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Search of human proteins with 145699105
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|145699105 connexin40.1 [Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145699105 connexin40.1 [Homo sapiens] 759 0.0
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 155 4e-38
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 154 1e-37
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 153 3e-37
gi|22779877 connexin 46 [Homo sapiens] 153 3e-37
gi|55953076 connexin 50 [Homo sapiens] 146 3e-35
gi|62865885 connexin 37 [Homo sapiens] 145 4e-35
gi|32483412 connexin 40 [Homo sapiens] 144 2e-34
gi|6631083 connexin 40 [Homo sapiens] 144 2e-34
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 142 4e-34
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 142 4e-34
gi|122939172 connexin 45 [Homo sapiens] 142 5e-34
gi|69122473 connexin 45 [Homo sapiens] 142 5e-34
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 140 1e-33
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 135 8e-32
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 135 8e-32
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 135 8e-32
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 135 8e-32
gi|42558283 gap junction protein beta 2 [Homo sapiens] 131 1e-30
gi|4504001 connexin 43 [Homo sapiens] 130 2e-30
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 126 3e-29
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 126 3e-29
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 122 4e-28
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 122 5e-28
gi|54607056 connexin 31 [Homo sapiens] 122 7e-28
gi|13128960 connexin 31 [Homo sapiens] 122 7e-28
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 92 6e-19
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 85 1e-16
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 85 1e-16
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 85 1e-16
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 759 bits (1959), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPG 60
MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPG
Sbjct: 1 MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPG 60
Query: 61 CANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASG 120
CANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASG
Sbjct: 61 CANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASG 120
Query: 121 QRRCPRPFGERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPC 180
QRRCPRPFGERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPC
Sbjct: 121 QRRCPRPFGERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPC 180
Query: 181 TGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQS 240
TGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQS
Sbjct: 181 TGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQS 240
Query: 241 GASGHAEGRRTDEEGGREEEGAPAPPGARAGGEGAGSPRRTSRVSGHTKIPDEDESEVTS 300
GASGHAEGRRTDEEGGREEEGAPAPPGARAGGEGAGSPRRTSRVSGHTKIPDEDESEVTS
Sbjct: 241 GASGHAEGRRTDEEGGREEEGAPAPPGARAGGEGAGSPRRTSRVSGHTKIPDEDESEVTS 300
Query: 301 SASEKLGRQPRGRPHREAAQDPRGSGSEEQPSAAPSRLAAPPSCSSLQPPDPPASSSGAP 360
SASEKLGRQPRGRPHREAAQDPRGSGSEEQPSAAPSRLAAPPSCSSLQPPDPPASSSGAP
Sbjct: 301 SASEKLGRQPRGRPHREAAQDPRGSGSEEQPSAAPSRLAAPPSCSSLQPPDPPASSSGAP 360
Query: 361 HLRARKSEWV 370
HLRARKSEWV
Sbjct: 361 HLRARKSEWV 370
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 155 bits (393), Expect = 4e-38
Identities = 89/256 (34%), Positives = 139/256 (54%), Gaps = 15/256 (5%)
Query: 5 DLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANV 64
+LLG ++ ++ + T+VGK+W + + RMLV+ +A V+ DEQ F CNT QPGC N+
Sbjct: 5 NLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNI 64
Query: 65 CYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHR-----------GATLAALGPRRCPD 113
CYD P+S +RFW++Q + V PS V+ + L+R + L A D
Sbjct: 65 CYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPDLD 124
Query: 114 PREPASGQRRCPRPFGERGGLQVP---DFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAP 170
