Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 9910596
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]
(390 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9910596 tuftelin 1 isoform 1 [Homo sapiens] 762 0.0
gi|187607364 tuftelin 1 isoform 2 [Homo sapiens] 701 0.0
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 112 4e-25
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 112 4e-25
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 112 4e-25
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 80 4e-15
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 71 1e-12
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 71 1e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 65 1e-10
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 62 7e-10
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 62 7e-10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 62 9e-10
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 62 1e-09
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 62 1e-09
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 61 2e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 60 3e-09
gi|116812628 coiled-coil domain containing 67 [Homo sapiens] 60 3e-09
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 60 3e-09
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 59 6e-09
gi|4503593 epidermal growth factor receptor pathway substrate 15... 59 7e-09
gi|55770834 centromere protein F [Homo sapiens] 59 7e-09
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 59 7e-09
gi|38044112 restin isoform b [Homo sapiens] 58 1e-08
gi|4506751 restin isoform a [Homo sapiens] 58 1e-08
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 58 2e-08
gi|4504063 golgin 97 [Homo sapiens] 58 2e-08
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 57 2e-08
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 57 2e-08
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 57 2e-08
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 57 2e-08
>gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]
Length = 390
Score = 762 bits (1967), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MNGTRNWCTLVDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAG 60
MNGTRNWCTLVDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAG
Sbjct: 1 MNGTRNWCTLVDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAG 60
Query: 61 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 120
HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI
Sbjct: 61 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 120
Query: 121 SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL 180
SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL
Sbjct: 121 SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL 180
Query: 181 AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME 240
AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME
Sbjct: 181 AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME 240
Query: 241 TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR 300
TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR
Sbjct: 241 TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR 300
Query: 301 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ 360
KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ
Sbjct: 301 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ 360
Query: 361 ARAKTENPGSIRISKPPSPKPMPVIRVVET 390
ARAKTENPGSIRISKPPSPKPMPVIRVVET
Sbjct: 361 ARAKTENPGSIRISKPPSPKPMPVIRVVET 390
>gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]
Length = 365
Score = 701 bits (1808), Expect = 0.0
Identities = 365/390 (93%), Positives = 365/390 (93%), Gaps = 25/390 (6%)
Query: 1 MNGTRNWCTLVDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAG 60
MNGTRNWCTLVDVHPEDQAA AGRKTYAMVSSHSAG
Sbjct: 1 MNGTRNWCTLVDVHPEDQAA-------------------------AGRKTYAMVSSHSAG 35
Query: 61 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 120
HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI
Sbjct: 36 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 95
Query: 121 SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL 180
SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL
Sbjct: 96 SSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL 155
Query: 181 AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME 240
AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME
Sbjct: 156 AKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME 215
Query: 241 TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR 300
TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR
Sbjct: 216 TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR 275
Query: 301 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ 360
KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ
Sbjct: 276 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQ 335
Query: 361 ARAKTENPGSIRISKPPSPKPMPVIRVVET 390
ARAKTENPGSIRISKPPSPKPMPVIRVVET
Sbjct: 336 ARAKTENPGSIRISKPPSPKPMPVIRVVET 365
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 112 bits (281), Expect = 4e-25
Identities = 64/182 (35%), Positives = 105/182 (57%), Gaps = 5/182 (2%)
Query: 170 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 229
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
Query: 230 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 289
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
Query: 290 HLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 349
HLDDM+ QQ+KV+QM+E++++ K +Q K I +L EKI++LE EN E+ R+++L E
Sbjct: 355 HLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTE 414
Query: 350 KQ 351
Q
Sbjct: 415 TQ 416
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 112 bits (281), Expect = 4e-25
Identities = 64/182 (35%), Positives = 105/182 (57%), Gaps = 5/182 (2%)
Query: 170 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 229
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
Query: 230 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 289
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
Query: 290 HLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 349
HLDDM+ QQ+KV+QM+E++++ K +Q K I +L EKI++LE EN E+ R+++L E
Sbjct: 355 HLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTE 414
Query: 350 KQ 351
Q
Sbjct: 415 TQ 416
Score = 37.0 bits (84), Expect = 0.031
Identities = 58/294 (19%), Positives = 125/294 (42%), Gaps = 29/294 (9%)
Query: 55 SSHSAGHSLASELVES-HDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCL 113
SS A + E+ + + +EE ++ + S +K E + + S ++ I+EA +
Sbjct: 229 SSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK---EALLEETNSFLKAIEEANKKM 285
Query: 114 QKLREDISSKLDRNLGD------SLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINE 167
Q + K D+ +G+ + ++ Q+ L+ ++ L S E + E
Sbjct: 286 QAAEISLEEK-DQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEE 344
Query: 168 DVESLRKTVQDL--LAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK 225
SLR+ ++ L + Q+ K + + + +++ +Q + + + +++
Sbjct: 345 ASASLRERIRHLDDMVHCQQKKVKQMVE------EIESLKKKLQQKQLLILQLLEKISFL 398
Query: 226 EAEVGELQRRLLGMETEHQALLAKVREGEVALEEL-----RSNNADCQAEREKAATLEKE 280
E E ELQ RL + + RE V + L R N++ ++ + + E
Sbjct: 399 EGENNELQSRLDYLTETQAKTEVETREIGVGCDLLPRLPFRQNDSSSHCQKS-GSPISSE 457
Query: 281 VAGLREKIHHLDDMLKSQQRKVRQMIEQL---QNSKAVIQSKDATIQELKEKIA 331
R+K HLDD+ ++ + M QL + S A+ + + +E++ K+A
Sbjct: 458 ERRRRDK-QHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLA 510
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 112 bits (281), Expect = 4e-25
Identities = 64/182 (35%), Positives = 105/182 (57%), Gaps = 5/182 (2%)
Query: 170 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 229
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
Query: 230 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 289
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
Query: 290 HLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 349
HLDDM+ QQ+KV+QM+E++++ K +Q K I +L EKI++LE EN E+ R+++L E
Sbjct: 355 HLDDMVHCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTE 414
Query: 350 KQ 351
Q
Sbjct: 415 TQ 416
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 79.7 bits (195), Expect = 4e-15
Identities = 47/139 (33%), Positives = 77/139 (55%), Gaps = 5/139 (3%)
Query: 170 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 229
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
Query: 230 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 289
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
Query: 290 HLDDMLKSQQRKVRQMIEQ 308
HLDDM+ QQ+KV+QM+E+
Sbjct: 355 HLDDMVHCQQKKVKQMVEE 373
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 71.2 bits (173), Expect = 1e-12
Identities = 61/281 (21%), Positives = 129/281 (45%), Gaps = 38/281 (13%)
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLR----------EDISSKLDRNLGDSLHRQE---- 136
++E + E +Y+++ R LQK+R + + KLD +L +
Sbjct: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEM 81
Query: 137 ------IQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVES----LRKTVQDLLAKLQ-- 184
+ ++++K G + + + E+ LR Q L Q
Sbjct: 82 DPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQ 141
Query: 185 --EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 242
E +++ + +V +++ +Q L + +++E+K +++ EL+ + ME E
Sbjct: 142 SEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKE 201
Query: 243 HQALLAKVREGEVALEELRSN---NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ 299
+ LL + E L +L+S+ CQ L++E++ L+E+I HL ++ SQ
Sbjct: 202 KRTLLERKLSLENKLLQLKSSATYGKSCQ-------DLQREISILQEQISHLQFVIHSQH 254
Query: 300 RKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 340
+ +R +I++++ K ++ +D I+ L+EK+ LEA+N E+
Sbjct: 255 QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL 295
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 71.2 bits (173), Expect = 1e-12
Identities = 61/281 (21%), Positives = 129/281 (45%), Gaps = 38/281 (13%)
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLR----------EDISSKLDRNLGDSLHRQE---- 136
++E + E +Y+++ R LQK+R + + KLD +L +
Sbjct: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGNLQQGSDSEM 81
Query: 137 ------IQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVES----LRKTVQDLLAKLQ-- 184
+ ++++K G + + + E+ LR Q L Q
Sbjct: 82 DPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQ 141
Query: 185 --EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 242
E +++ + +V +++ +Q L + +++E+K +++ EL+ + ME E
Sbjct: 142 SEEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKE 201
Query: 243 HQALLAKVREGEVALEELRSN---NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ 299
+ LL + E L +L+S+ CQ L++E++ L+E+I HL ++ SQ
Sbjct: 202 KRTLLERKLSLENKLLQLKSSATYGKSCQ-------DLQREISILQEQISHLQFVIHSQH 254
Query: 300 RKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 340
+ +R +I++++ K ++ +D I+ L+EK+ LEA+N E+
Sbjct: 255 QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKEL 295
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 64.7 bits (156), Expect = 1e-10
Identities = 51/268 (19%), Positives = 122/268 (45%), Gaps = 17/268 (6%)
Query: 96 INQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPNGFSQSPTA 153
+NQ + E + QE + +Q+ E I + + R + + RQE +++ EK +
Sbjct: 282 LNQQQEEKMWRQEEK--IQEREEKIQEQEEKIREQEEKMRRQE-EMMWEKEEKMRRQEEM 338
Query: 154 LYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNV 213
++ ++ + E + K + + +E K + Q E + R + + +
Sbjct: 339 MWEKEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 214 ALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVAL-----------EELRS 262
++ +E+ ++++E ++GE + ++ E E Q K+R E + E++R
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 263 NNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDAT 322
Q + EK E ++ K+ ++ ++ Q+ K+R+ ++++ + I+ ++
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517
Query: 323 IQELKEKIAYLEAENLEMHDRMEHLIEK 350
+QE +EK+ E + E ++M+ EK
Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Score = 60.5 bits (145), Expect = 3e-09
Identities = 55/273 (20%), Positives = 124/273 (45%), Gaps = 24/273 (8%)
Query: 95 NINQLKSEV---------QYIQEARNCLQKLREDISSKL-----DRNLGDSLHRQEIQVV 140
N+ +LK ++ Q +Q + L K + +S+KL + L + L++Q+ + +
Sbjct: 231 NVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM 290
Query: 141 LEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVT 200
+ + + E + I E E +R+ + + K ++ +RQ + E
Sbjct: 291 WRQEEKIQEREEKIQ----EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 201 LSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLA---KVREGEVAL 257
++ EQ + Q E+ + E+K E + Q + M + + + K+RE E +
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM 406
Query: 258 EELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQ 317
+E + + EK E+E+ EK+ ++ ++ Q++K+R+ E+++ + ++Q
Sbjct: 407 QEQEEKMGE---QEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 463
Query: 318 SKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 350
++ + E + K+ EA+ E ++M EK
Sbjct: 464 EQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEK 496
Score = 54.3 bits (129), Expect = 2e-07
Identities = 53/275 (19%), Positives = 127/275 (46%), Gaps = 19/275 (6%)
Query: 75 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 134
E+I + K R ++M+ EK +++ + + + E +++L E + + ++ R
Sbjct: 309 EKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKIRELEEKMHEQ-EKIREQEEKR 366
Query: 135 QEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC 194
QE + + E+ Q I E E +R+ Q+ + + QE K Q
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEK-----IREQEEKIRE--QEEMMQEQEEKMGEQ--- 416
Query: 195 VAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKV--RE 252
E + + E ++ ++R+E+++ ++E ++ E + ++ E Q K+ +E
Sbjct: 417 ---EEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQE 473
Query: 253 GEVALEELRSNNADCQAER--EKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQ 310
G++ +E + + + R EK EK++ EKI ++M++ Q+ K+ + E++
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMC 533
Query: 311 NSKAVIQSKDATIQELKEKIAYLEAENLEMHDRME 345
+ +Q ++ ++ +EK+ E + ++M+
Sbjct: 534 EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
Score = 50.8 bits (120), Expect = 2e-06
Identities = 68/321 (21%), Positives = 134/321 (41%), Gaps = 43/321 (13%)
Query: 44 QKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEV 103
+K T ++ HS E SH H+E ++ L+ + I +L+ +
Sbjct: 76 KKINNGTNPETTTSGGCHSPEDEQKASHQ-HQEALRRELEAQVQTIRILTCQKTELQMAL 134
Query: 104 QYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDT 163
Y Q A L+ D+ S+L + + Q+ +A+ + + D
Sbjct: 135 YYSQHAVKQLEGEARDLISRLHDSW-------------KFAGELEQALSAVATQKKKADR 181
Query: 164 CINE--------DVESLRKTVQD-----LLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 210
I E +E R T+ D AKLQE + +S+ ++ + +R+ E+
Sbjct: 182 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 241
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAE 270
+ + L ++ Q +AE L + L + + QA +V E E+ N Q +
Sbjct: 242 AKLLLPQQ-----QLQAEADHLGKELQSVSAKLQA---QVEENELW-------NRLNQQQ 286
Query: 271 REKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI 330
EK E+++ EKI ++ ++ Q+ K+R+ E + + ++ ++ + E +EKI
Sbjct: 287 EEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 331 AYLEAENLEMHDRMEHLIEKQ 351
LE E + +++ EK+
Sbjct: 347 RELE-EKMHEQEKIREQEEKR 366
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 7e-10
Identities = 63/289 (21%), Positives = 136/289 (47%), Gaps = 31/289 (10%)
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 147
D+ + EKN +L+ +++ ++ ++ +Q +D+ KL+R L +Q++QV ++
