ ++ SS +P
Sbjct: 2641 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIP- 2699
Query: 356 PNEEVPPPLPPEEPQSEDPE--EDARLK 381
P PL + E P+ ED +L+
Sbjct: 2700 -----PEPLALDNIHLEKPQYKEDGKLQ 2722
Score = 47.0 bits (110), Expect = 2e-04
Identities = 71/313 (22%), Positives = 111/313 (35%), Gaps = 23/313 (7%)
Query: 83 PPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKH--QMLHHQRDGPPGLVP 140
P L GG G P +P LS +++ + ++ + P G VP
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP 72
Query: 141 -MELESPPESPPVPPGSYMPPSQSYMPPP-----QPPPSYYPPTS---SQPYLPPAQPSP 191
ESP S PP QS PP QP S T S+ LP PS
Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132
Query: 192 SQSPPSQSYL--------APTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS-KS 242
S+S + P + S ++ + S + P S S SQ + K
Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192
Query: 243 QLLAPPPPSAPPGN-KTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQH 301
Q + P G K +QQ+P + K + + + P +++ Q+ ++ +
Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252
Query: 302 LLS--LQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEE 359
+Q T+ H K P+ + K+ V S P PS +PP+ P
Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312
Query: 360 VPPPLPPEEPQSE 372
PP P +S+
Sbjct: 313 KPPAQQPGHEKSQ 325
Score = 45.8 bits (107), Expect = 4e-04
Identities = 38/119 (31%), Positives = 48/119 (40%), Gaps = 27/119 (22%)
Query: 594 PSLSS--AGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPV 651
PS+SS A P P SL +A PP P PP PPP PPP P+
Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP-------------PL 2427
Query: 652 PPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALP 710
PP P P+P +LP ++P TT P + E + A L + LP
Sbjct: 2428 PP---------PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE---TTAVLRSNGLP 2474
Score = 42.0 bits (97), Expect = 0.006
Identities = 42/167 (25%), Positives = 54/167 (32%), Gaps = 29/167 (17%)
Query: 1500 SSRPGMYPP---PGSYRPP---PPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP 1553
+ +PG+ P PG + P P GK P P A+ + P T+PP +P P PP
Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP-TKPPSQLPGPAKPP 480
Query: 1554 PLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV 1613
P P P PQ + G + + P P P
Sbjct: 481 PQQPGPAKPPPQ----------------------QPGSAKPPSQQPGSTKPPPQQPGPAK 518
Query: 1614 HSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGE 1660
S P P P S P QQ ST V Q G+
Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
Score = 39.3 bits (90), Expect = 0.042
Identities = 39/165 (23%), Positives = 55/165 (33%), Gaps = 35/165 (21%)
Query: 1480 GSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPV 1539
G+ A L P + Q T S PG P + +PPG P+ P + P
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG----PKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 1540 TRPPVPIP-------PPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLN 1592
+ P P P P P PV +P + ++
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ------------------- 453
Query: 1593 SEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQ 1637
+T+A + P PP S +P P P P +KPPP Q
Sbjct: 454 -AGPGKTSAQQTGPTKPP----SQLPGPAKPPPQQPGPAKPPPQQ 493
Score = 39.3 bits (90), Expect = 0.042
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 2/69 (2%)
Query: 306 QQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLP 365
Q++ LP P P ++ ++Q P P PP PPP PPPLP
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 366 PEEPQSEDP 374
P P S P
Sbjct: 2429 P--PTSPKP 2435
Score = 37.7 bits (86), Expect = 0.12
Identities = 34/141 (24%), Positives = 47/141 (33%), Gaps = 11/141 (7%)
Query: 1496 LQNTSSRP-GMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPP 1554
+Q +P G+ PP +PP P+ K G P R + P I P
Sbjct: 196 VQKEQGKPEGIIKPPLQQQPPKPIPKQQG--------PGRDPLQQDGTPKSISSQQPEKI 247
Query: 1555 LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVH 1614
PP KP + + D D + Q ++ + PS P PP+
Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307
Query: 1615 SSIPPPGPVPMGMPPMSKPPP 1635
P PG P P K P
Sbjct: 308 Q--PTPGKPPAQQPGHEKSQP 326
Score = 37.0 bits (84), Expect = 0.21
Identities = 22/74 (29%), Positives = 28/74 (37%), Gaps = 3/74 (4%)
Query: 1486 ADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVP 1545
A P ++ Q T PG +PPP + PG P P + P +P
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP---QQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 1546 IPPPPPPPPLPPPP 1559
PPP P P P P
Sbjct: 508 KPPPQQPGPAKPSP 521
Score = 37.0 bits (84), Expect = 0.21
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 24/122 (19%)
Query: 89 PPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPE 148
PP P Y P P P SY +Q ++ Q L+HQ+ P ++ P
Sbjct: 3880 PPTSPYTQYQYSSPALPTQAPT-----SYTQQSHFEQQTLYHQQVSP-------YQTQPT 3927
Query: 149 SPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYS 208
V S+ P Q P P P PS Y P+Q Q P Q+ L P +
Sbjct: 3928 FQAVATMSFTPQVQ---PTPTPQPS---------YQLPSQMMVIQQKPRQTTLYLEPKIT 3975
Query: 209 SS 210
S+
Sbjct: 3976 SN 3977
Score = 36.2 bits (82), Expect = 0.36
Identities = 58/284 (20%), Positives = 97/284 (34%), Gaps = 39/284 (13%)
Query: 11 SSHYPPP--PVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68
S +PP V P A+P + S P++ S ++ + +Q+ ++
Sbjct: 803 SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKG------QKQVDPVQKKEEPK 856
Query: 69 QKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQML 128
+ Q + +P P P P P P G P P P P Q+Q + L
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP-------QEQSRRFSLNL 909
Query: 129 HHQRDGPPGLVPMELESPPESPPVP---------PGSYMPPSQSYMPPPQPPP-SYYPPT 178
D P +S P +P + S QP P S P
Sbjct: 910 GSITDAP--------KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
Query: 179 SSQPYLP-PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQ 237
+ P P+QP SQ PP + AP S ++ ++ P ++ +P+
Sbjct: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT---- 1017
Query: 238 GHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAP 281
+++ PPP + T Q+ + KS + + P
Sbjct: 1018 -VKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 35.0 bits (79), Expect = 0.79
Identities = 45/188 (23%), Positives = 58/188 (30%), Gaps = 42/188 (22%)
Query: 1468 EQKEQLQKMKDFGSEPQMADHLPPQESR----LQNTSSRPGMYPPP----GSYRPP-PPM 1518
+Q E+++ +P PQ LQ +SRP S +P P
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301
Query: 1519 GKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP----PPLPPPPPVIKPQTSAVEQERW 1574
KPP P PPA+ P P PP P PL P +KP
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP--------- 352
Query: 1575 DEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPP----PGPVPMGMPPM 1630
+ ++ A P P PP S P PGP + PP
Sbjct: 353 ----------------VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
Query: 1631 SKPPPVQQ 1638
P QQ
Sbjct: 397 VGKTPAQQ 404
Score = 34.7 bits (78), Expect = 1.0
Identities = 32/106 (30%), Positives = 42/106 (39%), Gaps = 22/106 (20%)
Query: 1482 EPQMADHLPPQESRLQNTSSRPGMYPP----PGSYRPPP-------PMGKPPGSIVRPSA 1530
+P A P Q + S +PG P PG +P P P + PGS +PSA
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS-AKPSA 541
Query: 1531 ---PPARSSVPVTRPPV-------PIPPPPPPPPLPPPPPVIKPQT 1566
PA+ S + PV P+ PP P PP P+T
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587
Score = 34.3 bits (77), Expect = 1.4
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 1595 FKSETAAIPSAPVLPPPPVHSSIPPPGPV-PMGMPPMSKPPP 1635
F+S + I + P PPPP PPP P P +PP + P P
Sbjct: 2394 FRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435
Score = 33.9 bits (76), Expect = 1.8
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 9/83 (10%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPAR---SSVPVTRPPVP 1545
+P Q++ TS++ P S P P KPP P+ PP + S+ P ++ P
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGP--AKPPPQQPGPAKPPPQQPGSAKPPSQQPGS 506
Query: 1546 IPPPP----PPPPLPPPPPVIKP 1564
PPP P P P P KP
Sbjct: 507 TKPPPQQPGPAKPSPQQPGSTKP 529
Score = 32.3 bits (72), Expect = 5.1
Identities = 43/197 (21%), Positives = 61/197 (30%), Gaps = 23/197 (11%)
Query: 1501 SRPGMYPPPGSYRPPPPMGK---PPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPP 1557
S PG + P+ K P + + S P +P P P P P +P
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891
Query: 1558 PPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQ-------------GLNSEFKSETAAIPS 1604
P KPQ EQ R + + D Q G + S+ + + S
Sbjct: 892 PQQSPKPQ----EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 1605 APVLPPPPVHSSIPPP---GPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGER 1661
P P S P P P P PP + I K + P E+
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 1662 ITLRPDPLPERSTFETE 1678
+ + + P ETE
Sbjct: 1008 LEPKAEQAPTVKRTETE 1024
Score = 32.0 bits (71), Expect = 6.7
Identities = 26/98 (26%), Positives = 36/98 (36%), Gaps = 14/98 (14%)
Query: 1481 SEPQMADHLPPQESR-LQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPS--------AP 1531
S PQ P +++ Q+ S P PP + P G P +P AP
Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAP 734
Query: 1532 PARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAV 1569
P SVP + P+ P P ++KP T V
Sbjct: 735 PKEPSVPSEQDKAPVADDK-----PKQPKMVKPTTDLV 767
Score = 31.6 bits (70), Expect = 8.8
Identities = 48/210 (22%), Positives = 78/210 (37%), Gaps = 25/210 (11%)
Query: 184 LPPAQPSPSQSPPSQSYLAPTPSYSSSSSSS---QSYLSHSQSYLPSSQASPSRPSQGHS 240
+PPA P SP P P+ SSS ++ Q L Q ++A +
Sbjct: 1125 MPPAPSGPKASP------MPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKE 1178
Query: 241 KSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQ-QYWYR 299
+ PP TT Q++ K+K++ Q+ P P+ + P+E++ + +
Sbjct: 1179 TLSMEKIPPMV------TTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 300 QHLLSLQQRTKVHLPGHKK-GPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNE 358
+ LL ++ T P KK P PE K ++ E P
Sbjct: 1233 KPLLEEKKPT----PEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEG 1288
Query: 359 EVPPP----LPPEEPQSEDPEEDARLKQLQ 384
+ P LP PQS E+D K ++
Sbjct: 1289 KQPQTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
Score = 31.6 bits (70), Expect = 8.8
Identities = 39/140 (27%), Positives = 52/140 (37%), Gaps = 25/140 (17%)
Query: 172 PSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQAS 231
P P T ++PP + SQ P PT Y+ SS + LP+ QA
Sbjct: 3856 PRTAPQTEFSQFIPPQTQTESQLVP------PTSPYTQYQYSSPA--------LPT-QAP 3900
Query: 232 PSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEP-LESGAKNKSTEQQQAAPEPDPSTMTP 290
S Q H + Q L S Q +P ++ A T Q Q P P PS P
Sbjct: 3901 TSYTQQSHFEQQTLYHQQVSP-------YQTQPTFQAVATMSFTPQVQPTPTPQPSYQLP 3953
Query: 291 QEQQ--QYWYRQHLLSLQQR 308
+ Q RQ L L+ +
Sbjct: 3954 SQMMVIQQKPRQTTLYLEPK 3973
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 95.5 bits (236), Expect = 5e-19
Identities = 239/1022 (23%), Positives = 330/1022 (32%), Gaps = 201/1022 (19%)
Query: 29 EASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQ-----PHHLPP 83
++S PG+ S + SS F L + Q + Q V+Q P +
Sbjct: 149 KSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIK 208
Query: 84 PPL---PPPPVMPGGGYG-------------DWQPPPPPMPPPPGPALSYQ---KQQQYK 124
PPL PP P+ G G Q P PPG Q + Q
Sbjct: 209 PPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTD 268
Query: 125 HQMLHHQRDGP---------------------PGLVPMELESPPESPPVPPGSYMPPSQS 163
H L QRD P P++ +P + P PG
Sbjct: 269 HAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP 328
Query: 164 YMPPPQPPPSYYPPTSSQP--YLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS 221
PP QP P + QP PP QP + PP+Q P + S S
Sbjct: 329 AKPPAQPS-GLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS----- 382
Query: 222 QSYLPSSQASPSRPSQGHSKSQLLAP-PPPSAPPGNKTTVQQEP-LESGAK---NKSTEQ 276
S P +A P G + +Q P PP+ G + Q+P L+S AK T
Sbjct: 383 -SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPV 441
Query: 277 QQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPE---PVKEE 333
QQ P P+ + S QQ P GP AK P+ P K
Sbjct: 442 QQPGPGKIPAQQAGPGK---------TSAQQTGPTKPPSQLPGP--AKPPPQQPGPAKPP 490
Query: 334 VTVPATSQVP-ESPSSEEPPLPPPNEEVPPPLPP--EEPQSEDPEEDARLKQLQAAAAHW 390
P +++ P + P S +PP P P P P +P S+ P Q + A
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPS 550
Query: 391 QQHQQHRVGFQYQG-IMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQ 449
Q V G +Q T Q Q + P I + +L + ++ F
Sbjct: 551 AQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGL--PKTICPLCNTTELLLHVPEKANFN 608
Query: 450 HLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQ 509
E Q L + L E K+W MK +
Sbjct: 609 TC-----TECQTTVCSLCGFNPNPHLTEV-KEWLCLNCQMK------------------R 644
Query: 510 YMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPAT-------VPPPGMPP 562
+G P P P ++ T V S P P A P P PP
Sbjct: 645 ALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPP 704
Query: 563 P-VMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP------ 615
P V P+L S PS + PP SLS PP PS AP
Sbjct: 705 PLVKQPTLHGS-------PSAKAKQPPEA---DSLSKPAPPKEPSVPSEQDKAPVADDKP 754
Query: 616 ------PPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPA 669
P L SSAT P IP SS SQ EK P
Sbjct: 755 KQPKMVKPTTDLVSSSSATTKPDIP--------------------SSKVQSQAEEKTTP- 793
Query: 670 LLPTPVSFGSAPPTTYHPPL-QSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPS 728
P+ SA P+ PP + P + P S S + S + G+ P
Sbjct: 794 ----PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 729 QPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP--KGPRFE 786
Q K + P +P GPR P + + + + P+P + RF
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR---PTAGQTVPTPQQSPKPQEQSRRFS 906
Query: 787 ---GNRPDGPR--PRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSG---PQWK 838
G+ D P+ P G +G AS T QSG P +
Sbjct: 907 LNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 839 GPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQS 898
P P+ Q P SQ P S + P A K+ ++ + AA+ + KA Q+
Sbjct: 967 APAPS------QPPTSQGPPKSTGQAPPAPA-----KSIPVKKETKAPAAEKLEPKAEQA 1015
Query: 899 -NENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLANKPVPAQST 957
++++++PP P++ S +S+ + KA P L P P +ST
Sbjct: 1016 PTVKRTETEKKPP-------PIKDS------KSLTAEPQKA---VLPTKLEKSPKP-EST 1058
Query: 958 FP 959
P
Sbjct: 1059 CP 1060
Score = 82.4 bits (202), Expect = 4e-15
Identities = 190/863 (22%), Positives = 290/863 (33%), Gaps = 153/863 (17%)
Query: 226 PSSQASPSRPSQGHSKSQLLA--PPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEP 283
P++ SPS H K +L + PP S P + Q L + +Q P
Sbjct: 73 PAAAESPSM----HRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR 128
Query: 284 DPSTMT----------PQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEE 333
PST++ +E + L + + V +K P E +EE
Sbjct: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEE 188
Query: 334 VTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP-EEDARLKQLQAAAAHWQQ 392
T E E PP ++ P P+P ++ DP ++D K + +
Sbjct: 189 TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS------- 241
Query: 393 HQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPH----IQTMSVDMQLRHYEMQQQQF 448
QQ ++I PP IQ + Q H ++ Q+
Sbjct: 242 ------------------------QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRD 277
Query: 449 QHLYQEWEREFQLWEEQLHSYPH--KDQLQEYE--KQWKTWQGHMKATQSYLQEKVNSFQ 504
Q + + E S P K +Q+ K GH K+ +
Sbjct: 278 ASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSG 337
Query: 505 NMKNQYMGNMSMPPPFVPYSQMPPPL----PTMPPPVLPPSLPPPVMPPALPATVPPPGM 560
K ++ PP P PP P PP S P P A PPG+
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 561 -------PPPVMPPSLPTSVPPP-GMPPSLSSAGPPPVLPPPSLSSAGP---PPVLPPPS 609
P P PP+ P P P L S P + GP P P
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 610 LSS------TAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQ-V 662
+S T PP +P P A PPP P P P PPQ + PP+ S++
Sbjct: 458 KTSAQQTGPTKPPSQLPGP----AKPPPQQPGPAKP---PPQQPGSAKPPSQQPGSTKPP 510
Query: 663 PEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLS--KSALPYSSFSSDQGL 720
P++P PA P+P GS P + P SA PS Q S A S +S P S S + L
Sbjct: 511 PQQPGPA-KPSPQQPGSTKPPSQQP--GSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPL 567
Query: 721 GESSAAPSQPITAVKDMPV-------RSGGLLPDPPRSSYLESPR-----------GPRF 762
+ +PS + +P + LL P ++++ P
Sbjct: 568 QPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNP 627
Query: 763 DGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYI 822
E L C+ R G P P+P+ + P T + + +
Sbjct: 628 HLTEVKEWLCLNCQMKRALGGDL-APVPSSPQPKLKTAPVTTTSA----VSKSSPQPQQT 682
Query: 823 TPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSA 882
+P +P+Q K P+P +QP P + K+P S ++ K S
Sbjct: 683 SPKKDAAPKQD--LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPS- 739
Query: 883 AFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVT 942
V + Q ++D + + PK V+ + + A T
Sbjct: 740 ----------VPSEQDKAPVADDKPKQPKM---------------VKPTTDLVSSSSATT 774
Query: 943 QPVPLANKPVPAQSTFPSKTGGMEGGTAVATSSLTADNDFKPVGIGLPHSENNQDKGLPR 1002
+P ++K QS KT + T S F P G + ++ K +PR
Sbjct: 775 KPDIPSSK---VQSQAEEKT-----TPPLKTDSAKPSQSFPPTGEKVSPFDS---KAIPR 823
Query: 1003 PDNRDNRLEGNRGNSSSYRGPGQ 1025
P + D+++ + G SS +G Q
Sbjct: 824 PAS-DSKIISHPGPSSESKGQKQ 845
Score = 74.3 bits (181), Expect = 1e-12
Identities = 117/432 (27%), Positives = 149/432 (34%), Gaps = 92/432 (21%)
Query: 17 PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVL 76
PPV PP P GP + PA + S S + L Q + + Q
Sbjct: 351 PPVQPPGTTKPPAQPLGP----AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ--- 403
Query: 77 QPHHLPPPP----LPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQR 132
QP PP P P G + P P P P QQ Q+
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463
Query: 133 DGPPGLVPMELESPPESPPVPPGSYMPPSQ---SYMPPPQPPPSYYPPTSSQPYLPPAQP 189
GP P +L P + PP PG PP Q S PP Q P S PP QP PA+P
Sbjct: 464 TGPTK-PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQ-QP--GPAKP 519
Query: 190 SPSQ----SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLL 245
SP Q PPSQ P + S+ S + S QS P SQ +P Q + S
Sbjct: 520 SPQQPGSTKPPSQQ---PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA 576
Query: 246 APPPPSAPPG------NKTTVQQEPLESGAKNKSTEQQQAAP-----EPDPSTMTPQEQQ 294
PP P N T + E N TE Q P+P +E
Sbjct: 577 KQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE-- 634
Query: 295 QYWYRQHLLSLQQRTKVHLPGH------------KKGPV-----VAKDTPEPVKEEVTVP 337
W L L + K L G K PV V+K +P+P + T P
Sbjct: 635 --W-----LCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQP---QQTSP 684
Query: 338 ATSQVP-----ESPSSEEPP-----------------LPPPNEEVPPPLPPEEP-----Q 370
P ++P ++PP PP + + P PP+EP Q
Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744
Query: 371 SEDPEEDARLKQ 382
+ P D + KQ
Sbjct: 745 DKAPVADDKPKQ 756
Score = 68.2 bits (165), Expect = 8e-11
Identities = 64/231 (27%), Positives = 91/231 (39%), Gaps = 31/231 (13%)
Query: 517 PPPF-----VPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPT 571
P PF + S PPP P PPP PPP PP P +PPP P P + P
Sbjct: 2390 PRPFFRSSSLDISAQPPPPPPPPPP------PPPPPPPPPPPPLPPPTSPKPTILPKKKL 2443
Query: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPP-----LSS 626
+V P + + L S G LP + +TAPPPV P P L
Sbjct: 2444 TVASPVTTATPLFDAVTTLETTAVLRSNG----LPVTRICTTAPPPVPPKPSSIPSGLVF 2499
Query: 627 ATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYH 686
P PP P+ + PQL P ++ + + + KP L + ++ Y
Sbjct: 2500 THRPEPSKPPIAPKPVIPQL------PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYK 2553
Query: 687 PPLQSAGPSEQVNSKAPLSKSALPYS----SFSSDQGLGESSAAPSQPITA 733
P ++ S N +P +L + + S+ G S+A SQ IT+
Sbjct: 2554 LPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA-SQAITS 2603
Score = 66.2 bits (160), Expect = 3e-10
Identities = 134/661 (20%), Positives = 210/661 (31%), Gaps = 96/661 (14%)
Query: 18 PVPPPPPVALPEASPGPGYSSS--TTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCV 75
PV P P +P GPG +S+ T P P S Q+
Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS-----------------------QLPGP 476
Query: 76 LQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGP 135
+P P P PPP PG Q P PPP P + QQ Q+
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQ--- 533
Query: 136 PGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSP 195
PG + P + P S P SQ+ P PP+ P PP+Q P
Sbjct: 534 PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQ----PPSQGLPKTIC 589
Query: 196 PSQSYL-----APTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRP------SQGHSKSQL 244
P + P + ++ + Q+ + + P+ + + +
