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Search of human proteins with 144922720
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|144922720 coiled-coil domain containing 15 [Homo sapiens]
(951 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|144922720 coiled-coil domain containing 15 [Homo sapiens] 1924 0.0
gi|148746195 trichohyalin [Homo sapiens] 79 3e-14
gi|71061468 centromere protein E [Homo sapiens] 56 1e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 53 2e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 8e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 50 1e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 50 1e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 50 1e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 50 1e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 50 1e-05
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 50 1e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 2e-05
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 4e-05
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 48 4e-05
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 48 4e-05
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 48 4e-05
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 5e-05
gi|34878777 ring finger protein 20 [Homo sapiens] 48 5e-05
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 47 6e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 47 1e-04
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 47 1e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 47 1e-04
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 46 1e-04
gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo sa... 46 1e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 45 2e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 45 3e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 45 3e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 45 4e-04
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 44 7e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 44 7e-04
>gi|144922720 coiled-coil domain containing 15 [Homo sapiens]
Length = 951
Score = 1924 bits (4985), Expect = 0.0
Identities = 951/951 (100%), Positives = 951/951 (100%)
Query: 1 MLGSMARKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVEPASPGSSEIPAYT 60
MLGSMARKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVEPASPGSSEIPAYT
Sbjct: 1 MLGSMARKKPRNTSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVEPASPGSSEIPAYT 60
Query: 61 SAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQS 120
SAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQS
Sbjct: 61 SAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQS 120
Query: 121 SATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQA 180
SATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQA
Sbjct: 121 SATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQA 180
Query: 181 RHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLA 240
RHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLA
Sbjct: 181 RHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLA 240
Query: 241 AVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQ 300
AVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQ
Sbjct: 241 AVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQ 300
Query: 301 KVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDT 360
KVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDT
Sbjct: 301 KVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDT 360
Query: 361 QAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALL 420
QAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALL
Sbjct: 361 QAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALL 420
Query: 421 TKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFL 480
TKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFL
Sbjct: 421 TKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFL 480
Query: 481 SRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFL 540
SRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFL
Sbjct: 481 SRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFL 540
Query: 541 SRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNIL 600
SRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNIL
Sbjct: 541 SRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNIL 600
Query: 601 PICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLAD 660
PICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLAD
Sbjct: 601 PICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLAD 660
Query: 661 YQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLP 720
YQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLP
Sbjct: 661 YQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLP 720
Query: 721 SSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRL 780
SSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRL
Sbjct: 721 SSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRL 780
Query: 781 FMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILA 840
FMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILA
Sbjct: 781 FMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILA 840
Query: 841 QLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTC 900
QLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTC
Sbjct: 841 QLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLYNITLPPLCCCGPDFWDAHPDTC 900
Query: 901 ANNCIFYKNHRAYTRALHSFINSCDVPGGNSTLRVAIHNFASAHRRTLKNL 951
ANNCIFYKNHRAYTRALHSFINSCDVPGGNSTLRVAIHNFASAHRRTLKNL
Sbjct: 901 ANNCIFYKNHRAYTRALHSFINSCDVPGGNSTLRVAIHNFASAHRRTLKNL 951
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 78.6 bits (192), Expect = 3e-14
Identities = 153/847 (18%), Positives = 354/847 (41%), Gaps = 91/847 (10%)
Query: 67 EELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSSATHLT 126
+EL+ Q RK++E + ++ ++ ++ R +++Q ++ E Q+E + +
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 127 SKRTSVFPNNLNVAIGSSRL---PPSLMPGDGIEDEENQNELFQQQAQAL----SETMKQ 179
+ + V +L P +E + + E QQ+ + L E +Q
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 180 ARHRLASFKTVIK--KKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRG-------EL 230
R R + ++ K+ + D+ ++S L + ++ A +G +L
Sbjct: 1194 ERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQL 1253
Query: 231 PIKVHQGLLAAVPYQNYM-ENQELDYEEP---------DYEESSSLVTDEKGKEDLFGR- 279
+ + Q+ + E QE D E+ + E L +E+ + R
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK 1313
Query: 280 GQQDQQAIHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEA 339
Q+++Q + E + K + KF+ +L E EEQ E +D ++ +
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE--RDRKFREEELRHQE 1371
Query: 340 QGDLLETQGDLTGIQSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIE 399
QG + Q + E +++ E E Q + + + E Q + + + +
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK 1431
Query: 400 LEEGSIVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDF--LPRDQHVL 457
E ++ Q+ + L + Q + + H +++ +L + ++Q RD+ L
Sbjct: 1432 FREEEQQVRRQE---RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFL 1488
Query: 458 HKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVL 517
++Q + + +D+ F ++ ++ L ++Q + + + + FL ++Q L R +
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ-LRRQERGQ 1547
Query: 518 PKDQNILPKYQGQDFL--PKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQN 575
+ Q+ K++ ++ L +++ LSR + +D+ F +Q V ++Q
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQE-------------RDRKFRLEEQKVRRQEQE 1594
Query: 576 ILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQ-DQDFLPK 634
+D+ L R +G Q +DR F + + ++ L + + D+ FL +
Sbjct: 1595 -RKFMEDEQQLRRQEGQQQLRQE-----RDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
Query: 635 YQKVHFKEPYSDMTDEKGR----EDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVRE 690
++ +E + ++ R E+ L + + + Q++D ++ R+ER R+
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Query: 691 ELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTE 750
L + +++ Q+ R+ + +L E+ ++ R +RY+ L E
Sbjct: 1709 FLQEEQ------QLRRQELERKFREEEQLRQETEQEQLRR---------QERYRKILEEE 1753
Query: 751 FQAPLAFQSDVDKEE-DKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKR 809
P + + ++E D+K R+++ LR R E +Q++ Q+ ++ +++ E+++++R
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQER-----EEQQLRSQESDRKFREE-EQLRQER 1807
Query: 810 EQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRA 869
E++ +QR + + E+ ++ + Q Q ++ R++Q R +E E R
Sbjct: 1808 EEQQLRPQQRDGKYRWEEE--------QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR 1859
Query: 870 QIQEKMQ 876
+ QE Q
Sbjct: 1860 EEQELWQ 1866
Score = 63.2 bits (152), Expect = 1e-09
Identities = 141/832 (16%), Positives = 353/832 (42%), Gaps = 93/832 (11%)
Query: 69 LKEQLRKKQ-------EALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSS 121
L+EQLRK+Q E L+ +++ + R Q+ + R+++QLQ+ E+ +E +
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQ 954
Query: 122 ATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQAR 181
++ +G P + + + EL Q++ Q L E ++ +
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEE--PEKRRRQEREKKYREEEELQQEEEQLLRE--EREK 1010
Query: 182 HRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLAA 241
R ++ +KK + ++ + L REE R+ EL
Sbjct: 1011 RRRQEWERQYRKKDELQQEEEQ---LLREEREKRRLQERERQYREEEEL----------- 1056
Query: 242 VPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSE-DKNKPFSRVQ 300
E ++L EE + L + +E+L Q+++Q + E +K + R +
Sbjct: 1057 -----QQEEEQLLGEERETRRRQELERQYRKEEEL---QQEEEQLLREEPEKRRRQERER 1108
Query: 301 KVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDT 360
+ + + L ++EE++ L E + E + + E + ++ + + L + K
Sbjct: 1109 QCREEEEL----QQEEEQLLREEREKRRRQELERQYREEE-EVQQEEEQLLREEPEKRRR 1163
Query: 361 QAVEMKV----QVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTN 416
Q +E + ++ + E Q + E + + E + + + ++ ++ + +D
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223
Query: 417 QALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKD 476
+ ++ ++D+ V K + Q +D RD+ Q +L + Q+++ +
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
Query: 477 QNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKD 536
+ + RD+H P+++ + + ++Q + ++ +L +++ + Q D ++
Sbjct: 1284 RRWQQRDRH-FPEEEQL--EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE 1340
Query: 537 QDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDF--LPRDQGYLP 594
++ L +++ P + Q++D R++ + ++Q + ++Q R++ +L
Sbjct: 1341 EEQLLQEREEQPL------RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLK 1394
Query: 595 KDQNILPICQDRD---FLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEK 651
++Q + CQ+R+ RD +Q + + +D+ F + Q+V +E
Sbjct: 1395 EEQQLR--CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE--------- 1443
Query: 652 GREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERV---REELPLDYHQYVVPKIQDQD 708
RE L +++ ++ ++ F EE++ REE L + ++++
Sbjct: 1444 -RERKFL----------EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 709 SPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEE--- 765
R Q + K F + E+ R P + Q + L + + ++E
Sbjct: 1493 QLRRQERDRK----FREQEL-RSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 766 -DKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMN 824
+++R +++ +L + E +Q+ Q+R ++ + + +K++++ ++ + +++ LR
Sbjct: 1548 QRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ 1607
Query: 825 FHEDPYSGEKLSEILAQLQLQEIKGTRE--KQQREKEYLRYVEALRAQIQEK 874
+ E+ + QL + + ++ +Q+R++++L LR Q +E+
Sbjct: 1608 EGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQ 1659
Score = 58.2 bits (139), Expect = 4e-08
Identities = 138/781 (17%), Positives = 326/781 (41%), Gaps = 99/781 (12%)
Query: 63 YLIEEELK---EQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERA-------QK 112
Y EEEL+ EQL ++++ + +++ +YR ++++ +K++Q + ++ +
Sbjct: 1170 YREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEP 1229
Query: 113 EGSIAMQSSATHLTSKRTSVFPNNLNVAIGSSRLPPSL--MPGDGIE-DEENQNELFQQQ 169
E A++ + + + F + + + L + G+ E D E + +QQ+
Sbjct: 1230 EKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQR 1289
Query: 170 AQALSETMKQARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGE 229
+ E + R K +K K L E R+ T +
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKSQE------EKQLLREEREEKRRRQETDRKFREEEQ 1343
Query: 230 LPIKVHQGLLAAVPYQNYMENQELDYEEPD---YEESSSLVTDEKGKEDLFGRGQQDQQA 286
L + + L +EL ++E EE L E+ ++ L +++Q
Sbjct: 1344 LLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFL-----KEEQQ 1398
Query: 287 IHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLET 346
+ +++ + + + KF+ L +E ++ E Q E + FLE + L +
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 347 QGDLTGIQSVKPDTQAV----EMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEE 402
+ + + + Q + E ++ E + + +E E Q ++ + + + Q + +E
Sbjct: 1459 RH-----RKFREEEQLLQEREEQQLHRQERDRKFLEEE-QQLRRQERDRKFREQELRSQE 1512
Query: 403 GSIVLKTQDFLPTNQAL-LTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKD- 460
+ FL Q L + Q L++ L + + + QD+D R++ L ++
Sbjct: 1513 PE-----RKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
Query: 461 --QDILPKYQDQNFLPKDQNFLSRDQH-VLPKDQDILPKYQDQNFLPKDQNFLSRDQHVL 517
Q + + +D+ F ++Q ++Q +D+ L + + Q L ++++ R+
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE---- 1623
Query: 518 PKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNIL 577
D+ +L + + Q ++ RD+ L ++ + + ++Q +++ +L
Sbjct: 1624 --DEQLLQEREEQQLHRQE-----RDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 578 PICQDQDFL--PRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFL--- 632
++Q RD+ + ++Q + ++R FL + + Q + K ++++ L
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL--RRQELERKFREEEQLRQE 1734
Query: 633 PKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREEL 692
+ +++ +E Y + +E+ L P+ ++Q + ++ F EE++R+E
Sbjct: 1735 TEQEQLRRQERYRKILEEEQ-----------LRPEREEQQLRRQERDRKFREEEQLRQER 1783
Query: 693 PLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQ 752
+++ Q+S R+ + +L E+ ++ G Y + L E Q
Sbjct: 1784 EEQ-------QLRSQESDRKFREEEQLRQEREEQQLRPQQRDG---KYRWEEEQLQLEEQ 1833
Query: 753 APLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQ--RQKEQKKKIEKIKKKRE 810
++ ++ER +QY R F E+ + +EQ+ +++EQK++ E+ +K RE
Sbjct: 1834 ----------EQRLRQERDRQY-RAEEQFATQEKSRREEQELWQEEEQKRRQERERKLRE 1882
Query: 811 Q 811
+
Sbjct: 1883 E 1883
Score = 57.8 bits (138), Expect = 5e-08
Identities = 154/846 (18%), Positives = 355/846 (41%), Gaps = 104/846 (12%)
Query: 66 EEELK--EQLRKKQEALKHFQKQVKYRVNQQIRL---------------------RKKQQ 102
E++L+ +QLR++QE +H QK + R Q+++ R+KQQ
Sbjct: 416 EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 103 LQKSYERAQKEGSIAMQSSATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEE-- 160
L++ E ++E + ++ +R RL E+EE
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ-------EEEERL 528
Query: 161 -----NQNELFQQQAQALSETMKQARH-RLASFKTVIKKKGSVFPDDGRKSFLTREEVLS 214
++ +L ++Q + + +K+ RL + + K ++ R L REE
Sbjct: 529 QQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKRE--QEERRDQLLKREEERR 586
Query: 215 RKPASTGINTGIRGELPIKVHQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKE 274
++ + L + + L Q Q L EEP+ E L+ E+ +E
Sbjct: 587 QQRLKREQEERLEQRLKREEVERL-----EQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 275 ---DLFGRGQQ---DQQAIHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDI 328
R QQ +Q+ E++ + R+++ + + EEEQ+Q E ++
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQAR-ERIKSR 700
Query: 329 LPEAQDYFLEAQGDLLETQGDLTGIQSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTET 388
+P+ Q + LE++ D +++ + S +P Q + + Q E + + E E Q + E
Sbjct: 701 IPKWQ-WQLESEADARQSK-----VYS-RPRKQEGQRRRQEQEEKRRRRESELQ-WQEEE 752
Query: 389 QGIMLKAQSIELEEGSIVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQD 448
+ + + + + + + ++ + L+ + + L ++ + ++Q
Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER---QQREQR 809
Query: 449 FLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQ-HVLPKDQDILPKYQDQNFLP--- 504
FLP ++ + + + ++ FL +++ R++ L +++D L + Q++
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869
Query: 505 KDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFL 563
+DQ + ++ + + K Q+ L K+Q L ++ L ++ + Q+Q+
Sbjct: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
Query: 564 PRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNIL 623
R++ L + +++ L ++ + + +D+ ++ +L +
Sbjct: 930 YREEEQLQQ--------EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE-- 979
Query: 624 PKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFM 683
K + Q+ KY++ +E ++ RE+ Q + + +D+++ Q+ +
Sbjct: 980 -KRRRQEREKKYRE---EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQ-QEEEQLL 1034
Query: 684 REERVREELPLDYHQYVVPKIQDQD------SPREQNKHIKLPSSFEKWEIARGNTPGVP 737
REER + L QY + Q+ RE + +L + K E +
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE--Q 1092
Query: 738 LAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKE 797
L + + E + + ++ +EE++ R+++ R R+ ++ER+ +E++ Q+E
Sbjct: 1093 LLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ---ELERQYREEEEVQQE 1149
