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Search of human proteins with 14249678
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14249678 RNA binding motif protein 17 [Homo sapiens]
(401 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224549005 RNA binding motif protein 17 [Homo sapiens] 798 0.0
gi|14249678 RNA binding motif protein 17 [Homo sapiens] 798 0.0
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 74 2e-13
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 74 2e-13
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 74 2e-13
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 52 1e-06
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 52 1e-06
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 50 4e-06
gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofo... 49 8e-06
gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isofor... 49 8e-06
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 49 1e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 48 1e-05
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 48 2e-05
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 47 3e-05
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 47 4e-05
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 47 4e-05
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 47 4e-05
gi|52426743 cisplatin resistance-associated overexpressed protei... 46 5e-05
gi|19923485 cisplatin resistance-associated overexpressed protei... 46 5e-05
gi|28467003 kinase interacting stathmin [Homo sapiens] 45 9e-05
gi|56549694 enabled homolog isoform a [Homo sapiens] 45 1e-04
gi|39930375 enabled homolog isoform b [Homo sapiens] 45 1e-04
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 44 3e-04
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 44 3e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 43 4e-04
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 43 4e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 43 4e-04
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 43 4e-04
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 43 4e-04
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 43 6e-04
>gi|224549005 RNA binding motif protein 17 [Homo sapiens]
Length = 401
Score = 798 bits (2062), Expect = 0.0
Identities = 401/401 (100%), Positives = 401/401 (100%)
Query: 1 MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRG 60
MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRG
Sbjct: 1 MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRG 60
Query: 61 GSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQ 120
GSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQ
Sbjct: 61 GSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQ 120
Query: 121 RQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTS 180
RQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTS
Sbjct: 121 RQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTS 180
Query: 181 LVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAH 240
LVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAH
Sbjct: 181 LVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAH 240
Query: 241 KIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKDASKKSDSNPLTEIL 300
KIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKDASKKSDSNPLTEIL
Sbjct: 241 KIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKDASKKSDSNPLTEIL 300
Query: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFE 360
KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFE
Sbjct: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFE 360
Query: 361 RVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV 401
RVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV
Sbjct: 361 RVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV 401
>gi|14249678 RNA binding motif protein 17 [Homo sapiens]
Length = 401
Score = 798 bits (2062), Expect = 0.0
Identities = 401/401 (100%), Positives = 401/401 (100%)
Query: 1 MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRG 60
MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRG
Sbjct: 1 MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRG 60
Query: 61 GSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQ 120
GSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQ
Sbjct: 61 GSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQ 120
Query: 121 RQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTS 180
RQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTS
Sbjct: 121 RQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTS 180
Query: 181 LVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAH 240
LVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAH
Sbjct: 181 LVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLANMGGTVAH 240
Query: 241 KIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKDASKKSDSNPLTEIL 300
KIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKDASKKSDSNPLTEIL
Sbjct: 241 KIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIVGDATEKDASKKSDSNPLTEIL 300
Query: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFE 360
KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFE
Sbjct: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFE 360
Query: 361 RVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV 401
RVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV
Sbjct: 361 RVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLAEQV 401
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 74.3 bits (181), Expect = 2e-13
Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 3/101 (2%)
Query: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEA---VRIFL 357
K + V++LRNMV ++D+DLE E EEC K+G V + +I++ +++A V+IF+
Sbjct: 415 KQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 474
Query: 358 EFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLA 398
EF KA+ LNGR+F GR V A Y+ ++F DL+
Sbjct: 475 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLS 515
Score = 30.0 bits (66), Expect = 3.9
Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 311 NMVGAGEVDEDL-EVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAV 369
N + V +DL + + K E +GK+ C + P + F+E+E+ +S+ AV
Sbjct: 183 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG-FIEYEKAQSSQDAV 241
Query: 370 VDLNGRYFGGRVVK 383
+N GG+ ++
Sbjct: 242 SSMNLFDLGGQYLR 255
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 74.3 bits (181), Expect = 2e-13
Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 3/101 (2%)
Query: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEA---VRIFL 357
K + V++LRNMV ++D+DLE E EEC K+G V + +I++ +++A V+IF+
Sbjct: 441 KQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 500
Query: 358 EFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLA 398
EF KA+ LNGR+F GR V A Y+ ++F DL+
Sbjct: 501 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLS 541
Score = 30.0 bits (66), Expect = 3.9
Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 311 NMVGAGEVDEDL-EVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAV 369
N + V +DL + + K E +GK+ C + P + F+E+E+ +S+ AV
Sbjct: 209 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG-FIEYEKAQSSQDAV 267
Query: 370 VDLNGRYFGGRVVK 383
+N GG+ ++
Sbjct: 268 SSMNLFDLGGQYLR 281
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 74.3 bits (181), Expect = 2e-13
Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 3/101 (2%)
Query: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEA---VRIFL 357
K + V++LRNMV ++D+DLE E EEC K+G V + +I++ +++A V+IF+
Sbjct: 458 KQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 517
Query: 358 EFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLA 398
EF KA+ LNGR+F GR V A Y+ ++F DL+
Sbjct: 518 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLS 558
Score = 30.0 bits (66), Expect = 3.9
Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 311 NMVGAGEVDEDL-EVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAV 369
N + V +DL + + K E +GK+ C + P + F+E+E+ +S+ AV
Sbjct: 226 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG-FIEYEKAQSSQDAV 284
Query: 370 VDLNGRYFGGRVVK 383
+N GG+ ++
Sbjct: 285 SSMNLFDLGGQYLR 298
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 51.6 bits (122), Expect = 1e-06
Identities = 36/115 (31%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 109 EKVVKRQR-EERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRK 167
EK+ +++R +E+ R++E ER+KE E+ ++R K++ R D + D+++D ERER K
Sbjct: 382 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK--EREKDREKDKEKDREREREK 439
Query: 168 RSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRS 222
+K+KE +D E D + R + K+ PP Y R RS
Sbjct: 440 EHEKDRD-KEKEKEQDKEKEREKDRSKEIDEK-RKKDKKSRTPPRSYNASRRSRS 492
Score = 40.8 bits (94), Expect = 0.002
Identities = 47/210 (22%), Positives = 87/210 (41%), Gaps = 30/210 (14%)
Query: 112 VKRQREERQRQRELERQKEIE---------EREKRR-----KDRHEASGFARRPDPDSDE 157
VK + E++R+RE ER+KE E EREK R KDR D D ++
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 158 DEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRP-----RSQSSKAAIPPP 212
+++ ++E+ + I +K + PR + SR R + S+++ P
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509
Query: 213 VYEEQDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSK 272
+ + +S PS +K +K + E+ ST++ +
Sbjct: 510 RTSKTIKRKSSRSPS--------PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 561
Query: 273 RGGKIIVGDAT---EKDASKKSDSNPLTEI 299
G + + ++T EK+ +K+ DS+ E+
Sbjct: 562 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEV 591
Score = 32.0 bits (71), Expect = 1.0
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGG 172
K++ + R+R++ R R+KR+ R + R + D +++ + E+ER K G
Sbjct: 356 KKRSKSRERRKSRSRS---HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG 412
Query: 173 AAIAPPTSLVEKDKELPRDFPYEED-SRPRSQSSKAAIPPPVYEEQDRPR 221
+K++E R+ E+D R R + + +EQD+ +
Sbjct: 413 -----KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK 457
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 51.6 bits (122), Expect = 1e-06
Identities = 36/115 (31%), Positives = 60/115 (52%), Gaps = 5/115 (4%)
Query: 109 EKVVKRQR-EERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRK 167
EK+ +++R +E+ R++E ER+KE E+ ++R K++ R D + D+++D ERER K
Sbjct: 266 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDK--EREKDREKDKEKDREREREK 323
Query: 168 RSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRS 222
+K+KE +D E D + R + K+ PP Y R RS
Sbjct: 324 EHEKDRD-KEKEKEQDKEKEREKDRSKEIDEK-RKKDKKSRTPPRSYNASRRSRS 376
Score = 40.8 bits (94), Expect = 0.002
Identities = 47/210 (22%), Positives = 87/210 (41%), Gaps = 30/210 (14%)
Query: 112 VKRQREERQRQRELERQKEIE---------EREKRR-----KDRHEASGFARRPDPDSDE 157
VK + E++R+RE ER+KE E EREK R KDR D D ++
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 158 DEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRP-----RSQSSKAAIPPP 212
+++ ++E+ + I +K + PR + SR R + S+++ P
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 393
Query: 213 VYEEQDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSK 272
+ + +S PS +K +K + E+ ST++ +
Sbjct: 394 RTSKTIKRKSSRSPS--------PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 445
Query: 273 RGGKIIVGDAT---EKDASKKSDSNPLTEI 299
G + + ++T EK+ +K+ DS+ E+
Sbjct: 446 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEV 475
Score = 32.0 bits (71), Expect = 1.0
Identities = 25/110 (22%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGG 172
K++ + R+R++ R R+KR+ R + R + D +++ + E+ER K G
Sbjct: 240 KKRSKSRERRKSRSRS---HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERG 296
Query: 173 AAIAPPTSLVEKDKELPRDFPYEED-SRPRSQSSKAAIPPPVYEEQDRPR 221
+K++E R+ E+D R R + + +EQD+ +
Sbjct: 297 -----KNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK 341
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 50.1 bits (118), Expect = 4e-06
Identities = 41/136 (30%), Positives = 66/136 (48%), Gaps = 13/136 (9%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPD---SDEDEDYERER 165
E+ R+RE RQR+RE ER+ E ++ +RRK+ E A+R + D D D + ERE+
Sbjct: 420 ERERDRERERRQREREREREHERDKERQRRKEEWERER-AKRDEKDRQHRDRDREKEREK 478
Query: 166 RKRSMGGAAIAPPTSLVEKDK--------ELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQ 217
K + PP+ E K ++ R +++ R RS+S K + V +
Sbjct: 479 EKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWR-RSKSPKKKLGVSVSPSR 537
Query: 218 DRPRSPTGPSNSFLAN 233
R R T S++ +N
Sbjct: 538 ARRRRKTSASSASASN 553
Score = 49.7 bits (117), Expect = 5e-06
Identities = 39/126 (30%), Positives = 61/126 (48%), Gaps = 19/126 (15%)
Query: 104 FPNDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYER 163
+ N E+ +R+RE RQR+RE ER+++ ERE+R+++R E R E++ER
Sbjct: 398 YHNYRERERERERENRQRERERERERD-RERERRQRER-EREREHERDKERQRRKEEWER 455
Query: 164 ERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPR-- 221
ER KR EKD++ RD E++ K P P + + P+
Sbjct: 456 ERAKRD-------------EKDRQ-HRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKE 501
Query: 222 -SPTGP 226
+ TGP
Sbjct: 502 AATTGP 507
Score = 34.3 bits (77), Expect = 0.21
Identities = 27/125 (21%), Positives = 54/125 (43%), Gaps = 11/125 (8%)
Query: 106 NDYEKVVKRQREERQRQRELERQKEIEEREK-RRKDRHEASGFARRPDPDSDEDEDYERE 164
++ +K +R++EE +R+R +K+ + R++ R K+R + G +P P S + + E
Sbjct: 440 HERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKG---KPKPRSPQPPSRQAE 496
Query: 165 RRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPT 224
K+ A P ++ K+ P+ P+ + + P + S
Sbjct: 497 PPKKE--AATTGPQVKRADEWKD-----PWRRSKSPKKKLGVSVSPSRARRRRKTSASSA 549
Query: 225 GPSNS 229
SNS
Sbjct: 550 SASNS 554
>gi|60279268 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform
b [Homo sapiens]
Length = 471
Score = 48.9 bits (115), Expect = 8e-06
Identities = 38/103 (36%), Positives = 50/103 (48%), Gaps = 12/103 (11%)
Query: 303 PTKVVLLRNMVGAGEVDEDLEVE-----TKEECEKYGKVGKCVIFEIPGAPDDEAV---- 353
PT+V+ L NMV E+ +D E E ++EC KYG V EIP D V
Sbjct: 370 PTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKS---IEIPRPVDGVEVPGCG 426
Query: 354 RIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLD 396
+IF+EF V KA+ L GR F RVV + + D + D
Sbjct: 427 KIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRD 469
>gi|6005926 U2 (RNU2) small nuclear RNA auxiliary factor 2 isoform a
[Homo sapiens]
Length = 475
Score = 48.9 bits (115), Expect = 8e-06
Identities = 38/103 (36%), Positives = 50/103 (48%), Gaps = 12/103 (11%)
Query: 303 PTKVVLLRNMVGAGEVDEDLEVE-----TKEECEKYGKVGKCVIFEIPGAPDDEAV---- 353
PT+V+ L NMV E+ +D E E ++EC KYG V EIP D V
Sbjct: 374 PTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKS---IEIPRPVDGVEVPGCG 430
Query: 354 RIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLD 396
+IF+EF V KA+ L GR F RVV + + D + D
Sbjct: 431 KIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYHRRD 473
