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Search of human proteins with 95147559
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|95147559 ankyrin repeat domain 43 [Homo sapiens]
(549 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|95147559 ankyrin repeat domain 43 [Homo sapiens] 1098 0.0
gi|54607077 ankyrin repeat domain 57 [Homo sapiens] 182 9e-46
gi|71274172 ankyrin repeat domain 56 [Homo sapiens] 136 6e-32
gi|157743267 ankyrin repeat domain 58 [Homo sapiens] 125 1e-28
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 79 1e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 3e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 6e-11
gi|163965366 nascent polypeptide-associated complex alpha subuni... 66 7e-11
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 65 2e-10
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 65 2e-10
gi|118402590 myosin XV [Homo sapiens] 64 5e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 64 5e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 64 5e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 63 6e-10
gi|19924099 synapsin I isoform Ia [Homo sapiens] 63 8e-10
gi|19924097 synapsin I isoform Ib [Homo sapiens] 63 8e-10
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 62 1e-09
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 62 1e-09
gi|160707881 formin 2 [Homo sapiens] 62 2e-09
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 60 4e-09
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 60 4e-09
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens] 60 4e-09
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens] 60 4e-09
gi|11386183 WAS protein family, member 2 [Homo sapiens] 60 7e-09
gi|7706501 WW domain binding protein 11 [Homo sapiens] 60 7e-09
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 59 9e-09
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 59 9e-09
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 59 1e-08
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 58 2e-08
gi|222418647 mucin 7, secreted precursor [Homo sapiens] 58 3e-08
>gi|95147559 ankyrin repeat domain 43 [Homo sapiens]
Length = 549
Score = 1098 bits (2839), Expect = 0.0
Identities = 549/549 (100%), Positives = 549/549 (100%)
Query: 1 MALAAAAAAAAAGVSQAAVLGFLQEHGGKVRNSELLSRFKPLLDAGDPRGRAARRDRFKQ 60
MALAAAAAAAAAGVSQAAVLGFLQEHGGKVRNSELLSRFKPLLDAGDPRGRAARRDRFKQ
Sbjct: 1 MALAAAAAAAAAGVSQAAVLGFLQEHGGKVRNSELLSRFKPLLDAGDPRGRAARRDRFKQ 60
Query: 61 FVNNVAVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAP 120
FVNNVAVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAP
Sbjct: 61 FVNNVAVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAP 120
Query: 121 PLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSAD 180
PLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSAD
Sbjct: 121 PLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSAD 180
Query: 181 AAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLR 240
AAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLR
Sbjct: 181 AAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLR 240
Query: 241 RQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAP 300
RQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAP
Sbjct: 241 RQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAP 300
Query: 301 PPSAVPLEPSEHEWLVRTAGGRWTHQLHGLLLRDRGLAAKRDFMSGFTALHWAAKSGDGE 360
PPSAVPLEPSEHEWLVRTAGGRWTHQLHGLLLRDRGLAAKRDFMSGFTALHWAAKSGDGE
Sbjct: 301 PPSAVPLEPSEHEWLVRTAGGRWTHQLHGLLLRDRGLAAKRDFMSGFTALHWAAKSGDGE 360
Query: 361 MALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVRLGAQVHVRDHSGR 420
MALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVRLGAQVHVRDHSGR
Sbjct: 361 MALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVRLGAQVHVRDHSGR 420
Query: 421 RAYQYLRPGSSYALRRLLGDPGLRGTTEPDATGGGSGSLAARRPVQVAATILSSTTSAFL 480
RAYQYLRPGSSYALRRLLGDPGLRGTTEPDATGGGSGSLAARRPVQVAATILSSTTSAFL
Sbjct: 421 RAYQYLRPGSSYALRRLLGDPGLRGTTEPDATGGGSGSLAARRPVQVAATILSSTTSAFL 480
Query: 481 GVLADDLMLQDLARGLKKSSSFSKFLSASPMAPRKKTKIRGGLPAFSEISRRPTPGPLAG 540
GVLADDLMLQDLARGLKKSSSFSKFLSASPMAPRKKTKIRGGLPAFSEISRRPTPGPLAG
Sbjct: 481 GVLADDLMLQDLARGLKKSSSFSKFLSASPMAPRKKTKIRGGLPAFSEISRRPTPGPLAG 540
Query: 541 LVPSFPPTT 549
LVPSFPPTT
Sbjct: 541 LVPSFPPTT 549
>gi|54607077 ankyrin repeat domain 57 [Homo sapiens]
Length = 525
Score = 182 bits (461), Expect = 9e-46
Identities = 151/475 (31%), Positives = 204/475 (42%), Gaps = 69/475 (14%)
Query: 12 AGVSQAAVLGFLQEHGGKVRNSELLSRFKPLLDAGDPRGRAARRDRFKQFVNNVAVVK-- 69
A + AVL FL E GG+ ++EL+ F+ L G+P RA R FK+ VN VA V+
Sbjct: 11 AALGPEAVLRFLAERGGRALHAELVQHFRGAL-GGEPEQRARARAHFKELVNAVATVRVD 69
Query: 70 ELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPV 129
DG K+V L+K+ PS+P+ G PP ++V
Sbjct: 70 PADGAKYVHLKKR---------------FCEGPSEPS-----------GDPPRIQVTAEP 103
Query: 130 EPPGDLGLPTEPQDTP--GGPASEPAQPPGERSADPPLPA----LELAQATERPSADAAP 183
E P P P P S P Q +PP PA L + D P
Sbjct: 104 EAPDGPAGPEARDRLPDAAAPESLPGQGRELGEGEPPAPAHWPPLSAGARRKNSRRDVQP 163
Query: 184 PPRAPSEAASPCSDPP-----DAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPG 238
PR P+ S + P +A+ G Q+ PA LR G
Sbjct: 164 LPRTPAPGPSEDLELPPHGCEEADRGSSLVGATAQR------------PARQNLRDLVMG 211
Query: 239 LRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPA 298
QL P S SG G G G G S + S AEE +
Sbjct: 212 SSPQLKRSVCPGGSS------PGSSSGGGRGRGGGDSD--------SASVASSSAEEESS 257
Query: 299 APPPSAVPLEPSEHEWLVRTAGGRWTHQLHGLLLRDRGLAAKRDFMSGFTALHWAAKSGD 358
+V L+P EH W++ + G+W L GLL + GL KRDF++GFT LHWAAK G
Sbjct: 258 GG--GSVTLDPLEHAWMLSASDGKWD-SLEGLLTCEPGLLVKRDFITGFTCLHWAAKHGR 314
Query: 359 GEMALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVRLGAQVHVRDHS 418
E+ LV A + PV+++AR+ GGYT LHLAA+HGH + LLV A V +RD+S
Sbjct: 315 QELLAMLVNFANKHQLPVNIDARTSGGYTALHLAAMHGHVEVVKLLVGAYDADVDIRDYS 374
Query: 419 GRRAYQYLRPGSSYALRRLLGDPGLRGTTEPDATGGGSGSLAARRPVQVAATILS 473
G++A QYL + ++ L+G +GGG L+ P + LS
Sbjct: 375 GKKASQYLSRSIAEEIKNLVGALDEGDGESAAGSGGGRWRLSKVLPSHLITYKLS 429
>gi|71274172 ankyrin repeat domain 56 [Homo sapiens]
Length = 793
Score = 136 bits (342), Expect = 6e-32
Identities = 74/178 (41%), Positives = 105/178 (58%), Gaps = 1/178 (0%)
Query: 303 SAVPLEPSEHEWLVRTAGGRWTHQLHGLLLRDRGLAAKRDFMSGFTALHWAAKSGDGEMA 362
S VPL+ EHEW+V+ A G W Q+ L D LA +DF++G+TALHW AK GD
Sbjct: 589 SLVPLDAREHEWIVKLASGSWI-QVWTLFWEDPQLALHKDFLTGYTALHWIAKHGDLRAL 647
Query: 363 LQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVRLGAQVHVRDHSGRRA 422
LV A+++G +DVN RS GYTPLHLAA+HGH+ LLV RL ++V+VRD SG++
Sbjct: 648 QDLVSGAKKAGIVLDVNVRSSCGYTPLHLAAIHGHQGVIKLLVQRLASRVNVRDSSGKKP 707
Query: 423 YQYLRPGSSYALRRLLGDPGLRGTTEPDATGGGSGSLAARRPVQVAATILSSTTSAFL 480
+QYL +S + +LLG P + G S + +++ ++ T+ A L
Sbjct: 708 WQYLTSNTSGEIWQLLGAPRGKPIFPVYPLVGSSSPTRKAKSKEISRSVTRKTSFAAL 765
Score = 74.7 bits (182), Expect = 2e-13
Identities = 67/190 (35%), Positives = 86/190 (45%), Gaps = 19/190 (10%)
Query: 11 AAGVSQAAVLGFLQEHGGKVRNSELLSRFKPLLDAGD--PRGRAARRDRFKQFVNNVAVV 68
A +SQ A+L FL + GG+V N+ LLS FK L D P RR+ FK FVN+VA V
Sbjct: 2 ARELSQEALLDFLCQAGGRVTNAALLSHFKSFLRDPDASPSQHQHRRELFKGFVNSVAAV 61
Query: 69 K-ELDGVKFVVLRKKPRPPEPEPAPFGP--PGAAAQPSKPTSTVLPRSASAPGAPPLV-- 123
+ + DG K+VVL+++ R E P P AAA + + PR A G PP
Sbjct: 62 RQDPDGTKYVVLKRRYRDLLGEEGLQRPREPPAAAPSAGGAAPCSPRGARR-GEPPQQQP 120
Query: 124 ----RVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSAD-------PPLPALELAQ 172
R P E P G P S+ + PG+ PP+PA A
Sbjct: 121 RRRRREKEPEEEPAGAAARAADAACNGLPGSDSRRAPGKGGGSKGSPGQRPPVPAAAAAG 180
Query: 173 ATERPSADAA 182
A R S AA
Sbjct: 181 AQARASCAAA 190
>gi|157743267 ankyrin repeat domain 58 [Homo sapiens]
Length = 315
Score = 125 bits (313), Expect = 1e-28
Identities = 98/279 (35%), Positives = 129/279 (46%), Gaps = 13/279 (4%)
Query: 206 GAAKGPPQQK--PCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEE 263
GAA P P +RC P P R G + + R P ++
Sbjct: 6 GAANRAPTASLAPTSQSLRCAPQPRPSRADTGSLGRYWGKAAAAASREHPF---PGTLMH 62
Query: 264 SGLGLGLGPGRSPHLRRLSRAGPR--LLSPDAEEL--PAAPPPSAVPLEPSEHEWLVRTA 319
S G G G L L RA P L AEEL P+ P S + LEP EH W++ A
Sbjct: 63 SAAGSGRRRGALRELLGLQRAAPAGWLSEERAEELGGPSGPGSSRLCLEPREHAWILAAA 122
Query: 320 GGRWTHQLHGLLLRDRGLAAKRDFMSGFTALHWAAKSGDGEMALQLVEVARRSGAPVDVN 379
GR+ L LL + L + D ++G++ LHW AK G E + + + A R G +DV+
Sbjct: 123 EGRY-EVLRELLEAEPELLLRGDPITGYSVLHWLAKHGRHEELILVHDFALRRGLRLDVS 181
Query: 380 ARSHGGYTPLHLAALHGHEDAAVLLVVRLGAQVHVRDHSGRRAYQYLRPGSSYALRRLLG 439
A GG TPLHLAAL GH+ +LV LGA RDHSG RA YLRP + + LR L G
Sbjct: 182 APGSGGLTPLHLAALQGHDMVIKVLVGALGADATRRDHSGHRACHYLRPDAPWRLRELSG 241
Query: 440 DPGLR---GTTEPDATGGGSGSLAARRPVQVAATILSST 475
G+ + SG+ A R V AT + ++
Sbjct: 242 AEEWEMESGSGCTNLNNNSSGTTAWRAASAVGATAVETS 280
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 78.6 bits (192), Expect = 1e-14
Identities = 77/251 (30%), Positives = 99/251 (39%), Gaps = 31/251 (12%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKP--TSTVLPRSASAPGA--PPLVRVPRPVE------PP 132
P P PE +P PP + S P S + P P + P + + RP+E PP
Sbjct: 439 PLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPP 498
Query: 133 GDLGLPTEPQDTPGGPASE-PAQPPGERSADPPLPALELAQATERPSADAAPP----PRA 187
+ L P+ +P P E P PP E PP PALE + ++ +PP P +
Sbjct: 499 EESPLSPPPESSPFSPLEESPLSPPEE---SPPSPALETPLSPPPEASPLSPPFEESPLS 555
Query: 188 PSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVP-APATLRLRAEEPGLRRQLSEE 246
P P S PP+A PP++ P P P +P R P LS
Sbjct: 556 PPPEELPTSPPPEA----SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPP 611
Query: 247 P--SPRSSPLLLRRLSVEESGLGLGLGPGRSPHL--RRLSRAGP----RLLSPDAEELPA 298
P SP S P RLS + P SP +SR P LSP EE P
Sbjct: 612 PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Query: 299 APPPSAVPLEP 309
+PPP P P
Sbjct: 672 SPPPEESPTSP 682
Score = 67.8 bits (164), Expect = 2e-11
Identities = 71/243 (29%), Positives = 88/243 (36%), Gaps = 52/243 (21%)
Query: 79 LRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAP-GAPPLVRVPRPVEPPGDLGL 137
L + P P PE +P PP S P S + S P +PP + P+ PP
Sbjct: 489 LEESPLSPPPEESPLSPP----PESSPFSPLEESPLSPPEESPPSPALETPLSPP----- 539
Query: 138 PTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPR----APSEAAS 193
P + P PP E S P P EL + ++ +PPP +P S
Sbjct: 540 ----------PEASPLSPPFEESPLSP-PPEELPTSPPPEASRLSPPPEESPMSPPPEES 588
Query: 194 PCSDPPDA-------EPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEE 246
P S PP+A E P PP++ P P P RL E
Sbjct: 589 PMSPPPEASRLFPPFEESP--LSPPPEESPLS------PPPEASRLSPPPEDSPMSPPPE 640
Query: 247 PSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVP 306
SP S P + RLS L P SP LSP EE P +PPP A
Sbjct: 641 ESPMSPPPEVSRLSPLPVVSRLSPPPEESP------------LSPPPEESPTSPPPEASR 688
Query: 307 LEP 309
L P
Sbjct: 689 LSP 691
Score = 63.9 bits (154), Expect = 4e-10
Identities = 68/233 (29%), Positives = 86/233 (36%), Gaps = 61/233 (26%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTE 140
K+P P + E P G G +P P + P PP P+ PP P E
Sbjct: 407 KEPGPLQCEAKPLGKAGVQLEPQLEA----PLNEEMPLLPPPEE--SPLSPP-----PEE 455
Query: 141 PQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPD 200
+P AS + PP E A P AL L++ E + +PPP SP S PP+
Sbjct: 456 SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEE--SPLSPPPEE-----SPLSPPPE 508
Query: 201 AEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLS 260
+ P P ++ P P P+PA L LS P P +SPL
Sbjct: 509 SSPF-----SPLEESPLSPPEESPPSPA----------LETPLS--PPPEASPL------ 545
Query: 261 VEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEPSEHE 313
SP LSP EELP +PPP A L P E
Sbjct: 546 --------------SPPFEESP------LSPPPEELPTSPPPEASRLSPPPEE 578
Score = 61.2 bits (147), Expect = 2e-09
Identities = 72/247 (29%), Positives = 87/247 (35%), Gaps = 50/247 (20%)
Query: 85 PPEPEPAPFGPPGA---AAQPSKPTSTVLPRSASAPG-----APPLVRVPRPVEPPGDLG 136
PPEP P P A A Q V PG A PL + +EP +
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 137 LPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAP-----------PP 185
L E P S + PP E PP A L+ E A P P
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESP 493
Query: 186 RAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSE 245
+P SP S PP++ P P ++ P P P+PA L LS
Sbjct: 494 LSPPPEESPLSPPPESSP-----FSPLEESPLSPPEESPPSPA----------LETPLS- 537
Query: 246 EPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGP---RLLSPDAEELPAAPPP 302
P P +SPL EES L SP L + P LSP EE P +PPP
Sbjct: 538 -PPPEASPL---SPPFEESPL--------SPPPEELPTSPPPEASRLSPPPEESPMSPPP 585
Query: 303 SAVPLEP 309
P+ P
Sbjct: 586 EESPMSP 592
Score = 60.5 bits (145), Expect = 4e-09
Identities = 73/253 (28%), Positives = 95/253 (37%), Gaps = 37/253 (14%)
Query: 76 FVVLRKKPRPPEPEPAPFGPPGAAAQPSKPT--STVLPRSASAPGAPP--------LVRV 125
F + P P PE +P PP A++ S P S + P +P +PP L V
Sbjct: 600 FPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVV 659
Query: 126 PRPVEPPGDLGLPTEPQDTPGGP---ASEPAQPPGERSADPPLPALELAQATERPSADAA 182
R PP + L P+++P P AS + PP + PP P A
Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP------------PEDSPA 707
Query: 183 PPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQ 242
PP S + P + P P P + P+ + L R P L R EEP L Q
Sbjct: 708 SPPPEDSLMSLPLEESP-LLPLPEEPQLCPRSEGPHLSPR--PEEPHLSPRPEEPHLSPQ 764
Query: 243 LSEEP--SPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAP 300
+EEP SP+ L + E GP SP L LSP EE +P
Sbjct: 765 -AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH------LSPQTEEPHLSP 817
Query: 301 PPSAVPLEPSEHE 313
P L P E
Sbjct: 818 VPEEPCLSPQPEE 830
Score = 60.5 bits (145), Expect = 4e-09
Identities = 75/256 (29%), Positives = 91/256 (35%), Gaps = 43/256 (16%)
Query: 83 PRPPEPEPAPFGPPGAAAQ--PSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTE 140
P P PE +P PP ++ P S + P +P +PP P PP L
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTS-PPPEASRLSPP 692
Query: 141 PQDTPGGPASE--PAQPPGERSA-------DPPLPALELAQATERPSADAAPP------- 184
P+D+P P E PA PP E S P LP E Q R P
Sbjct: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHL 752
Query: 185 -PRAPSEAASPCSDPPDAEPGPG-----AAKGPPQQKPCMLPVRCVPAPATLRL--RAEE 236
PR SP ++ P P P A P P P P L L + EE
Sbjct: 753 SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEE 812
Query: 237 PGLRRQLSEEPSPRSSPLLLRRLSVEESGLG-LGLGPGRSPHLRRLSRAGPRLLSPDAEE 295
P L + EEP P EES L P SP R LSP+ E+
Sbjct: 813 PHLS-PVPEEPCLSPQP--------EESHLSPQSEEPCLSP------RPEESHLSPELEK 857
Query: 296 LPAAPPPSAVPLEPSE 311
P +P P P EP +
Sbjct: 858 PPLSPRPEKPPEEPGQ 873
Score = 60.1 bits (144), Expect = 5e-09
Identities = 73/242 (30%), Positives = 93/242 (38%), Gaps = 29/242 (11%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQPSKPT--STVLPRSASAPGAPPLVR--VPRPVEPPGDLG 136
+ P P PE +P PP A++ S P S P +P +PP + P+E L
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727
Query: 137 LPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAA---- 192
LP EPQ P + P E P L+ E P +P P P A
Sbjct: 728 LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHL--SPQPEEPCLCAVPEE 785
Query: 193 ---SPCSDPPDAEPGPGAAKGPPQ-QKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPS 248
SP ++ P P P PQ ++P + PV P L + EE L Q SEEP
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPV---PEEPCLSPQPEESHLSPQ-SEEPC 841
Query: 249 PRSSPLLLRRLSVEESGLGLGLG-PGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPL 307
P EES L L P SP + + +P EELP PPP L
Sbjct: 842 LSPRP--------EESHLSPELEKPPLSPRPEKPPEEPGQCPAP--EELPLFPPPGEPSL 891
Query: 308 EP 309
P
Sbjct: 892 SP 893
Score = 50.1 bits (118), Expect = 5e-06
Identities = 69/235 (29%), Positives = 83/235 (35%), Gaps = 43/235 (18%)
Query: 82 KPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEP 141
K P P PFG A + K L S+ + G P L V P GL +
Sbjct: 2267 KASEPLLSPPPFGESRKALEVKKEE---LGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
Query: 142 QD------TPGGPASEPAQPP-GERSADPPLPALELAQATERPSADAAPPPRAPSEAASP 194
D TP EP P G R +PP PA LA PS + P P P
Sbjct: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQEPP-PAQALA-----PSPPSHPDIFRPGSYTDP 2377
Query: 195 CSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPL 254
+ PP P P + PP + C LP R +P+ R+ A + S SPL
Sbjct: 2378 YAQPP-LTPRP---QPPPPESCCALPPRSLPSDPFSRVPAS--------PQSQSSSQSPL 2425
Query: 255 LLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEP 309
R LS E P S PR SPD P + P S P P
Sbjct: 2426 TPRPLSAE------AFCP---------SPVTPRFQSPDPYSRPPSRPQSRDPFAP 2465
Score = 49.3 bits (116), Expect = 9e-06
Identities = 64/230 (27%), Positives = 82/230 (35%), Gaps = 50/230 (21%)
Query: 92 PFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPASE 151
P+ PG P + P+ PG P +LG PQ P PA
Sbjct: 4242 PYQEPGTQTSPLQGLLGCQPQLGGFPGPQ--------TGPLQELGAGPRPQGPPRLPA-- 4291
Query: 152 PAQPPGERSADP------PLPALELAQATERPSADAAPPPRAPSEAASPCSDP------- 198
PPG S P P P Q +RPS +P + P+EA P + P
Sbjct: 4292 ---PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
Query: 199 PDAEPGPGA-------------AKG-PPQQKPCMLPVRCVPAPATL------RLRAEEPG 238
P EP PG +KG P P L P ++L ++ +
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVP 4408
Query: 239 LRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLG-PGRSPHLRRLSRAGPR 287
QLS + PR P L SV+ G +G PG S H L AGPR
Sbjct: 4409 EASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNH---LLLAGPR 4455
