Guide to the Human Genome
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Search of human proteins with 98986457

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|98986457 host cell factor 1 [Homo sapiens]
         (2035 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|98986457 host cell factor 1 [Homo sapiens]                        4024   0.0  
gi|7019405 host cell factor C2 [Homo sapiens]                         594   e-169
gi|116284392 mucin 2 precursor [Homo sapiens]                         217   8e-56
gi|91982772 mucin 17 [Homo sapiens]                                   189   2e-47
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]      164   6e-40
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]           161   5e-39
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]           161   5e-39
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]           161   5e-39
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]           161   7e-39
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]           161   7e-39
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...   161   7e-39
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]           161   7e-39
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]           160   2e-38
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]           160   2e-38
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]           160   2e-38
gi|161019170 mucin 5AC [Homo sapiens]                                 149   3e-35
gi|167736355 mucin 4 isoform a [Homo sapiens]                         140   1e-32
gi|83367077 mucin 16 [Homo sapiens]                                   138   6e-32
gi|151301154 mucin 6, gastric [Homo sapiens]                          132   4e-30
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                       129   4e-29
gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sap...   126   2e-28
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...   119   4e-26
gi|163965366 nascent polypeptide-associated complex alpha subuni...   118   5e-26
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]           118   7e-26
gi|16945972 kelch domain containing 3 [Homo sapiens]                  114   1e-24
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                       112   4e-24
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]             106   3e-22
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]    102   4e-21
gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens]     96   4e-19
gi|7657301 kelch domain containing 2 [Homo sapiens]                    89   6e-17

>gi|98986457 host cell factor 1 [Homo sapiens]
          Length = 2035

 Score = 4024 bits (10437), Expect = 0.0
 Identities = 2035/2035 (100%), Positives = 2035/2035 (100%)

Query: 1    MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELH 60
            MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELH
Sbjct: 1    MASAVSPANLPAVLLQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELH 60

Query: 61   VYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEW 120
            VYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEW
Sbjct: 61   VYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEW 120

Query: 121  KRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRP 180
            KRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRP
Sbjct: 121  KRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRP 180

Query: 181  GSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTL 240
            GSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTL
Sbjct: 181  GSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTL 240

Query: 241  TWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLN 300
            TWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLN
Sbjct: 241  TWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLN 300

Query: 301  LDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLE 360
            LDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLE
Sbjct: 301  LDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLE 360

Query: 361  TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV 420
            TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV
Sbjct: 361  TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV 420

Query: 421  PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAART 480
            PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAART
Sbjct: 421  PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAART 480

Query: 481  QGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS 540
            QGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS
Sbjct: 481  QGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS 540

Query: 541  PQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPV 600
            PQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPV
Sbjct: 541  PQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPV 600

Query: 601  MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT 660
            MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT
Sbjct: 601  MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT 660

Query: 661  ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720
            ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT
Sbjct: 661  ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720

Query: 721  ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780
            ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ
Sbjct: 721  ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780

Query: 781  AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG 840
            AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG
Sbjct: 781  AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG 840

Query: 841  QPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH 900
            QPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH
Sbjct: 841  QPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH 900

Query: 901  STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960
            STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV
Sbjct: 901  STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960

Query: 961  TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET 1020
            TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET
Sbjct: 961  TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET 1020

Query: 1021 HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC 1080
            HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC
Sbjct: 1021 HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC 1080

Query: 1081 ETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACA 1140
            ETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACA
Sbjct: 1081 ETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACA 1140

Query: 1141 AGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE 1200
            AGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE
Sbjct: 1141 AGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE 1200

Query: 1201 PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCES 1260
            PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCES
Sbjct: 1201 PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCES 1260

Query: 1261 LQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNP 1320
            LQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNP
Sbjct: 1261 LQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNP 1320

Query: 1321 PCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDA 1380
            PCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDA
Sbjct: 1321 PCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDA 1380

Query: 1381 TSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNM 1440
            TSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNM
Sbjct: 1381 TSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNM 1440

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP
Sbjct: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQE 1560
            PEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQE
Sbjct: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQE 1560

Query: 1561 SAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA 1620
            SAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA
Sbjct: 1561 SAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA 1620

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
            AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT
Sbjct: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680

Query: 1681 TIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTV 1740
            TIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTV
Sbjct: 1681 TIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTV 1740

Query: 1741 PSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPP 1800
            PSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPP
Sbjct: 1741 PSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPP 1800

Query: 1801 PSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGT 1860
            PSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGT
Sbjct: 1801 PSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGT 1860

Query: 1861 AYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKI 1920
            AYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKI
Sbjct: 1861 AYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKI 1920

Query: 1921 IEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII 1980
            IEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII
Sbjct: 1921 IEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAII 1980

Query: 1981 FRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSAPKKSKADGQ 2035
            FRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSAPKKSKADGQ
Sbjct: 1981 FRIAARNEKGYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSAPKKSKADGQ 2035


>gi|7019405 host cell factor C2 [Homo sapiens]
          Length = 792

 Score =  594 bits (1531), Expect = e-169
 Identities = 301/581 (51%), Positives = 382/581 (65%), Gaps = 31/581 (5%)

Query: 19  WKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDI 78
           W+RV  ++GPVPR RHGHRAVAI+EL+++FGGGNEGI DELHVYNTATNQWF+PAVRGDI
Sbjct: 9   WRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWFLPAVRGDI 68

Query: 79  PPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRL 138
           PPGCAA+GFVCDGTR+LVFGGMVEYG+YSN+LYELQASRW WK++K   P +G PPCPRL
Sbjct: 69  PPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPCPRL 128

Query: 139 GHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPP 198
           GHSFSL GNKCYLFGGLAN+SED  NN+PRYLND Y LEL+ GSGVV W IP+T GV+P 
Sbjct: 129 GHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPS 188

Query: 199 PRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTLTWNKPSLSGVAPLPRSLH 258
           PRESHTAV+Y +KD+   K+ ++GGM G RL DLW LD++T++W+KP   G  PLPRSLH
Sbjct: 189 PRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLH 248

Query: 259 SATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLED-- 316
           +A+ IGNKMY+FGGWVP   ++ + + H+ EW+CT++ + LNLDT  W T++ D+ ED  
Sbjct: 249 TASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLVSDSQEDKK 308

Query: 317 -NIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRA 375
            + PR RAGHCAVAI TRLY WSGRDGY+KA N+QVCCKDLWYL+TEKPP P++VQL++A
Sbjct: 309 NSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKA 368

Query: 376 NTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAP 435
            TNS  V W  V+T + YLLQL   D+P  AA++ S               S AP     
Sbjct: 369 TTNSFHVKWDEVSTVEGYLLQLST-DLPYQAASSDS---------------SAAPNMQGV 412

Query: 436 AVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVL--KVTGPQ 493
            + P  Q    ++P +      +T  +   T   S  + P         A+L   +    
Sbjct: 413 RMDPHRQGSNNIVPNSINDTINSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNA 472

Query: 494 ATTGTPLVTMRPASQA--GKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAA 551
           +   + +V M   ++     A V V S    VR V+P  S   TV  S+  M     +  
Sbjct: 473 SNHNSHVVDMLRKNEGPHTSANVGVLSSCLDVRTVIPETSVSSTV-SSTQTMVTQQTIKT 531

Query: 552 AAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPAT 592
            +++T          V+      T   T +    T  LPAT
Sbjct: 532 ESSSTN-------GAVVKDETSLTTFSTKSEVDETYALPAT 565



 Score =  244 bits (624), Expect = 5e-64
 Identities = 128/281 (45%), Positives = 173/281 (61%), Gaps = 17/281 (6%)

Query: 1736 LAGTVPSTVALLPSTA--TESLAPSNTFVAPQPVVVASPAKLQA-------AATLTEVAN 1786
            ++ TV ST  ++      TES + +   V  +  +     K +        A  ++ V  
Sbjct: 513  VSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVET 572

Query: 1787 GIESLGVKPDLPPPPSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGT-- 1844
               +     + P  P       E QW DVG+ K    +V+ ++L P     S   +G   
Sbjct: 573  HATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGK-QSISKVGNAD 631

Query: 1845 VPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPD 1904
            VPDY+ LKKQ+L PGT Y+FRVA IN CG GPFS+IS FKTC+PGFPGAP A++ISK+ +
Sbjct: 632  VPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVE 691

Query: 1905 GAHLTWEPPSVTSGKIIEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSS 1964
            G HL+WEPP+  SG I+EYS YLAI+++Q         P+QL FMR+YCG   SC+V + 
Sbjct: 692  GIHLSWEPPTSPSGNILEYSAYLAIRTAQI-----QDNPSQLVFMRIYCGLKTSCIVTAG 746

Query: 1965 SLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSK 2005
             L+NAHIDYT++PAI+FRI+A+NEKGYGPATQVRWLQ  +K
Sbjct: 747  QLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNK 787


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score =  217 bits (553), Expect = 8e-56
 Identities = 307/1287 (23%), Positives = 418/1287 (32%), Gaps = 165/1287 (12%)

Query: 403  PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455
            P T  T  +PTP P       + P     +  P       Q  T   IT      P P  
Sbjct: 2751 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2810

Query: 456  ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
                     P TTT  V PT   +    PT   T  +     VT     TGT   T  P 
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 2867

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565
            +      VT T  P G +    T     T +  +P  +G           T  + P+  P
Sbjct: 2868 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2925

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T    P  T I  T  VTP T T   T    ++P+  +   T        Q  T+    T
Sbjct: 2926 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
             T+  P  T   + T T      + TT     T T T  ++P + P           + +
Sbjct: 2985 TTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3030

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAG 745
                 P  T   T   +T P+T    T  P P  T  +  T+     TT +T T      
Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3089

Query: 746  TKPT---ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801
              PT   I   ++V+P+ T  GT T   T I  +  +T       T +P   +PIT  TT
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3148

Query: 802  KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGT-ILR 847
               T       + T  P    T V    T  G Q        T   +   P   GT    
Sbjct: 3149 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3208

Query: 848  TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907
            T P+     VTP          TT  +  TT VT   T TGT +          T+  + 
Sbjct: 3209 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPIT 3259

Query: 908  TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967
            T  T   T     +Q    T IT +   T      G  TPT T  P++  T VT    P+
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3317

Query: 968  GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027
            G +         + + + TT  PT T T   +        T T+  +  P  T    TT 
Sbjct: 3318 GTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372

Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSN------- 1077
              TTT V      P PT  Q          + VT T    G Q  +   + +        
Sbjct: 3373 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3429

Query: 1078 PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137
             P  T    TT   TT T         +  P  T  T TT T T   +  G         
Sbjct: 3430 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3481

Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197
                 TP    I+  T        + +  QT  T+  +TT TV  T  P           
Sbjct: 3482 -----TPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP----------- 3523

Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257
                G ++P    +   ++     +P+    P        +T   T +  G   P   P+
Sbjct: 3524 ---TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310
                     +TT TVT       P+ T TQ  +  P  T  T T       T T TT+  
Sbjct: 3581 ---------TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626

Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370
             +   V   P     +T TT   TT T+   T  P G Q P       T   T T T   
Sbjct: 3627 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3686

Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430
                   P  T++  T          P+ TP   T  + P PT      P      T TT
Sbjct: 3687 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3746

Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------L 1480
             T T T T   +    P    +      +  G     T+    TTTV+ T          
Sbjct: 3747 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3806

Query: 1481 TRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGE 1530
            T  +TT T  TP P P       + P      V+P P     Q P    + + +T     
Sbjct: 3807 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3866

Query: 1531 SAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVD 1583
            +        T  +     ++ T  P+  Q    + +  T  V P P       PT + + 
Sbjct: 3867 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3926

Query: 1584 QLS--LPQELMAEAQAGTTTLMVTGLT 1608
              +   P       Q  TTT + T  T
Sbjct: 3927 TTTTVTPTPTPTGTQTPTTTPITTTTT 3953



 Score =  217 bits (553), Expect = 8e-56
 Identities = 308/1287 (23%), Positives = 418/1287 (32%), Gaps = 165/1287 (12%)

Query: 403  PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455
            P T  T  +PTP P       + P     +  P       Q  T   IT      P P  
Sbjct: 2912 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2971

Query: 456  ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
                     P TTT  V PT   +    PT   T  +     VT     TGT   T  P 
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3028

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565
            +      VT T  P G +    T     T +  +P  +G           T  + P+  P
Sbjct: 3029 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3086

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T    P  T I  T  VTP T T   T    ++P+  +   T        Q  T+    T
Sbjct: 3087 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
             T+  P  T   + T T      + TT     T T T  ++P + P           + +
Sbjct: 3146 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3191

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744
                 P  T   T   +T P+T     T  P P GT     T      TT+  T   +G 
Sbjct: 3192 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 3250

Query: 745  GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801
             T  T  I   ++V+P+ T  GT T   T I  +  +T       T +P   +PIT  TT
Sbjct: 3251 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3309

Query: 802  KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGTIL-R 847
               T       + T  P    T V    T  G Q        T   +   P   GT    
Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369

Query: 848  TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907
            T P+     VTP          TT  +  TT VT   T TGT +          T+  + 
Sbjct: 3370 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------TTTPIT 3420

Query: 908  TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967
            T  T   T     +Q    T IT +   T      G  TPT T  P++  T VT    P+
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3478

Query: 968  GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027
            G +         + + + TT  PT T T   +        T T+  +  P  T    TT 
Sbjct: 3479 GTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533

Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSNP------ 1078
              TTT V      P PT  Q          + VT T    G Q  +   + +        
Sbjct: 3534 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590

Query: 1079 -PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137
             P  T    TT   TT T         +  P  T  T TT T T   +  G         
Sbjct: 3591 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3642

Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197
                 TP    I+  T        + +Q  T  T+  +TT TV  T  P           
Sbjct: 3643 -----TPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT---------- 3685

Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257
                G ++P    +   ++     +P+    P        +T   T +  G   P   P+
Sbjct: 3686 ----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310
                     +TT TVT       P+ T TQ  +  P  T  T T       T T TT+  
Sbjct: 3742 ---------TTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787

Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370
             +   V   P     +T TT   TT T+   T  P G Q P       T   T T T   
Sbjct: 3788 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3847

Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430
                   P  T++  T          P+ TP   T  + P PT      P      T TT
Sbjct: 3848 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3907

Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------L 1480
             T T T T   +    P    +      +  G     T+    TTTV+ T          
Sbjct: 3908 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3967

Query: 1481 TRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGE 1530
            T  +TT T  TP P P       + P      V+P P     Q P    + + +T     
Sbjct: 3968 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4027

Query: 1531 SAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVD 1583
            +        T  +     ++ T  P+  Q    + +  T  V P P       PT + + 
Sbjct: 4028 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4087

Query: 1584 QLS--LPQELMAEAQAGTTTLMVTGLT 1608
              +   P       Q  TTT + T  T
Sbjct: 4088 TTTTVTPTPTPTGTQTPTTTPITTTTT 4114



 Score =  217 bits (552), Expect = 1e-55
 Identities = 304/1283 (23%), Positives = 421/1283 (32%), Gaps = 153/1283 (11%)

Query: 403  PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455
            P T  T  +PTP P       + P     +  P       Q  T   IT      P P  
Sbjct: 3073 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3132

Query: 456  ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
                     P TTT  V PT   +    PT   T  +     VT     TGT   T  P 
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3189

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565
            +      VT T  P G +    T     T +  +P  +G           T  + P+  P
Sbjct: 3190 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3247

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T    P  T I  T  VTP T T   T    ++P+  +   T        Q  T+    T
Sbjct: 3248 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
             T+  P  T   + T T      + TT     T T T  ++P + P           + +
Sbjct: 3307 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3352

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744
                 P  T   T   +T P+T     T  P P GT     T      TT+  T   +G 
Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 3411

Query: 745  GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801
             T  T  I   ++V+P+ T  GT T   T I  +  +T       T +P   +PIT  TT
Sbjct: 3412 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3470

Query: 802  KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGTIL-R 847
               T       + T  P    T V    T  G Q        T   +   P   GT    
Sbjct: 3471 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3530

Query: 848  TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907
            T P+     VTP          TT  +  TT VT   T TGT +          T+  + 
Sbjct: 3531 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------TTTPIT 3581

Query: 908  TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967
            T  T   T     +Q    T IT +   T      G  TPT T  P++  T VT    P+
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3639

Query: 968  GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027
            G +         + + + TT  PT T T   +        T T+  +  P  T    TT 
Sbjct: 3640 GTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694

Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSNP------ 1078
              TTT V      P PT  Q          + VT T    G Q  +   + +        
Sbjct: 3695 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3751

Query: 1079 -PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137
             P  T    TT   TT T         +  P  T  T TT T T   +  G         
Sbjct: 3752 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3803

Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197
                 TP    I+  T        + +Q  T  T+  +TT TV  T  P           
Sbjct: 3804 -----TPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT---------- 3846

Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257
                G ++P    +   ++     +P+    P        +T   T +  G   P   P+
Sbjct: 3847 ----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310
                     +TT TVT       P+ T TQ  +  P  T  T T       T T TT+  
Sbjct: 3903 ---------TTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948

Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370
             +   V   P     +T TT   TT T+   T  P G Q P       T   T T T   
Sbjct: 3949 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4008

Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430
                   P  T++  T          P+ TP   T  + P PT      P      T TT
Sbjct: 4009 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068

Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQ 1489
             T T T T   +    P    +      +  G     T+    TTTV+ T T   T    
Sbjct: 4069 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4128

Query: 1490 STPVPGPSVPPPEELQVSPGPR-QQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVD 1548
            +TP+   +   P     +P P   Q P    + + +T     +        T  +     
Sbjct: 4129 TTPITTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4183

Query: 1549 LSSTGEPSSGQES----AGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMV 1604
            ++ T  P+  Q        +A +A +    PPP      + S PQ   + +   T +  +
Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPP------ESSTPQTSRSTSSPLTESTTL 4237

Query: 1605 TGLTPEELAVTAAAEAAAQAAAT 1627
                P  + +T+ A  +   A T
Sbjct: 4238 LSTLPPAIEMTSTAPPSTPTAPT 4260



 Score =  215 bits (548), Expect = 3e-55
 Identities = 304/1272 (23%), Positives = 415/1272 (32%), Gaps = 154/1272 (12%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            P T    T+ T  P P+       +  P      V P      T  P   P   TTTT+ 
Sbjct: 2586 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVT 2644

Query: 463  VLPTVPGSSISVPT-AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521
              PT  G+     T    T  V      TG Q  T TP+ T           VT T  P 
Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT--------TTTVTPTPTPT 2696

Query: 522  GVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580
            G +    T     T +  +P  +G           T  + P+  PT    P  T I  T 
Sbjct: 2697 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756

Query: 581  AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGT 640
             VTP T T   T    ++P+  +   T        Q  T+    T T+  P  T   + T
Sbjct: 2757 TVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2815

Query: 641  VTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ 700
             T      + TT     T T T  ++P + P           + +     P  T   T  
Sbjct: 2816 PTT---TPITTTTTVTPTPTPTGTQTPTTTP-----------ITTTTTVTPTPTPTGTQT 2861

Query: 701  ASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPT---ILGISSVS 757
             +T P+T    T  P P  T  +  T+     TT +T T        PT   I   ++V+
Sbjct: 2862 PTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2920

Query: 758  PSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITTKVMT-------SGTG 809
            P+ T  GT T   T I  +  +T       T +P   +PIT  TT   T       + T 
Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTT 2979

Query: 810  APAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGT-ILRTVPMGGVRLVTPVTV 862
             P    T V    T  G Q        T   +   P   GT    T P+     VTP   
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039

Query: 863  SAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQ 922
                   TT  +  TT VT   T TGT +          T+  + T  T   T     +Q
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTPTPTGTQ 3090

Query: 923  VINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSIL 982
                T IT +   T      G  TPT T  P++  T VT    P+G +         + +
Sbjct: 3091 TPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTP-----TTTPI 3143

Query: 983  ASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQ 1042
             + TT  PT T T   +        T T+  +  P  T    TT   TTT V      P 
Sbjct: 3144 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT---PT 3200

Query: 1043 PTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSN-------PPCETHETGTTNTAT 1092
            PT  Q          + VT T    G Q  +   + +         P  T    TT   T
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260

Query: 1093 TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVA 1152
            T T         +  P  T  T TT T T   +  G              TP    I+  
Sbjct: 3261 TTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------------TPTTTPITTT 3307

Query: 1153 TGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLA 1212
            T        + +  QT  T+  +TT TV  T  P               G ++P    + 
Sbjct: 3308 TTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP--------------TGTQTPTTTPIT 3351

Query: 1213 PLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTV 1272
              ++     +P+    P        +T   T +  G   P   P+         +TT TV
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI---------TTTTTV 3402

Query: 1273 TALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNAGSAQRVCSNPPCETH 1325
            T       P+ T TQ  +  P  T  T T       T T TT+   +   V   P     
Sbjct: 3403 TP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3457

Query: 1326 ETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHR 1385
            +T TT   TT T+   T  P G Q P       T   T T T          P  T++  
Sbjct: 3458 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3517

Query: 1386 TVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT-TVTSNMSSNQ 1444
            T          P+ TP   T  + P PT      P      T TT T T T T   +   
Sbjct: 3518 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------LTRAVTTVTQSTPVPG 1495
             P    +      +  G     T+    TTTV+ T          T  +TT T  TP P 
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637

Query: 1496 P-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGESAEVLSASQTPELPA 1545
            P       + P      V+P P     Q P    + + +T     +        T  +  
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697

Query: 1546 AVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVDQLS--LPQELMAEAQ 1596
               ++ T  P+  Q    + +  T  V P P       PT + +   +   P       Q
Sbjct: 3698 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3757

Query: 1597 AGTTTLMVTGLT 1608
              TTT + T  T
Sbjct: 3758 TPTTTPITTTTT 3769



 Score =  214 bits (545), Expect = 7e-55
 Identities = 305/1279 (23%), Positives = 418/1279 (32%), Gaps = 158/1279 (12%)

Query: 403  PATAATAT-SPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAP-------A 454
            P    T T +PT  P+ +     P         P   P+T    T+ P   P        
Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQTPTT 2611

Query: 455  PPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPV 514
             P TTT  V PT   +    PT   T  +     VT     TGT   T  P +      V
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTT--TTV 2666

Query: 515  TVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTVLSVPAG 573
            T T  P G +    T     T +  +P  +G           T  + P+  PT    P  
Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726

Query: 574  TTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPII 633
            T I  T  VTP T T   T    ++P+  +   T        Q  T+    T T+  P  
Sbjct: 2727 TPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2785

Query: 634  TVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQ 693
            T   + T T      + TT     T T T  ++P + P           + +     P  
Sbjct: 2786 TPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP-----------ITTTTTVTPTP 2831

Query: 694  TSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPT---I 750
            T   T   +T P+T    T  P P  T  +  T+     TT +T T        PT   I
Sbjct: 2832 TPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890

Query: 751  LGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITTKVMT---- 805
               ++V+P+ T  GT T   T I  +  +T       T +P   +PIT  TT   T    
Sbjct: 2891 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPTPTPT 2949

Query: 806  ---SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGT-ILRTVPMGGVR 855
               + T  P    T V    T  G Q        T   +   P   GT    T P+    
Sbjct: 2950 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3009

Query: 856  LVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGT 915
             VTP          TT  +  TT VT   T TGT +          T+  + T  T   T
Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPT 3060

Query: 916  IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVH 975
                 +Q    T IT +   T      G  TPT T  P++  T VT    P+G +     
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTP--- 3115

Query: 976  DLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVA 1035
                + + + TT  PT T T   +        T T+  +  P  T    TT   TTT V 
Sbjct: 3116 --TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3173

Query: 1036 NLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSN-------PPCETHET 1085
                 P PT  Q          + VT T    G Q  +   + +         P  T   
Sbjct: 3174 PT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230

Query: 1086 GTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPA 1145
             TT   TT T         +  P  T  T TT T T   +  G              TP 
Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------------TPT 3277

Query: 1146 VIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRS 1205
               I+  T        + +  QT  T+  +TT TV  T  P               G ++
Sbjct: 3278 TTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP--------------TGTQT 3321

Query: 1206 PAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGS 1265
            P    +   ++     +P+    P        +T   T +  G   P   P+        
Sbjct: 3322 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-------- 3373

Query: 1266 PSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNAGSAQRVCS 1318
             +TT TVT       P+ T TQ  +  P  T  T T       T T TT+   +   V  
Sbjct: 3374 -TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3427

Query: 1319 NPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLP 1378
             P     +T TT   TT T+   T  P G Q P       T   T T T          P
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487

Query: 1379 DATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT-TVT 1437
              T++  T          P+ TP   T  + P PT      P      T TT T T T T
Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3547

Query: 1438 SNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------LTRAVTTVT 1488
               +    P    +      +  G     T+    TTTV+ T          T  +TT T
Sbjct: 3548 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3607

Query: 1489 QSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGESAEVLSAS 1538
              TP P P       + P      V+P P     Q P    + + +T     +       
Sbjct: 3608 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3667

Query: 1539 QTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVDQLS--LPQ 1589
             T  +     ++ T  P+  Q    + +  T  V P P       PT + +   +   P 
Sbjct: 3668 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3727

Query: 1590 ELMAEAQAGTTTLMVTGLT 1608
                  Q  TTT + T  T
Sbjct: 3728 PTPTGTQTPTTTPITTTTT 3746



 Score =  213 bits (543), Expect = 1e-54
 Identities = 289/1203 (24%), Positives = 399/1203 (33%), Gaps = 149/1203 (12%)

Query: 403  PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455
            P T  T  +PTP P       + P     +  P       Q  T   IT      P P  
Sbjct: 3211 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3270

Query: 456  ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
                     P TTT  V PT   +    PT   T  +     VT     TGT   T  P 
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3327

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565
            +      VT T  P G +    T     T +  +P  +G           T  + P+  P
Sbjct: 3328 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3385

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T    P  T I  T  VTP T T   T    ++P+  +   T        Q  T+    T
Sbjct: 3386 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
             T+  P  T   + T T      + TT     T T T  ++P + P           + +
Sbjct: 3445 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3490

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744
                 P  T   T   +T P+T     T  P P GT     T      TT+  T   +G 
Sbjct: 3491 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 3549

Query: 745  GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801
             T  T  I   ++V+P+ T  GT T   T I  +  +T       T +P   +PIT  TT
Sbjct: 3550 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3608

Query: 802  KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGTIL-R 847
               T       + T  P    T V    T  G Q        T   +   P   GT    
Sbjct: 3609 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3668

Query: 848  TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907
            T P+     VTP          TT  +  TT VT   T TGT +          T+  + 
Sbjct: 3669 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------TTTPIT 3719

Query: 908  TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967
            T  T   T     +Q    T IT +   T      G  TPT T  P++  T VT    P+
Sbjct: 3720 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3777

Query: 968  GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027
            G +         + + + TT  PT T T   +        T T+  +  P  T    TT 
Sbjct: 3778 GTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832

Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSNP------ 1078
              TTT V      P PT  Q          + VT T    G Q  +   + +        
Sbjct: 3833 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889

Query: 1079 -PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137
             P  T    TT   TT T         +  P  T  T TT T T   +  G         
Sbjct: 3890 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3941

Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197
                 TP    I+  T        + +Q  T  T+  +TT TV  T  P           
Sbjct: 3942 -----TPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT---------- 3984

Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257
                G ++P    +   ++     +P+    P        +T   T +  G   P   P+
Sbjct: 3985 ----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310
                     +TT TVT       P+ T TQ  +  P  T  T T       T T TT+  
Sbjct: 4041 ---------TTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4086

Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370
             +   V   P     +T TT   TT T+   T  P G Q P       T   T T T   
Sbjct: 4087 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4146

Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430
                   P  T++  T          P+ TP   T  + P PT       P  T     T
Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-------PTGTQTGPPT 4199

Query: 1431 HTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQS 1490
            HT+T   + ++++  PP +++ Q    ++   + + T  S +   +  T T   +T T  
Sbjct: 4200 HTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAP 4259

Query: 1491 TPVPGPSV--PPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVD 1548
            T   G     PPP      PG     P R     +S+A    + +  + S     P  + 
Sbjct: 4260 TTTSGGHTLSPPPSTTTSPPG----TPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS 4315

Query: 1549 LSS 1551
              S
Sbjct: 4316 TPS 4318



 Score =  213 bits (541), Expect = 2e-54
 Identities = 307/1253 (24%), Positives = 412/1253 (32%), Gaps = 176/1253 (14%)

Query: 403  PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455
            P T  T  +PTP P       + P     +  P       Q  T   IT      P P  
Sbjct: 3142 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3201

Query: 456  ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
                     P TTT  V PT   +    PT   T  +     VT     TGT   T  P 
Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3258

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565
            +      VT T  P G +    T     T +  +P  +G           T  + P+  P
Sbjct: 3259 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3316

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T    P  T I  T  VTP T T   T    ++P+  +   T        Q  T+    T
Sbjct: 3317 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
             T+  P  T   + T T      + TT     T T T  ++P + P           + +
Sbjct: 3376 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 3421

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744
                 P  T   T   +T P+T     T  P P GT     T      TT+  T   +G 
Sbjct: 3422 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 3480

Query: 745  GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801
             T  T  I   ++V+P+ T  GT T   T I  +  +T       T +P   +PIT  TT
Sbjct: 3481 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 3539

Query: 802  KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGTIL-R 847
               T       + T  P    T V    T  G Q        T   +   P   GT    
Sbjct: 3540 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3599

Query: 848  TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907
            T P+     VTP          TT  +  TT VT   T TGT +          T+  + 
Sbjct: 3600 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---------TTTPIT 3650

Query: 908  TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967
            T  T   T     +Q    T IT +   T      G  TPT T  P++  T VT    P+
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3708

Query: 968  GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027
            G +         + + + TT  PT T T   +        T T+  +  P  T    TT 
Sbjct: 3709 GTQTPTT-----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763

Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSNP------ 1078
              TTT V      P PT  Q          + VT T    G Q  +   + +        
Sbjct: 3764 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3820

Query: 1079 -PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137
             P  T    TT   TT T         +  P  T  T TT T T   +  G         
Sbjct: 3821 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3872

Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197
                 TP    I+  T        + +Q  T  T+  +TT TV  T  P           
Sbjct: 3873 -----TPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPTPTPT---------- 3915

Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257
                G ++P    +   ++     +P+    P        +T   T +  G   P   P+
Sbjct: 3916 ----GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310
                     +TT TVT       P+ T TQ  +  P  T  T T       T T TT+  
Sbjct: 3972 ---------TTTTTVTPT-----PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017

Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370
             +   V   P     +T TT   TT T+   T  P G Q P       T   T T T   
Sbjct: 4018 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4077

Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430
                   P  T++  T          P+ TP   T  + P PT      P      T TT
Sbjct: 4078 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4137

Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQ 1489
             T T T T   +    P    +      +  G     T+    TTTV+ T T    T TQ
Sbjct: 4138 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---PTGTQ 4194

Query: 1490 STPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDL 1549
            + P    S  P  EL  S  P +   P Q  +S S+ L  ES  +LS      LP A+++
Sbjct: 4195 TGPPTHTSTAPIAELTTSNPPPESSTP-QTSRSTSSPLT-ESTTLLST-----LPPAIEM 4247

Query: 1550 SST-----------------------------GEPSSGQESAGSAVVATVVVQ 1573
            +ST                             G P+ G  +  S+      VQ
Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQ 4300



 Score =  212 bits (540), Expect = 3e-54
 Identities = 308/1287 (23%), Positives = 419/1287 (32%), Gaps = 165/1287 (12%)

Query: 403  PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455
            P T  T  +PTP P       + P     +  P       Q  T   IT      P P  
Sbjct: 2498 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2557

Query: 456  -----PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLV--TMRPASQ 508
                 PTTT I    TV  +    PT   TQ  P    +T     T TP    T  P + 
Sbjct: 2558 TGTQTPTTTPITTTTTVTPT----PTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTT 2612

Query: 509  --AGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565
                   VT T  P G +    T     T +  +P  +G           T  + P+  P
Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2672

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T    P  T I  T  VTP T T   T    ++P+  +   T        Q  T+    T
Sbjct: 2673 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
             T+  P  T   + T T      + TT     T T T  ++P + P           + +
Sbjct: 2732 TTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP-----------ITT 2777

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAG 745
                 P  T   T   +T P+T    T  P P  T  +  T+     TT +T T      
Sbjct: 2778 TTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2836

Query: 746  TKPT---ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801
              PT   I   ++V+P+ T  GT T   T I  +  +T       T +P   +PIT  TT
Sbjct: 2837 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 2895

Query: 802  KVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPGT-ILR 847
               T       + T  P    T V    T  G Q        T   +   P   GT    
Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955

Query: 848  TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLA 907
            T P+     VTP          TT  +  TT VT   T TGT +          T+  + 
Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPIT 3006

Query: 908  TPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS 967
            T  T   T     +Q    T IT +   T      G  TPT T  P++  T VT    P+
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPT 3064

Query: 968  GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTN 1027
            G +         + + + TT  PT T T   +        T T+  +  P  T    TT 
Sbjct: 3065 GTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119

Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRVCSN------- 1077
              TTT V      P PT  Q          + VT T    G Q  +   + +        
Sbjct: 3120 ITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176

Query: 1078 PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137
             P  T    TT   TT T         +  P  T  T TT T T   +  G         
Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQ------- 3228

Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM 1197
                 TP    I+  T        + +  QT  T+  +TT TV  T  P           
Sbjct: 3229 -----TPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP----------- 3270

Query: 1198 AREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257
                G ++P    +   ++     +P+    P        +T   T +  G   P   P+
Sbjct: 3271 ---TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNA 1310
                     +TT TVT       P+ T TQ  +  P  T  T T       T T TT+  
Sbjct: 3328 ---------TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3373

Query: 1311 GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS 1370
             +   V   P     +T TT   TT T+   T  P G Q P       T   T T T   
Sbjct: 3374 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3433

Query: 1371 VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430
                   P  T++  T          P+ TP   T  + P PT      P      T TT
Sbjct: 3434 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3493

Query: 1431 HTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------L 1480
             T T T T   +    P    +      +  G     T+    TTTV+ T          
Sbjct: 3494 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3553

Query: 1481 TRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGE 1530
            T  +TT T  TP P P       + P      V+P P     Q P    + + +T     
Sbjct: 3554 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3613

Query: 1531 SAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVD 1583
            +        T  +     ++ T  P+  Q    + +  T  V P P       PT + + 
Sbjct: 3614 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3673

Query: 1584 QLS--LPQELMAEAQAGTTTLMVTGLT 1608
              +   P       Q  TTT + T  T
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTT 3700



 Score =  207 bits (526), Expect = 1e-52
 Identities = 299/1240 (24%), Positives = 408/1240 (32%), Gaps = 156/1240 (12%)

Query: 438  QPLTQVGITLLPQAAPAPPTTT----TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQ 493
            QP T   +T      P PPTTT    T  V PT   +    PT   T  +     VT   
Sbjct: 1881 QPTT---MTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTP 1934

Query: 494  ATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAA 552
              TGT   T  P +      VT T  P G +    T     T +  +P  +G        
Sbjct: 1935 TPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992

Query: 553  AAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKT 612
               T  + P+  PT    P  T I  T  VTP T T   T    ++P+  +   T     
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTP 2051

Query: 613  AAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPG 672
               Q  T+    T T+  P  T   + T T      + TT     T T T  ++P + P 
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVTPTPTPTGTQTPTTTP- 2107

Query: 673  GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP 732
                      + +     P  T   T   +T P+T    T  P P  T  +  T+     
Sbjct: 2108 ----------ITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGTQTPTTTPITT 2156

Query: 733  TTIITTTQASGAGTKPT---ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTS 788
            TT +T T        PT   I   ++V+P+ T  GT T   T I  +  +T       T 
Sbjct: 2157 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2216

Query: 789  SPGIKSPITIITTKVMT-------SGTGAPAKIITAVPKIATGHGQQG------VTQVVL 835
            +P   +PIT  TT   T       + T  P    T V    T  G Q        T   +
Sbjct: 2217 TP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2275

Query: 836  KGAPGQPGT-ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSL 894
               P   GT    T P+     VTP          TT  +  TT VT   T TGT +   
Sbjct: 2276 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--- 2332

Query: 895  AGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPV 954
                   T+  + T  T   T     +Q    T IT +   T      G  TPT T  P+
Sbjct: 2333 ------PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PI 2384

Query: 955  SQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCS 1014
            +  T VT    P+G +         + + + TT  PT T T   +        T T+  +
Sbjct: 2385 TTTTTVTPTPTPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2439

Query: 1015 NPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSV 1071
              P  T    TT   TTT V      P PT  Q          + VT T    G Q  + 
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496

Query: 1072 VRVCSN-------PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAM 1124
              + +         P  T    TT   TT T         +  P  T  T TT T T   
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTP 2555

Query: 1125 SSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATG 1184
            +  G              TP    I+  T        + +  QT  T+  +TT TV  T 
Sbjct: 2556 TPTGTQ------------TPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTP 2601

Query: 1185 APCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTR 1244
             P               G ++P    +   ++     +P+    P        +T   T 
Sbjct: 2602 TP--------------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647

Query: 1245 SSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT--- 1301
            +  G   P   P+         +TT TVT       P+ T TQ  +  P  T  T T   
Sbjct: 2648 TPTGTQTPTTTPI---------TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTP 2693

Query: 1302 ----TNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPC 1357
                T T TT+   +   V   P     +T TT   TT T+   T  P G Q P      
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2753

Query: 1358 ETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVC 1417
             T   T T T          P  T++  T          P+ TP   T  + P PT    
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813

Query: 1418 SNPPCETHETGTTHTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV 1476
              P      T TT T T T T   +    P    +      +  G     T+    TTTV
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2873

Query: 1477 SST---------LTRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPR 1517
            + T          T  +TT T  TP P P       + P      V+P P     Q P  
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933

Query: 1518 QLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP- 1576
              + + +T     +        T  +     ++ T  P+  Q    + +  T  V P P 
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993

Query: 1577 ------PTQSEVDQLS--LPQELMAEAQAGTTTLMVTGLT 1608
                  PT + +   +   P       Q  TTT + T  T
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3033



 Score =  196 bits (497), Expect = 3e-49
 Identities = 309/1297 (23%), Positives = 425/1297 (32%), Gaps = 209/1297 (16%)

Query: 403  PATAATATSPTPNPVPSV-----------PANPPKSPAPAAAAPAVQPLTQVGITLLPQA 451
            P T  T   PT  P P +           P+ P  +P+P    P+  P T    T  P  
Sbjct: 1441 PITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPS--PPTTTTTTPPPTT 1498

Query: 452  APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVT--MRPASQA 509
             P+PPTTT I    T P S+ ++P    T   P     T P  TT +P  T  + P +  
Sbjct: 1499 TPSPPTTTPI----TPPASTTTLPPTT-TPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553

Query: 510  GKAPVTVTSLPAGVRMVVP----TQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565
               P T T  P       P    T S   T   S P ++           T   PP++ P
Sbjct: 1554 TTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTIT-----------TTTPPPTTTP 1602

Query: 566  ----TVLSVPAGTTIVKTMAVTP-----GTTTLPATVKVASSPVMVSNPATRMLKTAAAQ 616
                T  + P  TT       TP      TTTLP T   +  P   + P           
Sbjct: 1603 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT-------- 1654

Query: 617  VGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSAL 676
              T+ S  T T+  P IT   +   T    + + TT     T   T   SP + P     
Sbjct: 1655 --TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTT--PSPTTTP----- 1705

Query: 677  ISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736
                        + P+ T+  T  ++T P         P P        T+    PTT +
Sbjct: 1706 ------------SSPI-TTTTTPSSTTTP--------SPPPTTMTTPSPTTTPSPPTTTM 1744

Query: 737  TTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSS--PGIKS 794
            TT   +   T  + L  + + PS T P  +    T P +  +     TG   S  P    
Sbjct: 1745 TTLPPT---TTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHK 1801

Query: 795  PITIITTKVMTSGTGAPAKI---ITAVPKIATGH-GQQGVTQV----VLKGAPGQPGTIL 846
            P           G G  A I    T  P +  G  GQ  V  V    + K    +PG + 
Sbjct: 1802 PGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV- 1860

Query: 847  RTVPMG-----GVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHS 901
              +PM       + +     V+      TT     T   TT  T T TV+ +    G   
Sbjct: 1861 --IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTG--- 1915

Query: 902  TSASLATPITTLGTI----ATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQP 957
            T     TPITT  T+        +Q    T IT +   T      G  TPT T  P++  
Sbjct: 1916 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTT 1973

Query: 958  TQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPP 1017
            T VT    P+G +         + + + TT  PT T T   +        T T+  +  P
Sbjct: 1974 TTVTPTPTPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2028

Query: 1018 CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST---VGQQNGSVVRV 1074
              T    TT   TTT V      P PT  Q          + VT T    G Q  +   +
Sbjct: 2029 TGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2085

Query: 1075 CSN-------PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSV 1127
             +         P  T    TT   TT T         +  P  T  T TT T T   +  
Sbjct: 2086 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPT 2144

Query: 1128 GANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPC 1187
            G              TP    I+  T        + +  QT  T+  +TT TV  T  P 
Sbjct: 2145 GTQ------------TPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP- 2189

Query: 1188 SAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSV 1247
                          G ++P    +   ++     +P+    P        +T   T +  
Sbjct: 2190 -------------TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2236

Query: 1248 GAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT------ 1301
            G   P   P+         +TT TVT       P+ T TQ  +  P  T  T T      
Sbjct: 2237 GTQTPTTTPI---------TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPT 2282

Query: 1302 -TNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH 1360
             T T TT+   +   V   P     +T TT   TT T+   T  P G Q P       T 
Sbjct: 2283 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2342

Query: 1361 QTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNP 1420
              T T T          P  T++  T          P+ TP   T  + P PT      P
Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2402

Query: 1421 PCETHETGTTHTAT-TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST 1479
                  T TT T T T T   +    P    +      +  G     T+    TTTV+ T
Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2462

Query: 1480 ---------LTRAVTTVTQSTPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLL 1520
                      T  +TT T  TP P P       + P      V+P P     Q P    +
Sbjct: 2463 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522

Query: 1521 QSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP---- 1576
             + +T     +        T  +     ++ T  P+  Q    + +  T  V P P    
Sbjct: 2523 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2582

Query: 1577 ---PTQSEVDQLS--LPQELMAEAQAGTTTLMVTGLT 1608
               PT + +   +   P       Q  TTT + T  T
Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2619



 Score =  130 bits (326), Expect = 2e-29
 Identities = 213/978 (21%), Positives = 312/978 (31%), Gaps = 120/978 (12%)

Query: 712  TKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKT 771
            T  P P  T     T+    PTT  TT   +   + P  +  ++  P TT P       T
Sbjct: 1405 TPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP--ITTTTTPPPTTTPSPPISTTT 1462

Query: 772  IPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVT 831
             P          T  +      SP T  TT    + T +P       P  +T       T
Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST-------T 1515

Query: 832  QVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVS 891
             +     P  P T   T P       +P T + + P  +T  +  TT  +   T T T  
Sbjct: 1516 TLPPTTTPSPPTTTTTTPP--PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT-- 1571

Query: 892  TSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPT-IT 950
                       + + + P TT  +  T+++    PT  T S   TT T     TTP+  T
Sbjct: 1572 --------PPPTTTPSPPTTTTPSPPTITTTTPPPTT-TPSPPTTTTTTPPPTTTPSPPT 1622

Query: 951  MQPVSQPTQVTLI---TAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPG 1007
              P++ PT  T +   T PS          P +  + PTT  P+  +T   +      P 
Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS 1682

Query: 1008 TVTLVCSNPPCETHETGTTNTA-----TTTVVANLGGHPQPTQVQFVCDRQEAAASLVTS 1062
            +      +PP  T  T +  T      TTT   +    P P              S  T+
Sbjct: 1683 SPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTT 1742

Query: 1063 TV----GQQNGSVVRVCSNPPCETHETGTTNTATTATS------NMAGQHGCSNPPCETH 1112
            T+         S +     PP  T  T +  + TT T+      N  G      P    H
Sbjct: 1743 TMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKP--NFH 1800

Query: 1113 ETGTTNTATTAMSSVGANHQRDARRACAAGTP-----AVIRISVATGALEAAQGSK---- 1163
            + G        +   G       R       P       +   V+ G +   +  K    
Sbjct: 1801 KPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860

Query: 1164 ---------------SQCQTRQTSATSTTM--TVMATGAPCSAGPLLGPSMAREPGGRSP 1206
                            +C T+ T+ T+TT       T  P +    + P+     G ++P
Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPT-PTPTGTQTP 1919

Query: 1207 AFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSP 1266
                +   ++     +P+    P        +T   T +  G   P   P+         
Sbjct: 1920 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI--------- 1970

Query: 1267 STTVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNAGSAQRVCSN 1319
            +TT TVT       P+ T TQ  +  P  T  T T       T T TT+   +   V   
Sbjct: 1971 TTTTTVTP-----TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2025

Query: 1320 PPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPD 1379
            P     +T TT   TT T+   T  P G Q P       T   T T T          P 
Sbjct: 2026 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2085

Query: 1380 ATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT-TVTS 1438
             T++  T          P+ TP   T  + P PT      P      T TT T T T T 
Sbjct: 2086 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2145

Query: 1439 NMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST---------LTRAVTTVTQ 1489
              +    P    +      +  G     T+    TTTV+ T          T  +TT T 
Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205

Query: 1490 STPVPGP-------SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGESAEVLSASQ 1539
             TP P P       + P      V+P P     Q P    + + +T     +        
Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2265

Query: 1540 TPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVDQLS--LPQE 1590
            T  +     ++ T  P+  Q    + +  T  V P P       PT + +   +   P  
Sbjct: 2266 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2325

Query: 1591 LMAEAQAGTTTLMVTGLT 1608
                 Q  TTT + T  T
Sbjct: 2326 TPTGTQTPTTTPITTTTT 2343



 Score =  105 bits (261), Expect = 6e-22
 Identities = 137/564 (24%), Positives = 194/564 (34%), Gaps = 62/564 (10%)

Query: 403  PATAATATSPTPNPV-----PSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP-- 455
            P T  T  +PTP P       + P     +  P       Q  T   IT      P P  
Sbjct: 3786 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3845

Query: 456  ---------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
                     P TTT  V PT   +    PT   T  +     VT     TGT   T  P 
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPI 3902

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAP 565
            +      VT T  P G +    T     T +  +P  +G           T  + P+  P
Sbjct: 3903 TTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3960

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T    P  T I  T  VTP T T   T    ++P+  +   T        Q  T+    T
Sbjct: 3961 TGTQTPTTTPITTTTTVTP-TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4019

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
             T+  P  T   + T T      + TT     T T T  ++P + P           + +
Sbjct: 4020 TTTVTPTPTPTGTQTPTTTP---ITTTTTVTPTPTPTGTQTPTTTP-----------ITT 4065

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGA 744
                 P  T   T   +T P+T     T  P P GT     T      TT+  T   +G 
Sbjct: 4066 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-TTTTVTPTPTPTGT 4124

Query: 745  GTKPT--ILGISSVSPSTTKPGTTTIIKT-IPMSAIITQAGATGVTSSPGIKSPITIITT 801
             T  T  I   ++V+P+ T  GT T   T I  +  +T       T +P   +PIT  TT
Sbjct: 4125 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTT 4183

Query: 802  KVMT-----SGTGAPAKIITA-VPKIATGHGQQGVTQVVLKGAPGQP----GTILRTVPM 851
               T     + TG P    TA + ++ T +     +      +   P     T+L T+P 
Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPP 4243

Query: 852  GGVRLVTPVTVSAVKPAVT----TLVVKGTT-----GVTTLGTVTGTVSTSLAGAGGHST 902
                  T    +   P  T    TL    +T     G  T GT TG+ S         +T
Sbjct: 4244 AIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 4303

Query: 903  SASLATPITTLGTIATLSSQVINP 926
            +++     T L T + + +  + P
Sbjct: 4304 TSAWTPTPTPLSTPSIIRTTGLRP 4327



 Score = 97.8 bits (242), Expect = 9e-20
 Identities = 186/848 (21%), Positives = 262/848 (30%), Gaps = 96/848 (11%)

Query: 839  PGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAG 898
            P  P T     P     L  P T +   P  TT     TT  +   T T T   +   + 
Sbjct: 1399 PSPPTTTPSPPPTSTTTL--PPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 899  GHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPT 958
              ST+ +   P TT     T  S    P   T S   TT T     TTP+        P 
Sbjct: 1457 PISTTTT-PPPTTTPSPPTTTPS----PPTTTPSPPTTTTTTPPPTTTPS--------PP 1503

Query: 959  QVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPC 1018
              T IT P+     P    P     + TT  PT T +   +        T TL  +  P 
Sbjct: 1504 TTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1563

Query: 1019 ETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNP 1078
                T TT   TTT        P P  +           S  T+T      +      +P
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT---PSP 1620

Query: 1079 PCETHETGTTNTAT---TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDA 1135
            P  T  T  T+T T   T T +       + PP  T    TT T +  +++         
Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT 1680

Query: 1136 RRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATS-----TTMT----VMATGAP 1186
              +    TP+    ++ T +      S     T  +S T+     TTMT          P
Sbjct: 1681 PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPP 1740

Query: 1187 CSAGPLLGPSMAREPGGRSPAFVQLAPLS-SKVRLSSPSIKDLPAGRHSHAVSTAAMTRS 1245
             +    L P+    P   +P    + P + S    ++P+   +P    +  + +      
Sbjct: 1741 TTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFH 1800

Query: 1246 SVGAGEPRMAPVC---------------ESLQGGSPSTTVTVTALEALLC------PSAT 1284
              G     +  VC                 +  G    TV       L+C      P   
Sbjct: 1801 KPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860

Query: 1285 VTQV-CSN-------PPCETHETGTTNTA-------TTSNAGSAQRVCSNPPCETHETGT 1329
            +    C N         C T  T  T T        TT+   +   V   P     +T T
Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPT 1920

Query: 1330 THTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVES 1389
            T   TT T+   T  P G Q P       T   T T T          P  T++  T   
Sbjct: 1921 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1980

Query: 1390 GLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT-TVTSNMSSNQDPPP 1448
                   P+ TP   T  + P PT      P      T TT T T T T   +    P  
Sbjct: 1981 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2040

Query: 1449 AASDQGEVESTQGDSVNITSSSAITTTVSST---------LTRAVTTVTQSTPVPGP--- 1496
              +      +  G     T+    TTTV+ T          T  +TT T  TP P P   
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2100

Query: 1497 ----SVPPPEELQVSPGPR---QQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDL 1549
                + P      V+P P     Q P    + + +T     +        T  +     +
Sbjct: 2101 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2160

Query: 1550 SSTGEPSSGQESAGSAVVATVVVQPPP-------PTQSEVDQLS--LPQELMAEAQAGTT 1600
            + T  P+  Q    + +  T  V P P       PT + +   +   P       Q  TT
Sbjct: 2161 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2220

Query: 1601 TLMVTGLT 1608
            T + T  T
Sbjct: 2221 TPITTTTT 2228



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 72/382 (18%), Positives = 107/382 (28%), Gaps = 26/382 (6%)

Query: 1435 TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT---TVTQST 1491
            T  S  ++   PPP ++      +T       T++   TTT S  +T   T   T T S 
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 1492 PVPGPSVPPPEELQVSPGPRQQLP-PRQLLQSASTALMGESAEVLSASQTPELPAAVDLS 1550
            P+   + PPP     +P P    P P     S  T          + S     P     S
Sbjct: 1457 PISTTTTPPP---TTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513

Query: 1551 STGEPSSGQESAGSAVVAT--VVVQPPPPTQSEV----DQLSLPQELMAEAQAGTTTLMV 1604
            +T  P +   S  +    T      P PPT + +       +LP          TTT   
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1573

Query: 1605 TGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQ 1664
               TP     T  +               +                 P  T     T T 
Sbjct: 1574 PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1633

Query: 1665 AELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSL- 1723
                  +        TT P   T            +            P     P+  + 
Sbjct: 1634 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT-------PPPTTTPSSPIT 1686

Query: 1724 NDPAIESNCLNELAGTV----PSTVALLPSTATESLAPSNTFVAPQPVVVAS-PAKLQAA 1778
              P+  +  +   + T     P T    PS+ T    P  T   P P    S P      
Sbjct: 1687 TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT 1746

Query: 1779 ATLTEVANGIESLGVKPDLPPP 1800
               T  ++ + +  + P + PP
Sbjct: 1747 LPPTTTSSPLTTTPLPPSITPP 1768



 Score = 33.9 bits (76), Expect = 1.7
 Identities = 38/132 (28%), Positives = 56/132 (42%), Gaps = 22/132 (16%)

Query: 359  LETEKPPPPARV-QLVRANTNSLEVSWGAVATADSYLLQLQKYDIPAT--AATATSP--T 413
            L T  PPP +   Q  R+ ++ L  S   ++T     +++     P+T  A T TS   T
Sbjct: 4209 LTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPP-AIEMTSTAPPSTPTAPTTTSGGHT 4267

Query: 414  PNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPT--TTTIQVLPTVPGSS 471
             +P PS   +PP +P               G T    +AP P T  TTT       P + 
Sbjct: 4268 LSPPPSTTTSPPGTPTR-------------GTTTGSSSAPTPSTVQTTTTSAWTPTP-TP 4313

Query: 472  ISVPTAARTQGV 483
            +S P+  RT G+
Sbjct: 4314 LSTPSIIRTTGL 4325


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score =  189 bits (480), Expect = 2e-47
 Identities = 367/1777 (20%), Positives = 615/1777 (34%), Gaps = 244/1777 (13%)

Query: 379  SLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQ 438
            S+ VS   VA+ ++  L     D  +   T+T  + +P P+   + P S       P   
Sbjct: 1635 SIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTP--- 1691

Query: 439  PLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSI----SVPTAARTQGVPAVLKVTGPQA 494
             LT + +   P A+ A  T +T  V  + P ++     S PT +    +P      G   
Sbjct: 1692 -LTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTP 1750

Query: 495  TTGTPLVTM----RPASQAGKAPV-TVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAAL 549
             T  P+ T       AS     P+ T T +           +A+GT I +S    GM  L
Sbjct: 1751 LTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPL 1810

Query: 550  AAAAAATQKIPPSSAPTVLSVP--AGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPAT 607
             +   +   +  S A T+ + P  + + +V + AV+   T    T    S+P    +  +
Sbjct: 1811 TSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTP----SEGS 1866

Query: 608  RMLKTAAAQVGTSVSSATNT-STRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT---- 662
              L +      T  SS TNT ST P +T   +   T AQ +   TT  G    T T    
Sbjct: 1867 TALTSIPVSTTTVASSETNTLSTTPAVT--STPVTTYAQVSSSPTTADGSSMPTSTPREG 1924

Query: 663  ---LVKSPISVPG-GSALISNLGKVMSVVQTKPVQT------SAVTGQASTGPVTQIIQT 712
               L   P+S     S+ I+ L   ++  +T PV T      S  T   ++ P     + 
Sbjct: 1925 RPPLTSIPVSTTTVASSEINTLSTTLADTRT-PVTTYSQASSSPTTADGTSMPTPAYSEG 1983

Query: 713  KGPL---PAGTILKLVTSADGKPTTIITT----TQASGAGTKPTILGISSVSPSTTKPGT 765
              PL   P  T L + + A    TT + T    T ++   + PT  G +S+  ST    T
Sbjct: 1984 STPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERT 2043

Query: 766  TTII-KTIPMSAIITQAG----------ATGVTSSPGIKSPITIITTKVMTSGTGAPAKI 814
            T +    +  + +++  G           T VT+S    S  T   + +  S     + +
Sbjct: 2044 TPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPL 2103

Query: 815  ITAVPKIAT---------------GHGQQGVTQVVLKGAP-GQPGTILRTVPMGGVRL-V 857
            +T++P   T                     +T   +  +P    GT ++T      R  +
Sbjct: 2104 LTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPL 2163

Query: 858  TPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIA 917
            T + VS    A + +    TT V T   VT +     +      TS   +TP  + G+  
Sbjct: 2164 TSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTP--SEGSTP 2221

Query: 918  TLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQ---PV 974
              S  V     +T  A+  + T     T  T + +  S PT     + P+   ++   P+
Sbjct: 2222 FTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPL 2281

Query: 975  HDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVV 1034
              +PVS      +E  T + T  DS      P T +   S+PP      GT+   +T+  
Sbjct: 2282 TSIPVSHTLVANSEVSTLSTTPVDSNT----PFTTSTEASSPPPTAE--GTSMPTSTSSE 2335

Query: 1035 ANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNP--------PCETHETG 1086
             N      P     V   + +  S   +       +  +  S+P        P  T+  G
Sbjct: 2336 GNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEG 2395

Query: 1087 TTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAA----- 1141
            +T   +   S M       +    TH T   +T+T   +S  A+         +      
Sbjct: 2396 STPLTSVPVSTMP----VVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPP 2451

Query: 1142 --GTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAR 1199
              GT  +  + V+T  + +++          TS   TT T  A+ +P +A  ++ P    
Sbjct: 2452 SEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTE-ASSSPTTAEDIVVPISTA 2510

Query: 1200 EPGGR--SPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257
              G    +   V   P++S     + ++   P   +S  V++  ++ S+  A E    P 
Sbjct: 2511 SEGSTLLTSIPVSTTPVASP---EASTLSTTPVDSNSPVVTSTEISSSATSA-EGTSMPT 2566

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVC 1317
                +G +P  ++ V+        ++T+    S  P +T    TT+T T+S+  +A+   
Sbjct: 2567 STYSEGSTPLRSMPVSTKPLASSEASTL----STTPVDTSIPVTTSTETSSSPTTAKD-- 2620

Query: 1318 SNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSV--GA 1375
            ++ P  T    +T   +   S       E            T  TTSTGT+ S +   G+
Sbjct: 2621 TSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGS 2680

Query: 1376 LLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATT 1435
             +P +T   R+          P       T LLA         N    T  T    T+T 
Sbjct: 2681 SMPTSTPGERST---------PLTNILVSTTLLA---------NSEASTLSTTPVDTSTP 2722

Query: 1436 VTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVP- 1494
            VT++  ++  P  A      + +    S  +TS    T  V+S+    V+T    T +P 
Sbjct: 2723 VTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPV 2782

Query: 1495 -----GPSVPPPEELQVSP--GPRQQLPPRQLLQSASTALMGESAEVLSASQT-PELPAA 1546
                   S P   E+   P   P +   P   +    T +    A  LS +      P  
Sbjct: 2783 TTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVT 2842

Query: 1547 VDLSSTGEPSSGQ--------ESAGSAVVATVVVQPPPPTQSEVDQL-------SLPQEL 1591
                ++  P++ +         S GS ++ ++ V   P   SE   L       S+P   
Sbjct: 2843 TSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTT 2902

Query: 1592 MAEAQAGTTTLMVTGL---TPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMG 1648
              E  +  TT   T +   TP E++                  ++ +  V  A  +A   
Sbjct: 2903 STEGSSSPTTAEGTSMPISTPSEVSTPLT--------------SILVSTVPVAGSEASTL 2948

Query: 1649 TGEPMDTSEAAATVTQAELGHLSAEG---------------QEGQATTIPIVLTQQELAA 1693
            +  P+DT     T  +A     +AEG                    +T+P+  ++    +
Sbjct: 2949 STTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLS 3008

Query: 1694 LVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATE 1753
                          +    PT A      ++ P+  S  L  +   V +T   +P  +T 
Sbjct: 3009 RTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSI--PVSTTPVAIPEASTL 3066

Query: 1754 SLAP--SNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQ 1811
            S  P  SN+ V     V +SP   +     T +     S G  P    P S  P      
Sbjct: 3067 STTPVDSNSPVVTSTEVSSSPTPAEG----TSMPISTYSEGSTPLTGVPVSTTP------ 3116

Query: 1812 WFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGTAYKFRVAGINA 1871
                         VT   +      P D                   GT+          
Sbjct: 3117 -------------VTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSM--------- 3154

Query: 1872 CGRGPFSEISAFKTCLPGFPGAPCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQS 1931
                P S  S   T L   P +   +  S+       T     V +   +  S      +
Sbjct: 3155 ----PTSTPSEGSTPLTYMPVSTMLVVSSEDS-----TLSATPVDTSTPVTTSTEATSST 3205

Query: 1932 SQAGGELKSSTPAQ--LAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAIIFRIAARNEK 1989
            +  G  + +STP++       V    +P    ++S LS   +D  T       +    E 
Sbjct: 3206 TAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP------LTTSTEA 3259

Query: 1990 GYGPATQVRWLQETSKDSSGTKPANKRPMSSPEMKSA 2026
               P T       TS  S G+ P    P+S+  + S+
Sbjct: 3260 SSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASS 3296



 Score =  187 bits (475), Expect = 9e-47
 Identities = 320/1475 (21%), Positives = 545/1475 (36%), Gaps = 213/1475 (14%)

Query: 379  SLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQ 438
            S+ VS   V T+++  L     D      T+T  T +P  +   + P S       P   
Sbjct: 2224 SMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTS 2283

Query: 439  -PLTQV--------GITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV 489
             P++           ++  P  +  P TT+T    P       S+PT+  ++G   + ++
Sbjct: 2284 IPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRM 2343

Query: 490  TGPQATT-----------GTPLVTMRPA---SQAGKAPVTV--TSLPAGVRMVVPTQSAQ 533
              P +TT            TP  T  P    SQAG +P T   TS+P        T S  
Sbjct: 2344 --PVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTS------TYSEG 2395

Query: 534  GTVIGSSPQMSGMAALAAAAAATQKIP-PSSAPTVLSVPAGT-------TIVKTMAVTPG 585
             T + S P +S M  +++ A+     P  +S P   S  A +       T + T   + G
Sbjct: 2396 STPLTSVP-VSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG 2454

Query: 586  TTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQ 645
            TT L A++ V+++PV+ S   T  L T      T ++++T  S+ P         ++ A 
Sbjct: 2455 TTPL-ASMPVSTTPVVSSEAGT--LSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTAS 2511

Query: 646  QAQVVTTVVGGVTKTITLVKSPISVPGGSALISN-LGKVMSVVQTKPVQTSAVTGQASTG 704
            +   + T       +I +  +P++ P  S L +  +     VV +  + +SA + + ++ 
Sbjct: 2512 EGSTLLT-------SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSM 2564

Query: 705  PVTQIIQTKGPLPAGTI-LKLVTSADGK-----------PTTIITTTQASGAGTKPTILG 752
            P +   +   PL +  +  K + S++             P T  T T +S    K T + 
Sbjct: 2565 PTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMP 2624

Query: 753  ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPA 812
            IS+ S  +T   T+ ++ T+P+++    + A+ ++++P       + T  ++T+ TG  +
Sbjct: 2625 ISTPSEVSTSL-TSILVSTMPVAS----SEASTLSTTP-------VDTRTLVTTSTGTSS 2672

Query: 813  KIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTL 872
                  P  A G      T       PG+     R+ P+  + + T +  ++    ++T 
Sbjct: 2673 S-----PTTAEGSSMPTST-------PGE-----RSTPLTNILVSTTLLANSEASTLSTT 2715

Query: 873  VVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTL--GTIATLSSQV--INPTA 928
             V  +T VTT    + + +T+   +   ST +  +TP+T++   T+   SS+   ++ TA
Sbjct: 2716 PVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTA 2775

Query: 929  ITVSAAQTTLT-AAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPT- 986
            +  S   TT T A+   TT  +T  P S P++ +       V   PV       L++   
Sbjct: 2776 VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPV 2835

Query: 987  -TEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTT-----NTATTTVVANLGGH 1040
             T  P  T T A S     +   V       P  T   G+T       +TT V ++    
Sbjct: 2836 DTSTPVTTSTKASSSPTTAEGIVV-------PISTASEGSTLLTSIPVSTTPVASSEAST 2888

Query: 1041 PQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTAT-TATSNMA 1099
               T V       + +  + TST G  + +     S P     E  T  T+   +T  +A
Sbjct: 2889 LSTTPV-------DTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVA 2941

Query: 1100 GQHGC--SNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVAT---G 1154
            G      S  P +T    TT+   ++  +                TP +  +SV+T    
Sbjct: 2942 GSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTP-LTSMSVSTMPVA 3000

Query: 1155 ALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPL 1214
            + EA+  S++   T     TST  +   T A  +  P+  PS    P    P  V   P+
Sbjct: 3001 SSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIP--VSTTPV 3058

Query: 1215 SSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTA 1274
            +      + ++   P   +S  V++  ++ S   A E    P+    +G +P T V V+ 
Sbjct: 3059 AIP---EASTLSTTPVDSNSPVVTSTEVSSSPTPA-EGTSMPISTYSEGSTPLTGVPVST 3114

Query: 1275 LEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTAT 1334
                   +++     S  P +T    TT+T                  E H + TT   T
Sbjct: 3115 TPV----TSSAISTLSTTPVDTSTPVTTST------------------EAHSSPTTSEGT 3152

Query: 1335 TATSNGGTGQPEGGQQPPAGRPCETHQTTST--GTTMSVSVGALLPDATSSHRTVESGLE 1392
            +      T  P  G  P    P  T    S+   T  +  V    P  TS+  T  +  E
Sbjct: 3153 SMP----TSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAE 3208

Query: 1393 VAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTA-----TTVTSNMSSNQDPP 1447
              + P+ TP  G   L   P     SN P  + E     T      T +T++  ++  PP
Sbjct: 3209 GTSIPTSTPSEGMTPLTSVPV----SNTPVASSEASILSTTPVDSNTPLTTSTEASSSPP 3264

Query: 1448 PAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVP------GPSVPPP 1501
             A        +    S  +TS    TTTV+S+ T  ++T    T  P        S PP 
Sbjct: 3265 TAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPI 3324

Query: 1502 EELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQES 1561
             +    P          L   + +     S+E  + S TP     VD +ST   +S + S
Sbjct: 3325 ADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTP-----VD-TSTPVTTSTEAS 3378

Query: 1562 AGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAA 1621
                      +    P++      S+P        +   TL  T +    L VT + EA+
Sbjct: 3379 LSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTL-VTTSTEAS 3437

Query: 1622 AQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATT 1681
            +     E                   GT  P  T+   +T                  +T
Sbjct: 3438 SSPTIAE-------------------GTSLPTSTTSEGSTPLSIM-----------PLST 3467

Query: 1682 IPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVP 1741
             P+  ++    +                +  PT A   +   +     S  L  +  +  
Sbjct: 3468 TPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTT 3527

Query: 1742 STVALLPSTATESLAPSNTFVAPQPVVVASPAKLQ 1776
               +   ST + +   SNTFV       +SPA LQ
Sbjct: 3528 PVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQ 3562



 Score =  177 bits (450), Expect = 7e-44
 Identities = 351/1572 (22%), Positives = 579/1572 (36%), Gaps = 234/1572 (14%)

Query: 379  SLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVP----SVPANPP-KSPAPAAA 433
            S+  S   V ++++  L     D      T+T  T +P      S+P + P +   P  +
Sbjct: 928  SMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTS 987

Query: 434  APAVQPLTQVG----ITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV 489
             P    L        ++  P  +  P TT+T    P       S+PT+  ++G   + ++
Sbjct: 988  TPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRM 1047

Query: 490  ----------------TGPQATTGTPLVTMRPASQAG--------------KAPVTVTSL 519
                            T P A T TP+ T   AS +               +    +TS+
Sbjct: 1048 PVSTTMVASSETSTLSTTP-ADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSV 1106

Query: 520  PAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKI----------PPSSAPTVL- 568
            P   R+VV   S++ + + ++P  + +    +  A++             PPS   T L 
Sbjct: 1107 PVSTRLVV---SSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLA 1163

Query: 569  SVPAGTT-IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT 627
            S+P  TT +V + A T  TT + +  +VA+S    S P T       A+V +  +S    
Sbjct: 1164 SMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPT-------AEVTSMPTSTPGE 1216

Query: 628  STRPIITVHKSGTVTVAQQAQVVTT----VVGGVTKTITLVKSPISVPGGSALISNLGKV 683
             + P+ ++    T   + +A  ++T        VT +     SP +  G S   S   + 
Sbjct: 1217 RSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEG 1276

Query: 684  MSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL-----------PA-GTILKLVTSADGK 731
             +++ + PV T+ VT   ++  +T  + TKGP+           PA GT +   T ++G+
Sbjct: 1277 STLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGR 1336

Query: 732  P--------TTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGA 783
                     TT++ ++  S   T P +   + V+ ST    + T  +   M       G 
Sbjct: 1337 TPLTSIPVNTTLVASSAISILSTTP-VDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGT 1395

Query: 784  TGVTSSPGIKSPI------TIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG 837
            T +TS P   +P+      T+  T V TS  G  +   T+ P  A G         +   
Sbjct: 1396 TPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGIS-------IPTS 1448

Query: 838  APGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGA 897
             P +  T L+++P+      TPV  S      TT V   +  VT+       VS+S   A
Sbjct: 1449 TPSEGKTPLKSIPVSN----TPVANSEASTLSTTPVDSNSPVVTSTA-----VSSSPTPA 1499

Query: 898  GGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITM-QPVSQ 956
             G  TS +++TP  + G+ A L+S  ++ T +  S   +  T     +TP  T  Q  S 
Sbjct: 1500 EG--TSIAISTP--SEGSTA-LTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSS 1554

Query: 957  PTQV---TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVC 1013
            PT     ++ T+     + P+  LPVS +   ++E  T + T  DS +  V   T     
Sbjct: 1555 PTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDS-KTQVTAST----- 1608

Query: 1014 SNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVR 1073
                 E   + T   ++ T+     G P  T +          AS   ST+     S   
Sbjct: 1609 -----EASSSTTAEGSSMTISTPSEGSPLLTSIPV---STTPVASPEASTL-----STTP 1655

Query: 1074 VCSNPPCETH-ETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQ 1132
            V SN P  T  E  ++ T    TS     +     P  +    TT  A++A+S++     
Sbjct: 1656 VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLS---- 1711

Query: 1133 RDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPL 1192
                      T  V   +  T + EA     +   T   ++T +  T   T  P S  P+
Sbjct: 1712 ----------TTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPV 1761

Query: 1193 LGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKD---LPAGRHSHAVSTAAMTRSSVGA 1249
            L  S        +P        +S    SSP+  +   +P    S  ++    T  S   
Sbjct: 1762 L--SSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTL 1819

Query: 1250 GEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSN 1309
                 A    +    S S  VT TA+ +   P+   +   S P   +    +   +TT+ 
Sbjct: 1820 VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTV 1879

Query: 1310 AGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTM 1369
            A S     S  P  T    TT+   +++     G       P  GRP  T    ST T  
Sbjct: 1880 ASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVA 1939

Query: 1370 SVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGT 1429
            S  +  L      +   V +  + +++P  T   GT++  P P     S P      T  
Sbjct: 1940 SSEINTLSTTLADTRTPVTTYSQASSSP--TTADGTSM--PTPAYSEGSTP-----LTSM 1990

Query: 1430 THTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQ 1489
              + T V S+ +S     P  +      ST+G S   T+     T++ ++     TT   
Sbjct: 1991 PLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGG---TSIQTSTPSERTTPLA 2047

Query: 1490 STPVPGPSVPPPE--ELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV 1547
              PV    V   E   L  +P   +         S+S    G S  + + S+   L  ++
Sbjct: 2048 GMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSI 2107

Query: 1548 DLSSTGEPS--------SGQESAGSAVVATVVVQPPPPTQSEVDQ-----------LSLP 1588
             LS+T   S        +  +S    + +T V   P PT+    Q            S+P
Sbjct: 2108 PLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMP 2167

Query: 1589 QELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQ--------------ALA 1634
                  A +  +TL  T +      VT + EA +    +E                 ++ 
Sbjct: 2168 VSTTVVASSAISTLSTTPV-DTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMP 2226

Query: 1635 IQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEG--------QEGQA--TTIPI 1684
            +  +     +A   +  P+DTS    T T+A     +AEG         EG    T+IP+
Sbjct: 2227 VSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPV 2286

Query: 1685 VLTQQELAALVQQQQLQEAQAQQQHHHLP----TEALAP---ADSLNDPAIESNCLNELA 1737
              T      LV   ++          + P    TEA +P   A+  + P   S+  N   
Sbjct: 2287 SHT------LVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL 2340

Query: 1738 GTVPSTVALLPS--TATESLAPSNTFVAPQPVVVASPA-KLQAAATLTEVANGIESLGVK 1794
              +P +  ++ S  T+T S  P++T     PV   S A      A  T +     S G  
Sbjct: 2341 TRMPVSTTMVASFETSTLSTTPADT---STPVTTYSQAGSSPTTADDTSMPTSTYSEGST 2397

Query: 1795 PDLPPPPSKAPM 1806
            P    P S  P+
Sbjct: 2398 PLTSVPVSTMPV 2409



 Score =  177 bits (449), Expect = 9e-44
 Identities = 335/1492 (22%), Positives = 559/1492 (37%), Gaps = 219/1492 (14%)

Query: 401  DIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPT-TT 459
            D P  ++T  +PT +   S   +   +  P++      P T  G T +P + P+  + ++
Sbjct: 101  DTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEG-TDVPMSTPSEESISS 159

Query: 460  TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTG--TPLVTMRPASQAGKAPVTVT 517
            T+  + T P  S    T+   +   +    T  QA++   TP  T  P S   +    +T
Sbjct: 160  TMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLT 219

Query: 518  SLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAA--TQKIPPS---SAPTVLSVPA 572
            S+PA    V  +++   T++ +  ++S    ++A A++  T    PS   SAP+  S P 
Sbjct: 220  SMPASTMKVASSEAI--TLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPL 277

Query: 573  GTTIVKTM-AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP 631
                +  M  V+   +TL  T    + PV+ S  A+    TA    GTS+ ++T T    
Sbjct: 278  TRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAE---GTSIPTSTYTEGST 334

Query: 632  IITVHKSGTVTVAQQAQVVTTVVGGVTKT-ITLVKSPISVPGGSALISNLGKVMSVVQTK 690
             +T   + T+ VA       ++    T T +T    P S+P                 T 
Sbjct: 335  PLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLP-----------------TT 377

Query: 691  PVQTSAVTGQASTG--PVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT------TTQAS 742
               TS +T   S G  P+T        +P  TI  LV S++   T+ I        T AS
Sbjct: 378  AEATSMLTSTLSEGSTPLTN-------MPVSTI--LVASSEASTTSTIPVDSKTFVTTAS 428

Query: 743  GAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTK 802
             A + PT    +S++ ST   G+T +      +  +  + A+ ++++P      T +TT 
Sbjct: 429  EASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTP--VDSKTQVTTS 486

Query: 803  VMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAP--GQPGTILRTVPMGGVRLVTPV 860
               S +  P   + ++P      G   +T + +   P      + L T P   V   TPV
Sbjct: 487  TEAS-SSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTP---VDTSTPV 542

Query: 861  TV------SAVKPAVTTLVV----KGTTGVTTLGTVT--------GTVSTSLAGAGGHST 902
            T       S+  P  T++      +G+T +T +   T         T ST+ A +    T
Sbjct: 543  TTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVT 602

Query: 903  SASLATPITTL--GTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960
            ++S A+  +T   GT    S+     T IT  +  TTL A+   +T + T  PV   T V
Sbjct: 603  TSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTT--PVDSNTPV 660

Query: 961  TLIT-APSGVEAQPVHDLPVSIL---ASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNP 1016
            T  T A S         +P S     ++P T  P  T  +A S    +         S  
Sbjct: 661  TTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTL---------STT 711

Query: 1017 PCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQ--NGSVVRV 1074
            P +T    TT+T  ++      G   PT         E +  L +  V +     S    
Sbjct: 712  PVDTSTPVTTSTEASSSPTTADGASMPTSTP-----SEGSTPLTSMPVSKTLLTSSEAST 766

Query: 1075 CSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRD 1134
             S  P +T    TT+T          +  CS     T   GT+   +T            
Sbjct: 767  LSTTPLDTSTHITTST----------EASCS----PTTTEGTSMPISTP----------- 801

Query: 1135 ARRACAAGTPAVIRISVATGAL---EAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGP 1191
                 + G+P +  I V+   +   EA+  S +   +     TST ++   T A  ++ P
Sbjct: 802  -----SEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMP 856

Query: 1192 LLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGE 1251
                S  R P    P    L   S+   LS+  +        S  V+ +   RSS    E
Sbjct: 857  TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDT------STPVTNSTEARSSPTTSE 910

Query: 1252 PRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAG 1311
                P     +G +P T++  +    +   + T+    S  P +T    TT+T  TS+  
Sbjct: 911  GTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTL----SATPVDTSTPVTTSTEATSSPT 966

Query: 1312 SAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTST--GTTM 1369
            +A+   ++ P  T   GTT   +T  S+      E            T  TTST   +  
Sbjct: 967  TAEG--TSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP 1024

Query: 1370 SVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGT 1429
              + G  +P +T S           + P       T ++A   T  + S  P +T    T
Sbjct: 1025 PTAEGTSMPTSTPSE---------GSTPLTRMPVSTTMVASSETSTL-STTPADTSTPVT 1074

Query: 1430 THTATTVTSNMSSNQDPPPAASDQGEVESTQGD-----SVNITSSSAITTTVSSTLTRAV 1484
            T++  + +S  +     P +   +G    T         V+  +S+  TT V +++    
Sbjct: 1075 TYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTT 1134

Query: 1485 TTVTQSTP--VPGPSVP--PPEELQVSPGPRQQLPPRQLL------QSASTALMGESAEV 1534
            +T   S+P    G S+P  PP E      P   +P    L       + ST  +    +V
Sbjct: 1135 STEASSSPTTAEGTSIPTSPPSE---GTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQV 1191

Query: 1535 LSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAE 1594
             ++++    P   +++S    + G+    S  + ++ V+  P   SE   LS       +
Sbjct: 1192 ATSTEASSPPPTAEVTSMPTSTPGER---STPLTSMPVRHTPVASSEASTLSTSP---VD 1245

Query: 1595 AQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQAL----AIQAVLQAAQQAVMGTG 1650
                 TT   T  +P     T A   +   + T E   L     +   L  + +A     
Sbjct: 1246 TSTPVTTSAETSSSP-----TTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLT 1300

Query: 1651 EPMDTSEAAATVTQAELGHLSAEG--------QEGQA--TTIPIVLTQQELAALVQQQQL 1700
             P+DT     T  +       AEG         EG+   T+IP+  T      LV    +
Sbjct: 1301 TPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTT------LVASSAI 1354

Query: 1701 QEAQAQQQHHHLP----TEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLA 1756
                     +  P    TEA +   +    ++ ++  N   GT P T   +P + T  ++
Sbjct: 1355 SILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNS--NPSEGTTPLT--SIPVSTTPVVS 1410

Query: 1757 PSNTFVAPQPVVVASPAKLQAAATLT-EVANGIESLGVKPDLPPPPSKAPMK 1807
               + ++  PV  ++P    A AT +   A GI      P   P   K P+K
Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTAEGISI----PTSTPSEGKTPLK 1458



 Score =  175 bits (444), Expect = 4e-43
 Identities = 312/1471 (21%), Positives = 570/1471 (38%), Gaps = 161/1471 (10%)

Query: 373  VRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAA 432
            V  +  S+ VS   VA++++  L     D      T+T  + +P  +  ++ P S     
Sbjct: 2631 VSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER 2690

Query: 433  AAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP 492
            + P    L  V  TLL  +  +  +TT +        +S  V T+A     P   + T  
Sbjct: 2691 STPLTNIL--VSTTLLANSEASTLSTTPVD-------TSTPVTTSAEASSSPTTAEGTSM 2741

Query: 493  QATT----GTPL----VTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMS 544
            + +T     TPL    V+  P + +  + V+ T++   + +   T+++      SSP  +
Sbjct: 2742 RISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEAS------SSPTTA 2795

Query: 545  GMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATV--KVASSP--- 599
             + ++  +  +    P +S P V   P  ++   T++ TP  T+ P T   K +SSP   
Sbjct: 2796 EVTSMPTSTPSETSTPLTSMP-VNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854

Query: 600  ----VMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVG 655
                V +S  +       +  V T+  +++  ST     V  S  VT + +     T   
Sbjct: 2855 EGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE 2914

Query: 656  GVTKTITLVKSPISVPGGSALISNL---GKVMSVVQTKPVQT------------SAVTGQ 700
            G +  I+   S +S P  S L+S +   G   S + T PV T            S  T +
Sbjct: 2915 GTSMPIS-TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAE 2973

Query: 701  ASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPST 760
             ++ P++   + + PL + ++  +  ++    T   T    S     P      + S  T
Sbjct: 2974 GTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTS----TPVTTSTEASSSPT 3029

Query: 761  TKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVM-TSGTGAPAKIITAVP 819
            T  GT   I T          G+T +TS P   +P+ I     + T+   + + ++T+  
Sbjct: 3030 TAEGTGIPIST-------PSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTE 3082

Query: 820  KIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTG 879
              ++    +G +  +   + G   T L  VP+      TPVT SA+    TT  V  +T 
Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGS--TPLTGVPVS----TTPVTSSAISTLSTT-PVDTSTP 3135

Query: 880  VTTLGTVTGTVSTSLAGAGGHSTSASLATPITTL--GTIATLSSQ--VINPTAITVSAAQ 935
            VTT      + +TS   +   ST +  +TP+T +   T+  +SS+   ++ T +  S   
Sbjct: 3136 VTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195

Query: 936  TTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVT 995
            TT T A   TT   T  P S P++         V   PV     SIL++   +  T   T
Sbjct: 3196 TTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTT 3255

Query: 996  IADSGQGDVQPGTV--TLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQ 1053
               S +    P T   T + ++ P E     T+   +TT VA+       ++   +    
Sbjct: 3256 ---STEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVAS-------SETSTLSTTP 3305

Query: 1054 EAAASLVTSTVGQQNGSVVRVCSNPPCETHETGT---TNTATTATSNMAGQHG-CSNPPC 1109
               ++ VT+     +   +   ++ P  T+  G+   TN + + T  ++ +    S  P 
Sbjct: 3306 ADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPV 3365

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTR 1169
            +T    TT+T   ++S   A        + + GT  +  + V+T  + +++ +       
Sbjct: 3366 DTSTPVTTST-EASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPV 3424

Query: 1170 QTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLS-SKVRLSSPSIKDL 1228
             ++   TT T  ++    + G  L  S   E  G +P  + + PLS + V  S  S    
Sbjct: 3425 DSNTLVTTSTEASSSPTIAEGTSLPTSTTSE--GSTP--LSIMPLSTTPVASSEASTLST 3480

Query: 1229 PAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQV 1288
                 S  V+T++ T SS    E    P   + +G +P T + V+        ++T+   
Sbjct: 3481 TPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTL--- 3537

Query: 1289 CSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGG 1348
             S  P +++   T+++  +S+  + Q         +  + +  T   +++   + +    
Sbjct: 3538 -STTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTP 3596

Query: 1349 QQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVT-PQAGTAL 1407
              P   R      +T + +T +      LP +T S  +    +   +  SVT  +AGTA 
Sbjct: 3597 STPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTAS 3656

Query: 1408 LAPFPTQ-------RVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQ 1460
              P  T        +V S+P       GTT    T +   +     P + +     E + 
Sbjct: 3657 TLPVDTSTPVITSTQVSSSP---VTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGST 3713

Query: 1461 GDSVNITSSSAITTT---VSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPR 1517
              + ++ +S+ +TT+   +SS+ T   TT++ S P+   ++     +  +P  R      
Sbjct: 3714 LSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESST 3773

Query: 1518 QLLQSASTAL-MGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQP-P 1575
              + S  T++ M  ++E  S+  T E    + +S+T E S+        ++ TV++ P  
Sbjct: 3774 PSIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERST--------LLTTVLISPIS 3825

Query: 1576 PPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAI 1635
              + SE   LS P          T+T ++T       ++ A       +  +E +  L  
Sbjct: 3826 VMSPSEASTLSTP-------PGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTT 3878

Query: 1636 QAVLQAAQQAVMGTG----EPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQEL 1691
              V      +  G       P+DTS      T                 TIP+  T    
Sbjct: 3879 LLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDT-----------ASTPTIPVATT---- 3923

Query: 1692 AALVQQQQLQEAQAQQQHHHLPTEAL---------APADSLNDPAIESNCLNELAGTVPS 1742
               +    + E         +P+  +         A   +++ P I S  LN  + +  S
Sbjct: 3924 ---ISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSS 3980

Query: 1743 TVALLPSTATESLAPSNTFVAPQPVVVASPA 1773
            T     ST  E   P+ T  AP   V  S A
Sbjct: 3981 TTTSF-STTKEFTTPAMTTAAPLTYVTMSTA 4010



 Score =  175 bits (443), Expect = 5e-43
 Identities = 332/1490 (22%), Positives = 554/1490 (37%), Gaps = 225/1490 (15%)

Query: 360  ETEKPPPP--ARVQLVRANTNSLEVSWGAVATA-----DSYLLQLQKYDI--PATAATAT 410
            +T  P  P    V +   +  S+  +   V+TA     ++Y     K D+  P T +T  
Sbjct: 135  DTSSPTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQA 194

Query: 411  SPTPN-----------------PVPSVPANPPKSPAPAAAAPAVQPLT-QVGITLLPQAA 452
            S +P                  P+ S+PA+  K  +  A      P+     +T+  QA+
Sbjct: 195  SSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQAS 254

Query: 453  PAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATT--GTPLVTMRP---AS 507
             +P T       P++  S+ S  +   T+   +V+ V   +A+T   TP  T  P   ++
Sbjct: 255  SSPTTAEG----PSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITST 310

Query: 508  QAGKAPVTV--TSLPA-----GVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIP 560
            +A  +P T   TS+P      G   +  T ++   V  S      +  +  +   T    
Sbjct: 311  EASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTE 370

Query: 561  PSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPA---TRMLKTAAAQV 617
            PSS PT     +  T   +   TP T    +T+ VASS    ++     ++   T A++ 
Sbjct: 371  PSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEA 430

Query: 618  GTSVSSATNTS---------TRPIITVHKSGT-VTVAQQAQVVTTVVGGVTKTITLVKSP 667
             +S ++A +TS         + P+ ++  S T V  ++ + + TT V   T+  T  ++ 
Sbjct: 431  SSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEAS 490

Query: 668  ISVP--------------GGSALISNLGKVMSVVQTK-------------PVQTSAVTGQ 700
             S P              G + L S     M V  ++             PV TS+    
Sbjct: 491  SSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS 550

Query: 701  ASTGPVTQIIQTKGPLPAGTIL-------KLVTSADGKPTT-------IITTTQASGAGT 746
            +ST P    I T  P    T L       +LV S++   T+          TT +  + +
Sbjct: 551  SSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSS 610

Query: 747  KPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTS 806
              T  G S  + + ++ GTT    ++  + + +   +T  T+     +P+T  +T+  +S
Sbjct: 611  STTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVT-TSTEATSS 669

Query: 807  GTGAPAKIITAVPKIATGHGQQGVTQVVLKG--APGQPGTILRTVPMGGVRLVTPVTVSA 864
             T A     T++P      G   +T + +          + L T P+     VT  T ++
Sbjct: 670  STTAEG---TSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEAS 726

Query: 865  VKPAV-------TTLVVKGTTGVTTL--------GTVTGTVSTSLAGAGGHSTSASLA-- 907
              P         T+   +G+T +T++         +   T+ST+      H T+++ A  
Sbjct: 727  SSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASC 786

Query: 908  TPITTLGT---IATLSSQVINPTAITVSAAQTTLTAAGGL-TTPTITMQPVSQPTQVTLI 963
            +P TT GT   I+T S      T+I VS    T   A  L TTP  +  PV+  T+V+  
Sbjct: 787  SPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVS-- 844

Query: 964  TAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHET 1023
            ++P+  E   +     S   +P T  P +T  +A S    +         S  P +T   
Sbjct: 845  SSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTL---------STTPVDTSTP 895

Query: 1024 GTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETH 1083
             T +T   +      G   PT      +      S+  ST    + S  R  S  P +T 
Sbjct: 896  VTNSTEARSSPTTSEGTSMPTSTP--GEGSTPLTSMPDSTTPVVS-SEARTLSATPVDTS 952

Query: 1084 ETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGT 1143
               T  T+T ATS+     G S P      T T +  TT ++S   +H   A    +   
Sbjct: 953  TPVT--TSTEATSSPTTAEGTSIP------TSTPSEGTTPLTSTPVSHTLVANSEAS--- 1001

Query: 1144 PAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGG 1203
                        L       +   T  T A+S   T   T  P S      PS    P  
Sbjct: 1002 -----------TLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTST-----PSEGSTPLT 1045

Query: 1204 RSPAFVQLAPLSSKVRLS-SPSIKDLPAGRHSHAVSTA------AMTRSSVGAGEPRM-- 1254
            R P    +   S    LS +P+    P   +S A S++      +M  S+   G   +  
Sbjct: 1046 RMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTS 1105

Query: 1255 APVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNP--------PCETHETGTTNTA- 1305
             PV   L   S ++T++ T ++  + P  T T+  S+P        P      GTT  A 
Sbjct: 1106 VPVSTRLVVSSEASTLSTTPVDTSI-PVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLAS 1164

Query: 1306 ----TTSNAGSAQRVCSNPPCETHETGTTHT------ATTATSNGGTGQPEGGQQPPAGR 1355
                TT    S     S  P ++     T T       T   ++  T  P     P    
Sbjct: 1165 MPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSM 1224

Query: 1356 PC-ETHQTTSTGTTMSVSVGALLPDATSSHRTVES--GLEVAAAPSVTPQAGTALLAPFP 1412
            P   T   +S  +T+S S        T+S  T  S    E  + P+ T   G+ LL   P
Sbjct: 1225 PVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP 1284

Query: 1413 -TQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSA 1471
             +  + ++P   T  T    T   V ++   +  P PA        +       +TS   
Sbjct: 1285 VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPV 1344

Query: 1472 ITTTVSSTLTRAVTT--VTQSTPV----PGPSVPPPEELQVSP--GPRQQLPPRQLLQSA 1523
             TT V+S+    ++T  V  STPV       S P   E    P   P +   P   +  +
Sbjct: 1345 NTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS 1404

Query: 1524 STALMGESAEVLSASQT-PELPAAVDLSSTGEPSSGQ--------ESAGSAVVATVVVQP 1574
            +T ++   A  LSA+      P      +T  P++ +         S G   + ++ V  
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN 1464

Query: 1575 PPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEE---LAVTAAAEAAAQAAATEEAQ 1631
             P   SE   LS    + + +   T+T + +  TP E   +A++  +E +          
Sbjct: 1465 TPVANSEASTLS-TTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALT------ 1517

Query: 1632 ALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATT 1681
            ++ +     A+ +    +  P  TS    T +QA     +A+G   Q +T
Sbjct: 1518 SIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTST 1567



 Score =  174 bits (442), Expect = 6e-43
 Identities = 315/1466 (21%), Positives = 548/1466 (37%), Gaps = 175/1466 (11%)

Query: 379  SLEVSWGAVATADSYLLQLQKYD--IPATAAT--ATSPTPNPVPSVPANPPKSPAPAAAA 434
            S+ VS   VA++++  +     D  IP T +T  ++SPT   V S+P + P   +     
Sbjct: 2755 SILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETST---- 2810

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSI----SVPTAARTQGVPAVLKVT 490
                PLT + +   P A+    T +T  V  + P ++     S PT A    VP      
Sbjct: 2811 ----PLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASE 2866

Query: 491  GPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQ------SAQGTVIGSSPQMS 544
            G    T  P+ T  P + +  + ++ T +   + +   T+      +A+GT +  S    
Sbjct: 2867 GSTLLTSIPVSTT-PVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSE 2925

Query: 545  GMAALAAAAAATQKIPPSSAPTVLSVPAGT-TIVKTMA-VTPGTTTLPATVKVASSPVMV 602
                L +   +T  +  S A T+ + P  T T V T A  +   TT   T    S+P   
Sbjct: 2926 VSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGER 2985

Query: 603  SNPATRM----LKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQV-VTTVVGGV 657
              P T M    +  A+++  T   +  +TST    +   S + T A+   + ++T   G 
Sbjct: 2986 RTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045

Query: 658  TK--TITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG----------- 704
            T   +I +  +P+++P  S L +      S V T    +S+ T    T            
Sbjct: 3046 TPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGST 3105

Query: 705  PVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPG 764
            P+T +  +  P+ +  I  L T+     T + T+T+A  +   PT    +S+  ST   G
Sbjct: 3106 PLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSS---PTTSEGTSMPTSTPSEG 3162

Query: 765  TTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATG 824
            +T +   +P+S ++  +      S+  + +   + T+   TS T A     T++P     
Sbjct: 3163 STPLTY-MPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEG---TSIPTSTPS 3218

Query: 825  HGQQGVTQVVLKGAP--GQPGTILRTVPMGGVRLVTPVTVSAVKPAV-------TTLVVK 875
             G   +T V +   P      +IL T P+     +T  T ++  P         T+   +
Sbjct: 3219 EGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSE 3278

Query: 876  GTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAI---TVS 932
            G+T +T++   T TV++S       +T A  +TP+TT    A+ S  + + T++   T S
Sbjct: 3279 GSTPLTSMPVSTTTVASSETSTLS-TTPADTSTPVTTYSQ-ASSSPPIADGTSMPTSTYS 3336

Query: 933  AAQTTLTAAGGLTTP-------TITMQPVSQPTQVTLIT----APSGVEAQPVHDLPVSI 981
               T LT     TTP       T++  PV   T VT  T    +P+  E   +     S 
Sbjct: 3337 EGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSE 3396