Query: 798 QKKKI-EKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQR 856
+++ + E+ +K+R QE L + E+ ++ ++L + Q ++ + RE+Q R
Sbjct: 1150 EEQLLREEPEKRRRQE--------LERQYREEEELQQEEEQLLREEQ-EKRRQERERQYR 1200
Query: 857 EKEYLR 862
E+E L+
Sbjct: 1201 EEEELQ 1206
Score = 57.4 bits (137), Expect = 6e-08
Identities = 150/867 (17%), Positives = 367/867 (42%), Gaps = 84/867 (9%)
Query: 66 EEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKK---------QQLQKSYERAQKEGSI 116
EEE ++QL K +E + Q+Q++ ++ R K Q+L++ +E ++E +
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQEL 685
Query: 117 AM--QSSATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPG--DGIEDEENQNELFQQQAQA 172
A Q A R + L + + P +G + Q E +++
Sbjct: 686 AEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Query: 173 LSETMKQARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPI 232
L ++ HR + + + + KS R+ + +R P +R E
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAE-EKSERGRQRLSARPPLREQRERQLRAEERQ 804
Query: 233 KVHQGLLAAVPY--QNYMENQELDYEEPDYEESSSLVTDEKGK---EDLFGRGQQDQQAI 287
+ Q L Q + +E + E EE L E+ + E+ G Q+DQ+
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGL-QEDQERR 863
Query: 288 HSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQ 347
S+++ R QK +++ +EEE +++ H + P Q+ + Q L E +
Sbjct: 864 RSQEQR----RDQKWRWQ------LEEERKRRRHTLYAK---PALQEQLRKEQQLLQEEE 910
Query: 348 GDLTGIQSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVL 407
+L + K Q E + + E Q + E Q ++ E + + + + + +
Sbjct: 911 EELQREEREKRRRQEQERQYREEE---QLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 408 KTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKY 467
+ ++ L + + Q+ K +++ + Q+++ L R++ + Q+ +Y
Sbjct: 968 QKEEQLLGEEPEKRRRQEREKKYR----EEEEL---QQEEEQLLREEREKRRRQEWERQY 1020
Query: 468 QDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKY 527
+ ++ L +++ L R++ + Q+ +Y+++ L +++ L ++ + Q + +Y
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 528 QGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNIL---------- 577
+ ++ L ++++ L R++ + +C++++ L +++ L +++
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 578 ----PICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFLP 633
+ Q+++ L R++ + Q + ++ + L ++ L ++ + + +
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 634 KYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDD----IKNQQPASF--MREER 687
+ +++ ++ DE R D +Q P K D K ++ F + + +
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLK---WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Query: 688 VREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRY---Q 744
+R+ Q+++ + Q++D +E+ + + F + E DR +
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317
Query: 745 SGLSTEFQAPLAFQSDVDK---EEDK--KERQKQYLRHR---RLFMDIE-------REQV 789
L E + + + D+ EE++ +ER++Q LR + R F + E R+ +
Sbjct: 1318 KQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFL 1377
Query: 790 KEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKG 849
+E+QR + Q+++ + +K++++ C EQ++ + + ++LS + +E +
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 850 TREKQQREKEYLRYVEALRAQIQEKMQ 876
+Q+RE+++L + LR + K +
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFR 1464
Score = 57.0 bits (136), Expect = 8e-08
Identities = 147/866 (16%), Positives = 350/866 (40%), Gaps = 78/866 (9%)
Query: 66 EEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSSATH- 124
+EE +EQL K++E + Q++ + R+ ++ R+ Q L++ ER Q+ +
Sbjct: 542 QEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQR 601
Query: 125 LTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARHRL 184
L + R P + E Q E QQQ + + ++ R +
Sbjct: 602 LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKR 661
Query: 185 ASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGI-----RGELPIKVHQGLL 239
+ ++++ ++ R+ EE ++ A I + I + E Q +
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEE--EQEQARERIKSRIPKWQWQLESEADARQSKV 719
Query: 240 AAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHS-----EDKNK 294
+ P + + + + EE S L E E+ R QQ+++ + + K
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQE---EERAHRQQQEEEQRRDFTWQWQAEEK 776
Query: 295 PFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQD----ILPEAQDYFLEAQGDLLETQGDL 350
Q++ + PL E+ ++QL E Q LPE ++ + + E + +L
Sbjct: 777 SERGRQRLSARPPL----REQRERQLRAEERQQREQRFLPEEEEKE-QRRRQRREREKEL 831
Query: 351 TGIQSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQ 410
++ + Q E Q+ E E E + + E + +E EE T
Sbjct: 832 QFLEE-EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLE-EERKRRRHTL 889
Query: 411 DFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDIL------ 464
P Q L K Q +L ++ L +++ + Q+Q+ R++ L ++++ L
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 465 --PKYQDQNFLPKDQNFLSRDQHVLPKD------QDILPKYQDQNFLPKDQNFLSRDQHV 516
+ + + KD+ +++ +L ++ Q+ KY+++ L +++ L R++
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 517 LPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNI 576
+ Q +Y+ +D L ++++ L R++ + + ++++ L +++ L ++
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERE 1069
Query: 577 L--------------PICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNI 622
+ Q+++ L R++ + Q C++ + L ++ L ++
Sbjct: 1070 TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER- 1128
Query: 623 LPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASF 682
K + Q+ +Y++ +E ++ RE+ Q L + +++++++ Q+
Sbjct: 1129 -EKRRRQELERQYRE---EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ-QEEEQL 1183
Query: 683 MREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDR 742
+REE+ + + ++Q Q + + +WE + N Y +
Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCK 1243
Query: 743 YQSG-----------LSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKE 791
+ + Q L +E D+++ ++++ + R F + +E
Sbjct: 1244 GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE------EE 1297
Query: 792 QQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTR 851
Q ++EQK+ + +K +E++ E+R + E + ++L + + Q ++
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQE 1357
Query: 852 EKQQREKEYLRYVEALRAQIQEKMQL 877
++ +E LR+ E R ++E+ +L
Sbjct: 1358 RDRKFREEELRHQEQGRKFLEEEQRL 1383
Score = 56.6 bits (135), Expect = 1e-07
Identities = 148/849 (17%), Positives = 352/849 (41%), Gaps = 102/849 (12%)
Query: 64 LIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSSAT 123
L EEE +EQ ++++ L+ Q++ ++ RL+++++ ++ +R + E + +
Sbjct: 491 LEEEERREQQERREQQLRREQEE-----RREQRLKRQEEEERLQQRLRSEQQLRREQE-- 543
Query: 124 HLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARHR 183
+R + + R L E EE +++L +++ + + +K+ +
Sbjct: 544 ---ERREQLLKREEEKRLEQERREQRLKR----EQEERRDQLLKREEERRQQRLKREQEE 596
Query: 184 LASFKTVIKKKGSVFPDDGRKSFLTREE--------VLSRKPASTGINTGIRGELPIKVH 235
+ ++ + ++ R+ L REE +L + +R E +
Sbjct: 597 RLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Query: 236 QGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSE---DK 292
Q L + + + ++EE E+ + E+ +E + R + Q + SE +
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQ 716
Query: 293 NKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTG 352
+K +SR +K + + E+EE+++ LQ E + + Q + E + D T
Sbjct: 717 SKVYSRPRKQEGQRR---RQEQEEKRRRRESELQ--WQEEERAHRQQQEE--EQRRDFTW 769
Query: 353 IQSVKPDTQAVEMKVQVTEP-----EGQAIEPEGQP-----IKTETQGIMLKAQSIELEE 402
+ ++ ++ P E Q E Q + E + + Q E E+
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 403 GSIVLKTQDFLPTNQAL--LTKNQDVLLKDH-----CVLPKDQSILLKYQDQDFLPRDQH 455
L+ ++ L + L + +D L +D +DQ ++Q ++ R +H
Sbjct: 830 ELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK--WRWQLEEERKRRRH 887
Query: 456 VLHKDQDILPKY-QDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQ 514
L+ + + ++Q L +++ L R++ + Q+ +Y+++ L +++ L R++
Sbjct: 888 TLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREE 947
Query: 515 HVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQ 574
+ Q +Y+ L + ++ L ++ + K ++++ L +++ L +++
Sbjct: 948 REKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREE 1007
Query: 575 NILPICQD-------QDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNIL---- 623
Q+ +D L +++ L +++ Q+R+ R+ L ++ L
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067
Query: 624 -PKCQDQDFLPKYQKVH--FKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPA 680
+ Q+ +Y+K +E + +E + + QC + Q++ +Q
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE---EQLL 1124
Query: 681 SFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAY 740
RE+R R+EL Y + + +++ RE+ P + E+ R
Sbjct: 1125 REEREKRRRQELERQYREEEEVQQEEEQLLREE------PEKRRRQELER---------Q 1169
Query: 741 DRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKK 800
R + L E + L ++E+ ++ER++QY +++R++ K++ R ++Q+
Sbjct: 1170 YREEEELQQEEEQLLR----EEQEKRRQERERQYREEE----ELQRQKRKQRYRDEDQRS 1221
Query: 801 KI------EKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQ 854
+ EK R+ + Y + + ED +L + +Q LQ + G ++++
Sbjct: 1222 DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLED----SQLRDRQSQQDLQHLLGEQQER 1277
Query: 855 QREKEYLRY 863
RE+E R+
Sbjct: 1278 DREQERRRW 1286
Score = 49.7 bits (117), Expect = 1e-05
Identities = 153/842 (18%), Positives = 342/842 (40%), Gaps = 110/842 (13%)
Query: 67 EELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYE---RAQKEGSIAMQSSAT 123
+E +EQLRK + + +++ + QQ RLR++QQL++ E R Q+E Q
Sbjct: 272 QEEEEQLRKLER--QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 124 HLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARHR 183
+R R L E+E + +L ++Q + E + +
Sbjct: 330 QQEERREQQLRRE-----QEERREQQLRREQ--EEERREQQLRREQEEERREQQLRREQQ 382
Query: 184 LASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLAAVP 243
L + + R+ L RE+ L R+ +R E ++ Q L
Sbjct: 383 LRREQQL-----------RREQQLRREQQLRREQQ-------LRREQQLRREQQLRREQQ 424
Query: 244 YQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQKVK 303
+ E + + + L +++ + D R ++ ++ H +++ K + + +
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER--HEQERRKQQLKRDQEE 482
Query: 304 FKNPLFVLMEEE---EQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDT 360
+ ++ +EEE EQ++ + L+ E ++ L+ Q + Q L Q ++ +
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 361 QAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALL 420
+ E + Q+ + E E + ++ E + LK + E + +LK ++ Q L
Sbjct: 543 E--ERREQLLKRE------EEKRLEQERREQRLKREQEERRDQ--LLKREE--ERRQQRL 590
Query: 421 TKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFL 480
+ Q+ L+ + + + + + + L R++ + Q +L + + + Q L
Sbjct: 591 KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE---RRQQQL 647
Query: 481 SRDQHVLPKDQDILPKYQDQNF---LPKDQNFLSRDQHVLPKDQ--------NILPKYQG 529
R+Q ++Q + + +++ L ++ R+Q + ++Q + +PK+Q
Sbjct: 648 RREQQE-RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Query: 530 QDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRD 589
Q L + D +R V + P+ Q+ ++Q + + Q+++ R
Sbjct: 707 Q--LESEAD--ARQSKVYSR-----PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQ 757
Query: 590 QGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTD 649
Q +++ Q RDF + +++ Q++ + P + +
Sbjct: 758 Q----QEEE-----QRRDFTWQWQAEEKSERG-------------RQRLSARPPLREQRE 795
Query: 650 EKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDS 709
+ R + Q P+ ++++ + Q+ + + EE L + +++D
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG 855
Query: 710 PRE--QNKHIKLPSSFEKW----EIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDK 763
+E + + + +KW E R A Q L E Q + ++ +
Sbjct: 856 LQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQR 915
Query: 764 EEDKK----ERQKQYLRHRRLFMDIER--EQVKEQQRQKEQKKKIEKIKK--KREQECYA 815
EE +K E+++QY +L + E+ + +E++R++E++++ K KK ++E++
Sbjct: 916 EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 816 AEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKM 875
E R E Y E E L Q + Q ++ REK++R++ +Y + Q +E+
Sbjct: 976 EEPEKRRRQEREKKYREE---EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
Query: 876 QL 877
L
Sbjct: 1033 LL 1034
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/214 (22%), Positives = 101/214 (47%), Gaps = 26/214 (12%)
Query: 667 KSQDQDDIKNQQPASFMREERVREELP-----LDYHQYVVPKIQDQDSPREQNKHIKLPS 721
+ +++ + + ++ EE+++EE P L + + K++ Q+ RE+ + +
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 722 SFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLF 781
+ + R R Q E Q Q + + E ++ER++Q LR
Sbjct: 299 RLRREQQLR-----------RKQEEERREQQEERREQQE--RREQQEERREQQLRR---- 341
Query: 782 MDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQ 841
E+E+ +EQQ ++EQ+++ + + +REQE EQ++ R + ++ +
Sbjct: 342 ---EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRRE 398
Query: 842 LQL-QEIKGTREKQQREKEYLRYVEALRAQIQEK 874
QL +E + RE+Q R ++ LR + LR + +E+
Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Score = 39.7 bits (91), Expect = 0.014
Identities = 33/128 (25%), Positives = 67/128 (52%), Gaps = 9/128 (7%)
Query: 758 QSDVDKEEDKKERQKQYL---RHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECY 814
Q V +EE++KE +K+ + + E ++ +E Q ++EQ +K+E+ + +RE++
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 815 AAEQRILR----MNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQ--REKEYLRYVEALR 868
+Q+ LR + ++ E+ E Q + +E + R +QQ RE+E R + R
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 869 AQIQEKMQ 876
Q +E+ +
Sbjct: 354 EQEEERRE 361
Score = 38.1 bits (87), Expect = 0.039
Identities = 31/119 (26%), Positives = 68/119 (57%), Gaps = 14/119 (11%)
Query: 765 EDKKERQKQYLRHRRLFMDIERE--QVKEQQRQKEQ----KKKIEKIKKKREQECYAAEQ 818
E ++ ++ LR R L +++ R+ + K+QQR++ Q +++ EK +KRE E+
Sbjct: 200 ETEEFPDEEQLRRREL-LELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 819 RILRMNFHEDPYSGEKL---SEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEK 874
++ E+P +L E L +L+ QE++ R++++++++ LR + LR + +E+
Sbjct: 259 KLQ----EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE 313
Score = 32.7 bits (73), Expect = 1.7
Identities = 50/261 (19%), Positives = 102/261 (39%), Gaps = 49/261 (18%)
Query: 70 KEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQL-QKSYERAQKEGSIAMQSSATHLTSK 128
K Q ++++ A Q + + R+ Q+ R R+ ++L ++ E ++E A +
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199
Query: 129 RTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARHRLASFK 188
T FP+ E++ + EL + + + E +Q R R
Sbjct: 200 ETEEFPD---------------------EEQLRRRELLELRRKGREEKQQQRRER----- 233
Query: 189 TVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLAAVPYQNYM 248
+ VF ++ K + RE VL ++ ++ E P + + L +
Sbjct: 234 -----QDRVFQEEEEKEWRKRETVLRKEEEK------LQEEEPQRQRE-LQEEEEQLRKL 281
Query: 249 ENQELDYEEPDYEESSSLVT----------DEKGKEDLFGRGQQDQQAIHSEDKNKPFSR 298
E QEL E + E+ + +E+ ++ R QQ+++ E + + R
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 299 VQKVKFKNPLFVLMEEEEQKQ 319
Q+ + + L EEE ++Q
Sbjct: 342 EQEERREQQLRREQEEERREQ 362
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 56.2 bits (134), Expect = 1e-07
Identities = 162/870 (18%), Positives = 352/870 (40%), Gaps = 128/870 (14%)
Query: 69 LKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKS-YERAQKEGSIAMQSSATHLTS 127
LK +L K + L+ ++V+ R+N+ +L+++ + + S + ++E ++ + L
Sbjct: 864 LKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEE 923
Query: 128 KRT-SVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARHRLAS 186
+T + ++L S ++ + D I D N N Q+Q + E++KQ + + +
Sbjct: 924 VKTLTQEKDDLKQLQESLQIERDQLKSD-IHDTVNMNIDTQEQLRNALESLKQHQETINT 982
Query: 187 FKTVIKKKGS----------VFPDDGRKSF--LTREEVLSRKPASTGINTGIRGELPIKV 234
K+ I ++ S D+ ++ + +++ L K T + ++ I+
Sbjct: 983 LKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQT-LTADVKDNEIIEQ 1041
Query: 235 HQGLLAAVPYQNYMENQ------ELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIH 288
+ + + + +N ++ E + + D +E+ + + + + L G + QQ I
Sbjct: 1042 QRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIV 1101
Query: 289 SEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQG 348
+++KN + + + L E EE+ + + LQ E Q L Q ++ E Q
Sbjct: 1102 AQEKNHAIKK--EGELSRTCDRLAEVEEKLKEKSQQLQ----EKQQQLLNVQEEMSEMQK 1155
Query: 349 DLTGIQSVKPDTQAVEMKVQVTEPE----GQAIEPEGQPIKT---------------ETQ 389
+ I+++K + + E+ ++ E E Q + + +K+ ET+
Sbjct: 1156 KINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETE 1215
Query: 390 GIMLKAQSIELEEGSIVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQD- 448
L+ E+E + L+T++ L L ++Q+ + + + + + ++ QD +
Sbjct: 1216 RDHLRGYIREIE--ATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEK 1273
Query: 449 ---FLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLS-RDQHVLPKDQDILPKYQDQNFLP 504
L + VLH++Q++LP ++ + + N L + KD L + + + L
Sbjct: 1274 SHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMER-LR 1332
Query: 505 KDQNFLSRDQHV--LPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQD-QD 561
++ F + + L K+++ L + + DQ +H+ L K Q+ Q
Sbjct: 1333 LNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQ----LKEHIR----ETLAKIQESQS 1384
Query: 562 FLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQN 621
+ + KD I + + + PKD +L I + + L + +
Sbjct: 1385 KQEQSLNMKEKDNETTKIVSEM------EQFKPKDSALLRI--EIEMLGLSKRLQESHDE 1436
Query: 622 ILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPAS 681