Sbjct: 590 PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGD 649
Query: 245 LAPPPPSAPPGNKTTV----------QQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQ 294
LAP P S P KT +P ++ K + +Q + P+P P +Q
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
Query: 295 QYWYRQHLLSLQQRTKVH------------LPGHKKGPVVAKDTPEPVKEEVTVPATSQV 342
+ +Q + +P + VA D P+ K + P T V
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPK--MVKPTTDLV 767
Query: 343 PESPSSEEPPLPPPN------EEVPPPLPPE--EPQSEDPEEDARLKQLQAAAAHWQQHQ 394
S ++ +P +P E+ PPL + +P P ++ + A
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 395 QHRV---GFQYQGIMQKHT---QLQQILQQYQQIIQPPPHIQTMSVDMQL-------RHY 441
+ G + QK Q ++ ++ Q + P P + M
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 442 EMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVN 501
+ Q QE R F L + P E T G + + + + +
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQE----TVTGKLFGFGASIFSQAS 943
Query: 502 SFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVP-PPGM 560
+ + Q G S P P Q P P + PP P PPA ++P
Sbjct: 944 NLISTAGQ-PGPHSQSGPGAPMKQAPAP--SQPPTSQGPPKSTGQAPPAPAKSIPVKKET 1000
Query: 561 PPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP 620
P P + P + + + PPP+ SL++ VLP S P P
Sbjct: 1001 KAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Query: 621 L 621
L
Sbjct: 1061 L 1061
Score = 58.5 bits (140), Expect = 7e-08
Identities = 59/196 (30%), Positives = 84/196 (42%), Gaps = 27/196 (13%)
Query: 1463 LKMLREQKE-QLQKMKDFGSEPQMADHLP------PQESRLQNTSSRPGMYPPPGSYRPP 1515
L+ R++KE + ++ K SE + DH P P + +L T G G +P
Sbjct: 2317 LEAYRDKKELEAERTKSSLSET-VFDHPPSSVIALPMKEQLSTTYFTSG--ETFGQEKPA 2373
Query: 1516 P--PMGKPPGSIVRPSAPP--ARSSVPVTR---PPVPIPPPPPPPPLPPPPPVIKPQTSA 1568
P G P S + P SS+ ++ PP P PPPPPPPP PPPPP + P TS
Sbjct: 2374 SQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433
Query: 1569 VEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGP-----V 1623
+ T ++ ET A+ + LP + ++ PPP P +
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493
Query: 1624 PMGM-----PPMSKPP 1634
P G+ P SKPP
Sbjct: 2494 PSGLVFTHRPEPSKPP 2509
Score = 53.9 bits (128), Expect = 2e-06
Identities = 60/255 (23%), Positives = 91/255 (35%), Gaps = 39/255 (15%)
Query: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200
+++ + P PP PP PP PPP PPP PPTS +P + P + SP + +
Sbjct: 2399 LDISAQPPPPPPPPPPPPPP-----PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTA- 2452
Query: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV 260
TP + + ++ + + S LP ++ + P + P P S P G T
Sbjct: 2453 ---TPLFDAVTTLETTAVLRSNG-LPVTRICTTAPPP-------VPPKPSSIPSGLVFTH 2501
Query: 261 QQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLP------ 314
+ EP + K Q P+ + P+ L+L LP
Sbjct: 2502 RPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPL 2561
Query: 315 ---GHKKGPVVAKDTPE-------------PVKEEVTVPATSQVPESPSSEEPPLPPPNE 358
+K P +K E P + TS SPS + + P
Sbjct: 2562 SPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFS 2621
Query: 359 EVPPPLPPEEPQSED 373
VPP E P S +
Sbjct: 2622 VVPPVTAVEIPISSE 2636
Score = 49.7 bits (117), Expect = 3e-05
Identities = 97/437 (22%), Positives = 147/437 (33%), Gaps = 111/437 (25%)
Query: 10 GSSHYPPPPVPPPP----PV----ALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQL 61
G P P P P PV A+ ++SP P +S AAP +Q L++
Sbjct: 647 GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAP---------KQDLSKA 697
Query: 62 QQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQ 121
P PPPL P + G P PP +LS K
Sbjct: 698 ----------------PEPKKPPPLVKQPTLHGS------PSAKAKQPPEADSLS--KPA 733
Query: 122 QYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQ 181
K + ++D P+ + P + V P + + S S P P S + +
Sbjct: 734 PPKEPSVPSEQDK----APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE 789
Query: 182 PYLPPAQPS---PSQS-PPSQSYLAPTPSYSSSSSSSQS-YLSH---SQSYLPSSQASPS 233
PP + PSQS PP+ ++P S + +S S +SH S Q P
Sbjct: 790 KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 234 RPSQGHSKSQLLAPPPPSA---------PPGNKTTVQQEPLESGAKNKSTEQQQA----- 279
+ + K+Q P P A PPG + T Q K EQ +
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909
Query: 280 -----APEPDPSTMTPQEQQQ----------YWYRQHLLSLQQRTKVHLPGHKKGPVVAK 324
AP+ P+T PQE + +L+S + H P+
Sbjct: 910 GSITDAPKSQPTT--PQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQA 967
Query: 325 DTPE-----------------------PVKEEVTVPATSQVPESPSSEEPPL--PPPNEE 359
P PVK+E PA ++ P +E+ P E+
Sbjct: 968 PAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKL--EPKAEQAPTVKRTETEK 1025
Query: 360 VPPPLPPEEPQSEDPEE 376
PPP+ + + +P++
Sbjct: 1026 KPPPIKDSKSLTAEPQK 1042
Score = 48.9 bits (115), Expect = 5e-05
Identities = 87/388 (22%), Positives = 132/388 (34%), Gaps = 84/388 (21%)
Query: 11 SSHYPPPPVPPPPPVALPEASPGPGYSSSTTP---AAPSSSGFMSFREQHLAQLQQLQQM 67
S+ PPPP PPPPP P P P T+P P ++ +
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKK--LTVASPVTTATPLFDAV 2459
Query: 68 HQKQMQCVLQPHHLP--------PPPLPP-PPVMPGGGYGDWQPPPPPMPPPPGPALSYQ 118
+ VL+ + LP PPP+PP P +P G +P P P P P +
Sbjct: 2460 TTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQ- 2518
Query: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178
+P + P + P P G + S +
Sbjct: 2519 --------------------LPTTTQKPTDIHPKPTGLSLTSSMT-----------LNLV 2547
Query: 179 SSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQG 238
+S Y P+ SP ++S +P +S S + + ++ LPS +P+
Sbjct: 2548 TSADYKLPSPTSPLSPHSNKS----SPRFSKSLTETYVVIT-----LPSEPGTPT----D 2594
Query: 239 HSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWY 298
S SQ + P +P +K V EP+ S P + P +Q +Y
Sbjct: 2595 SSASQAITSWPLGSP--SKDLVSVEPVFS------------VVPPVTAVEIPISSEQTFY 2640
Query: 299 RQHLLSLQQRTKVHLPGHKKG---PVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPP 355
L T V P + V T E K EV+ ++ SS +P
Sbjct: 2641 ISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIP- 2699
Query: 356 PNEEVPPPLPPEEPQSEDPE--EDARLK 381
P PL + E P+ ED +L+
Sbjct: 2700 -----PEPLALDNIHLEKPQYKEDGKLQ 2722
Score = 47.0 bits (110), Expect = 2e-04
Identities = 71/313 (22%), Positives = 111/313 (35%), Gaps = 23/313 (7%)
Query: 83 PPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKH--QMLHHQRDGPPGLVP 140
P L GG G P +P LS +++ + ++ + P G VP
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP 72
Query: 141 -MELESPPESPPVPPGSYMPPSQSYMPPP-----QPPPSYYPPTS---SQPYLPPAQPSP 191
ESP S PP QS PP QP S T S+ LP PS
Sbjct: 73 PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPST 132
Query: 192 SQSPPSQSYL--------APTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS-KS 242
S+S + P + S ++ + S + P S S SQ + K
Sbjct: 133 ISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKK 192
Query: 243 QLLAPPPPSAPPGN-KTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQH 301
Q + P G K +QQ+P + K + + + P +++ Q+ ++ +
Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPP 252
Query: 302 LLS--LQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEE 359
+Q T+ H K P+ + K+ V S P PS +PP+ P
Sbjct: 253 GTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPG 312
Query: 360 VPPPLPPEEPQSE 372
PP P +S+
Sbjct: 313 KPPAQQPGHEKSQ 325
Score = 45.8 bits (107), Expect = 4e-04
Identities = 38/119 (31%), Positives = 48/119 (40%), Gaps = 27/119 (22%)
Query: 594 PSLSS--AGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPV 651
PS+SS A P P SL +A PP P PP PPP PPP P+
Sbjct: 2381 PSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPP-------------PL 2427
Query: 652 PPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALP 710
PP P P+P +LP ++P TT P + E + A L + LP
Sbjct: 2428 PP---------PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLE---TTAVLRSNGLP 2474
Score = 42.0 bits (97), Expect = 0.006
Identities = 42/167 (25%), Positives = 54/167 (32%), Gaps = 29/167 (17%)
Query: 1500 SSRPGMYPP---PGSYRPP---PPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP 1553
+ +PG+ P PG + P P GK P P A+ + P T+PP +P P PP
Sbjct: 422 AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP-TKPPSQLPGPAKPP 480
Query: 1554 PLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPV 1613
P P P PQ + G + + P P P
Sbjct: 481 PQQPGPAKPPPQ----------------------QPGSAKPPSQQPGSTKPPPQQPGPAK 518
Query: 1614 HSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGE 1660
S P P P S P QQ ST V Q G+
Sbjct: 519 PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
Score = 39.3 bits (90), Expect = 0.042
Identities = 39/165 (23%), Positives = 55/165 (33%), Gaps = 35/165 (21%)
Query: 1480 GSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPV 1539
G+ A L P + Q T S PG P + +PPG P+ P + P
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG----PKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 1540 TRPPVPIP-------PPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLN 1592
+ P P P P P PV +P + ++
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ------------------- 453
Query: 1593 SEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQ 1637
+T+A + P PP S +P P P P +KPPP Q
Sbjct: 454 -AGPGKTSAQQTGPTKPP----SQLPGPAKPPPQQPGPAKPPPQQ 493
Score = 39.3 bits (90), Expect = 0.042
Identities = 22/69 (31%), Positives = 28/69 (40%), Gaps = 2/69 (2%)
Query: 306 QQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLP 365
Q++ LP P P ++ ++Q P P PP PPP PPPLP
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 366 PEEPQSEDP 374
P P S P
Sbjct: 2429 P--PTSPKP 2435
Score = 37.7 bits (86), Expect = 0.12
Identities = 34/141 (24%), Positives = 47/141 (33%), Gaps = 11/141 (7%)
Query: 1496 LQNTSSRP-GMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPP 1554
+Q +P G+ PP +PP P+ K G P R + P I P
Sbjct: 196 VQKEQGKPEGIIKPPLQQQPPKPIPKQQG--------PGRDPLQQDGTPKSISSQQPEKI 247
Query: 1555 LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVH 1614
PP KP + + D D + Q ++ + PS P PP+
Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307
Query: 1615 SSIPPPGPVPMGMPPMSKPPP 1635
P PG P P K P
Sbjct: 308 Q--PTPGKPPAQQPGHEKSQP 326
Score = 37.0 bits (84), Expect = 0.21
Identities = 22/74 (29%), Positives = 28/74 (37%), Gaps = 3/74 (4%)
Query: 1486 ADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVP 1545
A P ++ Q T PG +PPP + PG P P + P +P
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP---QQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 1546 IPPPPPPPPLPPPP 1559
PPP P P P P
Sbjct: 508 KPPPQQPGPAKPSP 521
Score = 37.0 bits (84), Expect = 0.21
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 24/122 (19%)
Query: 89 PPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPE 148
PP P Y P P P SY +Q ++ Q L+HQ+ P ++ P
Sbjct: 3880 PPTSPYTQYQYSSPALPTQAPT-----SYTQQSHFEQQTLYHQQVSP-------YQTQPT 3927
Query: 149 SPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYS 208
V S+ P Q P P P PS Y P+Q Q P Q+ L P +
Sbjct: 3928 FQAVATMSFTPQVQ---PTPTPQPS---------YQLPSQMMVIQQKPRQTTLYLEPKIT 3975
Query: 209 SS 210
S+
Sbjct: 3976 SN 3977
Score = 36.2 bits (82), Expect = 0.36
Identities = 58/284 (20%), Positives = 97/284 (34%), Gaps = 39/284 (13%)
Query: 11 SSHYPPP--PVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68
S +PP V P A+P + S P++ S ++ + +Q+ ++
Sbjct: 803 SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKG------QKQVDPVQKKEEPK 856
Query: 69 QKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQML 128
+ Q + +P P P P P P G P P P P Q+Q + L
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKP-------QEQSRRFSLNL 909
Query: 129 HHQRDGPPGLVPMELESPPESPPVP---------PGSYMPPSQSYMPPPQPPP-SYYPPT 178
D P +S P +P + S QP P S P
Sbjct: 910 GSITDAP--------KSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
Query: 179 SSQPYLP-PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQ 237
+ P P+QP SQ PP + AP S ++ ++ P ++ +P+
Sbjct: 962 APMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPT---- 1017
Query: 238 GHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAP 281
+++ PPP + T Q+ + KS + + P
Sbjct: 1018 -VKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 35.0 bits (79), Expect = 0.79
Identities = 45/188 (23%), Positives = 58/188 (30%), Gaps = 42/188 (22%)
Query: 1468 EQKEQLQKMKDFGSEPQMADHLPPQESR----LQNTSSRPGMYPPP----GSYRPP-PPM 1518
+Q E+++ +P PQ LQ +SRP S +P P
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301
Query: 1519 GKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP----PPLPPPPPVIKPQTSAVEQERW 1574
KPP P PPA+ P P PP P PL P +KP
Sbjct: 302 SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP--------- 352
Query: 1575 DEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPP----PGPVPMGMPPM 1630
+ ++ A P P PP S P PGP + PP
Sbjct: 353 ----------------VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
Query: 1631 SKPPPVQQ 1638
P QQ
Sbjct: 397 VGKTPAQQ 404
Score = 34.7 bits (78), Expect = 1.0
Identities = 32/106 (30%), Positives = 42/106 (39%), Gaps = 22/106 (20%)
Query: 1482 EPQMADHLPPQESRLQNTSSRPGMYPP----PGSYRPPP-------PMGKPPGSIVRPSA 1530
+P A P Q + S +PG P PG +P P P + PGS +PSA
Sbjct: 483 QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS-AKPSA 541
Query: 1531 ---PPARSSVPVTRPPV-------PIPPPPPPPPLPPPPPVIKPQT 1566
PA+ S + PV P+ PP P PP P+T
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587
Score = 34.3 bits (77), Expect = 1.4
Identities = 17/42 (40%), Positives = 22/42 (52%), Gaps = 1/42 (2%)
Query: 1595 FKSETAAIPSAPVLPPPPVHSSIPPPGPV-PMGMPPMSKPPP 1635
F+S + I + P PPPP PPP P P +PP + P P
Sbjct: 2394 FRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKP 2435
Score = 33.9 bits (76), Expect = 1.8
Identities = 26/83 (31%), Positives = 36/83 (43%), Gaps = 9/83 (10%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPAR---SSVPVTRPPVP 1545
+P Q++ TS++ P S P P KPP P+ PP + S+ P ++ P
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGP--AKPPPQQPGPAKPPPQQPGSAKPPSQQPGS 506
Query: 1546 IPPPP----PPPPLPPPPPVIKP 1564
PPP P P P P KP
Sbjct: 507 TKPPPQQPGPAKPSPQQPGSTKP 529
Score = 32.3 bits (72), Expect = 5.1
Identities = 43/197 (21%), Positives = 61/197 (30%), Gaps = 23/197 (11%)
Query: 1501 SRPGMYPPPGSYRPPPPMGK---PPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPP 1557
S PG + P+ K P + + S P +P P P P P +P
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891
Query: 1558 PPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQ-------------GLNSEFKSETAAIPS 1604
P KPQ EQ R + + D Q G + S+ + + S
Sbjct: 892 PQQSPKPQ----EQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 1605 APVLPPPPVHSSIPPP---GPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGER 1661
P P S P P P P PP + I K + P E+
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 1662 ITLRPDPLPERSTFETE 1678
+ + + P ETE
Sbjct: 1008 LEPKAEQAPTVKRTETE 1024
Score = 32.0 bits (71), Expect = 6.7
Identities = 26/98 (26%), Positives = 36/98 (36%), Gaps = 14/98 (14%)
Query: 1481 SEPQMADHLPPQESR-LQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPS--------AP 1531
S PQ P +++ Q+ S P PP + P G P +P AP
Sbjct: 675 SSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAP 734
Query: 1532 PARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAV 1569
P SVP + P+ P P ++KP T V
Sbjct: 735 PKEPSVPSEQDKAPVADDK-----PKQPKMVKPTTDLV 767
Score = 31.6 bits (70), Expect = 8.8
Identities = 48/210 (22%), Positives = 78/210 (37%), Gaps = 25/210 (11%)
Query: 184 LPPAQPSPSQSPPSQSYLAPTPSYSSSSSSS---QSYLSHSQSYLPSSQASPSRPSQGHS 240
+PPA P SP P P+ SSS ++ Q L Q ++A +
Sbjct: 1125 MPPAPSGPKASP------MPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKE 1178
Query: 241 KSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQ-QYWYR 299
+ PP TT Q++ K+K++ Q+ P P+ + P+E++ + +
Sbjct: 1179 TLSMEKIPPMV------TTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK 1232
Query: 300 QHLLSLQQRTKVHLPGHKK-GPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNE 358
+ LL ++ T P KK P PE K ++ E P
Sbjct: 1233 KPLLEEKKPT----PEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEG 1288
Query: 359 EVPPP----LPPEEPQSEDPEEDARLKQLQ 384
+ P LP PQS E+D K ++
Sbjct: 1289 KQPQTKMEGLPSGTPQSLPKEDDKTTKTIK 1318
Score = 31.6 bits (70), Expect = 8.8
Identities = 39/140 (27%), Positives = 52/140 (37%), Gaps = 25/140 (17%)
Query: 172 PSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQAS 231
P P T ++PP + SQ P PT Y+ SS + LP+ QA
Sbjct: 3856 PRTAPQTEFSQFIPPQTQTESQLVP------PTSPYTQYQYSSPA--------LPT-QAP 3900
Query: 232 PSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEP-LESGAKNKSTEQQQAAPEPDPSTMTP 290
S Q H + Q L S Q +P ++ A T Q Q P P PS P
Sbjct: 3901 TSYTQQSHFEQQTLYHQQVSP-------YQTQPTFQAVATMSFTPQVQPTPTPQPSYQLP 3953
Query: 291 QEQQ--QYWYRQHLLSLQQR 308
+ Q RQ L L+ +
Sbjct: 3954 SQMMVIQQKPRQTTLYLEPK 3973
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 95.1 bits (235), Expect = 6e-19
Identities = 102/356 (28%), Positives = 136/356 (38%), Gaps = 46/356 (12%)
Query: 403 QGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLW 462
+GIM +H + + Y+Q I+PP +++Q+L E +
Sbjct: 143 EGIMPRH----RFMSAYEQRIEPP------------------DRRWQYLLMAAEP----Y 176
Query: 463 EEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQ-----EKVNSFQNMKNQYMGNMSMP 517
E P ++ + K W W K Q +LQ EK + ++ G P
Sbjct: 177 ETIAFKVPSREIDKAEGKFWTHWNRETK--QFFLQFHFKMEKPPAPPSLPAGPPGVKRPP 234
Query: 518 PPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPP-P 576
PP + PPLP PP P LP P MPP PA PPG PP +PP P PP P
Sbjct: 235 PPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPG--PPQLPPPAPGVHPPAP 292
Query: 577 GMPPSLSSAGPP-PVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPP-PGIP 634
+ P S PP P + PP+ P P + PP+ S PP PP PP PG+
Sbjct: 293 VVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPT-SGVHPPAPGVHPPAPGVHPPAPGVH 351
Query: 635 PPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTT-YHPPLQSAG 693
PP G+ P PP S+ Q P A P + G PP HP Q+ G
Sbjct: 352 PPA--PGVHPPAPGVH-PPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHP--QAPG 406
Query: 694 PSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPP 749
Q P + P G P P+ +P G +P PP
Sbjct: 407 VHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLR-PPLPSEGPGNIPPPP 461
Score = 68.6 bits (166), Expect = 6e-11
Identities = 77/311 (24%), Positives = 99/311 (31%), Gaps = 55/311 (17%)
Query: 68 HQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPP-PPGPALSYQKQQQYKHQ 126
+++ Q LQ H P P PP +P G G +PPPP M PP P L
Sbjct: 200 NRETKQFFLQFHFKMEKP-PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPP---- 254
Query: 127 MLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP 186
PPG +P+ P PP P PP +PPP P P P
Sbjct: 255 --------PPGGLPL-----PPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGV 301
Query: 187 AQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLA 246
P+P PP+ P P +S + P+ P P H + +
Sbjct: 302 HPPAPGVHPPAPGVHPPAPGVHPPTSG---------VHPPAPGVHPPAPGV-HPPAPGVH 351
Query: 247 PPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQ 306
PP P P P +G ++ AAP P
Sbjct: 352 PPAPGVHP--PAPGVHPPPSAGVHPQAPGVHPAAPAVHP--------------------- 388
Query: 307 QRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVP---PP 363
Q VH P P P+P + P P P + PP P PP
Sbjct: 389 QAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPP 448
Query: 364 LPPEEPQSEDP 374
LP E P + P
Sbjct: 449 LPSEGPGNIPP 459
Score = 60.5 bits (145), Expect = 2e-08
Identities = 53/149 (35%), Positives = 63/149 (42%), Gaps = 23/149 (15%)
Query: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVP-IPPP-----PPPPPLP 1556
PG++PP PP P PP S V P AP P PP P + PP PP P +
Sbjct: 306 PGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVH 365
Query: 1557 PPP--------PVIKPQTSAVE-QERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAP- 1606
PPP P + P AV Q G+ G++ + PSAP
Sbjct: 366 PPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHP--QAPGVHPQ---PPGVHPSAPG 420
Query: 1607 VLPPPP-VHSSIPPPGPVPMGMPPMSKPP 1634
V P PP VH S P P P MPPM +PP
Sbjct: 421 VHPQPPGVHPSNPGVHP-PTPMPPMLRPP 448
Score = 58.5 bits (140), Expect = 7e-08
Identities = 69/264 (26%), Positives = 84/264 (31%), Gaps = 60/264 (22%)
Query: 15 PPPPVP------PPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68
PPPP+ PP P +LP PG P P+ SG
Sbjct: 233 PPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPG---------------- 276
Query: 69 QKQMQCVLQPHHLPPPP---LPPPPVMPGGGYGDWQPPPPPMPPPPG---PALSYQKQQQ 122
P LPPP PP PV+ G P P PP PG PA
Sbjct: 277 ---------PPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTS 327
Query: 123 YKHQMLHHQRDGPPGLVPMELESPPESP---PVPPGSYMPPSQSYMPP------------ 167
