Guide to the Human Genome
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Search of human proteins with 98991760

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|98991760 eyes absent 4 isoform a [Homo sapiens]
         (639 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|98991760 eyes absent 4 isoform a [Homo sapiens]                   1286   0.0  
gi|26667257 eyes absent 4 isoform d [Homo sapiens]                   1268   0.0  
gi|98991763 eyes absent 4 isoform b [Homo sapiens]                   1224   0.0  
gi|19923100 eyes absent 1 isoform b [Homo sapiens]                    838   0.0  
gi|26667216 eyes absent 1 isoform b [Homo sapiens]                    838   0.0  
gi|26667222 eyes absent 1 isoform a [Homo sapiens]                    817   0.0  
gi|26667219 eyes absent 1 isoform c [Homo sapiens]                    763   0.0  
gi|26667227 eyes absent 2 isoform a [Homo sapiens]                    607   e-173
gi|26667240 eyes absent 2 isoform b [Homo sapiens]                    607   e-173
gi|26667235 eyes absent 2 isoform a [Homo sapiens]                    607   e-173
gi|26667232 eyes absent 2 isoform a [Homo sapiens]                    607   e-173
gi|26667230 eyes absent 2 isoform c [Homo sapiens]                    576   e-164
gi|26667243 eyes absent 3 [Homo sapiens]                              574   e-164
gi|151301154 mucin 6, gastric [Homo sapiens]                           58   3e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        55   3e-07
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    53   8e-07
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       50   8e-06
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s...    49   1e-05
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             49   1e-05
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    47   4e-05
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-05
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              46   9e-05
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            46   9e-05

>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
          Length = 639

 Score = 1286 bits (3329), Expect = 0.0
 Identities = 639/639 (100%), Positives = 639/639 (100%)

Query: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60
           MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS
Sbjct: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60

Query: 61  TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF 120
           TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF
Sbjct: 61  TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF 120

Query: 121 TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 180
           TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA
Sbjct: 121 TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 180

Query: 181 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 240
           YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM
Sbjct: 181 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 240

Query: 241 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 300
           PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA
Sbjct: 241 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 300

Query: 301 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 360
           DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP
Sbjct: 301 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 360

Query: 361 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 420
           SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH
Sbjct: 361 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 420

Query: 421 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 480
           LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK
Sbjct: 421 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 480

Query: 481 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 540
           LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS
Sbjct: 481 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 540

Query: 541 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV 600
           NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV
Sbjct: 541 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV 600

Query: 601 IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL
Sbjct: 601 IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639


>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
          Length = 639

 Score = 1268 bits (3280), Expect = 0.0
 Identities = 628/639 (98%), Positives = 632/639 (98%)

Query: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60
           MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS
Sbjct: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60

Query: 61  TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF 120
           TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF
Sbjct: 61  TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF 120

Query: 121 TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 180
           TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA
Sbjct: 121 TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 180

Query: 181 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 240
           YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM
Sbjct: 181 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 240

Query: 241 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 300
           PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA
Sbjct: 241 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 300

Query: 301 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 360
           DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP
Sbjct: 301 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 360

Query: 361 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 420
           SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH
Sbjct: 361 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 420

Query: 421 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 480
           LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK
Sbjct: 421 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 480

Query: 481 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 540
           LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS
Sbjct: 481 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 540

Query: 541 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV 600
           NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERI+ RFG  + YVV
Sbjct: 541 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIVSRFGTNITYVV 600

Query: 601 IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           IGDG +EE AA +HNMPFWRISSHSDLLALHQALELEYL
Sbjct: 601 IGDGRDEEHAANQHNMPFWRISSHSDLLALHQALELEYL 639


>gi|98991763 eyes absent 4 isoform b [Homo sapiens]
          Length = 616

 Score = 1224 bits (3168), Expect = 0.0
 Identities = 615/639 (96%), Positives = 616/639 (96%), Gaps = 23/639 (3%)

Query: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60
           MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS
Sbjct: 1   MEDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS 60

Query: 61  TSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTF 120
           TSVTTNGTG                       +SLLAVKTEPLNSSETTATTGDGALDTF
Sbjct: 61  TSVTTNGTG-----------------------VSLLAVKTEPLNSSETTATTGDGALDTF 97

Query: 121 TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 180
           TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA
Sbjct: 98  TGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTA 157

Query: 181 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 240
           YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM
Sbjct: 158 YSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQM 217

Query: 241 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 300
           PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA
Sbjct: 218 PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 277

Query: 301 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 360
           DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP
Sbjct: 278 DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNP 337

Query: 361 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 420
           SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH
Sbjct: 338 SPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTH 397

Query: 421 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 480
           LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK
Sbjct: 398 LFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRK 457

Query: 481 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 540
           LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS
Sbjct: 458 LAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRS 517

Query: 541 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV 600
           NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV
Sbjct: 518 NCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVV 577

Query: 601 IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL
Sbjct: 578 IGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 616


>gi|19923100 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score =  838 bits (2166), Expect = 0.0
 Identities = 436/623 (69%), Positives = 497/623 (79%), Gaps = 44/623 (7%)

Query: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTP 88
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT                    
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-------------------- 40

Query: 89  SSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-K 146
                    VKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +
Sbjct: 41  --------EVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNR 92

Query: 147 PYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTE 205
           PYPHIL TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE
Sbjct: 93  PYPHILPTPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTE 149

Query: 206 SGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFS 264
            GLSQ+QSP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+
Sbjct: 150 GGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFN 209

Query: 265 GSQQDYPSYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP 323
            SQQDYPSY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q 
Sbjct: 210 SSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQA 269

Query: 324 -----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDL 376
                 E+ T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDL
Sbjct: 270 VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDL 329

Query: 377 DETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 436
           DETIIVFHSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDD
Sbjct: 330 DETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 389

Query: 437 VSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYK 496
           VSSDDNGQDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYK
Sbjct: 390 VSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYK 449

Query: 497 NNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPAL 556
           NNVGGLLGPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPAL
Sbjct: 450 NNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPAL 509

Query: 557 AKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNM 616
           AKVLLY LG  FPIENIYSATKIGKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH M
Sbjct: 510 AKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAM 569

Query: 617 PFWRISSHSDLLALHQALELEYL 639
           PFWRISSHSDL+ALH ALELEYL
Sbjct: 570 PFWRISSHSDLMALHHALELEYL 592


>gi|26667216 eyes absent 1 isoform b [Homo sapiens]
          Length = 592

 Score =  838 bits (2166), Expect = 0.0
 Identities = 436/623 (69%), Positives = 497/623 (79%), Gaps = 44/623 (7%)

Query: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTP 88
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT                    
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-------------------- 40

Query: 89  SSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-K 146
                    VKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +
Sbjct: 41  --------EVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNR 92

Query: 147 PYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTE 205
           PYPHIL TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE
Sbjct: 93  PYPHILPTPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTE 149

Query: 206 SGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFS 264
            GLSQ+QSP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+
Sbjct: 150 GGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFN 209

Query: 265 GSQQDYPSYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP 323
            SQQDYPSY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q 
Sbjct: 210 SSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQA 269

Query: 324 -----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDL 376
                 E+ T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDL
Sbjct: 270 VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDL 329

Query: 377 DETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 436
           DETIIVFHSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDD
Sbjct: 330 DETIIVFHSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 389

Query: 437 VSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYK 496
           VSSDDNGQDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYK
Sbjct: 390 VSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYK 449

Query: 497 NNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPAL 556
           NNVGGLLGPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPAL
Sbjct: 450 NNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPAL 509

Query: 557 AKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNM 616
           AKVLLY LG  FPIENIYSATKIGKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH M
Sbjct: 510 AKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAM 569

Query: 617 PFWRISSHSDLLALHQALELEYL 639
           PFWRISSHSDL+ALH ALELEYL
Sbjct: 570 PFWRISSHSDLMALHHALELEYL 592


>gi|26667222 eyes absent 1 isoform a [Homo sapiens]
          Length = 559

 Score =  817 bits (2111), Expect = 0.0
 Identities = 416/556 (74%), Positives = 471/556 (84%), Gaps = 15/556 (2%)

Query: 96  LAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-KPYPHILS 153
           +AVKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +PYPHIL 
Sbjct: 7   VAVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNRPYPHILP 66

Query: 154 TPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQ 212
           TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y  G +   IKTE GLSQ+Q
Sbjct: 67  TPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY--GALWAGIKTEGGLSQSQ 123

Query: 213 SPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFSGSQQDYP 271
           SP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+ SQQDYP
Sbjct: 124 SPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFNSSQQDYP 183

Query: 272 SYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP-----GE 325
           SY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q       E
Sbjct: 184 SYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQAVTDPTAE 243

Query: 326 FDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDLDETIIVF 383
           + T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDLDETIIVF
Sbjct: 244 YSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDLDETIIVF 303

Query: 384 HSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 443
           HSLLTGSYA +YG+DPP +V+LGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG
Sbjct: 304 HSLLTGSYANRYGRDPPTSVSLGLRMEEMIFNLADTHLFFNDLEECDQVHIDDVSSDDNG 363

Query: 444 QDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYKNNVGGLL 503
           QDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYKNNVGGLL
Sbjct: 364 QDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYKNNVGGLL 423

Query: 504 GPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPALAKVLLYS 563
           GPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPALAKVLLY 
Sbjct: 424 GPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPALAKVLLYG 483

Query: 564 LGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNMPFWRISS 623
           LG  FPIENIYSATKIGKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH MPFWRISS
Sbjct: 484 LGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAMPFWRISS 543

Query: 624 HSDLLALHQALELEYL 639
           HSDL+ALH ALELEYL
Sbjct: 544 HSDLMALHHALELEYL 559


>gi|26667219 eyes absent 1 isoform c [Homo sapiens]
          Length = 557

 Score =  763 bits (1971), Expect = 0.0
 Identities = 408/623 (65%), Positives = 466/623 (74%), Gaps = 79/623 (12%)

Query: 30  MEMQDLASPHT-LVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTP 88
           MEMQDL SPH+ L G  ++P   KL  S+++S S+T NGT                    
Sbjct: 1   MEMQDLTSPHSRLSGSSESPSGPKLGNSHINSNSMTPNGT-------------------- 40

Query: 89  SSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSP-QLYPS-K 146
                    VKTEP++SSET +TT DG+L+ F+GS I SS +SPR  HQ+SP Q+YPS +
Sbjct: 41  --------EVKTEPMSSSETASTTADGSLNNFSGSAIGSSSFSPRPTHQFSPPQIYPSNR 92

Query: 147 PYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTE 205
           PYPHIL TP++QTM+AY GQTQ++ GMQQ   Y  Y Q GQPY + +Y        IKTE
Sbjct: 93  PYPHILPTPSSQTMAAY-GQTQFTTGMQQATAYATYPQPGQPYGISSY-------GIKTE 144

Query: 206 SGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA-NNSVSNSTNFS 264
            GLSQ+QSP Q+G LSY   FSTPQPGQ PYSYQM GSSF  SS IY  NNS++NS+ F+
Sbjct: 145 GGLSQSQSPGQTGFLSYGTSFSTPQPGQAPYSYQMQGSSFTTSSGIYTGNNSLTNSSGFN 204

Query: 265 GSQQDYPSYTAFGQNQYAQYYSASTYGA-YMTSNNTADGTPSSTSTYQLQESLPGLTNQP 323
            SQQDYPSY +FGQ QYAQYY++S Y A YMTS+NT+  TPS+ +TYQLQE   G+T+Q 
Sbjct: 205 SSQQDYPSYPSFGQGQYAQYYNSSPYPAHYMTSSNTSPTTPSTNATYQLQEPPSGITSQA 264

Query: 324 -----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRGRKNN-PSPPPDSDLERVFVWDL 376
                 E+ T+ SPSTPIKD D +R  R S  KSRGRGR+NN PSPPPDSDLERVF+WDL
Sbjct: 265 VTDPTAEYSTIHSPSTPIKDSDSDRLRRGSDGKSRGRGRRNNNPSPPPDSDLERVFIWDL 324

Query: 377 DETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFNDLEECDQVHIDD 436
           DETIIVFHSLLTGSYA +YG+                              ECDQVHIDD
Sbjct: 325 DETIIVFHSLLTGSYANRYGR------------------------------ECDQVHIDD 354

Query: 437 VSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFRYRRVKELYNTYK 496
           VSSDDNGQDLSTY+F TDGF AAA+SANLCL TGVRGGVDWMRKLAFRYRRVKE+YNTYK
Sbjct: 355 VSSDDNGQDLSTYNFGTDGFPAAATSANLCLATGVRGGVDWMRKLAFRYRRVKEIYNTYK 414

Query: 497 NNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCINVLVTTTQLIPAL 556
           NNVGGLLGPAKR+AWLQLRAEIE LTDSWLT ALK+LS+I +R+NC+N+LVTTTQLIPAL
Sbjct: 415 NNVGGLLGPAKREAWLQLRAEIEALTDSWLTLALKALSLIHSRTNCVNILVTTTQLIPAL 474

