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Search of human proteins with 9966793
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966793 leucine zipper transcription factor-like 1 [Homo
sapiens]
(299 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966793 leucine zipper transcription factor-like 1 [Homo sapi... 575 e-164
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 56 3e-08
gi|226495417 coiled-coil domain containing 102A [Homo sapiens] 55 1e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 54 2e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 54 2e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 54 2e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 54 2e-07
gi|147905592 coiled-coil domain containing 102B [Homo sapiens] 54 2e-07
gi|148233522 coiled-coil domain containing 102B [Homo sapiens] 54 2e-07
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 53 4e-07
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 52 8e-07
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 52 8e-07
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 52 8e-07
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 52 8e-07
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 52 8e-07
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 52 8e-07
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 52 8e-07
gi|4506467 radixin [Homo sapiens] 51 1e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 51 1e-06
gi|71061468 centromere protein E [Homo sapiens] 50 2e-06
gi|42794779 myosin 18A isoform b [Homo sapiens] 50 2e-06
gi|28416946 myosin 18A isoform a [Homo sapiens] 50 2e-06
gi|31542661 transmembrane protein 57 [Homo sapiens] 50 2e-06
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi... 50 2e-06
gi|31982906 cingulin-like 1 [Homo sapiens] 50 3e-06
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 49 5e-06
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 49 7e-06
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 49 7e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 48 9e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 48 9e-06
>gi|9966793 leucine zipper transcription factor-like 1 [Homo
sapiens]
Length = 299
Score = 575 bits (1482), Expect = e-164
Identities = 299/299 (100%), Positives = 299/299 (100%)
Query: 1 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG 60
MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG
Sbjct: 1 MAELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNG 60
Query: 61 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 120
LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA
Sbjct: 61 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 120
Query: 121 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 180
EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD
Sbjct: 121 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 180
Query: 181 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 240
EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL
Sbjct: 181 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 240
Query: 241 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 299
ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED
Sbjct: 241 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 299
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 56.2 bits (134), Expect = 3e-08
Identities = 79/301 (26%), Positives = 136/301 (45%), Gaps = 41/301 (13%)
Query: 22 RSKRGLRLKTVDSCFQDLK--ESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYT 79
R +R L + + DLK E+++ DEV + L LQA + + + EL +
Sbjct: 1609 RKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM-KDYQRELEEARAS 1667
Query: 80 NVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA-------------EITSS- 125
++FAQ+++ KL++ E E +L E++A E+A EIT+S
Sbjct: 1668 R----DEIFAQSKESEKKLKS--LEAEILQLQEELASSERARRHAEQERDELADEITNSA 1721
Query: 126 -NKKPILDVTK---PKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDE 181
K +LD + ++A L E E N E+L + L+ E+ A + +
Sbjct: 1722 SGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQ 1781
Query: 182 KSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLA 241
KS + A Q QL++ N++ K Q+L A+KS+F+ T++ LEE L
Sbjct: 1782 KS--DNARQ--QLERQNKELKAKLQELEG------AVKSKFKATISALEAKIGQLEEQLE 1831
Query: 242 TAKHDLLRVQEQLHMAEKELEKKFQQTAAYR----NMKEILTKKNDQIKDLRKRLAQYEP 297
+ + + EK+L++ F Q R KE + K N ++K L+++L + E
Sbjct: 1832 QEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEE 1891
Query: 298 E 298
E
Sbjct: 1892 E 1892
Score = 47.0 bits (110), Expect = 2e-05
Identities = 68/308 (22%), Positives = 138/308 (44%), Gaps = 22/308 (7%)
Query: 6 LNEHHQNEVINYMRFARSKRGL--RLKTVDSCFQDLKESRLVED---TFTIDEVSEVLNG 60
L E ++E + + + KR L L+ + + +D ++ + T EV+E+
Sbjct: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKA 1182
Query: 61 LQAVVHSEVESELINTAYTNVLLLRQLFAQAE-----KWYLKLQTDISELENRELLEQVA 115
L+ + E+++ + + L +L Q E K L+ E +N+EL +V
Sbjct: 1183 LEEETKNH-EAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVK 1241
Query: 116 EFEKAEITSSNKKPILDVTKPKL-APLNEGGTAEL-LNKEILRLQEENEKLKSRLKTIEI 173
++ + S +K+ LD +L A ++EG + L ++ +LQ E + + + L+ E
Sbjct: 1242 VLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1301
Query: 174 QATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQ 233
+ + + LE LQD Q + Q++ + +LS+ + K+ Q+ ++ E +
Sbjct: 1302 KGIKFAKDAASLESQLQDTQ--ELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEAR 1359
Query: 234 KSLEENLATAKHDLL----RVQEQLHMAE--KELEKKFQQTA-AYRNMKEILTKKNDQIK 286
K+LE+ + + L +V + L E +E +KK + A A E D+++
Sbjct: 1360 KNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLE 1419
Query: 287 DLRKRLAQ 294
+ RL Q
Sbjct: 1420 KTKNRLQQ 1427
Score = 45.8 bits (107), Expect = 5e-05
Identities = 54/270 (20%), Positives = 120/270 (44%), Gaps = 31/270 (11%)
Query: 53 EVSEVLNGLQAVVHSEVESELI-----NTAYTNVLLLRQLFAQAEKWYLKLQTD--ISEL 105
E+ E+L+ L++ V E E I ++ L + + E KLQ + +E
Sbjct: 919 ELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEA 978
Query: 106 ENRELLEQVAEFEKAEITSSNKKPILD----VTKPKLAPLNEGGT--AELLNKEILRLQE 159
+ +++ E++ E +K +++ +LA E A++ NK+ + + +
Sbjct: 979 KIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISD 1038
Query: 160 ENEKLKSRLKT----------IEIQATNALDEKSKLEKALQDLQLDQGNQKDFI-----K 204
E+LK KT ++ + T+ D+ ++L+ + +L+L +++ + +
Sbjct: 1039 LEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALAR 1098
Query: 205 AQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKK 264
D + +N + E Q + + E+ +S + + A+ + E+L + ELE
Sbjct: 1099 GDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDT 1158
Query: 265 FQQTAAYRNMKEILTKKNDQIKDLRKRLAQ 294
TAA +E+ TK+ ++ +L+K L +
Sbjct: 1159 LDTTAA---QQELRTKREQEVAELKKALEE 1185
Score = 40.4 bits (93), Expect = 0.002
Identities = 49/239 (20%), Positives = 110/239 (46%), Gaps = 30/239 (12%)
Query: 34 SCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQ--- 90
+C + ++ L + + I + S++ + H E E +L T++++ Q +
Sbjct: 746 ACERMIRALELDPNLYRIGQ-SKIFFRAGVLAHLEEERDL---KITDIIIFFQAVCRGYL 801
Query: 91 AEKWYLKLQTDISELENRELLEQVAEFEKAEITS-----SNKKPILDVTKPKLAPLNEGG 145
A K + K Q +S L + L A + K + KP+L VT+ +
Sbjct: 802 ARKAFAKKQQQLSAL--KVLQRNCAAYLKLRHWQWWRVFTKVKPLLQVTRQE-------E 852
Query: 146 TAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKA 205
+ ++E+L+++E+ K++ L+ +E + L+EK+ L + L Q + F +A
Sbjct: 853 ELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQL------QAETELFAEA 906
Query: 206 QDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKK 264
++ + +AA K E ++ L+D + EE +++ ++Q + E++L+++
Sbjct: 907 EE---MRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEE 962
Score = 36.6 bits (83), Expect = 0.028
Identities = 53/239 (22%), Positives = 93/239 (38%), Gaps = 25/239 (10%)
Query: 39 LKESRLVEDTFTIDEVSEVLNGL------QAVVHSEVESELINTAYTNVLLLRQLFAQAE 92
L E R+ E + + E E L Q V+ S++E L T + E
Sbjct: 1003 LMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTR--------QELE 1054
Query: 93 KWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPK-----LAPLNEGGTA 147
K KL + ++L++ ++ E A+ ++ ++ + K+ L + L N
Sbjct: 1055 KAKRKLDGETTDLQD-QIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV 1113
Query: 148 ELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQD 207
L +I LQE+ E K+ E Q + +E L+ L+D Q++
Sbjct: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQEL----- 1168
Query: 208 LSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQ 266
+ E VA LK ++ + + + + ATA +L EQ + LEK Q
Sbjct: 1169 RTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQ 1227
Score = 30.4 bits (67), Expect = 2.0
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 8/101 (7%)
Query: 97 KLQTDISELENR-ELLEQVAEFEKAEITSSNKKPILDVTKPKLAPL-----NEGGTAELL 150
K + IS LE + LE+ E E E ++NK ++ T+ KL + +E A+
Sbjct: 1811 KFKATISALEAKIGQLEEQLEQEAKERAAANK--LVRRTEKKLKEIFMQVEDERRHADQY 1868
Query: 151 NKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQD 191
+++ + ++LK +L+ E +AT A + KL++ L D
Sbjct: 1869 KEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDD 1909
>gi|226495417 coiled-coil domain containing 102A [Homo sapiens]
Length = 550
Score = 54.7 bits (130), Expect = 1e-07
Identities = 42/153 (27%), Positives = 79/153 (51%), Gaps = 10/153 (6%)
Query: 143 EGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDF 202
E G E L E L L+ EN+KL++++ +E AL + + + D L F
Sbjct: 357 EWGRRERLETEKLGLERENKKLRAQVGDLE----EALARRRRQTASALDCDLRASQAALF 412
Query: 203 IKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQE---QLHMAEK 259
K ++L++L++ LK +FQ+ + + + +E++ A K LRV+E +L AE
Sbjct: 413 EKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELAQAED 472
Query: 260 ELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRL 292
EL++ Q R ++ L ++ +Q ++L+ +L
Sbjct: 473 ELDEAHNQA---RKLQRSLDEQTEQSENLQVQL 502
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 53.5 bits (127), Expect = 2e-07
Identities = 69/302 (22%), Positives = 128/302 (42%), Gaps = 43/302 (14%)
Query: 22 RSKRGLRLKTVDSCFQDLKESRLVEDTFTI--DEVSEVLNGLQAVVHS---EVES----- 71
R +R L DLK+ L D+ +E + L LQA + E+E
Sbjct: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
Query: 72 -ELINTAYTNVLLLRQLFAQAEKWYLKLQTDIS---------ELENRELLEQVAEFEKAE 121
E+ TA N + L A ++LQ D++ +LE EL E++A
Sbjct: 1669 DEIFATAKENEKKAKSLEADL----MQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1724
Query: 122 ITSSNKKPILDVTKPKLAPL--NEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNAL 179
++K L+ +L E G E ++ + + ++ E+L + L T A
Sbjct: 1725 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE 1784
Query: 180 DEKSKLEKALQDLQLDQGNQKDFIKAQ---DLSNLENTVAALKSEFQKTLNDKTENQKSL 236
+ +LE+ ++L+ + +K++ ++ LE +A L+ + ++ +K KSL
Sbjct: 1785 SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1844
Query: 237 EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
++ K LL+V+++ MAE+ KE K N ++K L+++L + E
Sbjct: 1845 KQKDKKLKEILLQVEDERKMAEQ--------------YKEQAEKGNARVKQLKRQLEEAE 1890
Query: 297 PE 298
E
Sbjct: 1891 EE 1892
Score = 40.4 bits (93), Expect = 0.002
Identities = 66/276 (23%), Positives = 125/276 (45%), Gaps = 24/276 (8%)
Query: 23 SKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVL 82
+++ L+L+ V + + K +L ++ +D+ + L+ + ++ E I+ TN+
Sbjct: 965 ARQKLQLEKVTA---EAKIKKLEDEILVMDDQNNKLSKERKLLE-----ERISDLTTNLA 1016
Query: 83 LLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLN 142
+ K K ++ ISELE R E+ + E ++ + D + ++A L
Sbjct: 1017 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE-QIADL- 1074
Query: 143 EGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDF 202
+ AEL ++ + +EE + +RL Q NAL + +LE + DLQ D +++
Sbjct: 1075 QAQIAEL-KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