Score = 47.8 bits (112), Expect = 3e-05
Identities = 83/310 (26%), Positives = 103/310 (33%), Gaps = 83/310 (26%)
Query: 78 VLRKKPRPP-----EPEPAPFGPPGAAAQP-----SKPTSTVLPRSASAPGAPPLVRVPR 127
+ RK RP P+P G P AA P S T L SA PP VP
Sbjct: 2093 IARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152
Query: 128 PVEPPGDLGLPTEPQDTPGGPASEPAQPP-GERSADPPLPALELAQATERP-SADAAPPP 185
P + PG+L L PQ PA P+Q P G A P P A T P + P
Sbjct: 2153 P-DSPGELFLKLPPQV----PAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPA 2207
Query: 186 RAPSEAASPCSDPPDAEPG------PGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGL 239
+ P AS S P +PG PG + P L RC P+ L + E PG+
Sbjct: 2208 QPPMLGAS--SRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRC-PSLDNLAV-PESPGV 2263
Query: 240 RRQLSEEP-------------------------------------SPRS----------- 251
+ EP SP S
Sbjct: 2264 GGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
Query: 252 -----SPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPR---LLSPDAEELPAAPPPS 303
+PL R VE GLGL P P + L+ + P + P + P A PP
Sbjct: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383
Query: 304 AVPLEPSEHE 313
+P E
Sbjct: 2384 TPRPQPPPPE 2393
Score = 47.0 bits (110), Expect = 5e-05
Identities = 64/236 (27%), Positives = 80/236 (33%), Gaps = 41/236 (17%)
Query: 79 LRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLP 138
L K P P PE PP Q P L P PL+ P EP G+ L
Sbjct: 855 LEKPPLSPRPEK----PPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP-GEPPLS 909
Query: 139 TEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAP--SEAASPCS 196
P++ P P+ EP+ P DP PPP +P + AA P
Sbjct: 910 PLPEELPLSPSGEPSLSPQLMPPDP------------------LPPPLSPIITAAAPPAL 951
Query: 197 DPPDAEPGPGAAKGPPQ-QKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRS---- 251
P P AKG + P P+ P +P + PSP S
Sbjct: 952 SPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP 1011
Query: 252 -SPLLLRRLSVEESG-LGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAV 305
SP+L+ L + S L L P SP P SP A L P S +
Sbjct: 1012 ASPILMEPLPPQCSPLLQHSLVPQNSP---------PSQCSPPALPLSVPSPLSPI 1058
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/179 (28%), Positives = 65/179 (36%), Gaps = 23/179 (12%)
Query: 79 LRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLP 138
L +P+PP PE PP + PS P S V P S + + PRP+ P
Sbjct: 2383 LTPRPQPPPPESCCALPPRSL--PSDPFSRV-PASPQSQSSSQSPLTPRPLSAEAFCPSP 2439
Query: 139 TEPQDTPGGPASEPAQPPGERSA-----DPPLP--------ALELAQATERPSADAAPPP 185
P+ P S P P R PP P A LA + A P
Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALP 2499
Query: 186 RAPS---EAASPCSDPPD--AEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGL 239
P+ A P PP+ PG GA G P P + V P +L+ +PGL
Sbjct: 2500 AGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFP-QAVGEP-SLKPPVPQPGL 2556
Score = 37.7 bits (86), Expect = 0.027
Identities = 35/130 (26%), Positives = 41/130 (31%), Gaps = 14/130 (10%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRV--------PRPVEPPG- 133
P P EP P P GP + P PG P R P + P G
Sbjct: 2862 PGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGL 2921
Query: 134 ----DLGLPTEPQDTPGGPASEPAQPPGERSADPPLPA-LELAQATERPSADAAPPPRAP 188
GLP + P P + P + P LP LEL + P P A
Sbjct: 2922 RGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLAL 2981
Query: 189 SEAASPCSDP 198
PC DP
Sbjct: 2982 EAGKLPCEDP 2991
Score = 37.4 bits (85), Expect = 0.036
Identities = 43/174 (24%), Positives = 60/174 (34%), Gaps = 46/174 (26%)
Query: 83 PRPPEPEP---APFGPPGAA--AQPSKPTSTVLPRSASAPGAP--PLVRVPRPVEPPGDL 135
P P P P PP A P +LP S +P P P++ P P + L
Sbjct: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLL 1028
Query: 136 GLPTEPQDTPGGPASEPAQPPG-------------------------ERSADPPLPALEL 170
PQ++P S PA P E+ ++P PALE
Sbjct: 1029 QHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEP 1088
Query: 171 AQATERPS--ADAAPPPRAPSEAASPCS------------DPPDAEPGPGAAKG 210
+ + PS D + P +P+ A S D P ++P PG G
Sbjct: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPG 1142
Score = 33.5 bits (75), Expect = 0.52
Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 13/71 (18%)
Query: 138 PTEPQDTPGGPASEPAQP--------PGERSADPPLPA-LELAQATERPSADAAPPPRAP 188
P EP P A PA P P E A+PP+P+ L LA + E A P PRA
Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPE----SARPKPRAR 4966
Query: 189 SEAASPCSDPP 199
S PP
Sbjct: 4967 PPEEGEDSRPP 4977
Score = 32.3 bits (72), Expect = 1.2
Identities = 24/87 (27%), Positives = 35/87 (40%), Gaps = 10/87 (11%)
Query: 79 LRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLP 138
+R+ PP EP+P P A + S PT ++ PP+ P L L
Sbjct: 4903 VRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPV---------PSPLPLA 4953
Query: 139 TEPQDTPGGPASEPAQPPGERSADPPL 165
+ P+ P + P + GE S P L
Sbjct: 4954 SSPESARPKPRARPPE-EGEDSRPPRL 4979
Score = 32.0 bits (71), Expect = 1.5
Identities = 27/104 (25%), Positives = 41/104 (39%), Gaps = 19/104 (18%)
Query: 150 SEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAK 209
S +PP + S + L++ Q + APPP PS SP + P + P +
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLS-------APPPEEPSPPPSPLAPSPASPPTEPLVE 4935
Query: 210 GPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSP 253
P + P+ P P+ L L + R P PR+ P
Sbjct: 4936 LPTE------PLAEPPVPSPLPLASSPESAR------PKPRARP 4967
Score = 31.2 bits (69), Expect = 2.6
Identities = 53/195 (27%), Positives = 64/195 (32%), Gaps = 48/195 (24%)
Query: 76 FVVLRKKPRPPEPEPA--------------------PFGPPGAAAQPSKPTSTVLPRSAS 115
F L K PRP PE A P GP G +K S P
Sbjct: 2463 FAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGEL--HAKVPSGQPPNFVR 2520
Query: 116 APGAPPLVRVPRPVE--PPGDLGLPTEPQDTPGGPASEPAQPP--GERSADPPLPALELA 171
+PG V P P+ P +G EP P P +P PP G S P P L
Sbjct: 2521 SPGTGAFVGTPSPMRFTFPQAVG---EPSLKP--PVPQPGLPPPHGINSHFGPGPTLGKP 2575
Query: 172 QATERPSADA----APPPRAPSEAAS-----------PCSDPPDAEPG--PGAAKGPPQQ 214
Q+T A + P PS ++ P PP A G P + G Q+
Sbjct: 2576 QSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQR 2635
Query: 215 KPCMLPVRCVPAPAT 229
PV P T
Sbjct: 2636 SGITSPVEKREDPGT 2650
Score = 31.2 bits (69), Expect = 2.6
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 8/76 (10%)
Query: 148 PASEPAQPPGERSADPPLPALE-LAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPG 206
P EP+ PP + P P E L + P A+ PP +P A S P A P P
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAE--PPVPSPLPLA---SSPESARPKPR 4964
Query: 207 AAKGPPQQKPCMLPVR 222
A PP++ P R
Sbjct: 4965 AR--PPEEGEDSRPPR 4978
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 73.9 bits (180), Expect = 3e-13
Identities = 79/253 (31%), Positives = 104/253 (41%), Gaps = 45/253 (17%)
Query: 77 VVLRKKPRPPEPEP---APFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPG 133
V L + P P P P APF PP A+ P P++T ++ + APPL P P P
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715
Query: 134 DLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAAS 193
T P P A+ P Q P A PP+ S A PPPR P A+
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPM------------SPSATPPPRVPPLLAA 763
Query: 194 P----CSDPPDAEPGPGAAKGPPQQKPCML--PVRCVPA-PATLRLRAE-EPGLRRQLS- 244
P PP + P AK PPQ P + P++ +P+ PA+ +A P +S
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823
Query: 245 -EEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSR----------AGPRLLSPDA 293
P P++ P+L L L + P SP L+ R +GPRL A
Sbjct: 824 LATPPPQAPPVLAAPL------LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877
Query: 294 EELPAAPPPSAVP 306
P PPPS P
Sbjct: 878 PGPP--PPPSRSP 888
Score = 71.2 bits (173), Expect = 2e-12
Identities = 72/238 (30%), Positives = 92/238 (38%), Gaps = 24/238 (10%)
Query: 85 PPEPEPAPFGPP--GAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQ 142
PP+ PA PP G + P P +T P++ PPL P P P L T
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
Query: 143 DTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASP----CSDP 198
P A Q P PP+ A A+ S A PP +AP A+P P
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 199 PDAEPGPGAAKGPPQQKPCML--PVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLL 256
P + P +A PPQ P + P++ P+P A P S P PR PLL
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPP-----ASPP---MSPSATPPPRVPPLLA 762
Query: 257 R-RLSVEES-GLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPP--PSAVPLEPS 310
L V S L + P P +A P L +P + LP+ P P P PS
Sbjct: 763 APPLQVPPSPPASLPMSPLAKPP----PQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Score = 64.7 bits (156), Expect = 2e-10
Identities = 68/227 (29%), Positives = 89/227 (39%), Gaps = 36/227 (15%)
Query: 102 PSKPTSTVLPRSASAPGA----PPLVRVPRPVEPP---GDLGLPTEPQDTPGGPASEPAQ 154
P + S++ P S P A PPL +P PP L T +TP PA P Q
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQ 570
Query: 155 PPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQ 214
P PP E PS+ A PPP+AP ASP + P A PPQ
Sbjct: 571 APPSPLTTPP---------PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 215 KPCML--PVRCVPAP---------ATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEE 263
P + P++ P+P AT +A L SP SP + S
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 264 SGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEPS 310
S P SP S+A P L +P + P+ PP++ P+ PS
Sbjct: 682 S-------PPVSPSATPPSQAPPSLAAPPLQVPPS--PPASPPMSPS 719
Score = 63.2 bits (152), Expect = 6e-10
Identities = 74/248 (29%), Positives = 92/248 (37%), Gaps = 51/248 (20%)
Query: 85 PPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLP------ 138
PP P P P P PS P +T P + S+ PP P PP GLP
Sbjct: 561 PPCPAPCPLQAP-----PS-PLTTPPPETPSSIATPPPQAPPALASPPLQ-GLPSPPLSP 613
Query: 139 --TEPQDTPGGPASEPAQPPGERSADPPL-------PALELAQATERPSADAAPPPRAPS 189
T P P A P Q P A PPL P A A A +PPP P
Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673
Query: 190 EA--ASPCSDP--PDAEP---GPGAAKGPPQQKPCMLPVRCVPAP-ATLRLRAEEPGLRR 241
+A + P S P P A P P + PP Q P P +P AT +A P
Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733
Query: 242 QLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPP 301
L PSP +SP + SP R P L +P + P+ P
Sbjct: 734 PLQVPPSPPASPPM-------------------SPSATPPPRVPPLLAAPPLQVPPS--P 772
Query: 302 PSAVPLEP 309
P+++P+ P
Sbjct: 773 PASLPMSP 780
Score = 61.6 bits (148), Expect = 2e-09
Identities = 71/245 (28%), Positives = 88/245 (35%), Gaps = 36/245 (14%)
Query: 82 KPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPP-LVRVPRPVEPPGDLGLPTE 140
K RP P P A PS P +T LP + +P APP L +P P P
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP-------- 364
Query: 141 PQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPS--EAASPCSDP 198
P P + P Q P PP +++ + PS A P P A S +A + P
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPP---IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421
Query: 199 P--------DAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPR 250
P A +P P P A L L A P L+ LS SP
Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPP-LQTSLSPAVSPL 480
Query: 251 SSPLLLRRL----SVEESGLGLGLGPGRSPHLRRLSRAGP--------RLLSPDAEELPA 298
SSPL + L S+ L P L S P L +P E LP+
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
Query: 299 -APPP 302
APPP
Sbjct: 541 LAPPP 545
Score = 45.4 bits (106), Expect = 1e-04
Identities = 67/246 (27%), Positives = 84/246 (34%), Gaps = 30/246 (12%)
Query: 87 EPEPAPFGPPGAAAQPSKPTSTVLPRSA--------SAPGAPPLVRVPRPVEPPGDLGLP 138
EP PA P A +P S L SA S P A R P P GL
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 139 T--EPQDTPGGPASEPAQPPGERSADP---PLPALELAQATERPSADAAPPPRAPSEAAS 193
PQ TP P + A G S+ P P P+ A+ P A P P A +
Sbjct: 279 ALRPPQVTP--PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLP-ATLPPSP 335
Query: 194 PCSDP-PDAEPGPGAAKG----------PPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQ 242
P + P P A P P A PP Q P + + AP +L+
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395
Query: 243 LSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPP 302
S SPL L L S LG ++ H S + PA+ PP
Sbjct: 396 TSPSLQAPPSPLALSSLQATTS---LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 303 SAVPLE 308
+ PL+
Sbjct: 453 DSPPLQ 458
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/233 (22%), Positives = 75/233 (32%), Gaps = 15/233 (6%)
Query: 90 PAPFGPPGAAAQPSKPTSTVLPRSASAPG----APPLVRVPRPVEPPGDLGLPTEPQDTP 145
PA PG + P + + T P G A V + E P L +
Sbjct: 105 PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164
Query: 146 GGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGP 205
GP P P + E+ PSA PP P ++ S S+ EP P
Sbjct: 165 SGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222
Query: 206 GAAKGPPQ----QKPC--MLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRR- 258
A + P Q+P L P + R G R + P+ L R
Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 259 --LSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEP 309
++ LGP S L S +G + + A P P+ +P P
Sbjct: 283 PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335
Score = 45.1 bits (105), Expect = 2e-04
Identities = 59/223 (26%), Positives = 72/223 (32%), Gaps = 34/223 (15%)
Query: 65 VAVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTV--LPRSASAPGAPPL 122
VA K + K L R P P P A A+ S+ T LPR A + P
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
Query: 123 VRVPRPVEPPGDLGLPTEP------QDTPGGPASEPAQPPGERSADP---PLPALELAQA 173
PR TEP + + GG PA SA P P + A+
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 174 TERPSA----------------DAAPPPRAPSEAASPCSDPPDAEPGPGAAKG----PPQ 213
T R A PP + + A P S P A P P K PP
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 214 QKPCMLPVRCVPAP---ATLRLRAEEPGLRRQLSEEPSPRSSP 253
LP P+P L L P L PSP ++P
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATP 364
Score = 43.5 bits (101), Expect = 5e-04
Identities = 73/246 (29%), Positives = 88/246 (35%), Gaps = 63/246 (25%)
Query: 79 LRKKPRPPE--PEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLG 136
L+ P PP P APF P +A+ P P +T P++ AP L P P P L
Sbjct: 797 LQALPSPPASFPGQAPFSP--SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP-TLQ 853
Query: 137 LPTEPQDTPG----------------GPASEPAQPPGERSADPPLPALELAQATERP--- 177
P P TPG GP P++ P + P L A + AT P
Sbjct: 854 APRRP-PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTPEEL 911
Query: 178 ---------SADAAPPPRAPSEAASPCS-----DPPDAEPG-PGA-AKGPPQQKPCMLPV 221
A A+PPP A A P + PP A G PGA PP P
Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971
Query: 222 RCV------PAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRS 275
C P AT A +PG PSP +S +G G G RS
Sbjct: 972 LCTIYETEGPESATPAPGALDPG--------PSPGTSG------GKAAAGAGAG-ASSRS 1016
Query: 276 PHLRRL 281
P RL
Sbjct: 1017 PKQARL 1022
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 66.6 bits (161), Expect = 6e-11
Identities = 72/242 (29%), Positives = 89/242 (36%), Gaps = 65/242 (26%)
Query: 79 LRKKPRPPEPEPAPFGPPGAA-----AQPSKPTSTVL-PRSASAPGAPPLVRV---PRPV 129
L P P P P PP A A PS P S L P + +P AP + V P
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 440
Query: 130 EPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPP--LPALELAQATERPSADAAPPPRA 187
PP P+ P P P PA PP SA PP P A + P + A PP +
Sbjct: 441 SPP-----PSPPVQAPFSP---PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492
Query: 188 PSEAASPCSDPPDAEPGPGAAKGPPQQKPCML--PVRCVPAPATLRLRAEEPGLRRQLSE 245
PS P + PP A P AK PPQ P + P++ +P+P
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP------------------ 534
Query: 246 EPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAV 305
P S P G++P S + +SP A P APP A
Sbjct: 535 ---PASFP-------------------GQAP----FSPSASLPMSPLATPPPQAPPVLAA 568
Query: 306 PL 307
PL
Sbjct: 569 PL 570
Score = 60.8 bits (146), Expect = 3e-09
Identities = 68/206 (33%), Positives = 82/206 (39%), Gaps = 31/206 (15%)
Query: 77 VVLRKKPRPPEPEP---APFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPG 133
V L + P P P P APF PP A+ P P++T ++ + APPL P P P
Sbjct: 433 VHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP- 489
Query: 134 DLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAAS 193
P P TP A P P + A PP P A AT P A P P A +
Sbjct: 490 ----PMSPSATPPPQAPPPLAAPPLQLAKPP-PQAPPALAT--PPLQALPSPPASFPGQA 542
Query: 194 PCSDPPDAEPGPGAAKGPPQQKPCM-LPVRCVP--APATLRLRAEEPGLRRQLSEEPSPR 250
P S P + P A PPQ P + P+ VP PA+ L+A PR
Sbjct: 543 PFS-PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA--------------PR 587
Query: 251 SSPLLLRRLSVEESGLGLGLGPGRSP 276
P SV L L L PG P
Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPPP 613
Score = 58.5 bits (140), Expect = 2e-08
Identities = 78/277 (28%), Positives = 101/277 (36%), Gaps = 57/277 (20%)
Query: 79 LRKKPRPPEPEPAP----FGPPGAAAQ-------PSKPTSTVLPRSASAPGAPPLVRVPR 127
L+ P PP P+ G P A P P +T P++ A PPL P
Sbjct: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410
Query: 128 PVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRA 187
P P L T P A Q P PP+ A A+ S A PP +A
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470
Query: 188 PSEAA----------------SPCSDPPDAEPGPGA------AKGPPQQKPCML--PVRC 223
P A SP + PP P P A AK PPQ P + P++
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 530
Query: 224 VPA-PATLRLRAE-EPGLRRQLS--EEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLR 279