E R R ++ +VP Y++H+L R++LE F Y L+GF
Sbjct: 125 LEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYGFQMH 184
Query: 171 KKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLV-CSLRRRMRRRPG 229
+ CT+PPC VDC+VSRPTEK++ MLF+ +++A+S LL + ++ +R+ MR
Sbjct: 185 PLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYK 244
Query: 230 PPTSPSIRKQSGASGH 245
+S I ++G H
Sbjct: 245 KSSSEGIEDETGPPFH 260
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 154 bits (389), Expect = 1e-37
Identities = 94/296 (31%), Positives = 136/296 (45%), Gaps = 72/296 (24%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ ++ + T VGK+W + ++ R+++ + G +Y DEQ +F CNT QPGC NVCYD F
Sbjct: 12 LLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDNVCYDAF 71
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAAL----------GPRRCP------- 112
+P+SH+RFW+ Q V + PS ++ Y +HR A + GPRR P
Sbjct: 72 APLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPRAHLPPP 131
Query: 113 -----------------------------------DPREPASGQRRC------------- 124
+ E A + C
Sbjct: 132 HAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTKAVGADGKAAGT 191
Query: 125 PRPFGERGG---LQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCT 181
P P G+ G +Q Y+ L+ R E AF Y L+GF FPC+R PC
Sbjct: 192 PGPTGQHDGRRRIQREGLMRVYVAQLVARAAFEVAFLVGQYLLYGFEVRPFFPCSRQPCP 251
Query: 182 GVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADL----VCSLRRRMRRRPGPPTS 233
VVDC+VSRPTEK++ +L ++ VS L LL L ++ + S + +R R GPP S
Sbjct: 252 HVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGLGSAQDAVRGRRGPPAS 307
Score = 30.4 bits (67), Expect = 2.7
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 7/73 (9%)
Query: 221 RRRMRRRPGPPTSPSIRKQSGASGHAEGRRTDEE-------GGREEEGAPAPPGARAGGE 273
RR +RRRPGP +P +G E EE EEE A GA E
Sbjct: 111 RRALRRRPGPRRAPRAHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAE 170
Query: 274 GAGSPRRTSRVSG 286
AG+ ++ G
Sbjct: 171 EAGAEEACTKAVG 183
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 153 bits (386), Expect = 3e-37
Identities = 88/221 (39%), Positives = 115/221 (52%), Gaps = 29/221 (13%)
Query: 7 LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66
LG L+ + +VG+LW V+ ++ R+LV+ G V++DEQE FVCNTLQPGC CY
Sbjct: 7 LGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPGCRQTCY 66
Query: 67 DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHR------GATLAA-----LGPRRCPDPR 115
D PVSH RFWL + + P +F VY +HR GA AA L +C
Sbjct: 67 DRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHRAGKEAGGAEAAAQCAPGLPEAQCAPCA 126
Query: 116 EPASGQRRCPRPFGERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPC 175
A RRC Y++ + LR L E F L+GF F C
Sbjct: 127 LRARRARRC------------------YLLSVALRLLAELTFLGGQALLYGFRVAPHFAC 168
Query: 176 TRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADL 216
PPC VDC+VSRPTEK++ +LF +AV LS LL +A+L
Sbjct: 169 AGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAEL 209
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 153 bits (386), Expect = 3e-37
Identities = 112/373 (30%), Positives = 167/373 (44%), Gaps = 44/373 (11%)
Query: 7 LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66
LG L+ + T++GK+W + + R+LV+ A V+ DEQ F CNT QPGC NVCY
Sbjct: 7 LGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPGCENVCY 66
Query: 67 DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLH--------RGATLAALGPRRCPDPREPA 118
D P+SH+RFW +Q + V P+ ++ +VLH + R P P+EP
Sbjct: 67 DRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESPSPKEPP 126
Query: 119 SGQRRCPRPFGERGGLQVPD-FSAGYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTR 177
P +RG +++ Y+ +++ +TL E F A YFL+GF + C R
Sbjct: 127 QDN---PSSRDDRGRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKPLYRCDR 183
Query: 178 PPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLV----CSLRRRMRRRPG---- 229
PC VDC++SRPTEK++ ++F+ AV+ S LL + ++ L++ + R G
Sbjct: 184 WPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSRLGPDAS 243
Query: 230 ---------PPTSPSIRKQSGASGHAE--GRRTDEEGGREEEGAP-APPGAR-----AGG 272
PP PS R + A G G G P APP A A