Query: 557 AKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDGVEEEQAAKKHNM 616
           AKVLLY LG  FPIENIYSATKIGKESCFERI+QRFGRKVVYVVIGDGVEEEQ AKKH M
Sbjct: 475 AKVLLYGLGIVFPIENIYSATKIGKESCFERIIQRFGRKVVYVVIGDGVEEEQGAKKHAM 534

Query: 617 PFWRISSHSDLLALHQALELEYL 639
           PFWRISSHSDL+ALH ALELEYL
Sbjct: 535 PFWRISSHSDLMALHHALELEYL 557


>gi|26667227 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97

Query: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144

Query: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203

Query: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263

Query: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323

Query: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383

Query: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443

Query: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 604
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503

Query: 605 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667240 eyes absent 2 isoform b [Homo sapiens]
          Length = 543

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 45  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 102

Query: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 103 SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 149

Query: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 150 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 208

Query: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 209 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 268

Query: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 269 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 328

Query: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 329 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 388

Query: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 389 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 448

Query: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 604
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 449 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 508

Query: 605 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 509 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 543


>gi|26667235 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97

Query: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144

Query: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203

Query: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263

Query: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323

Query: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383

Query: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443

Query: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 604
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503

Query: 605 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667232 eyes absent 2 isoform a [Homo sapiens]
          Length = 538

 Score =  607 bits (1564), Expect = e-173
 Identities = 318/515 (61%), Positives = 381/515 (73%), Gaps = 24/515 (4%)

Query: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97

Query: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251
           +Y       +IKTE  L+   SP QSG LSY   FST   GQ+PY+YQM G++       
Sbjct: 98  SY-------SIKTEDSLNH--SPGQSGFLSYGSSFSTSPTGQSPYTYQMHGTT----GFY 144

Query: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 145 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 203

Query: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 204 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 263

Query: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 264 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 323

Query: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 324 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 383

Query: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 384 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 443

Query: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 604
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 444 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 503

Query: 605 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 504 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 538


>gi|26667230 eyes absent 2 isoform c [Homo sapiens]
          Length = 514

 Score =  576 bits (1485), Expect = e-164
 Identities = 304/515 (59%), Positives = 365/515 (70%), Gaps = 48/515 (9%)

Query: 133 RSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYS-GMQQPAVYTAYSQTGQPYSLP 191
           +SA     QL+ S+  P +L    +  M+AY GQTQYS G+QQ   YTAY    Q Y +P
Sbjct: 40  KSAPLRVSQLF-SRSCPRVLPRQPSTAMAAY-GQTQYSAGIQQATPYTAYPPPAQAYGIP 97

Query: 192 TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTI 251
           +                                 FST   GQ+PY+YQM G++       
Sbjct: 98  S---------------------------------FSTSPTGQSPYTYQMHGTT----GFY 120

Query: 252 YANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQ 311
              N + N+  F    QDYPSY  F Q+QY QYY +S    Y+ +++    +P STSTY 
Sbjct: 121 QGGNGLGNAAGFGSVHQDYPSYPGFPQSQYPQYYGSSYNPPYVPASSICP-SPLSTSTYV 179

Query: 312 LQESLPGLTNQP-----GEFDTMQSPSTPIKDLD-ERTCRSSGSKSRGRG-RKNNPSPPP 364
           LQE+   + NQ      GE++T   PSTP K+ D +R  R+S  K RGR  R ++PSP  
Sbjct: 180 LQEASHNVPNQSSESLAGEYNTHNGPSTPAKEGDTDRPHRASDGKLRGRSKRSSDPSPAG 239

Query: 365 DSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEMIFNLADTHLFFN 424
           D+++ERVFVWDLDETII+FHSLLTG++A +YGKD   +V +GL MEEMIFNLADTHLFFN
Sbjct: 240 DNEIERVFVWDLDETIIIFHSLLTGTFASRYGKDTTTSVRIGLMMEEMIFNLADTHLFFN 299

Query: 425 DLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVRGGVDWMRKLAFR 484
           DLE+CDQ+H+DDVSSDDNGQDLSTY+F+ DGFH++A  ANLCL +GV GGVDWMRKLAFR
Sbjct: 300 DLEDCDQIHVDDVSSDDNGQDLSTYNFSADGFHSSAPGANLCLGSGVHGGVDWMRKLAFR 359

Query: 485 YRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKSLSIISTRSNCIN 544
           YRRVKE+YNTYKNNVGGL+G  KR+ WLQLRAE+E LTD WLT++LK+L++I++R NC+N
Sbjct: 360 YRRVKEMYNTYKNNVGGLIGTPKRETWLQLRAELEALTDLWLTHSLKALNLINSRPNCVN 419

Query: 545 VLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRFGRKVVYVVIGDG 604
           VLVTTTQLIPALAKVLLY LG  FPIENIYSATK GKESCFERIMQRFGRK VYVVIGDG
Sbjct: 420 VLVTTTQLIPALAKVLLYGLGSVFPIENIYSATKTGKESCFERIMQRFGRKAVYVVIGDG 479

Query: 605 VEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           VEEEQ AKKHNMPFWRIS H+DL AL  ALELEYL
Sbjct: 480 VEEEQGAKKHNMPFWRISCHADLEALRHALELEYL 514


>gi|26667243 eyes absent 3 [Homo sapiens]
          Length = 573

 Score =  574 bits (1480), Expect = e-164
 Identities = 298/527 (56%), Positives = 381/527 (72%), Gaps = 17/527 (3%)

Query: 124 VITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQ 183
           ++T + Y PRS++ Y+ Q+Y +KPY HILS P ++T  AY GQTQY  +QQ   Y  Y Q
Sbjct: 53  IMTCTDYIPRSSNDYTSQMYSAKPYAHILSVPVSET--AYPGQTQYQTLQQTQPYAVYPQ 110

Query: 184 TGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGS 243
             Q Y LP +  G + P +K ESGL QT SP Q   L+ + G +T QP    YSY +  S
Sbjct: 111 ATQTYGLPPF--GALWPGMKPESGLIQTPSPSQHSVLTCTTGLTTSQPSPAHYSYPIQAS 168

Query: 244 SFAPSSTIYANNSVSN---STNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTA 300
           S   +S I  +++++N   +   S S QDYP+YT  GQNQY   Y +S++G    +N+ A
Sbjct: 169 S-TNASLISTSSTIANIPAAAVASISNQDYPTYTILGQNQYQACYPSSSFGVTGQTNSDA 227

Query: 301 DGTPSSTSTYQLQES---LPGLTNQP-GEFDTMQSPS----TPIKDLDERTCRSSGSKSR 352
           + T  + +TYQ ++     P    Q     D   SPS    TP KD D+++ ++  SK+R
Sbjct: 228 ESTTLAATTYQSEKPSVMAPAPAAQRLSSGDPSTSPSLSQTTPSKDTDDQSRKNMTSKNR 287

Query: 353 GRGRKNNPSPPPDSDLERVFVWDLDETIIVFHSLLTGSYAQKYGKDPPMAVTLGLRMEEM 412
           G+ RK + +   DS+LERVF+WDLDETII+FHSLLTGSYAQKYGKDP + +  GL MEEM
Sbjct: 288 GK-RKADATSSQDSELERVFLWDLDETIIIFHSLLTGSYAQKYGKDPTVVIGSGLTMEEM 346

Query: 413 IFNLADTHLFFNDLEECDQVHIDDVSSDDNGQDLSTYSFATDGFHAAASSANLCLPTGVR 472
           IF +ADTHLFFNDLEECDQVH++DV+SDDNGQDLS YSF+TDGF  +  S +     GV+
Sbjct: 347 IFEVADTHLFFNDLEECDQVHVEDVASDDNGQDLSNYSFSTDGFSGSGGSGSHGSSVGVQ 406

Query: 473 GGVDWMRKLAFRYRRVKELYNTYKNNVGGLLGPAKRDAWLQLRAEIEGLTDSWLTNALKS 532
           GGVDWMRKLAFRYR+V+E+Y+ +K+NVGGLL P +++A  +LRAEIE LTDSWL  ALKS
Sbjct: 407 GGVDWMRKLAFRYRKVREIYDKHKSNVGGLLSPQRKEALQRLRAEIEVLTDSWLGTALKS 466

Query: 533 LSIISTRSNCINVLVTTTQLIPALAKVLLYSLGGAFPIENIYSATKIGKESCFERIMQRF 592
           L +I +R NC+NVL+TTTQL+PALAKVLLY LG  FPIENIYSATKIGKESCFERI+ RF
Sbjct: 467 LLLIQSRKNCVNVLITTTQLVPALAKVLLYGLGEIFPIENIYSATKIGKESCFERIVSRF 526

Query: 593 GRKVVYVVIGDGVEEEQAAKKHNMPFWRISSHSDLLALHQALELEYL 639
           G+KV YVVIGDG +EE AAK+HNMPFWRI++H DL++LHQALEL++L
Sbjct: 527 GKKVTYVVIGDGRDEEIAAKQHNMPFWRITNHGDLVSLHQALELDFL 573


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 79/331 (23%), Positives = 129/331 (38%), Gaps = 54/331 (16%)

Query: 15   TCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMT 74
            T T + ++ S +  SM    +  P TL   G T  +  +        ++TT+GT  + ++
Sbjct: 1633 TPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTM--------TLTTSGTS-QALS 1683

Query: 75   VLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRS 134
             LNTA    S ++ +S+T    A  T   N +    +TG   +   T    TS   S  S
Sbjct: 1684 SLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSG--TSQSRSSFS 1741

Query: 135  AHQYSPQLYP---SKPYPHILST----------------PAAQTMSAYAGQ--TQYSGMQ 173
              + S  L+    S  +P + ST                P A T SA + +  T ++   
Sbjct: 1742 TAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHS 1801

Query: 174  QPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQ--- 230
             P   T  S TG P +  ++      P        S   + L +   S+S    TP    
Sbjct: 1802 PPTGTTPISSTG-PVTATSFQTTTTYPTP------SHPHTTLPTHVPSFSTSLVTPSTHT 1854

Query: 231  ---PGQTPYS-----YQMPGSSFAPSSTIYANNSVSNSTNF----SGSQQDYPSYTAFGQ 278
               P  T  +     + MP  +  P +TI A  S   +       SG+ Q   S++    
Sbjct: 1855 VIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKT 1914

Query: 279  NQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
            +    Y+++ST+   +T  +T + TP  TST
Sbjct: 1915 STSLPYHTSSTHHPEVTPTSTTNITPKHTST 1945



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 71/310 (22%), Positives = 117/310 (37%), Gaps = 35/310 (11%)

Query: 38   PHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLA 97
            P T +     P S+ L   +  +  +TT+     + ++ +T    +   T   AT S   
Sbjct: 2001 PQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPPPTTLKATGSTHT 2060

Query: 98   VKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILS--TP 155
                 + +S T+ T    +  T + S I+SS + P+++    P    +   PH+ S  TP
Sbjct: 2061 APPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATTP 2120

Query: 156  ----------------AAQTMSAYAGQTQYSGM-QQPAVYTAYSQTGQPYSLPTYDLGVM 198
                            A  T+S+Y   +  S     P+V T+ S    P    T   G  
Sbjct: 2121 VSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSH 2180

Query: 199  LPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPG--SSFAPSSTIYANNS 256
                   +  S + SPL       SP  ST      P++   P   S+  P ST+    S
Sbjct: 2181 SSLSTHPTTASVSASPL----FPSSPAASTTIRATLPHTISSPFTLSALLPISTVTV--S 2234

Query: 257  VSNSTNFSGSQQDYPS--YTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTY-QLQ 313
             + S++ + S   +PS   T    +    + S ST     TS +T+  T   TS +  L 
Sbjct: 2235 PTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQST-----TSRSTSLTTRVPTSGFVSLT 2289

Query: 314  ESLPGLTNQP 323
              + G+   P
Sbjct: 2290 SGVTGIPTSP 2299



 Score = 38.9 bits (89), Expect = 0.015
 Identities = 65/300 (21%), Positives = 105/300 (35%), Gaps = 31/300 (10%)

Query: 38   PHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTV----------LNTADWLLSCNT 87
            P TL     T  S +  +    +T+VT   T G   T           +  A    + +T
Sbjct: 1256 PATLTSSKPTASSGEPPRP---TTAVTPQATSGLPPTATLRSTATKPTVTQATTRATAST 1312

Query: 88   PSSATMSLLAVKTEPLNSSETTATTGDG-ALDTFTGSVITSSGYSPRSAHQYSPQLY--P 144
             S AT S     T    +  T AT+G    L   T   +  +  +  +  + +P     P
Sbjct: 1313 ASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTPASTTGP 1372

Query: 145  SKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKT 204
            + P P   + P A   +     T+Y+  Q P    +    G P             A  T
Sbjct: 1373 TTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTT 1432