Query: 203 IKAQDLS--NLENTVAALKSEFQKTLNDKTENQKSL---EENLATAKHDLLRVQEQLHMA 257
+ +L + ALK+E + TL D T Q+ L E T L + + H A
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTL-DSTATQQELRAKREQEVTVLKKALDEETRSHEA 1192
Query: 258 E-KELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRL 292
+ +E+ +K Q E LT++ +Q K + L
Sbjct: 1193 QVQEMRQKHAQAV------EELTEQLEQFKRAKANL 1222
Score = 40.4 bits (93), Expect = 0.002
Identities = 58/215 (26%), Positives = 95/215 (44%), Gaps = 28/215 (13%)
Query: 104 ELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGG--TAELLNKEILR-LQEE 160
E + E+ Q+ E E + + K L+V L E + N+E R LQ +
Sbjct: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
Query: 161 NEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKS 220
+ ++ L+ Q A K KLE L+DL+L Q + + + + L A +K
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLEL-QADSAIKGREEAIKQLRKLQAQMK- 1655
Query: 221 EFQKTLNDKTENQKSLEENLATAKH----------DLLRVQEQLHMAEK-------ELEK 263
+FQ+ L D + S +E ATAK DL+++QE L AE+ E E+
Sbjct: 1656 DFQRELEDA---RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1712
Query: 264 KFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPE 298
++ A+ + + L D+ + L R+AQ E E
Sbjct: 1713 LAEELASSLSGRNAL---QDEKRRLEARIAQLEEE 1744
Score = 35.4 bits (80), Expect = 0.061
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 36/172 (20%)
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQL-----DQGNQKDFIK 204
L+K L++EN L L+ + +K KLE +Q+LQ ++ + K
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281
Query: 205 AQDLSN------------------LENTVAALKSEFQKT---LNDKTENQKSLEENLATA 243
L N L VA+L S+ Q T L ++T + ++ L
Sbjct: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341
Query: 244 KHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQY 295
+ + +Q+QL ++E+E K +N++ ++ N Q+ D +K+L +
Sbjct: 1342 EEERNSLQDQL---DEEMEAK-------QNLERHISTLNIQLSDSKKKLQDF 1383
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 53.5 bits (127), Expect = 2e-07
Identities = 69/302 (22%), Positives = 128/302 (42%), Gaps = 43/302 (14%)
Query: 22 RSKRGLRLKTVDSCFQDLKESRLVEDTFTI--DEVSEVLNGLQAVVHS---EVES----- 71
R +R L DLK+ L D+ +E + L LQA + E+E
Sbjct: 1616 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675
Query: 72 -ELINTAYTNVLLLRQLFAQAEKWYLKLQTDIS---------ELENRELLEQVAEFEKAE 121
E+ TA N + L A ++LQ D++ +LE EL E++A
Sbjct: 1676 DEIFATAKENEKKAKSLEADL----MQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1731
Query: 122 ITSSNKKPILDVTKPKLAPL--NEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNAL 179
++K L+ +L E G E ++ + + ++ E+L + L T A
Sbjct: 1732 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE 1791
Query: 180 DEKSKLEKALQDLQLDQGNQKDFIKAQ---DLSNLENTVAALKSEFQKTLNDKTENQKSL 236
+ +LE+ ++L+ + +K++ ++ LE +A L+ + ++ +K KSL
Sbjct: 1792 SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1851
Query: 237 EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
++ K LL+V+++ MAE+ KE K N ++K L+++L + E
Sbjct: 1852 KQKDKKLKEILLQVEDERKMAEQ--------------YKEQAEKGNARVKQLKRQLEEAE 1897
Query: 297 PE 298
E
Sbjct: 1898 EE 1899
Score = 40.4 bits (93), Expect = 0.002
Identities = 66/276 (23%), Positives = 125/276 (45%), Gaps = 24/276 (8%)
Query: 23 SKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVL 82
+++ L+L+ V + + K +L ++ +D+ + L+ + ++ E I+ TN+
Sbjct: 972 ARQKLQLEKVTA---EAKIKKLEDEILVMDDQNNKLSKERKLLE-----ERISDLTTNLA 1023
Query: 83 LLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLN 142
+ K K ++ ISELE R E+ + E ++ + D + ++A L
Sbjct: 1024 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE-QIADL- 1081
Query: 143 EGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDF 202
+ AEL ++ + +EE + +RL Q NAL + +LE + DLQ D +++
Sbjct: 1082 QAQIAEL-KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 203 IKAQDLS--NLENTVAALKSEFQKTLNDKTENQKSL---EENLATAKHDLLRVQEQLHMA 257
+ +L + ALK+E + TL D T Q+ L E T L + + H A
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTL-DSTATQQELRAKREQEVTVLKKALDEETRSHEA 1199
Query: 258 E-KELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRL 292
+ +E+ +K Q E LT++ +Q K + L
Sbjct: 1200 QVQEMRQKHAQAV------EELTEQLEQFKRAKANL 1229
Score = 40.4 bits (93), Expect = 0.002
Identities = 58/215 (26%), Positives = 95/215 (44%), Gaps = 28/215 (13%)
Query: 104 ELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGG--TAELLNKEILR-LQEE 160
E + E+ Q+ E E + + K L+V L E + N+E R LQ +
Sbjct: 1545 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1604
Query: 161 NEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKS 220
+ ++ L+ Q A K KLE L+DL+L Q + + + + L A +K
Sbjct: 1605 LHEYETELEDERKQRALAAAAKKKLEGDLKDLEL-QADSAIKGREEAIKQLRKLQAQMK- 1662
Query: 221 EFQKTLNDKTENQKSLEENLATAKH----------DLLRVQEQLHMAEK-------ELEK 263
+FQ+ L D + S +E ATAK DL+++QE L AE+ E E+
Sbjct: 1663 DFQRELEDA---RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1719
Query: 264 KFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPE 298
++ A+ + + L D+ + L R+AQ E E
Sbjct: 1720 LAEELASSLSGRNAL---QDEKRRLEARIAQLEEE 1751
Score = 35.4 bits (80), Expect = 0.061
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 36/172 (20%)
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQL-----DQGNQKDFIK 204
L+K L++EN L L+ + +K KLE +Q+LQ ++ + K
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1288
Query: 205 AQDLSN------------------LENTVAALKSEFQKT---LNDKTENQKSLEENLATA 243
L N L VA+L S+ Q T L ++T + ++ L
Sbjct: 1289 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1348
Query: 244 KHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQY 295
+ + +Q+QL ++E+E K +N++ ++ N Q+ D +K+L +
Sbjct: 1349 EEERNSLQDQL---DEEMEAK-------QNLERHISTLNIQLSDSKKKLQDF 1390
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 53.5 bits (127), Expect = 2e-07
Identities = 69/302 (22%), Positives = 128/302 (42%), Gaps = 43/302 (14%)
Query: 22 RSKRGLRLKTVDSCFQDLKESRLVEDTFTI--DEVSEVLNGLQAVVHS---EVES----- 71
R +R L DLK+ L D+ +E + L LQA + E+E
Sbjct: 1616 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1675
Query: 72 -ELINTAYTNVLLLRQLFAQAEKWYLKLQTDIS---------ELENRELLEQVAEFEKAE 121
E+ TA N + L A ++LQ D++ +LE EL E++A
Sbjct: 1676 DEIFATAKENEKKAKSLEADL----MQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1731
Query: 122 ITSSNKKPILDVTKPKLAPL--NEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNAL 179
++K L+ +L E G E ++ + + ++ E+L + L T A
Sbjct: 1732 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE 1791
Query: 180 DEKSKLEKALQDLQLDQGNQKDFIKAQ---DLSNLENTVAALKSEFQKTLNDKTENQKSL 236
+ +LE+ ++L+ + +K++ ++ LE +A L+ + ++ +K KSL
Sbjct: 1792 SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1851
Query: 237 EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
++ K LL+V+++ MAE+ KE K N ++K L+++L + E
Sbjct: 1852 KQKDKKLKEILLQVEDERKMAEQ--------------YKEQAEKGNARVKQLKRQLEEAE 1897
Query: 297 PE 298
E
Sbjct: 1898 EE 1899
Score = 40.4 bits (93), Expect = 0.002
Identities = 66/276 (23%), Positives = 125/276 (45%), Gaps = 24/276 (8%)
Query: 23 SKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVL 82
+++ L+L+ V + + K +L ++ +D+ + L+ + ++ E I+ TN+
Sbjct: 972 ARQKLQLEKVTA---EAKIKKLEDEILVMDDQNNKLSKERKLLE-----ERISDLTTNLA 1023
Query: 83 LLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLN 142
+ K K ++ ISELE R E+ + E ++ + D + ++A L
Sbjct: 1024 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE-QIADL- 1081
Query: 143 EGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDF 202
+ AEL ++ + +EE + +RL Q NAL + +LE + DLQ D +++
Sbjct: 1082 QAQIAEL-KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1140
Query: 203 IKAQDLS--NLENTVAALKSEFQKTLNDKTENQKSL---EENLATAKHDLLRVQEQLHMA 257
+ +L + ALK+E + TL D T Q+ L E T L + + H A
Sbjct: 1141 RNKAEKQKRDLGEELEALKTELEDTL-DSTATQQELRAKREQEVTVLKKALDEETRSHEA 1199
Query: 258 E-KELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRL 292
+ +E+ +K Q E LT++ +Q K + L
Sbjct: 1200 QVQEMRQKHAQAV------EELTEQLEQFKRAKANL 1229
Score = 40.4 bits (93), Expect = 0.002
Identities = 58/215 (26%), Positives = 95/215 (44%), Gaps = 28/215 (13%)
Query: 104 ELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGG--TAELLNKEILR-LQEE 160
E + E+ Q+ E E + + K L+V L E + N+E R LQ +
Sbjct: 1545 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1604
Query: 161 NEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKS 220
+ ++ L+ Q A K KLE L+DL+L Q + + + + L A +K
Sbjct: 1605 LHEYETELEDERKQRALAAAAKKKLEGDLKDLEL-QADSAIKGREEAIKQLRKLQAQMK- 1662
Query: 221 EFQKTLNDKTENQKSLEENLATAKH----------DLLRVQEQLHMAEK-------ELEK 263
+FQ+ L D + S +E ATAK DL+++QE L AE+ E E+
Sbjct: 1663 DFQRELEDA---RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1719
Query: 264 KFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPE 298
++ A+ + + L D+ + L R+AQ E E
Sbjct: 1720 LAEELASSLSGRNAL---QDEKRRLEARIAQLEEE 1751
Score = 35.4 bits (80), Expect = 0.061
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 36/172 (20%)
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQL-----DQGNQKDFIK 204
L+K L++EN L L+ + +K KLE +Q+LQ ++ + K
Sbjct: 1229 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1288
Query: 205 AQDLSN------------------LENTVAALKSEFQKT---LNDKTENQKSLEENLATA 243
L N L VA+L S+ Q T L ++T + ++ L
Sbjct: 1289 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1348
Query: 244 KHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQY 295
+ + +Q+QL ++E+E K +N++ ++ N Q+ D +K+L +
Sbjct: 1349 EEERNSLQDQL---DEEMEAK-------QNLERHISTLNIQLSDSKKKLQDF 1390
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 53.5 bits (127), Expect = 2e-07
Identities = 69/302 (22%), Positives = 128/302 (42%), Gaps = 43/302 (14%)
Query: 22 RSKRGLRLKTVDSCFQDLKESRLVEDTFTI--DEVSEVLNGLQAVVHS---EVES----- 71
R +R L DLK+ L D+ +E + L LQA + E+E
Sbjct: 1609 RKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASR 1668
Query: 72 -ELINTAYTNVLLLRQLFAQAEKWYLKLQTDIS---------ELENRELLEQVAEFEKAE 121
E+ TA N + L A ++LQ D++ +LE EL E++A
Sbjct: 1669 DEIFATAKENEKKAKSLEADL----MQLQEDLAAAERARKQADLEKEELAEELASSLSGR 1724
Query: 122 ITSSNKKPILDVTKPKLAPL--NEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNAL 179
++K L+ +L E G E ++ + + ++ E+L + L T A
Sbjct: 1725 NALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNE 1784
Query: 180 DEKSKLEKALQDLQLDQGNQKDFIKAQ---DLSNLENTVAALKSEFQKTLNDKTENQKSL 236
+ +LE+ ++L+ + +K++ ++ LE +A L+ + ++ +K KSL
Sbjct: 1785 SARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSL 1844
Query: 237 EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
++ K LL+V+++ MAE+ KE K N ++K L+++L + E
Sbjct: 1845 KQKDKKLKEILLQVEDERKMAEQ--------------YKEQAEKGNARVKQLKRQLEEAE 1890
Query: 297 PE 298
E
Sbjct: 1891 EE 1892
Score = 40.4 bits (93), Expect = 0.002
Identities = 66/276 (23%), Positives = 125/276 (45%), Gaps = 24/276 (8%)
Query: 23 SKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVL 82
+++ L+L+ V + + K +L ++ +D+ + L+ + ++ E I+ TN+
Sbjct: 965 ARQKLQLEKVTA---EAKIKKLEDEILVMDDQNNKLSKERKLLE-----ERISDLTTNLA 1016
Query: 83 LLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLN 142
+ K K ++ ISELE R E+ + E ++ + D + ++A L
Sbjct: 1017 EEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE-QIADL- 1074
Query: 143 EGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDF 202
+ AEL ++ + +EE + +RL Q NAL + +LE + DLQ D +++
Sbjct: 1075 QAQIAEL-KMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAA 1133
Query: 203 IKAQDLS--NLENTVAALKSEFQKTLNDKTENQKSL---EENLATAKHDLLRVQEQLHMA 257
+ +L + ALK+E + TL D T Q+ L E T L + + H A
Sbjct: 1134 RNKAEKQKRDLGEELEALKTELEDTL-DSTATQQELRAKREQEVTVLKKALDEETRSHEA 1192
Query: 258 E-KELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRL 292
+ +E+ +K Q E LT++ +Q K + L
Sbjct: 1193 QVQEMRQKHAQAV------EELTEQLEQFKRAKANL 1222
