Guide to the Human Genome
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Search of human proteins with 98991763

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|98991763 eyes absent 4 isoform b [Homo sapiens]
         (616 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|98991763 eyes absent 4 isoform b [Homo sapiens]                   1239   0.0  
gi|98991760 eyes absent 4 isoform a [Homo sapiens]                   1224   0.0  
gi|26667257 eyes absent 4 isoform d [Homo sapiens]                   1206   0.0  
gi|19923100 eyes absent 1 isoform b [Homo sapiens]                    847   0.0  
gi|26667216 eyes absent 1 isoform b [Homo sapiens]                    847   0.0  
gi|26667222 eyes absent 1 isoform a [Homo sapiens]                    817   0.0  
gi|26667219 eyes absent 1 isoform c [Homo sapiens]                    772   0.0  
gi|26667227 eyes absent 2 isoform a [Homo sapiens]                    607   e-173
gi|26667240 eyes absent 2 isoform b [Homo sapiens]                    607   e-173
gi|26667235 eyes absent 2 isoform a [Homo sapiens]                    607   e-173
gi|26667232 eyes absent 2 isoform a [Homo sapiens]                    607   e-173
gi|26667230 eyes absent 2 isoform c [Homo sapiens]                    576   e-164
gi|26667243 eyes absent 3 [Homo sapiens]                              575   e-164
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        55   2e-07
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    53   9e-07
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             52   1e-06
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    49   1e-05
gi|151301154 mucin 6, gastric [Homo sapiens]                           49   1e-05
gi|24430146 nucleoporin 153kDa [Homo sapiens]                          48   3e-05
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             46   1e-04
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s...    45   2e-04
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s...    45   3e-04
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap...    44   3e-04
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        44   3e-04
gi|89026265 PREDICTED: mucin 12 [Homo sapiens]                         44   3e-04
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    44   3e-04
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s...    44   4e-04
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     44   6e-04
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     44   6e-04
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             43   7e-04

>gi|98991763 eyes absent 4 isoform b [Homo sapiens]
          Length = 616

 Score = 1239 bits (3205), Expect = 0.0
 Identities = 616/616 (100%), Positives = 616/616 (100%)

Query: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60
           MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS
Sbjct: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60

Query: 61  TSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLY 120
           TSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLY
Sbjct: 61  TSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLY 120

Query: 121 PSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIK 180
           PSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIK
Sbjct: 121 PSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIK 180

Query: 181 TESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNF 240
           TESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNF
Sbjct: 181 TESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNF 240

Query: 241 SGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQP 300
           SGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQP
Sbjct: 241 SGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQP 300

Query: 301 GEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNPSPPPDSDLERVFVWDLDETIIVF 360
           GEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNPSPPPDSDLERVFVWDLDETIIVF
Sbjct: 301 GEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNPSPPPDSDLERVFVWDLDETIIVF 360

Query: 361 HSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 420
           HSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG
Sbjct: 361 HSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 420

Query: 421 QDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLL 480
           QDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLL
Sbjct: 421 QDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLL 480

Query: 481 GPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYS 540
           GPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYS
Sbjct: 481 GPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYS 540

Query: 541 LGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISS 600
           LGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISS
Sbjct: 541 LGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISS 600

Query: 601 HSDLLALHQALELEYL 616
           HSDLLALHQALELEYL
Sbjct: 601 HSDLLALHQALELEYL 616


>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
          Length = 639

 Score = 1224 bits (3168), Expect = 0.0
 Identities = 615/639 (96%), Positives = 616/639 (96%), Gaps = 23/639 (3%)

Query: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60
           MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS
Sbjct: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60

Query: 61  TSVTTNGTG-----------------------VSLLAVKTEPLNSSETTATTGDGALDTF 97
           TSVTTNGTG                       +SLLAVKTEPLNSSETTATTGDGALDTF
Sbjct: 61  TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF 120

Query: 98  TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 157
           TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA
Sbjct: 121 TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 180

Query: 158 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 217
           YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM
Sbjct: 181 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 240

Query: 218 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 277
           PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA
Sbjct: 241 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 300

Query: 278 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 337
           DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP
Sbjct: 301 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 360

Query: 338 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 397
           SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH
Sbjct: 361 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 420

Query: 398 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 457
           LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK
Sbjct: 421 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 480

Query: 458 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 517
           LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS
Sbjct: 481 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 540

Query: 518 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV 577
           NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV
Sbjct: 541 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV 600

Query: 578 IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL
Sbjct: 601 IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639


>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
          Length = 639

 Score = 1206 bits (3119), Expect = 0.0
 Identities = 604/639 (94%), Positives = 609/639 (95%), Gaps = 23/639 (3%)

Query: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60
           MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS
Sbjct: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60

Query: 61  TSVTTNGTG-----------------------VSLLAVKTEPLNSSETTATTGDGALDTF 97
           TSVTTNGTG                       +SLLAVKTEPLNSSETTATTGDGALDTF
Sbjct: 61  TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF 120

Query: 98  TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 157
           TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA
Sbjct: 121 TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 180

Query: 158 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 217
           YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM
Sbjct: 181 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 240

Query: 218 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 277
           PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA
Sbjct: 241 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 300

Query: 278 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 337
           DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP
Sbjct: 301 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 360

Query: 338 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 397
           SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH
Sbjct: 361 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 420

Query: 398 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 457
           LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK
Sbjct: 421 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 480

Query: 458 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 517
           LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS
Sbjct: 481 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 540

Query: 518 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV 577
           NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERI+ RFG  + YVV
Sbjct: 541 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVV 600

Query: 578 IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           IGDG +EE AA +HNMPFWRISSHSDLLALHQALELEYL
Sbjct: 601 IGDGRDEEHAANQHNMPFWRISSHSDLLALHQALELEYL 639


>gi|19923100 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score =  847 bits (2189), Expect = 0.0
 Identities = 436/600 (72%), Positives = 497/600 (82%), Gaps = 21/600 (3%)

Query: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTAT 88
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT      VKTEP++SSET +T
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-----EVKTEPMSSSETAST 55

Query: 89  TGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILSTPAAQTMSAYAGQTQY 146
           T DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL TP++QTM+AY GQTQ+
Sbjct: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAY-GQTQF 114

Query: 147 S-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFST 205
           + GMQQ   Y  Y Q GQPY + +Y  G +   IKTE GLSQ+QSP Q+G LSY   FST
Sbjct: 115 TTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTEGGLSQSQSPGQTGFLSYGTSFST 172

Query: 206 PQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 264
           PQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYPSY +FGQ QYAQYY++
Sbjct: 173 PQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNS 232

Query: 265 STYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GEFDTMQSPSTPIKDLD- 317
           S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E+ T+ SPSTPIKD D 
Sbjct: 233 SPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDS 292

Query: 318 ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDP 376
           +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVFHSLLTGSYA +YG+DP
Sbjct: 293 DRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDP 352

Query: 377 PMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAA 436
           P +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTY+F TDGF AA
Sbjct: 353 PTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAA 412

Query: 437 ASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIE 496
           A+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLLGPAKR+AWLQLRAEIE
Sbjct: 413 ATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIE 472

Query: 497 GLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKI 556
            LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY LG  FPIENIYSATKI
Sbjct: 473 ALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKI 532

Query: 557 GKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           GKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH MPFWRISSHSDL+ALH ALELEYL
Sbjct: 533 GKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592


>gi|26667216 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score =  847 bits (2189), Expect = 0.0
 Identities = 436/600 (72%), Positives = 497/600 (82%), Gaps = 21/600 (3%)

Query: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTAT 88
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT      VKTEP++SSET +T
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-----EVKTEPMSSSETAST 55

Query: 89  TGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILSTPAAQTMSAYAGQTQY 146
           T DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL TP++QTM+AY GQTQ+
Sbjct: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAY-GQTQF 114

Query: 147 S-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFST 205
           + GMQQ   Y  Y Q GQPY + +Y  G +   IKTE GLSQ+QSP Q+G LSY   FST
Sbjct: 115 TTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTEGGLSQSQSPGQTGFLSYGTSFST 172

Query: 206 PQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 264
           PQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYPSY +FGQ QYAQYY++
Sbjct: 173 PQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNS 232

Query: 265 STYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GEFDTMQSPSTPIKDLD- 317
           S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E+ T+ SPSTPIKD D 
Sbjct: 233 SPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDS 292

Query: 318 ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDP 376
           +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVFHSLLTGSYA +YG+DP
Sbjct: 293 DRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGRDP 352

Query: 377 PMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAA 436
           P +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTY+F TDGF AA
Sbjct: 353 PTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAA 412

Query: 437 ASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIE 496
           A+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLLGPAKR+AWLQLRAEIE
Sbjct: 413 ATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIE 472

Query: 497 GLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKI 556
            LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY LG  FPIENIYSATKI
Sbjct: 473 ALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKI 532

Query: 557 GKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           GKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH MPFWRISSHSDL+ALH ALELEYL
Sbjct: 533 GKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 592


>gi|26667222 eyes absent 1 isoform a [Homo sapiens]
          Length = 559

 Score =  817 bits (2111), Expect = 0.0
 Identities = 416/556 (74%), Positives = 471/556 (84%), Gaps = 15/556 (2%)

Query: 73  LAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILS 130
           +AVKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL 
Sbjct: 7   VAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILP 66

Query: 131 TPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQ 189
           TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE GLSQ+Q
Sbjct: 67  TPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTEGGLSQSQ 123

Query: 190 SPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYP 248
           SP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYP
Sbjct: 124 SPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYP 183

Query: 249 SYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GE 302
           SY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E
Sbjct: 184 SYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAE 243

Query: 303 FDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVF 360
           + T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVF
Sbjct: 244 YSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVF 303

Query: 361 HSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 420
           HSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG
Sbjct: 304 HSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 363

Query: 421 QDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLL 480
           QDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLL
Sbjct: 364 QDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLL 423

Query: 481 GPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYS 540
           GPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY 
Sbjct: 424 GPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYG 483

Query: 541 LGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISS 600
           LG  FPIENIYSATKIGKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH MPFWRISS
Sbjct: 484 LGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISS 543

Query: 601 HSDLLALHQALELEYL 616
           HSDL+ALH ALELEYL
Sbjct: 544 HSDLMALHHALELEYL 559


>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
          Length = 557

 Score =  772 bits (1994), Expect = 0.0
 Identities = 408/600 (68%), Positives = 466/600 (77%), Gaps = 56/600 (9%)

Query: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTAT 88
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT      VKTEP++SSET +T
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-----EVKTEPMSSSETAST 55

Query: 89  TGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILSTPAAQTMSAYAGQTQY 146
           T DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL TP++QTM+AY GQTQ+
Sbjct: 56  TADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILPTPSSQTMAAY-GQTQF 114

Query: 147 S-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFST 205
           + GMQQ   Y  Y Q GQPY + +Y        IKTE GLSQ+QSP Q+G LSY   FST
Sbjct: 115 TTGMQQATAYATYPQPGQPYGISSY-------GIKTEGGLSQSQSPGQTGFLSYGTSFST 167

Query: 206 PQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 264
           PQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYPSY +FGQ QYAQYY++
Sbjct: 168 PQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYPSYPSFGQGQYAQYYNS 227

Query: 265 STYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GEFDTMQSPSTPIKDLD- 317
           S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E+ T+ SPSTPIKD D 
Sbjct: 228 SPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAEYSTIHSPSTPIKDSDS 287

Query: 318 ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDP 376
           +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVFHSLLTGSYA +YG+  
Sbjct: 288 DRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVFHSLLTGSYANRYGR-- 345

Query: 377 PMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAA 436
                                       ECDQVHIDDVSSDDNGQDLSTY+F TDGF AA
Sbjct: 346 ----------------------------ECDQVHIDDVSSDDNGQDLSTYNFGTDGFPAA 377

Query: 437 ASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIE 496
           A+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLLGPAKR+AWLQLRAEIE
Sbjct: 378 ATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLLGPAKREAWLQLRAEIE 437

Query: 497 GLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKI 556
            LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY LG  FPIENIYSATKI
Sbjct: 438 ALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYGLGIVFPIENIYSATKI 497

Query: 557 GKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           GKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH MPFWRISSHSDL+ALH ALELEYL
Sbjct: 498 GKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISSHSDLMALHHALELEYL 557


>gi|26667227 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 110 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 168
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97

Query: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144

Query: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203

Query: 289 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 341
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263

Query: 342 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 401
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323

Query: 402 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 461
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383

Query: 462 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 521
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443

Query: 522 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 581
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503

Query: 582 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667240 eyes absent 2 isoform b [Homo sapiens]
          Length = 543

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 110 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 168
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 45  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 102

Query: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 103 SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 149

Query: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 150 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 208

Query: 289 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 341
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 209 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 268

Query: 342 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 401
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 269 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 328

Query: 402 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 461
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 329 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 388

Query: 462 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 521
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 389 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 448

Query: 522 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 581
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 449 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 508

Query: 582 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 509 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 543


>gi|26667235 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 110 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 168
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97

Query: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144

Query: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203

Query: 289 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 341
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263

Query: 342 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 401
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323

Query: 402 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 461
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383

Query: 462 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 521
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443

Query: 522 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 581
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503

Query: 582 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667232 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 110 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 168
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97

Query: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144

Query: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203

Query: 289 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 341
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263

Query: 342 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 401
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323

Query: 402 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 461
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383

Query: 462 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 521
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443

Query: 522 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 581
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503

Query: 582 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667230 eyes absent 2 isoform c [Homo sapiens]
          Length = 514

 Score =  576 bits (1485), Expect = e-164
 Identities = 304/515 (59%), Positives = 365/515 (70%), Gaps = 48/515 (9%)

Query: 110 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 168
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97

