BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|98986457 host cell factor 1 [Homo sapiens] (2035 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|98986457 host cell factor 1 [Homo sapiens] 4024 0.0 gi|7019405 host cell factor C2 [Homo sapiens] 594 e-169 gi|116284392 mucin 2 precursor [Homo sapiens] 217 8e-56 gi|91982772 mucin 17 [Homo sapiens] 189 2e-47 gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 164 6e-40 gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 161 5e-39 gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 161 5e-39 gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 161 5e-39 gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 161 7e-39 gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 161 7e-39 gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 161 7e-39 gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 161 7e-39 gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 160 2e-38 gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 160 2e-38 gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 160 2e-38 gi|161019170 mucin 5AC [Homo sapiens] 149 3e-35 gi|167736355 mucin 4 isoform a [Homo sapiens] 140 1e-32 gi|83367077 mucin 16 [Homo sapiens] 138 6e-32 gi|151301154 mucin 6, gastric [Homo sapiens] 132 4e-30 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 129 4e-29 gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap... 126 2e-28 gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 119 4e-26 gi|163965366 nascent polypeptide-associated complex alpha subuni... 118 5e-26 gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 118 7e-26 gi|16945972 kelch domain containing 3 [Homo sapiens] 114 1e-24 gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 112 4e-24 gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 106 3e-22 gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens] 102 4e-21 gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens] 96 4e-19 gi|7657301 kelch domain containing 2 [Homo sapiens] 89 6e-17 >gi|98986457 host cell factor 1 [Homo sapiens] Length = 2035 Score = 4024 bits (10437), Expect = 0.0 Identities = 2035/2035 (100%), Positives = 2035/2035 (100%) Query: 1 MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELH 60 MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELH Sbjct: 1 MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELH 60 Query: 61 VYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEW 120 VYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEW Sbjct: 61 VYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEW 120 Query: 121 KRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRP 180 KRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRP Sbjct: 121 KRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRP 180 Query: 181 GSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTL 240 GSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTL Sbjct: 181 GSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTL 240 Query: 241 TWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLN 300 TWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLN Sbjct: 241 TWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLN 300 Query: 301 LDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLE 360 LDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLE Sbjct: 301 LDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLE 360 Query: 361 TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV 420 TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV Sbjct: 361 TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV 420 Query: 421 PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAART 480 PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAART Sbjct: 421 PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAART 480 Query: 481 QGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS 540 QGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS Sbjct: 481 QGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS 540 Query: 541 PQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPV 600 PQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPV Sbjct: 541 PQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPV 600 Query: 601 MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT 660 MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT Sbjct: 601 MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT 660 Query: 661 ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720 ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT Sbjct: 661 ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720 Query: 721 ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780 ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ Sbjct: 721 ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780 Query: 781 AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG 840 AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG Sbjct: 781 AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG 840 Query: 841 QPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH 900 QPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH Sbjct: 841 QPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH 900 Query: 901 STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960 STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV Sbjct: 901 STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960 Query: 961 TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET 1020 TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET Sbjct: 961 TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET 1020 Query: 1021 HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC 1080 HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC Sbjct: 1021 HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC 1080 Query: 1081 ETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACA 1140 ETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACA Sbjct: 1081 ETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACA 1140 Query: 1141 AGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE 1200 AGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE Sbjct: 1141 AGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE 1200 Query: 1201 PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCES 1260 PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCES Sbjct: 1201 PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCES 1260 Query: 1261 LQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNP 1320 LQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNP Sbjct: 1261 LQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNP 1320 Query: 1321 PCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDA 1380 PCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDA Sbjct: 1321 PCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDA 1380 Query: 1381 TSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNM 1440 TSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNM Sbjct: 1381 TSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNM 1440 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP Sbjct: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQE 1560 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQE Sbjct: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQE 1560 Query: 1561 SAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA 1620 SAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA Sbjct: 1561 SAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA 1620 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT Sbjct: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 Query: 1681 TIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTV 1740 TIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTV Sbjct: 1681 TIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTV 1740 Query: 1741 PSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPP 1800 PSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPP Sbjct: 1741 PSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPP 1800 Query: 1801 PSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGT 1860 PSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGT Sbjct: 1801 PSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGT 1860 Query: 1861 AYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKI 1920 AYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKI Sbjct: 1861 AYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKI 1920 Query: 1921 IEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII 1980 IEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII Sbjct: 1921 IEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII 1980 Query: 1981 FRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSAPKKSKADGQ 2035 FRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSAPKKSKADGQ Sbjct: 1981 FRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSAPKKSKADGQ 2035 >gi|7019405 host cell factor C2 [Homo sapiens] Length = 792 Score = 594 bits (1531), Expect = e-169 Identities = 301/581 (51%), Positives = 382/581 (65%), Gaps = 31/581 (5%) Query: 19 WKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDI 78 W+RV ++GPVPR RHGHRAVAI+EL+++FGGGNEGI DELHVYNTATNQWF+PAVRGDI Sbjct: 9 WRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWFLPAVRGDI 68 Query: 79 PPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRL 138 PPGCAA+GFVCDGTR+LVFGGMVEYG+YSN+LYELQASRW WK++K P +G PPCPRL Sbjct: 69 PPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPCPRL 128 Query: 139 GHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPP 198 GHSFSL GNKCYLFGGLAN+SED NN+PRYLND Y LEL+ GSGVV W IP+T GV+P Sbjct: 129 GHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPS 188 Query: 199 PRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTLTWNKPSLSGVAPLPRSLH 258 PRESHTAV+Y +KD+ K+ ++GGM G RL DLW LD++T++W+KP G PLPRSLH Sbjct: 189 PRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLH 248 Query: 259 SATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLED-- 316 +A+ IGNKMY+FGGWVP ++ + + H+ EW+CT++ + LNLDT W T++ D+ ED Sbjct: 249 TASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLVSDSQEDKK 308 Query: 317 -NIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRA 375 + PR RAGHCAVAI TRLY WSGRDGY+KA N+QVCCKDLWYL+TEKPP P++VQL++A Sbjct: 309 NSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKA 368 Query: 376 NTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAP 435 TNS V W V+T + YLLQL D+P AA++ S S AP Sbjct: 369 TTNSFHVKWDEVSTVEGYLLQLST-DLPYQAASSDS---------------SAAPNMQGV 412 Query: 436 AVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVL--KVTGPQ 493 + P Q ++P + +T + T S + P A+L + Sbjct: 413 RMDPHRQGSNNIVPNSINDTINSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNA 472 Query: 494 ATTGTPLVTMRPASQA--GKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAA 551 + + +V M ++ A V V S VR V+P S TV S+ M + Sbjct: 473 SNHNSHVVDMLRKNEGPHTSANVGVLSSCLDVRTVIPETSVSSTV-SSTQTMVTQQTIKT 531 Query: 552 AAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPAT 592 +++T V+ T T + T LPAT Sbjct: 532 ESSSTN-------GAVVKDETSLTTFSTKSEVDETYALPAT 565 Score = 244 bits (624), Expect = 5e-64 Identities = 128/281 (45%), Positives = 173/281 (61%), Gaps = 17/281 (6%) Query: 1736 LAGTVPSTVALLPSTA--TESLAPSNTFVAPQPVVVASPAKLQA-------AATLTEVAN 1786 ++ TV ST ++ TES + + V + + K + A ++ V Sbjct: 513 VSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVET 572 Query: 1787 GIESLGVKPDLPPPPSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGT-- 1844 + + P P E QW DVG+ K +V+ ++L P S +G Sbjct: 573 HATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGK-QSISKVGNAD 631 Query: 1845 VPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPD 1904 VPDY+ LKKQ+L PGT Y+FRVA IN CG GPFS+IS FKTC+PGFPGAP A++ISK+ + Sbjct: 632 VPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVE 691 Query: 1905 GAHLTWEPPSVTSGKIIEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSS 1964 G HL+WEPP+ SG I+EYS YLAI+++Q P+QL FMR+YCG SC+V + Sbjct: 692 GIHLSWEPPTSPSGNILEYSAYLAIRTAQI-----QDNPSQLVFMRIYCGLKTSCIVTAG 746 Query: 1965 SLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSK 2005 L+NAHIDYT++PAI+FRI+A+NEKGYGPATQVRWLQ +K Sbjct: 747 QLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNK 787 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 217 bits (553), Expect = 8e-56 Identities = 307/1287 (23%), Positives = 418/1287 (32%), Gaps = 165/1287 (12%) Query: 403 PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455 P T T +PTP P + P + P Q T IT P P Sbjct: 2751 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2810 Query: 456 ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 P TTT V PT + PT T + VT TGT T P Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 2867 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565 + VT T P G + T T + +P +G T + P+ P Sbjct: 2868 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2925 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T P T I T VTP T T T ++P+ + T Q T+ T Sbjct: 2926 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 T+ P T + T T + TT T T T ++P + P + + Sbjct: 2985 TTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3030 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAG 745 P T T +T P+T T P P T + T+ TT +T T Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089 Query: 746 TKPT---ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801 PT I ++V+P+ T GT T T I + +T T +P +PIT TT Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3148 Query: 802 KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGT-ILR 847 T + T P T V T G Q T + P GT Sbjct: 3149 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3208 Query: 848 TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907 T P+ VTP TT + TT VT T TGT + T+ + Sbjct: 3209 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPIT 3259 Query: 908 TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967 T T T +Q T IT + T G TPT T P++ T VT P+ Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3317 Query: 968 GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027 G + + + + TT PT T T + T T+ + P T TT Sbjct: 3318 GTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372 Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSN------- 1077 TTT V P PT Q + VT T G Q + + + Sbjct: 3373 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3429 Query: 1078 PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137 P T TT TT T + P T T TT T T + G Sbjct: 3430 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3481 Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197 TP I+ T + + QT T+ +TT TV T P Sbjct: 3482 -----TPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP----------- 3523 Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 G ++P + ++ +P+ P +T T + G P P+ Sbjct: 3524 ---TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310 +TT TVT P+ T TQ + P T T T T T TT+ Sbjct: 3581 ---------TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626 Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370 + V P +T TT TT T+ T P G Q P T T T T Sbjct: 3627 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3686 Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430 P T++ T P+ TP T + P PT P T TT Sbjct: 3687 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3746 Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------L 1480 T T T T + P + + G T+ TTTV+ T Sbjct: 3747 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3806 Query: 1481 TRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGE 1530 T +TT T TP P P + P V+P P Q P + + +T Sbjct: 3807 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3866 Query: 1531 SAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVD 1583 + T + ++ T P+ Q + + T V P P PT + + Sbjct: 3867 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3926 Query: 1584 QLS--LPQELMAEAQAGTTTLMVTGLT 1608 + P Q TTT + T T Sbjct: 3927 TTTTVTPTPTPTGTQTPTTTPITTTTT 3953 Score = 217 bits (553), Expect = 8e-56 Identities = 308/1287 (23%), Positives = 418/1287 (32%), Gaps = 165/1287 (12%) Query: 403 PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455 P T T +PTP P + P + P Q T IT P P Sbjct: 2912 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2971 Query: 456 ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 P TTT V PT + PT T + VT TGT T P Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3028 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565 + VT T P G + T T + +P +G T + P+ P Sbjct: 3029 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3086 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T P T I T VTP T T T ++P+ + T Q T+ T Sbjct: 3087 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 T+ P T + T T + TT T T T ++P + P + + Sbjct: 3146 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3191 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744 P T T +T P+T T P P GT T TT+ T +G Sbjct: 3192 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 3250 Query: 745 GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801 T T I ++V+P+ T GT T T I + +T T +P +PIT TT Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3309 Query: 802 KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGTIL-R 847 T + T P T V T G Q T + P GT Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369 Query: 848 TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907 T P+ VTP TT + TT VT T TGT + T+ + Sbjct: 3370 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------TTTPIT 3420 Query: 908 TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967 T T T +Q T IT + T G TPT T P++ T VT P+ Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3478 Query: 968 GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027 G + + + + TT PT T T + T T+ + P T TT Sbjct: 3479 GTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533 Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSNP------ 1078 TTT V P PT Q + VT T G Q + + + Sbjct: 3534 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590 Query: 1079 -PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137 P T TT TT T + P T T TT T T + G Sbjct: 3591 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3642 Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197 TP I+ T + +Q T T+ +TT TV T P Sbjct: 3643 -----TPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT---------- 3685 Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 G ++P + ++ +P+ P +T T + G P P+ Sbjct: 3686 ----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310 +TT TVT P+ T TQ + P T T T T T TT+ Sbjct: 3742 ---------TTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787 Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370 + V P +T TT TT T+ T P G Q P T T T T Sbjct: 3788 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3847 Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430 P T++ T P+ TP T + P PT P T TT Sbjct: 3848 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3907 Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------L 1480 T T T T + P + + G T+ TTTV+ T Sbjct: 3908 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3967 Query: 1481 TRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGE 1530 T +TT T TP P P + P V+P P Q P + + +T Sbjct: 3968 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4027 Query: 1531 SAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVD 1583 + T + ++ T P+ Q + + T V P P PT + + Sbjct: 4028 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4087 Query: 1584 QLS--LPQELMAEAQAGTTTLMVTGLT 1608 + P Q TTT + T T Sbjct: 4088 TTTTVTPTPTPTGTQTPTTTPITTTTT 4114 Score = 217 bits (552), Expect = 1e-55 Identities = 304/1283 (23%), Positives = 421/1283 (32%), Gaps = 153/1283 (11%) Query: 403 PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455 P T T +PTP P + P + P Q T IT P P Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3132 Query: 456 ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 P TTT V PT + PT T + VT TGT T P Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3189 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565 + VT T P G + T T + +P +G T + P+ P Sbjct: 3190 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3247 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T P T I T VTP T T T ++P+ + T Q T+ T Sbjct: 3248 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 T+ P T + T T + TT T T T ++P + P + + Sbjct: 3307 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3352 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744 P T T +T P+T T P P GT T TT+ T +G Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 3411 Query: 745 GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801 T T I ++V+P+ T GT T T I + +T T +P +PIT TT Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3470 Query: 802 KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGTIL-R 847 T + T P T V T G Q T + P GT Sbjct: 3471 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3530 Query: 848 TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907 T P+ VTP TT + TT VT T TGT + T+ + Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------TTTPIT 3581 Query: 908 TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967 T T T +Q T IT + T G TPT T P++ T VT P+ Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3639 Query: 968 GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027 G + + + + TT PT T T + T T+ + P T TT Sbjct: 3640 GTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694 Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSNP------ 1078 TTT V P PT Q + VT T G Q + + + Sbjct: 3695 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3751 Query: 1079 -PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137 P T TT TT T + P T T TT T T + G Sbjct: 3752 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3803 Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197 TP I+ T + +Q T T+ +TT TV T P Sbjct: 3804 -----TPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT---------- 3846 Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 G ++P + ++ +P+ P +T T + G P P+ Sbjct: 3847 ----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310 +TT TVT P+ T TQ + P T T T T T TT+ Sbjct: 3903 ---------TTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948 Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370 + V P +T TT TT T+ T P G Q P T T T T Sbjct: 3949 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4008 Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430 P T++ T P+ TP T + P PT P T TT Sbjct: 4009 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068 Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQ 1489 T T T T + P + + G T+ TTTV+ T T T Sbjct: 4069 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4128 Query: 1490 STPVPGPSVPPPEELQVSPGPR-QQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVD 1548 +TP+ + P +P P Q P + + +T + T + Sbjct: 4129 TTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4183 Query: 1549 LSSTGEPSSGQES----AGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMV 1604 ++ T P+ Q +A +A + PPP + S PQ + + T + + Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPP------ESSTPQTSRSTSSPLTESTTL 4237 Query: 1605 TGLTPEELAVTAAAEAAAQAAAT 1627 P + +T+ A + A T Sbjct: 4238 LSTLPPAIEMTSTAPPSTPTAPT 4260 Score = 215 bits (548), Expect = 3e-55 Identities = 304/1272 (23%), Positives = 415/1272 (32%), Gaps = 154/1272 (12%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 P T T+ T P P+ + P V P T P P TTTT+ Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVT 2644 Query: 463 VLPTVPGSSISVPT-AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521 PT G+ T T V TG Q T TP+ T VT T P Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--------TTTVTPTPTPT 2696 Query: 522 GVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580 G + T T + +P +G T + P+ PT P T I T Sbjct: 2697 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756 Query: 581 AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGT 640 VTP T T T ++P+ + T Q T+ T T+ P T + T Sbjct: 2757 TVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2815 Query: 641 VTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ 700 T + TT T T T ++P + P + + P T T Sbjct: 2816 PTT---TPITTTTTVTPTPTPTGTQTPTTTP-----------ITTTTTVTPTPTPTGTQT 2861 Query: 701 ASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPT---ILGISSVS 757 +T P+T T P P T + T+ TT +T T PT I ++V+ Sbjct: 2862 PTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2920 Query: 758 PSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITTKVMT-------SGTG 809 P+ T GT T T I + +T T +P +PIT TT T + T Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTT 2979 Query: 810 APAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGT-ILRTVPMGGVRLVTPVTV 862 P T V T G Q T + P GT T P+ VTP Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039 Query: 863 SAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQ 922 TT + TT VT T TGT + T+ + T T T +Q Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTPTPTGTQ 3090 Query: 923 VINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSIL 982 T IT + T G TPT T P++ T VT P+G + + + Sbjct: 3091 TPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTP-----TTTPI 3143 Query: 983 ASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQ 1042 + TT PT T T + T T+ + P T TT TTT V P Sbjct: 3144 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PT 3200 Query: 1043 PTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSN-------PPCETHETGTTNTAT 1092 PT Q + VT T G Q + + + P T TT T Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260 Query: 1093 TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVA 1152 T T + P T T TT T T + G TP I+ Sbjct: 3261 TTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------------TPTTTPITTT 3307 Query: 1153 TGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLA 1212 T + + QT T+ +TT TV T P G ++P + Sbjct: 3308 TTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP--------------TGTQTPTTTPIT 3351 Query: 1213 PLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTV 1272 ++ +P+ P +T T + G P P+ +TT TV Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI---------TTTTTV 3402 Query: 1273 TALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNAGSAQRVCSNPPCETH 1325 T P+ T TQ + P T T T T T TT+ + V P Sbjct: 3403 TP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457 Query: 1326 ETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHR 1385 +T TT TT T+ T P G Q P T T T T P T++ Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517 Query: 1386 TVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT-TVTSNMSSNQ 1444 T P+ TP T + P PT P T TT T T T T + Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------LTRAVTTVTQSTPVPG 1495 P + + G T+ TTTV+ T T +TT T TP P Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637 Query: 1496 P-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGESAEVLSASQTPELPA 1545 P + P V+P P Q P + + +T + T + Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697 Query: 1546 AVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVDQLS--LPQELMAEAQ 1596 ++ T P+ Q + + T V P P PT + + + P Q Sbjct: 3698 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3757 Query: 1597 AGTTTLMVTGLT 1608 TTT + T T Sbjct: 3758 TPTTTPITTTTT 3769 Score = 214 bits (545), Expect = 7e-55 Identities = 305/1279 (23%), Positives = 418/1279 (32%), Gaps = 158/1279 (12%) Query: 403 PATAATAT-SPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAP-------A 454 P T T +PT P+ + P P P+T T+ P P Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTT 2611 Query: 455 PPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPV 514 P TTT V PT + PT T + VT TGT T P + V Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTV 2666 Query: 515 TVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTVLSVPAG 573 T T P G + T T + +P +G T + P+ PT P Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726 Query: 574 TTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPII 633 T I T VTP T T T ++P+ + T Q T+ T T+ P Sbjct: 2727 TPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2785 Query: 634 TVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQ 693 T + T T + TT T T T ++P + P + + P Sbjct: 2786 TPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP-----------ITTTTTVTPTP 2831 Query: 694 TSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPT---I 750 T T +T P+T T P P T + T+ TT +T T PT I Sbjct: 2832 TPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890 Query: 751 LGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITTKVMT---- 805 ++V+P+ T GT T T I + +T T +P +PIT TT T Sbjct: 2891 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPT 2949 Query: 806 ---SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGT-ILRTVPMGGVR 855 + T P T V T G Q T + P GT T P+ Sbjct: 2950 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3009 Query: 856 LVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGT 915 VTP TT + TT VT T TGT + T+ + T T T Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPT 3060 Query: 916 IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVH 975 +Q T IT + T G TPT T P++ T VT P+G + Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTP--- 3115 Query: 976 DLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVA 1035 + + + TT PT T T + T T+ + P T TT TTT V Sbjct: 3116 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3173 Query: 1036 NLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSN-------PPCETHET 1085 P PT Q + VT T G Q + + + P T Sbjct: 3174 PT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230 Query: 1086 GTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPA 1145 TT TT T + P T T TT T T + G TP Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------------TPT 3277 Query: 1146 VIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRS 1205 I+ T + + QT T+ +TT TV T P G ++ Sbjct: 3278 TTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP--------------TGTQT 3321 Query: 1206 PAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGS 1265 P + ++ +P+ P +T T + G P P+ Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-------- 3373 Query: 1266 PSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNAGSAQRVCS 1318 +TT TVT P+ T TQ + P T T T T T TT+ + V Sbjct: 3374 -TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427 Query: 1319 NPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLP 1378 P +T TT TT T+ T P G Q P T T T T P Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487 Query: 1379 DATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT-TVT 1437 T++ T P+ TP T + P PT P T TT T T T T Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3547 Query: 1438 SNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------LTRAVTTVT 1488 + P + + G T+ TTTV+ T T +TT T Sbjct: 3548 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3607 Query: 1489 QSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGESAEVLSAS 1538 TP P P + P V+P P Q P + + +T + Sbjct: 3608 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3667 Query: 1539 QTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVDQLS--LPQ 1589 T + ++ T P+ Q + + T V P P PT + + + P Sbjct: 3668 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3727 Query: 1590 ELMAEAQAGTTTLMVTGLT 1608 Q TTT + T T Sbjct: 3728 PTPTGTQTPTTTPITTTTT 3746 Score = 213 bits (543), Expect = 1e-54 Identities = 289/1203 (24%), Positives = 399/1203 (33%), Gaps = 149/1203 (12%) Query: 403 PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455 P T T +PTP P + P + P Q T IT P P Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3270 Query: 456 ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 P TTT V PT + PT T + VT TGT T P Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3327 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565 + VT T P G + T T + +P +G T + P+ P Sbjct: 3328 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3385 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T P T I T VTP T T T ++P+ + T Q T+ T Sbjct: 3386 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 T+ P T + T T + TT T T T ++P + P + + Sbjct: 3445 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3490 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744 P T T +T P+T T P P GT T TT+ T +G Sbjct: 3491 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 3549 Query: 745 GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801 T T I ++V+P+ T GT T T I + +T T +P +PIT TT Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3608 Query: 802 KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGTIL-R 847 T + T P T V T G Q T + P GT Sbjct: 3609 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3668 Query: 848 TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907 T P+ VTP TT + TT VT T TGT + T+ + Sbjct: 3669 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------TTTPIT 3719 Query: 908 TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967 T T T +Q T IT + T G TPT T P++ T VT P+ Sbjct: 3720 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3777 Query: 968 GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027 G + + + + TT PT T T + T T+ + P T TT Sbjct: 3778 GTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832 Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSNP------ 1078 TTT V P PT Q + VT T G Q + + + Sbjct: 3833 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889 Query: 1079 -PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137 P T TT TT T + P T T TT T T + G Sbjct: 3890 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3941 Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197 TP I+ T + +Q T T+ +TT TV T P Sbjct: 3942 -----TPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT---------- 3984 Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 G ++P + ++ +P+ P +T T + G P P+ Sbjct: 3985 ----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310 +TT TVT P+ T TQ + P T T T T T TT+ Sbjct: 4041 ---------TTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4086 Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370 + V P +T TT TT T+ T P G Q P T T T T Sbjct: 4087 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4146 Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430 P T++ T P+ TP T + P PT P T T Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQTGPPT 4199 Query: 1431 HTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQS 1490 HT+T + ++++ PP +++ Q ++ + + T S + + T T +T T Sbjct: 4200 HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAP 4259 Query: 1491 TPVPGPSV--PPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVD 1548 T G PPP PG P R +S+A + + + S P + Sbjct: 4260 TTTSGGHTLSPPPSTTTSPPG----TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS 4315 Query: 1549 LSS 1551 S Sbjct: 4316 TPS 4318 Score = 213 bits (541), Expect = 2e-54 Identities = 307/1253 (24%), Positives = 412/1253 (32%), Gaps = 176/1253 (14%) Query: 403 PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455 P T T +PTP P + P + P Q T IT P P Sbjct: 3142 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3201 Query: 456 ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 P TTT V PT + PT T + VT TGT T P Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3258 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565 + VT T P G + T T + +P +G T + P+ P Sbjct: 3259 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3316 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T P T I T VTP T T T ++P+ + T Q T+ T Sbjct: 3317 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 T+ P T + T T + TT T T T ++P + P + + Sbjct: 3376 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3421 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744 P T T +T P+T T P P GT T TT+ T +G Sbjct: 3422 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 3480 Query: 745 GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801 T T I ++V+P+ T GT T T I + +T T +P +PIT TT Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3539 Query: 802 KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGTIL-R 847 T + T P T V T G Q T + P GT Sbjct: 3540 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3599 Query: 848 TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907 T P+ VTP TT + TT VT T TGT + T+ + Sbjct: 3600 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------TTTPIT 3650 Query: 908 TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967 T T T +Q T IT + T G TPT T P++ T VT P+ Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3708 Query: 968 GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027 G + + + + TT PT T T + T T+ + P T TT Sbjct: 3709 GTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763 Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSNP------ 1078 TTT V P PT Q + VT T G Q + + + Sbjct: 3764 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3820 Query: 1079 -PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137 P T TT TT T + P T T TT T T + G Sbjct: 3821 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3872 Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197 TP I+ T + +Q T T+ +TT TV T P Sbjct: 3873 -----TPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT---------- 3915 Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 G ++P + ++ +P+ P +T T + G P P+ Sbjct: 3916 ----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310 +TT TVT P+ T TQ + P T T T T T TT+ Sbjct: 3972 ---------TTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017 Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370 + V P +T TT TT T+ T P G Q P T T T T Sbjct: 4018 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4077 Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430 P T++ T P+ TP T + P PT P T TT Sbjct: 4078 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4137 Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQ 1489 T T T T + P + + G T+ TTTV+ T T T TQ Sbjct: 4138 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQ 4194 Query: 1490 STPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDL 1549 + P S P EL S P + P Q +S S+ L ES +LS LP A+++ Sbjct: 4195 TGPPTHTSTAPIAELTTSNPPPESSTP-QTSRSTSSPLT-ESTTLLST-----LPPAIEM 4247 Query: 1550 SST-----------------------------GEPSSGQESAGSAVVATVVVQ 1573 +ST G P+ G + S+ VQ Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQ 4300 Score = 212 bits (540), Expect = 3e-54 Identities = 308/1287 (23%), Positives = 419/1287 (32%), Gaps = 165/1287 (12%) Query: 403 PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455 P T T +PTP P + P + P Q T IT P P Sbjct: 2498 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2557 Query: 456 -----PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLV--TMRPASQ 508 PTTT I TV + PT TQ P +T T TP T P + Sbjct: 2558 TGTQTPTTTPITTTTTVTPT----PTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 2612 Query: 509 --AGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565 VT T P G + T T + +P +G T + P+ P Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2672 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T P T I T VTP T T T ++P+ + T Q T+ T Sbjct: 2673 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 T+ P T + T T + TT T T T ++P + P + + Sbjct: 2732 TTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP-----------ITT 2777 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAG 745 P T T +T P+T T P P T + T+ TT +T T Sbjct: 2778 TTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2836 Query: 746 TKPT---ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801 PT I ++V+P+ T GT T T I + +T T +P +PIT TT Sbjct: 2837 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 2895 Query: 802 KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGT-ILR 847 T + T P T V T G Q T + P GT Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955 Query: 848 TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907 T P+ VTP TT + TT VT T TGT + T+ + Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPIT 3006 Query: 908 TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967 T T T +Q T IT + T G TPT T P++ T VT P+ Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3064 Query: 968 GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027 G + + + + TT PT T T + T T+ + P T TT Sbjct: 3065 GTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119 Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSN------- 1077 TTT V P PT Q + VT T G Q + + + Sbjct: 3120 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176 Query: 1078 PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137 P T TT TT T + P T T TT T T + G Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3228 Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197 TP I+ T + + QT T+ +TT TV T P Sbjct: 3229 -----TPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP----------- 3270 Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 G ++P + ++ +P+ P +T T + G P P+ Sbjct: 3271 ---TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310 +TT TVT P+ T TQ + P T T T T T TT+ Sbjct: 3328 ---------TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3373 Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370 + V P +T TT TT T+ T P G Q P T T T T Sbjct: 3374 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3433 Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430 P T++ T P+ TP T + P PT P T TT Sbjct: 3434 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3493 Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------L 1480 T T T T + P + + G T+ TTTV+ T Sbjct: 3494 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3553 Query: 1481 TRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGE 1530 T +TT T TP P P + P V+P P Q P + + +T Sbjct: 3554 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3613 Query: 1531 SAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVD 1583 + T + ++ T P+ Q + + T V P P PT + + Sbjct: 3614 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673 Query: 1584 QLS--LPQELMAEAQAGTTTLMVTGLT 1608 + P Q TTT + T T Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTT 3700 Score = 207 bits (526), Expect = 1e-52 Identities = 299/1240 (24%), Positives = 408/1240 (32%), Gaps = 156/1240 (12%) Query: 438 QPLTQVGITLLPQAAPAPPTTT----TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQ 493 QP T +T P PPTTT T V PT + PT T + VT Sbjct: 1881 QPTT---MTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTP 1934 Query: 494 ATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAA 552 TGT T P + VT T P G + T T + +P +G Sbjct: 1935 TPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992 Query: 553 AAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKT 612 T + P+ PT P T I T VTP T T T ++P+ + T Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTP 2051 Query: 613 AAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPG 672 Q T+ T T+ P T + T T + TT T T T ++P + P Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP- 2107 Query: 673 GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP 732 + + P T T +T P+T T P P T + T+ Sbjct: 2108 ----------ITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITT 2156 Query: 733 TTIITTTQASGAGTKPT---ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTS 788 TT +T T PT I ++V+P+ T GT T T I + +T T Sbjct: 2157 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2216 Query: 789 SPGIKSPITIITTKVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVL 835 +P +PIT TT T + T P T V T G Q T + Sbjct: 2217 TP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2275 Query: 836 KGAPGQPGT-ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSL 894 P GT T P+ VTP TT + TT VT T TGT + Sbjct: 2276 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--- 2332 Query: 895 AGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPV 954 T+ + T T T +Q T IT + T G TPT T P+ Sbjct: 2333 ------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PI 2384 Query: 955 SQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCS 1014 + T VT P+G + + + + TT PT T T + T T+ + Sbjct: 2385 TTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2439 Query: 1015 NPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSV 1071 P T TT TTT V P PT Q + VT T G Q + Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496 Query: 1072 VRVCSN-------PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAM 1124 + + P T TT TT T + P T T TT T T Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTP 2555 Query: 1125 SSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATG 1184 + G TP I+ T + + QT T+ +TT TV T Sbjct: 2556 TPTGTQ------------TPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTP 2601 Query: 1185 APCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTR 1244 P G ++P + ++ +P+ P +T T Sbjct: 2602 TP--------------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647 Query: 1245 SSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT--- 1301 + G P P+ +TT TVT P+ T TQ + P T T T Sbjct: 2648 TPTGTQTPTTTPI---------TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTP 2693 Query: 1302 ----TNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPC 1357 T T TT+ + V P +T TT TT T+ T P G Q P Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753 Query: 1358 ETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVC 1417 T T T T P T++ T P+ TP T + P PT Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813 Query: 1418 SNPPCETHETGTTHTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV 1476 P T TT T T T T + P + + G T+ TTTV Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2873 Query: 1477 SST---------LTRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPR 1517 + T T +TT T TP P P + P V+P P Q P Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933 Query: 1518 QLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP- 1576 + + +T + T + ++ T P+ Q + + T V P P Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993 Query: 1577 ------PTQSEVDQLS--LPQELMAEAQAGTTTLMVTGLT 1608 PT + + + P Q TTT + T T Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033 Score = 196 bits (497), Expect = 3e-49 Identities = 309/1297 (23%), Positives = 425/1297 (32%), Gaps = 209/1297 (16%) Query: 403 PATAATATSPTPNPVPSV-----------PANPPKSPAPAAAAPAVQPLTQVGITLLPQA 451 P T T PT P P + P+ P +P+P P+ P T T P Sbjct: 1441 PITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS--PPTTTTTTPPPTT 1498 Query: 452 APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVT--MRPASQA 509 P+PPTTT I T P S+ ++P T P T P TT +P T + P + Sbjct: 1499 TPSPPTTTPI----TPPASTTTLPPTT-TPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553 Query: 510 GKAPVTVTSLPAGVRMVVP----TQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565 P T T P P T S T S P ++ T PP++ P Sbjct: 1554 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTIT-----------TTTPPPTTTP 1602 Query: 566 ----TVLSVPAGTTIVKTMAVTP-----GTTTLPATVKVASSPVMVSNPATRMLKTAAAQ 616 T + P TT TP TTTLP T + P + P Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT-------- 1654 Query: 617 VGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSAL 676 T+ S T T+ P IT + T + + TT T T SP + P Sbjct: 1655 --TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTT--PSPTTTP----- 1705 Query: 677 ISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736 + P+ T+ T ++T P P P T+ PTT + Sbjct: 1706 ------------SSPI-TTTTTPSSTTTP--------SPPPTTMTTPSPTTTPSPPTTTM 1744 Query: 737 TTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSS--PGIKS 794 TT + T + L + + PS T P + T P + + TG S P Sbjct: 1745 TTLPPT---TTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHK 1801 Query: 795 PITIITTKVMTSGTGAPAKI---ITAVPKIATGH-GQQGVTQV----VLKGAPGQPGTIL 846 P G G A I T P + G GQ V V + K +PG + Sbjct: 1802 PGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV- 1860 Query: 847 RTVPMG-----GVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHS 901 +PM + + V+ TT T TT T T TV+ + G Sbjct: 1861 --IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTG--- 1915 Query: 902 TSASLATPITTLGTI----ATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQP 957 T TPITT T+ +Q T IT + T G TPT T P++ Sbjct: 1916 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTT 1973 Query: 958 TQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPP 1017 T VT P+G + + + + TT PT T T + T T+ + P Sbjct: 1974 TTVTPTPTPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2028 Query: 1018 CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRV 1074 T TT TTT V P PT Q + VT T G Q + + Sbjct: 2029 TGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2085 Query: 1075 CSN-------PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSV 1127 + P T TT TT T + P T T TT T T + Sbjct: 2086 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPT 2144 Query: 1128 GANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPC 1187 G TP I+ T + + QT T+ +TT TV T P Sbjct: 2145 GTQ------------TPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP- 2189 Query: 1188 SAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSV 1247 G ++P + ++ +P+ P +T T + Sbjct: 2190 -------------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2236 Query: 1248 GAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT------ 1301 G P P+ +TT TVT P+ T TQ + P T T T Sbjct: 2237 GTQTPTTTPI---------TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPT 2282 Query: 1302 -TNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH 1360 T T TT+ + V P +T TT TT T+ T P G Q P T Sbjct: 2283 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2342 Query: 1361 QTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNP 1420 T T T P T++ T P+ TP T + P PT P Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2402 Query: 1421 PCETHETGTTHTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST 1479 T TT T T T T + P + + G T+ TTTV+ T Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2462 Query: 1480 ---------LTRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLL 1520 T +TT T TP P P + P V+P P Q P + Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522 Query: 1521 QSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP---- 1576 + +T + T + ++ T P+ Q + + T V P P Sbjct: 2523 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2582 Query: 1577 ---PTQSEVDQLS--LPQELMAEAQAGTTTLMVTGLT 1608 PT + + + P Q TTT + T T Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619 Score = 130 bits (326), Expect = 2e-29 Identities = 213/978 (21%), Positives = 312/978 (31%), Gaps = 120/978 (12%) Query: 712 TKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKT 771 T P P T T+ PTT TT + + P + ++ P TT P T Sbjct: 1405 TPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP--ITTTTTPPPTTTPSPPISTTT 1462 Query: 772 IPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVT 831 P T + SP T TT + T +P P +T T Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST-------T 1515 Query: 832 QVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVS 891 + P P T T P +P T + + P +T + TT + T T T Sbjct: 1516 TLPPTTTPSPPTTTTTTPP--PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT-- 1571 Query: 892 TSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPT-IT 950 + + + P TT + T+++ PT T S TT T TTP+ T Sbjct: 1572 --------PPPTTTPSPPTTTTPSPPTITTTTPPPTT-TPSPPTTTTTTPPPTTTPSPPT 1622 Query: 951 MQPVSQPTQVTLI---TAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPG 1007 P++ PT T + T PS P + + PTT P+ +T + P Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682 Query: 1008 TVTLVCSNPPCETHETGTTNTA-----TTTVVANLGGHPQPTQVQFVCDRQEAAASLVTS 1062 + +PP T T + T TTT + P P S T+ Sbjct: 1683 SPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTT 1742 Query: 1063 TV----GQQNGSVVRVCSNPPCETHETGTTNTATTATS------NMAGQHGCSNPPCETH 1112 T+ S + PP T T + + TT T+ N G P H Sbjct: 1743 TMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKP--NFH 1800 Query: 1113 ETGTTNTATTAMSSVGANHQRDARRACAAGTP-----AVIRISVATGALEAAQGSK---- 1163 + G + G R P + V+ G + + K Sbjct: 1801 KPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860 Query: 1164 ---------------SQCQTRQTSATSTTM--TVMATGAPCSAGPLLGPSMAREPGGRSP 1206 +C T+ T+ T+TT T P + + P+ G ++P Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPT-PTPTGTQTP 1919 Query: 1207 AFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSP 1266 + ++ +P+ P +T T + G P P+ Sbjct: 1920 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--------- 1970 Query: 1267 STTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNAGSAQRVCSN 1319 +TT TVT P+ T TQ + P T T T T T TT+ + V Sbjct: 1971 TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2025 Query: 1320 PPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPD 1379 P +T TT TT T+ T P G Q P T T T T P Sbjct: 2026 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2085 Query: 1380 ATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT-TVTS 1438 T++ T P+ TP T + P PT P T TT T T T T Sbjct: 2086 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2145 Query: 1439 NMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------LTRAVTTVTQ 1489 + P + + G T+ TTTV+ T T +TT T Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205 Query: 1490 STPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGESAEVLSASQ 1539 TP P P + P V+P P Q P + + +T + Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2265 Query: 1540 TPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVDQLS--LPQE 1590 T + ++ T P+ Q + + T V P P PT + + + P Sbjct: 2266 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2325 Query: 1591 LMAEAQAGTTTLMVTGLT 1608 Q TTT + T T Sbjct: 2326 TPTGTQTPTTTPITTTTT 2343 Score = 105 bits (261), Expect = 6e-22 Identities = 137/564 (24%), Positives = 194/564 (34%), Gaps = 62/564 (10%) Query: 403 PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455 P T T +PTP P + P + P Q T IT P P Sbjct: 3786 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3845 Query: 456 ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 P TTT V PT + PT T + VT TGT T P Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3902 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565 + VT T P G + T T + +P +G T + P+ P Sbjct: 3903 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3960 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T P T I T VTP T T T ++P+ + T Q T+ T Sbjct: 3961 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4019 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 T+ P T + T T + TT T T T ++P + P + + Sbjct: 4020 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 4065 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744 P T T +T P+T T P P GT T TT+ T +G Sbjct: 4066 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 4124 Query: 745 GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801 T T I ++V+P+ T GT T T I + +T T +P +PIT TT Sbjct: 4125 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 4183 Query: 802 KVMT-----SGTGAPAKIITA-VPKIATGHGQQGVTQVVLKGAPGQP----GTILRTVPM 851 T + TG P TA + ++ T + + + P T+L T+P Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPP 4243 Query: 852 GGVRLVTPVTVSAVKPAVT----TLVVKGTT-----GVTTLGTVTGTVSTSLAGAGGHST 902 T + P T TL +T G T GT TG+ S +T Sbjct: 4244 AIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 4303 Query: 903 SASLATPITTLGTIATLSSQVINP 926 +++ T L T + + + + P Sbjct: 4304 TSAWTPTPTPLSTPSIIRTTGLRP 4327 Score = 97.8 bits (242), Expect = 9e-20 Identities = 186/848 (21%), Positives = 262/848 (30%), Gaps = 96/848 (11%) Query: 839 PGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAG 898 P P T P L P T + P TT TT + T T T + + Sbjct: 1399 PSPPTTTPSPPPTSTTTL--PPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456 Query: 899 GHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPT 958 ST+ + P TT T S P T S TT T TTP+ P Sbjct: 1457 PISTTTT-PPPTTTPSPPTTTPS----PPTTTPSPPTTTTTTPPPTTTPS--------PP 1503 Query: 959 QVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPC 1018 T IT P+ P P + TT PT T + + T TL + P Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563 Query: 1019 ETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNP 1078 T TT TTT P P + S T+T + +P Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT---PSP 1620 Query: 1079 PCETHETGTTNTAT---TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDA 1135 P T T T+T T T T + + PP T TT T + +++ Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT 1680 Query: 1136 RRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATS-----TTMT----VMATGAP 1186 + TP+ ++ T + S T +S T+ TTMT P Sbjct: 1681 PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPP 1740 Query: 1187 CSAGPLLGPSMAREPGGRSPAFVQLAPLS-SKVRLSSPSIKDLPAGRHSHAVSTAAMTRS 1245 + L P+ P +P + P + S ++P+ +P + + + Sbjct: 1741 TTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFH 1800 Query: 1246 SVGAGEPRMAPVC---------------ESLQGGSPSTTVTVTALEALLC------PSAT 1284 G + VC + G TV L+C P Sbjct: 1801 KPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860 Query: 1285 VTQV-CSN-------PPCETHETGTTNTA-------TTSNAGSAQRVCSNPPCETHETGT 1329 + C N C T T T T TT+ + V P +T T Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT 1920 Query: 1330 THTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVES 1389 T TT T+ T P G Q P T T T T P T++ T Sbjct: 1921 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1980 Query: 1390 GLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT-TVTSNMSSNQDPPP 1448 P+ TP T + P PT P T TT T T T T + P Sbjct: 1981 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2040 Query: 1449 AASDQGEVESTQGDSVNITSSSAITTTVSST---------LTRAVTTVTQSTPVPGP--- 1496 + + G T+ TTTV+ T T +TT T TP P P Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2100 Query: 1497 ----SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDL 1549 + P V+P P Q P + + +T + T + + Sbjct: 2101 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2160 Query: 1550 SSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVDQLS--LPQELMAEAQAGTT 1600 + T P+ Q + + T V P P PT + + + P Q TT Sbjct: 2161 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2220 Query: 1601 TLMVTGLT 1608 T + T T Sbjct: 2221 TPITTTTT 2228 Score = 43.9 bits (102), Expect = 0.002 Identities = 72/382 (18%), Positives = 107/382 (28%), Gaps = 26/382 (6%) Query: 1435 TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT---TVTQST 1491 T S ++ PPP ++ +T T++ TTT S +T T T T S Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456 Query: 1492 PVPGPSVPPPEELQVSPGPRQQLP-PRQLLQSASTALMGESAEVLSASQTPELPAAVDLS 1550 P+ + PPP +P P P P S T + S P S Sbjct: 1457 PISTTTTPPP---TTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513 Query: 1551 STGEPSSGQESAGSAVVAT--VVVQPPPPTQSEV----DQLSLPQELMAEAQAGTTTLMV 1604 +T P + S + T P PPT + + +LP TTT Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1573 Query: 1605 TGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQ 1664 TP T + + P T T T Sbjct: 1574 PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1633 Query: 1665 AELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSL- 1723 + TT P T + P P+ + Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT-------PPPTTTPSSPIT 1686 Query: 1724 NDPAIESNCLNELAGTV----PSTVALLPSTATESLAPSNTFVAPQPVVVAS-PAKLQAA 1778 P+ + + + T P T PS+ T P T P P S P Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT 1746 Query: 1779 ATLTEVANGIESLGVKPDLPPP 1800 T ++ + + + P + PP Sbjct: 1747 LPPTTTSSPLTTTPLPPSITPP 1768 Score = 33.9 bits (76), Expect = 1.7 Identities = 38/132 (28%), Positives = 56/132 (42%), Gaps = 22/132 (16%) Query: 359 LETEKPPPPARV-QLVRANTNSLEVSWGAVATADSYLLQLQKYDIPAT--AATATSP--T 413 L T PPP + Q R+ ++ L S ++T +++ P+T A T TS T Sbjct: 4209 LTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPP-AIEMTSTAPPSTPTAPTTTSGGHT 4267 Query: 414 PNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPT--TTTIQVLPTVPGSS 471 +P PS +PP +P G T +AP P T TTT P + Sbjct: 4268 LSPPPSTTTSPPGTPTR-------------GTTTGSSSAPTPSTVQTTTTSAWTPTP-TP 4313 Query: 472 ISVPTAARTQGV 483 +S P+ RT G+ Sbjct: 4314 LSTPSIIRTTGL 4325 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 189 bits (480), Expect = 2e-47 Identities = 367/1777 (20%), Positives = 615/1777 (34%), Gaps = 244/1777 (13%) Query: 379 SLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQ 438 S+ VS VA+ ++ L D + T+T + +P P+ + P S P Sbjct: 1635 SIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTP--- 1691 Query: 439 PLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSI----SVPTAARTQGVPAVLKVTGPQA 494 LT + + P A+ A T +T V + P ++ S PT + +P G Sbjct: 1692 -LTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTP 1750 Query: 495 TTGTPLVTM----RPASQAGKAPV-TVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAAL 549 T P+ T AS P+ T T + +A+GT I +S GM L Sbjct: 1751 LTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPL 1810 Query: 550 AAAAAATQKIPPSSAPTVLSVP--AGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPAT 607 + + + S A T+ + P + + +V + AV+ T T S+P + + Sbjct: 1811 TSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTP----SEGS 1866 Query: 608 RMLKTAAAQVGTSVSSATNT-STRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT---- 662 L + T SS TNT ST P +T + T AQ + TT G T T Sbjct: 1867 TALTSIPVSTTTVASSETNTLSTTPAVT--STPVTTYAQVSSSPTTADGSSMPTSTPREG 1924 Query: 663 ---LVKSPISVPG-GSALISNLGKVMSVVQTKPVQT------SAVTGQASTGPVTQIIQT 712 L P+S S+ I+ L ++ +T PV T S T ++ P + Sbjct: 1925 RPPLTSIPVSTTTVASSEINTLSTTLADTRT-PVTTYSQASSSPTTADGTSMPTPAYSEG 1983 Query: 713 KGPL---PAGTILKLVTSADGKPTTIITT----TQASGAGTKPTILGISSVSPSTTKPGT 765 PL P T L + + A TT + T T ++ + PT G +S+ ST T Sbjct: 1984 STPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERT 2043 Query: 766 TTII-KTIPMSAIITQAG----------ATGVTSSPGIKSPITIITTKVMTSGTGAPAKI 814 T + + + +++ G T VT+S S T + + S + + Sbjct: 2044 TPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPL 2103 Query: 815 ITAVPKIAT---------------GHGQQGVTQVVLKGAP-GQPGTILRTVPMGGVRL-V 857 +T++P T +T + +P GT ++T R + Sbjct: 2104 LTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPL 2163 Query: 858 TPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIA 917 T + VS A + + TT V T VT + + TS +TP + G+ Sbjct: 2164 TSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTP--SEGSTP 2221 Query: 918 TLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQ---PV 974 S V +T A+ + T T T + + S PT + P+ ++ P+ Sbjct: 2222 FTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPL 2281 Query: 975 HDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVV 1034 +PVS +E T + T DS P T + S+PP GT+ +T+ Sbjct: 2282 TSIPVSHTLVANSEVSTLSTTPVDSNT----PFTTSTEASSPPPTAE--GTSMPTSTSSE 2335 Query: 1035 ANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNP--------PCETHETG 1086 N P V + + S + + + S+P P T+ G Sbjct: 2336 GNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEG 2395 Query: 1087 TTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAA----- 1141 +T + S M + TH T +T+T +S A+ + Sbjct: 2396 STPLTSVPVSTMP----VVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPP 2451 Query: 1142 --GTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAR 1199 GT + + V+T + +++ TS TT T A+ +P +A ++ P Sbjct: 2452 SEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTE-ASSSPTTAEDIVVPISTA 2510 Query: 1200 EPGGR--SPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 G + V P++S + ++ P +S V++ ++ S+ A E P Sbjct: 2511 SEGSTLLTSIPVSTTPVASP---EASTLSTTPVDSNSPVVTSTEISSSATSA-EGTSMPT 2566 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVC 1317 +G +P ++ V+ ++T+ S P +T TT+T T+S+ +A+ Sbjct: 2567 STYSEGSTPLRSMPVSTKPLASSEASTL----STTPVDTSIPVTTSTETSSSPTTAKD-- 2620 Query: 1318 SNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSV--GA 1375 ++ P T +T + S E T TTSTGT+ S + G+ Sbjct: 2621 TSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGS 2680 Query: 1376 LLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATT 1435 +P +T R+ P T LLA N T T T+T Sbjct: 2681 SMPTSTPGERST---------PLTNILVSTTLLA---------NSEASTLSTTPVDTSTP 2722 Query: 1436 VTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVP- 1494 VT++ ++ P A + + S +TS T V+S+ V+T T +P Sbjct: 2723 VTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPV 2782 Query: 1495 -----GPSVPPPEELQVSP--GPRQQLPPRQLLQSASTALMGESAEVLSASQT-PELPAA 1546 S P E+ P P + P + T + A LS + P Sbjct: 2783 TTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVT 2842 Query: 1547 VDLSSTGEPSSGQ--------ESAGSAVVATVVVQPPPPTQSEVDQL-------SLPQEL 1591 ++ P++ + S GS ++ ++ V P SE L S+P Sbjct: 2843 TSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTT 2902 Query: 1592 MAEAQAGTTTLMVTGL---TPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMG 1648 E + TT T + TP E++ ++ + V A +A Sbjct: 2903 STEGSSSPTTAEGTSMPISTPSEVSTPLT--------------SILVSTVPVAGSEASTL 2948 Query: 1649 TGEPMDTSEAAATVTQAELGHLSAEG---------------QEGQATTIPIVLTQQELAA 1693 + P+DT T +A +AEG +T+P+ ++ + Sbjct: 2949 STTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLS 3008 Query: 1694 LVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATE 1753 + PT A ++ P+ S L + V +T +P +T Sbjct: 3009 RTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSI--PVSTTPVAIPEASTL 3066 Query: 1754 SLAP--SNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQ 1811 S P SN+ V V +SP + T + S G P P S P Sbjct: 3067 STTPVDSNSPVVTSTEVSSSPTPAEG----TSMPISTYSEGSTPLTGVPVSTTP------ 3116 Query: 1812 WFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGTAYKFRVAGINA 1871 VT + P D GT+ Sbjct: 3117 -------------VTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSM--------- 3154 Query: 1872 CGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQS 1931 P S S T L P + + S+ T V + + S + Sbjct: 3155 ----PTSTPSEGSTPLTYMPVSTMLVVSSEDS-----TLSATPVDTSTPVTTSTEATSST 3205 Query: 1932 SQAGGELKSSTPAQ--LAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEK 1989 + G + +STP++ V +P ++S LS +D T + E Sbjct: 3206 TAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP------LTTSTEA 3259 Query: 1990 GYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSA 2026 P T TS S G+ P P+S+ + S+ Sbjct: 3260 SSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASS 3296 Score = 187 bits (475), Expect = 9e-47 Identities = 320/1475 (21%), Positives = 545/1475 (36%), Gaps = 213/1475 (14%) Query: 379 SLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQ 438 S+ VS V T+++ L D T+T T +P + + P S P Sbjct: 2224 SMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTS 2283 Query: 439 -PLTQV--------GITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV 489 P++ ++ P + P TT+T P S+PT+ ++G + ++ Sbjct: 2284 IPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRM 2343 Query: 490 TGPQATT-----------GTPLVTMRPA---SQAGKAPVTV--TSLPAGVRMVVPTQSAQ 533 P +TT TP T P SQAG +P T TS+P T S Sbjct: 2344 --PVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTS------TYSEG 2395 Query: 534 GTVIGSSPQMSGMAALAAAAAATQKIP-PSSAPTVLSVPAGT-------TIVKTMAVTPG 585 T + S P +S M +++ A+ P +S P S A + T + T + G Sbjct: 2396 STPLTSVP-VSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG 2454 Query: 586 TTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQ 645 TT L A++ V+++PV+ S T L T T ++++T S+ P ++ A Sbjct: 2455 TTPL-ASMPVSTTPVVSSEAGT--LSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTAS 2511 Query: 646 QAQVVTTVVGGVTKTITLVKSPISVPGGSALISN-LGKVMSVVQTKPVQTSAVTGQASTG 704 + + T +I + +P++ P S L + + VV + + +SA + + ++ Sbjct: 2512 EGSTLLT-------SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSM 2564 Query: 705 PVTQIIQTKGPLPAGTI-LKLVTSADGK-----------PTTIITTTQASGAGTKPTILG 752 P + + PL + + K + S++ P T T T +S K T + Sbjct: 2565 PTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMP 2624 Query: 753 ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPA 812 IS+ S +T T+ ++ T+P+++ + A+ ++++P + T ++T+ TG + Sbjct: 2625 ISTPSEVSTSL-TSILVSTMPVAS----SEASTLSTTP-------VDTRTLVTTSTGTSS 2672 Query: 813 KIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTL 872 P A G T PG+ R+ P+ + + T + ++ ++T Sbjct: 2673 S-----PTTAEGSSMPTST-------PGE-----RSTPLTNILVSTTLLANSEASTLSTT 2715 Query: 873 VVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTL--GTIATLSSQV--INPTA 928 V +T VTT + + +T+ + ST + +TP+T++ T+ SS+ ++ TA Sbjct: 2716 PVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTA 2775 Query: 929 ITVSAAQTTLT-AAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPT- 986 + S TT T A+ TT +T P S P++ + V PV L++ Sbjct: 2776 VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPV 2835 Query: 987 -TEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTT-----NTATTTVVANLGGH 1040 T P T T A S + V P T G+T +TT V ++ Sbjct: 2836 DTSTPVTTSTKASSSPTTAEGIVV-------PISTASEGSTLLTSIPVSTTPVASSEAST 2888 Query: 1041 PQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTAT-TATSNMA 1099 T V + + + TST G + + S P E T T+ +T +A Sbjct: 2889 LSTTPV-------DTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVA 2941 Query: 1100 GQHGC--SNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVAT---G 1154 G S P +T TT+ ++ + TP + +SV+T Sbjct: 2942 GSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTP-LTSMSVSTMPVA 3000 Query: 1155 ALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPL 1214 + EA+ S++ T TST + T A + P+ PS P P V P+ Sbjct: 3001 SSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIP--VSTTPV 3058 Query: 1215 SSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTA 1274 + + ++ P +S V++ ++ S A E P+ +G +P T V V+ Sbjct: 3059 AIP---EASTLSTTPVDSNSPVVTSTEVSSSPTPA-EGTSMPISTYSEGSTPLTGVPVST 3114 Query: 1275 LEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTAT 1334 +++ S P +T TT+T E H + TT T Sbjct: 3115 TPV----TSSAISTLSTTPVDTSTPVTTST------------------EAHSSPTTSEGT 3152 Query: 1335 TATSNGGTGQPEGGQQPPAGRPCETHQTTST--GTTMSVSVGALLPDATSSHRTVESGLE 1392 + T P G P P T S+ T + V P TS+ T + E Sbjct: 3153 SMP----TSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAE 3208 Query: 1393 VAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTA-----TTVTSNMSSNQDPP 1447 + P+ TP G L P SN P + E T T +T++ ++ PP Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPV----SNTPVASSEASILSTTPVDSNTPLTTSTEASSSPP 3264 Query: 1448 PAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVP------GPSVPPP 1501 A + S +TS TTTV+S+ T ++T T P S PP Sbjct: 3265 TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPI 3324 Query: 1502 EELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQES 1561 + P L + + S+E + S TP VD +ST +S + S Sbjct: 3325 ADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP-----VD-TSTPVTTSTEAS 3378 Query: 1562 AGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAA 1621 + P++ S+P + TL T + L VT + EA+ Sbjct: 3379 LSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTL-VTTSTEAS 3437 Query: 1622 AQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATT 1681 + E GT P T+ +T +T Sbjct: 3438 SSPTIAE-------------------GTSLPTSTTSEGSTPLSIM-----------PLST 3467 Query: 1682 IPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVP 1741 P+ ++ + + PT A + + S L + + Sbjct: 3468 TPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT 3527 Query: 1742 STVALLPSTATESLAPSNTFVAPQPVVVASPAKLQ 1776 + ST + + SNTFV +SPA LQ Sbjct: 3528 PVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQ 3562 Score = 177 bits (450), Expect = 7e-44 Identities = 351/1572 (22%), Positives = 579/1572 (36%), Gaps = 234/1572 (14%) Query: 379 SLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVP----SVPANPP-KSPAPAAA 433 S+ S V ++++ L D T+T T +P S+P + P + P + Sbjct: 928 SMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTS 987 Query: 434 APAVQPLTQVG----ITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV 489 P L ++ P + P TT+T P S+PT+ ++G + ++ Sbjct: 988 TPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRM 1047 Query: 490 ----------------TGPQATTGTPLVTMRPASQAG--------------KAPVTVTSL 519 T P A T TP+ T AS + + +TS+ Sbjct: 1048 PVSTTMVASSETSTLSTTP-ADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSV 1106 Query: 520 PAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKI----------PPSSAPTVL- 568 P R+VV S++ + + ++P + + + A++ PPS T L Sbjct: 1107 PVSTRLVV---SSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLA 1163 Query: 569 SVPAGTT-IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT 627 S+P TT +V + A T TT + + +VA+S S P T A+V + +S Sbjct: 1164 SMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPT-------AEVTSMPTSTPGE 1216 Query: 628 STRPIITVHKSGTVTVAQQAQVVTT----VVGGVTKTITLVKSPISVPGGSALISNLGKV 683 + P+ ++ T + +A ++T VT + SP + G S S + Sbjct: 1217 RSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEG 1276 Query: 684 MSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL-----------PA-GTILKLVTSADGK 731 +++ + PV T+ VT ++ +T + TKGP+ PA GT + T ++G+ Sbjct: 1277 STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGR 1336 Query: 732 P--------TTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGA 783 TT++ ++ S T P + + V+ ST + T + M G Sbjct: 1337 TPLTSIPVNTTLVASSAISILSTTP-VDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGT 1395 Query: 784 TGVTSSPGIKSPI------TIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG 837 T +TS P +P+ T+ T V TS G + T+ P A G + Sbjct: 1396 TPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGIS-------IPTS 1448 Query: 838 APGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGA 897 P + T L+++P+ TPV S TT V + VT+ VS+S A Sbjct: 1449 TPSEGKTPLKSIPVSN----TPVANSEASTLSTTPVDSNSPVVTSTA-----VSSSPTPA 1499 Query: 898 GGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITM-QPVSQ 956 G TS +++TP + G+ A L+S ++ T + S + T +TP T Q S Sbjct: 1500 EG--TSIAISTP--SEGSTA-LTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSS 1554 Query: 957 PTQV---TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVC 1013 PT ++ T+ + P+ LPVS + ++E T + T DS + V T Sbjct: 1555 PTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDS-KTQVTAST----- 1608 Query: 1014 SNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVR 1073 E + T ++ T+ G P T + AS ST+ S Sbjct: 1609 -----EASSSTTAEGSSMTISTPSEGSPLLTSIPV---STTPVASPEASTL-----STTP 1655 Query: 1074 VCSNPPCETH-ETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQ 1132 V SN P T E ++ T TS + P + TT A++A+S++ Sbjct: 1656 VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLS---- 1711 Query: 1133 RDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPL 1192 T V + T + EA + T ++T + T T P S P+ Sbjct: 1712 ----------TTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPV 1761 Query: 1193 LGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKD---LPAGRHSHAVSTAAMTRSSVGA 1249 L S +P +S SSP+ + +P S ++ T S Sbjct: 1762 L--SSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTL 1819 Query: 1250 GEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSN 1309 A + S S VT TA+ + P+ + S P + + +TT+ Sbjct: 1820 VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTV 1879 Query: 1310 AGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTM 1369 A S S P T TT+ +++ G P GRP T ST T Sbjct: 1880 ASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVA 1939 Query: 1370 SVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGT 1429 S + L + V + + +++P T GT++ P P S P T Sbjct: 1940 SSEINTLSTTLADTRTPVTTYSQASSSP--TTADGTSM--PTPAYSEGSTP-----LTSM 1990 Query: 1430 THTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQ 1489 + T V S+ +S P + ST+G S T+ T++ ++ TT Sbjct: 1991 PLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGG---TSIQTSTPSERTTPLA 2047 Query: 1490 STPVPGPSVPPPE--ELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV 1547 PV V E L +P + S+S G S + + S+ L ++ Sbjct: 2048 GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSI 2107 Query: 1548 DLSSTGEPS--------SGQESAGSAVVATVVVQPPPPTQSEVDQ-----------LSLP 1588 LS+T S + +S + +T V P PT+ Q S+P Sbjct: 2108 PLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMP 2167 Query: 1589 QELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQ--------------ALA 1634 A + +TL T + VT + EA + +E ++ Sbjct: 2168 VSTTVVASSAISTLSTTPV-DTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMP 2226 Query: 1635 IQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEG--------QEGQA--TTIPI 1684 + + +A + P+DTS T T+A +AEG EG T+IP+ Sbjct: 2227 VSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPV 2286 Query: 1685 VLTQQELAALVQQQQLQEAQAQQQHHHLP----TEALAP---ADSLNDPAIESNCLNELA 1737 T LV ++ + P TEA +P A+ + P S+ N Sbjct: 2287 SHT------LVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL 2340 Query: 1738 GTVPSTVALLPS--TATESLAPSNTFVAPQPVVVASPA-KLQAAATLTEVANGIESLGVK 1794 +P + ++ S T+T S P++T PV S A A T + S G Sbjct: 2341 TRMPVSTTMVASFETSTLSTTPADT---STPVTTYSQAGSSPTTADDTSMPTSTYSEGST 2397 Query: 1795 PDLPPPPSKAPM 1806 P P S P+ Sbjct: 2398 PLTSVPVSTMPV 2409 Score = 177 bits (449), Expect = 9e-44 Identities = 335/1492 (22%), Positives = 559/1492 (37%), Gaps = 219/1492 (14%) Query: 401 DIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPT-TT 459 D P ++T +PT + S + + P++ P T G T +P + P+ + ++ Sbjct: 101 DTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEG-TDVPMSTPSEESISS 159 Query: 460 TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTG--TPLVTMRPASQAGKAPVTVT 517 T+ + T P S T+ + + T QA++ TP T P S + +T Sbjct: 160 TMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLT 219 Query: 518 SLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAA--TQKIPPS---SAPTVLSVPA 572 S+PA V +++ T++ + ++S ++A A++ T PS SAP+ S P Sbjct: 220 SMPASTMKVASSEAI--TLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPL 277 Query: 573 GTTIVKTM-AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP 631 + M V+ +TL T + PV+ S A+ TA GTS+ ++T T Sbjct: 278 TRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAE---GTSIPTSTYTEGST 334 Query: 632 IITVHKSGTVTVAQQAQVVTTVVGGVTKT-ITLVKSPISVPGGSALISNLGKVMSVVQTK 690 +T + T+ VA ++ T T +T P S+P T Sbjct: 335 PLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLP-----------------TT 377 Query: 691 PVQTSAVTGQASTG--PVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT------TTQAS 742 TS +T S G P+T +P TI LV S++ T+ I T AS Sbjct: 378 AEATSMLTSTLSEGSTPLTN-------MPVSTI--LVASSEASTTSTIPVDSKTFVTTAS 428 Query: 743 GAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTK 802 A + PT +S++ ST G+T + + + + A+ ++++P T +TT Sbjct: 429 EASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTP--VDSKTQVTTS 486 Query: 803 VMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAP--GQPGTILRTVPMGGVRLVTPV 860 S + P + ++P G +T + + P + L T P V TPV Sbjct: 487 TEAS-SSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTP---VDTSTPV 542 Query: 861 TV------SAVKPAVTTLVV----KGTTGVTTLGTVT--------GTVSTSLAGAGGHST 902 T S+ P T++ +G+T +T + T T ST+ A + T Sbjct: 543 TTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVT 602 Query: 903 