Query: 205  ESGLSQTQSPLQSGCLSYSPGFSTPQPGQ--TPYSYQM---------PGSSFAPSSTIYA 253
                S  ++ L +    +S    TP      TP   QM         P  +  P +T+ A
Sbjct: 1433 YPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKA 1492

Query: 254  NNSVSNSTNF----SGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
              S   +       SG+ Q + S++          +++ST+   +T  +T   TP+ TST
Sbjct: 1493 TGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTST 1552


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 84/334 (25%), Positives = 127/334 (38%), Gaps = 60/334 (17%)

Query: 40   TLVGGGDTPGSSKLEKS----------NLSSTSVTTNGTGGENMTVLNTADWLLSCNTPS 89
            TL G   TPG S+   +           LS  S+T+ G G E+ T  +      S  +P+
Sbjct: 2313 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2372

Query: 90   SATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYP 149
            S T   L+ ++  + SS   +T       T T SV    G  P + H             
Sbjct: 2373 STTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSV---RGEEPTTFH------------- 2416

Query: 150  HILSTPAAQTMSAYAGQTQYSGMQQPAVY----TAYSQTGQPYSLPTYDLGVMLPAIKTE 205
               S PA+   + +   +  SG+ + +       A +QTG P +L T DLG       + 
Sbjct: 2417 ---SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSS 2473

Query: 206  SGLSQTQSPLQSGCLSYSPGFSTP---QPGQTPYSYQMPGSSFAP-----SSTIY----- 252
            SG + T         S   G STP    P  T  +  +PGS   P     S+T Y     
Sbjct: 2474 SGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE-TTTLPGSPTTPSLSEKSTTFYTSPRS 2532

Query: 253  --ANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTY 310
              A  S + +T+   S++   S++  G      +  ++T       + T+  +P ST T 
Sbjct: 2533 PDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTT 2592

Query: 311  QL----------QESLPGLTNQPGEFDTMQSPST 334
             L          QES     + PG  DT  SP +
Sbjct: 2593 LLPASTTTSGPSQESTTS-HSSPGSTDTALSPGS 2625



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 84/336 (25%), Positives = 132/336 (39%), Gaps = 60/336 (17%)

Query: 40   TLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLL--A 97
            TL G   TPG S+   +  SS    T      +MT L   +   +  +   +T S +  A
Sbjct: 2787 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2846

Query: 98   VKTEPLNSSETTA--TTGDGALDT--FTGSVITS-SGYSPRSAHQYSPQLYPSKPYPHIL 152
              T P  S E+T   ++  G+ +T  F  S  TS  G  P + H                
Sbjct: 2847 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFH---------------- 2890

Query: 153  STPAAQTMSAYAGQTQYSGMQQPAVY----TAYSQTGQPYSLPTYDLG------------ 196
            S PA+   + +   +  SG+ + +       A +QTG P +L T DLG            
Sbjct: 2891 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 2950

Query: 197  ---VMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQ--TP----------YSYQMP 241
                + PA  T SGL    +P +   LS S   +T  PG   TP           S + P
Sbjct: 2951 TGTTLSPARSTTSGLVGESTPSR---LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP 3007

Query: 242  GSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-A 300
             ++ +P++T   ++ VS  ++ S SQ      TAF  +      S     ++ +  +T A
Sbjct: 3008 DATLSPATT--TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEA 3065

Query: 301  DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPI 336
              +P ST+   L +      + PG+ +T   P   I
Sbjct: 3066 TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 3101



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 82/336 (24%), Positives = 126/336 (37%), Gaps = 60/336 (17%)

Query: 40   TLVGGGDTPGSSKLEKS----------NLSSTSVTTNGTGGENMTVLNTADWLLSCNTPS 89
            TL G   TPG S+   +           LS  S+T+ G G E+ T  +      S  +P+
Sbjct: 1230 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 1289

Query: 90   SATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITS-SGYSPRSAHQYSPQLYPSKPY 148
            S T   L+ ++  + SS    + G      F  S  TS  G  P + H            
Sbjct: 1290 STTTPGLSEESTTVYSS----SRGSTETTVFPHSTTTSVHGEEPTTFH------------ 1333

Query: 149  PHILSTPAAQTMSAYAGQTQYSGMQQPAVY----TAYSQTGQPYSLPTYDLGVMLPAIKT 204
                S PA+   + +   +  SG+ + +       A +QTG P +L T DLG       +
Sbjct: 1334 ----SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 1389

Query: 205  ESGLSQTQSPLQSGCLSYSPGFSTP---QPGQTPYSYQMPGSSFAP-----SSTIY---- 252
             SG + T+        S   G STP    P  T  +  +PGS   P     S+T Y    
Sbjct: 1390 SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTE-TTTLPGSPTTPSLSEKSTTFYTSPR 1448

Query: 253  -----------ANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-A 300
                        ++ VS  ++ S SQ      TAF  +      S     ++ +  +T A
Sbjct: 1449 SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEA 1508

Query: 301  DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPI 336
              +P ST+   L +      + PG+ +T   P   I
Sbjct: 1509 TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 1544



 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 81/325 (24%), Positives = 119/325 (36%), Gaps = 38/325 (11%)

Query: 40   TLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLL--A 97
            TL G   TPG S+   +  SS    T      +MT L   +   +  +   +T S +  A
Sbjct: 3870 TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 3929

Query: 98   VKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPH--ILSTP 155
              T P  S E+T         T T     S+  S R   +  P  + S+P      L T 
Sbjct: 3930 STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVR---REEPTTFHSRPASTHTTLFTE 3986

Query: 156  AAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPL 215
             + T       T + G        A +QTG P +L T DLG       + SG + T+   
Sbjct: 3987 DSTTSGLTEESTAFPGSP------ASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSP 4040

Query: 216  QSGCLSYSPGFSTP---QPGQTPYSYQMPGSSFAP-----SSTIY--------------- 252
                 S   G STP    P  T  +  +PGS   P     S+T Y               
Sbjct: 4041 ARSTTSGLVGESTPSRLSPSSTE-TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATT 4099

Query: 253  ANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-ADGTPSSTSTYQ 311
             ++ VS  ++ S SQ      TAF  +      S     ++ +  +T A  +P ST+   
Sbjct: 4100 TSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASS 4159

Query: 312  LQESLPGLTNQPGEFDTMQSPSTPI 336
            L +      + PG+ +T   P   I
Sbjct: 4160 LGQQSTTFHSSPGDTETTLLPDDTI 4184



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 75/315 (23%), Positives = 119/315 (37%), Gaps = 40/315 (12%)

Query: 51  SKLEKSNLSSTSVTTNGTGGENMTVLNT-ADWLLSCNTPSSATMSLLAVKTEPLNSSETT 109
           S     +   ++V+ +G G    T+  + +   +    P ++ ++  +++T  L  S TT
Sbjct: 214 SSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTT 273

Query: 110 ATTGDGALD----------TFTGSVITSSGYSPRSAHQYSPQLYPSKPYP-HILSTPAAQ 158
           A   + +            T + +  TSSG S +S   +S      +P P H ++ P + 
Sbjct: 274 AGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHS------RPGPTHTIAFPDST 327

Query: 159 TMSAYAGQTQYSGMQQPAVYTAYSQ-TGQPYSL----------PTYDLGVMLPAIKTESG 207
           TM   + ++  S     +  T  S  T  P SL          P Y     LP   T SG
Sbjct: 328 TMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSG 387

Query: 208 LSQTQSPLQSGC----LSYSPGFSTPQPGQTPYSYQMPGS---SFAPSSTIYANNSVSNS 260
           L +  +P+ S       + SP  ST   G+       P S   S APS T  A   V  S
Sbjct: 388 LLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSA--FVKLS 445

Query: 261 TNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTS-TYQLQESLPGL 319
           T +  S    P+ T F  +     +S  +   + +   TA   P + S T    E     
Sbjct: 446 TTYHSSPSSTPT-THFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAY 504

Query: 320 TNQPGEFDTMQSPST 334
              PG   TM  P +
Sbjct: 505 HRSPGSTQTMHFPES 519



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 78/329 (23%), Positives = 125/329 (37%), Gaps = 49/329 (14%)

Query: 48   PGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSE 107
            P SS    + LS    TT+G  GE+     +     +   P S T       T  L+   
Sbjct: 1388 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT-------TPSLSEKS 1440

Query: 108  TTATTGDGALD-TFTGSVITSSGYSPRSAHQYS-PQLYPSKPYPHILSTP--AAQTMSAY 163
            TT  T   + D T + +  TSSG S  S+  +S P    +  +P   +T   + +  +++
Sbjct: 1441 TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSH 1500

Query: 164  AGQTQYSGMQQPAVYTAYS---QTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCL 220
            + Q        P   TA S   Q+   +S P      +LP     SGL +  +P  S   
Sbjct: 1501 SSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTG 1560

Query: 221  SY----SPGFSTPQ------------PGQTPYSYQMPGSSFAP---SSTIYANNSVSNST 261
            S     +P  ST              P  +  +   PG++ AP   S+T ++  S + +T
Sbjct: 1561 SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTT 1620

Query: 262  NFSGSQQD----------YPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGT------PS 305
            +FS S             + S  A G   +    + S      T++  + G+      P 
Sbjct: 1621 HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 1680

Query: 306  STSTYQLQESLPGLTNQPGEFDTMQSPST 334
            ST+T  L E      + P   DT  SP++
Sbjct: 1681 STTTAGLSEKSTTFYSSPRSPDTTLSPAS 1709



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 78/329 (23%), Positives = 125/329 (37%), Gaps = 49/329 (14%)

Query: 48   PGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSE 107
            P SS    + LS    TT+G  GE+     +     +   P S T       T  L+   
Sbjct: 2945 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT-------TPSLSEKS 2997

Query: 108  TTATTGDGALD-TFTGSVITSSGYSPRSAHQYS-PQLYPSKPYPHILSTP--AAQTMSAY 163
            TT  T   + D T + +  TSSG S  S+  +S P    +  +P   +T   + +  +++
Sbjct: 2998 TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASH 3057

Query: 164  AGQTQYSGMQQPAVYTAYS---QTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCL 220
            + Q        P   TA S   Q+   +S P      +LP     SGL +  +P  S   
Sbjct: 3058 SSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTG 3117

Query: 221  SY----SPGFSTPQ------------PGQTPYSYQMPGSSFAP---SSTIYANNSVSNST 261
            S     +P  ST              P  +  +   PG++ AP   S+T ++  S + +T
Sbjct: 3118 SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTT 3177

Query: 262  NFSGSQQD----------YPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGT------PS 305
            +FS S             + S  A G   +    + S      T++  + G+      P 
Sbjct: 3178 HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 3237

Query: 306  STSTYQLQESLPGLTNQPGEFDTMQSPST 334
            ST+T  L E      + P   DT  SP++
Sbjct: 3238 STTTAGLSEKSTTFYSSPRSPDTTLSPAS 3266



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 79/349 (22%), Positives = 128/349 (36%), Gaps = 51/349 (14%)

Query: 19   SDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS----------TSVTTNGT 68
            S+ S + +SR       A P +      TPG S+   ++ SS           S TT+G 
Sbjct: 2074 SEESTTSHSRPGSTHTTAFPDSTT----TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGP 2129

Query: 69   GGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSS 128
              E+ T  ++     +  +P S T      ++   +SS  +  T      T      TSS
Sbjct: 2130 SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHT------TLFPDSTTSS 2183

Query: 129  GYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQ---------YSGMQQPAVYT 179
            G    S   +S     S   P    +PA+ T     G++          ++    P+  T
Sbjct: 2184 GIVEASTRVHS-----STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 2238

Query: 180  AYSQTGQPY-----SLPTYDLGVMLPAIKTESGLSQTQ-----SPLQSGCLSYSPGFSTP 229
            A  +    Y     S PT       PA  T SG S+       SP  SG    S   +T 
Sbjct: 2239 APVEESTTYHRSPGSTPT----THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTS 2294

Query: 230  QPGQTPYSYQMPGSS---FAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS 286
              G++  S   PGS+     P ST     S +++T +S  +    + +            
Sbjct: 2295 GRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 2354

Query: 287  ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
            ++T  +   S ++     S+T+    +ES    ++ PG  +T   P TP
Sbjct: 2355 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTP 2403



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 73/315 (23%), Positives = 125/315 (39%), Gaps = 34/315 (10%)

Query: 62   SVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFT 121
            S TT+G G E+ T  ++    +S  +  S T +L+   T   +S  +TATT       F 
Sbjct: 3487 SDTTSGRGEESTTSHSSTTHTIS--SAPSTTSALVEEPTSYHSSPGSTATTH------FP 3538

Query: 122  GSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY 181
             S  T+SG S  S   +S     S+     +  PA  T S   G++  S +   ++ T  
Sbjct: 3539 DSS-TTSGRSEESTASHS-----SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 3592