Score = 40.4 bits (93), Expect = 0.002
Identities = 58/215 (26%), Positives = 95/215 (44%), Gaps = 28/215 (13%)
Query: 104 ELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGG--TAELLNKEILR-LQEE 160
E + E+ Q+ E E + + K L+V L E + N+E R LQ +
Sbjct: 1538 ETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQ 1597
Query: 161 NEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKS 220
+ ++ L+ Q A K KLE L+DL+L Q + + + + L A +K
Sbjct: 1598 LHEYETELEDERKQRALAAAAKKKLEGDLKDLEL-QADSAIKGREEAIKQLRKLQAQMK- 1655
Query: 221 EFQKTLNDKTENQKSLEENLATAKH----------DLLRVQEQLHMAEK-------ELEK 263
+FQ+ L D + S +E ATAK DL+++QE L AE+ E E+
Sbjct: 1656 DFQRELEDA---RASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 1712
Query: 264 KFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPE 298
++ A+ + + L D+ + L R+AQ E E
Sbjct: 1713 LAEELASSLSGRNAL---QDEKRRLEARIAQLEEE 1744
Score = 35.4 bits (80), Expect = 0.061
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 36/172 (20%)
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQL-----DQGNQKDFIK 204
L+K L++EN L L+ + +K KLE +Q+LQ ++ + K
Sbjct: 1222 LDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281
Query: 205 AQDLSN------------------LENTVAALKSEFQKT---LNDKTENQKSLEENLATA 243
L N L VA+L S+ Q T L ++T + ++ L
Sbjct: 1282 VHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQL 1341
Query: 244 KHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQY 295
+ + +Q+QL ++E+E K +N++ ++ N Q+ D +K+L +
Sbjct: 1342 EEERNSLQDQL---DEEMEAK-------QNLERHISTLNIQLSDSKKKLQDF 1383
>gi|147905592 coiled-coil domain containing 102B [Homo sapiens]
Length = 513
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/196 (25%), Positives = 95/196 (48%), Gaps = 19/196 (9%)
Query: 107 NRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILR-----LQEEN 161
N E+ E ++ + ++K ++ + +L L T+E +EIL L+ EN
Sbjct: 321 NDEMQELSGNIKEESKSQNSKDRVICELRAELERLQAENTSEWDKREILEREKQGLEREN 380
Query: 162 EKLKSRLKTIEIQATNALDEKSKLEKALQ--DLQLDQGNQKDFIKAQDLSNLENTVAALK 219
+LK ++K +E LD+K++L Q D ++ Q + ++ K Q+L NL++ L
Sbjct: 381 RRLKIQVKEME----ELLDKKNRLSANSQSPDFKMSQIDLQE--KNQELLNLQHAYYKLN 434
Query: 220 SEFQKTLNDKTENQKSLEENLATAKHDLLRVQE---QLHMAEKELEKKFQQTAAYRNMKE 276
++Q + + T +++N A K LRV+E L+ E EL+ Q R ++
Sbjct: 435 RQYQANIAELTHANNRVDQNEAEVKKLRLRVEELKQGLNQKEDELDDSLNQ---IRKLQR 491
Query: 277 ILTKKNDQIKDLRKRL 292
L ++ ++ ++L L
Sbjct: 492 SLDEEKERNENLETEL 507
>gi|148233522 coiled-coil domain containing 102B [Homo sapiens]
Length = 513
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/196 (25%), Positives = 95/196 (48%), Gaps = 19/196 (9%)
Query: 107 NRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILR-----LQEEN 161
N E+ E ++ + ++K ++ + +L L T+E +EIL L+ EN
Sbjct: 321 NDEMQELSGNIKEESKSQNSKDRVICELRAELERLQAENTSEWDKREILEREKQGLEREN 380
Query: 162 EKLKSRLKTIEIQATNALDEKSKLEKALQ--DLQLDQGNQKDFIKAQDLSNLENTVAALK 219
+LK ++K +E LD+K++L Q D ++ Q + ++ K Q+L NL++ L
Sbjct: 381 RRLKIQVKEME----ELLDKKNRLSANSQSPDFKMSQIDLQE--KNQELLNLQHAYYKLN 434
Query: 220 SEFQKTLNDKTENQKSLEENLATAKHDLLRVQE---QLHMAEKELEKKFQQTAAYRNMKE 276
++Q + + T +++N A K LRV+E L+ E EL+ Q R ++
Sbjct: 435 RQYQANIAELTHANNRVDQNEAEVKKLRLRVEELKQGLNQKEDELDDSLNQ---IRKLQR 491
Query: 277 ILTKKNDQIKDLRKRL 292
L ++ ++ ++L L
Sbjct: 492 SLDEEKERNENLETEL 507
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 52.8 bits (125), Expect = 4e-07
Identities = 55/198 (27%), Positives = 83/198 (41%), Gaps = 21/198 (10%)
Query: 104 ELENRELLE-QVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLN-KEILRLQEEN 161
E NR+ LE ++AE K + ++ +LA LNE A L KE+ L+++N
Sbjct: 226 ERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKN 285
Query: 162 EKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSE 221
E L RL Q + EKS++++ + L + G DLS A+ +
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENG---------DLSFKLREFASHLQQ 336
Query: 222 FQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKK 281
Q LN+ TE A + L Q QL EKEL Q EIL K
Sbjct: 337 LQDALNELTEEHSK-------ATQEWLEKQAQL---EKELSAALQDKKCLEEKNEILQGK 386
Query: 282 NDQIKDLRKRLAQYEPED 299
Q+++ +L P++
Sbjct: 387 LSQLEEHLSQLQDNPPQE 404
Score = 38.5 bits (88), Expect = 0.007
Identities = 35/147 (23%), Positives = 63/147 (42%), Gaps = 10/147 (6%)
Query: 143 EGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDF 202
EG ++L +E R QEE +KL ++++ +E+ + +L K L D +Q
Sbjct: 1513 EGAKVKVL-EERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD-----SDQASK 1566
Query: 203 IKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELE 262
++ Q L ++ + E Q+ E Q L + A+H L Q+ A+ +
Sbjct: 1567 VQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKL----QMEKAKTHYD 1622
Query: 263 KKFQQTAAYRNMKEILTKKNDQIKDLR 289
K QQ + L + + K+LR
Sbjct: 1623 AKKQQNQELQEQLRSLEQLQKENKELR 1649
Score = 37.7 bits (86), Expect = 0.012
Identities = 54/239 (22%), Positives = 104/239 (43%), Gaps = 21/239 (8%)
Query: 69 VESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKK 128
+E EL V L + A AE ++Q + ++ REL A++E A++ ++
Sbjct: 1465 LEVELDQAREKYVQELAAVRADAETRLAEVQRE-AQSTARELEVMTAKYEGAKVKVLEER 1523
Query: 129 PILDVTKPKLAPLNEG---------GTAELLNKEILRLQEENEKLKSRLKTIEIQATNAL 179
+ KL E E L+K++ + ++ + +LK ++ Q +
Sbjct: 1524 QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQ 1583
Query: 180 DEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQ-KSLEE 238
E +L+ L +LQ Q +QK+ +A + L+ A + +K N + + Q +SLE+
Sbjct: 1584 QEAQRLQAQLNELQA-QLSQKE--QAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQ 1640
Query: 239 ------NLATAKHDLLRVQEQLHMAEKELEKKFQQ-TAAYRNMKEILTKKNDQIKDLRK 290
L L +Q + KE E+ + TA R+++ + + Q++DL K
Sbjct: 1641 LQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGK 1699
Score = 36.2 bits (82), Expect = 0.036
Identities = 41/179 (22%), Positives = 86/179 (48%), Gaps = 23/179 (12%)
Query: 141 LNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQ----ATNALDEKSKLEKALQDLQLDQ 196
L + G ++ L + ++ E+++KL+ RL+ ++ + + A + S L + +Q L+ +
Sbjct: 1242 LEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEA 1301
Query: 197 GNQKDFIK--AQDLSNLENTVAALKSE--------FQK-----TLNDKTENQKSLEENLA 241
Q+ + Q+L++ L E FQK TL + + ++L L
Sbjct: 1302 EKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELL 1361
Query: 242 TAKHDLLRVQEQLHMAEKELEKKFQQT--AAYRNMKEILTKKND--QIKDLRKRLAQYE 296
AKH ++Q + AEK ++ +Q+ AA E+L + + ++ LR+++A+ E
Sbjct: 1362 PAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQE 1420
Score = 33.5 bits (75), Expect = 0.23
Identities = 49/215 (22%), Positives = 92/215 (42%), Gaps = 27/215 (12%)
Query: 68 EVESELINTAYTNVLLLRQLFAQAEKWYLKLQT--DISELENRELLEQVAEFEKAEITSS 125
+V +E ++A T+V ++ A+ + +LQ + + E E QVAE E ++ S
Sbjct: 625 QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELE-LQLRSE 683
Query: 126 NKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLK----TIEIQATNALDE 181
+K E + +E +LQE+ + LK LK ++E + A D
Sbjct: 684 QQKAT---------------EKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADA 728
Query: 182 KSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLA 241
+ ++ + +L+ + + + K ++ LE A K + L E ++ E L
Sbjct: 729 LEEQQRCISELKAETRSLVEQHK-RERKELEEERAGRKG-LEARLQQLGEAHQAETEVL- 785
Query: 242 TAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKE 276
+ +L H AE E E+ ++ AA+R E
Sbjct: 786 --RRELAEAMAAQHTAESECEQLVKEVAAWRERYE 818
Score = 33.1 bits (74), Expect = 0.31
Identities = 54/238 (22%), Positives = 105/238 (44%), Gaps = 26/238 (10%)
Query: 42 SRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTD 101
S L TI + + L GL+ E +++L T + L Q E+ L +
Sbjct: 505 SELTTLNATIQQQDQELAGLKQQA-KEKQAQLAQTLQQQEQASQGLRHQVEQ----LSSS 559
Query: 102 ISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTA----ELLNKE---- 153
+ + E + L++VAE ++A + + + + + A L E A E L KE
Sbjct: 560 LKQKEQQ--LKEVAEKQEAT-RQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAK 616
Query: 154 ILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQ--LDQGNQKDFIKAQDLSNL 211
+ LQ++ + + + T A EK++L + +++LQ ++ Q+ ++ L
Sbjct: 617 LEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL 676
Query: 212 ENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTA 269
E L+SE QK TE ++ +E + L ++E L + + LE++ ++ A
Sbjct: 677 E---LQLRSEQQKA----TEKERVAQEK-DQLQEQLQALKESLKVTKGSLEEEKRRAA 726
Score = 31.6 bits (70), Expect = 0.89
Identities = 52/254 (20%), Positives = 110/254 (43%), Gaps = 42/254 (16%)
Query: 55 SEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDI------SELENR 108
+ + LQ V EV ++ + ++ L++ A K +L+T + E +R
Sbjct: 879 ANLARALQQVQEKEVRAQKLAD---DLSTLQEKMAATSKEVARLETLVRKAGEQQETASR 935
Query: 109 ELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRL 168
EL+++ A + +++P + + + + +E ++ E E+L++ L
Sbjct: 936 ELVKEPAR-------AGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL 988
Query: 169 KTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLND 228
+ Q +E+ + E+ + L ++G + DL+ + A L+ Q LN+
Sbjct: 989 MESQGQQQ---EERGQQEREVARLTQERGRAQ-----ADLALEKAARAELEMRLQNALNE 1040
Query: 229 KTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQ---- 284
+ +L+E LA A + EK E K Q+ A R ++ K+ ++
Sbjct: 1041 QRVEFATLQEALAHA------------LTEK--EGKDQELAKLRGLEAAQIKELEELRQT 1086
Query: 285 IKDLRKRLAQYEPE 298
+K L+++LA+ E E
Sbjct: 1087 VKQLKEQLAKKEKE 1100
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 51.6 bits (122), Expect = 8e-07
Identities = 49/194 (25%), Positives = 87/194 (44%), Gaps = 18/194 (9%)
Query: 98 LQTDISELENRELLEQV--AEFEKAEITSSNKK-----PILDVTKPKLAPLNEGGTAELL 150
LQ D+ + E E+ E + AE + E+ S K L + KL+ LNE + L
Sbjct: 694 LQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKL 753
Query: 151 --NKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDL 208
N+ + +L+EE L+ R + E +AT A +E+ +LE +L+L+Q + Q L
Sbjct: 754 DLNRLVAQLEEEKSALQGRQRQAEQEATVAREEQERLE----ELRLEQE-----VARQGL 804
Query: 209 SNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQT 268
+ ++ L + L+E LA L +++L A +E +++ +
Sbjct: 805 EGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL 864
Query: 269 AAYRNMKEILTKKN 282
KE L K++
Sbjct: 865 ERAAREKEALAKEH 878
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/224 (25%), Positives = 102/224 (45%), Gaps = 28/224 (12%)
Query: 97 KLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVT---KPKLAPLNEGGTAEL---- 149
+LQ +++L +R+L + E E+A + + L+ K LA + G +L
Sbjct: 831 QLQEQLAQL-SRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAE 889
Query: 150 -----LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQ-------- 196
L++E RL+ E E L+ L ++ Q + +LE Q L L +
Sbjct: 890 REGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELA 949
Query: 197 GNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHM 256
G ++ I Q+ ++L+ + A QK + + E Q SL E A + DL R+Q +
Sbjct: 950 GLRQQIIATQEKASLDKELMA-----QKLVQAEREAQASLREQRAAHEEDLQRLQREKEA 1004
Query: 257 AEKEL--EKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPE 298
A +EL E+ Q+ R +E+L + + ++L + +A + E
Sbjct: 1005 AWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQE 1048
Score = 43.5 bits (101), Expect = 2e-04
Identities = 50/222 (22%), Positives = 96/222 (43%), Gaps = 38/222 (17%)
Query: 103 SELENRELLEQVAEFEKA------EITSSNKK--------PILDVTKPKLAPLNEGGTAE 148
SE E R L+QVA E++ E+ +S +K L+ K +L + + +
Sbjct: 1591 SERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESR 1650
Query: 149 LLNKEILRLQEENEKLKSRL--KTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQ 206
+ E+ R E E +SRL E QA D L++ + D ++ G + ++
Sbjct: 1651 TVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERL 1710
Query: 207 D--LSNLENTVAALKSEFQ----------KTLNDKTENQKSLEENLATAKHDLLRVQEQL 254
+ L+ +E + AL+ + + +LN + L++ L +HD +QE+L
Sbjct: 1711 NGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERL 1770