+P+ PA+ +A P +S P P++ P+L L L + P SP L+
Sbjct: 531 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL------LQVPPSPPASPTLQ 584
Query: 280 RLSR----------AGPRLLSPDAEELPAAPPPSAVP 306
R +GPRL A P PPPS P
Sbjct: 585 APRRPPTPGPDTSVSGPRLTLALAPGPP--PPPSRSP 619
Score = 55.5 bits (132), Expect = 1e-07
Identities = 70/257 (27%), Positives = 95/257 (36%), Gaps = 45/257 (17%)
Query: 85 PPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDT 144
P P+ G P A A PS+P P+ A PP V PR P L + P T
Sbjct: 252 PARSGPSARGTPRAPAHPSQPK----PKGLQAL-RPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 145 PGGPASEPAQPPGERSADPPLPALELAQATERPSADAAP--PPRAPSEAASPCSDPPDAE 202
P A+ +Q P A P +L AT P A +P PP + + P + P A
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366
Query: 203 PGPGA------------------AKGPPQQKPCML--PVRCVPAP---------ATLRLR 233
G+ A PPQ P + P++ P+P AT +
Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426
Query: 234 AEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDA 293
A L SP SP + S S P SP S+A P L +P
Sbjct: 427 APNALAVHLLQAPFSPPPSPPVQAPFSPPAS-------PPVSPSATPPSQAPPSLAAPPL 479
Query: 294 EELPAAPPPSAVPLEPS 310
+ P+ PP++ P+ PS
Sbjct: 480 QVPPS--PPASPPMSPS 494
Score = 50.8 bits (120), Expect = 3e-06
Identities = 65/230 (28%), Positives = 83/230 (36%), Gaps = 16/230 (6%)
Query: 87 EPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPG 146
EP PA P A +P S L SA+ P + P P P P++P+
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRSLSSSAT-PLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 147 GPASEPAQPPGERSADPPL-PALELAQATERPSA---DAAPP--PRAPSEAASPCSDPPD 200
P P + A P L P AT PSA APP P P ++ C
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP 337
Query: 201 AEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLS 260
P + PP + P P+ AT L + P L+ S PSP SPL
Sbjct: 338 LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS--PTLQATHSFLPSPPLSPLATPPPQ 395
Query: 261 VEES----GLGLGLGPGRSPHLRRL---SRAGPRLLSPDAEELPAAPPPS 303
+ L P SP L L S P L+ + P +PPPS
Sbjct: 396 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 445
Score = 47.4 bits (111), Expect = 3e-05
Identities = 73/262 (27%), Positives = 89/262 (33%), Gaps = 20/262 (7%)
Query: 65 VAVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTV--LPRSASAPGAPPL 122
VA K + K L R P P P A A+ S+ T LPR A + P
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
Query: 123 VRVPRPVEPPGDLGLPTEP------QDTPGGPASEPAQPPGERSADP---PLPALELAQA 173
PR TEP + + GG PA SA P P + A+
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 174 TER-PSADAAPPPRAPSEAASPCSDPP--DAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
T R P+ + P P+ P PP DA P G P P AP TL
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321
Query: 231 RLRAEEPGLRRQLS-----EEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAG 285
L QL+ PSP + P L S + SP L+
Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 381
Query: 286 PR-LLSPDAEELPAAPPPSAVP 306
P LSP A P APP A+P
Sbjct: 382 PSPPLSPLATPPPQAPPALALP 403
Score = 42.4 bits (98), Expect = 0.001
Identities = 51/219 (23%), Positives = 70/219 (31%), Gaps = 16/219 (7%)
Query: 90 PAPFGPPGAAAQPSKPTSTVLPRSASAPG----APPLVRVPRPVEPPGDLGLPTEPQDTP 145
PA PG + P + + T P G A V + E P L +
Sbjct: 105 PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164
Query: 146 GGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGP 205
GP P P + E+ PSA PP P ++ S S+ EP P
Sbjct: 165 SGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222
Query: 206 GAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESG 265
A + P + PA+ L + L PS R +P R +
Sbjct: 223 AARRRPSAGGG-------LQRPASRSLSSSATPLSSPARSGPSARGTP---RAPAHPSQP 272
Query: 266 LGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSA 304
GL R P + + L P + A P PSA
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 311
Score = 42.4 bits (98), Expect = 0.001
Identities = 69/231 (29%), Positives = 76/231 (32%), Gaps = 60/231 (25%)
Query: 83 PRPPEPEPAPFGPPGAAAQ-----PSKPTSTVL--PRSASAPGAPPLVRVPR-------- 127
P P P P PP AA PS P S L PR PG V PR
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
Query: 128 PVEPPGDLGLPTEPQDTPGGP---------ASEPAQ-------PPGERSADPPLPALELA 171
P PP P T GP S P + P G +A PP P ELA
Sbjct: 611 PPPPPS-----RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP-PDAELA 664
Query: 172 QATERP-SADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
S APP +P PP GPG+A G P PAP L
Sbjct: 665 ACHPAAWSRGPAPPLAFRGAPGAPLPWPP--ATGPGSADGLCTIYETEGPESATPAPGAL 722
Query: 231 RLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRL 281
+PG PSP +S +G G G RSP RL
Sbjct: 723 -----DPG--------PSPGTSG------GKAAAGAGAG-ASSRSPKQARL 753
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 66.2 bits (160), Expect = 7e-11
Identities = 73/270 (27%), Positives = 97/270 (35%), Gaps = 57/270 (21%)
Query: 69 KELDGVKFVVLRKKPRPPEPEPAPFGPPGAAA-----------------QPSKPTSTVLP 111
KE K V P+ PAP G P A P PT+T+L
Sbjct: 1476 KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS 1535
Query: 112 RSASAPGA------PPLVRVPRPVEPPGDLGLPTEPQDTPGGPASE-----PAQPPGERS 160
+ A A PP + VP P + P +PT P++ P P+S+ PA P
Sbjct: 1536 KKTPATLAPKEALIPPAMTVPSPKKTP---AIPT-PKEAPATPSSKEASSPPAVTPSTYK 1591
Query: 161 ADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPG--AAKGPPQQKP-- 216
P L + A PS AP P P PP E GP A KG P P
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTP--------PAVTPPSPEKGPATPAPKGTPTSPPVT 1643
Query: 217 --CMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGR 274
+ PA T ++ A P Q S+ + P L+ + V + P
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVP----QASKGLPAKKGPTALKEVLVAPA-------PES 1692
Query: 275 SPHLRRLSRAGPRLLSPDAEELPAAPPPSA 304
+P + +R GP+ A P P PSA
Sbjct: 1693 TPIITAPTRKGPQTKKSSATSPPICPDPSA 1722
Score = 63.2 bits (152), Expect = 6e-10
Identities = 66/240 (27%), Positives = 81/240 (33%), Gaps = 29/240 (12%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPV---EPPGDLGLPT 139
P P P+ AP P AA PS P AP PP P P P G PT
Sbjct: 931 PASPSPKGAP--TPPAATPPSPKGGPATPSPKWAP-TPPAATPPSPKGGPATPSPKGAPT 987
Query: 140 EPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPP 199
P TP P PA P + + PP A P A P + P + PP
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPP------AVTPPSPKGSPAATPFPKGASTPPAATPP 1041
Query: 200 DAEPGPGAA---KGPPQQKPCMLPVRCVPAPATLRLR------AEEPGLRRQLSEEPSPR 250
+ P A KG P LP PAT L+ A P + PSP+
Sbjct: 1042 SPKGSPAATPLPKGAPTTPAATLP-SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100
Query: 251 SSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEPS 310
+P+ G G PH + + P P + A PPP P P+
Sbjct: 1101 GAPMPPAATPPSPKG-----GLATPPH--KGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Score = 63.2 bits (152), Expect = 6e-10
Identities = 67/276 (24%), Positives = 91/276 (32%), Gaps = 54/276 (19%)
Query: 86 PEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGA------------PPLVRVPRP--VEP 131
P P+ AP P P +T P+ A P A PP P P V P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 132 PG---------DLGLPTEPQDTPGGPASEPAQPPGERSADPP----------------LP 166
P G PT P TP P P PP + + PP P
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354
Query: 167 ALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPG--AAKGPPQQKPCMLPVRCV 224
+ + T PP PS P PP + GP + KG P P ++P+
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP-TSPAVIPLSPK 1413
Query: 225 PAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGR--SPHLRRLS 282
APAT R E + P +P+ L++ + G P P L ++
Sbjct: 1414 KAPATPVTR--EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 283 RAGPR--------LLSPDAEELPAAPPPSAVPLEPS 310
P+ S ++ PA P P P P+
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507
Score = 62.0 bits (149), Expect = 1e-09
Identities = 70/261 (26%), Positives = 89/261 (34%), Gaps = 50/261 (19%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAP-------------------PLV 123
P P P+ AP P AA PS P AP P P
Sbjct: 1094 PATPSPKGAPMPP--AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151
Query: 124 RVPRPVEPPGDL------GLPTEPQDTPGGPASEPAQP-----PGERSADPPLPALELAQ 172
P P G L G PT P TP P A P P +A PP P LA
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211
Query: 173 ATER--PSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
+ + P+ AA PP A+P P A P A P+ P P + P P
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATP--SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA- 1268
Query: 231 RLRAEEPGLRRQLSEEPSPRS-SPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLL 289
A P L+ L+ P + +P ++ S + GP SP + + P
Sbjct: 1269 ---ATPPSLKGGLATPPHKGAPNPAVVTPPSPKG-------GPATSP--PKGAPTPPAAT 1316
Query: 290 SPDAEELPAAPPPSAVPLEPS 310
P + P PPP P P+
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPA 1337
Score = 61.2 bits (147), Expect = 2e-09
Identities = 73/237 (30%), Positives = 85/237 (35%), Gaps = 25/237 (10%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLP---- 138
P P P+ AP P AA PS P AP PP V P P P P
Sbjct: 977 PATPSPKGAP--TPPAATPPSPKGGPATPSPKGAP-TPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 139 TEPQDTPGGPASEPAQPPGERSADPPLPALELAQ---ATERPSADAAPPPRA---PSEAA 192
T P TP P PA P + A P PA L PS AP P A PS
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGA-PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092
Query: 193 SPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSS 252
P + P P P AA PP K + AP T A P + P P+ +
Sbjct: 1093 GPATPSPKGAPMPPAAT-PPSPKGGLATPPHKGAPTT---PAATPPSPKGGLATPPPKGA 1148
Query: 253 PLLLRRLSVEESGLGLGLGPGR-SPHLRRLSRAGPR--LLSPD---AEELPAAPPPS 303
P G GL P + +P + P+ L +P A PAA PPS
Sbjct: 1149 PTTPAATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Score = 60.5 bits (145), Expect = 4e-09
Identities = 77/313 (24%), Positives = 100/313 (31%), Gaps = 90/313 (28%)
Query: 79 LRKKPRPPEPEPAPFGPP----GAAAQPSK----PTSTVLPRSASAPGAPPLVRVPRP-- 128
L P P PA PP G A P K P + P +PG PP P P
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337
Query: 129 VEPPGDLGLPTEPQDTP-------------------------GGPASEPAQPPG-----E 158
V PP G PT P TP GGPA P P
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS 1397
Query: 159 RSADPPLPALELAQATERPSA-------------DAAPPPRAP-SEAASPCSDPPDAEPG 204
DP PA+ + P+ D PP P S +P + P P
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA 1457
Query: 205 PGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEES 264
++KG P LP P+P +EP +Q++ SP+ +P +
Sbjct: 1458 TPSSKGDPT-----LPAVTPPSP-------KEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Query: 265 GLGLGLGPGR---SPHLRR---------LSRAGPRLLSP------------DAEELPAAP 300
+ P +P RR LS+ P L+P ++ PA P
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIP 1565
Query: 301 PPSAVPLEPSEHE 313
P P PS E
Sbjct: 1566 TPKEAPATPSSKE 1578
Score = 55.5 bits (132), Expect = 1e-07
Identities = 72/281 (25%), Positives = 89/281 (31%), Gaps = 65/281 (23%)
Query: 83 PRPPEPEPAPFGPPGAAAQPS-KPTSTVLPRSASAPGAPPLVRVPRPVEPPGDL------ 135
P P P+ AP P P P +T P+ AS P P P P P
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP---PAATPPSPKGSPAATPLPKGA 1056
Query: 136 ---------------------GLPTEPQDTPGGPASEPAQP-----PGERSADPPLPALE 169
G PT P TP P PA P P +A PP P
Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116
Query: 170 LAQATER--PSADAAPPPRAPSEAASP-----CSDPPDAEPGP--GAAKGPPQQKPCMLP 220
LA + P+ AA PP A+P + P P P G A PP+ P P
Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP-TTP 1175
Query: 221 VRCVPAP-----------ATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLG 269
P+P A A P + L+ PSP+ +P G
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA-TPSPKGAPTTPAATPPSPKGGLAT 1234
Query: 270 LGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEPS 310
P +P P P + PA PPP P P+
Sbjct: 1235 PSPKGAP-------TTPAATPPSPKGGPATPPPKGAPTPPA 1268
Score = 52.0 bits (123), Expect = 1e-06
Identities = 59/240 (24%), Positives = 75/240 (31%), Gaps = 47/240 (19%)
Query: 77 VVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVP----RPVEPP 132
V L+K P P+ P P + P+ P T P S P AP V + P
Sbjct: 1441 VSLKKAPATSAPKGGP-ATPSSKGDPTLPAVT--PPSPKEPPAPKQVATSSSPKKAPATP 1497
Query: 133 GDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPAL--ELAQATERPSADAAPPPRA-PS 189
+G PT P P P PA P R P L + AT P PP PS
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 190 EAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSP 249
+P P P ++K P + P AP+ L L PSP
Sbjct: 1558 PKKTPAIPTPKEAPATPSSK-EASSPPAVTPSTYKGAPSPKEL------LIPPAVTSPSP 1610
Query: 250 RSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEP 309
+ +P P + P E+ PA P P P P
Sbjct: 1611 KEAP------------------------------TPPAVTPPSPEKGPATPAPKGTPTSP 1640
Score = 48.1 bits (113), Expect = 2e-05
Identities = 65/264 (24%), Positives = 89/264 (33%), Gaps = 48/264 (18%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGD-------- 134
P PP P+ AP +A P P LP + P +V +P P E P
Sbjct: 856 PTPPSPKGAP---TPSAVTPLSPKGVTLPPKETP--TPSVVNLPFPKEGPATPAPKQAPA 910
Query: 135 ----LGLPTEPQDTPGGPASEPAQPPGERSADPPL---PALELAQATERPSADAAPPPRA 187
P + + TP P PA P + + PP P+ + AT P PP
Sbjct: 911 LSMTSSSPKKARATPA-PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 188 PSEAASPCSDPPDAEPGPGAAKGPP-------------------QQKPCMLP--VRCVPA 226
P SP P A P P A PP P + P + PA
Sbjct: 970 PP---SPKGGP--ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 227 PATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGP 286
A P S + SP ++PL + + L G +P L+ + P
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG-APTPP 1083
Query: 287 RLLSPDAEELPAAPPPSAVPLEPS 310
P + PA P P P+ P+
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPA 1107
Score = 45.4 bits (106), Expect = 1e-04
Identities = 58/262 (22%), Positives = 87/262 (33%), Gaps = 56/262 (21%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRP-------------- 128
P P+ P+P PP +K + SA AP A P
Sbjct: 728 PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTL 787
Query: 129 ---VEPPGDLGLPTEPQ-------------DTPGGPASEPAQPPGERSADPPLPALELAQ 172
+ P LG+ PQ DTP G S P P ++ P +L
Sbjct: 788 TYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP--VEASFLPENSLSFQG 845
Query: 173 ATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRL 232
+ + P+ +P P +P A +P +A P K LP + P P+ + L
Sbjct: 846 SKDSPATTHSPTPPSPKGAPTP------------SAVTPLSPKGVTLPPKETPTPSVVNL 893
Query: 233 RAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGL----GLGPGRSPHLRRLSRAGPRL 288
+ G P+P+ +P L S + G+ SP + + P
Sbjct: 894 PFPKEG-----PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSP---KGAPTPPAA 945
Query: 289 LSPDAEELPAAPPPSAVPLEPS 310
P + PA P P P P+
Sbjct: 946 TPPSPKGGPATPSPKWAPTPPA 967
Score = 37.7 bits (86), Expect = 0.027
Identities = 45/192 (23%), Positives = 66/192 (34%), Gaps = 21/192 (10%)
Query: 79 LRKKPRPPEPEPAPFG---PPGAAAQPSKPTSTVLPRS--ASAPGAPPLVRVPRPVEPPG 133
L+ P P G P + P+K T L A AP + P++ P P
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706
Query: 134 DLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAP----- 188
T P P A ++ P A PL ++ + DA+ P+ P
Sbjct: 1707 KKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE 1766
Query: 189 SEAASPCSD-------PPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRR 241
S+A++P + P AA PP P + P P + PGL
Sbjct: 1767 SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP-LAPSPVPTLPPKQQFLPSSPGL-- 1823
Query: 242 QLSEEPSPRSSP 253
+ E PS +P
Sbjct: 1824 -VLESPSKPLAP 1834
Score = 36.2 bits (82), Expect = 0.080
Identities = 48/199 (24%), Positives = 65/199 (32%), Gaps = 40/199 (20%)
Query: 137 LPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPP--------PRAP 188
+P E +T E QP E + P AL + A +P PP P +
Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60
Query: 189 SEAASPCSDP------------PDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEE 236
+ ASP P P + G G + P LP P + L
Sbjct: 61 ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120
Query: 237 PGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEEL 296
P + L PS S+PL L L +PH + S A P L +
Sbjct: 121 PMIAPTLKGTPS-SSAPLALVAL---------------APHSVQKSSAFPPNLLTSPPSV 164
Query: 297 PAAPPPSAV----PLEPSE 311
A S + P+ PSE
Sbjct: 165 AVAESGSVITLSAPIAPSE 183
Score = 32.3 bits (72), Expect = 1.2
Identities = 37/156 (23%), Positives = 49/156 (31%), Gaps = 15/156 (9%)
Query: 95 PPGAAAQPSKPTST-VLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPA 153
P G A +K TST S G L PV+ LP P + P +
Sbjct: 655 PAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVA--- 711
Query: 154 QPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQ 213
P ++ PL L LA P PS + P PP + G +
Sbjct: 712 --PSPQNTCAPLATLVLAPEI---------PKSVPSPSLPPAGTPPGTKKVDGISHTSAL 760
Query: 214 QKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSP 249
P C + A G L++ PSP
Sbjct: 761 APVASSPKECPTEDSGASATASSKGTLTYLADSPSP 796
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 64.7 bits (156), Expect = 2e-10
Identities = 102/398 (25%), Positives = 149/398 (37%), Gaps = 69/398 (17%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASA---PGAPPLVRVPRPVEPPGDLGLPT 139
P P+P AP P + K + AS PG+P R P P P
Sbjct: 356 PSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQP-----QP 410
Query: 140 EPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSE--------- 190
+PQ P P + P PA + Q T P + PP+ P+E