Sbjct: 213 DEELKEKNA-ELQEKLRLVESEKSEIQLNVKDLKRKLER-AQLLLPQQQLQVEADRLGKE 270
Query: 148 SQSPTALYSSPPEVDTCIN--------------EDVESLRKTV--QDLLAKLQEAKRQHQ 191
QS +A + E + N E ++ + + Q+L + QE K Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 192 SDCV--------AFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 243
+ + E + R + + + ++ +E+++ ++E ++ E ++ E E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 244 QALLAKVREGEVALEE-LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKV 302
K+RE E +E + + + EK E+E+ EKI L++M++ Q+ K+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 303 RQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQ 351
R++ E++Q + +Q ++ IQ +EKI E E R E L++++
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKI----QEQEEKTWRQEKLLKQE 495
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/333 (18%), Positives = 144/333 (43%), Gaps = 37/333 (11%)
Query: 31 QGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKM 90
Q ++ D L Q K A V + + L + E EE I+ +KM
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ-----EQEEKM 313
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQS 150
++ + + E + QE + + + E I R D + RQE + + E+ +
Sbjct: 314 CEQELKIREQEEKMWRQEEK--MHEQEEKI-----REQEDKMWRQE-EKIREQEEKIREQ 365
Query: 151 PTALYSSPPEV---DTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 207
++ ++ D I E E + + Q+ + QE KRQ + + R +++
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWR--QEEKIREQEEKRQEK---------MWRQEKK 414
Query: 208 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEE----LRSN 263
+ + ++ +E+ + ++E ++ EL+ + E + + + K++E E ++E ++
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 264 NADCQAEREKAATLEK------EVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQ 317
Q + EK EK ++ EK+ ++ + Q+ K+++ E++Q + ++
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534
Query: 318 SKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 350
++ + + +EK+ E E+ +R+ L +K
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 37.0 bits (84), Expect = 0.031
Identities = 37/188 (19%), Positives = 80/188 (42%), Gaps = 27/188 (14%)
Query: 190 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 249
H V + + +E + ++ L R E+ + + ELQ +L +E+E +
Sbjct: 181 HFDHAVRMGTYIEKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
Query: 250 VREGEVALE--------------------ELRSNNADCQAEREK-------AATLEKEVA 282
V++ + LE EL+S +A QA+ E+ E+++
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
Query: 283 GLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHD 342
EKI ++ + Q+ K+R+ E++ + + ++ I+E ++K+ E + E +
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 343 RMEHLIEK 350
++ EK
Sbjct: 361 KIREQEEK 368
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 62.4 bits (150), Expect = 7e-10
Identities = 63/289 (21%), Positives = 136/289 (47%), Gaps = 31/289 (10%)
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 147
D+ + EKN +L+ +++ ++ ++ +Q +D+ KL+R L +Q++QV ++
Sbjct: 213 DEELKEKNA-ELQEKLRLVESEKSEIQLNVKDLKRKLER-AQLLLPQQQLQVEADRLGKE 270
Query: 148 SQSPTALYSSPPEVDTCIN--------------EDVESLRKTV--QDLLAKLQEAKRQHQ 191
QS +A + E + N E ++ + + Q+L + QE K Q
Sbjct: 271 LQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQ 330
Query: 192 SDCV--------AFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 243
+ + E + R + + + ++ +E+++ ++E ++ E ++ E E
Sbjct: 331 EEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEM 390
Query: 244 QALLAKVREGEVALEE-LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKV 302
K+RE E +E + + + EK E+E+ EKI L++M++ Q+ K+
Sbjct: 391 WRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKL 450
Query: 303 RQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQ 351
R++ E++Q + +Q ++ IQ +EKI E E R E L++++
Sbjct: 451 REVEEKMQEEEEKMQEQEEKIQRQEEKI----QEQEEKTWRQEKLLKQE 495
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/333 (18%), Positives = 144/333 (43%), Gaps = 37/333 (11%)
Query: 31 QGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKM 90
Q ++ D L Q K A V + + L + E EE I+ +KM
Sbjct: 259 QLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQ-----EQEEKM 313
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQS 150
++ + + E + QE + + + E I R D + RQE + + E+ +
Sbjct: 314 CEQELKIREQEEKMWRQEEK--MHEQEEKI-----REQEDKMWRQE-EKIREQEEKIREQ 365
Query: 151 PTALYSSPPEV---DTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 207
++ ++ D I E E + + Q+ + QE KRQ + + R +++
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWR--QEEKIREQEEKRQEK---------MWRQEKK 414
Query: 208 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEE----LRSN 263
+ + ++ +E+ + ++E ++ EL+ + E + + + K++E E ++E ++
Sbjct: 415 MREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Query: 264 NADCQAEREKAATLEK------EVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQ 317
Q + EK EK ++ EK+ ++ + Q+ K+++ E++Q + ++
Sbjct: 475 EEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMR 534
Query: 318 SKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 350
++ + + +EK+ E E+ +R+ L +K
Sbjct: 535 EQEVRLWQQEEKMQEQEVRLQELEERLGKLGQK 567
Score = 36.6 bits (83), Expect = 0.040
Identities = 37/188 (19%), Positives = 80/188 (42%), Gaps = 27/188 (14%)
Query: 190 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 249
H V + + +E + ++ L R E+ + + ELQ +L +E+E +
Sbjct: 181 HFDHAVRMGTYIEKLTKERDALSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLN 240
Query: 250 VREGEVALE--------------------ELRSNNADCQAEREK-------AATLEKEVA 282
V++ + LE EL+S +A QA+ E+ E+++
Sbjct: 241 VKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMW 300
Query: 283 GLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHD 342
EKI ++ + Q+ K+R+ E++ + + ++ I+E ++K+ E + E +
Sbjct: 301 RQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEE 360
Query: 343 RMEHLIEK 350
++ EK
Sbjct: 361 KIREQEEK 368
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 62.0 bits (149), Expect = 9e-10
Identities = 61/293 (20%), Positives = 131/293 (44%), Gaps = 35/293 (11%)
Query: 93 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT 152
E I QLK E + E N + ++E++ K S ++ V L+ S+
Sbjct: 1338 ESCITQLKKE---LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEA 1394
Query: 153 ALYSSPPE------------------VDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC 194
A+ S + VDT E + +L + V D K E K++ QS
Sbjct: 1395 AISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQ-VDDWSNKFSEWKKKAQS-- 1451
Query: 195 VAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGE 254
+++Q ++ + L+ + +K+ ++ L+ L L ++ + +
Sbjct: 1452 -----RFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDK 1506
Query: 255 VALEELRSN-NADCQAEREKAATLEKEVAGLREKIHHLDDMLKS--QQRKV--RQMIEQL 309
+E+ SN + +++ + LE + +I L+++LK+ QQ+ + ++++++L
Sbjct: 1507 SKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKL 1566
Query: 310 QNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQAR 362
Q+ + + + KD ++E +EKI LE + M +E +K++ H N S +++
Sbjct: 1567 QHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE-TKKKELEHVNLSVKSK 1618
Score = 59.7 bits (143), Expect = 4e-09
Identities = 66/305 (21%), Positives = 138/305 (45%), Gaps = 31/305 (10%)
Query: 76 EIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKL-------REDISSKLDRNL 128
++ + Y +E+ + QL+ ++ ++ R L K ++D+ ++LD +
Sbjct: 801 DVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH- 859
Query: 129 GDSLHRQEIQVVLEKPNGFSQ----SPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQ 184
+ Q++ LEK N + S T +Y S E E + + ++++ +++
Sbjct: 860 --KIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMR 917
Query: 185 EAKRQH----QSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGE-LQRRLLGM 239
E +++ A E ++ E E +++ ++V+QK E+ E L+++LL
Sbjct: 918 EGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQ 977
Query: 240 ET------EHQALLAKVREGEV---ALEELRSNNADCQAEREKAATLEKEVAGLREKIHH 290
E E+ AL +E + LE ++N+A + T +KE ++H
Sbjct: 978 EAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR 1037
Query: 291 --LDDMLKSQQRKVRQMIEQLQNSKAV-IQSKDATIQELKEKIAYLEAENLEMHDRMEHL 347
L+D++ ++K+ Q E+LQ + +Q K+ + ELK+KI E EM+ + L
Sbjct: 1038 RELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1097
Query: 348 IEKQI 352
E+ +
Sbjct: 1098 KEEGV 1102
Score = 54.7 bits (130), Expect = 1e-07
Identities = 55/276 (19%), Positives = 130/276 (47%), Gaps = 42/276 (15%)
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQS 150
+ + + L SE+ + +AR+ KL E++S D+ D + +QE++ +++ Q
Sbjct: 681 VKQTELESLSSELSEVLKARH---KLEEELSVLKDQT--DKM-KQELEAKMDEQKNHHQQ 734
Query: 151 PTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAK----------RQHQSDCVAFEVT 200
+VD+ I E S+++T + L ++ + + ++HQ+ E
Sbjct: 735 ---------QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEAD 785
Query: 201 LSRYQREAEQSNVALQ-------REEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREG 253
+ R + E +Q++ L ++ + E ++ +LQ++LL +ETE L +V E
Sbjct: 786 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV 845
Query: 254 EVALEELRSN-NADCQAEREKAATLEKEVAGLREKIHHLDDMLKS-------QQRKVRQM 305
E +++ + +A ++ LEK+ + + +K+ L + +S +Q + +Q+
Sbjct: 846 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 905
Query: 306 IEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMH 341
+ + +N ++Q ++ +E++ L A+ +H
Sbjct: 906 LVEKEN--MILQMREGQKKEIEILTQKLSAKEDSIH 939
Score = 52.8 bits (125), Expect = 5e-07
Identities = 69/297 (23%), Positives = 129/297 (43%), Gaps = 27/297 (9%)
Query: 71 HDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDR---N 127
H + +++ L+ +S + ++ IN LK E+ + +CL+ ED SK+++ N
Sbjct: 1456 HQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESN 1515
Query: 128 LGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQE-- 185
L L Q + ++E + +Q T S EV N+ + K + L QE
Sbjct: 1516 LETELKSQTAR-IMELEDHITQK-TIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELG 1573
Query: 186 -----AKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGME 240
++ + + E + + E E L+ V+ KE E+ L+ RL E
Sbjct: 1574 EEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRL---E 1630
Query: 241 TEHQALLAKV-REGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ 299
+E A LA++ R+ E + ++ E+E E+ G + L+ L+ ++
Sbjct: 1631 SESAAKLAELKRKAEQKIAAIKKQLLSQMEEKE-----EQYKKGTESHLSELNTKLQERE 1685
Query: 300 RKVRQMIEQLQNSKAVIQSKDATI---QELKEKIAYLEAENLEMHDRMEHLIEKQIS 353
R+V + E+L K+V S+ T+ + K AY E E + ++ E++IS
Sbjct: 1686 REVHILEEKL---KSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKIS 1739
Score = 49.7 bits (117), Expect = 5e-06
Identities = 73/339 (21%), Positives = 141/339 (41%), Gaps = 29/339 (8%)
Query: 27 RLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGH--EEIIKVYLKG 84
+L + E T EL ++ K M ++SAG S A +E++ E + +V+ +
Sbjct: 980 KLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRE 1039
Query: 85 RSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEI--QVVLE 142
+ I EK +NQ E+Q I E + LQ+ ++++ + L ++E+ ++
Sbjct: 1040 LNDVISIWEKKLNQQAEELQEIHEIQ--LQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1097
Query: 143 KPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLS 202
K G Q DT +NE E L++ + + Q+ + + ++ EV L+
Sbjct: 1098 KEEGVKQ------------DTTLNELQEQLKQKSAHVNSLAQD-ETKLKAHLEKLEVDLN 1144
Query: 203 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEE--L 260
+ +E L + E+ + +V EL +L + E Q+L + + +LE+ L
Sbjct: 1145 KSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSL 1204
Query: 261 RSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNS----KAVI 316
+ + +K A L K + L ++ S+ + I Q+ K +
Sbjct: 1205 EFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1264
Query: 317 QSKDATIQELKEKIAYLEAE----NLEMHDRMEHLIEKQ 351
K T+ EL+ ++ L E N+ L EK+
Sbjct: 1265 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKE 1303
Score = 46.6 bits (109), Expect = 4e-05
Identities = 65/274 (23%), Positives = 121/274 (44%), Gaps = 37/274 (13%)
Query: 107 QEARNCLQKLREDISSKLDRNLGDS-----LHRQEI-QVVLEKPNGFSQSPTALYSSPPE 160
Q+ + ++KLRE + + L D H +E+ + LEK + +L S E
Sbjct: 636 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSE 695
Query: 161 VDTC---INEDVESLR----KTVQDLLAKLQEAKRQHQSDCVAF----EVTLSRYQR--- 206
V + E++ L+ K Q+L AK+ E K HQ + EV++ R ++
Sbjct: 696 VLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALK 755
Query: 207 -EAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNA 265
+ Q + L+ + +++ +A V L+ + E E Q AK L+ +S +
Sbjct: 756 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAK-------LDVFQSYQS 808
Query: 266 DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQE 325
A E+ E+++A L++K L D+ + +Q+ E K V DA +
Sbjct: 809 ---ATHEQTKAYEEQLAQLQQK---LLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQ 862
Query: 326 LKEKIAYLEAENLEMHDRMEHL---IEKQISHGN 356
+++ + LE +N EM +++ L E ++ GN
Sbjct: 863 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 896
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/213 (23%), Positives = 89/213 (41%), Gaps = 21/213 (9%)
Query: 160 EVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREE 219
E+D+C+ E R +++L +K ++ + Q D L E + + +Q +
Sbjct: 1858 ELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPK- 1916
Query: 220 DRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNA--------DCQAER 271
+ EA+ +L+ +L G E E Q L ++ + L LR + + ER
Sbjct: 1917 -LLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQER 1975
Query: 272 EKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIA 331
E+ E+E L+ + LK R+ + Q + Q + TI+E K
Sbjct: 1976 EEKIKQEQEDLELKH-----NSTLKQLMREFNTQLAQKE------QELEMTIKETINKAQ 2024
Query: 332 YLEAENLEMHDRMEHLIEKQISHGNFSTQARAK 364
+EAE LE H + + K+I+ + + AK
Sbjct: 2025 EVEAELLESHQEETNQLLKKIAEKDDDLKRTAK 2057
Score = 41.2 bits (95), Expect = 0.002
Identities = 47/266 (17%), Positives = 109/266 (40%), Gaps = 47/266 (17%)
Query: 58 SAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLR 117
S H + +L+ + + ++ L G +K K I +L+ +++ +++ Q+
Sbjct: 1908 SKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH---QQEL 1964
Query: 118 EDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQ 177
E + + D+ + + +++ + L+ + Q E +T + + + L T++
Sbjct: 1965 EILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMR-------EFNTQLAQKEQELEMTIK 2017
Query: 178 DLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLL 237
+ + K QE + + L +Q E Q + ++D +++ E+
Sbjct: 2018 ETINKAQEVEAE----------LLESHQEETNQLLKKIAEKDDDLKRTAKRYEEI----- 2062
Query: 238 GMETEHQALLAKVREGEVALEELRSNNADCQAEREKAAT-------LEKEVA-------- 282
++ + + AKVR+ + LEEL+ + E L+ ++A
Sbjct: 2063 -LDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISD 2121
Query: 283 ------GLREKIHHLDDMLKSQQRKV 302
RE+IH+L+D LK ++ V
Sbjct: 2122 SKLKEQEFREQIHNLEDRLKKYEKNV 2147
Score = 40.8 bits (94), Expect = 0.002
Identities = 80/380 (21%), Positives = 145/380 (38%), Gaps = 85/380 (22%)
Query: 30 LQGELTGDELEHIAQKAGRKTYAMVSSH--------------------------SAGHSL 63
LQ LT E E + Q+ G++ VSSH GH L
Sbjct: 1741 LQRNLT--EKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH-L 1797
Query: 64 ASELVESHDGHEEIIKVYLKGRSGDKMIHEK-NINQLKSEVQYIQEARNCLQKLREDISS 122
EL E + + I+ +++ G I K N+ + +VQ + + ++ E
Sbjct: 1798 QEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIK 1857
Query: 123 KLDRNL--GDSLHRQEIQVVL---EKPNGFSQ-----SPTALYSSPPE-------VDTCI 165
+LD L +HR E++ + EK Q PT L E V +
Sbjct: 1858 ELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL 1917
Query: 166 NEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREED----- 220
++E+ ++ LA + K++ + V + L ++E +Q L++E D
Sbjct: 1918 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREE 1977
Query: 221 --RVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAER------- 271