Sbjct: 244 EAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADFKLLALT 303
Query: 273 EGAGSPRRTSRVSGHTKIPDEDESEVTSSASEKLGRQP---RGRPHREAAQDPRGSGSEE 329
E G + +GH + +++ +A RQP + P P GS
Sbjct: 304 EARGKGQSAKLYNGHHHLLMTEQNWANQAAE----RQPPALKAYPAASTPAAPSPVGSSS 359
Query: 330 QPSAAPSRLAAPP 342
P A + A P
Sbjct: 360 PPLAHEAEAGAAP 372
Score = 28.9 bits (63), Expect = 7.7
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 12/79 (15%)
Query: 261 GAPAPP---GARAGG-----EGAGSPRRTSRVSGHTKIPDEDESEVTSSASEKLGRQPRG 312
G+ +PP A AG +G+GS S ++G P+E+E VT++A P G
Sbjct: 356 GSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAG---TPEEEEQAVTTAAQMHQPPLPLG 412
Query: 313 RPHREAAQDPRGSGSEEQP 331
P R A++ R S +P
Sbjct: 413 DPGR-ASKASRASSGRARP 430
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 146 bits (368), Expect = 3e-35
Identities = 80/223 (35%), Positives = 125/223 (56%), Gaps = 18/223 (8%)
Query: 7 LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66
LG ++ +N + T++G++W + + R+L++ A V+ DEQ FVCNT QPGC NVCY
Sbjct: 7 LGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCY 66
Query: 67 DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPR 126
D P+SH+R W++Q + V PS +YV H + R+ + E GQ+
Sbjct: 67 DEAFPISHIRLWVLQIIFVSTPSL---MYVGHAVHYVRMEEKRKSREAEE--LGQQAGTN 121
Query: 127 PFGERGGLQVPDFSAG-------------YIIHLLLRTLLEAAFGALHYFLFGFLAPKKF 173
++G ++ S G YI H++ +TL E F HYFL+GF +
Sbjct: 122 GGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPLY 181
Query: 174 PCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADL 216
C+R PC VVDC+VSRPTEK++ +LF+ +V+++S L + +L
Sbjct: 182 RCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMEL 224
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 145 bits (367), Expect = 4e-35
Identities = 87/233 (37%), Positives = 132/233 (56%), Gaps = 19/233 (8%)
Query: 19 TMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVSHLRFW 78
T+VGK+W + + R+L++ LAG V+ DEQ F CNT QPGC NVCYD P+SH+R+W
Sbjct: 19 TVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGCTNVCYDQAFPISHIRYW 78
Query: 79 LIQGVCVLLPSAVFSVYVLH----------RGATLAALGPRRCPDPREPASGQRRCPR-P 127
++Q + V P+ V+ +V++ + L AL + R A+ +R+ +
Sbjct: 79 VLQFLFVSTPTLVYLGHVIYLSRREERLRQKEGELRALPAKDPQVERALAAVERQMAKIS 138
Query: 128 FGERGGLQVPDFSAG-YIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCTGVVDC 186
E G L++ G Y+ +L +++LEA F + L+G+ F C R PC +VDC
Sbjct: 139 VAEDGRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLYGWTMEPVFVCQRAPCPYLVDC 198
Query: 187 YVSRPTEKSLLMLFLWAVSALSFLLGLADLV---C-SLRRRMRRRPG---PPT 232
+VSRPTEK++ ++F+ V +S +L L +LV C L R MR R G PPT
Sbjct: 199 FVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLSRGMRARQGQDAPPT 251
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 144 bits (362), Expect = 2e-34
Identities = 81/232 (34%), Positives = 123/232 (53%), Gaps = 12/232 (5%)
Query: 7 LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66
LG + ++ + T+VGK+W + + RMLV+ A + DEQ F C+T+QPGC NVCY
Sbjct: 7 LGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCY 66
Query: 67 DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPR 126
D P+SH+R+W++Q + V PS V+ + +H R +E G
Sbjct: 67 DQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKE-VRGSGSYEY 125
Query: 127 PFGERGGLQVPDFSAG-----------YIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPC 175
P E+ L + G Y+ +L+RT +E F YF++G C
Sbjct: 126 PVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVC 185
Query: 176 TRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227
R PC V+CYVSRPTEK++ ++F+ AV+ALS LL LA+L +++R+R
Sbjct: 186 RRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQR 237
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 144 bits (362), Expect = 2e-34
Identities = 81/232 (34%), Positives = 123/232 (53%), Gaps = 12/232 (5%)
Query: 7 LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66
LG + ++ + T+VGK+W + + RMLV+ A + DEQ F C+T+QPGC NVCY
Sbjct: 7 LGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPGCQNVCY 66
Query: 67 DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPR 126
D P+SH+R+W++Q + V PS V+ + +H R +E G
