Guide to the Human Genome
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Search of human proteins with 14249388

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
         (184 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap...   384   e-107
gi|126116581 retina and anterior neural fold homeobox [Homo sapi...   179   9e-46
gi|24497589 aristaless related homeobox [Homo sapiens]                118   3e-27
gi|55743092 aristaless-like homeobox 4 [Homo sapiens]                 108   3e-24
gi|46249382 paired-like homeobox 2a [Homo sapiens]                    108   3e-24
gi|57232759 intestine-specific homeobox [Homo sapiens]                105   2e-23
gi|7706659 paired related homeobox 2 [Homo sapiens]                   105   3e-23
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                103   6e-23
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho...   103   6e-23
gi|12707580 paired-like homeobox 2b [Homo sapiens]                    102   1e-22
gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]         101   4e-22
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]   101   4e-22
gi|34365783 visual system homeobox 2 [Homo sapiens]                   100   7e-22
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi...   100   7e-22
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]                 99   2e-21
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]                  99   2e-21
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]                  99   2e-21
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]                  99   2e-21
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]                  99   2e-21
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]                   99   2e-21
gi|122937321 UNC homeobox [Homo sapiens]                               99   3e-21
gi|189083681 paired box gene 6 isoform a [Homo sapiens]                98   5e-21
gi|4580424 paired box gene 6 isoform b [Homo sapiens]                  98   5e-21
gi|4505615 paired box gene 6 isoform a [Homo sapiens]                  98   5e-21
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]             97   6e-21
gi|14149760 orthopedia homeobox [Homo sapiens]                         97   6e-21
gi|122937484 dorsal root ganglia homeobox [Homo sapiens]               97   8e-21
gi|4505619 paired box 7 isoform 1 [Homo sapiens]                       96   1e-20
gi|7524359 paired box 7 isoform 2 [Homo sapiens]                       96   1e-20
gi|207029223 paired box 7 isoform 3 [Homo sapiens]                     96   1e-20

>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
           sapiens]
          Length = 184

 Score =  384 bits (987), Expect = e-107
 Identities = 184/184 (100%), Positives = 184/184 (100%)

Query: 1   MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREEL 60
           MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREEL
Sbjct: 1   MFLSPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREEL 60

Query: 61  AAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEP 120
           AAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEP
Sbjct: 61  AAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEP 120

Query: 121 WLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRA 180
           WLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRA
Sbjct: 121 WLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKEHAQALDRA 180

Query: 181 WPPA 184
           WPPA
Sbjct: 181 WPPA 184


>gi|126116581 retina and anterior neural fold homeobox [Homo
           sapiens]
          Length = 346

 Score =  179 bits (455), Expect = 9e-46
 Identities = 116/243 (47%), Positives = 133/243 (54%), Gaps = 71/243 (29%)

Query: 5   PGEGPATEGGGLGPG--------EEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYS 56
           PGE   + G  +GP         EE PKKKHRRNRTTFTTYQLH+LERAFE SHYPDVYS
Sbjct: 106 PGEARPSPGLPVGPATGEAKLSEEEQPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYS 165

Query: 57  REELAAKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAM-- 114
           REELA KV+LPEVRVQVWFQNRRAKWRRQE+LE     V++ +L ++P L F+R P    
Sbjct: 166 REELAGKVNLPEVRVQVWFQNRRAKWRRQEKLE-----VSSMKLQDSPLLSFSRSPPSAT 220

Query: 115 -----------------SLPLEPWLGP----------------GPPA----------VPG 131
                            +LPLE WLGP                GPPA           P 
Sbjct: 221 LSPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPP 280

Query: 132 LPRLLGP--GPGLQASFGP---HAFAPTFADGFALEE--------ASLRLLAKEHAQALD 178
            P L  P  GPGLQ    P   +   P F D F L+E        A+LRL AKEH QA+ 
Sbjct: 281 PPFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAALRLKAKEHIQAIG 340

Query: 179 RAW 181
           + W
Sbjct: 341 KPW 343


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score =  118 bits (295), Expect = 3e-27
 Identities = 65/129 (50%), Positives = 81/129 (62%), Gaps = 11/129 (8%)

Query: 6   GEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVH 65
           GE       G    E   K+K RR RTTFT+YQL +LERAF+ +HYPDV++REELA ++ 
Sbjct: 307 GEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLD 366