+ EQ++ E+ M + L K +E E+ ++E + + +AE
Sbjct: 1978 KIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEE 2037
Query: 272 ---------------EKAATLEKEVAGLRE-----KIHHLDDMLKSQQRKVRQMIEQLQN 311
++ A +E+ RE K+ L L+ Q+K +Q +EQ +N
Sbjct: 2038 TNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2097
Query: 312 SKAVIQSKDATIQELKEKIA 331
+ + TI EL+ ++A
Sbjct: 2098 P----GNDNVTIMELQTQLA 2113
Score = 39.7 bits (91), Expect = 0.005
Identities = 74/311 (23%), Positives = 133/311 (42%), Gaps = 60/311 (19%)
Query: 93 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT 152
E+ +LK+E+ E ++K E+ L + L S +QE+ V++K
Sbjct: 427 EEARRKLKAEMD---EQIKTIEKTSEEERISLQQEL--SRVKQEVVDVMKK--------- 472
Query: 153 ALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC-VAFEVTLSRYQREAEQS 211
SS ++ + L + Q+L KLQ +R+ Q VA E + S Y +
Sbjct: 473 ---SSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK----- 524
Query: 212 NVALQREEDRVEQKEAEVGELQRRLLGMETEH---------QALLAKVREGEVALEELRS 262
+ +E+++ E E ELQ++ + E+E+ + ++ E E +LE+
Sbjct: 525 ---ISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQ 581
Query: 263 NNAD--------CQAEREKAATLEKEVAGLREKIHHLDDMLKSQQ-----RKVRQMIEQL 309
N + +AE+ K KE+ + EK + LK QQ K++ + +Q
Sbjct: 582 ENKNQSKDLAVHLEAEKNKH---NKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQY 638
Query: 310 QNSKAVIQSKDATIQE--LKEKIAYLEAENLEMHDR-MEHLIEKQISHGNFSTQ------ 360
Q ++ K +E LK+K +A EM+++ +E L KQ + S++
Sbjct: 639 QTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLK 698
Query: 361 ARAKTENPGSI 371
AR K E S+
Sbjct: 699 ARHKLEEELSV 709
Score = 33.5 bits (75), Expect = 0.34
Identities = 55/303 (18%), Positives = 122/303 (40%), Gaps = 48/303 (15%)
Query: 93 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR-----QEIQVVLEKPNGF 147
E++++ + + + A LQ+ ++ + L ++ SL R +E+Q+ +
Sbjct: 147 ERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHL 206
Query: 148 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 207
+ A + + + V L++ +++ + K Q + A EV E
Sbjct: 207 QEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQA-EVFTKEENPE 265
Query: 208 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 267
++ V ED K E LQ+R+ E LL + +E ++S+ C
Sbjct: 266 SDGEPVV----EDGTSVKTLET--LQQRVKRQEN----LLKRCKE------TIQSHKEQC 309
Query: 268 QAEREKAATLEKEVAGLREKIHHLDDM-------LKSQQRKVRQMIEQLQNSKAVI---- 316
+ L++++ +++ + D+ L +Q R + +IEQL+ K ++
Sbjct: 310 TLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAET 369
Query: 317 --------QSKDATIQELKEKIAYLEAENLEMHDRME-------HLIEKQISHGNFSTQA 361
+ K+ I +L+ +I + + E+ ++ E +EK +S + +A
Sbjct: 370 KRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEA 429
Query: 362 RAK 364
R K
Sbjct: 430 RRK 432
Score = 29.3 bits (64), Expect = 6.4
Identities = 53/278 (19%), Positives = 107/278 (38%), Gaps = 39/278 (14%)
Query: 75 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 134
EE +K +S ++ N Q +++ C+QK E+ S L RNL
Sbjct: 1692 EEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNL------ 1745
Query: 135 QEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDC 194
++ L E + ++ E +R Q+ L KL+ A+ + D
Sbjct: 1746 -------------TEKEKLLQRVGQEKEETVSSHFE-MRCQYQERLIKLEHAEAKQHED- 1790
Query: 195 VAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGE 254
+ + Q E E+ N + +KE +Q + +E + ++E E
Sbjct: 1791 ---QSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAK-QNLENVFDDVQKTLQEKE 1846
Query: 255 VA---LEELRSNNADCQAEREKAATLE-KEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQ 310
+ LE+ C +++ +E +E+ EK+ L M + K +++E+
Sbjct: 1847 LTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQM--DGRNKPTELLEENT 1904
Query: 311 NSKA--------VIQSKDATIQELKEKIAYLEAENLEM 340
K+ ++ + +A +L+ K+A E E ++
Sbjct: 1905 EEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKL 1942
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 61.6 bits (148), Expect = 1e-09
Identities = 71/366 (19%), Positives = 166/366 (45%), Gaps = 30/366 (8%)
Query: 11 VDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVES 70
+DV E V + L L + D++E++ + + + VS L + ++
Sbjct: 557 LDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQN 616
Query: 71 HDGHEEIIKVYLKGRSGDKMIHEKN--INQLKSEVQYIQEARNCLQKLREDISSKLDRNL 128
+ I ++ + D + K+ + + ++EV+ +++ + L++L E++ + +
Sbjct: 617 EEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENL-----KKV 671
Query: 129 GDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKR 188
+ + ++VL + Q L + ++ N VE+L+ ++ A+L AK+
Sbjct: 672 AFDVKMENEKLVLACEDVRHQLEECLAGNN-QLSLEKNTIVETLKMEKGEIEAELCWAKK 730
Query: 189 QHQSDCVAFEVTLSRYQREAEQSNVALQREEDRV----EQKEAEVGELQRRLLGMETEHQ 244
+ + +E T+ + ALQ E + + ++K+ E+ EL++ + M+T+H+
Sbjct: 731 RLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHK 790
Query: 245 A--------------LLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHH 290
L + + E+ +E+L+ ++ Q E +K + ++ LR+ I
Sbjct: 791 ETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEE 850
Query: 291 LDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELK--EKIAYLEAENLEMHDRMEHLI 348
D L S + + + E+L+ + QS+ A + + K + + L +E +++ EHL
Sbjct: 851 KDRSLGSMKEENNHLQEELERLREE-QSRTAPVADPKTLDSVTELASEVSQLNTIKEHL- 908
Query: 349 EKQISH 354
E++I H
Sbjct: 909 EEEIKH 914
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/274 (20%), Positives = 111/274 (40%), Gaps = 32/274 (11%)
Query: 93 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNG--FSQS 150
+K Q+K ++ Q+ +Q ++ + + L + LH+ + QV+++ N
Sbjct: 1212 DKLKQQVKKMEEWKQQVMTTVQNMQHESAQ-----LQEELHQLQAQVLVDSDNNSKLQVD 1266
Query: 151 PTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 210
T L S + +T + + L + VQ + +L K LS Q
Sbjct: 1267 YTGLIQSYEQNETKLKNFGQELAQ-VQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQ 1325
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNN------ 264
S L+ + V + +E+ ++ E + L ++E + + L+ NN
Sbjct: 1326 SAECLRASKSEVLSESSEL---------LQQELEELRKSLQEKDATIRTLQENNHRLSDS 1376
Query: 265 --ADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSK--- 319
A + ER++ + E+ L+EK L +LK + ++ +QL +S +K
Sbjct: 1377 IAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNE 1436
Query: 320 ----DATIQELKEKIAYLEAENLEMHDRMEHLIE 349
+ LKE+I LE + ++ E ++E
Sbjct: 1437 NELLRQAVTNLKERILILEMDIGKLKGENEKIVE 1470
Score = 42.4 bits (98), Expect = 7e-04
Identities = 70/344 (20%), Positives = 139/344 (40%), Gaps = 69/344 (20%)
Query: 61 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 120
H L ++++ D + ++ Y +G +E+N +LK+ Q + + ++ + +L
Sbjct: 1247 HQLQAQVLVDSDNNSKLQVDY----TGLIQSYEQNETKLKNFGQELAQVQHSIGQL---- 1298
Query: 121 SSKLDRNLG--DSLHRQEIQVVLEKPNGFSQSPTALYSSPPEV----DTCINEDVESLRK 174
+ D LG D + Q L P QS L +S EV + +++E LRK
Sbjct: 1299 CNTKDLLLGKLDIISPQLSSASLLTP----QSAECLRASKSEVLSESSELLQQELEELRK 1354
Query: 175 TVQDLLAKLQEAKRQHQ--SDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK------- 225
++Q+ A ++ + + SD +A L R + E S + +E+ V QK
Sbjct: 1355 SLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDL 1414
Query: 226 --------------------------EAEVGELQRRLLGMETEHQALLAKVR-EGEVALE 258
V L+ R+L +E + + K++ E E +E
Sbjct: 1415 LIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMD----IGKLKGENEKIVE 1470
Query: 259 ELRSNNADCQAEREKAATL-------EKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQN 311
R + QA +E E E ++EK + +LK +++ + QL N
Sbjct: 1471 TYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKTGELNQLLN 1530
Query: 312 SKAVIQSKDATIQELKEKIAYL----EAENLEMHDRMEHLIEKQ 351
+ +Q K Q+ ++++ + EN + + ++ L +K+
Sbjct: 1531 AVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKE 1574
Score = 40.4 bits (93), Expect = 0.003
Identities = 78/374 (20%), Positives = 145/374 (38%), Gaps = 74/374 (19%)
Query: 28 LTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSG 87
L+ EL ELE + + K + + H L+ + + +
Sbjct: 1338 LSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSE--------------- 1382
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLRED----ISSKLDRNLG-----------DSL 132
+ K Q SE++ ++E ++ LQKL ++ I +K D+ L + L
Sbjct: 1383 ---LERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENEL 1439
Query: 133 HRQEIQVVLEKPNGFSQSPTALYSSPPE-VDTCINEDVESLRKTVQDLLAKLQEAKRQHQ 191
RQ + + E+ L + V+T ++ E + +Q+ K R+ +
Sbjct: 1440 LRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETE--YQALQETNMKFSMMLREKE 1497
Query: 192 SDC-------VAFEVTLSRYQ--------------REAEQSNVALQREEDRV----EQKE 226
+C +AFE L + + ++ V Q+E D+V +QK+
Sbjct: 1498 FECHSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQ 1557
Query: 227 AEVGELQ---RRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAG 283
E LQ +RL E L ++R LE S + A ++ A L K+V
Sbjct: 1558 MENTALQNEVQRLRDKEFRSNQELERLRNH--LLESEDSYTREALAAEDREAKLRKKVTV 1615
Query: 284 LREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVI-QSKDATIQEL-----KEKIAYLEAEN 337
L EK+ + +++ + +E LQ V+ + +D T +L + K L N
Sbjct: 1616 LEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLAN 1675
Query: 338 LEMHDRMEHLIEKQ 351
L+M +EH +++
Sbjct: 1676 LQM--VLEHFQQEE 1687
Score = 38.5 bits (88), Expect = 0.010
Identities = 81/390 (20%), Positives = 155/390 (39%), Gaps = 69/390 (17%)
Query: 14 HPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAG--HSLASELVESH 71
H +D G DI+ + +E+ + + G + +S + G +S SE+ +
Sbjct: 158 HDDDMDFG--DIISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKL- 214
Query: 72 DGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDS 131
+ IIK + RS + I+ + E+ +Q A QKL E IS + L D
Sbjct: 215 ---QNIIKELKQNRS-------QEIDDHQHEMSVLQNAHQ--QKLTE-ISRRHREELSDY 261
Query: 132 LHR-QEIQVVLEKPNG--FSQSPTALYSSPPEVDTCINEDVESLRKTVQ----------- 177
R +E++ +L++ + +Y + E VES +K Q
Sbjct: 262 EERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKK 321
Query: 178 --------DLLAKLQEA----KRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK 225
D+L + QE KRQ +C ++ S+ Q A + + + +E + Q
Sbjct: 322 LSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQS 381
Query: 226 EA--EVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAA-TLEKEVA 282
+ EV LQ+ L E E L + ++ +A + L+ E+EK+ + EKE
Sbjct: 382 ASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEEL 441
Query: 283 ----------------------GLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKD 320
L ++H L L+++++++ Q I + + A I+ D
Sbjct: 442 QMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELD 501
Query: 321 ATIQELKEKIAYLEAENLEMHDRMEHLIEK 350
QE + + ++ + + + + +I K
Sbjct: 502 RQNQEATKHMILIKDQLSKQQNEGDSIISK 531
Score = 37.4 bits (85), Expect = 0.023
Identities = 69/333 (20%), Positives = 135/333 (40%), Gaps = 66/333 (19%)
Query: 66 ELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQ----EARNCLQKLRE--- 118
EL + + EE+ + +G SG I +++ +Q +Q E+ +++L +
Sbjct: 257 ELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIK 316
Query: 119 DISSKLD--RNLGDSLHRQEIQVVLEK------------------PNGFSQSPTALYSSP 158
DI+ KL N D L R++ Q+ +EK P+ QS T
Sbjct: 317 DINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKER 376
Query: 159 PEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQR----EAEQSNVA 214
+ E+V L++ + D ++ +Q + +A E L R E E+S ++
Sbjct: 377 ILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLA-EDNLKLKMRIEVLEKEKSLLS 435
Query: 215 LQREEDRVE----QKEAEV------------GELQRRLLGMETEHQALLAKVREGEVAL- 257
++EE ++ E EV EL L +E + Q L + E E +
Sbjct: 436 QEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIA 495
Query: 258 --EELRSNNADC---------QAEREK------AATLEKEVAGLREKIHHLDDMLKSQQR 300
EEL N + Q +++ + L++++ ++++H L+D +
Sbjct: 496 EIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITK 555
Query: 301 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYL 333
++ E+L S+ + T Q+L++K+ L
Sbjct: 556 ELDVQKEKLIQSEVALNDLHLTKQKLEDKVENL 588
Score = 37.4 bits (85), Expect = 0.023
Identities = 66/359 (18%), Positives = 141/359 (39%), Gaps = 62/359 (17%)
Query: 37 DELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNI 96
+EL+ +Q + + SL S E++ EE+ ++ + + K +
Sbjct: 829 EELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTL 888
Query: 97 NQLKSEVQYIQEARNCLQKLREDISSKL----DRNLGDSLHRQEIQVVLEKPNGFSQSPT 152
+ + + + + L E+I D+N Q +Q ++ + F
Sbjct: 889 DSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHE 948
Query: 153 ALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSD-CVAFEVT----------- 200
+ ++ ++ +E+++SL+KT++ + +L E ++ Q+D F+ T
Sbjct: 949 QMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGS 1008
Query: 201 ----LSRYQREA---------------EQSNVALQREEDRVEQKEAEVGELQRRLLGMET 241
LS+ + E + N++L ++ D++ + E VG+L + + +
Sbjct: 1009 EKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDE--VGKLTQIIQQKDL 1066
Query: 242 EHQALLAKVREGEVALEE--LRSNNADCQAEREKAATL----EKEVAGLREKIHHLDDM- 294
E QAL A++ + L+ EREK + +E + L+ + H + D+
Sbjct: 1067 EIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIV 1126
Query: 295 ---------LKSQQRKVRQMIEQ---------LQNSKAVIQSKDATIQELKEKIAYLEA 335
L+ + +K+ E +QN +I+ KD I L +K L A
Sbjct: 1127 AAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLA 1185
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 61.6 bits (148), Expect = 1e-09
Identities = 66/283 (23%), Positives = 128/283 (45%), Gaps = 16/283 (5%)
Query: 75 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 134
EE+ K+ K + ++M E+ K+E++ +Q+ +K E + ++ R +SL R
Sbjct: 604 EELEKLESKRKLIEEM--EEKQKSDKAELERMQQEVETQRKETEIVQLQI-RKQEESLKR 660
Query: 135 QEIQV------VLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKR 188
+ + +L + F + E++ E VQ+ L +L+E
Sbjct: 661 RSFHIENKLKDLLAEKEKFEEERLR---EQQEIELQKKRQEEETFLRVQEELQRLKELNN 717
Query: 189 QHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLA 248
+++ L + Q+E ++ L+ E+ R+E++E E L L E Q ++
Sbjct: 718 NEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQ 777
Query: 249 KVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDD-MLKSQQRKVRQMIE 307
+R GEV + + D + RE +++ AG E L+ L+ + K RQ+++
Sbjct: 778 LLRRGEV--QWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVK 835
Query: 308 QLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 350
+ K ++Q KD +E++E+ LE E HD+ L+EK
Sbjct: 836 LVNLEKDLVQQKDILKKEVQEEQEILECLKCE-HDKESRLLEK 877
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 61.2 bits (147), Expect = 2e-09
Identities = 77/345 (22%), Positives = 146/345 (42%), Gaps = 39/345 (11%)
Query: 18 QAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEI 77
+A +++ + TL+ ++ +E A++ R + S + + EL D E +
Sbjct: 1240 KAKANLEKMCRTLEDQM--NEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEAL 1297
Query: 78 IKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEI 137
I +G+ E QL+ EV+ + LQ R D ++ ++ + E+
Sbjct: 1298 ISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
Query: 138 QVVLEKPNGFSQSPTALYSSPPEVDTCIN-EDVESLRKTVQDLLAKLQEAKRQHQSDCVA 196
Q VL K N S A + + E D E++E +K + L + +EA + C +
Sbjct: 1358 QRVLSKAN----SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSS 1413
Query: 197 FEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVA 256
E T R Q E E V VE+ A L ++ + +LA+ ++
Sbjct: 1414 LEKTKHRLQNEIEDLMVD-------VERSNAAAAALDKK----QRNFDKILAEWKQ---- 1458
Query: 257 LEELRSNNADCQAEREKAATLEKEVAGLR----EKIHHLDDML---KSQQRKVRQMIEQL 309
+ + ++ ++ +++A +L E+ L+ E + HL+ K+ Q ++ + EQL
Sbjct: 1459 --KYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQL 1516
Query: 310 QNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISH 354
+S TI EL++ LEAE +E+ +E E + H
Sbjct: 1517 GSS-------GKTIHELEKVRKQLEAEKMELQSALEE-AEASLEH 1553
Score = 48.9 bits (115), Expect = 8e-06
Identities = 57/263 (21%), Positives = 120/263 (45%), Gaps = 37/263 (14%)
Query: 93 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPN--GFSQS 150