Query: 255 HMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
A + L + +Q+++ +Q++ LR +A E
Sbjct: 1771 DAARQALSEARKQSSSL----------GEQVQTLRGEVADLE 1802
Score = 32.0 bits (71), Expect = 0.68
Identities = 52/233 (22%), Positives = 96/233 (41%), Gaps = 36/233 (15%)
Query: 89 AQAEKWYLKLQTDISELENRELLEQVAE-----FEKAEITSSNKKPILDVTK-------P 136
A+A++ L L+T I LE+ L ++ + A+ITS VT+ P
Sbjct: 6 ARAQEVELTLETVIQTLESSVLCQEKGLGARDLAQDAQITSLPALIREIVTRNLSQPESP 65
Query: 137 KLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKL--------EKA 188
L P E + +L LQEEN+ L+ L +E + E+ +L E+
Sbjct: 66 VLLPATEMAS-------LLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERL 118
Query: 189 LQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLL 248
Q L+L+ G ++ Q+ L L+ + Q+ ++ +E +
Sbjct: 119 EQALRLEPGE----LETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQ 174
Query: 249 RVQEQLHMAEK---ELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPE 298
R+Q ++ +K ELE++ + + + + ++ Q DL L + E E
Sbjct: 175 RLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQ--DLESALIRLEEE 225
Score = 31.2 bits (69), Expect = 1.2
Identities = 49/239 (20%), Positives = 99/239 (41%), Gaps = 39/239 (16%)
Query: 85 RQLFAQAEKWYLKLQTDISEL------ENRELLEQVAEFEKAE-----ITSSNKKPILDV 133
R+L A+ + +LQ + EL E EL E++A ++ + S K+ L +
Sbjct: 1007 RELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSL 1066
Query: 134 TKPKLAPLNEG--GTAELLNKEILRLQEENEKLKSRLK----TIEIQATNALDEKSKLEK 187
+ + L+E GT L L ++ + +SR + T+ + D +++ E+
Sbjct: 1067 KESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREE 1126
Query: 188 A----------LQDLQLDQGNQKD--FIKAQDLSN----LENTVAALKSEF---QKTLND 228
A LQ+ D G Q+D +A++L LE+ L+ E Q+ L +
Sbjct: 1127 AAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 1186
Query: 229 KTENQKSLEENLATAKHDL---LRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQ 284
E ++ + + L + +E L + +EL ++ + R ++ + +Q
Sbjct: 1187 SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQ 1245
Score = 28.5 bits (62), Expect = 7.5
Identities = 22/124 (17%), Positives = 57/124 (45%), Gaps = 15/124 (12%)
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLS 209
L K++ + E L+ +L+ + + A+ ++ +Q L+ + + +++ S
Sbjct: 552 LRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLR-----SANELLSREKS 606
Query: 210 NLENTVAALKSEFQKTLNDKTENQKS----------LEENLATAKHDLLRVQEQLHMAEK 259
NL +++ + + ++ ++ + Q + LEE A D RV+ +L + +
Sbjct: 607 NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHR 666
Query: 260 ELEK 263
+LE+
Sbjct: 667 QLEQ 670
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 51.6 bits (122), Expect = 8e-07
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 19/192 (9%)
Query: 112 EQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTI 171
E+ FEK + + D K ++ AE + + + R+ +E K S L +
Sbjct: 596 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMKEAMNRMIDELNKQVSELSQL 654
Query: 172 EIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL-----ENTVAALKSEFQKTL 226
+A L++ K K+L+D+ + ++ + K L+N+ E+ ++ +KS++ K L
Sbjct: 655 YKEAQAELEDYRK-RKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 713
Query: 227 NDKTENQKSL----EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKN 282
N+ T+ ++ + E +++ +H L+V L A KE+E+K N+KE L K
Sbjct: 714 NELTQLKQLVDAQKENSVSITEH--LQVITTLRTAAKEMEEKIS------NLKEHLASKE 765
Query: 283 DQIKDLRKRLAQ 294
++ L K+L +
Sbjct: 766 VEVAKLEKQLLE 777
Score = 32.3 bits (72), Expect = 0.52
Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)
Query: 147 AELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQ 206
AEL+ + E + L +LK + + A+ E ++K ++ + + ++
Sbjct: 467 AELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFH 526
Query: 207 DLSNLENTVAALKSEFQKTLNDKTENQ---KSLEENLATAKHDLL---RVQEQLHM---- 256
+L E + LK + Q L + N+ + LEE L + + V+E M
Sbjct: 527 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 586
Query: 257 ---AEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 299
E ++K Y+ +E + K D +K + A E ED
Sbjct: 587 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAED 632
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 51.6 bits (122), Expect = 8e-07
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 19/192 (9%)
Query: 112 EQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTI 171
E+ FEK + + D K ++ AE + + + R+ +E K S L +
Sbjct: 585 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMKEAMNRMIDELNKQVSELSQL 643
Query: 172 EIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL-----ENTVAALKSEFQKTL 226
+A L++ K K+L+D+ + ++ + K L+N+ E+ ++ +KS++ K L
Sbjct: 644 YKEAQAELEDYRK-RKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 702
Query: 227 NDKTENQKSL----EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKN 282
N+ T+ ++ + E +++ +H L+V L A KE+E+K N+KE L K
Sbjct: 703 NELTQLKQLVDAQKENSVSITEH--LQVITTLRTAAKEMEEKIS------NLKEHLASKE 754
Query: 283 DQIKDLRKRLAQ 294
++ L K+L +
Sbjct: 755 VEVAKLEKQLLE 766
Score = 32.3 bits (72), Expect = 0.52
Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)
Query: 147 AELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQ 206
AEL+ + E + L +LK + + A+ E ++K ++ + + ++
Sbjct: 456 AELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFH 515
Query: 207 DLSNLENTVAALKSEFQKTLNDKTENQ---KSLEENLATAKHDLL---RVQEQLHM---- 256
+L E + LK + Q L + N+ + LEE L + + V+E M
Sbjct: 516 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 575
Query: 257 ---AEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 299
E ++K Y+ +E + K D +K + A E ED
Sbjct: 576 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAED 621
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 51.6 bits (122), Expect = 8e-07
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 19/192 (9%)
Query: 112 EQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTI 171
E+ FEK + + D K ++ AE + + + R+ +E K S L +
Sbjct: 564 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMKEAMNRMIDELNKQVSELSQL 622
Query: 172 EIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL-----ENTVAALKSEFQKTL 226
+A L++ K K+L+D+ + ++ + K L+N+ E+ ++ +KS++ K L
Sbjct: 623 YKEAQAELEDYRK-RKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 681
Query: 227 NDKTENQKSL----EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKN 282
N+ T+ ++ + E +++ +H L+V L A KE+E+K N+KE L K
Sbjct: 682 NELTQLKQLVDAQKENSVSITEH--LQVITTLRTAAKEMEEKIS------NLKEHLASKE 733
Query: 283 DQIKDLRKRLAQ 294
++ L K+L +
Sbjct: 734 VEVAKLEKQLLE 745
Score = 32.3 bits (72), Expect = 0.52
Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)
Query: 147 AELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQ 206
AEL+ + E + L +LK + + A+ E ++K ++ + + ++
Sbjct: 435 AELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFH 494
Query: 207 DLSNLENTVAALKSEFQKTLNDKTENQ---KSLEENLATAKHDLL---RVQEQLHM---- 256
+L E + LK + Q L + N+ + LEE L + + V+E M
Sbjct: 495 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 554
Query: 257 ---AEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 299
E ++K Y+ +E + K D +K + A E ED
Sbjct: 555 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAED 600
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 51.6 bits (122), Expect = 8e-07
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 19/192 (9%)
Query: 112 EQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTI 171
E+ FEK + + D K ++ AE + + + R+ +E K S L +
Sbjct: 593 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMKEAMNRMIDELNKQVSELSQL 651
Query: 172 EIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL-----ENTVAALKSEFQKTL 226
+A L++ K K+L+D+ + ++ + K L+N+ E+ ++ +KS++ K L
Sbjct: 652 YKEAQAELEDYRK-RKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 227 NDKTENQKSL----EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKN 282
N+ T+ ++ + E +++ +H L+V L A KE+E+K N+KE L K
Sbjct: 711 NELTQLKQLVDAQKENSVSITEH--LQVITTLRTAAKEMEEKIS------NLKEHLASKE 762
Query: 283 DQIKDLRKRLAQ 294
++ L K+L +
Sbjct: 763 VEVAKLEKQLLE 774
Score = 32.3 bits (72), Expect = 0.52
Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)
Query: 147 AELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQ 206
AEL+ + E + L +LK + + A+ E ++K ++ + + ++
Sbjct: 464 AELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFH 523
Query: 207 DLSNLENTVAALKSEFQKTLNDKTENQ---KSLEENLATAKHDLL---RVQEQLHM---- 256
+L E + LK + Q L + N+ + LEE L + + V+E M
Sbjct: 524 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 583
Query: 257 ---AEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 299
E ++K Y+ +E + K D +K + A E ED
Sbjct: 584 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAED 629
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 51.6 bits (122), Expect = 8e-07
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 19/192 (9%)
Query: 112 EQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTI 171
E+ FEK + + D K ++ AE + + + R+ +E K S L +
Sbjct: 593 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMKEAMNRMIDELNKQVSELSQL 651
Query: 172 EIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL-----ENTVAALKSEFQKTL 226
+A L++ K K+L+D+ + ++ + K L+N+ E+ ++ +KS++ K L
Sbjct: 652 YKEAQAELEDYRK-RKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 227 NDKTENQKSL----EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKN 282
N+ T+ ++ + E +++ +H L+V L A KE+E+K N+KE L K
Sbjct: 711 NELTQLKQLVDAQKENSVSITEH--LQVITTLRTAAKEMEEKIS------NLKEHLASKE 762
Query: 283 DQIKDLRKRLAQ 294
++ L K+L +
Sbjct: 763 VEVAKLEKQLLE 774
Score = 32.3 bits (72), Expect = 0.52
Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)
Query: 147 AELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQ 206
AEL+ + E + L +LK + + A+ E ++K ++ + + ++
Sbjct: 464 AELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFH 523
Query: 207 DLSNLENTVAALKSEFQKTLNDKTENQ---KSLEENLATAKHDLL---RVQEQLHM---- 256
+L E + LK + Q L + N+ + LEE L + + V+E M
Sbjct: 524 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 583
Query: 257 ---AEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 299
E ++K Y+ +E + K D +K + A E ED
Sbjct: 584 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAED 629
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 51.6 bits (122), Expect = 8e-07
Identities = 47/192 (24%), Positives = 93/192 (48%), Gaps = 19/192 (9%)
Query: 112 EQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTI 171
E+ FEK + + D K ++ AE + + + R+ +E K S L +
Sbjct: 593 EKAFLFEKYQEAQEEIMKLKDTLKSQMTQ-EASDEAEDMKEAMNRMIDELNKQVSELSQL 651
Query: 172 EIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL-----ENTVAALKSEFQKTL 226
+A L++ K K+L+D+ + ++ + K L+N+ E+ ++ +KS++ K L
Sbjct: 652 YKEAQAELEDYRK-RKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVL 710
Query: 227 NDKTENQKSL----EENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKN 282
N+ T+ ++ + E +++ +H L+V L A KE+E+K N+KE L K
Sbjct: 711 NELTQLKQLVDAQKENSVSITEH--LQVITTLRTAAKEMEEKIS------NLKEHLASKE 762
Query: 283 DQIKDLRKRLAQ 294
++ L K+L +
Sbjct: 763 VEVAKLEKQLLE 774
Score = 32.3 bits (72), Expect = 0.52
Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 13/166 (7%)
Query: 147 AELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQ 206
AEL+ + E + L +LK + + A+ E ++K ++ + + ++
Sbjct: 464 AELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFH 523
Query: 207 DLSNLENTVAALKSEFQKTLNDKTENQ---KSLEENLATAKHDLL---RVQEQLHM---- 256
+L E + LK + Q L + N+ + LEE L + + V+E M
Sbjct: 524 ELRVTEEEINVLKQDLQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSY 583
Query: 257 ---AEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPED 299
E ++K Y+ +E + K D +K + A E ED
Sbjct: 584 CSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAED 629
