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Search of human proteins with 14211941
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
(543 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14211941 gap junction protein, alpha 10 [Homo sapiens] 1128 0.0
gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens] 363 e-100
gi|55953076 connexin 50 [Homo sapiens] 285 6e-77
gi|22779877 connexin 46 [Homo sapiens] 281 8e-76
gi|32483412 connexin 40 [Homo sapiens] 267 2e-71
gi|6631083 connexin 40 [Homo sapiens] 267 2e-71
gi|62865885 connexin 37 [Homo sapiens] 257 2e-68
gi|4504001 connexin 43 [Homo sapiens] 249 6e-66
gi|122939172 connexin 45 [Homo sapiens] 238 1e-62
gi|69122473 connexin 45 [Homo sapiens] 238 1e-62
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens] 218 1e-56
gi|42558283 gap junction protein beta 2 [Homo sapiens] 213 3e-55
gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens] 204 2e-52
gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens] 204 2e-52
gi|159032020 gap junction protein, beta 6 [Homo sapiens] 196 5e-50
gi|158966714 gap junction protein, beta 6 [Homo sapiens] 196 5e-50
gi|158966717 gap junction protein, beta 6 [Homo sapiens] 196 5e-50
gi|40254837 gap junction protein, beta 6 [Homo sapiens] 196 5e-50
gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens] 196 5e-50
gi|23397464 gap junction protein, beta 4 [Homo sapiens] 188 9e-48
gi|54607056 connexin 31 [Homo sapiens] 179 4e-45
gi|13128960 connexin 31 [Homo sapiens] 179 4e-45
gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens] 179 6e-45
gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens] 177 2e-44
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 177 2e-44
gi|145699105 connexin40.1 [Homo sapiens] 155 7e-38
gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens] 143 4e-34
gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens] 90 6e-18
gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens] 90 6e-18
gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens] 90 6e-18
>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
Length = 543
Score = 1128 bits (2918), Expect = 0.0
Identities = 543/543 (100%), Positives = 543/543 (100%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG
Sbjct: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN
Sbjct: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
Query: 121 PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG 180
PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG
Sbjct: 121 PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG 180
Query: 181 FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR
Sbjct: 181 FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
Query: 241 TLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVPKSK 300
TLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVPKSK
Sbjct: 241 TLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVPKSK 300
Query: 301 TMWQIPQPRQLEVDPSNGKKDWSEKDQHSGQLHVHSPCPWAGSAGNQHLGQQSDHSSFGL 360
TMWQIPQPRQLEVDPSNGKKDWSEKDQHSGQLHVHSPCPWAGSAGNQHLGQQSDHSSFGL
Sbjct: 301 TMWQIPQPRQLEVDPSNGKKDWSEKDQHSGQLHVHSPCPWAGSAGNQHLGQQSDHSSFGL 360
Query: 361 QNTMSQSWLGTTTAPRNCPSFAVGTWEQSQDPEPSGEPLTDLHSHCRDSEGSMRESGVWI 420
QNTMSQSWLGTTTAPRNCPSFAVGTWEQSQDPEPSGEPLTDLHSHCRDSEGSMRESGVWI
Sbjct: 361 QNTMSQSWLGTTTAPRNCPSFAVGTWEQSQDPEPSGEPLTDLHSHCRDSEGSMRESGVWI 420
Query: 421 DRSRPGSRKASFLSRLLSEKRHLHSDSGSSGSRNSSCLDFPHWENSPSPLPSVTGHRTSM 480
DRSRPGSRKASFLSRLLSEKRHLHSDSGSSGSRNSSCLDFPHWENSPSPLPSVTGHRTSM
Sbjct: 421 DRSRPGSRKASFLSRLLSEKRHLHSDSGSSGSRNSSCLDFPHWENSPSPLPSVTGHRTSM 480
Query: 481 VRQAALPIMELSQELFHSGCFLFPFFLPGVCMYVCVDREADGGGDYLWRDKIIHSIHSVK 540
VRQAALPIMELSQELFHSGCFLFPFFLPGVCMYVCVDREADGGGDYLWRDKIIHSIHSVK
Sbjct: 481 VRQAALPIMELSQELFHSGCFLFPFFLPGVCMYVCVDREADGGGDYLWRDKIIHSIHSVK 540
Query: 541 FNS 543
FNS
Sbjct: 541 FNS 543
>gi|31542845 gap junction protein, alpha 9, 59kDa [Homo sapiens]
Length = 515
