Search of human proteins with 9506931

Search of human proteins with 9506931

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo
sapiens]
         (547 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]  1080   0.0  
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   205   1e-52
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   200   2e-51
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   169   6e-42
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi...   163   4e-40
gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   161   1e-39
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   160   2e-39
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   160   2e-39
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi...   160   4e-39
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   159   5e-39
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   159   8e-39
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   158   1e-38
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi...   157   2e-38
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]            157   2e-38
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]            157   2e-38
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         151   2e-36
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          151   2e-36
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ...   149   5e-36
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap...   149   6e-36
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi...   148   1e-35
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    147   2e-35
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   146   5e-35
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi...   145   1e-34
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi...   145   1e-34
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H...   144   3e-34
gi|8922886 DDX19-like protein [Homo sapiens]                          143   5e-34
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  141   1e-33
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   140   3e-33
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ...   140   3e-33
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ...   137   3e-32

>gi|9506931 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 [Homo sapiens]
          Length = 547

 Score = 1080 bits (2793), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 1   MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAA 60
           MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAA
Sbjct: 1   MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAA 60

Query: 61  YAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSA 120
           YAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSA
Sbjct: 61  YAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSA 120

Query: 121 AEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEEL 180
           AEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEEL
Sbjct: 121 AEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEEL 180

Query: 181 KSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCET 240
           KSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCET
Sbjct: 181 KSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCET 240

Query: 241 EEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHI 300
           EEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHI
Sbjct: 241 EEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHI 300

Query: 301 ISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNF 360
           ISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNF
Sbjct: 301 ISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNF 360

Query: 361 DLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFRM 420
           DLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFRM
Sbjct: 361 DLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFRM 420

Query: 421 EEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPL 480
           EEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPL
Sbjct: 421 EEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPL 480

Query: 481 HPAVVKPHLGHVPDYLVPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPLRSFKHKGKKF 540
           HPAVVKPHLGHVPDYLVPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPLRSFKHKGKKF
Sbjct: 481 HPAVVKPHLGHVPDYLVPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPLRSFKHKGKKF 540

Query: 541 RPTAKPS 547
           RPTAKPS
Sbjct: 541 RPTAKPS 547


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  205 bits (521), Expect = 1e-52
 Identities = 147/467 (31%), Positives = 228/467 (48%), Gaps = 58/467 (12%)

Query: 1   MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAA 60
           +E+ E   F+ +G+   L +A   LGW++PT IQ +AIPLAL+G+D++  A TGSGKT A
Sbjct: 18  VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77

Query: 61  YAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSA 120
           +A+P+L  LL          Q +  LVL PT+ELA Q     + L +  +  V+ A +  
Sbjct: 78  FALPILNALLE-------TPQRLFALVLTPTRELAFQISEQFEALGS--SIGVQSAVIVG 128

Query: 121 AEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEEL 180
             DS+SQ   L +KP +++ TP R++ HL+        +L+ LV+DEAD + +  FE E+
Sbjct: 129 GIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEV 188

Query: 181 KSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCET 240
             +L  +PR  + FL SAT  + VQ L+   L NPV   +  S+    ++LQQ+ +   +
Sbjct: 189 DKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAV-SSKYQTVEKLQQYYIFIPS 247

Query: 241 EEDKFLLLYALLKLSLIRGKS-LLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCH 299
           +     L+Y L +L+   G S ++F +T   + R  L L         L+G++    R  
Sbjct: 248 KFKDTYLVYILNELA---GNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLG 304

Query: 300 IISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLN 359
            +++F       ++ATD                             +RG+D  HV  V+N
Sbjct: 305 SLNKFKAKARSILLATDV---------------------------ASRGLDIPHVDVVVN 337

Query: 360 FDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFR 419
           FD+P   + YIHR GRTARA   G  +TFV   +     +IE L+     G  L  +  +
Sbjct: 338 FDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLI-----GKKLPGFPTQ 392

Query: 420 MEEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFED 466
            +E+     R  +A R   +  +RE           H EK K   ED
Sbjct: 393 DDEVMMLTERVAEAQR-FARMELRE-----------HGEKKKRSRED 427


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  200 bits (509), Expect = 2e-51
 Identities = 142/472 (30%), Positives = 226/472 (47%), Gaps = 44/472 (9%)

Query: 5   EALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIP 64
           E L F+ M L   LL+A+T +G+ +PT IQ+  IP+ L GKD+ A A TG+GKTAA+A+P
Sbjct: 216 ENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFALP 275

Query: 65  MLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDS 124
           +L+ L+++    PV     R LVLVPT+EL  Q  S+ +QLA +C  ++         D 
Sbjct: 276 VLERLIYKPRQAPVT----RVLVLVPTRELGIQVHSVTRQLAQFC--NITTCLAVGGLDV 329

Query: 125 VSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLL 184
            SQ A L   PD+++ TP R++ HL         S+E+L++DEAD +    FEE++K ++
Sbjct: 330 KSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEII 389

Query: 185 CHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDK 244
                  Q  L SAT  ++V+ L  + L NPV + +  +    P   Q+F  +    E  
Sbjct: 390 RMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGD 449

Query: 245 FLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQF 304
              + A L         +LF  T ++++R+ + L    +    L+G L    R   + +F
Sbjct: 450 REAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHGNLSQTQRLEALRRF 509

Query: 305 NQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPP 364
                D ++ATD                             ARG+D   V  V+NF +P 
Sbjct: 510 KDEQIDILVATDV---------------------------AARGLDIEGVKTVINFTMPN 542

Query: 365 TPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPIL-----LPYQFR 419
           T + Y+HR GRTARA   G  ++ V   E+  L +I +      +  IL     L ++ +
Sbjct: 543 TIKHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDK 602

Query: 420 MEEIEGFRYRC------RDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFE 465
           +E++E   Y           M+    Q     RL E  +E +  E  +++F+
Sbjct: 603 IEKMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQ 654


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  169 bits (428), Expect = 6e-42
 Identities = 122/403 (30%), Positives = 193/403 (47%), Gaps = 48/403 (11%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           FE   L   LL  + ++GW +P+ IQE++IP+AL G+D+LARA+ G+GK+ AY IP+L+ 
Sbjct: 98  FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 157

Query: 69  LLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQR 128
           L  +K         ++ +V+VPT+ELA Q    + Q+    ++ +  A V A     + R
Sbjct: 158 LDLKK-------DNIQAMVIVPTRELALQ----VSQICIQVSKHMGGAKVMATTGGTNLR 206

Query: 129 AVLMEKPD---VVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLC 185
             +M   D   VV+ TP RIL  +++   K+ D ++++V+DEAD L S  F + ++ ++ 
Sbjct: 207 DDIMRLDDTVHVVIATPGRILDLIKKGVAKV-DHVQMIVLDEADKLLSQDFVQIMEDIIL 265

Query: 186 HLPRIYQAFLMSATFNEDVQALKELILHNPVTLKL-QESQLPGPDQLQQFQVVCETEEDK 244
            LP+  Q  L SATF   VQ      L  P  + L +E  L G  Q   +     TE  K
Sbjct: 266 TLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEELTLKGVTQYYAY----VTERQK 321

Query: 245 FLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQF 304
              L  L     I  +S++F N+ +R   L   + Q       ++ ++    R  +   F
Sbjct: 322 VHCLNTLFSRLQI-NQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDF 380