Sbjct: 411 QPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEG--PPKPPTELEPEPEIEG 468
Query: 191 AASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAP---ATLRLRAEEP-GLRRQLSEE 246
+P + D + GP A P + LP P R+ AE P L+R+ S E
Sbjct: 469 LLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSME 528
Query: 247 PSP---------RSSPLLLRRLSVEESGLGLGLGPGRSPHLRRL-----SRAGPRLLSPD 292
+P + ++ RL G G G G P L + +RAGP +P
Sbjct: 529 QAPAVALPPTHKKQYQQIISRLFHRHGGPGPG---GPEPELSPITEGSEARAGPPAPAPP 585
Query: 293 AEELPAAPPPSAVPLEPSEHEW--LVRTAG----GRWTHQLHGLLLRDRGLAAKRDFM-- 344
A P AP S+ P +P E ++R AG R +LL D L + + +
Sbjct: 586 APIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQ 645
Query: 345 -------------SGFTALHWAAKSGDGEMALQLVEVARRSGAPVDVNARSHGGYTPLHL 391
G TALH A + +V+ +GA +VN+ G+TPLH
Sbjct: 646 AVKEMNDPSQPNEEGITALHNAICGAN----YSIVDFLITAGA--NVNSPDSHGWTPLHC 699
Query: 392 AALHGHEDAAVLLVVRLGAQVHVRDHS-GRRAYQYLRP 428
AA ++ + +V+ GA + S G A++ P
Sbjct: 700 AA-SCNDTVICMALVQHGAAIFATTLSDGATAFEKCDP 736
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/136 (33%), Positives = 53/136 (38%), Gaps = 30/136 (22%)
Query: 90 PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLP----TEPQDTP 145
PAP GP A PS+P PR +S+ +P EP G G P T+ DTP
Sbjct: 54 PAPPGPQ--AGPPSRP-----PRYSSSS-------IP---EPFGSRGSPRKAATDGADTP 96
Query: 146 GG-----PASEPAQP--PGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDP 198
G P P P P R + P P A +P PRA A S
Sbjct: 97 FGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRA 156
Query: 199 PDAEPGPGAAK--GPP 212
P PGPG + GPP
Sbjct: 157 PSPRPGPGPLRQQGPP 172
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 64.7 bits (156), Expect = 2e-10
Identities = 102/398 (25%), Positives = 149/398 (37%), Gaps = 69/398 (17%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASA---PGAPPLVRVPRPVEPPGDLGLPT 139
P P+P AP P + K + AS PG+P R P P P
Sbjct: 356 PSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQP-----QP 410
Query: 140 EPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSE--------- 190
+PQ P P + P PA + Q T P + PP+ P+E
Sbjct: 411 QPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEG--PPKPPTELEPEPEIEG 468
Query: 191 AASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAP---ATLRLRAEEP-GLRRQLSEE 246
+P + D + GP A P + LP P R+ AE P L+R+ S E
Sbjct: 469 LLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSME 528
Query: 247 PSP---------RSSPLLLRRLSVEESGLGLGLGPGRSPHLRRL-----SRAGPRLLSPD 292
+P + ++ RL G G G G P L + +RAGP +P
Sbjct: 529 QAPAVALPPTHKKQYQQIISRLFHRHGGPGPG---GPEPELSPITEGSEARAGPPAPAPP 585
Query: 293 AEELPAAPPPSAVPLEPSEHEW--LVRTAG----GRWTHQLHGLLLRDRGLAAKRDFM-- 344
A P AP S+ P +P E ++R AG R +LL D L + + +
Sbjct: 586 APIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQ 645
Query: 345 -------------SGFTALHWAAKSGDGEMALQLVEVARRSGAPVDVNARSHGGYTPLHL 391
G TALH A + +V+ +GA +VN+ G+TPLH
Sbjct: 646 AVKEMNDPSQPNEEGITALHNAICGAN----YSIVDFLITAGA--NVNSPDSHGWTPLHC 699
Query: 392 AALHGHEDAAVLLVVRLGAQVHVRDHS-GRRAYQYLRP 428
AA ++ + +V+ GA + S G A++ P
Sbjct: 700 AA-SCNDTVICMALVQHGAAIFATTLSDGATAFEKCDP 736
Score = 41.6 bits (96), Expect = 0.002
Identities = 45/136 (33%), Positives = 53/136 (38%), Gaps = 30/136 (22%)
Query: 90 PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLP----TEPQDTP 145
PAP GP A PS+P PR +S+ +P EP G G P T+ DTP
Sbjct: 54 PAPPGPQ--AGPPSRP-----PRYSSSS-------IP---EPFGSRGSPRKAATDGADTP 96
Query: 146 GG-----PASEPAQP--PGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDP 198
G P P P P R + P P A +P PRA A S
Sbjct: 97 FGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRA 156
Query: 199 PDAEPGPGAAK--GPP 212
P PGPG + GPP
Sbjct: 157 PSPRPGPGPLRQQGPP 172
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 63.5 bits (153), Expect = 5e-10
Identities = 105/341 (30%), Positives = 122/341 (35%), Gaps = 77/341 (22%)
Query: 50 GRAARRDRFKQFVNNVAVVK-ELDGVKFVVLRKKPR---------PPEPEPAPFGPPGAA 99
G A R +K+F +A + E G V+ R +PR PP P+PAP +
Sbjct: 599 GPAVREAAYKRFGYKLAGMDPEKPGTPIVLRRAQPRARSSNDARRPPAPQPAPRTLSHWS 658
Query: 100 AQPSKPTSTVLPRSASAPGAPP----LVRVPRPVEPPGDLGLPTEPQDTPG--------- 146
A S P P S+ P APP L +PRP P G L P P
Sbjct: 659 ALLSPPVPP-RPPSSGPPPAPPLSPALSGLPRPASPYGSLRRHPPPWAAPAHVPPAPQAS 717
Query: 147 ------GPASEPAQPPGERSADPPLP----------ALELAQATERPSADAAPPPRA--- 187
PA P PP + P P A A+ R S A P A
Sbjct: 718 WWAFVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQ 777
Query: 188 PSEAASP----CSDPPDAEPGPG-AAKGPPQQKPCMLPVRC------VPAPATLRLRAEE 236
PS +SP CS P A P P + + P Q P + P R PAP R
Sbjct: 778 PSLRSSPGLGYCS--PLAPPSPQLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGP 835
Query: 237 PGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHL-RRLSRAGPRLLSPDAEE 295
PG L P P S PL L S S L L P R PH RRLS R + P
Sbjct: 836 PG--SPLPGSPRPPSPPLGLCH-SPRRSSLNL---PSRLPHTWRRLSEPPTRAVKPQV-R 888
Query: 296 LPAAPPPSA----VPL---------EPSEHEWLVRTAGGRW 323
LP PP A PL E SE W V W
Sbjct: 889 LPFHRPPRAGAWRAPLEHRESPREPEDSETPWTVPPLAPSW 929
Score = 40.0 bits (92), Expect = 0.006
Identities = 73/275 (26%), Positives = 95/275 (34%), Gaps = 45/275 (16%)
Query: 80 RKKPRPPEPEPAPFG-PPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGD---- 134
R+ PR PE P+ PP A + T P S GA RP P +
Sbjct: 907 RESPREPEDSETPWTVPPLAPSWDVDMPPTQRPPSPWPGGAGSRRGFSRPPPVPENPFLQ 966
Query: 135 -LGLPTEPQDTPGGPASE-------------PAQPPGERSADPPLPALELAQATERPSAD 180
LG P P PA++ P Q P P E + A+
Sbjct: 967 LLGPVPSPTLQPEDPAADMTRVFLGRHHEPGPGQLTKSAGPTPEKPEEEATLGDPQLPAE 1026
Query: 181 AAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEP--- 237
PP AP + +P P D P P+QK + P P A + RA P
Sbjct: 1027 TKPPTPAPPKDVTP---PKDITPPKDVL---PEQK-TLRPSLSYPLAACDQTRATWPPWH 1079
Query: 238 --GLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGR----SPHLRRLS---RAGPRL 288
G Q + +P +P L + G PGR P +++LS R GP
Sbjct: 1080 RWGTLPQAAAPLAPIRAPEPL-----PKGGERRQAAPGRFAVVMPRVQKLSSFQRVGPAT 1134
Query: 289 LSPDAEELPAAPPPSAVPLEPSEHEWLVRTAGGRW 323
L P + + P P A L S WL A G W
Sbjct: 1135 LKPQVQPI-QDPKPRACSLRWS-CLWLRADAYGPW 1167
Score = 37.7 bits (86), Expect = 0.027
Identities = 72/283 (25%), Positives = 100/283 (35%), Gaps = 54/283 (19%)
Query: 61 FVNNVAVVKEL--DGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSK-----PTSTVLPRS 113
FV AV E+ D + F R R A FG PGA+ + S+ P ++ P
Sbjct: 721 FVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSL 780
Query: 114 ASAPGAPPLVRVPRPVEPPG-DLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQ 172
S+PG + P+ PP L L T GP P PP R +L+ +
Sbjct: 781 RSSPG----LGYCSPLAPPSPQLSLRT-------GPFQPPFLPPARRPR-----SLQESP 824
Query: 173 ATERPSADAAPP-------PRAPSEAASPCSDPPDA----------------EPGPGAAK 209
A R + PP PR PS C P + EP A K
Sbjct: 825 APRRAAGRLGPPGSPLPGSPRPPSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEPPTRAVK 884
Query: 210 GPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVE--ESGLG 267
PQ + LP P R E R+ + +P + P L V+ +
Sbjct: 885 --PQVR---LPFHRPPRAGAWRAPLEHRESPREPEDSETPWTVPPLAPSWDVDMPPTQRP 939
Query: 268 LGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEPS 310
PG + R SR P +P + L P P+ P +P+
Sbjct: 940 PSPWPGGAGSRRGFSRPPPVPENPFLQLLGPVPSPTLQPEDPA 982
Score = 35.4 bits (80), Expect = 0.14
Identities = 59/254 (23%), Positives = 90/254 (35%), Gaps = 49/254 (19%)
Query: 84 RPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQD 143
RPPEP+P PG A + + A ++ + P L + P +
Sbjct: 2436 RPPEPKPI----PGLDASTLALQQAFIHKQAVLLAREMTLQATALQQQPLSAALRSLPAE 2491
Query: 144 TPGGPASEPAQ----PPGE----RSADPPLPALELAQATERPSADAAPPPRAPSEAASPC 195
P P ++P PP + R+ PL LA+A P A P A +A+
Sbjct: 2492 KPPAPEAQPTSVGTGPPAKPVLLRATPKPLAPAPLAKAPRLPIKPVAAPVLAQDQAS--- 2548
Query: 196 SDPPDAEPGPGAAK----------GPPQQKPCMLPVRCVP----APATLRLRAEEPGLRR 241
P P P + P QQ ++ P P LR + ++R
Sbjct: 2549 --PETTSPSPELVRYSTLNSEHFPQPTQQIKNIVRQYQQPFRGGRPEALRKDGGKVFMKR 2606
Query: 242 QLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSP-DAEELPAAP 300
P P L++ + + L PG ++SR L+ P + P+
Sbjct: 2607 -----PDPHEEALMILKGQMTH----LAAAPG-----TQVSREAVALVKPVTSAPRPSMA 2652
Query: 301 PPSAVP---LEPSE 311
P SA+P LEP E
Sbjct: 2653 PTSALPSRSLEPPE 2666
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 63.5 bits (153), Expect = 5e-10
Identities = 66/245 (26%), Positives = 97/245 (39%), Gaps = 45/245 (18%)
Query: 84 RPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVP----RPVEPPGDLGLPT 139
+PP P P G A P++ T + P S+ PG L + P P + PG PT
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKP-SSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 140 EPQDTPGGPASEPAQPPGERS------------------------ADPPLPALELAQATE 175
+ TP AQ PG +S A P + + T+
Sbjct: 413 QQVGTP----KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468
Query: 176 RPS---ADAAPPPRAPSEAASPCSDPPDAEP---GPGAAKGPPQQKPCMLPVRCVP-APA 228
PS A PPP+ P A P P A+P PG+ K PPQQ P + P P
Sbjct: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG---PAKPSPQQPG 525
Query: 229 TLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGR-SPHLRRLSRAG-P 286
+ + +++PG + +++PSP V ++G G L P SP ++ G P
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Query: 287 RLLSP 291
+ + P
Sbjct: 586 KTICP 590
Score = 62.8 bits (151), Expect = 8e-10
Identities = 66/221 (29%), Positives = 94/221 (42%), Gaps = 48/221 (21%)
Query: 97 GAAAQPSKPTSTVLPRSASAPGAPPLVR------VPRPVEPPGDLGLPTEPQDTPGGPAS 150
G + +PS P+ + P PG PP + P P +PP T+P G
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 151 EPAQPPG--ERSADPPLPALELAQAT--ERPSADAAPPPRAPSEAASPCSDPPDAEPGPG 206
P QPPG + A P PA AQ T E+PS++ P P+A ++ PG
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE-QPGPKALAQP-------------PG 396
Query: 207 AAKGPPQQK-PCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESG 265
K P QQ P P + V P L A++PGL+ ++ P P +P V++
Sbjct: 397 VGKTPAQQPGPAKPPTQQVGTPKPL---AQQPGLQSP-AKAPGPTKTP-------VQQP- 444
Query: 266 LGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVP 306
GPG+ P +AGP S A++ PPS +P
Sbjct: 445 -----GPGKIP----AQQAGPGKTS--AQQTGPTKPPSQLP 474
Score = 52.8 bits (125), Expect = 8e-07
Identities = 42/160 (26%), Positives = 62/160 (38%), Gaps = 15/160 (9%)
Query: 81 KKPRP---PEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGL 137
K P P P +P P P A P K ++ + P PP ++P P +PP
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSA-----QQTGPTKPPS-QLPGPAKPPPQQPG 485
Query: 138 PTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSD 197
P +P G A P+Q PG P P A+ + + PP + P A
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPG--PAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543
Query: 198 PPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEP 237
P A+P + P Q P++ P T+ A++P
Sbjct: 544 PSPAKPSAQQSTKPVSQTGSGKPLQ----PPTVSPSAKQP 579
Score = 46.2 bits (108), Expect = 8e-05
Identities = 68/278 (24%), Positives = 102/278 (36%), Gaps = 56/278 (20%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQ----------PSKPTSTVLPRSAS-APGAPPLVRVPRPV 129
KKP P +P G P A A+ P+ P +P AP A + P+ V
Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMV 760
Query: 130 EPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPL------------PALEL-----AQ 172
+P DL + P P+S+ Q E PPL P E ++
Sbjct: 761 KPTTDLVSSSSATTKPDIPSSK-VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK 819
Query: 173 ATERPSADAA----PPPRA----------------PSEAASPCSDPPDAEPGPGAAKGPP 212
A RP++D+ P P + P +A + S PDA+P P + PP
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879
Query: 213 QQKPCMLPVRCVPAPATLRLRAEEPGLRRQL---SEEPSPRSSPLLLRR-LSVEESGLGL 268
+P + VP P + +E R L S +P+S P + ++ + G G
Sbjct: 880 GPRP--TAGQTVPTPQQ-SPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 269 GLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVP 306
+ S + + GP S + AP PS P
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPP 974
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/111 (30%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 111 PRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPA-SEPAQPPGERSADPPL-PAL 168
P S S PGAP + + P P +PP G P P PA S P + + A L P
Sbjct: 954 PHSQSGPGAP-MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012
Query: 169 ELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCML 219
E A +R + PPP S++ + ++P A K P + C L
Sbjct: 1013 EQAPTVKRTETEKKPPPIKDSKSLT--AEPQKAVLPTKLEKSPKPESTCPL 1061
Score = 42.7 bits (99), Expect = 9e-04
Identities = 57/217 (26%), Positives = 81/217 (37%), Gaps = 45/217 (20%)
Query: 120 PPLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSA 179
PPL + P P P G +P G P S +Q P + + PP + T+ P
Sbjct: 209 PPLQQQP-PKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQT 267
Query: 180 DAAPPPR--------------APSEAASPC----SDPPDAEPGPGAAKGPPQQKPCMLPV 221
D A P E+ P S PP +P PG PP Q+P
Sbjct: 268 DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK---PPAQQPG--HE 322
Query: 222 RCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGL----GLGLGPGRSPH 277
+ P PA + A+ GL + L+++P P V+ G LGP + P
Sbjct: 323 KSQPGPA--KPPAQPSGLTKPLAQQPGTVKPP-------VQPPGTTKPPAQPLGPAKPPA 373
Query: 278 LRRLS------RAGPRLLS--PDAEELPAAPPPSAVP 306
+ S + GP+ L+ P + PA P A P
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP 410
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/131 (27%), Positives = 48/131 (36%), Gaps = 20/131 (15%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAP-----PLVRVPRPVEPPGDL-- 135
P PP P P P PP P+ P T+LP+ +P PL +E L
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRS 2470
Query: 136 -GLP------TEPQDTPGGPASEPA------QPPGERSADPPLPALELAQATERPSADAA 182
GLP T P P P+S P+ +P + P P + T + D
Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH 2530
Query: 183 PPPRAPSEAAS 193
P P S +S
Sbjct: 2531 PKPTGLSLTSS 2541
Score = 37.4 bits (85), Expect = 0.036
Identities = 39/142 (27%), Positives = 54/142 (38%), Gaps = 9/142 (6%)
Query: 92 PFGPPGAAAQPSKP----TSTVLPRSAS---APGAPPLVRVPRPVEPPGDLGLPTEPQDT 144
P G P ++ P+KP S+ L SA P PP P P PP L PT P+ T
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPT 2436
Query: 145 PGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEP- 203
P + +A P A+ + T ++ P R + A P P + P
Sbjct: 2437 I-LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495
Query: 204 GPGAAKGPPQQKPCMLPVRCVP 225
G P KP + P +P
Sbjct: 2496 GLVFTHRPEPSKPPIAPKPVIP 2517
Score = 36.6 bits (83), Expect = 0.061
Identities = 42/180 (23%), Positives = 67/180 (37%), Gaps = 9/180 (5%)
Query: 79 LRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPG----D 134
++KK P + + P A P + PR + P + P+P E +
Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908
Query: 135 LGLPTE-PQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAAS 193
LG T+ P+ P P A A L +P + P AP + A
Sbjct: 909 LGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAP 968
Query: 194 PCSDPPDAEPGPGAAKGPPQQKPCMLPVR---CVPAPATLRLRAEE-PGLRRQLSEEPSP 249
S PP ++ P + P +PV+ PA L +AE+ P ++R +E+ P
Sbjct: 969 APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP 1028
Score = 30.0 bits (66), Expect = 5.7
Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 7/84 (8%)
Query: 148 PASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGA 207
PAS+ S+ P P ++ SA PPP P P PP P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP-----PPPPPPPPPPPPPP 2426
Query: 208 AKGPPQQKPCMLPVR--CVPAPAT 229
P KP +LP + V +P T
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVT 2450
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 63.5 bits (153), Expect = 5e-10
Identities = 66/245 (26%), Positives = 97/245 (39%), Gaps = 45/245 (18%)
Query: 84 RPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVP----RPVEPPGDLGLPT 139
+PP P P G A P++ T + P S+ PG L + P P + PG PT
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKP-SSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 140 EPQDTPGGPASEPAQPPGERS------------------------ADPPLPALELAQATE 175
+ TP AQ PG +S A P + + T+
Sbjct: 413 QQVGTP----KPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468
Query: 176 RPS---ADAAPPPRAPSEAASPCSDPPDAEP---GPGAAKGPPQQKPCMLPVRCVP-APA 228
PS A PPP+ P A P P A+P PG+ K PPQQ P + P P
Sbjct: 469 PPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG---PAKPSPQQPG 525
Query: 229 TLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGR-SPHLRRLSRAG-P 286
+ + +++PG + +++PSP V ++G G L P SP ++ G P
Sbjct: 526 STKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585
Query: 287 RLLSP 291
+ + P
Sbjct: 586 KTICP 590
Score = 62.8 bits (151), Expect = 8e-10
Identities = 66/221 (29%), Positives = 94/221 (42%), Gaps = 48/221 (21%)
Query: 97 GAAAQPSKPTSTVLPRSASAPGAPPLVR------VPRPVEPPGDLGLPTEPQDTPGGPAS 150
G + +PS P+ + P PG PP + P P +PP T+P G
Sbjct: 291 GESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350
Query: 151 EPAQPPG--ERSADPPLPALELAQAT--ERPSADAAPPPRAPSEAASPCSDPPDAEPGPG 206
P QPPG + A P PA AQ T E+PS++ P P+A ++ PG
Sbjct: 351 PPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSE-QPGPKALAQP-------------PG 396
Query: 207 AAKGPPQQK-PCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESG 265
K P QQ P P + V P L A++PGL+ ++ P P +P V++
Sbjct: 397 VGKTPAQQPGPAKPPTQQVGTPKPL---AQQPGLQSP-AKAPGPTKTP-------VQQP- 444
Query: 266 LGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVP 306
GPG+ P +AGP S A++ PPS +P