Score = 363 bits (933), Expect = e-100
Identities = 177/264 (67%), Positives = 214/264 (81%), Gaps = 6/264 (2%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MGDWNLLG LEEVH HST++GKIWLTILFIFRMLVL VAAEDVW+DEQS F CNT QPG
Sbjct: 1 MGDWNLLGDTLEEVHIHSTMIGKIWLTILFIFRMLVLGVAAEDVWNDEQSGFICNTEQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
C N+CYD AFPISLIR+WVLQ+IFVSSPSLVYMGHALYRLR E++RQR K+ LR ++E
Sbjct: 61 CRNVCYDQAFPISLIRYWVLQVIFVSSPSLVYMGHALYRLRVLEEERQRMKAQLRVELEE 120
Query: 121 PDLDL-EEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY 179
+ ++ +++R+++EL +LE++K ++K PL+G LL TYV+HI TRSV+EVGFMIGQY+LY
Sbjct: 121 VEFEMPRDRRRLEQELCQLEKRK-LNKAPLRGTLLCTYVIHIFTRSVVEVGFMIGQYLLY 179
Query: 180 GFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIM 239
GF + PL+KC PCPN +DCFVSRPTEKTIF+LFM SIA ISL LNILEIFHLG +KI
Sbjct: 180 GFHLEPLFKCHGHPCPNIIDCFVSRPTEKTIFLLFMQSIATISLFLNILEIFHLGFKKIK 239
Query: 240 RTLYKKSSSEGIEDETGPPFHLKK 263
R L+ K + +E FH K
Sbjct: 240 RGLWGKYKLKKEHNE----FHANK 259
>gi|55953076 connexin 50 [Homo sapiens]
Length = 433
Score = 285 bits (730), Expect = 6e-77
Identities = 135/245 (55%), Positives = 180/245 (73%), Gaps = 12/245 (4%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MGDW+ LG ILEEV+ HST++G++WLT+LFIFR+L+L AAE VW DEQS F CNT+QPG
Sbjct: 1 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQM-- 118
C N+CYD+AFPIS IR WVLQIIFVS+PSL+Y+GHA++ +R EK + R+ L Q
Sbjct: 61 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT 120
Query: 119 -ENPDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYI 177
PD +++ K K L+G LLRTY+ HI+ +++ EVGF++G Y
Sbjct: 121 NGGPD---------QGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYF 171
Query: 178 LYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRK 237
LYGF++ PLY+C++ PCPN VDCFVSRPTEKTIF+LFM S+A++SL LN++E+ HLG++
Sbjct: 172 LYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKG 231
Query: 238 IMRTL 242
I L
Sbjct: 232 IRSAL 236
>gi|22779877 connexin 46 [Homo sapiens]
Length = 435
Score = 281 bits (720), Expect = 8e-76
Identities = 135/259 (52%), Positives = 184/259 (71%), Gaps = 14/259 (5%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MGDW+ LG +LE HST++GK+WLT+LFIFR+LVL AAEDVW DEQS F CNT+QPG
Sbjct: 1 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQR-KKSHLRAQME 119
C N+CYD AFPIS IRFW LQIIFVS+P+L+Y+GH L+ +R EK ++R ++ L+ +
Sbjct: 61 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP 120
Query: 120 NPDLDLEE--QQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYI 177
+P ++ R DR +V + G LLRTYV +I+ +++ EVGF+ GQY
Sbjct: 121 SPKEPPQDNPSSRDDR-----------GRVRMAGALLRTYVFNIIFKTLFEVGFIAGQYF 169
Query: 178 LYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRK 237
LYGF++ PLY+C + PCPN VDCF+SRPTEKTIF++FM ++A SLLLN+LEI+HLG +K
Sbjct: 170 LYGFELKPLYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKK 229
Query: 238 IMRTLYKKSSSEGIEDETG 256
+ + + + + E G
Sbjct: 230 LKQGVTSRLGPDASEAPLG 248
>gi|32483412 connexin 40 [Homo sapiens]
Length = 358
Score = 267 bits (683), Expect = 2e-71
Identities = 132/244 (54%), Positives = 173/244 (70%), Gaps = 4/244 (1%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MGDW+ LG LEEVH HST+VGK+WLT+LFIFRMLVL AAE W DEQ+ F C+T QPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
C N+CYD AFPIS IR+WVLQIIFVS+PSLVYMGHA++ +R EK + R+ RA+
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE--RAKEVR 118
Query: 121 PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG 180
E EL EE ++ L+G LL TYV IL R+ +EVGF++GQY +YG
Sbjct: 119 GSGSYEYPVAEKAELSCWEEGN--GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
Query: 181 FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
+ L+ C + PCP+ V+C+VSRPTEK +F++FM ++AA+SLLL++ E++HLG +KI +
Sbjct: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
Query: 241 TLYK 244
K
Sbjct: 237 RFVK 240
>gi|6631083 connexin 40 [Homo sapiens]
Length = 358
Score = 267 bits (683), Expect = 2e-71