Query: 182  --SQTGQP---------YSLPTYDLGVMLPAIKTESGLSQ--TQSPLQSGCLSYSPGF-- 226
                T  P         +S P      + PA  T SG+S+  T S  + G  +++  F  
Sbjct: 3593 LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGS-THTTAFPD 3651

Query: 227  STPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYS 286
            ST  PG + +S     S  +  +T+      +++T    SQ+   S+++ G    A    
Sbjct: 3652 STTTPGLSRHSTTSHSSPGSTDTTLLP----ASTTTSGSSQESTTSHSSSGSTDTALSPG 3707

Query: 287  ASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRS 346
            ++T  ++   + T   +P ST T    +S               S  +P   L   +  S
Sbjct: 3708 STTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTS 3767

Query: 347  SGSKSRGRGRKNNPS 361
             G +      + +P+
Sbjct: 3768 PGLQGESTAFQTHPA 3782



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 72/302 (23%), Positives = 114/302 (37%), Gaps = 54/302 (17%)

Query: 40   TLVGGGDTPG----------SSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPS 89
            TL     TPG          SS+     LS  S+T++   GE  ++ + A+   +   P+
Sbjct: 4867 TLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPA 4926

Query: 90   SATMSLLAVKTEPLN----SSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPS 145
            S T S L+ ++   +    S+ETT + G     +F     T       +    SP    S
Sbjct: 4927 STTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSP---AS 4983

Query: 146  KPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTE 205
               P +  +  + T  +  G T+ +        + +SQ   P+         +LPA  T 
Sbjct: 4984 TTVPGL--SEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTT 5041

Query: 206  SGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSG 265
            + + Q  +   S         S+   G TP    +P  S        A++ V   T F  
Sbjct: 5042 TDIGQESTAFHS---------SSDATGTTP----LPARS-------TASDLVGEPTTFYI 5081

Query: 266  SQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGT-PSSTSTYQLQESL----PGLT 320
            S    P+YT          + AS+  + +T  +T   T PS TST    ESL    PGL 
Sbjct: 5082 SPS--PTYTTL--------FPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLAPGLC 5131

Query: 321  NQ 322
             +
Sbjct: 5132 QE 5133



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 72/296 (24%), Positives = 110/296 (37%), Gaps = 58/296 (19%)

Query: 60   STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVK--TEPLNSSETTATTGDGAL 117
            S S TT G   E+ TV ++     +   P+ +  S+L  +  T P++S  T  T   G+ 
Sbjct: 1623 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 1682

Query: 118  DTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAV 177
                    T++G S +S   YS     S   P    +PA+ T S  + ++          
Sbjct: 1683 --------TTAGLSEKSTTFYS-----SPRSPDTTLSPASTTSSGVSEEST--------- 1720

Query: 178  YTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS--TPQPGQTP 235
             T++S+ G  ++          P   T  G+SQ  +   S     SPG +  T  PG T 
Sbjct: 1721 -TSHSRPGSTHT-------TAFPGSTTMPGVSQESTASHS-----SPGSTDTTLSPGSTT 1767

Query: 236  YSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMT 295
                   SS  P ST + ++  S  T            TA G  + +    +ST   + T
Sbjct: 1768 ------ASSLGPESTTFHSSPGSTETTLLPDNT-----TASGLLEASTPVHSSTGSPHTT 1816

Query: 296  SNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKS 351
             +     T    ST           + P   DTM +P T      E +  S GS S
Sbjct: 1817 LSPAGSTTRQGESTT--------FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS 1864



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 72/314 (22%), Positives = 123/314 (39%), Gaps = 32/314 (10%)

Query: 62   SVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFT 121
            S TT+G G E+ T  ++    +S  +  S T +L+   T   +S  +TATT       F 
Sbjct: 847  SDTTSGRGEESTTSHSSTTHTIS--SAPSTTSALVEEPTSYHSSPGSTATTH------FP 898

Query: 122  GSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY 181
             S  T+SG S  S   +S     S+     +  PA  T S   G++  S +   ++ T  
Sbjct: 899  DSS-TTSGRSEESTASHS-----SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 952

Query: 182  --SQTGQP---------YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS-YSPGF--S 227
                T  P         +S P      + PA  T SG+S+  +  +S   S ++  F  S
Sbjct: 953  LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDS 1012

Query: 228  TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 287
            T  PG + +S     S  +  +T+      +++T    SQ+   S+++ G    A    +
Sbjct: 1013 TTTPGLSRHSTTSHSSPGSTDTTLLP----ASTTTSGPSQESTTSHSSSGSTDTALSPGS 1068

Query: 288  STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSS 347
            +T  ++   + T    P ST T    +S               S  +P   L   +  S 
Sbjct: 1069 TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 1128

Query: 348  GSKSRGRGRKNNPS 361
            G +      + +P+
Sbjct: 1129 GLQGESTAFQTHPA 1142



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 69/285 (24%), Positives = 107/285 (37%), Gaps = 49/285 (17%)

Query: 48   PGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSE 107
            PGS    ++ L +T +TT   G E+ T  +++    +  +P+ +T S L  ++ P   S 
Sbjct: 2918 PGSPASTQTGLPAT-LTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSP 2976

Query: 108  TTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQT 167
            ++  T      T  GS  T S        + S   Y S   P    +PA  T S  + ++
Sbjct: 2977 SSTET-----TTLPGSPTTPS------LSEKSTTFYTSPRSPDATLSPATTTSSGVSEES 3025

Query: 168  QYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS 227
                       T++SQ G  ++          P   T SGLSQ             P  S
Sbjct: 3026 S----------TSHSQPGSTHT-------TAFPDSTTTSGLSQ------------EPTAS 3056

Query: 228  TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 287
                G T        ++ +P ST  A++    ST F  S  D  +         +    A
Sbjct: 3057 HSSQGSTE-------ATLSPGSTT-ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEA 3108

Query: 288  STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSP 332
            ST     T +     TP+S+++  LQE      + P   DT  SP
Sbjct: 3109 STPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 3153



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 70/268 (26%), Positives = 107/268 (39%), Gaps = 28/268 (10%)

Query: 60   STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVK--TEPLNSSETTATTGDGAL 117
            S S TT G   E+ TV ++     +   P+ +  S+L  +  T P++S  T  T   G+ 
Sbjct: 3180 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 3239

Query: 118  DTFTGSVITSSGYS-PRSAHQ-YSPQLYPSKPYPHILST----PAAQTMSAYAGQTQYSG 171
             T   S  +++ YS PRS     SP    S       +T    P +   +A+ G T   G
Sbjct: 3240 TTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 3299

Query: 172  MQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS--TP 229
            + Q +  +  S    P S  T     + P   T S L    +   SG     PG +  T 
Sbjct: 3300 VSQESTASHSS----PGSTDT----TLSPGSTTASSLGPESTTFHSG-----PGSTETTL 3346

Query: 230  QPGQTPYSYQMPGSSFAPSSTIYANNSVS--NSTNFSGSQQDYPSYTAFGQNQYAQYYSA 287
             P  T  S  +  S+   SST   + ++S   ST   G    + S+        A     
Sbjct: 3347 LPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP---P 3403

Query: 288  STYGAYMTSNNTADGTPSSTSTYQLQES 315
            +T  A++  + T+ G+PSST T     S
Sbjct: 3404 TTTSAFVELSTTSHGSPSSTPTTHFSAS 3431



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 68/273 (24%), Positives = 108/273 (39%), Gaps = 38/273 (13%)

Query: 60   STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVK--TEPLNSSETTATTGDGAL 117
            S S TT G   E+ TV ++     +   P+ +  S+L  +  T P++S  T  T   G+ 
Sbjct: 4263 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 4322

Query: 118  DTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAV 177
                    T++G S +S   YS     S   P    +PA+ T S  + ++  S  +  ++
Sbjct: 4323 --------TTAGLSEKSTTFYS-----SPRSPDTTLSPASTTSSGVSEESTTSHSRPGSM 4369

Query: 178  YTAY--SQTGQP---------YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGF 226
            +T    S T  P         +S P      + P   T S L    +   S     SPG 
Sbjct: 4370 HTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS-----SPGS 4424

Query: 227  S--TPQPGQTPYSYQMPGSSFAPSSTIYANNSVS--NSTNFSGSQQDYPSYTAFGQNQYA 282
            +  T  P  T  S  +  S+   SST   + ++S   ST   G    + S+        A
Sbjct: 4425 TETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPA 4484

Query: 283  QYYSASTYGAYMTSNNTADGTPSSTSTYQLQES 315
                 +T  A++  + T+ G+PSST T     S
Sbjct: 4485 P---PTTTSAFVELSTTSHGSPSSTPTTHFSAS 4514



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 78/324 (24%), Positives = 115/324 (35%), Gaps = 45/324 (13%)

Query: 48   PGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNT-PSSATMSLLAVKTEPLNS- 105
            PGS+    S +S  S TT G   E+ TV +++         P S T S+   +    +S 
Sbjct: 1279 PGSTH---STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSR 1335

Query: 106  ---SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILST-------- 154
               + TT  T D      T       G SP S     P    +       +T        
Sbjct: 1336 PASTHTTLFTEDSTTSGLTEESTAFPG-SPASTQTGLPATLTTADLGEESTTFPSSSGST 1394

Query: 155  -----PAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQP------------YSLPTYDLGV 197
                 PA  T S   G++  S +   +  T  +  G P            Y+ P      
Sbjct: 1395 GTKLSPARSTTSGLVGESTPSRLSPSSTETT-TLPGSPTTPSLSEKSTTFYTSPRSPDAT 1453

Query: 198  MLPAIKTESGLSQTQS-----PLQSGCLSYSPGFSTPQPGQTPY-SYQMPGSSFA---PS 248
            + PA  T SG+S+  S     P  +   ++    +T    Q P  S+   GS+ A   P 
Sbjct: 1454 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPG 1513

Query: 249  STIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTS 308
            ST  A++    ST F  S  D  +         +    AST     T +     TP+S++
Sbjct: 1514 STT-ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASST 1572

Query: 309  TYQLQESLPGLTNQPGEFDTMQSP 332
            +  LQE      + P   DT  SP
Sbjct: 1573 SAGLQEESTTFQSWPSSSDTTPSP 1596



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 77/356 (21%), Positives = 123/356 (34%), Gaps = 60/356 (16%)

Query: 48   PGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNT-PSSATMSLLAVKTEPLNS- 105
            PGS+    S +S  S TT G   E+ TV +++         P + T S+   +    +S 
Sbjct: 2362 PGSTH---STVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSR 2418

Query: 106  ---SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILST-------- 154
               + TT  T D      T       G SP S     P    +       +T        
Sbjct: 2419 PASTHTTLFTEDSTTSGLTEESTAFPG-SPASTQTGLPATLTTADLGEESTTFPSSSGST 2477

Query: 155  -----PAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQP------------YSLPTYDLGV 197
                 PA  T S   G++  S +   +  T  +  G P            Y+ P      
Sbjct: 2478 GTTLSPARSTTSGLVGESTPSRLSPSSTETT-TLPGSPTTPSLSEKSTTFYTSPRSPDAT 2536

Query: 198  MLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSV 257
            + PA  T SG+S+  S   S            QPG T ++   P S+  P  + ++  S 
Sbjct: 2537 LSPATTTSSGVSEESSTSHS------------QPGST-HTTAFPDSTTTPGLSRHSTTSH 2583

Query: 258  SN-----------STNFSG-SQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPS 305
            S+           ST  SG SQ+   S+++ G    A    ++T  ++   + T   +P 
Sbjct: 2584 SSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPG 2643

Query: 306  STSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNPS 361
            ST T    +S               S  +P   L   +  S G +      + +P+
Sbjct: 2644 STHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPA 2699



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 68/318 (21%), Positives = 114/318 (35%), Gaps = 21/318 (6%)

Query: 37   SPHTLVGGGDTPGSSKLEKSNLSST------------SVTTNGTGGENMTVLNTADWLLS 84
            SP   +    T  S   E+S+ S +            S TT+G   E  T  ++     +
Sbjct: 4089 SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEA 4148

Query: 85   CNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYP 144
              +P S T S L  ++   +SS     T     DT T  ++ +S  +  S       L P
Sbjct: 4149 TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTP 4208

Query: 145  SKPYPHILSTPAAQTMS-AYAGQTQYSGMQQPAVYTAYSQT--GQPYSLPTYDLGVMLPA 201
            +      L   +    S   +  T  S     AV    S T   +P S PT         
Sbjct: 4209 ASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTT 4268

Query: 202  I-KTESGLSQTQSPLQSGCLSYSPGFSTP----QPGQTPYSYQMPGSSFAPSSTIYANNS 256
            + ++E   +   SP  +G   +    +T     +P  +P S     ++  P ST  A  S
Sbjct: 4269 LGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS 4328

