Search of human proteins with 145309322

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens]
         (566 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens]       1161   0.0  
gi|4504713 insulinoma-associated 1 [Homo sapiens]                     311   1e-84
gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo...    74   5e-13
gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo...    74   5e-13
gi|110681708 zinc finger protein 579 [Homo sapiens]                    67   6e-11
gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]             62   1e-09
gi|37622341 zinc finger protein 42 isoform 2 [Homo sapiens]            60   7e-09
gi|37622345 zinc finger protein 42 isoform 1 [Homo sapiens]            60   7e-09
gi|40807465 zinc finger protein 341 [Homo sapiens]                     59   2e-08
gi|187761351 growth factor independent 1 [Homo sapiens]                58   2e-08
gi|187761349 growth factor independent 1 [Homo sapiens]                58   2e-08
gi|71037377 growth factor independent 1 [Homo sapiens]                 58   2e-08
gi|154146199 sal-like 3 [Homo sapiens]                                 58   2e-08
gi|38348236 zinc finger protein 497 [Homo sapiens]                     58   3e-08
gi|212286156 zinc finger and BTB domain containing 42 [Homo sapi...    57   3e-08
gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]          57   3e-08
gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]          57   3e-08
gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]          57   3e-08
gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]          57   3e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    56   8e-08
gi|116875834 zinc finger protein 74 [Homo sapiens]                     56   8e-08
gi|146198654 zinc finger protein 768 [Homo sapiens]                    56   8e-08
gi|24432013 zinc finger protein 668 [Homo sapiens]                     56   8e-08
gi|116256460 zinc finger protein 775 [Homo sapiens]                    55   1e-07
gi|215820619 zinc finger protein 646 [Homo sapiens]                    55   2e-07
gi|154744870 zinc finger protein 574 [Homo sapiens]                    54   3e-07
gi|152963637 zinc finger protein 787 [Homo sapiens]                    54   4e-07
gi|14249488 zinc finger and SCAN domain containing 10 [Homo sapi...    54   5e-07
gi|153945765 mitogen-activated protein kinase kinase kinase 1 [H...    53   9e-07
gi|45331217 zinc finger protein 526 [Homo sapiens]                     53   9e-07

>gi|145309322 insulinoma-associated protein IA-6 [Homo sapiens]
          Length = 566

 Score = 1161 bits (3004), Expect = 0.0
 Identities = 566/566 (100%), Positives = 566/566 (100%)

Query: 1   MPRGFLVKRTKRTGGLYRVRLAERVFPLLGPQGAPPFLEEAPSASLPGAERATPPTREEP 60
           MPRGFLVKRTKRTGGLYRVRLAERVFPLLGPQGAPPFLEEAPSASLPGAERATPPTREEP
Sbjct: 1   MPRGFLVKRTKRTGGLYRVRLAERVFPLLGPQGAPPFLEEAPSASLPGAERATPPTREEP 60

Query: 61  GKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAEL 120
           GKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAEL
Sbjct: 61  GKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAEL 120

Query: 121 RRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPD 180
           RRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPD
Sbjct: 121 RRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPD 180

Query: 181 PAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLK 240
           PAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLK
Sbjct: 181 PAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLK 240

Query: 241 IKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVF 300
           IKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVF
Sbjct: 241 IKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVF 300

Query: 301 SCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIE 360
           SCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIE
Sbjct: 301 SCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIE 360

Query: 361 RTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGG 420
           RTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGG
Sbjct: 361 RTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGG 420

Query: 421 RGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFP 480
           RGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFP
Sbjct: 421 RGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFP 480

Query: 481 TADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGL 540
           TADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGL
Sbjct: 481 TADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGL 540

Query: 541 TRHINKCHPSESRQVLLLQMPLRPGC 566
           TRHINKCHPSESRQVLLLQMPLRPGC
Sbjct: 541 TRHINKCHPSESRQVLLLQMPLRPGC 566


>gi|4504713 insulinoma-associated 1 [Homo sapiens]
          Length = 510

 Score =  311 bits (796), Expect = 1e-84
 Identities = 244/621 (39%), Positives = 283/621 (45%), Gaps = 166/621 (26%)

Query: 1   MPRGFLVKRTKRTGGL-YRVRLAE---RVFPLLGPQGAPPFLEEAPSASLPGAERATPPT 56
           MPRGFLVKR+K++  + YRVR  E   R   LL P       E    + +PG     PP 
Sbjct: 1   MPRGFLVKRSKKSTPVSYRVRGGEDGDRAL-LLSPSCGGARAEPPAPSPVPGP-LPPPPP 58

Query: 57  REEPGKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPA 116
            E     L A  A       C A G  P   G   A +  G  E   P+P  SP+  +P 
Sbjct: 59  AERAHAALAAALA-------C-APGPQPPPQGPRAAHF--GNPEAAHPAPLYSPT--RPV 106

Query: 117 GAELRR-AFLERC--LSSPVSAESFP-----------GGAAAVAAFSCSVAPAAAPTPGE 162
             E  +  + ER   L SPVSAESFP           GGA+                P E
Sbjct: 107 SREHEKHKYFERSFNLGSPVSAESFPTPAALLGGGGGGGASGAGGGGTCGGDPLLFAPAE 166

Query: 163 QFLLPLRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKAPTD--CASGPAAA----GI 216
             +    +   E A  P P P       L  AA     GK P     A  PA A    G 
Sbjct: 167 LKMGTAFSAGAEAARGPGPGP------PLPPAAALRPPGKRPPPPTAAEPPAKAVKAPGA 220

Query: 217 KKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPF 276
           KKPKA+RKL F DEVTTSPVLGLKIKE    AP    GG+  PLGEFICQLCKE+YADPF
Sbjct: 221 KKPKAIRKLHFEDEVTTSPVLGLKIKEGPVEAPRGRAGGAARPLGEFICQLCKEEYADPF 280

Query: 277 ALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSS 336
           ALAQH+CSRIVRVEYRCPEC KVFSCPANLASHRRWHKPRPA A A              
Sbjct: 281 ALAQHKCSRIVRVEYRCPECAKVFSCPANLASHRRWHKPRPAPAAARAP----------- 329

Query: 337 SSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPP 396
                                  E  A    +AR++ G     D+              P
Sbjct: 330 -----------------------EPEAAARAEAREAPGGGSDRDT--------------P 352

Query: 397 LPQGPYTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHE------- 449
            P G          V   GS  G     ++ C +C KKFRRQAYLRKHL  H        
Sbjct: 353 SPGG----------VSESGSEDG-----LYECHHCAKKFRRQAYLRKHLLAHHQALQAKG 397

Query: 450 ------AGSARALAPG---------FGSERGAPL--------AFACPLCGAHFPTADIRE 486
                 A    AL PG          G   GA +           CP+CG  F +   +E
Sbjct: 398 APLAPPAEDLLALYPGPDEKAPQEAAGDGEGAGVLGLSASAECHLCPVCGESFASKGAQE 457

Query: 487 KH-RLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHIN 545
           +H RL HA                             Q+F CK+CP+TF+SSPGLTRHIN
Sbjct: 458 RHLRLLHAA----------------------------QVFPCKYCPATFYSSPGLTRHIN 489

Query: 546 KCHPSESRQVLLLQMPLRPGC 566
           KCHPSE+RQV+LLQ+P+RP C
Sbjct: 490 KCHPSENRQVILLQVPVRPAC 510


>gi|239757409 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 139/599 (23%), Positives = 192/599 (32%), Gaps = 144/599 (24%)

Query: 42  PSASLPGAERATPPTREE-----PGKGLTAEAARE------QSGSPCRAAGVSPGTGGRE 90
           P   LP A  A PP   +     P  G+   +  +      + G P    GV+PG G   
Sbjct: 122 PDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPGLGAPA 181

Query: 91  GAEWRAGGREGPGPSPSPSPSPAKPAGAE-----------LRRA--FLERCLSSPVSAES 137
           GA         PGP P+PS +P  P  A             RR    +ER     V  +S
Sbjct: 182 GA---------PGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYLMERRFPCGVCQKS 232

Query: 138 FPGGAAAVA---------AFSCSVA---------------------PAAA--PTPGEQFL 165
           F   +  V           + C V                      PAA   P PG    
Sbjct: 233 FKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPPQPGPHLP 292

Query: 166 -LPLRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKA-PTDCASGPAAAG-------- 215
            L L AP    A    P+ +S+   +   A      G A P      P A G        
Sbjct: 293 PLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFAC 352

Query: 216 ------IKKPKAMRK---LSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQ 266
                  KKP  + +   +   ++  +  V        E  +  R +      L    C 
Sbjct: 353 PLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRE--SLKRHVKTHSADLLRLPCG 410

Query: 267 LCKEQYADPFALAQHRCSRI------VRVEYRCPECDKVFSCPANLASHRRWHKPRPAAA 320
           +C + + D   L +H+ +         R  Y C  C K +S P +L  H+  H P  AAA
Sbjct: 411 ICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAAA 470

Query: 321 NAATVSSADGK-------------PPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHP 367
            A    +A                PP   ++ S  + A A+ +  G     +      HP
Sbjct: 471 EAPKDGAASAPQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVYGAVPVPL---LGAHP 527

Query: 368 QARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIFV 427
                +G       A   G  V   P      G    G  GRR  +        G +   
Sbjct: 528 LLLGGAGTS----GAGGSGASV---PGKTFCCGICGRG-FGRRETLKRHERIHTGEKPHQ 579

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREK 487
           CP C K+FR   +L KH   H               R  P  + C LCG  F       +
Sbjct: 580 CPVCGKRFRESFHLSKHHVVH--------------TRERP--YKCELCGKVFGYPQSLTR 623

Query: 488 HRLWHAVREELLLPALAGAP-----PETSGP------SGPSDGSAQQIFSC-KHCPSTF 534
           HR  H ++    L   AG P     P   GP      +GP+DG +     C +H P  F
Sbjct: 624 HRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLF 682



 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 100/457 (21%), Positives = 151/457 (33%), Gaps = 74/457 (16%)

Query: 102 PGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPTPG 161
           PGP P P P P  P      ++  +     P S+ S    +++ ++ S S + +++    
Sbjct: 62  PGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKK 121

Query: 162 EQFLLPLRAPFPEPALQ----PDPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAA-GI 216
               LP     P P L     P P      L   +   G  +RG      ASGP    G+
Sbjct: 122 PDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGP----ASGPGVTPGL 177

Query: 217 KKPK-AMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGE--FICQLCKEQYA 273
             P  A   L    +    P         +P    +G       L E  F C +C++ + 
Sbjct: 178 GAPAGAPGPLPAPSQTPPGPPAAAAC---DPTKDDKGYFRRLKYLMERRFPCGVCQKSFK 234

Query: 274 DPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPP 333
               L QH         Y C  C + ++  ++L  HRR HK  P AA           PP
Sbjct: 235 QSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPP-QPGPHLPP 293

Query: 334 SSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHP 393
               + +  +   A+             T    P A   + A     SA   G+ V    
Sbjct: 294 LGLPAPAASAATAAA-----------PSTVSSGPPATPVAPAPSADGSAAPAGVGV---- 338

Query: 394 EPPLP---QGPYTEGVLGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLS 446
            PP      GP+   +  +    P      +    G + F C  C K F R+  L++H+ 
Sbjct: 339 PPPATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVK 398

Query: 447 THEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGA 506
           TH A   R                 C +CG  F  A    KH+  HA             
Sbjct: 399 THSADLLR---------------LPCGICGKAFRDASYLLKHQAAHA------------- 430

Query: 507 PPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRH 543
                   G   G  + ++ C  C  ++ +   L RH
Sbjct: 431 --------GAGAGGPRPVYPCDLCGKSYSAPQSLLRH 459



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 76/314 (24%), Positives = 114/314 (36%), Gaps = 47/314 (14%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP--AAANA 322
           C +C +++ + F L++H         Y+C  C KVF  P +L  HR+ H+ +   A A A
Sbjct: 580 CPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRLQLPCALAGA 639

Query: 323 ATVSSADGKP----PSSSSSSSRDSGAIASFLAEGKEN--------SRIERTADQHPQAR 370
           A + S  G P    P +S +S+  +  ++   ++  E+        S  E    + P   
Sbjct: 640 AGLPSTQGTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGC 699

Query: 371 DSSGAD-QHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIFVCP 429
           D+ G      ++     L     PE  LP  P      G   P  GS SG   + +    
Sbjct: 700 DACGKTFGFIENLMWHKLVHQAAPERLLPPAP------GGLQPPDGS-SGTDAASVLDNG 752

Query: 430 YCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHR 489
              +     A L       +AG A     G G+  G P  F+C  CG  F        H+
Sbjct: 753 LAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSG-PERFSCATCGQSFKHFLGLVTHK 811

Query: 490 LWHAVREELLLPALAGAPPETSGPSGPSDGSAQQI------------FSCKHCPSTFFSS 537
             H VR  L             G  G S   A  +            F C  C   F+ +
Sbjct: 812 YVHLVRRTL-----------GCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEA 860

Query: 538 PGLTRHINKCHPSE 551
             L RH  +CH  +
Sbjct: 861 ALLMRH-QRCHTEQ 873



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 84/342 (24%), Positives = 114/342 (33%), Gaps = 40/342 (11%)

Query: 238 GLKIKEEEPGAPSRGLGGSR---TPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCP 294
           GL   +  PGA   G  G+    T    + C  C E + D F +  H+   +    Y C 
Sbjct: 641 GLPSTQGTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCD 700

Query: 295 ECDKVFSCPANLASHRRWHKPRPAAANAATVSSADG--KPPSSSSSSSRDS--------- 343
            C K F    NL     WHK    AA    +  A G  +PP  SS +   S         
Sbjct: 701 ACGKTFGFIENL----MWHKLVHQAAPERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGE 756

Query: 344 -GAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQG----LQVLTHPEPPLP 398
            GA  + LA           A        SSG ++   +   Q     L ++TH    L 
Sbjct: 757 VGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLV 816

Query: 399 QGPYTEGVLGR----RVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTH-EAGSA 453
           +     G+ G+       +       R    F CP C K+F   A L +H   H E    
Sbjct: 817 RRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPY 876

Query: 454 RALAPGFGSERGAPL-----------AFACPLCGAHFPTADIREKHRLWHAVREELLLPA 502
           R    G G  R   L           AF C +C   F  +    +HR  HAV       A
Sbjct: 877 RCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSA 936

Query: 503 LAGAPPETSG-PSGPSDGSAQQIFSCKHCPSTFFSSPGLTRH 543
                   S           ++ + C+HC   FF    + RH
Sbjct: 937 CGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRH 978



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 31/117 (26%), Positives = 49/117 (41%), Gaps = 5/117 (4%)

Query: 201 GKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPL 260
           G  P D +SG  AA +       ++  A     + + G+   E+  GA   G GG  +  
Sbjct: 733 GLQPPDGSSGTDAASVLDNGLAGEVGAA----VAALAGVSGGEDAGGAAVAGAGGGASSG 788

Query: 261 GE-FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPR 316
            E F C  C + +     L  H+   +VR    C  C + F+   +L  HRR H+ +
Sbjct: 789 PERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQK 845



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 16/65 (24%)

Query: 428  CPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREK 487
            CP C K F+   Y RKHL+ H+ G                  F C  CG  F      +K
Sbjct: 991  CPACLKAFKDPGYFRKHLAAHQGGR----------------PFRCSSCGEGFANTYGLKK 1034

Query: 488  HRLWH 492
            HRL H
Sbjct: 1035 HRLAH 1039



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 19/73 (26%), Positives = 27/73 (36%)

Query: 259  PLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPA 318
            P  E  C  C + + DP    +H  +      +RC  C + F+    L  HR  HK    
Sbjct: 985  PRAELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENL 1044

Query: 319  AANAATVSSADGK 331
                A   +  GK
Sbjct: 1045 GGPGAGAGTLAGK 1057



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 14/51 (27%), Positives = 24/51 (47%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKP 315
           C  C + +     L +H+   +    YRC  C K F   +++  H+R H+P
Sbjct: 934 CSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEP 984



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 44/175 (25%), Positives = 58/175 (33%), Gaps = 22/175 (12%)

Query: 389  VLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKH 444
            ++ H      Q PY  GV GR           R    G   F C  C K+F + + L +H
Sbjct: 863  LMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEH 922

Query: 445  LSTHE-AGSARALAPGFGSERGAPL-----------AFACPLCG-AHFPTADIREKHRLW 491
               H  A   R  A G      + L           A+ C  CG   F  + +    R  
Sbjct: 923  RRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAH 982

Query: 492  HAVREELLLPALAGA---PPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRH 543
               R EL  PA   A   P           G   + F C  C   F ++ GL +H
Sbjct: 983  EPPRAELRCPACLKAFKDPGYFRKHLAAHQGG--RPFRCSSCGEGFANTYGLKKH 1035



 Score = 29.6 bits (65), Expect = 7.7
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 257  RTPLGE--FICQLCKEQYADPFALAQH-RCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
            R  LGE  + C+ C + +    ++ +H R     R E RCP C K F  P     H   H
Sbjct: 952  RLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEPPRAELRCPACLKAFKDPGYFRKHLAAH 1011

Query: 314  K 314
            +
Sbjct: 1012 Q 1012


>gi|239746371 PREDICTED: similar to zinc finger protein 208 [Homo
           sapiens]
          Length = 1059

 Score = 73.6 bits (179), Expect = 5e-13
 Identities = 139/599 (23%), Positives = 192/599 (32%), Gaps = 144/599 (24%)

Query: 42  PSASLPGAERATPPTREE-----PGKGLTAEAARE------QSGSPCRAAGVSPGTGGRE 90
           P   LP A  A PP   +     P  G+   +  +      + G P    GV+PG G   
Sbjct: 122 PDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGPASGPGVTPGLGAPA 181

Query: 91  GAEWRAGGREGPGPSPSPSPSPAKPAGAE-----------LRRA--FLERCLSSPVSAES 137
           GA         PGP P+PS +P  P  A             RR    +ER     V  +S
Sbjct: 182 GA---------PGPLPAPSQTPPGPPAAAACDPTKDDKGYFRRLKYLMERRFPCGVCQKS 232

Query: 138 FPGGAAAVA---------AFSCSVA---------------------PAAA--PTPGEQFL 165
           F   +  V           + C V                      PAA   P PG    
Sbjct: 233 FKQSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPPQPGPHLP 292

Query: 166 -LPLRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKA-PTDCASGPAAAG-------- 215
            L L AP    A    P+ +S+   +   A      G A P      P A G        
Sbjct: 293 PLGLPAPAASAATAAAPSTVSSGPPATPVAPAPSADGSAAPAGVGVPPPATGGGDGPFAC 352

Query: 216 ------IKKPKAMRK---LSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQ 266
                  KKP  + +   +   ++  +  V        E  +  R +      L    C 
Sbjct: 353 PLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRE--SLKRHVKTHSADLLRLPCG 410

Query: 267 LCKEQYADPFALAQHRCSRI------VRVEYRCPECDKVFSCPANLASHRRWHKPRPAAA 320
           +C + + D   L +H+ +         R  Y C  C K +S P +L  H+  H P  AAA
Sbjct: 411 ICGKAFRDASYLLKHQAAHAGAGAGGPRPVYPCDLCGKSYSAPQSLLRHKAAHAPPAAAA 470

Query: 321 NAATVSSADGK-------------PPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHP 367
            A    +A                PP   ++ S  + A A+ +  G     +      HP
Sbjct: 471 EAPKDGAASAPQPPPTFPPGPYLLPPDPPTTDSEKAAAAAAAVVYGAVPVPL---LGAHP 527

Query: 368 QARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIFV 427
                +G       A   G  V   P      G    G  GRR  +        G +   
Sbjct: 528 LLLGGAGTS----GAGGSGASV---PGKTFCCGICGRG-FGRRETLKRHERIHTGEKPHQ 579

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREK 487
           CP C K+FR   +L KH   H               R  P  + C LCG  F       +
Sbjct: 580 CPVCGKRFRESFHLSKHHVVH--------------TRERP--YKCELCGKVFGYPQSLTR 623

Query: 488 HRLWHAVREELLLPALAGAP-----PETSGP------SGPSDGSAQQIFSC-KHCPSTF 534
           HR  H ++    L   AG P     P   GP      +GP+DG +     C +H P  F
Sbjct: 624 HRQVHRLQLPCALAGAAGLPSTQGTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLF 682



 Score = 69.7 bits (169), Expect = 7e-12
 Identities = 100/457 (21%), Positives = 151/457 (33%), Gaps = 74/457 (16%)