Sbjct: 67 DQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKE-VRGSGSYEY 125
Query: 127 PFGERGGLQVPDFSAG-----------YIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPC 175
P E+ L + G Y+ +L+RT +E F YF++G C
Sbjct: 126 PVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLTTLHVC 185
Query: 176 TRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227
R PC V+CYVSRPTEK++ ++F+ AV+ALS LL LA+L +++R+R
Sbjct: 186 RRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQR 237
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 142 bits (359), Expect = 4e-34
Identities = 88/281 (31%), Positives = 142/281 (50%), Gaps = 13/281 (4%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ +N + T +G++W + + R++V+V+A V+ DE+ F+CNTLQPGC +VCYD F
Sbjct: 9 LLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQF 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLH-RGATLAALGPRRCPDPREPASGQRRCPRPF 128
P+SH+R W +Q + V P+ + +++V H + L DP +R
Sbjct: 69 FPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHIS 128
Query: 129 GERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCY 187
G Y+I ++ R L EA F + Y L+ G+ + C PC VDC+
Sbjct: 129 GTLWWT--------YVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
Query: 188 VSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQSGASGHAE 247
VSRPTEK++ +F+ A S + +L +A++V + R RR ++P RK SG
Sbjct: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS 240
Query: 248 GRRTDEEGGR---EEEGAPAPPGARAGGEGAGSPRRTSRVS 285
E + E++G+ R+ G GAG ++ R S
Sbjct: 241 PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCS 281
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 142 bits (359), Expect = 4e-34
Identities = 88/281 (31%), Positives = 142/281 (50%), Gaps = 13/281 (4%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ +N + T +G++W + + R++V+V+A V+ DE+ F+CNTLQPGC +VCYD F
Sbjct: 9 LLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCNSVCYDQF 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLH-RGATLAALGPRRCPDPREPASGQRRCPRPF 128
P+SH+R W +Q + V P+ + +++V H + L DP +R
Sbjct: 69 FPISHVRLWSLQLILVSTPALLVAMHVAHQQHIEKKMLRLEGHGDPLHLEEVKRHKVHIS 128
Query: 129 GERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCY 187
G Y+I ++ R L EA F + Y L+ G+ + C PC VDC+
Sbjct: 129 GTLWWT--------YVISVVFRLLFEAVFMYVFYLLYPGYAMVRLVKCDVYPCPNTVDCF 180
Query: 188 VSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGPPTSPSIRKQSGASGHAE 247
VSRPTEK++ +F+ A S + +L +A++V + R RR ++P RK SG
Sbjct: 181 VSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARRAQRRSNPPSRKGSGFGHRLS 240
Query: 248 GRRTDEEGGR---EEEGAPAPPGARAGGEGAGSPRRTSRVS 285
E + E++G+ R+ G GAG ++ R S
Sbjct: 241 PEYKQNEINKLLSEQDGSLKDILRRSPGTGAGLAEKSDRCS 281
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 142 bits (358), Expect = 5e-34
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 35/243 (14%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ ++ + T VGK+W + ++ R+++ + G +Y DEQ +FVCNT QPGC NVCYD F
Sbjct: 9 LLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAF 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATL----------------------AALG 107
+P+SH+RFW+ Q + V PS ++ Y +H+ A + AL
Sbjct: 69 APLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALE 128
Query: 108 PRRCPDPREP------------ASGQRRCPRPFGE-RGGLQVPDFSAGYIIHLLLRTLLE 154
+ +P + ++ P+P + R ++ Y++ LL RT+ E
Sbjct: 129 ETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFE 188
Query: 155 AAFGALHYFLFGFLAPKKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLA 214
F YFL+GF + C+R PC +DC++SRPTEK++ +L ++ V+ L LL +
Sbjct: 189 VGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIW 248
Query: 215 DLV 217
+++
Sbjct: 249 EML 251
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 142 bits (358), Expect = 5e-34
Identities = 75/243 (30%), Positives = 127/243 (52%), Gaps = 35/243 (14%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ ++ + T VGK+W + ++ R+++ + G +Y DEQ +FVCNT QPGC NVCYD F
Sbjct: 9 LLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCENVCYDAF 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATL----------------------AALG 107
