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Search of human proteins with 9955927
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9955927 acrosomal vesicle protein 1 isoform b precursor
[Homo sapiens]
(246 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9955927 acrosomal vesicle protein 1 isoform b precursor [Homo... 509 e-145
gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo... 498 e-141
gi|9955929 acrosomal vesicle protein 1 isoform c precursor [Homo... 340 7e-94
gi|9955933 acrosomal vesicle protein 1 isoform e precursor [Homo... 301 3e-82
gi|9955931 acrosomal vesicle protein 1 isoform d precursor [Homo... 290 1e-78
gi|9955937 acrosomal vesicle protein 1 isoform f precursor [Homo... 248 3e-66
gi|9955941 acrosomal vesicle protein 1 isoform h precursor [Homo... 203 1e-52
gi|9955935 acrosomal vesicle protein 1 isoform j precursor [Homo... 184 5e-47
gi|9955945 acrosomal vesicle protein 1 isoform k precursor [Homo... 94 1e-19
gi|222136622 prostate and testis expressed 3 [Homo sapiens] 55 7e-08
gi|221554530 prostate and testis expressed 4 [Homo sapiens] 50 1e-06
gi|38261962 activating transcription factor 7 interacting protei... 50 1e-06
gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens] 50 2e-06
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 43 2e-04
gi|62122917 filaggrin family member 2 [Homo sapiens] 42 4e-04
gi|57864582 hornerin [Homo sapiens] 42 5e-04
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 42 5e-04
gi|19923082 expressed in prostate and testis [Homo sapiens] 40 0.001
gi|60097902 filaggrin [Homo sapiens] 40 0.002
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 40 0.002
gi|239746922 PREDICTED: similar to cancer/testis antigen family ... 40 0.002
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 40 0.002
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 40 0.002
gi|49087132 sal-like 2 [Homo sapiens] 40 0.002
gi|33286446 opioid growth factor receptor [Homo sapiens] 40 0.002
gi|30794264 glycosylphosphatidylinositol anchored high density l... 40 0.002
gi|126090892 aggrecan isoform 2 precursor [Homo sapiens] 39 0.004
gi|126090883 aggrecan isoform 1 precursor [Homo sapiens] 39 0.004
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 38 0.007
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 38 0.007
>gi|9955927 acrosomal vesicle protein 1 isoform b precursor [Homo
sapiens]
Length = 246
Score = 509 bits (1312), Expect = e-145
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS
Sbjct: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQ 180
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQ
Sbjct: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQ 180
Query: 181 GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ 240
GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ
Sbjct: 181 GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ 240
Query: 241 SFCNKI 246
SFCNKI
Sbjct: 241 SFCNKI 246
>gi|4501879 acrosomal vesicle protein 1 isoform a precursor [Homo
sapiens]
Length = 265
Score = 498 bits (1282), Expect = e-141
Identities = 246/265 (92%), Positives = 246/265 (92%), Gaps = 19/265 (7%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS
Sbjct: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS--------------- 165
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS
Sbjct: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 180
Query: 166 ----GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 221
GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP
Sbjct: 181 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 240
Query: 222 SMNLFSHGTRMQIICCRNQSFCNKI 246
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 241 SMNLFSHGTRMQIICCRNQSFCNKI 265
>gi|9955929 acrosomal vesicle protein 1 isoform c precursor [Homo
sapiens]
Length = 210
Score = 340 bits (872), Expect = 7e-94
Identities = 182/265 (68%), Positives = 185/265 (69%), Gaps = 74/265 (27%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARGTSSQPNELS
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELS--------------------------------- 27
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
GS +H +S + GEPAATEHAEGEHTVGEQPSGEQPS
Sbjct: 28 --------GSIDHQTSV--------------QQLPGEPAATEHAEGEHTVGEQPSGEQPS 65
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG-------------- 166
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG
Sbjct: 66 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 125
Query: 167 -----TILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 221
TILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP
Sbjct: 126 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 185
Query: 222 SMNLFSHGTRMQIICCRNQSFCNKI 246
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 186 SMNLFSHGTRMQIICCRNQSFCNKI 210
>gi|9955933 acrosomal vesicle protein 1 isoform e precursor [Homo
sapiens]
Length = 176
Score = 301 bits (771), Expect = 3e-82
Identities = 164/246 (66%), Positives = 167/246 (67%), Gaps = 70/246 (28%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARG TSS
Sbjct: 1 MNRFLLLMSLYLLGSARG---------------------------------------TSS 21
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
N LS GS +H +S + GEQPSGEQPS
Sbjct: 22 QPNELS--GSIDHQTSVQQLP-----------------------------GEQPSGEQPS 50
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQ 180
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQ
Sbjct: 51 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQ 110
Query: 181 GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ 240
GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ
Sbjct: 111 GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ 170
Query: 241 SFCNKI 246
SFCNKI
Sbjct: 171 SFCNKI 176
>gi|9955931 acrosomal vesicle protein 1 isoform d precursor [Homo
sapiens]
Length = 195
Score = 290 bits (741), Expect = 1e-78
Identities = 164/265 (61%), Positives = 167/265 (63%), Gaps = 89/265 (33%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARG TSS
Sbjct: 1 MNRFLLLMSLYLLGSARG---------------------------------------TSS 21
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
N LS GS +H +S + GEQPSGEQPS
Sbjct: 22 QPNELS--GSIDHQTSVQQLP-----------------------------GEQPSGEQPS 50
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG-------------- 166
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG
Sbjct: 51 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGEHASGEQASGAPIS 110
Query: 167 -----TILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 221
TILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP
Sbjct: 111 STSTGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCP 170
Query: 222 SMNLFSHGTRMQIICCRNQSFCNKI 246
SMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 171 SMNLFSHGTRMQIICCRNQSFCNKI 195
>gi|9955937 acrosomal vesicle protein 1 isoform f precursor [Homo
sapiens]
Length = 170
Score = 248 bits (633), Expect = 3e-66
Identities = 145/246 (58%), Positives = 149/246 (60%), Gaps = 76/246 (30%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARG TSS
Sbjct: 1 MNRFLLLMSLYLLGSARG---------------------------------------TSS 21
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
N LS GS +H +S + GEQPS EQPS
Sbjct: 22 QPNELS--GSIDHQTSVQQLP-----------------------------GEQPSDEQPS 50
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQ 180
GEH SGEQP SGEQ S EQPSGEH SGEQ SG S +GTILNCYTCAYMNDQ
Sbjct: 51 GEHGSGEQP-----SGEQASGEQPSGEHASGEQASGAPISSTS-TGTILNCYTCAYMNDQ 104
Query: 181 GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ 240
GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ
Sbjct: 105 GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ 164
Query: 241 SFCNKI 246
SFCNKI
Sbjct: 165 SFCNKI 170
>gi|9955941 acrosomal vesicle protein 1 isoform h precursor [Homo
sapiens]
Length = 155
Score = 203 bits (517), Expect = 1e-52
Identities = 128/246 (52%), Positives = 134/246 (54%), Gaps = 91/246 (36%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS 60
MNRFLLLMSLYLLGSARG TSS
Sbjct: 1 MNRFLLLMSLYLLGSARG---------------------------------------TSS 21
Query: 61 GLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPS 120
N LS GS +H +S + GEQPSGEQPS
Sbjct: 22 QPNELS--GSIDHQTSVQQLP-----------------------------GEQPSGEQPS 50
Query: 121 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQ 180
GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG +
Sbjct: 51 GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG------------EH 98
Query: 181 GKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ 240
+ G I+ S GGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ
Sbjct: 99 ASGEQASGAPISSTS---------TGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQ 149
Query: 241 SFCNKI 246
SFCNKI
Sbjct: 150 SFCNKI 155
>gi|9955935 acrosomal vesicle protein 1 isoform j precursor [Homo
sapiens]
Length = 121
Score = 184 bits (468), Expect = 5e-47
Identities = 87/104 (83%), Positives = 90/104 (86%), Gaps = 6/104 (5%)
Query: 149 GSGEQPS------GEQASGEQPSGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKK 202
G+ QP+ Q S +Q GTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKK
Sbjct: 18 GTSSQPNELSGSIDHQTSVQQLPGTILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKK 77
Query: 203 IFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 246
IFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 78 IFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 121
Score = 83.2 bits (204), Expect = 2e-16
Identities = 41/41 (100%), Positives = 41/41 (100%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG 41
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG 41
>gi|9955945 acrosomal vesicle protein 1 isoform k precursor [Homo
sapiens]
Length = 81
Score = 94.0 bits (232), Expect = 1e-19
Identities = 41/41 (100%), Positives = 41/41 (100%)
Query: 206 GGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 246
GGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI
Sbjct: 41 GGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCNKI 81
Score = 83.2 bits (204), Expect = 2e-16
Identities = 41/41 (100%), Positives = 41/41 (100%)
Query: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG 41
MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG
Sbjct: 1 MNRFLLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPG 41
>gi|222136622 prostate and testis expressed 3 [Homo sapiens]
Length = 98
Score = 54.7 bits (130), Expect = 7e-08
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 1/78 (1%)
Query: 167 TILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLF 226
T L C TC +C RG G C Q + CML +I++ LQ C+ C M F
Sbjct: 19 TSLQCITCHLRTRTDRCRRGFGVCTAQKGEACMLLRIYQRNTLQISYMVCQKFCRDMT-F 77
Query: 227 SHGTRMQIICCRNQSFCN 244
R + C N ++CN
Sbjct: 78 DLRNRTYVHTCCNYNYCN 95
>gi|221554530 prostate and testis expressed 4 [Homo sapiens]
Length = 98
Score = 50.4 bits (119), Expect = 1e-06
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 2/76 (2%)
Query: 169 LNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSH 228
L C TC Y + KC+ G GTCI + ++ C F G K + C+ C
Sbjct: 23 LKCNTCIY-TEGWKCMAGRGTCIAKENELCSTTAYFRGDKHMYSTHMCKYKCREEESSKR 81
Query: 229 GTRMQIICCRNQSFCN 244
G +CC +++FCN
Sbjct: 82 GLLRVTLCC-DRNFCN 96
>gi|38261962 activating transcription factor 7 interacting protein
[Homo sapiens]
Length = 1270
Score = 50.4 bits (119), Expect = 1e-06
Identities = 36/129 (27%), Positives = 61/129 (47%)
Query: 40 PGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPA 99
PG+ + + S A +++SG T SE SS+ S T + SG+ + + SG+