EK + +K E ++EA + R+++ K+ L + Q +QV E+ N +
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQ-LQVQAEQDNLADAEER 904
Query: 151 PTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAF-------EVTLSR 203
L + +++ + E E L +++ A+L KR+ + +C E+TL++
Sbjct: 905 CDQLIKNKIQLEAKVKEMNERLEDE-EEMNAELTAKKRKLEDECSELKRDIDDLELTLAK 963
Query: 204 YQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSN 263
++E + E +V L + G++ ++AK+ + + AL+E
Sbjct: 964 VEKEKHAT--------------ENKVKNLTEEMAGLD----EIIAKLTKEKKALQEAHQQ 1005
Query: 264 NA-DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDAT 322
D QAE +K TL K L +++ L+ L+ Q++KVR +E+ + + +
Sbjct: 1006 ALDDLQAEEDKVNTLTKAKVKLEQQVDDLEGSLE-QEKKVRMDLERAK------RKLEGD 1058
Query: 323 IQELKEKIAYLEAENLEMHDRME 345
++ +E I LE + ++ +R++
Sbjct: 1059 LKLTQESIMDLENDKQQLDERLK 1081
Score = 47.4 bits (111), Expect = 2e-05
Identities = 71/368 (19%), Positives = 163/368 (44%), Gaps = 61/368 (16%)
Query: 37 DELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNI 96
D+LE K ++ +A + L E G +EII K + + H++ +
Sbjct: 955 DDLELTLAKVEKEKHATENK-------VKNLTEEMAGLDEIIAKLTKEKKALQEAHQQAL 1007
Query: 97 NQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNG--------FS 148
+ L++E ++ N L K + + ++D G +++++ LE+
Sbjct: 1008 DDLQAE----EDKVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQ 1063
Query: 149 QSPTALYSSPPEVD----------TCINEDVE-------SLRKTVQDLLAKLQEAKRQHQ 191
+S L + ++D +N +E L+K +++L A+++E + + +
Sbjct: 1064 ESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELE 1123
Query: 192 SDCVA---FEVTLSRYQREAEQSNVALQR-------EEDRVEQKEAEVGELQRRLLGMET 241
++ A E S RE E+ + L+ + + +++EAE +++R L
Sbjct: 1124 AERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1183
Query: 242 EHQALLAKVREGEV-ALEELRSNNADCQAEREKAATLEKEVAGLREKI----HHLDDMLK 296
+H+A A +R+ ++ EL + Q ++K LEKE + + ++ +++ ++K
Sbjct: 1184 QHEATAAALRKKHADSVAELGEQIDNLQRVKQK---LEKEKSEFKLELDDVTSNMEQIIK 1240
Query: 297 SQ---QRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMH---DRMEHLIEK 350
++ ++ R + +Q+ ++ + ++ +L + A L+ EN E+ D E LI
Sbjct: 1241 AKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALI-S 1299
Query: 351 QISHGNFS 358
Q++ G +
Sbjct: 1300 QLTRGKLT 1307
Score = 45.4 bits (106), Expect = 9e-05
Identities = 77/404 (19%), Positives = 155/404 (38%), Gaps = 76/404 (18%)
Query: 12 DVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHS----LASEL 67
++ E A V+ LR L EL +E+ ++AG T + + + + +L
Sbjct: 1121 ELEAERTARAKVEKLRSDLSREL--EEISERLEEAGGATSVQIEMNKKREAEFQKMRRDL 1178
Query: 68 VESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD-- 125
E+ HE K H ++ +L ++ +Q + L+K + + +LD
Sbjct: 1179 EEATLQHEATAAALRKK-------HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1231
Query: 126 ------------------RNLGDSL--HRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCI 165
R L D + HR + + N + L + E+ +
Sbjct: 1232 TSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 166 NED---VESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRV 222
+E + L + +L++ KRQ + + A Q ++ ++ E+
Sbjct: 1292 DEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEET 1351
Query: 223 EQK----------EAEVGELQ--------RRLLGMETEHQALLAKVREGEVALEELRSNN 264
E K +EV + + +R +E + L +++E E A+E + N
Sbjct: 1352 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAV---N 1408
Query: 265 ADCQAEREKAATLEKEV--------------AGLREKIHHLDDMLKSQQRKVRQMIEQLQ 310
A C + + L+ E+ A L +K + D +L ++K + +L+
Sbjct: 1409 AKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELE 1468
Query: 311 NSKAVIQSKDATIQELKEKIAYLEA-ENLEMHDRMEHLIEKQIS 353
+S+ +S + +LK AY E+ E+LE R ++++IS
Sbjct: 1469 SSQKEARSLSTELFKLKN--AYEESLEHLETFKRENKNLQEEIS 1510
Score = 44.7 bits (104), Expect = 1e-04
Identities = 55/331 (16%), Positives = 143/331 (43%), Gaps = 36/331 (10%)
Query: 10 LVDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVE 69
+VDV + AA ++D + L QK + SS SL++EL +
Sbjct: 1429 MVDVERSNAAAAALDKKQRNFDKILA-----EWKQKYEESQSELESSQKEARSLSTELFK 1483
Query: 70 SHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLG 129
+ +EE ++ + +K + E+ I+ L ++ + + L+K+R+ + ++
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEE-ISDLTEQLGSSGKTIHELEKVRKQLEAE------ 1536
Query: 130 DSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQ 189
+ E+Q LE+ + I ++E + + + ++++AKR
Sbjct: 1537 ----KMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIE---RKLAEKDEEMEQAKRN 1589
Query: 190 HQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAK 249
H + + +L R ++ ++ E + + E ++ R + + ++L +
Sbjct: 1590 HLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSL 1649
Query: 250 VREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQL 309
+++ ++ L++ N D +E A +E+ +++L+++ ++R ++EQ
Sbjct: 1650 LKDTQIQLDDAVRANDDL---KENIAIVERR-----------NNLLQAELEELRAVVEQT 1695
Query: 310 QNSKAVIQSKDATIQELKEKIAYLEAENLEM 340
+ S+ + + + + E E++ L ++N +
Sbjct: 1696 ERSRKLAEQE---LIETSERVQLLHSQNTSL 1723
Score = 42.7 bits (99), Expect = 6e-04
Identities = 53/283 (18%), Positives = 116/283 (40%), Gaps = 43/283 (15%)
Query: 93 EKNINQLKSEVQYIQEARNCLQKLREDISSKLDR---NLGDSLHRQEIQVVLEKPNG--- 146
+ I +L+ E++ + AR ++KLR D+S +L+ L ++ +Q+ + K
Sbjct: 1112 QARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEF 1171
Query: 147 -----------FSQSPTALYSSPPEVDTC--INEDVESLRKTVQDL-------------- 179
TA D+ + E +++L++ Q L
Sbjct: 1172 QKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDV 1231
Query: 180 ---LAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRL 236
+ ++ +AK + C E ++ ++ +AE++ ++ + + + E GEL R+L
Sbjct: 1232 TSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 237 LGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLK 296
E +AL++++ G++ + D + + E+ + +A + H D+L+
Sbjct: 1292 ----DEKEALISQLTRGKLTYTQ---QLEDLKRQLEEEVKAKNALAHALQSARHDCDLLR 1344
Query: 297 SQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLE 339
Q + + +LQ + S+ A + E A E LE
Sbjct: 1345 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE 1387
Score = 40.4 bits (93), Expect = 0.003
Identities = 47/263 (17%), Positives = 108/263 (41%), Gaps = 34/263 (12%)
Query: 97 NQLKSEVQYIQEARNCLQKLREDISSKLDRN-LGDSLHRQEIQVVLEKPNGFSQSPTALY 155
+ LK + ++ N LQ E++ + +++ L QE+ E+ T+L
Sbjct: 1665 DDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLI 1724
Query: 156 SSPPEVDT---------------CINEDVESLRKTVQDLLAKLQEAKRQHQSDCVA---- 196
+ ++D C N + E +K + D +E K++ +
Sbjct: 1725 NQKKKMDADLSQLQTEVEEAVQECRNAE-EKAKKAITDAAMMAEELKKEQDTSAHLERMK 1783
Query: 197 --FEVTLSRYQREAEQSN-VALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREG 253
E T+ Q +++ +AL+ + ++++ EA V EL+ L + + + +R+
Sbjct: 1784 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKS 1843
Query: 254 EVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSK 313
E ++EL Q E ++ K + L++ + L +K+ +R+ + EQ +
Sbjct: 1844 ERRIKEL-----TYQTEEDR-----KNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNL 1893
Query: 314 AVIQSKDATIQELKEKIAYLEAE 336
+ + + E +E+ E++
Sbjct: 1894 SKFRKVQHELDEAEERADIAESQ 1916
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 60.5 bits (145), Expect = 3e-09
Identities = 49/272 (18%), Positives = 128/272 (47%), Gaps = 9/272 (3%)
Query: 83 KGRSGDKMIHEKN--INQLKSEVQYIQEARNCLQKLRED--ISSKLDRNLGDSLHRQEIQ 138
K R ++M+ EK I +L+ ++ ++ R +K +E+ I + R ++ ++ +
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 139 VVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFE 198
+ E+ + ++ ++ E R+ +++ QE K + Q + +
Sbjct: 485 KIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR--QEEKIREQEEIWRQK 542
Query: 199 VTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALE 258
+ + + + + R+E+++ +E ++ E + ++ E + + K+RE E E
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE---E 599
Query: 259 ELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 318
++R Q + EK E+++ EK+ ++ ++ Q+ K+R+ ++++ + I+
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 659
Query: 319 KDATIQELKEKIAYLEAENLEMHDRMEHLIEK 350
++ +QE +EK+ E + E ++M+ EK
Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 691
Score = 56.2 bits (134), Expect = 5e-08
Identities = 44/256 (17%), Positives = 120/256 (46%), Gaps = 11/256 (4%)
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPNGFS 148
++++ ++ + + IQE +Q+ E I + + R + + RQE +++ EK
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE-EMMWEKEEKMR 413
Query: 149 QSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREA 208
+ ++ ++ E + + +++L K+ E ++ + + E R Q +
Sbjct: 414 RQEEMMWEKEEKMRRQ-EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472
Query: 209 EQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQ 268
++ + R+E+++ ++E ++ E + ++ E K+ E E EE + +
Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEE-------KIHEQEKIREEEKRQEQEEM 525
Query: 269 AEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKE 328
+E+ ++E+ +EKIH ++ ++ Q+ K+ + E++ + + I+ ++ + +E
Sbjct: 526 WRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE 585
Query: 329 KIAYLEAENLEMHDRM 344
KI E + E +++
Sbjct: 586 KIREQEEKIREQEEKI 601
Score = 53.1 bits (126), Expect = 4e-07
Identities = 67/336 (19%), Positives = 134/336 (39%), Gaps = 35/336 (10%)
Query: 44 QKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEV 103
+K T ++ HS E SH H+E ++ L+ + I +L+ +
Sbjct: 149 KKINNGTNPETTTSGGCHSPEDEQKASHQ-HQEALRRELEAQVHTIRILTCQKTELQMAL 207
Query: 104 QYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDT 163
Y Q A L+ D+ S+L + + Q+ +A+ + + D
Sbjct: 208 YYSQHAVKQLEGEARDLISRLHDSW-------------KFAGELEQALSAVATQKKKADR 254
Query: 164 CINE--------DVESLRKTVQD-----LLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 210
I E +E R T+ D AKLQE + +S+ ++ + +R+ E+
Sbjct: 255 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 314
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAE 270
+ + L ++ Q +AE L + L + + QA +V E E+ + +
Sbjct: 315 AKLLLPQQ-----QLQAEADHLGKELQSVSAKLQA---QVEENELWNRLNQQQEEKMWRQ 366
Query: 271 REKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI 330
EK E+++ EKI ++ ++ Q+ K+R+ E + + ++ ++ + E +EK+
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 331 AYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTE 366
E E +++ L EK Q + E
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 462
Score = 51.6 bits (122), Expect = 1e-06
Identities = 41/191 (21%), Positives = 89/191 (46%), Gaps = 23/191 (12%)
Query: 165 INEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQ 224
I+E E +RK + + QE K Q + + RE E+ + R+E+++ +
Sbjct: 545 IHEQEEKIRKQEEKMWR--QEEKMHDQEEKI----------REQEEK---VWRQEEKIRE 589
Query: 225 KEAEVGELQRRLLGMETEHQALLAKVREGEVAL----EELRSNNADCQAEREKAATLEKE 280
+E ++ E + ++ E Q K+ E E + E+++ + + EK EK+
Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK 649
Query: 281 VAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI----AYLEAE 336
+ EKI ++M++ Q+ K+ + E++ + +Q ++ ++ +EK+ L +
Sbjct: 650 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQ 709
Query: 337 NLEMHDRMEHL 347
+M + EHL
Sbjct: 710 EEKMQEHQEHL 720
Score = 40.8 bits (94), Expect = 0.002
Identities = 41/231 (17%), Positives = 104/231 (45%), Gaps = 12/231 (5%)
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 147
++ IHE+ + + + Q +E +K+RE + + +H QE ++ ++ +
Sbjct: 504 EEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK---EKIHEQEEKIRKQEEKMW 560
Query: 148 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 207
Q + + I E E + + + + + ++ + Q + E+T + ++
Sbjct: 561 RQE-----EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 208 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 267
EQ ++EE EQ+E ++ + ++ E + + K+RE E ++E +
Sbjct: 616 GEQEEKMCEQEEKMQEQEE-KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE- 673
Query: 268 QAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 318
+ EK E+++ EK+ ++ + Q+ ++RQ E++Q + +++
Sbjct: 674 --QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 40.4 bits (93), Expect = 0.003
Identities = 53/267 (19%), Positives = 121/267 (45%), Gaps = 10/267 (3%)
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 147
D+ + EKN +L+ ++Q ++ ++ +Q +++ KL+R L +Q++Q +
Sbjct: 277 DEELKEKNA-KLQEKLQLVESEKSEIQLNVKELKRKLER-AKLLLPQQQLQAEADHLGKE 334
Query: 148 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 207
QS +A + E + N + + + K+QE + + Q E + + +
Sbjct: 335 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ----EEKIREQEEK 390
Query: 208 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 267
+ ++R+E+ + +KE ++ + + E + + + E E + EL +
Sbjct: 391 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 268 QAERE-KAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL 326
+ RE + E+E +EK + + Q+ K+R+ E+++ + + ++ I E
Sbjct: 451 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHE- 509
Query: 327 KEKIAYLE--AENLEMHDRMEHLIEKQ 351
+EKI E E EM + E + E++
Sbjct: 510 QEKIREEEKRQEQEEMWRQEEKIREQE 536
>gi|116812628 coiled-coil domain containing 67 [Homo sapiens]
Length = 604
Score = 60.5 bits (145), Expect = 3e-09
Identities = 67/304 (22%), Positives = 130/304 (42%), Gaps = 39/304 (12%)
Query: 72 DGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDS 131
D E + + +L + + + NQ + + Q Q N ++ ED SS++ R + D
Sbjct: 154 DKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGKKQCLEDSSSEIPRLICDP 213
Query: 132 LHRQEI----QVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAK 187
EI + ++EK + + +NE S R +QD KL +
Sbjct: 214 DPNCEINERDEFIIEK-----------------LKSAVNEIALS-RNKLQDENQKLLQEL 255
Query: 188 RQHQSDCVAFEVTLSRYQREAEQSNVAL---QREEDRVEQKEAEVGELQRRLLGMETEHQ 244
+ +Q C A E LS + E + + L + E ++ ++ ++GE Q
Sbjct: 256 KMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLQLHRELLKIGECQNAQGNKTRLES 315
Query: 245 ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQ 304
+ L ++E E ++EL S D EKE+ +R ++ +++ S+Q ++R
Sbjct: 316 SYLPSIKEPERKIKELFSVMQD-------QPNHEKELNKIRSQLQQVEEYHNSEQERMRN 368
Query: 305 MIEQLQNSKAVIQSKDATIQELKEKIAYLEAE-NLEMHDRMEHLIEKQISHGNFSTQARA 363
I L + K+ TI + +K A LE + +E+ + + L ++++S +
Sbjct: 369 EISDLTEE---LHQKEITIATVTKKAALLEKQLKMELEIKEKMLAKQKVSDMKYKA---V 422
Query: 364 KTEN 367
+TEN
Sbjct: 423 RTEN 426
Score = 34.7 bits (78), Expect = 0.15
Identities = 69/301 (22%), Positives = 124/301 (41%), Gaps = 51/301 (16%)
Query: 86 SGDKMIHEKNINQLKSEV----QYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVL 141
S KM E+ + L++ + Q + A+ CL + +++ L R DSL + + +
Sbjct: 30 SNKKMDWERKMRALETRLDLRDQELANAQTCLDQKGQEVG--LLRQKLDSLEKCNLAMT- 86
Query: 142 EKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTL 201
+ G QS A +S + + E LR Q K+ + H + + FE L
Sbjct: 87 QNYEGQLQSLKAQFSK-------LTNNFEKLRLH-QMKQNKVPRKELPHLKEEIPFE--L 136
Query: 202 SRYQREAEQSNVALQREEDRVE---QKEAEVGELQRRLLG-----METEHQALLAKVREG 253
S ++ E+ A RE D+ E Q + Q++LL + + Q+ ++
Sbjct: 137 SNLNQKLEEFR-AKSREWDKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGK 195
Query: 254 EVALEELRSN--------NADCQAEREKAATLEK------EVAGLREKIHH----LDDML 295
+ LE+ S + +C+ +EK E+A R K+ L L
Sbjct: 196 KQCLEDSSSEIPRLICDPDPNCEINERDEFIIEKLKSAVNEIALSRNKLQDENQKLLQEL 255
Query: 296 KSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHG 355
K QR+ + M L K+ +QS+D + + +E E L++H + + E Q + G
Sbjct: 256 KMYQRQCQAMEAGLSEVKSELQSRD-------DLLRIIEMERLQLHRELLKIGECQNAQG 308
Query: 356 N 356
N
Sbjct: 309 N 309
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 60.1 bits (144), Expect = 3e-09
Identities = 43/169 (25%), Positives = 85/169 (50%), Gaps = 6/169 (3%)
Query: 184 QEAKRQHQSDCVAFEVTLSRYQREA--EQSNVALQREEDRVEQKEAEVGELQRRLLGMET 241
+E KRQ Q D + + R Q E Q ++EE R EQ+E ++ + + ++ E
Sbjct: 561 EEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE-KMWKQEEKIREQEE 619
