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Search of human proteins with 9790233
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9790233 solute carrier organic anion transporter family,
member 1B3 [Homo sapiens]
(702 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9790233 solute carrier organic anion transporter family, memb... 1409 0.0
gi|225543525 solute carrier organic anion transporter family, me... 1127 0.0
gi|116812593 liver-specific organic anion transporter 3TM12 [Hom... 1030 0.0
gi|8394291 solute carrier organic anion transporter family, memb... 630 e-180
gi|225543118 solute carrier organic anion transporter family, me... 608 e-174
gi|225543116 solute carrier organic anion transporter family, me... 546 e-155
gi|10835099 organic anion transporting polypeptide A [Homo sapiens] 521 e-148
gi|19913403 organic anion transporting polypeptide A [Homo sapiens] 521 e-148
gi|225543114 solute carrier organic anion transporter family, me... 494 e-139
gi|222831575 solute carrier organic anion transporter family, me... 395 e-110
gi|222831573 solute carrier organic anion transporter family, me... 395 e-110
gi|188528663 solute carrier organic anion transporter family, me... 358 7e-99
gi|223634012 solute carrier organic anion transporter family, me... 339 5e-93
gi|6005820 solute carrier organic anion transporter family, memb... 339 5e-93
gi|225637473 solute carrier organic anion transporter family, me... 338 1e-92
gi|38679890 solute carrier organic anion transporter family, mem... 337 3e-92
gi|39777594 solute carrier organic anion transporter family memb... 311 1e-84
gi|225637475 solute carrier organic anion transporter family, me... 300 2e-81
gi|225637477 solute carrier organic anion transporter family, me... 268 1e-71
gi|223634014 solute carrier organic anion transporter family, me... 265 1e-70
gi|93277099 solute carrier organic anion transporter family, mem... 213 6e-55
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 39 0.013
gi|11863156 RECK protein precursor [Homo sapiens] 37 0.048
gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo ... 34 0.53
gi|54873613 agrin [Homo sapiens] 33 1.2
gi|12383051 transmembrane protein with EGF-like and two follista... 33 1.2
gi|118600969 C-type lectin domain family 17, member A [Homo sapi... 33 1.2
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 32 1.5
gi|169790839 solute carrier family 1 (glial high affinity glutam... 32 2.0
gi|223717983 solute carrier family 37 (glycerol-3-phosphate tran... 32 2.6
>gi|9790233 solute carrier organic anion transporter family, member
1B3 [Homo sapiens]
Length = 702
Score = 1409 bits (3646), Expect = 0.0
Identities = 702/702 (100%), Positives = 702/702 (100%)
Query: 1 MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFD 60
MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFD
Sbjct: 1 MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFD 60
Query: 61 ISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGY 120
ISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGY
Sbjct: 61 ISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGY 120
Query: 121 YRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNML 180
YRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNML
Sbjct: 121 YRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNML 180
Query: 181 RGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYV 240
RGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYV
Sbjct: 181 RGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYV 240
Query: 241 DLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLK 300
DLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLK
Sbjct: 241 DLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLK 300
Query: 301 TNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVF 360
TNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVF
Sbjct: 301 TNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVF 360
Query: 361 KYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFL 420
KYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFL
Sbjct: 361 KYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFL 420
Query: 421 FQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGIT 480
FQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGIT
Sbjct: 421 FQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGIT 480
Query: 481 YLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAI 540
YLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAI
Sbjct: 481 YLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAI 540
Query: 541 QVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCM 600
QVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCM
Sbjct: 541 QVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCM 600
Query: 601 KWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASD 660
KWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASD
Sbjct: 601 KWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASD 660
Query: 661 NERKVMDEANLEFLNNGEHFVPSAGTDSKTCNLDMQDNAAAN 702
NERKVMDEANLEFLNNGEHFVPSAGTDSKTCNLDMQDNAAAN
Sbjct: 661 NERKVMDEANLEFLNNGEHFVPSAGTDSKTCNLDMQDNAAAN 702
>gi|225543525 solute carrier organic anion transporter family,
member 1B1 [Homo sapiens]
Length = 691
Score = 1127 bits (2916), Expect = 0.0
Identities = 551/690 (79%), Positives = 611/690 (88%), Gaps = 1/690 (0%)
Query: 1 MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFD 60
MDQ+QHLNKTAE+ SE KKTR CNG KMFLAALS S+IAK LG IIMK SI IERRF+
Sbjct: 1 MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFE 60
Query: 61 ISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGY 120
ISSSL G IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGC +MG G +LT+LPHFFMGY
Sbjct: 61 ISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGY 120
Query: 121 YRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNML 180
YRYSKET+IN SENSTS+LSTCLINQ LS N SPEIV K C+KESGS+MWIYVFMGNML
Sbjct: 121 YRYSKETNINSSENSTSTLSTCLINQILSLNRASPEIVGKGCLKESGSYMWIYVFMGNML 180
Query: 181 RGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYV 240
RGIGETPIVPLG+SYIDDFAKEGHSSLYLG LNAI MIGP+IGF LGSLF+KMYVDIGYV
Sbjct: 181 RGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYV 240
Query: 241 DLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLK 300
DLSTIRITP DSRWVGAWWL FLVSGLFSIISSIPFFFLP+ PNKPQKERK SLSLHVL+
Sbjct: 241 DLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASLSLHVLE 300
Query: 301 TNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVF 360
TND+++QTANLTNQGKN+TKNVTGFFQS KSILTNPLYV+F+LLTLLQVSS+IG+FTYVF
Sbjct: 301 TNDEKDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVF 360
Query: 361 KYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFL 420
KY+EQQYGQ +S AN LLG+ITIP A+GMFLGG+IIKKFKL+ VGIAKFS T+++S
Sbjct: 361 KYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLS 420
Query: 421 FQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGIT 480
F LLYF ++CE+KSVAGLT+TYDGNN V SH DVPLSYCNS+CNCDESQWEPVCGNNGIT
Sbjct: 421 FYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGNNGIT 480
Query: 481 YLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAI 540
Y+SPCLAGCKSSSG KK VFYNCSC+EVTGLQNRNYSAHLGECPRD+ CTRKF+ +VAI
Sbjct: 481 YISPCLAGCKSSSGNKKPIVFYNCSCLEVTGLQNRNYSAHLGECPRDDACTRKFYFFVAI 540