Query: 982  LASPTTEQPTATVTIADSGQGDVQPGTV---TLVCSNPPCETHETGTTNTATTTVVANLG 1038
              +P    P +T  +  S    +    V   TLV ++    +  T    T+  T   + G
Sbjct: 3397 GTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEG 3456

Query: 1039 GHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNM 1098
              P             + AS +++T    +  V    S+P   T+ + TT   T+  ++ 
Sbjct: 3457 STPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTT--SSP---TNSSPTTAEVTSMPTST 3511

Query: 1099 AGQHGC--SNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGAL 1156
            AG+     +N P  T    ++  +T + + V +N    +    A+ +PA ++++  T  +
Sbjct: 3512 AGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQ-ASSSPATLQVT--TMRM 3568

Query: 1157 EAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGR-SPAFVQLAPLS 1215
                   S   T   S+T  T +  +T +  S       + + +     +P  V   P+S
Sbjct: 3569 STPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMS 3628

Query: 1216 SKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEP----RMAPVCESLQGGSPSTTVT 1271
            +   +S+P +  +P       VST ++T S  G           PV  S Q  S   T  
Sbjct: 3629 TPSEVSTP-LTIMP-------VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPE 3680

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T +  +  PS   T + + P   T  T +  +       S   V ++ P  T     + 
Sbjct: 3681 GTTMP-IWTPSEGSTPLTTMPVSTTRVTSSEGSTL-----STPSVVTSTPVTTSTEAISS 3734

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            +AT  ++      P               + ++ GTT+ VS   +     SS  ++ S  
Sbjct: 3735 SATLDSTTMSVSMPM--------------EISTLGTTILVSTTPVTRFPESSTPSIPS-- 3778

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTS------NMSSNQD 1445
             V  + S+T  A     +P   +   + P   T E  T  T   ++       + +S   
Sbjct: 3779 -VYTSMSMTT-ASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLS 3836

Query: 1446 PPPAASDQGEVESTQGDSVNI-----TSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
             PP  +    + ST+  S +I     T   +IT+  S+ LT  + + T  T  PG S+  
Sbjct: 3837 TPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIAS 3896

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQE 1560
               L  S              S  TA             TP +P A  +S +        
Sbjct: 3897 TPPLDTST---------TFTPSTDTA------------STPTIPVATTISVS------VI 3929

Query: 1561 SAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA 1620
            + GS    T+ +   P T S  D        +  A  G  +  V   T      T+++  
Sbjct: 3930 TEGSTPGTTIFIPSTPVTSSTAD--------VFPATTGAVSTPVITSTELNTPSTSSSST 3981

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
                + T+E    A+          +        T+    T + + L   S        T
Sbjct: 3982 TTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVT 4041

Query: 1681 TIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTV 1740
            T P+  + +                   H   P    A + ++N  A+ +        T 
Sbjct: 4042 TRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTR----TK 4097

Query: 1741 PSTVALLPSTATESLAPSNTFVAPQP 1766
            PST      T T +  P+NT +   P
Sbjct: 4098 PSTRTTSFPTVTTTAVPTNTTIKSNP 4123



 Score =  164 bits (415), Expect = 8e-40
 Identities = 296/1237 (23%), Positives = 468/1237 (37%), Gaps = 203/1237 (16%)

Query: 374  RANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAA 433
            R    S+ VS   VA++++  L     D      T+T  + +P  +     P S     +
Sbjct: 2986 RTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGS 3045

Query: 434  APAVQPLTQVGITLLPQAAPAPPTTTTIQV---LPTVPGSSISV-PTAARTQGVPAVLKV 489
             P    LT + ++  P A P   T +T  V    P V  + +S  PT A    +P     
Sbjct: 3046 TP----LTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYS 3101

Query: 490  TGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAAL 549
             G    TG P+ T    S A     T+++ P      V T     T   SSP  S   ++
Sbjct: 3102 EGSTPLTGVPVSTTPVTSSAIS---TLSTTPVDTSTPVTTS----TEAHSSPTTSEGTSM 3154

Query: 550  AAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGT-TTLPATVKVASSPVMVSNPATR 608
                       P+S P+  S P     V TM V     +TL AT    S+PV  S  AT 
Sbjct: 3155 -----------PTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATS 3203

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVV-TTVVGGVTKTITLVKS- 666
                    + TS  S   T   P+ +V  S T   + +A ++ TT V   T   T  ++ 
Sbjct: 3204 STTAEGTSIPTSTPSEGMT---PLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEAS 3260

Query: 667  -----------PISVPG-GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKG 714
                       P S P  GS  ++++    + V +    T + T   ++ PVT   Q   
Sbjct: 3261 SSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASS 3320

Query: 715  --PLPAGTILKLVTSADGKP--------TTIITTTQASGAGTKP-------TILGISSVS 757
              P+  GT +   T ++G          TT + +++AS   T P       T    +S+S
Sbjct: 3321 SPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLS 3380

Query: 758  PSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTK-------VMTSGTGA 810
            P TT  GT+  I T   S   T   +  V+++P + S +  ++T        V TS   +
Sbjct: 3381 P-TTAEGTS--IPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEAS 3437

Query: 811  PAKII---TAVPKIATGHGQQGVTQVVLKGAP--GQPGTILRTVPMGGVRLVTPVTVSA- 864
             +  I   T++P   T  G   ++ + L   P      + L T P   V   TPVT S+ 
Sbjct: 3438 SSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTP---VDTSTPVTTSSP 3494

Query: 865  ---------VKPAVTTLVVKGTTGVTTLGTVT--------GTVSTSLAGAGGHSTSASLA 907
                     V    T+   +G+T +T +   T         T+ST+   +    TS+S A
Sbjct: 3495 TNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQA 3554

Query: 908  TP------ITTLGTI------ATLSSQVINPTAITVSAAQTTLTAAGGLTTP-TITMQPV 954
            +       +TT+         ++L++ +++ T +T S A T  T +   +TP T + Q  
Sbjct: 3555 SSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSN 3614

Query: 955  SQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTAT--VTIADSGQGDVQP-GTVTL 1011
            S PT   +IT P    ++         +++P T  P +T  VTI+++G     P  T T 
Sbjct: 3615 STPTPPEVITLPMSTPSE---------VSTPLTIMPVSTTSVTISEAGTASTLPVDTSTP 3665

Query: 1012 VCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSV 1071
            V ++    +       T       + G  P  T           + + VTS+ G    S 
Sbjct: 3666 VITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTM--------PVSTTRVTSSEGSTL-ST 3716

Query: 1072 VRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANH 1131
              V ++ P  T     +++AT  ++ M+      + P E    GTT   +T         
Sbjct: 3717 PSVVTSTPVTTSTEAISSSATLDSTTMS-----VSMPMEISTLGTTILVSTT-------- 3763

Query: 1132 QRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGP 1191
                 R   + TP++  +  +     A++GS S      T+   TT   M+T +  S   
Sbjct: 3764 --PVTRFPESSTPSIPSVYTSMSMTTASEGSSSP-----TTLEGTTTMPMSTTSERST-- 3814

Query: 1192 LLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGE 1251
            LL               V ++P+S  +  S  S    P G  S  + T+    S     E
Sbjct: 3815 LL-------------TTVLISPISV-MSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAE 3860

Query: 1252 PRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGT--TNTATTSN 1309
                 +  + +  +P TT+ V+       P A++    S PP +T  T T  T+TA+T  
Sbjct: 3861 VTTIRISITSERSTPLTTLLVSTTLPTSFPGASIA---STPPLDTSTTFTPSTDTASTPT 3917

Query: 1310 AGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTM 1369
               A  +  +   E    GTT    +      T             P  T    +T +T 
Sbjct: 3918 IPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELNTPSTS 3977

Query: 1370 SVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGT 1429
            S S       + S+ +   +     AAP       TA   P  T R C+        T T
Sbjct: 3978 SSSTTT----SFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATST 4033

Query: 1430 THTATTVT-------------SNMSSNQDP---PPAASDQGEVESTQGDSVNITSSSAIT 1473
             HT+T+VT             S ++S+  P   PPA S      S    +VN  + + +T
Sbjct: 4034 PHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMT 4093

Query: 1474 T-TVSSTLTRAVTTVT----------QSTPVPGPSVP 1499
            T T  ST T +  TVT          +S P   P+VP
Sbjct: 4094 TRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVP 4130



 Score = 85.5 bits (210), Expect = 5e-16
 Identities = 185/862 (21%), Positives = 304/862 (35%), Gaps = 140/862 (16%)

Query: 978  PVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANL 1037
            P   L+  T  + T+  +   S    V    +T   S    E+    TT   ++T   + 
Sbjct: 79   PRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSS 138

Query: 1038 GGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGT--TNTATTAT 1095
               P+ T V      +E+ +S +         + V     P  E + + T   + +T  T
Sbjct: 139  PTTPEGTDVPMSTPSEESISSTM---------AFVSTAPLPSFEAYTSLTYKVDMSTPLT 189

Query: 1096 SNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGA 1155
            ++       + P   T    T +  +T ++S+ A+  + A           + IS     
Sbjct: 190  TSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEIS----- 244

Query: 1156 LEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSA-GPLLG---PSMAREPGGRSPAFVQL 1211
                              T  T++  A+ +P +A GP L    PS    P  R P  V L
Sbjct: 245  ------------------TPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVML 286

Query: 1212 APLSSKVRLSS-PSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTV 1270
               S    LS+ P+  ++P       V T+    SS    E    P     +G +P T+ 
Sbjct: 287  VVSSEASTLSTTPAATNIP-------VITSTEASSSPTTAEGTSIPTSTYTEGSTPLTST 339

Query: 1271 TVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTT 1330
              + +       +T+    S  P +T    TT+T  +S   +A+               T
Sbjct: 340  PASTMPVATSEMSTL----SITPVDTSTLVTTSTEPSSLPTTAE--------------AT 381

Query: 1331 HTATTATSNGGTGQPEGGQQPPAGRPCET-------HQTTSTGTTMSVSVGALLPDATSS 1383
               T+  S G T        P    P  T         TTST    S +      +A+SS
Sbjct: 382  SMLTSTLSEGST--------PLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSS 433

Query: 1384 HRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTA-----TTVTS 1438
              T E      +  + TP  G+  L   P     S  P  + E     T      T VT+
Sbjct: 434  PTTAED----TSIATSTPSEGSTPLTSMPV----STTPVASSEASNLSTTPVDSKTQVTT 485

Query: 1439 NMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST--LTRAVTTVTQSTPVPGP 1496
            +  ++  PP A  +     +    S  +TS S  T  V+S+   T + T V  STPV   
Sbjct: 486  STEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTS 545

Query: 1497 SVPPPEELQVSPGPRQQLPPRQLLQSASTAL--MGESAEVLSASQTPELPAAVDLSSTGE 1554
            S    E    S  P     P       ST L  M  S  ++ +S+          S+T  
Sbjct: 546  S----EASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFV 601

Query: 1555 PSSGQESAGSAVVATVVVQPPPPTQSE----VDQLSLPQELMAEAQAGT-TTLMVTGLTP 1609
             +S + S+ S       +  P  T SE    +  +S+   L+A ++A T +T  V   TP
Sbjct: 602  TTSSEASSSSTTAEGTSM--PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTP 659

Query: 1610 EELAVTAAAEAAAQAAATEEAQ--------------ALAIQAVLQAAQQAVMGTGEPMDT 1655
                VT + EA + +   E                 ++ +   L A+ +A   +  P+DT
Sbjct: 660  ----VTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDT 715

Query: 1656 SEAAATVTQAELGHLSAEG--------QEGQA--TTIPI---VLTQQELAAL--VQQQQL 1700
            S    T T+A     +A+G         EG    T++P+   +LT  E + L        
Sbjct: 716  STPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTS 775

Query: 1701 QEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNT 1760
                   +    PT     +  ++ P+  S  L  +  ++    +   ST + +   SN+
Sbjct: 776  THITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNS 835

Query: 1761 FVAPQPVVVASPAKLQAAATLT 1782
             V     V +SP   +  +  T
Sbjct: 836  PVTTSTEVSSSPTPAEGTSMPT 857



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 109/489 (22%), Positives = 180/489 (36%), Gaps = 57/489 (11%)

Query: 332  TRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRANTNSLEVSWGAV--AT 389
            T + IW+  +G        V    +   E      P+ V      T++  +S  A   +T
Sbjct: 3682 TTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDST 3741

Query: 390  ADSYLLQLQKYDIPATAATATSPTP----NPVPSVPANPPKSPAPAAAAPAVQPLTQVGI 445
              S  + ++   +  T   +T+P      +  PS+P+         A+  +  P T  G 
Sbjct: 3742 TMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGT 3801

Query: 446  TLLPQAAPAPPTT--TTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTM 503
            T +P +  +  +T  TT+ + P     S+  P+ A T        ++ P   T TPL+T 
Sbjct: 3802 TTMPMSTTSERSTLLTTVLISPI----SVMSPSEAST--------LSTPPGDTSTPLLTS 3849

Query: 504  RPASQAGKAPVTVTSLPAGV---RMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIP 560
              A      P  VT++   +   R    T     T + +S   + +A+      +T   P
Sbjct: 3850 TKAGSFS-IPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTP 3908

Query: 561  PSSAPTVLSVPAGTTI---VKTMAVTPGTT--------------TLPATVKVASSPVMVS 603
             +   +  ++P  TTI   V T   TPGTT                PAT    S+PV+ S
Sbjct: 3909 STDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITS 3968

Query: 604  NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITL 663
                    T+++   TS S+    +T  + T      VT++       T   G T + + 
Sbjct: 3969 TELNTP-STSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSAST 4027

Query: 664  VKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL----PAG 719
            + S  S P  S  ++          T+PV  S+ + + ST     I  T  P     P  
Sbjct: 4028 L-SATSTPHTSTSVT----------TRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPT 4076

Query: 720  TILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            T     T      TT+ T T+ S   T    +  ++V  +TT     T   T+P +    
Sbjct: 4077 TSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCF 4136

Query: 780  QAGATGVTS 788
              G     S
Sbjct: 4137 GDGCQNTAS 4145


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score =  164 bits (416), Expect = 6e-40
 Identities = 313/1330 (23%), Positives = 463/1330 (34%), Gaps = 188/1330 (14%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            + T ++ V  G+ ATA S          P  + TAT+PT   V S  A P  SP  A A 
Sbjct: 3729 STTATVTVPTGSTATASSTQATA---GTPHVSTTATTPT---VTSSKATPFSSPGTATAL 3782

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
            PA++            A P+    TT   L     S  + PTA  +   P+    T   A
Sbjct: 3783 PALRSTATTPTATSFTAIPSSSLGTTWTRL-----SQTTTPTATMSTATPS---STPETA 3834

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMV-VPTQSAQGTVI--GSSPQMSGMAALAA 551
             T T L T    ++A  +  T +S P       VPT +  G  +   SSP   G A    
Sbjct: 3835 HTSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSP---GTARTPP 3891

Query: 552  AAAATQKIPPSSAPTVL--SVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRM 609
               +T   P +S  TV   SVP GTT   T+  T  TT    ++   SS    S     +
Sbjct: 3892 VWISTTTTPTTSGSTVTPSSVP-GTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSL 3950

Query: 610  LKTAAAQVGTSVSSATNTSTRPIIT-----VHKSGTVTVAQQAQVVTTVVGGVTKTITLV 664
            + TA     T+  S TN S+ P  T     +  + T   A  + V  +   G T T  + 
Sbjct: 3951 ITTATTI--TATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVP 4008

Query: 665  KSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKL 724
             +  +  G S   S+   V      +   TSA +G   T  +T+        PA T    
Sbjct: 4009 NTTATTHGRSLSPSSPHTV------RTAWTSATSGTLGTTHITEPSTGTSHTPAAT---- 4058

Query: 725  VTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGAT 784
             T      T  +++   S   T+      S  SP TT PG TT       +A  ++   +
Sbjct: 4059 -TGTTQHSTPALSSPHPSSRTTE------SPPSPGTTTPGHTTATSRTTATATPSKTRTS 4111

Query: 785  GVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG------- 837
             +  S    +PIT + T            +  + P      G       +          
Sbjct: 4112 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ 4171

Query: 838  -------APGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTV 890
                   A  QPG     VP+G +  V   ++         LV +    V          
Sbjct: 4172 PLGLECRAQAQPG-----VPLGELGQVVECSLD------FGLVCRNREQVGKFKMCFNYE 4220

Query: 891  STSLAGAGGHSTS----ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT 946
                    GH  S    +S A P +T GT   L       T +T +A  TT  + G   T
Sbjct: 4221 IRVFCCNYGHCPSTPATSSTAMPSSTPGTTWIL-------TELTTTA--TTTASTGSTAT 4271

Query: 947  PTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQP 1006
            P+ T      P    ++T+P+          P +  +  T+     T T           
Sbjct: 4272 PSSTPGTAPPP---KVLTSPA--------TTPTATSSKATSSSSPRTATTLPVLTSTATK 4320

Query: 1007 GTVTLVCSNPPCETHETGTTNTATTTVVANLGG-HPQPTQVQFVCDRQEAAASLVTSTVG 1065
             T T V   P      TGT    TTT VA +   HP  T             +  TSTV 
Sbjct: 4321 STATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSST-----------PETTHTSTVL 4369

Query: 1066 QQNGSVVRVCSNPPCETHETGTT--NTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                +  R  S+    +   GTT   T  T  +      G +  P  T  T    T  T 
Sbjct: 4370 TTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTT 4429

Query: 1124 MSSVGANHQRDARRACAAGTPAVI-------RISVATGALEAAQGSKSQCQTRQTSATST 1176
             ++  A+    A  +   GT  ++        ++V TG+   A  +++   T   S T+T
Sbjct: 4430 TATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTAT 4489

Query: 1177 TMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHA 1236
            T TV ++ A  S+ P    ++   P  RS A             ++P+           A
Sbjct: 4490 TPTVTSSKATPSSSPGTATAL---PALRSTA-------------TTPT-----------A 4522

Query: 1237 VSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCET 1296
             S  A+  SS+G    R+            S T T TA  +   PS+T       P    
Sbjct: 4523 TSFTAIPSSSLGTTWTRL------------SQTTTPTATMSTATPSST-------PETVH 4563

Query: 1297 HETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRP 1356
              T  T TATT+ A  +    S+ P   H T    T TT  +   +  P     PP    
Sbjct: 4564 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS 4623

Query: 1357 CETHQTTSTGTTMSVSV-GALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQR 1415
              T  TT+T TT   +V  + +P  T + R + +        + T  A  ++  P  + +
Sbjct: 4624 TTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTT--------TTTTVATGSMATPSSSTQ 4675

Query: 1416 VCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVEST-QGDSVNITSSSAITT 1474
                PP  T  T TT TAT  T+N SS     P         +T    S   TSSS+  T
Sbjct: 4676 TSGTPPSLT-TTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRT 4734

Query: 1475 TVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534
              ++TL    +T T+ST      +P          P Q   P   + +  T+   E+   
Sbjct: 4735 --ATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHT 4792

Query: 1535 LSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE--LM 1592
             S   T         +ST  PSS   +       T        T S     S P    ++
Sbjct: 4793 -STVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSSTPGTTWIL 4851

Query: 1593 AEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEP 1652
             E     T ++ TG T         A A++        + +   A +  A  + + +   
Sbjct: 4852 TEPSTIATVMVPTGST---------ATASSTLGTAHTPKVVTTMATMPTATASTVPSSST 4902

Query: 1653 MDTSEAAATV 1662
            + T+   A +
Sbjct: 4903 VGTTRTPAVL 4912



 Score =  163 bits (413), Expect = 1e-39
 Identities = 366/1547 (23%), Positives = 528/1547 (34%), Gaps = 217/1547 (14%)

Query: 365  PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANP 424
            P       V   T +   + G+VAT  S         +P T  T  + TP+  P     P
Sbjct: 3274 PETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP 3333

Query: 425  PKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT---VPGSSISVPTAARTQ 481
                 P   +    P T+ G T+ P + P    T T+    T     GS  +  ++ +T 
Sbjct: 3334 -----PVWISTTTTPTTR-GSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS 3387

Query: 482  GVPAVLKVTGPQAT-TGTPLVTMRPASQAGKAPV-----TVTSLPAGVRMVVPTQSAQGT 535
            G P  L  T    T TG+   T  P+S  G  P+     T  + PA     V   SA GT
Sbjct: 3388 GTPPSLTTTATTITATGS---TTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGT 3444

Query: 536  VIGSSPQMSGMAALAAAAAATQKIPPSSAPTV----LSVPAG----TTIVKTMAVTPGTT 587
                +P +        A    + +PPSS  TV     S  +G    T I +   VT  T 
Sbjct: 3445 T--HTPPVPN----TTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTP 3498

Query: 588  TLPATVKVASSPVMVS-NPATRMLK--------TAAAQVGTSVSSATNTSTRPIITVHKS 638
                +    S+P + S +P++R  +        T     GTS ++AT T ++   +    
Sbjct: 3499 AATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLP 3558

Query: 639  GTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSA----LISNLGKVMSVVQTKPVQT 694
             + T A    VVTT           +     +PG S       SN+      V  +P+  
Sbjct: 3559 SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGL 3618

Query: 695  SAVTGQASTG-PVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIIT---TTQASGAGTKPT 749
                 QA  G P+ ++ Q  +  L  G + +      GK                G  P+
Sbjct: 3619 EC-RAQAQPGVPLRELGQVVECSLDFGLVCRNREQV-GKFKMCFNYEIRVFCCNYGHCPS 3676

Query: 750  ILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITII-----TTKVM 804
                SS +  ++ PGTT I+  +  +A  T+  +TG T++P      T I     TT  +
Sbjct: 3677 TPATSSTATPSSTPGTTWILTKLTTTATTTE--STGSTATPSSTPGTTWILTEPSTTATV 3734

Query: 805  TSGTGAPAKIITAVPKIATGHGQQGVTQVVL---KGAP-GQPGTILRTVPMGGVRLVTPV 860
            T  TG+ A   +      T H     T   +   K  P   PGT    +P       TP 
Sbjct: 3735 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGT-ATALPALRSTATTPT 3793

Query: 861  TVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLS 920
              S      ++L   GTT      T T T + S A       +A  +T +TT  T    +
Sbjct: 3794 ATSFTAIPSSSL---GTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRAT 3850

Query: 921  SQVINPTAITVSAAQT---TLTAAGGLTTP-----TITMQPVSQPTQVTLITAPSGVEAQ 972
              V  P++   +A  T   T T  G   TP     T    PV   T  T  T+ S V   
Sbjct: 3851 GSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTV--- 3907

Query: 973  PVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPP--CETHETGTTNTAT 1030
                 P S+  +  T     T T   +      P + T     PP    T  T T   +T
Sbjct: 3908 ----TPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGST 3963

Query: 1031 TTVVANLGGHPQPTQVQFVCDRQEAAASLVT--STVGQQNGSVVRVCSNPPCETH----- 1083
            T   +  G  P P  +        A +S VT  S +G  +   V    N    TH     
Sbjct: 3964 TNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV---PNTTATTHGRSLS 4020

Query: 1084 --ETGTTNTA-TTATSNMAG-------QHGCSNPPCETHETGTTNTATTAMSSVGANHQR 1133
                 T  TA T+ATS   G         G S+ P  T  TGTT  +T A+SS   +  R
Sbjct: 4021 PSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT--TGTTQHSTPALSSPHPS-SR 4077

Query: 1134 DARRACAAGTPAVIRISVATGALEAAQGSKSQCQT----RQTSATSTTMTVMATGAPCS- 1188
                  + GT      +  +     A  SK++  T      TSA  TT+        C+ 
Sbjct: 4078 TTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAW 4137

Query: 1189 ------AGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAM 1242
                  + P+ GPS     GG    +       S +R +  ++ + P G    A +   +
Sbjct: 4138 SEWLDYSYPMPGPS-----GGDFDTY-------SNIRAAGGAVCEQPLGLECRAQAQPGV 4185

Query: 1243 TRSSVG------------------AGEPRMA------------PVCESLQGGS----PST 1268
                +G                   G+ +M               C S    S    PS+
Sbjct: 4186 PLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSS 4245

Query: 1269 TVTVTALEALLCPSATVTQVCSNPPCETHETGT-------TNTATTSNAGSAQRVCSNPP 1321
            T   T +   L  +AT T    +    +   GT       T+ ATT  A S++   S+ P
Sbjct: 4246 TPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSP 4305

Query: 1322 -----------CETHETGTTHTATTATSNGGTGQ-PEGGQQPPAG----RPCETHQTTST 1365
                         T  T T+ T   +++ G TG  PE    P A      P  T +TT T
Sbjct: 4306 RTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHT 4365

Query: 1366 GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425
             T ++    A    ATSS  T  S        +    A T   A  PT    S P     
Sbjct: 4366 STVLTTK--ATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWI 4423

Query: 1426 ETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT 1485
             T  T TATT  S  S+    P +      + +    +  +T  +  T T SST   A T
Sbjct: 4424 LTELTTTATTTASTGST--ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGT 4481

Query: 1486 ---TVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTAL---------MGESAE 1533
               + T +TP    S   P     SPG    LP  +   +  TA          +G +  
Sbjct: 4482 PHVSTTATTPTVTSSKATPSS---SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWT 4538

Query: 1534 VLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMA 1593
             LS + TP         ST  PSS  E+  ++ V T        T S     S P     
Sbjct: 4539 RLSQTTTP-----TATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHT 4593

Query: 1594 EAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPM 1653
                 TTT   T  TP     TA       +  T         +       ++ GT    
Sbjct: 4594 TKVPTTTTTGFTA-TPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTH-- 4650

Query: 1654 DTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLP 1713
                   T T    G ++      Q +  P  LT               +         P
Sbjct: 4651 TARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGT---TP 4707

Query: 1714 TEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNT 1760
               +  + +    A  S   +  +    +T+ +L STAT+S A S T
Sbjct: 4708 ITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFT 4754



 Score =  161 bits (407), Expect = 7e-39
 Identities = 300/1274 (23%), Positives = 448/1274 (35%), Gaps = 180/1274 (14%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            P+T AT+++ TP+  P       +    AA   A    T +  +  P  AP P   T+  
Sbjct: 2975 PSTPATSSTATPSSTPGTTWILTEQTT-AATTTATTGSTAIPSST-PGTAPPPKVLTSTA 3032

Query: 463  VLPTVPGSSISVPTAARTQGVPAVLKVTGPQ--ATTGTPLVTMRPASQAGKAPVTVTSLP 520
              PT   S  +  ++ RT     VL  T  +  AT+ TP+ +       G  P   T+  
Sbjct: 3033 TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSF-TLGTTGTLPEQTTTPM 3091

Query: 521  AGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580
            A +  + P+         S+P+ +  + +    A T +   SS  T  S P GTT + T 
Sbjct: 3092 ATMSTIHPS---------STPETTHTSTVLTTKATTTR-ATSSMSTPSSTP-GTTWILTE 3140

Query: 581  AVTPGTTTLPA--TVKVASSP---VMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635
              T  TTT     T   +S+P    +++ P+T    TA   V T  S+AT +STR     
Sbjct: 3141 LTTAATTTAATGPTATPSSTPGTTWILTEPST----TATVTVPTG-STATASSTRA---- 3191

Query: 636  HKSGTVTVAQQAQVVTTVVG---------GVTKTITLVKSPISVPGGSALISNLGKVMSV 686
              +GT+ V        TV+          G    +  ++S  + P  +++ +     +  
Sbjct: 3192 -TAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGT 3250

Query: 687  VQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGT 746
              T+  QT+  T   ST   +   +T       T     T A G   T  +T   +    
Sbjct: 3251 AWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTK 3310

Query: 747  KPTILGISSVSPSTTKPGTT-TIIKTIPMSAIITQAGATGVTSS-PGIKSPITIITTKVM 804
             PT       +  ++ PGT  T    I  +   T  G+T   SS PG     T++TT   
Sbjct: 3311 VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT 3370

Query: 805  TSGTGAPAKIITAVPKIATGHG-QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVS 863
            T  TG+ A   ++     T        T +   G+   P +   T P+  V   T  T +
Sbjct: 3371 TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA 3430

Query: 864  AVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQV 923
            A    VT     GTT    +   T T          H  S   ++P T      + +S +
Sbjct: 3431 ATSSTVTPSSALGTTHTPPVPNTTATT---------HGRSLPPSSPHTVRTAWTSATSGI 3481

Query: 924  INPTAITVSAAQTTLTAAGGLTTPTITMQPVS--QPTQVTLITAPSGVEAQPVHDLPVSI 981
            +  T IT  +  T+ T A   +T   +   +S   P+  T  + PS     P H    S 
Sbjct: 3482 LGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSR 3541

Query: 982  LASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHE------------TGTTNTA 1029
              +  T   T T T+  S        TV      P C   E             G  +T 
Sbjct: 3542 TTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTY 3601

Query: 1030 TTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQ---------------QNGSVVRV 1074
            +    A      QP  ++    R +A   +    +GQ               +     ++
Sbjct: 3602 SNIRAAGGAVCEQPLGLEC---RAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKM 3658

Query: 1075 CSNPPCET------HETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVG 1128
            C N           H   T  T++TAT +       S P      T  T TATT  S+  
Sbjct: 3659 CFNYEIRVFCCNYGHCPSTPATSSTATPS-------STPGTTWILTKLTTTATTTESTGS 3711

Query: 1129 ANHQRDARRACAAGTPAVI-------RISVATGALEAAQGSKSQCQTRQTSATSTTMTVM 1181
                  A  +   GT  ++        ++V TG+   A  +++   T   S T+TT TV 
Sbjct: 3712 T-----ATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVT 3766

Query: 1182 ATGAPCSAGPLLGPSMARE-PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTA 1240
            ++     A P   P  A   P  RS A             ++P+           A S  
Sbjct: 3767 SS----KATPFSSPGTATALPALRSTA-------------TTPT-----------ATSFT 3798

Query: 1241 AMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETG 1300
            A+  SS+G    R+            S T T TA  +   PS+T       P      T 
Sbjct: 3799 AIPSSSLGTTWTRL------------SQTTTPTATMSTATPSST-------PETAHTSTV 3839

Query: 1301 TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH 1360
             T TATT+ A  +    S+ P   H T    T TT  +   +  P   + PP      T 
Sbjct: 3840 LTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTT 3899

Query: 1361 QTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNP 1420
             TTS  T    SV       T    T  +   VA     TP + T            S  
Sbjct: 3900 PTTSGSTVTPSSVPGTTHTPTVLTTTTTT---VATGSMATPSSSTQ----------TSGT 3946

Query: 1421 PCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVEST-QGDSVNITSSSAITTTVSST 1479
            P     T TT TAT  T+N SS     P         +T    S  +T SSA+ TT +  
Sbjct: 3947 PPSLITTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPP 4006

Query: 1480 LTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQ-SASTALMGESAEVLSAS 1538
            +    TT T       PS P       +      L    + + S  T+    +    +  
Sbjct: 4007 VPN--TTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQH 4064

Query: 1539 QTPELPAAVDLSSTGE--PSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQ 1596
             TP L +    S T E  PS G  + G     +       P+++    L LP    +   
Sbjct: 4065 STPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTL-LPS---SPTS 4120

Query: 1597 AGTTTLMVTGLTPE 1610
            A  TT++ TG  P+
Sbjct: 4121 APITTVVTTGCEPQ 4134



 Score =  159 bits (401), Expect = 3e-38
 Identities = 370/1575 (23%), Positives = 540/1575 (34%), Gaps = 258/1575 (16%)

Query: 365  PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANP 424
            P  A    V   T +   + G+VAT  S         +P T  T  + TP+  P     P
Sbjct: 2017 PETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP 2076

Query: 425  PKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT---VPGSSISVPTAARTQ 481
                 P   +    P T+ G T+ P + P    T T+    T     GS  +  ++ +T 
Sbjct: 2077 -----PVWISTTTTPTTR-GSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTS 2130

Query: 482  GVPAVLKVTGPQAT-TGTPLVTMRPASQAGKAPV-----TVTSLPAGVRMVVPTQSAQGT 535
            G P  L  T    T TG+   T  P+S  G  P+     T  + PA     V   SA GT
Sbjct: 2131 GTPPSLTTTATTITATGS---TTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGT 2187

Query: 536  VIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT--IVKTMAVTPGTT----TL 589
               + P  + MA         + +PPSS  TV +     T  I+ T  +T  +T    TL
Sbjct: 2188 T-HTPPVPNTMATTHG-----RSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTL 2241

Query: 590  PATVKVA--SSPVMVS-NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQ 646
             AT      S+P + S +P++R  ++  +  GT+    T  ++R   T   S T T    
Sbjct: 2242 AATTGTTQHSTPALSSPHPSSRTTESPPSP-GTTTPGHTTATSRTTATATPSKTRTSTLL 2300

Query: 647  AQVVTTVVGGVTKTITLVKSP-----------ISVPGGSA----LISNLGKVMSVVQTKP 691
                T+    +T  +T+   P             +PG S       SN+      V  +P
Sbjct: 2301 PSSPTS--APITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQP 2358

Query: 692  VQTSAVTGQASTG-PVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIIT---TTQASGAGT 746
            +       QA  G P+ ++ Q  +  L  G + +      GK                G 
Sbjct: 2359 LGLEC-RAQAQPGVPLRELGQVVECSLDFGLVCRNREQV-GKFKMCFNYEIRVFCCNYGH 2416

Query: 747  KPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITII-----TT 801
             P+    SS +  ++ PGTT I+  +  +A  T+  +TG T++P      T I     TT
Sbjct: 2417 CPSTPATSSTAMPSSTPGTTWILTELTTTATTTE--STGSTATPSSTPGTTWILTEPSTT 2474

Query: 802  KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVT 861
              +T  TG+ A   +      T H     T   +  +   P               +P T
Sbjct: 2475 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP-------------FSSPGT 2521

Query: 862  VSAVKPAVTTLVVKGTTGVTTL-GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLS 920
             +A+    +T      T  T +  +  GT  T L+     + + S ATP +T  T+ T  
Sbjct: 2522 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHT-- 2579

Query: 921  SQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQP------V 974
            S V+  TA       TT  A G + TP+ T  P +  T   L T  +G  A P       
Sbjct: 2580 STVLTTTA-------TTTGATGSVATPSST--PGTAHTTKVLTTTTTGFTATPSSSPGTA 2630

Query: 975  HDLPV--SILASPTTE------------------QPTATVTIADSGQGDVQPGTVTLVCS 1014
              LPV  S   +PTT                     T T T+A        P + T    
Sbjct: 2631 RTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM--ATPSSSTQTSG 2688

Query: 1015 NPPCETHETGTTNTA---TTTVVANLGGHPQPTQVQFVCDRQEAAASLVT--STVGQQNG 1069
             PP  T  T TT TA   TT   +  G  P P  +        A +S VT  S +G  + 
Sbjct: 2689 TPPSLT-TTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHT 2747

Query: 1070 SVVRVCSNPPCETH-------ETGTTNTA-TTATSNMAG-------QHGCSNPPCETHET 1114
              V    N    TH          T  TA T+ATS   G         G S+ P  T  T
Sbjct: 2748 PPV---PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT--T 2802

Query: 1115 GTTNTATTAMSSV-GANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT----R 1169
            GTT  +T A+SS   ++   ++  +    TP   R +  T A   A  SK++  T     
Sbjct: 2803 GTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTA--TATPSKTRTSTLLPSS 2860

Query: 1170 QTSATSTTMTVMATGAPCS-------AGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSS 1222
             TSA  TT+  M     C+       + P+ GPS     GG    +       S +R + 
Sbjct: 2861 PTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPS-----GGDFDTY-------SNIRAAG 2908

Query: 1223 PSIKDLPAGRHSHAVSTAAMTRSSVG---AGEPRMAPVCESLQGGSPSTTVTVTALEALL 1279
             ++ + P G    A +   +    +G           VC + +            +    
Sbjct: 2909 GAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFC 2968

Query: 1280 C-----PSATVTQVCSNPPCETHET-----GTTNTATTSNAGSAQRVCSNPPCETHETGT 1329
            C     PS   T   + P      T      TT   TT+  GS     S P         
Sbjct: 2969 CNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVL 3028

Query: 1330 THTATTATSNGGTGQPEGGQQPPAGRPCETHQTT-STGT------TMSVSVGALLPDATS 1382
            T TATT T+           +     P  T   T ST T      + ++     LP+ T+
Sbjct: 3029 TSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTT 3088

Query: 1383 SHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSS 1442
            +     S +  ++ P  T    T L     T R  S+    +   GTT   T +T+  ++
Sbjct: 3089 TPMATMSTIHPSSTPETT-HTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3147

Query: 1443 NQDPPPAASDQGEVEST-----QGDSVNITSSSAITTTVSSTLTRA----VTTVTQSTPV 1493
                 P A+      +T        +  +T  +  T T SST   A    V T T +TP 
Sbjct: 3148 TAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT 3207

Query: 1494 PGPSVPPPEELQVSPGPRQQLPPRQLLQSASTAL---------MGESAEVLSASQTPELP 1544
               S   P     SPG    LP  +   +  TA          +G +   LS + TP   
Sbjct: 3208 VISSRATPSS---SPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTP--- 3261

Query: 1545 AAVDLSSTGEPSSGQESAGSAVV---------ATVVVQPPPPTQSEVDQLSLPQELMAEA 1595
                  ST  PSS  E+  ++ V         AT  V  P  T        +P       
Sbjct: 3262 --TATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 3319

Query: 1596 QA-----------------GTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAV 1638
             A                  TTT    G T    ++      A     T    A    A 
Sbjct: 3320 TATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT 3379

Query: 1639 LQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQ 1698
              ++ Q    +G P   +  A T+T    G  +        T IP VLT           
Sbjct: 3380 PSSSTQT---SGTPPSLTTTATTITAT--GSTTNPSSTPGTTPIPPVLTTTATTPAATSS 3434

Query: 1699 QLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPS 1758
             +  + A    H  P          N  A        L  + P TV    ++AT  +  +
Sbjct: 3435 TVTPSSALGTTHTPPVP--------NTTATTHG--RSLPPSSPHTVRTAWTSATSGILGT 3484

Query: 1759 NTFVAPQPVVVASPA 1773
                 P  V   +PA
Sbjct: 3485 THITEPSTVTSHTPA 3499



 Score =  146 bits (369), Expect = 2e-34
 Identities = 319/1363 (23%), Positives = 459/1363 (33%), Gaps = 234/1363 (17%)

Query: 465  PTVPGSSISVPTAARTQGVPAVL-KVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGV 523
            P+ P +S S  T + T G   +L K+T    TT +   T  P+S  G   +         
Sbjct: 3675 PSTPATS-STATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWI--------- 3724

Query: 524  RMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVT 583
             +  P+ +A  TV       +G  A A++  AT   P  S  T  + P  T+   T   +
Sbjct: 3725 -LTEPSTTATVTV------PTGSTATASSTQATAGTPHVS--TTATTPTVTSSKATPFSS 3775

Query: 584  PGTTT-LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVS--SATNTSTRPIITVHKSGT 640
            PGT T LPA    A++P      AT      ++ +GT+ +  S T T T  + T   S T
Sbjct: 3776 PGTATALPALRSTATTPT-----ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSST 3830

Query: 641  VTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ 700
               A  + V+TT     T+    V +P S PG                T  V T+  TG 
Sbjct: 3831 PETAHTSTVLTTTAT-TTRATGSVATPSSTPG-------------TAHTTKVPTTTTTGF 3876

Query: 701  ASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPST 760
              T        +  P  A T           P   I+TT      T PT  G S+V+PS+
Sbjct: 3877 TVT-------PSSSPGTART-----------PPVWISTT------TTPTTSG-STVTPSS 3911

Query: 761  TKPGTT--TIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818
              PGTT    + T   + + T + AT  +S+    +P ++ITT    + TG+        
Sbjct: 3912 V-PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTT------ 3964

Query: 819  PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT 878
                                   P +   T P+  V   T  T +A    VT     GTT
Sbjct: 3965 ----------------------NPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTT 4002

Query: 879  GVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTL 938
                +   T T          H  S S ++P T      + +S  +  T IT  +  T+ 
Sbjct: 4003 HTPPVPNTTATT---------HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSH 4053

Query: 939  TAAG--GLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTI 996
            T A   G T  +        P+  T  + PS     P H    S   +  T   T T T+
Sbjct: 4054 TPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTL 4113

Query: 997  ADSGQGDVQPGTVTLVCSNPPCETHE------------TGTTNTATTTVVANLGGHPQPT 1044
              S        TV      P C   E             G  +T +    A      QP 
Sbjct: 4114 LPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPL 4173

Query: 1045 QVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGC 1104
             ++     Q          V + +     VC N      + G          N   +  C
Sbjct: 4174 GLECRAQAQPGVPLGELGQVVECSLDFGLVCRN----REQVGKFKMC----FNYEIRVFC 4225

Query: 1105 SNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKS 1164
             N     H   T  T++TAM S               GT  ++     T    A+ GS  
Sbjct: 4226 CN---YGHCPSTPATSSTAMPS------------STPGTTWILTELTTTATTTASTGS-- 4268

Query: 1165 QCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPS 1224
                     T+T  +   T  P        P +   P     A    A  SS  R ++  
Sbjct: 4269 ---------TATPSSTPGTAPP--------PKVLTSPATTPTATSSKATSSSSPRTATTL 4311

Query: 1225 IKDLPAGRHSHAVSTAAMTRSSVGA----GEPRMAPVCESLQGGSPSTTVTVTALEALLC 1280
                     S A S   +  S++G      E    PV  ++    PS+T   T    +L 
Sbjct: 4312 PVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVA-TMSTIHPSSTPETTHTSTVLT 4370

Query: 1281 PSATVTQVCSNPPCETHETGTT------NTATTSNA--GSAQRVCSNPPCETHETGTTHT 1332
              AT T+  S+    +   GTT       TA T+ A  G      S P      T  T T
Sbjct: 4371 TKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTT 4430

Query: 1333 ATTATSNGGTGQPEGG-------QQP--------PAGRPCETHQTTSTGTTMSVSVGALL 1377
            ATT  S G T  P           +P        P G       T +T  T  VS  A  
Sbjct: 4431 ATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATT 4490

Query: 1378 PDATSSHRTVESGLEVAAA-PSVTPQAGTALLAPFPTQRVCSNPPCETH-ETGTTHTATT 1435
            P  TSS  T  S    A A P++   A T     F      S     T     TT TAT 
Sbjct: 4491 PTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATM 4550

Query: 1436 VTSNMSSNQDPPPAASDQGEVESTQGDSVNI-----TSSSAITTTVSSTLTRAVTTVTQS 1490
             T+  SS  +    ++      +T G + ++     T  +A TT V +T T   T    S
Sbjct: 4551 STATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSS 4610

Query: 1491 TPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMG--ESAEVLSASQTPELPAAVD 1548
            +  PG ++ PP  +  +  P    P         +++ G   +A VL+ + T      V 
Sbjct: 4611 S--PGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTT-----TVA 4663

Query: 1549 LSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLT 1608
              S   PSS  +++G+    T        T S  +  S P         GTT +    LT
Sbjct: 4664 TGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTP---------GTTPITPV-LT 4713

Query: 1609 PEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELG 1668
                   A +  A  +++   A  L +         A   T  P  T     TV      
Sbjct: 4714 STATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTT 4773

Query: 1669 HLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAI 1728
             +S       ++T     T   L       +   + A             P+ +L    I
Sbjct: 4774 PMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTA------------TPSSTLGTTRI 4821

Query: 1729 ESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVAS 1771
                L EL  T  +T A   STAT S  P  T++  +P  +A+
Sbjct: 4822 ----LTELT-TTATTTAATGSTATLSSTPGTTWILTEPSTIAT 4859



 Score =  144 bits (363), Expect = 9e-34
 Identities = 291/1345 (21%), Positives = 444/1345 (33%), Gaps = 202/1345 (15%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            P  ++  T   P+P  + P +   +    A A   +  T    TLLP +  + P TT + 
Sbjct: 2258 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS---TLLPSSPTSAPITTVVT 2314

Query: 463  V-----------------LPTVPGSSISVPTAARTQGVPAVLKVTG----PQATTGTPL- 500
            +                 +P   G      +  R  G     +  G     QA  G PL 
Sbjct: 2315 MGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLR 2374

Query: 501  -------------VTMRPASQAGKAPVTVT--------------SLPAGVRMVVPTQS-- 531
                         +  R   Q GK  +                 S PA     +P+ +  
Sbjct: 2375 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPG 2434

Query: 532  -----AQGTVIGSSPQMSGMAALAAAAAATQKI--PPSSAPTVLSVPAGTTIVKTMAVTP 584
                  + T   ++ + +G  A  ++   T  I   PS+  TV +VP G+T   T + T 
Sbjct: 2435 TTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV-TVPTGSTA--TASSTQ 2491

Query: 585  GTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVA 644
             T   P     A++P + S+ AT       A    ++ S   T T    T   S ++   
Sbjct: 2492 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 2551

Query: 645  QQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG 704
                  TT       T T    P S P               V T  V T+  T   +TG
Sbjct: 2552 WTRLSQTTTPTATMSTAT----PSSTP-------------ETVHTSTVLTTTATTTGATG 2594

Query: 705  PVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPG 764
             V     T G   A T   L T+     TT  T T +S  GT  T+    S + + T  G
Sbjct: 2595 SVATPSSTPGT--AHTTKVLTTT-----TTGFTATPSSSPGTARTLPVWISTTTTPTTRG 2647

Query: 765  TTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATG 824
            +T    +IP           G T +P      T++TT   T  TG+ A   ++     T 
Sbjct: 2648 STVTPSSIP-----------GTTHTP------TVLTTTTTTVATGSMATPSSSTQTSGTP 2690

Query: 825  HG-QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883
                   T +   G+   P +   T P+  V   T  T +A    VT     GTT    +
Sbjct: 2691 PSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 2750

Query: 884  GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG- 942
               T T          H  S S ++P T      + +S  +  T IT  +  T+ T A  
Sbjct: 2751 PNTTATT---------HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 2801

Query: 943  -GLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G T  +        P+  T  + PS     P H    S   +  T   T T T+  S  
Sbjct: 2802 TGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSP 2861

Query: 1002 GDVQPGTVTLVCSNPPCETHE------------TGTTNTATTTVVANLGGHPQPTQVQFV 1049
                  TV  +   P C   E             G  +T +    A      QP  ++  
Sbjct: 2862 TSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECR 2921

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPP----------------CETHETGTTNTATT 1093
               Q          V + +     VC N                  C  +    +  AT+
Sbjct: 2922 AQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS 2981

Query: 1094 ATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVAT 1153
            +T+  +   G +    E   T  T TATT  +++ ++           GT    ++  +T
Sbjct: 2982 STATPSSTPGTTWILTE-QTTAATTTATTGSTAIPSS---------TPGTAPPPKVLTST 3031

Query: 1154 GALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAP 1213
                 A  SK+   +  +  T+TT+ V+ + A  S      P  +   G       Q   
Sbjct: 3032 ATTPTATSSKA--TSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTT 3089

Query: 1214 LSSKVRLSSPSIKDLPAGRHSHAVST--AAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
              + +    PS    P   H+  V T  A  TR++     P   P    +     +   T
Sbjct: 3090 PMATMSTIHPS--STPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3147

Query: 1272 VTALEALLCPSAT--VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGT 1329
              A      PS+T   T + + P   T  T T  T +T+ A S +               
Sbjct: 3148 TAATGPTATPSSTPGTTWILTEP--STTATVTVPTGSTATASSTRATAGTLKV------L 3199

Query: 1330 THTATTATSNGGTGQPEGGQQPPAGRPC-ETHQTTSTGTTMSVSVGALLPDATS--SHRT 1386
            T TATT T       P          P   +  TT T T+++    + L  A +  S  T
Sbjct: 3200 TSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3259

Query: 1387 VESGLEVAAAPSVTPQ---AGTALLAPFPTQRVCSNPPCETHETGTTHTA---TTVTSNM 1440
              +     A PS TP+     T L     T R   +    +   GT HT    TT T+  
Sbjct: 3260 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 3319

Query: 1441 SSNQD-------PPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPV 1493
            ++           PP         +T+G +V  T SS   TT ++T    V T T +T  
Sbjct: 3320 TATPSSSPGTALTPPVWISTTTTPTTRGSTV--TPSSIPGTTHTAT----VLTTTTTTVA 3373

Query: 1494 PGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTG 1553
             G    P    Q S       PP     + +    G +    S   T  +P  +  ++T 
Sbjct: 3374 TGSMATPSSSTQTS-----GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATT 3428

Query: 1554 EPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSL----PQELMAEAQAGTTTLMVTGLTP 1609
              ++      S+ + T    P P T +     SL    P  +     + T+ ++ T    
Sbjct: 3429 PAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHIT 3488

Query: 1610 EELAVTAAAEAAAQAAATEEAQALA 1634
            E   VT+   AA  +       AL+
Sbjct: 3489 EPSTVTSHTPAATTSTTQHSTPALS 3513



 Score =  137 bits (344), Expect = 1e-31
 Identities = 316/1441 (21%), Positives = 487/1441 (33%), Gaps = 267/1441 (18%)

Query: 325  HCAVAINTRLYIWSGRDGYRKAWNNQV---CCKDLWYLETEKPPPPARVQLVRANTNSLE 381
            HC V        W     ++  +N ++   CC D         PPP         T  LE
Sbjct: 1570 HCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPP---------TTELE 1620

Query: 382  VSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLT 441
                                   TA T T+      P   ++P  + AP A+  AV  L+
Sbjct: 1621 -----------------------TATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLS 1657

Query: 442  QVGIT------LLPQAAPAPPTTTTIQVLPTVPGSSIS-VPTAARTQGVPAVLKVTGPQA 494
            + G+T       L  A    PTT      PTVPG + S +PT +   G            
Sbjct: 1658 E-GLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVATSTLPTRSALPG------------ 1704

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TTG+ L T RP+     AP T+ +  A       T S +      +P ++   + + A  
Sbjct: 1705 TTGS-LGTWRPSQPPTLAPTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAET 1763

Query: 555  ATQKIPPSSAP-TVLSVPAGTTIVK--------------TMAVTPGTTTLPATVKVAS-- 597
            +T +   + +P T  +   GTT  +              T  V  G       ++ A   
Sbjct: 1764 STPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGK 1823

Query: 598  ---SPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVV 654
               +P  +   A    + +  QVG  ++ +  T         ++G   +     V     
Sbjct: 1824 MCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGL-TCKNEDQTGRFNMCFNYNVRVLCC 1882

Query: 655  GGV-----TKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ-ASTGPVTQ 708
                    T   +   +P S PG + ++           TKP  T+  T    ST   T 
Sbjct: 1883 DDYSHCPSTPATSSTATPSSTPGTTWIL-----------TKPTTTATTTASTGSTATPTS 1931

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
             ++T  P       K++T+    PT  +T+++A+ + +  T   + ++  + T P T T 
Sbjct: 1932 TLRTAPP------PKVLTTTATTPT--VTSSKATPSSSPGTATALPALRSTATTP-TATS 1982

Query: 769  IKTIPMSAI---------ITQAGATGVTSSPGIKSPITIITTKVMT---SGTGAPAKIIT 816
            +  IP S++          T   AT  T++P   +P T  T+ V+T   + TGA   + T
Sbjct: 1983 VTPIPSSSLGTTWTRLSQTTTPTATMSTATPS-STPETAHTSTVLTATATTTGATGSVAT 2041

Query: 817  AVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG 876
                  T H  + V      G    P +   T     V + T  T +     VT   + G
Sbjct: 2042 PSSTPGTAHTTK-VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG 2100

Query: 877  TT-GVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQ 935
            TT   T L T T TV+T            S+ATP ++  T  T       P ++T +A  
Sbjct: 2101 TTHTATVLTTTTTTVAT-----------GSMATPSSSTQTSGT-------PPSLTTTA-- 2140

Query: 936  TTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVT 995
            TT+TA G  T P+ T  P + P    L T  +   A      P S L   TT  P    T
Sbjct: 2141 TTITATGSTTNPSST--PGTTPIPPVLTTTATTPAATSNTVTPSSALG--TTHTPPVPNT 2196

Query: 996  IADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEA 1055
            +A            T   S PP   H   T  TA T+  + + G    T+   V     A
Sbjct: 2197 MA-----------TTHGRSLPPSSPH---TVRTAWTSATSGILGTTHITEPSTVTSHTLA 2242

Query: 1056 AASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETG 1115
            A                            TGTT  +T A S+              H + 
Sbjct: 2243 AT---------------------------TGTTQHSTPALSS-------------PHPSS 2262

Query: 1116 TTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATS 1175
             T  +  +  +    H     R  A  TP+  R S             +   +  TSA  
Sbjct: 2263 RTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS-------------TLLPSSPTSAPI 2309

Query: 1176 TTMTVMATGAPCS-------AGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDL 1228
            TT+  M     C+       + P+ GPS     GG    +       S +R +  ++ + 
Sbjct: 2310 TTVVTMGCEPQCAWSEWLDYSYPMPGPS-----GGDFDTY-------SNIRAAGGAVCEQ 2357

Query: 1229 PAGRHSHAVSTAAMTRSSVG---AGEPRMAPVCESLQGGSP-----STTVTVTALEALLC 1280
            P G    A +   +    +G           VC + +         +  + V       C
Sbjct: 2358 PLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC 2417

Query: 1281 PSATVTQVCSNPPCETHETG-----TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATT 1335
            PS   T   + P      T      TT   TT + GS     S P      T  + TAT 
Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 2477

Query: 1336 ATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAA 1395
                G T       Q  AG P  +   T+   T S +     P   ++   + S      
Sbjct: 2478 TVPTGSTA-TASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPT 2536

Query: 1396 APSVTPQAGTALLAPF--------PTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPP 1447
            A S T    ++L   +        PT  + +  P  T E  T HT+T +T+  ++     
Sbjct: 2537 ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE--TVHTSTVLTTTATTTGATG 2594

Query: 1448 PAASDQGEVESTQGDSVNITSSSAITTTVSST----LTRAVTTVTQSTPVPGPSVPPPEE 1503
              A+      +     V  T+++  T T SS+     T  V   T +TP    S   P  
Sbjct: 2595 SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSS 2654

Query: 1504 LQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAG 1563
            +     P     P  L  + +T   G  A   S++QT   P ++  ++T   ++G  +  
Sbjct: 2655 I-----PGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNP 2709

Query: 1564 SAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQ 1623
            S+   T  + PP  T +     +    +   +  GTT    T   P   A T     +  
Sbjct: 2710 SSTPGTTPI-PPVLTTTATTPAATSSTVTPSSALGTTH---TPPVPNTTATTHGRSLSPS 2765

Query: 1624 AAAT-EEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTI 1682
            +  T   A   A    L         TG    T  A    TQ     LS+     + T  
Sbjct: 2766 SPHTVRTAWTSATSGTLGTTHITEPSTG-TSHTPAATTGTTQHSTPALSSPHPSSRTTES 2824

Query: 1683 P 1683
            P
Sbjct: 2825 P 2825



 Score =  134 bits (337), Expect = 9e-31
 Identities = 345/1572 (21%), Positives = 518/1572 (32%), Gaps = 305/1572 (19%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            + T ++ V  G+ ATA S   +     +    +TAT+PT   V S  A P  SP  A A 
Sbjct: 3171 STTATVTVPTGSTATASS--TRATAGTLKVLTSTATTPT---VISSRATPSSSPGTATAL 3225

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT-------VPGSSISVPTAARTQGVPAVL 487
            PA++            +    PT T++  +P+          S  + PTA  +   P+  
Sbjct: 3226 PALR------------STATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSST 3273

Query: 488  KVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMV-VPTQSAQG-TVIGSSPQMSG 545
              T     T T L T    ++A  +  T +S P       VPT +  G T   SS   + 
Sbjct: 3274 PET---VHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTA 3330

Query: 546  MAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNP 605
            +      +  T      S  T  S+P GTT   T+  T  TTT  AT  +A+        
Sbjct: 3331 LTPPVWISTTTTPTTRGSTVTPSSIP-GTTHTATVLTT--TTTTVATGSMATPSSSTQTS 3387

Query: 606  ATRMLKTAAAQVGTSVSSATNTSTRPIIT-----VHKSGTVTVAQQAQVVTTVVGGVTKT 660
             T    T  A   T+  S TN S+ P  T     +  + T   A  + V  +   G T T
Sbjct: 3388 GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHT 3447

Query: 661  ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720
              +  +  +  G S   S+   V      +   TSA +G   T  +T+        PA T
Sbjct: 3448 PPVPNTTATTHGRSLPPSSPHTV------RTAWTSATSGILGTTHITEPSTVTSHTPAAT 3501

Query: 721  ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780
                 TS     T  +++   S   T+      S  SP TT PG T              
Sbjct: 3502 -----TSTTQHSTPALSSPHPSSRTTE------SPPSPGTTTPGHT------------RG 3538

Query: 781  AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG 840
               T  T++P      T  +T + +S T AP   IT V  + TG   Q      L  +  
Sbjct: 3539 TSRTTATATPS----KTRTSTLLPSSPTSAP---ITTV--VTTGCEPQCAWSEWLDYSYP 3589

Query: 841  QPG-------TILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTS 893
             PG       T       GG     P+ +     A   + ++    V       G V  +
Sbjct: 3590 MPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRN 3649

Query: 894  LAGAG-----------------GHSTS----ASLATPITTLGTIATLSSQVINPTAITVS 932
                G                 GH  S    +S ATP +T GT   L+   +  TA T  
Sbjct: 3650 REQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTK--LTTTATTTE 3707

Query: 933  AAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA 992
            +  +T T +   +TP  T   +++P+    +T P+G  A        +     +T   T 
Sbjct: 3708 STGSTATPS---STPGTTW-ILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTP 3763

Query: 993  TVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDR 1052
            TVT +        PGT T + +        T TT TAT+                     
Sbjct: 3764 TVT-SSKATPFSSPGTATALPA-----LRSTATTPTATSFTAI----------------- 3800

Query: 1053 QEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGC----SNPP 1108
              ++     + + Q       + +  P  T ET  T+T  T T+      G     S+ P
Sbjct: 3801 PSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTP 3860

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQC-- 1166
               H T    T TT  +   ++    AR      TP V   +  T     +  + S    
Sbjct: 3861 GTAHTTKVPTTTTTGFTVTPSSSPGTAR------TPPVWISTTTTPTTSGSTVTPSSVPG 3914

Query: 1167 QTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIK 1226
             T   +  +TT T +ATG+      +  PS + +  G  P+ +  A              
Sbjct: 3915 TTHTPTVLTTTTTTVATGS------MATPSSSTQTSGTPPSLITTA-------------- 3954

Query: 1227 DLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL------LC 1280
                   +   +T + T  S   G   + PV  +      +T+ TVT   AL        
Sbjct: 3955 -------TTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 4007

Query: 1281 PSAT-VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSN 1339
            P+ T  T   S  P   H   T  T+ TS       + + P   T  T    T TT  S 
Sbjct: 4008 PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI-TEPSTGTSHTPAATTGTTQHST 4066

Query: 1340 GGTGQPEGG----QQPPA------GRPCETHQTTSTGTTMSVSVGALLPDATSS---HRT 1386
                 P       + PP+      G    T +TT+T T        LLP + +S      
Sbjct: 4067 PALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 4126

Query: 1387 VESGLEVAAA----------------------PSVTPQAGTALLAPFPTQ-RVCSNPPCE 1423
            V +G E   A                       ++    G     P   + R  + P   
Sbjct: 4127 VTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 4186

Query: 1424 THETGTTHTAT----TVTSN--------MSSNQDPPPAASDQGEVESTQGDSVNITSSSA 1471
              E G     +     V  N        M  N +      + G   ST   S     SS 
Sbjct: 4187 LGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 4246

Query: 1472 -----ITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSAS-- 1524
                 I T +++T T   +T + +TP   P   PP ++  SP         +   S+S  
Sbjct: 4247 PGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPR 4306

Query: 1525 -----TALMGESAEVLSASQTP--------------ELPAAVDLSSTGEPSSGQESAGSA 1565
                   L   + +  + S TP              +    V   ST  PSS  E+  ++
Sbjct: 4307 TATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTS 4366

Query: 1566 VVATVVVQPPPPTQSEVDQLSLPQE--LMAEAQAGTTTLMVTGLTP------------EE 1611
             V T        T S     S P    ++ E     TT   TG T              E
Sbjct: 4367 TVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTE 4426

Query: 1612 LAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLS 1671
            L  TA   A+  + AT  +       + + +  A + T     T+ A++T   A   H+S
Sbjct: 4427 LTTTATTTASTGSTATPSSTPGTTWILTEPSTTATV-TVPTGSTATASSTQATAGTPHVS 4485

Query: 1672 AEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESN 1731
                     T P V + +                        T + +P  +   PA+ S 
Sbjct: 4486 T------TATTPTVTSSK-----------------------ATPSSSPGTATALPALRST 4516

Query: 1732 CLNELAGT---VPS-----TVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTE 1783
                 A +   +PS     T   L  T T +   S    +  P  V +   L A AT T 
Sbjct: 4517 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTG 4576

Query: 1784 VANGIESLGVKP 1795
                + +    P
Sbjct: 4577 ATGSVATPSSTP 4588



 Score =  133 bits (335), Expect = 2e-30
 Identities = 335/1527 (21%), Positives = 496/1527 (32%), Gaps = 257/1527 (16%)

Query: 377  TNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPA 436
            T +   S G+ AT  S L       +  T  TAT+PT   V S  A P  SP  A A PA
Sbjct: 1916 TATTTASTGSTATPTSTLRTAPPPKVLTT--TATTPT---VTSSKATPSSSPGTATALPA 1970

Query: 437  VQPL--TQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV-TGPQ 493
            ++    T    ++ P  + +  TT T     T P +++S  T + T        V T   
Sbjct: 1971 LRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATA 2030

Query: 494  ATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQG-TVIGSSPQMSGMAALAAA 552
             TTG       P+S  G A  T           VPT +  G T   SS   + +      
Sbjct: 2031 TTTGATGSVATPSSTPGTAHTTK----------VPTTTTTGFTATPSSSPGTALTPPVWI 2080

Query: 553  AAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKT 612
            +  T      S  T  S+P GTT   T+  T  TTT  AT  +A+         T    T
Sbjct: 2081 STTTTPTTRGSTVTPSSIP-GTTHTATVLTT--TTTTVATGSMATPSSSTQTSGTPPSLT 2137

Query: 613  AAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPG 672
              A   T+  S TN S+ P       GT  +        T     + T+T    P S  G
Sbjct: 2138 TTATTITATGSTTNPSSTP-------GTTPIPPVLTTTATTPAATSNTVT----PSSALG 2186

Query: 673  GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP 732
                            T PV  +  T    + P +     +    + T   L T+   +P
Sbjct: 2187 -------------TTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 2233

Query: 733  TTIITTTQASGAG-TKPTILGISSVSPST------TKPGTTTIIKTIPMSAIITQAGATG 785
            +T+ + T A+  G T+ +   +SS  PS+        PGTTT   T       T    T 
Sbjct: 2234 STVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHT-------TATSRTT 2286

Query: 786  VTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPG-- 843
             T++P      T  +T + +S T AP   IT V  +  G   Q      L  +   PG  
Sbjct: 2287 ATATPS----KTRTSTLLPSSPTSAP---ITTV--VTMGCEPQCAWSEWLDYSYPMPGPS 2337

Query: 844  -----TILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAG 898
                 T       GG     P+ +     A   + ++    V       G V  +    G
Sbjct: 2338 GGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVG 2397

Query: 899  -----------------GHSTS----ASLATPITTLGTIATLSSQVINPTAITVSAAQTT 937
                             GH  S    +S A P +T GT   L+   +  TA T  +  +T
Sbjct: 2398 KFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTE--LTTTATTTESTGST 2455

Query: 938  LTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIA 997
             T +   +TP  T   +++P+    +T P+G  A        +     +T   T TVT +
Sbjct: 2456 ATPS---STPGTTW-ILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVT-S 2510

Query: 998  DSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
                    PGT T + +        T TT TAT+                       ++ 
Sbjct: 2511 SKATPFSSPGTATALPA-----LRSTATTPTATSFTAI-----------------PSSSL 2548

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGC----SNPPCETHE 1113
                + + Q       + +  P  T ET  T+T  T T+   G  G     S+ P   H 
Sbjct: 2549 GTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHT 2608

Query: 1114 TGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSK-SQCQTRQTS 1172
            T    T TT  +         A  + + GT   + + ++T      +GS  +      T+
Sbjct: 2609 TKVLTTTTTGFT---------ATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTT 2659

Query: 1173 ATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR 1232
             T T +T   T    + G +  PS + +  G  P+    A                    
Sbjct: 2660 HTPTVLTTTTT--TVATGSMATPSSSTQTSGTPPSLTTTA-------------------- 2697

Query: 1233 HSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL------LCPSAT-V 1285
             +   +T + T  S   G   + PV  +      +T+ TVT   AL        P+ T  
Sbjct: 2698 -TTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTAT 2756

Query: 1286 TQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQP 1345
            T   S  P   H   T  T+ TS       + + P   T  T    T TT  S      P
Sbjct: 2757 THGRSLSPSSPHTVRTAWTSATSGTLGTTHI-TEPSTGTSHTPAATTGTTQHSTPALSSP 2815

Query: 1346 EGG----QQPPA------GRPCETHQTTSTGTTMSVSVGALLPDATSS---HRTVESGLE 1392
                   + PP+      G    T +TT+T T        LLP + +S      V  G E
Sbjct: 2816 HPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCE 2875

Query: 1393 VAAA----------------------PSVTPQAGTALLAPFPTQ-RVCSNPPCETHETGT 1429
               A                       ++    G     P   + R  + P     E G 
Sbjct: 2876 PQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQ 2935

Query: 1430 THTAT----TVTSN--------MSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTT-- 1475
                +     V  N        M  N +      + G   ST   S   T SS   TT  
Sbjct: 2936 VVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWI 2995

Query: 1476 -VSSTLTRAVTTVTQSTPVPGP---SVPPPEEL----------------QVSPGPRQQLP 1515
                T     T  T ST +P     + PPP+ L                  SP     LP
Sbjct: 2996 LTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLP 3055

Query: 1516 PRQLLQSASTALMGESAEVLSASQTPELP----AAVDLSSTGEPSSGQESAGSAVVATVV 1571
                  + STA         +   T  LP      +   ST  PSS  E+  ++ V T  
Sbjct: 3056 VLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTK 3115

Query: 1572 VQPPPPTQSEVDQLSLPQE--LMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEE 1629
                  T S     S P    ++ E     TT   TG T    +         + + T  
Sbjct: 3116 ATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTAT 3175

Query: 1630 AQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQ 1689
                       ++ +A  GT + + ++    TV  +     +     G AT +P + +  
Sbjct: 3176 VTVPTGSTATASSTRATAGTLKVLTSTATTPTVISS---RATPSSSPGTATALPALRSTA 3232

Query: 1690 EL-----AALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTV 1744
                      +    L  A  +      PT  ++ A   + P  E+   + +  T  +T 
Sbjct: 3233 TTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTP--ETVHTSTVLTTTTTTT 3290

Query: 1745 ALLPSTATESLAPSNTFVAPQPVVVAS 1771
                S AT S  P        P    +
Sbjct: 3291 RATGSVATPSSTPGTAHTTKVPTTTTT 3317



 Score =  131 bits (329), Expect = 8e-30
 Identities = 209/828 (25%), Positives = 309/828 (37%), Gaps = 133/828 (16%)

Query: 590  PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQV 649
            P+T   +S+ +  S P T  + T      T+ +S  +T+T        S T   A   +V
Sbjct: 4232 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTAT-------PSSTPGTAPPPKV 4284

Query: 650  VTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI 709
            +T              SP + P  ++  +          T PV TS  T   +T  VT I
Sbjct: 4285 LT--------------SPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATS-VTPI 4329

Query: 710  ----IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP--TILGISSVSPSTTKP 763
                + T G LP  T   + T +   P++   TT  S   T    T    SS S  ++ P
Sbjct: 4330 PSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTP 4389

Query: 764  GTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIAT 823
            GTT I+  +  +A  T   ATG T++P      T I T++ T+ T   +   TA P    
Sbjct: 4390 GTTWILTELTTAA--TTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS--- 4444

Query: 824  GHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883
                 G T ++ +  P    T+  TVP G     +    +A  P V+T          T 
Sbjct: 4445 --STPGTTWILTE--PSTTATV--TVPTGSTATASSTQATAGTPHVST--------TATT 4490

Query: 884  GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGG 943
             TVT + +T        S+S   AT +  L + AT +    + TAI  S+  TT T    
Sbjct: 4491 PTVTSSKATP-------SSSPGTATALPALRSTAT-TPTATSFTAIPSSSLGTTWTRLSQ 4542

Query: 944  LTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGD 1003
             TTPT TM            TA      + VH   V + A+ TT   T +V    S    
Sbjct: 4543 TTTPTATMS-----------TATPSSTPETVHTSTV-LTATATTTGATGSVATPSS---- 4586

Query: 1004 VQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
              PGT            H T    T TT   A     P       V     +  +  T+T
Sbjct: 4587 -TPGT-----------AHTTKVPTTTTTGFTATPSSSPGTALTPPV---WISTTTTPTTT 4631

Query: 1064 VGQQNGSVVRVCSNP-PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATT 1122
                +GS V   S P    T    TT T T AT +MA       P   T  +GT  + TT
Sbjct: 4632 TPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMA------TPSSSTQTSGTPPSLTT 4685

Query: 1123 AMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMA 1182
              +++ A        +   GT  +  +  +T    AA  SK+   +  +  T+TT+ V+ 
Sbjct: 4686 TATTITATGS-TTNPSSTPGTTPITPVLTSTATTPAATSSKA--TSSSSPRTATTLPVLT 4742

Query: 1183 TGAPCSAGPLLG--PSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAV--S 1238
            + A  S        PS         PA     P+S+   +S+      P   H+  V  +
Sbjct: 4743 STATKSTATSFTPIPSSTLWTTWTVPA-QTTTPMST---MSTIHTSSTPETTHTSTVLTT 4798

Query: 1239 TAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHE 1298
            TA MTR++                  +PS+T+  T +   L  +AT T            
Sbjct: 4799 TATMTRATNST--------------ATPSSTLGTTRILTELTTTATTT------------ 4832

Query: 1299 TGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCE 1358
              T +TAT S+      + + P         T +  TA+S  GT          A  P  
Sbjct: 4833 AATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTA 4892

Query: 1359 THQTTSTGTTMSVS-VGALLPDA--TSSHRTVESGLEVAAAPSVTPQA 1403
            T  T  + +T+  +   A+LP +  T S  TV S +     P+  P +
Sbjct: 4893 TASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSS 4940



 Score =  128 bits (322), Expect = 5e-29
 Identities = 257/1083 (23%), Positives = 380/1083 (35%), Gaps = 153/1083 (14%)

Query: 518  SLPAGVRMVVPTQSAQGTVIGSSPQMSGM--AALAAAAAATQKIPPSSAPTVLSVPAGTT 575
            S PA      P+ +   T I + P  +    A+  + A  T  +  +  P VL+  A T 
Sbjct: 1890 STPATSSTATPSSTPGTTWILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTP 1949

Query: 576  IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVS--SATNTSTRPII 633
             V +   TP ++   AT   A      +  AT +    ++ +GT+ +  S T T T  + 
Sbjct: 1950 TVTSSKATPSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMS 2009

Query: 634  TVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQ 693
            T   S T   A  + V+T      T T T     ++ P  +   ++  KV +   T    
Sbjct: 2010 TATPSSTPETAHTSTVLT-----ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTA 2064

Query: 694  T-SAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILG 752
            T S+  G A T PV  I  T  P   G+ +   +      T  + TT  +   T      
Sbjct: 2065 TPSSSPGTALTPPV-WISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATP 2123

Query: 753  ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPA 812
             SS   S T P  TT   TI          ATG T++P      T I   + T+ T   A
Sbjct: 2124 SSSTQTSGTPPSLTTTATTIT---------ATGSTTNPSSTPGTTPIPPVLTTTATTPAA 2174

Query: 813  KIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVT-- 870
               T  P  A G              P  P T+  T      R + P +   V+ A T  
Sbjct: 2175 TSNTVTPSSALG----------TTHTPPVPNTMATT----HGRSLPPSSPHTVRTAWTSA 2220

Query: 871  TLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAIT 930
            T  + GTT +T   TVT     +  G   HST A L++P  +  T  +  S        T
Sbjct: 2221 TSGILGTTHITEPSTVTSHTLAATTGTTQHSTPA-LSSPHPSSRTTESPPSPGTTTPGHT 2279

Query: 931  VSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPS-GVEAQPVHD--LPVSILASPTT 987
             + ++TT TA     T T T+ P S PT   + T  + G E Q      L  S      +
Sbjct: 2280 TATSRTTATATPS-KTRTSTLLP-SSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPS 2337

Query: 988  EQPTATVTIADSGQGDVQPGTVTLVC---SNPPCETHETGTTNTATTTVVANLGGHPQPT 1044
                 T +   +  G V    + L C   + P     E G     +              
Sbjct: 2338 GGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECS-------------L 2384

Query: 1045 QVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGC 1104
                VC  +E             N  +   C N     H   T  T++TA  +       
Sbjct: 2385 DFGLVCRNREQVGKFKMCF----NYEIRVFCCN---YGHCPSTPATSSTAMPS------- 2430

Query: 1105 SNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVI-------RISVATGALE 1157
            S P      T  T TATT  S+        A  +   GT  ++        ++V TG+  
Sbjct: 2431 STPGTTWILTELTTTATTTESTGST-----ATPSSTPGTTWILTEPSTTATVTVPTGSTA 2485

Query: 1158 AAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE-PGGRSPAFVQLAPLSS 1216
             A  +++   T   S T+TT TV ++     A P   P  A   P  RS A         
Sbjct: 2486 TASSTQATAGTPHVSTTATTPTVTSS----KATPFSSPGTATALPALRSTA--------- 2532

Query: 1217 KVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV---CESLQGGSPSTTVTVT 1273
                ++P+           A S  A+  SS+G    R++       ++   +PS+T    
Sbjct: 2533 ----TTPT-----------ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETV 2577

Query: 1274 ALEALLCPSATVTQVCSNPPCETHETGTTNTA---TTSNAGSAQRVCSNPPCETHETGTT 1330
                +L  +AT T    +    +   GT +T    TT+  G      S+P       GT 
Sbjct: 2578 HTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSP-------GTA 2630

Query: 1331 HTATTATSNGGTGQPEGGQQPPAGRPCETH-QTTSTGTTMSVSVGALLPDATSSHRTVES 1389
             T     S   T    G    P+  P  TH  T  T TT +V+ G++   AT S  T  S
Sbjct: 2631 RTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSM---ATPSSSTQTS 2687

Query: 1390 G---------LEVAAAPSVTPQAGTALLAPFP--------TQRVCSNPPCETHETGTTHT 1432
            G           + A  S T  + T    P P        T    S+    +   GTTHT
Sbjct: 2688 GTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHT 2747

Query: 1433 A----TTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVT 1488
                 TT T++  S     P         +T G ++  T  +  +T  S T      T  
Sbjct: 2748 PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSG-TLGTTHITEPSTGTSHTPAATTGTTQ 2806

Query: 1489 QSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVD 1548
             STP      P     +  P P    P      S +TA    S +  +++  P  P +  
Sbjct: 2807 HSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPS-KTRTSTLLPSSPTSAP 2865

Query: 1549 LSS 1551
            +++
Sbjct: 2866 ITT 2868



 Score =  122 bits (307), Expect = 3e-27
 Identities = 187/725 (25%), Positives = 271/725 (37%), Gaps = 80/725 (11%)

Query: 405  TAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVL 464
            TA+T ++ TP+  P   A PPK       +PA  P      +    ++ +P T TT+ VL
Sbjct: 4263 TASTGSTATPSSTPGT-APPPK----VLTSPATTP---TATSSKATSSSSPRTATTLPVL 4314

Query: 465  PTVPGSSISVPTAARTQGVPA-VLKVTG--PQATTGTPLVTMRPASQAGKAPVTVTSLPA 521
             +    S    TA     +P+  L  TG  P+ TT TP+ TM     +     T TS   
Sbjct: 4315 TSTATKS----TATSVTPIPSSTLGTTGTLPEQTT-TPVATMSTIHPSSTPETTHTSTVL 4369

Query: 522  GVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580
              +      ++  +   S+P  +  +  L  AA  T    P++ P+  S P  T I    
Sbjct: 4370 TTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPS--STPGTTWI---- 4423

Query: 581  AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGT 640
             +T  TTT   T    S+    S P T  + T  +   T      +T+T        S T
Sbjct: 4424 -LTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTAT-------ASST 4475

Query: 641  VTVAQQAQVVTTVVGGVTKTITLVK-SPISVPGGSALISNLGKVMSVVQTKPVQTS--AV 697
               A    V TT     T T+T  K +P S PG +  +  L        T P  TS  A+
Sbjct: 4476 QATAGTPHVSTT---ATTPTVTSSKATPSSSPGTATALPALRS----TATTPTATSFTAI 4528

Query: 698  TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVS 757
               +     T++ QT  P    T      +    P T+ T+T  +   T     G S  +
Sbjct: 4529 PSSSLGTTWTRLSQTTTP----TATMSTATPSSTPETVHTSTVLTATATTTGATG-SVAT 4583

Query: 758  PSTTKPGTTTIIK-----TIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSG-TGAP 811
            PS+T PGT    K     T   +A  + +  T +T    I +  T  TT   TSG T  P
Sbjct: 4584 PSST-PGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTP 4642

Query: 812  AKI--ITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAV 869
            + I   T   ++ T       T  V  G+   P +  +T         T  T++A     
Sbjct: 4643 SSIPGTTHTARVLT-----TTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTT 4697

Query: 870  TTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAI 929
                  GTT +T + T T T   + +     S+S   AT +  L + AT  S   + T I
Sbjct: 4698 NPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTAT-KSTATSFTPI 4756

Query: 930  TVSAAQTTLTAAGGLTTPTITMQPV---SQP---------TQVTLITAPSGVEAQPVHDL 977
              S   TT T     TTP  TM  +   S P         T    +T  +   A P   L
Sbjct: 4757 PSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTL 4816

Query: 978  PVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANL 1037
              + + +  T   T T     +      PGT  ++       T    T +TAT +  + L
Sbjct: 4817 GTTRILTELTTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATAS--STL 4874

Query: 1038 GGHPQPTQVQFVCDRQEAAASLV--TSTVGQQNGSVVRVCSNPPCETHETGTTNTATTAT 1095
            G    P  V  +     A AS V  +STVG      V   S P   T    T +++   T
Sbjct: 4875 GTAHTPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLP---TFSVSTVSSSVLTT 4931

Query: 1096 SNMAG 1100
                G
Sbjct: 4932 LRPTG 4936



 Score =  122 bits (306), Expect = 4e-27
 Identities = 333/1519 (21%), Positives = 508/1519 (33%), Gaps = 280/1519 (18%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            P+T AT+++ TP+  P       K P   A   A    T    + L + AP P   TT  
Sbjct: 1889 PSTPATSSTATPSSTPGTTWILTK-PTTTATTTASTGSTATPTSTL-RTAPPPKVLTTTA 1946

Query: 463  VLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAG 522
              PTV  S          +  P+          T T L  +R  +    A  +VT +P+ 
Sbjct: 1947 TTPTVTSS----------KATPS------SSPGTATALPALRSTATTPTA-TSVTPIPS- 1988

Query: 523  VRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT----IVK 578
                    S+ GT      Q +   A  + A  +     +   TVL+  A TT     V 
Sbjct: 1989 --------SSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVA 2040

Query: 579  TMAVTPG---TTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635
            T + TPG   TT +P T     +    S+P T +  T    + T+ +  T  S     TV
Sbjct: 2041 TPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL--TPPVWISTTTTPTTRGS-----TV 2093

Query: 636  HKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTS 695
              S        A V+TT       T T+    ++ P  S   S          T P  T+
Sbjct: 2094 TPSSIPGTTHTATVLTTT------TTTVATGSMATPSSSTQTSG---------TPPSLTT 2138

Query: 696  AVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISS 755
              T   +TG  T    T G  P   +  L T+A     T  T T +S  GT  T      
Sbjct: 2139 TATTITATGSTTNPSSTPGTTPIPPV--LTTTATTPAATSNTVTPSSALGTTHT------ 2190

Query: 756  VSPSTTKPGTTTIIKTIPMSAIIT-----QAGATGVTSSPGIKSPITIITTKVMTSGTGA 810
              P       TT  +++P S+  T      +  +G+  +  I  P T +T+  + + TG 
Sbjct: 2191 --PPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST-VTSHTLAATTGT 2247

Query: 811  PAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVT 870
                  + P +++ H     T+     +P  PGT   T P G     +  T +A      
Sbjct: 2248 TQH---STPALSSPHPSSRTTE-----SPPSPGT---TTP-GHTTATSRTTATATPSKTR 2295

Query: 871  TLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAIT 930
            T  +  ++  +   T   T+      A       S   P  + G   T S+      A+ 
Sbjct: 2296 TSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAV- 2354

Query: 931  VSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPV------HDLPVSILAS 984
                Q           P + ++ + Q  + +L         + V       +  + +   
Sbjct: 2355 --CEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCC 2412

Query: 985  PTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPT 1044
                 P+   T + +      PGT  ++          T  T TATTT        P  T
Sbjct: 2413 NYGHCPSTPAT-SSTAMPSSTPGTTWIL----------TELTTTATTTESTGSTATPSST 2461

Query: 1045 Q-VQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHG 1103
                ++       A++   T      S  +  +  P     T TT T T++ +      G
Sbjct: 2462 PGTTWILTEPSTTATVTVPTGSTATASSTQATAGTP-HVSTTATTPTVTSSKATPFSSPG 2520

Query: 1104 CSNPPCETHETGTTNTATT----AMSSVGANHQRDAR---------RACAAGTPAVIRIS 1150
             +        T TT TAT+      SS+G    R ++          A  + TP  +  S
Sbjct: 2521 TATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTS 2580

Query: 1151 ---VATGALEAAQGS-KSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSP 1206
                 T     A GS  +   T  T+ T+  +T   TG   +A P   P  AR      P
Sbjct: 2581 TVLTTTATTTGATGSVATPSSTPGTAHTTKVLTTTTTG--FTATPSSSPGTAR----TLP 2634

Query: 1207 AFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQ--GG 1264
             ++     +   R S+ +   +P   H+  V T   T  + G+    MA    S Q  G 
Sbjct: 2635 VWIS-TTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGS----MATPSSSTQTSGT 2689

Query: 1265 SPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCET 1324
             PS T T T + A    + + T   S P         T TATT  A S+    S+     
Sbjct: 2690 PPSLTTTATTITA----TGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSS----- 2740

Query: 1325 HETGTTHTA----TTATSNGGTGQPEGGQQPPAGRPCETHQTTST-GTTMSVSVGALLPD 1379
               GTTHT     TTAT++G +  P     P   R   T  T+ T GTT         P 
Sbjct: 2741 -ALGTTHTPPVPNTTATTHGRSLSP---SSPHTVRTAWTSATSGTLGTTHITE-----PS 2791

Query: 1380 ATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPP-----CETHETGTTHTAT 1434
              +SH         AA    T  +  AL +P P+ R   +PP        H   T+ T  
Sbjct: 2792 TGTSHTP-------AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTA 2844

Query: 1435 TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT---TVTQST 1491
            T T + +      P++                 +S+ ITT V+            +  S 
Sbjct: 2845 TATPSKTRTSTLLPSS----------------PTSAPITTVVTMGCEPQCAWSEWLDYSY 2888

Query: 1492 PVPGPS-----------------VPPPEELQVSPGPRQQLPPRQLLQSASTAL------- 1527
            P+PGPS                    P  L+     +  +P R+L Q    +L       
Sbjct: 2889 PMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCR 2948

Query: 1528 ----MGE--------------------SAEVLSASQTP------------ELPAAVDLSS 1551
                +G+                    S    S++ TP            +  AA   ++
Sbjct: 2949 NREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTAT 3008

Query: 1552 TGE---PSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE------LMAEAQAGTT-- 1600
            TG    PSS   +A    V T     P  T S+    S P+       L + A   T   
Sbjct: 3009 TGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATS 3068

Query: 1601 -------TLMVTGLTPEELAVTAAAEAAAQAAATEE----AQALAIQAVLQAAQQAVMGT 1649
                   TL  TG  PE+     A  +    ++T E    +  L  +A    A  ++   
Sbjct: 3069 FTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTP 3128

Query: 1650 GEPMDTSEAAATVTQAELGHLSAEGQEGQATTIP---IVLTQQELAALVQQQQLQEAQAQ 1706
                 T+     +T A     +A G     ++ P    +LT+    A V       A A 
Sbjct: 3129 SSTPGTTWILTELTTAAT-TTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS 3187

Query: 1707 QQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQP 1766
                   T  +  + +     I S        + P T   LP+  + +  P+ T V   P
Sbjct: 3188 STRATAGTLKVLTSTATTPTVISSRA---TPSSSPGTATALPALRSTATTPTATSVTAIP 3244

Query: 1767 VVVASPAKLQAAATLTEVA 1785
                  A  + + T T  A
Sbjct: 3245 SSSLGTAWTRLSQTTTPTA 3263



 Score =  115 bits (289), Expect = 3e-25
 Identities = 177/695 (25%), Positives = 262/695 (37%), Gaps = 72/695 (10%)

Query: 366  PPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPAN-- 423
            PP +V    A T +   S    +++      L      AT +TATS TP P  ++     
Sbjct: 4280 PPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4339

Query: 424  -PPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQG 482
             P ++  P A    + P            +  P TT T  VL T   ++ +  + +    
Sbjct: 4340 LPEQTTTPVATMSTIHP------------SSTPETTHTSTVLTTKATTTRATSSTSTPSS 4387

Query: 483  VPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQ 542
             P    +     T  T      P +     P T   L         T S   T   SS  
Sbjct: 4388 TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTP 4447

Query: 543  MSGMAALAAAAAATQKIPPSSAPTVLS--VPAGTTIVKTMAVTPGTTTLPATVKVASSP- 599
             +       +  AT  +P  S  T  S    AGT  V T A TP  T+  AT   +SSP 
Sbjct: 4448 GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT--PSSSPG 4505

Query: 600  VMVSNPATRMLKTAAAQVGTSV-----SSATNTSTRPIITVHKSGTVTVAQQAQ----VV 650
               + PA R   TA     TS      SS   T TR   T   + T++ A  +     V 
Sbjct: 4506 TATALPALR--STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVH 4563

Query: 651  TTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQT-SAVTGQASTGPV--- 706
            T+ V   T T T     ++ P  +   ++  KV +   T    T S+  G A T PV   
Sbjct: 4564 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIS 4623

Query: 707  -TQIIQTKGPLPAGTILKLV----TSADGKPTTIITTTQASGAGTKPTILGISSVSPSTT 761
             T    T  P  +G+ +       T+   +  T  TTT A+G+   P+    SS   S T
Sbjct: 4624 TTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPS----SSTQTSGT 4679

Query: 762  KPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKI 821
             P  TT   TI          ATG T++P   +P T   T V+TS    PA       K 
Sbjct: 4680 PPSLTTTATTIT---------ATGSTTNPS-STPGTTPITPVLTSTATTPA---ATSSKA 4726

Query: 822  ATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVT 881
             +    +  T + +  +     T     P+    L T  TV    PA TT  +   + + 
Sbjct: 4727 TSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTV----PAQTTTPMSTMSTIH 4782

Query: 882  TLGTVTGTVSTSLAGAGGHSTSA--SLATPITTLGTIATLSSQVINPTAITVSAAQTTLT 939
            T  T   T ++++       T A  S ATP +TLGT   L+   +  TA T +A  +T T
Sbjct: 4783 TSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTE--LTTTATTTAATGSTAT 4840

Query: 940  AAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTT---EQPTATVTI 996
             +   +TP  T   +++P+ +  +  P+G  A     L  +      T     PTAT + 
Sbjct: 4841 LS---STPGTTW-ILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATAST 4896

Query: 997  ADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
              S        T  ++ S+ P  +  T +++  TT
Sbjct: 4897 VPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTT 4931



 Score = 82.0 bits (201), Expect = 5e-15
 Identities = 101/399 (25%), Positives = 164/399 (41%), Gaps = 41/399 (10%)

Query: 365  PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANP 424
            P       V   T +   + G+VAT  S         +P T  T  + TP+  P     P
Sbjct: 4559 PETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTP 4618

Query: 425  PKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT-----VPGSSISVPTAAR 479
            P   +         P T  G T+ P + P   TT T +VL T       GS  +  ++ +
Sbjct: 4619 PVWISTTTTPTTTTPTTS-GSTVTPSSIPG--TTHTARVLTTTTTTVATGSMATPSSSTQ 4675

Query: 480  TQGVPAVLKVTGPQAT-TGTPLVTMRPASQAGKAPVT-----VTSLPAGVRMVVPTQSAQ 533
            T G P  L  T    T TG+   T  P+S  G  P+T       + PA       + S+ 
Sbjct: 4676 TSGTPPSLTTTATTITATGS---TTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSP 4732

Query: 534  GTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATV 593
             T   + P ++  A  + A + T  IP S+  T  +VPA TT   +   T  T++ P T 
Sbjct: 4733 RTAT-TLPVLTSTATKSTATSFT-PIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPETT 4790

Query: 594  KVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV 653
              ++   +++  AT    T +    T+  S+T  +TR +  +  + T T A  +    + 
Sbjct: 4791 HTST---VLTTTATMTRATNS----TATPSSTLGTTRILTELTTTATTTAATGSTATLSS 4843

Query: 654  VGGVTKTIT--LVKSPISVPGGSALI--SNLG-----KVMSVVQTKPVQTSAVTGQASTG 704
              G T  +T     + + VP GS     S LG     KV++ + T P  T++    +ST 
Sbjct: 4844 TPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTV 4903

Query: 705  PVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASG 743
              T   +T   LP+      V++     ++++TT + +G
Sbjct: 4904 GTT---RTPAVLPSSLPTFSVSTVS---SSVLTTLRPTG 4936



 Score = 81.3 bits (199), Expect = 9e-15
 Identities = 125/543 (23%), Positives = 197/543 (36%), Gaps = 115/543 (21%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            + T ++ V  G+ ATA S          P  + TAT+PT   V S  A P  SP  A A 
Sbjct: 4457 STTATVTVPTGSTATASSTQATA---GTPHVSTTATTPT---VTSSKATPSSSPGTATAL 4510

Query: 435  PAVQ--------------PLTQVGITLLPQAAPAPPTTTTIQVLP--------------- 465
            PA++              P + +G T    +    PT T     P               
Sbjct: 4511 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTA 4570

Query: 466  --TVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKA----------- 512
              T  G++ SV T + T G     KV     TT T   T  P+S  G A           
Sbjct: 4571 TATTTGATGSVATPSSTPGTAHTTKVP----TTTTTGFTATPSSSPGTALTPPVWISTTT 4626

Query: 513  -PVTVTSLPAGVRMV---VP--TQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566
             P T T   +G  +    +P  T +A+     ++   +G  A  +++  T   PPS   T
Sbjct: 4627 TPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTT 4686

Query: 567  VLSVPAGTTIVKTMAVTPGTTTL-PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
              ++ A T      + TPGTT + P     A++P   S+ AT       A     ++S  
Sbjct: 4687 ATTITA-TGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTA 4745

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
              ST    T   S T+         TT       TI    +P +        ++   V++
Sbjct: 4746 TKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTSSTPET--------THTSTVLT 4797

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAG 745
               T    T++    +ST   T+I+                    + TT  TTT A+G  
Sbjct: 4798 TTATMTRATNSTATPSSTLGTTRILT-------------------ELTTTATTTAATG-- 4836

Query: 746  TKPTILGISSVSPSTTKPGTTTII-KTIPMSAIITQAGATGVTSSPGIKSPITIITTKVM 804
                     S +  ++ PGTT I+ +   ++ ++   G+T   SS    +  T  T KV+
Sbjct: 4837 ---------STATLSSTPGTTWILTEPSTIATVMVPTGSTATASS----TLGTAHTPKVV 4883

Query: 805  TSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSA 864
            T+    P    + VP  +T             G    P  +  ++P   V  V+   ++ 
Sbjct: 4884 TTMATMPTATASTVPSSST------------VGTTRTPAVLPSSLPTFSVSTVSSSVLTT 4931

Query: 865  VKP 867
            ++P
Sbjct: 4932 LRP 4934


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score =  161 bits (408), Expect = 5e-39
 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620
            GS    T        T S     +   E    + AG  TTT   +G        T +  +
Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
               +A +E   A  I +    A  A +   EP  TS   +  T      ++A G    +T
Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278

Query: 1681 TI 1682
            T+
Sbjct: 1279 TV 1280



 Score =  154 bits (389), Expect = 8e-37
 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             +  T +S+ GA    D+       AA T      +V+T   E    S +  +T   S T
Sbjct: 560  GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
             +  T  +T                                     SS +      G  +
Sbjct: 620  GSETTTAST------------------------------------TSSETTTASTEGSET 643

Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293
              VST     + V   G  R     E    GS +TTV+ T  E  +    + T   S   
Sbjct: 644  TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699

Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351
             ET +  TT   T TTS  GS     S    ET    T  + TT  S  G+   E     
Sbjct: 700  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756

Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384
              G    T  TTS+ TTM+  +G+                              + T + 
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             T      V+ A S T  A T   A   T    S    ET    T  + TT  S  SS  
Sbjct: 817  TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                    +    ST+G     TS+    TT +ST    +TTV+ +      +     E 
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564
              +     +L       S +  +  E +E  + + T         S+ G  ++   +AGS
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623
                  +      T S     S   E    +  GT TT+  T  +      TA +E  A 
Sbjct: 992  ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046

Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679
                 E    + +    +    V  TG    T+  A     TV+ +  G  +A     + 
Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732
            TT+ I         T+   A  V     +   A      + T     +++     I S  
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
              +  AG+  +T +   S T T S A S T  A       + A    + T T    G E+
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223



 Score =  146 bits (369), Expect = 2e-34
 Identities = 260/1174 (22%), Positives = 425/1174 (36%), Gaps = 149/1174 (12%)

Query: 451  AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
            A+   P TT +      + TV  +      A+        +  TG + TT + + +    
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566
                 +  T  S          T+ ++ T + ++   +   ++  +   T     S    
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 567  VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619
            V +    TT   T        + +   TT  +T    ++ V  +   T+   T  ++  T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483

Query: 620  SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679
            + +S T   T  + T+    T    + ++  TT V      +T V +  S    +  +S 
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538

Query: 680  LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727
             G   + V T  ++T       S +T  ++TG  T    T+G        AG+    V++
Sbjct: 539  TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598

Query: 728  ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780
            AD + TT  T    TT AS  G++ T    +S    + ST    TTT+  T   + +++ 
Sbjct: 599  ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658

Query: 781  AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834
             G+   +TS+ G ++     T   T V T G+G     IT     K++T   +   T   
Sbjct: 659  TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717

Query: 835  LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892
                    G+ + T  + G    T  T  +     TT   +G  TT  +T G+ T T ST
Sbjct: 718  -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767

Query: 893  SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940
            + +     S   S  T  +T+G+    ++T SS++            A T ++  TT++ 
Sbjct: 768  TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827

Query: 941  AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
            AG  T P  T       ++ T  T+  G E             + T    T T T     
Sbjct: 828  AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879

Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060
                  G+ T   S    ET  T T  + TTT  A+  G    T      +   A+    
Sbjct: 880  ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931

Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109
             +T     GS +   S    ET        ET T  T  + T T++ AG      S    
Sbjct: 932  ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160
            ET       + TT +SS G+    +       GT   I          ++ A     A  
Sbjct: 992  ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047

Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217
             + S+  T  T  + TT TV  TG+     S   L   +++    G + A    +  ++ 
Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277
                S +      G  +  VST +   ++       M  V  ++   +  +T+   A  +
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166

Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337
                S   T         T  T  + T T S AGS     S    ET+   TT + T+  
Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226

Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392
            S+ G+               ET+     G+ T   S  +L P AT    S   TV     
Sbjct: 1227 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440
             A A S T  + T +L        Q + + P   T  TGT  TA++          T++ 
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            +S+  P    +  G   ST G S + TS+  + TT  ST     +T  ++    GP    
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534
               + +S  P   + P   LQ  +  L+  +A V
Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420



 Score =  140 bits (353), Expect = 1e-32
 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +   TT T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  124 bits (312), Expect = 7e-28
 Identities = 214/959 (22%), Positives = 336/959 (35%), Gaps = 105/959 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            +A  K TT+ T    TT AS   ++ T +   G  ++  ST    TTT   T        
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 780  QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836
                +  T++    S  T  TT   +  T+ T       T+     T       +++   
Sbjct: 857  STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 837  GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890
               G   T   T         T      TVS       T+  +G  TT VTT+G+ T T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976

Query: 891  STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945
            ST    AG  +T+ S A   TT  +I      T+SS     T ++ +  +TT+T+  G  
Sbjct: 977  ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032

Query: 946  TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002
            T T+T          T  +  +    +      VS   S TT   TA   T T++ SG G
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
                             G+ T   S    E     TT++ TTT  A+  G    T    V
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108
             +    +     +T     GS     S    ET    T  + TT  S    +    S   
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168
             ET+   TT + T+  SS G+    +   A   G+   I    +T +LE    S +  +T
Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1263

Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215
               S T           S+T  V+      S  P+    M+  R  G R  A       S
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1316

Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269
            S V + +P + D  A   SH V     +T+ +  S++GA     A    +  G +   T
Sbjct: 1317 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%)

Query: 446  TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505
            T   + + A   +TT     T   +   + T   T      +   G +ATT +   +   
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 506  ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565
             +    +  T  S          T  ++ T   +S   +  A    +  +T     S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T   + + TTI  T ++ P  T+L  +    ++ V ++        T  +     ++ AT
Sbjct: 1235 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1291

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684
            + S +PI     SGT T   +    ++V        T   +  +VPG     S LG   M
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351

Query: 685  SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736
                T        T  ++  P +   Q  GP+  GT      S    PT +I
Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1400



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score =  161 bits (408), Expect = 5e-39
 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620
            GS    T        T S     +   E    + AG  TTT   +G        T +  +
Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
               +A +E   A  I +    A  A +   EP  TS   +  T      ++A G    +T
Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278

Query: 1681 TI 1682
            T+
Sbjct: 1279 TV 1280



 Score =  154 bits (389), Expect = 8e-37
 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             +  T +S+ GA    D+       AA T      +V+T   E    S +  +T   S T
Sbjct: 560  GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
             +  T  +T                                     SS +      G  +
Sbjct: 620  GSETTTAST------------------------------------TSSETTTASTEGSET 643

Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293
              VST     + V   G  R     E    GS +TTV+ T  E  +    + T   S   
Sbjct: 644  TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699

Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351
             ET +  TT   T TTS  GS     S    ET    T  + TT  S  G+   E     
Sbjct: 700  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756

Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384
              G    T  TTS+ TTM+  +G+                              + T + 
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             T      V+ A S T  A T   A   T    S    ET    T  + TT  S  SS  
Sbjct: 817  TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                    +    ST+G     TS+    TT +ST    +TTV+ +      +     E 
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564
              +     +L       S +  +  E +E  + + T         S+ G  ++   +AGS
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623
                  +      T S     S   E    +  GT TT+  T  +      TA +E  A 
Sbjct: 992  ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046

Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679
                 E    + +    +    V  TG    T+  A     TV+ +  G  +A     + 
Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732
            TT+ I         T+   A  V     +   A      + T     +++     I S  
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
              +  AG+  +T +   S T T S A S T  A       + A    + T T    G E+
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223



 Score =  147 bits (370), Expect = 1e-34
 Identities = 260/1174 (22%), Positives = 425/1174 (36%), Gaps = 149/1174 (12%)

Query: 451  AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
            A+   P TT +      + TV  +      A+        +  TG + TT + + +    
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566
                 +  T  S          T+ ++ T + ++   +   ++  +   T     S    
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 567  VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619
            V +    TT   T        + +   TT  +T    ++ V  +   T+   T  ++  T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483

Query: 620  SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679
            + +S T   T  + T+    T    + ++  TT V      +T V +  S    +  +S 
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538

Query: 680  LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727
             G   + V T  ++T       S +T  ++TG  T    T+G        AG+    V++
Sbjct: 539  TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598

Query: 728  ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780
            AD + TT  T    TT AS  G++ T    +S    + ST    TTT+  T   + +++ 
Sbjct: 599  ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658

Query: 781  AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834
             G+   +TS+ G ++     T   T V T G+G     IT     K++T   +   T   
Sbjct: 659  TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717

Query: 835  LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892
                    G+ + T  + G    T  T  +     TT   +G  TT  +T G+ T T ST
Sbjct: 718  -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767

Query: 893  SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940
            + +     S   S  T  +T+G+    ++T SS++            A T ++  TT++ 
Sbjct: 768  TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827

Query: 941  AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
            AG  T P  T       ++ T  T+  G E             + T    T T T     
Sbjct: 828  AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879

Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060
                  G+ T   S    ET  T T  + TTT  A+  G    T      +   A+    
Sbjct: 880  ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931

Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109
             +T     GS +   S    ET        ET T  T  + T T++ AG      S    
Sbjct: 932  ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160
            ET       + TT +SS G+    +       GT   I          ++ A     A  
Sbjct: 992  ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047

Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217
             + S+  T  T  + TT TV  TG+     S   L   +++    G + A    +  ++ 
Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277
                S +      G  +  VST +   ++       M  V  ++   +  +T+   A  +
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166

Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337
                S   T         T  T  + T T S AGS     S    ET+   TT + T+  
Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226

Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392
            S+ G+               ET+     G+ T   S  +L P AT    S   TV     
Sbjct: 1227 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440
             A A S T  + T +L        Q + + P   T  TGT  TA++          T++ 
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASA 1331

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            +S+  P    +  G   ST G S + TS+  + TT  ST     +T  ++    GP    
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534
               + +S  P   + P   LQ  +  L+  +A V
Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420



 Score =  140 bits (353), Expect = 1e-32
 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +   TT T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  125 bits (313), Expect = 5e-28
 Identities = 212/959 (22%), Positives = 334/959 (34%), Gaps = 105/959 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            +A  K TT+ T    TT AS   ++ T +   G  ++  ST    TTT   T        
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 780  QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836
                +  T++    S  T  TT   +  T+ T       T+     T       +++   
Sbjct: 857  STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 837  GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890
               G   T   T         T      TVS       T+  +G  TT VTT+G+ T T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976

Query: 891  STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945
            ST    AG  +T+ S A   TT  +I      T+SS     T ++ +  +TT+T+  G  
Sbjct: 977  ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032

Query: 946  TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002
            T T+T          T  +  +    +      VS   S TT   TA   T T++ SG G
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
                             G+ T   S    E     TT++ TTT  A+  G    T    V
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108
             +    +     +T     GS     S    ET    T  + TT  S    +    S   
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168
             ET+   TT + T+  SS G+    +   A   G+   I    +T +LE    S +  +T
Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1263

Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215
               S T           S+T  V+      S  P+    M+  R  G R        P +
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTR--------PTA 1315

Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269
            S     +P + D  A   SH V     +T+ +  S++GA     A    +  G +   T
Sbjct: 1316 SSSVTMAPGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%)

Query: 446  TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505
            T   + + A   +TT     T   +   + T   T      +   G +ATT +   +   
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 506  ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565
             +    +  T  S          T  ++ T   +S   +  A    +  +T     S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T   + + TTI  T ++ P  T+L  +    ++ V ++        T  +     ++ AT
Sbjct: 1235 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1291

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684
            + S +PI     SGT T   +    ++V        T   +  +VPG     S LG   M
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351

Query: 685  SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736
                T        T  ++  P +   Q  GP+  GT      S    PT +I
Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1400



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score =  161 bits (408), Expect = 5e-39
 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620
            GS    T        T S     +   E    + AG  TTT   +G        T +  +
Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
               +A +E   A  I +    A  A +   EP  TS   +  T      ++A G    +T
Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278

Query: 1681 TI 1682
            T+
Sbjct: 1279 TV 1280



 Score =  154 bits (389), Expect = 8e-37
 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             +  T +S+ GA    D+       AA T      +V+T   E    S +  +T   S T
Sbjct: 560  GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
             +  T  +T                                     SS +      G  +
Sbjct: 620  GSETTTAST------------------------------------TSSETTTASTEGSET 643

Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293
              VST     + V   G  R     E    GS +TTV+ T  E  +    + T   S   
Sbjct: 644  TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699

Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351
             ET +  TT   T TTS  GS     S    ET    T  + TT  S  G+   E     
Sbjct: 700  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756

Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384
              G    T  TTS+ TTM+  +G+                              + T + 
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             T      V+ A S T  A T   A   T    S    ET    T  + TT  S  SS  
Sbjct: 817  TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                    +    ST+G     TS+    TT +ST    +TTV+ +      +     E 
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564
              +     +L       S +  +  E +E  + + T         S+ G  ++   +AGS
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623
                  +      T S     S   E    +  GT TT+  T  +      TA +E  A 
Sbjct: 992  ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046

Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679
                 E    + +    +    V  TG    T+  A     TV+ +  G  +A     + 
Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732
            TT+ I         T+   A  V     +   A      + T     +++     I S  
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
              +  AG+  +T +   S T T S A S T  A       + A    + T T    G E+
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223



 Score =  147 bits (370), Expect = 1e-34
 Identities = 260/1174 (22%), Positives = 425/1174 (36%), Gaps = 149/1174 (12%)

Query: 451  AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
            A+   P TT +      + TV  +      A+        +  TG + TT + + +    
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566
                 +  T  S          T+ ++ T + ++   +   ++  +   T     S    
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 567  VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619
            V +    TT   T        + +   TT  +T    ++ V  +   T+   T  ++  T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483

Query: 620  SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679
            + +S T   T  + T+    T    + ++  TT V      +T V +  S    +  +S 
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538

Query: 680  LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727
             G   + V T  ++T       S +T  ++TG  T    T+G        AG+    V++
Sbjct: 539  TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598

Query: 728  ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780
            AD + TT  T    TT AS  G++ T    +S    + ST    TTT+  T   + +++ 
Sbjct: 599  ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658

Query: 781  AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834
             G+   +TS+ G ++     T   T V T G+G     IT     K++T   +   T   
Sbjct: 659  TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717

Query: 835  LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892
                    G+ + T  + G    T  T  +     TT   +G  TT  +T G+ T T ST
Sbjct: 718  -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767

Query: 893  SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940
            + +     S   S  T  +T+G+    ++T SS++            A T ++  TT++ 
Sbjct: 768  TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827

Query: 941  AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
            AG  T P  T       ++ T  T+  G E             + T    T T T     
Sbjct: 828  AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879

Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060
                  G+ T   S    ET  T T  + TTT  A+  G    T      +   A+    
Sbjct: 880  ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931

Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109
             +T     GS +   S    ET        ET T  T  + T T++ AG      S    
Sbjct: 932  ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160
            ET       + TT +SS G+    +       GT   I          ++ A     A  
Sbjct: 992  ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047

Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217
             + S+  T  T  + TT TV  TG+     S   L   +++    G + A    +  ++ 
Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277
                S +      G  +  VST +   ++       M  V  ++   +  +T+   A  +
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166

Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337
                S   T         T  T  + T T S AGS     S    ET+   TT + T+  
Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226

Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392
            S+ G+               ET+     G+ T   S  +L P AT    S   TV     
Sbjct: 1227 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440
             A A S T  + T +L        Q + + P   T  TGT  TA++          T++ 
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASA 1331

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            +S+  P    +  G   ST G S + TS+  + TT  ST     +T  ++    GP    
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534
               + +S  P   + P   LQ  +  L+  +A V
Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420



 Score =  140 bits (353), Expect = 1e-32
 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +   TT T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  125 bits (313), Expect = 5e-28
 Identities = 212/959 (22%), Positives = 334/959 (34%), Gaps = 105/959 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            +A  K TT+ T    TT AS   ++ T +   G  ++  ST    TTT   T        
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 780  QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836
                +  T++    S  T  TT   +  T+ T       T+     T       +++   
Sbjct: 857  STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 837  GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890
               G   T   T         T      TVS       T+  +G  TT VTT+G+ T T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976

Query: 891  STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945
            ST    AG  +T+ S A   TT  +I      T+SS     T ++ +  +TT+T+  G  
Sbjct: 977  ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032

Query: 946  TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002
            T T+T          T  +  +    +      VS   S TT   TA   T T++ SG G
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
                             G+ T   S    E     TT++ TTT  A+  G    T    V
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108
             +    +     +T     GS     S    ET    T  + TT  S    +    S   
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168
             ET+   TT + T+  SS G+    +   A   G+   I    +T +LE    S +  +T
Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1263

Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215
               S T           S+T  V+      S  P+    M+  R  G R        P +
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTR--------PTA 1315

Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269
            S     +P + D  A   SH V     +T+ +  S++GA     A    +  G +   T
Sbjct: 1316 SSSVTMAPGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%)

Query: 446  TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505
            T   + + A   +TT     T   +   + T   T      +   G +ATT +   +   
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 506  ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565
             +    +  T  S          T  ++ T   +S   +  A    +  +T     S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T   + + TTI  T ++ P  T+L  +    ++ V ++        T  +     ++ AT
Sbjct: 1235 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1291

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684
            + S +PI     SGT T   +    ++V        T   +  +VPG     S LG   M
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351

Query: 685  SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736
                T        T  ++  P +   Q  GP+  GT      S    PT +I
Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1400



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score =  161 bits (407), Expect = 7e-39
 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620
            GS    T        T S     +   E    + AG  TTT   +G        T +  +
Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
               +A +E   A  I +    A  A +   EP  TS   +  T      ++A G    +T
Sbjct: 1225 TPSSAGSETNTAFIIGSESTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278

Query: 1681 TI 1682
            T+
Sbjct: 1279 TV 1280



 Score =  154 bits (389), Expect = 8e-37
 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             +  T +S+ GA    D+       AA T      +V+T   E    S +  +T   S T
Sbjct: 560  GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
             +  T  +T                                     SS +      G  +
Sbjct: 620  GSETTTAST------------------------------------TSSETTTASTEGSET 643

Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293
              VST     + V   G  R     E    GS +TTV+ T  E  +    + T   S   
Sbjct: 644  TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699

Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351
             ET +  TT   T TTS  GS     S    ET    T  + TT  S  G+   E     
Sbjct: 700  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756

Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384
              G    T  TTS+ TTM+  +G+                              + T + 
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             T      V+ A S T  A T   A   T    S    ET    T  + TT  S  SS  
Sbjct: 817  TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                    +    ST+G     TS+    TT +ST    +TTV+ +      +     E 
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564
              +     +L       S +  +  E +E  + + T         S+ G  ++   +AGS
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623
                  +      T S     S   E    +  GT TT+  T  +      TA +E  A 
Sbjct: 992  ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046

Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679
                 E    + +    +    V  TG    T+  A     TV+ +  G  +A     + 
Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732
            TT+ I         T+   A  V     +   A      + T     +++     I S  
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
              +  AG+  +T +   S T T S A S T  A       + A    + T T    G E+
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223



 Score =  146 bits (369), Expect = 2e-34
 Identities = 259/1174 (22%), Positives = 426/1174 (36%), Gaps = 149/1174 (12%)

Query: 451  AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
            A+   P TT +      + TV  +      A+        +  TG + TT + + +    
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566
                 +  T  S          T+ ++ T + ++   +   ++  +   T     S    
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 567  VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619
            V +    TT   T        + +   TT  +T    ++ V  +   T+   T  ++  T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483

Query: 620  SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679
            + +S T   T  + T+    T    + ++  TT V      +T V +  S    +  +S 
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538

Query: 680  LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727
             G   + V T  ++T       S +T  ++TG  T    T+G        AG+    V++
Sbjct: 539  TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598

Query: 728  ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780
            AD + TT  T    TT AS  G++ T    +S    + ST    TTT+  T   + +++ 
Sbjct: 599  ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658

Query: 781  AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834
             G+   +TS+ G ++     T   T V T G+G     IT     K++T   +   T   
Sbjct: 659  TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717

Query: 835  LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892
                    G+ + T  + G    T  T  +     TT   +G  TT  +T G+ T T ST
Sbjct: 718  -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767

Query: 893  SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940
            + +     S   S  T  +T+G+    ++T SS++            A T ++  TT++ 
Sbjct: 768  TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827

Query: 941  AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
            AG  T P  T       ++ T  T+  G E             + T    T T T     
Sbjct: 828  AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879

Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060
                  G+ T   S    ET  T T  + TTT  A+  G    T      +   A+    
Sbjct: 880  ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931

Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109
             +T     GS +   S    ET        ET T  T  + T T++ AG      S    
Sbjct: 932  ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160
            ET       + TT +SS G+    +       GT   I          ++ A     A  
Sbjct: 992  ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047

Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217
             + S+  T  T  + TT TV  TG+     S   L   +++    G + A    +  ++ 
Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277
                S +      G  +  VST +   ++       M  V  ++   +  +T+   A  +
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166

Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337
                S   T         T  T  + T T S AGS     S    ET+   TT + T+  
Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226

Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSV-SVGALLPDAT----SSHRTVESGLE 1392
            S+ G+               ET+     G+  ++ S  +L P AT    S   TV     
Sbjct: 1227 SSAGS---------------ETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440
             A A S T  + T +L        Q + + P   T  TGT  TA++          T++ 
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            +S+  P    +  G   ST G S + TS+  + TT  ST     +T  ++    GP    
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534
               + +S  P   + P   LQ  +  L+  +A V
Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420



 Score =  140 bits (353), Expect = 1e-32
 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +   TT T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  125 bits (313), Expect = 5e-28
 Identities = 214/959 (22%), Positives = 337/959 (35%), Gaps = 105/959 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            +A  K TT+ T    TT AS   ++ T +   G  ++  ST    TTT   T        
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 780  QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836
                +  T++    S  T  TT   +  T+ T       T+     T       +++   
Sbjct: 857  STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 837  GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890
               G   T   T         T      TVS       T+  +G  TT VTT+G+ T T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976

Query: 891  STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945
            ST    AG  +T+ S A   TT  +I      T+SS     T ++ +  +TT+T+  G  
Sbjct: 977  ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032

Query: 946  TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002
            T T+T          T  +  +    +      VS   S TT   TA   T T++ SG G
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
                             G+ T   S    E     TT++ TTT  A+  G    T    V
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108
             +    +     +T     GS     S    ET    T  + TT  S    +    S   
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168
             ET+   TT + T+  SS G+    +   A   G+ + I    +T +LE    S +  +T
Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSESTI---ASTASLEPTATSLTGSET 1263

Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215
               S T           S+T  V+      S  P+    M+  R  G R  A       S
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1316

Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269
            S V + +P + D  A   SH V     +T+ +  S++GA     A    +  G +   T
Sbjct: 1317 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score =  161 bits (407), Expect = 7e-39
 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 60   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTIS 119

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 120  TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 179

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 180  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 236

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 237  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 294

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 295  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 347

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 348  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 397

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 398  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 457

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 458  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 512

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 513  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 572

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 573  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 627

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 628  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 680

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 681  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 735

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 736  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 785

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 786  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 839

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 840  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 893

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 894  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 953

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 954  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 1013

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 1014 TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1072

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1073 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1132

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1133 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1190

Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620
            GS    T        T S     +   E    + AG  TTT   +G        T +  +
Sbjct: 1191 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1245

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
               +A +E   A  I +    A  A +   EP  TS   +  T      ++A G    +T
Sbjct: 1246 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1299

Query: 1681 TI 1682
            T+
Sbjct: 1300 TV 1301



 Score =  157 bits (398), Expect = 8e-38
 Identities = 294/1334 (22%), Positives = 451/1334 (33%), Gaps = 170/1334 (12%)

Query: 529  TQSAQGTVIGSSPQMSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AV 582
            T +A   VI +S  MS    +A AA +   T     S   T+L   + TT   T      
Sbjct: 9    TSTADSKVITAS-SMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETT 67

Query: 583  TPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVT 642
            TP  T    T+   S   + +        T  +  G+  ++A+   +   I+   S T T
Sbjct: 68   TPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTISTAGSETTT 127

Query: 643  VAQQAQVVTTV--VGGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA 696
            V+      T V  +G  T T +   S  +V       +  +S +G   +   T   +T+A
Sbjct: 128  VSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTA 187

Query: 697  --VTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGIS 754
               TG   T   T   +T  P  AG+    V++A  + TT+ TT    G+ T       S
Sbjct: 188  ASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHS 243

Query: 755  SVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKI 814
              + ++T    TT + T      ++ AG+    +S       T  T    T+        
Sbjct: 244  ETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFE 303

Query: 815  ITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVV 874
             TA     TG      ++  +    G   T+  T+     +      VS     VTT+  
Sbjct: 304  TTAAS--TTG------SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFA 349

Query: 875  KG--TTGVTTLGTVTGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPT 927
             G  T   +T+G+ T TVST+    G  +T+AS+     +T  TT     T S++    T
Sbjct: 350  AGSETIRASTVGSETTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETT 405

Query: 928  AITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTT 987
              +   ++ T  +  G  T T+++      T  T        E   +  +  ++  + T 
Sbjct: 406  TASTEGSEATTVSTTGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTA 457

Query: 988  EQPTATVTIADSGQGDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQP 1043
                + +TIA +   +       G+ T   +    ET    TT + TTT  A+  G    
Sbjct: 458  STEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETT 515

Query: 1044 TQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHG 1103
            T      D   A+     +T     GS +   S    E     TT + TT  S       
Sbjct: 516  TVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---- 571

Query: 1104 CSNPPCETHETGTTNTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQ 1160
                  ET  T T  +  T +S+ GA    D+       AA T      +V+T   E   
Sbjct: 572  -----LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTT 626

Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRL 1220
             S +  +T   S T +  T  +T                                     
Sbjct: 627  ASTADSETTSASTTGSETTTAST------------------------------------T 650

Query: 1221 SSPSIKDLPAGRHSHAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALL 1279
            SS +      G  +  VST     + V   G  R     E    GS +TTV+ T  E  +
Sbjct: 651  SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTV 706

Query: 1280 CPSATVTQVCSNPPCETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337
                + T   S    ET +  TT   T TTS  GS     S    ET    T  + TT  
Sbjct: 707  STEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTA 766

Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALL-------------------- 1377
            S  G+   E       G    T  TTS+ TTM+  +G+                      
Sbjct: 767  STEGS---ETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKM 823

Query: 1378 -------PDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430
                    + T +  T      V+ A S T  A T   A   T    S    ET    T 
Sbjct: 824  TTVFTENSETTIASTTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTE 880

Query: 1431 HTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQS 1490
             + TT  S  SS          +    ST+G     TS+    TT +ST    +TTV+ +
Sbjct: 881  GSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTT 940

Query: 1491 TPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLS 1550
                  +     E   +     +L       S +  +  E +E  + + T         S
Sbjct: 941  GSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTAS 998

Query: 1551 STGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTP 1609
            + G  ++   +AGS      +      T S     S   E    +  GT TT+  T  + 
Sbjct: 999  TAGSETTTVSTAGSETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSE 1053

Query: 1610 EELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQA 1665
                 TA +E  A      E    + +    +    V  TG    T+  A     TV+ +
Sbjct: 1054 TTTVTTAGSETTAVYTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTS 1110

Query: 1666 ELGHLSAEGQEGQATTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALA 1718
              G  +A     + TT+ I         T+   A  V     +   A      + T    
Sbjct: 1111 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1170

Query: 1719 PADSLNDPAIESNC-LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQ 1776
             +++     I S    +  AG+  +T +   S T T S A S T  A       + A   
Sbjct: 1171 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1230

Query: 1777 AAATLTEVANGIES 1790
             + T T    G E+
Sbjct: 1231 GSETNTACTTGSET 1244



 Score =  146 bits (369), Expect = 2e-34
 Identities = 260/1174 (22%), Positives = 425/1174 (36%), Gaps = 149/1174 (12%)

Query: 451  AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
            A+   P TT +      + TV  +      A+        +  TG + TT + + +    
Sbjct: 327  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 386

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566
                 +  T  S          T+ ++ T + ++   +   ++  +   T     S    
Sbjct: 387  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 446

Query: 567  VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619
            V +    TT   T        + +   TT  +T    ++ V  +   T+   T  ++  T
Sbjct: 447  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 504

Query: 620  SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679
            + +S T   T  + T+    T    + ++  TT V      +T V +  S    +  +S 
Sbjct: 505  TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 559

Query: 680  LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727
             G   + V T  ++T       S +T  ++TG  T    T+G        AG+    V++
Sbjct: 560  TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 619

Query: 728  ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780
            AD + TT  T    TT AS  G++ T    +S    + ST    TTT+  T   + +++ 
Sbjct: 620  ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 679

Query: 781  AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834
             G+   +TS+ G ++     T   T V T G+G     IT     K++T   +   T   
Sbjct: 680  TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 738

Query: 835  LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892
                    G+ + T  + G    T  T  +     TT   +G  TT  +T G+ T T ST
Sbjct: 739  -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 788

Query: 893  SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940
            + +     S   S  T  +T+G+    ++T SS++            A T ++  TT++ 
Sbjct: 789  TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 848

Query: 941  AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
            AG  T P  T       ++ T  T+  G E             + T    T T T     
Sbjct: 849  AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 900

Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060
                  G+ T   S    ET  T T  + TTT  A+  G    T      +   A+    
Sbjct: 901  ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 952

Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109
             +T     GS +   S    ET        ET T  T  + T T++ AG      S    
Sbjct: 953  ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 1012

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160
            ET       + TT +SS G+    +       GT   I          ++ A     A  
Sbjct: 1013 ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1068

Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217
             + S+  T  T  + TT TV  TG+     S   L   +++    G + A    +  ++ 
Sbjct: 1069 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1127

Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277
                S +      G  +  VST +   ++       M  V  ++   +  +T+   A  +
Sbjct: 1128 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1187

Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337
                S   T         T  T  + T T S AGS     S    ET+   TT + T+  
Sbjct: 1188 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1247

Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392
            S+ G+               ET+     G+ T   S  +L P AT    S   TV     
Sbjct: 1248 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1292

Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440
             A A S T  + T +L        Q + + P   T  TGT  TA++          T++ 
Sbjct: 1293 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1352

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            +S+  P    +  G   ST G S + TS+  + TT  ST     +T  ++    GP    
Sbjct: 1353 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1407

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534
               + +S  P   + P   LQ  +  L+  +A V
Sbjct: 1408 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1441



 Score =  140 bits (353), Expect = 1e-32
 Identities = 243/1113 (21%), Positives = 404/1113 (36%), Gaps = 114/1113 (10%)

Query: 718  AGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI 777
            AG+     ++AD K   +IT +  S   T     G ++ + STT   TTTI+     +  
Sbjct: 2    AGSEATTTSTADSK---VITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTT 58

Query: 778  ITQAGATGVTSSP-GIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836
             + AG+   T SP G ++ I  I+   +T+ + A ++  T     + G G    +    +
Sbjct: 59   ASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVS---SAGSGTTTASMAGSE 115

Query: 837  GAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAG 896
                  G+   TV + G    T V+    +    +     TT  +T G+ T TVST  + 
Sbjct: 116  STISTAGSETTTVSITGTE-TTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSE 174

Query: 897  AGGHSTSASLATPITTLG----TIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQ 952
                 T+ S  T  +T G    T+ T  S+ I P+  T  +  TT++ AG  TT T++  
Sbjct: 175  TTTAYTADSETTAASTTGSEMTTVFTAGSETITPS--TAGSETTTVSTAGSETT-TVSTT 231

Query: 953  PVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTV--- 1009
                 T  T  +  +           VS   S TT     + T A S + D +  T    
Sbjct: 232  GSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE-DSETNTAFTE 290

Query: 1010 ---TLVCSNPPCETHETGTTNT---------ATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
               T   S    ET    TT +         + TT+ + +G  P+ T+V        + A
Sbjct: 291  DSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIG--PETTKV--------STA 340

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
            S   +TV       +R  S    ET    TT + TT  S M           ET    TT
Sbjct: 341  SSEVTTVFAAGSETIRA-STVGSETTTVSTTGSETTTASIMGS---------ETSTDSTT 390

Query: 1118 NTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTT 1177
             + TT  S+ G+     +     A T +       T ++  ++ + +  +  + +A STT
Sbjct: 391  GSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTT 450

Query: 1178 MTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAV 1237
            +    T +   +   +  +   E    + A  + +  ++     S +      G  +   
Sbjct: 451  VFETTTASTEGSEITIASTSDSET---TTASTEGSETTTVTTAGSETKTAYTTGSETTTA 507

Query: 1238 STAAMTRSSVGA-GEPRMAPVCESLQGGSPSTTVTVTALE-ALLCPSATVTQVCSNPPCE 1295
            S   +  ++V   G        E    GS +T V+ T  E   +    +     S    E
Sbjct: 508  SNTGLETTTVFTIGSDTTTASTE----GSETTAVSATGSEMTTVSTEGSENTTVSTTGSE 563

Query: 1296 THETGTTN--TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPA 1353
            T    TT   T TTS  GS     S    ET    T  + TTA S  G+           
Sbjct: 564  TTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS----------- 612

Query: 1354 GRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPT 1413
                   +TT+  T  S +  A   D+ ++  +  +G E   A + + +  TA      T
Sbjct: 613  -------ETTTVSTADSENTTASTADSETTSAST-TGSETTTASTTSSETTTASTEGSET 664

Query: 1414 QRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAIT 1473
              V S    ET    TT +  T+TS   S      A   +  V +    +  ++ + + T
Sbjct: 665  TTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSET 723

Query: 1474 TTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGPRQQLPPRQLLQSASTALMGESA 1532
            T VS+T +   TT T+ + +   S+   E    S  G        +  ++ S +  G   
Sbjct: 724  TKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSET 783

Query: 1533 EVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSAVVATVVVQP-----PPPTQSEV 1582
               S + +    A++      ++ST    + + S  S+ + TV  +         T SE 
Sbjct: 784  TTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET 843

Query: 1583 DQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQA 1641
              +S    E +  + AG+ T   T     E    +   +    A+TE ++      +   
Sbjct: 844  TTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSE 903

Query: 1642 AQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQ 1701
               A     E   TS   +  T A     S EG E     I  V T          +  +
Sbjct: 904  TTTASTEGSETTTTSTEGSETTTA-----STEGSE-----ITTVSTTGSETTTASTEGSE 953

Query: 1702 EAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPS-TATESLAPSNT 1760
               A  +   L T +   ++++   A          G+  +TV  + S T T S A S T
Sbjct: 954  TTTASTEGSELTTVSTTGSETITVSA---------EGSETTTVTTMGSETTTASTAGSET 1004

Query: 1761 FVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
                      + A ++ + T T  + G E+  V
Sbjct: 1005 TTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1037



 Score =  124 bits (312), Expect = 7e-28
 Identities = 214/959 (22%), Positives = 336/959 (35%), Gaps = 105/959 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 477  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 534

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 535  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 594

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 595  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 654

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 655  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 711

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 712  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 762

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 763  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 817

Query: 727  SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            +A  K TT+ T    TT AS   ++ T +   G  ++  ST    TTT   T        
Sbjct: 818  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 877

Query: 780  QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836
                +  T++    S  T  TT   +  T+ T       T+     T       +++   
Sbjct: 878  STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 937

Query: 837  GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890
               G   T   T         T      TVS       T+  +G  TT VTT+G+ T T 
Sbjct: 938  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 997

Query: 891  STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945
            ST    AG  +T+ S A   TT  +I      T+SS     T ++ +  +TT+T+  G  
Sbjct: 998  ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1053

Query: 946  TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002
            T T+T          T  +  +    +      VS   S TT   TA   T T++ SG G
Sbjct: 1054 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1113

Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
                             G+ T   S    E     TT++ TTT  A+  G    T    V
Sbjct: 1114 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1171

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108
             +    +     +T     GS     S    ET    T  + TT  S    +    S   
Sbjct: 1172 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1231

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168
             ET+   TT + T+  SS G+    +   A   G+   I    +T +LE    S +  +T
Sbjct: 1232 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1284

Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215
               S T           S+T  V+      S  P+    M+  R  G R  A       S
Sbjct: 1285 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1337

Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269
            S V + +P + D  A   SH V     +T+ +  S++GA     A    +  G +   T
Sbjct: 1338 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1394



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%)

Query: 446  TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505
            T   + + A   +TT     T   +   + T   T      +   G +ATT +   +   
Sbjct: 1136 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1195

Query: 506  ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565
             +    +  T  S          T  ++ T   +S   +  A    +  +T     S   
Sbjct: 1196 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1255

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T   + + TTI  T ++ P  T+L  +    ++ V ++        T  +     ++ AT
Sbjct: 1256 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1312

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684
            + S +PI     SGT T   +    ++V        T   +  +VPG     S LG   M
Sbjct: 1313 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1372

Query: 685  SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736
                T        T  ++  P +   Q  GP+  GT      S    PT +I
Sbjct: 1373 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1421


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score =  161 bits (407), Expect = 7e-39
 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTI 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620
            GS    T        T S     +   E    + AG  TTT   +G        T +  +
Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
               +A +E   A  I +    A  A +   EP  TS   +  T      ++A G    +T
Sbjct: 1225 TPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278

Query: 1681 TI 1682
            T+
Sbjct: 1279 TV 1280



 Score =  153 bits (387), Expect = 1e-36
 Identities = 276/1294 (21%), Positives = 443/1294 (34%), Gaps = 117/1294 (9%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTT 1177
             +  T +S+ GA    D+     +GT A       T  +  A    +   T  +  TS +
Sbjct: 560  GSEMTTVSTTGAETTTDSTE--GSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617

Query: 1178 MTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAV 1237
             T   T    +A      +      G     V      + +  ++ S + + +   S   
Sbjct: 618  TTGSET---TTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETT 674

Query: 1238 STAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL-LCPSATVTQVCSNPPCET 1296
            + +A    +  + E            GS +TTV++T  E   +  + + T + S    E 
Sbjct: 675  TVSATGSETTVSTE------------GSGTTTVSITGSETTKVSTTGSETTITSTEGSEI 722

Query: 1297 HETGTT--NTATTSNAGSAQRVCSNPPCETHETGT----THTATTATSNGGTGQPEGGQQ 1350
                 T   T T S  GS     S    ET    T    T TA+T +S        G + 
Sbjct: 723  TTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSET 782

Query: 1351 PPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAP 1410
              A          ST ++   +V     + T +  T      V+ A S T  A T   A 
Sbjct: 783  TMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST---AG 839

Query: 1411 FPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSS 1470
              T    S    ET    T  + TT  S  SS          +    ST+G     TS+ 
Sbjct: 840  SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTE 899

Query: 1471 AITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGE 1530
               TT +ST    +TTV+ +      +     E   +     +L       S +  +  E
Sbjct: 900  GSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAE 959

Query: 1531 SAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE 1590
             +E  + + T         S+ G  ++   +AGS      +      T S     S   E
Sbjct: 960  GSE--TTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVS-----STGSE 1012

Query: 1591 LMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGT 1649
                +  GT TT+  T  +      TA +E  A      E    + +    +    V  T
Sbjct: 1013 TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEG---SETTTVSTT 1069

Query: 1650 GEPMDTSEAA----ATVTQAELGHLSAEGQEGQATTIPI-------VLTQQELAALVQQQ 1698
            G    T+  A     TV+ +  G  +A     + TT+ I         T+   A  V   
Sbjct: 1070 GSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTT 1129

Query: 1699 QLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC-LNELAGTVPSTVALLPS-TATESLA 1756
              +   A      + T     +++     I S    +  AG+  +T +   S T T S A
Sbjct: 1130 SSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTA 1189

Query: 1757 PSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
             S T  A       + A    + T T    G E+
Sbjct: 1190 GSETTTASTAGSETTTASTSGSETNTACTTGSET 1223



 Score =  147 bits (372), Expect = 8e-35
 Identities = 260/1174 (22%), Positives = 426/1174 (36%), Gaps = 149/1174 (12%)

Query: 451  AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
            A+   P TT +      + TV  +      A+        +  TG + TT + + +    
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566
                 +  T  S          T+ ++ T + ++   +   ++  +   T     S    
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 567  VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619
            V +    TT   T        + +   TT  +T    ++ V  +   T+   T  ++  T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483

Query: 620  SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679
            + +S T   T  + T+    T    + ++  TT V      +T V +  S    +  +S 
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538

Query: 680  LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727
             G   + V T  ++T       S +T  ++TG  T    T+G        AG+    V++
Sbjct: 539  TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598

Query: 728  ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780
            AD + TT  T    TT AS  G++ T    +S    + ST    TTT+  T   + +++ 
Sbjct: 599  ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658

Query: 781  AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834
             G+   +TS+ G ++     T   T V T G+G     IT     K++T   +  +T   
Sbjct: 659  TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITST- 717

Query: 835  LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892
                    G+ + T  + G    T  T  +     TT   +G  TT  +T G+ T T ST
Sbjct: 718  -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767

Query: 893  SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940
            + +     S   S  T  +T+G+    ++T SS++            A T ++  TT++ 
Sbjct: 768  TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827

Query: 941  AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
            AG  T P  T       ++ T  T+  G E             + T    T T T     
Sbjct: 828  AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879

Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060
                  G+ T   S    ET  T T  + TTT  A+  G    T      +   A+    
Sbjct: 880  ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931

Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109
             +T     GS +   S    ET        ET T  T  + T T++ AG      S    
Sbjct: 932  ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160
            ET       + TT +SS G+    +       GT   I          ++ A     A  
Sbjct: 992  ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047

Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217
             + S+  T  T  + TT TV  TG+     S   L   +++    G + A    +  ++ 
Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277
                S +      G  +  VST +   ++       M  V  ++   +  +T+   A  +
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166

Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337
                S   T         T  T  + T T S AGS     S    ET+   TT + T+  
Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226

Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGALLPDAT----SSHRTVESGLE 1392
            S+ G+               ET+     G+ T   S  +L P AT    S   TV     
Sbjct: 1227 SSAGS---------------ETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440
             A A S T  + T +L        Q + + P   T  TGT  TA++          T++ 
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            +S+  P    +  G   ST G S + TS+  + TT  ST     +T  ++    GP    
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534
               + +S  P   + P   LQ  +  L+  +A V
Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420



 Score =  138 bits (347), Expect = 6e-32
 Identities = 240/1135 (21%), Positives = 396/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +    T T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  125 bits (315), Expect = 3e-28
 Identities = 214/959 (22%), Positives = 337/959 (35%), Gaps = 105/959 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T+T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            +A  K TT+ T    TT AS   ++ T +   G  ++  ST    TTT   T        
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 780  QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836
                +  T++    S  T  TT   +  T+ T       T+     T       +++   
Sbjct: 857  STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 837  GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890
               G   T   T         T      TVS       T+  +G  TT VTT+G+ T T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976

Query: 891  STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945
            ST    AG  +T+ S A   TT  +I      T+SS     T ++ +  +TT+T+  G  
Sbjct: 977  ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032

Query: 946  TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002
            T T+T          T  +  +    +      VS   S TT   TA   T T++ SG G
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
                             G+ T   S    E     TT++ TTT  A+  G    T    V
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108
             +    +     +T     GS     S    ET    T  + TT  S    +    S   
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168
             ET+   TT + T+  SS G+    +   A   G+   I    +T +LE    S +  +T
Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSETTI---ASTASLEPTATSLTGSET 1263

Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215
               S T           S+T  V+      S  P+    M+  R  G R  A       S
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1316

Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269
            S V + +P + D  A   SH V     +T+ +  S++GA     A    +  G +   T
Sbjct: 1317 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373



 Score = 58.9 bits (141), Expect = 5e-08
 Identities = 59/292 (20%), Positives = 101/292 (34%), Gaps = 7/292 (2%)

Query: 446  TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505
            T   + + A   +TT     T   +   + T   T      +   G +ATT +   +   
Sbjct: 1115 TASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEAT 1174

Query: 506  ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565
             +    +  T  S          T  ++ T   +S   +  A    +  +T     S   
Sbjct: 1175 TTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETN 1234

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
            T   + + TTI  T ++ P  T+L  +    ++ V ++        T  +     ++ AT
Sbjct: 1235 TAFIIGSETTIASTASLEPTATSLTGS---ETTTVSITASGATAASTTVSSTTFVLTKAT 1291

Query: 626  NTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLG-KVM 684
            + S +PI     SGT T   +    ++V        T   +  +VPG     S LG   M
Sbjct: 1292 DVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASAASHTVPGIVLNTSGLGTSTM 1351

Query: 685  SVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736
                T        T  ++  P +   Q  GP+  GT      S    PT +I
Sbjct: 1352 GASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMGT---NTVSMSHTPTNVI 1400



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score =  161 bits (407), Expect = 7e-39
 Identities = 287/1322 (21%), Positives = 469/1322 (35%), Gaps = 138/1322 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG--TTTLMVTGLTPEELAVTAAAEA 1620
            GS    T        T S     +   E    + AG  TTT   +G        T +  +
Sbjct: 1170 GSEATTTSTEGSETTTAS-----TAGSETTTASTAGSETTTASTSGSETNTACTTGSETS 1224

Query: 1621 AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQAT 1680
               +A +E   A  I +    A  A +   EP  TS   +  T      ++A G    +T
Sbjct: 1225 TPSSAGSETNTAFIIGSESTIASTASL---EPTATSLTGSETTTVS---ITASGATAAST 1278

Query: 1681 TI 1682
            T+
Sbjct: 1279 TV 1280



 Score =  154 bits (389), Expect = 8e-37
 Identities = 288/1320 (21%), Positives = 444/1320 (33%), Gaps = 169/1320 (12%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             +  T +S+ GA    D+       AA T      +V+T   E    S +  +T   S T
Sbjct: 560  GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
             +  T  +T                                     SS +      G  +
Sbjct: 620  GSETTTAST------------------------------------TSSETTTASTEGSET 643

Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293
              VST     + V   G  R     E    GS +TTV+ T  E  +    + T   S   
Sbjct: 644  TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699

Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351
             ET +  TT   T TTS  GS     S    ET    T  + TT  S  G+   E     
Sbjct: 700  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756

Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384
              G    T  TTS+ TTM+  +G+                              + T + 
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             T      V+ A S T  A T   A   T    S    ET    T  + TT  S  SS  
Sbjct: 817  TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                    +    ST+G     TS+    TT +ST    +TTV+ +      +     E 
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564
              +     +L       S +  +  E +E  + + T         S+ G  ++   +AGS
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623
                  +      T S     S   E    +  GT TT+  T  +      TA +E  A 
Sbjct: 992  ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046

Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679
                 E    + +    +    V  TG    T+  A     TV+ +  G  +A     + 
Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732
            TT+ I         T+   A  V     +   A      + T     +++     I S  
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
              +  AG+  +T +   S T T S A S T  A       + A    + T T    G E+
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1223



 Score =  146 bits (369), Expect = 2e-34
 Identities = 259/1174 (22%), Positives = 426/1174 (36%), Gaps = 149/1174 (12%)

Query: 451  AAPAPPTTTTIQV----LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPA 506
            A+   P TT +      + TV  +      A+        +  TG + TT + + +    
Sbjct: 306  ASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETST 365

Query: 507  SQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT 566
                 +  T  S          T+ ++ T + ++   +   ++  +   T     S    
Sbjct: 366  DSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTA 425

Query: 567  VLSVPAGTTIVKT-------MAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGT 619
            V +    TT   T        + +   TT  +T    ++ V  +   T+   T  ++  T
Sbjct: 426  VSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSE--T 483

Query: 620  SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISN 679
            + +S T   T  + T+    T    + ++  TT V      +T V +  S    +  +S 
Sbjct: 484  TTASNTGLETTTVFTIGSDTTTASTEGSE--TTAVSATGSEMTTVSTEGSE---NTTVST 538

Query: 680  LGKVMSVVQTKPVQT-------SAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTS 727
             G   + V T  ++T       S +T  ++TG  T    T+G        AG+    V++
Sbjct: 539  TGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVST 598

Query: 728  ADGKPTTIIT----TTQASGAGTKPTILGISS---VSPSTTKPGTTTIIKTIPMSAIITQ 780
            AD + TT  T    TT AS  G++ T    +S    + ST    TTT+  T   + +++ 
Sbjct: 599  ADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVST 658

Query: 781  AGATG-VTSSPGIKSPITIIT---TKVMTSGTGAPAKIITA--VPKIATGHGQQGVTQVV 834
             G+   +TS+ G ++     T   T V T G+G     IT     K++T   +   T   
Sbjct: 659  TGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTST- 717

Query: 835  LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVST 892
                    G+ + T  + G    T  T  +     TT   +G  TT  +T G+ T T ST
Sbjct: 718  -------EGSEITTASITGSETTTASTEGS---ETTTASTEGSETTSASTTGSETTTAST 767

Query: 893  SLAGAGGHSTSASLATPITTLGT----IATLSSQVIN--------PTAITVSAAQTTLTA 940
            + +     S   S  T  +T+G+    ++T SS++            A T ++  TT++ 
Sbjct: 768  TSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVST 827

Query: 941  AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
            AG  T P  T       ++ T  T+  G E             + T    T T T     
Sbjct: 828  AGSETIPASTAG-----SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTI--- 879

Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060
                  G+ T   S    ET  T T  + TTT  A+  G    T      +   A+    
Sbjct: 880  ------GSETTTASTEGSETTTTSTEGSETTT--ASTEGSEITTVSTTGSETTTASTEGS 931

Query: 1061 TSTVGQQNGSVVRVCSNPPCET-------HETGTTNT--ATTATSNMAGQHGC--SNPPC 1109
             +T     GS +   S    ET        ET T  T  + T T++ AG      S    
Sbjct: 932  ETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIR---------ISVATGALEAAQ 1160
            ET       + TT +SS G+    +       GT   I          ++ A     A  
Sbjct: 992  ETTTASIEGSETTTVSSTGS----ETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVY 1047

Query: 1161 GSKSQCQTRQTSATSTTMTVMATGAP---CSAGPLLGPSMAREPGGRSPAFVQLAPLSSK 1217
             + S+  T  T  + TT TV  TG+     S   L   +++    G + A    +  ++ 
Sbjct: 1048 TTGSETTTTSTEGSETT-TVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTV 1106

Query: 1218 VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEA 1277
                S +      G  +  VST +   ++       M  V  ++   +  +T+   A  +
Sbjct: 1107 YITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTS 1166

Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTAT 1337
                S   T         T  T  + T T S AGS     S    ET+   TT + T+  
Sbjct: 1167 SAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTP 1226

Query: 1338 SNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSV-SVGALLPDAT----SSHRTVESGLE 1392
            S+ G+               ET+     G+  ++ S  +L P AT    S   TV     
Sbjct: 1227 SSAGS---------------ETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITAS 1271

Query: 1393 VAAAPSVTPQAGTALL---APFPTQRVCSNPPCETHETGTTHTATT---------VTSNM 1440
             A A S T  + T +L        Q + + P   T  TGT  TA++          T++ 
Sbjct: 1272 GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTASA 1331

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            +S+  P    +  G   ST G S + TS+  + TT  ST     +T  ++    GP    
Sbjct: 1332 ASHTVPGIVLNTSGLGTSTMGAS-STTSAHGVRTTTGSTREPTSSTFQET----GPVSMG 1386

Query: 1501 PEELQVSPGPRQQLPPRQLLQSASTALMGESAEV 1534
               + +S  P   + P   LQ  +  L+  +A V
Sbjct: 1387 TNTVSMSHTPTNVIKPSGYLQPWAIILISLAAVV 1420



 Score =  140 bits (353), Expect = 1e-32
 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +   TT T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  125 bits (313), Expect = 5e-28
 Identities = 214/959 (22%), Positives = 337/959 (35%), Gaps = 105/959 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAS-TGPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTIL---GISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            +A  K TT+ T    TT AS   ++ T +   G  ++  ST    TTT   T        
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTA 856

Query: 780  QAGATGVTSSPGIKSPITIITT---KVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLK 836
                +  T++    S  T  TT   +  T+ T       T+     T       +++   
Sbjct: 857  STEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTV 916

Query: 837  GAPGQPGTILRTVPMGGVRLVTP----VTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTV 890
               G   T   T         T      TVS       T+  +G  TT VTT+G+ T T 
Sbjct: 917  STTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTA 976

Query: 891  STSLAGAGGHSTSASLATPITTLGTI-----ATLSSQVINPTAITVSAAQTTLTAAGGLT 945
            ST    AG  +T+ S A   TT  +I      T+SS     T ++ +  +TT+T+  G  
Sbjct: 977  ST----AGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSE 1032

Query: 946  TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTA---TVTIADSGQG 1002
            T T+T          T  +  +    +      VS   S TT   TA   T T++ SG G
Sbjct: 1033 TTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSG 1092

Query: 1003 DVQ-------------PGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
                             G+ T   S    E     TT++ TTT  A+  G    T    V
Sbjct: 1093 TTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTT--ASTTGSEMTTVFTTV 1150

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQ-HGCSNPP 1108
             +    +     +T     GS     S    ET    T  + TT  S    +    S   
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168
             ET+   TT + T+  SS G+    +   A   G+ + I    +T +LE    S +  +T
Sbjct: 1211 SETNTACTTGSETSTPSSAGS----ETNTAFIIGSESTI---ASTASLEPTATSLTGSET 1263

Query: 1169 RQTSAT-----------STTMTVMATGAPCSAGPLLGPSMA--REPGGRSPAFVQLAPLS 1215
               S T           S+T  V+      S  P+    M+  R  G R  A       S
Sbjct: 1264 TTVSITASGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTA-------S 1316

Query: 1216 SKVRLSSPSIKDLPAGRHSHAV-----STAAMTRSSVGAGEPRMAPVCESLQGGSPSTT 1269
            S V + +P + D  A   SH V     +T+ +  S++GA     A    +  G +   T
Sbjct: 1317 SSVTM-APGM-DFTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPT 1373



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  160 bits (404), Expect = 2e-38
 Identities = 287/1327 (21%), Positives = 469/1327 (35%), Gaps = 138/1327 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQ-----LSLPQELMAEAQAG--TTTLMVTGLTPEELAVT 1615
            GS    T        T S          +   E    + AG  TTT   +G        T
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT 1229

Query: 1616 AAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQ 1675
             +  +   +A +E   A  I +    A  A +   EP  TS   +  T      ++A G 
Sbjct: 1230 GSETSTPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGA 1283

Query: 1676 EGQATTI 1682
               +TT+
Sbjct: 1284 TAASTTV 1290



 Score =  154 bits (390), Expect = 6e-37
 Identities = 288/1320 (21%), Positives = 445/1320 (33%), Gaps = 169/1320 (12%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             +  T +S+ GA    D+       AA T      +V+T   E    S +  +T   S T
Sbjct: 560  GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
             +  T  +T                                     SS +      G  +
Sbjct: 620  GSETTTAST------------------------------------TSSETTTASTEGSET 643

Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293
              VST     + V   G  R     E    GS +TTV+ T  E  +    + T   S   
Sbjct: 644  TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699

Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351
             ET +  TT   T TTS  GS     S    ET    T  + TT  S  G+   E     
Sbjct: 700  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756

Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384
              G    T  TTS+ TTM+  +G+                              + T + 
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             T      V+ A S T  A T   A   T    S    ET    T  + TT  S  SS  
Sbjct: 817  TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                    +    ST+G     TS+    TT +ST    +TTV+ +      +     E 
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564
              +     +L       S +  +  E +E  + + T         S+ G  ++   +AGS
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623
                  +      T S     S   E    +  GT TT+  T  +      TA +E  A 
Sbjct: 992  ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046

Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679
                 E    + +    +    V  TG    T+  A     TV+ +  G  +A     + 
Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732
            TT+ I         T+   A  V     +   A      + T     +++     I S  
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
              +  AG+  +T +   S T T S A S T  A       + A    + T T   +G E+
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSET 1223



 Score =  140 bits (353), Expect = 1e-32
 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +   TT T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  122 bits (306), Expect = 4e-27
 Identities = 228/1027 (22%), Positives = 364/1027 (35%), Gaps = 108/1027 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAST-GPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG 782
            +A  K TT+ T    TT AS   ++ T +   S + S T P +T   +T   ++  T+  
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTV---STAGSETIPASTAGSETTTTTS--TEGS 851

Query: 783  ATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842
             T   S+ G ++     TT    S     A  I +    A+  G +  T           
Sbjct: 852  ETTTASTEGSET-----TTASTESSETTTATTIGSETTTASTEGSETTTT-------STE 899

Query: 843  GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVSTSLAGAGGH 900
            G+   T    G  + T   VS      TT   +G  TT  +T G+   TVST+ +     
Sbjct: 900  GSETTTASTEGSEITT---VSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 901  STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960
            S   S  T +TT+G+  T        TA T  +  TT++ AG  TT        S     
Sbjct: 957  SAEGSETTTVTTMGSETT--------TASTAGSETTTVSTAGSETT------TASIEGSE 1002

Query: 961  TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV-QPGTVTLVCSNPPCE 1019
            T   + +G E   V         + T    T TVT A S    V   G+ T   S    E
Sbjct: 1003 TTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062

Query: 1020 THETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPP 1079
            T    TT + TTT             ++        + +   ST G +  +V    S   
Sbjct: 1063 TTTVSTTGSETTTA--------STADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1080 CETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRAC 1139
              + E     T +T +S        S    E     TT + TT +S++G+    +A  + 
Sbjct: 1115 TASTEGSEATTVSTTSSETT---TASTTGSEMTTVFTTVSETTTVSTIGS----EATTSS 1167

Query: 1140 AAGTPAVIRISVATGALEAAQGSKSQCQTRQTS-ATSTTMTVMATGAPCSAGPLLGPSMA 1198
            AAG+ A    + +T   E    S +  +T   S A S T T    G+  +     G    
Sbjct: 1168 AAGSEAT---TTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE-- 1222

Query: 1199 REPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAM--TRSSVGAGEPRMAP 1256
                  + A    +  S+     S +      G  +   STA++  T +S+   E     
Sbjct: 1223 -----TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVS 1277

Query: 1257 VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS-------- 1308
            +  S    + STTV+ T          ++  + + P   T  TGT  TA++S        
Sbjct: 1278 ITAS-GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1336

Query: 1309 -NAGSAQRVCSNPPCETHETGT-THTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTG 1366
              A +A          T   GT T  A++ TS  G     G  + P     +     S G
Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMG 1396

Query: 1367 T-TMSVS 1372
            T T+S+S
Sbjct: 1397 TNTVSMS 1403



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  160 bits (404), Expect = 2e-38
 Identities = 287/1327 (21%), Positives = 469/1327 (35%), Gaps = 138/1327 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQ-----LSLPQELMAEAQAG--TTTLMVTGLTPEELAVT 1615
            GS    T        T S          +   E    + AG  TTT   +G        T
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT 1229

Query: 1616 AAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQ 1675
             +  +   +A +E   A  I +    A  A +   EP  TS   +  T      ++A G 
Sbjct: 1230 GSETSTPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGA 1283

Query: 1676 EGQATTI 1682
               +TT+
Sbjct: 1284 TAASTTV 1290



 Score =  154 bits (390), Expect = 6e-37
 Identities = 288/1320 (21%), Positives = 445/1320 (33%), Gaps = 169/1320 (12%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             +  T +S+ GA    D+       AA T      +V+T   E    S +  +T   S T
Sbjct: 560  GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
             +  T  +T                                     SS +      G  +
Sbjct: 620  GSETTTAST------------------------------------TSSETTTASTEGSET 643

Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293
              VST     + V   G  R     E    GS +TTV+ T  E  +    + T   S   
Sbjct: 644  TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699

Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351
             ET +  TT   T TTS  GS     S    ET    T  + TT  S  G+   E     
Sbjct: 700  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756

Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384
              G    T  TTS+ TTM+  +G+                              + T + 
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             T      V+ A S T  A T   A   T    S    ET    T  + TT  S  SS  
Sbjct: 817  TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                    +    ST+G     TS+    TT +ST    +TTV+ +      +     E 
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564
              +     +L       S +  +  E +E  + + T         S+ G  ++   +AGS
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623
                  +      T S     S   E    +  GT TT+  T  +      TA +E  A 
Sbjct: 992  ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046

Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679
                 E    + +    +    V  TG    T+  A     TV+ +  G  +A     + 
Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732
            TT+ I         T+   A  V     +   A      + T     +++     I S  
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
              +  AG+  +T +   S T T S A S T  A       + A    + T T   +G E+
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSET 1223



 Score =  140 bits (353), Expect = 1e-32
 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +   TT T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  122 bits (306), Expect = 4e-27
 Identities = 228/1027 (22%), Positives = 364/1027 (35%), Gaps = 108/1027 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAST-GPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG 782
            +A  K TT+ T    TT AS   ++ T +   S + S T P +T   +T   ++  T+  
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTV---STAGSETIPASTAGSETTTTTS--TEGS 851

Query: 783  ATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842
             T   S+ G ++     TT    S     A  I +    A+  G +  T           
Sbjct: 852  ETTTASTEGSET-----TTASTESSETTTATTIGSETTTASTEGSETTTT-------STE 899

Query: 843  GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVSTSLAGAGGH 900
            G+   T    G  + T   VS      TT   +G  TT  +T G+   TVST+ +     
Sbjct: 900  GSETTTASTEGSEITT---VSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 901  STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960
            S   S  T +TT+G+  T        TA T  +  TT++ AG  TT        S     
Sbjct: 957  SAEGSETTTVTTMGSETT--------TASTAGSETTTVSTAGSETT------TASIEGSE 1002

Query: 961  TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV-QPGTVTLVCSNPPCE 1019
            T   + +G E   V         + T    T TVT A S    V   G+ T   S    E
Sbjct: 1003 TTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062

Query: 1020 THETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPP 1079
            T    TT + TTT             ++        + +   ST G +  +V    S   
Sbjct: 1063 TTTVSTTGSETTTA--------STADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1080 CETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRAC 1139
              + E     T +T +S        S    E     TT + TT +S++G+    +A  + 
Sbjct: 1115 TASTEGSEATTVSTTSSETT---TASTTGSEMTTVFTTVSETTTVSTIGS----EATTSS 1167

Query: 1140 AAGTPAVIRISVATGALEAAQGSKSQCQTRQTS-ATSTTMTVMATGAPCSAGPLLGPSMA 1198
            AAG+ A    + +T   E    S +  +T   S A S T T    G+  +     G    
Sbjct: 1168 AAGSEAT---TTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE-- 1222

Query: 1199 REPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAM--TRSSVGAGEPRMAP 1256
                  + A    +  S+     S +      G  +   STA++  T +S+   E     
Sbjct: 1223 -----TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVS 1277

Query: 1257 VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS-------- 1308
            +  S    + STTV+ T          ++  + + P   T  TGT  TA++S        
Sbjct: 1278 ITAS-GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1336

Query: 1309 -NAGSAQRVCSNPPCETHETGT-THTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTG 1366
              A +A          T   GT T  A++ TS  G     G  + P     +     S G
Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMG 1396

Query: 1367 T-TMSVS 1372
            T T+S+S
Sbjct: 1397 TNTVSMS 1403



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score =  160 bits (404), Expect = 2e-38
 Identities = 287/1327 (21%), Positives = 469/1327 (35%), Gaps = 138/1327 (10%)

Query: 419  SVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAA 478
            S   +   +P+P  +   +  ++   IT    A     T ++     T    + S  T +
Sbjct: 39   STAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVS 98

Query: 479  RTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI- 537
                    + +TG + T  + + +    +    +  TVTS        V T  ++ T   
Sbjct: 99   TAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAY 158

Query: 538  -----GSSPQMSGMAALAAAAAATQKIPPSSA----PTVLSVPAGTTIVKTMAVTPGTTT 588
                  ++   +G        A ++ I PS+A     TV +  + TT V T   T   TT
Sbjct: 159  TADSETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVST---TGSETT 215

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              +T    ++        T  + TA ++  T+VS+A + +T       ++ T        
Sbjct: 216  TASTAHSETTAASTMGSETTKVSTAGSE--TTVSTAGSETTAASTEDSETNTAFTEDSKT 273

Query: 649  VVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQ 708
               +  G  T   +   S         + S +G   ++  T   +T+ V+  AS+   T 
Sbjct: 274  TTASTTGFETTAASTTGSE------PTMASTMGSETTMASTIGPETTKVS-TASSEVTTV 326

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
                   + A T+        G  TT ++TT      T  +I+G  + + STT   TTT 
Sbjct: 327  FAAGSETIRASTV--------GSETTTVSTT--GSETTTASIMGSETSTDSTTGSETTTA 376

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK--IATGHG 826
                  +   +  G+   T S       T+  T   T+ T      +TAV      T   
Sbjct: 377  STEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTA 436

Query: 827  QQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTV-SAVKPAVTTLVVKGTTGVTTLGT 885
                +++ +        T   T    G    T  T  S  K A TT     TT  +  G 
Sbjct: 437  STEGSEITIASTSDSETT---TASTEGSETTTVTTAGSETKTAYTT--GSETTTASNTGL 491

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGT-IATLSSQVINPTAITVSAAQTTLTAAGGL 944
             T TV T  +     ST  S  T ++  G+ + T+S++    T ++ + ++TT  +  GL
Sbjct: 492  ETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGL 551

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV 1004
             T T + +     T  T     +G E            A+ T    T TV+ ADS     
Sbjct: 552  ETTTTSTEGSEMTTVST-----TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 1005 QPG-TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
                + T   S    ET    TT++ TTT  A+  G    T         ++  ++V++T
Sbjct: 607  STADSETTSASTTGSETTTASTTSSETTT--ASTEGSETTT-----VSTTDSETTMVSTT 659

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                 GS   + S    ET     T + TT ++  +G    S    ET +  TT + TT 
Sbjct: 660  -----GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTT 714

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             S+ G+             T ++      T + E ++ + +  +  +T++ STT +   T
Sbjct: 715  TSTEGSE----------ITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTT 764

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMT 1243
             +  S+   +   M  E    S         S   ++S+ S K       +   + A+ T
Sbjct: 765  ASTTSSETTMASIMGSETTMASTIG------SETTKVSTASSKMTTVFTENSETTIASTT 818

Query: 1244 RSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTN 1303
             S         +    +   GS +TT T T        S T T         T  T ++ 
Sbjct: 819  ASETTTVSTAGSETIPASTAGSETTTTTSTE------GSETTTASTEGSETTTASTESSE 872

Query: 1304 TATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGG--------------TGQPEGGQ 1349
            T T +  GS     S    ET  T T  + TT  S  G              T   EG +
Sbjct: 873  TTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSE 932

Query: 1350 QPPAGRPCETHQTTSTGTTMSVSVGALLPDATS-----SHRTVES--GLEVAAAPSVTPQ 1402
               A        T ST  + +++V A   + T+     S  T  S  G E     +   +
Sbjct: 933  TTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSE 992

Query: 1403 AGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGD 1462
              TA +    T  V S+   ET    TT T TT+TS   S       A  +     T G 
Sbjct: 993  TTTASIEGSETTTV-SSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGS 1051

Query: 1463 SVNITSS-SAITTTVSSTLTRAVT-------TVTQSTPVPGPSVPPPEELQVS----PGP 1510
                TS+  + TTTVS+T +   T       T T ST   G +       + +     G 
Sbjct: 1052 ETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGS 1111

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQT--------PELPAAVDLSSTGEPSSGQESA 1562
            +      +   S +T +   S+E  +AS T          +     +S+ G  ++   +A
Sbjct: 1112 KTTTASTE--GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAA 1169

Query: 1563 GSAVVATVVVQPPPPTQSEVDQ-----LSLPQELMAEAQAG--TTTLMVTGLTPEELAVT 1615
            GS    T        T S          +   E    + AG  TTT   +G        T
Sbjct: 1170 GSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTT 1229

Query: 1616 AAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQ 1675
             +  +   +A +E   A  I +    A  A +   EP  TS   +  T      ++A G 
Sbjct: 1230 GSETSTPSSAGSETNTAFIIGSETTIASTASL---EPTATSLTGSETTTVS---ITASGA 1283

Query: 1676 EGQATTI 1682
               +TT+
Sbjct: 1284 TAASTTV 1290



 Score =  154 bits (390), Expect = 6e-37
 Identities = 288/1320 (21%), Positives = 445/1320 (33%), Gaps = 169/1320 (12%)

Query: 543  MSGMAALAAAAAA---TQKIPPSSAPTVLSVPAGTTIVKTM---AVTPGTTTLPATVKVA 596
            MS    +A AA +   T     S   T+L   + TT   T      TP  T    T+   
Sbjct: 1    MSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSI 60

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--V 654
            S   + +        T  +  G+  ++A+   +   ++   S T TV+      T V  +
Sbjct: 61   SGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAM 120

Query: 655  GGVTKTITLVKSPISVP----GGSALISNLGKVMSVVQTKPVQTSA--VTGQASTGPVTQ 708
            G  T T +   S  +V       +  +S +G   +   T   +T+A   TG   T   T 
Sbjct: 121  GSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTA 180

Query: 709  IIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI 768
              +T  P  AG+    V++A  + TT+ TT    G+ T       S  + ++T    TT 
Sbjct: 181  GSETITPSTAGSETTTVSTAGSETTTVSTT----GSETTTASTAHSETTAASTMGSETTK 236

Query: 769  IKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQ 828
            + T      ++ AG+    +S       T  T    T+         TA     TG    
Sbjct: 237  VSTAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAAS--TTG---- 290

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTV 886
              ++  +    G   T+  T+     +      VS     VTT+   G  T   +T+G+ 
Sbjct: 291  --SEPTMASTMGSETTMASTIGPETTK------VSTASSEVTTVFAAGSETIRASTVGSE 342

Query: 887  TGTVSTSLAGAGGHSTSASL-----ATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T TVST+    G  +T+AS+     +T  TT     T S++    T  +   ++ T  + 
Sbjct: 343  TTTVSTT----GSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVST 398

Query: 942  GGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G  T T+++      T  T        E   +  +  ++  + T     + +TIA +  
Sbjct: 399  TGSETTTVSITDSETTTTCT--------EGSEMTAVSTTVFETTTASTEGSEITIASTSD 450

Query: 1002 GDV----QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
             +       G+ T   +    ET    TT + TTT  A+  G    T      D   A+ 
Sbjct: 451  SETTTASTEGSETTTVTTAGSETKTAYTTGSETTT--ASNTGLETTTVFTIGSDTTTAST 508

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
                +T     GS +   S    E     TT + TT  S             ET  T T 
Sbjct: 509  EGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTG---------LETTTTSTE 559

Query: 1118 NTATTAMSSVGANHQRDARR---ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             +  T +S+ GA    D+       AA T      +V+T   E    S +  +T   S T
Sbjct: 560  GSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTT 619

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
             +  T  +T                                     SS +      G  +
Sbjct: 620  GSETTTAST------------------------------------TSSETTTASTEGSET 643

Query: 1235 HAVSTAAMTRSSVG-AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPP 1293
              VST     + V   G  R     E    GS +TTV+ T  E  +    + T   S   
Sbjct: 644  TTVSTTDSETTMVSTTGSERTITSTE----GSETTTVSATGSETTVSTEGSGTTTVSITG 699

Query: 1294 CETHETGTT--NTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQP 1351
             ET +  TT   T TTS  GS     S    ET    T  + TT  S  G+   E     
Sbjct: 700  SETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGS---ETTSAS 756

Query: 1352 PAGRPCETHQTTSTGTTMSVSVGALL---------------------------PDATSSH 1384
              G    T  TTS+ TTM+  +G+                              + T + 
Sbjct: 757  TTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIAS 816

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             T      V+ A S T  A T   A   T    S    ET    T  + TT  S  SS  
Sbjct: 817  TTASETTTVSTAGSETIPAST---AGSETTTTTSTEGSETTTASTEGSETTTASTESSET 873

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                    +    ST+G     TS+    TT +ST    +TTV+ +      +     E 
Sbjct: 874  TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSET 933

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGS 1564
              +     +L       S +  +  E +E  + + T         S+ G  ++   +AGS
Sbjct: 934  TTASTEGSELTTVSTTGSETITVSAEGSE--TTTVTTMGSETTTASTAGSETTTVSTAGS 991

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT-TTLMVTGLTPEELAVTAAAEAAAQ 1623
                  +      T S     S   E    +  GT TT+  T  +      TA +E  A 
Sbjct: 992  ETTTASIEGSETTTVS-----STGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAV 1046

Query: 1624 AAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAA----ATVTQAELGHLSAEGQEGQA 1679
                 E    + +    +    V  TG    T+  A     TV+ +  G  +A     + 
Sbjct: 1047 YTTGSETTTTSTEG---SETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSET 1103

Query: 1680 TTIPI-------VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNC 1732
            TT+ I         T+   A  V     +   A      + T     +++     I S  
Sbjct: 1104 TTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEA 1163

Query: 1733 -LNELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIES 1790
              +  AG+  +T +   S T T S A S T  A       + A    + T T   +G E+
Sbjct: 1164 TTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSET 1223



 Score =  140 bits (353), Expect = 1e-32
 Identities = 241/1135 (21%), Positives = 397/1135 (34%), Gaps = 152/1135 (13%)

Query: 681  GKVMSVVQTKPVQTSAVTGQAS--TGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT- 737
            G   +   T   +T+ +  +AS  T   T   +T  P P G+   +V+ +  + TT  T 
Sbjct: 12   GSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTA 71

Query: 738  -----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
                 T  ++G+GT    +  S  + ST    TTT+  T   + +++  G+   T+S   
Sbjct: 72   GSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNS--- 128

Query: 793  KSPITIITTKVMTSGTGAPAKIITAV-PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                T  +   +TS  G+    ++ V  +  T +     T      A    G+ + TV  
Sbjct: 129  ----TTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETT-----AASTTGSEMTTVFT 179

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT 911
             G   +TP T  +    V+T   + TT V+T G+ T T ST+ +     ST  S  T ++
Sbjct: 180  AGSETITPSTAGSETTTVSTAGSETTT-VSTTGSETTTASTAHSETTAASTMGSETTKVS 238

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEA 971
            T G+  T+S+     TA +   ++T         T T +          T  + P+    
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMAST 298

Query: 972  QPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
                    S +   TT+  TA+  +          G+ T+  S    ET    TT + TT
Sbjct: 299  MGSETTMASTIGPETTKVSTASSEVTTV----FAAGSETIRASTVGSETTTVSTTGSETT 354

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            T  A++ G    T      +   A+     +T     GS     S    ET     T++ 
Sbjct: 355  T--ASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSE 412

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            TT T              E     TT   TT  S+ G+                 I I+ 
Sbjct: 413  TTTTCTEGS---------EMTAVSTTVFETTTASTEGSE----------------ITIAS 447

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             + +      ++    T  T+A S T T   TG+  +                       
Sbjct: 448  TSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTT---------------------- 485

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
               +S   L + ++  +  G  +   ST     ++V A    M  V      GS +TTV+
Sbjct: 486  ---ASNTGLETTTVFTI--GSDTTTASTEGSETTAVSATGSEMTTVSTE---GSENTTVS 537

Query: 1272 VTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTH 1331
             T  E                   T  T    T TTS  GS     S    ET    T  
Sbjct: 538  TTGSETT-----------------TVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEG 580

Query: 1332 TATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            + TTA S  G+                  +TT+  T  S +  A   D+ ++  +  +G 
Sbjct: 581  SGTTAASTAGS------------------ETTTVSTADSENTTASTADSETTSAST-TGS 621

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            E   A + + +  TA      T  V S    ET    TT +  T+TS   S      A  
Sbjct: 622  ETTTASTTSSETTTASTEGSETTTV-STTDSETTMVSTTGSERTITSTEGSETTTVSATG 680

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS-PGP 1510
             +  V +    +  ++ + + TT VS+T +   TT T+ + +   S+   E    S  G 
Sbjct: 681  SETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGS 740

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV-----DLSSTGEPSSGQESAGSA 1565
                   +  ++ S +  G      S + +    A++      ++ST    + + S  S+
Sbjct: 741  ETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASS 800

Query: 1566 VVATVVVQP-----PPPTQSEVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAE 1619
             + TV  +         T SE   +S    E +  + AG+ T   T     E    +   
Sbjct: 801  KMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGSETTTASTEG 860

Query: 1620 AAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQA 1679
            +    A+TE ++      +      A     E   TS   +  T A     S EG E   
Sbjct: 861  SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTA-----STEGSE--- 912

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGT 1739
              I  V T          +  +   A  +   L T +   ++++   A          G+
Sbjct: 913  --ITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSA---------EGS 961

Query: 1740 VPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGV 1793
              +TV  + S T T S A S T          + A ++ + T T  + G E+  V
Sbjct: 962  ETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTV 1016



 Score =  122 bits (306), Expect = 4e-27
 Identities = 228/1027 (22%), Positives = 364/1027 (35%), Gaps = 108/1027 (10%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
            A+T   E +   V TA S            T A+ T      V ++ ++   +    +  
Sbjct: 456  ASTEGSETT--TVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSET 513

Query: 435  PAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQA 494
             AV        T+  + +     +TT     TV  + +   T +        +  TG + 
Sbjct: 514  TAVSATGSEMTTVSTEGSENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAET 573

Query: 495  TTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAA 554
            TT +   +   A+    +  T  S          T  ++ T   ++   +  A+  ++  
Sbjct: 574  TTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSET 633

Query: 555  ATQKIPPSSAPTVLSVPAGTTIV------KTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             T     S   TV +  + TT+V      +T+  T G+ T   TV    S   VS   + 
Sbjct: 634  TTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSET--TTVSATGSETTVSTEGS- 690

Query: 609  MLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVT-TVVGGVTKTITLVKSP 667
                     GT+  S T + T  + T     T T  + +++ T ++ G  T T +   S 
Sbjct: 691  ---------GTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSE 741

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQAST-GPVTQIIQTKGPLPAGTILKLVT 726
             +        +          T    TS+ T  AS  G  T +  T      G+    V+
Sbjct: 742  TTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMAST-----IGSETTKVS 796

Query: 727  SADGKPTTIIT----TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG 782
            +A  K TT+ T    TT AS   ++ T +   S + S T P +T   +T   ++  T+  
Sbjct: 797  TASSKMTTVFTENSETTIASTTASETTTV---STAGSETIPASTAGSETTTTTS--TEGS 851

Query: 783  ATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842
             T   S+ G ++     TT    S     A  I +    A+  G +  T           
Sbjct: 852  ETTTASTEGSET-----TTASTESSETTTATTIGSETTTASTEGSETTTT-------STE 899

Query: 843  GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKG--TTGVTTLGTVTGTVSTSLAGAGGH 900
            G+   T    G  + T   VS      TT   +G  TT  +T G+   TVST+ +     
Sbjct: 900  GSETTTASTEGSEITT---VSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITV 956

Query: 901  STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960
            S   S  T +TT+G+  T        TA T  +  TT++ AG  TT        S     
Sbjct: 957  SAEGSETTTVTTMGSETT--------TASTAGSETTTVSTAGSETT------TASIEGSE 1002

Query: 961  TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV-QPGTVTLVCSNPPCE 1019
            T   + +G E   V         + T    T TVT A S    V   G+ T   S    E
Sbjct: 1003 TTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSE 1062

Query: 1020 THETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPP 1079
            T    TT + TTT             ++        + +   ST G +  +V    S   
Sbjct: 1063 TTTVSTTGSETTTA--------STADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTT 1114

Query: 1080 CETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRAC 1139
              + E     T +T +S        S    E     TT + TT +S++G+    +A  + 
Sbjct: 1115 TASTEGSEATTVSTTSSETT---TASTTGSEMTTVFTTVSETTTVSTIGS----EATTSS 1167

Query: 1140 AAGTPAVIRISVATGALEAAQGSKSQCQTRQTS-ATSTTMTVMATGAPCSAGPLLGPSMA 1198
            AAG+ A    + +T   E    S +  +T   S A S T T    G+  +     G    
Sbjct: 1168 AAGSEAT---TTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE-- 1222

Query: 1199 REPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAM--TRSSVGAGEPRMAP 1256
                  + A    +  S+     S +      G  +   STA++  T +S+   E     
Sbjct: 1223 -----TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVS 1277

Query: 1257 VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS-------- 1308
            +  S    + STTV+ T          ++  + + P   T  TGT  TA++S        
Sbjct: 1278 ITAS-GATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMD 1336

Query: 1309 -NAGSAQRVCSNPPCETHETGT-THTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTG 1366
              A +A          T   GT T  A++ TS  G     G  + P     +     S G
Sbjct: 1337 FTASAASHTVPGIVLNTSGLGTSTMGASSTTSAHGVRTTTGSTREPTSSTFQETGPVSMG 1396

Query: 1367 T-TMSVS 1372
            T T+S+S
Sbjct: 1397 TNTVSMS 1403



 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 86/434 (19%), Positives = 155/434 (35%), Gaps = 33/434 (7%)

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE 1423
            S+ TT++ + G+    A+++     + L  A+  +    AG+    P PT    +     
Sbjct: 2    SSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSIS 61

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
              E  TT TA +  + +SS       A       S  G    ++++ + TTTVS T T  
Sbjct: 62   GSEITTTSTAGSENTTVSS-------AGSGTTTASMAGSETTVSTAGSETTTVSITGTET 114

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                   +     S    E    S    +      +    +TA   +S    +++   E+
Sbjct: 115  TMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEM 174

Query: 1544 PAAVDL-SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP-QELMAEAQAGTTT 1601
                   S T  PS+      +   A         T SE    S    E  A +  G+ T
Sbjct: 175  TTVFTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSET 234

Query: 1602 LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
              V+    E    TA +E    AA+TE+++                 T    D+    A+
Sbjct: 235  TKVSTAGSETTVSTAGSETT--AASTEDSET---------------NTAFTEDSKTTTAS 277

Query: 1662 VTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPAD 1721
             T  E    S  G E   T    + ++  +A+ +  +  + + A  +   + T   A ++
Sbjct: 278  TTGFETTAASTTGSE--PTMASTMGSETTMASTIGPETTKVSTASSE---VTTVFAAGSE 332

Query: 1722 SLNDPAIESNCLN-ELAGTVPSTVALLPS-TATESLAPSNTFVAPQPVVVASPAKLQAAA 1779
            ++    + S        G+  +T +++ S T+T+S   S T  A       + A  + + 
Sbjct: 333  TIRASTVGSETTTVSTTGSETTTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSE 392

Query: 1780 TLTEVANGIESLGV 1793
              T    G E+  V
Sbjct: 393  ATTVSTTGSETTTV 406


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score =  149 bits (376), Expect = 3e-35
 Identities = 358/1587 (22%), Positives = 554/1587 (34%), Gaps = 273/1587 (17%)

Query: 361  TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV 420
            T +  PP +V    A T ++  S    +++      L     PA  +TAT+PT   V  +
Sbjct: 2622 TLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATAL-----PALRSTATTPTATSVTPI 2676

Query: 421  PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPP-TTTTIQVLPTVPGSSISVPTAAR 479
            P++   +     +       T    T  P + P    T+T +    T  G++ SV T + 
Sbjct: 2677 PSSSLGTTWTRLSQTTTPTATMS--TATPSSTPETAHTSTVLTATATTTGATGSVATPSS 2734

Query: 480  TQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAP-----VTVTSLPAGVRMVVPTQSAQG 534
            T G     KV     TT T   T  P+S  G A      ++ T+ P      V   S  G
Sbjct: 2735 TPGTAHTTKVP----TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPG 2790

Query: 535  TVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPA--- 591
            T   ++   +    +A  + AT    PSS+           +  TMA T G +  P+   
Sbjct: 2791 TTHTATVLTTTTTTVATGSMAT----PSSSTQTSGTTHTPPVPNTMATTHGRSLPPSSPH 2846

Query: 592  TVKVA----SSPVM----VSNPATRMLKTAAAQVGTSV-----------SSATNTS---- 628
            TV+ A    +S ++    ++ P+T    T AA  GT+            SS T  S    
Sbjct: 2847 TVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSP 2906

Query: 629  --TRPIITVHKSGTVTVAQQAQVVTTVV-------GGVTKTITLVKSP-----------I 668
              T P  T   S T   A  ++  T+ +         +T  +T+   P            
Sbjct: 2907 GTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSY 2966

Query: 669  SVPGGSA----LISNLGKVMSVVQTKPVQTSAVTGQASTG-PVTQIIQT-KGPLPAGTIL 722
             +PG S       SN+      V  +P+       QA  G P+ ++ Q  +  L  G + 
Sbjct: 2967 PMPGPSGGDFDTYSNIRAAGGAVCEQPLGLEC-RAQAQPGVPLRELGQVVECSLDFGLVC 3025

Query: 723  KLVTSADGKPTTIIT---TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIIT 779
            +      GK                G  P+    SS +  ++ PGTT I+  +  +A  T
Sbjct: 3026 RNREQV-GKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTT 3084

Query: 780  QAGATGVTSSPGIKSPITII-----TTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVV 834
            ++  TG T++P      T I     TT  +T  TG+ A   +      T H     T   
Sbjct: 3085 ES--TGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT 3142

Query: 835  LKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVT-GTVSTS 893
            +  +   P +             +P T +A+    +T      T  T + + + GT  T 
Sbjct: 3143 VTSSKATPFS-------------SPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTR 3189

Query: 894  LAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQP 953
            L+     + + S ATP +T  T+ T  S V+  TA       TT  A G + TP+ T  P
Sbjct: 3190 LSQTTTPTATMSTATPSSTPETVHT--STVLTTTA-------TTTGATGSVATPSST--P 3238

Query: 954  VSQPTQVTLITAPSGVEAQP------VHDLPVSILASPTTEQPTATVTIADSGQGDVQPG 1007
             +  T   L T  +G  A P         LPV I  + T     +TVT          P 
Sbjct: 3239 GTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVT----------PS 3288

Query: 1008 TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQ 1067
            ++       P  TH T T  T TTT VA  G    P+               V +T    
Sbjct: 3289 SI-------PGTTH-TPTVLTTTTTTVAT-GSMATPSSSTQTSGTTHTPP--VPNTTATT 3337

Query: 1068 NGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSV 1127
            +G  +   S     T  T  T+     T       G S+ P  T  TGTT  +T A+SS 
Sbjct: 3338 HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT--TGTTQHSTPALSSP 3395

Query: 1128 -GANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT----RQTSATSTTMTVMA 1182
              ++   ++  +    TP   R +  T A   A  SK++  T      TSA  TT+  M 
Sbjct: 3396 HPSSRTTESPPSPGTTTPGHTRATSRTTA--TATPSKTRTSTLLPSSPTSAPITTVVTMG 3453

Query: 1183 TGAPCS-------AGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSH 1235
                C+       + P+ GPS     GG    +       S +R +  ++ + P G    
Sbjct: 3454 CEPQCAWSEWLDYSYPMPGPS-----GGDFDTY-------SNIRAAGGAVCEQPLGLECR 3501

Query: 1236 AVSTAAMTRSSVG------------------AGEPRM--------------------APV 1257
            A +   +    +G                   G+ +M                    A  
Sbjct: 3502 AQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS 3561

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATV--------TQVCSNPPCETHETGTTNTATTSN 1309
              +    +P TT  +T        +AT         T   + PP     T TT TAT+S 
Sbjct: 3562 STATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSK 3621

Query: 1310 A--GSAQRVCSNPPCETHETGTTHTATTAT-----SNGGTGQ-PEGGQQP--------PA 1353
            A   S+ R  +  P  T  T T  TAT+ T     + G TG  PE    P        P+
Sbjct: 3622 ATSSSSPRTATTLPVLT-STATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPS 3680

Query: 1354 GRPCETH-------QTTSTGTTMSVSVGALLPDAT--SSHRTVESGLEVAAAPSVTPQA- 1403
              P  TH       + T+T  T S+S  +  P  T   +  T  +    A  P+ TP + 
Sbjct: 3681 STPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSST 3740

Query: 1404 -GTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSN-MSSNQDPPPAASDQGEVESTQG 1461
             GT  +   P+       P  +  T ++  AT  T   ++S    P   S +    S+ G
Sbjct: 3741 PGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPG 3800

Query: 1462 DSVNITSSSAITTTVSSTLTRAVTTV---TQSTPVPGPSVPPPEELQVSPGPRQQLPPRQ 1518
             +  + +  +  TT ++T   A+ +    T  T +   + P       +P    +     
Sbjct: 3801 TATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTS 3860

Query: 1519 LLQSASTALMGESAEVLSASQTP------ELPAAVDLSSTGEPSSGQESAGSAVVATVVV 1572
             + + +T     +  V + S TP      ++P       T  PSS   +A +  V     
Sbjct: 3861 TVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTT 3920

Query: 1573 QPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQA 1632
              P    S V   S+P          T T++ T  T       A   ++ Q + T     
Sbjct: 3921 TTPTTRGSTVTPSSIP------GTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPP 3974

Query: 1633 LAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELA 1692
            +         +     +   + T+  +AT       H+          T P  +T    A
Sbjct: 3975 VPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHI----------TEPSTVTSHTPA 4024

Query: 1693 ALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPS-TA 1751
            A     Q         H    T    P+     P           GT  +T    PS T 
Sbjct: 4025 ATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTP-------GHTRGTSRTTATATPSKTR 4077

Query: 1752 TESLAPSNTFVAPQPVVVASPAKLQAA 1778
            T +L PS+   AP   VV +  + Q A
Sbjct: 4078 TSTLLPSSPTSAPITTVVTTGCEPQCA 4104



 Score =  142 bits (359), Expect = 3e-33
 Identities = 342/1437 (23%), Positives = 489/1437 (34%), Gaps = 187/1437 (13%)

Query: 404  ATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPA----PPTTT 459
            +T  T T+ T     SV A P  +P  A     V   T  G T  P ++P     PP   
Sbjct: 3860 STVLTTTTTTTRATGSV-ATPSSTPGTAHTTK-VPTTTTTGFTATPSSSPGTALTPPVWI 3917

Query: 460  TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSL 519
            +    PT  GS+++  +   T     VL  T     TG         S A  +  T TS 
Sbjct: 3918 STTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATG---------SMATPSSSTQTS- 3967

Query: 520  PAGVRMVVPTQSAQGTVIGSS-PQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVK 578
              G     P  +   T  G S P  S      A  +AT  I  ++  T  S     T   
Sbjct: 3968 --GTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAA 4025

Query: 579  TMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKS 638
            T + T  +T  PA      S     +P +    T     GTS ++AT T ++   +    
Sbjct: 4026 TTSTTQHST--PALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLP 4083

Query: 639  GTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSA----LISNLGKVMSVVQTKPVQT 694
             + T A    VVTT           +     +PG S       SN+      V  +P+  
Sbjct: 4084 SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGL 4143

Query: 695  SAVTGQASTG-PVTQIIQT-KGPLPAGTILKLVTSADGKPTTIIT---TTQASGAGTKPT 749
                 QA  G P+ ++ Q  +  L  G + +      GK                G  P+
Sbjct: 4144 EC-RAQAQPGVPLRELGQVVECSLDFGLVCRNREQV-GKFKMCFNYEIRVFCCNYGHCPS 4201

Query: 750  ILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTG 809
                SS +  ++ PGTT I+  +  +A  T++  TG T++P      T I T+  T    
Sbjct: 4202 TPATSSTATPSSTPGTTWILTKLTTTATTTES--TGSTATPSSTPGTTWILTEPST---- 4255

Query: 810  APAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAV 869
                  TA   + TG      +     G P    T   T P       TP +      A+
Sbjct: 4256 ------TATVTVPTGSTATASSTQATAGTPHVSTTA--TTPTVTSSKATPFSSPGTATAL 4307

Query: 870  TTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAI 929
              L    TT   T  T   + S          T+   A    T+ T    S+     T+ 
Sbjct: 4308 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA----TMSTATPSSTPETAHTST 4363

Query: 930  TVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQ 989
             ++   TT  A G + TP+ T  P +  T     T  +G    P    P +    P    
Sbjct: 4364 VLTTTATTTRATGSVATPSST--PGTAHTTKVPTTTTTGFTVTP-SSSPGTARTPPVWIS 4420

Query: 990  PTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
             T T T + S          T+  S+ P  TH T T  T TTT VA  G    P+     
Sbjct: 4421 TTTTPTTSGS----------TVTPSSVPGTTH-TPTVLTTTTTTVAT-GSMATPSSSTQT 4468

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPC 1109
                      V +T    +G  +   S     T  T  T+     T       G S+ P 
Sbjct: 4469 SGTTHTPP--VPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPA 4526

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT- 1168
             T  TGTT  +T A+SS   +  R      + GT      +  +     A  SK++  T 
Sbjct: 4527 AT--TGTTQHSTPALSSPHPS-SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTL 4583

Query: 1169 ---RQTSATSTTMTVMATGAPCS-------AGPLLGPSMAREPGGRSPAFVQLAPLSSKV 1218
                 TSA  TT+        C+       + P+ GPS     GG    +       S +
Sbjct: 4584 LPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS-----GGDFDTY-------SNI 4631

Query: 1219 RLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL 1278
            R +  ++ + P G     +   A  +  V  GE      C SL  G           +  
Sbjct: 4632 RAAGGAVCEQPLG-----LECRAQAQPGVPLGELGQVVEC-SLDFGLVCRNREQVG-KFK 4684

Query: 1279 LCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATS 1338
            +C +  +   C N         T++TA  S         S P      T  T TATT  S
Sbjct: 4685 MCFNYEIRVFCCNYGHCPSTPATSSTAMPS---------STPGTTWILTELTTTATTTAS 4735

Query: 1339 NGGTGQPEG--GQQPP---AGRPCETHQTTSTGTTMSVS--VGALLPDATSSHRTVESGL 1391
             G T  P    G  PP      P  T   TS+  T S S      LP  TS+  T  +  
Sbjct: 4736 TGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTST-ATKSTAT 4794

Query: 1392 EVAAAPSVT-------PQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             V   PS T       P+  T  +A   T    S P        TTHT+T +T+  ++ +
Sbjct: 4795 SVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPE-------TTHTSTVLTTKATTTR 4847

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                A S      ST G           TT + + LT A TT   + P   PS       
Sbjct: 4848 ----ATSSTSTPSSTPG-----------TTWILTELTTAATTTAATGPTATPS------- 4885

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQT------PELPAAVDL--SSTGEPS 1556
              +PG    L       + +TA  G +A   S   T      P   A V +   ST   S
Sbjct: 4886 -STPGTTWIL-TELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS 4943

Query: 1557 SGQESAGSAVVATVVVQP------PPPTQSEVDQLSLPQELMAEAQAGTTTLMVT----- 1605
            S Q +AG+  V+T    P        P+ S     +LP  L + A   T T         
Sbjct: 4944 STQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALP-ALRSTATTPTATSFTAIPSSS 5002