+P+SH+RFW+ Q + V PS ++ Y +H+ A + AL
Sbjct: 69 APLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWKQHRALE 128
Query: 108 PRRCPDPREP------------ASGQRRCPRPFGE-RGGLQVPDFSAGYIIHLLLRTLLE 154
+ +P + ++ P+P + R ++ Y++ LL RT+ E
Sbjct: 129 ETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDGLMKIYVLQLLARTVFE 188
Query: 155 AAFGALHYFLFGFLAPKKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLA 214
F YFL+GF + C+R PC +DC++SRPTEK++ +L ++ V+ L LL +
Sbjct: 189 VGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGLCLLLNIW 248
Query: 215 DLV 217
+++
Sbjct: 249 EML 251
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 140 bits (354), Expect = 1e-33
Identities = 76/226 (33%), Positives = 122/226 (53%), Gaps = 14/226 (6%)
Query: 5 DLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANV 64
+LLG + ++ + TM+GK+W + + RMLV+ +A V+ DEQ F+CNT QPGC NV
Sbjct: 5 NLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPGCRNV 64
Query: 65 CYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPR--------E 116
CYD P+S +R+W++Q + V PS V+ + L+R L R R E
Sbjct: 65 CYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEEVEFE 124
Query: 117 PASGQRRCPR---PFGERGGLQVP---DFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAP 170
+RR + +R + P Y+IH+ R+++E F Y L+GF
Sbjct: 125 MPRDRRRLEQELCQLEKRKLNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLYGFHLE 184
Query: 171 KKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADL 216
F C PC ++DC+VSRPTEK++ +LF+ +++ +S L + ++
Sbjct: 185 PLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEI 230
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 135 bits (339), Expect = 8e-32
Identities = 77/218 (35%), Positives = 121/218 (55%), Gaps = 13/218 (5%)
Query: 14 LNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVS 73
+N + T +GK+W + + R++++V+A + V+ DEQE FVCNTLQPGC NVCYD F PVS
Sbjct: 13 VNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVS 72
Query: 74 HLRFWLIQGVCVLLPSAVFSVYVL---HRGATLAALGPRRCPDPREPASGQRRCPRPFGE 130
H+R W +Q + V P+ + +++V H G +R D ++ +++ R G
Sbjct: 73 HIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKR-NDFKDIEDIKKQKVRIEGS 131
Query: 131 RGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYVS 189
Y + R + EAAF + YFL+ G+ P C PC +VDC++S
Sbjct: 132 LWWT--------YTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFIS 183
Query: 190 RPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227
RPTEK++ +F+ + S + LL +A+L L + RR
Sbjct: 184 RPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 135 bits (339), Expect = 8e-32
Identities = 77/218 (35%), Positives = 121/218 (55%), Gaps = 13/218 (5%)
Query: 14 LNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVS 73
+N + T +GK+W + + R++++V+A + V+ DEQE FVCNTLQPGC NVCYD F PVS
Sbjct: 13 VNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVS 72
Query: 74 HLRFWLIQGVCVLLPSAVFSVYVL---HRGATLAALGPRRCPDPREPASGQRRCPRPFGE 130
H+R W +Q + V P+ + +++V H G +R D ++ +++ R G
Sbjct: 73 HIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKR-NDFKDIEDIKKQKVRIEGS 131
Query: 131 RGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYVS 189
Y + R + EAAF + YFL+ G+ P C PC +VDC++S
Sbjct: 132 LWWT--------YTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFIS 183
Query: 190 RPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227
RPTEK++ +F+ + S + LL +A+L L + RR
Sbjct: 184 RPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 135 bits (339), Expect = 8e-32
Identities = 77/218 (35%), Positives = 121/218 (55%), Gaps = 13/218 (5%)
Query: 14 LNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVS 73
+N + T +GK+W + + R++++V+A + V+ DEQE FVCNTLQPGC NVCYD F PVS
Sbjct: 13 VNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVS 72
Query: 74 HLRFWLIQGVCVLLPSAVFSVYVL---HRGATLAALGPRRCPDPREPASGQRRCPRPFGE 130
H+R W +Q + V P+ + +++V H G +R D ++ +++ R G
Sbjct: 73 HIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKR-NDFKDIEDIKKQKVRIEGS 131
Query: 131 RGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYVS 189
Y + R + EAAF + YFL+ G+ P C PC +VDC++S