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 51.2 bits (121), Expect = 1e-06
Identities = 47/147 (31%), Positives = 70/147 (47%), Gaps = 9/147 (6%)
Query: 142 NEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKD 201
NE E+ KE R++ E E+L RLK IE Q A +K E+ + L+LDQ ++
Sbjct: 325 NEKKKREIAEKEKERIEREKEELMERLKQIEEQTIKA--QKELEEQTRKALELDQERKRA 382
Query: 202 FIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLA--TAKHDLLRVQEQLHMAEK 259
+A+ L KS K D+ +NQ+ L LA TAK LL ++ +K
Sbjct: 383 KEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKK----KK 438
Query: 260 ELEKKFQQTAAYRNMKEILTKKNDQIK 286
E E Q A+ +E L K +++K
Sbjct: 439 EEEATEWQHKAFA-AQEDLEKTKEELK 464
Score = 46.2 bits (108), Expect = 3e-05
Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 8/149 (5%)
Query: 150 LNKEILRLQEENEKLKSRLK---TIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQ 206
+NK IL L N +L R + TIE+Q A + K +K L+ QL+ +K I +
Sbjct: 276 INKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLENEKKKREIAEK 335
Query: 207 DLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQ 266
+ +E L ++ + QK LEE A L + ++ A++E E+ +
Sbjct: 336 EKERIEREKEELMERLKQIEEQTIKAQKELEEQTRKA----LELDQERKRAKEEAERLEK 391
Query: 267 QTAAYRNMKEILTKK-NDQIKDLRKRLAQ 294
+ A K + K+ DQ+K+ + A+
Sbjct: 392 ERRAAEEAKSAIAKQAADQMKNQEQLAAE 420
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 51.2 bits (121), Expect = 1e-06
Identities = 61/278 (21%), Positives = 123/278 (44%), Gaps = 53/278 (19%)
Query: 36 FQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWY 95
+Q L++ D D +E LQ++ E + E T N+ ++ LF Q
Sbjct: 116 YQGLQQQEAKPDGLVTDSSAE----LQSL---EQQLEEAQTENFNIKQMKDLFEQKAA-- 166
Query: 96 LKLQTDISELENR----ELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAEL-- 149
+L T+I++++++ L + AE + +T K + K L G ++
Sbjct: 167 -QLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAV 225
Query: 150 LNKEILRLQ-----------EENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGN 198
L KE++++Q E+EKLK K ++ Q ++ S+L +L +G
Sbjct: 226 LKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRS-----ELAKGP 280
Query: 199 QKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAE 258
Q+ + Q+L L+++V N+ T+ ++L ENL + D +++
Sbjct: 281 QEVAVYVQELQKLKSSV-----------NELTQKNQTLTENLLKKEQDYTKLE------- 322
Query: 259 KELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
EK +++ + +N++ L +K+ + L+ RL+ E
Sbjct: 323 ---EKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASE 357
Score = 48.5 bits (114), Expect = 7e-06
Identities = 62/264 (23%), Positives = 126/264 (47%), Gaps = 19/264 (7%)
Query: 40 KESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQ 99
KE+ + E + D++S+V + L+ +S+ E E N +L + + K L++Q
Sbjct: 848 KEALMTELSTVKDKLSKVSDSLK---NSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQ 904
Query: 100 TDISELENRELLEQVAEFEKA------EITSSNKKPILDVTKPKLAPLNEGGTAELLNKE 153
+ + E +EL + + + ++A E+ S ++ I K E + L
Sbjct: 905 MENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEE----QQLQGN 960
Query: 154 ILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLEN 213
I L++ +E+ K +++ ++ + A+ +K++LE LQ QL Q Q+ + + +S L+N
Sbjct: 961 INELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQ-QLTQAAQELAAEKEKISVLQN 1019
Query: 214 TVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRN 273
+ F++ +D + L LAT + DL V+E+L +A+++L Q
Sbjct: 1020 NYEKSQETFKQLQSDFYGRESEL---LAT-RQDLKSVEEKLSLAQEDLISNRNQIGNQNK 1075
Query: 274 M-KEILTKKNDQIKDLRKRLAQYE 296
+ +E+ T K +D K+ Q +
Sbjct: 1076 LIQELKTAKATLEQDSAKKEQQLQ 1099
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/148 (25%), Positives = 70/148 (47%), Gaps = 15/148 (10%)
Query: 152 KEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDF-IKAQDLSN 210
++ L L+++ E+L+ ++K +E ++L+ K+ E+ALQDLQ + D ++A +LS
Sbjct: 716 EKYLSLEQKTEELEGQIKKLE---ADSLEVKASKEQALQDLQQQRQLNTDLELRATELSK 772
Query: 211 LENTVAALKSEFQKTLNDKTENQKSL-------EENLATAKHDLLRVQEQLHMAEKELEK 263
+ S + L K+E +S+ EE K D + ++ + +EL
Sbjct: 773 QLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNN 832
Query: 264 KFQQTAA----YRNMKEILTKKNDQIKD 287
+ Q T + KE L + +KD
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKD 860
Score = 32.3 bits (72), Expect = 0.52
Identities = 58/252 (23%), Positives = 100/252 (39%), Gaps = 50/252 (19%)
Query: 72 ELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELEN------RELLEQVAEFEKAEITSS 125
E ++ A +++ R K +L+T + LE ++L E+ + + S
Sbjct: 1054 EKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKS 1113
Query: 126 NKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKS-RLKTIEIQATNALDEKSK 184
K+ L K KLA + E + KEI +L NE+LKS +L++I+ + TN D K
Sbjct: 1114 LKEKELVNEKSKLAEIEEIKCRQ--EKEITKL---NEELKSHKLESIK-EITNLKDAKQL 1167
Query: 185 L--------------------EKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQK 224
L EK Q + DQ +++ L+ +++
Sbjct: 1168 LIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEE-------EELKKEFIEKEAKLHS 1220
Query: 225 TLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQ 284
+ +K K EEN A + + E L +KE + ++ R + E+ Q
Sbjct: 1221 EIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQ------SSQRRVSEL----EKQ 1270
Query: 285 IKDLRKRLAQYE 296
DLR +A E
Sbjct: 1271 TDDLRGEIAVLE 1282
Score = 28.9 bits (63), Expect = 5.8
Identities = 27/122 (22%), Positives = 56/122 (45%), Gaps = 9/122 (7%)
Query: 173 IQATNALDEKSKLEKALQDLQLDQGNQKDF---IKAQDLSNLENTV----AALKSE--FQ 223
+++ + DE K +A+ D D G+ + +K D++ L V A+LK E +
Sbjct: 47 MKSLGSADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYS 106
Query: 224 KTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKND 283
+ L + E + L++ A + +L E++LE+ + + MK++ +K
Sbjct: 107 EELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAA 166
Query: 284 QI 285
Q+
Sbjct: 167 QL 168
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 50.1 bits (118), Expect = 2e-06
Identities = 53/245 (21%), Positives = 113/245 (46%), Gaps = 23/245 (9%)
Query: 51 IDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISEL-ENRE 109
+ E E ++ L+ V SE +++INT EK + KLQ +I L E +E
Sbjct: 1244 LKEHQETIDELRRSV-SEKTAQIINTQ------------DLEKSHTKLQEEIPVLHEEQE 1290
Query: 110 LLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLK 169
LL V E + + T + + + + + K + T + E LRL E+ ++ + +K
Sbjct: 1291 LLPNVKEVSETQETMNELELLTEQSTTK-----DSTTLARIEMERLRLNEKFQESQEEIK 1345
Query: 170 TIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLN-- 227
++ + N K LE ++ QL + ++ K Q+ + + +K + +T
Sbjct: 1346 SLTKERDNLKTIKEALE--VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIV 1403
Query: 228 DKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKD 287
+ E K + L + ++L + ++L + E++ ++ + ++E+L ++DQ+K+
Sbjct: 1404 SEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKE 1463
Query: 288 LRKRL 292
K +
Sbjct: 1464 NIKEI 1468
Score = 48.9 bits (115), Expect = 5e-06
Identities = 54/269 (20%), Positives = 120/269 (44%), Gaps = 28/269 (10%)
Query: 50 TIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRE 109
T D ++EV L+ +S+ + +L +++ ++ +K +++ +EL+N+E
Sbjct: 1118 TCDRLAEVEEKLKE------KSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKE 1171
Query: 110 LLEQVAEFEKAEIT---SSNKKPILDVTKPK--LAPLNEGGTAEL--LNKEILRLQEENE 162
L + E E+ E+ + N + + +TK + L L + E L I ++
Sbjct: 1172 LTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGL 1231
Query: 163 KLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEF 222
+ K LK I + +L +++ + N +D K+ E V + E
Sbjct: 1232 QTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQEL 1291
Query: 223 QKTLNDKTENQKSLEE--------------NLATAKHDLLRVQEQLHMAEKELEKKFQQT 268
+ + +E Q+++ E LA + + LR+ E+ +++E++ ++
Sbjct: 1292 LPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKER 1351
Query: 269 AAYRNMKEILTKKNDQIKD-LRKRLAQYE 296
+ +KE L K+DQ+K+ +R+ LA+ +
Sbjct: 1352 DNLKTIKEALEVKHDQLKEHIRETLAKIQ 1380
Score = 47.4 bits (111), Expect = 2e-05
Identities = 77/311 (24%), Positives = 126/311 (40%), Gaps = 39/311 (12%)
Query: 6 LNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDE----VSEVLNGL 61
L + N V++Y + K + LK + DL E +E D+ + E+ N
Sbjct: 503 LRADYDNLVLDYEQLRTEKEEMELKLKEK--NDLDEFEALERKTKKDQEMQLIHEISNLK 560
Query: 62 QAVVHSEV-ESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 120
V H+EV +L N + V LLR+ Q +K L+ D +LEN ++ + E
Sbjct: 561 NLVKHAEVYNQDLENELSSKVELLREKEDQIKK--LQEYIDSQKLENIKM-DLSYSLESI 617
Query: 121 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIE--IQATNA 178
E K+ + D L E L E L L+E+ ++L + K +E IQ +
Sbjct: 618 EDPKQMKQTLFDAETVALDAKRESA---FLRSENLELKEKMKELATTYKQMENDIQLYQS 674
Query: 179 -LDEKSK----LEKALQDLQLDQGNQKDFIKAQD----LSNLENTVAALKSEFQKTLNDK 229
L+ K K LEK LQ + I + L NLE + ++ QK LN +
Sbjct: 675 QLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLE--LEGKITDLQKELNKE 732
Query: 230 TENQ-------------KSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKE 276
E KSL + + ++ E+LH+ E +K F + + +
Sbjct: 733 VEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQ 792
Query: 277 ILTKKNDQIKD 287
L ++ + KD
Sbjct: 793 GLLEEIGKTKD 803
Score = 44.7 bits (104), Expect = 1e-04
Identities = 54/275 (19%), Positives = 112/275 (40%), Gaps = 25/275 (9%)
Query: 40 KESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNV--LLLRQLFAQAEKWYLK 97
+E L+ + + E E +N L+ + + A + L L + F ++++
Sbjct: 1287 EEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKS 1346
Query: 98 LQTDISELEN----------------RELLEQVAEFEKAEITSSNKKPILDVTKPKLAPL 141
L + L+ RE L ++ E + + S N K + T ++ +
Sbjct: 1347 LTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEM 1406
Query: 142 NEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKD 201
+ + +LR++ E L RL+ + + EK L++ + LQ + K+
Sbjct: 1407 EQFKPKD---SALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKE 1463
Query: 202 FIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKEL 261
IK +LE T LK L ++ E L NL+ + ++ +Q+QL +L
Sbjct: 1464 NIKEIVAKHLE-TEEELKVA-HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKL 1521
Query: 262 EKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
+ K Q+ Y ++ K+ ++++ L Q++
Sbjct: 1522 QNKIQE--IYEKEEQFNIKQISEVQEKVNELKQFK 1554
Score = 44.7 bits (104), Expect = 1e-04
Identities = 46/220 (20%), Positives = 99/220 (45%), Gaps = 19/220 (8%)
Query: 84 LRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNE 143
LR + ++ +Q D+ E N +L E++ E + E K ++ T+ K++ +
Sbjct: 1793 LRGIVSEKTDKLSNMQKDL-ENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEM-- 1849
Query: 144 GGTAELLNKEIL-------RLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQ 196
E L K+I +L+ EN L +L + + + E+ L + + L+L++
Sbjct: 1850 ----EQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLER 1905
Query: 197 GNQKDFIKAQDLSNLE-----NTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQ 251
K+ ++ +LE T L E ++T++ E ++ + DL + +
Sbjct: 1906 DQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSK 1965
Query: 252 EQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKR 291
++L +EL+KK Q + + KK ++++ L+K+
Sbjct: 1966 DELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQ 2005
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/213 (26%), Positives = 106/213 (49%), Gaps = 27/213 (12%)
Query: 91 AEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPK-LAPLNEGGTAEL 149
A+K + L+ S ++ R+ L +V E K E K L TK + L E TA +
Sbjct: 1874 AQKLHENLEEMKSVMKERDNLRRVEETLKLE--RDQLKESLQETKARDLEIQQELKTARM 1931
Query: 150 LNKEILRLQEENEKLKSRL--KTIEIQATNALDEKSK--LEKALQDLQLDQGNQKDFIKA 205
L+KE +E +KL+ ++ KTI+I +KSK L+K +Q+LQ + ++
Sbjct: 1932 LSKEH---KETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQK---KELQLLRV 1985
Query: 206 QDLSNLENTVAALKSEFQKTLNDKTENQKSLE-ENLA--TAKHDLLRVQEQLHMAEKELE 262
++ N+ + K +N+ + +K E +NL+ + + D ++ ++LH + +E+
Sbjct: 1986 KEDVNMSH----------KKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIR 2035