Query: 1606 -GLTPEELAVTAAAEAA-AQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVT 1663
             G T   L+ T    A  + A  +   + +    VL A       TG     S    T  
Sbjct: 5003 LGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAH 5062

Query: 1664 QAELGHLSAEGQEGQATTIP-IVLTQQELAALVQQQQLQEAQAQQQHH--HLPTEALAPA 1720
              ++   +  G     ++ P   LT      +     +  +   +  H   + T      
Sbjct: 5063 TTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMT 5122

Query: 1721 DSLNDPAIESN------CLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVAS 1771
             + N  A  S+       L EL  T  +T A   STAT S  P  T++  +P  +A+
Sbjct: 5123 RATNSTATPSSTLGTTRILTELT-TTATTTAATGSTATLSSTPGTTWILTEPSTIAT 5178



 Score =  141 bits (356), Expect = 6e-33
 Identities = 277/1167 (23%), Positives = 406/1167 (34%), Gaps = 199/1167 (17%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAP------P 456
            P+T AT+++ TP+  P       K    A    +       G T  P + P        P
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTEST------GSTATPSSTPGTTWILTEP 4253

Query: 457  TTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTV 516
            +TT    +PT  GS+ +  +   T G P V        T  TP VT   A+    +P T 
Sbjct: 4254 STTATVTVPT--GSTATASSTQATAGTPHV------STTATTPTVTSSKATPFS-SPGTA 4304

Query: 517  TSLPAGVRMVVPTQSAQG-TVIGSSPQMSGMAALAAAAAATQKIP---PSSAP------T 566
            T+LPA +R    T +A   T I SS   +    L+     T  +    PSS P      T
Sbjct: 4305 TALPA-LRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTST 4363

Query: 567  VLSVPAGTT----IVKTMAVTPGT---------TTLPATVKVASSPVMVSNP----ATRM 609
            VL+  A TT     V T + TPGT         TT   TV  +SSP     P    +T  
Sbjct: 4364 VLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTT 4423

Query: 610  LKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS 669
              T +    T  S    T T  ++T   +   T +      +T   G T T  +  +  +
Sbjct: 4424 TPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTAT 4483

Query: 670  VPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSAD 729
              G S   S+   V      +   TSA +G   T  +T+        PA T     T   
Sbjct: 4484 THGRSLSPSSPHTV------RTAWTSATSGTLGTTHITEPSTGTSHTPAAT-----TGTT 4532

Query: 730  GKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSS 789
               T  +++   S   T+      S  SP TT PG TT       +A  ++   + +  S
Sbjct: 4533 QHSTPALSSPHPSSRTTE------SPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPS 4586

Query: 790  PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG------------ 837
                +PIT + T            +  + P      G       +               
Sbjct: 4587 SPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLE 4646

Query: 838  --APGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLA 895
              A  QPG     VP+G +  V   ++         LV +    V               
Sbjct: 4647 CRAQAQPG-----VPLGELGQVVECSLDF------GLVCRNREQVGKFKMCFNYEIRVFC 4695

Query: 896  GAGGHSTS----ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITM 951
               GH  S    +S A P +T GT   L       T +T +A  TT  + G   TP+ T 
Sbjct: 4696 CNYGHCPSTPATSSTAMPSSTPGTTWIL-------TELTTTA--TTTASTGSTATPSSTP 4746

Query: 952  QPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTL 1011
                 P    ++T+P+          P +  +  T+     T T            T T 
Sbjct: 4747 GTAPPPK---VLTSPATT--------PTATSSKATSSSSPRTATTLPVLTSTATKSTATS 4795

Query: 1012 VCSNPPCETHETGTTNTATTTVVANLGG-HPQPTQVQFVCDRQEAAASLVTSTVGQQNGS 1070
            V   P      TGT    TTT VA +   HP  T             +  TSTV     +
Sbjct: 4796 VTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTP-----------ETTHTSTVLTTKAT 4844

Query: 1071 VVRVCSNPPCETHETGTT---NTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSV 1127
              R  S+    +   GTT      TTA +  A   G +  P  T  T    T  T  ++ 
Sbjct: 4845 TTRATSSTSTPSSTPGTTWILTELTTAATTTAAT-GPTATPSSTPGTTWILTELTTTATT 4903

Query: 1128 GANHQRDARRACAAGTPAVIR-------ISVATGALEAAQGSKSQCQTRQTSATSTTMTV 1180
             A+    A  +   GT  ++        ++V TG+   A  +++   T   S T+TT TV
Sbjct: 4904 TASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 4963

Query: 1181 MATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTA 1240
             ++ A  S+ P    ++   P  RS A             ++P+           A S  
Sbjct: 4964 TSSKATPSSSPGTATAL---PALRSTA-------------TTPT-----------ATSFT 4996

Query: 1241 AMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETG 1300
            A+  SS+G    R+            S T T TA  +   PS+T   V ++       T 
Sbjct: 4997 AIPSSSLGTTWTRL------------SQTTTPTATMSTATPSSTPETVHTS-------TV 5037

Query: 1301 TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH 1360
             T TATT+ A  +    S+ P   H T    T TT  +   +  P     PP   P  T 
Sbjct: 5038 LTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTM 5097

Query: 1361 QTTSTGTTMS-------VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPT 1413
             T  T +T         ++  A +  AT+S  T  S L      +      T   A   T
Sbjct: 5098 STIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGST 5157

Query: 1414 QRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAIT 1473
              + S P       GTT   T   S +++   P  + +       T      +T+ + + 
Sbjct: 5158 ATLSSTP-------GTTWILTE-PSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMP 5209

Query: 1474 TTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            T  +ST+  + T  T  TP   PS  P
Sbjct: 5210 TATASTVPSSSTVGTTRTPAVLPSSLP 5236



 Score =  133 bits (335), Expect = 2e-30
 Identities = 342/1587 (21%), Positives = 525/1587 (33%), Gaps = 284/1587 (17%)

Query: 392  SYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQA 451
            +++L  Q      TA T ++  P+  P   A PPK     A  P               +
Sbjct: 3573 TWILTEQTTAATTTATTGSTAIPSSTPGT-APPPKVLTSTATTPTATSSKAT-------S 3624

Query: 452  APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPA-VLKVTG--PQATTGTPLVTMRPASQ 508
            + +P T TT+ VL +    S    TA     +P+  L  TG  P+ TT TP+ TM     
Sbjct: 3625 SSSPRTATTLPVLTSTATKS----TATSFTPIPSFTLGTTGTLPEQTT-TPMATMSTIHP 3679

Query: 509  AGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTV 567
            +     T TS     +      ++  +   S+P  +  +  L  AA  T    P++ P+ 
Sbjct: 3680 SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPS- 3738

Query: 568  LSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT 627
             S P GTT + T   T  T T+P T   A++    +   T  + T+ A   T +SS    
Sbjct: 3739 -STP-GTTWILTEPSTTATVTVP-TGSTATASSTRATAGTLKVLTSTATTPTVISSRATP 3795

Query: 628  STRP--IITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMS 685
            S+ P     +    +      A  VT +      T     S  + P  +   +       
Sbjct: 3796 SSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPE 3855

Query: 686  VVQTKPVQTSAVTGQASTGPVTQIIQTKGP-----LPAGTILKLVTSADGKPTTIITTTQ 740
             V T  V T+  T   +TG V     T G      +P  T      +    P T +T   
Sbjct: 3856 TVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPV 3915

Query: 741  ASGAGTKPTILGISSVSPSTTKPGTT-------TIIKTIPMSAIITQAGAT---GVTSSP 790
                 T PT  G S+V+PS+  PGTT       T   T+   ++ T + +T   G T +P
Sbjct: 3916 WISTTTTPTTRG-STVTPSSI-PGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTP 3973

Query: 791  GIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVP 850
             +  P T  TT   +    +P  + TA     +G    G T +       +P T+    P
Sbjct: 3974 PV--PNTTATTHGRSLPPSSPHTVRTAWTSATSGI--LGTTHIT------EPSTVTSHTP 4023

Query: 851  MGGVRLVTPVT--VSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASL-- 906
                      T  +S+  P+  T     + G TT G   GT  T+       + +++L  
Sbjct: 4024 AATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLP 4083

Query: 907  ----ATPITTLGTIAT-----------LSSQVINPTAITVSAAQTTLTAAGGLTTPTITM 951
                + PITT+ T               S  +  P+            A G +    + +
Sbjct: 4084 SSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGL 4143

Query: 952  Q---------PVSQPTQVTLITAPSGV---------EAQPVHDLPVSILAS-----PTTE 988
            +         P+ +  QV   +   G+         + +   +  + +        P+T 
Sbjct: 4144 ECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTP 4203

Query: 989  QPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQ-VQ 1047
              ++T T + +      PGT  ++          T  T TATTT        P  T    
Sbjct: 4204 ATSSTATPSST------PGTTWIL----------TKLTTTATTTESTGSTATPSSTPGTT 4247

Query: 1048 FVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNP 1107
            ++       A++   T      S  +  +  P     T TT T T++ +      G +  
Sbjct: 4248 WILTEPSTTATVTVPTGSTATASSTQATAGTP-HVSTTATTPTVTSSKATPFSSPGTATA 4306

Query: 1108 PCETHETGTTNTATT----AMSSVGANHQRDARR---------ACAAGTPAVIRISVA-- 1152
                  T TT TAT+      SS+G    R ++          A  + TP     S    
Sbjct: 4307 LPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLT 4366

Query: 1153 -TGALEAAQGS----KSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPA 1207
             T     A GS     S   T  T+   TT T   T  P S+     P  AR P    P 
Sbjct: 4367 TTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSS-----PGTARTP----PV 4417

Query: 1208 FVQLA--PLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGS 1265
            ++     P +S   ++  S+   P   H+  V T   T  + G+    MA    S Q   
Sbjct: 4418 WISTTTTPTTSGSTVTPSSV---PGTTHTPTVLTTTTTTVATGS----MATPSSSTQTSG 4470

Query: 1266 PSTTVTVTALEALLCPSATVT-QVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCET 1324
             + T  V        P+ T T    S  P   H   T  T+ TS       + + P   T
Sbjct: 4471 TTHTPPV--------PNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHI-TEPSTGT 4521

Query: 1325 HETGTTHTATTATSNGGTGQPEGG----QQPPA------GRPCETHQTTSTGTTMSVSVG 1374
              T    T TT  S      P       + PP+      G    T +TT+T T       
Sbjct: 4522 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS 4581

Query: 1375 ALLPDATSSH---RTVESGLEVAAAPS----------------------VTPQAGTALLA 1409
             LLP + +S      V +G E   A S                      +    G     
Sbjct: 4582 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ 4641

Query: 1410 PFPTQ-RVCSNPPCETHETGTTHTATT----VTSN--------MSSNQDPPPAASDQGEV 1456
            P   + R  + P     E G     +     V  N        M  N +      + G  
Sbjct: 4642 PLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC 4701

Query: 1457 ESTQGDSVNITSSSA-----ITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPR 1511
             ST   S     SS      I T +++T T   +T + +TP   P   PP ++  SP   
Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATT 4761

Query: 1512 QQLPPRQLLQSAS-------TALMGESAEVLSASQTP--------------ELPAAVDLS 1550
                  +   S+S         L   + +  + S TP              +    V   
Sbjct: 4762 PTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATM 4821

Query: 1551 STGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE--LMAEAQAGTTTLMVTGLT 1608
            ST  PSS  E+  ++ V T        T S     S P    ++ E     TT   TG T
Sbjct: 4822 STIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPT 4881

Query: 1609 P------------EELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTS 1656
                          EL  TA   A+  + AT  +       + + +  A + T     T+
Sbjct: 4882 ATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATV-TVPTGSTA 4940

Query: 1657 EAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEA 1716
             A++T   A   H+S         T P V + +                        T +
Sbjct: 4941 TASSTQATAGTPHVST------TATTPTVTSSK-----------------------ATPS 4971

Query: 1717 LAPADSLNDPAIESNCLNELAGT---VPS-----TVALLPSTATESLAPSNTFVAPQPVV 1768
             +P  +   PA+ S      A +   +PS     T   L  T T +   S    +  P  
Sbjct: 4972 SSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPET 5031

Query: 1769 VASPAKLQAAATLTEVANGIESLGVKP 1795
            V +   L A AT T     + +    P
Sbjct: 5032 VHTSTVLTATATTTGATGSVATPSSTP 5058



 Score =  130 bits (328), Expect = 1e-29
 Identities = 242/1110 (21%), Positives = 389/1110 (35%), Gaps = 126/1110 (11%)

Query: 590  PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQV 649
            P+T   +S+ +  S P T  + T      T+  S  +T+T P  T   +  +T       
Sbjct: 3053 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTAT-PSSTPGTTWILTEPSTTAT 3111

Query: 650  VTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI 709
            VT   G  T T +  ++    P           V +   T  V +S  T  +S G  T +
Sbjct: 3112 VTVPTGS-TATASSTQATAGTP----------HVSTTATTPTVTSSKATPFSSPGTATAL 3160

Query: 710  IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTII 769
               +      T     TS    P++ + TT    + T      +S+ +PS+T     T+ 
Sbjct: 3161 PALRSTATTPT----ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPE---TVH 3213

Query: 770  KTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQ-- 827
             +  ++   T  GATG  ++P   +P T  TTKV+T+ T       TA P  + G  +  
Sbjct: 3214 TSTVLTTTATTTGATGSVATPS-STPGTAHTTKVLTTTTTG----FTATPSSSPGTARTL 3268

Query: 828  ----QGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883
                   T    +G+   P +I  T     V   T  TV+    A  +   + T+G T  
Sbjct: 3269 PVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQ-TSGTTHT 3327

Query: 884  GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG- 942
              V  T +T+      H  S S ++P T      + +S  +  T IT  +  T+ T A  
Sbjct: 3328 PPVPNTTATT------HGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 3381

Query: 943  -GLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQ 1001
             G T  +        P+  T  + PS     P H    S   +  T   T T T+  S  
Sbjct: 3382 TGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSP 3441

Query: 1002 GDVQPGTVTLVCSNPPCETHET------------GTTNTATTTVVANLGGHPQPTQVQFV 1049
                  TV  +   P C   E             G  +T +    A      QP  ++  
Sbjct: 3442 TSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECR 3501

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPP----------------CETHETGTTNTATT 1093
               Q          V + +     VC N                  C  +    +  AT+
Sbjct: 3502 AQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATS 3561

Query: 1094 ATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVAT 1153
            +T+  +   G +    E   T  T TATT  +++ ++           GT    ++  +T
Sbjct: 3562 STATPSSTPGTTWILTE-QTTAATTTATTGSTAIPSS---------TPGTAPPPKVLTST 3611

Query: 1154 GALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAP 1213
                 A  SK+   +  +  T+TT+ V+ + A  S      P  +   G       Q   
Sbjct: 3612 ATTPTATSSKATSSS--SPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTT 3669

Query: 1214 LSSKVRLSSPSIKDLPAGRHSHAVST--AAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
              + +    PS    P   H+  V T  A  TR++     P   P    +     +   T
Sbjct: 3670 PMATMSTIHPS--STPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATT 3727

Query: 1272 VTALEALLCPSAT--VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGT 1329
              A      PS+T   T + + P   T  T T  T +T+ A S +               
Sbjct: 3728 TAATGPTATPSSTPGTTWILTEP--STTATVTVPTGSTATASSTRATAGTLKV------L 3779

Query: 1330 THTATTATSNGGTGQPEGGQQPPAGRPC-ETHQTTSTGTTMSVSVGALLPDATS--SHRT 1386
            T TATT T       P          P   +  TT T T+++    + L  A +  S  T
Sbjct: 3780 TSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTT 3839

Query: 1387 VESGLEVAAAPSVTPQA---GTALLAPFPTQRVCSNPPCETHETGTTHTA---TTVTSNM 1440
              +     A PS TP+     T L     T R   +    +   GT HT    TT T+  
Sbjct: 3840 TPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 3899

Query: 1441 SSNQDP-------PPAASDQGEVESTQGDSVNITS-------SSAITTTVSSTLTRAVTT 1486
            ++           PP         +T+G +V  +S       ++ +TTT ++  T ++ T
Sbjct: 3900 TATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMAT 3959

Query: 1487 VTQSTPVPGPSVPPPEELQVSPGPRQQLPP------RQLLQSASTALMGESAEVLSASQT 1540
             + ST   G +  PP     +    + LPP      R    SA++ ++G +     ++ T
Sbjct: 3960 PSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVT 4019

Query: 1541 PELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP--PTQSEVDQLSLPQELMAEAQAG 1598
               PAA   +ST + S+   S+      T    P P   T       S        ++  
Sbjct: 4020 SHTPAAT--TSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTR 4077

Query: 1599 TTTLMVTGLTPEELAVTAAAEAAAQAAATE 1628
            T+TL+ +  T   +          Q A +E
Sbjct: 4078 TSTLLPSSPTSAPITTVVTTGCEPQCAWSE 4107



 Score =  128 bits (322), Expect = 5e-29
 Identities = 296/1306 (22%), Positives = 433/1306 (33%), Gaps = 290/1306 (22%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            P  ++  T   P+P  + P +   +    A A   +  T    TLLP +  + P TT + 
Sbjct: 2893 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS---TLLPSSPTSAPITTVVT 2949

Query: 463  V-----------------LPTVPGSSISVPTAARTQGVPAVLKVTG----PQATTGTPL- 500
            +                 +P   G      +  R  G     +  G     QA  G PL 
Sbjct: 2950 MGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLR 3009

Query: 501  -------------VTMRPASQAGKAPVTVT--------------SLPAGVRMVVPTQS-- 531
                         +  R   Q GK  +                 S PA     +P+ +  
Sbjct: 3010 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPG 3069

Query: 532  -----AQGTVIGSSPQMSGMAALAAAAAATQKI--PPSSAPTVLSVPAGTTIVKTMAVTP 584
                  + T   ++ + +G  A  ++   T  I   PS+  TV +VP G+T   T + T 
Sbjct: 3070 TTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV-TVPTGSTA--TASSTQ 3126

Query: 585  GTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVA 644
             T   P     A++P + S+ AT       A    ++ S   T T    T   S ++   
Sbjct: 3127 ATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 3186

Query: 645  QQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG 704
                  TT       T T    P S P               V T  V T+  T   +TG
Sbjct: 3187 WTRLSQTTTPTATMSTAT----PSSTP-------------ETVHTSTVLTTTATTTGATG 3229

Query: 705  PVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPG 764
             V     T G   A T   L T+     TT  T T +S  GT  T+    S + + T  G
Sbjct: 3230 SVATPSSTPGT--AHTTKVLTTT-----TTGFTATPSSSPGTARTLPVWISTTTTPTTRG 3282

Query: 765  TTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATG 824
            +T    +IP           G T +P      T++TT   T  TG+ A   ++     T 
Sbjct: 3283 STVTPSSIP-----------GTTHTP------TVLTTTTTTVATGSMATPSSSTQTSGTT 3325

Query: 825  HGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLV--VKGTTGVTT 882
            H             P  P T   T      R ++P +   V+ A T+      GTT +T 
Sbjct: 3326 H------------TPPVPNTTATTHG----RSLSPSSPHTVRTAWTSATSGTLGTTHITE 3369

Query: 883  LGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG 942
              T T     +  G   HST A L++P  +  T  +  S        T + ++TT TA  
Sbjct: 3370 PSTGTSHTPAATTGTTQHSTPA-LSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATP 3428

Query: 943  GLTTPTITM--QPVSQP--TQVTL-----------------ITAPSGVEAQPVHDLPVSI 981
              T  +  +   P S P  T VT+                 +  PSG +     ++  + 
Sbjct: 3429 SKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAA- 3487

Query: 982  LASPTTEQPTAT---------VTIADSGQGDVQPGTVTLVCSNPP-------CETHETGT 1025
                  EQP            V + + GQ         LVC N         C  +E   
Sbjct: 3488 -GGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRV 3546

Query: 1026 --------TNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSN 1077
                     +T  T+  A     P  T   ++   Q  AA+   +T      S     + 
Sbjct: 3547 FCCNYGHCPSTPATSSTATPSSTPGTT---WILTEQTTAATTTATTGSTAIPSSTPGTAP 3603

Query: 1078 PPCETHETGTTNTATTA-----------------TSNMAGQHGCSNPPCETHETGTTNT- 1119
            PP     T TT TAT++                 TS        S  P  +   GTT T 
Sbjct: 3604 PPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTL 3663

Query: 1120 ---ATTAMSSVGANHQRDARRACAAGTPAVIRIS-VATGALEAAQGSKSQCQTRQTSATS 1175
                TT M+++   H         + TP     S V T      + + S      T  T+
Sbjct: 3664 PEQTTTPMATMSTIHP--------SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3715

Query: 1176 TTMTVMATGAPCSA--GPLLGPS-------MAREPGGRSPAFVQLAPLS--SKVRLSSPS 1224
              +T + T A  +A  GP   PS       +  EP   +   V     +  S  R ++ +
Sbjct: 3716 WILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGT 3775

Query: 1225 IKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTV----------TA 1274
            +K L +   +  V ++  T SS   G     P   S      +T+VT           T 
Sbjct: 3776 LKVLTSTATTPTVISSRATPSS-SPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTR 3834

Query: 1275 LEALLCPSATVTQVCSNPPCETHETGT--TNTATTSNAGSAQRVCSNPPCETHETGTTHT 1332
            L     P+AT++    +   ET  T T  T T TT+ A  +    S+ P   H T    T
Sbjct: 3835 LSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTT 3894

Query: 1333 ATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDA---TSSHRTVES 1389
             TT  +   +  P     PP      T  TT   T    S+      A   T++  TV +
Sbjct: 3895 TTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVAT 3954

Query: 1390 GLEVAAAPSVTPQAGTALLAPFP----TQRVCSNPPCETHET------------GTTH-- 1431
            G  +A   S T  +GT    P P    T    S PP   H              GTTH  
Sbjct: 3955 G-SMATPSSSTQTSGTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHIT 4013

Query: 1432 ----------TATTVT-------------SNMSSNQDPPPAASDQGEVESTQGDSVNITS 1468
                       ATT T             S+ ++   P P  +  G    T   +   T 
Sbjct: 4014 EPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATP 4073

Query: 1469 SSAITTTV------SSTLTRAVTT-----------VTQSTPVPGPS 1497
            S   T+T+      S+ +T  VTT           +  S P+PGPS
Sbjct: 4074 SKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS 4119



 Score =  121 bits (304), Expect = 6e-27
 Identities = 254/1110 (22%), Positives = 391/1110 (35%), Gaps = 117/1110 (10%)

Query: 561  PSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTS 620
            PS+  T  +    +T   T  +T  TTT   T    S+    S P T  + T  +   T 
Sbjct: 4200 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 4259

Query: 621  V----SSATNTSTRPII-TVHKSGTVTVAQQAQVVTTVVG--GVTKTITLVKSPISVPGG 673
                 S+AT +ST+    T H S T T         T     G    +  ++S  + P  
Sbjct: 4260 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTA 4319

Query: 674  SALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPT 733
            ++  +     +    T+  QT+  T   ST   +   +T       T     T A G   
Sbjct: 4320 TSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVA 4379

Query: 734  TIITTTQASGAGTKPTILGISSVSPSTTKPGTT-TIIKTIPMSAIITQAGATGVTSS-PG 791
            T  +T   +     PT          ++ PGT  T    I  +   T +G+T   SS PG
Sbjct: 4380 TPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 4439

Query: 792  IKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                 T++TT   T  TG+ A   ++     T H             P  P T   T   
Sbjct: 4440 TTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTH------------TPPVPNTTATTHG- 4486

Query: 852  GGVRLVTPVTVSAVKPAVTTLV--VKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATP 909
               R ++P +   V+ A T+      GTT +T   T T     +  G   HST A L++P
Sbjct: 4487 ---RSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPA-LSSP 4542

Query: 910  ITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITA-PSG 968
              +  T  +  S        T + ++TT TA    T  T T+ P S PT   + T   +G
Sbjct: 4543 HPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTR-TSTLLP-SSPTSAPITTVVTTG 4600

Query: 969  VEAQPVHD--LPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVC---SNPPCETHET 1023
             E Q      L  S      +     T +   +  G V    + L C   + P     E 
Sbjct: 4601 CEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGEL 4660

Query: 1024 GTTNTATTTVVANLGGHPQPTQVQ---------FVCDRQEAAASLVTSTVGQQNGSVVRV 1074
            G     +           Q  + +         F C+     ++  TS+    + +    
Sbjct: 4661 GQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPGTT 4720

Query: 1075 CSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRD 1134
                   T  T T +T +TAT +     G + PP       TT TAT++ ++  ++ +  
Sbjct: 4721 WILTELTTTATTTASTGSTATPSSTP--GTAPPPKVLTSPATTPTATSSKATSSSSPRT- 4777

Query: 1135 ARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQT--SATSTTMTVMATGAPCSAGPL 1192
                 A   P +   +  + A        S   T  T    T+T +  M+T  P S    
Sbjct: 4778 -----ATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPET 4832

Query: 1193 LGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEP 1252
               S        + A    A  S+    S+P    +     + A +TAA   ++  +  P
Sbjct: 4833 THTSTVLT----TKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 4888

Query: 1253 RMAPVCESLQGGSPSTTVTVTALE-ALLCPSAT--VTQVCSNPPCETHETGTTNTATTSN 1309
                +   L     +TT T TA   +   PS+T   T + + P   T  T T  T +T+ 
Sbjct: 4889 GTTWILTEL-----TTTATTTASTGSTATPSSTPGTTWILTEP--STTATVTVPTGSTAT 4941

Query: 1310 AGSAQRVCSNPPCETHETGTTHTATTAT--SNGGTGQPEGGQQPPAGRPCETHQT----T 1363
            A S Q     P   T  T  T T++ AT  S+ GT       +  A  P  T  T    +
Sbjct: 4942 ASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSS 5001

Query: 1364 STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQA---GTALLAPFPTQRVCSNP 1420
            S GTT +       P AT S           A PS TP+     T L A   T     + 
Sbjct: 5002 SLGTTWTRLSQTTTPTATMS----------TATPSSTPETVHTSTVLTATATTTGATGSV 5051

Query: 1421 PCETHETGTTHTA---TTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVS 1477
               +   GT HT    TT T+  ++     P  +      +       I +SS   TT +
Sbjct: 5052 ATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETTHT 5111

Query: 1478 STLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSA 1537
            ST+     T+T++T     +  P   L  +     ++       + +TA  G +A + S 
Sbjct: 5112 STVLTTTATMTRAT---NSTATPSSTLGTT-----RILTELTTTATTTAATGSTATLSST 5163

Query: 1538 SQTPEL--------PAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLS--- 1586
              T  +           V   ST   SS   +A +  V T +   P  T S V   S   
Sbjct: 5164 PGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMATMPTATASTVPSSSTVG 5223

Query: 1587 -------LPQELMAEAQAGTTTLMVTGLTP 1609
                   LP  L   + +  ++ ++T L P
Sbjct: 5224 TTRTPAVLPSSLPTFSVSTVSSSVLTTLRP 5253



 Score =  117 bits (294), Expect = 9e-26
 Identities = 367/1692 (21%), Positives = 552/1692 (32%), Gaps = 339/1692 (20%)

Query: 325  HCAVAINTRLYIWSGRDGYRKAWNNQV---CCKDLWYLETEKPPPPARVQLVRANTNSLE 381
            HC V        W     ++  +N ++   CC D         PPP   +L  A T + +
Sbjct: 2260 HCDVHFGLVCRNWEQEGVFKMCYNYRIRVLCCSDDHCRGRATTPPPT-TELETATTTTTQ 2318

Query: 382  V-------------------SWGAVATADSYLLQLQKYDIPATAATA--TSPTPNPVPSV 420
                                S  AV T    L   +      TA T   T+P  +  P+V
Sbjct: 2319 ALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTV 2378

Query: 421  PANPPKSPAPAAAAPAVQPLTQVGITLLPQAAP--APPTTTTIQVLPTVPGSSISVPTAA 478
            P     +    +A P       +G T  P   P  AP T  T +  PT   S+ S     
Sbjct: 2379 PGVATSTLPTRSALPGTTG--SLG-TWRPSQPPTLAPTTMATSRARPTGTASTASKEPLT 2435

Query: 479  RTQGVPAVLKVTGPQATTGTPLV--TMRPASQAGKAPVTVTSLPA-----GVRMVVPTQS 531
             +       +++  QA T TP    TM P +    +  T    P         +  PT  
Sbjct: 2436 TSLAPTLTSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSG 2495

Query: 532  AQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTT--- 588
              G  + +   +         A  + +    + P V     G  +  T ++  G T    
Sbjct: 2496 VAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVL--TCSLETGLTCKNE 2553

Query: 589  ------------------------LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSA 624
                                     P+T   +S+    S P T  + T      T+ +S 
Sbjct: 2554 DQTGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWILTKPTTTATTTAST 2613

Query: 625  TNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKS-PISVPGGSALISNLGKV 683
             +T+T        + T+  A   +V+TT     T T+T  K+ P S PG +  +  L   
Sbjct: 2614 GSTAT-------PTSTLRTAPPPKVLTTTA--TTPTVTSSKATPSSSPGTATALPALRST 2664

Query: 684  ----------------MSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTS 727
                            +    T+  QT+  T   ST   +   +T       T     T 
Sbjct: 2665 ATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTG 2724

Query: 728  ADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTT-TIIKTIPMSAIITQAGATGV 786
            A G   T  +T   +     PT       +  ++ PGT  T    I  +   T  G+T  
Sbjct: 2725 ATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVT 2784

Query: 787  TSS-PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTI 845
             SS PG     T++TT   T  TG+ A   ++     T H             P  P T+
Sbjct: 2785 PSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTH------------TPPVPNTM 2832

Query: 846  LRTVPMGGVRLVTPVTVSAVKPAVT--TLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTS 903
              T      R + P +   V+ A T  T  + GTT +T   TVT     +  G   HST 
Sbjct: 2833 ATT----HGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTP 2888

Query: 904  ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLI 963
            A L++P  +  T  +  S        T + ++TT TA     T T T+ P S PT   + 
Sbjct: 2889 A-LSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPS-KTRTSTLLP-SSPTSAPIT 2945

Query: 964  TAPS-GVEAQPVHD--LPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVC---SNPP 1017
            T  + G E Q      L  S      +     T +   +  G V    + L C   + P 
Sbjct: 2946 TVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPG 3005

Query: 1018 CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSN 1077
                E G     +                  VC  +E             N  +   C N
Sbjct: 3006 VPLRELGQVVECS-------------LDFGLVCRNREQVGKFKMCF----NYEIRVFCCN 3048

Query: 1078 PPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARR 1137
                 H   T  T++TA  +       S P      T  T TATT  S+        A  
Sbjct: 3049 ---YGHCPSTPATSSTAMPS-------STPGTTWILTELTTTATTTESTGST-----ATP 3093

Query: 1138 ACAAGTPAVI-------RISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAG 1190
            +   GT  ++        ++V TG+   A  +++   T   S T+TT TV ++     A 
Sbjct: 3094 SSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSS----KAT 3149

Query: 1191 PLLGPSMARE-PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGA 1249
            P   P  A   P  RS A             ++P+           A S  A+  SS+G 
Sbjct: 3150 PFSSPGTATALPALRSTA-------------TTPT-----------ATSFTAIPSSSLGT 3185

Query: 1250 GEPRMAPV---CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTA- 1305
               R++       ++   +PS+T        +L  +AT T    +    +   GT +T  
Sbjct: 3186 TWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTK 3245

Query: 1306 --TTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH-QT 1362
              TT+  G      S+P       GT  T     S   T    G    P+  P  TH  T
Sbjct: 3246 VLTTTTTGFTATPSSSP-------GTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPT 3298

Query: 1363 TSTGTTMSVSVGALLPDATSSHRTVESG-LEVAAAPSVTPQAGTALLAPFPTQRV----- 1416
              T TT +V+ G++   AT S  T  SG       P+ T       L+P     V     
Sbjct: 3299 VLTTTTTTVATGSM---ATPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWT 3355

Query: 1417 --CSNPPCETH----ETGTTHT--ATTVT-------------SNMSSNQDPPPAASDQGE 1455
               S     TH     TGT+HT  ATT T             S+ ++   P P  +  G 
Sbjct: 3356 SATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGH 3415

Query: 1456 VESTQGDSVNITSSSAITTTV--SSTLTRAVTTVT---------------QSTPVPGPS- 1497
              +T   +   T S   T+T+  SS  +  +TTV                 S P+PGPS 
Sbjct: 3416 TRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSG 3475

Query: 1498 ----------------VPPPEELQVSPGPRQQLPPRQLLQSASTAL-----------MGE 1530
                               P  L+     +  +P R+L Q    +L           +G+
Sbjct: 3476 GDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGK 3535

Query: 1531 --------------------SAEVLSASQTP------------ELPAAVDLSSTGE---P 1555
                                S    S++ TP            +  AA   ++TG    P
Sbjct: 3536 FKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIP 3595

Query: 1556 SSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE------LMAEAQAGTT--------- 1600
            SS   +A    V T     P  T S+    S P+       L + A   T          
Sbjct: 3596 SSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSF 3655

Query: 1601 TLMVTGLTPEELAVTAAAEAAAQAAATEE----AQALAIQAVLQAAQQAVMGTGEPMDTS 1656
            TL  TG  PE+     A  +    ++T E    +  L  +A    A  ++        T+
Sbjct: 3656 TLGTTGTLPEQTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3715

Query: 1657 EAAATVTQAELGHLSAEGQEGQATTIP---IVLTQQELAALVQQQQLQEAQAQQQHHHLP 1713
                 +T A     +A G     ++ P    +LT+    A V       A A        
Sbjct: 3716 WILTELTTAAT-TTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAG 3774

Query: 1714 TEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASPA 1773
            T  +  + +     I S        + P T   LP+  + +  P+ T V   P      A
Sbjct: 3775 TLKVLTSTATTPTVISSRA---TPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTA 3831

Query: 1774 KLQAAATLTEVA 1785
              + + T T  A
Sbjct: 3832 WTRLSQTTTPTA 3843



 Score =  109 bits (273), Expect = 2e-23
 Identities = 174/766 (22%), Positives = 269/766 (35%), Gaps = 120/766 (15%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            P  ++  T   P+P  + P +   +    A A   +  T    TLLP +  + P TT + 
Sbjct: 4542 PHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS---TLLPSSPTSAPITTVVT 4598

Query: 463  V-----------------LPTVPGSSISVPTAARTQGVPAVLKVTG----PQATTGTPL- 500
                              +P   G      +  R  G     +  G     QA  G PL 
Sbjct: 4599 TGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLG 4658

Query: 501  -------------VTMRPASQAGKAPVTVT--------------SLPAGVRMVVPTQSAQ 533
                         +  R   Q GK  +                 S PA     +P+ +  
Sbjct: 4659 ELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSSTPG 4718

Query: 534  GTVIGSSPQMSGMAALAAAAAATQKIPPSSAPT--VLSVPAGTTIVKTMAVTPGTTTLPA 591
             T I +    +     +  + AT    P +AP   VL+ PA T    +   T  ++   A
Sbjct: 4719 TTWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTA 4778

Query: 592  TVKVASSPVMVSNPATRMLKTAAAQVGTS--VSSATNTSTRPIITVHKSGTVTVAQQAQV 649
            T     +     + AT +    ++ +GT+  +   T T    + T+H S T      + V
Sbjct: 4779 TTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTV 4838

Query: 650  VTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI 709
            +TT     T+  +   +P S PG + +++ L             T+A T  A+TGP    
Sbjct: 4839 LTTKAT-TTRATSSTSTPSSTPGTTWILTEL-------------TTAATTTAATGPTATP 4884

Query: 710  IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTT----KPGT 765
              T G     T L          TT  TTT ++G+   P      S +P TT    +P T
Sbjct: 4885 SSTPGTTWILTEL----------TTTATTTASTGSTATP------SSTPGTTWILTEPST 4928

Query: 766  TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAK---IITAVPKIA 822
            T  + T+P  +  T +       +P +    T  TT  +TS    P+      TA+P + 
Sbjct: 4929 TATV-TVPTGSTATASSTQATAGTPHVS---TTATTPTVTSSKATPSSSPGTATALPAL- 4983

Query: 823  TGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPV-TVSAVKPAVTTLVVKGTTGVT 881
                +   T          P + L T      +  TP  T+S   P+ T   V  +T +T
Sbjct: 4984 ----RSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLT 5039

Query: 882  TLGTVTGTVSTSLAGAGGHSTSASLATPITTL-GTIATLSSQ----VINPTAITVSAAQT 936
               T TG   +    +    T+ +   P TT  G  AT SS     +  PT   +S   T
Sbjct: 5040 ATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMST 5099

Query: 937  TLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTI 996
              T++   TT T T+      T    +T  +   A P   L  + + +  T   T T   
Sbjct: 5100 IHTSSTPETTHTSTVL-----TTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAAT 5154

Query: 997  ADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAA 1056
              +      PGT  ++       T    T +TAT +  + LG    P  V  +     A 
Sbjct: 5155 GSTATLSSTPGTTWILTEPSTIATVMVPTGSTATAS--STLGTAHTPKVVTTMATMPTAT 5212

Query: 1057 ASLV--TSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAG 1100
            AS V  +STVG      V   S P   T    T +++   T    G
Sbjct: 5213 ASTVPSSSTVGTTRTPAVLPSSLP---TFSVSTVSSSVLTTLRPTG 5255



 Score =  106 bits (265), Expect = 2e-22
 Identities = 169/665 (25%), Positives = 243/665 (36%), Gaps = 106/665 (15%)

Query: 590  PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQV 649
            P+T   +S+ +  S P T  + T      T+ +S  +T+T        S T   A   +V
Sbjct: 4702 PSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTAT-------PSSTPGTAPPPKV 4754

Query: 650  VTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI 709
            +T              SP + P  ++  +          T PV TS  T   +T  VT I
Sbjct: 4755 LT--------------SPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATS-VTPI 4799

Query: 710  ----IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP--TILGISSVSPSTTKP 763
                + T G LP  T   + T +   P++   TT  S   T    T    SS S  ++ P
Sbjct: 4800 PSSTLGTTGTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTP 4859

Query: 764  GTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIAT 823
            GTT I+  +  +A  T   ATG T++P      T I T++ T+ T   +   TA P    
Sbjct: 4860 GTTWILTELTTAA--TTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPS--- 4914

Query: 824  GHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883
                 G T ++ +  P    T+  TVP G     +    +A  P V+T          T 
Sbjct: 4915 --STPGTTWILTE--PSTTATV--TVPTGSTATASSTQATAGTPHVST--------TATT 4960

Query: 884  GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGG 943
             TVT + +T        S+S   AT +  L + AT +    + TAI  S+  TT T    
Sbjct: 4961 PTVTSSKATP-------SSSPGTATALPALRSTAT-TPTATSFTAIPSSSLGTTWTRLSQ 5012

Query: 944  LTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGD 1003
             TTPT TM            TA      + VH   V + A+ TT   T +V    S    
Sbjct: 5013 TTTPTATMS-----------TATPSSTPETVHTSTV-LTATATTTGATGSVATPSS---- 5056

Query: 1004 VQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTST 1063
              PGT            H T    T TT   A     P               A    +T
Sbjct: 5057 -TPGT-----------AHTTKVPTTTTTGFTATPSSSP-------------GTALTPPTT 5091

Query: 1064 VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
                  S +   S P     ET  T+T  T T+ M      +  P  T  T    T  T 
Sbjct: 5092 TPMSTMSTIHTSSTP-----ETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTT 5146

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQC-QTRQTSATSTTMTVMA 1182
             ++  A     A  +   GT  ++        +    GS +    T  T+ T   +T MA
Sbjct: 5147 TATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMA 5206

Query: 1183 TGAPCSAGPLLGPSMAREPGGRSPAFVQLA-PLSSKVRLSSPSIKDL-PAGRHSHAVSTA 1240
            T    +A  +  PS +     R+PA +  + P  S   +SS  +  L P G  S   ST 
Sbjct: 5207 TMPTATASTV--PSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFPSSHFSTP 5264

Query: 1241 AMTRS 1245
               R+
Sbjct: 5265 CFCRA 5269



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 139/580 (23%), Positives = 211/580 (36%), Gaps = 63/580 (10%)

Query: 366  PPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPAN-- 423
            PP +V    A T +   S    +++      L      AT +TATS TP P  ++     
Sbjct: 4750 PPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT 4809

Query: 424  -PPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQG 482
             P ++  P A    + P            +  P TT T  VL T   ++ +  + +    
Sbjct: 4810 LPEQTTTPVATMSTIHP------------SSTPETTHTSTVLTTKATTTRATSSTSTPSS 4857

Query: 483  VPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQ 542
             P    +     T  T      P +     P T   L         T S   T   SS  
Sbjct: 4858 TPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTP 4917

Query: 543  MSGMAALAAAAAATQKIPPSSAPTVLS--VPAGTTIVKTMAVTPGTTTLPATVKVASSP- 599
             +       +  AT  +P  S  T  S    AGT  V T A TP  T+  AT   +SSP 
Sbjct: 4918 GTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT--PSSSPG 4975

Query: 600  VMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTK 659
               + PA R   TA     TS ++  ++S     T     T   A  +    +       
Sbjct: 4976 TATALPALR--STATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVH 5033

Query: 660  TITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTG---QASTGPVTQIIQTKGPL 716
            T T++ +  +  G +  ++          T  V T+  TG     S+ P T +       
Sbjct: 5034 TSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPT-TT 5092

Query: 717  PAGTILKLVTSADGKPT---TIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIP 773
            P  T+  + TS+  + T   T++TTT      T       S+ +PS+T  GTT I+  + 
Sbjct: 5093 PMSTMSTIHTSSTPETTHTSTVLTTTATMTRATN------STATPSSTL-GTTRILTELT 5145

Query: 774  MSAIITQA-GATG-VTSSPG----IKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQ 827
             +A  T A G+T  ++S+PG    +  P TI T  V T  T       TA   + T H  
Sbjct: 5146 TTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTA------TASSTLGTAHTP 5199

Query: 828  QGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVT 887
            + VT +        P     TVP          + S V    T  V+  +    ++ TV+
Sbjct: 5200 KVVTTMAT-----MPTATASTVP----------SSSTVGTTRTPAVLPSSLPTFSVSTVS 5244

Query: 888  GTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPT 927
             +V T+L   G  S+  S        G   +    + N T
Sbjct: 5245 SSVLTTLRPTGFPSSHFSTPCFCRAFGQFFSPGEVIYNKT 5284



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 55/248 (22%), Positives = 90/248 (36%), Gaps = 26/248 (10%)

Query: 365  PPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANP 424
            P       V   T +   + G+VAT  S         +P T  T  + TP+         
Sbjct: 5029 PETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPS--------- 5079

Query: 425  PKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP 484
              SP  A   P   P++ +             T+T +    T+  ++ S  T + T G  
Sbjct: 5080 -SSPGTALTPPTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGTT 5138

Query: 485  AVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMS 544
             +L          T L T    + A  +  T++S P G   ++   S   TV+      +
Sbjct: 5139 RIL----------TELTTTATTTAATGSTATLSSTP-GTTWILTEPSTIATVM----VPT 5183

Query: 545  GMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSN 604
            G  A A++   T    P    T+ ++P  T      + T GTT  PA +  +     VS 
Sbjct: 5184 GSTATASSTLGTAH-TPKVVTTMATMPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVST 5242

Query: 605  PATRMLKT 612
             ++ +L T
Sbjct: 5243 VSSSVLTT 5250


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score =  140 bits (354), Expect = 1e-32
 Identities = 342/1503 (22%), Positives = 524/1503 (34%), Gaps = 194/1503 (12%)

Query: 404  ATAATATSPTPNPVPSV-----------PANPPKSPAPAAAAPAVQPLTQVGITLLPQAA 452
            A++A+    TP PV S+           P   P S +   A P +  +T         A 
Sbjct: 1158 ASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLL--VTDTSSASTGHAT 1215

Query: 453  PAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTP---LVTMRPASQA 509
            P P T  +           +++P+AA T     +       A+TG     LVT   +   
Sbjct: 1216 PLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVST 1275

Query: 510  GKA---PVTVTSLPAGVRMVVPTQ--SAQGTVIGSSPQMSGMAALAAAAAATQKIP---P 561
            G     PVT TS  A    V P    S      G +  +   +  +A+   T  +P   P
Sbjct: 1276 GDTTPLPVTSTS-SASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSP 1334

Query: 562  SSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSV 621
            SSA T  + P   T     +V+ G TT          P+ V++ ++     A     TS+
Sbjct: 1335 SSASTGDTTPLPVT--DASSVSTGHTT----------PLHVTDASSASTGQATPLPVTSL 1382

Query: 622  SSATNTSTRPIITVHKSGTVTVAQQAQVVTTV----VGGVTKTITLVKSPISVPGGSALI 677
            SS +   T P+     S   T      +VT       G  T       S +S    ++L 
Sbjct: 1383 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLP 1442

Query: 678  SNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT 737
              +    S   T P+  +  T  ASTG  T ++ T            V++ D  P  + +
Sbjct: 1443 VTIPSAASTGHTTPLPVTD-TSSASTGQATSLLVTD--------TSSVSTGDTTPLPVTS 1493

Query: 738  TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSP-----GI 792
            T+ AS     P    +   SPS+   G  T +    +S+  T        +SP     G 
Sbjct: 1494 TSSASTGHVTP----LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGD 1549

Query: 793  KSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMG 852
             +P+ +     +++G   P  + T+    +TGH            + G       T P+ 
Sbjct: 1550 TTPLPVTDASSVSTGHTTPLPV-TSPSSASTGHTTPLPVTDTSSASKGD------TTPL- 1601

Query: 853  GVRLVTPVTV--SAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPI 910
                  PVT   SA     T L V  T+  +T  T    V+ + + + GH+T   + +P 
Sbjct: 1602 ------PVTSPSSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPS 1655

Query: 911  TTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVE 970
            +     AT        +A T  A    +T     TT   T  PV+       +++ S  +
Sbjct: 1656 SASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTD------VSSASTGQ 1709

Query: 971  AQPVHDLPVSILASPTTEQ--PTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNT 1028
            A P   LPV+ L+S +T    P    + + +  G   P  VT   S    +      T+T
Sbjct: 1710 ATP---LPVTSLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTGQATPLPVTDT 1766

Query: 1029 ATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTT 1088
            ++   V+     P P          +     VT       G  + +    P       TT
Sbjct: 1767 SS---VSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTT 1823

Query: 1089 NTATTATSNMAGQHGCSNP---PCETHETGTTNTATTAMSSVGANHQRD--ARRACAAGT 1143
                T  S+ +     S P   P       TT+   T  SSV   H        A +  T
Sbjct: 1824 PLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVST 1883

Query: 1144 PAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGG 1203
                 + V T    A+ G  +       S+ ST     AT  P +       S++    G
Sbjct: 1884 GDTTPLPV-TDTNSASTGDTTPLHVTDASSVSTGH---ATSLPVT-------SLSSASTG 1932

Query: 1204 RSPAFVQLAPLSSKVRLSSP-SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCE-SL 1261
             +      +P S+    ++P  + D  +    HA S      SSV  G     PV + S 
Sbjct: 1933 DTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASS 1992

Query: 1262 QGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQR----VC 1317
                 +T + VT   ++    AT   V S     T +T       TS+A + Q     V 
Sbjct: 1993 VSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVT 2052

Query: 1318 SNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGT-TMSVSVGAL 1376
            S     T +T  T    T+ S+  TG         A      H T+   T   SVS G  
Sbjct: 2053 SLSSVSTGDT--TPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTG-- 2108

Query: 1377 LPDATSSHRTVESGL---EVAAAPSVTPQ-AGTALLAPFP--------TQRVCSNPPCET 1424
               AT+ H T  S L   +    P  +P  A T    P P        T    S P  +T
Sbjct: 2109 --HATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDT 2166

Query: 1425 HETGTTHTAT---TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLT 1481
                T H  +   T TS+ S+    P   +D     + Q   + +TS S+ +T  +  L 
Sbjct: 2167 SSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLL 2226

Query: 1482 RAVTTVT---QSTPVP---------GPSVPPP--EELQVSPGPRQQLPPRQL-------- 1519
               T+     Q+TP+P         G + P P  +   VS G    LP   L        
Sbjct: 2227 VTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVSTGDT 2286

Query: 1520 ----LQSASTALMGESA-----EVLSASQ---TPELPAAVDLSSTGEPSS---GQESAGS 1564
                + S S+A  G +      +  SAS    TP    ++  +STG+ +       S+ S
Sbjct: 2287 TPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSAS 2346

Query: 1565 AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG-TTTLMVTGLTPEELAVTAAAEAA-A 1622
               AT +      + S  D   LP    + A +G TT L VT  +      T        
Sbjct: 2347 TGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDT 2406

Query: 1623 QAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT-VTQAELGHLSAEGQEGQATT 1681
             +A+T  A  L +  +  A+      TG   DT+    T V+ A  GH         AT 
Sbjct: 2407 SSASTGHATHLPVTGLSSAS------TG---DTTRLPVTNVSSASTGH---------ATP 2448

Query: 1682 IPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVP 1741
            +P+  T              +  +    H  P   L   D+ +    ++  L   + +  
Sbjct: 2449 LPVTSTSSASTGDTTPLPGTDTSSVSTGHTTP---LLVTDASSVSTGDTTRLPVTSPSSA 2505

Query: 1742 STVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPP 1801
            ST    P   T++ + S     P PV  AS    + A +L   +    S G    LP   
Sbjct: 2506 STGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTD 2565

Query: 1802 SKA 1804
            + A
Sbjct: 2566 TSA 2568



 Score =  137 bits (345), Expect = 1e-31
 Identities = 344/1546 (22%), Positives = 543/1546 (35%), Gaps = 173/1546 (11%)

Query: 375  ANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPA--A 432
            A+   L V+  + A+ D    +L   D+ + +     P P   PS  +    +P P   A
Sbjct: 1772 AHATPLPVTGLSSASTDD-TTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDA 1830

Query: 433  AAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP 492
            ++ +    T + +T+ P +A +  TT+    LP    SS+S   A       A    TG 
Sbjct: 1831 SSASTGDTTSLPVTI-PSSASSGHTTS----LPVTDASSVSTGHATSLLVTDASSVSTGD 1885

Query: 493  QATTGTPLVTMRPASQAGKAPVTVT---SLPAGVRMVVPTQSAQGTVIGSSPQMSGMAAL 549
              TT  P+     AS     P+ VT   S+  G    +P  S      G +  +   +  
Sbjct: 1886 --TTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPS 1943

Query: 550  AAAAAATQKIP---PSSAPT--VLSVPA-GTTIVKTMAVTPGTTTLPATVKVA-SSPVMV 602
            +A++  T  +P    SS PT    S+P    + V T   TP   T  ++V    ++P+ V
Sbjct: 1944 SASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPV 2003

Query: 603  SNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT 662
            ++ ++     A     TS+SSA+   T P+  V  + + +  Q   +  T +  V+   T
Sbjct: 2004 TDTSSVSTGQATPLPVTSLSSASTGDTTPL-PVTDTSSASTGQDTPLPVTSLSSVSTGDT 2062

Query: 663  L---VKSPISVPGGSA---LISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL 716
                V SP S   G A   L+++   V +   T  + T A     STG  T +  T    
Sbjct: 2063 TPLPVTSPSSASTGHATPLLVTDASSVSTGHATSLLVTDA--SSVSTGHATALHVTDA-- 2118

Query: 717  PAGTILKLVTSADGKPTTIITTTQASGAGTKPT-ILGISSVSP--STTKPGTTTIIKTIP 773
                    +++ D  P  + + + AS   T P  +   SSVS   +T+ P T T      
Sbjct: 2119 ------SSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHATSLPVTDT------ 2166

Query: 774  MSAIITQAGATGVT----SSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQG 829
             SA    A +  VT    +S G  +P+ +  T   ++G   P  + T+    +TGH    
Sbjct: 2167 SSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPV-TSPSSASTGHAIPL 2225

Query: 830  VTQVVLKGAPGQ----PGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGT 885
            +       + GQ    P T L +   G    +     S+V     T     +  VT+L +
Sbjct: 2226 LVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDASSVSTGHAT-----SLPVTSLSS 2280

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLT 945
            V+   +T L      S S   ATP+      +  +         ++S+A T  T    +T
Sbjct: 2281 VSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPVT 2340

Query: 946  TPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASP----TTEQPTATVTIADSGQ 1001
            +P+      + P  VT  ++ S  +  P   LPV+  +S     TT  P    + A +G 
Sbjct: 2341 SPSSASTGHATPLHVTDASSVSTGDTTP---LPVTSSSSASSGHTTPLPVTDASSASTGD 2397

Query: 1002 GDVQPGTVTLVCSNPPCETH---------ETG-TTNTATTTVVANLGGHPQPTQVQFVCD 1051
                P T T   S     TH          TG TT    T V +   GH  P     V  
Sbjct: 2398 TTPLPVTDTSSASTGHA-THLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLP---VTS 2453

Query: 1052 RQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG-----TTNTATTATSNMAGQHGCSN 1106
               A+    T   G    SV    + P   T  +      TT    T+ S+ +  H    
Sbjct: 2454 TSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPL 2513

Query: 1107 PPCETHETGTTNTA---TTAMSSVGANH--------QRDARRACAAGTPAVIRISVATG- 1154
            P  +T    T +T     T  SS+   H           A    A   P     + +TG 
Sbjct: 2514 PVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGH 2573

Query: 1155 ALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPL 1214
            A      S S   T  T+    T T  A+    +  P+   S A   G  +P  V     
Sbjct: 2574 ATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSA-STGDTTPLPVTDTSS 2632

Query: 1215 SSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCE-SLQGGSPSTTVTVT 1273
            +S    +   + +  +    HA      + SS   G     PV + S      +T++ VT
Sbjct: 2633 ASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVT 2692

Query: 1274 ALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTA 1333
               ++    AT   V       +  T T    T +++ S     S P  +     T H A
Sbjct: 2693 DASSVFTGHATSLPVTIPSSASSGHT-TPLPVTDASSVSTGHATSLPVTDASSVSTGH-A 2750

Query: 1334 TTATSNGGTGQPEGGQQPPAGRPCETHQTTSTG--------TTMSVSVGALLPDATSSHR 1385
            T       +    G   P    P  +  + STG         T S S G   P   +S  
Sbjct: 2751 TPLPVTDASSVSTGHATP---LPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLS 2807

Query: 1386 TVESGLEVAAAPSVTPQAGTALLAPFP--------TQRVCSNPPCETHETGTTHTA---T 1434
            +V +G       + T  A T      P        T      P  +T    T H      
Sbjct: 2808 SVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPV 2867

Query: 1435 TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSA----------ITTTVSSTLTRA- 1483
            T TS+ S         +D   + +     +++TS S+          +T T S++   A 
Sbjct: 2868 TDTSSASIGHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHAN 2927

Query: 1484 ---VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSA---STALMGESAEVLSA 1537
               VT+ + ++      +P  +    S G    LP   L   +   +T L   S    S 
Sbjct: 2928 PLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSAST 2987

Query: 1538 SQTPELPAAVDLSSTGEPSSGQESA----GSAVVATVVVQPPPPTQ----SEVDQLSLPQ 1589
              T  LP    ++ T   S+GQ +A     ++  +T    P P T     S      LP 
Sbjct: 2988 GHTTPLP----VTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPV 3043

Query: 1590 ELMAEAQAG-TTTLMVTGLTPEELA-VTAAAEAAAQAAATEEAQALAIQAV--------- 1638
              ++    G TT L VT  +       T      A +A+T +A  L + ++         
Sbjct: 3044 TSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTT 3103

Query: 1639 -LQAAQQAVMGTGEP-----MDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELA 1692
             L     +   TG        DTS A+   T +     ++    G  T++P+  T     
Sbjct: 3104 PLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSST 3163

Query: 1693 ALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTAT 1752
                   + E  +    H  P   L   D+ +     +  L+  + +  ST    P   T
Sbjct: 3164 GDTTPLLVTETSSVSTGHATP---LLVTDASSASTGHATPLHVTSPSSASTGDTTPVPVT 3220

Query: 1753 ESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLP 1798
            ++ + S     P PV   S A       L        S G    LP
Sbjct: 3221 DTSSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLP 3266



 Score =  137 bits (345), Expect = 1e-31
 Identities = 307/1269 (24%), Positives = 461/1269 (36%), Gaps = 156/1269 (12%)

Query: 383  SWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQ 442
            S  +V+T D+  L +     P++A+T  + TP PV         S A    A A+ P+T 
Sbjct: 2965 SLSSVSTGDTTPLPVTS---PSSASTGHT-TPLPVTDT------SSASTGQATAL-PVTS 3013

Query: 443  VGITLLPQAAPAPPTTT----TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQ-ATTG 497
                      P P T T    T Q  P +P +S+S  +   T  +P    VT P  A+TG
Sbjct: 3014 TSSASTGDTTPLPVTDTSSASTGQATP-LPVTSLSSVSTGDTTPLP----VTSPSSASTG 3068

Query: 498  --TPL-VTMRPASQAGKA-PVTVTSLPA---GVRMVVPTQSAQGTVIGSSPQMSGMAALA 550
              TPL VT   ++  G+A P+ VTSL +   G    +P  S      G +  +      +
Sbjct: 3069 HATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATSLPVTDTSS 3128

Query: 551  AAAAATQKIP---PSSAPT--VLSVPA-GTTIVKTMAVTPGTTTLPATVKVA-SSPVMVS 603
            A+   T  +P    SSA T    S+P   T+   T   TP   T  ++V    ++P++V+
Sbjct: 3129 ASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVTETSSVSTGHATPLLVT 3188

Query: 604  NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVT------------VAQQAQVVT 651
            + ++     A     TS SSA+   T P+     S   T             A       
Sbjct: 3189 DASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGHATPLPVTGLSSASTGDTTR 3248

Query: 652  TVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQ 711
              V  ++   T   +P+ V   S++  + G  M +  T P  +SA TG A+  PVT    
Sbjct: 3249 LPVTDISSASTGQATPLPVTNTSSV--STGDTMPLPVTSP--SSASTGHATPLPVTSTSS 3304

Query: 712  TKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIK- 770
                      +   +SA    TT +  T  S A T  T   +   SPS+   G TT +  
Sbjct: 3305 ASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTT-PLPVTSPSSASTGHTTPLHV 3363

Query: 771  TIPMSAIITQAGATGVT----SSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHG 826
            TIP SA         VT    +S G  +P+ +  T  +++G   P  + T++  ++TG  
Sbjct: 3364 TIPSSASTGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPV-TSLSSVSTGDT 3422

Query: 827  QQGVTQVVLKGAPGQ----PGTILRTVPMGGVRLVTPVTVSAVK-----PAVTTLVVKGT 877
                       + GQ    P T L +V  G    +     S+V      P   T     +
Sbjct: 3423 TPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSAS 3482

Query: 878  TGVTTLGTVTGTVSTSLAGA----------------------GGHSTSASLATPITTLGT 915
            TG TT   VT T S S   A                         S S   ATP+    T
Sbjct: 3483 TGDTTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDT 3542

Query: 916  IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTL------------- 962
             +  +           S+A T       +T P+ +    + P  VT              
Sbjct: 3543 SSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLH 3602

Query: 963  ITAPSGVEAQPVHDLPVSILASPTTEQPT-ATVTIADS-GQGDVQPGTVTLVCSNPPCET 1020
            +T+PS      V  LPV+  +S +T   T   VT A S   G   P  VT   S    +T
Sbjct: 3603 VTSPSSASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDT 3662

Query: 1021 HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC 1080
                 T+T++ +        P P          +     VT       G    +    P 
Sbjct: 3663 TPLPVTDTSSASTGQ---ATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPS 3719

Query: 1081 ETHETGTTNTATTATSNMAGQHGCSNP--PCETHETG-TTNTATTAMSSVGANHQR--DA 1135
                  T     T+ S+ +  H    P     +  TG TT    T  SS    H      
Sbjct: 3720 SVSTGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPV 3779

Query: 1136 RRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATS----TTMTVMATGAPCSAGP 1191
                +A T    R+ V T    A+ G  +      TS+ S    T + V  T +  +   
Sbjct: 3780 TDTSSASTDDTTRLPV-TDVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHA 3838

Query: 1192 LLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS-----HAVSTAAMTRSS 1246
               P  +R     S       P++    +S+     LP    S     HA      + SS
Sbjct: 3839 TSLPVTSR--SSASTGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSS 3896

Query: 1247 VGAGEPRMAPVCESLQGGSPSTT-VTVTALEALLCPSATVTQVCSNPPCETHETGTTNTA 1305
               G     PV  +    +  TT + VT   +L    AT   V S     +   G T+T 
Sbjct: 3897 ASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSP---SSASRGDTSTL 3953

Query: 1306 TTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTST 1365
              ++A SA    + P   T  +  +   TT      T     GQ  P   P  +  + ST
Sbjct: 3954 PVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPL--PVTSLSSVST 4011

Query: 1366 GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425
            G T  + V   +P + SS  T  + L V  A SV+   GT    P P   V S     T 
Sbjct: 4012 GDTTPLPV--TIPSSASSGHT--TSLPVTDASSVSTGHGT----PLP---VTSTSSASTG 4060

Query: 1426 ETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTL----T 1481
            +  TT    T TS+ S+    P   +D     +     + +TS S+++T  ++ L     
Sbjct: 4061 D--TTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSA 4118

Query: 1482 RAVTTVTQSTPV----PGPSVPPPEELQVSPGPRQQL-PPRQLLQSASTALMGESAEVLS 1536
             + +TV+  +P+    PG + P    L+   G R    PP    Q+  + +   +    S
Sbjct: 4119 TSASTVSSDSPLKMETPGMTTP---SLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRS 4175

Query: 1537 -ASQTPELP 1544
             A+  P LP
Sbjct: 4176 TAAPIPILP 4184



 Score =  136 bits (343), Expect = 2e-31
 Identities = 333/1538 (21%), Positives = 516/1538 (33%), Gaps = 204/1538 (13%)

Query: 389  TADSYLLQLQKYDIPATAATATSPTPNP---------VPSVPANPPKSPAPAAAAPAVQP 439
            T    LL    Y +     TATSP+ +P         + + P+    +    + +P   P
Sbjct: 573  TTGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESP 632

Query: 440  -LTQVGITLLPQAAPAPPTTTTIQVLP-----TVPGSSISV----PTAARTQGVPAVLKV 489
             ++Q G T  PQ      TT ++  +      T PGSS +     P+    Q  P +   
Sbjct: 633  AVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAA 692

Query: 490  -------TGPQATTGTPLVTMRPASQA-----GKAPVTVTSLPAGVRMVVPTQSAQGTVI 537
                   TG   TT  P   ++ A  +     G +  T  S    + +     S  G   
Sbjct: 693  TTFAPAPTGDGHTTQAPTTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPE 752

Query: 538  GSSPQMSGMAALAAAAAATQ----KIPPSSAPTVLSVPA--GTTIVKTMAVTPGTTTLPA 591
            G     S   +   AAA T     +   +S  T  S PA  G+        TP ++    
Sbjct: 753  GQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASG 812

Query: 592  TVKVASSPVMVSNPATRMLKTAAAQVGTS------VSSATNTSTRPIITVHKSGTVTVAQ 645
            T    S  +  S   TR     +    T+      +S++ +    P+ T   S  V    
Sbjct: 813  TTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTF 872

Query: 646  QAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGP 705
               +      G     +   SP + P  +A IS + +      ++   T ++  QA    
Sbjct: 873  HPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQA---- 928

Query: 706  VTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSP------S 759
             T    T  P P       +TS    P T   T   SG+G   T   IS+ +P      S
Sbjct: 929  -TDTFSTVPPTPPSITSTGLTS----PQTETHTLSPSGSGKTFTTALISNATPLPVTYAS 983

Query: 760  TTKPGTTTIIKTIPMSAIIT-QAGATGVTS----SPGIKSPITIITTKVMTSGTGAPAKI 814
            +   G TT +     S++ T  A    VTS    S G  +P+ +  T   ++G   P   
Sbjct: 984  SASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLP- 1042

Query: 815  ITAVPKIATGHGQQGVTQVVLKGAPGQ----PGTILRTVPMGGVR-LVTPVTVSAVKPAV 869
            +T+    +TG             + G     P T L +   G    L    T SA     
Sbjct: 1043 VTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHA 1102

Query: 870  TTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPT-A 928
            T+L V  T+ V+T  T    V+ + + + GH+TS     P+T   +++T  +  ++ T A
Sbjct: 1103 TSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATS----LPVTDTSSVSTGHTTPLHVTDA 1158

Query: 929  ITVSAAQTT---LTAAGGLTTPTITMQPVSQPTQVT-------LITAPSGVEAQPVHDLP 978
             + S  Q T   +T+   ++T   T  PV+ P+  +       L+T  S         LP
Sbjct: 1159 SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLP 1218

Query: 979  VSILASPTTEQPTA---------------TVTIADSGQGDVQPGTVTLVCSNPPCETHET 1023
            V+  +S +T+  T+                + + D+        T  LV       T + 
Sbjct: 1219 VTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGD- 1277

Query: 1024 GTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAAS--LVTSTVGQQNGSVVRVCSNPPCE 1081
             TT    T+  +   GH  P  V          A+   VTS      G  + +    P  
Sbjct: 1278 -TTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSS 1336

Query: 1082 THETGTTNTATTATSNMAGQH--------------GCSNP----PCETHETG-TTNTATT 1122
                 TT    T  S+++  H              G + P       +  TG TT    T
Sbjct: 1337 ASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVT 1396

Query: 1123 AMSSVGANH--------QRDARRACAAGTPAVIRISVATG-ALEAAQGSKSQCQTRQTSA 1173
            + SS    H           A    A   P     SV+T  A        S   T  T+ 
Sbjct: 1397 SPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTP 1456

Query: 1174 TSTTMTVMA-TGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR 1232
               T T  A TG   S   L+  + +   G  +P  V     +S   ++   +    +  
Sbjct: 1457 LPVTDTSSASTGQATSL--LVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAS 1514

Query: 1233 HSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTT-VTVTALEALLCPSATVTQVCSN 1291
              HA      + SS   G+    PV       +  TT + VT   ++     T   V S 
Sbjct: 1515 TGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSP 1574

Query: 1292 PPCETHETGTTNTATTSNA--GSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQ 1349
                T  T       TS+A  G    +    P       TT    T TS+  TG      
Sbjct: 1575 SSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTG------ 1628

Query: 1350 QPPAGRPCETHQTTSTGTT--MSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTAL 1407
                        TT    T   S+S G   P   +S  +  +G       + T  A T  
Sbjct: 1629 -----------DTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGH 1677

Query: 1408 LAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNIT 1467
              P P   + S          TT    T  S+ S+ Q  P   +    V +     + +T
Sbjct: 1678 ATPLPVTGLSS-----ATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVT 1732

Query: 1468 SSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTAL 1527
            S S+ +T  +S L   VT  + ++      +P  +   VS      LP    L SAST  
Sbjct: 1733 SPSSASTGHASPL--LVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTG-LSSAST-- 1787

Query: 1528 MGESAEVLSASQTPELPAA-VDLSSTGE----PSSGQESAGSAVVATVVVQPPPPTQSEV 1582
                        T  LP   V  +STG+    P +   SA +     + V     + S  
Sbjct: 1788 ----------DDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPV-TDASSASTG 1836

Query: 1583 DQLSLPQELMAEAQAG-TTTLMVTGLTPEELA-VTAAAEAAAQAAATEEAQALAIQAVLQ 1640
            D  SLP  + + A +G TT+L VT  +       T+     A + +T +   L +     
Sbjct: 1837 DTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPV----T 1892

Query: 1641 AAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQL 1700
                A  G   P+  ++A++  T             G AT++P+               +
Sbjct: 1893 DTNSASTGDTTPLHVTDASSVST-------------GHATSLPVTSLSSASTGDTTPLPV 1939

Query: 1701 QEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNT 1760
                +    H  P   L   D+ + P   +  L     +  ST    P   T++ + S  
Sbjct: 1940 TSPSSASSGHTTP---LPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTG 1996

Query: 1761 FVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLP 1798
               P PV   S      A  L   +    S G    LP
Sbjct: 1997 HATPLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLP 2034



 Score =  117 bits (293), Expect = 1e-25
 Identities = 316/1463 (21%), Positives = 499/1463 (34%), Gaps = 183/1463 (12%)

Query: 445  ITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMR 504
            + LLP   P     T I       GS  + P  + T    A L+     A++ T    + 
Sbjct: 19   LCLLPHVVPGTTEDTLIT------GSKTAAPVTS-TGSTTATLEGQSTAASSRTSNQDIS 71

Query: 505  PASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSA 564
             +SQ  +   T T+  A    +  TQ    T+  SSP +  +   A     T   P S  
Sbjct: 72   ASSQNHQTKSTETTSKAQTDTL--TQMMTSTLF-SSPSVHNVMETAPPDEMTTSFPSSVT 128

Query: 565  PTVLSVPAGTTIVKTMAVTPGT-TTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSS 623
             T++         KT+ +T  T +TL  T + +++    S P T  +   A Q G S ++
Sbjct: 129  NTLMMTS------KTITMTTSTDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTT 182

Query: 624  ATNTS------------TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVP 671
            +  TS            TR   T  +S T T+  +     +    V      V    S P
Sbjct: 183  SWRTSIQDTSASSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTS-P 241

Query: 672  GGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGK 731
             G    S+L    SV  T  + +  +T   STG           +P    L  VTSA   
Sbjct: 242  SGETATSSL---CSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSA--- 295

Query: 732  PTTIITTTQASGAGTKPTILGISSVSPST--TKPGTTTIIKTIPMSAIITQAGATGVTSS 789
               ++T       G  P     +S   +T  +K   T  ++T  +S I T    T VT+S
Sbjct: 296  --ALVTFDPE---GQSPATFSRTSTQDTTAFSKNHQTQSVETTRVSQINTLNTLTPVTTS 350

Query: 790  PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTV 849
              + SP     +  ++  T    +  T+ P   +      VT  V +    +  T+  T 
Sbjct: 351  TVLSSPSGFNPSGTVSQETFPSGETTTSSPSSVSNTFL--VTSKVFRMPTSRDSTLGNTE 408

Query: 850  PMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTT--------LGTVTGTVSTSLAGAGGH- 900
                  L    T+SA+   V+T+    T             + T   T  +  A   G  
Sbjct: 409  ETS---LSVSGTISAITSKVSTIWWSDTLSTALSPSSLPPKISTAFHTQQSEGAETTGRP 465

Query: 901  ----STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQ 956
                S S  ++  I TL    T  S   +    T S  +   T+ G  T   +T  P S 
Sbjct: 466  HERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAATR-LVTGNP-ST 523

Query: 957  PTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNP 1016
             T  T+   PS V A       +     PTT    +T     +G G     T        
Sbjct: 524  GTAGTIPRVPSKVSA-------IGEPGEPTTYSSHSTTLPKTTGAGAQTQWT-------- 568

Query: 1017 PCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCS 1076
                 ETGTT  A       L   P  +  Q +    + A S  +S +  ++ S  +  +
Sbjct: 569  ----QETGTTGEA-------LLSSPSYSVTQMI----KTATSPSSSPMLDRHTS--QQIT 611

Query: 1077 NPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTN-----TATTAMSSVGANH 1131
              P   H T  + + +   S    Q G +  P  T E+ TT      T T  +++ G++ 
Sbjct: 612  TAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSF 671

Query: 1132 QRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGP 1191
                             IS AT    A  G         T A +T +    +    + GP
Sbjct: 672  TASGHSPSEIVPQDAPTISAATTFAPAPTGDG-----HTTQAPTTALQAAPSSHDATLGP 726

Query: 1192 LLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLP----AGRHSH-AVSTAA--MTR 1244
              G S+++         V   P   + + +S S    P    A  H+H A ST A   T+
Sbjct: 727  SGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQ 786

Query: 1245 SSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNT 1304
            +S  A          +    S   + T  +    +  S   T+  SNP  ++H T +T  
Sbjct: 787  TSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTE 846

Query: 1305 ATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCET----- 1359
              +++A       S     +   GT H   +  S  G    +     P+  P ET     
Sbjct: 847  LLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISR 906

Query: 1360 -HQTTSTGTTMSVSVGALLPDATSSHRTV-ESGLEVAAAPSVTPQAGTALLAPFPTQRVC 1417
              QT  T T+      +L   AT +  TV  +   + +    +PQ  T  L+P  + +  
Sbjct: 907  MAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTF 966

Query: 1418 SNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVS 1477
            +        +  T    T  S+ S+    P   +D   V +     + +TS S+++T  +
Sbjct: 967  TTALI----SNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHT 1022

Query: 1478 STLTRAVTTVTQS---TPVP---------GPSVPPP--EELQVSPGPRQQLPPRQLLQSA 1523
            + L    T+   +   TP+P         G S P P  +    S G    LP   L  ++
Sbjct: 1023 TPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSAS 1082

Query: 1524 -------------------STALMGESAEVLSASQTPELPAA-VDLSSTGEPSSGQESAG 1563
                               +T+L       +S   T  LP      +STG  +S   +  
Sbjct: 1083 TGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDT 1142

Query: 1564 SAV---------------VATVVVQPPPPTQ----SEVDQLSLPQELMAEAQAGTTTLMV 1604
            S+V                +T    P P T     S  D   LP    + A  G  T ++
Sbjct: 1143 SSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLL 1202

Query: 1605 TGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPM-DTSEAAATVT 1663
               T       A       A++     A ++   + +A      T  P+ DTS A+    
Sbjct: 1203 VTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQA 1262

Query: 1664 QAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSL 1723
             + L   ++    G  T +P+  T       V    +    +    H  P     P  SL
Sbjct: 1263 TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATP----LPVTSL 1318

Query: 1724 NDPAI-ESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLT 1782
            +  +  ++  L   + +  ST    P   T++ + S     P  V  AS A    A  L 
Sbjct: 1319 SSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLP 1378

Query: 1783 EVANGIESLGVKPDLP-PPPSKA 1804
              +    S G    LP   PS A
Sbjct: 1379 VTSLSSVSTGDTTPLPVTSPSSA 1401


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score =  138 bits (347), Expect = 6e-32
 Identities = 264/1188 (22%), Positives = 432/1188 (36%), Gaps = 150/1188 (12%)

Query: 405   TAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLP--QAAPAPPTTTTIQ 462
             T +  TS       +VP     +  P    P V     V  T +P    +P  P TT   
Sbjct: 10850 TPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSM 10909

Query: 463   VLPTVPGSSISVPTAARTQGVPAVLK--VTGPQATTGT---------------PLVTMRP 505
                    +S ++PT   + GVP V+   VT  +A T T               P +    
Sbjct: 10910 ATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILTFSLGEPETTPSMATSH 10969

Query: 506   ASQAGKA--------PVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQ 557
              ++AG A        P  VTSL A  R V  T     T+    P+ +   A +  A A+ 
Sbjct: 10970 GTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATSHGAEASS 11029

Query: 558   KIP------PSSAPTVLSVPAG--TTIVKTMAVTPG---TTTLPATVKVASSPVMVSNPA 606
              +P      P    ++++  +G  +T + T+ ++PG   TT   AT   A +   V  P 
Sbjct: 11030 TVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPT 11089

Query: 607   TRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKS 666
                  +       + S A  ++T PI+T+  S   T    A    T  G    +  L  S
Sbjct: 11090 VSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPETTPSMA----TSHGVEASSAVLTVS 11145

Query: 667   PISVPG--------GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQI-IQTKGPLP 717
             P  VPG          A+ S     +++   +P  T+++   +    ++ I      P  
Sbjct: 11146 P-EVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTV 11204

Query: 718   AGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI 777
              G +  LVTS+  + +     T AS   ++P      ++      PGT      +P   +
Sbjct: 11205 QGLVTSLVTSSGSETSAFSNLTVAS---SQP-----ETIDSWVAHPGTEAS-SVVPTLTV 11255

Query: 778   ITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG 837
              T    T ++    +  P    +T   T+   + +++ T +P   T    +  + +    
Sbjct: 11256 STGEPFTNISL---VTHPAESSSTLPRTTSRFSHSELDT-MPSTVTSPEAESSSAISTTI 11311

Query: 838   APGQPGTILRTVPMGGVRLVTPVTVSAVKPAV--TTLVVKGTTGVTTLGTVTGTVSTSLA 895
             +PG PG +   V   G        +SA  P V  +    + T    T   VT T      
Sbjct: 11312 SPGIPGVLTSLVTSSGR------DISATFPTVPESPHESEATASWVTHPAVTSTTVPRTT 11365

Query: 896   GAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG---GLTTPTITMQ 952
                 HS   +  +  T+ G  AT     I  +        + +T++G    +T PT+T+ 
Sbjct: 11366 PNYSHSEPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLS 11425

Query: 953   PVSQPTQVTLITAPSGVEAQPVHDLPVS---------ILASPTTEQPTATVTIADSGQGD 1003
                  T  + IT      +  +  LPVS         ++ S  T+  T   T+ ++    
Sbjct: 11426 SGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLTET---P 11482

Query: 1004  VQPGTVTLVCSNP-------PCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAA 1056
              +P T  +   +P       P  T +   + + TT  VA     P+ +            
Sbjct: 11483 YEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISPDM 11542

Query: 1057  ASLVTSTV---GQQNGSVVRVCSNPPCETHETGT--TNTATTATSNMAGQHGCSNPPCET 1111
             + LVTS V   G    +     S  P E   T T  T+ A T+T+        S+   +T
Sbjct: 11543 SDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDT 11602

Query: 1112  HETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQG------SKSQ 1165
               +  T+      S V                P V+   V + A + +        S  +
Sbjct: 11603 APSMVTSPGVDTRSGVPTT-------TIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGE 11655

Query: 1166  CQTRQTSAT----STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLS 1221
              +T  +SAT     T  TV     P S    +   +   P   +P    ++  +S    S
Sbjct: 11656 PETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTP----VSRTTSSFSHS 11711

Query: 1222  SPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTV-TVTALEALLC 1280
             SP    + A       S+A +T  S GA E   + +  S  G + STTV T+T    +  
Sbjct: 11712 SPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSS--GAATSTTVPTLTHSPGM-- 11767

Query: 1281  PSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNG 1340
                T   + ++P  ET +T   +T     + +   +   P  ET     T T ++  +  
Sbjct: 11768 -PETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLL 11826

Query: 1341  GTGQPEGGQQPPAG-------RPCETHQTTSTGT---TMSVSVGAL----LPDATSSHRT 1386
              TG       P A         P  TH  T T T   T ++S+G L    L   +SS  T
Sbjct: 11827 VTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLATSSSAET 11886

Query: 1387  VESGLEVAAAPSVTPQAGTALLAPFPTQRVCS----NPPCETH----ETGTTHTATTVTS 1438
               S L +  +P+V+  +  ++    P Q V S      P  T     E   T T TT+T 
Sbjct: 11887 STSTLTLTVSPAVSGLSSASITTDKP-QTVTSWNTETSPSVTSVGPPEFSRTVTGTTMTL 11945

Query: 1439  NMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTT 1486
               S    PP  +  +G   +T   +  + +++  TT  S T+ +  TT
Sbjct: 11946 IPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTT 11993



 Score =  123 bits (308), Expect = 2e-27
 Identities = 288/1343 (21%), Positives = 503/1343 (37%), Gaps = 167/1343 (12%)

Query: 401   DIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTT 460
             ++   ++TATS   +   ++P N   S   A   P V        T  P    +P  T T
Sbjct: 10621 ELDTVSSTATSHGADVSSAIPTNISPSELDALT-PLVTISGTDTSTTFPTLTKSPHETET 10679

Query: 461   IQVLPTVPGSSIS-----VPTAAR--TQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAP 513
                  T P  + S     +P  +   +   P++    G + ++  P++T+ P ++     
Sbjct: 10680 RTTWLTHPAETSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAE-DLVT 10738

Query: 514   VTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAG 573
               VTS      M +PT     T+    P+      +A+     +    S+ PT    PA 
Sbjct: 10739 SQVTSSGTDRNMTIPTL----TLSPGEPK-----TIASLVTHPEAQTSSAIPTSTISPAV 10789

Query: 574   TTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRM-LKTAAAQVG------TSVSSATN 626
             + +V +M  +    T      + +SP     PAT + L T  AQ        TS+   + 
Sbjct: 10790 SRLVTSMVTSLAAKTSTTNRALTNSP---GEPATTVSLVTHPAQTSPTVPWTTSIFFHSK 10846

Query: 627   TSTRPIITV-HKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISV--------PGGSALI 677
             + T P +T  H + + +      V T V G VT  +T  ++ IS         PG     
Sbjct: 10847 SDTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETT 10906

Query: 678   SNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT 737
              ++        +  + T  V+     G VT ++ T       T + ++T + G+P T  T
Sbjct: 10907 PSMATSHGEEASSAIPTPTVS-PGVPGVVTSLV-TSSRAVTSTTIPILTFSLGEPET--T 10962

Query: 738   TTQASGAGTK-----PTIL----GISSVSPSTTKPGTTTIIKTIPMS--------AIITQ 780
              + A+  GT+     PT+L    G+ +   ++++  T+T + T+ +S        ++ T 
Sbjct: 10963 PSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPSMATS 11022

Query: 781   AGATGVTSSPGIKSPITIITTKVMTSGTGA-----PAKIIT-----AVPKIATGHGQQGV 830
              GA   ++ P +   +  + T ++TS +G      P  I++       P +AT HG +  
Sbjct: 11023 HGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEAS 11082

Query: 831   TQVVLKG-APGQPGTILRTVPMGGVRLVTPV---TVSAVKPAVTTLVVKGTTGVTTLGTV 886
             + V     +PG  G +   V        T +   T+S+ +P  TT  +  + GV     V
Sbjct: 11083 SAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILTLSSSEPE-TTPSMATSHGVEASSAV 11141

Query: 887   TGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT 946
               TVS  + G      ++S A   TT+ T+ T+SS     T   V+ ++  + +A     
Sbjct: 11142 L-TVSPEVPGMVTSLVTSSRAVTSTTIPTL-TISSDEPETTTSLVTHSEAKMISA----I 11195

Query: 947   PTITMQPVSQPTQVTLITAPSGVEAQPVHDLPV---------SILASPTTEQPTATVTIA 997
             PT+ + P  Q    +L+T+ SG E     +L V         S +A P TE  +   T+ 
Sbjct: 11196 PTLAVSPTVQGLVTSLVTS-SGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLT 11254

Query: 998   DSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
              S     +P T   + ++P     E+ +T   TT+  ++      P+ V        +A 
Sbjct: 11255 VSTG---EPFTNISLVTHPA----ESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAI 11307

Query: 1058  S---------LVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPP 1108
             S         ++TS V      +       P   HE+  T +  T  +  +     + P 
Sbjct: 11308 STTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTSTTVPRTTPN 11367

Query: 1109  CETHETGTTNTATTAMSSVGANHQRDARRACAA-GTPAVIRISVATGALEAAQGSKSQCQ 1167
                 E  TT +  T   S GA    D      +   P ++   V +   + +    +   
Sbjct: 11368 YSHSEPDTTPSIAT---SPGAEATSDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTL 11424

Query: 1168  TRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKD 1227
             +     T+T+    +     SA P L  S    PG        +    +    + P++ +
Sbjct: 11425 SSGEPETTTSFITYSETHTSSAIPTLPVS----PGASKMLTSLVISSGTDSTTTFPTLTE 11480

Query: 1228  LPAGRHSHAVSTA--AMTRSSVGAGEPRMA--------PVCESLQGGSPSTTVTVTALE- 1276
              P    + A+     A T + V    P+ +        PV  +  G   S+ V+ T +  
Sbjct: 11481 TPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISP 11540

Query: 1277  -------ALLCPSATVTQVCSNPPCET-HETGTTNTATTSNAGSAQRVCSNPPCETHETG 1328
                    +L+  S T T        ET +E  TT T  T  A ++  V    P  +H   
Sbjct: 11541 DMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRG- 11599

Query: 1329  TTHTATTATSNGGTGQPEGGQQ---PPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHR 1385
              + TA +  ++ G     G      PP+     T Q TS+ T  S ++  L P       
Sbjct: 11600 -SDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPET 11658

Query: 1386  TVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMS-SNQ 1444
             T  S     A    T    T  +   P+    +     TH   T+   +  TS+ S S+ 
Sbjct: 11659 TASS-----ATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSP 11713

Query: 1445  DPPP--AASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPE 1502
             D  P  A S + E  S    +++  +   +T+ ++S+     TTV   T  PG    P  
Sbjct: 11714 DATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHSPG---MPET 11770

Query: 1503  ELQVSPGPRQQLPPR--------QLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGE 1554
                +S  PR +            Q+ ++ ++  +   AE  +A  T    +   L  TG 
Sbjct: 11771 TALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFTLLVTGT 11830

Query: 1555  PSSGQESAGSAVVA--TVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPE-- 1610
                      S  V+  T  +   P T++      +P   ++     TT L+ T  + E  
Sbjct: 11831 SRVDLSPTASPGVSAKTAPLSTHPGTETST---MIPTSTLSLGLLETTGLLATSSSAETS 11887

Query: 1611  ----ELAVTAAAEAAAQAAATEE 1629
                  L V+ A    + A+ T +
Sbjct: 11888 TSTLTLTVSPAVSGLSSASITTD 11910



 Score =  120 bits (302), Expect = 1e-26
 Identities = 276/1233 (22%), Positives = 461/1233 (37%), Gaps = 248/1233 (20%)

Query: 456  PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVT 515
            PT TT +V      S   V ++ RT        + GP  +T  P ++ R  ++   +P  
Sbjct: 6976 PTGTTAEV------SRTEVTSSGRTS-------IPGPSQSTVLPEISTRTMTRLFASPTM 7022

Query: 516  VTSLPAGVRMVVPTQSAQGTVIGSSPQ-------MSGMAALAAAAAATQKIP-------- 560
              S      M +PTQ+      GS+ Q        +  +     +  TQ+ P        
Sbjct: 7023 TES----AEMTIPTQTGPS---GSTSQDTLTLDTSTTKSQAKTHSTLTQRFPHSEMTTLM 7075

Query: 561  -----------------PSSAPTVLSVPAGTT---IVKTMAVTPGTTTLPATVKVASSPV 600
                             PSS P++LS+PA T+   I  T+ VT  ++ LP T  + SSPV
Sbjct: 7076 SRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPV 7135

Query: 601  MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIIT---------VHKSGTVTVAQQAQVVT 651
                  T ML T+   V +S    ++TS   + T         VH S T T A   ++ +
Sbjct: 7136 TT----TDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPS-TNTAASNVEIPS 7190

Query: 652  TVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKP--VQTSAVTGQASTGPVTQI 709
            +  G  + +  L  S  S       I++  +  +V  + P  ++TS +  ++ +    ++
Sbjct: 7191 S--GHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSLSPKL 7248

Query: 710  IQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAG-TKPTILGISSVSPSTTKPGTTTI 768
             +T   +   + ++  TSA     +I  TT+ S    T  +   IS  + ST  P  +T 
Sbjct: 7249 RETGSSVETSSAIE--TSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEISTT 7306

Query: 769  IKTI--PMSAIITQAGATGV---TSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIAT 823
             K I  P S I+ ++    +   TS PG  S  T       T  T     ++     +  
Sbjct: 7307 RKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTF------TLDTSTTPSLVITHSTMTQ 7360

Query: 824  GHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTL 883
                  +T +V +GA             G V   + + V    P  + L +         
Sbjct: 7361 RLPHSEITTLVSRGA-------------GDVPRPSSLPVEETSPPSSQLSLSAM------ 7401

Query: 884  GTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATL-----SSQVINPTAITVSAAQTTL 938
              ++ +  +S   A  HS+SAS+ T + T G + T      S++    +  ++S+    +
Sbjct: 7402 --ISPSPVSSTLPASSHSSSASV-TSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEI 7458

Query: 939  TAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIAD 998
             A   +TT T  + P S      + T+ SG      H+ P S+L    T + T+ +    
Sbjct: 7459 LATSEVTTDTEKIHPFSNTAVTKVGTSSSG------HESPSSVLPDSETTKATSAM---- 7508

Query: 999  SGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDR-QEAAA 1057
                    GT++++           G T+ +T T   +     Q      +  R +E + 
Sbjct: 7509 --------GTISIM-----------GDTSVSTLTPALSNTRKIQSEPASSLTTRLRETST 7549

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
            S  TS   + N  + +V +    E   T   + + T+ S                  G  
Sbjct: 7550 SEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMS------------------GPE 7591

Query: 1118 NTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTT 1177
             +  +   S+G   +  A         A + I+  TG  E+   S     T  T +   T
Sbjct: 7592 QSTMSQDISIGTIPRISASSVLTES--AKMTITTQTGPSESTLESTLNLNTATTPSWVET 7649

Query: 1178 MTVMATGAPCSAGPLLGPSMAREPGG---RSPAFV-QLAPLSSKVRLSSPSIKDLPAGRH 1233
             +++  G P    P +  SM R PGG    SP FV + +P SS +         LPA   
Sbjct: 7650 HSIVIQGFP---HPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPL--------SLPAVTS 7698

Query: 1234 SHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTT----------------VTVTALEA 1277
             H VST  +         P   PV   L  G  +TT                ++ T+ E 
Sbjct: 7699 PHPVSTTFLAHIP-----PSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHER 7753

Query: 1278 LLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVC---SNPPCETHETGTTHTAT 1334
            L     T      +P   +  TG TN ATTS+   +Q      S+P C T   G T   T
Sbjct: 7754 LTTYKDTAHTEAVHP---STNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLT 7810

Query: 1335 TATSNGGTGQPE---GGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGL 1391
            +  +   T + +        P  R     + TS+GT MS               TV S +
Sbjct: 7811 STPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMS---------------TVLSKV 7855

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETG--TTHTATTVTSNMSSNQDPPPA 1449
               A   ++ +  T++  P P Q   S P   T      +T    T ++ ++ N    P 
Sbjct: 7856 PTGATTEISKEDVTSI--PGPAQSTIS-PDISTRTVSWFSTSPVMTESAEITMNTHTSPL 7912

Query: 1450 ASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPG 1509
             +      +TQG S   TSS+   T   ST+++  +    ST +      P +   +SP 
Sbjct: 7913 GA------TTQGTSTLDTSSTTSLTMTHSTISQGFSHSQMSTLM---RRGPEDVSWMSPP 7963

Query: 1510 PRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVAT 1569
              ++  P       S +LM   A    +  +  LP ++  SS+  P +   ++G A    
Sbjct: 7964 LLEKTRP-------SFSLMSSPATTSPSPVSSTLPESI--SSSPLPVTSLLTSGLAKTTD 8014

Query: 1570 VVVQPPPP-TQSEVDQLSLPQELMAEAQAGTTT 1601
            ++ +   P T S  +  S   E++A ++  T T
Sbjct: 8015 MLHKSSEPVTNSPANLSSTSVEILATSEVTTDT 8047



 Score =  119 bits (298), Expect = 3e-26
 Identities = 344/1629 (21%), Positives = 570/1629 (34%), Gaps = 284/1629 (17%)

Query: 376   NTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAP 435
             +T+S+  +    +   ++LLQ  K D  ++A T++   P P       P     P  A+P
Sbjct: 10177 DTSSVTPTNTPSSPGSTHLLQSSKTDFTSSAKTSSPDWP-PASQYTEIPVDIITPFNASP 10235

Query: 436   AVQPLTQVGITLLPQAA-----------------PAPPTTTTIQVLPTVPGSSIS----- 473
             ++   T  GIT  P++                  P+  T +T  V+P++  +  S     
Sbjct: 10236 SITEST--GITSFPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTG 10293

Query: 474   VPTAARTQGVPAVLKVTGP-QATTGT-----PLVTMRPASQAGKAPVTVTSLPA--GVRM 525
             VP A    G P     +GP  AT  T     P  T  P S +       +++PA   +  
Sbjct: 10294 VPRAISGSGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITS 10353

Query: 526   VVPTQSAQGTVIG--SSPQMSGMAALAAAAAATQKIPPSSAP-------------TVLS- 569
                T     T +G  SS     +  ++    ++Q    SS+P             TV S 
Sbjct: 10354 SSATPYRVDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSA 10413

Query: 570   --VPA-GTTIVKTMAVTPGTTTLP------ATVKVASSPVMVSNPAT-RMLKTAAAQVGT 619
               VP+  T + +T  +    T +P       T++    P   ++PA+ + L T   +   
Sbjct: 10414 YQVPSLSTRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRME 10473

Query: 620   SVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV--------VGGVTKTITLVKSPISVP 671
             + ++A  T+T  + T  ++ T+T +     + T+        +     T  ++ +P   P
Sbjct: 10474 TTTTALKTTTTALKTTSRA-TLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFP 10532

Query: 672   G----GSALISNLGK---------VMSVVQTKPVQTSAVTGQ--ASTGPVTQIIQTKGPL 716
                   S+L ++LG            SV   +   T+++  +  A   PV Q +      
Sbjct: 10533 DVPETTSSLATSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSE 10592

Query: 717   PAGTILKLVTSADGKPT--------------TIITTTQASGAGTKPTI------------ 750
             P  T   ++  A+  PT              T+ +T  + GA     I            
Sbjct: 10593 PDTTASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISPSELDAL 10652