Query: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
           +                                 FST   GQ+PY+YQM G++       
Sbjct: 98  S---------------------------------FSTSPTGQSPYTYQMHGTT----GFY 120

Query: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 121 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 179

Query: 289 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 341
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 180 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 239

Query: 342 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 401
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 240 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 299

Query: 402 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 461
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 300 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 359

Query: 462 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 521
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 360 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 419

Query: 522 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 581
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 420 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 479

Query: 582 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 480 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514


>gi|26667243 eyes absent 3 [Homo sapiens]
          Length = 573

 Score =  575 bits (1483), Expect = e-164
 Identities = 319/627 (50%), Positives = 411/627 (65%), Gaps = 65/627 (10%)

Query: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60
           ME+ QDL EQ VKK       ++ Q S    +  +++P             K E S+L+S
Sbjct: 1   MEEEQDLPEQPVKK-------AKMQESGEQTISQVSNPDV--------SDQKPETSSLAS 45

Query: 61  TSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLY 120
                              L  SE                ++T + Y PRS++ Y+ Q+Y
Sbjct: 46  N------------------LPMSE---------------EIMTCTDYIPRSSNDYTSQMY 72

Query: 121 PSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIK 180
            +KPY HILS P ++T  AY GQTQY  +QQ   Y  Y Q  Q Y LP +  G + P +K
Sbjct: 73  SAKPYAHILSVPVSET--AYPGQTQYQTLQQTQPYAVYPQATQTYGLPPF--GALWPGMK 128

Query: 181 TESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSN---S 237
            ESGL QT SP Q   L+ + G +T QP    YSY +  SS   +S I  +++++N   +
Sbjct: 129 PESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQASS-TNASLISTSSTIANIPAA 187

Query: 238 TNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQES---LP 294
              S S QDYP+YT  GQNQY   Y +S++G    +N+ A+ T  + +TYQ ++     P
Sbjct: 188 AVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDAESTTLAATTYQSEKPSVMAP 247

Query: 295 GLTNQP-GEFDTMQSPS----TPIKDLDERTCRSSGSKSRGRGRKNNPSPPPDSDLERVF 349
               Q     D   SPS    TP KD D+++ ++  SK+RG+ RK + +   DS+LERVF
Sbjct: 248 APAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTSKNRGK-RKADATSSQDSELERVF 306

Query: 350 VWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQV 409
           +WDLDETII+FHSLLTGSYAQKYGKDP + +  GL MEEMIF +ADTHLFFNDLEECDQV
Sbjct: 307 LWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEMIFEVADTHLFFNDLEECDQV 366

Query: 410 HIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELY 469
           H++DV+SDDNGQDLS YSF+TDGF  +  S +     GV+GGVDWMRKLAFRYR+V+E+Y
Sbjct: 367 HVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQGGVDWMRKLAFRYRKVREIY 426

Query: 470 NTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQL 529
           + +K+NVGGLL P +++A  +LRAEIE LTDSWL  ALKSL +I +R NC+NVL+TTTQL
Sbjct: 427 DKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKSLLLIQSRKNCVNVLITTTQL 486

Query: 530 IPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAK 589
           +PALAKVLLY LG  FPIENIYSATKIGKESCFERI+ RFG+KV YVVIGDG +EE AAK
Sbjct: 487 VPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRFGKKVTYVVIGDGRDEEIAAK 546

Query: 590 KHNMPFWRISSHSDLLALHQALELEYL 616
           +HNMPFWRI++H DL++LHQALEL++L
Sbjct: 547 QHNMPFWRITNHGDLVSLHQALELDFL 573


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 77/315 (24%), Positives = 121/315 (38%), Gaps = 45/315 (14%)

Query: 40   TLVGGGDTPGSSKLEKS----------NLSSTSVTTNGTGVSLLAVKTEPLNSSETTA-- 87
            TL G   TPG S+   +           LS  S+T+ G G      +++P ++  T +  
Sbjct: 2313 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2372

Query: 88   -TTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHIL-STPAAQTMSAYAGQTQ 145
             TT  G  +  T    +S G +  +    +P        P    S PA+   + +   + 
Sbjct: 2373 STTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDST 2432

Query: 146  YSGMQQPAVY----TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSP 201
             SG+ + +       A +QTG P +L T DLG       + SG + T         S   
Sbjct: 2433 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLV 2492

Query: 202  GFSTP---QPGQTPYSYQMPGSSFAP-----SSTIY-------ANNSVSNSTNFSGSQQD 246
            G STP    P  T  +  +PGS   P     S+T Y       A  S + +T+   S++ 
Sbjct: 2493 GESTPSRLSPSSTE-TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 2551

Query: 247  YPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQL----------QESLPGL 296
              S++  G      +  ++T       + T+  +P ST T  L          QES    
Sbjct: 2552 STSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTS- 2610

Query: 297  TNQPGEFDTMQSPST 311
             + PG  DT  SP +
Sbjct: 2611 HSSPGSTDTALSPGS 2625



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 76/317 (23%), Positives = 125/317 (39%), Gaps = 45/317 (14%)

Query: 40   TLVGGGDTPGSSKLEKS----------NLSSTSVTTNGTGVSLLAVKTEP--LNSSETTA 87
            TL G   TPG S+   +           LS  S+T+ G G      +++P   +S+ + A
Sbjct: 1230 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 1289

Query: 88   TTGDGALDTFTGSVITSSGYSPRSA---HQYSPQLYPSKPYPHILSTPAAQTMSAYAGQT 144
            +T    L   + +V +SS  S  +    H  +  ++  +P     S PA+   + +   +
Sbjct: 1290 STTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTT-FHSRPASTHTTLFTEDS 1348

Query: 145  QYSGMQQPAVY----TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYS 200
              SG+ + +       A +QTG P +L T DLG       + SG + T+        S  
Sbjct: 1349 TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 1408

Query: 201  PGFSTP---QPGQTPYSYQMPGSSFAP-----SSTIY---------------ANNSVSNS 237
             G STP    P  T  +  +PGS   P     S+T Y                ++ VS  
Sbjct: 1409 VGESTPSRLSPSSTE-TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 1467

Query: 238  TNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-ADGTPSSTSTYQLQESLPGL 296
            ++ S SQ      TAF  +      S     ++ +  +T A  +P ST+   L +     
Sbjct: 1468 SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF 1527

Query: 297  TNQPGEFDTMQSPSTPI 313
             + PG+ +T   P   I
Sbjct: 1528 HSSPGDTETTLLPDDTI 1544



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 75/316 (23%), Positives = 120/316 (37%), Gaps = 43/316 (13%)

Query: 40   TLVGGGDTPGSSKLEKS----------NLSSTSVTTNGTGVSLLAVKTEPLNSSETTA-- 87
            TL G   TPG S+   +           LS  S+T+ G G      +++P ++  T +  
Sbjct: 3870 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 3929

Query: 88   -TTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHIL-STPAAQTMSAYAGQTQ 145
             TT  G  +  T    +S G +  +    S      +  P    S PA+   + +   + 
Sbjct: 3930 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDST 3989

Query: 146  YSGMQQPAVY----TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSP 201
             SG+ + +       A +QTG P +L T DLG       + SG + T+        S   
Sbjct: 3990 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLV 4049

Query: 202  GFSTP---QPGQTPYSYQMPGSSFAP-----SSTIY---------------ANNSVSNST 238
            G STP    P  T  +  +PGS   P     S+T Y                ++ VS  +
Sbjct: 4050 GESTPSRLSPSSTE-TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 4108

Query: 239  NFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-ADGTPSSTSTYQLQESLPGLT 297
            + S SQ      TAF  +      S     ++ +  +T A  +P ST+   L +      
Sbjct: 4109 STSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFH 4168

Query: 298  NQPGEFDTMQSPSTPI 313
            + PG+ +T   P   I
Sbjct: 4169 SSPGDTETTLLPDDTI 4184



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 77/320 (24%), Positives = 125/320 (39%), Gaps = 51/320 (15%)

Query: 40   TLVGGGDTPGSSKLEKS----------NLSSTSVTTNGTGVSLLAVKTEPLNSSETTA-- 87
            TL G   TPG S+   +           LS  S+T+ G G      +++P ++  T +  
Sbjct: 2787 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846

Query: 88   -TTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHIL-STPAAQTMSAYAGQTQ 145
             TT  G  +  T    +S G +  +    S         P    S PA+   + +   + 
Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDST 2906

Query: 146  YSGMQQPAVY----TAYSQTGQPYSLPTYDLG---------------VMLPAIKTESGLS 186
             SG+ + +       A +QTG P +L T DLG                + PA  T SGL 
Sbjct: 2907 TSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLV 2966

Query: 187  QTQSPLQSGCLSYSPGFSTPQPGQ--TP----------YSYQMPGSSFAPSSTIYANNSV 234
               +P +   LS S   +T  PG   TP           S + P ++ +P++T   ++ V
Sbjct: 2967 GESTPSR---LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT--TSSGV 3021

Query: 235  SNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-ADGTPSSTSTYQLQESL 293
            S  ++ S SQ      TAF  +      S     ++ +  +T A  +P ST+   L +  
Sbjct: 3022 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQS 3081

Query: 294  PGLTNQPGEFDTMQSPSTPI 313
                + PG+ +T   P   I
Sbjct: 3082 TTFHSSPGDTETTLLPDDTI 3101



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 89/340 (26%), Positives = 129/340 (37%), Gaps = 47/340 (13%)

Query: 9    EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
            E +   + T   +S + ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 856  ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 915

Query: 62   SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQL 119
            S    GT V      T  L    TT+    G+++T    GS  T+ G S RS   +S   
Sbjct: 916  SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGLSERSTTFHS--- 971

Query: 120  YPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY--SQTGQP---------YSLP 168
              S   P    +PA+ T S  + ++  S  +  + +T      T  P         +S P
Sbjct: 972  --SPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 1029

Query: 169  TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
                  +LPA  T SG SQ  +   S   S     S   PG T         SF   ST 
Sbjct: 1030 GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALS---PGST------TALSFGQESTT 1080

Query: 229  YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
            + +N  S  T        +P  T       A     S+ G+  T+ + A    SSTS   
Sbjct: 1081 FHSNPGSTHTTL------FPDSTTSSGIVEASTRVHSSTGSPRTTLSPA----SSTSPGL 1130

Query: 289  LQESLPGLTNQPGEFDTMQSPSTPIKDLDERTC--RSSGS 326
              ES    T+      T   PST    ++E T   RS GS
Sbjct: 1131 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 1170



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 87/340 (25%), Positives = 129/340 (37%), Gaps = 47/340 (13%)

Query: 9    EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
            E +   + T   +S + ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 3496 ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 3555

Query: 62   SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQL 119
            S    GT V      T  L    TT+    G+++T    GS  T+ G S +S   +S   
Sbjct: 3556 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGLSEKSTTFHS--- 3611

Query: 120  YPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY--SQTGQP---------YSLP 168
              S   P    +PA+ T S  + ++  S  +  + +T      T  P         +S P
Sbjct: 3612 --SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 3669

Query: 169  TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
                  +LPA  T SG SQ  +   S   S     S   PG T         SF   ST 
Sbjct: 3670 GSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALS---PGST------TALSFGQESTT 3720

Query: 229  YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
            + ++  S  T        +P  T       A     S+ G+  T+ + A    SSTS   
Sbjct: 3721 FHSSPGSTHTTL------FPDSTTSSGIVEASTRVHSSTGSPRTTLSPA----SSTSPGL 3770

Query: 289  LQESLPGLTNQPGEFDTMQSPSTPIKDLDERTC--RSSGS 326
              ES    T+      T   PST    ++E T   RS GS
Sbjct: 3771 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 3810



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 72/285 (25%), Positives = 110/285 (38%), Gaps = 38/285 (13%)

Query: 48  PGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALD-TFTGSVITSSG 106
           P +S +  +++ +T++  + T        T  L+   TT  +   + D T + +  TSSG
Sbjct: 252 PKTSPITSASMETTALPGSTT--------TAGLSEKSTTFYSSPRSPDRTLSPARTTSSG 303

Query: 107 YSPRSAHQYSPQLYPSKPYP-HILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQ-TGQP 164
            S +S   +S      +P P H ++ P + TM   + ++  S     +  T  S  T  P
Sbjct: 304 VSEKSTTSHS------RPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTP 357

Query: 165 YSL----------PTYDLGVMLPAIKTESGLSQTQSPLQSGC----LSYSPGFSTPQPGQ 210
            SL          P Y     LP   T SGL +  +P+ S       + SP  ST   G+
Sbjct: 358 SSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGE 417

Query: 211 TPYSYQMPGS---SFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTY 267
                  P S   S APS T  A   V  ST +  S    P+ T F  +     +S  + 
Sbjct: 418 PTTFQSWPSSKDTSPAPSGTTSA--FVKLSTTYHSSPSSTPT-THFSASSTTLGHSEEST 474

Query: 268 GAYMTSNNTADGTPSSTS-TYQLQESLPGLTNQPGEFDTMQSPST 311
             + +   TA   P + S T    E        PG   TM  P +
Sbjct: 475 PVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPES 519



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 88/342 (25%), Positives = 129/342 (37%), Gaps = 51/342 (14%)

Query: 9    EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
            E     + T   +S   ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 1939 ESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 1998

Query: 62   SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQL 119
            S    GT V      T  L    TT+    G+++T    GS  T+ G S +S   +S   
Sbjct: 1999 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGLSEKSTTFHS--- 2054

Query: 120  YPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY--SQTGQP---------YSLP 168
              S   P    +PA+ T S  + ++  S  +  + +T      T  P         +S P
Sbjct: 2055 --SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 2112