Query: 242 EHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRK 301
+ Q K+RE E E++R Q + EK E+++ EK+ ++ + Q+ K
Sbjct: 620 KIQEQEEKIREQE---EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEK 676
Query: 302 VRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 350
+R+ ++++ + I+ ++ +QE +EK+ E + E ++M+ EK
Sbjct: 677 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Score = 48.9 bits (115), Expect = 8e-06
Identities = 37/168 (22%), Positives = 81/168 (48%), Gaps = 7/168 (4%)
Query: 184 QEAKRQHQSDCVAFEVTLS------RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLL 237
+E KRQ Q + E + R + + + ++++E++V ++E ++ E + ++
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR 527
Query: 238 GMETEHQALLAKVREGE-VALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLK 296
E + K+RE E + EE + + + E EK E ++ EKI ++ +
Sbjct: 528 EQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Query: 297 SQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRM 344
Q+ K+R+ E+ Q + + ++ I+E +EKI E + E +++
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKI 635
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/162 (19%), Positives = 76/162 (46%), Gaps = 9/162 (5%)
Query: 184 QEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 243
QE KRQ Q E + + + + + +Q +E+++ ++E ++ E + E +
Sbjct: 596 QEEKRQEQ------EEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKM 649
Query: 244 QALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVR 303
K+ E E E+++ + EK EK++ EKI ++M++ Q+ K+
Sbjct: 650 GEQEEKMCEQE---EKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 706
Query: 304 QMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRME 345
+ E++ + +Q ++ ++ +EK+ E + ++M+
Sbjct: 707 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Score = 48.5 bits (114), Expect = 1e-05
Identities = 68/350 (19%), Positives = 138/350 (39%), Gaps = 49/350 (14%)
Query: 44 QKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEV 103
+K T ++ HS E SH H+E ++ L+ + I +L+ +
Sbjct: 88 KKINNGTNPETTTSGGCHSPEDEQKASHQ-HQEALRRELEAQVHTIRILTCQKTELQMAL 146
Query: 104 QYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDT 163
Y Q A L+ D+ S+L + + Q+ +A+ + + D
Sbjct: 147 YYSQHAVKQLEGEARDLISRLHDSW-------------KFAGELEQALSAVATQKKKADR 193
Query: 164 CINE--------DVESLRKTVQD-----LLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 210
I E +E R T+ D AKLQE + +S+ ++ + +R+ E+
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEV--------------A 256
+ + L ++ Q +AE L + L + + QA +V E E+
Sbjct: 254 AKLLLPQQ-----QLQAEADHLGKELQSVSAKLQA---QVEENELWNRLNQQQEEKMWRQ 305
Query: 257 LEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVI 316
E+++ Q + EK E+++ EK+ ++M+ ++ K+R+ E + + +
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 317 QSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTE 366
+ ++ + E +EK+ E E +++ L EK Q + E
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 415
Score = 46.6 bits (109), Expect = 4e-05
Identities = 60/321 (18%), Positives = 136/321 (42%), Gaps = 39/321 (12%)
Query: 31 QGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKM 90
Q + D L Q K A V + + L + E EE I+ + ++
Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEW------EEK 315
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQS 150
I E+ +++ + + I+E +++ E + K ++ + RQE +++ EK +
Sbjct: 316 IQEQE-EKIREQEEKIREQEEKMRRQEEMMWEKEEK-----MRRQE-EMMWEKEEKMRRQ 368
Query: 151 PTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 210
++ ++ E + + +++L K+ E ++ + + E R Q + ++
Sbjct: 369 EEMMWEKEEKMRRQ-EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 427
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAE 270
+ R+E+++ ++E ++ E ++++ E K+ E E EE + +
Sbjct: 428 QEAKMWRQEEKIREQEEKIREQEKKMWRQEE-------KIHEQEKIREEEKRQEQEEMWR 480
Query: 271 REKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI 330
+E+ ++E+ +EK+H ++ ++ Q+ KV + E+ I+E +EKI
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEK--------------IREQEEKI 526
Query: 331 AYLEAENLEMHDRMEHLIEKQ 351
E E R E I +Q
Sbjct: 527 ----REQEEKMWRQEEKIREQ 543
Score = 46.6 bits (109), Expect = 4e-05
Identities = 47/268 (17%), Positives = 126/268 (47%), Gaps = 20/268 (7%)
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPNGFS 148
++++ ++ + + IQE +Q+ E I + + R + + RQE +++ EK
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE-EMMWEKEEKMR 352
Query: 149 QSPTALYSSPPEV---DTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQ 205
+ ++ ++ + + E E +R+ ++++ + +E R+ + E + +
Sbjct: 353 RQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-EEMMWEKEEKIRELEEKMHEQEKIREQEE 411
Query: 206 REAEQSNVALQREEDRVEQKEA-------EVGELQRRLLGMETEHQALLAKVREGEVALE 258
+ E+ + RE+++ +++EA ++ E + ++ E + K+ E E E
Sbjct: 412 KRQEEEKI---REQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 259 ELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 318
E + + +E+ ++E+ +EK+H ++ ++ Q+ KV + E+++ + I+
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 319 KDATIQELKEKIAYLE---AENLEMHDR 343
++ + +EKI E E +MH++
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Score = 45.1 bits (105), Expect = 1e-04
Identities = 53/285 (18%), Positives = 127/285 (44%), Gaps = 24/285 (8%)
Query: 83 KGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVV 140
K R ++M+ EK +++ + + + E +++ E + K + R L + +H QE ++
Sbjct: 350 KMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE-KIR 407
Query: 141 LEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVT 200
++ + E + + E +R+ Q+ + QE K Q + + +
Sbjct: 408 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE--QEEKIREQEKKMWRQEEKIHEQEK 465
Query: 201 LSRYQREAEQSNVALQ-----------REEDRVEQKEAEVGELQRRLLGMETEHQALLAK 249
+ ++ EQ + Q R+++++ ++E ++ + + ++ E + + K
Sbjct: 466 IREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK 525
Query: 250 VREGEVAL----EELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQM 305
+RE E + E++R + RE+ E+E EK +D + Q+ K+R+
Sbjct: 526 IREQEEKMWRQEEKIREQE---EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ 582
Query: 306 IEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEK 350
E++ + I+ ++ QE +EK+ E + E ++++ EK
Sbjct: 583 EEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Score = 38.5 bits (88), Expect = 0.010
Identities = 28/141 (19%), Positives = 67/141 (47%), Gaps = 4/141 (2%)
Query: 170 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 229
E +R+ + + + ++ + Q + E+T + ++ EQ ++EE EQ+E +
Sbjct: 612 EKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET-M 670
Query: 230 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 289
+ ++ E + + K+RE E ++E + + EK E+++ EK+
Sbjct: 671 WRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE---QEEKMCEQEEKMQEQEEKMR 727
Query: 290 HLDDMLKSQQRKVRQMIEQLQ 310
++ + Q+ ++RQ E++Q
Sbjct: 728 RQEEKMWEQEVRLRQQEEKMQ 748
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 59.3 bits (142), Expect = 6e-09
Identities = 78/345 (22%), Positives = 155/345 (44%), Gaps = 30/345 (8%)
Query: 24 DILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHS--LASELVESHDGHEEIIKVY 81
+ILRL Q E + L QKA + A + + L +++ S E+ I+
Sbjct: 632 EILRLHQQKEQSLSSLRERLQKAIEEEEARMREEESQRLSWLRAQVQSSTQADEDQIRAE 691
Query: 82 LKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI--SSKLDRNLGDSLHRQEIQV 139
+ S K+ E Q Q+ R L++L+E+I S K ++ ++ + +Q
Sbjct: 692 QEA-SLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEASEKSEQAALNAAKEKALQQ 750
Query: 140 VLEKPNGFSQSPTALYSSP--PEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAF 197
+ E+ G + A E++ + R+ V L K+QEA+++ ++
Sbjct: 751 LREQLEGERKEAVATLEKEHSAELERLCSSLEAKHREVVSSLQKKIQEAQQKEEAQ---L 807
Query: 198 EVTLSRYQREAEQSNVALQREEDRV-----EQKEAEVGELQRRLLGMETEHQALLAKVRE 252
+ L + + Q + + E + E+++ GE +RRL M+ EHQ ++AK RE
Sbjct: 808 QKCLGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKARE 867
Query: 253 GEVALEELRSNNADC------QAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMI 306
A E R A+ + ER + A E+E+ +R++ H L+ +R+ R+
Sbjct: 868 QYEA--EERKQRAELLGHLTGELERLQRAH-ERELETVRQEQH---KRLEDLRRRHREQE 921
Query: 307 EQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQ 351
+LQ+ + ++++ +++K ++A LE + + L++ Q
Sbjct: 922 RKLQDLELDLETR---AKDVKARLALLEVQEETARREKQQLLDVQ 963
Score = 37.0 bits (84), Expect = 0.031
Identities = 75/380 (19%), Positives = 146/380 (38%), Gaps = 60/380 (15%)
Query: 39 LEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQ 98
L + + +K+Y + SL E + +G E R DKM E
Sbjct: 811 LGQVEHRVHQKSYHVAGYEHELSSLLREKRQEVEGEHE--------RRLDKMKEEHQQVM 862
Query: 99 LKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSP 158
K+ QY E R +L ++ +L+R H +E++ V ++ +
Sbjct: 863 AKAREQYEAEERKQRAELLGHLTGELERL--QRAHERELETVRQEQH------------- 907
Query: 159 PEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQRE 218
++ E RK +QDL L+ + ++ EV +RE +Q + +QR+
Sbjct: 908 KRLEDLRRRHREQERK-LQDLELDLETRAKDVKARLALLEVQEETARREKQQL-LDVQRQ 965
Query: 219 EDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLE 278
V K E ++L + EH LL ++ L+EL++ +++ + L+
Sbjct: 966 ---VALKSEEATATHQQLEEAQKEHTHLLQSNQQLREILDELQARKLKLESQVD---LLQ 1019
Query: 279 KEVAGLREKIHHLDDMLKSQQRKVRQM----------------IEQLQNSKAVIQSKD-- 320
+ L++ L+ + +Q +R++ IE L+ S Q+K+
Sbjct: 1020 AQSQQLQKHFSSLEAEAQKKQHLLREVTVEENNASPHFEPDLHIEDLRKSLGTNQTKEVS 1079
Query: 321 ATIQELKEKI-----------AYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPG 369
+++ + KE + L AE + + E L+++ S T +A ++
Sbjct: 1080 SSLSQSKEDLYLDSLSSHNVWHLLSAEGVALRSAKEFLVQQTRSMRRRQTALKAAQQHWR 1139
Query: 370 SIRISKPPSPKPMPVIRVVE 389
S K P I+ +E
Sbjct: 1140 HELASAQEVAKDPPGIKALE 1159
Score = 36.6 bits (83), Expect = 0.040
Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 24/199 (12%)
Query: 167 EDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKE 226
ED + + + +L +K + + S + E R Q E + E KE
Sbjct: 447 EDKDDSQSSQDELQSKQSKGLEERLSPPLPHEERAQSPPRSLATEEEPPQGPEGQPEWKE 506
Query: 227 AE-VGELQRRLLGMETEHQ--------ALLAKVREGEVALEELRSNNADCQAEREKAAT- 276
AE +GE L ++ Q A K +E EEL + + EK A
Sbjct: 507 AEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVS 566
Query: 277 ----LEKEVAGLR-----EKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELK 327
+ EV E++ + LK+ + V Q++EQ Q + +++SK +Q+L+
Sbjct: 567 PTPPVSPEVRSTEPVAPPEQLS--EAALKAMEEAVAQVLEQDQ--RHLLESKQEKMQQLR 622
Query: 328 EKIAYLEAEN-LEMHDRME 345
EK+ E E L +H + E
Sbjct: 623 EKLCQEEEEEILRLHQQKE 641
>gi|4503593 epidermal growth factor receptor pathway substrate 15
isoform A [Homo sapiens]
Length = 896
Score = 58.9 bits (141), Expect = 7e-09
Identities = 45/204 (22%), Positives = 101/204 (49%), Gaps = 19/204 (9%)
Query: 145 NGFSQSPTALYSSPPEVDTCINE--DVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLS 202
N SP A +S+ E+DT NE D++ + V+ L + ++ +Q S+ +
Sbjct: 319 NIIGSSPVADFSAIKELDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSE-------VQ 371
Query: 203 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRS 262
Q E ++ N LQ+ + + +Q + + EL + +E + + + K E + L+
Sbjct: 372 DLQDEVQRENTNLQKLQAQKQQVQELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLK- 430
Query: 263 NNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDAT 322
A+ ++ + +T E+E+A RE++ L Q++ ++ E +++ KA ++
Sbjct: 431 --AELTSQESQISTYEEELAKAREELSRL-------QQETAELEESVESGKAQLEPLQQH 481
Query: 323 IQELKEKIAYLEAENLEMHDRMEH 346
+Q+ +++I+ ++ + +EM D H
Sbjct: 482 LQDSQQEISSMQMKLMEMKDLENH 505
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 58.9 bits (141), Expect = 7e-09
Identities = 81/388 (20%), Positives = 165/388 (42%), Gaps = 66/388 (17%)
Query: 24 DILRLTLQGELTGDELEHIAQKAGRKTYAMV----SSHSAGHSLASELVESHDGHEEIIK 79
+++R T Q + + + QK + T + ++ SA SL ++ E +E +
Sbjct: 342 ELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELS 401
Query: 80 -------------VYLKGRSGDKMIHEKNI-NQLKSEVQYIQEARNCLQKLREDISSKLD 125
+ +K R ++ KN+ N L++E+ + + L+ E+ KL
Sbjct: 402 RQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLC 461
Query: 126 RN----LGDSLHRQEIQVVLE---KPNGFSQSPTA--------LYSSPPEVDTCIN---- 166
R + E++ +E K N +S + L + + C+N
Sbjct: 462 RAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQN 521
Query: 167 --EDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQ 224
E++++ + + +L LQE Q ++ ++ L+ E ++ +D +++
Sbjct: 522 FAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDC-----SQDLLKK 576
Query: 225 KEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNA--DC-QAEREKAAT-LEKE 280
+E + +L +L E E +ALL+ + + EEL+ C ++E EK T +E E
Sbjct: 577 REHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESE 636
Query: 281 VAGLREKIHHLDDMLKSQQRKVRQMIE--------------QLQNSKAVIQSKDATIQEL 326
L+ KI+HL+ LK+QQ K + E +++N V+ SK ++
Sbjct: 637 KENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVE-- 694
Query: 327 KEKIAYLEAENLEMHDRMEHLIEKQISH 354
+K+AY+E + +H +K+I +
Sbjct: 695 TQKLAYMELQQKAEFSDQKH--QKEIEN 720
Score = 52.0 bits (123), Expect = 9e-07
Identities = 57/268 (21%), Positives = 116/268 (43%), Gaps = 24/268 (8%)
Query: 97 NQLKSEVQYIQEARNCLQKLREDISSK---LDRNLGDSLHRQEI-QVVLEKPNGFSQSPT 152
NQL+ E+ + + L +L E + K L+ + + LH ++ + +++ Q+ +
Sbjct: 1961 NQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLS 2020
Query: 153 ALYSSPPEVDTCINEDVESLRKTVQDL----------LAKLQEAKRQHQSDCVAFEVTLS 202
+ S + T + E ++SL K Q L +A+L + K + + + LS
Sbjct: 2021 SDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLS 2080
Query: 203 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRS 262
+ + E+ NV+ E VE+ GE RL + E L + + V +E
Sbjct: 2081 --ESDYEKLNVSKALEAALVEK-----GEFALRLSSTQEEVHQLRRGIEKLRVRIEADEK 2133
Query: 263 NNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDAT 322
EK E+E L++K+ +L+ L+ + +I +NSKA +++
Sbjct: 2134 KQLHIA---EKLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQ 2190
Query: 323 IQELKEKIAYLEAENLEMHDRMEHLIEK 350
I+E+ + E + + + E+L ++
Sbjct: 2191 IEEMARSLKVFELDLVTLRSEKENLTKQ 2218
Score = 49.3 bits (116), Expect = 6e-06
Identities = 71/344 (20%), Positives = 152/344 (44%), Gaps = 45/344 (13%)
Query: 16 EDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHE 75
E+Q +D + E ++E +A+ +V+ S +L ++ E
Sbjct: 2168 ENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLS 2227
Query: 76 EIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQ 135
E+ K+ +S ++ EK ++E+Q +E++ ++ L+ + +L+ + Q
Sbjct: 2228 ELDKLLSSFKS---LLEEKE----QAEIQIKEESKTAVEMLQNQLK-ELNEAVAALCGDQ 2279
Query: 136 EIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQ----DLLAKLQEAKR-QH 190
EI E+ S P P E + + +E LR ++ L LQ+ K +H
Sbjct: 2280 EIMKATEQ----SLDP------PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEH 2329
Query: 191 QSDCVAFEVTLSRYQREAE-----QSNVALQREEDR--VEQKEAEVGELQRRLLGME--- 240
+D + V +RE E Q + AL+ E + VE +A++ + + L G+E
Sbjct: 2330 HADLLKGRV--ENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDV 2387
Query: 241 ----TEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLK 296
+E + L ++++ + + EL N+ + ++ E+E ++EK +ML+
Sbjct: 2388 VTIRSEKENLTNELQKEQERISELEIINSSFENILQEK---EQEKVQMKEKSSTAMEMLQ 2444
Query: 297 SQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 340
+Q +++ + + L N + ++K+ Q L ++ LE E ++
Sbjct: 2445 TQLKELNERVAALHNDQEACKAKE---QNLSSQVECLELEKAQL 2485
Score = 48.5 bits (114), Expect = 1e-05
Identities = 56/279 (20%), Positives = 116/279 (41%), Gaps = 37/279 (13%)
Query: 97 NQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKP---NGFSQSPTA 153
N++ + + Q+ + LR+ + SK + + H++ + ++P + F+
Sbjct: 744 NEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGE 803
Query: 154 LYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNV 213
S P E C E +S + + A Q++ D + F + +Q N
Sbjct: 804 QGSMPSERSECRLEADQSPKNS----------AILQNRVDSLEFSL------ESQKQMNS 847