Query: 751   ---LGISSVSPSTTKPGTT---------------------TIIKTIPMSAIITQAGATGV 786
                + IS    STT P  T                     TI +TIP  +         +
Sbjct: 10653 TPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSI 10712

Query: 787   TSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTIL 846
              +SPG ++   I    +MT   GA   + + V    T    + +T   L  +PG+P TI 
Sbjct: 10713 ATSPGAETSSAI---PIMTVSPGAEDLVTSQVTSSGT---DRNMTIPTLTLSPGEPKTIA 10766

Query: 847   RTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH-STSAS 905
               V     +  + +  S + PAV+ LV   T+ VT+L   T T + +L  + G  +T+ S
Sbjct: 10767 SLVTHPEAQTSSAIPTSTISPAVSRLV---TSMVTSLAAKTSTTNRALTNSPGEPATTVS 10823

Query: 906   LAT-PITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLIT 964
             L T P  T  T+   +S   +  + T  +  T+  A      PT T+      T+V  + 
Sbjct: 10824 LVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPTVS-----TEVPGVV 10878

Query: 965   APSGVEAQPVHDLPVSILA-SPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHET 1023
              P    ++ V    + IL  SP   + T ++  +   +      T T+    P   T   
Sbjct: 10879 TPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLV 10938

Query: 1024  GTTNTATTTVVANLG---GHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPC 1080
              ++   T+T +  L    G P+ T         E A S V + + +  G V  + ++   
Sbjct: 10939 TSSRAVTSTTIPILTFSLGEPETTPSMATSHGTE-AGSAVPTVLPEVPGMVTSLVASSRA 10997

Query: 1081  ETHETGTTNTAT----TATSNMAGQHGC----SNPPCETHETGTTNTATTAMSSVGANH- 1131
              T  T  T T +      T +MA  HG     + P       G   +  T+ S V +   
Sbjct: 10998 VTSTTLPTLTLSPGEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSI 11057

Query: 1132  --------QRDARRACAAGTPAVIRISVATGALE-AAQGSKSQCQTRQTSATSTTMTVMA 1182
                     + +   + A    A    +V T  +     G  +   T   + TSTT+ ++ 
Sbjct: 11058 PTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIPILT 11117

Query: 1183  TGAPCSAGPLLGPSMAREPG-GRSPAFVQLAP---------LSSKVRLSSPSIKDLPAGR 1232
                  S+ P   PSMA   G   S A + ++P         ++S   ++S +I  L    
Sbjct: 11118 LS---SSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISS 11174

Query: 1233  HSHAVSTAAMTRSSVG--------AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSAT 1284
                  +T+ +T S           A  P +  +  SL   S S T   + L        T
Sbjct: 11175 DEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSETSAFSNLTVASSQPET 11234

Query: 1285  VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQ 1344
             +    ++P  E      T T +T          +N    TH   ++ T    TS      
Sbjct: 11235 IDSWVAHPGTEASSVVPTLTVSTGEP------FTNISLVTHPAESSSTLPRTTSR--FSH 11286

Query: 1345  PEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAG 1404
              E    P      E   +++  TT+S  +  +L    +S     SG +++A     P+  
Sbjct: 11287 SELDTMPSTVTSPEAESSSAISTTISPGIPGVLTSLVTS-----SGRDISATFPTVPE-- 11339

Query: 1405  TALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMS-SNQDPPPAASDQGEVESTQGDS 1463
                 +P  ++   S     TH   T+ T    T N S S  D  P+ +     E+T  D 
Sbjct: 11340 ----SPHESEATAS---WVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEAT-SDF 11391

Query: 1464  VNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPE------------------ELQ 1505
               IT S  +   V+S +T + T  + + P    S   PE                   L 
Sbjct: 11392 PTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIPTLP 11451

Query: 1506  VSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL-------PAAVDLSSTGEPSSG 1558
             VSPG  + L    L+ S+ T        +      PE        PA  +          
Sbjct: 11452 VSPGASKML--TSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKF 11509

Query: 1559  QESAGSAVVATVVVQPPPPTQSEV-------DQLSLPQELMAEAQAGTTTLMVT-GLTPE 1610
               S     +   +  P P   S V       D   L   L+  +   T+T   T   TP 
Sbjct: 11510 SHSKSDTTLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPY 11569

Query: 1611  ELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHL 1670
             E   TA         +T  +  +   +   +     M T   +DT     T T       
Sbjct: 11570 EPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTT------- 11622

Query: 1671  SAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIES 1730
                       +IP V+T Q     V       + A       P E    A S   P  ++
Sbjct: 11623 -------IPPSIPGVVTSQ-----VTSSATDTSTAIPTLTPSPGEPETTASSATHPGTQT 11670

Query: 1731  NCLNELAGTVPST--------VALLPSTATESLAPSNTFVAPQ----PVVVASPAKLQAA 1778
                  +  TVPS+        V   P T+T     +++F        PV+  SP    ++
Sbjct: 11671 GFTVPIR-TVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASS 11729

Query: 1779  ATLTEVANG 1787
             A LT ++ G
Sbjct: 11730 AVLTTISPG 11738



 Score =  115 bits (287), Expect = 6e-25
 Identities = 336/1664 (20%), Positives = 582/1664 (34%), Gaps = 251/1664 (15%)

Query: 373  VRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAA 432
            V+AN +  E    A+A +++     Q         T T   P P  S+P +         
Sbjct: 5128 VKANNSGHESHSPALADSETPKATTQM------VITTTVGDPAPSTSMPVHGSSETTNIK 5181

Query: 433  AAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP 492
              P      ++  T   Q +  P  T T  +L  VP  +I   T   + GV +  K++ P
Sbjct: 5182 REPTYFLTPRLRETSTSQESSFP--TDTSFLLSKVPTGTI---TEVSSTGVNSSSKISTP 5236

Query: 493  QATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVI--GSSPQMSGMAALA 550
                 T    + P +  G+ P   TS        + T+SA+ T+    S P+ +  + L 
Sbjct: 5237 DHDKST----VPPDTFTGEIPRVFTSS-------IKTKSAEMTITTQASPPESASHSTLP 5285

Query: 551  AAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTT---TLPATVKVASSPVMVSNPAT 607
               + T     + +      P  + +   M + PG     T P   + +S   ++S+PA 
Sbjct: 5286 LDTSTTLSQGGTHSTVTQGFPY-SEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAM 5344

Query: 608  RMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSP 667
                T+ + V ++   +  +S  P+  +  S  VT        TT V G T       SP
Sbjct: 5345 ----TSPSPVSSTSPQSIPSSPLPVTALPTSVLVT--------TTDVLGTT-------SP 5385

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTS 727
             SV      +S++             T A    ++   VT +  T G         L  S
Sbjct: 5386 ESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNV-GTSGSGHKSQSSVLADS 5444

Query: 728  ADGKPTTIITTTQASG----------------------AGTKPTILGISSVSPSTTKPGT 765
               K T +++TT   G                      A   P +   S+   +++   T
Sbjct: 5445 ETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRESSTSEKTSSTTET 5504

Query: 766  TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGH 825
             T    +P  AI TQA  T ++SS    S +   T     S TG   ++ T+ P +    
Sbjct: 5505 NTAFSYVPTGAI-TQASRTEISSSRTSISDLDRPTIAPDIS-TGMITRLFTS-PIMTKSA 5561

Query: 826  GQQGVTQVVLKGAPGQ---PGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTT 882
                 TQ    GA  Q   P     T+  GG    T  TVS   P      ++  T    
Sbjct: 5562 EMTVTTQTTTPGATSQGILPWDTSTTLFQGG----THSTVSQGFPHSEITTLRSRTPGDV 5617

Query: 883  LGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG 942
                T  V  + +G    S S +  +P+++     ++ S  +  TA+  S   TT    G
Sbjct: 5618 SWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSP-ESIPSSPLPVTALLTSVLVTTTNVLG 5676

Query: 943  GLTTPTITMQP--VSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
              +   +T  P  +S PTQ  L T       + +H       AS  T    A V  + SG
Sbjct: 5677 TTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMH-------ASMHTNTAVANVGTSISG 5729

Query: 1001 ---QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
               Q  V   + T   ++P   T   G T+ +T+T           +    +   ++   
Sbjct: 5730 HESQSSVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFETRIQTESTSSLIPGLRDTRT 5789

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTT 1117
            S   +TV + +  +  V   P   T E   T   T++ + ++G       P  + ET T 
Sbjct: 5790 SEEINTVTETSTVLSEV---PTTTTTEVSRTEVITSSRTTISGPDHSKMSPYISTETITR 5846

Query: 1118 NTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTR-QTSATST 1176
               +T     G+       +    GT +   +++ T +  + +G+ S    R   S  +T
Sbjct: 5847 --LSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETT 5904

Query: 1177 TMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPS-----IKDLPAG 1231
            TM+    G    + P +  + +       PA    + L S V  SSP+        L +G
Sbjct: 5905 TMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSGSSPTSALPVTSLLTSG 5964

Query: 1232 R---------HSHAVSTAAMTRSSVGAGEPRMAPVCESLQG-----GSPSTTVTVTALEA 1277
            R         HS  V+++  + SS  +GE   +    + +       +  T +  T    
Sbjct: 5965 RRKTIDMLDTHSELVTSSLPSASSF-SGEILTSEASTNTETIHFSENTAETNMGTTNSMH 6023

Query: 1278 LLCPSATVTQVCSN--PPCETHETGTTNTATTSNAGSAQ-----RVCSNPPC-------- 1322
             L  S ++    S   PP  T         +TS  GS +     R  ++P          
Sbjct: 6024 KLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDST 6083

Query: 1323 -----ETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALL 1377
                  T E+ T  ++ +  +     + E     P   P     T S   +         
Sbjct: 6084 ALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASAQSTKSPDIS--------- 6134

Query: 1378 PDATSSHR-----TVESGLEVAA--APSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT 1430
            P+A+SSH      T+ +   +A    PS     G   L           P   T +   +
Sbjct: 6135 PEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPSARTQDFVDS 6194

Query: 1431 HTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQS 1490
             T + + ++++      P ++++    S+Q   +  TS S +T+T+    T ++ +VT  
Sbjct: 6195 ETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTS- 6253

Query: 1491 TPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAV--- 1547
              VP P++    ++  +  P  + P     Q+    L    A   + +  P +  AV   
Sbjct: 6254 --VPTPTLAKITDMDTNLEPVTRSP-----QNLRNTLATSEATTDTHTMHPSINTAVANV 6306

Query: 1548 -------DLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQE-LMAEAQAGT 1599
                   +   T  P S    A SAVV T        +   +   S+P+   M + ++ T
Sbjct: 6307 GTTSSPNEFYFTVSPDSDPYKATSAVVITST------SGDSIVSTSMPRSSAMKKIESET 6360

Query: 1600 TTLMVTGL----TPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPM-- 1653
            T  ++  L    T +++  ++        A T     ++   +  +++ ++ GT +P   
Sbjct: 6361 TFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMS 6420

Query: 1654 -DTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHL 1712
             DTS  + T+     G   +E +     T P   T Q    L     +  +QA    H  
Sbjct: 6421 PDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQ--GTLTWDTSITTSQAGT--HSA 6476

Query: 1713 PTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASP 1772
             T   +  D      + S     ++GT P +V    S+++    P+ T  +P PV    P
Sbjct: 6477 MTHGFSQLDL---STLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAIT--SPSPVPTTLP 6531

Query: 1773 AKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQWFDVGVIKGTNVMVTHYFLPP 1832
                                 +P  P   +  P          G++K T+++ +   LPP
Sbjct: 6532 ES-------------------RPSSPVHLTSLPTS--------GLVKTTDMLASVASLPP 6564

Query: 1833 DDAVPSDDDLGTVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPG 1892
            +    S     T  D    +K  + P T       G     +  +S + A+         
Sbjct: 6565 NLGSTSHKIPTTSEDIKDTEK--MYPSTNIAVTNVGTTTSEKESYSSVPAYS-------- 6614

Query: 1893 APCAIKISKSPDGAHLTWEPPSVTSGKIIEYSVYLAIQSSQAGG 1936
                              EPP VTS  +  +++   I S+   G
Sbjct: 6615 ------------------EPPKVTSPMVTSFNIRDTIVSTSMPG 6640



 Score =  108 bits (269), Expect = 7e-23
 Identities = 307/1464 (20%), Positives = 535/1464 (36%), Gaps = 260/1464 (17%)

Query: 427  SPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT---VPGSSISVPTAARTQGV 483
            SP  A  A ++     + +T  P      P T+T+Q   T   V  +S+  PT A+   +
Sbjct: 6211 SPFSAEEANSLSSQAPLLVTTSPS-----PVTSTLQEHSTSSLVSVTSVPTPTLAKITDM 6265

Query: 484  ----------PAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLP------------- 520
                      P  L+ T   +   T   TM P+     A V  TS P             
Sbjct: 6266 DTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSINTAVANVGTTSSPNEFYFTVSPDSDP 6325

Query: 521  --AGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAA-----------AATQKIPPSSAPTV 567
              A   +V+ + S    V  S P+ S M  + +             + +QKI  SS  + 
Sbjct: 6326 YKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQKIGSSSDTST 6385

Query: 568  LSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRML--------------KTA 613
            +   A T     ++ T  T++   +++    P M  + +TR +              +T 
Sbjct: 6386 VFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTFAGLTKSEERTI 6445

Query: 614  AAQVGTSVSSATNTST-RPIITVHKSGT---VTVAQQAQVVTTVVGGVTKTITLVKSPIS 669
            A Q G   +++  T T    IT  ++GT   +T       ++T+   V + I+   SP S
Sbjct: 6446 ATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSRVPEYIS-GTSPPS 6504

Query: 670  VPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSAD 729
            V   S+  S+L  + ++    PV T+    + S+      + T G +    +L  V S  
Sbjct: 6505 VEKTSS-SSSLLSLPAITSPSPVPTTLPESRPSSPVHLTSLPTSGLVKTTDMLASVASLP 6563

Query: 730  GKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIK---------------TIPM 774
                +       +    K T     S + + T  GTTT  K               T PM
Sbjct: 6564 PNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTSEKESYSSVPAYSEPPKVTSPM 6623

Query: 775  SAIITQAGATGVTSSPGIKSPITIITTKVMTS------GTGAPAKIITA------VPKIA 822
                        TS PG  S IT I  +   S      GT      I +      + K+ 
Sbjct: 6624 VTSFNIRDTIVSTSMPG-SSEITRIEMESTFSLAHGLKGTSTSQDPIVSTEKSAVLHKLT 6682

Query: 823  TGHGQQGVTQVVLKGAPGQPGTILRT-VPMGGVRLV--TPVTVSAVKPAVTTLVVK--GT 877
            TG  +   T+V        PG    T  P     ++   P+++   + +  T++ +    
Sbjct: 6683 TGATETSRTEVASSRRTSIPGPDHSTESPDISTEVIPSLPISLGITESSNMTIITRTGPP 6742

Query: 878  TGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTT 937
             G T+ GT T    T+ + AG HS  A+   P + + T+     ++++ T I  S  +T+
Sbjct: 6743 LGSTSQGTFTLDTPTTSSRAGTHS-MATQEFPHSEMTTVMNKDPEILSWT-IPPSIEKTS 6800

Query: 938  LTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIA 997
             +++  + +P +T  PVS     T+ T PS          P++ L +P+    T T+   
Sbjct: 6801 FSSS-LMPSPAMTSPPVSSTLPKTIHTTPS----------PMTSLLTPSLVMTTDTL--- 6846

Query: 998  DSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAA 1057
                    P   T    N    +HE  TT+  TT + A    HP  +          AA 
Sbjct: 6847 -----GTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAM---HPSTS---------TAAT 6889

Query: 1058 SLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA--TTATSNMAGQHGCSNPPCETHETG 1115
            ++ T++ G  + S V   S     T    TT+T   TT +++M+     +    E+  + 
Sbjct: 6890 NVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSL 6949

Query: 1116 TTNTATTAMSSVGANHQRDARRACA---AGTPAVIRISVATGALEAAQGSKSQCQTRQTS 1172
            T     T++S   A+   D     +    GT A +  +  T +   +    SQ       
Sbjct: 6950 TPGLRETSISQ-NASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPGPSQSTVLPEI 7008

Query: 1173 ATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR 1232
            +T T   + A+     +  +  P+     G  S   + L   ++K +  + S       R
Sbjct: 7009 STRTMTRLFASPTMTESAEMTIPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTL---TQR 7065

Query: 1233 HSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCP---SATVTQVC 1289
              H+  T  M+R   G    + +P  E     +PS+  ++ +L A   P   S+T+    
Sbjct: 7066 FPHSEMTTLMSRGP-GDMSWQSSPSLE-----NPSSLPSLLSLPATTSPPPISSTLPVTI 7119

Query: 1290 SNPPCETHETGTTNTATTSNA--GSAQRVCSNPPCETHET--------GTTHT----ATT 1335
            S+ P       T++  TT++    S + V S+PP  +H +         TT+T     +T
Sbjct: 7120 SSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPST 7179

Query: 1336 ATSNGGTGQPEGGQQPPAGRPCETHQTTSTG----------TTMSVSVGALLPDATSSHR 1385
             T+      P  G + P+    ++  + +T           TT+++S    L  +     
Sbjct: 7180 NTAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKE 7239

Query: 1386 TV--------ESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTA-TTV 1436
            ++        E+G  V  + ++   A  + ++   T  +       +  T  + +A +T+
Sbjct: 7240 SISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTM 7299

Query: 1437 TSNMSSNQ-----DPPPAASDQGEVE-STQGDSVNITSSSAITTTVSSTLTRAVT--TVT 1488
               +S+ +        P  ++  E+   TQ      TS S  T   S+T +  +T  T+T
Sbjct: 7300 LPEISTTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMT 7359

Query: 1489 QSTP--------------VPGPSVPPPEE-----------LQVSPGP-RQQLPPRQLLQS 1522
            Q  P              VP PS  P EE             +SP P    LP      S
Sbjct: 7360 QRLPHSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSS 7419

Query: 1523 AS-TALMG----ESAEVLSASQTPELPAAVDLSST------------------------- 1552
            AS T+L+     ++ EVL AS  PE  +   LSST                         
Sbjct: 7420 ASVTSLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAV 7479

Query: 1553 ---GEPSSGQESAGS-----------AVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAG 1598
               G  SSG ES  S           + + T+ +       +    LS  +++ +E  + 
Sbjct: 7480 TKVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASS 7539

Query: 1599 TTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGE-PMDTSE 1657
             TT +    T EE ++   A       +T     ++    +  ++ ++ G  +  M    
Sbjct: 7540 LTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDI 7599

Query: 1658 AAATVTQAELGHLSAEGQEGQATT 1681
            +  T+ +     +  E  +   TT
Sbjct: 7600 SIGTIPRISASSVLTESAKMTITT 7623



 Score =  103 bits (258), Expect = 1e-21
 Identities = 247/1113 (22%), Positives = 403/1113 (36%), Gaps = 152/1113 (13%)

Query: 379   SLEVSWGAVATADSYLLQLQKYDIPATAATATS---PTPNPVPSVPANPPKSPAPAAAAP 435
             SL  S   V +     L L   ++  T + ATS      + VP+   +P  S        
Sbjct: 11044 SLVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVT 11103

Query: 436   AVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQAT 495
             + + +T   I +L  ++  P TT ++     V  SS  +  +    G+   L VT  +A 
Sbjct: 11104 SSRAVTSTTIPILTLSSSEPETTPSMATSHGVEASSAVLTVSPEVPGMVTSL-VTSSRAV 11162

Query: 496   TGTPLVTMRPASQAGKAPVTVTSL----PAGVRMVVPTQSAQGTVIGSSPQMSGMAALAA 551
             T T + T+  +S     P T TSL     A +   +PT +   TV G    +   +    
Sbjct: 11163 TSTTIPTLTISSD---EPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVTSLVTSSGSET 11219

Query: 552   AAAATQKIPPSSAPTVLSVPA-----GTTIVKTMAVTPGT--TTLPATVKVASSPVMVSN 604
             +A +   +  S   T+ S  A      +++V T+ V+ G   T +      A S   +  
Sbjct: 11220 SAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPR 11279

Query: 605   PATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTI-TL 663
               +R   +    + ++V+S    S+  I T    G   V     +VT+    ++ T  T+
Sbjct: 11280 TTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGIPGVL--TSLVTSSGRDISATFPTV 11337

Query: 664   VKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILK 723
              +SP      ++ +++       V +  V  +      S    T  I T     A +   
Sbjct: 11338 PESPHESEATASWVTH-----PAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEATSDFP 11392

Query: 724   LVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGA 783
              +T +   P  +  T+Q + +GT  T + I +++ S+ +P TTT    I  S   T +  
Sbjct: 11393 TITVSPDVPDMV--TSQVTSSGT-DTSITIPTLTLSSGEPETTT--SFITYSETHTSSAI 11447

Query: 784   TGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPG 843
               +  SPG      ++T+ V++SGT +     T  P +     +   T + L   P +  
Sbjct: 11448 PTLPVSPGASK---MLTSLVISSGTDS----TTTFPTLTETPYEPETTAIQLI-HPAETN 11499

Query: 844   TIL-RTVPM---GGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGG 899
             T++ RT P           PV +++  P  ++ V       TT+      + TSL  + G
Sbjct: 11500 TMVPRTTPKFSHSKSDTTLPVAITSPGPEASSAV-----STTTISPDMSDLVTSLVPSSG 11554

Query: 900   HSTSASLATPITTLGTIATLSSQVINP--TAITVSAAQTTLTAAGGLTTPTITMQP---- 953
               TS +  T   T     T ++ + +P  T+ TVS      +  G  T P++   P    
Sbjct: 11555 TDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDT 11614

Query: 954   -VSQPTQVTLITAPSGVEAQPVHDLPVSILASPT-TEQPTATVTIADSGQGDVQPGTVT- 1010
                 PT     + P  V +Q       +  A PT T  P    T A S      PGT T 
Sbjct: 11615 RSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSA---THPGTQTG 11671

Query: 1011  ------LVCSNPP-----CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASL 1059
                    V S+ P       TH   T+   + T  +     P  T V     R EA++++
Sbjct: 11672 FTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAV 11731

Query: 1060  VTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNT 1119
             +T+              +P      T    ++  ATS        +  P  TH  G    
Sbjct: 11732 LTTI-------------SPGAPEMVTSQITSSGAATS--------TTVPTLTHSPGMPE- 11769

Query: 1120  ATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMT 1179
              TTA+ S    H R         +    ++S  T +L    G+++      T  TS+  T
Sbjct: 11770 -TTALLS---THPRTETSKTFPASTVFPQVSETTASLTIRPGAETS-TALPTQTTSSLFT 11824

Query: 1180  VMATG-APCSAGPLLGPS-------MAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAG 1231
             ++ TG +     P   P        ++  PG  +   +  + LS    L       L A 
Sbjct: 11825 LLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLS----LGLLETTGLLAT 11880

Query: 1232  RHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPST--TVTVTALEALLCPSATVTQVC 1289
               S   ST+ +T +        ++P    L   S +T    TVT+      PS T     
Sbjct: 11881 SSSAETSTSTLTLT--------VSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSV--- 11929

Query: 1290  SNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSN-GGTGQPEGG 1348
               P      TGTT T   S           PP  +H  G + T    T+    T     G
Sbjct: 11930 GPPEFSRTVTGTTMTLIPSE-------MPTPPKTSHGEGVSPTTILRTTMVEATNLATTG 11982

Query: 1349  QQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALL 1408
               P   +         T TT +   G+L    T+       G+   A+ SVT +      
Sbjct: 11983 SSPTVAK---------TTTTFNTLAGSLFTPLTT------PGMSTLASESVTSRTS---- 12023

Query: 1409  APFPTQRVCSNPPCETHETGTTHTATTVTSNMS 1441
               +  +   S          T  T+T VTS  S
Sbjct: 12024 --YNHRSWISTTSSYNRRYWTPATSTPVTSTFS 12054



 Score =  101 bits (252), Expect = 7e-21
 Identities = 268/1280 (20%), Positives = 456/1280 (35%), Gaps = 186/1280 (14%)

Query: 401  DIPATAATATSPTPNPVPSVPANPPKSPAPAAA---APAVQPLTQVGI-TLLPQAAPAPP 456
            + P  +A +TS      P    + P++ A +     A +V  L++  +   +    P P 
Sbjct: 2089 EFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPM 2148

Query: 457  TTTTIQVLPTVPGSSISVPT--AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPV 514
              T+   +  +   S + P+   A + G      ++ P   T   LV+ R      K P 
Sbjct: 2149 AITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLP---TSESLVSFR----MNKDPW 2201

Query: 515  TVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGT 574
            TV S+P G     PT + + ++  +S    G++ +A+    T      S PTV   P+  
Sbjct: 2202 TV-SIPLGSH---PTTNTETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPD 2257

Query: 575  TIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIIT 634
            T V T++  P  TT   + +  SS   +++  T  +        +S  S   T   P IT
Sbjct: 2258 TEVTTISHFPEKTT--HSFRTISS---LTHELTSRVTPIPGDWMSSAMSTKPTGASPSIT 2312

Query: 635  VHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQT 694
            + +  T+T A        +    T+T T                     +S+     V+T
Sbjct: 2313 LGERRTITSAAPTTSPIVLTASFTETST---------------------VSLDNETTVKT 2351

Query: 695  SAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASG--AGTKPTILG 752
            S +     T  +     +   L   +I    ++ D   T  I+ T  SG  A + P++  
Sbjct: 2352 SDILDARKTNELPSDSSSSSDLINTSIAS--STMDVTKTASISPTSISGMTASSSPSLFS 2409

Query: 753  ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGT---- 808
                   T+   T T       S   +  G + V  +P    P T IT  V TS      
Sbjct: 2410 SDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFT-ITHPVETSSALLAW 2468

Query: 809  GAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGT--------------ILRTVPMGGV 854
              P +  + +    T  G+   +   +  +   PGT               L+T P G  
Sbjct: 2469 SRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEA 2528

Query: 855  RLVTPVTV---SAVKPAVTTLVVKGTTGVTTLGTVT-----------GTVSTSLAGAGGH 900
              +   T+   +A  P ++  VV G++  +    +T            T +T  +GA   
Sbjct: 2529 HSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWE 2588

Query: 901  STSASLATPITTLGTIATLSSQVINPTAI---TVSAAQTTLTAAGGLTTPTITMQPVSQP 957
            +++   +  + T  +  TL+S+++    I   TVS   +   + G L+  +        P
Sbjct: 2589 TSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTP 2648

Query: 958  TQVTLITAPSGVEAQPVHDLPVSILASPTT-EQPTATVTIADSGQGDVQPGTVTLVCSNP 1016
                  T P+   A      P+  +AS +    P  T+T++++  GD     V    SNP
Sbjct: 2649 AIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGD---ALVLKTVSNP 2705

Query: 1017 PCETHETGTTNTATTTVVANLGGHPQPTQ-VQFVCDRQ---EAAASLVTSTV-GQQNGSV 1071
              +    G T    T        HP  T   + V  R    E + ++  ST+     GS+
Sbjct: 2706 --DRSIPGITIQGVTESPL----HPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTTGSL 2759

Query: 1072 VRVCSNPPCETH---------ETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTAT- 1121
            V   S+   ET          E  +    TT +  MA   G  +    TH TGT   ++ 
Sbjct: 2760 VFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSG--STHSTGTKTFSSL 2817

Query: 1122 ---------TAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTS 1172
                     TAMS +  N     +     G P V   S  +G L     S S  +    +
Sbjct: 2818 PLTMNPGEVTAMSEITTNRLTATQSTAPKGIP-VKPTSAESGLLTPVSASSSPSK----A 2872

Query: 1173 ATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGR 1232
              S T      G P S    L    +  P         L   S+ +     S+  +P   
Sbjct: 2873 FASLTTAPPTWGIPQST---LTFEFSEVP--------SLDTKSASLPTPGQSLNTIPDSD 2921

Query: 1233 HSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNP 1292
             S A  ++++++S       RM    +++   S  +T      E     SA+ +     P
Sbjct: 2922 ASTA--SSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEG----SASPSMAGHEP 2975

Query: 1293 PCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPP 1352
               T  TG    A+ S +        +P   +    +T  A+  T+   TGQ        
Sbjct: 2976 RVPTSGTGDPRYASESMS------YPDPSKASSAMTSTSLASKLTTLFSTGQ-------- 3021

Query: 1353 AGRPCETHQTTSTGTTMSVSVGALLPDATSSHRT-VESGLEVAAAPSVTP--QAGTALLA 1409
            A R   +    S  T    S   L P A++S +T +  G  +A  P++    Q     L+
Sbjct: 3022 AARSGSSSSPISLSTEKETSF--LSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLS 3079

Query: 1410 PFPTQRVCSNPPCE-------THETGTTHTATTVTSNMSSN-------QDPPPAASDQGE 1455
            P  T  +    P E         E GTT    T+T   S           P    + +  
Sbjct: 3080 PTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKS 3139

Query: 1456 VESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEE-----LQVSPGP 1510
               T   S+++ + +++  T   TL   +   +Q+         P EE        SPG 
Sbjct: 3140 SPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAGTSPGS 3199

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLSAS--QTPELPAAVDLSSTGEPSSGQESA---GSA 1565
             +     +++ S   ++  E    +  S  +TPE    V + +T EP + Q +A   GS 
Sbjct: 3200 PEMSTTLKIMSSKEPSISPEIRSTVRNSPWKTPE--TTVPMETTVEPVTLQSTALGSGST 3257

Query: 1566 VVATVVVQPPPPTQSEVDQL 1585
             ++ +      PT+S  + +
Sbjct: 3258 SISHLPTGTTSPTKSPTENM 3277



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 312/1531 (20%), Positives = 543/1531 (35%), Gaps = 274/1531 (17%)

Query: 405  TAATATSPTPNPVPS---VPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTI 461
            T   A  P+ N   S   +P++  +SP+ A A       T            +P   T+ 
Sbjct: 7170 TNTEAVHPSTNTAASNVEIPSSGHESPSSALADSETSKAT------------SPMFITST 7217

Query: 462  QVLPTVPGSSISVPTAARTQ-----GVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTV 516
            Q   TV  S+      +R Q      +   L+ TG    T + + T    S+      T 
Sbjct: 7218 QEDTTVAISTPHFLETSRIQKESISSLSPKLRETGSSVETSSAIETSAVLSEVSIGATTE 7277

Query: 517  TSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTI 576
             S          T S++ ++ GS+      + +    + T+KI       +L+  +  TI
Sbjct: 7278 IS------RTEVTSSSRTSISGSAE-----STMLPEISTTRKIIKFPTSPILAESSEMTI 7326

Query: 577  VKTMAVTPGTTTLPA-TVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635
             KT    PG+T+    T+  +++P +V   +T   +   +++ T VS       RP    
Sbjct: 7327 -KTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPHSEITTLVSRGAGDVPRPSSLP 7385

Query: 636  HKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTS 695
             +  +   +Q +         V+ T+     P S    SA +++L     V  T+ +  S
Sbjct: 7386 VEETSPPSSQLSLSAMISPSPVSSTL-----PASSHSSSASVTSLLTPGQVKTTEVLDAS 7440

Query: 696  AVTGQAS-------------TGPVTQIIQTKGPLPAGTILKLVTSADG--KPTTIIT--- 737
            A    +S             T  VT   +   P     + K+ TS+ G   P++++    
Sbjct: 7441 AEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVGTSSSGHESPSSVLPDSE 7500

Query: 738  TTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPIT 797
            TT+A+ A    +I+G +SVS  T     T  I++ P S++ T+   T  +    + +   
Sbjct: 7501 TTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTRLRETSTSEETSLATEAN 7560

Query: 798  IITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLV 857
             + +KV    TGA  ++        +     G  Q           T+ + + +G +   
Sbjct: 7561 TVLSKV---STGATTEVSRTEAISFSRTSMSGPEQ----------STMSQDISIGTI--- 7604

Query: 858  TPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIA 917
                     P ++   V   +   T+ T TG   ++L      + + + AT  + + T +
Sbjct: 7605 ---------PRISASSVLTESAKMTITTQTGPSESTLES----TLNLNTATTPSWVETHS 7651

Query: 918  TLSSQVINPTAITVSAAQTTLTAAGGLTTPTITM----QPVSQPTQVTLITAPSGVEAQP 973
             +     +P   T           GG++ P+        P S P  +  +T+P  V    
Sbjct: 7652 IVIQGFPHPEMTTSMG-----RGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTF 7706

Query: 974  VHDLPVSIL--ASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTT--NTA 1029
            +  +P S L   S  T  P  T  I  +     +PGT +   S+    +HE  TT  +TA
Sbjct: 7707 LAHIPPSPLPVTSLLTSGPATTTDILGT---STEPGTSS--SSSLSTTSHERLTTYKDTA 7761

Query: 1030 TTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTN 1089
             T  V     HP                ++ T++ G ++ S V   S+P C T   G T+
Sbjct: 7762 HTEAV-----HP---------STNTGGTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTS 7807

Query: 1090 TATTA-----TSNMAGQHGCSNPPCETHETGTTNTAT-TAMSSV------GANHQRDARR 1137
              T+      T  +  +   S  P     +G+  T++ T MS+V      GA  +     
Sbjct: 7808 VLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKED 7867

Query: 1138 ACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPS- 1196
              +   PA   IS        +  S S   T     T  T T    GA       L  S 
Sbjct: 7868 VTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHT-SPLGATTQGTSTLDTSS 7926

Query: 1197 -----MAREPGGRSPAFVQLAPLSSK----VRLSSPSIKDLPAGRHSHAVSTAAMTRSSV 1247
                 M      +  +  Q++ L  +    V   SP + +      S   S A  + S V
Sbjct: 7927 TTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPV 7986

Query: 1248 GAGEPRM-----APVCESLQGGSPSTT-------VTVTALEALLCPSATVTQVCSNPPCE 1295
             +  P        PV   L  G   TT         VT   A L  ++      S    +
Sbjct: 7987 SSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEILATSEVTTD 8046

Query: 1296 THETGTTNTATTSNAGS------------AQRVCSNPPCETHETGTTHTATTATSNGGTG 1343
            T +T  ++  T ++ G+            A    S        T T    + +TS  G  
Sbjct: 8047 TEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVSTSTPGFF 8106

Query: 1344 QPEGGQQPPAG------RPCETHQTTSTGTTMS-----VSVGALL----PDATSSHRTVE 1388
            +    Q  P        R   + + TS  T MS     V  GA       + TSS RT  
Sbjct: 8107 ETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTEVTSSSRTSI 8166

Query: 1389 SGLEVAAAPSVTPQAGTALLAPFPTQRVC-----------SNPPCETHETGTT------- 1430
            SG    A  +V+P+  T  +   PT  +            ++PP  T E+  T       
Sbjct: 8167 SGF---AQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTP 8223

Query: 1431 ---HTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTV 1487
                T +TVT   S ++     +   G++      SV  TSS++   ++ +T + +  + 
Sbjct: 8224 NWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSS 8283

Query: 1488 TQSTPVPGPSVP-----------PPEELQVSPGP-------------------------- 1510
            T     P  S+P             + + +S  P                          
Sbjct: 8284 TLVEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTE 8343

Query: 1511 RQQLPPRQLLQSASTALMGESAE--VLSASQTPELPAAVDLSST-GEPSSGQESAGSAVV 1567
              Q      + +  T++ G  ++  VLS S+TP+  + +  + T GE S    ++     
Sbjct: 8344 DMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTMGETSVSISTSDFFET 8403

Query: 1568 ATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQA--- 1624
            + + ++P     S + + S  + + +  +  T    V      E++ T    +   +   
Sbjct: 8404 SRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSG 8463

Query: 1625 ---------AATEEAQALAIQAVL-QAAQQAV-MGTGEPMDTSEAAATVTQAELGHLSAE 1673
                      +TE    L+   ++ ++A+ A+ + TG P  TSE   T+  +     S  
Sbjct: 8464 PDQFTISPDISTEAITRLSTSPIMTESAESAITIETGSPGATSEGTLTLDTSTTTFWS-- 8521

Query: 1674 GQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPT--EALAPADSLNDPAIESN 1731
               G  +T     +  E+  L     +           LP+  EA + + SL+ PA+ S 
Sbjct: 8522 ---GTHSTASPGFSHSEMTTL-----MSRTPGDVPWPSLPSVEEASSVSSSLSSPAMTS- 8572

Query: 1732 CLNELAGTVPSTVALLPS--TATESLAPSNT 1760
                   T+P +++  P   TA  +L P  T
Sbjct: 8573 --TSFFSTLPESISSSPHPVTALLTLGPVKT 8601



 Score = 95.1 bits (235), Expect = 6e-19
 Identities = 354/1655 (21%), Positives = 588/1655 (35%), Gaps = 338/1655 (20%)

Query: 376  NTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSP---TPNPVPSVPANPPKSPAPAA 432
            +TN+  +  GA A+++S         I  T A+   P   TP   PS+  +   S A  A
Sbjct: 1245 STNTPSIHLGAHASSES------PSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMA 1298

Query: 433  AAPAVQPL------TQVGITLLPQA---APAPPTTTTIQVLPTVPGSSISVPTAARTQGV 483
             +    P       T  G T  P        P  T++ QV      +  SV T   T+  
Sbjct: 1299 YSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDTSSAQV-----STPHSVRTLRTTENH 1353

Query: 484  PAVLKVTGPQATTGTPLVTMRP--ASQAGKAPVTVTSLPAGVRMVVP----------TQS 531
            P     T P A +G+P ++  P   S A KA     +     ++             TQS
Sbjct: 1354 PKTESAT-PAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQS 1412

Query: 532  AQG---TVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTT 588
            A G    VI +SP +      ++    T  +P    P VL+    TTI   MA    T+ 
Sbjct: 1413 APGPVSVVIPTSPTIG-----SSTLELTSDVP--GEPLVLAPSEQTTITLPMATWLSTSL 1465

Query: 589  LPATVKVASSPVMVSNPATRM--------LKTAAAQVGTS---VSSATNT---------- 627
               T ++AS+ + +S+P++ M        + T + ++  S    S+  NT          
Sbjct: 1466 ---TEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLG 1522

Query: 628  ----------STRPI--ITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSA 675
                      +T PI  +T   +  +  + QAQ   +     T     +K   S+P  SA
Sbjct: 1523 IRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPA-SA 1581

Query: 676  LISNLGKVMSVVQTKPVQTSAVTG--QASTGPVTQIIQTKGPLPAGTILKLVTSADGKPT 733
              S+L +V   + T+   +S  T   + ST  +++ I+T GP          T+    P 
Sbjct: 1582 SPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIET-GP----------TNIQSTPP 1630

Query: 734  TIITTTQASGAGTKPTILGISSVSPSTTKPGTTTI---IKTIPMSAIITQAGATG--VTS 788
               TTT +S +G     LGI+ +   T+ P  T+    ++    +A ++ AG  G  VTS
Sbjct: 1631 MDNTTTGSSSSGVT---LGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTS 1687

Query: 789  SPG---------IKSPITIITTKVMT-SGTGAPAKI-------ITAVPKIATGHGQQGVT 831
            +PG         + S ++  TT+ +T S  G+  ++       +++  + +   G Q  T
Sbjct: 1688 APGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMST 1747

Query: 832  QVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAV-KPAVTTLVVKGTTGVTTLGT----- 885
             + L  +P  P            + VT V  S + K +  T     T   T LG+     
Sbjct: 1748 SIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTG 1807

Query: 886  -------------------VTGTVSTSLAGA-----------GGHSTSASLATPITTLGT 915
                               VT  +S +L+ A           G H++SA       +L T
Sbjct: 1808 KEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNT 1867

Query: 916  IATLSSQVINP---------------TAITVS------------------AAQTTLTAAG 942
              T +S++ N                T++T +                   A+TTLT+  
Sbjct: 1868 GVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTP 1927

Query: 943  G-----LTTP-----------------------TITMQPVSQPTQVTLITAPSGVEAQPV 974
            G     LT P                        +T  P++ PT V   T       QP+
Sbjct: 1928 GNRAISLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPL 1987

Query: 975  HDL---PVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATT 1031
            H +    VS+    T    +  V+ + + +  V  G+ T   S+P         ++ +  
Sbjct: 1988 HAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSST---SSP--------YSSASLE 2036

Query: 1032 TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            ++ + +      T   +         +  ++++ +   S     SNP   T E    + A
Sbjct: 2037 SLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAA 2096

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            +T+ +         NP  ETH  G  NTA + +++       DA              S 
Sbjct: 2097 STSAAKQ------RNPETETH--GPQNTAASTLNT-------DA--------------SS 2127

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             TG  E   G+    +     A ++   V    +  +A P LG   A   G +    + L
Sbjct: 2128 VTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLG--TASSAGTKLTRTISL 2185

Query: 1212 APLSSKVRL---SSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPST 1268
                S V       P    +P G H    +  ++  +S  AG P ++ V   +       
Sbjct: 2186 PTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNS--AGPPGLSTVASDVIDTPSDG 2243

Query: 1269 TVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTAT---TSNAGSAQRVCSNPPCETH 1325
              ++  +     P   VT +   P   TH   T ++ T   TS          +    T 
Sbjct: 2244 AESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTK 2303

Query: 1326 ETGTTHTAT-----TATSNGGTGQP---EGGQQPPAGRPCETHQTTSTGTTMSVSVGALL 1377
             TG + + T     T TS   T  P          +    +   T  T   +       L
Sbjct: 2304 PTGASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNEL 2363

Query: 1378 PDATSSHRTV------ESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTH 1431
            P  +SS   +       S ++V    S++P + + + A        S+ P     T TT 
Sbjct: 2364 PSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRP--QVPTSTTE 2421

Query: 1432 TATTVTSNMSSNQDPPPAASDQGEVEST----------QGDSVNITSSSAITT--TVSST 1479
            T T  + ++SSN       S+ G   ST          +  S  +  S  + T  T+ ST
Sbjct: 2422 TNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVST 2481

Query: 1480 LTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSA-- 1537
             T +    T S  V   SVP P     S G    LP    L+   T+  GE+  +L++  
Sbjct: 2482 DTASGENPTSSNSVV-TSVPAP-GTWTSVGSTTDLPAMGFLK---TSPAGEAHSLLASTI 2536

Query: 1538 ----SQTPELPAAV--DLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQEL 1591
                + TP L AAV    S+T E S    S   A+ ++      P + +  +  + P+ L
Sbjct: 2537 EPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQTPTTPTSGANWETSATPESL 2596

Query: 1592 MAEAQAGTTTL----MVT--------GLTPEELAVTAAAEAAAQAAATEEAQALAIQAVL 1639
            +   +   TTL    +VT           P +   T     A+      +  A+ + A  
Sbjct: 2597 LVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATE 2656

Query: 1640 QAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQ 1699
              +  A      P+ T  + +  T  E     +E   G A  +  V         +  Q 
Sbjct: 2657 PTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQG 2716

Query: 1700 LQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSN 1759
            + E+         P++ +AP ++  + +I        AGT  S V    S  +E+ A   
Sbjct: 2717 VTESPLHPSSTS-PSKIVAPRNTTYEGSITVALSTLPAGTTGSLVFSQSSENSETTA--- 2772

Query: 1760 TFVAPQPVVVASPAKLQAAAT--LTEVANGIESLG 1792
                    +V S A L+ A+   LT  + G+ S G
Sbjct: 2773 --------LVDSSAGLERASVMPLTTGSQGMASSG 2799



 Score = 94.7 bits (234), Expect = 8e-19
 Identities = 310/1528 (20%), Positives = 535/1528 (35%), Gaps = 218/1528 (14%)

Query: 405  TAATATSPTPN-PVPSVPANPP--KSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTI 461
            T A +T+   N PV   PA      S  P    P+   L    + L P+  P     T++
Sbjct: 195  TFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSSFLDLSPKGTPNSRGETSL 254

Query: 462  QVLPTVPGSSISVP-----------TAARTQGVPAVL--KVTGPQATTG----TPLVTMR 504
            +++ +  G   S P           T+A      +VL  K++     +G    +PL    
Sbjct: 255  ELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGV 314

Query: 505  PASQAGKAP-------VTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQ 557
            P ++A   P       +T+++       V  T S+ GT   S+ Q +       A A T 
Sbjct: 315  PEARASTMPNSAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETM 374

Query: 558  KIPPSSAPTVLSVPAGTTIVKTMAV----TPGT---TTLPATVKVASSPVMVSNPATRML 610
             IP             T I KT+A     +PGT   T+  A    + S  +VS       
Sbjct: 375  DIP------------STHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHH 422

Query: 611  KTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVG--GVTKTITLVKSPI 668
             T+    G       NTS  P+       T    +++++  T+V   G T   + ++SP 
Sbjct: 423  STS----GKETEGTLNTSMTPL------ETSAPGEESEMTATLVPTLGFTTLDSKIRSPS 472

Query: 669  SVPGGSALI------SNLGKVMS---------VVQTKPVQTSAVTGQASTGPVTQIIQTK 713
             V             S  G+  S         +++     TS  +   S     Q  + +
Sbjct: 473  QVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDILRATTSSTSKASSWTSESTAQQFSEPQ 532

Query: 714  GPLPAGTILKLVTSADGKPTTI---ITTTQASGAGTKPTILGISSVSPSTTKP------- 763
                  T   + T      T++   ITT+  S       + G +++  S+TK        
Sbjct: 533  HTQWVETSPSMKTERPPASTSVAAPITTSVPS------VVSGFTTLKTSSTKGIWLEETS 586

Query: 764  -----GTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGT---------G 809
                 G +T   T    A+ T    TG +S+ G +    ++T    +S T         G
Sbjct: 587  ADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNG 646

Query: 810  APAKIITAVPKIATGHGQQG--------VTQVV-----LKGAPGQPGTILRTVPMGGVR- 855
             P  +  AV K A G    G        V+ V+     L+ +  + GT L   P+     
Sbjct: 647  VPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSLQSSAFREGTSLGLTPLNTRHP 706

Query: 856  LVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGT 915
              +P   SA    ++T +   ++       V+ T + S      H  ++S+ T    + T
Sbjct: 707  FSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFS-----HHKATSSITTGTPEIST 761

Query: 916  IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVH 975
                SS V++  ++T+S A T+       T+P     P  + T  +++T  +  E     
Sbjct: 762  KTKPSSAVLS--SMTLSNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSP 819

Query: 976  DL-PVSILASPTTEQPTATVTIADSGQGDV-----------QPGTVTLVCSNPPCETHET 1023
            ++ P   L S ++E P+     + SG                 G  T   SNP     ET
Sbjct: 820  NIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEETEETSNPSVSQPET 879

Query: 1024 GTTNTATTTVVANLGGHPQPTQVQFVC-DRQEAAASLVTSTVGQQNGSVVRVCSNP-PCE 1081
              +   TT    ++     PT   +     Q +++ LV+      + SV     +  P  
Sbjct: 880  SVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKI 939

Query: 1082 THETGTTNTATTATSNMAGQHGCSNPPCET-------HETGTTNTATTAMSSVGANHQRD 1134
            +H TGT   AT + +N    +  + P   T        +TG  +  TT  +S        
Sbjct: 940  SHLTGT---ATMSQTNRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTS-------- 988

Query: 1135 ARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLG 1194
                 A    A + +S  T    ++  + S  +   T  T+ T     + A  S    +G
Sbjct: 989  -----ATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIG 1043

Query: 1195 PSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTA-AMTRSSVGAGEP- 1252
                 E  GR    +  + L      SS +  D    + S ++S + + +  + G+  P 
Sbjct: 1044 KGYITE--GR----LDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPG 1097

Query: 1253 RMAPVCESLQGG-----SPSTTVTVTALEALLCPSATVTQVCSNPPCETHET-------- 1299
            R +   ++         S   T+      + L P  T T   S  P     T        
Sbjct: 1098 RTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPDPGSARSTWLGILSSS 1157

Query: 1300 --GTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPC 1357
                T   T S+  S QRV ++   +T ET   +     ++   T               
Sbjct: 1158 PSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTL 1217

Query: 1358 ETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAA-----APSVTPQAGTALLAPFP 1412
                T S  T++  S G L   +T    T    + + A     +PS       +++ P  
Sbjct: 1218 VPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKP-G 1276

Query: 1413 TQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAI 1472
            +    + P  ETH     H +T   +  SS   P   A  +    ST   +  IT++   
Sbjct: 1277 SYTPLTFPSIETH----IHVSTARMA-YSSGSSPEMTAPGETNTGSTWDPTTYITTTDPK 1331

Query: 1473 TTTVSSTLT-RAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGES 1531
             T+ +   T  +V T+  +   P      P     SP             S+S  L   +
Sbjct: 1332 DTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKI-----------SSSPNLTSPA 1380

Query: 1532 AEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLS--LPQ 1589
             +  + + T E    +  +   E SSG E+  +    +VV+   P   S   +L+  +P 
Sbjct: 1381 TKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPG 1440

Query: 1590 ELMAEAQAGTTTL---MVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAV 1646
            E +  A +  TT+   M T L+       A+ +    + ++  +       +   + +  
Sbjct: 1441 EPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTPSHELS 1500

Query: 1647 MGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIV-LTQQELAALVQQQQLQEAQA 1705
                +        +T     LG + + G+ G  TT+PI  LT    + +    Q Q+  +
Sbjct: 1501 KSEADTSAIRNTDSTTLDQHLG-IRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLS 1559

Query: 1706 QQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQ 1765
                    T++L    S+   A  S+ L E+   +  T     S AT    PS   ++ +
Sbjct: 1560 ATMSPTHVTQSLKDQTSIPASASPSH-LTEVYPEL-GTQGRSSSEATTFWKPSTDTLSRE 1617

Query: 1766 PVVVASPAKLQAAATLTEVANGIESLGV 1793
              +   P  +Q+   +     G  S GV
Sbjct: 1618 --IETGPTNIQSTPPMDNTTTGSSSSGV 1643



 Score = 91.7 bits (226), Expect = 7e-18
 Identities = 271/1351 (20%), Positives = 461/1351 (34%), Gaps = 194/1351 (14%)

Query: 456   PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVT 515
             P TT+  V  T+P S  S   +  +   P ++K T      GT L        +     T
Sbjct: 10028 PVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSL--------SPNLSGT 10079

Query: 516   VTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT 575
                + A   +   T+    +   SS  ++ +   ++       +   S P+  + P GT 
Sbjct: 10080 SVEILAASEVTTDTEKIHPS---SSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGTP 10136

Query: 576   IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635
                +MA T  +T++PA  +         +  T   +     + TS  + TNT + P  T 
Sbjct: 10137 --SSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSPGSTH 10194

Query: 636   HKSGTVT---------------VAQQAQVVTTVV------GGVTKTITLVKSP-----IS 669
                 + T                +Q  ++   ++        +T++  +   P     +S
Sbjct: 10195 LLQSSKTDFTSSAKTSSPDWPPASQYTEIPVDIITPFNASPSITESTGITSFPESRFTMS 10254

Query: 670   VPGGSALISN----LGKVMSVVQTKPVQTSAVTGQASTG----------PVTQIIQTKGP 715
             V   +  +S       + +S     P  + A+T  A+TG          P ++     G 
Sbjct: 10255 VTESTHHLSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAISGSGSPFSRTESGPGD 10314

Query: 716   LPAGTILKLVTSADGKP--TTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIP 773
                 TI + + S+   P  ++  TTT +S   T P +  I+S S +  +  T+   ++  
Sbjct: 10315 ATLSTIAESLPSSTPVPFSSSTFTTTDSS---TIPALHEITSSSATPYRVDTSLGTESST 10371

Query: 774   MSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQ-QGVTQ 832
                 +        +S PG  S   I+ T++  S           VP ++T   +  G+ +
Sbjct: 10372 TEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGIME 10431

Query: 833   VVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVST 892
              + K  P +          G +R V     S    +   L   GT  + T  T   T +T
Sbjct: 10432 HITK-IPNE------AAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTT 10484

Query: 893   SLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAI-----------------TVSAAQ 935
             +L      + + S+ TP  TLGT+  L++ +   + I                 T S+  
Sbjct: 10485 ALKTTSRATLTTSVYTP--TLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLA 10542

Query: 936   TTLTAAGGLTTPTITMQPVSQPTQVTL-ITAPSGVEAQPVHDLPVSILASPTTEQPTATV 994
             T+L A      P  T    ++ ++ T  + + SG E  PV    +  L   ++E  T   
Sbjct: 10543 TSLGAETSTALPRTTPSVFNRESETTASLVSRSGAERSPV----IQTLDVSSSEPDTTAS 10598

Query: 995   TIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQE 1054
              +    +      T+  V    P   H    T ++T T          PT +       +
Sbjct: 10599 WVIHPAE------TIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNIS--PSELD 10650

Query: 1055  AAASLVTSTVGQQNGSVVRVCSNPPCE--------THETGTTNT--------------AT 1092
             A   LVT + G    +     +  P E        TH   T++T              AT
Sbjct: 10651 ALTPLVTIS-GTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDAT 10709

Query: 1093  TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRD-ARRACAAGTPAVI---- 1147
              + +   G    S  P  T   G  +  T+ ++S G +          + G P  I    
Sbjct: 10710 PSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLV 10769

Query: 1148  -------RISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE 1200
                      ++ T  +  A            +A ++T     T +P    P    S+   
Sbjct: 10770 THPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNRALTNSP--GEPATTVSLVTH 10827

Query: 1201  PGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSH-AVSTAAMTRSSVGAGEPRMAPVCE 1259
             P   SP      P ++ +   S S    P+   SH A S++A+   +V    P +     
Sbjct: 10828 PAQTSPT----VPWTTSIFFHSKS-DTTPSMTTSHGAESSSAVPTPTVSTEVPGVVTPLV 10882

Query: 1260  SLQGGSPSTTVTVTAL---EALLCPSATVT---QVCSNPPCETHETGTTNTATTSNAGSA 1313
             +      STT+ +  L   E    PS   +   +  S  P  T   G     T+    S 
Sbjct: 10883 TSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSR 10942

Query: 1314  QRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSV 1373
                 +  P  T   G   T  +  ++ GT   E G   P   P      TS   +     
Sbjct: 10943 AVTSTTIPILTFSLGEPETTPSMATSHGT---EAGSAVPTVLPEVPGMVTSLVASSRAVT 10999

Query: 1374  GALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTA 1433
                LP  T S             P  TP   T+  A        S  P  + E     T+
Sbjct: 11000 STTLPTLTLS----------PGEPETTPSMATSHGA-----EASSTVPTVSPEVPGVVTS 11044

Query: 1434  TTVTSNMSSNQDPPPAASDQGEVEST--QGDSVNITSSSAI-TTTVSSTLTRAVT-TVTQ 1489
                +S+  ++   P      GE+E+T     S    +SSA+ T TVS  ++  VT  VT 
Sbjct: 11045 LVTSSSGVNSTSIPTLILSPGELETTPSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTS 11104

Query: 1490  STPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDL 1549
             S  V   ++P    L +S    +  P       A++  +  S+ VL+ S  PE+P  V  
Sbjct: 11105 SRAVTSTTIP---ILTLSSSEPETTP-----SMATSHGVEASSAVLTVS--PEVPGMVTS 11154

Query: 1550  SSTGEPSSGQESAGSAVVATVVVQPPPP-------TQSEVDQLS-LPQELMAEAQAGTTT 1601
               T        +  S  + T+ +    P       T SE   +S +P   ++    G  T
Sbjct: 11155 LVT-----SSRAVTSTTIPTLTISSDEPETTTSLVTHSEAKMISAIPTLAVSPTVQGLVT 11209

Query: 1602  LMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAA- 1660
              +VT    E  A +    A++Q    +   A              + TGEP         
Sbjct: 11210 SLVTSSGSETSAFSNLTVASSQPETIDSWVAHPGTEASSVVPTLTVSTGEPFTNISLVTH 11269

Query: 1661  -TVTQAELGHLSAEGQEGQATTIPIVLTQQE 1690
                + + L   ++     +  T+P  +T  E
Sbjct: 11270 PAESSSTLPRTTSRFSHSELDTMPSTVTSPE 11300



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 277/1325 (20%), Positives = 494/1325 (37%), Gaps = 192/1325 (14%)

Query: 402  IPATAATATSPTPNPVPSVPANP--------PKSPAPAAAAPAVQPLTQVGITLLPQAAP 453
            + +T   + S +P PV S+  +          KS  P   +PA    T V I      A 
Sbjct: 7986 VSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEIL-----AT 8040

Query: 454  APPTTTTIQVLPTVPGSSISVPTAARTQGVPAVL-------KVTGPQATTGTPLVTMRPA 506
            +  TT T +  P+   +   V T++      + +       KVT P   T T   T    
Sbjct: 8041 SEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTSVST 8100

Query: 507  SQAGKAPVT------VTSLPAGVRMVVPTQSAQGTVIGS--SPQMSGMAALAAAAAATQK 558
            S  G    +       +SL  G+R    T S++GT + +  S  +SG+   A A  +  +
Sbjct: 8101 STPGFFETSRIQTEPTSSLTLGLRK---TSSSEGTSLATEMSTVLSGVPTGATAEVSRTE 8157

Query: 559  I-----------------PPSSAPTVLSVPAGTTI-------VKTMAVTPGTTTLPA-TV 593
            +                 P +S  T+  +P  + +       +KT    PG+T     TV
Sbjct: 8158 VTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTV 8217

Query: 594  KVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTV 653
             ++++P  V   +T   + + +++ T VS +      P  +  +  +   +  +   TT 
Sbjct: 8218 DISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTS 8277

Query: 654  VGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTK 713
               V+ T+       S+P  S L   L     V+ T  +  S   G +ST  ++     +
Sbjct: 8278 PSPVSSTLVEDFPSASLPVTSLLNPGL-----VITTDRMGISREPGTSSTSNLSSTSHER 8332

Query: 714  GPLPAGTILKLVTSADGKPTTIITTTQA----SGAGTKPTILGISSVSPSTTKPGTTTII 769
                  T+   V + D +P+T    T      SG  ++ ++L  S    +T+  GTT  +
Sbjct: 8333 ----LTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETPKATSPMGTTYTM 8388

Query: 770  KTIPMSAIITQAGATG---VTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHG 826
                +S   +    T    +  +  + S +   ++    S     + +++ VP  AT   
Sbjct: 8389 GETSVSISTSDFFETSRIQIEPTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEV 8448

Query: 827  QQGVTQVVLKGAPGQPG----TILRTVPMGGV-RLVT-PVTVSAVKPAVTTLVVKGTTGV 880
             +  T+V+        G    TI   +    + RL T P+   + + A+T  +  G+ G 
Sbjct: 8449 SR--TEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESAESAIT--IETGSPGA 8504

Query: 881  TTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTA 940
            T+ GT+T   ST+   +G HST    A+P  +   + TL S+                  
Sbjct: 8505 TSEGTLTLDTSTTTFWSGTHST----ASPGFSHSEMTTLMSRTPG--------------- 8545

Query: 941  AGGLTTPTITMQPVSQPTQV-TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADS 999
                  P  ++  V + + V + +++P+         LP SI +SP     TA +T+   
Sbjct: 8546 ----DVPWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSP--HPVTALLTL--- 8596

Query: 1000 GQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASL 1059
              G V+   +    S P  ET      ++ +  ++A           +   DR++   S 
Sbjct: 8597 --GPVKTTDMLRTSSEP--ETSSPPNLSSTSAEILAT---------SEVTKDREKIHPSS 8643

Query: 1060 VTSTVGQQNGSVVRVCSNPPCETHETGTTN-TATTATSNMAGQHGCS-NPPC--ETHETG 1115
             T  V    G+V+    +P     +  TT  T+  AT++  G    S + P   ET  T 
Sbjct: 8644 NTPVVNV--GTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQ 8701

Query: 1116 TTNTATTAMSSVGANHQRDA---RRACAAGTPAVIRISVA-TGALEAAQGSKSQCQTRQT 1171
             T++ T+ +  +  + +  +   R A  +G P      V+ T AL   + S         
Sbjct: 8702 PTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTI 8761

Query: 1172 SATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAG 1231
            S   +T T+     P +       ++  + G    +      L +  R S P        
Sbjct: 8762 SPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATH 8821

Query: 1232 RHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSN 1291
            R  H+  T  M+R       P    V ++     PS+ V+++A+ +     +T ++   +
Sbjct: 8822 RSPHSGMTTPMSRGPEDVSWPSRPSVEKT---SPPSSLVSLSAVTSPSPLYSTPSESSHS 8878

Query: 1292 PPCETHETGTTNTATTSNA--GSAQRVCSNPP---CETHETGTTHTAT-----------T 1335
             P       T     T++    S + V ++PP     + E+  T  AT           T
Sbjct: 8879 SPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENT 8938

Query: 1336 ATSNGGT---GQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLE 1392
            A +  GT    Q      P    P +      T +T+   V   +P ++   R     +E
Sbjct: 8939 AVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTIKDIVSTTIPASSEITR-----IE 8993

Query: 1393 VAAAPSVTP-QAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            + +  ++TP    T+      +    S  P +   + T     ++T  MSS++ P P  S
Sbjct: 8994 MESTSTLTPTPRETSTSQEIHSATKPSTVPYKALTSATIE--DSMTQVMSSSRGPSPDQS 9051

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPR 1511
               +  ST  + +   S+S I T  +        T+T  T  PG +      L  S    
Sbjct: 9052 TMSQDIST--EVITRLSTSPIKTESTE------MTITTQTGSPGATSRGTLTLDTS---- 9099

Query: 1512 QQLPPRQLLQSASTALMGESAEVLSA--SQTPELPAAVDLSSTGEPSSGQESAGSAVVAT 1569
                   +  + STA  G S   ++A  S+TP      D+     PS  + S+ S  +++
Sbjct: 9100 ----TTFMSGTHSTASQGFSHSQMTALMSRTPG-----DVPWLSHPSVEEASSASFSLSS 9150

Query: 1570 VVVQPPPPTQS----EVDQLSLP-QELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQA 1624
             V+    P  S     +   SLP   L+      TT L+ T   PE  +    +  +A+ 
Sbjct: 9151 PVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSSEPETSSPPNLSSTSAEI 9210

Query: 1625 AATEE 1629
             A  E
Sbjct: 9211 LAITE 9215



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 267/1350 (19%), Positives = 481/1350 (35%), Gaps = 197/1350 (14%)

Query: 397   LQKYDIPATAATATSPT-PNPVPSVPANPPKSP---APAAAAPAVQPLTQVGITLLPQAA 452
             ++K   P++  + ++ T P+P+ S P+    S      +   P +   T +  T L    
Sbjct: 8847  VEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVT 8906

Query: 453   PAPPT-----------------TTTIQVLPTVPGSSISVPTAART-----QGVPAVLKVT 490
              +PP+                 T  IQ+      + +   +A +       G+P   KVT
Sbjct: 8907  TSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVT 8966

Query: 491   GPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALA 550
              P  T+ T               +  T++PA   +      +  T+  +  + S    + 
Sbjct: 8967  SPVVTSSTI------------KDIVSTTIPASSEITRIEMESTSTLTPTPRETSTSQEIH 9014

Query: 551   AAAAATQKIPPSSAP--TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATR 608
             +A        PS+ P   + S     ++ + M+ + G +   +T+    S  +++  +T 
Sbjct: 9015  SATK------PSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTS 9068

Query: 609   MLKTAAA------QVGTSVSSATNTSTRPIITVHKSGTVTVAQQA---QVVTTVVGGVTK 659
              +KT +       Q G+  +++  T T    T   SGT + A Q      +T ++     
Sbjct: 9069  PIKTESTEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPG 9128

Query: 660   TITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTG-QASTGPVTQIIQTKGPLPA 718
              +  +  P      SA  S    VM+   + PV ++      +S+ PVT ++ T G +  
Sbjct: 9129  DVPWLSHPSVEEASSASFSLSSPVMT--SSSPVSSTLPDSIHSSSLPVTSLL-TSGLVKT 9185

Query: 719   GTILKLV-------------TSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGT 765
               +L                TSA+    T +TT       T     G +  SPS+    +
Sbjct: 9186  TELLGTSSEPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADS 9245

Query: 766   TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVM--------------TSGTGAP 811
              T   T  M           +TS+P       I T   +              TS     
Sbjct: 9246  VTTKATSSMGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPGLMETSISEETSSATEK 9305

Query: 812   AKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMG-GVRLVTPVTVSAVKPAVT 870
             + ++++VP  AT    +  T+ +       PG    T+     +  +T ++    +   T
Sbjct: 9306  STVLSSVPTGATTEVSR--TEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKEST 9363

Query: 871   TLVVK---GTTGVTTLGTVTGTVSTSLAGAGGHSTSASL--ATPITTLGTIATLSSQVIN 925
              + +    G +G T+ GT T   S++ +  G HS +      + +TT  +         +
Sbjct: 9364  DMAITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTPMSRGPEDVSWPS 9423

Query: 926   PTAITVSAAQTTLTAAGGLTTP-----TITMQPVSQPTQVTLITAPSGVEAQPVHDLPVS 980
             P ++  ++  ++L ++  +T+P     T +    S P  VT +     ++A  + D   +
Sbjct: 9424  PLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLD---A 9480

Query: 981   ILASPTTEQPTATVTIADS-GQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGG 1039
              L   TT  P   +T  +S         T  +        +H    T +AT  + ++  G
Sbjct: 9481  SLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVE--TTSATEELYSSSPG 9538

Query: 1040  HPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRV----CSNPPCETHETGTTNTATTAT 1095
               +PT+V        +    + ST    +  + R+     S+      ET T+   T++T
Sbjct: 9539  FSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQDITSST 9598

Query: 1096  SNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGA 1155
                   +    P   T E   T    ++ +S+                PA   +S+    
Sbjct: 9599  ETSTVLY--KMPSGATPEVSRTEVMPSSRTSIPG--------------PAQSTMSLDISD 9642

Query: 1156  LEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSP-----AFVQ 1210
                 + S S   T     T TT T  +        PL G SM    G  S      +  +
Sbjct: 9643  EVVTRLSTSPIMTESAEITITTQTGYSLATSQVTLPL-GTSMTFLSGTHSTMSQGLSHSE 9701

Query: 1211  LAPLSSK--VRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPST 1268
             +  L S+    LS  S + +   R S ++++  +T S        ++PV  +L   SPS+
Sbjct: 9702  MTNLMSRGPESLSWTSPRFVETTRSSSSLTSLPLTTS--------LSPVSSTLLDSSPSS 9753

Query: 1269  TVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETG 1328
              + VT   +L+ P    T    +   E   + + N ++TS    A         + H + 
Sbjct: 9754  PLPVT---SLILPGLVKTTEVLDTSSEPKTSSSPNLSSTSVEIPATSEIMTDTEKIHPSS 9810

Query: 1329  TTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVE 1388
              T  A   TS+                  E+H +    +  ++++ ++   +     TV 
Sbjct: 9811  NTAVAKVRTSSS---------------VHESHSSVLADSETTITIPSMGITSAVDDTTVF 9855

Query: 1389  SGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHET-----GTTHTATT---VTSNM 1440
             +     +     P   T  L P   +   S       ET     G   +ATT   +T  M
Sbjct: 9856  TSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYGVPTSATTEVSMTEIM 9915

Query: 1441  SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT--TVTQSTPVPGPSV 1498
             SSN+   P  SDQ    ST    +    +  IT   SS++    T  T+T     PG + 
Sbjct: 9916  SSNRIHIP-DSDQ----STMSPDI---ITEVITRLSSSSMMSESTQMTITTQKSSPGATA 9967

Query: 1499  PPPEELQVSPGP----RQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGE 1554
                  L  +  P       +PPR  L S  T LM  S E       P   +++ +  T  
Sbjct: 9968  QSTLTLATTTAPLARTHSTVPPR-FLHSEMTTLMSRSPE------NPSWKSSLFVEKTSS 10020

Query: 1555  PSS--GQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPE-- 1610
              SS        S  V++ + Q  P +   V  L  P  +       T+T   T L+P   
Sbjct: 10021 SSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKT---TDTSTEPGTSLSPNLS 10077

Query: 1611  --ELAVTAAAEAAAQAAATEEAQALAIQAV 1638
                + + AA+E          + ++A+  V
Sbjct: 10078 GTSVEILAASEVTTDTEKIHPSSSMAVTNV 10107



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 278/1361 (20%), Positives = 487/1361 (35%), Gaps = 151/1361 (11%)

Query: 457  TTTTIQVLPTVPGSSIS--VPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPV 514
            T TT  + P +  +SIS  + ++  T  VP   ++TG  ATT      +  +S       
Sbjct: 4887 TETTSSLTPKLRETSISQEITSSTETSTVP-YKELTG--ATTEVSRTDVTSSSSTSFPGP 4943

Query: 515  TVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKI----PPSSAPTVLSV 570
              +++   +     T+ +   ++  S +++         A +Q      P ++ P     
Sbjct: 4944 DQSTVSLDISTETNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIH 5003

Query: 571  PAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT---NT 627
             A T     + VT   + +P  V   S P +    +     ++ A    S+ S+T   + 
Sbjct: 5004 SAMTHGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDK 5063

Query: 628  STRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS-VPGGSALISNLGKVMSV 686
             + P+ ++  SG V +     ++ T +  VT ++    S    +   S    +  ++   
Sbjct: 5064 LSSPMTSLLTSGLVKITD---ILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPS 5120

Query: 687  VQTKPVQTSAV-TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT-----TTQ 740
            + T+     A  +G  S  P     +T    P  T   ++T+  G P    +     +++
Sbjct: 5121 INTEETNVKANNSGHESHSPALADSET----PKATTQMVITTTVGDPAPSTSMPVHGSSE 5176

Query: 741  ASGAGTKPTI-----LGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSP 795
             +    +PT      L  +S S  ++ P  T+ + +   +  IT+  +TGV SS  I +P
Sbjct: 5177 TTNIKREPTYFLTPRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTP 5236

Query: 796  ITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVR 855
                +T    + TG   ++ T+   I T   +  +T    + +P          P     
Sbjct: 5237 DHDKSTVPPDTFTGEIPRVFTS--SIKTKSAEMTIT---TQASP----------PESASH 5281

Query: 856  LVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGT 915
               P+  S      TTL   GT    T G     V T+L G G  + S     P+    +
Sbjct: 5282 STLPLDTS------TTLSQGGTHSTVTQGFPYSEV-TTLMGMGPGNVSWMTTPPVEETSS 5334

Query: 916  IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVH 975
            +++L S     +   VS+       +  L    +    +   T V   T+P  V + P +
Sbjct: 5335 VSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPESVTSSPPN 5394

Query: 976  DLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVA 1035
                  L+S T E+P    T  D+                   E     +TNTA T V  
Sbjct: 5395 ------LSSITHERP---ATYKDTAH----------------TEAAMHHSTNTAVTNVGT 5429

Query: 1036 NLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTAT 1095
            +  GH   + V  + D + + A+ + ST      + V   +    +T++  T  TA  + 
Sbjct: 5430 SGSGHKSQSSV--LADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTA--SL 5485

Query: 1096 SNMAGQHGCSNPPCETHETGT--TNTATTAMSSVGANHQRDARRACAAGTPAVIRISVAT 1153
            S    +   S     T ET T  +   T A++         +R + +      I   ++T
Sbjct: 5486 SPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDLDRPTIAPDIST 5545

Query: 1154 GALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPL-LGPSMAREPGGRSPAFVQLA 1212
            G +     S    ++ + + T+ T T  AT    S G L    S     GG      Q  
Sbjct: 5546 GMITRLFTSPIMTKSAEMTVTTQTTTPGAT----SQGILPWDTSTTLFQGGTHSTVSQGF 5601

Query: 1213 PLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTV 1272
            P S    L S +  D+ +   +  V   +   S +       +PV  +     PS+ + V
Sbjct: 5602 PHSEITTLRSRTPGDV-SWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSSPLPV 5660

Query: 1273 TALEALLCPSATVTQVCSNPPCETHETGTTN----TATTSNAGSAQRVCSNPPCETHETG 1328
            TA    L  S  VT         T+  GTT+    T++  N  S  +       +T  T 
Sbjct: 5661 TA----LLTSVLVT--------TTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTE 5708

Query: 1329 TTHTAT-TATSNGGTGQPEGGQQPPAGRPCETHQTTST---GTTMSVSVGALLPDATSSH 1384
              H +  T T+    G    G +  +  P ++H + +T   G T ++   ++   +TS+ 
Sbjct: 5709 AMHASMHTNTAVANVGTSISGHESQSSVPADSHTSKATSPMGITFAMGDTSV---STSTP 5765

Query: 1385 RTVESGLEVAAAPSVTP-QAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSN 1443
               E+ ++  +  S+ P    T       T    S    E   T TT  + T     S  
Sbjct: 5766 AFFETRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRT 5825

Query: 1444 QDPPPAASDQGEVESTQGDSVNITSSSAITTTVSST------LTRAVTTVTQSTPVPGPS 1497
                P  S      ST+     IT  S       ST       T  + T++Q+T     S
Sbjct: 5826 TISGPDHSKMSPYISTE----TITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTS 5881

Query: 1498 VPPPEELQVSPGPRQQLPPRQLLQSASTALMGES-------AEVLSASQTPELPAAVDLS 1550
                 E   SP   Q+ P  +   + S +  G S        E  S S    LPA    S
Sbjct: 5882 STASWEGTHSP-VTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHS 5940

Query: 1551 STGEPSSGQESAGSAVVATVVVQ------PPPPTQSEVDQLSLP-------QELMAEAQA 1597
            S     SG     +  V +++            T SE+   SLP       + L +EA  
Sbjct: 5941 SLYSAVSGSSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEAST 6000

Query: 1598 GTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQA---LAIQAVLQAAQQAVMGTGEPMD 1654
             T T+  +  T E    T  +     ++ +  +Q       +      + A++ T  P  
Sbjct: 6001 NTETIHFSENTAETNMGTTNSMHKLHSSVSIHSQPSGHTPPKVTGSMMEDAIVSTSTP-- 6058

Query: 1655 TSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQE-LAALVQQQQLQEAQAQQQHHHLP 1713
             S     V +     L+ E +E     +    T+   + + V      E    +  ++ P
Sbjct: 6059 GSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDP 6118

Query: 1714 TEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATES 1754
            T   A A S   P I     +  + + P T++   + AT++
Sbjct: 6119 TFMPASAQSTKSPDISPEASSSHSNSPPLTISTHKTIATQT 6159



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 156/665 (23%), Positives = 251/665 (37%), Gaps = 82/665 (12%)

Query: 377   TNSLEVSWGAVATADSYLLQLQKYDIP--ATAATATSPTPNPVPSVPANPPKSPAPAAAA 434
             T S+  S GA AT+D   + +   D+P   T+   +S T   + ++P     S  P    
Sbjct: 11376 TPSIATSPGAEATSDFPTITVSP-DVPDMVTSQVTSSGTDTSI-TIPTLTLSSGEPETTT 11433

Query: 435   PAV---QPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP--AVLKV 489
               +   +  T   I  LP +  A    T++ V+ +   S+ + PT   T   P    +++
Sbjct: 11434 SFITYSETHTSSAIPTLPVSPGASKMLTSL-VISSGTDSTTTFPTLTETPYEPETTAIQL 11492

Query: 490   TGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAAL 549
               P A T T +    P     K+    T+LP  +    P  S+  +    SP MS +   
Sbjct: 11493 IHP-AETNTMVPRTTPKFSHSKSD---TTLPVAITSPGPEASSAVSTTTISPDMSDLVTS 11548

Query: 550   AAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPG--TTTLPATVKVAS------SPVM 601
                ++ T     ++ PT+   P       T    P   +TT+  T+   S      +P M
Sbjct: 11549 LVPSSGTDT--STTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNFSHRGSDTAPSM 11606

Query: 602   VSNPA--------TRMLKTAAAQVGTS--VSSATNTSTR-PIITVHKSGTVTVAQQAQVV 650
             V++P         T  +  +   V TS   SSAT+TST  P +T       T A  A   
Sbjct: 11607 VTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTAIPTLTPSPGEPETTASSATHP 11666

Query: 651   TTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG-----P 705
              T  G    T+ +   P S P            M+   T P QTS    + ++      P
Sbjct: 11667 GTQTGF---TVPIRTVPSSEPD----------TMASWVTHPPQTSTPVSRTTSSFSHSSP 11713

Query: 706   VTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGT 765
                 +    P    +   L T + G P  + +   +SGA T  T+    +++ S   P T
Sbjct: 11714 DATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTV---PTLTHSPGMPET 11770

Query: 766   TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGH 825
             T ++ T P +        T  T       P    TT  +T   GA     TA+P   T  
Sbjct: 11771 TALLSTHPRTE-------TSKTFPASTVFPQVSETTASLTIRPGAETS--TALPTQTTSS 11821

Query: 826   G----QQGVTQVVLKGAPGQPGTILRTVPMG---GVRLVTPVTVSAVKPAV---TTLVVK 875
                    G ++V L      PG   +T P+    G    T +  S +   +   T L+  
Sbjct: 11822 LFTLLVTGTSRVDLSPT-ASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLLAT 11880

Query: 876   GTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQ 935
              ++  T+  T+T TVS +++G    S +      +T+  T  + S   + P   + +   
Sbjct: 11881 SSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTVTG 11940

Query: 936   TTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATV- 994
             TT+T       PT       +    T I   + VEA  +     +  +SPT  + T T  
Sbjct: 11941 TTMTLIPS-EMPTPPKTSHGEGVSPTTILRTTMVEATNL----ATTGSSPTVAKTTTTFN 11995

Query: 995   TIADS 999
             T+A S
Sbjct: 11996 TLAGS 12000



 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 261/1285 (20%), Positives = 454/1285 (35%), Gaps = 191/1285 (14%)

Query: 473  SVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSA 532
            S+P+      V + L  + P  T+ +   T+  +  +   PVT       V+     +++
Sbjct: 8551 SLPSVEEASSVSSSL--SSPAMTSTSFFSTLPESISSSPHPVTALLTLGPVKTTDMLRTS 8608

Query: 533  QGTVIGSSPQMSGMAALAAAAAAT----QKIPPSSAPTVLSVPAGTTIVKTMA------- 581
                  S P +S  +A   A +      +KI PSS   V++V  GT I K ++       
Sbjct: 8609 SEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNV--GTVIYKHLSPSSVLAD 8666

Query: 582  --VTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSG 639
               T  T+ +  T  + ++ V  S PA          + T  +S+  +  R I T  ++ 
Sbjct: 8667 LVTTKPTSPMATTSTLGNTSVSTSTPAF------PETMMTQPTSSLTSGLREISTSQETS 8720

Query: 640  TVTV--AQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAV 697
            + T   A  + + T     V++T  L     S PG +   S +   +S      + T   
Sbjct: 8721 SATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQ--STISPEISTETITRISTPLT 8778

Query: 698  TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQAS--GAGTKPTILGISS 755
            T  ++   +T      G    GT     +S    P T    T  S     T P   G   
Sbjct: 8779 TTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSGMTTPMSRGPED 8838

Query: 756  VSPSTTKPGTTTIIKTIPMSAIITQAGATGVT-----------SSP----GIKSPITIIT 800
            VS     P   ++ KT P S++++ +  T  +           SSP     + +P+ + T
Sbjct: 8839 VS----WPSRPSVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSPLRVTSLFTPVMMKT 8894

Query: 801  TKVMTSG-----TGAPAKIITAVPKIATGHGQQGVTQVVLKG--APGQPGTILRTVPMGG 853
            T ++ +      T  P+  IT+   +AT         + L    A  Q GTI        
Sbjct: 8895 TDMLDTSLEPVTTSPPSMNITSDESLATSKATMETEAIQLSENTAVTQMGTISARQEFYS 8954

Query: 854  VRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTL 913
                 P       P VT+  +K     T         S+ +      STS    TP  T 
Sbjct: 8955 SYPGLPEPSKVTSPVVTSSTIKDIVSTTI------PASSEITRIEMESTSTLTPTPRETS 9008

Query: 914  GTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQP 973
                  +SQ I+      +     LT+A    + T  M     P+     T    +  + 
Sbjct: 9009 ------TSQEIHSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSP-DQSTMSQDISTEV 9061

Query: 974  VHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTV 1033
            +  L  S + + +TE    T+T      G    GT+TL          +T TT  + T  
Sbjct: 9062 ITRLSTSPIKTESTEM---TITTQTGSPGATSRGTLTL----------DTSTTFMSGTHS 9108

Query: 1034 VANLG-GHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTAT 1092
             A+ G  H Q T          A  S     V   +   V   S+          T+++ 
Sbjct: 9109 TASQGFSHSQMT----------ALMSRTPGDVPWLSHPSVEEASSASFSLSSPVMTSSSP 9158

Query: 1093 TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVA 1152
             +++     H  S P      +G   T  T +    +  +  +    ++ +  ++ I+  
Sbjct: 9159 VSSTLPDSIHSSSLPVTSLLTSGLVKT--TELLGTSSEPETSSPPNLSSTSAEILAITEV 9216

Query: 1153 TGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLA 1212
            T   E  + +          + S+ +    T    S+  +  P+        +PAF   +
Sbjct: 9217 TTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSSMGITYPTGDTNVLTSTPAFSDTS 9276

Query: 1213 PLSSKVRLS-SPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCE-------SLQGG 1264
             + +K +LS +P + +      + + +  +   SSV  G        E       S+ G 
Sbjct: 9277 RIQTKSKLSLTPGLMETSISEETSSATEKSTVLSSVPTGATTEVSRTEAISSSRTSIPGP 9336

Query: 1265 SPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCET 1324
            + ST  + T++E +   S  +T+  S     T +TG +         ++Q   +     T
Sbjct: 9337 AQSTMSSDTSMETITRISTPLTRKESTDMAITPKTGPSGA-------TSQGTFTLDSSST 9389

Query: 1325 HETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSH 1384
                 TH+ATT         P+     P  R  E     S  + +SV   +  P +  S 
Sbjct: 9390 ASWPGTHSATTQRF------PQSVVTTPMSRGPED---VSWPSPLSVEKNSP-PSSLVSS 9439

Query: 1385 RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
             +V S   + + PS     G++  +P P                     +  TS M    
Sbjct: 9440 SSVTSPSPLYSTPS-----GSSHSSPVPV-------------------TSLFTSIMMKAT 9475

Query: 1445 DPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
            D   A+    E E+T   ++NITS  ++  + ++T T A+     +      +    EEL
Sbjct: 9476 DMLDASL---EPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEEL 9532

Query: 1505 -QVSPG---PRQQLPPRQLLQS-----ASTALMGESA----EVLS-ASQTP---ELPAAV 1547
               SPG   P + + P     S      ST + G S     E+ S +S TP   E   + 
Sbjct: 9533 YSSSPGFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQ 9592

Query: 1548 DLSSTGEPSS---GQESAGSAVVATVVVQP------PPPTQSEVDQLSLPQELMAEAQAG 1598
            D++S+ E S+      S  +  V+   V P      P P QS +  L +  E++      
Sbjct: 9593 DITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTM-SLDISDEVV------ 9645

Query: 1599 TTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEA 1658
             T L  + +  E   +T   +     A ++    L       +   + M  G        
Sbjct: 9646 -TRLSTSPIMTESAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQG-------- 9696

Query: 1659 AATVTQAELGHLSAEGQEGQATTIP 1683
               ++ +E+ +L + G E  + T P
Sbjct: 9697 ---LSHSEMTNLMSRGPESLSWTSP 9718



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 279/1337 (20%), Positives = 476/1337 (35%), Gaps = 213/1337 (15%)

Query: 406  AATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTT------ 459
            A    S T +P     +   ++  PA+A+P+   LT+V   L  Q   +   TT      
Sbjct: 1554 AQDTLSATMSPTHVTQSLKDQTSIPASASPS--HLTEVYPELGTQGRSSSEATTFWKPST 1611

Query: 460  ------------TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPAS 507
                         IQ  P +  ++    ++  T G+  +   T   A T T +   R +S
Sbjct: 1612 DTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSS 1671

Query: 508  -----QAGKAPVTVTSLPAG--------VRMVVPTQSAQGTVI---GSSPQMS--GMAAL 549
                  AG   + VTS P          V  V+   + +G      GSSP+++  G  AL
Sbjct: 1672 TATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTAL 1731

Query: 550  AAA--------AAATQKIPPSSAPTVLSVP-AGTTIVKTMAVTPGTTTLPATVKVASSPV 600
            +++        +  +  IP +S+PT   V   G +   T  VT   T+            
Sbjct: 1732 SSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTS------------ 1779

Query: 601  MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT 660
             +S  + R   ++A  + T++ S  NT    + T   S  +     +  VT  +     +
Sbjct: 1780 DISKSSARTESSSATLMSTALGSTENTGKEKLRTA--SMDLPSPTPSMEVTPWI-----S 1832

Query: 661  ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720
            +TL  +P +     +L  + G     V T    T A     +TG         G   +  
Sbjct: 1833 LTLSNAPNTT---DSLDLSHG-----VHTSSAGTLATDRSLNTGVTRASRLENGSDTSSK 1884

Query: 721  ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI-IT 779
             L +  S     T    +  +S    +P      + +  T+ PG   I  T+P S+I + 
Sbjct: 1885 SLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVE 1944

Query: 780  QAGATGVTSSPGIKS------PITIITTKVMTSGT----GAPAKIITAVPKIATGHGQQG 829
            +  +TG+TS P I S      PIT  T    ++GT      P   +++            
Sbjct: 1945 EVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPY 2004

Query: 830  VTQVVLKGAPGQPGTILR----TVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGT 885
            V  V +  +P    ++      + P     L +  +  + + A+T+ +   TT + T   
Sbjct: 2005 VNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWLWDLTTSLPTTTW 2064

Query: 886  VTGTVSTSLA-GAGGHSTSASLATPITTLGTIATLSSQVINPTAITV----SAAQTTLTA 940
             + ++S +L+ G  G S  +S  T        +T +++  NP   T     +AA T  T 
Sbjct: 2065 PSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTD 2124

Query: 941  AGGLTTPTIT------MQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATV 994
            A  +T  + T         V  P  +T  +  SG+ ++   +  +   +S  T+  T T+
Sbjct: 2125 ASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKL-TRTI 2183

Query: 995  TIADSG-----QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
            ++  S      + +  P TV++   + P       TTNT T+  V + G     T    V
Sbjct: 2184 SLPTSESLVSFRMNKDPWTVSIPLGSHP-------TTNTETSIPVNSAGPPGLSTVASDV 2236

Query: 1050 CDR-QEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPP 1108
             D   + A S+ T +      + V   S+ P +T  T +  T ++ T  +  +   +  P
Sbjct: 2237 IDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKT--THSFRTISSLTHELTSR--VTPIP 2292

Query: 1109 CETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQT 1168
             +   +  +   T A  S+    +R    A    +P V+  S         + S      
Sbjct: 2293 GDWMSSAMSTKPTGASPSITLGERRTITSAAPTTSPIVLTASFT-------ETSTVSLDN 2345

Query: 1169 RQTSATSTTMTVMATGA----PCSAGPLLGPSMAREPGG-RSPAFVQLAPLSSKVRLSSP 1223
              T  TS  +    T        S+  L+  S+A         A +    +S     SSP
Sbjct: 2346 ETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSP 2405

Query: 1224 SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGS-----PSTTVTVTALEAL 1278
            S+        S        T  +  A  P ++    SL GGS     PST    T    +
Sbjct: 2406 SLFS------SDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPV 2459

Query: 1279 LCPSATVTQVCSNPPCETHETG-TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTA- 1336
               SA +     + P  T  T  +T+TA+  N  S+  V ++ P     T    T     
Sbjct: 2460 ETSSALLAW---SRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTTDLPA 2516

Query: 1337 -----TSNGG--------TGQPEGGQQPPAGRPCETHQT-TSTGTTMSVSVGALLPDATS 1382
                 TS  G        T +P     P       T  + TS  + ++ S    +  +  
Sbjct: 2517 MGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSPQ 2576

Query: 1383 SHRTVESGL--EVAAAPS----VTPQAGTALLAPFPTQ-----RVCSNPPCETHETGTTH 1431
            +  T  SG   E +A P     VT  + T L +             S PP +   TGT  
Sbjct: 2577 TPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLS 2636

Query: 1432 ----------------TATTVTSNMSSNQDPPP----AASDQGEVESTQGDSVNITSSSA 1471
                            TAT  TS+++++ D  P    A+   G V  T       ++  A
Sbjct: 2637 GASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSETSNGDA 2696

Query: 1472 ITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQ------------LPP--- 1516
            +     S   R++  +T       P  P          PR              LP    
Sbjct: 2697 LVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGTT 2756

Query: 1517 ------RQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQ-ESAGSAVVAT 1569
                  +    S +TAL+  SA +  AS  P    +  ++S+G   SG   S G+   ++
Sbjct: 2757 GSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSS 2816

Query: 1570 VVVQPPPPTQSEVDQLS 1586
            + +   P   + + +++
Sbjct: 2817 LPLTMNPGEVTAMSEIT 2833



 Score = 78.2 bits (191), Expect = 8e-14
 Identities = 275/1299 (21%), Positives = 463/1299 (35%), Gaps = 215/1299 (16%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGI--TLLPQAAPAPPTTTT 460
            P T+  A   T + +P    +P K+ A   ++   +    +G+  + LP++     T + 
Sbjct: 41   PKTSTGAIVVTEHTLPFT--SPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSE 98

Query: 461  IQVLPTVPGSSISVPTAARTQGVPAVLKVTG---PQATTGTPLVTMRPASQAGKAPVTVT 517
             +  P++       P+    +  PA   V+G   P+  T +        +      V  T
Sbjct: 99   QRTSPSLSPQVNGTPS----RNYPATSMVSGLSSPRTRTSSTEGNFTKEASTYTLTVETT 154

Query: 518  SLPAGVRMVVPTQSAQGTVIGSSPQM------------SGMAALAAAAAATQKIPPSSAP 565
            S P   +  VPT+++  T  G S +             S M   A + A+ +  P S  P
Sbjct: 155  SGPVTEKYTVPTETS--TTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTP 212

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSAT 625
               +V    T  +T    P   TL ++    S     ++     L+   +  G   SS  
Sbjct: 213  AETTVTDSHTPGRT---NPSFGTLYSSFLDLSPKGTPNSRGETSLELILSTTGYPFSSPE 269

Query: 626  NTS---TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS--VPGGSALISNL 680
              S   +R   +   S + +V       T++  G + T     SP+S  VP   A     
Sbjct: 270  PGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLT-----SPLSPGVPEARASTMPN 324

Query: 681  GKVMSVVQTKPVQTSAVTGQASTGPV-TQIIQTKGPLPAGTILKLVTSADGK--PTTIIT 737
              +   +     +TSA   +++   + T  I TK    A TIL     A+    P+T I 
Sbjct: 325  SAIPFSMTLSNAETSAERVRSTISSLGTPSISTKQT--AETILTFHAFAETMDIPSTHIA 382

Query: 738  TTQAS-GAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGV---------T 787
             T AS   G+  T+ G S+ + +TT P TT + +        +     G          T
Sbjct: 383  KTLASEWLGSPGTLGGTSTSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLET 442

Query: 788  SSPGIKSPI--TIITT---KVMTSGTGAPAKIITAVP---------------KIATGHGQ 827
            S+PG +S +  T++ T     + S   +P+++ ++ P                    HG 
Sbjct: 443  SAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGS 502

Query: 828  QGVTQVVLKGAP--------------GQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLV 873
              + +                      +P           ++   P   ++V   +TT V
Sbjct: 503  SDILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSV 562

Query: 874  VKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSA 933
                +G TTL T      +S  G     TSA      +T G     + Q   PT I+++ 
Sbjct: 563  PSVVSGFTTLKT------SSTKGIWLEETSADTLIGESTAG---PTTHQFAVPTGISMTG 613

Query: 934  AQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTAT 993
              +T  + G  TT  +T    S  T   L  A +GV        PVS+  SP   +  A 
Sbjct: 614  GSSTRGSQG--TTHLLTRATASSETSADLTLATNGV--------PVSV--SPAVSKTAA- 660

Query: 994  VTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQ 1053
                 S  G  +P + T+V S  P    ET +  ++      +LG  P  T+  F     
Sbjct: 661  ---GSSPPGGTKP-SYTMVSSVIP----ETSSLQSSAFREGTSLGLTPLNTRHPFSSPEP 712

Query: 1054 EAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHE 1113
            ++A     ST      S+  + S                +ATS  +     S+    T E
Sbjct: 713  DSAGHTKIST------SIPLLSS--------ASVLEDKVSATSTFSHHKATSSITTGTPE 758

Query: 1114 TGT-TNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTS 1172
              T T  ++  +SS+  ++        AA +P   R+  AT  L     S  +       
Sbjct: 759  ISTKTKPSSAVLSSMTLSN--------AATSPE--RVRNATSPLTHPSPSGEE------- 801

Query: 1173 ATSTTMTVMATGAPCSAGPLLGPS-MAREPGGRSPAFVQLAPLS---SKVRLSSPSIKDL 1228
             T+ ++  ++T A  +  P + P+         SP+ + L  +S   +    S+PS    
Sbjct: 802  -TAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLF 860

Query: 1229 PAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQV 1288
             +G  +   S  ++++        R      S+      T  T     A    S  V+++
Sbjct: 861  TSGEETEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSEL 920

Query: 1289 CSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATT-------ATSNGG 1341
                        T++T+ T++ GSA       P  +H TGT   + T       + +   
Sbjct: 921  ----------RATSSTSVTNSTGSAL------PKISHLTGTATMSQTNRDTFNDSAAPQS 964