SASLATPITTL--GTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960 ++S A+ +T GT S+ T IT + TTL A+ +T + T PV T V Sbjct: 603 TSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTT--PVDSNTPV 660 Query: 961 TLIT-APSGVEAQPVHDLPVSIL---ASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNP 1016 T T A S +P S ++P T P T +A S + S Sbjct: 661 TTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTL---------STT 711 Query: 1017 PCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQ--NGSVVRV 1074 P +T TT+T ++ G PT E + L + V + S Sbjct: 712 PVDTSTPVTTSTEASSSPTTADGASMPTSTP-----SEGSTPLTSMPVSKTLLTSSEAST 766 Query: 1075 CSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRD 1134 S P +T TT+T + CS T GT+ +T Sbjct: 767 LSTTPLDTSTHITTST----------EASCS----PTTTEGTSMPISTP----------- 801 Query: 1135 ARRACAAGTPAVIRISVATGAL---EAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGP 1191 + G+P + I V+ + EA+ S + + TST ++ T A ++ P Sbjct: 802 -----SEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMP 856 Query: 1192 LLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGE 1251 S R P P L S+ LS+ + S V+ + RSS E Sbjct: 857 TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDT------STPVTNSTEARSSPTTSE 910 Query: 1252 PRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAG 1311 P +G +P T++ + + + T+ S P +T TT+T TS+ Sbjct: 911 GTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTL----SATPVDTSTPVTTSTEATSSPT 966 Query: 1312 SAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTST--GTTM 1369 +A+ ++ P T GTT +T S+ E T TTST + Sbjct: 967 TAEG--TSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP 1024 Query: 1370 SVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGT 1429 + G +P +T S + P T ++A T + S P +T T Sbjct: 1025 PTAEGTSMPTSTPSE---------GSTPLTRMPVSTTMVASSETSTL-STTPADTSTPVT 1074 Query: 1430 THTATTVTSNMSSNQDPPPAASDQGEVESTQGD-----SVNITSSSAITTTVSSTLTRAV 1484 T++ + +S + P + +G T V+ +S+ TT V +++ Sbjct: 1075 TYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTT 1134 Query: 1485 TTVTQSTP--VPGPSVP--PPEELQVSPGPRQQLPPRQLL------QSASTALMGESAEV 1534 +T S+P G S+P PP E P +P L + ST + +V Sbjct: 1135 STEASSSPTTAEGTSIPTSPPSE---GTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQV 1191 Query: 1535 LSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAE 1594 ++++ P +++S + G+ S + ++ V+ P SE LS + Sbjct: 1192 ATSTEASSPPPTAEVTSMPTSTPGER---STPLTSMPVRHTPVASSEASTLSTSP---VD 1245 Query: 1595 AQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQAL----AIQAVLQAAQQAVMGTG 1650 TT T +P T A + + T E L + L + +A Sbjct: 1246 TSTPVTTSAETSSSP-----TTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLT 1300 Query: 1651 EPMDTSEAAATVTQAELGHLSAEG--------QEGQA--TTIPIVLTQQELAALVQQQQL 1700 P+DT T + AEG EG+ T+IP+ T LV + Sbjct: 1301 TPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTT------LVASSAI 1354 Query: 1701 QEAQAQQQHHHLP----TEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLA 1756 + P TEA + + ++ ++ N GT P T +P + T ++ Sbjct: 1355 SILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNS--NPSEGTTPLT--SIPVSTTPVVS 1410 Query: 1757 PSNTFVAPQPVVVASPAKLQAAATLT-EVANGIESLGVKPDLPPPPSKAPMK 1807 + ++ PV ++P A AT + A GI P P K P+K Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISI----PTSTPSEGKTPLK 1458 Score = 175 bits (444), Expect = 4e-43 Identities = 312/1471 (21%), Positives = 570/1471 (38%), Gaps = 161/1471 (10%) Query: 373 VRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAA 432 V + S+ VS VA++++ L D T+T + +P + ++ P S Sbjct: 2631 VSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER 2690 Query: 433 AAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP 492 + P L V TLL + + +TT + +S V T+A P + T Sbjct: 2691 STPLTNIL--VSTTLLANSEASTLSTTPVD-------TSTPVTTSAEASSSPTTAEGTSM 2741 Query: 493 QATT----GTPL----VTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMS 544 + +T TPL V+ P + + + V+ T++ + + T+++ SSP + Sbjct: 2742 RISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEAS------SSPTTA 2795 Query: 545 GMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATV--KVASSP--- 599 + ++ + + P +S P V P ++ T++ TP T+ P T K +SSP Sbjct: 2796 EVTSMPTSTPSETSTPLTSMP-VNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854 Query: 600 ----VMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVG 655 V +S + + V T+ +++ ST V S VT + + T Sbjct: 2855 EGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE 2914 Query: 656 GVTKTITLVKSPISVPGGSALISNL---GKVMSVVQTKPVQT------------SAVTGQ 700 G + I+ S +S P S L+S + G S + T PV T S T + Sbjct: 2915 GTSMPIS-TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAE 2973 Query: 701 ASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPST 760 ++ P++ + + PL + ++ + ++ T T S P + S T Sbjct: 2974 GTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTS----TPVTTSTEASSSPT 3029 Query: 761 TKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVM-TSGTGAPAKIITAVP 819 T GT I T G+T +TS P +P+ I + T+ + + ++T+ Sbjct: 3030 TAEGTGIPIST-------PSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTE 3082 Query: 820 KIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTG 879 ++ +G + + + G T L VP+ TPVT SA+ TT V +T Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGS--TPLTGVPVS----TTPVTSSAISTLSTT-PVDTSTP 3135 Query: 880 VTTLGTVTGTVSTSLAGAGGHSTSASLATPITTL--GTIATLSSQ--VINPTAITVSAAQ 935 VTT + +TS + ST + +TP+T + T+ +SS+ ++ T + S Sbjct: 3136 VTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195 Query: 936 TTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVT 995 TT T A TT T P S P++ V PV SIL++ + T T Sbjct: 3196 TTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTT 3255 Query: 996 IADSGQGDVQPGTV--TLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQ 1053 S + P T T + ++ P E T+ +TT VA+ ++ + Sbjct: 3256 ---STEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVAS-------SETSTLSTTP 3305 Query: 1054 EAAASLVTSTVGQQNGSVVRVCSNPPCETHETGT---TNTATTATSNMAGQHG-CSNPPC 1109 ++ VT+ + + ++ P T+ G+ TN + + T ++ + S P Sbjct: 3306 ADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPV 3365 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTR 1169 +T TT+T ++S A + + GT + + V+T + +++ + Sbjct: 3366 DTSTPVTTST-EASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPV 3424 Query: 1170 QTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLS-SKVRLSSPSIKDL 1228 ++ TT T ++ + G L S E G +P + + PLS + V S S Sbjct: 3425 DSNTLVTTSTEASSSPTIAEGTSLPTSTTSE--GSTP--LSIMPLSTTPVASSEASTLST 3480 Query: 1229 PAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQV 1288 S V+T++ T SS E P + +G +P T + V+ ++T+ Sbjct: 3481 TPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTL--- 3537 Query: 1289 CSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGG 1348 S P +++ T+++ +S+ + Q + + + T +++ + + Sbjct: 3538 -STTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTP 3596 Query: 1349 QQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVT-PQAGTAL 1407 P R +T + +T + LP +T S + + + SVT +AGTA Sbjct: 3597 STPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTAS 3656 Query: 1408 LAPFPTQ-------RVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQ 1460 P T +V S+P GTT T + + P + + E + Sbjct: 3657 TLPVDTSTPVITSTQVSSSP---VTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGST 3713 Query: 1461 GDSVNITSSSAITTT---VSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPR 1517 + ++ +S+ +TT+ +SS+ T TT++ S P+ ++ + +P R Sbjct: 3714 LSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESST 3773 Query: 1518 QLLQSASTAL-MGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQP-P 1575 + S T++ M ++E S+ T E + +S+T E S+ ++ TV++ P Sbjct: 3774 PSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERST--------LLTTVLISPIS 3825 Query: 1576 PPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAI 1635 + SE LS P T+T ++T ++ A + +E + L Sbjct: 3826 VMSPSEASTLSTP-------PGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTT 3878 Query: 1636 QAVLQAAQQAVMGTG----EPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQEL 1691 V + G P+DTS T TIP+ T Sbjct: 3879 LLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDT-----------ASTPTIPVATT---- 3923 Query: 1692 AALVQQQQLQEAQAQQQHHHLPTEAL---------APADSLNDPAIESNCLNELAGTVPS 1742 + + E +P+ + A +++ P I S LN + + S Sbjct: 3924 ---ISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSS 3980 Query: 1743 TVALLPSTATESLAPSNTFVAPQPVVVASPA 1773 T ST E P+ T AP V S A Sbjct: 3981 TTTSF-STTKEFTTPAMTTAAPLTYVTMSTA 4010 Score = 175 bits (443), Expect = 5e-43 Identities = 332/1490 (22%), Positives = 554/1490 (37%), Gaps = 225/1490 (15%) Query: 360 ETEKPPPP--ARVQLVRANTNSLEVSWGAVATA-----DSYLLQLQKYDI--PATAATAT 410 +T P P V + + S+ + V+TA ++Y K D+ P T +T Sbjct: 135 DTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQA 194 Query: 411 SPTPN-----------------PVPSVPANPPKSPAPAAAAPAVQPLT-QVGITLLPQAA 452 S +P P+ S+PA+ K + A P+ +T+ QA+ Sbjct: 195 SSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQAS 254 Query: 453 PAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATT--GTPLVTMRP---AS 507 +P T P++ S+ S + T+ +V+ V +A+T TP T P ++ Sbjct: 255 SSPTTAEG----PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITST 310 Query: 508 QAGKAPVTV--TSLPA-----GVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIP 560 +A +P T TS+P G + T ++ V S + + + T Sbjct: 311 EASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTE 370 Query: 561 PSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPA---TRMLKTAAAQV 617 PSS PT + T + TP T +T+ VASS ++ ++ T A++ Sbjct: 371 PSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEA 430 Query: 618 GTSVSSATNTS---------TRPIITVHKSGT-VTVAQQAQVVTTVVGGVTKTITLVKSP 667 +S ++A +TS + P+ ++ S T V ++ + + TT V T+ T ++ Sbjct: 431 SSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEAS 490 Query: 668 ISVP--------------GGSALISNLGKVMSVVQTK-------------PVQTSAVTGQ 700 S P G + L S M V ++ PV TS+ Sbjct: 491 SSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS 550 Query: 701 ASTGPVTQIIQTKGPLPAGTIL-------KLVTSADGKPTT-------IITTTQASGAGT 746 +ST P I T P T L +LV S++ T+ TT + + + Sbjct: 551 SSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSS 610 Query: 747 KPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTS 806 T G S + + ++ GTT ++ + + + +T T+ +P+T +T+ +S Sbjct: 611 STTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT-TSTEATSS 669 Query: 807 GTGAPAKIITAVPKIATGHGQQGVTQVVLKG--APGQPGTILRTVPMGGVRLVTPVTVSA 864 T A T++P G +T + + + L T P+ VT T ++ Sbjct: 670 STTAEG---TSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS 726 Query: 865 VKPAV-------TTLVVKGTTGVTTL--------GTVTGTVSTSLAGAGGHSTSASLA-- 907 P T+ +G+T +T++ + T+ST+ H T+++ A Sbjct: 727 SSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASC 786 Query: 908 TPITTLGT---IATLSSQVINPTAITVSAAQTTLTAAGGL-TTPTITMQPVSQPTQVTLI 963 +P TT GT I+T S T+I VS T A L TTP + PV+ T+V+ Sbjct: 787 SPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVS-- 844 Query: 964 TAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHET 1023 ++P+ E + S +P T P +T +A S + S P +T Sbjct: 845 SSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTL---------STTPVDTSTP 895 Query: 1024 GTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETH 1083 T +T + G PT + S+ ST + S R S P +T Sbjct: 896 VTNSTEARSSPTTSEGTSMPTSTP--GEGSTPLTSMPDSTTPVVS-SEARTLSATPVDTS 952 Query: 1084 ETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGT 1143 T T+T ATS+ G S P T T + TT ++S +H A + Sbjct: 953 TPVT--TSTEATSSPTTAEGTSIP------TSTPSEGTTPLTSTPVSHTLVANSEAS--- 1001 Query: 1144 PAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGG 1203 L + T T A+S T T P S PS P Sbjct: 1002 -----------TLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTST-----PSEGSTPLT 1045 Query: 1204 RSPAFVQLAPLSSKVRLS-SPSIKDLPAGRHSHAVSTA------AMTRSSVGAGEPRM-- 1254 R P + S LS +P+ P +S A S++ +M S+ G + Sbjct: 1046 RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTS 1105 Query: 1255 APVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNP--------PCETHETGTTNTA- 1305 PV L S ++T++ T ++ + P T T+ S+P P GTT A Sbjct: 1106 VPVSTRLVVSSEASTLSTTPVDTSI-PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLAS 1164 Query: 1306 ----TTSNAGSAQRVCSNPPCETHETGTTHT------ATTATSNGGTGQPEGGQQPPAGR 1355 TT S S P ++ T T T ++ T P P Sbjct: 1165 MPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSM 1224 Query: 1356 PC-ETHQTTSTGTTMSVSVGALLPDATSSHRTVES--GLEVAAAPSVTPQAGTALLAPFP 1412 P T +S +T+S S T+S T S E + P+ T G+ LL P Sbjct: 1225 PVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP 1284 Query: 1413 -TQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSA 1471 + + ++P T T T V ++ + P PA + +TS Sbjct: 1285 VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPV 1344 Query: 1472 ITTTVSSTLTRAVTT--VTQSTPV----PGPSVPPPEELQVSP--GPRQQLPPRQLLQSA 1523 TT V+S+ ++T V STPV S P E P P + P + + Sbjct: 1345 NTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS 1404 Query: 1524 STALMGESAEVLSASQT-PELPAAVDLSSTGEPSSGQ--------ESAGSAVVATVVVQP 1574 +T ++ A LSA+ P +T P++ + S G + ++ V Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN 1464 Query: 1575 PPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEE---LAVTAAAEAAAQAAATEEAQ 1631 P SE LS + + + T+T + + TP E +A++ +E + Sbjct: 1465 TPVANSEASTLS-TTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALT------ 1517 Query: 1632 ALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATT 1681 ++ + A+ + + P TS T +QA +A+G Q +T Sbjct: 1518 SIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTST 1567 Score = 174 bits (442), Expect = 6e-43 Identities = 315/1466 (21%), Positives = 548/1466 (37%), Gaps = 175/1466 (11%) Query: 379 SLEVSWGAVATADSYLLQLQKYD--IPATAAT--ATSPTPNPVPSVPANPPKSPAPAAAA 434 S+ VS VA++++ + D IP T +T ++SPT V S+P + P + Sbjct: 2755 SILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETST---- 2810 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSI----SVPTAARTQGVPAVLKVT 490 PLT + + P A+ T +T V + P ++ S PT A VP Sbjct: 2811 ----PLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASE 2866 Query: 491 GPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQ------SAQGTVIGSSPQMS 544 G T P+ T P + + + ++ T + + + T+ +A+GT + S Sbjct: 2867 GSTLLTSIPVSTT-PVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSE 2925 Query: 545 GMAALAAAAAATQKIPPSSAPTVLSVPAGT-TIVKTMA-VTPGTTTLPATVKVASSPVMV 602 L + +T + S A T+ + P T T V T A + TT T S+P Sbjct: 2926 VSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGER 2985 Query: 603 SNPATRM----LKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQV-VTTVVGGV 657 P T M + A+++ T + +TST + S + T A+ + ++T G Sbjct: 2986 RTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045 Query: 658 TK--TITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG----------- 704 T +I + +P+++P S L + S V T +S+ T T Sbjct: 3046 TPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGST 3105 Query: 705 PVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPG 764 P+T + + P+ + I L T+ T + T+T+A + PT +S+ ST G Sbjct: 3106 PLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSS---PTTSEGTSMPTSTPSEG 3162 Query: 765 TTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATG 824 +T + +P+S ++ + S+ + + + T+ TS T A T++P Sbjct: 3163 STPLTY-MPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG---TSIPTSTPS 3218 Query: 825 HGQQGVTQVVLKGAP--GQPGTILRTVPMGGVRLVTPVTVSAVKPAV-------TTLVVK 875 G +T V + P +IL T P+ +T T ++ P T+ + Sbjct: 3219 EGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSE 3278 Query: 876 GTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAI---TVS 932 G+T +T++ T TV++S +T A +TP+TT A+ S + + T++ T S Sbjct: 3279 GSTPLTSMPVSTTTVASSETSTLS-TTPADTSTPVTTYSQ-ASSSPPIADGTSMPTSTYS 3336 Query: 933 AAQTTLTAAGGLTTP-------TITMQPVSQPTQVTLIT----APSGVEAQPVHDLPVSI 981 T LT TTP T++ PV T VT T +P+ E + S Sbjct: 3337 EGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSE 3396 Query: 982 LASPTTEQPTATVTIADSGQGDVQPGTV---TLVCSNPPCETHETGTTNTATTTVVANLG 1038 +P P +T + S + V TLV ++ + T T+ T + G Sbjct: 3397 GTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEG 3456 Query: 1039 GHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNM 1098 P + AS +++T + V S+P T+ + TT T+ ++ Sbjct: 3457 STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTT--SSP---TNSSPTTAEVTSMPTST 3511 Query: 1099 AGQHGC--SNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGAL 1156 AG+ +N P T ++ +T + + V +N + A+ +PA ++++ T + Sbjct: 3512 AGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQ-ASSSPATLQVT--TMRM 3568 Query: 1157 EAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGR-SPAFVQLAPLS 1215 S T S+T T + +T + S + + + +P V P+S Sbjct: 3569 STPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMS 3628 Query: 1216 SKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEP----RMAPVCESLQGGSPSTTVT 1271 + +S+P + +P VST ++T S G PV S Q S T Sbjct: 3629 TPSEVSTP-LTIMP-------VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPE 3680 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T + + PS T + + P T T + + S V ++ P T + Sbjct: 3681 GTTMP-IWTPSEGSTPLTTMPVSTTRVTSSEGSTL-----STPSVVTSTPVTTSTEAISS 3734 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 +AT ++ P + ++ GTT+ VS + SS ++ S Sbjct: 3735 SATLDSTTMSVSMPM--------------EISTLGTTILVSTTPVTRFPESSTPSIPS-- 3778 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTS------NMSSNQD 1445 V + S+T A +P + + P T E T T ++ + +S Sbjct: 3779 -VYTSMSMTT-ASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLS 3836 Query: 1446 PPPAASDQGEVESTQGDSVNI-----TSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 PP + + ST+ S +I T +IT+ S+ LT + + T T PG S+ Sbjct: 3837 TPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIAS 3896 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQE 1560 L S S TA TP +P A +S + Sbjct: 3897 TPPLDTST---------TFTPSTDTA------------STPTIPVATTISVS------VI 3929 Query: 1561 SAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA 1620 + GS T+ + P T S D + A G + V T T+++ Sbjct: 3930 TEGSTPGTTIFIPSTPVTSSTAD--------VFPATTGAVSTPVITSTELNTPSTSSSST 3981 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 + T+E A+ + T+ T + + L S T Sbjct: 3982 TTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVT 4041 Query: 1681 TIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTV 1740 T P+ + + H P A + ++N A+ + T Sbjct: 4042 TRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTR----TK 4097 Query: 1741 PSTVALLPSTATESLAPSNTFVAPQP 1766 PST T T + P+NT + P Sbjct: 4098 PSTRTTSFPTVTTTAVPTNTTIKSNP 4123 Score = 164 bits (415), Expect = 8e-40 Identities = 296/1237 (23%), Positives = 468/1237 (37%), Gaps = 203/1237 (16%) Query: 374 RANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAA 433 R S+ VS VA++++ L D T+T + +P + P S + Sbjct: 2986 RTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045 Query: 434 APAVQPLTQVGITLLPQAAPAPPTTTTIQV---LPTVPGSSISV-PTAARTQGVPAVLKV 489 P LT + ++ P A P T +T V P V + +S PT A +P Sbjct: 3046 TP----LTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYS 3101 Query: 490 TGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAAL 549 G TG P+ T S A T+++ P V T T SSP S ++ Sbjct: 3102 EGSTPLTGVPVSTTPVTSSAIS---TLSTTPVDTSTPVTTS----TEAHSSPTTSEGTSM 3154 Query: 550 AAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGT-TTLPATVKVASSPVMVSNPATR 608 P+S P+ S P V TM V +TL AT S+PV S AT Sbjct: 3155 -----------PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATS 3203 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVV-TTVVGGVTKTITLVKS- 666 + TS S T P+ +V S T + +A ++ TT V T T ++ Sbjct: 3204 STTAEGTSIPTSTPSEGMT---PLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260 Query: 667 -----------PISVPG-GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKG 714 P S P GS ++++ + V + T + T ++ PVT Q Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASS 3320 Query: 715 --PLPAGTILKLVTSADGKP--------TTIITTTQASGAGTKP-------TILGISSVS 757 P+ GT + T ++G TT + +++AS T P T +S+S Sbjct: 3321 SPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS 3380 Query: 758 PSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTK-------VMTSGTGA 810 P TT GT+ I T S T + V+++P + S + ++T V TS + Sbjct: 3381 P-TTAEGTS--IPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEAS 3437 Query: 811 PAKII---TAVPKIATGHGQQGVTQVVLKGAP--GQPGTILRTVPMGGVRLVTPVTVSA- 864 + I T++P T G ++ + L P + L T P V TPVT S+ Sbjct: 3438 SSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTP---VDTSTPVTTSSP 3494 Query: 865 ---------VKPAVTTLVVKGTTGVTTLGTVT--------GTVSTSLAGAGGHSTSASLA 907 V T+ +G+T +T + T T+ST+ + TS+S A Sbjct: 3495 TNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQA 3554 Query: 908 TP------ITTLGTI------ATLSSQVINPTAITVSAAQTTLTAAGGLTTP-TITMQPV 954 + +TT+ ++L++ +++ T +T S A T T + +TP T + Q Sbjct: 3555 SSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSN 3614 Query: 955 SQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTAT--VTIADSGQGDVQP-GTVTL 1011 S PT +IT P ++ +++P T P +T VTI+++G P T T Sbjct: 3615 STPTPPEVITLPMSTPSE---------VSTPLTIMPVSTTSVTISEAGTASTLPVDTSTP 3665 Query: 1012 VCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSV 1071 V ++ + T + G P T + + VTS+ G S Sbjct: 3666 VITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTM--------PVSTTRVTSSEGSTL-ST 3716 Query: 1072 VRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANH 1131 V ++ P T +++AT ++ M+ + P E GTT +T Sbjct: 3717 PSVVTSTPVTTSTEAISSSATLDSTTMS-----VSMPMEISTLGTTILVSTT-------- 3763 Query: 1132 QRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGP 1191 R + TP++ + + A++GS S T+ TT M+T + S Sbjct: 3764 --PVTRFPESSTPSIPSVYTSMSMTTASEGSSSP-----TTLEGTTTMPMSTTSERST-- 3814 Query: 1192 LLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGE 1251 LL V ++P+S + S S P G S + T+ S E Sbjct: 3815 LL-------------TTVLISPISV-MSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAE 3860 Query: 1252 PRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT--TNTATTSN 1309 + + + +P TT+ V+ P A++ S PP +T T T T+TA+T Sbjct: 3861 VTTIRISITSERSTPLTTLLVSTTLPTSFPGASIA---STPPLDTSTTFTPSTDTASTPT 3917 Query: 1310 AGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTM 1369 A + + E GTT + T P T +T +T Sbjct: 3918 IPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTS 3977 Query: 1370 SVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGT 1429 S S + S+ + + AAP TA P T R C+ T T Sbjct: 3978 SSSTTT----SFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATST 4033 Query: 1430 THTATTVT-------------SNMSSNQDP---PPAASDQGEVESTQGDSVNITSSSAIT 1473 HT+T+VT S ++S+ P PPA S S +VN + + +T Sbjct: 4034 PHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMT 4093 Query: 1474 T-TVSSTLTRAVTTVT----------QSTPVPGPSVP 1499 T T ST T + TVT +S P P+VP Sbjct: 4094 TRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVP 4130 Score = 85.5 bits (210), Expect = 5e-16 Identities = 185/862 (21%), Positives = 304/862 (35%), Gaps = 140/862 (16%) Query: 978 PVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANL 1037 P L+ T + T+ + S V +T S E+ TT ++T + Sbjct: 79 PRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSS 138 Query: 1038 GGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGT--TNTATTAT 1095 P+ T V +E+ +S + + V P E + + T + +T T Sbjct: 139 PTTPEGTDVPMSTPSEESISSTM---------AFVSTAPLPSFEAYTSLTYKVDMSTPLT 189 Query: 1096 SNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGA 1155 ++ + P T T + +T ++S+ A+ + A + IS Sbjct: 190 TSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEIS----- 244 Query: 1156 LEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSA-GPLLG---PSMAREPGGRSPAFVQL 1211 T T++ A+ +P +A GP L PS P R P V L Sbjct: 245 ------------------TPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVML 286 Query: 1212 APLSSKVRLSS-PSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTV 1270 S LS+ P+ ++P V T+ SS E P +G +P T+ Sbjct: 287 VVSSEASTLSTTPAATNIP-------VITSTEASSSPTTAEGTSIPTSTYTEGSTPLTST 339 Query: 1271 TVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTT 1330 + + +T+ S P +T TT+T +S +A+ T Sbjct: 340 PASTMPVATSEMSTL----SITPVDTSTLVTTSTEPSSLPTTAE--------------AT 381 Query: 1331 HTATTATSNGGTGQPEGGQQPPAGRPCET-------HQTTSTGTTMSVSVGALLPDATSS 1383 T+ S G T P P T TTST S + +A+SS Sbjct: 382 SMLTSTLSEGST--------PLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSS 433 Query: 1384 HRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTA-----TTVTS 1438 T E + + TP G+ L P S P + E T T VT+ Sbjct: 434 PTTAED----TSIATSTPSEGSTPLTSMPV----STTPVASSEASNLSTTPVDSKTQVTT 485 Query: 1439 NMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST--LTRAVTTVTQSTPVPGP 1496 + ++ PP A + + S +TS S T V+S+ T + T V STPV Sbjct: 486 STEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTS 545 Query: 1497 SVPPPEELQVSPGPRQQLPPRQLLQSASTAL--MGESAEVLSASQTPELPAAVDLSSTGE 1554 S E S P P ST L M S ++ +S+ S+T Sbjct: 546 S----EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFV 601 Query: 1555 PSSGQESAGSAVVATVVVQPPPPTQSE----VDQLSLPQELMAEAQAGT-TTLMVTGLTP 1609 +S + S+ S + P T SE + +S+ L+A ++A T +T V TP Sbjct: 602 TTSSEASSSSTTAEGTSM--PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTP 659 Query: 1610 EELAVTAAAEAAAQAAATEEAQ--------------ALAIQAVLQAAQQAVMGTGEPMDT 1655 VT + EA + + E ++ + L A+ +A + P+DT Sbjct: 660 ----VTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDT 715 Query: 1656 SEAAATVTQAELGHLSAEG--------QEGQA--TTIPI---VLTQQELAAL--VQQQQL 1700 S T T+A +A+G EG T++P+ +LT E + L Sbjct: 716 STPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTS 775 Query: 1701 QEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNT 1760 + PT + ++ P+ S L + ++ + ST + + SN+ Sbjct: 776 THITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNS 835 Query: 1761 FVAPQPVVVASPAKLQAAATLT 1782 V V +SP + + T Sbjct: 836 PVTTSTEVSSSPTPAEGTSMPT 857 Score = 69.3 bits (168), Expect = 4e-11 Identities = 109/489 (22%), Positives = 180/489 (36%), Gaps = 57/489 (11%) Query: 332 TRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRANTNSLEVSWGAV--AT 389 T + IW+ +G V + E P+ V T++ +S A +T Sbjct: 3682 TTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDST 3741 Query: 390 ADSYLLQLQKYDIPATAATATSPTP----NPVPSVPANPPKSPAPAAAAPAVQPLTQVGI 445 S + ++ + T +T+P + PS+P+ A+ + P T G Sbjct: 3742 TMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGT 3801 Query: 446 TLLPQAAPAPPTT--TTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTM 503 T +P + + +T TT+ + P S+ P+ A T ++ P T TPL+T Sbjct: 3802 TTMPMSTTSERSTLLTTVLISPI----SVMSPSEAST--------LSTPPGDTSTPLLTS 3849 Query: 504 RPASQAGKAPVTVTSLPAGV---RMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIP 560 A P VT++ + R T T + +S + +A+ +T P Sbjct: 3850 TKAGSFS-IPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTP 3908 Query: 561 PSSAPTVLSVPAGTTI---VKTMAVTPGTT--------------TLPATVKVASSPVMVS 603 + + ++P TTI V T TPGTT PAT S+PV+ S Sbjct: 3909 STDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITS 3968 Query: 604 NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITL 663 T+++ TS S+ +T + T VT++ T G T + + Sbjct: 3969 TELNTP-STSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSAST 4027 Query: 664 VKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL----PAG 719 + S S P S ++ T+PV S+ + + ST I T P P Sbjct: 4028 L-SATSTPHTSTSVT----------TRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPT 4076 Query: 720 TILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIIT 779 T T TT+ T T+ S T + ++V +TT T T+P + Sbjct: 4077 TSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCF 4136 Query: 780 QAGATGVTS 788 G S Sbjct: 4137 GDGCQNTAS 4145 >gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] Length = 5765 Score = 164 bits (416), Expect = 6e-40 Identities = 313/1330 (23%), Positives = 463/1330 (34%), Gaps = 188/1330 (14%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 + T ++ V G+ ATA S P + TAT+PT V S A P SP A A Sbjct: 3729 STTATVTVPTGSTATASSTQATA---GTPHVSTTATTPT---VTSSKATPFSSPGTATAL 3782 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 PA++ A P+ TT L S + PTA + P+ T A Sbjct: 3783 PALRSTATTPTATSFTAIPSSSLGTTWTRL-----SQTTTPTATMSTATPS---STPETA 3834 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMV-VPTQSAQGTVI--GSSPQMSGMAALAA 551 T T L T ++A + T +S P VPT + G + SSP G A Sbjct: 3835 HTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSP---GTARTPP 3891 Query: 552 AAAATQKIPPSSAPTVL--SVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRM 609 +T P +S TV SVP GTT T+ T TT ++ SS S + Sbjct: 3892 VWISTTTTPTTSGSTVTPSSVP-GTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSL 3950 Query: 610 LKTAAAQVGTSVSSATNTSTRPIIT-----VHKSGTVTVAQQAQVVTTVVGGVTKTITLV 664 + TA T+ S TN S+ P T + + T A + V + G T T + Sbjct: 3951 ITTATTI--TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVP 4008 Query: 665 KSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKL 724 + + G S S+ V + TSA +G T +T+ PA T Sbjct: 4009 NTTATTHGRSLSPSSPHTV------RTAWTSATSGTLGTTHITEPSTGTSHTPAAT---- 4058 Query: 725 VTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGAT 784 T T +++ S T+ S SP TT PG TT +A ++ + Sbjct: 4059 -TGTTQHSTPALSSPHPSSRTTE------SPPSPGTTTPGHTTATSRTTATATPSKTRTS 4111 Query: 785 GVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG------- 837 + S +PIT + T + + P G + Sbjct: 4112 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ 4171 Query: 838 -------APGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTV 890 A QPG VP+G + V ++ LV + V Sbjct: 4172 PLGLECRAQAQPG-----VPLGELGQVVECSLD------FGLVCRNREQVGKFKMCFNYE 4220 Query: 891 STSLAGAGGHSTS----ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT 946 GH S +S A P +T GT L T +T +A TT + G T Sbjct: 4221 IRVFCCNYGHCPSTPATSSTAMPSSTPGTTWIL-------TELTTTA--TTTASTGSTAT 4271 Query: 947 PTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQP 1006 P+ T P ++T+P+ P + + T+ T T Sbjct: 4272 PSSTPGTAPPP---KVLTSPA--------TTPTATSSKATSSSSPRTATTLPVLTSTATK 4320 Query: 1007 GTVTLVCSNPPCETHETGTTNTATTTVVANLGG-HPQPTQVQFVCDRQEAAASLVTSTVG 1065 T T V P TGT TTT VA + HP T + TSTV Sbjct: 4321 STATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSST-----------PETTHTSTVL 4369 Query: 1066 QQNGSVVRVCSNPPCETHETGTT--NTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 + R S+ + GTT T T + G + P T T T T Sbjct: 4370 TTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTT 4429 Query: 1124 MSSVGANHQRDARRACAAGTPAVI-------RISVATGALEAAQGSKSQCQTRQTSATST 1176 ++ A+ A + GT ++ ++V TG+ A +++ T S T+T Sbjct: 4430 TATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTAT 4489 Query: 1177 TMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHA 1236 T TV ++ A S+ P ++ P RS A ++P+ A Sbjct: 4490 TPTVTSSKATPSSSPGTATAL---PALRSTA-------------TTPT-----------A 4522 Query: 1237 VSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCET 1296 S A+ SS+G R+ S T T TA + PS+T P Sbjct: 4523 TSFTAIPSSSLGTTWTRL------------SQTTTPTATMSTATPSST-------PETVH 4563 Query: 1297 HETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRP 1356 T T TATT+ A + S+ P H T T TT + + P PP Sbjct: 4564 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS 4623 Query: 1357 CETHQTTSTGTTMSVSV-GALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQR 1415 T TT+T TT +V + +P T + R + + + T A ++ P + + Sbjct: 4624 TTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTT--------TTTTVATGSMATPSSSTQ 4675 Query: 1416 VCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVEST-QGDSVNITSSSAITT 1474 PP T T TT TAT T+N SS P +T S TSSS+ T Sbjct: 4676 TSGTPPSLT-TTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRT 4734 Query: 1475 TVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534 ++TL +T T+ST +P P Q P + + T+ E+ Sbjct: 4735 --ATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHT 4792 Query: 1535 LSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE--LM 1592 S T +ST PSS + T T S S P ++ Sbjct: 4793 -STVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWIL 4851 Query: 1593 AEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEP 1652 E T ++ TG T A A++ + + A + A + + + Sbjct: 4852 TEPSTIATVMVPTGST---------ATASSTLGTAHTPKVVTTMATMPTATASTVPSSST 4902 Query: 1653 MDTSEAAATV 1662 + T+ A + Sbjct: 4903 VGTTRTPAVL 4912 Score = 163 bits (413), Expect = 1e-39 Identities = 366/1547 (23%), Positives = 528/1547 (34%), Gaps = 217/1547 (14%) Query: 365 PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANP 424 P V T + + G+VAT S +P T T + TP+ P P Sbjct: 3274 PETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP 3333 Query: 425 PKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT---VPGSSISVPTAARTQ 481 P + P T+ G T+ P + P T T+ T GS + ++ +T Sbjct: 3334 -----PVWISTTTTPTTR-GSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS 3387 Query: 482 GVPAVLKVTGPQAT-TGTPLVTMRPASQAGKAPV-----TVTSLPAGVRMVVPTQSAQGT 535 G P L T T TG+ T P+S G P+ T + PA V SA GT Sbjct: 3388 GTPPSLTTTATTITATGS---TTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGT 3444 Query: 536 VIGSSPQMSGMAALAAAAAATQKIPPSSAPTV----LSVPAG----TTIVKTMAVTPGTT 587 +P + A + +PPSS TV S +G T I + VT T Sbjct: 3445 T--HTPPVPN----TTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTP 3498 Query: 588 TLPATVKVASSPVMVS-NPATRMLK--------TAAAQVGTSVSSATNTSTRPIITVHKS 638 + S+P + S +P++R + T GTS ++AT T ++ + Sbjct: 3499 AATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLP 3558 Query: 639 GTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSA----LISNLGKVMSVVQTKPVQT 694 + T A VVTT + +PG S SN+ V +P+ Sbjct: 3559 SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGL 3618 Query: 695 SAVTGQASTG-PVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIIT---TTQASGAGTKPT 749 QA G P+ ++ Q + L G + + GK G P+ Sbjct: 3619 EC-RAQAQPGVPLRELGQVVECSLDFGLVCRNREQV-GKFKMCFNYEIRVFCCNYGHCPS 3676 Query: 750 ILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITII-----TTKVM 804 SS + ++ PGTT I+ + +A T+ +TG T++P T I TT + Sbjct: 3677 TPATSSTATPSSTPGTTWILTKLTTTATTTE--STGSTATPSSTPGTTWILTEPSTTATV 3734 Query: 805 TSGTGAPAKIITAVPKIATGHGQQGVTQVVL---KGAP-GQPGTILRTVPMGGVRLVTPV 860 T TG+ A + T H T + K P PGT +P TP Sbjct: 3735 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGT-ATALPALRSTATTPT 3793 Query: 861 TVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLS 920 S ++L GTT T T T + S A +A +T +TT T + Sbjct: 3794 ATSFTAIPSSSL---GTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRAT 3850 Query: 921 SQVINPTAITVSAAQT---TLTAAGGLTTP-----TITMQPVSQPTQVTLITAPSGVEAQ 972 V P++ +A T T T G TP T PV T T T+ S V Sbjct: 3851 GSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTV--- 3907 Query: 973 PVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPP--CETHETGTTNTAT 1030 P S+ + T T T + P + T PP T T T +T Sbjct: 3908 ----TPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGST 3963 Query: 1031 TTVVANLGGHPQPTQVQFVCDRQEAAASLVT--STVGQQNGSVVRVCSNPPCETH----- 1083 T + G P P + A +S VT S +G + V N TH Sbjct: 3964 TNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV---PNTTATTHGRSLS 4020 Query: 1084 --ETGTTNTA-TTATSNMAG-------QHGCSNPPCETHETGTTNTATTAMSSVGANHQR 1133 T TA T+ATS G G S+ P T TGTT +T A+SS + R Sbjct: 4021 PSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT--TGTTQHSTPALSSPHPS-SR 4077 Query: 1134 DARRACAAGTPAVIRISVATGALEAAQGSKSQCQT----RQTSATSTTMTVMATGAPCS- 1188 + GT + + A SK++ T TSA TT+ C+ Sbjct: 4078 TTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAW 4137 Query: 1189 ------AGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAM 1242 + P+ GPS GG + S +R + ++ + P G A + + Sbjct: 4138 SEWLDYSYPMPGPS-----GGDFDTY-------SNIRAAGGAVCEQPLGLECRAQAQPGV 4185 Query: 1243 TRSSVG------------------AGEPRMA------------PVCESLQGGS----PST 1268 +G G+ +M C S S PS+ Sbjct: 4186 PLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSS 4245 Query: 1269 TVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNAGSAQRVCSNPP 1321 T T + L +AT T + + GT T+ ATT A S++ S+ P Sbjct: 4246 TPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSP 4305 Query: 1322 -----------CETHETGTTHTATTATSNGGTGQ-PEGGQQPPAG----RPCETHQTTST 1365 T T T+ T +++ G TG PE P A P T +TT T Sbjct: 4306 RTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHT 4365 Query: 1366 GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425 T ++ A ATSS T S + A T A PT S P Sbjct: 4366 STVLTTK--ATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWI 4423 Query: 1426 ETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT 1485 T T TATT S S+ P + + + + +T + T T SST A T Sbjct: 4424 LTELTTTATTTASTGST--ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGT 4481 Query: 1486 ---TVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTAL---------MGESAE 1533 + T +TP S P SPG LP + + TA +G + Sbjct: 4482 PHVSTTATTPTVTSSKATPSS---SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT 4538 Query: 1534 VLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMA 1593 LS + TP ST PSS E+ ++ V T T S S P Sbjct: 4539 RLSQTTTP-----TATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHT 4593 Query: 1594 EAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPM 1653 TTT T TP TA + T + ++ GT Sbjct: 4594 TKVPTTTTTGFTA-TPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTH-- 4650 Query: 1654 DTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLP 1713 T T G ++ Q + P LT + P Sbjct: 4651 TARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGT---TP 4707 Query: 1714 TEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNT 1760 + + + A S + + +T+ +L STAT+S A S T Sbjct: 4708 ITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFT 4754 Score = 161 bits (407), Expect = 7e-39 Identities = 300/1274 (23%), Positives = 448/1274 (35%), Gaps = 180/1274 (14%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 P+T AT+++ TP+ P + AA A T + + P AP P T+ Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTT-AATTTATTGSTAIPSST-PGTAPPPKVLTSTA 3032 Query: 463 VLPTVPGSSISVPTAARTQGVPAVLKVTGPQ--ATTGTPLVTMRPASQAGKAPVTVTSLP 520 PT S + ++ RT VL T + AT+ TP+ + G P T+ Sbjct: 3033 TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSF-TLGTTGTLPEQTTTPM 3091 Query: 521 AGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580 A + + P+ S+P+ + + + A T + SS T S P GTT + T Sbjct: 3092 ATMSTIHPS---------STPETTHTSTVLTTKATTTR-ATSSMSTPSSTP-GTTWILTE 3140 Query: 581 AVTPGTTTLPA--TVKVASSP---VMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635 T TTT T +S+P +++ P+T TA V T S+AT +STR Sbjct: 3141 LTTAATTTAATGPTATPSSTPGTTWILTEPST----TATVTVPTG-STATASSTRA---- 3191 Query: 636 HKSGTVTVAQQAQVVTTVVG---------GVTKTITLVKSPISVPGGSALISNLGKVMSV 686 +GT+ V TV+ G + ++S + P +++ + + Sbjct: 3192 -TAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGT 3250 Query: 687 VQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGT 746 T+ QT+ T ST + +T T T A G T +T + Sbjct: 3251 AWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTK 3310 Query: 747 KPTILGISSVSPSTTKPGTT-TIIKTIPMSAIITQAGATGVTSS-PGIKSPITIITTKVM 804 PT + ++ PGT T I + T G+T SS PG T++TT Sbjct: 3311 VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT 3370 Query: 805 TSGTGAPAKIITAVPKIATGHG-QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVS 863 T TG+ A ++ T T + G+ P + T P+ V T T + Sbjct: 3371 TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA 3430 Query: 864 AVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQV 923 A VT GTT + T T H S ++P T + +S + Sbjct: 3431 ATSSTVTPSSALGTTHTPPVPNTTATT---------HGRSLPPSSPHTVRTAWTSATSGI 3481 Query: 924 INPTAITVSAAQTTLTAAGGLTTPTITMQPVS--QPTQVTLITAPSGVEAQPVHDLPVSI 981 + T IT + T+ T A +T + +S P+ T + PS P H S Sbjct: 3482 LGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSR 3541 Query: 982 LASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHE------------TGTTNTA 1029 + T T T T+ S TV P C E G +T Sbjct: 3542 TTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 3601 Query: 1030 TTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQ---------------QNGSVVRV 1074 + A QP ++ R +A + +GQ + ++ Sbjct: 3602 SNIRAAGGAVCEQPLGLEC---RAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKM 3658 Query: 1075 CSNPPCET------HETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVG 1128 C N H T T++TAT + S P T T TATT S+ Sbjct: 3659 CFNYEIRVFCCNYGHCPSTPATSSTATPS-------STPGTTWILTKLTTTATTTESTGS 3711 Query: 1129 ANHQRDARRACAAGTPAVI-------RISVATGALEAAQGSKSQCQTRQTSATSTTMTVM 1181 A + GT ++ ++V TG+ A +++ T S T+TT TV Sbjct: 3712 T-----ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVT 3766 Query: 1182 ATGAPCSAGPLLGPSMARE-PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTA 1240 ++ A P P A P RS A ++P+ A S Sbjct: 3767 SS----KATPFSSPGTATALPALRSTA-------------TTPT-----------ATSFT 3798 Query: 1241 AMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETG 1300 A+ SS+G R+ S T T TA + PS+T P T Sbjct: 3799 AIPSSSLGTTWTRL------------SQTTTPTATMSTATPSST-------PETAHTSTV 3839 Query: 1301 TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH 1360 T TATT+ A + S+ P H T T TT + + P + PP T Sbjct: 3840 LTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTT 3899 Query: 1361 QTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNP 1420 TTS T SV T T + VA TP + T S Sbjct: 3900 PTTSGSTVTPSSVPGTTHTPTVLTTTTTT---VATGSMATPSSSTQ----------TSGT 3946 Query: 1421 PCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVEST-QGDSVNITSSSAITTTVSST 1479 P T TT TAT T+N SS P +T S +T SSA+ TT + Sbjct: 3947 PPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 4006 Query: 1480 LTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQ-SASTALMGESAEVLSAS 1538 + TT T PS P + L + + S T+ + + Sbjct: 4007 VPN--TTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 4064 Query: 1539 QTPELPAAVDLSSTGE--PSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQ 1596 TP L + S T E PS G + G + P+++ L LP + Sbjct: 4065 STPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTL-LPS---SPTS 4120 Query: 1597 AGTTTLMVTGLTPE 1610 A TT++ TG P+ Sbjct: 4121 APITTVVTTGCEPQ 4134 Score = 159 bits (401), Expect = 3e-38 Identities = 370/1575 (23%), Positives = 540/1575 (34%), Gaps = 258/1575 (16%) Query: 365 PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANP 424 P A V T + + G+VAT S +P T T + TP+ P P Sbjct: 2017 PETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP 2076 Query: 425 PKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT---VPGSSISVPTAARTQ 481 P + P T+ G T+ P + P T T+ T GS + ++ +T Sbjct: 2077 -----PVWISTTTTPTTR-GSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS 2130 Query: 482 GVPAVLKVTGPQAT-TGTPLVTMRPASQAGKAPV-----TVTSLPAGVRMVVPTQSAQGT 535 G P L T T TG+ T P+S G P+ T + PA V SA GT Sbjct: 2131 GTPPSLTTTATTITATGS---TTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGT 2187 Query: 536 VIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT--IVKTMAVTPGTT----TL 589 + P + MA + +PPSS TV + T I+ T +T +T TL Sbjct: 2188 T-HTPPVPNTMATTHG-----RSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTL 2241 Query: 590 PATVKVA--SSPVMVS-NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQ 646 AT S+P + S +P++R ++ + GT+ T ++R T S T T Sbjct: 2242 AATTGTTQHSTPALSSPHPSSRTTESPPSP-GTTTPGHTTATSRTTATATPSKTRTSTLL 2300 Query: 647 AQVVTTVVGGVTKTITLVKSP-----------ISVPGGSA----LISNLGKVMSVVQTKP 691 T+ +T +T+ P +PG S SN+ V +P Sbjct: 2301 PSSPTS--APITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP 2358 Query: 692 VQTSAVTGQASTG-PVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIIT---TTQASGAGT 746 + QA G P+ ++ Q + L G + + GK G Sbjct: 2359 LGLEC-RAQAQPGVPLRELGQVVECSLDFGLVCRNREQV-GKFKMCFNYEIRVFCCNYGH 2416 Query: 747 KPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITII-----TT 801 P+ SS + ++ PGTT I+ + +A T+ +TG T++P T I TT Sbjct: 2417 CPSTPATSSTAMPSSTPGTTWILTELTTTATTTE--STGSTATPSSTPGTTWILTEPSTT 2474 Query: 802 KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVT 861 +T TG+ A + T H T + + P +P T Sbjct: 2475 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP-------------FSSPGT 2521 Query: 862 VSAVKPAVTTLVVKGTTGVTTL-GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLS 920 +A+ +T T T + + GT T L+ + + S ATP +T T+ T Sbjct: 2522 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHT-- 2579 Query: 921 SQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQP------V 974 S V+ TA TT A G + TP+ T P + T L T +G A P Sbjct: 2580 STVLTTTA-------TTTGATGSVATPSST--PGTAHTTKVLTTTTTGFTATPSSSPGTA 2630 Query: 975 HDLPV--SILASPTTE------------------QPTATVTIADSGQGDVQPGTVTLVCS 1014 LPV S +PTT T T T+A P + T Sbjct: 2631 RTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM--ATPSSSTQTSG 2688 Query: 1015 NPPCETHETGTTNTA---TTTVVANLGGHPQPTQVQFVCDRQEAAASLVT--STVGQQNG 1069 PP T T TT TA TT + G P P + A +S VT S +G + Sbjct: 2689 TPPSLT-TTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHT 2747 Query: 1070 SVVRVCSNPPCETH-------ETGTTNTA-TTATSNMAG-------QHGCSNPPCETHET 1114 V N TH T TA T+ATS G G S+ P T T Sbjct: 2748 PPV---PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT--T 2802 Query: 1115 GTTNTATTAMSSV-GANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT----R 1169 GTT +T A+SS ++ ++ + TP R + T A A SK++ T Sbjct: 2803 GTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTA--TATPSKTRTSTLLPSS 2860 Query: 1170 QTSATSTTMTVMATGAPCS-------AGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSS 1222 TSA TT+ M C+ + P+ GPS GG + S +R + Sbjct: 2861 PTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPS-----GGDFDTY-------SNIRAAG 2908 Query: 1223 PSIKDLPAGRHSHAVSTAAMTRSSVG---AGEPRMAPVCESLQGGSPSTTVTVTALEALL 1279 ++ + P G A + + +G VC + + + Sbjct: 2909 GAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 2968 Query: 1280 C-----PSATVTQVCSNPPCETHET-----GTTNTATTSNAGSAQRVCSNPPCETHETGT 1329 C PS T + P T TT TT+ GS S P Sbjct: 2969 CNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVL 3028 Query: 1330 THTATTATSNGGTGQPEGGQQPPAGRPCETHQTT-STGT------TMSVSVGALLPDATS 1382 T TATT T+ + P T T ST T + ++ LP+ T+ Sbjct: 3029 TSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTT 3088 Query: 1383 SHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSS 1442 + S + ++ P T T L T R S+ + GTT T +T+ ++ Sbjct: 3089 TPMATMSTIHPSSTPETT-HTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3147 Query: 1443 NQDPPPAASDQGEVEST-----QGDSVNITSSSAITTTVSSTLTRA----VTTVTQSTPV 1493 P A+ +T + +T + T T SST A V T T +TP Sbjct: 3148 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3207 Query: 1494 PGPSVPPPEELQVSPGPRQQLPPRQLLQSASTAL---------MGESAEVLSASQTPELP 1544 S P SPG LP + + TA +G + LS + TP Sbjct: 3208 VISSRATPSS---SPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTP--- 3261 Query: 1545 AAVDLSSTGEPSSGQESAGSAVV---------ATVVVQPPPPTQSEVDQLSLPQELMAEA 1595 ST PSS E+ ++ V AT V P T +P Sbjct: 3262 --TATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 3319 Query: 1596 QA-----------------GTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAV 1638 A TTT G T ++ A T A A Sbjct: 3320 TATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT 3379 Query: 1639 LQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQ 1698 ++ Q +G P + A T+T G + T IP VLT Sbjct: 3380 PSSSTQT---SGTPPSLTTTATTITAT--GSTTNPSSTPGTTPIPPVLTTTATTPAATSS 3434 Query: 1699 QLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPS 1758 + + A H P N A L + P TV ++AT + + Sbjct: 3435 TVTPSSALGTTHTPPVP--------NTTATTHG--RSLPPSSPHTVRTAWTSATSGILGT 3484 Query: 1759 NTFVAPQPVVVASPA 1773 P V +PA Sbjct: 3485 THITEPSTVTSHTPA 3499 Score = 146 bits (369), Expect = 2e-34 Identities = 319/1363 (23%), Positives = 459/1363 (33%), Gaps = 234/1363 (17%) Query: 465 PTVPGSSISVPTAARTQGVPAVL-KVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGV 523 P+ P +S S T + T G +L K+T TT + T P+S G + Sbjct: 3675 PSTPATS-STATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWI--------- 3724 Query: 524 RMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVT 583 + P+ +A TV +G A A++ AT P S T + P T+ T + Sbjct: 3725 -LTEPSTTATVTV------PTGSTATASSTQATAGTPHVS--TTATTPTVTSSKATPFSS 3775 Query: 584 PGTTT-LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVS--SATNTSTRPIITVHKSGT 640 PGT T LPA A++P AT ++ +GT+ + S T T T + T S T Sbjct: 3776 PGTATALPALRSTATTPT-----ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSST 3830 Query: 641 VTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ 700 A + V+TT T+ V +P S PG T V T+ TG Sbjct: 3831 PETAHTSTVLTTTAT-TTRATGSVATPSSTPG-------------TAHTTKVPTTTTTGF 3876 Query: 701 ASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPST 760 T + P A T P I+TT T PT G S+V+PS+ Sbjct: 3877 TVT-------PSSSPGTART-----------PPVWISTT------TTPTTSG-STVTPSS 3911 Query: 761 TKPGTT--TIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818 PGTT + T + + T + AT +S+ +P ++ITT + TG+ Sbjct: 3912 V-PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTT------ 3964 Query: 819 PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT 878 P + T P+ V T T +A VT GTT Sbjct: 3965 ----------------------NPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTT 4002 Query: 879 GVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTL 938 + T T H S S ++P T + +S + T IT + T+ Sbjct: 4003 HTPPVPNTTATT---------HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSH 4053 Query: 939 TAAG--GLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTI 996 T A G T + P+ T + PS P H S + T T T T+ Sbjct: 4054 TPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTL 4113 Query: 997 ADSGQGDVQPGTVTLVCSNPPCETHE------------TGTTNTATTTVVANLGGHPQPT 1044 S TV P C E G +T + A QP Sbjct: 4114 LPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPL 4173 Query: 1045 QVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGC 1104 ++ Q V + + VC N + G N + C Sbjct: 4174 GLECRAQAQPGVPLGELGQVVECSLDFGLVCRN----REQVGKFKMC----FNYEIRVFC 4225 Query: 1105 SNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKS 1164 N H T T++TAM S GT ++ T A+ GS Sbjct: 4226 CN---YGHCPSTPATSSTAMPS------------STPGTTWILTELTTTATTTASTGS-- 4268 Query: 1165 QCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPS 1224 T+T + T P P + P A A SS R ++ Sbjct: 4269 ---------TATPSSTPGTAPP--------PKVLTSPATTPTATSSKATSSSSPRTATTL 4311 Query: 1225 IKDLPAGRHSHAVSTAAMTRSSVGA----GEPRMAPVCESLQGGSPSTTVTVTALEALLC 1280 S A S + S++G E PV ++ PS+T T +L Sbjct: 4312 PVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVA-TMSTIHPSSTPETTHTSTVLT 4370 Query: 1281 PSATVTQVCSNPPCETHETGTT------NTATTSNA--GSAQRVCSNPPCETHETGTTHT 1332 AT T+ S+ + GTT TA T+ A G S P T T T Sbjct: 4371 TKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTT 4430 Query: 1333 ATTATSNGGTGQPEGG-------QQP--------PAGRPCETHQTTSTGTTMSVSVGALL 1377 ATT S G T P +P P G T +T T VS A Sbjct: 4431 ATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT 4490 Query: 1378 PDATSSHRTVESGLEVAAA-PSVTPQAGTALLAPFPTQRVCSNPPCETH-ETGTTHTATT 1435 P TSS T S A A P++ A T F S T TT TAT Sbjct: 4491 PTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM 4550 Query: 1436 VTSNMSSNQDPPPAASDQGEVESTQGDSVNI-----TSSSAITTTVSSTLTRAVTTVTQS 1490 T+ SS + ++ +T G + ++ T +A TT V +T T T S Sbjct: 4551 STATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 4610 Query: 1491 TPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMG--ESAEVLSASQTPELPAAVD 1548 + PG ++ PP + + P P +++ G +A VL+ + T V Sbjct: 4611 S--PGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTT-----TVA 4663 Query: 1549 LSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLT 1608 S PSS +++G+ T T S + S P GTT + LT Sbjct: 4664 TGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTP---------GTTPITPV-LT 4713 Query: 1609 PEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELG 1668 A + A +++ A L + A T P T TV Sbjct: 4714 STATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTT 4773 Query: 1669 HLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAI 1728 +S ++T T L + + A P+ +L I Sbjct: 4774 PMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTA------------TPSSTLGTTRI 4821 Query: 1729 ESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVAS 1771 L EL T +T A STAT S P T++ +P +A+ Sbjct: 4822 ----LTELT-TTATTTAATGSTATLSSTPGTTWILTEPSTIAT 4859 Score = 144 bits (363), Expect = 9e-34 Identities = 291/1345 (21%), Positives = 444/1345 (33%), Gaps = 202/1345 (15%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 P ++ T P+P + P + + A A + T TLLP + + P TT + Sbjct: 2258 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS---TLLPSSPTSAPITTVVT 2314 Query: 463 V-----------------LPTVPGSSISVPTAARTQGVPAVLKVTG----PQATTGTPL- 500 + +P G + R G + G QA G PL Sbjct: 2315 MGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLR 2374 Query: 501 -------------VTMRPASQAGKAPVTVT--------------SLPAGVRMVVPTQS-- 531 + R Q GK + S PA +P+ + Sbjct: 2375 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPG 2434 Query: 532 -----AQGTVIGSSPQMSGMAALAAAAAATQKI--PPSSAPTVLSVPAGTTIVKTMAVTP 584 + T ++ + +G A ++ T I PS+ TV +VP G+T T + T Sbjct: 2435 TTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV-TVPTGSTA--TASSTQ 2491 Query: 585 GTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVA 644 T P A++P + S+ AT A ++ S T T T S ++ Sbjct: 2492 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 2551 Query: 645 QQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG 704 TT T T P S P V T V T+ T +TG Sbjct: 2552 WTRLSQTTTPTATMSTAT----PSSTP-------------ETVHTSTVLTTTATTTGATG 2594 Query: 705 PVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPG 764 V T G A T L T+ TT T T +S GT T+ S + + T G Sbjct: 2595 SVATPSSTPGT--AHTTKVLTTT-----TTGFTATPSSSPGTARTLPVWISTTTTPTTRG 2647 Query: 765 TTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATG 824 +T +IP G T +P T++TT T TG+ A ++ T Sbjct: 2648 STVTPSSIP-----------GTTHTP------TVLTTTTTTVATGSMATPSSSTQTSGTP 2690 Query: 825 HG-QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883 T + G+ P + T P+ V T T +A VT GTT + Sbjct: 2691 PSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 2750 Query: 884 GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG- 942 T T H S S ++P T + +S + T IT + T+ T A Sbjct: 2751 PNTTATT---------HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 2801 Query: 943 -GLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T + P+ T + PS P H S + T T T T+ S Sbjct: 2802 TGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSP 2861 Query: 1002 GDVQPGTVTLVCSNPPCETHE------------TGTTNTATTTVVANLGGHPQPTQVQFV 1049 TV + P C E G +T + A QP ++ Sbjct: 2862 TSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECR 2921 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPP----------------CETHETGTTNTATT 1093 Q V + + VC N C + + AT+ Sbjct: 2922 AQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS 2981 Query: 1094 ATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVAT 1153 +T+ + G + E T T TATT +++ ++ GT ++ +T Sbjct: 2982 STATPSSTPGTTWILTE-QTTAATTTATTGSTAIPSS---------TPGTAPPPKVLTST 3031 Query: 1154 GALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAP 1213 A SK+ + + T+TT+ V+ + A S P + G Q Sbjct: 3032 ATTPTATSSKA--TSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTT 3089 Query: 1214 LSSKVRLSSPSIKDLPAGRHSHAVST--AAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 + + PS P H+ V T A TR++ P P + + T Sbjct: 3090 PMATMSTIHPS--STPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3147 Query: 1272 VTALEALLCPSAT--VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGT 1329 A PS+T T + + P T T T T +T+ A S + Sbjct: 3148 TAATGPTATPSSTPGTTWILTEP--STTATVTVPTGSTATASSTRATAGTLKV------L 3199 Query: 1330 THTATTATSNGGTGQPEGGQQPPAGRPC-ETHQTTSTGTTMSVSVGALLPDATS--SHRT 1386 T TATT T P P + TT T T+++ + L A + S T Sbjct: 3200 TSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3259 Query: 1387 VESGLEVAAAPSVTPQ---AGTALLAPFPTQRVCSNPPCETHETGTTHTA---TTVTSNM 1440 + A PS TP+ T L T R + + GT HT TT T+ Sbjct: 3260 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 3319 Query: 1441 SSNQD-------PPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPV 1493 ++ PP +T+G +V T SS TT ++T V T T +T Sbjct: 3320 TATPSSSPGTALTPPVWISTTTTPTTRGSTV--TPSSIPGTTHTAT----VLTTTTTTVA 3373 Query: 1494 PGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTG 1553 G P Q S PP + + G + S T +P + ++T Sbjct: 3374 TGSMATPSSSTQTS-----GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATT 3428 Query: 1554 EPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSL----PQELMAEAQAGTTTLMVTGLTP 1609 ++ S+ + T P P T + SL P + + T+ ++ T Sbjct: 3429 PAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHIT 3488 Query: 1610 EELAVTAAAEAAAQAAATEEAQALA 1634 E VT+ AA + AL+ Sbjct: 3489 EPSTVTSHTPAATTSTTQHSTPALS 3513 Score = 137 bits (344), Expect = 1e-31 Identities = 316/1441 (21%), Positives = 487/1441 (33%), Gaps = 267/1441 (18%) Query: 325 HCAVAINTRLYIWSGRDGYRKAWNNQV---CCKDLWYLETEKPPPPARVQLVRANTNSLE 381 HC V W ++ +N ++ CC D PPP T LE Sbjct: 1570 HCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPP---------TTELE 1620 Query: 382 VSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLT 441 TA T T+ P ++P + AP A+ AV L+ Sbjct: 1621 -----------------------TATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLS 1657 Query: 442 QVGIT------LLPQAAPAPPTTTTIQVLPTVPGSSIS-VPTAARTQGVPAVLKVTGPQA 494 + G+T L A PTT PTVPG + S +PT + G Sbjct: 1658 E-GLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPG------------ 1704 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TTG+ L T RP+ AP T+ + A T S + +P ++ + + A Sbjct: 1705 TTGS-LGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAET 1763 Query: 555 ATQKIPPSSAP-TVLSVPAGTTIVK--------------TMAVTPGTTTLPATVKVAS-- 597 +T + + +P T + GTT + T V G ++ A Sbjct: 1764 STPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGK 1823 Query: 598 ---SPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVV 654 +P + A + + QVG ++ + T ++G + V Sbjct: 1824 MCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGL-TCKNEDQTGRFNMCFNYNVRVLCC 1882 Query: 655 GGV-----TKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ-ASTGPVTQ 708 T + +P S PG + ++ TKP T+ T ST T Sbjct: 1883 DDYSHCPSTPATSSTATPSSTPGTTWIL-----------TKPTTTATTTASTGSTATPTS 1931 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 ++T P K++T+ PT +T+++A+ + + T + ++ + T P T T Sbjct: 1932 TLRTAPP------PKVLTTTATTPT--VTSSKATPSSSPGTATALPALRSTATTP-TATS 1982 Query: 769 IKTIPMSAI---------ITQAGATGVTSSPGIKSPITIITTKVMT---SGTGAPAKIIT 816 + IP S++ T AT T++P +P T T+ V+T + TGA + T Sbjct: 1983 VTPIPSSSLGTTWTRLSQTTTPTATMSTATPS-STPETAHTSTVLTATATTTGATGSVAT 2041 Query: 817 AVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG 876 T H + V G P + T V + T T + VT + G Sbjct: 2042 PSSTPGTAHTTK-VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG 2100 Query: 877 TT-GVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQ 935 TT T L T T TV+T S+ATP ++ T T P ++T +A Sbjct: 2101 TTHTATVLTTTTTTVAT-----------GSMATPSSSTQTSGT-------PPSLTTTA-- 2140 Query: 936 TTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVT 995 TT+TA G T P+ T P + P L T + A P S L TT P T Sbjct: 2141 TTITATGSTTNPSST--PGTTPIPPVLTTTATTPAATSNTVTPSSALG--TTHTPPVPNT 2196 Query: 996 IADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEA 1055 +A T S PP H T TA T+ + + G T+ V A Sbjct: 2197 MA-----------TTHGRSLPPSSPH---TVRTAWTSATSGILGTTHITEPSTVTSHTLA 2242 Query: 1056 AASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETG 1115 A TGTT +T A S+ H + Sbjct: 2243 AT---------------------------TGTTQHSTPALSS-------------PHPSS 2262 Query: 1116 TTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATS 1175 T + + + H R A TP+ R S + + TSA Sbjct: 2263 RTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS-------------TLLPSSPTSAPI 2309 Query: 1176 TTMTVMATGAPCS-------AGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDL 1228 TT+ M C+ + P+ GPS GG + S +R + ++ + Sbjct: 2310 TTVVTMGCEPQCAWSEWLDYSYPMPGPS-----GGDFDTY-------SNIRAAGGAVCEQ 2357 Query: 1229 PAGRHSHAVSTAAMTRSSVG---AGEPRMAPVCESLQGGSP-----STTVTVTALEALLC 1280 P G A + + +G VC + + + + V C Sbjct: 2358 PLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC 2417 Query: 1281 PSATVTQVCSNPPCETHETG-----TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATT 1335 PS T + P T TT TT + GS S P T + TAT Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 2477 Query: 1336 ATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAA 1395 G T Q AG P + T+ T S + P ++ + S Sbjct: 2478 TVPTGSTA-TASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPT 2536 Query: 1396 APSVTPQAGTALLAPF--------PTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPP 1447 A S T ++L + PT + + P T E T HT+T +T+ ++ Sbjct: 2537 ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE--TVHTSTVLTTTATTTGATG 2594 Query: 1448 PAASDQGEVESTQGDSVNITSSSAITTTVSST----LTRAVTTVTQSTPVPGPSVPPPEE 1503 A+ + V T+++ T T SS+ T V T +TP S P Sbjct: 2595 SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSS 2654 Query: 1504 LQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAG 1563 + P P L + +T G A S++QT P ++ ++T ++G + Sbjct: 2655 I-----PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP 2709 Query: 1564 SAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQ 1623 S+ T + PP T + + + + GTT T P A T + Sbjct: 2710 SSTPGTTPI-PPVLTTTATTPAATSSTVTPSSALGTTH---TPPVPNTTATTHGRSLSPS 2765 Query: 1624 AAAT-EEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTI 1682 + T A A L TG T A TQ LS+ + T Sbjct: 2766 SPHTVRTAWTSATSGTLGTTHITEPSTG-TSHTPAATTGTTQHSTPALSSPHPSSRTTES 2824 Query: 1683 P 1683 P Sbjct: 2825 P 2825 Score = 134 bits (337), Expect = 9e-31 Identities = 345/1572 (21%), Positives = 518/1572 (32%), Gaps = 305/1572 (19%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 + T ++ V G+ ATA S + + +TAT+PT V S A P SP A A Sbjct: 3171 STTATVTVPTGSTATASS--TRATAGTLKVLTSTATTPT---VISSRATPSSSPGTATAL 3225 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT-------VPGSSISVPTAARTQGVPAVL 487 PA++ + PT T++ +P+ S + PTA + P+ Sbjct: 3226 PALR------------STATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSST 3273 Query: 488 KVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMV-VPTQSAQG-TVIGSSPQMSG 545 T T T L T ++A + T +S P VPT + G T SS + Sbjct: 3274 PET---VHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA 3330 Query: 546 MAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNP 605 + + T S T S+P GTT T+ T TTT AT +A+ Sbjct: 3331 LTPPVWISTTTTPTTRGSTVTPSSIP-GTTHTATVLTT--TTTTVATGSMATPSSSTQTS 3387 Query: 606 ATRMLKTAAAQVGTSVSSATNTSTRPIIT-----VHKSGTVTVAQQAQVVTTVVGGVTKT 660 T T A T+ S TN S+ P T + + T A + V + G T T Sbjct: 3388 GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHT 3447 Query: 661 ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720 + + + G S S+ V + TSA +G T +T+ PA T Sbjct: 3448 PPVPNTTATTHGRSLPPSSPHTV------RTAWTSATSGILGTTHITEPSTVTSHTPAAT 3501 Query: 721 ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780 TS T +++ S T+ S SP TT PG T Sbjct: 3502 -----TSTTQHSTPALSSPHPSSRTTE------SPPSPGTTTPGHT------------RG 3538 Query: 781 AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG 840 T T++P T +T + +S T AP IT V + TG Q L + Sbjct: 3539 TSRTTATATPS----KTRTSTLLPSSPTSAP---ITTV--VTTGCEPQCAWSEWLDYSYP 3589 Query: 841 QPG-------TILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTS 893 PG T GG P+ + A + ++ V G V + Sbjct: 3590 MPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRN 3649 Query: 894 LAGAG-----------------GHSTS----ASLATPITTLGTIATLSSQVINPTAITVS 932 G GH S +S ATP +T GT L+ + TA T Sbjct: 3650 REQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTK--LTTTATTTE 3707 Query: 933 AAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA 992 + +T T + +TP T +++P+ +T P+G A + +T T Sbjct: 3708 STGSTATPS---STPGTTW-ILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTP 3763 Query: 993 TVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDR 1052 TVT + PGT T + + T TT TAT+ Sbjct: 3764 TVT-SSKATPFSSPGTATALPA-----LRSTATTPTATSFTAI----------------- 3800 Query: 1053 QEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGC----SNPP 1108 ++ + + Q + + P T ET T+T T T+ G S+ P Sbjct: 3801 PSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTP 3860 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQC-- 1166 H T T TT + ++ AR TP V + T + + S Sbjct: 3861 GTAHTTKVPTTTTTGFTVTPSSSPGTAR------TPPVWISTTTTPTTSGSTVTPSSVPG 3914 Query: 1167 QTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIK 1226 T + +TT T +ATG+ + PS + + G P+ + A Sbjct: 3915 TTHTPTVLTTTTTTVATGS------MATPSSSTQTSGTPPSLITTA-------------- 3954 Query: 1227 DLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL------LC 1280 + +T + T S G + PV + +T+ TVT AL Sbjct: 3955 -------TTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 4007 Query: 1281 PSAT-VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSN 1339 P+ T T S P H T T+ TS + + P T T T TT S Sbjct: 4008 PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI-TEPSTGTSHTPAATTGTTQHST 4066 Query: 1340 GGTGQPEGG----QQPPA------GRPCETHQTTSTGTTMSVSVGALLPDATSS---HRT 1386 P + PP+ G T +TT+T T LLP + +S Sbjct: 4067 PALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 4126 Query: 1387 VESGLEVAAA----------------------PSVTPQAGTALLAPFPTQ-RVCSNPPCE 1423 V +G E A ++ G P + R + P Sbjct: 4127 VTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 4186 Query: 1424 THETGTTHTAT----TVTSN--------MSSNQDPPPAASDQGEVESTQGDSVNITSSSA 1471 E G + V N M N + + G ST S SS Sbjct: 4187 LGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 4246 Query: 1472 -----ITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSAS-- 1524 I T +++T T +T + +TP P PP ++ SP + S+S Sbjct: 4247 PGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPR 4306 Query: 1525 -----TALMGESAEVLSASQTP--------------ELPAAVDLSSTGEPSSGQESAGSA 1565 L + + + S TP + V ST PSS E+ ++ Sbjct: 4307 TATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTS 4366 Query: 1566 VVATVVVQPPPPTQSEVDQLSLPQE--LMAEAQAGTTTLMVTGLTP------------EE 1611 V T T S S P ++ E TT TG T E Sbjct: 4367 TVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTE 4426 Query: 1612 LAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLS 1671 L TA A+ + AT + + + + A + T T+ A++T A H+S Sbjct: 4427 LTTTATTTASTGSTATPSSTPGTTWILTEPSTTATV-TVPTGSTATASSTQATAGTPHVS 4485 Query: 1672 AEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESN 1731 T P V + + T + +P + PA+ S Sbjct: 4486 T------TATTPTVTSSK-----------------------ATPSSSPGTATALPALRST 4516 Query: 1732 CLNELAGT---VPS-----TVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTE 1783 A + +PS T L T T + S + P V + L A AT T Sbjct: 4517 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTG 4576 Query: 1784 VANGIESLGVKP 1795 + + P Sbjct: 4577 ATGSVATPSSTP 4588 Score = 133 bits (335), Expect = 2e-30 Identities = 335/1527 (21%), Positives = 496/1527 (32%), Gaps = 257/1527 (16%) Query: 377 TNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPA 436 T + S G+ AT S L + T TAT+PT V S A P SP A A PA Sbjct: 1916 TATTTASTGSTATPTSTLRTAPPPKVLTT--TATTPT---VTSSKATPSSSPGTATALPA 1970 Query: 437 VQPL--TQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV-TGPQ 493 ++ T ++ P + + TT T T P +++S T + T V T Sbjct: 1971 LRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATA 2030 Query: 494 ATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQG-TVIGSSPQMSGMAALAAA 552 TTG P+S G A T VPT + G T SS + + Sbjct: 2031 TTTGATGSVATPSSTPGTAHTTK----------VPTTTTTGFTATPSSSPGTALTPPVWI 2080 Query: 553 AAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKT 612 + T S T S+P GTT T+ T TTT AT +A+ T T Sbjct: 2081 STTTTPTTRGSTVTPSSIP-GTTHTATVLTT--TTTTVATGSMATPSSSTQTSGTPPSLT 2137 Query: 613 AAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPG 672 A T+ S TN S+ P GT + T + T+T P S G Sbjct: 2138 TTATTITATGSTTNPSSTP-------GTTPIPPVLTTTATTPAATSNTVT----PSSALG 2186 Query: 673 GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP 732 T PV + T + P + + + T L T+ +P Sbjct: 2187 -------------TTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 2233 Query: 733 TTIITTTQASGAG-TKPTILGISSVSPST------TKPGTTTIIKTIPMSAIITQAGATG 785 +T+ + T A+ G T+ + +SS PS+ PGTTT T T T Sbjct: 2234 STVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHT-------TATSRTT 2286 Query: 786 VTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPG-- 843 T++P T +T + +S T AP IT V + G Q L + PG Sbjct: 2287 ATATPS----KTRTSTLLPSSPTSAP---ITTV--VTMGCEPQCAWSEWLDYSYPMPGPS 2337 Query: 844 -----TILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAG 898 T GG P+ + A + ++ V G V + G Sbjct: 2338 GGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVG 2397 Query: 899 -----------------GHSTS----ASLATPITTLGTIATLSSQVINPTAITVSAAQTT 937 GH S +S A P +T GT L+ + TA T + +T Sbjct: 2398 KFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTE--LTTTATTTESTGST 2455 Query: 938 LTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIA 997 T + +TP T +++P+ +T P+G A + +T T TVT + Sbjct: 2456 ATPS---STPGTTW-ILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVT-S 2510 Query: 998 DSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 PGT T + + T TT TAT+ ++ Sbjct: 2511 SKATPFSSPGTATALPA-----LRSTATTPTATSFTAI-----------------PSSSL 2548 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGC----SNPPCETHE 1113 + + Q + + P T ET T+T T T+ G G S+ P H Sbjct: 2549 GTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHT 2608 Query: 1114 TGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSK-SQCQTRQTS 1172 T T TT + A + + GT + + ++T +GS + T+ Sbjct: 2609 TKVLTTTTTGFT---------ATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTT 2659 Query: 1173 ATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR 1232 T T +T T + G + PS + + G P+ A Sbjct: 2660 HTPTVLTTTTT--TVATGSMATPSSSTQTSGTPPSLTTTA-------------------- 2697 Query: 1233 HSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL------LCPSAT-V 1285 + +T + T S G + PV + +T+ TVT AL P+ T Sbjct: 2698 -TTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTAT 2756 Query: 1286 TQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQP 1345 T S P H T T+ TS + + P T T T TT S P Sbjct: 2757 THGRSLSPSSPHTVRTAWTSATSGTLGTTHI-TEPSTGTSHTPAATTGTTQHSTPALSSP 2815 Query: 1346 EGG----QQPPA------GRPCETHQTTSTGTTMSVSVGALLPDATSS---HRTVESGLE 1392 + PP+ G T +TT+T T LLP + +S V G E Sbjct: 2816 HPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCE 2875 Query: 1393 VAAA----------------------PSVTPQAGTALLAPFPTQ-RVCSNPPCETHETGT 1429 A ++ G P + R + P E G Sbjct: 2876 PQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQ 2935 Query: 1430 THTAT----TVTSN--------MSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTT-- 1475 + V N M N + + G ST S T SS TT Sbjct: 2936 VVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWI 2995 Query: 1476 -VSSTLTRAVTTVTQSTPVPGP---SVPPPEEL----------------QVSPGPRQQLP 1515 T T T ST +P + PPP+ L SP LP Sbjct: 2996 LTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLP 3055 Query: 1516 PRQLLQSASTALMGESAEVLSASQTPELP----AAVDLSSTGEPSSGQESAGSAVVATVV 1571 + STA + T LP + ST PSS E+ ++ V T Sbjct: 3056 VLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTK 3115 Query: 1572 VQPPPPTQSEVDQLSLPQE--LMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEE 1629 T S S P ++ E TT TG T + + + T Sbjct: 3116 ATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTAT 3175 Query: 1630 AQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQ 1689 ++ +A GT + + ++ TV + + G AT +P + + Sbjct: 3176 VTVPTGSTATASSTRATAGTLKVLTSTATTPTVISS---RATPSSSPGTATALPALRSTA 3232 Query: 1690 EL-----AALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTV 1744 + L A + PT ++ A + P E+ + + T +T Sbjct: 3233 TTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTP--ETVHTSTVLTTTTTTT 3290 Query: 1745 ALLPSTATESLAPSNTFVAPQPVVVAS 1771 S AT S P P + Sbjct: 3291 RATGSVATPSSTPGTAHTTKVPTTTTT 3317 Score = 131 bits (329), Expect = 8e-30 Identities = 209/828 (25%), Positives = 309/828 (37%), Gaps = 133/828 (16%) Query: 590 PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQV 649 P+T +S+ + S P T + T T+ +S +T+T S T A +V Sbjct: 4232 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTAT-------PSSTPGTAPPPKV 4284 Query: 650 VTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI 709 +T SP + P ++ + T PV TS T +T VT I Sbjct: 4285 LT--------------SPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATS-VTPI 4329 Query: 710 ----IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP--TILGISSVSPSTTKP 763 + T G LP T + T + P++ TT S T T SS S ++ P Sbjct: 4330 PSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTP 4389 Query: 764 GTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIAT 823 GTT I+ + +A T ATG T++P T I T++ T+ T + TA P Sbjct: 4390 GTTWILTELTTAA--TTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS--- 4444 Query: 824 GHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883 G T ++ + P T+ TVP G + +A P V+T T Sbjct: 4445 --STPGTTWILTE--PSTTATV--TVPTGSTATASSTQATAGTPHVST--------TATT 4490 Query: 884 GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGG 943 TVT + +T S+S AT + L + AT + + TAI S+ TT T Sbjct: 4491 PTVTSSKATP-------SSSPGTATALPALRSTAT-TPTATSFTAIPSSSLGTTWTRLSQ 4542 Query: 944 LTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGD 1003 TTPT TM TA + VH V + A+ TT T +V S Sbjct: 4543 TTTPTATMS-----------TATPSSTPETVHTSTV-LTATATTTGATGSVATPSS---- 4586 Query: 1004 VQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 PGT H T T TT A P V + + T+T Sbjct: 4587 -TPGT-----------AHTTKVPTTTTTGFTATPSSSPGTALTPPV---WISTTTTPTTT 4631 Query: 1064 VGQQNGSVVRVCSNP-PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATT 1122 +GS V S P T TT T T AT +MA P T +GT + TT Sbjct: 4632 TPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMA------TPSSSTQTSGTPPSLTT 4685 Query: 1123 AMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMA 1182 +++ A + GT + + +T AA SK+ + + T+TT+ V+ Sbjct: 4686 TATTITATGS-TTNPSSTPGTTPITPVLTSTATTPAATSSKA--TSSSSPRTATTLPVLT 4742 Query: 1183 TGAPCSAGPLLG--PSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAV--S 1238 + A S PS PA P+S+ +S+ P H+ V + Sbjct: 4743 STATKSTATSFTPIPSSTLWTTWTVPA-QTTTPMST---MSTIHTSSTPETTHTSTVLTT 4798 Query: 1239 TAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHE 1298 TA MTR++ +PS+T+ T + L +AT T Sbjct: 4799 TATMTRATNST--------------ATPSSTLGTTRILTELTTTATTT------------ 4832 Query: 1299 TGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCE 1358 T +TAT S+ + + P T + TA+S GT A P Sbjct: 4833 AATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTA 4892 Query: 1359 THQTTSTGTTMSVS-VGALLPDA--TSSHRTVESGLEVAAAPSVTPQA 1403 T T + +T+ + A+LP + T S TV S + P+ P + Sbjct: 4893 TASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSS 4940 Score = 128 bits (322), Expect = 5e-29 Identities = 257/1083 (23%), Positives = 380/1083 (35%), Gaps = 153/1083 (14%) Query: 518 SLPAGVRMVVPTQSAQGTVIGSSPQMSGM--AALAAAAAATQKIPPSSAPTVLSVPAGTT 575 S PA P+ + T I + P + A+ + A T + + P VL+ A T Sbjct: 1890 STPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTP 1949 Query: 576 IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVS--SATNTSTRPII 633 V + TP ++ AT A + AT + ++ +GT+ + S T T T + Sbjct: 1950 TVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMS 2009 Query: 634 TVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQ 693 T S T A + V+T T T T ++ P + ++ KV + T Sbjct: 2010 TATPSSTPETAHTSTVLT-----ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTA 2064 Query: 694 T-SAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILG 752 T S+ G A T PV I T P G+ + + T + TT + T Sbjct: 2065 TPSSSPGTALTPPV-WISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATP 2123 Query: 753 ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPA 812 SS S T P TT TI ATG T++P T I + T+ T A Sbjct: 2124 SSSTQTSGTPPSLTTTATTIT---------ATGSTTNPSSTPGTTPIPPVLTTTATTPAA 2174 Query: 813 KIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVT-- 870 T P A G P P T+ T R + P + V+ A T Sbjct: 2175 TSNTVTPSSALG----------TTHTPPVPNTMATT----HGRSLPPSSPHTVRTAWTSA 2220 Query: 871 TLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAIT 930 T + GTT +T TVT + G HST A L++P + T + S T Sbjct: 2221 TSGILGTTHITEPSTVTSHTLAATTGTTQHSTPA-LSSPHPSSRTTESPPSPGTTTPGHT 2279 Query: 931 VSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS-GVEAQPVHD--LPVSILASPTT 987 + ++TT TA T T T+ P S PT + T + G E Q L S + Sbjct: 2280 TATSRTTATATPS-KTRTSTLLP-SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPS 2337 Query: 988 EQPTATVTIADSGQGDVQPGTVTLVC---SNPPCETHETGTTNTATTTVVANLGGHPQPT 1044 T + + G V + L C + P E G + Sbjct: 2338 GGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECS-------------L 2384 Query: 1045 QVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGC 1104 VC +E N + C N H T T++TA + Sbjct: 2385 DFGLVCRNREQVGKFKMCF----NYEIRVFCCN---YGHCPSTPATSSTAMPS------- 2430 Query: 1105 SNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVI-------RISVATGALE 1157 S P T T TATT S+ A + GT ++ ++V TG+ Sbjct: 2431 STPGTTWILTELTTTATTTESTGST-----ATPSSTPGTTWILTEPSTTATVTVPTGSTA 2485 Query: 1158 AAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE-PGGRSPAFVQLAPLSS 1216 A +++ T S T+TT TV ++ A P P A P RS A Sbjct: 2486 TASSTQATAGTPHVSTTATTPTVTSS----KATPFSSPGTATALPALRSTA--------- 2532 Query: 1217 KVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV---CESLQGGSPSTTVTVT 1273 ++P+ A S A+ SS+G R++ ++ +PS+T Sbjct: 2533 ----TTPT-----------ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETV 2577 Query: 1274 ALEALLCPSATVTQVCSNPPCETHETGTTNTA---TTSNAGSAQRVCSNPPCETHETGTT 1330 +L +AT T + + GT +T TT+ G S+P GT Sbjct: 2578 HTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSP-------GTA 2630 Query: 1331 HTATTATSNGGTGQPEGGQQPPAGRPCETH-QTTSTGTTMSVSVGALLPDATSSHRTVES 1389 T S T G P+ P TH T T TT +V+ G++ AT S T S Sbjct: 2631 RTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM---ATPSSSTQTS 2687 Query: 1390 G---------LEVAAAPSVTPQAGTALLAPFP--------TQRVCSNPPCETHETGTTHT 1432 G + A S T + T P P T S+ + GTTHT Sbjct: 2688 GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHT 2747 Query: 1433 A----TTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVT 1488 TT T++ S P +T G ++ T + +T S T T Sbjct: 2748 PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSG-TLGTTHITEPSTGTSHTPAATTGTTQ 2806 Query: 1489 QSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVD 1548 STP P + P P P S +TA S + +++ P P + Sbjct: 2807 HSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPS-KTRTSTLLPSSPTSAP 2865 Query: 1549 LSS 1551 +++ Sbjct: 2866 ITT 2868 Score = 122 bits (307), Expect = 3e-27 Identities = 187/725 (25%), Positives = 271/725 (37%), Gaps = 80/725 (11%) Query: 405 TAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVL 464 TA+T ++ TP+ P A PPK +PA P + ++ +P T TT+ VL Sbjct: 4263 TASTGSTATPSSTPGT-APPPK----VLTSPATTP---TATSSKATSSSSPRTATTLPVL 4314 Query: 465 PTVPGSSISVPTAARTQGVPA-VLKVTG--PQATTGTPLVTMRPASQAGKAPVTVTSLPA 521 + S TA +P+ L TG P+ TT TP+ TM + T TS Sbjct: 4315 TSTATKS----TATSVTPIPSSTLGTTGTLPEQTT-TPVATMSTIHPSSTPETTHTSTVL 4369 Query: 522 GVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580 + ++ + S+P + + L AA T P++ P+ S P T I Sbjct: 4370 TTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPS--STPGTTWI---- 4423 Query: 581 AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGT 640 +T TTT T S+ S P T + T + T +T+T S T Sbjct: 4424 -LTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTAT-------ASST 4475 Query: 641 VTVAQQAQVVTTVVGGVTKTITLVK-SPISVPGGSALISNLGKVMSVVQTKPVQTS--AV 697 A V TT T T+T K +P S PG + + L T P TS A+ Sbjct: 4476 QATAGTPHVSTT---ATTPTVTSSKATPSSSPGTATALPALRS----TATTPTATSFTAI 4528 Query: 698 TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVS 757 + T++ QT P T + P T+ T+T + T G S + Sbjct: 4529 PSSSLGTTWTRLSQTTTP----TATMSTATPSSTPETVHTSTVLTATATTTGATG-SVAT 4583 Query: 758 PSTTKPGTTTIIK-----TIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSG-TGAP 811 PS+T PGT K T +A + + T +T I + T TT TSG T P Sbjct: 4584 PSST-PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTP 4642 Query: 812 AKI--ITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAV 869 + I T ++ T T V G+ P + +T T T++A Sbjct: 4643 SSIPGTTHTARVLT-----TTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTT 4697 Query: 870 TTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAI 929 GTT +T + T T T + + S+S AT + L + AT S + T I Sbjct: 4698 NPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTAT-KSTATSFTPI 4756 Query: 930 TVSAAQTTLTAAGGLTTPTITMQPV---SQP---------TQVTLITAPSGVEAQPVHDL 977 S TT T TTP TM + S P T +T + A P L Sbjct: 4757 PSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTL 4816 Query: 978 PVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANL 1037 + + + T T T + PGT ++ T T +TAT + + L Sbjct: 4817 GTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATAS--STL 4874 Query: 1038 GGHPQPTQVQFVCDRQEAAASLV--TSTVGQQNGSVVRVCSNPPCETHETGTTNTATTAT 1095 G P V + A AS V +STVG V S P T T +++ T Sbjct: 4875 GTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLP---TFSVSTVSSSVLTT 4931 Query: 1096 SNMAG 1100 G Sbjct: 4932 LRPTG 4936 Score = 122 bits (306), Expect = 4e-27 Identities = 333/1519 (21%), Positives = 508/1519 (33%), Gaps = 280/1519 (18%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 P+T AT+++ TP+ P K P A A T + L + AP P TT Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTK-PTTTATTTASTGSTATPTSTL-RTAPPPKVLTTTA 1946 Query: 463 VLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAG 522 PTV S + P+ T T L +R + A +VT +P+ Sbjct: 1947 TTPTVTSS----------KATPS------SSPGTATALPALRSTATTPTA-TSVTPIPS- 1988 Query: 523 VRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT----IVK 578 S+ GT Q + A + A + + TVL+ A TT V Sbjct: 1989 --------SSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVA 2040 Query: 579 TMAVTPG---TTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635 T + TPG TT +P T + S+P T + T + T+ + T S TV Sbjct: 2041 TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL--TPPVWISTTTTPTTRGS-----TV 2093 Query: 636 HKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTS 695 S A V+TT T T+ ++ P S S T P T+ Sbjct: 2094 TPSSIPGTTHTATVLTTT------TTTVATGSMATPSSSTQTSG---------TPPSLTT 2138 Query: 696 AVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISS 755 T +TG T T G P + L T+A T T T +S GT T Sbjct: 2139 TATTITATGSTTNPSSTPGTTPIPPV--LTTTATTPAATSNTVTPSSALGTTHT------ 2190 Query: 756 VSPSTTKPGTTTIIKTIPMSAIIT-----QAGATGVTSSPGIKSPITIITTKVMTSGTGA 810 P TT +++P S+ T + +G+ + I P T +T+ + + TG Sbjct: 2191 --PPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST-VTSHTLAATTGT 2247 Query: 811 PAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVT 870 + P +++ H T+ +P PGT T P G + T +A Sbjct: 2248 TQH---STPALSSPHPSSRTTE-----SPPSPGT---TTP-GHTTATSRTTATATPSKTR 2295 Query: 871 TLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAIT 930 T + ++ + T T+ A S P + G T S+ A+ Sbjct: 2296 TSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAV- 2354 Query: 931 VSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPV------HDLPVSILAS 984 Q P + ++ + Q + +L + V + + + Sbjct: 2355 --CEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCC 2412 Query: 985 PTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPT 1044 P+ T + + PGT ++ T T TATTT P T Sbjct: 2413 NYGHCPSTPAT-SSTAMPSSTPGTTWIL----------TELTTTATTTESTGSTATPSST 2461 Query: 1045 Q-VQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHG 1103 ++ A++ T S + + P T TT T T++ + G Sbjct: 2462 PGTTWILTEPSTTATVTVPTGSTATASSTQATAGTP-HVSTTATTPTVTSSKATPFSSPG 2520 Query: 1104 CSNPPCETHETGTTNTATT----AMSSVGANHQRDAR---------RACAAGTPAVIRIS 1150 + T TT TAT+ SS+G R ++ A + TP + S Sbjct: 2521 TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTS 2580 Query: 1151 ---VATGALEAAQGS-KSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSP 1206 T A GS + T T+ T+ +T TG +A P P AR P Sbjct: 2581 TVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTG--FTATPSSSPGTAR----TLP 2634 Query: 1207 AFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQ--GG 1264 ++ + R S+ + +P H+ V T T + G+ MA S Q G Sbjct: 2635 VWIS-TTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGS----MATPSSSTQTSGT 2689 Query: 1265 SPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCET 1324 PS T T T + A + + T S P T TATT A S+ S+ Sbjct: 2690 PPSLTTTATTITA----TGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS----- 2740 Query: 1325 HETGTTHTA----TTATSNGGTGQPEGGQQPPAGRPCETHQTTST-GTTMSVSVGALLPD 1379 GTTHT TTAT++G + P P R T T+ T GTT P Sbjct: 2741 -ALGTTHTPPVPNTTATTHGRSLSP---SSPHTVRTAWTSATSGTLGTTHITE-----PS 2791 Query: 1380 ATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPP-----CETHETGTTHTAT 1434 +SH AA T + AL +P P+ R +PP H T+ T Sbjct: 2792 TGTSHTP-------AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTA 2844 Query: 1435 TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT---TVTQST 1491 T T + + P++ +S+ ITT V+ + S Sbjct: 2845 TATPSKTRTSTLLPSS----------------PTSAPITTVVTMGCEPQCAWSEWLDYSY 2888 Query: 1492 PVPGPS-----------------VPPPEELQVSPGPRQQLPPRQLLQSASTAL------- 1527 P+PGPS P L+ + +P R+L Q +L Sbjct: 2889 PMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCR 2948 Query: 1528 ----MGE--------------------SAEVLSASQTP------------ELPAAVDLSS 1551 +G+ S S++ TP + AA ++ Sbjct: 2949 NREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTAT 3008 Query: 1552 TGE---PSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE------LMAEAQAGTT-- 1600 TG PSS +A V T P T S+ S P+ L + A T Sbjct: 3009 TGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATS 3068 Query: 1601 -------TLMVTGLTPEELAVTAAAEAAAQAAATEE----AQALAIQAVLQAAQQAVMGT 1649 TL TG PE+ A + ++T E + L +A A ++ Sbjct: 3069 FTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTP 3128 Query: 1650 GEPMDTSEAAATVTQAELGHLSAEGQEGQATTIP---IVLTQQELAALVQQQQLQEAQAQ 1706 T+ +T A +A G ++ P +LT+ A V A A Sbjct: 3129 SSTPGTTWILTELTTAAT-TTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS 3187 Query: 1707 QQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQP 1766 T + + + I S + P T LP+ + + P+ T V P Sbjct: 3188 STRATAGTLKVLTSTATTPTVISSRA---TPSSSPGTATALPALRSTATTPTATSVTAIP 3244 Query: 1767 VVVASPAKLQAAATLTEVA 1785 A + + T T A Sbjct: 3245 SSSLGTAWTRLSQTTTPTA 3263 Score = 115 bits (289), Expect = 3e-25 Identities = 177/695 (25%), Positives = 262/695 (37%), Gaps = 72/695 (10%) Query: 366 PPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPAN-- 423 PP +V A T + S +++ L AT +TATS TP P ++ Sbjct: 4280 PPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4339 Query: 424 -PPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQG 482 P ++ P A + P + P TT T VL T ++ + + + Sbjct: 4340 LPEQTTTPVATMSTIHP------------SSTPETTHTSTVLTTKATTTRATSSTSTPSS 4387 Query: 483 VPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQ 542 P + T T P + P T L T S T SS Sbjct: 4388 TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTP 4447 Query: 543 MSGMAALAAAAAATQKIPPSSAPTVLS--VPAGTTIVKTMAVTPGTTTLPATVKVASSP- 599 + + AT +P S T S AGT V T A TP T+ AT +SSP Sbjct: 4448 GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT--PSSSPG 4505 Query: 600 VMVSNPATRMLKTAAAQVGTSV-----SSATNTSTRPIITVHKSGTVTVAQQAQ----VV 650 + PA R TA TS SS T TR T + T++ A + V Sbjct: 4506 TATALPALR--STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVH 4563 Query: 651 TTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQT-SAVTGQASTGPV--- 706 T+ V T T T ++ P + ++ KV + T T S+ G A T PV Sbjct: 4564 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS 4623 Query: 707 -TQIIQTKGPLPAGTILKLV----TSADGKPTTIITTTQASGAGTKPTILGISSVSPSTT 761 T T P +G+ + T+ + T TTT A+G+ P+ SS S T Sbjct: 4624 TTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPS----SSTQTSGT 4679 Query: 762 KPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKI 821 P TT TI ATG T++P +P T T V+TS PA K Sbjct: 4680 PPSLTTTATTIT---------ATGSTTNPS-STPGTTPITPVLTSTATTPA---ATSSKA 4726 Query: 822 ATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVT 881 + + T + + + T P+ L T TV PA TT + + + Sbjct: 4727 TSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTV----PAQTTTPMSTMSTIH 4782 Query: 882 TLGTVTGTVSTSLAGAGGHSTSA--SLATPITTLGTIATLSSQVINPTAITVSAAQTTLT 939 T T T ++++ T A S ATP +TLGT L+ + TA T +A +T T Sbjct: 4783 TSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTE--LTTTATTTAATGSTAT 4840 Query: 940 AAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTT---EQPTATVTI 996 + +TP T +++P+ + + P+G A L + T PTAT + Sbjct: 4841 LS---STPGTTW-ILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATAST 4896 Query: 997 ADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S T ++ S+ P + T +++ TT Sbjct: 4897 VPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTT 4931 Score = 82.0 bits (201), Expect = 5e-15 Identities = 101/399 (25%), Positives = 164/399 (41%), Gaps = 41/399 (10%) Query: 365 PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANP 424 P V T + + G+VAT S +P T T + TP+ P P Sbjct: 4559 PETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP 4618 Query: 425 PKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT-----VPGSSISVPTAAR 479 P + P T G T+ P + P TT T +VL T GS + ++ + Sbjct: 4619 PVWISTTTTPTTTTPTTS-GSTVTPSSIPG--TTHTARVLTTTTTTVATGSMATPSSSTQ 4675 Query: 480 TQGVPAVLKVTGPQAT-TGTPLVTMRPASQAGKAPVT-----VTSLPAGVRMVVPTQSAQ 533 T G P L T T TG+ T P+S G P+T + PA + S+ Sbjct: 4676 TSGTPPSLTTTATTITATGS---TTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSP 4732 Query: 534 GTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATV 593 T + P ++ A + A + T IP S+ T +VPA TT + T T++ P T Sbjct: 4733 RTAT-TLPVLTSTATKSTATSFT-PIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETT 4790 Query: 594 KVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV 653 ++ +++ AT T + T+ S+T +TR + + + T T A + + Sbjct: 4791 HTST---VLTTTATMTRATNS----TATPSSTLGTTRILTELTTTATTTAATGSTATLSS 4843 Query: 654 VGGVTKTIT--LVKSPISVPGGSALI--SNLG-----KVMSVVQTKPVQTSAVTGQASTG 704 G T +T + + VP GS S LG KV++ + T P T++ +ST Sbjct: 4844 TPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTV 4903 Query: 705 PVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASG 743 T +T LP+ V++ ++++TT + +G Sbjct: 4904 GTT---RTPAVLPSSLPTFSVSTVS---SSVLTTLRPTG 4936 Score = 81.3 bits (199), Expect = 9e-15 Identities = 125/543 (23%), Positives = 197/543 (36%), Gaps = 115/543 (21%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 + T ++ V G+ ATA S P + TAT+PT V S A P SP A A Sbjct: 4457 STTATVTVPTGSTATASSTQATA---GTPHVSTTATTPT---VTSSKATPSSSPGTATAL 4510 Query: 435 PAVQ--------------PLTQVGITLLPQAAPAPPTTTTIQVLP--------------- 465 PA++ P + +G T + PT T P Sbjct: 4511 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTA 4570 Query: 466 --TVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKA----------- 512 T G++ SV T + T G KV TT T T P+S G A Sbjct: 4571 TATTTGATGSVATPSSTPGTAHTTKVP----TTTTTGFTATPSSSPGTALTPPVWISTTT 4626 Query: 513 -PVTVTSLPAGVRMV---VP--TQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566 P T T +G + +P T +A+ ++ +G A +++ T PPS T Sbjct: 4627 TPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTT 4686 Query: 567 VLSVPAGTTIVKTMAVTPGTTTL-PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 ++ A T + TPGTT + P A++P S+ AT A ++S Sbjct: 4687 ATTITA-TGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTA 4745 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 ST T S T+ TT TI +P + ++ V++ Sbjct: 4746 TKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPET--------THTSTVLT 4797 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAG 745 T T++ +ST T+I+ + TT TTT A+G Sbjct: 4798 TTATMTRATNSTATPSSTLGTTRILT-------------------ELTTTATTTAATG-- 4836 Query: 746 TKPTILGISSVSPSTTKPGTTTII-KTIPMSAIITQAGATGVTSSPGIKSPITIITTKVM 804 S + ++ PGTT I+ + ++ ++ G+T SS + T T KV+ Sbjct: 4837 ---------STATLSSTPGTTWILTEPSTIATVMVPTGSTATASS----TLGTAHTPKVV 4883 Query: 805 TSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSA 864 T+ P + VP +T G P + ++P V V+ ++ Sbjct: 4884 TTMATMPTATASTVPSSST------------VGTTRTPAVLPSSLPTFSVSTVSSSVLTT 4931 Query: 865 VKP 867 ++P Sbjct: 4932 LRP 4934 >gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 161 bits (408), Expect = 5e-39 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620 GS T T S + E + AG TTT +G T + + Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 +A +E A I + A A + EP TS + T ++A G +T Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278 Query: 1681 TI 1682 T+ Sbjct: 1279 TV 1280 Score = 154 bits (389), Expect = 8e-37 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 + T +S+ GA D+ AA T +V+T E S + +T S T Sbjct: 560 GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 + T +T SS + G + Sbjct: 620 GSETTTAST------------------------------------TSSETTTASTEGSET 643 Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293 VST + V G R E GS +TTV+ T E + + T S Sbjct: 644 TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699 Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351 ET + TT T TTS GS S ET T + TT S G+ E Sbjct: 700 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756 Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384 G T TTS+ TTM+ +G+ + T + Sbjct: 757 TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 T V+ A S T A T A T S ET T + TT S SS Sbjct: 817 TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + ST+G TS+ TT +ST +TTV+ + + E Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564 + +L S + + E +E + + T S+ G ++ +AGS Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623 + T S S E + GT TT+ T + TA +E A Sbjct: 992 ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046 Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679 E + + + V TG T+ A TV+ + G +A + Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732 TT+ I T+ A V + A + T +++ I S Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 + AG+ +T + S T T S A S T A + A + T T G E+ Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223 Score = 146 bits (369), Expect = 2e-34 Identities = 260/1174 (22%), Positives = 425/1174 (36%), Gaps = 149/1174 (12%) Query: 451 AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 A+ P TT + + TV + A+ + TG + TT + + + Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566 + T S T+ ++ T + ++ + ++ + T S Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 567 VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619 V + TT T + + TT +T ++ V + T+ T ++ T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483 Query: 620 SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679 + +S T T + T+ T + ++ TT V +T V + S + +S Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538 Query: 680 LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727 G + V T ++T S +T ++TG T T+G AG+ V++ Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 728 ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780 AD + TT T TT AS G++ T +S + ST TTT+ T + +++ Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658 Query: 781 AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834 G+ +TS+ G ++ T T V T G+G IT K++T + T Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717 Query: 835 LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892 G+ + T + G T T + TT +G TT +T G+ T T ST Sbjct: 718 -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767 Query: 893 SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940 + + S S T +T+G+ ++T SS++ A T ++ TT++ Sbjct: 768 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827 Query: 941 AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 AG T P T ++ T T+ G E + T T T T Sbjct: 828 AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879 Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060 G+ T S ET T T + TTT A+ G T + A+ Sbjct: 880 ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931 Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109 +T GS + S ET ET T T + T T++ AG S Sbjct: 932 ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160 ET + TT +SS G+ + GT I ++ A A Sbjct: 992 ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047 Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217 + S+ T T + TT TV TG+ S L +++ G + A + ++ Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106 Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277 S + G + VST + ++ M V ++ + +T+ A + Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166 Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337 S T T T + T T S AGS S ET+ TT + T+ Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226 Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392 S+ G+ ET+ G+ T S +L P AT S TV Sbjct: 1227 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440 A A S T + T +L Q + + P T TGT TA++ T++ Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 +S+ P + G ST G S + TS+ + TT ST +T ++ GP Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534 + +S P + P LQ + L+ +A V Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420 Score = 140 bits (353), Expect = 1e-32 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + TT T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 124 bits (312), Expect = 7e-28 Identities = 214/959 (22%), Positives = 336/959 (35%), Gaps = 105/959 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779 +A K TT+ T TT AS ++ T + G ++ ST TTT T Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856 Query: 780 QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836 + T++ S T TT + T+ T T+ T +++ Sbjct: 857 STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 837 GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890 G T T T TVS T+ +G TT VTT+G+ T T Sbjct: 917 STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976 Query: 891 STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945 ST AG +T+ S A TT +I T+SS T ++ + +TT+T+ G Sbjct: 977 ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032 Query: 946 TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002 T T+T T + + + VS S TT TA T T++ SG G Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 G+ T S E TT++ TTT A+ G T V Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108 + + +T GS S ET T + TT S + S Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168 ET+ TT + T+ SS G+ + A G+ I +T +LE S + +T Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1263 Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215 S T S+T V+ S P+ M+ R G R A S Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1316 Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269 S V + +P + D A SH V +T+ + S++GA A + G + T Sbjct: 1317 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373 Score = 58.9 bits (141), Expect = 5e-08 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%) Query: 446 TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505 T + + A +TT T + + T T + G +ATT + + Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174 Query: 506 ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565 + + T S T ++ T +S + A + +T S Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T + + TTI T ++ P T+L + ++ V ++ T + ++ AT Sbjct: 1235 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1291 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684 + S +PI SGT T + ++V T + +VPG S LG M Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351 Query: 685 SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736 T T ++ P + Q GP+ GT S PT +I Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1400 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 161 bits (408), Expect = 5e-39 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620 GS T T S + E + AG TTT +G T + + Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 +A +E A I + A A + EP TS + T ++A G +T Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278 Query: 1681 TI 1682 T+ Sbjct: 1279 TV 1280 Score = 154 bits (389), Expect = 8e-37 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 + T +S+ GA D+ AA T +V+T E S + +T S T Sbjct: 560 GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 + T +T SS + G + Sbjct: 620 GSETTTAST------------------------------------TSSETTTASTEGSET 643 Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293 VST + V G R E GS +TTV+ T E + + T S Sbjct: 644 TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699 Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351 ET + TT T TTS GS S ET T + TT S G+ E Sbjct: 700 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756 Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384 G T TTS+ TTM+ +G+ + T + Sbjct: 757 TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 T V+ A S T A T A T S ET T + TT S SS Sbjct: 817 TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + ST+G TS+ TT +ST +TTV+ + + E Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564 + +L S + + E +E + + T S+ G ++ +AGS Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623 + T S S E + GT TT+ T + TA +E A Sbjct: 992 ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046 Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679 E + + + V TG T+ A TV+ + G +A + Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732 TT+ I T+ A V + A + T +++ I S Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 + AG+ +T + S T T S A S T A + A + T T G E+ Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223 Score = 147 bits (370), Expect = 1e-34 Identities = 260/1174 (22%), Positives = 425/1174 (36%), Gaps = 149/1174 (12%) Query: 451 AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 A+ P TT + + TV + A+ + TG + TT + + + Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566 + T S T+ ++ T + ++ + ++ + T S Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 567 VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619 V + TT T + + TT +T ++ V + T+ T ++ T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483 Query: 620 SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679 + +S T T + T+ T + ++ TT V +T V + S + +S Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538 Query: 680 LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727 G + V T ++T S +T ++TG T T+G AG+ V++ Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 728 ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780 AD + TT T TT AS G++ T +S + ST TTT+ T + +++ Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658 Query: 781 AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834 G+ +TS+ G ++ T T V T G+G IT K++T + T Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717 Query: 835 LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892 G+ + T + G T T + TT +G TT +T G+ T T ST Sbjct: 718 -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767 Query: 893 SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940 + + S S T +T+G+ ++T SS++ A T ++ TT++ Sbjct: 768 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827 Query: 941 AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 AG T P T ++ T T+ G E + T T T T Sbjct: 828 AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879 Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060 G+ T S ET T T + TTT A+ G T + A+ Sbjct: 880 ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931 Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109 +T GS + S ET ET T T + T T++ AG S Sbjct: 932 ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160 ET + TT +SS G+ + GT I ++ A A Sbjct: 992 ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047 Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217 + S+ T T + TT TV TG+ S L +++ G + A + ++ Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106 Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277 S + G + VST + ++ M V ++ + +T+ A + Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166 Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337 S T T T + T T S AGS S ET+ TT + T+ Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226 Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392 S+ G+ ET+ G+ T S +L P AT S TV Sbjct: 1227 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440 A A S T + T +L Q + + P T TGT TA++ T++ Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASA 1331 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 +S+ P + G ST G S + TS+ + TT ST +T ++ GP Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534 + +S P + P LQ + L+ +A V Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420 Score = 140 bits (353), Expect = 1e-32 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + TT T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 125 bits (313), Expect = 5e-28 Identities = 212/959 (22%), Positives = 334/959 (34%), Gaps = 105/959 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779 +A K TT+ T TT AS ++ T + G ++ ST TTT T Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856 Query: 780 QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836 + T++ S T TT + T+ T T+ T +++ Sbjct: 857 STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 837 GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890 G T T T TVS T+ +G TT VTT+G+ T T Sbjct: 917 STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976 Query: 891 STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945 ST AG +T+ S A TT +I T+SS T ++ + +TT+T+ G Sbjct: 977 ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032 Query: 946 TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002 T T+T T + + + VS S TT TA T T++ SG G Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 G+ T S E TT++ TTT A+ G T V Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108 + + +T GS S ET T + TT S + S Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168 ET+ TT + T+ SS G+ + A G+ I +T +LE S + +T Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1263 Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215 S T S+T V+ S P+ M+ R G R P + Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTR--------PTA 1315 Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269 S +P + D A SH V +T+ + S++GA A + G + T Sbjct: 1316 SSSVTMAPGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373 Score = 58.9 bits (141), Expect = 5e-08 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%) Query: 446 TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505 T + + A +TT T + + T T + G +ATT + + Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174 Query: 506 ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565 + + T S T ++ T +S + A + +T S Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T + + TTI T ++ P T+L + ++ V ++ T + ++ AT Sbjct: 1235 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1291 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684 + S +PI SGT T + ++V T + +VPG S LG M Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351 Query: 685 SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736 T T ++ P + Q GP+ GT S PT +I Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1400 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] Length = 1704 Score = 161 bits (408), Expect = 5e-39 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620 GS T T S + E + AG TTT +G T + + Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 +A +E A I + A A + EP TS + T ++A G +T Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278 Query: 1681 TI 1682 T+ Sbjct: 1279 TV 1280 Score = 154 bits (389), Expect = 8e-37 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 + T +S+ GA D+ AA T +V+T E S + +T S T Sbjct: 560 GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 + T +T SS + G + Sbjct: 620 GSETTTAST------------------------------------TSSETTTASTEGSET 643 Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293 VST + V G R E GS +TTV+ T E + + T S Sbjct: 644 TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699 Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351 ET + TT T TTS GS S ET T + TT S G+ E Sbjct: 700 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756 Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384 G T TTS+ TTM+ +G+ + T + Sbjct: 757 TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 T V+ A S T A T A T S ET T + TT S SS Sbjct: 817 TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + ST+G TS+ TT +ST +TTV+ + + E Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564 + +L S + + E +E + + T S+ G ++ +AGS Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623 + T S S E + GT TT+ T + TA +E A Sbjct: 992 ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046 Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679 E + + + V TG T+ A TV+ + G +A + Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732 TT+ I T+ A V + A + T +++ I S Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 + AG+ +T + S T T S A S T A + A + T T G E+ Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223 Score = 147 bits (370), Expect = 1e-34 Identities = 260/1174 (22%), Positives = 425/1174 (36%), Gaps = 149/1174 (12%) Query: 451 AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 A+ P TT + + TV + A+ + TG + TT + + + Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566 + T S T+ ++ T + ++ + ++ + T S Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 567 VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619 V + TT T + + TT +T ++ V + T+ T ++ T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483 Query: 620 SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679 + +S T T + T+ T + ++ TT V +T V + S + +S Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538 Query: 680 LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727 G + V T ++T S +T ++TG T T+G AG+ V++ Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 728 ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780 AD + TT T TT AS G++ T +S + ST TTT+ T + +++ Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658 Query: 781 AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834 G+ +TS+ G ++ T T V T G+G IT K++T + T Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717 Query: 835 LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892 G+ + T + G T T + TT +G TT +T G+ T T ST Sbjct: 718 -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767 Query: 893 SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940 + + S S T +T+G+ ++T SS++ A T ++ TT++ Sbjct: 768 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827 Query: 941 AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 AG T P T ++ T T+ G E + T T T T Sbjct: 828 AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879 Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060 G+ T S ET T T + TTT A+ G T + A+ Sbjct: 880 ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931 Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109 +T GS + S ET ET T T + T T++ AG S Sbjct: 932 ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160 ET + TT +SS G+ + GT I ++ A A Sbjct: 992 ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047 Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217 + S+ T T + TT TV TG+ S L +++ G + A + ++ Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106 Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277 S + G + VST + ++ M V ++ + +T+ A + Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166 Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337 S T T T + T T S AGS S ET+ TT + T+ Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226 Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392 S+ G+ ET+ G+ T S +L P AT S TV Sbjct: 1227 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440 A A S T + T +L Q + + P T TGT TA++ T++ Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASA 1331 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 +S+ P + G ST G S + TS+ + TT ST +T ++ GP Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534 + +S P + P LQ + L+ +A V Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420 Score = 140 bits (353), Expect = 1e-32 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + TT T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 125 bits (313), Expect = 5e-28 Identities = 212/959 (22%), Positives = 334/959 (34%), Gaps = 105/959 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779 +A K TT+ T TT AS ++ T + G ++ ST TTT T Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856 Query: 780 QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836 + T++ S T TT + T+ T T+ T +++ Sbjct: 857 STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 837 GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890 G T T T TVS T+ +G TT VTT+G+ T T Sbjct: 917 STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976 Query: 891 STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945 ST AG +T+ S A TT +I T+SS T ++ + +TT+T+ G Sbjct: 977 ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032 Query: 946 TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002 T T+T T + + + VS S TT TA T T++ SG G Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 G+ T S E TT++ TTT A+ G T V Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108 + + +T GS S ET T + TT S + S Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168 ET+ TT + T+ SS G+ + A G+ I +T +LE S + +T Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1263 Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215 S T S+T V+ S P+ M+ R G R P + Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTR--------PTA 1315 Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269 S +P + D A SH V +T+ + S++GA A + G + T Sbjct: 1316 SSSVTMAPGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373 Score = 58.9 bits (141), Expect = 5e-08 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%) Query: 446 TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505 T + + A +TT T + + T T + G +ATT + + Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174 Query: 506 ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565 + + T S T ++ T +S + A + +T S Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T + + TTI T ++ P T+L + ++ V ++ T + ++ AT Sbjct: 1235 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1291 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684 + S +PI SGT T + ++V T + +VPG S LG M Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351 Query: 685 SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736 T T ++ P + Q GP+ GT S PT +I Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1400 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] Length = 1612 Score = 161 bits (407), Expect = 7e-39 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620 GS T T S + E + AG TTT +G T + + Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 +A +E A I + A A + EP TS + T ++A G +T Sbjct: 1225 TPSSAGSETNTAFIIGSESTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278 Query: 1681 TI 1682 T+ Sbjct: 1279 TV 1280 Score = 154 bits (389), Expect = 8e-37 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 + T +S+ GA D+ AA T +V+T E S + +T S T Sbjct: 560 GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 + T +T SS + G + Sbjct: 620 GSETTTAST------------------------------------TSSETTTASTEGSET 643 Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293 VST + V G R E GS +TTV+ T E + + T S Sbjct: 644 TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699 Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351 ET + TT T TTS GS S ET T + TT S G+ E Sbjct: 700 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756 Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384 G T TTS+ TTM+ +G+ + T + Sbjct: 757 TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 T V+ A S T A T A T S ET T + TT S SS Sbjct: 817 TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + ST+G TS+ TT +ST +TTV+ + + E Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564 + +L S + + E +E + + T S+ G ++ +AGS Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623 + T S S E + GT TT+ T + TA +E A Sbjct: 992 ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046 Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679 E + + + V TG T+ A TV+ + G +A + Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732 TT+ I T+ A V + A + T +++ I S Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 + AG+ +T + S T T S A S T A + A + T T G E+ Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223 Score = 146 bits (369), Expect = 2e-34 Identities = 259/1174 (22%), Positives = 426/1174 (36%), Gaps = 149/1174 (12%) Query: 451 AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 A+ P TT + + TV + A+ + TG + TT + + + Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566 + T S T+ ++ T + ++ + ++ + T S Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 567 VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619 V + TT T + + TT +T ++ V + T+ T ++ T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483 Query: 620 SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679 + +S T T + T+ T + ++ TT V +T V + S + +S Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538 Query: 680 LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727 G + V T ++T S +T ++TG T T+G AG+ V++ Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 728 ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780 AD + TT T TT AS G++ T +S + ST TTT+ T + +++ Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658 Query: 781 AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834 G+ +TS+ G ++ T T V T G+G IT K++T + T Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717 Query: 835 LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892 G+ + T + G T T + TT +G TT +T G+ T T ST Sbjct: 718 -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767 Query: 893 SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940 + + S S T +T+G+ ++T SS++ A T ++ TT++ Sbjct: 768 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827 Query: 941 AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 AG T P T ++ T T+ G E + T T T T Sbjct: 828 AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879 Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060 G+ T S ET T T + TTT A+ G T + A+ Sbjct: 880 ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931 Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109 +T GS + S ET ET T T + T T++ AG S Sbjct: 932 ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160 ET + TT +SS G+ + GT I ++ A A Sbjct: 992 ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047 Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217 + S+ T T + TT TV TG+ S L +++ G + A + ++ Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106 Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277 S + G + VST + ++ M V ++ + +T+ A + Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166 Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337 S T T T + T T S AGS S ET+ TT + T+ Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226 Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSV-SVGALLPDAT----SSHRTVESGLE 1392 S+ G+ ET+ G+ ++ S +L P AT S TV Sbjct: 1227 SSAGS---------------ETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440 A A S T + T +L Q + + P T TGT TA++ T++ Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 +S+ P + G ST G S + TS+ + TT ST +T ++ GP Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534 + +S P + P LQ + L+ +A V Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420 Score = 140 bits (353), Expect = 1e-32 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + TT T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 125 bits (313), Expect = 5e-28 Identities = 214/959 (22%), Positives = 337/959 (35%), Gaps = 105/959 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779 +A K TT+ T TT AS ++ T + G ++ ST TTT T Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856 Query: 780 QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836 + T++ S T TT + T+ T T+ T +++ Sbjct: 857 STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 837 GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890 G T T T TVS T+ +G TT VTT+G+ T T Sbjct: 917 STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976 Query: 891 STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945 ST AG +T+ S A TT +I T+SS T ++ + +TT+T+ G Sbjct: 977 ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032 Query: 946 TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002 T T+T T + + + VS S TT TA T T++ SG G Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 G+ T S E TT++ TTT A+ G T V Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108 + + +T GS S ET T + TT S + S Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168 ET+ TT + T+ SS G+ + A G+ + I +T +LE S + +T Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSESTI---ASTASLEPTATSLTGSET 1263 Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215 S T S+T V+ S P+ M+ R G R A S Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1316 Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269 S V + +P + D A SH V +T+ + S++GA A + G + T Sbjct: 1317 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] Length = 1542 Score = 161 bits (407), Expect = 7e-39 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 60 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTIS 119 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 120 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 179 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 180 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 236 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 237 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 294 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 295 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 347 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 348 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 397 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 398 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 457 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 458 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 512 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 513 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 572 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 573 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 627 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 628 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 680 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 681 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 735 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 736 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 785 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 786 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 839 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 840 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 893 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 894 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 953 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 954 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 1013 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 1014 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1072 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1073 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1132 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1133 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1190 Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620 GS T T S + E + AG TTT +G T + + Sbjct: 1191 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1245 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 +A +E A I + A A + EP TS + T ++A G +T Sbjct: 1246 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1299 Query: 1681 TI 1682 T+ Sbjct: 1300 TV 1301 Score = 157 bits (398), Expect = 8e-38 Identities = 294/1334 (22%), Positives = 451/1334 (33%), Gaps = 170/1334 (12%) Query: 529 TQSAQGTVIGSSPQMSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AV 582 T +A VI +S MS +A AA + T S T+L + TT T Sbjct: 9 TSTADSKVITAS-SMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT 67 Query: 583 TPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVT 642 TP T T+ S + + T + G+ ++A+ + I+ S T T Sbjct: 68 TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTT 127 Query: 643 VAQQAQVVTTV--VGGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA 696 V+ T V +G T T + S +V + +S +G + T +T+A Sbjct: 128 VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 187 Query: 697 --VTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGIS 754 TG T T +T P AG+ V++A + TT+ TT G+ T S Sbjct: 188 ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHS 243 Query: 755 SVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKI 814 + ++T TT + T ++ AG+ +S T T T+ Sbjct: 244 ETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE 303 Query: 815 ITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVV 874 TA TG ++ + G T+ T+ + VS VTT+ Sbjct: 304 TTAAS--TTG------SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFA 349 Query: 875 KG--TTGVTTLGTVTGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPT 927 G T +T+G+ T TVST+ G +T+AS+ +T TT T S++ T Sbjct: 350 AGSETIRASTVGSETTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETT 405 Query: 928 AITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTT 987 + ++ T + G T T+++ T T E + + ++ + T Sbjct: 406 TASTEGSEATTVSTTGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTA 457 Query: 988 EQPTATVTIADSGQGDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQP 1043 + +TIA + + G+ T + ET TT + TTT A+ G Sbjct: 458 STEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETT 515 Query: 1044 TQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHG 1103 T D A+ +T GS + S E TT + TT S Sbjct: 516 TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---- 571 Query: 1104 CSNPPCETHETGTTNTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQ 1160 ET T T + T +S+ GA D+ AA T +V+T E Sbjct: 572 -----LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 626 Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRL 1220 S + +T S T + T +T Sbjct: 627 ASTADSETTSASTTGSETTTAST------------------------------------T 650 Query: 1221 SSPSIKDLPAGRHSHAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALL 1279 SS + G + VST + V G R E GS +TTV+ T E + Sbjct: 651 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTV 706 Query: 1280 CPSATVTQVCSNPPCETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337 + T S ET + TT T TTS GS S ET T + TT Sbjct: 707 STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 766 Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALL-------------------- 1377 S G+ E G T TTS+ TTM+ +G+ Sbjct: 767 STEGS---ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 823 Query: 1378 -------PDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430 + T + T V+ A S T A T A T S ET T Sbjct: 824 TTVFTENSETTIASTTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTE 880 Query: 1431 HTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQS 1490 + TT S SS + ST+G TS+ TT +ST +TTV+ + Sbjct: 881 GSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 940 Query: 1491 TPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLS 1550 + E + +L S + + E +E + + T S Sbjct: 941 GSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTAS 998 Query: 1551 STGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTP 1609 + G ++ +AGS + T S S E + GT TT+ T + Sbjct: 999 TAGSETTTVSTAGSETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSE 1053 Query: 1610 EELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQA 1665 TA +E A E + + + V TG T+ A TV+ + Sbjct: 1054 TTTVTTAGSETTAVYTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTS 1110 Query: 1666 ELGHLSAEGQEGQATTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALA 1718 G +A + TT+ I T+ A V + A + T Sbjct: 1111 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1170 Query: 1719 PADSLNDPAIESNC-LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQ 1776 +++ I S + AG+ +T + S T T S A S T A + A Sbjct: 1171 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1230 Query: 1777 AAATLTEVANGIES 1790 + T T G E+ Sbjct: 1231 GSETNTACTTGSET 1244 Score = 146 bits (369), Expect = 2e-34 Identities = 260/1174 (22%), Positives = 425/1174 (36%), Gaps = 149/1174 (12%) Query: 451 AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 A+ P TT + + TV + A+ + TG + TT + + + Sbjct: 327 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 386 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566 + T S T+ ++ T + ++ + ++ + T S Sbjct: 387 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 446 Query: 567 VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619 V + TT T + + TT +T ++ V + T+ T ++ T Sbjct: 447 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 504 Query: 620 SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679 + +S T T + T+ T + ++ TT V +T V + S + +S Sbjct: 505 TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 559 Query: 680 LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727 G + V T ++T S +T ++TG T T+G AG+ V++ Sbjct: 560 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 619 Query: 728 ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780 AD + TT T TT AS G++ T +S + ST TTT+ T + +++ Sbjct: 620 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 679 Query: 781 AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834 G+ +TS+ G ++ T T V T G+G IT K++T + T Sbjct: 680 TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 738 Query: 835 LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892 G+ + T + G T T + TT +G TT +T G+ T T ST Sbjct: 739 -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 788 Query: 893 SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940 + + S S T +T+G+ ++T SS++ A T ++ TT++ Sbjct: 789 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 848 Query: 941 AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 AG T P T ++ T T+ G E + T T T T Sbjct: 849 AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 900 Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060 G+ T S ET T T + TTT A+ G T + A+ Sbjct: 901 ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 952 Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109 +T GS + S ET ET T T + T T++ AG S Sbjct: 953 ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 1012 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160 ET + TT +SS G+ + GT I ++ A A Sbjct: 1013 ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1068 Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217 + S+ T T + TT TV TG+ S L +++ G + A + ++ Sbjct: 1069 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1127 Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277 S + G + VST + ++ M V ++ + +T+ A + Sbjct: 1128 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1187 Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337 S T T T + T T S AGS S ET+ TT + T+ Sbjct: 1188 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1247 Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392 S+ G+ ET+ G+ T S +L P AT S TV Sbjct: 1248 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1292 Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440 A A S T + T +L Q + + P T TGT TA++ T++ Sbjct: 1293 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1352 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 +S+ P + G ST G S + TS+ + TT ST +T ++ GP Sbjct: 1353 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1407 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534 + +S P + P LQ + L+ +A V Sbjct: 1408 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1441 Score = 140 bits (353), Expect = 1e-32 Identities = 243/1113 (21%), Positives = 404/1113 (36%), Gaps = 114/1113 (10%) Query: 718 AGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI 777 AG+ ++AD K +IT + S T G ++ + STT TTTI+ + Sbjct: 2 AGSEATTTSTADSK---VITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTT 58 Query: 778 ITQAGATGVTSSP-GIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836 + AG+ T SP G ++ I I+ +T+ + A ++ T + G G + + Sbjct: 59 ASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVS---SAGSGTTTASMAGSE 115 Query: 837 GAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAG 896 G+ TV + G T V+ + + TT +T G+ T TVST + Sbjct: 116 STISTAGSETTTVSITGTE-TTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE 174 Query: 897 AGGHSTSASLATPITTLG----TIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQ 952 T+ S T +T G T+ T S+ I P+ T + TT++ AG TT T++ Sbjct: 175 TTTAYTADSETTAASTTGSEMTTVFTAGSETITPS--TAGSETTTVSTAGSETT-TVSTT 231 Query: 953 PVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTV--- 1009 T T + + VS S TT + T A S + D + T Sbjct: 232 GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE-DSETNTAFTE 290 Query: 1010 ---TLVCSNPPCETHETGTTNT---------ATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 T S ET TT + + TT+ + +G P+ T+V + A Sbjct: 291 DSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIG--PETTKV--------STA 340 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 S +TV +R S ET TT + TT S M ET TT Sbjct: 341 SSEVTTVFAAGSETIRA-STVGSETTTVSTTGSETTTASIMGS---------ETSTDSTT 390 Query: 1118 NTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTT 1177 + TT S+ G+ + A T + T ++ ++ + + + + +A STT Sbjct: 391 GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 450 Query: 1178 MTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAV 1237 + T + + + + E + A + + ++ S + G + Sbjct: 451 VFETTTASTEGSEITIASTSDSET---TTASTEGSETTTVTTAGSETKTAYTTGSETTTA 507 Query: 1238 STAAMTRSSVGA-GEPRMAPVCESLQGGSPSTTVTVTALE-ALLCPSATVTQVCSNPPCE 1295 S + ++V G E GS +T V+ T E + + S E Sbjct: 508 SNTGLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 563 Query: 1296 THETGTTN--TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPA 1353 T TT T TTS GS S ET T + TTA S G+ Sbjct: 564 TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS----------- 612 Query: 1354 GRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPT 1413 +TT+ T S + A D+ ++ + +G E A + + + TA T Sbjct: 613 -------ETTTVSTADSENTTASTADSETTSAST-TGSETTTASTTSSETTTASTEGSET 664 Query: 1414 QRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAIT 1473 V S ET TT + T+TS S A + V + + ++ + + T Sbjct: 665 TTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSET 723 Query: 1474 TTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGPRQQLPPRQLLQSASTALMGESA 1532 T VS+T + TT T+ + + S+ E S G + ++ S + G Sbjct: 724 TKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSET 783 Query: 1533 EVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSAVVATVVVQP-----PPPTQSEV 1582 S + + A++ ++ST + + S S+ + TV + T SE Sbjct: 784 TTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET 843 Query: 1583 DQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQA 1641 +S E + + AG+ T T E + + A+TE ++ + Sbjct: 844 TTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 903 Query: 1642 AQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQ 1701 A E TS + T A S EG E I V T + + Sbjct: 904 TTTASTEGSETTTTSTEGSETTTA-----STEGSE-----ITTVSTTGSETTTASTEGSE 953 Query: 1702 EAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPS-TATESLAPSNT 1760 A + L T + ++++ A G+ +TV + S T T S A S T Sbjct: 954 TTTASTEGSELTTVSTTGSETITVSA---------EGSETTTVTTMGSETTTASTAGSET 1004 Query: 1761 FVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 + A ++ + T T + G E+ V Sbjct: 1005 TTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1037 Score = 124 bits (312), Expect = 7e-28 Identities = 214/959 (22%), Positives = 336/959 (35%), Gaps = 105/959 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 477 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 534 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 535 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 594 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 595 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 654 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 655 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 711 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 712 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 762 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 763 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 817 Query: 727 SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779 +A K TT+ T TT AS ++ T + G ++ ST TTT T Sbjct: 818 TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 877 Query: 780 QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836 + T++ S T TT + T+ T T+ T +++ Sbjct: 878 STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 937 Query: 837 GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890 G T T T TVS T+ +G TT VTT+G+ T T Sbjct: 938 STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 997 Query: 891 STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945 ST AG +T+ S A TT +I T+SS T ++ + +TT+T+ G Sbjct: 998 ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1053 Query: 946 TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002 T T+T T + + + VS S TT TA T T++ SG G Sbjct: 1054 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1113 Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 G+ T S E TT++ TTT A+ G T V Sbjct: 1114 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1171 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108 + + +T GS S ET T + TT S + S Sbjct: 1172 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1231 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168 ET+ TT + T+ SS G+ + A G+ I +T +LE S + +T Sbjct: 1232 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1284 Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215 S T S+T V+ S P+ M+ R G R A S Sbjct: 1285 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1337 Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269 S V + +P + D A SH V +T+ + S++GA A + G + T Sbjct: 1338 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1394 Score = 58.9 bits (141), Expect = 5e-08 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%) Query: 446 TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505 T + + A +TT T + + T T + G +ATT + + Sbjct: 1136 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1195 Query: 506 ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565 + + T S T ++ T +S + A + +T S Sbjct: 1196 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1255 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T + + TTI T ++ P T+L + ++ V ++ T + ++ AT Sbjct: 1256 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1312 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684 + S +PI SGT T + ++V T + +VPG S LG M Sbjct: 1313 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1372 Query: 685 SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736 T T ++ P + Q GP+ GT S PT +I Sbjct: 1373 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1421 >gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo sapiens] Length = 1521 Score = 161 bits (407), Expect = 7e-39 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTI 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620 GS T T S + E + AG TTT +G T + + Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 +A +E A I + A A + EP TS + T ++A G +T Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278 Query: 1681 TI 1682 T+ Sbjct: 1279 TV 1280 Score = 153 bits (387), Expect = 1e-36 Identities = 276/1294 (21%), Positives = 443/1294 (34%), Gaps = 117/1294 (9%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTT 1177 + T +S+ GA D+ +GT A T + A + T + TS + Sbjct: 560 GSEMTTVSTTGAETTTDSTE--GSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617 Query: 1178 MTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAV 1237 T T +A + G V + + ++ S + + + S Sbjct: 618 TTGSET---TTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674 Query: 1238 STAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL-LCPSATVTQVCSNPPCET 1296 + +A + + E GS +TTV++T E + + + T + S E Sbjct: 675 TVSATGSETTVSTE------------GSGTTTVSITGSETTKVSTTGSETTITSTEGSEI 722 Query: 1297 HETGTT--NTATTSNAGSAQRVCSNPPCETHETGT----THTATTATSNGGTGQPEGGQQ 1350 T T T S GS S ET T T TA+T +S G + Sbjct: 723 TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782 Query: 1351 PPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAP 1410 A ST ++ +V + T + T V+ A S T A T A Sbjct: 783 TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST---AG 839 Query: 1411 FPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSS 1470 T S ET T + TT S SS + ST+G TS+ Sbjct: 840 SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTE 899 Query: 1471 AITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGE 1530 TT +ST +TTV+ + + E + +L S + + E Sbjct: 900 GSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959 Query: 1531 SAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE 1590 +E + + T S+ G ++ +AGS + T S S E Sbjct: 960 GSE--TTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS-----STGSE 1012 Query: 1591 LMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGT 1649 + GT TT+ T + TA +E A E + + + V T Sbjct: 1013 TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETTTVSTT 1069 Query: 1650 GEPMDTSEAA----ATVTQAELGHLSAEGQEGQATTIPI-------VLTQQELAALVQQQ 1698 G T+ A TV+ + G +A + TT+ I T+ A V Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTT 1129 Query: 1699 QLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC-LNELAGTVPSTVALLPS-TATESLA 1756 + A + T +++ I S + AG+ +T + S T T S A Sbjct: 1130 SSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1189 Query: 1757 PSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 S T A + A + T T G E+ Sbjct: 1190 GSETTTASTAGSETTTASTSGSETNTACTTGSET 1223 Score = 147 bits (372), Expect = 8e-35 Identities = 260/1174 (22%), Positives = 426/1174 (36%), Gaps = 149/1174 (12%) Query: 451 AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 A+ P TT + + TV + A+ + TG + TT + + + Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566 + T S T+ ++ T + ++ + ++ + T S Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 567 VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619 V + TT T + + TT +T ++ V + T+ T ++ T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483 Query: 620 SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679 + +S T T + T+ T + ++ TT V +T V + S + +S Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538 Query: 680 LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727 G + V T ++T S +T ++TG T T+G AG+ V++ Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 728 ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780 AD + TT T TT AS G++ T +S + ST TTT+ T + +++ Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658 Query: 781 AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834 G+ +TS+ G ++ T T V T G+G IT K++T + +T Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITST- 717 Query: 835 LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892 G+ + T + G T T + TT +G TT +T G+ T T ST Sbjct: 718 -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767 Query: 893 SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940 + + S S T +T+G+ ++T SS++ A T ++ TT++ Sbjct: 768 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827 Query: 941 AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 AG T P T ++ T T+ G E + T T T T Sbjct: 828 AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879 Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060 G+ T S ET T T + TTT A+ G T + A+ Sbjct: 880 ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931 Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109 +T GS + S ET ET T T + T T++ AG S Sbjct: 932 ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160 ET + TT +SS G+ + GT I ++ A A Sbjct: 992 ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047 Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217 + S+ T T + TT TV TG+ S L +++ G + A + ++ Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106 Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277 S + G + VST + ++ M V ++ + +T+ A + Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166 Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337 S T T T + T T S AGS S ET+ TT + T+ Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226 Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392 S+ G+ ET+ G+ T S +L P AT S TV Sbjct: 1227 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440 A A S T + T +L Q + + P T TGT TA++ T++ Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 +S+ P + G ST G S + TS+ + TT ST +T ++ GP Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534 + +S P + P LQ + L+ +A V Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420 Score = 138 bits (347), Expect = 6e-32 Identities = 240/1135 (21%), Positives = 396/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + T T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 125 bits (315), Expect = 3e-28 Identities = 214/959 (22%), Positives = 337/959 (35%), Gaps = 105/959 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T+T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779 +A K TT+ T TT AS ++ T + G ++ ST TTT T Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856 Query: 780 QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836 + T++ S T TT + T+ T T+ T +++ Sbjct: 857 STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 837 GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890 G T T T TVS T+ +G TT VTT+G+ T T Sbjct: 917 STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976 Query: 891 STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945 ST AG +T+ S A TT +I T+SS T ++ + +TT+T+ G Sbjct: 977 ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032 Query: 946 TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002 T T+T T + + + VS S TT TA T T++ SG G Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 G+ T S E TT++ TTT A+ G T V Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108 + + +T GS S ET T + TT S + S Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168 ET+ TT + T+ SS G+ + A G+ I +T +LE S + +T Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1263 Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215 S T S+T V+ S P+ M+ R G R A S Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1316 Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269 S V + +P + D A SH V +T+ + S++GA A + G + T Sbjct: 1317 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373 Score = 58.9 bits (141), Expect = 5e-08 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%) Query: 446 TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505 T + + A +TT T + + T T + G +ATT + + Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174 Query: 506 ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565 + + T S T ++ T +S + A + +T S Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 T + + TTI T ++ P T+L + ++ V ++ T + ++ AT Sbjct: 1235 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1291 Query: 626 NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684 + S +PI SGT T + ++V T + +VPG S LG M Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351 Query: 685 SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736 T T ++ P + Q GP+ GT S PT +I Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1400 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] Length = 1521 Score = 161 bits (407), Expect = 7e-39 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620 GS T T S + E + AG TTT +G T + + Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224 Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680 +A +E A I + A A + EP TS + T ++A G +T Sbjct: 1225 TPSSAGSETNTAFIIGSESTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278 Query: 1681 TI 1682 T+ Sbjct: 1279 TV 1280 Score = 154 bits (389), Expect = 8e-37 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 + T +S+ GA D+ AA T +V+T E S + +T S T Sbjct: 560 GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 + T +T SS + G + Sbjct: 620 GSETTTAST------------------------------------TSSETTTASTEGSET 643 Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293 VST + V G R E GS +TTV+ T E + + T S Sbjct: 644 TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699 Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351 ET + TT T TTS GS S ET T + TT S G+ E Sbjct: 700 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756 Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384 G T TTS+ TTM+ +G+ + T + Sbjct: 757 TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 T V+ A S T A T A T S ET T + TT S SS Sbjct: 817 TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + ST+G TS+ TT +ST +TTV+ + + E Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564 + +L S + + E +E + + T S+ G ++ +AGS Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623 + T S S E + GT TT+ T + TA +E A Sbjct: 992 ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046 Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679 E + + + V TG T+ A TV+ + G +A + Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732 TT+ I T+ A V + A + T +++ I S Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 + AG+ +T + S T T S A S T A + A + T T G E+ Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223 Score = 146 bits (369), Expect = 2e-34 Identities = 259/1174 (22%), Positives = 426/1174 (36%), Gaps = 149/1174 (12%) Query: 451 AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506 A+ P TT + + TV + A+ + TG + TT + + + Sbjct: 306 ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365 Query: 507 SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566 + T S T+ ++ T + ++ + ++ + T S Sbjct: 366 DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425 Query: 567 VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619 V + TT T + + TT +T ++ V + T+ T ++ T Sbjct: 426 VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483 Query: 620 SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679 + +S T T + T+ T + ++ TT V +T V + S + +S Sbjct: 484 TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538 Query: 680 LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727 G + V T ++T S +T ++TG T T+G AG+ V++ Sbjct: 539 TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598 Query: 728 ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780 AD + TT T TT AS G++ T +S + ST TTT+ T + +++ Sbjct: 599 ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658 Query: 781 AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834 G+ +TS+ G ++ T T V T G+G IT K++T + T Sbjct: 659 TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717 Query: 835 LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892 G+ + T + G T T + TT +G TT +T G+ T T ST Sbjct: 718 -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767 Query: 893 SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940 + + S S T +T+G+ ++T SS++ A T ++ TT++ Sbjct: 768 TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827 Query: 941 AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 AG T P T ++ T T+ G E + T T T T Sbjct: 828 AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879 Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060 G+ T S ET T T + TTT A+ G T + A+ Sbjct: 880 ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931 Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109 +T GS + S ET ET T T + T T++ AG S Sbjct: 932 ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160 ET + TT +SS G+ + GT I ++ A A Sbjct: 992 ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047 Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217 + S+ T T + TT TV TG+ S L +++ G + A + ++ Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106 Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277 S + G + VST + ++ M V ++ + +T+ A + Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166 Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337 S T T T + T T S AGS S ET+ TT + T+ Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226 Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSV-SVGALLPDAT----SSHRTVESGLE 1392 S+ G+ ET+ G+ ++ S +L P AT S TV Sbjct: 1227 SSAGS---------------ETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITAS 1271 Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440 A A S T + T +L Q + + P T TGT TA++ T++ Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 +S+ P + G ST G S + TS+ + TT ST +T ++ GP Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386 Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534 + +S P + P LQ + L+ +A V Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420 Score = 140 bits (353), Expect = 1e-32 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + TT T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 125 bits (313), Expect = 5e-28 Identities = 214/959 (22%), Positives = 337/959 (35%), Gaps = 105/959 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779 +A K TT+ T TT AS ++ T + G ++ ST TTT T Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856 Query: 780 QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836 + T++ S T TT + T+ T T+ T +++ Sbjct: 857 STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916 Query: 837 GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890 G T T T TVS T+ +G TT VTT+G+ T T Sbjct: 917 STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976 Query: 891 STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945 ST AG +T+ S A TT +I T+SS T ++ + +TT+T+ G Sbjct: 977 ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032 Query: 946 TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002 T T+T T + + + VS S TT TA T T++ SG G Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092 Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 G+ T S E TT++ TTT A+ G T V Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108 + + +T GS S ET T + TT S + S Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168 ET+ TT + T+ SS G+ + A G+ + I +T +LE S + +T Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSESTI---ASTASLEPTATSLTGSET 1263 Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215 S T S+T V+ S P+ M+ R G R A S Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1316 Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269 S V + +P + D A SH V +T+ + S++GA A + G + T Sbjct: 1317 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 160 bits (404), Expect = 2e-38 Identities = 287/1327 (21%), Positives = 469/1327 (35%), Gaps = 138/1327 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQ-----LSLPQELMAEAQAG--TTTLMVTGLTPEELAVT 1615 GS T T S + E + AG TTT +G T Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT 1229 Query: 1616 AAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQ 1675 + + +A +E A I + A A + EP TS + T ++A G Sbjct: 1230 GSETSTPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGA 1283 Query: 1676 EGQATTI 1682 +TT+ Sbjct: 1284 TAASTTV 1290 Score = 154 bits (390), Expect = 6e-37 Identities = 288/1320 (21%), Positives = 445/1320 (33%), Gaps = 169/1320 (12%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 + T +S+ GA D+ AA T +V+T E S + +T S T Sbjct: 560 GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 + T +T SS + G + Sbjct: 620 GSETTTAST------------------------------------TSSETTTASTEGSET 643 Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293 VST + V G R E GS +TTV+ T E + + T S Sbjct: 644 TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699 Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351 ET + TT T TTS GS S ET T + TT S G+ E Sbjct: 700 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756 Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384 G T TTS+ TTM+ +G+ + T + Sbjct: 757 TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 T V+ A S T A T A T S ET T + TT S SS Sbjct: 817 TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + ST+G TS+ TT +ST +TTV+ + + E Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564 + +L S + + E +E + + T S+ G ++ +AGS Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623 + T S S E + GT TT+ T + TA +E A Sbjct: 992 ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046 Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679 E + + + V TG T+ A TV+ + G +A + Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732 TT+ I T+ A V + A + T +++ I S Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 + AG+ +T + S T T S A S T A + A + T T +G E+ Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSET 1223 Score = 140 bits (353), Expect = 1e-32 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + TT T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 122 bits (306), Expect = 4e-27 Identities = 228/1027 (22%), Positives = 364/1027 (35%), Gaps = 108/1027 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAST-GPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG 782 +A K TT+ T TT AS ++ T + S + S T P +T +T ++ T+ Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTV---STAGSETIPASTAGSETTTTTS--TEGS 851 Query: 783 ATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842 T S+ G ++ TT S A I + A+ G + T Sbjct: 852 ETTTASTEGSET-----TTASTESSETTTATTIGSETTTASTEGSETTTT-------STE 899 Query: 843 GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVSTSLAGAGGH 900 G+ T G + T VS TT +G TT +T G+ TVST+ + Sbjct: 900 GSETTTASTEGSEITT---VSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956 Query: 901 STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960 S S T +TT+G+ T TA T + TT++ AG TT S Sbjct: 957 SAEGSETTTVTTMGSETT--------TASTAGSETTTVSTAGSETT------TASIEGSE 1002 Query: 961 TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV-QPGTVTLVCSNPPCE 1019 T + +G E V + T T TVT A S V G+ T S E Sbjct: 1003 TTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062 Query: 1020 THETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPP 1079 T TT + TTT ++ + + ST G + +V S Sbjct: 1063 TTTVSTTGSETTTA--------STADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1080 CETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRAC 1139 + E T +T +S S E TT + TT +S++G+ +A + Sbjct: 1115 