Query: 257  VSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESL 316
              ++T +S  +    + +            ++T  +   S +T    PSST+   + +  
Sbjct: 4329 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTT-AFPSSTTMPGVSQES 4387

Query: 317  PGLTNQPGEFDTMQSPST 334
                + PG  DT  SP +
Sbjct: 4388 TASHSSPGSTDTTLSPGS 4405



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 70/343 (20%), Positives = 121/343 (35%), Gaps = 38/343 (11%)

Query: 4    SQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEK---SNLSS 60
            SQD     V    + + V   +++ S           L G   TPG S+      S+ SS
Sbjct: 4639 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSS 4698

Query: 61   T-------SVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTG 113
            T       S TT G   E+ TV ++     +  +P+ +T S L  ++   +SS  +  T 
Sbjct: 4699 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTM 4758

Query: 114  DGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQ 173
                 +      T+SG S  S   +S          H +S+P + T +     T Y    
Sbjct: 4759 HFPESS------TASGRSEESRTSHSSTT-------HTISSPPSTTSALVEEPTSYHSSP 4805

Query: 174  QPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTP-QPG 232
                 T + ++                  ++E   +   SP  +G       F+T  +  
Sbjct: 4806 GSIATTHFPESSTTSG-------------RSEESTASHSSPDTNGITPLPAHFTTSGRIA 4852

Query: 233  QTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGA 292
            ++   Y  PGS     ++      +S  +    S    P  T    +  +   S      
Sbjct: 4853 ESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSL 4912

Query: 293  YMTSNNT-ADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPST 334
            Y  + +T     P+ST+T  L +      ++PG  +T  SP +
Sbjct: 4913 YSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGS 4955


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 82/336 (24%), Positives = 126/336 (37%), Gaps = 60/336 (17%)

Query: 40   TLVGGGDTPGSSKLEKS----------NLSSTSVTTNGTGGENMTVLNTADWLLSCNTPS 89
            TL G   TPG S+   +           LS  S+T+ G G E+ T  +      S  +P+
Sbjct: 717  TLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 776

Query: 90   SATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITS-SGYSPRSAHQYSPQLYPSKPY 148
            S T   L+ ++  + SS    + G      F  S  TS  G  P + H            
Sbjct: 777  STTTPGLSEESTTVYSS----SRGSTETTVFPHSTTTSVHGEEPTTFH------------ 820

Query: 149  PHILSTPAAQTMSAYAGQTQYSGMQQPAVY----TAYSQTGQPYSLPTYDLGVMLPAIKT 204
                S PA+   + +   +  SG+ + +       A +QTG P +L T DLG       +
Sbjct: 821  ----SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPS 876

Query: 205  ESGLSQTQSPLQSGCLSYSPGFSTP---QPGQTPYSYQMPGSSFAP-----SSTIY---- 252
             SG + T+        S   G STP    P  T  +  +PGS   P     S+T Y    
Sbjct: 877  SSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTE-TTTLPGSPTTPSLSEKSTTFYTSPR 935

Query: 253  -----------ANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-A 300
                        ++ VS  ++ S SQ      TAF  +      S     ++ +  +T A
Sbjct: 936  SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEA 995

Query: 301  DGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPI 336
              +P ST+   L +      + PG+ +T   P   I
Sbjct: 996  TLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 1031



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 78/329 (23%), Positives = 125/329 (37%), Gaps = 49/329 (14%)

Query: 48   PGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSE 107
            P SS    + LS    TT+G  GE+     +     +   P S T       T  L+   
Sbjct: 875  PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT-------TPSLSEKS 927

Query: 108  TTATTGDGALD-TFTGSVITSSGYSPRSAHQYS-PQLYPSKPYPHILSTP--AAQTMSAY 163
            TT  T   + D T + +  TSSG S  S+  +S P    +  +P   +T   + +  +++
Sbjct: 928  TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSH 987

Query: 164  AGQTQYSGMQQPAVYTAYS---QTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCL 220
            + Q        P   TA S   Q+   +S P      +LP     SGL +  +P  S   
Sbjct: 988  SSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTG 1047

Query: 221  SY----SPGFSTPQ------------PGQTPYSYQMPGSSFAP---SSTIYANNSVSNST 261
            S     +P  ST              P  +  +   PG++ AP   S+T ++  S + +T
Sbjct: 1048 SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTT 1107

Query: 262  NFSGSQQD----------YPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGT------PS 305
            +FS S             + S  A G   +    + S      T++  + G+      P 
Sbjct: 1108 HFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPG 1167

Query: 306  STSTYQLQESLPGLTNQPGEFDTMQSPST 334
            ST+T  L E      + P   DT  SP++
Sbjct: 1168 STTTAGLSEKSTTFYSSPRSPDTTLSPAS 1196



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 72/296 (24%), Positives = 110/296 (37%), Gaps = 58/296 (19%)

Query: 60   STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVK--TEPLNSSETTATTGDGAL 117
            S S TT G   E+ TV ++     +   P+ +  S+L  +  T P++S  T  T   G+ 
Sbjct: 1110 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGST 1169

Query: 118  DTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAV 177
                    T++G S +S   YS     S   P    +PA+ T S  + ++          
Sbjct: 1170 --------TTAGLSEKSTTFYS-----SPRSPDTTLSPASTTSSGVSEEST--------- 1207

Query: 178  YTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFS--TPQPGQTP 235
             T++S+ G  ++          P   T  G+SQ  +   S     SPG +  T  PG T 
Sbjct: 1208 -TSHSRPGSTHT-------TAFPGSTTMPGVSQESTASHS-----SPGSTDTTLSPGSTT 1254

Query: 236  YSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMT 295
                   SS  P ST + ++  S  T            TA G  + +    +ST   + T
Sbjct: 1255 ------ASSLGPESTTFHSSPGSTETTLLPDNT-----TASGLLEASTPVHSSTGSPHTT 1303

Query: 296  SNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGSKS 351
             +     T    ST           + P   DTM +P T      E +  S GS S
Sbjct: 1304 LSPAGSTTRQGESTT--------FQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS 1351



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 72/314 (22%), Positives = 123/314 (39%), Gaps = 32/314 (10%)

Query: 62  SVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFT 121
           S TT+G G E+ T  ++    +S  +  S T +L+   T   +S  +TATT       F 
Sbjct: 334 SDTTSGRGEESTTSHSSTTHTIS--SAPSTTSALVEEPTSYHSSPGSTATTH------FP 385

Query: 122 GSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAY 181
            S  T+SG S  S   +S     S+     +  PA  T S   G++  S +   ++ T  
Sbjct: 386 DSS-TTSGRSEESTASHS-----SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 439

Query: 182 --SQTGQP---------YSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS-YSPGF--S 227
               T  P         +S P      + PA  T SG+S+  +  +S   S ++  F  S
Sbjct: 440 LPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDS 499

Query: 228 TPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSA 287
           T  PG + +S     S  +  +T+      +++T    SQ+   S+++ G    A    +
Sbjct: 500 TTTPGLSRHSTTSHSSPGSTDTTLLP----ASTTTSGPSQESTTSHSSSGSTDTALSPGS 555

Query: 288 STYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSS 347
           +T  ++   + T    P ST T    +S               S  +P   L   +  S 
Sbjct: 556 TTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 615

Query: 348 GSKSRGRGRKNNPS 361
           G +      + +P+
Sbjct: 616 GLQGESTAFQTHPA 629



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 78/324 (24%), Positives = 115/324 (35%), Gaps = 45/324 (13%)

Query: 48   PGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNT-PSSATMSLLAVKTEPLNS- 105
            PGS+    S +S  S TT G   E+ TV +++         P S T S+   +    +S 
Sbjct: 766  PGSTH---STVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSR 822

Query: 106  ---SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILST-------- 154
               + TT  T D      T       G SP S     P    +       +T        
Sbjct: 823  PASTHTTLFTEDSTTSGLTEESTAFPG-SPASTQTGLPATLTTADLGEESTTFPSSSGST 881

Query: 155  -----PAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQP------------YSLPTYDLGV 197
                 PA  T S   G++  S +   +  T  +  G P            Y+ P      
Sbjct: 882  GTKLSPARSTTSGLVGESTPSRLSPSSTETT-TLPGSPTTPSLSEKSTTFYTSPRSPDAT 940

Query: 198  MLPAIKTESGLSQTQS-----PLQSGCLSYSPGFSTPQPGQTPY-SYQMPGSSFA---PS 248
            + PA  T SG+S+  S     P  +   ++    +T    Q P  S+   GS+ A   P 
Sbjct: 941  LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPG 1000

Query: 249  STIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTS 308
            ST  A++    ST F  S  D  +         +    AST     T +     TP+S++
Sbjct: 1001 STT-ASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASST 1059

Query: 309  TYQLQESLPGLTNQPGEFDTMQSP 332
            +  LQE      + P   DT  SP
Sbjct: 1060 SAGLQEESTTFQSWPSSSDTTPSP 1083


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 78/320 (24%), Positives = 132/320 (41%), Gaps = 25/320 (7%)

Query: 47   TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNT--ADWLLSCNTPSSATMSLLAVKTEPLN 104
            TPG++ +  + L++T+ TT  TG    T  +T    W+L+    ++AT+++    T   +
Sbjct: 4417 TPGTTWI-LTELTTTATTTASTGS-TATPSSTPGTTWILT-EPSTTATVTVPTGSTATAS 4473

Query: 105  SSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKP-YPHILSTPAAQTMSAY 163
            S++ TA T   +  T T   +TSS  +P S    SP    + P      +TP A + +A 
Sbjct: 4474 STQATAGTPHVST-TATTPTVTSSKATPSS----SPGTATALPALRSTATTPTATSFTAI 4528

Query: 164  AGQ---TQYSGMQQPAVYTAYSQTGQPYSLP-TYDLGVMLPAIKTESGLSQTQSPLQS-- 217
                  T ++ + Q    TA   T  P S P T     +L A  T +G + + +   S  
Sbjct: 4529 PSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTP 4588

Query: 218  GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
            G    +   +T   G T      PG++  P   I    + + +T  +      PS +  G
Sbjct: 4589 GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPS-SIPG 4647

Query: 278  QNQYAQYYSASTYG------AYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQS 331
                A+  + +T        A  +S+    GTP S +T     +  G T  P       +
Sbjct: 4648 TTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSS-TPGTT 4706

Query: 332  PSTPIKDLDERTCRSSGSKS 351
            P TP+      T  ++ SK+
Sbjct: 4707 PITPVLTSTATTPAATSSKA 4726



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 76/333 (22%), Positives = 120/333 (36%), Gaps = 40/333 (12%)

Query: 36   ASPHTLVGGGDTPGSSK-----LEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSS 90
            A+  T++    TP SS      L     ++T+ T         + L TA   LS  T  +
Sbjct: 3203 ATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPT 3262

Query: 91   ATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPH 150
            ATMS     + P     +T  T        TGSV T S  +P +AH       P+     
Sbjct: 3263 ATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSS-TPGTAHTTK---VPTTTTTG 3318

Query: 151  ILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLP----------TYDLGVMLP 200
              +TP++   +A       S    P   T    T  P S+P          T    V   
Sbjct: 3319 FTATPSSSPGTALTPPVWISTTTTP---TTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 3375

Query: 201  AIKTESGLSQTQS---PLQSGCLSYSPGFSTPQPGQTPYSYQMP-------------GSS 244
            ++ T S  +QT      L +   + +   ST  P  TP +  +P              S+
Sbjct: 3376 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSST 3435

Query: 245  FAPSSTIYANNS--VSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADG 302
              PSS +   ++  V N+T  +  +   PS     +  +    S      ++T  +T   
Sbjct: 3436 VTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS 3495

Query: 303  TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
               + +T   Q S P L++      T +SP +P
Sbjct: 3496 HTPAATTSTTQHSTPALSSPHPSSRTTESPPSP 3528



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 71/294 (24%), Positives = 108/294 (36%), Gaps = 40/294 (13%)

Query: 47   TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
            TPG++   K   ++T+  T        T L    W+ +  TP++ T +       P +  
Sbjct: 4587 TPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIP 4646

Query: 107  ETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQ 166
             TT T     L T T +V T S  +P S+ Q S              TP + T +A    
Sbjct: 4647 GTTHTA--RVLTTTTTTVATGSMATPSSSTQTS-------------GTPPSLTTTA---- 4687

Query: 167  TQYSGMQQPAVYTAYSQTGQPYSLP-TYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPG 225
                        TA   T  P S P T  +  +L +  T    + +++   S     SP 
Sbjct: 4688 ---------TTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSS-----SPR 4733

Query: 226  FSTPQPGQTPYSYQMPGSSFA--PSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQ 283
             +T  P  T  + +   +SF   PSST++   +V   T    S       ++  +  +  
Sbjct: 4734 TATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTS 4793

Query: 284  YYSASTYGAYMTSNNTADGTPSST--STYQLQESLPGLTNQPGEFDTMQSPSTP 335
                +T  A MT    +  TPSST  +T  L E     T       T    STP
Sbjct: 4794 TVLTTT--ATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTP 4845