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 48.5 bits (114), Expect = 1e-05
Identities = 38/140 (27%), Positives = 67/140 (47%), Gaps = 18/140 (12%)
Query: 107 DYEKVVKRQREERQRQRELERQKEIE-EREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
D EK +R+REER+R+RE ER++E E ERE+ R + +R D D+ D RE+
Sbjct: 744 DREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREK 803
Query: 166 RKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTG 225
R+ + +D+ PRD E S+ R ++ + P + R R +
Sbjct: 804 REE-------------IREDRN-PRDGHDERKSKKRYRNEGS---PSPRQSPKRRREHSP 846
Query: 226 PSNSFLANMGGTVAHKIMQK 245
S+++ + H+++ +
Sbjct: 847 DSDAYNSGDDKNEKHRLLSQ 866
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/100 (32%), Positives = 46/100 (46%), Gaps = 20/100 (20%)
Query: 107 DYEKVVKRQRE---ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYER 163
D E+ R+RE ER+R RE E+++E+E R ++R R D D D D + ER
Sbjct: 680 DRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERER 739
Query: 164 ERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQ 203
ER E+D+E R+ EE R R +
Sbjct: 740 ER-----------------ERDREKEREREREERERERER 762
Score = 39.3 bits (90), Expect = 0.006
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 17/102 (16%)
Query: 109 EKVVKRQR-EERQRQRELERQKEIE-------EREKRRKDRHEASGFARRPDPDSDEDED 160
E+ ++R+R ER+R+RE ER +E + ERE+ R+ E R + + + + +
Sbjct: 704 ERELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERE 763
Query: 161 YERER-RKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPR 201
ERER R+R A E+DKE R +E+ + R
Sbjct: 764 RERERERERERERAR--------ERDKERERQRDWEDKDKGR 797
Score = 38.5 bits (88), Expect = 0.011
Identities = 46/197 (23%), Positives = 78/197 (39%), Gaps = 23/197 (11%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER-RK 167
+++ +R R E R+RE ER+ + +R DR + R D D + + ERER ++
Sbjct: 1297 DRLQERDRYEHDRERERERR----DTRQREWDRDADKDWPRNRDRDRLRERERERERDKR 1352
Query: 168 RSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPS 227
R + + VE+D++ RD +E + +A + E + R S
Sbjct: 1353 RDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKL------EGEHERDLESTS 1406
Query: 228 NSFLA--------NMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKIIV 279
LA ++G + K E G E L A S+ + G + I
Sbjct: 1407 RDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPIS 1466
Query: 280 GDATEK----DASKKSD 292
D ++ DA K+ D
Sbjct: 1467 DDELDEILAGDAEKRED 1483
Score = 35.4 bits (80), Expect = 0.092
Identities = 23/107 (21%), Positives = 47/107 (43%), Gaps = 1/107 (0%)
Query: 115 QREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAA 174
+R+ER+ +R ++R + + R +DR R + + + D + E+E R+ A
Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKE-RELERERAR 713
Query: 175 IAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPR 221
E+D+E RD ++ + + + EE++R R
Sbjct: 714 EREREREKERDRERDRDRDHDRERERERERDREKEREREREERERER 760
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/119 (26%), Positives = 59/119 (49%), Gaps = 19/119 (15%)
Query: 109 EKVVKRQRE-ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRK 167
E++ +R+RE ER+R++ELE+++E E ++R KDR + + + ++ + E+ER++
Sbjct: 502 EEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQ 561
Query: 168 RSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAA---IPPPVYEEQDRPRSP 223
EK+KEL R E++ + + K EE+ PR P
Sbjct: 562 ---------------EKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREP 605
Score = 33.5 bits (75), Expect = 0.35
Identities = 25/113 (22%), Positives = 52/113 (46%), Gaps = 19/113 (16%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ KR+ EE +R +E Q++ EK ++ + ++P P+ + + E+ER +
Sbjct: 460 ERARKRREEE---ERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERERE 516
Query: 169 SMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPR 221
+EK++E R+ E+D + + K + +EQ++ R
Sbjct: 517 KE-----------LEKEQEQEREKEREKDRERQQEKEK-----ELEKEQEKQR 553
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 9/122 (7%)
Query: 109 EKVVKRQRE---ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
EK R+RE ER+R+RE ER++E E +R ++R ++ D + DE++ YER +
Sbjct: 386 EKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK 445
Query: 166 RKRSMGGAAIAPPTSLVE---KDKELPRDFPYE---EDSRPRSQSSKAAIPPPVYEEQDR 219
+R + A L ++++ R++ E E+ R R + +A E+ D
Sbjct: 446 LERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDD 505
Query: 220 PR 221
R
Sbjct: 506 DR 507
Score = 47.4 bits (111), Expect = 2e-05
Identities = 21/61 (34%), Positives = 37/61 (60%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ +R+R ER+R+RE ER++E E+ +R ++R + D D D + D +R+R +
Sbjct: 315 ERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERS 374
Query: 169 S 169
S
Sbjct: 375 S 375
Score = 47.0 bits (110), Expect = 3e-05
Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 4/114 (3%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER-RK 167
E+ +R+RE R+R+RE ER++E E+ ++R ++R R + D D D + +R+R R+
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRE 372
Query: 168 RSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPR 221
RS + +D+E R+ E R R + + E++R R
Sbjct: 373 RSSDRNKDRSRSREKSRDRERERE---RERERERERERERERERERERERERER 423
Score = 44.7 bits (104), Expect = 2e-04
Identities = 32/114 (28%), Positives = 55/114 (48%), Gaps = 21/114 (18%)
Query: 112 VKRQREERQRQRELERQKEIEEREK-RRKDRHEASGFARRPDPDSDEDEDYERERRKRSM 170
++++R ER+R+RE ER++ ERE+ R ++R + R + D D D ER+R
Sbjct: 305 IEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR----- 359
Query: 171 GGAAIAPPTSLVEKDKELPRDFPYEEDS---RPRSQSSKAAIPPPVYEEQDRPR 221
++D+E RD E S + RS+S + + E++R R
Sbjct: 360 ------------DRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERER 401
Score = 38.1 bits (87), Expect = 0.014
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 13/128 (10%)
Query: 107 DYEKVVKRQREER-----------QRQRELERQKEIEEREKRRKDRHEASGFARRPDPDS 155
+ EK + + ER +R+RE ER+KE E +R +DR R D D
Sbjct: 304 EIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDR 363
Query: 156 DEDEDYERERRK-RSMGGAAIAPPTSLVEKDKELPRDFPYE-EDSRPRSQSSKAAIPPPV 213
+ D D +RER R+ + + E+++E R+ E E R R + +
Sbjct: 364 ERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERER 423
Query: 214 YEEQDRPR 221
E+D+ R
Sbjct: 424 EREKDKKR 431
Score = 35.0 bits (79), Expect = 0.12
Identities = 23/98 (23%), Positives = 46/98 (46%), Gaps = 16/98 (16%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ K+++E ++ ++E ++ ERE+ R++R R + + + + + ER+R +
Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR- 351
Query: 169 SMGGAAIAPPTSLVEKDKELPRDFPYEED-SRPRSQSS 205
++ KE RD E D R R +SS
Sbjct: 352 --------------DRTKERDRDRDRERDRDRDRERSS 375
Score = 35.0 bits (79), Expect = 0.12
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 5/93 (5%)
Query: 115 QREERQRQRELERQKEIEEREKRRKDRHEASGFAR-RPDPDSDEDEDYERERRKRSMGGA 173
Q+ R R++E+E + +REK + A PDPD+ E + E+E +R
Sbjct: 519 QKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDA-ELQRMEQEAERRRQPQI 577
Query: 174 AIAPPTSLVE---KDKELPRDFPYEEDSRPRSQ 203
P + E ++KE R+ P EE+ P +
Sbjct: 578 KQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610
Score = 32.0 bits (71), Expect = 1.0
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 7/120 (5%)
Query: 61 GSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQ 120
GS+ +++ D + A +D E+ L E P + +++ + RQ
Sbjct: 515 GSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQ 574
Query: 121 RQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAPPTS 180
