BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|14550405 postreplication repair protein hRAD18p [Homo sapiens] (495 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|14550405 postreplication repair protein hRAD18p [Homo sapiens] 983 0.0 gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 53 6e-07 gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 52 2e-06 gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 52 2e-06 gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 51 3e-06 gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens] 50 5e-06 gi|109240538 polycomb group ring finger 1 [Homo sapiens] 50 5e-06 gi|19923717 deltex 3-like [Homo sapiens] 49 1e-05 gi|52487176 tripartite motif-containing 37 protein [Homo sapiens] 47 3e-05 gi|15147333 tripartite motif-containing 37 protein [Homo sapiens] 47 3e-05 gi|31542779 tripartite motif family-like 1 [Homo sapiens] 47 4e-05 gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 47 5e-05 gi|6005964 ring finger protein 110 [Homo sapiens] 46 7e-05 gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens] 45 2e-04 gi|21314654 ring finger protein 139 [Homo sapiens] 45 2e-04 gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens] 45 2e-04 gi|33946313 ninein isoform 4 [Homo sapiens] 44 3e-04 gi|33946321 ninein isoform 5 [Homo sapiens] 44 3e-04 gi|148536871 ninein isoform 1 [Homo sapiens] 44 3e-04 gi|148536869 ninein isoform 2 [Homo sapiens] 44 3e-04 gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 44 3e-04 gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 44 3e-04 gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 44 3e-04 gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 44 3e-04 gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] 44 3e-04 gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] 44 3e-04 gi|7705415 hook homolog 1 [Homo sapiens] 44 3e-04 gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens] 44 3e-04 gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] 44 3e-04 gi|223890259 midline 2 isoform 2 [Homo sapiens] 44 4e-04 >gi|14550405 postreplication repair protein hRAD18p [Homo sapiens] Length = 495 Score = 983 bits (2542), Expect = 0.0 Identities = 495/495 (100%), Positives = 495/495 (100%) Query: 1 MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQC 60 MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQC Sbjct: 1 MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQC 60 Query: 61 PTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPV 120 PTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPV Sbjct: 61 PTCCVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPV 120 Query: 121 ASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAP 180 ASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAP Sbjct: 121 ASRQSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAP 180 Query: 181 DPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKR 240 DPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKR Sbjct: 181 DPSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKR 240 Query: 241 KPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEI 300 KPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEI Sbjct: 241 KPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEI 300 Query: 301 VQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKG 360 VQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKG Sbjct: 301 VQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKG 360 Query: 361 YKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREED 420 YKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREED Sbjct: 361 YKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREED 420 Query: 421 SSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRA 480 SSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRA Sbjct: 421 SSSCIDIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEASHKNDLQDTEISPRQNRRTRA 480 Query: 481 AESAEIEPRNKRNRN 495 AESAEIEPRNKRNRN Sbjct: 481 AESAEIEPRNKRNRN 495 >gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] Length = 1411 Score = 53.1 bits (126), Expect = 6e-07 Identities = 76/369 (20%), Positives = 159/369 (43%), Gaps = 53/369 (14%) Query: 135 NFLIREMSGSTSELLIK-ENKSKFSPQKEASPAAKTKETRSVEEIAPDPSEAKRPEPPST 193 N + E S+L I+ + K++ EA+ A+ + ++ + A + + K+ E Sbjct: 627 NSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKI 686 Query: 194 ST-LKQVT-KVDCPVCGVNIPESHINKHLDSCLSREEKKESLRSSVHKRKPLPKTVYNLL 251 +T L QVT K+ + ESH+ ++ + LS E+K E L + Sbjct: 687 TTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQI-------------- 732 Query: 252 SDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIENIEKTR 311 KKL+ L ++ +K+Q ++ Q+ N + + + ++ E E + TR Sbjct: 733 ------KKLEADSLEVKASKEQALQDLQQ-QRQLNTDLELRATELSKQLEMEKEIVSSTR 785 Query: 312 MRLE-ASKLNESV-MVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQ 369 + L+ S+ ES+ TK + EK+I K +F+ L + + ++++ Q Sbjct: 786 LDLQKKSEALESIKQKLTKQEEEKQI----------LKQDFETLSQETKIQHEELNNRIQ 835 Query: 370 KTVT-ITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLDSPEELEPDREEDSSSCIDIQ 428 TVT + K E L + +D ++ V++ SK E E + ++ ++ +D++ Sbjct: 836 TTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSK----SEFEKENQKGKAAILDLE 891 Query: 429 EVLSSSESDSCNSSSSDI-----IRDLLEEEEAWEASHK-----NDLQDTEISPRQNRRT 478 + + + + ++ LE+E+ EASH+ N +Q+ I + + Sbjct: 892 KTCKELKHQLQVQMENTLKEQKELKKSLEKEK--EASHQLKLELNSMQEQLIQAQNTLKQ 949 Query: 479 RAAESAEIE 487 E +++ Sbjct: 950 NEKEEQQLQ 958 Score = 33.1 bits (74), Expect = 0.60 Identities = 63/279 (22%), Positives = 113/279 (40%), Gaps = 55/279 (19%) Query: 121 ASRQSLKQG--SRLMDNFLIREMSGSTSELL------IKENKSKFSPQKEASPAAKTKET 172 A QSL+Q +NF I++M + I + KSK+ ++ AA+ K T Sbjct: 135 AELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVT 194 Query: 173 RSVEEIAPDPSE--------AKRPEPPSTSTL-KQVTKVDCPVCGVNIP-ESHINKHLDS 222 R EE+ + + +RP + L K++ +V + + + E K D Sbjct: 195 RLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDE 254 Query: 223 C-------LSREEKKESLRSS-----------VHKRKPLPKTVYNL------LSDRDLKK 258 C S E LRS V + + L +V L L++ LKK Sbjct: 255 CKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKK 314 Query: 259 KLKEHGLSIQGNKQQLIKRH-QEFVHMYNAQCDALHPKSAAEIVQEIENIEKTRMRLEAS 317 + L + N++ + K++ Q +H + C L + +A R+ +E S Sbjct: 315 EQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSA------SETSLHRIHVELS 368 Query: 318 KLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQLLVDQ 356 + E+ + ++E+ E+ +KY+ K+EF+ L Q Sbjct: 369 EKGEAT-----QKLKEELSEVETKYQHL-KAEFKQLQQQ 401 Score = 31.2 bits (69), Expect = 2.3 Identities = 51/304 (16%), Positives = 139/304 (45%), Gaps = 51/304 (16%) Query: 123 RQSLKQGSRLMDNFLI-REMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAPD 181 ++ L Q LMDN + RE + K+ +S+++ + +++ + +E+A Sbjct: 227 KKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVY 286 Query: 182 PSEAKRPEPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDSCLSREE------KKESLRS 235 E ++ + S++ ++T+ + + E+ + K D E+ K+++++ Sbjct: 287 VQELQKLK----SSVNELTQKN-----QTLTENLLKKEQDYTKLEEKHNEESVSKKNIQA 337 Query: 236 SVHKRKPLPKTVYNLLSDRD-----LKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCD 290 ++H++ + + + LS + + +L E G + Q K++L + ++ H+ Sbjct: 338 TLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHL------ 391 Query: 291 ALHPKSAAEIVQEIENIEKTRMRL--EASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKS 348 ++ Q+ E E+ ++L E ++L+ ++ +TE+++ E H + +++ + Sbjct: 392 ---KAEFKQLQQQREEKEQHGLQLQSEINQLHSKLL-----ETERQLGEAHGRLKEQRQL 443 Query: 349 EFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSKLD 408 + L+D+ +++A + K + E++ EK++ N T + + ++K Sbjct: 444 SSEKLMDKE----QQVADLQLKLSRL--EEQLKEKVT--------NSTELQHQLDKTKQQ 489 Query: 409 SPEE 412 E+ Sbjct: 490 HQEQ 493 >gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens] Length = 1758 Score = 51.6 bits (122), Expect = 2e-06 Identities = 45/181 (24%), Positives = 70/181 (38%), Gaps = 20/181 (11%) Query: 19 IDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFL--SYKTQCPTCCVTVTEPD-LKNN 75 I D L C IC + A++IP C ++YC CIR L S + CPTC PD L N Sbjct: 253 IPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQNDVSPDALIAN 312 Query: 76 RILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPVASRQSLKQGSRLMDN 135 + L + V + + + + P P + L + P+ +Q LM Sbjct: 313 KFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIP 372 Query: 136 FLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAPDPSEAKRPEPPSTST 195 + S + N+S +P ++ +PS A P P T+T Sbjct: 373 VTSSSTHPAPSISSLTSNQSSLAP-----------------PVSGNPSSAPAPVPDITAT 415 Query: 196 L 196 + Sbjct: 416 V 416 >gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens] Length = 1792 Score = 51.6 bits (122), Expect = 2e-06 Identities = 45/181 (24%), Positives = 70/181 (38%), Gaps = 20/181 (11%) Query: 19 IDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFL--SYKTQCPTCCVTVTEPD-LKNN 75 I D L C IC + A++IP C ++YC CIR L S + CPTC PD L N Sbjct: 253 IPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHTCPTCHQNDVSPDALIAN 312 Query: 76 RILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPVASRQSLKQGSRLMDN 135 + L + V + + + + P P + L + P+ +Q LM Sbjct: 313 KFLRQAVNNFKNETGYTKRLRKQLPPPPPPIPPPRPLIQRNLQPLMRSPISRQQDPLMIP 372 Query: 136 FLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAPDPSEAKRPEPPSTST 195 + S + N+S +P ++ +PS A P P T+T Sbjct: 373 VTSSSTHPAPSISSLTSNQSSLAP-----------------PVSGNPSSAPAPVPDITAT 415 Query: 196 L 196 + Sbjct: 416 V 416 >gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo sapiens] Length = 1940 Score = 50.8 bits (120), Expect = 3e-06 Identities = 48/214 (22%), Positives = 92/214 (42%), Gaps = 29/214 (13%) Query: 255 DLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCDALHPKSAAEIVQEIENIEKTRMRL 314 +L KK + L ++ + ++ +H+ V A H S AE+ ++I+N+++ + +L Sbjct: 1163 ELNKKREAEFLKLRRDLEEATLQHEAMV----AALRKKHADSVAELGEQIDNLQRVKQKL 1218 Query: 315 EASKLNESVMVFTKDQTEKEIDEIHSKYRKKHKSEFQL------LVDQARKGYKKIAGMS 368 E K + + EID++ S KS+ L L DQ + K + Sbjct: 1219 EKE----------KSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQ 1268 Query: 369 QKTVTITKEDESTEKLSSVCMGQEDNMTSVTNHFSQSK---LDSPEELEPDREEDSSSCI 425 + +T + + + Q + S+ + S+SK EEL+ EE++ + Sbjct: 1269 RSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKN 1328 Query: 426 DIQEVLSSSESDSCNSSSSDIIRDLLEEEEAWEA 459 + L SS D D++R+ EEE+ +A Sbjct: 1329 ALAHALQSSRHD------CDLLREQYEEEQEGKA 1356 >gi|157266328 BRCA1 associated RING domain 1 [Homo sapiens] Length = 777 Score = 50.1 bits (118), Expect = 5e-06 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 2/92 (2%) Query: 1 MDSLAESRWPPGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQC 60 M+ W A + ++ LLRC C + + C H +CS C+ + T C Sbjct: 26 MEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIG--TGC 83 Query: 61 PTCCVTVTEPDLKNNRILDELVKSLNFARNHL 92 P C DLK NR LD +++ + RN L Sbjct: 84 PVCYTPAWIQDLKINRQLDSMIQLCSKLRNLL 115 >gi|109240538 polycomb group ring finger 1 [Homo sapiens] Length = 259 Score = 50.1 bits (118), Expect = 5e-06 Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 4/74 (5%) Query: 16 MKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTV--TEP--D 71 +K +++ + C +C YF A I +C H +C CI