Query: 1342 TGQPEGGQQPPAGRPCETHQTTSTGTTMS--VSVGALLPDATSSHR--------TVESGL 1391
            T  PE   +   G P  T   +++ T++S  V V      ATSS          T     
Sbjct: 965  TTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTT 1024

Query: 1392 EVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH-ETGTTHTATT----------VTSNM 1440
            E    P     A T +  P     +       +H   GTT ++ T          V+ ++
Sbjct: 1025 ETTNGPGSMAVASTNI--PIGKGYITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSV 1082

Query: 1441 SSNQDPPPAASD----QGEVESTQGDSVNITSSSAITTT---VSSTLTRAVTTVTQSTPV 1493
            S +Q    A S       +   T  D V   +S  IT      SS LT  +T     +P 
Sbjct: 1083 SPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTATHPPSPD 1142

Query: 1494 PGPS----VPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDL 1549
            PG +    +        SP P+  +      Q  +T+++ ++ E  S    P LP+   L
Sbjct: 1143 PGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVET-SRWNMPNLPSTTSL 1201

Query: 1550 SSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLP 1588
            + +  P+SG     + V       P P T  E  +  LP
Sbjct: 1202 TPSNIPTSGAIGKSTLVPLDT---PSPATSLEASEGGLP 1237



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 322/1623 (19%), Positives = 560/1623 (34%), Gaps = 335/1623 (20%)

Query: 435  PAVQPLTQVGITLLPQA--APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP 492
            P V+  + V   +   A  +P+P ++T+ Q +P+ P    ++PT+        VL  T P
Sbjct: 5327 PPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTD-VLGTTSP 5385

Query: 493  QATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAA 552
            ++ T +P      +S   + P T          +  + +   T +G+S       +   A
Sbjct: 5386 ESVTSSP---PNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVGTSGSGHKSQSSVLA 5442

Query: 553  AAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKT 612
             + T K  P  + T       +T+  T +V+  T  +  T ++ + P    +P  R    
Sbjct: 5443 DSETSKATPLMSTT-------STLGDT-SVSTSTPNISQTNQIQTEPTASLSPRLR---- 5490

Query: 613  AAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPG 672
               +  TS  +++ T T    +   +G +T A + ++ ++     T    L +  I+   
Sbjct: 5491 ---ESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSR----TSISDLDRPTIAPDI 5543

Query: 673  GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLV------T 726
             + +I+ L        T P+ T +     +T   T    ++G LP  T   L       T
Sbjct: 5544 STGMITRLF-------TSPIMTKSAEMTVTTQTTTPGATSQGILPWDTSTTLFQGGTHST 5596

Query: 727  SADGKPTTIITTTQASGAG---------TKPTILGISSVSPSTTKPG--TTTIIKTIPMS 775
             + G P + ITT ++   G          + T  G S +SPS T P   ++T  ++IP S
Sbjct: 5597 VSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTSPESIPSS 5656

Query: 776  ----------AIITQAGATGVTSS-------PGIKSP----ITIITTKVMTSGTGAPAKI 814
                       ++T     G TS        P + SP    +T       T    A    
Sbjct: 5657 PLPVTALLTSVLVTTTNVLGTTSPEPVTSSPPNLSSPTQERLTTYKDTAHTEAMHASMHT 5716

Query: 815  ITAVPKIAT---GHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAV-- 869
             TAV  + T   GH  Q          P    T   T PMG    +   +VS   PA   
Sbjct: 5717 NTAVANVGTSISGHESQS-------SVPADSHTSKATSPMGITFAMGDTSVSTSTPAFFE 5769

Query: 870  -------TTLVVKGTTGVTT---LGTVTGTVS-----------------------TSLAG 896
                   T+ ++ G     T   + TVT T +                       T+++G
Sbjct: 5770 TRIQTESTSSLIPGLRDTRTSEEINTVTETSTVLSEVPTTTTTEVSRTEVITSSRTTISG 5829

Query: 897  AGGHSTSASLATP-ITTLGTIATLSSQ----VINPTAITVSAAQTTLT-------AAGGL 944
                  S  ++T  IT L T   ++      + N T    + +Q TLT       +  G 
Sbjct: 5830 PDHSKMSPYISTETITRLSTFPFVTGSTEMAITNQTGPIGTISQATLTLDTSSTASWEGT 5889

Query: 945  TTPTITMQPVSQPTQVTLITAPSGVEAQ----------PVHDLPVSIL------------ 982
             +P     P S+ T  T+  +  GV  Q          P   +P+  +            
Sbjct: 5890 HSPVTQRFPHSEET-TTMSRSTKGVSWQSPPSVEETSSPSSPVPLPAITSHSSLYSAVSG 5948

Query: 983  ASPTTEQP-TATVTIADSGQGDVQPGTVTLVCSNPPCETHETG---TTNTATTTVVANLG 1038
            +SPT+  P T+ +T       D+      LV S+ P  +  +G   T+  +T T   +  
Sbjct: 5949 SSPTSALPVTSLLTSGRRKTIDMLDTHSELVTSSLPSASSFSGEILTSEASTNTETIHFS 6008

Query: 1039 GHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNM 1098
             +   T +       +  +S+  S   Q +G      +    E     T+   +  T N+
Sbjct: 6009 ENTAETNMGTTNSMHKLHSSV--SIHSQPSGHTPPKVTGSMMEDAIVSTSTPGSPETKNV 6066

Query: 1099 AGQHGCSNPPCETHETGT------TNTATTAMSSVGANHQRDARRA-CAAGTPAVIRISV 1151
                     P E  E  T      T  + T  SSV  +   +  RA      P  +  S 
Sbjct: 6067 DRDSTSPLTP-ELKEDSTALVMNSTTESNTVFSSVSLDAATEVSRAEVTYYDPTFMPASA 6125

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGP---------SMAREPG 1202
             +          S   +     T +T   +AT    S    LG          + A  P 
Sbjct: 6126 QSTKSPDISPEASSSHSNSPPLTISTHKTIATQTGPSGVTSLGQLTLDTSTIATSAGTPS 6185

Query: 1203 GRSPAFVQLAPLSSKVRLSSPSIKDLP-AGRHSHAVSTAAMTRSSVGAGEPRMAPVCESL 1261
             R+  FV     S      +  +K  P +   ++++S+ A    +        +PV  +L
Sbjct: 6186 ARTQDFVDSETTSVMNNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSP-----SPVTSTL 6240

Query: 1262 QGGSPSTTVTVTALE----ALLCPSATVTQVCSNPPCETHETGTTNTATTS--------N 1309
            Q  S S+ V+VT++     A +    T  +  +  P     T  T+ ATT         N
Sbjct: 6241 QEHSTSSLVSVTSVPTPTLAKITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTMHPSIN 6300

Query: 1310 AGSAQRVCSNPPCETHET------------GTTHTATTATSNGGTGQPEGGQQPPAG--- 1354
               A    ++ P E + T                T+T+  S   T  P            
Sbjct: 6301 TAVANVGTTSSPNEFYFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESET 6360

Query: 1355 --------RPCETHQ----TTSTGTTMSVSVGALLPDA-----TSSHRTVESGLEVAAAP 1397
                    R   T Q    ++ T T    +  A   +      TSS RT   G E    P
Sbjct: 6361 TFSLIFRLRETSTSQKIGSSSDTSTVFDKAFTAATTEVSRTELTSSSRTSIQGTE---KP 6417

Query: 1398 SVTPQAGTALLAPFPT--------QRVCSNP--PCETHETGTTHTATTVTSNMSSNQDPP 1447
            +++P   T  +    T        +R  +    P      GT    T++T++ +      
Sbjct: 6418 TMSPDTSTRSVTMLSTFAGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAM 6477

Query: 1448 P---AASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEEL 1504
                +  D   + S   + ++ TS  ++  T SS+   ++  +T  +PVP      PE  
Sbjct: 6478 THGFSQLDLSTLTSRVPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVP---TTLPESR 6534

Query: 1505 QVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAA---------------VDL 1549
              SP     LP   L+++        S      S + ++P                 + +
Sbjct: 6535 PSSPVHLTSLPTSGLVKTTDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAV 6594

Query: 1550 SSTGEPSSGQESAGSAV-----------------VATVVVQPPPPTQSEVDQLSLPQEL- 1591
            ++ G  +S +ES  S                   +   +V    P  SE+ ++ +     
Sbjct: 6595 TNVGTTTSEKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPGSSEITRIEMESTFS 6654

Query: 1592 MAEAQAGTTTLMVTGLTPEELAV-----TAAAEAAAQAAA-------------------- 1626
            +A    GT+T     ++ E+ AV     T A E +    A                    
Sbjct: 6655 LAHGLKGTSTSQDPIVSTEKSAVLHKLTTGATETSRTEVASSRRTSIPGPDHSTESPDIS 6714

Query: 1627 TEEAQALAIQ-AVLQAAQQAVMG-TGEPM-DTSEAAATV----TQAELGHLSAEGQEGQA 1679
            TE   +L I   + +++   ++  TG P+  TS+   T+    T +  G  S   QE   
Sbjct: 6715 TEVIPSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPH 6774

Query: 1680 TTIPIVLTQQ-ELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAG 1738
            + +  V+ +  E+ +      +++           + +L P+ ++  P + S        
Sbjct: 6775 SEMTTVMNKDPEILSWTIPPSIEKTSF--------SSSLMPSPAMTSPPVSS-------- 6818

Query: 1739 TVPSTVALLPSTATESLAPSNTF------VAPQPVVVASPAKLQAAA----TLTEVANGI 1788
            T+P T+   PS  T  L PS          +P+P   +SP  L + +    T  E    I
Sbjct: 6819 TLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEP-TTSSPPNLSSTSHEILTTDEDTTAI 6877

Query: 1789 ESL 1791
            E++
Sbjct: 6878 EAM 6880



 Score = 75.5 bits (184), Expect = 5e-13
 Identities = 340/1628 (20%), Positives = 552/1628 (33%), Gaps = 261/1628 (16%)

Query: 395  LQLQKYDIPATAATATSPTPNPVPSVPAN-----------PPKSPAPAAAAPAVQPL--- 440
            +Q     +P   +T+ +P+      VP +            P +P       ++  L   
Sbjct: 3680 VQRMSISVPDILSTSWTPSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWD 3739

Query: 441  TQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPL 500
            T   ++       AP   TT Q L     + IS  T+     +  +     P A   +  
Sbjct: 3740 TGRSLSSATATTSAPQGATTPQELTLE--TMISPATSQLPFSIGHITSAVTPAAMARSSG 3797

Query: 501  VTM-RPASQAGKAPVTVTSLPAGVRM---VVPTQSAQGTVIGSSP----------QMSGM 546
            VT  RP   + KA  T T LP         VP  +A  T +   P          Q  G 
Sbjct: 3798 VTFSRPDPTSKKAEQTSTQLPTTTSAHPGQVPRSAA--TTLDVIPHTAKTPDATFQRQGQ 3855

Query: 547  AALAAAAAAT-------QKIPPS-----------SAPTVLSVPAGTTIVKTMAVTPGTTT 588
             AL   A AT       +K  PS           S  T+  V + +++++T+     T  
Sbjct: 3856 TALTTEARATSDSWNEKEKSTPSAPWITEMMNSVSEDTIKEVTSSSSVLRTL----NTLD 3911

Query: 589  LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT-STRPIITV--HKSGTVTVAQ 645
            +       SSP   S+P  R+  + +     ++  +TNT  T   +T   H S +   A 
Sbjct: 3912 INLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTIPAH 3971

Query: 646  QAQ------VVTT-----VVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPV-Q 693
             A       VVTT      +  ++ T     +       S L   L  V   + T    Q
Sbjct: 3972 SASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQ 4031

Query: 694  TSAVTGQAST----GPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPT 749
            TS ++   ST    GP T+I  +K  + +  + + + S+D  P+  IT      A T+  
Sbjct: 4032 TSIISSPGSTAITKGPRTEITSSKR-ISSSFLAQSMRSSDS-PSEAITRLSNFPAMTES- 4088

Query: 750  ILGISSVSPSTTKPGTTTI-IKTIPMSAIITQAGATGVTSSPGIKSPITIITTK------ 802
              G   ++  T+ PG T++   T+  SA  +  G    T+     S  T + +K      
Sbjct: 4089 --GGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSEKTTLFSKGPEDTS 4146

Query: 803  ---------VMTSGTGAPAKIITAVPKI---ATGHGQQG---VTQVVLKGAPGQPGTILR 847
                       +S +  P    T+   I   + GH       VT V L    G    + +
Sbjct: 4147 QPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFLSETSG----LGK 4202

Query: 848  TVPMGGVRL-----VTPVTVSAVKPAVTTLVVKGTT-----GVTTLGTVTGTVSTSLAGA 897
            T  M  + L     + P   S    A++T      T        T  T     S+  +  
Sbjct: 4203 TTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPI 4262

Query: 898  GGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQP 957
             GH+  +   +P+ T   +  ++S      +   +  +T  +   GL   + +    S  
Sbjct: 4263 PGHTKPSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSAT 4322

Query: 958  TQVTLIT-APSGVEAQPVHDLPVSILASPTTEQP----TATVTIADSGQGDVQPGTVTLV 1012
               T+IT   SG     V     +  +  +   P    T+T T  D       P T  ++
Sbjct: 4323 ETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVS---TNPSTSLIM 4379

Query: 1013 C-SNPPCETHETGTTNTAT-------TTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTV 1064
              S+    T +TG T  AT       T+ +  L   P      F+   +    S     V
Sbjct: 4380 TESSGVTITTQTGPTGAATQGPYLLDTSTMPYLTETPLAVTPDFMQSEKTTLISKGPKDV 4439

Query: 1065 GQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAM 1124
               +   V   S P   T    TT     ATS + GQH  S+P   T    +    TT M
Sbjct: 4440 SWTSPPSVAETSYPSSLTPFLVTT--IPPATSTLQGQH-TSSPVSATSVLTSGLVKTTDM 4496

Query: 1125 SSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATG 1184
             +       ++ +     +  ++    AT  +E    S ++  T   +A+S    V+ + 
Sbjct: 4497 LNTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAH--VLHST 4554

Query: 1185 APCSAGPLLGPSMAREPGGRSPAFVQLA-PLSSKVRLSSPSIKDLPAGRHSHAV--STAA 1241
             P S+ P    S          A   ++ P S    +       L AGR  ++      +
Sbjct: 4555 LPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKENSTLQEMNS 4614

Query: 1242 MTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCS----NPPCETH 1297
             T S++      +  + E+ +   PS   T     A       +  V S    N P  T 
Sbjct: 4615 TTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFSVASSRLSNSPPMTI 4674

Query: 1298 ETGTTNTATTSNAGSAQRVCSNPPCETHET----------GTTHTATTATSNGGT---GQ 1344
             T  T T T S+ G+  ++       T ET          G  H+  T   N       Q
Sbjct: 4675 STHMTTTQTGSS-GATSKIPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQ 4733

Query: 1345 PEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPD--ATSSHRTVESGLE---VAAAPSV 1399
                 Q  A  P  + Q     TT+  SV A  P   +TSS  ++ S L    V  A  V
Sbjct: 4734 TNPPFQDEASSP--SSQAPVLVTTLPSSV-AFTPQWHSTSSPVSMSSVLTSSLVKTAGKV 4790

Query: 1400 TPQAGTALLAPFPTQRVCSN---PPCETHETGTTHTA-TTVTSNMSSNQDPPPAASDQGE 1455
                 T   +P        +       T +  TTH +  TV +N+ +      + S    
Sbjct: 4791 DTSLETVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSA 4850

Query: 1456 V-ESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVS------- 1507
              E ++  S N+T+S+   TT+S ++ ++  T    T       P   E  +S       
Sbjct: 4851 YPEPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSST 4910

Query: 1508 ------------------------------PGPRQQLPPRQLLQSASTAL-----MGESA 1532
                                          PGP Q      +    +T L     M ESA
Sbjct: 4911 ETSTVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDISTETNTRLSTSPIMTESA 4970

Query: 1533 EVLSASQTPELPAAVDLSSTGEPSSGQESAG---------SAVVATVVVQPPPPTQS--- 1580
            E+   +QT    A    + T +PS+    AG         S +  T ++   P   S   
Sbjct: 4971 EITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQLDVTTLMSRIPQDVSWTS 5030

Query: 1581 --EVDQLSLPQELMAEAQAGTTTLMVTGLTPEELA------VTAAAEAAAQAAATEEAQA 1632
               VD+ S P   ++     T +L+ + L  ++L+      +T+          T     
Sbjct: 5031 PPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPV 5090

Query: 1633 LAIQAVLQAAQQAVMGTG-EPMDTSEAAATVTQAEL-------GHLS-----AEGQEGQA 1679
             +      +    ++ T  +  DT E   ++   E        GH S     A+ +  +A
Sbjct: 5091 TSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNSGHESHSPALADSETPKA 5150

Query: 1680 TTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNE---L 1736
            TT  ++ T     A      +  +         PT  L P       + ES+   +   L
Sbjct: 5151 TTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPTDTSFL 5210

Query: 1737 AGTVPS-TVALLPSTAT------------ESLAPSNTFVAPQPVVVASPAKLQAA-ATLT 1782
               VP+ T+  + ST              +S  P +TF    P V  S  K ++A  T+T
Sbjct: 5211 LSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVFTSSIKTKSAEMTIT 5270

Query: 1783 EVANGIES 1790
              A+  ES
Sbjct: 5271 TQASPPES 5278



 Score = 75.1 bits (183), Expect = 7e-13
 Identities = 300/1534 (19%), Positives = 517/1534 (33%), Gaps = 301/1534 (19%)

Query: 404  ATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQV 463
            ++A++ TSP+   + ++ AN   S   +  AP    L+Q        ++PA  +   +  
Sbjct: 3483 SSASSVTSPSIG-LETLRANV--SAVKSDIAPTAGHLSQT-------SSPAEVSILDVTT 3532

Query: 464  LPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQ----AGKAPVTVTSL 519
             PT PG S ++ T          +  T P    G   +   PA++    + + P T +S 
Sbjct: 3533 APT-PGISTTITTMGTNS-----ISTTTPNPEVGMSTMDSTPATERRTTSTEHPSTWSST 3586

Query: 520  PAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQ---KIPPSSAPTVLSVPAGTTI 576
             A     V   ++   V  S   +S M   +  A++T+      P    TV+     T  
Sbjct: 3587 AASDSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTPS 3646

Query: 577  VKTMAVTPGTTTLPATVK----VASSPVMVSNPATRML--------------KTAAAQVG 618
                AV   T+T   T+      AS+P+   +   RM                T A  V 
Sbjct: 3647 SDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAEDVP 3706

Query: 619  TSVSSATNTSTR-----PIITVHKSGTVTV-------AQQAQVVTTVVGGVTKTITLVKS 666
             S+ S  + ST+     P+ T       T+          A   T+   G T    L   
Sbjct: 3707 VSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELTLE 3766

Query: 667  PISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVT 726
             +  P  S L  ++G + S V    +  S+    +   P ++                  
Sbjct: 3767 TMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSK------------------ 3808

Query: 727  SADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGV 786
             A+   T + TTT A       +      V P T K    T  +    +A+ T+A AT  
Sbjct: 3809 KAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQ-GQTALTTEARATSD 3867

Query: 787  TSSPGIKS-PITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTI 845
            + +   KS P     T++M S +    K +T+                          ++
Sbjct: 3868 SWNEKEKSTPSAPWITEMMNSVSEDTIKEVTS------------------------SSSV 3903

Query: 846  LRTVPMGGVRLVTPVTVSA---------VKPAVTTL----VVKGTTGVTTLGTVTGTVST 892
            LRT+    + L +  T S          + P+ +T     +   T  V T G VT +   
Sbjct: 3904 LRTLNTLDINLESGTTSSPSWKSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHA 3963

Query: 893  SLAGAGGHSTSASLATPITTLGT-------------------------IATLSSQVINPT 927
            S +    HS S+ L +P+ T  T                           T+  + ++P 
Sbjct: 3964 SHSTIPAHSASSKLTSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSPY 4023

Query: 928  AITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTT 987
              T S  QT++ ++ G T   IT  P ++ T    I++    ++    D P     S   
Sbjct: 4024 MDTSSTTQTSIISSPGST--AITKGPRTEITSSKRISSSFLAQSMRSSDSP-----SEAI 4076

Query: 988  EQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQ 1047
             + +    + +SG      G +  + ++PP  T  + +  T  T+  A+  G P  T  +
Sbjct: 4077 TRLSNFPAMTESG------GMILAMQTSPPGAT--SLSAPTLDTSATASWTGTPLATTQR 4128

Query: 1048 FVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNT-----ATTATSNM---- 1098
            F    +    S       Q +          P    ET ++++     ATT+ SN+    
Sbjct: 4129 FTYSEKTTLFSKGPEDTSQPS----------PPSVEETSSSSSLVPIHATTSPSNILLTS 4178

Query: 1099 AGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEA 1158
             G    S PP        T+   +  S +G      +R +   GT     +S   G   +
Sbjct: 4179 QGHSPSSTPP-------VTSVFLSETSGLGKTTDM-SRISLEPGTSLPPNLSSTAGEALS 4230

Query: 1159 AQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKV 1218
               +    +    SA +    + AT +  S  P+        PG   P+           
Sbjct: 4231 TYEASRDTKAIHHSADTAVTNMEATSSEYS--PI--------PGHTKPS----------- 4269

Query: 1219 RLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL 1278
            + +SP +        SH +     + S  G+ E        S+  G    + +  A  A 
Sbjct: 4270 KATSPLVT-------SHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSA- 4321

Query: 1279 LCPSATVTQVCSNPPCETHETGT--TNTATTSNAGSAQRVCSNPPCETHETGTTHTATTA 1336
               ++TV    S+    TH T T  T ++ TS +   Q + S        T  + +    
Sbjct: 4322 -TETSTVITHVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTSLIMT 4380

Query: 1337 TSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAA 1396
             S+G T                   TT TG T + + G  L D ++     E+ L  A  
Sbjct: 4381 ESSGVT------------------ITTQTGPTGAATQGPYLLDTSTMPYLTETPL--AVT 4420

Query: 1397 PSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEV 1456
            P       T L++  P     ++PP     +  +     + + +     PP  ++ QG+ 
Sbjct: 4421 PDFMQSEKTTLISKGPKDVSWTSPPSVAETSYPSSLTPFLVTTI-----PPATSTLQGQH 4475

Query: 1457 ESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPP 1516
             S+   + ++ +S  + TT    L  ++  VT S   P     P  E+  +      +  
Sbjct: 4476 TSSPVSATSVLTSGLVKTT--DMLNTSMEPVTNS---PQNLNNPSNEILATLAATTDIET 4530

Query: 1517 RQLLQSASTALMG--ESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQP 1574
                 + +   MG   SA VL ++    LP + + S+   P     S G A+ +  +   
Sbjct: 4531 IHPSINKAVTNMGTASSAHVLHST----LPVSSEPSTATSPMVPASSMGDALASISI--- 4583

Query: 1575 PPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATE------ 1628
              P     D    P   +   +   +TL     T E   + +     A   AT+      
Sbjct: 4584 --PGSETTDIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSF 4641

Query: 1629 -------EAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATT 1681
                    AQ+     +   A   +  +  P  T     T TQ         G  G  + 
Sbjct: 4642 DATFIPTPAQSTKFPDIFSVASSRL--SNSPPMTISTHMTTTQT--------GSSGATSK 4691

Query: 1682 IPIVLTQQEL-AALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDP-----AIESNCLNE 1735
            IP+ L    L  +      + E  A  +        +      N P     +  S+    
Sbjct: 4692 IPLALDTSTLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQDEASSPSSQAPV 4751

Query: 1736 LAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKP 1795
            L  T+PS+VA  P   + S           PV ++S        T  +V   +E++    
Sbjct: 4752 LVTTLPSSVAFTPQWHSTS----------SPVSMSSVLTSSLVKTAGKVDTSLETV---- 4797

Query: 1796 DLPPPPSKAPMKKENQWFDVGVIKG--TNVMVTH 1827
                  + +P    N   D+ V     T++  TH
Sbjct: 4798 ------TSSPQSMSNTLDDISVTSAATTDIETTH 4825



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 274/1349 (20%), Positives = 468/1349 (34%), Gaps = 198/1349 (14%)

Query: 559  IPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASS---PVMVSNPATRMLKTAAA 615
            +P +++ T  ++P    I K+  V P  T  PAT   AS    P + + P +    T + 
Sbjct: 1195 LPSTTSLTPSNIPTSGAIGKSTLV-PLDTPSPATSLEASEGGLPTLSTYPEST--NTPSI 1251

Query: 616  QVGTSVSSATNTSTR-PIITVHKSGTVTVAQQAQVVTTV-VGGVTKTITLVKSP-ISVPG 672
             +G   SS + ++ +  + +V K G+ T      + T + V       +   SP ++ PG
Sbjct: 1252 HLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPG 1311

Query: 673  GSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP 732
             +   S       +  T P  TS+   Q ST    + ++T                +  P
Sbjct: 1312 ETNTGSTWDPTTYITTTDPKDTSSA--QVSTPHSVRTLRT---------------TENHP 1354

Query: 733  TTIITTTQASGAGTKPTILGISSVSPSTTKPGTT--TIIKTIPMSA------IITQAGAT 784
             T   T  A     K     ISS SP+ T P T   TI  T   S       +  ++   
Sbjct: 1355 KTESATPAAYSGSPK-----ISS-SPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGF 1408

Query: 785  GVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGT 844
               S+PG  S + I T+  + S T      +   P +     Q  +T  +          
Sbjct: 1409 ETQSAPGPVS-VVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTE 1467

Query: 845  ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSL---AGAGGHS 901
             + +  +      +P++  A+ P ++T   + +        +  T ST+L    G     
Sbjct: 1468 EMASTDLDISSPSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLG 1527

Query: 902  TSASLAT-PITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960
             +  L T PIT L T  T +S + + T      AQ TL+A     +PT   Q +   T +
Sbjct: 1528 RTGDLTTVPITPLTT--TWTSVIEHSTQ-----AQDTLSAT---MSPTHVTQSLKDQTSI 1577

Query: 961  TLITAPSGV-EAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCE 1019
                +PS + E  P     +      ++E  T      D+   +++ G  T + S PP +
Sbjct: 1578 PASASPSHLTEVYP----ELGTQGRSSSEATTFWKPSTDTLSREIETGP-TNIQSTPPMD 1632

Query: 1020 THETGTTNTATTTVVANL---GGHPQPTQVQFVCDRQEAAAS---------LVTSTVGQQ 1067
               TG++++  T  +A+L      P  T      +R+ + A+         LVTS  G+ 
Sbjct: 1633 NTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRS 1692

Query: 1068 NGSVVRVCSNPPCETHETGTTNTA--TTATSNMAGQHGCSNPPCETHETGTTNTATTAMS 1125
                +   S+   E+   G T+++  ++   N  G    S+    ++  G+  + +  ++
Sbjct: 1693 ISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLT 1752

Query: 1126 SVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGA 1185
            S       +        T  V  +  +  +  +A+   S      T+  ST  T      
Sbjct: 1753 SSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLR 1812

Query: 1186 PCSAG-PLLGPSMAREPG-----GRSPAFVQLAPLSSKVRLSS----------------- 1222
              S   P   PSM   P        +P       LS  V  SS                 
Sbjct: 1813 TASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAGTLATDRSLNTGVTRA 1872

Query: 1223 --------PSIKDLPAGRHSHAVST---AAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
                     S K L  G  +H   T    +   SS+       AP  E+    +P     
Sbjct: 1873 SRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAI 1932

Query: 1272 VTALEALLCPSATV--TQVCSNPPCE----THETGT------TNTATTSNAGSAQRVCSN 1319
               L     P   V  T + S P       TH   T      T+T T   +       S+
Sbjct: 1933 SLTLPFSSIPVEEVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSS 1992

Query: 1320 PPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMS--------- 1370
                     T +  + A S   T +           P  +    S  +T+S         
Sbjct: 1993 EKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASLESLDSTISRRNAITSWL 2052

Query: 1371 ----VSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHE 1426
                 S+      +TS    + SG    + PS T        A   +     NP  ETH 
Sbjct: 2053 WDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHG 2112

Query: 1427 TGTTHTAT--TVTSNMSSNQDPPPAASDQGEVE-----STQGDSVNITSSSAITTTVSST 1479
               T  +T  T  S+++   + P  AS   EV      +++ D   +TS S    ++  T
Sbjct: 2113 PQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSL-GT 2171

Query: 1480 LTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQ 1539
             + A T +T++      S+P  E L      +        L S  T     S  V SA  
Sbjct: 2172 ASSAGTKLTRTI-----SLPTSESLVSFRMNKDPWTVSIPLGSHPTTNTETSIPVNSAGP 2226

Query: 1540 TPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGT 1599
                  A D+  T  PS G ES     + TV   P P T+                    
Sbjct: 2227 PGLSTVASDVIDT--PSDGAES-----IPTVSFSPSPDTE-------------------- 2259

Query: 1600 TTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTG-EPMDTSEA 1658
                VT ++      T +    +       ++   I     ++  +   TG  P  T   
Sbjct: 2260 ----VTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPTGASPSITLGE 2315

Query: 1659 AATVTQAELGHLSAEGQEGQATTIPIVL----TQQELAALVQQQQLQEAQA--QQQHHHL 1712
              T+T A              TT PIVL    T+    +L  +  ++ +     ++ + L
Sbjct: 2316 RRTITSA------------APTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNEL 2363

Query: 1713 PTEALAPADSLNDPAIESNC-LNELAGTVPSTVALLPSTATESLAPSNTFVAPQPVVVAS 1771
            P+++ + +D +N     S   + + A   P++++ + ++++ SL  S+    P      +
Sbjct: 2364 PSDSSSSSDLINTSIASSTMDVTKTASISPTSISGMTASSSPSLFSSDRPQVPTSTTETN 2423

Query: 1772 PAKLQAAATLTEVANGIESLGVKPDLPPP 1800
             A   + ++ T   +G  ++G  P   PP
Sbjct: 2424 TATSPSVSSNTYSLDGGSNVGGTPSTLPP 2452



 Score = 68.9 bits (167), Expect = 5e-11
 Identities = 300/1441 (20%), Positives = 485/1441 (33%), Gaps = 236/1441 (16%)

Query: 402  IPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTT--- 458
            IP    +A S    PV S  ++P K+ A    AP    + Q  +T      P+  T    
Sbjct: 2848 IPVKPTSAESGLLTPV-SASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSAS 2906

Query: 459  --TTIQVLPTVPGSSISVPTA-----------ARTQGVPAVLKVTGPQAT--TGTPLVTM 503
              T  Q L T+P S  S  ++           AR       +  +  Q+T  T TP  + 
Sbjct: 2907 LPTPGQSLNTIPDSDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSA 2966

Query: 504  RPASQAGKAPVTVTSLPAGVR-----MVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQK 558
             P S AG  P   TS     R     M  P  S   + + S+   S +  L +   A + 
Sbjct: 2967 SP-SMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARS 3025

Query: 559  IPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLK------- 611
               SS+P  LS    T+ +   A T   T+L     +A  P ++ +  T  L        
Sbjct: 3026 -GSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTL 3084

Query: 612  ----------------------TAAAQVGTSVSSATNTSTRPIITVHK------------ 637
                                  TA  Q  T   S T TS  P+ +  +            
Sbjct: 3085 NMSQEEPPELTSSQTIAEEEGTTAETQTLTFTPSETPTSLLPVSSPTEPTARRKSSPETW 3144

Query: 638  SGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAV 697
            + +++V  +  +V T  G +  TI +  S  +  G S   +   +  S     P  TS  
Sbjct: 3145 ASSISVPAKTSLVETTDGTLVTTIKM--SSQAAQGNSTWPAPAEETGS----SPAGTSPG 3198

Query: 698  TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKP--TTIITTTQASGAGTKPTILGISS 755
            + + ST    +I+ +K P  +  I   V ++  K   TT+   T       + T LG  S
Sbjct: 3199 SPEMST--TLKIMSSKEPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGS 3256

Query: 756  VSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKV-----MTSGTGA 810
             S S    GTT+  K+   + + T+     V+ SP      T + +        +  T +
Sbjct: 3257 TSISHLPTGTTSPTKSPTENMLATER----VSLSPSPPEAWTNLYSGTPGGTRQSLATMS 3312

Query: 811  PAKIITAVPKIATGHGQQGVTQVVLK-----------GAPGQPGTILRTVPMGGVRLVTP 859
               + +   +  TG GQQ   ++V K              G  G    ++      L  P
Sbjct: 3313 SVSLESPTARSITGTGQQSSPELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDP 3372

Query: 860  VTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPIT-------- 911
            VT      ++T      T    +   +  TV  +   A    TS S+    +        
Sbjct: 3373 VTSPNSVSSLTDKSKHKTETWVSTTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQ 3432

Query: 912  TLGTIATL--SSQVINPTAITVSAAQTTLTA--AGGLTTPTITMQPVSQPTQVTLITAPS 967
            T G+  TL  S  V N   IT +A  T+L +  +G     ++T     + +  + +T+PS
Sbjct: 3433 TSGSDITLGASPDVTNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPS 3492

Query: 968  -GVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTT 1026
             G+E      L  ++ A  +   PTA      S   +V    VT   +     T  T  T
Sbjct: 3493 IGLET-----LRANVSAVKSDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGT 3547

Query: 1027 NTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG 1086
            N+ +TT        P P       D   A     TST               P     T 
Sbjct: 3548 NSISTTT-------PNPEVGMSTMDSTPATERRTTST-------------EHPSTWSSTA 3587

Query: 1087 TTN--TATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTP 1144
             ++  T T  TSN+  +   S     T  T +   ++T + S+   H R      +  TP
Sbjct: 3588 ASDSWTVTDMTSNL--KVARSPGTISTMHTTSFLASSTELDSMSTPHGRITVIGTSLVTP 3645

Query: 1145 AVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTV--MATGAPCSAGPLLGPSMAREPG 1202
            +    +V T     ++ + S   T  ++  ST   V  M+   P        PS + E  
Sbjct: 3646 SSDASAVKT-ETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPS-STEAE 3703

Query: 1203 GRSPAFVQLAPLSSKVRLSSP-------SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMA 1255
                + V     S+K   ++P       S+  L         S  A T +  GA  P+  
Sbjct: 3704 DVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQEL 3763

Query: 1256 PVCESLQGGSPSTT--------VTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATT 1307
             +   +   SP+T+        +T     A +  S+ VT    +P  +  E  +T   TT
Sbjct: 3764 TLETMI---SPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTT 3820

Query: 1308 SNAGSAQ-------------RVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAG 1354
            ++A   Q                  P       G T   T A +   +   +    P A 
Sbjct: 3821 TSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSWNEKEKSTPSAP 3880

Query: 1355 RPCETHQTTSTGTTMSV-SVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPT 1413
               E   + S  T   V S  ++L    +    +ESG   + +   +P    A  +   T
Sbjct: 3881 WITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSWKSSPYERIA-PSESTT 3939

Query: 1414 QRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVES----TQGDSVNITSS 1469
             +   +P      T T  T   VTS+  ++    PA S   ++ S    T      I S 
Sbjct: 3940 DKEAIHP-----STNTVETTGWVTSSEHASHSTIPAHSASSKLTSPVVTTSTREQAIVSM 3994

Query: 1470 SAIT--------TTVSSTLTRAVTTVT----QSTPVPGPSVPPPEELQVSPGPRQQL--- 1514
            S  T        T  +S LT  +  V+     S+      +  P    ++ GPR ++   
Sbjct: 3995 STTTWPESTRARTEPNSFLTIELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITSS 4054

Query: 1515 -----------------PPRQLLQSASTALMGESAEVLSASQT----------PELPAAV 1547
                             P   + + ++   M ES  ++ A QT          P L  + 
Sbjct: 4055 KRISSSFLAQSMRSSDSPSEAITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSA 4114

Query: 1548 DLSSTGEPSSGQESAGSAVVATV-------VVQPPPPTQSEVDQLSLPQELMAEAQAGTT 1600
              S TG P +  +    +   T+         QP PP+  E    S    + A       
Sbjct: 4115 TASWTGTPLATTQRFTYSEKTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNI 4174

Query: 1601 TLMVTGLTPEEL--AVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEA 1658
             L   G +P       +      +    T +   ++++             GE + T EA
Sbjct: 4175 LLTSQGHSPSSTPPVTSVFLSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEA 4234

Query: 1659 A 1659
            +
Sbjct: 4235 S 4235



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 86/396 (21%), Positives = 159/396 (40%), Gaps = 23/396 (5%)

Query: 401   DIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTT 460
             D  A+  T    T  PV    ++   S   A    A  P T+    +L   +P  P   T
Sbjct: 11685 DTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVT 11744

Query: 461   IQVLPTVPGSSISVPTAARTQGVP--AVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTS 518
              Q+  +   +S +VPT   + G+P    L  T P+  T           Q  +   ++T 
Sbjct: 11745 SQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTI 11804

Query: 519   LP-AGVRMVVPTQSAQG--TVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT 575
              P A     +PTQ+     T++ +      ++  A+   + +  P S+ P   +    +T
Sbjct: 11805 RPGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLSTHPGTET----ST 11860

Query: 576   IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIIT- 634
             ++ T  ++ G   L  T  +A+S    ++ +T  L  + A  G S +S T    + + + 
Sbjct: 11861 MIPTSTLSLG--LLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSW 11918

Query: 635   -VHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQ 693
                 S +VT     +   TV G    T+TL+ S +  P  ++    +    ++++T  V+
Sbjct: 11919 NTETSPSVTSVGPPEFSRTVTG---TTMTLIPSEMPTPPKTSHGEGVSPT-TILRTTMVE 11974

Query: 694   TSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGI 753
              + +    S+  V +   T   L AG++   +T+         + T  +    +  I   
Sbjct: 11975 ATNLATTGSSPTVAKTTTTFNTL-AGSLFTPLTTPGMSTLASESVTSRTSYNHRSWISTT 12033

Query: 754   SSV-----SPSTTKPGTTTIIKTIPMSAIITQAGAT 784
             SS      +P+T+ P T+T    I  S+I +   AT
Sbjct: 12034 SSYNRRYWTPATSTPVTSTFSPGISTSSIPSSTAAT 12069



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 173/885 (19%), Positives = 308/885 (34%), Gaps = 112/885 (12%)

Query: 955  SQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCS 1014
            S PT+ +L+T     +A P  D   S L   T    T+T  I       V   T+     
Sbjct: 11   SSPTR-SLMTGSRSTKATPEMD---SGLTGATLSPKTSTGAIV------VTEHTLPFTSP 60

Query: 1015 NPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNG----- 1069
            +    +  +      T ++       P+ T        Q  + SL     G  +      
Sbjct: 61   DKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPAT 120

Query: 1070 SVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGA 1129
            S+V   S+P   T  T    T   +T  +  +   S P  E + T  T T+TT   S   
Sbjct: 121  SMVSGLSSPRTRTSSTEGNFTKEASTYTLTVET-TSGPVTEKY-TVPTETSTTEGDSTET 178

Query: 1130 NHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSA 1189
                D R      T  +   + +T + E A  S +  +T  T + +   T  + G   S+
Sbjct: 179  PW--DTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYSS 236

Query: 1190 GPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGA 1249
               L P     P  R    ++L   ++    SSP     P       +ST+A   SS   
Sbjct: 237  FLDLSPKGT--PNSRGETSLELILSTTGYPFSSPE----PGSAGHSRISTSAPLSSSASV 290

Query: 1250 GEPRMAPVCESLQGGSPSTTVT---VTALEALLCPSATV--TQVCSNPPCETHETGTT-- 1302
             + +++    S+  G   T+     V    A   P++ +  +   SN         +T  
Sbjct: 291  LDNKISET--SIFSGQSLTSPLSPGVPEARASTMPNSAIPFSMTLSNAETSAERVRSTIS 348

Query: 1303 --NTATTSNAGSAQRVCS-NPPCETHETGTTHTATTATSNG-GTGQPEGGQQPPAGRPCE 1358
               T + S   +A+ + + +   ET +  +TH A T  S   G+    GG          
Sbjct: 349  SLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGT--------- 399

Query: 1359 THQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCS 1418
               +TS  TT S S   +  +  + H T     E     S+TP   +A            
Sbjct: 400  ---STSALTTTSPSTTLVSEETNTHHSTSGKETEGTLNTSMTPLETSA------------ 444

Query: 1419 NPPCETHETGT---THTATTVTSNMSS-----NQDPPPAASDQGEVESTQGDSVNITSSS 1470
             P  E+  T T   T   TT+ S + S     +  P       G     Q  S     SS
Sbjct: 445  -PGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSS 503

Query: 1471 AITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQ------LLQSAS 1524
             I    +S+ ++A +  ++ST          + ++ SP  + + PP        +  S  
Sbjct: 504  DILRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVP 563

Query: 1525 TALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQ 1584
            + + G +    S+++   L      +  GE ++G  +   AV   + +     T+     
Sbjct: 564  SVVSGFTTLKTSSTKGIWLEETSADTLIGESTAGPTTHQFAVPTGISMTGGSSTRGSQGT 623

Query: 1585 LSLPQELMAEAQAGTTTLMVTGLTPEEL--AVTAAAEAAAQAAATEEAQALAIQAVLQAA 1642
              L     A ++      + T   P  +  AV+  A  ++    T+ +  +    + + +
Sbjct: 624  THLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETS 683

Query: 1643 --QQAVMGTG-----EPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALV 1695
              Q +    G      P++T    ++      GH         +T+IP++ +   L   V
Sbjct: 684  SLQSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKI------STSIPLLSSASVLEDKV 737

Query: 1696 QQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPST-ATES 1754
                   +      HH  T ++    +   P I +        T PS+  L   T +  +
Sbjct: 738  -------SATSTFSHHKATSSI----TTGTPEISTK-------TKPSSAVLSSMTLSNAA 779

Query: 1755 LAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPP 1799
             +P     A  P+   SP+  + A ++  ++   E+    P++ P
Sbjct: 780  TSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTD-SPNIHP 823


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score =  132 bits (331), Expect = 4e-30
 Identities = 282/1307 (21%), Positives = 435/1307 (33%), Gaps = 225/1307 (17%)

Query: 364  PPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPAN 423
            P PP   QL    +   +V W    T+ +  L       P++  T  SPT  P+  +PA 
Sbjct: 1202 PQPPTTPQLPTTGSRPTQV-WPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPL--LPAT 1258

Query: 424  PPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGV 483
               S   A++    +P T V     PQA    P T T++   T P  + +   A  +   
Sbjct: 1259 LTSSKPTASSGEPPRPTTAV----TPQATSGLPPTATLRSTATKPTVTQATTRATASTAS 1314

Query: 484  PAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQM 543
            PA       Q+TT T +    PA+ +G +P    +LP      +P  +A  T  G  P  
Sbjct: 1315 PATTSTA--QSTTRTTMTLPTPAT-SGTSP----TLPKSTNQELPGTTATQTT-GPRPT- 1365

Query: 544  SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVS 603
                A        Q   P+      +    TT   T   TP TT  P T   A SPV  +
Sbjct: 1366 ---PASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPT---AGSPVPST 1419

Query: 604  NPATRMLKTAAAQVGTSVSSATNTSTR-----PIITVHKSGTVTVAQQAQVVTTVVGGVT 658
             P T     A     T     T   T        +    + TV     AQ+ T+      
Sbjct: 1420 GPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSA----- 1474

Query: 659  KTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPA 718
                   S  S P G+                P  T   TG   T P         P+  
Sbjct: 1475 -------SNHSAPTGT--------------IPPPTTLKATGSTHTAP---------PI-- 1502

Query: 719  GTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKP-----GTTTIIKTIP 773
                         PTT  T+   S   T  T   + S + ST  P      TTTI     
Sbjct: 1503 ------------TPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPT 1550

Query: 774  MSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQV 833
             +   T    T   +S     P T  +    +S   +   +     K  T +        
Sbjct: 1551 STRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTY-------- 1602

Query: 834  VLKGAPGQPGTILRT-VPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVST 892
                 P  P T L T VP     LVTP T + + P    +    +      GT+    + 
Sbjct: 1603 ---PTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTL 1659

Query: 893  SLAGAGGHSTSASLATPITTLGTIATLSS--QVINPTAITVSAAQTTLTAAGGLTTPTIT 950
               G    ST  +    +TT GT   LSS       T++    + T    A   +T  IT
Sbjct: 1660 KATG----STHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNIT 1715

Query: 951  MQPVSQPTQVTLITAPSGVEAQ----------PVHDLPVSILASPTTEQPTATVTIADSG 1000
              P S  T    +T     +++           +H    S      T   T ++T   + 
Sbjct: 1716 PNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTS 1775

Query: 1001 QGDVQPGTVT-----------LVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFV 1049
             G   P   T               +PP  T    +T   T T       +P P+     
Sbjct: 1776 TGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTT 1835

Query: 1050 CDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPC 1109
                    S  TS V     +V+         TH    T  AT+A+ + +   G   PP 
Sbjct: 1836 LPTH--VPSFSTSLVTPSTHTVI-------IPTH----TQMATSASIH-SMPTGTIPPPT 1881

Query: 1110 ETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTR 1169
                TG+T+TA     +     Q  +  + A  + ++   + +T   E    S +    +
Sbjct: 1882 TIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPK 1941

Query: 1170 QTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLP 1229
             TS  + T     T A  S  P   P     P   S  F    P+++    S  +    P
Sbjct: 1942 HTSTGTRTPVAHTTSASSSRLPT--PFTTHSPPTGSSPFSSTGPMTA---TSFQTTTTYP 1996

Query: 1230 AGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVC 1289
               H                    + P   SL   +PST   +      +  SA++    
Sbjct: 1997 TPSHPQTTLPT------------HVPPFSTSLV--TPSTHTVIITTHTQMATSASIHSTP 2042

Query: 1290 SN---PPCETHETGTTNTA---TTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTG 1343
            +    PP     TG+T+TA   T + +G++Q         TH + +T TA+++  +  + 
Sbjct: 2043 TGTVPPPTTLKATGSTHTAPPMTVTTSGTSQ---------THSSFSTATASSSFISSSSW 2093

Query: 1344 QPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQA 1403
             P+     P   P  T                 LP  +S+   V +  +++++ S +P A
Sbjct: 2094 LPQNSSSRPPSSPITTQ----------------LPHLSSATTPVSTTNQLSSSFSPSPSA 2137

Query: 1404 GTALLAPFPTQRVCSNPPCETHETGTT--------HTATTVTSNMSSNQDPPPAASDQGE 1455
             + + +  P+    S+P   +   GT+        H+ T  + + SS    P  AS    
Sbjct: 2138 PSTVSSYVPSSH--SSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHPTTASVSA- 2194

Query: 1456 VESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLP 1515
                   S    SS A +TT+ +TL   +     S+P    ++ P   + VSP P   L 
Sbjct: 2195 -------SPLFPSSPAASTTIRATLPHTI-----SSPFTLSALLPISTVTVSPTPSSHLA 2242

Query: 1516 ------PRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVAT 1569
                  P     +AST      +   + S++  L   V  S     +SG     ++ V  
Sbjct: 2243 SSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGFVSLTSGVTGIPTSPVTN 2302

Query: 1570 VVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTA 1616
            +  + P PT S   +              T++L   G TP    V++
Sbjct: 2303 LTTRHPGPTLSPTTRFL------------TSSLTAHGSTPASAPVSS 2337



 Score =  105 bits (261), Expect = 6e-22
 Identities = 265/1171 (22%), Positives = 407/1171 (34%), Gaps = 191/1171 (16%)

Query: 559  IPPSSA--PTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQ 616
            +PP++   PT   +P  TT  +   V P T T   T+ + SS    + P+     T A+ 
Sbjct: 1197 MPPTTPQPPTTPQLP--TTGSRPTQVWPMTGT-STTIGLLSS----TGPSPSSNHTPASP 1249

Query: 617  VGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSAL 676
              T +  AT TS++P  +  +    T A   Q  +    G+  T TL  +        A 
Sbjct: 1250 TQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATS----GLPPTATLRSTATKPTVTQAT 1305

Query: 677  ISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTII 736
                    S   T   Q++  T      P T    T   LP  T  +L       P T  
Sbjct: 1306 TRATASTASPATTSTAQSTTRTTMTLPTPATS--GTSPTLPKSTNQEL-------PGT-- 1354

Query: 737  TTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPI 796
            T TQ +G    P     S+  P+T +PG  T     P +   TQ   T   ++P  ++P 
Sbjct: 1355 TATQTTGPRPTPA----STTGPTTPQPGQPTR----PTATETTQTRTTTEYTTP--QTPH 1404

Query: 797  TIITTKVMTSGTGAPAK-IITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRT-VPMGGV 854
            T  T    T+G+  P+   +TA    AT               P  P T L T VP    
Sbjct: 1405 T--THSPPTAGSPVPSTGPVTATSFHAT----------TTYPTPSHPETTLPTHVPPFST 1452

Query: 855  RLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLG 914
             LVTP T + + P    +    +      GT+     T+L   G   T+  + TP TT G
Sbjct: 1453 SLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPP--TTLKATGSTHTAPPI-TP-TTSG 1508

Query: 915  TIATLSSQVIN--PTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQ 972
            T    SS   N  PT++    + T        +T TIT  P S  T+             
Sbjct: 1509 TSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRT------------ 1556

Query: 973  PVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTT 1032
                 PV+   S T+ +P    T      G           S+P   T     T+  TTT
Sbjct: 1557 -----PVAHTNSATSSRPPPPFTTHSPPTG-----------SSPFSSTGPMTATSFKTTT 1600

Query: 1033 VVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTAT 1092
                   HPQ T    V      + SLVT                P   T  T T     
Sbjct: 1601 TYPT-PSHPQTTLPTHV---PPFSTSLVT----------------PSTHTVITPTHAQMA 1640

Query: 1093 TATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVA 1152
            T+ S  +   G   PP     TG+T+TA T   +     Q  +    A  + ++   + +
Sbjct: 1641 TSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSS 1700

Query: 1153 TGALEAAQGSKSQCQTRQTSATSTTMTVMATG----------APCSAGPLLGPSMAREPG 1202
            T   EA   S +      TS  +  MTV  +G          A  S       S    P 
Sbjct: 1701 THHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPE 1760

Query: 1203 GRSPAFVQLAPLSSKVRLSSP-------SIKDLPAGRHSHAVSTAAMTRSSVG------- 1248
              S +   + P  +     +P       +   LP    +H+  T     SS G       
Sbjct: 1761 VTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSF 1820

Query: 1249 -------------AGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSN---P 1292
                            P   P   S    +PST   +      +  SA++  + +    P
Sbjct: 1821 QTTTTYPTPSHPHTTLPTHVP-SFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPP 1879

Query: 1293 PCETHETGTTNTA---TTSNAGSAQRVCSNPPCET-----HETGTTH---TATTATSNGG 1341
            P     TG+T+TA   T + +G++Q   S    +T     + T +TH      T+T+N  
Sbjct: 1880 PTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNIT 1939

Query: 1342 TGQPEGGQQPPAGR-----------PCETHQT-------TSTGTTMSVSVGALLPDATSS 1383
                  G + P              P  TH         +STG   + S        T S
Sbjct: 1940 PKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPS 1999

Query: 1384 H--RTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMS 1441
            H   T+ + +   +   VTP   T ++      ++ ++    +  TGT    TT+ +  S
Sbjct: 2000 HPQTTLPTHVPPFSTSLVTPSTHTVIITTH--TQMATSASIHSTPTGTVPPPTTLKATGS 2057

Query: 1442 SNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV-----SSTLTRAVTTVTQSTPVPGP 1496
            ++  PP   +  G  ++    S    SSS I+++      SS+   +    TQ   +   
Sbjct: 2058 THTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSA 2117

Query: 1497 SVPPPEELQV----SPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSST 1552
            + P     Q+    SP P         + S+ ++    S  V ++S     P      S+
Sbjct: 2118 TTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSS 2177

Query: 1553 GEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMA----EAQAGTTTLMVTGLT 1608
            G  SS      +A V+   + P  P  S   + +LP  + +     A    +T+ V+   
Sbjct: 2178 GSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPISTVTVSPTP 2237

Query: 1609 PEELAVTAAA--EAAAQAAATEEAQALAIQA 1637
               LA +  A        A+T  A A + Q+
Sbjct: 2238 SSHLASSTIAFPSTPRTTASTHTAPAFSSQS 2268



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 227/996 (22%), Positives = 344/996 (34%), Gaps = 149/996 (14%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGIT-------------LLP 449
            P TA +  + T  P PS P     +  P  +   V P T   IT               P
Sbjct: 1421 PVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAP 1480

Query: 450  QAAPAPPTT--------TTIQVLPTVPGSSISVPTAARTQGVPAVL-----KVTGPQAT- 495
                 PPTT        T   + PT  G+S    ++  T   P  L         P+ T 
Sbjct: 1481 TGTIPPPTTLKATGSTHTAPPITPTTSGTS-QAHSSFSTNKTPTSLHSHTSSTHHPEVTP 1539

Query: 496  TGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAA 555
            T T  +T  P S   + PV  T+     R   P  +      GSSP  S     A +   
Sbjct: 1540 TSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPF-TTHSPPTGSSPFSSTGPMTATSFKT 1598

Query: 556  TQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTL--PATVKVASSPVMVSNPATRMLKTA 613
            T   P  S P   ++P       T  VTP T T+  P   ++A+S  + S P      T 
Sbjct: 1599 TTTYPTPSHPQT-TLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMP------TG 1651

Query: 614  AAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVG-------------GVTKT 660
                 T++ +  +T T P +T+  SGT           T                  T T
Sbjct: 1652 TIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTST 1711

Query: 661  ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720
              +  +P S       ++  G       T   ++S  T + ST   +    T  P    T
Sbjct: 1712 TNITPNPTSTGTPPMTVTTSG-------TSQSRSSFSTAKTSTSLHSHTSSTHHPEVTST 1764

Query: 721  ILKLVT---SADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI 777
                +T   ++ G  T +  TT A+ +   PT    ++ SP T   GTT I  T P++A 
Sbjct: 1765 STTSITPNHTSTGTRTPVAHTTSATSSRL-PT--PFTTHSPPT---GTTPISSTGPVTAT 1818

Query: 778  ITQAGATGVTSS----------PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGH-- 825
              Q   T  T S          P   + +   +T  +   T        ++  + TG   
Sbjct: 1819 SFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIP 1878

Query: 826  -----GQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPV---TVSAVKPAVTTLVVKGT 877
                    G T       P   GT          +  T +   T S   P VT      T
Sbjct: 1879 PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPT---ST 1935

Query: 878  TGVTTLGTVTGTVSTSLAGAGGHSTSAS---LATPITTLGTIATLSSQVINPTAITVSAA 934
            T +T   T TGT  T +A    H+TSAS   L TP TT     T SS   +   +T ++ 
Sbjct: 1936 TNITPKHTSTGT-RTPVA----HTTSASSSRLPTPFTTHSP-PTGSSPFSSTGPMTATSF 1989

Query: 935  QTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHD---LPVSILASPTTEQPT 991
            QTT T     + P  T+     P   +L+T  +       H       SI ++PT   P 
Sbjct: 1990 QTTTTYPTP-SHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGTVPP 2048

Query: 992  ATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQ------PTQ 1045
             T   A        P TVT   ++   +TH + +T TA+++ +++    PQ      P+ 
Sbjct: 2049 PTTLKATGSTHTAPPMTVT---TSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSS 2105

Query: 1046 VQFVCDRQEAAASLVTSTVGQQNGS--------------VVRVCSNPPCETHETGTTNTA 1091
                     ++A+   ST  Q + S              V    S+P   +   GT+++ 
Sbjct: 2106 PITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSF 2165

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAM-SSVGANHQRDARRACAAGTPAVIRIS 1150
             +A  +       S+    TH T  + +A+    SS  A+    A       +P  +   
Sbjct: 2166 VSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSAL 2225

Query: 1151 VATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPA--F 1208
            +    +  +    S   +   +  ST  T  +T    +       S +     R P   F
Sbjct: 2226 LPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTSGF 2285

Query: 1209 VQLA------PLSSKVRLS--------SPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRM 1254
            V L       P S    L+        SP+ + L +   +H  + A+   SS+G   P  
Sbjct: 2286 VSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSLTAHGSTPASAPVSSLGTPTPTS 2345

Query: 1255 APVC------ESLQGGSPSTTVTVTALEALLCPSAT 1284
              VC      E +        VTVT  E     +A+
Sbjct: 2346 PGVCSVREQQEEITFKGCMANVTVTRCEGACISAAS 2381



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 78/322 (24%), Positives = 113/322 (35%), Gaps = 47/322 (14%)

Query: 1317 CSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSV--- 1373
            CS      HE G        T    T QP    Q P      T     TGT+ ++ +   
Sbjct: 1180 CSQDEYFDHEEGVCVPCMPPT----TPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSS 1235

Query: 1374 ----------------GALLP-DATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRV 1416
                              LLP   TSS  T  SG       +VTPQA T+ L P  T R 
Sbjct: 1236 TGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQA-TSGLPPTATLRS 1294

Query: 1417 CSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV 1476
             +  P  T  T T  TA+T +        P   ++ Q    +T       TS ++ T   
Sbjct: 1295 TATKPTVTQAT-TRATASTAS--------PATTSTAQSTTRTTMTLPTPATSGTSPTLPK 1345

Query: 1477 SSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLS 1536
            S+      TT TQ+T   GP   P      + GP    P +    +A+      +    +
Sbjct: 1346 STNQELPGTTATQTT---GPRPTPAS----TTGPTTPQPGQPTRPTATETTQTRTTTEYT 1398

Query: 1537 ASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQ 1596
              QTP    +   + +  PS+G  +A S    T    P  P      + +LP  +   + 
Sbjct: 1399 TPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHP------ETTLPTHVPPFST 1452

Query: 1597 AGTTTLMVTGLTPEELAVTAAA 1618
            +  T    T +TP    +  +A
Sbjct: 1453 SLVTPSTHTVITPTHAQMATSA 1474



 Score = 38.5 bits (88), Expect = 0.068
 Identities = 68/277 (24%), Positives = 87/277 (31%), Gaps = 40/277 (14%)

Query: 1536 SASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEA 1595
            S +QTP LPA +  SS    SSG+              PP PT +   Q +         
Sbjct: 1248 SPTQTPLLPATLT-SSKPTASSGE--------------PPRPTTAVTPQAT-------SG 1285

Query: 1596 QAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGE--PM 1653
               T TL  T   P     T  A A+  + AT        +  +     A  GT    P 
Sbjct: 1286 LPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPK 1345

Query: 1654 DTSE--AAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHH- 1710
             T++     T TQ      +     G  T  P   T+       Q +   E    Q  H 
Sbjct: 1346 STNQELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHT 1405

Query: 1711 -HLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAP--SNTFVAPQPV 1767
             H P  A +P  S       S        T        P T   +  P  S + V P   
Sbjct: 1406 THSPPTAGSPVPSTGPVTATS-----FHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTH 1460

Query: 1768 VVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKA 1804
             V +P   Q A   T  +N     G  P  PP   KA
Sbjct: 1461 TVITPTHAQMA---TSASNHSAPTGTIP--PPTTLKA 1492



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 44/185 (23%), Positives = 68/185 (36%), Gaps = 27/185 (14%)

Query: 1741 PSTVALLPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPP 1800
            P+   LLP+T T S   +++   P+P    +P   QA + L   A  + S   KP +   
Sbjct: 1249 PTQTPLLPATLTSSKPTASSGEPPRPTTAVTP---QATSGLPPTAT-LRSTATKPTVTQA 1304

Query: 1801 PSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGTVPDYNQLKKQELQPGT 1860
             ++A     +          T   +T         +P+    GT P   +   QEL PGT
Sbjct: 1305 TTRATASTASPATTSTAQSTTRTTMT---------LPTPATSGTSPTLPKSTNQEL-PGT 1354

Query: 1861 AYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISK--------SPDGAHLTWEP 1912
                  A      R   +  +   T  PG P  P A + ++        +P   H T  P
Sbjct: 1355 -----TATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSP 1409

Query: 1913 PSVTS 1917
            P+  S
Sbjct: 1410 PTAGS 1414


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score =  129 bits (323), Expect = 4e-29
 Identities = 305/1450 (21%), Positives = 504/1450 (34%), Gaps = 191/1450 (13%)

Query: 400  YDIPATAATATSPTPNPVPSVPANPPKSPA-PAAAAPAVQPLTQVGITLLPQAAP---AP 455
            Y  P +  T  SP       V      S + P +    V P +     L  ++     + 
Sbjct: 2331 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2390

Query: 456  PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMR-------PASQ 508
            P +T   V P  P +S+           PA    T     + T  +T         PAS 
Sbjct: 2391 PGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST 2450

Query: 509  AGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSS----- 563
                P T+T+   G        S+  T    SP  S  + L   +  ++  P S+     
Sbjct: 2451 QTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTL 2510

Query: 564  --APTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSV 621
              +PT  S+   +T   T   +P  T  PAT          S+  +    T+ +Q G++ 
Sbjct: 2511 PGSPTTPSLSEKSTTFYTSPRSPDATLSPATT--------TSSGVSEESSTSHSQPGSTH 2562

Query: 622  SSATNTST------RPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISV----- 670
            ++A   ST      R   T H S   T        TT  G   ++ T   SP S      
Sbjct: 2563 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALS 2622

Query: 671  PGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADG 730
            PG +  +S  G+  +   + P  T       ST        + G + A T    V S+ G
Sbjct: 2623 PGSTTALS-FGQESTTFHSSPGSTHTTLFPDST-------TSSGIVEAST---RVHSSTG 2671

Query: 731  KPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSP 790
             P T    T +  + T P + G S+     T P +T    + P +A      +T    SP
Sbjct: 2672 SPRT----TLSPASSTSPGLQGESTTFQ--THPASTHTTPSPPSTATAPVEESTTYHRSP 2725

Query: 791  GIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVP 850
            G             T  T  PA   T+      GH ++     +   +P   GT   +  
Sbjct: 2726 G------------STPTTHFPASSTTS------GHSEKST---IFHSSPDASGTTPSSAH 2764

Query: 851  MGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPI 910
                      T S    + T+ +  G+T +TTL   T T   S A    +S+  S  T +
Sbjct: 2765 S---------TTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTL 2815

Query: 911  TT-------LGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV--- 960
            +        +G  +T S      T  TVS A TT       +T   +  P S  T V   
Sbjct: 2816 SPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPR 2875

Query: 961  TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADS-----GQGDVQ---PGTVTLV 1012
            +  T+  G E    H  P S   +  TE  T +    +S          Q   P T+T  
Sbjct: 2876 STTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTA 2935

Query: 1013 -----CSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQ-FVCDRQEAAASLVTSTVGQ 1066
                  +  P  +  TGTT +   +  + L G   P+++     +      S  T ++ +
Sbjct: 2936 DLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSE 2995

Query: 1067 QNGSVVRVCSNP-----PCETHETGTTNTATTATSNMAGQH-----------GCSNPPCE 1110
            ++ +      +P     P  T  +G +  ++T+ S     H           G S  P  
Sbjct: 2996 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA 3055

Query: 1111 THETGTTNTAT-----TAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAA---QGS 1162
            +H +  +  AT     T  SS+G              T  +   ++ +G +EA+     S
Sbjct: 3056 SHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSS 3115

Query: 1163 KSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSS 1222
                 T  T A+ST+  +        + P    +    PG  + A V+++        S+
Sbjct: 3116 TGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPG-TTAAPVEVSTTYHSRPSST 3174

Query: 1223 PSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV--CESLQGGSPSTT-VTVTALEALL 1279
            P+     +         +    SS GA    + P     S+  G P+T+ ++  + E   
Sbjct: 3175 PTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTA 3234

Query: 1280 CPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHET-GTTHTATTATS 1338
             P +T T   S      + +  +   T S A +     S     +H   G+THT      
Sbjct: 3235 LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP-- 3292

Query: 1339 NGGTGQPEGGQQPPAGR--PCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAA 1396
             G T  P   Q+  A    P  T  T S G+T + S+G   P++T+ H    S  E    
Sbjct: 3293 -GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG---PESTTFHSGPGS-TETTLL 3347

Query: 1397 PSVTPQAG-----TALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAAS 1451
            P  T  +G     T + +   +     +P   T   G + T  +  ++  +   PP   S
Sbjct: 3348 PDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 3407

Query: 1452 DQGEVESTQGDSVNITSSSAITTTVSSTLTRAV-TTVTQSTPVPGPSVPPPEELQVSPGP 1510
               E+ +T   S + T ++  + + S+TL R+  +T   S+PV   + P P         
Sbjct: 3408 AFVELSTTSHGSPSSTPTTHFSAS-STTLGRSEESTTVHSSPVATATTPSP--------- 3457

Query: 1511 RQQLPPRQLLQSASTALMGESAEVLS---ASQTPELPAAVDLSSTGEPSSGQESAGSAVV 1567
                      +S ++ L+ ES    S   ++QT   P +   S  GE S+   S+ +  +
Sbjct: 3458 ---------ARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTI 3508

Query: 1568 ATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAAT 1627
            ++     P  T + V++ +      +     TT    +  T      + A+ ++  A  T
Sbjct: 3509 SSA----PSTTSALVEEPTSYHS--SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT 3562

Query: 1628 EEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSA---EGQEGQATTIPI 1684
                A +  +VL         +   M+T+    + T   L   S          ATT+  
Sbjct: 3563 IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLS- 3621

Query: 1685 VLTQQELAALVQQQQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTV 1744
                    A      + E           T   A  DS   P +  +     +    +  
Sbjct: 3622 -------PASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 3674

Query: 1745 ALLPSTATES 1754
             LLP++ T S
Sbjct: 3675 TLLPASTTTS 3684



 Score =  124 bits (311), Expect = 9e-28
 Identities = 310/1337 (23%), Positives = 470/1337 (35%), Gaps = 250/1337 (18%)

Query: 405  TAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVL 464
            +++T     P    S P++   SPAP+    A      V ++    ++P+   TT     
Sbjct: 409  SSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAF-----VKLSTTYHSSPSSTPTTHFSAS 463

Query: 465  PTVPGSSI------SVPTAARTQGVPAVLKVTG--------------------PQATTGT 498
             T  G S       S P A  T   PA    +G                    P+++T T
Sbjct: 464  STTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST-T 522

Query: 499  PLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQ------SAQGTVIGSSPQMSGMAALAAA 552
               +   A+  G    T +S P+    +  T       S + T    S  +SG +  + A
Sbjct: 523  SGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKA 582

Query: 553  ------AAATQKIPPSSAPTVL-----SVPAGTTIVKTMAVTPGTTTLPATVKVA----S 597
                  A AT  +P  S P+VL       P  +  ++T A+ PG+TT P   + +    S
Sbjct: 583  SHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL-PGSTTKPGLSEKSTTFYS 641

Query: 598  SPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP--IITVHKSGTVTVAQQAQVVTTVVG 655
            SP    +P T  L  +    G S  S T+ S RP    T    G+ T+   +Q  T    
Sbjct: 642  SP---RSPDTTHLPASMTSSGVSEESTTSHS-RPGSTHTTAFPGSTTMPGLSQESTASHS 697

Query: 656  GVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGP 715
                T T + SP     GS   S+LG   +   ++P  T       +T   + +++   P
Sbjct: 698  SPGPTDTTL-SP-----GSTTASSLGPEYTTFHSRPGSTETTLLPDNT-TASGLLEASMP 750

Query: 716  L------------PAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKP 763
            +            PAG+     T+  G+ TT  +   +      P     + V PSTT  
Sbjct: 751  VHSSTRSPHTTLSPAGS-----TTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSH 805

Query: 764  GTTTIIKTIPMSAIITQAG----ATGVTSSPGIKSPITIITTKVMTSGTG---------- 809
            G+ + I T  +SA  T +G    +T   SSPG    +    +   TSG G          
Sbjct: 806  GSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT-TSGRGEESTTSHSST 864

Query: 810  ------APAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVS 863
                  AP+     V +  + H   G T       P    T  R+            T +
Sbjct: 865  THTISSAPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSGRSEESTASHSSQDATGT 922

Query: 864  AVKPAVTT---LVVKGTTGVTTLGTVTGTV---STSLAGAGGHSTS--ASLATPITTLGT 915
             V PA +T   L+ + TT   + G++  T    ST+  G    ST+  +S  +P TTL  
Sbjct: 923  IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSP 982

Query: 916  IATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVH 975
             +T SS V   +  + S   +T T A     P  T  P       T  ++P   +     
Sbjct: 983  ASTTSSGVSEESTTSRSRPGSTHTTA----FPDSTTTPGLSRHSTTSHSSPGSTDTTL-- 1036

Query: 976  DLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVA 1035
             LP S   S  +++ T + + + S    + PG+ T +       T  +   +T TT    
Sbjct: 1037 -LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTL--- 1092

Query: 1036 NLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTAT 1095
                 P  T    + +    A++ V S+ G    ++    S  P    E+    T   +T
Sbjct: 1093 ----FPDSTTSSGIVE----ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 1144

Query: 1096 SNMAGQHGCSNPPCETHET-----GTTNTATTAMSSVGANHQRDA----RRACAAGTPAV 1146
                     +  P E   T     G+T T     SS  + H   +        A+GT   
Sbjct: 1145 HTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 1204

Query: 1147 IRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPG-GRS 1205
               S  +G        + +  T + S  ST +T +             P     PG   +
Sbjct: 1205 SAHSTTSG--------RGESTTSRISPGSTEITTL-------------PGSTTTPGLSEA 1243

Query: 1206 PAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGS 1265
                  +P S    LS  S+  L  G  S        +RS  G+    ++P   +  G S
Sbjct: 1244 STTFYSSPRSPTTTLSPASMTSLGVGEES------TTSRSQPGSTHSTVSPASTTTPGLS 1297

Query: 1266 PSTTVTVT----ALEALLCPSATVTQV-------CSNPPCETHETGTTNTATTSNAGSAQ 1314
              +T   +    + E  + P +T T V         + P  TH T  T  +TTS      
Sbjct: 1298 EESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES 1357

Query: 1315 RVCSNPPCETHETGTTHTATTA----------TSNGGTGQP-----------EGGQQPPA 1353
                  P  T +TG   T TTA          +S+G TG              G   P  
Sbjct: 1358 TAFPGSPAST-QTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSR 1416

Query: 1354 GRPCETHQTTSTG--TTMSVS-------VGALLPDATSSHRTVESGLEVAAAPSVTPQAG 1404
              P  T  TT  G  TT S+S            PDAT S  T  S      + +   Q G
Sbjct: 1417 LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPG 1476

Query: 1405 TALLAPFP---TQRVCSNPPCETHET-GTTHTATTVTSNMSSN--QDPPPAASDQGEVES 1458
            +     FP   T    S  P  +H + G+T    +  S  +S+  Q      S  G+ E+
Sbjct: 1477 STHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTET 1536

Query: 1459 TQGDSVNITSS--SAITTTVSS------TLTRAVTT----------------VTQSTPVP 1494
            T      ITS    A T T SS      TLT A +T                 + +TP P
Sbjct: 1537 TLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSP 1596

Query: 1495 GPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSS--- 1551
              +   P E+  +   R    P     ++ST L G S E  +   +P         +   
Sbjct: 1597 PGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL-GRSEESTTVHSSPGATGTALFPTRSA 1655

Query: 1552 ----TGEPSSGQESAGS 1564
                 GEP++   S+GS
Sbjct: 1656 TSVLVGEPTTSPISSGS 1672



 Score =  119 bits (297), Expect = 4e-26
 Identities = 315/1542 (20%), Positives = 542/1542 (35%), Gaps = 206/1542 (13%)

Query: 405  TAATATSPTPNPVPSVPANPPKSPAPAAAAPAV-QPLTQVGITLLPQAAPAPPTTTT--I 461
            T A+       PV S   +P  + +PA +     +  T           PAPPTTT+  +
Sbjct: 3351 TTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV 3410

Query: 462  QVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521
            ++  T  GS  S PT   +               + T L     ++    +PV   + P+
Sbjct: 3411 ELSTTSHGSPSSTPTTHFS--------------ASSTTLGRSEESTTVHSSPVATATTPS 3456

Query: 522  GVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVL---SVPAGTTIVK 578
              R        + T   SSP           +  T   P S   +     S  + ++   
Sbjct: 3457 PARSTTSGLVEESTTYHSSP----------GSTQTMHFPESDTTSGRGEESTTSHSSTTH 3506

Query: 579  TMAVTPGTTT--LPATVKVASSPVMVS-----NPATRMLKTAAAQVGTSVSSATNTSTRP 631
            T++  P TT+  +       SSP   +     + +T   ++  +    S   AT T   P
Sbjct: 3507 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 3566

Query: 632  I-----ITVHKSGTVTVAQQAQVVTTVVGGVT------KTITLVKSPIS----VPGGSAL 676
                  + + +S T  ++  +   T + G  T      K+ T   SP S    +   S  
Sbjct: 3567 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT 3626

Query: 677  ISNLGKVMSVVQTKP--VQTSAVTGQASTGPVTQIIQTKGPLPAGT---ILKLVTSADGK 731
             S + +  +   ++P    T+A     +T  +++   T    P  T   +L   T+  G 
Sbjct: 3627 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGS 3686

Query: 732  PTTIITTTQASGAGTKPTILGISSVSP------STT---KPGTT--TIIKTIPMSAIITQ 780
                 +TT  S +G+  T L   S +       STT    PG+T  T+      S+ I +
Sbjct: 3687 SQE--STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 3744

Query: 781  AG-----ATGV---------TSSPGIKSPITIITTK-VMTSGTGAPAKIITA-VPKIATG 824
            A      +TG          ++SPG++   T   T    T  T +P    TA V +  T 
Sbjct: 3745 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTY 3804

Query: 825  HGQQGVTQVV------LKGAPGQPGTILRTVP--MGGVRLVTPVTVSAVKPAVTTLVVKG 876
            H   G T               +  TI  + P   G        T S    + T+ +  G
Sbjct: 3805 HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 3864

Query: 877  TTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITT-------LGTIATLSSQVINPTAI 929
            +T +TTL   T T   S A    +S+  S  T ++        +G  +T S      T  
Sbjct: 3865 STEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHS 3924

Query: 930  TVSAAQTTLTAAGGLTTPTITMQPVSQPTQV---TLITAPSGVEAQPVHDLPVSILASPT 986
            TVS A TT       +T   +  P S  T V   +  T+    E    H  P S   +  
Sbjct: 3925 TVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLF 3984

Query: 987  TEQPTATVTIADS-----GQGDVQ---PGTVTLV-----CSNPPCETHETGTTNTATTTV 1033
            TE  T +    +S          Q   P T+T        +  P  +  TGT  +   + 
Sbjct: 3985 TEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARST 4044

Query: 1034 VANLGGHPQPTQVQ-FVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTAT 1092
             + L G   P+++     +      S  T ++ +++ +      +P        T + AT
Sbjct: 4045 TSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA------TLSPAT 4098

Query: 1093 TATSNMAGQHGCSNP-PCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            T +S ++ +   S+  P  TH T   ++ TT+    G + +     +    T A +    
Sbjct: 4099 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS----GLSQEPTTSHSSQGSTEATLSPGS 4154

Query: 1152 ATGALEAAQGSKSQCQTRQTSAT-------STTMTVMATGAPCSAGPL---LGPSMAREP 1201
             T +    Q +        T  T       ++ +   +T    S G L   L P+ +   
Sbjct: 4155 TTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTST 4214

Query: 1202 GGRSPAFV-QLAPLSSKVRLSSPSIKDLPAG----RHSHAVSTAA--MTRSSVGAGEPRM 1254
            G +  +   Q  P SS    S PS   +P       HS   ST     + SS   G    
Sbjct: 4215 GLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEE 4274

Query: 1255 APVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTA------TTS 1308
            +    S  G + +      +  ++L    T + + S     T   G+T TA      TT 
Sbjct: 4275 STTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTF 4334

Query: 1309 NAGSAQRVCSNPPCETHETGTTHTATTATSNGG----------TGQPEGGQQPPAGR--P 1356
             +       +  P  T  +G +  +TT+ S  G          T  P   Q+  A    P
Sbjct: 4335 YSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP 4394

Query: 1357 CETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAG-----TALLAPF 1411
              T  T S G+T + S+G   P++T+ H +  S  E    P  T  +G     T + +  
Sbjct: 4395 GSTDTTLSPGSTTASSLG---PESTTFHSSPGS-TETTLLPDNTTASGLLEASTPVHSST 4450

Query: 1412 PTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSA 1471
             +     +P   T   G + T  +  ++  +   PP   S   E+ +T   S + T ++ 
Sbjct: 4451 GSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTH 4510

Query: 1472 ITTTVSSTLTRAV-TTVTQSTPVPGPSVPPPEE------------LQVSPGPRQQLPPRQ 1518
             + + S+TL R+  +T   S+PV   + P P                 SPG  Q +    
Sbjct: 4511 FSAS-STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTM---H 4566

Query: 1519 LLQSASTALMGESAEVLSASQTPELPAAVDLSS--TGEPSSGQESAGSAVVATVVVQPPP 1576
              +S +T+  GE +    +S T  + +A   +S    EP+S   S GS            
Sbjct: 4567 FPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHF------ 4620

Query: 1577 PTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQ 1636
            P  S     S        +Q  T T+++   +   + +  +  +   + + E        
Sbjct: 4621 PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGST 4680

Query: 1637 AVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLT----QQELA 1692
                 ++++      P  T     + +   LG  S E     ++ +    T    +   +
Sbjct: 4681 TTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGR-SEESTTVHSSPVATATTPSPARSTTS 4739

Query: 1693 ALVQQQ-QLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTA 1751
             LV++      +    Q  H P  + A   S       S+  + ++    +T AL+    
Sbjct: 4740 GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPT 4799

Query: 1752 TESLAPSN--TFVAPQPVVVASPAKLQAAATLTEVANGIESL 1791
            +   +P +  T   P+    +  ++   A+  +   NGI  L
Sbjct: 4800 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPL 4841



 Score =  117 bits (293), Expect = 1e-25
 Identities = 286/1297 (22%), Positives = 433/1297 (33%), Gaps = 187/1297 (14%)

Query: 454  APPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAP 513
            +P +T T     +   S  S  + A      A   +  P  +T + L+     S      
Sbjct: 1971 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 2030

Query: 514  VTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAG 573
            +  T+LP       P  S + T   SSP+    A   + A+ T       + T  S P  
Sbjct: 2031 METTALPGST--TTPGLSEKSTTFHSSPRSP--ATTLSPASTTSSGVSEESTTSHSRPGS 2086

Query: 574  TTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATN-TSTRPI 632
            T    T A    TTT   +    +S     +  T +L  +    G S  S T+ +S    
Sbjct: 2087 T---HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2143

Query: 633  ITVHKSGTVTVAQQAQVVTT-----------------VVGGVTKTITLVKSPISVPG--- 672
             T    G+ T     Q  TT                    G+ +  T V S    P    
Sbjct: 2144 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2203

Query: 673  --GSALISNLGKVMSVVQTKPVQTSAVTGQASTG--PV---TQIIQTKGPLPAGTILKLV 725
               S+    L    +  QT P  T       ST   PV   T   ++ G  P        
Sbjct: 2204 SPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASS 2263

Query: 726  TSADGKPTTIITTTQASGAGTKP-----TILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780
            T++     + I  +    +GT P     T  G    + S   PG+T I  T+P S     
Sbjct: 2264 TTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT-TLPGSTTTPG 2322

Query: 781  AGATGVTSSPGIKSPITIITTKVMTS-GTGAPAKII---------TAVPKIATGHGQQGV 830
                  T     +SP T ++   MTS G G  +            T  P   T  G    
Sbjct: 2323 LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEE 2382

Query: 831  TQVVLKGAPGQPGT-ILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGT 889
            +  V   +PG   T +    P   VR   P T  + +PA T      TT  T   T +G 
Sbjct: 2383 STTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHS-RPASTH-----TTLFTEDSTTSGL 2436

Query: 890  VSTSLAGAGGH-STSASLATPITT--LGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT 946
               S A  G   ST   L   +TT  LG  +T        T  T+S A++T +   G +T
Sbjct: 2437 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGEST 2496

Query: 947  PTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQP 1006
            P+        P+     T P       + +   +   SP +  P AT++ A +    V  
Sbjct: 2497 PSRL-----SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS--PDATLSPATTTSSGVSE 2549

Query: 1007 GTVTLVCSNPPCETHETGTTNTATTTVVA--NLGGHPQPTQVQFVCDRQEAAASLVTSTV 1064
             + T    + P  TH T   ++ TT  ++  +   H  P       D     AS  TS  
Sbjct: 2550 ESST--SHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST----DTTLLPASTTTSGP 2603

Query: 1065 GQQNGSVVRVCSNPPCETHET-GTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTA 1123
             Q++ +           +H + G+T+TA +  S  A   G  +    +    T  T    
Sbjct: 2604 SQESTT-----------SHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 2652

Query: 1124 MSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             ++     +   R   + G+P    +S A+      QG  +  QT   S  +T       
Sbjct: 2653 STTSSGIVEASTRVHSSTGSPRTT-LSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTA 2711

Query: 1184 GAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRL--SSPSIKDL-PAGRHSHAVSTA 1240
             AP         S    P    PA    +  S K  +  SSP      P+  HS      
Sbjct: 2712 TAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRG 2771

Query: 1241 AMTRSSVGAGEPRMAPVCESL--------------QGGSPSTTVTVTALEAL-------- 1278
              T S +  G   +  +  S                  SP+TT++  ++ +L        
Sbjct: 2772 ESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTT 2831

Query: 1279 -----------LCPSATVTQ--------VCSNPPCETHETGTTNTATTSNAGSAQRVCSN 1319
                       + P++T T         V S+ P  T  T    + TTS  G       +
Sbjct: 2832 SRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHS 2891

Query: 1320 PPCETHETGTTHTATT------------ATSNGGTGQPEGGQQPPAGRPCETHQTT--ST 1365
             P  TH T  T  +TT            + ++  TG P        G    T  ++  ST
Sbjct: 2892 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 2951

Query: 1366 GTTMS---VSVGALLPDATSSHRTVESGLEVAAAPS---------------VTPQAGTAL 1407
            GTT+S    +   L+ ++T S R   S  E    P                 +P++  A 
Sbjct: 2952 GTTLSPARSTTSGLVGESTPS-RLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 3010

Query: 1408 LAPFPT--QRVCSNPPCETHETGTTHTA----TTVTSNMSSNQDPPPAASDQGEVESTQG 1461
            L+P  T    V         + G+THT     +T TS +S  Q+P  + S QG  E+T  
Sbjct: 3011 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLS--QEPTASHSSQGSTEATLS 3068

Query: 1462 DSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQ 1521
                        +T +S+L +  TT   S+P    +   P++   S       P      
Sbjct: 3069 PG----------STTASSLGQQSTTF-HSSPGDTETTLLPDDTITSGLVEASTPTHSSTG 3117

Query: 1522 SASTALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSE 1581
            S  T L   S+      +      +   SS   PS    +A    V+T     P  T + 
Sbjct: 3118 SLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPT- 3176

Query: 1582 VDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAA 1618
                S     +  ++  TT     G T   L  T +A
Sbjct: 3177 -THFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 3212



 Score =  110 bits (275), Expect = 1e-23
 Identities = 357/1670 (21%), Positives = 558/1670 (33%), Gaps = 221/1670 (13%)

Query: 410  TSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPG 469
            +SP       +P +   S    A+ P       +  TL P ++ +           + P 
Sbjct: 1529 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPS 1588

Query: 470  SSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQA---GKAPVTVTSLPAGVRMV 526
            SS + P+   T   P  +  T     + TP      +S      +   TV S P      
Sbjct: 1589 SSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTA 1648

Query: 527  V-PTQSAQGTVIG---SSPQMSGMAALAAAAAATQKI-----------PPSSAPTVLSVP 571
            + PT+SA   ++G   +SP  SG     A   +T               P S  T LS P
Sbjct: 1649 LFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS-P 1707

Query: 572  AGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP 631
            A TT       +  + + P +    + P   + P      TA+     S  +  +  +  
Sbjct: 1708 ASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTT 1767

Query: 632  IITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKP 691
              ++    T   +      TT++   T    L+++   V       S+ G   + +   P
Sbjct: 1768 ASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVH------SSTGSPHTTLS--P 1819

Query: 692  VQTSAVTGQAST---GPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP 748
              ++   G+++T    P ++      P      ++L T++ G P++  TT  ++ +    
Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS---- 1875

Query: 749  TILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG----ATGVTSSPGI------------ 792
            T LG S    STT   +     T P  A  T +G    +T   SSPG             
Sbjct: 1876 TTLGRSE--ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTA 1933

Query: 793  --KSPITIITTKVMTSGTGAPAKIITAVPKIATG-HGQQGVTQVVLKGAPGQPGTILRTV 849
              +S  +  +    T    +P    +A+ +  T  H   G T       P    T  R+ 
Sbjct: 1934 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATT--HFPDSSTTSGRSE 1991

Query: 850  PMGGVRLVTPVTVSAVKPAVTT---LVVKGTTGVTTLGTVTGTV---STSLAGAGGHSTS 903
                       T + V PA +T   L+ + TT   + G++  T    ST+  G    ST+
Sbjct: 1992 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT 2051

Query: 904  --ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVT 961
              +S  +P TTL   +T SS V   +  + S   +T T A     P  T  P       T
Sbjct: 2052 FHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTA----FPDSTTTPGLSRHSTT 2107

Query: 962  LITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETH 1021
              ++P   +      LP S   S  +++ T + +   S    + PG+ T +       T 
Sbjct: 2108 SHSSPGSTDTTL---LPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTF 2164

Query: 1022 ETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCE 1081
             +   +T TT         P  T    + +    A++ V S+ G    ++    S  P  
Sbjct: 2165 HSSPGSTHTTLF-------PDSTTSSGIVE----ASTRVHSSTGSPRTTLSPASSTSPGL 2213

Query: 1082 THETGTTNTATTATSNMAGQHGCSNPPCETHET-----GTTNTATTAMSSVGANHQRDAR 1136
              E+    T   +T         +  P E   T     G+T T     SS  + H   + 
Sbjct: 2214 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 2273

Query: 1137 ----RACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPL 1192
                   A+GT      S  +G        + +  T + S  ST +T +           
Sbjct: 2274 IFHSSPDASGTTPSSAHSTTSG--------RGESTTSRISPGSTEITTL----------- 2314

Query: 1193 LGPSMAREPG-GRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGE 1251
              P     PG   +      +P S    LS  S+  L  G  S        +RS  G+  
Sbjct: 2315 --PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEES------TTSRSQPGSTH 2366

Query: 1252 PRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAG 1311
              ++P   +  G S  +T                  V S+ P  T  T    T TTS  G
Sbjct: 2367 STVSPASTTTPGLSEESTT-----------------VYSSSPGSTETTVFPRTPTTSVRG 2409

Query: 1312 SAQRVCSNPPCETHETGTTHTATTA----TSNGGTGQPEGGQQ--PPAGRPCETHQTTST 1365
                   + P  TH T  T  +TT+     S    G P   Q   P      +  + ++T
Sbjct: 2410 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 2469

Query: 1366 GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425
              + S S G  L  A    R+  SGL   + PS         L+P  T+   + P   T 
Sbjct: 2470 FPSSSGSTGTTLSPA----RSTTSGLVGESTPS--------RLSPSSTE-TTTLPGSPTT 2516

Query: 1426 ETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAV- 1484
             + +  + T  TS  S +    PA +    V      S +   S+  T    ST T  + 
Sbjct: 2517 PSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLS 2576

Query: 1485 --TTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPE 1542
              +T + S+P    +   P     S   ++         S  TAL   S   LS  Q   
Sbjct: 2577 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQE-- 2634

Query: 1543 LPAAVDLSSTGEPSSGQ-------ESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEA 1595
                   S+T   S G        +S  S+ +     +    T S    LS         
Sbjct: 2635 -------STTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 2687

Query: 1596 QAGTTTLMV----TGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGE 1651
            Q  +TT       T  TP   +  + A A  + + T      +       A     G  E
Sbjct: 2688 QGESTTFQTHPASTHTTP---SPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSE 2744

Query: 1652 PMDT--SEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAAL---VQQQQLQEAQAQ 1706
                  S   A+ T     H +  G+ G++TT  I     E+  L        L EA   
Sbjct: 2745 KSTIFHSSPDASGTTPSSAHSTTSGR-GESTTSRISPGSTEITTLPGSTTTPGLSEASTT 2803

Query: 1707 -QQHHHLPTEALAPADSLN-DPAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAP 1764
                   PT  L+PA   +     ES       G+  STV+   ST T  L+  +T    
Sbjct: 2804 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS-PASTTTPGLSEEST---- 2858

Query: 1765 QPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPSKAPMKKENQWF-DVGVIKGTNV 1823
              V  +SP      +T T V     +  V+ + P      P       F +     G   
Sbjct: 2859 -TVYSSSP-----GSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLTE 2912

Query: 1824 MVTHYFLPPDD------AVPSDDDLG----TVPDYNQLKKQELQPGTAYKFRVAGINACG 1873
              T +   P        A  +  DLG    T P  +      L P  +    + G +   
Sbjct: 2913 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPS 2972

Query: 1874 RGPFSEISAFKTCLPGFPGAPCAIKIS----KSPDGAHLTWEPPSVTSGKIIEYSVYLAI 1929
            R   S  S   T LPG P  P   + S     SP     T  P + TS  + E S   + 
Sbjct: 2973 R--LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEES---ST 3027

Query: 1930 QSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSSSLSNAHIDYTTKPAI 1979
              SQ G    ++ P       +   P+ S   Q S+ +      TT  ++
Sbjct: 3028 SHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSL 3077



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 285/1361 (20%), Positives = 482/1361 (35%), Gaps = 206/1361 (15%)

Query: 446  TLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRP 505
            TL P ++ +P          T P S+ + P+   T   P     T  ++   TP  T  P
Sbjct: 3759 TLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTP-TTHFP 3817

Query: 506  ASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP 565
            AS                       S + T+  SSP  SG    +A +  + +       
Sbjct: 3818 ASSTTSG-----------------HSEKSTIFHSSPDASGTTPSSAHSTTSGR----GES 3856

Query: 566  TVLSVPAGTTIVKTMAVTPGTTTLP----ATVKVASSPVMVSNPATRMLKTAAAQVGTSV 621
            T   +  G+T + T+   PG+TT P    A+    SSP    +P T +   +   +G   
Sbjct: 3857 TTSRISPGSTEITTL---PGSTTTPGLSEASTTFYSSP---RSPTTTLSPASMTSLGVGE 3910

Query: 622  SSATNTS----TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSP---ISVPGGS 674
             S T+ S    T   ++   + T  +++++  V +   G T+T    +S    +     +
Sbjct: 3911 ESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPT 3970

Query: 675  ALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSAD--GKP 732
               S      + + T+   TS +T +++  P +    T+  LPA      +T+AD   + 
Sbjct: 3971 TFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA-STQTGLPA-----TLTTADLGEES 4024

Query: 733  TTIITTTQASGAGTKP---TILGI------SSVSPSTTKPGTTTIIKTIPMSAIITQAGA 783
            TT  +++ ++G    P   T  G+      S +SPS+T+   TT +   P +  +++   
Sbjct: 4025 TTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTE---TTTLPGSPTTPSLSEKST 4081

Query: 784  TGVTS--SPGIK-SPITIITTKVM----TSGTGAPAKIITAVP----------KIATGHG 826
            T  TS  SP    SP T  ++ V     TS +   +   TA P          +  T H 
Sbjct: 4082 TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHS 4141

Query: 827  QQGVTQVVLK------GAPGQPGTILRTVPMGGVRLVTP---VTVSAVKPAVTTLVVKG- 876
             QG T+  L        + GQ  T   + P      + P   +T   V+ +  T    G 
Sbjct: 4142 SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 4201

Query: 877  --TTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAIT---- 930
              TT      T TG    S       S+S +  +P +T      +S+   +  + T    
Sbjct: 4202 LHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTH 4261

Query: 931  VSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQP 990
             SA+ TTL  +   TT  +   P +  T +    + + V        P+S  ++ TT  P
Sbjct: 4262 FSASSTTLGRSEESTT--VHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALP 4319

Query: 991  TATVTIADSGQGDV---QPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGH----PQP 1043
             +T T   S +       P +     S  P  T  +G +  +TT+       H    P  
Sbjct: 4320 GSTTTAGLSEKSTTFYSSPRSPDTTLS--PASTTSSGVSEESTTSHSRPGSMHTTAFPSS 4377

Query: 1044 TQVQFVCDRQEAAASLVTST-VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQH 1102
            T +  V     A+ S   ST      GS       P   T  +   +T TT   +     
Sbjct: 4378 TTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTAS 4437

Query: 1103 GCSNPPCETHETGTTNTATTAMSSVGAN-------------HQRDARRACAAGTPAVIRI 1149
            G        H +  T +  T +S  G+              + +D   A    T A + +
Sbjct: 4438 GLLEASTPVHSS--TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVEL 4495

