Guide to the Human Genome
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Search of human proteins with 14589849

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14589849 guanine nucleotide binding protein-gamma
transducing activity polypeptide 2 [Homo sapiens]
         (69 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14589849 guanine nucleotide binding protein-gamma transducing...   140   3e-34
gi|4758448 guanine nucleotide binding protein gamma 11 precursor...    95   1e-20
gi|11386179 guanine nucleotide binding protein (G protein), gamm...    92   9e-20
gi|32698769 guanine nucleotide binding protein (G protein), gamm...    56   5e-09
gi|51036603 G-protein gamma-12 subunit [Homo sapiens]                  54   3e-08
gi|54114974 guanine nucleotide binding protein (G protein), gamm...    51   2e-07
gi|6912394 guanine nucleotide binding protein (G protein), gamma...    48   2e-06
gi|63055067 guanine nucleotide binding protein (G protein), gamm...    46   6e-06
gi|15147246 guanine nucleotide binding protein (G protein), gamm...    45   1e-05
gi|148922937 guanine nucleotide binding protein (G protein), gam...    45   2e-05
gi|148922892 guanine nucleotide binding protein (G protein), gam...    45   2e-05
gi|4758450 guanine nucleotide binding protein (G protein), gamma...    45   2e-05
gi|4885287 guanine nucleotide binding protein (G protein), gamma...    42   1e-04
gi|7706567 guanine nucleotide binding protein (G protein), gamma...    38   0.002
gi|169213736 PREDICTED: similar to hCG1650801 [Homo sapiens]           38   0.002
gi|169214197 PREDICTED: similar to hCG1650801 [Homo sapiens]           38   0.002
gi|169213540 PREDICTED: similar to hCG1650801 [Homo sapiens]           38   0.002
gi|21361097 DNAJC25-GNG10 protein [Homo sapiens]                       35   0.010
gi|146219841 PNMA-like 2 [Homo sapiens]                                32   0.11 
gi|153945846 inositol 1,4,5-triphosphate receptor, type 3 [Homo ...    32   0.14 
gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]    29   0.70 
gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]     29   0.70 
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H...    29   0.70 
gi|71061468 centromere protein E [Homo sapiens]                        28   1.6  
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform...    28   2.0  
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform...    28   2.0  
gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]         27   2.7  
gi|16076875 tripartite motif-containing 7 isoform 4 [Homo sapiens]     27   2.7  
gi|109134347 NY-REN-58 antigen [Homo sapiens]                          27   3.5  
gi|109134355 NY-REN-58 antigen [Homo sapiens]                          27   3.5  

>gi|14589849 guanine nucleotide binding protein-gamma transducing
          activity polypeptide 2 [Homo sapiens]
          Length = 69

 Score =  140 bits (352), Expect = 3e-34
 Identities = 69/69 (100%), Positives = 69/69 (100%)

Query: 1  MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPF 60
          MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPF
Sbjct: 1  MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPF 60

Query: 61 KEKGGCLIS 69
          KEKGGCLIS
Sbjct: 61 KEKGGCLIS 69


>gi|4758448 guanine nucleotide binding protein gamma 11 precursor
          [Homo sapiens]
          Length = 73

 Score = 95.1 bits (235), Expect = 1e-20
 Identities = 44/67 (65%), Positives = 54/67 (80%)

Query: 3  QDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKE 62
          +DL EK+ LKMEVEQL+KEVK  R  +SK  +EIK Y+E ++G DP +KGIPEDKNPFKE
Sbjct: 7  EDLPEKEKLKMEVEQLRKEVKLQRQQVSKCSEEIKNYIEERSGEDPLVKGIPEDKNPFKE 66

Query: 63 KGGCLIS 69
          KG C+IS
Sbjct: 67 KGSCVIS 73


>gi|11386179 guanine nucleotide binding protein (G protein), gamma
          transducing activity polypeptide 1 [Homo sapiens]
          Length = 74

 Score = 92.0 bits (227), Expect = 9e-20
 Identities = 44/68 (64%), Positives = 57/68 (83%), Gaps = 1/68 (1%)