Query: 263 KKFQQTAAYRNMKEILTKKNDQ-IKDLRKRLAQ 294
++ R +KE L + DQ I LR+ +A+
Sbjct: 2036 IVAKERDELRRIKESLKMERDQFIATLREMIAR 2068
Score = 40.0 bits (92), Expect = 0.002
Identities = 60/275 (21%), Positives = 117/275 (42%), Gaps = 29/275 (10%)
Query: 37 QDLKESRLVEDTFTI--DEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKW 94
++ +E + V++ I D++ E + A + E E T V ++ + E
Sbjct: 1590 KEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHL 1649
Query: 95 YLKLQTDISELEN------------RELLEQVAEFEKAEITSSNKKPILDVTKPKLAP-L 141
+ +T LEN E LE++ K + + L V + +L L
Sbjct: 1650 KEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENL 1709
Query: 142 NEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKD 201
E T +L +E L++ + LK +TI+ + + EK+ + ++Q D + D
Sbjct: 1710 RETITRDLEKQEELKIVHMH--LKEHQETID-KLRGIVSEKTN---EISNMQKDLEHSND 1763
Query: 202 FIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKEL 261
+KAQDL E A L ++ E L ++ L +Q+ L + +L
Sbjct: 1764 ALKAQDLKIQEELRIA-----HMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKL 1818
Query: 262 EKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
++K Q+ A N +++T K D + + +K++++ E
Sbjct: 1819 QEKIQELKA--NEHQLITLKKD-VNETQKKVSEME 1850
Score = 36.6 bits (83), Expect = 0.028
Identities = 52/252 (20%), Positives = 105/252 (41%), Gaps = 44/252 (17%)
Query: 40 KESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQ 99
KES++++ ++ ++++ LQA VH ++ + + +L+ A K Y +
Sbjct: 2400 KESKIIKMQKELEVTNDIIAKLQAKVHE--SNKCLEKTKETIQVLQDKVALGAKPY---K 2454
Query: 100 TDISELENR------ELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKE 153
+I +L+ + E ++ EFEK EI+++ T E KE
Sbjct: 2455 EEIEDLKMKLVKIDLEKMKNAKEFEK-EISATK------------------ATVE-YQKE 2494
Query: 154 ILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQG-----NQKDFIKAQDL 208
++RL EN + ++ + Q T+ + E + + + + L G N K I +
Sbjct: 2495 VIRLLRENLR-----RSQQAQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEH 2549
Query: 209 SNLENTVAALKSEFQKTLNDKTE---NQKSLEENLATAKHDLLRVQEQLHMAEKELEKKF 265
LE ++ LK + ++ + K E N + L + T K L+ + + + K
Sbjct: 2550 IRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKREAHKQVTCENSPKSP 2609
Query: 266 QQTAAYRNMKEI 277
+ T K+I
Sbjct: 2610 KVTGTASKKKQI 2621
Score = 35.4 bits (80), Expect = 0.061
Identities = 57/251 (22%), Positives = 101/251 (40%), Gaps = 63/251 (25%)
Query: 24 KRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLL 83
K+ L K + D+K++ ++E I + + N LQ ++ S +
Sbjct: 1018 KQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI-------------- 1063
Query: 84 LRQLFAQAEKWYLKLQTDISE-----LENRELLEQVAEFEKAEITSSNKKPILDVTKPKL 138
AEK LK TD+ E +EN+E L + + KK V + K
Sbjct: 1064 -------AEKEQLK--TDLKENIEMTIENQEELRLLGD--------ELKKQQEIVAQEKN 1106
Query: 139 APLNEGGTAELLNKEILRLQEENEKLKSR---LKTIEIQATNALDEKSKLEKALQDLQLD 195
+ + G L++ RL E EKLK + L+ + Q N +E S+++K
Sbjct: 1107 HAIKKEGE---LSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQK-------- 1155
Query: 196 QGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLH 255
K ++ NL+N + + + ++ E + L EN K + + ++ L
Sbjct: 1156 --------KINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVK-SITKERKVL- 1205
Query: 256 MAEKELEKKFQ 266
KEL+K F+
Sbjct: 1206 ---KELQKSFE 1213
Score = 33.9 bits (76), Expect = 0.18
Identities = 64/301 (21%), Positives = 125/301 (41%), Gaps = 25/301 (8%)
Query: 7 NEHHQNEVINYMRFAR---SKRGLRLKTVDSCFQDLKE-SRLVEDTFT-IDEVSEVLNGL 61
NE E++N + A+ S G + Q+L+E +R V++ ++++ E L
Sbjct: 840 NERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENR 899
Query: 62 QAVVHS-EVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 120
+ + + E E LI L + Q EK LK + ++E +L + +
Sbjct: 900 DSTLQTVEREKTLITEKLQQTLEEVKTLTQ-EKDDLKQLQESLQIERDQLKSDIHDTVNM 958
Query: 121 EI-TSSNKKPILDVTKPKLAPLNEGGTAELLNKEI---LRLQEENEKLKSRLKTIEIQAT 176
I T + L+ K +N +++E+ L ++E + K + Q
Sbjct: 959 NIDTQEQLRNALESLKQHQETINT--LKSKISEEVSRNLHMEENTGETKDEFQ----QKM 1012
Query: 177 NALDEKSKLE-KALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKS 235
+D+K LE K Q L D + + + + + +L L+ + + +K + +
Sbjct: 1013 VGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTD 1072
Query: 236 LEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQY 295
L+EN+ + QE+L + EL+K+ + A +N KK ++ RLA+
Sbjct: 1073 LKENIEMT----IENQEELRLLGDELKKQQEIVAQEKNH---AIKKEGELSRTCDRLAEV 1125
Query: 296 E 296
E
Sbjct: 1126 E 1126
Score = 30.0 bits (66), Expect = 2.6
Identities = 44/204 (21%), Positives = 83/204 (40%), Gaps = 42/204 (20%)
Query: 98 LQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRL 157
+ T+I+ ++ + + E +++ + S+ + T L+ + +LLN+E
Sbjct: 442 IPTNITTKTHKLSINLLREIDESVCSESD---VFSNTLDTLSEIEWNPATKLLNQE---- 494
Query: 158 QEENEKLKSRLKTIEIQATN-ALD-EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTV 215
++S L ++ N LD E+ + EK +L+L + N DL E
Sbjct: 495 -----NIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKN--------DLDEFEALE 541
Query: 216 AALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMK 275
K + + L + N K+L ++ DL E EL K
Sbjct: 542 RKTKKDQEMQLIHEISNLKNLVKHAEVYNQDL----------ENELSSKV---------- 581
Query: 276 EILTKKNDQIKDLRKRLAQYEPED 299
E+L +K DQIK L++ + + E+
Sbjct: 582 ELLREKEDQIKKLQEYIDSQKLEN 605
Score = 29.6 bits (65), Expect = 3.4
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 7/96 (7%)
Query: 148 ELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKA-Q 206
E +NK + +E EK K L I+ + + + L+DL+L+Q + +
Sbjct: 2189 ESINKFEMDFIDEVEKQKELL----IKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILK 2244
Query: 207 DLSNLENTVAALKSEFQKTLNDKTENQKSLEENLAT 242
D S E+ ++K+EFQ+ L+++ E + LEE L T
Sbjct: 2245 DFS--ESEFPSIKTEFQQVLSNRKEMTQFLEEWLNT 2278
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/242 (23%), Positives = 110/242 (45%), Gaps = 22/242 (9%)
Query: 61 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 120
++ ++ ++ E I + LR +AEK +L+ + LE+R + E +E
Sbjct: 1243 VRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESR-ISELTSELTDE 1301
Query: 121 EITSSNKKPILDVTKPKLAPLNEGGTAELLN--KEILRLQEENEKLKSRLKTIEIQATNA 178
T + +LD TAE L KE+ LQ + + LK +++ +E++ A
Sbjct: 1302 RNTGESASQLLDAE-----------TAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEA 1350
Query: 179 -LDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLE 237
L +++ + D D G + + + ++ T L+ EF+ L + +N++ LE
Sbjct: 1351 RLIRAAEINGEVDDD--DAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLE 1408
Query: 238 ENLATAKHDLLRVQEQLHMAEKELEKKFQQ-TAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
L DL E+ A ++L+KK Q+ TA ++ K L + + +L K+ +++
Sbjct: 1409 RRLG----DLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFD 1464
Query: 297 PE 298
E
Sbjct: 1465 SE 1466
Score = 38.1 bits (87), Expect = 0.009
Identities = 48/188 (25%), Positives = 94/188 (50%), Gaps = 16/188 (8%)
Query: 92 EKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNE-GGTAELL 150
E+ +LQ + +E++NR LE+ E + E+ +K + ++ LA +N+ E
Sbjct: 1731 EEQLSRLQREKNEIQNR--LEEDQE-DMNELMKKHKAAVAQASRD-LAQINDLQAQLEEA 1786
Query: 151 NKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSN 210
NKE LQE+ + L+S+++ +E Q+ S+ E +++L+ + +F + Q +
Sbjct: 1787 NKEKQELQEKLQALQSQVEFLE-QSMVDKSLVSRQEAKIRELE----TRLEFERTQ-VKR 1840
Query: 211 LENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKEL-EKKFQQTA 269
LE+ + LK +K ++ +Q+ EN K R+Q QL ++E+ E ++
Sbjct: 1841 LESLASRLKENMEKLTEER--DQRIAAEN--REKEQNKRLQRQLRDTKEEMGELARKEAE 1896
Query: 270 AYRNMKEI 277
A R E+
Sbjct: 1897 ASRKKHEL 1904
Score = 37.7 bits (86), Expect = 0.012
Identities = 56/255 (21%), Positives = 103/255 (40%), Gaps = 61/255 (23%)
Query: 91 AEKWYLKLQTDISELENRELLEQVA--EFEKAEITSSNKKPILDVTKPK--LAPLN---- 142
AE + LK Q + +++ ++V E E +I+S K + K K L L
Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
Query: 143 --------EGGTAELLNKEILRLQEENEKLKS----------------------RLKTIE 172
+ GT ++L + LRL+ E E+++ +LK +E
Sbjct: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
Query: 173 IQATNALDEKSKLEKALQDLQ------LDQGNQKDFIKAQDLSNLENTVAALKSEFQKTL 226
+Q ++K K+ + ++L+ DQ N++DF + L AL ++ Q L
Sbjct: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
Query: 227 NDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKND--- 283
+ +N A +K ++ +++ QL E +F AA + K + + D
Sbjct: 1673 DHL--------KNSAPSKREIAQLKNQLE------ESEFTCAAAVKARKAMEVEIEDLHL 1718
Query: 284 QIKDLRKRLAQYEPE 298
QI D+ K E +
Sbjct: 1719 QIDDIAKAKTALEEQ 1733
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 50.1 bits (118), Expect = 2e-06
Identities = 56/242 (23%), Positives = 110/242 (45%), Gaps = 22/242 (9%)
Query: 61 LQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 120
++ ++ ++ E I + LR +AEK +L+ + LE+R + E +E
Sbjct: 1243 VRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESR-ISELTSELTDE 1301
Query: 121 EITSSNKKPILDVTKPKLAPLNEGGTAELLN--KEILRLQEENEKLKSRLKTIEIQATNA 178
T + +LD TAE L KE+ LQ + + LK +++ +E++ A
Sbjct: 1302 RNTGESASQLLDAE-----------TAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEA 1350
Query: 179 -LDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLE 237
L +++ + D D G + + + ++ T L+ EF+ L + +N++ LE
Sbjct: 1351 RLIRAAEINGEVDDD--DAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLE 1408
Query: 238 ENLATAKHDLLRVQEQLHMAEKELEKKFQQ-TAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
L DL E+ A ++L+KK Q+ TA ++ K L + + +L K+ +++
Sbjct: 1409 RRLG----DLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFD 1464
Query: 297 PE 298
E
Sbjct: 1465 SE 1466
Score = 38.1 bits (87), Expect = 0.009
Identities = 48/188 (25%), Positives = 94/188 (50%), Gaps = 16/188 (8%)
Query: 92 EKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNE-GGTAELL 150
E+ +LQ + +E++NR LE+ E + E+ +K + ++ LA +N+ E
Sbjct: 1731 EEQLSRLQREKNEIQNR--LEEDQE-DMNELMKKHKAAVAQASRD-LAQINDLQAQLEEA 1786
Query: 151 NKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSN 210
NKE LQE+ + L+S+++ +E Q+ S+ E +++L+ + +F + Q +
Sbjct: 1787 NKEKQELQEKLQALQSQVEFLE-QSMVDKSLVSRQEAKIRELE----TRLEFERTQ-VKR 1840
Query: 211 LENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKEL-EKKFQQTA 269
LE+ + LK +K ++ +Q+ EN K R+Q QL ++E+ E ++
Sbjct: 1841 LESLASRLKENMEKLTEER--DQRIAAEN--REKEQNKRLQRQLRDTKEEMGELARKEAE 1896
Query: 270 AYRNMKEI 277
A R E+
Sbjct: 1897 ASRKKHEL 1904
Score = 37.7 bits (86), Expect = 0.012
Identities = 56/255 (21%), Positives = 103/255 (40%), Gaps = 61/255 (23%)
Query: 91 AEKWYLKLQTDISELENRELLEQVA--EFEKAEITSSNKKPILDVTKPK--LAPLN---- 142
AE + LK Q + +++ ++V E E +I+S K + K K L L
Sbjct: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
Query: 143 --------EGGTAELLNKEILRLQEENEKLKS----------------------RLKTIE 172
+ GT ++L + LRL+ E E+++ +LK +E
Sbjct: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
Query: 173 IQATNALDEKSKLEKALQDLQ------LDQGNQKDFIKAQDLSNLENTVAALKSEFQKTL 226
+Q ++K K+ + ++L+ DQ N++DF + L AL ++ Q L
Sbjct: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
Query: 227 NDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKND--- 283
+ +N A +K ++ +++ QL E +F AA + K + + D
Sbjct: 1673 DHL--------KNSAPSKREIAQLKNQLE------ESEFTCAAAVKARKAMEVEIEDLHL 1718
Query: 284 QIKDLRKRLAQYEPE 298
QI D+ K E +
Sbjct: 1719 QIDDIAKAKTALEEQ 1733
>gi|31542661 transmembrane protein 57 [Homo sapiens]
Length = 664
Score = 50.1 bits (118), Expect = 2e-06
Identities = 66/265 (24%), Positives = 118/265 (44%), Gaps = 52/265 (19%)
Query: 38 DLKESRLVEDTFT--IDEVSEVLNGLQAVVHS-EVESELINTAYTNVLLLRQLFAQAEKW 94
DL+ SR VE I +S G+++ + E+EL+ N + ++Q
Sbjct: 396 DLQASRQVEQELRSQISSLSSTERGIRSEMGQLRQENELLQNKLHNAVQMKQ-------- 447
Query: 95 YLKLQTDISELENRELLEQVAE--FEKAEITSSNKKPILDVTKPK---LAPLNEGGTAEL 149
K + +IS+LE + EQ A EK + +K + + T + A + G E
Sbjct: 448 --KDKQNISQLEKKLKAEQEARSFVEKQLMEEKKRKKLEEATAARAVAFAAASRGECTET 505