Query: 1150 SVATGALEAAQGSKSQCQTRQTSATSTTM-----TVMATGAPCSAGPLLGPSMAREPGGR 1204
            S  +       GS S   T   SA+STT+     +     +P +      P+ +   G  
Sbjct: 4496 STTS------HGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV 4549

Query: 1205 SPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQG- 1263
              +    +   S   +  P   +  +GR   + ++ + T  ++ +     + + E     
Sbjct: 4550 EESTTYHSSPGSTQTMHFPE-SNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY 4608

Query: 1264 -GSPSTTVTVTALEALLCPSATVTQVCSNPPCETHE----TGTTNTATTSNAGSAQRVCS 1318
              SP +T T         P ++ T   S     +H     TGT      S         +
Sbjct: 4609 HSSPGSTATTHF------PDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGEST 4662

Query: 1319 NPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTST-------GTTMSV 1371
              P  +    TT    + T+ G + +       P+  P      +ST        TT+  
Sbjct: 4663 TSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHS 4722

Query: 1372 SVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCE--THETGT 1429
            S  A     + +  T    +E + A   +P  G+     FP     S    E  T  + T
Sbjct: 4723 SPVATATTPSPARSTTSGLVEESTAYHSSP--GSTQTMHFPESSTASGRSEESRTSHSST 4780

Query: 1430 THTATTVTSNMSSN-QDPPPAASDQGEVESTQGDSVNITS--SSAITTTVSSTLTRAVT- 1485
            THT ++  S  S+  ++P    S  G + +T     + TS  S   T + SS  T  +T 
Sbjct: 4781 THTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITP 4840

Query: 1486 --------------------------TVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQL 1519
                                      T+  +   PG S         S  P Q L P  +
Sbjct: 4841 LPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASM 4900

Query: 1520 LQSASTALMGESAEVLS---ASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPP 1576
                S+++ GE   + S   ++ T   PA+   S   + S+   S   +   T  + P  
Sbjct: 4901 ---TSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETT--LSPGS 4955

Query: 1577 PTQSEVDQ-----LSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQ 1631
             T S   Q      S P   ++     +TT  V GL+ EE     ++  + +  A   + 
Sbjct: 4956 ITTSSFAQEFTTPHSQPGSALSTVSPASTT--VPGLS-EESTTFYSSPGSTETTAFSHSN 5012

Query: 1632 ALAIQAVLQAAQQAVMGTGEPMDT-SEAAATVTQAELGHLS 1671
             ++I      +QQ+      P  T +   AT+T  ++G  S
Sbjct: 5013 TMSIH-----SQQSTPFPDSPGFTHTVLPATLTTTDIGQES 5048



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 319/1529 (20%), Positives = 509/1529 (33%), Gaps = 242/1529 (15%)

Query: 435  PAVQPLTQVGI--TLLPQA---APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV 489
            P   P+T   +  T LP +   A     +TT    P  P  ++S P    + GV      
Sbjct: 252  PKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLS-PARTTSSGVSEKSTT 310

Query: 490  T----GPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS--PQM 543
            +    GP  T   P  T  P     +      S+P        T  + GT   SS  P+ 
Sbjct: 311  SHSRPGPTHTIAFPDSTTMPG--VSQESTASHSIPGST----DTTLSPGTTTPSSLGPES 364

Query: 544  SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVS 603
            +   + +     T ++P ++  T   +   +T V +   +P TT  P+     SS     
Sbjct: 365  TTFHS-SPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPS-----SSTTHEG 416

Query: 604  NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITL 663
             P T     ++     + S  T+   +   T H S + T        +T +G   ++  +
Sbjct: 417  EPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV 476

Query: 664  VKSPISV-----PGGSALISNLGKVMSV------VQTKPVQTSAVTGQASTGPVT---QI 709
              SP++      P  SA   ++ +  +        QT     S+ T   S    T     
Sbjct: 477  HSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGST 536

Query: 710  IQTKGPLPAGTILKLVTS----------------------------ADGKPTTIITTTQA 741
              TK   P+ T     TS                            +   P  + TT   
Sbjct: 537  THTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLP 596

Query: 742  SGAGTKPTILGISSVSP-------------STTKPG----------------TTTIIKTI 772
            +G+ T   ++G S+ SP             STTKPG                TT +  ++
Sbjct: 597  AGS-TPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASM 655

Query: 773  PMSAIITQA-------GATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGH 825
              S +  ++       G+T  T+ PG  S      ++  T+   +P    T +   +T  
Sbjct: 656  TSSGVSEESTTSHSRPGSTHTTAFPG--STTMPGLSQESTASHSSPGPTDTTLSPGSTTA 713

Query: 826  GQQGVTQVVLKGAPGQPGTIL---RTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT---G 879
               G         PG   T L    T   G +    PV  S   P  TTL   G+T   G
Sbjct: 714  SSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPH-TTLSPAGSTTRQG 772

Query: 880  VTTL---------------GTVTGTVSTSLAGAG-----------GHSTSASLATPITTL 913
             +T                 T +  V  S    G             ST++ L    TT 
Sbjct: 773  ESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTY 832

Query: 914  GTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQP 973
             +    +  +  P + T S      T +   TT TI+  P    T   L+  P+   + P
Sbjct: 833  HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAP---STTSALVEEPTSYHSSP 889

Query: 974  ----VHDLPVSILASPTTEQPTATVTIADSGQGDVQP--GTVTLVCSNPPCETHETGTTN 1027
                    P S   S  +E+ TA+ +  D+    V P   T +++          +G+  
Sbjct: 890  GSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSME 949

Query: 1028 TATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGT 1087
            T          G  + +       R  A      ST             + P  TH T  
Sbjct: 950  TTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAF 1009

Query: 1088 TNTATTATSNMAGQHGCSNP--------PCETHETGTTNTATTAMSSVGANHQRDARRAC 1139
             ++ TT   +       S+P        P  T  +G +  +TT+ SS G+        A 
Sbjct: 1010 PDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTD-----TAL 1064

Query: 1140 AAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAG---PLLGPS 1196
            + G+   +     +    +  GS +       S TS+ +   +T    S G     L P+
Sbjct: 1065 SPGSTTALSFGQESTTFHSNPGS-THTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA 1123

Query: 1197 MAREPG--GRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRM 1254
             +  PG  G S AF Q  P S+    S PS    P       V  +     S G+     
Sbjct: 1124 SSTSPGLQGESTAF-QTHPASTHTTPSPPSTATAP-------VEESTTYHRSPGSTPTTH 1175

Query: 1255 APVCESLQGGSPSTTVTVTALEAL-LCPSATVTQVCSNPPCETHETGTTNTATTSNAGSA 1313
             P   +  G S  +T+  ++ +A    PS+  +         T      +T  T+  GS 
Sbjct: 1176 FPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 1235

Query: 1314 QRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPA-GRPCETHQTTSTGTTMSVS 1372
                 +    T  +      TT +    T    G +   +  +P  TH T S  +T   +
Sbjct: 1236 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAST---T 1292

Query: 1373 VGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHET----- 1427
               L  ++T+ + +     E    P  T    T++    PT     + P  TH T     
Sbjct: 1293 TPGLSEESTTVYSSSRGSTETTVFPHSTT---TSVHGEEPT--TFHSRPASTHTTLFTED 1347

Query: 1428 ----GTTHTATTVTSNMSSNQDPPPA---ASDQGEVESTQGDSVNITS---SSAITTTV- 1476
                G T  +T    + +S Q   PA    +D GE  +T   S   T    S A +TT  
Sbjct: 1348 STTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG 1407

Query: 1477 ---SSTLTRAVTTVTQSTPVPG-PSVPPPEELQVS--PGPRQQLPPRQLLQSASTALMGE 1530
                ST +R   + T++T +PG P+ P   E   +    PR    P   L  A+T   G 
Sbjct: 1408 LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS---PDATLSPATTTSSGV 1464

Query: 1531 SAEVLSASQTP---ELPAAVDLSSTG----EPSSGQESAGSAVVATVVVQPPPPTQSEVD 1583
            S E  ++   P      A  D ++T     EP++   S GS       + P   T S + 
Sbjct: 1465 SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGS---TEATLSPGSTTASSLG 1521

Query: 1584 QLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAA------TEEAQALAIQA 1637
            Q    Q     +  G T    T L P++   +   EA+    +      T    A +  A
Sbjct: 1522 Q----QSTTFHSSPGDTE---TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSA 1574

Query: 1638 VLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQ 1697
             LQ             DT+ +    T A +   +       +T      T    A+    
Sbjct: 1575 GLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTP-----TTHFSASSTTL 1629

Query: 1698 QQLQEAQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAP 1757
             + +E+            AL P  S     +     + ++     T AL  ST T  L+ 
Sbjct: 1630 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSE 1689

Query: 1758 SNT--FVAPQ-PVVVASPAKLQAAATLTE 1783
             +T  + +P+ P    SPA   ++    E
Sbjct: 1690 KSTTFYSSPRSPDTTLSPASTTSSGVSEE 1718



 Score = 89.4 bits (220), Expect = 3e-17
 Identities = 228/1070 (21%), Positives = 379/1070 (35%), Gaps = 152/1070 (14%)

Query: 410  TSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPG 469
            +SP       +P +   S    A+ P       +  TL P ++ +           + P 
Sbjct: 4169 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPS 4228

Query: 470  SSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPT 529
            SS + P+   T  VP  +  T     + TP      +S         T+L          
Sbjct: 4229 SSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASS---------TTL---------G 4270

Query: 530  QSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTL 589
            +S + T + SSP  +G A     +A +  +     PT   + +G+T  +T A+   TTT 
Sbjct: 4271 RSEESTTVHSSPGATGTALFPTRSATSVLV---GEPTTSPISSGST--ETTALPGSTTTA 4325

Query: 590  PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP---IITVHKSGTVT--VA 644
              + K  +      +P T +   +    G S  S T+ S RP     T   S T    V+
Sbjct: 4326 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS-RPGSMHTTAFPSSTTMPGVS 4384

Query: 645  QQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTG 704
            Q++    +  G    T+    SP     GS   S+LG   +   + P  T       +T 
Sbjct: 4385 QESTASHSSPGSTDTTL----SP-----GSTTASSLGPESTTFHSSPGSTETTLLPDNT- 4434

Query: 705  PVTQIIQTKGPL------------PAGTILKLVTSADGKPTTIITTTQASGAGTKPTILG 752
              + +++   P+            PAG+     T+  G+ TT  +   +      P    
Sbjct: 4435 TASGLLEASTPVHSSTGSPHTTLSPAGS-----TTRQGESTTFQSWPNSKDTTPAPPTTT 4489

Query: 753  ISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPA 812
             + V  STT  G+ +   T   SA  T  G +        +   T+ ++ V T+ T +PA
Sbjct: 4490 SAFVELSTTSHGSPSSTPTTHFSASSTTLGRS--------EESTTVHSSPVATATTPSPA 4541

Query: 813  KIITA--VPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVT 870
            +  T+  V +  T H   G TQ +    P    T  R          T  T+S+     +
Sbjct: 4542 RSTTSGLVEESTTYHSSPGSTQTM--HFPESNTTSGRGEESTTSHSSTTHTISSAPSTTS 4599

Query: 871  TLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAIT 930
             LV + T+  ++ G+   T     +   G S  ++           A+ SSQ    T I 
Sbjct: 4600 ALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST-----------ASHSSQDATGT-IV 4647

Query: 931  VSAAQTTLTAAGGLTTPTI---TMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTT 987
            + A  TT    G  TT  I   +M+  + P   T  T     ++   H  P S   +PTT
Sbjct: 4648 LPARSTTSVLLGESTTSPISSGSMETTALPGSTT--TPGLSEKSTTFHSSPSS---TPTT 4702

Query: 988  EQPTATVTIADSGQGDVQPGTVTLVCSNP-PCETHETGTTNTATTTVVANLGGHPQPTQV 1046
                ++ T+  S +        T V S+P    T  +   +T +  V  +   H  P   
Sbjct: 4703 HFSASSTTLGRSEES-------TTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 4755

Query: 1047 QFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSN 1106
            Q +   + + AS  +      + S     S+PP         +T +         H    
Sbjct: 4756 QTMHFPESSTASGRSEESRTSHSSTTHTISSPP---------STTSALVEEPTSYHSSPG 4806

Query: 1107 PPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQC 1166
                TH   ++ T+  +  S  ++   D        TP     + +    E+     S  
Sbjct: 4807 SIATTHFPESSTTSGRSEESTASHSSPDTNGI----TPLPAHFTTSGRIAESTTFYIS-- 4860

Query: 1167 QTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIK 1226
                  +  TT+   AT    SA   +  S +R P         L+P S    ++S SI 
Sbjct: 4861 ----PGSMETTLASTATTPGLSAKSTILYSSSRSPD------QTLSPAS----MTSSSIS 4906

Query: 1227 DLPAGRHSHAVS--TAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSAT 1284
              P   +S A S  T A   S+  +G  + +    S  G + +T          L P + 
Sbjct: 4907 GEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETT----------LSPGSI 4956

Query: 1285 VTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQ 1344
             T   +      H    +  +T S A +     S     T  +    T TTA S+  T  
Sbjct: 4957 TTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSE-ESTTFYSSPGSTETTAFSHSNTMS 5015

Query: 1345 PEGGQQPP-AGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEV-----AAAPS 1398
                Q  P    P  TH T    T  +  +G    ++T+ H + ++         + A  
Sbjct: 5016 IHSQQSTPFPDSPGFTH-TVLPATLTTTDIG---QESTAFHSSSDATGTTPLPARSTASD 5071

Query: 1399 VTPQAGTALLAPFPTQR----VCSNPPCETHETGTTHTATTVTSNMSSNQ 1444
            +  +  T  ++P PT        S+    T E+ T HT+ + TS + S +
Sbjct: 5072 LVGEPTTFYISPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTE 5121



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 257/1194 (21%), Positives = 395/1194 (33%), Gaps = 194/1194 (16%)

Query: 618  GTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALI 677
            G + S++T +S+ P  T    G          VT + G       L  S  S     + +
Sbjct: 175  GNTTSASTPSSSDPFTTFSDYGVS--------VTFITGSTATKHFLDSSTNSGHSEESTV 226

Query: 678  SNLGKVMSVVQTKPVQ--TSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTI 735
            S+ G   +     P    TS   G+  T P+T        LP  T          K TT 
Sbjct: 227  SHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGST---TTAGLSEKSTTF 283

Query: 736  ITTTQASGAGTKPTILGISSVSPSTT----KPGTTTIIKTIPMSAIITQAGATGVTSSPG 791
             ++ ++      P     S VS  +T    +PG T  I      A        GV+    
Sbjct: 284  YSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI------AFPDSTTMPGVSQEST 337

Query: 792  IKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPM 851
                I   T   ++ GT  P+ +    P+  T H   G T+               T   
Sbjct: 338  ASHSIPGSTDTTLSPGTTTPSSL---GPESTTFHSSPGYTKTTRLPD--------NTTTS 386

Query: 852  GGVRLVTPVTVSAVKPAVTTLVVKGTT---GVTTLGTVTGTVSTSLAGAGGHSTSASLAT 908
            G +   TPV  S   P  T      TT     TT  +   +  TS A +G  S    L+T
Sbjct: 387  GLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLST 446

Query: 909  PITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSG 968
                     T  S   +      SA+ TTL      +TP  +    +  T     +A SG
Sbjct: 447  ---------TYHSSPSSTPTTHFSASSTTL-GHSEESTPVHSSPVATATTPPPARSATSG 496

Query: 969  --VEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET------ 1020
               E+   H  P S   + T   P ++ T   S +     G+ T   S+ P  T      
Sbjct: 497  HVEESTAYHRSPGS---TQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHT 553

Query: 1021 ---HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEA-----AASLVTSTVGQQNGSVV 1072
                  G+T T      + + G  + ++         A     A S  +  VG    S +
Sbjct: 554  SYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPI 613

Query: 1073 RVCSNP----PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVG 1128
               S      P  T + G +  +TT  S+       ++ P     +G +  +TT+ S  G
Sbjct: 614  SSGSMETTALPGSTTKPGLSEKSTTFYSSPRSP-DTTHLPASMTSSGVSEESTTSHSRPG 672

Query: 1129 ANHQR-----------DARRACAAGTPAVIRISVATGALEAAQ-GSKSQCQTRQTSATST 1176
            + H                   +  +P     +++ G+  A+  G +      +  +T T
Sbjct: 673  STHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTET 732

Query: 1177 TMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRL-------SSPSIKDLP 1229
            T+    T    +A  LL  SM      RSP    L+P  S  R        S PS KD  
Sbjct: 733  TLLPDNT----TASGLLEASMPVHSSTRSP-HTTLSPAGSTTRQGESTTFHSWPSSKDT- 786

Query: 1230 AGRHSHAVSTAAMTR-SSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQV 1288
              R +   +T+A    S+   G P   P        + STT  +         S   TQ 
Sbjct: 787  --RPAPPTTTSAFVEPSTTSHGSPSSIPTTHI---SARSTTSGLVEESTTYHSSPGSTQT 841

Query: 1289 CSNPPCET-----HETGTTNTATTSNAGSAQRVCS---NPPCETH----ETGTTHTATTA 1336
               P  +T      E+ T++++TT    SA    S     P   H     T TTH   ++
Sbjct: 842  MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSS 901

Query: 1337 TSNGGTGQ---PEGGQQPPAGRPCETHQTTST----GTTMSVSVGAL----LPDAT---- 1381
            T++G + +       Q            TTS      TT  +S G++    LP +T    
Sbjct: 902  TTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG 961

Query: 1382 ---------SSHRTVESGLEVAAAPS--VTPQAGTALLAPFPTQRVC-----SNPPCETH 1425
                     SS R+  + L  A+  S  V+ ++ T+   P  T         + P    H
Sbjct: 962  LSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRH 1021

Query: 1426 ET------GTTHT----ATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITT- 1474
             T      G+T T    A+T TS  S       ++S   +   + G +  ++     TT 
Sbjct: 1022 STTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 1081

Query: 1475 ---------------TVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQL 1519
                           T SS +  A T V  ST  P  ++ P      SPG          
Sbjct: 1082 HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS--STSPG---------- 1129

Query: 1520 LQSASTALMGESAEVLSASQTPELPAA-VDLSSTGEPSSGQ--------ESAGSAVVATV 1570
            LQ  STA     A   +    P    A V+ S+T   S G          S  S      
Sbjct: 1130 LQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKS 1189

Query: 1571 VVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEA 1630
             +    P  S     S         ++ T+ +         L  +      ++A+ T  +
Sbjct: 1190 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYS 1249

Query: 1631 QALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLS--AEGQEGQATTI 1682
               +    L  A    +G GE   TS +    T + +   S    G   ++TT+
Sbjct: 1250 SPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTV 1303



 Score = 64.7 bits (156), Expect = 9e-10
 Identities = 188/944 (19%), Positives = 316/944 (33%), Gaps = 138/944 (14%)

Query: 886  VTG-TVSTSLAGAGGHSTSASLATPITTLG---------TIATLSSQVINPTAITVSAAQ 935
            +TG TV+TS+ G    +++ S + P TT           T +T +   ++ +  +  + +
Sbjct: 164  ITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNSGHSEE 223

Query: 936  TTLTAAGGLTTPTITMQPVSQPTQVTL---ITAPSGVEAQPVHDLPVSILASPTTEQPTA 992
            +T++ +G   T T T+ P    T V +    T+P    +     LP S   +  +E+ T 
Sbjct: 224  STVSHSGPGATGT-TLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTT 282

Query: 993  TVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDR 1052
              +   S    + P   T   S+   E   T  +    T  +A     P  T +  V   
Sbjct: 283  FYSSPRSPDRTLSPARTT---SSGVSEKSTTSHSRPGPTHTIA----FPDSTTMPGVSQE 335

Query: 1053 QEAAASLVTST-VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCET 1111
              A+ S+  ST      G+       P   T  +    T TT   +     G        
Sbjct: 336  STASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPV 395

Query: 1112 HETGTTNTATTAMSSVGANHQ------------RDARRACAAGTPAVIRISVATGALEAA 1159
            H + T +  TT   S    H+            +D   A +  T A +++S         
Sbjct: 396  H-SSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLST------TY 448

Query: 1160 QGSKSQCQTRQTSATSTTMTVMATGAPCSAGPL---LGPSMAREPGG----------RSP 1206
              S S   T   SA+STT+       P  + P+     P  AR              RSP
Sbjct: 449  HSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSP 508

Query: 1207 AFVQLAPLSSKVRLSSPSIKDLP-AGRHSHAVSTAAMT---------RSSVGAGEPRMAP 1256
               Q          S  S +     G  +H  S+   T          SS+G+ E     
Sbjct: 509  GSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFR 568

Query: 1257 VCESLQGGSPST--------TVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTS 1308
               ++ G S  +         +  T L A   PS  V     +P        T    +T+
Sbjct: 569  DSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTT 628

Query: 1309 NAGSAQR---VCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTST 1365
              G +++     S+P        TTH   + TS+G + +          RP  TH T   
Sbjct: 629  KPGLSEKSTTFYSSP----RSPDTTHLPASMTSSGVSEESTTSH----SRPGSTHTTAFP 680

Query: 1366 GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425
            G+T   ++  L  ++T+SH               +P      L+P  T      P   T 
Sbjct: 681  GST---TMPGLSQESTASHS--------------SPGPTDTTLSPGSTTASSLGPEYTTF 723

Query: 1426 ETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVT 1485
             +    T TT+          P   +  G +E++     +  S     +   ST  +  +
Sbjct: 724  HSRPGSTETTLL---------PDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGES 774

Query: 1486 TVTQSTPVPGPSVPPP--------EELQVSPGPRQQLPPRQL-LQSASTALMGESAEVLS 1536
            T   S P    + P P        E    S G    +P   +  +S ++ L+ ES    S
Sbjct: 775  TTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHS 834

Query: 1537 ---ASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMA 1593
               ++QT   P +   S  GE S+   S+ +  +++     P  T + V++ +      +
Sbjct: 835  SPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA----PSTTSALVEEPTSYHS--S 888

Query: 1594 EAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPM 1653
                 TT    +  T      + A+ ++  A  T    A +  +VL         +   M
Sbjct: 889  PGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM 948

Query: 1654 DTSEAAATVTQAELGHLSA---EGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHH 1710
            +T+    + T   L   S          ATT+          A      + E     +  
Sbjct: 949  ETTALPGSTTTPGLSERSTTFHSSPRSPATTLS--------PASTTSSGVSEESTTSRSR 1000

Query: 1711 HLPTEALAPADSLNDPAIESNCLNELAGTVPSTVALLPSTATES 1754
               T   A  DS   P +  +     +    +   LLP++ T S
Sbjct: 1001 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 1044


>gi|239757995 PREDICTED: similar to hCG1747327, partial [Homo sapiens]
          Length = 1064

 Score =  126 bits (316), Expect = 2e-28
 Identities = 234/1098 (21%), Positives = 421/1098 (38%), Gaps = 177/1098 (16%)

Query: 515  TVTSLPAGVRMVVPTQSAQGTVIGSSPQM-------SGMAALAAAAAATQKIPPSSAPTV 567
            T+++  +   +  P   A  T + +SP          G+  LA+ A   ++  P    T+
Sbjct: 18   TLSTATSTSHVTFPRAEATRTALSNSPHSRYLAEWPQGVPQLASPAPGHRENAPM---TL 74

Query: 568  LSVPAGTTIVKTMA---VTPGTTTLPAT---VKVASSP-------------------VMV 602
             + P  T I +T+    V+  T+T P +    KV ++P                   + +
Sbjct: 75   TTSPHDTLISETLLSSLVSSNTSTTPTSKFAFKVETTPPTVLVYLATTECVYPTSFIITI 134

Query: 603  SNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTIT 662
            S+P T +  T      TS  + T  + +P+ TV ++  +T  ++    T+ +     T T
Sbjct: 135  SHP-TSICVTTTQVTFTSSYTPTPVTQKPVTTVTRTYPMTTTEKG---TSAMISSPSTTT 190

Query: 663  LVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTIL 722
              ++PI     S+ +S             + ++  T + +  P   I  T  P P  T L
Sbjct: 191  ARETPIVTVTPSSSVSATDTTFHTT----ISSTTRTTERTPLPTGSIHTTMSPTPVFTTL 246

Query: 723  KLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG 782
            K   ++    T+ IT+T             ++S++ +T++P  T  + ++ MS I++   
Sbjct: 247  KTAVTSTSPITSTITSTNT-----------VTSMTTTTSRPTATNTLSSL-MSNILS--- 291

Query: 783  ATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQP 842
                 S+P    P T +TT   T+ T   + ++T +P                       
Sbjct: 292  -----STP---VPSTEMTTS-HTTDTNPLSTLVTTLPT---------------------- 320

Query: 843  GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHST 902
             TI R+         TP + +    + T+ V   TT +T    +TGT+S +       S+
Sbjct: 321  -TITRS---------TPTSETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSS 370

Query: 903  SASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTL 962
              +  TP+T    + T +++  + +++  S++    T +   +T  I+  P +  T VT 
Sbjct: 371  QQTTETPMTPTTKLVTTTTETTSQSSLNFSSSAIYSTVS--TSTTAISSLPPTSGTMVTS 428

Query: 963  ITAPSGVEAQP------VHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNP 1016
                   + +P      VHD  +    +P   Q   T + A S      P T TL C+N 
Sbjct: 429  TNIVPTADLKPELILLEVHDQRIQ-AKNPRYSQTPFTSSTATS------PETTTLTCTN- 480

Query: 1017 PCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCS 1076
               T    T  T+TT V++ +   P+ T          A+    T+T+     S++    
Sbjct: 481  DISTESLTTAMTSTTPVISAI--TPKTTVTSMT---TTASGPTTTNTLSSLTSSILSSTP 535

Query: 1077 NPPCE--THETGTTNTATTATSNMAGQHGCSNPPCE-THETGTTNTATTAMSSVGANHQR 1133
             P  E  T  T TT   +T  + +      S P  E T+    T T T +M+ +  +   
Sbjct: 536  APNTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTDSMTEITYSTSM 595

Query: 1134 DARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLL 1193
                + A   P     S +   +E A    +      T  TS +     + A  S   + 
Sbjct: 596  TGTWSTATTLPLT---SCSLPTIETATTPTTNLGNTTTETTSHSTPSFTSSAIYSTVNIS 652

Query: 1194 GPSMAREP--GGRSPAFVQLAPLSSKVRLSSPSIKDL------PAGRHSHAVS-TAAMTR 1244
              +++  P   G    F  + P S    +S+ ++K++        G  + A   T+  T 
Sbjct: 653  TTTISSFPPSSGTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTSTFTV 712

Query: 1245 SSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCS-NPPCETHETGTTN 1303
            SS  A    + P   S+Q    ST V+ T   +   P+  +T   + N P     T +  
Sbjct: 713  SSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTS---PTERMTLTSTENTPTSYILTTSPV 769

Query: 1304 TATTSNAGSAQ-------RVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRP 1356
            T + S + SA           S+ P  T    TT  +T A +   +       +PP+   
Sbjct: 770  TYSFSPSMSASSDWTTDTESISSAPAITSTLHTTAESTLAPTTTNSFTTSANMEPPS--- 826

Query: 1357 CETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRV 1416
                 TT TG +   S  A   + T+   T +   E    P ++    T + +    +  
Sbjct: 827  -TAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFMTPMIST---TPITSSMTLRNT 882

Query: 1417 CSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV 1476
             ++         TT+T +++TS++ S+   P          ST+     ITS +  TT+ 
Sbjct: 883  MTSMTTAASRPTTTNTLSSLTSSILSSTPVP----------STE----VITSQTTNTTSP 928

Query: 1477 SSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGE-SAEV- 1534
            S+ +T   TT+T STP          E   S  P   +       + ST++ G  S E+ 
Sbjct: 929  STLVTTLPTTITTSTPT--------SETTYSTSPTSTVTDSTTETTYSTSITGTLSTEIS 980

Query: 1535 LSASQTPELPAAVDLSST 1552
            L A+ +  +   + ++ST
Sbjct: 981  LPATTSSLITKGISMTST 998



 Score =  119 bits (298), Expect = 3e-26
 Identities = 226/1046 (21%), Positives = 363/1046 (34%), Gaps = 154/1046 (14%)

Query: 408  TATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPT- 466
            T+T+PT      V   PP      A    V P + + IT+   + P     TT QV  T 
Sbjct: 96   TSTTPTSKFAFKVETTPPTVLVYLATTECVYPTSFI-ITI---SHPTSICVTTTQVTFTS 151

Query: 467  ----VPGSSISVPTAARTQGVPAVLK-----VTGPQATTG--TPLVTMRPASQAGKAPVT 515
                 P +   V T  RT  +    K     ++ P  TT   TP+VT+ P+S       T
Sbjct: 152  SYTPTPVTQKPVTTVTRTYPMTTTEKGTSAMISSPSTTTARETPIVTVTPSSSVSATDTT 211

Query: 516  V-TSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPP--------SSAPT 566
              T++ +  R    T    G++  +         L  A  +T  I          +S  T
Sbjct: 212  FHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTT 271

Query: 567  VLSVPAGT-TIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKT------------- 612
              S P  T T+   M+    +T +P+T ++ +S    +NP + ++ T             
Sbjct: 272  TTSRPTATNTLSSLMSNILSSTPVPST-EMTTSHTTDTNPLSTLVTTLPTTITRSTPTSE 330

Query: 613  ---AAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS 669
                A+   T   S T  +   ++T   S T T+   +    T    +T T  LV +   
Sbjct: 331  TTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSSQQTTETPMTPTTKLVTTTTE 390

Query: 670  VPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSAD 729
                S+L  +   + S V T            ST  ++ +  T G +   T   +V +AD
Sbjct: 391  TTSQSSLNFSSSAIYSTVST------------STTAISSLPPTSGTMVTST--NIVPTAD 436

Query: 730  GKPTTIITTTQASGAGTK-PTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTS 788
             KP  I+          K P        S + T P TTT+  T   + I T++  T +TS
Sbjct: 437  LKPELILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCT---NDISTESLTTAMTS 493

Query: 789  SPGIKSPITIITTKV-MTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTIL- 846
            +  + S IT  TT   MT+    P           T +    +T  +L   P     ++ 
Sbjct: 494  TTPVISAITPKTTVTSMTTTASGP----------TTTNTLSSLTSSILSSTPAPNTEVIT 543

Query: 847  ----RTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHST 902
                 T P   +    P  ++   P   T      TG  T      T STS+ G    +T
Sbjct: 544  SHTTTTTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTDSMTEITYSTSMTGTWSTAT 603

Query: 903  SASLAT-PITTLGTIATLSSQVINPTAITVSAAQTTLTAAG-----GLTTPTITMQPVSQ 956
            +  L +  + T+ T  T ++ + N T  T S +  + T++       ++T TI+  P S 
Sbjct: 604  TLPLTSCSLPTIETATTPTTNLGNTTTETTSHSTPSFTSSAIYSTVNISTTTISSFPPSS 663

Query: 957  PTQVTLITAPSGVEAQPVHDLPVSILASPTTEQP---------TATVTIADSGQGDVQPG 1007
             T VT  T      +  +    +  +  P+             T+T T++ S        
Sbjct: 664  GTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTSTFTVSSS-----SAM 718

Query: 1008 TVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQ 1067
            + ++  S P  +  E  T  + TTT          PT+   +   +    S + +T    
Sbjct: 719  STSVTPSAPSIQNKEISTLVSTTTTT--------SPTERMTLTSTENTPTSYILTT---- 766

Query: 1068 NGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSV 1127
              S V    +P        TT+T              S+ P  T    TT  +T A    
Sbjct: 767  --SPVTYSFSPSMSASSDWTTDT-----------ESISSAPAITSTLHTTAESTLA---- 809

Query: 1128 GANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPC 1187
                            P        +  +E    + +   T Q++ TS+T T + T    
Sbjct: 810  ----------------PTTTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLET---- 849

Query: 1188 SAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSV 1247
                 L P+            +   P++S + L +       A       +T +   SS+
Sbjct: 850  ---TTLTPTTDISTESFMTPMISTTPITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSI 906

Query: 1248 GAGEPRMAP---VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNT 1304
             +  P  +      ++    SPST VT            + T   ++P     ++ T  T
Sbjct: 907  LSSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTSTVTDSTTETT 966

Query: 1305 ATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTS 1364
             +TS  G+     S  P  T    T   + T+T N  T   E             H T S
Sbjct: 967  YSTSITGTLSTEIS-LPATTSSLITKGISMTSTRNLVTTTNENTSHSTPTFTLTIHSTIS 1025

Query: 1365 TGTTMSVSVGALL-PDATSSHRTVES 1389
            T TT   SV     P  TS+  T  S
Sbjct: 1026 TSTTAISSVPTTSGPIVTSTTMTPSS 1051



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 149/641 (23%), Positives = 257/641 (40%), Gaps = 98/641 (15%)

Query: 403  PATAATATSPTPNPVPSVPANPPKS--PAPAAAAPAVQPLT-QVGITLLPQAAPAPPTTT 459
            P T++TATSP    +        +S   A  +  P +  +T +  +T +   A  P TT 
Sbjct: 462  PFTSSTATSPETTTLTCTNDISTESLTTAMTSTTPVISAITPKTTVTSMTTTASGPTTTN 521

Query: 460  TIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSL 519
            T+  L +   S +S   A  T+ + +    T P +T    LVT  P + A   P + T+ 
Sbjct: 522  TLSSLTS---SILSSTPAPNTEVITSHTTTTTPPST----LVTTLPTAIARSTPTSETTY 574

Query: 520  PAGVRMVVPTQSAQGTVIGSSPQMSGMAALAA--AAAATQKIPPSSAPTVLSVPA----- 572
            P     + PT    GTV  S  +++   ++    + A T  +   S PT+ +        
Sbjct: 575  P-----ISPT----GTVTDSMTEITYSTSMTGTWSTATTLPLTSCSLPTIETATTPTTNL 625

Query: 573  -GTTIVKTMAVTPGTTT--LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTST 629
              TT   T   TP  T+  + +TV ++++ +    P++  + T      +S+S+  +T+T
Sbjct: 626  GNTTTETTSHSTPSFTSSAIYSTVNISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTTT 685

Query: 630  RPIIT---VHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSV 686
               IT   V  +G +T A       TV      + ++  S  S+      IS L  V + 
Sbjct: 686  LKNITQPSVGSTGFLTAATDLTSTFTVSSSSAMSTSVTPSAPSIQNKE--ISTL--VSTT 741

Query: 687  VQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAG------------TILKLVTSADGKPTT 734
              T P +   +T   +T   T  I T  P+               T  + ++SA    +T
Sbjct: 742  TTTSPTERMTLTSTENTP--TSYILTTSPVTYSFSPSMSASSDWTTDTESISSAPAITST 799

Query: 735  IITTTQASGAGTKP-------------TILGISSVSPSTTKPGTTTIIKTI---PMSAII 778
            + TT +++ A T               T +  +    ST    T T ++T    P + I 
Sbjct: 800  LHTTAESTLAPTTTNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDIS 859

Query: 779  TQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGA 838
            T++  T + S+  I S +T+  T  MTS T       TA  +  T +    +T  +L   
Sbjct: 860  TESFMTPMISTTPITSSMTLRNT--MTSMT-------TAASRPTTTNTLSSLTSSILSST 910

Query: 839  P--------------GQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLG 884
            P                P T++ T+P   +   TP + +    + T+ V   TT  T   
Sbjct: 911  PVPSTEVITSQTTNTTSPSTLVTTLPTT-ITTSTPTSETTYSTSPTSTVTDSTTETTYST 969

Query: 885  TVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGL 944
            ++TGT+ST ++     +T++SL T     G   T +  ++  T    S +  T T     
Sbjct: 970  SITGTLSTEISLP---ATTSSLITK----GISMTSTRNLVTTTNENTSHSTPTFTLTIHS 1022

Query: 945  TTPTITMQPVSQP-TQVTLITAPSGVEAQPVHDLPVSILAS 984
            T  T T    S P T   ++T+ +   +    D+P + L +
Sbjct: 1023 TISTSTTAISSVPTTSGPIVTSTTMTPSSLTADIPTTTLTT 1063



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 91/481 (18%), Positives = 177/481 (36%), Gaps = 73/481 (15%)

Query: 401  DIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTT 460
            +I  T  ++  P+   + +     P S +   +   ++ +TQ  +        A   T+T
Sbjct: 650  NISTTTISSFPPSSGTMVTFTTMNPSSLSTDISTTTLKNITQPSVGSTGFLTAATDLTST 709

Query: 461  IQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLP 520
              V  +   S+   P+A   Q       V+    T+ T  +T+        + +  TS  
Sbjct: 710  FTVSSSSAMSTSVTPSAPSIQNKEISTLVSTTTTTSPTERMTLTSTENTPTSYILTTS-- 767

Query: 521  AGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580
                               SP MS     A++   T     SSAP + S         T+
Sbjct: 768  -------------PVTYSFSPSMS-----ASSDWTTDTESISSAPAITS---------TL 800

Query: 581  AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGT 640
              T  +T  P T    ++   +  P+     TA A  GT  S+ T+++   + T   + T
Sbjct: 801  HTTAESTLAPTTTNSFTTSANMEPPS-----TAVATTGTGQSTFTSSTATFLETTTLTPT 855

Query: 641  VTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ 700
              ++ ++ +          T  +  +PI+    S  + N    M+   ++P  T+ ++  
Sbjct: 856  TDISTESFM----------TPMISTTPIT---SSMTLRNTMTSMTTAASRPTTTNTLSS- 901

Query: 701  ASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPST 760
                 +T  I +  P+P+  ++   T+    P+T++TT   +   + PT     S SP++
Sbjct: 902  -----LTSSILSSTPVPSTEVITSQTTNTTSPSTLVTTLPTTITTSTPTSETTYSTSPTS 956

Query: 761  TKPGTTT-------IIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAK 813
            T   +TT       I  T+     +    ++ +T    + S   ++TT    +    P  
Sbjct: 957  TVTDSTTETTYSTSITGTLSTEISLPATTSSLITKGISMTSTRNLVTTTNENTSHSTPTF 1016

Query: 814  IITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLV 873
             +T    I+T       +   +   P   G I+ +  M      TP +++A  P  T   
Sbjct: 1017 TLTIHSTIST-------STTAISSVPTTSGPIVTSTTM------TPSSLTADIPTTTLTT 1063

Query: 874  V 874
            +
Sbjct: 1064 I 1064



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 78/408 (19%), Positives = 141/408 (34%), Gaps = 60/408 (14%)

Query: 400  YDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLP---QAAPAPP 456
            + + +++A +TS TP+             AP+     +  L     T  P       +  
Sbjct: 710  FTVSSSSAMSTSVTPS-------------APSIQNKEISTLVSTTTTTSPTERMTLTSTE 756

Query: 457  TTTTIQVLPTVPGS-SISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVT 515
             T T  +L T P + S S   +A +        ++   A T T    +   +++  AP T
Sbjct: 757  NTPTSYILTTSPVTYSFSPSMSASSDWTTDTESISSAPAITST----LHTTAESTLAPTT 812

Query: 516  VTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTT 575
              S      M  P+ +   T  G S   S  A        T     S+   +  + + T 
Sbjct: 813  TNSFTTSANMEPPSTAVATTGTGQSTFTSSTATFLETTTLTPTTDISTESFMTPMISTTP 872

Query: 576  IVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITV 635
            I  +M +    T++       ++   +S+  + +L +        ++S T  +T P   V
Sbjct: 873  ITSSMTLRNTMTSMTTAASRPTTTNTLSSLTSSILSSTPVPSTEVITSQTTNTTSPSTLV 932

Query: 636  HKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTS 695
                T          TT     T T+                                T 
Sbjct: 933  TTLPTTITTSTPTSETTYSTSPTSTV--------------------------------TD 960

Query: 696  AVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTT--IITTTQASGAGTKPTILGI 753
            + T    +  +T  + T+  LPA T   L+T      +T  ++TTT  + + + PT    
Sbjct: 961  STTETTYSTSITGTLSTEISLPA-TTSSLITKGISMTSTRNLVTTTNENTSHSTPTF--- 1016

Query: 754  SSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITT 801
             +++  +T   +TT I ++P ++       T   SS     P T +TT
Sbjct: 1017 -TLTIHSTISTSTTAISSVPTTSGPIVTSTTMTPSSLTADIPTTTLTT 1063



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 100/520 (19%), Positives = 178/520 (34%), Gaps = 52/520 (10%)

Query: 1301 TTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETH 1360
            ++NT+TT  +  A +V + PP     T   + ATT               P +     +H
Sbjct: 93   SSNTSTTPTSKFAFKVETTPP-----TVLVYLATTECV-----------YPTSFIITISH 136

Query: 1361 QTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFP-------T 1413
             T+   TT  V+  +       + + V +       P  T + GT+ +   P       T
Sbjct: 137  PTSICVTTTQVTFTSSYTPTPVTQKPVTT--VTRTYPMTTTEKGTSAMISSPSTTTARET 194

Query: 1414 QRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSV---NITSSS 1470
              V   P      T TT   T  ++  ++ + P P  S    +  T   +     +TS+S
Sbjct: 195  PIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTTMSPTPVFTTLKTAVTSTS 254

Query: 1471 AITTTVSST--LTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALM 1528
             IT+T++ST  +T   TT ++ T     S      L  +P P  ++       +   + +
Sbjct: 255  PITSTITSTNTVTSMTTTTSRPTATNTLSSLMSNILSSTPVPSTEMTTSHTTDTNPLSTL 314

Query: 1529 GESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPP---PPTQSEVDQL 1585
              +        TP        S T   +        + V T  + P    PPT S     
Sbjct: 315  VTTLPTTITRSTPTSETTYPASPTSTVTDSTTEITYSTVLTGTLSPTTTLPPTSSS---- 370

Query: 1586 SLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQA 1645
               Q+        TT L+ T  T E  + ++   +++   +T      AI ++   +   
Sbjct: 371  ---QQTTETPMTPTTKLVTT--TTETTSQSSLNFSSSAIYSTVSTSTTAISSLPPTSGTM 425

Query: 1646 VMGTGEPMDTSEAAATVTQAELGHLSAEGQEGQATTIPI---VLTQQELAALVQQQQLQ- 1701
            V  T   + T++    +   E+     + +  + +  P      T  E   L     +  
Sbjct: 426  VTST-NIVPTADLKPELILLEVHDQRIQAKNPRYSQTPFTSSTATSPETTTLTCTNDIST 484

Query: 1702 EAQAQQQHHHLPT-EALAP---ADSLNDPAIESNCLNELAGTVPSTVALLPSTATESLAP 1757
            E+         P   A+ P     S+   A      N L+    S ++  P+  TE +  
Sbjct: 485  ESLTTAMTSTTPVISAITPKTTVTSMTTTASGPTTTNTLSSLTSSILSSTPAPNTEVITS 544

Query: 1758 SNTFVAPQPVVVAS-PAKLQAAATLTEVANGIESLGVKPD 1796
              T   P   +V + P  +  +   +E    I   G   D
Sbjct: 545  HTTTTTPPSTLVTTLPTAIARSTPTSETTYPISPTGTVTD 584


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score =  119 bits (297), Expect = 4e-26
 Identities = 278/1192 (23%), Positives = 421/1192 (35%), Gaps = 206/1192 (17%)

Query: 512  APVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVL--- 568
            A +  TS  + +     T     + I    + S  +  +  A AT  +P  S P+VL   
Sbjct: 35   AALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGD 94

Query: 569  --SVPAGTTIVKTMAVTPGTTTLPATVKVA----SSPVMVSNPATRMLKTAAAQVGTSVS 622
                P  +  ++T A+ PG+TT P   + +    SSP    +P T  L  +    G S  
Sbjct: 95   STPSPISSGSMETTAL-PGSTTKPGLSEKSTTFYSSP---RSPDTTHLPASMTSSGVSEE 150

Query: 623  SATNTSTRP--IITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNL 680
            S T+ S RP    T    G+ T+   +Q  T        T T + SP     GS   S+L
Sbjct: 151  STTSHS-RPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTL-SP-----GSTTASSL 203

Query: 681  GKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL------------PAGTILKLVTSA 728
            G   +   ++P  T       +T   + +++   P+            PAG+     T+ 
Sbjct: 204  GPEYTTFHSRPGSTETTLLPDNT-TASGLLEASMPVHSSTRSPHTTLSPAGS-----TTR 257

Query: 729  DGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAG----AT 784
             G+ TT  +   +      P     + V PSTT  G+ + I T  +SA  T +G    +T
Sbjct: 258  QGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEEST 317

Query: 785  GVTSSPGIKSPITIITTKVMTSGTG----------------APAKIITAVPKIATGHGQQ 828
               SSPG    +    +   TSG G                AP+     V +  + H   
Sbjct: 318  TYHSSPGSTQTMHFPESDT-TSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP 376

Query: 829  GVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTT---LVVKGTTGVTTLGT 885
            G T       P    T  R+            T + V PA +T   L+ + TT   + G+
Sbjct: 377  GSTATT--HFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 434

Query: 886  VTGTV---STSLAGAGGHSTS--ASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTA 940
            +  T    ST+  G    ST+  +S  +P TTL   +T SS V   +  + S   +T T 
Sbjct: 435  METTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTT 494

Query: 941  AGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSG 1000
            A     P  T  P       T  ++P   +      LP S   S  +++ T + + + S 
Sbjct: 495  A----FPDSTTTPGLSRHSTTSHSSPGSTDTTL---LPASTTTSGPSQESTTSHSSSGST 547

Query: 1001 QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLV 1060
               + PG+ T +       T  +   +T TT         P  T    + +    A++ V
Sbjct: 548  DTALSPGSTTALSFGQESTTFHSNPGSTHTTL-------FPDSTTSSGIVE----ASTRV 596

Query: 1061 TSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHET-----G 1115
             S+ G    ++    S  P    E+    T   +T         +  P E   T     G
Sbjct: 597  HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG 656

Query: 1116 TTNTATTAMSSVGANHQRDA----RRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQT 1171
            +T T     SS  + H   +        A+GT      S  +G        + +  T + 
Sbjct: 657  STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSG--------RGESTTSRI 708

Query: 1172 SATSTTMTVMATGAPCSAGPLLGPSMAREPG-GRSPAFVQLAPLSSKVRLSSPSIKDLPA 1230
            S  ST +T +             P     PG   +      +P S    LS  S+  L  
Sbjct: 709  SPGSTEITTL-------------PGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGV 755

Query: 1231 GRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVT----ALEALLCPSATVT 1286
            G  S        +RS  G+    ++P   +  G S  +T   +    + E  + P +T T
Sbjct: 756  GEES------TTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTT 809

Query: 1287 QV-------CSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTA--- 1336
             V         + P  TH T  T  +TTS            P  T +TG   T TTA   
Sbjct: 810  SVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPAST-QTGLPATLTTADLG 868

Query: 1337 -------TSNGGTGQP-----------EGGQQPPAGRPCETHQTTSTG--TTMSVS---- 1372
                   +S+G TG              G   P    P  T  TT  G  TT S+S    
Sbjct: 869  EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKST 928

Query: 1373 ---VGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFP---TQRVCSNPPCETHE 1426
                    PDAT S  T  S      + +   Q G+     FP   T    S  P  +H 
Sbjct: 929  TFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHS 988

Query: 1427 T-GTTHTATTVTSNMSSN--QDPPPAASDQGEVESTQGDSVNITSS--SAITTTVSS--- 1478
            + G+T    +  S  +S+  Q      S  G+ E+T      ITS    A T T SS   
Sbjct: 989  SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGS 1048

Query: 1479 ---TLTRAVTT----------------VTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQL 1519
               TLT A +T                 + +TP P  +   P E+  +   R    P   
Sbjct: 1049 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1108

Query: 1520 LQSASTALMGESAEVLSASQTPELPAAVDLSS-------TGEPSSGQESAGS 1564
              ++ST L G S E  +   +P         +        GEP++   S+GS
Sbjct: 1109 FSASSTTL-GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGS 1159



 Score =  117 bits (293), Expect = 1e-25
 Identities = 283/1292 (21%), Positives = 472/1292 (36%), Gaps = 178/1292 (13%)

Query: 405  TAATATSPTPNPVPSVPANPPKSPAPAAAAPAV-QPLTQVGITLLPQAAPAPPTTTTIQV 463
            T A+       PV S   +P  + +PA +     +  T           PAPPTTT+  V
Sbjct: 226  TTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFV 285

Query: 464  LP--TVPGSSISVPT---AARTQGVPAVLKVTGPQATTGTPLVTMRPASQA--------- 509
             P  T  GS  S+PT   +AR+     V + T   ++ G+      P S           
Sbjct: 286  EPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEEST 345

Query: 510  ---GKAPVTVTSLPAGVRMVV--PTQ------SAQGTVIGSSPQMSGMAALAAAAAATQK 558
                    T++S P+    +V  PT       S   T    S   SG +  + A+ ++Q 
Sbjct: 346  TSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQD 405

Query: 559  ------IPPSSAPTVL-----SVPAGTTIVKTMAVTPGTTTLPA----TVKVASSPVMVS 603
                  +P  S  +VL     + P  +  ++T A+ PG+TT P     +    SSP    
Sbjct: 406  ATGTIVLPARSTTSVLLGESTTSPISSGSMETTAL-PGSTTTPGLSERSTTFHSSP---R 461

Query: 604  NPATRMLKTAAAQVGTSVSSATNT----STRPIITVHKSGTVTVAQQAQVVTTVVGGVTK 659
            +PAT +   +    G S  S T+     ST        + T  +++ +    +  G    
Sbjct: 462  SPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 521

Query: 660  TITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVT-GQASTGPVTQIIQTKGPL-P 717
            T+    +  S P   +  S+     +     P  T+A++ GQ ST   +    T   L P
Sbjct: 522  TLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFP 581

Query: 718  AGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAI 777
              T    +  A        T   +S    + T+   SS SP     G +T  +T P S  
Sbjct: 582  DSTTSSGIVEAS-------TRVHSSTGSPRTTLSPASSTSPGL--QGESTAFQTHPASTH 632

Query: 778  ITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKG 837
             T +  +  T++  ++   T   +   T  T  PA   T      +GH ++     +   
Sbjct: 633  TTPSPPS--TATAPVEESTTYHRSPGSTPTTHFPASSTT------SGHSEK---STIFHS 681

Query: 838  APGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGA 897
            +P   GT   +            T S    + T+ +  G+T +TTL   T T   S A  
Sbjct: 682  SPDASGTTPSSAHS---------TTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAST 732

Query: 898  GGHSTSASLATPITT-------LGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTIT 950
              +S+  S  T ++        +G  +T S      T  TVS A TT       +T   +
Sbjct: 733  TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS 792

Query: 951  MQPVSQPTQV---TLITAPSGVEAQPVHDLPVSI---------LASPTTEQPTATVTIAD 998
                S  T V   +  T+  G E    H  P S            S  TE+ TA      
Sbjct: 793  SSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 852

Query: 999  SGQGDVQPGTVTLV-----CSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQ-FVCDR 1052
            S Q  + P T+T        +  P  +  TGT  +   +  + L G   P+++     + 
Sbjct: 853  STQTGL-PATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 911

Query: 1053 QEAAASLVTSTVGQQNGSVVRVCSNP-----PCETHETGTTNTATTATSNMAGQHGCSNP 1107
                 S  T ++ +++ +      +P     P  T  +G +  ++T+ S     H  + P
Sbjct: 912  TTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP 971

Query: 1108 -----------PCETHET-----GTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
                       P  +H +      T +  +T  SS+G              T  +   ++
Sbjct: 972  DSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTI 1031

Query: 1152 ATGALEAA---QGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAF 1208
             +G +EA+     S     T  T A+ST+  +        + P         P G + A 
Sbjct: 1032 TSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP-SSSDTTPSPPGTTAAP 1090

Query: 1209 VQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV--CESLQGGSP 1266
            V+++        S+P+     +         +    SS GA    + P     S+  G P
Sbjct: 1091 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 1150

Query: 1267 STT-VTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETH 1325
            +T+ ++  + E    P +T T   S      + +  +   T S A +     S     +H
Sbjct: 1151 TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1210

Query: 1326 -ETGTTHTATTATSNGGTGQPEGGQQPPAGR--PCETHQTTSTGTTMSVSVGALLPDATS 1382
               G+THT       G T  P   Q+  A    P  T  T S G+T + S+G   P++T+
Sbjct: 1211 SRPGSTHTTAFP---GSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG---PESTT 1264

Query: 1383 SHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTT--HTATTVTSNM 1440
             H +  S  E    P  T  +G  L A  P      +P       G+T     +T   + 
Sbjct: 1265 FHSSPGS-TETTLLPDNTTASG-LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1322

Query: 1441 SSNQD----PPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA-VTTVTQSTPVPG 1495
             S++D    PP   S   E+ +T   S + T ++  + + S+TL R+  +T   S+PV  
Sbjct: 1323 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS-STTLGRSEESTTVHSSPVAT 1381

Query: 1496 PSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLS---ASQTPELPAAVDLSST 1552
             + P P                   +S ++ L+ ES    S   ++QT   P +   S  
Sbjct: 1382 ATTPSP------------------ARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGR 1423

Query: 1553 GEPSSGQESAGSAVVATVVVQPPPPTQSEVDQ 1584
             E S    S+ +  +++    PP  T + V++
Sbjct: 1424 SEESRTSHSSTTHTISS----PPSTTSALVEE 1451



 Score = 94.4 bits (233), Expect = 1e-18
 Identities = 278/1258 (22%), Positives = 433/1258 (34%), Gaps = 194/1258 (15%)

Query: 427  SPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAV 486
            S AP+  +  V+  T         ++P    TT      T  G S     +  +Q     
Sbjct: 356  SSAPSTTSALVEEPTSY------HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT 409

Query: 487  LKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGM 546
            + +  P  +T + L+     S      +  T+LP       P  S + T   SSP+    
Sbjct: 410  IVL--PARSTTSVLLGESTTSPISSGSMETTALPGST--TTPGLSERSTTFHSSPRSP-- 463

Query: 547  AALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPA 606
            A   + A+ T       + T  S P  T    T A    TTT   +    +S     +  
Sbjct: 464  ATTLSPASTTSSGVSEESTTSRSRPGST---HTTAFPDSTTTPGLSRHSTTSHSSPGSTD 520

Query: 607  TRMLKTAAAQVGTSVSSATN-TSTRPIITVHKSGTVTVAQQAQVVTT------------- 652
            T +L  +    G S  S T+ +S+    T    G+ T     Q  TT             
Sbjct: 521  TTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLF 580

Query: 653  ----VVGGVTKTITLVKSPISVPG-----GSALISNLGKVMSVVQTKPVQTSAVTGQAST 703
                   G+ +  T V S    P       S+    L    +  QT P  T       ST
Sbjct: 581  PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPST 640

Query: 704  G--PV---TQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSP 758
               PV   T   ++ G  P        T++     + I  +    +GT P     SS   
Sbjct: 641  ATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTP-----SSAHS 695

Query: 759  STTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818
            +T+  G +T  +  P S  IT     G T++PG+    T        S   +P   ++  
Sbjct: 696  TTSGRGESTTSRISPGSTEITTL--PGSTTTPGLSEAST-----TFYSSPRSPTTTLSPA 748

Query: 819  PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPV-------TVSAVKPAVTT 871
               + G G++  T     G+     +   T   G     T V       T + V P  TT
Sbjct: 749  SMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTT 808

Query: 872  LVVKG--------------TTGVTTLGTVTGTVSTSLAGAGGH-STSASLATPITT--LG 914
              V G              TT  T   T +G    S A  G   ST   L   +TT  LG
Sbjct: 809  TSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG 868

Query: 915  TIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPV 974
              +T        T   +S A++T +   G +TP+        P+     T P       +
Sbjct: 869  EESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRL-----SPSSTETTTLPGSPTTPSL 923

Query: 975  HDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVV 1034
             +   +   SP +  P AT++ A +    V   + T    + P  TH T   ++ TT+ +
Sbjct: 924  SEKSTTFYTSPRS--PDATLSPATTTSSGVSEESST--SHSQPGSTHTTAFPDSTTTSDL 979

Query: 1035 ANLGGHPQPTQVQFVCDRQEAA---ASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTA 1091
            +      +PT         EA     S   S++GQQ+             T  +   +T 
Sbjct: 980  SQ-----EPTTSHSSQGSTEATLSPGSTTASSLGQQS------------TTFHSSPGDTE 1022

Query: 1092 TTATSNMAGQHGCSNPPCETHE-TGTTNTATTAMSSVGANHQRDARR-----ACAAGTPA 1145
            TT   +     G       TH  TG+ +T  T  SS  A  Q ++       + +  TP+
Sbjct: 1023 TTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS 1082

Query: 1146 VIRISVATGALEAAQGSK-SQCQTRQTSATSTTM-----TVMATGAPCSAGPLLGPS--- 1196
                + A   +     S+ S   T   SA+STT+     +     +P + G  L P+   
Sbjct: 1083 PPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSA 1142

Query: 1197 ---MAREP------GGRS-----PAFVQLAPLSSKVRL--SSPSIKDL---PAGRHSHAV 1237
               +  EP       G +     P     A LS K     SSP   D    PA   S  V
Sbjct: 1143 TSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV 1202

Query: 1238 STAAMT-RSSVGAGEPRMAPVCESLQGGSPSTTVTVTA---LEALLCPSATVTQVCSNPP 1293
            S  + T  S  G+      P   ++ G S  +T + ++    +  L P +T T     P 
Sbjct: 1203 SEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGST-TASSLGPE 1261

Query: 1294 CETHETGTTNTATT---SNAGSAQRVCSNPPCETHETGTTHTATT-ATSNGGTGQPEGGQ 1349
              T  +   +T TT    N  ++  + ++ P  +  TG+ HT  + A S    G+    Q
Sbjct: 1262 STTFHSSPGSTETTLLPDNTTASGLLEASTPVHS-STGSPHTTLSPAGSTTRQGESTTFQ 1320

Query: 1350 QPPAGR------PCETH-----QTTSTGTTMSVSVGALLPDATSSHRTVES----GLEVA 1394
              P+ +      P  T       TTS G+  S         +T+  R+ ES       VA
Sbjct: 1321 SWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA 1380

Query: 1395 AAPSVTP-----------------QAGTALLAPFPTQRVCSNPPCE--THETGTTHTATT 1435
             A + +P                   G+     FP     S    E  T  + TTHT ++
Sbjct: 1381 TATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS 1440

Query: 1436 VTSNMSS-NQDPPPAASDQGEVESTQGDSVNITS--SSAITTTVSSTLTRAVTTVTQSTP 1492
              S  S+  ++P    S  G + +T     + TS  S   T + SS  T  +T +     
Sbjct: 1441 PPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFT 1500

Query: 1493 VPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLS 1550
              G  +       +SPG  +      L  +A+T  +   + +L  S     P    +S
Sbjct: 1501 TSG-RIAESTTFYISPGSME----TTLASTATTPGLSAKSTILYTSDLVGEPTTFYIS 1553



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 135/622 (21%), Positives = 226/622 (36%), Gaps = 78/622 (12%)

Query: 410  TSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPG 469
            +SP       +P +   S    A+ P       +  TL P ++ +           + P 
Sbjct: 1016 SSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPS 1075

Query: 470  SSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPT 529
            SS + P+   T   P  +  T     + TP      +S         T+L          
Sbjct: 1076 SSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASS---------TTL---------G 1117

Query: 530  QSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTL 589
            +S + T + SSP  +G A     +A +  +     PT   + +G+T  +T A+   TTT 
Sbjct: 1118 RSEESTTVHSSPGATGTALFPTRSATSVLV---GEPTTSPISSGST--ETTALPGSTTTA 1172

Query: 590  PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP--IITVHKSGTVTVAQQA 647
              + K  +      +P T +   +    G S  S T+ S RP    T    G+ T+   +
Sbjct: 1173 GLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS-RPGSTHTTAFPGSTTMPGVS 1231

Query: 648  QVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVT 707
            Q  T        T T + SP     GS   S+LG   +   + P  T       +T   +
Sbjct: 1232 QESTASHSSPGSTDTTL-SP-----GSTTASSLGPESTTFHSSPGSTETTLLPDNT-TAS 1284

Query: 708  QIIQTKGPL------------PAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISS 755
             +++   P+            PAG+     T+  G+ TT  +   +      P     + 
Sbjct: 1285 GLLEASTPVHSSTGSPHTTLSPAGS-----TTRQGESTTFQSWPSSKDTMPAPPTTTSAF 1339

Query: 756  VSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKII 815
            V  STT  G+ +   T   SA  T  G +        +   T+ ++ V T+ T +PA+  
Sbjct: 1340 VELSTTSHGSPSSTPTTHFSASSTTLGRS--------EESTTVHSSPVATATTPSPARST 1391

Query: 816  TA--VPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLV 873
            T+  V +    H   G TQ +    P       R+         T  T+S+     + LV
Sbjct: 1392 TSGLVEESTAYHSSPGSTQTM--HFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 1449

Query: 874  VKGTTGVTTLGTVTGTVSTSLAGAGGHS--TSASLATP----ITTLGTIATLSSQVINPT 927
             + T+  ++ G++  T     +   G S  ++AS ++P    IT L    T S ++   T
Sbjct: 1450 EEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAEST 1509

Query: 928  AITVSAAQTTLTAAGGLTTPTI--------TMQPVSQPTQVTLITAPSGVEAQPVHDLPV 979
               +S      T A   TTP +        T   V +PT   +  +P+     P      
Sbjct: 1510 TFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPTTFYISPSPTYTTLFPASSSTS 1569

Query: 980  SILASPTT--EQPTATVTIADS 999
             +    TT    P+ T TI  +
Sbjct: 1570 GLTEESTTFHTSPSFTSTIVST 1591



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 134/683 (19%), Positives = 222/683 (32%), Gaps = 101/683 (14%)

Query: 1296 THETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGR 1355
            T    TT+T +++ + +A    ++       T TTH   ++T +G + + +     P   
Sbjct: 18   TFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSP--- 74

Query: 1356 PCETHQTT--STGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAG--------- 1404
              +   TT    G+T SV VG   P   SS       +E  A P  T + G         
Sbjct: 75   --DAMATTVLPAGSTPSVLVGDSTPSPISS-----GSMETTALPGSTTKPGLSEKSTTFY 127

Query: 1405 --------TALLAPFPTQRVCSNPPCETHETGTTHTAT--TVTSNMSSNQDPPPAASDQG 1454
                    T L A   +  V           G+THT      T+    +Q+   + S  G
Sbjct: 128  SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPG 187

Query: 1455 EVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPGPRQQL 1514
              ++T   S   T++S++    ++  +R  +T T   P    +     E  +      + 
Sbjct: 188  PTDTTL--SPGSTTASSLGPEYTTFHSRPGSTETTLLP-DNTTASGLLEASMPVHSSTRS 244

Query: 1515 PPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTG--EPSSGQESAGSAVVATVVV 1572
            P   L  + ST   GES    S   + +   A   +++   EPS+    + S++  T + 
Sbjct: 245  PHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHI- 303

Query: 1573 QPPPPTQSEVDQLSLPQELMAEAQAGTTTLM------VTGLTPEELAVTAAAEAAAQAAA 1626
                  +S    L + +     +  G+T  M       T    EE   + ++     ++A
Sbjct: 304  ----SARSTTSGL-VEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 358

Query: 1627 TEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGHLSAEGQE---------- 1676
                 AL  +     +      T    D+S  +    ++   H S +             
Sbjct: 359  PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT 418

Query: 1677 ----GQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHH----LPTEALAPADSLNDPAI 1728
                G++TT PI     E  AL           +    H     P   L+PA + +    
Sbjct: 419  SVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVS 478

Query: 1729 ESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQP---VVVASPAKLQAAATLTEVA 1785
            E +  +        T A   ST T  L+  +T     P        PA    +    E  
Sbjct: 479  EESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 538

Query: 1786 NGIESLGVKPDLPPPPSKAPMK--KENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLG 1843
                S G       P S   +   +E+  F       +N   TH  L PD    S    G
Sbjct: 539  TSHSSSGSTDTALSPGSTTALSFGQESTTFH------SNPGSTHTTLFPDSTTSS----G 588

Query: 1844 TVPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSP 1903
             V    ++      P T                   +S   +  PG  G   A +    P
Sbjct: 589  IVEASTRVHSSTGSPRTT------------------LSPASSTSPGLQGESTAFQ--THP 628

Query: 1904 DGAHLTWEPPSVTSGKIIEYSVY 1926
               H T  PPS  +  + E + Y
Sbjct: 629  ASTHTTPSPPSTATAPVEESTTY 651


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  118 bits (296), Expect = 5e-26
 Identities = 318/1437 (22%), Positives = 489/1437 (34%), Gaps = 190/1437 (13%)

Query: 417  VPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPT 476
            +P +P+     PA  AA P V P    G              +TI  +   P  S++V T
Sbjct: 357  IPPLPSRNEVVPATVAAFPVVAPSVDKG-------------PSTISSITCSPSGSLNVAT 403

Query: 477  AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTV 536
            +       +++  + P AT   PLV   P S  G  P+ VT+ P  +    PT + +   
Sbjct: 404  SFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTN-PCTI-AAAPTTTFEVAT 461

Query: 537  IGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVA 596
              S P  SG  +     +    +    AP   S    TT+   + V+P     P  +K  
Sbjct: 462  CVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTL--RIPVSPPLPD-PEDLKNL 518

Query: 597  SSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGG 656
             S V+V  P  + L+T  A    S+  A  +  +  +T  K  TV    QA    +    
Sbjct: 519  PSSVLVKFPTQKDLQTVPA----SLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNS--PS 572

Query: 657  VTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL 716
               T +  + P+S P  +    +LG+ + + +     TS + G  S+  V +     GP 
Sbjct: 573  FQSTSSSPEIPLS-PEATLAKKSLGEPLPIGKPASSMTSPL-GVNSSASVIKTDSYAGPD 630

Query: 717  PAGTILK--LVT---------SADGKPTTIITTTQASGAGT-----KPTILGISSVSPST 760
             AG +LK  L+T         SAD  P  +  TT A G  T      P + G  S++P  
Sbjct: 631  SAGPLLKSSLITPTVAAFPLESAD--PAGVAPTT-AKGTSTYTTTASPFLEGTVSLAPKN 687

Query: 761  --TKPGTTTIIKTIPM---------SAIITQAGATGVTSSPGIKSPITIITTKVMTSGTG 809
               K GT T +  +P          S   T A    +  +P I  P ++ +  +  +GT 
Sbjct: 688  HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEI--PKSVPSPSLPPAGTP 745

Query: 810  APAKII------TAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVS 863
               K +      +A+  +A+   +               GT+            +P+ VS
Sbjct: 746  PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS-----PSPLGVS 800

Query: 864  AVKPAVTTLVVKGTTGV-TTLGTVTGTVS---------TSLAGAGGHSTSASL--ATPIT 911
                       KG+ G  T +G ++  VS          SL+  G   + A+    TP +
Sbjct: 801  VSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860

Query: 912  TLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTP---TITMQPVSQPTQVTLITAPSG 968
              G     +   ++P  +T+   +T   +   L  P     T  P   P      ++P  
Sbjct: 861  PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKK 920

Query: 969  VEAQPVHDLPVSILASPTTE-QPTATVTIADSGQGDVQPGTVT-LVCSNPPCETHETGTT 1026
              A P    P  I ASP+ +  PT       S +G   P T +      PP  T  +   
Sbjct: 921  ARATPA---PKGIPASPSPKGAPTPPAATPPSPKGG--PATPSPKWAPTPPAATPPSPKG 975

Query: 1027 NTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG 1086
              AT +      G P P             A+   S  G       +    PP  T  + 
Sbjct: 976  GPATPSP----KGAPTP------------PAATPPSPKGGPATPSPKGAPTPPAVTPPSP 1019

Query: 1087 TTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAV 1146
              + A T         G S PP  T  +   + A T +   GA     A      G P  
Sbjct: 1020 KGSPAATPFPK-----GASTPPAATPPSPKGSPAATPLPK-GAPTTPAATLPSPKGGP-- 1071

Query: 1147 IRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSP 1206
                 AT +L+ A    +          +T     A   P +  P     +A  P   +P
Sbjct: 1072 -----ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126

Query: 1207 AFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSP 1266
                  P S K  L++P     P G  +   +T    +  +    P+ AP   +    SP
Sbjct: 1127 TTPAATPPSPKGGLATPP----PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182

Query: 1267 STTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHE 1326
               +   +      P    T   + PP     +     AT S  G+     + PP     
Sbjct: 1183 KGGLATPS------PKGAPTTPAATPP-----SPKGGLATPSPKGAPTTPAATPPSPKGG 1231

Query: 1327 TGTTHTATTATSNGGT-GQPEGG--QQPPAGRPCETHQTTSTGTTMSVSVG-ALLPDATS 1382
              T       T+   T   P+GG    PP G P     T    T  S+  G A  P   +
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAP-----TPPAATPPSLKGGLATPPHKGA 1286

Query: 1383 SHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSS 1442
             +  V +       P+ +P  G    AP P     + PP      GT       T    +
Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKG----APTPP---AATPPSPKGSPGTPPPKGAPTPPAVT 1339

Query: 1443 NQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPPPE 1502
               P    +      S++G     +S    T   ++   +    +T  +P  GP++P P+
Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPK 1399

Query: 1503 ELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQ-TPELPAAVDLS---STGEPSSG 1558
                SP     + P    ++ +T +  E A   S    TP     V L    +T  P  G
Sbjct: 1400 GDPTSPA----VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455

Query: 1559 QESAGSAVVATV-VVQPP----PPTQSEVDQLSLPQELMA-EAQAGTTTL-MVTGLTPEE 1611
              +  S    T+  V PP    PP   +V   S P++  A  A  G  TL  V   +P+E
Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515

Query: 1612 LAVTAAA--EAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAATVTQAELGH 1669
            +  T ++  +  A  A     +  A  A  +A     M    P  T  A  T  +A    
Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT-PAIPTPKEAPATP 1574

Query: 1670 LSAEGQEGQATT--------------IPIVLT-----QQELAALVQQQQLQEAQAQQQHH 1710
             S E     A T              IP  +T     +      V     ++  A     
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK 1634

Query: 1711 HLPTEALAPADSLND-PAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAPQP 1766
              PT       SL D P   ++   ++  TVP     LP+    + A     VAP P
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT-ALKEVLVAPAP 1690



 Score =  103 bits (256), Expect = 2e-21
 Identities = 348/1565 (22%), Positives = 528/1565 (33%), Gaps = 252/1565 (16%)

Query: 367  PARVQLVRANTNSLEVSWGAVATADS-YLLQLQKYDIPATAATATSPTPNPVPSVPANPP 425
            P  VQ   A   +L  S  +VA A+S  ++ L     P+   T  +  P+ V   P   P
Sbjct: 144  PHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTP 203

Query: 426  KSPAPAAAAP--AVQPLTQV--GITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQ 481
              P   +  P   V P+  +  G+  LPQ  P   TTT     P V  ++IS    +   
Sbjct: 204  SPPCIVSTVPYHCVTPMASIQSGVASLPQTTP---TTTLAIASPQVKDTTISSVLISPQN 260

Query: 482  GVPAVLKVTGPQA--------TTGTPLVTMRPASQAGKAPVTVTSLPA--GVRMVVPTQS 531
              P  L + GP +        T   P+VT   +SQ    P T    P   G  +    QS
Sbjct: 261  --PGSLSLKGPVSPPAALSLSTQSLPVVT---SSQKTAGPNTPPDFPISLGSHLAPLHQS 315

Query: 532  AQGTVIGSSPQMSGMAALAAAAAATQK-IPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLP 590
            + G+V     Q+ G    +A +  T K I    + T  S P+  +++  +        +P
Sbjct: 316  SFGSV-----QLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSR--NEVVP 368

Query: 591  ATVKV--ASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP----IITVHKSGTVTVA 644
            ATV      +P +   P+T  + +       S++ AT+ S  P    I+    + T    
Sbjct: 369  ATVAAFPVVAPSVDKGPST--ISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYP 426

Query: 645  QQAQVVTTVVGG----VTKTITLVKSP---------ISVPGGSALISNL------GKVMS 685
              AQ+  + VG     VT   T+  +P         +S P  S  ISN+        VM+
Sbjct: 427  LVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMA 486

Query: 686  VVQTKPVQTS-AVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQAS-- 742
             V  K   T  A T +    P     +    LP+  ++K  T  D      + T  AS  
Sbjct: 487  PVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKD------LQTVPASLE 540

Query: 743  GAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIK-SPITIITT 801
            GA   P   G+++    T  P    +++  P ++   Q+     +SSP I  SP   +  
Sbjct: 541  GAPFSPAQAGLTTKKDPTVLP----LVQAAPKNSPSFQS----TSSSPEIPLSPEATLAK 592

Query: 802  KVMTSGT--GAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTP 859
            K +      G PA  +T+   +   +    V +      P   G +L++       L+TP
Sbjct: 593  KSLGEPLPIGKPASSMTSPLGV---NSSASVIKTDSYAGPDSAGPLLKS------SLITP 643

Query: 860  VTV-----SAVKPAVTTLVVKGTTGVTTLGT--VTGTVSTSLAGAGGHSTSASLATPITT 912
                    SA    V     KGT+  TT  +  + GTVS +      H         +TT
Sbjct: 644  TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA---PKNHPVKEGT---LTT 697

Query: 913  LGTIATLSSQV-INPTAITVSAAQTTLTAAGGL--TTPTITMQPVSQPTQVTLITAPSGV 969
            L  + T S    + P+     A   TL  A  +  + P+ ++ P   P     +   S  
Sbjct: 698  LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS-- 755

Query: 970  EAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV--QPGTVTLVCSNP-PCETHETGTT 1026
                 H   ++ +AS   E PT      DSG        GT+T +  +P P     +  T
Sbjct: 756  -----HTSALAPVASSPKECPTE-----DSGASATASSKGTLTYLADSPSPLGVSVSPQT 805

Query: 1027 NTATT--------TVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNP 1078
                T        T + NL     P +  F+ +          S  G ++         P
Sbjct: 806  KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS-------LSFQGSKDSPATTHSPTP 858

Query: 1079 PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNT-------ATTAMSSVGANH 1131
            P  + +   T +A T  S      G + PP ET      N        AT A     A  
Sbjct: 859  P--SPKGAPTPSAVTPLS----PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALS 912

Query: 1132 QRDARRACAAGTPAVIRISVATGALEA-AQGSKSQCQTRQTSATSTTMTVMATGAPCSAG 1190
               +    A  TPA   I  +     A    + +    +   AT +        A     
Sbjct: 913  MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972

Query: 1191 PLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLP--------AGRHSHAVST--- 1239
            P  GP+     G  +P      P S K   ++PS K  P        + + S A +    
Sbjct: 973  PKGGPATPSPKGAPTPPAA--TPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030

Query: 1240 AAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHET 1299
             A T  +     P+ +P    L  G+P TT   T       P+    +    PP  T  +
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAP-TTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089

Query: 1300 GTTNTATTSNAGSAQRVCSNPPCETHETGTT-HTATTATSNGGTGQPEGG--QQPPAGRP 1356
                 AT S  G+     + PP       T  H     T       P+GG    PP G P
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149

Query: 1357 CETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRV 1416
                 TT   T  S   G   P    +  T          P+ TP +    LA  P+ + 
Sbjct: 1150 -----TTPAATPPSPKGGLATPPPKGAPTT----------PAATPPSPKGGLAT-PSPKG 1193

Query: 1417 CSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTV 1476
                P  T  +     AT       +     PAA+      S +G     +   A TT  
Sbjct: 1194 APTTPAATPPSPKGGLATPSPKGAPTT----PAATPP----SPKGGLATPSPKGAPTTPA 1245

Query: 1477 SSTLTRAVTTVTQSTPVPGPSVPPPEELQVSPG------------PRQQLPPRQLLQSAS 1524
            +          T  +P  GP+ PPP+     P             P  +  P   + +  
Sbjct: 1246 A----------TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295

Query: 1525 TALMGESAEVLSASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQ 1584
            +   G +      + TP  PAA   S  G P +          A   V PP P  +    
Sbjct: 1296 SPKGGPATSPPKGAPTP--PAATPPSPKGSPGTPPPKGAPTPPA---VTPPSPKGTP--- 1347

Query: 1585 LSLPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQAL-------AIQA 1637
             +LP    +     TT     G TP     +     A    + +   A+          A
Sbjct: 1348 -TLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406

Query: 1638 VLQAAQQAVMGTGEPMDTSEAAAT----------VTQAELGHLSAEGQEGQATTIPIVLT 1687
            V+  + +    T  P+ T E AAT          VT   L    A          P    
Sbjct: 1407 VIPLSPKKAPAT--PV-TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 1688 QQELAALVQQQQLQE-AQAQQQHHHLPTEALAPADSLNDPAIESNCLNELAGTVPSTVAL 1746
               L A+      +  A  Q      P +A A    +  P + +     +  + P  V  
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA-----VIPSSPKEVPA 1518

Query: 1747 LPSTATESLAPSNTFVAPQPVVVASPAKLQAAATLTEVANGIESLGVKPDLPPPPS--KA 1804
             PS+  + +AP+ T ++ +     +PA L     L   A  + S    P +P P      
Sbjct: 1519 TPSSRRDPIAPTATLLSKK-----TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPAT 1573

Query: 1805 PMKKE 1809
            P  KE
Sbjct: 1574 PSSKE 1578



 Score =  101 bits (251), Expect = 9e-21
 Identities = 317/1433 (22%), Positives = 477/1433 (33%), Gaps = 217/1433 (15%)

Query: 418  PSVPANPPKSPAPAAAAPAV-----------QPLTQVGITLLPQAAPAPPTTTTIQVLPT 466
            P+V A P +S  PA  AP              P  +  ++L P+  P    T T   LP 
Sbjct: 643  PTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLT--TLPL 700

Query: 467  VPGSSISVPTAARTQGV--PAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVR 524
            VP +S + P A   Q    P    V  P+     P  ++ PA             P G +
Sbjct: 701  VPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT-----------PPGTK 749

Query: 525  MV--VPTQSAQGTVIGSSPQM----SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVK 578
             V  +   SA   V  S  +     SG +A A++      +  S +P  +SV   T    
Sbjct: 750  KVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPP 809

Query: 579  TMAVTPGTTTLPATVKVASSPVMVS--------------NPATRMLKTAAAQVGTSVSSA 624
            T   + G  T    +    SPV  S              +PAT    T  +  G    SA
Sbjct: 810  TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869

Query: 625  TN-------------TSTRPIITVH--KSGTVTVAQQAQVVTTVVGGVTKTITLVKSPIS 669
                           T T  ++ +   K G  T A +     ++     K      +P  
Sbjct: 870  VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929

Query: 670  VPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILK-----L 724
            +P   +            +  P   +A       GP T   +     PA T         
Sbjct: 930  IPASPS-----------PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA 978

Query: 725  VTSADGKPTTIITTTQASGAGTK-------PTILGISSVSPSTTKPGTTTIIK---TIPM 774
              S  G PT    T  +   G         PT   ++  SP  + P  T   K   T P 
Sbjct: 979  TPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS-PAATPFPKGASTPPA 1037

Query: 775  SAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVV 834
            +   +  G+   T  P         T      G   P+      P  AT    +G     
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 835  L-KGAPGQPGTILRTVPMGGVRLVTPVTVSA-VKPAVTTLVVKGTTGVTT---LGTVTGT 889
              KGAP  P     + P GG  L TP    A   PA T    KG  G+ T    G  T  
Sbjct: 1098 SPKGAPMPPAATPPS-PKGG--LATPPHKGAPTTPAATPPSPKG--GLATPPPKGAPTTP 1152

Query: 890  VSTSLAGAGGHST-------SASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAG 942
             +T  +  GG +T       +   ATP +  G +AT S     P     + A T  +  G
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS-----PKGAPTTPAATPPSPKG 1207

Query: 943  GLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQG 1002
            GL TP+    P    T      +P G  A P      S   +PTT  P AT      G  
Sbjct: 1208 GLATPSPKGAPT---TPAATPPSPKGGLATP------SPKGAPTT--PAATPPSPKGGPA 1256

Query: 1003 DVQP-GTVTLVCSNPP------CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEA 1055
               P G  T   + PP            G  N A  T  +  GG P  +  +        
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG-PATSPPK---GAPTP 1312

Query: 1056 AASLVTSTVGQQNGSVVRVCSNPPCETHET--GTTNTATTATSNMAGQHGCSNPPCETHE 1113
             A+   S  G       +    PP  T  +  GT     T  S+  G      P   + +
Sbjct: 1313 PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG------PTTPSSK 1366

Query: 1114 TGTTNTATTAMSSVG-ANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTS 1172
             G T  A T     G A      +R  A  +P     S A   L   +   +   TR+ +
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV-TREGA 1425

Query: 1173 ATST--------TMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPS 1224
            AT +           V    AP ++ P  GP+     G   P    + P S K   +   
Sbjct: 1426 ATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG--DPTLPAVTPPSPKEPPAPKQ 1483

Query: 1225 IKDLPAGRHSHAVST--AAMTRSSVGAGEPRMAPVCESLQGG---------SPSTTVTVT 1273
            +    + + + A      A T  +V    P+  P   S +           S  T  T+ 
Sbjct: 1484 VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA 1543

Query: 1274 ALEALLCPSATVTQVCSNP----PCETHETGTTN--------TATTSNAGSAQRVCSNPP 1321
              EAL+ P+ TV      P    P E   T ++         T +T     + +    PP
Sbjct: 1544 PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP 1603

Query: 1322 CETH----ETGTTHTATTATSNGG--TGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGA 1375
              T     E  T    T  +   G  T  P+G    P   P     + ++  +++  +GA
Sbjct: 1604 AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA 1663

Query: 1376 LLPDATSS-----HRTVESGLEVAAAPSVTPQAGTALLAPFPTQR-------VCSNPPCE 1423
             +P A+         T    + VA AP  TP           T++       +C +P  +
Sbjct: 1664 TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723

Query: 1424 THETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
                G   T       +   +D    A  +    S +G       S A T   ++   + 
Sbjct: 1724 NGSKGPLSTVAPAPL-LPVQKDSSKTAKGKDASHSPKGPLAP-PESKASTPLTAAAFEKV 1781

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGES-AEVLSASQTPE 1542
            +     ++    PS  PP  L ++P P   LPP+Q    +S  L+ ES ++ L+ +   E
Sbjct: 1782 LPKPESASVSAAPS--PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDE 1839

Query: 1543 LPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTL 1602
            L   +      EP SG    G    + +V  P P +          ++ + +   G+ T 
Sbjct: 1840 LLPLI----PPEPISG----GVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTE 1891

Query: 1603 MVTGLTPEEL-------AVTAAAEAAAQAAATEEAQALAIQAVLQ-AAQQAVMGTGEPMD 1654
              +  +  EL       A T  A+ AA A   EE  + A Q+  +  A++A+   G    
Sbjct: 1892 SDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQV 1951

Query: 1655 TSEAAATVTQAE---LGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQ 1704
            T     T+ +++         +  +  A+   IV  + ++  L QQ QL  A+
Sbjct: 1952 TGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAE 2004



 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 336/1602 (20%), Positives = 506/1602 (31%), Gaps = 313/1602 (19%)

Query: 402  IPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTI 461
            +P  A      T   +P   A     P  +A +     L Q G TL P  +PAP      
Sbjct: 1    MPGEATETVPATEQELPQPQAETAVLPMSSALS-VTAALGQPGPTLPPPCSPAPQ----- 54

Query: 462  QVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521
                         P +A  Q  P       P     TPL    P S +G      T+LP 
Sbjct: 55   -----------QCPLSAANQASP----FPSPSTIASTPLEVPFPQSSSG------TALPL 93

Query: 522  GVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQK-IPPSSAPTVLSVPAGTTIVKTM 580
            G     PT      +IG     + +A  +   A T K  P SSAP  L   A  ++ K+ 
Sbjct: 94   GTAPEAPT--FLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSS 151

Query: 581  AVTPGTTTLPATVKVA--------SSPVMVSNPATRMLKTAAAQV----GTS-----VSS 623
            A  P   T P +V VA        S+P+  S P T + K  +  V    GT      VS+
Sbjct: 152  AFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVST 211

Query: 624  ATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKV 683
                   P+ ++ +SG  ++ Q     T  +       T + S +  P     +S  G V
Sbjct: 212  VPYHCVTPMASI-QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPV 270

Query: 684  MS------VVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIIT 737
                      Q+ PV TS+   Q + GP T       P+  G+ L  +  +      ++ 
Sbjct: 271  SPPAALSLSTQSLPVVTSS---QKTAGPNT---PPDFPISLGSHLAPLHQSSFGSVQLLG 324

Query: 738  TTQASGAGTKPTILGISSVSPST--TKPGTTTIIKTIP-MSAIITQAGATGVTSSPGI-K 793
             T  S A + PT+  IS    ST  + P   ++I  +P  + ++    A     +P + K
Sbjct: 325  QTGPS-ALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDK 383

Query: 794  SPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG----------QPG 843
             P TI +     SG+            +AT       T ++LK +P            P 
Sbjct: 384  GPSTISSITCSPSGS----------LNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPV 433

Query: 844  TILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTS-----LAGAG 898
            + + T P+    +VT     A  P  T  V    +   + G ++    TS     +A   
Sbjct: 434  SSVGTTPL----VVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA 489

Query: 899  GHSTSASLAT--------PITTLGTIATLSSQVI--NPTAITVSAAQTTLTAA------G 942
                S  +AT        P+     +  L S V+   PT   +     +L  A       
Sbjct: 490  PKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549

Query: 943  GLTT-------PTITMQPVSQPTQVTLITAPSGVEAQPVHDL-------------PVSIL 982
            GLTT       P +   P + P+  +  ++P  +   P   L             P S +
Sbjct: 550  GLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPE-IPLSPEATLAKKSLGEPLPIGKPASSM 608

Query: 983  ASPTTEQPTATVTIADSGQGDVQPG------TVTLVCSNPPCETHETG--------TTNT 1028
             SP     +A+V   DS  G    G       +T   +  P E+ +           T+T
Sbjct: 609  TSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTST 668

Query: 1029 ATTTVVANLGG--------HP-----------QPTQVQ---FVCDRQEAAASLVTSTVGQ 1066
             TTT    L G        HP            PT  +        Q   A L T  +  
Sbjct: 669  YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAP 728

Query: 1067 QNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMS- 1125
            +    V   S PP  T   GT      + ++       S   C T ++G + TA++  + 
Sbjct: 729  EIPKSVPSPSLPPAGT-PPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787

Query: 1126 ------------SVGANHQRDARRACAAGTPAVI-RISVATGALEAA---------QGSK 1163
                        SV    +R   +  +AG    I  +S     +EA+         QGSK
Sbjct: 788  TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSK 847

Query: 1164 SQCQTRQ-----------TSATSTTMTVMATGAPCSAGPLLGPSMAREP----GGRSPAF 1208
                T             T +  T ++      P    P   PS+   P    G  +PA 
Sbjct: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT--PSVVNLPFPKEGPATPAP 905

Query: 1209 VQLAPL-----SSKVRLSSPSIKDLPA-----GRHSHAVSTAAMTRSSVGAGEPRMAPVC 1258
             Q   L     S K   ++P+ K +PA     G  +   +T    +       P+ AP  
Sbjct: 906  KQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965

Query: 1259 ESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATTSNAGSAQRVCS 1318
             +    SP              P+    +    PP  T  +     AT S  G+      
Sbjct: 966  PAATPPSPKGG-----------PATPSPKGAPTPPAATPPSPKGGPATPSPKGA-----P 1009

Query: 1319 NPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLP 1378
             PP  T  +     A T    G +  P      P G P  T       TT + ++ +  P
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS--P 1067

Query: 1379 DATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCET------------HE 1426
                +  +++      AA   +P+ G A     P+ +    PP  T            H+
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPAT----PSPKGAPMPPAATPPSPKGGLATPPHK 1123

Query: 1427 TGTTHTATTVTSNMSSNQDPPP---AASDQGEVESTQGDSVNITSSSAITTTVSSTLTRA 1483
               T  A T  S       PPP     +      S +G         A TT  +      
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA------ 1177

Query: 1484 VTTVTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
                T  +P  G + P P+    +P      P   L                S    P  
Sbjct: 1178 ----TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP-------------SPKGAPTT 1220

Query: 1544 PAAVDLSSTGEPSSGQESAGSAVVATVVVQP------PPPTQSEVDQLSLPQELMAEAQA 1597
            PAA   S  G  ++          A     P      PPP  +     + P  L    + 
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSL----KG 1276

Query: 1598 GTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSE 1657
            G  T    G  P    VT  +     A +  +  A    A    + +   GT  P     
Sbjct: 1277 GLATPPHKG-APNPAVVTPPSPKGGPATSPPKG-APTPPAATPPSPKGSPGTPPPKGAPT 1334

Query: 1658 AAATVTQAELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQEAQAQQQHHHLPTEAL 1717
              A    +  G            T+P      +        +           H    A+
Sbjct: 1335 PPAVTPPSPKG----------TPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384

Query: 1718 APADSLNDPAIESNCLNELAGTV----PSTVALLPSTATESLAPSNTFVAPQPVVVASPA 1773
             P      PAI S   +  +  V    P      P T   +  PS   + P  V   +P 
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV---TPV 1441

Query: 1774 KLQAAATLTEVANGIESLGVKPD------LPPPPSKAPMKKE 1809
             L+ A   +    G  +   K D       PP P + P  K+
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ 1483



 Score = 54.7 bits (130), Expect = 9e-07
 Identities = 89/386 (23%), Positives = 135/386 (34%), Gaps = 68/386 (17%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            PA    ATS +P   P+ PA     P  A   PAV P +       P+  PA P++    
Sbjct: 1479 PAPKQVATSSSPKKAPATPA-----PMGAPTLPAVIPSS-------PKEVPATPSSRRDP 1526

Query: 463  VLPTVPGSSISVPT--AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGK--------A 512
            + PT    S   P   A +   +P  + V  P+ T   P     PA+ + K         
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586

Query: 513  PVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAP--TVLSV 570
            P T    P+   +++P       V   SP+       A    + +K P + AP  T  S 
Sbjct: 1587 PSTYKGAPSPKELLIPP-----AVTSPSPK-EAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640

Query: 571  PAGTTIVKTMAVTPGTTT--LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTS 628
            P   + +K    +P + T  + ATV  AS  +      T + +   A    S        
Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST------- 1693

Query: 629  TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQ 688
              PIIT                 T  G  TK  +    PI  P  SA   + G + +V  
Sbjct: 1694 --PIIT---------------APTRKGPQTKKSSATSPPI-CPDPSAKNGSKGPLSTVAP 1735

Query: 689  TKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP 748
               +     + + + G        KGPL            + K +T +T         KP
Sbjct: 1736 APLLPVQKDSSKTAKGKDAS-HSPKGPL---------APPESKASTPLTAAAFEKVLPKP 1785

Query: 749  TILGISSV-SPSTTKPGTTTIIKTIP 773
                +S+  SP  + P   + + T+P
Sbjct: 1786 ESASVSAAPSPPVSLPLAPSPVPTLP 1811



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 93/426 (21%), Positives = 153/426 (35%), Gaps = 69/426 (16%)

Query: 406  AATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLP 465
            AAT +     P    P +  K+PA +A                P+  PA P++     LP
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSA----------------PKGGPATPSSKGDPTLP 1468

Query: 466  TVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRM 525
             V   S   P A +      V   + P+    TP            AP+   +LPA    
Sbjct: 1469 AVTPPSPKEPPAPK-----QVATSSSPKKAPATP------------APMGAPTLPA---- 1507

Query: 526  VVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPG 585
                      VI SSP+         A  ++++ P +   T+LS     T+    A+ P 
Sbjct: 1508 ----------VIPSSPKE------VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551

Query: 586  TTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQ 645
              T+P+  K  + P     PAT   K A++    + S+     +   + +  + T    +
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611

Query: 646  QAQVVTTVVGGVTKTITLVKSPISVPGGSALI-SNLGKVMSVVQTKPVQTSAVTGQASTG 704
            +A     V     +      +P   P    +  S+L    +   +   +  A   QAS G
Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671

Query: 705  PVTQIIQTKGPLPAGTILKLVTSADG-KPTTIITTTQASGAGTKPTILGISSVSPS-TTK 762
                +   KGP    T LK V  A   + T IIT     G  TK +      + P  + K
Sbjct: 1672 ----LPAKKGP----TALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAK 1723

Query: 763  PGTTTIIKTIPMSAII-----TQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITA 817
             G+   + T+  + ++     +   A G  +S   K P+    +K  T  T A  + +  
Sbjct: 1724 NGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLP 1783

Query: 818  VPKIAT 823
             P+ A+
Sbjct: 1784 KPESAS 1789



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 52/207 (25%), Positives = 80/207 (38%), Gaps = 27/207 (13%)

Query: 402  IPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTI 461
            +P+   T   PTP   P+ P     S   A++ PAV P T  G    P+    PP  T+ 
Sbjct: 1555 VPSPKKTPAIPTPKEAPATP-----SSKEASSPPAVTPSTYKGAP-SPKELLIPPAVTSP 1608

Query: 462  QVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521
                     +++ P+  +    PA      P+ T  +P VT      +  +P +VT    
Sbjct: 1609 SPKEAPTPPAVTPPSPEKGPATPA------PKGTPTSPPVTPSSLKDSPTSPASVT---C 1659