Sbjct: 136 PGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDVSPGDATSGDAT 195
Query: 100 ATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQA 159
A + + G+ T + GE E +SG+ ++ S E S + SG S + S + A
Sbjct: 196 ADDLSSGDPTSSDPIPGEPVPVEPISGDCAADDIASSEITSVDLASGAPASTDPASDDLA 255
Query: 160 SGEQPSGTI 168
SG+ S +
Sbjct: 256 SGDLSSSEL 264
Score = 46.6 bits (109), Expect = 2e-05
Identities = 25/76 (32%), Positives = 39/76 (51%)
Query: 91 SEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGS 150
+E SG+PA + G+ G SG+ SG+ S E S+ SG+ S + PSG+
Sbjct: 127 AEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDVSP 186
Query: 151 GEQPSGEQASGEQPSG 166
G+ SG+ + + SG
Sbjct: 187 GDATSGDATADDLSSG 202
Score = 45.4 bits (106), Expect = 4e-05
Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 6/101 (5%)
Query: 65 LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHL 124
LS H + SK AE SG+ A + +G+PA+ A G+ T G+ S E S +
Sbjct: 112 LSPHNITPEPVSK-LPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAA 170
Query: 125 SGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
SG + SG+ PS + G+ SG+ + + +SG+ S
Sbjct: 171 SG-----DATSGDAPSGDVSPGDATSGDATADDLSSGDPTS 206
Score = 37.7 bits (86), Expect = 0.009
Identities = 33/125 (26%), Positives = 51/125 (40%)
Query: 41 GEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAA 100
G+ S E S A + +SG + + S T + +SG+ S+ GEP
Sbjct: 157 GDPTSSEPSSSDAASGDATSGDAPSGDVSPGDATSGDATADDLSSGDPTSSDPIPGEPVP 216
Query: 101 TEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS 160
E G+ + S E S + SG ++ S + S + S E S + +GE AS
Sbjct: 217 VEPISGDCAADDIASSEITSVDLASGAPASTDPASDDLASGDLSSSELASDDLATGELAS 276
Query: 161 GEQPS 165
E S
Sbjct: 277 DELTS 281
Score = 37.0 bits (84), Expect = 0.016
Identities = 19/57 (33%), Positives = 29/57 (50%)
Query: 112 EQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTI 168
E SG+ G+ +G+ L SG+ S + S E S + SG+ SG+ PSG +
Sbjct: 128 EPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGDAPSGDV 184
Score = 33.9 bits (76), Expect = 0.13
Identities = 19/69 (27%), Positives = 29/69 (42%)
Query: 98 PAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGE 157
P E G+ G+ +G+ SG + SG+ S E S + SG+ SG+
Sbjct: 119 PEPVSKLPAEPVSGDPAPGDLDAGDPASGVLASGDSTSGDPTSSEPSSSDAASGDATSGD 178
Query: 158 QASGEQPSG 166
SG+ G
Sbjct: 179 APSGDVSPG 187
>gi|4504489 histidine-rich glycoprotein precursor [Homo sapiens]
Length = 525
Score = 50.1 bits (118), Expect = 2e-06
Identities = 36/142 (25%), Positives = 48/142 (33%), Gaps = 7/142 (4%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSE-HGSS 76
G P+E S H + Q P + S A + T+ + SS+ H
Sbjct: 296 GPPPPPDERDHS--HGPPLPQGPPPLLPMSCSSCQHATFGTNGAQRHSHNNNSSDLHPHK 353
Query: 77 KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESG 136
H+ +H G H + H +H G H G P G P G H G P
Sbjct: 354 HHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHHPHGHHPHGHHPHGHHPHCHDFQD 413
Query: 137 EQPSDEQPSGE----HGSGEQP 154
P D P + HG G P
Sbjct: 414 YGPCDPPPHNQGHCCHGHGPPP 435
Score = 36.6 bits (83), Expect = 0.021
Identities = 24/105 (22%), Positives = 36/105 (34%), Gaps = 8/105 (7%)
Query: 92 EHAS-GEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGS 150
+HA+ G A H+ ++ P +H G P + + P G H
Sbjct: 328 QHATFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPH 387
Query: 151 GEQPSGEQASGEQPSGTILNCYTCAYM-------NDQGKCLRGEG 188
G P G G P G +C+ ++QG C G G
Sbjct: 388 GHHPHGHHPHGHHPHGHHPHCHDFQDYGPCDPPPHNQGHCCHGHG 432
Score = 35.8 bits (81), Expect = 0.035
Identities = 17/73 (23%), Positives = 24/73 (32%)
Query: 84 TSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQ 143
T G + H+ ++ H H+ + P G P H + G P
Sbjct: 331 TFGTNGAQRHSHNNNSSDLHPHKHHSHEQHPHGHHPHAHHPHEHDTHRQHPHGHHPHGHH 390
Query: 144 PSGEHGSGEQPSG 156
P G H G P G
Sbjct: 391 PHGHHPHGHHPHG 403
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 43.1 bits (100), Expect = 2e-04
Identities = 37/116 (31%), Positives = 42/116 (36%), Gaps = 8/116 (6%)
Query: 51 DAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTV 110
+ E E G E E G E GE E E GE E EGE
Sbjct: 839 EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGE-GEGEEEEGEGEGEEEGEGE--- 894
Query: 111 GEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
GE+ GE E GE E E GE +E+ G GE+ GE GE G
Sbjct: 895 GEEEEGEGEGEEEGEGE---GEEEEGEGKGEEEGEEGEGEGEEEEGE-GEGEDGEG 946
Score = 42.4 bits (98), Expect = 4e-04
Identities = 29/103 (28%), Positives = 42/103 (40%), Gaps = 8/103 (7%)
Query: 65 LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGE-QPSGEH 123
+ E G EHG E G+ E E GE E EGE GE+ E + E
Sbjct: 727 MEEGGEEEHGE-----GEEEEGDREEEEEKEGE--GKEEGEGEEVEGEREKEEGERKKEE 779
Query: 124 LSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G++ E E + +E+ + G ++ GE GE G
Sbjct: 780 RAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822
Score = 41.2 bits (95), Expect = 8e-04
Identities = 41/148 (27%), Positives = 52/148 (35%), Gaps = 11/148 (7%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSK 77
G + E G + + GE E + + E G E G
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDG 944
Query: 78 HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGE 137
E GE E E GE E EGE GE GE+ GE GE E E GE
Sbjct: 945 EGEGEEEEGEW-EGEEEEGEGEGEEEGEGEGEEGE-GEGEEEEGE---GE---GEEEEGE 996
Query: 138 QPSDEQPSGE---HGSGEQPSGEQASGE 162
+ +E+ GE G GE+ + GE
Sbjct: 997 EEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024
Score = 40.4 bits (93), Expect = 0.001
Identities = 41/159 (25%), Positives = 53/159 (33%), Gaps = 9/159 (5%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
G + E G + ++ GE E + E G G E
Sbjct: 840 GEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGE------QPSGEQPSGEHLSGE 127
G + GE E E E EGE GE + GE+ GE GE
Sbjct: 900 GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE-WEGE 958
Query: 128 QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+ E E E+ E GE G GE+ GE GE+ G
Sbjct: 959 EEEGEGEGEEEGEGEGEEGE-GEGEEEEGE-GEGEEEEG 995
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/105 (30%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Query: 67 EHGSSEHGSSKHTVAEHTSG---EHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEH 123
E E G K E G EH E E G+ E EGE E+ GE+ GE
Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK--EEGEGEEVEGER 768
Query: 124 LS--GEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
GE+ E E+ +E+ G+ G GE+ E E+ G
Sbjct: 769 EKEEGERKKEERAGKEEKGEEE--GDQGEGEEEETEGRGEEKEEG 811
Score = 39.7 bits (91), Expect = 0.002
Identities = 35/116 (30%), Positives = 42/116 (36%), Gaps = 10/116 (8%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
E E E + G E G G V E E E GE E EG
Sbjct: 789 EEGDQGEGEEEETEGRGEEKEEGGEVEGGE---VEEGKGEREEEEEEGEGEE---EEGEG 842
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGE 162
E GE GE+ GE GE+ E E E+ + + GE GE E+ GE
Sbjct: 843 EEEEGE---GEEEEGEG-KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894
Score = 39.3 bits (90), Expect = 0.003
Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 8/96 (8%)
Query: 69 GSSEHGSSKHTVAEHTSGEHAES-EHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGE 127
G+ E GSS AEH E E E G EGE + E+ ++ GE E
Sbjct: 657 GTCEEGSSG---AEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGE----E 709
Query: 128 QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQ 163
Q E E G Q Q E G E GE+ G++
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDR 745
Score = 39.3 bits (90), Expect = 0.003
Identities = 39/147 (26%), Positives = 53/147 (36%), Gaps = 14/147 (9%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSK 77
G + E G + +++ GE + E E +G E E G
Sbjct: 743 GDREEEEEKEGEGKEEGEGEEVEGE----REKEEGERKKEERAG----KEEKGEEEGDQG 794
Query: 78 HTVAEHTSGEHAESEHASG-EPAATEHAEGEHTVGEQPS-GEQPSGEHLSGEQPLSELES 135
E T G E E E E +GE E+ GE+ GE GE+ E E
Sbjct: 795 EGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE---GEEEEGEGEE 851
Query: 136 GEQPSDEQPSGEHGSGEQPSGEQASGE 162
E + GE G GE+ GE+ GE
Sbjct: 852 EEGEGKGEEEGEEGEGEE-EGEEGEGE 877
Score = 39.3 bits (90), Expect = 0.003
Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 5/95 (5%)
Query: 69 GSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQ 128
G E G + GE E E GE E EGE GE+ E+ GE GE
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGE---GEEEEGE-GEGEEEEGEEEGEEEGEGEE-EGEG 1011
Query: 129 PLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQ 163
E E GE + + G GE+ GE+ E+
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEER 1046
Score = 37.7 bits (86), Expect = 0.009
Identities = 36/117 (30%), Positives = 43/117 (36%), Gaps = 9/117 (7%)
Query: 41 GEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAA 100
GE E + E E G G E G + E GE E E GE
Sbjct: 944 GEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGE---GEEEEGE-GEGEEEEGEEEG 999
Query: 101 TEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGE 157
E EGE GE E+ GE + GE E E GE +E+ E G + GE
Sbjct: 1000 EEEGEGEEE-GEGEGEEEEEGE-VEGEV---EGEEGEGEGEEEEGEEEGEEREKEGE 1051
Score = 37.4 bits (85), Expect = 0.012
Identities = 34/97 (35%), Positives = 39/97 (40%), Gaps = 11/97 (11%)
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSG 126
E G E G + E E E E GE E EGE GE E+ GE G
Sbjct: 815 EGGEVEEGKGEREEEE----EEGEGEEEEGE-GEEEEGEGEEEEGEGKGEEE--GEEGEG 867
Query: 127 EQPLSELES-GEQPSDEQPSGEHGSGEQPSGEQASGE 162
E+ E E GE+ E E G GE GE+ GE
Sbjct: 868 EEEGEEGEGEGEEEEGEGEGEEEGEGE---GEEEEGE 901
Score = 37.0 bits (84), Expect = 0.016
Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 11/109 (10%)
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSG 126
EHG E E GE E E EGE E+ +G++ GE G
Sbjct: 734 EHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERK-KEERAGKEEKGEE-EG 791
Query: 127 EQPLSELESGEQPSDEQPSG--------EHGSGE-QPSGEQASGEQPSG 166
+Q E E E +E+ G E G GE + E+ GE+ G
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG 840
Score = 36.6 bits (83), Expect = 0.021
Identities = 41/157 (26%), Positives = 54/157 (34%), Gaps = 9/157 (5%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSE-HGSSEHGS 75
+G + E + + ++ GE E E E G E G E
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Query: 76 SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGE---QPSGEQPSGEHLSGEQPLSE 132
+ E GE E E GE EGE GE + GE+ GE E+ E
Sbjct: 883 GEGEGEEEGEGE-GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG-EEEEGEGE 940
Query: 133 LESGEQPSDEQP---SGEHGSGEQPSGEQASGEQPSG 166
E GE +E+ GE GE E+ GE G
Sbjct: 941 GEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEG 977
Score = 34.3 bits (77), Expect = 0.10
Identities = 31/119 (26%), Positives = 41/119 (34%), Gaps = 9/119 (7%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVG----E 112
E G G G + E E A E E E E T G +
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK 808
Query: 113 QPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEH--GSGEQPSGE---QASGEQPSG 166
+ GE GE G+ E E + +E+ GE G GE+ GE + GE+ G
Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEG 867
Score = 30.4 bits (67), Expect = 1.5
Identities = 35/145 (24%), Positives = 51/145 (35%), Gaps = 15/145 (10%)
Query: 31 DHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAE-HTSGEHA 89
D + ++ GE+ E + E E G E G + E GE
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Query: 90 ESEHASGEPAATEHAEGE---HTVGEQPSGEQPSGEHLSGEQPLSELE---SGEQ----- 138
GE E EGE GE+ GE GE GE+ E E GE+
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE---GEEEEGEEEGEEREKEGEGEENRRNR 1059
Query: 139 PSDEQPSGEHGSGEQPSGEQASGEQ 163
+E+ G++ + E+ GE+
Sbjct: 1060 EEEEEEEGKYQETGEEENERQDGEE 1084
Score = 29.6 bits (65), Expect = 2.5
Identities = 24/92 (26%), Positives = 36/92 (39%), Gaps = 12/92 (13%)