Query: 66  LPEVRVQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWL--G 123
           L E RVQVWFQNRRAKWR++E+    +GA   P     P LPF  P + + PL P+L   
Sbjct: 367 LTEARVQVWFQNRRAKWRKREK----AGAQTHP-----PGLPFPGPLSATHPLSPYLDAS 417

Query: 124 PGPPAVPGL 132
           P PP  P L
Sbjct: 418 PFPPHHPAL 426


>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
          Length = 411

 Score =  108 bits (270), Expect = 3e-24
 Identities = 61/135 (45%), Positives = 77/135 (57%), Gaps = 5/135 (3%)

Query: 21  EAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRA 80
           E+ K K RRNRTTFT+YQL +LE+ F+ +HYPDVY+RE+LA +  L E RVQVWFQNRRA
Sbjct: 208 ESNKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWFQNRRA 267

Query: 81  KWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLE--PWLGPGPPAVPGLPRLLGP 138
           KWR++ER   G           A  LP          ++   WLG    A P +P  + P
Sbjct: 268 KWRKRERF--GQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWLGNNGAASP-VPACVVP 324

Query: 139 GPGLQASFGPHAFAP 153
              + A   PHA  P
Sbjct: 325 CDPVPACMSPHAHPP 339



 Score = 28.9 bits (63), Expect = 2.6
 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 1/46 (2%)

Query: 88  LESGSGAVAA-PRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGL 132
           LESG+GA  +  +    P+ P  +PP    P +    P PPA P L
Sbjct: 77  LESGAGARGSFNKFQPQPSTPQPQPPPQPQPQQQQPQPQPPAQPHL 122


>gi|46249382 paired-like homeobox 2a [Homo sapiens]
          Length = 284

 Score =  108 bits (269), Expect = 3e-24
 Identities = 66/149 (44%), Positives = 75/149 (50%), Gaps = 39/149 (26%)

Query: 24  KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
           K+K RR RTTFT+ QL +LER F  +HYPD+Y+REELA K+ L E RVQVWFQNRRAK+R
Sbjct: 87  KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146

Query: 84  RQERLESGSGAVAA-----------------------------PRLPEAPALPFARPPAM 114
           +QER  S  GA  A                               LP  PA   A P   
Sbjct: 147 KQERAASAKGAAGAAGAKKGEARCSSEDDDSKESTCSPTPDSTASLPPPPAPGLASPRLS 206

Query: 115 SLPLEPWLGPGPPAVPGLPRLLGPGPGLQ 143
             PL   LG GP          GPGPG Q
Sbjct: 207 PSPLPVALGSGP----------GPGPGPQ 225


>gi|57232759 intestine-specific homeobox [Homo sapiens]
          Length = 245

 Score =  105 bits (262), Expect = 2e-23
 Identities = 57/108 (52%), Positives = 76/108 (70%), Gaps = 9/108 (8%)

Query: 5   PGEGPATEGGGLGPGEEAP---KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELA 61
           PGE  A+  G   P ++ P   +K  RR RTTFTT QLH+LE+ F  +HYPDV+ R +LA
Sbjct: 57  PGEAAASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLA 116

Query: 62  AKVHLPEVRVQVWFQNRRAKWRRQERLESGSGAVAAP-RLPEAP-ALP 107
           A+++LPE RVQ+WFQN+RAKWR+QE++    G + AP +L EA  ALP
Sbjct: 117 ARINLPEARVQIWFQNQRAKWRKQEKI----GNLGAPQQLSEASVALP 160


>gi|7706659 paired related homeobox 2 [Homo sapiens]
          Length = 253

 Score =  105 bits (261), Expect = 3e-23
 Identities = 78/176 (44%), Positives = 89/176 (50%), Gaps = 32/176 (18%)

Query: 4   SPGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAK 63
           SPG G A +           KKK RRNRTTF + QL  LER FE +HYPD + REELA +
Sbjct: 91  SPGRGSAAKR----------KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARR 140

Query: 64  VHLPEVRVQVWFQNRRAKWRRQER--LESGSGAVAAPRLPEA----PALPFARPPAMSLP 117
           V+L E RVQVWFQNRRAK+RR ER  L S S ++      EA    P  P  RP A+S  
Sbjct: 141 VNLSEARVQVWFQNRRAKFRRNERAMLASRSASLLKSYSQEAAIEQPVAP--RPTALSPD 198