Query: 3  QDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKE 62
          +DL+EKD LKMEV+QLKKEV   R+ +SK  +E+++YVE ++G DP +KGIPEDKNPFKE
Sbjct: 7  EDLTEKDKLKMEVDQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPEDKNPFKE 66

Query: 63 -KGGCLIS 69
           KGGC+IS
Sbjct: 67 LKGGCVIS 74


>gi|32698769 guanine nucleotide binding protein (G protein), gamma
          7 [Homo sapiens]
          Length = 68

 Score = 56.2 bits (134), Expect = 5e-09
 Identities = 26/54 (48%), Positives = 34/54 (62%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEKGGCLI 68
          VEQL+ E    RI +SKA  ++  Y E  A NDP L G+P  +NPFK+K  C+I
Sbjct: 14 VEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVPASENPFKDKKPCII 67


>gi|51036603 G-protein gamma-12 subunit [Homo sapiens]
          Length = 72

 Score = 53.9 bits (128), Expect = 3e-08
 Identities = 25/54 (46%), Positives = 34/54 (62%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEKGGCLI 68
          V+QL+ E    RI +SKA  ++  Y E  A +DP L GIP  +NPFK+K  C+I
Sbjct: 18 VQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCII 71


>gi|54114974 guanine nucleotide binding protein (G protein), gamma
          2 [Homo sapiens]
          Length = 71

 Score = 50.8 bits (120), Expect = 2e-07
 Identities = 24/49 (48%), Positives = 30/49 (61%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
          VEQLK E    RI +SKA  ++  Y EA A  DP L  +P  +NPF+EK
Sbjct: 16 VEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREK 64


>gi|6912394 guanine nucleotide binding protein (G protein), gamma
          3 [Homo sapiens]
          Length = 75

 Score = 47.8 bits (112), Expect = 2e-06
 Identities = 22/49 (44%), Positives = 30/49 (61%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
          VEQLK E    RI +SKA  ++  Y +A A  DP +  +P  +NPF+EK
Sbjct: 20 VEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPTSENPFREK 68


>gi|63055067 guanine nucleotide binding protein (G protein), gamma
          10 [Homo sapiens]
          Length = 68

 Score = 46.2 bits (108), Expect = 6e-06
 Identities = 23/58 (39%), Positives = 32/58 (55%)

Query: 11 LKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEKGGCLI 68
          L+  VEQLK E    RI +S+A  E+++Y    A  D  L G+P   NPF+E   C +
Sbjct: 10 LQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRSCAL 67


>gi|15147246 guanine nucleotide binding protein (G protein), gamma
          8 [Homo sapiens]
          Length = 70

 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 21/63 (33%), Positives = 38/63 (60%)

Query: 1  MAQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPF 60
          M+ ++++    +  VEQLK EV   R+ +S+A  E+  + E  A +DP +  +P  +NPF
Sbjct: 1  MSNNMAKIAEARKTVEQLKLEVNIDRMKVSQAAAELLAFCETHAKDDPLVTPVPAAENPF 60

Query: 61 KEK 63
          ++K
Sbjct: 61 RDK 63


>gi|148922937 guanine nucleotide binding protein (G protein),
          gamma 4 [Homo sapiens]
          Length = 75

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 20/49 (40%), Positives = 29/49 (59%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
          VEQLK E    R+ +S+A  ++  Y EA    DP +  +P  +NPF+EK
Sbjct: 20 VEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68


>gi|148922892 guanine nucleotide binding protein (G protein),
          gamma 4 [Homo sapiens]
          Length = 75

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 20/49 (40%), Positives = 29/49 (59%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
          VEQLK E    R+ +S+A  ++  Y EA    DP +  +P  +NPF+EK
Sbjct: 20 VEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68


>gi|4758450 guanine nucleotide binding protein (G protein), gamma
          4 [Homo sapiens]
          Length = 75