Query: 214 ALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEE-------------- 259
LQ++ + + Q + GE++ L+ E HQ+ +A+ + L+E
Sbjct: 848 DLQKQCEELVQIK---GEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLS 904
Query: 260 -LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 318
L + + Q +K T + E+ L++ H L+D LK Q + + + ++I
Sbjct: 905 ALENKEKELQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISL 964
Query: 319 KDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNF 357
I+EL ++ L+ N ++ +LI+K S N+
Sbjct: 965 NKREIEELTQENGTLKEINASLNQEKMNLIQKSESFANY 1003
Score = 45.4 bits (106), Expect = 9e-05
Identities = 79/387 (20%), Positives = 168/387 (43%), Gaps = 60/387 (15%)
Query: 38 ELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNIN 97
EL ++ + +K + S +++ L S+ E +++ DKM + +N
Sbjct: 2557 ELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELEL----TKMDKMSFVEKVN 2612
Query: 98 QLKS-EVQYIQEARNCLQK---LREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTA 153
++ + E + +E QK L+E++S + +R G E+Q++LE+
Sbjct: 2613 KMTAKETELQREMHEMAQKTAELQEELSGEKNRLAG------ELQLLLEEIKSSKDQLKE 2666
Query: 154 LYSSPPEVDT---CINED-VES---LRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQR 206
L E+ C+++D VE +R+ + + +L EA+++HQ+ + T +Y+
Sbjct: 2667 LTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLD---TNKQYEV 2723
Query: 207 EAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNAD 266
E + L +E+ + ++ E+ L+ + + L ++ LEEL+ D
Sbjct: 2724 EIQTYREKLTSKEECLSSQKLEIDLLK-------SSKEELNNSLKATTQILEELKKTKMD 2776
Query: 267 -------CQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSK 319
+ E E+A K + +++ ++L+ + ++ Q ++ Q + V+ +K
Sbjct: 2777 NLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQL-QAAQEKQKTGTVMDTK 2835
Query: 320 -DATIQELKEKIAYLEAENLE-------------MHDRME---HLIEKQISHGNFSTQAR 362
D E+KE LE + E H+++E ++E Q++H +
Sbjct: 2836 VDELTTEIKELKETLEEKTKEADEYLDKYCSLLISHEKLEKAKEMLETQVAH---LCSQQ 2892
Query: 363 AKTENPGSIRISKPPSPKPMPVIRVVE 389
+K ++ GS + P P P P+ V E
Sbjct: 2893 SKQDSRGSPLLG-PVVPGPSPIPSVTE 2918
Score = 33.5 bits (75), Expect = 0.34
Identities = 59/319 (18%), Positives = 129/319 (40%), Gaps = 42/319 (13%)
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 147
D +H + + QL ++++ E + +L+++ S ++ S QE+ +E G
Sbjct: 1808 DSKLHLQEV-QLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGL 1866
Query: 148 SQSPTALYSSPPEVD-----TCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLS 202
+ D +N+ + V++ L++++ K + + + E L
Sbjct: 1867 NSDLEMHADKSSREDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEADLE 1926
Query: 203 RYQREA---EQSNVALQRE----EDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEV 255
Q E E+ N Q+ E+ + +E +L+ L M + AL + +
Sbjct: 1927 VVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKE 1986
Query: 256 ALEELRSNNADC-----------QAEREKAATLEKEVAGLREKIHHLDDMLKSQQR---- 300
+EL S+ ++C + + E TL +V+ L + HL + L+S ++
Sbjct: 1987 KTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQA 2046
Query: 301 ------KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRME-HLIEKQIS 353
++ I QL K ++ + + L+ +++ + E L + +E L+EK
Sbjct: 2047 LSLTKCELENQIAQLNKEKELLVKES---ESLQARLSESDYEKLNVSKALEAALVEK--- 2100
Query: 354 HGNFSTQARAKTENPGSIR 372
G F+ + + E +R
Sbjct: 2101 -GEFALRLSSTQEEVHQLR 2118
Score = 30.4 bits (67), Expect = 2.9
Identities = 63/328 (19%), Positives = 128/328 (39%), Gaps = 67/328 (20%)
Query: 76 EIIKVYLKGRSGDKMIHEKN-INQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHR 134
E ++ L+ D + K+ LK E+ ++E +N +QK D+ + ++ + +
Sbjct: 1104 ETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTK 1163
Query: 135 QEIQVVLEKPNGFS----QSPTALYSSPPEVDTCINE--------DVESLRKTVQDLLAK 182
E Q + +P S +S + P++D + E + L +++ K
Sbjct: 1164 HECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELK 1223
Query: 183 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLG---- 238
LQE++++ +C+ E L + + E SN+ + ++ K+ E+ ++ + G
Sbjct: 1224 LQESEKE--KECLQHE--LQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEKYISGPHEL 1279
Query: 239 ---------METEHQALLAKVREGEVALE-----------ELRSNNADCQAEREKAATLE 278
++ Q + K+ E E E EL + ++C K A
Sbjct: 1280 STSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMA--- 1336
Query: 279 KEVAGLREKIHHLDD-------------------MLKSQQRKVRQMIEQLQNSKAVIQSK 319
+EV L ++ L+D ++Q V NS +
Sbjct: 1337 EEVGKLLNEVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLS 1396
Query: 320 DATIQ----ELKEKIAYLEAENLEMHDR 343
D +Q EL+EK L++E+ +HD+
Sbjct: 1397 DKEVQMHFAELQEKFLSLQSEHKILHDQ 1424
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 58.9 bits (141), Expect = 7e-09
Identities = 70/362 (19%), Positives = 156/362 (43%), Gaps = 44/362 (12%)
Query: 11 VDVHPEDQAAGSVDILRLTLQGELTGDELEHIAQ----------KAGRKTYAMVSSHSAG 60
+D + E+ + +I+ L GE ++ H++Q + +KT A+
Sbjct: 992 MDQYKEELSKMEKEIMHLKRDGE---NKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQ 1048
Query: 61 HSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDI 120
HS +EL E+ E+++ L+ G+ LKS ++ +QE R+ LQK + +
Sbjct: 1049 HSTETELTEALQ-KREVLETELQNAHGE----------LKSTLRQLQELRDVLQKAQLSL 1097
Query: 121 SSKLDRNLGDSLHRQEIQVVLE-KPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDL 179
K + +E ++ +E K + AL N +++ V L
Sbjct: 1098 EEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKER--------NWELKQRAAQVTHL 1149
Query: 180 LAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGM 239
++E + + + + E TL + + E ++ N ++ D+++ + ++ E + +L
Sbjct: 1150 DMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQN 1209
Query: 240 ETEHQALLAKVREGEVALEELRSNNADCQ----AEREKAATLEKEVAGLREKIHHLDDML 295
E E L ++ + ++E+ S + + + ++A L +E+ RE++ + L
Sbjct: 1210 EQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTEL 1269
Query: 296 KSQ-------QRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLI 348
QR++ ++ +L++ K + + KDA L E++ + + RM+ I
Sbjct: 1270 AEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEI 1329
Query: 349 EK 350
+K
Sbjct: 1330 KK 1331
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/245 (21%), Positives = 105/245 (42%), Gaps = 33/245 (13%)
Query: 106 IQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCI 165
+ E+R + KL ++ +K D + R + ++ E + + + +D C
Sbjct: 451 LTESRQSILKLESELENK------DEILRDKFSLMNEN----RELKVRVAAQNERLDLC- 499
Query: 166 NEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRV--- 222
+++ES R ++ L + + + + F+ LS+YQ + +EDR
Sbjct: 500 QQEIESSRVELRSLEKIISQLPLKRE--LFGFKSYLSKYQMSS------FSNKEDRCIGC 551
Query: 223 -EQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEV 281
E + + EL+ +L E E Q L A + +++ + N++ E K ++LE E
Sbjct: 552 CEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQ---ESSKLSSLETEP 608
Query: 282 AGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMH 341
L H + + +K Q + + + + V I+EL+ K+ +EAEN ++
Sbjct: 609 VKLGG--HQVAESVKDQNQHTMNKQYEKERQRLV-----TGIEELRTKLIQIEAENSDLK 661
Query: 342 DRMEH 346
M H
Sbjct: 662 VNMAH 666
Score = 43.9 bits (102), Expect = 2e-04
Identities = 50/258 (19%), Positives = 113/258 (43%), Gaps = 22/258 (8%)
Query: 98 QLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLE--------KPNGFSQ 149
Q+K E+ +E L K+ ++I ++H ++ ++L+ K N +
Sbjct: 987 QVKIEMDQYKEE---LSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKE 1043
Query: 150 SPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAE 209
+S+ E+ + + E L +Q+ +L+ RQ Q L + Q E
Sbjct: 1044 LEKLQHSTETELTEALQKR-EVLETELQNAHGELKSTLRQLQE----LRDVLQKAQLSLE 1098
Query: 210 QSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQA 269
+ ++ + + + E+ + ++ LL M+ QAL K R E+ + + D
Sbjct: 1099 EKYTTIKDLTAELRECKMEIEDKKQELLEMD---QAL--KERNWELKQRAAQVTHLDMTI 1153
Query: 270 EREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEK 329
RE +E+++ L + + LK +++ + ++LQN+K ++ K+ + + +++
Sbjct: 1154 -REHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQE 1212
Query: 330 IAYLEAENLEMHDRMEHL 347
I+ L+ E RM+ +
Sbjct: 1213 ISQLKKEIERTQQRMKEM 1230
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/121 (20%), Positives = 67/121 (55%), Gaps = 4/121 (3%)
Query: 219 EDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLE 278
+ ++ ++ +L+++ + T++ +L+ K L + R+ + ++ +++AA+
Sbjct: 228 DQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAAS-- 285
Query: 279 KEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENL 338
V L E+I +L+ + +Q + +R+ +L+ S+ ++ K+ ++QE KE+ L+ + L
Sbjct: 286 --VPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLL 343
Query: 339 E 339
E
Sbjct: 344 E 344
Score = 37.0 bits (84), Expect = 0.031
Identities = 74/350 (21%), Positives = 139/350 (39%), Gaps = 32/350 (9%)
Query: 36 GDELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDG------HEEIIKVYLKGRSGDK 89
G+EL ++ YA S S L ++ SH G +E + K+ K
Sbjct: 158 GEELSSVSPSEN-SDYAPNPSRS--EKLILDVQPSHPGLLNYSPYENVCKISGSSTDFQK 214
Query: 90 MIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLG-----DSLHRQEIQVVLEKP 144
+K + Q I+ R L KLR+ + + +N +S+H E+ K
Sbjct: 215 KPRDKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHF-ELTQSRAKV 273
Query: 145 NGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRY 204
+ + S P + IN + E + QD + + E K + V + +
Sbjct: 274 SMLESAQQQAASVPILEEQIINLEAEV---SAQDKVLREAENKLEQSQKMV-----IEKE 325
Query: 205 QREAEQSNVALQREEDRVEQ-KEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSN 263
Q E ++ + D +EQ K+ + E QR E + + + +VA E+L
Sbjct: 326 QSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVA-EKLEKV 384
Query: 264 NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSK-----AVIQS 318
A+ + EKE L+E+ L+ + K+RQ+ E+ N K +++
Sbjct: 385 QAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKN 444
Query: 319 KDATIQELKEKIAYLEAENLEMHDRMEHLIEK-QISHGNFSTQARAKTEN 367
+ Q + + + L+ E+ E+ ++ E L +K + + N + R +N
Sbjct: 445 SEVMAQLTESRQSILKLES-ELENKDEILRDKFSLMNENRELKVRVAAQN 493
Score = 36.6 bits (83), Expect = 0.040
Identities = 55/274 (20%), Positives = 124/274 (45%), Gaps = 39/274 (14%)
Query: 95 NINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTAL 154
N+ S+ Q IQE L+K SSKL+ + + + LEK +
Sbjct: 663 NMAHRTSQFQLIQE--ELLEKASN--SSKLESEMTKKCSQL---LTLEKQ---LEEKIVA 712
Query: 155 YSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFE----VTLSRY---QRE 207
YSS + + +++ + ++ L + +H+ C+AFE + L ++ +++
Sbjct: 713 YSSIAAKNAELEQELMEKNEKIRSLETNINT---EHEKICLAFEKAKKIHLEQHKEMEKQ 769
Query: 208 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQAL--LAKVREGEVALEELRSNNA 265
E+ L++++ + +++E + LQ+ ++ + ++L L +GE+ E ++ +
Sbjct: 770 IERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKD-- 827
Query: 266 DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSK----AVIQSKDA 321
E L+ +V+ K+ LD L+ + ++ + QL+ +K ++ K
Sbjct: 828 ------EALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSE 881
Query: 322 TI----QELKEKIAYLEAENLEMHDRMEHLIEKQ 351
+ +ELK K L+ E E + ++H +++Q
Sbjct: 882 EVYCLQKELKIKNHSLQ-ETSEQNVILQHTLQQQ 914
Score = 32.0 bits (71), Expect = 0.98
Identities = 36/154 (23%), Positives = 67/154 (43%), Gaps = 18/154 (11%)
Query: 203 RYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRS 262
+Y++E ++ ++ ++ Q EAE +L+ + ++ Q + + L E S
Sbjct: 631 QYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLI-------QEELLEKAS 683
Query: 263 NNADCQAEREKAA----TLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS 318
N++ ++E K TLEK+ L EKI S K ++ ++L I+S
Sbjct: 684 NSSKLESEMTKKCSQLLTLEKQ---LEEKIV----AYSSIAAKNAELEQELMEKNEKIRS 736
Query: 319 KDATIQELKEKIAYLEAENLEMHDRMEHLIEKQI 352
+ I EKI + ++H +EKQI
Sbjct: 737 LETNINTEHEKICLAFEKAKKIHLEQHKEMEKQI 770
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/344 (19%), Positives = 149/344 (43%), Gaps = 37/344 (10%)
Query: 40 EHIAQKAGRKTYAMVSSHSA-GHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQ 98
E QK + Y S SL S+L ++ + ++I ++ H++ + +
Sbjct: 535 EETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEE 594
Query: 99 LK--------SEVQYIQEARNCLQKLREDISSKLD--RNLGDS---LHRQEIQ------- 138
LK +E E + ++K+R D +++ +N DS H +E++
Sbjct: 595 LKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLM 654
Query: 139 -VVLEKPNGFSQSPTALYSSPP----EVDTCIN--EDVESLRKTVQDLLAKLQEAKRQHQ 191
V+ EK N + L + E++ +N ++ E K ++ L AK E +
Sbjct: 655 KVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVID 714
Query: 192 SDCVAFEVT------LSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQA 245
+ + T L ++ + + +++ ++E E ++ L+ ++ +
Sbjct: 715 NFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASS 774
Query: 246 LLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQM 305
+ +++ E+ L L+ N ++ +E TLEKE+ L+EK + S QR +++
Sbjct: 775 ITRELQGRELKLTNLQENLSEVSQVKE---TLEKELQILKEKFAEASEEAVSVQRSMQET 831
Query: 306 IEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 349
+ +L + + +++L+E +A +EA+ E +R E LI+
Sbjct: 832 VNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIK 875
Score = 53.5 bits (127), Expect = 3e-07
Identities = 66/326 (20%), Positives = 140/326 (42%), Gaps = 34/326 (10%)
Query: 44 QKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEV 103
+K R+ + + + +A + S D ++ K+ + + + E+++ +L+ ++
Sbjct: 865 EKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKM-----NDELRLKERDVEELQLKL 919
Query: 104 QYIQEARNCLQKLREDISSKLDRNLGDSLHRQE------------IQVVLEKPNGFSQSP 151
E + LQK ED++ K +++ ++ + E ++ +E + Q
Sbjct: 920 TKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQEL 979
Query: 152 TALYS-SPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 210
A Y + E T E +++L+KT+ D KL+ A+ ++ L +++A++
Sbjct: 980 KARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSG----LLQELEELRKQADK 1035
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQAL------LAKVREGEVA-LEELRSN 263
+ A Q ED ++ E E L +E Q L ++E + +EEL +
Sbjct: 1036 AKAA-QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKS 1094
Query: 264 NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATI 323
E +K KE+ L++ L + Q + ++ E+L S+ + S
Sbjct: 1095 KELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSH---- 1150
Query: 324 QELKEKIAYLEAENLEMHDRMEHLIE 349
Q+L+E+ + L + LEM R I+
Sbjct: 1151 QKLEEERSVLNNQLLEMKKRESKFIK 1176
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/318 (18%), Positives = 121/318 (38%), Gaps = 62/318 (19%)
Query: 92 HEKNINQLKS-----------EVQYIQEARNCLQKLREDISSKLDRNLGDS-----LHRQ 135
H++ I LK E++ + A L K E + SKL+ ++ L +
Sbjct: 520 HQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKS 579
Query: 136 EIQVVLEKPNGFSQSPTALYSSPPEVDTC----INEDVESLRKTVQDLLAKLQEA----K 187
+++ + + +S +T + +E +R Q + LQ +
Sbjct: 580 KLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSER 639
Query: 188 RQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK-------------EAEVGELQR 234
H + A L + +E E S A++ + D+ E + EAE+ +
Sbjct: 640 AAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKEL 699
Query: 235 RLLGMETEHQ--------ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLRE 286
+L + Q + L E + L+ LR +++ ++E +K L +++ +
Sbjct: 700 EVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKK---LRQQLEAAEK 756
Query: 287 KIHHLD--------------DMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAY 332
+I HL+ L+ ++ K+ + E L V ++ + +Q LKEK A
Sbjct: 757 QIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAE 816
Query: 333 LEAENLEMHDRMEHLIEK 350
E + + M+ + K
Sbjct: 817 ASEEAVSVQRSMQETVNK 834
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/344 (19%), Positives = 149/344 (43%), Gaps = 37/344 (10%)
Query: 40 EHIAQKAGRKTYAMVSSHSA-GHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQ 98
E QK + Y S SL S+L ++ + ++I ++ H++ + +
Sbjct: 570 EETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEE 629