Query: 169  TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTP--QPGQTPYSYQMPGSSFAPSS 226
                  +LPA  T SG SQ  +   S     SPG +     PG T         SF   S
Sbjct: 2113 GSTDTTLLPASTTTSGPSQESTTSHS-----SPGSTDTALSPGST------TALSFGQES 2161

Query: 227  TIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 286
            T + ++  S  T        +P  T       A     S+ G+  T+ + A    SSTS 
Sbjct: 2162 TTFHSSPGSTHTTL------FPDSTTSSGIVEASTRVHSSTGSPRTTLSPA----SSTSP 2211

Query: 287  YQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTC--RSSGS 326
                ES    T+      T   PST    ++E T   RS GS
Sbjct: 2212 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 2253



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 78/377 (20%), Positives = 126/377 (33%), Gaps = 67/377 (17%)

Query: 9    EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
            E     + T   +S   ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 4772 ESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHS 4831

Query: 62   SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYP 121
            S  TNG         T    +  TT     G+++T   S  T+ G S +S   YS    P
Sbjct: 4832 SPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSP 4891

Query: 122  SKPYPHILSTPAAQTMSAYAGQ-------------------TQYSGMQQPAVYTAYSQTG 162
             +       +PA+ T S+ +G+                   T  SG+ Q +  T +S+ G
Sbjct: 4892 DQTL-----SPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQEST-TFHSKPG 4945

Query: 163  Q---------------------PYSLPTYDLGVMLPAIKTESGLSQTQSPLQSG------ 195
                                  P+S P   L  + PA  T  GLS+  +   S       
Sbjct: 4946 STETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTET 5005

Query: 196  -CLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 254
               S+S   S      TP+    PG +            +   +    S  D    T   
Sbjct: 5006 TAFSHSNTMSIHSQQSTPFP-DSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLP 5064

Query: 255  QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIK 314
                A          Y++       +P+ T+ +    S  GLT +   F T  S ++ I 
Sbjct: 5065 ARSTASDLVGEPTTFYISP------SPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIV 5118

Query: 315  DLDERTCRSSGSKSRGR 331
              +     + G    G+
Sbjct: 5119 STESLETLAPGLCQEGQ 5135



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 76/340 (22%), Positives = 125/340 (36%), Gaps = 56/340 (16%)

Query: 19   SDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS----------TSVTTNGT 68
            S+ S + +SR       A P +      TPG S+   ++ SS           S TT+G 
Sbjct: 2074 SEESTTSHSRPGSTHTTAFPDSTT----TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 2129

Query: 69   GVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAH--------------Q 114
                    + P  S++T  + G     +F G   T+   SP S H              +
Sbjct: 2130 SQESTTSHSSP-GSTDTALSPGSTTALSF-GQESTTFHSSPGSTHTTLFPDSTTSSGIVE 2187

Query: 115  YSPQLYPSKPYPHILSTPAAQTMSAYAGQTQ---------YSGMQQPAVYTAYSQTGQPY 165
             S +++ S   P    +PA+ T     G++          ++    P+  TA  +    Y
Sbjct: 2188 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 2247

Query: 166  -----SLPTYDLGVMLPAIKTESGLSQTQ-----SPLQSGCLSYSPGFSTPQPGQTPYSY 215
                 S PT       PA  T SG S+       SP  SG    S   +T   G++  S 
Sbjct: 2248 HRSPGSTPT----THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 2303

Query: 216  QMPGSS---FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMT 272
              PGS+     P ST     S +++T +S  +    + +            ++T  +   
Sbjct: 2304 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG 2363

Query: 273  SNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 312
            S ++     S+T+    +ES    ++ PG  +T   P TP
Sbjct: 2364 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTP 2403



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 72/300 (24%), Positives = 114/300 (38%), Gaps = 44/300 (14%)

Query: 40   TLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--F 97
            TL G   TP  S  EKS    TS  +    +S     +  ++   +T+ +  G+  T  F
Sbjct: 2983 TLPGSPTTPSLS--EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAF 3040

Query: 98   TGSVITSSGYSPRSAHQYSPQ------LYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQ 151
              S  T+SG S      +S Q      L P       L   +  T  +  G T+ + +  
Sbjct: 3041 PDST-TTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQST-TFHSSPGDTETTLLPD 3098

Query: 152  PAVYTAYSQTGQPYSLPTYDLGVML-PAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQ 210
              + +   +   P    T  L   L PA  T +GL +  +  QS   S     +TP P  
Sbjct: 3099 DTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD---TTPSP-- 3153

Query: 211  TPYSYQMPGSSFAP---SSTIYANNSVSNSTNFSGSQQD----------YPSYTAFGQNQ 257
                   PG++ AP   S+T ++  S + +T+FS S             + S  A G   
Sbjct: 3154 -------PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTAL 3206

Query: 258  YAQYYSASTYGAYMTSNNTADGT------PSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
            +    + S      T++  + G+      P ST+T  L E      + P   DT  SP++
Sbjct: 3207 FPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 3266



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 80/348 (22%), Positives = 134/348 (38%), Gaps = 59/348 (16%)

Query: 6    DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTT 65
            DL E+S       +    S  S   ++    S  + + G  TP  S+L  S+  +T++  
Sbjct: 1379 DLGEES-------TTFPSSSGSTGTKLSPARSTTSGLVGESTP--SRLSPSSTETTTLPG 1429

Query: 66   NGTGVSLLAVKTEPLNSSETTATTGDGALD-TFTGSVITSSGYSPRSAHQYS-PQLYPSK 123
            + T        T  L+   TT  T   + D T + +  TSSG S  S+  +S P    + 
Sbjct: 1430 SPT--------TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTT 1481

Query: 124  PYPHILSTP--AAQTMSAYAGQTQYSGMQQPAVYTAYS---QTGQPYSLPTYDLGVMLPA 178
             +P   +T   + +  ++++ Q        P   TA S   Q+   +S P      +LP 
Sbjct: 1482 AFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 1541

Query: 179  IKTESGLSQTQSPLQSGCLSY----SPGFSTPQ------------PGQTPYSYQMPGSSF 222
                SGL +  +P  S   S     +P  ST              P  +  +   PG++ 
Sbjct: 1542 DTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTA 1601

Query: 223  AP---SSTIYANNSVSNSTNFSGSQQD----------YPSYTAFGQNQYAQYYSASTYGA 269
            AP   S+T ++  S + +T+FS S             + S  A G   +    + S    
Sbjct: 1602 APVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG 1661

Query: 270  YMTSNNTADGT------PSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
              T++  + G+      P ST+T  L E      + P   DT  SP++
Sbjct: 1662 EPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 1709



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 72/286 (25%), Positives = 109/286 (38%), Gaps = 54/286 (18%)

Query: 50   SSKLEKSNLSSTSVTTNG-TGVSLLAVK--TEPLNSSETTATTGDGALDT--FTGSVITS 104
            S+ L +S  S+T  ++ G TG +L   +  T  L    TT+    G+ +T    GS  T+
Sbjct: 1626 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST-TT 1684

Query: 105  SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQP 164
            +G S +S   YS     S   P    +PA+ T S  + ++           T++S+ G  
Sbjct: 1685 AGLSEKSTTFYS-----SPRSPDTTLSPASTTSSGVSEEST----------TSHSRPGST 1729

Query: 165  YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS--TPQPGQTPYSYQMPGSSF 222
            ++          P   T  G+SQ  +   S     SPG +  T  PG T        SS 
Sbjct: 1730 HT-------TAFPGSTTMPGVSQESTASHS-----SPGSTDTTLSPGSTT------ASSL 1771

Query: 223  APSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPS 282
             P ST + ++  S  T            TA G  + +    +ST   + T +     T  
Sbjct: 1772 GPESTTFHSSPGSTETTLLPDNT-----TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ 1826

Query: 283  STSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKS 328
              ST           + P   DTM +P T      E +  S GS S
Sbjct: 1827 GESTT--------FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS 1864



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 68/284 (23%), Positives = 105/284 (36%), Gaps = 34/284 (11%)

Query: 36   ASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALD 95
            AS HT +   D+  S   E+S     S  +  TG+    + T  L    TT  +  G+  
Sbjct: 1337 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTG 1395

Query: 96   T-FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAV 154
            T  + +  T+SG    S              P  LS  + +T +     T  S  ++   
Sbjct: 1396 TKLSPARSTTSGLVGEST-------------PSRLSPSSTETTTLPGSPTTPSLSEKSTT 1442

Query: 155  YTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQS-----PLQSGCLSYSPGFSTPQPG 209
            +         Y+ P      + PA  T SG+S+  S     P  +   ++    +T    
Sbjct: 1443 F---------YTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLS 1493

Query: 210  QTPY-SYQMPGSSFA---PSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSAS 265
            Q P  S+   GS+ A   P ST  A++    ST F  S  D  +         +    AS
Sbjct: 1494 QEPTTSHSSQGSTEATLSPGSTT-ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAS 1552

Query: 266  TYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSP 309
            T     T +     TP+S+++  LQE      + P   DT  SP
Sbjct: 1553 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 1596



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 74/306 (24%), Positives = 115/306 (37%), Gaps = 37/306 (12%)

Query: 4    SQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSV 63
            S D        T    +VS + +SR       ++P T      T    + E+S    +S 
Sbjct: 4229 SSDTTPSPPSTTAVPVEVSTTYHSRPS-----STPTTHFSASSTT-LGRSEESTTVHSSP 4282

Query: 64   TTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQLYP 121
               GT +      T  L    TT+    G+ +T    GS  T++G S +S   YS     
Sbjct: 4283 GATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST-TTAGLSEKSTTFYS----- 4336

Query: 122  SKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY--SQTGQP---------YSLPTY 170
            S   P    +PA+ T S  + ++  S  +  +++T    S T  P         +S P  
Sbjct: 4337 SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGS 4396

Query: 171  DLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS--TPQPGQTPYSYQMPGSSFAPSSTI 228
                + P   T S L    +   S     SPG +  T  P  T  S  +  S+   SST 
Sbjct: 4397 TDTTLSPGSTTASSLGPESTTFHS-----SPGSTETTLLPDNTTASGLLEASTPVHSSTG 4451

Query: 229  YANNSVS--NSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 286
              + ++S   ST   G    + S+        A     +T  A++  + T+ G+PSST T
Sbjct: 4452 SPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP---PTTTSAFVELSTTSHGSPSSTPT 4508

Query: 287  YQLQES 292
                 S
Sbjct: 4509 THFSAS 4514



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 68/281 (24%), Positives = 100/281 (35%), Gaps = 28/281 (9%)

Query: 36   ASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALD 95
            AS HT +   D+  S   E+S     S  +  TG+    + T  L    TT  +  G+  
Sbjct: 2894 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTG 2952

Query: 96   T-FTGSVITSSGYSPRSA-HQYSPQLYPSKPYPHILSTPAAQTMSA--YAGQTQYSGMQQ 151
            T  + +  T+SG    S   + SP    +   P   +TP+    S   Y           
Sbjct: 2953 TTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 3012

Query: 152  PAVYTAYS---QTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQP 208
            PA  T+     ++   +S P        P   T SGLSQ             P  S    
Sbjct: 3013 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQ------------EPTASHSSQ 3060

Query: 209  GQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYG 268
            G T        ++ +P ST  A++    ST F  S  D  +         +    AST  
Sbjct: 3061 GSTE-------ATLSPGSTT-ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 3112

Query: 269  AYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSP 309
               T +     TP+S+++  LQE      + P   DT  SP
Sbjct: 3113 HSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 3153



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 68/281 (24%), Positives = 100/281 (35%), Gaps = 28/281 (9%)

Query: 36   ASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALD 95
            AS HT +   D+  S   E+S     S  +  TG+    + T  L    TT  +  G+  
Sbjct: 3977 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTG 4035

Query: 96   T-FTGSVITSSGYSPRSA-HQYSPQLYPSKPYPHILSTPAAQTMSA--YAGQTQYSGMQQ 151
            T  + +  T+SG    S   + SP    +   P   +TP+    S   Y           
Sbjct: 4036 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 4095

Query: 152  PAVYTAYS---QTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQP 208
            PA  T+     ++   +S P        P   T SGLSQ             P  S    
Sbjct: 4096 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQ------------EPTTSHSSQ 4143

Query: 209  GQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYG 268
            G T        ++ +P ST  A++    ST F  S  D  +         +    AST  
Sbjct: 4144 GSTE-------ATLSPGSTT-ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPT 4195

Query: 269  AYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSP 309
               T +     TP+S+++  LQE      + P   DT  SP
Sbjct: 4196 HSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSP 4236



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 70/290 (24%), Positives = 109/290 (37%), Gaps = 24/290 (8%)

Query: 40   TLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--F 97
            TL G   TP  S  EKS    TS  +    +S     +  ++   +T+ +  G+  T  F
Sbjct: 4066 TLPGSPTTPSLS--EKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAF 4123

Query: 98   TGSVITSSGYSPRSAHQYSPQ------LYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQ 151
              S  T+SG S      +S Q      L P       L   +  T  +  G T+ + +  
Sbjct: 4124 PDST-TTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQST-TFHSSPGDTETTLLPD 4181

Query: 152  PAVYTAYSQTGQPYSLPTYDLGVML-PAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQ 210
              + +   +   P    T  L   L PA  T +GL +  +  QS   S     S P    
Sbjct: 4182 DTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTA 4241

Query: 211  TPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAY 270
             P        S  PSST   + S S ST    S++    +++ G    A + + S     
Sbjct: 4242 VPVEVSTTYHS-RPSSTPTTHFSAS-STTLGRSEESTTVHSSPGATGTALFPTRSATSVL 4299

Query: 271  M---TSNNTADGT------PSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
            +   T++  + G+      P ST+T  L E      + P   DT  SP++
Sbjct: 4300 VGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 4349



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 69/315 (21%), Positives = 116/315 (36%), Gaps = 39/315 (12%)