Sbjct: 445 -----GPGKIP----AQQAGPGKTS--AQQTGPTKPPSQLP 474
Score = 52.8 bits (125), Expect = 8e-07
Identities = 42/160 (26%), Positives = 62/160 (38%), Gaps = 15/160 (9%)
Query: 81 KKPRP---PEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGL 137
K P P P +P P P A P K ++ + P PP ++P P +PP
Sbjct: 432 KAPGPTKTPVQQPGPGKIPAQQAGPGKTSA-----QQTGPTKPPS-QLPGPAKPPPQQPG 485
Query: 138 PTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSD 197
P +P G A P+Q PG P P A+ + + PP + P A
Sbjct: 486 PAKPPPQQPGSAKPPSQQPGSTKPPPQQPG--PAKPSPQQPGSTKPPSQQPGSAKPSAQQ 543
Query: 198 PPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEP 237
P A+P + P Q P++ P T+ A++P
Sbjct: 544 PSPAKPSAQQSTKPVSQTGSGKPLQ----PPTVSPSAKQP 579
Score = 46.2 bits (108), Expect = 8e-05
Identities = 68/278 (24%), Positives = 102/278 (36%), Gaps = 56/278 (20%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQ----------PSKPTSTVLPRSAS-APGAPPLVRVPRPV 129
KKP P +P G P A A+ P+ P +P AP A + P+ V
Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMV 760
Query: 130 EPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPL------------PALEL-----AQ 172
+P DL + P P+S+ Q E PPL P E ++
Sbjct: 761 KPTTDLVSSSSATTKPDIPSSK-VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSK 819
Query: 173 ATERPSADAA----PPPRA----------------PSEAASPCSDPPDAEPGPGAAKGPP 212
A RP++D+ P P + P +A + S PDA+P P + PP
Sbjct: 820 AIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879
Query: 213 QQKPCMLPVRCVPAPATLRLRAEEPGLRRQL---SEEPSPRSSPLLLRR-LSVEESGLGL 268
+P + VP P + +E R L S +P+S P + ++ + G G
Sbjct: 880 GPRP--TAGQTVPTPQQ-SPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA 936
Query: 269 GLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVP 306
+ S + + GP S + AP PS P
Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPP 974
Score = 44.3 bits (103), Expect = 3e-04
Identities = 34/111 (30%), Positives = 47/111 (42%), Gaps = 5/111 (4%)
Query: 111 PRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPA-SEPAQPPGERSADPPL-PAL 168
P S S PGAP + + P P +PP G P P PA S P + + A L P
Sbjct: 954 PHSQSGPGAP-MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012
Query: 169 ELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCML 219
E A +R + PPP S++ + ++P A K P + C L
Sbjct: 1013 EQAPTVKRTETEKKPPPIKDSKSLT--AEPQKAVLPTKLEKSPKPESTCPL 1061
Score = 42.7 bits (99), Expect = 9e-04
Identities = 57/217 (26%), Positives = 81/217 (37%), Gaps = 45/217 (20%)
Query: 120 PPLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSA 179
PPL + P P P G +P G P S +Q P + + PP + T+ P
Sbjct: 209 PPLQQQP-PKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQT 267
Query: 180 DAAPPPR--------------APSEAASPC----SDPPDAEPGPGAAKGPPQQKPCMLPV 221
D A P E+ P S PP +P PG PP Q+P
Sbjct: 268 DHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK---PPAQQPG--HE 322
Query: 222 RCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGL----GLGLGPGRSPH 277
+ P PA + A+ GL + L+++P P V+ G LGP + P
Sbjct: 323 KSQPGPA--KPPAQPSGLTKPLAQQPGTVKPP-------VQPPGTTKPPAQPLGPAKPPA 373
Query: 278 LRRLS------RAGPRLLS--PDAEELPAAPPPSAVP 306
+ S + GP+ L+ P + PA P A P
Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKP 410
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/131 (27%), Positives = 48/131 (36%), Gaps = 20/131 (15%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAP-----PLVRVPRPVEPPGDL-- 135
P PP P P P PP P+ P T+LP+ +P PL +E L
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRS 2470
Query: 136 -GLP------TEPQDTPGGPASEPA------QPPGERSADPPLPALELAQATERPSADAA 182
GLP T P P P+S P+ +P + P P + T + D
Sbjct: 2471 NGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH 2530
Query: 183 PPPRAPSEAAS 193
P P S +S
Sbjct: 2531 PKPTGLSLTSS 2541
Score = 37.4 bits (85), Expect = 0.036
Identities = 39/142 (27%), Positives = 54/142 (38%), Gaps = 9/142 (6%)
Query: 92 PFGPPGAAAQPSKP----TSTVLPRSAS---APGAPPLVRVPRPVEPPGDLGLPTEPQDT 144
P G P ++ P+KP S+ L SA P PP P P PP L PT P+ T
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPT 2436
Query: 145 PGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEP- 203
P + +A P A+ + T ++ P R + A P P + P
Sbjct: 2437 I-LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495
Query: 204 GPGAAKGPPQQKPCMLPVRCVP 225
G P KP + P +P
Sbjct: 2496 GLVFTHRPEPSKPPIAPKPVIP 2517
Score = 36.6 bits (83), Expect = 0.061
Identities = 42/180 (23%), Positives = 67/180 (37%), Gaps = 9/180 (5%)
Query: 79 LRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPG----D 134
++KK P + + P A P + PR + P + P+P E +
Sbjct: 849 VQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908
Query: 135 LGLPTE-PQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAAS 193
LG T+ P+ P P A A L +P + P AP + A
Sbjct: 909 LGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAP 968
Query: 194 PCSDPPDAEPGPGAAKGPPQQKPCMLPVR---CVPAPATLRLRAEE-PGLRRQLSEEPSP 249
S PP ++ P + P +PV+ PA L +AE+ P ++R +E+ P
Sbjct: 969 APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPP 1028
Score = 30.0 bits (66), Expect = 5.7
Identities = 25/84 (29%), Positives = 32/84 (38%), Gaps = 7/84 (8%)
Query: 148 PASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGA 207
PAS+ S+ P P ++ SA PPP P P PP P P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP-----PPPPPPPPPPPPPP 2426
Query: 208 AKGPPQQKPCMLPVR--CVPAPAT 229
P KP +LP + V +P T
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVT 2450
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 63.2 bits (152), Expect = 6e-10
Identities = 71/240 (29%), Positives = 92/240 (38%), Gaps = 21/240 (8%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQ 142
P P P P+P PP PS P +T ++ ++ G+P L + P L T P
Sbjct: 298 PSPSAP-PSPSAPPSLQTLPSPP-ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 143 DTPGGPASEPAQPPGERSADPPL-------PALELAQATERPSADAAPPPRAPSEA--AS 193
P A P Q P A PPL P A A A +PPP P +A +
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415
Query: 194 PCSDP--PDAEP---GPGAAKGPPQQKPCMLPVRCVPAP-ATLRLRAEEPGLRRQLSEEP 247
P S P P A P P + PP Q P P +P AT +A P L
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475
Query: 248 SPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPL 307
P +P L ++ PG++P S + +SP A P APP A PL
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAP----FSPSASLPMSPLATPPPQAPPVLAAPL 531
Score = 60.8 bits (146), Expect = 3e-09
Identities = 68/206 (33%), Positives = 82/206 (39%), Gaps = 31/206 (15%)
Query: 77 VVLRKKPRPPEPEP---APFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPG 133
V L + P P P P APF PP A+ P P++T ++ + APPL P P P
Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP- 450
Query: 134 DLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAAS 193
P P TP A P P + A PP P A AT P A P P A +
Sbjct: 451 ----PMSPSATPPPQAPPPLAAPPLQLAKPP-PQAPPALAT--PPLQALPSPPASFPGQA 503
Query: 194 PCSDPPDAEPGPGAAKGPPQQKPCM-LPVRCVP--APATLRLRAEEPGLRRQLSEEPSPR 250
P S P + P A PPQ P + P+ VP PA+ L+A PR
Sbjct: 504 PFS-PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA--------------PR 548
Query: 251 SSPLLLRRLSVEESGLGLGLGPGRSP 276
P SV L L L PG P
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPP 574
Score = 58.5 bits (140), Expect = 2e-08
Identities = 78/277 (28%), Positives = 101/277 (36%), Gaps = 57/277 (20%)
Query: 79 LRKKPRPPEPEPAP----FGPPGAAAQ-------PSKPTSTVLPRSASAPGAPPLVRVPR 127
L+ P PP P+ G P A P P +T P++ A PPL P
Sbjct: 312 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 371
Query: 128 PVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRA 187
P P L T P A Q P PP+ A A+ S A PP +A
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 431
Query: 188 PSEAA----------------SPCSDPPDAEPGPGA------AKGPPQQKPCML--PVRC 223
P A SP + PP P P A AK PPQ P + P++
Sbjct: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491
Query: 224 VPA-PATLRLRAE-EPGLRRQLS--EEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLR 279
+P+ PA+ +A P +S P P++ P+L L L + P SP L+
Sbjct: 492 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL------LQVPPSPPASPTLQ 545
Query: 280 RLSR----------AGPRLLSPDAEELPAAPPPSAVP 306
R +GPRL A P PPPS P
Sbjct: 546 APRRPPTPGPDTSVSGPRLTLALAPGPP--PPPSRSP 580
Score = 56.2 bits (134), Expect = 7e-08
Identities = 70/244 (28%), Positives = 85/244 (34%), Gaps = 39/244 (15%)
Query: 85 PPEPEPAPFGPPGAAAQPSKPTSTVL----------PRSASAPGAPPL----VRVPRPVE 130
P P+ G P A A PS+P L PR +AP PL + P P
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302
Query: 131 PPGDLGLPT-----EPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPP 185
PP P+ P TP A+ P ++ LP+ L S A PPP
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL-------SPLATPPP 355
Query: 186 RAPSEAASP---CSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQ 242
+AP A P P A P P Q P L V + AP + P ++
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS---PPPSPPVQAP 412
Query: 243 LSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPP 302
S SP SP S L SP A P +SP A P APPP
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP------PASPP-MSPSATPPPQAPPP 465
Query: 303 SAVP 306
A P
Sbjct: 466 LAAP 469
Score = 48.5 bits (114), Expect = 2e-05
Identities = 58/224 (25%), Positives = 78/224 (34%), Gaps = 16/224 (7%)
Query: 90 PAPFGPPGAAAQPSKPTSTVLPRSASAPG----APPLVRVPRPVEPPGDLGLPTEPQDTP 145
PA PG + P + + T P G A V + E P L +
Sbjct: 96 PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 155
Query: 146 GGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGP 205
GP P P + E+ PSA PP P ++ S S+ EP P
Sbjct: 156 SGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 213
Query: 206 GAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLS-VEES 264
A + P + PA+ L + L PS R +P S +
Sbjct: 214 AARRRPSAGGG-------LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266
Query: 265 GLGLGLGPGRSPHLRRLSRA-GPRLLSPDAEELPAAPP-PSAVP 306
GL P +P + + A GP SP A P+APP PSA P
Sbjct: 267 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310
Score = 47.8 bits (112), Expect = 3e-05
Identities = 75/276 (27%), Positives = 93/276 (33%), Gaps = 39/276 (14%)
Query: 65 VAVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTV--LPRSASAPGAPPL 122
VA K + K L R P P P A A+ S+ T LPR A + P
Sbjct: 133 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192
Query: 123 VRVPRPVEPPGDLGLPTEP------QDTPGGPASEPAQPPGERSADP---PLPALELAQA 173
PR TEP + + GG PA SA P P + A+
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252
Query: 174 TERPSA----------------DAAPPPRAPSEAASPCSDPPDAEPGPGA---AKGPPQQ 214
T R A PP + + A P S P A P P A PP
Sbjct: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312
Query: 215 KPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEES----GLGLGL 270
+ P P+ AT L + P L+ S PSP SPL + L
Sbjct: 313 QTLPSPPATPPSQATTSLGS--PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370
Query: 271 GPGRSPHLRRL---SRAGPRLLSPDAEELPAAPPPS 303
P SP L L S P L+ + P +PPPS
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 406
Score = 47.4 bits (111), Expect = 3e-05
Identities = 72/258 (27%), Positives = 93/258 (36%), Gaps = 46/258 (17%)
Query: 87 EPEPAPFGPPGAAAQPSKPTSTVLPRSA--------SAPGAPPLVRVPRPVEPPGDLGLP 138
EP PA P A +P S L SA S P A R P P GL
Sbjct: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 269
Query: 139 T--EPQDTPGGPASEPAQPPGERSADP---PLPALELAQATERPSADAAP-PPRAPSEAA 192
PQ TP P + A G S+ P P P+ + + PS P PP P A
Sbjct: 270 ALRPPQVTP--PRKDAAPALGPLSSSPLATPSPSAPPSPSAP-PSLQTLPSPPATPPSQA 326
Query: 193 SPCSDPPDAE------PGP---GAAKGPPQQKPCML--PVRCVPAP---------ATLRL 232
+ P + P P A PPQ P + P++ P+P AT
Sbjct: 327 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386
Query: 233 RAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPD 292
+A L SP SP + S S P SP S+A P L +P
Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS-------PPVSPSATPPSQAPPSLAAPP 439
Query: 293 AEELPAAPPPSAVPLEPS 310
+ P+ PP++ P+ PS
Sbjct: 440 LQVPPS--PPASPPMSPS 455
Score = 42.4 bits (98), Expect = 0.001
Identities = 69/231 (29%), Positives = 76/231 (32%), Gaps = 60/231 (25%)
Query: 83 PRPPEPEPAPFGPPGAAAQ-----PSKPTSTVL--PRSASAPGAPPLVRVPR-------- 127
P P P P PP AA PS P S L PR PG V PR
Sbjct: 512 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571
Query: 128 PVEPPGDLGLPTEPQDTPGGP---------ASEPAQ-------PPGERSADPPLPALELA 171
P PP P T GP S P + P G +A PP P ELA
Sbjct: 572 PPPPPS-----RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP-PDAELA 625
Query: 172 QATERP-SADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
S APP +P PP GPG+A G P PAP L
Sbjct: 626 ACHPAAWSRGPAPPLAFRGAPGAPLPWPP--ATGPGSADGLCTIYETEGPESATPAPGAL 683
Query: 231 RLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRL 281
+PG PSP +S +G G G RSP RL
Sbjct: 684 -----DPG--------PSPGTSG------GKAAAGAGAG-ASSRSPKQARL 714
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 62.8 bits (151), Expect = 8e-10
Identities = 47/154 (30%), Positives = 61/154 (39%), Gaps = 19/154 (12%)
Query: 84 RPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQD 143
R P P AP P AA P++ A PGAPP R P P G P +
Sbjct: 507 RLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQ 566
Query: 144 T----PGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPP 199
T P P + A P G++ PP ++P A P +A P + PP
Sbjct: 567 TSVSGPAPPKASGAPPGGQQRQGPP----------QKPPGPAGPTRQASQAGPVPRTGPP 616
Query: 200 DAE----PGPGAAKGPPQQKPCMLPVRCVPAPAT 229
+ GPG A G P+ + P + VP PAT
Sbjct: 617 TTQQPRPSGPGPA-GRPKPQLAQKPSQDVPPPAT 649
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/247 (26%), Positives = 86/247 (34%), Gaps = 61/247 (24%)
Query: 86 PEPEPAPFG------PPGAAAQPSKPTSTVLPRSASAPG--APPLVRVPRPV--EPPGDL 135
P P P G P G AQ P P+ P PPL + P P + L
Sbjct: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGL 496
Query: 136 GLPTE---PQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAA 192
G P PQ P P S P QP + A PP Q R S A P AP A
Sbjct: 497 GPPAGSPLPQRLPS-PTSAPQQPASQ--AAPP------TQGQGRQSRPVAGGPGAPPAAR 547
Query: 193 SPCSDPPDAEPG---------------PGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEP 237
P S P + G P A+ PP + P + P PA +A +
Sbjct: 548 PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQA 607
Query: 238 GLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELP 297
G P PR+ P ++ GPG + R P+L ++++P
Sbjct: 608 G--------PVPRTGPPTTQQPRPS--------GPGPA------GRPKPQLAQKPSQDVP 645
Query: 298 AAPPPSA 304
PP +A
Sbjct: 646 --PPATA 650
Score = 41.6 bits (96), Expect = 0.002
Identities = 36/113 (31%), Positives = 44/113 (38%), Gaps = 9/113 (7%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLP-RSASAPG-----APPLVRVPRPVEPPGDLG 136
P PP+ AP G P KP P R AS G PP + PRP PG G
Sbjct: 572 PAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRP-SGPGPAG 630
Query: 137 LPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPS 189
P +PQ P+ + P + PP P L +Q+ P P PS
Sbjct: 631 RP-KPQ-LAQKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLPEPAPPRPS 681
Score = 31.6 bits (70), Expect = 2.0
Identities = 38/157 (24%), Positives = 53/157 (33%), Gaps = 13/157 (8%)
Query: 157 GERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKP 216
G P AL L + T + A R P + P P GP + PP Q
Sbjct: 431 GSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQ 490
Query: 217 CMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSP 276
L PA + L R P ++P+ +++P + G GPG P
Sbjct: 491 QHLSGLGPPAGSPLPQRLPSP---TSAPQQPASQAAPPTQGQGRQSRPVAG---GPGAPP 544
Query: 277 HLRRLSRAGPRLLS--PDAEEL-----PAAPPPSAVP 306
R + P+ + P A PA P S P
Sbjct: 545 AARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAP 581
Score = 29.6 bits (65), Expect = 7.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 3/46 (6%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVP 126
++P+PP P P P A P T+T S AP A P P
Sbjct: 26 QRPQPPPPPPGAHSP---GATPGPGTATAERSSGVAPAASPAAPSP 68
Score = 29.3 bits (64), Expect = 9.8
Identities = 24/82 (29%), Positives = 32/82 (39%), Gaps = 15/82 (18%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTE 140
++PRP P PA P A KP+ V P + +A G PP ++ + LP
Sbjct: 619 QQPRPSGPGPAGRPKPQLA---QKPSQDVPPPATAAAGGPPHPQLNKSQSLTNAFNLP-- 673
Query: 141 PQDTPGGPASEPAQPPGERSAD 162
EPA P S D
Sbjct: 674 ----------EPAPPRPSLSQD 685
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 62.8 bits (151), Expect = 8e-10
Identities = 47/154 (30%), Positives = 61/154 (39%), Gaps = 19/154 (12%)
Query: 84 RPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQD 143
R P P AP P AA P++ A PGAPP R P P G P +
Sbjct: 507 RLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQ 566
Query: 144 T----PGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPP 199
T P P + A P G++ PP ++P A P +A P + PP
Sbjct: 567 TSVSGPAPPKASGAPPGGQQRQGPP----------QKPPGPAGPTRQASQAGPVPRTGPP 616
Query: 200 DAE----PGPGAAKGPPQQKPCMLPVRCVPAPAT 229
+ GPG A G P+ + P + VP PAT
Sbjct: 617 TTQQPRPSGPGPA-GRPKPQLAQKPSQDVPPPAT 649
Score = 47.0 bits (110), Expect = 5e-05
Identities = 44/134 (32%), Positives = 52/134 (38%), Gaps = 26/134 (19%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPP--LVRVPRPVEPPGDLGLP 138
+ P P P+ GPP A Q TS P A GAPP R P +PPG G P
Sbjct: 547 RPPASPSPQRQA-GPPQATRQ----TSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG-P 600
Query: 139 TE------PQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPP-------P 185