H PG+ P P +P P PG + PPS P
Sbjct: 328 GVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVH 387
Query: 168 PQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPS 227
PQ P + P P P P P PS + P P S+ H + +P
Sbjct: 388 PQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPG----VHPPTPMP- 442
Query: 228 SQASPSRPSQGHSKSQLLAPPPPS 251
P PS+G + PPPP+
Sbjct: 443 PMLRPPLPSEGPGN---IPPPPPT 463
Score = 53.5 bits (127), Expect = 2e-06
Identities = 52/147 (35%), Positives = 58/147 (39%), Gaps = 26/147 (17%)
Query: 517 PPPFV--PYSQMPPPLPTMPPP---VLPPSL----PPPVMPPALPATVPPP--------- 558
P P V P S + PP P + PP V PP+ P P + P P PPP
Sbjct: 318 PAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAP 377
Query: 559 GMPP--PVMPPSLPTSVPP-PGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAP 615
G+ P P + P P PP PGM P P P PS P P PS P
Sbjct: 378 GVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHP 437
Query: 616 PPVMP---LPPLSSATPPPGIPPPGVP 639
P MP PPL S P G PP P
Sbjct: 438 PTPMPPMLRPPLPSEGP--GNIPPPPP 462
Score = 48.9 bits (115), Expect = 5e-05
Identities = 25/65 (38%), Positives = 28/65 (43%), Gaps = 7/65 (10%)
Query: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPP-------PL 1555
PGM+P P PP P V P P S P PP P+PP PP +
Sbjct: 398 PGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNI 457
Query: 1556 PPPPP 1560
PPPPP
Sbjct: 458 PPPPP 462
Score = 48.1 bits (113), Expect = 9e-05
Identities = 42/140 (30%), Positives = 51/140 (36%), Gaps = 33/140 (23%)
Query: 1508 PPGSYRPPPPM--GKPPGSIVRPSAPPAR-SSVPVTRPPVPIPPPPP-----PPPLPPPP 1559
PPG RPPPP+ G PP + S PP +P+ PP+P P P PP LPPP
Sbjct: 227 PPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPL--PPMPPTGPAPSGPPGPPQLPPPA 284
Query: 1560 PVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPP-----PVH 1614
P + P V + P AP + PP P
Sbjct: 285 PGVHPPAPVVHPP------------------ASGVHPPAPGVHPPAPGVHPPAPGVHPPT 326
Query: 1615 SSIPPPGPVPMGMPPMSKPP 1634
S + PP P P PP
Sbjct: 327 SGVHPPAPGVHPPAPGVHPP 346
Score = 45.1 bits (105), Expect = 8e-04
Identities = 45/165 (27%), Positives = 54/165 (32%), Gaps = 43/165 (26%)
Query: 1483 PQMADHLPPQESRLQNTSSRP--GMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVT 1540
P + + LPP+ ++ P G+ PP P P G P + P AP PV
Sbjct: 235 PPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVV 294
Query: 1541 RPPVPIPPPPPPPPLP------PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSE 1594
PP PP P P PP P + P TS V
Sbjct: 295 HPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHP----------------------- 331
Query: 1595 FKSETAAIPSAPVLPPPP-VHSSIP---PPGPVPMGMPPMSKPPP 1635
P+ V PP P VH P PP P P PPP
Sbjct: 332 --------PAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP 368
Score = 39.3 bits (90), Expect = 0.042
Identities = 50/186 (26%), Positives = 61/186 (32%), Gaps = 60/186 (32%)
Query: 13 HYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
H P P V PP P P P PG P + G +H
Sbjct: 330 HPPAPGVHPPAPGVHP---PAPGVHPPAPGVHPPAPG-----------------VH---- 365
Query: 73 QCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPP------PPGPALSYQKQQQYKHQ 126
PPP P PG P P + P PP P + Q
Sbjct: 366 ---------PPPSAGVHPQAPG-----VHPAAPAVHPQAPGVHPPAPGMHPQAPG----- 406
Query: 127 MLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQ--PYL 184
+H Q PPG+ P S P P PPG + P + PP PP PP S+ +
Sbjct: 407 -VHPQ---PPGVHP----SAPGVHPQPPGVH-PSNPGVHPPTPMPPMLRPPLPSEGPGNI 457
Query: 185 PPAQPS 190
PP P+
Sbjct: 458 PPPPPT 463
Score = 39.3 bits (90), Expect = 0.042
Identities = 23/75 (30%), Positives = 28/75 (37%), Gaps = 10/75 (13%)
Query: 1503 PGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP---------- 1552
PG++P + P P PP + P AP P P P P PP
Sbjct: 377 PGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVH 436
Query: 1553 PPLPPPPPVIKPQTS 1567
PP P PP + P S
Sbjct: 437 PPTPMPPMLRPPLPS 451
Score = 38.1 bits (87), Expect = 0.094
Identities = 35/110 (31%), Positives = 38/110 (34%), Gaps = 28/110 (25%)
Query: 1531 PPARSSVPVTRPPVPIPPPPPP---PPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTND 1587
PPA S+P P V PPPP PP PP P + P
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPG------------------- 257
Query: 1588 EQGLNSEFKSETAAIPSAPVLPP--PPVHSSIPPPGPVPMGMPPMSKPPP 1635
GL T PS P PP PP + PP PV PP S P
Sbjct: 258 --GLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVV--HPPASGVHP 303
Score = 37.7 bits (86), Expect = 0.12
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 11/68 (16%)
Query: 1576 EDSFYGLWDTNDEQG-LNSEFKSETA-AIPSAPV------LPPPPVHSSIPPPGPVPMGM 1627
E F+ W+ +Q L FK E A PS P PPPP+ + +PP P+P +
Sbjct: 192 EGKFWTHWNRETKQFFLQFHFKMEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESL 251
Query: 1628 PPMSKPPP 1635
PP PPP
Sbjct: 252 PP---PPP 256
Score = 35.0 bits (79), Expect = 0.79
Identities = 20/51 (39%), Positives = 24/51 (47%), Gaps = 5/51 (9%)
Query: 1501 SRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPP 1551
S PG++P P P P PP P P R +P + P IPPPPP
Sbjct: 417 SAPGVHPQPPGVHPSNPGVHPP----TPMPPMLRPPLP-SEGPGNIPPPPP 462
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 94.4 bits (233), Expect = 1e-18
Identities = 75/196 (38%), Positives = 87/196 (44%), Gaps = 40/196 (20%)
Query: 517 PPPFVPYSQMPPPLPTMPPPVLPPSLP-------PPVMPPA------LPATVPP-PGMPP 562
P P VP PPP P PPP LPP LP P V PP LP PP P PP
Sbjct: 167 PRPNVPAP--PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP 224
Query: 563 PVMPPSLPTSVPPPGMPPS--LSSAGPPPVLPPPSLSSAGPP-PVLPP------------ 607
P PP PT PP +PP+ LS P L P L PP P+LPP
Sbjct: 225 PPPPPPPPT---PPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPAS 281
Query: 608 PSLSSTAPP-PVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKP 666
P+ + PP P PLPP +S +P +P P +P T P+PP S S + P+K
Sbjct: 282 PAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAP-PQKA 340
Query: 667 RPALLPTPVSFGSAPP 682
LP P APP
Sbjct: 341 GAQALPAP----PAPP 352
Score = 93.2 bits (230), Expect = 2e-18
Identities = 90/271 (33%), Positives = 108/271 (39%), Gaps = 62/271 (22%)
Query: 522 PYSQMPPP-LP--TMPPPVLPPS----------------LPPPVMPPALPATVPPPGMPP 562
P S+ P P LP T+ P++PP+ PP PA P PPP PP
Sbjct: 126 PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPP--PP 183
Query: 563 PVMPPSLPTSVP---PPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVM 619
P +PP LP+S P P PP + G PV+ PP + PPP PPP+ PPP+
Sbjct: 184 PPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT-----PPPLP 238
Query: 620 PLPPLSSATPPPGIPP---PGVPQGIP-------PQLTAAPVPPASSSQSSQVPEKPRP- 668
P LS P + P P +P +P P L A P PA +Q P P P
Sbjct: 239 PASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPP 298
Query: 669 -------ALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLG 721
A LP P G + PPL PS Q AP K+ Q L
Sbjct: 299 YASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQ----APPQKAGA--------QALP 346
Query: 722 ESSAAP-SQPITAVK--DMPVRSGGLLPDPP 749
A P SQP K P GG L PP
Sbjct: 347 APPAPPGSQPFLQKKRHGRPGAGGGKLNPPP 377
Score = 85.9 bits (211), Expect = 4e-16
Identities = 86/292 (29%), Positives = 105/292 (35%), Gaps = 82/292 (28%)
Query: 15 PPPPVPPPPPVALPEASPG--PGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
PPPP PPPPP LP P P + +P P + G +
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNL--------------------- 212
Query: 73 QCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQR 132
P PP P PPP PPPPP PPP P S + K
Sbjct: 213 -----PVVAPPVPCAPPP----------PPPPPPPTPPPLPPASVLSDKAVK-------- 249
Query: 133 DGPPGLVPMELES-PPESPPVPPGSY-------MPPSQSYMPPPQPPPSYYPPTSSQPYL 184
P L P+ L PP P +PP Y P+Q PP PPP PY
Sbjct: 250 ---PQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPL------PPY- 299
Query: 185 PPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQL 244
A SP S P+ P P +SSS + S PS QA P K+
Sbjct: 300 --ASCSPRASLPA----PPLPGVNSSSETPPPLPPKS----PSFQAPP-------QKAGA 342
Query: 245 LAPPPPSAPPGNKTTVQQEPL-ESGAKNKSTEQQQAAPEPDPSTMTPQEQQQ 295
A P P APPG++ +Q++ GA A P P+T + QQ
Sbjct: 343 QALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQ 394
Score = 79.7 bits (195), Expect = 3e-14
Identities = 77/250 (30%), Positives = 97/250 (38%), Gaps = 63/250 (25%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPP-------PVMPPALPATVPPPGMPPPV 564
GN+ + P VP + PPP P PPP PP LPP V P P +PP P P+
Sbjct: 210 GNLPVVAPPVPCA--PPPPPPPPPPT-PPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPL 266
Query: 565 MPP-------SLPTS---------VPPPGMPPSLSSAGPPPVLPPPSL----SSAGPPPV 604
+PP + P S PPP +PP +S P LP P L SS+ PP
Sbjct: 267 LPPCGYPGLKAEPASPAQDAQEPPAPPPPLPP-YASCSPRASLPAPPLPGVNSSSETPPP 325
Query: 605 LPPPSLSSTAPPPVMPLPPLSSATPPPGIPP------PGVPQGIPPQLTAAPVPPASSSQ 658
LPP S S APP L + PPG P G P +L P PPA S
Sbjct: 326 LPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPA-RSP 384
Query: 659 SSQVPEKPRPALLPTPV-------------------------SFGSAPPTTYHPPLQSAG 693
++++ K + A TP S PP + P Q
Sbjct: 385 TTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIY 444
Query: 694 PSEQVNSKAP 703
PS+ S+ P
Sbjct: 445 PSKIPRSRTP 454
Score = 76.3 bits (186), Expect = 3e-13
Identities = 59/214 (27%), Positives = 81/214 (37%), Gaps = 57/214 (26%)
Query: 1489 LPPQESRLQNTSS----------RPGMYPPPGSYRPPPPMGKPPG---------SIVRPS 1529
+PP RL NTS RP + PP PPPP PP +V P
Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204
Query: 1530 APPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQ 1589
P + ++PV PPVP PPPPPPP PP PP + P + ++
Sbjct: 205 GPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDK------------------ 246
Query: 1590 GLNSEFKSETAAIPSAPVLPPPPVHSSIPPPG----------PVPMGMPPMSKPPPVQQT 1639
K + A + P+ PP P+ +PP G P P + PPP+
Sbjct: 247 ----AVKPQLAPLHLPPIPPPLPL---LPPCGYPGLKAEPASPAQDAQEPPAPPPPLP-- 297
Query: 1640 VDYGHGRDISTNKVEQIPYGERITLRPDPLPERS 1673
Y ++ +P + P PLP +S
Sbjct: 298 -PYASCSPRASLPAPPLPGVNSSSETPPPLPPKS 330
Score = 65.9 bits (159), Expect = 4e-10
Identities = 110/474 (23%), Positives = 150/474 (31%), Gaps = 104/474 (21%)
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPAT-----VPPPG--------- 559
M +PPP PPPLP PPP+ P PPP PP T P G
Sbjct: 1 MPVPPP------PPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQ 54
Query: 560 -------------MPPPVMPPSLPTSVPPPG--------MPPSLSS--AGPPPVLPPPSL 596
P + S T+ G PP+L AG PVL P
Sbjct: 55 QGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQ 114
Query: 597 ------------SSAGPPPVLPPPSLSSTAPPPVMP--------------LPPLSSA-TP 629
S P P LP ++S PP P PP + P
Sbjct: 115 RDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAP 174
Query: 630 PPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPL 689
PP PPP P PP +++P+ S + + P + P PV PP PP
Sbjct: 175 PPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAP-PVPCAPPPPPPPPPPT 233
Query: 690 QSAGPSEQVNSK-------APLSKSALPYS-SFSSDQGLGESSAAPSQPITAVKDMPVRS 741
P V S APL +P G A P+ P ++ P
Sbjct: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPA-- 291
Query: 742 GGLLPDPPRSSYLE-SPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGH 800
P PP Y SPR P + S E P P P+ P ++
Sbjct: 292 ----PPPPLPPYASCSPRASLPAPP--LPGVNSSSETPPPLPPK---------SPSFQAP 336
Query: 801 PAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLS 860
P + P P SQ ++ P G + P PA +S LS
Sbjct: 337 PQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK-LNPPPA------PPARSPTTELS 389
Query: 861 GNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEV 914
+ + QQ ++++ + I D + S E+ + P ++
Sbjct: 390 SKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKI 443
Score = 59.3 bits (142), Expect = 4e-08
Identities = 85/348 (24%), Positives = 112/348 (32%), Gaps = 84/348 (24%)
Query: 15 PPPPVPPP------PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68
PPPP+PPP PP P A P +SS A P + Q +L+++ Q++
Sbjct: 7 PPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQIN 66
Query: 69 QKQMQCVLQPHHL--------------PPPPLPP------PPVMPGG-----------GY 97
+ + PP L P + P G G
Sbjct: 67 DRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGP 126
Query: 98 GDWQPPP--------PPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPES 149
G P P P+ PP P L + R PP P PP +
Sbjct: 127 GSRAPSPRLPNKTISGPLIPPASPRLGNTSEAH------GAARTAPPR--PNVPAPPPPT 178
Query: 150 PPVPPGSYMPPSQSYMP-------PPQP-----PPSYYPPTSSQPYLPPAQPSPSQSPPS 197
PP PP PP S P PP P P PP P PP P P +PP
Sbjct: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAP--PPPPPPPPPTPPP 236
Query: 198 QSYLAPTPSYSSSSSSSQSYLSHSQSY-----------LPSSQASPSRPSQGHSKSQLLA 246
L P S + Q H P +A P+ P+Q +
Sbjct: 237 ---LPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP 293
Query: 247 PP-PPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQ 293
PP PP A + ++ PL N S+E P PS P ++
Sbjct: 294 PPLPPYASCSPRASLPAPPLP--GVNSSSETPPPLPPKSPSFQAPPQK 339
Score = 57.8 bits (138), Expect = 1e-07
Identities = 87/371 (23%), Positives = 124/371 (33%), Gaps = 84/371 (22%)
Query: 81 LPPPPLPPPPVMPGGGYGDWQPPP---PPMPPPPGPALS--------------------Y 117
+P PP PPPP+ P PPP PP PPP P +S
Sbjct: 1 MPVPPPPPPPLPP-------PPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADI 53
Query: 118 QKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMP----------P 167
Q+ + + + R P ++ES + GS S P P
Sbjct: 54 QQGTRLRKVTQINDRSAP------QIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFP 107
Query: 168 PQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAP--TPSYSSSSSSSQSYLSHSQSYL 225
P + P +PS P+++ P P+ ++S+++
Sbjct: 108 VLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAH-------- 159
Query: 226 PSSQASPSRPSQGHSKSQLLAPPPPSAPPG-NKTTVQQEPLES--GAKNKSTEQQQA--- 279
+++ +P RP+ PPPP PP ++ + PL S G K A
Sbjct: 160 GAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPV 219
Query: 280 ----APEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHL---------------PGHKKGP 320
P P P TP Q +HL PG K P
Sbjct: 220 PCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP 279
Query: 321 V-VAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPN--EEVPPPLPPEEPQSEDPEED 377
A+D EP +P + S PPLP N E PPPLPP+ P + P +
Sbjct: 280 ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK 339
Query: 378 ARLKQLQAAAA 388
A + L A A
Sbjct: 340 AGAQALPAPPA 350
Score = 56.2 bits (134), Expect = 3e-07
Identities = 72/286 (25%), Positives = 91/286 (31%), Gaps = 103/286 (36%)
Query: 82 PPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPM 141
P P PPPP P PPPPP+PPP P+ S K + + P P+
Sbjct: 169 PNVPAPPPPTPP--------PPPPPLPPPL-PSSSPIKTPLVSPPGPLTKGNLPVVAPPV 219
Query: 142 ELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYL 201
PP PP PP PPP PP S + +P L P P PP L
Sbjct: 220 PCAPPPPPPPPPP----------TPPPLPPASVLSDKAVKPQLAPLHLPPI--PPPLPLL 267
Query: 202 APTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQ 261
P P +A P+ P+Q + APPPP P
Sbjct: 268 PPCG-------------------YPGLKAEPASPAQDAQEPP--APPPPLPP-------- 298
Query: 262 QEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPV 321
A+ P S P LPG
Sbjct: 299 ----------------YASCSPRASLPAPP---------------------LPGVNS--- 318
Query: 322 VAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVP-PPLPP 366
+ +TP P+ P+SPS + PP + +P PP PP
Sbjct: 319 -SSETPPPLP-----------PKSPSFQAPPQKAGAQALPAPPAPP 352
Score = 42.0 bits (97), Expect = 0.006
Identities = 16/26 (61%), Positives = 17/26 (65%)
Query: 1542 PPVPIPPPPPPPPLPPPPPVIKPQTS 1567
PP P+PPPPPP PPPPP P S
Sbjct: 7 PPPPLPPPPPPLGAPPPPPPSAPPVS 32
Score = 40.0 bits (92), Expect = 0.025
Identities = 14/21 (66%), Positives = 17/21 (80%)
Query: 1544 VPIPPPPPPPPLPPPPPVIKP 1564
+P+PPPPPPP PPPPP+ P
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAP 21
Score = 37.0 bits (84), Expect = 0.21
Identities = 16/36 (44%), Positives = 21/36 (58%), Gaps = 2/36 (5%)
Query: 1538 PVTRPPVPIPPPP--PPPPLPPPPPVIKPQTSAVEQ 1571
P PP+P PPPP PPP PP P + TS++ +
Sbjct: 5 PPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRR 40
Score = 35.4 bits (80), Expect = 0.61
Identities = 33/110 (30%), Positives = 39/110 (35%), Gaps = 21/110 (19%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP 1542
P LPP S L + + +P + P PPP PP A PA + P
Sbjct: 231 PPTPPPLPPA-SVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEP 289
Query: 1543 PVPIPPPPP-----------PPPLP---------PPPPVIKPQTSAVEQE 1572
P P PP PP PPLP PP P P A Q+
Sbjct: 290 PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQK 339
Score = 33.1 bits (74), Expect = 3.0
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 2/39 (5%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVP 1545
PPP PPPP+G PP PSAPP + R P
Sbjct: 7 PPPPLPPPPPPLGAPPPP--PPSAPPVSTDTSSLRRADP 43
Score = 33.1 bits (74), Expect = 3.0
Identities = 56/239 (23%), Positives = 74/239 (30%), Gaps = 62/239 (25%)
Query: 1476 MKDFGSEPQMAD-HLPPQESRLQ--NTSSRPGMYPPPGSYR--------PPPPMG----- 1519
+ D +PQ+A HLPP L PG+ P S PPPP+
Sbjct: 243 LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASC 302
Query: 1520 KPPGSIVRPSAPPARSSVPVTRPPVP-----------------IPPPPPPPPL------- 1555
P S+ P P SS T PP+P +P PP PP
Sbjct: 303 SPRASLPAPPLPGVNSSSE-TPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKK 361
Query: 1556 --------------PPPPPVIKPQTSAVEQER----WDEDSFYGLWDTNDEQGLNSEFKS 1597
PP PP P T + + W G N + +F+S
Sbjct: 362 RHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFES 421
Query: 1598 ETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQI 1656
+ S PPP + P P +P P P Q G D + Q+
Sbjct: 422 K-FTFHSVEDFPPPDEYK--PCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDIKGRNSQV 477
Score = 32.7 bits (73), Expect = 3.9
Identities = 18/33 (54%), Positives = 20/33 (60%), Gaps = 5/33 (15%)
Query: 1606 PVLPPPPVHSSIPPPGPVPMGMPPMSKP--PPV 1636
PV PPPP +PPP P P+G PP P PPV
Sbjct: 2 PVPPPPP--PPLPPPPP-PLGAPPPPPPSAPPV 31
Score = 32.7 bits (73), Expect = 3.9
Identities = 19/51 (37%), Positives = 22/51 (43%), Gaps = 25/51 (49%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPP--PPL 1555
PPP PPPP+ PP PP+ PPPPPP PP+
Sbjct: 4 PPP----PPPPLPPPP-------------------PPLGAPPPPPPSAPPV 31
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 94.0 bits (232), Expect = 1e-18
Identities = 69/208 (33%), Positives = 85/208 (40%), Gaps = 58/208 (27%)
Query: 519 PFVPYSQMPPPLPTMPPPV---LPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPP 575
P ++ PPP P+ P PV L LPPP MPP P + PPP PP +PP +P ++PP
Sbjct: 207 PHQLFADAPPP-PSAPNPVVSSLGSGLPPPGMPP--PGSFPPPVPPPGALPPGIPPAMPP 263
Query: 576 PGMPPSLSSAGPPPV----------------------LPPPSLS---------------- 597
P MPP + GPP +P P +S
Sbjct: 264 PPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPH 323
Query: 598 -----SAGPPPVLPPPSLSSTAPPPV-MPL--PPLSSATPPPGIPPPGVPQGIPPQL--- 646
S G PP PPP + PPP+ MP PP S PG PP +G PP +
Sbjct: 324 AGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPH 383
Query: 647 --TAAPVPPASSSQSSQVPEKPRPALLP 672
T P PP Q +P PRP P
Sbjct: 384 GYTGPPRPPPYGYQRGPLP-PPRPTPRP 410
Score = 82.8 bits (203), Expect = 3e-15
Identities = 62/187 (33%), Positives = 74/187 (39%), Gaps = 47/187 (25%)
Query: 511 MGNMSMPPPFVPYSQMPPPLPTMP--PPVLPPSLPPPVMPPALPATVPP----PGMPPPV 564
+G+ PP P PPP+P PP +PP++PPP MPP PP PG P
Sbjct: 228 LGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPG 287
Query: 565 MPPSLPTSVPPPGMP-PSLS---------------------SAGPPPVLPPPSLSSAGPP 602
S P PP GMP P +S S G PP PPP + GPP
Sbjct: 288 HGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPP 347
Query: 603 PV-LPP---------------PSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQL 646
P+ +PP P PPP+M P T PP PP G +G P
Sbjct: 348 PMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLM---PPHGYTGPPRPPPYGYQRGPLPPP 404
Query: 647 TAAPVPP 653
P PP
Sbjct: 405 RPTPRPP 411
Score = 65.9 bits (159), Expect = 4e-10
Identities = 63/209 (30%), Positives = 71/209 (33%), Gaps = 48/209 (22%)
Query: 16 PPPVPPP-----------PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQL 64
PPPVPPP PP +P + G G S+ TP A G H
Sbjct: 244 PPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGA----GHPGHGHSHPHPFPPG 299
Query: 65 QQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYK 124
H Q +Q H P L P P G G P PPP P PGP
Sbjct: 300 GMPHPGMSQ--MQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPP---------- 347
Query: 125 HQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPP-QPPPSYYPPTSSQPY 183
P G+ P PP P+ MPP PPP PP Y P PY
Sbjct: 348 ----------PMGMPP---RGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPY 394
Query: 184 ------LPPAQPSPSQS-PPSQSYLAPTP 205
LPP +P+P PP P P
Sbjct: 395 GYQRGPLPPPRPTPRPPVPPRGPLRGPLP 423