Query: 9    EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
            E +   + T   +S + ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 4579 ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 4638

Query: 62   SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQL 119
            S    GT V      T  L    TT+    G+++T    GS  T       +    SP  
Sbjct: 4639 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSS 4698

Query: 120  YP-------------SKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 166
             P             S+    + S+P A   +    ++  SG+ + +  TAY      +S
Sbjct: 4699 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEES--TAY------HS 4750

Query: 167  LPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSS 226
             P     +  P   T SG S+      S   S +   S+P P  T    + P S  +   
Sbjct: 4751 SPGSTQTMHFPESSTASGRSEESRTSHS---STTHTISSP-PSTTSALVEEPTSYHSSPG 4806

Query: 227  TIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 286
            +I   +   +ST    S++   S+++   N      +  T     TS   A+ T    S 
Sbjct: 4807 SIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFT-----TSGRIAESTTFYISP 4861

Query: 287  YQLQESLPGLTNQPG 301
              ++ +L      PG
Sbjct: 4862 GSMETTLASTATTPG 4876



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 68/316 (21%), Positives = 113/316 (35%), Gaps = 49/316 (15%)

Query: 36   ASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALD 95
            AS HT +   D+  S   E+S     S  +  TG+    + T  L    TT  +  G+  
Sbjct: 2420 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTG 2478

Query: 96   T-FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAV 154
            T  + +  T+SG    S              P  LS  + +T +     T  S  ++   
Sbjct: 2479 TTLSPARSTTSGLVGEST-------------PSRLSPSSTETTTLPGSPTTPSLSEKSTT 2525

Query: 155  YTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS 214
            +         Y+ P      + PA  T SG+S+  S   S            QPG T ++
Sbjct: 2526 F---------YTSPRSPDATLSPATTTSSGVSEESSTSHS------------QPGST-HT 2563

Query: 215  YQMPGSSFAPSSTIYANNSVSN-----------STNFSG-SQQDYPSYTAFGQNQYAQYY 262
               P S+  P  + ++  S S+           ST  SG SQ+   S+++ G    A   
Sbjct: 2564 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSP 2623

Query: 263  SASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCR 322
             ++T  ++   + T   +P ST T    +S               S  +P   L   +  
Sbjct: 2624 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 2683

Query: 323  SSGSKSRGRGRKNNPS 338
            S G +      + +P+
Sbjct: 2684 SPGLQGESTTFQTHPA 2699



 Score = 38.1 bits (87), Expect = 0.024
 Identities = 63/295 (21%), Positives = 104/295 (35%), Gaps = 15/295 (5%)

Query: 26   NSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSET 85
            +S SME   L    T  G  +   +     S+  +T  + + T +      T   +S   
Sbjct: 4667 SSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 4726

Query: 86   TATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYA-GQT 144
            TATT   A  T +G V  S+ Y        SP    +  +P   +       S  +   T
Sbjct: 4727 TATTPSPARSTTSGLVEESTAYHS------SPGSTQTMHFPESSTASGRSEESRTSHSST 4780

Query: 145  QYSGMQQPAVYTAYSQTGQPY-SLPTYDLGVMLPAIKTESGLSQTQ-----SPLQSGCLS 198
             ++    P+  +A  +    Y S P        P   T SG S+       SP  +G   
Sbjct: 4781 THTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITP 4840

Query: 199  YSPGFSTP-QPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQ 257
                F+T  +  ++   Y  PGS     ++      +S  +    S    P  T    + 
Sbjct: 4841 LPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASM 4900

Query: 258  YAQYYSASTYGAYMTSNNT-ADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
             +   S      Y  + +T     P+ST+T  L +      ++PG  +T  SP +
Sbjct: 4901 TSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGS 4955



 Score = 37.4 bits (85), Expect = 0.041
 Identities = 58/271 (21%), Positives = 101/271 (37%), Gaps = 30/271 (11%)

Query: 37   SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
            S HT    G T      ++S  S +S  +  T +S  +     L    TT  +G G+ +T
Sbjct: 3285 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTET 3344

Query: 97   FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQ----- 151
                 +     +     + S  ++ S   PH   +PA  T       T  S         
Sbjct: 3345 ----TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 3400

Query: 152  --PAVYTAY-----SQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS 204
              P   +A+     +  G P S PT        A  T  G S+  + + S  ++ +   +
Sbjct: 3401 APPTTTSAFVELSTTSHGSPSSTPT----THFSASSTTLGRSEESTTVHSSPVATA---T 3453

Query: 205  TPQPGQTPYSYQMPGSS---FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQY 261
            TP P ++  S  +  S+    +P ST   +   S++T+  G +    S T+     +   
Sbjct: 3454 TPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE----STTSHSSTTHTIS 3509

Query: 262  YSASTYGAYMTSNNTADGTPSSTSTYQLQES 292
             + ST  A +    +   +P ST+T    +S
Sbjct: 3510 SAPSTTSALVEEPTSYHSSPGSTATTHFPDS 3540



 Score = 36.6 bits (83), Expect = 0.070
 Identities = 71/342 (20%), Positives = 122/342 (35%), Gaps = 42/342 (12%)

Query: 37   SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
            SP T +    +       +S    T   +  T  S  +  T P+  S T   +      T
Sbjct: 3755 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 3814

Query: 97   FTGSVITSSGYSPRSAHQYSPQ----LYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQP 152
               +  T+SG+S +S   +S        PS  +        + T     G T+ + +   
Sbjct: 3815 HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 3874

Query: 153  AVYTAYSQTGQP-YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQT 211
                  S+     YS P      + PA  T  G+ +  +  +S            QPG T
Sbjct: 3875 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS------------QPGST 3922

Query: 212  -----PYSYQMPGSSFAPSSTIYANNSVS-------NSTNFSGSQQDYPSYTAFGQNQYA 259
                 P S   PG S   S+T+Y+++  S        ST  S  +++  ++ +   + + 
Sbjct: 3923 HSTVSPASTTTPGLS-EESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHT 3981

Query: 260  QYYSASTYGAYMTSNNTA---------DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSP- 309
              ++  +  + +T  +TA          G P++ +T  L E      +  G   T  SP 
Sbjct: 3982 TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPA 4041

Query: 310  -STPIKDLDERT-CRSSGSKSRGRGRKNNPSPPPDSDLERVF 349
             ST    + E T  R S S +       +P+ P  S+    F
Sbjct: 4042 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF 4083



 Score = 36.2 bits (82), Expect = 0.091
 Identities = 68/321 (21%), Positives = 113/321 (35%), Gaps = 39/321 (12%)

Query: 37   SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
            SP T +    +       +S    T   +  T  S  +  T P+  S T   +      T
Sbjct: 1115 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 1174

Query: 97   FTGSVITSSGYSPRSAHQYSPQ----LYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQP 152
               +  T+SG+S +S   +S        PS  +        + T     G T+ + +   
Sbjct: 1175 HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 1234

Query: 153  AVYTAYSQTGQP-YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQT 211
                  S+     YS P      + PA  T  G+ +  +  +S            QPG T
Sbjct: 1235 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS------------QPGST 1282

Query: 212  -----PYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS--A 264
                 P S   PG S   S+T+Y+++  S  T        + + T+    +   ++S  A
Sbjct: 1283 HSTVSPASTTTPGLS-EESTTVYSSSRGSTETTVF----PHSTTTSVHGEEPTTFHSRPA 1337

Query: 265  STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSS 324
            ST+    T ++T  G    ++ +      PG    P    T    +    DL E +  + 
Sbjct: 1338 STHTTLFTEDSTTSGLTEESTAF------PG---SPASTQTGLPATLTTADLGEES-TTF 1387

Query: 325  GSKSRGRGRKNNPSPPPDSDL 345
             S S   G K +P+    S L
Sbjct: 1388 PSSSGSTGTKLSPARSTTSGL 1408



 Score = 36.2 bits (82), Expect = 0.091
 Identities = 68/323 (21%), Positives = 114/323 (35%), Gaps = 44/323 (13%)

Query: 37   SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
            S HT    G T      ++S  S +S  +  T +S  +     L    TT  +  G+ +T
Sbjct: 1728 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTET 1787

Query: 97   FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS------GMQ 150
                 +     +     + S  ++ S   PH   +PA  T       T  S       M 
Sbjct: 1788 ----TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1843

Query: 151  QPAVYT------AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS 204
             P   T      + +  G P S PT        A  T  G S+  + + S  ++ +   +
Sbjct: 1844 APPTTTSAFVELSTTSHGSPSSTPT----THFSASSTTLGRSEESTTVHSSPVATA---T 1896

Query: 205  TPQPGQTPYS---------YQMPGSS----FAPSSTIYANNSVSNSTNFSGSQ--QDYPS 249
            TP P ++  S         +  PGS+    F  SST    +  S +++ S +      PS
Sbjct: 1897 TPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS 1956

Query: 250  YTAFGQNQYAQYYSA--STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTM- 306
             T+    +   Y+S+  ST   +   ++T  G    ++     +   G    P    T  
Sbjct: 1957 TTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSV 2016

Query: 307  ---QSPSTPIKDLDERTCRSSGS 326
               +S ++PI      T    GS
Sbjct: 2017 LLGESTTSPISSGSMETTALPGS 2039



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 71/342 (20%), Positives = 121/342 (35%), Gaps = 42/342 (12%)

Query: 37   SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
            SP T +    +       +S    T   +  T  S  +  T P+  S T   +      T
Sbjct: 2672 SPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 2731

Query: 97   FTGSVITSSGYSPRSAHQYSPQ----LYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQP 152
               +  T+SG+S +S   +S        PS  +        + T     G T+ + +   
Sbjct: 2732 HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 2791

Query: 153  AVYTAYSQTGQP-YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQT 211
                  S+     YS P      + PA  T  G+ +  +  +S            QPG T
Sbjct: 2792 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS------------QPGST 2839

Query: 212  -----PYSYQMPGSSFAPSSTIYANNSVS-------NSTNFSGSQQDYPSYTAFGQNQYA 259
                 P S   PG S   S+T+Y+++  S        ST  S   ++  ++ +   + + 
Sbjct: 2840 HSTVSPASTTTPGLS-EESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHT 2898

Query: 260  QYYSASTYGAYMTSNNTA---------DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSP- 309
              ++  +  + +T  +TA          G P++ +T  L E      +  G   T  SP 
Sbjct: 2899 TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPA 2958

Query: 310  -STPIKDLDERT-CRSSGSKSRGRGRKNNPSPPPDSDLERVF 349
             ST    + E T  R S S +       +P+ P  S+    F
Sbjct: 2959 RSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTF 3000



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 64/312 (20%), Positives = 109/312 (34%), Gaps = 19/312 (6%)

Query: 15   TCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLA 74
            T T S VS+  ++   +     S HT      T  S   ++   S +S  +    +S  +
Sbjct: 4098 TTTSSGVSEESSTSHSQP---GSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGS 4154

Query: 75   VKTEPLNSSETTATTGDGAL-------DTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPH 127
                 L    TT  +  G         DT T  ++ +S  +  S       L P+     
Sbjct: 4155 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214

Query: 128  ILSTPAAQTMS-AYAGQTQYSGMQQPAVYTAYSQT--GQPYSLPTYDLGVMLPAI-KTES 183
             L   +    S   +  T  S     AV    S T   +P S PT         + ++E 
Sbjct: 4215 GLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 4274

Query: 184  GLSQTQSPLQSGCLSYSPGFSTP----QPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTN 239
              +   SP  +G   +    +T     +P  +P S     ++  P ST  A  S  ++T 
Sbjct: 4275 STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTF 4334

Query: 240  FSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQ 299
            +S  +    + +            ++T  +   S +T    PSST+   + +      + 
Sbjct: 4335 YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTT-AFPSSTTMPGVSQESTASHSS 4393

Query: 300  PGEFDTMQSPST 311
            PG  DT  SP +
Sbjct: 4394 PGSTDTTLSPGS 4405


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 76/317 (23%), Positives = 125/317 (39%), Gaps = 45/317 (14%)

Query: 40   TLVGGGDTPGSSKLEKS----------NLSSTSVTTNGTGVSLLAVKTEP--LNSSETTA 87
            TL G   TPG S+   +           LS  S+T+ G G      +++P   +S+ + A
Sbjct: 717  TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 776

Query: 88   TTGDGALDTFTGSVITSSGYSPRSA---HQYSPQLYPSKPYPHILSTPAAQTMSAYAGQT 144
            +T    L   + +V +SS  S  +    H  +  ++  +P     S PA+   + +   +
Sbjct: 777  STTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTT-FHSRPASTHTTLFTEDS 835

Query: 145  QYSGMQQPAVY----TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYS 200
              SG+ + +       A +QTG P +L T DLG       + SG + T+        S  
Sbjct: 836  TTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGL 895

Query: 201  PGFSTP---QPGQTPYSYQMPGSSFAP-----SSTIY---------------ANNSVSNS 237
             G STP    P  T  +  +PGS   P     S+T Y                ++ VS  
Sbjct: 896  VGESTPSRLSPSSTE-TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE 954

Query: 238  TNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-ADGTPSSTSTYQLQESLPGL 296
            ++ S SQ      TAF  +      S     ++ +  +T A  +P ST+   L +     
Sbjct: 955  SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTF 1014

Query: 297  TNQPGEFDTMQSPSTPI 313
             + PG+ +T   P   I
Sbjct: 1015 HSSPGDTETTLLPDDTI 1031



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 89/340 (26%), Positives = 129/340 (37%), Gaps = 47/340 (13%)

Query: 9   EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
           E +   + T   +S + ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 343 ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 402

Query: 62  SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQL 119
           S    GT V      T  L    TT+    G+++T    GS  T+ G S RS   +S   
Sbjct: 403 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGLSERSTTFHS--- 458