Query: 305 NQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPP 364
             G    ++ TD                              RGID   V+ V+NFD P 
Sbjct: 381 RNGLCRNLVCTDL---------------------------FTRGIDIQAVNVVINFDFPK 413

Query: 365 TPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGE 407
             E Y+HR GR+ R  + G+ +  +   ++F+L  IEE L  E
Sbjct: 414 LAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTE 456


>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
           sapiens]
          Length = 483

 Score =  163 bits (412), Expect = 4e-40
 Identities = 149/544 (27%), Positives = 230/544 (42%), Gaps = 80/544 (14%)

Query: 8   GFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQ 67
           GF  +GL   L++    LG  +PT +Q   IP  LEG+D L  A+TGSGKTAA+ +P+LQ
Sbjct: 3   GFAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQ 62

Query: 68  LLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQ 127
            L             +  LVL PT+ELA Q     + L       ++   +    D V+Q
Sbjct: 63  KLSEDP-------YGIFCLVLTPTRELAYQIAEQFRVLGKPLG--LKDCIIVGGMDMVAQ 113

Query: 128 RAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFG---FEEELKSLL 184
              L  KP VV+ TP R+  HL+  +      +  LV+DEAD L   G   F  +L+++L
Sbjct: 114 ALELSRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAIL 173

Query: 185 CHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDK 244
             +P   Q  L SAT  + ++ L+ L  + P   + Q          Q++ +V E  +D 
Sbjct: 174 AAVPARRQTLLFSATLTDTLRELQGLATNQPFFWEAQAPVSTVEQLDQRYLLVPEKVKDA 233

Query: 245 FLL-LYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQ 303
           +L+ L    +        ++F NT +    L + L +FS PT  L+  +  + R   +++
Sbjct: 234 YLVHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKFSFPTVALHSMMKQKERFAALAK 293

Query: 304 FNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP 363
           F    Y  +IATD                             +RG+D   V  V+N + P
Sbjct: 294 FKSSIYRILIATDV---------------------------ASRGLDIPTVQVVINHNTP 326

Query: 364 PTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENRGPILLPYQFRMEEI 423
             P+ YIHR GRTARA   G  +T V   +   +  IEE +  +         +F +EE 
Sbjct: 327 GLPKIYIHRVGRTARAGRQGQAITLVTQYDIHLVHAIEEQIKKKLE-------EFSVEEA 379

Query: 424 EGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFEDNPRDLQLLRHDLPLHPA 483
           E         +  +  Q     R  EIK E  H ++ K   E N R   +L    P   A
Sbjct: 380 E---------VLQILTQVNVVRRECEIKLEAAHFDEKK---EINKRKQLILEGKDPDLEA 427

Query: 484 VVKPHLGHVPDYLVPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPLRSFKHKGKKFRPT 543
             K  L  +             +  + ++K+  + ++ K  ++          G K RP 
Sbjct: 428 KRKAELAKIKQ-----------KNRRFKEKVEETLKRQKAGRA----------GHKGRPP 466

Query: 544 AKPS 547
             PS
Sbjct: 467 RTPS 470


>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  161 bits (408), Expect = 1e-39
 Identities = 115/394 (29%), Positives = 196/394 (49%), Gaps = 40/394 (10%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           F+ M L   LL+ +   G+ +P+ IQ++AI   ++G D++A+A++G+GKTA +AI +LQ 
Sbjct: 34  FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93

Query: 69  L-LHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQ 127
           + L  KAT        + LVL PT+ELA+Q Q ++  L  Y       A +         
Sbjct: 94  IELDLKAT--------QALVLAPTRELAQQIQKVVMALGDYMGASCH-ACIGGTNVRAEV 144

Query: 128 RAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCHL 187
           + + ME P ++VGTP R+   L +  L  +  +++ V+DEAD + S GF++++  +   L
Sbjct: 145 QKLQMEAPHIIVGTPGRVFDMLNRRYLSPK-YIKMFVLDEADEMLSRGFKDQIYDIFQKL 203

Query: 188 PRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLL 247
               Q  L+SAT   DV  + +  + +P+ + +++ +L   + ++QF +  E EE K   
Sbjct: 204 NSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELT-LEGIRQFYINVEREEWKLDT 262

Query: 248 LYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQG 307
           L  L + +L   ++++F+NT  +   L   +         ++G++  + R  I+ +F  G
Sbjct: 263 LCDLYE-TLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSG 321

Query: 308 FYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPE 367
               +I TD                            +ARGID   VS V+N+DLP   E
Sbjct: 322 SSRVLITTDL---------------------------LARGIDVQQVSLVINYDLPTNRE 354

Query: 368 AYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIE 401
            YIHR GR  R    G+ +  V   ++  L  IE
Sbjct: 355 NYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIE 388


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  160 bits (406), Expect = 2e-39
 Identities = 117/388 (30%), Positives = 187/388 (48%), Gaps = 40/388 (10%)

Query: 8   GFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQ 67
           GF+ MGL   + + +   G+  PT IQ K IP+ L+GKD++A ARTGSGKTA + +PM +
Sbjct: 97  GFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156

Query: 68  -LLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVS 126
            L  H   TG       R L+L PT+ELA Q     ++L  +    ++ A +   +    
Sbjct: 157 RLKTHSAQTG------ARALILSPTRELALQTLKFTKELGKFTG--LKTALILGGDRMED 208

Query: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCH 186
           Q A L E PD+++ TP R++    + SLKL+ S+E +V DEAD LF  GF E+L+ ++  
Sbjct: 209 QFAALHENPDIIIATPGRLVHVAVEMSLKLQ-SVEYVVFDEADRLFEMGFAEQLQEIIAR 267

Query: 187 LPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQ-ESQLPGPDQLQQFQVVCETEEDKF 245
           LP  +Q  L SAT  + +       L  PV ++L  +++L   +QL+    +   +    
Sbjct: 268 LPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKL--NEQLKTSFFLVREDTKAA 325

Query: 246 LLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFN 305
           +LL+ L  +   + ++++FV T   +  L   L    +    +   L   +R   +++F 
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385

Query: 306 QGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPT 365
            G    +I TD                             ARG+D   +  V+N+  P  
Sbjct: 386 LGKCSTLIVTDL---------------------------AARGLDIPLLDNVINYSFPAK 418

Query: 366 PEAYIHRAGRTARANNPGIVLTFVLPTE 393
            + ++HR GR ARA   G   + V P E
Sbjct: 419 GKLFLHRVGRVARAGRSGTAYSLVAPDE 446


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  160 bits (406), Expect = 2e-39
 Identities = 117/388 (30%), Positives = 187/388 (48%), Gaps = 40/388 (10%)

Query: 8   GFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQ 67
           GF+ MGL   + + +   G+  PT IQ K IP+ L+GKD++A ARTGSGKTA + +PM +
Sbjct: 97  GFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFE 156

Query: 68  -LLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVS 126
            L  H   TG       R L+L PT+ELA Q     ++L  +    ++ A +   +    
Sbjct: 157 RLKTHSAQTG------ARALILSPTRELALQTLKFTKELGKFTG--LKTALILGGDRMED 208