Sbjct: 132 LWWT--------YTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFIS 183
Query: 190 RPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227
RPTEK++ +F+ + S + LL +A+L L + RR
Sbjct: 184 RPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 135 bits (339), Expect = 8e-32
Identities = 77/218 (35%), Positives = 121/218 (55%), Gaps = 13/218 (5%)
Query: 14 LNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVS 73
+N + T +GK+W + + R++++V+A + V+ DEQE FVCNTLQPGC NVCYD F PVS
Sbjct: 13 VNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVS 72
Query: 74 HLRFWLIQGVCVLLPSAVFSVYVL---HRGATLAALGPRRCPDPREPASGQRRCPRPFGE 130
H+R W +Q + V P+ + +++V H G +R D ++ +++ R G
Sbjct: 73 HIRLWALQLIFVSTPALLVAMHVAYYRHETTRKFRRGEKR-NDFKDIEDIKKQKVRIEGS 131
Query: 131 RGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYVS 189
Y + R + EAAF + YFL+ G+ P C PC +VDC++S
Sbjct: 132 LWWT--------YTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFIS 183
Query: 190 RPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRR 227
RPTEK++ +F+ + S + LL +A+L L + RR
Sbjct: 184 RPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFRR 221
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 131 bits (329), Expect = 1e-30
Identities = 73/214 (34%), Positives = 114/214 (53%), Gaps = 15/214 (7%)
Query: 14 LNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVS 73
+N + T +GK+W + + R++++V+A + V+ DEQ FVCNTLQPGC NVCYD + P+S
Sbjct: 13 VNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCKNVCYDHYFPIS 72
Query: 74 HLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFGERGG 133
H+R W +Q + V P+ + +++V + RR R+ G+ + E
Sbjct: 73 HIRLWALQLIFVSTPALLVAMHVAY----------RRHEKKRKFIKGEIKSEFKDIEEIK 122
Query: 134 LQVPDFSAG----YIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYV 188
Q Y + R + EAAF + Y ++ GF + C PC VDC+V
Sbjct: 123 TQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGFSMQRLVKCNAWPCPNTVDCFV 182
Query: 189 SRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRR 222
SRPTEK++ +F+ AVS + LL + +L L R
Sbjct: 183 SRPTEKTVFTVFMIAVSGICILLNVTELCYLLIR 216
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 130 bits (326), Expect = 2e-30
Identities = 100/378 (26%), Positives = 162/378 (42%), Gaps = 38/378 (10%)
Query: 7 LGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCY 66
LG L+ + T GK+W + + R+L++ A + DEQ F CNT QPGC NVCY
Sbjct: 7 LGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPGCENVCY 66
Query: 67 DVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPR 126
D P+SH+RFW++Q + V +P+ ++ +V + L + E Q
Sbjct: 67 DKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKE----EELKVAQTDGVN 122
Query: 127 PFGERGGLQVPDFSAG----------------YIIHLLLRTLLEAAFGALHYFLFGFLAP 170
+++ F G YII +L +++ E AF + ++++GF
Sbjct: 123 VDMHLKQIEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIYGFSLS 182
Query: 171 KKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGP 230
+ C R PC VDC++SRPTEK++ ++F+ VS +S L + +L + ++ R
Sbjct: 183 AVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVKDRVKG 242
Query: 231 PTSPSIRKQSGASGHAE---GRRTDEEGGREEEGAPAPPGARAGGEGAGSPRRTSRVSGH 287
+ P SGA A+ ++ G AP P + G + R S +
Sbjct: 243 KSDP-YHATSGALSPAKDCGSQKYAYFNGCSSPTAPLSPMSPPGYKLVTGDRNNSSCRNY 301
Query: 288 TKIPDEDESEVTSSASEKLGR----------QPRGRPHREAAQDPRGSGSEEQPSA---- 333
K E S+ ++G+ QP P +G E QP A
Sbjct: 302 NKQASEQNWANYSAEQNRMGQAGSTISNSHAQPFDFPDDNQNSKKLAAGHELQPLAIVDQ 361
Query: 334 APSRLAAPPSCSSLQPPD 351
PS A+ + S +P D
Sbjct: 362 RPSSRASSRASSRPRPDD 379
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 126 bits (317), Expect = 3e-29
Identities = 72/222 (32%), Positives = 117/222 (52%), Gaps = 12/222 (5%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ +N T++ ++W + + R+LV V+A V+ DEQ+ FVCNT QPGC NVCYD F
Sbjct: 9 LLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCPNVCYDEF 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFG 129
PVSH+R W +Q + V PS + ++V +R + P+ +
Sbjct: 69 FPVSHVRLWALQLILVTCPSLLVVMHVAYREERERKHHLKHGPNAPSLYDNLSK------ 122
Query: 130 ERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYV 188