 Score = 44.7 bits (104), Expect = 2e-05
 Identities = 20/49 (40%), Positives = 29/49 (59%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
          VEQLK E    R+ +S+A  ++  Y EA    DP +  +P  +NPF+EK
Sbjct: 20 VEQLKMEACMDRVKVSQAAADLLAYCEAHVREDPLIIPVPASENPFREK 68


>gi|4885287 guanine nucleotide binding protein (G protein), gamma
          5 [Homo sapiens]
          Length = 68

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 18/56 (32%), Positives = 32/56 (57%)

Query: 11 LKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEKGGC 66
          +K  V+QL+ E    R+ +S+A  ++K++    A +DP L G+    NPF+ +  C
Sbjct: 10 MKKVVQQLRLEAGLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSSSTNPFRPQKVC 65


>gi|7706567 guanine nucleotide binding protein (G protein), gamma
          13 [Homo sapiens]
          Length = 67

 Score = 38.1 bits (87), Expect = 0.002
 Identities = 22/58 (37%), Positives = 30/58 (51%)

Query: 11 LKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEKGGCLI 68
          +K EVE LK ++   R   SK   E+ +++E     DPFL       NP+ EKG C I
Sbjct: 9  MKKEVESLKYQLAFQREMASKTIPELLKWIEDGIPKDPFLNPDLMKNNPWVEKGKCTI 66


>gi|169213736 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 21/49 (42%), Positives = 28/49 (57%), Gaps = 3/49 (6%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
          VEQL+ E    ++   K   ++ ++   QA NDPFL GIP   N FKEK
Sbjct: 18 VEQLQMEAGIDQV---KMAADLLKFCTEQAKNDPFLVGIPAATNSFKEK 63


>gi|169214197 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 21/49 (42%), Positives = 28/49 (57%), Gaps = 3/49 (6%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
          VEQL+ E    ++   K   ++ ++   QA NDPFL GIP   N FKEK
Sbjct: 18 VEQLQMEAGIDQV---KMAADLLKFCTEQAKNDPFLVGIPAATNSFKEK 63


>gi|169213540 PREDICTED: similar to hCG1650801 [Homo sapiens]
          Length = 69

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 21/49 (42%), Positives = 28/49 (57%), Gaps = 3/49 (6%)

Query: 15 VEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
          VEQL+ E    ++   K   ++ ++   QA NDPFL GIP   N FKEK
Sbjct: 18 VEQLQMEAGIDQV---KMAADLLKFCTEQAKNDPFLVGIPAATNSFKEK 63


>gi|21361097 DNAJC25-GNG10 protein [Homo sapiens]
          Length = 153

 Score = 35.4 bits (80), Expect = 0.010
 Identities = 14/42 (33%), Positives = 23/42 (54%)

Query: 27  IPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEKGGCLI 68
           + +S+A  E+++Y    A  D  L G+P   NPF+E   C +
Sbjct: 111 LKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRSCAL 152


>gi|146219841 PNMA-like 2 [Homo sapiens]
          Length = 635

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 13/50 (26%), Positives = 29/50 (58%)

Query: 2   AQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLK 51
           + +  ++D L+  +  + K+   TR+ + +AG+E+   V  +AG+D  L+
Sbjct: 363 SDEKDKRDPLRQVLSVMSKDTNGTRVKVEEAGREVDAVVLRKAGDDGDLR 412


>gi|153945846 inositol 1,4,5-triphosphate receptor, type 3 [Homo
            sapiens]
          Length = 2671

 Score = 31.6 bits (70), Expect = 0.14
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 2/64 (3%)

Query: 2    AQDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFK 61
            AQD+    ++K E+++L+  V+ + + + K G    E VEA A  D   K  P D+  F 
Sbjct: 1101 AQDVENYKVIKSELDRLRTMVEKSELWVDKKGSGKGEEVEAGAAKDK--KERPTDEEGFL 1158

Query: 62   EKGG 65
               G
Sbjct: 1159 HPPG 1162


>gi|48762942 huntingtin interacting protein-1-related [Homo sapiens]
          Length = 1068

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 17/58 (29%), Positives = 29/58 (50%)