Query: 120 YPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY--SQTGQP---------YSLP 168
             S   P    +PA+ T S  + ++  S  +  + +T      T  P         +S P
Sbjct: 459 --SPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 516

Query: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 228
                 +LPA  T SG SQ  +   S   S     S   PG T         SF   ST 
Sbjct: 517 GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALS---PGST------TALSFGQESTT 567

Query: 229 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 288
           + +N  S  T        +P  T       A     S+ G+  T+ + A    SSTS   
Sbjct: 568 FHSNPGSTHTTL------FPDSTTSSGIVEASTRVHSSTGSPRTTLSPA----SSTSPGL 617

Query: 289 LQESLPGLTNQPGEFDTMQSPSTPIKDLDERTC--RSSGS 326
             ES    T+      T   PST    ++E T   RS GS
Sbjct: 618 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 657



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 80/348 (22%), Positives = 134/348 (38%), Gaps = 59/348 (16%)

Query: 6    DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTT 65
            DL E+S       +    S  S   ++    S  + + G  TP  S+L  S+  +T++  
Sbjct: 866  DLGEES-------TTFPSSSGSTGTKLSPARSTTSGLVGESTP--SRLSPSSTETTTLPG 916

Query: 66   NGTGVSLLAVKTEPLNSSETTATTGDGALD-TFTGSVITSSGYSPRSAHQYS-PQLYPSK 123
            + T        T  L+   TT  T   + D T + +  TSSG S  S+  +S P    + 
Sbjct: 917  SPT--------TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTT 968

Query: 124  PYPHILSTP--AAQTMSAYAGQTQYSGMQQPAVYTAYS---QTGQPYSLPTYDLGVMLPA 178
             +P   +T   + +  ++++ Q        P   TA S   Q+   +S P      +LP 
Sbjct: 969  AFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPD 1028

Query: 179  IKTESGLSQTQSPLQSGCLSY----SPGFSTPQ------------PGQTPYSYQMPGSSF 222
                SGL +  +P  S   S     +P  ST              P  +  +   PG++ 
Sbjct: 1029 DTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTA 1088

Query: 223  AP---SSTIYANNSVSNSTNFSGSQQD----------YPSYTAFGQNQYAQYYSASTYGA 269
            AP   S+T ++  S + +T+FS S             + S  A G   +    + S    
Sbjct: 1089 APVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVG 1148

Query: 270  YMTSNNTADGT------PSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
              T++  + G+      P ST+T  L E      + P   DT  SP++
Sbjct: 1149 EPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 1196



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 72/286 (25%), Positives = 109/286 (38%), Gaps = 54/286 (18%)

Query: 50   SSKLEKSNLSSTSVTTNG-TGVSLLAVK--TEPLNSSETTATTGDGALDT--FTGSVITS 104
            S+ L +S  S+T  ++ G TG +L   +  T  L    TT+    G+ +T    GS  T+
Sbjct: 1113 STTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST-TT 1171

Query: 105  SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQP 164
            +G S +S   YS     S   P    +PA+ T S  + ++           T++S+ G  
Sbjct: 1172 AGLSEKSTTFYS-----SPRSPDTTLSPASTTSSGVSEEST----------TSHSRPGST 1216

Query: 165  YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS--TPQPGQTPYSYQMPGSSF 222
            ++          P   T  G+SQ  +   S     SPG +  T  PG T        SS 
Sbjct: 1217 HT-------TAFPGSTTMPGVSQESTASHS-----SPGSTDTTLSPGSTT------ASSL 1258

Query: 223  APSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPS 282
             P ST + ++  S  T            TA G  + +    +ST   + T +     T  
Sbjct: 1259 GPESTTFHSSPGSTETTLLPDNT-----TASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ 1313

Query: 283  STSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKS 328
              ST           + P   DTM +P T      E +  S GS S
Sbjct: 1314 GESTT--------FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS 1351



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 68/284 (23%), Positives = 105/284 (36%), Gaps = 34/284 (11%)

Query: 36   ASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALD 95
            AS HT +   D+  S   E+S     S  +  TG+    + T  L    TT  +  G+  
Sbjct: 824  ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPA-TLTTADLGEESTTFPSSSGSTG 882

Query: 96   T-FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAV 154
            T  + +  T+SG    S              P  LS  + +T +     T  S  ++   
Sbjct: 883  TKLSPARSTTSGLVGEST-------------PSRLSPSSTETTTLPGSPTTPSLSEKSTT 929

Query: 155  YTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQS-----PLQSGCLSYSPGFSTPQPG 209
            +         Y+ P      + PA  T SG+S+  S     P  +   ++    +T    
Sbjct: 930  F---------YTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLS 980

Query: 210  QTPY-SYQMPGSSFA---PSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSAS 265
            Q P  S+   GS+ A   P ST  A++    ST F  S  D  +         +    AS
Sbjct: 981  QEPTTSHSSQGSTEATLSPGSTT-ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEAS 1039

Query: 266  TYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSP 309
            T     T +     TP+S+++  LQE      + P   DT  SP
Sbjct: 1040 TPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 1083



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 63/298 (21%), Positives = 106/298 (35%), Gaps = 40/298 (13%)

Query: 37   SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
            S HT    G T      ++S  S +S  +  T +S  +     L    TT  +  G+ +T
Sbjct: 1215 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTET 1274

Query: 97   FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS------GMQ 150
                 +     +     + S  ++ S   PH   +PA  T       T  S       M 
Sbjct: 1275 ----TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1330

Query: 151  QPAVYT------AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS 204
             P   T      + +  G P S PT        A  T  G S+  + + S  ++ +   +
Sbjct: 1331 APPTTTSAFVELSTTSHGSPSSTPT----THFSASSTTLGRSEESTTVHSSPVATA---T 1383

Query: 205  TPQPGQTPYS---------YQMPGSS----FAPSSTIYANNSVSNSTNFSGSQ--QDYPS 249
            TP P ++  S         +  PGS+    F  SST    +  S +++ S +      PS
Sbjct: 1384 TPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS 1443

Query: 250  YTAFGQNQYAQYYSA--STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDT 305
             T+    +   Y+S+  S    +   ++T  G    ++         G+T  P  F T
Sbjct: 1444 TTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 1501



 Score = 36.2 bits (82), Expect = 0.091
 Identities = 68/321 (21%), Positives = 113/321 (35%), Gaps = 39/321 (12%)

Query: 37  SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
           SP T +    +       +S    T   +  T  S  +  T P+  S T   +      T
Sbjct: 602 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 661

Query: 97  FTGSVITSSGYSPRSAHQYSPQ----LYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQP 152
              +  T+SG+S +S   +S        PS  +        + T     G T+ + +   
Sbjct: 662 HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGS 721

Query: 153 AVYTAYSQTGQP-YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQT 211
                 S+     YS P      + PA  T  G+ +  +  +S            QPG T
Sbjct: 722 TTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS------------QPGST 769

Query: 212 -----PYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS--A 264
                P S   PG S   S+T+Y+++  S  T        + + T+    +   ++S  A
Sbjct: 770 HSTVSPASTTTPGLS-EESTTVYSSSRGSTETTVF----PHSTTTSVHGEEPTTFHSRPA 824

Query: 265 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSS 324
           ST+    T ++T  G    ++ +      PG    P    T    +    DL E +  + 
Sbjct: 825 STHTTLFTEDSTTSGLTEESTAF------PG---SPASTQTGLPATLTTADLGEES-TTF 874

Query: 325 GSKSRGRGRKNNPSPPPDSDL 345
            S S   G K +P+    S L
Sbjct: 875 PSSSGSTGTKLSPARSTTSGL 895


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 66/255 (25%), Positives = 97/255 (38%), Gaps = 27/255 (10%)

Query: 42   VGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLN---SSETTATTGDGALDTFT 98
            VG G TPG++    S  S  S  + G   +       P +   SS    + G     +++
Sbjct: 1535 VGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYS 1594

Query: 99   GSVITSSGYSPRSAHQYSPQ---LYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 155
                TS  Y PRS   Y+PQ     P+ P     S   + T   Y+  +       P+  
Sbjct: 1595 P---TSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPS-- 1649

Query: 156  TAYSQTGQPYS--LPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPY 213
              YS T   YS   P+Y      P   + S  S + SP        SP +S   P  +P 
Sbjct: 1650 --YSPTSPSYSPTSPSYS-----PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1702

Query: 214  S--YQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYM 271
            S  Y     S++P+S  Y+  S S S          PSY+    N     YS ++     
Sbjct: 1703 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPN-----YSPTSPNYTP 1757

Query: 272  TSNNTADGTPSSTST 286
            TS + +  +PS + T
Sbjct: 1758 TSPSYSPTSPSYSPT 1772



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 57/220 (25%), Positives = 84/220 (38%), Gaps = 24/220 (10%)

Query: 103  TSSGYSPRSAHQY--SPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPA---VYTA 157
            TS  YSP S +    SP   P+ P     S   + T  +Y+  +       P+      +
Sbjct: 1625 TSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1684

Query: 158  YSQTGQPYS--LPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS- 214
            YS T   YS   P+Y      P   + S  S + SP        SP +S   P  +P S 
Sbjct: 1685 YSPTSPSYSPTSPSYS-----PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1739

Query: 215  -YQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTS 273
             Y     +++P+S  Y   S S S          P+YT    N     YS ++     TS
Sbjct: 1740 SYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPN-----YSPTSPSYSPTS 1794

Query: 274  NNTADGTPS-STSTYQLQESLPGLTNQPGEFDTMQSPSTP 312
             + +  +PS S S+ +     P  T     +    SPS+P
Sbjct: 1795 PSYSPTSPSYSPSSPRYTPQSPTYTPSSPSY----SPSSP 1830



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 51/204 (25%), Positives = 73/204 (35%), Gaps = 14/204 (6%)

Query: 57   NLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQY- 115
            N S TS + + T  S          +S + + T      T      TS  YSP S     
Sbjct: 1635 NYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1694

Query: 116  -SPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPA---VYTAYSQTGQPYS--LPT 169
             SP   P+ P     S   + T  +Y+  +       P+      +YS T   YS   P 
Sbjct: 1695 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPN 1754

Query: 170  YDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS--YQMPGSSFAPSST 227
            Y      P   + S  S + SP        SP +S   P  +P S  Y     S++PSS 
Sbjct: 1755 YT-----PTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSP 1809

Query: 228  IYANNSVSNSTNFSGSQQDYPSYT 251
             Y   S + + +        PSY+
Sbjct: 1810 RYTPQSPTYTPSSPSYSPSSPSYS 1833



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 48/200 (24%), Positives = 70/200 (35%), Gaps = 21/200 (10%)

Query: 103  TSSGYSPRSAHQY--SPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQ 160
            TS  YSP S +    SP   P+ P     S   + T  +Y+  +     Q P  YT  S 
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPT-YTPSSP 1823

Query: 161  TGQPYSLPTYD--LGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS---- 214
            +  P S P+Y        P   + S  S   +P        SP +S   P  +P S    
Sbjct: 1824 SYSPSS-PSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYS 1882

Query: 215  -----YQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGA 269
                 Y     +++P+S +Y   S   S          P Y+             STY  
Sbjct: 1883 PTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTY-- 1940

Query: 270  YMTSNNTADGTPSSTSTYQL 289
                + T+ G   ++ TY L
Sbjct: 1941 ----SPTSPGYSPTSPTYSL 1956


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 92/310 (29%), Positives = 120/310 (38%), Gaps = 58/310 (18%)

Query: 83  SETTATTGDGALDTFTGSVI----TSSGY-SPRSAHQYSP--QLYPSKPYPHILSTPAAQ 135
           ++TTAT G  A  T  G       TS+GY +P +   YS   Q Y +  Y    +T    
Sbjct: 55  AQTTATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTAT-VTT 113

Query: 136 TMSAYAGQTQYSGMQQPAVYTAYSQTGQP-YSLPTYDLGVMLPAIKTESGLSQT----QS 190
           T ++YA Q+ Y    QPA Y AY Q  QP  + PT       P  +T    S T    Q 
Sbjct: 114 TQASYAAQSAYG--TQPA-YPAYGQ--QPAATAPTRPQDGNKPT-ETSQPQSSTGGYNQP 167

Query: 191 PLQSGCLSYS----PGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFS----- 241
            L  G  +YS    PG    QP   P SY  P S  +   T Y  +S S    +      
Sbjct: 168 SLGYGQSNYSYPQVPGSYPMQPVTAPPSYP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSY 226

Query: 242 GSQQDYPSYTAFGQNQYAQY------YS------ASTYGAYMTSNNTADGTPSSTSTYQL 289
           G Q  Y   +++GQ     Y      YS      +    +Y   ++     PSS   Y  
Sbjct: 227 GQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG- 285

Query: 290 QESLPGLTNQPGEFDTMQSPSTPIKDLD--ERTCRSSGSKSRGRGRK--------NNPSP 339
           QES  G  + PGE  +M  P    +     +R   S G +  GRG          N P  
Sbjct: 286 QES--GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGG 343

Query: 340 P----PDSDL 345
           P    PD DL
Sbjct: 344 PMDEGPDLDL 353


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 63/285 (22%), Positives = 112/285 (39%), Gaps = 40/285 (14%)

Query: 15   TCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT----PGSSKLEKSNLSSTSVTTNGTGV 70
            T T + ++ S ++ S     +  P TL   G T    P +     ++ + +S +TN T  
Sbjct: 1464 TPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPT 1523

Query: 71   SLLAVKT-----EPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPY 125
            SL +  +     E   +S TT T    +  T T    T+S  S R    ++    P+   
Sbjct: 1524 SLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS 1583