+ +++D L + Q+V E SD E +E + + ++++K
Sbjct: 1437 MKSVAKEKDDLQRLQEVLQSE--SDQLKENIKE--------IVAKHLETEEELKVAHCCL 1486
Query: 682 FMREERVRE-ELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAY 740
+EE + E + L + + IQ Q K+ +EK E
Sbjct: 1487 KEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEE------------- 1533
Query: 741 DRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRR----LFMDIEREQVKEQQRQK 796
+F + + ++K KQ+ HR+ IE + ++ R +
Sbjct: 1534 ---------QFNI-----KQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQ 1579
Query: 797 EQKKKI-----EKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTR 851
E +++I EK + KR QE E+ L+ N E ++ E + Q ++
Sbjct: 1580 ESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQE--KEYQFLKMTAVN 1637
Query: 852 EKQQREKEYLRYVEALRAQIQ-EKMQLYNI 880
E Q++ E +E L+ Q + +K+ L NI
Sbjct: 1638 ETQEKMCE----IEHLKEQFETQKLNLENI 1663
Score = 34.3 bits (77), Expect = 0.57
Identities = 29/125 (23%), Positives = 63/125 (50%), Gaps = 9/125 (7%)
Query: 758 QSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQK-KKIEKIKKKREQECYAA 816
Q D+DK +D+ +++ Q L+ + +++ +VKE +K ++E++KK+ E + +
Sbjct: 1958 QKDLDKSKDELQKKIQELQKK----ELQLLRVKEDVNMSHKKINEMEQLKKQFEAQ-NLS 2012
Query: 817 EQRILRMNFHEDPYSGEKLSEI-LAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKM 875
Q + NF E L EI + + E++ +E + E++ +++ LR I
Sbjct: 2013 MQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERD--QFIATLREMIARDR 2070
Query: 876 QLYNI 880
Q + +
Sbjct: 2071 QNHQV 2075
Score = 33.5 bits (75), Expect = 0.97
Identities = 28/124 (22%), Positives = 61/124 (49%), Gaps = 10/124 (8%)
Query: 764 EEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRI--- 820
EE KE+ +Q ++ ++++ E + Q++ E + ++K K + +R+
Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELA 1185
Query: 821 --LRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLY 878
L N+ E+ S K ++L +LQ K ++ + Y+R +EA Q +E++++
Sbjct: 1186 QKLNENY-EEVKSITKERKVLKELQ----KSFETERDHLRGYIREIEATGLQTKEELKIA 1240
Query: 879 NITL 882
+I L
Sbjct: 1241 HIHL 1244
Score = 31.2 bits (69), Expect = 4.8
Identities = 89/461 (19%), Positives = 173/461 (37%), Gaps = 70/461 (15%)
Query: 66 EEELK---EQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSSA 122
+EELK L++ QE + + V + N+ ++K + +AQ + I +
Sbjct: 1720 QEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQ-DLKIQEELRI 1778
Query: 123 THLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQARH 182
H+ K + L + S M +D EN N Q++ Q L K H
Sbjct: 1779 AHMHLKEQQETIDKLRGIVSEKTDKLSNMQ----KDLENSNAKLQEKIQEL----KANEH 1830
Query: 183 RLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLLAAV 242
+L + K + + T+++V + I +++ LA
Sbjct: 1831 QLITLKKDVNE--------------TQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQK 1876
Query: 243 PYQNYMENQELDYEEPDY---EESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRV 299
++N E + + E + EE+ L D+ KE L +D + I E K +R+
Sbjct: 1877 LHENLEEMKSVMKERDNLRRVEETLKLERDQL-KESLQETKARDLE-IQQELKT---ARM 1931
Query: 300 QKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPD 359
+ K + L E+ +K + +Q L +++D E Q + E Q + VK D
Sbjct: 1932 LSKEHKETVDKLREKISEKTIQISDIQKDLDKSKD---ELQKKIQELQKKELQLLRVKED 1988
Query: 360 TQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQAL 419
K+ E + +K + + L QS+ ++
Sbjct: 1989 VNMSHKKIN-----------EMEQLKKQFEAQNLSMQSVRMDNFQ--------------- 2022
Query: 420 LTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNF 479
LTK L++ ++ K++ L + ++ + RDQ + + I Q+ P+ +
Sbjct: 2023 LTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLL 2082
Query: 480 LSRDQHV-------LPKDQDILPKYQDQNFLPKDQNFLSRD 513
QH+ + +++L +Y + + + N LS D
Sbjct: 2083 SDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSLD 2123
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 52.8 bits (125), Expect = 2e-06
Identities = 67/401 (16%), Positives = 172/401 (42%), Gaps = 72/401 (17%)
Query: 450 LPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNF 509
LP+++ VL +++I+P ++ LP+++ L ++ VLP+++++LP+
Sbjct: 10101 LPQEEEVLF-EEEIVP---EEEVLPEEEEVLPEEEEVLPEEEEVLPE------------- 10143
Query: 510 LSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGV 569
++ + P+++ + P+ ++++P++++F+ ++ VLP+ V
Sbjct: 10144 ---EEEIPPEEEEVPPE---EEYVPEEEEFVP-EEEVLPE-------------------V 10177
Query: 570 LPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQ 629
PK P+ + + + + +PK + P +P + + ILPK ++
Sbjct: 10178 KPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPA-----KVPEVPKKVEEKRIILPK--EE 10230
Query: 630 DFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVR 689
+ LP ++T+E E S + PP ++ +++ + +++
Sbjct: 10231 EVLP-----------VEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPE 10279
Query: 690 EELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLST 749
P+ P + P E K+P +K E P VP + +
Sbjct: 10280 APTPVPKKVEAPPAKVSKKIPEE-----KVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK 10334
Query: 750 EFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKR 809
+ P A V +E+ +++ + RL +++ +V+E ++E ++++
Sbjct: 10335 KEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEE----FHEVEEYF 10390
Query: 810 EQECYAAEQRILRMNFH--EDPYSGEKLSEILAQLQLQEIK 848
E+ + + +++ H E+ + EK+ ++ + +E++
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVE 10431
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/143 (17%), Positives = 79/143 (55%), Gaps = 16/143 (11%)
Query: 420 LTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQ----DQNFLPK 475
L + ++VL ++ ++P+++ + ++++ LP ++ VL +++++LP+ + ++ +P
Sbjct: 10101 LPQEEEVLFEEE-IVPEEEVLP---EEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPP 10156
Query: 476 DQNFLSRDQHVLPKDQ---DILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDF 532
++ ++ ++ +P+++ ++ PK +P+ + ++ + V+PK + P
Sbjct: 10157 EEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAK----- 10211
Query: 533 LPKDQDFLSRDQHVLPKDWNILP 555
+P+ + + +LPK+ +LP
Sbjct: 10212 VPEVPKKVEEKRIILPKEEEVLP 10234
Score = 35.0 bits (79), Expect = 0.33
Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 11/116 (9%)
Query: 769 ERQKQYLRHRRLFMDIEREQVKEQQRQKEQKK------KIEKIKKKREQECYAAEQRILR 822
ER Q + ++ + + +++ + R E+ K K+ K+K KRE+E A
Sbjct: 9638 ERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKV----- 9692
Query: 823 MNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLY 878
F + EK+S + + Q IK +++E+ Y EA+ Q +E+ + Y
Sbjct: 9693 TEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEY 9748
Score = 31.2 bits (69), Expect = 4.8
Identities = 15/60 (25%), Positives = 32/60 (53%)
Query: 759 SDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQ 818
+D KE++ K R K+ + ++ M + EQ++++ + K + K +EQE +E+
Sbjct: 483 ADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKEQETRISEE 542
Score = 31.2 bits (69), Expect = 4.8
Identities = 38/189 (20%), Positives = 73/189 (38%), Gaps = 18/189 (9%)
Query: 13 TSRLPLALNPLKSKDVLAVLAERNEAIVPVGAWVEPASPGSSEIPAYTSAYLIEEELKEQ 72
+S L + +K + V ++ I P + + EI + L EE+K
Sbjct: 32934 SSSCKLTIKAIKDTEAQKVSTQKTSEITP-----QKKAVVQEEI---SQKALRSEEIKMS 32985
Query: 73 LRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSSATHLTSKRTSV 132
K QE L ++ K ++++++ L+KS +E + Q+S T
Sbjct: 32986 EAKSQEKLALKEEASKVLISEEVKKSAATSLEKSI--VHEEITKTSQASEEVRTHAEIKA 33043
Query: 133 FPNNLNVAIGSSRLPPSLMPG--------DGIEDEENQNELFQQQAQALSETMKQARHRL 184
F +++ G + + + G +G+E ++ + + T+KQA HR
Sbjct: 33044 FSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRD 33103
Query: 185 ASFKTVIKK 193
T I K
Sbjct: 33104 EGILTCISK 33112
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 50.4 bits (119), Expect = 8e-06
Identities = 79/385 (20%), Positives = 166/385 (43%), Gaps = 80/385 (20%)
Query: 517 LPKDQNILPKYQGQ---DFLPKDQDFLSRDQHVLPKD---WNILPKCQDQDFLPRDQGVL 570
L + + +LP+ Q Q D L K+ +S ++ WN L + Q++ +++ +
Sbjct: 239 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 298
Query: 571 PKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQD 630
+++ I Q+Q+ R+Q + Q + + + + + R ++ + + + ++
Sbjct: 299 EREEKI----QEQEEKIREQEEKMRRQEEM-MWEKEEKMRRQEEMMWEKEEKIRELEE-- 351
Query: 631 FLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVRE 690
K+H +E + +++ E+ K ++Q+ + Q+ + +EE++RE
Sbjct: 352 ------KMHEQEKIREQEEKRQEEE-----------KIREQEKRQEQEAKMWRQEEKIRE 394
Query: 691 ELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTE 750
+ KI++Q+ ++ + + WE Q E
Sbjct: 395 Q---------EEKIREQEEMMQEQEEKMGEQEEKMWE----------------QEEEMQE 429
Query: 751 FQAPLAFQSDVDKEEDKKER-QKQYLRHRRLFMDIEREQVKEQQ---------------- 793
+ + Q + +E++KK R Q++ +R + M + E++ EQ+
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 794 -RQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPY-SGEKLSEILAQLQLQEIKGTR 851
R++E+K + E+ KK REQE EQ + E + EK+ E ++Q QE
Sbjct: 490 MRRQEEKIR-EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE----- 543
Query: 852 EKQQREKEYLRYVEALRAQIQEKMQ 876
EK +R++E +R E Q +EKMQ
Sbjct: 544 EKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 37.4 bits (85), Expect = 0.067
Identities = 71/357 (19%), Positives = 144/357 (40%), Gaps = 45/357 (12%)
Query: 64 LIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKE-GSIAMQSSA 122
+ +EELKE+ K QE L+ + + +I+L K+ L++ ERA+ +Q+ A
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESE-----KSEIQLNVKE-LKRKLERAKLLLPQQQLQAEA 255
Query: 123 THLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQAL---SETMKQ 179
HL + SV S++L +E+ E N L QQQ + + E +++
Sbjct: 256 DHLGKELQSV----------SAKLQAQ------VEENELWNRLNQQQEEKMWRQEEKIQE 299
Query: 180 ARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLL 239
++ + I+++ + E++ ++ IR EL K+H
Sbjct: 300 REEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR-ELEEKMH---- 354
Query: 240 AAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRV 299
E +++ +E +E + EK +E +Q+++ E+K + +
Sbjct: 355 ---------EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM 405
Query: 300 -----QKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQ 354
+K+ + EEE Q+Q Q+ Q+ + Q + + Q ++ Q
Sbjct: 406 MQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Query: 355 SVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQD 411
K Q +M Q + + Q + Q K Q ++ Q ++ E +++ Q+
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 522
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 50.1 bits (118), Expect = 1e-05
Identities = 147/869 (16%), Positives = 370/869 (42%), Gaps = 110/869 (12%)
Query: 65 IEEELKEQLRKKQEAL----KHFQKQVKY-RVNQQIRLRKKQQLQKSYERAQKEGSIAMQ 119
+EEE+ + +K++ + +H Q++ K+ R++++ +K++ Q+ + AQ+E +A +
Sbjct: 1546 LEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQE 1605
Query: 120 SSATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQALSETMKQ 179
++ + V I + G + EE + ++ +Q +E + Q
Sbjct: 1606 ERQLAQEERKLA----QAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQE-AEKLAQ 1660
Query: 180 ARHRLAS-FKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGL 238
R +LA ++ V +++ + G+ + + + +L++K ELP +
Sbjct: 1661 KRKKLAKKWEKVAREEEKLAKKGGKLAEV--KNILAQKVE----------ELPQREQN-- 1706
Query: 239 LAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSR 298
+ +Q QEL+ E D EE S +E +E+ G+ ++++ + E++ + R
Sbjct: 1707 ---LDWQEKELAQELEELEWDMEELS-WKEEELNQEE--GKLVEEKKKLAEEEEALAWQR 1760
Query: 299 V----QKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLT--- 351
++ K +L++E+E+ H E + PE ++ + L+E + L
Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKM----PEEEERLGRKREQLIEKKMKLAQKR 1816
Query: 352 -----GIQSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIV 406
++ + + + K + + E + + E + + + ++ + + + +V
Sbjct: 1817 ERWINSMEELTKNKMILYQKKNLAQ-EKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLV 1875
Query: 407 LKTQDFLPTNQAL------LTKNQDVLLKDHCVLPKDQSILLKYQD-----QDFLPRDQH 455
N+ L LT+ ++ ++K L + + L++ +D Q+ L +++
Sbjct: 1876 QVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKM 1935
Query: 456 VLHKDQDILP---KYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQN-FLS 511
L ++ ++ + + + + K++ L+ + L +++ L + + L K + S
Sbjct: 1936 KLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRL--VEGKETLSKGETPETS 1993
Query: 512 RDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLP 571
R + + +Q + + L ++ L + +L + + + K + + R Q +
Sbjct: 1994 RQRKMTQVEQELFERK-----LSLEEKILLHEDRILAMEESEIAKGKLE--FTRGQRIFV 2046
Query: 572 KDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDF 631
+ Q L + + + + + + I + L RD L+ ++ + K + F
Sbjct: 2047 QGQRKLAKAS-RKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALF 2105
Query: 632 LPKYQ------KVHFKE-PYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMR 684
+ + + K+ KE +S+ E +++ LA + Q + N+ +
Sbjct: 2106 VKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLA---------RKQRKLANKMRRMINK 2156
Query: 685 EERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKW----EIARGNTPGVPLA- 739
EE++ EE ++ + D++ + + + +P +W E RG+ P +
Sbjct: 2157 EEKMTEEESKLARKHSEVILDDEEEGGIEEEEV-IPFLKRRWRKRKEAKRGDKPKEKFSS 2215
Query: 740 ----------YDRYQSGLSTEFQAPLAFQSDVDKE-EDKKERQKQYLRHRRLFMDIEREQ 788
+ L E + + S+ ++E E+++ER+++ +R + ER++
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE----EEERKE 2271
Query: 789 VKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIK 848
+E + ++ +K++ EK KKK+E++ +++ E+ S E+ + + + +E
Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESC 2331
Query: 849 GTREKQQREKEYLRYVEALRAQIQEKMQL 877
E+ REKE L+ + + Q Q + L
Sbjct: 2332 SLEEEVDREKEILKKEKQFKLQEQRRKSL 2360
Score = 31.2 bits (69), Expect = 4.8
Identities = 35/181 (19%), Positives = 84/181 (46%), Gaps = 18/181 (9%)
Query: 703 KIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVD 762
K+ ++ +++K +K +E+W+ N +Y+ + + + +V
Sbjct: 1502 KLSPEEEMLQEDKKLK----WEEWKQVWENMLSSKSKEQQYKD------EEEVTLEEEVS 1551
Query: 763 KEEDKKERQ----KQYLRHRRLFMDIEREQVKEQQR--QKEQKKKIEKIKKKREQECYAA 816
+E ++KE+Q +++++ + I R++ + +++ Q+E+K E+ K +E+ A
Sbjct: 1552 REGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQ 1611
Query: 817 EQRILRMNFHEDPYSGEKLSEILAQL-QLQEIKGTR-EKQQREKEYLRYVEALRAQIQEK 874
E+R L + + ++++ + Q +E R EK +E E L A+ EK
Sbjct: 1612 EERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEK 1671
Query: 875 M 875
+
Sbjct: 1672 V 1672
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 9/215 (4%)
Query: 661 YQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLP 720
YQ + Q + QQ A+ +++ + L L Q + +I DQ+ + + +P
Sbjct: 621 YQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVP 680
Query: 721 SSFEKWEIA-RGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRR 779
+ WE+ + P V + L T P A + E+ K + +Q R
Sbjct: 681 DTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGP-ALEQLQQLEKAKAAKLEQERREAE 739
Query: 780 LFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEIL 839
+ E E+ K Q+ + Q+++I +++++E+E E+ L E+ ++ EI
Sbjct: 740 MRAKREEEERKRQEELRRQQEEI--LRRQQEEERKRREEEELARRKQEEALRRQREQEIA 797
Query: 840 AQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEK 874
+ Q +E E++Q+++E LR +E R + +E+
Sbjct: 798 LRRQREE-----EERQQQEEALRRLEERRREEEER 827
Score = 39.7 bits (91), Expect = 0.014
Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 28/147 (19%)
Query: 762 DKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQ---------------KEQKKKIEKIK 806
++EE + +Q++ LR +R R Q +E++RQ +E+++K E++
Sbjct: 775 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 834
Query: 807 KKREQEC--YAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTRE--KQQREKEYLR 862
+K+E+E +A E+ + E+ ++ E A+L+ +E + R+ + QR+KE +R
Sbjct: 835 RKQEEEAAKWAREEEEAQRRLEENRL---RMEEEAARLRHEEEERKRKELEVQRQKELMR 891
Query: 863 ----YVEALR--AQIQEKMQLYNITLP 883
EALR Q Q++ QL + LP
Sbjct: 892 QRQQQQEALRRLQQQQQQQQLAQMKLP 918
Score = 37.4 bits (85), Expect = 0.067
Identities = 29/129 (22%), Positives = 67/129 (51%), Gaps = 15/129 (11%)
Query: 758 QSDVDKEEDKKERQKQYLRHR---RLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECY 814
Q +++ + E + LRH R ++E ++ KE RQ++Q++ E +++ ++Q+
Sbjct: 852 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ--EALRRLQQQQ-- 907
Query: 815 AAEQRILRMNFHEDPYSGEKLSEILAQLQ-------LQEIKGTREKQQREKEYLRYVEAL 867
+Q++ +M G++ + Q Q +Q+++ RE+Q RE++ + E +
Sbjct: 908 -QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELM 966
Query: 868 RAQIQEKMQ 876
+A Q++ Q
Sbjct: 967 KALQQQQQQ 975
Score = 32.3 bits (72), Expect = 2.2
Identities = 31/137 (22%), Positives = 75/137 (54%), Gaps = 16/137 (11%)
Query: 670 DQDDIKNQQPASFMR---EERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKW 726
+++ ++ ++ A+ +R EER R+EL + + ++ + Q Q Q +L ++
Sbjct: 856 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ-----QEALRRLQQQQQQQ 910
Query: 727 EIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIER 786
++A+ P + + + + + QA L+ +++ K E+++ERQ + + R+ +R
Sbjct: 911 QLAQMKLPSSS-TWGQQSNTTACQSQATLSL-AEIQKLEEERERQLREEQRRQ-----QR 963
Query: 787 EQVKE-QQRQKEQKKKI 802
E +K QQ+Q++Q++K+
Sbjct: 964 ELMKALQQQQQQQQQKL 980
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 9/215 (4%)
Query: 661 YQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLP 720
YQ + Q + QQ A+ +++ + L L Q + +I DQ+ + + +P
Sbjct: 648 YQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVP 707