Query: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCH 186
           Q A L E PD+++ TP R++    + SLKL+ S+E +V DEAD LF  GF E+L+ ++  
Sbjct: 209 QFAALHENPDIIIATPGRLVHVAVEMSLKLQ-SVEYVVFDEADRLFEMGFAEQLQEIIAR 267

Query: 187 LPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQ-ESQLPGPDQLQQFQVVCETEEDKF 245
           LP  +Q  L SAT  + +       L  PV ++L  +++L   +QL+    +   +    
Sbjct: 268 LPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDTKL--NEQLKTSFFLVREDTKAA 325

Query: 246 LLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFN 305
           +LL+ L  +   + ++++FV T   +  L   L    +    +   L   +R   +++F 
Sbjct: 326 VLLHLLHNVVRPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFT 385

Query: 306 QGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPT 365
            G    +I TD                             ARG+D   +  V+N+  P  
Sbjct: 386 LGKCSTLIVTDL---------------------------AARGLDIPLLDNVINYSFPAK 418

Query: 366 PEAYIHRAGRTARANNPGIVLTFVLPTE 393
            + ++HR GR ARA   G   + V P E
Sbjct: 419 GKLFLHRVGRVARAGRSGTAYSLVAPDE 446


>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
           sapiens]
          Length = 670

 Score =  160 bits (404), Expect = 4e-39
 Identities = 119/383 (31%), Positives = 186/383 (48%), Gaps = 47/383 (12%)

Query: 19  LQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLH-----RK 73
           L+A+ ++G++  T IQ K+I   LEG+DLLA A+TGSGKT A+ IP ++L++      R 
Sbjct: 191 LKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRN 250

Query: 74  ATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQRAVLME 133
            TG         L+L PT+ELA Q   ++++L T+      +    +   + +Q+  L  
Sbjct: 251 GTGV--------LILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQK--LGN 300

Query: 134 KPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLPRIYQA 193
             +++V TP R+L H+Q     +  +L+ LV+DEAD +   GFEEELK ++  LP   Q 
Sbjct: 301 GINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQT 360

Query: 194 FLMSATFNEDVQALKELIL-HNPVTLKLQESQLPGP-DQLQQFQVVCETEEDKFLLLYAL 251
            L SAT    V+ L  + L   P+ + + + +     D L+Q  VVC +E+ +FLLL+  
Sbjct: 361 MLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEK-RFLLLFTF 419

Query: 252 LKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYDC 311
           LK +  +   + F + +   Y   L L    +P   ++G+     R     QF       
Sbjct: 420 LKKNRKKKLMVFFSSCMSVKYHYEL-LNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGT 478

Query: 312 VIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYIH 371
           ++ TD                             ARG+D   V  ++ +D P  P+ YIH
Sbjct: 479 LLCTDV---------------------------AARGLDIPEVDWIVQYDPPDDPKEYIH 511

Query: 372 RAGRTARA-NNPGIVLTFVLPTE 393
           R GRTAR  N  G  L  + P E
Sbjct: 512 RVGRTARGLNGRGHALLILRPEE 534


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  159 bits (403), Expect = 5e-39
 Identities = 114/405 (28%), Positives = 204/405 (50%), Gaps = 51/405 (12%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           F+ MGL   LL+ +   G+ +P+ IQ++AI   ++G+D++A++++G+GKTA ++I +LQ 
Sbjct: 40  FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99

Query: 69  LLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVR--VANVSAAEDSVS 126
           L        +  +  + L+L PT+ELA Q Q  +  L  Y        +   +  ED   
Sbjct: 100 L-------DIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDI-- 150

Query: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCH 186
               L     VV GTP R+   +++ SL+ R ++++LV+DEAD + + GF+E++  +  +
Sbjct: 151 --RKLDYGQHVVAGTPGRVFDMIRRRSLRTR-AIKMLVLDEADEMLNKGFKEQIYDVYRY 207

Query: 187 LPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFL 246
           LP   Q  L+SAT   ++  +    + +P+ + ++  +L   + ++QF V  E EE KF 
Sbjct: 208 LPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELT-LEGIKQFFVAVEREEWKFD 266

Query: 247 LLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQ 306
            L  L   +L   ++++F NT  +   L   + + +     ++G++P + R  I+ +F  
Sbjct: 267 TLCDLYD-TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRS 325

Query: 307 GFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTP 366
           G    +I+TD                             ARG+D   VS ++N+DLP   
Sbjct: 326 GASRVLISTDV---------------------------WARGLDVPQVSLIINYDLPNNR 358

Query: 367 EAYIHRAGRTARANNPGIVLTFV--------LPTEQFHLGKIEEL 403
           E YIHR GR+ R    G+ + FV           EQ++  +I+E+
Sbjct: 359 ELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEM 403


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  159 bits (401), Expect = 8e-39
 Identities = 115/393 (29%), Positives = 194/393 (49%), Gaps = 38/393 (9%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           F+ M L   LL+ +   G+ +P+ IQ++AI   ++G D++A+A++G+GKTA +AI +LQ 
Sbjct: 35  FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94

Query: 69  LLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQR 128
           L        +  +  + LVL PT+ELA+Q Q +I  L  Y       A +         +
Sbjct: 95  L-------EIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCH-ACIGGTNVRNEMQ 146

Query: 129 AVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLP 188
            +  E P +VVGTP R+   L +  L  +  +++ V+DEAD + S GF++++  +   L 
Sbjct: 147 KLQAEAPHIVVGTPGRVFDMLNRRYLSPK-WIKMFVLDEADEMLSRGFKDQIYEIFQKLN 205

Query: 189 RIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLL 248
              Q  L+SAT   DV  + +  + +P+ + +++ +L   + ++QF +  E EE K   L
Sbjct: 206 TSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELT-LEGIKQFYINVEREEWKLDTL 264

Query: 249 YALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGF 308
             L + +L   ++++F+NT  +   L   +         L+G++  + R  I+ +F  G 
Sbjct: 265 CDLYE-TLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGS 323

Query: 309 YDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEA 368
              +I TD                            +ARGID   VS V+N+DLP   E 
Sbjct: 324 SRVLITTDL---------------------------LARGIDVQQVSLVINYDLPTNREN 356

Query: 369 YIHRAGRTARANNPGIVLTFVLPTEQFHLGKIE 401
           YIHR GR  R    G+ + FV   ++  L  IE
Sbjct: 357 YIHRIGRGGRFGRKGVAINFVTEEDKRILRDIE 389


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  158 bits (399), Expect = 1e-38
 Identities = 116/398 (29%), Positives = 192/398 (48%), Gaps = 43/398 (10%)

Query: 13  GLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLHR 72
           G+  ++L ++   G+ +PT IQ +AIP  + G+DL+  A+TGSGKT A+ +PM + ++ +
Sbjct: 378 GISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQ 437

Query: 73  KA----TGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQR 128
           ++     GP+       +++ PT+ELA Q     ++ +      +RV  V        Q 
Sbjct: 438 RSLEEGEGPI------AVIMTPTRELALQITKECKKFSK--TLGLRVVCVYGGTGISEQI 489

Query: 129 AVLMEKPDVVVGTPSRILSHLQQDSLKLRD--SLELLVVDEADLLFSFGFEEELKSLLCH 186
           A L    +++V TP R++  L  +S ++ +   +  +V+DEAD +F  GFE ++  ++ +
Sbjct: 490 AELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDN 549