Query: 102 PGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPTPG 161
           PGP P P P P  P      ++  +     P S+ S    +++ ++ S S + +++    
Sbjct: 62  PGPPPQPPPQPPPPQYDYPPQSTFKPKAEVPSSSSSSSSSSSSSSSSSSSSSSSSSQAKK 121

Query: 162 EQFLLPLRAPFPEPALQ----PDPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAA-GI 216
               LP     P P L     P P      L   +   G  +RG      ASGP    G+
Sbjct: 122 PDPPLPPAFGAPPPPLFDAAFPTPQWGIVDLSGHQHLFGNLKRGGP----ASGPGVTPGL 177

Query: 217 KKPK-AMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGE--FICQLCKEQYA 273
             P  A   L    +    P         +P    +G       L E  F C +C++ + 
Sbjct: 178 GAPAGAPGPLPAPSQTPPGPPAAAAC---DPTKDDKGYFRRLKYLMERRFPCGVCQKSFK 234

Query: 274 DPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPP 333
               L QH         Y C  C + ++  ++L  HRR HK  P AA           PP
Sbjct: 235 QSSHLVQHMLVHSGERPYECGVCGRTYNHVSSLIRHRRCHKDVPPAAGGPP-QPGPHLPP 293

Query: 334 SSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHP 393
               + +  +   A+             T    P A   + A     SA   G+ V    
Sbjct: 294 LGLPAPAASAATAAA-----------PSTVSSGPPATPVAPAPSADGSAAPAGVGV---- 338

Query: 394 EPPLP---QGPYTEGVLGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLS 446
            PP      GP+   +  +    P      +    G + F C  C K F R+  L++H+ 
Sbjct: 339 PPPATGGGDGPFACPLCWKVFKKPSHLHQHQIIHTGEKPFSCSVCSKSFNRRESLKRHVK 398

Query: 447 THEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGA 506
           TH A   R                 C +CG  F  A    KH+  HA             
Sbjct: 399 THSADLLR---------------LPCGICGKAFRDASYLLKHQAAHA------------- 430

Query: 507 PPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRH 543
                   G   G  + ++ C  C  ++ +   L RH
Sbjct: 431 --------GAGAGGPRPVYPCDLCGKSYSAPQSLLRH 459



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 76/314 (24%), Positives = 114/314 (36%), Gaps = 47/314 (14%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP--AAANA 322
           C +C +++ + F L++H         Y+C  C KVF  P +L  HR+ H+ +   A A A
Sbjct: 580 CPVCGKRFRESFHLSKHHVVHTRERPYKCELCGKVFGYPQSLTRHRQVHRLQLPCALAGA 639

Query: 323 ATVSSADGKP----PSSSSSSSRDSGAIASFLAEGKEN--------SRIERTADQHPQAR 370
           A + S  G P    P +S +S+  +  ++   ++  E+        S  E    + P   
Sbjct: 640 AGLPSTQGTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGC 699

Query: 371 DSSGAD-QHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIFVCP 429
           D+ G      ++     L     PE  LP  P      G   P  GS SG   + +    
Sbjct: 700 DACGKTFGFIENLMWHKLVHQAAPERLLPPAP------GGLQPPDGS-SGTDAASVLDNG 752

Query: 430 YCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHR 489
              +     A L       +AG A     G G+  G P  F+C  CG  F        H+
Sbjct: 753 LAGEVGAAVAALAGVSGGEDAGGAAVAGAGGGASSG-PERFSCATCGQSFKHFLGLVTHK 811

Query: 490 LWHAVREELLLPALAGAPPETSGPSGPSDGSAQQI------------FSCKHCPSTFFSS 537
             H VR  L             G  G S   A  +            F C  C   F+ +
Sbjct: 812 YVHLVRRTL-----------GCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEA 860

Query: 538 PGLTRHINKCHPSE 551
             L RH  +CH  +
Sbjct: 861 ALLMRH-QRCHTEQ 873



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 84/342 (24%), Positives = 114/342 (33%), Gaps = 40/342 (11%)

Query: 238 GLKIKEEEPGAPSRGLGGSR---TPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCP 294
           GL   +  PGA   G  G+    T    + C  C E + D F +  H+   +    Y C 
Sbjct: 641 GLPSTQGTPGACGPGASGTSAGPTDGLSYACSDCGEHFPDLFHVMSHKEVHMAEKPYGCD 700

Query: 295 ECDKVFSCPANLASHRRWHKPRPAAANAATVSSADG--KPPSSSSSSSRDS--------- 343
            C K F    NL     WHK    AA    +  A G  +PP  SS +   S         
Sbjct: 701 ACGKTFGFIENL----MWHKLVHQAAPERLLPPAPGGLQPPDGSSGTDAASVLDNGLAGE 756

Query: 344 -GAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQG----LQVLTHPEPPLP 398
            GA  + LA           A        SSG ++   +   Q     L ++TH    L 
Sbjct: 757 VGAAVAALAGVSGGEDAGGAAVAGAGGGASSGPERFSCATCGQSFKHFLGLVTHKYVHLV 816

Query: 399 QGPYTEGVLGR----RVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTH-EAGSA 453
           +     G+ G+       +       R    F CP C K+F   A L +H   H E    
Sbjct: 817 RRTLGCGLCGQSFAGAYDLLLHRRSHRQKRGFRCPVCGKRFWEAALLMRHQRCHTEQRPY 876

Query: 454 RALAPGFGSERGAPL-----------AFACPLCGAHFPTADIREKHRLWHAVREELLLPA 502
           R    G G  R   L           AF C +C   F  +    +HR  HAV       A
Sbjct: 877 RCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEHRRLHAVARPQRCSA 936

Query: 503 LAGAPPETSG-PSGPSDGSAQQIFSCKHCPSTFFSSPGLTRH 543
                   S           ++ + C+HC   FF    + RH
Sbjct: 937 CGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRH 978



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 31/117 (26%), Positives = 49/117 (41%), Gaps = 5/117 (4%)

Query: 201 GKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPL 260
           G  P D +SG  AA +       ++  A     + + G+   E+  GA   G GG  +  
Sbjct: 733 GLQPPDGSSGTDAASVLDNGLAGEVGAA----VAALAGVSGGEDAGGAAVAGAGGGASSG 788

Query: 261 GE-FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPR 316
            E F C  C + +     L  H+   +VR    C  C + F+   +L  HRR H+ +
Sbjct: 789 PERFSCATCGQSFKHFLGLVTHKYVHLVRRTLGCGLCGQSFAGAYDLLLHRRSHRQK 845



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 16/65 (24%)

Query: 428  CPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREK 487
            CP C K F+   Y RKHL+ H+ G                  F C  CG  F      +K
Sbjct: 991  CPACLKAFKDPGYFRKHLAAHQGGR----------------PFRCSSCGEGFANTYGLKK 1034

Query: 488  HRLWH 492
            HRL H
Sbjct: 1035 HRLAH 1039



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 19/73 (26%), Positives = 27/73 (36%)

Query: 259  PLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPA 318
            P  E  C  C + + DP    +H  +      +RC  C + F+    L  HR  HK    
Sbjct: 985  PRPELRCPACLKAFKDPGYFRKHLAAHQGGRPFRCSSCGEGFANTYGLKKHRLAHKAENL 1044

Query: 319  AANAATVSSADGK 331
                A   +  GK
Sbjct: 1045 GGPGAGAGTLAGK 1057



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 14/51 (27%), Positives = 24/51 (47%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKP 315
           C  C + +     L +H+   +    YRC  C K F   +++  H+R H+P
Sbjct: 934 CSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAHEP 984



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 44/175 (25%), Positives = 58/175 (33%), Gaps = 22/175 (12%)

Query: 389  VLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKH 444
            ++ H      Q PY  GV GR           R    G   F C  C K+F + + L +H
Sbjct: 863  LMRHQRCHTEQRPYRCGVCGRGFLRSWYLRQHRVVHTGERAFKCGVCAKRFAQSSSLAEH 922

Query: 445  LSTHE-AGSARALAPGFGSERGAPL-----------AFACPLCG-AHFPTADIREKHRLW 491
               H  A   R  A G      + L           A+ C  CG   F  + +    R  
Sbjct: 923  RRLHAVARPQRCSACGKTFRYRSNLLEHQRLHLGERAYRCEHCGKGFFYLSSVLRHQRAH 982

Query: 492  HAVREELLLPALAGA---PPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRH 543
               R EL  PA   A   P           G   + F C  C   F ++ GL +H
Sbjct: 983  EPPRPELRCPACLKAFKDPGYFRKHLAAHQGG--RPFRCSSCGEGFANTYGLKKH 1035


>gi|110681708 zinc finger protein 579 [Homo sapiens]
          Length = 562

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 67/280 (23%), Positives = 94/280 (33%), Gaps = 39/280 (13%)

Query: 246 PGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPAN 305
           P     G GG         C +C + +A P++L++HR        + CP+C   F   + 
Sbjct: 253 PEGEQEGEGGPPPRPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASY 312

Query: 306 LASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQ 365
           L  HRR H P    A        D K   + +S+    G   +      E    +   D 
Sbjct: 313 LRQHRRVHGPLSLLAPLPAAGKKDDKASGARNSAKGPEGGEGAECGGASEGGEGQNGGDA 372

Query: 366 HPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEI 425
            P AR  +G  +       +G +   H    L Q   T                  G+  
Sbjct: 373 AP-ARPPAGEPRFWCPECGKGFRRRAH----LRQHGVTHS----------------GARP 411

Query: 426 FVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIR 485
           F C  C ++F+R A L +H   H                G P    CP C   F  A   
Sbjct: 412 FQCVRCQREFKRLADLARHAQVH---------------AGGPAPHPCPRCPRRFSRAYSL 456

Query: 486 EKHRLWHAVREE--LLLPALAGAPPETSGPSGPSDGSAQQ 523
            +H+  H    E    L AL    P TS P  P    A+Q
Sbjct: 457 LRHQRCHRAELERAAALQALQAQAP-TSPPPPPPPLKAEQ 495



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 65/276 (23%), Positives = 95/276 (34%), Gaps = 31/276 (11%)

Query: 251 RGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHR 310
           RG GG+  P     C  C   +  P+ L++HR S      + CP C K F  PA+L+ H 
Sbjct: 32  RGRGGAGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHL 91

Query: 311 RWHKPRPAAANAATVSSADGKPPSSSSSSSRDSG-----AIASFLAEGKENSRIERTADQ 365
           R H P+P    AA   +           +   +G     AI     E  E S   +    
Sbjct: 92  RGHGPQPPLRCAACPRTFPEPAQLRRHLAQEHAGGEVELAIERVAKETAEPSWGPQDEGS 151

Query: 366 HPQARDSSGADQH------PDSAPRQGLQVLTHP----EPPLPQGPYTE-GVLGRRVPVP 414
            P    ++GA +       P++ P      L  P    EP   +    E G    R  + 
Sbjct: 152 EPPTTAAAGATEEEAVAAWPETWPAGEPSTLAAPTSAAEPRESESEEAEAGAAELRAEL- 210

Query: 415 GSTSGGRGSE---------IFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERG 465
            + + GR  E           +C  C + F  +  L+ H      G       G G    
Sbjct: 211 -ALAAGRQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQE----GEGGPPP 265

Query: 466 APLAFACPLCGAHFPTADIREKHRLWHAVREELLLP 501
            P    C +C   F       +HRL H+     + P
Sbjct: 266 RPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCP 301



 Score = 36.2 bits (82), Expect = 0.082
 Identities = 39/131 (29%), Positives = 47/131 (35%), Gaps = 24/131 (18%)

Query: 398 PQGPYTEGVLGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSA 453
           P+ P      GR    P   S  R    G     CP C K FRR A+L +HL  H     
Sbjct: 40  PRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGH----- 94

Query: 454 RALAPGFGSERGAPLAFACPLCGAHFP-TADIREKHRLWHAVREELLLPALAGAPPETSG 512
                      G      C  C   FP  A +R      HA  E  L  A+     ET+ 
Sbjct: 95  -----------GPQPPLRCAACPRTFPEPAQLRRHLAQEHAGGEVEL--AIERVAKETAE 141

Query: 513 PS-GPSDGSAQ 522
           PS GP D  ++
Sbjct: 142 PSWGPQDEGSE 152



 Score = 32.7 bits (73), Expect = 0.91
 Identities = 32/103 (31%), Positives = 37/103 (35%), Gaps = 5/103 (4%)

Query: 451 GSARALAPGFGSERG---APLA-FACPLCGAHFPTADIREKHRLWHAVREELLLPALAGA 506
           G  R    G G  RG   AP A   CP CG  F       +HRL H+       P    A
Sbjct: 21  GRGRGRGRGRGRGRGGAGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKA 80

Query: 507 PPETSGPSGPSDG-SAQQIFSCKHCPSTFFSSPGLTRHINKCH 548
               +  S    G   Q    C  CP TF     L RH+ + H
Sbjct: 81  FRRPAHLSRHLRGHGPQPPLRCAACPRTFPEPAQLRRHLAQEH 123


>gi|170932550 FLT3-interacting zinc finger 1 [Homo sapiens]
          Length = 496

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 82/369 (22%), Positives = 117/369 (31%), Gaps = 70/369 (18%)

Query: 190 SLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKE--EEPG 247
           SL R    + RG  P+    GP    +  P      S    V    V G       E P 
Sbjct: 121 SLGRHLKRQHRGVLPSPLQPGPGLPALSAP-----CSVCCNVGPCSVCGGSGAGGGEGPE 175

Query: 248 APSRGLGG---------SRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDK 298
               GLG          +   L  F C  C  ++     LA H  +      ++CP C++
Sbjct: 176 GAGAGLGSWGLAEAAAAAAASLPPFACGACARRFDHGRELAAHWAAHTDVKPFKCPRCER 235

Query: 299 VFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSR 358
            F+ PA L  H+  H  +             G PP+ + ++   +G   +      E   
Sbjct: 236 DFNAPALLERHKLTHDLQ-----------GPGAPPAQAWAAGPGAGPETAGEGTAAEAGD 284

Query: 359 IERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTS 418
               +D+      + G        P+ G          LP+G       G   P P + +
Sbjct: 285 APLASDRRLLLGPAGGG------VPKLG--------GLLPEG-------GGEAPAPAAAA 323

Query: 419 GGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAH 478
                 ++ C  C   F   A L  HL  H                  P  + C  CGA 
Sbjct: 324 EPSEDTLYQCD-CGTFFASAAALASHLEAHSG----------------PATYGCGHCGAL 366

Query: 479 FPTADIREKHRL---WHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFF 535
           +      E+HR         EE    A    P     PSG   G  ++IF C  C   F 
Sbjct: 367 YAALAALEEHRRVSHGEGGGEEAATAAREREPASGEPPSG--SGRGKKIFGCSECEKLFR 424

Query: 536 SSPGLTRHI 544
           S   L RH+
Sbjct: 425 SPRDLERHV 433



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 112/454 (24%), Positives = 146/454 (32%), Gaps = 104/454 (22%)

Query: 51  RATPPTREEPGKGLTAEAAREQ---SGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPS 107
           R   P+  +PG GL A +A      +  PC   G S G GG EG E    G    G + +
Sbjct: 131 RGVLPSPLQPGPGLPALSAPCSVCCNVGPCSVCGGS-GAGGGEGPEGAGAGLGSWGLAEA 189

Query: 108 PSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSC--SVAPAAAPTPGEQFL 165
                A  A A L       C      A  F  G    A ++    V P   P     F 
Sbjct: 190 -----AAAAAASLPPFACGAC------ARRFDHGRELAAHWAAHTDVKPFKCPRCERDFN 238

Query: 166 LP--LRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAM- 222
            P  L        LQ   AP + A      AAG    G  P     G AA     P A  
Sbjct: 239 APALLERHKLTHDLQGPGAPPAQAW-----AAGP---GAGPETAGEGTAAEAGDAPLASD 290

Query: 223 RKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHR 282
           R+L         P LG  + E    AP+       +    + C  C   +A   ALA H 
Sbjct: 291 RRLLLGPAGGGVPKLGGLLPEGGGEAPAPAAAAEPSEDTLYQCD-CGTFFASAAALASHL 349

Query: 283 CSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVS----SADGKPPSSSSS 338
            +      Y C  C  +++  A L  HRR          AAT +     A G+PPS S  
Sbjct: 350 EAHSGPATYGCGHCGALYAALAALEEHRRVSHGEGGGEEAATAAREREPASGEPPSGSGR 409

Query: 339 SSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLP 398
             +  G      +E ++  R  R  ++H                      VL H      
Sbjct: 410 GKKIFGC-----SECEKLFRSPRDLERH----------------------VLVH------ 436

Query: 399 QGPYTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAP 458
                                  G + F C  C K FR + YL++H   H          
Sbjct: 437 ----------------------TGEKPFPCLECGKFFRHECYLKRHRLLH---------- 464

Query: 459 GFGSERGAPLAFACPLCGAHFPTADIREKHRLWH 492
             G+ER     F C +CG  F T     +H   H
Sbjct: 465 --GTER----PFPCHICGKGFITLSNLSRHLKLH 492



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 63/293 (21%), Positives = 93/293 (31%), Gaps = 38/293 (12%)

Query: 249 PSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLAS 308
           P+     +  P   F C  C + +     L +H         + CP C K F    NLA+
Sbjct: 9   PAPAPPAAAAPRVPFHCSECGKSFRYRSDLRRHFARHTALKPHACPRCGKGFKHSFNLAN 68

Query: 309 HRRWHK-PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHP 367
           H R H   RP   +A      D                    + E + +SR   +  +H 
Sbjct: 69  HLRSHTGERPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCLVCELRFSSR--SSLGRHL 126

Query: 368 QARDSSGADQHPDSAPRQGLQVLTHPEPPL----------------PQGPYTEGV-LGRR 410
           + R   G    P   P  GL  L+ P                     +GP   G  LG  
Sbjct: 127 K-RQHRGVLPSP-LQPGPGLPALSAPCSVCCNVGPCSVCGGSGAGGGEGPEGAGAGLGSW 184

Query: 411 VPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAF 470
                + +       F C  C ++F     L  H + H                     F
Sbjct: 185 GLAEAAAAAAASLPPFACGACARRFDHGRELAAHWAAHTDVK----------------PF 228

Query: 471 ACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQ 523
            CP C   F    + E+H+L H ++     PA A A    +GP    +G+A +
Sbjct: 229 KCPRCERDFNAPALLERHKLTHDLQGPGAPPAQAWAAGPGAGPETAGEGTAAE 281



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 39/155 (25%), Positives = 53/155 (34%), Gaps = 23/155 (14%)

Query: 412 PVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFA 471
           P P   +       F C  C K FR ++ LR+H + H      AL P            A
Sbjct: 9   PAPAPPAAAAPRVPFHCSECGKSFRYRSDLRRHFARH-----TALKP-----------HA 52

Query: 472 CPLCGAHFPTADIREKHRLWHAVREELLLPAL-AGAPPETSGPSGPSDGSAQQIFSCKHC 530
           CP CG  F  +     H   H         A   G    T         + ++ + C  C
Sbjct: 53  CPRCGKGFKHSFNLANHLRSHTGERPYRCSACPKGFRDSTGLLHHQVVHTGEKPYCCLVC 112

Query: 531 PSTFFSSPGLTRHINKCHPSESRQVLLLQMPLRPG 565
              F S   L RH+ + H        +L  PL+PG
Sbjct: 113 ELRFSSRSSLGRHLKRQHRG------VLPSPLQPG 141


>gi|37622341 zinc finger protein 42 isoform 2 [Homo sapiens]
          Length = 734

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 75/313 (23%), Positives = 106/313 (33%), Gaps = 53/313 (16%)

Query: 246 PGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPAN 305
           PGA      G+  P G F C  C+E +A    L +H+        + C EC + F   + 
Sbjct: 468 PGAKPPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERFGRRSV 527

Query: 306 LASHRRWHK-PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTAD 364
           L  HRR H   RP A   A    +  +  + +      +G      AE  +  R   T  
Sbjct: 528 LLQHRRVHSGERPFA--CAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLT 585

Query: 365 QHPQARDSSGADQHPDSAPR--QGLQVLTHPEPPLPQGPYTEGVLGRR-VPVPGSTSGGR 421
           QH +          P+   R  Q L++  H      + PY  G  G     V   T   R
Sbjct: 586 QHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQR 645

Query: 422 ---GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAH 478
              G   F CP C + FR+ A L +H   H              ER     +ACP CG  
Sbjct: 646 IHTGERPFACPECGQSFRQHANLTQHRRIHT------------GER----PYACPECGKA 689