Query: 721 SSFEKWEIA-RGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRR 779
+ WE+ + P V + L T P A + E+ K + +Q R
Sbjct: 708 DTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGP-ALEQLQQLEKAKAAKLEQERREAE 766
Query: 780 LFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEIL 839
+ E E+ K Q+ + Q+++I +++++E+E E+ L E+ ++ EI
Sbjct: 767 MRAKREEEERKRQEELRRQQEEI--LRRQQEEERKRREEEELARRKQEEALRRQREQEIA 824
Query: 840 AQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEK 874
+ Q +E E++Q+++E LR +E R + +E+
Sbjct: 825 LRRQREE-----EERQQQEEALRRLEERRREEEER 854
Score = 39.7 bits (91), Expect = 0.014
Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 28/147 (19%)
Query: 762 DKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQ---------------KEQKKKIEKIK 806
++EE + +Q++ LR +R R Q +E++RQ +E+++K E++
Sbjct: 802 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 861
Query: 807 KKREQEC--YAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTRE--KQQREKEYLR 862
+K+E+E +A E+ + E+ ++ E A+L+ +E + R+ + QR+KE +R
Sbjct: 862 RKQEEEAAKWAREEEEAQRRLEENRL---RMEEEAARLRHEEEERKRKELEVQRQKELMR 918
Query: 863 ----YVEALR--AQIQEKMQLYNITLP 883
EALR Q Q++ QL + LP
Sbjct: 919 QRQQQQEALRRLQQQQQQQQLAQMKLP 945
Score = 37.4 bits (85), Expect = 0.067
Identities = 29/129 (22%), Positives = 67/129 (51%), Gaps = 15/129 (11%)
Query: 758 QSDVDKEEDKKERQKQYLRHR---RLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECY 814
Q +++ + E + LRH R ++E ++ KE RQ++Q++ E +++ ++Q+
Sbjct: 879 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ--EALRRLQQQQ-- 934
Query: 815 AAEQRILRMNFHEDPYSGEKLSEILAQLQ-------LQEIKGTREKQQREKEYLRYVEAL 867
+Q++ +M G++ + Q Q +Q+++ RE+Q RE++ + E +
Sbjct: 935 -QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELM 993
Query: 868 RAQIQEKMQ 876
+A Q++ Q
Sbjct: 994 KALQQQQQQ 1002
Score = 32.3 bits (72), Expect = 2.2
Identities = 31/137 (22%), Positives = 75/137 (54%), Gaps = 16/137 (11%)
Query: 670 DQDDIKNQQPASFMR---EERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKW 726
+++ ++ ++ A+ +R EER R+EL + + ++ + Q Q Q +L ++
Sbjct: 883 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ-----QEALRRLQQQQQQQ 937
Query: 727 EIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIER 786
++A+ P + + + + + QA L+ +++ K E+++ERQ + + R+ +R
Sbjct: 938 QLAQMKLPSSS-TWGQQSNTTACQSQATLSL-AEIQKLEEERERQLREEQRRQ-----QR 990
Query: 787 EQVKE-QQRQKEQKKKI 802
E +K QQ+Q++Q++K+
Sbjct: 991 ELMKALQQQQQQQQQKL 1007
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 9/215 (4%)
Query: 661 YQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLP 720
YQ + Q + QQ A+ +++ + L L Q + +I DQ+ + + +P
Sbjct: 627 YQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVP 686
Query: 721 SSFEKWEIA-RGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRR 779
+ WE+ + P V + L T P A + E+ K + +Q R
Sbjct: 687 DTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGP-ALEQLQQLEKAKAAKLEQERREAE 745
Query: 780 LFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEIL 839
+ E E+ K Q+ + Q+++I +++++E+E E+ L E+ ++ EI
Sbjct: 746 MRAKREEEERKRQEELRRQQEEI--LRRQQEEERKRREEEELARRKQEEALRRQREQEIA 803
Query: 840 AQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEK 874
+ Q +E E++Q+++E LR +E R + +E+
Sbjct: 804 LRRQREE-----EERQQQEEALRRLEERRREEEER 833
Score = 39.7 bits (91), Expect = 0.014
Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 28/147 (19%)
Query: 762 DKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQ---------------KEQKKKIEKIK 806
++EE + +Q++ LR +R R Q +E++RQ +E+++K E++
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 807 KKREQEC--YAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTRE--KQQREKEYLR 862
+K+E+E +A E+ + E+ ++ E A+L+ +E + R+ + QR+KE +R
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRL---RMEEEAARLRHEEEERKRKELEVQRQKELMR 897
Query: 863 ----YVEALR--AQIQEKMQLYNITLP 883
EALR Q Q++ QL + LP
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLP 924
Score = 37.4 bits (85), Expect = 0.067
Identities = 29/129 (22%), Positives = 67/129 (51%), Gaps = 15/129 (11%)
Query: 758 QSDVDKEEDKKERQKQYLRHR---RLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECY 814
Q +++ + E + LRH R ++E ++ KE RQ++Q++ E +++ ++Q+
Sbjct: 858 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ--EALRRLQQQQ-- 913
Query: 815 AAEQRILRMNFHEDPYSGEKLSEILAQLQ-------LQEIKGTREKQQREKEYLRYVEAL 867
+Q++ +M G++ + Q Q +Q+++ RE+Q RE++ + E +
Sbjct: 914 -QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELM 972
Query: 868 RAQIQEKMQ 876
+A Q++ Q
Sbjct: 973 KALQQQQQQ 981
Score = 32.3 bits (72), Expect = 2.2
Identities = 31/137 (22%), Positives = 75/137 (54%), Gaps = 16/137 (11%)
Query: 670 DQDDIKNQQPASFMR---EERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKW 726
+++ ++ ++ A+ +R EER R+EL + + ++ + Q Q Q +L ++
Sbjct: 862 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ-----QEALRRLQQQQQQQ 916
Query: 727 EIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIER 786
++A+ P + + + + + QA L+ +++ K E+++ERQ + + R+ +R
Sbjct: 917 QLAQMKLPSSS-TWGQQSNTTACQSQATLSL-AEIQKLEEERERQLREEQRRQ-----QR 969
Query: 787 EQVKE-QQRQKEQKKKI 802
E +K QQ+Q++Q++K+
Sbjct: 970 ELMKALQQQQQQQQQKL 986
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 49.7 bits (117), Expect = 1e-05
Identities = 48/215 (22%), Positives = 97/215 (45%), Gaps = 9/215 (4%)
Query: 661 YQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLP 720
YQ + Q + QQ A+ +++ + L L Q + +I DQ+ + + +P
Sbjct: 627 YQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVP 686
Query: 721 SSFEKWEIA-RGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRR 779
+ WE+ + P V + L T P A + E+ K + +Q R
Sbjct: 687 DTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGP-ALEQLQQLEKAKAAKLEQERREAE 745
Query: 780 LFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEIL 839
+ E E+ K Q+ + Q+++I +++++E+E E+ L E+ ++ EI
Sbjct: 746 MRAKREEEERKRQEELRRQQEEI--LRRQQEEERKRREEEELARRKQEEALRRQREQEIA 803
Query: 840 AQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEK 874
+ Q +E E++Q+++E LR +E R + +E+
Sbjct: 804 LRRQREE-----EERQQQEEALRRLEERRREEEER 833
Score = 39.7 bits (91), Expect = 0.014
Identities = 40/147 (27%), Positives = 76/147 (51%), Gaps = 28/147 (19%)
Query: 762 DKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQ---------------KEQKKKIEKIK 806
++EE + +Q++ LR +R R Q +E++RQ +E+++K E++
Sbjct: 781 EEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELL 840
Query: 807 KKREQEC--YAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTRE--KQQREKEYLR 862
+K+E+E +A E+ + E+ ++ E A+L+ +E + R+ + QR+KE +R
Sbjct: 841 RKQEEEAAKWAREEEEAQRRLEENRL---RMEEEAARLRHEEEERKRKELEVQRQKELMR 897
Query: 863 ----YVEALR--AQIQEKMQLYNITLP 883
EALR Q Q++ QL + LP
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLP 924
Score = 37.4 bits (85), Expect = 0.067
Identities = 29/129 (22%), Positives = 67/129 (51%), Gaps = 15/129 (11%)
Query: 758 QSDVDKEEDKKERQKQYLRHR---RLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECY 814
Q +++ + E + LRH R ++E ++ KE RQ++Q++ E +++ ++Q+
Sbjct: 858 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ--EALRRLQQQQ-- 913
Query: 815 AAEQRILRMNFHEDPYSGEKLSEILAQLQ-------LQEIKGTREKQQREKEYLRYVEAL 867
+Q++ +M G++ + Q Q +Q+++ RE+Q RE++ + E +
Sbjct: 914 -QQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELM 972
Query: 868 RAQIQEKMQ 876
+A Q++ Q
Sbjct: 973 KALQQQQQQ 981
Score = 32.3 bits (72), Expect = 2.2
Identities = 31/137 (22%), Positives = 75/137 (54%), Gaps = 16/137 (11%)
Query: 670 DQDDIKNQQPASFMR---EERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKW 726
+++ ++ ++ A+ +R EER R+EL + + ++ + Q Q Q +L ++
Sbjct: 862 EENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQ-----QEALRRLQQQQQQQ 916
Query: 727 EIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIER 786
++A+ P + + + + + QA L+ +++ K E+++ERQ + + R+ +R
Sbjct: 917 QLAQMKLPSSS-TWGQQSNTTACQSQATLSL-AEIQKLEEERERQLREEQRRQ-----QR 969
Query: 787 EQVKE-QQRQKEQKKKI 802
E +K QQ+Q++Q++K+
Sbjct: 970 ELMKALQQQQQQQQQKL 986
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 49.7 bits (117), Expect = 1e-05
Identities = 39/127 (30%), Positives = 72/127 (56%), Gaps = 11/127 (8%)
Query: 765 EDKKERQKQYLRHRRLFMDIEREQVKEQ-QRQKEQKKKIEKIKKKR--EQECYAAEQRIL 821
E +KE++++ +R + R+Q +EQ +R++E+K+++E+++++R E+E AE+
Sbjct: 400 EQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKR 459
Query: 822 RMNFHEDPYSGEKLS------EILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKM 875
R+ E Y +L E+L Q LQE E + RE E R E L+ Q+Q++
Sbjct: 460 RVE-REQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQE- 517
Query: 876 QLYNITL 882
Q Y ++L
Sbjct: 518 QAYLLSL 524
Score = 36.2 bits (82), Expect = 0.15
Identities = 46/198 (23%), Positives = 96/198 (48%), Gaps = 33/198 (16%)
Query: 684 REERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRY 743
R + R E ++Y + ++++ P ++ + PSS N PG
Sbjct: 308 RTRKKRGEKDETEYEYSGSEEEEEEVPEQEGE----PSSIV-------NVPG-------- 348
Query: 744 QSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIE--REQVKEQQRQKEQKKK 801
+S L +F L Q + +KE + R++Q L+ ++L E R+ + E+Q++ EQ+K+
Sbjct: 349 ESTLRRDF---LRLQQE-NKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKE 404
Query: 802 IEK---IKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREK 858
+ +++RE+E ++R R E+ +L E+ + + +E + E+++R
Sbjct: 405 QRRRLEEQQRREREARRQQEREQRRREQEEK---RRLEELERRRKEEEERRRAEEEKRRV 461
Query: 859 EYLRYVEALRAQIQEKMQ 876
E R E +R Q++E+ +
Sbjct: 462 E--REQEYIRRQLEEEQR 477
Score = 32.0 bits (71), Expect = 2.8
Identities = 15/49 (30%), Positives = 31/49 (63%)
Query: 64 LIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQK 112
L E++L+EQ K++ L QK+++ + Q+ RL ++Q+ ++ R Q+
Sbjct: 376 LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQE 424
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 48.9 bits (115), Expect = 2e-05
Identities = 101/560 (18%), Positives = 245/560 (43%), Gaps = 65/560 (11%)
Query: 354 QSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKT--ETQGIMLKAQSIELEEG-------S 404
+ +K ++ K+Q+ E E I+ + +K E ++L Q ++ E S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 405 IVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDIL 464
+ K Q + N+ NQ K K Q K Q+Q+ R+Q ++Q+
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 465 PKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNIL 524
+ Q++ K++ +++ + K++ + + Q++ K++ +++ + K++ I
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKM--RRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394
Query: 525 P---KYQGQDFLPKDQDFLSRDQHVLPKD---------WNILPKCQDQDFLPRDQGV--- 569
K Q+ + + ++ ++ + ++ W K ++Q+ R+Q
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 570 -----LPKDQNILPI--CQDQDFLPRDQGYLPKDQNILPIC-----QDRDFLPRDLHVLS 617
+ + + I Q+Q+ + R + + + + I Q+ ++ V
Sbjct: 455 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWR 514
Query: 618 NDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQ 677
++ I + Q++ + +K+ +E +E RE+ + + + K +++ + Q
Sbjct: 515 QEEKI--REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQE----KIWEEEKRQEQ 568
Query: 678 QPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVP 737
+ + +EE++RE+ + Q KI++Q+ R++ + +++ E R +
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQE--EKIREQEEKRQEQEE----KMWKQEEKIREQEEKIQ 622
Query: 738 LAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKE 797
++ + E + + Q ++ +E+++K +++ ++ E+ Q +E+ ++
Sbjct: 623 EQEEKIR-----EQEEKIREQEEMTQEQEEKMGEQE----EKMCEQEEKMQEQEETMWRQ 673
Query: 798 QKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGE-KLSEILAQLQLQEIKGTREKQQR 856
++K E+ KK REQE EQ + E + E K+ E ++Q QE K R++++
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 733
Query: 857 EKEYLRYVEALRAQIQEKMQ 876
++ +R LR Q +EKMQ
Sbjct: 734 WEQEVR----LRQQ-EEKMQ 748
Score = 35.4 bits (80), Expect = 0.25
Identities = 102/599 (17%), Positives = 262/599 (43%), Gaps = 61/599 (10%)
Query: 247 YMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQKVKFKN 306
Y+E + + E + +TDE+ KE + Q+ Q + SE K++ V+++K K
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKN-AKLQEKLQLVESE-KSEIQLNVKELKRKL 251
Query: 307 PLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDTQAVEMK 366
L+ ++Q Q + L L ++ L+AQ + E L Q K Q E K
Sbjct: 252 ERAKLLLPQQQLQAEADHLGKEL-QSVSAKLQAQVEENELWNRLNQQQEEKMWRQ--EEK 308
Query: 367 VQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALLTKNQDV 426
+Q E + I+ + + I+ + + I + + + +E + K + + + K + +
Sbjct: 309 IQEWE---EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 427 LLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHV 486
++ + K++ ++ Q++ +++ + +++ K +Q + + + ++ +
Sbjct: 366 RRQEEMMWEKEEK--MRRQEEMMWEKEEKI----RELEEKMHEQEKIREQEEKRQEEEKI 419
Query: 487 LPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHV 546
++ K Q+Q Q R+Q ++Q K Q+ +Q+ + ++
Sbjct: 420 REQE-----KRQEQEAKMWRQEEKIREQEEKIREQE--KKMWRQEEKIHEQEKIREEEKR 472
Query: 547 LPKD--WNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQ 604
++ W K +Q+ + R + + + + I + ++ + R + + + + I +
Sbjct: 473 QEQEEMWRQEEKIHEQEEIWRQKEKMHEQEE--KIRKQEEKVWRQEEKIREQEE--KIRE 528
Query: 605 DRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQ-- 662
+ + R + + + ++++ + + +K+ +E + D+ R++ + + +
Sbjct: 529 QEEKMWRQEEKIREQEEMW---REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585
Query: 663 --CLPPKSQDQDDIKNQQPASFMR-EERVREELPLDYHQYVVPKIQDQDSP-REQNKHIK 718
K ++Q++ + +Q + EE++RE+ KIQ+Q+ REQ + I+
Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQ---------EEKIQEQEEKIREQEEKIR 636
Query: 719 LPSSFEKWEIARGNTPGVPLAYDRY--QSGLSTEFQAPLAFQSDVDKEEDKKER-QKQYL 775
E+ E+ + + ++ Q E + + Q + +E++KK R Q++ +
Sbjct: 637 -----EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 776 RHRRLFMDIEREQVKEQQ--------RQKEQKKKIEKIKKKREQECYAAEQRILRMNFH 826
R + M + E++ EQ+ + +EQ++K+ + ++K ++ Q+ +M H
Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 48.1 bits (113), Expect = 4e-05
Identities = 114/660 (17%), Positives = 276/660 (41%), Gaps = 70/660 (10%)
Query: 244 YQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQKVK 303
Y+N + N+EL + + +E L EK + L + E K K +++ K
Sbjct: 214 YRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVK----------ELKRK----LERAK 259
Query: 304 FKNPLF---VLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDT 360
F P L EE +++ + + + ++ + L E +G + Q K
Sbjct: 260 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE-QEEKMWR 318
Query: 361 QAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALL 420
Q ++ Q E Q E Q + Q ++ Q ++ E ++ Q+ Q
Sbjct: 319 QEKRLREQEKELREQEKELREQK-ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 377
Query: 421 TKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQ--DILPKYQDQNFLPKDQN 478
Q+ +++ +DQ + QD+ +++ + +++ + + K +++ + ++Q
Sbjct: 378 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM-QEQE 436
Query: 479 FLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNIL---PKYQGQDFLPK 535
+RDQ ++++ + + +++ +++ +++ + +++N+ K Q LP+
Sbjct: 437 KKTRDQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Query: 536 DQDFL---SRDQHVLPKDWNILPKCQDQDFLPRDQGVL-----PKDQNILPICQDQDFLP 587
++ L + Q K W K +DQ+ + + + ++Q Q++
Sbjct: 496 QKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRD 555
Query: 588 RDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNIL----PKCQDQDFLPKYQKVHFKEP 643
++Q +++ + Q+++ D ++ + K ++++ + + Q+ +E
Sbjct: 556 QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 615
Query: 644 YSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPK 703
M +++ + Q K +Q++ +Q ++R+ E+ + K
Sbjct: 616 EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH---EK 672
Query: 704 IQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDK 763
+Q+Q+ +EQ + I EK + E + Q + +
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEK---------------------KTQEQEKKTWDQEKMRE 711
Query: 764 EEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKI-EKIKKKREQECYAAEQRIL- 821
EE +ER+K+ + + E + +++++ +EQ++++ E+ +K EQE EQ+ L
Sbjct: 712 EESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 822 ----RMNFHEDPYSGEKLSEILAQLQLQE--IKGTREKQQREKEYLRYVEALRAQIQEKM 875
++ HE EK+ E +++ QE ++G EK + ++E +R E +EKM
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Score = 35.4 bits (80), Expect = 0.25
Identities = 91/607 (14%), Positives = 262/607 (43%), Gaps = 43/607 (7%)
Query: 227 RGELPIKVHQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQA 286
R E ++ +G + + + + + L +E + E + ++K + + Q+ ++
Sbjct: 297 RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356
Query: 287 IHSEDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDI---LPEAQDYFLEAQGDL 343
+ +++ R Q+ K L E+E+Q + + ++D + E + E + +
Sbjct: 357 MWEQEEKM---REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 413
Query: 344 LETQGDLTGIQSVKPDTQAVEMKVQVTEPEGQAIEPEG---QPIKTETQGIMLKAQSIEL 400
E + ++ ++ + + E + + + E + E E + K + ++ Q ++
Sbjct: 414 REQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKM 473
Query: 401 EEGSIVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILL---KYQDQDFLPRDQHVL 457
++ + Q+ Q L + ++ L + + +++ I K +DQ+ + + +
Sbjct: 474 QKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKM 533