Query: 541 QVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCM 600
QV+N FSA GGT+ ++L VKIVQPELK+LA+GF SMVIR LGGILAPIYFGALID TC+
Sbjct: 541 QVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCI 600
Query: 601 KWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASD 660
KWSTN+CG +G+CR YNS F RVYLGLS LR +LVLYI+ I+AMKKK+Q KD AS+
Sbjct: 601 KWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASE 660
Query: 661 NERKVMDEANLEFLNNGEHFVPSAGTDSKT 690
N VMDEANLE LN +HFVPSAG DS+T
Sbjct: 661 N-GSVMDEANLESLNKNKHFVPSAGADSET 689
>gi|116812593 liver-specific organic anion transporter 3TM12 [Homo
sapiens]
Length = 640
Score = 1030 bits (2663), Expect = 0.0
Identities = 499/637 (78%), Positives = 556/637 (87%)
Query: 48 MKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTG 107
MKIS TQIERRF+ISSSL GLIDGSFEIGNL VIVFVSYFGSKLHRPKLIGIGC LMGTG
Sbjct: 1 MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTG 60
Query: 108 SILTSLPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESG 167
SIL +LPHFFMGYYRYSKET+I+PSENSTS+L CLINQ LS N T EI+E+ CVKESG
Sbjct: 61 SILMALPHFFMGYYRYSKETNIDPSENSTSNLPNCLINQMLSLNRTPSEIIERGCVKESG 120
Query: 168 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALG 227
SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLG++N +GM G V F LG
Sbjct: 121 SHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLG 180
Query: 228 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQ 287
SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSG+ SIISSIPFFFLP NPNKPQ
Sbjct: 181 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQ 240
Query: 288 KERKISLSLHVLKTNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLL 347
KERK+SL LHVLKTND RNQ ANLTN+ K +TKNVTGFFQSLKSILTNPLYVIF++ TLL
Sbjct: 241 KERKVSLFLHVLKTNDKRNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLL 300
Query: 348 QVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGI 407
+SS+I S TY+ K +EQQYG SAS NFLLG++ +P VA GMF GG+IIKKFKLSLVG+
Sbjct: 301 HMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGL 360
Query: 408 AKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDE 467
AK +F ++ + L Q+LYF LICESKSVAGLTLTYDGN+ V SHVDVPLSYCNSECNCDE
Sbjct: 361 AKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDE 420
Query: 468 SQWEPVCGNNGITYLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRD 527
SQWEPVCGNNGITYLSPCLAGCKSSSG K+ VFYNCSCVEV GLQN+NYSAHLGECPRD
Sbjct: 421 SQWEPVCGNNGITYLSPCLAGCKSSSGNKEPIVFYNCSCVEVIGLQNKNYSAHLGECPRD 480
Query: 528 NTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILA 587
+ CTRK ++Y IQV+++ A G T++ +L ++IVQPELKALA+GF SM++R+LGGIL
Sbjct: 481 DACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILV 540
Query: 588 PIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAM 647
PIYFGALID TCMKWSTNSCGA+GACRIYNS + GR + GL +AL FP LVL VFIF +
Sbjct: 541 PIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVV 600
Query: 648 KKKFQGKDTKASDNERKVMDEANLEFLNNGEHFVPSA 684
+KK GKDTK +NER+VMDEANLEFLN+ EHFVPSA
Sbjct: 601 RKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSA 637
>gi|8394291 solute carrier organic anion transporter family, member
1C1 isoform 2 [Homo sapiens]
Length = 712
Score = 630 bits (1624), Expect = e-180
Identities = 308/652 (47%), Positives = 439/652 (67%), Gaps = 12/652 (1%)
Query: 9 KTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGL 68
KT +S EK+ C K+FL ALSF Y AKAL +K +ITQIERRFDI SSL G+
Sbjct: 26 KTEYPSSEEKQPC--CGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGV 83
Query: 69 IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETH 128
IDGSFEIGNLLVI FVSYFG+KLHRPK+IG GC++MG G++L ++P FFM Y+Y +
Sbjct: 84 IDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER--- 140
Query: 129 INPSENSTSSLSTCLINQT----LSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIG 184
+PS NST S+S CL+ + +S S + +C ++ S MWIYVF+GN+LRGIG
Sbjct: 141 YSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIG 200
Query: 185 ETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLST 244
ETPI PLGI+Y+DDFA E +++ Y+G + + +IGP+ GF LGSL AK+YVDIG+V+L
Sbjct: 201 ETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDH 260
Query: 245 IRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDD 304
I ITPKD +WVGAWWLG+L++G+ S+++++PF++LPK+ + Q + S K D
Sbjct: 261 ITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID 320
Query: 305 RNQTANLTNQGKN--VTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKY 362
+ T T QG+N + + F SLK++ NP+Y ++L + +Q +S G TY KY
Sbjct: 321 -DHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKY 379
Query: 363 MEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQ 422
+EQQYGQS+S ANF++G+I IP VA G+F GG ++KKF++S+ G AK +S+ +L
Sbjct: 380 IEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLF 439
Query: 423 LLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYL 482
L F L CE+ VAGLT++Y G V+ H S CNS C C E++WEP+CG NGITY+
Sbjct: 440 LSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYV 499
Query: 483 SPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQV 542
S CLAGC++S+ K+ +FYNC+CV + ++ N S +G C +DN C + F ++ I V
Sbjct: 500 SACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISV 559
Query: 543 INSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKW 602
I S + GG +L ++ ++P+LK+ A+G ++ IR L GI AP+YFG LID +C+KW
Sbjct: 560 ITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKW 619
Query: 603 STNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGK 654
CG++G+CR+Y+S F +YLGL++ L +++L I +F +KK + K
Sbjct: 620 GFKRCGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSK 671
>gi|225543118 solute carrier organic anion transporter family,
member 1C1 isoform 1 [Homo sapiens]
Length = 730
Score = 608 bits (1567), Expect = e-174
Identities = 297/619 (47%), Positives = 419/619 (67%), Gaps = 12/619 (1%)
Query: 9 KTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGL 68
KT +S EK+ C K+FL ALSF Y AKAL +K +ITQIERRFDI SSL G+
Sbjct: 26 KTEYPSSEEKQPC--CGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGV 83
Query: 69 IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETH 128
IDGSFEIGNLLVI FVSYFG+KLHRPK+IG GC++MG G++L ++P FFM Y+Y +
Sbjct: 84 IDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER--- 140
Query: 129 INPSENSTSSLSTCLINQT----LSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIG 184
+PS NST S+S CL+ + +S S + +C ++ S MWIYVF+GN+LRGIG
Sbjct: 141 YSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNECEVDTSSSMWIYVFLGNLLRGIG 200
Query: 185 ETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLST 244
ETPI PLGI+Y+DDFA E +++ Y+G + + +IGP+ GF LGSL AK+YVDIG+V+L
Sbjct: 201 ETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDH 260
Query: 245 IRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDD 304
I ITPKD +WVGAWWLG+L++G+ S+++++PF++LPK+ + Q + S K D
Sbjct: 261 ITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID 320
Query: 305 RNQTANLTNQGKN--VTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKY 362
+ T T QG+N + + F SLK++ NP+Y ++L + +Q +S G TY KY
Sbjct: 321 -DHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKY 379
Query: 363 MEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQ 422
+EQQYGQS+S ANF++G+I IP VA G+F GG ++KKF++S+ G AK +S+ +L
Sbjct: 380 IEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLF 439