Query: 187 LPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFL 246
           +    Q  + SATF   ++AL   IL  P+ +++    +   D  Q  QV+   EE KFL
Sbjct: 550 VRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQ--QVIVIEEEKKFL 607

Query: 247 LLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQ 306
            L  LL      G  ++FV+  E +  L   L + S P   L+G +    R  II+ F  
Sbjct: 608 KLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKN 667

Query: 307 GFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTP 366
           G    ++AT                              ARG+D  H+  V+N+  P   
Sbjct: 668 GTCKLLVATSV---------------------------AARGLDVKHLILVVNYSCPNHY 700

Query: 367 EAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELL 404
           E Y+HRAGRT RA N G   TF+   +  + G I + L
Sbjct: 701 EDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKAL 738


>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
           sapiens]
          Length = 875

 Score =  157 bits (397), Expect = 2e-38
 Identities = 115/393 (29%), Positives = 191/393 (48%), Gaps = 36/393 (9%)

Query: 4   SEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAI 63
           +E   F    L  + L+ + +  +   T IQ++ I LAL+GKD+L  A+TGSGKT A+ +
Sbjct: 66  NEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLV 125

Query: 64  PMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAED 123
           P+L+ L   + T       +  L++ PT+ELA Q   +++++      D     +   +D
Sbjct: 126 PVLEALYRLQWTST---DGLGVLIISPTRELAYQTFEVLRKVGKN--HDFSAGLIIGGKD 180

Query: 124 SVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSL 183
            +   A  +   +++V TP R+L H+ +        L++LV+DEAD +   GF + + ++
Sbjct: 181 -LKHEAERINNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAV 239

Query: 184 LCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQE-SQLPGPDQLQQFQVVCETEE 242
           + +LP+  Q  L SAT  + V+ L  L L NP  + + E ++   P  L+Q  +VCE ++
Sbjct: 240 IENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQ 299

Query: 243 DKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLE-QFSIPTCVLNGELPLRSRCHII 301
            K  +LY+ L+  L +   + F +  E  Y  R+F   +  +    L+G      R  + 
Sbjct: 300 -KISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVY 358

Query: 302 SQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFD 361
           ++F +     + ATD                             ARG+DF  V+ VL FD
Sbjct: 359 NEFVRKRAAVLFATDI---------------------------AARGLDFPAVNWVLQFD 391

Query: 362 LPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQ 394
            P     YIHRAGRTAR    G  L  +LP+E+
Sbjct: 392 CPEDANTYIHRAGRTARYKEDGEALLILLPSEK 424


>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  157 bits (397), Expect = 2e-38
 Identities = 111/401 (27%), Positives = 188/401 (46%), Gaps = 33/401 (8%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           F H G D +L+  +    +++PT IQ + +P+AL G+D++  A+TGSGKTAA+  PML  
Sbjct: 255 FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIH 314

Query: 69  LLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQR 128
           ++ +K   P        +++ PT+EL +Q  +  ++     A ++R   V        Q 
Sbjct: 315 IMDQKELEP--GDGPIAVIVCPTRELCQQIHAECKRFGK--AYNLRSVAVYGGGSMWEQA 370

Query: 129 AVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLP 188
             L E  ++VV TP R++ H+++ +  L+  +  LV DEAD +F  GFE +++S+  H+ 
Sbjct: 371 KALQEGAEIVVCTPGRLIDHVKKKATNLQ-RVSYLVFDEADRMFDMGFEYQVRSIASHVR 429

Query: 189 RIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLL 248
              Q  L SATF + ++ L   IL +P+ + +Q       + + Q   +  +   K+  L
Sbjct: 430 PDRQTLLFSATFRKKIEKLARDILIDPIRV-VQGDIGEANEDVTQIVEILHSGPSKWNWL 488

Query: 249 YALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGF 308
              L      G  LLFV     +  L   L+Q      +L+G++    R  +IS F +  
Sbjct: 489 TRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKD 548

Query: 309 YDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEA 368
              ++ATD                             ARG+D   +  V+N+D+    + 
Sbjct: 549 IPVLVATDV---------------------------AARGLDIPSIKTVINYDVARDIDT 581

Query: 369 YIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENR 409
           + HR GRT RA   G+  T + P +    G +   L G N+
Sbjct: 582 HTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQ 622


>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
          Length = 938

 Score =  157 bits (397), Expect = 2e-38
 Identities = 111/401 (27%), Positives = 188/401 (46%), Gaps = 33/401 (8%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           F H G D +L+  +    +++PT IQ + +P+AL G+D++  A+TGSGKTAA+  PML  
Sbjct: 255 FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIH 314

Query: 69  LLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQR 128
           ++ +K   P        +++ PT+EL +Q  +  ++     A ++R   V        Q 
Sbjct: 315 IMDQKELEP--GDGPIAVIVCPTRELCQQIHAECKRFGK--AYNLRSVAVYGGGSMWEQA 370

Query: 129 AVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLP 188
             L E  ++VV TP R++ H+++ +  L+  +  LV DEAD +F  GFE +++S+  H+ 
Sbjct: 371 KALQEGAEIVVCTPGRLIDHVKKKATNLQ-RVSYLVFDEADRMFDMGFEYQVRSIASHVR 429

Query: 189 RIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLL 248
              Q  L SATF + ++ L   IL +P+ + +Q       + + Q   +  +   K+  L
Sbjct: 430 PDRQTLLFSATFRKKIEKLARDILIDPIRV-VQGDIGEANEDVTQIVEILHSGPSKWNWL 488

Query: 249 YALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGF 308
              L      G  LLFV     +  L   L+Q      +L+G++    R  +IS F +  
Sbjct: 489 TRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNKVISDFKKKD 548

Query: 309 YDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEA 368
              ++ATD                             ARG+D   +  V+N+D+    + 
Sbjct: 549 IPVLVATDV---------------------------AARGLDIPSIKTVINYDVARDIDT 581

Query: 369 YIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLSGENR 409
           + HR GRT RA   G+  T + P +    G +   L G N+
Sbjct: 582 HTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQ 622


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  151 bits (381), Expect = 2e-36
 Identities = 108/388 (27%), Positives = 180/388 (46%), Gaps = 41/388 (10%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           F H      ++  + D  ++ PT IQ +  PLAL G+D++  A+TGSGKT AY +P +  
Sbjct: 173 FHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVH 232

Query: 69  LLHR----KATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDS 124
           + H+    +  GP+       LVL PT+ELA+Q Q +       C+R ++   +      
Sbjct: 233 INHQPYLERGDGPIC------LVLAPTRELAQQVQQVADDYGK-CSR-LKSTCIYGGAPK 284

Query: 125 VSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLL 184
             Q   L    ++ + TP R++  L+     LR     LV+DEAD +   GFE +++ ++
Sbjct: 285 GPQIRDLERGVEICIATPGRLIDFLESGKTNLR-RCTYLVLDEADRMLDMGFEPQIRKIV 343

Query: 185 CHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVC-ETEED 243
             +    Q  + SAT+ ++V+ L E  L +   + +   +L     + Q   VC E+E+D
Sbjct: 344 DQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKD 403

Query: 244 KFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQ 303
             L+      ++    K+++FV T  R   L   + +   P   ++G+     R  ++++
Sbjct: 404 HKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNE 463