Query: 118 LEPWLGPGP-PAVPGLPRLLGPGPGLQASFGPHAFAPTFADGFALEEASLRLLAKE 172
              W    P   VP         P    S GP       A+      ASLRL AKE
Sbjct: 199 YLSWTASSPYSTVP---------PYSPGSSGPATPGVNMANSI----ASLRLKAKE 241


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score =  103 bits (258), Expect = 6e-23
 Identities = 57/119 (47%), Positives = 72/119 (60%), Gaps = 9/119 (7%)

Query: 24  KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
           K K RRNRTTF+T+QL +LE+ F+ +HYPDVY+RE+LA +  L E RVQVWFQNRRAKWR
Sbjct: 150 KSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWR 209

Query: 84  RQERLESGSGAVAAPRLPEAPALPFARPPAM----SLPLEPWLGPGPPAVPGLPRLLGP 138
           ++ER     G +   R P   A   +  P       L    W  PG  + PG P L+ P
Sbjct: 210 KRERY----GKIQEGRNPFTAAYDISVLPRTDSHPQLQNSLWASPGSGS-PGGPCLVSP 263


>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
           sapiens]
          Length = 406

 Score =  103 bits (258), Expect = 6e-23
 Identities = 64/162 (39%), Positives = 80/162 (49%), Gaps = 39/162 (24%)

Query: 5   PGEGPATEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKV 64
           P EGP T  G        P ++ RR RT FT +QL +LE  F+ S YPDV +RE LAA++
Sbjct: 123 PAEGPQTAEG------PQPPERKRRRRTAFTQFQLQELENFFDESQYPDVVARERLAARL 176

Query: 65  HLPEVRVQVWFQNRRAKWRRQER-----------------LESGSGAVAA---------- 97
           +L E RVQVWFQNRRAKW+R +R                 +  G    AA          
Sbjct: 177 NLTEDRVQVWFQNRRAKWKRNQRVLMLRNTATADLAHPLDMFLGGAYYAAPALDPALCVH 236

Query: 98  --PRLPEAPALPF----ARPPAMSLPLEPWLGPGPPAVPGLP 133
             P+LP  P LP      RPP + +P  P + P PP  P  P
Sbjct: 237 LVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIAPMPPMAPVPP 278



 Score = 30.0 bits (66), Expect = 1.2
 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 9/59 (15%)

Query: 99  RLPEAPALPFAR----PPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGLQASFGPHAFAP 153
           R+P  P  P AR    PP   LP  P + P PP  P  P  L PGP + A   P +  P
Sbjct: 329 RVPPGP--PMARVPPGPPMAPLPPGPPMAPLPPGPPMAP--LPPGPPM-APLPPRSHVP 382



 Score = 27.7 bits (60), Expect = 5.8
 Identities = 20/50 (40%), Positives = 21/50 (42%), Gaps = 5/50 (10%)

Query: 93  GAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAVPGLPRLLGPGPGL 142
           G   AP  P  P  P    P    P+ P L PGPP  P  PR   P  GL
Sbjct: 342 GPPMAPLPPGPPMAPLPPGP----PMAP-LPPGPPMAPLPPRSHVPHTGL 386


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score =  102 bits (255), Expect = 1e-22
 Identities = 73/194 (37%), Positives = 92/194 (47%), Gaps = 26/194 (13%)

Query: 11  TEGGGLGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           T+ GGL       K+K RR RTTFT+ QL +LER F  +HYPD+Y+REELA K+ L E R
Sbjct: 87  TDHGGLNE-----KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEAR 141

Query: 71  VQVWFQNRRAKWRRQERLESGSGAVA---APRLPEAPALPFARPPAMSLPLEPWLGPGP- 126
           VQVWFQNRRAK+R+QER  + + A A   +       +       A S   +   GPGP 
Sbjct: 142 VQVWFQNRRAKFRKQERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPN 201

Query: 127 ----------------PAVPGLPRLLGP-GPGLQASFGPHAFAPTFADGFALEEASLRLL 169
                           P+  G P   GP GPG +   G  A A   A   A   A+    
Sbjct: 202 PNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAG 261

Query: 170 AKEHAQALDRAWPP 183
               A    + W P
Sbjct: 262 GLAAAGGPGQGWAP 275


>gi|11056038 visual system homeobox 1 isoform a [Homo sapiens]
          Length = 365

 Score =  101 bits (251), Expect = 4e-22
 Identities = 45/73 (61%), Positives = 57/73 (78%)