Query: 423 LLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYL 482
L F L CE+ VAGLT++Y G V+ H S CNS C C E++WEP+CG NGITY+
Sbjct: 440 LSLFALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYV 499
Query: 483 SPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQV 542
S CLAGC++S+ K+ +FYNC+CV + ++ N S +G C +DN C + F ++ I V
Sbjct: 500 SACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISV 559
Query: 543 INSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKW 602
I S + GG +L ++ ++P+LK+ A+G ++ IR L GI AP+YFG LID +C+KW
Sbjct: 560 ITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKW 619
Query: 603 STNSCGAQGACRIYNSVFF 621
CG++G+CR+Y+S F
Sbjct: 620 GFKRCGSRGSCRLYDSNVF 638
>gi|225543116 solute carrier organic anion transporter family,
member 1C1 isoform 3 [Homo sapiens]
Length = 663
Score = 546 bits (1408), Expect = e-155
Identities = 281/648 (43%), Positives = 403/648 (62%), Gaps = 53/648 (8%)
Query: 9 KTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGL 68
KT +S EK+ C K+FL ALSF Y AKAL +K +ITQIERRFDI SSL G+
Sbjct: 26 KTEYPSSEEKQPC--CGELKVFLCALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGV 83
Query: 69 IDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETH 128
IDGSFEIGNLLVI FVSYFG+KLHRPK+IG GC++MG G++L ++P FFM Y+Y +
Sbjct: 84 IDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVGTLLIAMPQFFMEQYKYER--- 140
Query: 129 INPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPI 188
+PS NST S+S CL+ ES S + + V
Sbjct: 141 YSPSSNSTLSISPCLL--------------------ESSSQLPVSVM------------- 167
Query: 189 VPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRIT 248
++ S + G + + +IGP+ GF LGSL AK+YVDIG+V+L I IT
Sbjct: 168 ------------EKSKSKISNGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITIT 215
Query: 249 PKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDDRNQT 308
PKD +WVGAWWLG+L++G+ S+++++PF++LPK+ + Q + S K D + T
Sbjct: 216 PKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKSLPRSQSREDSNSSSEKSKFIID-DHT 274
Query: 309 ANLTNQGKN--VTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQ 366
T QG+N + + F SLK++ NP+Y ++L + +Q +S G TY KY+EQQ
Sbjct: 275 DYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQ 334
Query: 367 YGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYF 426
YGQS+S ANF++G+I IP VA G+F GG ++KKF++S+ G AK +S+ +L L F
Sbjct: 335 YGQSSSRANFVIGLINIPAVALGIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLF 394
Query: 427 PLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCL 486
L CE+ VAGLT++Y G V+ H S CNS C C E++WEP+CG NGITY+S CL
Sbjct: 395 ALGCENSDVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACL 454
Query: 487 AGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSL 546
AGC++S+ K+ +FYNC+CV + ++ N S +G C +DN C + F ++ I VI S
Sbjct: 455 AGCQTSNRSGKNIIFYNCTCVGIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSY 514
Query: 547 FSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNS 606
+ GG +L ++ ++P+LK+ A+G ++ IR L GI AP+YFG LID +C+KW
Sbjct: 515 TLSLGGIPGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKR 574
Query: 607 CGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGK 654
CG++G+CR+Y+S F +YLGL++ L +++L I +F +KK + K
Sbjct: 575 CGSRGSCRLYDSNVFRHIYLGLTVILGTVSILLSIAVLFILKKNYVSK 622
>gi|10835099 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 521 bits (1342), Expect = e-148
Identities = 261/633 (41%), Positives = 393/633 (62%), Gaps = 16/633 (2%)
Query: 17 EKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIG 76
E + R + KMFL A++ ++++K L G M +TQIER+F+I +SL G I+GSFEIG
Sbjct: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
Query: 77 NLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENST 136
NLL+I+FVSYFG+KLHRP +IGIGC++MG G L SLPHF M Y Y E+ ++ S N +
Sbjct: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEY--ESTVSVSGNLS 126
Query: 137 SSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYI 196
S+ C+ N T T +C KE S MW+YV +GN++RG+GETPI+PLGISYI
Sbjct: 127 SNSFLCMENGTQILRPTQDP---SECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYI 183
Query: 197 DDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVG 256
+DFAK +S LY+G + +IGP+IG L S A +YVD G+V+ + ITP D+RWVG
Sbjct: 184 EDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVG 243
Query: 257 AWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDDRNQTANLTNQGK 316
AWW GFL+ +++++IPFFFLP K + + ++K ++ Q + +
Sbjct: 244 AWWFGFLICAGVNVLTAIPFFFLPNTLPK----EGLETNADIIKNENEDKQKEEVKKEKY 299
Query: 317 NVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANF 376
+TK+ F +KS+ NP+Y++F+L++++Q ++F+ +++ KY+EQQYG S+S A F
Sbjct: 300 GITKD---FLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIF 356
Query: 377 LLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVA 436
L+GI +P + G +GG I+KKFK+++ A S++ +L L F + CE+ SV
Sbjct: 357 LMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVV 416
Query: 437 GLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIK 496
G+ +Y+G + + CN +CNC W+PVCGNNG++YLS CLAGC++S G
Sbjct: 417 GINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTG 476
Query: 497 KHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFI 556
+ VF NCSC++ +G N SA LG C + C+ ++ + ++S +
Sbjct: 477 INMVFQNCSCIQTSG----NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGY 532
Query: 557 LLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIY 616
++ ++ ++ E K+L +G + R GI APIYFGAL+D TC+ W T CG GACRIY
Sbjct: 533 MVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIY 592
Query: 617 NSVFFGRVYLGLSIALRFPALVLYIVFIFAMKK 649
+S F +YLGL ALR + V ++ + ++K
Sbjct: 593 DSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|19913403 organic anion transporting polypeptide A [Homo sapiens]
Length = 670
Score = 521 bits (1342), Expect = e-148
Identities = 261/633 (41%), Positives = 393/633 (62%), Gaps = 16/633 (2%)
Query: 17 EKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIG 76
E + R + KMFL A++ ++++K L G M +TQIER+F+I +SL G I+GSFEIG
Sbjct: 9 ETHRIRCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIG 68
Query: 77 NLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENST 136
NLL+I+FVSYFG+KLHRP +IGIGC++MG G L SLPHF M Y Y E+ ++ S N +
Sbjct: 69 NLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEY--ESTVSVSGNLS 126
Query: 137 SSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYI 196
S+ C+ N T T +C KE S MW+YV +GN++RG+GETPI+PLGISYI
Sbjct: 127 SNSFLCMENGTQILRPTQDP---SECTKEVKSLMWVYVLVGNIVRGMGETPILPLGISYI 183
Query: 197 DDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVG 256
+DFAK +S LY+G + +IGP+IG L S A +YVD G+V+ + ITP D+RWVG
Sbjct: 184 EDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVG 243
Query: 257 AWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDDRNQTANLTNQGK 316
AWW GFL+ +++++IPFFFLP K + + ++K ++ Q + +
Sbjct: 244 AWWFGFLICAGVNVLTAIPFFFLPNTLPK----EGLETNADIIKNENEDKQKEEVKKEKY 299
Query: 317 NVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANF 376
+TK+ F +KS+ NP+Y++F+L++++Q ++F+ +++ KY+EQQYG S+S A F
Sbjct: 300 GITKD---FLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIF 356
Query: 377 LLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVA 436
L+GI +P + G +GG I+KKFK+++ A S++ +L L F + CE+ SV
Sbjct: 357 LMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVV 416
Query: 437 GLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIK 496