Query: 479 FPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSP 538
           F       +H   H                             ++ F+C+ C   F  S 
Sbjct: 690 FRQRPTLTQHLRTH---------------------------RREKPFACQDCGRRFHQST 722

Query: 539 GLTRHINKCHPSE 551
            L +H  + H +E
Sbjct: 723 KLIQH-QRVHSAE 734



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 68/306 (22%), Positives = 102/306 (33%), Gaps = 56/306 (18%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANA 322
           F+C  C + +     L +HR        +RC EC + F   +NL  H+R H   P     
Sbjct: 412 FVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAK 471

Query: 323 ATVSSADGKPPSS-SSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDS 381
                   +PP     S  R+S A  + L E     +   T D+      S G  +  + 
Sbjct: 472 PPAPPGAPEPPGPFPCSECRESFARRAVLLE----HQAVHTGDK------SFGCVECGER 521

Query: 382 APRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRR 437
             R+ + +L H      + P+     G+      + +  R    G   F C  C K FR+
Sbjct: 522 FGRRSV-LLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQ 580

Query: 438 QAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREE 497
           +  L +HL  H                     FACP CG  F       +H+  H     
Sbjct: 581 RPTLTQHLRVHTGEK----------------PFACPECGQRFSQRLKLTRHQRTH----- 619

Query: 498 LLLPALAGAPPETSGPSGPSDGSAQQI------------FSCKHCPSTFFSSPGLTRHIN 545
                  G  P   G  G       ++            F+C  C  +F     LT+H  
Sbjct: 620 ------TGEKPYHCGECGLGFTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQH-R 672

Query: 546 KCHPSE 551
           + H  E
Sbjct: 673 RIHTGE 678



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 60/271 (22%), Positives = 93/271 (34%), Gaps = 44/271 (16%)

Query: 292 RCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSS-------SSSRDSG 344
           RC  C KVFS  +NL  H++ H           V S  G+  S SS       + + +  
Sbjct: 357 RCDVCGKVFSQRSNLLRHQKIH-----TGERPFVCSECGRSFSRSSHLLRHQLTHTEERP 411

Query: 345 AIASFLAEG-KENSRIERTADQHPQARDSSGADQHPDSAPRQGL--QVLTHPEPPLPQGP 401
            +     +G   ++R+E     H   +    A+       R  L      H +PP P   
Sbjct: 412 FVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGP--- 468

Query: 402 YTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFG 461
                 G + P P       G   F C  C + F R+A L +H + H             
Sbjct: 469 ------GAKPPAPPGAPEPPGP--FPCSECRESFARRAVLLEHQAVHTGDK--------- 511

Query: 462 SERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSG-PSGPSDGS 520
                  +F C  CG  F    +  +HR  H+            +  + S         +
Sbjct: 512 -------SFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHT 564

Query: 521 AQQIFSCKHCPSTFFSSPGLTRHINKCHPSE 551
            ++ F+C  C   F   P LT+H+ + H  E
Sbjct: 565 GERPFACAECGKAFRQRPTLTQHL-RVHTGE 594


>gi|37622345 zinc finger protein 42 isoform 1 [Homo sapiens]
          Length = 734

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 75/313 (23%), Positives = 106/313 (33%), Gaps = 53/313 (16%)

Query: 246 PGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPAN 305
           PGA      G+  P G F C  C+E +A    L +H+        + C EC + F   + 
Sbjct: 468 PGAKPPAPPGAPEPPGPFPCSECRESFARRAVLLEHQAVHTGDKSFGCVECGERFGRRSV 527

Query: 306 LASHRRWHK-PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTAD 364
           L  HRR H   RP A   A    +  +  + +      +G      AE  +  R   T  
Sbjct: 528 LLQHRRVHSGERPFA--CAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQRPTLT 585

Query: 365 QHPQARDSSGADQHPDSAPR--QGLQVLTHPEPPLPQGPYTEGVLGRR-VPVPGSTSGGR 421
           QH +          P+   R  Q L++  H      + PY  G  G     V   T   R
Sbjct: 586 QHLRVHTGEKPFACPECGQRFSQRLKLTRHQRTHTGEKPYHCGECGLGFTQVSRLTEHQR 645

Query: 422 ---GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAH 478
              G   F CP C + FR+ A L +H   H              ER     +ACP CG  
Sbjct: 646 IHTGERPFACPECGQSFRQHANLTQHRRIHT------------GER----PYACPECGKA 689

Query: 479 FPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSP 538
           F       +H   H                             ++ F+C+ C   F  S 
Sbjct: 690 FRQRPTLTQHLRTH---------------------------RREKPFACQDCGRRFHQST 722

Query: 539 GLTRHINKCHPSE 551
            L +H  + H +E
Sbjct: 723 KLIQH-QRVHSAE 734



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 68/306 (22%), Positives = 102/306 (33%), Gaps = 56/306 (18%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANA 322
           F+C  C + +     L +HR        +RC EC + F   +NL  H+R H   P     
Sbjct: 412 FVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGPGAK 471

Query: 323 ATVSSADGKPPSS-SSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDS 381
                   +PP     S  R+S A  + L E     +   T D+      S G  +  + 
Sbjct: 472 PPAPPGAPEPPGPFPCSECRESFARRAVLLE----HQAVHTGDK------SFGCVECGER 521

Query: 382 APRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRR 437
             R+ + +L H      + P+     G+      + +  R    G   F C  C K FR+
Sbjct: 522 FGRRSV-LLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHTGERPFACAECGKAFRQ 580

Query: 438 QAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREE 497
           +  L +HL  H                     FACP CG  F       +H+  H     
Sbjct: 581 RPTLTQHLRVHTGEK----------------PFACPECGQRFSQRLKLTRHQRTH----- 619

Query: 498 LLLPALAGAPPETSGPSGPSDGSAQQI------------FSCKHCPSTFFSSPGLTRHIN 545
                  G  P   G  G       ++            F+C  C  +F     LT+H  
Sbjct: 620 ------TGEKPYHCGECGLGFTQVSRLTEHQRIHTGERPFACPECGQSFRQHANLTQH-R 672

Query: 546 KCHPSE 551
           + H  E
Sbjct: 673 RIHTGE 678



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 60/271 (22%), Positives = 93/271 (34%), Gaps = 44/271 (16%)

Query: 292 RCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSS-------SSSRDSG 344
           RC  C KVFS  +NL  H++ H           V S  G+  S SS       + + +  
Sbjct: 357 RCDVCGKVFSQRSNLLRHQKIH-----TGERPFVCSECGRSFSRSSHLLRHQLTHTEERP 411

Query: 345 AIASFLAEG-KENSRIERTADQHPQARDSSGADQHPDSAPRQGL--QVLTHPEPPLPQGP 401
            +     +G   ++R+E     H   +    A+       R  L      H +PP P   
Sbjct: 412 FVCGDCGQGFVRSARLEEHRRVHTGEQPFRCAECGQSFRQRSNLLQHQRIHGDPPGP--- 468

Query: 402 YTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFG 461
                 G + P P       G   F C  C + F R+A L +H + H             
Sbjct: 469 ------GAKPPAPPGAPEPPGP--FPCSECRESFARRAVLLEHQAVHTGDK--------- 511

Query: 462 SERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSG-PSGPSDGS 520
                  +F C  CG  F    +  +HR  H+            +  + S         +
Sbjct: 512 -------SFGCVECGERFGRRSVLLQHRRVHSGERPFACAECGQSFRQRSNLTQHRRIHT 564

Query: 521 AQQIFSCKHCPSTFFSSPGLTRHINKCHPSE 551
            ++ F+C  C   F   P LT+H+ + H  E
Sbjct: 565 GERPFACAECGKAFRQRPTLTQHL-RVHTGE 594


>gi|40807465 zinc finger protein 341 [Homo sapiens]
          Length = 847

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 93/472 (19%), Positives = 145/472 (30%), Gaps = 105/472 (22%)

Query: 102 PGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPTP- 160
           P P P P P P +P           + L  P      PGG   V  +S +   A + T  
Sbjct: 183 PPPPPLPPPPPPQPPPPP------PQSLGPP--GRPNPGGNGVVEVYSAAAPLAGSGTVE 234

Query: 161 ----GEQFLLPLRAPFP--EPALQPDPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAA 214
               G Q   PL  P    EP + P P   S   Q  K          AP   A+G   A
Sbjct: 235 IQALGMQPYPPLEVPNQCVEPPVYPTPTVYSPGKQGFKPKGPNPA---APMTSATGGTVA 291

Query: 215 GIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYAD 274
               P  ++                           R     +    +  C  C + +  
Sbjct: 292 TFDSPATLKT-------------------------RRAKAAGKPKAQKLKCSYCDKSFTK 326

Query: 275 PFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPS 334
            F L QH  S      ++C  C + F+  +N+  H + HK  P   +  TVS        
Sbjct: 327 NFDLQQHIRSHTGEKPFQCIACGRAFAQKSNVKKHMQTHKVWPPGHSGGTVSRNSVTVQV 386

Query: 335 SSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPE 394
            + + SR          E +E++ + +     PQ +  S A +     P     VL    
Sbjct: 387 MALNPSRQ---------EDEESTGLGQPLPGAPQPQALSTAGEEEGDKPESKQVVLI--- 434

Query: 395 PPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGS-- 452
                                          ++C +C  KF     L+ H++ H+     
Sbjct: 435 ----------------------------DSSYLCQFCPSKFSTYFQLKSHMTQHKNEQVY 466

Query: 453 ---ARALAPGFG---------SERGAPLAFACPLCGAHFPTADIREKHRLWHAV------ 494
               ++ A  F                L++ C LCG  FP+      H+  H++      
Sbjct: 467 KCVVKSCAQTFPKLDTFLEHIKSHQEELSYRCHLCGKDFPSLYDLGVHQYSHSLLPQHSP 526

Query: 495 REELLLPALAGAPPETSGPSGPSD--GSAQQIFSCKHCPSTFFSSPGLTRHI 544
           +++  +        + S P        +A   F C HC   F     L RH+
Sbjct: 527 KKDNAVYKCVKCVNKYSTPEALEHHLQTATHNFPCPHCQKVFPCERYLRRHL 578



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 34/136 (25%), Positives = 50/136 (36%), Gaps = 18/136 (13%)

Query: 426 FVCPYCHKKFRRQAYLRKHLSTHEAG---SARALAPGFGSERGAPL---------AFACP 473
           F CP+C K F  + YLR+HL TH +G     +     F  E    L          + C 
Sbjct: 559 FPCPHCQKVFPCERYLRRHLPTHGSGGRFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCS 618

Query: 474 LCGAHFPTADIREKHRLWHAVREELLLP--ALAGAPPETSGPSGPS----DGSAQQIFSC 527
           +C + F   D  ++H L H   ++   P     G   E + P          S  ++  C
Sbjct: 619 VCESAFNRKDKLKRHMLIHEPFKKYKCPFSTHTGCSKEFNRPDKLKAHILSHSGMKLHKC 678

Query: 528 KHCPSTFFSSPGLTRH 543
             C  +F     L  H
Sbjct: 679 ALCSKSFSRRAHLAEH 694



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 2/49 (4%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           C  C  +Y+ P AL  H   +     + CP C KVF C   L  H   H
Sbjct: 535 CVKCVNKYSTPEALEHHL--QTATHNFPCPHCQKVFPCERYLRRHLPTH 581



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 19/67 (28%), Positives = 27/67 (40%), Gaps = 6/67 (8%)

Query: 249 PSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLAS 308
           P+ G GG       F CQ+CK+ +     L  H         Y+C  C+  F+    L  
Sbjct: 579 PTHGSGG------RFKCQVCKKFFRREHYLKLHAHIHSGEKPYKCSVCESAFNRKDKLKR 632

Query: 309 HRRWHKP 315
           H   H+P
Sbjct: 633 HMLIHEP 639



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 15/46 (32%), Positives = 23/46 (50%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHR 310
           C LC + ++    LA+H+ +     ++RC  C K FS    L  HR
Sbjct: 678 CALCSKSFSRRAHLAEHQRAHTGNYKFRCAGCAKGFSRHKYLKDHR 723



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 16/46 (34%), Positives = 23/46 (50%)

Query: 268 CKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           C +++  P  L  H  S      ++C  C K FS  A+LA H+R H
Sbjct: 653 CSKEFNRPDKLKAHILSHSGMKLHKCALCSKSFSRRAHLAEHQRAH 698


>gi|187761351 growth factor independent 1 [Homo sapiens]
          Length = 422

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 124/467 (26%), Positives = 166/467 (35%), Gaps = 70/467 (14%)

Query: 1   MPRGFLVKRTKRTGGLYRVRLAERVFPLLGPQGAPPFLEEAPSASLPGAERATPPTREEP 60
           MPR FLVK +K+    ++ R     + L       P    A S S  G  +A P  R  P
Sbjct: 1   MPRSFLVK-SKKAHSYHQPRSPGPDYSLRLENVPAP--SRADSTSNAGGAKAEPRDRLSP 57

Query: 61  GKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAEL 120
              LT EA    S SP    G            WR        PSPS SP+  K     L
Sbjct: 58  ESQLT-EAPDRASASPDSCEGSVCERSSEFEDFWRP-------PSPSASPASEKSMCPSL 109

Query: 121 RRAFLERCLSSPVSAESFPGGAAA-VAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQP 179
             A   +    P    S+ G A + +     S  P  A   G    L     F EPA +P
Sbjct: 110 DEA---QPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGL-----FCEPAPEP 161

Query: 180 DPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGL 239
                 AAL   KRAAGG   G AP  C++G  A                  T  P LGL
Sbjct: 162 GHP---AALYGPKRAAGGAGAG-APGSCSAGAGA------------------TAGPGLGL 199

Query: 240 KIKEEEPGAPSRGLGGSRTPLGEFICQ-----LCKEQYADPFALAQHRCSRIVRV--EYR 292
                + G+ + GL    T     +       L  ++ A     ++  C+R++     Y+
Sbjct: 200 Y---GDFGSAAAGLYERPTAAAGLLYPERGHGLHADKGAGVKVESELLCTRLLLGGGSYK 256

Query: 293 CPECDKVFSCPANLASH-RRWHK-PRPAAANAA------TVSSADGKPPSSSSSSSRDSG 344
           C +C KVFS P  L  H RR H   RP A           VS    K   S   S     
Sbjct: 257 CIKCSKVFSTPHGLEVHVRRSHSGTRPFACEMCGKTFGHAVSLEQHKAVHSQERSFDCKI 316

Query: 345 AIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTE 404
              SF      ++ +   +D  P      G   H  S  ++   + T  +P   Q     
Sbjct: 317 CGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQ----- 371

Query: 405 GVLGRRVPVPGS----TSGGRGSEIFVCPYCHKKFRRQAYLRKHLST 447
            V G+      +    +    G + F C  C K F+R+  LR+H  T
Sbjct: 372 -VCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRET 417



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 25/86 (29%), Positives = 31/86 (36%), Gaps = 19/86 (22%)

Query: 408 GRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAP 467
           G  V V  S SG R    F C  C K F     L +H + H              ER   
Sbjct: 269 GLEVHVRRSHSGTRP---FACEMCGKTFGHAVSLEQHKAVH------------SQER--- 310

Query: 468 LAFACPLCGAHFPTADIREKHRLWHA 493
            +F C +CG  F  +     H L H+
Sbjct: 311 -SFDCKICGKSFKRSSTLSTHLLIHS 335


>gi|187761349 growth factor independent 1 [Homo sapiens]
          Length = 422

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 124/467 (26%), Positives = 166/467 (35%), Gaps = 70/467 (14%)

Query: 1   MPRGFLVKRTKRTGGLYRVRLAERVFPLLGPQGAPPFLEEAPSASLPGAERATPPTREEP 60
           MPR FLVK +K+    ++ R     + L       P    A S S  G  +A P  R  P
Sbjct: 1   MPRSFLVK-SKKAHSYHQPRSPGPDYSLRLENVPAP--SRADSTSNAGGAKAEPRDRLSP 57

Query: 61  GKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAEL 120
              LT EA    S SP    G            WR        PSPS SP+  K     L
Sbjct: 58  ESQLT-EAPDRASASPDSCEGSVCERSSEFEDFWRP-------PSPSASPASEKSMCPSL 109

Query: 121 RRAFLERCLSSPVSAESFPGGAAA-VAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQP 179
             A   +    P    S+ G A + +     S  P  A   G    L     F EPA +P
Sbjct: 110 DEA---QPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGL-----FCEPAPEP 161

Query: 180 DPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGL 239
                 AAL   KRAAGG   G AP  C++G  A                  T  P LGL
Sbjct: 162 GHP---AALYGPKRAAGGAGAG-APGSCSAGAGA------------------TAGPGLGL 199

Query: 240 KIKEEEPGAPSRGLGGSRTPLGEFICQ-----LCKEQYADPFALAQHRCSRIVRV--EYR 292
                + G+ + GL    T     +       L  ++ A     ++  C+R++     Y+
Sbjct: 200 Y---GDFGSAAAGLYERPTAAAGLLYPERGHGLHADKGAGVKVESELLCTRLLLGGGSYK 256

Query: 293 CPECDKVFSCPANLASH-RRWHK-PRPAAANAA------TVSSADGKPPSSSSSSSRDSG 344
           C +C KVFS P  L  H RR H   RP A           VS    K   S   S     
Sbjct: 257 CIKCSKVFSTPHGLEVHVRRSHSGTRPFACEMCGKTFGHAVSLEQHKAVHSQERSFDCKI 316

Query: 345 AIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTE 404
              SF      ++ +   +D  P      G   H  S  ++   + T  +P   Q     
Sbjct: 317 CGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQ----- 371

Query: 405 GVLGRRVPVPGS----TSGGRGSEIFVCPYCHKKFRRQAYLRKHLST 447
            V G+      +    +    G + F C  C K F+R+  LR+H  T
Sbjct: 372 -VCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRET 417



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 25/86 (29%), Positives = 31/86 (36%), Gaps = 19/86 (22%)

Query: 408 GRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAP 467
           G  V V  S SG R    F C  C K F     L +H + H              ER   
Sbjct: 269 GLEVHVRRSHSGTRP---FACEMCGKTFGHAVSLEQHKAVH------------SQER--- 310

Query: 468 LAFACPLCGAHFPTADIREKHRLWHA 493
            +F C +CG  F  +     H L H+
Sbjct: 311 -SFDCKICGKSFKRSSTLSTHLLIHS 335


>gi|71037377 growth factor independent 1 [Homo sapiens]
          Length = 422

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 124/467 (26%), Positives = 166/467 (35%), Gaps = 70/467 (14%)

Query: 1   MPRGFLVKRTKRTGGLYRVRLAERVFPLLGPQGAPPFLEEAPSASLPGAERATPPTREEP 60
           MPR FLVK +K+    ++ R     + L       P    A S S  G  +A P  R  P
Sbjct: 1   MPRSFLVK-SKKAHSYHQPRSPGPDYSLRLENVPAP--SRADSTSNAGGAKAEPRDRLSP 57

Query: 61  GKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAEL 120
              LT EA    S SP    G            WR        PSPS SP+  K     L
Sbjct: 58  ESQLT-EAPDRASASPDSCEGSVCERSSEFEDFWRP-------PSPSASPASEKSMCPSL 109

Query: 121 RRAFLERCLSSPVSAESFPGGAAA-VAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQP 179
             A   +    P    S+ G A + +     S  P  A   G    L     F EPA +P
Sbjct: 110 DEA---QPFPLPFKPYSWSGLAGSDLRHLVQSYRPCGALERGAGLGL-----FCEPAPEP 161

Query: 180 DPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGL 239
                 AAL   KRAAGG   G AP  C++G  A                  T  P LGL
Sbjct: 162 GHP---AALYGPKRAAGGAGAG-APGSCSAGAGA------------------TAGPGLGL 199

Query: 240 KIKEEEPGAPSRGLGGSRTPLGEFICQ-----LCKEQYADPFALAQHRCSRIVRV--EYR 292
                + G+ + GL    T     +       L  ++ A     ++  C+R++     Y+
Sbjct: 200 Y---GDFGSAAAGLYERPTAAAGLLYPERGHGLHADKGAGVKVESELLCTRLLLGGGSYK 256

Query: 293 CPECDKVFSCPANLASH-RRWHK-PRPAAANAA------TVSSADGKPPSSSSSSSRDSG 344
           C +C KVFS P  L  H RR H   RP A           VS    K   S   S     
Sbjct: 257 CIKCSKVFSTPHGLEVHVRRSHSGTRPFACEMCGKTFGHAVSLEQHKAVHSQERSFDCKI 316