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLS 209
L I L+ E +KL +K E D+ +LE +Q+L+ + N+KD
Sbjct: 506 LRNRIRELEAEGKKLTMDMKVKE-------DQIRELELKVQELRKYKENEKD-------- 550
Query: 210 NLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTA 269
E ++AL + + DKT++ LE +L+ L + L A+++LE Q
Sbjct: 551 -TEVLMSALSA-----MQDKTQH---LENSLSAETRIKLDLFSALGDAKRQLEIAQGQ-- 599
Query: 270 AYRNMKEILTKKNDQIKDLRKRLAQ 294
+ +K+ +IKDL++++A+
Sbjct: 600 --------ILQKDQEIKDLKQKIAE 616
>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
sapiens]
Length = 693
Score = 50.1 bits (118), Expect = 2e-06
Identities = 60/263 (22%), Positives = 117/263 (44%), Gaps = 25/263 (9%)
Query: 34 SCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEK 93
SC + + RL + TI E + + + V S + +L Y + + Q
Sbjct: 191 SCREAVLHRRLQQ---TIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERM 247
Query: 94 WYLKLQTDISELENRELLEQVAEFEKA--EITSSNKKPILDVTKPKLAPLNEGGTAELLN 151
W + ++ + E + + ++ E E++ E+ + KP P LAP E L
Sbjct: 248 WKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKP------PSLAPPAVTSVVEQLQ 301
Query: 152 KEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL 211
E L++E E L+ +L++ +++ AL SK +K Q LQ Q++ ++ Q++ +
Sbjct: 302 DEAKHLRQEVEGLEGKLQS-QVENNQALSLLSKEQK--QRLQ----EQEEMLREQEVQRV 354
Query: 212 ENTVAALKSEFQKTLNDKT-ENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAA 270
+ N++ E QK+L+E + R+++Q KE E+ +Q
Sbjct: 355 REQERLCEQ------NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 271 YRNMKEILTKKNDQIKDLRKRLA 293
+ +E L KK ++++ +RLA
Sbjct: 409 LWDQEERLWKKEERLQKQEERLA 431
Score = 37.0 bits (84), Expect = 0.021
Identities = 28/107 (26%), Positives = 51/107 (47%)
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLS 209
L K+ RL++E E+L+ + K + Q ++ +L+K + L L Q ++ D A+
Sbjct: 388 LRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQC 447
Query: 210 NLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHM 256
+ E+ KS Q K +K EE+L A +++ QL +
Sbjct: 448 SFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQLSL 494
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 49.7 bits (117), Expect = 3e-06
Identities = 66/296 (22%), Positives = 134/296 (45%), Gaps = 41/296 (13%)
Query: 8 EHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHS 67
E HQ E+ + +L + K S E I+E+ + LQ ++ +
Sbjct: 694 EQHQTEIRDLQD--------QLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIA 745
Query: 68 EVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQV-AEFE--KAEITS 124
+ E E ++L R+ A K LK + + E +L EQ AE + + +
Sbjct: 746 KEEQE-------DLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEE 798
Query: 125 SNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSK 184
+ K + ++ + ++ GT + LQEENEKL+ R + +E + ++
Sbjct: 799 ATKNVEVLASRSNTSEQDQAGT----EMRVKLLQEENEKLQGRSEELERRV-------AQ 847
Query: 185 LEKALQDLQLDQGNQKDFIKAQ--DLSNLENTVAALKSEFQKTLNDKTENQKSLEENLAT 242
L++ ++DL+ D+ K+ +K ++ LE + + E ++ ++ + ++LE L
Sbjct: 848 LQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALVHARKEEKEAVSAR----RALENELEA 903
Query: 243 AKHDLLR-VQEQLHMAEKELEKKFQQTAAYRNMKEILTKK----NDQIKDLRKRLA 293
A+ +L + QEQ ++EK L+++ +Q R +K + + I+ L+K +A
Sbjct: 904 AQGNLSQTTQEQKQLSEK-LKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMA 958
Score = 44.7 bits (104), Expect = 1e-04
Identities = 51/222 (22%), Positives = 95/222 (42%), Gaps = 43/222 (19%)
Query: 92 EKWYL-----KLQTDISEL------ENRELLEQVAEF------EKAEITSSNKKPILDVT 134
E+W+L KLQ +++++ EL Q+ E+ E AE+ K+ L+
Sbjct: 942 ERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLEAE 1001
Query: 135 KPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQL 194
K +L + ++Q+E ++ L+ + AL ++ LE+ L+DL+
Sbjct: 1002 KSRLTAM--------------KMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEY 1047
Query: 195 DQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQL 254
+ K +K D S L + S+ + L ++ N L E ++ R +EQ+
Sbjct: 1048 EL-EAKSHLK-DDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERIS-------RSREQM 1098
Query: 255 HMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYE 296
EL Q+ AA ++++ Q KDL+ R+ E
Sbjct: 1099 EQLRNEL---LQERAARQDLECDKISLERQNKDLKSRIIHLE 1137
Score = 40.4 bits (93), Expect = 0.002
Identities = 46/201 (22%), Positives = 92/201 (45%), Gaps = 15/201 (7%)
Query: 90 QAEKWYLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAEL 149
QA LK Q ++++ N E +Q+ E ++ N D TK K+ + E L
Sbjct: 534 QATPDLLKGQQELTQQTNEETAKQILYNYLKEGSTDND----DATKRKVNLVFEK-IQTL 588
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLS 209
++ Q N+ S T E++ + L++KSKL + +LQ Q + Q++
Sbjct: 589 KSRAAGSAQGNNQACNS---TSEVK--DLLEQKSKLTIEVAELQRQL--QLEVKNQQNIK 641
Query: 210 NLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTA 269
+ A E + N+K E +L++ L ++ +L + E+L + E E Q
Sbjct: 642 EERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMERE---QHQT 698
Query: 270 AYRNMKEILTKKNDQIKDLRK 290
R++++ L++ +D++ ++
Sbjct: 699 EIRDLQDQLSEMHDELDSAKR 719
Score = 38.5 bits (88), Expect = 0.007
Identities = 34/171 (19%), Positives = 79/171 (46%), Gaps = 13/171 (7%)
Query: 137 KLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLD- 195
++A L E+ N++ ++EE E++++ L+ + Q ++E S L++ L++ + +
Sbjct: 622 EVAELQRQLQLEVKNQQ--NIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGEL 679
Query: 196 QGNQKDFIKAQ--------DLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDL 247
+ N ++ + + ++ +L++ ++ + E + + +L E L AK DL
Sbjct: 680 RKNLEELFQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDL 739
Query: 248 LRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQYEPE 298
+ E L K+ ++ A + + +DQ D K QY+ E
Sbjct: 740 QDLLIAKEEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKE--QYDAE 788
Score = 34.3 bits (77), Expect = 0.14
Identities = 49/241 (20%), Positives = 106/241 (43%), Gaps = 37/241 (15%)
Query: 3 ELGLNEHHQNEVINYMRFARSKRGLRLKTVDSCFQDLKESRLVEDTFTIDEVSEVLNGLQ 62
E+ L E N + R +RS+ + ++ +L + R D++S
Sbjct: 1074 EMELEEERNNSDLLSERISRSR-----EQMEQLRNELLQERAARQDLECDKISLERQ--- 1125
Query: 63 AVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKAEI 122
+ +++S +I+ L + E ++++ I+ELE+R E E ++A +
Sbjct: 1126 ---NKDLKSRIIH-------LEGSYRSSKEGLVVQMEARIAELEDRLESE---ERDRANL 1172
Query: 123 TSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALDEK 182
SN++ V + + ++ E L L ++ ++L RLK ++ Q A +E
Sbjct: 1173 QLSNRRLERKVKELVMQ----------VDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEI 1222
Query: 183 SKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQ-KTLNDKTENQKSLEENLA 241
+LE + + LQ + Q D + +L+ + ++K + + K L K + +++L+
Sbjct: 1223 DRLESSKKKLQRELEEQMDMNE-----HLQGQLNSMKKDLRLKKLPSKVLDDMDDDDDLS 1277
Query: 242 T 242
T
Sbjct: 1278 T 1278
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 48.9 bits (115), Expect = 5e-06
Identities = 51/219 (23%), Positives = 105/219 (47%), Gaps = 25/219 (11%)
Query: 99 QTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQ 158
+T++ + + ++ E K+ + SS + D++K + E +A +L L +
Sbjct: 545 RTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSR-----ENLSAVMLYNPGLEFE 599
Query: 159 ----EENEKLKSRLKTIEIQATNALDEKSKLEKALQD----------LQLDQGNQKDFIK 204
EE EKL+S+ K IE +K++LE+ Q+ +QL Q++ +K
Sbjct: 600 RQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLK 659
Query: 205 AQDLSNLENTVAALKSEFQKTLNDKTENQKSLE-ENLATAKHDLLRVQEQL-HMAEKELE 262
+ ++EN + L +E +K ++ Q+ +E + + LRVQE+L + E
Sbjct: 660 RRSF-HIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNN 718
Query: 263 KKFQQTAAYRNMKEILTKKNDQIKDL---RKRLAQYEPE 298
+K ++ ++ + ++ +K++Q L +KRL + E E
Sbjct: 719 EKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKE 757
Score = 29.3 bits (64), Expect = 4.4
Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 13/128 (10%)
Query: 152 KEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL 211
+++ + Q +L+ T E A A E+ +K + L+ + Q++ ++ + L+ L
Sbjct: 954 EQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALE-RALARL 1012
Query: 212 ENTVAALK----------SEFQK--TLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEK 259
E +AL+ + QK +LN + Q L+ +L + L + QE+L +
Sbjct: 1013 ERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYEIQ 1072
Query: 260 ELEKKFQQ 267
+L++K +
Sbjct: 1073 QLKQKIYE 1080
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 48.5 bits (114), Expect = 7e-06
Identities = 59/263 (22%), Positives = 117/263 (44%), Gaps = 25/263 (9%)
Query: 34 SCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEK 93
SC + + + RL + TI E + + + V S + +L Y + + Q
Sbjct: 191 SCREAVLQRRLQQ---TIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERM 247
Query: 94 WYLKLQTDISELENRELLEQVAEFEKA--EITSSNKKPILDVTKPKLAPLNEGGTAELLN 151
W + ++ + E + + ++ E E++ E+ + +P P LAP E L
Sbjct: 248 WKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEP------PSLAPPAVTSVVEQLQ 301
Query: 152 KEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL 211
E L++E E L+ +L++ +++ AL SK +K Q LQ Q++ ++ Q+ +
Sbjct: 302 DEAKHLRQEVEGLEGKLQS-QVENNQALSLLSKEQK--QRLQ----EQEEMLREQEAQRV 354
Query: 212 ENTVAALKSEFQKTLNDKT-ENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAA 270
+ N++ E QK+L+E + R+++Q KE E+ +Q
Sbjct: 355 REQERLCEQ------NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 271 YRNMKEILTKKNDQIKDLRKRLA 293
+ +E L KK ++++ +RLA
Sbjct: 409 LWDQEERLWKKEERLQKQEERLA 431
Score = 36.2 bits (82), Expect = 0.036
Identities = 28/107 (26%), Positives = 51/107 (47%)
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLS 209
L K+ RL++E E+L+ + K + Q ++ +L+K + L L Q ++ D A+
Sbjct: 388 LRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQC 447
Query: 210 NLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHM 256
+ E+ KS Q K +K EE+L A +++ QL +
Sbjct: 448 SFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSL 494
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 48.5 bits (114), Expect = 7e-06
Identities = 59/263 (22%), Positives = 117/263 (44%), Gaps = 25/263 (9%)
Query: 34 SCFQDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEK 93
SC + + + RL + TI E + + + V S + +L Y + + Q
Sbjct: 191 SCREAVLQRRLQQ---TIKERALLNAHVTQVTESLKQVQLERDEYAKHIKGERARWQERM 247
Query: 94 WYLKLQTDISELENRELLEQVAEFEKA--EITSSNKKPILDVTKPKLAPLNEGGTAELLN 151
W + ++ + E + + ++ E E++ E+ + +P P LAP E L
Sbjct: 248 WKMSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEP------PSLAPPAVTSVVEQLQ 301
Query: 152 KEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNL 211
E L++E E L+ +L++ +++ AL SK +K Q LQ Q++ ++ Q+ +
Sbjct: 302 DEAKHLRQEVEGLEGKLQS-QVENNQALSLLSKEQK--QRLQ----EQEEMLREQEAQRV 354
Query: 212 ENTVAALKSEFQKTLNDKT-ENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAA 270
+ N++ E QK+L+E + R+++Q KE E+ +Q
Sbjct: 355 REQERLCEQ------NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKR 408
Query: 271 YRNMKEILTKKNDQIKDLRKRLA 293
+ +E L KK ++++ +RLA
Sbjct: 409 LWDQEERLWKKEERLQKQEERLA 431
Score = 36.2 bits (82), Expect = 0.036
Identities = 28/107 (26%), Positives = 51/107 (47%)
Query: 150 LNKEILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLS 209
L K+ RL++E E+L+ + K + Q ++ +L+K + L L Q ++ D A+
Sbjct: 388 LRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQC 447
Query: 210 NLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHM 256
+ E+ KS Q K +K EE+L A +++ QL +
Sbjct: 448 SFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSL 494
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 48.1 bits (113), Expect = 9e-06
Identities = 59/236 (25%), Positives = 105/236 (44%), Gaps = 35/236 (14%)
Query: 66 HSEVESELINTAYTNVLL-------LRQLFAQAEKWYLKLQTDISELENRELLEQVAEFE 118
H E E+EL+ TN+ + L Q ++ E+ KL+ + +N + E E
Sbjct: 636 HLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Query: 119 KAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNA 178