Query: 99 LK--------SEVQYIQEARNCLQKLREDISSKLD--RNLGDS---LHRQEIQ------- 138
LK +E E + ++K+R D +++ +N DS H +E++
Sbjct: 630 LKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLM 689
Query: 139 -VVLEKPNGFSQSPTALYSSPP----EVDTCIN--EDVESLRKTVQDLLAKLQEAKRQHQ 191
V+ EK N + L + E++ +N ++ E K ++ L AK E +
Sbjct: 690 KVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVID 749
Query: 192 SDCVAFEVT------LSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQA 245
+ + T L ++ + + +++ ++E E ++ L+ ++ +
Sbjct: 750 NFTSQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASS 809
Query: 246 LLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQM 305
+ +++ E+ L L+ N ++ +E TLEKE+ L+EK + S QR +++
Sbjct: 810 ITRELQGRELKLTNLQENLSEVSQVKE---TLEKELQILKEKFAEASEEAVSVQRSMQET 866
Query: 306 IEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIE 349
+ +L + + +++L+E +A +EA+ E +R E LI+
Sbjct: 867 VNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIK 910
Score = 53.5 bits (127), Expect = 3e-07
Identities = 66/326 (20%), Positives = 140/326 (42%), Gaps = 34/326 (10%)
Query: 44 QKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEV 103
+K R+ + + + +A + S D ++ K+ + + + E+++ +L+ ++
Sbjct: 900 EKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKM-----NDELRLKERDVEELQLKL 954
Query: 104 QYIQEARNCLQKLREDISSKLDRNLGDSLHRQE------------IQVVLEKPNGFSQSP 151
E + LQK ED++ K +++ ++ + E ++ +E + Q
Sbjct: 955 TKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQEL 1014
Query: 152 TALYS-SPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 210
A Y + E T E +++L+KT+ D KL+ A+ ++ L +++A++
Sbjct: 1015 KARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSG----LLQELEELRKQADK 1070
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQAL------LAKVREGEVA-LEELRSN 263
+ A Q ED ++ E E L +E Q L ++E + +EEL +
Sbjct: 1071 AKAA-QTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKS 1129
Query: 264 NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATI 323
E +K KE+ L++ L + Q + ++ E+L S+ + S
Sbjct: 1130 KELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSH---- 1185
Query: 324 QELKEKIAYLEAENLEMHDRMEHLIE 349
Q+L+E+ + L + LEM R I+
Sbjct: 1186 QKLEEERSVLNNQLLEMKKRESKFIK 1211
Score = 40.4 bits (93), Expect = 0.003
Identities = 59/318 (18%), Positives = 121/318 (38%), Gaps = 62/318 (19%)
Query: 92 HEKNINQLKS-----------EVQYIQEARNCLQKLREDISSKLDRNLGDS-----LHRQ 135
H++ I LK E++ + A L K E + SKL+ ++ L +
Sbjct: 555 HQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKS 614
Query: 136 EIQVVLEKPNGFSQSPTALYSSPPEVDTC----INEDVESLRKTVQDLLAKLQEA----K 187
+++ + + +S +T + +E +R Q + LQ +
Sbjct: 615 KLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSER 674
Query: 188 RQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQK-------------EAEVGELQR 234
H + A L + +E E S A++ + D+ E + EAE+ +
Sbjct: 675 AAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKEL 734
Query: 235 RLLGMETEHQ--------ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLRE 286
+L + Q + L E + L+ LR +++ ++E +K L +++ +
Sbjct: 735 EVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEMKK---LRQQLEAAEK 791
Query: 287 KIHHLD--------------DMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAY 332
+I HL+ L+ ++ K+ + E L V ++ + +Q LKEK A
Sbjct: 792 QIKHLEIEKNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAE 851
Query: 333 LEAENLEMHDRMEHLIEK 350
E + + M+ + K
Sbjct: 852 ASEEAVSVQRSMQETVNK 869
Score = 32.0 bits (71), Expect = 0.98
Identities = 35/151 (23%), Positives = 63/151 (41%), Gaps = 23/151 (15%)
Query: 200 TLSRYQREAEQSNV---ALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVA 256
T SRY R+ + AL+ ++ +EQ AE +L+R + T H V E E
Sbjct: 339 TSSRYARKISGTTALQEALKEKQQHIEQLLAE-RDLERAEVAKATSH------VGEIEQE 391
Query: 257 LEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVI 316
L R + ++ V L K+ L M+++ R+ +++ QL+ K +
Sbjct: 392 LALARDGH-------------DQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKV 438
Query: 317 QSKDATIQELKEKIAYLEAENLEMHDRMEHL 347
+ ++E LE + H R++ L
Sbjct: 439 EDLQFRVEEESITKGDLETQTKLEHARIKEL 469
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 57.8 bits (138), Expect = 2e-08
Identities = 57/296 (19%), Positives = 130/296 (43%), Gaps = 16/296 (5%)
Query: 91 IHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSLHRQEIQVVLEKPNGFS 148
++++ ++ + + IQE +Q+ E I + + R + + RQE +++ EK
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQE-EMMWEKEEKMR 352
Query: 149 QSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREA 208
+ ++ ++ + E + + +++L K+ E ++ + + E R Q +
Sbjct: 353 RQEEMMWEKEEKMRR-LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 411
Query: 209 EQSNVALQREEDRVEQKEAEVGELQRRLLGMETE-HQALLAKVREGEV--------ALEE 259
++ + R+E+++ ++E ++ E ++++ E + H+ K+RE E EE
Sbjct: 412 QEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQ--EKIREEEKRQEQEEMWRQEE 469
Query: 260 LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSK 319
+ ++EK EK + EK+ ++ + Q+ K+R+ E++ + I+ +
Sbjct: 470 KIREQEEIWRQKEKMHEQEK-IRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
Query: 320 DATIQELKEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSIRISK 375
+ I+E +EKI E E ++M EK Q E IR K
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584
Score = 56.6 bits (135), Expect = 4e-08
Identities = 66/310 (21%), Positives = 138/310 (44%), Gaps = 36/310 (11%)
Query: 75 EEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD--RNLGDSL 132
E+I + K R ++M+ EK +++ + + + E +++L E + K + R L + +
Sbjct: 328 EKIREQEEKMRRQEEMMWEKE-EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM 386
Query: 133 HRQE-IQVVLEKPNGFSQSPTALYSSPPEV-----DTCINEDVESLRKTVQDLLAK---- 182
H QE I+ EK + E + I E E +R+ + + +
Sbjct: 387 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKI 446
Query: 183 ------LQEAKRQHQSDCVAFEVTLSRYQREA--------EQSNVALQ-----REEDRVE 223
+E KRQ Q + E + R Q E EQ + Q R+E+++
Sbjct: 447 HEQEKIREEEKRQEQEEMWRQEEKI-REQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505
Query: 224 QKEAEVGELQRRLLGMETEHQALLAKVREGEVAL---EELRSNNADCQAEREKAATLEKE 280
+E ++ E + ++ E + + K+RE E + EE+ + E+E+ +++
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEK 565
Query: 281 VAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEM 340
+ EKI ++ ++ Q+ K+R+ E++ + I+ ++ +QE +EK+ E + E
Sbjct: 566 MRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQ 625
Query: 341 HDRMEHLIEK 350
++M+ EK
Sbjct: 626 EEKMQEQEEK 635
Score = 55.5 bits (132), Expect = 8e-08
Identities = 68/336 (20%), Positives = 135/336 (40%), Gaps = 35/336 (10%)
Query: 44 QKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEV 103
+K T ++ HS E SH H+E ++ L+ + I +L+ +
Sbjct: 88 KKINNGTNPETTTSGGCHSPEDEQKASHQ-HQEALRRELEAQVHTIRILTCQKTELQMAL 146
Query: 104 QYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDT 163
Y Q A L+ D+ S+L + + Q+ +A+ + + D
Sbjct: 147 YYSQHAVKQLEGEARDLISRLHDSW-------------KFAGELEQALSAVATQKKKADR 193
Query: 164 CINE--------DVESLRKTVQD-----LLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQ 210
I E +E R T+ D AKLQE + +S+ ++ + +R+ E+
Sbjct: 194 YIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLER 253
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAE 270
+ + L ++ Q +AE L + L + + QA +V E E+ + +
Sbjct: 254 AKLLLPQQ-----QLQAEADHLGKELQSVSAKLQA---QVEENELWNRLNQQQEEKMWRQ 305
Query: 271 REKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI 330
EK E+++ EKI ++ ++ Q+ K+R+ E + + ++ ++ + E +EK+
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 331 AYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTE 366
LE E +++ L EK Q + E
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 401
Score = 50.4 bits (119), Expect = 3e-06
Identities = 39/183 (21%), Positives = 88/183 (48%), Gaps = 11/183 (6%)
Query: 170 ESLRKTVQDLLAKLQEAKRQHQSDCVAF-EVTLSRYQREAEQSNVALQREEDRVEQKEAE 228
E +RK Q+ QE K Q + + E + R + + + ++ +E+++ ++E E
Sbjct: 488 EKIRK--QEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE-E 544
Query: 229 VGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKI 288
+ + Q +G + E K+R E E++R + ++EK E+++ EKI
Sbjct: 545 MMQEQEEKMGEQEEKMQEQEKMRRQE---EKIREQEEKIREQKEKIREQEEKIWEQEEKI 601
Query: 289 HHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI----AYLEAENLEMHDRM 344
++M++ Q+ K+ + E++ + +Q ++ ++ +EK+ L + +M +
Sbjct: 602 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
Query: 345 EHL 347
EHL
Sbjct: 662 EHL 664
Score = 48.9 bits (115), Expect = 8e-06
Identities = 32/174 (18%), Positives = 79/174 (45%), Gaps = 3/174 (1%)
Query: 184 QEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 243
QE R+ + E + + + + + R+E+++ ++E ++ E + ++ E
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546
Query: 244 QALLAKVREGEVALEE---LRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQR 300
Q K+ E E ++E +R + + EK ++++ EKI ++ ++ Q+
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEE 606
Query: 301 KVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISH 354
+++ E++ + + ++ +QE +EK+ E + E R+ EK H
Sbjct: 607 MMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 660
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/135 (20%), Positives = 66/135 (48%), Gaps = 3/135 (2%)
Query: 184 QEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEH 243
QE K + Q + + + Q E Q ++R+E+++ ++E ++ E + ++ E +
Sbjct: 535 QEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594
Query: 244 QALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVR 303
K+RE E ++E + + EK E+++ EK+ ++ + Q+ ++R
Sbjct: 595 WEQEEKIREQEEMMQEQEEKMWE---QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLR 651
Query: 304 QMIEQLQNSKAVIQS 318
Q E++Q + +++
Sbjct: 652 QQEEKMQEHQEHLEA 666
Score = 42.7 bits (99), Expect = 6e-04
Identities = 54/267 (20%), Positives = 122/267 (45%), Gaps = 10/267 (3%)
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 147
D+ + EKN +L+ ++Q ++ ++ +Q +++ KL+R L +Q++Q +
Sbjct: 216 DEELKEKNA-KLQEKLQLVESEKSEIQLNVKELKRKLER-AKLLLPQQQLQAEADHLGKE 273
Query: 148 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 207
QS +A + E + N + + + K+QE + + Q E + + +
Sbjct: 274 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ----EEKIREQEEK 329
Query: 208 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 267
+ ++R+E+ + +KE ++ + + E + + L + E E + EL +
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ 389
Query: 268 QAERE-KAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL 326
+ RE + E+E +EK + + Q+ K+R+ E+++ + + ++ I E
Sbjct: 390 EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHE- 448
Query: 327 KEKIAYLE--AENLEMHDRMEHLIEKQ 351
+EKI E E EM + E + E++
Sbjct: 449 QEKIREEEKRQEQEEMWRQEEKIREQE 475
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 57.8 bits (138), Expect = 2e-08
Identities = 75/330 (22%), Positives = 141/330 (42%), Gaps = 29/330 (8%)
Query: 42 IAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKS 101
+AQ+ G T + + S+AS +S D + S + + I +L++
Sbjct: 15 VAQRPGGAT--RIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEA 72
Query: 102 EVQ-YIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPE 160
+ Y ++ RN LQK++E + L+++ S+ + + Q + N ++ L +
Sbjct: 73 RLSDYAEQVRN-LQKIKEKLEIALEKHQDSSMRKFQEQNETFQANR-AKMAEGLALALAR 130
Query: 161 VDTCINEDVESLRKTVQDLLAKLQEAKRQHQS---------DCVAFEVT-LSRYQREAEQ 210
D +E ++ L K L A+LQE K Q + + F+ LS+ + +
Sbjct: 131 KDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLK 190
Query: 211 SNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAE 270
+L + E +E + E+ Q L+ L K LEEL+ + + + +
Sbjct: 191 KEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQK-------LEELQRHYSTLEEQ 243
Query: 271 REKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKI 330
R+ + G KI L+ + Q ++Q+ LQ A Q K+ I L+EK+
Sbjct: 244 RDHVIASK---TGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKV 300
Query: 331 AYLE---AENLEMHDRMEHLI-EKQISHGN 356
A LE +NL + ++ L+ EK ++ N
Sbjct: 301 ASLEKRLEQNLSGEEHVQELLKEKTLAEQN 330
Score = 46.6 bits (109), Expect = 4e-05
Identities = 68/339 (20%), Positives = 151/339 (44%), Gaps = 39/339 (11%)
Query: 38 ELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEEIIKVYLKGRSGDKMIHEKNIN 97
ELE ++ R +++S+ L+ +L E + + + D +I K
Sbjct: 201 ELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEE------QRDHVIASKT-- 252
Query: 98 QLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVL-EKPNGFSQSPTALYS 156
+S++ +++ LQ L + +S L + ++ ++++ L EK + S
Sbjct: 253 GAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLS 312
Query: 157 SPPEVDTCINEDV---ESLRKTVQDLLA-KLQEAKRQH--QSDCVAFEVTLSRYQREAEQ 210
V + E ++L T Q LLA + +AK + ++ E TL + + +Q
Sbjct: 313 GEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQLQQ 372
Query: 211 SNVALQREEDRVEQKEA---EVGELQRRLLGMETEH----QALLAKVREGEVALEELRSN 263
S + +E ++++ A E +Q++ L +E + QAL A++ VALE R+
Sbjct: 373 SKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQI----VALERTRA- 427
Query: 264 NADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATI 323
AD + LE+E A L+E + + L++ Q +++++ E+ + V + +
Sbjct: 428 -ADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQAL 486
Query: 324 QELKEK-----------IAYLEAENLEMHDRMEHLIEKQ 351
+E++++ A ++ + + ++ E L++K+
Sbjct: 487 EEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKE 525
Score = 45.4 bits (106), Expect = 9e-05
Identities = 51/260 (19%), Positives = 111/260 (42%), Gaps = 33/260 (12%)
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQ----VVLEK 143
D++ EKNI L +++Q ++ L + R+++ + +QE+ ++L+K
Sbjct: 140 DQLEKEKNI--LTAQLQEMKNQSMNLFQRRDEMDEL------EGFQQQELSKIKHMLLKK 191
Query: 144 PNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQH------------- 190
+ L + E+ E++ + + DL KL+E +R +
Sbjct: 192 EESLGKMEQELEARTRELSRT-QEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIAS 250
Query: 191 ----QSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQAL 246
+S A E Q +Q ++ LQ+ ++KE + LQ ++ +E +
Sbjct: 251 KTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQN 310
Query: 247 LAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMI 306
L+ + L+E + + R++ A + I+ L+ ++ ++ ++
Sbjct: 311 LSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQA---KAINTLETRVRELEQTLQASE 367
Query: 307 EQLQNSKAVIQSKDATIQEL 326
EQLQ SK ++ +++ IQEL
Sbjct: 368 EQLQQSKGIVAAQETQIQEL 387
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 57.4 bits (137), Expect = 2e-08
Identities = 76/384 (19%), Positives = 165/384 (42%), Gaps = 42/384 (10%)
Query: 16 EDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHS--LASELVESHDG 73
E++ S++ LRL + + E ++ GR+ + G S L ++VE
Sbjct: 1043 EEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR 1102
Query: 74 HEEIIKVYLKGRSGDKMIHEKNINQLKSE-------VQYIQEARNCLQKLREDISSKLDR 126
EE+ + L GR +++ + + + + E ++ ++EA+ L + +ED+ S+
Sbjct: 1103 AEEL-RAQL-GRKEEEL--QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1158
Query: 127 NLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL----AK 182
R+++ LE G + ++ E+ + ++V L+KT+++ A
Sbjct: 1159 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1218
Query: 183 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 242
+QE +++H L + EQ+ E EAEV EL+ L ++T
Sbjct: 1219 VQELRQRHGQ-------ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1271
Query: 243 HQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKV 302
Q + R E+ L+E++ D + R +AA +++ + ++ ++ L + K
Sbjct: 1272 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAA---EKLQRAQAELENVSGALNEAESKT 1328
Query: 303 RQMIEQLQNSKAVIQSKDATIQE-------LKEKIAYLEAENLEMHDRMEHLI------- 348
++ ++L +++A + +QE L ++ +EAE + +++E
Sbjct: 1329 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1388
Query: 349 -EKQISHGNFSTQARAKTENPGSI 371