Query: 345 AIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTE 404
              SF      ++ +   +D  P      G   H  S  ++   + T  +P   Q     
Sbjct: 317 CGKSFKRSSTLSTHLLIHSDTRPYPCQYCGKRFHQKSDMKKHTFIHTGEKPHKCQ----- 371

Query: 405 GVLGRRVPVPGS----TSGGRGSEIFVCPYCHKKFRRQAYLRKHLST 447
            V G+      +    +    G + F C  C K F+R+  LR+H  T
Sbjct: 372 -VCGKAFSQSSNLITHSRKHTGFKPFGCDLCGKGFQRKVDLRRHRET 417



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 25/86 (29%), Positives = 31/86 (36%), Gaps = 19/86 (22%)

Query: 408 GRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAP 467
           G  V V  S SG R    F C  C K F     L +H + H              ER   
Sbjct: 269 GLEVHVRRSHSGTRP---FACEMCGKTFGHAVSLEQHKAVH------------SQER--- 310

Query: 468 LAFACPLCGAHFPTADIREKHRLWHA 493
            +F C +CG  F  +     H L H+
Sbjct: 311 -SFDCKICGKSFKRSSTLSTHLLIHS 335


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 66/248 (26%), Positives = 91/248 (36%), Gaps = 46/248 (18%)

Query: 96  AGGREGPGPSPSPSPS-------------------PAKPAGAELRRAFLERCLSSPVSAE 136
           A     PGP+PS  P                    PA PA  E  +      LS P S  
Sbjct: 245 AAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQP-----LSRPESGA 299

Query: 137 SFPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPDP----APLSAALQSLK 192
           S PGG A  +A     AP+AAP P      P  AP P+ A    P     P + A  SL 
Sbjct: 300 STPGGPAEPSA---PAAPSAAPAPAA----PAPAPAPQSAASSQPQSASTPPALAPGSLL 352

Query: 193 RAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRG 252
            AA G      P+      +A+G+  P  +  +S A        L   +K  +   P+  
Sbjct: 353 GAAPG-----LPSPLLPQTSASGVIFPNPL--VSIAATANALDPLSALMKHRKGKPPNVS 405

Query: 253 L----GGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLAS 308
           +      +  P  +  C+ C + +    AL  H  S      ++C  C   FS   NL  
Sbjct: 406 VFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNICGNRFSTKGNLKV 465

Query: 309 HRRWHKPR 316
           H + HK +
Sbjct: 466 HFQRHKEK 473



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 70/324 (21%), Positives = 106/324 (32%), Gaps = 44/324 (13%)

Query: 136  ESFPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPDPAPLSAALQSLKRAA 195
            ES   G+ A++  S S A + AP+ GE F    ++P      +P   PL         AA
Sbjct: 887  ESRSAGSPALSESSSSQALSPAPSNGESF--RSKSPGLGAPEEPQEIPLKTERPDSPAAA 944

Query: 196  GGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGG 255
             G             P  AGIK+               +P   L +  E    PS     
Sbjct: 945  PGS---------GGAPGRAGIKE--------------EAPFSLLFLSRERGKCPST---- 977

Query: 256  SRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKP 315
                    +C +C + +A   AL  H  S      + C  C +  S   NL  H   H+ 
Sbjct: 978  --------VCGVCGKPFACKSALEIHYRSHTKERPFVCALCRRGCSTMGNLKQHLLTHRL 1029

Query: 316  RPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGA 375
            +   +     + A G  PS S+ S   S A      E   + +      + P        
Sbjct: 1030 KELPSQLFDPNFALG--PSQSTPSLISSAAPTMIKMEVNGHGK-AMALGEGPPLPAGVQV 1086

Query: 376  DQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTS----GGRGSEIFVCPYC 431
               P +    GL  +  P P      +     G+      +         G + F C  C
Sbjct: 1087 PAGPQTVMGPGLAPMLAPPPRRTPKQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTIC 1146

Query: 432  HKKFRRQAYLRKHLSTHEAGSARA 455
             + F  +  L+ H+ TH   +A A
Sbjct: 1147 GRAFTTKGNLKVHMGTHMWNNAPA 1170



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 116/561 (20%), Positives = 184/561 (32%), Gaps = 80/561 (14%)

Query: 27  PLLGPQGAPPFLEEAPSASLPGAER----ATPPTREEPGKGLTAEAAREQSGSPCRAAGV 82
           P L P  AP     APS  LPG       A  P     G G  A AA E +    R    
Sbjct: 240 PSLSPAAAPSAPGPAPS-QLPGLAALPLSAGAPAAAIAGSGPAAPAAFEGAQPLSRPESG 298

Query: 83  SPGTGGREGAEWRAGGREGPGPS-PSPSPSPAKPAGAELRRAFLERCLS----------- 130
           +   GG       A     P P+ P+P+P+P   A ++ + A     L+           
Sbjct: 299 ASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLGAAPGL 358

Query: 131 -SPVSAES------FPGGAAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPDPA- 182
            SP+  ++      FP    ++AA + ++ P +A     +   P  + F   A   DP  
Sbjct: 359 PSPLLPQTSASGVIFPNPLVSIAATANALDPLSALMKHRKGKPPNVSVFEPKASAEDPFF 418

Query: 183 -----------PLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEV 231
                         +ALQ   R+  GER  K    C +  +  G  K    R       +
Sbjct: 419 KHKCRFCAKVFGSDSALQIHLRSHTGERPFKCNI-CGNRFSTKGNLKVHFQRHKEKYPHI 477

Query: 232 TTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEY 291
             +P    +  +  P       G S  P       L  +       L     S  +++  
Sbjct: 478 QMNPYPVPEYLDNVPTCSGIPYGMSLPPEKPVTTWLDSKP-----VLPTVPTSVGLQLPP 532

Query: 292 RCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIAS--- 348
             P        P+   + R   +P PA++  A++S       S  S+++    ++     
Sbjct: 533 TVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVSATAESPQSLLGGPP 592

Query: 349 -FLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQ----GLQVLTHP-EPPLPQGPY 402
              AE          A   P    +S A    D AP      GL  ++   +   P G  
Sbjct: 593 LTKAEPVSLPCTNARAGDAPVGAQASAAPTSVDGAPTSLGSPGLPAVSEQFKAQFPFGGL 652

Query: 403 TEGVLGR---RVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAG-------S 452
            + +      ++         + ++   C  CH+    Q+ L+ H  TH           
Sbjct: 653 LDSMQTSETSKLQQLVENIDKKMTDPNQCVICHRVLSCQSALKMHYRTHTGERPFKCKIC 712

Query: 453 ARA------LAPGFGSERGAP---LAFACPLCGAHFPTADIREKHRLWHAVREELLLPAL 503
            RA      L   FG  R  P   +  +CP+C   F  A + ++H   H          +
Sbjct: 713 GRAFTTKGNLKTHFGVHRAKPPLRVQHSCPICQKKFTNAVVLQQHIRMH----------M 762

Query: 504 AGAPPETSGPSGPSDGSAQQI 524
            G  P T  P G  D    ++
Sbjct: 763 GGQIPNTPLPEGFQDAMDSEL 783



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 15/45 (33%), Positives = 20/45 (44%), Gaps = 2/45 (4%)

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSA--RALAPGFGSERGAPLAF 470
           CP C KKF     L++H+  H  G      L  GF     + LA+
Sbjct: 741 CPICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAY 785


>gi|38348236 zinc finger protein 497 [Homo sapiens]
          Length = 498

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 75/307 (24%), Positives = 97/307 (31%), Gaps = 41/307 (13%)

Query: 260 LGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHK-PRPA 318
           L  F C  C + +     L QHR +      Y CPEC K FS  +N   HRR H   RP 
Sbjct: 187 LKPFRCPDCGKSFGRSTTLVQHRRTHTGEKPYECPECGKAFSWNSNFLEHRRVHTGARPH 246

Query: 319 AANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKEN--SRIERTADQHPQARDSSGAD 376
           A          GK  S SS+ +      A        +      R A      R  S   
Sbjct: 247 ACRDC------GKAFSQSSNLAEHLKIHAGARPHACPDCGKAFVRVAGLRQHRRTHSSEK 300

Query: 377 QHP----DSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR----GSEIFVC 428
             P      A R+  Q+L H      + P+     G+   +    +  R    G +   C
Sbjct: 301 PFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAFVMGSYLAEHRRVHTGEKPHAC 360

Query: 429 PYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKH 488
             C K   +++ L  H  TH                     FAC  CG  F  +     H
Sbjct: 361 AQCGKASSQRSNLLSHRRTHSGAK----------------PFACADCGKAFRGSSGLAHH 404

Query: 489 RLWHAVREELLLPALAGAPPETSGPSGPSD----GSAQQIFSCKHCPSTFFSSPGLTRHI 544
           RL H         A A       G S         S ++ F C HC   F     L  H 
Sbjct: 405 RLSHTGERPF---ACAECGKAFRGSSELRQHQRLHSGERPFVCAHCSKAFVRKSELLSH- 460

Query: 545 NKCHPSE 551
            + H  E
Sbjct: 461 RRTHTGE 467



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 72/301 (23%), Positives = 99/301 (32%), Gaps = 26/301 (8%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHK-PRPAAANAA 323
           C  C + ++    L QHR        Y CPEC K F+  +NL+ H+R H   +P A    
Sbjct: 108 CGECGKAFSQGSYLLQHRRVHTGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYACREC 167

Query: 324 TVSSADGKPPSSSSSSSRDSGAIASFLAE--GKENSRIERTADQHPQARDSSGADQHPD- 380
             +    +  S           +  F     GK   R   T  QH +        + P+ 
Sbjct: 168 GKAF---RAQSQLIHHQETHSGLKPFRCPDCGKSFGR-STTLVQHRRTHTGEKPYECPEC 223

Query: 381 -SAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSG----GRGSEIFVCPYCHKKF 435
             A       L H        P+     G+      + +       G+    CP C K F
Sbjct: 224 GKAFSWNSNFLEHRRVHTGARPHACRDCGKAFSQSSNLAEHLKIHAGARPHACPDCGKAF 283

Query: 436 RRQAYLRKHLSTH---------EAGSA-RALAPGFGSER--GAPLAFACPLCGAHFPTAD 483
            R A LR+H  TH         E G A R  +     +R       F C  CG  F    
Sbjct: 284 VRVAGLRQHRRTHSSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQAFVMGS 343

Query: 484 IREKHRLWHAVREELLLPALAGAPPETSG-PSGPSDGSAQQIFSCKHCPSTFFSSPGLTR 542
              +HR  H   +         A  + S   S     S  + F+C  C   F  S GL  
Sbjct: 344 YLAEHRRVHTGEKPHACAQCGKASSQRSNLLSHRRTHSGAKPFACADCGKAFRGSSGLAH 403

Query: 543 H 543
           H
Sbjct: 404 H 404



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 40/165 (24%), Positives = 56/165 (33%), Gaps = 21/165 (12%)

Query: 385 QGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRRQAY 440
           QG  +L H      + PYT    G+      + S  +    G + + C  C K FR Q+ 
Sbjct: 117 QGSYLLQHRRVHTGEKPYTCPECGKAFAWSSNLSQHQRIHSGEKPYACRECGKAFRAQSQ 176

Query: 441 LRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLL 500
           L  H  TH       L P           F CP CG  F  +    +HR  H   +    
Sbjct: 177 LIHHQETHS-----GLKP-----------FRCPDCGKSFGRSTTLVQHRRTHTGEKPYEC 220

Query: 501 PALAGAPPETSG-PSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHI 544
           P    A    S         +  +  +C+ C   F  S  L  H+
Sbjct: 221 PECGKAFSWNSNFLEHRRVHTGARPHACRDCGKAFSQSSNLAEHL 265



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 54/207 (26%), Positives = 76/207 (36%), Gaps = 27/207 (13%)

Query: 250 SRGLGGSRTPLGE--FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLA 307
           S+ L   RT  GE  F C  C + +     LA+HR        + C +C K  S  +NL 
Sbjct: 315 SQLLQHQRTHTGERPFECAECGQAFVMGSYLAEHRRVHTGEKPHACAQCGKASSQRSNLL 374

Query: 308 SHRRWHKPRPAAANAATVSSAD-GKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQH 366
           SHRR H      + A   + AD GK    SS               G  + R+  T ++ 
Sbjct: 375 SHRRTH------SGAKPFACADCGKAFRGSS---------------GLAHHRLSHTGER- 412

Query: 367 PQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIF 426
           P A    G      S  RQ  Q L   E P      ++  + R+  +        G   +
Sbjct: 413 PFACAECGKAFRGSSELRQH-QRLHSGERPFVCAHCSKAFV-RKSELLSHRRTHTGERPY 470

Query: 427 VCPYCHKKFRRQAYLRKHLSTHEAGSA 453
            C  C K F  +  L +H   H   +A
Sbjct: 471 ACGECGKPFSHRCNLNEHQKRHGGRAA 497


>gi|212286156 zinc finger and BTB domain containing 42 [Homo
           sapiens]
          Length = 422

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 72/290 (24%), Positives = 96/290 (33%), Gaps = 69/290 (23%)

Query: 304 ANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRI---- 359
           A+L    R  K  P    AA    A G PP      S    A+   L  G    R+    
Sbjct: 148 ADLCPAARKAKLPPFGVKAALPPRASGPPPCQVPEESDQ--ALDLSLKSGPRQERVHPPC 205

Query: 360 --------ERTADQHPQARDS--SGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGR 409
                   +R     P  +D   S ++Q   S+ R       H  P  P  P  +G++  
Sbjct: 206 VLQTPLCSQRQPGAQPLVKDERDSLSEQEESSSSRS-----PHSPPKPPPVPAAKGLVVG 260

Query: 410 RVPVPGSTSGGR-----------------GSEIFVCPYCHKKFRRQAYLRKHLSTH--EA 450
             P+P S  G R                 G  + +CP C K F     L+ HLS H  E 
Sbjct: 261 LQPLPLSGEGSRELELGAGRLASEDELGPGGPLCICPLCSKLFPSSHVLQLHLSAHFRER 320

Query: 451 GSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPET 510
            S RA     G      +A  CPLCG  F      ++H   H           +G  P T
Sbjct: 321 DSTRARLSPDG------VAPTCPLCGKTFSCTYTLKRHERTH-----------SGEKPYT 363

Query: 511 SGPSGPSDGSAQQI------------FSCKHCPSTFFSSPGLTRHINKCH 548
               G S   +  +             +C+ C   F  S  L RH+ K H
Sbjct: 364 CVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRHVRKFH 413



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 66/287 (22%), Positives = 94/287 (32%), Gaps = 44/287 (15%)

Query: 42  PSASLPGAERATPPTREEPGKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRAGGREG 101
           P    PGAE A PP    P    TA+        P       P  G +     RA G   
Sbjct: 127 PGNPAPGAEPAQPPC---PWPVWTADLC------PAARKAKLPPFGVKAALPPRASG--- 174

Query: 102 PGPSPSPSPSP-----AKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAA 156
           P P   P  S      +  +G    R      L +P+ ++  PG    V     S++   
Sbjct: 175 PPPCQVPEESDQALDLSLKSGPRQERVHPPCVLQTPLCSQRQPGAQPLVKDERDSLSEQE 234

Query: 157 APTPGEQFLLPLRAPFPEPALQPDPAP--LSAALQSLKRAAGGERR-----GKAPTDCAS 209
             +         R+P   P   P PA   L   LQ L  +  G R      G+  ++   
Sbjct: 235 ESSSS-------RSPHSPPKPPPVPAAKGLVVGLQPLPLSGEGSRELELGAGRLASEDEL 287

Query: 210 GPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIK---EEEPGAPSRGLGGSRTPLGEFICQ 266
           GP       P   +         +S VL L +     E     +R       P     C 
Sbjct: 288 GPGGPLCICPLCSKLFP------SSHVLQLHLSAHFRERDSTRARLSPDGVAPT----CP 337

Query: 267 LCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           LC + ++  + L +H  +      Y C +C K F    NL+ H   H
Sbjct: 338 LCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVH 384


>gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 74/309 (23%), Positives = 106/309 (34%), Gaps = 39/309 (12%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH---KPRPAA 319
           F C  C +++     L  HR        ++CPEC K F+    L SHRR H   KP P  
Sbjct: 236 FQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCK 295

Query: 320 ------ANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSS 373
                  +   + S       S  S+    G  +  L  G + S  E T      A    
Sbjct: 296 ECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPT-----PAVPLK 350

Query: 374 GADQHPDSAPRQGLQVLTHPEPPL--PQGPYTEGVLGRRVPVPGSTSGGR----GSEIFV 427
            A + P  AP +      HP+ P+  P   Y+    GR   +       +    G   F 
Sbjct: 351 PAQEPPPGAPPE------HPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFT 404

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAP-GFGSERGAPLA-----------FACPLC 475
           C  C K F ++ +L  H   H      A    G    +G+ LA           F CP C
Sbjct: 405 CAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDC 464

Query: 476 GAHFPTADIREKHRLWHAVREELLLPALAGAPPETSG-PSGPSDGSAQQIFSCKHCPSTF 534
           G  F        HR  H   +  + P    A  + S   S     + ++ ++C  C  +F
Sbjct: 465 GKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSF 524

Query: 535 FSSPGLTRH 543
                L  H
Sbjct: 525 SQKSNLITH 533



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 11/180 (6%)

Query: 139 PGGAAAVAAFSCSVAPAAAPTPG---EQFLLPLRAPFPEPALQP-DPAPLSAALQSLKRA 194
           P  +AA    +  + PA  P PG   E    P+ AP   P+L   D    S  L+   RA
Sbjct: 336 PQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAP---PSLYSCDDCGRSFRLERFLRA 392

Query: 195 AGGERRGKAPTDCASGPAAAGIKKPK-AMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGL 253
              +  G+ P  CA      G K    A  ++   +        G +  +    A  R  
Sbjct: 393 HQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRR- 451

Query: 254 GGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
                P   F+C  C + +     LA HR        Y CP+C K FS  +NL SHRR H
Sbjct: 452 --DHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIH 509



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 78/323 (24%), Positives = 116/323 (35%), Gaps = 49/323 (15%)

Query: 235 PVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQH-RCSRIVRVEYRC 293
           P  G + +     A  R +  + TP   F C LC + +    AL  H R     +    C
Sbjct: 88  PECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIAC 147

Query: 294 PECDKVFSCPANLASH-RRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAE 352
           P+C++ F     L +H RR H P P A          G    S +   +        +AE
Sbjct: 148 PKCERRFWRRKQLRAHLRRCHPPAPEARPFIC-----GNCGRSFAQWDQLVAHKRVHVAE 202

Query: 353 GKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQ-------------VLTHPEPPLPQ 399
             E +   +     P+ R +  A +    A  +  Q             ++ H      +
Sbjct: 203 ALEEA-AAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGE 261

Query: 400 GPYTEGVLGRR-VPVPGSTSGGR---GSEIFVCPYCHKKFRRQAYLRKHLSTHE--AGSA 453
            P+     G+R    P  TS  R   G + + C  C ++FR +  L  H   H+   GSA
Sbjct: 262 RPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSA 321

Query: 454 RALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGP 513
           +A APG GS    P   A P   A  PT  +  K                A  PP  + P
Sbjct: 322 QA-APGPGS----PQLPAGPQESAAEPTPAVPLKP---------------AQEPPPGAPP 361

Query: 514 SGPSD--GSAQQIFSCKHCPSTF 534
             P D   +   ++SC  C  +F
Sbjct: 362 EHPQDPIEAPPSLYSCDDCGRSF 384



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/122 (25%), Positives = 41/122 (33%), Gaps = 39/122 (31%)

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREK 487
           CP C ++FR   +L  H   H A +               L FAC LCG  F        
Sbjct: 87  CPECGRRFRHAPFLALHRQVHAAATP-------------DLGFACHLCGQSF-------- 125

Query: 488 HRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHINKC 547
            R W A+   L   + A  P                  +C  C   F+    L  H+ +C
Sbjct: 126 -RGWVALVLHLRAHSAAKRP-----------------IACPKCERRFWRRKQLRAHLRRC 167

Query: 548 HP 549
           HP
Sbjct: 168 HP 169



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 77/367 (20%), Positives = 109/367 (29%), Gaps = 88/367 (23%)

Query: 210 GPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCK 269
           GP A G+ +P+ +   S     T    LG + +       S    G++ P     C  C+
Sbjct: 8   GPLAMGLAQPRLLSGPSQESPQT----LGKESRGLRQQGTSVAQSGAQAPGRAHRCAHCR 63

Query: 270 EQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAA------ 323
             +    AL  H      R+   CPEC + F     LA HR+ H         A      
Sbjct: 64  RHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQ 123