Score = 58.5 bits (140), Expect = 7e-08
Identities = 79/302 (26%), Positives = 94/302 (31%), Gaps = 99/302 (32%)
Query: 77 QPHHL----PPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQR 132
+PH L PPPP P PV+ G G PPP MP
Sbjct: 206 RPHQLFADAPPPPSAPNPVVSSLGSG---LPPPGMP------------------------ 238
Query: 133 DGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPS 192
PPG P PPVPP +PP +PP PPP P + + PP+ +P
Sbjct: 239 --PPGSFP---------PPVPPPGALPPG---IPPAMPPPPM--PPGAAGHGPPSAGTPG 282
Query: 193 QSPPSQSYLAP---TPSYSSSSSSSQSYLSHSQSY-LPSSQASPSRPSQGHSKSQLLAPP 248
P + P P SQ L+H + L A P P G P
Sbjct: 283 AGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGP--PGSG-------GQP 333
Query: 249 PPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQR 308
PP PPG P P P M P R
Sbjct: 334 PPRPPPG----------------------MPHPGPPPMGMPP--------RGPPFGSPMG 363
Query: 309 TKVHLPGH-KKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPE 367
+P H +GP P T P P + PLPPP PP+PP
Sbjct: 364 HPGPMPPHGMRGP-----PPLMPPHGYTGPPR---PPPYGYQRGPLPPPRPTPRPPVPPR 415
Query: 368 EP 369
P
Sbjct: 416 GP 417
Score = 56.6 bits (135), Expect = 3e-07
Identities = 60/195 (30%), Positives = 73/195 (37%), Gaps = 49/195 (25%)
Query: 1457 LKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPP 1516
L AAQ ++ QL F P P S L + PGM PPPGS+ PP
Sbjct: 194 LLAAQNPLSQADRPHQL-----FADAPPPPSAPNPVVSSLGSGLPPPGM-PPPGSFPPPV 247
Query: 1517 PMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP-----PPPPPLP-------------PP 1558
P PPG++ P PPA PP P+PP PP P P
Sbjct: 248 P---PPGALP-PGIPPAM-------PPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPF 296
Query: 1559 PPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIP 1618
PP P + Q + +GL + A P + PPP +P
Sbjct: 297 PPGGMPHPG-MSQMQLAHHGPHGLGHPH-------------AGPPGSGGQPPPRPPPGMP 342
Query: 1619 PPGPVPMGMPPMSKP 1633
PGP PMGMPP P
Sbjct: 343 HPGPPPMGMPPRGPP 357
Score = 49.7 bits (117), Expect = 3e-05
Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 5/76 (6%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548
+PP+ + PG PP G PPP M PP P PP R P+P P
Sbjct: 351 MPPRGPPFGSPMGHPGPMPPHGMRGPPPLM--PPHGYTGPPRPPPYG---YQRGPLPPPR 405
Query: 1549 PPPPPPLPPPPPVIKP 1564
P P PP+PP P+ P
Sbjct: 406 PTPRPPVPPRGPLRGP 421
Score = 47.0 bits (110), Expect = 2e-04
Identities = 59/246 (23%), Positives = 74/246 (30%), Gaps = 78/246 (31%)
Query: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS 194
PP P + S S PPG MPP S+ PPP PPP PP +PPA P P
Sbjct: 216 PPPSAPNPVVSSLGSGLPPPG--MPPPGSF-PPPVPPPGALPPG-----IPPAMPPPPMP 267
Query: 195 PPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLL------APP 248
P + + P+ + + SH + P P G S+ QL
Sbjct: 268 PGAAGHGPPSAGTPGAGHPGHGH-SHPHPFPPGGMPHP-----GMSQMQLAHHGPHGLGH 321
Query: 249 PPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQR 308
P + PPG SG Q P P P
Sbjct: 322 PHAGPPG-----------SGG--------QPPPRPPPGM--------------------- 341
Query: 309 TKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEE 368
P P + +P SP P+PP PPPL P
Sbjct: 342 ------------------PHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPH 383
Query: 369 PQSEDP 374
+ P
Sbjct: 384 GYTGPP 389
Score = 45.4 bits (106), Expect = 6e-04
Identities = 37/109 (33%), Positives = 45/109 (41%), Gaps = 24/109 (22%)
Query: 1481 SEPQMADHLPP----QESRLQNTSSRPGMYPPPGSYRP-PPPMGKPP-----GSIVR--- 1527
S+ Q+A H P + + +P PPPG P PPPMG PP GS +
Sbjct: 307 SQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPG 366
Query: 1528 PSAPPARSSVPVTRPP-----VPIPPP------PPPPPLPPPPPVIKPQ 1565
P P P PP P PPP P PPP P P P + P+
Sbjct: 367 PMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPR 415
Score = 38.5 bits (88), Expect = 0.072
Identities = 19/54 (35%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 1592 NSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHG 1645
N S + +P + PP +PPPG +P G+PP PPP+ GHG
Sbjct: 222 NPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGA-AGHG 274
Score = 38.1 bits (87), Expect = 0.094
Identities = 32/110 (29%), Positives = 38/110 (34%), Gaps = 30/110 (27%)
Query: 10 GSSHYPPPPVPP------PPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQ 63
GS PPP PP PPP+ +P GP + S P M
Sbjct: 328 GSGGQPPPRPPPGMPHPGPPPMGMPPR--GPPFGSPMGHPGPMPPHGM------------ 373
Query: 64 LQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGP 113
+ ++ PH PP PPP G PPP P P PP P
Sbjct: 374 ------RGPPPLMPPHGYTGPPRPPPYGYQRGPL----PPPRPTPRPPVP 413
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 93.6 bits (231), Expect = 2e-18
Identities = 106/362 (29%), Positives = 129/362 (35%), Gaps = 61/362 (16%)
Query: 518 PPFVPYSQMP-----PPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTS 572
P +P S P PP T P P P+ P P P PA PP P P
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986
Query: 573 VPPPGMPPSLSSAGP----------PPVLPPPSLSSAGPPPVLPPPSLSSTAP------- 615
PP PPS GP PP + PP S G P P P +ST P
Sbjct: 987 TPPAATPPS-PKGGPATPSPKGAPTPPAVTPP--SPKGSPAATPFPKGASTPPAATPPSP 1043
Query: 616 ---PPVMPLPPLSSATPPPGIP-PPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALL 671
P PLP + TP +P P G P P L AP PPA++ S K PA
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGP--ATPSLKGAPTPPAATPPS----PKGGPA-- 1095
Query: 672 PTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPI 731
TP G+ P PP G + + AP + +A P S +G + P
Sbjct: 1096 -TPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP----PSPKGGLATPPPKGAPT 1150
Query: 732 TAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKG-PRFEGNRP 790
T P GGL PP+ +P P P L + P PKG P P
Sbjct: 1151 TPAATPPSPKGGLATPPPKG----APTTPAATPPSPKGGLAT----PSPKGAPTTPAATP 1202
Query: 791 DGPR-----PRYEGHP----AEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPK 841
P+ P +G P A K G+ P +T SP+ GP PK
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK-GGPATPPPK 1261
Query: 842 PA 843
A
Sbjct: 1262 GA 1263
Score = 91.7 bits (226), Expect = 7e-18
Identities = 108/376 (28%), Positives = 131/376 (34%), Gaps = 58/376 (15%)
Query: 528 PPLPTMPPPVLPPSLPPPVMPPALPATVPP-----PGMPPPVMPPSLPTSVPP-----PG 577
PP T P P P+ P P P PA PP P P P P+ P PP P
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 578 MPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATP-------P 630
P A PP PP S G P P P + T P +P P ATP P
Sbjct: 1025 ATPFPKGASTPPAATPP--SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP 1082
Query: 631 PGIPPPGVPQGIP--PQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPP 688
P PP P+G P P AP+PPA++ P P+ L TP G+ PP
Sbjct: 1083 PAATPPS-PKGGPATPSPKGAPMPPAAT------PPSPKGG-LATPPHKGAPTTPAATPP 1134
Query: 689 LQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDP 748
G + AP + +A P S +G + P T P GGL
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATP----PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 749 PRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKG-PRFEGNRPDGPR-----PRYEGHP- 801
P+ +P P P L + P PKG P P P+ P +G P
Sbjct: 1191 PKG----APTTPAATPPSPKGGLAT----PSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 802 ---AEGTKSKWGMIPRGPASQFYITPSTSLSPRQSG----PQWKG-PKPAFGQQHQQQPK 853
A K G P P + TP + P G P KG P PA +
Sbjct: 1243 TPAATPPSPKGG--PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 854 SQAEPLSGNKEPLADT 869
P G P A T
Sbjct: 1301 PATSPPKGAPTPPAAT 1316
Score = 89.7 bits (221), Expect = 3e-17
Identities = 132/513 (25%), Positives = 170/513 (33%), Gaps = 106/513 (20%)
Query: 512 GNMSMPPP----FVPYSQMPPP---LPTMPP---PVLPPSLPP----------PVMPPAL 551
G ++ PPP P + P P L T P P P + PP P P
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220
Query: 552 PATVPPP-----GMPPPVMPPSLPTSVPP-----PGMPPSLSSAGPPPVLPPPSL----- 596
PA PP P P P+ P + PP P PP A PP PPSL
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP-KGAPTPPAATPPSLKGGLA 1279
Query: 597 ----SSAGPPPVLPPPSLS---STAPPPVMPLPPLSSATPP-----PGIPP----PGVPQ 640
A P V+ PPS +T+PP P PP +ATPP PG PP P P
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP--AATPPSPKGSPGTPPPKGAPTPPA 1337
Query: 641 GIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTP----VSFGSAPPTTYHPPLQSAGPSE 696
PP P PA++ S P P PTP S P T PP GP+
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT--PPSPKRGPAI 1395
Query: 697 QVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLES 756
P S + +P S AP+ P+T G L PP + +
Sbjct: 1396 PSPKGDPTSPAVIPLS----------PKKAPATPVTREGAATPSKGDL--TPPAVTPVSL 1443
Query: 757 PRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGP 816
+ P P+ GP + + P P P+ P
Sbjct: 1444 KKAPATSAPK---------GGPATPSSKGDPTLPAVTPPS----------------PKEP 1478
Query: 817 ASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQK- 875
+ + S+S + P G P PK S ++P+A T++ K
Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMG-APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 876 ---NFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGP-VEPSNWDQNVQSM 931
+ A A V K + ++ P E S P V PS +
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 932 ETQIDKAQAVTQPVPLANKPVPAQSTFPSKTGG 964
E I AVT P P P P T PS G
Sbjct: 1598 ELLI--PPAVTSPSP-KEAPTPPAVTPPSPEKG 1627
Score = 87.0 bits (214), Expect = 2e-16
Identities = 109/398 (27%), Positives = 135/398 (33%), Gaps = 75/398 (18%)
Query: 494 SYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMP-------------PPLPTMPPPV--L 538
S+L E SFQ K+ S PP + P PP T P V L
Sbjct: 834 SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL 893
Query: 539 P-----PSLPPPVMPPALP----------ATVPPPGMPPPVMPPSLPTSVPPPGMPPSLS 583
P P+ P P PAL AT P G+P P PT PP PPS
Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT--PPAATPPS-P 950
Query: 584 SAGP----------PPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATP---- 629
GP PP PPS P P P + T P P P ATP
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGG---PATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007
Query: 630 ---PPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPR--PALLPTPVSFGSAPPTT 684
PP + PP P+G P A P P +S+ + P P+ PA P P + P T
Sbjct: 1008 APTPPAVTPPS-PKGSP---AATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT 1063
Query: 685 YHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGL 744
P GP+ AP +A P S +G + + P+ P GGL
Sbjct: 1064 L--PSPKGGPATPSLKGAPTPPAATP----PSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117
Query: 745 LPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKG-PRFEGNRPDGPRPRYEGHPAE 803
P + +P P P L + P PKG P P P+ P +
Sbjct: 1118 ATPPHKG----APTTPAATPPSPKGGLAT----PPPKGAPTTPAATPPSPKGGLATPPPK 1169
Query: 804 GTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPK 841
G + P P TPS +P PK
Sbjct: 1170 GAPTTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPK 1206
Score = 84.3 bits (207), Expect = 1e-15
Identities = 118/478 (24%), Positives = 179/478 (37%), Gaps = 64/478 (13%)
Query: 519 PFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPP-PG 577
P P S+ P LP + PP P P P + P P P+ P+LP +P P
Sbjct: 1456 PATPSSKGDPTLPAVTPPS-PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514
Query: 578 MPPSLSSAGPPPVLPPPSLSSAGPPPVLPP------PSLSSTAPP--PVMPLPPLSSATP 629
P+ S+ P+ P +L S P L P P+++ +P P +P P + ATP
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574
Query: 630 -------PPGIPPP---GVPQG----IPPQLTA-----APVPPASSSQSSQVPEK--PRP 668
PP + P G P IPP +T+ AP PPA + S PEK P
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS---PEKGPATP 1631
Query: 669 ALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPS 728
A TP S P + P A + ++ + P + LP L E AP+
Sbjct: 1632 APKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK--GPTALKEVLVAPA 1689
Query: 729 QPITAVKDMPVRSGG-----------LLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEG 777
T + P R G + PDP + + P P L + +
Sbjct: 1690 PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPL----LPVQKDS 1745
Query: 778 PRPKGPRFEGNRPDGPRPRYEGHPAEG-TKSKWGMIPRGPASQFYITPSTSLSPRQSGPQ 836
+ + + P GP E + T + + + P S + S + SP S P
Sbjct: 1746 SKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA---SVSAAPSPPVSLPL 1802
Query: 837 WKGPKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQ------QKNFKMQSAAFSIAADV 890
P P + Q P S L +PLA ++ + S+ ++
Sbjct: 1803 APSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNM 1862
Query: 891 KDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPVPLA 948
K+A ++Q P ++ ++G S+ D++V +E Q D QA TQ LA
Sbjct: 1863 PTPKSAGIPVPTPSAKQ--PVTKNNKGSGTESDSDESVPELEEQ-DSTQATTQQAQLA 1917
Score = 79.3 bits (194), Expect = 4e-14
Identities = 90/379 (23%), Positives = 128/379 (33%), Gaps = 54/379 (14%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSS---TTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
PP V PP P P A+P P +S+ TP +P S + + K
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 73 QCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPP---PPGPALSYQKQQQYKHQMLH 129
P PP PP P GG P PMPP PP P H
Sbjct: 1071 PATPSLKGAPTPPAATPP-SPKGGPATPSPKGAPMPPAATPPSPKGGLATPP-------H 1122
Query: 130 HQRDGPPGLVPMELES-----PPESPPVPPGSYMPPSQSYM--PPPQPPPSYYPPTSSQP 182
P P + PP+ P P + P + + PPP+ P+ T P
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 183 YLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPS-QGHSK 241
A PSP +P + + P+P ++ S + + + PS + + PS +G
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 242 SQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAP----EPDPSTMTPQEQQQYW 297
+ PP P P + P A S + A P P+P+ +TP
Sbjct: 1243 TPAATPPSPKGGPATPPP-KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP------- 1294
Query: 298 YRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLP--- 354
P K GP + P T P+ P +P + P P
Sbjct: 1295 ----------------PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV 1338
Query: 355 -PPNEEVPPPLPPEEPQSE 372
PP+ + P LP P S+
Sbjct: 1339 TPPSPKGTPTLPATTPSSK 1357
Score = 78.6 bits (192), Expect = 6e-14
Identities = 126/549 (22%), Positives = 176/549 (32%), Gaps = 123/549 (22%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPT 571
G + PP P PP T P P P PPP P PA PP P +P + P+
Sbjct: 1300 GPATSPPKGAP----TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 572 SVPPPGMPPSLSSAGPP---------PVLPPPSLSSAGP-----------PPVLP----- 606
S P P S PP P + PPS GP P V+P
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS-PKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Query: 607 ------------PPSLSSTAPPPVMPL-----------------------PPLSSATPPP 631
PS PP V P+ P L + TPP
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474
Query: 632 GIPPPGVPQ----GIPPQLTAAPVP----------PASSSQSSQVPEKPRPALLPTPVSF 677
PP Q P + A P P P+S + P R + PT
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL 1534
Query: 678 GSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPY-SSFSSDQGLGESSAAPSQPITAVKD 736
P T P P+ V S P A+P + E+S+ P+ + K
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPS--PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592
Query: 737 MPVRSGGLLPDPPRS-SYLESPRGPRFDGPRRFEDLGSRCEGPRPKG-----PRFEGNRP 790
P L+P S S E+P P P + + P PKG P +
Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT----PAPKGTPTSPPVTPSSLK 1648
Query: 791 DGPRPRYEGHPAEGTKSKWGMIP---------RGPAS--QFYITPSTSLSPRQSGPQWKG 839
D P PA T +P +GP + + + P+ +P + P KG
Sbjct: 1649 DSPT-----SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKG 1703
Query: 840 PKPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSN 899
P Q KS A +P A S + + + D +
Sbjct: 1704 P---------QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA 1754
Query: 900 ENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMET-QIDKAQAVTQPVPLANKPVPA---- 954
+ PP+S+ S P+ + +++ + E+ + A + +PLA PVP
Sbjct: 1755 SHSPKGPLAPPESKAST-PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPK 1813
Query: 955 QSTFPSKTG 963
Q PS G
Sbjct: 1814 QQFLPSSPG 1822
Score = 76.6 bits (187), Expect = 2e-13
Identities = 100/411 (24%), Positives = 130/411 (31%), Gaps = 71/411 (17%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
PP P P V LP GP TP AP + +S + + K +
Sbjct: 881 PPKETPTPSVVNLPFPKEGP-----ATP-APKQAPALSMTSSSPKKARATPA--PKGIPA 932
Query: 75 VLQPHHLPPPPLPPPPVMPGG---GYGDWQPPPPPMPPPP---GPALSYQKQQQYKHQML 128
P P PP PP GG W P PP PP GPA K
Sbjct: 933 SPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992
Query: 129 HHQRDG------------PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYP 176
G PP + P + P + P P G+ PP+ + P P+ P+ P
Sbjct: 993 PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT-PPSPKGSPAATP 1051
Query: 177 PTSSQPYLPPAQ-PSPSQSPPSQSYL-APTPSYSSSSSSSQSYLSHSQSYLP-SSQASPS 233
P P A PSP P + S APTP ++ S + S P A+P
Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Query: 234 RPSQG------------------HSKSQLLAPPP----------PSAPPGNKTTVQQE-- 263
P G K L PPP P +P G T +
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171
Query: 264 PLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVA 323
P A S + A P P + TP + + P K P
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPP----------SPKGGLATPSPKGAPTTP 1221
Query: 324 KDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374
TP K + P+ P +P++ PP P PPP P + P
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAA-TPPSPKGGPATPPPKGAPTPPAATP 1271
Score = 75.1 bits (183), Expect = 7e-13
Identities = 119/507 (23%), Positives = 166/507 (32%), Gaps = 70/507 (13%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPP-----GMPPPVMP 566
G ++ PPP P T P P + PPP P PA PP P P
Sbjct: 1138 GGLATPPP---KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA 1194
Query: 567 PSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPP----VLPPPSLSSTAPPPVMPLP 622
P+ P + PP P A P P P + ++ P P P P + T P P P
Sbjct: 1195 PTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1251
Query: 623 PLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPP 682
ATPP P G AP PPA++ S + L TP G+ P
Sbjct: 1252 KGGPATPP----PKG-----------APTPPAATPPSLK-------GGLATPPHKGAPNP 1289
Query: 683 TTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPIT------AVKD 736
PP GP+ AP +A P S S G AP+ P
Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS-PGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 737 MPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPK-GPRFEGNRPDGPRP 795
+P + P S E P P + G P PK GP + D P
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKG---GPAMTPPSPKRGPAIPSPKGDPTSP 1405
Query: 796 RY-----EGHPAEGTKSKWGMIP-RGPASQFYITP-STSLSPRQSGPQWKGPKPAFGQQH 848
+ PA + P +G + +TP S +P S P+ GP
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK-GGP-------- 1456
Query: 849 QQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQE 908
P S+ +P P + K S+ A + A + S +E
Sbjct: 1457 -ATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515
Query: 909 PPKSEVS-EGPVEPSNWDQNVQSMETQIDK----AQAVTQPVPLANKPVPAQSTFPSKTG 963
P + S P+ P+ + ++ T K A+T P P +P P+
Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS 1575
Query: 964 GMEGGTAVATSSLTADNDFKPVGIGLP 990
E + A + T P + +P
Sbjct: 1576 SKEASSPPAVTPSTYKGAPSPKELLIP 1602
Score = 75.1 bits (183), Expect = 7e-13
Identities = 89/382 (23%), Positives = 132/382 (34%), Gaps = 85/382 (22%)
Query: 10 GSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69
GS PPP P PP P + G +TTP++ S +E
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP--------- 1372
Query: 70 KQMQCVLQPHHLPPPPLPPP-----PVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ---Q 121
P H P + PP P +P P P+ P PA ++
Sbjct: 1373 -----AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 122 QYKHQMLHHQRDGPPGLVPMELE-----SPPESPPVPPGSYMPPSQSYMPPP---QPPPS 173
K + PP + P+ L+ S P+ P P S P+ + PP +PP
Sbjct: 1428 PSKGDLT------PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481
Query: 174 YYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS 233
TSS P PA P+P +P + + +P ++ SS+ P++
Sbjct: 1482 KQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR-----RDPIAPTATLLSK 1536
Query: 234 RPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQ 293
+ + + L PP + P KT P E+ A S+++ + P PST
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA-TPSSKEASSPPAVTPSTY----- 1590
Query: 294 QQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPL 353
K P P KE + PA + SPS +E P
Sbjct: 1591 ------------------------------KGAPSP-KELLIPPAVT----SPSPKEAPT 1615
Query: 354 PPPNEEVPPPLPPEEPQSEDPE 375
PP V PP P + P + P+
Sbjct: 1616 PP---AVTPPSPEKGPATPAPK 1634
Score = 71.6 bits (174), Expect = 8e-12
Identities = 89/392 (22%), Positives = 124/392 (31%), Gaps = 61/392 (15%)