Query: 458 HKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVL 517
+ + + + Q+ +++ ++Q + +++ + K Q+Q DQ R++ +
Sbjct: 534 WRQEKM--REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERM 591
Query: 518 PKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKD-----WNILPKCQDQD--FLPRDQGVL 570
+ + K + ++ + ++Q+ ++Q ++ W K Q+Q+ +++ +
Sbjct: 592 REREK---KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648
Query: 571 PKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQD 630
+++ + +Q LP + L + + + Q+++ + + + + K Q+Q+
Sbjct: 649 EQEEKMW----EQQRLPEQKEKLWEHEKM----QEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 631 FLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDD-IKNQQPASFMREERVR 689
Q+ +E ++K RE+ + Q K Q+Q++ ++ Q+ + +EE++
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQ--EEKMQEQEEKMQEQEEEMWEQEEKMW 758
Query: 690 EELPLDYHQYVVP----KIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQS 745
E+ + Q +P K+ + + +EQ K + EK G +
Sbjct: 759 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEK---IWEQEEKMRDQEEKMRGQEEKMRGQEE 815
Query: 746 GLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKI 805
+ + + + + +E+K Q++ + + M+ + + +E+ R++E+K + ++
Sbjct: 816 KMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQE- 874
Query: 806 KKKREQE 812
+K REQE
Sbjct: 875 EKMREQE 881
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 48.1 bits (113), Expect = 4e-05
Identities = 88/410 (21%), Positives = 166/410 (40%), Gaps = 50/410 (12%)
Query: 445 QDQDFLPRDQ-HVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFL 503
Q+ D LP+ + H QD PK ++ PK+ + + + ++ LPK ++
Sbjct: 17 QEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQ 76
Query: 504 PKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDF 562
PK+ N S + + PK NI PK + PK+ D + + LPK ++
Sbjct: 77 PKESNIPKSSAKPIQPKLGNI-PKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAI 135
Query: 563 LPRDQGVLPKDQNILPICQDQDFLPRD--QGYLPKDQNILPICQDRDFLPRDLHVLSNDQ 620
P+ +G +PK + PI + + + PK+ +I P + P+ +
Sbjct: 136 QPK-EGDIPK-SSAKPIQPKLGNIAKTSVKPSQPKESDI-PKSPEETIQPK--------E 184
Query: 621 NILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGRE-DFSLADYQCLPPKSQDQDDIKNQQP 679
+PK + PK + P + + + +E D S + + + PK D P
Sbjct: 185 GDIPKSSAKPIQPKLGNI----PKASVKPSQPKEGDISKSPEEAIQPKEGD-------LP 233
Query: 680 ASFMREERVRE-ELPLDYHQYVVPKIQDQDSPRE---QNKHIKLPSSFEKW-EIARGNTP 734
S + +E ++P + + PK D E Q K +P S E+ + +G+ P
Sbjct: 234 KSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIP 293
Query: 735 GVPLAYDRYQSG--LSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKE- 791
P + + G + QA + D+ K ++ K+ +DI + +
Sbjct: 294 KSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKE--------IDIPKSPEETI 345
Query: 792 QQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQ 841
Q ++ + K +E+ +E + E+ M F E G+K+ IL++
Sbjct: 346 QPKEDDSPKSLEEATPSKEGDILKPEEE--TMEFPE----GDKVKVILSK 389
Score = 41.2 bits (95), Expect = 0.005
Identities = 62/299 (20%), Positives = 123/299 (41%), Gaps = 22/299 (7%)
Query: 434 LPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRD-QHVLPKDQD 492
+PK ++ + +D + + + +PK + PK N + PK+ D
Sbjct: 112 IPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESD 171
Query: 493 ILPKYQDQNFLPKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKD 550
I PK ++ PK+ + S + + PK NI PK + PK+ D S ++ + PK+
Sbjct: 172 I-PKSPEETIQPKEGDIPKSSAKPIQPKLGNI-PKASVKPSQPKEGDISKSPEEAIQPKE 229
Query: 551 WNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLP 610
+ LPK ++ P+ +G +PK ++ + +G +PK ++ D
Sbjct: 230 GD-LPKSLEEAIQPK-EGDIPK--------SPEEAIQPKEGDIPKSLEEAIQPKEGDIPK 279
Query: 611 RDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQD 670
+ + +PK ++ PK + K P + ++G D + + +PPK D
Sbjct: 280 SPEETIQPKKGDIPKSPEEAIQPKEGDIP-KSPKQAIQPKEG--DIPKSLEEAIPPKEID 336
Query: 671 --QDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWE 727
+ + QP + + E P + P+ + + P + +K+ S E +E
Sbjct: 337 IPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFP--EGDKVKVILSKEDFE 393
Score = 39.3 bits (90), Expect = 0.018
Identities = 43/218 (19%), Positives = 91/218 (41%), Gaps = 14/218 (6%)
Query: 373 EGQAIEPEGQPIKTETQGI-MLKAQSIELEEGSIVLKTQDFLPTNQALLTKN-QDVLLKD 430
EG + +PI+ + I + + +EG I ++ + + L K+ ++ +
Sbjct: 184 EGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPK 243
Query: 431 HCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNF-LSRDQHVLPK 489
+PK ++ ++ D + + + +PK ++ PK + S ++ + PK
Sbjct: 244 EGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPK 303
Query: 490 DQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLP- 548
+ DI PK Q PK+ + + +P + +PK + PK+ D + P
Sbjct: 304 EGDI-PKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPS 362
Query: 549 KDWNIL-PKCQDQDFLPRDQGVLPKDQNILPICQDQDF 585
K+ +IL P+ + +F P+ + I +DF
Sbjct: 363 KEGDILKPEEETMEF--------PEGDKVKVILSKEDF 392
Score = 38.1 bits (87), Expect = 0.039
Identities = 59/302 (19%), Positives = 118/302 (39%), Gaps = 22/302 (7%)
Query: 435 PKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDIL 494
PK ++ ++ D + + ++ LPK ++ PK+ N + +
Sbjct: 38 PKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNI 97
Query: 495 PKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKDWNI 553
PK + PK+ + + + + LPK + PK+ D S + + PK NI
Sbjct: 98 PKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI 157
Query: 554 L-----PKCQDQDFLPR--DQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDR 606
P + +P+ ++ + PK+ +I P + P+ G +PK ++
Sbjct: 158 AKTSVKPSQPKESDIPKSPEETIQPKEGDI-PKSSAKPIQPK-LGNIPKASVKPSQPKEG 215
Query: 607 DFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPP 666
D + + LPK ++ PK + K P + ++G D + + + P
Sbjct: 216 DISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQPKEG--DIPKSLEEAIQP 272
Query: 667 KSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQD-QDSPRE--QNKHIKLPSSF 723
K + DI + + + ++P + + PK D SP++ Q K +P S
Sbjct: 273 K---EGDIPKSPEETIQPK---KGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSL 326
Query: 724 EK 725
E+
Sbjct: 327 EE 328
Score = 35.4 bits (80), Expect = 0.25
Identities = 62/305 (20%), Positives = 119/305 (39%), Gaps = 26/305 (8%)
Query: 434 LPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDI 493
LPK ++ ++ + + +PK + PK+ + + + ++
Sbjct: 67 LPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKED 126
Query: 494 LPKYQDQNFLPKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKDW 551
LPK ++ PK+ + S + + PK NI K + PK+ D S ++ + PK+
Sbjct: 127 LPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI-AKTSVKPSQPKESDIPKSPEETIQPKEG 185
Query: 552 NILPKCQDQDFLPRDQGV--------LPKDQNILPICQDQDFLPRDQGYLPKDQNILPIC 603
+I PK + P+ + PK+ +I ++ + +G LPK
Sbjct: 186 DI-PKSSAKPIQPKLGNIPKASVKPSQPKEGDISK--SPEEAIQPKEGDLPKSLEEAIQP 242
Query: 604 QDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQC 663
++ D + + +PK ++ PK + K P + +KG D + +
Sbjct: 243 KEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIP-KSPEETIQPKKG--DIPKSPEEA 299
Query: 664 LPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPK-IQDQDSPRE--QNKHIKLP 720
+ PK + DI + +E ++P + + PK I SP E Q K P
Sbjct: 300 IQPK---EGDIPKSPKQAIQPKE---GDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSP 353
Query: 721 SSFEK 725
S E+
Sbjct: 354 KSLEE 358
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 48.1 bits (113), Expect = 4e-05
Identities = 88/410 (21%), Positives = 166/410 (40%), Gaps = 50/410 (12%)
Query: 445 QDQDFLPRDQ-HVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFL 503
Q+ D LP+ + H QD PK ++ PK+ + + + ++ LPK ++
Sbjct: 84 QEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQ 143
Query: 504 PKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDF 562
PK+ N S + + PK NI PK + PK+ D + + LPK ++
Sbjct: 144 PKESNIPKSSAKPIQPKLGNI-PKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAI 202
Query: 563 LPRDQGVLPKDQNILPICQDQDFLPRD--QGYLPKDQNILPICQDRDFLPRDLHVLSNDQ 620
P+ +G +PK + PI + + + PK+ +I P + P+ +
Sbjct: 203 QPK-EGDIPK-SSAKPIQPKLGNIAKTSVKPSQPKESDI-PKSPEETIQPK--------E 251
Query: 621 NILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGRE-DFSLADYQCLPPKSQDQDDIKNQQP 679
+PK + PK + P + + + +E D S + + + PK D P
Sbjct: 252 GDIPKSSAKPIQPKLGNI----PKASVKPSQPKEGDISKSPEEAIQPKEGD-------LP 300
Query: 680 ASFMREERVRE-ELPLDYHQYVVPKIQDQDSPRE---QNKHIKLPSSFEKW-EIARGNTP 734
S + +E ++P + + PK D E Q K +P S E+ + +G+ P
Sbjct: 301 KSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIP 360
Query: 735 GVPLAYDRYQSG--LSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKE- 791
P + + G + QA + D+ K ++ K+ +DI + +
Sbjct: 361 KSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKE--------IDIPKSPEETI 412
Query: 792 QQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQ 841
Q ++ + K +E+ +E + E+ M F E G+K+ IL++
Sbjct: 413 QPKEDDSPKSLEEATPSKEGDILKPEEE--TMEFPE----GDKVKVILSK 456
Score = 41.2 bits (95), Expect = 0.005
Identities = 62/299 (20%), Positives = 123/299 (41%), Gaps = 22/299 (7%)
Query: 434 LPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRD-QHVLPKDQD 492
+PK ++ + +D + + + +PK + PK N + PK+ D
Sbjct: 179 IPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESD 238
Query: 493 ILPKYQDQNFLPKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKD 550
I PK ++ PK+ + S + + PK NI PK + PK+ D S ++ + PK+
Sbjct: 239 I-PKSPEETIQPKEGDIPKSSAKPIQPKLGNI-PKASVKPSQPKEGDISKSPEEAIQPKE 296
Query: 551 WNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLP 610
+ LPK ++ P+ +G +PK ++ + +G +PK ++ D
Sbjct: 297 GD-LPKSLEEAIQPK-EGDIPK--------SPEEAIQPKEGDIPKSLEEAIQPKEGDIPK 346
Query: 611 RDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQD 670
+ + +PK ++ PK + K P + ++G D + + +PPK D
Sbjct: 347 SPEETIQPKKGDIPKSPEEAIQPKEGDIP-KSPKQAIQPKEG--DIPKSLEEAIPPKEID 403
Query: 671 --QDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWE 727
+ + QP + + E P + P+ + + P + +K+ S E +E
Sbjct: 404 IPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFP--EGDKVKVILSKEDFE 460
Score = 39.3 bits (90), Expect = 0.018
Identities = 43/218 (19%), Positives = 91/218 (41%), Gaps = 14/218 (6%)
Query: 373 EGQAIEPEGQPIKTETQGI-MLKAQSIELEEGSIVLKTQDFLPTNQALLTKN-QDVLLKD 430
EG + +PI+ + I + + +EG I ++ + + L K+ ++ +
Sbjct: 251 EGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPK 310
Query: 431 HCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNF-LSRDQHVLPK 489
+PK ++ ++ D + + + +PK ++ PK + S ++ + PK
Sbjct: 311 EGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPK 370
Query: 490 DQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLP- 548
+ DI PK Q PK+ + + +P + +PK + PK+ D + P
Sbjct: 371 EGDI-PKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPS 429
Query: 549 KDWNIL-PKCQDQDFLPRDQGVLPKDQNILPICQDQDF 585
K+ +IL P+ + +F P+ + I +DF
Sbjct: 430 KEGDILKPEEETMEF--------PEGDKVKVILSKEDF 459
Score = 38.1 bits (87), Expect = 0.039
Identities = 59/302 (19%), Positives = 118/302 (39%), Gaps = 22/302 (7%)
Query: 435 PKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDIL 494
PK ++ ++ D + + ++ LPK ++ PK+ N + +
Sbjct: 105 PKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNI 164
Query: 495 PKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKDWNI 553
PK + PK+ + + + + LPK + PK+ D S + + PK NI
Sbjct: 165 PKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI 224
Query: 554 L-----PKCQDQDFLPR--DQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDR 606
P + +P+ ++ + PK+ +I P + P+ G +PK ++
Sbjct: 225 AKTSVKPSQPKESDIPKSPEETIQPKEGDI-PKSSAKPIQPK-LGNIPKASVKPSQPKEG 282
Query: 607 DFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPP 666
D + + LPK ++ PK + K P + ++G D + + + P
Sbjct: 283 DISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQPKEG--DIPKSLEEAIQP 339
Query: 667 KSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQD-QDSPRE--QNKHIKLPSSF 723
K + DI + + + ++P + + PK D SP++ Q K +P S
Sbjct: 340 K---EGDIPKSPEETIQPK---KGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSL 393
Query: 724 EK 725
E+
Sbjct: 394 EE 395
Score = 35.4 bits (80), Expect = 0.25
Identities = 62/305 (20%), Positives = 119/305 (39%), Gaps = 26/305 (8%)
Query: 434 LPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDI 493
LPK ++ ++ + + +PK + PK+ + + + ++
Sbjct: 134 LPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKED 193
Query: 494 LPKYQDQNFLPKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKDW 551
LPK ++ PK+ + S + + PK NI K + PK+ D S ++ + PK+
Sbjct: 194 LPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI-AKTSVKPSQPKESDIPKSPEETIQPKEG 252
Query: 552 NILPKCQDQDFLPRDQGV--------LPKDQNILPICQDQDFLPRDQGYLPKDQNILPIC 603
+I PK + P+ + PK+ +I ++ + +G LPK
Sbjct: 253 DI-PKSSAKPIQPKLGNIPKASVKPSQPKEGDISK--SPEEAIQPKEGDLPKSLEEAIQP 309
Query: 604 QDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQC 663
++ D + + +PK ++ PK + K P + +KG D + +
Sbjct: 310 KEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIP-KSPEETIQPKKG--DIPKSPEEA 366
Query: 664 LPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPK-IQDQDSPRE--QNKHIKLP 720
+ PK + DI + +E ++P + + PK I SP E Q K P
Sbjct: 367 IQPK---EGDIPKSPKQAIQPKE---GDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSP 420
Query: 721 SSFEK 725
S E+
Sbjct: 421 KSLEE 425
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 48.1 bits (113), Expect = 4e-05
Identities = 88/410 (21%), Positives = 166/410 (40%), Gaps = 50/410 (12%)
Query: 445 QDQDFLPRDQ-HVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFL 503
Q+ D LP+ + H QD PK ++ PK+ + + + ++ LPK ++
Sbjct: 17 QEGDDLPKSSANTSHPKQDDSPKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQ 76
Query: 504 PKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDF 562
PK+ N S + + PK NI PK + PK+ D + + LPK ++
Sbjct: 77 PKESNIPKSSAKPIQPKLGNI-PKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAI 135
Query: 563 LPRDQGVLPKDQNILPICQDQDFLPRD--QGYLPKDQNILPICQDRDFLPRDLHVLSNDQ 620
P+ +G +PK + PI + + + PK+ +I P + P+ +
Sbjct: 136 QPK-EGDIPK-SSAKPIQPKLGNIAKTSVKPSQPKESDI-PKSPEETIQPK--------E 184
Query: 621 NILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGRE-DFSLADYQCLPPKSQDQDDIKNQQP 679
+PK + PK + P + + + +E D S + + + PK D P
Sbjct: 185 GDIPKSSAKPIQPKLGNI----PKASVKPSQPKEGDISKSPEEAIQPKEGD-------LP 233
Query: 680 ASFMREERVRE-ELPLDYHQYVVPKIQDQDSPRE---QNKHIKLPSSFEKW-EIARGNTP 734
S + +E ++P + + PK D E Q K +P S E+ + +G+ P
Sbjct: 234 KSLEEAIQPKEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIP 293
Query: 735 GVPLAYDRYQSG--LSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKE- 791
P + + G + QA + D+ K ++ K+ +DI + +
Sbjct: 294 KSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSLEEAIPPKE--------IDIPKSPEETI 345
Query: 792 QQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQ 841
Q ++ + K +E+ +E + E+ M F E G+K+ IL++
Sbjct: 346 QPKEDDSPKSLEEATPSKEGDILKPEEE--TMEFPE----GDKVKVILSK 389
Score = 41.2 bits (95), Expect = 0.005
Identities = 62/299 (20%), Positives = 123/299 (41%), Gaps = 22/299 (7%)
Query: 434 LPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRD-QHVLPKDQD 492
+PK ++ + +D + + + +PK + PK N + PK+ D
Sbjct: 112 IPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNIAKTSVKPSQPKESD 171
Query: 493 ILPKYQDQNFLPKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKD 550
I PK ++ PK+ + S + + PK NI PK + PK+ D S ++ + PK+
Sbjct: 172 I-PKSPEETIQPKEGDIPKSSAKPIQPKLGNI-PKASVKPSQPKEGDISKSPEEAIQPKE 229
Query: 551 WNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFLP 610
+ LPK ++ P+ +G +PK ++ + +G +PK ++ D
Sbjct: 230 GD-LPKSLEEAIQPK-EGDIPK--------SPEEAIQPKEGDIPKSLEEAIQPKEGDIPK 279
Query: 611 RDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQD 670
+ + +PK ++ PK + K P + ++G D + + +PPK D
Sbjct: 280 SPEETIQPKKGDIPKSPEEAIQPKEGDIP-KSPKQAIQPKEG--DIPKSLEEAIPPKEID 336
Query: 671 --QDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWE 727
+ + QP + + E P + P+ + + P + +K+ S E +E
Sbjct: 337 IPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFP--EGDKVKVILSKEDFE 393
Score = 39.3 bits (90), Expect = 0.018
Identities = 43/218 (19%), Positives = 91/218 (41%), Gaps = 14/218 (6%)
Query: 373 EGQAIEPEGQPIKTETQGI-MLKAQSIELEEGSIVLKTQDFLPTNQALLTKN-QDVLLKD 430
EG + +PI+ + I + + +EG I ++ + + L K+ ++ +
Sbjct: 184 EGDIPKSSAKPIQPKLGNIPKASVKPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPK 243
Query: 431 HCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNF-LSRDQHVLPK 489
+PK ++ ++ D + + + +PK ++ PK + S ++ + PK
Sbjct: 244 EGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIPKSPEETIQPKKGDIPKSPEEAIQPK 303
Query: 490 DQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLP- 548
+ DI PK Q PK+ + + +P + +PK + PK+ D + P
Sbjct: 304 EGDI-PKSPKQAIQPKEGDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPS 362
Query: 549 KDWNIL-PKCQDQDFLPRDQGVLPKDQNILPICQDQDF 585
K+ +IL P+ + +F P+ + I +DF
Sbjct: 363 KEGDILKPEEETMEF--------PEGDKVKVILSKEDF 392
Score = 38.1 bits (87), Expect = 0.039
Identities = 59/302 (19%), Positives = 118/302 (39%), Gaps = 22/302 (7%)
Query: 435 PKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDIL 494
PK ++ ++ D + + ++ LPK ++ PK+ N + +
Sbjct: 38 PKSSEETIQPKEGDIPKAPEETIQSKKEDLPKSSEKAIQPKESNIPKSSAKPIQPKLGNI 97