Identities = 132/244 (54%), Positives = 173/244 (70%), Gaps = 4/244 (1%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MGDW+ LG LEEVH HST+VGK+WLT+LFIFRMLVL AAE W DEQ+ F C+T QPG
Sbjct: 1 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
C N+CYD AFPIS IR+WVLQIIFVS+PSLVYMGHA++ +R EK + R+ RA+
Sbjct: 61 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAE--RAKEVR 118
Query: 121 PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG 180
E EL EE ++ L+G LL TYV IL R+ +EVGF++GQY +YG
Sbjct: 119 GSGSYEYPVAEKAELSCWEEGN--GRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYG 176
Query: 181 FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
+ L+ C + PCP+ V+C+VSRPTEK +F++FM ++AA+SLLL++ E++HLG +KI +
Sbjct: 177 IFLTTLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQ 236
Query: 241 TLYK 244
K
Sbjct: 237 RFVK 240
>gi|62865885 connexin 37 [Homo sapiens]
Length = 333
Score = 257 bits (656), Expect = 2e-68
Identities = 125/250 (50%), Positives = 176/250 (70%), Gaps = 4/250 (1%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MGDW L +L++V HST+VGKIWLT+LFIFR+L+L +A E VW DEQS F CNT QPG
Sbjct: 1 MGDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRA-QME 119
C N+CYD AFPIS IR+WVLQ +FVS+P+LVY+GH +Y R E+ RQ K+ LRA +
Sbjct: 61 CTNVCYDQAFPISHIRYWVLQFLFVSTPTLVYLGHVIYLSRREERLRQ-KEGELRALPAK 119
Query: 120 NPDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY 179
+P ++ ++R++ ++ + ++ ++G L+ TYV +L +SVLE GF+ GQ+ LY
Sbjct: 120 DPQVE-RALAAVERQMAKISVAED-GRLRIRGALMGTYVASVLCKSVLEAGFLYGQWRLY 177
Query: 180 GFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIM 239
G+ M P++ C + PCP VDCFVSRPTEKTIF++FM + ISL+LN+LE+ HL R +
Sbjct: 178 GWTMEPVFVCQRAPCPYLVDCFVSRPTEKTIFIIFMLVVGLISLVLNLLELVHLLCRCLS 237
Query: 240 RTLYKKSSSE 249
R + + +
Sbjct: 238 RGMRARQGQD 247
>gi|4504001 connexin 43 [Homo sapiens]
Length = 382
Score = 249 bits (635), Expect = 6e-66
Identities = 117/247 (47%), Positives = 176/247 (71%), Gaps = 4/247 (1%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MGDW+ LG +L++V ++ST GK+WL++LFIFR+L+L A E W DEQSAF CNT+QPG
Sbjct: 1 MGDWSALGKLLDKVQAYSTAGGKVWLSVLFIFRILLLGTAVESAWGDEQSAFRCNTQQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
C N+CYD +FPIS +RFWVLQIIFVS P+L+Y+ H Y +R EK ++++ AQ +
Sbjct: 61 CENVCYDKSFPISHVRFWVLQIIFVSVPTLLYLAHVFYVMRKEEKLNKKEEELKVAQTDG 120
Query: 121 PDLDLEEQQRIDRELRRLEEQKRIH-KVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY 179
++D+ +Q E+++ + H KV ++G LLRTY++ IL +S+ EV F++ Q+ +Y
Sbjct: 121 VNVDMHLKQ---IEIKKFKYGIEEHGKVKMRGGLLRTYIISILFKSIFEVAFLLIQWYIY 177
Query: 180 GFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIM 239
GF + +Y C + PCP+ VDCF+SRPTEKTIF++FM ++ +SL LNI+E+F++ + +
Sbjct: 178 GFSLSAVYTCKRDPCPHQVDCFLSRPTEKTIFIIFMLVVSLVSLALNIIELFYVFFKGVK 237
Query: 240 RTLYKKS 246
+ KS
Sbjct: 238 DRVKGKS 244
>gi|122939172 connexin 45 [Homo sapiens]
Length = 396
Score = 238 bits (607), Expect = 1e-62
Identities = 117/264 (44%), Positives = 167/264 (63%), Gaps = 23/264 (8%)
Query: 4 WNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNN 63
W+ L +LEE+H+HST VGKIWLT+L +FR+++ V E ++ DEQS F CNT QPGC N
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 ICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKS----------H 113
+CYD P+S +RFWV QII V++PS++Y+G+A++++ E KK+
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 114 LRAQMENPDLDLEEQQRI--------DRELRRLEEQKRIH----KVPLKGCLLRTYVLHI 161
+E + D EE + D+E + + K H ++ G L++ YVL +
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYVLQL 181
Query: 162 LTRSVLEVGFMIGQYILYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAI 221
L R+V EVGF+IGQY LYGFQ+HP Y C++ PCP+ +DCF+SRPTEKTIF+L M+ + +
Sbjct: 182 LARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGL 241
Query: 222 SLLLNILEIFHLGIRKIMRTLYKK 245
LLLNI E+ HLG I +L K
Sbjct: 242 CLLLNIWEMLHLGFGTIRDSLNSK 265
>gi|69122473 connexin 45 [Homo sapiens]
Length = 396
Score = 238 bits (607), Expect = 1e-62
Identities = 117/264 (44%), Positives = 167/264 (63%), Gaps = 23/264 (8%)