Query: 324 ------------TVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARD 371
                          SA  +P +      R       F    +  + + R     P+AR 
Sbjct: 124 SFRGWVALVLHLRAHSAAKRPIACPKCERR-------FWRRKQLRAHLRRCHPPAPEARP 176

Query: 372 SSGADQHPDSAPRQGLQVLTHPEPPLPQ----------GPYTEGVLGRRVPVPGSTSGGR 421
               +     A  Q  Q++ H    + +          GP   G      P PG  +  R
Sbjct: 177 FICGNCGRSFA--QWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDR 234

Query: 422 GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPT 481
               F C  C K+FR +  L  H   H              ER       CP CG  F  
Sbjct: 235 P---FQCACCGKRFRHKPNLIAHRRVHT------------GER----PHQCPECGKRFTN 275

Query: 482 ADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLT 541
                 HR  H                           + ++ + CK C   F   P L 
Sbjct: 276 KPYLTSHRRIH---------------------------TGEKPYPCKECGRRFRHKPNLL 308

Query: 542 RHINKCH 548
            H +K H
Sbjct: 309 SH-SKIH 314



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 55/268 (20%), Positives = 82/268 (30%), Gaps = 51/268 (19%)

Query: 234 SPVLGLK-IKEEEPGAP-SRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEY 291
           +P + LK  +E  PGAP          P   + C  C   +     L  H+        +
Sbjct: 344 TPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPF 403

Query: 292 RCPECDKVFSCPANLASHRRWHK-PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFL 350
            C EC K F    +L +H R H   RP A        + G   S  ++  RD      F+
Sbjct: 404 TCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQG---SHLAAHRRDHAPDRPFV 460

Query: 351 AEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRR 410
                               D   A +H          +  H      + PY     G+ 
Sbjct: 461 CP------------------DCGKAFRHKP-------YLAAHRRIHTGEKPYVCPDCGKA 495

Query: 411 VPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGA 466
                +    R    G   + CP C + F +++ L  H  +H                  
Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDG-------------- 541

Query: 467 PLAFACPLCGAHFPTADIREKHRLWHAV 494
             AF C +CG  F   +    H+  H V
Sbjct: 542 --AFCCAICGQTFDDEERLLAHQKKHDV 567


>gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 74/309 (23%), Positives = 106/309 (34%), Gaps = 39/309 (12%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH---KPRPAA 319
           F C  C +++     L  HR        ++CPEC K F+    L SHRR H   KP P  
Sbjct: 236 FQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCK 295

Query: 320 ------ANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSS 373
                  +   + S       S  S+    G  +  L  G + S  E T      A    
Sbjct: 296 ECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPT-----PAVPLK 350

Query: 374 GADQHPDSAPRQGLQVLTHPEPPL--PQGPYTEGVLGRRVPVPGSTSGGR----GSEIFV 427
            A + P  AP +      HP+ P+  P   Y+    GR   +       +    G   F 
Sbjct: 351 PAQEPPPGAPPE------HPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFT 404

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAP-GFGSERGAPLA-----------FACPLC 475
           C  C K F ++ +L  H   H      A    G    +G+ LA           F CP C
Sbjct: 405 CAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDC 464

Query: 476 GAHFPTADIREKHRLWHAVREELLLPALAGAPPETSG-PSGPSDGSAQQIFSCKHCPSTF 534
           G  F        HR  H   +  + P    A  + S   S     + ++ ++C  C  +F
Sbjct: 465 GKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSF 524

Query: 535 FSSPGLTRH 543
                L  H
Sbjct: 525 SQKSNLITH 533



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 11/180 (6%)

Query: 139 PGGAAAVAAFSCSVAPAAAPTPG---EQFLLPLRAPFPEPALQP-DPAPLSAALQSLKRA 194
           P  +AA    +  + PA  P PG   E    P+ AP   P+L   D    S  L+   RA
Sbjct: 336 PQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAP---PSLYSCDDCGRSFRLERFLRA 392

Query: 195 AGGERRGKAPTDCASGPAAAGIKKPK-AMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGL 253
              +  G+ P  CA      G K    A  ++   +        G +  +    A  R  
Sbjct: 393 HQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRR- 451

Query: 254 GGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
                P   F+C  C + +     LA HR        Y CP+C K FS  +NL SHRR H
Sbjct: 452 --DHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIH 509



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 78/323 (24%), Positives = 116/323 (35%), Gaps = 49/323 (15%)

Query: 235 PVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQH-RCSRIVRVEYRC 293
           P  G + +     A  R +  + TP   F C LC + +    AL  H R     +    C
Sbjct: 88  PECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIAC 147

Query: 294 PECDKVFSCPANLASH-RRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAE 352
           P+C++ F     L +H RR H P P A          G    S +   +        +AE
Sbjct: 148 PKCERRFWRRKQLRAHLRRCHPPAPEARPFIC-----GNCGRSFAQWDQLVAHKRVHVAE 202

Query: 353 GKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQ-------------VLTHPEPPLPQ 399
             E +   +     P+ R +  A +    A  +  Q             ++ H      +
Sbjct: 203 ALEEA-AAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGE 261

Query: 400 GPYTEGVLGRR-VPVPGSTSGGR---GSEIFVCPYCHKKFRRQAYLRKHLSTHE--AGSA 453
            P+     G+R    P  TS  R   G + + C  C ++FR +  L  H   H+   GSA
Sbjct: 262 RPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSA 321

Query: 454 RALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGP 513
           +A APG GS    P   A P   A  PT  +  K                A  PP  + P
Sbjct: 322 QA-APGPGS----PQLPAGPQESAAEPTPAVPLKP---------------AQEPPPGAPP 361

Query: 514 SGPSD--GSAQQIFSCKHCPSTF 534
             P D   +   ++SC  C  +F
Sbjct: 362 EHPQDPIEAPPSLYSCDDCGRSF 384



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/122 (25%), Positives = 41/122 (33%), Gaps = 39/122 (31%)

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREK 487
           CP C ++FR   +L  H   H A +               L FAC LCG  F        
Sbjct: 87  CPECGRRFRHAPFLALHRQVHAAATP-------------DLGFACHLCGQSF-------- 125

Query: 488 HRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHINKC 547
            R W A+   L   + A  P                  +C  C   F+    L  H+ +C
Sbjct: 126 -RGWVALVLHLRAHSAAKRP-----------------IACPKCERRFWRRKQLRAHLRRC 167

Query: 548 HP 549
           HP
Sbjct: 168 HP 169



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 77/367 (20%), Positives = 109/367 (29%), Gaps = 88/367 (23%)

Query: 210 GPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCK 269
           GP A G+ +P+ +   S     T    LG + +       S    G++ P     C  C+
Sbjct: 8   GPLAMGLAQPRLLSGPSQESPQT----LGKESRGLRQQGTSVAQSGAQAPGRAHRCAHCR 63

Query: 270 EQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAA------ 323
             +    AL  H      R+   CPEC + F     LA HR+ H         A      
Sbjct: 64  RHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQ 123

Query: 324 ------------TVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARD 371
                          SA  +P +      R       F    +  + + R     P+AR 
Sbjct: 124 SFRGWVALVLHLRAHSAAKRPIACPKCERR-------FWRRKQLRAHLRRCHPPAPEARP 176

Query: 372 SSGADQHPDSAPRQGLQVLTHPEPPLPQ----------GPYTEGVLGRRVPVPGSTSGGR 421
               +     A  Q  Q++ H    + +          GP   G      P PG  +  R
Sbjct: 177 FICGNCGRSFA--QWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDR 234

Query: 422 GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPT 481
               F C  C K+FR +  L  H   H              ER       CP CG  F  
Sbjct: 235 P---FQCACCGKRFRHKPNLIAHRRVHT------------GER----PHQCPECGKRFTN 275

Query: 482 ADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLT 541
                 HR  H                           + ++ + CK C   F   P L 
Sbjct: 276 KPYLTSHRRIH---------------------------TGEKPYPCKECGRRFRHKPNLL 308

Query: 542 RHINKCH 548
            H +K H
Sbjct: 309 SH-SKIH 314



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 55/268 (20%), Positives = 82/268 (30%), Gaps = 51/268 (19%)

Query: 234 SPVLGLK-IKEEEPGAP-SRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEY 291
           +P + LK  +E  PGAP          P   + C  C   +     L  H+        +
Sbjct: 344 TPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPF 403

Query: 292 RCPECDKVFSCPANLASHRRWHK-PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFL 350
            C EC K F    +L +H R H   RP A        + G   S  ++  RD      F+
Sbjct: 404 TCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQG---SHLAAHRRDHAPDRPFV 460

Query: 351 AEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRR 410
                               D   A +H          +  H      + PY     G+ 
Sbjct: 461 CP------------------DCGKAFRHKP-------YLAAHRRIHTGEKPYVCPDCGKA 495

Query: 411 VPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGA 466
                +    R    G   + CP C + F +++ L  H  +H                  
Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDG-------------- 541

Query: 467 PLAFACPLCGAHFPTADIREKHRLWHAV 494
             AF C +CG  F   +    H+  H V
Sbjct: 542 --AFCCAICGQTFDDEERLLAHQKKHDV 567


>gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]
          Length = 624

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 74/309 (23%), Positives = 106/309 (34%), Gaps = 39/309 (12%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH---KPRPAA 319
           F C  C +++     L  HR        ++CPEC K F+    L SHRR H   KP P  
Sbjct: 293 FQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCK 352

Query: 320 ------ANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSS 373
                  +   + S       S  S+    G  +  L  G + S  E T      A    
Sbjct: 353 ECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPT-----PAVPLK 407

Query: 374 GADQHPDSAPRQGLQVLTHPEPPL--PQGPYTEGVLGRRVPVPGSTSGGR----GSEIFV 427
            A + P  AP +      HP+ P+  P   Y+    GR   +       +    G   F 
Sbjct: 408 PAQEPPPGAPPE------HPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFT 461

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAP-GFGSERGAPLA-----------FACPLC 475
           C  C K F ++ +L  H   H      A    G    +G+ LA           F CP C
Sbjct: 462 CAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDC 521

Query: 476 GAHFPTADIREKHRLWHAVREELLLPALAGAPPETSG-PSGPSDGSAQQIFSCKHCPSTF 534
           G  F        HR  H   +  + P    A  + S   S     + ++ ++C  C  +F
Sbjct: 522 GKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSF 581

Query: 535 FSSPGLTRH 543
                L  H
Sbjct: 582 SQKSNLITH 590



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 11/180 (6%)

Query: 139 PGGAAAVAAFSCSVAPAAAPTPG---EQFLLPLRAPFPEPALQP-DPAPLSAALQSLKRA 194
           P  +AA    +  + PA  P PG   E    P+ AP   P+L   D    S  L+   RA
Sbjct: 393 PQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAP---PSLYSCDDCGRSFRLERFLRA 449

Query: 195 AGGERRGKAPTDCASGPAAAGIKKPK-AMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGL 253
              +  G+ P  CA      G K    A  ++   +        G +  +    A  R  
Sbjct: 450 HQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRR- 508

Query: 254 GGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
                P   F+C  C + +     LA HR        Y CP+C K FS  +NL SHRR H
Sbjct: 509 --DHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIH 566



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 78/323 (24%), Positives = 116/323 (35%), Gaps = 49/323 (15%)

Query: 235 PVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQH-RCSRIVRVEYRC 293
           P  G + +     A  R +  + TP   F C LC + +    AL  H R     +    C
Sbjct: 145 PECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIAC 204

Query: 294 PECDKVFSCPANLASH-RRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAE 352
           P+C++ F     L +H RR H P P A          G    S +   +        +AE
Sbjct: 205 PKCERRFWRRKQLRAHLRRCHPPAPEARPFIC-----GNCGRSFAQWDQLVAHKRVHVAE 259

Query: 353 GKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQ-------------VLTHPEPPLPQ 399
             E +   +     P+ R +  A +    A  +  Q             ++ H      +
Sbjct: 260 ALEEA-AAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGE 318

Query: 400 GPYTEGVLGRR-VPVPGSTSGGR---GSEIFVCPYCHKKFRRQAYLRKHLSTHE--AGSA 453
            P+     G+R    P  TS  R   G + + C  C ++FR +  L  H   H+   GSA
Sbjct: 319 RPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSA 378

Query: 454 RALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGP 513
           +A APG GS    P   A P   A  PT  +  K                A  PP  + P
Sbjct: 379 QA-APGPGS----PQLPAGPQESAAEPTPAVPLKP---------------AQEPPPGAPP 418

Query: 514 SGPSD--GSAQQIFSCKHCPSTF 534
             P D   +   ++SC  C  +F
Sbjct: 419 EHPQDPIEAPPSLYSCDDCGRSF 441



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/122 (25%), Positives = 41/122 (33%), Gaps = 39/122 (31%)

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREK 487
           CP C ++FR   +L  H   H A +               L FAC LCG  F        
Sbjct: 144 CPECGRRFRHAPFLALHRQVHAAATP-------------DLGFACHLCGQSF-------- 182

Query: 488 HRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHINKC 547
            R W A+   L   + A  P                  +C  C   F+    L  H+ +C
Sbjct: 183 -RGWVALVLHLRAHSAAKRP-----------------IACPKCERRFWRRKQLRAHLRRC 224

Query: 548 HP 549
           HP
Sbjct: 225 HP 226



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 77/367 (20%), Positives = 109/367 (29%), Gaps = 88/367 (23%)

Query: 210 GPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCK 269
           GP A G+ +P+ +   S     T    LG + +       S    G++ P     C  C+
Sbjct: 65  GPLAMGLAQPRLLSGPSQESPQT----LGKESRGLRQQGTSVAQSGAQAPGRAHRCAHCR 120

Query: 270 EQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAA------ 323
             +    AL  H      R+   CPEC + F     LA HR+ H         A      
Sbjct: 121 RHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQ 180

Query: 324 ------------TVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARD 371
                          SA  +P +      R       F    +  + + R     P+AR 
Sbjct: 181 SFRGWVALVLHLRAHSAAKRPIACPKCERR-------FWRRKQLRAHLRRCHPPAPEARP 233

Query: 372 SSGADQHPDSAPRQGLQVLTHPEPPLPQ----------GPYTEGVLGRRVPVPGSTSGGR 421
               +     A  Q  Q++ H    + +          GP   G      P PG  +  R
Sbjct: 234 FICGNCGRSFA--QWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDR 291

Query: 422 GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPT 481
               F C  C K+FR +  L  H   H              ER       CP CG  F  
Sbjct: 292 P---FQCACCGKRFRHKPNLIAHRRVHT------------GER----PHQCPECGKRFTN 332

Query: 482 ADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLT 541
                 HR  H                           + ++ + CK C   F   P L 
Sbjct: 333 KPYLTSHRRIH---------------------------TGEKPYPCKECGRRFRHKPNLL 365

Query: 542 RHINKCH 548
            H +K H
Sbjct: 366 SH-SKIH 371



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 55/268 (20%), Positives = 82/268 (30%), Gaps = 51/268 (19%)

Query: 234 SPVLGLK-IKEEEPGAP-SRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEY 291
           +P + LK  +E  PGAP          P   + C  C   +     L  H+        +
Sbjct: 401 TPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPF 460

Query: 292 RCPECDKVFSCPANLASHRRWHK-PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFL 350
            C EC K F    +L +H R H   RP A        + G   S  ++  RD      F+
Sbjct: 461 TCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQG---SHLAAHRRDHAPDRPFV 517

Query: 351 AEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRR 410
                               D   A +H          +  H      + PY     G+ 
Sbjct: 518 CP------------------DCGKAFRHKP-------YLAAHRRIHTGEKPYVCPDCGKA 552

Query: 411 VPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGA 466
                +    R    G   + CP C + F +++ L  H  +H                  
Sbjct: 553 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDG-------------- 598

Query: 467 PLAFACPLCGAHFPTADIREKHRLWHAV 494
             AF C +CG  F   +    H+  H V
Sbjct: 599 --AFCCAICGQTFDDEERLLAHQKKHDV 624


>gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]
          Length = 567

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 74/309 (23%), Positives = 106/309 (34%), Gaps = 39/309 (12%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH---KPRPAA 319
           F C  C +++     L  HR        ++CPEC K F+    L SHRR H   KP P  
Sbjct: 236 FQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCK 295

Query: 320 ------ANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSS 373
                  +   + S       S  S+    G  +  L  G + S  E T      A    
Sbjct: 296 ECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPT-----PAVPLK 350

Query: 374 GADQHPDSAPRQGLQVLTHPEPPL--PQGPYTEGVLGRRVPVPGSTSGGR----GSEIFV 427
            A + P  AP +      HP+ P+  P   Y+    GR   +       +    G   F 
Sbjct: 351 PAQEPPPGAPPE------HPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPFT 404

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAP-GFGSERGAPLA-----------FACPLC 475
           C  C K F ++ +L  H   H      A    G    +G+ LA           F CP C
Sbjct: 405 CAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDC 464

Query: 476 GAHFPTADIREKHRLWHAVREELLLPALAGAPPETSG-PSGPSDGSAQQIFSCKHCPSTF 534
           G  F        HR  H   +  + P    A  + S   S     + ++ ++C  C  +F
Sbjct: 465 GKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSF 524

Query: 535 FSSPGLTRH 543
                L  H
Sbjct: 525 SQKSNLITH 533



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 11/180 (6%)

Query: 139 PGGAAAVAAFSCSVAPAAAPTPG---EQFLLPLRAPFPEPALQP-DPAPLSAALQSLKRA 194
           P  +AA    +  + PA  P PG   E    P+ AP   P+L   D    S  L+   RA
Sbjct: 336 PQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAP---PSLYSCDDCGRSFRLERFLRA 392

Query: 195 AGGERRGKAPTDCASGPAAAGIKKPK-AMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGL 253
              +  G+ P  CA      G K    A  ++   +        G +  +    A  R  
Sbjct: 393 HQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRR- 451

Query: 254 GGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
                P   F+C  C + +     LA HR        Y CP+C K FS  +NL SHRR H
Sbjct: 452 --DHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQKSNLVSHRRIH 509



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 78/323 (24%), Positives = 116/323 (35%), Gaps = 49/323 (15%)

Query: 235 PVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQH-RCSRIVRVEYRC 293
           P  G + +     A  R +  + TP   F C LC + +    AL  H R     +    C
Sbjct: 88  PECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIAC 147

Query: 294 PECDKVFSCPANLASH-RRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAE 352
           P+C++ F     L +H RR H P P A          G    S +   +        +AE
Sbjct: 148 PKCERRFWRRKQLRAHLRRCHPPAPEARPFIC-----GNCGRSFAQWDQLVAHKRVHVAE 202

Query: 353 GKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQ-------------VLTHPEPPLPQ 399
             E +   +     P+ R +  A +    A  +  Q             ++ H      +
Sbjct: 203 ALEEA-AAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGE 261

Query: 400 GPYTEGVLGRR-VPVPGSTSGGR---GSEIFVCPYCHKKFRRQAYLRKHLSTHE--AGSA 453
            P+     G+R    P  TS  R   G + + C  C ++FR +  L  H   H+   GSA
Sbjct: 262 RPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSA 321

Query: 454 RALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGP 513
           +A APG GS    P   A P   A  PT  +  K                A  PP  + P
Sbjct: 322 QA-APGPGS----PQLPAGPQESAAEPTPAVPLKP---------------AQEPPPGAPP 361

Query: 514 SGPSD--GSAQQIFSCKHCPSTF 534
             P D   +   ++SC  C  +F
Sbjct: 362 EHPQDPIEAPPSLYSCDDCGRSF 384



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 31/122 (25%), Positives = 41/122 (33%), Gaps = 39/122 (31%)

Query: 428 CPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREK 487
           CP C ++FR   +L  H   H A +               L FAC LCG  F        
Sbjct: 87  CPECGRRFRHAPFLALHRQVHAAATP-------------DLGFACHLCGQSF-------- 125

Query: 488 HRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHINKC 547
            R W A+   L   + A  P                  +C  C   F+    L  H+ +C
Sbjct: 126 -RGWVALVLHLRAHSAAKRP-----------------IACPKCERRFWRRKQLRAHLRRC 167

Query: 548 HP 549
           HP
Sbjct: 168 HP 169



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 77/367 (20%), Positives = 109/367 (29%), Gaps = 88/367 (23%)

Query: 210 GPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCK 269
           GP A G+ +P+ +   S     T    LG + +       S    G++ P     C  C+
Sbjct: 8   GPLAMGLAQPRLLSGPSQESPQT----LGKESRGLRQQGTSVAQSGAQAPGRAHRCAHCR 63

Query: 270 EQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAA------ 323
             +    AL  H      R+   CPEC + F     LA HR+ H         A      
Sbjct: 64  RHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQ 123