Query: 495 PKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKDWNI 553
PK + PK+ + + + + LPK + PK+ D S + + PK NI
Sbjct: 98 PKASVKPSQPKEGDIPKAPEETIQSKKEDLPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI 157
Query: 554 L-----PKCQDQDFLPR--DQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDR 606
P + +P+ ++ + PK+ +I P + P+ G +PK ++
Sbjct: 158 AKTSVKPSQPKESDIPKSPEETIQPKEGDI-PKSSAKPIQPK-LGNIPKASVKPSQPKEG 215
Query: 607 DFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPP 666
D + + LPK ++ PK + K P + ++G D + + + P
Sbjct: 216 DISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIP-KSPEEAIQPKEG--DIPKSLEEAIQP 272
Query: 667 KSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQD-QDSPRE--QNKHIKLPSSF 723
K + DI + + + ++P + + PK D SP++ Q K +P S
Sbjct: 273 K---EGDIPKSPEETIQPK---KGDIPKSPEEAIQPKEGDIPKSPKQAIQPKEGDIPKSL 326
Query: 724 EK 725
E+
Sbjct: 327 EE 328
Score = 35.4 bits (80), Expect = 0.25
Identities = 62/305 (20%), Positives = 119/305 (39%), Gaps = 26/305 (8%)
Query: 434 LPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQDI 493
LPK ++ ++ + + +PK + PK+ + + + ++
Sbjct: 67 LPKSSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPEETIQSKKED 126
Query: 494 LPKYQDQNFLPKDQNF-LSRDQHVLPKDQNILPKYQGQDFLPKDQDF-LSRDQHVLPKDW 551
LPK ++ PK+ + S + + PK NI K + PK+ D S ++ + PK+
Sbjct: 127 LPKSSEEAIQPKEGDIPKSSAKPIQPKLGNI-AKTSVKPSQPKESDIPKSPEETIQPKEG 185
Query: 552 NILPKCQDQDFLPRDQGV--------LPKDQNILPICQDQDFLPRDQGYLPKDQNILPIC 603
+I PK + P+ + PK+ +I ++ + +G LPK
Sbjct: 186 DI-PKSSAKPIQPKLGNIPKASVKPSQPKEGDISK--SPEEAIQPKEGDLPKSLEEAIQP 242
Query: 604 QDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQC 663
++ D + + +PK ++ PK + K P + +KG D + +
Sbjct: 243 KEGDIPKSPEEAIQPKEGDIPKSLEEAIQPKEGDIP-KSPEETIQPKKG--DIPKSPEEA 299
Query: 664 LPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPK-IQDQDSPRE--QNKHIKLP 720
+ PK + DI + +E ++P + + PK I SP E Q K P
Sbjct: 300 IQPK---EGDIPKSPKQAIQPKE---GDIPKSLEEAIPPKEIDIPKSPEETIQPKEDDSP 353
Query: 721 SSFEK 725
S E+
Sbjct: 354 KSLEE 358
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 47.8 bits (112), Expect = 5e-05
Identities = 56/255 (21%), Positives = 115/255 (45%), Gaps = 38/255 (14%)
Query: 636 QKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLD 695
+K+H +E + +++ E+ K ++Q+ + Q+ + +EE++RE+
Sbjct: 384 EKMHEQEKIREQEEKRQEEE-----------KIREQEKRQEQEAKMWRQEEKIREQEEKI 432
Query: 696 YHQ-----YVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTE 750
Q KI +Q+ RE+ K + + + E R + ++
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE-------EIWRQKEKMH 485
Query: 751 FQAPLAFQSD-VDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQ-KEQKKKI------ 802
Q + Q + V ++E+K Q++ +R + M + E+++EQ+ + +EQ++KI
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
Query: 803 --EKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEY 860
E+ +K EQE EQ +R + EK+ E Q ++I+ EK ++E
Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIRE-----QKEKIREQEEKIWEQEEK 600
Query: 861 LRYVEALRAQIQEKM 875
+R E + + +EKM
Sbjct: 601 IREQEEMMQEQEEKM 615
Score = 41.6 bits (96), Expect = 0.004
Identities = 42/214 (19%), Positives = 100/214 (46%), Gaps = 39/214 (18%)
Query: 669 QDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEI 728
+ ++ ++ + + +EE++RE L+ + KI++Q+ R++ + I+
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIR---------- 406
Query: 729 ARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQ 788
+ E +A + Q + +E+++K R+++ R+ E+E+
Sbjct: 407 ---------------EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 451
Query: 789 VKEQQRQKEQKKKIEKIKKKREQECY------AAEQRILRMNFHEDPYSGEKLSEILAQL 842
++E+++++EQ++ + +K REQE EQ +R + EK+ +
Sbjct: 452 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHD----- 506
Query: 843 QLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQ 876
Q ++I+ EK R++E +R E + +EK++
Sbjct: 507 QEEKIREQEEKMWRQEEKIREQEEKIREQEEKIR 540
Score = 39.7 bits (91), Expect = 0.014
Identities = 43/217 (19%), Positives = 97/217 (44%), Gaps = 22/217 (10%)
Query: 669 QDQDDIKNQQPASFMREERVREELPL---DYHQYVVPKIQDQDSPREQNKHIKLPSSFEK 725
+ ++ I+ Q+ + +EE++ E+ + + Q + ++ REQ + + +
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE 486
Query: 726 WEIARGNTPGVPLAYDRY---QSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFM 782
E R V ++ + + + + + + ++E+K Q++ +R + M
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546
Query: 783 DIEREQVKEQQ-RQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQ 841
+ E++ EQ+ + +EQ+K + +K REQE EQ+ EK+ E +
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK-------------EKIREQEEK 593
Query: 842 L--QLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQ 876
+ Q ++I+ E Q ++E + E + +EKMQ
Sbjct: 594 IWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 630
Score = 37.4 bits (85), Expect = 0.067
Identities = 29/123 (23%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 757 FQSDVDKEEDKKERQKQYLRHRRLFMDIEREQV--KEQQRQKEQKKKIEKIKKKREQECY 814
++ + ++E+K Q++ +R + M + E + KE++ +++++ EK +K R E
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEM 371
Query: 815 AAEQRILRMNFHEDPYSGEKLSEILAQLQLQE-IKGTREKQQREKEYLRYVEALRAQIQE 873
E+ E + EK+ E + Q +E I+ ++Q++E + R E +R Q +E
Sbjct: 372 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ-EE 430
Query: 874 KMQ 876
K++
Sbjct: 431 KIR 433
Score = 36.6 bits (83), Expect = 0.11
Identities = 33/135 (24%), Positives = 70/135 (51%), Gaps = 21/135 (15%)
Query: 758 QSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQ---------RQKEQKKKIEKIK-K 807
+ + ++E+K Q++ ++ + M + E+++EQ+ R++E+K + +K K +
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIR 588
Query: 808 KREQECYAAEQRILR----MNFHEDPY--SGEKLSEILAQLQLQEIKGTREKQQREKEYL 861
++E++ + E++I M E+ EK+ E ++Q QE EK +R++E +
Sbjct: 589 EQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE-----EKMRRQEEKM 643
Query: 862 RYVEALRAQIQEKMQ 876
E Q +EKMQ
Sbjct: 644 WEQEVRLRQQEEKMQ 658
Score = 35.8 bits (81), Expect = 0.20
Identities = 76/488 (15%), Positives = 197/488 (40%), Gaps = 55/488 (11%)
Query: 354 QSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKT--ETQGIMLKAQSIELEEG-------S 404
+ +K ++ K+Q+ E E I+ + +K E ++L Q ++ E S
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 405 IVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDIL 464
+ K Q + N+ NQ K K Q K Q+Q+ R+Q ++Q+
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 336
Query: 465 PKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNF--LSRDQHVLPKDQN 522
+ Q++ K++ +++ + K++ + + ++ K++ L H K +
Sbjct: 337 MRRQEEMMWEKEEKMRRQEEMMWEKEEKM--RRLEEMMWEKEEKIRELEEKMHEQEKIRE 394
Query: 523 ILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQD 582
K Q ++ + + + + Q K W K ++Q+ R+Q
Sbjct: 395 QEEKRQEEEKIREQE----KRQEQEAKMWRQEEKIREQEEKIREQ--------------- 435
Query: 583 QDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKE 642
+ + R + + + + I ++ + + ++ I + ++ + +K+H +E
Sbjct: 436 EKKMWRQEEKIHEQEKI----REEEKRQEQEEMWRQEEKIR---EQEEIWRQKEKMHEQE 488
Query: 643 PYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVP 702
++ R++ + D ++ I+ Q+ + +EE++RE+ Q
Sbjct: 489 KIRKQEEKVWRQEEKMHD---------QEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539
Query: 703 KIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDV- 761
+ Q++ ++ K + ++ E R + R Q E + + Q +
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKI-----REQEEKIREQKEKIREQEEKI 594
Query: 762 -DKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRI 820
++EE +E+++ + E + +++++ +EQ++K+ + ++K ++ Q+
Sbjct: 595 WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
Query: 821 LRMNFHED 828
+M H++
Sbjct: 655 EKMQEHQE 662
Score = 34.7 bits (78), Expect = 0.43
Identities = 29/118 (24%), Positives = 62/118 (52%), Gaps = 10/118 (8%)
Query: 763 KEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQ-KEQKKKI--------EKIKKKREQEC 813
++E+K RQ++ ++ + + E+++EQ+ + +EQ++K+ EK +K R QE
Sbjct: 297 QQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 356
Query: 814 YAAEQRILRMNFHEDPY-SGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQ 870
E+ E + EK+ E+ ++ QE +E++++E+E +R E + Q
Sbjct: 357 MMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 414
Score = 33.5 bits (75), Expect = 0.97
Identities = 78/467 (16%), Positives = 200/467 (42%), Gaps = 51/467 (10%)
Query: 64 LIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQ-KEGSIAMQSSA 122
+ +EELKE+ K QE L+ + + +I+L K +L++ ERA+ +Q+ A
Sbjct: 214 ITDEELKEKNAKLQEKLQLVESE-----KSEIQLNVK-ELKRKLERAKLLLPQQQLQAEA 267
Query: 123 THLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQAL---SETMKQ 179
HL + SV S++L +E+ E N L QQQ + + E +++
Sbjct: 268 DHLGKELQSV----------SAKLQAQ------VEENELWNRLNQQQEEKMWRQEEKIQE 311
Query: 180 ARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLL 239
++ + I+++ + K +EE++ K + E K+ + L
Sbjct: 312 WEEKIQEQEEKIREQEEKIREQEEK-MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR--L 368
Query: 240 AAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQ---QDQQAIHSEDKNKPF 296
+ ++ + +EL EE +E+ +EK +E+ R Q Q+Q+A + K
Sbjct: 369 EEMMWEKEEKIREL--EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 426
Query: 297 SRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSV 356
+ +K++ + EE+ +Q E +++ + + Q + + Q ++ +
Sbjct: 427 EQEEKIREQEKKMWRQEEKIHEQ---EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 357 KPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTN 416
+ + + + + + + + + + I+ + + + + + I +E I
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI---------RE 534
Query: 417 QALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKD 476
Q + Q+ ++++ +Q K Q+Q+ + R + + + ++ K ++Q ++
Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQE--EKMQEQEKMRRQEEKIREQEE---KIREQKEKIRE 589
Query: 477 QNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNI 523
Q +Q ++Q+ + + Q++ +++ +++ + +++ +
Sbjct: 590 QEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 47.8 bits (112), Expect = 5e-05
Identities = 36/131 (27%), Positives = 76/131 (58%), Gaps = 10/131 (7%)
Query: 747 LSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIK 806
LS++ A A Q D ++ + K++ +++ R + ERE+ KE++R++E K+K+++ +
Sbjct: 543 LSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKEKERERE-KQKLKESE 601
Query: 807 KKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEA 866
K+R+ +A+ + H+D +K +EI+ QL++ E+K +E Q+ K L +
Sbjct: 602 KERD----SAKDK--EKGKHDD--GRKKEAEIIKQLKI-ELKKAQESQKEMKLLLDMYRS 652
Query: 867 LRAQIQEKMQL 877
+ ++K+QL
Sbjct: 653 APKEQRDKVQL 663
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 47.4 bits (111), Expect = 6e-05
Identities = 51/268 (19%), Positives = 123/268 (45%), Gaps = 25/268 (9%)
Query: 615 VLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDI 674
+ D N + +D+ L + F++ + + +EKG+++ + + + + + +
Sbjct: 259 ITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERER 318
Query: 675 KNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTP 734
+ ++ ER RE + + +D+D +E+++ ++
Sbjct: 319 ERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR--------- 369
Query: 735 GVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQR 794
DR +S + ++ +S + E ++ER+++ R R + ERE+ +E++R
Sbjct: 370 ------DRERSSDRNKDRSRSREKSRDRERERERERERERERER----ERERERERERER 419
Query: 795 QKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTRE-- 852
++E++++ +K + + E E A E+R L E + E L +++E K TRE
Sbjct: 420 EREREREKDKKRDREEDEEDAYERRKLERKLREKEAA---YQERLKNWEIRERKKTREYE 476
Query: 853 -KQQREKEYLRYVEALRAQIQEKMQLYN 879
+ +RE+E R + +++E ++ Y+
Sbjct: 477 KEAEREEERRREMAKEAKRLKEFLEDYD 504
Score = 39.3 bits (90), Expect = 0.018
Identities = 37/197 (18%), Positives = 87/197 (44%), Gaps = 22/197 (11%)
Query: 666 PKSQDQDDIKNQQPASFMREERVR---EELPLDYHQYVVPKIQDQDSPREQNKHIKLPSS 722
P++ DD + + R++ ++ E L +Y + Q+ DS + K K
Sbjct: 185 PETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDI 244
Query: 723 FEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFM 782
F ++ +A P +P PL + D++ E +++++ R F
Sbjct: 245 FRRFPVA----PLIPY---------------PLITKEDINAIEMEEDKRDLISREISKFR 285
Query: 783 DIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQL 842
D ++ +E+ ++++++++IEK +++RE+E +R R E EK E +
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Query: 843 QLQEIKGTREKQQREKE 859
+ + +++ R+++
Sbjct: 346 ERDRDRDRTKERDRDRD 362
Score = 35.4 bits (80), Expect = 0.25
Identities = 41/221 (18%), Positives = 103/221 (46%), Gaps = 16/221 (7%)
Query: 667 KSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKW 726
KS+D++ + ++ ER RE + + +++D R++ + + ++E+
Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEE--DAYERR 444
Query: 727 EIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFM---D 783
++ R +R ++ E + ++ + ++EE+++ + + + F+ D
Sbjct: 445 KLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYD 504
Query: 784 IEREQVKE------QQRQKEQKKKIE---KIKKKREQECYAAEQRILRMNFHEDPYSGEK 834
+R+ K Q+R ++++K++E + +K+ ++E QR+L H DP + +
Sbjct: 505 DDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEG-HPDPDAELQ 563
Query: 835 LSEILAQLQLQ-EIKGTREKQQREKEYLRYVEALRAQIQEK 874
E A+ + Q +IK E ++ E+E E ++E+
Sbjct: 564 RMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 46.6 bits (109), Expect = 1e-04
Identities = 106/534 (19%), Positives = 235/534 (44%), Gaps = 60/534 (11%)
Query: 357 KPDTQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTN 416
K + + + ++ E EG+ E E + + E + L+ Q EL E L+ Q L
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKR---LREQEKELREQEKELREQKKLREQ 308
Query: 417 QALLTKNQDVLLKDHCVLPKDQSILLKYQD----QDFLPRDQHVLHKDQDILPKYQDQNF 472
+ + + ++ + + + + + + + ++ Q+ R+Q +DQ+ QD+
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 473 LPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDF 532
K++ R+Q + + ++ K Q++ + + + + ++ + + + K Q Q+
Sbjct: 369 REKEERM--REQEKMWEQEE---KMQEEERIREREKKMREEEETMREQEE---KMQKQEE 420
Query: 533 LPKDQDFLSRDQHVLPKDWNIL---PKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRD 589
+Q+ Q LP+ L K Q+Q+ +Q +DQ + Q++ ++
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEM-WGQEKKMWRQE 479
Query: 590 QGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTD 649
+ +DQ +++ RD DQ QD+ K +++ ++ +
Sbjct: 480 KMREQEDQ-----MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ-E 533
Query: 650 EKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDS 709
EK RE+ + + K+ DQ++ ++ RE+++REE + Q K+Q+Q+
Sbjct: 534 EKMREEKKTQEQE---KKTWDQEEKMREEERMREREKKMREEEEMMREQE--EKMQEQEE 588
Query: 710 P-REQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKK 768
REQ + K+ EK + Q E + + Q + DK ++++
Sbjct: 589 KMREQEE--KMWEQEEKMQ---------------EQEEKMWEQEEKMWEQEEEDKMQEQE 631
Query: 769 E---RQKQYLRHRRLFMDIEREQVKEQQ---RQKEQKKKIEKIKKKREQECYAAEQRILR 822
E Q++ ++ + M + E+++EQ+ R++E+K + ++ K + ++E ++ +R
Sbjct: 632 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMR 691
Query: 823 MNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQ 876
+ EK+ ++ QE K +++ REKE E +R Q +EKMQ
Sbjct: 692 EQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKE-----ERIRDQ-KEKMQ 739
Score = 43.1 bits (100), Expect = 0.001
Identities = 85/457 (18%), Positives = 211/457 (46%), Gaps = 50/457 (10%)
Query: 433 VLPKDQSILLK---YQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNFLSRDQHVLPK 489
+LP+ Q+ L+ ++ ++ L + + K ++ + + +++ ++Q R+Q +
Sbjct: 223 LLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERL---REQEGKMREQEEKMR 279
Query: 490 DQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNILPKYQGQDFLPKDQDFLSRDQHVLPK 549
Q+ + Q++ +++ R+Q L + + + Q Q+ +Q+ R+Q K
Sbjct: 280 RQEKRLREQEKELREQEKEL--REQKKLREQEE---QMQEQEEKMWEQEEKMREQE--EK 332
Query: 550 DWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQGYLPKDQNILPICQDRDFL 609
W + +Q+ R+Q +DQ QD+ +++ +++ + + + +
Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK----MWEQEEKM 388
Query: 610 PRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQ 669
+ + ++ K ++++ + Q+ ++ +M +++ +E Q LP + +
Sbjct: 389 QEEERIREREK----KMREEEETMREQEEKMQKQEENMWEQEEKE----WQQQRLPEQKE 440
Query: 670 ---DQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKW 726
+Q+ ++ Q+ + +EE++R++ + + K+ Q+ REQ + +E+
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE---KKMWRQEKMREQEDQM-----WEQE 492
Query: 727 EIARGNTPGVPLAYDRY--QSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDI 784
E R + +R Q E + + Q + ++E+K +K+ + D
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD- 551
Query: 785 EREQVKEQQRQKEQKKKI-EKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQ 843
+ E+++E++R +E++KK+ E+ + REQE EQ +M E EK+ E ++Q
Sbjct: 552 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQE-EKMREQE-----EKMWEQEEKMQ 605
Query: 844 LQEIKGTREK----QQREKEYLRYVEALRAQIQEKMQ 876
QE K ++ +Q E++ ++ E + + +EKMQ
Sbjct: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
Score = 35.4 bits (80), Expect = 0.25
Identities = 31/114 (27%), Positives = 61/114 (53%), Gaps = 6/114 (5%)
Query: 763 KEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILR 822
KE +K + ++L + ++ E ++++ +EQ+KKI +K+E++ + E+R LR
Sbjct: 211 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI----RKQEEKMWRQEER-LR 265