Q + E + E EE EK+ K+ +R +P +E+E ++ K ++ + AP S
Sbjct: 575 PQIKQEPESEEEEEEKQEKEE-------KREEPMEEEEEPEQKPCLKPTLRPISSAPSVS 627
Score = 29.6 bits (65), Expect = 5.1
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
Query: 117 EERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIA 176
E R+R++ E +KE E E+RR++ + + + D D+D D + R G+A+
Sbjct: 465 EIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYR-----GSAL- 518
Query: 177 PPTSLVEKDKELPRD 191
L +++KE+ D
Sbjct: 519 -QKRLRDREKEMEAD 532
Score = 29.3 bits (64), Expect = 6.6
Identities = 25/111 (22%), Positives = 46/111 (41%), Gaps = 18/111 (16%)
Query: 118 ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGAAIAP 177
+ ++ E E+ K+ +ER++ K+R E R + + + ERER +
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERERER---------- 335
Query: 178 PTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSN 228
EK+KE R+ E R R ++ + ++DR R + N
Sbjct: 336 -----EKEKERERE---RERDRDRDRTKERDRDRDRERDRDRDRERSSDRN 378
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 47.0 bits (110), Expect = 3e-05
Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 13/118 (11%)
Query: 107 DYEKVVKRQRE---ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYER 163
D EK +RQ+E +RQR+RE ER+ E + +R+++R + R D D + + +R
Sbjct: 51 DREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
Query: 164 ERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPR 221
R + GG E+DK+ R+ E + R R + + E DR R
Sbjct: 111 NRERNRKGGR---------ERDKQTERERDRERE-RQRQRERERQRQRERKRETDRER 158
Score = 41.6 bits (96), Expect = 0.001
Identities = 28/71 (39%), Positives = 42/71 (59%), Gaps = 10/71 (14%)
Query: 107 DYEKVVKRQRE-ERQRQRELERQKEIE-----EREKRRKDRHEASGFARRPDPDSDEDED 160
D E+ +RQRE ERQRQRE +R+ + E ERE+R+K+R + R+ + + E+
Sbjct: 131 DRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKK----ERKKERKEKKKEE 186
Query: 161 YERERRKRSMG 171
RE +KR G
Sbjct: 187 KRREDKKRKWG 197
Score = 40.0 bits (92), Expect = 0.004
Identities = 40/152 (26%), Positives = 60/152 (39%), Gaps = 29/152 (19%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGG 172
K ER RQRE E Q E E R ++R DRH + D D + ERER+K
Sbjct: 15 KETERERDRQRERENQTERENRHRQR-DRHR--------ERDRQTDREKERERQK----- 60
Query: 173 AAIAPPTSLVEKDKELPRDFPYEEDS-----RPRSQSSKAAIPPPVYEEQDRPRSPTGPS 227
E+D++ R+ E ++ R R + K +++DR R
Sbjct: 61 ----------ERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR 110
Query: 228 NSFLANMGGTVAHKIMQKYGFREGQGLGKHEQ 259
N GG K ++ RE + + E+
Sbjct: 111 NRERNRKGGRERDKQTERERDRERERQRQRER 142
Score = 39.7 bits (91), Expect = 0.005
Identities = 21/63 (33%), Positives = 40/63 (63%), Gaps = 6/63 (9%)
Query: 109 EKVVKRQRE---ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
+K +R+R+ ERQRQRE ERQ++ RE++R+ E +A R + + ++ ++ER
Sbjct: 123 DKQTERERDRERERQRQRERERQRQ---RERKRETDRERQRWAEREERKKERKKERKKER 179
Query: 166 RKR 168
+++
Sbjct: 180 KEK 182
Score = 38.1 bits (87), Expect = 0.014
Identities = 29/118 (24%), Positives = 54/118 (45%), Gaps = 14/118 (11%)
Query: 109 EKVVKRQREERQRQ----RELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERE 164
E+ + +RE R RQ RE +RQ + E+ +R+K+R R + +++ + +R+
Sbjct: 26 ERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQ 85
Query: 165 RRKRSMGGAAIAPPTSLVEKDKELPRDFPYEED-SRPRSQSSKAAIPPPVYEEQDRPR 221
R ++ E+DK+ R+ E D +R R++ E+DR R
Sbjct: 86 RERKRQTDR---------ERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRER 134
Score = 36.2 bits (82), Expect = 0.054
Identities = 33/124 (26%), Positives = 54/124 (43%), Gaps = 24/124 (19%)
Query: 106 NDYEKVVKRQREERQRQR--------ELERQK----------EIEEREKRRKDRHEASGF 147
N E+ + ++ +R R+R E ERQK E E +R+++R
Sbjct: 29 NQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRER 88
Query: 148 ARRPDPDSDEDEDYERER-----RKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRS 202
R+ D + D+D D ER+R R+R+ G + E+D+E R E + R R
Sbjct: 89 KRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERE-RQRQ 147
Query: 203 QSSK 206
+ K
Sbjct: 148 RERK 151
Score = 33.9 bits (76), Expect = 0.27
Identities = 14/56 (25%), Positives = 31/56 (55%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
+ ++ R+R ++ ER+++ E +R+++R R+ + D + ERE RK+
Sbjct: 114 RNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKK 169
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 46.6 bits (109), Expect = 4e-05
Identities = 29/99 (29%), Positives = 47/99 (47%), Gaps = 12/99 (12%)
Query: 114 RQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGGA 173
R+REER+R R+ +RQKE E + ++ +D + R + D + + ER R + G
Sbjct: 383 REREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGR 442
Query: 174 AIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPP 212
E+D+E D + R R +S+ PPP
Sbjct: 443 ---------ERDRERQTD---RQAGRQRKRSTLYVNPPP 469
Score = 43.1 bits (100), Expect = 4e-04
Identities = 31/121 (25%), Positives = 54/121 (44%), Gaps = 10/121 (8%)
Query: 109 EKVVKRQRE-ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER-- 165
++ +R RE ER+R+R+ ER++E E KR ++R R+ + + D +++ ER+R
Sbjct: 288 QRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Query: 166 -------RKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQD 218
R R G E+++E R E + R R + E+D
Sbjct: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Query: 219 R 219
R
Sbjct: 408 R 408
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/143 (28%), Positives = 58/143 (40%), Gaps = 31/143 (21%)
Query: 107 DYEKVVKRQRE-ERQRQRELERQKEIE---------------EREKRRKDRHEASG---- 146
D EK +RQ + ERQRQ E RQKE E E+E + +DRH G
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 147 ----------FARRPDPDSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEE 196
R+ D + D ERER K++ A T +K++E RD +
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER-DKERERERDRDRDR 272
Query: 197 DSRPRSQSSKAAIPPPVYEEQDR 219
D R + + + E+DR
Sbjct: 273 DRRQKERERQTDRKRQRRTERDR 295
Score = 40.4 bits (93), Expect = 0.003
Identities = 19/64 (29%), Positives = 37/64 (57%), Gaps = 6/64 (9%)
Query: 106 NDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
+D E+ +++RE R+ +R+ ER+ + + +R KDRH R+ D + D E+ER
Sbjct: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRH------RKRDRHRERQRDREKER 105
Query: 166 RKRS 169
+++
Sbjct: 106 ERQT 109
Score = 40.0 bits (92), Expect = 0.004
Identities = 22/62 (35%), Positives = 37/62 (59%), Gaps = 4/62 (6%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREK---RRKDRHEASGFARRPDPDSDEDEDYERER 165
+K +R+RE+RQ +RE +R++E REK R++DRH R + + D + +R+R
Sbjct: 59 QKERERRREKRQTERETDRKRE-RRREKDRHRKRDRHRERQRDREKERERQTDRERDRQR 117
Query: 166 RK 167
K
Sbjct: 118 EK 119
Score = 38.9 bits (89), Expect = 0.008
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
Query: 113 KRQRE-ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMG 171
KRQ + ER RQR+ ER++E + +R +R R + D D D D ++ R+R
Sbjct: 225 KRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTD 284
Query: 172 GAAIAPPTSLVEKDKELPRDFPYE-EDSRPRSQSSKAAIPPPVYEEQDRPR 221
E+D+E R + E R R ++ K E++R R
Sbjct: 285 ----RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Score = 35.8 bits (81), Expect = 0.071
Identities = 19/85 (22%), Positives = 43/85 (50%), Gaps = 11/85 (12%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGG 172
+ ++ +R R+R+ +R+KE E + R +DR R+ + + + + + ER R +++ G
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG- 145
Query: 173 AAIAPPTSLVEKDKELPRDFPYEED 197
++++E RD E +
Sbjct: 146 ----------QRERERQRDAEKERE 160