G+ +Y+G + + CN +CNC W+PVCGNNG++YLS CLAGC++S G
Sbjct: 417 GINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGNNGLSYLSACLAGCETSIGTG 476
Query: 497 KHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFI 556
+ VF NCSC++ +G N SA LG C + C+ ++ + ++S +
Sbjct: 477 INMVFQNCSCIQTSG----NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGY 532
Query: 557 LLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIY 616
++ ++ ++ E K+L +G + R GI APIYFGAL+D TC+ W T CG GACRIY
Sbjct: 533 MVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIY 592
Query: 617 NSVFFGRVYLGLSIALRFPALVLYIVFIFAMKK 649
+S F +YLGL ALR + V ++ + ++K
Sbjct: 593 DSTTFRYIYLGLPAALRGSSFVPALIILILLRK 625
>gi|225543114 solute carrier organic anion transporter family,
member 1C1 isoform 4 [Homo sapiens]
Length = 612
Score = 494 bits (1271), Expect = e-139
Identities = 235/524 (44%), Positives = 347/524 (66%), Gaps = 10/524 (1%)
Query: 104 MGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLSTCLINQT----LSFNGTSPEIVE 159
MG G++L ++P FFM Y+Y + +PS NST S+S CL+ + +S S +
Sbjct: 1 MGVGTLLIAMPQFFMEQYKYER---YSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKIS 57
Query: 160 KDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIG 219
+C ++ S MWIYVF+GN+LRGIGETPI PLGI+Y+DDFA E +++ Y+G + + +IG
Sbjct: 58 NECEVDTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIG 117
Query: 220 PVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFL 279
P+ GF LGSL AK+YVDIG+V+L I ITPKD +WVGAWWLG+L++G+ S+++++PF++L
Sbjct: 118 PIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYL 177
Query: 280 PKNPNKPQKERKISLSLHVLKTNDDRNQTANLTNQGKN--VTKNVTGFFQSLKSILTNPL 337
PK+ + Q + S K D + T T QG+N + + F SLK++ NP+
Sbjct: 178 PKSLPRSQSREDSNSSSEKSKFIID-DHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPV 236
Query: 338 YVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFII 397
Y ++L + +Q +S G TY KY+EQQYGQS+S ANF++G+I IP VA G+F GG ++
Sbjct: 237 YFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVM 296
Query: 398 KKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLS 457
KKF++S+ G AK +S+ +L L F L CE+ VAGLT++Y G V+ H S
Sbjct: 297 KKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSYQGTKPVSYHERALFS 356
Query: 458 YCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNY 517
CNS C C E++WEP+CG NGITY+S CLAGC++S+ K+ +FYNC+CV + ++ N
Sbjct: 357 DCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCVGIAASKSGNS 416
Query: 518 SAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSM 577
S +G C +DN C + F ++ I VI S + GG +L ++ ++P+LK+ A+G ++
Sbjct: 417 SGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQLKSFALGIYTL 476
Query: 578 VIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFF 621
IR L GI AP+YFG LID +C+KW CG++G+CR+Y+S F
Sbjct: 477 AIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVF 520
>gi|222831575 solute carrier organic anion transporter family,
member 3A1 isoform 1 [Homo sapiens]
Length = 710
Score = 395 bits (1016), Expect = e-110
Identities = 226/651 (34%), Positives = 355/651 (54%), Gaps = 29/651 (4%)
Query: 11 AESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLID 70
A+ +KKK + K+FL + +A+ G + +T +ERRF++ S+ G+I
Sbjct: 23 AQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIA 82
Query: 71 GSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHIN 130
SFEIGNL +I+FVSYFG++ HRP+LIG G ++M G++L++LP F Y+Y
Sbjct: 83 SSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEA----G 138
Query: 131 PSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMG-NMLRGIGETPIV 189
C N + G P+++ C + ++M + +G +L GIG TP+
Sbjct: 139 EIRWGAEGRDVCAANGSGGDEGPDPDLI---CRNRTATNMMYLLLIGAQVLLGIGATPVQ 195
Query: 190 PLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITP 249
PLG+SYIDD + SSLY+G L + + GP GF LGS K+YVD ++D S + ITP
Sbjct: 196 PLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITP 255
Query: 250 KDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTND-DRNQT 308
D RW+GAWW GFL+ G SS+ F P++ P E + +L + +R +
Sbjct: 256 DDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQS-LPPHSEPAMESEQAMLSEREYERPKP 314
Query: 309 ANLTNQGKNVTKNVTGFFQSL-------KSILTNPLYVIFLLLTLLQVSSFIGSFTYVFK 361
+N + + FQ L K +L+NP++ +L ++++ G ++ K
Sbjct: 315 SNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGK 374
Query: 362 YMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLF 421
Y+EQQ+ + S AN LLG+ IP G+FLGG ++KK LS +G + + L +++S
Sbjct: 375 YLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTAC 434
Query: 422 QLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITY 481
+ + L C++ VAG+T+ Y + + S +D P S CN+ C C + PVCG +GITY
Sbjct: 435 YVSFLFLGCDTGPVAGVTVPYGNSTAPGSALD-PYSPCNNNCECQTDSFTPVCGADGITY 493
Query: 482 LSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQ 541
LS C AGC S T C+C +T + N + G+CP C F ++ +
Sbjct: 494 LSACFAGCNS-------TNLTGCAC--LTTVPAENATVVPGKCPSPG-CQEAFLTFLCVM 543
Query: 542 VINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMK 601
I SL A T +++ ++ V PELK+ A+G +++R LG I P+ FGA ID TC+
Sbjct: 544 CICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLF 603
Query: 602 WSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQ 652
WST CG QGAC +Y++V + +Y+ ++IAL+ A +LY ++K ++
Sbjct: 604 WST-FCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYK 653
>gi|222831573 solute carrier organic anion transporter family,
member 3A1 isoform 2 [Homo sapiens]
Length = 692
Score = 395 bits (1016), Expect = e-110
Identities = 226/651 (34%), Positives = 355/651 (54%), Gaps = 29/651 (4%)
Query: 11 AESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLID 70
A+ +KKK + K+FL + +A+ G + +T +ERRF++ S+ G+I
Sbjct: 23 AQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIA 82
Query: 71 GSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHIN 130
SFEIGNL +I+FVSYFG++ HRP+LIG G ++M G++L++LP F Y+Y
Sbjct: 83 SSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEA----G 138
Query: 131 PSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMG-NMLRGIGETPIV 189
C N + G P+++ C + ++M + +G +L GIG TP+
Sbjct: 139 EIRWGAEGRDVCAANGSGGDEGPDPDLI---CRNRTATNMMYLLLIGAQVLLGIGATPVQ 195
Query: 190 PLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITP 249
PLG+SYIDD + SSLY+G L + + GP GF LGS K+YVD ++D S + ITP
Sbjct: 196 PLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITP 255
Query: 250 KDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTND-DRNQT 308
D RW+GAWW GFL+ G SS+ F P++ P E + +L + +R +
Sbjct: 256 DDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQS-LPPHSEPAMESEQAMLSEREYERPKP 314
Query: 309 ANLTNQGKNVTKNVTGFFQSL-------KSILTNPLYVIFLLLTLLQVSSFIGSFTYVFK 361
+N + + FQ L K +L+NP++ +L ++++ G ++ K
Sbjct: 315 SNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGK 374
Query: 362 YMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLF 421
Y+EQQ+ + S AN LLG+ IP G+FLGG ++KK LS +G + + L +++S
Sbjct: 375 YLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTAC 434
Query: 422 QLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITY 481
+ + L C++ VAG+T+ Y + + S +D P S CN+ C C + PVCG +GITY
Sbjct: 435 YVSFLFLGCDTGPVAGVTVPYGNSTAPGSALD-PYSPCNNNCECQTDSFTPVCGADGITY 493
Query: 482 LSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQ 541
LS C AGC S T C+C +T + N + G+CP C F ++ +
Sbjct: 494 LSACFAGCNS-------TNLTGCAC--LTTVPAENATVVPGKCPSPG-CQEAFLTFLCVM 543