Query: 4 WNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNN 63
W+ L +LEE+H+HST VGKIWLT+L +FR+++ V E ++ DEQS F CNT QPGC N
Sbjct: 3 WSFLTRLLEEIHNHSTFVGKIWLTVLIVFRIVLTAVGGESIYYDEQSKFVCNTEQPGCEN 62
Query: 64 ICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKS----------H 113
+CYD P+S +RFWV QII V++PS++Y+G+A++++ E KK+
Sbjct: 63 VCYDAFAPLSHVRFWVFQIILVATPSVMYLGYAIHKIAKMEHGEADKKAARSKPYAMRWK 122
Query: 114 LRAQMENPDLDLEEQQRI--------DRELRRLEEQKRIH----KVPLKGCLLRTYVLHI 161
+E + D EE + D+E + + K H ++ G L++ YVL +
Sbjct: 123 QHRALEETEEDNEEDPMMYPEMELESDKENKEQSQPKPKHDGRRRIREDG-LMKIYVLQL 181
Query: 162 LTRSVLEVGFMIGQYILYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAI 221
L R+V EVGF+IGQY LYGFQ+HP Y C++ PCP+ +DCF+SRPTEKTIF+L M+ + +
Sbjct: 182 LARTVFEVGFLIGQYFLYGFQVHPFYVCSRLPCPHKIDCFISRPTEKTIFLLIMYGVTGL 241
Query: 222 SLLLNILEIFHLGIRKIMRTLYKK 245
LLLNI E+ HLG I +L K
Sbjct: 242 CLLLNIWEMLHLGFGTIRDSLNSK 265
>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
Length = 439
Score = 218 bits (555), Expect = 1e-56
Identities = 116/313 (37%), Positives = 178/313 (56%), Gaps = 71/313 (22%)
Query: 4 WNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNN 63
W+ L +LEE+H+HST VGK+WLT+L +FR+++ V E ++ DEQ+ F CNTRQPGC+N
Sbjct: 6 WSFLTRLLEEIHNHSTFVGKVWLTVLVVFRIVLTAVGGEAIYSDEQAKFTCNTRQPGCDN 65
Query: 64 ICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRL-RAFEKDRQR-----------KK 111
+CYD P+S +RFWV QI+ +S+PS++Y+G+A++RL RA E++R+R +
Sbjct: 66 VCYDAFAPLSHVRFWVFQIVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPRRAPR 125
Query: 112 SHLRAQ-----------MENPDLDLEEQQRIDR-----------ELRRLEE--------- 140
+HL E P L L E++ + E EE
Sbjct: 126 AHLPPPHAGWPEPADLGEEEPMLGLGEEEEEEETGAAEGAGEEAEEAGAEEACTKAVGAD 185
Query: 141 ---------------QKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYGFQMHP 185
++RI + L +R YV ++ R+ EV F++GQY+LYGF++ P
Sbjct: 186 GKAAGTPGPTGQHDGRRRIQREGL----MRVYVAQLVARAAFEVAFLVGQYLLYGFEVRP 241
Query: 186 LYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYKK 245
+ C++ PCP+ VDCFVSRPTEKT+F+L M+ ++ + LLLN+ E+ HLG+
Sbjct: 242 FFPCSRQPCPHVVDCFVSRPTEKTVFLLVMYVVSCLCLLLNLCEMAHLGL---------G 292
Query: 246 SSSEGIEDETGPP 258
S+ + + GPP
Sbjct: 293 SAQDAVRGRRGPP 305
>gi|42558283 gap junction protein beta 2 [Homo sapiens]
Length = 226
Score = 213 bits (543), Expect = 3e-55
Identities = 109/235 (46%), Positives = 148/235 (62%), Gaps = 21/235 (8%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
DW L IL V+ HST +GKIWLT+LFIFR+++L VAA++VW DEQ+ F CNT QPGC
Sbjct: 2 DWGTLQTILGGVNKHSTSIGKIWLTVLFIFRIMILVVAAKEVWGDEQADFVCNTLQPGCK 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+CYD FPIS IR W LQ+IFVS+P+L+ H YR ++K+ ++ ++++
Sbjct: 62 NVCYDHYFPISHIRLWALQLIFVSTPALLVAMHVAYR------RHEKKRKFIKGEIKSEF 115
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
D+EE + KV ++G L TY I R + E FM Y++Y GF
Sbjct: 116 KDIEE--------------IKTQKVRIEGSLWWTYTSSIFFRVIFEAAFMYVFYVMYDGF 161
Query: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIR 236
M L KC PCPN VDCFVSRPTEKT+F +FM +++ I +LLN+ E+ +L IR
Sbjct: 162 SMQRLVKCNAWPCPNTVDCFVSRPTEKTVFTVFMIAVSGICILLNVTELCYLLIR 216
>gi|148233402 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 204 bits (519), Expect = 2e-52
Identities = 107/246 (43%), Positives = 152/246 (61%), Gaps = 22/246 (8%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
+W L +L V+ HST +G++WL+++FIFR++VL VAAE VW DE+S+F CNT QPGCN
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
++CYD FPIS +R W LQ+I VS+P+L+ H ++ + +K LR +
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQ-------QHIEKKMLRLEGHGDP 114
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
L LEE +R HKV + G L TYV+ ++ R + E FM Y+LY G+
Sbjct: 115 LHLEEVKR--------------HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGY 160
Query: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRT 241
M L KC PCPN VDCFVSRPTEKT+F +FM + + I ++LN+ E+ +L IR R