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
G + +AE + + E E E +G Q E EH GE+
Sbjct: 690 GEGEKELAEKEEWKKRDGE----EQEQKEREQGHQKERNQEMEEGGEEEHGEGEE----- 740
Query: 134 ESGEQPSDEQPSG---EHGSGEQPSGEQASGE 162
E G++ +E+ G E G GE+ GE+ E
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGEEVEGEREKEE 772
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 42.4 bits (98), Expect = 4e-04
Identities = 41/151 (27%), Positives = 59/151 (39%), Gaps = 18/151 (11%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTV 80
S ++ SG H ++ Q G F P + SSG G +H
Sbjct: 1081 SGSSQSSGYGQHGSNSGQTSG--FGQHRPGSGQ-----SSGFGQYGSGSGQSSGFGQHGS 1133
Query: 81 AEHTSGEHAESEHASGEPAATEHAEGEHT---VGEQPSGEQPS---GEHLSGEQPLSELE 134
S A+ E+ SG+ + +H G G+ SG P+ G+H+SG S
Sbjct: 1134 GTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFS--S 1191
Query: 135 SGEQPSDEQPS---GEHGSGEQPSGEQASGE 162
SG+ SD S G++GSG S GE
Sbjct: 1192 SGQHISDSGQSTGFGQYGSGSGQSTGLGQGE 1222
Score = 38.5 bits (88), Expect = 0.005
Identities = 38/158 (24%), Positives = 54/158 (34%), Gaps = 12/158 (7%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTV 80
S + SG H++S Q G + + +G S G E S + +
Sbjct: 863 SSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSY 922
Query: 81 AEHTSGEHAESEHAS-GEPAATEHAEGEHT--------VGEQPSGEQPS---GEHLSGEQ 128
+H SG S + G + G+H G+ SG S G+H SG
Sbjct: 923 GQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSG 982
Query: 129 PLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
S E S + G+HGSG S SG
Sbjct: 983 KSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSG 1020
Score = 37.7 bits (86), Expect = 0.009
Identities = 34/132 (25%), Positives = 51/132 (38%), Gaps = 21/132 (15%)
Query: 56 YETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAE--------- 105
Y + SG ++ +HGS SS E SG+ + +H+SG ++ + +
Sbjct: 583 YGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF 642
Query: 106 GEHTVGEQPS---GEQPSG--------EHLSGEQPLSELESGEQPSDEQPSGEHGSGEQP 154
G+H G S G+ SG +H+SG S E S G+HG G
Sbjct: 643 GQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQ 702
Query: 155 SGEQASGEQPSG 166
S SG
Sbjct: 703 SSGYGQHGSSSG 714
Score = 37.7 bits (86), Expect = 0.009
Identities = 39/156 (25%), Positives = 55/156 (35%), Gaps = 10/156 (6%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTV 80
S + SG H+ S Q + + SG S G E S + +
Sbjct: 711 SSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSY 770
Query: 81 AEHTSGEHAES---EHASGEPAAT-EHAEGEHT---VGEQPSGEQPS---GEHLSGEQPL 130
+H+SG S +H S + + +H G G+ SG S G+H SG
Sbjct: 771 GQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQS 830
Query: 131 SELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
S E S + G+HGSG S SG
Sbjct: 831 SGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 866
Score = 37.7 bits (86), Expect = 0.009
Identities = 37/150 (24%), Positives = 56/150 (37%), Gaps = 8/150 (5%)
Query: 21 SQPNELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKH 78
S + SG H + Q G + + S YE+ S ++ +HGS SS +
Sbjct: 1030 SSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGY 1089
Query: 79 TVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQ 138
+H S S P + + + G G G+H SG S E
Sbjct: 1090 --GQHGSNSGQTSGFGQHRPGSGQ-SSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEY 1146
Query: 139 PSDEQPSGEHGSGEQPS---GEQASGEQPS 165
S + G+HG+G S G+ SG P+
Sbjct: 1147 RSGQSSYGQHGTGSSQSSGCGQHESGSGPT 1176
Score = 37.4 bits (85), Expect = 0.012
Identities = 37/149 (24%), Positives = 61/149 (40%), Gaps = 7/149 (4%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEA----LYETSSGLNTLSEHGSSE 72
RG +++ QT + + FS + +D+E + S T S+ GS +
Sbjct: 1318 RGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGS-Q 1376
Query: 73 HGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSE 132
HG S+ TV E + ++ A+G + H + G + +G + SG S + +
Sbjct: 1377 HGESESTVHERHETTYGQTGEATGH-GHSGHGQSTQR-GSRTTGRRGSGHSESSDSEVHS 1434
Query: 133 LESGEQPSDEQPSGEHGSGEQPSGEQASG 161
S S EQ G+ GS SG G
Sbjct: 1435 GGSHRPQSQEQTHGQAGSQHGESGSTVHG 1463
Score = 37.0 bits (84), Expect = 0.016
Identities = 49/208 (23%), Positives = 76/208 (36%), Gaps = 28/208 (13%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQL--PGEFFSLENPSDAEALYETSSGLNTLSEHGSS 71
G G SS + + H ++ ++L G S N ++ Y SS ++ S G
Sbjct: 137 GEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKRYHRSSCGHSWSG-GKD 195
Query: 72 EHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLS 131
HGSS + E + H SGE E G ++ + G G SG
Sbjct: 196 RHGSSSVELRERINKSHISPSRESGE--EYESGSGSNSWERKGHGGLSCGLETSGH---- 249
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCAYMNDQGKCLRGEGTCI 191
E S + EQ G SG SG ++ + C Y N G C R +
Sbjct: 250 ESNSTQSRIREQKLGSSCSGSGDSGRRS------------HACGYSNSSG-CGRPQNA-- 294
Query: 192 TQNSQQCMLKKI-FEGGKLQFMVQGCEN 218
S C + +G + ++ GC++
Sbjct: 295 ---SSSCQSHRFGGQGNQFSYIQSGCQS 319
Score = 36.6 bits (83), Expect = 0.021
Identities = 41/170 (24%), Positives = 62/170 (36%), Gaps = 23/170 (13%)
Query: 20 SSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGSSKH 78
SS ++ SG H + G+ S + S Y + SG + +HGS SS
Sbjct: 774 SSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGF 833
Query: 79 TVAEHTSGEHAESEHASGEPAATEHAE-----------GEHT--------VGEQPSGEQP 119
E S + + +H SG ++ + + G+H G+ SG
Sbjct: 834 GQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQ 893
Query: 120 S---GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
S G+H +G S E S + G+HGSG S SG
Sbjct: 894 SSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSG 943
Score = 36.2 bits (82), Expect = 0.027
Identities = 42/160 (26%), Positives = 65/160 (40%), Gaps = 16/160 (10%)
Query: 20 SSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGSSKH 78
SS ++ SG H + G+ S + S Y + SG ++ +H S SS
Sbjct: 622 SSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGF 681
Query: 79 TVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEH-LSGEQPLSELESGE 137
E SG + +H G ++ + + + G Q SG G+H LS Q S + G
Sbjct: 682 GQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSG-QTSG---FGQHELSSGQSSSFGQHGS 737
Query: 138 QPSDEQPSGEHGSG----------EQPSGEQASGEQPSGT 167
G+HGSG E SG+ + G+ SG+
Sbjct: 738 GSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGS 777
Score = 35.8 bits (81), Expect = 0.035
Identities = 37/138 (26%), Positives = 53/138 (38%), Gaps = 14/138 (10%)
Query: 41 GEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAES---EHASGE 97
G+ S S +E+ SG + S G E SS+ +H SG S +H S
Sbjct: 962 GQHGSGSGQSSGFGQHESGSGKS--SGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSS 1019
Query: 98 PAAT-----EHAEGEHT-VGEQPSGEQPS---GEHLSGEQPLSELESGEQPSDEQPSGEH 148
T + G+++ G+ SG S G+H +G S E S + G+H
Sbjct: 1020 GQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQH 1079
Query: 149 GSGEQPSGEQASGEQPSG 166
GSG S SG
Sbjct: 1080 GSGSSQSSGYGQHGSNSG 1097
Score = 34.3 bits (77), Expect = 0.10
Identities = 31/113 (27%), Positives = 44/113 (38%), Gaps = 10/113 (8%)
Query: 50 SDAEALYETSSGLNTLSEHGS--SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGE 107
SD+E ++ S +T HG S+HG S+ V E H ++ T HA
Sbjct: 1657 SDSE-VHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDT------TRHAHYH 1709
Query: 108 HTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS 160
H + Q +G + +G SG S+ E S HG GE S
Sbjct: 1710 HGLTTQ-TGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESES 1761
Score = 34.3 bits (77), Expect = 0.10
Identities = 28/94 (29%), Positives = 44/94 (46%), Gaps = 11/94 (11%)
Query: 66 SEHGSSE-HGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHL 124
SE SE H HT + HT H+++ GE +T H + T G+ +G+ H
Sbjct: 1881 SESSDSEVHSGGSHTHSGHT---HSQARSQHGESESTVHKRHQTTHGQ--TGDTTEHGHP 1935
Query: 125 SGEQPLSELESGEQPSDEQPSG--EHGSGEQPSG 156
S Q +++G + + + SG E+ E PSG
Sbjct: 1936 SHGQ---TIQTGSRTTGRRGSGHSEYSDSEGPSG 1966
Score = 33.5 bits (75), Expect = 0.17
Identities = 28/107 (26%), Positives = 35/107 (32%), Gaps = 3/107 (2%)
Query: 56 YETSSGLNTLSE-HGSSEHGSSKHTVAEHTSGEHAESEHASGEPA-ATEHAEGEHTVGEQ 113
Y S G + +S H HG + E S H G+ A T H H Q
Sbjct: 1958 YSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQ 2017
Query: 114 PSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS 160
G + +G SG S+ E S HG GE S
Sbjct: 2018 -RGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGS 2063
Score = 31.2 bits (69), Expect = 0.86
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 15/111 (13%)
Query: 67 EHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAE---------GEHTVGEQPSGE 117
+HGS SS E S + + +H SG ++ + + G+H +G SG+
Sbjct: 520 QHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLG---SGQ 576
Query: 118 QPS-GEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGT 167
G++ SG S G+ S S G E SG+ + G+ SG+
Sbjct: 577 STGFGQYGSGSGQSSGF--GQHGSGSGQSSGFGQHESRSGQSSYGQHSSGS 625
Score = 31.2 bits (69), Expect = 0.86
Identities = 28/95 (29%), Positives = 34/95 (35%), Gaps = 9/95 (9%)
Query: 68 HGS--SEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
HG S+HG S TV G H + +G+ T HA H Q G +G S
Sbjct: 1447 HGQAGSQHGESGSTV----HGRHGTTHGQTGD--TTRHAHYHHGKSTQ-RGSSTTGRRGS 1499
Query: 126 GEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS 160
G S+ E S HG GE S
Sbjct: 1500 GHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESES 1534
Score = 31.2 bits (69), Expect = 0.86
Identities = 44/170 (25%), Positives = 55/170 (32%), Gaps = 25/170 (14%)
Query: 14 GSARGTSSQPNELSGSIDHQ-----------TSVQQLPGEFFSLENPSDAEALYETSSGL 62
G G S + S SI H T+ G + + S TS
Sbjct: 1519 GHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSE 1578
Query: 63 NTLSEHGSSEHGSSKHTVAEHTSGE----HAESEHASGEPAATEHAEGEHTVGEQPSGEQ 118
+T SE S GS + EHT G+ H E E E T H + T G SG
Sbjct: 1579 STDSEVHSG--GSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHG 1636
Query: 119 PS---GEHLSGEQPLSELESGEQP-----SDEQPSGEHGSGEQPSGEQAS 160
S G +G Q S ES + S HG G+ S
Sbjct: 1637 QSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSES 1686
Score = 31.2 bits (69), Expect = 0.86
Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 9/105 (8%)
Query: 66 SEHGSSEHGSSKHTVAEHTS---GEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
+ HG S HG S T + T H+ES + A+ G HT + S SG
Sbjct: 2155 TRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSG-HTHSQAGSRHGQSGS 2213
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPS-GEQASGEQPSG 166
G Q + ++G D +G G+ G + +G + SG
Sbjct: 2214 SGHGRQGTTHGQTG----DTTRHAHYGYGQSTQRGSRTTGRRGSG 2254
Score = 30.8 bits (68), Expect = 1.1
Identities = 29/114 (25%), Positives = 37/114 (32%), Gaps = 7/114 (6%)
Query: 59 SSGLNTLSEHGSSEHGSSKHTVAEHTSGE----HAESEHASGEPAATEHAEGEHTVGEQP 114
SSG + S+ S + HT G+ H ESE E T H + T G
Sbjct: 1800 SSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQ 1859
Query: 115 SG---EQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
SG SG +G + ES + S H GE S
Sbjct: 1860 SGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESES 1913
Score = 30.0 bits (66), Expect = 1.9
Identities = 28/92 (30%), Positives = 37/92 (40%), Gaps = 8/92 (8%)
Query: 69 GSSEHGSSKHTVA---EHTSGEHAESEHAS-GEPAATEHAEGEH-TVGEQPSGEQPSGEH 123
G +HGSS + +H SG S G + G+H +V Q SG G+H
Sbjct: 465 GYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSG---FGQH 521
Query: 124 LSGEQPLSELESGEQPSDEQPSGEHGSGEQPS 155
S S E S + G+HGSG S
Sbjct: 522 GSVSGQSSGFGQHESRSRQSSYGQHGSGSSQS 553
Score = 28.5 bits (62), Expect = 5.6
Identities = 35/127 (27%), Positives = 49/127 (38%), Gaps = 31/127 (24%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAES-EHA-SGEPAATEHAEGEHTVGEQPSGEQPSGE- 122
S+HG S GSS H T G+ ++ HA SG +T+ G T G + SG S +