Query: 15 PPPPVPPPPPVALPE------ASPGPGYSSSTTPAAPSS--SGFMSFREQHLAQLQQLQQ 66
PPP P P A P A+P P + +T A P S G + +
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225
Query: 67 MHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQ 126
K P P P PP GG P PP P
Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGG--------PATPPPKGAPT------------ 1265
Query: 127 MLHHQRDGPPGLVPMELE----SPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQP 182
PP P L+ +PP P PPS P PP P ++ P
Sbjct: 1266 --------PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317
Query: 183 YLP---PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRP--SQ 237
P P P P +P + P+P + + + + S PSS+ P+ P +
Sbjct: 1318 PSPKGSPGTPPPKGAPTPPAVTPPSPK-GTPTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376
Query: 238 GHSKSQLLAPPPPS------APPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQ 291
H + PP P +P G+ T+ PL + ++ A P +TP
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPP 1436
Query: 292 EQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEP 351
++ + + P K P + TP KE PA QV S S ++
Sbjct: 1437 AVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP---PAPKQVATSSSPKKA 1493
Query: 352 PLPPPNEEVP------PPLPPEEPQSEDPEED 377
P P P P P E P + D
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Score = 70.5 bits (171), Expect = 2e-11
Identities = 98/404 (24%), Positives = 132/404 (32%), Gaps = 78/404 (19%)
Query: 15 PPPPVPPPPPVALPEASPG-----PGYSSSTTPAA--PSSSGFMSFREQHLAQLQQLQQM 67
PPP P P A P + G P + TTPAA PS G ++ A
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202
Query: 68 HQ-KQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPP-----PPPMPPPP--GPALSYQK 119
K P P P PP P GG P P PP P GPA K
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPP-SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPK 1261
Query: 120 QQQYKHQMLHHQRDGPPGLVPMELE----SPPESPPVPPGSYMPPSQSYMPPPQPPPSYY 175
PP P L+ +PP P PPS P PP
Sbjct: 1262 GAPT-----------PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP 1310
Query: 176 PPTSSQPYLP---PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASP 232
P ++ P P P P P +P + P+P + + ++ PSS+ P
Sbjct: 1311 TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT----------PSSKGGP 1360
Query: 233 SRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQE 292
+ PS P PP+A P +K P S ++ A P P +P
Sbjct: 1361 TTPSSKEG------PTPPAATPSHKGGPAMTP-------PSPKRGPAIPSPKGDPTSPA- 1406
Query: 293 QQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKD--------TPEPVKEEVTVPATSQVPE 344
++ L + P ++G TP +K+ A P
Sbjct: 1407 ---------VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA 1457
Query: 345 SPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAA 388
+PSS+ P P V PP P E P + + K+ A A
Sbjct: 1458 TPSSKGDPTLPA---VTPPSPKEPPAPKQVATSSSPKKAPATPA 1498
Score = 68.6 bits (166), Expect = 6e-11
Identities = 86/375 (22%), Positives = 131/375 (34%), Gaps = 58/375 (15%)
Query: 10 GSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQ 69
G PPP P PP A P + G G ++ AP+ + +
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKG-GLATPPHKGAPNPA--------------VVTPPSP 1297
Query: 70 KQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLH 129
K P P PP PP P G G PPP P PP K
Sbjct: 1298 KGGPATSPPKGAPTPPAATPP-SPKGSPG--TPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354
Query: 130 HQRDGPPGLVPMELESPPESPPVPPGS-YMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQ 188
+ GP E +PP + P G M P P P P P + P + P
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP---TSPAVIPLS 1411
Query: 189 PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSS-QASPSRP-SQGHSKSQLLA 246
P + + P A TPS + + + +S ++ S+ + P+ P S+G +
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 247 PPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQ 306
PP P PP K A + S ++ A P P + P ++
Sbjct: 1472 PPSPKEPPAPKQV---------ATSSSPKKAPATPAPMGAPTLPA----------VIPSS 1512
Query: 307 QRTKVHLPGHKKGPV------VAKDTPEP-------VKEEVTVPATSQVPESPSSEEPPL 353
+ P ++ P+ ++K TP + +TVP+ + P P+ +E P
Sbjct: 1513 PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572
Query: 354 PPPNEEV--PPPLPP 366
P ++E PP + P
Sbjct: 1573 TPSSKEASSPPAVTP 1587
Score = 67.0 bits (162), Expect = 2e-10
Identities = 89/362 (24%), Positives = 117/362 (32%), Gaps = 65/362 (17%)
Query: 18 PVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQ 77
P PP A P + ++P +P + F+ L K
Sbjct: 803 PQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS--------LSFQGSKDSPATT- 853
Query: 78 PHHLPPPPLP-----PPPVMPGGGYGDWQPPPP-PMP-------PPPGPALSYQKQQQYK 124
H P PP P P V P G PP P P P GPA KQ
Sbjct: 854 --HSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA--- 908
Query: 125 HQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYL 184
P L M SP ++ P +P S S P PP + T P
Sbjct: 909 -----------PAL-SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAA----TPPSPKG 952
Query: 185 PPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQL 244
PA PSP +P + P+P ++ S + + + PS + P+ PS + +
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT-- 1010
Query: 245 LAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPS-TMTPQEQQQYWYRQHLL 303
PP PP K + P GA ST P P S TP +
Sbjct: 1011 ---PPAVTPPSPKGSPAATPFPKGA---STPPAATPPSPKGSPAATPLPK---------- 1054
Query: 304 SLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPP 363
LP K GP P T P+ P +PS + P+PP PP
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP---AATPP 1111
Query: 364 LP 365
P
Sbjct: 1112 SP 1113
Score = 58.5 bits (140), Expect = 7e-08
Identities = 117/501 (23%), Positives = 169/501 (33%), Gaps = 78/501 (15%)
Query: 531 PTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMP----------PSLP--TSVPPPGM 578
P P+L SL P + + P G+ P P L S+ P
Sbjct: 629 PDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNH 688
Query: 579 PPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGV 638
P + P++P S + PV P P + ++ P + + P P +PP G
Sbjct: 689 PVKEGTLTTLPLVPTASENC----PVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT 744
Query: 639 PQGIPP----QLTAAPVPPASSSQSSQVPEKPRPA----------LLPTPVSFG-SAPPT 683
P G T+A P ASS + + A L +P G S P
Sbjct: 745 PPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804
Query: 684 TYHPPLQ--SAGPSEQVNS----KAPLSKSALPYSSFSSDQGLGESSAAPSQPI-TAVKD 736
T PP + SAGP + + +P+ S LP +S S QG +S A P + K
Sbjct: 805 TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF-QGSKDSPATTHSPTPPSPKG 863
Query: 737 MPVRS--------GGLLP--DPPRSSYLESP---RGPRFDGPRRFEDLGSRCEGPR---- 779
P S G LP + P S + P GP P++ L P+
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA 923
Query: 780 ---PKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPR-QSGP 835
PKG P P P+ P T P P+ ++ TP + P + GP
Sbjct: 924 TPAPKG------IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977
Query: 836 QWKGPKPAFGQQHQQQPKSQAEPLS----GNKEPLADTSSNQQKNFKM----QSAAFSIA 887
PK A P + P + G P A T + + + + A+ A
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 888 ADVKDVKAAQSNENLSDSQQEPPKSEVSE---GPVEPSNWDQNVQSMETQIDKAQAVTQP 944
A K + + L P + + GP PS T P
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097
Query: 945 VPLANKPVPAQSTFPSKTGGM 965
P P+P +T PS GG+
Sbjct: 1098 SP-KGAPMPPAATPPSPKGGL 1117
Score = 57.8 bits (138), Expect = 1e-07
Identities = 111/460 (24%), Positives = 156/460 (33%), Gaps = 62/460 (13%)
Query: 529 PLPTMP-PPVLPPSLPPPVMPPA--LPATVPPPGM-------PPPVMPPSLPTSVPPPGM 578
PL T+ P +P S+P P +PPA P T G+ P P PT G
Sbjct: 720 PLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTE--DSGA 777
Query: 579 PPSLSSAGPPPVL---PPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635
+ SS G L P P S P PP S P P+ LSS P
Sbjct: 778 SATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD--TPIGNLSSPVSP----- 830
Query: 636 PGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGS-APPTTYHPPLQSAGP 694
V P+ + + S ++ P P P PTP + +P PP ++ P
Sbjct: 831 --VEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTP 888
Query: 695 SEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVR-SGGLLPDPPRSSY 753
S VN P A P + + SS ++ A K +P S P PP ++
Sbjct: 889 S-VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP 947
Query: 754 LESPRGPRFDGPRRFEDLGSRCEGPRPKG------PRFEGNRPDGPRPRYEGHPAEGTKS 807
GP P ++ P PKG P+ P P +G PA +
Sbjct: 948 PSPKGGPATPSP-KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS-- 1004
Query: 808 KWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLA 867
P+G + +TP SP+ S PK A P + P + PL
Sbjct: 1005 -----PKGAPTPPAVTPP---SPKGSPAATPFPKGASTPPAATPPSPKGSPAA---TPLP 1053
Query: 868 DTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSE--GPVEPSNWD 925
+ A + AA + K + +L + P + S GP PS
Sbjct: 1054 ------------KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101
Query: 926 QNVQSMETQIDKAQAVTQPVPLANKPVPAQSTFPSKTGGM 965
+ T + P P P +T PS GG+
Sbjct: 1102 APMPPAATPPSPKGGLATP-PHKGAPTTPAATPPSPKGGL 1140
Score = 56.2 bits (134), Expect = 3e-07
Identities = 84/369 (22%), Positives = 120/369 (32%), Gaps = 58/369 (15%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
P P P P LP P S PA PSS R +A L K+
Sbjct: 1494 PATPAPMGAPT-LPAVIPS---SPKEVPATPSS------RRDPIAPTATLLS---KKTPA 1540
Query: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDG 134
L P PP P P P P P A + ++
Sbjct: 1541 TLAPKEALIPPAMTVP----------SPKKTPAIPTPKEAPATPSSKE---------ASS 1581
Query: 135 PPGLVPMELESPPESPP--VPPGSYMP-PSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSP 191
PP + P + P +PP P P ++ PP PPS P PA P+P
Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPS--------PEKGPATPAP 1633
Query: 192 SQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPS 251
+P S + P+ S +S + + +S+ P++ K L+AP P S
Sbjct: 1634 KGTPTSPP-VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPES 1692
Query: 252 APPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKV 311
P + P G + K + PDPS + L Q+
Sbjct: 1693 TP------IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746
Query: 312 HLPGHKKGPVVAKDTPEPVKEEVTVPATSQV-------PESPSSEEPPLPPPNEEV-PPP 363
K K P + + + P T+ PES S P PP + + P P
Sbjct: 1747 KTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP 1806
Query: 364 LPPEEPQSE 372
+P P+ +
Sbjct: 1807 VPTLPPKQQ 1815
Score = 50.1 bits (118), Expect = 2e-05
Identities = 85/376 (22%), Positives = 115/376 (30%), Gaps = 84/376 (22%)
Query: 78 PHHLPPPPLPPPPVMPG----GGYGDWQPPPPPMPPP----------------------- 110
P +P P LPP PG G P P
Sbjct: 731 PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL 790
Query: 111 ---PGPALSYQKQQQYKHQMLHHQRDGPPGLV--------PMELESPPES---------- 149
P P L Q K GP + P+E PE+
Sbjct: 791 ADSPSP-LGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849
Query: 150 -----PPVPPGSYMPPSQSYMPPPQPP----PSYYPPTSSQPYLP-----PAQPSPSQSP 195
P PP P+ S + P P P PT S LP PA P+P Q+P
Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909
Query: 196 --------PSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAP 247
P ++ P P +S S + + + PS + P+ PS + + A
Sbjct: 910 ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 248 PPPSAPPGNKTTVQQE--PLESGAKNKSTEQQQAAPE----PDPSTMTPQEQQQYWYRQH 301
PP +P G T + P A S + A P P P +TP +
Sbjct: 970 PP--SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP 1027
Query: 302 LLSLQQRTKVHLPGHKKGPVVAKDTPE--PVKEEVTVPATSQVPESPSSEEPPLPPPNEE 359
P KG A P+ P T+P+ P +PS + P PP
Sbjct: 1028 FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP---A 1084
Query: 360 VPPPLPPEEPQSEDPE 375
PP P P + P+
Sbjct: 1085 ATPPSPKGGPATPSPK 1100
Score = 49.3 bits (116), Expect = 4e-05
Identities = 98/429 (22%), Positives = 154/429 (35%), Gaps = 70/429 (16%)
Query: 17 PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQL-----QQMHQKQ 71
P V P P +P A+P SS P AP+++ LA + L K+
Sbjct: 1506 PAVIPSSPKEVP-ATP----SSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560
Query: 72 MQCVLQPHHLPPPPLP-----PPPVMPGGGYGDWQPP----------PPPMPPPPGPALS 116
+ P P P PP V P G P P P P PA++
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Query: 117 YQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPP---VPPGSYMPPSQSYMPPPQPPPS 173
++ P + P L+ P SP G+ +P + +P + P +
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680
Query: 174 YY-----PPTSSQPYL-------PPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHS 221
P S P + P + S + SPP + P PS + S S ++ +
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP----ICPDPSAKNGSKGPLSTVAPA 1736
Query: 222 QSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQ--- 278
L Q S+ ++G S +P P APP +K + PL + A K + +
Sbjct: 1737 P--LLPVQKDSSKTAKGKDASH--SPKGPLAPPESKAST---PLTAAAFEKVLPKPESAS 1789
Query: 279 --AAPEPDPS---------TMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTP 327
AAP P S T+ P+ QQ+ L L+ +K P + ++ P
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPK--QQFLPSSPGLVLESPSKPLAPADED-ELLPLIPP 1846
Query: 328 EPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPL--PPEEPQSEDPEEDARLKQLQA 385
EP+ V + +P S P+P P+ + P +S+ E L++ +
Sbjct: 1847 EPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDS 1906
Query: 386 AAAHWQQHQ 394
A QQ Q
Sbjct: 1907 TQATTQQAQ 1915
Score = 48.1 bits (113), Expect = 9e-05
Identities = 65/272 (23%), Positives = 95/272 (34%), Gaps = 40/272 (14%)
Query: 521 VPYSQMPPPLPTMPPPVLP---------------PSLPPPVMPPALPATVPPPGMPPPVM 565
VP ++ P P VLP P+LPPP P + P
Sbjct: 9 VPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFP 68
Query: 566 PPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPP--PSLSSTAPPPVMP--- 620
PS S P P SS P+ P + P + PP P+ + A P + P
Sbjct: 69 SPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLK 128
Query: 621 -LPPLSSATPPPGIPPPGVPQ--GIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF 677
P S+ + P V + PP L +P P + ++S V L P++
Sbjct: 129 GTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP-PSVAVAESGSV------ITLSAPIA- 180
Query: 678 GSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL--GESSAAPSQPITA-- 733
S P T + P+ + P S +PY + + G +S + P T
Sbjct: 181 PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLA 240
Query: 734 -----VKDMPVRSGGLLPDPPRSSYLESPRGP 760
VKD + S + P P S L+ P P
Sbjct: 241 IASPQVKDTTISSVLISPQNPGSLSLKGPVSP 272
Score = 46.2 bits (108), Expect = 3e-04
Identities = 76/322 (23%), Positives = 102/322 (31%), Gaps = 65/322 (20%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSS----------------------SGFMSF 53
PP V PP P P A+P P + ++ P PSS S +
Sbjct: 1616 PPAVTPPSPEKGP-ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674
Query: 54 REQHLAQLQQLQQMHQKQMQCVLQPHHLPP---------PPLPPPPVMPGGGYGDWQPPP 104
++ A + L + + P P PP+ P P G G
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG------ 1728
Query: 105 PPMPPPPGPALSYQKQQQY--KHQMLHHQRDGPPGLVPMELESPPESPPVPPGSY----- 157
P P P L QK K + H GP L P E ++ S P+ ++
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP--LAPPESKA---STPLTAAAFEKVLP 1783
Query: 158 MPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSY 217
P S S P PP S S P L PP Q +L +P S S
Sbjct: 1784 KPESASVSAAPSPPVSLPLAPSPVPTL----------PPKQQFLPSSPGLVLESPSKPLA 1833
Query: 218 LSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSA-----PPGNKTTVQQEPLESGAKNK 272
+ LP P + P P SA P K V + SG ++
Sbjct: 1834 PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESD 1893
Query: 273 STEQQQAAPEPDPSTMTPQEQQ 294
S E E D + T Q+ Q
Sbjct: 1894 SDESVPELEEQDSTQATTQQAQ 1915
Score = 45.4 bits (106), Expect = 6e-04
Identities = 40/157 (25%), Positives = 55/157 (35%), Gaps = 20/157 (12%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRP 1542
P A LP Q + P P PP P G P S V P +P + P P
Sbjct: 830 PVEASFLPENSLSFQGSKDSPATTHSP---TPPSPKGAPTPSAVTPLSPKGVTLPPKETP 886
Query: 1543 P-----VPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKS 1597
+P P P P P P + +S+ ++ R T +G+ +
Sbjct: 887 TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR----------ATPAPKGIPASPSP 936
Query: 1598 ETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634
+ A P A P P + P P P PP + PP
Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAP--TPPAATPP 971
Score = 44.7 bits (104), Expect = 0.001
Identities = 50/188 (26%), Positives = 66/188 (35%), Gaps = 42/188 (22%)
Query: 1491 PQESRLQNTSSRPGMYPPP--GSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPV---- 1544
P S + + P PP GS PPP G P V P +P ++P T P
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360
Query: 1545 --------PIPPPPPP-----PPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGL 1591
P PP P P + PP P P A+ + D S + + ++
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGP---AIPSPKGDPTS-PAVIPLSPKKAP 1416
Query: 1592 NSEFKSETAAIPSAPVLPPPPV---------HSSIPPPGP----------VPMGMPPMSK 1632
+ E AA PS L PP V +S P GP +P PP K
Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPK 1476
Query: 1633 PPPVQQTV 1640
PP + V
Sbjct: 1477 EPPAPKQV 1484
Score = 42.0 bits (97), Expect = 0.006
Identities = 71/270 (26%), Positives = 97/270 (35%), Gaps = 62/270 (22%)
Query: 518 PPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMP------PPVMPPSL-- 569
P + + + P P P P P LP + PP P P++ P+L
Sbjct: 70 PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKG 129
Query: 570 -PTSVPPPGM----PPSL--SSAGPPPVL-PPPSLSSAG--------------------- 600
P+S P + P S+ SSA PP +L PPS++ A
Sbjct: 130 TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLN 189
Query: 601 --PPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP--PGVPQGIPPQLTAAPVPPASS 656
P V+P P + +PP ++ P TP I +PQ P A P
Sbjct: 190 KVPSEVVPNPK-GTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKD 248
Query: 657 SQSSQV---PEKPRPALLPTPVSFGSAPPTTYHPPLQS----------AGPSEQVNSKAP 703
+ S V P+ P L PVS PP QS AGP+ +
Sbjct: 249 TTISSVLISPQNPGSLSLKGPVS----PPAALSLSTQSLPVVTSSQKTAGPNTPPDFPIS 304
Query: 704 LSKSALP--YSSFSSDQGLGESS-AAPSQP 730
L P SSF S Q LG++ +A S P
Sbjct: 305 LGSHLAPLHQSSFGSVQLLGQTGPSALSDP 334
Score = 40.4 bits (93), Expect = 0.019
Identities = 44/155 (28%), Positives = 52/155 (33%), Gaps = 27/155 (17%)
Query: 1500 SSRPGMYPPPGSYRPPPPMGKPP---GSIVRPSAPPARSSVPVTRPPVP----IPPPPPP 1552
S + G+ P P P PP G + PS P + P PP P PPP
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPS-PKGAPTTPAATPPSPKGGPATPPPKG 1262
Query: 1553 PPLPP--PPPVIK------PQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPS 1604
P PP PP +K P A S G T+ +G A P
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG---------APTPP 1313
Query: 1605 APVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639
A P P PPP P PP PP + T
Sbjct: 1314 AATPPSPKGSPGTPPPKGAP--TPPAVTPPSPKGT 1346
Score = 40.0 bits (92), Expect = 0.025
Identities = 42/159 (26%), Positives = 52/159 (32%), Gaps = 31/159 (19%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKP----------PGSIVRPSAPPARSSVP- 1538
PP T S G PP + PP P G P P ++ PS + ++ P
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAA-TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 1539 ---VTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEF 1595
+ PP PP P P P P P T A S G T +G
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL-----PSPKGGPATPSLKG----- 1078
Query: 1596 KSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634
P+ P PP P P MPP + PP
Sbjct: 1079 ------APTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Score = 40.0 bits (92), Expect = 0.025
Identities = 40/165 (24%), Positives = 53/165 (32%), Gaps = 6/165 (3%)
Query: 1477 KDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAP---PA 1533
++ + P D PP + + + P P G P G P V P +P PA
Sbjct: 1422 REGAATPSKGDLTPPAVTPV-SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPA 1480
Query: 1534 RSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNS 1593
V + P P P P P P VI V T + +
Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540
Query: 1594 EFKSETAAIPSAPVLPPPPVHSSIPPP--GPVPMGMPPMSKPPPV 1636
+ A IP A +P P +IP P P S PP V
Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585
Score = 39.7 bits (91), Expect = 0.032
Identities = 71/261 (27%), Positives = 97/261 (37%), Gaps = 46/261 (17%)
Query: 521 VPYSQMPPPLPTMPPPVLPPSLPPPVMPP---------ALPATVPPPGMP---PPVMPPS 568
VP +P P T PP + ++P + P +LP T P + P V +
Sbjct: 191 VPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTT 250
Query: 569 LPTSVPPPGMPPSLSSAGPPPVLPPP--SLSSAGPPPVLPPPSLSSTAPPPVMP------ 620
+ + + P P SLS G PV PP SLS+ P V + PP P
Sbjct: 251 ISSVLISPQNPGSLSLKG--PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSH 308
Query: 621 LPPLSSA----------TPPPGIPPPGVPQ-GIPPQLTAAPVPPASSSQSSQVPEKP-RP 668