Sbjct: 161 AMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARR 220
Query: 242 LYKKSS 247
++S+
Sbjct: 221 AQRRSN 226
>gi|4504005 gap junction protein, beta 1, 32kDa [Homo sapiens]
Length = 283
Score = 204 bits (519), Expect = 2e-52
Identities = 107/246 (43%), Positives = 152/246 (61%), Gaps = 22/246 (8%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
+W L +L V+ HST +G++WL+++FIFR++VL VAAE VW DE+S+F CNT QPGCN
Sbjct: 2 NWTGLYTLLSGVNRHSTAIGRVWLSVIFIFRIMVLVVAAESVWGDEKSSFICNTLQPGCN 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
++CYD FPIS +R W LQ+I VS+P+L+ H ++ + +K LR +
Sbjct: 62 SVCYDQFFPISHVRLWSLQLILVSTPALLVAMHVAHQ-------QHIEKKMLRLEGHGDP 114
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
L LEE +R HKV + G L TYV+ ++ R + E FM Y+LY G+
Sbjct: 115 LHLEEVKR--------------HKVHISGTLWWTYVISVVFRLLFEAVFMYVFYLLYPGY 160
Query: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRT 241
M L KC PCPN VDCFVSRPTEKT+F +FM + + I ++LN+ E+ +L IR R
Sbjct: 161 AMVRLVKCDVYPCPNTVDCFVSRPTEKTVFTVFMLAASGICIILNVAEVVYLIIRACARR 220
Query: 242 LYKKSS 247
++S+
Sbjct: 221 AQRRSN 226
>gi|159032020 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 196 bits (498), Expect = 5e-50
Identities = 101/239 (42%), Positives = 142/239 (59%), Gaps = 21/239 (8%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
DW L + V+ HST +GK+W+T++FIFR+++L VAA++VW DEQ F CNT QPGC
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+CYD FP+S IR W LQ+IFVS+P+L+ H Y + + RK R + N
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY----YRHETTRK--FRRGEKRNDF 115
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
D+E+ ++ KV ++G L TY I R + E FM Y LY G+
Sbjct: 116 KDIEDIKK--------------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
Query: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
+ + KC PCPN VDCF+SRPTEKT+F +FM S + I +LLN+ E+ +L ++ R
Sbjct: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR 220
>gi|158966714 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 196 bits (498), Expect = 5e-50
Identities = 101/239 (42%), Positives = 142/239 (59%), Gaps = 21/239 (8%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
DW L + V+ HST +GK+W+T++FIFR+++L VAA++VW DEQ F CNT QPGC
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+CYD FP+S IR W LQ+IFVS+P+L+ H Y + + RK R + N
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY----YRHETTRK--FRRGEKRNDF 115
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
D+E+ ++ KV ++G L TY I R + E FM Y LY G+
Sbjct: 116 KDIEDIKK--------------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
Query: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
+ + KC PCPN VDCF+SRPTEKT+F +FM S + I +LLN+ E+ +L ++ R
Sbjct: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR 220
>gi|158966717 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 196 bits (498), Expect = 5e-50
Identities = 101/239 (42%), Positives = 142/239 (59%), Gaps = 21/239 (8%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
DW L + V+ HST +GK+W+T++FIFR+++L VAA++VW DEQ F CNT QPGC
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+CYD FP+S IR W LQ+IFVS+P+L+ H Y + + RK R + N
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY----YRHETTRK--FRRGEKRNDF 115
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
D+E+ ++ KV ++G L TY I R + E FM Y LY G+
Sbjct: 116 KDIEDIKK--------------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
Query: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
+ + KC PCPN VDCF+SRPTEKT+F +FM S + I +LLN+ E+ +L ++ R
Sbjct: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR 220
>gi|40254837 gap junction protein, beta 6 [Homo sapiens]
Length = 261
Score = 196 bits (498), Expect = 5e-50
Identities = 101/239 (42%), Positives = 142/239 (59%), Gaps = 21/239 (8%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
DW L + V+ HST +GK+W+T++FIFR+++L VAA++VW DEQ F CNT QPGC