Query: 522  GVRMVVPTQSAQGTVIGSSPQMSGMAAL--AAAAAATQKIPPSSAPTVLSVPAGTTIVKT 579
             +   VP Q+++G      P   G  AL     A A +  P  +APT      G    K+
Sbjct: 1660 KMGATVP-QASKGL-----PAKKGPTALKEVLVAPAPESTPIITAPT----RKGPQTKKS 1709

Query: 580  MAVTPGTTTLPATVKVASSPVMVSNPA 606
             A +P     P+    +  P+    PA
Sbjct: 1710 SATSPPICPDPSAKNGSKGPLSTVAPA 1736



 Score = 32.0 bits (71), Expect = 6.3
 Identities = 54/231 (23%), Positives = 80/231 (34%), Gaps = 40/231 (17%)

Query: 399  KYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPL---------TQVGITLLP 449
            K   P TAA      P P  +  +  P  P     AP+  P          +  G+ L  
Sbjct: 1768 KASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLES 1827

Query: 450  QAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP--AVLKVTGPQATTGTPLVTMRPAS 507
             + P  P     ++LP +P   IS        GVP  +VL       + G P+ T     
Sbjct: 1828 PSKPLAPADED-ELLPLIPPEPIS-------GGVPFQSVLVNMPTPKSAGIPVPT----- 1874

Query: 508  QAGKAPVTVTSLPAGVRM----VVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSS 563
             + K PVT  +  +G        VP    Q      S Q +   A  AAAA   + P S 
Sbjct: 1875 PSAKQPVTKNNKGSGTESDSDESVPELEEQ-----DSTQATTQQAQLAAAAEIDEEPVSK 1929

Query: 564  APTVLSVPAGTTIVKTMAVTPGTTTLPATVK-------VASSPVMVSNPAT 607
            A    S       +  + +   T     T++       V + P +  +PA+
Sbjct: 1930 AKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPAS 1980


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score =  118 bits (295), Expect = 7e-26
 Identities = 251/1154 (21%), Positives = 413/1154 (35%), Gaps = 200/1154 (17%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            P ++ T+T+PT      V   PP     +A    V P + + IT+   + P     TT Q
Sbjct: 95   PVSSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTSFI-ITI---SHPTSICVTTTQ 150

Query: 463  VLPT-----VPGSSISVPTAARTQGVPAVLKVTG-----PQATTG--TPLVTMRPASQAG 510
            V  T      P +   V T   T  +    K T      P  TT   TP+VT+ P+S + 
Sbjct: 151  VAFTSSYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPSSVSA 210

Query: 511  KAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSV 570
                  T++ +  R    T    G++  ++        L  A  +T              
Sbjct: 211  TDTTFHTTISSTTRTTERTPLPTGSIHTTTSPTPVFTTLKTAVTSTS------------- 257

Query: 571  PAGTTIVKTMAVTPGTTTL--PATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTS 628
            P  ++I  T  VT  TTT   P      SSP       TR + ++   + T   ++  T+
Sbjct: 258  PITSSITSTNTVTSMTTTASQPTATNTLSSP-------TRTILSSTPVLSTETITSGITN 310

Query: 629  TRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQ 688
            T P+ T+  +   T+++      T     + T T+  S   +   +++   L    S+  
Sbjct: 311  TTPLSTLVTTLPTTISRSTPTSETTYP-TSPTSTVTDSTTKIAYSTSMTGTLSTETSL-- 367

Query: 689  TKPVQTSAVTGQASTGPVTQIIQTKGPLPA--------GTILKLVTS-ADGKPTTIITTT 739
              P  +S  T + +T P+T ++ T   + +         TI   VTS +  + T+ ITTT
Sbjct: 368  -PPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTT 426

Query: 740  Q----------ASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSS 789
            +          +S   TK T    S  SPS T   TTT   +    +  +    T  TS 
Sbjct: 427  ETPSHSTPRFTSSFTNTKTT----SHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSH 482

Query: 790  PGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQG------VTQVVLKGAPGQPG 843
                   +I TT+  +  T +    IT        H           T+      P    
Sbjct: 483  SARSFTSSITTTETTSHNTRSFTSSITTTE--TNSHSTTSFTSSITTTETTSHSTPSFSS 540

Query: 844  TI------LRTVPMGGVRLVTPVTVSAVKPAVTTLVVK------GTTGVTTLGTVTGTVS 891
            +I      L + P     + T  T S + P +T+ +         T G T+  T T T S
Sbjct: 541  SITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTS 600

Query: 892  TSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITM 951
             S       +  ++++T  T + +  T S   + PT +T S+  T +      TT   T+
Sbjct: 601  ESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIP-----TTSLRTL 655

Query: 952  QPVSQPTQVTLITA------PSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQ 1005
             P S  T  +L T       P+ +   P       I++S  + Q T T ++  +    + 
Sbjct: 656  TPSSVGTSTSLTTTTDFPSIPTDISTLPTR---THIISSSPSIQSTETSSLVGTTSPTMS 712

Query: 1006 PGTVTL-VCSNPPCETHETGT-----TNTATTTVVANLGG---HPQPTQVQFVCDRQEAA 1056
               +TL +  N P  +  T       T T T  V+ +  G    P PT V F      + 
Sbjct: 713  TVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTSPAPTTVTFG-STDSST 771

Query: 1057 ASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGT 1116
            ++L T T      ++V     P   TH +    T +T             P  +T  T T
Sbjct: 772  STLHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPST-------------PSLQTSLTST 818

Query: 1117 TNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATST 1176
            +   T + +                      R S +T A+           +  T   S+
Sbjct: 819  SEFTTESFT----------------------RGSTSTNAI---------LTSFSTIIWSS 847

Query: 1177 TMTVMATGAPCSAG--PLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
            T T++ + +P SA   P+   ++   P   SP       + S   + S SI   P+   S
Sbjct: 848  TPTIIMSSSPSSASITPVFSTTIHSVPS--SPY------IFSTENVGSASITGFPSLSSS 899

Query: 1235 HAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPC 1294
               ST++ T SS+      + P         PSTT     +   + P A+ T  C     
Sbjct: 900  ATTSTSS-TSSSLTTALTEITPFSYI---SLPSTTPCPGTITITIVP-ASPTDPCVEMDP 954

Query: 1295 ETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAG 1354
             T  T    T  T    + + V          T TT+  T++              P + 
Sbjct: 955  STEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTYMDTSS------------MMPESE 1002

Query: 1355 RPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQ 1414
                 + ++STGT             T    TV +   +   P+       + + P P  
Sbjct: 1003 SSISPNASSSTGT------------GTVPTNTVFTSTRL---PTSETWLSNSSVIPLPLP 1047

Query: 1415 RVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITT 1474
             V + P   T +  ++      TS+ S++  PP   + +  V +TQ  +   T +S  TT
Sbjct: 1048 GVSTIPL--TMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPT---TLTSRRTT 1102

Query: 1475 TVSSTLTRAVTTVT 1488
             ++S +T   T  T
Sbjct: 1103 RITSQMTTQSTLTT 1116



 Score =  103 bits (256), Expect = 2e-21
 Identities = 253/1119 (22%), Positives = 411/1119 (36%), Gaps = 196/1119 (17%)

Query: 437  VQPLTQVGITLLPQAAP-APPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQAT 495
            +Q L  +G+  + +A+P A  T +T         +SIS     R +   AVL    P + 
Sbjct: 1    MQLLGLLGLLWMLKASPWATGTLST--------ATSISQVPFPRAEAASAVLS-NSPHSR 51

Query: 496  --TGTPLVTMRPASQAG----KAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMA-- 547
               G PL   + AS A      AP+T+T+ P    +     ++  +   S+   S  A  
Sbjct: 52   DLAGWPLGVPQLASPAPGHRENAPMTLTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFK 111

Query: 548  ------ALAAAAAATQKIPPSSAPTVLSVPAGTTIVKT-MAVTPGTTTLPATVKVASSPV 600
                   +   +A T+ + P+S    +S P    +  T +A T   T+ P T K  ++  
Sbjct: 112  VETTPPTVLVYSATTECVYPTSFIITISHPTSICVTTTQVAFTSSYTSTPVTQKPVTTVT 171

Query: 601  MVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKT 660
               +  T    T+A    TS  S T     PI+TV  S   +V+       T +   T+T
Sbjct: 172  STYSMTTTEKGTSAM---TSSPSTTTARETPIVTVTPS---SVSATDTTFHTTISSTTRT 225

Query: 661  ITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGT 720
                  P             G + +     PV T+  T   ST P+T  I +       T
Sbjct: 226  TERTPLPT------------GSIHTTTSPTPVFTTLKTAVTSTSPITSSITS-----TNT 268

Query: 721  ILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQ 780
            +  + T+A  +PT   T T +S     PT   +SS    +T+  T+ I  T P+S ++T 
Sbjct: 269  VTSMTTTAS-QPTA--TNTLSS-----PTRTILSSTPVLSTETITSGITNTTPLSTLVTT 320

Query: 781  AGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPG 840
               T   S+P          T   T  T   + +  +  KIA               +  
Sbjct: 321  LPTTISRSTP----------TSETTYPTSPTSTVTDSTTKIAY--------------STS 356

Query: 841  QPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGH 900
              GT+     +       P T +A  P   T +V  TT +++  T + + ST  +    H
Sbjct: 357  MTGTLSTETSLPPTSSSLPTTETATTP--MTNLVTTTTEISSHSTPSFSSSTIYSTVTSH 414

Query: 901  STSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQV 960
            ST     + ITT  T +  + +  +    T + +  + +    +TT   T    S P+  
Sbjct: 415  ST-PRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSH--STPSFT 471

Query: 961  TLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCET 1020
            + IT  +   +        SI  + TT   T + T + +        T +   S    ET
Sbjct: 472  SSITT-TETTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTET 530

Query: 1021 --HETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNP 1078
              H T + +++ TT    L  H  P    +V   +    S +T  +     +      + 
Sbjct: 531  TSHSTPSFSSSITTTETPL--HSTPGLTSWVTTTK--TTSHITPGLTSSITTTETTSHST 586

Query: 1079 PCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRA 1138
            P  T    TT T + +T +++     S          T +T+TTA++S    H   +  A
Sbjct: 587  PGFTSSITTTETTSESTPSLSSSTIYS----------TVSTSTTAITS----HFTTSETA 632

Query: 1139 CAAG--TPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPS 1196
                  TP+ +   + T +L           T  +  TST++T               PS
Sbjct: 633  VTPTPVTPSSLSTDIPTTSLRTL--------TPSSVGTSTSLTTTTD----------FPS 674

Query: 1197 MAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAP 1256
            +        P  +   P  + +  SSPSI+             +  T S VG   P M+ 
Sbjct: 675  I--------PTDISTLPTRTHIISSSPSIQ-------------STETSSLVGTTSPTMST 713

Query: 1257 VCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNT--ATTSNAGSAQ 1314
            V  +L+  + +T ++  +   ++ P  T TQ    PP  T  TGT  +   TT   GS  
Sbjct: 714  VRMTLR-ITENTPISSFSTSIVVIPE-TPTQ---TPPVLTSATGTQTSPAPTTVTFGSTD 768

Query: 1315 RVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVG 1374
                        T T HT T +T+          Q P       T QTT +  ++  S+ 
Sbjct: 769  ----------SSTSTLHTLTPSTALSTI--VSTSQVPIPSTHSSTLQTTPSTPSLQTSL- 815

Query: 1375 ALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTAT 1434
                  ++S  T ES    + + +       A+L  F T    S P      + ++ + T
Sbjct: 816  -----TSTSEFTTESFTRGSTSTN-------AILTSFSTIIWSSTPTIIMSSSPSSASIT 863

Query: 1435 TVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTT--VSSTLTRAVTTVT---- 1488
             V S    +    P       V S         SSSA T+T   SS+LT A+T +T    
Sbjct: 864  PVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSY 923

Query: 1489 ----QSTPVPG-------PSVPPPEELQVSPGPRQQLPP 1516
                 +TP PG       P+ P    +++ P      PP
Sbjct: 924  ISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPP 962



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 182/790 (23%), Positives = 283/790 (35%), Gaps = 96/790 (12%)

Query: 858  TPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIA 917
            TP TV     + TT  V  T+ + T+   T    T+   A    TS+  +TP+T      
Sbjct: 115  TPPTVLVY--SATTECVYPTSFIITISHPTSICVTTTQVA---FTSSYTSTPVTQKPVTT 169

Query: 918  TLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDL 977
              S+  +  T    SA  ++ +      TP +T+ P S     T          +     
Sbjct: 170  VTSTYSMTTTEKGTSAMTSSPSTTTARETPIVTVTPSSVSATDTTFHTTISSTTRTTERT 229

Query: 978  PVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANL 1037
            P+   +  TT  PT   T   +      P T ++  +N       T +  TAT T+ +  
Sbjct: 230  PLPTGSIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPT 289

Query: 1038 GGHPQPTQVQFVCDRQEAAASLVTST------VGQQNGSVVRVCSNPPCE-THETGTTNT 1090
                  T V       E   S +T+T      V     ++ R  S P  E T+ T  T+T
Sbjct: 290  RTILSSTPVL----STETITSGITNTTPLSTLVTTLPTTISR--STPTSETTYPTSPTST 343

Query: 1091 ATTATSNMAGQHGCSNP-------PCETHETGTTNTATTAMSSVGANHQRDARRACAAGT 1143
             T +T+ +A     +         P  +    TT TATT M+++       +  +  + +
Sbjct: 344  VTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISSHSTPSFS 403

Query: 1144 PAVIRISVATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSM--AREP 1201
             + I  +V            S    R TS+ +TT T      P  + P    S    +  
Sbjct: 404  SSTIYSTVT-----------SHSTPRFTSSITTTET------PSHSTPRFTSSFTNTKTT 446

Query: 1202 GGRSPAFVQLAPLSSKVRLSSP----SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPV 1257
              RSP+F  L   +     S+P    SI       HS    T+++T +   +   R    
Sbjct: 447  SHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFT- 505

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCS-NPPCETHETGTTNTATTSNAGSAQRV 1316
                   S +TT T +        S T T+  S + P  +    TT T   S  G    V
Sbjct: 506  ------SSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWV 559

Query: 1317 CSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSVSVGAL 1376
                   T    T+H     TS+  T +      P       T +TTS  +T S+S   +
Sbjct: 560  -------TTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTSE-STPSLSSSTI 611

Query: 1377 LPDATSSHRTVESGLEVA-AAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGTTHTATT 1435
                ++S   + S    +  A + TP   ++L    PT  + +  P      GT+ + TT
Sbjct: 612  YSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTP---SSVGTSTSLTT 668

Query: 1436 VTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPG 1495
             T   S   D     +    + S+       TSS   TT+ + +  R    +T++TP+  
Sbjct: 669  TTDFPSIPTDISTLPTRTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISS 728

Query: 1496 PSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPELPAAVDLSSTGEP 1555
             S      + V P    Q PP  +L SA            + +QT   P  V   ST   
Sbjct: 729  FST----SIVVIPETPTQTPP--VLTSA------------TGTQTSPAPTTVTFGSTDSS 770

Query: 1556 SS-----GQESAGSAVVATVVVQPPPPTQSEVDQL--SLP--QELMAEAQAGTTTLMVTG 1606
            +S        +A S +V+T  V P P T S   Q   S P  Q  +      TT     G
Sbjct: 771  TSTLHTLTPSTALSTIVSTSQV-PIPSTHSSTLQTTPSTPSLQTSLTSTSEFTTESFTRG 829

Query: 1607 LTPEELAVTA 1616
             T     +T+
Sbjct: 830  STSTNAILTS 839



 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 153/661 (23%), Positives = 250/661 (37%), Gaps = 75/661 (11%)

Query: 405  TAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQP-LTQVGITLLPQAAPAPPTTTTIQV 463
            ++ T T  T +  PS  ++   +  P  + P +   +T    T           TTT   
Sbjct: 523  SSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETT 582

Query: 464  LPTVPGSSISVPTAART-QGVPAVLKVT--GPQATTGTPLVTMRPASQAGKAPVTVTSLP 520
              + PG + S+ T   T +  P++   T     +T+ T + +    S+    P  VT  P
Sbjct: 583  SHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVT--P 640

Query: 521  AGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLS-VPAGTTIVKT 579
            + +   +PT S + T+  SS         + +   T   P  S PT +S +P  T I+ +
Sbjct: 641  SSLSTDIPTTSLR-TLTPSS------VGTSTSLTTTTDFP--SIPTDISTLPTRTHIISS 691

Query: 580  MAVTPGTTT--LPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHK 637
                  T T  L  T     S V ++   T     ++      V   T T T P++T   
Sbjct: 692  SPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLT--- 748

Query: 638  SGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAV 697
              + T  Q +   TTV  G T + T     ++        + L  ++S  Q     T + 
Sbjct: 749  --SATGTQTSPAPTTVTFGSTDSSTSTLHTLTPS------TALSTIVSTSQVPIPSTHSS 800

Query: 698  TGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVS 757
            T Q  T P T  +QT     +    +  T        I+T+       + PTI+  SS S
Sbjct: 801  TLQ--TTPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPS 858

Query: 758  PSTTKPGTTTIIKTIPMSAII---TQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKI 814
             ++  P  +T I ++P S  I      G+  +T  P + S  T  T+   +S T A  +I
Sbjct: 859  SASITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEI 918

Query: 815  ITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVV 874
                                    P    ++  T P  G   +T V  S   P V    +
Sbjct: 919  -----------------------TPFSYISLPSTTPCPGTITITIVPASPTDPCVE---M 952

Query: 875  KGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAA 934
              +T  T+  T   TV           TS S+ T +TT   + T S    + ++I+ +A+
Sbjct: 953  DPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLTTY--MDTSSMMPESESSISPNAS 1010

Query: 935  QTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPV-SILASPTTEQPTAT 993
             +T T     T PT T+      T   L T+ + +    V  LP+  +   P T +P+++
Sbjct: 1011 SSTGTG----TVPTNTVF-----TSTRLPTSETWLSNSSVIPLPLPGVSTIPLTMKPSSS 1061

Query: 994  V-TIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTA--TTTVVANLGGHPQPTQVQFVC 1050
            + TI  +      P   T   S  P  T +T TT T+  TT + + +      T     C
Sbjct: 1062 LPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQMTTQSTLTTTAGTC 1121

Query: 1051 D 1051
            D
Sbjct: 1122 D 1122



 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 151/702 (21%), Positives = 247/702 (35%), Gaps = 94/702 (13%)

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMARE-PGGRSPAFVQ 1210
            ATG L  A  S SQ    +  A S  ++        +  PL  P +A   PG R  A + 
Sbjct: 19   ATGTLSTAT-SISQVPFPRAEAASAVLSNSPHSRDLAGWPLGVPQLASPAPGHRENAPMT 77

Query: 1211 LAP-----LSSKVRLSSP---SIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQ 1262
            L       L S+  L+SP   +    P  + +  V T   T     A    + P    + 
Sbjct: 78   LTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFKVETTPPTVLVYSATTECVYPTSFIIT 137

Query: 1263 GGSPSTTVTVTALEALLCPSATVTQVCSNP--------PCETHETGT---TNTATTSNAG 1311
               P T++ VT  +     S T T V   P           T E GT   T++ +T+ A 
Sbjct: 138  ISHP-TSICVTTTQVAFTSSYTSTPVTQKPVTTVTSTYSMTTTEKGTSAMTSSPSTTTAR 196

Query: 1312 SAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGTTMSV 1371
                V   P   +    T HT  ++T+      P      P G    T   T   TT+  
Sbjct: 197  ETPIVTVTPSSVSATDTTFHTTISSTTRTTERTPL-----PTGSIHTTTSPTPVFTTLKT 251

Query: 1372 SVGALLPDATS--SHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHETGT 1429
            +V +  P  +S  S  TV S    A+ P+ T    +      PT+ + S+ P  + ET T
Sbjct: 252  AVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSS------PTRTILSSTPVLSTETIT 305

Query: 1430 TH-TATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVT 1488
            +  T TT  S + +      + S               TS +   T+ +ST+T + T + 
Sbjct: 306  SGITNTTPLSTLVTTLPTTISRSTP-------------TSETTYPTSPTSTVTDSTTKIA 352

Query: 1489 QSTPVPGP-----SVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQTPEL 1543
             ST + G      S+PP             LP  +   +  T L+  + E+ S S TP  
Sbjct: 353  YSTSMTGTLSTETSLPPTSS---------SLPTTETATTPMTNLVTTTTEISSHS-TPSF 402

Query: 1544 PAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLM 1603
             ++   S+    S+ + ++      T     P  T S  +  +      +     TTT  
Sbjct: 403  SSSTIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTET 462

Query: 1604 VTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMG-----TGEPMDTSEA 1658
             +  TP   +     E  + +A +  +     +      +          T     TS  
Sbjct: 463  TSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFT 522

Query: 1659 AATVTQAELGHLSAEGQEGQATT-IPI---------VLTQQELAALVQQQQLQEAQAQQQ 1708
            ++  T     H +        TT  P+         V T +  + +           +  
Sbjct: 523  SSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETT 582

Query: 1709 HHHLP--TEALAPADSLND--PAIESNCLNELAGTVPSTVALLPSTATESLAPSNTFVAP 1764
             H  P  T ++   ++ ++  P++ S+       T+ STV+   +  T     S T V P
Sbjct: 583  SHSTPGFTSSITTTETTSESTPSLSSS-------TIYSTVSTSTTAITSHFTTSETAVTP 635

Query: 1765 QPVV---VASPAKLQAAATLTEVANGIE-SLGVKPDLPPPPS 1802
             PV    +++     +  TLT  + G   SL    D P  P+
Sbjct: 636  TPVTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPT 677



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 73/371 (19%), Positives = 136/371 (36%), Gaps = 79/371 (21%)

Query: 361  TEKPPPPARVQLVRANTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSV 420
            T+  P P  V     ++++  +     +TA S ++   +  IP+T ++    TP+  PS+
Sbjct: 753  TQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTLQTTPS-TPSL 811

Query: 421  PAN--------------------------------------PPKSPAPAAAAP------- 435
              +                                         SP+ A+  P       
Sbjct: 812  QTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTIH 871

Query: 436  ---------AVQPLTQVGITLLPQAAPAPPTTT-------TIQVLPTVPGSSISVPTAAR 479
                     + + +    IT  P  + +  T+T       T  +    P S IS+P+   
Sbjct: 872  SVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLPS--- 928

Query: 480  TQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVT-VTSLPAGVRMV-----VPTQSAQ 533
            T   P  + +T   A+   P V M P+++A   P T +T  P    MV     +  Q+  
Sbjct: 929  TTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTL 988

Query: 534  GTVIGSSPQM----SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAV----TPG 585
             T + +S  M    S ++  A+++  T  +P ++  T   +P   T +   +V     PG
Sbjct: 989  TTYMDTSSMMPESESSISPNASSSTGTGTVPTNTVFTSTRLPTSETWLSNSSVIPLPLPG 1048

Query: 586  TTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQ 645
             +T+P T+K +SS   +   +++    +     TS +    T T   +T  ++  +T   
Sbjct: 1049 VSTIPLTMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTPTTLTSRRTTRITSQM 1108

Query: 646  QAQVVTTVVGG 656
              Q   T   G
Sbjct: 1109 TTQSTLTTTAG 1119


>gi|16945972 kelch domain containing 3 [Homo sapiens]
          Length = 382

 Score =  114 bits (284), Expect = 1e-24
 Identities = 84/269 (31%), Positives = 128/269 (47%), Gaps = 24/269 (8%)

Query: 15  LQPRWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGN--EGIVDELHVYNTATNQWFIP 72
           L P    + G +  VP  R+GH  V I + ++++GG N  EG  + L+ ++  T++WF P
Sbjct: 59  LPPVKSAIRGQAPVVPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTP 118

Query: 73  AVRGDIPPGCAAYGFVCDGTRLLVFGGMVEYGK-YSNDLYELQASRWEWKRLKAKTPKNG 131
            V G +P     +     G  + +FGG  +    +SND+++L  S   W  +  K    G
Sbjct: 119 RVSGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTK----G 174

Query: 132 PPPCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAW-DIP 190
            P   R  HS +++G+  Y+FGG A+      +N   Y N + + + R      AW D P
Sbjct: 175 SPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTR----TEAWLDCP 230

Query: 191 ITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLG----DLWTLDIDTLTWNKPS 246
            T  VLP  R SH+A  Y        +L I+GG +  RL     DLW  +  + TW K  
Sbjct: 231 PT-PVLPEGRRSHSAFGYN------GELYIFGGYNA-RLNRHFHDLWKFNPVSFTWKKIE 282

Query: 247 LSGVAPLPRSLHSATTIGNKMYVFGGWVP 275
             G  P PR       +G+K+ +FGG  P
Sbjct: 283 PKGKGPCPRRRQCCCIVGDKIVLFGGTSP 311



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 80/281 (28%), Positives = 106/281 (37%), Gaps = 42/281 (14%)

Query: 88  VCDGTRLLVFGGMVEYGKYSN----DLYELQASRWEWKRLK-AKTPKNGPPPCP---RLG 139
           V  G R+  FGG      Y      D++   A    W +L   K+   G  P     R G
Sbjct: 20  VAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRGQAPVVPYMRYG 79

Query: 140 HSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPP 199
           HS  L+ +   L+GG  ND+E          N LY  ++        W  P   G +P  
Sbjct: 80  HSTVLIDDTVLLWGG-RNDTEGA-------CNVLYAFDVNTHK----WFTPRVSGTVPGA 127

Query: 200 RESHTAVVYTEKDNKKSKLVIYGG---MSGCRLGDLWTLDIDTLTWNKPSLSGVAPLPRS 256
           R+ H+A V  +       + I+GG    + C   D+  LD  T+TW      G     R 
Sbjct: 128 RDGHSACVLGKI------MYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWRD 181

Query: 257 LHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLED 316
            HSAT +G+ MYVFGG       D     H       N +   +  T AW   L      
Sbjct: 182 FHSATMLGSHMYVFGG-----RADRFGPFHSNNEIYCNRIRVFDTRTEAW---LDCPPTP 233

Query: 317 NIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLW 357
            +P  R  H A   N  LYI+    GY    N      DLW
Sbjct: 234 VLPEGRRSHSAFGYNGELYIFG---GYNARLNRHF--HDLW 269



 Score = 65.1 bits (157), Expect = 7e-10
 Identities = 63/248 (25%), Positives = 106/248 (42%), Gaps = 45/248 (18%)

Query: 137 RLGHSFSLVGNKCYLFGGLAN--DSEDPKNNIPRYLN--DLYILELRPGSGVVAWDIPIT 192
           R+ H+   VG++ Y FGG  +  D E  +       N   L   +L P    +    P  
Sbjct: 14  RVNHAAVAVGHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRGQAP-- 71

Query: 193 YGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMS----GCRLGDLWTLDIDTLTWNKPSLS 248
             V+P  R  H+ V+  +       ++++GG +     C +  L+  D++T  W  P +S
Sbjct: 72  --VVPYMRYGHSTVLIDD------TVLLWGGRNDTEGACNV--LYAFDVNTHKWFTPRVS 121

Query: 249 GVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKC-TNTLACLNLDTMAWE 307
           G  P  R  HSA  +G  MY+FGG             +E++  C +N +  L+  TM W 
Sbjct: 122 GTVPGARDGHSACVLGKIMYIFGG-------------YEQQADCFSNDIHKLDTSTMTWT 168

Query: 308 TILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAW--NNQVCCKDLWYLET---- 361
            I     + +  R R  H A  + + +Y++ GR      +  NN++ C  +   +T    
Sbjct: 169 LI---CTKGSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEA 225

Query: 362 --EKPPPP 367
             + PP P
Sbjct: 226 WLDCPPTP 233



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 44/167 (26%), Positives = 72/167 (43%), Gaps = 17/167 (10%)

Query: 27  GPVPRPRHGHRAVAIKELIVVFGG----------GNEGIVDELHVYNTATNQWFIPAVRG 76
           G   R R  H A  +   + VFGG           NE   + + V++T T  W       
Sbjct: 174 GSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLDCPPTP 233

Query: 77  DIPPGCAAYGFVCDGTRLLVFGGM-VEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPC 135
            +P G  ++        L +FGG      ++ +DL++     + WK+++ K    G  PC
Sbjct: 234 VLPEGRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPK----GKGPC 289

Query: 136 PRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYL--NDLYILELRP 180
           PR      +VG+K  LFGG +   E+   +    +  +DL+IL+  P
Sbjct: 290 PRRRQCCCIVGDKIVLFGGTSPSPEEGLGDEFDLIDHSDLHILDFSP 336


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score =  112 bits (280), Expect = 4e-24
 Identities = 307/1365 (22%), Positives = 486/1365 (35%), Gaps = 230/1365 (16%)

Query: 406  AATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLP 465
            ++T     P    S P++   SPAP+    A      V ++    ++P+   TT      
Sbjct: 331  SSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAF-----VKLSTTYHSSPSSTPTTHFSASS 385

Query: 466  TVPGSSI------SVPTAARTQGVPAVLKVTG--------------------PQATTGTP 499
            T  G S       S P A  T   PA    +G                    P+++T T 
Sbjct: 386  TTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESST-TS 444

Query: 500  LVTMRPASQAGKAPVTVTSLPAGVRMVVPTQ------SAQGTVIGSSPQMSGMAALAAA- 552
              +   A+  G    T +S P+    +  T       S + T    S  +SG +  + A 
Sbjct: 445  GHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEESKAS 504

Query: 553  -----AAATQKIPPSSAPTVL-----SVPAGTTIVKTMAVTPGTTTLPATVKVA----SS 598
                 A AT  +P  S P+VL       P  +  ++T A+ PG+TT P   + +    SS
Sbjct: 505  HSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTAL-PGSTTKPGLSEKSTTFYSS 563

Query: 599  PVMVSNPATRMLKTAAAQVGTSVSSATNTSTRP--IITVHKSGTVTVAQQAQVVTTVVGG 656
            P    +P T  L  +    G S  S T+ S RP    T    G+ T+   +Q  T     
Sbjct: 564  P---RSPDTTHLPASMTSSGVSEESTTSHS-RPGSTHTTAFPGSTTMPGLSQESTASHSS 619

Query: 657  VTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPL 716
               T T + SP     GS   S+LG   +   ++P  T       +T   + +++   P+
Sbjct: 620  PGPTDTTL-SP-----GSTTASSLGPEYTTFHSRPGSTETTLLPDNT-TASGLLEASMPV 672

Query: 717  ------------PAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPG 764
                        PAG+     T+  G+ TT  +   ++     P     + V PSTT  G
Sbjct: 673  HSSTRSPHTTLSPAGS-----TTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHG 727

Query: 765  TTTIIKTIPMSAIITQAG----ATGVTSSPGIKSPITIITTKVMTSGTG----------- 809
            + + I T  +SA  T +G    +T   SSPG    +    +   TSG G           
Sbjct: 728  SPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDT-TSGRGEESTTSHSSTT 786

Query: 810  -----APAKIITAVPKIATGHGQQGVTQVV-LKGAPGQPGTILRTVPMGGVRLVTPVTVS 863
                 AP+     V +  + H   G T       +    G    ++     +  T   V 
Sbjct: 787  HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVL 846

Query: 864  AVKPAVTTLVVKGTTGVTTLGTVTGTV---STSLAGAGGHSTS--ASLATPITTLGTIAT 918
              +   + L+ + TT   + G++  T    ST+  G    ST+  +S  +P TTL   +T
Sbjct: 847  PARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPAST 906

Query: 919  LSSQVINPTAITVSAAQTTLTAA--GGLTTP-------TITMQPVSQPTQVTLITAPSGV 969
             SS V   +  + S   +T T A     TTP       T    P S  T +   +  + +
Sbjct: 907  TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXL 966

Query: 970  EAQPVHDLPVSILASPTTEQPTATVTIADSGQGDV---QPGTVTLVCSNPPCETHETGTT 1026
              +P    P+S  ++ TT  P +T T   S +       P +     S  P  T  +G +
Sbjct: 967  VGEPTTS-PISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS--PASTTSSGVS 1023

Query: 1027 NTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHET- 1085
              +TT+       H +P                 T T      + +   S     +H + 
Sbjct: 1024 EESTTS-------HSRPGS---------------THTTAFPGSTTMPGVSQESTASHSSP 1061

Query: 1086 GTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPA 1145
            G+T+T  +  S  A   G   P   T  +G  +T TT +                     
Sbjct: 1062 GSTDTTLSPRSTTASSLG---PESTTFHSGPGSTETTLLPD------------------- 1099

Query: 1146 VIRISVATGALEAAQGSKSQC-QTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPGGR 1204
                + A+G LEA+    S     R T + + + T         + P    +M   P   
Sbjct: 1100 ---NTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTT 1156

Query: 1205 SPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGG 1264
            S AFV+L+  S      SPS   +P    S + +T   +  S       +AP        
Sbjct: 1157 S-AFVELSTTSH----GSPS--SIPTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPAR 1209

Query: 1265 SPSTTVTVTALEALLCPSATVT------QVCSNPPCETHETGTTNTATTSNAGSAQRVCS 1318
            S ++ +   +      P +T T         S    E+  + ++ T T S+  S      
Sbjct: 1210 STTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALV 1269

Query: 1319 NPPCETHET----GTTHTATTATSNGGTGQPEGGQQPPAGR---PCETHQTTS----TGT 1367
              P   H +     TTH   ++T++G + +       P      P   H TTS      T
Sbjct: 1270 EEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAEST 1329

Query: 1368 TMSVSVGALLPDATSSHRT--VESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETH 1425
            T  +S G++     S+  T  + +   +  + S +P   T   A   +  +   P     
Sbjct: 1330 TFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQ-TLSPASMTSSSISGEPTSLYS 1388

Query: 1426 ETGTTHT----ATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAIT-TTVSSTL 1480
            +  +THT    A+T TS +S  Q+     S  G  E+T       TSS A   TT  S  
Sbjct: 1389 QAESTHTTAFPASTTTSGLS--QESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQP 1446

Query: 1481 TRAVTTVT-QSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAEVLSASQ 1539
              A++TV+  ST VPG S         SPG  +         S S  +   S +      
Sbjct: 1447 GSALSTVSPASTTVPGLS-EESTTFYSSPGSTE-----TTAFSHSNTMSIHSQQSTPFPD 1500

Query: 1540 TP-----ELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAE 1594
            +P      LPA +  +  G+ S+   S+  A   T    P P   +  D +  P      
Sbjct: 1501 SPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTT----PLPARSTASDLVGEPTTFYIS 1556

Query: 1595 AQAGTTTLM-----VTGLTPEELAVTAAAEAAAQAAATEEAQALA 1634
                 TTL       +GLT E      +    +   +TE  + LA
Sbjct: 1557 PSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLETLA 1601



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 269/1325 (20%), Positives = 460/1325 (34%), Gaps = 162/1325 (12%)

Query: 435  PAVQPLTQVGI--TLLPQA---APAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKV 489
            P   P+T   +  T LP +   A     +TT    P  P  ++S P    + GV      
Sbjct: 173  PKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLS-PARTTSSGVSEKSTT 231

Query: 490  T----GPQATTGTPLVTMRPASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSS--PQM 543
            +    GP  T   P  T  P     +      S+P        T  + GT   SS  P+ 
Sbjct: 232  SHSRPGPTHTIAFPDSTTMPG--VSQESTASHSIPGST----DTTLSPGTTTPSSLGPES 285

Query: 544  SGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVS 603
            +   + +     T ++P ++  T   +   +T V +   +P TT  PA     SS     
Sbjct: 286  TTFHS-SPGYTKTTRLPDNT--TTSGLLEASTPVHSSTGSPHTTLSPA-----SSTTHEG 337

Query: 604  NPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITL 663
             P T     ++     + S  T+   +   T H S + T        +T +G   ++  +
Sbjct: 338  EPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPV 397

Query: 664  VKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILK 723
              SP+                +   T P   SA +G             + P    T+  
Sbjct: 398  HSSPV----------------ATATTPPPARSATSGHVEESTAYH----RSPGSTQTMHF 437

Query: 724  LVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGA 783
              +S     +    T   S   TK +    ++    T+   +    +T       T +G 
Sbjct: 438  PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 497

Query: 784  TGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPK-IATGHGQQGVTQVVLKGAPGQP 842
            +   S     SP  + TT V+ +G+     +  + P  I++G     +    L G+  +P
Sbjct: 498  S-EESKASHSSPDAMATT-VLPAGSTPSVLVGDSTPSPISSG----SMETTALPGSTTKP 551

Query: 843  GTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHST 902
            G   ++         T    S   P  T L       +T+ G    + ++       H+T
Sbjct: 552  GLSEKS---------TTFYSSPRSPDTTHL----PASMTSSGVSEESTTSHSRPGSTHTT 598

Query: 903  SASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTL 962
            +   +T +  L   +T S     PT  T+S   TT ++ G   T T   +P S  T+ TL
Sbjct: 599  AFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYT-TFHSRPGS--TETTL 655

Query: 963  I---TAPSGV--EAQPVHDLPVSILASPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPP 1017
            +   T  SG+   + PVH          +T  P  T++ A S     + G  T   S P 
Sbjct: 656  LPDNTTASGLLEASMPVHS---------STRSPHTTLSPAGS---TTRQGESTTFHSWPS 703

Query: 1018 CETHETGTTNTATTTVVANLGGHPQPTQV--QFVCDRQEAAASLVTSTVGQQNGSVVRVC 1075
                      T +  V  +   H  P+ +    +  R   +  +  ST    +    +  
Sbjct: 704  SNDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTM 763

Query: 1076 SNPPCET-----HETGTTNTATTATSNMA------------GQHGCSNPPCETHETGTTN 1118
              P  +T      E+ T++++TT T + A              H        TH   ++ 
Sbjct: 764  HFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSST 823

Query: 1119 TATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSATSTTM 1178
            T+  +  S+ ++  +DA        PA    SV  G    +  S    +T     ++TT 
Sbjct: 824  TSGRSEESIASHSSQDATGTIV--LPARSTNSVLLGESTTSPISSGSMETTALPGSTTTP 881

Query: 1179 TVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVS 1238
             +        + P   P+    P   + + V     +S  R  S      P    +  +S
Sbjct: 882  GLSERSTTFHSSP-RSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS 940

Query: 1239 TAAMT-RSSVGAGEPRMAPVCES--LQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCE 1295
              + T  SS G+ +  + P   +  L G   ++ ++  + E    P +T T   S     
Sbjct: 941  RHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 1000

Query: 1296 THETGTTNTATTSNAGSAQRVCSNPPCETH-ETGTTHTATTATSNGGTGQPEGGQQPPAG 1354
             + +  +   T S A +     S     +H   G+THT       G T  P   Q+  A 
Sbjct: 1001 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP---GSTTMPGVSQESTAS 1057

Query: 1355 R--PCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTP-----QAGTAL 1407
               P  T  T S  +T + S+G   P++T+ H +     E    P  T      +A T +
Sbjct: 1058 HSSPGSTDTTLSPRSTTASSLG---PESTTFH-SGPGSTETTLLPDNTTASGLLEASTPV 1113

Query: 1408 LAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVEST---QGDSV 1464
             +   + R   +P   T   G + T  +  S+  +   PP   S   E+ +T      S+
Sbjct: 1114 HSSTGSPRTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSI 1173

Query: 1465 NITSSSAITTTV----SSTLTRAVTTVTQSTPVPGPS-----VPPPEELQVSPGPRQQLP 1515
              T  SA +TT      ST   +      +TP P  S     V        SPG  Q + 
Sbjct: 1174 PTTHFSASSTTFGRSEESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTM- 1232

Query: 1516 PRQLLQSASTALMGESAEVLSASQTPEL--PAAVDLSSTGEPSSGQESAGSAVVATVVVQ 1573
                 +S++ +   E +    +S T  +  P +   +   EP+S   S GS         
Sbjct: 1233 --HFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPES 1290

Query: 1574 PPPPTQSEVDQLS-----------LPQELMAEAQAGTTTLMVTGLTPEELAVTAAAEA-- 1620
                 +SE    S           LP       +   +T     ++P  +  T A+ A  
Sbjct: 1291 STTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFY--ISPGSMETTLASTATT 1348

Query: 1621 ---AAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDT-SEAAATVTQAELGHLSAEGQE 1676
               +A++     +     Q +  A+  +   +GEP    S+A +T T A     +  G  
Sbjct: 1349 PGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLS 1408

Query: 1677 GQATT 1681
             ++TT
Sbjct: 1409 QESTT 1413



 Score = 85.1 bits (209), Expect = 6e-16
 Identities = 266/1278 (20%), Positives = 433/1278 (33%), Gaps = 157/1278 (12%)

Query: 594  KVASSPVMVSNPATRMLKTAAAQ---------VGTSVSSATNTSTRPIITVHKSGTVTVA 644
            +V+SSP +    AT+  +T              G++V+++   +T    T   S   T  
Sbjct: 54   EVSSSPDVSELTATKHEETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTF 113

Query: 645  QQAQVVTTVVGGVTKTITLVKSPI-SVPGGSALISNLGKVMSVVQTKPVQ--TSAVTGQA 701
                V  T + G T T   + S   S     + +S+ G   +     P    TS   G+ 
Sbjct: 114  SDYGVSVTFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEP 173

Query: 702  STGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTT 761
             T P+T        LP  T          K TT  ++ ++      P     S VS  +T
Sbjct: 174  KTSPITSASMETTALPGST---TTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKST 230

Query: 762  ----KPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITA 817
                +PG T  I      A        GV+        I   T   ++ GT  P+ +   
Sbjct: 231  TSHSRPGPTHTI------AFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSL--- 281

Query: 818  VPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGT 877
             P+  T H   G T+               T   G +   TPV  S   P  T      T
Sbjct: 282  GPESTTFHSSPGYTKTTRLPD--------NTTTSGLLEASTPVHSSTGSPHTTLSPASST 333

Query: 878  T---GVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAA 934
            T     TT  +   +  TS A +G  S    L+T         T  S   +      SA+
Sbjct: 334  THEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLST---------TYHSSPSSTPTTHFSAS 384

Query: 935  QTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSG--VEAQPVHDLPVSILASPTTEQPTA 992
             TTL      +TP  +    +  T     +A SG   E+   H  P S   + T   P +
Sbjct: 385  STTL-GHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGS---TQTMHFPES 440

Query: 993  TVTIADSGQGDVQPGTVTLVCSNPPCET---------HETGTTNTATTTVVANLGGHPQP 1043
            + T   S +     G+ T   S+ P  T            G+T T      + + G  + 
Sbjct: 441  STTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGRSEE 500

Query: 1044 TQVQFVCDRQEA-----AASLVTSTVGQQNGSVVRVCSNP----PCETHETGTTNTATTA 1094
            ++         A     A S  +  VG    S +   S      P  T + G +  +TT 
Sbjct: 501  SKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTF 560

Query: 1095 TSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQR-----------DARRACAAGT 1143
             S+       ++ P     +G +  +TT+ S  G+ H                   +  +
Sbjct: 561  YSSPRSP-DTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSS 619

Query: 1144 PAVIRISVATGALEAAQ-GSKSQCQTRQTSATSTTMTVMATGAPCSAGPLLGPSMAREPG 1202
            P     +++ G+  A+  G +      +  +T TT+    T    +A  LL  SM     
Sbjct: 620  PGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNT----TASGLLEASMPVHSS 675

Query: 1203 GRSPAFVQLAPLSSKVRL-SSPSIKDLPAGRHSH----AVSTAAMTRSSVGAGEPRMAPV 1257
             RSP    L+P  S  R   S +    P+   +       ++A +  S+   G P   P 
Sbjct: 676  TRSP-HTTLSPAGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVEPSTTSHGSPSSIPT 734

Query: 1258 CESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCET-----HETGTTNTATTSNAGS 1312
                   + STT  +         S   TQ    P  +T      E+ T++++TT    S
Sbjct: 735  THI---SARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS 791

Query: 1313 AQRVCS---NPPCETH----ETGTTHTATTATSNGGTGQ--PEGGQQPPAGRPCETHQTT 1363
            A    S     P   H     T TTH   ++T++G + +       Q   G      ++T
Sbjct: 792  APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARST 851

Query: 1364 ST-----GTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPT--QRV 1416
            ++      TT  +S G++   A     T     E +     +P++    L+P  T    V
Sbjct: 852  NSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGV 911

Query: 1417 CSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTT- 1475
                       G+THT     S  +      P  S       +   S + T   A TTT 
Sbjct: 912  SEESTTSHSRPGSTHTTAFPDSTTT------PGLSRHSTTSHSSPGSTDTTLLPASTTTX 965

Query: 1476 -VSSTLTRAVTT-VTQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAE 1533
             V    T  +++  T++T +PG +       + +        P   L  AST   G S E
Sbjct: 966  LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 1025

Query: 1534 VLS------ASQTPELPAAVDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSL 1587
              +      ++ T   P +  +    + S+   S+  +   T  + P   T S +     
Sbjct: 1026 STTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTT--LSPRSTTASSLG---- 1079

Query: 1588 PQELMAEAQAGTTTLMVTGLTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVM 1647
            P+     +  G+T    T L P+    +   EA+    ++  +    +       +Q   
Sbjct: 1080 PESTTFHSGPGSTE---TTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTTRQGES 1136

Query: 1648 GTGE----PMDTSEAAATVTQA--ELGHLSAEGQEGQATTIPIVLTQQELAALVQQQQLQ 1701
             T +      DT  A  T T A  EL   S     G  ++IP   T    A+     + +
Sbjct: 1137 TTFQSWPSSKDTMPAPPTTTSAFVELSTTS----HGSPSSIP---TTHFSASSTTFGRSE 1189

Query: 1702 EAQAQQQHHHLPTEALAPADSLNDPAI-ESNCLNELAGTVPSTVALLPSTATESLAPSNT 1760
            E+         P    +PA S     + ES   +   G+  +      STA+     S T
Sbjct: 1190 ESTTVHSSPVAPATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1249

Query: 1761 FVAPQPVVVASPAKLQAA 1778
              +     ++SP    +A
Sbjct: 1250 SHSSTTHTISSPPSTTSA 1267


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score =  106 bits (264), Expect = 3e-22
 Identities = 141/560 (25%), Positives = 192/560 (34%), Gaps = 100/560 (17%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQ 462
            P T  T  +PTP P     +    +P P      V P      T  P   P   TTTT+ 
Sbjct: 1315 PITTTTTVTPTPTPT----STQSTTPTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVT 1369

Query: 463  VLPTVPGSSISVPT-AARTQGVPAVLKVTGPQATTGTPLVTMRPASQAGKAPVTVTSLPA 521
              PT  G+     T    T  V      TG Q  T TP+ T           VT T  P 
Sbjct: 1370 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITT--------TTTVTPTPTPT 1421

Query: 522  GVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTM 580
            G +    T     T +  +P  +G  A    A   T  + P+  PT    P  T I  T 
Sbjct: 1422 GTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTT 1481

Query: 581  AVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGT 640
             VTP  T           P     P    + T      T   + T T T   IT      
Sbjct: 1482 TVTPTPT-----------PTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPIT------ 1524

Query: 641  VTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQ 700
                      TT     T T T  ++P   P           + +     P  T   T  
Sbjct: 1525 ----------TTTTVTPTPTPTGTQTPTPTP-----------ISTTTTVTPTPTPTGTQT 1563

Query: 701  ASTGPVTQIIQ-TKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPS 759
             +T P+T     T  P P GT           PTT++ TT  +   T PT        P+
Sbjct: 1564 PTTTPITTTTTVTPTPTPTGT---------QTPTTVLITTTTTMTPT-PT--------PT 1605

Query: 760  TTKPGTTT-IIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818
            +TK  T T I  T  ++A  T  G    T  P I +  T+  T   T+G+  P    +  
Sbjct: 1606 STKSTTVTPITTTTTVTATPTPTGTQTPTMIP-ISTTTTVTPTPTPTTGSTGPPTHTSTA 1664

Query: 819  PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT 878
            P          + ++     P +  T   +         +   +S + PA+        T
Sbjct: 1665 P----------IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE------MT 1708

Query: 879  GVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTL 938
                  T T   +TS    GGH+ S   +T  +  GT  T  +   + +A T S  QTT 
Sbjct: 1709 STAPPSTPTAPTTTS----GGHTLSPPPSTTTSPPGT-PTRGTTTGSSSAPTPSTVQTTT 1763

Query: 939  TAAGGLTTPTITMQPVSQPT 958
            T+A    TPT T  P+S P+
Sbjct: 1764 TSA---WTPTPT--PLSTPS 1778



 Score =  100 bits (250), Expect = 1e-20
 Identities = 118/470 (25%), Positives = 164/470 (34%), Gaps = 49/470 (10%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSP-------APAAAAPAVQPLTQVGITLLPQAAPAP 455
            P    T T+ TP P P+    P  +P        P       Q  T   IT      P P
Sbjct: 1336 PTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1395

Query: 456  -----------PTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMR 504
                       P TTT  V PT   +    PT   T  +     VT     TGT   T  
Sbjct: 1396 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPTPTGTQAPT-- 1450

Query: 505  PASQAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSG-MAALAAAAAATQKIPPSS 563
            P +    + VT T  P G +    T     T +  +P  +G       A   T  + P+ 
Sbjct: 1451 PTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTP 1510

Query: 564  APTVLSVPAGTTIVKTMAVTP-----GTTT-------LPATVKVASSPVMVSNPATRMLK 611
             PT    P  T I  T  VTP     GT T          TV    +P     P T  + 
Sbjct: 1511 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPIT 1570

Query: 612  TAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVP 671
            T      T   + T T T  +IT   + T T    +   TTV   +T T T+  +P    
Sbjct: 1571 TTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVT-PITTTTTVTATPTPTG 1629

Query: 672  GGSALISNLGKVMSVVQTKPVQTSAVTG---QASTGPVTQIIQTKGPLPAGTILKLVTSA 728
              +  +  +    +V  T P  T+  TG     ST P+ ++  +  P  + T     + +
Sbjct: 1630 TQTPTMIPISTTTTVTPT-PTPTTGSTGPPTHTSTAPIAELTTSNPPPESST--PQTSRS 1686

Query: 729  DGKPTTIITTTQASGAGTKPTILGISSVSPST-TKPGTTTIIKTI--PMSAIITQAGATG 785
               P T  TT  ++     P I   S+  PST T P TT+   T+  P S   +  G   
Sbjct: 1687 TSSPLTESTTLLST---LPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPT 1743

Query: 786  VTSSPGIKSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVL 835
              ++ G  S  T  T +  T+    P     + P I    G +     VL
Sbjct: 1744 RGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL 1793



 Score = 95.5 bits (236), Expect = 5e-19
 Identities = 128/512 (25%), Positives = 181/512 (35%), Gaps = 50/512 (9%)

Query: 689  TKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKP 748
            T+P   +  T +  T        T  P P  T  +  T     PT I TTT  +     P
Sbjct: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTT-----PTPITTTTTVT-----P 1347

Query: 749  TILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMT--- 805
            T     + +P+TT   TTT +   P     T  G    T++P I +  T+  T   T   
Sbjct: 1348 TPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTP-ITTTTTVTPTPTPTGTQ 1401

Query: 806  SGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAV 865
            + T  P    T V    T  G Q  T   +        T+  T    G +  TP  ++  
Sbjct: 1402 TPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTT----TVTPTPTPTGTQAPTPTAITTT 1457

Query: 866  KPAVTTLVVKGT-TGVTTLGTVTGTVSTSLAGAGGHS-TSASLATPITTLGTIATLSSQV 923
                 T    GT T  TT  T T TV+ +    G  + T  ++ T  T   T     +Q 
Sbjct: 1458 STVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQT 1517

Query: 924  INPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILA 983
               T IT +   T      G  TPT T  P+S  T VT    P+G +         + + 
Sbjct: 1518 PTSTPITTTTTVTPTPTPTGTQTPTPT--PISTTTTVTPTPTPTGTQTP-----TTTPIT 1570

Query: 984  SPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQP 1043
            + TT  PT T T   +    +   T T+  +  P  T  T  T   TTT V      P P
Sbjct: 1571 TTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVT---ATPTP 1627

Query: 1044 TQVQFVCDRQEAAASLVTSTVGQQNGS------------VVRVCSNPPCETHETGTTNTA 1091
            T  Q       +  + VT T     GS                 SNPP E+    T+ + 
Sbjct: 1628 TGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 1687

Query: 1092 TTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISV 1151
            ++  +          P  E   T   +T  TA ++    H      +     P       
Sbjct: 1688 SSPLTESTTLLSTLPPAIEMTSTAPPST-PTAPTTTSGGHTLSPPPSTTTSPPGTPTRGT 1746

Query: 1152 ATGALEAAQGSKSQCQTRQTSATSTTMTVMAT 1183
             TG+  A   + S  QT  TSA + T T ++T
Sbjct: 1747 TTGSSSAP--TPSTVQTTTTSAWTPTPTPLST 1776



 Score = 92.4 bits (228), Expect = 4e-18
 Identities = 136/551 (24%), Positives = 193/551 (35%), Gaps = 97/551 (17%)

Query: 588  TLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQA 647
            T P T+   ++      P T           TS  S T T   PI T     T TV    
Sbjct: 1298 TQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPT---PITT-----TTTVTP-- 1347

Query: 648  QVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGPVT 707
                      T T T  ++P + P           + +     P  T   T   +T P+T
Sbjct: 1348 ----------TPTPTGTQTPTTTP-----------ITTTTTVTPTPTPTGTQTPTTTPIT 1386

Query: 708  QIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTT 767
                T  P P  T  +  TS     TT +T T        PT   I++ +  T  P  T 
Sbjct: 1387 -TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1445

Query: 768  IIKTIPMSAIITQAGATGVTSSPGIKSPITI-ITTKVMTSGTGAPAKIITAVPKIATGHG 826
                 P +AI T +  T   +  G ++P T  ITT    + T  P    T  P   T   
Sbjct: 1446 TQAPTP-TAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAIT--- 1501

Query: 827  QQGVTQVVLKGAPGQPGTILRT-VPMGGVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGT 885
                T   +   P   GT   T  P+     VTP          T   +  TT VT   T
Sbjct: 1502 ----TTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPT 1557

Query: 886  VTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQ--VINPTAITVSAAQTTLTAAGG 943
             TGT + +              TPITT  T+    +      PT + ++   T       
Sbjct: 1558 PTGTQTPT-------------TTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMTPTPTP 1604

Query: 944  LTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQGD 1003
             +T + T+ P++  T VT    P+G +   +  +P+S   + TT  PT T T   +G   
Sbjct: 1605 TSTKSTTVTPITTTTTVTATPTPTGTQTPTM--IPIS---TTTTVTPTPTPTTGSTG--- 1656

Query: 1004 VQPGTVT-------LVCSNPPCE------THETGTTNTATTTVVANLGGHPQPTQVQFVC 1050
              P T T       L  SNPP E      +  T +  T +TT+++ L     P  ++   
Sbjct: 1657 --PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTL-----PPAIEMTS 1709

Query: 1051 DRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCE 1110
                +  +  T+T G          S PP  T     T T  T T +       S P   
Sbjct: 1710 TAPPSTPTAPTTTSGG------HTLSPPPSTTTSPPGTPTRGTTTGS------SSAPTPS 1757

Query: 1111 THETGTTNTAT 1121
            T +T TT+  T
Sbjct: 1758 TVQTTTTSAWT 1768



 Score = 92.0 bits (227), Expect = 5e-18
 Identities = 153/686 (22%), Positives = 230/686 (33%), Gaps = 94/686 (13%)

Query: 900  HSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTT------------- 946
            H    S+ T  +TL T  T++     PT  T +   TT T++  L+T             
Sbjct: 1153 HFNICSITTRPSTLTTFTTITLPT-TPTTFTTTTTTTTPTSSTVLSTTPKLCCLWSDWIN 1211

Query: 947  ---PTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTIADSGQG- 1002
               P+       + T   +  AP  +E + V D  +S+       Q    V++    +  
Sbjct: 1212 EDHPSSGSDDGDRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQLVCDVSVGLICKNE 1271

Query: 1003 DVQPGTVTLV--CSNPP-----CETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEA 1055
            D +PG V  +  C N       CE     TT T TTT       +P PT +         
Sbjct: 1272 DQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTE------NPTPTPITTTTTVTPT 1325

Query: 1056 AASLVT-STVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHET 1114
                 T ST      +   V   P     +T TT   TT T+              T   
Sbjct: 1326 PTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1385

Query: 1115 GTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQTSAT 1174
             TT T T   +  G              TP    I+  T        + +Q  T  T+  
Sbjct: 1386 TTTTTVTPTPTPTGTQ------------TPTSTPITTTTTVTPTPTPTGTQTPT--TTPI 1431

Query: 1175 STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHS 1234
            +TT TV  T  P               G ++P    +   S+     +P+    P     
Sbjct: 1432 TTTTTVTPTPTPT--------------GTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPI 1477

Query: 1235 HAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPC 1294
               +T   T +  G   P    +         +TT TVT       P+ T TQ  ++ P 
Sbjct: 1478 TTTTTVTPTPTPTGTQTPTPTAI---------TTTTTVTPT-----PTPTGTQTPTSTPI 1523

Query: 1295 ETHETGT-------TNTATTSNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEG 1347
             T  T T       T T T +   +   V   P     +T TT   TT T+   T  P G
Sbjct: 1524 TTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 1583

Query: 1348 GQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTAL 1407
             Q P       T   T T T  S     + P  T++  T          P++ P + T  
Sbjct: 1584 TQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTT 1643

Query: 1408 LAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNIT 1467
            + P PT    S  P        THT+T   + ++++  PP +++ Q    ++   + + T
Sbjct: 1644 VTPTPTPTTGSTGP-------PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTT 1696

Query: 1468 SSSAITTTVSSTLTRAVTTVTQSTPVPGPSV--PPPEELQVSPGPRQQLPPRQLLQSAST 1525
              S +   +  T T   +T T  T   G     PPP      PG     P R     +S+
Sbjct: 1697 LLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG----TPTRGTTTGSSS 1752

Query: 1526 ALMGESAEVLSASQTPELPAAVDLSS 1551
            A    + +  + S     P  +   S
Sbjct: 1753 APTPSTVQTTTTSAWTPTPTPLSTPS 1778



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 200/844 (23%), Positives = 281/844 (33%), Gaps = 155/844 (18%)

Query: 717  PAGTILKL--VTSADGKPTTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPM 774
            P GT+ K   + S   +P+T+ T T      T PT     + + +TT P ++T++ T P 
Sbjct: 1146 PNGTVEKHFNICSITTRPSTLTTFTTI----TLPTTPTTFTTTTTTTTPTSSTVLSTTPK 1201

Query: 775  SAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKI---ITAVPKIATGHGQQGVT 831
               +          S G          +      GAP  I       P ++     Q V 
Sbjct: 1202 LCCLWSDWINEDHPSSGSDDG----DRETFDGVCGAPEDIECRSVKDPHLSLEQLGQKVQ 1257

Query: 832  QV-------VLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGT---TGVT 881
             V       + K    +PG ++         +         +P   T         T +T
Sbjct: 1258 LVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPTPIT 1317

Query: 882  TLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAA 941
            T  TVT T + +       ST ++  TPITT  T+         PT  T +  QT  T  
Sbjct: 1318 TTTTVTPTPTPT-------STQSTTPTPITTTTTVT--------PTP-TPTGTQTPTTTP 1361

Query: 942  GGLTTPTITMQPVSQPT-----QVTLITAPSGVEAQPVHDLPVSILASPTTEQPTATVTI 996
                T T T+ P   PT       T IT  + V   P      +  ++P T   T T T 
Sbjct: 1362 ---ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTP 1418

Query: 997  ADSG--QGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQE 1054
              +G       P T T   +  P  T     T TA TT  + +   P PT  Q       
Sbjct: 1419 TPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITT-TSTVTPTPTPTGTQTPTTTPI 1477

Query: 1055 AAASLVTST---VGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCET 1111
               + VT T    G Q  +   +            TT T  T T    G    ++ P   
Sbjct: 1478 TTTTTVTPTPTPTGTQTPTPTAI------------TTTTTVTPTPTPTGTQTPTSTPIT- 1524

Query: 1112 HETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEAAQGSKSQCQTRQT 1171
                TT T T   +  G              TP    IS  T        + +  QT  T
Sbjct: 1525 ----TTTTVTPTPTPTGTQ------------TPTPTPISTTTTVTPTP--TPTGTQTPTT 1566

Query: 1172 SATSTTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAG 1231
            +  +TT TV  T  P               G ++P  V +   ++     +P+       
Sbjct: 1567 TPITTTTTVTPTPTP--------------TGTQTPTTVLITTTTTMTPTPTPTSTKSTTV 1612

Query: 1232 RHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSN 1291
                  +T   T +  G   P M P+         STT TVT       P+ T T   + 
Sbjct: 1613 TPITTTTTVTATPTPTGTQTPTMIPI---------STTTTVT-------PTPTPTTGSTG 1656

Query: 1292 PPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETGTTHT-------ATTATSNGGTGQ 1344
            PP  TH         TS A  A+   SNPP E+    T+ +       +TT  S      
Sbjct: 1657 PP--TH---------TSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAI 1705

Query: 1345 PEGGQQPPAGRPCETHQTTSTGTTMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAG 1404
                  PP+     T  TTS G T+S           +  R   +G   A  PS      
Sbjct: 1706 EMTSTAPPSTPTAPT--TTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 1763

Query: 1405 TALLAPFPTQRVCSNPPCETHETGTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDS- 1463
            T+   P PT     + P     TG     ++V      N      A  +     T GD+ 
Sbjct: 1764 TSAWTPTPTP---LSTPSIIRTTGLRPYPSSVLICCVLND--TYYAPGEEVYNGTYGDTC 1818

Query: 1464 --VNITSSSAI-------TTTVSSTLTRAVTTVTQSTPVPGPSVP-----PPEELQVSPG 1509
              VN + S  +        +T S T T + +T T S P   PS P     PPE     P 
Sbjct: 1819 YFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDP- 1877

Query: 1510 PRQQ 1513
            PRQ+
Sbjct: 1878 PRQE 1881



 Score = 38.1 bits (87), Expect = 0.088
 Identities = 37/144 (25%), Positives = 50/144 (34%), Gaps = 40/144 (27%)

Query: 402  IPATAATATSPTPNPVP-----------------SVPANPPKSPAPAAAAPAVQPLTQVG 444
            IP +  T  +PTP P                   +    PP+S  P  +     PLT+  
Sbjct: 1636 IPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE-S 1694

Query: 445  ITLL-------------PQAAPAPPTTT----TIQVLPTVPGSSISVPTAARTQG----- 482
             TLL             P + P  PTTT    T+   P+   S    PT   T G     
Sbjct: 1695 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 1754

Query: 483  VPAVLKVTGPQATTGTPLVTMRPA 506
             P+ ++ T   A T TP     P+
Sbjct: 1755 TPSTVQTTTTSAWTPTPTPLSTPS 1778


>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
          Length = 1388

 Score =  102 bits (254), Expect = 4e-21
 Identities = 256/1144 (22%), Positives = 413/1144 (36%), Gaps = 158/1144 (13%)

Query: 450  QAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGPQATTGTPLVTMRPASQA 509
            Q   +P   T    L  VP S    P         A+  +  P + +G     + PA  +
Sbjct: 64   QLMTSPVFDTMSAPLMGVPNSGALSPPLMPASDSGALSPLLMPASDSGALSPLLMPALDS 123

Query: 510  GKAPVTVTSLPAGVR----MVVP---TQSAQGTVIGSSPQMSGMAALAAAAA-------A 555
            G     +++   GV     M +P   T SA   V   S ++S +A  A ++        +
Sbjct: 124  GTLSPLLSTSEYGVMSPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPIMS 183

Query: 556  TQKIPPSSAPTVLSVPAGT-TIVKTMAVTPG---TTTLPATVKVASSPVMVSNPAT---- 607
            T      S P +L+  +G  + +    + PG   T  +PA    A SP+ +++  T    
Sbjct: 184  TSSSEAMSTPLMLAPDSGELSPILMQDMNPGVMSTQPVPAPSSEAMSPLQITDEDTEAMS 243

Query: 608  RMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSP 667
            ++L TA A    S    + T +  I ++  S   +     Q  +T   G   T  L+   
Sbjct: 244  KVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGTSPQPTSTQNSGGIPT-PLMSDL 302

Query: 668  ISVPGGSALISNLGKVMSVVQTKPVQTSAVTGQASTGP--------VTQIIQTKGPLPAG 719
             S    S L+S+ G   S V + P+ +    G+ ST P        ++  + T   LP+G
Sbjct: 303  DSGIMSSLLMSSPG---SEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTA--LPSG 357

Query: 720  TILKLVTSADGKPTTIITTTQ---------------ASGAGTKPTILGISSVSPSTTKPG 764
             +      A G       +TQ               ASG  + P +  + S + ST   G
Sbjct: 358  VMPTQTMPAPGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMG 417

Query: 765  T------TTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTSGTGAPAKIITAV 818
                   +T+ KT+P S  +T +  T  +S       ++   ++VM++     AK   A+
Sbjct: 418  APASGNMSTLQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQL-TMAKTSGAM 476

Query: 819  PKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVKPAVTTLVVKGTT 878
            P   TG  +    Q     A G+  T LR  P  G     PVT +A +      +    +
Sbjct: 477  P---TGSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPAS 533

Query: 879  GVTTLGTVTGTVSTSLAG------AGGHS--------TSASLATPITTLGTIATLSSQVI 924
            G  ++  +   VS +++       A G +        TS +++TP+ T  T  + S+ ++
Sbjct: 534  GSMSMLQMRAPVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLM 593

Query: 925  NPTAITV-SAAQTTLTAAGGLTTPTITMQPVSQPTQVTLITAPSGVEAQPVHDLPVSILA 983
              TA  V S  Q    A+G L+ P +T  P +  T  T     +  EA P      ++L 
Sbjct: 594  RDTASGVMSCPQMRSLASGALSKPLMT--PKASGTMFTEKMTTTASEAMP------TLLM 645

Query: 984  SPTTEQPTATVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGHPQP 1043
              T     +   + D+  G +    +    S     +  T T +   +  +        P
Sbjct: 646  RDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATVSGGMSMPLMRA---QDP 702

Query: 1044 TQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETG-------TTNTATTATS 1096
              +     R + +  +++  +  Q+   +   S  P ++   G       T++  +T T 
Sbjct: 703  GVMPASLMRAKVSGKMLSQPMSTQDPGGM---SMSPMKSMTAGGMQMNSPTSDVMSTPTV 759

Query: 1097 NMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGAL 1156
                    S P   T + G   +  T  SS G        RA A+G  A    S A GA+
Sbjct: 760  RAWTSETMSTPLMRTSDPGERPSLLTRASSSG-EMSLPLMRAPASGEIATPLRSPAYGAM 818

Query: 1157 EAAQ----GSKSQCQTRQTSAT-STTMTVMATGAPCSAGPLLGPSMAREPGGRSPAFVQL 1211
             A Q     S       Q  A  S  M++  T +  S G  +   + R P  R  +  Q+
Sbjct: 819  SAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGG--MSMPLMRAPDSRVTSTSQM 876

Query: 1212 APLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVT 1271
             P +S    + P       G  S  V   A    S     P     CE++     ST + 
Sbjct: 877  MPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPS---ACETV-----STELM 928

Query: 1272 VTALEALLCPSATVTQVC---SNPPCETHETGTTNTATTSNAGSAQRVCSNPPCETHETG 1328
              +    +  + T   V    S P      +GT      S   S +   S P  ET  +G
Sbjct: 929  RASASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEM--SMPLMETMASG 986

Query: 1329 TTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGT----TMSVSVGALLPDATSSH 1384
             T T  T+ +N               R     QTT T +    T  +   A    +TS  
Sbjct: 987  ATSTLQTSVANS--------------RSMSLSQTTYTVSGRMATAPIRASASGARSTSFM 1032

Query: 1385 RTVESGLEVAAAPSVTPQA-GTALLAPFPT---QRVCSNPPCETHETGTTHTATTVTSNM 1440
            R   SG      P  T    G  +  P  T    R  S P       GT  T  T    M
Sbjct: 1033 RASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMSTPLMRASGPGTMSTPQTAFGVM 1092

Query: 1441 SSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTVTQSTPVPGPSVPP 1500
            S+   P   A+D GE  ++    +NIT+S +  T+  +  T            P  + PP
Sbjct: 1093 ST---PEIKATDSGEASTSH---INITASGSKPTSHMTATT------------PETAKPP 1134

Query: 1501 PEEL 1504
            P+E+
Sbjct: 1135 PKEV 1138



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 198/907 (21%), Positives = 348/907 (38%), Gaps = 128/907 (14%)

Query: 416  PVPSVPANPPKS--PAPAAAAPAVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSIS 473
            P+ SVP     S  P PA  A A+ P     +T LP      PT    Q +P  PGS   
Sbjct: 323  PLLSVPDAGEMSTLPKPAPDAEAMSPAL---MTALPSGVM--PT----QTMPA-PGSGAM 372

Query: 474  VPTAARTQGVPAVLKVTGPQATTGTPLVTMRP--ASQAGKAPVTVTSLPAGVRMVVPTQS 531
             P +  TQ V + +    P   T + +++  P  A  +G     +   PA   M     +
Sbjct: 373  SPWS--TQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNM----ST 426

Query: 532  AQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPA 591
             Q TV  S    + +  + ++   + +   ++A  V+S  A  T+ KT    P T ++ A
Sbjct: 427  LQKTVPASGAMTTSLMTVPSSGVMSTEQMSATASRVMS--AQLTMAKTSGAMP-TGSMKA 483

Query: 592  TVKV---ASSPVMVSNPATRMLKTAAAQVGTSVSSATNTSTRPIITVHKSGTVTVAQQAQ 648
              K    A++   +S P  R   + A       ++A+ T + P +TV  SG++++ Q   
Sbjct: 484  VAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRA 543

Query: 649  VVT---------TVVGGVTKTI---TLVKSPISVP------GGSALISNLGKVMSVVQTK 690
             V+         T+  G+T       +    +S P       GS     +    S V + 
Sbjct: 544  PVSEAMSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSC 603

Query: 691  PVQTSAVTGQASTGPVTQIIQTKGPLPAGTIL--KLVTSADGKPTTIITTTQASGAGTKP 748
            P   S  +G  S   +T       P  +GT+   K+ T+A     T++     SGA + P
Sbjct: 604  PQMRSLASGALSKPLMT-------PKASGTMFTEKMTTTASEAMPTLLMRDTVSGALSMP 656

Query: 749  TILGISS--VSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGIKSPITIITTKVMTS 806
             +   +S  +S S  +   +  + T  M+A          T S G+  P+     +    
Sbjct: 657  QMTDTASGGLSASLMRDTASGAMSTSQMTA----------TVSGGMSMPL----MRAQDP 702

Query: 807  GTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMGGVRLVTPVTVSAVK 866
            G   PA ++ A  K++   G+     +  +   G   + ++++  GG+++ +P +     
Sbjct: 703  GV-MPASLMRA--KVS---GKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMST 756

Query: 867  PAVTTLVVKGTTGVTTLGTVTGTVSTSLAGAGGHSTSASLATPITTLGTIATLSSQVINP 926
            P V     +  +      +  G   + L  A   S+S  ++ P+        +++ + +P
Sbjct: 757  PTVRAWTSETMSTPLMRTSDPGERPSLLTRA---SSSGEMSLPLMRAPASGEIATPLRSP 813

Query: 927  TAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTLI-TAPSGVEAQPVHDLPVSILASP 985
                +SA Q T TA+G +++      P+S    + L  +  SG  + P+   P S + S 
Sbjct: 814  AYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTST 873

Query: 986  TTEQPTA-----TVTIADSGQGDVQPGTVTLVCSNPPCETHETGTTNTATTTVVANLGGH 1040
            +   PTA     T+ +     G V         S+P      +GT +T            
Sbjct: 874  SQMMPTASGDMCTLPVRAPASGGV---------SSPLVRAPASGTMSTPLR--------- 915

Query: 1041 PQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVRVCSNPPCETHETGTTNTATTATSNMAG 1100
             +P+  + V      A++    +  Q    V    S P      +GT        S MA 
Sbjct: 916  -RPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGT--MPMPLMSAMAS 972

Query: 1101 QHGCSNPPCETHETGTTNTATTAMSSVGANHQRDARRACAAGTPAVIRISVATGALEA-A 1159
                S P  ET  +G T+T  T+++        ++R    + T   +   +AT  + A A
Sbjct: 973  GE-MSMPLMETMASGATSTLQTSVA--------NSRSMSLSQTTYTVSGRMATAPIRASA 1023

Query: 1160 QGSKSQCQTRQTSATSTTMTV-MATGAPCSAGPLLGPSMAREPGGRSPAFVQLAPLSSKV 1218
             G++S    R + + S  M +  AT + C  G  +    A +  G S       PL   +
Sbjct: 1024 SGARSTSFMRASVSGSMPMPLPRATASGCGMGMSMPQMTATDSRGMS------TPL---M 1074

Query: 1219 RLSSPSIKDLPAGRHSHAVSTAAMTRSSVGAGEPRMAPVCESLQGGSPSTTVTVTALEAL 1278
            R S P     P       +ST  +   +  +GE   + +  +  G  P++ +T T  E  
Sbjct: 1075 RASGPGTMSTPQTAFG-VMSTPEI--KATDSGEASTSHINITASGSKPTSHMTATTPETA 1131

Query: 1279 LCPSATV 1285
              P   V
Sbjct: 1132 KPPPKEV 1138



 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 252/1255 (20%), Positives = 427/1255 (34%), Gaps = 282/1255 (22%)

Query: 441  TQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVP---AVLKVTGPQATTG 497
            + V + ++  +A  P  T+T Q++ +    ++S P      GVP   A+     P + +G
Sbjct: 44   SHVQLPIVSTSASDPGGTST-QLMTSPVFDTMSAPL----MGVPNSGALSPPLMPASDSG 98

Query: 498  TPLVTMRPASQAGK-APVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAAT 556
                 + PAS +G  +P+ + +L +G    + + S  G +                    
Sbjct: 99   ALSPLLMPASDSGALSPLLMPALDSGTLSPLLSTSEYGVM-------------------- 138

Query: 557  QKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQ 616
                   +P ++++P   T+  T+ V P +  +      A S  +V  P           
Sbjct: 139  -------SPGMMTIPDFGTMSATLMVAPDSAEISPLAMPAPSSGVVCTPI---------- 181

Query: 617  VGTSVSSATNTSTRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSAL 676
            + TS S A +T   P++    SG ++      ++  +  GV  T      P+  P   A 
Sbjct: 182  MSTSSSEAMST---PLMLAPDSGELSPI----LMQDMNPGVMST-----QPVPAPSSEA- 228

Query: 677  ISNLGKVMSVVQTKPVQTSAVTGQAST----GPVTQIIQTKGPLPAGTILKLVTSADGKP 732
                   MS +Q     T A++    T    G ++ ++ +     A + L +   A G  
Sbjct: 229  -------MSPLQITDEDTEAMSKVLMTALASGEISSLLMSGTDSEAISSLIMSAVASGGT 281

Query: 733  TTIITTTQASGAGTKPTILGISSVSPSTTKPGTTTIIKTIPMSAIITQAGATGVTSSPGI 792
            +   T+TQ SG    P +  + S            I+ ++ MS+  ++  +T + S P  
Sbjct: 282  SPQPTSTQNSGGIPTPLMSDLDS-----------GIMSSLLMSSPGSEVMSTPLLSVPDA 330

Query: 793  KSPITIITTKVMTSGTGAPAKIITAVPKIATGHGQQGVTQVVLKGAPGQPGTILRTVPMG 852
                T+   K           ++TA+P         GV       APG        +   
Sbjct: 331  GEMSTL--PKPAPDAEAMSPALMTALPS--------GVMPTQTMPAPGSGA-----MSPW 375

Query: 853  GVRLVTPVTVSAVKPAVTTLVVKGTTGVTTLGTVTGTVSTSLAGA---GGHST------- 902
              + V    +S      T   V     V  L +  G +ST L GA   G  ST       
Sbjct: 376  STQNVDSEMMSNPPVRATASGVMSAPPVRALDS--GAMSTPLMGAPASGNMSTLQKTVPA 433

Query: 903  SASLATPITTLGTIATLSSQVINPTAITVSAAQTTLTAAGGLTTPTITMQPVSQPTQVTL 962
            S ++ T + T+ +   +S++ ++ TA  V +AQ T+    G   PT +M+ V++  Q   
Sbjct: 434  SGAMTTSLMTVPSSGVMSTEQMSATASRVMSAQLTMAKTSG-AMPTGSMKAVAK--QYKR 490

Query: 963  ITAPSGVEAQPVHDLP---------VSILASPTTEQPTATVTIADSGQGDVQPGTVTLVC 1013
             TA SG  + P+   P         V+  AS T   P  TV  + S         V+   
Sbjct: 491  ATA-SGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEAM 549

Query: 1014 SNPPCETHETGTTNTATTTVVANLGGHPQPTQVQFVCDRQEAAASLVTSTVGQQNGSVVR 1073
            S P   T  +G T+ A                      + +A  S   ST          
Sbjct: 550  SMPQMRTMASGLTSAA----------------------QMKAMTSGAMST---------- 577

Query: 1074 VCSNPPCETHETGTTNTATTATSNMAGQHGCSNPPCETHETGTTNTATTAMSSVGANHQR 1133
                 P  T +T  + +        +G   C  P   +  +G  +       + G     
Sbjct: 578  -----PLMTAQTSGSTSTLLMRDTASGVMSC--PQMRSLASGALSKPLMTPKASGTMFTE 630

Query: 1134 DARRACAAGTPAVIRISVATGAL------EAAQGSKSQCQTRQTSATSTTMTVMATGAPC 1187
                  +   P ++     +GAL      + A G  S    R T++ + + + M      
Sbjct: 631  KMTTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLMRDTASGAMSTSQMTATV-- 688

Query: 1188 SAGPLLGPSMAREPGGRSPAFVQLAPLSSKVRLSSPSIKDLPAGRHSHAVSTAAMTRSSV 1247
             +G +  P M  +  G  PA +  A +S K+ LS P     P G     +S + M   + 
Sbjct: 689  -SGGMSMPLMRAQDPGVMPASLMRAKVSGKM-LSQPMSTQDPGG-----MSMSPMKSMTA 741

Query: 1248 GAGEPRMAPVCESLQGGSPSTTVTVTALEALLCPSATVTQVCSNPPCETHETGTTNTATT 1307
            G            +Q  SP++ V  T         A  ++  S P   T + G   +  T
Sbjct: 742  GG-----------MQMNSPTSDVMSTPTVR-----AWTSETMSTPLMRTSDPGERPSLLT 785

Query: 1308 SNAGSAQRVCSNPPCETHETGTTHTATTATSNGGTGQPEGGQQPPAGRPCETHQTTSTGT 1367
              + S +   S P      +G   T   + + G    P               Q T+T +
Sbjct: 786  RASSSGEM--SLPLMRAPASGEIATPLRSPAYGAMSAP---------------QMTATAS 828

Query: 1368 TMSVSVGALLPDATSSHRTVESGLEVAAAPSVTPQAGTALLAPFPTQRVCSNPPCETHET 1427
             M  S    +P   +    +   + +    S      +  L   P  RV S         
Sbjct: 829  GMMSS----MPQVKAP---ISGAMSMPLTRSTASGGMSMPLMRAPDSRVTS--------- 872

Query: 1428 GTTHTATTVTSNMSSNQDPPPAASDQGEVESTQGDSVNITSSSAITTTVSSTLTRAVTTV 1487
                     TS M       P AS         GD   +   +  +  VSS L RA  + 
Sbjct: 873  ---------TSQMM------PTAS---------GDMCTLPVRAPASGGVSSPLVRAPASG 908

Query: 1488 TQSTPVPGPSVPPPEELQVSPGPRQQLPPRQLLQSASTALMGESAE-VLSASQTPELPAA 1546
            T STP+  PS                       ++ ST LM  SA   +S +QT      
Sbjct: 909  TMSTPLRRPSA---------------------CETVSTELMRASASGHMSTAQT------ 941

Query: 1547 VDLSSTGEPSSGQESAGSAVVATVVVQPPPPTQSEVDQLSLPQELMAEAQAGTTTLMVTG 1606
                 T   S G         A+  +  P  +     ++S+P  +   A   T+TL  + 
Sbjct: 942  -----TAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPL-METMASGATSTLQTSV 995

Query: 1607 LTPEELAVTAAAEAAAQAAATEEAQALAIQAVLQAAQQAVMGTGEPMDTSEAAAT 1661
                 ++++      +   AT   +A A  A   +  +A +    PM    A A+
Sbjct: 996  ANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSMPMPLPRATAS 1050



 Score = 52.0 bits (123), Expect = 6e-06
 Identities = 74/361 (20%), Positives = 134/361 (37%), Gaps = 53/361 (14%)

Query: 403  PATAATATSPTPNPVPSVPANPPKSPAPAAAAPAVQPLTQV----GITLLPQAAPAPPTT 458
            PA  A +          + ++ P+  AP + A ++ PLT+     G+++    AP    T
Sbjct: 813  PAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSM-PLTRSTASGGMSMPLMRAPDSRVT 871

Query: 459  TTIQVLPTVPGSSISVPTAARTQGVPAVLKVTGP-QATTGTPL----------VTMRPAS 507
            +T Q++PT  G   ++P  A   G  +   V  P   T  TPL            +  AS
Sbjct: 872  STSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRAS 931

Query: 508  QAGKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAAAAAATQKIPPSSAPTV 567
             +G      T+      M  P   A  +     P MS MA+   +    + +   +  T+
Sbjct: 932  ASGHMSTAQTTAMVSGGMSKPLMRAPASGTMPMPLMSAMASGEMSMPLMETMASGATSTL 991

Query: 568  LSVPAGTTIVKTMAVTPGTTTLPATVKVASSPVMVSNPATRMLKTAAAQVGTSVSSATNT 627
                  T++  + +++   TT   + ++A++P+  S    R      A V  S+      
Sbjct: 992  -----QTSVANSRSMSLSQTTYTVSGRMATAPIRASASGARSTSFMRASVSGSM------ 1040

Query: 628  STRPIITVHKSGTVTVAQQAQVVTTVVGGVTKTITLVKSPISVPGGSALISNLGKVMSVV 687
               P+     SG        Q+  T   G++       +P+    G   +S       V+
Sbjct: 1041 -PMPLPRATASGCGMGMSMPQMTATDSRGMS-------TPLMRASGPGTMSTPQTAFGVM 1092

Query: 688  QTKPVQTSAVTGQASTGPVTQIIQTKGPLPAGTILKLVTSADGKPTTIITTTQASGAGTK 747
             T  ++ +  +G+AST  +                  +T++  KPT+ +T T    A   
Sbjct: 1093 STPEIKATD-SGEASTSHIN-----------------ITASGSKPTSHMTATTPETAKPP 1134

Query: 748  P 748
            P
Sbjct: 1135 P 1135


>gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens]
          Length = 372

 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 77/265 (29%), Positives = 118/265 (44%), Gaps = 31/265 (11%)

Query: 45  IVVFGGGNEG-IVDELHVYNTATNQWFIPAVRGDIPP-GCAAYGFVCDGTRLLVFGGMVE 102
           + + GG N      ++H  +   +QW +   +G +P    A++   C   R+ VFGG  +
Sbjct: 50  VFIVGGANPNRSFSDVHTMDLGKHQWDLDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQ 109

Query: 103 YGKYSNDLYELQASRWEWKRLKAKTPK-NGPPPCPRLGHSFSL-VGNKCYLFGGLANDSE 160
            G   N L  L      W      TP+   PPP PR  H+ S  +GN+ Y+FGG    ++
Sbjct: 110 SGN-RNCLQVLNPETRTWT-----TPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQ 163

Query: 161 DPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVI 220
             ++        L++ +    +  + W  P T G  P PR  H  V         +KL I
Sbjct: 164 PVQDT------KLHVFD----ANTLTWSQPETLGNPPSPRHGHVMVA------AGTKLFI 207

Query: 221 YGGMSGCRL-GDLWTLDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMD 279
           +GG++G R   DL  +DI  + W K + +G AP   + HSA  +G  +Y+FGG  P    
Sbjct: 208 HGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGAL 267

Query: 280 DVKVATHEKEWKCTNTLACLNLDTM 304
           D     H +E   T     L  DT+
Sbjct: 268 DTMYQYHTEEQHWT----LLKFDTL 288



 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 74/246 (30%), Positives = 114/246 (46%), Gaps = 45/246 (18%)

Query: 131 GPPPCPRLGHSFSL---VGN----KCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSG 183
           G  PC R+GHS S    VGN    K ++ GG          N  R  +D++ ++L    G
Sbjct: 25  GDSPCARVGHSCSYLPPVGNAKRGKVFIVGGA---------NPNRSFSDVHTMDL----G 71

Query: 184 VVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGG--MSGCRLGDLWTLDIDTLT 241
              WD+    G+LP  R  H + +         ++ ++GG   SG R   L  L+ +T T
Sbjct: 72  KHQWDLDTCKGLLP--RYEHASFI---PSCTPDRIWVFGGANQSGNR-NCLQVLNPETRT 125

Query: 242 WNKPSLSGVAPLPRSLH-SATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLN 300
           W  P ++   P PR+ H S+  IGN++YVFGG         + A   ++ K    L   +
Sbjct: 126 WTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGG-------GERGAQPVQDTK----LHVFD 174

Query: 301 LDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLE 360
            +T+ W     +TL  N P  R GH  VA  T+L+I  G  G R  + + + C D+  ++
Sbjct: 175 ANTLTWSQ--PETL-GNPPSPRHGHVMVAAGTKLFIHGGLAGDR--FYDDLHCIDISDMK 229

Query: 361 TEKPPP 366
            +K  P
Sbjct: 230 WQKLNP 235



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 38/120 (31%), Positives = 53/120 (44%), Gaps = 6/120 (5%)

Query: 27  GPVPRPRHGHRAVAIKELIVVFGG-GNEGIVDELHVYNTATNQWFIPAVRGDIPPGCAAY 85
           G  P PRHGH  VA    + + GG   +   D+LH  + +  +W      G  P GCAA+
Sbjct: 187 GNPPSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAGCAAH 246

Query: 86  GFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLV 145
             V  G  + +FGGM   G   + +Y+       W  LK  T      P  RL HS  ++
Sbjct: 247 SAVAMGKHVYIFGGMTPAGAL-DTMYQYHTEEQHWTLLKFDTLL----PPGRLDHSMCII 301



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 18/65 (27%), Positives = 33/65 (50%), Gaps = 2/65 (3%)

Query: 18  RWKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGN-EGIVDELHVYNTATNQWFIPAVRG 76
           +W+++   +G  P     H AVA+ + + +FGG    G +D ++ Y+T    W +     
Sbjct: 229 KWQKL-NPTGAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLLKFDT 287

Query: 77  DIPPG 81
            +PPG
Sbjct: 288 LLPPG 292


>gi|7657301 kelch domain containing 2 [Homo sapiens]
          Length = 406

 Score = 88.6 bits (218), Expect = 6e-17
 Identities = 77/273 (28%), Positives = 113/273 (41%), Gaps = 43/273 (15%)

Query: 30  PRPRHGHRAVAIKELIVVFGGGNEGIV----------DELHVYNTATNQWFIPAVRGDIP 79
           P  R GH AV+    + V+GG     V          +EL +YN  T +W      GD+P
Sbjct: 29  PAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVP 88

Query: 80  PGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWE----WKRLKAKTPKNGPPPC 135
           P  +    VC    L +FGG    G  +N  Y L +   +    W+R+  +    G PP 
Sbjct: 89  PSMSGSCAVCVDRVLYLFGGHHSRGN-TNKFYMLDSRSTDRVLQWERIDCQ----GIPPS 143

Query: 136 PRLGHSFSLVGNKCYLFGGLANDSEDP-------------KNNIPRYLND-LYILELRPG 181
            +      +  NK   FGG     ED               ++ PR  ND ++IL+    
Sbjct: 144 SKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTE-- 201

Query: 182 SGVVAWDIPITYGVLPPPRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTLT 241
                W  PIT G  P PR +H       +       V  G     R+ DL  L++DT  
Sbjct: 202 --TFTWSQPITTGKAPSPRAAHACATVGNRG-----FVFGGRYRDARMNDLHYLNLDTWE 254

Query: 242 WNKPSLSGVAPLPRSLHSATTI-GNKMYVFGGW 273
           WN+    G+ P+ RS HS T +  + +++FGG+
Sbjct: 255 WNELIPQGICPVGRSWHSLTPVSSDHLFLFGGF 287



 Score = 68.9 bits (167), Expect = 5e-11
 Identities = 74/287 (25%), Positives = 111/287 (38%), Gaps = 73/287 (25%)

Query: 88  VCDGTRLLVFGGMVEY---GKYSNDL-------YELQASRWEWKRLKAKTPKNGPPPCPR 137
           V DG  + V+GG       G Y   L       Y ++  RW+      K    G  P   
Sbjct: 38  VSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWK------KINTEGDVPPSM 91

Query: 138 LGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLP 197
            G     V    YLFGG        + N     N  Y+L+ R    V+ W+     G+ P
Sbjct: 92  SGSCAVCVDRVLYLFGG-----HHSRGNT----NKFYMLDSRSTDRVLQWERIDCQGIPP 142

Query: 198 PPRESHTAVVYTEKDNKKSKLVIYGGMSGCR----LG-------DLWT------------ 234
             ++     VY      K+KL+ +GG         LG         W             
Sbjct: 143 SSKDKLGVWVY------KNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVH 196

Query: 235 -LDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCT 293
            LD +T TW++P  +G AP PR+ H+  T+GN+ +VFGG       D ++          
Sbjct: 197 ILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGG----RYRDARM---------- 242

Query: 294 NTLACLNLDTMAWETILMDTLEDNIPRARAGHCAVAINT-RLYIWSG 339
           N L  LNLDT  W  ++   +    P  R+ H    +++  L+++ G
Sbjct: 243 NDLHYLNLDTWEWNELIPQGI---CPVGRSWHSLTPVSSDHLFLFGG 286



 Score = 41.6 bits (96), Expect = 0.008
 Identities = 55/245 (22%), Positives = 86/245 (35%), Gaps = 38/245 (15%)

Query: 134 PCPRLGHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITY 193
           P  R GH     G   +++GG  ++      +      +L+I  +  G     W    T 
Sbjct: 29  PAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGR----WKKINTE 84

Query: 194 GVLPPPRESHTAVVYTEKDNKKSKLVIYGGM-SGCRLGDLWTLDIDT----LTWNKPSLS 248
           G +PP      AV           L ++GG  S       + LD  +    L W +    
Sbjct: 85  GDVPPSMSGSCAVCVDRV------LYLFGGHHSRGNTNKFYMLDSRSTDRVLQWERIDCQ 138

Query: 249 GVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVK-----------VATHEKEWKCTNTLA 297
           G+ P  +         NK+  FGG+  L  D V             ++H + W   + + 
Sbjct: 139 GIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGW--NDHVH 196

Query: 298 CLNLDTMAWETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLW 357
            L+ +T  W            P  RA H    +  R +++ GR  YR A  N     DL 
Sbjct: 197 ILDTETFTWS---QPITTGKAPSPRAAHACATVGNRGFVFGGR--YRDARMN-----DLH 246

Query: 358 YLETE 362
           YL  +
Sbjct: 247 YLNLD 251



 Score = 39.3 bits (90), Expect = 0.040
 Identities = 40/166 (24%), Positives = 68/166 (40%), Gaps = 15/166 (9%)

Query: 25  WSGPV-----PRPRHGHRAVAIKELIVVFGGG-NEGIVDELHVYNTATNQWFIPAVRGDI 78
           WS P+     P PR  H    +     VFGG   +  +++LH  N  T +W     +G  
Sbjct: 205 WSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDARMNDLHYLNLDTWEWNELIPQGIC 264

Query: 79  PPGCAAYGFV-CDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPR 137
           P G + +         L +FGG     +  +D +    S+ EW +      +      PR
Sbjct: 265 PVGRSWHSLTPVSSDHLFLFGGFTTDKQPLSDAWTYCISKNEWIQFNHPYTEK-----PR 319

Query: 138 LGHSFSLVG-NKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGS 182
           L H+       +  +FGG AN+     ++   + N++ I  ++P S
Sbjct: 320 LWHTACASDEGEVIVFGGCANNL--LVHHRAAHSNEILIFSVQPKS 363



 Score = 37.7 bits (86), Expect = 0.12
 Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 8/94 (8%)

Query: 246 SLSGVAPLPRSLHSATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMA 305
           S+    P  RS H A + G  M+V+GG+    +  +      +E      L   N++T  
Sbjct: 23  SMELACPAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPRE-----ELWIYNMETGR 77

Query: 306 WETILMDTLEDNIPRARAGHCAVAINTRLYIWSG 339
           W+ I     E ++P + +G CAV ++  LY++ G
Sbjct: 78  WKKI---NTEGDVPPSMSGSCAVCVDRVLYLFGG 108


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.125    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 87,798,836
Number of Sequences: 37866
Number of extensions: 4689255
Number of successful extensions: 42698
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 1118
Number of HSP's that attempted gapping in prelim test: 21071
Number of HSP's gapped (non-prelim): 10440
length of query: 2035
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1917
effective length of database: 13,779,330
effective search space: 26414975610
effective search space used: 26414975610
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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