Sbjct: 2056 SQHGES--GSSVHERHGTTHGQTGDTTRHAHSGHGQSTQR--GSRTAGRRGSGHSESSDS 2111
Query: 123 ------------HLSGEQPLSELESGE-----------QPSDEQPSGEHGSGEQ-PSGEQ 158
H G+ ESG Q D G+ G G+ +G +
Sbjct: 2112 EVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSR 2171
Query: 159 ASGEQPS 165
+G Q S
Sbjct: 2172 TTGRQRS 2178
Score = 27.7 bits (60), Expect = 9.5
Identities = 29/112 (25%), Positives = 41/112 (36%), Gaps = 12/112 (10%)
Query: 59 SSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQ 118
S+G G +H S + E SG+ + +H+ G Q SG
Sbjct: 577 STGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSG----SSQSSG-- 630
Query: 119 PSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPS---GEQASGE-QPSG 166
G+H Q + G S G++GSG S G+ SG Q SG
Sbjct: 631 -YGQH-GSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSG 680
Score = 27.7 bits (60), Expect = 9.5
Identities = 33/148 (22%), Positives = 52/148 (35%), Gaps = 12/148 (8%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHG 74
S G S+Q + + + E S +P+ + + + S HG S G
Sbjct: 2160 SGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAG-----SRHGQS--G 2212
Query: 75 SSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE---HLSGEQPLS 131
SS H T G+ ++ + G T G + SG S + H G S
Sbjct: 2213 SSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHS 2272
Query: 132 ELESGEQPSDEQPSGE--HGSGEQPSGE 157
G+ S ++ G HG E G+
Sbjct: 2273 GHIQGQAGSQQRQPGSTVHGRLETTHGQ 2300
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 42.0 bits (97), Expect = 5e-04
Identities = 43/154 (27%), Positives = 62/154 (40%), Gaps = 9/154 (5%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGS 75
RG+ S+ + G + G+ S S +E+SSG ++ S+HGS S
Sbjct: 1131 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1190
Query: 76 SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLSE 132
S + SG+ + E ++ H G+H G + S G Q SG SG P S
Sbjct: 1191 SGYGQHGSRSGQSSRGERHGSSSGSSSH-YGQHGSGSRQSSGHGRQGSG---SGHSP-SR 1245
Query: 133 LESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
G G+HGSG S + E SG
Sbjct: 1246 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSG 1279
Score = 41.6 bits (96), Expect = 6e-04
Identities = 44/155 (28%), Positives = 66/155 (42%), Gaps = 11/155 (7%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGS 75
RG+ S+ + G + G+ S S +E+SSG ++ S+HGS S
Sbjct: 1601 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 1660
Query: 76 SKHTVAEHTSGEHAESE-HASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLS 131
S + SG+ + E H S +++ + G+H G + S G Q SG SG+ P S
Sbjct: 1661 SGYGQHGSRSGQSSRGERHGSSSRSSSRY--GQHGSGSRQSSGHGRQGSG---SGQSP-S 1714
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
G G+HGSG S + E SG
Sbjct: 1715 RGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSG 1749
Score = 41.2 bits (95), Expect = 8e-04
Identities = 46/155 (29%), Positives = 63/155 (40%), Gaps = 14/155 (9%)
Query: 16 ARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHG 74
+R + S SGS +S Q PG S +E+SSG ++ S+HGS
Sbjct: 2075 SRQSPSYGRHGSGSGRSSSSGQHGPGL-----GESSGFGHHESSSGQSSSYSQHGSGSGH 2129
Query: 75 SSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLS 131
SS + SG+ + E G + + G+H G + S G Q SG SG P S
Sbjct: 2130 SSGYGQHGSRSGQSSRGER-HGSSSGSSSRYGQHGSGSRQSSGHGRQGSG---SGHSP-S 2184
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
G G+HGSG S + E SG
Sbjct: 2185 RGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
Score = 40.8 bits (94), Expect = 0.001
Identities = 50/172 (29%), Positives = 69/172 (40%), Gaps = 30/172 (17%)
Query: 14 GSARGTSSQPNE-LSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-------- 64
GS G S P+ GS Q+S G + S S + YE+ SG ++
Sbjct: 1000 GSGSGQSPSPSRGRHGSGSGQSSSY---GPYRSGSGWSSSRGPYESGSGHSSGLGHRESR 1056
Query: 65 ------LSEHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQPS-- 115
+HGSS SS H TSG+ + +H + ++ H G+H G S
Sbjct: 1057 SGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH--GQHGSGSSQSSG 1114
Query: 116 -GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
G Q SG SG+ P + G G HGSG S +SG+ SG
Sbjct: 1115 YGRQGSG---SGQSP-GHGQRGSGSRQSPSYGRHGSGSGRS--SSSGQHGSG 1160
Score = 40.4 bits (93), Expect = 0.001
Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 9/115 (7%)
Query: 56 YETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQP 114
+++ SG ++ S+HGS SS + SG+ + SE G + + G+H G
Sbjct: 703 HKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQ-HGSSSGLSSSYGQHGSGSHQ 761
Query: 115 S---GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
S G Q SG SG P S + G G+HGSG S E SG
Sbjct: 762 SSGHGRQGSG---SGHSP-SRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSG 812
Score = 40.4 bits (93), Expect = 0.001
Identities = 42/154 (27%), Positives = 62/154 (40%), Gaps = 9/154 (5%)
Query: 17 RGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGS 75
RG+ S+ + G + G+ S S +E+SSG ++ S+HGS S
Sbjct: 2541 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHS 2600
Query: 76 SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLSE 132
S + SG+ + E ++ H G+H G + S G Q SG SG+ P S
Sbjct: 2601 SGYGQHGSRSGQSSRGERHGSSSGSSSH-YGQHGSGSRQSSGHGRQGSG---SGQSP-SR 2655
Query: 133 LESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
G G+HGSG S + E G
Sbjct: 2656 GRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLG 2689
Score = 39.7 bits (91), Expect = 0.002
Identities = 46/158 (29%), Positives = 65/158 (41%), Gaps = 17/158 (10%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSE 72
GS G SS + +S G + S + S E+ SG ++ +HGSS
Sbjct: 1485 GSGSGQSSSYSPYGSGSGWSSS----RGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSS 1540
Query: 73 HGSSKHTVAEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQ 128
SS H TSG+ + +H + ++ H G+H G S G Q SG SG+
Sbjct: 1541 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH--GQHGSGSSQSSGYGRQGSG---SGQS 1595
Query: 129 PLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
P + G G HGSG S +SG+ SG
Sbjct: 1596 P-GHGQRGSGSRQSPSYGRHGSGSGRS--SSSGQHGSG 1630
Score = 39.3 bits (90), Expect = 0.003
Identities = 45/158 (28%), Positives = 65/158 (41%), Gaps = 22/158 (13%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLS-EHGSSEHGSSKHT 79
S + SG H++ Q + S ++ + ++SG ++ S +H SS SS +
Sbjct: 809 SGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSY- 867
Query: 80 VAEHTSGEHAES---EHASGEPAATEHAEGEHTVGEQPS---------GEQPSGEHLSGE 127
+H S H S H SG + H + G+ PS SG H SG
Sbjct: 868 -GQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGS 926
Query: 128 QPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQ 163
S G + S Q SG +HGSG SG +S EQ
Sbjct: 927 GQSSGF--GHKSSSGQSSGYTQHGSG---SGHSSSYEQ 959
Score = 39.3 bits (90), Expect = 0.003
Identities = 37/115 (32%), Positives = 52/115 (45%), Gaps = 13/115 (11%)
Query: 57 ETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQP 114
E+ SG ++ +HGSS SS H TSG+ + +H + ++ H G+H G
Sbjct: 2464 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSH--GQHGSGSSQ 2521
Query: 115 S---GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
S G Q SG SG+ P + G G HGSG S +SG+ SG
Sbjct: 2522 SSGYGRQGSG---SGQSP-GHGQRGSGSRQSPSYGRHGSGSGRS--SSSGQHGSG 2570
Score = 38.9 bits (89), Expect = 0.004
Identities = 44/155 (28%), Positives = 65/155 (41%), Gaps = 15/155 (9%)
Query: 18 GTSSQPNE-LSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGS 75
G+ PN GS Q+S G S S + +++SSG ++ S+HGS S
Sbjct: 198 GSGQSPNYGQHGSGSGQSSSNDTHG---SGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHS 254
Query: 76 SKHTVAEHTSGEHAESE-HASGEPAATEHAEGEHTVGEQPS---GEQPSGEHLSGEQPLS 131
S + SG+ + E H S +++ + G+H G + S G Q SG Q S
Sbjct: 255 SGYGQHGSRSGQSSRGERHRSSSGSSSSY--GQHGSGSRQSLGHGRQGSGSR----QSPS 308
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+ G G+HGSG S + E SG
Sbjct: 309 HVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSG 343
Score = 38.1 bits (87), Expect = 0.007
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 8/149 (5%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEHGSS 76
G+ S + G +S G + S + +E+ SG ++ S+HGS SS
Sbjct: 313 GSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSS 372
Query: 77 KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGE-QPLSELES 135
TSG+ A S G + + G+H + S + G+H SG Q +
Sbjct: 373 SQGQHGSTSGQ-ASSSGQHGSSSRQSSSYGQHESASRHSSGR--GQHSSGSGQSPGHGQR 429
Query: 136 GEQPSDEQPSGEHGSG---EQPSGEQASG 161
G SG+HG+G SG SG
Sbjct: 430 GSGSGQSPSSGQHGTGFGRSSSSGPYVSG 458
Score = 38.1 bits (87), Expect = 0.007
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 11/115 (9%)
Query: 57 ETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQP 114
E+ SG ++ +HGSS SS H TSG+ + +H + ++ H G+H G
Sbjct: 588 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSH--GQHGSGSSQ 645
Query: 115 S---GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
S G+Q SG SG+ P S G G+HGSG S SG
Sbjct: 646 SSRYGQQGSG---SGQSP-SRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSG 696
Score = 38.1 bits (87), Expect = 0.007
Identities = 33/112 (29%), Positives = 51/112 (45%), Gaps = 14/112 (12%)
Query: 56 YETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQP 114
+++SSG ++ ++HGS SS + SG+ + SE G + + + G+H G +
Sbjct: 934 HKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQ-HGSSSGSSSSYGQHGSGSRQ 992
Query: 115 SGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
S G+H SG SG+ PS + G HGSG S SG
Sbjct: 993 S--LGHGQHGSG--------SGQSPSPSR--GRHGSGSGQSSSYGPYRSGSG 1032
Score = 37.4 bits (85), Expect = 0.012
Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 18/163 (11%)
Query: 14 GSARGTSSQPNE-LSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSE 72
GS G S P+ GS Q+S G + S S + YE+ SG ++ H S
Sbjct: 1940 GSGSGQSPSPSRGRHGSGSGQSSSY---GPYGSGSGWSSSRGPYESGSGHSSGLGHRESR 1996
Query: 73 HGSS----KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQ 128
G S +H + S H + ASG+ ++ G+H G G+H SG
Sbjct: 1997 SGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC----GQH--GASSGQSSSHGQHGSGSS 2050
Query: 129 PLSELESGEQPSDEQPS-GEHGSGEQPS---GEQASGEQPSGT 167
S S + P G+ GSG + S G SG S +
Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 2093
Score = 37.0 bits (84), Expect = 0.016
Identities = 41/162 (25%), Positives = 60/162 (37%), Gaps = 18/162 (11%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
G G+SS+ + G H + +Q G + + SGL S HG
Sbjct: 1676 GERHGSSSRSSSRYGQ--HGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS 1733
Query: 74 GSSKHTVA---EHTSGEHA---ESEHASGEPAA-TEHAEGEHTVGEQPSGEQPSGEHLSG 126
GS + + E SG + + E SG +A ++H G Q SG+ +
Sbjct: 1734 GSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 1793
Query: 127 EQPLSELESGEQPSDEQPSGEHGSGEQPS---GEQASGEQPS 165
+Q G G+HGSG S G+Q SG S
Sbjct: 1794 DQ------EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 1829
Score = 37.0 bits (84), Expect = 0.016
Identities = 44/160 (27%), Positives = 65/160 (40%), Gaps = 18/160 (11%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTL-SEHGSSE 72
GS+ G+SS+ + GS Q+S G S S + + + SG ++ +HGS
Sbjct: 2150 GSSSGSSSRYGQ-HGSGSRQSSGHGRQG---SGSGHSPSRGRHGSGSGHSSSHGQHGSGS 2205
Query: 73 HGSSKHTVAEHTSGEHA---ESEHASGEPAA-TEHAEGEHTVGEQPSGEQPSGEHLSGEQ 128
SS E SG + + E SG +A ++H G Q SG+ + +Q
Sbjct: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
Query: 129 PLSELESGEQPSDEQPSGEHGSGEQPS---GEQASGEQPS 165
G G+HGSG S G+Q SG S
Sbjct: 2266 ------EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQS 2299
Score = 35.0 bits (79), Expect = 0.060
Identities = 35/114 (30%), Positives = 55/114 (48%), Gaps = 18/114 (15%)
Query: 56 YETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQP 114
+E+SS ++ ++HGS SS + SG+ + E G + + + G+H G +
Sbjct: 1874 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQ-HGSSSGSSSSYGQHGSGSRQ 1932