Query: 304 FNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP 363
           F  G    +IATD                             +RG+D   V  V+N+D P
Sbjct: 464 FRSGKAPILIATDV---------------------------ASRGLDVEDVKFVINYDYP 496

Query: 364 PTPEAYIHRAGRTARANNPGIVLTFVLP 391
            + E Y+HR GRTAR+ N G   TF  P
Sbjct: 497 NSSEDYVHRIGRTARSTNKGTAYTFFTP 524


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  151 bits (381), Expect = 2e-36
 Identities = 108/388 (27%), Positives = 180/388 (46%), Gaps = 41/388 (10%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           F H      ++  + D  ++ PT IQ +  PLAL G+D++  A+TGSGKT AY +P +  
Sbjct: 173 FHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVH 232

Query: 69  LLHR----KATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDS 124
           + H+    +  GP+       LVL PT+ELA+Q Q +       C+R ++   +      
Sbjct: 233 INHQPYLERGDGPIC------LVLAPTRELAQQVQQVADDYGK-CSR-LKSTCIYGGAPK 284

Query: 125 VSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLL 184
             Q   L    ++ + TP R++  L+     LR     LV+DEAD +   GFE +++ ++
Sbjct: 285 GPQIRDLERGVEICIATPGRLIDFLESGKTNLR-RCTYLVLDEADRMLDMGFEPQIRKIV 343

Query: 185 CHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVC-ETEED 243
             +    Q  + SAT+ ++V+ L E  L +   + +   +L     + Q   VC E+E+D
Sbjct: 344 DQIRPDRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKD 403

Query: 244 KFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQ 303
             L+      ++    K+++FV T  R   L   + +   P   ++G+     R  ++++
Sbjct: 404 HKLIQLMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNE 463

Query: 304 FNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP 363
           F  G    +IATD                             +RG+D   V  V+N+D P
Sbjct: 464 FRSGKAPILIATDV---------------------------ASRGLDVEDVKFVINYDYP 496

Query: 364 PTPEAYIHRAGRTARANNPGIVLTFVLP 391
            + E Y+HR GRTAR+ N G   TF  P
Sbjct: 497 NSSEDYVHRIGRTARSTNKGTAYTFFTP 524


>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
           [Homo sapiens]
          Length = 406

 Score =  149 bits (377), Expect = 5e-36
 Identities = 88/236 (37%), Positives = 136/236 (57%), Gaps = 10/236 (4%)

Query: 1   MEDSEALGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAA 60
           +E+ E   F+ +G+   L +A   LGW++PT IQ +AIPLAL+G+D++  A TGSGKT A
Sbjct: 18  VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77

Query: 61  YAIPMLQLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSA 120
           +A+P+L  LL          Q +  LVL PT+ELA Q     + L +  +  V+ A +  
Sbjct: 78  FALPILNALLE-------TPQRLFALVLTPTRELAFQISEQFEALGS--SIGVQSAVIVG 128

Query: 121 AEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEEL 180
             DS+SQ   L +KP +++ TP R++ HL+        +L+ LV+DEAD + +  FE E+
Sbjct: 129 GIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEV 188

Query: 181 KSLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQV 236
             +L  +PR  + FL SAT  + VQ L+   L NPV   +  S+    ++LQQ+ +
Sbjct: 189 DKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAV-SSKYQTVEKLQQYYI 243



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 41/121 (33%), Positives = 57/121 (47%), Gaps = 17/121 (14%)

Query: 346 ARGIDFHHVSAVLNFDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLS 405
           +RG+D  HV  V+NFD+P   + YIHR GRTARA   G  +TFV   +     +IE L+ 
Sbjct: 275 SRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLI- 333

Query: 406 GENRGPILLPYQFRMEEIEGFRYRCRDAMRSVTKQAIREARLKEIKEELLHSEKLKTYFE 465
               G  L  +  + +E+     R  +A R   +  +RE           H EK K   E
Sbjct: 334 ----GKKLPGFPTQDDEVMMLTERVAEAQR-FARMELRE-----------HGEKKKRSRE 377

Query: 466 D 466
           D
Sbjct: 378 D 378


>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
           sapiens]
          Length = 483

 Score =  149 bits (376), Expect = 6e-36
 Identities = 119/403 (29%), Positives = 198/403 (49%), Gaps = 49/403 (12%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIP--LALEGKDLLARARTGSGKTAAYAIPML 66
           FE + L   LL+ +  +G++RP+ IQE A+P  LA   ++L+A++++G+GKTAA+ + ML
Sbjct: 99  FEELRLKEELLKGIYAMGFNRPSKIQEMALPMMLAHPPQNLIAQSQSGTGKTAAFVLAML 158

Query: 67  QLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVS 126
             +         +E   + L L PT ELA Q   +++Q+  +C  DV+V  + A   +  
Sbjct: 159 SRV-------NALELFPQCLCLAPTYELALQTGRVVEQMGKFCV-DVQV--MYAIRGNRI 208

Query: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLF-SFGFEEELKSLLC 185
            R   + K  +++GTP  +L    +  L     + + V+DEAD++  + GF +    +  
Sbjct: 209 PRGTDITK-QIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQR 267

Query: 186 HLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKF 245
            LP   Q  L SATF + V    E I+ +P  +KL++ +L   + ++Q+ V+CE  +DK+
Sbjct: 268 ALPSECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELT-LNNIRQYYVLCEHRKDKY 326

Query: 246 LLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFN 305
             L  +   S+  G++++F  T   +  L + + Q      +L+GEL +  R  II +F 
Sbjct: 327 QALCNIYG-SITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFR 385

Query: 306 QGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP-- 363
            G    +I T+                             ARGID   V+ V+NFDLP  
Sbjct: 386 DGKEKVLITTNV---------------------------CARGIDVKQVTIVVNFDLPVK 418

Query: 364 ----PTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEE 402
               P  E Y+HR GRT R    G+    +   E   L KI++
Sbjct: 419 QGEEPDYETYLHRIGRTGRFGKKGLAFNMIEVDELPSLMKIQD 461


>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
           sapiens]
          Length = 600

 Score =  148 bits (373), Expect = 1e-35
 Identities = 113/397 (28%), Positives = 192/397 (48%), Gaps = 45/397 (11%)

Query: 14  LDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLHRK 73
           L P++L A+ +LG+   T +Q   IPL +  KD+ A A TGSGKT A+ IP+L++LL R+
Sbjct: 16  LHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRRE 75

Query: 74  ATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQRAVLME 133
               + +  V  +++ PT+ELA Q   ++     +     ++  +              +
Sbjct: 76  E--KLKKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQ 133

Query: 134 KPDVVVGTPSRI--LSHLQQDSLKLRD---SLELLVVDEADLLFSFGFEEELKSLLCHLP 188
             +++V TP R+  +   + + L L     SL++LV+DEAD L   GFE  + ++L  LP
Sbjct: 134 GGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLP 193

Query: 189 RIYQAFLMSATFNEDVQALKELILHNPVTLKLQE------SQLPGPDQLQQFQVVCETEE 242
           +  +  L SAT  ++V+ L    L NPV + ++E      S    P +L+ + +VC+ +E
Sbjct: 194 KQRRTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADE 253