Query: 126  PHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL 185
            P   S+    T +++   T Y     P       QT  P  +P +   ++ P+  T + +
Sbjct: 1584 P--FSSTGPMTATSFKTTTTYPTPSHP-------QTTLPTHVPPFSTSLVTPS--THTVI 1632

Query: 186  SQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNF----S 241
            + T + + +    +S                MP  +  P +T+ A  S   +       S
Sbjct: 1633 TPTHAQMATSASIHS----------------MPTGTIPPPTTLKATGSTHTAPTMTLTTS 1676

Query: 242  GSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 286
            G+ Q   S      +     +++ST+ A  TS +T + TP+ TST
Sbjct: 1677 GTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTST 1721



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 60/259 (23%), Positives = 103/259 (39%), Gaps = 30/259 (11%)

Query: 47   TPGSSKLEKSNLSSTSVTTN--GTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITS 104
            T  +   E ++ S+T++T N   TG   + V T   + S ++ +T   +    +    TS
Sbjct: 1698 TSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSH---TS 1754

Query: 105  SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQ--TQYSGMQQPAVYTAYSQTG 162
            S + P      +  + P+        TP A T SA + +  T ++    P   T  S TG
Sbjct: 1755 STHHPEVTSTSTTSITPNHTSTGT-RTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTG 1813

Query: 163  QPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQ------PGQTPYS-- 214
             P +  ++      P        S   + L +   S+S    TP       P  T  +  
Sbjct: 1814 -PVTATSFQTTTTYPTP------SHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATS 1866

Query: 215  ---YQMPGSSFAPSSTIYANNSVSNSTNF----SGSQQDYPSYTAFGQNQYAQYYSASTY 267
               + MP  +  P +TI A  S   +       SG+ Q   S++    +    Y+++ST+
Sbjct: 1867 ASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTH 1926

Query: 268  GAYMTSNNTADGTPSSTST 286
               +T  +T + TP  TST
Sbjct: 1927 HPEVTPTSTTNITPKHTST 1945



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 74/314 (23%), Positives = 119/314 (37%), Gaps = 52/314 (16%)

Query: 15   TCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTN--GTGVSL 72
            T T S  SQS +S S      + P+       T  +   E +  S+T++T     TG   
Sbjct: 1896 TPTTSGTSQSPSSFSTAKTSTSLPY------HTSSTHHPEVTPTSTTNITPKHTSTGTRT 1949

Query: 73   LAVKTEPLNSSE-----TTATTGDGALDTFTGSVITSSGYS-----PRSAHQYSPQLYPS 122
                T   +SS      TT +   G+    +   +T++ +      P  +H  +      
Sbjct: 1950 PVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHV 2009

Query: 123  KPYPHILSTPAAQTM----------SAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDL 172
             P+   L TP+  T+          SA    T    +  P   T    TG  ++ P    
Sbjct: 2010 PPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPP---TTLKATGSTHTAP---- 2062

Query: 173  GVMLPAIKTESGLSQTQSPLQSGCLSYS--------PGFSTPQPGQTPYSYQMPGSSFAP 224
                P   T SG SQT S   +   S S        P  S+ +P  +P + Q+P  S A 
Sbjct: 2063 ----PMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSAT 2118

Query: 225  ---SSTIYANNSVSNSTNFSGSQQDY-PSYTAFGQNQYAQYYSASTY-GAYMTSNNTADG 279
               S+T   ++S S S +   +   Y PS  +  Q       ++S++  A + S   + G
Sbjct: 2119 TPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSG 2178

Query: 280  TPSSTSTYQLQESL 293
            + SS ST+    S+
Sbjct: 2179 SHSSLSTHPTTASV 2192


>gi|24430146 nucleoporin 153kDa [Homo sapiens]
          Length = 1475

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 81/348 (23%), Positives = 125/348 (35%), Gaps = 44/348 (12%)

Query: 8    NEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT----------PGSSKLEKSN 57
            +EQ+  +  ++S  S S    S +  +  +  T   G  T          P  S L  S+
Sbjct: 1138 SEQTKDENSSKSTFSFSMTKPSEKESEQPAKATFAFGAQTSTTADQGAAKPVFSFLNNSS 1197

Query: 58   LSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP 117
             SS++  T+  G  +    T   N    T   G  +      + ++SS +   +    S 
Sbjct: 1198 SSSSTPATSAGG-GIFGSSTSSSNPPVATFVFGQSS------NPVSSSAFGNTAESSTSQ 1250

Query: 118  QLYPSKPYPHILS-------TPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTY 170
             L  S+      +       TP      A +  T  SG    A  T+ S  G  +   T 
Sbjct: 1251 SLLFSQDSKLATTSSTGTAVTPFVFGPGASSNNTTTSGFGFGATTTS-SSAGSSFVFGT- 1308

Query: 171  DLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQP---GQTPYSYQMPGSSFAPSST 227
              G   P+     G +QT +         S G S P P   G    S  +  +   P+  
Sbjct: 1309 --GPSAPSASPAFGANQTPT------FGQSQGASQPNPPGFGSISSSTALFPTGSQPAPP 1360

Query: 228  IYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTY 287
             +   S S+     G Q   PS +AFG        SA  +G+  T+ N  + +PS   T+
Sbjct: 1361 TFGTVSSSSQPPVFGQQ---PSQSAFGSGTTPNSSSAFQFGSSTTNFNFTNNSPSGVFTF 1417

Query: 288  QLQESLPGLTNQP---GEFDTMQSPST-PIKDLDERTCRSSGSKSRGR 331
                S P  + QP   G F   QSP+   +    +    SSG+   GR
Sbjct: 1418 GANSSTPAASAQPSGSGGFPFNQSPAAFTVGSNGKNVFSSSGTSFSGR 1465


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 88/342 (25%), Positives = 131/342 (38%), Gaps = 51/342 (14%)

Query: 9   EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
           E +   + T   +S + ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 15  ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 74

Query: 62  SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQL 119
           S    GT V      T  L    TT+    G+++T    GS  T+ G S +S   +S   
Sbjct: 75  SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST-TTPGLSEKSTTFHS--- 130

Query: 120 YPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY--SQTGQP---------YSLP 168
             S   P    +PA+ T S  + ++  S  +  + +T      T  P         +S P
Sbjct: 131 --SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 188

Query: 169 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTP--QPGQTPYSYQMPGSSFAPSS 226
                 +LPA  T SG SQ  +   S     SPG +     PG T         SF   S
Sbjct: 189 GSTDTTLLPASTTTSGPSQESTTSHS-----SPGSTDTALSPGST------TALSFGQES 237

Query: 227 TIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 286
           T + ++  S  T        +P  T       A     S+ G+  T+ + A    SSTS 
Sbjct: 238 TTFHSSPGSTHTTL------FPDSTTSSGIVEASTRVHSSTGSPRTTLSPA----SSTSP 287

Query: 287 YQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTC--RSSGS 326
               ES    T+      T   PST    ++E T   RS GS
Sbjct: 288 GLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 329



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 66/279 (23%), Positives = 108/279 (38%), Gaps = 47/279 (16%)

Query: 37  SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
           SP T +    +       +S    T   +  T  S  +  T P+  S T   +      T
Sbjct: 274 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 333

Query: 97  FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 156
              +  T+SG+S +S   +S         P    T  +   S  +G ++ S        T
Sbjct: 334 HFPASSTTSGHSEKSTIFHSS--------PDASGTTPSSAHSTTSGVSEESS-------T 378

Query: 157 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGF-STPQPGQTPYSY 215
           ++SQ G  ++          P   T SGLSQ  +   S   S      +TP P       
Sbjct: 379 SHSQPGSTHT-------TAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSP------- 424

Query: 216 QMPGSSFAP---SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMT 272
             PG++ AP   S+T ++  S + +T+FS S       T  G+++     S + + +  +
Sbjct: 425 --PGTTAAPVEVSTTYHSRPSSTPTTHFSASS------TTLGRSEE----STTVHSSPGS 472

Query: 273 SNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
           +  TA   P ST+T  L E      + P   DT  SP++
Sbjct: 473 TETTA--LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 509


>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
           sapiens]
          Length = 600

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 73/276 (26%), Positives = 102/276 (36%), Gaps = 43/276 (15%)

Query: 104 SSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGM--QQPAVYTAYSQT 161
           + GY+ ++   Y  Q Y +   P  +S   AQT + Y GQT Y+    Q P  YT  +  
Sbjct: 26  TQGYA-QTTQAYGQQSYGTYGQPTDVSYTQAQTTATY-GQTAYATSYGQPPTGYTTPTAP 83

Query: 162 GQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSS 221
            Q YS P    G    A  T +    T     +   +Y    + P  GQ P +   P S 
Sbjct: 84  -QAYSQPVQGYGT--GAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQP-AATAPTSY 139

Query: 222 FAPSSTIYANNSVSNSTNFS-----GSQQDYPSYTAFGQNQYAQY------YS------A 264
            +   T Y  +S S    +      G Q  Y   +++GQ     Y      YS      +
Sbjct: 140 SSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYS 199

Query: 265 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLD--ERTCR 322
               +Y   ++     PSS   Y  QES  G  + PGE  +M  P    +     +R   
Sbjct: 200 QQSSSYGQQSSFRQDHPSSMGVYG-QES--GGFSGPGENRSMSGPDNRGRGRGGFDRGGM 256

Query: 323 SSGSKSRGRGRK---------NNPSPP----PDSDL 345
           S G +  GRG           N P  P    PD DL
Sbjct: 257 SRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDL 292



 Score = 38.9 bits (89), Expect = 0.014
 Identities = 48/173 (27%), Positives = 67/173 (38%), Gaps = 29/173 (16%)

Query: 77  TEPLNSSETTATTGDGALDTFTGSVITS-SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQ 135
           T P   S+     G GA DT T +V T+ + Y+ +SA+   P       YP     PAA 
Sbjct: 81  TAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQP------AYPAYGQQPAAT 134

Query: 136 TMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSG 195
             ++Y+  TQ +   Q + Y+  +  GQP S               +S   Q  S  Q  
Sbjct: 135 APTSYS-STQPTSYDQSS-YSQQNTYGQPSS------------YGQQSSYGQQSSYGQQP 180

Query: 196 CLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVS------NSTNFSG 242
             SY P   T    Q P  Y    SS+   S+   ++  S       S  FSG
Sbjct: 181 PTSYPP--QTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSG 231


>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
           sapiens]
          Length = 655

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 78/296 (26%), Positives = 109/296 (36%), Gaps = 56/296 (18%)

Query: 77  TEPLNSSETTATTGDGALDTFTGSVITS-SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQ 135
           T P   S+     G GA DT T +V T+ + Y+ +SA+   P       YP     PAA 
Sbjct: 81  TAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQP------AYPAYGQQPAAT 134

Query: 136 TMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSG 195
             +      + +   QP      S TG  Y+ P+   G        +S  S  Q P   G
Sbjct: 135 APTRPQDGNKPTETSQP-----QSSTG-GYNQPSLGYG--------QSNYSYPQVP---G 177

Query: 196 CLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQ 255
                P  + P    T YS   P +S+  SS  Y+  +     +  G Q  Y   +++GQ
Sbjct: 178 SYPMQPVTAPPSYPPTSYSSTQP-TSYDQSS--YSQQNTYGQPSSYGQQSSYGQQSSYGQ 234

Query: 256 NQYAQY------YS------ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEF 303
                Y      YS      +    +Y   ++     PSS   Y  QES  G  + PGE 
Sbjct: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG-QES--GGFSGPGEN 291

Query: 304 DTMQSPSTPIKDLD--ERTCRSSGSKSRGRGRK--------NNPSPP----PDSDL 345
            +M  P    +     +R   S G +  GRG          N P  P    PD DL
Sbjct: 292 RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGGPMDEGPDLDL 347



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 72/287 (25%), Positives = 97/287 (33%), Gaps = 65/287 (22%)

Query: 104 SSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGM--QQPAVYTAYSQT 161
           + GY+ ++   Y  Q Y +   P  +S   AQT + Y GQT Y+    Q P  YT  +  
Sbjct: 26  TQGYA-QTTQAYGQQSYGTYGQPTDVSYTQAQTTATY-GQTAYATSYGQPPTGYTTPTAP 83

Query: 162 GQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGF------------------ 203
            Q YS P    G       T +  +   S          P +                  
Sbjct: 84  -QAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDG 142

Query: 204 ----STPQP--------------GQTPYSY-QMPGS-----SFAPSSTIYANNSVSNSTN 239
                T QP              GQ+ YSY Q+PGS       AP S  Y   S S++  
Sbjct: 143 NKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS--YPPTSYSSTQP 200

Query: 240 FSGSQQDYPSYTAFGQ----NQYAQYYSASTYG-----AYMTSNNTADGTPS----STST 286
            S  Q  Y     +GQ     Q + Y   S+YG     +Y     +    PS     +S+
Sbjct: 201 TSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSS 260

Query: 287 YQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGR 333
           Y  Q S     + P         S       E     SG  +RGRGR
Sbjct: 261 YGQQSSF--RQDHPSSMGVYGQESGGFSGPGENR-SMSGPDNRGRGR 304


>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
           sapiens]
          Length = 656

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 78/297 (26%), Positives = 109/297 (36%), Gaps = 57/297 (19%)

Query: 77  TEPLNSSETTATTGDGALDTFTGSVITS-SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQ 135
           T P   S+     G GA DT T +V T+ + Y+ +SA+   P       YP     PAA 
Sbjct: 81  TAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQP------AYPAYGQQPAAT 134

Query: 136 TMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSG 195
             +      + +   QP      S TG  Y+ P+   G        +S  S  Q P   G
Sbjct: 135 APTRPQDGNKPTETSQP-----QSSTG-GYNQPSLGYG--------QSNYSYPQVP---G 177