Query: 542 VINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMK 601
I SL A T +++ ++ V PELK+ A+G +++R LG I P+ FGA ID TC+
Sbjct: 544 CICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLF 603
Query: 602 WSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQ 652
WST CG QGAC +Y++V + +Y+ ++IAL+ A +LY ++K ++
Sbjct: 604 WST-FCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYK 653
>gi|188528663 solute carrier organic anion transporter family,
member 2A1 [Homo sapiens]
Length = 643
Score = 358 bits (920), Expect = 7e-99
Identities = 222/665 (33%), Positives = 348/665 (52%), Gaps = 40/665 (6%)
Query: 7 LNKTAESASSEKKKTR--RC-----NGFKMFLAALSFSYIAKALGGIIMKISITQIERRF 59
L K S S+ +R RC K+F+ + + L K S+T IE+RF
Sbjct: 4 LPKLGASQGSDTSTSRAGRCARSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRF 63
Query: 60 DISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMG 119
+SSS +GLI EI N ++I+FVSYFGS++HRP+LIGIG L + G+ + +LPHF
Sbjct: 64 GLSSSSSGLISSLNEISNAILIIFVSYFGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSE 123
Query: 120 YYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNM 179
Y+Y T + NS C + ++ KE+ S MW + + +
Sbjct: 124 PYQY---TLASTGNNSRLQAELCQ-KHWQDLPPSKCHSTTQNPQKETSS-MWGLMVVAQL 178
Query: 180 LRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGY 239
L GIG PI P GISY+DDF++ +S LY+ L AI + GP G+ LGS+ +++VD G
Sbjct: 179 LAGIGTVPIQPFGISYVDDFSEPSNSPLYISILFAISVFGPAFGYLLGSVMLQIFVDYGR 238
Query: 240 VDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVL 299
V+ + + + P D RW+GAWWLG L+S +++S PFFF P+ K
Sbjct: 239 VNTAAVNLVPGDPRWIGAWWLGLLISSALLVLTSFPFFFFPRAMPIGAKRAP-------- 290
Query: 300 KTNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYV 359
T D+ + ++G ++ + F +L N L+V+ +L S G T++
Sbjct: 291 ATADEARKLEEAKSRG-SLVDFIKRFPCIFLRLLMNSLFVLVVLAQCTFSSVIAGLSTFL 349
Query: 360 FKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISF 419
K++E+QYG SA++ANFL+G + +P A GM GG ++K+F SL I + + IS
Sbjct: 350 NKFLEKQYGTSAAYANFLIGAVNLPAAALGMLFGGILMKRFVFSLQAIPRIATTIITISM 409
Query: 420 LFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGI 479
+ + F + C + +VA + Y + S + H P C +C+C +S + PVCG+NGI
Sbjct: 410 ILCVPLFFMGCSTPTVAEV---YPPSTSSSIHPQSPA--CRRDCSCPDSIFHPVCGDNGI 464
Query: 480 TYLSPCLAGCKS---SSGIKKHTVFYNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFI 536
YLSPC AGC + SS K ++ NCSC VTG + SA G CP C F+
Sbjct: 465 EYLSPCHAGCSNINMSSATSKQLIYLNCSC--VTG---GSASAKTGSCP--VPCAH--FL 515
Query: 537 YVAIQVIN--SLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGAL 594
AI +I+ SL + ++ +++V E K+ A+G Q +++R L + +P +G
Sbjct: 516 LPAIFLISFVSLIACISHNPLYMMVLRVVNQEEKSFAIGVQFLLMRLLAWLPSPALYGLT 575
Query: 595 IDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGK 654
ID +C++W++ G +GAC Y++ YLGL + + ++L + +KK +
Sbjct: 576 IDHSCIRWNSLCLGRRGACAYYDNDALRDRYLGLQMGYKALGMLLLCFISWRVKKNKEYN 635
Query: 655 DTKAS 659
KA+
Sbjct: 636 VQKAA 640
>gi|223634012 solute carrier organic anion transporter family,
member 2B1 isoform 2 [Homo sapiens]
Length = 687
Score = 339 bits (870), Expect = 5e-93
Identities = 213/662 (32%), Positives = 342/662 (51%), Gaps = 49/662 (7%)
Query: 25 NGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFV 84
+ K+F+ S +A+ + +K SI+ +E+RF +SS +GL+ E+GN +IVFV
Sbjct: 24 HNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFV 83
Query: 85 SYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLS--TC 142
SYFGS++HRP++IG G +L+ +L +LPHF YRY + + ++ +SL T
Sbjct: 84 SYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTT 143
Query: 143 LINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKE 202
+ NG E + G +F+ L G+G PI P GISYIDDFA
Sbjct: 144 SAPASAPSNGNCSSYTETQHLSVVG-----IMFVAQTLLGVGGVPIQPFGISYIDDFAHN 198
Query: 203 GHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGF 262
+S LYLG L A+ M+GP + F LGSL ++YVDI + I +T KD RWVGAWWLGF
Sbjct: 199 SNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGF 258
Query: 263 LVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDD----RNQTANLTNQGKNV 318
L++ +++IP+FF PK P+++R++ VL D + + + G++
Sbjct: 259 LIAAGAVALAAIPYFFFPK--EMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGEST 316
Query: 319 TK-----------NVTGFFQSLKSILTNPL-YVIFLLLTLLQV---SSFIGSFTYVFKYM 363
K V F + +L L + IFLL+ L QV S G T++ K++
Sbjct: 317 KKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFL 376
Query: 364 EQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQL 423
E+Q+ +AS+AN L+G ++ P+V G+ +GG ++K+ L VG L ++ F L
Sbjct: 377 ERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSL 436
Query: 424 LYFPLICESKSVAGLTLTYDGNNSVASHVDVPLS-YCNSECNCDESQWEPVCG-NNGITY 481
F + C S +AG+T + ++H + LS C C+C + PVC + + Y
Sbjct: 437 PLFFIGCSSHQIAGIT------HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEY 490
Query: 482 LSPCLAGCKS---SSGIKKHTVFY-NCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIY 537
++PC AGC S + VFY NCSCV G C D+TC+ +
Sbjct: 491 ITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------EGNPVLAGSC--DSTCSHLVVPF 542
Query: 538 VAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDK 597
+ + + S + T +L ++ V+ E K LA+G Q M +R L + +P+ G+ ID
Sbjct: 543 LLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDT 602
Query: 598 TCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTK 657
TC+ W+ SCG + CR YN+ ++GL + +++ + + + ++++ + TK
Sbjct: 603 TCVHWAL-SCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTK 661
Query: 658 AS 659
S
Sbjct: 662 ES 663
>gi|6005820 solute carrier organic anion transporter family, member
2B1 isoform 1 [Homo sapiens]
Length = 709
Score = 339 bits (870), Expect = 5e-93
Identities = 213/662 (32%), Positives = 342/662 (51%), Gaps = 49/662 (7%)
Query: 25 NGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFV 84
+ K+F+ S +A+ + +K SI+ +E+RF +SS +GL+ E+GN +IVFV
Sbjct: 46 HNIKLFVLCHSLLQLAQLMISGYLKSSISTVEKRFGLSSQTSGLLASFNEVGNTALIVFV 105
Query: 85 SYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLS--TC 142
SYFGS++HRP++IG G +L+ +L +LPHF YRY + + ++ +SL T
Sbjct: 106 SYFGSRVHRPRMIGYGAILVALAGLLMTLPHFISEPYRYDNTSPEDMPQDFKASLCLPTT 165
Query: 143 LINQTLSFNGTSPEIVEKDCVKESGSHMWIYVFMGNMLRGIGETPIVPLGISYIDDFAKE 202
+ NG E + G +F+ L G+G PI P GISYIDDFA
Sbjct: 166 SAPASAPSNGNCSSYTETQHLSVVG-----IMFVAQTLLGVGGVPIQPFGISYIDDFAHN 220
Query: 203 GHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGF 262
+S LYLG L A+ M+GP + F LGSL ++YVDI + I +T KD RWVGAWWLGF
Sbjct: 221 SNSPLYLGILFAVTMMGPGLAFGLGSLMLRLYVDINQMPEGGISLTIKDPRWVGAWWLGF 280
Query: 263 LVSGLFSIISSIPFFFLPKNPNKPQKERKISLSLHVLKTNDD----RNQTANLTNQGKNV 318
L++ +++IP+FF PK P+++R++ VL D + + + G++
Sbjct: 281 LIAAGAVALAAIPYFFFPK--EMPKEKRELQFRRKVLAVTDSPARKGKDSPSKQSPGEST 338
Query: 319 TK-----------NVTGFFQSLKSILTNPL-YVIFLLLTLLQV---SSFIGSFTYVFKYM 363
K V F + +L L + IFLL+ L QV S G T++ K++
Sbjct: 339 KKQDGLVQIAPNLTVIQFIKVFPRVLLQTLRHPIFLLVVLSQVCLSSMAAGMATFLPKFL 398
Query: 364 EQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQL 423
E+Q+ +AS+AN L+G ++ P+V G+ +GG ++K+ L VG L ++ F L
Sbjct: 399 ERQFSITASYANLLIGCLSFPSVIVGIVVGGVLVKRLHLGPVGCGALCLLGMLLCLFFSL 458
Query: 424 LYFPLICESKSVAGLTLTYDGNNSVASHVDVPLS-YCNSECNCDESQWEPVCG-NNGITY 481
F + C S +AG+T + ++H + LS C C+C + PVC + + Y
Sbjct: 459 PLFFIGCSSHQIAGIT------HQTSAHPGLELSPSCMEACSCPLDGFNPVCDPSTRVEY 512
Query: 482 LSPCLAGCKS---SSGIKKHTVFY-NCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIY 537