Query: 823 MNFHEDPYSGEKLSEILAQLQLQEIK-GTREKQQREKEYLRYVEALRAQIQEKM 875
+ EK+ +L+ QE + +EK+ RE++ LR E + +EKM
Sbjct: 266 EQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKM 319
Score = 34.3 bits (77), Expect = 0.57
Identities = 106/606 (17%), Positives = 249/606 (41%), Gaps = 68/606 (11%)
Query: 244 YQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRVQKVK 303
Y+N + N+EL + + +E L EK + L + E K K +++ K
Sbjct: 176 YRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVK----------ELKRK----LERAK 221
Query: 304 FKNPLF---VLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPDT 360
F P L EE +++ + + + ++ + L E +G + Q K
Sbjct: 222 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMRE-QEEKMRR 280
Query: 361 QAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQALL 420
Q ++ Q E Q E Q K Q ++ Q ++ E ++ Q+ Q
Sbjct: 281 QEKRLREQEKELREQEKELREQK-KLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER 339
Query: 421 TKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQ--DILPKYQDQNFLPKDQN 478
Q+ +++ +DQ + QD+ +++ + +++ + K Q++ + + +
Sbjct: 340 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Query: 479 FLSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNIL---PKYQGQDFLPK 535
+ ++ + + ++ + K ++ + +++ + Q LP+ + L K Q Q+
Sbjct: 400 KMREEEETMREQEEKMQKQEENMWEQEEKEW---QQQRLPEQKEKLWEQEKMQEQEEKIW 456
Query: 536 DQDFLSRDQHVL----PKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQG 591
+Q+ RDQ + K W K ++Q+ +Q +DQ Q++ +D+
Sbjct: 457 EQEEKIRDQEEMWGQEKKMWR-QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Query: 592 YLPKDQNILP---ICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMT 648
K++ + + Q + + + ++ K DQ+ +K+ +E +
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEK----KTWDQE-----EKMREEERMRER- 565
Query: 649 DEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFM--------REERVREELPLDYHQYV 700
++K RE+ + Q K Q+Q++ +Q +EE++ E+ + Q
Sbjct: 566 EKKMREEEEMMREQ--EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
Query: 701 VPKIQDQDS---PREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLST--EFQAPL 755
K+Q+Q+ +E+ + +E+ E R + ++ Q E + +
Sbjct: 624 EDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKM 683
Query: 756 AFQSDVDKEEDKKER---QKQYLRHRRLFMDIEREQVKEQQRQK-----EQKKKIEKIKK 807
Q + +E+++K R +K + + +++ E+ +E+ R+K +QK+K+++
Sbjct: 684 QGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLP 743
Query: 808 KREQEC 813
+ E+ C
Sbjct: 744 EHEERC 749
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/114 (28%), Positives = 66/114 (57%), Gaps = 4/114 (3%)
Query: 763 KEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILR 822
K+E+++ER ++ +RL E+E+ ++++R++E++++ + +++REQE AEQ R
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQE--R 724
Query: 823 MNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREK--EYLRYVEALRAQIQEK 874
E + +L E L+LQ+ + RE ++++K E R E + QEK
Sbjct: 725 RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 778
Score = 40.4 bits (93), Expect = 0.008
Identities = 45/221 (20%), Positives = 97/221 (43%), Gaps = 20/221 (9%)
Query: 670 DQDDIKNQQPASFMREERVR-------EELPLDYHQYVVPKIQDQDSPREQNKHIKLPSS 722
DQ D + P S R+ + EE L+ + P+ + SP +K ++ +
Sbjct: 435 DQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
Query: 723 FEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFM 782
F + R P + R + PL E +++R + R
Sbjct: 495 FLH-TVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKE---- 549
Query: 783 DIEREQVKEQQRQKEQKKKIEKIKKKREQ---ECYAAEQRILRMNFHEDPYSGEKLSEIL 839
E EQ++ Q+ ++++++++E++K KRE+ + A +R+ +M + +K ++I
Sbjct: 550 --EAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 607
Query: 840 AQLQLQEIKGTREKQQREK---EYLRYVEALRAQIQEKMQL 877
+ + + + E++ ++K + + VEA R Q +E +L
Sbjct: 608 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 648
Score = 38.9 bits (89), Expect = 0.023
Identities = 44/218 (20%), Positives = 94/218 (43%), Gaps = 32/218 (14%)
Query: 670 DQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIA 729
++D + + REER+R+ L V +++++ + + K ++ EK +
Sbjct: 560 EEDKRRRLEEVKLKREERLRKVLQARER---VEQMKEEKKKQIEQKFAQIDEKTEKAKEE 616
Query: 730 RGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIERE-- 787
R L+ E A +++ E +++++++ R R L + E
Sbjct: 617 R----------------LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 660
Query: 788 ----QVKEQQRQKEQKKKIE-------KIKKKREQECYAAEQRILRMNFHEDPYSGEKLS 836
Q K+++ Q+ +K E + +++REQE E+R E +L+
Sbjct: 661 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 720
Query: 837 EILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEK 874
E + + + ++ RE Q+REK E L+ +++EK
Sbjct: 721 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 758
Score = 37.7 bits (86), Expect = 0.051
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 11/190 (5%)
Query: 684 REERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRY 743
+EER+ EE + K+++ ++ R+Q + + ++ E R + + +
Sbjct: 614 KEERLAEEKAKK--KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 671
Query: 744 QSGLSTEFQAP-LAFQSDVDKEEDKKERQKQYLRHRRLFMDIERE-QVKEQQRQKEQKKK 801
Q L +A LA Q + ++ E ++ Q++ + RR E+E Q+ EQ+R++EQ++
Sbjct: 672 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 731
Query: 802 IEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYL 861
+ + + ++ ++ L+ E E+ + LA+ QLQE E++++ KE
Sbjct: 732 QAERELQEREKALRLQKEQLQRELEEKKKKEEQ--QRLAERQLQE-----EQEKKAKEAA 784
Query: 862 RYVEALRAQI 871
+AL +
Sbjct: 785 GASKALNVTV 794
Score = 33.5 bits (75), Expect = 0.97
Identities = 15/54 (27%), Positives = 36/54 (66%)
Query: 66 EEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQ 119
E+E +EQ R++QE + +++ + ++ +Q R R++++LQ E ++E ++ +Q
Sbjct: 694 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 747
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/114 (28%), Positives = 66/114 (57%), Gaps = 4/114 (3%)
Query: 763 KEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILR 822
K+E+++ER ++ +RL E+E+ ++++R++E++++ + +++REQE AEQ R
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQE--R 720
Query: 823 MNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREK--EYLRYVEALRAQIQEK 874
E + +L E L+LQ+ + RE ++++K E R E + QEK
Sbjct: 721 RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
Score = 42.7 bits (99), Expect = 0.002
Identities = 48/221 (21%), Positives = 100/221 (45%), Gaps = 24/221 (10%)
Query: 670 DQDDIKNQQPASFMREERVR-------EELPLDYHQYVVPKIQDQDSPREQNKHIKLPSS 722
DQ D + P S R+ + EE L+ + P+ + SP +K ++ +
Sbjct: 435 DQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRT 494
Query: 723 FEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFM 782
F + R P + R + PL D KE+++Q L + R
Sbjct: 495 FLH-TVQRNQMLMTPTSAPRSVMKSFIKRNTPLRM--------DPKEKERQRLENLR--R 543
Query: 783 DIEREQVKEQQRQKEQKKKIEKIKKKREQ---ECYAAEQRILRMNFHEDPYSGEKLSEIL 839
E EQ++ Q+ ++++++++E++K KRE+ + A +R+ +M + +K ++I
Sbjct: 544 KEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQID 603
Query: 840 AQLQLQEIKGTREKQQREK---EYLRYVEALRAQIQEKMQL 877
+ + + + E++ ++K + + VEA R Q +E +L
Sbjct: 604 EKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRL 644
Score = 38.9 bits (89), Expect = 0.023
Identities = 44/218 (20%), Positives = 94/218 (43%), Gaps = 32/218 (14%)
Query: 670 DQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIA 729
++D + + REER+R+ L V +++++ + + K ++ EK +
Sbjct: 556 EEDKRRRLEEVKLKREERLRKVLQARER---VEQMKEEKKKQIEQKFAQIDEKTEKAKEE 612
Query: 730 RGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIERE-- 787
R L+ E A +++ E +++++++ R R L + E
Sbjct: 613 R----------------LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH 656
Query: 788 ----QVKEQQRQKEQKKKIE-------KIKKKREQECYAAEQRILRMNFHEDPYSGEKLS 836
Q K+++ Q+ +K E + +++REQE E+R E +L+
Sbjct: 657 QELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLA 716
Query: 837 EILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEK 874
E + + + ++ RE Q+REK E L+ +++EK
Sbjct: 717 EQERRREQERLQAERELQEREKALRLQKEQLQRELEEK 754
Score = 37.7 bits (86), Expect = 0.051
Identities = 42/190 (22%), Positives = 91/190 (47%), Gaps = 11/190 (5%)
Query: 684 REERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRY 743
+EER+ EE + K+++ ++ R+Q + + ++ E R + + +
Sbjct: 610 KEERLAEEKAKK--KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEE 667
Query: 744 QSGLSTEFQAP-LAFQSDVDKEEDKKERQKQYLRHRRLFMDIERE-QVKEQQRQKEQKKK 801
Q L +A LA Q + ++ E ++ Q++ + RR E+E Q+ EQ+R++EQ++
Sbjct: 668 QERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERL 727
Query: 802 IEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYL 861
+ + + ++ ++ L+ E E+ + LA+ QLQE E++++ KE
Sbjct: 728 QAERELQEREKALRLQKEQLQRELEEKKKKEEQ--QRLAERQLQE-----EQEKKAKEAA 780
Query: 862 RYVEALRAQI 871
+AL +
Sbjct: 781 GASKALNVTV 790
Score = 33.5 bits (75), Expect = 0.97
Identities = 15/54 (27%), Positives = 36/54 (66%)
Query: 66 EEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQ 119
E+E +EQ R++QE + +++ + ++ +Q R R++++LQ E ++E ++ +Q
Sbjct: 690 EQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQ 743
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 46.2 bits (108), Expect = 1e-04
Identities = 47/200 (23%), Positives = 93/200 (46%), Gaps = 23/200 (11%)
Query: 667 KSQDQDDIKNQQPAS--FMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFE 724
K + Q+ +KNQ+ F R +R+ EE+PL Y +I+D D +Q + E
Sbjct: 681 KKELQERLKNQEKKIDYFERAKRL-EEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLE 739
Query: 725 KWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDI 784
+ + + DR + + ++ + + E++ + RH RL
Sbjct: 740 REKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEE----RHNRL---- 791
Query: 785 EREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQ- 843
+E++RQ++++++I ++K E+E AE+++L+ + K E L + Q
Sbjct: 792 -----EERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQE 846
Query: 844 ----LQEIKGTREKQQREKE 859
L+E++ R+K+QRE E
Sbjct: 847 RVKKLEEVE--RKKRQRELE 864
Score = 31.6 bits (70), Expect = 3.7
Identities = 28/129 (21%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Query: 689 REELPLDYHQYVVPKIQDQDSPREQNKHI-KLPSSFEKWEIARGNTPGVPLAYDRYQSGL 747
RE+ P+ H +P Q ++ + + K + I + LA Y
Sbjct: 502 REDAPIGPHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNS 561
Query: 748 STEFQAPLAFQSDVDKEEDKKE-----RQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKI 802
E Q LA + +++ +++ E R+K+ L R + R+ +E+ RQ+ ++++
Sbjct: 562 RKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREK 621
Query: 803 EKIKKKREQ 811
E+I ++ EQ
Sbjct: 622 ERILQEHEQ 630
Score = 31.6 bits (70), Expect = 3.7
Identities = 42/205 (20%), Positives = 91/205 (44%), Gaps = 29/205 (14%)
Query: 689 REELPLDYHQYVVPKIQ--DQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSG 746
RE+ L+ + + K++ +++ R++ K + ++ E + T +R +
Sbjct: 589 REKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKT-----VRERLEQI 643
Query: 747 LSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIK 806
TE A D+ ED +E ++ +++ +E+E+ + Q+R K Q+KKI+ +
Sbjct: 644 KKTELGAKAFKDIDI---EDLEELDPDFIMAKQV-EQLEKEKKELQERLKNQEKKIDYFE 699
Query: 807 KKREQE------CYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREK------- 853
+ + E EQRI M+ E ++ E + +QL+ K K
Sbjct: 700 RAKRLEEIPLIKSAYEEQRIKDMDLWE-----QQEEERITTMQLEREKALEHKNRMSRML 754
Query: 854 QQREKEYLRYVEALRAQIQEKMQLY 878
+ R+ +R A ++ +EK++ +
Sbjct: 755 EDRDLFVMRLKAARQSVYEEKLKQF 779
>gi|15826852 acyl-Coenzyme A binding domain containing 3 [Homo
sapiens]
Length = 528
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/116 (26%), Positives = 63/116 (54%), Gaps = 13/116 (11%)
Query: 761 VDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRI 820
++KEE +K+R+++ R RR + ER Q +E++R++E+++++ ++ E+E E+
Sbjct: 181 IEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERL----RREEEERRRIEEER 236
Query: 821 LRMNFHEDPYSGEKLSEILAQLQ---LQEIKGTREKQQ------REKEYLRYVEAL 867
LR+ + S+ Q Q Q+ G E+QQ +E+ Y +Y++ L
Sbjct: 237 LRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQL 292
Score = 33.1 bits (74), Expect = 1.3
Identities = 39/237 (16%), Positives = 98/237 (41%), Gaps = 32/237 (13%)
Query: 59 YTSAYLIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAM 118
Y +++ IE+E +E+ RK++E + +++ + R+ ++ R++++ ++ R ++E +
Sbjct: 175 YVASHKIEKEEQEKKRKEEEERRRREEEERERLQKEEEKRRREEEERL--RREEEERRRI 232
Query: 119 QSSATHLTSKRTSVFPN-NLNVAIGSSRLPPSLMPGDGIEDE----ENQNELFQQQAQAL 173
+ L ++ + N A+ + PG+ + + + Q + +QQ Q L
Sbjct: 233 EEERLRLEQQKQQIMAALNSQTAVQFQQYAAQQYPGNYEQQQILIRQLQEQHYQQYMQQL 292
Query: 174 SETMKQARHRLASFKTVIKKKGSVFPDDGRKSFL-----------------TREEVLSRK 216
+ + + + GS P + + + E+ L +
Sbjct: 293 YQVQLAQQQAALQKQQEVVVAGSSLPTSSKVNATVPSNMMSVNGQAKTHTDSSEKELEPE 352
Query: 217 PASTGINTGIRGELPIKVHQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGK 273
A + G + LP+ A P + Q D++E +++ S++T +G+
Sbjct: 353 AAEEALENGPKESLPV-------IAAP-SMWTRPQIKDFKEKIQQDADSVITVGRGE 401
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 45.4 bits (106), Expect = 2e-04
Identities = 162/895 (18%), Positives = 355/895 (39%), Gaps = 131/895 (14%)
Query: 65 IEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQKEGSIAMQSSATH 124
I ++ LR+ + + QK++ + Q+ L +++ +K + +E + + A+H
Sbjct: 1077 IRQQELSALRQDMQEAQGEQKEL----SAQMELLRQEVKEKEADFLAQEAQLLEELEASH 1132
Query: 125 LTSK--RTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQ--ALSETMKQA 180
+T + R S++ A RL + + + E+ Q QAQ +L ++QA
Sbjct: 1133 ITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQA 1192
Query: 181 RHRLASFKTVIKKKGSVFPD--------DGRKSFLTREEVLSRKPASTGINTGIRGELPI 232
+ + + G P +G +S + R P T ++
Sbjct: 1193 LGSVCESRPELSGGGDSAPSVWGLEPDQNGARS------LFKRGPLLTALSAEAVASALH 1246
Query: 233 KVHQGLLAAVPYQNYMENQELDYEE--PDYE-ESSSLVTDEKGKEDLFGRGQQDQQAIHS 289
K+HQ L ++ + +Q EE D E E S + T+ + + + Q+++
Sbjct: 1247 KLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEG 1306
Query: 290 EDKNKPFSRVQKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLET--- 346
+ + ++ + L + E +++ +G +++L A++ L AQ + L+
Sbjct: 1307 KQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKEN-LTAQVEHLQAAVV 1365
Query: 347 ----QGDLTGI--QSVKPDTQAVEMKVQVTEPE---GQAIEPEGQ-----------PIKT 386
Q GI + ++ A+++K + E E QA++ +G+ +
Sbjct: 1366 EARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLAL 1425
Query: 387 ETQGIMLKAQSIELEEGSI--VLKTQDFLPTNQALLT-----KNQDVLLKDHCV--LPKD 437
TQ + + + +E G I + K ++ LL+ +NQ+V L+ + L K
Sbjct: 1426 LTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKC 1485
Query: 438 QSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQ----NFLSRDQHVLPKDQDI 493
+S+L + LP V ++Q + + + L KD+ N L L K +
Sbjct: 1486 RSVL------EHLP--MAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQM 1537
Query: 494 LPKYQDQNFLPKDQNF--------LSRDQHVLPKDQNILPKYQGQ-------------DF 532
+ + Q K Q L + H + Q ++ + +GQ D
Sbjct: 1538 IESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDL 1597
Query: 533 LPKDQDFLSRDQ--HVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQDQDFLPRDQ 590
+ Q+ ++ H L +L + + RDQ V + + I + + ++ L +D
Sbjct: 1598 EERSQELQAQSSQIHDLESHSTVLAR----ELQERDQEVKSQREQIEELQRQKEHLTQD- 1652
Query: 591 GYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKEPYSDMTDE 650
L + L + ++R + VL + + K ++D + K+ +E ++T +
Sbjct: 1653 --LERRDQELMLQKER------IQVLEDQRTRQTKILEEDL--EQIKLSLRERGRELTTQ 1702
Query: 651 KGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSP 710
+ L + K + + + + ++ +E H + + +++DQ
Sbjct: 1703 R-----QLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQ 1757
Query: 711 REQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKER 770
+ Q H K+ E + + + + Q + QS +D+ + +
Sbjct: 1758 QLQGLHRKVG---ETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQ 1814
Query: 771 QKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPY 830
+ Q L +++EQ + Q +++ K+K + ++ EQ ++R + H++
Sbjct: 1815 RDQELEA------LQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKE-- 1866
Query: 831 SGEKLSEILA----QLQ-LQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLYNI 880
+L E LA ++Q L+E+ G + RE+E + + AL+ Q E+ Q + +
Sbjct: 1867 QARRLEEELAVEGRRVQALEEVLGDLRAESREQE--KALLALQQQCAEQAQEHEV 1919
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/130 (24%), Positives = 71/130 (54%), Gaps = 7/130 (5%)
Query: 744 QSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHR--RLFMDIEREQVKEQQRQKEQKKK 801
Q G + Q A + +V++ +K E+++ + + + +ERE+++ + R KEQ+ +
Sbjct: 838 QEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTE 897
Query: 802 IEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQ-EIKGTREKQQREKEY 860
+E I+ +RE+E AE + +M + E++S + LQ Q E+ ++ +R ++
Sbjct: 898 MEAIQAQREEERTQAESALCQMQLETEK---ERVSLLETLLQTQKELADASQQLERLRQD 954
Query: 861 LRYVEALRAQ 870
++ V+ L+ Q
Sbjct: 955 MK-VQKLKEQ 963
Score = 36.2 bits (82), Expect = 0.15
Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Query: 745 SGLSTEFQAPLAFQSDVDKE-EDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIE 803
+ L E + L + D+ K+ ED K + +RL +E+++E Q +K++E
Sbjct: 992 AALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELE 1051
Query: 804 KIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRY 863
+ K EQR+L + D ++LS + +Q E Q +KE
Sbjct: 1052 REKASLTLSLMEKEQRLLVLQ-EADSIRQQELSALRQDMQ--------EAQGEQKELSAQ 1102