+++ N + +V K A + +L NKE L+ E E+LK L+ ++ +
Sbjct: 696 NSQLDEENLELRRNVESLKCASMKMA-QLQLENKE---LESEKEQLKKGLELLKA----S 747
Query: 179 LDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEE 238
+ +LE + Q L ++ NQ+ + L N + L+SE Q + ENQ +L++
Sbjct: 748 FKKTERLEVSYQGLDIE--NQR---LQKTLENSNKKIQQLESELQDL---EMENQ-TLQK 798
Query: 239 NLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQ 294
NL E+L ++ K LE+ ++ + L K Q++ KRL Q
Sbjct: 799 NL-----------EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Score = 46.6 bits (109), Expect = 3e-05
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 19/191 (9%)
Query: 104 ELENRELLEQVAEFEKA-EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENE 162
E+EN+ L + V E + N IL + K + L+K++ L+ E
Sbjct: 466 EMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN----------QRLSKKVEILENEIV 515
Query: 163 KLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEF 222
+ K L+ + + + + EK++LEK ++ L+ + Q ++ Q+ +L TV++L+
Sbjct: 516 QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE-QENEHLNQTVSSLRQRS 574
Query: 223 Q----KTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELE---KKFQQTAAYRNMK 275
Q + D + K L E++ L +++ + +KELE +K ++ N
Sbjct: 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL 634
Query: 276 EILTKKNDQIK 286
L K+N+ ++
Sbjct: 635 HHLEKENELLQ 645
Score = 44.3 bits (103), Expect = 1e-04
Identities = 64/310 (20%), Positives = 131/310 (42%), Gaps = 44/310 (14%)
Query: 11 QNEVINYMRFARSKR-------GLRLKTVDSCFQDLKESRLVEDTFTID----------E 53
Q E +N + ARS R LR K V + + SR E I+ E
Sbjct: 292 QQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKE 351
Query: 54 VSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQ 113
++VL + ++ ++E + + L L +A+ ++++ D+ + EL+E+
Sbjct: 352 DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Query: 114 VAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTA----------ELLNKEILRLQEENEK 163
E A+ S ++ L +++ +E A EL + +L+L+ EN+
Sbjct: 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Query: 164 LKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQ 223
L ++ + + SK+ L++++ NQ+ ++ + LEN + K Q
Sbjct: 472 LTKTVEELRTTVDSVEGNASKI------LKMEKENQR---LSKKVEILENEIVQEKQSLQ 522
Query: 224 KTLN---DKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTK 280
N D + + LE+ + T + + + Q+ + E+E E Q ++ R +I +
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLREN---SERQIKILEQENEHLNQTVSSLRQRSQISAE 579
Query: 281 KNDQIKDLRK 290
++KD+ K
Sbjct: 580 A--RVKDIEK 587
Score = 44.3 bits (103), Expect = 1e-04
Identities = 68/292 (23%), Positives = 115/292 (39%), Gaps = 59/292 (20%)
Query: 8 EHHQNEVINYMRFARSKRGLRLKTVDSCFQDLK----ESRLVEDTFTID-EVSEVLNGLQ 62
E E NY + R + LKTV ++ LK E R+V+ + I E ++ Q
Sbjct: 980 EARLEESTNYNQQLRQE----LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQ 1035
Query: 63 AVVHS--EVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 120
+V+ LI N L QAEK LK Q E +N L Q+ ++
Sbjct: 1036 ETTRELLKVKDRLIEVERNNATL------QAEKQALKTQLKQLETQNNNLQAQILALQRQ 1089
Query: 121 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 180
++ + L KL Q EN L S Q+T+ ++
Sbjct: 1090 TVSLQEQNTTLQTQNAKL-------------------QVENSTLNS-------QSTSLMN 1123
Query: 181 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 240
+ ++L +Q L+ N+ + +DL +L +++ + + L E Q S E+L
Sbjct: 1124 QNAQL--LIQQSSLENENESVIKEREDLKSLYDSLI----KDHEKLELLHERQASEYESL 1177
Query: 241 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRL 292
+ L + L + ++LE ++ Q L K+ Q++DL K L
Sbjct: 1178 ISKHGTLKSAHKNLEVEHRDLEDRYNQ----------LLKQKGQLEDLEKML 1219
Score = 42.4 bits (98), Expect = 5e-04
Identities = 52/211 (24%), Positives = 96/211 (45%), Gaps = 32/211 (15%)
Query: 97 KLQTDISELEN-RELLEQVAEFEKAEITSSNKKPI----LDVTKPKLAPLNEGGTAEL-- 149
+LQ + ELE+ +E L++ E KA + + + LD+ +L E ++
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 150 LNKEILRLQEENEKLKS----------RLKTIEIQATNALDEKSKLEKALQDLQLDQGNQ 199
L E+ L+ EN+ L+ RL+ +E + + E S+LEK + L+ +
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 200 KDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEK 259
+ + +D + EN V K N + EN K+L + + K +R++E L K
Sbjct: 842 RQQAEIKDTTLEENNV--------KIGNLEKEN-KTLSKEIGIYKESCVRLKE-LEKENK 891
Query: 260 ELEKKFQQTAAYRNMKEILTKKNDQIKDLRK 290
EL K+ A ++K ++T + D + + K
Sbjct: 892 ELVKR-----ATIDIKTLVTLREDLVSEKLK 917
Score = 40.4 bits (93), Expect = 0.002
Identities = 60/242 (24%), Positives = 108/242 (44%), Gaps = 26/242 (10%)
Query: 37 QDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESE--LINTAYTNVLLLRQLFAQAEKW 94
+DLK L + E E+L+ QA + + S+ + +A+ N+ + +
Sbjct: 1147 EDLKS--LYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQ 1204
Query: 95 YLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNE--GGTAELLNK 152
LK + + +LE +EQ EK + + N + + K KL N+ T L K
Sbjct: 1205 LLKQKGQLEDLEKMLKVEQ----EKMLLENKNHETVAAEYK-KLCGENDRLNHTYSQLLK 1259
Query: 153 EILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQG--NQKDFIKAQDLSN 210
E LQ +++ LKS L +++ T E SKL++ Q L + N + + +Q N
Sbjct: 1260 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1319
Query: 211 LENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQE--------QLHMAEKELE 262
LE L + Q + +N+ LE+N+ + DL V++ +L +++LE
Sbjct: 1320 LEEENRHLLDQIQTLM---LQNRTLLEQNMES--KDLFHVEQRQYIDKLNELRRQKEKLE 1374
Query: 263 KK 264
+K
Sbjct: 1375 EK 1376
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 48.1 bits (113), Expect = 9e-06
Identities = 59/236 (25%), Positives = 105/236 (44%), Gaps = 35/236 (14%)
Query: 66 HSEVESELINTAYTNVLL-------LRQLFAQAEKWYLKLQTDISELENRELLEQVAEFE 118
H E E+EL+ TN+ + L Q ++ E+ KL+ + +N + E E
Sbjct: 636 HLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKE 695
Query: 119 KAEITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNA 178
+++ N + +V K A + +L NKE L+ E E+LK L+ ++ +
Sbjct: 696 NSQLDEENLELRRNVESLKCASMKMA-QLQLENKE---LESEKEQLKKGLELLKA----S 747
Query: 179 LDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEE 238
+ +LE + Q L ++ NQ+ + L N + L+SE Q + ENQ +L++
Sbjct: 748 FKKTERLEVSYQGLDIE--NQR---LQKTLENSNKKIQQLESELQDL---EMENQ-TLQK 798
Query: 239 NLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRLAQ 294
NL E+L ++ K LE+ ++ + L K Q++ KRL Q
Sbjct: 799 NL-----------EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQ 843
Score = 46.6 bits (109), Expect = 3e-05
Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 19/191 (9%)
Query: 104 ELENRELLEQVAEFEKA-EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENE 162
E+EN+ L + V E + N IL + K + L+K++ L+ E
Sbjct: 466 EMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN----------QRLSKKVEILENEIV 515
Query: 163 KLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEF 222
+ K L+ + + + + EK++LEK ++ L+ + Q ++ Q+ +L TV++L+
Sbjct: 516 QEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILE-QENEHLNQTVSSLRQRS 574
Query: 223 Q----KTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEKELE---KKFQQTAAYRNMK 275
Q + D + K L E++ L +++ + +KELE +K ++ N
Sbjct: 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL 634
Query: 276 EILTKKNDQIK 286
L K+N+ ++
Sbjct: 635 HHLEKENELLQ 645
Score = 44.3 bits (103), Expect = 1e-04
Identities = 64/310 (20%), Positives = 131/310 (42%), Gaps = 44/310 (14%)
Query: 11 QNEVINYMRFARSKR-------GLRLKTVDSCFQDLKESRLVEDTFTID----------E 53
Q E +N + ARS R LR K V + + SR E I+ E
Sbjct: 292 QQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKE 351
Query: 54 VSEVLNGLQAVVHSEVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQ 113
++VL + ++ ++E + + L L +A+ ++++ D+ + EL+E+
Sbjct: 352 DNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE 411
Query: 114 VAEFEKAEITSSNKKPILDVTKPKLAPLNEGGTA----------ELLNKEILRLQEENEK 163
E A+ S ++ L +++ +E A EL + +L+L+ EN+
Sbjct: 412 NMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQS 471
Query: 164 LKSRLKTIEIQATNALDEKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQ 223
L ++ + + SK+ L++++ NQ+ ++ + LEN + K Q
Sbjct: 472 LTKTVEELRTTVDSVEGNASKI------LKMEKENQR---LSKKVEILENEIVQEKQSLQ 522
Query: 224 KTLN---DKTENQKSLEENLATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTK 280
N D + + LE+ + T + + + Q+ + E+E E Q ++ R +I +
Sbjct: 523 NCQNLSKDLMKEKAQLEKTIETLREN---SERQIKILEQENEHLNQTVSSLRQRSQISAE 579
Query: 281 KNDQIKDLRK 290
++KD+ K
Sbjct: 580 A--RVKDIEK 587
Score = 44.3 bits (103), Expect = 1e-04
Identities = 68/292 (23%), Positives = 115/292 (39%), Gaps = 59/292 (20%)
Query: 8 EHHQNEVINYMRFARSKRGLRLKTVDSCFQDLK----ESRLVEDTFTID-EVSEVLNGLQ 62
E E NY + R + LKTV ++ LK E R+V+ + I E ++ Q
Sbjct: 979 EARLEESTNYNQQLRQE----LKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQ 1034
Query: 63 AVVHS--EVESELINTAYTNVLLLRQLFAQAEKWYLKLQTDISELENRELLEQVAEFEKA 120
+V+ LI N L QAEK LK Q E +N L Q+ ++
Sbjct: 1035 ETTRELLKVKDRLIEVERNNATL------QAEKQALKTQLKQLETQNNNLQAQILALQRQ 1088
Query: 121 EITSSNKKPILDVTKPKLAPLNEGGTAELLNKEILRLQEENEKLKSRLKTIEIQATNALD 180
++ + L KL Q EN L S Q+T+ ++
Sbjct: 1089 TVSLQEQNTTLQTQNAKL-------------------QVENSTLNS-------QSTSLMN 1122
Query: 181 EKSKLEKALQDLQLDQGNQKDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENL 240
+ ++L +Q L+ N+ + +DL +L +++ + + L E Q S E+L
Sbjct: 1123 QNAQL--LIQQSSLENENESVIKEREDLKSLYDSLI----KDHEKLELLHERQASEYESL 1176
Query: 241 ATAKHDLLRVQEQLHMAEKELEKKFQQTAAYRNMKEILTKKNDQIKDLRKRL 292
+ L + L + ++LE ++ Q L K+ Q++DL K L
Sbjct: 1177 ISKHGTLKSAHKNLEVEHRDLEDRYNQ----------LLKQKGQLEDLEKML 1218
Score = 42.4 bits (98), Expect = 5e-04
Identities = 52/211 (24%), Positives = 96/211 (45%), Gaps = 32/211 (15%)
Query: 97 KLQTDISELEN-RELLEQVAEFEKAEITSSNKKPI----LDVTKPKLAPLNEGGTAEL-- 149
+LQ + ELE+ +E L++ E KA + + + LD+ +L E ++
Sbjct: 722 QLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQ 781
Query: 150 LNKEILRLQEENEKLKS----------RLKTIEIQATNALDEKSKLEKALQDLQLDQGNQ 199
L E+ L+ EN+ L+ RL+ +E + + E S+LEK + L+ +
Sbjct: 782 LESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL 841
Query: 200 KDFIKAQDLSNLENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQEQLHMAEK 259
+ + +D + EN V K N + EN K+L + + K +R++E L K
Sbjct: 842 RQQAEIKDTTLEENNV--------KIGNLEKEN-KTLSKEIGIYKESCVRLKE-LEKENK 891
Query: 260 ELEKKFQQTAAYRNMKEILTKKNDQIKDLRK 290
EL K+ A ++K ++T + D + + K
Sbjct: 892 ELVKR-----ATIDIKTLVTLREDLVSEKLK 917
Score = 40.4 bits (93), Expect = 0.002
Identities = 60/242 (24%), Positives = 108/242 (44%), Gaps = 26/242 (10%)
Query: 37 QDLKESRLVEDTFTIDEVSEVLNGLQAVVHSEVESE--LINTAYTNVLLLRQLFAQAEKW 94
+DLK L + E E+L+ QA + + S+ + +A+ N+ + +
Sbjct: 1146 EDLKS--LYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQ 1203
Query: 95 YLKLQTDISELENRELLEQVAEFEKAEITSSNKKPILDVTKPKLAPLNE--GGTAELLNK 152
LK + + +LE +EQ EK + + N + + K KL N+ T L K
Sbjct: 1204 LLKQKGQLEDLEKMLKVEQ----EKMLLENKNHETVAAEYK-KLCGENDRLNHTYSQLLK 1258
Query: 153 EILRLQEENEKLKSRLKTIEIQATNALDEKSKLEKALQDLQLDQG--NQKDFIKAQDLSN 210
E LQ +++ LKS L +++ T E SKL++ Q L + N + + +Q N
Sbjct: 1259 ETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGN 1318
Query: 211 LENTVAALKSEFQKTLNDKTENQKSLEENLATAKHDLLRVQE--------QLHMAEKELE 262
LE L + Q + +N+ LE+N+ + DL V++ +L +++LE
Sbjct: 1319 LEEENRHLLDQIQTLM---LQNRTLLEQNMES--KDLFHVEQRQYIDKLNELRRQKEKLE 1373
Query: 263 KK 264
+K
Sbjct: 1374 EK 1375
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.328
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,989,224
Number of Sequences: 37866
Number of extensions: 360680
Number of successful extensions: 4062
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 139
Number of HSP's successfully gapped in prelim test: 693
Number of HSP's that attempted gapping in prelim test: 2415
Number of HSP's gapped (non-prelim): 1927
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.