Query: 324 ------------TVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARD 371
                          SA  +P +      R       F    +  + + R     P+AR 
Sbjct: 124 SFRGWVALVLHLRAHSAAKRPIACPKCERR-------FWRRKQLRAHLRRCHPPAPEARP 176

Query: 372 SSGADQHPDSAPRQGLQVLTHPEPPLPQ----------GPYTEGVLGRRVPVPGSTSGGR 421
               +     A  Q  Q++ H    + +          GP   G      P PG  +  R
Sbjct: 177 FICGNCGRSFA--QWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDR 234

Query: 422 GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPT 481
               F C  C K+FR +  L  H   H              ER       CP CG  F  
Sbjct: 235 P---FQCACCGKRFRHKPNLIAHRRVHT------------GER----PHQCPECGKRFTN 275

Query: 482 ADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLT 541
                 HR  H                           + ++ + CK C   F   P L 
Sbjct: 276 KPYLTSHRRIH---------------------------TGEKPYPCKECGRRFRHKPNLL 308

Query: 542 RHINKCH 548
            H +K H
Sbjct: 309 SH-SKIH 314



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 55/268 (20%), Positives = 82/268 (30%), Gaps = 51/268 (19%)

Query: 234 SPVLGLK-IKEEEPGAP-SRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEY 291
           +P + LK  +E  PGAP          P   + C  C   +     L  H+        +
Sbjct: 344 TPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTGERPF 403

Query: 292 RCPECDKVFSCPANLASHRRWHK-PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFL 350
            C EC K F    +L +H R H   RP A        + G   S  ++  RD      F+
Sbjct: 404 TCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQG---SHLAAHRRDHAPDRPFV 460

Query: 351 AEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRR 410
                               D   A +H          +  H      + PY     G+ 
Sbjct: 461 CP------------------DCGKAFRHKP-------YLAAHRRIHTGEKPYVCPDCGKA 495

Query: 411 VPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGA 466
                +    R    G   + CP C + F +++ L  H  +H                  
Sbjct: 496 FSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIRDG-------------- 541

Query: 467 PLAFACPLCGAHFPTADIREKHRLWHAV 494
             AF C +CG  F   +    H+  H V
Sbjct: 542 --AFCCAICGQTFDDEERLLAHQKKHDV 567


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 55/192 (28%), Positives = 67/192 (34%), Gaps = 23/192 (11%)

Query: 30  GPQ--GAP-PFLEEAPSASLPGAERATPPTREEPGKGLTAEAAREQSGSPCRAAGVSPGT 86
           GPQ  G P P     P+   P A +  PP     G      AA   +  P  A       
Sbjct: 101 GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160

Query: 87  GGREGAEWRAGGREGPGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVA 146
            G      RAG   GPGP P P P P KPAG              P +A++  G AA + 
Sbjct: 161 AGPAALAARAGPGPGPGPGPGPGPGPGKPAG--------------PGAAQTLNGSAALLN 206

Query: 147 AFSCSVAPAAAPTPGEQFLLPLRAP-FPEPALQPDP-----APLSAALQSLKRAAGGERR 200
           +   +    +    G   LLPL  P  P   +Q  P     AP + A  S   A      
Sbjct: 207 SHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAP 266

Query: 201 GKAPTDCASGPA 212
             AP      PA
Sbjct: 267 AAAPPPPPPAPA 278



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 60/234 (25%), Positives = 77/234 (32%), Gaps = 47/234 (20%)

Query: 27  PLLGPQGAP-PFLEEAPSASLPGAERATPPTREEPGKGLTAEAAREQSGSPCRAAGVSPG 85
           P +G    P P     P+A  P A  A PP    P     A      +G P  A  V P 
Sbjct: 242 PFVGAAAPPAPAAPSPPAAPAPAAPAAAPPP-PPPAPATLARPPGHPAGPPTAAPAVPPP 300

Query: 86  TGGREGAEWRAGGREGPGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAV 145
              + G           G +P+P+P+   PAG               VS +  PG AAA 
Sbjct: 301 AAAQNGGS--------AGAAPAPAPAAGGPAG---------------VSGQPGPGAAAA- 336

Query: 146 AAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKAPT 205
                      AP PG +   P R     P      A    A  +     G   +G  P+
Sbjct: 337 -----------APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPS 385

Query: 206 DCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTP 259
             A  P A G   P  + K   A  VT S           P A + G+  + TP
Sbjct: 386 PAAVPPPAPG--TPTGLPK-GAAGAVTQS-------LSRTPTATTSGIRATLTP 429



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 53/160 (33%), Positives = 56/160 (35%), Gaps = 18/160 (11%)

Query: 38  LEEAPSASLPGAERATPPTREEPGKGLTAEAAREQSGSPCRAAGVSPGTGGREGAEWRA- 96
           LE   +AS        P T E       A      SGSP  AAG  P     EGA   A 
Sbjct: 29  LESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPA-EGAPGAAP 87

Query: 97  ------------GGREGPGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAA 144
                       GG + PGP PSP   P  PAG     A L R      +    P  AAA
Sbjct: 88  EPPPAGRARPGGGGPQRPGP-PSPR-RPLVPAGPAPPAAKL-RPPPEGSAGSCAPVPAAA 144

Query: 145 VAAFSCSVAPAAAPTPGEQFLLPLRA-PFPEPALQPDPAP 183
             A     APA    P     L  RA P P P   P P P
Sbjct: 145 AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGP 184



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 35/120 (29%), Positives = 47/120 (39%), Gaps = 7/120 (5%)

Query: 307 ASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQH 366
           A+H     PR     AA   +      S S + +  +G  A   AEG   +  E      
Sbjct: 37  AAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAP--AEGAPGAAPE--PPPA 92

Query: 367 PQARDSSGADQHPDS-APRQGLQVLTHPEPPLPQ-GPYTEGVLGRRVPVPGSTSGGRGSE 424
            +AR   G  Q P   +PR+ L V   P PP  +  P  EG  G   PVP + +   G E
Sbjct: 93  GRARPGGGGPQRPGPPSPRRPL-VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE 151


>gi|116875834 zinc finger protein 74 [Homo sapiens]
          Length = 644

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 56/218 (25%), Positives = 76/218 (34%), Gaps = 35/218 (16%)

Query: 101 GPGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVAPAAAPT- 159
           GP P       P++  G        E  +  P+      G  A     S +   A AP  
Sbjct: 111 GPCPEWELKAVPSQQQGICKEEPAQEPIMERPLGGAQAWGRQAGALQRSQAAPWAPAPAM 170

Query: 160 ----PGEQFLLPLRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAG 215
               P E+F  PLR P       P+  PL   L + K     E R KAP    +G  A+ 
Sbjct: 171 VWDVPVEEF--PLRCPLFAQQRVPEGGPL---LDTRKNVQATEGRTKAPARLCAGENAST 225

Query: 216 IKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADP 275
             +P+   ++                         RG G      GEF+C  C + +   
Sbjct: 226 PSEPEKFPQVR----------------------RQRGAGAGE---GEFVCGECGKAFRQS 260

Query: 276 FALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
            +L  HR        Y+C EC K F+   NL  HRR H
Sbjct: 261 SSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIH 298



 Score = 37.0 bits (84), Expect = 0.048
 Identities = 17/51 (33%), Positives = 25/51 (49%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           F C  C++ +     L  H+ +      ++C +C K FSC A L  HRR H
Sbjct: 416 FKCSDCEKAFNSRSRLTLHQRTHTGEKPFKCADCGKGFSCHAYLLVHRRIH 466



 Score = 34.3 bits (77), Expect = 0.31
 Identities = 22/59 (37%), Positives = 27/59 (45%), Gaps = 2/59 (3%)

Query: 257 RTPLGE--FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           RT  GE  F C  C + ++    L  HR        ++C EC K FS  A L  HRR H
Sbjct: 436 RTHTGEKPFKCADCGKGFSCHAYLLVHRRIHSGEKPFKCNECGKAFSSHAYLIVHRRIH 494



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 16/51 (31%), Positives = 24/51 (47%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           F C  C + ++    L  HR        + C +C K FSC ++L  H+R H
Sbjct: 472 FKCNECGKAFSSHAYLIVHRRIHTGEKPFDCSQCWKAFSCHSSLIVHQRIH 522



 Score = 33.5 bits (75), Expect = 0.53
 Identities = 15/49 (30%), Positives = 22/49 (44%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           C  C++ ++    L+ H         YRC EC K F+   +L  H R H
Sbjct: 334 CSACEKAFSCSSLLSMHLRVHTGEKPYRCGECGKAFNQRTHLTRHHRIH 382



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 13/49 (26%), Positives = 21/49 (42%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           C  C + +     L +H         Y+C  C K F+C ++L  H + H
Sbjct: 362 CGECGKAFNQRTHLTRHHRIHTGEKPYQCGSCGKAFTCHSSLTVHEKIH 410



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 11/49 (22%), Positives = 24/49 (48%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           C  C   ++    L +H+        ++C +C ++F+  ++L  H+R H
Sbjct: 530 CSECGRAFSQNHCLIKHQKIHSGEKSFKCEKCGEMFNWSSHLTEHQRLH 578


>gi|146198654 zinc finger protein 768 [Homo sapiens]
          Length = 540

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 70/316 (22%), Positives = 109/316 (34%), Gaps = 52/316 (16%)

Query: 247 GAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANL 306
           G  +RG  G R      IC +C + +     L QH+        Y+C  C K FS  ++L
Sbjct: 249 GGRARGGQGPRPN----ICGICGKSFGRGSTLIQHQRIHTGEKPYKCEVCSKAFSQSSDL 304

Query: 307 ASHRRWHK-PRPAAANAATVSSAD------------GKPPSSSSSSSRDSGAIASFLAEG 353
             H+R H   RP        + AD            G+ P       +  G  +  L   
Sbjct: 305 IKHQRTHTGERPYKCPRCGKAFADSSYLLRHQRTHSGQKPYKCPHCGKAFGDSSYLLRHQ 364

Query: 354 KENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLG----- 408
           + +S       + P +    G     +S+ R      +H      Q P++ G+ G     
Sbjct: 365 RTHSH------ERPYSCTECGKCYSQNSSLR------SHQRVHTGQRPFSCGICGKSFSQ 412

Query: 409 RRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPL 468
           R   +P + S  R  + F CP C K+F + + L  H  TH  G                 
Sbjct: 413 RSALIPHARSHAR-EKPFKCPECGKRFGQSSVLAIHARTHLPGR---------------- 455

Query: 469 AFACPLCGAHFPTADIREKHRLWHAVREELLLPALA-GAPPETSGPSGPSDGSAQQIFSC 527
            ++CP CG  F  +    +H+  H             G    ++        S ++ + C
Sbjct: 456 TYSCPDCGKTFNRSSTLIQHQRSHTGERPYRCAVCGKGFCRSSTLLQHHRVHSGERPYKC 515

Query: 528 KHCPSTFFSSPGLTRH 543
             C   F  S  L RH
Sbjct: 516 DDCGKAFSQSSDLIRH 531



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 104/479 (21%), Positives = 159/479 (33%), Gaps = 58/479 (12%)

Query: 34  APPFLEEAPSASLPGAERATPPTREEPGKGLTAEAAREQSGSPCRAAGVSPGTGGREGAE 93
           +P F   +P +     E  +   R EP          +  G   R+ G  P + G E   
Sbjct: 97  SPEFAPRSPESDSQSPEFESQSPRYEP----------QSPGYEPRSPGYEPRSPGYESES 146

Query: 94  WRAGGREGPGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESFPGGAAAVAAFSCSVA 153
            R   +     + SP          E     L     SP++      G   + +F+    
Sbjct: 147 SRYESQNTELKTQSPEFEAQSSKFQEGAEMLLNPEEKSPLNISV---GVHPLDSFTQGFG 203

Query: 154 --PAAAPTPGEQFLLPLRAPFPEPALQ--PDPAPLSAALQSLKRAAGGERRGKAPTDCAS 209
             P      G  F +P  A    P  +   +P  L+ AL+   R  G  R G+ P     
Sbjct: 204 EQPTGDLPIGPPFEMPTGALLSTPQFEMLQNPLGLTGALRGPGRRGGRARGGQGPRPNIC 263

Query: 210 GPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGE--FICQL 267
           G       +   +  +      T       ++  +     S  +   RT  GE  + C  
Sbjct: 264 GICGKSFGRGSTL--IQHQRIHTGEKPYKCEVCSKAFSQSSDLIKHQRTHTGERPYKCPR 321

Query: 268 CKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHK-PRPAAANAATVS 326
           C + +AD   L +H+ +   +  Y+CP C K F   + L  H+R H   RP +       
Sbjct: 322 CGKAFADSSYLLRHQRTHSGQKPYKCPHCGKAFGDSSYLLRHQRTHSHERPYSCTECGKC 381

Query: 327 SADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQG 386
            +     SS  S  R       F       S  +R+A   P AR  S A + P   P  G
Sbjct: 382 YSQN---SSLRSHQRVHTGQRPFSCGICGKSFSQRSA-LIPHAR--SHAREKPFKCPECG 435

Query: 387 LQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLS 446
            +           G  +   +  R  +PG T        + CP C K F R + L +H  
Sbjct: 436 KRF----------GQSSVLAIHARTHLPGRT--------YSCPDCGKTFNRSSTLIQHQR 477

Query: 447 THEAGSA-RALAPGFGSERGAPL-----------AFACPLCGAHFPTADIREKHRLWHA 493
           +H      R    G G  R + L            + C  CG  F  +    +H+  HA
Sbjct: 478 SHTGERPYRCAVCGKGFCRSSTLLQHHRVHSGERPYKCDDCGKAFSQSSDLIRHQRTHA 536


>gi|24432013 zinc finger protein 668 [Homo sapiens]
          Length = 619

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 90/389 (23%), Positives = 128/389 (32%), Gaps = 49/389 (12%)

Query: 204 PTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPS-----------RG 252
           P DC+   A     KPK   +   A+E +   V G   K      P            R 
Sbjct: 46  PADCSEEVAEV---KPKPETEAK-AEEASGEKVSGSAAKPRPYACPLCPKAYKTAPELRS 101

Query: 253 LGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRW 312
            G S T    F C  C  ++  P  L  H  S    + +RC  C K +   + L  H+R 
Sbjct: 102 HGRSHTGEKPFPCPECGRRFMQPVCLRVHLASHAGELPFRCAHCPKAYGALSKLKIHQRG 161

Query: 313 HK-PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAE--GKENSRIERTADQHPQA 369
           H   RP A      S AD   PS      R    +  +  E  GK  + ++   D     
Sbjct: 162 HTGERPYACADCGKSFAD---PSVFRKHRRTHAGLRPYSCERCGKAYAELK---DLRNHE 215

Query: 370 RDSSGADQHPDSAPRQG------LQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR-- 421
           R  +G  + P      G        +  H      Q PY     G+      S       
Sbjct: 216 RSHTG--ERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERT 273

Query: 422 --GSEIFVCPYCHKKFRRQAYLRKHLSTH-EAGSARALAPGFGSERGAPLA--------- 469
             G + F+CP C + F   +  R+H   H E         G    + A LA         
Sbjct: 274 HSGEKPFLCPRCGRMFSDPSSFRRHQRAHEEVKPYHCEKCGKDFRQPADLAMHRRVHTGD 333

Query: 470 --FACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSD-GSAQQIFS 526
             F C  C   F  +   ++H L H+ +          A  E +  +  S   S ++ F 
Sbjct: 334 RPFKCLQCDKTFVASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGERPFH 393

Query: 527 CKHCPSTFFSSPGLTRHINKCHPSESRQV 555
           C  C  +F  S  L +H      SE+  V
Sbjct: 394 CNACGKSFVVSSSLRKHERTHRSSEAAGV 422



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 79/329 (24%), Positives = 127/329 (38%), Gaps = 41/329 (12%)

Query: 257 RTPLGE--FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHK 314
           RT  GE  F+C  C   ++DP +  +H+ +      Y C +C K F  PA+LA HRR H 
Sbjct: 272 RTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEEVKPYHCEKCGKDFRQPADLAMHRRVHT 331

Query: 315 -PRP---AAANAATVSSADGKPPSSSSSSSR-----DSGAIASFLAEGKENSRIERTADQ 365
             RP      +   V+S D K  +   S  R     + G   +  A   ++SR+   + +
Sbjct: 332 GDRPFKCLQCDKTFVASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVH--SGE 389

Query: 366 HPQARDSSGADQHPDSAPRQGLQVLTHPEPP-LPQGPYTEGVLGRRVPV----------- 413
            P   ++ G      S+ R+  +     E   +P  P  E V+G  +PV           
Sbjct: 390 RPFHCNACGKSFVVSSSLRKHERTHRSSEAAGVP--PAQELVVGLALPVGVAGESSAAPA 447

Query: 414 PGSTSGGRGSEIFVCP-----YCHKKFRRQAYLRKHLSTHEAGSARALAP--GFGSERGA 466
            G+  G   + +   P         +++      +H+   +AG   A  P  G G   G 
Sbjct: 448 AGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVREAPGPLEGAGEAGGE 507

Query: 467 -----PLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPS-DGS 520
                P  F C  C   F T  +  +H   H             +  + +G    S   S
Sbjct: 508 EADEKPPQFVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHS 567

Query: 521 AQQIFSCKHCPSTFFSSPGLTRHINKCHP 549
           + + ++C HCP  F S+  L +H  + HP
Sbjct: 568 SVRPYTCPHCPKAFLSASDLRKH-ERTHP 595



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 67/275 (24%), Positives = 92/275 (33%), Gaps = 42/275 (15%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAA--- 319
           F C+ C   +A+  +L +H         + C  C K F   ++L  H R H+   AA   
Sbjct: 364 FRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHERTHRSSEAAGVP 423

Query: 320 -ANAATVSSADGKPPSSSSSSSRDSGA-----IASFLAEGKENSRIERTADQ-------H 366
            A    V  A     +  SS++  +GA      A  L    E+  +  T  Q       H
Sbjct: 424 PAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVEH 483

Query: 367 PQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTE--GVLGRRVPVPGSTSGGRGSE 424
            + +D+ G  + P      G       +   PQ    E          +           
Sbjct: 484 VECQDA-GVREAPGPLEGAGEAGGEEADEKPPQFVCRECKETFSTMTLLRRHERSHPELR 542

Query: 425 IFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADI 484
            F C  C K F  +A LRKH  TH   S R               + CP C   F +A  
Sbjct: 543 PFPCTQCGKSFSDRAGLRKHSRTH--SSVR--------------PYTCPHCPKAFLSASD 586

Query: 485 REKHRLWHAVREELLLP-----ALAGAPPETSGPS 514
             KH   H V      P     AL G P E  GP+
Sbjct: 587 LRKHERTHPVPMGTPTPLEPLVALLGMPEE--GPA 619



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 36/138 (26%), Positives = 53/138 (38%), Gaps = 13/138 (9%)

Query: 183 PLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIK 242
           P+  A +S    A G   G  P      P  +G       + +    E       G++  
Sbjct: 435 PVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVR-- 492

Query: 243 EEEPGAPSRGLGGS-------RTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPE 295
            E PG P  G G +       + P  +F+C+ CKE ++    L +H  S      + C +
Sbjct: 493 -EAPG-PLEGAGEAGGEEADEKPP--QFVCRECKETFSTMTLLRRHERSHPELRPFPCTQ 548

Query: 296 CDKVFSCPANLASHRRWH 313
           C K FS  A L  H R H
Sbjct: 549 CGKSFSDRAGLRKHSRTH 566



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 18/58 (31%), Positives = 25/58 (43%)

Query: 256 SRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           S   L  F C  C + ++D   L +H  +      Y CP C K F   ++L  H R H
Sbjct: 537 SHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTH 594


>gi|116256460 zinc finger protein 775 [Homo sapiens]
          Length = 537

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 107/481 (22%), Positives = 157/481 (32%), Gaps = 110/481 (22%)

Query: 161 GEQFLLPLRAPFPEPALQPDPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPK 220
           G   ++ ++   PE  LQ   AP +  ++  K     + RG  P      P A G     
Sbjct: 11  GAGLVMKVKQEKPERLLQT-LAPQAMLVEKDKENIFQQHRGLPPRQTMGRPRALG----- 64

Query: 221 AMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPL--------GEFICQLCKEQY 272
                    E + SP       E++ G   R  G +  PL        G F+C  C +++
Sbjct: 65  -------GQEESGSPRWAPPT-EQDAGLAGRAPGSASGPLSPSLSSGEGHFVCLDCGKRF 116