L PL + T P + P V + T A P SQ S +P P R
Sbjct: 309 LAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYP----SQRSVIPPLPSRN 364
Query: 669 ALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFS---SDQGLGESSA 725
++P V +A P P GPS + S S +SFS + + +SS
Sbjct: 365 EVVPATV---AAFPVV--APSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSP 419
Query: 726 APSQPITAVKDMPVRSGGLLP 746
+ V MPV S G P
Sbjct: 420 NATYHYPLVAQMPVSSVGTTP 440
Score = 38.5 bits (88), Expect = 0.072
Identities = 34/148 (22%), Positives = 46/148 (31%), Gaps = 21/148 (14%)
Query: 1490 PPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPP 1549
PP + ++ P P G PPP G P P +P + P + P
Sbjct: 1120 PPHKGAPTTPAATPPS--PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177
Query: 1550 PPPPP---LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAP 1606
PP P L P P P T A + + GL + P+ P
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAAT-------------PPSPKGGLAT---PSPKGAPTTP 1221
Query: 1607 VLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634
PP + P P P + PP
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPP 1249
Score = 38.5 bits (88), Expect = 0.072
Identities = 38/127 (29%), Positives = 42/127 (33%), Gaps = 16/127 (12%)
Query: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVP--IPPPPPPPPLPPPPPVIKP 1564
P P PP P G P S P + P PP P P PPP P PP V P
Sbjct: 1287 PNPAVVTPPSPKGGP-----ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Query: 1565 QTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPS---APVLPPPPVHSSIPPPG 1621
S G T + E + AA PS P + PP P
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPS----SKEGPTPPAATPSHKGGPAMTPPSPKRG--PAI 1395
Query: 1622 PVPMGMP 1628
P P G P
Sbjct: 1396 PSPKGDP 1402
Score = 38.1 bits (87), Expect = 0.094
Identities = 38/180 (21%), Positives = 62/180 (34%), Gaps = 30/180 (16%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPP---GSIVRPSAPPARSSVPVT-RPPV 1544
LP Q+ + + + P G PP P + + P +SV PPV
Sbjct: 1739 LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPV 1798
Query: 1545 PIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPS 1604
+P P P P PP P + + E + L ++++ L
Sbjct: 1799 SLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKP----LAPADEDELL------------- 1841
Query: 1605 APVLPPPPVHSSIP-------PPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIP 1657
P++PP P+ +P P P G+ P+ P Q G ++ E +P
Sbjct: 1842 -PLIPPEPISGGVPFQSVLVNMPTPKSAGI-PVPTPSAKQPVTKNNKGSGTESDSDESVP 1899
Score = 37.4 bits (85), Expect = 0.16
Identities = 64/265 (24%), Positives = 96/265 (36%), Gaps = 43/265 (16%)
Query: 103 PPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQ 162
P P +PPP PA QQ L P P + S P P P S S
Sbjct: 41 PGPTLPPPCSPA-----PQQCP---LSAANQASPFPSPSTIASTPLEVPFPQSS----SG 88
Query: 163 SYMPPPQPP--PSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSH 220
+ +P P P++ P P SP+ + +APT + SSS+ + ++
Sbjct: 89 TALPLGTAPEAPTFLPNLIGPPI------SPAALALASPMIAPTLKGTPSSSAPLALVAL 142
Query: 221 SQSYLPSSQASP-----SRPSQGHSKS-QLLAPPPPSAPPGNKTTVQQEPLESGAKNKST 274
+ + S A P S PS ++S ++ P AP KT + + P E K T
Sbjct: 143 APHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGT 202
Query: 275 EQQQAAPEPDP-STMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEE 333
P +TP Q + SL Q T P P ++
Sbjct: 203 PSPPCIVSTVPYHCVTPMASIQ----SGVASLPQTT----------PTTTLAIASPQVKD 248
Query: 334 VTVPATSQVPESPS--SEEPPLPPP 356
T+ + P++P S + P+ PP
Sbjct: 249 TTISSVLISPQNPGSLSLKGPVSPP 273
Score = 37.4 bits (85), Expect = 0.16
Identities = 44/159 (27%), Positives = 50/159 (31%), Gaps = 36/159 (22%)
Query: 1490 PPQESRLQNTSSRP----GMYPPPGSYRPPPPMGKPPGSIVRPSAP---PARSSV----- 1537
P Q L TSS P P G P P G P P +P PA S
Sbjct: 905 PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT 964
Query: 1538 -PVTRPPVPIPPPPPPPPL-PPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEF 1595
P PP P P P P P PP P + +G +
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPS---------------------PKGGPATP 1003
Query: 1596 KSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634
+ A P A V PP P S P P PP + PP
Sbjct: 1004 SPKGAPTPPA-VTPPSPKGSPAATPFPKGASTPPAATPP 1041
Score = 37.0 bits (84), Expect = 0.21
Identities = 103/443 (23%), Positives = 147/443 (33%), Gaps = 76/443 (17%)
Query: 563 PVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMP-L 621
P + T V PP +S+ P P +L A P P +++T PV P L
Sbjct: 453 PTTTFEVATCVSPPMSSGPISNIEPTS---PAALVMAPVAPKEPSTQVATTLRIPVSPPL 509
Query: 622 PPLSSATPPPG-----IPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVS 676
P P P Q +P L AP PA + +++ P + P +
Sbjct: 510 PDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKN 569
Query: 677 FGSAPPTTYHP-----------------PLQSAGPSEQVNSKAPLSKSALPYSSFSSDQG 719
S T+ P PL P+ + S ++ SA S +D
Sbjct: 570 SPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSA---SVIKTDSY 626
Query: 720 LGESSAAP---SQPIT-AVKDMPVRS---GGLLPDPPR-SSYLESPRGPRFDGPRRFEDL 771
G SA P S IT V P+ S G+ P + +S + P +G
Sbjct: 627 AGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPK 686
Query: 772 GSRC-EG---PRPKGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTS 827
EG P P N P P P+ P + + P P S PS S
Sbjct: 687 NHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPL----ATLVLAPEIPKS----VPSPS 738
Query: 828 LSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKE-PLADTSSNQQKNFKMQSAAFSI 886
L P + P G K G H + A S KE P D+ ++ + K +
Sbjct: 739 LPPAGTPP---GTKKVDGISH---TSALAPVASSPKECPTEDSGASATASSK---GTLTY 789
Query: 887 AADVKDVKAAQSNENLSDSQQEPPKSEVSEG-------------PVEPSNWDQNVQSMET 933
AD + ++S + PP + S G PVE S +N S +
Sbjct: 790 LAD----SPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQG 845
Query: 934 QIDKAQAVTQPVPLANKPVPAQS 956
D P P + K P S
Sbjct: 846 SKDSPATTHSPTPPSPKGAPTPS 868
Score = 37.0 bits (84), Expect = 0.21
Identities = 35/140 (25%), Positives = 46/140 (32%), Gaps = 28/140 (20%)
Query: 1507 PPPGSYRPPPPMG-----KPPGSIVRPSAPPARSSVPVTRPP---VPIPPPPPPPP---- 1554
P P + PP P G P G+ + P+A P + PP P P PP
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139
Query: 1555 LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVH 1614
L PPP P T A + + GL + P+ P PP
Sbjct: 1140 LATPPPKGAPTTPAAT-------------PPSPKGGLAT---PPPKGAPTTPAATPPSPK 1183
Query: 1615 SSIPPPGPVPMGMPPMSKPP 1634
+ P P P + PP
Sbjct: 1184 GGLATPSPKGAPTTPAATPP 1203
Score = 35.8 bits (81), Expect = 0.46
Identities = 37/140 (26%), Positives = 49/140 (35%), Gaps = 10/140 (7%)
Query: 1504 GMYPPPGSYRPPPPMGKPPGSIV---RPSAPPARSSVPVTRPPVP-IPPPPPPPPLPPPP 1559
G PP + PP P G P + + P+ P A P P P + P PP PP
Sbjct: 1031 GASTPPAA-TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 1560 PVIKPQT----SAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHS 1615
P P T A S G T +G + + T P + PPP +
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT-PAATPPSPKGGLATPPPKGA 1148
Query: 1616 SIPPPGPVPMGMPPMSKPPP 1635
P P ++ PPP
Sbjct: 1149 PTTPAATPPSPKGGLATPPP 1168
Score = 35.8 bits (81), Expect = 0.46
Identities = 38/154 (24%), Positives = 48/154 (31%), Gaps = 35/154 (22%)
Query: 1500 SSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSS--VPVTRPPVP-----IPPP--- 1549
S + G P P PP PP + PP + + P PP P PPP
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 1550 ------PPPPP---LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETA 1600
PP P L PPP P T A + + GL +
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAAT-------------PPSPKGGLAT---PSPK 1192
Query: 1601 AIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPP 1634
P+ P PP + P P P + PP
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226
Score = 35.4 bits (80), Expect = 0.61
Identities = 65/278 (23%), Positives = 90/278 (32%), Gaps = 29/278 (10%)
Query: 81 LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140
LPPP P P P P P P P L Q L P G P
Sbjct: 45 LPPPCSPAPQQCPLSAANQASPFPSPSTIASTP-LEVPFPQSSSGTAL------PLGTAP 97
Query: 141 MELESPPE--SPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQ 198
P PP+ P + S P + PS P + P + S PP
Sbjct: 98 EAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP-- 155
Query: 199 SYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKT 258
+ L PS + + S S L S+ +PS P +K P P P
Sbjct: 156 NLLTSPPSVAVAESGSVITL--------SAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPC 207
Query: 259 TVQQEPLESGAKNKSTEQQQAA-PEPDPST---MTPQEQQQYWYRQHLLSLQQRTKVHLP 314
V P S + A+ P+ P+T + + + L+S Q + L
Sbjct: 208 IVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSL- 266
Query: 315 GHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPP 352
KGPV + + V +SQ P++ PP
Sbjct: 267 ---KGPVSPPAALSLSTQSLPVVTSSQKTAGPNT--PP 299
Score = 34.3 bits (77), Expect = 1.4
Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 33/160 (20%)
Query: 158 MPPSQSYMPPPQPPPSYYPPTSS--------QP---YLPPAQPSPSQSP----------P 196
+P ++ +P PQ + P +S+ QP PP P+P Q P P
Sbjct: 9 VPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFP 68
Query: 197 SQSYLAPTP---SYSSSSSSSQSYLS---HSQSYLPSSQASPSRPSQGHSKSQLLAPPPP 250
S S +A TP + SSS + L + ++LP+ P P+ S ++AP
Sbjct: 69 SPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLK 128
Query: 251 SAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTP 290
P + PL A + Q+ +A P+ T P
Sbjct: 129 GTPSSS------APLALVALAPHSVQKSSAFPPNLLTSPP 162
Score = 34.3 bits (77), Expect = 1.4
Identities = 82/377 (21%), Positives = 122/377 (32%), Gaps = 62/377 (16%)
Query: 18 PVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQ 77
PV PP ++L S SS T + F HLA L HQ V
Sbjct: 269 PVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPL------HQSSFGSVQL 322
Query: 78 PHHLPPPPLPPPPV--------MPGGGYGDWQPPPPPMPP----PPGPALSYQKQQQYKH 125
P L P V G Y + PP+P P ++
Sbjct: 323 LGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAF-------- 374
Query: 126 QMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLP 185
++ D P + SP S V + P+ S + P +Y+ P +Q +
Sbjct: 375 PVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVS 434
Query: 186 PAQPSP-SQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQL 244
+P + P APT ++ ++ +S S P S P+ P+ + +
Sbjct: 435 SVGTTPLVVTNPCTIAAAPTTTFEVATC-----VSPPMSSGPISNIEPTSPA-----ALV 484
Query: 245 LAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTM--TPQEQQQYWYRQHL 302
+AP P P T + P+ + P PDP + P + Q
Sbjct: 485 MAPVAPKEPSTQVATTLRIPV-------------SPPLPDPEDLKNLPSSVLVKFPTQKD 531
Query: 303 LSLQQRTKVHLP--------GHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLP 354
L + P KK P V K + +TS PE P S E L
Sbjct: 532 LQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATL- 590
Query: 355 PPNEEVPPPLPPEEPQS 371
+ + PLP +P S
Sbjct: 591 -AKKSLGEPLPIGKPAS 606
Score = 34.3 bits (77), Expect = 1.4
Identities = 44/170 (25%), Positives = 55/170 (32%), Gaps = 33/170 (19%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPP---------PGSYRP--------PPPMGKPPGSI 1525
P + P + SS+ G PP P P P P G P
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406
Query: 1526 VRPSAPPARSSVPVTRPPVPIPPPP--PPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLW 1583
V P +P + PVTR P PP + P P TSA + G
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK----------GGP 1456
Query: 1584 DTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIP---PPGPVPMGMPPM 1630
T +G + + T P P P SS P P P PMG P +
Sbjct: 1457 ATPSSKG-DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Score = 32.3 bits (72), Expect = 5.1
Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 8/86 (9%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPP---PGSYR--PPPPMGKPPGSIVRPSAPPARSSV 1537
P+ +P + SS+ PP P +Y+ P P P ++ PS P +
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS-PKEAPTP 1616
Query: 1538 PVTRPPVPIPPPPPPPP--LPPPPPV 1561
P PP P P P P P PPV
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPV 1642
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 92.0 bits (227), Expect = 5e-18
Identities = 64/159 (40%), Positives = 68/159 (42%), Gaps = 29/159 (18%)
Query: 515 SMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVM---PPALPATVPPPGMPPPVMPPSLPT 571
S PPP P P P P PP PP PPP++ PP P PG PPP PPS P
Sbjct: 298 SHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFP- 356
Query: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPP 631
P A PPP PPP A P LPPP LS P PP PPP
Sbjct: 357 --------PHPDFAAPPPPPPPP----AADYPTLPPPPLSQ----PTGGAPP-----PPP 395
Query: 632 GIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPAL 670
PPPG P PP T A PA S KP+ +L
Sbjct: 396 PPPPPGPP---PPPFTGADGQPAIPPPLSDT-TKPKSSL 430
Score = 82.8 bits (203), Expect = 3e-15
Identities = 67/232 (28%), Positives = 91/232 (39%), Gaps = 42/232 (18%)
Query: 21 PPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHH 80
PPPP + +SP P +S P P+ + Q+ + + V+ P H
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYP-------VDNQRGSGLAGPKRSSVVSPSH 299
Query: 81 LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140
PPP PP PG G PP PP PPPP + PP P
Sbjct: 300 --PPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGI-------------------PPPPPP 338
Query: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP---AQP---SPSQS 194
+ SP PP P S+ PP + PP PPP PP + P LPP +QP +P
Sbjct: 339 VGFGSPGTPPPPSPPSF-PPHPDFAAPPPPPP---PPAADYPTLPPPPLSQPTGGAPPPP 394
Query: 195 PPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLA 246
PP P P ++ + S + P S S P+ ++S LL+
Sbjct: 395 PPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKS----SLPAVSDARSDLLS 442
Score = 67.8 bits (164), Expect = 1e-10
Identities = 45/115 (39%), Positives = 51/115 (44%), Gaps = 28/115 (24%)
Query: 517 PPPFVPYSQMPPPL----PTMPPPVLPPSLPP------PVMPPALPA----TVPPP---- 558
PPP + PPP+ P PPP PPS PP P PP PA T+PPP
Sbjct: 326 PPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQ 385
Query: 559 ---GMPPPVMPPSLPTSVPPPGMPPS-LSSAGPPPVLPPPSLSSAGPPPVLPPPS 609
G PPP PP PPPG PP + A P +PPP + P LP S
Sbjct: 386 PTGGAPPPPPPP------PPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVS 434
Score = 66.6 bits (161), Expect = 2e-10
Identities = 86/350 (24%), Positives = 122/350 (34%), Gaps = 63/350 (18%)
Query: 401 QYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQ 460
Q Q + +++ +L+ Y PPP L Y ++ Y + F
Sbjct: 106 QDQKLFDRNSLPVPVLETYNTCDTPPPL-------NNLTPYRDDGKEALKFYTDPSYFFD 158
Query: 461 LWEEQLHSYPHKDQLQE---YEKQWKTWQGHMKATQSYLQEKVNSFQNMK--------NQ 509
LW+E++ KD ++E + K+ K ++ + ++ MK +
Sbjct: 159 LWKEKMLQ-DTKDIMKEKRKHRKEKKDNPNRGNVNPRKIKTRKEEWEKMKMGQEFVESKE 217
Query: 510 YMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPG-----MPPPV 564
+G PP V + + + S PPP P + A+ P P +PPP
Sbjct: 218 KLGTSGYPPTLVYQNGSIGCVENVDAS----SYPPP--PQSDSASSPSPSFSEDNLPPPP 271
Query: 565 MPPSLP------TSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPV 618
S P + + P +S + PPP PP S GP P PP P
Sbjct: 272 AEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPA--PPLGSPPGPKPGFAPP-------PAP 322
Query: 619 MPLPPLSSATPP---------PGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPA 669
P PP PP PG PPP P PP A PP ++ P P P
Sbjct: 323 PPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPP- 381
Query: 670 LLPTPVSFGSAPPTTYHPPLQS------AGPSEQVNSKAPLSKSALPYSS 713
P G APP PP G Q PLS + P SS
Sbjct: 382 --PLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSS 429
Score = 66.6 bits (161), Expect = 2e-10
Identities = 40/106 (37%), Positives = 45/106 (42%), Gaps = 30/106 (28%)
Query: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
P PP PPPP + +P P G+ S TP PS F +
Sbjct: 320 PAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD------------------- 360
Query: 75 VLQPHHLPPPP------LPPPPV-MPGGGYGDWQPPPPPMPPPPGP 113
P PPPP LPPPP+ P GG PPPPP PPPPGP
Sbjct: 361 FAAPPPPPPPPAADYPTLPPPPLSQPTGG----APPPPPPPPPPGP 402
Score = 63.2 bits (152), Expect = 3e-09
Identities = 52/161 (32%), Positives = 64/161 (39%), Gaps = 36/161 (22%)
Query: 1490 PPQESRLQNTS---SRPGMYPPPGSYRPPPPMGKPPG-------SIVRPSAPPARSSVPV 1539
PPQ + S S + PPP + P + G S+V PS PP + P+
Sbjct: 249 PPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPP--APPL 306
Query: 1540 TRPPVPIP--PPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKS 1597
PP P P PPP PP PPPPP+I G+ G S
Sbjct: 307 GSPPGPKPGFAPPPAPP-PPPPPMI------------------GIPPPPPPVGFGS---P 344
Query: 1598 ETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQ 1638
T PS P PP P ++ PPP P P P PPP+ Q
Sbjct: 345 GTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQ 385
Score = 62.0 bits (149), Expect = 6e-09
Identities = 47/160 (29%), Positives = 56/160 (35%), Gaps = 48/160 (30%)
Query: 9 GGSSHYPPPPVPPPPP---VALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQ 65
G + PPP PPPPP + +P P G+ S TP PS F +
Sbjct: 311 GPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPD---------- 360
Query: 66 QMHQKQMQCVLQPHHLPPPP------LPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQK 119
P PPPP LPPPP+ G PPPPP P PP P +
Sbjct: 361 ---------FAAPPPPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFT--- 408
Query: 120 QQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMP 159
DG P + PP S P S +P
Sbjct: 409 -----------GADGQPAI------PPPLSDTTKPKSSLP 431
Score = 61.2 bits (147), Expect = 1e-08
Identities = 52/169 (30%), Positives = 57/169 (33%), Gaps = 61/169 (36%)
Query: 1488 HLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIP 1547
H PP +PG PPP PPPPM P P PP P T PP P P
Sbjct: 299 HPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIP-----PPPPPVGFGSPGTPPP-PSP 352
Query: 1548 P----------PPPPPPLP-------PPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQG 1590
P PPPPPP P PPPP+ +P
Sbjct: 353 PSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQP-------------------------- 386
Query: 1591 LNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQT 1639
T P P PPPP PPP G P + PPP+ T
Sbjct: 387 --------TGGAPPPP--PPPPPPGPPPPPFTGADGQPAI--PPPLSDT 423
Score = 42.4 bits (98), Expect = 0.005
Identities = 62/271 (22%), Positives = 85/271 (31%), Gaps = 74/271 (27%)
Query: 161 SQSYMPPPQPPPSYYP-PTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLS 219
+ SY PPPQ + P P+ S+ LPP PP++ SY +
Sbjct: 243 ASSYPPPPQSDSASSPSPSFSEDNLPP--------PPAEF------SYPVDNQRGSGLAG 288
Query: 220 HSQSYLPSSQASPSRPSQGHS---KSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQ 276
+S + S P P G K PP P PP + P G + T
Sbjct: 289 PKRSSVVSPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTP- 347
Query: 277 QQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTV 336
P P P + P H P P + T+
Sbjct: 348 ----PPPSPPSFPP-------------------------HPDFAAPPPPPPPPAADYPTL 378
Query: 337 PATSQVPESPSSEEPPLPPPNEEVPPP----------LPP-----EEPQSEDPE-EDARL 380
P + + PP PPP PPP +PP +P+S P DAR
Sbjct: 379 PPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARS 438
Query: 381 KQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQ 411
L A R GFQ + + ++ Q
Sbjct: 439 DLLSAI----------RQGFQLRRVEEQREQ 459
Score = 33.9 bits (76), Expect = 1.8
Identities = 18/51 (35%), Positives = 21/51 (41%)
Query: 514 MSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPV 564
+S P P PPP P PPP + P +PP L T P P V
Sbjct: 383 LSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPKSSLPAV 433
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 92.0 bits (227), Expect = 5e-18
Identities = 106/379 (27%), Positives = 133/379 (35%), Gaps = 81/379 (21%)
Query: 500 VNSFQNMKNQYMGNMSMPPPFVPYSQMPPPL----PTMPPPVLPPSLP--PPVMPPALPA 553
++S QN+ N+ + P Q P P P PPP PP P PP P
Sbjct: 13 LSSAQNL-NEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPP--PPGKPQGPPPQGGNKPQ 69
Query: 554 TVPPPGMP--PPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLS 611
PPPG P PP + PPG P GPPP G P PPP
Sbjct: 70 GPPPPGKPQGPPPQGDKSRSPRSPPGKPQ-----GPPP--------QGGNQPQGPPP--- 113
Query: 612 STAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALL 671
PP PP P G PPPG PQG PPQ S+ P P
Sbjct: 114 ---PPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQ-----------GDKSRSPRSPPGKPQ 159
Query: 672 PTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPI 731
P G+ P PP + GP Q K + P G+ S + P
Sbjct: 160 GPPPQGGNQPQGPPPPPGKPQGPPPQGGKKP---QGPPPPGKPQGPPPQGDKSRSSQSPP 216
Query: 732 TAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPD 791
+ P + G PP P+GP G G++ +GP P G +P
Sbjct: 217 GKPQGPPPQGGNQPQGPPPPP--GKPQGPPPQG-------GNKPQGPPPPG------KPQ 261
Query: 792 GPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQ- 850
GP P G ++ +S G P+GP P+Q G +GP P G QQ