+RGGL Y++ L+ + ++A F + + L+ + P+ C+ PC VDCY+
Sbjct: 123 KRGGLWWT-----YLLSLIFKAAVDAGFLYIFHRLYKDYDMPRVVACSVEPCPHTVDCYI 177
Query: 189 SRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRRRPGP 230
SRPTEK + F+ +A+ LL L+++ + +R GP
Sbjct: 178 SRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEIFGP 219
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 126 bits (317), Expect = 3e-29
Identities = 71/215 (33%), Positives = 116/215 (53%), Gaps = 12/215 (5%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ +N T G++W L + R+LV ++ V+ D+ + F CNT QPGC+NVC+D F
Sbjct: 9 LLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCSNVCFDEF 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFG 129
PVSH+R W +Q + V PS + ++V +R + +R + SG R P
Sbjct: 69 FPVSHVRLWALQLILVTCPSLLVVMHVAYR-----EVQEKRHREAHGENSG-RLYLNPGK 122
Query: 130 ERGGLQVPDFSAGYIIHLLLRTLLEAAF-GALHYFLFGFLAPKKFPCTRPPCTGVVDCYV 188
+RGGL Y+ L+ + ++ AF H F ++ P C PC +VDC++
Sbjct: 123 KRGGLWWT-----YVCSLVFKASVDIAFLYVFHSFYPKYILPPVVKCHADPCPNIVDCFI 177
Query: 189 SRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRR 223
S+P+EK++ LF+ A +A+ LL L +L+ + +R
Sbjct: 178 SKPSEKNIFTLFMVATAAICILLNLVELIYLVSKR 212
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 122 bits (307), Expect = 4e-28
Identities = 70/208 (33%), Positives = 107/208 (51%), Gaps = 19/208 (9%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ +N T G +W + + R+LV ++A V++DEQ+ F CN+ QPGC NVC+D F
Sbjct: 9 LLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKNVCFDDF 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFG 129
P+S +R W +Q + V PS + ++V + + RE ++ P
Sbjct: 69 FPISQVRLWALQLIMVSTPSLLVVLHVAYH-------------EGREKRHRKKLYVSPGT 115
Query: 130 ERGGLQVPDFSAGYIIHLLLRTLLEAAFGALHYFLF-GFLAPKKFPCTRPPCTGVVDCYV 188
GGL Y+I L+++T E F L Y L+ GF P C PC VDC++
Sbjct: 116 MDGGLWY-----AYLISLIVKTGFEIGFLVLFYKLYDGFSVPYLIKCDLKPCPNTVDCFI 170
Query: 189 SRPTEKSLLMLFLWAVSALSFLLGLADL 216
S+PTEK++ +LFL S L +L +L
Sbjct: 171 SKPTEKTIFILFLVITSCLCIVLNFIEL 198
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 122 bits (306), Expect = 5e-28
Identities = 69/204 (33%), Positives = 101/204 (49%), Gaps = 15/204 (7%)
Query: 19 TMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVSHLRFW 78
T VG+L + + R++++ +G VY DEQ FVC+T QPGC C+D F P+S LRFW
Sbjct: 18 TPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAFHPLSPLRFW 77
Query: 79 LIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQRRCPRPFGERGGLQVPD 138
+ Q + V +PSA++ + L+ L G+ G G VP
Sbjct: 78 VFQVILVAVPSALYMGFTLYHVIWHWELS----------GKGKEEETLIQGREGNTDVPG 127
Query: 139 FSA-----GYIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCTGVVDCYVSRPTE 193
+ Y+ L R +LE A L Y L+GF P F C R PC G + C +SRP+E
Sbjct: 128 AGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSFACRREPCLGSITCNLSRPSE 187
Query: 194 KSLLMLFLWAVSALSFLLGLADLV 217
K++ + ++ VS L +LV
Sbjct: 188 KTIFLKTMFGVSGFCLLFTFLELV 211
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 122 bits (305), Expect = 7e-28
Identities = 82/271 (30%), Positives = 129/271 (47%), Gaps = 29/271 (10%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ +N T G++W + + R+LV V+A V+ DEQ+ F CNT QPGC NVCYD +
Sbjct: 9 LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQR---RCPR 126
P+S++R W +Q + V PS + ++V +R + RE Q+ +C +
Sbjct: 69 FPISNIRLWALQLIFVTCPSLLVILHVAYR-------------EERERRHRQKHGDQCAK 115
Query: 127 PFGERGGLQVPDFSAGYIIHLLLRTLLEAAF-GALHYFLFGFLAPKKFPCTR-PPCTGVV 184
+ + G + Y+ L+ + ++E F LH GF P+ C PC +V
Sbjct: 116 LY-DNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIV 174
Query: 185 DCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRR-------RPGPPTSPSIR 237
DCY++RPTEK + F+ SA+ +L + +L + R+ R R G S S
Sbjct: 175 DCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSAS 234
Query: 238 KQSGASGH---AEGRRTDEEGGREEEGAPAP 265
+ S H E D + G + A AP
Sbjct: 235 RASTCRCHHKLVEAGEVDPDPGNNKLQASAP 265
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 122 bits (305), Expect = 7e-28
Identities = 82/271 (30%), Positives = 129/271 (47%), Gaps = 29/271 (10%)