++PC AGC S + VFY NCSCV G C D+TC+ +
Sbjct: 513 ITPCHAGCSSWVVQDALDNSQVFYTNCSCVV------EGNPVLAGSC--DSTCSHLVVPF 564
Query: 538 VAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDK 597
+ + + S + T +L ++ V+ E K LA+G Q M +R L + +P+ G+ ID
Sbjct: 565 LLLVSLGSALACLTHTPSFMLILRGVKKEDKTLAVGIQFMFLRILAWMPSPVIHGSAIDT 624
Query: 598 TCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTK 657
TC+ W+ SCG + CR YN+ ++GL + +++ + + + ++++ + TK
Sbjct: 625 TCVHWAL-SCGRRAVCRYYNNDLLRNRFIGLQFFFKTGSVICFALVLAVLRQQDKEARTK 683
Query: 658 AS 659
S
Sbjct: 684 ES 685
>gi|225637473 solute carrier organic anion transporter family,
member 5A1 isoform 1 [Homo sapiens]
Length = 848
Score = 338 bits (866), Expect = 1e-92
Identities = 227/692 (32%), Positives = 358/692 (51%), Gaps = 71/692 (10%)
Query: 7 LNKT-AESASSEKKKTRRC-----NGFKMFLAALSFSYIAKAL--GGIIMKISITQIERR 58
L+KT + S++ + RRC + FL + F +AL G + + IT IERR
Sbjct: 101 LSKTFSVSSALAMLQERRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSV-ITTIERR 159
Query: 59 FDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFM 118
+ + SS +GL+ F+IGNL+V+VFVSYFG + RP + +G LL+ G+ L +LPHF
Sbjct: 160 YSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFIS 219
Query: 119 GYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKD-CVKES-GSHMWIYVFM 176
Y+ + L+ N L G S +E C K+S G++ W+YV +
Sbjct: 220 PPYQIQE-------------LNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVAL 266
Query: 177 ---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKM 233
+L G+G TPI LG +Y+DD K+ +SSLYL + +G +GP +G+ LG L
Sbjct: 267 FICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGF 326
Query: 234 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKI 292
YVD + + + D R++G WW GFL+ + + P F PK P + +K++K
Sbjct: 327 YVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKK 382
Query: 293 SLSLHVLKTNDDRNQTANLTNQG-KNVT-----KNVTGFFQSLKSILTNPLYVIFLLLTL 346
S+ + +D + +N + Q K V+ K+V ++ IL+N + +F+ L+
Sbjct: 383 KFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTF-LFVSLSY 441
Query: 347 LQVSSFIGSF-TYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLV 405
S+ + +F T++ K++E Q+G AS+A+ G+I +P+ G+ LGG+IIKK KL
Sbjct: 442 TAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGAR 501
Query: 406 GIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNC 465
AK + + S +S L F + CES ++ G+ + Y S+ CN C C
Sbjct: 502 ESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGC 561
Query: 466 DESQWEPVCGNNGITYLSPCLAGCKS----SSGIKKHTVFYNCSCVE------------- 508
++EPVCG++GITY +PCLAGC + S+GI+ +T C+CV+
Sbjct: 562 KIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYT---ECTCVQSRQVITPPTVGQR 618
Query: 509 -------VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVK 561
V N N A G+C R F +++ I + +A + I++T++
Sbjct: 619 SQLRVVIVKTYLNENGYAVSGKCKRTCNTLIPFLVFL---FIVTFITACAQPSAIIVTLR 675
Query: 562 IVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFF 621
V+ E + A+G Q +++RTL I PIYFGA+ID TCM W CG QG+C YN F
Sbjct: 676 SVEDEERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSF 734
Query: 622 GRVYLGLSIALRFPALVLYIVFIFAMKKKFQG 653
VY GL+ L+F + + +++K K G
Sbjct: 735 RFVYFGLAAGLKFVGFIFIFLAWYSIKYKEDG 766
>gi|38679890 solute carrier organic anion transporter family, member
4C1 [Homo sapiens]
Length = 724
Score = 337 bits (863), Expect = 3e-92
Identities = 200/639 (31%), Positives = 332/639 (51%), Gaps = 58/639 (9%)
Query: 22 RRCNGFKMFLAALSFSYIAKALGGII---MKISITQIERRFDISSSLAGLIDGSFEIGNL 78
+RCN FL L + +A G ++ + ISI+ +E+R+++ SSL GLI S++I
Sbjct: 99 QRCNTPGGFL--LHYCLLAVTQGIVVNGLVNISISTVEKRYEMKSSLTGLISSSYDISFC 156
Query: 79 LVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSK--ETHINPSENST 136
L+ +FVS+FG + H+P+ + ++G G+++ SLP FF G Y+ E + NST
Sbjct: 157 LLSLFVSFFGERGHKPRWLAFAAFMIGLGALVFSLPQFFSGEYKLGSLFEDTCVTTRNST 216
Query: 137 SSLSTCLINQTLSFNGTSPEIVEKDCVKESGSHMWIYVF-MGNMLRGIGETPIVPLGISY 195
S S+ S ++YVF +G +L G G TP+ LG ++
Sbjct: 217 SCTSST-----------------------SSLSNYLYVFILGQLLLGAGGTPLYTLGTAF 253
Query: 196 IDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWV 255
+DD SSLY+G+ A+ ++GP IG+ LG +Y+D+ + + + T D RW+
Sbjct: 254 LDDSVPTHKSSLYIGTGYAMSILGPAIGYVLGGQLLTIYIDVAMGESTDV--TEDDPRWL 311
Query: 256 GAWWLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKISLSLHVLKTNDDRNQTANLTNQ 314
GAWW+GFL+S +F+ IPF PK+ P + + + H +N D
Sbjct: 312 GAWWIGFLLSWIFAWSLIIPFSCFPKHLPGTAEIQAGKTSQAHQSNSNAD---------- 361
Query: 315 GKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHA 374
K++ F +LK+++ N +++ +L T + G T++ K++E Q+G ++S A
Sbjct: 362 -VKFGKSIKDFPAALKNLMKNAVFMCLVLSTSSEALITTGFATFLPKFIENQFGLTSSFA 420
Query: 375 NFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKS 434
L G + IP A G LGGF++ KF+++ KF+ TS ++ ++ CE++
Sbjct: 421 ATLGGAVLIPGAALGQILGGFLVSKFRMTCKNTMKFALFTSGVALTLSFVFMYAKCENEP 480
Query: 435 VAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSG 494
AG++ +Y+G + + + + CN+ CNC S + PVCG +G+ Y SPC AGC +
Sbjct: 481 FAGVSESYNGTGELGNLI----APCNANCNCSRSYYYPVCG-DGVQYFSPCFAGCSNPVA 535
Query: 495 IKKHTVFYNCSCVE-----VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSA 549
+K V+YNCSC+E + + + A G+C T K I++ I I +F+
Sbjct: 536 HRKPKVYYNCSCIERKTEITSTAETFGFEAKAGKC---ETHCAKLPIFLCIFFIVIIFTF 592
Query: 550 TGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGA 609
GT + ++ V ++LA+G Q MV+R LG I PI FG ID TC+ W N CG
Sbjct: 593 MAGTPITVSILRCVNHRQRSLALGIQFMVLRLLGTIPGPIIFGFTIDSTCILWDINDCGI 652
Query: 610 QGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMK 648
+GAC IY+++ + + +S+ + + IF K
Sbjct: 653 KGACWIYDNIKMAHMLVAISVTCKVITMFFNGFAIFLYK 691
>gi|39777594 solute carrier organic anion transporter family member
4A1 [Homo sapiens]
Length = 722
Score = 311 bits (797), Expect = 1e-84
Identities = 196/634 (30%), Positives = 317/634 (50%), Gaps = 44/634 (6%)
Query: 26 GFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVS 85
G FL A +F + G I + IT +ERR+D+ S +GLI S++I L + FVS
Sbjct: 104 GILFFLCAAAFLQ-GMTVNGFINTV-ITSLERRYDLHSYQSGLIASSYDIAACLCLTFVS 161
Query: 86 YFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLSTCLIN 145
YFG H+P+ +G G LLMGTGS++ +LPHF G Y + + + TC N
Sbjct: 162 YFGGSGHKPRWLGWGVLLMGTGSLVFALPHFTAGRYEVELD----------AGVRTCPAN 211
Query: 146 QTLSFNGTSPEIVEKDCVKESGSHMWIYVFM-GNMLRGIGETPIVPLGISYIDDFAKEGH 204
P V D SG + VFM G L G+G TP+ LG++Y+D+ K
Sbjct: 212 ---------PGAVCAD--STSGLSRYQLVFMLGQFLHGVGATPLYTLGVTYLDENVKSSC 260
Query: 205 SSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLV 264
S +Y+ ++GP G+ +G +Y ++G +T + WVGAWW+GFL
Sbjct: 261 SPVYIAIFYTAAILGPAAGYLIGGALLNIYTEMG----RRTELTTESPLWVGAWWVGFLG 316
Query: 265 SGLFSIISSIPFFFLPKN-PNKPQKERKISLSLHVLKTNDDRNQTANLTNQGKNVTKNVT 323
SG + +++P P+ P + + +H LK + R + +N + K +
Sbjct: 317 SGAAAFFTAVPILGYPRQLPGSQRYAVMRAAEMHQLK-DSSRGEASN-----PDFGKTIR 370
Query: 324 GFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITI 383
S+ +L NP +++ L + + G T+ K++E Q+ SAS A L G + +
Sbjct: 371 DLPLSIWLLLKNPTFILLCLAGATEATLITGMSTFSPKFLESQFSLSASEAATLFGYLVV 430
Query: 384 PTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYD 443
P G FLGGF + K +L + KF +++S L +L F L C S +AG+T +Y
Sbjct: 431 PAGGGGTFLGGFFVNKLRLRGSAVIKFCLFCTVVS-LLGILVFSLHCPSVPMAGVTASYG 489
Query: 444 GNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSS--SGIKKHTVF 501
G+ H+++ + CN+ C+C + PVCG++G+ Y S C AGC ++ + + V+