Score = 34.3 bits (77), Expect = 0.21
Identities = 23/108 (21%), Positives = 48/108 (44%), Gaps = 9/108 (8%)
Query: 97 ADEYDPMFPNDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSD 156
A E + + E+ R R+ +RQ+E ERQ + + + + +DR R+ + + +
Sbjct: 251 ASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERE 310
Query: 157 EDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQS 204
+ + +RER + E+ +E RD E + + + Q+
Sbjct: 311 RERNRKRERERERERER---------ERQRETERDREKERERKRKRQT 349
Score = 33.9 bits (76), Expect = 0.27
Identities = 16/63 (25%), Positives = 35/63 (55%), Gaps = 3/63 (4%)
Query: 109 EKVVKRQRE---ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
E+ R+R+ E++R R+ ER++E E +R +DR R D++++ + + +R
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDR 165
Query: 166 RKR 168
++
Sbjct: 166 ERQ 168
Score = 33.9 bits (76), Expect = 0.27
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 18/109 (16%)
Query: 99 EYDPMFPNDYEKVVKRQREERQRQRELER------QKEIEEREKRRKDRHEASGFARRPD 152
E D + E+ + + +RQ++RE + Q+E E++ +R KDR G R +
Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRE 435
Query: 153 PDSDEDEDYERER-------RKRSMGGAAIAPP-----TSLVEKDKELP 189
+ + + +RER R+R + PP + +V+ D P
Sbjct: 436 REKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRP 484
Score = 33.5 bits (75), Expect = 0.35
Identities = 19/57 (33%), Positives = 31/57 (54%), Gaps = 1/57 (1%)
Query: 114 RQRE-ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRS 169
RQRE ER RQ+E ER+ E E R + R+ D + + + +RER++++
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
Score = 32.7 bits (73), Expect = 0.60
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 10/71 (14%)
Query: 107 DYEKVVKRQRE-ERQRQRELERQKEIE---------EREKRRKDRHEASGFARRPDPDSD 156
D ++ +RQR+ E++R+R+ +R+++ + EREK R++R E + + D
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Query: 157 EDEDYERERRK 167
+ RER +
Sbjct: 204 RHSERGRERER 214
Score = 32.0 bits (71), Expect = 1.0
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 109 EKVVKRQRE-ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRK 167
EK RQ+E ER+ +RE ER ++ + +R ++R + R D + ER R+K
Sbjct: 118 EKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
Score = 32.0 bits (71), Expect = 1.0
Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 3/56 (5%)
Query: 115 QRE-ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRS 169
QRE ERQR E ER+++ + +R+ +R+ R + + E + ER+R K +
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQK--EREREKNRQERRERERQREKEN 199
Score = 31.6 bits (70), Expect = 1.3
Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 108 YEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDS----DEDEDYER 163
+ K + + +R R++E ERQ + E +R K+R+ R + + D D +R
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 164 ERRKR 168
ER ++
Sbjct: 148 ERERQ 152
Score = 31.2 bits (69), Expect = 1.7
Identities = 26/128 (20%), Positives = 52/128 (40%), Gaps = 12/128 (9%)
Query: 99 EYDPMFPNDYEKVVKRQRE-----ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDP 153
E D + + +R+RE ER R R+ + Q+E E + K+R + R+
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQT 171
Query: 154 DSDEDEDYERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPV 213
+ + ++ ERE+ ++ +++KE + + E R R + +
Sbjct: 172 ERNRQKEREREKNRQERRERE-------RQREKENKTEDRHSERGRERERERETETETER 224
Query: 214 YEEQDRPR 221
+ DR R
Sbjct: 225 KRQTDRER 232
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 46.6 bits (109), Expect = 4e-05
Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 15/115 (13%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDS---DEDEDYERER 165
E+ +RQ+E QR+RE E ++ +EE E+RRK+ E RR + + + +++Y R +
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEE----RRRAEEEKRRVEREQEYIRRQ 471
Query: 166 RKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRP 220
+ + L E+ L + RP Q S+ PPP +E+ +P
Sbjct: 472 LEEEQRHLEVLQQQLLQEQAMLL------HDHRRPHPQHSQQ--PPPPQQERSKP 518
Score = 28.9 bits (63), Expect = 8.6
Identities = 15/61 (24%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 112 VKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDED----YERERRK 167
++ Q+E ++R L RQ+ ++E++ R ++ ++ A R + E E++RR+
Sbjct: 357 LRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRE 416
Query: 168 R 168
R
Sbjct: 417 R 417
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 46.6 bits (109), Expect = 4e-05
Identities = 32/115 (27%), Positives = 56/115 (48%), Gaps = 15/115 (13%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDS---DEDEDYERER 165
E+ +RQ+E QR+RE E ++ +EE E+RRK+ E RR + + + +++Y R +
Sbjct: 416 EREARRQQEREQRRREQEEKRRLEELERRRKEEEE----RRRAEEEKRRVEREQEYIRRQ 471
Query: 166 RKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRP 220
+ + L E+ L + RP Q S+ PPP +E+ +P
Sbjct: 472 LEEEQRHLEVLQQQLLQEQAMLL------HDHRRPHPQHSQQ--PPPPQQERSKP 518
Score = 28.9 bits (63), Expect = 8.6
Identities = 15/61 (24%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 112 VKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDED----YERERRK 167
++ Q+E ++R L RQ+ ++E++ R ++ ++ A R + E E++RR+
Sbjct: 357 LRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRRE 416
Query: 168 R 168
R
Sbjct: 417 R 417
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 46.2 bits (108), Expect = 5e-05
Identities = 47/206 (22%), Positives = 92/206 (44%), Gaps = 34/206 (16%)
Query: 107 DYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERR 166
D ++ +K++++ER+ +RE ER++E EERE++R RR + + +++ +RERR
Sbjct: 242 DRDERLKKEKQERE-EREKEREREREERERKR----------RREEEEREKERARDRERR 290
Query: 167 KRSMGGAAIAPPTSLVEKDKELPRDFPYEED-----------SRPRSQSSKAAIPPPVYE 215
KRS + + TS D+ R ++ R RS+S +
Sbjct: 291 KRSRSRSRHSSRTS----DRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
Query: 216 EQDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGG 275
+DR RS + S+ H+ + ++ + K ++G S K+ R
Sbjct: 347 SRDRRRSKSRDRKSY--------KHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
Query: 276 KIIVGDATEKDASKKSDSNPLTEILK 301
+ + K++ K++ N +E +K
Sbjct: 399 QSEDTNTESKESDTKNEVNGTSEDIK 424
Score = 33.9 bits (76), Expect = 0.27
Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 17/115 (14%)
Query: 108 YEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRK 167
Y K+ E +++ R+ + + +ER K+ K E R E E+ ER+RR+
Sbjct: 220 YAKIKATVEELKEKLRKRTEEPDRDERLKKEKQERE-----EREKEREREREERERKRRR 274
Query: 168 RSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRS 222
E++KE RD + SR RS+ S +D RS
Sbjct: 275 EE------------EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 46.2 bits (108), Expect = 5e-05
Identities = 47/206 (22%), Positives = 92/206 (44%), Gaps = 34/206 (16%)
Query: 107 DYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERR 166
D ++ +K++++ER+ +RE ER++E EERE++R RR + + +++ +RERR
Sbjct: 242 DRDERLKKEKQERE-EREKEREREREERERKR----------RREEEEREKERARDRERR 290
Query: 167 KRSMGGAAIAPPTSLVEKDKELPRDFPYEED-----------SRPRSQSSKAAIPPPVYE 215
KRS + + TS D+ R ++ R RS+S +
Sbjct: 291 KRSRSRSRHSSRTS----DRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
Query: 216 EQDRPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGG 275
+DR RS + S+ H+ + ++ + K ++G S K+ R
Sbjct: 347 SRDRRRSKSRDRKSY--------KHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREK 398
Query: 276 KIIVGDATEKDASKKSDSNPLTEILK 301
+ + K++ K++ N +E +K
Sbjct: 399 QSEDTNTESKESDTKNEVNGTSEDIK 424
Score = 33.9 bits (76), Expect = 0.27
Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 17/115 (14%)