TASTEGSEATTVSTTSSETT---TASTTGSEMTTVFTTVSETTTVSTIGS----EATTSS 1167 Query: 1140 AAGTPAVIRISVATGALEAAQGSKSQCQTRQTS-ATSTTMTVMATGAPCSAGPLLGPSMA 1198 AAG+ A + +T E S + +T S A S T T G+ + G Sbjct: 1168 AAGSEAT---TTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE-- 1222 Query: 1199 REPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAM--TRSSVGAGEPRMAP 1256 + A + S+ S + G + STA++ T +S+ E Sbjct: 1223 -----TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVS 1277 Query: 1257 VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS-------- 1308 + S + STTV+ T ++ + + P T TGT TA++S Sbjct: 1278 ITAS-GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1336 Query: 1309 -NAGSAQRVCSNPPCETHETGT-THTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTG 1366 A +A T GT T A++ TS G G + P + S G Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMG 1396 Query: 1367 T-TMSVS 1372 T T+S+S Sbjct: 1397 TNTVSMS 1403 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 160 bits (404), Expect = 2e-38 Identities = 287/1327 (21%), Positives = 469/1327 (35%), Gaps = 138/1327 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQ-----LSLPQELMAEAQAG--TTTLMVTGLTPEELAVT 1615 GS T T S + E + AG TTT +G T Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT 1229 Query: 1616 AAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQ 1675 + + +A +E A I + A A + EP TS + T ++A G Sbjct: 1230 GSETSTPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGA 1283 Query: 1676 EGQATTI 1682 +TT+ Sbjct: 1284 TAASTTV 1290 Score = 154 bits (390), Expect = 6e-37 Identities = 288/1320 (21%), Positives = 445/1320 (33%), Gaps = 169/1320 (12%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 + T +S+ GA D+ AA T +V+T E S + +T S T Sbjct: 560 GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 + T +T SS + G + Sbjct: 620 GSETTTAST------------------------------------TSSETTTASTEGSET 643 Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293 VST + V G R E GS +TTV+ T E + + T S Sbjct: 644 TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699 Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351 ET + TT T TTS GS S ET T + TT S G+ E Sbjct: 700 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756 Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384 G T TTS+ TTM+ +G+ + T + Sbjct: 757 TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 T V+ A S T A T A T S ET T + TT S SS Sbjct: 817 TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + ST+G TS+ TT +ST +TTV+ + + E Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564 + +L S + + E +E + + T S+ G ++ +AGS Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623 + T S S E + GT TT+ T + TA +E A Sbjct: 992 ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046 Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679 E + + + V TG T+ A TV+ + G +A + Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732 TT+ I T+ A V + A + T +++ I S Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 + AG+ +T + S T T S A S T A + A + T T +G E+ Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSET 1223 Score = 140 bits (353), Expect = 1e-32 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + TT T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 122 bits (306), Expect = 4e-27 Identities = 228/1027 (22%), Positives = 364/1027 (35%), Gaps = 108/1027 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAST-GPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG 782 +A K TT+ T TT AS ++ T + S + S T P +T +T ++ T+ Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTV---STAGSETIPASTAGSETTTTTS--TEGS 851 Query: 783 ATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842 T S+ G ++ TT S A I + A+ G + T Sbjct: 852 ETTTASTEGSET-----TTASTESSETTTATTIGSETTTASTEGSETTTT-------STE 899 Query: 843 GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVSTSLAGAGGH 900 G+ T G + T VS TT +G TT +T G+ TVST+ + Sbjct: 900 GSETTTASTEGSEITT---VSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956 Query: 901 STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960 S S T +TT+G+ T TA T + TT++ AG TT S Sbjct: 957 SAEGSETTTVTTMGSETT--------TASTAGSETTTVSTAGSETT------TASIEGSE 1002 Query: 961 TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV-QPGTVTLVCSNPPCE 1019 T + +G E V + T T TVT A S V G+ T S E Sbjct: 1003 TTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062 Query: 1020 THETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPP 1079 T TT + TTT ++ + + ST G + +V S Sbjct: 1063 TTTVSTTGSETTTA--------STADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1080 CETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRAC 1139 + E T +T +S S E TT + TT +S++G+ +A + Sbjct: 1115 TASTEGSEATTVSTTSSETT---TASTTGSEMTTVFTTVSETTTVSTIGS----EATTSS 1167 Query: 1140 AAGTPAVIRISVATGALEAAQGSKSQCQTRQTS-ATSTTMTVMATGAPCSAGPLLGPSMA 1198 AAG+ A + +T E S + +T S A S T T G+ + G Sbjct: 1168 AAGSEAT---TTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE-- 1222 Query: 1199 REPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAM--TRSSVGAGEPRMAP 1256 + A + S+ S + G + STA++ T +S+ E Sbjct: 1223 -----TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVS 1277 Query: 1257 VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS-------- 1308 + S + STTV+ T ++ + + P T TGT TA++S Sbjct: 1278 ITAS-GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1336 Query: 1309 -NAGSAQRVCSNPPCETHETGT-THTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTG 1366 A +A T GT T A++ TS G G + P + S G Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMG 1396 Query: 1367 T-TMSVS 1372 T T+S+S Sbjct: 1397 TNTVSMS 1403 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] Length = 1531 Score = 160 bits (404), Expect = 2e-38 Identities = 287/1327 (21%), Positives = 469/1327 (35%), Gaps = 138/1327 (10%) Query: 419 SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478 S + +P+P + + ++ IT A T ++ T + S T + Sbjct: 39 STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98 Query: 479 RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537 + +TG + T + + + + + TVTS V T ++ T Sbjct: 99 TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158 Query: 538 -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588 ++ +G A ++ I PS+A TV + + TT V T T TT Sbjct: 159 TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 +T ++ T + TA ++ T+VS+A + +T ++ T Sbjct: 216 TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273 Query: 649 VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708 + G T + S + S +G ++ T +T+ V+ AS+ T Sbjct: 274 TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 + A T+ G TT ++TT T +I+G + + STT TTT Sbjct: 327 FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826 + + G+ T S T+ T T+ T +TAV T Sbjct: 377 STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436 Query: 827 QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885 +++ + T T G T T S K A TT TT + G Sbjct: 437 STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944 T TV T + ST S T ++ G+ + T+S++ T ++ + ++TT + GL Sbjct: 492 ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004 T T + + T T +G E A+ T T TV+ ADS Sbjct: 552 ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606 Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 + T S ET TT++ TTT A+ G T ++ ++V++T Sbjct: 607 STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 GS + S ET T + TT ++ +G S ET + TT + TT Sbjct: 660 -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 S+ G+ T ++ T + E ++ + + + +T++ STT + T Sbjct: 715 TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243 + S+ + M E S S ++S+ S K + + A+ T Sbjct: 765 ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818 Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303 S + + GS +TT T T S T T T T ++ Sbjct: 819 ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872 Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349 T T + GS S ET T T + TT S G T EG + Sbjct: 873 TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932 Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402 A T ST + +++V A + T+ S T S G E + + Sbjct: 933 TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992 Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462 TA + T V S+ ET TT T TT+TS S A + T G Sbjct: 993 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051 Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510 TS+ + TTTVS+T + T T T ST G + + + G Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562 + + S +T + S+E +AS T + +S+ G ++ +A Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169 Query: 1563 GSAVVATVVVQPPPPTQSEVDQ-----LSLPQELMAEAQAG--TTTLMVTGLTPEELAVT 1615 GS T T S + E + AG TTT +G T Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT 1229 Query: 1616 AAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQ 1675 + + +A +E A I + A A + EP TS + T ++A G Sbjct: 1230 GSETSTPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGA 1283 Query: 1676 EGQATTI 1682 +TT+ Sbjct: 1284 TAASTTV 1290 Score = 154 bits (390), Expect = 6e-37 Identities = 288/1320 (21%), Positives = 445/1320 (33%), Gaps = 169/1320 (12%) Query: 543 MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596 MS +A AA + T S T+L + TT T TP T T+ Sbjct: 1 MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654 S + + T + G+ ++A+ + ++ S T TV+ T V + Sbjct: 61 SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120 Query: 655 GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708 G T T + S +V + +S +G + T +T+A TG T T Sbjct: 121 GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180 Query: 709 IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768 +T P AG+ V++A + TT+ TT G+ T S + ++T TT Sbjct: 181 GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236 Query: 769 IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828 + T ++ AG+ +S T T T+ TA TG Sbjct: 237 VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886 ++ + G T+ T+ + VS VTT+ G T +T+G+ Sbjct: 291 --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342 Query: 887 TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVST+ G +T+AS+ +T TT T S++ T + ++ T + Sbjct: 343 TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398 Query: 942 GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T T+++ T T E + + ++ + T + +TIA + Sbjct: 399 TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450 Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 + G+ T + ET TT + TTT A+ G T D A+ Sbjct: 451 SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 +T GS + S E TT + TT S ET T T Sbjct: 509 EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559 Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 + T +S+ GA D+ AA T +V+T E S + +T S T Sbjct: 560 GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 + T +T SS + G + Sbjct: 620 GSETTTAST------------------------------------TSSETTTASTEGSET 643 Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293 VST + V G R E GS +TTV+ T E + + T S Sbjct: 644 TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699 Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351 ET + TT T TTS GS S ET T + TT S G+ E Sbjct: 700 SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756 Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384 G T TTS+ TTM+ +G+ + T + Sbjct: 757 TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 T V+ A S T A T A T S ET T + TT S SS Sbjct: 817 TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + ST+G TS+ TT +ST +TTV+ + + E Sbjct: 874 TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564 + +L S + + E +E + + T S+ G ++ +AGS Sbjct: 934 TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623 + T S S E + GT TT+ T + TA +E A Sbjct: 992 ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046 Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679 E + + + V TG T+ A TV+ + G +A + Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103 Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732 TT+ I T+ A V + A + T +++ I S Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163 Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790 + AG+ +T + S T T S A S T A + A + T T +G E+ Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSET 1223 Score = 140 bits (353), Expect = 1e-32 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%) Query: 681 GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737 G + T +T+ + +AS T T +T P P G+ +V+ + + TT T Sbjct: 12 GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71 Query: 738 -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 T ++G+GT + S + ST TTT+ T + +++ G+ T+S Sbjct: 72 GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128 Query: 793 KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T + +TS G+ ++ V + T + T A G+ + TV Sbjct: 129 ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911 G +TP T + V+T + TT V+T G+ T T ST+ + ST S T ++ Sbjct: 180 AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971 T G+ T+S+ TA + ++T T T + T + P+ Sbjct: 239 TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298 Query: 972 QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 S + TT+ TA+ + G+ T+ S ET TT + TT Sbjct: 299 MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 T A++ G T + A+ +T GS S ET T++ Sbjct: 355 T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 TT T E TT TT S+ G+ I I+ Sbjct: 413 TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 + + ++ T T+A S T T TG+ + Sbjct: 448 TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 +S L + ++ + G + ST ++V A M V GS +TTV+ Sbjct: 486 ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537 Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331 T E T T T TTS GS S ET T Sbjct: 538 TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580 Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + TTA S G+ +TT+ T S + A D+ ++ + +G Sbjct: 581 SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 E A + + + TA T V S ET TT + T+TS S A Sbjct: 622 ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510 + V + + ++ + + TT VS+T + TT T+ + + S+ E S G Sbjct: 681 SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565 + ++ S + G S + + A++ ++ST + + S S+ Sbjct: 741 ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800 Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619 + TV + T SE +S E + + AG+ T T E + Sbjct: 801 KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860 Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679 + A+TE ++ + A E TS + T A S EG E Sbjct: 861 SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739 I V T + + A + L T + ++++ A G+ Sbjct: 913 --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961 Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793 +TV + S T T S A S T + A ++ + T T + G E+ V Sbjct: 962 ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016 Score = 122 bits (306), Expect = 4e-27 Identities = 228/1027 (22%), Positives = 364/1027 (35%), Gaps = 108/1027 (10%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 A+T E + V TA S T A+ T V ++ ++ + + Sbjct: 456 ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513 Query: 435 PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494 AV T+ + + +TT TV + + T + + TG + Sbjct: 514 TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573 Query: 495 TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554 TT + + A+ + T S T ++ T ++ + A+ ++ Sbjct: 574 TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633 Query: 555 ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 T S TV + + TT+V +T+ T G+ T TV S VS + Sbjct: 634 TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690 Query: 609 MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667 GT+ S T + T + T T T + +++ T ++ G T T + S Sbjct: 691 ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAST-GPVTQIIQTKGPLPAGTILKLVT 726 + + T TS+ T AS G T + T G+ V+ Sbjct: 742 TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796 Query: 727 SADGKPTTIIT----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG 782 +A K TT+ T TT AS ++ T + S + S T P +T +T ++ T+ Sbjct: 797 TASSKMTTVFTENSETTIASTTASETTTV---STAGSETIPASTAGSETTTTTS--TEGS 851 Query: 783 ATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842 T S+ G ++ TT S A I + A+ G + T Sbjct: 852 ETTTASTEGSET-----TTASTESSETTTATTIGSETTTASTEGSETTTT-------STE 899 Query: 843 GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVSTSLAGAGGH 900 G+ T G + T VS TT +G TT +T G+ TVST+ + Sbjct: 900 GSETTTASTEGSEITT---VSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956 Query: 901 STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960 S S T +TT+G+ T TA T + TT++ AG TT S Sbjct: 957 SAEGSETTTVTTMGSETT--------TASTAGSETTTVSTAGSETT------TASIEGSE 1002 Query: 961 TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV-QPGTVTLVCSNPPCE 1019 T + +G E V + T T TVT A S V G+ T S E Sbjct: 1003 TTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062 Query: 1020 THETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPP 1079 T TT + TTT ++ + + ST G + +V S Sbjct: 1063 TTTVSTTGSETTTA--------STADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114 Query: 1080 CETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRAC 1139 + E T +T +S S E TT + TT +S++G+ +A + Sbjct: 1115 TASTEGSEATTVSTTSSETT---TASTTGSEMTTVFTTVSETTTVSTIGS----EATTSS 1167 Query: 1140 AAGTPAVIRISVATGALEAAQGSKSQCQTRQTS-ATSTTMTVMATGAPCSAGPLLGPSMA 1198 AAG+ A + +T E S + +T S A S T T G+ + G Sbjct: 1168 AAGSEAT---TTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE-- 1222 Query: 1199 REPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAM--TRSSVGAGEPRMAP 1256 + A + S+ S + G + STA++ T +S+ E Sbjct: 1223 -----TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVS 1277 Query: 1257 VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS-------- 1308 + S + STTV+ T ++ + + P T TGT TA++S Sbjct: 1278 ITAS-GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1336 Query: 1309 -NAGSAQRVCSNPPCETHETGT-THTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTG 1366 A +A T GT T A++ TS G G + P + S G Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMG 1396 Query: 1367 T-TMSVS 1372 T T+S+S Sbjct: 1397 TNTVSMS 1403 Score = 47.4 bits (111), Expect = 1e-04 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%) Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423 S+ TT++ + G+ A+++ + L A+ + AG+ P PT + Sbjct: 2 SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 E TT TA + + +SS A S G ++++ + TTTVS T T Sbjct: 62 GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 + S E S + + +TA +S +++ E+ Sbjct: 115 TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174 Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601 S T PS+ + A T SE S E A + G+ T Sbjct: 175 TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 V+ E TA +E AA+TE+++ T D+ A+ Sbjct: 235 TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277 Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721 T E S G E T + ++ +A+ + + + + A + + T A ++ Sbjct: 278 TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332 Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779 ++ + S G+ +T +++ S T+T+S S T A + A + + Sbjct: 333 TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392 Query: 1780 TLTEVANGIESLGV 1793 T G E+ V Sbjct: 393 ATTVSTTGSETTTV 406 >gi|161019170 mucin 5AC [Homo sapiens] Length = 6207 Score = 149 bits (376), Expect = 3e-35 Identities = 358/1587 (22%), Positives = 554/1587 (34%), Gaps = 273/1587 (17%) Query: 361 TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV 420 T + PP +V A T ++ S +++ L PA +TAT+PT V + Sbjct: 2622 TLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATAL-----PALRSTATTPTATSVTPI 2676 Query: 421 PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPP-TTTTIQVLPTVPGSSISVPTAAR 479 P++ + + T T P + P T+T + T G++ SV T + Sbjct: 2677 PSSSLGTTWTRLSQTTTPTATMS--TATPSSTPETAHTSTVLTATATTTGATGSVATPSS 2734 Query: 480 TQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAP-----VTVTSLPAGVRMVVPTQSAQG 534 T G KV TT T T P+S G A ++ T+ P V S G Sbjct: 2735 TPGTAHTTKVP----TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG 2790 Query: 535 TVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPA--- 591 T ++ + +A + AT PSS+ + TMA T G + P+ Sbjct: 2791 TTHTATVLTTTTTTVATGSMAT----PSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPH 2846 Query: 592 TVKVA----SSPVM----VSNPATRMLKTAAAQVGTSV-----------SSATNTS---- 628 TV+ A +S ++ ++ P+T T AA GT+ SS T S Sbjct: 2847 TVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSP 2906 Query: 629 --TRPIITVHKSGTVTVAQQAQVVTTVV-------GGVTKTITLVKSP-----------I 668 T P T S T A ++ T+ + +T +T+ P Sbjct: 2907 GTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSY 2966 Query: 669 SVPGGSA----LISNLGKVMSVVQTKPVQTSAVTGQASTG-PVTQIIQT-KGPLPAGTIL 722 +PG S SN+ V +P+ QA G P+ ++ Q + L G + Sbjct: 2967 PMPGPSGGDFDTYSNIRAAGGAVCEQPLGLEC-RAQAQPGVPLRELGQVVECSLDFGLVC 3025 Query: 723 KLVTSADGKPTTIIT---TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIIT 779 + GK G P+ SS + ++ PGTT I+ + +A T Sbjct: 3026 RNREQV-GKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTT 3084 Query: 780 QAGATGVTSSPGIKSPITII-----TTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVV 834 ++ TG T++P T I TT +T TG+ A + T H T Sbjct: 3085 ES--TGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT 3142 Query: 835 LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVT-GTVSTS 893 + + P + +P T +A+ +T T T + + + GT T Sbjct: 3143 VTSSKATPFS-------------SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTR 3189 Query: 894 LAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQP 953 L+ + + S ATP +T T+ T S V+ TA TT A G + TP+ T P Sbjct: 3190 LSQTTTPTATMSTATPSSTPETVHT--STVLTTTA-------TTTGATGSVATPSST--P 3238 Query: 954 VSQPTQVTLITAPSGVEAQP------VHDLPVSILASPTTEQPTATVTIADSGQGDVQPG 1007 + T L T +G A P LPV I + T +TVT P Sbjct: 3239 GTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVT----------PS 3288 Query: 1008 TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQ 1067 ++ P TH T T T TTT VA G P+ V +T Sbjct: 3289 SI-------PGTTH-TPTVLTTTTTTVAT-GSMATPSSSTQTSGTTHTPP--VPNTTATT 3337 Query: 1068 NGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSV 1127 +G + S T T T+ T G S+ P T TGTT +T A+SS Sbjct: 3338 HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT--TGTTQHSTPALSSP 3395 Query: 1128 -GANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT----RQTSATSTTMTVMA 1182 ++ ++ + TP R + T A A SK++ T TSA TT+ M Sbjct: 3396 HPSSRTTESPPSPGTTTPGHTRATSRTTA--TATPSKTRTSTLLPSSPTSAPITTVVTMG 3453 Query: 1183 TGAPCS-------AGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSH 1235 C+ + P+ GPS GG + S +R + ++ + P G Sbjct: 3454 CEPQCAWSEWLDYSYPMPGPS-----GGDFDTY-------SNIRAAGGAVCEQPLGLECR 3501 Query: 1236 AVSTAAMTRSSVG------------------AGEPRM--------------------APV 1257 A + + +G G+ +M A Sbjct: 3502 AQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS 3561 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATV--------TQVCSNPPCETHETGTTNTATTSN 1309 + +P TT +T +AT T + PP T TT TAT+S Sbjct: 3562 STATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSK 3621 Query: 1310 A--GSAQRVCSNPPCETHETGTTHTATTAT-----SNGGTGQ-PEGGQQP--------PA 1353 A S+ R + P T T T TAT+ T + G TG PE P P+ Sbjct: 3622 ATSSSSPRTATTLPVLT-STATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPS 3680 Query: 1354 GRPCETH-------QTTSTGTTMSVSVGALLPDAT--SSHRTVESGLEVAAAPSVTPQA- 1403 P TH + T+T T S+S + P T + T + A P+ TP + Sbjct: 3681 STPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSST 3740 Query: 1404 -GTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSN-MSSNQDPPPAASDQGEVESTQG 1461 GT + P+ P + T ++ AT T ++S P S + S+ G Sbjct: 3741 PGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPG 3800 Query: 1462 DSVNITSSSAITTTVSSTLTRAVTTV---TQSTPVPGPSVPPPEELQVSPGPRQQLPPRQ 1518 + + + + TT ++T A+ + T T + + P +P + Sbjct: 3801 TATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTS 3860 Query: 1519 LLQSASTALMGESAEVLSASQTP------ELPAAVDLSSTGEPSSGQESAGSAVVATVVV 1572 + + +T + V + S TP ++P T PSS +A + V Sbjct: 3861 TVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTT 3920 Query: 1573 QPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQA 1632 P S V S+P T T++ T T A ++ Q + T Sbjct: 3921 TTPTTRGSTVTPSSIP------GTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPP 3974 Query: 1633 LAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELA 1692 + + + + T+ +AT H+ T P +T A Sbjct: 3975 VPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI----------TEPSTVTSHTPA 4024 Query: 1693 ALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPS-TA 1751 A Q H T P+ P GT +T PS T Sbjct: 4025 ATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTP-------GHTRGTSRTTATATPSKTR 4077 Query: 1752 TESLAPSNTFVAPQPVVVASPAKLQAA 1778 T +L PS+ AP VV + + Q A Sbjct: 4078 TSTLLPSSPTSAPITTVVTTGCEPQCA 4104 Score = 142 bits (359), Expect = 3e-33 Identities = 342/1437 (23%), Positives = 489/1437 (34%), Gaps = 187/1437 (13%) Query: 404 ATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPA----PPTTT 459 +T T T+ T SV A P +P A V T G T P ++P PP Sbjct: 3860 STVLTTTTTTTRATGSV-ATPSSTPGTAHTTK-VPTTTTTGFTATPSSSPGTALTPPVWI 3917 Query: 460 TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSL 519 + PT GS+++ + T VL T TG S A + T TS Sbjct: 3918 STTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG---------SMATPSSSTQTS- 3967 Query: 520 PAGVRMVVPTQSAQGTVIGSS-PQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVK 578 G P + T G S P S A +AT I ++ T S T Sbjct: 3968 --GTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAA 4025 Query: 579 TMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKS 638 T + T +T PA S +P + T GTS ++AT T ++ + Sbjct: 4026 TTSTTQHST--PALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLP 4083 Query: 639 GTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSA----LISNLGKVMSVVQTKPVQT 694 + T A VVTT + +PG S SN+ V +P+ Sbjct: 4084 SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGL 4143 Query: 695 SAVTGQASTG-PVTQIIQT-KGPLPAGTILKLVTSADGKPTTIIT---TTQASGAGTKPT 749 QA G P+ ++ Q + L G + + GK G P+ Sbjct: 4144 EC-RAQAQPGVPLRELGQVVECSLDFGLVCRNREQV-GKFKMCFNYEIRVFCCNYGHCPS 4201 Query: 750 ILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTG 809 SS + ++ PGTT I+ + +A T++ TG T++P T I T+ T Sbjct: 4202 TPATSSTATPSSTPGTTWILTKLTTTATTTES--TGSTATPSSTPGTTWILTEPST---- 4255 Query: 810 APAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAV 869 TA + TG + G P T T P TP + A+ Sbjct: 4256 ------TATVTVPTGSTATASSTQATAGTPHVSTTA--TTPTVTSSKATPFSSPGTATAL 4307 Query: 870 TTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAI 929 L TT T T + S T+ A T+ T S+ T+ Sbjct: 4308 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA----TMSTATPSSTPETAHTST 4363 Query: 930 TVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQ 989 ++ TT A G + TP+ T P + T T +G P P + P Sbjct: 4364 VLTTTATTTRATGSVATPSST--PGTAHTTKVPTTTTTGFTVTP-SSSPGTARTPPVWIS 4420 Query: 990 PTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 T T T + S T+ S+ P TH T T T TTT VA G P+ Sbjct: 4421 TTTTPTTSGS----------TVTPSSVPGTTH-TPTVLTTTTTTVAT-GSMATPSSSTQT 4468 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPC 1109 V +T +G + S T T T+ T G S+ P Sbjct: 4469 SGTTHTPP--VPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 4526 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT- 1168 T TGTT +T A+SS + R + GT + + A SK++ T Sbjct: 4527 AT--TGTTQHSTPALSSPHPS-SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTL 4583 Query: 1169 ---RQTSATSTTMTVMATGAPCS-------AGPLLGPSMAREPGGRSPAFVQLAPLSSKV 1218 TSA TT+ C+ + P+ GPS GG + S + Sbjct: 4584 LPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS-----GGDFDTY-------SNI 4631 Query: 1219 RLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL 1278 R + ++ + P G + A + V GE C SL G + Sbjct: 4632 RAAGGAVCEQPLG-----LECRAQAQPGVPLGELGQVVEC-SLDFGLVCRNREQVG-KFK 4684 Query: 1279 LCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATS 1338 +C + + C N T++TA S S P T T TATT S Sbjct: 4685 MCFNYEIRVFCCNYGHCPSTPATSSTAMPS---------STPGTTWILTELTTTATTTAS 4735 Query: 1339 NGGTGQPEG--GQQPP---AGRPCETHQTTSTGTTMSVS--VGALLPDATSSHRTVESGL 1391 G T P G PP P T TS+ T S S LP TS+ T + Sbjct: 4736 TGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTST-ATKSTAT 4794 Query: 1392 EVAAAPSVT-------PQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 V PS T P+ T +A T S P TTHT+T +T+ ++ + Sbjct: 4795 SVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPE-------TTHTSTVLTTKATTTR 4847 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 A S ST G TT + + LT A TT + P PS Sbjct: 4848 ----ATSSTSTPSSTPG-----------TTWILTELTTAATTTAATGPTATPS------- 4885 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQT------PELPAAVDL--SSTGEPS 1556 +PG L + +TA G +A S T P A V + ST S Sbjct: 4886 -STPGTTWIL-TELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS 4943 Query: 1557 SGQESAGSAVVATVVVQP------PPPTQSEVDQLSLPQELMAEAQAGTTTLMVT----- 1605 S Q +AG+ V+T P P+ S +LP L + A T T Sbjct: 4944 STQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALP-ALRSTATTPTATSFTAIPSSS 5002 Query: 1606 -GLTPEELAVTAAAEAA-AQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVT 1663 G T L+ T A + A + + + VL A TG S T Sbjct: 5003 LGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAH 5062 Query: 1664 QAELGHLSAEGQEGQATTIP-IVLTQQELAALVQQQQLQEAQAQQQHH--HLPTEALAPA 1720 ++ + G ++ P LT + + + + H + T Sbjct: 5063 TTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMT 5122 Query: 1721 DSLNDPAIESN------CLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVAS 1771 + N A S+ L EL T +T A STAT S P T++ +P +A+ Sbjct: 5123 RATNSTATPSSTLGTTRILTELT-TTATTTAATGSTATLSSTPGTTWILTEPSTIAT 5178 Score = 141 bits (356), Expect = 6e-33 Identities = 277/1167 (23%), Positives = 406/1167 (34%), Gaps = 199/1167 (17%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP------P 456 P+T AT+++ TP+ P K A + G T P + P P Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTEST------GSTATPSSTPGTTWILTEP 4253 Query: 457 TTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTV 516 +TT +PT GS+ + + T G P V T TP VT A+ +P T Sbjct: 4254 STTATVTVPT--GSTATASSTQATAGTPHV------STTATTPTVTSSKATPFS-SPGTA 4304 Query: 517 TSLPAGVRMVVPTQSAQG-TVIGSSPQMSGMAALAAAAAATQKIP---PSSAP------T 566 T+LPA +R T +A T I SS + L+ T + PSS P T Sbjct: 4305 TALPA-LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTST 4363 Query: 567 VLSVPAGTT----IVKTMAVTPGT---------TTLPATVKVASSPVMVSNP----ATRM 609 VL+ A TT V T + TPGT TT TV +SSP P +T Sbjct: 4364 VLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTT 4423 Query: 610 LKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS 669 T + T S T T ++T + T + +T G T T + + + Sbjct: 4424 TPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTAT 4483 Query: 670 VPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSAD 729 G S S+ V + TSA +G T +T+ PA T T Sbjct: 4484 THGRSLSPSSPHTV------RTAWTSATSGTLGTTHITEPSTGTSHTPAAT-----TGTT 4532 Query: 730 GKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSS 789 T +++ S T+ S SP TT PG TT +A ++ + + S Sbjct: 4533 QHSTPALSSPHPSSRTTE------SPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS 4586 Query: 790 PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG------------ 837 +PIT + T + + P G + Sbjct: 4587 SPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLE 4646 Query: 838 --APGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLA 895 A QPG VP+G + V ++ LV + V Sbjct: 4647 CRAQAQPG-----VPLGELGQVVECSLDF------GLVCRNREQVGKFKMCFNYEIRVFC 4695 Query: 896 GAGGHSTS----ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITM 951 GH S +S A P +T GT L T +T +A TT + G TP+ T Sbjct: 4696 CNYGHCPSTPATSSTAMPSSTPGTTWIL-------TELTTTA--TTTASTGSTATPSSTP 4746 Query: 952 QPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTL 1011 P ++T+P+ P + + T+ T T T T Sbjct: 4747 GTAPPPK---VLTSPATT--------PTATSSKATSSSSPRTATTLPVLTSTATKSTATS 4795 Query: 1012 VCSNPPCETHETGTTNTATTTVVANLGG-HPQPTQVQFVCDRQEAAASLVTSTVGQQNGS 1070 V P TGT TTT VA + HP T + TSTV + Sbjct: 4796 VTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTP-----------ETTHTSTVLTTKAT 4844 Query: 1071 VVRVCSNPPCETHETGTT---NTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSV 1127 R S+ + GTT TTA + A G + P T T T T ++ Sbjct: 4845 TTRATSSTSTPSSTPGTTWILTELTTAATTTAAT-GPTATPSSTPGTTWILTELTTTATT 4903 Query: 1128 GANHQRDARRACAAGTPAVIR-------ISVATGALEAAQGSKSQCQTRQTSATSTTMTV 1180 A+ A + GT ++ ++V TG+ A +++ T S T+TT TV Sbjct: 4904 TASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 4963 Query: 1181 MATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTA 1240 ++ A S+ P ++ P RS A ++P+ A S Sbjct: 4964 TSSKATPSSSPGTATAL---PALRSTA-------------TTPT-----------ATSFT 4996 Query: 1241 AMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETG 1300 A+ SS+G R+ S T T TA + PS+T V ++ T Sbjct: 4997 AIPSSSLGTTWTRL------------SQTTTPTATMSTATPSSTPETVHTS-------TV 5037 Query: 1301 TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH 1360 T TATT+ A + S+ P H T T TT + + P PP P T Sbjct: 5038 LTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTM 5097 Query: 1361 QTTSTGTTMS-------VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPT 1413 T T +T ++ A + AT+S T S L + T A T Sbjct: 5098 STIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGST 5157 Query: 1414 QRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAIT 1473 + S P GTT T S +++ P + + T +T+ + + Sbjct: 5158 ATLSSTP-------GTTWILTE-PSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMP 5209 Query: 1474 TTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 T +ST+ + T T TP PS P Sbjct: 5210 TATASTVPSSSTVGTTRTPAVLPSSLP 5236 Score = 133 bits (335), Expect = 2e-30 Identities = 342/1587 (21%), Positives = 525/1587 (33%), Gaps = 284/1587 (17%) Query: 392 SYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQA 451 +++L Q TA T ++ P+ P A PPK A P + Sbjct: 3573 TWILTEQTTAATTTATTGSTAIPSSTPGT-APPPKVLTSTATTPTATSSKAT-------S 3624 Query: 452 APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPA-VLKVTG--PQATTGTPLVTMRPASQ 508 + +P T TT+ VL + S TA +P+ L TG P+ TT TP+ TM Sbjct: 3625 SSSPRTATTLPVLTSTATKS----TATSFTPIPSFTLGTTGTLPEQTT-TPMATMSTIHP 3679 Query: 509 AGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTV 567 + T TS + ++ + S+P + + L AA T P++ P+ Sbjct: 3680 SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPS- 3738 Query: 568 LSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT 627 S P GTT + T T T T+P T A++ + T + T+ A T +SS Sbjct: 3739 -STP-GTTWILTEPSTTATVTVP-TGSTATASSTRATAGTLKVLTSTATTPTVISSRATP 3795 Query: 628 STRP--IITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685 S+ P + + A VT + T S + P + + Sbjct: 3796 SSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPE 3855 Query: 686 VVQTKPVQTSAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTSADGKPTTIITTTQ 740 V T V T+ T +TG V T G +P T + P T +T Sbjct: 3856 TVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPV 3915 Query: 741 ASGAGTKPTILGISSVSPSTTKPGTT-------TIIKTIPMSAIITQAGAT---GVTSSP 790 T PT G S+V+PS+ PGTT T T+ ++ T + +T G T +P Sbjct: 3916 WISTTTTPTTRG-STVTPSSI-PGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTP 3973 Query: 791 GIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVP 850 + P T TT + +P + TA +G G T + +P T+ P Sbjct: 3974 PV--PNTTATTHGRSLPPSSPHTVRTAWTSATSGI--LGTTHIT------EPSTVTSHTP 4023 Query: 851 MGGVRLVTPVT--VSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASL-- 906 T +S+ P+ T + G TT G GT T+ + +++L Sbjct: 4024 AATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLP 4083 Query: 907 ----ATPITTLGTIAT-----------LSSQVINPTAITVSAAQTTLTAAGGLTTPTITM 951 + PITT+ T S + P+ A G + + + Sbjct: 4084 SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGL 4143 Query: 952 Q---------PVSQPTQVTLITAPSGV---------EAQPVHDLPVSILAS-----PTTE 988 + P+ + QV + G+ + + + + + P+T Sbjct: 4144 ECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTP 4203 Query: 989 QPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQ-VQ 1047 ++T T + + PGT ++ T T TATTT P T Sbjct: 4204 ATSSTATPSST------PGTTWIL----------TKLTTTATTTESTGSTATPSSTPGTT 4247 Query: 1048 FVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNP 1107 ++ A++ T S + + P T TT T T++ + G + Sbjct: 4248 WILTEPSTTATVTVPTGSTATASSTQATAGTP-HVSTTATTPTVTSSKATPFSSPGTATA 4306 Query: 1108 PCETHETGTTNTATT----AMSSVGANHQRDARR---------ACAAGTPAVIRISVA-- 1152 T TT TAT+ SS+G R ++ A + TP S Sbjct: 4307 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLT 4366 Query: 1153 -TGALEAAQGS----KSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPA 1207 T A GS S T T+ TT T T P S+ P AR P P Sbjct: 4367 TTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSS-----PGTARTP----PV 4417 Query: 1208 FVQLA--PLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGS 1265 ++ P +S ++ S+ P H+ V T T + G+ MA S Q Sbjct: 4418 WISTTTTPTTSGSTVTPSSV---PGTTHTPTVLTTTTTTVATGS----MATPSSSTQTSG 4470 Query: 1266 PSTTVTVTALEALLCPSATVT-QVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCET 1324 + T V P+ T T S P H T T+ TS + + P T Sbjct: 4471 TTHTPPV--------PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI-TEPSTGT 4521 Query: 1325 HETGTTHTATTATSNGGTGQPEGG----QQPPA------GRPCETHQTTSTGTTMSVSVG 1374 T T TT S P + PP+ G T +TT+T T Sbjct: 4522 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS 4581 Query: 1375 ALLPDATSSH---RTVESGLEVAAAPS----------------------VTPQAGTALLA 1409 LLP + +S V +G E A S + G Sbjct: 4582 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ 4641 Query: 1410 PFPTQ-RVCSNPPCETHETGTTHTATT----VTSN--------MSSNQDPPPAASDQGEV 1456 P + R + P E G + V N M N + + G Sbjct: 4642 PLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC 4701 Query: 1457 ESTQGDSVNITSSSA-----ITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPR 1511 ST S SS I T +++T T +T + +TP P PP ++ SP Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4761 Query: 1512 QQLPPRQLLQSAS-------TALMGESAEVLSASQTP--------------ELPAAVDLS 1550 + S+S L + + + S TP + V Sbjct: 4762 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4821 Query: 1551 STGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE--LMAEAQAGTTTLMVTGLT 1608 ST PSS E+ ++ V T T S S P ++ E TT TG T Sbjct: 4822 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4881 Query: 1609 P------------EELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTS 1656 EL TA A+ + AT + + + + A + T T+ Sbjct: 4882 ATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATV-TVPTGSTA 4940 Query: 1657 EAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEA 1716 A++T A H+S T P V + + T + Sbjct: 4941 TASSTQATAGTPHVST------TATTPTVTSSK-----------------------ATPS 4971 Query: 1717 LAPADSLNDPAIESNCLNELAGT---VPS-----TVALLPSTATESLAPSNTFVAPQPVV 1768 +P + PA+ S A + +PS T L T T + S + P Sbjct: 4972 SSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET 5031 Query: 1769 VASPAKLQAAATLTEVANGIESLGVKP 1795 V + L A AT T + + P Sbjct: 5032 VHTSTVLTATATTTGATGSVATPSSTP 5058 Score = 130 bits (328), Expect = 1e-29 Identities = 242/1110 (21%), Positives = 389/1110 (35%), Gaps = 126/1110 (11%) Query: 590 PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQV 649 P+T +S+ + S P T + T T+ S +T+T P T + +T Sbjct: 3053 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTAT-PSSTPGTTWILTEPSTTAT 3111 Query: 650 VTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI 709 VT G T T + ++ P V + T V +S T +S G T + Sbjct: 3112 VTVPTGS-TATASSTQATAGTP----------HVSTTATTPTVTSSKATPFSSPGTATAL 3160 Query: 710 IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTII 769 + T TS P++ + TT + T +S+ +PS+T T+ Sbjct: 3161 PALRSTATTPT----ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE---TVH 3213 Query: 770 KTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQ-- 827 + ++ T GATG ++P +P T TTKV+T+ T TA P + G + Sbjct: 3214 TSTVLTTTATTTGATGSVATPS-STPGTAHTTKVLTTTTTG----FTATPSSSPGTARTL 3268 Query: 828 ----QGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883 T +G+ P +I T V T TV+ A + + T+G T Sbjct: 3269 PVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQ-TSGTTHT 3327 Query: 884 GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG- 942 V T +T+ H S S ++P T + +S + T IT + T+ T A Sbjct: 3328 PPVPNTTATT------HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 3381 Query: 943 -GLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001 G T + P+ T + PS P H S + T T T T+ S Sbjct: 3382 TGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSP 3441 Query: 1002 GDVQPGTVTLVCSNPPCETHET------------GTTNTATTTVVANLGGHPQPTQVQFV 1049 TV + P C E G +T + A QP ++ Sbjct: 3442 TSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECR 3501 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPP----------------CETHETGTTNTATT 1093 Q V + + VC N C + + AT+ Sbjct: 3502 AQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS 3561 Query: 1094 ATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVAT 1153 +T+ + G + E T T TATT +++ ++ GT ++ +T Sbjct: 3562 STATPSSTPGTTWILTE-QTTAATTTATTGSTAIPSS---------TPGTAPPPKVLTST 3611 Query: 1154 GALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAP 1213 A SK+ + + T+TT+ V+ + A S P + G Q Sbjct: 3612 ATTPTATSSKATSSS--SPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTT 3669 Query: 1214 LSSKVRLSSPSIKDLPAGRHSHAVST--AAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 + + PS P H+ V T A TR++ P P + + T Sbjct: 3670 PMATMSTIHPS--STPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3727 Query: 1272 VTALEALLCPSAT--VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGT 1329 A PS+T T + + P T T T T +T+ A S + Sbjct: 3728 TAATGPTATPSSTPGTTWILTEP--STTATVTVPTGSTATASSTRATAGTLKV------L 3779 Query: 1330 THTATTATSNGGTGQPEGGQQPPAGRPC-ETHQTTSTGTTMSVSVGALLPDATS--SHRT 1386 T TATT T P P + TT T T+++ + L A + S T Sbjct: 3780 TSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3839 Query: 1387 VESGLEVAAAPSVTPQA---GTALLAPFPTQRVCSNPPCETHETGTTHTA---TTVTSNM 1440 + A PS TP+ T L T R + + GT HT TT T+ Sbjct: 3840 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 3899 Query: 1441 SSNQDP-------PPAASDQGEVESTQGDSVNITS-------SSAITTTVSSTLTRAVTT 1486 ++ PP +T+G +V +S ++ +TTT ++ T ++ T Sbjct: 3900 TATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT 3959 Query: 1487 VTQSTPVPGPSVPPPEELQVSPGPRQQLPP------RQLLQSASTALMGESAEVLSASQT 1540 + ST G + PP + + LPP R SA++ ++G + ++ T Sbjct: 3960 PSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVT 4019 Query: 1541 PELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP--PTQSEVDQLSLPQELMAEAQAG 1598 PAA +ST + S+ S+ T P P T S ++ Sbjct: 4020 SHTPAAT--TSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 4077 Query: 1599 TTTLMVTGLTPEELAVTAAAEAAAQAAATE 1628 T+TL+ + T + Q A +E Sbjct: 4078 TSTLLPSSPTSAPITTVVTTGCEPQCAWSE 4107 Score = 128 bits (322), Expect = 5e-29 Identities = 296/1306 (22%), Positives = 433/1306 (33%), Gaps = 290/1306 (22%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 P ++ T P+P + P + + A A + T TLLP + + P TT + Sbjct: 2893 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS---TLLPSSPTSAPITTVVT 2949 Query: 463 V-----------------LPTVPGSSISVPTAARTQGVPAVLKVTG----PQATTGTPL- 500 + +P G + R G + G QA G PL Sbjct: 2950 MGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLR 3009 Query: 501 -------------VTMRPASQAGKAPVTVT--------------SLPAGVRMVVPTQS-- 531 + R Q GK + S PA +P+ + Sbjct: 3010 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPG 3069 Query: 532 -----AQGTVIGSSPQMSGMAALAAAAAATQKI--PPSSAPTVLSVPAGTTIVKTMAVTP 584 + T ++ + +G A ++ T I PS+ TV +VP G+T T + T Sbjct: 3070 TTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV-TVPTGSTA--TASSTQ 3126 Query: 585 GTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVA 644 T P A++P + S+ AT A ++ S T T T S ++ Sbjct: 3127 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 3186 Query: 645 QQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG 704 TT T T P S P V T V T+ T +TG Sbjct: 3187 WTRLSQTTTPTATMSTAT----PSSTP-------------ETVHTSTVLTTTATTTGATG 3229 Query: 705 PVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPG 764 V T G A T L T+ TT T T +S GT T+ S + + T G Sbjct: 3230 SVATPSSTPGT--AHTTKVLTTT-----TTGFTATPSSSPGTARTLPVWISTTTTPTTRG 3282 Query: 765 TTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATG 824 +T +IP G T +P T++TT T TG+ A ++ T Sbjct: 3283 STVTPSSIP-----------GTTHTP------TVLTTTTTTVATGSMATPSSSTQTSGTT 3325 Query: 825 HGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLV--VKGTTGVTT 882 H P P T T R ++P + V+ A T+ GTT +T Sbjct: 3326 H------------TPPVPNTTATTHG----RSLSPSSPHTVRTAWTSATSGTLGTTHITE 3369 Query: 883 LGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG 942 T T + G HST A L++P + T + S T + ++TT TA Sbjct: 3370 PSTGTSHTPAATTGTTQHSTPA-LSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATP 3428 Query: 943 GLTTPTITM--QPVSQP--TQVTL-----------------ITAPSGVEAQPVHDLPVSI 981 T + + P S P T VT+ + PSG + ++ + Sbjct: 3429 SKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA- 3487 Query: 982 LASPTTEQPTAT---------VTIADSGQGDVQPGTVTLVCSNPP-------CETHETGT 1025 EQP V + + GQ LVC N C +E Sbjct: 3488 -GGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRV 3546 Query: 1026 --------TNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSN 1077 +T T+ A P T ++ Q AA+ +T S + Sbjct: 3547 FCCNYGHCPSTPATSSTATPSSTPGTT---WILTEQTTAATTTATTGSTAIPSSTPGTAP 3603 Query: 1078 PPCETHETGTTNTATTA-----------------TSNMAGQHGCSNPPCETHETGTTNT- 1119 PP T TT TAT++ TS S P + GTT T Sbjct: 3604 PPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTL 3663 Query: 1120 ---ATTAMSSVGANHQRDARRACAAGTPAVIRIS-VATGALEAAQGSKSQCQTRQTSATS 1175 TT M+++ H + TP S V T + + S T T+ Sbjct: 3664 PEQTTTPMATMSTIHP--------SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3715 Query: 1176 TTMTVMATGAPCSA--GPLLGPS-------MAREPGGRSPAFVQLAPLS--SKVRLSSPS 1224 +T + T A +A GP PS + EP + V + S R ++ + Sbjct: 3716 WILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGT 3775 Query: 1225 IKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTV----------TA 1274 +K L + + V ++ T SS G P S +T+VT T Sbjct: 3776 LKVLTSTATTPTVISSRATPSS-SPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTR 3834 Query: 1275 LEALLCPSATVTQVCSNPPCETHETGT--TNTATTSNAGSAQRVCSNPPCETHETGTTHT 1332 L P+AT++ + ET T T T T TT+ A + S+ P H T T Sbjct: 3835 LSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTT 3894 Query: 1333 ATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDA---TSSHRTVES 1389 TT + + P PP T TT T S+ A T++ TV + Sbjct: 3895 TTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVAT 3954 Query: 1390 GLEVAAAPSVTPQAGTALLAPFP----TQRVCSNPPCETHET------------GTTH-- 1431 G +A S T +GT P P T S PP H GTTH Sbjct: 3955 G-SMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHIT 4013 Query: 1432 ----------TATTVT-------------SNMSSNQDPPPAASDQGEVESTQGDSVNITS 1468 ATT T S+ ++ P P + G T + T Sbjct: 4014 EPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATP 4073 Query: 1469 SSAITTTV------SSTLTRAVTT-----------VTQSTPVPGPS 1497 S T+T+ S+ +T VTT + S P+PGPS Sbjct: 4074 SKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS 4119 Score = 121 bits (304), Expect = 6e-27 Identities = 254/1110 (22%), Positives = 391/1110 (35%), Gaps = 117/1110 (10%) Query: 561 PSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTS 620 PS+ T + +T T +T TTT T S+ S P T + T + T Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 4259 Query: 621 V----SSATNTSTRPII-TVHKSGTVTVAQQAQVVTTVVG--GVTKTITLVKSPISVPGG 673 S+AT +ST+ T H S T T T G + ++S + P Sbjct: 4260 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTA 4319 Query: 674 SALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPT 733 ++ + + T+ QT+ T ST + +T T T A G Sbjct: 4320 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVA 4379 Query: 734 TIITTTQASGAGTKPTILGISSVSPSTTKPGTT-TIIKTIPMSAIITQAGATGVTSS-PG 791 T +T + PT ++ PGT T I + T +G+T SS PG Sbjct: 4380 TPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 4439 Query: 792 IKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 T++TT T TG+ A ++ T H P P T T Sbjct: 4440 TTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTH------------TPPVPNTTATTHG- 4486 Query: 852 GGVRLVTPVTVSAVKPAVTTLV--VKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATP 909 R ++P + V+ A T+ GTT +T T T + G HST A L++P Sbjct: 4487 ---RSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPA-LSSP 4542 Query: 910 ITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITA-PSG 968 + T + S T + ++TT TA T T T+ P S PT + T +G Sbjct: 4543 HPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTR-TSTLLP-SSPTSAPITTVVTTG 4600 Query: 969 VEAQPVHD--LPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVC---SNPPCETHET 1023 E Q L S + T + + G V + L C + P E Sbjct: 4601 CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGEL 4660 Query: 1024 GTTNTATTTVVANLGGHPQPTQVQ---------FVCDRQEAAASLVTSTVGQQNGSVVRV 1074 G + Q + + F C+ ++ TS+ + + Sbjct: 4661 GQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTT 4720 Query: 1075 CSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRD 1134 T T T +T +TAT + G + PP TT TAT++ ++ ++ + Sbjct: 4721 WILTELTTTATTTASTGSTATPSSTP--GTAPPPKVLTSPATTPTATSSKATSSSSPRT- 4777 Query: 1135 ARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQT--SATSTTMTVMATGAPCSAGPL 1192 A P + + + A S T T T+T + M+T P S Sbjct: 4778 -----ATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPET 4832 Query: 1193 LGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEP 1252 S + A A S+ S+P + + A +TAA ++ + P Sbjct: 4833 THTSTVLT----TKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 4888 Query: 1253 RMAPVCESLQGGSPSTTVTVTALE-ALLCPSAT--VTQVCSNPPCETHETGTTNTATTSN 1309 + L +TT T TA + PS+T T + + P T T T T +T+ Sbjct: 4889 GTTWILTEL-----TTTATTTASTGSTATPSSTPGTTWILTEP--STTATVTVPTGSTAT 4941 Query: 1310 AGSAQRVCSNPPCETHETGTTHTATTAT--SNGGTGQPEGGQQPPAGRPCETHQT----T 1363 A S Q P T T T T++ AT S+ GT + A P T T + Sbjct: 4942 ASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSS 5001 Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQA---GTALLAPFPTQRVCSNP 1420 S GTT + P AT S A PS TP+ T L A T + Sbjct: 5002 SLGTTWTRLSQTTTPTATMS----------TATPSSTPETVHTSTVLTATATTTGATGSV 5051 Query: 1421 PCETHETGTTHTA---TTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVS 1477 + GT HT TT T+ ++ P + + I +SS TT + Sbjct: 5052 ATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHT 5111 Query: 1478 STLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSA 1537 ST+ T+T++T + P L + ++ + +TA G +A + S Sbjct: 5112 STVLTTTATMTRAT---NSTATPSSTLGTT-----RILTELTTTATTTAATGSTATLSST 5163 Query: 1538 SQTPEL--------PAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLS--- 1586 T + V ST SS +A + V T + P T S V S Sbjct: 5164 PGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVG 5223 Query: 1587 -------LPQELMAEAQAGTTTLMVTGLTP 1609 LP L + + ++ ++T L P Sbjct: 5224 TTRTPAVLPSSLPTFSVSTVSSSVLTTLRP 5253 Score = 117 bits (294), Expect = 9e-26 Identities = 367/1692 (21%), Positives = 552/1692 (32%), Gaps = 339/1692 (20%) Query: 325 HCAVAINTRLYIWSGRDGYRKAWNNQV---CCKDLWYLETEKPPPPARVQLVRANTNSLE 381 HC V W ++ +N ++ CC D PPP +L A T + + Sbjct: 2260 HCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPT-TELETATTTTTQ 2318 Query: 382 V-------------------SWGAVATADSYLLQLQKYDIPATAATA--TSPTPNPVPSV 420 S AV T L + TA T T+P + P+V Sbjct: 2319 ALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTV 2378 Query: 421 PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAP--APPTTTTIQVLPTVPGSSISVPTAA 478 P + +A P +G T P P AP T T + PT S+ S Sbjct: 2379 PGVATSTLPTRSALPGTTG--SLG-TWRPSQPPTLAPTTMATSRARPTGTASTASKEPLT 2435 Query: 479 RTQGVPAVLKVTGPQATTGTPLV--TMRPASQAGKAPVTVTSLPA-----GVRMVVPTQS 531 + +++ QA T TP TM P + + T P + PT Sbjct: 2436 TSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSG 2495 Query: 532 AQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTT--- 588 G + + + A + + + P V G + T ++ G T Sbjct: 2496 VAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVL--TCSLETGLTCKNE 2553 Query: 589 ------------------------LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSA 624 P+T +S+ S P T + T T+ +S Sbjct: 2554 DQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTAST 2613 Query: 625 TNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKS-PISVPGGSALISNLGKV 683 +T+T + T+ A +V+TT T T+T K+ P S PG + + L Sbjct: 2614 GSTAT-------PTSTLRTAPPPKVLTTTA--TTPTVTSSKATPSSSPGTATALPALRST 2664 Query: 684 ----------------MSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTS 727 + T+ QT+ T ST + +T T T Sbjct: 2665 ATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTG 2724 Query: 728 ADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTT-TIIKTIPMSAIITQAGATGV 786 A G T +T + PT + ++ PGT T I + T G+T Sbjct: 2725 ATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVT 2784 Query: 787 TSS-PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTI 845 SS PG T++TT T TG+ A ++ T H P P T+ Sbjct: 2785 PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTH------------TPPVPNTM 2832 Query: 846 LRTVPMGGVRLVTPVTVSAVKPAVT--TLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTS 903 T R + P + V+ A T T + GTT +T TVT + G HST Sbjct: 2833 ATT----HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTP 2888 Query: 904 ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLI 963 A L++P + T + S T + ++TT TA T T T+ P S PT + Sbjct: 2889 A-LSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPS-KTRTSTLLP-SSPTSAPIT 2945 Query: 964 TAPS-GVEAQPVHD--LPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVC---SNPP 1017 T + G E Q L S + T + + G V + L C + P Sbjct: 2946 TVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPG 3005 Query: 1018 CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSN 1077 E G + VC +E N + C N Sbjct: 3006 VPLRELGQVVECS-------------LDFGLVCRNREQVGKFKMCF----NYEIRVFCCN 3048 Query: 1078 PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137 H T T++TA + S P T T TATT S+ A Sbjct: 3049 ---YGHCPSTPATSSTAMPS-------STPGTTWILTELTTTATTTESTGST-----ATP 3093 Query: 1138 ACAAGTPAVI-------RISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAG 1190 + GT ++ ++V TG+ A +++ T S T+TT TV ++ A Sbjct: 3094 SSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSS----KAT 3149 Query: 1191 PLLGPSMARE-PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGA 1249 P P A P RS A ++P+ A S A+ SS+G Sbjct: 3150 PFSSPGTATALPALRSTA-------------TTPT-----------ATSFTAIPSSSLGT 3185 Query: 1250 GEPRMAPV---CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTA- 1305 R++ ++ +PS+T +L +AT T + + GT +T Sbjct: 3186 TWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTK 3245 Query: 1306 --TTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH-QT 1362 TT+ G S+P GT T S T G P+ P TH T Sbjct: 3246 VLTTTTTGFTATPSSSP-------GTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPT 3298 Query: 1363 TSTGTTMSVSVGALLPDATSSHRTVESG-LEVAAAPSVTPQAGTALLAPFPTQRV----- 1416 T TT +V+ G++ AT S T SG P+ T L+P V Sbjct: 3299 VLTTTTTTVATGSM---ATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWT 3355 Query: 1417 --CSNPPCETH----ETGTTHT--ATTVT-------------SNMSSNQDPPPAASDQGE 1455 S TH TGT+HT ATT T S+ ++ P P + G Sbjct: 3356 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 3415 Query: 1456 VESTQGDSVNITSSSAITTTV--SSTLTRAVTTVT---------------QSTPVPGPS- 1497 +T + T S T+T+ SS + +TTV S P+PGPS Sbjct: 3416 TRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSG 3475 Query: 1498 ----------------VPPPEELQVSPGPRQQLPPRQLLQSASTAL-----------MGE 1530 P L+ + +P R+L Q +L +G+ Sbjct: 3476 GDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGK 3535 Query: 1531 --------------------SAEVLSASQTP------------ELPAAVDLSSTGE---P 1555 S S++ TP + AA ++TG P Sbjct: 3536 FKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIP 3595 Query: 1556 SSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE------LMAEAQAGTT--------- 1600 SS +A V T P T S+ S P+ L + A T Sbjct: 3596 SSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSF 3655 Query: 1601 TLMVTGLTPEELAVTAAAEAAAQAAATEE----AQALAIQAVLQAAQQAVMGTGEPMDTS 1656 TL TG PE+ A + ++T E + L +A A ++ T+ Sbjct: 3656 TLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3715 Query: 1657 EAAATVTQAELGHLSAEGQEGQATTIP---IVLTQQELAALVQQQQLQEAQAQQQHHHLP 1713 +T A +A G ++ P +LT+ A V A A Sbjct: 3716 WILTELTTAAT-TTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAG 3774 Query: 1714 TEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASPA 1773 T + + + I S + P T LP+ + + P+ T V P A Sbjct: 3775 TLKVLTSTATTPTVISSRA---TPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTA 3831 Query: 1774 KLQAAATLTEVA 1785 + + T T A Sbjct: 3832 WTRLSQTTTPTA 3843 Score = 109 bits (273), Expect = 2e-23 Identities = 174/766 (22%), Positives = 269/766 (35%), Gaps = 120/766 (15%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 P ++ T P+P + P + + A A + T TLLP + + P TT + Sbjct: 4542 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS---TLLPSSPTSAPITTVVT 4598 Query: 463 V-----------------LPTVPGSSISVPTAARTQGVPAVLKVTG----PQATTGTPL- 500 +P G + R G + G QA G PL Sbjct: 4599 TGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLG 4658 Query: 501 -------------VTMRPASQAGKAPVTVT--------------SLPAGVRMVVPTQSAQ 533 + R Q GK + S PA +P+ + Sbjct: 4659 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPG 4718 Query: 534 GTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT--VLSVPAGTTIVKTMAVTPGTTTLPA 591 T I + + + + AT P +AP VL+ PA T + T ++ A Sbjct: 4719 TTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTA 4778 Query: 592 TVKVASSPVMVSNPATRMLKTAAAQVGTS--VSSATNTSTRPIITVHKSGTVTVAQQAQV 649 T + + AT + ++ +GT+ + T T + T+H S T + V Sbjct: 4779 TTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTV 4838 Query: 650 VTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI 709 +TT T+ + +P S PG + +++ L T+A T A+TGP Sbjct: 4839 LTTKAT-TTRATSSTSTPSSTPGTTWILTEL-------------TTAATTTAATGPTATP 4884 Query: 710 IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTT----KPGT 765 T G T L TT TTT ++G+ P S +P TT +P T Sbjct: 4885 SSTPGTTWILTEL----------TTTATTTASTGSTATP------SSTPGTTWILTEPST 4928 Query: 766 TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAK---IITAVPKIA 822 T + T+P + T + +P + T TT +TS P+ TA+P + Sbjct: 4929 TATV-TVPTGSTATASSTQATAGTPHVS---TTATTPTVTSSKATPSSSPGTATALPAL- 4983 Query: 823 TGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPV-TVSAVKPAVTTLVVKGTTGVT 881 + T P + L T + TP T+S P+ T V +T +T Sbjct: 4984 ----RSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 5039 Query: 882 TLGTVTGTVSTSLAGAGGHSTSASLATPITTL-GTIATLSSQ----VINPTAITVSAAQT 936 T TG + + T+ + P TT G AT SS + PT +S T Sbjct: 5040 ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMST 5099 Query: 937 TLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTI 996 T++ TT T T+ T +T + A P L + + + T T T Sbjct: 5100 IHTSSTPETTHTSTVL-----TTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAAT 5154 Query: 997 ADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAA 1056 + PGT ++ T T +TAT + + LG P V + A Sbjct: 5155 GSTATLSSTPGTTWILTEPSTIATVMVPTGSTATAS--STLGTAHTPKVVTTMATMPTAT 5212 Query: 1057 ASLV--TSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAG 1100 AS V +STVG V S P T T +++ T G Sbjct: 5213 ASTVPSSSTVGTTRTPAVLPSSLP---TFSVSTVSSSVLTTLRPTG 5255 Score = 106 bits (265), Expect = 2e-22 Identities = 169/665 (25%), Positives = 243/665 (36%), Gaps = 106/665 (15%) Query: 590 PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQV 649 P+T +S+ + S P T + T T+ +S +T+T S T A +V Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTAT-------PSSTPGTAPPPKV 4754 Query: 650 VTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI 709 +T SP + P ++ + T PV TS T +T VT I Sbjct: 4755 LT--------------SPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATS-VTPI 4799 Query: 710 ----IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP--TILGISSVSPSTTKP 763 + T G LP T + T + P++ TT S T T SS S ++ P Sbjct: 4800 PSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTP 4859 Query: 764 GTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIAT 823 GTT I+ + +A T ATG T++P T I T++ T+ T + TA P Sbjct: 4860 GTTWILTELTTAA--TTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS--- 4914 Query: 824 GHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883 G T ++ + P T+ TVP G + +A P V+T T Sbjct: 4915 --STPGTTWILTE--PSTTATV--TVPTGSTATASSTQATAGTPHVST--------TATT 4960 Query: 884 GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGG 943 TVT + +T S+S AT + L + AT + + TAI S+ TT T Sbjct: 4961 PTVTSSKATP-------SSSPGTATALPALRSTAT-TPTATSFTAIPSSSLGTTWTRLSQ 5012 Query: 944 LTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGD 1003 TTPT TM TA + VH V + A+ TT T +V S Sbjct: 5013 TTTPTATMS-----------TATPSSTPETVHTSTV-LTATATTTGATGSVATPSS---- 5056 Query: 1004 VQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063 PGT H T T TT A P A +T Sbjct: 5057 -TPGT-----------AHTTKVPTTTTTGFTATPSSSP-------------GTALTPPTT 5091 Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 S + S P ET T+T T T+ M + P T T T T Sbjct: 5092 TPMSTMSTIHTSSTP-----ETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTT 5146 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQC-QTRQTSATSTTMTVMA 1182 ++ A A + GT ++ + GS + T T+ T +T MA Sbjct: 5147 TATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMA 5206 Query: 1183 TGAPCSAGPLLGPSMAREPGGRSPAFVQLA-PLSSKVRLSSPSIKDL-PAGRHSHAVSTA 1240 T +A + PS + R+PA + + P S +SS + L P G S ST Sbjct: 5207 TMPTATASTV--PSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTP 5264 Query: 1241 AMTRS 1245 R+ Sbjct: 5265 CFCRA 5269 Score = 97.4 bits (241), Expect = 1e-19 Identities = 139/580 (23%), Positives = 211/580 (36%), Gaps = 63/580 (10%) Query: 366 PPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPAN-- 423 PP +V A T + S +++ L AT +TATS TP P ++ Sbjct: 4750 PPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809 Query: 424 -PPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQG 482 P ++ P A + P + P TT T VL T ++ + + + Sbjct: 4810 LPEQTTTPVATMSTIHP------------SSTPETTHTSTVLTTKATTTRATSSTSTPSS 4857 Query: 483 VPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQ 542 P + T T P + P T L T S T SS Sbjct: 4858 TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTP 4917 Query: 543 MSGMAALAAAAAATQKIPPSSAPTVLS--VPAGTTIVKTMAVTPGTTTLPATVKVASSP- 599 + + AT +P S T S AGT V T A TP T+ AT +SSP Sbjct: 4918 GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT--PSSSPG 4975 Query: 600 VMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTK 659 + PA R TA TS ++ ++S T T A + + Sbjct: 4976 TATALPALR--STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVH 5033 Query: 660 TITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTG---QASTGPVTQIIQTKGPL 716 T T++ + + G + ++ T V T+ TG S+ P T + Sbjct: 5034 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPT-TT 5092 Query: 717 PAGTILKLVTSADGKPT---TIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIP 773 P T+ + TS+ + T T++TTT T S+ +PS+T GTT I+ + Sbjct: 5093 PMSTMSTIHTSSTPETTHTSTVLTTTATMTRATN------STATPSSTL-GTTRILTELT 5145 Query: 774 MSAIITQA-GATG-VTSSPG----IKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQ 827 +A T A G+T ++S+PG + P TI T V T T TA + T H Sbjct: 5146 TTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTA------TASSTLGTAHTP 5199 Query: 828 QGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVT 887 + VT + P TVP + S V T V+ + ++ TV+ Sbjct: 5200 KVVTTMAT-----MPTATASTVP----------SSSTVGTTRTPAVLPSSLPTFSVSTVS 5244 Query: 888 GTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPT 927 +V T+L G S+ S G + + N T Sbjct: 5245 SSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKT 5284 Score = 49.7 bits (117), Expect = 3e-05 Identities = 55/248 (22%), Positives = 90/248 (36%), Gaps = 26/248 (10%) Query: 365 PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANP 424 P V T + + G+VAT S +P T T + TP+ Sbjct: 5029 PETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPS--------- 5079 Query: 425 PKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP 484 SP A P P++ + T+T + T+ ++ S T + T G Sbjct: 5080 -SSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTT 5138 Query: 485 AVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMS 544 +L T L T + A + T++S P G ++ S TV+ + Sbjct: 5139 RIL----------TELTTTATTTAATGSTATLSSTP-GTTWILTEPSTIATVM----VPT 5183 Query: 545 GMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSN 604 G A A++ T P T+ ++P T + T GTT PA + + VS Sbjct: 5184 GSTATASSTLGTAH-TPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVST 5242 Query: 605 PATRMLKT 612 ++ +L T Sbjct: 5243 VSSSVLTT 5250 >gi|167736355 mucin 4 isoform a [Homo sapiens] Length = 5284 Score = 140 bits (354), Expect = 1e-32 Identities = 342/1503 (22%), Positives = 524/1503 (34%), Gaps = 194/1503 (12%) Query: 404 ATAATATSPTPNPVPSV-----------PANPPKSPAPAAAAPAVQPLTQVGITLLPQAA 452 A++A+ TP PV S+ P P S + A P + +T A Sbjct: 1158 ASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLL--VTDTSSASTGHAT 1215 Query: 453 PAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTP---LVTMRPASQA 509 P P T + +++P+AA T + A+TG LVT + Sbjct: 1216 PLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVST 1275 Query: 510 GKA---PVTVTSLPAGVRMVVPTQ--SAQGTVIGSSPQMSGMAALAAAAAATQKIP---P 561 G PVT TS A V P S G + + + +A+ T +P P Sbjct: 1276 GDTTPLPVTSTS-SASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSP 1334 Query: 562 SSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSV 621 SSA T + P T +V+ G TT P+ V++ ++ A TS+ Sbjct: 1335 SSASTGDTTPLPVT--DASSVSTGHTT----------PLHVTDASSASTGQATPLPVTSL 1382 Query: 622 SSATNTSTRPIITVHKSGTVTVAQQAQVVTTV----VGGVTKTITLVKSPISVPGGSALI 677 SS + T P+ S T +VT G T S +S ++L Sbjct: 1383 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLP 1442 Query: 678 SNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT 737 + S T P+ + T ASTG T ++ T V++ D P + + Sbjct: 1443 VTIPSAASTGHTTPLPVTD-TSSASTGQATSLLVTD--------TSSVSTGDTTPLPVTS 1493 Query: 738 TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSP-----GI 792 T+ AS P + SPS+ G T + +S+ T +SP G Sbjct: 1494 TSSASTGHVTP----LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGD 1549 Query: 793 KSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMG 852 +P+ + +++G P + T+ +TGH + G T P+ Sbjct: 1550 TTPLPVTDASSVSTGHTTPLPV-TSPSSASTGHTTPLPVTDTSSASKGD------TTPL- 1601 Query: 853 GVRLVTPVTV--SAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPI 910 PVT SA T L V T+ +T T V+ + + + GH+T + +P Sbjct: 1602 ------PVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPS 1655 Query: 911 TTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVE 970 + AT +A T A +T TT T PV+ +++ S + Sbjct: 1656 SASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTD------VSSASTGQ 1709 Query: 971 AQPVHDLPVSILASPTTEQ--PTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNT 1028 A P LPV+ L+S +T P + + + G P VT S + T+T Sbjct: 1710 ATP---LPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDT 1766 Query: 1029 ATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTT 1088 ++ V+ P P + VT G + + P TT Sbjct: 1767 SS---VSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTT 1823 Query: 1089 NTATTATSNMAGQHGCSNP---PCETHETGTTNTATTAMSSVGANHQRD--ARRACAAGT 1143 T S+ + S P P TT+ T SSV H A + T Sbjct: 1824 PLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVST 1883 Query: 1144 PAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGG 1203 + V T A+ G + S+ ST AT P + S++ G Sbjct: 1884 GDTTPLPV-TDTNSASTGDTTPLHVTDASSVSTGH---ATSLPVT-------SLSSASTG 1932 Query: 1204 RSPAFVQLAPLSSKVRLSSP-SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCE-SL 1261 + +P S+ ++P + D + HA S SSV G PV + S Sbjct: 1933 DTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASS 1992 Query: 1262 QGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQR----VC 1317 +T + VT ++ AT V S T +T TS+A + Q V Sbjct: 1993 VSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVT 2052 Query: 1318 SNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGAL 1376 S T +T T T+ S+ TG A H T+ T SVS G Sbjct: 2053 SLSSVSTGDT--TPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTG-- 2108 Query: 1377 LPDATSSHRTVESGL---EVAAAPSVTPQ-AGTALLAPFP--------TQRVCSNPPCET 1424 AT+ H T S L + P +P A T P P T S P +T Sbjct: 2109 --HATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDT 2166 Query: 1425 HETGTTHTAT---TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLT 1481 T H + T TS+ S+ P +D + Q + +TS S+ +T + L Sbjct: 2167 SSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLL 2226 Query: 1482 RAVTTVT---QSTPVP---------GPSVPPP--EELQVSPGPRQQLPPRQL-------- 1519 T+ Q+TP+P G + P P + VS G LP L Sbjct: 2227 VTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDT 2286 Query: 1520 ----LQSASTALMGESA-----EVLSASQ---TPELPAAVDLSSTGEPSS---GQESAGS 1564 + S S+A G + + SAS TP ++ +STG+ + S+ S Sbjct: 2287 TPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSAS 2346 Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG-TTTLMVTGLTPEELAVTAAAEAA-A 1622 AT + + S D LP + A +G TT L VT + T Sbjct: 2347 TGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDT 2406 Query: 1623 QAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT-VTQAELGHLSAEGQEGQATT 1681 +A+T A L + + A+ TG DT+ T V+ A GH AT Sbjct: 2407 SSASTGHATHLPVTGLSSAS------TG---DTTRLPVTNVSSASTGH---------ATP 2448 Query: 1682 IPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVP 1741 +P+ T + + H P L D+ + ++ L + + Sbjct: 2449 LPVTSTSSASTGDTTPLPGTDTSSVSTGHTTP---LLVTDASSVSTGDTTRLPVTSPSSA 2505 Query: 1742 STVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPP 1801 ST P T++ + S P PV AS + A +L + S G LP Sbjct: 2506 STGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTD 2565 Query: 1802 SKA 1804 + A Sbjct: 2566 TSA 2568 Score = 137 bits (345), Expect = 1e-31 Identities = 344/1546 (22%), Positives = 543/1546 (35%), Gaps = 173/1546 (11%) Query: 375 ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPA--A 432 A+ L V+ + A+ D +L D+ + + P P PS + +P P A Sbjct: 1772 AHATPLPVTGLSSASTDD-TTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDA 1830 Query: 433 AAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP 492 ++ + T + +T+ P +A + TT+ LP SS+S A A TG Sbjct: 1831 SSASTGDTTSLPVTI-PSSASSGHTTS----LPVTDASSVSTGHATSLLVTDASSVSTGD 1885 Query: 493 QATTGTPLVTMRPASQAGKAPVTVT---SLPAGVRMVVPTQSAQGTVIGSSPQMSGMAAL 549 TT P+ AS P+ VT S+ G +P S G + + + Sbjct: 1886 --TTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPS 1943 Query: 550 AAAAAATQKIP---PSSAPT--VLSVPA-GTTIVKTMAVTPGTTTLPATVKVA-SSPVMV 602 +A++ T +P SS PT S+P + V T TP T ++V ++P+ V Sbjct: 1944 SASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPV 2003 Query: 603 SNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT 662 ++ ++ A TS+SSA+ T P+ V + + + Q + T + V+ T Sbjct: 2004 TDTSSVSTGQATPLPVTSLSSASTGDTTPL-PVTDTSSASTGQDTPLPVTSLSSVSTGDT 2062 Query: 663 L---VKSPISVPGGSA---LISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL 716 V SP S G A L+++ V + T + T A STG T + T Sbjct: 2063 TPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDA--SSVSTGHATALHVTDA-- 2118 Query: 717 PAGTILKLVTSADGKPTTIITTTQASGAGTKPT-ILGISSVSP--STTKPGTTTIIKTIP 773 +++ D P + + + AS T P + SSVS +T+ P T T Sbjct: 2119 ------SSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDT------ 2166 Query: 774 MSAIITQAGATGVT----SSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQG 829 SA A + VT +S G +P+ + T ++G P + T+ +TGH Sbjct: 2167 SSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPV-TSPSSASTGHAIPL 2225 Query: 830 VTQVVLKGAPGQ----PGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGT 885 + + GQ P T L + G + S+V T + VT+L + Sbjct: 2226 LVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHAT-----SLPVTSLSS 2280 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLT 945 V+ +T L S S ATP+ + + ++S+A T T +T Sbjct: 2281 VSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVT 2340 Query: 946 TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASP----TTEQPTATVTIADSGQ 1001 +P+ + P VT ++ S + P LPV+ +S TT P + A +G Sbjct: 2341 SPSSASTGHATPLHVTDASSVSTGDTTP---LPVTSSSSASSGHTTPLPVTDASSASTGD 2397 Query: 1002 GDVQPGTVTLVCSNPPCETH---------ETG-TTNTATTTVVANLGGHPQPTQVQFVCD 1051 P T T S TH TG TT T V + GH P V Sbjct: 2398 TTPLPVTDTSSASTGHA-THLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLP---VTS 2453 Query: 1052 RQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG-----TTNTATTATSNMAGQHGCSN 1106 A+ T G SV + P T + TT T+ S+ + H Sbjct: 2454 TSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPL 2513 Query: 1107 PPCETHETGTTNTA---TTAMSSVGANH--------QRDARRACAAGTPAVIRISVATG- 1154 P +T T +T T SS+ H A A P + +TG Sbjct: 2514 PVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGH 2573 Query: 1155 ALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPL 1214 A S S T T+ T T A+ + P+ S A G +P V Sbjct: 2574 ATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSA-STGDTTPLPVTDTSS 2632 Query: 1215 SSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCE-SLQGGSPSTTVTVT 1273 +S + + + + HA + SS G PV + S +T++ VT Sbjct: 2633 ASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVT 2692 Query: 1274 ALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTA 1333 ++ AT V + T T T +++ S S P + T H A Sbjct: 2693 DASSVFTGHATSLPVTIPSSASSGHT-TPLPVTDASSVSTGHATSLPVTDASSVSTGH-A 2750 Query: 1334 TTATSNGGTGQPEGGQQPPAGRPCETHQTTSTG--------TTMSVSVGALLPDATSSHR 1385 T + G P P + + STG T S S G P +S Sbjct: 2751 TPLPVTDASSVSTGHATP---LPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLS 2807 Query: 1386 TVESGLEVAAAPSVTPQAGTALLAPFP--------TQRVCSNPPCETHETGTTHTA---T 1434 +V +G + T A T P T P +T T H Sbjct: 2808 SVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPV 2867 Query: 1435 TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSA----------ITTTVSSTLTRA- 1483 T TS+ S +D + + +++TS S+ +T T S++ A Sbjct: 2868 TDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHAN 2927 Query: 1484 ---VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSA---STALMGESAEVLSA 1537 VT+ + ++ +P + S G LP L + +T L S S Sbjct: 2928 PLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSAST 2987 Query: 1538 SQTPELPAAVDLSSTGEPSSGQESA----GSAVVATVVVQPPPPTQ----SEVDQLSLPQ 1589 T LP ++ T S+GQ +A ++ +T P P T S LP Sbjct: 2988 GHTTPLP----VTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPV 3043 Query: 1590 ELMAEAQAG-TTTLMVTGLTPEELA-VTAAAEAAAQAAATEEAQALAIQAV--------- 1638 ++ G TT L VT + T A +A+T +A L + ++ Sbjct: 3044 TSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTT 3103 Query: 1639 -LQAAQQAVMGTGEP-----MDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELA 1692 L + TG DTS A+ T + ++ G T++P+ T Sbjct: 3104 PLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSST 3163 Query: 1693 ALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTAT 1752 + E + H P L D+ + + L+ + + ST P T Sbjct: 3164 GDTTPLLVTETSSVSTGHATP---LLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVT 3220 Query: 1753 ESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLP 1798 ++ + S P PV S A L S G LP Sbjct: 3221 DTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLP 3266 Score = 137 bits (345), Expect = 1e-31 Identities = 307/1269 (24%), Positives = 461/1269 (36%), Gaps = 156/1269 (12%) Query: 383 SWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQ 442 S +V+T D+ L + P++A+T + TP PV S A A A+ P+T Sbjct: 2965 SLSSVSTGDTTPLPVTS---PSSASTGHT-TPLPVTDT------SSASTGQATAL-PVTS 3013 Query: 443 VGITLLPQAAPAPPTTT----TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQ-ATTG 497 P P T T T Q P +P +S+S + T +P VT P A+TG Sbjct: 3014 TSSASTGDTTPLPVTDTSSASTGQATP-LPVTSLSSVSTGDTTPLP----VTSPSSASTG 3068 Query: 498 --TPL-VTMRPASQAGKA-PVTVTSLPA---GVRMVVPTQSAQGTVIGSSPQMSGMAALA 550 TPL VT ++ G+A P+ VTSL + G +P S G + + + Sbjct: 3069 HATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSS 3128 Query: 551 AAAAATQKIP---PSSAPT--VLSVPA-GTTIVKTMAVTPGTTTLPATVKVA-SSPVMVS 603 A+ T +P SSA T S+P T+ T TP T ++V ++P++V+ Sbjct: 3129 ASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVT 3188 Query: 604 NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVT------------VAQQAQVVT 651 + ++ A TS SSA+ T P+ S T A Sbjct: 3189 DASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTR 3248 Query: 652 TVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQ 711 V ++ T +P+ V S++ + G M + T P +SA TG A+ PVT Sbjct: 3249 LPVTDISSASTGQATPLPVTNTSSV--STGDTMPLPVTSP--SSASTGHATPLPVTSTSS 3304 Query: 712 TKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIK- 770 + +SA TT + T S A T T + SPS+ G TT + Sbjct: 3305 ASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTT-PLPVTSPSSASTGHTTPLHV 3363 Query: 771 TIPMSAIITQAGATGVT----SSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHG 826 TIP SA VT +S G +P+ + T +++G P + T++ ++TG Sbjct: 3364 TIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPV-TSLSSVSTGDT 3422 Query: 827 QQGVTQVVLKGAPGQ----PGTILRTVPMGGVRLVTPVTVSAVK-----PAVTTLVVKGT 877 + GQ P T L +V G + S+V P T + Sbjct: 3423 TPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSAS 3482 Query: 878 TGVTTLGTVTGTVSTSLAGA----------------------GGHSTSASLATPITTLGT 915 TG TT VT T S S A S S ATP+ T Sbjct: 3483 TGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDT 3542 Query: 916 IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTL------------- 962 + + S+A T +T P+ + + P VT Sbjct: 3543 SSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLH 3602 Query: 963 ITAPSGVEAQPVHDLPVSILASPTTEQPT-ATVTIADS-GQGDVQPGTVTLVCSNPPCET 1020 +T+PS V LPV+ +S +T T VT A S G P VT S +T Sbjct: 3603 VTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDT 3662 Query: 1021 HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC 1080 T+T++ + P P + VT G + P Sbjct: 3663 TPLPVTDTSSASTGQ---ATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPS 3719 Query: 1081 ETHETGTTNTATTATSNMAGQHGCSNP--PCETHETG-TTNTATTAMSSVGANHQR--DA 1135 T T+ S+ + H P + TG TT T SS H Sbjct: 3720 SVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPV 3779 Query: 1136 RRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATS----TTMTVMATGAPCSAGP 1191 +A T R+ V T A+ G + TS+ S T + V T + + Sbjct: 3780 TDTSSASTDDTTRLPV-TDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHA 3838 Query: 1192 LLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS-----HAVSTAAMTRSS 1246 P +R S P++ +S+ LP S HA + SS Sbjct: 3839 TSLPVTSR--SSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSS 3896 Query: 1247 VGAGEPRMAPVCESLQGGSPSTT-VTVTALEALLCPSATVTQVCSNPPCETHETGTTNTA 1305 G PV + + TT + VT +L AT V S + G T+T Sbjct: 3897 ASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSP---SSASRGDTSTL 3953 Query: 1306 TTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTST 1365 ++A SA + P T + + TT T GQ P P + + ST Sbjct: 3954 PVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPL--PVTSLSSVST 4011 Query: 1366 GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425 G T + V +P + SS T + L V A SV+ GT P P V S T Sbjct: 4012 GDTTPLPV--TIPSSASSGHT--TSLPVTDASSVSTGHGT----PLP---VTSTSSASTG 4060 Query: 1426 ETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTL----T 1481 + TT T TS+ S+ P +D + + +TS S+++T ++ L Sbjct: 4061 D--TTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSA 4118 Query: 1482 RAVTTVTQSTPV----PGPSVPPPEELQVSPGPRQQL-PPRQLLQSASTALMGESAEVLS 1536 + +TV+ +P+ PG + P L+ G R PP Q+ + + + S Sbjct: 4119 TSASTVSSDSPLKMETPGMTTP---SLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRS 4175 Query: 1537 -ASQTPELP 1544 A+ P LP Sbjct: 4176 TAAPIPILP 4184 Score = 136 bits (343), Expect = 2e-31 Identities = 333/1538 (21%), Positives = 516/1538 (33%), Gaps = 204/1538 (13%) Query: 389 TADSYLLQLQKYDIPATAATATSPTPNP---------VPSVPANPPKSPAPAAAAPAVQP 439 T LL Y + TATSP+ +P + + P+ + + +P P Sbjct: 573 TTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESP 632 Query: 440 -LTQVGITLLPQAAPAPPTTTTIQVLP-----TVPGSSISV----PTAARTQGVPAVLKV 489 ++Q G T PQ TT ++ + T PGSS + P+ Q P + Sbjct: 633 AVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAA 692 Query: 490 -------TGPQATTGTPLVTMRPASQA-----GKAPVTVTSLPAGVRMVVPTQSAQGTVI 537 TG TT P ++ A + G + T S + + S G Sbjct: 693 TTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPE 752 Query: 538 GSSPQMSGMAALAAAAAATQ----KIPPSSAPTVLSVPA--GTTIVKTMAVTPGTTTLPA 591 G S + AAA T + +S T S PA G+ TP ++ Sbjct: 753 GQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASG 812 Query: 592 TVKVASSPVMVSNPATRMLKTAAAQVGTS------VSSATNTSTRPIITVHKSGTVTVAQ 645 T S + S TR + T+ +S++ + P+ T S V Sbjct: 813 TTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTF 872 Query: 646 QAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGP 705 + G + SP + P +A IS + + ++ T ++ QA Sbjct: 873 HPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQA---- 928 Query: 706 VTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSP------S 759 T T P P +TS P T T SG+G T IS+ +P S Sbjct: 929 -TDTFSTVPPTPPSITSTGLTS----PQTETHTLSPSGSGKTFTTALISNATPLPVTYAS 983 Query: 760 TTKPGTTTIIKTIPMSAIIT-QAGATGVTS----SPGIKSPITIITTKVMTSGTGAPAKI 814 + G TT + S++ T A VTS S G +P+ + T ++G P Sbjct: 984 SASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLP- 1042 Query: 815 ITAVPKIATGHGQQGVTQVVLKGAPGQ----PGTILRTVPMGGVR-LVTPVTVSAVKPAV 869 +T+ +TG + G P T L + G L T SA Sbjct: 1043 VTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHA 1102 Query: 870 TTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPT-A 928 T+L V T+ V+T T V+ + + + GH+TS P+T +++T + ++ T A Sbjct: 1103 TSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATS----LPVTDTSSVSTGHTTPLHVTDA 1158 Query: 929 ITVSAAQTT---LTAAGGLTTPTITMQPVSQPTQVT-------LITAPSGVEAQPVHDLP 978 + S Q T +T+ ++T T PV+ P+ + L+T S LP Sbjct: 1159 SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLP 1218 Query: 979 VSILASPTTEQPTA---------------TVTIADSGQGDVQPGTVTLVCSNPPCETHET 1023 V+ +S +T+ T+ + + D+ T LV T + Sbjct: 1219 VTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGD- 1277 Query: 1024 GTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAAS--LVTSTVGQQNGSVVRVCSNPPCE 1081 TT T+ + GH P V A+ VTS G + + P Sbjct: 1278 -TTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSS 1336 Query: 1082 THETGTTNTATTATSNMAGQH--------------GCSNP----PCETHETG-TTNTATT 1122 TT T S+++ H G + P + TG TT T Sbjct: 1337 ASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVT 1396 Query: 1123 AMSSVGANH--------QRDARRACAAGTPAVIRISVATG-ALEAAQGSKSQCQTRQTSA 1173 + SS H A A P SV+T A S T T+ Sbjct: 1397 SPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTP 1456 Query: 1174 TSTTMTVMA-TGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR 1232 T T A TG S L+ + + G +P V +S ++ + + Sbjct: 1457 LPVTDTSSASTGQATSL--LVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAS 1514 Query: 1233 HSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTT-VTVTALEALLCPSATVTQVCSN 1291 HA + SS G+ PV + TT + VT ++ T V S Sbjct: 1515 TGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSP 1574 Query: 1292 PPCETHETGTTNTATTSNA--GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQ 1349 T T TS+A G + P TT T TS+ TG Sbjct: 1575 SSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTG------ 1628 Query: 1350 QPPAGRPCETHQTTSTGTT--MSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTAL 1407 TT T S+S G P +S + +G + T A T Sbjct: 1629 -----------DTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGH 1677 Query: 1408 LAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNIT 1467 P P + S TT T S+ S+ Q P + V + + +T Sbjct: 1678 ATPLPVTGLSS-----ATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVT 1732 Query: 1468 SSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTAL 1527 S S+ +T +S L VT + ++ +P + VS LP L SAST Sbjct: 1733 SPSSASTGHASPL--LVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTG-LSSAST-- 1787 Query: 1528 MGESAEVLSASQTPELPAA-VDLSSTGE----PSSGQESAGSAVVATVVVQPPPPTQSEV 1582 T LP V +STG+ P + SA + + V + S Sbjct: 1788 ----------DDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPV-TDASSASTG 1836 Query: 1583 DQLSLPQELMAEAQAG-TTTLMVTGLTPEELA-VTAAAEAAAQAAATEEAQALAIQAVLQ 1640 D SLP + + A +G TT+L VT + T+ A + +T + L + Sbjct: 1837 DTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPV----T 1892 Query: 1641 AAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQL 1700 A G P+ ++A++ T G AT++P+ + Sbjct: 1893 DTNSASTGDTTPLHVTDASSVST-------------GHATSLPVTSLSSASTGDTTPLPV 1939 Query: 1701 QEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNT 1760 + H P L D+ + P + L + ST P T++ + S Sbjct: 1940 TSPSSASSGHTTP---LPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTG 1996 Query: 1761 FVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLP 1798 P PV S A L + S G LP Sbjct: 1997 HATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLP 2034 Score = 117 bits (293), Expect = 1e-25 Identities = 316/1463 (21%), Positives = 499/1463 (34%), Gaps = 183/1463 (12%) Query: 445 ITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMR 504 + LLP P T I GS + P + T A L+ A++ T + Sbjct: 19 LCLLPHVVPGTTEDTLIT------GSKTAAPVTS-TGSTTATLEGQSTAASSRTSNQDIS 71 Query: 505 PASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSA 564 +SQ + T T+ A + TQ T+ SSP + + A T P S Sbjct: 72 ASSQNHQTKSTETTSKAQTDTL--TQMMTSTLF-SSPSVHNVMETAPPDEMTTSFPSSVT 128 Query: 565 PTVLSVPAGTTIVKTMAVTPGT-TTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSS 623 T++ KT+ +T T +TL T + +++ S P T + A Q G S ++ Sbjct: 129 NTLMMTS------KTITMTTSTDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTT 182 Query: 624 ATNTS------------TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVP 671 + TS TR T +S T T+ + + V V S P Sbjct: 183 SWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTS-P 241 Query: 672 GGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGK 731 G S+L SV T + + +T STG +P L VTSA Sbjct: 242 SGETATSSL---CSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSA--- 295 Query: 732 PTTIITTTQASGAGTKPTILGISSVSPST--TKPGTTTIIKTIPMSAIITQAGATGVTSS 789 ++T G P +S +T +K T ++T +S I T T VT+S Sbjct: 296 --ALVTFDPE---GQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTS 350 Query: 790 PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTV 849 + SP + ++ T + T+ P + VT V + + T+ T Sbjct: 351 TVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFL--VTSKVFRMPTSRDSTLGNTE 408 Query: 850 PMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTT--------LGTVTGTVSTSLAGAGGH- 900 L T+SA+ V+T+ T + T T + A G Sbjct: 409 ETS---LSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRP 465 Query: 901 ----STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQ 956 S S ++ I TL T S + T S + T+ G T +T P S Sbjct: 466 HERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATR-LVTGNP-ST 523 Query: 957 PTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNP 1016 T T+ PS V A + PTT +T +G G T Sbjct: 524 GTAGTIPRVPSKVSA-------IGEPGEPTTYSSHSTTLPKTTGAGAQTQWT-------- 568 Query: 1017 PCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCS 1076 ETGTT A L P + Q + + A S +S + ++ S + + Sbjct: 569 ----QETGTTGEA-------LLSSPSYSVTQMI----KTATSPSSSPMLDRHTS--QQIT 611 Query: 1077 NPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTN-----TATTAMSSVGANH 1131 P H T + + + S Q G + P T E+ TT T T +++ G++ Sbjct: 612 TAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSF 671 Query: 1132 QRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGP 1191 IS AT A G T A +T + + + GP Sbjct: 672 TASGHSPSEIVPQDAPTISAATTFAPAPTGDG-----HTTQAPTTALQAAPSSHDATLGP 726 Query: 1192 LLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLP----AGRHSH-AVSTAA--MTR 1244 G S+++ V P + + +S S P A H+H A ST A T+ Sbjct: 727 SGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQ 786 Query: 1245 SSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNT 1304 +S A + S + T + + S T+ SNP ++H T +T Sbjct: 787 TSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTE 846 Query: 1305 ATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCET----- 1359 +++A S + GT H + S G + P+ P ET Sbjct: 847 LLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISR 906 Query: 1360 -HQTTSTGTTMSVSVGALLPDATSSHRTV-ESGLEVAAAPSVTPQAGTALLAPFPTQRVC 1417 QT T T+ +L AT + TV + + + +PQ T L+P + + Sbjct: 907 MAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTF 966 Query: 1418 SNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVS 1477 + + T T S+ S+ P +D V + + +TS S+++T + Sbjct: 967 TTALI----SNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHT 1022 Query: 1478 STLTRAVTTVTQS---TPVP---------GPSVPPP--EELQVSPGPRQQLPPRQLLQSA 1523 + L T+ + TP+P G S P P + S G LP L ++ Sbjct: 1023 TPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSAS 1082 Query: 1524 -------------------STALMGESAEVLSASQTPELPAA-VDLSSTGEPSSGQESAG 1563 +T+L +S T LP +STG +S + Sbjct: 1083 TGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDT 1142 Query: 1564 SAV---------------VATVVVQPPPPTQ----SEVDQLSLPQELMAEAQAGTTTLMV 1604 S+V +T P P T S D LP + A G T ++ Sbjct: 1143 SSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLL 1202 Query: 1605 TGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPM-DTSEAAATVT 1663 T A A++ A ++ + +A T P+ DTS A+ Sbjct: 1203 VTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQA 1262 Query: 1664 QAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSL 1723 + L ++ G T +P+ T V + + H P P SL Sbjct: 1263 TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATP----LPVTSL 1318 Query: 1724 NDPAI-ESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLT 1782 + + ++ L + + ST P T++ + S P V AS A A L Sbjct: 1319 SSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLP 1378 Query: 1783 EVANGIESLGVKPDLP-PPPSKA 1804 + S G LP PS A Sbjct: 1379 VTSLSSVSTGDTTPLPVTSPSSA 1401 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 138 bits (347), Expect = 6e-32 Identities = 264/1188 (22%), Positives = 432/1188 (36%), Gaps = 150/1188 (12%) Query: 405 TAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLP--QAAPAPPTTTTIQ 462 T + TS +VP + P P V V T +P +P P TT Sbjct: 10850 TPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSM 10909 Query: 463 VLPTVPGSSISVPTAARTQGVPAVLK--VTGPQATTGT---------------PLVTMRP 505 +S ++PT + GVP V+ VT +A T T P + Sbjct: 10910 ATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSH 10969 Query: 506 ASQAGKA--------PVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQ 557 ++AG A P VTSL A R V T T+ P+ + A + A A+ Sbjct: 10970 GTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASS 11029 Query: 558 KIP------PSSAPTVLSVPAG--TTIVKTMAVTPG---TTTLPATVKVASSPVMVSNPA 606 +P P ++++ +G +T + T+ ++PG TT AT A + V P Sbjct: 11030 TVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPT 11089 Query: 607 TRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKS 666 + + S A ++T PI+T+ S T A T G + L S Sbjct: 11090 VSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMA----TSHGVEASSAVLTVS 11145 Query: 667 PISVPG--------GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI-IQTKGPLP 717 P VPG A+ S +++ +P T+++ + ++ I P Sbjct: 11146 P-EVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTV 11204 Query: 718 AGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI 777 G + LVTS+ + + T AS ++P ++ PGT +P + Sbjct: 11205 QGLVTSLVTSSGSETSAFSNLTVAS---SQP-----ETIDSWVAHPGTEAS-SVVPTLTV 11255 Query: 778 ITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG 837 T T ++ + P +T T+ + +++ T +P T + + + Sbjct: 11256 STGEPFTNISL---VTHPAESSSTLPRTTSRFSHSELDT-MPSTVTSPEAESSSAISTTI 11311 Query: 838 APGQPGTILRTVPMGGVRLVTPVTVSAVKPAV--TTLVVKGTTGVTTLGTVTGTVSTSLA 895 +PG PG + V G +SA P V + + T T VT T Sbjct: 11312 SPGIPGVLTSLVTSSGR------DISATFPTVPESPHESEATASWVTHPAVTSTTVPRTT 11365 Query: 896 GAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG---GLTTPTITMQ 952 HS + + T+ G AT I + + +T++G +T PT+T+ Sbjct: 11366 PNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLS 11425 Query: 953 PVSQPTQVTLITAPSGVEAQPVHDLPVS---------ILASPTTEQPTATVTIADSGQGD 1003 T + IT + + LPVS ++ S T+ T T+ ++ Sbjct: 11426 SGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTET---P 11482 Query: 1004 VQPGTVTLVCSNP-------PCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAA 1056 +P T + +P P T + + + TT VA P+ + Sbjct: 11483 YEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDM 11542 Query: 1057 ASLVTSTV---GQQNGSVVRVCSNPPCETHETGT--TNTATTATSNMAGQHGCSNPPCET 1111 + LVTS V G + S P E T T T+ A T+T+ S+ +T Sbjct: 11543 SDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDT 11602 Query: 1112 HETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQG------SKSQ 1165 + T+ S V P V+ V + A + + S + Sbjct: 11603 APSMVTSPGVDTRSGVPTT-------TIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGE 11655 Query: 1166 CQTRQTSAT----STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLS 1221 +T +SAT T TV P S + + P +P ++ +S S Sbjct: 11656 PETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTP----VSRTTSSFSHS 11711 Query: 1222 SPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTV-TVTALEALLC 1280 SP + A S+A +T S GA E + + S G + STTV T+T + Sbjct: 11712 SPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSS--GAATSTTVPTLTHSPGM-- 11767 Query: 1281 PSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNG 1340 T + ++P ET +T +T + + + P ET T T ++ + Sbjct: 11768 -PETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLL 11826 Query: 1341 GTGQPEGGQQPPAG-------RPCETHQTTSTGT---TMSVSVGAL----LPDATSSHRT 1386 TG P A P TH T T T T ++S+G L L +SS T Sbjct: 11827 VTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAET 11886 Query: 1387 VESGLEVAAAPSVTPQAGTALLAPFPTQRVCS----NPPCETH----ETGTTHTATTVTS 1438 S L + +P+V+ + ++ P Q V S P T E T T TT+T Sbjct: 11887 STSTLTLTVSPAVSGLSSASITTDKP-QTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTL 11945 Query: 1439 NMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTT 1486 S PP + +G +T + + +++ TT S T+ + TT Sbjct: 11946 IPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTT 11993 Score = 123 bits (308), Expect = 2e-27 Identities = 288/1343 (21%), Positives = 503/1343 (37%), Gaps = 167/1343 (12%) Query: 401 DIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTT 460 ++ ++TATS + ++P N S A P V T P +P T T Sbjct: 10621 ELDTVSSTATSHGADVSSAIPTNISPSELDALT-PLVTISGTDTSTTFPTLTKSPHETET 10679 Query: 461 IQVLPTVPGSSIS-----VPTAAR--TQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAP 513 T P + S +P + + P++ G + ++ P++T+ P ++ Sbjct: 10680 RTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAE-DLVT 10738 Query: 514 VTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAG 573 VTS M +PT T+ P+ +A+ + S+ PT PA Sbjct: 10739 SQVTSSGTDRNMTIPTL----TLSPGEPK-----TIASLVTHPEAQTSSAIPTSTISPAV 10789 Query: 574 TTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRM-LKTAAAQVG------TSVSSATN 626 + +V +M + T + +SP PAT + L T AQ TS+ + Sbjct: 10790 SRLVTSMVTSLAAKTSTTNRALTNSP---GEPATTVSLVTHPAQTSPTVPWTTSIFFHSK 10846 Query: 627 TSTRPIITV-HKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISV--------PGGSALI 677 + T P +T H + + + V T V G VT +T ++ IS PG Sbjct: 10847 SDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETT 10906 Query: 678 SNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT 737 ++ + + T V+ G VT ++ T T + ++T + G+P T T Sbjct: 10907 PSMATSHGEEASSAIPTPTVS-PGVPGVVTSLV-TSSRAVTSTTIPILTFSLGEPET--T 10962 Query: 738 TTQASGAGTK-----PTIL----GISSVSPSTTKPGTTTIIKTIPMS--------AIITQ 780 + A+ GT+ PT+L G+ + ++++ T+T + T+ +S ++ T Sbjct: 10963 PSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATS 11022 Query: 781 AGATGVTSSPGIKSPITIITTKVMTSGTGA-----PAKIIT-----AVPKIATGHGQQGV 830 GA ++ P + + + T ++TS +G P I++ P +AT HG + Sbjct: 11023 HGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEAS 11082 Query: 831 TQVVLKG-APGQPGTILRTVPMGGVRLVTPV---TVSAVKPAVTTLVVKGTTGVTTLGTV 886 + V +PG G + V T + T+S+ +P TT + + GV V Sbjct: 11083 SAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPE-TTPSMATSHGVEASSAV 11141 Query: 887 TGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT 946 TVS + G ++S A TT+ T+ T+SS T V+ ++ + +A Sbjct: 11142 L-TVSPEVPGMVTSLVTSSRAVTSTTIPTL-TISSDEPETTTSLVTHSEAKMISA----I 11195 Query: 947 PTITMQPVSQPTQVTLITAPSGVEAQPVHDLPV---------SILASPTTEQPTATVTIA 997 PT+ + P Q +L+T+ SG E +L V S +A P TE + T+ Sbjct: 11196 PTLAVSPTVQGLVTSLVTS-SGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLT 11254 Query: 998 DSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 S +P T + ++P E+ +T TT+ ++ P+ V +A Sbjct: 11255 VSTG---EPFTNISLVTHPA----ESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAI 11307 Query: 1058 S---------LVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPP 1108 S ++TS V + P HE+ T + T + + + P Sbjct: 11308 STTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTSTTVPRTTPN 11367 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAA-GTPAVIRISVATGALEAAQGSKSQCQ 1167 E TT + T S GA D + P ++ V + + + + Sbjct: 11368 YSHSEPDTTPSIAT---SPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTL 11424 Query: 1168 TRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKD 1227 + T+T+ + SA P L S PG + + + P++ + Sbjct: 11425 SSGEPETTTSFITYSETHTSSAIPTLPVS----PGASKMLTSLVISSGTDSTTTFPTLTE 11480 Query: 1228 LPAGRHSHAVSTA--AMTRSSVGAGEPRMA--------PVCESLQGGSPSTTVTVTALE- 1276 P + A+ A T + V P+ + PV + G S+ V+ T + Sbjct: 11481 TPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISP 11540 Query: 1277 -------ALLCPSATVTQVCSNPPCET-HETGTTNTATTSNAGSAQRVCSNPPCETHETG 1328 +L+ S T T ET +E TT T T A ++ V P +H Sbjct: 11541 DMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRG- 11599 Query: 1329 TTHTATTATSNGGTGQPEGGQQ---PPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHR 1385 + TA + ++ G G PP+ T Q TS+ T S ++ L P Sbjct: 11600 -SDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPET 11658 Query: 1386 TVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMS-SNQ 1444 T S A T T + P+ + TH T+ + TS+ S S+ Sbjct: 11659 TASS-----ATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSP 11713 Query: 1445 DPPP--AASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPE 1502 D P A S + E S +++ + +T+ ++S+ TTV T PG P Sbjct: 11714 DATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPG---MPET 11770 Query: 1503 ELQVSPGPRQQLPPR--------QLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGE 1554 +S PR + Q+ ++ ++ + AE +A T + L TG Sbjct: 11771 TALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGT 11830 Query: 1555 PSSGQESAGSAVVA--TVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPE-- 1610 S V+ T + P T++ +P ++ TT L+ T + E Sbjct: 11831 SRVDLSPTASPGVSAKTAPLSTHPGTETST---MIPTSTLSLGLLETTGLLATSSSAETS 11887 Query: 1611 ----ELAVTAAAEAAAQAAATEE 1629 L V+ A + A+ T + Sbjct: 11888 TSTLTLTVSPAVSGLSSASITTD 11910 Score = 120 bits (302), Expect = 1e-26 Identities = 276/1233 (22%), Positives = 461/1233 (37%), Gaps = 248/1233 (20%) Query: 456 PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVT 515 PT TT +V S V ++ RT + GP +T P ++ R ++ +P Sbjct: 6976 PTGTTAEV------SRTEVTSSGRTS-------IPGPSQSTVLPEISTRTMTRLFASPTM 7022 Query: 516 VTSLPAGVRMVVPTQSAQGTVIGSSPQ-------MSGMAALAAAAAATQKIP-------- 560 S M +PTQ+ GS+ Q + + + TQ+ P Sbjct: 7023 TES----AEMTIPTQTGPS---GSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLM 7075 Query: 561 -----------------PSSAPTVLSVPAGTT---IVKTMAVTPGTTTLPATVKVASSPV 600 PSS P++LS+PA T+ I T+ VT ++ LP T + SSPV Sbjct: 7076 SRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPV 7135 Query: 601 MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIIT---------VHKSGTVTVAQQAQVVT 651 T ML T+ V +S ++TS + T VH S T T A ++ + Sbjct: 7136 TT----TDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPS-TNTAASNVEIPS 7190 Query: 652 TVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKP--VQTSAVTGQASTGPVTQI 709 + G + + L S S I++ + +V + P ++TS + ++ + ++ Sbjct: 7191 S--GHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKL 7248 Query: 710 IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAG-TKPTILGISSVSPSTTKPGTTTI 768 +T + + ++ TSA +I TT+ S T + IS + ST P +T Sbjct: 7249 RETGSSVETSSAIE--TSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTT 7306 Query: 769 IKTI--PMSAIITQAGATGV---TSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIAT 823 K I P S I+ ++ + TS PG S T T T ++ + Sbjct: 7307 RKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTF------TLDTSTTPSLVITHSTMTQ 7360 Query: 824 GHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883 +T +V +GA G V + + V P + L + Sbjct: 7361 RLPHSEITTLVSRGA-------------GDVPRPSSLPVEETSPPSSQLSLSAM------ 7401 Query: 884 GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATL-----SSQVINPTAITVSAAQTTL 938 ++ + +S A HS+SAS+ T + T G + T S++ + ++S+ + Sbjct: 7402 --ISPSPVSSTLPASSHSSSASV-TSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEI 7458 Query: 939 TAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIAD 998 A +TT T + P S + T+ SG H+ P S+L T + T+ + Sbjct: 7459 LATSEVTTDTEKIHPFSNTAVTKVGTSSSG------HESPSSVLPDSETTKATSAM---- 7508 Query: 999 SGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDR-QEAAA 1057 GT++++ G T+ +T T + Q + R +E + Sbjct: 7509 --------GTISIM-----------GDTSVSTLTPALSNTRKIQSEPASSLTTRLRETST 7549 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 S TS + N + +V + E T + + T+ S G Sbjct: 7550 SEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMS------------------GPE 7591 Query: 1118 NTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTT 1177 + + S+G + A A + I+ TG E+ S T T + T Sbjct: 7592 QSTMSQDISIGTIPRISASSVLTES--AKMTITTQTGPSESTLESTLNLNTATTPSWVET 7649 Query: 1178 MTVMATGAPCSAGPLLGPSMAREPGG---RSPAFV-QLAPLSSKVRLSSPSIKDLPAGRH 1233 +++ G P P + SM R PGG SP FV + +P SS + LPA Sbjct: 7650 HSIVIQGFP---HPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPL--------SLPAVTS 7698 Query: 1234 SHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTT----------------VTVTALEA 1277 H VST + P PV L G +TT ++ T+ E Sbjct: 7699 PHPVSTTFLAHIP-----PSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHER 7753 Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVC---SNPPCETHETGTTHTAT 1334 L T +P + TG TN ATTS+ +Q S+P C T G T T Sbjct: 7754 LTTYKDTAHTEAVHP---STNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLT 7810 Query: 1335 TATSNGGTGQPE---GGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391 + + T + + P R + TS+GT MS TV S + Sbjct: 7811 STPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMS---------------TVLSKV 7855 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETG--TTHTATTVTSNMSSNQDPPPA 1449 A ++ + T++ P P Q S P T +T T ++ ++ N P Sbjct: 7856 PTGATTEISKEDVTSI--PGPAQSTIS-PDISTRTVSWFSTSPVMTESAEITMNTHTSPL 7912 Query: 1450 ASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPG 1509 + +TQG S TSS+ T ST+++ + ST + P + +SP Sbjct: 7913 GA------TTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLM---RRGPEDVSWMSPP 7963 Query: 1510 PRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVAT 1569 ++ P S +LM A + + LP ++ SS+ P + ++G A Sbjct: 7964 LLEKTRP-------SFSLMSSPATTSPSPVSSTLPESI--SSSPLPVTSLLTSGLAKTTD 8014 Query: 1570 VVVQPPPP-TQSEVDQLSLPQELMAEAQAGTTT 1601 ++ + P T S + S E++A ++ T T Sbjct: 8015 MLHKSSEPVTNSPANLSSTSVEILATSEVTTDT 8047 Score = 119 bits (298), Expect = 3e-26 Identities = 344/1629 (21%), Positives = 570/1629 (34%), Gaps = 284/1629 (17%) Query: 376 NTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAP 435 +T+S+ + + ++LLQ K D ++A T++ P P P P A+P Sbjct: 10177 DTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWP-PASQYTEIPVDIITPFNASP 10235 Query: 436 AVQPLTQVGITLLPQAA-----------------PAPPTTTTIQVLPTVPGSSIS----- 473 ++ T GIT P++ P+ T +T V+P++ + S Sbjct: 10236 SITEST--GITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTG 10293 Query: 474 VPTAARTQGVPAVLKVTGP-QATTGT-----PLVTMRPASQAGKAPVTVTSLPA--GVRM 525 VP A G P +GP AT T P T P S + +++PA + Sbjct: 10294 VPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITS 10353 Query: 526 VVPTQSAQGTVIG--SSPQMSGMAALAAAAAATQKIPPSSAP-------------TVLS- 569 T T +G SS + ++ ++Q SS+P TV S Sbjct: 10354 SSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSA 10413 Query: 570 --VPA-GTTIVKTMAVTPGTTTLP------ATVKVASSPVMVSNPAT-RMLKTAAAQVGT 619 VP+ T + +T + T +P T++ P ++PA+ + L T + Sbjct: 10414 YQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRME 10473 Query: 620 SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--------VGGVTKTITLVKSPISVP 671 + ++A T+T + T ++ T+T + + T+ + T ++ +P P Sbjct: 10474 TTTTALKTTTTALKTTSRA-TLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFP 10532 Query: 672 G----GSALISNLGK---------VMSVVQTKPVQTSAVTGQ--ASTGPVTQIIQTKGPL 716 S+L ++LG SV + T+++ + A PV Q + Sbjct: 10533 DVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSE 10592 Query: 717 PAGTILKLVTSADGKPT--------------TIITTTQASGAGTKPTI------------ 750 P T ++ A+ PT T+ +T + GA I Sbjct: 10593 PDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDAL 10652 Query: 751 ---LGISSVSPSTTKPGTT---------------------TIIKTIPMSAIITQAGATGV 786 + IS STT P T TI +TIP + + Sbjct: 10653 TPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSI 10712 Query: 787 TSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTIL 846 +SPG ++ I +MT GA + + V T + +T L +PG+P TI Sbjct: 10713 ATSPGAETSSAI---PIMTVSPGAEDLVTSQVTSSGT---DRNMTIPTLTLSPGEPKTIA 10766 Query: 847 RTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH-STSAS 905 V + + + S + PAV+ LV T+ VT+L T T + +L + G +T+ S Sbjct: 10767 SLVTHPEAQTSSAIPTSTISPAVSRLV---TSMVTSLAAKTSTTNRALTNSPGEPATTVS 10823 Query: 906 LAT-PITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLIT 964 L T P T T+ +S + + T + T+ A PT T+ T+V + Sbjct: 10824 LVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVS-----TEVPGVV 10878 Query: 965 APSGVEAQPVHDLPVSILA-SPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHET 1023 P ++ V + IL SP + T ++ + + T T+ P T Sbjct: 10879 TPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLV 10938 Query: 1024 GTTNTATTTVVANLG---GHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC 1080 ++ T+T + L G P+ T E A S V + + + G V + ++ Sbjct: 10939 TSSRAVTSTTIPILTFSLGEPETTPSMATSHGTE-AGSAVPTVLPEVPGMVTSLVASSRA 10997 Query: 1081 ETHETGTTNTAT----TATSNMAGQHGC----SNPPCETHETGTTNTATTAMSSVGANH- 1131 T T T T + T +MA HG + P G + T+ S V + Sbjct: 10998 VTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSI 11057 Query: 1132 --------QRDARRACAAGTPAVIRISVATGALE-AAQGSKSQCQTRQTSATSTTMTVMA 1182 + + + A A +V T + G + T + TSTT+ ++ Sbjct: 11058 PTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILT 11117 Query: 1183 TGAPCSAGPLLGPSMAREPG-GRSPAFVQLAP---------LSSKVRLSSPSIKDLPAGR 1232 S+ P PSMA G S A + ++P ++S ++S +I L Sbjct: 11118 LS---SSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISS 11174 Query: 1233 HSHAVSTAAMTRSSVG--------AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSAT 1284 +T+ +T S A P + + SL S S T + L T Sbjct: 11175 DEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPET 11234 Query: 1285 VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQ 1344 + ++P E T T +T +N TH ++ T TS Sbjct: 11235 IDSWVAHPGTEASSVVPTLTVSTGEP------FTNISLVTHPAESSSTLPRTTSR--FSH 11286 Query: 1345 PEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAG 1404 E P E +++ TT+S + +L +S SG +++A P+ Sbjct: 11287 SELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTS-----SGRDISATFPTVPE-- 11339 Query: 1405 TALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMS-SNQDPPPAASDQGEVESTQGDS 1463 +P ++ S TH T+ T T N S S D P+ + E+T D Sbjct: 11340 ----SPHESEATAS---WVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEAT-SDF 11391 Query: 1464 VNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPE------------------ELQ 1505 IT S + V+S +T + T + + P S PE L Sbjct: 11392 PTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLP 11451 Query: 1506 VSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL-------PAAVDLSSTGEPSSG 1558 VSPG + L L+ S+ T + PE PA + Sbjct: 11452 VSPGASKML--TSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKF 11509 Query: 1559 QESAGSAVVATVVVQPPPPTQSEV-------DQLSLPQELMAEAQAGTTTLMVT-GLTPE 1610 S + + P P S V D L L+ + T+T T TP Sbjct: 11510 SHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPY 11569 Query: 1611 ELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHL 1670 E TA +T + + + + M T +DT T T Sbjct: 11570 EPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTT------- 11622 Query: 1671 SAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIES 1730 +IP V+T Q V + A P E A S P ++ Sbjct: 11623 -------IPPSIPGVVTSQ-----VTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQT 11670 Query: 1731 NCLNELAGTVPST--------VALLPSTATESLAPSNTFVAPQ----PVVVASPAKLQAA 1778 + TVPS+ V P T+T +++F PV+ SP ++ Sbjct: 11671 GFTVPIR-TVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASS 11729 Query: 1779 ATLTEVANG 1787 A LT ++ G Sbjct: 11730 AVLTTISPG 11738 Score = 115 bits (287), Expect = 6e-25 Identities = 336/1664 (20%), Positives = 582/1664 (34%), Gaps = 251/1664 (15%) Query: 373 VRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAA 432 V+AN + E A+A +++ Q T T P P S+P + Sbjct: 5128 VKANNSGHESHSPALADSETPKATTQM------VITTTVGDPAPSTSMPVHGSSETTNIK 5181 Query: 433 AAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP 492 P ++ T Q + P T T +L VP +I T + GV + K++ P Sbjct: 5182 REPTYFLTPRLRETSTSQESSFP--TDTSFLLSKVPTGTI---TEVSSTGVNSSSKISTP 5236 Query: 493 QATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI--GSSPQMSGMAALA 550 T + P + G+ P TS + T+SA+ T+ S P+ + + L Sbjct: 5237 DHDKST----VPPDTFTGEIPRVFTSS-------IKTKSAEMTITTQASPPESASHSTLP 5285 Query: 551 AAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTT---TLPATVKVASSPVMVSNPAT 607 + T + + P + + M + PG T P + +S ++S+PA Sbjct: 5286 LDTSTTLSQGGTHSTVTQGFPY-SEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAM 5344 Query: 608 RMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSP 667 T+ + V ++ + +S P+ + S VT TT V G T SP Sbjct: 5345 ----TSPSPVSSTSPQSIPSSPLPVTALPTSVLVT--------TTDVLGTT-------SP 5385 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTS 727 SV +S++ T A ++ VT + T G L S Sbjct: 5386 ESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNV-GTSGSGHKSQSSVLADS 5444 Query: 728 ADGKPTTIITTTQASG----------------------AGTKPTILGISSVSPSTTKPGT 765 K T +++TT G A P + S+ +++ T Sbjct: 5445 ETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTET 5504 Query: 766 TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGH 825 T +P AI TQA T ++SS S + T S TG ++ T+ P + Sbjct: 5505 NTAFSYVPTGAI-TQASRTEISSSRTSISDLDRPTIAPDIS-TGMITRLFTS-PIMTKSA 5561 Query: 826 GQQGVTQVVLKGAPGQ---PGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTT 882 TQ GA Q P T+ GG T TVS P ++ T Sbjct: 5562 EMTVTTQTTTPGATSQGILPWDTSTTLFQGG----THSTVSQGFPHSEITTLRSRTPGDV 5617 Query: 883 LGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG 942 T V + +G S S + +P+++ ++ S + TA+ S TT G Sbjct: 5618 SWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSP-ESIPSSPLPVTALLTSVLVTTTNVLG 5676 Query: 943 GLTTPTITMQP--VSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 + +T P +S PTQ L T + +H AS T A V + SG Sbjct: 5677 TTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMH-------ASMHTNTAVANVGTSISG 5729 Query: 1001 ---QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 Q V + T ++P T G T+ +T+T + + ++ Sbjct: 5730 HESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRT 5789 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117 S +TV + + + V P T E T T++ + ++G P + ET T Sbjct: 5790 SEEINTVTETSTVLSEV---PTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITR 5846 Query: 1118 NTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTR-QTSATST 1176 +T G+ + GT + +++ T + + +G+ S R S +T Sbjct: 5847 --LSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETT 5904 Query: 1177 TMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPS-----IKDLPAG 1231 TM+ G + P + + + PA + L S V SSP+ L +G Sbjct: 5905 TMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSG 5964 Query: 1232 R---------HSHAVSTAAMTRSSVGAGEPRMAPVCESLQG-----GSPSTTVTVTALEA 1277 R HS V+++ + SS +GE + + + + T + T Sbjct: 5965 RRKTIDMLDTHSELVTSSLPSASSF-SGEILTSEASTNTETIHFSENTAETNMGTTNSMH 6023 Query: 1278 LLCPSATVTQVCSN--PPCETHETGTTNTATTSNAGSAQ-----RVCSNPPC-------- 1322 L S ++ S PP T +TS GS + R ++P Sbjct: 6024 KLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDST 6083 Query: 1323 -----ETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALL 1377 T E+ T ++ + + + E P P T S + Sbjct: 6084 ALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDIS--------- 6134 Query: 1378 PDATSSHR-----TVESGLEVAA--APSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430 P+A+SSH T+ + +A PS G L P T + + Sbjct: 6135 PEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDS 6194 Query: 1431 HTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQS 1490 T + + ++++ P ++++ S+Q + TS S +T+T+ T ++ +VT Sbjct: 6195 ETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTS- 6253 Query: 1491 TPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV--- 1547 VP P++ ++ + P + P Q+ L A + + P + AV Sbjct: 6254 --VPTPTLAKITDMDTNLEPVTRSP-----QNLRNTLATSEATTDTHTMHPSINTAVANV 6306 Query: 1548 -------DLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE-LMAEAQAGT 1599 + T P S A SAVV T + + S+P+ M + ++ T Sbjct: 6307 GTTSSPNEFYFTVSPDSDPYKATSAVVITST------SGDSIVSTSMPRSSAMKKIESET 6360 Query: 1600 TTLMVTGL----TPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPM-- 1653 T ++ L T +++ ++ A T ++ + +++ ++ GT +P Sbjct: 6361 TFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMS 6420 Query: 1654 -DTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHL 1712 DTS + T+ G +E + T P T Q L + +QA H Sbjct: 6421 PDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQ--GTLTWDTSITTSQAGT--HSA 6476 Query: 1713 PTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASP 1772 T + D + S ++GT P +V S+++ P+ T +P PV P Sbjct: 6477 MTHGFSQLDL---STLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAIT--SPSPVPTTLP 6531 Query: 1773 AKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQWFDVGVIKGTNVMVTHYFLPP 1832 +P P + P G++K T+++ + LPP Sbjct: 6532 ES-------------------RPSSPVHLTSLPTS--------GLVKTTDMLASVASLPP 6564 Query: 1833 DDAVPSDDDLGTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPG 1892 + S T D +K + P T G + +S + A+ Sbjct: 6565 NLGSTSHKIPTTSEDIKDTEK--MYPSTNIAVTNVGTTTSEKESYSSVPAYS-------- 6614 Query: 1893 APCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQAGG 1936 EPP VTS + +++ I S+ G Sbjct: 6615 ------------------EPPKVTSPMVTSFNIRDTIVSTSMPG 6640 Score = 108 bits (269), Expect = 7e-23 Identities = 307/1464 (20%), Positives = 535/1464 (36%), Gaps = 260/1464 (17%) Query: 427 SPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT---VPGSSISVPTAARTQGV 483 SP A A ++ + +T P P T+T+Q T V +S+ PT A+ + Sbjct: 6211 SPFSAEEANSLSSQAPLLVTTSPS-----PVTSTLQEHSTSSLVSVTSVPTPTLAKITDM 6265 Query: 484 ----------PAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLP------------- 520 P L+ T + T TM P+ A V TS P Sbjct: 6266 DTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDSDP 6325 Query: 521 --AGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAA-----------AATQKIPPSSAPTV 567 A +V+ + S V S P+ S M + + + +QKI SS + Sbjct: 6326 YKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGSSSDTST 6385 Query: 568 LSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRML--------------KTA 613 + A T ++ T T++ +++ P M + +TR + +T Sbjct: 6386 VFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTI 6445 Query: 614 AAQVGTSVSSATNTST-RPIITVHKSGT---VTVAQQAQVVTTVVGGVTKTITLVKSPIS 669 A Q G +++ T T IT ++GT +T ++T+ V + I+ SP S Sbjct: 6446 ATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYIS-GTSPPS 6504 Query: 670 VPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSAD 729 V S+ S+L + ++ PV T+ + S+ + T G + +L V S Sbjct: 6505 VEKTSS-SSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLP 6563 Query: 730 GKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIK---------------TIPM 774 + + K T S + + T GTTT K T PM Sbjct: 6564 PNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPM 6623 Query: 775 SAIITQAGATGVTSSPGIKSPITIITTKVMTS------GTGAPAKIITA------VPKIA 822 TS PG S IT I + S GT I + + K+ Sbjct: 6624 VTSFNIRDTIVSTSMPG-SSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLT 6682 Query: 823 TGHGQQGVTQVVLKGAPGQPGTILRT-VPMGGVRLV--TPVTVSAVKPAVTTLVVK--GT 877 TG + T+V PG T P ++ P+++ + + T++ + Sbjct: 6683 TGATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPP 6742 Query: 878 TGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTT 937 G T+ GT T T+ + AG HS A+ P + + T+ ++++ T I S +T+ Sbjct: 6743 LGSTSQGTFTLDTPTTSSRAGTHS-MATQEFPHSEMTTVMNKDPEILSWT-IPPSIEKTS 6800 Query: 938 LTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIA 997 +++ + +P +T PVS T+ T PS P++ L +P+ T T+ Sbjct: 6801 FSSS-LMPSPAMTSPPVSSTLPKTIHTTPS----------PMTSLLTPSLVMTTDTL--- 6846 Query: 998 DSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057 P T N +HE TT+ TT + A HP + AA Sbjct: 6847 -----GTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAM---HPSTS---------TAAT 6889 Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA--TTATSNMAGQHGCSNPPCETHETG 1115 ++ T++ G + S V S T TT+T TT +++M+ + E+ + Sbjct: 6890 NVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSL 6949 Query: 1116 TTNTATTAMSSVGANHQRDARRACA---AGTPAVIRISVATGALEAAQGSKSQCQTRQTS 1172 T T++S A+ D + GT A + + T + + SQ Sbjct: 6950 TPGLRETSISQ-NASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEI 7008 Query: 1173 ATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR 1232 +T T + A+ + + P+ G S + L ++K + + S R Sbjct: 7009 STRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTL---TQR 7065 Query: 1233 HSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCP---SATVTQVC 1289 H+ T M+R G + +P E +PS+ ++ +L A P S+T+ Sbjct: 7066 FPHSEMTTLMSRGP-GDMSWQSSPSLE-----NPSSLPSLLSLPATTSPPPISSTLPVTI 7119 Query: 1290 SNPPCETHETGTTNTATTSNA--GSAQRVCSNPPCETHET--------GTTHT----ATT 1335 S+ P T++ TT++ S + V S+PP +H + TT+T +T Sbjct: 7120 SSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPST 7179 Query: 1336 ATSNGGTGQPEGGQQPPAGRPCETHQTTSTG----------TTMSVSVGALLPDATSSHR 1385 T+ P G + P+ ++ + +T TT+++S L + Sbjct: 7180 NTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKE 7239 Query: 1386 TV--------ESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTA-TTV 1436 ++ E+G V + ++ A + ++ T + + T + +A +T+ Sbjct: 7240 SISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTM 7299 Query: 1437 TSNMSSNQ-----DPPPAASDQGEVE-STQGDSVNITSSSAITTTVSSTLTRAVT--TVT 1488 +S+ + P ++ E+ TQ TS S T S+T + +T T+T Sbjct: 7300 LPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMT 7359 Query: 1489 QSTP--------------VPGPSVPPPEE-----------LQVSPGP-RQQLPPRQLLQS 1522 Q P VP PS P EE +SP P LP S Sbjct: 7360 QRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSS 7419 Query: 1523 AS-TALMG----ESAEVLSASQTPELPAAVDLSST------------------------- 1552 AS T+L+ ++ EVL AS PE + LSST Sbjct: 7420 ASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAV 7479 Query: 1553 ---GEPSSGQESAGS-----------AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG 1598 G SSG ES S + + T+ + + LS +++ +E + Sbjct: 7480 TKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASS 7539 Query: 1599 TTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGE-PMDTSE 1657 TT + T EE ++ A +T ++ + ++ ++ G + M Sbjct: 7540 LTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDI 7599 Query: 1658 AAATVTQAELGHLSAEGQEGQATT 1681 + T+ + + E + TT Sbjct: 7600 SIGTIPRISASSVLTESAKMTITT 7623 Score = 103 bits (258), Expect = 1e-21 Identities = 247/1113 (22%), Positives = 403/1113 (36%), Gaps = 152/1113 (13%) Query: 379 SLEVSWGAVATADSYLLQLQKYDIPATAATATS---PTPNPVPSVPANPPKSPAPAAAAP 435 SL S V + L L ++ T + ATS + VP+ +P S Sbjct: 11044 SLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVT 11103 Query: 436 AVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQAT 495 + + +T I +L ++ P TT ++ V SS + + G+ L VT +A Sbjct: 11104 SSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSL-VTSSRAV 11162 Query: 496 TGTPLVTMRPASQAGKAPVTVTSL----PAGVRMVVPTQSAQGTVIGSSPQMSGMAALAA 551 T T + T+ +S P T TSL A + +PT + TV G + + Sbjct: 11163 TSTTIPTLTISSD---EPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSET 11219 Query: 552 AAAATQKIPPSSAPTVLSVPA-----GTTIVKTMAVTPGT--TTLPATVKVASSPVMVSN 604 +A + + S T+ S A +++V T+ V+ G T + A S + Sbjct: 11220 SAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPR 11279 Query: 605 PATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTI-TL 663 +R + + ++V+S S+ I T G V +VT+ ++ T T+ Sbjct: 11280 TTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIPGVL--TSLVTSSGRDISATFPTV 11337 Query: 664 VKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILK 723 +SP ++ +++ V + V + S T I T A + Sbjct: 11338 PESPHESEATASWVTH-----PAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFP 11392 Query: 724 LVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGA 783 +T + P + T+Q + +GT T + I +++ S+ +P TTT I S T + Sbjct: 11393 TITVSPDVPDMV--TSQVTSSGT-DTSITIPTLTLSSGEPETTT--SFITYSETHTSSAI 11447 Query: 784 TGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPG 843 + SPG ++T+ V++SGT + T P + + T + L P + Sbjct: 11448 PTLPVSPGASK---MLTSLVISSGTDS----TTTFPTLTETPYEPETTAIQLI-HPAETN 11499 Query: 844 TIL-RTVPM---GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGG 899 T++ RT P PV +++ P ++ V TT+ + TSL + G Sbjct: 11500 TMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAV-----STTTISPDMSDLVTSLVPSSG 11554 Query: 900 HSTSASLATPITTLGTIATLSSQVINP--TAITVSAAQTTLTAAGGLTTPTITMQP---- 953 TS + T T T ++ + +P T+ TVS + G T P++ P Sbjct: 11555 TDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDT 11614 Query: 954 -VSQPTQVTLITAPSGVEAQPVHDLPVSILASPT-TEQPTATVTIADSGQGDVQPGTVT- 1010 PT + P V +Q + A PT T P T A S PGT T Sbjct: 11615 RSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSA---THPGTQTG 11671 Query: 1011 ------LVCSNPP-----CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASL 1059 V S+ P TH T+ + T + P T V R EA++++ Sbjct: 11672 FTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAV 11731 Query: 1060 VTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNT 1119 +T+ +P T ++ ATS + P TH G Sbjct: 11732 LTTI-------------SPGAPEMVTSQITSSGAATS--------TTVPTLTHSPGMPE- 11769 Query: 1120 ATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMT 1179 TTA+ S H R + ++S T +L G+++ T TS+ T Sbjct: 11770 -TTALLS---THPRTETSKTFPASTVFPQVSETTASLTIRPGAETS-TALPTQTTSSLFT 11824 Query: 1180 VMATG-APCSAGPLLGPS-------MAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAG 1231 ++ TG + P P ++ PG + + + LS L L A Sbjct: 11825 LLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLS----LGLLETTGLLAT 11880 Query: 1232 RHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPST--TVTVTALEALLCPSATVTQVC 1289 S ST+ +T + ++P L S +T TVT+ PS T Sbjct: 11881 SSSAETSTSTLTLT--------VSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSV--- 11929 Query: 1290 SNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSN-GGTGQPEGG 1348 P TGTT T S PP +H G + T T+ T G Sbjct: 11930 GPPEFSRTVTGTTMTLIPSE-------MPTPPKTSHGEGVSPTTILRTTMVEATNLATTG 11982 Query: 1349 QQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALL 1408 P + T TT + G+L T+ G+ A+ SVT + Sbjct: 11983 SSPTVAK---------TTTTFNTLAGSLFTPLTT------PGMSTLASESVTSRTS---- 12023 Query: 1409 APFPTQRVCSNPPCETHETGTTHTATTVTSNMS 1441 + + S T T+T VTS S Sbjct: 12024 --YNHRSWISTTSSYNRRYWTPATSTPVTSTFS 12054 Score = 101 bits (252), Expect = 7e-21 Identities = 268/1280 (20%), Positives = 456/1280 (35%), Gaps = 186/1280 (14%) Query: 401 DIPATAATATSPTPNPVPSVPANPPKSPAPAAA---APAVQPLTQVGI-TLLPQAAPAPP 456 + P +A +TS P + P++ A + A +V L++ + + P P Sbjct: 2089 EFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPM 2148 Query: 457 TTTTIQVLPTVPGSSISVPT--AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPV 514 T+ + + S + P+ A + G ++ P T LV+ R K P Sbjct: 2149 AITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLP---TSESLVSFR----MNKDPW 2201 Query: 515 TVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGT 574 TV S+P G PT + + ++ +S G++ +A+ T S PTV P+ Sbjct: 2202 TV-SIPLGSH---PTTNTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPD 2257 Query: 575 TIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIIT 634 T V T++ P TT + + SS +++ T + +S S T P IT Sbjct: 2258 TEVTTISHFPEKTT--HSFRTISS---LTHELTSRVTPIPGDWMSSAMSTKPTGASPSIT 2312 Query: 635 VHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQT 694 + + T+T A + T+T T +S+ V+T Sbjct: 2313 LGERRTITSAAPTTSPIVLTASFTETST---------------------VSLDNETTVKT 2351 Query: 695 SAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASG--AGTKPTILG 752 S + T + + L +I ++ D T I+ T SG A + P++ Sbjct: 2352 SDILDARKTNELPSDSSSSSDLINTSIAS--STMDVTKTASISPTSISGMTASSSPSLFS 2409 Query: 753 ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGT---- 808 T+ T T S + G + V +P P T IT V TS Sbjct: 2410 SDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFT-ITHPVETSSALLAW 2468 Query: 809 GAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGT--------------ILRTVPMGGV 854 P + + + T G+ + + + PGT L+T P G Sbjct: 2469 SRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEA 2528 Query: 855 RLVTPVTV---SAVKPAVTTLVVKGTTGVTTLGTVT-----------GTVSTSLAGAGGH 900 + T+ +A P ++ VV G++ + +T T +T +GA Sbjct: 2529 HSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWE 2588 Query: 901 STSASLATPITTLGTIATLSSQVINPTAI---TVSAAQTTLTAAGGLTTPTITMQPVSQP 957 +++ + + T + TL+S+++ I TVS + + G L+ + P Sbjct: 2589 TSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTP 2648 Query: 958 TQVTLITAPSGVEAQPVHDLPVSILASPTT-EQPTATVTIADSGQGDVQPGTVTLVCSNP 1016 T P+ A P+ +AS + P T+T++++ GD V SNP Sbjct: 2649 AIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGD---ALVLKTVSNP 2705 Query: 1017 PCETHETGTTNTATTTVVANLGGHPQPTQ-VQFVCDRQ---EAAASLVTSTV-GQQNGSV 1071 + G T T HP T + V R E + ++ ST+ GS+ Sbjct: 2706 --DRSIPGITIQGVTESPL----HPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSL 2759 Query: 1072 VRVCSNPPCETH---------ETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTAT- 1121 V S+ ET E + TT + MA G + TH TGT ++ Sbjct: 2760 VFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSG--STHSTGTKTFSSL 2817 Query: 1122 ---------TAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTS 1172 TAMS + N + G P V S +G L S S + + Sbjct: 2818 PLTMNPGEVTAMSEITTNRLTATQSTAPKGIP-VKPTSAESGLLTPVSASSSPSK----A 2872 Query: 1173 ATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR 1232 S T G P S L + P L S+ + S+ +P Sbjct: 2873 FASLTTAPPTWGIPQST---LTFEFSEVP--------SLDTKSASLPTPGQSLNTIPDSD 2921 Query: 1233 HSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNP 1292 S A ++++++S RM +++ S +T E SA+ + P Sbjct: 2922 ASTA--SSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEG----SASPSMAGHEP 2975 Query: 1293 PCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPP 1352 T TG A+ S + +P + +T A+ T+ TGQ Sbjct: 2976 RVPTSGTGDPRYASESMS------YPDPSKASSAMTSTSLASKLTTLFSTGQ-------- 3021 Query: 1353 AGRPCETHQTTSTGTTMSVSVGALLPDATSSHRT-VESGLEVAAAPSVTP--QAGTALLA 1409 A R + S T S L P A++S +T + G +A P++ Q L+ Sbjct: 3022 AARSGSSSSPISLSTEKETSF--LSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLS 3079 Query: 1410 PFPTQRVCSNPPCE-------THETGTTHTATTVTSNMSSN-------QDPPPAASDQGE 1455 P T + P E E GTT T+T S P + + Sbjct: 3080 PTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKS 3139 Query: 1456 VESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEE-----LQVSPGP 1510 T S+++ + +++ T TL + +Q+ P EE SPG Sbjct: 3140 SPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGS 3199 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSAS--QTPELPAAVDLSSTGEPSSGQESA---GSA 1565 + +++ S ++ E + S +TPE V + +T EP + Q +A GS Sbjct: 3200 PEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPE--TTVPMETTVEPVTLQSTALGSGST 3257 Query: 1566 VVATVVVQPPPPTQSEVDQL 1585 ++ + PT+S + + Sbjct: 3258 SISHLPTGTTSPTKSPTENM 3277 Score = 97.4 bits (241), Expect = 1e-19 Identities = 312/1531 (20%), Positives = 543/1531 (35%), Gaps = 274/1531 (17%) Query: 405 TAATATSPTPNPVPS---VPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTI 461 T A P+ N S +P++ +SP+ A A T +P T+ Sbjct: 7170 TNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKAT------------SPMFITST 7217 Query: 462 QVLPTVPGSSISVPTAARTQ-----GVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTV 516 Q TV S+ +R Q + L+ TG T + + T S+ T Sbjct: 7218 QEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTE 7277 Query: 517 TSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTI 576 S T S++ ++ GS+ + + + T+KI +L+ + TI Sbjct: 7278 IS------RTEVTSSSRTSISGSAE-----STMLPEISTTRKIIKFPTSPILAESSEMTI 7326 Query: 577 VKTMAVTPGTTTLPA-TVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635 KT PG+T+ T+ +++P +V +T + +++ T VS RP Sbjct: 7327 -KTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLP 7385 Query: 636 HKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTS 695 + + +Q + V+ T+ P S SA +++L V T+ + S Sbjct: 7386 VEETSPPSSQLSLSAMISPSPVSSTL-----PASSHSSSASVTSLLTPGQVKTTEVLDAS 7440 Query: 696 AVTGQAS-------------TGPVTQIIQTKGPLPAGTILKLVTSADG--KPTTIIT--- 737 A +S T VT + P + K+ TS+ G P++++ Sbjct: 7441 AEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSE 7500 Query: 738 TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPIT 797 TT+A+ A +I+G +SVS T T I++ P S++ T+ T + + + Sbjct: 7501 TTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEAN 7560 Query: 798 IITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLV 857 + +KV TGA ++ + G Q T+ + + +G + Sbjct: 7561 TVLSKV---STGATTEVSRTEAISFSRTSMSGPEQ----------STMSQDISIGTI--- 7604 Query: 858 TPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIA 917 P ++ V + T+ T TG ++L + + + AT + + T + Sbjct: 7605 ---------PRISASSVLTESAKMTITTQTGPSESTLES----TLNLNTATTPSWVETHS 7651 Query: 918 TLSSQVINPTAITVSAAQTTLTAAGGLTTPTITM----QPVSQPTQVTLITAPSGVEAQP 973 + +P T GG++ P+ P S P + +T+P V Sbjct: 7652 IVIQGFPHPEMTTSMG-----RGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTF 7706 Query: 974 VHDLPVSIL--ASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTT--NTA 1029 + +P S L S T P T I + +PGT + S+ +HE TT +TA Sbjct: 7707 LAHIPPSPLPVTSLLTSGPATTTDILGT---STEPGTSS--SSSLSTTSHERLTTYKDTA 7761 Query: 1030 TTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTN 1089 T V HP ++ T++ G ++ S V S+P C T G T+ Sbjct: 7762 HTEAV-----HP---------STNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTS 7807 Query: 1090 TATTA-----TSNMAGQHGCSNPPCETHETGTTNTAT-TAMSSV------GANHQRDARR 1137 T+ T + + S P +G+ T++ T MS+V GA + Sbjct: 7808 VLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKED 7867 Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPS- 1196 + PA IS + S S T T T T GA L S Sbjct: 7868 VTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHT-SPLGATTQGTSTLDTSS 7926 Query: 1197 -----MAREPGGRSPAFVQLAPLSSK----VRLSSPSIKDLPAGRHSHAVSTAAMTRSSV 1247 M + + Q++ L + V SP + + S S A + S V Sbjct: 7927 TTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPV 7986 Query: 1248 GAGEPRM-----APVCESLQGGSPSTT-------VTVTALEALLCPSATVTQVCSNPPCE 1295 + P PV L G TT VT A L ++ S + Sbjct: 7987 SSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTD 8046 Query: 1296 THETGTTNTATTSNAGS------------AQRVCSNPPCETHETGTTHTATTATSNGGTG 1343 T +T ++ T ++ G+ A S T T + +TS G Sbjct: 8047 TEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGFF 8106 Query: 1344 QPEGGQQPPAG------RPCETHQTTSTGTTMS-----VSVGALL----PDATSSHRTVE 1388 + Q P R + + TS T MS V GA + TSS RT Sbjct: 8107 ETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSI 8166 Query: 1389 SGLEVAAAPSVTPQAGTALLAPFPTQRVC-----------SNPPCETHETGTT------- 1430 SG A +V+P+ T + PT + ++PP T E+ T Sbjct: 8167 SGF---AQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTP 8223 Query: 1431 ---HTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTV 1487 T +TVT S ++ + G++ SV TSS++ ++ +T + + + Sbjct: 8224 NWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSS 8283 Query: 1488 TQSTPVPGPSVP-----------PPEELQVSPGP-------------------------- 1510 T P S+P + + +S P Sbjct: 8284 TLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTE 8343 Query: 1511 RQQLPPRQLLQSASTALMGESAE--VLSASQTPELPAAVDLSST-GEPSSGQESAGSAVV 1567 Q + + T++ G ++ VLS S+TP+ + + + T GE S ++ Sbjct: 8344 DMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFET 8403 Query: 1568 ATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQA--- 1624 + + ++P S + + S + + + + T V E++ T + + Sbjct: 8404 SRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSG 8463 Query: 1625 ---------AATEEAQALAIQAVL-QAAQQAV-MGTGEPMDTSEAAATVTQAELGHLSAE 1673 +TE L+ ++ ++A+ A+ + TG P TSE T+ + S Sbjct: 8464 PDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGTLTLDTSTTTFWS-- 8521 Query: 1674 GQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPT--EALAPADSLNDPAIESN 1731 G +T + E+ L + LP+ EA + + SL+ PA+ S Sbjct: 8522 ---GTHSTASPGFSHSEMTTL-----MSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTS- 8572 Query: 1732 CLNELAGTVPSTVALLPS--TATESLAPSNT 1760 T+P +++ P TA +L P T Sbjct: 8573 --TSFFSTLPESISSSPHPVTALLTLGPVKT 8601 Score = 95.1 bits (235), Expect = 6e-19 Identities = 354/1655 (21%), Positives = 588/1655 (35%), Gaps = 338/1655 (20%) Query: 376 NTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSP---TPNPVPSVPANPPKSPAPAA 432 +TN+ + GA A+++S I T A+ P TP PS+ + S A A Sbjct: 1245 STNTPSIHLGAHASSES------PSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMA 1298 Query: 433 AAPAVQPL------TQVGITLLPQA---APAPPTTTTIQVLPTVPGSSISVPTAARTQGV 483 + P T G T P P T++ QV + SV T T+ Sbjct: 1299 YSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQV-----STPHSVRTLRTTENH 1353 Query: 484 PAVLKVTGPQATTGTPLVTMRP--ASQAGKAPVTVTSLPAGVRMVVP----------TQS 531 P T P A +G+P ++ P S A KA + ++ TQS Sbjct: 1354 PKTESAT-PAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQS 1412 Query: 532 AQG---TVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTT 588 A G VI +SP + ++ T +P P VL+ TTI MA T+ Sbjct: 1413 APGPVSVVIPTSPTIG-----SSTLELTSDVP--GEPLVLAPSEQTTITLPMATWLSTSL 1465 Query: 589 LPATVKVASSPVMVSNPATRM--------LKTAAAQVGTS---VSSATNT---------- 627 T ++AS+ + +S+P++ M + T + ++ S S+ NT Sbjct: 1466 ---TEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLG 1522 Query: 628 ----------STRPI--ITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSA 675 +T PI +T + + + QAQ + T +K S+P SA Sbjct: 1523 IRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPA-SA 1581 Query: 676 LISNLGKVMSVVQTKPVQTSAVTG--QASTGPVTQIIQTKGPLPAGTILKLVTSADGKPT 733 S+L +V + T+ +S T + ST +++ I+T GP T+ P Sbjct: 1582 SPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIET-GP----------TNIQSTPP 1630 Query: 734 TIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI---IKTIPMSAIITQAGATG--VTS 788 TTT +S +G LGI+ + T+ P T+ ++ +A ++ AG G VTS Sbjct: 1631 MDNTTTGSSSSGVT---LGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTS 1687 Query: 789 SPG---------IKSPITIITTKVMT-SGTGAPAKI-------ITAVPKIATGHGQQGVT 831 +PG + S ++ TT+ +T S G+ ++ +++ + + G Q T Sbjct: 1688 APGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMST 1747 Query: 832 QVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAV-KPAVTTLVVKGTTGVTTLGT----- 885 + L +P P + VT V S + K + T T T LG+ Sbjct: 1748 SIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTG 1807 Query: 886 -------------------VTGTVSTSLAGA-----------GGHSTSASLATPITTLGT 915 VT +S +L+ A G H++SA +L T Sbjct: 1808 KEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNT 1867 Query: 916 IATLSSQVINP---------------TAITVS------------------AAQTTLTAAG 942 T +S++ N T++T + A+TTLT+ Sbjct: 1868 GVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTP 1927 Query: 943 G-----LTTP-----------------------TITMQPVSQPTQVTLITAPSGVEAQPV 974 G LT P +T P++ PT V T QP+ Sbjct: 1928 GNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPL 1987 Query: 975 HDL---PVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031 H + VS+ T + V+ + + + V G+ T S+P ++ + Sbjct: 1988 HAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSST---SSP--------YSSASLE 2036 Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 ++ + + T + + ++++ + S SNP T E + A Sbjct: 2037 SLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAA 2096 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 +T+ + NP ETH G NTA + +++ DA S Sbjct: 2097 STSAAKQ------RNPETETH--GPQNTAASTLNT-------DA--------------SS 2127 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 TG E G+ + A ++ V + +A P LG A G + + L Sbjct: 2128 VTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLG--TASSAGTKLTRTISL 2185 Query: 1212 APLSSKVRL---SSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPST 1268 S V P +P G H + ++ +S AG P ++ V + Sbjct: 2186 PTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNS--AGPPGLSTVASDVIDTPSDG 2243 Query: 1269 TVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTAT---TSNAGSAQRVCSNPPCETH 1325 ++ + P VT + P TH T ++ T TS + T Sbjct: 2244 AESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTK 2303 Query: 1326 ETGTTHTAT-----TATSNGGTGQP---EGGQQPPAGRPCETHQTTSTGTTMSVSVGALL 1377 TG + + T T TS T P + + T T + L Sbjct: 2304 PTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNEL 2363 Query: 1378 PDATSSHRTV------ESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTH 1431 P +SS + S ++V S++P + + + A S+ P T TT Sbjct: 2364 PSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRP--QVPTSTTE 2421 Query: 1432 TATTVTSNMSSNQDPPPAASDQGEVEST----------QGDSVNITSSSAITT--TVSST 1479 T T + ++SSN S+ G ST + S + S + T T+ ST Sbjct: 2422 TNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVST 2481 Query: 1480 LTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSA-- 1537 T + T S V SVP P S G LP L+ T+ GE+ +L++ Sbjct: 2482 DTASGENPTSSNSVV-TSVPAP-GTWTSVGSTTDLPAMGFLK---TSPAGEAHSLLASTI 2536 Query: 1538 ----SQTPELPAAV--DLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQEL 1591 + TP L AAV S+T E S S A+ ++ P + + + + P+ L Sbjct: 2537 EPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESL 2596 Query: 1592 MAEAQAGTTTL----MVT--------GLTPEELAVTAAAEAAAQAAATEEAQALAIQAVL 1639 + + TTL +VT P + T A+ + A+ + A Sbjct: 2597 LVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATE 2656 Query: 1640 QAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQ 1699 + A P+ T + + T E +E G A + V + Q Sbjct: 2657 PTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQG 2716 Query: 1700 LQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSN 1759 + E+ P++ +AP ++ + +I AGT S V S +E+ A Sbjct: 2717 VTESPLHPSSTS-PSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSENSETTA--- 2772 Query: 1760 TFVAPQPVVVASPAKLQAAAT--LTEVANGIESLG 1792 +V S A L+ A+ LT + G+ S G Sbjct: 2773 --------LVDSSAGLERASVMPLTTGSQGMASSG 2799 Score = 94.7 bits (234), Expect = 8e-19 Identities = 310/1528 (20%), Positives = 535/1528 (35%), Gaps = 218/1528 (14%) Query: 405 TAATATSPTPN-PVPSVPANPP--KSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTI 461 T A +T+ N PV PA S P P+ L + L P+ P T++ Sbjct: 195 TFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSPKGTPNSRGETSL 254 Query: 462 QVLPTVPGSSISVP-----------TAARTQGVPAVL--KVTGPQATTG----TPLVTMR 504 +++ + G S P T+A +VL K++ +G +PL Sbjct: 255 ELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGV 314 Query: 505 PASQAGKAP-------VTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQ 557 P ++A P +T+++ V T S+ GT S+ Q + A A T Sbjct: 315 PEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETM 374 Query: 558 KIPPSSAPTVLSVPAGTTIVKTMAV----TPGT---TTLPATVKVASSPVMVSNPATRML 610 IP T I KT+A +PGT T+ A + S +VS Sbjct: 375 DIP------------STHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHH 422 Query: 611 KTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVG--GVTKTITLVKSPI 668 T+ G NTS P+ T +++++ T+V G T + ++SP Sbjct: 423 STS----GKETEGTLNTSMTPL------ETSAPGEESEMTATLVPTLGFTTLDSKIRSPS 472 Query: 669 SVPGGSALI------SNLGKVMS---------VVQTKPVQTSAVTGQASTGPVTQIIQTK 713 V S G+ S +++ TS + S Q + + Sbjct: 473 QVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQ 532 Query: 714 GPLPAGTILKLVTSADGKPTTI---ITTTQASGAGTKPTILGISSVSPSTTKP------- 763 T + T T++ ITT+ S + G +++ S+TK Sbjct: 533 HTQWVETSPSMKTERPPASTSVAAPITTSVPS------VVSGFTTLKTSSTKGIWLEETS 586 Query: 764 -----GTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGT---------G 809 G +T T A+ T TG +S+ G + ++T +S T G Sbjct: 587 ADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNG 646 Query: 810 APAKIITAVPKIATGHGQQG--------VTQVV-----LKGAPGQPGTILRTVPMGGVR- 855 P + AV K A G G V+ V+ L+ + + GT L P+ Sbjct: 647 VPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHP 706 Query: 856 LVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGT 915 +P SA ++T + ++ V+ T + S H ++S+ T + T Sbjct: 707 FSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFS-----HHKATSSITTGTPEIST 761 Query: 916 IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVH 975 SS V++ ++T+S A T+ T+P P + T +++T + E Sbjct: 762 KTKPSSAVLS--SMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSP 819 Query: 976 DL-PVSILASPTTEQPTATVTIADSGQGDV-----------QPGTVTLVCSNPPCETHET 1023 ++ P L S ++E P+ + SG G T SNP ET Sbjct: 820 NIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPET 879 Query: 1024 GTTNTATTTVVANLGGHPQPTQVQFVC-DRQEAAASLVTSTVGQQNGSVVRVCSNP-PCE 1081 + TT ++ PT + Q +++ LV+ + SV + P Sbjct: 880 SVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKI 939 Query: 1082 THETGTTNTATTATSNMAGQHGCSNPPCET-------HETGTTNTATTAMSSVGANHQRD 1134 +H TGT AT + +N + + P T +TG + TT +S Sbjct: 940 SHLTGT---ATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTS-------- 988 Query: 1135 ARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLG 1194 A A + +S T ++ + S + T T+ T + A S +G Sbjct: 989 -----ATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIG 1043 Query: 1195 PSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTA-AMTRSSVGAGEP- 1252 E GR + + L SS + D + S ++S + + + + G+ P Sbjct: 1044 KGYITE--GR----LDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPG 1097 Query: 1253 RMAPVCESLQGG-----SPSTTVTVTALEALLCPSATVTQVCSNPPCETHET-------- 1299 R + ++ S T+ + L P T T S P T Sbjct: 1098 RTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSS 1157 Query: 1300 --GTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPC 1357 T T S+ S QRV ++ +T ET + ++ T Sbjct: 1158 PSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTL 1217 Query: 1358 ETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAA-----APSVTPQAGTALLAPFP 1412 T S T++ S G L +T T + + A +PS +++ P Sbjct: 1218 VPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKP-G 1276 Query: 1413 TQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAI 1472 + + P ETH H +T + SS P A + ST + IT++ Sbjct: 1277 SYTPLTFPSIETH----IHVSTARMA-YSSGSSPEMTAPGETNTGSTWDPTTYITTTDPK 1331 Query: 1473 TTTVSSTLT-RAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGES 1531 T+ + T +V T+ + P P SP S+S L + Sbjct: 1332 DTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKI-----------SSSPNLTSPA 1380 Query: 1532 AEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLS--LPQ 1589 + + + T E + + E SSG E+ + +VV+ P S +L+ +P Sbjct: 1381 TKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPG 1440 Query: 1590 ELMAEAQAGTTTL---MVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAV 1646 E + A + TT+ M T L+ A+ + + ++ + + + + Sbjct: 1441 EPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELS 1500 Query: 1647 MGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIV-LTQQELAALVQQQQLQEAQA 1705 + +T LG + + G+ G TT+PI LT + + Q Q+ + Sbjct: 1501 KSEADTSAIRNTDSTTLDQHLG-IRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLS 1559 Query: 1706 QQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQ 1765 T++L S+ A S+ L E+ + T S AT PS ++ + Sbjct: 1560 ATMSPTHVTQSLKDQTSIPASASPSH-LTEVYPEL-GTQGRSSSEATTFWKPSTDTLSRE 1617 Query: 1766 PVVVASPAKLQAAATLTEVANGIESLGV 1793 + P +Q+ + G S GV Sbjct: 1618 --IETGPTNIQSTPPMDNTTTGSSSSGV 1643 Score = 91.7 bits (226), Expect = 7e-18 Identities = 271/1351 (20%), Positives = 461/1351 (34%), Gaps = 194/1351 (14%) Query: 456 PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVT 515 P TT+ V T+P S S + + P ++K T GT L + T Sbjct: 10028 PVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSL--------SPNLSGT 10079 Query: 516 VTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT 575 + A + T+ + SS ++ + ++ + S P+ + P GT Sbjct: 10080 SVEILAASEVTTDTEKIHPS---SSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTP 10136 Query: 576 IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635 +MA T +T++PA + + T + + TS + TNT + P T Sbjct: 10137 --SSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTH 10194 Query: 636 HKSGTVT---------------VAQQAQVVTTVV------GGVTKTITLVKSP-----IS 669 + T +Q ++ ++ +T++ + P +S Sbjct: 10195 LLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMS 10254 Query: 670 VPGGSALISN----LGKVMSVVQTKPVQTSAVTGQASTG----------PVTQIIQTKGP 715 V + +S + +S P + A+T A+TG P ++ G Sbjct: 10255 VTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGD 10314 Query: 716 LPAGTILKLVTSADGKP--TTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIP 773 TI + + S+ P ++ TTT +S T P + I+S S + + T+ ++ Sbjct: 10315 ATLSTIAESLPSSTPVPFSSSTFTTTDSS---TIPALHEITSSSATPYRVDTSLGTESST 10371 Query: 774 MSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQ-QGVTQ 832 + +S PG S I+ T++ S VP ++T + G+ + Sbjct: 10372 TEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIME 10431 Query: 833 VVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVST 892 + K P + G +R V S + L GT + T T T +T Sbjct: 10432 HITK-IPNE------AAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTT 10484 Query: 893 SLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAI-----------------TVSAAQ 935 +L + + S+ TP TLGT+ L++ + + I T S+ Sbjct: 10485 ALKTTSRATLTTSVYTP--TLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLA 10542 Query: 936 TTLTAAGGLTTPTITMQPVSQPTQVTL-ITAPSGVEAQPVHDLPVSILASPTTEQPTATV 994 T+L A P T ++ ++ T + + SG E PV + L ++E T Sbjct: 10543 TSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPV----IQTLDVSSSEPDTTAS 10598 Query: 995 TIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQE 1054 + + T+ V P H T ++T T PT + + Sbjct: 10599 WVIHPAE------TIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNIS--PSELD 10650 Query: 1055 AAASLVTSTVGQQNGSVVRVCSNPPCE--------THETGTTNT--------------AT 1092 A LVT + G + + P E TH T++T AT Sbjct: 10651 ALTPLVTIS-GTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDAT 10709 Query: 1093 TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRD-ARRACAAGTPAVI---- 1147 + + G S P T G + T+ ++S G + + G P I Sbjct: 10710 PSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLV 10769 Query: 1148 -------RISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE 1200 ++ T + A +A ++T T +P P S+ Sbjct: 10770 THPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSP--GEPATTVSLVTH 10827 Query: 1201 PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSH-AVSTAAMTRSSVGAGEPRMAPVCE 1259 P SP P ++ + S S P+ SH A S++A+ +V P + Sbjct: 10828 PAQTSPT----VPWTTSIFFHSKS-DTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLV 10882 Query: 1260 SLQGGSPSTTVTVTAL---EALLCPSATVT---QVCSNPPCETHETGTTNTATTSNAGSA 1313 + STT+ + L E PS + + S P T G T+ S Sbjct: 10883 TSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSR 10942 Query: 1314 QRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSV 1373 + P T G T + ++ GT E G P P TS + Sbjct: 10943 AVTSTTIPILTFSLGEPETTPSMATSHGT---EAGSAVPTVLPEVPGMVTSLVASSRAVT 10999 Query: 1374 GALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTA 1433 LP T S P TP T+ A S P + E T+ Sbjct: 11000 STTLPTLTLS----------PGEPETTPSMATSHGA-----EASSTVPTVSPEVPGVVTS 11044 Query: 1434 TTVTSNMSSNQDPPPAASDQGEVEST--QGDSVNITSSSAI-TTTVSSTLTRAVT-TVTQ 1489 +S+ ++ P GE+E+T S +SSA+ T TVS ++ VT VT Sbjct: 11045 LVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTS 11104 Query: 1490 STPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDL 1549 S V ++P L +S + P A++ + S+ VL+ S PE+P V Sbjct: 11105 SRAVTSTTIP---ILTLSSSEPETTP-----SMATSHGVEASSAVLTVS--PEVPGMVTS 11154 Query: 1550 SSTGEPSSGQESAGSAVVATVVVQPPPP-------TQSEVDQLS-LPQELMAEAQAGTTT 1601 T + S + T+ + P T SE +S +P ++ G T Sbjct: 11155 LVT-----SSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVT 11209 Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAA- 1660 +VT E A + A++Q + A + TGEP Sbjct: 11210 SLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTH 11269 Query: 1661 -TVTQAELGHLSAEGQEGQATTIPIVLTQQE 1690 + + L ++ + T+P +T E Sbjct: 11270 PAESSSTLPRTTSRFSHSELDTMPSTVTSPE 11300 Score = 87.4 bits (215), Expect = 1e-16 Identities = 277/1325 (20%), Positives = 494/1325 (37%), Gaps = 192/1325 (14%) Query: 402 IPATAATATSPTPNPVPSVPANP--------PKSPAPAAAAPAVQPLTQVGITLLPQAAP 453 + +T + S +P PV S+ + KS P +PA T V I A Sbjct: 7986 VSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEIL-----AT 8040 Query: 454 APPTTTTIQVLPTVPGSSISVPTAARTQGVPAVL-------KVTGPQATTGTPLVTMRPA 506 + TT T + P+ + V T++ + + KVT P T T T Sbjct: 8041 SEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVST 8100 Query: 507 SQAGKAPVT------VTSLPAGVRMVVPTQSAQGTVIGS--SPQMSGMAALAAAAAATQK 558 S G + +SL G+R T S++GT + + S +SG+ A A + + Sbjct: 8101 STPGFFETSRIQTEPTSSLTLGLRK---TSSSEGTSLATEMSTVLSGVPTGATAEVSRTE 8157 Query: 559 I-----------------PPSSAPTVLSVPAGTTI-------VKTMAVTPGTTTLPA-TV 593 + P +S T+ +P + + +KT PG+T TV Sbjct: 8158 VTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTV 8217 Query: 594 KVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV 653 ++++P V +T + + +++ T VS + P + + + + + TT Sbjct: 8218 DISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTS 8277 Query: 654 VGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTK 713 V+ T+ S+P S L L V+ T + S G +ST ++ + Sbjct: 8278 PSPVSSTLVEDFPSASLPVTSLLNPGL-----VITTDRMGISREPGTSSTSNLSSTSHER 8332 Query: 714 GPLPAGTILKLVTSADGKPTTIITTTQA----SGAGTKPTILGISSVSPSTTKPGTTTII 769 T+ V + D +P+T T SG ++ ++L S +T+ GTT + Sbjct: 8333 ----LTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTM 8388 Query: 770 KTIPMSAIITQAGATG---VTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHG 826 +S + T + + + S + ++ S + +++ VP AT Sbjct: 8389 GETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEV 8448 Query: 827 QQGVTQVVLKGAPGQPG----TILRTVPMGGV-RLVT-PVTVSAVKPAVTTLVVKGTTGV 880 + T+V+ G TI + + RL T P+ + + A+T + G+ G Sbjct: 8449 SR--TEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAIT--IETGSPGA 8504 Query: 881 TTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTA 940 T+ GT+T ST+ +G HST A+P + + TL S+ Sbjct: 8505 TSEGTLTLDTSTTTFWSGTHST----ASPGFSHSEMTTLMSRTPG--------------- 8545 Query: 941 AGGLTTPTITMQPVSQPTQV-TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADS 999 P ++ V + + V + +++P+ LP SI +SP TA +T+ Sbjct: 8546 ----DVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSP--HPVTALLTL--- 8596 Query: 1000 GQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASL 1059 G V+ + S P ET ++ + ++A + DR++ S Sbjct: 8597 --GPVKTTDMLRTSSEP--ETSSPPNLSSTSAEILAT---------SEVTKDREKIHPSS 8643 Query: 1060 VTSTVGQQNGSVVRVCSNPPCETHETGTTN-TATTATSNMAGQHGCS-NPPC--ETHETG 1115 T V G+V+ +P + TT T+ AT++ G S + P ET T Sbjct: 8644 NTPVVNV--GTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQ 8701 Query: 1116 TTNTATTAMSSVGANHQRDA---RRACAAGTPAVIRISVA-TGALEAAQGSKSQCQTRQT 1171 T++ T+ + + + + + R A +G P V+ T AL + S Sbjct: 8702 PTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTI 8761 Query: 1172 SATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAG 1231 S +T T+ P + ++ + G + L + R S P Sbjct: 8762 SPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATH 8821 Query: 1232 RHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSN 1291 R H+ T M+R P V ++ PS+ V+++A+ + +T ++ + Sbjct: 8822 RSPHSGMTTPMSRGPEDVSWPSRPSVEKT---SPPSSLVSLSAVTSPSPLYSTPSESSHS 8878 Query: 1292 PPCETHETGTTNTATTSNA--GSAQRVCSNPP---CETHETGTTHTAT-----------T 1335 P T T++ S + V ++PP + E+ T AT T Sbjct: 8879 SPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENT 8938 Query: 1336 ATSNGGT---GQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLE 1392 A + GT Q P P + T +T+ V +P ++ R +E Sbjct: 8939 AVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITR-----IE 8993 Query: 1393 VAAAPSVTP-QAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 + + ++TP T+ + S P + + T ++T MSS++ P P S Sbjct: 8994 MESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIE--DSMTQVMSSSRGPSPDQS 9051 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPR 1511 + ST + + S+S I T + T+T T PG + L S Sbjct: 9052 TMSQDIST--EVITRLSTSPIKTESTE------MTITTQTGSPGATSRGTLTLDTS---- 9099 Query: 1512 QQLPPRQLLQSASTALMGESAEVLSA--SQTPELPAAVDLSSTGEPSSGQESAGSAVVAT 1569 + + STA G S ++A S+TP D+ PS + S+ S +++ Sbjct: 9100 ----TTFMSGTHSTASQGFSHSQMTALMSRTPG-----DVPWLSHPSVEEASSASFSLSS 9150 Query: 1570 VVVQPPPPTQS----EVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQA 1624 V+ P S + SLP L+ TT L+ T PE + + +A+ Sbjct: 9151 PVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAEI 9210 Query: 1625 AATEE 1629 A E Sbjct: 9211 LAITE 9215 Score = 86.3 bits (212), Expect = 3e-16 Identities = 267/1350 (19%), Positives = 481/1350 (35%), Gaps = 197/1350 (14%) Query: 397 LQKYDIPATAATATSPT-PNPVPSVPANPPKSP---APAAAAPAVQPLTQVGITLLPQAA 452 ++K P++ + ++ T P+P+ S P+ S + P + T + T L Sbjct: 8847 VEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVT 8906 Query: 453 PAPPT-----------------TTTIQVLPTVPGSSISVPTAART-----QGVPAVLKVT 490 +PP+ T IQ+ + + +A + G+P KVT Sbjct: 8907 TSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVT 8966 Query: 491 GPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALA 550 P T+ T + T++PA + + T+ + + S + Sbjct: 8967 SPVVTSSTI------------KDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIH 9014 Query: 551 AAAAATQKIPPSSAP--TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATR 608 +A PS+ P + S ++ + M+ + G + +T+ S +++ +T Sbjct: 9015 SATK------PSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTS 9068 Query: 609 MLKTAAA------QVGTSVSSATNTSTRPIITVHKSGTVTVAQQA---QVVTTVVGGVTK 659 +KT + Q G+ +++ T T T SGT + A Q +T ++ Sbjct: 9069 PIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPG 9128 Query: 660 TITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTG-QASTGPVTQIIQTKGPLPA 718 + + P SA S VM+ + PV ++ +S+ PVT ++ T G + Sbjct: 9129 DVPWLSHPSVEEASSASFSLSSPVMT--SSSPVSSTLPDSIHSSSLPVTSLL-TSGLVKT 9185 Query: 719 GTILKLV-------------TSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGT 765 +L TSA+ T +TT T G + SPS+ + Sbjct: 9186 TELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADS 9245 Query: 766 TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVM--------------TSGTGAP 811 T T M +TS+P I T + TS Sbjct: 9246 VTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEK 9305 Query: 812 AKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMG-GVRLVTPVTVSAVKPAVT 870 + ++++VP AT + T+ + PG T+ + +T ++ + T Sbjct: 9306 STVLSSVPTGATTEVSR--TEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKEST 9363 Query: 871 TLVVK---GTTGVTTLGTVTGTVSTSLAGAGGHSTSASL--ATPITTLGTIATLSSQVIN 925 + + G +G T+ GT T S++ + G HS + + +TT + + Sbjct: 9364 DMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPS 9423 Query: 926 PTAITVSAAQTTLTAAGGLTTP-----TITMQPVSQPTQVTLITAPSGVEAQPVHDLPVS 980 P ++ ++ ++L ++ +T+P T + S P VT + ++A + D + Sbjct: 9424 PLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLD---A 9480 Query: 981 ILASPTTEQPTATVTIADS-GQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGG 1039 L TT P +T +S T + +H T +AT + ++ G Sbjct: 9481 SLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVE--TTSATEELYSSSPG 9538 Query: 1040 HPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRV----CSNPPCETHETGTTNTATTAT 1095 +PT+V + + ST + + R+ S+ ET T+ T++T Sbjct: 9539 FSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSST 9598 Query: 1096 SNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGA 1155 + P T E T ++ +S+ PA +S+ Sbjct: 9599 ETSTVLY--KMPSGATPEVSRTEVMPSSRTSIPG--------------PAQSTMSLDISD 9642 Query: 1156 LEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSP-----AFVQ 1210 + S S T T TT T + PL G SM G S + + Sbjct: 9643 EVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPL-GTSMTFLSGTHSTMSQGLSHSE 9701 Query: 1211 LAPLSSK--VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPST 1268 + L S+ LS S + + R S ++++ +T S ++PV +L SPS+ Sbjct: 9702 MTNLMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTS--------LSPVSSTLLDSSPSS 9753 Query: 1269 TVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETG 1328 + VT +L+ P T + E + + N ++TS A + H + Sbjct: 9754 PLPVT---SLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSS 9810 Query: 1329 TTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVE 1388 T A TS+ E+H + + ++++ ++ + TV Sbjct: 9811 NTAVAKVRTSSS---------------VHESHSSVLADSETTITIPSMGITSAVDDTTVF 9855 Query: 1389 SGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHET-----GTTHTATT---VTSNM 1440 + + P T L P + S ET G +ATT +T M Sbjct: 9856 TSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIM 9915 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT--TVTQSTPVPGPSV 1498 SSN+ P SDQ ST + + IT SS++ T T+T PG + Sbjct: 9916 SSNRIHIP-DSDQ----STMSPDI---ITEVITRLSSSSMMSESTQMTITTQKSSPGATA 9967 Query: 1499 PPPEELQVSPGP----RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGE 1554 L + P +PPR L S T LM S E P +++ + T Sbjct: 9968 QSTLTLATTTAPLARTHSTVPPR-FLHSEMTTLMSRSPE------NPSWKSSLFVEKTSS 10020 Query: 1555 PSS--GQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPE-- 1610 SS S V++ + Q P + V L P + T+T T L+P Sbjct: 10021 SSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKT---TDTSTEPGTSLSPNLS 10077 Query: 1611 --ELAVTAAAEAAAQAAATEEAQALAIQAV 1638 + + AA+E + ++A+ V Sbjct: 10078 GTSVEILAASEVTTDTEKIHPSSSMAVTNV 10107 Score = 85.9 bits (211), Expect = 4e-16 Identities = 278/1361 (20%), Positives = 487/1361 (35%), Gaps = 151/1361 (11%) Query: 457 TTTTIQVLPTVPGSSIS--VPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPV 514 T TT + P + +SIS + ++ T VP ++TG ATT + +S Sbjct: 4887 TETTSSLTPKLRETSISQEITSSTETSTVP-YKELTG--ATTEVSRTDVTSSSSTSFPGP 4943 Query: 515 TVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKI----PPSSAPTVLSV 570 +++ + T+ + ++ S +++ A +Q P ++ P Sbjct: 4944 DQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIH 5003 Query: 571 PAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT---NT 627 A T + VT + +P V S P + + ++ A S+ S+T + Sbjct: 5004 SAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDK 5063 Query: 628 STRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS-VPGGSALISNLGKVMSV 686 + P+ ++ SG V + ++ T + VT ++ S + S + ++ Sbjct: 5064 LSSPMTSLLTSGLVKITD---ILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPS 5120 Query: 687 VQTKPVQTSAV-TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT-----TTQ 740 + T+ A +G S P +T P T ++T+ G P + +++ Sbjct: 5121 INTEETNVKANNSGHESHSPALADSET----PKATTQMVITTTVGDPAPSTSMPVHGSSE 5176 Query: 741 ASGAGTKPTI-----LGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSP 795 + +PT L +S S ++ P T+ + + + IT+ +TGV SS I +P Sbjct: 5177 TTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTP 5236 Query: 796 ITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVR 855 +T + TG ++ T+ I T + +T + +P P Sbjct: 5237 DHDKSTVPPDTFTGEIPRVFTS--SIKTKSAEMTIT---TQASP----------PESASH 5281 Query: 856 LVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGT 915 P+ S TTL GT T G V T+L G G + S P+ + Sbjct: 5282 STLPLDTS------TTLSQGGTHSTVTQGFPYSEV-TTLMGMGPGNVSWMTTPPVEETSS 5334 Query: 916 IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVH 975 +++L S + VS+ + L + + T V T+P V + P + Sbjct: 5335 VSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPN 5394 Query: 976 DLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVA 1035 L+S T E+P T D+ E +TNTA T V Sbjct: 5395 ------LSSITHERP---ATYKDTAH----------------TEAAMHHSTNTAVTNVGT 5429 Query: 1036 NLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTAT 1095 + GH + V + D + + A+ + ST + V + +T++ T TA + Sbjct: 5430 SGSGHKSQSSV--LADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTA--SL 5485 Query: 1096 SNMAGQHGCSNPPCETHETGT--TNTATTAMSSVGANHQRDARRACAAGTPAVIRISVAT 1153 S + S T ET T + T A++ +R + + I ++T Sbjct: 5486 SPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDLDRPTIAPDIST 5545 Query: 1154 GALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPL-LGPSMAREPGGRSPAFVQLA 1212 G + S ++ + + T+ T T AT S G L S GG Q Sbjct: 5546 GMITRLFTSPIMTKSAEMTVTTQTTTPGAT----SQGILPWDTSTTLFQGGTHSTVSQGF 5601 Query: 1213 PLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTV 1272 P S L S + D+ + + V + S + +PV + PS+ + V Sbjct: 5602 PHSEITTLRSRTPGDV-SWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPV 5660 Query: 1273 TALEALLCPSATVTQVCSNPPCETHETGTTN----TATTSNAGSAQRVCSNPPCETHETG 1328 TA L S VT T+ GTT+ T++ N S + +T T Sbjct: 5661 TA----LLTSVLVT--------TTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTE 5708 Query: 1329 TTHTAT-TATSNGGTGQPEGGQQPPAGRPCETHQTTST---GTTMSVSVGALLPDATSSH 1384 H + T T+ G G + + P ++H + +T G T ++ ++ +TS+ Sbjct: 5709 AMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTSV---STSTP 5765 Query: 1385 RTVESGLEVAAAPSVTP-QAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSN 1443 E+ ++ + S+ P T T S E T TT + T S Sbjct: 5766 AFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRT 5825 Query: 1444 QDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST------LTRAVTTVTQSTPVPGPS 1497 P S ST+ IT S ST T + T++Q+T S Sbjct: 5826 TISGPDHSKMSPYISTE----TITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTS 5881 Query: 1498 VPPPEELQVSPGPRQQLPPRQLLQSASTALMGES-------AEVLSASQTPELPAAVDLS 1550 E SP Q+ P + + S + G S E S S LPA S Sbjct: 5882 STASWEGTHSP-VTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHS 5940 Query: 1551 STGEPSSGQESAGSAVVATVVVQ------PPPPTQSEVDQLSLP-------QELMAEAQA 1597 S SG + V +++ T SE+ SLP + L +EA Sbjct: 5941 SLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEAST 6000 Query: 1598 GTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQA---LAIQAVLQAAQQAVMGTGEPMD 1654 T T+ + T E T + ++ + +Q + + A++ T P Sbjct: 6001 NTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTP-- 6058 Query: 1655 TSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQE-LAALVQQQQLQEAQAQQQHHHLP 1713 S V + L+ E +E + T+ + + V E + ++ P Sbjct: 6059 GSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDP 6118 Query: 1714 TEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATES 1754 T A A S P I + + + P T++ + AT++ Sbjct: 6119 TFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQT 6159 Score = 79.7 bits (195), Expect = 3e-14 Identities = 156/665 (23%), Positives = 251/665 (37%), Gaps = 82/665 (12%) Query: 377 TNSLEVSWGAVATADSYLLQLQKYDIP--ATAATATSPTPNPVPSVPANPPKSPAPAAAA 434 T S+ S GA AT+D + + D+P T+ +S T + ++P S P Sbjct: 11376 TPSIATSPGAEATSDFPTITVSP-DVPDMVTSQVTSSGTDTSI-TIPTLTLSSGEPETTT 11433 Query: 435 PAV---QPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP--AVLKV 489 + + T I LP + A T++ V+ + S+ + PT T P +++ Sbjct: 11434 SFITYSETHTSSAIPTLPVSPGASKMLTSL-VISSGTDSTTTFPTLTETPYEPETTAIQL 11492 Query: 490 TGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAAL 549 P A T T + P K+ T+LP + P S+ + SP MS + Sbjct: 11493 IHP-AETNTMVPRTTPKFSHSKSD---TTLPVAITSPGPEASSAVSTTTISPDMSDLVTS 11548 Query: 550 AAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPG--TTTLPATVKVAS------SPVM 601 ++ T ++ PT+ P T P +TT+ T+ S +P M Sbjct: 11549 LVPSSGTDT--STTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSM 11606 Query: 602 VSNPA--------TRMLKTAAAQVGTS--VSSATNTSTR-PIITVHKSGTVTVAQQAQVV 650 V++P T + + V TS SSAT+TST P +T T A A Sbjct: 11607 VTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHP 11666 Query: 651 TTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG-----P 705 T G T+ + P S P M+ T P QTS + ++ P Sbjct: 11667 GTQTGF---TVPIRTVPSSEPD----------TMASWVTHPPQTSTPVSRTTSSFSHSSP 11713 Query: 706 VTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGT 765 + P + L T + G P + + +SGA T T+ +++ S P T Sbjct: 11714 DATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTV---PTLTHSPGMPET 11770 Query: 766 TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGH 825 T ++ T P + T T P TT +T GA TA+P T Sbjct: 11771 TALLSTHPRTE-------TSKTFPASTVFPQVSETTASLTIRPGAETS--TALPTQTTSS 11821 Query: 826 G----QQGVTQVVLKGAPGQPGTILRTVPMG---GVRLVTPVTVSAVKPAV---TTLVVK 875 G ++V L PG +T P+ G T + S + + T L+ Sbjct: 11822 LFTLLVTGTSRVDLSPT-ASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLAT 11880 Query: 876 GTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQ 935 ++ T+ T+T TVS +++G S + +T+ T + S + P + + Sbjct: 11881 SSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTG 11940 Query: 936 TTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATV- 994 TT+T PT + T I + VEA + + +SPT + T T Sbjct: 11941 TTMTLIPS-EMPTPPKTSHGEGVSPTTILRTTMVEATNL----ATTGSSPTVAKTTTTFN 11995 Query: 995 TIADS 999 T+A S Sbjct: 11996 TLAGS 12000 Score = 79.3 bits (194), Expect = 3e-14 Identities = 261/1285 (20%), Positives = 454/1285 (35%), Gaps = 191/1285 (14%) Query: 473 SVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSA 532 S+P+ V + L + P T+ + T+ + + PVT V+ +++ Sbjct: 8551 SLPSVEEASSVSSSL--SSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTS 8608 Query: 533 QGTVIGSSPQMSGMAALAAAAAAT----QKIPPSSAPTVLSVPAGTTIVKTMA------- 581 S P +S +A A + +KI PSS V++V GT I K ++ Sbjct: 8609 SEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNV--GTVIYKHLSPSSVLAD 8666 Query: 582 --VTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSG 639 T T+ + T + ++ V S PA + T +S+ + R I T ++ Sbjct: 8667 LVTTKPTSPMATTSTLGNTSVSTSTPAF------PETMMTQPTSSLTSGLREISTSQETS 8720 Query: 640 TVTV--AQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAV 697 + T A + + T V++T L S PG + S + +S + T Sbjct: 8721 SATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQ--STISPEISTETITRISTPLT 8778 Query: 698 TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQAS--GAGTKPTILGISS 755 T ++ +T G GT +S P T T S T P G Sbjct: 8779 TTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPED 8838 Query: 756 VSPSTTKPGTTTIIKTIPMSAIITQAGATGVT-----------SSP----GIKSPITIIT 800 VS P ++ KT P S++++ + T + SSP + +P+ + T Sbjct: 8839 VS----WPSRPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKT 8894 Query: 801 TKVMTSG-----TGAPAKIITAVPKIATGHGQQGVTQVVLKG--APGQPGTILRTVPMGG 853 T ++ + T P+ IT+ +AT + L A Q GTI Sbjct: 8895 TDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYS 8954 Query: 854 VRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTL 913 P P VT+ +K T S+ + STS TP T Sbjct: 8955 SYPGLPEPSKVTSPVVTSSTIKDIVSTTI------PASSEITRIEMESTSTLTPTPRETS 9008 Query: 914 GTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQP 973 +SQ I+ + LT+A + T M P+ T + + Sbjct: 9009 ------TSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSP-DQSTMSQDISTEV 9061 Query: 974 VHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTV 1033 + L S + + +TE T+T G GT+TL +T TT + T Sbjct: 9062 ITRLSTSPIKTESTEM---TITTQTGSPGATSRGTLTL----------DTSTTFMSGTHS 9108 Query: 1034 VANLG-GHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTAT 1092 A+ G H Q T A S V + V S+ T+++ Sbjct: 9109 TASQGFSHSQMT----------ALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSSSP 9158 Query: 1093 TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVA 1152 +++ H S P +G T T + + + + ++ + ++ I+ Sbjct: 9159 VSSTLPDSIHSSSLPVTSLLTSGLVKT--TELLGTSSEPETSSPPNLSSTSAEILAITEV 9216 Query: 1153 TGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLA 1212 T E + + + S+ + T S+ + P+ +PAF + Sbjct: 9217 TTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTS 9276 Query: 1213 PLSSKVRLS-SPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCE-------SLQGG 1264 + +K +LS +P + + + + + + SSV G E S+ G Sbjct: 9277 RIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGP 9336 Query: 1265 SPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCET 1324 + ST + T++E + S +T+ S T +TG + ++Q + T Sbjct: 9337 AQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGA-------TSQGTFTLDSSST 9389 Query: 1325 HETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSH 1384 TH+ATT P+ P R E S + +SV + P + S Sbjct: 9390 ASWPGTHSATTQRF------PQSVVTTPMSRGPED---VSWPSPLSVEKNSP-PSSLVSS 9439 Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 +V S + + PS G++ +P P + TS M Sbjct: 9440 SSVTSPSPLYSTPS-----GSSHSSPVPV-------------------TSLFTSIMMKAT 9475 Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 D A+ E E+T ++NITS ++ + ++T T A+ + + EEL Sbjct: 9476 DMLDASL---EPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEEL 9532 Query: 1505 -QVSPG---PRQQLPPRQLLQS-----ASTALMGESA----EVLS-ASQTP---ELPAAV 1547 SPG P + + P S ST + G S E+ S +S TP E + Sbjct: 9533 YSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQ 9592 Query: 1548 DLSSTGEPSS---GQESAGSAVVATVVVQP------PPPTQSEVDQLSLPQELMAEAQAG 1598 D++S+ E S+ S + V+ V P P P QS + L + E++ Sbjct: 9593 DITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTM-SLDISDEVV------ 9645 Query: 1599 TTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEA 1658 T L + + E +T + A ++ L + + M G Sbjct: 9646 -TRLSTSPIMTESAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQG-------- 9696 Query: 1659 AATVTQAELGHLSAEGQEGQATTIP 1683 ++ +E+ +L + G E + T P Sbjct: 9697 ---LSHSEMTNLMSRGPESLSWTSP 9718 Score = 79.0 bits (193), Expect = 5e-14 Identities = 279/1337 (20%), Positives = 476/1337 (35%), Gaps = 213/1337 (15%) Query: 406 AATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTT------ 459 A S T +P + ++ PA+A+P+ LT+V L Q + TT Sbjct: 1554 AQDTLSATMSPTHVTQSLKDQTSIPASASPS--HLTEVYPELGTQGRSSSEATTFWKPST 1611 Query: 460 ------------TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPAS 507 IQ P + ++ ++ T G+ + T A T T + R +S Sbjct: 1612 DTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSS 1671 Query: 508 -----QAGKAPVTVTSLPAG--------VRMVVPTQSAQGTVI---GSSPQMS--GMAAL 549 AG + VTS P V V+ + +G GSSP+++ G AL Sbjct: 1672 TATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTAL 1731 Query: 550 AAA--------AAATQKIPPSSAPTVLSVP-AGTTIVKTMAVTPGTTTLPATVKVASSPV 600 +++ + + IP +S+PT V G + T VT T+ Sbjct: 1732 SSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTS------------ 1779 Query: 601 MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT 660 +S + R ++A + T++ S NT + T S + + VT + + Sbjct: 1780 DISKSSARTESSSATLMSTALGSTENTGKEKLRTA--SMDLPSPTPSMEVTPWI-----S 1832 Query: 661 ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720 +TL +P + +L + G V T T A +TG G + Sbjct: 1833 LTLSNAPNTT---DSLDLSHG-----VHTSSAGTLATDRSLNTGVTRASRLENGSDTSSK 1884 Query: 721 ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI-IT 779 L + S T + +S +P + + T+ PG I T+P S+I + Sbjct: 1885 SLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVE 1944 Query: 780 QAGATGVTSSPGIKS------PITIITTKVMTSGT----GAPAKIITAVPKIATGHGQQG 829 + +TG+TS P I S PIT T ++GT P +++ Sbjct: 1945 EVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPY 2004 Query: 830 VTQVVLKGAPGQPGTILR----TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGT 885 V V + +P ++ + P L + + + + A+T+ + TT + T Sbjct: 2005 VNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTW 2064 Query: 886 VTGTVSTSLA-GAGGHSTSASLATPITTLGTIATLSSQVINPTAITV----SAAQTTLTA 940 + ++S +L+ G G S +S T +T +++ NP T +AA T T Sbjct: 2065 PSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTD 2124 Query: 941 AGGLTTPTIT------MQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATV 994 A +T + T V P +T + SG+ ++ + + +S T+ T T+ Sbjct: 2125 ASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKL-TRTI 2183 Query: 995 TIADSG-----QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 ++ S + + P TV++ + P TTNT T+ V + G T V Sbjct: 2184 SLPTSESLVSFRMNKDPWTVSIPLGSHP-------TTNTETSIPVNSAGPPGLSTVASDV 2236 Query: 1050 CDR-QEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPP 1108 D + A S+ T + + V S+ P +T T + T ++ T + + + P Sbjct: 2237 IDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKT--THSFRTISSLTHELTSR--VTPIP 2292 Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168 + + + T A S+ +R A +P V+ S + S Sbjct: 2293 GDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFT-------ETSTVSLDN 2345 Query: 1169 RQTSATSTTMTVMATGA----PCSAGPLLGPSMAREPGG-RSPAFVQLAPLSSKVRLSSP 1223 T TS + T S+ L+ S+A A + +S SSP Sbjct: 2346 ETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSP 2405 Query: 1224 SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGS-----PSTTVTVTALEAL 1278 S+ S T + A P ++ SL GGS PST T + Sbjct: 2406 SLFS------SDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPV 2459 Query: 1279 LCPSATVTQVCSNPPCETHETG-TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTA- 1336 SA + + P T T +T+TA+ N S+ V ++ P T T Sbjct: 2460 ETSSALLAW---SRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPA 2516 Query: 1337 -----TSNGG--------TGQPEGGQQPPAGRPCETHQT-TSTGTTMSVSVGALLPDATS 1382 TS G T +P P T + TS + ++ S + + Sbjct: 2517 MGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQ 2576 Query: 1383 SHRTVESGL--EVAAAPS----VTPQAGTALLAPFPTQ-----RVCSNPPCETHETGTTH 1431 + T SG E +A P VT + T L + S PP + TGT Sbjct: 2577 TPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLS 2636 Query: 1432 ----------------TATTVTSNMSSNQDPPP----AASDQGEVESTQGDSVNITSSSA 1471 TAT TS+++++ D P A+ G V T ++ A Sbjct: 2637 GASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDA 2696 Query: 1472 ITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQ------------LPP--- 1516 + S R++ +T P P PR LP Sbjct: 2697 LVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTT 2756 Query: 1517 ------RQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQ-ESAGSAVVAT 1569 + S +TAL+ SA + AS P + ++S+G SG S G+ ++ Sbjct: 2757 GSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSS 2816 Query: 1570 VVVQPPPPTQSEVDQLS 1586 + + P + + +++ Sbjct: 2817 LPLTMNPGEVTAMSEIT 2833 Score = 78.2 bits (191), Expect = 8e-14 Identities = 275/1299 (21%), Positives = 463/1299 (35%), Gaps = 215/1299 (16%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGI--TLLPQAAPAPPTTTT 460 P T+ A T + +P +P K+ A ++ + +G+ + LP++ T + Sbjct: 41 PKTSTGAIVVTEHTLPFT--SPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSE 98 Query: 461 IQVLPTVPGSSISVPTAARTQGVPAVLKVTG---PQATTGTPLVTMRPASQAGKAPVTVT 517 + P++ P+ + PA V+G P+ T + + V T Sbjct: 99 QRTSPSLSPQVNGTPS----RNYPATSMVSGLSSPRTRTSSTEGNFTKEASTYTLTVETT 154 Query: 518 SLPAGVRMVVPTQSAQGTVIGSSPQM------------SGMAALAAAAAATQKIPPSSAP 565 S P + VPT+++ T G S + S M A + A+ + P S P Sbjct: 155 SGPVTEKYTVPTETS--TTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTP 212 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625 +V T +T P TL ++ S ++ L+ + G SS Sbjct: 213 AETTVTDSHTPGRT---NPSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGYPFSSPE 269 Query: 626 NTS---TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS--VPGGSALISNL 680 S +R + S + +V T++ G + T SP+S VP A Sbjct: 270 PGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLT-----SPLSPGVPEARASTMPN 324 Query: 681 GKVMSVVQTKPVQTSAVTGQASTGPV-TQIIQTKGPLPAGTILKLVTSADGK--PTTIIT 737 + + +TSA +++ + T I TK A TIL A+ P+T I Sbjct: 325 SAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQT--AETILTFHAFAETMDIPSTHIA 382 Query: 738 TTQAS-GAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGV---------T 787 T AS G+ T+ G S+ + +TT P TT + + + G T Sbjct: 383 KTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLET 442 Query: 788 SSPGIKSPI--TIITT---KVMTSGTGAPAKIITAVP---------------KIATGHGQ 827 S+PG +S + T++ T + S +P+++ ++ P HG Sbjct: 443 SAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGS 502 Query: 828 QGVTQVVLKGAP--------------GQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLV 873 + + +P ++ P ++V +TT V Sbjct: 503 SDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSV 562 Query: 874 VKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSA 933 +G TTL T +S G TSA +T G + Q PT I+++ Sbjct: 563 PSVVSGFTTLKT------SSTKGIWLEETSADTLIGESTAG---PTTHQFAVPTGISMTG 613 Query: 934 AQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTAT 993 +T + G TT +T S T L A +GV PVS+ SP + A Sbjct: 614 GSSTRGSQG--TTHLLTRATASSETSADLTLATNGV--------PVSV--SPAVSKTAA- 660 Query: 994 VTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQ 1053 S G +P + T+V S P ET + ++ +LG P T+ F Sbjct: 661 ---GSSPPGGTKP-SYTMVSSVIP----ETSSLQSSAFREGTSLGLTPLNTRHPFSSPEP 712 Query: 1054 EAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHE 1113 ++A ST S+ + S +ATS + S+ T E Sbjct: 713 DSAGHTKIST------SIPLLSS--------ASVLEDKVSATSTFSHHKATSSITTGTPE 758 Query: 1114 TGT-TNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTS 1172 T T ++ +SS+ ++ AA +P R+ AT L S + Sbjct: 759 ISTKTKPSSAVLSSMTLSN--------AATSPE--RVRNATSPLTHPSPSGEE------- 801 Query: 1173 ATSTTMTVMATGAPCSAGPLLGPS-MAREPGGRSPAFVQLAPLS---SKVRLSSPSIKDL 1228 T+ ++ ++T A + P + P+ SP+ + L +S + S+PS Sbjct: 802 -TAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLF 860 Query: 1229 PAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQV 1288 +G + S ++++ R S+ T T A S V+++ Sbjct: 861 TSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSEL 920 Query: 1289 CSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATT-------ATSNGG 1341 T++T+ T++ GSA P +H TGT + T + + Sbjct: 921 ----------RATSSTSVTNSTGSAL------PKISHLTGTATMSQTNRDTFNDSAAPQS 964 Query: 1342 TGQPEGGQQPPAGRPCETHQTTSTGTTMS--VSVGALLPDATSSHR--------TVESGL 1391 T PE + G P T +++ T++S V V ATSS T Sbjct: 965 TTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTT 1024 Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH-ETGTTHTATT----------VTSNM 1440 E P A T + P + +H GTT ++ T V+ ++ Sbjct: 1025 ETTNGPGSMAVASTNI--PIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSV 1082 Query: 1441 SSNQDPPPAASD----QGEVESTQGDSVNITSSSAITTT---VSSTLTRAVTTVTQSTPV 1493 S +Q A S + T D V +S IT SS LT +T +P Sbjct: 1083 SPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPD 1142 Query: 1494 PGPS----VPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDL 1549 PG + + SP P+ + Q +T+++ ++ E S P LP+ L Sbjct: 1143 PGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVET-SRWNMPNLPSTTSL 1201 Query: 1550 SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP 1588 + + P+SG + V P P T E + LP Sbjct: 1202 TPSNIPTSGAIGKSTLVPLDT---PSPATSLEASEGGLP 1237 Score = 76.3 bits (186), Expect = 3e-13 Identities = 322/1623 (19%), Positives = 560/1623 (34%), Gaps = 335/1623 (20%) Query: 435 PAVQPLTQVGITLLPQA--APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP 492 P V+ + V + A +P+P ++T+ Q +P+ P ++PT+ VL T P Sbjct: 5327 PPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTD-VLGTTSP 5385 Query: 493 QATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAA 552 ++ T +P +S + P T + + + T +G+S + A Sbjct: 5386 ESVTSSP---PNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLA 5442 Query: 553 AAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKT 612 + T K P + T +T+ T +V+ T + T ++ + P +P R Sbjct: 5443 DSETSKATPLMSTT-------STLGDT-SVSTSTPNISQTNQIQTEPTASLSPRLR---- 5490 Query: 613 AAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPG 672 + TS +++ T T + +G +T A + ++ ++ T L + I+ Sbjct: 5491 ---ESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSR----TSISDLDRPTIAPDI 5543 Query: 673 GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLV------T 726 + +I+ L T P+ T + +T T ++G LP T L T Sbjct: 5544 STGMITRLF-------TSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHST 5596 Query: 727 SADGKPTTIITTTQASGAG---------TKPTILGISSVSPSTTKPG--TTTIIKTIPMS 775 + G P + ITT ++ G + T G S +SPS T P ++T ++IP S Sbjct: 5597 VSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSS 5656 Query: 776 ----------AIITQAGATGVTSS-------PGIKSP----ITIITTKVMTSGTGAPAKI 814 ++T G TS P + SP +T T A Sbjct: 5657 PLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHT 5716 Query: 815 ITAVPKIAT---GHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAV-- 869 TAV + T GH Q P T T PMG + +VS PA Sbjct: 5717 NTAVANVGTSISGHESQS-------SVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFE 5769 Query: 870 -------TTLVVKGTTGVTT---LGTVTGTVS-----------------------TSLAG 896 T+ ++ G T + TVT T + T+++G Sbjct: 5770 TRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISG 5829 Query: 897 AGGHSTSASLATP-ITTLGTIATLSSQ----VINPTAITVSAAQTTLT-------AAGGL 944 S ++T IT L T ++ + N T + +Q TLT + G Sbjct: 5830 PDHSKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGT 5889 Query: 945 TTPTITMQPVSQPTQVTLITAPSGVEAQ----------PVHDLPVSIL------------ 982 +P P S+ T T+ + GV Q P +P+ + Sbjct: 5890 HSPVTQRFPHSEET-TTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSG 5948 Query: 983 ASPTTEQP-TATVTIADSGQGDVQPGTVTLVCSNPPCETHETG---TTNTATTTVVANLG 1038 +SPT+ P T+ +T D+ LV S+ P + +G T+ +T T + Sbjct: 5949 SSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFS 6008 Query: 1039 GHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNM 1098 + T + + +S+ S Q +G + E T+ + T N+ Sbjct: 6009 ENTAETNMGTTNSMHKLHSSV--SIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNV 6066 Query: 1099 AGQHGCSNPPCETHETGT------TNTATTAMSSVGANHQRDARRA-CAAGTPAVIRISV 1151 P E E T T + T SSV + + RA P + S Sbjct: 6067 DRDSTSPLTP-ELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASA 6125 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGP---------SMAREPG 1202 + S + T +T +AT S LG + A P Sbjct: 6126 QSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPS 6185 Query: 1203 GRSPAFVQLAPLSSKVRLSSPSIKDLP-AGRHSHAVSTAAMTRSSVGAGEPRMAPVCESL 1261 R+ FV S + +K P + ++++S+ A + +PV +L Sbjct: 6186 ARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSP-----SPVTSTL 6240 Query: 1262 QGGSPSTTVTVTALE----ALLCPSATVTQVCSNPPCETHETGTTNTATTS--------N 1309 Q S S+ V+VT++ A + T + + P T T+ ATT N Sbjct: 6241 QEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSIN 6300 Query: 1310 AGSAQRVCSNPPCETHET------------GTTHTATTATSNGGTGQPEGGQQPPAG--- 1354 A ++ P E + T T+T+ S T P Sbjct: 6301 TAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESET 6360 Query: 1355 --------RPCETHQ----TTSTGTTMSVSVGALLPDA-----TSSHRTVESGLEVAAAP 1397 R T Q ++ T T + A + TSS RT G E P Sbjct: 6361 TFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTE---KP 6417 Query: 1398 SVTPQAGTALLAPFPT--------QRVCSNP--PCETHETGTTHTATTVTSNMSSNQDPP 1447 +++P T + T +R + P GT T++T++ + Sbjct: 6418 TMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAM 6477 Query: 1448 P---AASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504 + D + S + ++ TS ++ T SS+ ++ +T +PVP PE Sbjct: 6478 THGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVP---TTLPESR 6534 Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAA---------------VDL 1549 SP LP L+++ S S + ++P + + Sbjct: 6535 PSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAV 6594 Query: 1550 SSTGEPSSGQESAGSAV-----------------VATVVVQPPPPTQSEVDQLSLPQEL- 1591 ++ G +S +ES S + +V P SE+ ++ + Sbjct: 6595 TNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFS 6654 Query: 1592 MAEAQAGTTTLMVTGLTPEELAV-----TAAAEAAAQAAA-------------------- 1626 +A GT+T ++ E+ AV T A E + A Sbjct: 6655 LAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDIS 6714 Query: 1627 TEEAQALAIQ-AVLQAAQQAVMG-TGEPM-DTSEAAATV----TQAELGHLSAEGQEGQA 1679 TE +L I + +++ ++ TG P+ TS+ T+ T + G S QE Sbjct: 6715 TEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPH 6774 Query: 1680 TTIPIVLTQQ-ELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAG 1738 + + V+ + E+ + +++ + +L P+ ++ P + S Sbjct: 6775 SEMTTVMNKDPEILSWTIPPSIEKTSF--------SSSLMPSPAMTSPPVSS-------- 6818 Query: 1739 TVPSTVALLPSTATESLAPSNTF------VAPQPVVVASPAKLQAAA----TLTEVANGI 1788 T+P T+ PS T L PS +P+P +SP L + + T E I Sbjct: 6819 TLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEP-TTSSPPNLSSTSHEILTTDEDTTAI 6877 Query: 1789 ESL 1791 E++ Sbjct: 6878 EAM 6880 Score = 75.5 bits (184), Expect = 5e-13 Identities = 340/1628 (20%), Positives = 552/1628 (33%), Gaps = 261/1628 (16%) Query: 395 LQLQKYDIPATAATATSPTPNPVPSVPAN-----------PPKSPAPAAAAPAVQPL--- 440 +Q +P +T+ +P+ VP + P +P ++ L Sbjct: 3680 VQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWD 3739 Query: 441 TQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPL 500 T ++ AP TT Q L + IS T+ + + P A + Sbjct: 3740 TGRSLSSATATTSAPQGATTPQELTLE--TMISPATSQLPFSIGHITSAVTPAAMARSSG 3797 Query: 501 VTM-RPASQAGKAPVTVTSLPAGVRM---VVPTQSAQGTVIGSSP----------QMSGM 546 VT RP + KA T T LP VP +A T + P Q G Sbjct: 3798 VTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAA--TTLDVIPHTAKTPDATFQRQGQ 3855 Query: 547 AALAAAAAAT-------QKIPPS-----------SAPTVLSVPAGTTIVKTMAVTPGTTT 588 AL A AT +K PS S T+ V + +++++T+ T Sbjct: 3856 TALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTL----NTLD 3911 Query: 589 LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT-STRPIITV--HKSGTVTVAQ 645 + SSP S+P R+ + + ++ +TNT T +T H S + A Sbjct: 3912 INLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAH 3971 Query: 646 QAQ------VVTT-----VVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPV-Q 693 A VVTT + ++ T + S L L V + T Q Sbjct: 3972 SASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQ 4031 Query: 694 TSAVTGQAST----GPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPT 749 TS ++ ST GP T+I +K + + + + + S+D P+ IT A T+ Sbjct: 4032 TSIISSPGSTAITKGPRTEITSSKR-ISSSFLAQSMRSSDS-PSEAITRLSNFPAMTES- 4088 Query: 750 ILGISSVSPSTTKPGTTTI-IKTIPMSAIITQAGATGVTSSPGIKSPITIITTK------ 802 G ++ T+ PG T++ T+ SA + G T+ S T + +K Sbjct: 4089 --GGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTS 4146 Query: 803 ---------VMTSGTGAPAKIITAVPKI---ATGHGQQG---VTQVVLKGAPGQPGTILR 847 +S + P T+ I + GH VT V L G + + Sbjct: 4147 QPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSG----LGK 4202 Query: 848 TVPMGGVRL-----VTPVTVSAVKPAVTTLVVKGTT-----GVTTLGTVTGTVSTSLAGA 897 T M + L + P S A++T T T T S+ + Sbjct: 4203 TTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPI 4262 Query: 898 GGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQP 957 GH+ + +P+ T + ++S + + +T + GL + + S Sbjct: 4263 PGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSAT 4322 Query: 958 TQVTLIT-APSGVEAQPVHDLPVSILASPTTEQP----TATVTIADSGQGDVQPGTVTLV 1012 T+IT SG V + + + P T+T T D P T ++ Sbjct: 4323 ETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVS---TNPSTSLIM 4379 Query: 1013 C-SNPPCETHETGTTNTAT-------TTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTV 1064 S+ T +TG T AT T+ + L P F+ + S V Sbjct: 4380 TESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDV 4439 Query: 1065 GQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAM 1124 + V S P T TT ATS + GQH S+P T + TT M Sbjct: 4440 SWTSPPSVAETSYPSSLTPFLVTT--IPPATSTLQGQH-TSSPVSATSVLTSGLVKTTDM 4496 Query: 1125 SSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATG 1184 + ++ + + ++ AT +E S ++ T +A+S V+ + Sbjct: 4497 LNTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAH--VLHST 4554 Query: 1185 APCSAGPLLGPSMAREPGGRSPAFVQLA-PLSSKVRLSSPSIKDLPAGRHSHAV--STAA 1241 P S+ P S A ++ P S + L AGR ++ + Sbjct: 4555 LPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNS 4614 Query: 1242 MTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCS----NPPCETH 1297 T S++ + + E+ + PS T A + V S N P T Sbjct: 4615 TTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTI 4674 Query: 1298 ETGTTNTATTSNAGSAQRVCSNPPCETHET----------GTTHTATTATSNGGT---GQ 1344 T T T T S+ G+ ++ T ET G H+ T N Q Sbjct: 4675 STHMTTTQTGSS-GATSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQ 4733 Query: 1345 PEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPD--ATSSHRTVESGLE---VAAAPSV 1399 Q A P + Q TT+ SV A P +TSS ++ S L V A V Sbjct: 4734 TNPPFQDEASSP--SSQAPVLVTTLPSSV-AFTPQWHSTSSPVSMSSVLTSSLVKTAGKV 4790 Query: 1400 TPQAGTALLAPFPTQRVCSN---PPCETHETGTTHTA-TTVTSNMSSNQDPPPAASDQGE 1455 T +P + T + TTH + TV +N+ + + S Sbjct: 4791 DTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSA 4850 Query: 1456 V-ESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS------- 1507 E ++ S N+T+S+ TT+S ++ ++ T T P E +S Sbjct: 4851 YPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSST 4910 Query: 1508 ------------------------------PGPRQQLPPRQLLQSASTAL-----MGESA 1532 PGP Q + +T L M ESA Sbjct: 4911 ETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESA 4970 Query: 1533 EVLSASQTPELPAAVDLSSTGEPSSGQESAG---------SAVVATVVVQPPPPTQS--- 1580 E+ +QT A + T +PS+ AG S + T ++ P S Sbjct: 4971 EITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTS 5030 Query: 1581 --EVDQLSLPQELMAEAQAGTTTLMVTGLTPEELA------VTAAAEAAAQAAATEEAQA 1632 VD+ S P ++ T +L+ + L ++L+ +T+ T Sbjct: 5031 PPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPV 5090 Query: 1633 LAIQAVLQAAQQAVMGTG-EPMDTSEAAATVTQAEL-------GHLS-----AEGQEGQA 1679 + + ++ T + DT E ++ E GH S A+ + +A Sbjct: 5091 TSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKA 5150 Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNE---L 1736 TT ++ T A + + PT L P + ES+ + L Sbjct: 5151 TTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFL 5210 Query: 1737 AGTVPS-TVALLPSTAT------------ESLAPSNTFVAPQPVVVASPAKLQAA-ATLT 1782 VP+ T+ + ST +S P +TF P V S K ++A T+T Sbjct: 5211 LSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTIT 5270 Query: 1783 EVANGIES 1790 A+ ES Sbjct: 5271 TQASPPES 5278 Score = 75.1 bits (183), Expect = 7e-13 Identities = 300/1534 (19%), Positives = 517/1534 (33%), Gaps = 301/1534 (19%) Query: 404 ATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQV 463 ++A++ TSP+ + ++ AN S + AP L+Q ++PA + + Sbjct: 3483 SSASSVTSPSIG-LETLRANV--SAVKSDIAPTAGHLSQT-------SSPAEVSILDVTT 3532 Query: 464 LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQ----AGKAPVTVTSL 519 PT PG S ++ T + T P G + PA++ + + P T +S Sbjct: 3533 APT-PGISTTITTMGTNS-----ISTTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSST 3586 Query: 520 PAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQ---KIPPSSAPTVLSVPAGTTI 576 A V ++ V S +S M + A++T+ P TV+ T Sbjct: 3587 AASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPS 3646 Query: 577 VKTMAVTPGTTTLPATVK----VASSPVMVSNPATRML--------------KTAAAQVG 618 AV T+T T+ AS+P+ + RM T A V Sbjct: 3647 SDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVP 3706 Query: 619 TSVSSATNTSTR-----PIITVHKSGTVTV-------AQQAQVVTTVVGGVTKTITLVKS 666 S+ S + ST+ P+ T T+ A T+ G T L Sbjct: 3707 VSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLE 3766 Query: 667 PISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVT 726 + P S L ++G + S V + S+ + P ++ Sbjct: 3767 TMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSK------------------ 3808 Query: 727 SADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGV 786 A+ T + TTT A + V P T K T + +A+ T+A AT Sbjct: 3809 KAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQ-GQTALTTEARATSD 3867 Query: 787 TSSPGIKS-PITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTI 845 + + KS P T++M S + K +T+ ++ Sbjct: 3868 SWNEKEKSTPSAPWITEMMNSVSEDTIKEVTS------------------------SSSV 3903 Query: 846 LRTVPMGGVRLVTPVTVSA---------VKPAVTTL----VVKGTTGVTTLGTVTGTVST 892 LRT+ + L + T S + P+ +T + T V T G VT + Sbjct: 3904 LRTLNTLDINLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHA 3963 Query: 893 SLAGAGGHSTSASLATPITTLGT-------------------------IATLSSQVINPT 927 S + HS S+ L +P+ T T T+ + ++P Sbjct: 3964 SHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPY 4023 Query: 928 AITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTT 987 T S QT++ ++ G T IT P ++ T I++ ++ D P S Sbjct: 4024 MDTSSTTQTSIISSPGST--AITKGPRTEITSSKRISSSFLAQSMRSSDSP-----SEAI 4076 Query: 988 EQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQ 1047 + + + +SG G + + ++PP T + + T T+ A+ G P T + Sbjct: 4077 TRLSNFPAMTESG------GMILAMQTSPPGAT--SLSAPTLDTSATASWTGTPLATTQR 4128 Query: 1048 FVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNT-----ATTATSNM---- 1098 F + S Q + P ET ++++ ATT+ SN+ Sbjct: 4129 FTYSEKTTLFSKGPEDTSQPS----------PPSVEETSSSSSLVPIHATTSPSNILLTS 4178 Query: 1099 AGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEA 1158 G S PP T+ + S +G +R + GT +S G + Sbjct: 4179 QGHSPSSTPP-------VTSVFLSETSGLGKTTDM-SRISLEPGTSLPPNLSSTAGEALS 4230 Query: 1159 AQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKV 1218 + + SA + + AT + S P+ PG P+ Sbjct: 4231 TYEASRDTKAIHHSADTAVTNMEATSSEYS--PI--------PGHTKPS----------- 4269 Query: 1219 RLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL 1278 + +SP + SH + + S G+ E S+ G + + A A Sbjct: 4270 KATSPLVT-------SHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSA- 4321 Query: 1279 LCPSATVTQVCSNPPCETHETGT--TNTATTSNAGSAQRVCSNPPCETHETGTTHTATTA 1336 ++TV S+ TH T T T ++ TS + Q + S T + + Sbjct: 4322 -TETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMT 4380 Query: 1337 TSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAA 1396 S+G T TT TG T + + G L D ++ E+ L A Sbjct: 4381 ESSGVT------------------ITTQTGPTGAATQGPYLLDTSTMPYLTETPL--AVT 4420 Query: 1397 PSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEV 1456 P T L++ P ++PP + + + + + PP ++ QG+ Sbjct: 4421 PDFMQSEKTTLISKGPKDVSWTSPPSVAETSYPSSLTPFLVTTI-----PPATSTLQGQH 4475 Query: 1457 ESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPP 1516 S+ + ++ +S + TT L ++ VT S P P E+ + + Sbjct: 4476 TSSPVSATSVLTSGLVKTT--DMLNTSMEPVTNS---PQNLNNPSNEILATLAATTDIET 4530 Query: 1517 RQLLQSASTALMG--ESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQP 1574 + + MG SA VL ++ LP + + S+ P S G A+ + + Sbjct: 4531 IHPSINKAVTNMGTASSAHVLHST----LPVSSEPSTATSPMVPASSMGDALASISI--- 4583 Query: 1575 PPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATE------ 1628 P D P + + +TL T E + + A AT+ Sbjct: 4584 --PGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSF 4641 Query: 1629 -------EAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATT 1681 AQ+ + A + + P T T TQ G G + Sbjct: 4642 DATFIPTPAQSTKFPDIFSVASSRL--SNSPPMTISTHMTTTQT--------GSSGATSK 4691 Query: 1682 IPIVLTQQEL-AALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDP-----AIESNCLNE 1735 IP+ L L + + E A + + N P + S+ Sbjct: 4692 IPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPV 4751 Query: 1736 LAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKP 1795 L T+PS+VA P + S PV ++S T +V +E++ Sbjct: 4752 LVTTLPSSVAFTPQWHSTS----------SPVSMSSVLTSSLVKTAGKVDTSLETV---- 4797 Query: 1796 DLPPPPSKAPMKKENQWFDVGVIKG--TNVMVTH 1827 + +P N D+ V T++ TH Sbjct: 4798 ------TSSPQSMSNTLDDISVTSAATTDIETTH 4825 Score = 70.5 bits (171), Expect = 2e-11 Identities = 274/1349 (20%), Positives = 468/1349 (34%), Gaps = 198/1349 (14%) Query: 559 IPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASS---PVMVSNPATRMLKTAAA 615 +P +++ T ++P I K+ V P T PAT AS P + + P + T + Sbjct: 1195 LPSTTSLTPSNIPTSGAIGKSTLV-PLDTPSPATSLEASEGGLPTLSTYPEST--NTPSI 1251 Query: 616 QVGTSVSSATNTSTR-PIITVHKSGTVTVAQQAQVVTTV-VGGVTKTITLVKSP-ISVPG 672 +G SS + ++ + + +V K G+ T + T + V + SP ++ PG Sbjct: 1252 HLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPG 1311 Query: 673 GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP 732 + S + T P TS+ Q ST + ++T + P Sbjct: 1312 ETNTGSTWDPTTYITTTDPKDTSSA--QVSTPHSVRTLRT---------------TENHP 1354 Query: 733 TTIITTTQASGAGTKPTILGISSVSPSTTKPGTT--TIIKTIPMSA------IITQAGAT 784 T T A K ISS SP+ T P T TI T S + ++ Sbjct: 1355 KTESATPAAYSGSPK-----ISS-SPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGF 1408 Query: 785 GVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGT 844 S+PG S + I T+ + S T + P + Q +T + Sbjct: 1409 ETQSAPGPVS-VVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTE 1467 Query: 845 ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSL---AGAGGHS 901 + + + +P++ A+ P ++T + + + T ST+L G Sbjct: 1468 EMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLG 1527 Query: 902 TSASLAT-PITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960 + L T PIT L T T +S + + T AQ TL+A +PT Q + T + Sbjct: 1528 RTGDLTTVPITPLTT--TWTSVIEHSTQ-----AQDTLSAT---MSPTHVTQSLKDQTSI 1577 Query: 961 TLITAPSGV-EAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCE 1019 +PS + E P + ++E T D+ +++ G T + S PP + Sbjct: 1578 PASASPSHLTEVYP----ELGTQGRSSSEATTFWKPSTDTLSREIETGP-TNIQSTPPMD 1632 Query: 1020 THETGTTNTATTTVVANL---GGHPQPTQVQFVCDRQEAAAS---------LVTSTVGQQ 1067 TG++++ T +A+L P T +R+ + A+ LVTS G+ Sbjct: 1633 NTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRS 1692 Query: 1068 NGSVVRVCSNPPCETHETGTTNTA--TTATSNMAGQHGCSNPPCETHETGTTNTATTAMS 1125 + S+ E+ G T+++ ++ N G S+ ++ G+ + + ++ Sbjct: 1693 ISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLT 1752 Query: 1126 SVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGA 1185 S + T V + + + +A+ S T+ ST T Sbjct: 1753 SSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLR 1812 Query: 1186 PCSAG-PLLGPSMAREPG-----GRSPAFVQLAPLSSKVRLSS----------------- 1222 S P PSM P +P LS V SS Sbjct: 1813 TASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNTGVTRA 1872 Query: 1223 --------PSIKDLPAGRHSHAVST---AAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 S K L G +H T + SS+ AP E+ +P Sbjct: 1873 SRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAI 1932 Query: 1272 VTALEALLCPSATV--TQVCSNPPCE----THETGT------TNTATTSNAGSAQRVCSN 1319 L P V T + S P TH T T+T T + S+ Sbjct: 1933 SLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSS 1992 Query: 1320 PPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS--------- 1370 T + + A S T + P + S +T+S Sbjct: 1993 EKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWL 2052 Query: 1371 ----VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHE 1426 S+ +TS + SG + PS T A + NP ETH Sbjct: 2053 WDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHG 2112 Query: 1427 TGTTHTAT--TVTSNMSSNQDPPPAASDQGEVE-----STQGDSVNITSSSAITTTVSST 1479 T +T T S+++ + P AS EV +++ D +TS S ++ T Sbjct: 2113 PQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSL-GT 2171 Query: 1480 LTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQ 1539 + A T +T++ S+P E L + L S T S V SA Sbjct: 2172 ASSAGTKLTRTI-----SLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGP 2226 Query: 1540 TPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT 1599 A D+ T PS G ES + TV P P T+ Sbjct: 2227 PGLSTVASDVIDT--PSDGAES-----IPTVSFSPSPDTE-------------------- 2259 Query: 1600 TTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTG-EPMDTSEA 1658 VT ++ T + + ++ I ++ + TG P T Sbjct: 2260 ----VTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGE 2315 Query: 1659 AATVTQAELGHLSAEGQEGQATTIPIVL----TQQELAALVQQQQLQEAQA--QQQHHHL 1712 T+T A TT PIVL T+ +L + ++ + ++ + L Sbjct: 2316 RRTITSA------------APTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNEL 2363 Query: 1713 PTEALAPADSLNDPAIESNC-LNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVAS 1771 P+++ + +D +N S + + A P++++ + ++++ SL S+ P + Sbjct: 2364 PSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETN 2423 Query: 1772 PAKLQAAATLTEVANGIESLGVKPDLPPP 1800 A + ++ T +G ++G P PP Sbjct: 2424 TATSPSVSSNTYSLDGGSNVGGTPSTLPP 2452 Score = 68.9 bits (167), Expect = 5e-11 Identities = 300/1441 (20%), Positives = 485/1441 (33%), Gaps = 236/1441 (16%) Query: 402 IPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTT--- 458 IP +A S PV S ++P K+ A AP + Q +T P+ T Sbjct: 2848 IPVKPTSAESGLLTPV-SASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSAS 2906 Query: 459 --TTIQVLPTVPGSSISVPTA-----------ARTQGVPAVLKVTGPQAT--TGTPLVTM 503 T Q L T+P S S ++ AR + + Q+T T TP + Sbjct: 2907 LPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSA 2966 Query: 504 RPASQAGKAPVTVTSLPAGVR-----MVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQK 558 P S AG P TS R M P S + + S+ S + L + A + Sbjct: 2967 SP-SMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARS 3025 Query: 559 IPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLK------- 611 SS+P LS T+ + A T T+L +A P ++ + T L Sbjct: 3026 -GSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTL 3084 Query: 612 ----------------------TAAAQVGTSVSSATNTSTRPIITVHK------------ 637 TA Q T S T TS P+ + + Sbjct: 3085 NMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETW 3144 Query: 638 SGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAV 697 + +++V + +V T G + TI + S + G S + + S P TS Sbjct: 3145 ASSISVPAKTSLVETTDGTLVTTIKM--SSQAAQGNSTWPAPAEETGS----SPAGTSPG 3198 Query: 698 TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP--TTIITTTQASGAGTKPTILGISS 755 + + ST +I+ +K P + I V ++ K TT+ T + T LG S Sbjct: 3199 SPEMST--TLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGS 3256 Query: 756 VSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKV-----MTSGTGA 810 S S GTT+ K+ + + T+ V+ SP T + + + T + Sbjct: 3257 TSISHLPTGTTSPTKSPTENMLATER----VSLSPSPPEAWTNLYSGTPGGTRQSLATMS 3312 Query: 811 PAKIITAVPKIATGHGQQGVTQVVLK-----------GAPGQPGTILRTVPMGGVRLVTP 859 + + + TG GQQ ++V K G G ++ L P Sbjct: 3313 SVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDP 3372 Query: 860 VTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT-------- 911 VT ++T T + + TV + A TS S+ + Sbjct: 3373 VTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQ 3432 Query: 912 TLGTIATL--SSQVINPTAITVSAAQTTLTA--AGGLTTPTITMQPVSQPTQVTLITAPS 967 T G+ TL S V N IT +A T+L + +G ++T + + + +T+PS Sbjct: 3433 TSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPS 3492 Query: 968 -GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTT 1026 G+E L ++ A + PTA S +V VT + T T T Sbjct: 3493 IGLET-----LRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGT 3547 Query: 1027 NTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG 1086 N+ +TT P P D A TST P T Sbjct: 3548 NSISTTT-------PNPEVGMSTMDSTPATERRTTST-------------EHPSTWSSTA 3587 Query: 1087 TTN--TATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTP 1144 ++ T T TSN+ + S T T + ++T + S+ H R + TP Sbjct: 3588 ASDSWTVTDMTSNL--KVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTP 3645 Query: 1145 AVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTV--MATGAPCSAGPLLGPSMAREPG 1202 + +V T ++ + S T ++ ST V M+ P PS + E Sbjct: 3646 SSDASAVKT-ETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPS-STEAE 3703 Query: 1203 GRSPAFVQLAPLSSKVRLSSP-------SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMA 1255 + V S+K ++P S+ L S A T + GA P+ Sbjct: 3704 DVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQEL 3763 Query: 1256 PVCESLQGGSPSTT--------VTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATT 1307 + + SP+T+ +T A + S+ VT +P + E +T TT Sbjct: 3764 TLETMI---SPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTT 3820 Query: 1308 SNAGSAQ-------------RVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAG 1354 ++A Q P G T T A + + + P A Sbjct: 3821 TSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSWNEKEKSTPSAP 3880 Query: 1355 RPCETHQTTSTGTTMSV-SVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPT 1413 E + S T V S ++L + +ESG + + +P A + T Sbjct: 3881 WITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSPYERIA-PSESTT 3939 Query: 1414 QRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVES----TQGDSVNITSS 1469 + +P T T T VTS+ ++ PA S ++ S T I S Sbjct: 3940 DKEAIHP-----STNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSM 3994 Query: 1470 SAIT--------TTVSSTLTRAVTTVT----QSTPVPGPSVPPPEELQVSPGPRQQL--- 1514 S T T +S LT + V+ S+ + P ++ GPR ++ Sbjct: 3995 STTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITSS 4054 Query: 1515 -----------------PPRQLLQSASTALMGESAEVLSASQT----------PELPAAV 1547 P + + ++ M ES ++ A QT P L + Sbjct: 4055 KRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSA 4114 Query: 1548 DLSSTGEPSSGQESAGSAVVATV-------VVQPPPPTQSEVDQLSLPQELMAEAQAGTT 1600 S TG P + + + T+ QP PP+ E S + A Sbjct: 4115 TASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNI 4174 Query: 1601 TLMVTGLTPEEL--AVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEA 1658 L G +P + + T + ++++ GE + T EA Sbjct: 4175 LLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEA 4234 Query: 1659 A 1659 + Sbjct: 4235 S 4235 Score = 66.2 bits (160), Expect = 3e-10 Identities = 86/396 (21%), Positives = 159/396 (40%), Gaps = 23/396 (5%) Query: 401 DIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTT 460 D A+ T T PV ++ S A A P T+ +L +P P T Sbjct: 11685 DTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVT 11744 Query: 461 IQVLPTVPGSSISVPTAARTQGVP--AVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTS 518 Q+ + +S +VPT + G+P L T P+ T Q + ++T Sbjct: 11745 SQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTI 11804 Query: 519 LP-AGVRMVVPTQSAQG--TVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT 575 P A +PTQ+ T++ + ++ A+ + + P S+ P + +T Sbjct: 11805 RPGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTET----ST 11860 Query: 576 IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIIT- 634 ++ T ++ G L T +A+S ++ +T L + A G S +S T + + + Sbjct: 11861 MIPTSTLSLG--LLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSW 11918 Query: 635 -VHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQ 693 S +VT + TV G T+TL+ S + P ++ + ++++T V+ Sbjct: 11919 NTETSPSVTSVGPPEFSRTVTG---TTMTLIPSEMPTPPKTSHGEGVSPT-TILRTTMVE 11974 Query: 694 TSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGI 753 + + S+ V + T L AG++ +T+ + T + + I Sbjct: 11975 ATNLATTGSSPTVAKTTTTFNTL-AGSLFTPLTTPGMSTLASESVTSRTSYNHRSWISTT 12033 Query: 754 SSV-----SPSTTKPGTTTIIKTIPMSAIITQAGAT 784 SS +P+T+ P T+T I S+I + AT Sbjct: 12034 SSYNRRYWTPATSTPVTSTFSPGISTSSIPSSTAAT 12069 Score = 47.0 bits (110), Expect = 2e-04 Identities = 173/885 (19%), Positives = 308/885 (34%), Gaps = 112/885 (12%) Query: 955 SQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCS 1014 S PT+ +L+T +A P D S L T T+T I V T+ Sbjct: 11 SSPTR-SLMTGSRSTKATPEMD---SGLTGATLSPKTSTGAIV------VTEHTLPFTSP 60 Query: 1015 NPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNG----- 1069 + + + T ++ P+ T Q + SL G + Sbjct: 61 DKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPAT 120 Query: 1070 SVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGA 1129 S+V S+P T T T +T + + S P E + T T T+TT S Sbjct: 121 SMVSGLSSPRTRTSSTEGNFTKEASTYTLTVET-TSGPVTEKY-TVPTETSTTEGDSTET 178 Query: 1130 NHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSA 1189 D R T + + +T + E A S + +T T + + T + G S+ Sbjct: 179 PW--DTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSS 236 Query: 1190 GPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGA 1249 L P P R ++L ++ SSP P +ST+A SS Sbjct: 237 FLDLSPKGT--PNSRGETSLELILSTTGYPFSSPE----PGSAGHSRISTSAPLSSSASV 290 Query: 1250 GEPRMAPVCESLQGGSPSTTVT---VTALEALLCPSATV--TQVCSNPPCETHETGTT-- 1302 + +++ S+ G T+ V A P++ + + SN +T Sbjct: 291 LDNKISET--SIFSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTIS 348 Query: 1303 --NTATTSNAGSAQRVCS-NPPCETHETGTTHTATTATSNG-GTGQPEGGQQPPAGRPCE 1358 T + S +A+ + + + ET + +TH A T S G+ GG Sbjct: 349 SLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGT--------- 399 Query: 1359 THQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCS 1418 +TS TT S S + + + H T E S+TP +A Sbjct: 400 ---STSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSA------------ 444 Query: 1419 NPPCETHETGT---THTATTVTSNMSS-----NQDPPPAASDQGEVESTQGDSVNITSSS 1470 P E+ T T T TT+ S + S + P G Q S SS Sbjct: 445 -PGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSS 503 Query: 1471 AITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQ------LLQSAS 1524 I +S+ ++A + ++ST + ++ SP + + PP + S Sbjct: 504 DILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVP 563 Query: 1525 TALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQ 1584 + + G + S+++ L + GE ++G + AV + + T+ Sbjct: 564 SVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGT 623 Query: 1585 LSLPQELMAEAQAGTTTLMVTGLTPEEL--AVTAAAEAAAQAAATEEAQALAIQAVLQAA 1642 L A ++ + T P + AV+ A ++ T+ + + + + + Sbjct: 624 THLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETS 683 Query: 1643 --QQAVMGTG-----EPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALV 1695 Q + G P++T ++ GH +T+IP++ + L V Sbjct: 684 SLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKI------STSIPLLSSASVLEDKV 737 Query: 1696 QQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPST-ATES 1754 + HH T ++ + P I + T PS+ L T + + Sbjct: 738 -------SATSTFSHHKATSSI----TTGTPEISTK-------TKPSSAVLSSMTLSNAA 779 Query: 1755 LAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPP 1799 +P A P+ SP+ + A ++ ++ E+ P++ P Sbjct: 780 TSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTD-SPNIHP 823 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 132 bits (331), Expect = 4e-30 Identities = 282/1307 (21%), Positives = 435/1307 (33%), Gaps = 225/1307 (17%) Query: 364 PPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPAN 423 P PP QL + +V W T+ + L P++ T SPT P+ +PA Sbjct: 1202 PQPPTTPQLPTTGSRPTQV-WPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPL--LPAT 1258 Query: 424 PPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGV 483 S A++ +P T V PQA P T T++ T P + + A + Sbjct: 1259 LTSSKPTASSGEPPRPTTAV----TPQATSGLPPTATLRSTATKPTVTQATTRATASTAS 1314 Query: 484 PAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQM 543 PA Q+TT T + PA+ +G +P +LP +P +A T G P Sbjct: 1315 PATTSTA--QSTTRTTMTLPTPAT-SGTSP----TLPKSTNQELPGTTATQTT-GPRPT- 1365 Query: 544 SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVS 603 A Q P+ + TT T TP TT P T A SPV + Sbjct: 1366 ---PASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPT---AGSPVPST 1419 Query: 604 NPATRMLKTAAAQVGTSVSSATNTSTR-----PIITVHKSGTVTVAQQAQVVTTVVGGVT 658 P T A T T T + + TV AQ+ T+ Sbjct: 1420 GPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSA----- 1474 Query: 659 KTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPA 718 S S P G+ P T TG T P P+ Sbjct: 1475 -------SNHSAPTGT--------------IPPPTTLKATGSTHTAP---------PI-- 1502 Query: 719 GTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKP-----GTTTIIKTIP 773 PTT T+ S T T + S + ST P TTTI Sbjct: 1503 ------------TPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPT 1550 Query: 774 MSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQV 833 + T T +S P T + +S + + K T + Sbjct: 1551 STRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTY-------- 1602 Query: 834 VLKGAPGQPGTILRT-VPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVST 892 P P T L T VP LVTP T + + P + + GT+ + Sbjct: 1603 ---PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTL 1659 Query: 893 SLAGAGGHSTSASLATPITTLGTIATLSS--QVINPTAITVSAAQTTLTAAGGLTTPTIT 950 G ST + +TT GT LSS T++ + T A +T IT Sbjct: 1660 KATG----STHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNIT 1715 Query: 951 MQPVSQPTQVTLITAPSGVEAQ----------PVHDLPVSILASPTTEQPTATVTIADSG 1000 P S T +T +++ +H S T T ++T + Sbjct: 1716 PNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTS 1775 Query: 1001 QGDVQPGTVT-----------LVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049 G P T +PP T +T T T +P P+ Sbjct: 1776 TGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTT 1835 Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPC 1109 S TS V +V+ TH T AT+A+ + + G PP Sbjct: 1836 LPTH--VPSFSTSLVTPSTHTVI-------IPTH----TQMATSASIH-SMPTGTIPPPT 1881 Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTR 1169 TG+T+TA + Q + + A + ++ + +T E S + + Sbjct: 1882 TIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPK 1941 Query: 1170 QTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLP 1229 TS + T T A S P P P S F P+++ S + P Sbjct: 1942 HTSTGTRTPVAHTTSASSSRLPT--PFTTHSPPTGSSPFSSTGPMTA---TSFQTTTTYP 1996 Query: 1230 AGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVC 1289 H + P SL +PST + + SA++ Sbjct: 1997 TPSHPQTTLPT------------HVPPFSTSLV--TPSTHTVIITTHTQMATSASIHSTP 2042 Query: 1290 SN---PPCETHETGTTNTA---TTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTG 1343 + PP TG+T+TA T + +G++Q TH + +T TA+++ + + Sbjct: 2043 TGTVPPPTTLKATGSTHTAPPMTVTTSGTSQ---------THSSFSTATASSSFISSSSW 2093 Query: 1344 QPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQA 1403 P+ P P T LP +S+ V + +++++ S +P A Sbjct: 2094 LPQNSSSRPPSSPITTQ----------------LPHLSSATTPVSTTNQLSSSFSPSPSA 2137 Query: 1404 GTALLAPFPTQRVCSNPPCETHETGTT--------HTATTVTSNMSSNQDPPPAASDQGE 1455 + + + P+ S+P + GT+ H+ T + + SS P AS Sbjct: 2138 PSTVSSYVPSSH--SSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA- 2194 Query: 1456 VESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLP 1515 S SS A +TT+ +TL + S+P ++ P + VSP P L Sbjct: 2195 -------SPLFPSSPAASTTIRATLPHTI-----SSPFTLSALLPISTVTVSPTPSSHLA 2242 Query: 1516 ------PRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVAT 1569 P +AST + + S++ L V S +SG ++ V Sbjct: 2243 SSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTN 2302 Query: 1570 VVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTA 1616 + + P PT S + T++L G TP V++ Sbjct: 2303 LTTRHPGPTLSPTTRFL------------TSSLTAHGSTPASAPVSS 2337 Score = 105 bits (261), Expect = 6e-22 Identities = 265/1171 (22%), Positives = 407/1171 (34%), Gaps = 191/1171 (16%) Query: 559 IPPSSA--PTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQ 616 +PP++ PT +P TT + V P T T T+ + SS + P+ T A+ Sbjct: 1197 MPPTTPQPPTTPQLP--TTGSRPTQVWPMTGT-STTIGLLSS----TGPSPSSNHTPASP 1249 Query: 617 VGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSAL 676 T + AT TS++P + + T A Q + G+ T TL + A Sbjct: 1250 TQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATS----GLPPTATLRSTATKPTVTQAT 1305 Query: 677 ISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736 S T Q++ T P T T LP T +L P T Sbjct: 1306 TRATASTASPATTSTAQSTTRTTMTLPTPATS--GTSPTLPKSTNQEL-------PGT-- 1354 Query: 737 TTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPI 796 T TQ +G P S+ P+T +PG T P + TQ T ++P ++P Sbjct: 1355 TATQTTGPRPTPA----STTGPTTPQPGQPTR----PTATETTQTRTTTEYTTP--QTPH 1404 Query: 797 TIITTKVMTSGTGAPAK-IITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRT-VPMGGV 854 T T T+G+ P+ +TA AT P P T L T VP Sbjct: 1405 T--THSPPTAGSPVPSTGPVTATSFHAT----------TTYPTPSHPETTLPTHVPPFST 1452 Query: 855 RLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLG 914 LVTP T + + P + + GT+ T+L G T+ + TP TT G Sbjct: 1453 SLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPP--TTLKATGSTHTAPPI-TP-TTSG 1508 Query: 915 TIATLSSQVIN--PTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQ 972 T SS N PT++ + T +T TIT P S T+ Sbjct: 1509 TSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRT------------ 1556 Query: 973 PVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTT 1032 PV+ S T+ +P T G S+P T T+ TTT Sbjct: 1557 -----PVAHTNSATSSRPPPPFTTHSPPTG-----------SSPFSSTGPMTATSFKTTT 1600 Query: 1033 VVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTAT 1092 HPQ T V + SLVT P T T T Sbjct: 1601 TYPT-PSHPQTTLPTHV---PPFSTSLVT----------------PSTHTVITPTHAQMA 1640 Query: 1093 TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVA 1152 T+ S + G PP TG+T+TA T + Q + A + ++ + + Sbjct: 1641 TSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSS 1700 Query: 1153 TGALEAAQGSKSQCQTRQTSATSTTMTVMATG----------APCSAGPLLGPSMAREPG 1202 T EA S + TS + MTV +G A S S P Sbjct: 1701 THHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPE 1760 Query: 1203 GRSPAFVQLAPLSSKVRLSSP-------SIKDLPAGRHSHAVSTAAMTRSSVG------- 1248 S + + P + +P + LP +H+ T SS G Sbjct: 1761 VTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSF 1820 Query: 1249 -------------AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSN---P 1292 P P S +PST + + SA++ + + P Sbjct: 1821 QTTTTYPTPSHPHTTLPTHVP-SFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPP 1879 Query: 1293 PCETHETGTTNTA---TTSNAGSAQRVCSNPPCET-----HETGTTH---TATTATSNGG 1341 P TG+T+TA T + +G++Q S +T + T +TH T+T+N Sbjct: 1880 PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNIT 1939 Query: 1342 TGQPEGGQQPPAGR-----------PCETHQT-------TSTGTTMSVSVGALLPDATSS 1383 G + P P TH +STG + S T S Sbjct: 1940 PKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPS 1999 Query: 1384 H--RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMS 1441 H T+ + + + VTP T ++ ++ ++ + TGT TT+ + S Sbjct: 2000 HPQTTLPTHVPPFSTSLVTPSTHTVIITTH--TQMATSASIHSTPTGTVPPPTTLKATGS 2057 Query: 1442 SNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV-----SSTLTRAVTTVTQSTPVPGP 1496 ++ PP + G ++ S SSS I+++ SS+ + TQ + Sbjct: 2058 THTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSA 2117 Query: 1497 SVPPPEELQV----SPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSST 1552 + P Q+ SP P + S+ ++ S V ++S P S+ Sbjct: 2118 TTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSS 2177 Query: 1553 GEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMA----EAQAGTTTLMVTGLT 1608 G SS +A V+ + P P S + +LP + + A +T+ V+ Sbjct: 2178 GSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTP 2237 Query: 1609 PEELAVTAAA--EAAAQAAATEEAQALAIQA 1637 LA + A A+T A A + Q+ Sbjct: 2238 SSHLASSTIAFPSTPRTTASTHTAPAFSSQS 2268 Score = 97.1 bits (240), Expect = 2e-19 Identities = 227/996 (22%), Positives = 344/996 (34%), Gaps = 149/996 (14%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGIT-------------LLP 449 P TA + + T P PS P + P + V P T IT P Sbjct: 1421 PVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAP 1480 Query: 450 QAAPAPPTT--------TTIQVLPTVPGSSISVPTAARTQGVPAVL-----KVTGPQAT- 495 PPTT T + PT G+S ++ T P L P+ T Sbjct: 1481 TGTIPPPTTLKATGSTHTAPPITPTTSGTS-QAHSSFSTNKTPTSLHSHTSSTHHPEVTP 1539 Query: 496 TGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAA 555 T T +T P S + PV T+ R P + GSSP S A + Sbjct: 1540 TSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPF-TTHSPPTGSSPFSSTGPMTATSFKT 1598 Query: 556 TQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTL--PATVKVASSPVMVSNPATRMLKTA 613 T P S P ++P T VTP T T+ P ++A+S + S P T Sbjct: 1599 TTTYPTPSHPQT-TLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMP------TG 1651 Query: 614 AAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVG-------------GVTKT 660 T++ + +T T P +T+ SGT T T T Sbjct: 1652 TIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTST 1711 Query: 661 ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720 + +P S ++ G T ++S T + ST + T P T Sbjct: 1712 TNITPNPTSTGTPPMTVTTSG-------TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTST 1764 Query: 721 ILKLVT---SADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI 777 +T ++ G T + TT A+ + PT ++ SP T GTT I T P++A Sbjct: 1765 STTSITPNHTSTGTRTPVAHTTSATSSRL-PT--PFTTHSPPT---GTTPISSTGPVTAT 1818 Query: 778 ITQAGATGVTSS----------PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGH-- 825 Q T T S P + + +T + T ++ + TG Sbjct: 1819 SFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIP 1878 Query: 826 -----GQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPV---TVSAVKPAVTTLVVKGT 877 G T P GT + T + T S P VT T Sbjct: 1879 PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPT---ST 1935 Query: 878 TGVTTLGTVTGTVSTSLAGAGGHSTSAS---LATPITTLGTIATLSSQVINPTAITVSAA 934 T +T T TGT T +A H+TSAS L TP TT T SS + +T ++ Sbjct: 1936 TNITPKHTSTGT-RTPVA----HTTSASSSRLPTPFTTHSP-PTGSSPFSSTGPMTATSF 1989 Query: 935 QTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHD---LPVSILASPTTEQPT 991 QTT T + P T+ P +L+T + H SI ++PT P Sbjct: 1990 QTTTTYPTP-SHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPP 2048 Query: 992 ATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQ------PTQ 1045 T A P TVT ++ +TH + +T TA+++ +++ PQ P+ Sbjct: 2049 PTTLKATGSTHTAPPMTVT---TSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSS 2105 Query: 1046 VQFVCDRQEAAASLVTSTVGQQNGS--------------VVRVCSNPPCETHETGTTNTA 1091 ++A+ ST Q + S V S+P + GT+++ Sbjct: 2106 PITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSF 2165 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAM-SSVGANHQRDARRACAAGTPAVIRIS 1150 +A + S+ TH T + +A+ SS A+ A +P + Sbjct: 2166 VSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSAL 2225 Query: 1151 VATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPA--F 1208 + + + S + + ST T +T + S + R P F Sbjct: 2226 LPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF 2285 Query: 1209 VQLA------PLSSKVRLS--------SPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRM 1254 V L P S L+ SP+ + L + +H + A+ SS+G P Sbjct: 2286 VSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345 Query: 1255 APVC------ESLQGGSPSTTVTVTALEALLCPSAT 1284 VC E + VTVT E +A+ Sbjct: 2346 PGVCSVREQQEEITFKGCMANVTVTRCEGACISAAS 2381 Score = 49.7 bits (117), Expect = 3e-05 Identities = 78/322 (24%), Positives = 113/322 (35%), Gaps = 47/322 (14%) Query: 1317 CSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSV--- 1373 CS HE G T T QP Q P T TGT+ ++ + Sbjct: 1180 CSQDEYFDHEEGVCVPCMPPT----TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSS 1235 Query: 1374 ----------------GALLP-DATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRV 1416 LLP TSS T SG +VTPQA T+ L P T R Sbjct: 1236 TGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQA-TSGLPPTATLRS 1294 Query: 1417 CSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV 1476 + P T T T TA+T + P ++ Q +T TS ++ T Sbjct: 1295 TATKPTVTQAT-TRATASTAS--------PATTSTAQSTTRTTMTLPTPATSGTSPTLPK 1345 Query: 1477 SSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLS 1536 S+ TT TQ+T GP P + GP P + +A+ + + Sbjct: 1346 STNQELPGTTATQTT---GPRPTPAS----TTGPTTPQPGQPTRPTATETTQTRTTTEYT 1398 Query: 1537 ASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQ 1596 QTP + + + PS+G +A S T P P + +LP + + Sbjct: 1399 TPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHP------ETTLPTHVPPFST 1452 Query: 1597 AGTTTLMVTGLTPEELAVTAAA 1618 + T T +TP + +A Sbjct: 1453 SLVTPSTHTVITPTHAQMATSA 1474 Score = 38.5 bits (88), Expect = 0.068 Identities = 68/277 (24%), Positives = 87/277 (31%), Gaps = 40/277 (14%) Query: 1536 SASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEA 1595 S +QTP LPA + SS SSG+ PP PT + Q + Sbjct: 1248 SPTQTPLLPATLT-SSKPTASSGE--------------PPRPTTAVTPQAT-------SG 1285 Query: 1596 QAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGE--PM 1653 T TL T P T A A+ + AT + + A GT P Sbjct: 1286 LPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPK 1345 Query: 1654 DTSE--AAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHH- 1710 T++ T TQ + G T P T+ Q + E Q H Sbjct: 1346 STNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHT 1405 Query: 1711 -HLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAP--SNTFVAPQPV 1767 H P A +P S S T P T + P S + V P Sbjct: 1406 THSPPTAGSPVPSTGPVTATS-----FHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTH 1460 Query: 1768 VVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKA 1804 V +P Q A T +N G P PP KA Sbjct: 1461 TVITPTHAQMA---TSASNHSAPTGTIP--PPTTLKA 1492 Score = 32.7 bits (73), Expect = 3.7 Identities = 44/185 (23%), Positives = 68/185 (36%), Gaps = 27/185 (14%) Query: 1741 PSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPP 1800 P+ LLP+T T S +++ P+P +P QA + L A + S KP + Sbjct: 1249 PTQTPLLPATLTSSKPTASSGEPPRPTTAVTP---QATSGLPPTAT-LRSTATKPTVTQA 1304 Query: 1801 PSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGT 1860 ++A + T +T +P+ GT P + QEL PGT Sbjct: 1305 TTRATASTASPATTSTAQSTTRTTMT---------LPTPATSGTSPTLPKSTNQEL-PGT 1354 Query: 1861 AYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISK--------SPDGAHLTWEP 1912 A R + + T PG P P A + ++ +P H T P Sbjct: 1355 -----TATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSP 1409 Query: 1913 PSVTS 1917 P+ S Sbjct: 1410 PTAGS 1414 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 129 bits (323), Expect = 4e-29 Identities = 305/1450 (21%), Positives = 504/1450 (34%), Gaps = 191/1450 (13%) Query: 400 YDIPATAATATSPTPNPVPSVPANPPKSPA-PAAAAPAVQPLTQVGITLLPQAAP---AP 455 Y P + T SP V S + P + V P + L ++ + Sbjct: 2331 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2390 Query: 456 PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMR-------PASQ 508 P +T V P P +S+ PA T + T +T PAS Sbjct: 2391 PGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 2450 Query: 509 AGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSS----- 563 P T+T+ G S+ T SP S + L + ++ P S+ Sbjct: 2451 QTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTL 2510 Query: 564 --APTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSV 621 +PT S+ +T T +P T PAT S+ + T+ +Q G++ Sbjct: 2511 PGSPTTPSLSEKSTTFYTSPRSPDATLSPATT--------TSSGVSEESSTSHSQPGSTH 2562 Query: 622 SSATNTST------RPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISV----- 670 ++A ST R T H S T TT G ++ T SP S Sbjct: 2563 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALS 2622 Query: 671 PGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADG 730 PG + +S G+ + + P T ST + G + A T V S+ G Sbjct: 2623 PGSTTALS-FGQESTTFHSSPGSTHTTLFPDST-------TSSGIVEAST---RVHSSTG 2671 Query: 731 KPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSP 790 P T T + + T P + G S+ T P +T + P +A +T SP Sbjct: 2672 SPRT----TLSPASSTSPGLQGESTTFQ--THPASTHTTPSPPSTATAPVEESTTYHRSP 2725 Query: 791 GIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVP 850 G T T PA T+ GH ++ + +P GT + Sbjct: 2726 G------------STPTTHFPASSTTS------GHSEKST---IFHSSPDASGTTPSSAH 2764 Query: 851 MGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPI 910 T S + T+ + G+T +TTL T T S A +S+ S T + Sbjct: 2765 S---------TTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL 2815 Query: 911 TT-------LGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV--- 960 + +G +T S T TVS A TT +T + P S T V Sbjct: 2816 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPR 2875 Query: 961 TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADS-----GQGDVQ---PGTVTLV 1012 + T+ G E H P S + TE T + +S Q P T+T Sbjct: 2876 STTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTA 2935 Query: 1013 -----CSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQ-FVCDRQEAAASLVTSTVGQ 1066 + P + TGTT + + + L G P+++ + S T ++ + Sbjct: 2936 DLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 2995 Query: 1067 QNGSVVRVCSNP-----PCETHETGTTNTATTATSNMAGQH-----------GCSNPPCE 1110 ++ + +P P T +G + ++T+ S H G S P Sbjct: 2996 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA 3055 Query: 1111 THETGTTNTAT-----TAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAA---QGS 1162 +H + + AT T SS+G T + ++ +G +EA+ S Sbjct: 3056 SHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS 3115 Query: 1163 KSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSS 1222 T T A+ST+ + + P + PG + A V+++ S+ Sbjct: 3116 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPG-TTAAPVEVSTTYHSRPSST 3174 Query: 1223 PSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV--CESLQGGSPSTT-VTVTALEALL 1279 P+ + + SS GA + P S+ G P+T+ ++ + E Sbjct: 3175 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA 3234 Query: 1280 CPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHET-GTTHTATTATS 1338 P +T T S + + + T S A + S +H G+THT Sbjct: 3235 LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP-- 3292 Query: 1339 NGGTGQPEGGQQPPAGR--PCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAA 1396 G T P Q+ A P T T S G+T + S+G P++T+ H S E Sbjct: 3293 -GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG---PESTTFHSGPGS-TETTLL 3347 Query: 1397 PSVTPQAG-----TALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451 P T +G T + + + +P T G + T + ++ + PP S Sbjct: 3348 PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 3407 Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAV-TTVTQSTPVPGPSVPPPEELQVSPGP 1510 E+ +T S + T ++ + + S+TL R+ +T S+PV + P P Sbjct: 3408 AFVELSTTSHGSPSSTPTTHFSAS-STTLGRSEESTTVHSSPVATATTPSP--------- 3457 Query: 1511 RQQLPPRQLLQSASTALMGESAEVLS---ASQTPELPAAVDLSSTGEPSSGQESAGSAVV 1567 +S ++ L+ ES S ++QT P + S GE S+ S+ + + Sbjct: 3458 ---------ARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTI 3508 Query: 1568 ATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAAT 1627 ++ P T + V++ + + TT + T + A+ ++ A T Sbjct: 3509 SSA----PSTTSALVEEPTSYHS--SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT 3562 Query: 1628 EEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSA---EGQEGQATTIPI 1684 A + +VL + M+T+ + T L S ATT+ Sbjct: 3563 IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLS- 3621 Query: 1685 VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTV 1744 A + E T A DS P + + + + Sbjct: 3622 -------PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 3674 Query: 1745 ALLPSTATES 1754 LLP++ T S Sbjct: 3675 TLLPASTTTS 3684 Score = 124 bits (311), Expect = 9e-28 Identities = 310/1337 (23%), Positives = 470/1337 (35%), Gaps = 250/1337 (18%) Query: 405 TAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVL 464 +++T P S P++ SPAP+ A V ++ ++P+ TT Sbjct: 409 SSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAF-----VKLSTTYHSSPSSTPTTHFSAS 463 Query: 465 PTVPGSSI------SVPTAARTQGVPAVLKVTG--------------------PQATTGT 498 T G S S P A T PA +G P+++T T Sbjct: 464 STTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST-T 522 Query: 499 PLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQ------SAQGTVIGSSPQMSGMAALAAA 552 + A+ G T +S P+ + T S + T S +SG + + A Sbjct: 523 SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKA 582 Query: 553 ------AAATQKIPPSSAPTVL-----SVPAGTTIVKTMAVTPGTTTLPATVKVA----S 597 A AT +P S P+VL P + ++T A+ PG+TT P + + S Sbjct: 583 SHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL-PGSTTKPGLSEKSTTFYS 641 Query: 598 SPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP--IITVHKSGTVTVAQQAQVVTTVVG 655 SP +P T L + G S S T+ S RP T G+ T+ +Q T Sbjct: 642 SP---RSPDTTHLPASMTSSGVSEESTTSHS-RPGSTHTTAFPGSTTMPGLSQESTASHS 697 Query: 656 GVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGP 715 T T + SP GS S+LG + ++P T +T + +++ P Sbjct: 698 SPGPTDTTL-SP-----GSTTASSLGPEYTTFHSRPGSTETTLLPDNT-TASGLLEASMP 750 Query: 716 L------------PAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKP 763 + PAG+ T+ G+ TT + + P + V PSTT Sbjct: 751 VHSSTRSPHTTLSPAGS-----TTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH 805 Query: 764 GTTTIIKTIPMSAIITQAG----ATGVTSSPGIKSPITIITTKVMTSGTG---------- 809 G+ + I T +SA T +G +T SSPG + + TSG G Sbjct: 806 GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT-TSGRGEESTTSHSST 864 Query: 810 ------APAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVS 863 AP+ V + + H G T P T R+ T + Sbjct: 865 THTISSAPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSGRSEESTASHSSQDATGT 922 Query: 864 AVKPAVTT---LVVKGTTGVTTLGTVTGTV---STSLAGAGGHSTS--ASLATPITTLGT 915 V PA +T L+ + TT + G++ T ST+ G ST+ +S +P TTL Sbjct: 923 IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSP 982 Query: 916 IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVH 975 +T SS V + + S +T T A P T P T ++P + Sbjct: 983 ASTTSSGVSEESTTSRSRPGSTHTTA----FPDSTTTPGLSRHSTTSHSSPGSTDTTL-- 1036 Query: 976 DLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVA 1035 LP S S +++ T + + + S + PG+ T + T + +T TT Sbjct: 1037 -LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL--- 1092 Query: 1036 NLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTAT 1095 P T + + A++ V S+ G ++ S P E+ T +T Sbjct: 1093 ----FPDSTTSSGIVE----ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 1144 Query: 1096 SNMAGQHGCSNPPCETHET-----GTTNTATTAMSSVGANHQRDA----RRACAAGTPAV 1146 + P E T G+T T SS + H + A+GT Sbjct: 1145 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 1204 Query: 1147 IRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPG-GRS 1205 S +G + + T + S ST +T + P PG + Sbjct: 1205 SAHSTTSG--------RGESTTSRISPGSTEITTL-------------PGSTTTPGLSEA 1243 Query: 1206 PAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGS 1265 +P S LS S+ L G S +RS G+ ++P + G S Sbjct: 1244 STTFYSSPRSPTTTLSPASMTSLGVGEES------TTSRSQPGSTHSTVSPASTTTPGLS 1297 Query: 1266 PSTTVTVT----ALEALLCPSATVTQV-------CSNPPCETHETGTTNTATTSNAGSAQ 1314 +T + + E + P +T T V + P TH T T +TTS Sbjct: 1298 EESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES 1357 Query: 1315 RVCSNPPCETHETGTTHTATTA----------TSNGGTGQP-----------EGGQQPPA 1353 P T +TG T TTA +S+G TG G P Sbjct: 1358 TAFPGSPAST-QTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR 1416 Query: 1354 GRPCETHQTTSTG--TTMSVS-------VGALLPDATSSHRTVESGLEVAAAPSVTPQAG 1404 P T TT G TT S+S PDAT S T S + + Q G Sbjct: 1417 LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG 1476 Query: 1405 TALLAPFP---TQRVCSNPPCETHET-GTTHTATTVTSNMSSN--QDPPPAASDQGEVES 1458 + FP T S P +H + G+T + S +S+ Q S G+ E+ Sbjct: 1477 STHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTET 1536 Query: 1459 TQGDSVNITSS--SAITTTVSS------TLTRAVTT----------------VTQSTPVP 1494 T ITS A T T SS TLT A +T + +TP P Sbjct: 1537 TLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 1596 Query: 1495 GPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSS--- 1551 + P E+ + R P ++ST L G S E + +P + Sbjct: 1597 PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL-GRSEESTTVHSSPGATGTALFPTRSA 1655 Query: 1552 ----TGEPSSGQESAGS 1564 GEP++ S+GS Sbjct: 1656 TSVLVGEPTTSPISSGS 1672 Score = 119 bits (297), Expect = 4e-26 Identities = 315/1542 (20%), Positives = 542/1542 (35%), Gaps = 206/1542 (13%) Query: 405 TAATATSPTPNPVPSVPANPPKSPAPAAAAPAV-QPLTQVGITLLPQAAPAPPTTTT--I 461 T A+ PV S +P + +PA + + T PAPPTTT+ + Sbjct: 3351 TTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV 3410 Query: 462 QVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521 ++ T GS S PT + + T L ++ +PV + P+ Sbjct: 3411 ELSTTSHGSPSSTPTTHFS--------------ASSTTLGRSEESTTVHSSPVATATTPS 3456 Query: 522 GVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVL---SVPAGTTIVK 578 R + T SSP + T P S + S + ++ Sbjct: 3457 PARSTTSGLVEESTTYHSSP----------GSTQTMHFPESDTTSGRGEESTTSHSSTTH 3506 Query: 579 TMAVTPGTTT--LPATVKVASSPVMVS-----NPATRMLKTAAAQVGTSVSSATNTSTRP 631 T++ P TT+ + SSP + + +T ++ + S AT T P Sbjct: 3507 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 3566 Query: 632 I-----ITVHKSGTVTVAQQAQVVTTVVGGVT------KTITLVKSPIS----VPGGSAL 676 + + +S T ++ + T + G T K+ T SP S + S Sbjct: 3567 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT 3626 Query: 677 ISNLGKVMSVVQTKP--VQTSAVTGQASTGPVTQIIQTKGPLPAGT---ILKLVTSADGK 731 S + + + ++P T+A +T +++ T P T +L T+ G Sbjct: 3627 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGS 3686 Query: 732 PTTIITTTQASGAGTKPTILGISSVSP------STT---KPGTT--TIIKTIPMSAIITQ 780 +TT S +G+ T L S + STT PG+T T+ S+ I + Sbjct: 3687 SQE--STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 3744 Query: 781 AG-----ATGV---------TSSPGIKSPITIITTK-VMTSGTGAPAKIITA-VPKIATG 824 A +TG ++SPG++ T T T T +P TA V + T Sbjct: 3745 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 3804 Query: 825 HGQQGVTQVV------LKGAPGQPGTILRTVP--MGGVRLVTPVTVSAVKPAVTTLVVKG 876 H G T + TI + P G T S + T+ + G Sbjct: 3805 HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 3864 Query: 877 TTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITT-------LGTIATLSSQVINPTAI 929 +T +TTL T T S A +S+ S T ++ +G +T S T Sbjct: 3865 STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS 3924 Query: 930 TVSAAQTTLTAAGGLTTPTITMQPVSQPTQV---TLITAPSGVEAQPVHDLPVSILASPT 986 TVS A TT +T + P S T V + T+ E H P S + Sbjct: 3925 TVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLF 3984 Query: 987 TEQPTATVTIADS-----GQGDVQ---PGTVTLV-----CSNPPCETHETGTTNTATTTV 1033 TE T + +S Q P T+T + P + TGT + + Sbjct: 3985 TEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST 4044 Query: 1034 VANLGGHPQPTQVQ-FVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTAT 1092 + L G P+++ + S T ++ +++ + +P T + AT Sbjct: 4045 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA------TLSPAT 4098 Query: 1093 TATSNMAGQHGCSNP-PCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 T +S ++ + S+ P TH T ++ TT+ G + + + T A + Sbjct: 4099 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS----GLSQEPTTSHSSQGSTEATLSPGS 4154 Query: 1152 ATGALEAAQGSKSQCQTRQTSAT-------STTMTVMATGAPCSAGPL---LGPSMAREP 1201 T + Q + T T ++ + +T S G L L P+ + Sbjct: 4155 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214 Query: 1202 GGRSPAFV-QLAPLSSKVRLSSPSIKDLPAG----RHSHAVSTAA--MTRSSVGAGEPRM 1254 G + + Q P SS S PS +P HS ST + SS G Sbjct: 4215 GLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 4274 Query: 1255 APVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTA------TTS 1308 + S G + + + ++L T + + S T G+T TA TT Sbjct: 4275 STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTF 4334 Query: 1309 NAGSAQRVCSNPPCETHETGTTHTATTATSNGG----------TGQPEGGQQPPAGR--P 1356 + + P T +G + +TT+ S G T P Q+ A P Sbjct: 4335 YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP 4394 Query: 1357 CETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAG-----TALLAPF 1411 T T S G+T + S+G P++T+ H + S E P T +G T + + Sbjct: 4395 GSTDTTLSPGSTTASSLG---PESTTFHSSPGS-TETTLLPDNTTASGLLEASTPVHSST 4450 Query: 1412 PTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSA 1471 + +P T G + T + ++ + PP S E+ +T S + T ++ Sbjct: 4451 GSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTH 4510 Query: 1472 ITTTVSSTLTRAV-TTVTQSTPVPGPSVPPPEE------------LQVSPGPRQQLPPRQ 1518 + + S+TL R+ +T S+PV + P P SPG Q + Sbjct: 4511 FSAS-STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTM---H 4566 Query: 1519 LLQSASTALMGESAEVLSASQTPELPAAVDLSS--TGEPSSGQESAGSAVVATVVVQPPP 1576 +S +T+ GE + +S T + +A +S EP+S S GS Sbjct: 4567 FPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF------ 4620 Query: 1577 PTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQ 1636 P S S +Q T T+++ + + + + + + + E Sbjct: 4621 PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST 4680 Query: 1637 AVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLT----QQELA 1692 ++++ P T + + LG S E ++ + T + + Sbjct: 4681 TTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGR-SEESTTVHSSPVATATTPSPARSTTS 4739 Query: 1693 ALVQQQ-QLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTA 1751 LV++ + Q H P + A S S+ + ++ +T AL+ Sbjct: 4740 GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPT 4799 Query: 1752 TESLAPSN--TFVAPQPVVVASPAKLQAAATLTEVANGIESL 1791 + +P + T P+ + ++ A+ + NGI L Sbjct: 4800 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPL 4841 Score = 117 bits (293), Expect = 1e-25 Identities = 286/1297 (22%), Positives = 433/1297 (33%), Gaps = 187/1297 (14%) Query: 454 APPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAP 513 +P +T T + S S + A A + P +T + L+ S Sbjct: 1971 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 2030 Query: 514 VTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAG 573 + T+LP P S + T SSP+ A + A+ T + T S P Sbjct: 2031 METTALPGST--TTPGLSEKSTTFHSSPRSP--ATTLSPASTTSSGVSEESTTSHSRPGS 2086 Query: 574 TTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATN-TSTRPI 632 T T A TTT + +S + T +L + G S S T+ +S Sbjct: 2087 T---HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2143 Query: 633 ITVHKSGTVTVAQQAQVVTT-----------------VVGGVTKTITLVKSPISVPG--- 672 T G+ T Q TT G+ + T V S P Sbjct: 2144 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2203 Query: 673 --GSALISNLGKVMSVVQTKPVQTSAVTGQASTG--PV---TQIIQTKGPLPAGTILKLV 725 S+ L + QT P T ST PV T ++ G P Sbjct: 2204 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 2263 Query: 726 TSADGKPTTIITTTQASGAGTKP-----TILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780 T++ + I + +GT P T G + S PG+T I T+P S Sbjct: 2264 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT-TLPGSTTTPG 2322 Query: 781 AGATGVTSSPGIKSPITIITTKVMTS-GTGAPAKII---------TAVPKIATGHGQQGV 830 T +SP T ++ MTS G G + T P T G Sbjct: 2323 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 2382 Query: 831 TQVVLKGAPGQPGT-ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGT 889 + V +PG T + P VR P T + +PA T TT T T +G Sbjct: 2383 STTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHS-RPASTH-----TTLFTEDSTTSGL 2436 Query: 890 VSTSLAGAGGH-STSASLATPITT--LGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT 946 S A G ST L +TT LG +T T T+S A++T + G +T Sbjct: 2437 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGEST 2496 Query: 947 PTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQP 1006 P+ P+ T P + + + SP + P AT++ A + V Sbjct: 2497 PSRL-----SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS--PDATLSPATTTSSGVSE 2549 Query: 1007 GTVTLVCSNPPCETHETGTTNTATTTVVA--NLGGHPQPTQVQFVCDRQEAAASLVTSTV 1064 + T + P TH T ++ TT ++ + H P D AS TS Sbjct: 2550 ESST--SHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST----DTTLLPASTTTSGP 2603 Query: 1065 GQQNGSVVRVCSNPPCETHET-GTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123 Q++ + +H + G+T+TA + S A G + + T T Sbjct: 2604 SQESTT-----------SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 2652 Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 ++ + R + G+P +S A+ QG + QT S +T Sbjct: 2653 STTSSGIVEASTRVHSSTGSPRTT-LSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTA 2711 Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRL--SSPSIKDL-PAGRHSHAVSTA 1240 AP S P PA + S K + SSP P+ HS Sbjct: 2712 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 2771 Query: 1241 AMTRSSVGAGEPRMAPVCESL--------------QGGSPSTTVTVTALEAL-------- 1278 T S + G + + S SP+TT++ ++ +L Sbjct: 2772 ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT 2831 Query: 1279 -----------LCPSATVTQ--------VCSNPPCETHETGTTNTATTSNAGSAQRVCSN 1319 + P++T T V S+ P T T + TTS G + Sbjct: 2832 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHS 2891 Query: 1320 PPCETHETGTTHTATT------------ATSNGGTGQPEGGQQPPAGRPCETHQTT--ST 1365 P TH T T +TT + ++ TG P G T ++ ST Sbjct: 2892 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 2951 Query: 1366 GTTMS---VSVGALLPDATSSHRTVESGLEVAAAPS---------------VTPQAGTAL 1407 GTT+S + L+ ++T S R S E P +P++ A Sbjct: 2952 GTTLSPARSTTSGLVGESTPS-RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 3010 Query: 1408 LAPFPT--QRVCSNPPCETHETGTTHTA----TTVTSNMSSNQDPPPAASDQGEVESTQG 1461 L+P T V + G+THT +T TS +S Q+P + S QG E+T Sbjct: 3011 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLS--QEPTASHSSQGSTEATLS 3068 Query: 1462 DSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQ 1521 +T +S+L + TT S+P + P++ S P Sbjct: 3069 PG----------STTASSLGQQSTTF-HSSPGDTETTLLPDDTITSGLVEASTPTHSSTG 3117 Query: 1522 SASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSE 1581 S T L S+ + + SS PS +A V+T P T + Sbjct: 3118 SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPT- 3176 Query: 1582 VDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAA 1618 S + ++ TT G T L T +A Sbjct: 3177 -THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 3212 Score = 110 bits (275), Expect = 1e-23 Identities = 357/1670 (21%), Positives = 558/1670 (33%), Gaps = 221/1670 (13%) Query: 410 TSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPG 469 +SP +P + S A+ P + TL P ++ + + P Sbjct: 1529 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPS 1588 Query: 470 SSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQA---GKAPVTVTSLPAGVRMV 526 SS + P+ T P + T + TP +S + TV S P Sbjct: 1589 SSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTA 1648 Query: 527 V-PTQSAQGTVIG---SSPQMSGMAALAAAAAATQKI-----------PPSSAPTVLSVP 571 + PT+SA ++G +SP SG A +T P S T LS P Sbjct: 1649 LFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS-P 1707 Query: 572 AGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP 631 A TT + + + P + + P + P TA+ S + + + Sbjct: 1708 ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTT 1767 Query: 632 IITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKP 691 ++ T + TT++ T L+++ V S+ G + + P Sbjct: 1768 ASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVH------SSTGSPHTTLS--P 1819 Query: 692 VQTSAVTGQAST---GPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP 748 ++ G+++T P ++ P ++L T++ G P++ TT ++ + Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS---- 1875 Query: 749 TILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG----ATGVTSSPGI------------ 792 T LG S STT + T P A T +G +T SSPG Sbjct: 1876 TTLGRSE--ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTA 1933 Query: 793 --KSPITIITTKVMTSGTGAPAKIITAVPKIATG-HGQQGVTQVVLKGAPGQPGTILRTV 849 +S + + T +P +A+ + T H G T P T R+ Sbjct: 1934 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSGRSE 1991 Query: 850 PMGGVRLVTPVTVSAVKPAVTT---LVVKGTTGVTTLGTVTGTV---STSLAGAGGHSTS 903 T + V PA +T L+ + TT + G++ T ST+ G ST+ Sbjct: 1992 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT 2051 Query: 904 --ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVT 961 +S +P TTL +T SS V + + S +T T A P T P T Sbjct: 2052 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA----FPDSTTTPGLSRHSTT 2107 Query: 962 LITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETH 1021 ++P + LP S S +++ T + + S + PG+ T + T Sbjct: 2108 SHSSPGSTDTTL---LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTF 2164 Query: 1022 ETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCE 1081 + +T TT P T + + A++ V S+ G ++ S P Sbjct: 2165 HSSPGSTHTTLF-------PDSTTSSGIVE----ASTRVHSSTGSPRTTLSPASSTSPGL 2213 Query: 1082 THETGTTNTATTATSNMAGQHGCSNPPCETHET-----GTTNTATTAMSSVGANHQRDAR 1136 E+ T +T + P E T G+T T SS + H + Sbjct: 2214 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 2273 Query: 1137 ----RACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPL 1192 A+GT S +G + + T + S ST +T + Sbjct: 2274 IFHSSPDASGTTPSSAHSTTSG--------RGESTTSRISPGSTEITTL----------- 2314 Query: 1193 LGPSMAREPG-GRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGE 1251 P PG + +P S LS S+ L G S +RS G+ Sbjct: 2315 --PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES------TTSRSQPGSTH 2366 Query: 1252 PRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAG 1311 ++P + G S +T V S+ P T T T TTS G Sbjct: 2367 STVSPASTTTPGLSEESTT-----------------VYSSSPGSTETTVFPRTPTTSVRG 2409 Query: 1312 SAQRVCSNPPCETHETGTTHTATTA----TSNGGTGQPEGGQQ--PPAGRPCETHQTTST 1365 + P TH T T +TT+ S G P Q P + + ++T Sbjct: 2410 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 2469 Query: 1366 GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425 + S S G L A R+ SGL + PS L+P T+ + P T Sbjct: 2470 FPSSSGSTGTTLSPA----RSTTSGLVGESTPS--------RLSPSSTE-TTTLPGSPTT 2516 Query: 1426 ETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAV- 1484 + + + T TS S + PA + V S + S+ T ST T + Sbjct: 2517 PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLS 2576 Query: 1485 --TTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPE 1542 +T + S+P + P S ++ S TAL S LS Q Sbjct: 2577 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE-- 2634 Query: 1543 LPAAVDLSSTGEPSSGQ-------ESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEA 1595 S+T S G +S S+ + + T S LS Sbjct: 2635 -------STTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 2687 Query: 1596 QAGTTTLMV----TGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGE 1651 Q +TT T TP + + A A + + T + A G E Sbjct: 2688 QGESTTFQTHPASTHTTP---SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSE 2744 Query: 1652 PMDT--SEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAAL---VQQQQLQEAQAQ 1706 S A+ T H + G+ G++TT I E+ L L EA Sbjct: 2745 KSTIFHSSPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTTPGLSEASTT 2803 Query: 1707 -QQHHHLPTEALAPADSLN-DPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAP 1764 PT L+PA + ES G+ STV+ ST T L+ +T Sbjct: 2804 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS-PASTTTPGLSEEST---- 2858 Query: 1765 QPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQWF-DVGVIKGTNV 1823 V +SP +T T V + V+ + P P F + G Sbjct: 2859 -TVYSSSP-----GSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 2912 Query: 1824 MVTHYFLPPDD------AVPSDDDLG----TVPDYNQLKKQELQPGTAYKFRVAGINACG 1873 T + P A + DLG T P + L P + + G + Sbjct: 2913 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPS 2972 Query: 1874 RGPFSEISAFKTCLPGFPGAPCAIKIS----KSPDGAHLTWEPPSVTSGKIIEYSVYLAI 1929 R S S T LPG P P + S SP T P + TS + E S + Sbjct: 2973 R--LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES---ST 3027 Query: 1930 QSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAI 1979 SQ G ++ P + P+ S Q S+ + TT ++ Sbjct: 3028 SHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSL 3077 Score = 98.6 bits (244), Expect = 6e-20 Identities = 285/1361 (20%), Positives = 482/1361 (35%), Gaps = 206/1361 (15%) Query: 446 TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505 TL P ++ +P T P S+ + P+ T P T ++ TP T P Sbjct: 3759 TLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP-TTHFP 3817 Query: 506 ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565 AS S + T+ SSP SG +A + + + Sbjct: 3818 ASSTTSG-----------------HSEKSTIFHSSPDASGTTPSSAHSTTSGR----GES 3856 Query: 566 TVLSVPAGTTIVKTMAVTPGTTTLP----ATVKVASSPVMVSNPATRMLKTAAAQVGTSV 621 T + G+T + T+ PG+TT P A+ SSP +P T + + +G Sbjct: 3857 TTSRISPGSTEITTL---PGSTTTPGLSEASTTFYSSP---RSPTTTLSPASMTSLGVGE 3910 Query: 622 SSATNTS----TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSP---ISVPGGS 674 S T+ S T ++ + T +++++ V + G T+T +S + + Sbjct: 3911 ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPT 3970 Query: 675 ALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSAD--GKP 732 S + + T+ TS +T +++ P + T+ LPA +T+AD + Sbjct: 3971 TFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA-STQTGLPA-----TLTTADLGEES 4024 Query: 733 TTIITTTQASGAGTKP---TILGI------SSVSPSTTKPGTTTIIKTIPMSAIITQAGA 783 TT +++ ++G P T G+ S +SPS+T+ TT + P + +++ Sbjct: 4025 TTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTE---TTTLPGSPTTPSLSEKST 4081 Query: 784 TGVTS--SPGIK-SPITIITTKVM----TSGTGAPAKIITAVP----------KIATGHG 826 T TS SP SP T ++ V TS + + TA P + T H Sbjct: 4082 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHS 4141 Query: 827 QQGVTQVVLK------GAPGQPGTILRTVPMGGVRLVTP---VTVSAVKPAVTTLVVKG- 876 QG T+ L + GQ T + P + P +T V+ + T G Sbjct: 4142 SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 4201 Query: 877 --TTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAIT---- 930 TT T TG S S+S + +P +T +S+ + + T Sbjct: 4202 LHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTH 4261 Query: 931 VSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQP 990 SA+ TTL + TT + P + T + + + V P+S ++ TT P Sbjct: 4262 FSASSTTLGRSEESTT--VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 4319 Query: 991 TATVTIADSGQGDV---QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGH----PQP 1043 +T T S + P + S P T +G + +TT+ H P Sbjct: 4320 GSTTTAGLSEKSTTFYSSPRSPDTTLS--PASTTSSGVSEESTTSHSRPGSMHTTAFPSS 4377 Query: 1044 TQVQFVCDRQEAAASLVTST-VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQH 1102 T + V A+ S ST GS P T + +T TT + Sbjct: 4378 TTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTAS 4437 Query: 1103 GCSNPPCETHETGTTNTATTAMSSVGAN-------------HQRDARRACAAGTPAVIRI 1149 G H + T + T +S G+ + +D A T A + + Sbjct: 4438 GLLEASTPVHSS--TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 4495 Query: 1150 SVATGALEAAQGSKSQCQTRQTSATSTTM-----TVMATGAPCSAGPLLGPSMAREPGGR 1204 S + GS S T SA+STT+ + +P + P+ + G Sbjct: 4496 STTS------HGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 4549 Query: 1205 SPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQG- 1263 + + S + P + +GR + ++ + T ++ + + + E Sbjct: 4550 EESTTYHSSPGSTQTMHFPE-SNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY 4608 Query: 1264 -GSPSTTVTVTALEALLCPSATVTQVCSNPPCETHE----TGTTNTATTSNAGSAQRVCS 1318 SP +T T P ++ T S +H TGT S + Sbjct: 4609 HSSPGSTATTHF------PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGEST 4662 Query: 1319 NPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTST-------GTTMSV 1371 P + TT + T+ G + + P+ P +ST TT+ Sbjct: 4663 TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHS 4722 Query: 1372 SVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE--THETGT 1429 S A + + T +E + A +P G+ FP S E T + T Sbjct: 4723 SPVATATTPSPARSTTSGLVEESTAYHSSP--GSTQTMHFPESSTASGRSEESRTSHSST 4780 Query: 1430 THTATTVTSNMSSN-QDPPPAASDQGEVESTQGDSVNITS--SSAITTTVSSTLTRAVT- 1485 THT ++ S S+ ++P S G + +T + TS S T + SS T +T Sbjct: 4781 THTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITP 4840 Query: 1486 --------------------------TVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQL 1519 T+ + PG S S P Q L P + Sbjct: 4841 LPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASM 4900 Query: 1520 LQSASTALMGESAEVLS---ASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP 1576 S+++ GE + S ++ T PA+ S + S+ S + T + P Sbjct: 4901 ---TSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETT--LSPGS 4955 Query: 1577 PTQSEVDQ-----LSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQ 1631 T S Q S P ++ +TT V GL+ EE ++ + + A + Sbjct: 4956 ITTSSFAQEFTTPHSQPGSALSTVSPASTT--VPGLS-EESTTFYSSPGSTETTAFSHSN 5012 Query: 1632 ALAIQAVLQAAQQAVMGTGEPMDT-SEAAATVTQAELGHLS 1671 ++I +QQ+ P T + AT+T ++G S Sbjct: 5013 TMSIH-----SQQSTPFPDSPGFTHTVLPATLTTTDIGQES 5048 Score = 92.8 bits (229), Expect = 3e-18 Identities = 319/1529 (20%), Positives = 509/1529 (33%), Gaps = 242/1529 (15%) Query: 435 PAVQPLTQVGI--TLLPQA---APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV 489 P P+T + T LP + A +TT P P ++S P + GV Sbjct: 252 PKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLS-PARTTSSGVSEKSTT 310 Query: 490 T----GPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS--PQM 543 + GP T P T P + S+P T + GT SS P+ Sbjct: 311 SHSRPGPTHTIAFPDSTTMPG--VSQESTASHSIPGST----DTTLSPGTTTPSSLGPES 364 Query: 544 SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVS 603 + + + T ++P ++ T + +T V + +P TT P+ SS Sbjct: 365 TTFHS-SPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPS-----SSTTHEG 416 Query: 604 NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITL 663 P T ++ + S T+ + T H S + T +T +G ++ + Sbjct: 417 EPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV 476 Query: 664 VKSPISV-----PGGSALISNLGKVMSV------VQTKPVQTSAVTGQASTGPVT---QI 709 SP++ P SA ++ + + QT S+ T S T Sbjct: 477 HSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGST 536 Query: 710 IQTKGPLPAGTILKLVTS----------------------------ADGKPTTIITTTQA 741 TK P+ T TS + P + TT Sbjct: 537 THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLP 596 Query: 742 SGAGTKPTILGISSVSP-------------STTKPG----------------TTTIIKTI 772 +G+ T ++G S+ SP STTKPG TT + ++ Sbjct: 597 AGS-TPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASM 655 Query: 773 PMSAIITQA-------GATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGH 825 S + ++ G+T T+ PG S ++ T+ +P T + +T Sbjct: 656 TSSGVSEESTTSHSRPGSTHTTAFPG--STTMPGLSQESTASHSSPGPTDTTLSPGSTTA 713 Query: 826 GQQGVTQVVLKGAPGQPGTIL---RTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT---G 879 G PG T L T G + PV S P TTL G+T G Sbjct: 714 SSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPH-TTLSPAGSTTRQG 772 Query: 880 VTTL---------------GTVTGTVSTSLAGAG-----------GHSTSASLATPITTL 913 +T T + V S G ST++ L TT Sbjct: 773 ESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTY 832 Query: 914 GTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQP 973 + + + P + T S T + TT TI+ P T L+ P+ + P Sbjct: 833 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP---STTSALVEEPTSYHSSP 889 Query: 974 ----VHDLPVSILASPTTEQPTATVTIADSGQGDVQP--GTVTLVCSNPPCETHETGTTN 1027 P S S +E+ TA+ + D+ V P T +++ +G+ Sbjct: 890 GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 949 Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGT 1087 T G + + R A ST + P TH T Sbjct: 950 TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAF 1009 Query: 1088 TNTATTATSNMAGQHGCSNP--------PCETHETGTTNTATTAMSSVGANHQRDARRAC 1139 ++ TT + S+P P T +G + +TT+ SS G+ A Sbjct: 1010 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTD-----TAL 1064 Query: 1140 AAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAG---PLLGPS 1196 + G+ + + + GS + S TS+ + +T S G L P+ Sbjct: 1065 SPGSTTALSFGQESTTFHSNPGS-THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 1123 Query: 1197 MAREPG--GRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRM 1254 + PG G S AF Q P S+ S PS P V + S G+ Sbjct: 1124 SSTSPGLQGESTAF-QTHPASTHTTPSPPSTATAP-------VEESTTYHRSPGSTPTTH 1175 Query: 1255 APVCESLQGGSPSTTVTVTALEAL-LCPSATVTQVCSNPPCETHETGTTNTATTSNAGSA 1313 P + G S +T+ ++ +A PS+ + T +T T+ GS Sbjct: 1176 FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 1235 Query: 1314 QRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPA-GRPCETHQTTSTGTTMSVS 1372 + T + TT + T G + + +P TH T S +T + Sbjct: 1236 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAST---T 1292 Query: 1373 VGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHET----- 1427 L ++T+ + + E P T T++ PT + P TH T Sbjct: 1293 TPGLSEESTTVYSSSRGSTETTVFPHSTT---TSVHGEEPT--TFHSRPASTHTTLFTED 1347 Query: 1428 ----GTTHTATTVTSNMSSNQDPPPA---ASDQGEVESTQGDSVNITS---SSAITTTV- 1476 G T +T + +S Q PA +D GE +T S T S A +TT Sbjct: 1348 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 1407 Query: 1477 ---SSTLTRAVTTVTQSTPVPG-PSVPPPEELQVS--PGPRQQLPPRQLLQSASTALMGE 1530 ST +R + T++T +PG P+ P E + PR P L A+T G Sbjct: 1408 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS---PDATLSPATTTSSGV 1464 Query: 1531 SAEVLSASQTP---ELPAAVDLSSTG----EPSSGQESAGSAVVATVVVQPPPPTQSEVD 1583 S E ++ P A D ++T EP++ S GS + P T S + Sbjct: 1465 SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGS---TEATLSPGSTTASSLG 1521 Query: 1584 QLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAA------TEEAQALAIQA 1637 Q Q + G T T L P++ + EA+ + T A + A Sbjct: 1522 Q----QSTTFHSSPGDTE---TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA 1574 Query: 1638 VLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQ 1697 LQ DT+ + T A + + +T T A+ Sbjct: 1575 GLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP-----TTHFSASSTTL 1629 Query: 1698 QQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAP 1757 + +E+ AL P S + + ++ T AL ST T L+ Sbjct: 1630 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 1689 Query: 1758 SNT--FVAPQ-PVVVASPAKLQAAATLTE 1783 +T + +P+ P SPA ++ E Sbjct: 1690 KSTTFYSSPRSPDTTLSPASTTSSGVSEE 1718 Score = 89.4 bits (220), Expect = 3e-17 Identities = 228/1070 (21%), Positives = 379/1070 (35%), Gaps = 152/1070 (14%) Query: 410 TSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPG 469 +SP +P + S A+ P + TL P ++ + + P Sbjct: 4169 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPS 4228 Query: 470 SSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPT 529 SS + P+ T VP + T + TP +S T+L Sbjct: 4229 SSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASS---------TTL---------G 4270 Query: 530 QSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTL 589 +S + T + SSP +G A +A + + PT + +G+T +T A+ TTT Sbjct: 4271 RSEESTTVHSSPGATGTALFPTRSATSVLV---GEPTTSPISSGST--ETTALPGSTTTA 4325 Query: 590 PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP---IITVHKSGTVT--VA 644 + K + +P T + + G S S T+ S RP T S T V+ Sbjct: 4326 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS-RPGSMHTTAFPSSTTMPGVS 4384 Query: 645 QQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG 704 Q++ + G T+ SP GS S+LG + + P T +T Sbjct: 4385 QESTASHSSPGSTDTTL----SP-----GSTTASSLGPESTTFHSSPGSTETTLLPDNT- 4434 Query: 705 PVTQIIQTKGPL------------PAGTILKLVTSADGKPTTIITTTQASGAGTKPTILG 752 + +++ P+ PAG+ T+ G+ TT + + P Sbjct: 4435 TASGLLEASTPVHSSTGSPHTTLSPAGS-----TTRQGESTTFQSWPNSKDTTPAPPTTT 4489 Query: 753 ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPA 812 + V STT G+ + T SA T G + + T+ ++ V T+ T +PA Sbjct: 4490 SAFVELSTTSHGSPSSTPTTHFSASSTTLGRS--------EESTTVHSSPVATATTPSPA 4541 Query: 813 KIITA--VPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVT 870 + T+ V + T H G TQ + P T R T T+S+ + Sbjct: 4542 RSTTSGLVEESTTYHSSPGSTQTM--HFPESNTTSGRGEESTTSHSSTTHTISSAPSTTS 4599 Query: 871 TLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAIT 930 LV + T+ ++ G+ T + G S ++ A+ SSQ T I Sbjct: 4600 ALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST-----------ASHSSQDATGT-IV 4647 Query: 931 VSAAQTTLTAAGGLTTPTI---TMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTT 987 + A TT G TT I +M+ + P T T ++ H P S +PTT Sbjct: 4648 LPARSTTSVLLGESTTSPISSGSMETTALPGSTT--TPGLSEKSTTFHSSPSS---TPTT 4702 Query: 988 EQPTATVTIADSGQGDVQPGTVTLVCSNP-PCETHETGTTNTATTTVVANLGGHPQPTQV 1046 ++ T+ S + T V S+P T + +T + V + H P Sbjct: 4703 HFSASSTTLGRSEES-------TTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 4755 Query: 1047 QFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSN 1106 Q + + + AS + + S S+PP +T + H Sbjct: 4756 QTMHFPESSTASGRSEESRTSHSSTTHTISSPP---------STTSALVEEPTSYHSSPG 4806 Query: 1107 PPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQC 1166 TH ++ T+ + S ++ D TP + + E+ S Sbjct: 4807 SIATTHFPESSTTSGRSEESTASHSSPDTNGI----TPLPAHFTTSGRIAESTTFYIS-- 4860 Query: 1167 QTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIK 1226 + TT+ AT SA + S +R P L+P S ++S SI Sbjct: 4861 ----PGSMETTLASTATTPGLSAKSTILYSSSRSPD------QTLSPAS----MTSSSIS 4906 Query: 1227 DLPAGRHSHAVS--TAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSAT 1284 P +S A S T A S+ +G + + S G + +T L P + Sbjct: 4907 GEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETT----------LSPGSI 4956 Query: 1285 VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQ 1344 T + H + +T S A + S T + T TTA S+ T Sbjct: 4957 TTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSE-ESTTFYSSPGSTETTAFSHSNTMS 5015 Query: 1345 PEGGQQPP-AGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEV-----AAAPS 1398 Q P P TH T T + +G ++T+ H + ++ + A Sbjct: 5016 IHSQQSTPFPDSPGFTH-TVLPATLTTTDIG---QESTAFHSSSDATGTTPLPARSTASD 5071 Query: 1399 VTPQAGTALLAPFPTQR----VCSNPPCETHETGTTHTATTVTSNMSSNQ 1444 + + T ++P PT S+ T E+ T HT+ + TS + S + Sbjct: 5072 LVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTE 5121 Score = 80.5 bits (197), Expect = 2e-14 Identities = 257/1194 (21%), Positives = 395/1194 (33%), Gaps = 194/1194 (16%) Query: 618 GTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALI 677 G + S++T +S+ P T G VT + G L S S + + Sbjct: 175 GNTTSASTPSSSDPFTTFSDYGVS--------VTFITGSTATKHFLDSSTNSGHSEESTV 226 Query: 678 SNLGKVMSVVQTKPVQ--TSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTI 735 S+ G + P TS G+ T P+T LP T K TT Sbjct: 227 SHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGST---TTAGLSEKSTTF 283 Query: 736 ITTTQASGAGTKPTILGISSVSPSTT----KPGTTTIIKTIPMSAIITQAGATGVTSSPG 791 ++ ++ P S VS +T +PG T I A GV+ Sbjct: 284 YSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI------AFPDSTTMPGVSQEST 337 Query: 792 IKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851 I T ++ GT P+ + P+ T H G T+ T Sbjct: 338 ASHSIPGSTDTTLSPGTTTPSSL---GPESTTFHSSPGYTKTTRLPD--------NTTTS 386 Query: 852 GGVRLVTPVTVSAVKPAVTTLVVKGTT---GVTTLGTVTGTVSTSLAGAGGHSTSASLAT 908 G + TPV S P T TT TT + + TS A +G S L+T Sbjct: 387 GLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLST 446 Query: 909 PITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSG 968 T S + SA+ TTL +TP + + T +A SG Sbjct: 447 ---------TYHSSPSSTPTTHFSASSTTL-GHSEESTPVHSSPVATATTPPPARSATSG 496 Query: 969 --VEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET------ 1020 E+ H P S + T P ++ T S + G+ T S+ P T Sbjct: 497 HVEESTAYHRSPGS---TQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHT 553 Query: 1021 ---HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEA-----AASLVTSTVGQQNGSVV 1072 G+T T + + G + ++ A A S + VG S + Sbjct: 554 SYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPI 613 Query: 1073 RVCSNP----PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVG 1128 S P T + G + +TT S+ ++ P +G + +TT+ S G Sbjct: 614 SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSP-DTTHLPASMTSSGVSEESTTSHSRPG 672 Query: 1129 ANHQR-----------DARRACAAGTPAVIRISVATGALEAAQ-GSKSQCQTRQTSATST 1176 + H + +P +++ G+ A+ G + + +T T Sbjct: 673 STHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTET 732 Query: 1177 TMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRL-------SSPSIKDLP 1229 T+ T +A LL SM RSP L+P S R S PS KD Sbjct: 733 TLLPDNT----TASGLLEASMPVHSSTRSP-HTTLSPAGSTTRQGESTTFHSWPSSKDT- 786 Query: 1230 AGRHSHAVSTAAMTR-SSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQV 1288 R + +T+A S+ G P P + STT + S TQ Sbjct: 787 --RPAPPTTTSAFVEPSTTSHGSPSSIPTTHI---SARSTTSGLVEESTTYHSSPGSTQT 841 Query: 1289 CSNPPCET-----HETGTTNTATTSNAGSAQRVCS---NPPCETH----ETGTTHTATTA 1336 P +T E+ T++++TT SA S P H T TTH ++ Sbjct: 842 MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 901 Query: 1337 TSNGGTGQ---PEGGQQPPAGRPCETHQTTST----GTTMSVSVGAL----LPDAT---- 1381 T++G + + Q TTS TT +S G++ LP +T Sbjct: 902 TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 961 Query: 1382 ---------SSHRTVESGLEVAAAPS--VTPQAGTALLAPFPTQRVC-----SNPPCETH 1425 SS R+ + L A+ S V+ ++ T+ P T + P H Sbjct: 962 LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRH 1021 Query: 1426 ET------GTTHT----ATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITT- 1474 T G+T T A+T TS S ++S + + G + ++ TT Sbjct: 1022 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 1081 Query: 1475 ---------------TVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQL 1519 T SS + A T V ST P ++ P SPG Sbjct: 1082 HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS--STSPG---------- 1129 Query: 1520 LQSASTALMGESAEVLSASQTPELPAA-VDLSSTGEPSSGQ--------ESAGSAVVATV 1570 LQ STA A + P A V+ S+T S G S S Sbjct: 1130 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 1189 Query: 1571 VVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEA 1630 + P S S ++ T+ + L + ++A+ T + Sbjct: 1190 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 1249 Query: 1631 QALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLS--AEGQEGQATTI 1682 + L A +G GE TS + T + + S G ++TT+ Sbjct: 1250 SPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTV 1303 Score = 64.7 bits (156), Expect = 9e-10 Identities = 188/944 (19%), Positives = 316/944 (33%), Gaps = 138/944 (14%) Query: 886 VTG-TVSTSLAGAGGHSTSASLATPITTLG---------TIATLSSQVINPTAITVSAAQ 935 +TG TV+TS+ G +++ S + P TT T +T + ++ + + + + Sbjct: 164 ITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEE 223 Query: 936 TTLTAAGGLTTPTITMQPVSQPTQVTL---ITAPSGVEAQPVHDLPVSILASPTTEQPTA 992 +T++ +G T T T+ P T V + T+P + LP S + +E+ T Sbjct: 224 STVSHSGPGATGT-TLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTT 282 Query: 993 TVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDR 1052 + S + P T S+ E T + T +A P T + V Sbjct: 283 FYSSPRSPDRTLSPARTT---SSGVSEKSTTSHSRPGPTHTIA----FPDSTTMPGVSQE 335 Query: 1053 QEAAASLVTST-VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCET 1111 A+ S+ ST G+ P T + T TT + G Sbjct: 336 STASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPV 395 Query: 1112 HETGTTNTATTAMSSVGANHQ------------RDARRACAAGTPAVIRISVATGALEAA 1159 H + T + TT S H+ +D A + T A +++S Sbjct: 396 H-SSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLST------TY 448 Query: 1160 QGSKSQCQTRQTSATSTTMTVMATGAPCSAGPL---LGPSMAREPGG----------RSP 1206 S S T SA+STT+ P + P+ P AR RSP Sbjct: 449 HSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSP 508 Query: 1207 AFVQLAPLSSKVRLSSPSIKDLP-AGRHSHAVSTAAMT---------RSSVGAGEPRMAP 1256 Q S S + G +H S+ T SS+G+ E Sbjct: 509 GSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFR 568 Query: 1257 VCESLQGGSPST--------TVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS 1308 ++ G S + + T L A PS V +P T +T+ Sbjct: 569 DSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTT 628 Query: 1309 NAGSAQR---VCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTST 1365 G +++ S+P TTH + TS+G + + RP TH T Sbjct: 629 KPGLSEKSTTFYSSP----RSPDTTHLPASMTSSGVSEESTTSH----SRPGSTHTTAFP 680 Query: 1366 GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425 G+T ++ L ++T+SH +P L+P T P T Sbjct: 681 GST---TMPGLSQESTASHS--------------SPGPTDTTLSPGSTTASSLGPEYTTF 723 Query: 1426 ETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT 1485 + T TT+ P + G +E++ + S + ST + + Sbjct: 724 HSRPGSTETTLL---------PDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGES 774 Query: 1486 TVTQSTPVPGPSVPPP--------EELQVSPGPRQQLPPRQL-LQSASTALMGESAEVLS 1536 T S P + P P E S G +P + +S ++ L+ ES S Sbjct: 775 TTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHS 834 Query: 1537 ---ASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMA 1593 ++QT P + S GE S+ S+ + +++ P T + V++ + + Sbjct: 835 SPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA----PSTTSALVEEPTSYHS--S 888 Query: 1594 EAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPM 1653 TT + T + A+ ++ A T A + +VL + M Sbjct: 889 PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 948 Query: 1654 DTSEAAATVTQAELGHLSA---EGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHH 1710 +T+ + T L S ATT+ A + E + Sbjct: 949 ETTALPGSTTTPGLSERSTTFHSSPRSPATTLS--------PASTTSSGVSEESTTSRSR 1000 Query: 1711 HLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATES 1754 T A DS P + + + + LLP++ T S Sbjct: 1001 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 1044 >gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sapiens] Length = 1064 Score = 126 bits (316), Expect = 2e-28 Identities = 234/1098 (21%), Positives = 421/1098 (38%), Gaps = 177/1098 (16%) Query: 515 TVTSLPAGVRMVVPTQSAQGTVIGSSPQM-------SGMAALAAAAAATQKIPPSSAPTV 567 T+++ + + P A T + +SP G+ LA+ A ++ P T+ Sbjct: 18 TLSTATSTSHVTFPRAEATRTALSNSPHSRYLAEWPQGVPQLASPAPGHRENAPM---TL 74 Query: 568 LSVPAGTTIVKTMA---VTPGTTTLPAT---VKVASSP-------------------VMV 602 + P T I +T+ V+ T+T P + KV ++P + + Sbjct: 75 TTSPHDTLISETLLSSLVSSNTSTTPTSKFAFKVETTPPTVLVYLATTECVYPTSFIITI 134 Query: 603 SNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT 662 S+P T + T TS + T + +P+ TV ++ +T ++ T+ + T T Sbjct: 135 SHP-TSICVTTTQVTFTSSYTPTPVTQKPVTTVTRTYPMTTTEKG---TSAMISSPSTTT 190 Query: 663 LVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTIL 722 ++PI S+ +S + ++ T + + P I T P P T L Sbjct: 191 ARETPIVTVTPSSSVSATDTTFHTT----ISSTTRTTERTPLPTGSIHTTMSPTPVFTTL 246 Query: 723 KLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG 782 K ++ T+ IT+T ++S++ +T++P T + ++ MS I++ Sbjct: 247 KTAVTSTSPITSTITSTNT-----------VTSMTTTTSRPTATNTLSSL-MSNILS--- 291 Query: 783 ATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842 S+P P T +TT T+ T + ++T +P Sbjct: 292 -----STP---VPSTEMTTS-HTTDTNPLSTLVTTLPT---------------------- 320 Query: 843 GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHST 902 TI R+ TP + + + T+ V TT +T +TGT+S + S+ Sbjct: 321 -TITRS---------TPTSETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSS 370 Query: 903 SASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTL 962 + TP+T + T +++ + +++ S++ T + +T I+ P + T VT Sbjct: 371 QQTTETPMTPTTKLVTTTTETTSQSSLNFSSSAIYSTVS--TSTTAISSLPPTSGTMVTS 428 Query: 963 ITAPSGVEAQP------VHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNP 1016 + +P VHD + +P Q T + A S P T TL C+N Sbjct: 429 TNIVPTADLKPELILLEVHDQRIQ-AKNPRYSQTPFTSSTATS------PETTTLTCTN- 480 Query: 1017 PCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCS 1076 T T T+TT V++ + P+ T A+ T+T+ S++ Sbjct: 481 DISTESLTTAMTSTTPVISAI--TPKTTVTSMT---TTASGPTTTNTLSSLTSSILSSTP 535 Query: 1077 NPPCE--THETGTTNTATTATSNMAGQHGCSNPPCE-THETGTTNTATTAMSSVGANHQR 1133 P E T T TT +T + + S P E T+ T T T +M+ + + Sbjct: 536 APNTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTDSMTEITYSTSM 595 Query: 1134 DARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLL 1193 + A P S + +E A + T TS + + A S + Sbjct: 596 TGTWSTATTLPLT---SCSLPTIETATTPTTNLGNTTTETTSHSTPSFTSSAIYSTVNIS 652 Query: 1194 GPSMAREP--GGRSPAFVQLAPLSSKVRLSSPSIKDL------PAGRHSHAVS-TAAMTR 1244 +++ P G F + P S +S+ ++K++ G + A T+ T Sbjct: 653 TTTISSFPPSSGTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTSTFTV 712 Query: 1245 SSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCS-NPPCETHETGTTN 1303 SS A + P S+Q ST V+ T + P+ +T + N P T + Sbjct: 713 SSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTS---PTERMTLTSTENTPTSYILTTSPV 769 Query: 1304 TATTSNAGSAQ-------RVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRP 1356 T + S + SA S+ P T TT +T A + + +PP+ Sbjct: 770 TYSFSPSMSASSDWTTDTESISSAPAITSTLHTTAESTLAPTTTNSFTTSANMEPPS--- 826 Query: 1357 CETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRV 1416 TT TG + S A + T+ T + E P ++ T + + + Sbjct: 827 -TAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFMTPMIST---TPITSSMTLRNT 882 Query: 1417 CSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV 1476 ++ TT+T +++TS++ S+ P ST+ ITS + TT+ Sbjct: 883 MTSMTTAASRPTTTNTLSSLTSSILSSTPVP----------STE----VITSQTTNTTSP 928 Query: 1477 SSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGE-SAEV- 1534 S+ +T TT+T STP E S P + + ST++ G S E+ Sbjct: 929 STLVTTLPTTITTSTPT--------SETTYSTSPTSTVTDSTTETTYSTSITGTLSTEIS 980 Query: 1535 LSASQTPELPAAVDLSST 1552 L A+ + + + ++ST Sbjct: 981 LPATTSSLITKGISMTST 998 Score = 119 bits (298), Expect = 3e-26 Identities = 226/1046 (21%), Positives = 363/1046 (34%), Gaps = 154/1046 (14%) Query: 408 TATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT- 466 T+T+PT V PP A V P + + IT+ + P TT QV T Sbjct: 96 TSTTPTSKFAFKVETTPPTVLVYLATTECVYPTSFI-ITI---SHPTSICVTTTQVTFTS 151 Query: 467 ----VPGSSISVPTAARTQGVPAVLK-----VTGPQATTG--TPLVTMRPASQAGKAPVT 515 P + V T RT + K ++ P TT TP+VT+ P+S T Sbjct: 152 SYTPTPVTQKPVTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVTVTPSSSVSATDTT 211 Query: 516 V-TSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPP--------SSAPT 566 T++ + R T G++ + L A +T I +S T Sbjct: 212 FHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTT 271 Query: 567 VLSVPAGT-TIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKT------------- 612 S P T T+ M+ +T +P+T ++ +S +NP + ++ T Sbjct: 272 TTSRPTATNTLSSLMSNILSSTPVPST-EMTTSHTTDTNPLSTLVTTLPTTITRSTPTSE 330 Query: 613 ---AAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS 669 A+ T S T + ++T S T T+ + T +T T LV + Sbjct: 331 TTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKLVTTTTE 390 Query: 670 VPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSAD 729 S+L + + S V T ST ++ + T G + T +V +AD Sbjct: 391 TTSQSSLNFSSSAIYSTVST------------STTAISSLPPTSGTMVTST--NIVPTAD 436 Query: 730 GKPTTIITTTQASGAGTK-PTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTS 788 KP I+ K P S + T P TTT+ T + I T++ T +TS Sbjct: 437 LKPELILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCT---NDISTESLTTAMTS 493 Query: 789 SPGIKSPITIITTKV-MTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTIL- 846 + + S IT TT MT+ P T + +T +L P ++ Sbjct: 494 TTPVISAITPKTTVTSMTTTASGP----------TTTNTLSSLTSSILSSTPAPNTEVIT 543 Query: 847 ----RTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHST 902 T P + P ++ P T TG T T STS+ G +T Sbjct: 544 SHTTTTTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTDSMTEITYSTSMTGTWSTAT 603 Query: 903 SASLAT-PITTLGTIATLSSQVINPTAITVSAAQTTLTAAG-----GLTTPTITMQPVSQ 956 + L + + T+ T T ++ + N T T S + + T++ ++T TI+ P S Sbjct: 604 TLPLTSCSLPTIETATTPTTNLGNTTTETTSHSTPSFTSSAIYSTVNISTTTISSFPPSS 663 Query: 957 PTQVTLITAPSGVEAQPVHDLPVSILASPTTEQP---------TATVTIADSGQGDVQPG 1007 T VT T + + + + P+ T+T T++ S Sbjct: 664 GTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTSTFTVSSS-----SAM 718 Query: 1008 TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQ 1067 + ++ S P + E T + TTT PT+ + + S + +T Sbjct: 719 STSVTPSAPSIQNKEISTLVSTTTTT--------SPTERMTLTSTENTPTSYILTT---- 766 Query: 1068 NGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSV 1127 S V +P TT+T S+ P T TT +T A Sbjct: 767 --SPVTYSFSPSMSASSDWTTDT-----------ESISSAPAITSTLHTTAESTLA---- 809 Query: 1128 GANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPC 1187 P + +E + + T Q++ TS+T T + T Sbjct: 810 ----------------PTTTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLET---- 849 Query: 1188 SAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSV 1247 L P+ + P++S + L + A +T + SS+ Sbjct: 850 ---TTLTPTTDISTESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSI 906 Query: 1248 GAGEPRMAP---VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNT 1304 + P + ++ SPST VT + T ++P ++ T T Sbjct: 907 LSSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTDSTTETT 966 Query: 1305 ATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTS 1364 +TS G+ S P T T + T+T N T E H T S Sbjct: 967 YSTSITGTLSTEIS-LPATTSSLITKGISMTSTRNLVTTTNENTSHSTPTFTLTIHSTIS 1025 Query: 1365 TGTTMSVSVGALL-PDATSSHRTVES 1389 T TT SV P TS+ T S Sbjct: 1026 TSTTAISSVPTTSGPIVTSTTMTPSS 1051 Score = 94.4 bits (233), Expect = 1e-18 Identities = 149/641 (23%), Positives = 257/641 (40%), Gaps = 98/641 (15%) Query: 403 PATAATATSPTPNPVPSVPANPPKS--PAPAAAAPAVQPLT-QVGITLLPQAAPAPPTTT 459 P T++TATSP + +S A + P + +T + +T + A P TT Sbjct: 462 PFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVISAITPKTTVTSMTTTASGPTTTN 521 Query: 460 TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSL 519 T+ L + S +S A T+ + + T P +T LVT P + A P + T+ Sbjct: 522 TLSSLTS---SILSSTPAPNTEVITSHTTTTTPPST----LVTTLPTAIARSTPTSETTY 574 Query: 520 PAGVRMVVPTQSAQGTVIGSSPQMSGMAALAA--AAAATQKIPPSSAPTVLSVPA----- 572 P + PT GTV S +++ ++ + A T + S PT+ + Sbjct: 575 P-----ISPT----GTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNL 625 Query: 573 -GTTIVKTMAVTPGTTT--LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTST 629 TT T TP T+ + +TV ++++ + P++ + T +S+S+ +T+T Sbjct: 626 GNTTTETTSHSTPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTTT 685 Query: 630 RPIIT---VHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSV 686 IT V +G +T A TV + ++ S S+ IS L V + Sbjct: 686 LKNITQPSVGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKE--ISTL--VSTT 741 Query: 687 VQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAG------------TILKLVTSADGKPTT 734 T P + +T +T T I T P+ T + ++SA +T Sbjct: 742 TTTSPTERMTLTSTENTP--TSYILTTSPVTYSFSPSMSASSDWTTDTESISSAPAITST 799 Query: 735 IITTTQASGAGTKP-------------TILGISSVSPSTTKPGTTTIIKTI---PMSAII 778 + TT +++ A T T + + ST T T ++T P + I Sbjct: 800 LHTTAESTLAPTTTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDIS 859 Query: 779 TQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGA 838 T++ T + S+ I S +T+ T MTS T TA + T + +T +L Sbjct: 860 TESFMTPMISTTPITSSMTLRNT--MTSMT-------TAASRPTTTNTLSSLTSSILSST 910 Query: 839 P--------------GQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLG 884 P P T++ T+P + TP + + + T+ V TT T Sbjct: 911 PVPSTEVITSQTTNTTSPSTLVTTLPTT-ITTSTPTSETTYSTSPTSTVTDSTTETTYST 969 Query: 885 TVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGL 944 ++TGT+ST ++ +T++SL T G T + ++ T S + T T Sbjct: 970 SITGTLSTEISLP---ATTSSLITK----GISMTSTRNLVTTTNENTSHSTPTFTLTIHS 1022 Query: 945 TTPTITMQPVSQP-TQVTLITAPSGVEAQPVHDLPVSILAS 984 T T T S P T ++T+ + + D+P + L + Sbjct: 1023 TISTSTTAISSVPTTSGPIVTSTTMTPSSLTADIPTTTLTT 1063 Score = 57.0 bits (136), Expect = 2e-07 Identities = 91/481 (18%), Positives = 177/481 (36%), Gaps = 73/481 (15%) Query: 401 DIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTT 460 +I T ++ P+ + + P S + + ++ +TQ + A T+T Sbjct: 650 NISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTST 709 Query: 461 IQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLP 520 V + S+ P+A Q V+ T+ T +T+ + + TS Sbjct: 710 FTVSSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTSPTERMTLTSTENTPTSYILTTS-- 767 Query: 521 AGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580 SP MS A++ T SSAP + S T+ Sbjct: 768 -------------PVTYSFSPSMS-----ASSDWTTDTESISSAPAITS---------TL 800 Query: 581 AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGT 640 T +T P T ++ + P+ TA A GT S+ T+++ + T + T Sbjct: 801 HTTAESTLAPTTTNSFTTSANMEPPS-----TAVATTGTGQSTFTSSTATFLETTTLTPT 855 Query: 641 VTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ 700 ++ ++ + T + +PI+ S + N M+ ++P T+ ++ Sbjct: 856 TDISTESFM----------TPMISTTPIT---SSMTLRNTMTSMTTAASRPTTTNTLSS- 901 Query: 701 ASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPST 760 +T I + P+P+ ++ T+ P+T++TT + + PT S SP++ Sbjct: 902 -----LTSSILSSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTS 956 Query: 761 TKPGTTT-------IIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAK 813 T +TT I T+ + ++ +T + S ++TT + P Sbjct: 957 TVTDSTTETTYSTSITGTLSTEISLPATTSSLITKGISMTSTRNLVTTTNENTSHSTPTF 1016 Query: 814 IITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLV 873 +T I+T + + P G I+ + M TP +++A P T Sbjct: 1017 TLTIHSTIST-------STTAISSVPTTSGPIVTSTTM------TPSSLTADIPTTTLTT 1063 Query: 874 V 874 + Sbjct: 1064 I 1064 Score = 47.8 bits (112), Expect = 1e-04 Identities = 78/408 (19%), Positives = 141/408 (34%), Gaps = 60/408 (14%) Query: 400 YDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLP---QAAPAPP 456 + + +++A +TS TP+ AP+ + L T P + Sbjct: 710 FTVSSSSAMSTSVTPS-------------APSIQNKEISTLVSTTTTTSPTERMTLTSTE 756 Query: 457 TTTTIQVLPTVPGS-SISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVT 515 T T +L T P + S S +A + ++ A T T + +++ AP T Sbjct: 757 NTPTSYILTTSPVTYSFSPSMSASSDWTTDTESISSAPAITST----LHTTAESTLAPTT 812 Query: 516 VTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT 575 S M P+ + T G S S A T S+ + + + T Sbjct: 813 TNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFMTPMISTTP 872 Query: 576 IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635 I +M + T++ ++ +S+ + +L + ++S T +T P V Sbjct: 873 ITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSILSSTPVPSTEVITSQTTNTTSPSTLV 932 Query: 636 HKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTS 695 T TT T T+ T Sbjct: 933 TTLPTTITTSTPTSETTYSTSPTSTV--------------------------------TD 960 Query: 696 AVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTT--IITTTQASGAGTKPTILGI 753 + T + +T + T+ LPA T L+T +T ++TTT + + + PT Sbjct: 961 STTETTYSTSITGTLSTEISLPA-TTSSLITKGISMTSTRNLVTTTNENTSHSTPTF--- 1016 Query: 754 SSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITT 801 +++ +T +TT I ++P ++ T SS P T +TT Sbjct: 1017 -TLTIHSTISTSTTAISSVPTTSGPIVTSTTMTPSSLTADIPTTTLTT 1063 Score = 43.1 bits (100), Expect = 0.003 Identities = 100/520 (19%), Positives = 178/520 (34%), Gaps = 52/520 (10%) Query: 1301 TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH 1360 ++NT+TT + A +V + PP T + ATT P + +H Sbjct: 93 SSNTSTTPTSKFAFKVETTPP-----TVLVYLATTECV-----------YPTSFIITISH 136 Query: 1361 QTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFP-------T 1413 T+ TT V+ + + + V + P T + GT+ + P T Sbjct: 137 PTSICVTTTQVTFTSSYTPTPVTQKPVTT--VTRTYPMTTTEKGTSAMISSPSTTTARET 194 Query: 1414 QRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSV---NITSSS 1470 V P T TT T ++ ++ + P P S + T + +TS+S Sbjct: 195 PIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTS 254 Query: 1471 AITTTVSST--LTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALM 1528 IT+T++ST +T TT ++ T S L +P P ++ + + + Sbjct: 255 PITSTITSTNTVTSMTTTTSRPTATNTLSSLMSNILSSTPVPSTEMTTSHTTDTNPLSTL 314 Query: 1529 GESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPP---PPTQSEVDQL 1585 + TP S T + + V T + P PPT S Sbjct: 315 VTTLPTTITRSTPTSETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSS---- 370 Query: 1586 SLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQA 1645 Q+ TT L+ T T E + ++ +++ +T AI ++ + Sbjct: 371 ---QQTTETPMTPTTKLVTT--TTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPTSGTM 425 Query: 1646 VMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPI---VLTQQELAALVQQQQLQ- 1701 V T + T++ + E+ + + + + P T E L + Sbjct: 426 VTST-NIVPTADLKPELILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTNDIST 484 Query: 1702 EAQAQQQHHHLPT-EALAP---ADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAP 1757 E+ P A+ P S+ A N L+ S ++ P+ TE + Sbjct: 485 ESLTTAMTSTTPVISAITPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTPAPNTEVITS 544 Query: 1758 SNTFVAPQPVVVAS-PAKLQAAATLTEVANGIESLGVKPD 1796 T P +V + P + + +E I G D Sbjct: 545 HTTTTTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTD 584 >gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo sapiens] Length = 2036 Score = 119 bits (297), Expect = 4e-26 Identities = 278/1192 (23%), Positives = 421/1192 (35%), Gaps = 206/1192 (17%) Query: 512 APVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVL--- 568 A + TS + + T + I + S + + A AT +P S P+VL Sbjct: 35 AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGD 94 Query: 569 --SVPAGTTIVKTMAVTPGTTTLPATVKVA----SSPVMVSNPATRMLKTAAAQVGTSVS 622 P + ++T A+ PG+TT P + + SSP +P T L + G S Sbjct: 95 STPSPISSGSMETTAL-PGSTTKPGLSEKSTTFYSSP---RSPDTTHLPASMTSSGVSEE 150 Query: 623 SATNTSTRP--IITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNL 680 S T+ S RP T G+ T+ +Q T T T + SP GS S+L Sbjct: 151 STTSHS-RPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTL-SP-----GSTTASSL 203 Query: 681 GKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL------------PAGTILKLVTSA 728 G + ++P T +T + +++ P+ PAG+ T+ Sbjct: 204 GPEYTTFHSRPGSTETTLLPDNT-TASGLLEASMPVHSSTRSPHTTLSPAGS-----TTR 257 Query: 729 DGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG----AT 784 G+ TT + + P + V PSTT G+ + I T +SA T +G +T Sbjct: 258 QGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEEST 317 Query: 785 GVTSSPGIKSPITIITTKVMTSGTG----------------APAKIITAVPKIATGHGQQ 828 SSPG + + TSG G AP+ V + + H Sbjct: 318 TYHSSPGSTQTMHFPESDT-TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 376 Query: 829 GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTT---LVVKGTTGVTTLGT 885 G T P T R+ T + V PA +T L+ + TT + G+ Sbjct: 377 GSTATT--HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 434 Query: 886 VTGTV---STSLAGAGGHSTS--ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTA 940 + T ST+ G ST+ +S +P TTL +T SS V + + S +T T Sbjct: 435 METTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTT 494 Query: 941 AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000 A P T P T ++P + LP S S +++ T + + + S Sbjct: 495 A----FPDSTTTPGLSRHSTTSHSSPGSTDTTL---LPASTTTSGPSQESTTSHSSSGST 547 Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060 + PG+ T + T + +T TT P T + + A++ V Sbjct: 548 DTALSPGSTTALSFGQESTTFHSNPGSTHTTL-------FPDSTTSSGIVE----ASTRV 596 Query: 1061 TSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHET-----G 1115 S+ G ++ S P E+ T +T + P E T G Sbjct: 597 HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG 656 Query: 1116 TTNTATTAMSSVGANHQRDA----RRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQT 1171 +T T SS + H + A+GT S +G + + T + Sbjct: 657 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG--------RGESTTSRI 708 Query: 1172 SATSTTMTVMATGAPCSAGPLLGPSMAREPG-GRSPAFVQLAPLSSKVRLSSPSIKDLPA 1230 S ST +T + P PG + +P S LS S+ L Sbjct: 709 SPGSTEITTL-------------PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGV 755 Query: 1231 GRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVT----ALEALLCPSATVT 1286 G S +RS G+ ++P + G S +T + + E + P +T T Sbjct: 756 GEES------TTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTT 809 Query: 1287 QV-------CSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTA--- 1336 V + P TH T T +TTS P T +TG T TTA Sbjct: 810 SVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST-QTGLPATLTTADLG 868 Query: 1337 -------TSNGGTGQP-----------EGGQQPPAGRPCETHQTTSTG--TTMSVS---- 1372 +S+G TG G P P T TT G TT S+S Sbjct: 869 EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 928 Query: 1373 ---VGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFP---TQRVCSNPPCETHE 1426 PDAT S T S + + Q G+ FP T S P +H Sbjct: 929 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS 988 Query: 1427 T-GTTHTATTVTSNMSSN--QDPPPAASDQGEVESTQGDSVNITSS--SAITTTVSS--- 1478 + G+T + S +S+ Q S G+ E+T ITS A T T SS Sbjct: 989 SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 1048 Query: 1479 ---TLTRAVTT----------------VTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQL 1519 TLT A +T + +TP P + P E+ + R P Sbjct: 1049 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1108 Query: 1520 LQSASTALMGESAEVLSASQTPELPAAVDLSS-------TGEPSSGQESAGS 1564 ++ST L G S E + +P + GEP++ S+GS Sbjct: 1109 FSASSTTL-GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGS 1159 Score = 117 bits (293), Expect = 1e-25 Identities = 283/1292 (21%), Positives = 472/1292 (36%), Gaps = 178/1292 (13%) Query: 405 TAATATSPTPNPVPSVPANPPKSPAPAAAAPAV-QPLTQVGITLLPQAAPAPPTTTTIQV 463 T A+ PV S +P + +PA + + T PAPPTTT+ V Sbjct: 226 TTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFV 285 Query: 464 LP--TVPGSSISVPT---AARTQGVPAVLKVTGPQATTGTPLVTMRPASQA--------- 509 P T GS S+PT +AR+ V + T ++ G+ P S Sbjct: 286 EPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEEST 345 Query: 510 ---GKAPVTVTSLPAGVRMVV--PTQ------SAQGTVIGSSPQMSGMAALAAAAAATQK 558 T++S P+ +V PT S T S SG + + A+ ++Q Sbjct: 346 TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD 405 Query: 559 ------IPPSSAPTVL-----SVPAGTTIVKTMAVTPGTTTLPA----TVKVASSPVMVS 603 +P S +VL + P + ++T A+ PG+TT P + SSP Sbjct: 406 ATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL-PGSTTTPGLSERSTTFHSSP---R 461 Query: 604 NPATRMLKTAAAQVGTSVSSATNT----STRPIITVHKSGTVTVAQQAQVVTTVVGGVTK 659 +PAT + + G S S T+ ST + T +++ + + G Sbjct: 462 SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 521 Query: 660 TITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVT-GQASTGPVTQIIQTKGPL-P 717 T+ + S P + S+ + P T+A++ GQ ST + T L P Sbjct: 522 TLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFP 581 Query: 718 AGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI 777 T + A T +S + T+ SS SP G +T +T P S Sbjct: 582 DSTTSSGIVEAS-------TRVHSSTGSPRTTLSPASSTSPGL--QGESTAFQTHPASTH 632 Query: 778 ITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG 837 T + + T++ ++ T + T T PA T +GH ++ + Sbjct: 633 TTPSPPS--TATAPVEESTTYHRSPGSTPTTHFPASSTT------SGHSEK---STIFHS 681 Query: 838 APGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGA 897 +P GT + T S + T+ + G+T +TTL T T S A Sbjct: 682 SPDASGTTPSSAHS---------TTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAST 732 Query: 898 GGHSTSASLATPITT-------LGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTIT 950 +S+ S T ++ +G +T S T TVS A TT +T + Sbjct: 733 TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS 792 Query: 951 MQPVSQPTQV---TLITAPSGVEAQPVHDLPVSI---------LASPTTEQPTATVTIAD 998 S T V + T+ G E H P S S TE+ TA Sbjct: 793 SSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 852 Query: 999 SGQGDVQPGTVTLV-----CSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQ-FVCDR 1052 S Q + P T+T + P + TGT + + + L G P+++ + Sbjct: 853 STQTGL-PATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 911 Query: 1053 QEAAASLVTSTVGQQNGSVVRVCSNP-----PCETHETGTTNTATTATSNMAGQHGCSNP 1107 S T ++ +++ + +P P T +G + ++T+ S H + P Sbjct: 912 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP 971 Query: 1108 -----------PCETHET-----GTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 P +H + T + +T SS+G T + ++ Sbjct: 972 DSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 1031 Query: 1152 ATGALEAA---QGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAF 1208 +G +EA+ S T T A+ST+ + + P P G + A Sbjct: 1032 TSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP-SSSDTTPSPPGTTAAP 1090 Query: 1209 VQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV--CESLQGGSP 1266 V+++ S+P+ + + SS GA + P S+ G P Sbjct: 1091 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 1150 Query: 1267 STT-VTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETH 1325 +T+ ++ + E P +T T S + + + T S A + S +H Sbjct: 1151 TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1210 Query: 1326 -ETGTTHTATTATSNGGTGQPEGGQQPPAGR--PCETHQTTSTGTTMSVSVGALLPDATS 1382 G+THT G T P Q+ A P T T S G+T + S+G P++T+ Sbjct: 1211 SRPGSTHTTAFP---GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG---PESTT 1264 Query: 1383 SHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT--HTATTVTSNM 1440 H + S E P T +G L A P +P G+T +T + Sbjct: 1265 FHSSPGS-TETTLLPDNTTASG-LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1322 Query: 1441 SSNQD----PPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA-VTTVTQSTPVPG 1495 S++D PP S E+ +T S + T ++ + + S+TL R+ +T S+PV Sbjct: 1323 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS-STTLGRSEESTTVHSSPVAT 1381 Query: 1496 PSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLS---ASQTPELPAAVDLSST 1552 + P P +S ++ L+ ES S ++QT P + S Sbjct: 1382 ATTPSP------------------ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGR 1423 Query: 1553 GEPSSGQESAGSAVVATVVVQPPPPTQSEVDQ 1584 E S S+ + +++ PP T + V++ Sbjct: 1424 SEESRTSHSSTTHTISS----PPSTTSALVEE 1451 Score = 94.4 bits (233), Expect = 1e-18 Identities = 278/1258 (22%), Positives = 433/1258 (34%), Gaps = 194/1258 (15%) Query: 427 SPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAV 486 S AP+ + V+ T ++P TT T G S + +Q Sbjct: 356 SSAPSTTSALVEEPTSY------HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT 409 Query: 487 LKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGM 546 + + P +T + L+ S + T+LP P S + T SSP+ Sbjct: 410 IVL--PARSTTSVLLGESTTSPISSGSMETTALPGST--TTPGLSERSTTFHSSPRSP-- 463 Query: 547 AALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPA 606 A + A+ T + T S P T T A TTT + +S + Sbjct: 464 ATTLSPASTTSSGVSEESTTSRSRPGST---HTTAFPDSTTTPGLSRHSTTSHSSPGSTD 520 Query: 607 TRMLKTAAAQVGTSVSSATN-TSTRPIITVHKSGTVTVAQQAQVVTT------------- 652 T +L + G S S T+ +S+ T G+ T Q TT Sbjct: 521 TTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLF 580 Query: 653 ----VVGGVTKTITLVKSPISVPG-----GSALISNLGKVMSVVQTKPVQTSAVTGQAST 703 G+ + T V S P S+ L + QT P T ST Sbjct: 581 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 640 Query: 704 G--PV---TQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSP 758 PV T ++ G P T++ + I + +GT P SS Sbjct: 641 ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP-----SSAHS 695 Query: 759 STTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818 +T+ G +T + P S IT G T++PG+ T S +P ++ Sbjct: 696 TTSGRGESTTSRISPGSTEITTL--PGSTTTPGLSEAST-----TFYSSPRSPTTTLSPA 748 Query: 819 PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPV-------TVSAVKPAVTT 871 + G G++ T G+ + T G T V T + V P TT Sbjct: 749 SMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTT 808 Query: 872 LVVKG--------------TTGVTTLGTVTGTVSTSLAGAGGH-STSASLATPITT--LG 914 V G TT T T +G S A G ST L +TT LG Sbjct: 809 TSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG 868 Query: 915 TIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPV 974 +T T +S A++T + G +TP+ P+ T P + Sbjct: 869 EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRL-----SPSSTETTTLPGSPTTPSL 923 Query: 975 HDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVV 1034 + + SP + P AT++ A + V + T + P TH T ++ TT+ + Sbjct: 924 SEKSTTFYTSPRS--PDATLSPATTTSSGVSEESST--SHSQPGSTHTTAFPDSTTTSDL 979 Query: 1035 ANLGGHPQPTQVQFVCDRQEAA---ASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091 + +PT EA S S++GQQ+ T + +T Sbjct: 980 SQ-----EPTTSHSSQGSTEATLSPGSTTASSLGQQS------------TTFHSSPGDTE 1022 Query: 1092 TTATSNMAGQHGCSNPPCETHE-TGTTNTATTAMSSVGANHQRDARR-----ACAAGTPA 1145 TT + G TH TG+ +T T SS A Q ++ + + TP+ Sbjct: 1023 TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS 1082 Query: 1146 VIRISVATGALEAAQGSK-SQCQTRQTSATSTTM-----TVMATGAPCSAGPLLGPS--- 1196 + A + S+ S T SA+STT+ + +P + G L P+ Sbjct: 1083 PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 1142 Query: 1197 ---MAREP------GGRS-----PAFVQLAPLSSKVRL--SSPSIKDL---PAGRHSHAV 1237 + EP G + P A LS K SSP D PA S V Sbjct: 1143 TSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV 1202 Query: 1238 STAAMT-RSSVGAGEPRMAPVCESLQGGSPSTTVTVTA---LEALLCPSATVTQVCSNPP 1293 S + T S G+ P ++ G S +T + ++ + L P +T T P Sbjct: 1203 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGST-TASSLGPE 1261 Query: 1294 CETHETGTTNTATT---SNAGSAQRVCSNPPCETHETGTTHTATT-ATSNGGTGQPEGGQ 1349 T + +T TT N ++ + ++ P + TG+ HT + A S G+ Q Sbjct: 1262 STTFHSSPGSTETTLLPDNTTASGLLEASTPVHS-STGSPHTTLSPAGSTTRQGESTTFQ 1320 Query: 1350 QPPAGR------PCETH-----QTTSTGTTMSVSVGALLPDATSSHRTVES----GLEVA 1394 P+ + P T TTS G+ S +T+ R+ ES VA Sbjct: 1321 SWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 1380 Query: 1395 AAPSVTP-----------------QAGTALLAPFPTQRVCSNPPCE--THETGTTHTATT 1435 A + +P G+ FP S E T + TTHT ++ Sbjct: 1381 TATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS 1440 Query: 1436 VTSNMSS-NQDPPPAASDQGEVESTQGDSVNITS--SSAITTTVSSTLTRAVTTVTQSTP 1492 S S+ ++P S G + +T + TS S T + SS T +T + Sbjct: 1441 PPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFT 1500 Query: 1493 VPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLS 1550 G + +SPG + L +A+T + + +L S P +S Sbjct: 1501 TSG-RIAESTTFYISPGSME----TTLASTATTPGLSAKSTILYTSDLVGEPTTFYIS 1553 Score = 71.2 bits (173), Expect = 9e-12 Identities = 135/622 (21%), Positives = 226/622 (36%), Gaps = 78/622 (12%) Query: 410 TSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPG 469 +SP +P + S A+ P + TL P ++ + + P Sbjct: 1016 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPS 1075 Query: 470 SSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPT 529 SS + P+ T P + T + TP +S T+L Sbjct: 1076 SSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS---------TTL---------G 1117 Query: 530 QSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTL 589 +S + T + SSP +G A +A + + PT + +G+T +T A+ TTT Sbjct: 1118 RSEESTTVHSSPGATGTALFPTRSATSVLV---GEPTTSPISSGST--ETTALPGSTTTA 1172 Query: 590 PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP--IITVHKSGTVTVAQQA 647 + K + +P T + + G S S T+ S RP T G+ T+ + Sbjct: 1173 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS-RPGSTHTTAFPGSTTMPGVS 1231 Query: 648 QVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVT 707 Q T T T + SP GS S+LG + + P T +T + Sbjct: 1232 QESTASHSSPGSTDTTL-SP-----GSTTASSLGPESTTFHSSPGSTETTLLPDNT-TAS 1284 Query: 708 QIIQTKGPL------------PAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISS 755 +++ P+ PAG+ T+ G+ TT + + P + Sbjct: 1285 GLLEASTPVHSSTGSPHTTLSPAGS-----TTRQGESTTFQSWPSSKDTMPAPPTTTSAF 1339 Query: 756 VSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKII 815 V STT G+ + T SA T G + + T+ ++ V T+ T +PA+ Sbjct: 1340 VELSTTSHGSPSSTPTTHFSASSTTLGRS--------EESTTVHSSPVATATTPSPARST 1391 Query: 816 TA--VPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLV 873 T+ V + H G TQ + P R+ T T+S+ + LV Sbjct: 1392 TSGLVEESTAYHSSPGSTQTM--HFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 1449 Query: 874 VKGTTGVTTLGTVTGTVSTSLAGAGGHS--TSASLATP----ITTLGTIATLSSQVINPT 927 + T+ ++ G++ T + G S ++AS ++P IT L T S ++ T Sbjct: 1450 EEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAEST 1509 Query: 928 AITVSAAQTTLTAAGGLTTPTI--------TMQPVSQPTQVTLITAPSGVEAQPVHDLPV 979 +S T A TTP + T V +PT + +P+ P Sbjct: 1510 TFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTLFPASSSTS 1569 Query: 980 SILASPTT--EQPTATVTIADS 999 + TT P+ T TI + Sbjct: 1570 GLTEESTTFHTSPSFTSTIVST 1591 Score = 44.7 bits (104), Expect = 0.001 Identities = 134/683 (19%), Positives = 222/683 (32%), Gaps = 101/683 (14%) Query: 1296 THETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGR 1355 T TT+T +++ + +A ++ T TTH ++T +G + + + P Sbjct: 18 TFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP--- 74 Query: 1356 PCETHQTT--STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAG--------- 1404 + TT G+T SV VG P SS +E A P T + G Sbjct: 75 --DAMATTVLPAGSTPSVLVGDSTPSPISS-----GSMETTALPGSTTKPGLSEKSTTFY 127 Query: 1405 --------TALLAPFPTQRVCSNPPCETHETGTTHTAT--TVTSNMSSNQDPPPAASDQG 1454 T L A + V G+THT T+ +Q+ + S G Sbjct: 128 SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPG 187 Query: 1455 EVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQL 1514 ++T S T++S++ ++ +R +T T P + E + + Sbjct: 188 PTDTTL--SPGSTTASSLGPEYTTFHSRPGSTETTLLP-DNTTASGLLEASMPVHSSTRS 244 Query: 1515 PPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTG--EPSSGQESAGSAVVATVVV 1572 P L + ST GES S + + A +++ EPS+ + S++ T + Sbjct: 245 PHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHI- 303 Query: 1573 QPPPPTQSEVDQLSLPQELMAEAQAGTTTLM------VTGLTPEELAVTAAAEAAAQAAA 1626 +S L + + + G+T M T EE + ++ ++A Sbjct: 304 ----SARSTTSGL-VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 358 Query: 1627 TEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQE---------- 1676 AL + + T D+S + ++ H S + Sbjct: 359 PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 418 Query: 1677 ----GQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHH----LPTEALAPADSLNDPAI 1728 G++TT PI E AL + H P L+PA + + Sbjct: 419 SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 478 Query: 1729 ESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQP---VVVASPAKLQAAATLTEVA 1785 E + + T A ST T L+ +T P PA + E Sbjct: 479 EESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 538 Query: 1786 NGIESLGVKPDLPPPPSKAPMK--KENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLG 1843 S G P S + +E+ F +N TH L PD S G Sbjct: 539 TSHSSSGSTDTALSPGSTTALSFGQESTTFH------SNPGSTHTTLFPDSTTSS----G 588 Query: 1844 TVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSP 1903 V ++ P T +S + PG G A + P Sbjct: 589 IVEASTRVHSSTGSPRTT------------------LSPASSTSPGLQGESTAFQ--THP 628 Query: 1904 DGAHLTWEPPSVTSGKIIEYSVY 1926 H T PPS + + E + Y Sbjct: 629 ASTHTTPSPPSTATAPVEESTTY 651 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 118 bits (296), Expect = 5e-26 Identities = 318/1437 (22%), Positives = 489/1437 (34%), Gaps = 190/1437 (13%) Query: 417 VPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPT 476 +P +P+ PA AA P V P G +TI + P S++V T Sbjct: 357 IPPLPSRNEVVPATVAAFPVVAPSVDKG-------------PSTISSITCSPSGSLNVAT 403 Query: 477 AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTV 536 + +++ + P AT PLV P S G P+ VT+ P + PT + + Sbjct: 404 SFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTN-PCTI-AAAPTTTFEVAT 461 Query: 537 IGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVA 596 S P SG + + + AP S TT+ + V+P P +K Sbjct: 462 CVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL--RIPVSPPLPD-PEDLKNL 518 Query: 597 SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGG 656 S V+V P + L+T A S+ A + + +T K TV QA + Sbjct: 519 PSSVLVKFPTQKDLQTVPA----SLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNS--PS 572 Query: 657 VTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL 716 T + + P+S P + +LG+ + + + TS + G S+ V + GP Sbjct: 573 FQSTSSSPEIPLS-PEATLAKKSLGEPLPIGKPASSMTSPL-GVNSSASVIKTDSYAGPD 630 Query: 717 PAGTILK--LVT---------SADGKPTTIITTTQASGAGT-----KPTILGISSVSPST 760 AG +LK L+T SAD P + TT A G T P + G S++P Sbjct: 631 SAGPLLKSSLITPTVAAFPLESAD--PAGVAPTT-AKGTSTYTTTASPFLEGTVSLAPKN 687 Query: 761 --TKPGTTTIIKTIPM---------SAIITQAGATGVTSSPGIKSPITIITTKVMTSGTG 809 K GT T + +P S T A + +P I P ++ + + +GT Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEI--PKSVPSPSLPPAGTP 745 Query: 810 APAKII------TAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVS 863 K + +A+ +A+ + GT+ +P+ VS Sbjct: 746 PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS-----PSPLGVS 800 Query: 864 AVKPAVTTLVVKGTTGV-TTLGTVTGTVS---------TSLAGAGGHSTSASL--ATPIT 911 KG+ G T +G ++ VS SL+ G + A+ TP + Sbjct: 801 VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860 Query: 912 TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTP---TITMQPVSQPTQVTLITAPSG 968 G + ++P +T+ +T + L P T P P ++P Sbjct: 861 PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920 Query: 969 VEAQPVHDLPVSILASPTTE-QPTATVTIADSGQGDVQPGTVT-LVCSNPPCETHETGTT 1026 A P P I ASP+ + PT S +G P T + PP T + Sbjct: 921 ARATPA---PKGIPASPSPKGAPTPPAATPPSPKGG--PATPSPKWAPTPPAATPPSPKG 975 Query: 1027 NTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG 1086 AT + G P P A+ S G + PP T + Sbjct: 976 GPATPSP----KGAPTP------------PAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019 Query: 1087 TTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAV 1146 + A T G S PP T + + A T + GA A G P Sbjct: 1020 KGSPAATPFPK-----GASTPPAATPPSPKGSPAATPLPK-GAPTTPAATLPSPKGGP-- 1071 Query: 1147 IRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSP 1206 AT +L+ A + +T A P + P +A P +P Sbjct: 1072 -----ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126 Query: 1207 AFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSP 1266 P S K L++P P G + +T + + P+ AP + SP Sbjct: 1127 TTPAATPPSPKGGLATPP----PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182 Query: 1267 STTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHE 1326 + + P T + PP + AT S G+ + PP Sbjct: 1183 KGGLATPS------PKGAPTTPAATPP-----SPKGGLATPSPKGAPTTPAATPPSPKGG 1231 Query: 1327 TGTTHTATTATSNGGT-GQPEGG--QQPPAGRPCETHQTTSTGTTMSVSVG-ALLPDATS 1382 T T+ T P+GG PP G P T T S+ G A P + Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAP-----TPPAATPPSLKGGLATPPHKGA 1286 Query: 1383 SHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSS 1442 + V + P+ +P G AP P + PP GT T + Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKG----APTPP---AATPPSPKGSPGTPPPKGAPTPPAVT 1339 Query: 1443 NQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPE 1502 P + S++G +S T ++ + +T +P GP++P P+ Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399 Query: 1503 ELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQ-TPELPAAVDLS---STGEPSSG 1558 SP + P ++ +T + E A S TP V L +T P G Sbjct: 1400 GDPTSPA----VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455 Query: 1559 QESAGSAVVATV-VVQPP----PPTQSEVDQLSLPQELMA-EAQAGTTTL-MVTGLTPEE 1611 + S T+ V PP PP +V S P++ A A G TL V +P+E Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515 Query: 1612 LAVTAAA--EAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGH 1669 + T ++ + A A + A A +A M P T A T +A Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT-PAIPTPKEAPATP 1574 Query: 1670 LSAEGQEGQATT--------------IPIVLT-----QQELAALVQQQQLQEAQAQQQHH 1710 S E A T IP +T + V ++ A Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK 1634 Query: 1711 HLPTEALAPADSLND-PAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQP 1766 PT SL D P ++ ++ TVP LP+ + A VAP P Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT-ALKEVLVAPAP 1690 Score = 103 bits (256), Expect = 2e-21 Identities = 348/1565 (22%), Positives = 528/1565 (33%), Gaps = 252/1565 (16%) Query: 367 PARVQLVRANTNSLEVSWGAVATADS-YLLQLQKYDIPATAATATSPTPNPVPSVPANPP 425 P VQ A +L S +VA A+S ++ L P+ T + P+ V P P Sbjct: 144 PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTP 203 Query: 426 KSPAPAAAAP--AVQPLTQV--GITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQ 481 P + P V P+ + G+ LPQ P TTT P V ++IS + Sbjct: 204 SPPCIVSTVPYHCVTPMASIQSGVASLPQTTP---TTTLAIASPQVKDTTISSVLISPQN 260 Query: 482 GVPAVLKVTGPQA--------TTGTPLVTMRPASQAGKAPVTVTSLPA--GVRMVVPTQS 531 P L + GP + T P+VT +SQ P T P G + QS Sbjct: 261 --PGSLSLKGPVSPPAALSLSTQSLPVVT---SSQKTAGPNTPPDFPISLGSHLAPLHQS 315 Query: 532 AQGTVIGSSPQMSGMAALAAAAAATQK-IPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLP 590 + G+V Q+ G +A + T K I + T S P+ +++ + +P Sbjct: 316 SFGSV-----QLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSR--NEVVP 368 Query: 591 ATVKV--ASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP----IITVHKSGTVTVA 644 ATV +P + P+T + + S++ AT+ S P I+ + T Sbjct: 369 ATVAAFPVVAPSVDKGPST--ISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYP 426 Query: 645 QQAQVVTTVVGG----VTKTITLVKSP---------ISVPGGSALISNL------GKVMS 685 AQ+ + VG VT T+ +P +S P S ISN+ VM+ Sbjct: 427 LVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMA 486 Query: 686 VVQTKPVQTS-AVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQAS-- 742 V K T A T + P + LP+ ++K T D + T AS Sbjct: 487 PVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKD------LQTVPASLE 540 Query: 743 GAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIK-SPITIITT 801 GA P G+++ T P +++ P ++ Q+ +SSP I SP + Sbjct: 541 GAPFSPAQAGLTTKKDPTVLP----LVQAAPKNSPSFQS----TSSSPEIPLSPEATLAK 592 Query: 802 KVMTSGT--GAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTP 859 K + G PA +T+ + + V + P G +L++ L+TP Sbjct: 593 KSLGEPLPIGKPASSMTSPLGV---NSSASVIKTDSYAGPDSAGPLLKS------SLITP 643 Query: 860 VTV-----SAVKPAVTTLVVKGTTGVTTLGT--VTGTVSTSLAGAGGHSTSASLATPITT 912 SA V KGT+ TT + + GTVS + H +TT Sbjct: 644 TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA---PKNHPVKEGT---LTT 697 Query: 913 LGTIATLSSQV-INPTAITVSAAQTTLTAAGGL--TTPTITMQPVSQPTQVTLITAPSGV 969 L + T S + P+ A TL A + + P+ ++ P P + S Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS-- 755 Query: 970 EAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV--QPGTVTLVCSNP-PCETHETGTT 1026 H ++ +AS E PT DSG GT+T + +P P + T Sbjct: 756 -----HTSALAPVASSPKECPTE-----DSGASATASSKGTLTYLADSPSPLGVSVSPQT 805 Query: 1027 NTATT--------TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNP 1078 T T + NL P + F+ + S G ++ P Sbjct: 806 KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS-------LSFQGSKDSPATTHSPTP 858 Query: 1079 PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNT-------ATTAMSSVGANH 1131 P + + T +A T S G + PP ET N AT A A Sbjct: 859 P--SPKGAPTPSAVTPLS----PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912 Query: 1132 QRDARRACAAGTPAVIRISVATGALEA-AQGSKSQCQTRQTSATSTTMTVMATGAPCSAG 1190 + A TPA I + A + + + AT + A Sbjct: 913 MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972 Query: 1191 PLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLP--------AGRHSHAVST--- 1239 P GP+ G +P P S K ++PS K P + + S A + Sbjct: 973 PKGGPATPSPKGAPTPPAA--TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030 Query: 1240 AAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHET 1299 A T + P+ +P L G+P TT T P+ + PP T + Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAP-TTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089 Query: 1300 GTTNTATTSNAGSAQRVCSNPPCETHETGTT-HTATTATSNGGTGQPEGG--QQPPAGRP 1356 AT S G+ + PP T H T P+GG PP G P Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149 Query: 1357 CETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRV 1416 TT T S G P + T P+ TP + LA P+ + Sbjct: 1150 -----TTPAATPPSPKGGLATPPPKGAPTT----------PAATPPSPKGGLAT-PSPKG 1193 Query: 1417 CSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV 1476 P T + AT + PAA+ S +G + A TT Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTT----PAATPP----SPKGGLATPSPKGAPTTPA 1245 Query: 1477 SSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPG------------PRQQLPPRQLLQSAS 1524 + T +P GP+ PPP+ P P + P + + Sbjct: 1246 A----------TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295 Query: 1525 TALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQ 1584 + G + + TP PAA S G P + A V PP P + Sbjct: 1296 SPKGGPATSPPKGAPTP--PAATPPSPKGSPGTPPPKGAPTPPA---VTPPSPKGTP--- 1347 Query: 1585 LSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQAL-------AIQA 1637 +LP + TT G TP + A + + A+ A Sbjct: 1348 -TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406 Query: 1638 VLQAAQQAVMGTGEPMDTSEAAAT----------VTQAELGHLSAEGQEGQATTIPIVLT 1687 V+ + + T P+ T E AAT VT L A P Sbjct: 1407 VIPLSPKKAPAT--PV-TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463 Query: 1688 QQELAALVQQQQLQE-AQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVAL 1746 L A+ + A Q P +A A + P + + + + P V Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA-----VIPSSPKEVPA 1518 Query: 1747 LPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPS--KA 1804 PS+ + +AP+ T ++ + +PA L L A + S P +P P Sbjct: 1519 TPSSRRDPIAPTATLLSKK-----TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT 1573 Query: 1805 PMKKE 1809 P KE Sbjct: 1574 PSSKE 1578 Score = 101 bits (251), Expect = 9e-21 Identities = 317/1433 (22%), Positives = 477/1433 (33%), Gaps = 217/1433 (15%) Query: 418 PSVPANPPKSPAPAAAAPAV-----------QPLTQVGITLLPQAAPAPPTTTTIQVLPT 466 P+V A P +S PA AP P + ++L P+ P T T LP Sbjct: 643 PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLT--TLPL 700 Query: 467 VPGSSISVPTAARTQGV--PAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVR 524 VP +S + P A Q P V P+ P ++ PA P G + Sbjct: 701 VPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT-----------PPGTK 749 Query: 525 MV--VPTQSAQGTVIGSSPQM----SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVK 578 V + SA V S + SG +A A++ + S +P +SV T Sbjct: 750 KVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809 Query: 579 TMAVTPGTTTLPATVKVASSPVMVS--------------NPATRMLKTAAAQVGTSVSSA 624 T + G T + SPV S +PAT T + G SA Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869 Query: 625 TN-------------TSTRPIITVH--KSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS 669 T T ++ + K G T A + ++ K +P Sbjct: 870 VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929 Query: 670 VPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILK-----L 724 +P + + P +A GP T + PA T Sbjct: 930 IPASPS-----------PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978 Query: 725 VTSADGKPTTIITTTQASGAGTK-------PTILGISSVSPSTTKPGTTTIIK---TIPM 774 S G PT T + G PT ++ SP + P T K T P Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS-PAATPFPKGASTPPA 1037 Query: 775 SAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVV 834 + + G+ T P T G P+ P AT +G Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097 Query: 835 L-KGAPGQPGTILRTVPMGGVRLVTPVTVSA-VKPAVTTLVVKGTTGVTT---LGTVTGT 889 KGAP P + P GG L TP A PA T KG G+ T G T Sbjct: 1098 SPKGAPMPPAATPPS-PKGG--LATPPHKGAPTTPAATPPSPKG--GLATPPPKGAPTTP 1152 Query: 890 VSTSLAGAGGHST-------SASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG 942 +T + GG +T + ATP + G +AT S P + A T + G Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS-----PKGAPTTPAATPPSPKG 1207 Query: 943 GLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQG 1002 GL TP+ P T +P G A P S +PTT P AT G Sbjct: 1208 GLATPSPKGAPT---TPAATPPSPKGGLATP------SPKGAPTT--PAATPPSPKGGPA 1256 Query: 1003 DVQP-GTVTLVCSNPP------CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEA 1055 P G T + PP G N A T + GG P + + Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG-PATSPPK---GAPTP 1312 Query: 1056 AASLVTSTVGQQNGSVVRVCSNPPCETHET--GTTNTATTATSNMAGQHGCSNPPCETHE 1113 A+ S G + PP T + GT T S+ G P + + Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG------PTTPSSK 1366 Query: 1114 TGTTNTATTAMSSVG-ANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTS 1172 G T A T G A +R A +P S A L + + TR+ + Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV-TREGA 1425 Query: 1173 ATST--------TMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPS 1224 AT + V AP ++ P GP+ G P + P S K + Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG--DPTLPAVTPPSPKEPPAPKQ 1483 Query: 1225 IKDLPAGRHSHAVST--AAMTRSSVGAGEPRMAPVCESLQGG---------SPSTTVTVT 1273 + + + + A A T +V P+ P S + S T T+ Sbjct: 1484 VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA 1543 Query: 1274 ALEALLCPSATVTQVCSNP----PCETHETGTTN--------TATTSNAGSAQRVCSNPP 1321 EAL+ P+ TV P P E T ++ T +T + + PP Sbjct: 1544 PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP 1603 Query: 1322 CETH----ETGTTHTATTATSNGG--TGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGA 1375 T E T T + G T P+G P P + ++ +++ +GA Sbjct: 1604 AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA 1663 Query: 1376 LLPDATSS-----HRTVESGLEVAAAPSVTPQAGTALLAPFPTQR-------VCSNPPCE 1423 +P A+ T + VA AP TP T++ +C +P + Sbjct: 1664 TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723 Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 G T + +D A + S +G S A T ++ + Sbjct: 1724 NGSKGPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPKGPLAP-PESKASTPLTAAAFEKV 1781 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGES-AEVLSASQTPE 1542 + ++ PS PP L ++P P LPP+Q +S L+ ES ++ L+ + E Sbjct: 1782 LPKPESASVSAAPS--PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDE 1839 Query: 1543 LPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTL 1602 L + EP SG G + +V P P + ++ + + G+ T Sbjct: 1840 