Query: 10 LIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVF 69
L+ +N T G++W + + R+LV V+A V+ DEQ+ F CNT QPGC NVCYD +
Sbjct: 9 LLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNY 68
Query: 70 SPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASGQR---RCPR 126
P+S++R W +Q + V PS + ++V +R + RE Q+ +C +
Sbjct: 69 FPISNIRLWALQLIFVTCPSLLVILHVAYR-------------EERERRHRQKHGDQCAK 115
Query: 127 PFGERGGLQVPDFSAGYIIHLLLRTLLEAAF-GALHYFLFGFLAPKKFPCTR-PPCTGVV 184
+ + G + Y+ L+ + ++E F LH GF P+ C PC +V
Sbjct: 116 LY-DNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIV 174
Query: 185 DCYVSRPTEKSLLMLFLWAVSALSFLLGLADLVCSLRRRMRR-------RPGPPTSPSIR 237
DCY++RPTEK + F+ SA+ +L + +L + R+ R R G S S
Sbjct: 175 DCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSAS 234
Query: 238 KQSGASGH---AEGRRTDEEGGREEEGAPAP 265
+ S H E D + G + A AP
Sbjct: 235 RASTCRCHHKLVEAGEVDPDPGNNKLQASAP 265
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 92.4 bits (228), Expect = 6e-19
Identities = 37/83 (44%), Positives = 54/83 (65%)
Query: 19 TMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANVCYDVFSPVSHLRFW 78
TM+G++ + ++ R+L++ + G VY DEQ FVCNTLQPGC CYD P+SH+R+W
Sbjct: 20 TMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQPGCNQACYDRAFPISHIRYW 79
Query: 79 LIQGVCVLLPSAVFSVYVLHRGA 101
+ Q + V PS F Y +H+ A
Sbjct: 80 VFQIIMVCTPSLCFITYSVHQSA 102
Score = 76.3 bits (186), Expect = 4e-14
Identities = 35/74 (47%), Positives = 49/74 (66%)
Query: 143 YIIHLLLRTLLEAAFGALHYFLFGFLAPKKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLW 202
YII ++ R LE F YFL+GF P + C R PC V+CYVSRPTEK++ ++F++
Sbjct: 199 YIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKEVECYVSRPTEKTVFLVFMF 258
Query: 203 AVSALSFLLGLADL 216
AVS + +L LA+L
Sbjct: 259 AVSGICVVLNLAEL 272
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 84.7 bits (208), Expect = 1e-16
Identities = 46/127 (36%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Query: 1 MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPG 60
M G L +L+ + + T VG+L F + + R++++ +G VY DEQ FVC+T QPG
Sbjct: 19 MCGRFLRWWLLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 78
Query: 61 CANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASG 120
C C+D F P+S LRFW+ Q + V +PS ++ Y P RC P+
Sbjct: 79 CKAACFDAFHPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRC----GPSEV 134
Query: 121 QRRCPRP 127
R PRP
Sbjct: 135 LERAPRP 141
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 84.7 bits (208), Expect = 1e-16
Identities = 46/127 (36%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Query: 1 MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPG 60
M G L +L+ + + T VG+L F + + R++++ +G VY DEQ FVC+T QPG
Sbjct: 19 MCGRFLRWWLLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 78
Query: 61 CANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASG 120
C C+D F P+S LRFW+ Q + V +PS ++ Y P RC P+
Sbjct: 79 CKAACFDAFHPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRC----GPSEV 134
Query: 121 QRRCPRP 127
R PRP
Sbjct: 135 LERAPRP 141
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 84.7 bits (208), Expect = 1e-16
Identities = 46/127 (36%), Positives = 67/127 (52%), Gaps = 4/127 (3%)
Query: 1 MEGVDLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPG 60
M G L +L+ + + T VG+L F + + R++++ +G VY DEQ FVC+T QPG
Sbjct: 19 MCGRFLRWWLLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPG 78
Query: 61 CANVCYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHRGATLAALGPRRCPDPREPASG 120
C C+D F P+S LRFW+ Q + V +PS ++ Y P RC P+
Sbjct: 79 CKAACFDAFHPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQYREPPRC----GPSEV 134
Query: 121 QRRCPRP 127
R PRP
Sbjct: 135 LERAPRP 141
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,465,259
Number of Sequences: 37866
Number of extensions: 1111111
Number of successful extensions: 12020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 925
Number of HSP's that attempted gapping in prelim test: 9077
Number of HSP's gapped (non-prelim): 3396
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.