Query: 115 SGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS-GEQPSGT 167
S G+H SG SG+ PS + G HGSG SG+ +S G SG+
Sbjct: 1933 S--LGHGQHGSG--------SGQSPSPSR--GRHGSG---SGQSSSYGPYGSGS 1971
Score = 35.0 bits (79), Expect = 0.060
Identities = 35/113 (30%), Positives = 54/113 (47%), Gaps = 18/113 (15%)
Query: 56 YETSSGLNT-LSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQP 114
+E+SS ++ ++HGS SS + SG+ + E G + + + G+H G +
Sbjct: 2344 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGER-HGSSSGSSSSYGQHGSGSRQ 2402
Query: 115 SGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGT 167
S G+H SG SG+ PS + G HGSG SG Q+S P G+
Sbjct: 2403 S--LGHGQHGSG--------SGQSPSPSR--GRHGSG---SG-QSSSYSPYGS 2439
Score = 34.7 bits (78), Expect = 0.078
Identities = 45/163 (27%), Positives = 64/163 (39%), Gaps = 21/163 (12%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
GS G S + H +S G+ S S + YE+ G +++ G E
Sbjct: 2646 GSGSGQSPSRGRHGSGLGHSSS----HGQHGSGSGRSSSRGPYESRLGHSSV--FGQHES 2699
Query: 74 GSSKHTV-AEHTSGEH---AESEHASGE-PAATEHAEGEHT-----VGEQPSGEQPS--- 120
GS + ++H SG ++ +H S ++T EG T G + SG S
Sbjct: 2700 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGY 2759
Query: 121 GEHLSGE-QPLSELESGEQPSDEQPSGEHGSGE-QPSGEQASG 161
G H +G Q LS G G+HGSG Q SG G
Sbjct: 2760 GRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHG 2802
Score = 33.9 bits (76), Expect = 0.13
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 6/102 (5%)
Query: 63 NTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
++ +HGS SS + SG+ + H SG ++ ++ +H G S
Sbjct: 673 SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYS--QHGSGSSHSSGYRKHG 730
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPS---GEQASG 161
SG+ SE + G G+HGSG S G Q SG
Sbjct: 731 SRSGQSSRSE-QHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG 771
Score = 33.1 bits (74), Expect = 0.23
Identities = 36/153 (23%), Positives = 53/153 (34%), Gaps = 12/153 (7%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTV 80
S + SG H + Q PG + + SG S G GS + +
Sbjct: 872 SASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSG 931
Query: 81 AEHTSGEHAES---EHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGE 137
H S S +H SG ++ + + G+ EQ G S G+
Sbjct: 932 FGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQ------HGSSSGSSSSYGQ 985
Query: 138 QPSDEQPS---GEHGSGEQPSGEQASGEQPSGT 167
S + S G+HGSG S + G SG+
Sbjct: 986 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1018
Score = 33.1 bits (74), Expect = 0.23
Identities = 43/168 (25%), Positives = 67/168 (39%), Gaps = 20/168 (11%)
Query: 14 GSARGTSSQ-------PNELSGSIDHQTSVQQLP--GEFFSLENPSDAEALYETSSGLNT 64
GS+ G SS ++ SG H Q P G S S + + + SG ++
Sbjct: 1327 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSS 1386
Query: 65 LS-EHGSSEHGSSKHTVAEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
S HGS SS E +S + + ++H SG ++ + + G+ GE+
Sbjct: 1387 SSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGER---- 1442
Query: 123 HLSGEQPLSELESGEQPSDEQPS---GEHGSGEQPSGEQASGEQPSGT 167
G S G+ S + S G+HGSG S + G SG+
Sbjct: 1443 --HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1488
Score = 32.0 bits (71), Expect = 0.51
Identities = 42/148 (28%), Positives = 57/148 (38%), Gaps = 24/148 (16%)
Query: 14 GSARGTSS----QPNELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNTLSE 67
GS R +SS + S H++S Q G + S S + + + SG ++ SE
Sbjct: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSE 971
Query: 68 -HGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSG 126
HGSS SS + +H SG + H G+H G S G H SG
Sbjct: 972 QHGSSSGSSSSY------------GQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRHGSG 1017
Query: 127 EQPLSE---LESGEQPSDEQPSGEHGSG 151
S SG S + E GSG
Sbjct: 1018 SGQSSSYGPYRSGSGWSSSRGPYESGSG 1045
Score = 31.6 bits (70), Expect = 0.66
Identities = 43/176 (24%), Positives = 65/176 (36%), Gaps = 29/176 (16%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT-LSEHGSSEH 73
S+ G SS ++ H + G+ S S + +SSG ++ +HGS
Sbjct: 236 SSSGQSSGYSQHGSGSGHSSGY----GQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSR 291
Query: 74 GSSKH-----------TVAEHTSGE-HAESEHASGEPAATEHAEGEHTVGE-QPSG---- 116
S H + H SG H+ S G ++ ++ G + G Q SG
Sbjct: 292 QSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQH 351
Query: 117 EQPSGE------HLSGE-QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
E SG+ H SG S+ + G SG+HGS + S E S
Sbjct: 352 ESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESAS 407
Score = 30.4 bits (67), Expect = 1.5
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 20/116 (17%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGE-PAATEHAEG---EHTVGE 112
+ S S HG GSS+ S + + SG+ P+ H G + G+
Sbjct: 1795 QEGSSTGQSSSHGQHGSGSSQ-------SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ 1847
Query: 113 QPSG---EQPSGEHLSGEQPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQ 163
SG SG H SG S E S Q SG +HGSG SG +S EQ
Sbjct: 1848 HGSGSGWSSSSGRHGSGSGQSSGFGHHES-SSWQSSGYTQHGSG---SGHSSSYEQ 1899
Score = 30.4 bits (67), Expect = 1.5
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 20/116 (17%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGE-PAATEHAEG---EHTVGE 112
+ S S HG GSS+ S + + SG+ P+ H G + G+
Sbjct: 2265 QEGSSTGQSSSHGQHGSGSSQ-------SSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQ 2317
Query: 113 QPSG---EQPSGEHLSGEQPLSELESGEQPSDEQPSG--EHGSGEQPSGEQASGEQ 163
SG SG H SG S E S Q SG +HGSG SG +S EQ
Sbjct: 2318 HGSGSGWSSSSGRHGSGSGQSSGFGHHES-SSWQSSGYTQHGSG---SGHSSSYEQ 2369
Score = 30.0 bits (66), Expect = 1.9
Identities = 44/164 (26%), Positives = 58/164 (35%), Gaps = 25/164 (15%)
Query: 14 GSARGTSSQPN-------ELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNT 64
GS G SS + SG H++S Q G + S S + + + SG ++
Sbjct: 1379 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSS 1438
Query: 65 LSE-HGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEH 123
E HGSS SS + +H SG + H G+H G S G H
Sbjct: 1439 RGERHGSSSGSSSSY------------GQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRH 1484
Query: 124 LSGE-QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
SG Q S G G + SG S E SG
Sbjct: 1485 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSG 1528
Score = 30.0 bits (66), Expect = 1.9
Identities = 42/151 (27%), Positives = 56/151 (37%), Gaps = 27/151 (17%)
Query: 14 GSARGTSSQPN-------ELSGSIDHQTSVQQLPG--EFFSLENPSDAEALYETSSGLNT 64
GS G SS + SG H++S Q G + S S + + + SG ++
Sbjct: 2319 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 2378
Query: 65 LSE-HGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEH 123
E HGSS SS + +H SG + H G+H G S G H
Sbjct: 2379 RGERHGSSSGSSSSY------------GQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRH 2424
Query: 124 LSG---EQPLSELESGEQPSDEQPSGEHGSG 151
SG S SG S + E GSG
Sbjct: 2425 GSGSGQSSSYSPYGSGSGWSSSRGPYESGSG 2455
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 42.0 bits (97), Expect = 5e-04
Identities = 33/130 (25%), Positives = 46/130 (35%), Gaps = 11/130 (8%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAE- 105
E P +E E G + E G A T G H E+E G P E +
Sbjct: 39 EGPEGSEGAEEAPRGAAAVKEAGGGGPDRGPEAEARGTRGAHGETEAEEGAPEGAEVPQG 98
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELE---------SGEQPSDEQPSGEHGSGEQPSG 156
GE T G Q G GE P E + ++ ++++P GS +G
Sbjct: 99 GEETSGAQQVEGASPGRGAQGE-PRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAG 157
Query: 157 EQASGEQPSG 166
+ E P G
Sbjct: 158 DSVDAEGPLG 167
Score = 42.0 bits (97), Expect = 5e-04
Identities = 35/169 (20%), Positives = 66/169 (39%), Gaps = 16/169 (9%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLP-----------GEFFSLENPSDAEALYETSSGL 62
G RG + + E S + + Q +Q P G+ E P E +G
Sbjct: 119 GEPRGEAQREPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGD 178
Query: 63 NTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
+ +E + ++ + E ++ E A + + E VG+ E P+G+
Sbjct: 179 SVEAEGRVGDSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSVDAEGPAGD 238
Query: 123 HLSGEQPLSE-LESGEQPSDEQ----PSGEHGSGEQPSGEQASGEQPSG 166
+ E + + +E+G+ D P+G+ E P+G+ E P+G
Sbjct: 239 SVDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAG 287
>gi|19923082 expressed in prostate and testis [Homo sapiens]
Length = 126
Score = 40.4 bits (93), Expect = 0.001
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 10/84 (11%)
Query: 168 ILNCYTCAYMNDQGKCLRGEGTCITQNSQQCMLKKIFE-GGKLQFMVQGCENMCPSMNLF 226
I+ C C KC RG G C + CM+ ++F+ G GC C +
Sbjct: 45 IVQCRMCHLQFPGEKCSRGRGICTATTEEACMVGRMFKRDGNPWLTFMGCLKNCADVK-- 102
Query: 227 SHGTRMQII-----CCRNQSFCNK 245
G R + CCR+ CN+
Sbjct: 103 --GIRWSVYLVNFRCCRSHDLCNE 124
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 40.0 bits (92), Expect = 0.002
Identities = 34/138 (24%), Positives = 55/138 (39%), Gaps = 10/138 (7%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
+++ SS +S H A ++GE S H ++ H+ H G+ S + SG S
Sbjct: 685 TQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGH--GQASSAVRDSGHRGS 742
Query: 126 GEQPLSELESGEQPSDEQ------PSGEHGSGEQPSGEQASGEQP--SGTILNCYTCAYM 177
++ E + SD Q +G H Q S SGE+ SG+ L +
Sbjct: 743 SGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQ 802
Query: 178 NDQGKCLRGEGTCITQNS 195
++ G T + Q S
Sbjct: 803 SESSHGWTGPSTGVRQGS 820
Score = 36.6 bits (83), Expect = 0.021
Identities = 28/114 (24%), Positives = 44/114 (38%), Gaps = 11/114 (9%)
Query: 57 ETSSGLNTLSEHGSS---EHGSSKHTV-AEHTSGEHAESEHASGEPAATE-------HAE 105
E SSG T GSS + S +H+ +E SG + + H S + + H E
Sbjct: 1255 EQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQE 1314
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQA 159
+ G + SG H + + S + + P HGS Q S + +
Sbjct: 1315 DRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS 1368
Score = 36.2 bits (82), Expect = 0.027
Identities = 39/155 (25%), Positives = 61/155 (39%), Gaps = 5/155 (3%)
Query: 14 GSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
GS+R + E +GS + + + S + D+E E++S + S S H
Sbjct: 1569 GSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRH 1628
Query: 74 GS---SKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPL 130
GS H + G AES SG A + G+ ++ + P H S Q
Sbjct: 1629 GSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQS 1688
Query: 131 SELESGEQPSDEQPSGEHG-SGEQ-PSGEQASGEQ 163
++ + Q S G SG + SG QAS +
Sbjct: 1689 ADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSE 1723
Score = 34.3 bits (77), Expect = 0.10
Identities = 39/184 (21%), Positives = 62/184 (33%), Gaps = 22/184 (11%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPS-------------DAEALYETSSG 61
S RG S+ + SGS +Q S + PS D+ + G
Sbjct: 3695 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEG 3754
Query: 62 LNTLSEHGSSEHGSSKHTVAEHT------SGEHAESEHASGEPAATEHAEGEHTVGEQPS 115
+T+ H S G + + E + SG H + G A+ G + +
Sbjct: 3755 QDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETR 3814
Query: 116 GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTILNCYTCA 175
E+ SG+ S +D + G GE +G + S Q S + + A
Sbjct: 3815 NEEQSGD--GSRHSGSRHHEASTQADSSRHSQSGQGES-AGSRRSRRQGSSVSQDSDSEA 3871
Query: 176 YMND 179
Y D
Sbjct: 3872 YPED 3875
Score = 33.5 bits (75), Expect = 0.17
Identities = 38/170 (22%), Positives = 57/170 (33%), Gaps = 22/170 (12%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSL-------------ENPSDAEALYETSSG 61
S RG S + + SGS +Q S + P E D+ + G
Sbjct: 453 STRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEG 512
Query: 62 LNTLSEHGSSEHGSSKHTVAEHT------SGEHAESEHASGEPAATEHAEGEHTVGEQPS 115
+T+ H S G + + E + SG H + G A+ G + Q