Query: 108 YEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRK 167
Y K+ E +++ R+ + + +ER K+ K E R E E+ ER+RR+
Sbjct: 220 YAKIKATVEELKEKLRKRTEEPDRDERLKKEKQERE-----EREKEREREREERERKRRR 274
Query: 168 RSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRS 222
E++KE RD + SR RS+ S +D RS
Sbjct: 275 EE------------EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
>gi|28467003 kinase interacting stathmin [Homo sapiens]
Length = 419
Score = 45.4 bits (106), Expect = 9e-05
Identities = 31/104 (29%), Positives = 53/104 (50%), Gaps = 11/104 (10%)
Query: 296 LTEILKCPTKVVLLRNMVGAGEVD-----EDLEVETKEECEKYGKVGKCVI-FEIPGAPD 349
+ +++ PT V+ L N++ ++ ED+ + KEEC+KYG V ++ E PG
Sbjct: 312 IEDLVMLPTPVLRLLNVLDDDYLENEEEYEDVVEDVKEECQKYGPVVSLLVPKENPGRG- 370
Query: 350 DEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFR 393
++F+E+ + A L GR F G+ V A FY L ++
Sbjct: 371 ----QVFVEYANAGDSKAAQKLLTGRMFDGKFVVATFYPLSAYK 410
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/106 (28%), Positives = 57/106 (53%), Gaps = 17/106 (16%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
++ ++R+R+ER+RQ LERQ+ +E +E R +R E R+ + + E ERER++R
Sbjct: 188 QEQLERERQERERQERLERQERLERQE--RLERQERLDRERQERQERERLERLERERQER 245
Query: 169 SMGGAAIAPPTSLVEKDKELPRD-FPYEEDSRPRSQSSKAAIPPPV 213
E+ ++L R+ +E + R S ++ A++ P+
Sbjct: 246 --------------ERQEQLEREQLEWERERRISSAAAPASVETPL 277
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/60 (40%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Query: 110 KVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFAR-RPDPDSDEDEDYERERRKR 168
++ +RQ +E+QRQ+ELER++ ERE+ ++R E R R + + E E ERER++R
Sbjct: 141 EIQRRQLQEQQRQKELERERL--ERERMERERLERERLERERLERERLEQEQLERERQER 198
Score = 36.2 bits (82), Expect = 0.054
Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E++ +++R ERQ + + ERQ E +ERE+ + E R+ + ++ E +ERERR
Sbjct: 208 ERLERQERLERQERLDRERQ-ERQERERLERLERERQERERQEQLEREQLE-WERERRIS 265
Query: 169 SMGG-AAIAPPTSLVEKDKELPR------DFPYEEDSRPRSQSSKAAIPPPVYEEQDRPR 221
S A++ P + V D P E S+ A PPP P
Sbjct: 266 SAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPP-------PP 318
Query: 222 SPTGPSNSFLA 232
P GP+ + +A
Sbjct: 319 LPPGPAQASVA 329
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 45.1 bits (105), Expect = 1e-04
Identities = 30/106 (28%), Positives = 57/106 (53%), Gaps = 17/106 (16%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
++ ++R+R+ER+RQ LERQ+ +E +E R +R E R+ + + E ERER++R
Sbjct: 188 QEQLERERQERERQERLERQERLERQE--RLERQERLDRERQERQERERLERLERERQER 245
Query: 169 SMGGAAIAPPTSLVEKDKELPRD-FPYEEDSRPRSQSSKAAIPPPV 213
E+ ++L R+ +E + R S ++ A++ P+
Sbjct: 246 --------------ERQEQLEREQLEWERERRISSAAAPASVETPL 277
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/60 (40%), Positives = 39/60 (65%), Gaps = 3/60 (5%)
Query: 110 KVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFAR-RPDPDSDEDEDYERERRKR 168
++ +RQ +E+QRQ+ELER++ ERE+ ++R E R R + + E E ERER++R
Sbjct: 141 EIQRRQLQEQQRQKELERERL--ERERMERERLERERLERERLERERLEQEQLERERQER 198
Score = 36.2 bits (82), Expect = 0.054
Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 16/131 (12%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E++ +++R ERQ + + ERQ E +ERE+ + E R+ + ++ E +ERERR
Sbjct: 208 ERLERQERLERQERLDRERQ-ERQERERLERLERERQERERQEQLEREQLE-WERERRIS 265
Query: 169 SMGG-AAIAPPTSLVEKDKELPR------DFPYEEDSRPRSQSSKAAIPPPVYEEQDRPR 221
S A++ P + V D P E S+ A PPP P
Sbjct: 266 SAAAPASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPP-------PP 318
Query: 222 SPTGPSNSFLA 232
P GP+ + +A
Sbjct: 319 LPPGPAQASVA 329
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 43.9 bits (102), Expect = 3e-04
Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 11/117 (9%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRK--DRHEA---SGFARRPDPDSDEDEDYER 163
E +R+RE+ + R L R++E EE+E+RR+ DR EA SG + + D++ +R
Sbjct: 326 ELEARRRREQEEELRRL-REQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKR 384
Query: 164 ERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRP 220
R+ R G P +S E + EL R+ + +P+S S++ A P E++ RP
Sbjct: 385 GRKGRGRG----PPSSSDSEPEAELERE-AKKSAKKPQSSSTEPARKPGQKEKRVRP 436
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 43.9 bits (102), Expect = 3e-04
Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 11/117 (9%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRK--DRHEA---SGFARRPDPDSDEDEDYER 163
E +R+RE+ + R L R++E EE+E+RR+ DR EA SG + + D++ +R
Sbjct: 326 ELEARRRREQEEELRRL-REQEKEEKERRRERADRGEAERGSGGSSGDELREDDEPVKKR 384
Query: 164 ERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRP 220
R+ R G P +S E + EL R+ + +P+S S++ A P E++ RP
Sbjct: 385 GRKGRGRG----PPSSSDSEPEAELERE-AKKSAKKPQSSSTEPARKPGQKEKRVRP 436
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/53 (41%), Positives = 33/53 (62%)
Query: 116 REERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
R+E +++RE ER+KE EREKR+++R + R E + ERER+KR
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKR 100
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/98 (26%), Positives = 51/98 (52%), Gaps = 4/98 (4%)
Query: 110 KVVKRQREERQRQRELERQKEIEEREKR-RKDRHEASGFARRPDPDSDEDEDYERERRKR 168
K +R+RE+R+R+RE ER++E ++EK+ + + E RR + ++ E E+ E+ ++K
Sbjct: 60 KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE 119
Query: 169 SMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSK 206
+ E+ +E R+ E R R + +
Sbjct: 120 KKERGRTSKEGKERERKEERKRE---ERKERERKKEER 154
Score = 38.9 bits (89), Expect = 0.008
Identities = 17/56 (30%), Positives = 34/56 (60%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
+ ++EER+R+ ER+++ EEREK R+ + ++ +E ++ ER+ RK+
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKK 188
Score = 38.1 bits (87), Expect = 0.014
Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 7/60 (11%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ +R+REER +E ER+KE E+E+ RK+R + R E+E E+ER++R
Sbjct: 134 ERKEERKREER---KERERKKEEREKERERKERKK----RERKQVGEKEEERKEKERKER 186
Score = 37.7 bits (86), Expect = 0.019
Identities = 19/61 (31%), Positives = 40/61 (65%), Gaps = 5/61 (8%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ + +R+ER+R++E ER+KE E +E+++++R + + + E E ER++R+R
Sbjct: 137 EERKREERKERERKKE-EREKERERKERKKRERKQVG----EKEEERKEKERKERKKRER 191
Query: 169 S 169
+
Sbjct: 192 N 192
Score = 37.0 bits (84), Expect = 0.032
Identities = 27/117 (23%), Positives = 53/117 (45%), Gaps = 16/117 (13%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ +R+RE +++++ ER+KE ER+KRR+++ G E+++ +++ K+
Sbjct: 72 EREKERKRERGKKEKKGERKKEERERKKRRREKENKEG----------EEKEKRKKKEKK 121
Query: 169 SMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTG 225
G TS K++E + EE + + E + R R G
Sbjct: 122 ERG------RTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172
Score = 36.6 bits (83), Expect = 0.041
Identities = 13/56 (23%), Positives = 39/56 (69%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
+++R++R+R++ E+++E +E+E++ + + E + R+ + + E + ++ER+K+
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
Score = 35.4 bits (80), Expect = 0.092
Identities = 22/57 (38%), Positives = 34/57 (59%), Gaps = 7/57 (12%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDY-ERERRKR 168
KR+R ++R++E ER KE ER+K RK + E R+ + D ++ E+ER KR
Sbjct: 188 KRERNRKERKKERER-KERRERKKERKKKEE-----RKKERQKDRQTNWREKERGKR 238
Score = 34.7 bits (78), Expect = 0.16
Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 6/60 (10%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ K +++ER+R+ ER+KE +++E+R+K+R + R E E +RER++R
Sbjct: 190 ERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWR------EKERGKRERKER 243
Score = 34.3 bits (77), Expect = 0.21
Identities = 15/59 (25%), Positives = 33/59 (55%)
Query: 110 KVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
K +R++E +++R+ +K++ E+E+ RK++ R + + E +ERR+R
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRER 208
Score = 34.3 bits (77), Expect = 0.21
Identities = 16/60 (26%), Positives = 32/60 (53%)
Query: 110 KVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRS 169
K V + EER+ + ER+K R++R+K+R R+ + E+ ER++ +++
Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228
Score = 30.8 bits (68), Expect = 2.3
Identities = 14/60 (23%), Positives = 35/60 (58%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
+K ++Q E++ +R+ + +KE ++RE+ RK+R + R + + + ER++ ++
Sbjct: 164 KKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQ 223
Score = 30.4 bits (67), Expect = 3.0
Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 26/104 (25%)
Query: 109 EKVVKRQREERQR------QRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYE 162
EK K++++ER R +RE + +++ EER++R + + E E E E
Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER----------EKERERKE 162
Query: 163 RERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSK 206
R++R+R G EK++E E R R++ +
Sbjct: 163 RKKRERKQVG----------EKEEERKEKERKERKKRERNRKER 196
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 43.1 bits (100), Expect = 4e-04
Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 8/106 (7%)
Query: 123 RELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER-----RKRSMGGAAIAP 177
RE ERQ+E E + KR K+RH D D D ER+R RKR G
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 178 PTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPP--PVYEEQDRPR 221
+ ++++E RD E+D R R + + I + E+DR R
Sbjct: 118 TETERQEERERQRDRKREKD-RERQRQREIGIDKDREIETEKDRDR 162
Score = 42.4 bits (98), Expect = 8e-04
Identities = 25/63 (39%), Positives = 39/63 (61%), Gaps = 2/63 (3%)
Query: 107 DYEKVVKRQREERQ-RQRELERQKEIEEREK-RRKDRHEASGFARRPDPDSDEDEDYERE 164
D E+ ++QRE R+ R RE +R+KE ER++ R+K+R + R D D++ D ER+
Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQ 233
Query: 165 RRK 167
R K
Sbjct: 234 REK 236
Score = 36.6 bits (83), Expect = 0.041
Identities = 26/109 (23%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Query: 114 RQRE-ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGG 172
R RE E +RQ E ERQ++ + + R + R G + + ++++D D ERE +
Sbjct: 114 RDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR 173
Query: 173 AAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPR 221
E ++ R+ E++ R R + + Y E++ R
Sbjct: 174 DRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGR 222
Score = 35.0 bits (79), Expect = 0.12
Identities = 32/115 (27%), Positives = 52/115 (45%), Gaps = 40/115 (34%)
Query: 113 KRQRE-ERQRQRE--LERQKEIE----------------------EREKRRKDRHEASGF 147
KR+++ ERQRQRE +++ +EIE ER+K+R+ R +
Sbjct: 133 KREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRE 192
Query: 148 ARRPDPDSDEDEDYERER-----RKRSMGGAAIAPPTSLVEKDKELPRDFPYEED 197
+R D + D D ++ER R+R G ++DKE R+ E+D
Sbjct: 193 RQREKEDRERDRDRQKEREKDRYRERETGR----------DRDKERDRERQREKD 237
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 43.1 bits (100), Expect = 4e-04
Identities = 22/61 (36%), Positives = 39/61 (63%), Gaps = 2/61 (3%)
Query: 110 KVVKRQREERQRQRELERQKEIEEREKRRKDRHE--ASGFARRPDPDSDEDEDYERERRK 167
K +R+RE+R+R+RE ER++E ++EK+++ + E +R + + E E+ERRK
Sbjct: 37 KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRK 96
Query: 168 R 168
R
Sbjct: 97 R 97
Score = 40.0 bits (92), Expect = 0.004
Identities = 19/60 (31%), Positives = 36/60 (60%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ K +++ ++R+R ER+++ +EREK+RK+R E R+ + E + R RK+
Sbjct: 57 ERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKK 116
Score = 39.7 bits (91), Expect = 0.005
Identities = 17/56 (30%), Positives = 36/56 (64%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
++QR+ER+ + +R+KE ++RE++++ R E R + + + + ER+R+KR
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138
Score = 37.4 bits (85), Expect = 0.024
Identities = 16/60 (26%), Positives = 35/60 (58%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
E+ KR+ E+QR+ E+++ ++EK++++R + R+ + E E ++RR+R
Sbjct: 74 ERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133
Score = 37.4 bits (85), Expect = 0.024
Identities = 16/55 (29%), Positives = 31/55 (56%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRK 167
++++ ++R+RE ER K +R+KR+K+ E R + + + RER+K
Sbjct: 139 RKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKK 193
Score = 36.6 bits (83), Expect = 0.041
Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 110 KVVKRQREERQR-QRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
K K++RE +QR +RE +++KE +ERE+ K R E RR E E+ER KR
Sbjct: 98 KKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE-RKREKERGKR 156
Score = 35.8 bits (81), Expect = 0.071
Identities = 18/57 (31%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYER-ERRKR 168
+++R +++R++E +R+KE +RE++RK R + +R + ++ ER ERR+R
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRER 191
Score = 35.0 bits (79), Expect = 0.12
Identities = 16/52 (30%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDED 160
E+ KR+R ++R++E ER++ E +++R+K+R + R+ D +D D
Sbjct: 167 EREKKRERNRKERKKERERKERRERKKERKKERRKKK--ERKKDRKTDRQTD 216
Score = 34.3 bits (77), Expect = 0.21
Identities = 16/55 (29%), Positives = 35/55 (63%), Gaps = 5/55 (9%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRK 167
KR++E +R+R+ +++K+ E +KR ++R E R+ + + E + ++ER+K
Sbjct: 148 KREKERGKRERKRKKRKKEEREKKRERNRKE-----RKKERERKERRERKKERKK 197
Score = 33.5 bits (75), Expect = 0.35
Identities = 23/63 (36%), Positives = 39/63 (61%), Gaps = 7/63 (11%)
Query: 113 KRQRE-ERQRQR---ELERQKEIE---EREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
KR+RE ER+R+R E +++K+ E ERE++RK+R + R + + E +RER
Sbjct: 47 KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRER 106
Query: 166 RKR 168
++R
Sbjct: 107 KQR 109
Score = 33.5 bits (75), Expect = 0.35
Identities = 19/65 (29%), Positives = 39/65 (60%), Gaps = 5/65 (7%)
Query: 109 EKVVKRQREERQRQRELERQKEIEER--EKRRKDR---HEASGFARRPDPDSDEDEDYER 163
E+ K++R+ER+R+ + R+++ ++R +KRRK+R E R+ E+ + +R
Sbjct: 113 ERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKR 172
Query: 164 ERRKR 168
ER ++
Sbjct: 173 ERNRK 177
Score = 33.1 bits (74), Expect = 0.46
Identities = 16/36 (44%), Positives = 28/36 (77%), Gaps = 1/36 (2%)
Query: 106 NDYEKVVKRQREERQRQRELERQKEIEEREKRRKDR 141
N E+ +R+R+ER R+R+ ER+KE ++++R+KDR
Sbjct: 175 NRKERKKERERKER-RERKKERKKERRKKKERKKDR 209
Score = 32.7 bits (73), Expect = 0.60
Identities = 16/55 (29%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 113 KRQREERQRQREL---ERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERE 164
KR++EER+++RE ER+KE E +E+R + + ++ + D D + +
Sbjct: 162 KRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTD 216
Score = 32.3 bits (72), Expect = 0.78
Identities = 16/60 (26%), Positives = 35/60 (58%)
Query: 109 EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
+K ++QR R+R+++ ER++ E ++RR+ + + +R E E +RER+++
Sbjct: 102 KKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK 161