Sbjct: 2 DWGTLHTFIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCK 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+CYD FP+S IR W LQ+IFVS+P+L+ H Y + + RK R + N
Sbjct: 62 NVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAY----YRHETTRK--FRRGEKRNDF 115
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
D+E+ ++ KV ++G L TY I R + E FM Y LY G+
Sbjct: 116 KDIEDIKK--------------QKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGY 161
Query: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
+ + KC PCPN VDCF+SRPTEKT+F +FM S + I +LLN+ E+ +L ++ R
Sbjct: 162 HLPWVLKCGIDPCPNLVDCFISRPTEKTVFTIFMISASVICMLLNVAELCYLLLKVCFR 220
>gi|10190698 gap junction protein, delta 2, 36kDa [Homo sapiens]
Length = 321
Score = 196 bits (498), Expect = 5e-50
Identities = 107/281 (38%), Positives = 165/281 (58%), Gaps = 44/281 (15%)
Query: 1 MGDWNLLGGILEE-VHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQP 59
MG+W +L +LE V HST++G+I LT++ IFR+L++ + E V+DDEQ+ F CNT QP
Sbjct: 1 MGEWTILERLLEAAVQQHSTMIGRILLTVVVIFRILIVAIVGETVYDDEQTMFVCNTLQP 60
Query: 60 GCNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQME 119
GCN CYD AFPIS IR+WV QII V +PSL ++ +++++ A +++R+ L +
Sbjct: 61 GCNQACYDRAFPISHIRYWVFQIIMVCTPSLCFITYSVHQ-SAKQRERRYSTVFLALDRD 119
Query: 120 NPDL----------DLEEQQRIDRELRR------LEEQKRIHKVPLKGCL---------- 153
P+ +R D++L+ L+ + K CL
Sbjct: 120 PPESIGGPGGTGGGGSGGGKREDKKLQNAIVNGVLQNTENTSKETEPDCLEVKELTPHPS 179
Query: 154 -LRT---------------YVLHILTRSVLEVGFMIGQYILYGFQMHPLYKCTQPPCPNA 197
LRT Y++ ++ R+ LE+GF++GQY LYGF + LY+C + PC
Sbjct: 180 GLRTASKSKLRRQEGISRFYIIQVVFRNALEIGFLVGQYFLYGFSVPGLYECNRYPCIKE 239
Query: 198 VDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKI 238
V+C+VSRPTEKT+F++FM +++ I ++LN+ E+ HLG RKI
Sbjct: 240 VECYVSRPTEKTVFLVFMFAVSGICVVLNLAELNHLGWRKI 280
>gi|23397464 gap junction protein, beta 4 [Homo sapiens]
Length = 266
Score = 188 bits (478), Expect = 9e-48
Identities = 98/265 (36%), Positives = 155/265 (58%), Gaps = 29/265 (10%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
+W L G+L V+ +ST++ +IWL+++FIFR+LV VAAE+VWDDEQ F CNT+QPGC
Sbjct: 2 NWAFLQGLLSGVNKYSTVLSRIWLSVVFIFRVLVYVVAAEEVWDDEQKDFVCNTKQPGCP 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+CYD+ FP+S +R W LQ+I V+ PSL+ + H YR + + +K HL+ P
Sbjct: 62 NVCYDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR------EERERKHHLKHGPNAPS 115
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
L ++ +G L TY+L ++ ++ ++ GF+ + LY +
Sbjct: 116 LYDNLSKK-------------------RGGLWWTYLLSLIFKAAVDAGFLYIFHRLYKDY 156
Query: 182 QMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRT 241
M + C+ PCP+ VDC++SRPTEK +F FM + AAI +LLN+ E+F+L ++ M
Sbjct: 157 DMPRVVACSVEPCPHTVDCYISRPTEKKVFTYFMVTTAAICILLNLSEVFYLVGKRCMEI 216
Query: 242 L---YKKSSSEGIEDETGPPFHLKK 263
+++ +T PP+ L +
Sbjct: 217 FGPRHRRPRCRECLPDTCPPYVLSQ 241
>gi|54607056 connexin 31 [Homo sapiens]
Length = 270
Score = 179 bits (455), Expect = 4e-45
Identities = 107/298 (35%), Positives = 159/298 (53%), Gaps = 36/298 (12%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
DW L +L V+ +ST G+IWL+++F+FR+LV VAAE VW DEQ F CNT+QPGC
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+CYD+ FPIS IR W LQ+IFV+ PSL+ + H YR E++R+ ++ H
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYRE---ERERRHRQKHG-------- 110
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
D+ + + + H G L TY+ ++ + ++E F+ + L+ GF
Sbjct: 111 ---------DQCAKLYDNAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGF 156
Query: 182 QMHPLYKCTQ-PPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
M L +C PCPN VDC+++RPTEK IF FM +A+ ++L I E+ +L +++R
Sbjct: 157 NMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
Query: 241 TLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPE--RISPLQANNQQQVIRVNV 296
L+K G + S A C L E + P NN+ Q N+
Sbjct: 217 GLHKDKPRGGCSPSSSA-------SRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNL 267
>gi|13128960 connexin 31 [Homo sapiens]
Length = 270
Score = 179 bits (455), Expect = 4e-45