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 79/349 (22%), Positives = 125/349 (35%), Gaps = 42/349 (12%)

Query: 58   LSSTSVTTNGTGGENM--TVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDG 115
            L ST+ T   T    +  + L T    LS  T  +ATMS     + P  +  +T  T   
Sbjct: 3785 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTA 3844

Query: 116  ALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQP 175
                 TGSV T S  +P +AH       P+        TP++   +A       S    P
Sbjct: 3845 TTTRATGSVATPSS-TPGTAHTTK---VPTTTTTGFTVTPSSSPGTARTPPVWISTTTTP 3900

Query: 176  AVYTAYSQTGQPYSLP----------TYDLGVMLPAIKTESGLSQTQS---PLQSGCLSY 222
               T    T  P S+P          T    V   ++ T S  +QT      L +   + 
Sbjct: 3901 ---TTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTI 3957

Query: 223  SPGFSTPQPGQTPYSYQMP-------------GSSFAPSSTIYANNS--VSNSTNFSGSQ 267
            +   ST  P  TP +  +P              S+  PSS +   ++  V N+T  +  +
Sbjct: 3958 TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGR 4017

Query: 268  QDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFD 327
               PS     +  +    S +    ++T  +T      + +T   Q S P L++      
Sbjct: 4018 SLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSR 4077

Query: 328  TMQSPSTPIKDLDERTCRSS-----GSKSRGRGRKNNPSPPPDSDLERV 371
            T +SP +P       T  +S      + S+ R     PS P  + +  V
Sbjct: 4078 TTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 4126



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 75/346 (21%), Positives = 121/346 (34%), Gaps = 40/346 (11%)

Query: 36   ASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTAD----WL-LSCNTPSS 90
            A+  T+     TP SS    + L +   T       + T + ++     W  LS  T  +
Sbjct: 4488 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPT 4547

Query: 91   ATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPH 150
            ATMS     + P     +T  T        TGSV T S  +P +AH       P+     
Sbjct: 4548 ATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSS-TPGTAHTTK---VPTTTTTG 4603

Query: 151  ILSTPAAQTMSAYAGQTQYSGMQQPAVY--TAYSQTGQPYSLPTYDLGVMLPAIKTESGL 208
              +TP++   +A       S    P     T    T  P S+P            T   L
Sbjct: 4604 FTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIP--------GTTHTARVL 4655

Query: 209  SQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQ 268
            + T + + +G ++ +P  ST   G  P       S    ++TI A  S +N ++  G+  
Sbjct: 4656 TTTTTTVATGSMA-TPSSSTQTSGTPP-------SLTTTATTITATGSTTNPSSTPGTTP 4707

Query: 269  DYPSYTAFGQNQYAQYYSASTYG------------AYMTSNNTADGTPSSTSTYQLQESL 316
              P  T+      A    A++              +  T +     TP  +ST     ++
Sbjct: 4708 ITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTV 4767

Query: 317  PGLTNQP-GEFDTMQSPSTPIKDLDERTCRSSGSKSRGRGRKNNPS 361
            P  T  P     T+ + STP          ++ + +R       PS
Sbjct: 4768 PAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPS 4813



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 84/374 (22%), Positives = 135/374 (36%), Gaps = 45/374 (12%)

Query: 36   ASPHTLVGGGDTPGSSKLEKSNLS---STSVTTNGTGGENM--TVLNTADWLLSCNTPSS 90
            A+  T+     TP SS    + L    ST+ T   T    +  + L T    LS  T  +
Sbjct: 1946 ATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPT 2005

Query: 91   ATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPH 150
            ATMS     + P  +  +T  T        TGSV T S  +P +AH       P+     
Sbjct: 2006 ATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSS-TPGTAHTTK---VPTTTTTG 2061

Query: 151  ILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLP----------TYDLGVMLP 200
              +TP++   +A       S    P   T    T  P S+P          T    V   
Sbjct: 2062 FTATPSSSPGTALTPPVWISTTTTP---TTRGSTVTPSSIPGTTHTATVLTTTTTTVATG 2118

Query: 201  AIKTESGLSQTQS---PLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSV 257
            ++ T S  +QT      L +   + +   ST  P  TP +  +P      ++T  A ++ 
Sbjct: 2119 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNT 2178

Query: 258  SNSTNFSGSQQDYP-----------SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSS 306
               ++  G+    P           S      +     ++++T G   T++ T   T +S
Sbjct: 2179 VTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS 2238

Query: 307  ----TSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSS-----GSKSRGRGRK 357
                 +T   Q S P L++      T +SP +P       T  +S      + S+ R   
Sbjct: 2239 HTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTST 2298

Query: 358  NNPSPPPDSDLERV 371
              PS P  + +  V
Sbjct: 2299 LLPSSPTSAPITTV 2312



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 68/302 (22%), Positives = 111/302 (36%), Gaps = 25/302 (8%)

Query: 58   LSSTSVTTNGTGGENM--TVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDG 115
            L ST+ T   T    +  + L T    LS  T  +ATMS     + P     +T  T   
Sbjct: 2528 LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTA 2587

Query: 116  ALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTP--AAQTMSAYAGQTQYSGMQ 173
                 TGSV T S  +P +AH        +  +    S+    A+T+  +   T     +
Sbjct: 2588 TTTGATGSVATPSS-TPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTR 2646

Query: 174  QPAVYTAY--SQTGQPYSLPTYDLGVMLPAIKTESGLSQTQS---PLQSGCLSYSPGFST 228
               V  +     T  P  L T    V   ++ T S  +QT      L +   + +   ST
Sbjct: 2647 GSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 2706

Query: 229  PQPGQTPYSYQMP-------------GSSFAPSSTIYANNS--VSNSTNFSGSQQDYPSY 273
              P  TP +  +P              S+  PSS +   ++  V N+T  +  +   PS 
Sbjct: 2707 TNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSS 2766

Query: 274  TAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPS 333
                +  +    S +    ++T  +T      + +T   Q S P L++      T +SP 
Sbjct: 2767 PHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPP 2826

Query: 334  TP 335
            +P
Sbjct: 2827 SP 2828



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 60/259 (23%), Positives = 101/259 (38%), Gaps = 21/259 (8%)

Query: 84   SCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFT------GSVITSSGYSPR-SAH 136
            S  TPSS T     + T+P  ++ TTA+TG  A  T T        V+T++  +P  ++ 
Sbjct: 1896 STATPSS-TPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSS 1954

Query: 137  QYSPQLYP--SKPYPHILSTPAAQTMSAYAG------QTQYSGMQQPAVYTAYSQTGQPY 188
            + +P   P  +   P + ST    T ++          T ++ + Q    TA   T  P 
Sbjct: 1955 KATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPS 2014

Query: 189  SLP-TYDLGVMLPAIKTESGLSQTQSPLQS--GCLSYSPGFSTPQPGQTPYSYQMPGSSF 245
            S P T     +L A  T +G + + +   S  G    +   +T   G T      PG++ 
Sbjct: 2015 STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL 2074

Query: 246  APSSTIYANNS-VSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTP 304
             P   I    +  +  +  + S     ++TA          +  +     +S  T+ GTP
Sbjct: 2075 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS-GTP 2133

Query: 305  SSTSTYQLQESLPGLTNQP 323
             S +T     +  G T  P
Sbjct: 2134 PSLTTTATTITATGSTTNP 2152



 Score = 33.9 bits (76), Expect = 0.47
 Identities = 45/185 (24%), Positives = 74/185 (40%), Gaps = 34/185 (18%)

Query: 84   SCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLY 143
            S  TPSS T     + TE   ++ TTATTG  A+ + T       G +P           
Sbjct: 2982 STATPSS-TPGTTWILTEQTTAATTTATTGSTAIPSST------PGTAP----------- 3023

Query: 144  PSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAV-YTAYSQTGQPYS-LPTYDLGVMLPA 201
            P K      +TP A +  A +  +  +    P +  TA   T   ++ +P++ LG     
Sbjct: 3024 PPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGT---- 3079

Query: 202  IKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNST 261
              T +   QT +P+ +         ST  P  TP +          ++T  A +S+S  +
Sbjct: 3080 --TGTLPEQTTTPMAT--------MSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPS 3129

Query: 262  NFSGS 266
            +  G+
Sbjct: 3130 STPGT 3134



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 33/127 (25%), Positives = 52/127 (40%), Gaps = 21/127 (16%)

Query: 226  FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYY 285
            FSTPQP  +P      G + AP ++  A  ++S            P YT+          
Sbjct: 1631 FSTPQPTSSP------GLTRAPPASTTAVPTLSEGLTS-------PRYTS-------TLG 1670

Query: 286  SASTYGAYMTSNNTADGTPS-STSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTC 344
            +A+T G    + +T    P  +TST   + +LPG T   G +   Q P+     +     
Sbjct: 1671 TATTGGPTTPAGSTEPTVPGVATSTLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRA 1730

Query: 345  RSSGSKS 351
            R +G+ S
Sbjct: 1731 RPTGTAS 1737



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 76/360 (21%), Positives = 132/360 (36%), Gaps = 47/360 (13%)

Query: 4    SQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGG-GDTPGSSKLEKSNLSSTS 62
            S      S  +T T   V  S  ++S        P + +G  G  P  +    + +S+  
Sbjct: 4296 SSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIH 4355

Query: 63   VTTNGTGGENMTVLNTADWLL----SCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++        TVL T         S +TPSS T     + TE   ++ TTA TG  A  
Sbjct: 4356 PSSTPETTHTSTVLTTKATTTRATSSTSTPSS-TPGTTWILTELTTAATTTAATGPTATP 4414

Query: 119  TFT-------GSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPA-AQTMSAYAGQTQYS 170
            + T         + T++  +  +    +P   P   +  IL+ P+   T++   G T  +
Sbjct: 4415 SSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTW--ILTEPSTTATVTVPTGSTATA 4472

Query: 171  GMQQPAVYTAY-----------SQTGQPYSLPTYDLGVMLPAIK----TESGLSQTQSPL 215
               Q    T +           S    P S P       LPA++    T +  S T  P 
Sbjct: 4473 SSTQATAGTPHVSTTATTPTVTSSKATPSSSP--GTATALPALRSTATTPTATSFTAIPS 4530

Query: 216  QSGCLSY---------SPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSG- 265
             S   ++         +   ST  P  TP +        A ++T  A  SV+  ++  G 
Sbjct: 4531 SSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGT 4590

Query: 266  ---SQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT-ADGTPSSTSTYQLQESLPGLTN 321
               ++    + T F     +   +A T   ++++  T    TP+++ +     S+PG T+
Sbjct: 4591 AHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTH 4650



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 68/290 (23%), Positives = 99/290 (34%), Gaps = 49/290 (16%)

Query: 47   TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTP----SSATMSLLAVKTE- 101
            TPG++   K   ++T+  T        T      W+ +  TP    S+ T S +   T  
Sbjct: 3859 TPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTTHT 3918

Query: 102  PLNSSETTATTGDGALDTFTG---------SVITSSGYSPRSAHQYSPQLYP-SKPYPHI 151
            P   + TT T   G++ T +          S+IT++     +    +P   P + P P +
Sbjct: 3919 PTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNPSSTPGTTPIPPV 3978

Query: 152  LSTPA---AQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESG- 207
            L+T A   A T S     +       P V    + T      P+    V        SG 
Sbjct: 3979 LTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGT 4038

Query: 208  LSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQ 267
            L  T     S   S++P  +T   G T +S     S    S T  +  S   +T      
Sbjct: 4039 LGTTHITEPSTGTSHTPAATT---GTTQHSTPALSSPHPSSRTTESPPSPGTTT------ 4089

Query: 268  QDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLP 317
               P +T                    TS  TA  TPS T T  L  S P
Sbjct: 4090 ---PGHTT------------------ATSRTTATATPSKTRTSTLLPSSP 4118


>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
           sapiens]
          Length = 661

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 92/310 (29%), Positives = 120/310 (38%), Gaps = 58/310 (18%)

Query: 106 SETTATTGDGALDTFTGSVI----TSSGY-SPRSAHQYSP--QLYPSKPYPHILSTPAAQ 158
           ++TTAT G  A  T  G       TS+GY +P +   YS   Q Y +  Y    +T    
Sbjct: 55  AQTTATYGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTAT-VTT 113

Query: 159 TMSAYAGQTQYSGMQQPAVYTAYSQTGQP-YSLPTYDLGVMLPAIKTESGLSQT----QS 213
           T ++YA Q+ Y    QPA Y AY Q  QP  + PT       P  +T    S T    Q 
Sbjct: 114 TQASYAAQSAYG--TQPA-YPAYGQ--QPAATAPTRPQDGNKPT-ETSQPQSSTGGYNQP 167