Query: 273 ADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPR-----PAAANAATVSS 327
           +   +L  H+ +      Y C +C K FS   NLA H+R H        P  A   +   
Sbjct: 117 SWWSSLKIHQRTHTGEKPYLCGKCGKSFSQKPNLARHQRHHTGERPFCCPECARRFSQKQ 176

Query: 328 ADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQH---PDSAPR 384
              K   + S  +  S          +   RI + A  H + R  S A  H    D+A R
Sbjct: 177 HLLKHQKTHSRPATHSCPECERCFRHQVGLRIHQRA--HARDRQGSRAGLHELIQDAAAR 234

Query: 385 QGLQVLTHPEPPLPQGPYTE------GVLGRRVPVPGSTSGGR----------------- 421
           +  ++   P    P+  +        G  G R  V G    G                  
Sbjct: 235 RACRLQPGPPRGRPEWAWLGLCQGWWGQPGARAAVSGPEGPGEPRQFICNECGKSFTWWS 294

Query: 422 ----------GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAP----GFGSER--- 464
                     G   + CP C ++F ++  L +HL  H  G      P    GF  ++   
Sbjct: 295 SLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNH-TGERPHPCPHCGRGFRQKQHLL 353

Query: 465 --------GAPLAFACPLCGAHFPTADIREKHRLWHAVREELL-------------LPAL 503
                   GA  A  CP CG    +      H+  HAV E  +             +P L
Sbjct: 354 KHLRTHLPGAQAA-PCPSCGKSCRSRAALRAHQRAHAVAEPAVPAGEPGDQPQAEAIPGL 412

Query: 504 AGAPPETSGPSGPSD-------------GSAQQIFSCKHCPSTFFSSPGLTRHINKCHPS 550
           A  P  +    G  D             G  +Q F C  C  +F     LT H  + H  
Sbjct: 413 AARPRSSQRSPGARDTLWGRGQAGLAGPGEPRQ-FICNECGKSFSWWSALTIH-QRIHTG 470

Query: 551 E 551
           E
Sbjct: 471 E 471



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 1/67 (1%)

Query: 247 GAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANL 306
           G    GL G   P  +FIC  C + ++   AL  H+        Y CPEC + FS   NL
Sbjct: 431 GRGQAGLAGPGEPR-QFICNECGKSFSWWSALTIHQRIHTGERPYPCPECGRRFSQKPNL 489

Query: 307 ASHRRWH 313
             HRR H
Sbjct: 490 TRHRRNH 496



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 62/261 (23%), Positives = 79/261 (30%), Gaps = 54/261 (20%)

Query: 262 EFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH---KPRPA 318
           +FIC  C + +    +L  H+        Y CPEC + FS   NL  H R H   +P P 
Sbjct: 280 QFICNECGKSFTWWSSLNIHQRIHTGERPYACPECGRRFSQKPNLTRHLRNHTGERPHPC 339

Query: 319 AANA--------------ATVSSADGKPPSSSSSSSRDSGAIASFL---AEGKENSRIER 361
                               +  A   P  S   S R   A+ +     A  +       
Sbjct: 340 PHCGRGFRQKQHLLKHLRTHLPGAQAAPCPSCGKSCRSRAALRAHQRAHAVAEPAVPAGE 399

Query: 362 TADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR 421
             DQ PQA    G    P S+ R          P      +  G  G         +G  
Sbjct: 400 PGDQ-PQAEAIPGLAARPRSSQRS---------PGARDTLWGRGQAG--------LAGPG 441

Query: 422 GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPT 481
               F+C  C K F   + L  H   H              ER  P    CP CG  F  
Sbjct: 442 EPRQFICNECGKSFSWWSALTIHQRIHTG------------ERPYP----CPECGRRFSQ 485

Query: 482 ADIREKHRLWHAVREELLLPA 502
                +HR  H      L PA
Sbjct: 486 KPNLTRHRRNHTGERPYLCPA 506



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 35/148 (23%), Positives = 55/148 (37%), Gaps = 14/148 (9%)

Query: 175 PALQPDPAPLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVTTS 234
           PA +P   P + A+  L       +R     D   G   AG+  P   R+    +E   S
Sbjct: 396 PAGEPGDQPQAEAIPGLAARPRSSQRSPGARDTLWGRGQAGLAGPGEPRQF-ICNECGKS 454

Query: 235 PVLGLKIKEEEPGAPSRGLGGSRTPLGE--FICQLCKEQYADPFALAQHRCSRIVRVEYR 292
                 +   +           R   GE  + C  C  +++    L +HR +      Y 
Sbjct: 455 FSWWSALTIHQ-----------RIHTGERPYPCPECGRRFSQKPNLTRHRRNHTGERPYL 503

Query: 293 CPECDKVFSCPANLASHRRWHKPRPAAA 320
           CP C + FS   +L  H+R H+  PA +
Sbjct: 504 CPACGRGFSQKQHLLKHQRVHRAAPACS 531


>gi|215820619 zinc finger protein 646 [Homo sapiens]
          Length = 1832

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 78/307 (25%), Positives = 105/307 (34%), Gaps = 51/307 (16%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKP------RPA 318
           CQ C   Y  P +L  HR +    + + C  C K FS P  L SH R H P      RP 
Sbjct: 50  CQQCGRGYRHPGSLVNHRRTHETGL-FPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPP 108

Query: 319 AANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKEN--SRIERTAD--QHPQARDSSG 374
               AT       P     + S DS       +EG EN     E T D    P  R +SG
Sbjct: 109 RPKEAT-------PHLQGETVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASG 161

Query: 375 ADQHPDSAPRQGLQVLTHPEPPLPQ---GPYTEGVLGRRVPVPGSTSGGRGSEIFVCPYC 431
             +   +  R+GL   +HP P       GP T       +P+P S+              
Sbjct: 162 TWEDLPTRQREGL--ASHPGPEDGADGWGPSTNSARAPPLPIPASS-------------- 205

Query: 432 HKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLW 491
                 + YL + +     G     +P    ER     + C  CG  +  A     HR  
Sbjct: 206 -LLSNLEQYLAESVVNFTGGQEPTQSPPAEEER----RYKCSQCGKTYKHAGSLTNHRQS 260

Query: 492 HAVREELLLPALAGAPPETSGPSGPSDGS----AQQIFSCKHCPSTFFSSPGLTRHINKC 547
           H     L +   A    E S      + S      + + C HCP  F     L  H  + 
Sbjct: 261 HT----LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEH-QQS 315

Query: 548 HPSESRQ 554
           H  E ++
Sbjct: 316 HEGERQE 322



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 63/282 (22%), Positives = 92/282 (32%), Gaps = 64/282 (22%)

Query: 265  CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAAT 324
            C LC +++ +P A   H  + I    + CP+C K F     LASH + H    +   A  
Sbjct: 1559 CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQM 1618

Query: 325  VSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPR 384
              + D K     + +  D   +     +GK          Q   +    G  +  + A  
Sbjct: 1619 EEARDPK-----AGTGEDQVVLPG---QGKA---------QEAPSETPRGPGESVERA-- 1659

Query: 385  QGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSE---IFVCPYCHKKFRRQAYL 441
            +G Q +T       + P+     GR     GS    + +    ++ C  C K       L
Sbjct: 1660 RGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSL 1719

Query: 442  RKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLP 501
            + H  TH                  P    C +CG  F TA   E H   HA RE     
Sbjct: 1720 KNHSRTHTD----------------PKRHCCSICGKAFRTAARLEGHGRVHAPRE----- 1758

Query: 502  ALAGAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRH 543
                      GP           F+C HCP  F       +H
Sbjct: 1759 ----------GP-----------FTCPHCPRHFRRRISFVQH 1779



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 81/386 (20%), Positives = 112/386 (29%), Gaps = 115/386 (29%)

Query: 260 LGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH------ 313
           LG + C +C +++++  AL  H         Y CP C +VF  P  L  H++ H      
Sbjct: 263 LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQE 322

Query: 314 -----KPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQ 368
                K  P        SS D  P +   + S +          G E  R  R  D    
Sbjct: 323 PRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRT 382

Query: 369 ARDSSGADQHPDS-----------------------------APRQG------------- 386
            R +     H  S                              PRQG             
Sbjct: 383 YRHAGSLINHRKSHQTGVYPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAP 442

Query: 387 --LQVLTH-----PEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSE---IFVCPYCHKKFR 436
             L   TH     P   L   PY     GR     GS    R S     + C  C +K+ 
Sbjct: 443 LLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGEYQCSLCPRKYP 502

Query: 437 RQAYLRKHLSTHEAGSARA---------------LAPGFGSERGAP-------------- 467
               LR H+  H   + R+               L P       AP              
Sbjct: 503 NLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEA 562

Query: 468 ----------LAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPS 517
                      A  C +CG  F  A+  E+H L H   E+        +  ET+      
Sbjct: 563 TDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEK------ENSRTETT------ 610

Query: 518 DGSAQQIFSCKHCPSTFFSSPGLTRH 543
             S  + F+C+ C  ++  S  L  H
Sbjct: 611 -MSPPRAFACRDCGKSYRHSGSLINH 635



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 73/319 (22%), Positives = 112/319 (35%), Gaps = 79/319 (24%)

Query: 258 TPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP 317
           +P   F C+ C + Y    +L  HR +     ++ C  C K F   A + +H R H  R 
Sbjct: 612 SPPRAFACRDCGKSYRHSGSLINHRQTHQTG-DFSCGACAKHFHTMAAMKNHLRRHSRRR 670

Query: 318 AAANAATVSSADGKPPSSSSSSSRDSGAIA--SFLAEGKENSRIERTADQHPQARDSSGA 375
           +  +      A G          R++  +A  S+  E ++N  +E  + Q P      GA
Sbjct: 671 SRRHRKRAGGASG---------GREAKLLAAESWTRELEDNEGLE--SPQDPSGESPHGA 719

Query: 376 DQHPDS----------APRQGLQV-LTHPEPPLPQGPYTEGV------LGRRVPVPGSTS 418
           + + +S            + GL+   TH +     G   EG+      L   + +PG   
Sbjct: 720 EGNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEG 779

Query: 419 GGRGSEIFVCPYCHK-----KFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACP 473
           GG         +C       + ++ A  + + S+H A +        G + GA  A  C 
Sbjct: 780 GGTH-------FCDSLTGVDEDQKPATGQPNSSSHSANAVT------GWQAGA--AHTCS 824

Query: 474 LCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFSCKHCPST 533
            CG  FP A     HR  H                    P G        I+ C  CP  
Sbjct: 825 DCGHSFPHATGLLSHRPCH--------------------PPG--------IYQCSLCPKE 856

Query: 534 FFSSPGLTRHINKCHPSES 552
           F S P L  H     P E+
Sbjct: 857 FDSLPALRSHFQNHRPGEA 875



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 81/335 (24%), Positives = 113/335 (33%), Gaps = 64/335 (19%)

Query: 174  EPALQPDP-APLSAALQSLKRAAGGERRGKAPTDCASGPAAAGIKKPKAMRKLSFADEVT 232
            EP + P P A  S+ LQ      GG  + +   +   GP  A ++K +   K+   +EV 
Sbjct: 1108 EPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAE--EGPGQAEVEKLQEELKVEPLEEVA 1165

Query: 233  TSPV-----LGLKIKEEEPGAPSRGLGGSRTPLGE--FICQLCKEQYADPFALAQHRCSR 285
                       +K +E EP   +   G       E  F C++C   Y    +L  HR S 
Sbjct: 1166 RVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSH 1225

Query: 286  IVRVEYRCPECDKVFSCPANLASHRRWHK-PRPAAANAATVSSADGKPPSSSSSSSRDSG 344
                 + C  C K FS   +L +HRR H  PR                 S    + R   
Sbjct: 1226 QTG-HFGCQACSKGFSNLMSLKNHRRIHADPRRFRC-------------SECGKAFRLRK 1271

Query: 345  AIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTE 404
             +AS       + R+      H + R   G  +    A R+               P+  
Sbjct: 1272 QLAS-------HQRV------HMERRGGGGTRK----ATRE-------------DRPFRC 1301

Query: 405  GVLGRRVPVPGSTSGGRGSEI---FVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFG 461
            G  GR     GS    R S     + CP C K +  +  L+ H   H     R       
Sbjct: 1302 GQCGRTYRHAGSLLNHRRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAG---- 1357

Query: 462  SERGAPLAFACPLCGAHFPTADIREKHRLWHAVRE 496
              R    A  C LCG  FP     E+H   H   E
Sbjct: 1358 --RSRRTAVRCALCGRSFPGRGSLERHLREHEETE 1390



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 78/356 (21%), Positives = 124/356 (34%), Gaps = 69/356 (19%)

Query: 247  GAPSRGLGGSRTPLGE-----------------FICQLCKEQYADPFALAQHRCSRIVRV 289
            G  ++   G+ TPLG+                 F C  C + Y    +L  HR  +I + 
Sbjct: 1019 GGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHR--KIHQT 1076

Query: 290  -EYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIAS 348
             ++ CP C +   C  NLA++R   +  P    +       G  P ++ SS    G I  
Sbjct: 1077 GDFLCPVCSR---CYPNLAAYRNHLRNHPRCKGS---EPQVGPIPEAAGSSELQVGPIP- 1129

Query: 349  FLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHP--EPPLPQGPYTEGV 406
               EG  N + +  A++ P   +     +     P + +  +     E    +G   E  
Sbjct: 1130 ---EGGSN-KPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPR 1185

Query: 407  LGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAG--SARALAPGFGS-- 462
            L       G  +       F C  C + ++    L  H  +H+ G    +A + GF +  
Sbjct: 1186 L--ETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLM 1243

Query: 463  -------ERGAPLAFACPLCGAHFPTADIREKHRLWH-----------AVREELLLPALA 504
                       P  F C  CG  F        H+  H           A RE+   P   
Sbjct: 1244 SLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRED--RPFRC 1301

Query: 505  GAPPETSGPSGP------SDGSAQQIFSCKHCPSTFFSSPGLTRHINKCHPSESRQ 554
            G    T   +G       S  + Q  +SC  CP T+ +   L  H  + H SE+R+
Sbjct: 1302 GQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDH-QRLH-SENRR 1353



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 24/80 (30%), Positives = 29/80 (36%), Gaps = 19/80 (23%)

Query: 401 PYTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGF 460
           P+  G+L  R   P          I+ C  C K+F     LR H   H  G A +  P  
Sbjct: 831 PHATGLLSHRPCHPPG--------IYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQP-- 880

Query: 461 GSERGAPLAFACPLCGAHFP 480
                    F C LCG  FP
Sbjct: 881 ---------FLCCLCGMIFP 891



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 17/56 (30%), Positives = 23/56 (41%)

Query: 261  GEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPR 316
            G + C LC +   +  +L  H  +      + C  C K F   A L  H R H PR
Sbjct: 1702 GLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPR 1757


>gi|154744870 zinc finger protein 574 [Homo sapiens]
          Length = 896

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 62/239 (25%), Positives = 90/239 (37%), Gaps = 20/239 (8%)

Query: 101 GPGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSA-ESFPGGAA-----AVAAFSCSVAP 154
           G  P   PS   A P+   LR     RC ++   A   F  G       + A      A 
Sbjct: 632 GRQPHRCPSCGAAFPSSLRLRE---HRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAA 688

Query: 155 AAAPTPGEQFLLPLRAPFPE-PALQPDPAPLSAALQSLKRA---AGGERRGKAPTDCASG 210
            AA  PGE  +L    P P  P     P    AAL S   A   A   RRG   ++C   
Sbjct: 689 HAAAGPGE--VLAKEPPAPRAPRATRAPVASPAALGSTATASPAAPARRRGLECSECKK- 745

Query: 211 PAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFICQLCKE 270
              +     +  R++   +     P  G   ++       R L     P   F C++C +
Sbjct: 746 -LFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERP---FACEVCGK 801

Query: 271 QYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSAD 329
            +A    LA+HR        Y CP+C K +   +NL  HR+ H+ +  AA    ++ A+
Sbjct: 802 AFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEAE 860



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 49/172 (28%), Positives = 65/172 (37%), Gaps = 27/172 (15%)

Query: 154 PAAAPTPGEQFL---LPLRAPFPEPALQPDPAPLSAALQSLKR--AAGGERRGKAPTDCA 208
           PA  P   E  L   +   +P   P  QPDP P S     L+   A G +RRG+      
Sbjct: 238 PAPVPESQEPALQQEVQASSPAEVPVSQPDPLPASDHSYELRNGEAIGRDRRGRRARRNN 297

Query: 209 SGPAAAGIKKPKAMRKL--SFADEVTTSP-VLGLKIKEEEPGAPSRGLGGSRTPLGEFIC 265
           SG A        A ++L  S  D++  SP  L   ++    G               F C
Sbjct: 298 SGEAGGA-----ATQELFCSACDQLFLSPHQLQQHLRSHREGV--------------FKC 338

Query: 266 QLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP 317
            LC   +  P +L QH         + C +C   F   A L +HRR H P P
Sbjct: 339 PLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNP 390



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 71/298 (23%), Positives = 98/298 (32%), Gaps = 52/298 (17%)

Query: 291 YRCPECDKVFSCPANLASHRRWHKPRPA--AANAATVSSADGKPPSSSSSSSRDSGAIAS 348
           Y+C EC ++F  PA+   H+  H P P   +   A         P+    S  D    + 
Sbjct: 214 YKCSECSQLFQLPADFLEHQATHFPAPVPESQEPALQQEVQASSPAEVPVSQPDPLPASD 273

Query: 349 FLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLG 408
              E +    I R        R++SG       A  Q L      +  L      + +  
Sbjct: 274 HSYELRNGEAIGRDRRGRRARRNNSG---EAGGAATQELFCSACDQLFLSPHQLQQHLRS 330

Query: 409 RRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAP---GFGSE-- 463
            R              +F CP C + F   + L +HL  H + S          FG+E  
Sbjct: 331 HR------------EGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEAL 378

Query: 464 ----RGA----PLAFACPLCGAHFPTADIREKHRLWHAV-----------REELLLPALA 504
               R A    PL  +CP CG  F        HR  H V            EE ++    
Sbjct: 379 LLAHRRAHTPNPL-HSCP-CGKTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEEPVIGFPE 436

Query: 505 GAPPETSGPSGP---------SDGSAQQIFSCKHCPSTFFSSPGLTRHINKCHPSESR 553
            AP ET  P  P         +  +A   + C  C   F  +  LTRH    H  E R
Sbjct: 437 PAPAETGEPEAPEPPVSEETSAGPAAPGTYRCLLCSREFGKALQLTRHQRFVHRLERR 494



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 65/287 (22%), Positives = 94/287 (32%), Gaps = 64/287 (22%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVF-----------------------S 301
           CQ C  ++  P+ L  HR        Y+C EC + F                       S
Sbjct: 581 CQECGVRFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVHQLVVHAGRQPHRCPS 640

Query: 302 CPANLASHRRWHKPRPAAANAAT------------VSSADGKPPSSSSSSSRDSGAIASF 349
           C A   S  R  + R AAA A              V SA       ++ ++   G + + 
Sbjct: 641 CGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAK 700

Query: 350 LAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGR 409
                   R  R     P A  S+        A R+GL+     E        T   + R
Sbjct: 701 EPPAPRAPRATRAPVASPAALGSTATASPAAPARRRGLEC---SECKKLFSTETSLQVHR 757

Query: 410 RVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHE---------AGSARALAPGF 460
           R+          G   + CP C K FR+  +L+ H   H           G A A++   
Sbjct: 758 RIHT--------GERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRL 809

Query: 461 GSER---GAPLAFACPLCGAHFPTADIREKHRLWH------AVREEL 498
              R        ++CP CG  + +     KHR  H      AVR++L
Sbjct: 810 AEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQL 856



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 65/308 (21%), Positives = 93/308 (30%), Gaps = 62/308 (20%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAAT 324
           C +C + +     +  H  +      + CP+C K F+ PANLA HR  H           
Sbjct: 497 CSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTH------TGERP 550

Query: 325 VSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPR 384
               D     + SS+ R    +                A   P      G   H      
Sbjct: 551 YRCGDCGKAFTQSSTLRQHRLV---------------HAQHFPYRCQECGVRFH------ 589

Query: 385 QGLQVLTHPEPPLPQGPY-----TEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQA 439
           +  ++L H      + PY         L RR+          G +   CP C   F    
Sbjct: 590 RPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVHQLVVHAGRQPHRCPSCGAAFPSSL 649

Query: 440 YLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIREKHRLWHAVR--EE 497
            LR+H     A               AP  F C  CG    +A   + H   HA     E
Sbjct: 650 RLREHRCAAAAAQ-------------APRRFECGTCGKKVGSAARLQAHEAAHAAAGPGE 696