Query: 864 VEALRAQIQEK 874
+E LR +++EK
Sbjct: 1103 MELLRQEVKEK 1113
Score = 32.7 bits (73), Expect = 1.7
Identities = 31/102 (30%), Positives = 49/102 (48%), Gaps = 13/102 (12%)
Query: 755 LAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECY 814
L +Q DV + + ++ + LRH++ EREQ+ E+ + ++ + + K+ QE
Sbjct: 2031 LRYQEDVQQLQQALAQRDEELRHQQ-----EREQLLEKSLAQRVQENMIQEKQNLGQERE 2085
Query: 815 AAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQR 856
E R L + E L LAQ + QEI RE QQR
Sbjct: 2086 EEEIRGLHQSVRE-------LQLTLAQKE-QEILELRETQQR 2119
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/228 (24%), Positives = 103/228 (45%), Gaps = 24/228 (10%)
Query: 669 QDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEI 728
+ +D + Q+ +EE++RE+ + Q + QD+ ++ + + + E
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 729 ARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKE-EDKKERQKQYLRHRRLFMDIERE 787
R R Q E + + Q + +E E+ + Q++ LR M E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 788 QVKEQ----QRQKE----QKKKIEKIKK--KREQECYAAEQRILRMNFHEDPYSGEKLSE 837
+++EQ QRQ+E Q++K + +K K+E++ + E+++ R EK+ E
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE--------EKMWE 514
Query: 838 ILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLYNITLPPL 885
++Q QE EK QR++E +R E Q +EKMQ + L L
Sbjct: 515 QEEKMQEQE-----EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557
Score = 36.6 bits (83), Expect = 0.11
Identities = 39/204 (19%), Positives = 98/204 (48%), Gaps = 16/204 (7%)
Query: 667 KSQDQDD-IKNQQPASFMREERVREELPLDYHQY--VVPKIQDQDSP-REQNKHI----- 717
K ++QD+ I+ Q+ + +EE++RE+ + K+++QD REQ + +
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 718 KLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRH 777
K+ E + V + + + + + + ++E+K RQ++ L+
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Query: 778 RRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSE 837
+ E + +++++ EQ++K+++ ++K +++ ++ +R+ E EK+ E
Sbjct: 495 EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-----EKMQE 549
Query: 838 ILAQLQLQEIKGTREKQQREKEYL 861
+++LQE++ K ++ E L
Sbjct: 550 --QEVRLQELEERLGKLGQKAELL 571
Score = 35.0 bits (79), Expect = 0.33
Identities = 24/110 (21%), Positives = 60/110 (54%), Gaps = 11/110 (10%)
Query: 761 VDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRI 820
+ ++E+K RQ++ + + + REQ + RQ+E+ ++ E+ +++E++ + E++I
Sbjct: 320 IREQEEKMWRQEEKMHEQE---EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 821 LRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQ 870
+ EK+ E ++ QE K ++++R+++ R + +R Q
Sbjct: 377 REQD--------EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418
Score = 33.1 bits (74), Expect = 1.3
Identities = 29/116 (25%), Positives = 63/116 (54%), Gaps = 11/116 (9%)
Query: 763 KEEDKKERQKQYLRHRRLFMDIEREQV-KEQQRQKEQKKKIEKIKKK--REQECYAAEQR 819
++E+K + Q++ + + L + + E++ +++++ EQ++KI + + K R++E ++
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 820 ILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKM 875
+R + EK+ E ++Q QE E+ R++E +R E R QEKM
Sbjct: 361 KIREQEEKMWRQEEKIREQDEKIQEQE-----EEMWRQEEKIREQEEKR---QEKM 408
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/228 (24%), Positives = 103/228 (45%), Gaps = 24/228 (10%)
Query: 669 QDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEI 728
+ +D + Q+ +EE++RE+ + Q + QD+ ++ + + + E
Sbjct: 343 EQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEE 402
Query: 729 ARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKE-EDKKERQKQYLRHRRLFMDIERE 787
R R Q E + + Q + +E E+ + Q++ LR M E E
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 788 QVKEQ----QRQKE----QKKKIEKIKK--KREQECYAAEQRILRMNFHEDPYSGEKLSE 837
+++EQ QRQ+E Q++K + +K K+E++ + E+++ R EK+ E
Sbjct: 463 KMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQE--------EKMWE 514
Query: 838 ILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQLYNITLPPL 885
++Q QE EK QR++E +R E Q +EKMQ + L L
Sbjct: 515 QEEKMQEQE-----EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQEL 557
Score = 36.6 bits (83), Expect = 0.11
Identities = 39/204 (19%), Positives = 98/204 (48%), Gaps = 16/204 (7%)
Query: 667 KSQDQDD-IKNQQPASFMREERVREELPLDYHQY--VVPKIQDQDSP-REQNKHI----- 717
K ++QD+ I+ Q+ + +EE++RE+ + K+++QD REQ + +
Sbjct: 375 KIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEE 434
Query: 718 KLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRH 777
K+ E + V + + + + + + ++E+K RQ++ L+
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQ 494
Query: 778 RRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSE 837
+ E + +++++ EQ++K+++ ++K +++ ++ +R+ E EK+ E
Sbjct: 495 EEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQE-----EKMQE 549
Query: 838 ILAQLQLQEIKGTREKQQREKEYL 861
+++LQE++ K ++ E L
Sbjct: 550 --QEVRLQELEERLGKLGQKAELL 571
Score = 35.0 bits (79), Expect = 0.33
Identities = 24/110 (21%), Positives = 60/110 (54%), Gaps = 11/110 (10%)
Query: 761 VDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRI 820
+ ++E+K RQ++ + + + REQ + RQ+E+ ++ E+ +++E++ + E++I
Sbjct: 320 IREQEEKMWRQEEKMHEQE---EKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKI 376
Query: 821 LRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQ 870
+ EK+ E ++ QE K ++++R+++ R + +R Q
Sbjct: 377 REQD--------EKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQ 418
Score = 31.2 bits (69), Expect = 4.8
Identities = 42/189 (22%), Positives = 87/189 (46%), Gaps = 20/189 (10%)
Query: 689 REELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLS 748
R+ L L+ ++ + + ++ E + ++L S EK EI N + +R Q L
Sbjct: 199 RDALSLELYRNTITDEELKEKNAELQEKLRLVES-EKSEIQL-NVKDLKRKLERAQLLLP 256
Query: 749 TEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKK 808
+ Q V+ + KE Q + + + E + QQ++++ ++ EKI+++
Sbjct: 257 QQ-------QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 809 REQECYAAEQRILRMNFHEDPY--SGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEA 866
E+ C ++ L++ E+ EK+ E Q ++I+ +K R++E +R E
Sbjct: 310 EEKMC----EQELKIREQEEKMWRQEEKMHE-----QEEKIREQEDKMWRQEEKIREQEE 360
Query: 867 LRAQIQEKM 875
+ +EKM
Sbjct: 361 KIREQEEKM 369
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 44.7 bits (104), Expect = 4e-04
Identities = 58/255 (22%), Positives = 118/255 (46%), Gaps = 41/255 (16%)
Query: 627 QDQDFLPKYQKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREE 686
Q++ + +K+H +E + +EK +E + + K ++Q++I Q+ +EE
Sbjct: 496 QEEKMWRQEEKIHEQEKIRE--EEKRQEQEEMWRQE---EKIREQEEIWRQKEKIHEQEE 550
Query: 687 RVREELPLDYHQYVVPKIQDQDSP-REQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQS 745
++R++ + Q K+ DQ+ REQ + + W R +
Sbjct: 551 KIRKQEEKMWRQE--EKMHDQEEKIREQEEKV--------W---------------RQEE 585
Query: 746 GLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQ---RQKEQKKKI 802
+ + + + + ++E+ + Q++ + + M + E+++EQ+ R++E+K +
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR- 644
Query: 803 EKIKKKREQECYAAEQRILRMNFHEDPY-SGEKLSEILAQLQLQEIKGTREKQQREKEYL 861
E+ KK REQE EQ + E + EK+ E ++Q QE EK +R++E +
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE-----EKMRRQEEKM 699
Query: 862 RYVEALRAQIQEKMQ 876
E Q +EKMQ
Sbjct: 700 WEQEVRLRQQEEKMQ 714
Score = 44.3 bits (103), Expect = 5e-04
Identities = 45/212 (21%), Positives = 104/212 (49%), Gaps = 22/212 (10%)
Query: 669 QDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEI 728
+ ++ ++ Q+ + +EE++RE L+ + KI++Q+ R++ + I+ ++ E
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRE---LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 477
Query: 729 ARGNTPGVPLAYD---RYQSGLSTEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIE 785
+ R Q + + Q + +EE ++E+++ + + ++
Sbjct: 478 KMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI----- 532
Query: 786 REQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQ 845
REQ +E RQKE+ + E+ +K+E++ + E+++ H+ EK+ E ++ Q
Sbjct: 533 REQ-EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKM-----HDQE---EKIREQEEKVWRQ 583
Query: 846 E--IKGTREKQQREKEYLRYVEALRAQIQEKM 875
E I+ EK + ++E +R E + + +EKM
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Score = 37.4 bits (85), Expect = 0.067
Identities = 55/237 (23%), Positives = 105/237 (44%), Gaps = 21/237 (8%)
Query: 649 DEKGREDFSL-ADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVVPKIQDQ 707
D G+E S+ A Q +++ + + QQ R+E +E + Q KI++Q
Sbjct: 329 DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWE-EKIQEQEEKIREQ 387
Query: 708 DSP-REQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDVDKEED 766
+ REQ + ++ WE R Q + E + + Q ++ E++
Sbjct: 388 EEKIREQEEKMRRQEEM-MWEKEEKM---------RRQEEMMWEKEEKMRRQEEMMWEKE 437
Query: 767 KKERQKQYLRHRRLFMDI------EREQVKEQQ-RQKEQKKKIEKIKKKREQECYAAEQR 819
+K R+ + H + + E E+++EQ+ RQ+++ K + +K REQE EQ
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497
Query: 820 ILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKEYLRYVEALRAQIQEKMQ 876
E + EK+ E + + +E+ EK + ++E R E + Q +EK++
Sbjct: 498 EKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQ-EEKIR 553
Score = 37.0 bits (84), Expect = 0.088
Identities = 86/496 (17%), Positives = 204/496 (41%), Gaps = 76/496 (15%)
Query: 354 QSVKPDTQAVEMKVQVTEPEGQAIEPEGQPIKT--ETQGIMLKAQSIELEEG-------S 404
+ +K ++ K+Q+ E E I+ + +K E ++L Q ++ E S
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 405 IVLKTQDFLPTNQALLTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDIL 464
+ K Q + N+ NQ K K Q K Q+Q+ R+Q ++Q+
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK 397
Query: 465 PKYQDQNFLPKDQNFLSRDQHVLPKDQDILPKYQDQNFLPKDQNF--LSRDQHVLPKDQN 522
+ Q++ K++ +++ + K++ + + Q++ K++ L H K +
Sbjct: 398 MRRQEEMMWEKEEKMRRQEEMMWEKEEKM--RRQEEMMWEKEEKIRELEEKMHEQEKIRE 455
Query: 523 ILPKYQGQDFLPKDQDFLSRDQHVLPKDWNILPKCQDQDFLPRDQGVLPKDQNILPICQD 582
K Q ++ + + + + Q K W K ++Q+ R+Q
Sbjct: 456 QEEKRQEEEKIREQE----KRQEQEAKMWRQEEKIREQEEKIREQ--------------- 496
Query: 583 QDFLPRDQGYLPKDQNILPICQDRDFLPRDLHVLSNDQNILPKCQDQDFLPKYQKVHFKE 642
++ + R + + + + I ++ + + ++ I + ++ + +K+H +E
Sbjct: 497 EEKMWRQEEKIHEQEKI----REEEKRQEQEEMWRQEEKIR---EQEEIWRQKEKIHEQE 549
Query: 643 PYSDMTDEK-GREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREELPLDYHQYVV 701
+EK R++ + D ++ I+ Q+ + +EE++RE+ Q
Sbjct: 550 EKIRKQEEKMWRQEEKMHD---------QEEKIREQEEKVWRQEEKIREQEEKIREQE-- 598
Query: 702 PKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLSTEFQAPLAFQSDV 761
KI++Q+ ++ + K+ EK Q E + + Q +
Sbjct: 599 EKIREQEEMTQEQEE-KMGEQEEKM---------------CEQEEKMQEQEEKMRRQEEK 642
Query: 762 DKEEDKKER-QKQYLRHRRLFMDIEREQVKEQQ--------RQKEQKKKIEKIKKKREQE 812
+E++KK R Q++ +R + M + E++ EQ+ + +EQ++K+ + ++K ++
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702
Query: 813 CYAAEQRILRMNFHED 828
Q+ +M H++
Sbjct: 703 EVRLRQQEEKMQEHQE 718
Score = 32.3 bits (72), Expect = 2.2
Identities = 77/464 (16%), Positives = 200/464 (43%), Gaps = 50/464 (10%)
Query: 64 LIEEELKEQLRKKQEALKHFQKQVKYRVNQQIRLRKKQQLQKSYERAQ-KEGSIAMQSSA 122
+ +EELKE+ K QE L+ + + +I+L K +L++ ERA+ +Q+ A
Sbjct: 275 ITDEELKEKNAKLQEKLQLVESE-----KSEIQLNVK-ELKRKLERAKLLLPQQQLQAEA 328
Query: 123 THLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQNELFQQQAQAL---SETMKQ 179
HL + SV S++L +E+ E N L QQQ + + E +++
Sbjct: 329 DHLGKELQSV----------SAKLQAQ------VEENELWNRLNQQQEEKMWRQEEKIQE 372
Query: 180 ARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLSRKPASTGINTGIRGELPIKVHQGLL 239
++ + I+++ + K +EE++ K + E K+ +
Sbjct: 373 WEEKIQEQEEKIREQEEKIREQEEK-MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRR--Q 429
Query: 240 AAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRGQQDQQAIHSEDKNKPFSRV 299
+ ++ + +EL EE +E+ +EK +E+ R Q+ +Q E + K + +
Sbjct: 430 EEMMWEKEEKIREL--EEKMHEQEKIREQEEKRQEEEKIREQEKRQ----EQEAKMWRQE 483
Query: 300 QKVKFKNPLFVLMEEEEQKQLHFEGLQDILPEAQDYFLEAQGDLLETQGDLTGIQSVKPD 359
+K++ + + E+EE+ E + + ++ + Q ++ + + ++
Sbjct: 484 EKIREQEE--KIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE------EKIREQ 535
Query: 360 TQAVEMKVQVTEPEGQAIEPEGQPIKTETQGIMLKAQSIELEEGSIVLKTQDFLPTNQAL 419
+ K ++ E E + + E + + E + + Q ++ E + Q+ Q
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEK---MHDQEEKIREQEEKVWRQEEKIREQEE 592
Query: 420 LTKNQDVLLKDHCVLPKDQSILLKYQDQDFLPRDQHVLHKDQDILPKYQDQNFLPKDQNF 479
+ Q+ +++ + ++Q + Q++ +++ + +++ K + Q ++Q
Sbjct: 593 KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE----KMRRQEEKIREQEK 648
Query: 480 LSRDQHVLPKDQDILPKYQDQNFLPKDQNFLSRDQHVLPKDQNI 523
R+Q ++Q+ + + Q++ +++ +++ + +++ +
Sbjct: 649 KIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 692
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 43.9 bits (102), Expect = 7e-04
Identities = 37/116 (31%), Positives = 66/116 (56%), Gaps = 10/116 (8%)
Query: 763 KEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKKREQECYAAEQRILR 822
K +D+K K+ + L D +EQ +E++RQ++++++I + +++RE+E EQR+
Sbjct: 597 KSQDRKSESKE--KRDILSFDKIKEQ-RERERQRQREREIRETERRREREQREREQRL-- 651
Query: 823 MNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQR---EKEYLRYVEALRAQIQEKM 875
FHE E L QL+ Q + RE+ +R E+E +R VE R + QE++
Sbjct: 652 EAFHERKEKARLQRERL-QLECQRQRLERERMERERLERERMR-VERERRKEQERI 705
Score = 40.8 bits (94), Expect = 0.006
Identities = 32/114 (28%), Positives = 63/114 (55%), Gaps = 9/114 (7%)
Query: 762 DKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQK-----KKIEKIKKKREQ-ECYA 815
DK ++++ER++Q R R + + ER + +E QR++EQ+ ++ EK + +RE+ +
Sbjct: 615 DKIKEQRERERQRQREREI-RETERRRERE-QREREQRLEAFHERKEKARLQRERLQLEC 672
Query: 816 AEQRILRMNFHEDPYSGEKLS-EILAQLQLQEIKGTREKQQREKEYLRYVEALR 868
QR+ R + E++ E + + + I RE+ +R++E LRY + R
Sbjct: 673 QRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERR 726
Score = 33.9 bits (76), Expect = 0.74
Identities = 18/55 (32%), Positives = 35/55 (63%), Gaps = 1/55 (1%)
Query: 759 SDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQR-QKEQKKKIEKIKKKREQE 812
SD + E KKE+ RH + + IE+ +K++++ +K+++KK E IKK+ + +
Sbjct: 493 SDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQ 547
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 43.9 bits (102), Expect = 7e-04
Identities = 55/258 (21%), Positives = 115/258 (44%), Gaps = 22/258 (8%)
Query: 51 PGSSEIPAYTSAYL-IEEELKEQLRKKQEALKHFQ-----KQVKYRVNQQIRLRKKQQLQ 104
P + + A A ++EE + Q R+++E +K + ++ + R+ Q+ R RKKQ+ +
Sbjct: 336 PSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEK 395
Query: 105 KSYERAQKEGSIAMQSS-ATHLTSKRTSVFPNNLNVAIGSSRLPPSLMPGDGIEDEENQN 163
+ ER +KEG + +S ++ T V + S P P I +++ +
Sbjct: 396 ERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRP---IYEDKKRK 452
Query: 164 ELFQQ-QAQALSETMKQARHRLASFKTVIKKKGSVFPDDGRKSFLTREEVLS--RKPAST 220
++ QQ +++ +SE+M+ + V +K+ + P + + T + L AS
Sbjct: 453 KIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASD 512
Query: 221 GINTGIRGELPIKVHQGLLAAVPYQNYMENQELDYEEPDYEESSSLVTDEKGKEDLFGRG 280
+ G KVH + + E +E + EE + +E S +E+G+ +
Sbjct: 513 EETEKVEGN---KVH------IEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD 563
Query: 281 QQDQQAIHSEDKNKPFSR 298
++D++ +D K +
Sbjct: 564 EEDEKVSDEKDSGKTLDK 581
Score = 38.5 bits (88), Expect = 0.030
Identities = 53/250 (21%), Positives = 101/250 (40%), Gaps = 30/250 (12%)
Query: 636 QKVHFKEPYSDMTDEKGREDFSLADYQCLPPKSQDQDDIKNQQPASFMREERVREE---- 691
+K KE DE+ + L + + L +DQ K Q EE V+ +
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRK--FEEETVKSKVTVD 288
Query: 692 ---LPLDYHQYVVPKIQDQDSPREQNKHIKLPSSFEKWEIARGNTPGVPLAYDRYQSGLS 748
+P + P + D+ ++ K K EK E + G A +
Sbjct: 289 TGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVK------ 342
Query: 749 TEFQAPLAFQSDVDKEEDKKERQKQYLRHRRLFMDIEREQVKEQQRQKEQKKKIEKIKKK 808
A Q + K ++++ERQK+ R ++ + KE++R +++K++ +K K+K
Sbjct: 343 -------AMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEK 395
Query: 809 REQECYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTR--EKQQREKEYLRYVEA 866
+E E ++L + E E A L+L + +G K K+ Y +
Sbjct: 396 ERKERLKKEGKLLTKSQREARARAE------ATLKLLQAQGVEVPSKDSLPKKRPIYEDK 449
Query: 867 LRAQIQEKMQ 876
R +I ++++
Sbjct: 450 KRKKIPQQLE 459
Score = 31.2 bits (69), Expect = 4.8
Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 16/118 (13%)
Query: 753 APLAFQSDVDKEEDKKERQ--KQYLRHRRLFMDIEREQV----KEQQRQKEQKKKIEK-- 804
A ++ K+ +KKER+ K+ +L E+E++ K+Q +QKE ++K E+
Sbjct: 221 ASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEET 280
Query: 805 IKKKREQE---CYAAEQRILRMNFHEDPYSGEKLSEILAQLQLQEIKGTREKQQREKE 859
+K K + A+E++ ED G+K + ++ KG +E++++EK+
Sbjct: 281 VKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKK-----DKKKKKGEKEEKEKEKK 333
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,711,533
Number of Sequences: 37866
Number of extensions: 1976349
Number of successful extensions: 17424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 482
Number of HSP's that attempted gapping in prelim test: 10069
Number of HSP's gapped (non-prelim): 4524
length of query: 951
length of database: 18,247,518
effective HSP length: 112
effective length of query: 839
effective length of database: 14,006,526
effective search space: 11751475314
effective search space used: 11751475314
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.