Query: 214 PLQSGCLSYS----PGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFS----- 264
            L  G  +YS    PG    QP   P SY  P S  +   T Y  +S S    +      
Sbjct: 168 SLGYGQSNYSYPQVPGSYPMQPVTAPPSYP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSY 226

Query: 265 GSQQDYPSYTAFGQNQYAQY------YS------ASTYGAYMTSNNTADGTPSSTSTYQL 312
           G Q  Y   +++GQ     Y      YS      +    +Y   ++     PSS   Y  
Sbjct: 227 GQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG- 285

Query: 313 QESLPGLTNQPGEFDTMQSPSTPIKDLD--ERTCRSSGSKSRGRGRK--------NNPSP 362
           QES  G  + PGE  +M  P    +     +R   S G +  GRG          N P  
Sbjct: 286 QES--GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGAGERGGFNKPGG 343

Query: 363 P----PDSDL 368
           P    PD DL
Sbjct: 344 PMDEGPDLDL 353


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 69/275 (25%), Positives = 101/275 (36%), Gaps = 44/275 (16%)

Query: 42   VGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTE 101
            VG G TPG++    S  S  S  + G          +  W  +  +P S           
Sbjct: 1535 VGSGMTPGAAGFSPSAASDASGFSPGY---------SPAWSPTPGSPGS----------- 1574

Query: 102  PLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQ---LYPSKPYPHILSTPAAQ 158
            P  SS    + G     +++    TS  Y PRS   Y+PQ     P+ P     S   + 
Sbjct: 1575 PGPSSPYIPSPGGAMSPSYSP---TSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSP 1631

Query: 159  TMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS--LPTYDLGVMLPAIKTESGLSQTQSPLQ 216
            T   Y+  +       P+    YS T   YS   P+Y      P   + S  S + SP  
Sbjct: 1632 TSPNYSPTSPSYSPTSPS----YSPTSPSYSPTSPSYS-----PTSPSYSPTSPSYSPTS 1682

Query: 217  SGCLSYSPGFSTPQPGQTPYS--YQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYT 274
                  SP +S   P  +P S  Y     S++P+S  Y+  S S S          PSY+
Sbjct: 1683 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1742

Query: 275  AFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
                N     YS ++     TS + +  +PS + T
Sbjct: 1743 PTSPN-----YSPTSPNYTPTSPSYSPTSPSYSPT 1772



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 42/155 (27%), Positives = 58/155 (37%), Gaps = 15/155 (9%)

Query: 126  TSSGYSPRSAHQY--SPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQ 183
            TS  YSP S      SP   P+ P     S   + T  +Y+  +       P+    YS 
Sbjct: 1688 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS----YSP 1743

Query: 184  TGQPYS--LPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS--YQ 239
            T   YS   P Y      P   + S  S + SP        SP +S   P  +P S  Y 
Sbjct: 1744 TSPNYSPTSPNYT-----PTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYS 1798

Query: 240  MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYT 274
                S++PSS  Y   S + + +        PSY+
Sbjct: 1799 PTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYS 1833



 Score = 35.4 bits (80), Expect = 0.16
 Identities = 48/200 (24%), Positives = 70/200 (35%), Gaps = 21/200 (10%)

Query: 126  TSSGYSPRSAHQY--SPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQ 183
            TS  YSP S +    SP   P+ P     S   + T  +Y+  +     Q P  YT  S 
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPT-YTPSSP 1823

Query: 184  TGQPYSLPTYD--LGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYS---- 237
            +  P S P+Y        P   + S  S   +P        SP +S   P  +P S    
Sbjct: 1824 SYSPSS-PSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYS 1882

Query: 238  -----YQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGA 292
                 Y     +++P+S +Y   S   S          P Y+             STY  
Sbjct: 1883 PTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTY-- 1940

Query: 293  YMTSNNTADGTPSSTSTYQL 312
                + T+ G   ++ TY L
Sbjct: 1941 ----SPTSPGYSPTSPTYSL 1956


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 745 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 308 STYQLQES 315
            T    E+
Sbjct: 802 MTTVFTEN 809



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 710 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 762

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 763 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 797

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 798 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 898

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 899 EGSETTTAST 908



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 10/125 (8%)

Query: 11   SVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGG 70
            +V  T +E+  + +  S    +    S  T V    T GS     S   S + TT+  G 
Sbjct: 1125 TVSTTSSETTTASTTGSEMTTVFTTVSETTTVS---TIGSEATTSSAAGSEATTTSTEGS 1181

Query: 71   ENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGY 130
            E  T         + +T  S T       T     SETT  +  G+ +T T     S   
Sbjct: 1182 ETTTASTAGSETTTASTAGSET------TTASTAGSETTTASTSGS-ETNTACTTGSETS 1234

Query: 131  SPRSA 135
            +P SA
Sbjct: 1235 TPSSA 1239


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 745 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 308 STYQLQES 315
            T    E+
Sbjct: 802 MTTVFTEN 809



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 710 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 762

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 763 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 797

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 798 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 898

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 899 EGSETTTAST 908



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 745 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 308 STYQLQES 315
            T    E+
Sbjct: 802 MTTVFTEN 809



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 710 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 762

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 763 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 797

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 798 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 898

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 899 EGSETTTAST 908



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
           sapiens]
          Length = 1521

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 61/306 (19%), Positives = 112/306 (36%), Gaps = 11/306 (3%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSS 249
           + T   G    +I T S  ++  +      ++ + G        T        +  + ++
Sbjct: 685 VSTEGSGTTTVSI-TGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETT 743

Query: 250 TIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           T     S + S + +GS+    S T+      +   S +T  + + S  T   T SS  T
Sbjct: 744 TASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMT 803

Query: 310 YQLQES 315
               E+
Sbjct: 804 TVFTEN 809



 Score = 36.6 bits (83), Expect = 0.073
 Identities = 63/301 (20%), Positives = 116/301 (38%), Gaps = 34/301 (11%)

Query: 24   SQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSS-TSVTTNGTGGENMTVLNTADWL 82
            ++NS +      AS  T V    T GS  +  S   S T+ TT+  G E  T        
Sbjct: 807  TENSETTIASTTASETTTVS---TAGSETIPASTAGSETTTTTSTEGSETTTASTEGSET 863

Query: 83   LSCNTPSSATMSLLAVKTEPLNS----SETTATTGDGALDTFTGS--------VITSSGY 130
             + +T SS T +   + +E   +    SETT T+ +G+ +T T S        V T+   
Sbjct: 864  TTASTESSETTTATTIGSETTTASTEGSETTTTSTEGS-ETTTASTEGSEITTVSTTGSE 922

Query: 131  SPRSAHQYSPQLYPSKPYPHI--LSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPY 188
            +  ++ + S     S     +  +ST  ++T++  A  ++ + +      T  + T    
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSE 982

Query: 189  SLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPS 248
            +      G        E   + T S         S G  T     T     +  +  + +
Sbjct: 983  TTTVSTAGSETTTASIEGSETTTVS---------STGSETTTVSTTGTETTITSTEGSET 1033

Query: 249  STIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTS 308
            +T+    S + +   +GS+      T     + ++  + ST G+  T+ +TAD   ++ S
Sbjct: 1034 TTVTTAGSETTAVYTTGSE------TTTTSTEGSETTTVSTTGSETTTASTADLETTTVS 1087

Query: 309  T 309
            T
Sbjct: 1088 T 1088



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 745 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 308 STYQLQES 315
            T    E+
Sbjct: 802 MTTVFTEN 809



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 710 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 762

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 763 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 797

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 798 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 898

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 899 EGSETTTAST 908



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 745 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 308 STYQLQES 315
            T    E+
Sbjct: 802 MTTVFTEN 809



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 710 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 762

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 763 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 797

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 798 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 898

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 899 EGSETTTAST 908



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 745 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 308 STYQLQES 315
            T    E+
Sbjct: 802 MTTVFTEN 809



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 710 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 762

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 763 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 797

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 798 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 898

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 899 EGSETTTAST 908



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 10/125 (8%)

Query: 11   SVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGG 70
            +V  T +E+  + +  S    +    S  T V    T GS     S   S + TT+  G 
Sbjct: 1125 TVSTTSSETTTASTTGSEMTTVFTTVSETTTVS---TIGSEATTSSAAGSEATTTSTEGS 1181

Query: 71   ENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGY 130
            E  T         + +T  S T       T     SETT  +  G+ +T T     S   
Sbjct: 1182 ETTTASTAGSETTTASTAGSET------TTASTAGSETTTASTSGS-ETNTACTTGSETS 1234

Query: 131  SPRSA 135
            +P SA
Sbjct: 1235 TPSSA 1239


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 745 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 308 STYQLQES 315
            T    E+
Sbjct: 802 MTTVFTEN 809



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 710 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 762

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 763 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 797

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 798 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 898

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 899 EGSETTTAST 908



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091



 Score = 30.0 bits (66), Expect = 6.8
 Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 10/125 (8%)

Query: 11   SVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGG 70
            +V  T +E+  + +  S    +    S  T V    T GS     S   S + TT+  G 
Sbjct: 1125 TVSTTSSETTTASTTGSEMTTVFTTVSETTTVS---TIGSEATTSSAAGSEATTTSTEGS 1181

Query: 71   ENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGY 130
            E  T         + +T  S T       T     SETT  +  G+ +T T     S   
Sbjct: 1182 ETTTASTAGSETTTASTAGSET------TTASTAGSETTTASTSGS-ETNTACTTGSETS 1234

Query: 131  SPRSA 135
            +P SA
Sbjct: 1235 TPSSA 1239


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 69/311 (22%), Positives = 123/311 (39%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCNTPSSATMSLLA---VKTEP 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S T    A     T  
Sbjct: 49  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVS 108

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 109 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 157

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 158 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 212

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 213 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 268

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 269 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 326

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 327 FAAGSETIRAS 337



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 508 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 567

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 568 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 627

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 628 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 684

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 685 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 744

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 745 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 801

Query: 308 STYQLQES 315
            T    E+
Sbjct: 802 MTTVFTEN 809



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 650 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 709

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 710 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 762

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 763 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 797

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 798 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 842

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 843 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 898

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 899 EGSETTTAST 908



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 189 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 248

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 249 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 306

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 307 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 366

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 367 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 426

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 427 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 464



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 841  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 900

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 901  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 960

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 961  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1020

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1021 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1075

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1076 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1130

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1131 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1177

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1178 TEGSETTTASTAGSET 1193



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 748  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 807

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 808  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 862

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 863  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 922

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 923  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 981

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1037

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1038 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1091


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 70/321 (21%), Positives = 114/321 (35%), Gaps = 22/321 (6%)

Query: 22   SQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADW 81
            +Q+  +  +      +P     G  TP +  +  +   + + T   T    +T + T   
Sbjct: 1561 TQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTT 1620

Query: 82   LLSCNTPSSA-TMSLLAVKTEPLNSSETTATTGDGALDTFTGSV----ITSSGYSPRSAH 136
            + +  TP+   T +++ + T    +   T TTG     T T +     +T+S   P S+ 
Sbjct: 1621 VTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESS- 1679

Query: 137  QYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYS---QTGQPYSLPTY 193
              +PQ   S   P   ST    T+      T  +    P   T  S       P S  T 
Sbjct: 1680 --TPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTS 1737

Query: 194  DLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYA 253
              G   P   T +G S   +P      + S    TP P  TP   +  G    PSS +  
Sbjct: 1738 PPGT--PTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLIC 1795

Query: 254  NNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQ 313
               V N T ++  ++ Y     +G   Y  + + S        N +   TPS T T    
Sbjct: 1796 --CVLNDTYYAPGEEVYNG--TYGDTCY--FVNCSLSCTLEFYNWSCPSTPSPTPTPSKS 1849

Query: 314  ESLPGLTNQPGEFDTMQSPST 334
               P   ++P    +  +P T
Sbjct: 1850 TPTP---SKPSSTPSKPTPGT 1867



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 51/252 (20%), Positives = 83/252 (32%), Gaps = 16/252 (6%)

Query: 22   SQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADW 81
            +Q+  S  +      +P     G  TP  + +  +   + + T  GT     T + T   
Sbjct: 1515 TQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTT 1574

Query: 82   LLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQ 141
            +    TP+        + T     + T   T   +      +  T+   +P      +P 
Sbjct: 1575 VTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPT 1634

Query: 142  LYPSKPYPHILSTPAAQTMSA----------YAGQTQYSGMQQPAVYTAYSQTGQPYSLP 191
            + P      +  TP   T S            A  T  +   + +       T  P +  
Sbjct: 1635 MIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES 1694

Query: 192  TYDLGVMLPAIK---TESGLSQTQSPLQSG--CLSYSPGFSTPQPGQTPYSYQMPGSSFA 246
            T  L  + PAI+   T    + T     SG   LS  P  +T  PG TP      GSS A
Sbjct: 1695 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG-TPTRGTTTGSSSA 1753

Query: 247  PSSTIYANNSVS 258
            P+ +     + S
Sbjct: 1754 PTPSTVQTTTTS 1765