T P G P ++ +P G A P P Q ++PS D PP P
Sbjct: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP-----QLAQKPSQDVPPPATAAAGGP 655
Query: 186 RAPSEAASPCSDPP 199
P ASP P
Sbjct: 656 PHPQLKASPAQAQP 669
Score = 45.8 bits (107), Expect = 1e-04
Identities = 66/254 (25%), Positives = 86/254 (33%), Gaps = 52/254 (20%)
Query: 86 PEPEPAPFG------PPGAAAQPSKPTSTVLPRSASAPG--APPLVRVPRPV--EPPGDL 135
P P P G P G AQ P P+ P PPL + P P + L
Sbjct: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGL 496
Query: 136 GLPTE---PQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAA 192
G P PQ P P S P QP + A PP Q R S A P AP A
Sbjct: 497 GPPAGSPLPQRLPS-PTSAPQQPASQ--AAPP------TQGQGRQSRPVAGGPGAPPAAR 547
Query: 193 SPCSDPPDAEPG---------------PGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEP 237
P S P + G P A+ PP + P + P PA +A +
Sbjct: 548 PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQA 607
Query: 238 GLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELP 297
G P PR+ P + G GP P +L++ + + P A
Sbjct: 608 G--------PVPRTGP------PTTQQPRPSGPGPAGRPK-PQLAQKPSQDVPPPATAAA 652
Query: 298 AAPPPSAVPLEPSE 311
PP + P++
Sbjct: 653 GGPPHPQLKASPAQ 666
Score = 31.6 bits (70), Expect = 2.0
Identities = 38/157 (24%), Positives = 53/157 (33%), Gaps = 13/157 (8%)
Query: 157 GERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKP 216
G P AL L + T + A R P + P P GP + PP Q
Sbjct: 431 GSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQ 490
Query: 217 CMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSP 276
L PA + L R P ++P+ +++P + G GPG P
Sbjct: 491 QHLSGLGPPAGSPLPQRLPSP---TSAPQQPASQAAPPTQGQGRQSRPVAG---GPGAPP 544
Query: 277 HLRRLSRAGPRLLS--PDAEEL-----PAAPPPSAVP 306
R + P+ + P A PA P S P
Sbjct: 545 AARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAP 581
Score = 29.6 bits (65), Expect = 7.5
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 3/46 (6%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVP 126
++P+PP P P P A P T+T S AP A P P
Sbjct: 26 QRPQPPPPPPGAHSP---GATPGPGTATAERSSGVAPAASPAAPSP 68
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 62.4 bits (150), Expect = 1e-09
Identities = 74/267 (27%), Positives = 90/267 (33%), Gaps = 49/267 (18%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVL---------------------PRSAS-APGAP 120
P P P AP PG ++ PS P L P+S S P P
Sbjct: 758 PAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEP 817
Query: 121 PLVRVPRPVEPP---------GDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELA 171
PL P P PP LG+P P P A P QPP + PP L A
Sbjct: 818 PLHPCPPPQAPPTLPGIFVIQNQLGVP-PPASNPAPTAPGPPQPPLRPQSQPPEGPLPPA 876
Query: 172 QATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLR 231
PP + S A + S+ P P + Q P P + P TL
Sbjct: 877 PHL---------PPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLH 927
Query: 232 LRAE------EPGLRRQLSEEPSPR--SSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSR 283
L E P Q+ P P LL R SG+ L G +P + S
Sbjct: 928 LVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTST 987
Query: 284 AGPRLLSPDAEELPAAPPPSAVPLEPS 310
+ L SP A L + PS P PS
Sbjct: 988 SLGPLTSPAASVLVSGQAPSGTPTAPS 1014
Score = 59.7 bits (143), Expect = 7e-09
Identities = 61/238 (25%), Positives = 83/238 (34%), Gaps = 48/238 (20%)
Query: 85 PPEPEPAPFGP--PGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQ 142
PP +PAP P GA P P S ++P P + P++ PG P+ P
Sbjct: 728 PPAQDPAPATPVAKGAGLGPQAPD------SQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
Query: 143 DTPGG-----PASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSE------- 190
P G P+ P +PP PP +++ P PPP+AP
Sbjct: 782 QAPLGDSPHLPSPHPTRPPSR----PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVI 837
Query: 191 -----AASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSE 245
P S+P PGP PQ +P P+ P + S
Sbjct: 838 QNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSR 897
Query: 246 EPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRL-LSPDAEELPAAPPP 302
P+P S L+ P + PH + P L L P+ PAAPPP
Sbjct: 898 LPAPTPSDFQLQ------------FPPSQGPH--KSPTPPPTLHLVPE----PAAPPP 937
Score = 54.7 bits (130), Expect = 2e-07
Identities = 82/327 (25%), Positives = 113/327 (34%), Gaps = 55/327 (16%)
Query: 2 ALAAAAAAAAAGVSQAAVLGFLQEHGGKVRNSELLSRFKPLLDAGDPRGRAARRDRFKQF 61
A A+++ ++++ S AA E G + SR +P + + R R + + KQ
Sbjct: 1262 ARASSSLSSSSSSSSAASSLDADEDG------PMPSRNRPPIKTYEARSRIGLKLKIKQE 1315
Query: 62 VNNVAVVKE--LDGVK--------FVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLP 111
VV LD V V PRPP P P P G P +
Sbjct: 1316 AGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPP-PTGQMNGTVDHPPPAAPERK 1374
Query: 112 RSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPAL--E 169
+AP P R+P ++G P P+ TP G A + P D L E
Sbjct: 1375 PLGTAPHCP---RLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRE 1431
Query: 170 LAQATER--PSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAP 227
LA + PPP + AA DP PG AK
Sbjct: 1432 LAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAK------------------ 1473
Query: 228 ATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPR 287
R ++E P + + SP+ L S +S L L PGR+P P
Sbjct: 1474 ---RRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTP--------APS 1522
Query: 288 LLSPDAEELPAAPPPSAVP--LEPSEH 312
+ PA+PPP P PS H
Sbjct: 1523 YPHAASAGTPASPPPLHRPEAYPPSSH 1549
Score = 52.8 bits (125), Expect = 8e-07
Identities = 73/253 (28%), Positives = 98/253 (38%), Gaps = 35/253 (13%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAP-----GAPPLVRVPRPVEPPGDL 135
++P+ +P AP P AAA P T P AS+P G PP P + L
Sbjct: 640 QQPQAQQPPQAP--TPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSA-TPTAILTQDSL 696
Query: 136 G--LPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAAS 193
LP E P P P PA + A AT + A P+AP AS
Sbjct: 697 QMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATP-VAKGAGLGPQAPDSQAS 755
Query: 194 PCSDP--PDAEP--GPGAAKGP--PQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEP 247
P P P A P GPG + P P Q P + +P+P R + P + +S P
Sbjct: 756 PAPAPQIPAAAPLKGPGPSSSPSLPHQAP-LGDSPHLPSPHPTRPPSRPPSRPQSVSRPP 814
Query: 248 S--------PRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAA 299
S P +P L + V ++ LG+ P +P + GP P P +
Sbjct: 815 SEPPLHPCPPPQAPPTLPGIFVIQNQLGVP-PPASNP---APTAPGP----PQPPLRPQS 866
Query: 300 PPPSAVPLEPSEH 312
PP PL P+ H
Sbjct: 867 QPPEG-PLPPAPH 878
Score = 51.6 bits (122), Expect = 2e-06
Identities = 63/234 (26%), Positives = 92/234 (39%), Gaps = 29/234 (12%)
Query: 89 EPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVE-PPGDLGLPTEPQD---- 143
+PA F P + A S PT +S AP P V + V PP + + P
Sbjct: 551 QPALFQMPVSLAAGSLPT-----QSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQP 605
Query: 144 -TPGGPASEPAQPPGERSAD--PPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPD 200
TP E A + A PP + L ++P A P P AA P + P
Sbjct: 606 ATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP- 664
Query: 201 AEPGPGAAKGPPQ----QKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLL 256
+P PG A P + Q P P A L + + L ++ S++P P L
Sbjct: 665 -QPSPGLASSPEKIVLGQPPSATPT------AILTQDSLQMFLPQERSQQPLSAEGPHLS 717
Query: 257 RRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPP--PSAVPLE 308
SV S P + + + + GP+ +PD++ PA P P+A PL+
Sbjct: 718 VPASVIVSAPPPAQDPAPATPVAKGAGLGPQ--APDSQASPAPAPQIPAAAPLK 769
Score = 37.7 bits (86), Expect = 0.027
Identities = 53/202 (26%), Positives = 74/202 (36%), Gaps = 56/202 (27%)
Query: 84 RPPEPEPAPFG---PPGAAAQPSK---PTSTVLPRSASAPGAPP----LVRVPRPVEP-- 131
R P P P+ F PP S PT ++P A+ P PP +V P P P
Sbjct: 897 RLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQP 956
Query: 132 ----------PGDL-------GLPTEPQ-DTPGGPASEPA-------QPPGERSADPPLP 166
P + G P PQ T GP + PA Q P S P P
Sbjct: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAP---SGTPTAP 1013
Query: 167 ALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPA 226
+ A A P A PP P+E + S+ P A+ GP +
Sbjct: 1014 SHAPAPA---PMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGK------------- 1057
Query: 227 PATLRLRAEEPGLRRQLSEEPS 248
P+ L+ ++ GL++ + +PS
Sbjct: 1058 PSGLQYESKLSGLKKPPTLQPS 1079
Score = 34.7 bits (78), Expect = 0.23
Identities = 43/148 (29%), Positives = 54/148 (36%), Gaps = 25/148 (16%)
Query: 85 PPEPEPAPFG----PPGAAAQPSK--------PTSTVLPRSAS-APGAPPLVRVPRPVEP 131
PP P P F P A QP P+ +L A AP AP P+
Sbjct: 935 PPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS 994
Query: 132 PGDLGLPT--EPQDTPGGPASEPAQPPGERSADPP-LPALELAQATERPSAD----AAPP 184
P L + P TP P+ PA P + PP LPA A A+ P+ + A+
Sbjct: 995 PAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSG 1054
Query: 185 PRAPS-----EAASPCSDPPDAEPGPGA 207
P PS S PP +P A
Sbjct: 1055 PGKPSGLQYESKLSGLKKPPTLQPSKEA 1082
Score = 32.3 bits (72), Expect = 1.2
Identities = 63/266 (23%), Positives = 98/266 (36%), Gaps = 53/266 (19%)
Query: 93 FGPPGAAAQPSKPTS----TVLPRSASAPGAPP----LVRVPRPVEP-PGDLGLPTEPQD 143
FG GAA+ P+ S V P S+P P L R P P++P P + P Q
Sbjct: 307 FGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQL 366
Query: 144 TP-------------GGPASEPAQPPGERS---------------ADPPLPALELAQATE 175
TP G P + P QP ++ + P PAL+ A +
Sbjct: 367 TPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQ-ANVFK 425
Query: 176 RPSA--DAAPPPRAPSEAASPCS----DPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPAT 229
+P A A PP+ P + P S + + P P Q + + V P
Sbjct: 426 QPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ- 484
Query: 230 LRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLG--LGLGPGRSPH-----LRRLS 282
+L A + Q+ +P + L+ + L L LGP +PH LS
Sbjct: 485 -QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILS 543
Query: 283 RAGPRLLSPDAEELPAAPPPSAVPLE 308
A ++ P ++P + ++P +
Sbjct: 544 AAPIQVGQPALFQMPVSLAAGSLPTQ 569
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 62.0 bits (149), Expect = 1e-09
Identities = 64/244 (26%), Positives = 79/244 (32%), Gaps = 32/244 (13%)
Query: 81 KKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTE 140
K +PP P P GPPG P P P PPL P + PP GLP
Sbjct: 213 KMEKPPAPPSLPAGPPGVKRPPP-------PLMNGLPPRPPL---PESLPPPPPGGLPLP 262
Query: 141 PQ----DTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCS 196
P P GP P PP PP P + + P A PP +P
Sbjct: 263 PMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGV 322
Query: 197 DPPDA---EPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSP 253
PP + P PG P P P V PA + PG+ S P++
Sbjct: 323 HPPTSGVHPPAPGVHPPAPGVHP---PAPGVHPPAP-GVHPPAPGVHPPPSAGVHPQAPG 378
Query: 254 LLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAP-----PPSAVPLE 308
+ +V PG P + P + P+AP PP P
Sbjct: 379 VHPAAPAVHPQ------APGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSN 432
Query: 309 PSEH 312
P H
Sbjct: 433 PGVH 436
Score = 48.9 bits (115), Expect = 1e-05
Identities = 56/226 (24%), Positives = 68/226 (30%), Gaps = 42/226 (18%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRP--------VEPPGD 134
PRPP PE P PPG P P + P S P PP + P P V PP
Sbjct: 243 PRPPLPESLPPPPPGGLPLPPMPPTGPAP---SGPPGPPQLPPPAPGVHPPAPVVHPPAS 299
Query: 135 LGLPTEPQDTPGGPASEPAQP------------------------PGERSADPPLPALEL 170
P P P P P P P PP P +
Sbjct: 300 GVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHP 359
Query: 171 AQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
P A P+AP + + P A A G Q P + P P+
Sbjct: 360 PAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAP 419
Query: 231 RLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSP 276
+ + PG+ P P +LR E GPG P
Sbjct: 420 GVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSE-------GPGNIP 458
Score = 38.9 bits (89), Expect = 0.012
Identities = 39/130 (30%), Positives = 43/130 (33%), Gaps = 14/130 (10%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQ 142
P P PAP P A P++ V P+ APG P P P P P
Sbjct: 346 PAPGVHPPAPGVHPPAPGVHPPPSAGVHPQ---APGVHPAAPAVHPQAPGVH---PPAPG 399
Query: 143 DTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAE 202
P P P QPPG P P + PS PP P PP
Sbjct: 400 MHPQAPGVHP-QPPG---VHPSAPGVHPQPPGVHPSNPGVHPP----TPMPPMLRPPLPS 451
Query: 203 PGPGAAKGPP 212
GPG PP
Sbjct: 452 EGPGNIPPPP 461
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 61.6 bits (148), Expect = 2e-09
Identities = 50/144 (34%), Positives = 54/144 (37%), Gaps = 11/144 (7%)
Query: 83 PRPPEPE---PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPP-GDLGLP 138
P PP P P P PGA P P LP A P PPL RV P PP G+P
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPP----LP-GAGIPPPPPLPRVGIPPPPPLPGAGIP 1163
Query: 139 TEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDP 198
P G P P PPLP + + P A PPP P P P
Sbjct: 1164 PPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP 1223
Query: 199 PDAEPGPGAAKGP--PQQKPCMLP 220
P PG G P P P +LP
Sbjct: 1224 PLPPPGTGIPPPPLLPVSGPPLLP 1247
Score = 55.5 bits (132), Expect = 1e-07
Identities = 53/158 (33%), Positives = 59/158 (37%), Gaps = 20/158 (12%)
Query: 83 PRPPEPE---PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPL--VRVPRPVEPPGDLGL 137
P PP P P P PGA P P LP A P PPL +P P PG G+
Sbjct: 1021 PPPPLPGAGIPPPPPLPGAGIPPPPP----LP-GAGIPPPPPLPGAGIPPPPPLPG-AGI 1074
Query: 138 PTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSD 197
P P G P P PPLP + + P A PPP P A P
Sbjct: 1075 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG-AGIP--- 1130
Query: 198 PPDAEPGPGAAKGPPQQK-----PCMLPVRCVPAPATL 230
PP PG G PP + P LP +P P L
Sbjct: 1131 PPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Score = 55.1 bits (131), Expect = 2e-07
Identities = 50/154 (32%), Positives = 56/154 (36%), Gaps = 21/154 (13%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPR----SASAPGAPPL--VRVPRPVEPPGDLG 136
P PP P P PP P P + +LP A P PPL +P P PG G
Sbjct: 909 PPPPPPLPGAGIPP----PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPG-AG 963
Query: 137 LPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCS 196
+P P G P P PPLP + P A PPP P A P
Sbjct: 964 IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIP-- 1020
Query: 197 DPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
PP PG G PP LP +P P L
Sbjct: 1021 -PPPPLPGAGIPPPPP------LPGAGIPPPPPL 1047
Score = 54.7 bits (130), Expect = 2e-07
Identities = 53/153 (34%), Positives = 57/153 (37%), Gaps = 21/153 (13%)
Query: 83 PRPPEPE---PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPL--VRVPRPVEPPGDLGL 137
P PP P P P PGAA P P LP A P PPL +P P PG G+
Sbjct: 933 PLPPLPGAGIPPPPPLPGAAIPPPPP----LP-GAGIPLPPPLPGAGIPPPPPLPG-AGI 986
Query: 138 PTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSD 197
P P G P P PPLP + P A PPP P A P
Sbjct: 987 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIP--- 1042
Query: 198 PPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
PP PG G PP LP +P P L
Sbjct: 1043 PPPPLPGAGIPPPPP------LPGAGIPPPPPL 1069
Score = 53.9 bits (128), Expect = 4e-07
Identities = 52/153 (33%), Positives = 56/153 (36%), Gaps = 21/153 (13%)
Query: 83 PRPPEPE---PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPL--VRVPRPVEPPGDLGL 137
P PP P P P PGA P P LP A P PPL +P P PG G+
Sbjct: 955 PPPPLPGAGIPLPPPLPGAGIPPPPP----LP-GAGIPPPPPLPGAGIPPPPPLPG-AGI 1008
Query: 138 PTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSD 197
P P G P P PPLP + P A PPP P A P
Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIP--- 1064
Query: 198 PPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
PP PG G PP LP +P P L
Sbjct: 1065 PPPPLPGAGIPPPPP------LPGAGIPPPPPL 1091
Score = 52.4 bits (124), Expect = 1e-06
Identities = 67/225 (29%), Positives = 78/225 (34%), Gaps = 39/225 (17%)
Query: 83 PRPPEPE---PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPL--VRVPRPVEPPGDLGL 137
P PP P P P PGA P P LP A P PPL +P P PG +G+
Sbjct: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPP----LP-GAGIPPPPPLPGAGIPPPPPLPG-VGI 1107
Query: 138 PTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSD 197
P P G P P PPLP + P PPP P A P
Sbjct: 1108 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPG-AGIP--- 1163
Query: 198 PPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLR 257
PP PG G PP LP +P P L PG+ P PL
Sbjct: 1164 PPPPLPGAGIPPPPP------LPGVGIPPPPPL------PGV-------GIPPPPPLPGA 1204
Query: 258 RLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPP 302
+ G+G+ P +P L P P LP + PP
Sbjct: 1205 GIPPPPPLPGMGIPPAPAPPL-----PPPGTGIPPPPLLPVSGPP 1244
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/136 (31%), Positives = 50/136 (36%), Gaps = 20/136 (14%)
Query: 105 PTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEP----------QDTPGGPASEPAQ 154
P+ LP + S+ P L VP P P + +PT P Q T P P
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 155 PPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQ 214
P PPLP + P A PPP P AA P PP PG G PP
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPG-AAIP---PPPPLPGAGIPLPPP-- 969
Query: 215 KPCMLPVRCVPAPATL 230
LP +P P L
Sbjct: 970 ----LPGAGIPPPPPL 981
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/159 (30%), Positives = 53/159 (33%), Gaps = 25/159 (15%)
Query: 86 PEPEPAPF-----GPPGAAAQPSKP------TSTVLPRSASAPGAPPLV---RVPRPVEP 131
P P P P PG P P T LP S + P PPL +P P P
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLP-STAIPQPPPLQGTEMLPPPPPP 914