Query: 243 DKFLLLYALLKLSLIRGKSLLFVNTLE--RSYRLRLFLEQFSIPTCVLNGELPLRSRCHI 300
            KF  L   L+ +  + K L+F +T      Y   L +    +    ++G++  + R  I
Sbjct: 254 -KFNQLVHFLR-NHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIHGKMKYK-RNKI 310

Query: 301 ISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNF 360
             +F +     ++ TD                            +ARGID   V+ VL +
Sbjct: 311 FMEFRKLQSGILVCTDV---------------------------MARGIDIPEVNWVLQY 343

Query: 361 DLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHL 397
           D P    A++HR GRTAR  + G  L F+LP E+ ++
Sbjct: 344 DPPSNASAFVHRCGRTARIGHGGSALVFLLPMEESYI 380


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  147 bits (371), Expect = 2e-35
 Identities = 110/405 (27%), Positives = 189/405 (46%), Gaps = 46/405 (11%)

Query: 7   LGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPML 66
           L F        ++  +    ++ PT IQ +  P+AL G D++  A+TGSGKT +Y +P +
Sbjct: 94  LNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAI 153

Query: 67  QLLLHR----KATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYC-ARDVRVANVSAA 121
             + H+    +  GP+       LVL PT+ELA+Q Q   Q  A YC A  ++   +   
Sbjct: 154 VHINHQPFLERGDGPIC------LVLAPTRELAQQVQ---QVAAEYCRACRLKSTCIYGG 204

Query: 122 EDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELK 181
                Q   L    ++ + TP R++  L+     LR +   LV+DEAD +   GFE +++
Sbjct: 205 APKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTT-YLVLDEADRMLDMGFEPQIR 263

Query: 182 SLLCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVC-ET 240
            ++  +    Q  + SAT+ ++V+ L E  L + + + +   +L     + Q   VC + 
Sbjct: 264 KIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDV 323

Query: 241 EEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHI 300
           E+D+ L+      +S    K+++FV T  R   L   + +   P   ++G+   + R  +
Sbjct: 324 EKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWV 383

Query: 301 ISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNF 360
           +++F  G    +IATD                             +RG+D   V  V+N+
Sbjct: 384 LNEFKHGKAPILIATDV---------------------------ASRGLDVEDVKFVINY 416

Query: 361 DLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGKIEELLS 405
           D P + E YIHR GRTAR+   G   TF  P    ++ ++ +L+S
Sbjct: 417 DYPNSSEDYIHRIGRTARSTKTGTAYTFFTPN---NIKQVSDLIS 458


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  146 bits (368), Expect = 5e-35
 Identities = 112/384 (29%), Positives = 185/384 (48%), Gaps = 38/384 (9%)

Query: 7   LGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPML 66
           + FEH  L   L   +   G+  PT IQ + IP+ L G+D+LA A TGSGKTAA+ +P++
Sbjct: 203 IDFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVI 262

Query: 67  QLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVS 126
              L    T          L+L PT+ELA Q +   ++L +   R   V  V        
Sbjct: 263 MRALFESKT-------PSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL-PLPP 314

Query: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCH 186
           Q   L +   V++ TP R+L  ++Q S++L   ++++VVDEAD +   GF++++  +L +
Sbjct: 315 QLYRLQQHVKVIIATPGRLLDIIKQSSVEL-CGVKIVVVDEADTMLKMGFQQQVLDILEN 373

Query: 187 LPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFL 246
           +P   Q  L+SAT    ++ L   +LHNPV +   E  LP  + ++Q  +  E    K  
Sbjct: 374 IPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCAN-VRQIILWVEDPAKKKK 432

Query: 247 LLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFS-IPTCVLNGELPLRSRCHIISQFN 305
           L   L    L +   L+FV+    +  L   +++ + + +  ++ E     R +I+    
Sbjct: 433 LFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLL 492

Query: 306 QGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPT 365
           +G Y+ V++T   VLG                         RG+D   V  V+NFD+P +
Sbjct: 493 EGDYEVVVSTG--VLG-------------------------RGLDLISVRLVVNFDMPSS 525

Query: 366 PEAYIHRAGRTARANNPGIVLTFV 389
            + Y+H+ GR  R    G  +TF+
Sbjct: 526 MDEYVHQIGRVGRLGQNGTAITFI 549


>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
           sapiens]
          Length = 491

 Score =  145 bits (365), Expect = 1e-34
 Identities = 122/381 (32%), Positives = 191/381 (50%), Gaps = 43/381 (11%)

Query: 14  LDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLHRK 73
           ++ RLLQ + D G+  PT IQ +AIP+ L G++LLA A TGSGKT A++IP+L  L    
Sbjct: 64  INSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPA 123

Query: 74  ATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQRAVLME 133
             G       R L++ PT+ELA Q    + +++      + + +  AA  +        +
Sbjct: 124 NKG------FRALIISPTRELASQIHRELIKISEGTGFRIHMIH-KAAVAAKKFGPKSSK 176

Query: 134 KPDVVVGTPSRILSHLQQDSLKL-RDSLELLVVDEADLLF---SFGFEEELKS--LLCHL 187
           K D++V TP+R++  L+QD   +   S+E LVVDE+D LF     GF ++L S  L C  
Sbjct: 177 KFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTS 236

Query: 188 PRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLL 247
            ++ +A + SATF  DV+   +L L N +++ +  ++    + ++Q  +   +E  K L 
Sbjct: 237 HKVRRA-MFSATFAYDVEQWCKLNLDNVISVSI-GARNSAVETVEQELLFVGSETGKLLA 294

Query: 248 LYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQG 307
           +  L+K        L+FV ++ER+  L   L    I   V++ E   + R + +  F  G
Sbjct: 295 MRELVKKG-FNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAG 353

Query: 308 FYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPE 367
               +I T                           A +ARGIDF  V+ V+N+D P +  
Sbjct: 354 KIWVLICT---------------------------ALLARGIDFKGVNLVINYDFPTSSV 386

Query: 368 AYIHRAGRTARANNPGIVLTF 388
            YIHR GRT RA N G  +TF
Sbjct: 387 EYIHRIGRTGRAGNKGKAITF 407


>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
           sapiens]
          Length = 599

 Score =  145 bits (365), Expect = 1e-34
 Identities = 122/381 (32%), Positives = 191/381 (50%), Gaps = 43/381 (11%)

Query: 14  LDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQLLLHRK 73
           ++ RLLQ + D G+  PT IQ +AIP+ L G++LLA A TGSGKT A++IP+L  L    
Sbjct: 172 INSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLKQPA 231

Query: 74  ATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQRAVLME 133
             G       R L++ PT+ELA Q    + +++      + + +  AA  +        +
Sbjct: 232 NKG------FRALIISPTRELASQIHRELIKISEGTGFRIHMIH-KAAVAAKKFGPKSSK 284

Query: 134 KPDVVVGTPSRILSHLQQDSLKL-RDSLELLVVDEADLLF---SFGFEEELKS--LLCHL 187
           K D++V TP+R++  L+QD   +   S+E LVVDE+D LF     GF ++L S  L C  
Sbjct: 285 KFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDGKTGFRDQLASIFLACTS 344

Query: 188 PRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLL 247
            ++ +A + SATF  DV+   +L L N +++ +  ++    + ++Q  +   +E  K L 
Sbjct: 345 HKVRRA-MFSATFAYDVEQWCKLNLDNVISVSI-GARNSAVETVEQELLFVGSETGKLLA 402