Query: 498 LLL--PALAGAPPETSGP------------SGPSDGSAQQIFSCKHCPSTFFSSPGLTRH 543
           +L   P    AP  T  P            + P+  + ++   C  C   F +   L  H
Sbjct: 697 VLAKEPPAPRAPRATRAPVASPAALGSTATASPAAPARRRGLECSECKKLFSTETSLQVH 756

Query: 544 INKCHPSE 551
             + H  E
Sbjct: 757 -RRIHTGE 763



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 2/59 (3%)

Query: 257 RTPLGE--FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWH 313
           RT  GE  F C  C + +  P  LA+HR +      YRC +C K F+  + L  HR  H
Sbjct: 515 RTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLVH 573



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 62/273 (22%), Positives = 95/273 (34%), Gaps = 37/273 (13%)

Query: 290 EYRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASF 349
           +Y+C EC ++   P+ L  H+  H    A   A     +   PP SSS+   +     + 
Sbjct: 75  QYQCLECGQLLMSPSQLLEHQELHLKMMAPQEAVPAEPSPKAPPLSSSTIHYECVDCKAL 134

Query: 350 LAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHP---EPPLPQGPYT--- 403
            A  +      +T   H +A         P  AP     VL  P    PP+ Q       
Sbjct: 135 FASQELWLNHRQT---HLRAT--------PTKAPAP--VVLGSPVVLGPPVGQARVAVEH 181

Query: 404 ------EGVLGRRVPVPGSTSGGRGSEI----FVCPYCHKKFRRQAYLRKHLSTH-EAGS 452
                 EG  G  VP   +T+    +E+    + C  C + F+  A   +H +TH  A  
Sbjct: 182 SYRKAEEGGEGATVPSAAATTTEVVTEVELLLYKCSECSQLFQLPADFLEHQATHFPAPV 241

Query: 453 ARALAPGFGSERGAPLAFACPLCGAH-FPTADIREKHRLWHAVREELLLPALAGAPPETS 511
             +  P    E  A      P+      P +D   + R   A+  +              
Sbjct: 242 PESQEPALQQEVQASSPAEVPVSQPDPLPASDHSYELRNGEAIGRD------RRGRRARR 295

Query: 512 GPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHI 544
             SG + G+A Q   C  C   F S   L +H+
Sbjct: 296 NNSGEAGGAATQELFCSACDQLFLSPHQLQQHL 328


>gi|152963637 zinc finger protein 787 [Homo sapiens]
          Length = 382

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 49/195 (25%), Positives = 74/195 (37%), Gaps = 6/195 (3%)

Query: 263 FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANA 322
           + C  C   +    +LA+HR S      + CP C + FS P +LA H R H        A
Sbjct: 150 YTCPDCGRSFTQSKSLAKHRRSHSGLKPFVCPRCGRGFSQPKSLARHLRLHPELSGPGVA 209

Query: 323 ATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSA 382
           A V +A  +       +    G IA  + +G+    +    +    A   +GA     + 
Sbjct: 210 AKVLAASVRRAKGPEEAVAADGEIAIPVGDGEGIIVVGAPGEGAAAAAAMAGAGAKA-AG 268

Query: 383 PRQGLQVLTHPEPPLPQGP---YTEGVLGRRVPVPGSTSGGRGSE--IFVCPYCHKKFRR 437
           PR        P   L  G    +  G+L  +    G   G  G E    +C  C + F +
Sbjct: 269 PRSRRAPAPKPYVCLECGKGFGHGAGLLAHQRAQHGDGLGAAGGEEPAHICVECGEGFVQ 328

Query: 438 QAYLRKHLSTHEAGS 452
            A LR+H   H  G+
Sbjct: 329 GAALRRHKKIHAVGA 343



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 63/267 (23%), Positives = 90/267 (33%), Gaps = 40/267 (14%)

Query: 257 RTPLGEF--ICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHK 314
           RT  GE    C  C + ++    L QHR        Y C EC K FS  +NL  H+R H 
Sbjct: 86  RTHTGERPNACADCGKTFSQSSHLVQHRRIHTGEKPYACLECGKRFSWSSNLMQHQRIHT 145

Query: 315 -PRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFLAEG-----KENSRIERTADQHPQ 368
             +P        S    K   S +   R    +  F+         +   + R    HP+
Sbjct: 146 GEKPYTCPDCGRSFTQSK---SLAKHRRSHSGLKPFVCPRCGRGFSQPKSLARHLRLHPE 202

Query: 369 ARDSSGADQHPDSAPRQGL----QVLTHPEPPLPQGPYTEGVLGRRVPVPGSTS----GG 420
                 A +   ++ R+       V    E  +P G   EG++    P  G+ +     G
Sbjct: 203 LSGPGVAAKVLAASVRRAKGPEEAVAADGEIAIPVGD-GEGIIVVGAPGEGAAAAAAMAG 261

Query: 421 RGSEI-------------FVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAP 467
            G++              +VC  C K F   A L  H              G G+  G  
Sbjct: 262 AGAKAAGPRSRRAPAPKPYVCLECGKGFGHGAGLLAHQRAQH-------GDGLGAAGGEE 314

Query: 468 LAFACPLCGAHFPTADIREKHRLWHAV 494
            A  C  CG  F       +H+  HAV
Sbjct: 315 PAHICVECGEGFVQGAALRRHKKIHAV 341



 Score = 36.6 bits (83), Expect = 0.063
 Identities = 19/66 (28%), Positives = 29/66 (43%)

Query: 248 APSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLA 307
           AP  G      P   +IC  C + ++    L +H+ +        C +C K FS  ++L 
Sbjct: 51  APPAGPPPRPRPPAPYICNECGKSFSHWSKLTRHQRTHTGERPNACADCGKTFSQSSHLV 110

Query: 308 SHRRWH 313
            HRR H
Sbjct: 111 QHRRIH 116



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 64/267 (23%), Positives = 90/267 (33%), Gaps = 38/267 (14%)

Query: 291 YRCPECDKVFSCPANLASHRRWHKPRPAAANAATVSSADGKPPSSSSSSSRDSGAIASFL 350
           Y C EC K FS  + L  H+R H                G+ P++ +    D G   S  
Sbjct: 66  YICNECGKSFSHWSKLTRHQRTHT---------------GERPNACA----DCGKTFSQS 106

Query: 351 AEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRR 410
           +   ++ RI     + P A    G      S       ++ H      + PYT    GR 
Sbjct: 107 SHLVQHRRIH--TGEKPYACLECGKRFSWSS------NLMQHQRIHTGEKPYTCPDCGRS 158

Query: 411 VPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGS-----ARALAPGFG 461
                S +  R    G + FVCP C + F +   L +HL  H   S     A+ LA    
Sbjct: 159 FTQSKSLAKHRRSHSGLKPFVCPRCGRGFSQPKSLARHLRLHPELSGPGVAAKVLAASVR 218

Query: 462 SERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSA 521
             +G   A A        P  D      +           A+AGA  + +GP       A
Sbjct: 219 RAKGPEEAVAAD-GEIAIPVGDGEGIIVVGAPGEGAAAAAAMAGAGAKAAGPRS-RRAPA 276

Query: 522 QQIFSCKHCPSTFFSSPGLTRHINKCH 548
            + + C  C   F    GL  H    H
Sbjct: 277 PKPYVCLECGKGFGHGAGLLAHQRAQH 303



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 39/179 (21%), Positives = 62/179 (34%), Gaps = 14/179 (7%)

Query: 387 LQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLS 446
           + +L   +  +P  P T+    +  P  G     R    ++C  C K F   + L +H  
Sbjct: 27  VDILIMDDDDVPSWPPTKLSPPQSAPPAGPPPRPRPPAPYICNECGKSFSHWSKLTRHQR 86

Query: 447 THEAGSARALAP-GFGSERGAPLA-----------FACPLCGAHFPTADIREKHRLWHAV 494
           TH      A A  G    + + L            +AC  CG  F  +    +H+  H  
Sbjct: 87  THTGERPNACADCGKTFSQSSHLVQHRRIHTGEKPYACLECGKRFSWSSNLMQHQRIHTG 146

Query: 495 REELLLPALAGAPPET-SGPSGPSDGSAQQIFSCKHCPSTFFSSPGLTRHINKCHPSES 552
            +    P    +  ++ S        S  + F C  C   F     L RH+ + HP  S
Sbjct: 147 EKPYTCPDCGRSFTQSKSLAKHRRSHSGLKPFVCPRCGRGFSQPKSLARHL-RLHPELS 204


>gi|14249488 zinc finger and SCAN domain containing 10 [Homo
           sapiens]
          Length = 725

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 74/331 (22%), Positives = 115/331 (34%), Gaps = 72/331 (21%)

Query: 240 KIKEEEPGAPSRGLGGSRTPLGEFICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKV 299
           K +    G+ SR     R P   F+C  C + +     L  HR        + C  C + 
Sbjct: 447 KDRRSSEGSGSRRRDSDRRP---FVCSDCGKAFRRSEHLVAHRRVHTGERPFSCQACGRS 503

Query: 300 FSCPANLASHRRWH---KPRPA----------AANAATVSSADGKPPSSSSSSSRDSGAI 346
           F+  + L SH+R H   KP             A+ A  + +  G  P   +   +  G  
Sbjct: 504 FTQSSQLVSHQRVHTGEKPYACPQCGKRFVRRASLARHLLTHGGPRPHHCTQCGKSFG-- 561

Query: 347 ASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGV 406
                + ++ +R +R+       R S   +    SA      +  H      + P+    
Sbjct: 562 -----QTQDLARHQRSHTGEKPCRCSECGEGFSQSA-----HLARHQRIHTGEKPHACDT 611

Query: 407 LGRRVPVPGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLSTH-EAGSARALAPGFG 461
            G R     + +  R    G   + C  C + FRR A+LR+HL+TH E G  +A  P   
Sbjct: 612 CGHRFRNSSNLARHRRSHTGERPYSCQTCGRSFRRNAHLRRHLATHAEPGQEQAEPPQ-- 669

Query: 462 SERGAPLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSA 521
                     C  CG  F  +    +H L H            GA P             
Sbjct: 670 ---------ECVECGKSFSRSCNLLRHLLVH-----------TGARP------------- 696

Query: 522 QQIFSCKHCPSTFFSSPGLTRHINKCHPSES 552
              +SC  C  +F  +  L RH+ + H  E+
Sbjct: 697 ---YSCTQCGRSFSRNSHLLRHL-RTHARET 723



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 64/312 (20%), Positives = 106/312 (33%), Gaps = 55/312 (17%)

Query: 265 CQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRPAAANAAT 324
           C LC  ++     L++H  +      + C EC + F   A+L  H   H           
Sbjct: 351 CHLCGHRFRQSSHLSKHLLTHSSEPAFLCAECGRGFQRRASLVQHLLAH----------- 399

Query: 325 VSSADGKPPSSSSSSSRD---SGAIASFLAEG-KENSRIERTADQHPQARD-----SSGA 375
             + D KPP +  S +     +  + S   +  +  S ++R    H + +D      SG+
Sbjct: 400 --AQDQKPPCAPESKAEAPPLTDVLCSHCGQSFQRRSSLKRHLRIHARDKDRRSSEGSGS 457

Query: 376 -----DQHP------DSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPVPGSTSGGR--- 421
                D+ P        A R+   ++ H      + P++    GR           +   
Sbjct: 458 RRRDSDRRPFVCSDCGKAFRRSEHLVAHRRVHTGERPFSCQACGRSFTQSSQLVSHQRVH 517

Query: 422 -GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFP 480
            G + + CP C K+F R+A L +HL TH                G P    C  CG  F 
Sbjct: 518 TGEKPYACPQCGKRFVRRASLARHLLTH----------------GGPRPHHCTQCGKSFG 561

Query: 481 TADIREKHRLWHAVREELLLPALA-GAPPETSGPSGPSDGSAQQIFSCKHCPSTFFSSPG 539
                 +H+  H   +         G              + ++  +C  C   F +S  
Sbjct: 562 QTQDLARHQRSHTGEKPCRCSECGEGFSQSAHLARHQRIHTGEKPHACDTCGHRFRNSSN 621

Query: 540 LTRHINKCHPSE 551
           L RH  + H  E
Sbjct: 622 LARH-RRSHTGE 632



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 35/138 (25%), Positives = 47/138 (34%), Gaps = 37/138 (26%)

Query: 426 FVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGFGSERGAPLAFACPLCGAHFPTADIR 485
           F+C  C K F R + L+ H+ TH              ER      AC LCG  F  +   
Sbjct: 321 FLCLCCGKSFGRSSILKLHMRTHT------------DER----PHACHLCGHRFRQSSHL 364

Query: 486 EKHRLWH-------------------AVREELLLPALAGAPPETSGPSGPSDGSAQQIFS 526
            KH L H                   ++ + LL  A    PP    P   ++        
Sbjct: 365 SKHLLTHSSEPAFLCAECGRGFQRRASLVQHLLAHAQDQKPP--CAPESKAEAPPLTDVL 422

Query: 527 CKHCPSTFFSSPGLTRHI 544
           C HC  +F     L RH+
Sbjct: 423 CSHCGQSFQRRSSLKRHL 440


>gi|153945765 mitogen-activated protein kinase kinase kinase 1 [Homo
           sapiens]
          Length = 1512

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 58/190 (30%), Positives = 75/190 (39%), Gaps = 40/190 (21%)

Query: 41  APSASLPGAERATPPTREEPGKGLTAEAAREQSGSPCRAAGV--SPGTGGREGAEWRAG- 97
           A S+  PGA RAT P     G  L A +A      P  AAG+    G+GGRE A+WR   
Sbjct: 9   ASSSGFPGA-RATSPEAGGGGGALKASSA------PAAAAGLLREAGSGGRERADWRRRQ 61

Query: 98  -------------------GREGPGPSPSPSPSPAKPAGAELRRAFLERCLSSPVSAESF 138
                                  P  S SPSP PA  AG+     F    +  P  A S 
Sbjct: 62  LRKVRSVELDQLPEQPLFLAASPPASSTSPSPEPADAAGS--GTGFQPVAVPPPHGAASR 119

Query: 139 PGG--AAAVAAFSCSVAPAAAPTPGEQFLLPLRAPFPEPALQPDPAPLSAALQSLKRAAG 196
            G     +VAA     +  AA  PGE+     RAP  EP+  P  AP    +++ +   G
Sbjct: 120 GGAHLTESVAAPDSGASSPAAAEPGEK-----RAPAAEPS--PAAAPAGREMENKETLKG 172

Query: 197 GERRGKAPTD 206
             +    P +
Sbjct: 173 LHKMDDRPEE 182



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 8/91 (8%)

Query: 35  PPFLEEAPSASLPG-----AERATPPTREEPGKGLTAEAAREQSGSPCRAAGVSPGTGGR 89
           P FL  +P AS        A+ A   T  +P        A  + G+    +  +P +G  
Sbjct: 77  PLFLAASPPASSTSPSPEPADAAGSGTGFQPVAVPPPHGAASRGGAHLTESVAAPDSGAS 136

Query: 90  EGAEWRAGGREGPGPSPSPSPSPAKPAGAEL 120
             A    G +  P   PSP+   A PAG E+
Sbjct: 137 SPAAAEPGEKRAPAAEPSPA---AAPAGREM 164


>gi|45331217 zinc finger protein 526 [Homo sapiens]
          Length = 670

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 75/292 (25%), Positives = 95/292 (32%), Gaps = 32/292 (10%)

Query: 284 SRIVRVEYRCPECDKVFSCPANLASHRRWH--KPRPAAANAATVSSADGKPPSSSSSSSR 341
           S +    Y CPEC  + + P     H+  H         N       D +          
Sbjct: 190 SEVKMEPYECPECSTLCATPEEFLEHQGTHFDSLEKEERNGLEEEEEDDEEDEEDDEEME 249

Query: 342 DSGAIASFLAEGKENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGP 401
           D  A+A    +       E TA     A+      QH  SA  +     T   P     P
Sbjct: 250 DEEAMAEVGDDAVGGD--ESTAG---WAQGCGDCPQHQPSAGARRQHRRTAHSPASATHP 304

Query: 402 YTEGVLGR------RVPVPGSTSGGRGSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARA 455
           +      R      R+   G    G   E   C  C K F++ A L +HL  H  G AR 
Sbjct: 305 FHCSQCQRSFSSANRLQAHGRAHVGGTHE---CTTCSKVFKKAASLEQHLRLHR-GEARY 360

Query: 456 LAPGFGSERGAPLAF--------ACPL----CGAHFPTADIREKHRLWHAVREELLLPAL 503
           L    G   G  L          A PL    CG  F        HR  HA +     P  
Sbjct: 361 LCVDCGRGFGTELTLVAHRRAHTANPLHRCRCGKTFSNMTKFLYHRRTHAGKSG-APPTG 419

Query: 504 AGAPPETSGPSGPSDGSAQQI-FSCKHCPSTFFSSPGLTRHINKCH-PSESR 553
           A APP  + P+ P    A      C  C  +F S+  L+RH    H P E R
Sbjct: 420 ATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERR 471



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 74/367 (20%), Positives = 113/367 (30%), Gaps = 51/367 (13%)

Query: 206 DCASGPAAAGIKKPKAMRKLSFADEVTTSPVLGLKIKEEEPGAPSRGLGGSRTPLGEFIC 265
           DC     +AG ++    R+ + +    T P    + +     A      G     G   C
Sbjct: 277 DCPQHQPSAGARRQH--RRTAHSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGTHEC 334

Query: 266 QLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHKPRP-------- 317
             C + +    +L QH         Y C +C + F     L +HRR H   P        
Sbjct: 335 TTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCRCGK 394

Query: 318 --------------------AAANAATVSSADGK----PPSSSSSSSRDSGAIASFLAEG 353
                               A    AT   A  +    PP  +  +       +   A  
Sbjct: 395 TFSNMTKFLYHRRTHAGKSGAPPTGATAPPAPAEPTPPPPPPAPPAQLPCPQCSKSFASA 454

Query: 354 KENSRIERTADQHPQARDSSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPV 413
              SR  R     P+ R   G         ++ + V  H      + P+     G+    
Sbjct: 455 SRLSRHRRAVHGPPERRHRCGV---CGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFAS 511

Query: 414 PGSTSGGR----GSEIFVCPYCHKKFRRQAYLRKHLSTHEAGSARALAPGF---GSERGA 466
             + S  +    G+  + C  C K+F + + L++H   H    A A AP     G    +
Sbjct: 512 LANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHLRPVAFARAPRLPITGLYNKS 571

Query: 467 PLAFACPLCGAHFPTADIREKHRLWHAVREELLLPALAGAPPETSGPSGPSDGSAQQIFS 526
           P  + C  CG  F        H+  HA    L L      PP +  P+ P     QQ   
Sbjct: 572 P--YYCGTCGRWFRAMAGLRLHQRVHARARTLTL-----QPPRSPSPAPPPPPEPQQTIM 624

Query: 527 CKHCPST 533
           C     T
Sbjct: 625 CTELGET 631



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 43/162 (26%), Positives = 64/162 (39%), Gaps = 24/162 (14%)

Query: 257 RTPLGE--FICQLCKEQYADPFALAQHRCSRIVRVEYRCPECDKVFSCPANLASHRRWHK 314
           RT  GE  F C  C + +A    L++H+ +      Y+C +C K F+  +NL  HRR H 
Sbjct: 492 RTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRRLHL 551

Query: 315 PRPAA---ANAATVSSADGKPPSSSSSSSRDSGAIASFLAEGKENSRIERTADQHPQARD 371
            RP A   A    ++    K P    +  R   A+A      + ++R      Q P++  
Sbjct: 552 -RPVAFARAPRLPITGLYNKSPYYCGTCGRWFRAMAGLRLHQRVHARARTLTLQPPRS-- 608

Query: 372 SSGADQHPDSAPRQGLQVLTHPEPPLPQGPYTEGVLGRRVPV 413
                  P  AP         P PP PQ       LG  + +
Sbjct: 609 -------PSPAP---------PPPPEPQQTIMCTELGETIAI 634


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,064,913
Number of Sequences: 37866
Number of extensions: 1989089
Number of successful extensions: 37775
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1005
Number of HSP's successfully gapped in prelim test: 1144
Number of HSP's that attempted gapping in prelim test: 14185
Number of HSP's gapped (non-prelim): 19906
length of query: 566
length of database: 18,247,518
effective HSP length: 108
effective length of query: 458
effective length of database: 14,157,990
effective search space: 6484359420
effective search space used: 6484359420
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.