Identities = 107/298 (35%), Positives = 159/298 (53%), Gaps = 36/298 (12%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
DW L +L V+ +ST G+IWL+++F+FR+LV VAAE VW DEQ F CNT+QPGC
Sbjct: 2 DWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCT 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+CYD+ FPIS IR W LQ+IFV+ PSL+ + H YR E++R+ ++ H
Sbjct: 62 NVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYRE---ERERRHRQKHG-------- 110
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GF 181
D+ + + + H G L TY+ ++ + ++E F+ + L+ GF
Sbjct: 111 ---------DQCAKLYDNAGKKH-----GGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGF 156
Query: 182 QMHPLYKCTQ-PPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMR 240
M L +C PCPN VDC+++RPTEK IF FM +A+ ++L I E+ +L +++R
Sbjct: 157 NMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLR 216
Query: 241 TLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPE--RISPLQANNQQQVIRVNV 296
L+K G + S A C L E + P NN+ Q N+
Sbjct: 217 GLHKDKPRGGCSPSSSA-------SRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNL 267
>gi|38348412 gap junction protein, beta 7, 25kDa [Homo sapiens]
Length = 223
Score = 179 bits (454), Expect = 6e-45
Identities = 93/243 (38%), Positives = 137/243 (56%), Gaps = 33/243 (13%)
Query: 4 WNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNN 63
W L +L V+ +ST G IWL ++F+FR+LV VAAE VW DEQ F CN+RQPGC N
Sbjct: 3 WMFLRDLLSGVNKYSTGTGWIWLAVVFVFRLLVYMVAAEHVWKDEQKEFECNSRQPGCKN 62
Query: 64 ICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPDL 123
+C+DD FPIS +R W LQ+I VS+PSL+ + H Y R+K H + +P
Sbjct: 63 VCFDDFFPISQVRLWALQLIMVSTPSLLVVLHVAYH-------EGREKRHRKKLYVSPG- 114
Query: 124 DLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILY-GFQ 182
+ G L Y++ ++ ++ E+GF++ Y LY GF
Sbjct: 115 ------------------------TMDGGLWYAYLISLIVKTGFEIGFLVLFYKLYDGFS 150
Query: 183 MHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTL 242
+ L KC PCPN VDCF+S+PTEKTIF+LF+ + + ++LN +E+ L ++ ++
Sbjct: 151 VPYLIKCDLKPCPNTVDCFISKPTEKTIFILFLVITSCLCIVLNFIELSFLVLKCFIKCC 210
Query: 243 YKK 245
+K
Sbjct: 211 LQK 213
>gi|148839378 gap junction protein, delta 3, 31.9kDa [Homo sapiens]
Length = 294
Score = 177 bits (449), Expect = 2e-44
Identities = 90/233 (38%), Positives = 136/233 (58%), Gaps = 21/233 (9%)
Query: 1 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG 60
MG+W LG +L+ V S +VG++WL ++ IFR+LVL V++DEQ F CNT QPG
Sbjct: 1 MGEWAFLGSLLDAVQLQSPLVGRLWLVVMLIFRILVLATVGGAVFEDEQEEFVCNTLQPG 60
Query: 61 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN 120
C CYD AFP+S RFW+ I+ +S+P ++++ ++++R ++ + AQ
Sbjct: 61 CRQTCYDRAFPVSHYRFWLFHILLLSAPPVLFVVYSMHR-----AGKEAGGAEAAAQCAP 115
Query: 121 PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYG 180
L E Q LR + R Y+L + R + E+ F+ GQ +LYG
Sbjct: 116 ---GLPEAQCAPCALRARRAR-------------RCYLLSVALRLLAELTFLGGQALLYG 159
Query: 181 FQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHL 233
F++ P + C PPCP+ VDCFVSRPTEKT+F+LF ++ +S LL++ E+ HL
Sbjct: 160 FRVAPHFACAGPPCPHTVDCFVSRPTEKTVFVLFYFAVGLLSALLSVAELGHL 212
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 177 bits (449), Expect = 2e-44
Identities = 93/237 (39%), Positives = 140/237 (59%), Gaps = 36/237 (15%)
Query: 3 DWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCN 62
+W++ G+L V+ +ST G+IWL+++FIFR+LV V AE VW D+ F CNTRQPGC+
Sbjct: 2 NWSIFEGLLSGVNKYSTAFGRIWLSLVFIFRVLVYLVTAERVWSDDHKDFDCNTRQPGCS 61
Query: 63 NICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPD 122
N+C+D+ FP+S +R W LQ+I V+ PSL+ + H YR ++K H A EN
Sbjct: 62 NVCFDEFFPVSHVRLWALQLILVTCPSLLVVMHVAYR-------EVQEKRHREAHGEN-- 112
Query: 123 LDLEEQQRIDRELRRLEEQKRIHKVPLK--GCLLRTYVLHILTRSVLEVGFMIGQYILYG 180
R++ P K G L TYV ++ ++ +++ F+ Y+ +
Sbjct: 113 ------------------SGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFL---YVFHS 151
Query: 181 FQ----MHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHL 233