Sbjct: 490 GSLLPEGHLNL-TAPCNAACSCQPEHYSPVCGSDGLMYFSLCHAGCPAATETNVDGQKVY 548
Query: 502 YNCSCVEVTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVK 561
+CSC+ L + A G+C +TC RK + V I V+ F+ + T++
Sbjct: 549 RDCSCIP-QNLSSGFGHATAGKC--TSTCQRKPLLLVFIFVV-IFFTFLSSIPALTATLR 604
Query: 562 IVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFF 621
V+ ++ A+G Q +V+R LGGI PI FG +IDK C+ W + CG QG+C +Y +
Sbjct: 605 CVRDPQRSFALGIQWIVVRILGGIPGPIAFGWVIDKACLLWQ-DQCGQQGSCLVYQNSAM 663
Query: 622 GRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKD 655
R L + + + ++ + + F K + D
Sbjct: 664 SRYILIMGLLYKVLGVLFFAIACFLYKPLSESSD 697
>gi|225637475 solute carrier organic anion transporter family,
member 5A1 isoform 3 [Homo sapiens]
Length = 793
Score = 300 bits (769), Expect = 2e-81
Identities = 210/685 (30%), Positives = 327/685 (47%), Gaps = 112/685 (16%)
Query: 7 LNKT-AESASSEKKKTRRC-----NGFKMFLAALSFSYIAKAL--GGIIMKISITQIERR 58
L+KT + S++ + RRC + FL + F +AL G + + IT IERR
Sbjct: 101 LSKTFSVSSALAMLQERRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSV-ITTIERR 159
Query: 59 FDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFM 118
+ + SS +GL+ F+IGNL+V+VFVSYFG + RP + +G LL+ G+ L +LPHF
Sbjct: 160 YSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFIS 219
Query: 119 GYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKD-CVKESG-SHMWIYVFM 176
Y+ + L+ N L G S +E C K+SG ++ W+YV +
Sbjct: 220 PPYQIQE-------------LNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVAL 266
Query: 177 ---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKM 233
+L G+G TPI LG +Y+DD K+ +SSLYL + +G +GP +G+ LG L
Sbjct: 267 FICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGF 326
Query: 234 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKI 292
YVD + + + D R++G WW GFL+ + + P F PK P + +K++K
Sbjct: 327 YVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKK 382
Query: 293 SLSLHVLKTNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSF 352
S+ + +D + +N + Q ++ GF + ++
Sbjct: 383 KFSVDAVSDDDVLKEKSNNSEQADKKVSSM-GFGKDVR---------------------- 419
Query: 353 IGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSF 412
G+I +P+ G+ LGG+IIKK KL AK +
Sbjct: 420 --------------------------GVIIVPSAGVGIVLGGYIIKKLKLGARESAKLAM 453
Query: 413 LTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEP 472
+ S +S L F + CES ++ G+ + Y S+ CN C C ++EP
Sbjct: 454 ICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGCKIHEYEP 513
Query: 473 VCGNNGITYLSPCLAGCKS----SSGIKKHTVFYNCSCVE-------------------- 508
VCG++GITY +PCLAGC + S+GI+ +T C+CV+
Sbjct: 514 VCGSDGITYFNPCLAGCVNSGNLSTGIRNYT---ECTCVQSRQVITPPTVGQRSQLRVVI 570
Query: 509 VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELK 568
V N N A G+C R F +++ I + +A + I++T++ V+ E +
Sbjct: 571 VKTYLNENGYAVSGKCKRTCNTLIPFLVFL---FIVTFITACAQPSAIIVTLRSVEDEER 627
Query: 569 ALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGL 628
A+G Q +++RTL I PIYFGA+ID TCM W CG QG+C YN F VY GL
Sbjct: 628 PFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQ-QECGVQGSCWEYNVTSFRFVYFGL 686
Query: 629 SIALRFPALVLYIVFIFAMKKKFQG 653
+ L+F + + +++K K G
Sbjct: 687 AAGLKFVGFIFIFLAWYSIKYKEDG 711
>gi|225637477 solute carrier organic anion transporter family,
member 5A1 isoform 2 [Homo sapiens]
Length = 687
Score = 268 bits (686), Expect = 1e-71
Identities = 177/527 (33%), Positives = 282/527 (53%), Gaps = 47/527 (8%)
Query: 7 LNKT-AESASSEKKKTRRC-----NGFKMFLAALSFSYIAKAL--GGIIMKISITQIERR 58
L+KT + S++ + RRC + FL + F +AL G + + IT IERR
Sbjct: 101 LSKTFSVSSALAMLQERRCLYVVLTDSRCFLVCMCFLTFIQALMVSGYLSSV-ITTIERR 159
Query: 59 FDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFM 118
+ + SS +GL+ F+IGNL+V+VFVSYFG + RP + +G LL+ G+ L +LPHF
Sbjct: 160 YSLKSSESGLLVSCFDIGNLVVVVFVSYFGGRGRRPLWLAVGGLLIAFGAALFALPHFIS 219
Query: 119 GYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKD-CVKES-GSHMWIYVFM 176
Y+ + L+ N L G S +E C K+S G++ W+YV +
Sbjct: 220 PPYQIQE-------------LNASAPNDGLCQGGNSTATLEPPACPKDSGGNNHWVYVAL 266
Query: 177 ---GNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKM 233
+L G+G TPI LG +Y+DD K+ +SSLYL + +G +GP +G+ LG L
Sbjct: 267 FICAQILIGMGSTPIYTLGPTYLDDNVKKENSSLYLAIMYVMGALGPAVGYLLGGLLIGF 326
Query: 234 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKI 292
YVD + + + D R++G WW GFL+ + + P F PK P + +K++K
Sbjct: 327 YVD----PRNPVHLDQNDPRFIGNWWSGFLLCAIAMFLVIFPMFTFPKKLPPRHKKKKKK 382
Query: 293 SLSLHVLKTNDDRNQTANLTNQG-KNVT-----KNVTGFFQSLKSILTNPLYVIFLLLTL 346
S+ + +D + +N + Q K V+ K+V ++ IL+N + +F+ L+
Sbjct: 383 KFSVDAVSDDDVLKEKSNNSEQADKKVSSMGFGKDVRDLPRAAVRILSNMTF-LFVSLSY 441
Query: 347 LQVSSFIGSF-TYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLV 405
S+ + +F T++ K++E Q+G AS+A+ G+I +P+ G+ LGG+IIKK KL
Sbjct: 442 TAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGYIIKKLKLGAR 501
Query: 406 GIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNC 465
AK + + S +S L F + CES ++ G+ + Y S+ CN C C
Sbjct: 502 ESAKLAMICSGVSLLCFSTLFIVGCESINLGGINIPYTTGPSLTMPHRNLTGSCNVNCGC 561
Query: 466 DESQWEPVCGNNGITYLSPCLAGCKS----SSGIKKHTVFYNCSCVE 508
++EPVCG++GITY +PCLAGC + S+GI+ +T C+CV+
Sbjct: 562 KIHEYEPVCGSDGITYFNPCLAGCVNSGNLSTGIRNYT---ECTCVQ 605
>gi|223634014 solute carrier organic anion transporter family,
member 2B1 isoform 3 [Homo sapiens]
Length = 565
Score = 265 bits (676), Expect = 1e-70
Identities = 165/511 (32%), Positives = 264/511 (51%), Gaps = 42/511 (8%)
Query: 174 VFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKM 233
+F+ L G+G PI P GISYIDDFA +S LYLG L A+ M+GP + F LGSL ++
Sbjct: 48 MFVAQTLLGVGGVPIQPFGISYIDDFAHNSNSPLYLGILFAVTMMGPGLAFGLGSLMLRL 107
Query: 234 YVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKIS 293
YVDI + I +T KD RWVGAWWLGFL++ +++IP+FF PK P+++R++
Sbjct: 108 YVDINQMPEGGISLTIKDPRWVGAWWLGFLIAAGAVALAAIPYFFFPK--EMPKEKRELQ 165
Query: 294 LSLHVLKTNDD----RNQTANLTNQGKNVTK-----------NVTGFFQSLKSILTNPL- 337
VL D + + + G++ K V F + +L L
Sbjct: 166 FRRKVLAVTDSPARKGKDSPSKQSPGESTKKQDGLVQIAPNLTVIQFIKVFPRVLLQTLR 225
Query: 338 YVIFLLLTLLQV---SSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGG 394
+ IFLL+ L QV S G T++ K++E+Q+ +AS+AN L+G ++ P+V G+ +GG
Sbjct: 226 HPIFLLVVLSQVCLSSMAAGMATFLPKFLERQFSITASYANLLIGCLSFPSVIVGIVVGG 285
Query: 395 FIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDV 454
++K+ L VG L ++ F L F + C S +AG+T + ++H +
Sbjct: 286 VLVKRLHLGPVGCGALCLLGMLLCLFFSLPLFFIGCSSHQIAGIT------HQTSAHPGL 339
Query: 455 PLS-YCNSECNCDESQWEPVCG-NNGITYLSPCLAGCKS---SSGIKKHTVFY-NCSCVE 508
LS C C+C + PVC + + Y++PC AGC S + VFY NCSCV
Sbjct: 340 ELSPSCMEACSCPLDGFNPVCDPSTRVEYITPCHAGCSSWVVQDALDNSQVFYTNCSCVV 399
Query: 509 VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELK 568
G C D+TC+ ++ + + S + T +L ++ V+ E K
Sbjct: 400 ------EGNPVLAGSC--DSTCSHLVVPFLLLVSLGSALACLTHTPSFMLILRGVKKEDK 451
Query: 569 ALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGL 628
LA+G Q M +R L + +P+ G+ ID TC+ W+ SCG + CR YN+ ++GL
Sbjct: 452 TLAVGIQFMFLRILAWMPSPVIHGSAIDTTCVHWAL-SCGRRAVCRYYNNDLLRNRFIGL 510
Query: 629 SIALRFPALVLYIVFIFAMKKKFQGKDTKAS 659
+ +++ + + + ++++ + TK S
Sbjct: 511 QFFFKTGSVICFALVLAVLRQQDKEARTKES 541
>gi|93277099 solute carrier organic anion transporter family, member
6A1 [Homo sapiens]
Length = 719
Score = 213 bits (541), Expect = 6e-55