Query: 6   SEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
           S KD   +++E LK+EV+  R  + K   E + Y+         L+G  E++   K+K
Sbjct: 347 SVKDDRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQK 404


>gi|239750456 PREDICTED: similar to KIAA0655 protein [Homo sapiens]
          Length = 1048

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 17/58 (29%), Positives = 29/58 (50%)

Query: 6   SEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKEK 63
           S KD   +++E LK+EV+  R  + K   E + Y+         L+G  E++   K+K
Sbjct: 327 SVKDDRDLQIESLKREVEMLRSELEKIKLEAQRYIAQLKSQVNALEGELEEQRKQKQK 384


>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
           sapiens]
          Length = 217

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 1/50 (2%)

Query: 4   DLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQ-AGNDPFLKG 52
           DL  KD    E E  K E+K T +   K  KE+ E +++  + ND   KG
Sbjct: 153 DLLAKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSNDKKTKG 202


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 16/60 (26%), Positives = 28/60 (46%)

Query: 3    QDLSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPFKE 62
            +++SE      E+E LK E+KN  + +     E  E  +    N   +K I +++   KE
Sbjct: 1148 EEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKE 1207



 Score = 26.9 bits (58), Expect = 3.5
 Identities = 11/31 (35%), Positives = 21/31 (67%)

Query: 1    MAQDLSEKDLLKMEVEQLKKEVKNTRIPISK 31
            + +D++E      E+EQLKK++K+  + +SK
Sbjct: 1835 LKKDVNETQKKVSEMEQLKKQIKDQSLTLSK 1865


>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
           [Homo sapiens]
          Length = 1814

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 11  LKMEVEQLKKEVKNTRIPISKAGKEIKEYVEA 42
           LK+EVE LK+E++     + KA K ++   EA
Sbjct: 106 LKVEVESLKRELQEREQLLIKASKAVESLAEA 137


>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
           [Homo sapiens]
          Length = 1893

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 11  LKMEVEQLKKEVKNTRIPISKAGKEIKEYVEA 42
           LK+EVE LK+E++     + KA K ++   EA
Sbjct: 106 LKVEVESLKRELQEREQLLIKASKAVESLAEA 137


>gi|156627563 regulator of G-protein signaling 7 [Homo sapiens]
          Length = 487

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/53 (26%), Positives = 27/53 (50%), Gaps = 1/53 (1%)

Query: 8   KDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDPFLKGIPEDKNPF 60
           +D L+ +++  + ++   R+ +SK    +  Y E     DPFL   P+  NP+
Sbjct: 255 EDELQQQIKYWQIQLDRHRLKMSKVADSLLSYTEQYLEYDPFLLP-PDPSNPW 306


>gi|16076875 tripartite motif-containing 7 isoform 4 [Homo sapiens]
          Length = 221

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/41 (36%), Positives = 24/41 (58%)

Query: 8   KDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVEAQAGNDP 48
           K+LL+  +  LKKE+++  +  S   KE KE + +QA   P
Sbjct: 174 KELLESRLRVLKKELEDCEVFRSTEKKESKELLVSQAPAGP 214


>gi|109134347 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 14/37 (37%), Positives = 22/37 (59%)

Query: 5   LSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVE 41
           L+   +LK  VE+LK+E +N R    KA  E ++ +E
Sbjct: 493 LNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLE 529


>gi|109134355 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 14/37 (37%), Positives = 22/37 (59%)

Query: 5   LSEKDLLKMEVEQLKKEVKNTRIPISKAGKEIKEYVE 41
           L+   +LK  VE+LK+E +N R    KA  E ++ +E
Sbjct: 493 LNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLE 529


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.132    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,606,612
Number of Sequences: 37866
Number of extensions: 93633
Number of successful extensions: 451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 409
Number of HSP's gapped (non-prelim): 51
length of query: 69
length of database: 18,247,518
effective HSP length: 42
effective length of query: 27
effective length of database: 16,657,146
effective search space: 449742942
effective search space used: 449742942
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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