E Q + S R + E G++
Sbjct: 1389 RELQTAQAQLSEWRRRQEEEAGAL 1412
Score = 43.1 bits (100), Expect = 4e-04
Identities = 37/171 (21%), Positives = 80/171 (46%), Gaps = 20/171 (11%)
Query: 215 LQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKA 274
LQ+ ++ +Q EVGELQ R+ +E E L ++R E A +++
Sbjct: 886 LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE- 944
Query: 275 ATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL-------- 326
LE V+ L ++ ++ + Q + +++ + +Q +A +++++ Q+L
Sbjct: 945 --LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 1002
Query: 327 ------KEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSI 371
+E + LE +N ++ + L+E +++ FS+QA + E S+
Sbjct: 1003 AKMKKFEEDLLLLEDQNSKL-SKERKLLEDRLA--EFSSQAAEEEEKVKSL 1050
Score = 38.5 bits (88), Expect = 0.010
Identities = 69/318 (21%), Positives = 130/318 (40%), Gaps = 40/318 (12%)
Query: 38 ELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEE----IIKVYLKGRSGDKMIHE 93
E E + Q+ KT + L EL ++ E+ + + K R D+++ E
Sbjct: 1425 EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1484
Query: 94 KNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT- 152
+ L++ + +E + RE + L R L + QE + LE+ N ++
Sbjct: 1485 EKAAVLRAVEE--RERAEAEGREREARALSLTRALEEE---QEAREELERQNRALRAELE 1539
Query: 153 ALYSSPPEVDTCINEDVESLRKTVQ---DLLAKLQEAKRQHQSDCVAFEVTLSRYQREAE 209
AL SS +V ++E + R Q DL A++ E + + A E R + +
Sbjct: 1540 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL----EDELTAAEDAKLRLEVTVQ 1595
Query: 210 QSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQA 269
AL+ + +R Q E GE +RR L + +R+ EV +E R A
Sbjct: 1596 ----ALKTQHERDLQGRDEAGEERRRQLAKQ---------LRDAEVERDEERKQRTLAVA 1642
Query: 270 EREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEK 329
R+K L ++ L + S + + ++QL+ +A ++ ++E +
Sbjct: 1643 ARKK----------LEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1692
Query: 330 IAYLEAENLEMHDRMEHL 347
+ ++N E R++ L
Sbjct: 1693 REEIFSQNRESEKRLKGL 1710
Score = 32.0 bits (71), Expect = 0.98
Identities = 37/198 (18%), Positives = 88/198 (44%), Gaps = 8/198 (4%)
Query: 168 DVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEA 227
+VE R + +++ ++ +E++++ + E + R Q E S+ A ++ + ++
Sbjct: 1685 EVEETRTSREEIFSQNRESEKRLKG----LEAEVLRLQEELAASDRARRQAQQDRDEMAD 1740
Query: 228 EVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREK 287
EV + E + L ++ + E LEE +SN+ + ++ L +V L +
Sbjct: 1741 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS---ELLNDRYRKLLLQVESLTTE 1797
Query: 288 IHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQ-ELKEKIAYLEAENLEMHDRMEH 346
+ + +Q+ Q+Q + + +DA + K IA LE++ + +++E
Sbjct: 1798 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ 1857
Query: 347 LIEKQISHGNFSTQARAK 364
++I G +A +
Sbjct: 1858 ETRERILSGKLVRRAEKR 1875
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 57.4 bits (137), Expect = 2e-08
Identities = 76/384 (19%), Positives = 165/384 (42%), Gaps = 42/384 (10%)
Query: 16 EDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHS--LASELVESHDG 73
E++ S++ LRL + + E ++ GR+ + G S L ++VE
Sbjct: 1035 EEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR 1094
Query: 74 HEEIIKVYLKGRSGDKMIHEKNINQLKSE-------VQYIQEARNCLQKLREDISSKLDR 126
EE+ + L GR +++ + + + + E ++ ++EA+ L + +ED+ S+
Sbjct: 1095 AEEL-RAQL-GRKEEEL--QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1150
Query: 127 NLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL----AK 182
R+++ LE G + ++ E+ + ++V L+KT+++ A
Sbjct: 1151 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1210
Query: 183 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 242
+QE +++H L + EQ+ E EAEV EL+ L ++T
Sbjct: 1211 VQELRQRHGQ-------ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1263
Query: 243 HQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKV 302
Q + R E+ L+E++ D + R +AA +++ + ++ ++ L + K
Sbjct: 1264 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAA---EKLQRAQAELENVSGALNEAESKT 1320
Query: 303 RQMIEQLQNSKAVIQSKDATIQE-------LKEKIAYLEAENLEMHDRMEHLI------- 348
++ ++L +++A + +QE L ++ +EAE + +++E
Sbjct: 1321 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1380
Query: 349 -EKQISHGNFSTQARAKTENPGSI 371
E Q + S R + E G++
Sbjct: 1381 RELQTAQAQLSEWRRRQEEEAGAL 1404
Score = 43.1 bits (100), Expect = 4e-04
Identities = 37/171 (21%), Positives = 80/171 (46%), Gaps = 20/171 (11%)
Query: 215 LQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKA 274
LQ+ ++ +Q EVGELQ R+ +E E L ++R E A +++
Sbjct: 878 LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE- 936
Query: 275 ATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL-------- 326
LE V+ L ++ ++ + Q + +++ + +Q +A +++++ Q+L
Sbjct: 937 --LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 994
Query: 327 ------KEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSI 371
+E + LE +N ++ + L+E +++ FS+QA + E S+
Sbjct: 995 AKMKKFEEDLLLLEDQNSKL-SKERKLLEDRLA--EFSSQAAEEEEKVKSL 1042
Score = 38.5 bits (88), Expect = 0.010
Identities = 69/318 (21%), Positives = 130/318 (40%), Gaps = 40/318 (12%)
Query: 38 ELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEE----IIKVYLKGRSGDKMIHE 93
E E + Q+ KT + L EL ++ E+ + + K R D+++ E
Sbjct: 1417 EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1476
Query: 94 KNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT- 152
+ L++ + +E + RE + L R L + QE + LE+ N ++
Sbjct: 1477 EKAAVLRAVEE--RERAEAEGREREARALSLTRALEEE---QEAREELERQNRALRAELE 1531
Query: 153 ALYSSPPEVDTCINEDVESLRKTVQ---DLLAKLQEAKRQHQSDCVAFEVTLSRYQREAE 209
AL SS +V ++E + R Q DL A++ E + + A E R + +
Sbjct: 1532 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL----EDELTAAEDAKLRLEVTVQ 1587
Query: 210 QSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQA 269
AL+ + +R Q E GE +RR L + +R+ EV +E R A
Sbjct: 1588 ----ALKTQHERDLQGRDEAGEERRRQLAKQ---------LRDAEVERDEERKQRTLAVA 1634
Query: 270 EREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEK 329
R+K L ++ L + S + + ++QL+ +A ++ ++E +
Sbjct: 1635 ARKK----------LEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1684
Query: 330 IAYLEAENLEMHDRMEHL 347
+ ++N E R++ L
Sbjct: 1685 REEIFSQNRESEKRLKGL 1702
Score = 32.0 bits (71), Expect = 0.98
Identities = 37/198 (18%), Positives = 88/198 (44%), Gaps = 8/198 (4%)
Query: 168 DVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEA 227
+VE R + +++ ++ +E++++ + E + R Q E S+ A ++ + ++
Sbjct: 1677 EVEETRTSREEIFSQNRESEKRLKG----LEAEVLRLQEELAASDRARRQAQQDRDEMAD 1732
Query: 228 EVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREK 287
EV + E + L ++ + E LEE +SN+ + ++ L +V L +
Sbjct: 1733 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS---ELLNDRYRKLLLQVESLTTE 1789
Query: 288 IHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQ-ELKEKIAYLEAENLEMHDRMEH 346
+ + +Q+ Q+Q + + +DA + K IA LE++ + +++E
Sbjct: 1790 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ 1849
Query: 347 LIEKQISHGNFSTQARAK 364
++I G +A +
Sbjct: 1850 ETRERILSGKLVRRAEKR 1867
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 57.4 bits (137), Expect = 2e-08
Identities = 76/384 (19%), Positives = 165/384 (42%), Gaps = 42/384 (10%)
Query: 16 EDQAAGSVDILRLTLQGELTGDELEHIAQKAGRKTYAMVSSHSAGHS--LASELVESHDG 73
E++ S++ LRL + + E ++ GR+ + G S L ++VE
Sbjct: 1076 EEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR 1135
Query: 74 HEEIIKVYLKGRSGDKMIHEKNINQLKSE-------VQYIQEARNCLQKLREDISSKLDR 126
EE+ + L GR +++ + + + + E ++ ++EA+ L + +ED+ S+
Sbjct: 1136 AEEL-RAQL-GRKEEEL--QAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1191
Query: 127 NLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCINEDVESLRKTVQDLL----AK 182
R+++ LE G + ++ E+ + ++V L+KT+++ A
Sbjct: 1192 RTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAA 1251
Query: 183 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETE 242
+QE +++H L + EQ+ E EAEV EL+ L ++T
Sbjct: 1252 VQELRQRHGQ-------ALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1304
Query: 243 HQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKV 302
Q + R E+ L+E++ D + R +AA +++ + ++ ++ L + K
Sbjct: 1305 RQEGEQRRRRLELQLQEVQGRAGDGERARAEAA---EKLQRAQAELENVSGALNEAESKT 1361
Query: 303 RQMIEQLQNSKAVIQSKDATIQE-------LKEKIAYLEAENLEMHDRMEHLI------- 348
++ ++L +++A + +QE L ++ +EAE + +++E
Sbjct: 1362 IRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAG 1421
Query: 349 -EKQISHGNFSTQARAKTENPGSI 371
E Q + S R + E G++
Sbjct: 1422 RELQTAQAQLSEWRRRQEEEAGAL 1445
Score = 43.1 bits (100), Expect = 4e-04
Identities = 37/171 (21%), Positives = 80/171 (46%), Gaps = 20/171 (11%)
Query: 215 LQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKA 274
LQ+ ++ +Q EVGELQ R+ +E E L ++R E A +++
Sbjct: 919 LQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQE- 977
Query: 275 ATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL-------- 326
LE V+ L ++ ++ + Q + +++ + +Q +A +++++ Q+L
Sbjct: 978 --LELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 1035
Query: 327 ------KEKIAYLEAENLEMHDRMEHLIEKQISHGNFSTQARAKTENPGSI 371
+E + LE +N ++ + L+E +++ FS+QA + E S+
Sbjct: 1036 AKMKKFEEDLLLLEDQNSKL-SKERKLLEDRLA--EFSSQAAEEEEKVKSL 1083
Score = 38.5 bits (88), Expect = 0.010
Identities = 69/318 (21%), Positives = 130/318 (40%), Gaps = 40/318 (12%)
Query: 38 ELEHIAQKAGRKTYAMVSSHSAGHSLASELVESHDGHEE----IIKVYLKGRSGDKMIHE 93
E E + Q+ KT + L EL ++ E+ + + K R D+++ E
Sbjct: 1458 EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAE 1517
Query: 94 KNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGFSQSPT- 152
+ L++ + +E + RE + L R L + QE + LE+ N ++
Sbjct: 1518 EKAAVLRAVEE--RERAEAEGREREARALSLTRALEEE---QEAREELERQNRALRAELE 1572
Query: 153 ALYSSPPEVDTCINEDVESLRKTVQ---DLLAKLQEAKRQHQSDCVAFEVTLSRYQREAE 209
AL SS +V ++E + R Q DL A++ E + + A E R + +
Sbjct: 1573 ALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTEL----EDELTAAEDAKLRLEVTVQ 1628
Query: 210 QSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQA 269
AL+ + +R Q E GE +RR L + +R+ EV +E R A
Sbjct: 1629 ----ALKTQHERDLQGRDEAGEERRRQLAKQ---------LRDAEVERDEERKQRTLAVA 1675
Query: 270 EREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEK 329
R+K L ++ L + S + + ++QL+ +A ++ ++E +
Sbjct: 1676 ARKK----------LEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTS 1725
Query: 330 IAYLEAENLEMHDRMEHL 347
+ ++N E R++ L
Sbjct: 1726 REEIFSQNRESEKRLKGL 1743
Score = 32.0 bits (71), Expect = 0.98
Identities = 37/198 (18%), Positives = 88/198 (44%), Gaps = 8/198 (4%)
Query: 168 DVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEA 227
+VE R + +++ ++ +E++++ + E + R Q E S+ A ++ + ++
Sbjct: 1718 EVEETRTSREEIFSQNRESEKRLKG----LEAEVLRLQEELAASDRARRQAQQDRDEMAD 1773
Query: 228 EVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREK 287
EV + E + L ++ + E LEE +SN+ + ++ L +V L +
Sbjct: 1774 EVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNS---ELLNDRYRKLLLQVESLTTE 1830
Query: 288 IHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQ-ELKEKIAYLEAENLEMHDRMEH 346
+ + +Q+ Q+Q + + +DA + K IA LE++ + +++E
Sbjct: 1831 LSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQ 1890
Query: 347 LIEKQISHGNFSTQARAK 364
++I G +A +
Sbjct: 1891 ETRERILSGKLVRRAEKR 1908
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 57.4 bits (137), Expect = 2e-08
Identities = 58/274 (21%), Positives = 119/274 (43%), Gaps = 35/274 (12%)
Query: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLDRNLGDSLHRQEIQVVLEKPNGF 147
+K E + L E+ ++E + L K ++ + + L D +QV +K NG
Sbjct: 971 EKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD------LQVEEDKVNGL 1024
Query: 148 SQSPTALYSSPPEVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQRE 207
+ L +D+E + + L A L+ AKR+ + D + ++ + +
Sbjct: 1025 IKINAKLEQQ--------TDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLEND 1076
Query: 208 AEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELRSNNADC 267
+Q E+++++KE E+ +LQ ++ + K++E + +EEL +
Sbjct: 1077 KQQI-------EEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEE---EI 1126
Query: 268 QAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQS-----KDAT 322
+AE A +EK+ + L ++ + + L+ IE + +A Q ++AT
Sbjct: 1127 EAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEAT 1186
Query: 323 IQE------LKEKIAYLEAENLEMHDRMEHLIEK 350
+Q L++K A AE E D ++ + +K
Sbjct: 1187 LQHEATAATLRKKQADSVAELGEQIDNLQRVKQK 1220
Score = 54.3 bits (129), Expect = 2e-07
Identities = 60/290 (20%), Positives = 120/290 (41%), Gaps = 23/290 (7%)
Query: 66 ELVESHDGHEEIIKVYLKGRSGDKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD 125
EL + E +I K + E+ Q++ E + + LQ R D +
Sbjct: 1290 ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLRE 1349
Query: 126 RNLGDSLHRQEIQVVLEKPNGFSQSPTALYSSPPEVDTCIN-EDVESLRKTVQDLLAKLQ 184
+ + + E+Q L K N S A + + E D E++E +K + L + +
Sbjct: 1350 QYEEEQEAKAELQRALSKAN----SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAE 1405
Query: 185 EAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEVGELQRRLLGMETEHQ 244
E S C + E T R Q E E L R+ +R A + + QR
Sbjct: 1406 ENTETANSKCASLEKTKQRLQGEVED----LMRDLERSHTACATLDKKQRNF-------D 1454
Query: 245 ALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRKVRQ 304
+LA+ + ++L + A+ +A ++++ +L E+ +R + D L++ +R+ +
Sbjct: 1455 KVLAEWK------QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKN 1508
Query: 305 MIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRMEHLIEKQISH 354
+ E++ + I +QE ++ +E E ++ +E +E + H
Sbjct: 1509 LQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEE-VEGSLEH 1557
Score = 35.8 bits (81), Expect = 0.068
Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 14/174 (8%)
Query: 180 LAKLQEAKRQHQSDCVAFEVTLSRYQR------EAEQSNVALQREED----RVEQKEAEV 229
L K EA+++ + FE T R E E+ V+L +E++ +V+ + +
Sbjct: 843 LLKSAEAEKEMATMKEDFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENL 902
Query: 230 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 289
+ + R G+ L AKV+E LEE N++ A K LE + + L+ I
Sbjct: 903 MDAEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVA---KKRNLEDKCSSLKRDID 959
Query: 290 HLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQEL-KEKIAYLEAENLEMHD 342
L+ L +++ +++N + + + I +L KEK + EA + D
Sbjct: 960 DLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDD 1013
Score = 32.3 bits (72), Expect = 0.75
Identities = 43/172 (25%), Positives = 77/172 (44%), Gaps = 30/172 (17%)
Query: 203 RYQREAEQSN--VALQRE-EDRVEQKEAEVGELQRRLLGMETEHQALLAKVR---EGEVA 256
R + E E ++ VA +R ED+ + ++ +L+ L +E E A KV+ E A
Sbjct: 929 RLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTA 988
Query: 257 LEELRSNNA---------------DCQAEREKAATLEKEVAGLREKIHHLDDMLKSQQRK 301
LEE S D Q E +K L K A L ++ L+ L+ Q++K
Sbjct: 989 LEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLE-QEKK 1047
Query: 302 VRQMIEQ--------LQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRME 345
+R +E+ L+ S+ I + Q+++EK+ E E ++ +++
Sbjct: 1048 LRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKID 1099
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,896,940
Number of Sequences: 37866
Number of extensions: 601866
Number of successful extensions: 7425
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 331
Number of HSP's successfully gapped in prelim test: 718
Number of HSP's that attempted gapping in prelim test: 3428
Number of HSP's gapped (non-prelim): 3005
length of query: 390
length of database: 18,247,518
effective HSP length: 104
effective length of query: 286
effective length of database: 14,309,454
effective search space: 4092503844
effective search space used: 4092503844
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.