Query: 248 LYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQG 307
           +  L+K        L+FV ++ER+  L   L    I   V++ E   + R + +  F  G
Sbjct: 403 MRELVKKG-FNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAG 461

Query: 308 FYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPE 367
               +I T                           A +ARGIDF  V+ V+N+D P +  
Sbjct: 462 KIWVLICT---------------------------ALLARGIDFKGVNLVINYDFPTSSV 494

Query: 368 AYIHRAGRTARANNPGIVLTF 388
            YIHR GRT RA N G  +TF
Sbjct: 495 EYIHRIGRTGRAGNKGKAITF 515


>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  144 bits (362), Expect = 3e-34
 Identities = 110/390 (28%), Positives = 194/390 (49%), Gaps = 49/390 (12%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLAL--EGKDLLARARTGSGKTAAYAIPML 66
           FE + L P+LLQ V  +G++RP+ IQE A+PL L    ++L+A++++G+GKTAA+ + ML
Sbjct: 94  FEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAML 153

Query: 67  QLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVS 126
             +           +  + L L PT ELA Q   +I+Q+  +   ++++A   A   +  
Sbjct: 154 SQV-------EPANKYPQCLCLSPTYELALQTGKVIEQMGKFYP-ELKLA--YAVRGNKL 203

Query: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSF-GFEEELKSLLC 185
           +R   + +  +V+GTP  +L    +        +++ V+DEAD++ +  G +++   +  
Sbjct: 204 ERGQKISE-QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQR 262

Query: 186 HLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKF 245
            LPR  Q  L SATF + V    + ++ +P  +KL+  +    D ++Q+ V+C + ++KF
Sbjct: 263 MLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREE-ETLDTIKQYYVLCSSRDEKF 321

Query: 246 LLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFN 305
             L  L     I  ++++F +T + +  L   L +      +L+GE+ +  R  +I +F 
Sbjct: 322 QALCNLYGAITI-AQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFR 380

Query: 306 QGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP-- 363
           +G    ++ T+                             ARGID   VS V+NFDLP  
Sbjct: 381 EGKEKVLVTTNV---------------------------CARGIDVEQVSVVINFDLPVD 413

Query: 364 ----PTPEAYIHRAGRTARANNPGIVLTFV 389
               P  E Y+HR GRT R    G+ +  V
Sbjct: 414 KDGNPDNETYLHRIGRTGRFGKRGLAVNMV 443


>gi|8922886 DDX19-like protein [Homo sapiens]
          Length = 478

 Score =  143 bits (360), Expect = 5e-34
 Identities = 110/390 (28%), Positives = 195/390 (50%), Gaps = 49/390 (12%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIP--LALEGKDLLARARTGSGKTAAYAIPML 66
           FE + L P+LLQ V  +G++RP+ IQE A+P  LA   ++L+A++++G+GKTAA+ + ML
Sbjct: 93  FEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVLAML 152

Query: 67  QLLLHRKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVS 126
             +          ++  + L L PT ELA Q   +I+Q+  +   ++++A   A   +  
Sbjct: 153 SRV-------EPSDRYPQCLCLSPTYELALQTGKVIEQMGKFYP-ELKLA--YAVRGNKL 202

Query: 127 QRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSF-GFEEELKSLLC 185
           +R   + +  +V+GTP  +L    +        +++ V+DEAD++ +  G +++   +  
Sbjct: 203 ERGQKISE-QIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQR 261

Query: 186 HLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKF 245
            LPR  Q  L SATF + V    + ++ +P  +KL+  +    D ++Q+ V+C + ++KF
Sbjct: 262 MLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREE-ETLDTIKQYYVLCSSRDEKF 320

Query: 246 LLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFN 305
             L  L     I  ++++F +T + +  L   L +      +L+GE+ +  R  +I +F 
Sbjct: 321 QALCNLYGAITI-AQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFR 379

Query: 306 QGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP-- 363
           +G    ++ T+                             ARGID   VS V+NFDLP  
Sbjct: 380 EGKEKVLVTTNV---------------------------CARGIDVEQVSVVINFDLPVD 412

Query: 364 ----PTPEAYIHRAGRTARANNPGIVLTFV 389
               P  E Y+HR GRT R    G+ +  V
Sbjct: 413 KDGNPDNETYLHRIGRTGRFGKRGLAVNMV 442


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  141 bits (356), Expect = 1e-33
 Identities = 100/386 (25%), Positives = 170/386 (44%), Gaps = 37/386 (9%)

Query: 9   FEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQL 68
           F+ M     +L+ +   G   PT IQ + IP  L G+D++  A TGSGKT  + +P++  
Sbjct: 183 FKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMF 242

Query: 69  LLHRKATGPVVE-QAVRGLVLVPTKELARQAQSMIQQLATYCARD----VRVANVSAAED 123
            L ++   P  + +   GL++ P++ELARQ   +++        D    +R A       
Sbjct: 243 CLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMS 302

Query: 124 SVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSL 183
              Q   +     ++V TP R++  LQ+  + L D    L +DEAD +   GFE +++++
Sbjct: 303 VKEQMETIRHGVHMMVATPGRLMDLLQKKMVSL-DICRYLALDEADRMIDMGFEGDIRTI 361

Query: 184 LCHLPRIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEED 243
             +     Q  L SAT  + +Q   +  L  PVT+ +  +     D +Q+ + V E  + 
Sbjct: 362 FSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYVKEEAK- 420

Query: 244 KFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQ 303
              ++Y L  L       L+F         +  +L    +    ++G      R   I  
Sbjct: 421 ---MVYLLECLQKTPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAIEA 477

Query: 304 FNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLP 363
           F +G  D ++ATD                             ++G+DF  +  V+N+D+P
Sbjct: 478 FREGKKDVLVATDV---------------------------ASKGLDFPAIQHVINYDMP 510

Query: 364 PTPEAYIHRAGRTARANNPGIVLTFV 389
              E Y+HR GRT R+ N GI  TF+
Sbjct: 511 EEIENYVHRIGRTGRSGNTGIATTFI 536


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  140 bits (353), Expect = 3e-33
 Identities = 106/373 (28%), Positives = 171/373 (45%), Gaps = 35/373 (9%)

Query: 16  PRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIP-MLQLLLHRKA 74
           P +++ +   G+ +PT IQ +A P+ L+G DL+  A+TG+GKT  Y +P  + L+L    
Sbjct: 251 PEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSL 310

Query: 75  TGPVVEQAVRGLVLVPTKELARQAQSMIQQLATYCARDVRVANVSAAEDSVSQRAVLMEK 134
            G      +  LVL PT+ELA Q +    +   Y  + +R   V    +   Q   L + 
Sbjct: 311 KGQRNRPGM--LVLTPTRELALQVEG---ECCKYSYKGLRSVCVYGGGNRDEQIEELKKG 365

Query: 135 PDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSLLCHLPRIYQAF 194
            D+++ TP R L+ LQ  +     ++  LV+DEAD +   GFE ++  +L  +    Q  
Sbjct: 366 VDIIIATPGR-LNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPDRQTV 424

Query: 195 LMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCETEEDKFLLLYALLKL 254
           + SAT+   V  L +  L  P+ + +    L     ++Q  ++  TEE+K+  +   L+ 
Sbjct: 425 MTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQ-NIIVTTEEEKWSHMQTFLQS 483