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 70/373 (18%), Positives = 121/373 (32%), Gaps = 42/373 (11%)

Query: 22   SQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADW 81
            +Q+  S  +      +P     G  TP ++ +  +   + + T  GT     T + T   
Sbjct: 1400 TQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTST 1459

Query: 82   LLSCNTPSSA--------TMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPR 133
            +    TP+          T +     T     ++T   T      T T +   +   +P 
Sbjct: 1460 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPT 1519

Query: 134  SAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQY---SGMQQPAVY-TAYSQTGQPYS 189
            S    +       P P    TP    +S     T     +G Q P       + T  P  
Sbjct: 1520 STPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1579

Query: 190  LPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSS 249
             PT         I T + ++ T +P  +   + +P  +T     TP        +  P S
Sbjct: 1580 TPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPIS 1639

Query: 250  TIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTS- 308
            T     +V+ +   +      P++T           S +      TSN   + +   TS 
Sbjct: 1640 T---TTTVTPTPTPTTGSTGPPTHT-----------STAPIAELTTSNPPPESSTPQTSR 1685

Query: 309  --TYQLQESLPGLTNQPG--EFDTMQSPSTP-----------IKDLDERTCRSSGSKSRG 353
              +  L ES   L+  P   E  +   PSTP           +      T    G+ +RG
Sbjct: 1686 STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRG 1745

Query: 354  RGRKNNPSPPPDS 366
                ++ +P P +
Sbjct: 1746 TTTGSSSAPTPST 1758



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 65/335 (19%), Positives = 107/335 (31%), Gaps = 29/335 (8%)

Query: 22   SQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADW 81
            +Q+  +  +      +P     G  TP S+ +  +   + + T  GT     T + T   
Sbjct: 1377 TQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1436

Query: 82   LLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQ 141
            +    TP+          T     + T   TG     T   +  T+   +P      +P 
Sbjct: 1437 VTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP- 1495

Query: 142  LYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPA 201
                        TP A T +     T      Q    T  + T      PT   G   P 
Sbjct: 1496 ------------TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT-PTGTQTPT 1542

Query: 202  ---IKTESGLSQTQSPLQSGCLSYSP--GFSTPQPGQTPYSYQMPGSSFAPSSTIYANNS 256
               I T + ++ T +P  +   + +P    +T  P  TP   Q P +    ++T      
Sbjct: 1543 PTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTP 1602

Query: 257  VSNST--------NFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTS 308
               ST          + +    P+ T           + +T     T    + G P+ TS
Sbjct: 1603 TPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTS 1662

Query: 309  TYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERT 343
            T  + E     +N P E  T Q+  +    L E T
Sbjct: 1663 TAPIAELT--TSNPPPESSTPQTSRSTSSPLTEST 1695


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 69/311 (22%), Positives = 126/311 (40%), Gaps = 32/311 (10%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGT-GGENMTVLNTADWLLSCN-TPSSATMSLLAVKTE--P 102
           +P  S+    ++S + +TT  T G EN TV +      + +   S +T+S    +T    
Sbjct: 70  SPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTTVS 129

Query: 103 LNSSETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSA 162
           +  +ETT  +  G+ +T T S  +S      +A   +            +ST  ++T +A
Sbjct: 130 ITGTETTMVSAMGS-ETTTNSTTSSETTVTSTAGSETT----------TVSTVGSETTTA 178

Query: 163 YAGQTQ-----YSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQS 217
           Y   ++      +G +   V+TA S+T  P +      G     + T    + T S   S
Sbjct: 179 YTADSETTAASTTGSEMTTVFTAGSETITPST-----AGSETTTVSTAGSETTTVSTTGS 233

Query: 218 GCLSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFG 277
              + S   S      T  S     S+    +T+    S + S   + S +D  + TAF 
Sbjct: 234 ETTTASTAHSETTAASTMGSETTKVSTAGSETTV----STAGSETTAASTEDSETNTAFT 289

Query: 278 QNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPG-LTNQPGEFDTMQSPSTPI 336
           ++  ++  +AST G   T+ +T    P+  ST   + ++   +  +  +  T  S  T +
Sbjct: 290 ED--SKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPETTKVSTASSEVTTV 347

Query: 337 KDLDERTCRSS 347
                 T R+S
Sbjct: 348 FAAGSETIRAS 358



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 65/308 (21%), Positives = 112/308 (36%), Gaps = 15/308 (4%)

Query: 17  TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTGGENMTVL 76
           TE   + + ++   EM  +++  +      T GS     S     + TT+  G E  TV 
Sbjct: 529 TEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVS 588

Query: 77  NTADWLLSCNTPSSATMSLLAVKTE-----PLNSSETTATTGDGALD--TFTGSVITSSG 129
            T     + +T  S T +     +E       +S  TTA+T D      + TGS  T++ 
Sbjct: 589 TTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTAS 648

Query: 130 YSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYS 189
            +       S +         + +T +  TM +  G  +     + +  T  S TG   +
Sbjct: 649 TTSSETTTASTE---GSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETT 705

Query: 190 LPTYDLGVMLPAI--KTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQMPGSSFAP 247
           + T   G    +I     + +S T S   +     S   +    G    +    GS    
Sbjct: 706 VSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTT 765

Query: 248 SSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSST 307
           +ST     S + S + +GS+    S T+      +   S +T  + + S  T   T SS 
Sbjct: 766 AST---EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSK 822

Query: 308 STYQLQES 315
            T    E+
Sbjct: 823 MTTVFTEN 830



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 67/310 (21%), Positives = 106/310 (34%), Gaps = 57/310 (18%)

Query: 6   DLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLV--GGGDTP----GSSKLEKSNLS 59
           D     V  T +E  ++ ++ S +  +    S  T+   G G T     GS   + S   
Sbjct: 671 DSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTG 730

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALDT 119
           S + TT+  G E  T   T     + +T  S T       T     SETT+ +  G+ +T
Sbjct: 731 SETTTTSTEGSEITTASITGSETTTASTEGSET------TTASTEGSETTSASTTGS-ET 783

Query: 120 FTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVYT 179
            T S  +S                          T  A  M +        G +   V T
Sbjct: 784 TTASTTSS-------------------------ETTMASIMGSETTMASTIGSETTKVST 818

Query: 180 AYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSYQ 239
           A S+               +  + TE+  +   S   S   + S   S   P  T  S  
Sbjct: 819 ASSK---------------MTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSET 863

Query: 240 MPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNNT 299
              +S   S T  A+   S +T  S    +  + T  G    ++  +AST G+  T+ +T
Sbjct: 864 TTTTSTEGSETTTASTEGSETTTASTESSETTTATTIG----SETTTASTEGSETTTTST 919

Query: 300 ADGTPSSTST 309
                ++ ST
Sbjct: 920 EGSETTTAST 929



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 51/255 (20%), Positives = 102/255 (40%), Gaps = 24/255 (9%)

Query: 60  STSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTE----PLNSSETTATTGDG 115
           S + T + TG E  T+L  A    + +T  S T +     ++     ++ SE T T+  G
Sbjct: 34  SNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAG 93

Query: 116 ALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQP 175
           + +T     ++S+G    +A     +          +ST  ++T +     T+ + +   
Sbjct: 94  SENT----TVSSAGSGTTTASMAGSE--------STISTAGSETTTVSITGTETTMVSAM 141

Query: 176 AVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTP 235
              T  + T    +  T   G     + T    + T     S   + S   S      T 
Sbjct: 142 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 201

Query: 236 YSYQM-PGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYM 294
            S  + P ++ + ++T+    S + + + +GS+      T      +++  +AST G+  
Sbjct: 202 GSETITPSTAGSETTTVSTAGSETTTVSTTGSE------TTTASTAHSETTAASTMGSET 255

Query: 295 TSNNTADGTPSSTST 309
           T  +TA G+ ++ ST
Sbjct: 256 TKVSTA-GSETTVST 269



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 52/278 (18%), Positives = 98/278 (35%), Gaps = 17/278 (6%)

Query: 47  TPGSSKLEKSNLSSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSS 106
           T GS     S   S + T + TG E  T         + +T  S T  +    +E   S+
Sbjct: 210 TAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVST 269

Query: 107 ETTATTGDGALDTFTGSVIT---------SSGYSPRSAHQYSPQLYPSKPYPHILSTPAA 157
             + TT     D+ T +  T         ++G+   +A     +  P+        T  A
Sbjct: 270 AGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSE--PTMASTMGSETTMA 327

Query: 158 QTMSAYAGQTQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGL---SQTQSP 214
            T+     +   +  +   V+ A S+T +  ++ +    V     +T +     S+T + 
Sbjct: 328 STIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTD 387

Query: 215 LQSGC---LSYSPGFSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYP 271
             +G     + + G  T              ++ + ++T+   +S + +T   GS+    
Sbjct: 388 STTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAV 447

Query: 272 SYTAFGQNQYAQYYSASTYGAYMTSNNTADGTPSSTST 309
           S T F     +   S  T  +   S  T   T  S +T
Sbjct: 448 STTVFETTTASTEGSEITIASTSDSETTTASTEGSETT 485



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 75/376 (19%), Positives = 131/376 (34%), Gaps = 57/376 (15%)

Query: 10   QSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSSTSVTTNGTG 69
            ++   T TE   + + ++   E    ++  +      T GS     S   S + TT+  G
Sbjct: 862  ETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEG 921

Query: 70   GENMTVLNTADWLLSCNTPSSATMS-----------------LLAVKTE-------PLNS 105
             E  T       + + +T  S T +                 L  V T            
Sbjct: 922  SETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEG 981

Query: 106  SETTATTGDGALDTFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAG 165
            SETT  T  G+  T   +  + +     +  + +           + ST +  T  +  G
Sbjct: 982  SETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG 1041

Query: 166  Q----TQYSGMQQPAVYTAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLS 221
                 T   G +   V TA S+T        Y  G       TE   + T S   S   +
Sbjct: 1042 TETTITSTEGSETTTVTTAGSET-----TAVYTTGSETTTTSTEGSETTTVSTTGSETTT 1096

Query: 222  YSPG------FSTPQPGQTPYSYQMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTA 275
             S         ST   G T  S     ++ + ++T+Y   S + + +  GS+    S T+
Sbjct: 1097 ASTADLETTTVSTSGSGTTTAS-----TAGSETTTVYITGSKTTTASTEGSEATTVSTTS 1151

Query: 276  FGQNQYAQYYSASTYGAYMTSNNTADGTPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTP 335
                  ++  +AST G+ MT   T   T S T+T     S    ++  G     ++ +T 
Sbjct: 1152 ------SETTTASTTGSEMT---TVFTTVSETTTVSTIGSEATTSSAAGS----EATTTS 1198

Query: 336  IKDLDERTCRSSGSKS 351
             +  +  T  ++GS++
Sbjct: 1199 TEGSETTTASTAGSET 1214



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 74/358 (20%), Positives = 128/358 (35%), Gaps = 24/358 (6%)

Query: 2    EDSQDLNEQSVKKTCTESDVSQSQNSRSMEMQDLASPHTLVGGGDTP---GSSKLEKSNL 58
            E S+  +  +     T +  + S+ + +  M    +  + +G   T     SSK+     
Sbjct: 769  EGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFT 828

Query: 59   SSTSVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTEPLNSSETTATTGDGALD 118
             ++  T   T     T ++TA    S   P+S   S     T    S  TTA+T +G+ +
Sbjct: 829  ENSETTIASTTASETTTVSTAG---SETIPASTAGSETTTTTSTEGSETTTAST-EGS-E 883

Query: 119  TFTGSVITSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSGMQQPAVY 178
            T T S  +S   +  +    +             ST  ++T +A    ++ + +      
Sbjct: 884  TTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSE 943

Query: 179  TAYSQTGQPYSLPTYDLGVMLPAIKTESGLSQTQSPLQSGCLSYSPGFSTPQPGQTPYSY 238
            T  + T    +      G  L  + T    + T S   S   + +   S      T  S 
Sbjct: 944  TTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS- 1002

Query: 239  QMPGSSFAPSSTIYANNSVSNSTNFSGSQQDYPSYTAFGQNQYAQYYSASTYGAYMTSNN 298
            +    S A S T  A+   S +T  S +  +  + +  G     +    ST G+  T+  
Sbjct: 1003 ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTG----TETTITSTEGSETTTVT 1058

Query: 299  TADG-------TPSSTSTYQLQESLPGLTNQPGEFDTMQSPSTPIKDLDERTCRSSGS 349
            TA         T S T+T   + S     +  G   T  S +    DL+  T  +SGS
Sbjct: 1059 TAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTA----DLETTTVSTSGS 1112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,755,437
Number of Sequences: 37866
Number of extensions: 1249629
Number of successful extensions: 4293
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 168
Number of HSP's that attempted gapping in prelim test: 3678
Number of HSP's gapped (non-prelim): 620
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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