Query: 24  KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
           K+K RR+RT FT +QL +LE+AF  +HYPDVY+RE LA K  LPE R+QVWFQNRRAKWR
Sbjct: 161 KRKKRRHRTVFTAHQLEELEKAFSEAHYPDVYAREMLAVKTELPEDRIQVWFQNRRAKWR 220

Query: 84  RQERLESGSGAVA 96
           ++E+   GS  +A
Sbjct: 221 KREKRWGGSSVMA 233


>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
          Length = 217

 Score =  101 bits (251), Expect = 4e-22
 Identities = 60/125 (48%), Positives = 69/125 (55%), Gaps = 15/125 (12%)

Query: 20  EEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRR 79
           EE  K+K RRNRTTF + QL  LER FE +HYPD + RE+LA +V+L E RVQVWFQNRR
Sbjct: 87  EEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRR 146

Query: 80  AKWRRQER----------LESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPAV 129
           AK+RR ER          L+S SG V A   P  P     RP         W    P   
Sbjct: 147 AKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVP-----RPAPRPTDYLSWGTASPYRS 201

Query: 130 PGLPR 134
             LPR
Sbjct: 202 SSLPR 206


>gi|34365783 visual system homeobox 2 [Homo sapiens]
          Length = 361

 Score =  100 bits (249), Expect = 7e-22
 Identities = 45/76 (59%), Positives = 58/76 (76%)

Query: 21  EAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRA 80
           +  K+K RR+RT FT+YQL +LE+AF  +HYPDVY+RE LA K  LPE R+QVWFQNRRA
Sbjct: 142 QTKKRKKRRHRTIFTSYQLEELEKAFNEAHYPDVYAREMLAMKTELPEDRIQVWFQNRRA 201

Query: 81  KWRRQERLESGSGAVA 96
           KWR++E+    S  +A
Sbjct: 202 KWRKREKCWGRSSVMA 217


>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
           sapiens]
          Length = 245

 Score =  100 bits (249), Expect = 7e-22
 Identities = 56/102 (54%), Positives = 65/102 (63%), Gaps = 11/102 (10%)

Query: 20  EEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRR 79
           EE  K+K RRNRTTF + QL  LER FE +HYPD + RE+LA +V+L E RVQVWFQNRR
Sbjct: 87  EEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRR 146

Query: 80  AKWRRQER----------LESGSGAVAAPRLPEAPALPFARP 111
           AK+RR ER          L+S SG V A   P  P  P  RP
Sbjct: 147 AKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPR-PAPRP 187


>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
          Length = 483

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 58/131 (44%), Positives = 72/131 (54%), Gaps = 16/131 (12%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LERAFE +HYPD+Y+REELA +  L E R
Sbjct: 202 EGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEAR 261

Query: 71  VQVWFQNRRAKWRRQ----------ERLESGSGAVAAPRLP-----EAPALPFARPPAMS 115
           VQVWF NRRA+WR+Q            +  G    A P LP     E    P + P A+S
Sbjct: 262 VQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVS 321

Query: 116 LPLEPWLGPGP 126
            P      P P
Sbjct: 322 DPSSTVHRPQP 332


>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
          Length = 403

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 58/131 (44%), Positives = 72/131 (54%), Gaps = 16/131 (12%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LERAFE +HYPD+Y+REELA +  L E R
Sbjct: 203 EGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEAR 262

Query: 71  VQVWFQNRRAKWRRQ----------ERLESGSGAVAAPRLP-----EAPALPFARPPAMS 115
           VQVWF NRRA+WR+Q            +  G    A P LP     E    P + P A+S
Sbjct: 263 VQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVS 322

Query: 116 LPLEPWLGPGP 126
            P      P P
Sbjct: 323 DPSSTVHRPQP 333


>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
          Length = 407

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 58/131 (44%), Positives = 72/131 (54%), Gaps = 16/131 (12%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LERAFE +HYPD+Y+REELA +  L E R
Sbjct: 203 EGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEAR 262

Query: 71  VQVWFQNRRAKWRRQ----------ERLESGSGAVAAPRLP-----EAPALPFARPPAMS 115
           VQVWF NRRA+WR+Q            +  G    A P LP     E    P + P A+S
Sbjct: 263 VQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVS 322

Query: 116 LPLEPWLGPGP 126
            P      P P
Sbjct: 323 DPSSTVHRPQP 333


>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
          Length = 505

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 58/131 (44%), Positives = 72/131 (54%), Gaps = 16/131 (12%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LERAFE +HYPD+Y+REELA +  L E R
Sbjct: 203 EGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEAR 262