Query: 196 CLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQ 255
                P  + P    T YS   P +S+  SS  Y+  +     +  G Q  Y   +++GQ
Sbjct: 178 SYPMQPVTAPPSYPPTSYSSTQP-TSYDQSS--YSQQNTYGQPSSYGQQSSYGQQSSYGQ 234

Query: 256 NQYAQY------YS------ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEF 303
                Y      YS      +    +Y   ++     PSS   Y  QES  G  + PGE 
Sbjct: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG-QES--GGFSGPGEN 291

Query: 304 DTMQSPSTPIKDLD--ERTCRSSGSKSRGRGRK---------NNPSPP----PDSDL 345
            +M  P    +     +R   S G +  GRG           N P  P    PD DL
Sbjct: 292 RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDL 348



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 72/287 (25%), Positives = 97/287 (33%), Gaps = 65/287 (22%)

Query: 104 SSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGM--QQPAVYTAYSQT 161
           + GY+ ++   Y  Q Y +   P  +S   AQT + Y GQT Y+    Q P  YT  +  
Sbjct: 26  TQGYA-QTTQAYGQQSYGTYGQPTDVSYTQAQTTATY-GQTAYATSYGQPPTGYTTPTAP 83

Query: 162 GQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGF------------------ 203
            Q YS P    G       T +  +   S          P +                  
Sbjct: 84  -QAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDG 142

Query: 204 ----STPQP--------------GQTPYSY-QMPGS-----SFAPSSTIYANNSVSNSTN 239
                T QP              GQ+ YSY Q+PGS       AP S  Y   S S++  
Sbjct: 143 NKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS--YPPTSYSSTQP 200

Query: 240 FSGSQQDYPSYTAFGQ----NQYAQYYSASTYG-----AYMTSNNTADGTPS----STST 286
            S  Q  Y     +GQ     Q + Y   S+YG     +Y     +    PS     +S+
Sbjct: 201 TSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSS 260

Query: 287 YQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGR 333
           Y  Q S     + P         S       E     SG  +RGRGR
Sbjct: 261 YGQQSSF--RQDHPSSMGVYGQESGGFSGPGENR-SMSGPDNRGRGR 304


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 72/285 (25%), Positives = 110/285 (38%), Gaps = 38/285 (13%)

Query: 48  PGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALD-TFTGSVITSSG 106
           P +S +  +++ +T++  + T        T  L+   TT  +   + D T + +  TSSG
Sbjct: 173 PKTSPITSASMETTALPGSTT--------TAGLSEKSTTFYSSPRSPDRTLSPARTTSSG 224

Query: 107 YSPRSAHQYSPQLYPSKPYP-HILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQ-TGQP 164
            S +S   +S      +P P H ++ P + TM   + ++  S     +  T  S  T  P
Sbjct: 225 VSEKSTTSHS------RPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTP 278

Query: 165 YSL----------PTYDLGVMLPAIKTESGLSQTQSPLQSGC----LSYSPGFSTPQPGQ 210
            SL          P Y     LP   T SGL +  +P+ S       + SP  ST   G+
Sbjct: 279 SSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGE 338

Query: 211 TPYSYQMPGS---SFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTY 267
                  P S   S APS T  A   V  ST +  S    P+ T F  +     +S  + 
Sbjct: 339 PTTFQSWPSSKDTSPAPSGTTSA--FVKLSTTYHSSPSSTPT-THFSASSTTLGHSEEST 395

Query: 268 GAYMTSNNTADGTPSSTS-TYQLQESLPGLTNQPGEFDTMQSPST 311
             + +   TA   P + S T    E        PG   TM  P +
Sbjct: 396 PVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPES 440



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 78/377 (20%), Positives = 126/377 (33%), Gaps = 67/377 (17%)

Query: 9    EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
            E     + T   +S   ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 1246 ESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHS 1305

Query: 62   SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYP 121
            S  TNG         T    +  TT     G+++T   S  T+ G S +S   YS    P
Sbjct: 1306 SPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSP 1365

Query: 122  SKPYPHILSTPAAQTMSAYAGQ-------------------TQYSGMQQPAVYTAYSQTG 162
             +       +PA+ T S+ +G+                   T  SG+ Q +  T +S+ G
Sbjct: 1366 DQTL-----SPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQEST-TFHSKPG 1419

Query: 163  Q---------------------PYSLPTYDLGVMLPAIKTESGLSQTQSPLQSG------ 195
                                  P+S P   L  + PA  T  GLS+  +   S       
Sbjct: 1420 STETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTET 1479

Query: 196  -CLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 254
               S+S   S      TP+    PG +            +   +    S  D    T   
Sbjct: 1480 TAFSHSNTMSIHSQQSTPFP-DSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLP 1538

Query: 255  QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIK 314
                A          Y++       +P+ T+ +    S  GLT +   F T  S ++ I 
Sbjct: 1539 ARSTASDLVGEPTTFYISP------SPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIV 1592

Query: 315  DLDERTCRSSGSKSRGR 331
              +     + G    G+
Sbjct: 1593 STESLETLAPGLCQEGQ 1609



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 76/336 (22%), Positives = 119/336 (35%), Gaps = 38/336 (11%)

Query: 19   SDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTE 78
            S+ S + +SR       A P +      TPG S+   ++ SS   T       L A  T 
Sbjct: 912  SEESTTSHSRPGSTHTTAFPDSTT----TPGLSRHSTTSHSSPGSTDT---TLLPASTTT 964

Query: 79   PLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQT 136
             L    TT+    G+ +T    GS  T++G S +S   YS     S   P    +PA+ T
Sbjct: 965  XLVGEPTTSPISSGSTETTALPGST-TTAGLSEKSTTFYS-----SPRSPDTTLSPASTT 1018

Query: 137  MSAYAGQTQYSGMQQPAVYTAY-----------SQTGQPYSLPTYDLGVMLPAIKTESGL 185
             S  + ++  S  +  + +T              ++   +S P      + P   T S L
Sbjct: 1019 SSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSL 1078

Query: 186  SQTQSPLQSGCLSYSPGFS--TPQPGQTPYSYQMPGSSFAPSSTIYANNSVS--NSTNFS 241
                +   SG     PG +  T  P  T  S  +  S+   SST     ++S   ST   
Sbjct: 1079 GPESTTFHSG-----PGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQ 1133

Query: 242  GSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPG 301
            G    + S+ +      A     +T  A++  + T+ G+PSS  T     S         
Sbjct: 1134 GESTTFQSWPSSKDTMPAP---PTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEE 1190

Query: 302  EFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 337
                  SP  P          +SG         ++P
Sbjct: 1191 STTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSP 1226



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 71/309 (22%), Positives = 107/309 (34%), Gaps = 47/309 (15%)

Query: 37   SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
            S HT    G T      ++S  S +S  +  T +S  +     L    TT  +G G+ +T
Sbjct: 1035 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPRSTTASSLGPESTTFHSGPGSTET 1094

Query: 97   FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS------GMQ 150
                 +     +     + S  ++ S   P    +PA  T       T  S       M 
Sbjct: 1095 ----TLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMP 1150

Query: 151  QPAVYT------AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS 204
             P   T      + +  G P S+PT        A  T  G S+  + + S         S
Sbjct: 1151 APPTTTSAFVELSTTSHGSPSSIPT----THFSASSTTFGRSEESTTVHS---------S 1197

Query: 205  TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP-SYTAFGQNQYAQYYS 263
               P  TP   +   S     ST Y ++  S  T        +P S TA G+++ ++   
Sbjct: 1198 PVAPATTPSPARSTTSGLVEESTAYHSSPGSTQT------MHFPESSTASGRSEESRTSH 1251

Query: 264  ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSP--STPIKDLDERTC 321
            +ST        +T    PS+TS   L E      + PG   T   P  ST     +E T 
Sbjct: 1252 SST-------THTISSPPSTTSA--LVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTA 1302

Query: 322  RSSGSKSRG 330
              S   + G
Sbjct: 1303 SHSSPDTNG 1311



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 63/280 (22%), Positives = 110/280 (39%), Gaps = 68/280 (24%)

Query: 77   TEPLNSSETTATTGDGALDTFTGSVIT---SSGYSPRSAHQYSPQLYPSKPYPHILSTPA 133
            T+ ++  E+  T+G G   T + S  T   SS  S  SA    P  Y S        +P 
Sbjct: 760  TQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHS--------SPG 811

Query: 134  AQTMSAYAGQTQYSGMQQPAVYTAYSQ--TGQPYSLPTYDLGVMLPAIKTESGL--SQTQ 189
            +   + +   +  SG  + ++ +  SQ  TG           ++LPA  T S L    T 
Sbjct: 812  STATTHFPDSSTTSGRSEESIASHSSQDATGT----------IVLPARSTNSVLLGESTT 861

Query: 190  SPLQSGCLSYS--PGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDY 247
            SP+ SG +  +  PG ST  PG +  S     S  +P++T+    S +++T+   S++  
Sbjct: 862  SPISSGSMETTALPG-STTTPGLSERSTTFHSSPRSPATTL----SPASTTSSGVSEEST 916

Query: 248  PSYTAFGQNQYAQYYSAST---YGAYMTSNNTADGT------------------------ 280
             S++  G      +  ++T      + T+++++ G+                        
Sbjct: 917  TSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPIS 976

Query: 281  ---------PSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
                     P ST+T  L E      + P   DT  SP++
Sbjct: 977  SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 1016



 Score = 33.1 bits (74), Expect = 0.77
 Identities = 57/261 (21%), Positives = 91/261 (34%), Gaps = 19/261 (7%)

Query: 60   STSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQL 119
            S S TT G       V + P+      ATT   A  T +G V  S+ Y        SP  
Sbjct: 1179 SASSTTFGRSEESTTVHSSPV----APATTPSPARSTTSGLVEESTAYHS------SPGS 1228

Query: 120  YPSKPYPHILSTPAAQTMSAYA-GQTQYSGMQQPAVYTAYSQTGQPY-SLPTYDLGVMLP 177
              +  +P   +       S  +   T ++    P+  +A  +    Y S P        P
Sbjct: 1229 TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFP 1288

Query: 178  AIKTESGLSQTQ-----SPLQSGCLSYSPGFSTP-QPGQTPYSYQMPGSSFAPSSTIYAN 231
               T SG S+       SP  +G       F+T  +  ++   Y  PGS     ++    
Sbjct: 1289 ESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATT 1348

Query: 232  NSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-ADGTPSSTSTYQLQ 290
              +S  +    S    P  T    +  +   S      Y  + +T     P+ST+T  L 
Sbjct: 1349 PGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLS 1408

Query: 291  ESLPGLTNQPGEFDTMQSPST 311
            +      ++PG  +T  SP +
Sbjct: 1409 QESTTFHSKPGSTETTLSPGS 1429


>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
          Length = 978

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 78/377 (20%), Positives = 126/377 (33%), Gaps = 67/377 (17%)

Query: 9   EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
           E     + T   +S   ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 275 ESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHS 334

Query: 62  SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYP 121
           S  TNG         T    +  TT     G+++T   S  T+ G S +S   YS    P
Sbjct: 335 SPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTTTTPGLSAKSTILYSSSRSP 394

Query: 122 SKPYPHILSTPAAQTMSAYAGQ-------------------TQYSGMQQPAVYTAYSQTG 162
            +       +PA+ T S+ +G+                   T  SG+ Q +  T +S+ G
Sbjct: 395 DQTL-----SPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQEST-TFHSKPG 448

Query: 163 Q---------------------PYSLPTYDLGVMLPAIKTESGLSQTQSPLQSG------ 195
                                 P+S P   L  + PA  T  GLS+  +   S       
Sbjct: 449 STETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTET 508

Query: 196 -CLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 254
              S+S   S      TP+    PG +            +   +    S  D    T   
Sbjct: 509 TAFSHSNTMSIHSQQSTPFP-DSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLP 567

Query: 255 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIK 314
               A          Y++       +P+ T+ +    S  GLT +   F T  S ++ I 
Sbjct: 568 ARSTASDLVGEPTTFYISP------SPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIV 621

Query: 315 DLDERTCRSSGSKSRGR 331
             +     + G    G+
Sbjct: 622 STESLETLAPGLCQEGQ 638



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 63/298 (21%), Positives = 107/298 (35%), Gaps = 40/298 (13%)

Query: 37  SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
           S HT    G T      ++S  S +S  +  T +S  +     L    TT  +G G+ +T
Sbjct: 64  STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTET 123

Query: 97  FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQ----- 151
                +     +     + S  ++ S   PH   +PA  T       T  S         
Sbjct: 124 ----TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 179

Query: 152 --PAVYTAY-----SQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS 204
             P   +A+     +  G P S PT        A  T  G S+  + + S  ++ +   +
Sbjct: 180 APPTTTSAFVELSTTSHGSPSSTPT----THFSASSTTLGRSEESTTVHSSPVATA---T 232

Query: 205 TPQPGQTPYS---------YQMPGSS----FAPSSTIYANNSVSNSTNFSGSQ--QDYPS 249
           TP P ++  S         +  PGS+    F  SST    +  S +++ S +      PS
Sbjct: 233 TPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPS 292

Query: 250 YTAFGQNQYAQYYSA--STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDT 305
            T+    +   Y+S+  S    +   ++T  G    ++         G+T  P  F T
Sbjct: 293 TTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTT 350



 Score = 35.8 bits (81), Expect = 0.12
 Identities = 60/272 (22%), Positives = 95/272 (34%), Gaps = 19/272 (6%)

Query: 49  GSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYS 108
           GS     +   S S TT G       V + P+     TATT   A  T +G V  S+ Y 
Sbjct: 197 GSPSSTPTTHFSASSTTLGRSEESTTVHSSPV----ATATTPSPARSTTSGLVEESTAYH 252