F + P+ KC PCPN VDCF+S+P+EK IF LFM + AAI +LLN++E+ +L
Sbjct: 152 FYPKYILPPVVKCHADPCPNIVDCFISKPSEKNIFTLFMVATAAICILLNLVELIYL 208
>gi|145699105 connexin40.1 [Homo sapiens]
Length = 370
Score = 155 bits (393), Expect = 7e-38
Identities = 89/256 (34%), Positives = 139/256 (54%), Gaps = 15/256 (5%)
Query: 5 NLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNI 64
+LLG ++ ++ + T+VGK+W + + RMLV+ +A V+ DEQ F CNT QPGC N+
Sbjct: 5 DLLGFLIITLNCNVTMVGKLWFVLTMLLRMLVIVLAGRPVYQDEQERFVCNTLQPGCANV 64
Query: 65 CYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPDLD 124
CYD P+S +RFW++Q + V PS V+ + L+R + L A D
Sbjct: 65 CYDVFSPVSHLRFWLIQGVCVLLPSAVFSVYVLHR-----------GATLAALGPRRCPD 113
Query: 125 LEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYILYGFQMH 184
E R R ++ +VP Y++H+L R++LE F Y L+GF
Sbjct: 114 PREPASGQRRCPRPFGERGGLQVP---DFSAGYIIHLLLRTLLEAAFGALHYFLFGFLAP 170
Query: 185 PLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYK 244
+ CT+PPC VDC+VSRPTEK++ MLF+ +++A+S LL + ++ +R+ MR
Sbjct: 171 KKFPCTRPPCTGVVDCYVSRPTEKSLLMLFLWAVSALSFLLGLADLV-CSLRRRMRRRPG 229
Query: 245 KSSSEGIEDETGPPFH 260
+S I ++G H
Sbjct: 230 PPTSPSIRKQSGASGH 245
>gi|31559821 gap junction protein, gamma 3, 30.2kDa [Homo sapiens]
Length = 279
Score = 143 bits (361), Expect = 4e-34
Identities = 90/241 (37%), Positives = 126/241 (52%), Gaps = 23/241 (9%)
Query: 10 ILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNICYDDA 69
+L E ST VG++ L +L FR+++L + V+ DEQS F C+T+QPGC C+D
Sbjct: 9 LLAEESRRSTPVGRLLLPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 68
Query: 70 FPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMENPDLDLEEQQ 129
P+S +RFWV Q+I V+ PS +YMG LY H+ E EE+
Sbjct: 69 HPLSPLRFWVFQVILVAVPSALYMGFTLY--------------HVIWHWELSGKGKEEET 114
Query: 130 RIDRELRRLEEQKRIHKVPLKGC--LLRTYVLHILTRSVLEVGFMIGQYILYGFQMHPLY 187
I + ++ VP G LL YV + R VLE + QY LYGFQM +
Sbjct: 115 LI-------QGREGNTDVPGAGSLRLLWAYVAQLGARLVLEGAALGLQYHLYGFQMPSSF 167
Query: 188 KCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRKIMRTLYKKSS 247
C + PC ++ C +SRP+EKTIF+ M ++ LL LE+ LG+ + RT KSS
Sbjct: 168 ACRREPCLGSITCNLSRPSEKTIFLKTMFGVSGFCLLFTFLELVLLGLGRWWRTWKHKSS 227
Query: 248 S 248
S
Sbjct: 228 S 228
>gi|169171704 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 89.7 bits (221), Expect = 6e-18
Identities = 40/95 (42%), Positives = 61/95 (64%)
Query: 10 ILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNICYDDA 69
+L E HST VG++ +L FR+++L + V+ DEQS F C+T+QPGC C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFE 104
P+S +RFWV Q+I V+ PS++YMG+ + F+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQ 122
>gi|169171845 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 89.7 bits (221), Expect = 6e-18
Identities = 40/95 (42%), Positives = 61/95 (64%)
Query: 10 ILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNICYDDA 69
+L E HST VG++ +L FR+++L + V+ DEQS F C+T+QPGC C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFE 104
P+S +RFWV Q+I V+ PS++YMG+ + F+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQ 122
>gi|169171183 PREDICTED: similar to hCG1770601 [Homo sapiens]
Length = 222
Score = 89.7 bits (221), Expect = 6e-18
Identities = 40/95 (42%), Positives = 61/95 (64%)
Query: 10 ILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPGCNNICYDDA 69
+L E HST VG++ +L FR+++L + V+ DEQS F C+T+QPGC C+D
Sbjct: 28 LLAEESWHSTPVGRLLFPVLLGFRLVLLAASGPGVYGDEQSEFVCHTQQPGCKAACFDAF 87
Query: 70 FPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFE 104
P+S +RFWV Q+I V+ PS++YMG+ + F+
Sbjct: 88 HPLSPLRFWVFQVILVAVPSVLYMGYTPWESGVFQ 122
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,626,645
Number of Sequences: 37866
Number of extensions: 1152613
Number of successful extensions: 4147
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 31
Number of HSP's that attempted gapping in prelim test: 3944
Number of HSP's gapped (non-prelim): 202
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.