Query: 255 SLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYDCVIA 314
                K ++FV+    +  L   L   +I    L+G+   R R   +  F  G    +IA
Sbjct: 484 MSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRILIA 543

Query: 315 TDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYIHRAG 374
           TD                             +RG+D H V+ V NFD P   E Y+HR G
Sbjct: 544 TDL---------------------------ASRGLDVHDVTHVYNFDFPRNIEEYVHRIG 576

Query: 375 RTARANNPGIVLT 387
           RT RA   G+ +T
Sbjct: 577 RTGRAGRTGVSIT 589


>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
           [Homo sapiens]
          Length = 851

 Score =  140 bits (353), Expect = 3e-33
 Identities = 155/600 (25%), Positives = 257/600 (42%), Gaps = 126/600 (21%)

Query: 9   FEHMGLDPRLLQAV-TDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQ 67
           F  +GL P L+  + T L  S  T +Q+++IP+ LEG+D L R++TGSGKT AY IP++Q
Sbjct: 232 FHELGLHPHLISTINTVLKMSSMTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQ 291

Query: 68  LLLH-----RKATGPVVEQAVRGLVLVPTKELARQAQSMIQQLA---TYCARDVRVANVS 119
            L       +++ GP        LVLVPT+ELA Q+   +Q+L    T+    V    + 
Sbjct: 292 SLQAMESKIQRSDGPY------ALVLVPTRELALQSFDTVQKLLKPFTWIVPGV----LM 341

Query: 120 AAEDSVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEE 179
             E   S++A L +  ++++ TP R++ H++         L  LV DEAD +   GFE++
Sbjct: 342 GGEKRKSEKARLRKGINILISTPGRLVDHIKSTKNIHFSRLRWLVFDEADRILDLGFEKD 401

Query: 180 LKSLLCHLP---RIYQAFLMSATFNEDVQALKELILHNPVTLKL---QESQL-------- 225
           +  +L  +    +  Q  L+SAT  E V  L ++ LH+PV++ +      QL        
Sbjct: 402 ITVILNAVNAECQKRQNVLLSATLTEGVTRLADISLHDPVSISVLDKSHDQLNPKDKAVQ 461

Query: 226 -----PGPDQLQQFQV--------------------------VCETEEDKFLLLYALLKL 254
                P  D+L  F +                           C+ EED+ ++++     
Sbjct: 462 EVCPPPAGDKLDSFAIPESLKQHVTVVPSKLRLVCLAAFILQKCKFEEDQKMVVF-FSSC 520

Query: 255 SLIRGKSLLFVNTLERSYRL----RLFLEQFSIPTCVLNGELPLRSRCHIISQFNQGFYD 310
            L+     LF+ TL  S       +L      +    L+G +    R  +  +F+     
Sbjct: 521 ELVEFHYSLFLQTLLSSSGAPASGQLPSASMRLKFLRLHGGMEQEERTAVFQEFSHSRRG 580

Query: 311 CVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLNFDLPPTPEAYI 370
            ++ TD                             ARG+D   V+ ++ ++ P +P  YI
Sbjct: 581 VLLCTDV---------------------------AARGLDLPQVTWIVQYNAPSSPAEYI 613

Query: 371 HRAGRTARANNPGIVLTFVLPTEQFHLGKI--EELLSGENRGPILLPYQFRMEEIEGFRY 428
           HR GRTAR    G  L  + P+E  ++  +   ++   E +   +L    R +  +G R+
Sbjct: 614 HRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKMEDILCVLTRDDCFKGKRW 673

Query: 429 RCRDAMRSVTKQAIREAR--LKEIKEELLHSEKLKT------------YFEDNPRDLQLL 474
             + +  +V  Q IRE    L+ + E+ +HS + +              +   PR+L+ +
Sbjct: 674 GAQKS-HAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQAYATYPRELKHI 732

Query: 475 RHDLPLHPAVVKPHLGHVPDYL----VPPALRGLVRPHKKRKKLSSSCRKAKRAKSQNPL 530
            H       V   HLGHV         P  L  L R  KKRK         K+ +S++ L
Sbjct: 733 FH-------VRSLHLGHVAKSFGLRDAPRNLSALTR--KKRKAHVKRPDLHKKTQSKHSL 783


>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
           [Homo sapiens]
          Length = 724

 Score =  137 bits (344), Expect = 3e-32
 Identities = 111/400 (27%), Positives = 193/400 (48%), Gaps = 40/400 (10%)

Query: 7   LGFEHMGLDPRLLQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPML 66
           L FE   L   L   +   G+++ T +Q+ +IP+ L G+DL+A A+TGSGKTAA+ +P+L
Sbjct: 288 LTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPIL 347

Query: 67  QLLLHRKATGPVVE--QAVRGLVLVPTKELARQAQSMIQQLA-TYCARDVRVANVSAAED 123
             ++H   T    +  Q    +++ PT+EL  Q     ++ +   C R V +   +    
Sbjct: 348 AHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLGH 407

Query: 124 SVSQRAVLMEKPDVVVGTPSRILSHLQQDSLKLRDSLELLVVDEADLLFSFGFEEELKSL 183
           S+ Q   +++  +++  TP R++  + ++ + L+  ++ LV+DEAD +   GF  E+K L
Sbjct: 408 SIRQ---IVQGCNILCATPGRLMDIIGKEKIGLK-QIKYLVLDEADRMLDMGFGPEMKKL 463

Query: 184 LC--HLP--RIYQAFLMSATFNEDVQALKELILHNPVTLKLQESQLPGPDQLQQFQVVCE 239
           +    +P     Q  + SATF E++Q L    L +   L +   Q+ G  +  Q  V+  
Sbjct: 464 ISCPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKSNY-LFVAVGQVGGACRDVQQTVLQV 522

Query: 240 TEEDKFLLLYALLKLSLIRGKSLLFVNTLERSYRLRLFLEQFSIPTCVLNGELPLRSRCH 299
            +  K   L  +L+ ++   ++++FV T +++  +  FL Q  I T  ++G+   R R  
Sbjct: 523 GQFSKREKLVEILR-NIGDERTMVFVETKKKADFIATFLCQEKISTTSIHGDREQREREQ 581

Query: 300 IISQFNQGFYDCVIATDAEVLGAPVKGKRRGRGPKGDKASDPEAGVARGIDFHHVSAVLN 359
            +  F  G    ++AT                              ARG+D  +V  V+N
Sbjct: 582 ALGDFRFGKCPVLVATSV---------------------------AARGLDIENVQHVIN 614

Query: 360 FDLPPTPEAYIHRAGRTARANNPGIVLTFVLPTEQFHLGK 399
           FDLP T + Y+HR GRT R  N G  ++F       HL +
Sbjct: 615 FDLPSTIDEYVHRIGRTGRCGNTGRAISFFDLESDNHLAQ 654


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,096,793
Number of Sequences: 37866
Number of extensions: 965481
Number of successful extensions: 3201
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 2934
Number of HSP's gapped (non-prelim): 97
length of query: 547
length of database: 18,247,518
effective HSP length: 107
effective length of query: 440
effective length of database: 14,195,856
effective search space: 6246176640
effective search space used: 6246176640
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.