Sbjct: 513 QDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 572
Query: 116 GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
E+ SG+ S +D + G G Q SG + S Q S
Sbjct: 573 NEEQSGD--GTRHSGSRHHEASSQADSSRHSQVGQG-QSSGPRTSRNQGS 619
Score = 32.7 bits (73), Expect = 0.30
Identities = 43/176 (24%), Positives = 62/176 (35%), Gaps = 31/176 (17%)
Query: 16 ARGTSSQPNELSGSI--DHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
++G S SGS +H+ S Q+ S + + +E +G +E SS
Sbjct: 3545 SQGHSEDSERWSGSASRNHRGSAQEQ-----SRDGSRHPTSHHEDRAGHGHSAE--SSRQ 3597
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTV------------GEQPSGEQPSG 121
+ H AE++SG A S H +A E H G+ S + SG
Sbjct: 3598 SGTHH--AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 3655
Query: 122 EHLSGEQPLSELESGEQPSDEQPSGEHGSG--------EQPSGEQASGEQPSGTIL 169
S S+ E + SD Q HG E G A SG+ L
Sbjct: 3656 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFL 3711
Score = 32.3 bits (72), Expect = 0.39
Identities = 26/100 (26%), Positives = 40/100 (40%), Gaps = 5/100 (5%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
+E S +S H A ++GE S H ++ H+ H G+ S + SG
Sbjct: 1982 TESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGH--GQASSAVRDSGHRGY 2039
Query: 126 GEQPLSELESGEQPSDEQ---PSGEHGSGEQPSGEQASGE 162
S+ E + SD Q G+ G +Q E A G+
Sbjct: 2040 SGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQ 2079
Score = 32.3 bits (72), Expect = 0.39
Identities = 43/176 (24%), Positives = 60/176 (34%), Gaps = 31/176 (17%)
Query: 16 ARGTSSQPNELSGSI--DHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEH 73
+ G S SGS +H S Q+ S + + +E +G +E SS
Sbjct: 2249 SEGHSEDSERRSGSASRNHHGSAQEQ-----SRDGSRHPRSHHEDRAGHGHSAE--SSRQ 2301
Query: 74 GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTV------------GEQPSGEQPSG 121
+ H AE++SG A S H +A E H G+ S + SG
Sbjct: 2302 SGTHH--AENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSG 2359
Query: 122 EHLSGEQPLSELESGEQPSDEQPSGEHGSG--------EQPSGEQASGEQPSGTIL 169
S S+ E + SD Q HG E G A SG+ L
Sbjct: 2360 HRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFL 2415
Score = 32.3 bits (72), Expect = 0.39
Identities = 29/127 (22%), Positives = 44/127 (34%), Gaps = 19/127 (14%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPS-------------DAEALYETSSG 61
SARG S + + SGS +Q S + PS D+ + G
Sbjct: 2723 SARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDG 2782
Query: 62 LNTLSEHGSSEHGSSKHTVAEHT------SGEHAESEHASGEPAATEHAEGEHTVGEQPS 115
+T+ H S G + EH+ SG H + G A+ G +
Sbjct: 2783 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 2842
Query: 116 GEQPSGE 122
E+ SG+
Sbjct: 2843 NEEQSGD 2849
Score = 32.0 bits (71), Expect = 0.51
Identities = 28/134 (20%), Positives = 48/134 (35%), Gaps = 3/134 (2%)
Query: 32 HQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAES 91
HQ S Q+ ++ + +Y+ S+ + S HG + + + + H +
Sbjct: 1095 HQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 1154
Query: 92 EHASGEPAATEHAE-GEHTVGEQPSGEQPSGEHL--SGEQPLSELESGEQPSDEQPSGEH 148
AS E T A G G Q S + S + SG G + SG
Sbjct: 1155 HSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSR 1214
Query: 149 GSGEQPSGEQASGE 162
+ Q ++ SG+
Sbjct: 1215 SASRQTRKDKQSGD 1228
Score = 31.6 bits (70), Expect = 0.66
Identities = 29/127 (22%), Positives = 44/127 (34%), Gaps = 19/127 (14%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPS-------------DAEALYETSSG 61
SARG S + + SGS +Q S + PS D+ + G
Sbjct: 3047 SARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYG 3106
Query: 62 LNTLSEHGSSEHGSSKHTVAEHT------SGEHAESEHASGEPAATEHAEGEHTVGEQPS 115
+T+ H S G + EH+ SG H + G A+ G +
Sbjct: 3107 QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 3166
Query: 116 GEQPSGE 122
E+ SG+
Sbjct: 3167 NEEQSGD 3173
Score = 31.2 bits (69), Expect = 0.86
Identities = 38/149 (25%), Positives = 55/149 (36%), Gaps = 32/149 (21%)
Query: 45 SLENPSDAEALYETS---SGLNTLSEHGSSEHGS---SKHTVAEHTS----GEHAESEHA 94
S+ SD+E E S SG + + GS++ S S+H + H G A+S
Sbjct: 945 SVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQ 1004
Query: 95 SGEP---------AATEHAEGEHTVGE------QPSGEQPSGEHLSGEQPLSEL------ 133
SG P AA+ H + + GE Q S + + Q S +
Sbjct: 1005 SGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQASSAVRDSGHW 1064
Query: 134 -ESGEQPSDEQPSGEHGSGEQPSGEQASG 161
SG Q SD + E + SG G
Sbjct: 1065 GSSGSQASDSEGHSEESDTQSVSGHGQDG 1093
Score = 30.8 bits (68), Expect = 1.1
Identities = 39/125 (31%), Positives = 52/125 (41%), Gaps = 35/125 (28%)
Query: 45 SLENPSDAEALYETS---SGLNTLSEHGSSEHGS---SKHTVAEHTS----GEHAESEHA 94
S+ SD+E E S SG + + HGS++ S S+H + H G AES
Sbjct: 2242 SVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQ 2301
Query: 95 SGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQP 154
SG T HAE SG Q + H EQ S +GE+ HGS Q
Sbjct: 2302 SG----THHAENS-------SGGQAASSH---EQARSS--AGER---------HGSHHQQ 2336
Query: 155 SGEQA 159
S + +
Sbjct: 2337 SADSS 2341
Score = 30.4 bits (67), Expect = 1.5
Identities = 34/134 (25%), Positives = 48/134 (35%), Gaps = 30/134 (22%)
Query: 57 ETSSGLNTLSEHGSS------EHG--------SSKHTVAEHTSGEHAESEH----ASGEP 98
ETSS T S H + HG SS+H+ A S+ +SG
Sbjct: 362 ETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQ 421
Query: 99 AATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQ-----------PSDEQPSGE 147
A+ E++ + SG +G Q + SGE+ + EQP
Sbjct: 422 ASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSA 481
Query: 148 HG-SGEQPSGEQAS 160
HG +G G Q S
Sbjct: 482 HGRTGTSTGGRQGS 495
Score = 30.4 bits (67), Expect = 1.5
Identities = 27/109 (24%), Positives = 40/109 (36%), Gaps = 5/109 (4%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG---EHTVGEQPSGEQPSGE 122
+E S +S A + GE S H ++T+ G + +V SG
Sbjct: 1658 AETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGS 1717
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQP--SGTIL 169
S + SE + S +G H Q S SGE+ SG+ L
Sbjct: 1718 QASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFL 1766
Score = 30.4 bits (67), Expect = 1.5
Identities = 25/103 (24%), Positives = 37/103 (35%), Gaps = 9/103 (8%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
++ S +S H A ++GE S H ++ G G+ S + SG
Sbjct: 2631 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQASSAVRDSGHRGY 2687
Query: 126 GEQPLSELESGEQPSDEQP------SGEHGSGEQPSGEQASGE 162
S+ E + SD Q +G H Q S SGE
Sbjct: 2688 SGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGE 2730
Score = 30.4 bits (67), Expect = 1.5
Identities = 25/103 (24%), Positives = 37/103 (35%), Gaps = 9/103 (8%)
Query: 66 SEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLS 125
++ S +S H A ++GE S H ++ G G+ S + SG
Sbjct: 2955 TQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQASSAVRDSGHRGY 3011
Query: 126 GEQPLSELESGEQPSDEQP------SGEHGSGEQPSGEQASGE 162
S+ E + SD Q +G H Q S SGE
Sbjct: 3012 SGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGE 3054
Score = 30.0 bits (66), Expect = 1.9
Identities = 22/98 (22%), Positives = 35/98 (35%), Gaps = 8/98 (8%)
Query: 70 SSEHGSSKHTV-AEHTSGEHAESEHAS-------GEPAATEHAEGEHTVGEQPSGEQPSG 121
S + S H+ +E SG + + H S G H E + G + SG
Sbjct: 298 SQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSG 357
Query: 122 EHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQA 159
+ + S + + P HGSG Q S + +
Sbjct: 358 TRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSS 395
Score = 29.6 bits (65), Expect = 2.5
Identities = 28/134 (20%), Positives = 46/134 (34%), Gaps = 3/134 (2%)
Query: 32 HQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAES 91
HQ S Q+ + + LY+ S+ + S HG + + + + H +
Sbjct: 3364 HQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 3423
Query: 92 EHASGEPAATEHAE-GEHTVGEQPSGEQPSGEHL--SGEQPLSELESGEQPSDEQPSGEH 148
AS E T G G Q S + S + SG G + SG
Sbjct: 3424 HSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR 3483
Query: 149 GSGEQPSGEQASGE 162
+ Q ++ SG+
Sbjct: 3484 SASRQTRNDEQSGD 3497
Score = 29.3 bits (64), Expect = 3.3
Identities = 28/118 (23%), Positives = 44/118 (37%), Gaps = 14/118 (11%)
Query: 55 LYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQP 114
LY+ SS + S HG + + + H ++ AS +G+ T+ P
Sbjct: 1442 LYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSAS--------QDGQDTIRGHP 1493
Query: 115 SGEQPSGEHLSGEQPLSEL-ESGEQPSDEQPSG----EHG-SGEQPSGEQASGEQPSG 166
+ + EQ + SG S P G HG SG + + Q E+ SG
Sbjct: 1494 GSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSG 1551
Score = 28.9 bits (63), Expect = 4.3
Identities = 28/111 (25%), Positives = 39/111 (35%), Gaps = 14/111 (12%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSG 116
+TSSG +S H A ++GE S H ++ G G+ S
Sbjct: 2632 QTSSGGQ----------AASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQASSA 2678
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPSGEHG-SGEQPSGEQASGEQPSG 166
+ SG S+ E + SD Q HG +G Q S SG
Sbjct: 2679 VRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSG 2729
Score = 28.9 bits (63), Expect = 4.3
Identities = 28/111 (25%), Positives = 39/111 (35%), Gaps = 14/111 (12%)
Query: 57 ETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSG 116
+TSSG +S H A ++GE S H ++ G G+ S
Sbjct: 2956 QTSSGGQ----------AASSHEQARSSAGERHGSHHQQSADSSRHSGIGH---GQASSA 3002
Query: 117 EQPSGEHLSGEQPLSELESGEQPSDEQPSGEHG-SGEQPSGEQASGEQPSG 166
+ SG S+ E + SD Q HG +G Q S SG
Sbjct: 3003 VRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSG 3053
Score = 28.9 bits (63), Expect = 4.3
Identities = 37/166 (22%), Positives = 59/166 (35%), Gaps = 17/166 (10%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSS-----GLNTLSEHG 69
S+R + S E +GS + + + S P D+E E++S S G
Sbjct: 3839 SSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDG 3898
Query: 70 SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHA-------EGEHTVGEQPSGEQPSGE 122
S GSS A H +S+ ++ A EH + + G Q G S
Sbjct: 3899 SRHPGSSHRDTASHVQSSPVQSDSST----AKEHGHFSSLSQDSAYHSGIQSRGSPHSSS 3954
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTI 168
+ +E + G Q G +GS + GE G++
Sbjct: 3955 SYHYQSEGTERQKG-QSGLVWRHGSYGSADYDYGESGFRHSQHGSV 3999
Score = 28.5 bits (62), Expect = 5.6
Identities = 29/134 (21%), Positives = 46/134 (34%), Gaps = 3/134 (2%)
Query: 21 SQPNELSGSIDHQTSVQQLPGEFFSLENPSDA--EALYETSSGLNTLSEHGSSEHGSSKH 78
S P E GS HQ S S A ++ + SSG + G SE ++
Sbjct: 1351 SSPGERHGS-RHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQS 1409
Query: 79 TVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQ 138
A +G H +S S + E + + Q S + S P + G +
Sbjct: 1410 VSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSR 1469
Query: 139 PSDEQPSGEHGSGE 152
+ S H + +
Sbjct: 1470 HEQARNSSRHSASQ 1483
Score = 28.5 bits (62), Expect = 5.6
Identities = 47/190 (24%), Positives = 71/190 (37%), Gaps = 44/190 (23%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEF----------FSLENPSDAEALYETS---SG 61
S+R + S+ +E S D Q + G+ S+ SD+E E S SG
Sbjct: 3174 SSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSG 3233
Query: 62 LNTLSEHGS----SEHGSSKHTVAEHTS----GEHAE---------SEHASGEPAATEHA 104
+ + GS S HGS +H + H G A+ +E +SG AA+ H
Sbjct: 3234 SASRNHRGSVQEQSRHGS-RHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHE 3292
Query: 105 EGEHTVGE------QPSGEQPSGEHLSGEQPLSEL-------ESGEQPSDEQPSGEHGSG 151
+ + GE Q S + + Q S + SG Q SD + E
Sbjct: 3293 QARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDT 3352
Query: 152 EQPSGEQASG 161
+ SG +G
Sbjct: 3353 QSVSGHGQAG 3362
Score = 28.5 bits (62), Expect = 5.6
Identities = 26/136 (19%), Positives = 40/136 (29%), Gaps = 3/136 (2%)
Query: 27 SGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSG 86
S S H+ S Q A + G + + S H + S
Sbjct: 3502 SWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASR 3561