K+L CP C + + T+P + Sbjct: 38 IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLN 97 Query: 72 LKNNRILDELVKSL 85 LK +R++ ++V L Sbjct: 98 LKLDRVMQDIVYKL 111 >gi|19923717 deltex 3-like [Homo sapiens] Length = 740 Score = 48.9 bits (115), Expect = 1e-05 Identities = 17/39 (43%), Positives = 25/39 (64%) Query: 25 CGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTC 63 C IC + + ++P+C H +C+ CI K +SYK CPTC Sbjct: 561 CVICMDTISNKKVLPKCKHEFCAPCINKAMSYKPICPTC 599 >gi|52487176 tripartite motif-containing 37 protein [Homo sapiens] Length = 964 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Query: 16 MKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLS-YKTQCPTCCVTVTEPDLKN 74 +++I ++ RC IC E A + P CS C CIR++L+ + QCP C + +L N Sbjct: 6 VESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVN 65 Query: 75 NRILDELVKSLN 86 R +E+ + L+ Sbjct: 66 CRWAEEVTQQLD 77 >gi|15147333 tripartite motif-containing 37 protein [Homo sapiens] Length = 964 Score = 47.4 bits (111), Expect = 3e-05 Identities = 24/72 (33%), Positives = 40/72 (55%), Gaps = 1/72 (1%) Query: 16 MKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLS-YKTQCPTCCVTVTEPDLKN 74 +++I ++ RC IC E A + P CS C CIR++L+ + QCP C + +L N Sbjct: 6 VESIAEVFRCFICMEKLRDARLCPHCSKLCCFSCIRRWLTEQRAQCPHCRAPLQLRELVN 65 Query: 75 NRILDELVKSLN 86 R +E+ + L+ Sbjct: 66 CRWAEEVTQQLD 77 >gi|31542779 tripartite motif family-like 1 [Homo sapiens] Length = 468 Score = 47.0 bits (110), Expect = 4e-05 Identities = 27/102 (26%), Positives = 52/102 (50%), Gaps = 4/102 (3%) Query: 15 VMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLC-IRKFLSYKT--QCPTCCVTVTEPD 71 +M+ + + L C IC +YF+ + + +C H++C +C +R + + T CP C T+ P Sbjct: 6 LMENLREELTCFICLDYFS-SPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPH 64 Query: 72 LKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLA 113 ++N L L R+ +LQ E + +++K L+ Sbjct: 65 FQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALS 106 >gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] Length = 485 Score = 46.6 bits (109), Expect = 5e-05 Identities = 18/45 (40%), Positives = 30/45 (66%), Gaps = 1/45 (2%) Query: 19 IDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTC 63 +++ L+C IC EYF I + C+H++CS CI +++ K +CP C Sbjct: 397 LENELQCIICSEYF-IEAVTLNCAHSFCSYCINEWMKRKIECPIC 440 >gi|6005964 ring finger protein 110 [Homo sapiens] Length = 344 Score = 46.2 bits (108), Expect = 7e-05 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Query: 23 LRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTV--TEP--DLKNNRIL 78 L C +C YF A I +C H++C CI ++L CP C V V T P +++++ L Sbjct: 16 LMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDKTL 75 Query: 79 DELVKSL 85 ++V L Sbjct: 76 QDIVYKL 82 >gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens] Length = 326 Score = 45.1 bits (105), Expect = 2e-04 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 4/67 (5%) Query: 23 LRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTV--TEP--DLKNNRIL 78 L C +C YF A I +C H++C CI ++L CP C V V T P ++++++ L Sbjct: 16 LMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTL 75 Query: 79 DELVKSL 85 ++V L Sbjct: 76 QDIVYKL 82 >gi|21314654 ring finger protein 139 [Homo sapiens] Length = 664 Score = 44.7 bits (104), Expect = 2e-04 Identities = 22/61 (36%), Positives = 36/61 (59%), Gaps = 3/61 (4%) Query: 16 MKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTV-TEPDLKN 74 ++ I+D+ C IC+ F + I C+H + +LC+RK+L + CP C V E D+K+ Sbjct: 540 LQEINDV--CAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIKD 597 Query: 75 N 75 N Sbjct: 598 N 598 >gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens] Length = 500 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/78 (29%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Query: 11 PGLAVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKF---LSYKTQCPTCCVTV 67 P V++ I L C +C ++F +++ C HN+C CI+ F + +T CP C + Sbjct: 27 PSKVVIQDITMELHCPLCNDWFRDPLML-SCGHNFCEACIQDFWRLQAKETFCPECKMLC 85 Query: 68 TEPDLKNNRILDELVKSL 85 + N +LD+LV+ + Sbjct: 86 QYNNCTFNPVLDKLVEKI 103 >gi|33946313 ninein isoform 4 [Homo sapiens] Length = 2096 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/271 (18%), Positives = 116/271 (42%), Gaps = 28/271 (10%) Query: 219 HLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKR- 277 H ++ EE+K+ L+ + + K + L + +LK +L + S + ++ L Sbjct: 696 HHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSA 755 Query: 278 -HQEFVHMYNAQCDALHPKSAAEIVQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEID 336 +E V + + H + +V++ +EK +R E + ++ + +++ E E + Sbjct: 756 WTEEKVRGLTQELEQFHQEQLTSLVEK-HTLEKEELRKELLEKHQRELQEGREKMETECN 814 Query: 337 EIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEK---------LSSV 387 S+ + +S+ Q + ++ + + G ++ + +E + EK L+ Sbjct: 815 RRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQE 874 Query: 388 CMGQEDNMTSVTNHFSQSKLDSPEELE----PDREEDSSSCIDIQEVLSSSE-----SDS 438 C ++ + + L +E E +E +S ++ Q++L E S++ Sbjct: 875 CAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSET 934 Query: 439 CNSSSSDIIRDLLEEEEAWEASHKNDLQDTE 469 S SD I +L ++SHK +L++ E Sbjct: 935 QQSLLSDQILEL-------KSSHKRELRERE 958 >gi|33946321 ninein isoform 5 [Homo sapiens] Length = 2090 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/271 (18%), Positives = 116/271 (42%), Gaps = 28/271 (10%) Query: 219 HLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKR- 277 H ++ EE+K+ L+ + + K + L + +LK +L + S + ++ L Sbjct: 690 HHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSA 749 Query: 278 -HQEFVHMYNAQCDALHPKSAAEIVQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEID 336 +E V + + H + +V++ +EK +R E + ++ + +++ E E + Sbjct: 750 WTEEKVRGLTQELEQFHQEQLTSLVEK-HTLEKEELRKELLEKHQRELQEGREKMETECN 808 Query: 337 EIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEK---------LSSV 387 S+ + +S+ Q + ++ + + G ++ + +E + EK L+ Sbjct: 809 RRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQE 868 Query: 388 CMGQEDNMTSVTNHFSQSKLDSPEELE----PDREEDSSSCIDIQEVLSSSE-----SDS 438 C ++ + + L +E E +E +S ++ Q++L E S++ Sbjct: 869 CAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSET 928 Query: 439 CNSSSSDIIRDLLEEEEAWEASHKNDLQDTE 469 S SD I +L ++SHK +L++ E Sbjct: 929 QQSLLSDQILEL-------KSSHKRELRERE 952 >gi|148536871 ninein isoform 1 [Homo sapiens] Length = 2046 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/271 (18%), Positives = 116/271 (42%), Gaps = 28/271 (10%) Query: 219 HLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKR- 277 H ++ EE+K+ L+ + + K + L + +LK +L + S + ++ L Sbjct: 690 HHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSA 749 Query: 278 -HQEFVHMYNAQCDALHPKSAAEIVQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEID 336 +E V + + H + +V++ +EK +R E + ++ + +++ E E + Sbjct: 750 WTEEKVRGLTQELEQFHQEQLTSLVEK-HTLEKEELRKELLEKHQRELQEGREKMETECN 808 Query: 337 EIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEK---------LSSV 387 S+ + +S+ Q + ++ + + G ++ + +E + EK L+ Sbjct: 809 RRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQE 868 Query: 388 CMGQEDNMTSVTNHFSQSKLDSPEELE----PDREEDSSSCIDIQEVLSSSE-----SDS 438 C ++ + + L +E E +E +S ++ Q++L E S++ Sbjct: 869 CAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSET 928 Query: 439 CNSSSSDIIRDLLEEEEAWEASHKNDLQDTE 469 S SD I +L ++SHK +L++ E Sbjct: 929 QQSLLSDQILEL-------KSSHKRELRERE 952 >gi|148536869 ninein isoform 2 [Homo sapiens] Length = 2133 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/271 (18%), Positives = 116/271 (42%), Gaps = 28/271 (10%) Query: 219 HLDSCLSREEKKESLRSSVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKR- 277 H ++ EE+K+ L+ + + K + L + +LK +L + S + ++ L Sbjct: 690 HHEATCRHEEEKKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSA 749 Query: 278 -HQEFVHMYNAQCDALHPKSAAEIVQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEID 336 +E V + + H + +V++ +EK +R E + ++ + +++ E E + Sbjct: 750 WTEEKVRGLTQELEQFHQEQLTSLVEK-HTLEKEELRKELLEKHQRELQEGREKMETECN 808 Query: 337 EIHSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITKEDESTEK---------LSSV 387 S+ + +S+ Q + ++ + + G ++ + +E + EK L+ Sbjct: 809 RRTSQIEAQFQSDCQKVTERCESALQSLEGRYRQELKDLQEQQREEKSQWEFEKDELTQE 868 Query: 388 CMGQEDNMTSVTNHFSQSKLDSPEELE----PDREEDSSSCIDIQEVLSSSE-----SDS 438 C ++ + + L +E E +E +S ++ Q++L E S++ Sbjct: 869 CAEAQELLKETLKREKTTSLVLTQEREMLEKTYKEHLNSMVVERQQLLQDLEDLRNVSET 928 Query: 439 CNSSSSDIIRDLLEEEEAWEASHKNDLQDTE 469 S SD I +L ++SHK +L++ E Sbjct: 929 QQSLLSDQILEL-------KSSHKRELRERE 952 >gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] Length = 1884 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 15 VMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYK---TQCPTCCVTVTEPD 71 V+ + +L C IC E + +C H +C C+ K L+ K +QCP C +T+ Sbjct: 14 VINAMQKILECPICLELIK-EPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRS 72 Query: 72 LKNNRILDELVKSL 85 L+ + +LV+ L Sbjct: 73 LQESTRFSQLVEEL 86 >gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] Length = 699 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 15 VMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYK---TQCPTCCVTVTEPD 71 V+ + +L C IC E + +C H +C C+ K L+ K +QCP C +T+ Sbjct: 14 VINAMQKILECPICLELIK-EPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRS 72 Query: 72 LKNNRILDELVKSL 85 L+ + +LV+ L Sbjct: 73 LQESTRFSQLVEEL 86 >gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] Length = 759 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 15 VMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYK---TQCPTCCVTVTEPD 71 V+ + +L C IC E + +C H +C C+ K L+ K +QCP C +T+ Sbjct: 14 VINAMQKILECPICLELIK-EPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRS 72 Query: 72 LKNNRILDELVKSL 85 L+ + +LV+ L Sbjct: 73 LQESTRFSQLVEEL 86 >gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] Length = 1863 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 15 VMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYK---TQCPTCCVTVTEPD 71 V+ + +L C IC E + +C H +C C+ K L+ K +QCP C +T+ Sbjct: 14 VINAMQKILECPICLELIK-EPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRS 72 Query: 72 LKNNRILDELVKSL 85 L+ + +LV+ L Sbjct: 73 LQESTRFSQLVEEL 86 >gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens] Length = 488 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 4/73 (5%) Query: 14 AVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKF---LSYKTQCPTCCVTVTEP 70 A ++ + C +C EY +II +C HN+C CI ++ L CP C T Sbjct: 18 AALENLQVEASCSVCLEYLKEPVII-ECGHNFCKACITRWWEDLERDFPCPVCRKTSRYR 76 Query: 71 DLKNNRILDELVK 83 L+ NR L +V+ Sbjct: 77 SLRPNRQLGSMVE 89 >gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens] Length = 518 Score = 43.9 bits (102), Expect = 3e-04 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 4/73 (5%) Query: 14 AVMKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKF---LSYKTQCPTCCVTVTEP 70 A ++ + C +C EY +II +C HN+C CI ++ L CP C T Sbjct: 18 AALENLQVEASCSVCLEYLKEPVII-ECGHNFCKACITRWWEDLERDFPCPVCRKTSRYR 76 Query: 71 DLKNNRILDELVK 83 L+ NR L +V+ Sbjct: 77 SLRPNRQLGSMVE 89 >gi|7705415 hook homolog 1 [Homo sapiens] Length = 728 Score = 43.9 bits (102), Expect = 3e-04 Identities = 48/228 (21%), Positives = 88/228 (38%), Gaps = 28/228 (12%) Query: 224 LSREEKKES-----LRSSVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRH 278 LS E K+ ++ K + L K L+ RD K+ E Q + L Sbjct: 385 LSSESKRADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHL---- 440 Query: 279 QEFVHMYNAQCDALHPKSAAEIVQEIENIEKTRMRLEASKLNESVMVFTKDQTEKEIDEI 338 Q DA KS + EI +E + + N+ + + + + I+E+ Sbjct: 441 --------NQTDASATKSYENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSENERIEEL 492 Query: 339 HSKYRKKHKSEFQLLVDQARKGYKKIAGMSQKTVTITK---------EDESTEKLSSVCM 389 + +KH+ +L +Q R ++I + Q+ + K E ES+ KL Sbjct: 493 QEQLEQKHRKMNELETEQ-RLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLE 551 Query: 390 GQEDNMTSVTNHFSQSKLDSPEELEPDREEDSSSCIDIQEVLSSSESD 437 + +T V Q K + E+L+PD ++ +++ L + D Sbjct: 552 AHMEKLTEVHEEL-QKKQELIEDLQPDINQNVQKINELEAALQKKDED 598 >gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens] Length = 350 Score = 43.9 bits (102), Expect = 3e-04 Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 4/65 (6%) Query: 25 CGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQCPTCCVTV--TEP--DLKNNRILDE 80 C IC Y A I +C H +C CI + Y +CP C + V T+P +++ +R L + Sbjct: 134 CSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYNIRLDRQLQD 193 Query: 81 LVKSL 85 +V L Sbjct: 194 IVYKL 198 >gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens] Length = 493 Score = 43.9 bits (102), Expect = 3e-04 Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 17 KTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKTQ--CPTCCVTVTEPDLKN 74 ++ + L C +C++ F A+ + +C HN+C C+ + + CP C + DL+ Sbjct: 13 RSFKEELLCAVCYDPFRDAVTL-RCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRT 71 Query: 75 NRILDELVKSL 85 N L+ LV+ L Sbjct: 72 NHTLNNLVEKL 82 >gi|223890259 midline 2 isoform 2 [Homo sapiens] Length = 705 Score = 43.5 bits (101), Expect = 4e-04 Identities = 68/336 (20%), Positives = 130/336 (38%), Gaps = 78/336 (23%) Query: 16 MKTIDDLLRCGICFEYFNIAMIIPQCSHNYCSLCIRKFLSYKT------------QCPTC 63 M+T++ L C IC E F +++P C+H+ C C + L QCPTC Sbjct: 21 METLESELTCPICLELFEDPLLLP-CAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTC 79 Query: 64 CVTVTEPDLKNNRILDELVKSLNFARNHLLQFALESPAKSPASSSSKNLAVKVYTPVASR 123 ++ N+R LD L +++ +N + +F + + S +S S++ + Y P + Sbjct: 80 RYVIS----LNHRGLDGLKRNVTL-QNIIDRF--QKASVSGPNSPSESRRERTYRPTTAM 132 Query: 124 QSLKQGSRLMDNFLIREMSGSTSELLIKENKSKFSPQKEASPAAKTKETRSVEEIAPDPS 183 S + + + P ++A T E + Sbjct: 133 SSERIACQFCEQ----------------------DPPRDAVKTCITCEVSYCDRCLRATH 170 Query: 184 EAKRP-------EPPSTSTLKQVTKVDCPVCGVNIPESHINKHLDS-CLSREEKKESLRS 235 K+P EP + L+ +T +D H N+ ++ C+S ++ +L Sbjct: 171 PNKKPFTSHRLVEPVPDTHLRGITCLD-----------HENEKVNMYCVSDDQLICALCK 219 Query: 236 SVHKRKPLPKTVYNLLSDRDLKKKLKEHGLSIQGNKQQLIKRHQEFVHMYNAQCD----- 290 V + + + + S D +KLK+ +++ N L+KR+ E + Sbjct: 220 LVGRHRD-----HQVASLNDRFEKLKQ---TLEMNLTNLVKRNSELENQMAKLIQICQQV 271 Query: 291 ----ALHPKSAAEIVQEIENIEKTRMRLEASKLNES 322 A+H E E+ I + R ++ A K+ E+ Sbjct: 272 EVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKET 307 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.125 0.350 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,842,422 Number of Sequences: 37866 Number of extensions: 865707 Number of successful extensions: 5012 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 95 Number of HSP's successfully gapped in prelim test: 461 Number of HSP's that attempted gapping in prelim test: 4350 Number of HSP's gapped (non-prelim): 1050 length of query: 495 length of database: 18,247,518 effective HSP length: 106 effective length of query: 389 effective length of database: 14,233,722 effective search space: 5536917858 effective search space used: 5536917858 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.