Sbjct: 262 GP-PAQGGSKSQSARSPPGK-PQGP-------------PQQEGNNPQGPPPPAGGNPQQP 306
Query: 851 ------QPKSQAEPLSGNK 863
QP+ P G +
Sbjct: 307 QAPPAGQPQGPPRPPQGGR 325
Score = 77.4 bits (189), Expect = 1e-13
Identities = 84/329 (25%), Positives = 109/329 (33%), Gaps = 72/329 (21%)
Query: 77 QPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPP 136
+P PPPP P P GG PPPP P P P + + G P
Sbjct: 46 KPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR--------SPPGKP 97
Query: 137 GLVPMELESPPESPPVPPGSYM--------------PPSQSYMPPPQ---------PP-- 171
P + + P+ PP PPG PP + PPPQ PP
Sbjct: 98 QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGK 157
Query: 172 PSYYPPTS-SQPYLPPAQPSPSQSPPSQSYL---APTPSYSSSSSSSQSYLSHSQSYLPS 227
P PP +QP PP P Q PP Q P P Q S S P
Sbjct: 158 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217
Query: 228 SQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPST 287
P P QG ++ Q PPPP P Q P + G K + P P
Sbjct: 218 KPQGP--PPQGGNQPQ--GPPPPPGKP------QGPPPQGGNKPQG-------PPPPGKP 260
Query: 288 MTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPS 347
P Q + ++ PG +GP ++E P P +
Sbjct: 261 QGPPAQG---------GSKSQSARSPPGKPQGPP---------QQEGNNPQGPPPPAGGN 302
Query: 348 SEEPPLPPPNEEVPPPLPPEEPQSEDPEE 376
++P PP + PP PP+ + P +
Sbjct: 303 PQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 76.3 bits (186), Expect = 3e-13
Identities = 81/296 (27%), Positives = 97/296 (32%), Gaps = 42/296 (14%)
Query: 18 PVPPPPPVALPEASPGPGYSSSTTPAAPSS-SGFMSFREQHLAQLQQLQQMHQKQMQCVL 76
P PPPP P+ P G + P P G ++ + + Q
Sbjct: 47 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 106
Query: 77 QPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMP---PPPGPALSYQKQQQYKHQ----MLH 129
QP PPPP P P GG PPPP P PP G + K Q
Sbjct: 107 QPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 166
Query: 130 HQRDGPPGLVPMELESPP-------ESPPVPPGSYMPP-----SQSYMPPPQPPPSYYPP 177
+Q GPP P + + PP + PP P PP S+S PP P P
Sbjct: 167 NQPQGPPP-PPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQ 225
Query: 178 TSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQ 237
+QP PP P Q PP Q P P P+Q
Sbjct: 226 GGNQPQGPPPPPGKPQGPPPQGGNKPQGP-------------------PPPGKPQGPPAQ 266
Query: 238 GHSKSQLLAPPP--PSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQ 291
G SKSQ PP P PP + Q P N Q A +P PQ
Sbjct: 267 GGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ 322
Score = 67.0 bits (162), Expect = 2e-10
Identities = 66/187 (35%), Positives = 71/187 (37%), Gaps = 32/187 (17%)
Query: 518 PPFVPYSQMPPPL----PTMPPPVLPPSLP--PPVMPPALPATVPPPGMP--PPVMPPSL 569
PP P Q PPP P PPP PP P PP P PPPG P PP
Sbjct: 154 PPGKP--QGPPPQGGNQPQGPPP--PPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKS 209
Query: 570 PTSVPPPGMP--PSLSSAGPPPVLPPPSLSSAGPPPVL------PPPSLSSTAPPPVMPL 621
+S PPG P P P PPP GPPP PPP PP
Sbjct: 210 RSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGS 269
Query: 622 PPLSSATPPPGIPPPGVPQGIPPQ---LTAAPVPPASSS-QSSQVPEKPRPALLPTPVSF 677
S+ + PPG PQG P Q P PPA + Q Q P +P P P
Sbjct: 270 KSQSARS------PPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 323
Query: 678 G--SAPP 682
G S PP
Sbjct: 324 GRPSRPP 330
Score = 65.9 bits (159), Expect = 4e-10
Identities = 58/165 (35%), Positives = 60/165 (36%), Gaps = 36/165 (21%)
Query: 517 PPPFVPYSQMPPPL----PTMPPPVLPPSLPPPV--------MPPALPATVPPPGMPPPV 564
PPP P Q PPP P PPP P PPP PP P PP G P
Sbjct: 174 PPPGKP--QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQ 231
Query: 565 MPPSLPTSVPPPGMPPSLS-SAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPP------- 616
PP PPPG P G P PPP GPP S S+ +PP
Sbjct: 232 GPP------PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPP 285
Query: 617 ------PVMPLPPLSSATPPPGIPPPGVPQG--IPPQLTAAPVPP 653
P P PP P PP G PQG PPQ PP
Sbjct: 286 QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
Score = 63.5 bits (153), Expect = 2e-09
Identities = 60/186 (32%), Positives = 66/186 (35%), Gaps = 29/186 (15%)
Query: 9 GGSSHYPPPPV-----PPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQ 63
G PPPP PPP P+ P PG P P G S Q Q
Sbjct: 166 GNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG-----KPQGPPPQGDKSRSSQSPPGKPQ 220
Query: 64 LQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQY 123
Q QP PPPP P P GG PPPP P P PA K Q
Sbjct: 221 -----GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-PAQGGSKSQSA 274
Query: 124 KHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPP---PQPPPSYYPPTSS 180
+ G P P + + P+ PP P G P Q PP PQ PP PP
Sbjct: 275 R------SPPGKPQGPPQQEGNNPQGPPPPAGG--NPQQPQAPPAGQPQGPPR--PPQGG 324
Query: 181 QPYLPP 186
+P PP
Sbjct: 325 RPSRPP 330
Score = 63.2 bits (152), Expect = 3e-09
Identities = 62/179 (34%), Positives = 71/179 (39%), Gaps = 38/179 (21%)
Query: 1480 GSEPQMADHLPPQESRLQNT----SSRPGMYPPPGSYRPPPPMG-------KPPGSIVRP 1528
G++PQ PP + Q +RP PPPG + PPP G PPG P
Sbjct: 105 GNQPQGP---PPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 161
Query: 1529 SAPPARSSVPVTRPPVPIPPPPPPP-----PLPPPPPVIKPQTSAVEQER-WDEDSFYGL 1582
PP + P PP P P PPP P PPPP KPQ + ++ S G
Sbjct: 162 --PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG-KPQGPPPQGDKSRSSQSPPGK 218
Query: 1583 WDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP--GPVPMGMPPMSKP--PPVQ 1637
QG N P P PPPP PPP G P G PP KP PP Q
Sbjct: 219 PQGPPPQGGNQ---------PQGP--PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQ 266
Score = 60.1 bits (144), Expect = 2e-08
Identities = 61/179 (34%), Positives = 71/179 (39%), Gaps = 38/179 (21%)
Query: 1480 GSEPQMADHLPPQESRLQNT----SSRPGMYPPPGSYRPPPPMG-------KPPGSIVRP 1528
G++PQ PP + Q ++P PPPG + PPP G PPG P
Sbjct: 44 GNKPQGP---PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 100
Query: 1529 SAPPARSSVPVTRPPVPIPPPPPPP-----PLPPPPPVIKPQTSAVEQER-WDEDSFYGL 1582
PP + P PP P P PPP P PPPP KPQ + ++ S G
Sbjct: 101 --PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG-KPQGPPPQGDKSRSPRSPPGK 157
Query: 1583 WDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPP--GPVPMGMPPMSKP--PPVQ 1637
QG N P P PPPP PPP G P G PP KP PP Q
Sbjct: 158 PQGPPPQGGNQ---------PQGP--PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ 205
Score = 56.2 bits (134), Expect = 3e-07
Identities = 71/277 (25%), Positives = 93/277 (33%), Gaps = 65/277 (23%)
Query: 115 LSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQS----YMPPPQP 170
L+ Q+ ++ GP + + PP P P G PP Q PPP
Sbjct: 19 LNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQG---PPPQGGNKPQGPPPPG 75
Query: 171 PPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQA 230
P PP + P + P Q PP Q P Q P
Sbjct: 76 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP------------------QGPPPPPGK 117
Query: 231 SPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTP 290
P QG ++ Q PPPP P G P G K++S P+ P P
Sbjct: 118 PQGPPPQGGNRPQ--GPPPPGKPQG--------PPPQGDKSRSPRSPPGKPQGPP----P 163
Query: 291 QEQQQYWYRQHLLSLQQRTKVHLPGHKKGP-----VVAKDTPEPVKEEVTVPATSQVPES 345
Q Q + PG +GP + P P K + P Q +S
Sbjct: 164 QGGN-----------QPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPP---QGDKS 209
Query: 346 PSSEEPP----LPPP---NEEVPPPLPPEEPQSEDPE 375
SS+ PP PPP N+ PP PP +PQ P+
Sbjct: 210 RSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 246
Score = 53.5 bits (127), Expect = 2e-06
Identities = 49/163 (30%), Positives = 62/163 (38%), Gaps = 22/163 (13%)
Query: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMG-------KPPGSIVRPSAPPARSSVPVTRPP 1543
PQ Q + G PPPG + PPP G PPG +P PP + +
Sbjct: 158 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPG---KPQGPPPQGDKSRSSQS 214
Query: 1544 VPIPPPPPPP-----PLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSE 1598
P P PPP P PPPP KPQ + + G QG ++ S+
Sbjct: 215 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ----GPPPPGKPQGPPAQGGSK 270
Query: 1599 TAAIPSAPVLPP-PPVHSSIPPPGPVPM--GMPPMSKPPPVQQ 1638
+ + S P P PP P GP P G P + PP Q
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 313
Score = 47.8 bits (112), Expect = 1e-04
Identities = 56/236 (23%), Positives = 70/236 (29%), Gaps = 80/236 (33%)
Query: 147 PESPPVPPGSYM-PPSQS----YMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYL 201
P+ PP PPG PP Q PPP P PP + P + P Q PP Q
Sbjct: 47 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 106
Query: 202 APTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQ 261
P Q P P QG ++ Q PPPP P G
Sbjct: 107 QP------------------QGPPPPPGKPQGPPPQGGNRPQ--GPPPPGKPQG------ 140
Query: 262 QEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPV 321
P G K++S P+ P PQ Q +GP
Sbjct: 141 --PPPQGDKSRSPRSPPGKPQGPP----PQGGNQ---------------------PQGP- 172
Query: 322 VAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEED 377
P P + P P ++ P PP +PQ P+ D
Sbjct: 173 ---------------------PPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGD 207
Score = 47.0 bits (110), Expect = 2e-04
Identities = 39/124 (31%), Positives = 59/124 (47%), Gaps = 17/124 (13%)
Query: 1077 GSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPP 1136
G++ +G PG + P G + R G + +GPP + G+Q +GP G + + PP
Sbjct: 65 GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG-KPQGPPPQGGNQPQGPPPPPG-KPQGPP 122
Query: 1137 RRAGSRERGP-----PRGP---GSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEP 1188
+ G+R +GP P+GP G + R RS G+ +GP P GG + P P
Sbjct: 123 PQGGNRPQGPPPPGKPQGPPPQGDKSRS-PRSPPGKPQGP----PPQGGNQ--PQGPPPP 175
Query: 1189 PRAP 1192
P P
Sbjct: 176 PGKP 179
Score = 46.2 bits (108), Expect = 3e-04
Identities = 39/134 (29%), Positives = 62/134 (46%), Gaps = 17/134 (12%)
Query: 1077 GSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPP 1136
G+R +G PG + P G + R G + +GPP + G+Q +GP G + + PP
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPG-KPQGPPPQGGNQPQGPPPPPG-KPQGPP 183
Query: 1137 RRAGSRERGP-----PRGP---GSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEP 1188
+ G + +GP P+GP G + R +S G+ +GP P GG + P P
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRS-SQSPPGKPQGP----PPQGGNQ--PQGPPPP 236
Query: 1189 PRAPWNHGEERGHE 1202
P P + G++
Sbjct: 237 PGKPQGPPPQGGNK 250
Score = 45.1 bits (105), Expect = 8e-04
Identities = 38/137 (27%), Positives = 59/137 (43%), Gaps = 23/137 (16%)
Query: 1077 GSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPP 1136
G + +G PG + P G + + G + +GPP + G+Q +GP G + + PP
Sbjct: 187 GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG-KPQGPPPQGGNQPQGPPPPPG-KPQGPP 244
Query: 1137 RRAGSRERGP-----PRGP---GSRERGLGRSDFGRDRGPFR--------PEPGDGGEKM 1180
+ G++ +GP P+GP G + RS G+ +GP + P P GG
Sbjct: 245 PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 304
Query: 1181 YPY-----HRDEPPRAP 1192
P PPR P
Sbjct: 305 QPQAPPAGQPQGPPRPP 321
Score = 42.0 bits (97), Expect = 0.006
Identities = 36/112 (32%), Positives = 41/112 (36%), Gaps = 15/112 (13%)
Query: 512 GNMSMPPPFVP-YSQMPPP----LPTMPPPVLPPSLPPPVMPPALPATVPPPGMP--PPV 564
GN PP P Q PPP P PPP P PP + PPG P PP
Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286
Query: 565 MPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPP 616
+ P PPP + P PP+ GPP PP + PP
Sbjct: 287 QEGNNPQGPPPP------AGGNPQQPQAPPAGQPQGPP--RPPQGGRPSRPP 330
Score = 38.9 bits (89), Expect = 0.055
Identities = 29/99 (29%), Positives = 43/99 (43%), Gaps = 16/99 (16%)
Query: 1094 PGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERI----------PPRRAGSRE 1143
PG QG +G G++ +GPP Q GP + GS+ + PP++ G+
Sbjct: 237 PGKPQGPPPQG--GNKPQGPPPPGKPQ--GPPAQGGSKSQSARSPPGKPQGPPQQEGNNP 292
Query: 1144 RGPPRGPGSRERGLGRSDFGRDRGPFRPEPGDGGEKMYP 1182
+GPP G + G+ +GP P P GG P
Sbjct: 293 QGPPPPAGGNPQQPQAPPAGQPQGP--PRPPQGGRPSRP 329
Score = 37.4 bits (85), Expect = 0.16
Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 6/100 (6%)
Query: 1472 QLQKMKDFGSEPQMADHLPPQE-SRLQNTSSRPGMY---PPPGSYRP--PPPMGKPPGSI 1525
Q K + S P PPQ ++ Q PG PP G +P PPP GKP G
Sbjct: 205 QGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 264
Query: 1526 VRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQ 1565
+ + + P +P P P PPPP PQ
Sbjct: 265 AQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 304
Score = 35.4 bits (80), Expect = 0.61
Identities = 33/100 (33%), Positives = 38/100 (38%), Gaps = 28/100 (28%)
Query: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMG-------KPPGSIVRPSAPPARS---SVPVT 1540
PQ Q + G PPPG + PPP G PPG +P PPA+ S
Sbjct: 219 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPPAQGGSKSQSAR 275
Query: 1541 RPPV------------PIPPPPPP---PPLPPPPPVIKPQ 1565
PP P PPPP P P PP +PQ
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 315
Score = 35.4 bits (80), Expect = 0.61
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Query: 1477 KDFGSEPQMADHLPPQE--SRLQNTSSRPGMYPPPGSYRPPPPMGKPP---GSIVRPSAP 1531
K G P PP + S+ Q+ S PG P P G PP G+ +P AP
Sbjct: 250 KPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP 309
Query: 1532 PARSSVPVTRPPVPIPPPPPP 1552
PA RPP P PP
Sbjct: 310 PAGQPQGPPRPPQGGRPSRPP 330
Score = 35.0 bits (79), Expect = 0.79
Identities = 37/163 (22%), Positives = 62/163 (38%), Gaps = 26/163 (15%)
Query: 1068 SREKMNRGEGSRDRGLVRPGSSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGP--- 1124
S + +N + + G+ + P G Q + +GPP + G++ +GP
Sbjct: 15 SAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP 74
Query: 1125 ---------------LRRAGSRERIPPRRAGSRERGPPRGPGSRERGLGRSDFGRDRGPF 1169
R + + PP + G++ +GPP PG + +G R +GP
Sbjct: 75 GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG-KPQGPPPQGGNRPQGP- 132
Query: 1170 RPEPGDGGEKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAP 1212
P PG + PR+P G+ +G P G N P
Sbjct: 133 -PPPGKPQGPPPQGDKSRSPRSP--PGKPQGP---PPQGGNQP 169
Score = 33.9 bits (76), Expect = 1.8
Identities = 30/113 (26%), Positives = 50/113 (44%), Gaps = 16/113 (14%)
Query: 1088 SSREKVPGGLQGSQDRGAAGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGP- 1146
SS + + + + +GP + G++ +GP G + + PP + G++ +GP
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPG-KPQGPPPQGGNKPQGPP 72
Query: 1147 ----PRGP---GSRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAP 1192
P+GP G + R RS G+ +GP P GG + P PP P
Sbjct: 73 PPGKPQGPPPQGDKSRS-PRSPPGKPQGP----PPQGGNQ--PQGPPPPPGKP 118
Score = 33.9 bits (76), Expect = 1.8
Identities = 30/101 (29%), Positives = 38/101 (37%), Gaps = 29/101 (28%)
Query: 1480 GSEPQMADHLPPQESRLQNT----SSRPGMYPPPGSYRPPPPMG--------KPPGSIVR 1527
G++PQ PP + Q ++P PPPG + PP G PPG +
Sbjct: 227 GNQPQGP---PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG---K 280
Query: 1528 PSAPPARSSVPVTRPPVPI------PPPPPP-----PPLPP 1557
P PP + PP P P PP PP PP
Sbjct: 281 PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 91.7 bits (226), Expect = 7e-18
Identities = 62/167 (37%), Positives = 80/167 (47%), Gaps = 31/167 (18%)
Query: 489 MKATQSYLQ-EKVNSFQNM-KNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPV 546
M T SY+ E S Q+M K + ++PP + P + +P P V PP+ PPP
Sbjct: 432 MSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLP-----YHPHVYPPNPPPPP 486
Query: 547 MPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLP 606
+PP PA+ PPP +PPP PG PP PPP P + PPP LP
Sbjct: 487 VPPP-PASFPPPAIPPPT-----------PGYPP------PPPTYNP---NFPPPPPRLP 525
Query: 607 PPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPP 653
P PPP + LPP S PPP +PP G P +PP + +PP
Sbjct: 526 PTHAVPPHPPPGLGLPPAS--YPPPAVPPGGQPP-VPPPIPPPGMPP 569
Score = 84.3 bits (207), Expect = 1e-15
Identities = 76/228 (33%), Positives = 85/228 (37%), Gaps = 56/228 (24%)
Query: 517 PPPFVPYSQM--PPPLPTMPPPVLPPSL---------PPPVMPPALPAT-VPPPGMPPPV 564
PPP +P + PP P PPP P L P PV LP +PPP P PV
Sbjct: 351 PPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPV 410
Query: 565 -MPPSLPTSVPPPGMPPS------------------------LSSAGPPPVLPPPSLSSA 599
PP LP PPP PPS + + GP PP+
Sbjct: 411 HQPPPLPHRPPPP--PPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAY--- 465
Query: 600 GPPPVLP--PPSLSSTAPPPVMPLPPLSSATPPPGIPP--PGVPQGIPPQLTAAPVPPAS 655
GPP LP P PPP +P PP S PPP IPP PG P P P PP
Sbjct: 466 GPPAHLPYHPHVYPPNPPPPPVPPPPAS--FPPPAIPPPTPGYPPPPPTYNPNFPPPPPR 523
Query: 656 SSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAP 703
+ VP P P L PP +Y PP G V P
Sbjct: 524 LPPTHAVPPHPPPGL--------GLPPASYPPPAVPPGGQPPVPPPIP 563
Score = 69.3 bits (168), Expect = 4e-11
Identities = 66/200 (33%), Positives = 75/200 (37%), Gaps = 55/200 (27%)
Query: 16 PPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC- 74
P PV PPP LP P P SS T + +SS +MS Q LQ M + +
Sbjct: 407 PAPVHQPPP--LPHRPPPPPPSSYMTGMSTTSS-YMSGEGY-----QSLQSMMKTEGPSY 458
Query: 75 -VLQPHHLPPPPLP-PPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQR 132
L P + PP LP P V P PPPPP+PPPP
Sbjct: 459 GALPPAYGPPAHLPYHPHVYPPN------PPPPPVPPPPASF------------------ 494
Query: 133 DGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQP-------YLP 185
PP PP PG Y PP +Y P PPP PPT + P LP
Sbjct: 495 ------------PPPAIPPPTPG-YPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLP 541
Query: 186 PAQPSPSQSPPSQSYLAPTP 205
PA P PP P P
Sbjct: 542 PASYPPPAVPPGGQPPVPPP 561
Score = 68.9 bits (167), Expect = 5e-11
Identities = 83/334 (24%), Positives = 106/334 (31%), Gaps = 57/334 (17%)
Query: 60 QLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQK 119
Q+ L ++QM PHH P PP + P Q P P Q
Sbjct: 253 QILDLYSQGKQQM-----PHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS-----QP 302
Query: 120 QQQYKHQMLHHQRDGPPGLVPMELESPPESP-PVPPGSYMPPSQSYMPPPQPPPSYYPPT 178
QQ+ Q Q+ P P + P SP V + P + PPP
Sbjct: 303 QQKDPQQPAQQQQ---PAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIE 359
Query: 179 SSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQ-ASPSRPSQ 237
++ P LPPA P P + PP + L ++ LP Q P+ P+
Sbjct: 360 TTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATD----------LPKVQIPPPAHPAP 409
Query: 238 GHSKSQLLAPPPPSAPPGNKTTVQ-QEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQY 296
H L PPP P T + SG +S + P + P
Sbjct: 410 VHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP------ 463
Query: 297 WYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPP-LPP 355
HLP H P V P P VP P+S PP +PP
Sbjct: 464 ---------AYGPPAHLPYH---PHVYPPNPPP----------PPVPPPPASFPPPAIPP 501
Query: 356 PNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAH 389
P PPP P P P RL A H
Sbjct: 502 PTPGYPPPPPTYNPNF--PPPPPRLPPTHAVPPH 533
Score = 63.2 bits (152), Expect = 3e-09
Identities = 85/345 (24%), Positives = 122/345 (35%), Gaps = 52/345 (15%)
Query: 429 IQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGH 488
+ M + +L +E+Q+ + +Y+ W WE+ + P D L++ Q
Sbjct: 208 VAVMYLAGRLCKFEIQEWTSKPMYRRW------WEQFVQDVP-VDVLEDICHQ------- 253
Query: 489 MKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMP 548
Y Q K Q M + + PP P Q+P + P PS P P
Sbjct: 254 --ILDLYSQGK----QQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDP 307
Query: 549 --PAL---PATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPP-----PSLSS 598
PA PA P P P P + +V + ++ PPP +P P L
Sbjct: 308 QQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP 367
Query: 599 AGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQGI--PPQLTAAPVPP--- 653
A PPP PP L++ P P ++ P IPPP P + PP L P PP
Sbjct: 368 AHPPPDRKPP-LAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPS 426
Query: 654 --------ASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSAGPSEQVNSKAPLS 705
SS S + + + + S+G+ PP Y PP P
Sbjct: 427 SYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP-AYGPPAHLPYHPHVYPPNPPPP 485
Query: 706 KSALPYSSFSSDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPR 750
P +SF + P P T + P P PPR
Sbjct: 486 PVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFP-------PPPPR 523
Score = 62.4 bits (150), Expect = 5e-09
Identities = 32/67 (47%), Positives = 36/67 (53%), Gaps = 8/67 (11%)
Query: 1503 PGMYPPPGSYRP---PPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP---PPPPPPLP 1556
PG PPP +Y P PPP PP V P PP P + PP +PP PP PPP+P
Sbjct: 504 PGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIP 563
Query: 1557 PP--PPV 1561
PP PPV
Sbjct: 564 PPGMPPV 570
Score = 60.5 bits (145), Expect = 2e-08
Identities = 56/174 (32%), Positives = 65/174 (37%), Gaps = 40/174 (22%)
Query: 1482 EPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTR 1541
E + A+ PP+ +++ T PP PPP KPP + A P
Sbjct: 344 ENKAAEPPPPKIPKIETTH-------PPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDL 396