Query: 132 PGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEA 191
G+P P G P P PPLP + P A PP P A
Sbjct: 915 LPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPG-A 973
Query: 192 ASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATL 230
P PP PG G PP LP +P P L
Sbjct: 974 GIP---PPPPLPGAGIPPPPP------LPGAGIPPPPPL 1003
Score = 40.8 bits (94), Expect = 0.003
Identities = 46/183 (25%), Positives = 65/183 (35%), Gaps = 22/183 (12%)
Query: 79 LRKKPRPPEPEPAPFGPPGA------AAQPS---KPTSTVLPRSASAPGAPPLVRVPRPV 129
L +PR P+ P+P G P + AAQP+ P+ST P + PG PV
Sbjct: 283 LAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEE---AAGAPV 339
Query: 130 EPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPS 189
GD T+ + P PGE A P + Q + A P AP+
Sbjct: 340 RGAGD----TDEEGEEDAFEDAPRGSPGEEWA--PEVGEDAPQRLGEEPEEEAQGPDAPA 393
Query: 190 EAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSP 249
A+ P S P K P PC + + ++ P ++ P P
Sbjct: 394 AASLPGSPAPSQR----CFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
Query: 250 RSS 252
S
Sbjct: 450 SLS 452
Score = 37.7 bits (86), Expect = 0.027
Identities = 43/164 (26%), Positives = 51/164 (31%), Gaps = 33/164 (20%)
Query: 85 PPEPE---PAPFGPPGAAAQPSKPT----------STVLPRSASAPGAPPLVRVPRPVEP 131
PP P A G PG+ S T S+ S + P PPL
Sbjct: 811 PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM 870
Query: 132 PGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEA 191
PG +P P PG P LP+ + Q + PPP P
Sbjct: 871 PGLGMVPPPPPPLPGMTV-------------PTLPSTAIPQPPPLQGTEMLPPPPPPLPG 917
Query: 192 ASPCSDPPDAEPGPGAAKGPPQ-----QKPCMLPVRCVPAPATL 230
A PP PG G PP P LP +P P L
Sbjct: 918 AG--IPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL 959
Score = 37.0 bits (84), Expect = 0.047
Identities = 40/121 (33%), Positives = 45/121 (37%), Gaps = 25/121 (20%)
Query: 83 PRPPEPE---PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPL--VRVPRPVEPPGDLGL 137
P PP P P P PGA P P V P PPL V +P P PG G+
Sbjct: 1153 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGV-----GIPPPPPLPGVGIPPPPPLPG-AGI 1206
Query: 138 PTEP----QDTPGGPASEPAQPPGERSADPPL------PALELAQATERPSADAA---PP 184
P P P PA P PPG PPL P L ++ P+ PP
Sbjct: 1207 PPPPPLPGMGIPPAPA-PPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPP 1265
Query: 185 P 185
P
Sbjct: 1266 P 1266
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 60.5 bits (145), Expect = 4e-09
Identities = 45/139 (32%), Positives = 52/139 (37%), Gaps = 13/139 (9%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPL---VRVPRPVEPPGDLGLPT 139
P PP P P P PG S P+ LP + PPL +P P P +G+P+
Sbjct: 600 PPPPPPPPPPPPLPGGVCISSPPS---LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS 656
Query: 140 EPQDTPGGPASEPAQP-PGERSADPPLPALELAQATERPSAD-----AAPPPRAPSEAAS 193
P PGG A P P PG PP P L + P PPP P
Sbjct: 657 -PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP 715
Query: 194 PCSDPPDAEPGPGAAKGPP 212
PP GPG PP
Sbjct: 716 GIPPPPPFPGGPGIPPPPP 734
Score = 57.0 bits (136), Expect = 4e-08
Identities = 38/96 (39%), Positives = 44/96 (45%), Gaps = 13/96 (13%)
Query: 83 PRPPEPE----PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVR----VPRPVEP-PG 133
P PP PE P+P PG A P P LP SA P PP + +P P P PG
Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPP---LPGSARIPPPPPPLPGSAGIPPPPPPLPG 700
Query: 134 DLGLPTEPQDTPGGPASEPAQP-PGERSADPPLPAL 168
+ G+P P PGGP P P PG PP P +
Sbjct: 701 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGM 736
Score = 53.9 bits (128), Expect = 4e-07
Identities = 48/156 (30%), Positives = 51/156 (32%), Gaps = 42/156 (26%)
Query: 83 PRPPEPEPAPFG---------PPGAAAQPSKPTSTVLPRSASAPGAPPL----------- 122
P PP P P P G P G A P P S A+ P PPL
Sbjct: 604 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG----DATIPPPPPLPEGVGIPSPSS 659
Query: 123 ----VRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPP--GERSADPPLPALELAQATER 176
+P P PG +P P PG P PP GE PP P L
Sbjct: 660 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL-------- 711
Query: 177 PSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPP 212
P PPP P P PP PG G PP
Sbjct: 712 PGGPGIPPP--PPFPGGPGIPPP--PPGMGMPPPPP 743
Score = 49.3 bits (116), Expect = 9e-06
Identities = 53/179 (29%), Positives = 62/179 (34%), Gaps = 34/179 (18%)
Query: 69 KELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRP 128
KE+ + + P P P P PP + T++P P AP P P
Sbjct: 551 KEMASLSAAAITVPPSVPSRAPVPPAPPLPG-----DSGTIIP----PPPAPGDSTTPPP 601
Query: 129 VEPPGDLGLPTEPQDTPGGPA-SEPAQPPGERSADPPLPALELAQATERPSADAA--PPP 185
PP P P PGG S P PG + PP P S DA PPP
Sbjct: 602 PPPP-----PPPPPPLPGGVCISSPPSLPGGTAISPPPPL----------SGDATIPPPP 646
Query: 186 RAPSEAA--SPCSDP-----PDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEP 237
P SP S P P P PG+A+ PP P P P L A P
Sbjct: 647 PLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP 705
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/187 (27%), Positives = 63/187 (33%), Gaps = 27/187 (14%)
Query: 66 AVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPG------- 118
A V +L G + L K+ + E A PS P+ +P + PG
Sbjct: 530 AEVSQLTG-EVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIP 588
Query: 119 ---------APPLVRVPRPVEPPGDLGL-PTEPQDTPGGPASEPAQPPGERSADPPLPAL 168
PP P P PP G+ + P PGG A P P + PP P L
Sbjct: 589 PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL 648
Query: 169 ELAQATERPSA-----DAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRC 223
PS+ PPP P A PP P PG+A PP P
Sbjct: 649 PEGVGIPSPSSLPGGTAIPPPPPLPGSARI----PPPPPPLPGSAGIPPPPPPLPGEAGM 704
Query: 224 VPAPATL 230
P P L
Sbjct: 705 PPPPPPL 711
Score = 47.4 bits (111), Expect = 3e-05
Identities = 47/158 (29%), Positives = 60/158 (37%), Gaps = 19/158 (12%)
Query: 113 SASAPGAPPLVRVPRPVEP----PGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLP-A 167
SA+A PP V PV P PGD G P P G ++ P PP PPLP
Sbjct: 557 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAP-GDSTTPPPPPPPPPPPPPLPGG 615
Query: 168 LELAQATERPSADA-APPPRAPSEAASPCSDP---------PDAEPGPGAAKGPPQQKP- 216
+ ++ P A +PPP +A P P P + PG G A PP P
Sbjct: 616 VCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG-GTAIPPPPPLPG 674
Query: 217 -CMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSP 253
+P P P + + P L + P P P
Sbjct: 675 SARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 712
Score = 35.8 bits (81), Expect = 0.10
Identities = 28/80 (35%), Positives = 31/80 (38%), Gaps = 8/80 (10%)
Query: 83 PRPPEPEPAPFGPP-----GAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGL 137
P PP P A PP G A P P LP P PP P PP +G+
Sbjct: 681 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPP--LPGGPGIPPPPPFPGGPGIPPPPPGMGM 738
Query: 138 PTEPQDTPGGPASEPAQPPG 157
P P G PA+ P P G
Sbjct: 739 PPPPPFGFGVPAA-PVLPFG 757
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 60.5 bits (145), Expect = 4e-09
Identities = 45/139 (32%), Positives = 52/139 (37%), Gaps = 13/139 (9%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPL---VRVPRPVEPPGDLGLPT 139
P PP P P P PG S P+ LP + PPL +P P P +G+P+
Sbjct: 609 PPPPPPPPPPPPLPGGVCISSPPS---LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPS 665
Query: 140 EPQDTPGGPASEPAQP-PGERSADPPLPALELAQATERPSAD-----AAPPPRAPSEAAS 193
P PGG A P P PG PP P L + P PPP P
Sbjct: 666 -PSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGP 724
Query: 194 PCSDPPDAEPGPGAAKGPP 212
PP GPG PP
Sbjct: 725 GIPPPPPFPGGPGIPPPPP 743
Score = 57.0 bits (136), Expect = 4e-08
Identities = 38/96 (39%), Positives = 44/96 (45%), Gaps = 13/96 (13%)
Query: 83 PRPPEPE----PAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVR----VPRPVEP-PG 133
P PP PE P+P PG A P P LP SA P PP + +P P P PG
Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPP---LPGSARIPPPPPPLPGSAGIPPPPPPLPG 709
Query: 134 DLGLPTEPQDTPGGPASEPAQP-PGERSADPPLPAL 168
+ G+P P PGGP P P PG PP P +
Sbjct: 710 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGM 745
Score = 53.9 bits (128), Expect = 4e-07
Identities = 48/156 (30%), Positives = 51/156 (32%), Gaps = 42/156 (26%)
Query: 83 PRPPEPEPAPFG---------PPGAAAQPSKPTSTVLPRSASAPGAPPL----------- 122
P PP P P P G P G A P P S A+ P PPL
Sbjct: 613 PPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSG----DATIPPPPPLPEGVGIPSPSS 668
Query: 123 ----VRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPP--GERSADPPLPALELAQATER 176
+P P PG +P P PG P PP GE PP P L
Sbjct: 669 LPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPL-------- 720
Query: 177 PSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPP 212
P PPP P P PP PG G PP
Sbjct: 721 PGGPGIPPP--PPFPGGPGIPPP--PPGMGMPPPPP 752
Score = 49.3 bits (116), Expect = 9e-06
Identities = 53/179 (29%), Positives = 62/179 (34%), Gaps = 34/179 (18%)
Query: 69 KELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRP 128
KE+ + + P P P P PP + T++P P AP P P
Sbjct: 560 KEMASLSAAAITVPPSVPSRAPVPPAPPLPG-----DSGTIIP----PPPAPGDSTTPPP 610
Query: 129 VEPPGDLGLPTEPQDTPGGPA-SEPAQPPGERSADPPLPALELAQATERPSADAA--PPP 185
PP P P PGG S P PG + PP P S DA PPP
Sbjct: 611 PPPP-----PPPPPPLPGGVCISSPPSLPGGTAISPPPPL----------SGDATIPPPP 655
Query: 186 RAPSEAA--SPCSDP-----PDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEP 237
P SP S P P P PG+A+ PP P P P L A P
Sbjct: 656 PLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMP 714
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/187 (27%), Positives = 63/187 (33%), Gaps = 27/187 (14%)
Query: 66 AVVKELDGVKFVVLRKKPRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPG------- 118
A V +L G + L K+ + E A PS P+ +P + PG
Sbjct: 539 AEVSQLTG-EVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPAPPLPGDSGTIIP 597
Query: 119 ---------APPLVRVPRPVEPPGDLGL-PTEPQDTPGGPASEPAQPPGERSADPPLPAL 168
PP P P PP G+ + P PGG A P P + PP P L
Sbjct: 598 PPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDATIPPPPPL 657
Query: 169 ELAQATERPSA-----DAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRC 223
PS+ PPP P A PP P PG+A PP P
Sbjct: 658 PEGVGIPSPSSLPGGTAIPPPPPLPGSARI----PPPPPPLPGSAGIPPPPPPLPGEAGM 713
Query: 224 VPAPATL 230
P P L
Sbjct: 714 PPPPPPL 720
Score = 47.4 bits (111), Expect = 3e-05
Identities = 47/158 (29%), Positives = 60/158 (37%), Gaps = 19/158 (12%)
Query: 113 SASAPGAPPLVRVPRPVEP----PGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLP-A 167
SA+A PP V PV P PGD G P P G ++ P PP PPLP
Sbjct: 566 SAAAITVPPSVPSRAPVPPAPPLPGDSGTIIPPPPAP-GDSTTPPPPPPPPPPPPPLPGG 624
Query: 168 LELAQATERPSADA-APPPRAPSEAASPCSDP---------PDAEPGPGAAKGPPQQKP- 216
+ ++ P A +PPP +A P P P + PG G A PP P
Sbjct: 625 VCISSPPSLPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPG-GTAIPPPPPLPG 683
Query: 217 -CMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSP 253
+P P P + + P L + P P P
Sbjct: 684 SARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP 721
Score = 35.8 bits (81), Expect = 0.10
Identities = 28/80 (35%), Positives = 31/80 (38%), Gaps = 8/80 (10%)
Query: 83 PRPPEPEPAPFGPP-----GAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGL 137
P PP P A PP G A P P LP P PP P PP +G+
Sbjct: 690 PPPPLPGSAGIPPPPPPLPGEAGMPPPPPP--LPGGPGIPPPPPFPGGPGIPPPPPGMGM 747
Query: 138 PTEPQDTPGGPASEPAQPPG 157
P P G PA+ P P G
Sbjct: 748 PPPPPFGFGVPAA-PVLPFG 766
>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
Length = 733
Score = 60.5 bits (145), Expect = 4e-09
Identities = 73/233 (31%), Positives = 89/233 (38%), Gaps = 44/233 (18%)
Query: 91 APFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPG--DLGLPTEPQDT-PGG 147
AP+G PG + + P V+ +P PP P EPP + + T + G
Sbjct: 169 APYGRPGRGLRAATP---VIQACYPSPVGPP---PPPAAEPPSGPEAAVNTHCAELYASG 222
Query: 148 PASEPAQPPGERSADPPLPALELAQ-------ATERPSADAAPPPRAPSEAASPCSDPPD 200
P A ER PL L+L++ A ERP A+ PPR S PP
Sbjct: 223 PGPAAALCASERRCS-PLCGLDLSKKSPPGSAAPERPLAERELPPRPDS--------PPS 273
Query: 201 AEPGPGAAKGPPQQKPCMLPV------RCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPL 254
A GP A K PP P + P+ P R + PG E P P
Sbjct: 274 A--GPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPG-----PEPPGRPDGPS 326
Query: 255 LLRRLSVEESGLG-----LGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPP 302
LL R E GLG LG G SP R R G +SP L APPP
Sbjct: 327 LLYRWMKHEPGLGSYGDELGRERG-SPSERCEERGGDAAVSPGGPPLGLAPPP 378
Score = 35.8 bits (81), Expect = 0.10
Identities = 45/143 (31%), Positives = 55/143 (38%), Gaps = 32/143 (22%)
Query: 95 PPGAAAQPSKPTST--VLPRSASAPGAPPLVRVPRPVEPPGDLGLPTE------PQDTP- 145
PPG+AA P +P + + PR S P A P P+ P LP + P P
Sbjct: 249 PPGSAA-PERPLAERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPF 307
Query: 146 -GGPASEPAQPPGERSADPPL--------PAL-----ELAQATERPS-------ADAAPP 184
GG S +PPG R P L P L EL + PS DAA
Sbjct: 308 RGGSGSPGPEPPG-RPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAVS 366
Query: 185 PRAPSEAASPCSDPPDAEPGPGA 207
P P +P P + GPGA
Sbjct: 367 PGGPPLGLAPPPRYPGSLDGPGA 389
>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
Length = 714
Score = 60.5 bits (145), Expect = 4e-09
Identities = 73/233 (31%), Positives = 89/233 (38%), Gaps = 44/233 (18%)
Query: 91 APFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPG--DLGLPTEPQDT-PGG 147
AP+G PG + + P V+ +P PP P EPP + + T + G
Sbjct: 150 APYGRPGRGLRAATP---VIQACYPSPVGPP---PPPAAEPPSGPEAAVNTHCAELYASG 203
Query: 148 PASEPAQPPGERSADPPLPALELAQ-------ATERPSADAAPPPRAPSEAASPCSDPPD 200
P A ER PL L+L++ A ERP A+ PPR S PP
Sbjct: 204 PGPAAALCASERRCS-PLCGLDLSKKSPPGSAAPERPLAERELPPRPDS--------PPS 254
Query: 201 AEPGPGAAKGPPQQKPCMLPV------RCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPL 254
A GP A K PP P + P+ P R + PG E P P
Sbjct: 255 A--GPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPG-----PEPPGRPDGPS 307
Query: 255 LLRRLSVEESGLG-----LGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPP 302
LL R E GLG LG G SP R R G +SP L APPP
Sbjct: 308 LLYRWMKHEPGLGSYGDELGRERG-SPSERCEERGGDAAVSPGGPPLGLAPPP 359
Score = 35.8 bits (81), Expect = 0.10
Identities = 45/143 (31%), Positives = 55/143 (38%), Gaps = 32/143 (22%)
Query: 95 PPGAAAQPSKPTST--VLPRSASAPGAPPLVRVPRPVEPPGDLGLPTE------PQDTP- 145
PPG+AA P +P + + PR S P A P P+ P LP + P P
Sbjct: 230 PPGSAA-PERPLAERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPF 288
Query: 146 -GGPASEPAQPPGERSADPPL--------PAL-----ELAQATERPS-------ADAAPP 184
GG S +PPG R P L P L EL + PS DAA
Sbjct: 289 RGGSGSPGPEPPG-RPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAVS 347
Query: 185 PRAPSEAASPCSDPPDAEPGPGA 207
P P +P P + GPGA
Sbjct: 348 PGGPPLGLAPPPRYPGSLDGPGA 370
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 59.7 bits (143), Expect = 7e-09
Identities = 61/207 (29%), Positives = 80/207 (38%), Gaps = 37/207 (17%)
Query: 77 VVLRKKPRPPEPEPAPFGP-PGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEP---- 131
VV P P P +P GP PG A P+ P P PP++ +P P P
Sbjct: 294 VVSPSHPPPAPPLGSPPGPKPGFAPPPAPP-----------PPPPPMIGIPPPPPPVGFG 342
Query: 132 -PGDLGLPTEPQDTPGGPASEPAQPPGERSAD-PPLPALELAQATERPSADAAPPPRAPS 189
PG P+ P P + P PP +AD P LP L+Q P+ A PPP P
Sbjct: 343 SPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLSQ----PTGGAPPPPPPPP 398
Query: 190 EAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLR---LRAEEPGLRRQLSEE 246
P PP G PP P +PA + R L A G + + EE
Sbjct: 399 PPGPP---PPPFTGADGQPAIPPPLSDTTKPKSSLPAVSDARSDLLSAIRQGFQLRRVEE 455
Query: 247 PSPRS---------SPLLLRRLSVEES 264
+ + +L RR++VE S
Sbjct: 456 QREQEKRDVVGNDVATILSRRIAVEYS 482
Score = 43.1 bits (100), Expect = 7e-04
Identities = 51/190 (26%), Positives = 64/190 (33%), Gaps = 27/190 (14%)
Query: 83 PRPPEPEPAPFGPPGAAAQ--PSKPTSTVLP---RSASAPGAPPLVRVPRPVEPPGDLGL 137
P PP+ + A P + P P P + S P V P PP L
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
Query: 138 PTEPQDTPG---GPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASP 194
+ P PG PA P PP PP P + T P + + PP P AA P
Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPH-PDFAAPP 365
Query: 195 CSDPPDA------------EPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQ 242
PP A +P GA PP P P P +P +
Sbjct: 366 PPPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPP------PGPPPPPFTGADGQPAIPPP 419
Query: 243 LSEEPSPRSS 252
LS+ P+SS
Sbjct: 420 LSDTTKPKSS 429
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 59.7 bits (143), Expect = 7e-09
Identities = 50/152 (32%), Positives = 56/152 (36%), Gaps = 28/152 (18%)
Query: 85 PPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTE-PQD 143
PP P P P GPP A T LP PGAPP +R PPG GL P+
Sbjct: 405 PPMPGPPPLGPPPAPPLRPPGPPTGLP-PGPPPGAPPFLR------PPGMPGLRGPLPRL 457
Query: 144 TPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEP 203
P GP PPG PP P P PPPR P P + P P
Sbjct: 458 LPPGP------PPGRPPGPPPGPP---------PGLPPGPPPRGPPPRLPPPAPPGIPPP 502
Query: 204 GPGAAKGP-----PQQKPCMLPVRCVPAPATL 230
PG + P P + P +P P L
Sbjct: 503 RPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVL 534
Score = 53.5 bits (127), Expect = 5e-07
Identities = 48/143 (33%), Positives = 55/143 (38%), Gaps = 21/143 (14%)
Query: 94 GPPGAAAQPSKPTSTVLPRSASAP---GAPPLVRVPRP-VEPPGD-LGLPTEPQDTPGGP 148
G A++Q P +V P AP G PPL P P + PPG GLP P PG P
Sbjct: 382 GTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPP--PGAP 439
Query: 149 ASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAA 208