Query: 71  VQVWFQNRRAKWRRQ----------ERLESGSGAVAAPRLP-----EAPALPFARPPAMS 115
           VQVWF NRRA+WR+Q            +  G    A P LP     E    P + P A+S
Sbjct: 263 VQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVS 322

Query: 116 LPLEPWLGPGP 126
            P      P P
Sbjct: 323 DPSSTVHRPQP 333


>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
          Length = 484

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 58/131 (44%), Positives = 72/131 (54%), Gaps = 16/131 (12%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LERAFE +HYPD+Y+REELA +  L E R
Sbjct: 203 EGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEAR 262

Query: 71  VQVWFQNRRAKWRRQ----------ERLESGSGAVAAPRLP-----EAPALPFARPPAMS 115
           VQVWF NRRA+WR+Q            +  G    A P LP     E    P + P A+S
Sbjct: 263 VQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVS 322

Query: 116 LPLEPWLGPGP 126
            P      P P
Sbjct: 323 DPSSTVHRPQP 333


>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
          Length = 479

 Score = 99.0 bits (245), Expect = 2e-21
 Identities = 58/131 (44%), Positives = 72/131 (54%), Gaps = 16/131 (12%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LERAFE +HYPD+Y+REELA +  L E R
Sbjct: 203 EGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEAR 262

Query: 71  VQVWFQNRRAKWRRQ----------ERLESGSGAVAAPRLP-----EAPALPFARPPAMS 115
           VQVWF NRRA+WR+Q            +  G    A P LP     E    P + P A+S
Sbjct: 263 VQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPTAMPTLPTYQLSETSYQPTSIPQAVS 322

Query: 116 LPLEPWLGPGP 126
            P      P P
Sbjct: 323 DPSSTVHRPQP 333


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 98.6 bits (244), Expect = 3e-21
 Identities = 46/79 (58%), Positives = 57/79 (72%)

Query: 18  PGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQN 77
           P +E+P  K RR RT FT +QL +LE+AF  SHYPDV+ RE LA ++ L E RVQVWFQN
Sbjct: 96  PDKESPGCKRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQN 155

Query: 78  RRAKWRRQERLESGSGAVA 96
           RRAKWR++E  + G G  A
Sbjct: 156 RRAKWRKKENTKKGPGRPA 174


>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 97.8 bits (242), Expect = 5e-21
 Identities = 42/67 (62%), Positives = 55/67 (82%)

Query: 24  KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
           K+K +RNRT+FT  Q+  LE+ FE +HYPDV++RE LAAK+ LPE R+QVWF NRRAKWR
Sbjct: 207 KRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWR 266

Query: 84  RQERLES 90
           R+E+L +
Sbjct: 267 REEKLRN 273


>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
          Length = 436

 Score = 97.8 bits (242), Expect = 5e-21
 Identities = 42/67 (62%), Positives = 55/67 (82%)

Query: 24  KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
           K+K +RNRT+FT  Q+  LE+ FE +HYPDV++RE LAAK+ LPE R+QVWF NRRAKWR
Sbjct: 221 KRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWR 280

Query: 84  RQERLES 90
           R+E+L +
Sbjct: 281 REEKLRN 287


>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
          Length = 422

 Score = 97.8 bits (242), Expect = 5e-21
 Identities = 42/67 (62%), Positives = 55/67 (82%)

Query: 24  KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
           K+K +RNRT+FT  Q+  LE+ FE +HYPDV++RE LAAK+ LPE R+QVWF NRRAKWR
Sbjct: 207 KRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWR 266

Query: 84  RQERLES 90
           R+E+L +
Sbjct: 267 REEKLRN 273


>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 97.4 bits (241), Expect = 6e-21
 Identities = 58/152 (38%), Positives = 83/152 (54%), Gaps = 15/152 (9%)

Query: 5   PGEGPATEGGG--LGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAA 62
           P + P  +GG      G++  ++K +R+RT FT  QL++LER+F  +HYPD++ REELA 
Sbjct: 80  PDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELAL 139

Query: 63  KVHLPEVRVQVWFQNRRAKWRRQER----LESGSGAVAAPRLPEAPALPFARPPAMSLPL 118
           ++ L E RVQVWFQNRRAKW+++++      +    +  P LP+ P+   A   AM   L
Sbjct: 140 RIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSL 199