Identities = 154/637 (24%), Positives = 275/637 (43%), Gaps = 54/637 (8%)
Query: 24 CNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVF 83
CN + F+ I + + ++ +SI ++ + + + ++ S++I + LV +F
Sbjct: 102 CNNIRCFMIFYCILLICQGVVFGLIDVSIGDFQKEYQLKTIEKLALEKSYDISSGLVAIF 161
Query: 84 VSYFGSKLHRPKLIGI--GCLLMGTGSILTSLPHFFMGYYRYSKETHINPSENSTSSLST 141
++++G R K+I L+G GS+L + P IN EN S +
Sbjct: 162 IAFYGD---RKKVIWFVASSFLIGLGSLLCAFPS-------------IN-EENKQSKVGI 204
Query: 142 CLINQTLSFNGTSPEIVEKDCVKESGSHMWIYV---FMGNMLRGIGETPIVPLGISYIDD 198
I + + V C S Y+ +G ++GI P+ LGI++ID+
Sbjct: 205 EDICEEIK--------VVSGCQSSGISFQSKYLSFFILGQTVQGIAGMPLYILGITFIDE 256
Query: 199 FAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAW 258
+ +YLG MIG +G+ LG+ K V + + W+ W
Sbjct: 257 NVATHSAGIYLGIAECTSMIGYALGYVLGAPLVK--VPENTTSATNTTVNNGSPEWLWTW 314
Query: 259 WLGFLVSGLFSIISSIPFFFLPKN-PNKPQKERKISLSLHVLKTNDDRNQTANLTNQGKN 317
W+ FL + + + + IP P N P + + + LH D R + L
Sbjct: 315 WINFLFAAVVAWCTLIPLSCFPNNMPGSTRIKARKRKQLHFF---DSRLKDLKLGT---- 367
Query: 318 VTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFL 377
N+ +L ++ NP+ + L + IG+ ++ Y+E Q+ + + A L
Sbjct: 368 ---NIKDLCAALWILMKNPVLICLALSKATEYLVIIGASEFLPIYLENQFILTPTVATTL 424
Query: 378 LGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAG 437
G++ IP A G LGG I+ ++S + +F +TS+IS + + + C AG
Sbjct: 425 AGLVLIPGGALGQLLGGVIVSTLEMSCKALMRFIMVTSVISLILLVFIIFVRCNPVQFAG 484
Query: 438 LTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKK 497
+ YDG + ++ P CN +C C S + +CG + I Y SPC AGC S +
Sbjct: 485 INEDYDGTGKL-GNLTAP---CNEKCRCSSSIYSSICGRDDIEYFSPCFAGCTYSKAQNQ 540
Query: 498 HTVFYNCSCVE----VTGLQNRNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGT 553
++YNCSC++ + A G+C D C K +++A +FS G
Sbjct: 541 KKMYYNCSCIKEGLITADAEGDFIDARPGKC--DAKC-YKLPLFIAFIFSTLIFSGFSGV 597
Query: 554 TFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGAC 613
+L ++V +L++LA+G +++R G I P F + +C+ N CG G C
Sbjct: 598 PIVLAMTRVVPDKLRSLALGVSYVILRIFGTIPGPSIFKMSGETSCILRDVNKCGHTGRC 657
Query: 614 RIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKK 650
IYN + +G+ + ++ + F K++
Sbjct: 658 WIYNKTKMAFLLVGICFLCKLCTIIFTTIAFFIYKRR 694
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 39.3 bits (90), Expect = 0.013
Identities = 70/290 (24%), Positives = 118/290 (40%), Gaps = 42/290 (14%)
Query: 172 IYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNA-----IGMIGPV-IGFA 225
I +G +L G + LG S+I A S LY G ++ IG I P + A
Sbjct: 133 ILSLVGALLMGFSK-----LGPSHILIIAGRSISGLYCGLISGLVPMYIGEIAPTALRGA 187
Query: 226 LGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPN- 284
LG+ F ++ + G + I + + W + +SG+ +I+ S+ FF P++P
Sbjct: 188 LGT-FHQLAIVTGILISQIIGLEFILGNY-DLWHILLGLSGVRAILQSLLLFFCPESPRY 245
Query: 285 ---KPQKERKISLSLHVLKTNDDRNQTANLTNQGKNVTKNVTGFFQSLKSILTN-----P 336
K +E K SL L+ DD T ++ K + + S+ + TN P
Sbjct: 246 LYIKLDEEVKAKQSLKRLRGYDD--VTKDINEMRKEREEASSEQKVSIIQLFTNSSYRQP 303
Query: 337 LYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFL---- 392
+ V +L Q S G F Y + +A +G + + A +FL
Sbjct: 304 ILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPVYATIGVGAVNMVFTAVSVFLVEKA 363
Query: 393 -----------GGFIIKKF-KLSLVGIAKFSFLT--SMISFLFQLLYFPL 428
G F+ F + LV + KFS+++ SMI+ + +F +
Sbjct: 364 GRRSLFLIGMSGMFVCAIFMSVGLVLLNKFSWMSYVSMIAIFLFVSFFEI 413
>gi|11863156 RECK protein precursor [Homo sapiens]
Length = 971
Score = 37.4 bits (85), Expect = 0.048
Identities = 16/27 (59%), Positives = 19/27 (70%), Gaps = 1/27 (3%)
Query: 463 CNCDESQWEPVCGNNGITYLSPCLAGC 489
CNC + Q+ PVCG NG TY S C+A C
Sbjct: 633 CNCAD-QFVPVCGQNGRTYPSACIARC 658
Score = 32.0 bits (71), Expect = 2.0
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 11/53 (20%)
Query: 471 EPVCGNNGITYLSPCLA-----------GCKSSSGIKKHTVFYNCSCVEVTGL 512
EPVCG+NG TY S C A C++ + +H+ C+ V+ L
Sbjct: 758 EPVCGHNGETYSSVCAAYSDRVAVDYYGDCQAVGVLSEHSSVAECASVKCPSL 810
>gi|47679099 Kazal type serine protease inhibitor 5-like 2 [Homo
sapiens]
Length = 97
Score = 33.9 bits (76), Expect = 0.53
Identities = 16/53 (30%), Positives = 27/53 (50%)
Query: 454 VPLSYCNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHTVFYNCSC 506
V LS+ N N ++P+CG N ITY +PC+ +S + +++ C
Sbjct: 45 VNLSWYNGTVNPCPGLYQPICGTNFITYDNPCILCVESLKSHGRIRFYHDGKC 97
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 32.7 bits (73), Expect = 1.2
Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 459 CNSECNCDESQWEPVCGNNGITYLSPC---LAGCKSSSGI 495
C + +C PVCG++G+TY + C A C+S G+
Sbjct: 703 CVCDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGL 742
Score = 29.6 bits (65), Expect = 10.0
Identities = 12/26 (46%), Positives = 18/26 (69%), Gaps = 3/26 (11%)
Query: 463 CNCDE---SQWEPVCGNNGITYLSPC 485
C C + S ++PVCG++G+TY S C
Sbjct: 488 CECLQACSSLYDPVCGSDGVTYGSAC 513
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 32.7 bits (73), Expect = 1.2
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 6/46 (13%)
Query: 453 DVPLSYCNSECNCDESQWEPVCGNNGITYLSPCL---AGCKSSSGI 495
D C +CN D + PVCG+NG +Y + C A CK S I
Sbjct: 85 DTVTCVCQFKCNND---YVPVCGSNGESYQNECYLRQAACKQQSEI 127
>gi|118600969 C-type lectin domain family 17, member A [Homo
sapiens]
Length = 289
Score = 32.7 bits (73), Expect = 1.2
Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 2/52 (3%)
Query: 530 CTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRT 581
C +++ +Y+ + V+ SLF G T L+ + + EL+ L+ FQ M RT
Sbjct: 148 CQKRWMVYLCLLVVTSLFLGCLGLTVTLIKYQELMEELRMLS--FQQMTWRT 197
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 32.3 bits (72), Expect = 1.5
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 6/42 (14%)
Query: 461 SECNCDE---SQWEPVCGNNGITYLSPCL---AGCKSSSGIK 496
+ C CD +Q PVCG++G+ Y S C A C+ ++ ++
Sbjct: 1755 ARCGCDHDCGAQGNPVCGSDGVVYASACRLREAACRQAAPLE 1796
>gi|169790839 solute carrier family 1 (glial high affinity glutamate
transporter), member 3 [Homo sapiens]
Length = 542
Score = 32.0 bits (71), Expect = 2.0
Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 380 IITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICES 432
++T+ V G LG F ++ +++S + FSF ++ + Q+L PLI S
Sbjct: 52 LLTVTAVIVGTILG-FTLRPYRMSYREVKYFSFPGELLMRMLQMLVLPLIISS 103
>gi|223717983 solute carrier family 37 (glycerol-3-phosphate
transporter), member 2 isoform 2 [Homo sapiens]
Length = 501
Score = 31.6 bits (70), Expect = 2.6
Identities = 26/115 (22%), Positives = 52/115 (45%), Gaps = 25/115 (21%)
Query: 170 MWIYVFMGNMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSL 229
+W +V + + G+ +T P ++ + ++ +G +G N+ +G + LGSL
Sbjct: 143 LWYFVVI-QVCNGLVQTTGWPSVVTCVGNWFGKGKRGFIMGIWNSHTSVGNI----LGSL 197
Query: 230 FAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLF-SIISSIPFFFLPKNP 283
A ++V+ G W L F+V G+ +++ I F FL ++P
Sbjct: 198 IAGIWVN-------------------GQWGLSFIVPGIITAVMGVITFLFLIEHP 233
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,175,572
Number of Sequences: 37866
Number of extensions: 1039726
Number of successful extensions: 2268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2137
Number of HSP's gapped (non-prelim): 61
length of query: 702
length of database: 18,247,518
effective HSP length: 109
effective length of query: 593
effective length of database: 14,120,124
effective search space: 8373233532
effective search space used: 8373233532
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.