+PPG PLP L PPP P P PP PGP
Sbjct: 440 PF--LRPPGMPGLRGPLPRL----------LPPGPPPGRPP--GPPPGPPPGLPPGPPPR 485
Query: 209 KGPPQQKPCMLPVRCVPAPATLR 231
PP+ P P P P +R
Sbjct: 486 GPPPRLPPPAPPGIPPPRPGMMR 508
Score = 45.1 bits (105), Expect = 2e-04
Identities = 43/136 (31%), Positives = 46/136 (33%), Gaps = 24/136 (17%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQ 142
P P P PF P P +LP PG PP P P PP GLP P
Sbjct: 431 PPGPPPGAPPFLRPPGMPGLRGPLPRLLP-PGPPPGRPP---GPPPGPPP---GLPPGPP 483
Query: 143 DTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAE 202
P P PPG PP P + PP P A P PP
Sbjct: 484 PRGPPPRLPPPAPPG---IPPPRPGM------------MRPPLVPPLGPAPPGLFPPAPL 528
Query: 203 PGPGAAKGPPQ--QKP 216
P PG PP Q+P
Sbjct: 529 PNPGVLSAPPNLIQRP 544
Score = 38.5 bits (88), Expect = 0.016
Identities = 40/126 (31%), Positives = 45/126 (35%), Gaps = 23/126 (18%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEP------PGDLG 136
PR P P P PPG P P LP G PP R+P P P PG +
Sbjct: 455 PRLLPPGPPPGRPPG--PPPGPPPG--LPPGPPPRGPPP--RLPPPAPPGIPPPRPGMMR 508
Query: 137 LPTEPQDTPGGPASEPAQP---PGERSADPPLPALELAQATERPSADAAPPPRAPSEAAS 193
P P P P P P PG SA P L +RP AD +A +
Sbjct: 509 PPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNL--------IQRPKADDTSAATIEKKATA 560
Query: 194 PCSDPP 199
S P
Sbjct: 561 TISAKP 566
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 59.3 bits (142), Expect = 9e-09
Identities = 72/245 (29%), Positives = 88/245 (35%), Gaps = 47/245 (19%)
Query: 94 GPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPA 153
GPP P K S+V S +P PPL P P E G G P GP SEP
Sbjct: 785 GPP---PPPPKRLSSV---SGPSPEPPPLDESPGPKE--GATGPRRRTLSEPAGP-SEPP 835
Query: 154 QPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQ 213
PP P PA + + E P + PP R S P AE G K P
Sbjct: 836 GPPA-----PAGPASDTEE--EEPGPEGTPPSRGSSGEGLPF-----AEEGNLTIKQRP- 882
Query: 214 QKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLG-- 271
KP P R P P PGL L+E + + P R ++ + L G+
Sbjct: 883 -KPAGPPPRETPVP---------PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASA 932
Query: 272 ------------PGRSPHLRRLSRAGPRLLSPDAEELPAAPPPS-AVPLEPSEHEWLVRT 318
PG SP L + P L P AP P+ P+ P L +
Sbjct: 933 TPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESS 992
Query: 319 AGGRW 323
A RW
Sbjct: 993 AASRW 997
Score = 45.1 bits (105), Expect = 2e-04
Identities = 61/246 (24%), Positives = 77/246 (31%), Gaps = 45/246 (18%)
Query: 83 PRPPEPEPAPFGPPGA-------AAQPSKPTSTVLPR----SASAPGAPPLVRVPRPVEP 131
P+ PAP PPGA A P+ P P+ S S PG P
Sbjct: 677 PQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGP 736
Query: 132 PGD-LGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSE 190
G LG PG A P + P + R PPP+ S
Sbjct: 737 VGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSS 796
Query: 191 AASPCSDPPDAEPGPGAAKGP--PQQKPCMLPV-----RCVPAPATLRLRAEEPGLRRQL 243
+ P +PP + PG +G P+++ P PAPA EE
Sbjct: 797 VSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEE------- 849
Query: 244 SEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPS 303
EEP P +P P R L A L+ PA PPP
Sbjct: 850 -EEPGPEGTP------------------PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPR 890
Query: 304 AVPLEP 309
P+ P
Sbjct: 891 ETPVPP 896
Score = 40.4 bits (93), Expect = 0.004
Identities = 59/228 (25%), Positives = 72/228 (31%), Gaps = 64/228 (28%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSK-PTSTVLPRSASAPGAP------------PLVRVPRPV 129
P P PAP GP + P T R +S G P P P P
Sbjct: 831 PSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPR 890
Query: 130 EPPGDLGLP-----------------TEPQDT-----------PGGPASEPAQPPGERSA 161
E P GL EP T PG A P+ PGE
Sbjct: 891 ETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGE--- 947
Query: 162 DPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPG-----AAKGPPQQKP 216
PP +L + + P A P P APS A P P PGPG A++ + +P
Sbjct: 948 SPPASSLPQPEPSSLP-AQGVPTPLAPSPAMQP---PVPPCPGPGLESSAASRWNGETEP 1003
Query: 217 CMLPVRCVPAP-----------ATLRLRAEEPGLRRQLSEEPSPRSSP 253
P + P A +L P L +L P P P
Sbjct: 1004 PAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRP 1051
Score = 37.4 bits (85), Expect = 0.036
Identities = 39/160 (24%), Positives = 53/160 (33%), Gaps = 11/160 (6%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQ 142
P P P P P P A++ P S++ + P AP P PV P GL +
Sbjct: 936 PAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQP-PVPPCPGPGLESSAA 994
Query: 143 DTPGGPASEPAQP------PGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCS 196
G PA P PG +A P+ A P PR P
Sbjct: 995 SRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKL----APRLGPRPVPPPR 1050
Query: 197 DPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEE 236
GPG A+ +Q L A ++ + +E
Sbjct: 1051 PESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQE 1090
Score = 36.2 bits (82), Expect = 0.080
Identities = 30/95 (31%), Positives = 51/95 (53%), Gaps = 12/95 (12%)
Query: 348 TALHWAAKSGDGEMALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVR 407
T LH AAK+G E+ QL+ A +++N ++ G T LH AAL+G + V L++
Sbjct: 109 TPLHLAAKNGHREVIRQLLR------AGIEINRQTKTG-TALHEAALYGKTE-VVRLLLE 160
Query: 408 LGAQVHVRDHSGRRAY----QYLRPGSSYALRRLL 438
G V++R+ + A Q+ +S +++LL
Sbjct: 161 GGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLL 195
Score = 34.7 bits (78), Expect = 0.23
Identities = 23/56 (41%), Positives = 32/56 (57%), Gaps = 6/56 (10%)
Query: 350 LHWAAKSGDGEMALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLV 405
LH+AA G L+ V + R+ A V NA S G PLHLAA +GH + + +L+
Sbjct: 4 LHYAAWQG----RLEPVRLLLRASAAV--NAASLDGQIPLHLAAQYGHYEVSEMLL 53
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 59.3 bits (142), Expect = 9e-09
Identities = 72/245 (29%), Positives = 88/245 (35%), Gaps = 47/245 (19%)
Query: 94 GPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPA 153
GPP P K S+V S +P PPL P P E G G P GP SEP
Sbjct: 867 GPP---PPPPKRLSSV---SGPSPEPPPLDESPGPKE--GATGPRRRTLSEPAGP-SEPP 917
Query: 154 QPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQ 213
PP P PA + + E P + PP R S P AE G K P
Sbjct: 918 GPPA-----PAGPASDTEE--EEPGPEGTPPSRGSSGEGLPF-----AEEGNLTIKQRP- 964
Query: 214 QKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLG-- 271
KP P R P P PGL L+E + + P R ++ + L G+
Sbjct: 965 -KPAGPPPRETPVP---------PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASA 1014
Query: 272 ------------PGRSPHLRRLSRAGPRLLSPDAEELPAAPPPS-AVPLEPSEHEWLVRT 318
PG SP L + P L P AP P+ P+ P L +
Sbjct: 1015 TPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESS 1074
Query: 319 AGGRW 323
A RW
Sbjct: 1075 AASRW 1079
Score = 45.1 bits (105), Expect = 2e-04
Identities = 61/246 (24%), Positives = 77/246 (31%), Gaps = 45/246 (18%)
Query: 83 PRPPEPEPAPFGPPGA-------AAQPSKPTSTVLPR----SASAPGAPPLVRVPRPVEP 131
P+ PAP PPGA A P+ P P+ S S PG P
Sbjct: 759 PQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGP 818
Query: 132 PGD-LGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSE 190
G LG PG A P + P + R PPP+ S
Sbjct: 819 VGSTLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSS 878
Query: 191 AASPCSDPPDAEPGPGAAKGP--PQQKPCMLPV-----RCVPAPATLRLRAEEPGLRRQL 243
+ P +PP + PG +G P+++ P PAPA EE
Sbjct: 879 VSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEE------- 931
Query: 244 SEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPS 303
EEP P +P P R L A L+ PA PPP
Sbjct: 932 -EEPGPEGTP------------------PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPR 972
Query: 304 AVPLEP 309
P+ P
Sbjct: 973 ETPVPP 978
Score = 40.4 bits (93), Expect = 0.004
Identities = 59/228 (25%), Positives = 72/228 (31%), Gaps = 64/228 (28%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSK-PTSTVLPRSASAPGAP------------PLVRVPRPV 129
P P PAP GP + P T R +S G P P P P
Sbjct: 913 PSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPR 972
Query: 130 EPPGDLGLP-----------------TEPQDT-----------PGGPASEPAQPPGERSA 161
E P GL EP T PG A P+ PGE
Sbjct: 973 ETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGE--- 1029
Query: 162 DPPLPALELAQATERPSADAAPPPRAPSEAASPCSDPPDAEPGPG-----AAKGPPQQKP 216
PP +L + + P A P P APS A P P PGPG A++ + +P
Sbjct: 1030 SPPASSLPQPEPSSLP-AQGVPTPLAPSPAMQP---PVPPCPGPGLESSAASRWNGETEP 1085
Query: 217 CMLPVRCVPAP-----------ATLRLRAEEPGLRRQLSEEPSPRSSP 253
P + P A +L P L +L P P P
Sbjct: 1086 PAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRP 1133
Score = 37.7 bits (86), Expect = 0.027
Identities = 29/80 (36%), Positives = 42/80 (52%), Gaps = 7/80 (8%)
Query: 326 QLHGLLLRDRGLAAKRDFMSGFTALHWAAKSGDGEMALQLVEVARRSGAPVDVNARSHGG 385
+L LLL + +D +G LH+AA G L+ V + R+ A V NA S G
Sbjct: 63 ELIALLLEAQATVDIKD-SNGMRPLHYAAWQG----RLEPVRLLLRASAAV--NAASLDG 115
Query: 386 YTPLHLAALHGHEDAAVLLV 405
PLHLAA +GH + + +L+
Sbjct: 116 QIPLHLAAQYGHYEVSEMLL 135
Score = 37.4 bits (85), Expect = 0.036
Identities = 39/160 (24%), Positives = 53/160 (33%), Gaps = 11/160 (6%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQ 142
P P P P P P A++ P S++ + P AP P PV P GL +
Sbjct: 1018 PAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQP-PVPPCPGPGLESSAA 1076
Query: 143 DTPGGPASEPAQP------PGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCS 196
G PA P PG +A P+ A P PR P
Sbjct: 1077 SRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKL----APRLGPRPVPPPR 1132
Query: 197 DPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEE 236
GPG A+ +Q L A ++ + +E
Sbjct: 1133 PESTGTVGPGQAQQRLEQTSSSLAAALRAAEKSIGTKEQE 1172
Score = 36.2 bits (82), Expect = 0.080
Identities = 30/95 (31%), Positives = 51/95 (53%), Gaps = 12/95 (12%)
Query: 348 TALHWAAKSGDGEMALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLVVR 407
T LH AAK+G E+ QL+ A +++N ++ G T LH AAL+G + V L++
Sbjct: 191 TPLHLAAKNGHREVIRQLLR------AGIEINRQTKTG-TALHEAALYGKTE-VVRLLLE 242
Query: 408 LGAQVHVRDHSGRRAY----QYLRPGSSYALRRLL 438
G V++R+ + A Q+ +S +++LL
Sbjct: 243 GGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLL 277
Score = 35.8 bits (81), Expect = 0.10
Identities = 26/75 (34%), Positives = 36/75 (48%), Gaps = 7/75 (9%)
Query: 346 GFTALHWAAKSGDGEMALQLVEVARRSGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLV 405
GF+ALH AA G E+ L+E A V+ + G PLH AA G + V L+
Sbjct: 49 GFSALHHAALGGSLELIALLLE------AQATVDIKDSNGMRPLHYAAWQGRLE-PVRLL 101
Query: 406 VRLGAQVHVRDHSGR 420
+R A V+ G+
Sbjct: 102 LRASAAVNAASLDGQ 116
Score = 29.6 bits (65), Expect = 7.5
Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 8/80 (10%)
Query: 353 AAKSGDGEMALQLVEVARR-------SGAPVDVNARSHGGYTPLHLAALHGHEDAAVLLV 405
A K+GD +LV + S ++VN + G++ LH AAL G + + L+
Sbjct: 10 AVKNGDVTGVQKLVAKVKATKTKLLGSTKRLNVNYQDADGFSALHHAALGGSLE-LIALL 68
Query: 406 VRLGAQVHVRDHSGRRAYQY 425
+ A V ++D +G R Y
Sbjct: 69 LEAQATVDIKDSNGMRPLHY 88
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 58.9 bits (141), Expect = 1e-08
Identities = 63/237 (26%), Positives = 75/237 (31%), Gaps = 27/237 (11%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVP----RPVEPPGDLGLP 138
P+PP P P P Q +P P P PP P +P PP D P
Sbjct: 56 PKPPIPPPPPH------QQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKP 109
Query: 139 TEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSEAASPCSDP 198
Q PG + PP SA P P A P PPP S +P P
Sbjct: 110 VVAQG-PGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTS---APPGAP 165
Query: 199 PDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRR--QLSEEPSPRSSPLLL 256
P P G PPQ P VP P + PG + ++ P P P
Sbjct: 166 PPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGP--- 222
Query: 257 RRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEPSEHE 313
GL G + PH G R P + PP P SE +
Sbjct: 223 --------GLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRSEEK 271
Score = 50.1 bits (118), Expect = 5e-06
Identities = 59/221 (26%), Positives = 75/221 (33%), Gaps = 50/221 (22%)
Query: 92 PFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPASE 151
P GP G KP P PP + P P +PP P +P P +
Sbjct: 46 PMGP-GPGQSGPKPPIPPPPPHQQQQQPPP--QQPPPQQPP-----PHQPPPHPQPHQQQ 97
Query: 152 PAQPPGERSADP-----PLPALELAQATERPSADAAPPPRAPSEAASPCSDP-PDAEPGP 205
PP + S+ P P PA + A P++ +APP P+ A P S P P P P
Sbjct: 98 QPPPPPQDSSKPVVAQGPGPAPGVGSAP--PASSSAPPATPPTSGAPPGSGPGPTPTPPP 155
Query: 206 GAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLSVEESG 265
PP P P VP T +A P P P + P
Sbjct: 156 AVTSAPPGAPPPTPPSSGVP---TTPPQAGGP--------PPPPAAVP------------ 192
Query: 266 LGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVP 306
GPG P + GP P ++P P P P
Sbjct: 193 -----GPGPGP------KQGPGPGGPKGGKMPGGPKPGGGP 222
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/181 (27%), Positives = 65/181 (35%), Gaps = 34/181 (18%)
Query: 131 PPGDLGLPTEPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPSE 190
PP +GL P GP PG+ PP+P Q ++P PP + P +
Sbjct: 34 PPPGMGL--NQNRGPMGPG------PGQSGPKPPIPPPPPHQQQQQP-----PPQQPPPQ 80
Query: 191 AASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPR 250
P PP +P PP Q V P PA PG+ S P+
Sbjct: 81 QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPA--------PGVG---SAPPASS 129
Query: 251 SSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAPPPSAVPLEPS 310
S+P + SG G GPG +P P + S P PP S VP P
Sbjct: 130 SAP----PATPPTSGAPPGSGPGPTP------TPPPAVTSAPPGAPPPTPPSSGVPTTPP 179
Query: 311 E 311
+
Sbjct: 180 Q 180
>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
sapiens]
Length = 735
Score = 58.2 bits (139), Expect = 2e-08
Identities = 71/243 (29%), Positives = 90/243 (37%), Gaps = 55/243 (22%)
Query: 80 RKKPRPPEPEP-APFGPPGAAAQPSKPTSTVLP-RSASAPGAPPLVR------------- 124
R +P PPEPEP AP G A PS P ++ P R A P R
Sbjct: 35 RPEPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWVLGGAKPAEDT 94
Query: 125 -----VPRPVEPPGDLGLPTEPQDTPGGPASEPAQP-PGERSADPPLPALELAQATERPS 178
VP EP G++ P++ P PA EP P PG ++ P + +
Sbjct: 95 SLGPGVPGTGEPAGEIWYNPIPEEDPRPPAPEPPGPQPGSAESEGLAP---------QGA 145
Query: 179 ADAAPPPRAPSEAASPCSDPPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPG 238
A A+PP +A + PGP +K L R L LR G
Sbjct: 146 APASPPTKASRTKS----------PGPARRLSIKMKKLPELRRR-------LSLRGPRAG 188
Query: 239 LRRQLSEEPSPRSSPLLLRRLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPA 298
R E +P S + L G G GPG + R RAG L D+ E PA
Sbjct: 189 RER---ERAAPAGSVISRYHLDSSVGGPGPAAGPGGT----RSPRAG-YLSDGDSPERPA 240
Query: 299 APP 301
PP
Sbjct: 241 GPP 243
>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
Length = 377
Score = 57.8 bits (138), Expect = 3e-08
Identities = 45/146 (30%), Positives = 58/146 (39%), Gaps = 15/146 (10%)
Query: 85 PPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLV--RVPRPVEPPGDLGLPTEPQ 142
PPE AP P +A + P+S+ P + +AP PP P PP P P
Sbjct: 185 PPETTAAP--PTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPS 242
Query: 143 DTPGGPASEPAQPPGERSADPPLPA---LELAQATERPSADAAPPPRAPSEAASPCSDPP 199
T P S A P E +A PP P+ L+ + A+ P AAPP + + A P S
Sbjct: 243 ATTPAPLSSSAPP--ETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSS--- 297
Query: 200 DAEPGPGAAKGPPQQKPCMLPVRCVP 225
P P P P P P
Sbjct: 298 ---PAPQETTAAPITTPNSSPTTLAP 320
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/159 (30%), Positives = 62/159 (38%), Gaps = 24/159 (15%)
Query: 86 PEPEPAPFGPP-GAAAQPSKPTSTVLPRSASAPGAPPLVRVPRP---VEPPGDLGLPTEP 141
P P+ PP +A P+ P+S+ P + +AP P P P PT P
Sbjct: 160 PAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPP 219
Query: 142 QDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPP--------PRAPSEAAS 193
TP P+S P E +A PP P + T P + +APP P A + S
Sbjct: 220 ATTPAPPSS---SAPPETTAAPPTP----SATTPAPLSSSAPPETTAVPPTPSATTLDPS 272
Query: 194 PCSDPPD---AEPGPGAAKGPPQQKPCMLPVRCVPAPAT 229
S PP+ A P P A P P P AP T
Sbjct: 273 SASAPPETTAAPPTPSATTPAPPSSPA--PQETTAAPIT 309
Score = 53.9 bits (128), Expect = 4e-07
Identities = 56/223 (25%), Positives = 78/223 (34%), Gaps = 58/223 (26%)
Query: 83 PRPPEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRP---VEPPGDLGLPT 139
P P + AP P +A P+ P+S+ P + +AP P P P PT
Sbjct: 160 PAPQDTTAAP--PTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPT 217
Query: 140 EPQDTPGGPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRA--PSEAASPCSD 197
P TP P+S P E +A PP P+ T P + +APP P ++ D
Sbjct: 218 PPATTPAPPSSSA---PPETTAAPPTPSA----TTPAPLSSSAPPETTAVPPTPSATTLD 270
Query: 198 PPDAEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLR 257
P A P PP P PAP + P+P+ +
Sbjct: 271 PSSASAPPETTAAPPT------PSATTPAPPS----------------SPAPQETTA--- 305
Query: 258 RLSVEESGLGLGLGPGRSPHLRRLSRAGPRLLSPDAEELPAAP 300
P +P+ + P L+PD E AAP
Sbjct: 306 -------------APITTPN------SSPTTLAPDTSETSAAP 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,196,296
Number of Sequences: 37866
Number of extensions: 2057073
Number of successful extensions: 33588
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 609
Number of HSP's successfully gapped in prelim test: 2247
Number of HSP's that attempted gapping in prelim test: 13187
Number of HSP's gapped (non-prelim): 12911
length of query: 549
length of database: 18,247,518
effective HSP length: 107
effective length of query: 442
effective length of database: 14,195,856
effective search space: 6274568352
effective search space used: 6274568352
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.