Query: 119 -------EPWLGPGPPAVPGLPRLLGPGPGLQ 143
                    W     P V  LP  L P  G Q
Sbjct: 200 CSFHANDTRWAAAAMPGVSQLP--LPPALGRQ 229


>gi|14149760 orthopedia homeobox [Homo sapiens]
          Length = 325

 Score = 97.4 bits (241), Expect = 6e-21
 Identities = 58/152 (38%), Positives = 83/152 (54%), Gaps = 15/152 (9%)

Query: 5   PGEGPATEGGG--LGPGEEAPKKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAA 62
           P + P  +GG      G++  ++K +R+RT FT  QL++LER+F  +HYPD++ REELA 
Sbjct: 80  PDKQPGPQGGPNPSQAGQQQGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELAL 139

Query: 63  KVHLPEVRVQVWFQNRRAKWRRQER----LESGSGAVAAPRLPEAPALPFARPPAMSLPL 118
           ++ L E RVQVWFQNRRAKW+++++      +    +  P LP+ P+   A   AM   L
Sbjct: 140 RIGLTESRVQVWFQNRRAKWKKRKKTTNVFRAPGTLLPTPGLPQFPSAAAAAAAAMGDSL 199

Query: 119 -------EPWLGPGPPAVPGLPRLLGPGPGLQ 143
                    W     P V  LP  L P  G Q
Sbjct: 200 CSFHANDTRWAAAAMPGVSQLP--LPPALGRQ 229


>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
          Length = 268

 Score = 97.1 bits (240), Expect = 8e-21
 Identities = 53/105 (50%), Positives = 64/105 (60%), Gaps = 8/105 (7%)

Query: 24  KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
           ++K RRNRTTFT  QL  LE  F  +HYPDV++REELA K++L E RVQVWFQNRRAKWR
Sbjct: 35  RRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNRRAKWR 94

Query: 84  RQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGPGPPA 128
           + ER    S      + P A   P   PP  ++   P   PG  A
Sbjct: 95  KTER--GASDQEPGAKEPMAEVTP---PPVRNINSPP---PGDQA 131


>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
          Length = 520

 Score = 96.3 bits (238), Expect = 1e-20
 Identities = 54/114 (47%), Positives = 70/114 (61%), Gaps = 9/114 (7%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LE+AFE +HYPD+Y+REELA +  L E R
Sbjct: 201 EGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEAR 260

Query: 71  VQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGP 124
           VQVWF NRRA+WR+Q    +G+  +AA        LP   PP     L P+  P
Sbjct: 261 VQVWFSNRRARWRKQ----AGANQLAAFN----HLLPGGFPPTGMPTLPPYQLP 306


>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
          Length = 518

 Score = 96.3 bits (238), Expect = 1e-20
 Identities = 54/114 (47%), Positives = 70/114 (61%), Gaps = 9/114 (7%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LE+AFE +HYPD+Y+REELA +  L E R
Sbjct: 199 EGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEAR 258

Query: 71  VQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGP 124
           VQVWF NRRA+WR+Q    +G+  +AA        LP   PP     L P+  P
Sbjct: 259 VQVWFSNRRARWRKQ----AGANQLAAFN----HLLPGGFPPTGMPTLPPYQLP 304


>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
          Length = 505

 Score = 96.3 bits (238), Expect = 1e-20
 Identities = 54/114 (47%), Positives = 70/114 (61%), Gaps = 9/114 (7%)

Query: 12  EGGGLGPGEEAP-KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVR 70
           EG  +    + P K+K RR+RTTFT  QL +LE+AFE +HYPD+Y+REELA +  L E R
Sbjct: 201 EGSDVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEAR 260

Query: 71  VQVWFQNRRAKWRRQERLESGSGAVAAPRLPEAPALPFARPPAMSLPLEPWLGP 124
           VQVWF NRRA+WR+Q    +G+  +AA        LP   PP     L P+  P
Sbjct: 261 VQVWFSNRRARWRKQ----AGANQLAAFN----HLLPGGFPPTGMPTLPPYQLP 306


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,011,237
Number of Sequences: 37866
Number of extensions: 610918
Number of successful extensions: 6342
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 390
Number of HSP's successfully gapped in prelim test: 481
Number of HSP's that attempted gapping in prelim test: 4117
Number of HSP's gapped (non-prelim): 2406
length of query: 184
length of database: 18,247,518
effective HSP length: 96
effective length of query: 88
effective length of database: 14,612,382
effective search space: 1285889616
effective search space used: 1285889616
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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