Query: 1542 PPVPIPP---------PPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLN 1592
P V IPP PPP P PPPPP T + Y Q L
Sbjct: 397 PKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGY--------QSLQ 448
Query: 1593 SEFKSETAAIPSAPVLPP---PPVHSSI--------PPPGPVPMGMPPMSKPPP 1635
S K+E PS LPP PP H PPP PVP PP S PPP
Sbjct: 449 SMMKTEG---PSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVP--PPPASFPPP 497
Score = 58.9 bits (141), Expect = 5e-08
Identities = 48/166 (28%), Positives = 56/166 (33%), Gaps = 59/166 (35%)
Query: 1503 PGMYPPPGSYRPPPPM------------------------------GKPPGSIVRPSAPP 1532
P PPP +RPPPP G G++ PP
Sbjct: 409 PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP 468
Query: 1533 ARSSV-PVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGL 1591
A P PP P PPP PPPP PPP I P T
Sbjct: 469 AHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYP--------------------- 507
Query: 1592 NSEFKSETAAIPSAPVLPP--PPVHSSIPPPGPVPMGMPPMSKPPP 1635
P+ P PP PP H ++PP P +G+PP S PPP
Sbjct: 508 ----PPPPTYNPNFPPPPPRLPPTH-AVPPHPPPGLGLPPASYPPP 548
Score = 57.0 bits (136), Expect = 2e-07
Identities = 41/112 (36%), Positives = 47/112 (41%), Gaps = 42/112 (37%)
Query: 15 PPPPVPPPP----PVALPEASPG-----PGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQ 65
PPPPVPPPP P A+P +PG P Y+ + P P +L
Sbjct: 483 PPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPP-----------------RLP 525
Query: 66 QMHQKQMQCVLQPHH-----LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPG 112
H + PH LPP PPP V PGG QPP PP PPPG
Sbjct: 526 PTH------AVPPHPPPGLGLPPASYPPPAVPPGG-----QPPVPPPIPPPG 566
Score = 56.6 bits (135), Expect = 3e-07
Identities = 47/141 (33%), Positives = 55/141 (39%), Gaps = 33/141 (23%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548
LPP + P +YPP PPPP+ PP S P+ PP P P
Sbjct: 461 LPPAYGPPAHLPYHPHVYPPNP---PPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNF 517
Query: 1549 PPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVL 1608
PPPPP LPP T AV + GL A+ P P +
Sbjct: 518 PPPPPRLPP--------THAV--------------PPHPPPGLG----LPPASYP-PPAV 550
Query: 1609 PP---PPVHSSIPPPGPVPMG 1626
PP PPV IPPPG P+G
Sbjct: 551 PPGGQPPVPPPIPPPGMPPVG 571
Score = 47.4 bits (111), Expect = 2e-04
Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 10/77 (12%)
Query: 1483 PQMADHLPPQESRLQNTSSRPGMYPPPGSY--RPPPPMGKPPGSIVRPSAPPARSSVPVT 1540
P + PP + N P PP + PPP +G PP S P+ PP
Sbjct: 501 PPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQP---- 556
Query: 1541 RPPVPIPPPPPPPPLPP 1557
P+PPP PPP +PP
Sbjct: 557 ----PVPPPIPPPGMPP 569
Score = 41.2 bits (95), Expect = 0.011
Identities = 42/160 (26%), Positives = 53/160 (33%), Gaps = 15/160 (9%)
Query: 1474 QKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPA 1533
Q SEP PQ+ Q +P P S +P P +V P
Sbjct: 290 QSQPSQSSEPSQPQQKDPQQPAQQQ---QPAQQPKKPSPQPSSPRQVKRAVVVSPKEENK 346
Query: 1534 RSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNS 1593
+ P + P PP PP PPP P +A+ E G D D +
Sbjct: 347 AAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAAL-----GEAEPPGPVDATDLPKVQI 401
Query: 1594 EFKSETAAIPSAPVLP--PPPVHSSIPPPGPVPMGMPPMS 1631
+ A + P LP PPP PPP GM S
Sbjct: 402 PPPAHPAPVHQPPPLPHRPPP-----PPPSSYMTGMSTTS 436
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 91.3 bits (225), Expect = 9e-18
Identities = 135/469 (28%), Positives = 180/469 (38%), Gaps = 67/469 (14%)
Query: 997 DKGLPRPDNR--DNRLEGN-----RGNSSSYRGP-------GQSRMEDTRDKGLVNRGR- 1041
D L R D+R D EG +S RGP G+ R ED + R R
Sbjct: 880 DSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPRR 939
Query: 1042 -GQAISRGPGLVKQED------FRDKMMGRREDSREKMNRGEGSRDRGLVRPGSSREKVP 1094
G R P L +D D RR ++ +R DR R ++ + P
Sbjct: 940 LGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWR--NTDDDRP 997
Query: 1095 GGLQGSQDRGA-AGSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPPRGPGSR 1153
+DRG + + PPRR ++RG R A E PRR +RGP RG
Sbjct: 998 PRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTAD--EDRGPRRGMDDDRGPRRGGADD 1055
Query: 1154 ERGLGRS---------DFGRDRGPFRPEPGDGGEKMYPYHRDEPPRAPWN--HGEERGHE 1202
ER R+ DRGP R D G + D PR + G RG +
Sbjct: 1056 ERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRR-GMDDDRGPRRGMDDDRGPRRGLD 1114
Query: 1203 EFPLDGRNAPMER-ERLDDWDRERYWRECERDYQDDTLELYNREDRFSAPPSRSHDGDRR 1261
+ RNA +R R D WR + DD L +DRF R D R
Sbjct: 1115 DDRGPWRNADDDRIPRRGAEDDRGPWRNMD----DDRLSRRADDDRFP----RRGDDSRP 1166
Query: 1262 GPW--------WDDWERDQDMDEDYNREM----ERDMDRDVDRISRPMDMYDRSLDNEWD 1309
GPW W + E+ ++ RE ER+ DR+ +R D + D E +
Sbjct: 1167 GPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERE 1226
Query: 1310 RDYGRPLDEQESQFRERDIPSLPPLPPLPPLPPLDRYR-DDRWREERNREHGYDRDFRDR 1368
RD R +D ++ R RD P D R DDR R++R RE RD R+R
Sbjct: 1227 RDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRER 1286
Query: 1369 GELRIREYPERGDTWREKRDYVPDRMDWER--ERLSDRWYPSDVDRHSP 1415
+LR + RG R +R+ V W R +R DR D R P
Sbjct: 1287 RDLR-DDRDRRGPPLRSEREEV---SSWRRADDRKDDRVEERDPPRRVP 1331
Score = 88.2 bits (217), Expect = 8e-17
Identities = 132/431 (30%), Positives = 166/431 (38%), Gaps = 69/431 (16%)
Query: 990 PHSENNQDKGLPRPDNRDNRLEGNRGNSSSYRGPGQSRMEDTRDKGLVNRGRGQAISRGP 1049
P N D PR ++R GN ++ R P + ED + RG RG
Sbjct: 987 PSWRNTDDDRPPRRIADEDR--GNWRHADDDRPPRRGLDEDRGSWRTADEDRGPR--RG- 1041
Query: 1050 GLVKQEDFRDKMMGRREDSREKMNRGEGSR--------DRGLVRPGSSREKVPGGLQG-S 1100
+D R G +D R + R DRG P + G +G
Sbjct: 1042 ----MDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRG---PRRGMDDDRGPRRGMD 1094
Query: 1101 QDRGAA-GSRERGPPRRAGSQERGPLRRAGSRERIPPRRAGSRERGPPRGP--------G 1151
DRG G + PRR +RGP R A +RIP RR +RGP R
Sbjct: 1095 DDRGPRRGMDDDRGPRRGLDDDRGPWRNADD-DRIP-RRGAEDDRGPWRNMDDDRLSRRA 1152
Query: 1152 SRERGLGRSDFGRDRGPFRPEPGDGGEKMYPYHRDE---PPRAPWNHGEERGHEEFPLDG 1208
+R R D R GP+RP GG + R+E PPR E R EE D
Sbjct: 1153 DDDRFPRRGDDSRP-GPWRPLVKPGGWREKEKAREESWGPPR------ESRPSEEREWDR 1205
Query: 1209 RNAPMERERLDDWDRERYWR--ECERDYQDDTLELYNREDRFSAPPSRSHDGDRRGPW-- 1264
ER+R D+ DRE + E ERD + D +REDRF P R G RRGP
Sbjct: 1206 EK---ERDR-DNQDREENDKDPERERDRERDV----DREDRFRRP--RDEGGWRRGPAEE 1255
Query: 1265 ---WDDWERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRS-----LDNEWDRDYGRPL 1316
W D R D D D +R ERD RD+ D DR + E + R
Sbjct: 1256 SSSWRDSSRRDDRDRD-DRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRAD 1314
Query: 1317 DEQESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREY 1376
D ++ + ERD P P PP DR RD E +E R +DR LR +
Sbjct: 1315 DRKDDRVEERDPPRRVP----PPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKN 1370
Query: 1377 PERGDTWREKR 1387
D W R
Sbjct: 1371 ETDEDGWTTVR 1381
Score = 43.1 bits (100), Expect = 0.003
Identities = 35/94 (37%), Positives = 46/94 (48%), Gaps = 16/94 (17%)
Query: 1683 RDRYDRERDREPYFDRQSNVIADHRDFKR-DRETHRDRDRDRGVIDYDRDRFDRERRPRD 1741
R +RE DRE DR D++D + D++ R+RDR+R D DR DR RRPRD
Sbjct: 1196 RPSEEREWDREKERDR------DNQDREENDKDPERERDRER-----DVDREDRFRRPRD 1244
Query: 1742 D----RAQSYRDKKDHSSSRRGGFDRPSYDRKSD 1771
+ R + SSRR DR R+ D
Sbjct: 1245 EGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERD 1278
Score = 40.4 bits (93), Expect = 0.019
Identities = 74/288 (25%), Positives = 99/288 (34%), Gaps = 65/288 (22%)
Query: 1178 EKMYPYHRDEPPRAPWNHGEERGHEEFPLDGRNAPMERERLDDWDRERYWRE-------- 1229
E+ Y+R++ E+R EE L R ERER + RE RE
Sbjct: 801 ERRITYYREKEEE------EQRRAEEQMLKERE---ERERAERAKREEELREYQERVKKL 851
Query: 1230 --CERDYQDDTLELYNREDR-----------FSAPPSRSHDGDRRGPWWDDWERDQDMDE 1276
ER + LE+ RE R S SR D D G W E D +
Sbjct: 852 EEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRR 911
Query: 1277 DY-NREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYGRPLDEQESQFRERDIPSLPPLP 1335
+E R RD DR R + R L ++ DR+ PSL P
Sbjct: 912 GPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDRE-----------------PSLRPDD 954
Query: 1336 PLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPERGDTWREKRDYVPDRMD 1395
P +D R R E +R F RG + +WR D P R
Sbjct: 955 DRVPRRGMDDDRGPRRGPEEDR-------FSRRGA------DDDRPSWRNTDDDRPPRRI 1001
Query: 1396 WERERLSDRWYPSDVDR--HSPMAEHMPSSHHSSEMMGSDASLDSDQG 1441
+ +R W +D DR + E S + E G +D D+G
Sbjct: 1002 ADEDR--GNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDRG 1047
Score = 34.3 bits (77), Expect = 1.4
Identities = 41/164 (25%), Positives = 55/164 (33%), Gaps = 30/164 (18%)
Query: 1628 PPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYD 1687
PP P ++ D RD E+ D PER + DR+
Sbjct: 1191 PPRESRPSEEREWDREKERDRDNQDREE----------NDKDPERERDRERDVDREDRFR 1240
Query: 1688 RERDR-----------EPYFDRQSNVIADHRDFKRDRETHRDRDRDRGVIDYDRDRFDRE 1736
R RD + D D D +R+R+ RD R+R + DRDR
Sbjct: 1241 RPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDL-RERRDLRDDRDRRGPP 1299
Query: 1737 RRPRDDRAQSYRDKKDHSSSRRGGFDRP--------SYDRKSDR 1772
R + S+R D R D P S DR+ DR
Sbjct: 1300 LRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDR 1343
Score = 34.3 bits (77), Expect = 1.4
Identities = 39/121 (32%), Positives = 55/121 (45%), Gaps = 29/121 (23%)
Query: 1665 RPDPLPERSTF-ETEHAGQRDRYDRERDREPYFD-RQSNVIADHRDFKR----------- 1711
R P E S++ ++ RDR DR R+R+ D R+ + D RD +
Sbjct: 1249 RRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVS 1308
Query: 1712 ------DRETHRDRDRD--RGVI------DYDRDRFDRERRPRDDRAQSYRDKKDHSSSR 1757
DR+ R +RD R V D +RDR DRER ++A S+R +KD S R
Sbjct: 1309 SWRRADDRKDDRVEERDPPRRVPPPALSRDRERDR-DREREGEKEKA-SWRAEKDRESLR 1366
Query: 1758 R 1758
R
Sbjct: 1367 R 1367
Score = 33.5 bits (75), Expect = 2.3
Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 29/139 (20%)
Query: 1712 DRETHRDRDRDRGV-IDYDRD---RFDRERRPR----DDRAQSYRDKKDHSSSRRGGFDR 1763
DR RD +R R + D DR+ R D +R PR DDR ++D S R DR
Sbjct: 927 DRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDR 986
Query: 1764 PSY-----DR----------------KSDRPVYEGPSMFGGERRTYPEERMPLPAPSLSH 1802
PS+ DR DRP G G RT E+R P
Sbjct: 987 PSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWRTADEDRGPRRGMDDDR 1046
Query: 1803 QPPPAPRVEKKPESKNVDD 1821
P +++ +N DD
Sbjct: 1047 GPRRGGADDERSSWRNADD 1065
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 90.5 bits (223), Expect = 2e-17
Identities = 74/208 (35%), Positives = 88/208 (42%), Gaps = 41/208 (19%)
Query: 512 GNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVM---PPALP---ATVPPPGM----- 560
G + PPP S PPP P PPP PP LP V PP+LP A PPP +
Sbjct: 584 GTIIPPPPAPGDSTTPPPPPPPPPP--PPPLPGGVCISSPPSLPGGTAISPPPPLSGDAT 641
Query: 561 --PPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPV 618
PPP +P + +P P P ++ PPP LP SA PP PP S+ PPP
Sbjct: 642 IPPPPPLPEGV--GIPSPSSLPGGTAIPPPPPLP----GSARIPPPPPPLPGSAGIPPPP 695
Query: 619 MPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTP---- 674
PLP + PPP P PG P GIPP PP P P + P P
Sbjct: 696 PPLPG-EAGMPPPPPPLPGGP-GIPP-------PPPFPGGPGIPPPPPGMGMPPPPPFGF 746
Query: 675 -------VSFGSAPPTTYHPPLQSAGPS 695
+ FG P Y P +Q P+
Sbjct: 747 GVPAAPVLPFGLTPKKLYKPEVQLRRPN 774
Score = 73.2 bits (178), Expect = 3e-12
Identities = 76/271 (28%), Positives = 104/271 (38%), Gaps = 55/271 (20%)
Query: 472 KDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMK---NQYMGNMSMPPPFVPYSQMPP 528
K ++E++ + QG A S Q+ Q+++ +Q G ++ + ++
Sbjct: 494 KKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEM 553
Query: 529 PLPTMPPPVLPPSLPPPV-MPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGP 587
+ +PPS+P +PPA P + PP P T+ PPP PP P
Sbjct: 554 ASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP-----P 608
Query: 588 PPVLP-------PPSL---SSAGPPPVL-------PPPSL-------------SSTAPPP 617
PP LP PPSL ++ PPP L PPP L TA PP
Sbjct: 609 PPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPP 668
Query: 618 VMPLPPLSSATPPP-------GIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKP---R 667
PLP + PPP GIPPP P +P + P PP P P
Sbjct: 669 PPPLPGSARIPPPPPPLPGSAGIPPP--PPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGG 726
Query: 668 PALLPTPVSFGSAPPTTYHPPLQSAGPSEQV 698
P + P P G PP PP P+ V
Sbjct: 727 PGIPPPPPGMGMPPP----PPFGFGVPAAPV 753
Score = 72.4 bits (176), Expect = 4e-12
Identities = 63/210 (30%), Positives = 74/210 (35%), Gaps = 84/210 (40%)
Query: 9 GGSSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68
G S+ PPPP PPPPP LP G S+ P+ P +
Sbjct: 594 GDSTTPPPPPPPPPPPPPLP-----GGVCISSPPSLPGGTAIS----------------- 631
Query: 69 QKQMQCVLQPHHLPPPPL------PPPPVMPGG---------GYGDWQPPPPPMP----- 108
PPPPL PPPP +P G G PPPPP+P
Sbjct: 632 -------------PPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 678
Query: 109 PPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMP-- 166
PPP P L G G+ PP PP+P + MPP +P
Sbjct: 679 PPPPPPL-----------------PGSAGI-------PPPPPPLPGEAGMPPPPPPLPGG 714
Query: 167 PPQPPPSYYPPTSSQPYLPPAQPSPSQSPP 196
P PPP PP P +PP P PP
Sbjct: 715 PGIPPP---PPFPGGPGIPPPPPGMGMPPP 741
Score = 63.5 bits (153), Expect = 2e-09
Identities = 96/373 (25%), Positives = 127/373 (34%), Gaps = 93/373 (24%)
Query: 565 MPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPL 624
+PPS+P+ P P PP +G ++PPP P P S+T PPP
Sbjct: 563 VPPSVPSRAPVPPAPPLPGDSGT--IIPPP-----------PAPGDSTTPPPP------- 602
Query: 625 SSATPPPGIPPPGVPQGI----PPQL---TAAPVPPASSSQSSQVPEKPRPALLPTPVSF 677
PPP PPP +P G+ PP L TA PP S ++ P P P + P S
Sbjct: 603 ----PPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIP-SP 657
Query: 678 GSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPSQPITAVKDM 737
S P T PP P +++ P LP G + P P +
Sbjct: 658 SSLPGGTAIPP----PPPLPGSARIPPPPPPLP----------GSAGIPPPPP-----PL 698
Query: 738 PVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRPRY 797
P +G P PP P GP P P P GP G P P
Sbjct: 699 PGEAGMPPPPPP------LPGGPGIPPP-----------PPFPGGP---GIPPPPPGMGM 738
Query: 798 EGHPAEGTKSKWGMIPRGPASQFYITPSTSLSP--RQSGPQWKGPKPAFGQQHQQQPKSQ 855
P G +P P F +TP P + P W K
Sbjct: 739 PPPPPFGFG-----VPAAPVLPFGLTPKKLYKPEVQLRRPNWS--------------KLV 779
Query: 856 AEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVS 915
AE LS + + N + +A K KA + E + ++ K +V
Sbjct: 780 AEDLSQDCFWTKVKEDRFENNELFAKLTLTFSAQTKTSKAKKDQEG-GEEKKSVQKKKVK 838
Query: 916 EGPVEPSNWDQNV 928
E V S QN+
Sbjct: 839 ELKVLDSKTAQNL 851
Score = 62.4 bits (150), Expect = 5e-09
Identities = 47/143 (32%), Positives = 60/143 (41%), Gaps = 46/143 (32%)
Query: 1507 PPP----GSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVP----IPPPPPPPP---- 1554
PPP + PPPP+ + G I PS+ P +++P PP+P IPPPPPP P
Sbjct: 633 PPPLSGDATIPPPPPLPEGVG-IPSPSSLPGGTAIPPP-PPLPGSARIPPPPPPLPGSAG 690
Query: 1555 LPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVH 1614
+PPPPP + + +P P +PPPP
Sbjct: 691 IPPPPPPLPGEAG---------------------------MPPPPPPLPGGPGIPPPPPF 723
Query: 1615 SSIP--PPGPVPMGMPPMSKPPP 1635
P PP P MGMPP PPP
Sbjct: 724 PGGPGIPPPPPGMGMPP---PPP 743
Score = 60.1 bits (144), Expect = 2e-08
Identities = 43/146 (29%), Positives = 53/146 (36%), Gaps = 59/146 (40%)
Query: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVP----I 1546
P S L ++ P P PGS R PPP PGS + +P PP+P +
Sbjct: 655 PSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGS----------AGIPPPPPPLPGEAGM 704
Query: 1547 PPPPPP----PPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAI 1602
PPPPPP P +PPPPP
Sbjct: 705 PPPPPPLPGGPGIPPPPP-----------------------------------------F 723
Query: 1603 PSAPVLPPPPVHSSIPPPGPVPMGMP 1628
P P +PPPP +PPP P G+P
Sbjct: 724 PGGPGIPPPPPGMGMPPPPPFGFGVP 749
Score = 59.7 bits (143), Expect = 3e-08
Identities = 63/219 (28%), Positives = 72/219 (32%), Gaps = 65/219 (29%)
Query: 82 PPPPLP-------PPPVMPGGGYGDWQPPPPPMPPPP---GPALSYQKQQQYKHQMLHHQ 131
P PPLP PPP PG PPPPP PPPP G +S
Sbjct: 575 PAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCIS--------------- 619
Query: 132 RDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQP---YLPPAQ 188
PP L SPP PP+ + +PP PPP P P SS P +PP
Sbjct: 620 --SPPSLPGGTAISPP--PPLSGDATIPP-----PPPLPEGVGIPSPSSLPGGTAIPPPP 670
Query: 189 PSPSQS--PPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLA 246
P P + PP P P LP S P P ++ +
Sbjct: 671 PLPGSARIPPP-----PPP-------------------LPGSAGIPPPPPPLPGEAGM-- 704
Query: 247 PPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDP 285
PPPP PG P G P P P
Sbjct: 705 PPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPPPP 743
Score = 59.3 bits (142), Expect = 4e-08
Identities = 65/257 (25%), Positives = 91/257 (35%), Gaps = 71/257 (27%)
Query: 1422 SSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGS 1481
++ H ++ D +Q L + H + A E + L + QL G
Sbjct: 484 TARHELQVEMKKMESDFEQKLQDLQGEKDALHSEKQQIATEKQDLEAEVSQLT-----GE 538
Query: 1482 EPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPP----PPMGKPPGSIVRPSAPPARSSV 1537
++ L + + + S+ PP R P PP+ G+I+ P P S+
Sbjct: 539 VAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTT 598
Query: 1538 PVTRPPVPIPPPP--------------------PPPPL------PPPPPVIKPQTSAVEQ 1571
P PP P PPPP PPPPL PPPPP+ P+ +
Sbjct: 599 PPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL--PEGVGIPS 656
Query: 1572 ERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPV-------LPPPPVHSSI---PPPG 1621
S TA P P+ PPPP+ S PPP
Sbjct: 657 P--------------------SSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP 696
Query: 1622 PVP--MGMPPMSKPPPV 1636
P+P GMPP PPP+
Sbjct: 697 PLPGEAGMPP--PPPPL 711
Score = 51.6 bits (122), Expect = 8e-06
Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVP--- 1545
+PP + P P PGS PPP PG P PP P PP P
Sbjct: 666 IPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPG 725
Query: 1546 ---IPPPPPPPPLPPPPP 1560
IPPPPP +PPPPP
Sbjct: 726 GPGIPPPPPGMGMPPPPP 743
Score = 48.9 bits (115), Expect = 5e-05
Identities = 53/224 (23%), Positives = 66/224 (29%), Gaps = 49/224 (21%)
Query: 145 SPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPT 204
S P PVPP +P + PP P P S+ P PP P P P ++
Sbjct: 566 SVPSRAPVPPAPPLPGDSGTIIPPPPAPG----DSTTPPPPPPPPPPPPPLPGGVCISSP 621
Query: 205 PSYSSSSSSSQSYLSHSQSYLPSSQASPSR---PSQGHSKSQLLAPPPPSAPPGNKTTVQ 261
PS ++ S + +P P PS PPPP P +
Sbjct: 622 PSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP 681
Query: 262 QEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPV 321
PL A P P P LPG P
Sbjct: 682 PPPLPGSA---------GIPPPPPP--------------------------LPGEAGMP- 705
Query: 322 VAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLP 365
P P+ +P P P P PPP +PPP P
Sbjct: 706 ---PPPPPLPGGPGIPPPPPFPGGPGI---PPPPPGMGMPPPPP 743
Score = 48.1 bits (113), Expect = 9e-05
Identities = 42/140 (30%), Positives = 52/140 (37%), Gaps = 27/140 (19%)
Query: 83 PPPLPPPPVMPGGG-----------YGD-WQPPPPPMPPPPGPALSYQKQQQYKHQMLHH 130
P P PP P G GD PPPPP PPPP P L +
Sbjct: 568 PSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGG 627
Query: 131 QRDGPPGLVPMELESPPESPPVPPGSYMP-----PSQSYMPPP---------QPPPSYYP 176
PP + + PP PP+P G +P P + +PPP PPP P
Sbjct: 628 TAISPPPPLSGDATIPP-PPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP 686
Query: 177 PTSSQPYLPPAQPSPSQSPP 196
++ P PP P + PP
Sbjct: 687 GSAGIPPPPPPLPGEAGMPP 706
Score = 42.0 bits (97), Expect = 0.006
Identities = 38/136 (27%), Positives = 50/136 (36%), Gaps = 17/136 (12%)
Query: 232 PSRPSQGHSKSQLLAPPPPSAP-PGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTP 290
PS PS+ AP PP+ P PG+ T+ P G P P P P
Sbjct: 565 PSVPSR--------APVPPAPPLPGDSGTIIPPPPAPG-------DSTTPPPPPPPPPPP 609
Query: 291 QEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEE 350
SL T + P G P P+ E V +P+ S +P +
Sbjct: 610 PPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPP-PLPEGVGIPSPSSLPGGTAIPP 668
Query: 351 PPLPPPNEEVPPPLPP 366
PP P + +PPP PP
Sbjct: 669 PPPLPGSARIPPPPPP 684
Score = 32.7 bits (73), Expect = 3.9
Identities = 15/48 (31%), Positives = 18/48 (37%)
Query: 327 PEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374
P V VP +P + PP P P + PP PP P P
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPP 611
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 129,385,691
Number of Sequences: 37866
Number of extensions: 10060842
Number of successful extensions: 267119
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1344
Number of HSP's successfully gapped in prelim test: 2800
Number of HSP's that attempted gapping in prelim test: 52030
Number of HSP's gapped (non-prelim): 97644
length of query: 2146
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2028
effective length of database: 13,779,330
effective search space: 27944481240
effective search space used: 27944481240
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.