Query: 109 PRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYA-GQTQYSGMQQPAVYTAYSQTGQPY-S 166
                  SP    +  +P   +       S  +   T ++    P+  +A  +    Y S
Sbjct: 253 S------SPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHS 306

Query: 167 LPTYDLGVMLPAIKTESGLSQTQ-----SPLQSGCLSYSPGFSTP-QPGQTPYSYQMPGS 220
            P        P   T SG S+       SP  +G       F+T  +  ++   Y  PGS
Sbjct: 307 SPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGS 366

Query: 221 SFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-ADG 279
                ++      +S  +    S    P  T    +  +   S      Y  + +T    
Sbjct: 367 METTLASTTTTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTA 426

Query: 280 TPSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
            P+ST+T  L +      ++PG  +T  SP +
Sbjct: 427 FPASTTTSGLSQESTTFHSKPGSTETTLSPGS 458


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 72/285 (25%), Positives = 110/285 (38%), Gaps = 38/285 (13%)

Query: 48  PGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALD-TFTGSVITSSG 106
           P +S +  +++ +T++  + T        T  L+   TT  +   + D T + +  TSSG
Sbjct: 108 PKTSPITSASMETTALPGSTT--------TAGLSEKSTTFYSSPRSPDRTLSPARTTSSG 159

Query: 107 YSPRSAHQYSPQLYPSKPYP-HILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQ-TGQP 164
            S +S   +S      +P P H ++ P + TM   + ++  S     +  T  S  T  P
Sbjct: 160 VSEKSTTSHS------RPGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTP 213

Query: 165 YSL----------PTYDLGVMLPAIKTESGLSQTQSPLQSGC----LSYSPGFSTPQPGQ 210
            SL          P Y     LP   T SGL +  +P+ S       + SP  ST   G+
Sbjct: 214 SSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGE 273

Query: 211 TPYSYQMPGS---SFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTY 267
                  P S   S APS T  A   V  ST +  S    P+ T F  +     +S  + 
Sbjct: 274 PTTFQSWPSSKDTSPAPSGTTSA--FVKLSTTYHSSPSSTPT-THFSASSTTLGHSEEST 330

Query: 268 GAYMTSNNTADGTPSSTS-TYQLQESLPGLTNQPGEFDTMQSPST 311
             + +   TA   P + S T    E        PG   TM  P +
Sbjct: 331 PVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPES 375



 Score = 30.4 bits (67), Expect = 5.0
 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 15/148 (10%)

Query: 9   EQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDT---PGSS----KLEKSNLSST 61
           E +   + T   +S + ++ S  +++  S H+  G   T   P SS    + E+S  S +
Sbjct: 712 ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHS 771

Query: 62  SVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT--FTGSVITSSGYSPRSAHQYSPQL 119
           S    GT V         L    TT+    G+++T    GS  T+ G S RS   +S   
Sbjct: 772 SQDATGTIVLPARSTNSVLLGESTTSPISSGSMETTALPGST-TTPGLSERSTTFHS--- 827

Query: 120 YPSKPYPHILSTPAAQTMSAYAGQTQYS 147
             S   P    +PA+ T S  + ++  S
Sbjct: 828 --SPRSPATTLSPASTTSSGVSEESTTS 853


>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
           sapiens]
          Length = 354

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 71/271 (26%), Positives = 102/271 (37%), Gaps = 44/271 (16%)

Query: 77  TEPLNSSETTATTGDGALDTFTGSVITS-SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQ 135
           T P   S+     G GA DT T +V T+ + Y+ +SA+   P       YP     PAA 
Sbjct: 81  TAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQP------AYPAYGQQPAAT 134

Query: 136 TMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSG 195
             +      + +   QP      S TG  Y+ P+   G        +S  S  Q P   G
Sbjct: 135 APTRPQDGNKPTETSQP-----QSSTG-GYNQPSLGYG--------QSNYSYPQVP---G 177

Query: 196 CLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQ 255
                P  + P    T YS   P +S+  SS  Y+  +     +  G Q  Y   +++GQ
Sbjct: 178 SYPMQPVTAPPSYPPTSYSSTQP-TSYDQSS--YSQQNTYGQPSSYGQQSSYGQQSSYGQ 234

Query: 256 NQYAQY------YS------ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEF 303
                Y      YS      +    +Y   ++     PSS   Y  QES  G  + PGE 
Sbjct: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG-QES--GGFSGPGEN 291

Query: 304 DTMQSPSTPIKDLD--ERTCRSSGSKSRGRG 332
            +M  P    +     +R   S G +  GRG
Sbjct: 292 RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG 322



 Score = 37.0 bits (84), Expect = 0.054
 Identities = 72/287 (25%), Positives = 97/287 (33%), Gaps = 65/287 (22%)

Query: 104 SSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGM--QQPAVYTAYSQT 161
           + GY+ ++   Y  Q Y +   P  +S   AQT + Y GQT Y+    Q P  YT  +  
Sbjct: 26  TQGYA-QTTQAYGQQSYGTYGQPTDVSYTQAQTTATY-GQTAYATSYGQPPTGYTTPTAP 83

Query: 162 GQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGF------------------ 203
            Q YS P    G       T +  +   S          P +                  
Sbjct: 84  -QAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDG 142

Query: 204 ----STPQP--------------GQTPYSY-QMPGS-----SFAPSSTIYANNSVSNSTN 239
                T QP              GQ+ YSY Q+PGS       AP S  Y   S S++  
Sbjct: 143 NKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS--YPPTSYSSTQP 200

Query: 240 FSGSQQDYPSYTAFGQ----NQYAQYYSASTYG-----AYMTSNNTADGTPS----STST 286
            S  Q  Y     +GQ     Q + Y   S+YG     +Y     +    PS     +S+
Sbjct: 201 TSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSS 260

Query: 287 YQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGR 333
           Y  Q S     + P         S       E     SG  +RGRGR
Sbjct: 261 YGQQSSF--RQDHPSSMGVYGQESGGFSGPGENR-SMSGPDNRGRGR 304


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 70/250 (28%), Positives = 97/250 (38%), Gaps = 38/250 (15%)

Query: 105 SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQ- 163
           SGY  +    Y  Q     P+P     P +Q   +     Q S  QQP       Q+ Q 
Sbjct: 460 SGYGQQGQTPYYNQ---QSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516

Query: 164 PYS-LPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSF 222
           PYS  P+       PA    S  S TQ   QS      P +S PQ  Q+PY  Q P    
Sbjct: 517 PYSQQPSQPPHQQSPA-PYPSQQSTTQQHPQS-----QPPYSQPQ-AQSPYQQQQPQQP- 568

Query: 223 APSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQY--AQYYSASTYGAYMTSNNTADGT 280
           APS       ++S    +   Q      TA+ Q ++   Q  S  ++G      + A   
Sbjct: 569 APS-------TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG------SQASSA 615

Query: 281 PSSTSTYQLQESLP-GLTNQPGEFDTMQSPSTPIKDLDERT--CRSSGSKSRG----RGR 333
           PS TS+   QE +   L ++P     +   S  I DL   T    S G  + G    +G 
Sbjct: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDL---SGSIDDLPMGTEGALSPGVSTSGISSSQGE 672

Query: 334 KNNPSPPPDS 343
           ++NP+  P S
Sbjct: 673 QSNPAQSPFS 682



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 59/257 (22%), Positives = 101/257 (39%), Gaps = 20/257 (7%)

Query: 23  QSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNS 82
           QSQ S+         P       D+ GS   + S+  S + +  G     L++++ P + 
Sbjct: 583 QSQQSQQTAYSQQRFPPPQELSQDSFGS---QASSAPSMTSSKGGQEDMNLSLQSRPSSL 639

Query: 83  SETTATTGDGALDTFTGSV---ITSSGYSPRSAHQYSPQLYPSKPY--PHI--LSTPAAQ 135
            + + +  D  + T  G++   +++SG S     Q +P   P  P+  PH+  +  P+  
Sbjct: 640 PDLSGSIDDLPMGT-EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPS 698

Query: 136 TMSAYAGQTQY-SGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 194
            + + A   Q  SG   PA         +P S  +    +M P++  +S ++Q +  +Q 
Sbjct: 699 PVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDS--IMHPSMN-QSSIAQDRGYMQR 755

Query: 195 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSN---STNFSGSQQDYPSYT 251
                 P +S+PQPG      Q  G         Y  NS+ +        G Q  YP   
Sbjct: 756 N--PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQP 813

Query: 252 AFGQNQYAQYYSASTYG 268
            +     A Y SA   G
Sbjct: 814 NYNALPNANYPSAGMAG 830


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 70/250 (28%), Positives = 97/250 (38%), Gaps = 38/250 (15%)

Query: 105 SGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQ- 163
           SGY  +    Y  Q     P+P     P +Q   +     Q S  QQP       Q+ Q 
Sbjct: 460 SGYGQQGQTPYYNQ---QSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516

Query: 164 PYS-LPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSF 222
           PYS  P+       PA    S  S TQ   QS      P +S PQ  Q+PY  Q P    
Sbjct: 517 PYSQQPSQPPHQQSPA-PYPSQQSTTQQHPQS-----QPPYSQPQ-AQSPYQQQQPQQP- 568

Query: 223 APSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQY--AQYYSASTYGAYMTSNNTADGT 280
           APS       ++S    +   Q      TA+ Q ++   Q  S  ++G      + A   
Sbjct: 569 APS-------TLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSFG------SQASSA 615

Query: 281 PSSTSTYQLQESLP-GLTNQPGEFDTMQSPSTPIKDLDERT--CRSSGSKSRG----RGR 333
           PS TS+   QE +   L ++P     +   S  I DL   T    S G  + G    +G 
Sbjct: 616 PSMTSSKGGQEDMNLSLQSRPSSLPDL---SGSIDDLPMGTEGALSPGVSTSGISSSQGE 672

Query: 334 KNNPSPPPDS 343
           ++NP+  P S
Sbjct: 673 QSNPAQSPFS 682



 Score = 39.3 bits (90), Expect = 0.011
 Identities = 59/257 (22%), Positives = 101/257 (39%), Gaps = 20/257 (7%)

Query: 23  QSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNS 82
           QSQ S+         P       D+ GS   + S+  S + +  G     L++++ P + 
Sbjct: 583 QSQQSQQTAYSQQRFPPPQELSQDSFGS---QASSAPSMTSSKGGQEDMNLSLQSRPSSL 639

Query: 83  SETTATTGDGALDTFTGSV---ITSSGYSPRSAHQYSPQLYPSKPY--PHI--LSTPAAQ 135
            + + +  D  + T  G++   +++SG S     Q +P   P  P+  PH+  +  P+  
Sbjct: 640 PDLSGSIDDLPMGT-EGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPS 698

Query: 136 TMSAYAGQTQY-SGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 194
            + + A   Q  SG   PA         +P S  +    +M P++  +S ++Q +  +Q 
Sbjct: 699 PVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDS--IMHPSMN-QSSIAQDRGYMQR 755

Query: 195 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSN---STNFSGSQQDYPSYT 251
                 P +S+PQPG      Q  G         Y  NS+ +        G Q  YP   
Sbjct: 756 N--PQMPQYSSPQPGSALSPRQPSGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQP 813

Query: 252 AFGQNQYAQYYSASTYG 268
            +     A Y SA   G
Sbjct: 814 NYNALPNANYPSAGMAG 830


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 66/279 (23%), Positives = 108/279 (38%), Gaps = 47/279 (16%)

Query: 37  SPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGVSLLAVKTEPLNSSETTATTGDGALDT 96
           SP T +    +       +S    T   +  T  S  +  T P+  S T   +      T
Sbjct: 168 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTT 227

Query: 97  FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 156
              +  T+SG+S +S   +S         P    T  +   S  +G ++ S        T
Sbjct: 228 HFPASSTTSGHSEKSTIFHSS--------PDASGTTPSSAHSTTSGVSEESS-------T 272

Query: 157 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGF-STPQPGQTPYSY 215
           ++SQ G  ++          P   T SGLSQ  +   S   S      +TP P       
Sbjct: 273 SHSQPGSTHT-------TAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSP------- 318

Query: 216 QMPGSSFAP---SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMT 272
             PG++ AP   S+T ++  S + +T+FS S       T  G+++     S + + +  +
Sbjct: 319 --PGTTAAPVEVSTTYHSRPSSTPTTHFSASS------TTLGRSEE----STTVHSSPGS 366

Query: 273 SNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPST 311
           +  TA   P ST+T  L E      + P   DT  SP++
Sbjct: 367 TETTA--LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPAS 403



 Score = 30.8 bits (68), Expect = 3.8
 Identities = 38/178 (21%), Positives = 71/178 (39%), Gaps = 9/178 (5%)

Query: 165 YSLPTYDLGVMLPAIKTESGLSQ--TQSPLQSGCLSYSPGF--STPQPGQTPYSYQMPGS 220
           +S P      + PA  T SG+S+  T S  + G  +++  F  ST  PG + +S     S
Sbjct: 23  HSSPRSPATTLSPASTTSSGVSEESTTSHSRPGS-THTTAFPDSTTTPGLSRHSTTSHSS 81

Query: 221 SFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGT 280
             +  +T+      +++T    SQ+   S+++ G    A    ++T  ++   + T   +
Sbjct: 82  PGSTDTTLLP----ASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 137

Query: 281 PSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNPS 338
           P ST T    +S               S  +P   L   +  S G +      + +P+
Sbjct: 138 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPA 195


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,734,977
Number of Sequences: 37866
Number of extensions: 1201388
Number of successful extensions: 3963
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 191
Number of HSP's that attempted gapping in prelim test: 3451
Number of HSP's gapped (non-prelim): 542
length of query: 616
length of database: 18,247,518
effective HSP length: 108
effective length of query: 508
effective length of database: 14,157,990
effective search space: 7192258920
effective search space used: 7192258920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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