Score = 32.3 bits (72), Expect = 0.78
Identities = 13/57 (22%), Positives = 33/57 (57%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRS 169
KR+R+ ++R++E +K R++R+K+R R+ + + + ER++ +++
Sbjct: 155 KRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKT 211
Score = 32.0 bits (71), Expect = 1.0
Identities = 15/54 (27%), Positives = 28/54 (51%)
Query: 115 QREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKR 168
QRE +++ ER+K EREK RK +R + ++ + +R+ R++
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Score = 31.6 bits (70), Expect = 1.3
Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 7/67 (10%)
Query: 109 EKVVKRQR-EERQRQR-ELERQ-KEIEEREKRR----KDRHEASGFARRPDPDSDEDEDY 161
+K KR+R +ER+R+R E E+Q KE E+E+R+ K + E RR E ++
Sbjct: 64 KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123
Query: 162 ERERRKR 168
ERE ++R
Sbjct: 124 ERENKQR 130
Score = 31.2 bits (69), Expect = 1.7
Identities = 23/94 (24%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGG 172
+R+R++++ ++E ER+ + + RE++RK R + R+ E ER+R+KR
Sbjct: 111 RRERKKKKERKERERENK-QRRERKRKKRRKKK--RRKERKREKERGKRERKRKKRKKEE 167
Query: 173 AAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSK 206
+ E+ KE R E + + K
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRK 201
Score = 31.2 bits (69), Expect = 1.7
Identities = 12/33 (36%), Positives = 24/33 (72%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEAS 145
+++R ER+++R+ ER+K+ E ++ R+ DR S
Sbjct: 185 RKERRERKKERKKERRKKKERKKDRKTDRQTDS 217
Score = 30.0 bits (66), Expect = 3.9
Identities = 18/94 (19%), Positives = 45/94 (47%), Gaps = 1/94 (1%)
Query: 113 KRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERERRKRSMGG 172
KR++E+++R+R+ ++E +++K RK+R + R + +ER++ G
Sbjct: 96 KRKKEKKKRERKQRGRRE-RKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154
Query: 173 AAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSK 206
++++E R+ +E + R + +
Sbjct: 155 KRERKRKKRKKEEREKKRERNRKERKKERERKER 188
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 109 EKVVKRQRE---ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
++ ++R+RE ER+R+RE +R++E E +R K+R + R + + + + E+
Sbjct: 230 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 289
Query: 166 RKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQ 203
R++ + A P+ L + R EE +P Q
Sbjct: 290 REKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQ 327
Score = 32.0 bits (71), Expect = 1.0
Identities = 18/53 (33%), Positives = 33/53 (62%), Gaps = 8/53 (15%)
Query: 107 DYEKVVKRQRE-------ERQRQRELERQKEIE-EREKRRKDRHEASGFARRP 151
D E+ +R+RE E++R+RE ER++E+E +RE+R +++ + A P
Sbjct: 250 DREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEP 302
Score = 28.9 bits (63), Expect = 8.6
Identities = 69/288 (23%), Positives = 102/288 (35%), Gaps = 72/288 (25%)
Query: 40 AKSQRTKQSTVLAPVI--DLKRGGSSDDRQI------VDTPPHVAAGLKD-----PVPSG 86
A +R K S L P LK G + + V TP H L +PS
Sbjct: 317 ATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSS 376
Query: 87 FSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASG 146
+A +LI N+ EK + RQR R RQ + +RQ ++ E ++ ++H G
Sbjct: 377 SAATALLIQRT--------NEEEKWLARQR--RLRQEKEDRQSQVSEFRQQVLEQHLDMG 426
Query: 147 FARRPDPDSDEDEDYERER---RKRSMGG------------------------AAIAPPT 179
R P P E R + GG A+ P
Sbjct: 427 --RPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPV 484
Query: 180 SLVEKDKELPRDFPYEEDSRPRS--QSSKAAIP---------PPVYEEQDRPRSPTGPSN 228
SL++ E R + S P + S +AA+P P EE R R P P +
Sbjct: 485 SLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREP-APLD 543
Query: 229 SFL-----ANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTS 271
+ GG++ H Q + G L + E+ T L ++ S
Sbjct: 544 KYQPPPPPPREGGSLEH---QPFLPGPGPFLAELEKSTQTILGQQRAS 588
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/98 (25%), Positives = 49/98 (50%), Gaps = 3/98 (3%)
Query: 109 EKVVKRQRE---ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
++ ++R+RE ER+R+RE +R++E E +R K+R + R + + + + E+
Sbjct: 334 DEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRA 393
Query: 166 RKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQ 203
R++ + A P+ L + R EE +P Q
Sbjct: 394 REKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQ 431
Score = 32.0 bits (71), Expect = 1.0
Identities = 18/53 (33%), Positives = 33/53 (62%), Gaps = 8/53 (15%)
Query: 107 DYEKVVKRQRE-------ERQRQRELERQKEIE-EREKRRKDRHEASGFARRP 151
D E+ +R+RE E++R+RE ER++E+E +RE+R +++ + A P
Sbjct: 354 DREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEP 406
Score = 28.9 bits (63), Expect = 8.6
Identities = 69/288 (23%), Positives = 102/288 (35%), Gaps = 72/288 (25%)
Query: 40 AKSQRTKQSTVLAPVI--DLKRGGSSDDRQI------VDTPPHVAAGLKD-----PVPSG 86
A +R K S L P LK G + + V TP H L +PS
Sbjct: 421 ATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSS 480
Query: 87 FSAGEVLIPLADEYDPMFPNDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASG 146
+A +LI N+ EK + RQR R RQ + +RQ ++ E ++ ++H G
Sbjct: 481 SAATALLIQRT--------NEEEKWLARQR--RLRQEKEDRQSQVSEFRQQVLEQHLDMG 530
Query: 147 FARRPDPDSDEDEDYERER---RKRSMGG------------------------AAIAPPT 179
R P P E R + GG A+ P
Sbjct: 531 --RPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPV 588
Query: 180 SLVEKDKELPRDFPYEEDSRPRS--QSSKAAIP---------PPVYEEQDRPRSPTGPSN 228
SL++ E R + S P + S +AA+P P EE R R P P +
Sbjct: 589 SLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREP-APLD 647
Query: 229 SFL-----ANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTS 271
+ GG++ H Q + G L + E+ T L ++ S
Sbjct: 648 KYQPPPPPPREGGSLEH---QPFLPGPGPFLAELEKSTQTILGQQRAS 692
>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
isoform 1 [Homo sapiens]
Length = 483
Score = 42.7 bits (99), Expect = 6e-04
Identities = 28/112 (25%), Positives = 58/112 (51%), Gaps = 7/112 (6%)
Query: 107 DY-EKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYERER 165
DY E+ + +R++ + RE ER K EE +R+K+R+E +R + + +++D R++
Sbjct: 344 DYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDK 403
Query: 166 RKRSMGGAAIA------PPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPP 211
K++ +I +V++D+ +D P + +P ++S PP
Sbjct: 404 GKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPP 455
Score = 39.7 bits (91), Expect = 0.005
Identities = 22/48 (45%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 113 KRQRE-ERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDE 159
+R+RE ER+RQRE ER+K EE +++RKD + R P+ D +DE
Sbjct: 218 RRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDE 265
Score = 28.9 bits (63), Expect = 8.6
Identities = 13/52 (25%), Positives = 30/52 (57%)
Query: 112 VKRQREERQRQRELERQKEIEEREKRRKDRHEASGFARRPDPDSDEDEDYER 163
+K ++ R+ +RE R++EIE + +R ++R + +R D ++ + +R
Sbjct: 204 LKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDR 255
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,605,364
Number of Sequences: 37866
Number of extensions: 859140
Number of successful extensions: 10330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 286
Number of HSP's successfully gapped in prelim test: 370
Number of HSP's that attempted gapping in prelim test: 5001
Number of HSP's gapped (non-prelim): 3176
length of query: 401
length of database: 18,247,518
effective HSP length: 104
effective length of query: 297
effective length of database: 14,309,454
effective search space: 4249907838
effective search space used: 4249907838
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.