Query: 87 EH---AESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQ 143
H A+ + G T H E G + SG H + + S + +
Sbjct: 3562 NHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSS 3621
Query: 144 PSGEHGSGEQPSGEQA 159
HGS Q S + +
Sbjct: 3622 AGERHGSHHQQSADSS 3637
Score = 28.1 bits (61), Expect = 7.3
Identities = 19/102 (18%), Positives = 34/102 (33%), Gaps = 7/102 (6%)
Query: 66 SEHGSSEH-------GSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQ 118
S H S H GSS+H+ +++ G + + H+ + E
Sbjct: 1554 SRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSES 1613
Query: 119 PSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQAS 160
S H + S S S ++ HG + S + +
Sbjct: 1614 ASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGT 1655
Score = 28.1 bits (61), Expect = 7.3
Identities = 28/134 (20%), Positives = 45/134 (33%), Gaps = 20/134 (14%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESE--------HASGEP 98
E S +A ++ E S H S + + +G +S +SG
Sbjct: 1659 ETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQ 1718
Query: 99 AATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQ-----------PSDEQPSGE 147
A+ E + + S +G H Q + +SGE+ + EQ
Sbjct: 1719 ASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESA 1778
Query: 148 HG-SGEQPSGEQAS 160
HG +G G Q S
Sbjct: 1779 HGRTGPSTGGRQRS 1792
Score = 27.7 bits (60), Expect = 9.5
Identities = 30/140 (21%), Positives = 49/140 (35%), Gaps = 11/140 (7%)
Query: 15 SARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHG 74
SARG S + + SGS +Q S + PS S H +S+ G
Sbjct: 2075 SARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEG 2134
Query: 75 SSKHTVAEH----TSGEHAESEHASGEPAATEHAEGEHTV--GEQPSGEQPSGEHLSGEQ 128
+ T+ H G + S + + + HT G + SG + +
Sbjct: 2135 --QDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRK 2192
Query: 129 PLSELESGEQPSDEQPSGEH 148
+ +SG+ + SG H
Sbjct: 2193 TYDKEQSGD---GSRHSGSH 2209
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTS----GEHAESEHASGEPAATEHAE 105
S+A + TSS T S GS E + TV+E T+ G A + A+G A T E
Sbjct: 1121 SEATTVSTTSSETTTASTTGS-EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G T +G + + +G + + +G + + SG + +G + S +
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239
Query: 166 GTILN 170
G+ N
Sbjct: 1240 GSETN 1244
Score = 32.0 bits (71), Expect = 0.51
Identities = 28/154 (18%), Positives = 55/154 (35%), Gaps = 5/154 (3%)
Query: 19 TSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG--LNTLSEHGSSEHGSS 76
T S + +I +T+ G + + +E ++ G + T+S GS +S
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 77 ---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
T T G + +G T AEG T G + + +G + +
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS 987
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGT 167
+G + + G + +G + + +GT
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021
Score = 27.7 bits (60), Expect = 9.5
Identities = 21/121 (17%), Positives = 41/121 (33%), Gaps = 3/121 (2%)
Query: 50 SDAEALYETSSGLNTLSEHG---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + Y T S T S G ++ T T G + A+G T EG
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G + + +G + + G + + +G + + G + +G
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590
Query: 167 T 167
+
Sbjct: 591 S 591
>gi|239746922 PREDICTED: similar to cancer/testis antigen family
147, member B1 isoform 2 [Homo sapiens]
Length = 294
Score = 40.0 bits (92), Expect = 0.002
Identities = 21/60 (35%), Positives = 38/60 (63%), Gaps = 3/60 (5%)
Query: 104 AEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQ 163
AE E+P+ E+P+ E + E+ L+E E+ E+P+ E+P+ E S E+P+ E+A+ +
Sbjct: 198 AEMAREPAEEPAEEKPTEE--AAEEELAE-EAAEEPAKEEPAAEEESAEEPATEEAAAPE 254
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTS----GEHAESEHASGEPAATEHAE 105
S+A + TSS T S GS E + TV+E T+ G A + A+G A T E
Sbjct: 1121 SEATTVSTTSSETTTASTTGS-EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G T +G + + +G + + +G + + SG + +G + S +
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239
Query: 166 GTILN 170
G+ N
Sbjct: 1240 GSETN 1244
Score = 32.0 bits (71), Expect = 0.51
Identities = 28/154 (18%), Positives = 55/154 (35%), Gaps = 5/154 (3%)
Query: 19 TSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG--LNTLSEHGSSEHGSS 76
T S + +I +T+ G + + +E ++ G + T+S GS +S
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 77 ---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
T T G + +G T AEG T G + + +G + +
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS 987
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGT 167
+G + + G + +G + + +GT
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021
Score = 27.7 bits (60), Expect = 9.5
Identities = 21/121 (17%), Positives = 41/121 (33%), Gaps = 3/121 (2%)
Query: 50 SDAEALYETSSGLNTLSEHG---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + Y T S T S G ++ T T G + A+G T EG
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G + + +G + + G + + +G + + G + +G
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590
Query: 167 T 167
+
Sbjct: 591 S 591
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTS----GEHAESEHASGEPAATEHAE 105
S+A + TSS T S GS E + TV+E T+ G A + A+G A T E
Sbjct: 1121 SEATTVSTTSSETTTASTTGS-EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G T +G + + +G + + +G + + SG + +G + S +
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239
Query: 166 GTILN 170
G+ N
Sbjct: 1240 GSETN 1244
Score = 32.0 bits (71), Expect = 0.51
Identities = 28/154 (18%), Positives = 55/154 (35%), Gaps = 5/154 (3%)
Query: 19 TSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG--LNTLSEHGSSEHGSS 76
T S + +I +T+ G + + +E ++ G + T+S GS +S
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 77 ---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
T T G + +G T AEG T G + + +G + +
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS 987
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGT 167
+G + + G + +G + + +GT
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021
Score = 27.7 bits (60), Expect = 9.5
Identities = 21/121 (17%), Positives = 41/121 (33%), Gaps = 3/121 (2%)
Query: 50 SDAEALYETSSGLNTLSEHG---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + Y T S T S G ++ T T G + A+G T EG
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G + + +G + + G + + +G + + G + +G
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590
Query: 167 T 167
+
Sbjct: 591 S 591
>gi|49087132 sal-like 2 [Homo sapiens]
Length = 1007
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/162 (25%), Positives = 62/162 (38%), Gaps = 6/162 (3%)
Query: 14 GSARGTSSQPNELSG--SIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSS 71
G+A+ S+ + +SG S Q S Q P E S E + E E + ++L+ GS
Sbjct: 730 GAAQENGSEQSTVSGAGSFPQQQSQQPSPEEELSEEEEEEDEEEEEDVTDEDSLAGRGSE 789
Query: 72 EHGSSKHTV---AEHTSGEHAE-SEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGE 127
G +V +E SG E A+ A E E T + P + L
Sbjct: 790 SGGEKAISVRGDSEEASGAEEEVGTVAAAATAGKEMDSNEKTTQQSSLPPPPPPDSLDQP 849
Query: 128 QPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGTIL 169
QP+ + SG E+ S S GE S T++
Sbjct: 850 QPMEQGSSGVLGGKEEGGKPERSSSPASALTPEGEATSVTLV 891
>gi|33286446 opioid growth factor receptor [Homo sapiens]
Length = 677
Score = 39.7 bits (91), Expect = 0.002
Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 20/133 (15%)
Query: 47 ENPSDAEALYETSSGLNTLSEHGS---SEH---GSSKHTVAEHTSGEHAESEHASGEPAA 100
E D+ A+ S G TL+ GS S H G S++ V E T G E G P+
Sbjct: 463 EGAGDSAAV--ASGGAQTLALAGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSE 520
Query: 101 TEHAEGEHTVGEQPS-------GEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQ 153
T G++P+ G +P+G +G++P ES + +P+G G
Sbjct: 521 TPGPSPAGPAGDEPAESPSETPGPRPAGP--AGDEP---AESPSETPGPRPAGPAGDEPA 575
Query: 154 PSGEQASGEQPSG 166
S + G P+G
Sbjct: 576 ESPSETPGPSPAG 588
>gi|30794264 glycosylphosphatidylinositol anchored high density
lipoprotein binding protein 1 [Homo sapiens]
Length = 184
Score = 39.7 bits (91), Expect = 0.002
Identities = 27/117 (23%), Positives = 44/117 (37%), Gaps = 4/117 (3%)
Query: 131 SELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG---TILNCYTCAYMNDQGKCLRGE 187
++ E E+ D P E E+ + P G +L CYTC + +C +
Sbjct: 22 TQQEEEEEDEDHGPDDYDEEDEDEVEEEETNRLPGGRSRVLLRCYTCKSLPRDERCNLTQ 81
Query: 188 GTCITQNSQQCMLKKIFEGGKLQFMVQGCENMCPSMNLFSHGTRMQIICCRNQSFCN 244
Q + E G L C + C + GT++ + CC++ S CN
Sbjct: 82 NCSHGQTCTTLIAHGNTESGLLTTHSTWCTDSCQPITKTVEGTQVTMTCCQS-SLCN 137
>gi|126090892 aggrecan isoform 2 precursor [Homo sapiens]
Length = 2416
Score = 38.9 bits (89), Expect = 0.004
Identities = 45/175 (25%), Positives = 65/175 (37%), Gaps = 25/175 (14%)
Query: 5 LLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT 64
+L S +G G S L S+ + LP E + ++SG+
Sbjct: 1342 VLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPS----------GEVVETSASGIED 1391
Query: 65 LSEHGSSE----HGSSKHTVAEHTSGEHAESEHASG-----------EPAATEHAEGEHT 109
+SE S E S ++ SGE ASG E T +E
Sbjct: 1392 VSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTD 1451
Query: 110 VGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQP 164
+ PSG + SG + LS L SG++ SG+ G+ PSG SG+ P
Sbjct: 1452 LSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAP 1506
Score = 35.0 bits (79), Expect = 0.060
Identities = 38/122 (31%), Positives = 49/122 (40%), Gaps = 16/122 (13%)
Query: 61 GLNTLSEHGSSEHG---SSKHTVAEHTSGEHAESE---HASGEPAATEHAEGEHTVGEQP 114
G T+ G+ E SS+ ++ SG + +E ASG P + G V QP
Sbjct: 1566 GRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQP 1625
Query: 115 SGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG-EQASGE---------QP 164
SG + SG LS L SG+ + SG QP G SGE QP
Sbjct: 1626 SGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQP 1685
Query: 165 SG 166
SG
Sbjct: 1686 SG 1687
Score = 34.3 bits (77), Expect = 0.10
Identities = 43/164 (26%), Positives = 57/164 (34%), Gaps = 12/164 (7%)
Query: 13 LGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENP----SDAEALYETSSGLNTLSEH 68
L G + SG++D Q P EF L + S + E S L + + +
Sbjct: 1751 LSGKSGMVDVSGQFSGTVDSSGFTSQTP-EFSGLPSGIAEVSGESSRAEIGSSLPSGAYY 1809
Query: 69 GSSEHGSSK------HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
GS S T+ E + E G P+ G H+ SGE
Sbjct: 1810 GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEG-PSGILELSGAHSGAPDMSGEHSGFL 1868
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
LSG Q SGE P SG+ S SGE + SG
Sbjct: 1869 DLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSG 1912
Score = 33.5 bits (75), Expect = 0.17
Identities = 44/151 (29%), Positives = 55/151 (36%), Gaps = 38/151 (25%)
Query: 49 PSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEH 108
PS E L + SG+ +S S E V SG SE SGE T A G
Sbjct: 1357 PSGGEVLEISVSGVEDISGLPSGE------VVETSASGIEDVSELPSGEGLETS-ASGVE 1409
Query: 109 TVGEQPSGEQ---------------PSG-EHL---------------SGEQPLSELESGE 137
+ PSGE+ PSG E L SG + L SG
Sbjct: 1410 DLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGA 1469
Query: 138 QPSDEQPSGEHGSGEQPSGEQASGEQPSGTI 168
+ PSG+ SG+ G+ PSGT+
Sbjct: 1470 EDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500
Score = 31.2 bits (69), Expect = 0.86
Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 12/160 (7%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSK 77
GT+S E SG TS+ ++ F E + L SG LS S +
Sbjct: 1704 GTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQ 1763
Query: 78 HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLS------ 131
+ +SG +++ SG P+ GE + E S PSG + P S