LLPLI----PPEPISG----GVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTE 1891 Query: 1603 MVTGLTPEEL-------AVTAAAEAAAQAAATEEAQALAIQAVLQ-AAQQAVMGTGEPMD 1654 + + EL A T A+ AA A EE + A Q+ + A++A+ G Sbjct: 1892 SDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQV 1951 Query: 1655 TSEAAATVTQAE---LGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQ 1704 T T+ +++ + + A+ IV + ++ L QQ QL A+ Sbjct: 1952 TGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAE 2004 Score = 95.9 bits (237), Expect = 4e-19 Identities = 336/1602 (20%), Positives = 506/1602 (31%), Gaps = 313/1602 (19%) Query: 402 IPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTI 461 +P A T +P A P +A + L Q G TL P +PAP Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALS-VTAALGQPGPTLPPPCSPAPQ----- 54 Query: 462 QVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521 P +A Q P P TPL P S +G T+LP Sbjct: 55 -----------QCPLSAANQASP----FPSPSTIASTPLEVPFPQSSSG------TALPL 93 Query: 522 GVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQK-IPPSSAPTVLSVPAGTTIVKTM 580 G PT +IG + +A + A T K P SSAP L A ++ K+ Sbjct: 94 GTAPEAPT--FLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSS 151 Query: 581 AVTPGTTTLPATVKVA--------SSPVMVSNPATRMLKTAAAQV----GTS-----VSS 623 A P T P +V VA S+P+ S P T + K + V GT VS+ Sbjct: 152 AFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVST 211 Query: 624 ATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKV 683 P+ ++ +SG ++ Q T + T + S + P +S G V Sbjct: 212 VPYHCVTPMASI-QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPV 270 Query: 684 MS------VVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT 737 Q+ PV TS+ Q + GP T P+ G+ L + + ++ Sbjct: 271 SPPAALSLSTQSLPVVTSS---QKTAGPNT---PPDFPISLGSHLAPLHQSSFGSVQLLG 324 Query: 738 TTQASGAGTKPTILGISSVSPST--TKPGTTTIIKTIP-MSAIITQAGATGVTSSPGI-K 793 T S A + PT+ IS ST + P ++I +P + ++ A +P + K Sbjct: 325 QTGPS-ALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDK 383 Query: 794 SPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG----------QPG 843 P TI + SG+ +AT T ++LK +P P Sbjct: 384 GPSTISSITCSPSGS----------LNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPV 433 Query: 844 TILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTS-----LAGAG 898 + + T P+ +VT A P T V + + G ++ TS +A Sbjct: 434 SSVGTTPL----VVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA 489 Query: 899 GHSTSASLAT--------PITTLGTIATLSSQVI--NPTAITVSAAQTTLTAA------G 942 S +AT P+ + L S V+ PT + +L A Sbjct: 490 PKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549 Query: 943 GLTT-------PTITMQPVSQPTQVTLITAPSGVEAQPVHDL-------------PVSIL 982 GLTT P + P + P+ + ++P + P L P S + Sbjct: 550 GLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPE-IPLSPEATLAKKSLGEPLPIGKPASSM 608 Query: 983 ASPTTEQPTATVTIADSGQGDVQPG------TVTLVCSNPPCETHETG--------TTNT 1028 SP +A+V DS G G +T + P E+ + T+T Sbjct: 609 TSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTST 668 Query: 1029 ATTTVVANLGG--------HP-----------QPTQVQ---FVCDRQEAAASLVTSTVGQ 1066 TTT L G HP PT + Q A L T + Sbjct: 669 YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP 728 Query: 1067 QNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMS- 1125 + V S PP T GT + ++ S C T ++G + TA++ + Sbjct: 729 EIPKSVPSPSLPPAGT-PPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787 Query: 1126 ------------SVGANHQRDARRACAAGTPAVI-RISVATGALEAA---------QGSK 1163 SV +R + +AG I +S +EA+ QGSK Sbjct: 788 TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847 Query: 1164 SQCQTRQ-----------TSATSTTMTVMATGAPCSAGPLLGPSMAREP----GGRSPAF 1208 T T + T ++ P P PS+ P G +PA Sbjct: 848 DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT--PSVVNLPFPKEGPATPAP 905 Query: 1209 VQLAPL-----SSKVRLSSPSIKDLPA-----GRHSHAVSTAAMTRSSVGAGEPRMAPVC 1258 Q L S K ++P+ K +PA G + +T + P+ AP Sbjct: 906 KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965 Query: 1259 ESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCS 1318 + SP P+ + PP T + AT S G+ Sbjct: 966 PAATPPSPKGG-----------PATPSPKGAPTPPAATPPSPKGGPATPSPKGA-----P 1009 Query: 1319 NPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLP 1378 PP T + A T G + P P G P T TT + ++ + P Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--P 1067 Query: 1379 DATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCET------------HE 1426 + +++ AA +P+ G A P+ + PP T H+ Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPAT----PSPKGAPMPPAATPPSPKGGLATPPHK 1123 Query: 1427 TGTTHTATTVTSNMSSNQDPPP---AASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483 T A T S PPP + S +G A TT + Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA------ 1177 Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 T +P G + P P+ +P P L S P Sbjct: 1178 ----TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-------------SPKGAPTT 1220 Query: 1544 PAAVDLSSTGEPSSGQESAGSAVVATVVVQP------PPPTQSEVDQLSLPQELMAEAQA 1597 PAA S G ++ A P PPP + + P L + Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL----KG 1276 Query: 1598 GTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSE 1657 G T G P VT + A + + A A + + GT P Sbjct: 1277 GLATPPHKG-APNPAVVTPPSPKGGPATSPPKG-APTPPAATPPSPKGSPGTPPPKGAPT 1334 Query: 1658 AAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEAL 1717 A + G T+P + + H A+ Sbjct: 1335 PPAVTPPSPKG----------TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384 Query: 1718 APADSLNDPAIESNCLNELAGTV----PSTVALLPSTATESLAPSNTFVAPQPVVVASPA 1773 P PAI S + + V P P T + PS + P V +P Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV---TPV 1441 Query: 1774 KLQAAATLTEVANGIESLGVKPD------LPPPPSKAPMKKE 1809 L+ A + G + K D PP P + P K+ Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483 Score = 54.7 bits (130), Expect = 9e-07 Identities = 89/386 (23%), Positives = 135/386 (34%), Gaps = 68/386 (17%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 PA ATS +P P+ PA P A PAV P + P+ PA P++ Sbjct: 1479 PAPKQVATSSSPKKAPATPA-----PMGAPTLPAVIPSS-------PKEVPATPSSRRDP 1526 Query: 463 VLPTVPGSSISVPT--AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGK--------A 512 + PT S P A + +P + V P+ T P PA+ + K Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586 Query: 513 PVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP--TVLSV 570 P T P+ +++P V SP+ A + +K P + AP T S Sbjct: 1587 PSTYKGAPSPKELLIPP-----AVTSPSPK-EAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640 Query: 571 PAGTTIVKTMAVTPGTTT--LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTS 628 P + +K +P + T + ATV AS + T + + A S Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST------- 1693 Query: 629 TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQ 688 PIIT T G TK + PI P SA + G + +V Sbjct: 1694 --PIIT---------------APTRKGPQTKKSSATSPPI-CPDPSAKNGSKGPLSTVAP 1735 Query: 689 TKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP 748 + + + + G KGPL + K +T +T KP Sbjct: 1736 APLLPVQKDSSKTAKGKDAS-HSPKGPL---------APPESKASTPLTAAAFEKVLPKP 1785 Query: 749 TILGISSV-SPSTTKPGTTTIIKTIP 773 +S+ SP + P + + T+P Sbjct: 1786 ESASVSAAPSPPVSLPLAPSPVPTLP 1811 Score = 50.4 bits (119), Expect = 2e-05 Identities = 93/426 (21%), Positives = 153/426 (35%), Gaps = 69/426 (16%) Query: 406 AATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLP 465 AAT + P P + K+PA +A P+ PA P++ LP Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSA----------------PKGGPATPSSKGDPTLP 1468 Query: 466 TVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRM 525 V S P A + V + P+ TP AP+ +LPA Sbjct: 1469 AVTPPSPKEPPAPK-----QVATSSSPKKAPATP------------APMGAPTLPA---- 1507 Query: 526 VVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPG 585 VI SSP+ A ++++ P + T+LS T+ A+ P Sbjct: 1508 ----------VIPSSPKE------VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551 Query: 586 TTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQ 645 T+P+ K + P PAT K A++ + S+ + + + + T + Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611 Query: 646 QAQVVTTVVGGVTKTITLVKSPISVPGGSALI-SNLGKVMSVVQTKPVQTSAVTGQASTG 704 +A V + +P P + S+L + + + A QAS G Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671 Query: 705 PVTQIIQTKGPLPAGTILKLVTSADG-KPTTIITTTQASGAGTKPTILGISSVSPS-TTK 762 + KGP T LK V A + T IIT G TK + + P + K Sbjct: 1672 ----LPAKKGP----TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723 Query: 763 PGTTTIIKTIPMSAII-----TQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITA 817 G+ + T+ + ++ + A G +S K P+ +K T T A + + Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP 1783 Query: 818 VPKIAT 823 P+ A+ Sbjct: 1784 KPESAS 1789 Score = 45.1 bits (105), Expect = 7e-04 Identities = 52/207 (25%), Positives = 80/207 (38%), Gaps = 27/207 (13%) Query: 402 IPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTI 461 +P+ T PTP P+ P S A++ PAV P T G P+ PP T+ Sbjct: 1555 VPSPKKTPAIPTPKEAPATP-----SSKEASSPPAVTPSTYKGAP-SPKELLIPPAVTSP 1608 Query: 462 QVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521 +++ P+ + PA P+ T +P VT + +P +VT Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPA------PKGTPTSPPVTPSSLKDSPTSPASVT---C 1659 Query: 522 GVRMVVPTQSAQGTVIGSSPQMSGMAAL--AAAAAATQKIPPSSAPTVLSVPAGTTIVKT 579 + VP Q+++G P G AL A A + P +APT G K+ Sbjct: 1660 KMGATVP-QASKGL-----PAKKGPTALKEVLVAPAPESTPIITAPT----RKGPQTKKS 1709 Query: 580 MAVTPGTTTLPATVKVASSPVMVSNPA 606 A +P P+ + P+ PA Sbjct: 1710 SATSPPICPDPSAKNGSKGPLSTVAPA 1736 Score = 32.0 bits (71), Expect = 6.3 Identities = 54/231 (23%), Positives = 80/231 (34%), Gaps = 40/231 (17%) Query: 399 KYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPL---------TQVGITLLP 449 K P TAA P P + + P P AP+ P + G+ L Sbjct: 1768 KASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLES 1827 Query: 450 QAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP--AVLKVTGPQATTGTPLVTMRPAS 507 + P P ++LP +P IS GVP +VL + G P+ T Sbjct: 1828 PSKPLAPADED-ELLPLIPPEPIS-------GGVPFQSVLVNMPTPKSAGIPVPT----- 1874 Query: 508 QAGKAPVTVTSLPAGVRM----VVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSS 563 + K PVT + +G VP Q S Q + A AAAA + P S Sbjct: 1875 PSAKQPVTKNNKGSGTESDSDESVPELEEQ-----DSTQATTQQAQLAAAAEIDEEPVSK 1929 Query: 564 APTVLSVPAGTTIVKTMAVTPGTTTLPATVK-------VASSPVMVSNPAT 607 A S + + + T T++ V + P + +PA+ Sbjct: 1930 AKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPAS 1980 >gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] Length = 1486 Score = 118 bits (295), Expect = 7e-26 Identities = 251/1154 (21%), Positives = 413/1154 (35%), Gaps = 200/1154 (17%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 P ++ T+T+PT V PP +A V P + + IT+ + P TT Q Sbjct: 95 PVSSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTSFI-ITI---SHPTSICVTTTQ 150 Query: 463 VLPT-----VPGSSISVPTAARTQGVPAVLKVTG-----PQATTG--TPLVTMRPASQAG 510 V T P + V T T + K T P TT TP+VT+ P+S + Sbjct: 151 VAFTSSYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPSSVSA 210 Query: 511 KAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSV 570 T++ + R T G++ ++ L A +T Sbjct: 211 TDTTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLKTAVTSTS------------- 257 Query: 571 PAGTTIVKTMAVTPGTTTL--PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTS 628 P ++I T VT TTT P SSP TR + ++ + T ++ T+ Sbjct: 258 PITSSITSTNTVTSMTTTASQPTATNTLSSP-------TRTILSSTPVLSTETITSGITN 310 Query: 629 TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQ 688 T P+ T+ + T+++ T + T T+ S + +++ L S+ Sbjct: 311 TTPLSTLVTTLPTTISRSTPTSETTYP-TSPTSTVTDSTTKIAYSTSMTGTLSTETSL-- 367 Query: 689 TKPVQTSAVTGQASTGPVTQIIQTKGPLPA--------GTILKLVTS-ADGKPTTIITTT 739 P +S T + +T P+T ++ T + + TI VTS + + T+ ITTT Sbjct: 368 -PPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTT 426 Query: 740 Q----------ASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSS 789 + +S TK T S SPS T TTT + + + T TS Sbjct: 427 ETPSHSTPRFTSSFTNTKTT----SHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSH 482 Query: 790 PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPG 843 +I TT+ + T + IT H T+ P Sbjct: 483 SARSFTSSITTTETTSHNTRSFTSSITTTE--TNSHSTTSFTSSITTTETTSHSTPSFSS 540 Query: 844 TI------LRTVPMGGVRLVTPVTVSAVKPAVTTLVVK------GTTGVTTLGTVTGTVS 891 +I L + P + T T S + P +T+ + T G T+ T T T S Sbjct: 541 SITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTS 600 Query: 892 TSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITM 951 S + ++++T T + + T S + PT +T S+ T + TT T+ Sbjct: 601 ESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIP-----TTSLRTL 655 Query: 952 QPVSQPTQVTLITA------PSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQ 1005 P S T +L T P+ + P I++S + Q T T ++ + + Sbjct: 656 TPSSVGTSTSLTTTTDFPSIPTDISTLPTR---THIISSSPSIQSTETSSLVGTTSPTMS 712 Query: 1006 PGTVTL-VCSNPPCETHETGT-----TNTATTTVVANLGG---HPQPTQVQFVCDRQEAA 1056 +TL + N P + T T T T V+ + G P PT V F + Sbjct: 713 TVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTSPAPTTVTFG-STDSST 771 Query: 1057 ASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGT 1116 ++L T T ++V P TH + T +T P +T T T Sbjct: 772 STLHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPST-------------PSLQTSLTST 818 Query: 1117 TNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATST 1176 + T + + R S +T A+ + T S+ Sbjct: 819 SEFTTESFT----------------------RGSTSTNAI---------LTSFSTIIWSS 847 Query: 1177 TMTVMATGAPCSAG--PLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 T T++ + +P SA P+ ++ P SP + S + S SI P+ S Sbjct: 848 TPTIIMSSSPSSASITPVFSTTIHSVPS--SPY------IFSTENVGSASITGFPSLSSS 899 Query: 1235 HAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPC 1294 ST++ T SS+ + P PSTT + + P A+ T C Sbjct: 900 ATTSTSS-TSSSLTTALTEITPFSYI---SLPSTTPCPGTITITIVP-ASPTDPCVEMDP 954 Query: 1295 ETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAG 1354 T T T T + + V T TT+ T++ P + Sbjct: 955 STEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSS------------MMPESE 1002 Query: 1355 RPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQ 1414 + ++STGT T TV + + P+ + + P P Sbjct: 1003 SSISPNASSSTGT------------GTVPTNTVFTSTRL---PTSETWLSNSSVIPLPLP 1047 Query: 1415 RVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITT 1474 V + P T + ++ TS+ S++ PP + + V +TQ + T +S TT Sbjct: 1048 GVSTIPL--TMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPT---TLTSRRTT 1102 Query: 1475 TVSSTLTRAVTTVT 1488 ++S +T T T Sbjct: 1103 RITSQMTTQSTLTT 1116 Score = 103 bits (256), Expect = 2e-21 Identities = 253/1119 (22%), Positives = 411/1119 (36%), Gaps = 196/1119 (17%) Query: 437 VQPLTQVGITLLPQAAP-APPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQAT 495 +Q L +G+ + +A+P A T +T +SIS R + AVL P + Sbjct: 1 MQLLGLLGLLWMLKASPWATGTLST--------ATSISQVPFPRAEAASAVLS-NSPHSR 51 Query: 496 --TGTPLVTMRPASQAG----KAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMA-- 547 G PL + AS A AP+T+T+ P + ++ + S+ S A Sbjct: 52 DLAGWPLGVPQLASPAPGHRENAPMTLTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFK 111 Query: 548 ------ALAAAAAATQKIPPSSAPTVLSVPAGTTIVKT-MAVTPGTTTLPATVKVASSPV 600 + +A T+ + P+S +S P + T +A T T+ P T K ++ Sbjct: 112 VETTPPTVLVYSATTECVYPTSFIITISHPTSICVTTTQVAFTSSYTSTPVTQKPVTTVT 171 Query: 601 MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT 660 + T T+A TS S T PI+TV S +V+ T + T+T Sbjct: 172 STYSMTTTEKGTSAM---TSSPSTTTARETPIVTVTPS---SVSATDTTFHTTISSTTRT 225 Query: 661 ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720 P G + + PV T+ T ST P+T I + T Sbjct: 226 TERTPLPT------------GSIHTTTSPTPVFTTLKTAVTSTSPITSSITS-----TNT 268 Query: 721 ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780 + + T+A +PT T T +S PT +SS +T+ T+ I T P+S ++T Sbjct: 269 VTSMTTTAS-QPTA--TNTLSS-----PTRTILSSTPVLSTETITSGITNTTPLSTLVTT 320 Query: 781 AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG 840 T S+P T T T + + + KIA + Sbjct: 321 LPTTISRSTP----------TSETTYPTSPTSTVTDSTTKIAY--------------STS 356 Query: 841 QPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH 900 GT+ + P T +A P T +V TT +++ T + + ST + H Sbjct: 357 MTGTLSTETSLPPTSSSLPTTETATTP--MTNLVTTTTEISSHSTPSFSSSTIYSTVTSH 414 Query: 901 STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960 ST + ITT T + + + + T + + + + +TT T S P+ Sbjct: 415 ST-PRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSH--STPSFT 471 Query: 961 TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET 1020 + IT + + SI + TT T + T + + T + S ET Sbjct: 472 SSITT-TETTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTET 530 Query: 1021 --HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNP 1078 H T + +++ TT L H P +V + S +T + + + Sbjct: 531 TSHSTPSFSSSITTTETPL--HSTPGLTSWVTTTK--TTSHITPGLTSSITTTETTSHST 586 Query: 1079 PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRA 1138 P T TT T + +T +++ S T +T+TTA++S H + A Sbjct: 587 PGFTSSITTTETTSESTPSLSSSTIYS----------TVSTSTTAITS----HFTTSETA 632 Query: 1139 CAAG--TPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPS 1196 TP+ + + T +L T + TST++T PS Sbjct: 633 VTPTPVTPSSLSTDIPTTSLRTL--------TPSSVGTSTSLTTTTD----------FPS 674 Query: 1197 MAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAP 1256 + P + P + + SSPSI+ + T S VG P M+ Sbjct: 675 I--------PTDISTLPTRTHIISSSPSIQ-------------STETSSLVGTTSPTMST 713 Query: 1257 VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNT--ATTSNAGSAQ 1314 V +L+ + +T ++ + ++ P T TQ PP T TGT + TT GS Sbjct: 714 VRMTLR-ITENTPISSFSTSIVVIPE-TPTQ---TPPVLTSATGTQTSPAPTTVTFGSTD 768 Query: 1315 RVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVG 1374 T T HT T +T+ Q P T QTT + ++ S+ Sbjct: 769 ----------SSTSTLHTLTPSTALSTI--VSTSQVPIPSTHSSTLQTTPSTPSLQTSL- 815 Query: 1375 ALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT 1434 ++S T ES + + + A+L F T S P + ++ + T Sbjct: 816 -----TSTSEFTTESFTRGSTSTN-------AILTSFSTIIWSSTPTIIMSSSPSSASIT 863 Query: 1435 TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTT--VSSTLTRAVTTVT---- 1488 V S + P V S SSSA T+T SS+LT A+T +T Sbjct: 864 PVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSY 923 Query: 1489 ----QSTPVPG-------PSVPPPEELQVSPGPRQQLPP 1516 +TP PG P+ P +++ P PP Sbjct: 924 ISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPP 962 Score = 86.3 bits (212), Expect = 3e-16 Identities = 182/790 (23%), Positives = 283/790 (35%), Gaps = 96/790 (12%) Query: 858 TPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIA 917 TP TV + TT V T+ + T+ T T+ A TS+ +TP+T Sbjct: 115 TPPTVLVY--SATTECVYPTSFIITISHPTSICVTTTQVA---FTSSYTSTPVTQKPVTT 169 Query: 918 TLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDL 977 S+ + T SA ++ + TP +T+ P S T + Sbjct: 170 VTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPSSVSATDTTFHTTISSTTRTTERT 229 Query: 978 PVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANL 1037 P+ + TT PT T + P T ++ +N T + TAT T+ + Sbjct: 230 PLPTGSIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPT 289 Query: 1038 GGHPQPTQVQFVCDRQEAAASLVTST------VGQQNGSVVRVCSNPPCE-THETGTTNT 1090 T V E S +T+T V ++ R S P E T+ T T+T Sbjct: 290 RTILSSTPVL----STETITSGITNTTPLSTLVTTLPTTISR--STPTSETTYPTSPTST 343 Query: 1091 ATTATSNMAGQHGCSNP-------PCETHETGTTNTATTAMSSVGANHQRDARRACAAGT 1143 T +T+ +A + P + TT TATT M+++ + + + + Sbjct: 344 VTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFS 403 Query: 1144 PAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM--AREP 1201 + I +V S R TS+ +TT T P + P S + Sbjct: 404 SSTIYSTVT-----------SHSTPRFTSSITTTET------PSHSTPRFTSSFTNTKTT 446 Query: 1202 GGRSPAFVQLAPLSSKVRLSSP----SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257 RSP+F L + S+P SI HS T+++T + + R Sbjct: 447 SHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFT- 505 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCS-NPPCETHETGTTNTATTSNAGSAQRV 1316 S +TT T + S T T+ S + P + TT T S G V Sbjct: 506 ------SSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWV 559 Query: 1317 CSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGAL 1376 T T+H TS+ T + P T +TTS +T S+S + Sbjct: 560 -------TTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTSE-STPSLSSSTI 611 Query: 1377 LPDATSSHRTVESGLEVA-AAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATT 1435 ++S + S + A + TP ++L PT + + P GT+ + TT Sbjct: 612 YSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTP---SSVGTSTSLTT 668 Query: 1436 VTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPG 1495 T S D + + S+ TSS TT+ + + R +T++TP+ Sbjct: 669 TTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISS 728 Query: 1496 PSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEP 1555 S + V P Q PP +L SA + +QT P V ST Sbjct: 729 FST----SIVVIPETPTQTPP--VLTSA------------TGTQTSPAPTTVTFGSTDSS 770 Query: 1556 SS-----GQESAGSAVVATVVVQPPPPTQSEVDQL--SLP--QELMAEAQAGTTTLMVTG 1606 +S +A S +V+T V P P T S Q S P Q + TT G Sbjct: 771 TSTLHTLTPSTALSTIVSTSQV-PIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRG 829 Query: 1607 LTPEELAVTA 1616 T +T+ Sbjct: 830 STSTNAILTS 839 Score = 85.9 bits (211), Expect = 4e-16 Identities = 153/661 (23%), Positives = 250/661 (37%), Gaps = 75/661 (11%) Query: 405 TAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQP-LTQVGITLLPQAAPAPPTTTTIQV 463 ++ T T T + PS ++ + P + P + +T T TTT Sbjct: 523 SSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETT 582 Query: 464 LPTVPGSSISVPTAART-QGVPAVLKVT--GPQATTGTPLVTMRPASQAGKAPVTVTSLP 520 + PG + S+ T T + P++ T +T+ T + + S+ P VT P Sbjct: 583 SHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVT--P 640 Query: 521 AGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLS-VPAGTTIVKT 579 + + +PT S + T+ SS + + T P S PT +S +P T I+ + Sbjct: 641 SSLSTDIPTTSLR-TLTPSS------VGTSTSLTTTTDFP--SIPTDISTLPTRTHIISS 691 Query: 580 MAVTPGTTT--LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHK 637 T T L T S V ++ T ++ V T T T P++T Sbjct: 692 SPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLT--- 748 Query: 638 SGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAV 697 + T Q + TTV G T + T ++ + L ++S Q T + Sbjct: 749 --SATGTQTSPAPTTVTFGSTDSSTSTLHTLTPS------TALSTIVSTSQVPIPSTHSS 800 Query: 698 TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVS 757 T Q T P T +QT + + T I+T+ + PTI+ SS S Sbjct: 801 TLQ--TTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPS 858 Query: 758 PSTTKPGTTTIIKTIPMSAII---TQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKI 814 ++ P +T I ++P S I G+ +T P + S T T+ +S T A +I Sbjct: 859 SASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEI 918 Query: 815 ITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVV 874 P ++ T P G +T V S P V + Sbjct: 919 -----------------------TPFSYISLPSTTPCPGTITITIVPASPTDPCVE---M 952 Query: 875 KGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAA 934 +T T+ T TV TS S+ T +TT + T S + ++I+ +A+ Sbjct: 953 DPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTY--MDTSSMMPESESSISPNAS 1010 Query: 935 QTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPV-SILASPTTEQPTAT 993 +T T T PT T+ T L T+ + + V LP+ + P T +P+++ Sbjct: 1011 SSTGTG----TVPTNTVF-----TSTRLPTSETWLSNSSVIPLPLPGVSTIPLTMKPSSS 1061 Query: 994 V-TIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTA--TTTVVANLGGHPQPTQVQFVC 1050 + TI + P T S P T +T TT T+ TT + + + T C Sbjct: 1062 LPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMTTQSTLTTTAGTC 1121 Query: 1051 D 1051 D Sbjct: 1122 D 1122 Score = 63.9 bits (154), Expect = 2e-09 Identities = 151/702 (21%), Positives = 247/702 (35%), Gaps = 94/702 (13%) Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE-PGGRSPAFVQ 1210 ATG L A S SQ + A S ++ + PL P +A PG R A + Sbjct: 19 ATGTLSTAT-SISQVPFPRAEAASAVLSNSPHSRDLAGWPLGVPQLASPAPGHRENAPMT 77 Query: 1211 LAP-----LSSKVRLSSP---SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQ 1262 L L S+ L+SP + P + + V T T A + P + Sbjct: 78 LTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTSFIIT 137 Query: 1263 GGSPSTTVTVTALEALLCPSATVTQVCSNP--------PCETHETGT---TNTATTSNAG 1311 P T++ VT + S T T V P T E GT T++ +T+ A Sbjct: 138 ISHP-TSICVTTTQVAFTSSYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTAR 196 Query: 1312 SAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSV 1371 V P + T HT ++T+ P P G T T TT+ Sbjct: 197 ETPIVTVTPSSVSATDTTFHTTISSTTRTTERTPL-----PTGSIHTTTSPTPVFTTLKT 251 Query: 1372 SVGALLPDATS--SHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGT 1429 +V + P +S S TV S A+ P+ T + PT+ + S+ P + ET T Sbjct: 252 AVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSS------PTRTILSSTPVLSTETIT 305 Query: 1430 TH-TATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVT 1488 + T TT S + + + S TS + T+ +ST+T + T + Sbjct: 306 SGITNTTPLSTLVTTLPTTISRSTP-------------TSETTYPTSPTSTVTDSTTKIA 352 Query: 1489 QSTPVPGP-----SVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543 ST + G S+PP LP + + T L+ + E+ S S TP Sbjct: 353 YSTSMTGTLSTETSLPPTSS---------SLPTTETATTPMTNLVTTTTEISSHS-TPSF 402 Query: 1544 PAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLM 1603 ++ S+ S+ + ++ T P T S + + + TTT Sbjct: 403 SSSTIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTET 462 Query: 1604 VTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMG-----TGEPMDTSEA 1658 + TP + E + +A + + + + T TS Sbjct: 463 TSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFT 522 Query: 1659 AATVTQAELGHLSAEGQEGQATT-IPI---------VLTQQELAALVQQQQLQEAQAQQQ 1708 ++ T H + TT P+ V T + + + + Sbjct: 523 SSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETT 582 Query: 1709 HHHLP--TEALAPADSLND--PAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAP 1764 H P T ++ ++ ++ P++ S+ T+ STV+ + T S T V P Sbjct: 583 SHSTPGFTSSITTTETTSESTPSLSSS-------TIYSTVSTSTTAITSHFTTSETAVTP 635 Query: 1765 QPVV---VASPAKLQAAATLTEVANGIE-SLGVKPDLPPPPS 1802 PV +++ + TLT + G SL D P P+ Sbjct: 636 TPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPT 677 Score = 52.8 bits (125), Expect = 3e-06 Identities = 73/371 (19%), Positives = 136/371 (36%), Gaps = 79/371 (21%) Query: 361 TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV 420 T+ P P V ++++ + +TA S ++ + IP+T ++ TP+ PS+ Sbjct: 753 TQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPS-TPSL 811 Query: 421 PAN--------------------------------------PPKSPAPAAAAP------- 435 + SP+ A+ P Sbjct: 812 QTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIH 871 Query: 436 ---------AVQPLTQVGITLLPQAAPAPPTTT-------TIQVLPTVPGSSISVPTAAR 479 + + + IT P + + T+T T + P S IS+P+ Sbjct: 872 SVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLPS--- 928 Query: 480 TQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVT-VTSLPAGVRMV-----VPTQSAQ 533 T P + +T A+ P V M P+++A P T +T P MV + Q+ Sbjct: 929 TTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTL 988 Query: 534 GTVIGSSPQM----SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAV----TPG 585 T + +S M S ++ A+++ T +P ++ T +P T + +V PG Sbjct: 989 TTYMDTSSMMPESESSISPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPG 1048 Query: 586 TTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQ 645 +T+P T+K +SS + +++ + TS + T T +T ++ +T Sbjct: 1049 VSTIPLTMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQM 1108 Query: 646 QAQVVTTVVGG 656 Q T G Sbjct: 1109 TTQSTLTTTAG 1119 >gi|16945972 kelch domain containing 3 [Homo sapiens] Length = 382 Score = 114 bits (284), Expect = 1e-24 Identities = 84/269 (31%), Positives = 128/269 (47%), Gaps = 24/269 (8%) Query: 15 LQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGN--EGIVDELHVYNTATNQWFIP 72 L P + G + VP R+GH V I + ++++GG N EG + L+ ++ T++WF P Sbjct: 59 LPPVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTP 118 Query: 73 AVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGK-YSNDLYELQASRWEWKRLKAKTPKNG 131 V G +P + G + +FGG + +SND+++L S W + K G Sbjct: 119 RVSGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTK----G 174 Query: 132 PPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAW-DIP 190 P R HS +++G+ Y+FGG A+ +N Y N + + + R AW D P Sbjct: 175 SPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTR----TEAWLDCP 230 Query: 191 ITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLG----DLWTLDIDTLTWNKPS 246 T VLP R SH+A Y +L I+GG + RL DLW + + TW K Sbjct: 231 PT-PVLPEGRRSHSAFGYN------GELYIFGGYNA-RLNRHFHDLWKFNPVSFTWKKIE 282 Query: 247 LSGVAPLPRSLHSATTIGNKMYVFGGWVP 275 G P PR +G+K+ +FGG P Sbjct: 283 PKGKGPCPRRRQCCCIVGDKIVLFGGTSP 311 Score = 73.2 bits (178), Expect = 2e-12 Identities = 80/281 (28%), Positives = 106/281 (37%), Gaps = 42/281 (14%) Query: 88 VCDGTRLLVFGGMVEYGKYSN----DLYELQASRWEWKRLK-AKTPKNGPPPCP---RLG 139 V G R+ FGG Y D++ A W +L K+ G P R G Sbjct: 20 VAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRGQAPVVPYMRYG 79 Query: 140 HSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPP 199 HS L+ + L+GG ND+E N LY ++ W P G +P Sbjct: 80 HSTVLIDDTVLLWGG-RNDTEGA-------CNVLYAFDVNTHK----WFTPRVSGTVPGA 127 Query: 200 RESHTAVVYTEKDNKKSKLVIYGG---MSGCRLGDLWTLDIDTLTWNKPSLSGVAPLPRS 256 R+ H+A V + + I+GG + C D+ LD T+TW G R Sbjct: 128 RDGHSACVLGKI------MYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRD 181 Query: 257 LHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLED 316 HSAT +G+ MYVFGG D H N + + T AW L Sbjct: 182 FHSATMLGSHMYVFGG-----RADRFGPFHSNNEIYCNRIRVFDTRTEAW---LDCPPTP 233 Query: 317 NIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLW 357 +P R H A N LYI+ GY N DLW Sbjct: 234 VLPEGRRSHSAFGYNGELYIFG---GYNARLNRHF--HDLW 269 Score = 65.1 bits (157), Expect = 7e-10 Identities = 63/248 (25%), Positives = 106/248 (42%), Gaps = 45/248 (18%) Query: 137 RLGHSFSLVGNKCYLFGGLAN--DSEDPKNNIPRYLN--DLYILELRPGSGVVAWDIPIT 192 R+ H+ VG++ Y FGG + D E + N L +L P + P Sbjct: 14 RVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRGQAP-- 71 Query: 193 YGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMS----GCRLGDLWTLDIDTLTWNKPSLS 248 V+P R H+ V+ + ++++GG + C + L+ D++T W P +S Sbjct: 72 --VVPYMRYGHSTVLIDD------TVLLWGGRNDTEGACNV--LYAFDVNTHKWFTPRVS 121 Query: 249 GVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKC-TNTLACLNLDTMAWE 307 G P R HSA +G MY+FGG +E++ C +N + L+ TM W Sbjct: 122 GTVPGARDGHSACVLGKIMYIFGG-------------YEQQADCFSNDIHKLDTSTMTWT 168 Query: 308 TILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAW--NNQVCCKDLWYLET---- 361 I + + R R H A + + +Y++ GR + NN++ C + +T Sbjct: 169 LI---CTKGSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEA 225 Query: 362 --EKPPPP 367 + PP P Sbjct: 226 WLDCPPTP 233 Score = 57.0 bits (136), Expect = 2e-07 Identities = 44/167 (26%), Positives = 72/167 (43%), Gaps = 17/167 (10%) Query: 27 GPVPRPRHGHRAVAIKELIVVFGG----------GNEGIVDELHVYNTATNQWFIPAVRG 76 G R R H A + + VFGG NE + + V++T T W Sbjct: 174 GSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTP 233 Query: 77 DIPPGCAAYGFVCDGTRLLVFGGM-VEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPC 135 +P G ++ L +FGG ++ +DL++ + WK+++ K G PC Sbjct: 234 VLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPK----GKGPC 289 Query: 136 PRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYL--NDLYILELRP 180 PR +VG+K LFGG + E+ + + +DL+IL+ P Sbjct: 290 PRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSP 336 >gi|239754668 PREDICTED: mucin 12 [Homo sapiens] Length = 1952 Score = 112 bits (280), Expect = 4e-24 Identities = 307/1365 (22%), Positives = 486/1365 (35%), Gaps = 230/1365 (16%) Query: 406 AATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLP 465 ++T P S P++ SPAP+ A V ++ ++P+ TT Sbjct: 331 SSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAF-----VKLSTTYHSSPSSTPTTHFSASS 385 Query: 466 TVPGSSI------SVPTAARTQGVPAVLKVTG--------------------PQATTGTP 499 T G S S P A T PA +G P+++T T Sbjct: 386 TTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST-TS 444 Query: 500 LVTMRPASQAGKAPVTVTSLPAGVRMVVPTQ------SAQGTVIGSSPQMSGMAALAAA- 552 + A+ G T +S P+ + T S + T S +SG + + A Sbjct: 445 GHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKAS 504 Query: 553 -----AAATQKIPPSSAPTVL-----SVPAGTTIVKTMAVTPGTTTLPATVKVA----SS 598 A AT +P S P+VL P + ++T A+ PG+TT P + + SS Sbjct: 505 HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL-PGSTTKPGLSEKSTTFYSS 563 Query: 599 PVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP--IITVHKSGTVTVAQQAQVVTTVVGG 656 P +P T L + G S S T+ S RP T G+ T+ +Q T Sbjct: 564 P---RSPDTTHLPASMTSSGVSEESTTSHS-RPGSTHTTAFPGSTTMPGLSQESTASHSS 619 Query: 657 VTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL 716 T T + SP GS S+LG + ++P T +T + +++ P+ Sbjct: 620 PGPTDTTL-SP-----GSTTASSLGPEYTTFHSRPGSTETTLLPDNT-TASGLLEASMPV 672 Query: 717 ------------PAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPG 764 PAG+ T+ G+ TT + ++ P + V PSTT G Sbjct: 673 HSSTRSPHTTLSPAGS-----TTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHG 727 Query: 765 TTTIIKTIPMSAIITQAG----ATGVTSSPGIKSPITIITTKVMTSGTG----------- 809 + + I T +SA T +G +T SSPG + + TSG G Sbjct: 728 SPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT-TSGRGEESTTSHSSTT 786 Query: 810 -----APAKIITAVPKIATGHGQQGVTQVV-LKGAPGQPGTILRTVPMGGVRLVTPVTVS 863 AP+ V + + H G T + G ++ + T V Sbjct: 787 HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVL 846 Query: 864 AVKPAVTTLVVKGTTGVTTLGTVTGTV---STSLAGAGGHSTS--ASLATPITTLGTIAT 918 + + L+ + TT + G++ T ST+ G ST+ +S +P TTL +T Sbjct: 847 PARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 906 Query: 919 LSSQVINPTAITVSAAQTTLTAA--GGLTTP-------TITMQPVSQPTQVTLITAPSGV 969 SS V + + S +T T A TTP T P S T + + + + Sbjct: 907 TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXL 966 Query: 970 EAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV---QPGTVTLVCSNPPCETHETGTT 1026 +P P+S ++ TT P +T T S + P + S P T +G + Sbjct: 967 VGEPTTS-PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS--PASTTSSGVS 1023 Query: 1027 NTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHET- 1085 +TT+ H +P T T + + S +H + Sbjct: 1024 EESTTS-------HSRPGS---------------THTTAFPGSTTMPGVSQESTASHSSP 1061 Query: 1086 GTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPA 1145 G+T+T + S A G P T +G +T TT + Sbjct: 1062 GSTDTTLSPRSTTASSLG---PESTTFHSGPGSTETTLLPD------------------- 1099 Query: 1146 VIRISVATGALEAAQGSKSQC-QTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGR 1204 + A+G LEA+ S R T + + + T + P +M P Sbjct: 1100 ---NTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTT 1156 Query: 1205 SPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGG 1264 S AFV+L+ S SPS +P S + +T + S +AP Sbjct: 1157 S-AFVELSTTSH----GSPS--SIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPAR 1209 Query: 1265 SPSTTVTVTALEALLCPSATVT------QVCSNPPCETHETGTTNTATTSNAGSAQRVCS 1318 S ++ + + P +T T S E+ + ++ T T S+ S Sbjct: 1210 STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 1269 Query: 1319 NPPCETHET----GTTHTATTATSNGGTGQPEGGQQPPAGR---PCETHQTTS----TGT 1367 P H + TTH ++T++G + + P P H TTS T Sbjct: 1270 EEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAEST 1329 Query: 1368 TMSVSVGALLPDATSSHRT--VESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425 T +S G++ S+ T + + + + S +P T A + + P Sbjct: 1330 TFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQ-TLSPASMTSSSISGEPTSLYS 1388 Query: 1426 ETGTTHT----ATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAIT-TTVSSTL 1480 + +THT A+T TS +S Q+ S G E+T TSS A TT S Sbjct: 1389 QAESTHTTAFPASTTTSGLS--QESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQP 1446 Query: 1481 TRAVTTVT-QSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQ 1539 A++TV+ ST VPG S SPG + S S + S + Sbjct: 1447 GSALSTVSPASTTVPGLS-EESTTFYSSPGSTE-----TTAFSHSNTMSIHSQQSTPFPD 1500 Query: 1540 TP-----ELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAE 1594 +P LPA + + G+ S+ S+ A T P P + D + P Sbjct: 1501 SPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTT----PLPARSTASDLVGEPTTFYIS 1556 Query: 1595 AQAGTTTLM-----VTGLTPEELAVTAAAEAAAQAAATEEAQALA 1634 TTL +GLT E + + +TE + LA Sbjct: 1557 PSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLA 1601 Score = 92.0 bits (227), Expect = 5e-18 Identities = 269/1325 (20%), Positives = 460/1325 (34%), Gaps = 162/1325 (12%) Query: 435 PAVQPLTQVGI--TLLPQA---APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV 489 P P+T + T LP + A +TT P P ++S P + GV Sbjct: 173 PKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLS-PARTTSSGVSEKSTT 231 Query: 490 T----GPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS--PQM 543 + GP T P T P + S+P T + GT SS P+ Sbjct: 232 SHSRPGPTHTIAFPDSTTMPG--VSQESTASHSIPGST----DTTLSPGTTTPSSLGPES 285 Query: 544 SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVS 603 + + + T ++P ++ T + +T V + +P TT PA SS Sbjct: 286 TTFHS-SPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPA-----SSTTHEG 337 Query: 604 NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITL 663 P T ++ + S T+ + T H S + T +T +G ++ + Sbjct: 338 EPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV 397 Query: 664 VKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILK 723 SP+ + T P SA +G + P T+ Sbjct: 398 HSSPV----------------ATATTPPPARSATSGHVEESTAYH----RSPGSTQTMHF 437 Query: 724 LVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGA 783 +S + T S TK + ++ T+ + +T T +G Sbjct: 438 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 497 Query: 784 TGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK-IATGHGQQGVTQVVLKGAPGQP 842 + S SP + TT V+ +G+ + + P I++G + L G+ +P Sbjct: 498 S-EESKASHSSPDAMATT-VLPAGSTPSVLVGDSTPSPISSG----SMETTALPGSTTKP 551 Query: 843 GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHST 902 G ++ T S P T L +T+ G + ++ H+T Sbjct: 552 GLSEKS---------TTFYSSPRSPDTTHL----PASMTSSGVSEESTTSHSRPGSTHTT 598 Query: 903 SASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTL 962 + +T + L +T S PT T+S TT ++ G T T +P S T+ TL Sbjct: 599 AFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYT-TFHSRPGS--TETTL 655 Query: 963 I---TAPSGV--EAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPP 1017 + T SG+ + PVH +T P T++ A S + G T S P Sbjct: 656 LPDNTTASGLLEASMPVHS---------STRSPHTTLSPAGS---TTRQGESTTFHSWPS 703 Query: 1018 CETHETGTTNTATTTVVANLGGHPQPTQV--QFVCDRQEAAASLVTSTVGQQNGSVVRVC 1075 T + V + H P+ + + R + + ST + + Sbjct: 704 SNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 763 Query: 1076 SNPPCET-----HETGTTNTATTATSNMA------------GQHGCSNPPCETHETGTTN 1118 P +T E+ T++++TT T + A H TH ++ Sbjct: 764 HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 823 Query: 1119 TATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTM 1178 T+ + S+ ++ +DA PA SV G + S +T ++TT Sbjct: 824 TSGRSEESIASHSSQDATGTIV--LPARSTNSVLLGESTTSPISSGSMETTALPGSTTTP 881 Query: 1179 TVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVS 1238 + + P P+ P + + V +S R S P + +S Sbjct: 882 GLSERSTTFHSSP-RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS 940 Query: 1239 TAAMT-RSSVGAGEPRMAPVCES--LQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCE 1295 + T SS G+ + + P + L G ++ ++ + E P +T T S Sbjct: 941 RHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 1000 Query: 1296 THETGTTNTATTSNAGSAQRVCSNPPCETH-ETGTTHTATTATSNGGTGQPEGGQQPPAG 1354 + + + T S A + S +H G+THT G T P Q+ A Sbjct: 1001 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP---GSTTMPGVSQESTAS 1057 Query: 1355 R--PCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTP-----QAGTAL 1407 P T T S +T + S+G P++T+ H + E P T +A T + Sbjct: 1058 HSSPGSTDTTLSPRSTTASSLG---PESTTFH-SGPGSTETTLLPDNTTASGLLEASTPV 1113 Query: 1408 LAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVEST---QGDSV 1464 + + R +P T G + T + S+ + PP S E+ +T S+ Sbjct: 1114 HSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSI 1173 Query: 1465 NITSSSAITTTV----SSTLTRAVTTVTQSTPVPGPS-----VPPPEELQVSPGPRQQLP 1515 T SA +TT ST + +TP P S V SPG Q + Sbjct: 1174 PTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTM- 1232 Query: 1516 PRQLLQSASTALMGESAEVLSASQTPEL--PAAVDLSSTGEPSSGQESAGSAVVATVVVQ 1573 +S++ + E + +S T + P + + EP+S S GS Sbjct: 1233 --HFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPES 1290 Query: 1574 PPPPTQSEVDQLS-----------LPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA-- 1620 +SE S LP + +T ++P + T A+ A Sbjct: 1291 STTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFY--ISPGSMETTLASTATT 1348 Query: 1621 ---AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDT-SEAAATVTQAELGHLSAEGQE 1676 +A++ + Q + A+ + +GEP S+A +T T A + G Sbjct: 1349 PGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLS 1408 Query: 1677 GQATT 1681 ++TT Sbjct: 1409 QESTT 1413 Score = 85.1 bits (209), Expect = 6e-16 Identities = 266/1278 (20%), Positives = 433/1278 (33%), Gaps = 157/1278 (12%) Query: 594 KVASSPVMVSNPATRMLKTAAAQ---------VGTSVSSATNTSTRPIITVHKSGTVTVA 644 +V+SSP + AT+ +T G++V+++ +T T S T Sbjct: 54 EVSSSPDVSELTATKHEETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTF 113 Query: 645 QQAQVVTTVVGGVTKTITLVKSPI-SVPGGSALISNLGKVMSVVQTKPVQ--TSAVTGQA 701 V T + G T T + S S + +S+ G + P TS G+ Sbjct: 114 SDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEP 173 Query: 702 STGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTT 761 T P+T LP T K TT ++ ++ P S VS +T Sbjct: 174 KTSPITSASMETTALPGST---TTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKST 230 Query: 762 ----KPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITA 817 +PG T I A GV+ I T ++ GT P+ + Sbjct: 231 TSHSRPGPTHTI------AFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSL--- 281 Query: 818 VPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGT 877 P+ T H G T+ T G + TPV S P T T Sbjct: 282 GPESTTFHSSPGYTKTTRLPD--------NTTTSGLLEASTPVHSSTGSPHTTLSPASST 333 Query: 878 T---GVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAA 934 T TT + + TS A +G S L+T T S + SA+ Sbjct: 334 THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLST---------TYHSSPSSTPTTHFSAS 384 Query: 935 QTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSG--VEAQPVHDLPVSILASPTTEQPTA 992 TTL +TP + + T +A SG E+ H P S + T P + Sbjct: 385 STTL-GHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGS---TQTMHFPES 440 Query: 993 TVTIADSGQGDVQPGTVTLVCSNPPCET---------HETGTTNTATTTVVANLGGHPQP 1043 + T S + G+ T S+ P T G+T T + + G + Sbjct: 441 STTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEE 500 Query: 1044 TQVQFVCDRQEA-----AASLVTSTVGQQNGSVVRVCSNP----PCETHETGTTNTATTA 1094 ++ A A S + VG S + S P T + G + +TT Sbjct: 501 SKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTF 560 Query: 1095 TSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQR-----------DARRACAAGT 1143 S+ ++ P +G + +TT+ S G+ H + + Sbjct: 561 YSSPRSP-DTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 619 Query: 1144 PAVIRISVATGALEAAQ-GSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPG 1202 P +++ G+ A+ G + + +T TT+ T +A LL SM Sbjct: 620 PGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNT----TASGLLEASMPVHSS 675 Query: 1203 GRSPAFVQLAPLSSKVRL-SSPSIKDLPAGRHSH----AVSTAAMTRSSVGAGEPRMAPV 1257 RSP L+P S R S + P+ + ++A + S+ G P P Sbjct: 676 TRSP-HTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 734 Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCET-----HETGTTNTATTSNAGS 1312 + STT + S TQ P +T E+ T++++TT S Sbjct: 735 THI---SARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS 791 Query: 1313 AQRVCS---NPPCETH----ETGTTHTATTATSNGGTGQ--PEGGQQPPAGRPCETHQTT 1363 A S P H T TTH ++T++G + + Q G ++T Sbjct: 792 APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARST 851 Query: 1364 ST-----GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPT--QRV 1416 ++ TT +S G++ A T E + +P++ L+P T V Sbjct: 852 NSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV 911 Query: 1417 CSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTT- 1475 G+THT S + P S + S + T A TTT Sbjct: 912 SEESTTSHSRPGSTHTTAFPDSTTT------PGLSRHSTTSHSSPGSTDTTLLPASTTTX 965 Query: 1476 -VSSTLTRAVTT-VTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAE 1533 V T +++ T++T +PG + + + P L AST G S E Sbjct: 966 LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 1025 Query: 1534 VLS------ASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSL 1587 + ++ T P + + + S+ S+ + T + P T S + Sbjct: 1026 STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT--LSPRSTTASSLG---- 1079 Query: 1588 PQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVM 1647 P+ + G+T T L P+ + EA+ ++ + + +Q Sbjct: 1080 PESTTFHSGPGSTE---TTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGES 1136 Query: 1648 GTGE----PMDTSEAAATVTQA--ELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQ 1701 T + DT A T T A EL S G ++IP T A+ + + Sbjct: 1137 TTFQSWPSSKDTMPAPPTTTSAFVELSTTS----HGSPSSIP---TTHFSASSTTFGRSE 1189 Query: 1702 EAQAQQQHHHLPTEALAPADSLNDPAI-ESNCLNELAGTVPSTVALLPSTATESLAPSNT 1760 E+ P +PA S + ES + G+ + STA+ S T Sbjct: 1190 ESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1249 Query: 1761 FVAPQPVVVASPAKLQAA 1778 + ++SP +A Sbjct: 1250 SHSSTTHTISSPPSTTSA 1267 >gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] Length = 2639 Score = 106 bits (264), Expect = 3e-22 Identities = 141/560 (25%), Positives = 192/560 (34%), Gaps = 100/560 (17%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462 P T T +PTP P + +P P V P T P P TTTT+ Sbjct: 1315 PITTTTTVTPTPTPT----STQSTTPTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVT 1369 Query: 463 VLPTVPGSSISVPT-AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521 PT G+ T T V TG Q T TP+ T VT T P Sbjct: 1370 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITT--------TTTVTPTPTPT 1421 Query: 522 GVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580 G + T T + +P +G A A T + P+ PT P T I T Sbjct: 1422 GTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTT 1481 Query: 581 AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGT 640 VTP T P P + T T + T T T IT Sbjct: 1482 TVTPTPT-----------PTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPIT------ 1524 Query: 641 VTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ 700 TT T T T ++P P + + P T T Sbjct: 1525 ----------TTTTVTPTPTPTGTQTPTPTP-----------ISTTTTVTPTPTPTGTQT 1563 Query: 701 ASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPS 759 +T P+T T P P GT PTT++ TT + T PT P+ Sbjct: 1564 PTTTPITTTTTVTPTPTPTGT---------QTPTTVLITTTTTMTPT-PT--------PT 1605 Query: 760 TTKPGTTT-IIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818 +TK T T I T ++A T G T P I + T+ T T+G+ P + Sbjct: 1606 STKSTTVTPITTTTTVTATPTPTGTQTPTMIP-ISTTTTVTPTPTPTTGSTGPPTHTSTA 1664 Query: 819 PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT 878 P + ++ P + T + + +S + PA+ T Sbjct: 1665 P----------IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE------MT 1708 Query: 879 GVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTL 938 T T +TS GGH+ S +T + GT T + + +A T S QTT Sbjct: 1709 STAPPSTPTAPTTTS----GGHTLSPPPSTTTSPPGT-PTRGTTTGSSSAPTPSTVQTTT 1763 Query: 939 TAAGGLTTPTITMQPVSQPT 958 T+A TPT T P+S P+ Sbjct: 1764 TSA---WTPTPT--PLSTPS 1778 Score = 100 bits (250), Expect = 1e-20 Identities = 118/470 (25%), Positives = 164/470 (34%), Gaps = 49/470 (10%) Query: 403 PATAATATSPTPNPVPSVPANPPKSP-------APAAAAPAVQPLTQVGITLLPQAAPAP 455 P T T+ TP P P+ P +P P Q T IT P P Sbjct: 1336 PTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1395 Query: 456 -----------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMR 504 P TTT V PT + PT T + VT TGT T Sbjct: 1396 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQAPT-- 1450 Query: 505 PASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSS 563 P + + VT T P G + T T + +P +G A T + P+ Sbjct: 1451 PTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTP 1510 Query: 564 APTVLSVPAGTTIVKTMAVTP-----GTTT-------LPATVKVASSPVMVSNPATRMLK 611 PT P T I T VTP GT T TV +P P T + Sbjct: 1511 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPIT 1570 Query: 612 TAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVP 671 T T + T T T +IT + T T + TTV +T T T+ +P Sbjct: 1571 TTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVT-PITTTTTVTATPTPTG 1629 Query: 672 GGSALISNLGKVMSVVQTKPVQTSAVTG---QASTGPVTQIIQTKGPLPAGTILKLVTSA 728 + + + +V T P T+ TG ST P+ ++ + P + T + + Sbjct: 1630 TQTPTMIPISTTTTVTPT-PTPTTGSTGPPTHTSTAPIAELTTSNPPPESST--PQTSRS 1686 Query: 729 DGKPTTIITTTQASGAGTKPTILGISSVSPST-TKPGTTTIIKTI--PMSAIITQAGATG 785 P T TT ++ P I S+ PST T P TT+ T+ P S + G Sbjct: 1687 TSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPT 1743 Query: 786 VTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVL 835 ++ G S T T + T+ P + P I G + VL Sbjct: 1744 RGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL 1793 Score = 95.5 bits (236), Expect = 5e-19 Identities = 128/512 (25%), Positives = 181/512 (35%), Gaps = 50/512 (9%) Query: 689 TKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP 748 T+P + T + T T P P T + T PT I TTT + P Sbjct: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTT-----PTPITTTTTVT-----P 1347 Query: 749 TILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMT--- 805 T + +P+TT TTT + P T G T++P I + T+ T T Sbjct: 1348 TPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTP-ITTTTTVTPTPTPTGTQ 1401 Query: 806 SGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAV 865 + T P T V T G Q T + T+ T G + TP ++ Sbjct: 1402 TPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTT----TVTPTPTPTGTQAPTPTAITTT 1457 Query: 866 KPAVTTLVVKGT-TGVTTLGTVTGTVSTSLAGAGGHS-TSASLATPITTLGTIATLSSQV 923 T GT T TT T T TV+ + G + T ++ T T T +Q Sbjct: 1458 STVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQT 1517 Query: 924 INPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILA 983 T IT + T G TPT T P+S T VT P+G + + + Sbjct: 1518 PTSTPITTTTTVTPTPTPTGTQTPTPT--PISTTTTVTPTPTPTGTQTP-----TTTPIT 1570 Query: 984 SPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQP 1043 + TT PT T T + + T T+ + P T T T TTT V P P Sbjct: 1571 TTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVT---ATPTP 1627 Query: 1044 TQVQFVCDRQEAAASLVTSTVGQQNGS------------VVRVCSNPPCETHETGTTNTA 1091 T Q + + VT T GS SNPP E+ T+ + Sbjct: 1628 TGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 1687 Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151 ++ + P E T +T TA ++ H + P Sbjct: 1688 SSPLTESTTLLSTLPPAIEMTSTAPPST-PTAPTTTSGGHTLSPPPSTTTSPPGTPTRGT 1746 Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183 TG+ A + S QT TSA + T T ++T Sbjct: 1747 TTGSSSAP--TPSTVQTTTTSAWTPTPTPLST 1776 Score = 92.4 bits (228), Expect = 4e-18 Identities = 136/551 (24%), Positives = 193/551 (35%), Gaps = 97/551 (17%) Query: 588 TLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQA 647 T P T+ ++ P T TS S T T PI T T TV Sbjct: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT---PITT-----TTTVTP-- 1347 Query: 648 QVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVT 707 T T T ++P + P + + P T T +T P+T Sbjct: 1348 ----------TPTPTGTQTPTTTP-----------ITTTTTVTPTPTPTGTQTPTTTPIT 1386 Query: 708 QIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTT 767 T P P T + TS TT +T T PT I++ + T P T Sbjct: 1387 -TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1445 Query: 768 IIKTIPMSAIITQAGATGVTSSPGIKSPITI-ITTKVMTSGTGAPAKIITAVPKIATGHG 826 P +AI T + T + G ++P T ITT + T P T P T Sbjct: 1446 TQAPTP-TAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAIT--- 1501 Query: 827 QQGVTQVVLKGAPGQPGTILRT-VPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGT 885 T + P GT T P+ VTP T + TT VT T Sbjct: 1502 ----TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPT 1557 Query: 886 VTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQ--VINPTAITVSAAQTTLTAAGG 943 TGT + + TPITT T+ + PT + ++ T Sbjct: 1558 PTGTQTPT-------------TTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604 Query: 944 LTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGD 1003 +T + T+ P++ T VT P+G + + +P+S + TT PT T T +G Sbjct: 1605 TSTKSTTVTPITTTTTVTATPTPTGTQTPTM--IPIS---TTTTVTPTPTPTTGSTG--- 1656 Query: 1004 VQPGTVT-------LVCSNPPCE------THETGTTNTATTTVVANLGGHPQPTQVQFVC 1050 P T T L SNPP E + T + T +TT+++ L P ++ Sbjct: 1657 --PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTL-----PPAIEMTS 1709 Query: 1051 DRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCE 1110 + + T+T G S PP T T T T T + S P Sbjct: 1710 TAPPSTPTAPTTTSGG------HTLSPPPSTTTSPPGTPTRGTTTGS------SSAPTPS 1757 Query: 1111 THETGTTNTAT 1121 T +T TT+ T Sbjct: 1758 TVQTTTTSAWT 1768 Score = 92.0 bits (227), Expect = 5e-18 Identities = 153/686 (22%), Positives = 230/686 (33%), Gaps = 94/686 (13%) Query: 900 HSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT------------- 946 H S+ T +TL T T++ PT T + TT T++ L+T Sbjct: 1153 HFNICSITTRPSTLTTFTTITLPT-TPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWIN 1211 Query: 947 ---PTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQG- 1002 P+ + T + AP +E + V D +S+ Q V++ + Sbjct: 1212 EDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNE 1271 Query: 1003 DVQPGTVTLV--CSNPP-----CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEA 1055 D +PG V + C N CE TT T TTT +P PT + Sbjct: 1272 DQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTE------NPTPTPITTTTTVTPT 1325 Query: 1056 AASLVT-STVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHET 1114 T ST + V P +T TT TT T+ T Sbjct: 1326 PTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1385 Query: 1115 GTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174 TT T T + G TP I+ T + +Q T T+ Sbjct: 1386 TTTTTVTPTPTPTGTQ------------TPTSTPITTTTTVTPTPTPTGTQTPT--TTPI 1431 Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234 +TT TV T P G ++P + S+ +P+ P Sbjct: 1432 TTTTTVTPTPTPT--------------GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPI 1477 Query: 1235 HAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPC 1294 +T T + G P + +TT TVT P+ T TQ ++ P Sbjct: 1478 TTTTTVTPTPTPTGTQTPTPTAI---------TTTTTVTPT-----PTPTGTQTPTSTPI 1523 Query: 1295 ETHETGT-------TNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEG 1347 T T T T T T + + V P +T TT TT T+ T P G Sbjct: 1524 TTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1583 Query: 1348 GQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTAL 1407 Q P T T T T S + P T++ T P++ P + T Sbjct: 1584 TQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTT 1643 Query: 1408 LAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNIT 1467 + P PT S P THT+T + ++++ PP +++ Q ++ + + T Sbjct: 1644 VTPTPTPTTGSTGP-------PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTT 1696 Query: 1468 SSSAITTTVSSTLTRAVTTVTQSTPVPGPSV--PPPEELQVSPGPRQQLPPRQLLQSAST 1525 S + + T T +T T T G PPP PG P R +S+ Sbjct: 1697 LLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG----TPTRGTTTGSSS 1752 Query: 1526 ALMGESAEVLSASQTPELPAAVDLSS 1551 A + + + S P + S Sbjct: 1753 APTPSTVQTTTTSAWTPTPTPLSTPS 1778 Score = 86.7 bits (213), Expect = 2e-16 Identities = 200/844 (23%), Positives = 281/844 (33%), Gaps = 155/844 (18%) Query: 717 PAGTILKL--VTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPM 774 P GT+ K + S +P+T+ T T T PT + + +TT P ++T++ T P Sbjct: 1146 PNGTVEKHFNICSITTRPSTLTTFTTI----TLPTTPTTFTTTTTTTTPTSSTVLSTTPK 1201 Query: 775 SAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKI---ITAVPKIATGHGQQGVT 831 + S G + GAP I P ++ Q V Sbjct: 1202 LCCLWSDWINEDHPSSGSDDG----DRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQ 1257 Query: 832 QV-------VLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGT---TGVT 881 V + K +PG ++ + +P T T +T Sbjct: 1258 LVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPIT 1317 Query: 882 TLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941 T TVT T + + ST ++ TPITT T+ PT T + QT T Sbjct: 1318 TTTTVTPTPTPT-------STQSTTPTPITTTTTVT--------PTP-TPTGTQTPTTTP 1361 Query: 942 GGLTTPTITMQPVSQPT-----QVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTI 996 T T T+ P PT T IT + V P + ++P T T T T Sbjct: 1362 ---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTP 1418 Query: 997 ADSG--QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQE 1054 +G P T T + P T T TA TT + + P PT Q Sbjct: 1419 TPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITT-TSTVTPTPTPTGTQTPTTTPI 1477 Query: 1055 AAASLVTST---VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCET 1111 + VT T G Q + + TT T T T G ++ P Sbjct: 1478 TTTTTVTPTPTPTGTQTPTPTAI------------TTTTTVTPTPTPTGTQTPTSTPIT- 1524 Query: 1112 HETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQT 1171 TT T T + G TP IS T + + QT T Sbjct: 1525 ----TTTTVTPTPTPTGTQ------------TPTPTPISTTTTVTPTP--TPTGTQTPTT 1566 Query: 1172 SATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAG 1231 + +TT TV T P G ++P V + ++ +P+ Sbjct: 1567 TPITTTTTVTPTPTP--------------TGTQTPTTVLITTTTTMTPTPTPTSTKSTTV 1612 Query: 1232 RHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSN 1291 +T T + G P M P+ STT TVT P+ T T + Sbjct: 1613 TPITTTTTVTATPTPTGTQTPTMIPI---------STTTTVT-------PTPTPTTGSTG 1656 Query: 1292 PPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHT-------ATTATSNGGTGQ 1344 PP TH TS A A+ SNPP E+ T+ + +TT S Sbjct: 1657 PP--TH---------TSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI 1705 Query: 1345 PEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAG 1404 PP+ T TTS G T+S + R +G A PS Sbjct: 1706 EMTSTAPPSTPTAPT--TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 1763 Query: 1405 TALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDS- 1463 T+ P PT + P TG ++V N A + T GD+ Sbjct: 1764 TSAWTPTPTP---LSTPSIIRTTGLRPYPSSVLICCVLND--TYYAPGEEVYNGTYGDTC 1818 Query: 1464 --VNITSSSAI-------TTTVSSTLTRAVTTVTQSTPVPGPSVP-----PPEELQVSPG 1509 VN + S + +T S T T + +T T S P PS P PPE P Sbjct: 1819 YFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDP- 1877 Query: 1510 PRQQ 1513 PRQ+ Sbjct: 1878 PRQE 1881 Score = 38.1 bits (87), Expect = 0.088 Identities = 37/144 (25%), Positives = 50/144 (34%), Gaps = 40/144 (27%) Query: 402 IPATAATATSPTPNPVP-----------------SVPANPPKSPAPAAAAPAVQPLTQVG 444 IP + T +PTP P + PP+S P + PLT+ Sbjct: 1636 IPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE-S 1694 Query: 445 ITLL-------------PQAAPAPPTTT----TIQVLPTVPGSSISVPTAARTQG----- 482 TLL P + P PTTT T+ P+ S PT T G Sbjct: 1695 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 1754 Query: 483 VPAVLKVTGPQATTGTPLVTMRPA 506 P+ ++ T A T TP P+ Sbjct: 1755 TPSTVQTTTTSAWTPTPTPLSTPS 1778 >gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens] Length = 1388 Score = 102 bits (254), Expect = 4e-21 Identities = 256/1144 (22%), Positives = 413/1144 (36%), Gaps = 158/1144 (13%) Query: 450 QAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQA 509 Q +P T L VP S P A+ + P + +G + PA + Sbjct: 64 QLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDS 123 Query: 510 GKAPVTVTSLPAGVR----MVVP---TQSAQGTVIGSSPQMSGMAALAAAAA-------A 555 G +++ GV M +P T SA V S ++S +A A ++ + Sbjct: 124 GTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMS 183 Query: 556 TQKIPPSSAPTVLSVPAGT-TIVKTMAVTPG---TTTLPATVKVASSPVMVSNPAT---- 607 T S P +L+ +G + + + PG T +PA A SP+ +++ T Sbjct: 184 TSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMS 243 Query: 608 RMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSP 667 ++L TA A S + T + I ++ S + Q +T G T L+ Sbjct: 244 KVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPT-PLMSDL 302 Query: 668 ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGP--------VTQIIQTKGPLPAG 719 S S L+S+ G S V + P+ + G+ ST P ++ + T LP+G Sbjct: 303 DSGIMSSLLMSSPG---SEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTA--LPSG 357 Query: 720 TILKLVTSADGKPTTIITTTQ---------------ASGAGTKPTILGISSVSPSTTKPG 764 + A G +TQ ASG + P + + S + ST G Sbjct: 358 VMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMG 417 Query: 765 T------TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818 +T+ KT+P S +T + T +S ++ ++VM++ AK A+ Sbjct: 418 APASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQL-TMAKTSGAM 476 Query: 819 PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT 878 P TG + Q A G+ T LR P G PVT +A + + + Sbjct: 477 P---TGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPAS 533 Query: 879 GVTTLGTVTGTVSTSLAG------AGGHS--------TSASLATPITTLGTIATLSSQVI 924 G ++ + VS +++ A G + TS +++TP+ T T + S+ ++ Sbjct: 534 GSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLM 593 Query: 925 NPTAITV-SAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILA 983 TA V S Q A+G L+ P +T P + T T + EA P ++L Sbjct: 594 RDTASGVMSCPQMRSLASGALSKPLMT--PKASGTMFTEKMTTTASEAMP------TLLM 645 Query: 984 SPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQP 1043 T + + D+ G + + S + T T + + + P Sbjct: 646 RDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRA---QDP 702 Query: 1044 TQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG-------TTNTATTATS 1096 + R + + +++ + Q+ + S P ++ G T++ +T T Sbjct: 703 GVMPASLMRAKVSGKMLSQPMSTQDPGGM---SMSPMKSMTAGGMQMNSPTSDVMSTPTV 759 Query: 1097 NMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGAL 1156 S P T + G + T SS G RA A+G A S A GA+ Sbjct: 760 RAWTSETMSTPLMRTSDPGERPSLLTRASSSG-EMSLPLMRAPASGEIATPLRSPAYGAM 818 Query: 1157 EAAQ----GSKSQCQTRQTSAT-STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211 A Q S Q A S M++ T + S G + + R P R + Q+ Sbjct: 819 SAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGG--MSMPLMRAPDSRVTSTSQM 876 Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271 P +S + P G S V A S P CE++ ST + Sbjct: 877 MPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPS---ACETV-----STELM 928 Query: 1272 VTALEALLCPSATVTQVC---SNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETG 1328 + + + T V S P +GT S S + S P ET +G Sbjct: 929 RASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEM--SMPLMETMASG 986 Query: 1329 TTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGT----TMSVSVGALLPDATSSH 1384 T T T+ +N R QTT T + T + A +TS Sbjct: 987 ATSTLQTSVANS--------------RSMSLSQTTYTVSGRMATAPIRASASGARSTSFM 1032 Query: 1385 RTVESGLEVAAAPSVTPQA-GTALLAPFPT---QRVCSNPPCETHETGTTHTATTVTSNM 1440 R SG P T G + P T R S P GT T T M Sbjct: 1033 RASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVM 1092 Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500 S+ P A+D GE ++ +NIT+S + T+ + T P + PP Sbjct: 1093 ST---PEIKATDSGEASTSH---INITASGSKPTSHMTATT------------PETAKPP 1134 Query: 1501 PEEL 1504 P+E+ Sbjct: 1135 PKEV 1138 Score = 84.0 bits (206), Expect = 1e-15 Identities = 198/907 (21%), Positives = 348/907 (38%), Gaps = 128/907 (14%) Query: 416 PVPSVPANPPKS--PAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSIS 473 P+ SVP S P PA A A+ P +T LP PT Q +P PGS Sbjct: 323 PLLSVPDAGEMSTLPKPAPDAEAMSPAL---MTALPSGVM--PT----QTMPA-PGSGAM 372 Query: 474 VPTAARTQGVPAVLKVTGPQATTGTPLVTMRP--ASQAGKAPVTVTSLPAGVRMVVPTQS 531 P + TQ V + + P T + +++ P A +G + PA M + Sbjct: 373 SPWS--TQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM----ST 426 Query: 532 AQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPA 591 Q TV S + + + ++ + + ++A V+S A T+ KT P T ++ A Sbjct: 427 LQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMS--AQLTMAKTSGAMP-TGSMKA 483 Query: 592 TVKV---ASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648 K A++ +S P R + A ++A+ T + P +TV SG++++ Q Sbjct: 484 VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRA 543 Query: 649 VVT---------TVVGGVTKTI---TLVKSPISVP------GGSALISNLGKVMSVVQTK 690 V+ T+ G+T + +S P GS + S V + Sbjct: 544 PVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSC 603 Query: 691 PVQTSAVTGQASTGPVTQIIQTKGPLPAGTIL--KLVTSADGKPTTIITTTQASGAGTKP 748 P S +G S +T P +GT+ K+ T+A T++ SGA + P Sbjct: 604 PQMRSLASGALSKPLMT-------PKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMP 656 Query: 749 TILGISS--VSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTS 806 + +S +S S + + + T M+A T S G+ P+ + Sbjct: 657 QMTDTASGGLSASLMRDTASGAMSTSQMTA----------TVSGGMSMPL----MRAQDP 702 Query: 807 GTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVK 866 G PA ++ A K++ G+ + + G + ++++ GG+++ +P + Sbjct: 703 GV-MPASLMRA--KVS---GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMST 756 Query: 867 PAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINP 926 P V + + + G + L A S+S ++ P+ +++ + +P Sbjct: 757 PTVRAWTSETMSTPLMRTSDPGERPSLLTRA---SSSGEMSLPLMRAPASGEIATPLRSP 813 Query: 927 TAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLI-TAPSGVEAQPVHDLPVSILASP 985 +SA Q T TA+G +++ P+S + L + SG + P+ P S + S Sbjct: 814 AYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST 873 Query: 986 TTEQPTA-----TVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGH 1040 + PTA T+ + G V S+P +GT +T Sbjct: 874 SQMMPTASGDMCTLPVRAPASGGV---------SSPLVRAPASGTMSTPLR--------- 915 Query: 1041 PQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAG 1100 +P+ + V A++ + Q V S P +GT S MA Sbjct: 916 -RPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGT--MPMPLMSAMAS 972 Query: 1101 QHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEA-A 1159 S P ET +G T+T T+++ ++R + T + +AT + A A Sbjct: 973 GE-MSMPLMETMASGATSTLQTSVA--------NSRSMSLSQTTYTVSGRMATAPIRASA 1023 Query: 1160 QGSKSQCQTRQTSATSTTMTV-MATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKV 1218 G++S R + + S M + AT + C G + A + G S PL + Sbjct: 1024 SGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMS------TPL---M 1074 Query: 1219 RLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL 1278 R S P P +ST + + +GE + + + G P++ +T T E Sbjct: 1075 RASGPGTMSTPQTAFG-VMSTPEI--KATDSGEASTSHINITASGSKPTSHMTATTPETA 1131 Query: 1279 LCPSATV 1285 P V Sbjct: 1132 KPPPKEV 1138 Score = 60.8 bits (146), Expect = 1e-08 Identities = 252/1255 (20%), Positives = 427/1255 (34%), Gaps = 282/1255 (22%) Query: 441 TQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP---AVLKVTGPQATTG 497 + V + ++ +A P T+T Q++ + ++S P GVP A+ P + +G Sbjct: 44 SHVQLPIVSTSASDPGGTST-QLMTSPVFDTMSAPL----MGVPNSGALSPPLMPASDSG 98 Query: 498 TPLVTMRPASQAGK-APVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAAT 556 + PAS +G +P+ + +L +G + + S G + Sbjct: 99 ALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVM-------------------- 138 Query: 557 QKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQ 616 +P ++++P T+ T+ V P + + A S +V P Sbjct: 139 -------SPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPI---------- 181 Query: 617 VGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSAL 676 + TS S A +T P++ SG ++ ++ + GV T P+ P A Sbjct: 182 MSTSSSEAMST---PLMLAPDSGELSPI----LMQDMNPGVMST-----QPVPAPSSEA- 228 Query: 677 ISNLGKVMSVVQTKPVQTSAVTGQAST----GPVTQIIQTKGPLPAGTILKLVTSADGKP 732 MS +Q T A++ T G ++ ++ + A + L + A G Sbjct: 229 -------MSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGT 281 Query: 733 TTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792 + T+TQ SG P + + S I+ ++ MS+ ++ +T + S P Sbjct: 282 SPQPTSTQNSGGIPTPLMSDLDS-----------GIMSSLLMSSPGSEVMSTPLLSVPDA 330 Query: 793 KSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMG 852 T+ K ++TA+P GV APG + Sbjct: 331 GEMSTL--PKPAPDAEAMSPALMTALPS--------GVMPTQTMPAPGSGA-----MSPW 375 Query: 853 GVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGA---GGHST------- 902 + V +S T V V L + G +ST L GA G ST Sbjct: 376 STQNVDSEMMSNPPVRATASGVMSAPPVRALDS--GAMSTPLMGAPASGNMSTLQKTVPA 433 Query: 903 SASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTL 962 S ++ T + T+ + +S++ ++ TA V +AQ T+ G PT +M+ V++ Q Sbjct: 434 SGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSG-AMPTGSMKAVAK--QYKR 490 Query: 963 ITAPSGVEAQPVHDLP---------VSILASPTTEQPTATVTIADSGQGDVQPGTVTLVC 1013 TA SG + P+ P V+ AS T P TV + S V+ Sbjct: 491 ATA-SGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAM 549 Query: 1014 SNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVR 1073 S P T +G T+ A + +A S ST Sbjct: 550 SMPQMRTMASGLTSAA----------------------QMKAMTSGAMST---------- 577 Query: 1074 VCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQR 1133 P T +T + + +G C P + +G + + G Sbjct: 578 -----PLMTAQTSGSTSTLLMRDTASGVMSC--PQMRSLASGALSKPLMTPKASGTMFTE 630 Query: 1134 DARRACAAGTPAVIRISVATGAL------EAAQGSKSQCQTRQTSATSTTMTVMATGAPC 1187 + P ++ +GAL + A G S R T++ + + + M Sbjct: 631 KMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATV-- 688 Query: 1188 SAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSV 1247 +G + P M + G PA + A +S K+ LS P P G +S + M + Sbjct: 689 -SGGMSMPLMRAQDPGVMPASLMRAKVSGKM-LSQPMSTQDPGG-----MSMSPMKSMTA 741 Query: 1248 GAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATT 1307 G +Q SP++ V T A ++ S P T + G + T Sbjct: 742 GG-----------MQMNSPTSDVMSTPTVR-----AWTSETMSTPLMRTSDPGERPSLLT 785 Query: 1308 SNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGT 1367 + S + S P +G T + + G P Q T+T + Sbjct: 786 RASSSGEM--SLPLMRAPASGEIATPLRSPAYGAMSAP---------------QMTATAS 828 Query: 1368 TMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHET 1427 M S +P + + + + S + L P RV S Sbjct: 829 GMMSS----MPQVKAP---ISGAMSMPLTRSTASGGMSMPLMRAPDSRVTS--------- 872 Query: 1428 GTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTV 1487 TS M P AS GD + + + VSS L RA + Sbjct: 873 ---------TSQMM------PTAS---------GDMCTLPVRAPASGGVSSPLVRAPASG 908 Query: 1488 TQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAE-VLSASQTPELPAA 1546 T STP+ PS ++ ST LM SA +S +QT Sbjct: 909 TMSTPLRRPSA---------------------CETVSTELMRASASGHMSTAQT------ 941 Query: 1547 VDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTG 1606 T S G A+ + P + ++S+P + A T+TL + Sbjct: 942 -----TAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL-METMASGATSTLQTSV 995 Query: 1607 LTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661 ++++ + AT +A A A + +A + PM A A+ Sbjct: 996 ANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATAS 1050 Score = 52.0 bits (123), Expect = 6e-06 Identities = 74/361 (20%), Positives = 134/361 (37%), Gaps = 53/361 (14%) Query: 403 PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQV----GITLLPQAAPAPPTT 458 PA A + + ++ P+ AP + A ++ PLT+ G+++ AP T Sbjct: 813 PAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSM-PLTRSTASGGMSMPLMRAPDSRVT 871 Query: 459 TTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP-QATTGTPL----------VTMRPAS 507 +T Q++PT G ++P A G + V P T TPL + AS Sbjct: 872 STSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRAS 931 Query: 508 QAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTV 567 +G T+ M P A + P MS MA+ + + + + T+ Sbjct: 932 ASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTL 991 Query: 568 LSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT 627 T++ + +++ TT + ++A++P+ S R A V S+ Sbjct: 992 -----QTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSM------ 1040 Query: 628 STRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVV 687 P+ SG Q+ T G++ +P+ G +S V+ Sbjct: 1041 -PMPLPRATASGCGMGMSMPQMTATDSRGMS-------TPLMRASGPGTMSTPQTAFGVM 1092 Query: 688 QTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTK 747 T ++ + +G+AST + +T++ KPT+ +T T A Sbjct: 1093 STPEIKATD-SGEASTSHIN-----------------ITASGSKPTSHMTATTPETAKPP 1134 Query: 748 P 748 P Sbjct: 1135 P 1135 >gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens] Length = 372 Score = 95.9 bits (237), Expect = 4e-19 Identities = 77/265 (29%), Positives = 118/265 (44%), Gaps = 31/265 (11%) Query: 45 IVVFGGGNEG-IVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCDGTRLLVFGGMVE 102 + + GG N ++H + +QW + +G +P A++ C R+ VFGG + Sbjct: 50 VFIVGGANPNRSFSDVHTMDLGKHQWDLDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQ 109 Query: 103 YGKYSNDLYELQASRWEWKRLKAKTPK-NGPPPCPRLGHSFSL-VGNKCYLFGGLANDSE 160 G N L L W TP+ PPP PR H+ S +GN+ Y+FGG ++ Sbjct: 110 SGN-RNCLQVLNPETRTWT-----TPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQ 163 Query: 161 DPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVI 220 ++ L++ + + + W P T G P PR H V +KL I Sbjct: 164 PVQDT------KLHVFD----ANTLTWSQPETLGNPPSPRHGHVMVA------AGTKLFI 207 Query: 221 YGGMSGCRL-GDLWTLDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMD 279 +GG++G R DL +DI + W K + +G AP + HSA +G +Y+FGG P Sbjct: 208 HGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGAL 267 Query: 280 DVKVATHEKEWKCTNTLACLNLDTM 304 D H +E T L DT+ Sbjct: 268 DTMYQYHTEEQHWT----LLKFDTL 288 Score = 73.2 bits (178), Expect = 2e-12 Identities = 74/246 (30%), Positives = 114/246 (46%), Gaps = 45/246 (18%) Query: 131 GPPPCPRLGHSFSL---VGN----KCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSG 183 G PC R+GHS S VGN K ++ GG N R +D++ ++L G Sbjct: 25 GDSPCARVGHSCSYLPPVGNAKRGKVFIVGGA---------NPNRSFSDVHTMDL----G 71 Query: 184 VVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGG--MSGCRLGDLWTLDIDTLT 241 WD+ G+LP R H + + ++ ++GG SG R L L+ +T T Sbjct: 72 KHQWDLDTCKGLLP--RYEHASFI---PSCTPDRIWVFGGANQSGNR-NCLQVLNPETRT 125 Query: 242 WNKPSLSGVAPLPRSLH-SATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLN 300 W P ++ P PR+ H S+ IGN++YVFGG + A ++ K L + Sbjct: 126 WTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGG-------GERGAQPVQDTK----LHVFD 174 Query: 301 LDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLE 360 +T+ W +TL N P R GH VA T+L+I G G R + + + C D+ ++ Sbjct: 175 ANTLTWSQ--PETL-GNPPSPRHGHVMVAAGTKLFIHGGLAGDR--FYDDLHCIDISDMK 229 Query: 361 TEKPPP 366 +K P Sbjct: 230 WQKLNP 235 Score = 59.3 bits (142), Expect = 4e-08 Identities = 38/120 (31%), Positives = 53/120 (44%), Gaps = 6/120 (5%) Query: 27 GPVPRPRHGHRAVAIKELIVVFGG-GNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAY 85 G P PRHGH VA + + GG + D+LH + + +W G P GCAA+ Sbjct: 187 GNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAH 246 Query: 86 GFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLV 145 V G + +FGGM G + +Y+ W LK T P RL HS ++ Sbjct: 247 SAVAMGKHVYIFGGMTPAGAL-DTMYQYHTEEQHWTLLKFDTLL----PPGRLDHSMCII 301 Score = 32.7 bits (73), Expect = 3.7 Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 2/65 (3%) Query: 18 RWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGN-EGIVDELHVYNTATNQWFIPAVRG 76 +W+++ +G P H AVA+ + + +FGG G +D ++ Y+T W + Sbjct: 229 KWQKL-NPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLLKFDT 287 Query: 77 DIPPG 81 +PPG Sbjct: 288 LLPPG 292 >gi|7657301 kelch domain containing 2 [Homo sapiens] Length = 406 Score = 88.6 bits (218), Expect = 6e-17 Identities = 77/273 (28%), Positives = 113/273 (41%), Gaps = 43/273 (15%) Query: 30 PRPRHGHRAVAIKELIVVFGGGNEGIV----------DELHVYNTATNQWFIPAVRGDIP 79 P R GH AV+ + V+GG V +EL +YN T +W GD+P Sbjct: 29 PAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVP 88 Query: 80 PGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWE----WKRLKAKTPKNGPPPC 135 P + VC L +FGG G +N Y L + + W+R+ + G PP Sbjct: 89 PSMSGSCAVCVDRVLYLFGGHHSRGN-TNKFYMLDSRSTDRVLQWERIDCQ----GIPPS 143 Query: 136 PRLGHSFSLVGNKCYLFGGLANDSEDP-------------KNNIPRYLND-LYILELRPG 181 + + NK FGG ED ++ PR ND ++IL+ Sbjct: 144 SKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTE-- 201 Query: 182 SGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTLT 241 W PIT G P PR +H + V G R+ DL L++DT Sbjct: 202 --TFTWSQPITTGKAPSPRAAHACATVGNRG-----FVFGGRYRDARMNDLHYLNLDTWE 254 Query: 242 WNKPSLSGVAPLPRSLHSATTI-GNKMYVFGGW 273 WN+ G+ P+ RS HS T + + +++FGG+ Sbjct: 255 WNELIPQGICPVGRSWHSLTPVSSDHLFLFGGF 287 Score = 68.9 bits (167), Expect = 5e-11 Identities = 74/287 (25%), Positives = 111/287 (38%), Gaps = 73/287 (25%) Query: 88 VCDGTRLLVFGGMVEY---GKYSNDL-------YELQASRWEWKRLKAKTPKNGPPPCPR 137 V DG + V+GG G Y L Y ++ RW+ K G P Sbjct: 38 VSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWK------KINTEGDVPPSM 91 Query: 138 LGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLP 197 G V YLFGG + N N Y+L+ R V+ W+ G+ P Sbjct: 92 SGSCAVCVDRVLYLFGG-----HHSRGNT----NKFYMLDSRSTDRVLQWERIDCQGIPP 142 Query: 198 PPRESHTAVVYTEKDNKKSKLVIYGGMSGCR----LG-------DLWT------------ 234 ++ VY K+KL+ +GG LG W Sbjct: 143 SSKDKLGVWVY------KNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVH 196 Query: 235 -LDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCT 293 LD +T TW++P +G AP PR+ H+ T+GN+ +VFGG D ++ Sbjct: 197 ILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGG----RYRDARM---------- 242 Query: 294 NTLACLNLDTMAWETILMDTLEDNIPRARAGHCAVAINT-RLYIWSG 339 N L LNLDT W ++ + P R+ H +++ L+++ G Sbjct: 243 NDLHYLNLDTWEWNELIPQGI---CPVGRSWHSLTPVSSDHLFLFGG 286 Score = 41.6 bits (96), Expect = 0.008 Identities = 55/245 (22%), Positives = 86/245 (35%), Gaps = 38/245 (15%) Query: 134 PCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITY 193 P R GH G +++GG ++ + +L+I + G W T Sbjct: 29 PAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGR----WKKINTE 84 Query: 194 GVLPPPRESHTAVVYTEKDNKKSKLVIYGGM-SGCRLGDLWTLDIDT----LTWNKPSLS 248 G +PP AV L ++GG S + LD + L W + Sbjct: 85 GDVPPSMSGSCAVCVDRV------LYLFGGHHSRGNTNKFYMLDSRSTDRVLQWERIDCQ 138 Query: 249 GVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVK-----------VATHEKEWKCTNTLA 297 G+ P + NK+ FGG+ L D V ++H + W + + Sbjct: 139 GIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGW--NDHVH 196 Query: 298 CLNLDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLW 357 L+ +T W P RA H + R +++ GR YR A N DL Sbjct: 197 ILDTETFTWS---QPITTGKAPSPRAAHACATVGNRGFVFGGR--YRDARMN-----DLH 246 Query: 358 YLETE 362 YL + Sbjct: 247 YLNLD 251 Score = 39.3 bits (90), Expect = 0.040 Identities = 40/166 (24%), Positives = 68/166 (40%), Gaps = 15/166 (9%) Query: 25 WSGPV-----PRPRHGHRAVAIKELIVVFGGG-NEGIVDELHVYNTATNQWFIPAVRGDI 78 WS P+ P PR H + VFGG + +++LH N T +W +G Sbjct: 205 WSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDARMNDLHYLNLDTWEWNELIPQGIC 264 Query: 79 PPGCAAYGFV-CDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPR 137 P G + + L +FGG + +D + S+ EW + + PR Sbjct: 265 PVGRSWHSLTPVSSDHLFLFGGFTTDKQPLSDAWTYCISKNEWIQFNHPYTEK-----PR 319 Query: 138 LGHSFSLVG-NKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGS 182 L H+ + +FGG AN+ ++ + N++ I ++P S Sbjct: 320 LWHTACASDEGEVIVFGGCANNL--LVHHRAAHSNEILIFSVQPKS 363 Score = 37.7 bits (86), Expect = 0.12 Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 8/94 (8%) Query: 246 SLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMA 305 S+ P RS H A + G M+V+GG+ + + +E L N++T Sbjct: 23 SMELACPAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPRE-----ELWIYNMETGR 77 Query: 306 WETILMDTLEDNIPRARAGHCAVAINTRLYIWSG 339 W+ I E ++P + +G CAV ++ LY++ G Sbjct: 78 WKKI---NTEGDVPPSMSGSCAVCVDRVLYLFGG 108 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.125 0.361 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 87,798,836 Number of Sequences: 37866 Number of extensions: 4689255 Number of successful extensions: 42698 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 209 Number of HSP's successfully gapped in prelim test: 1118 Number of HSP's that attempted gapping in prelim test: 21071 Number of HSP's gapped (non-prelim): 10440 length of query: 2035 length of database: 18,247,518 effective HSP length: 118 effective length of query: 1917 effective length of database: 13,779,330 effective search space: 26414975610 effective search space used: 26414975610 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.