Sbjct: 1764 FSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGS-SLPSGAYYGSGTPSSFPTVSL 1822
Query: 132 ----ELESGEQPSDEQPSGEHGSG-EQPSGEQASGEQPSG 166
+ES Q Q +GE SG + SG + SG
Sbjct: 1823 VDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSG 1862
Score = 31.2 bits (69), Expect = 0.86
Identities = 36/138 (26%), Positives = 50/138 (36%), Gaps = 14/138 (10%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLP-GEFFSLENPSDA-------EALYETSSGLNTLSEHG 69
G S E+SG LP G ++ PS L E+ + T E G
Sbjct: 1782 GLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAG 1841
Query: 70 SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQP 129
G + SG H+ + SGE + G + +PSGE P + SG+
Sbjct: 1842 EGPSGILE------LSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFA 1895
Query: 130 LSELESGEQPSDEQPSGE 147
+ SGE SGE
Sbjct: 1896 STTNVSGESSVAMGTSGE 1913
Score = 30.8 bits (68), Expect = 1.1
Identities = 34/94 (36%), Positives = 37/94 (39%), Gaps = 11/94 (11%)
Query: 85 SGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQ- 143
SG ES SG+ E TVGE PSG + SG LS L SGE
Sbjct: 910 SGLPVESGLPSGDEERIEWPSTP-TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSAS 968
Query: 144 --------PSGEHGSGEQPSGEQASGEQPSGTIL 169
PSGE P E SG PSG +L
Sbjct: 969 GVGDLSGLPSGEVLETTAPGVEDISG-LPSGEVL 1001
Score = 28.5 bits (62), Expect = 5.6
Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 4/86 (4%)
Query: 84 TSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSG---EHLSGEQPLSELESGEQPS 140
+SGE + + SG+ + G Q SG++ SG L S + SG
Sbjct: 856 SSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVE 915
Query: 141 DEQPSGEHGSGEQPSGEQASGEQPSG 166
PSG+ E PS GE PSG
Sbjct: 916 SGLPSGDEERIEWPS-TPTVGELPSG 940
Score = 28.1 bits (61), Expect = 7.3
Identities = 45/150 (30%), Positives = 57/150 (38%), Gaps = 11/150 (7%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLEN----PSDAEALYETSSGLNTLS--EHGSS 71
G +SQ E SG + + ++ GE E PS A T S T+S +
Sbjct: 1772 GFTSQTPEFSGL---PSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLV 1828
Query: 72 EHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLS 131
E + T E G E SG + GEH+ SG Q SGE P +
Sbjct: 1829 ESVTQAPTAQEAGEGPSGILE-LSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGT 1887
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASG 161
SG+ S SGE SGE ASG
Sbjct: 1888 PYFSGDFASTTNVSGESSVAMGTSGE-ASG 1916
>gi|126090883 aggrecan isoform 1 precursor [Homo sapiens]
Length = 2317
Score = 38.9 bits (89), Expect = 0.004
Identities = 45/175 (25%), Positives = 65/175 (37%), Gaps = 25/175 (14%)
Query: 5 LLLMSLYLLGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNT 64
+L S +G G S L S+ + LP E + ++SG+
Sbjct: 1342 VLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPS----------GEVVETSASGIED 1391
Query: 65 LSEHGSSE----HGSSKHTVAEHTSGEHAESEHASG-----------EPAATEHAEGEHT 109
+SE S E S ++ SGE ASG E T +E
Sbjct: 1392 VSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTD 1451
Query: 110 VGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQP 164
+ PSG + SG + LS L SG++ SG+ G+ PSG SG+ P
Sbjct: 1452 LSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAP 1506
Score = 35.0 bits (79), Expect = 0.060
Identities = 38/122 (31%), Positives = 49/122 (40%), Gaps = 16/122 (13%)
Query: 61 GLNTLSEHGSSEHG---SSKHTVAEHTSGEHAESE---HASGEPAATEHAEGEHTVGEQP 114
G T+ G+ E SS+ ++ SG + +E ASG P + G V QP
Sbjct: 1566 GRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQP 1625
Query: 115 SGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSG-EQASGE---------QP 164
SG + SG LS L SG+ + SG QP G SGE QP
Sbjct: 1626 SGFPDTSGETSGVTELSGLSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQP 1685
Query: 165 SG 166
SG
Sbjct: 1686 SG 1687
Score = 34.3 bits (77), Expect = 0.10
Identities = 43/164 (26%), Positives = 57/164 (34%), Gaps = 12/164 (7%)
Query: 13 LGSARGTSSQPNELSGSIDHQTSVQQLPGEFFSLENP----SDAEALYETSSGLNTLSEH 68
L G + SG++D Q P EF L + S + E S L + + +
Sbjct: 1751 LSGKSGMVDVSGQFSGTVDSSGFTSQTP-EFSGLPSGIAEVSGESSRAEIGSSLPSGAYY 1809
Query: 69 GSSEHGSSK------HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGE 122
GS S T+ E + E G P+ G H+ SGE
Sbjct: 1810 GSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEG-PSGILELSGAHSGAPDMSGEHSGFL 1868
Query: 123 HLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
LSG Q SGE P SG+ S SGE + SG
Sbjct: 1869 DLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSG 1912
Score = 33.5 bits (75), Expect = 0.17
Identities = 44/151 (29%), Positives = 55/151 (36%), Gaps = 38/151 (25%)
Query: 49 PSDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEH 108
PS E L + SG+ +S S E V SG SE SGE T A G
Sbjct: 1357 PSGGEVLEISVSGVEDISGLPSGE------VVETSASGIEDVSELPSGEGLETS-ASGVE 1409
Query: 109 TVGEQPSGEQ---------------PSG-EHL---------------SGEQPLSELESGE 137
+ PSGE+ PSG E L SG + L SG
Sbjct: 1410 DLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGA 1469
Query: 138 QPSDEQPSGEHGSGEQPSGEQASGEQPSGTI 168
+ PSG+ SG+ G+ PSGT+
Sbjct: 1470 EDLSGLPSGKEDLVGSASGDLDLGKLPSGTL 1500
Score = 31.2 bits (69), Expect = 0.86
Identities = 42/160 (26%), Positives = 60/160 (37%), Gaps = 12/160 (7%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSGLNTLSEHGSSEHGSSK 77
GT+S E SG TS+ ++ F E + L SG LS S +
Sbjct: 1704 GTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQ 1763
Query: 78 HTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLS------ 131
+ +SG +++ SG P+ GE + E S PSG + P S
Sbjct: 1764 FSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGS-SLPSGAYYGSGTPSSFPTVSL 1822
Query: 132 ----ELESGEQPSDEQPSGEHGSG-EQPSGEQASGEQPSG 166
+ES Q Q +GE SG + SG + SG
Sbjct: 1823 VDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSG 1862
Score = 31.2 bits (69), Expect = 0.86
Identities = 36/138 (26%), Positives = 50/138 (36%), Gaps = 14/138 (10%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLP-GEFFSLENPSDA-------EALYETSSGLNTLSEHG 69
G S E+SG LP G ++ PS L E+ + T E G
Sbjct: 1782 GLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAG 1841
Query: 70 SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQP 129
G + SG H+ + SGE + G + +PSGE P + SG+
Sbjct: 1842 EGPSGILE------LSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFA 1895
Query: 130 LSELESGEQPSDEQPSGE 147
+ SGE SGE
Sbjct: 1896 STTNVSGESSVAMGTSGE 1913
Score = 30.8 bits (68), Expect = 1.1
Identities = 34/94 (36%), Positives = 37/94 (39%), Gaps = 11/94 (11%)
Query: 85 SGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQ- 143
SG ES SG+ E TVGE PSG + SG LS L SGE
Sbjct: 910 SGLPVESGLPSGDEERIEWPSTP-TVGELPSGAEILEGSASGVGDLSGLPSGEVLETSAS 968
Query: 144 --------PSGEHGSGEQPSGEQASGEQPSGTIL 169
PSGE P E SG PSG +L
Sbjct: 969 GVGDLSGLPSGEVLETTAPGVEDISG-LPSGEVL 1001
Score = 28.5 bits (62), Expect = 5.6
Identities = 26/86 (30%), Positives = 35/86 (40%), Gaps = 4/86 (4%)
Query: 84 TSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSG---EHLSGEQPLSELESGEQPS 140
+SGE + + SG+ + G Q SG++ SG L S + SG
Sbjct: 856 SSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVE 915
Query: 141 DEQPSGEHGSGEQPSGEQASGEQPSG 166
PSG+ E PS GE PSG
Sbjct: 916 SGLPSGDEERIEWPS-TPTVGELPSG 940
Score = 28.1 bits (61), Expect = 7.3
Identities = 45/150 (30%), Positives = 57/150 (38%), Gaps = 11/150 (7%)
Query: 18 GTSSQPNELSGSIDHQTSVQQLPGEFFSLEN----PSDAEALYETSSGLNTLS--EHGSS 71
G +SQ E SG + + ++ GE E PS A T S T+S +
Sbjct: 1772 GFTSQTPEFSGL---PSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLV 1828
Query: 72 EHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLS 131
E + T E G E SG + GEH+ SG Q SGE P +
Sbjct: 1829 ESVTQAPTAQEAGEGPSGILE-LSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGT 1887
Query: 132 ELESGEQPSDEQPSGEHGSGEQPSGEQASG 161
SG+ S SGE SGE ASG
Sbjct: 1888 PYFSGDFASTTNVSGESSVAMGTSGE-ASG 1916
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 38.1 bits (87), Expect = 0.007
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 5/144 (3%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTS----GEHAESEHASGEPAATEHAE 105
S+A + TSS T S GS E + TV+E T+ G A + A+G A T E
Sbjct: 1121 SEATTVSTTSSETTTASTTGS-EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G T +G + + +G + + SG + + +G S +G + +
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1239
Query: 166 GTILNCYTCAYMNDQGKCLRGEGT 189
G+ + A + L G T
Sbjct: 1240 GSETTIASTASLEPTATSLTGSET 1263
Score = 32.0 bits (71), Expect = 0.51
Identities = 28/154 (18%), Positives = 55/154 (35%), Gaps = 5/154 (3%)
Query: 19 TSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG--LNTLSEHGSSEHGSS 76
T S + +I +T+ G + + +E ++ G + T+S GS +S
Sbjct: 868 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 927
Query: 77 ---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
T T G + +G T AEG T G + + +G + +
Sbjct: 928 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS 987
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGT 167
+G + + G + +G + + +GT
Sbjct: 988 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1021
Score = 27.7 bits (60), Expect = 9.5
Identities = 21/121 (17%), Positives = 41/121 (33%), Gaps = 3/121 (2%)
Query: 50 SDAEALYETSSGLNTLSEHG---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + Y T S T S G ++ T T G + A+G T EG
Sbjct: 471 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G + + +G + + G + + +G + + G + +G
Sbjct: 531 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590
Query: 167 T 167
+
Sbjct: 591 S 591
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 38.1 bits (87), Expect = 0.007
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 5/144 (3%)
Query: 50 SDAEALYETSSGLNTLSEHGSSEHGSSKHTVAEHTS----GEHAESEHASGEPAATEHAE 105
S+A + TSS T S GS E + TV+E T+ G A + A+G A T E
Sbjct: 1142 SEATTVSTTSSETTTASTTGS-EMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1200
Query: 106 GEHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPS 165
G T +G + + +G + + SG + + +G S +G + +
Sbjct: 1201 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1260
Query: 166 GTILNCYTCAYMNDQGKCLRGEGT 189
G+ + A + L G T
Sbjct: 1261 GSETTIASTASLEPTATSLTGSET 1284
Score = 32.0 bits (71), Expect = 0.51
Identities = 28/154 (18%), Positives = 55/154 (35%), Gaps = 5/154 (3%)
Query: 19 TSSQPNELSGSIDHQTSVQQLPGEFFSLENPSDAEALYETSSG--LNTLSEHGSSEHGSS 76
T S + +I +T+ G + + +E ++ G + T+S GS +S
Sbjct: 889 TESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTAS 948
Query: 77 ---KHTVAEHTSGEHAESEHASGEPAATEHAEGEHTVGEQPSGEQPSGEHLSGEQPLSEL 133
T T G + +G T AEG T G + + +G + +
Sbjct: 949 TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVS 1008
Query: 134 ESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSGT 167
+G + + G + +G + + +GT
Sbjct: 1009 TAGSETTTASIEGSETTTVSSTGSETTTVSTTGT 1042
Score = 27.7 bits (60), Expect = 9.5
Identities = 21/121 (17%), Positives = 41/121 (33%), Gaps = 3/121 (2%)
Query: 50 SDAEALYETSSGLNTLSEHG---SSEHGSSKHTVAEHTSGEHAESEHASGEPAATEHAEG 106
S+ + Y T S T S G ++ T T G + A+G T EG
Sbjct: 492 SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 551
Query: 107 EHTVGEQPSGEQPSGEHLSGEQPLSELESGEQPSDEQPSGEHGSGEQPSGEQASGEQPSG 166
+G + + +G + + G + + +G + + G + +G
Sbjct: 552 SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 611
Query: 167 T 167
+
Sbjct: 612 S 612
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.126 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,065,764
Number of Sequences: 37866
Number of extensions: 618195
Number of successful extensions: 4143
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 235
Number of HSP's that attempted gapping in prelim test: 2835
Number of HSP's gapped (non-prelim): 1042
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.