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Search of human proteins with 94681063
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|94681063 bromodomain adjacent to zinc finger domain, 2B
[Homo sapiens]
(2168 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 4298 0.0
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo... 902 0.0
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 142 5e-33
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 114 1e-24
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 110 1e-23
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 106 3e-22
gi|74027251 tripartite motif-containing 33 protein isoform beta ... 100 2e-20
gi|47419911 transcriptional intermediary factor 1 alpha isoform ... 97 2e-19
gi|47419909 transcriptional intermediary factor 1 alpha isoform ... 97 2e-19
gi|148746195 trichohyalin [Homo sapiens] 91 1e-17
gi|74027249 tripartite motif-containing 33 protein isoform alpha... 89 4e-17
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 88 8e-17
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 87 2e-16
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 78 8e-14
gi|148612882 cat eye syndrome chromosome region, candidate 2 [Ho... 78 1e-13
gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens] 76 3e-13
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 75 9e-13
gi|115529449 upstream binding transcription factor, RNA polymera... 74 2e-12
gi|115529451 upstream binding transcription factor, RNA polymera... 74 2e-12
gi|7657671 upstream binding transcription factor, RNA polymerase... 74 2e-12
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 74 2e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 73 3e-12
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 73 3e-12
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 73 3e-12
gi|38788260 bromodomain PHD finger transcription factor isoform ... 73 3e-12
gi|38788274 bromodomain PHD finger transcription factor isoform ... 73 3e-12
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 73 3e-12
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 73 3e-12
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 72 5e-12
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 72 5e-12
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 4298 bits (11147), Expect = 0.0
Identities = 2168/2168 (100%), Positives = 2168/2168 (100%)
Query: 1 MESGERLPSSAASSTTPTSSSTPSVASVVSKGGLSTGVASLSSTINPCGHLFRTAGDQPF 60
MESGERLPSSAASSTTPTSSSTPSVASVVSKGGLSTGVASLSSTINPCGHLFRTAGDQPF
Sbjct: 1 MESGERLPSSAASSTTPTSSSTPSVASVVSKGGLSTGVASLSSTINPCGHLFRTAGDQPF 60
Query: 61 NLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTD 120
NLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTD
Sbjct: 61 NLSTVSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLASFPGAEWWRTTD 120
Query: 121 AHTRTGATFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSS 180
AHTRTGATFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSS
Sbjct: 121 AHTRTGATFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSS 180
Query: 181 VIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAME 240
VIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAME
Sbjct: 181 VIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAME 240
Query: 241 SSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQ 300
SSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQ
Sbjct: 241 SSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQ 300
Query: 301 VLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQS 360
VLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQS
Sbjct: 301 VLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQS 360
Query: 361 SQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEES 420
SQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEES
Sbjct: 361 SQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEES 420
Query: 421 SLLTSELRSKREQYKQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHP 480
SLLTSELRSKREQYKQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHP
Sbjct: 421 SLLTSELRSKREQYKQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHP 480
Query: 481 NPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTS 540
NPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTS
Sbjct: 481 NPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTS 540
Query: 541 GRRTPGNQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPS 600
GRRTPGNQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPS
Sbjct: 541 GRRTPGNQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPS 600
Query: 601 SKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESD 660
SKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESD
Sbjct: 601 SKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESD 660
Query: 661 SDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGT 720
SDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGT
Sbjct: 661 SDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGT 720
Query: 721 SSSTLTSSPHSGTSKRRRVTDERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKL 780
SSSTLTSSPHSGTSKRRRVTDERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKL
Sbjct: 721 SSSTLTSSPHSGTSKRRRVTDERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKL 780
Query: 781 RQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRA 840
RQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRA
Sbjct: 781 RQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRA 840
Query: 841 MEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQ 900
MEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQ
Sbjct: 841 MEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQ 900
Query: 901 IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR 960
IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR
Sbjct: 901 IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR 960
Query: 961 AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEA 1020
AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEA
Sbjct: 961 AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEA 1020
Query: 1021 RKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRI 1080
RKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRI
Sbjct: 1021 RKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRI 1080
Query: 1081 PGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLV 1140
PGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLV
Sbjct: 1081 PGLVLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLV 1140
Query: 1141 RLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTK 1200
RLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTK
Sbjct: 1141 RLLSAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTK 1200
Query: 1201 AFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHA 1260
AFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHA
Sbjct: 1201 AFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHA 1260
Query: 1261 KKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEED 1320
KKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEED
Sbjct: 1261 KKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEED 1320
Query: 1321 KEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQD 1380
KEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQD
Sbjct: 1321 KEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQD 1380
Query: 1381 RYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAESVQIKEEMFETSGDSLNCSN 1440
RYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAESVQIKEEMFETSGDSLNCSN
Sbjct: 1381 RYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAESVQIKEEMFETSGDSLNCSN 1440
Query: 1441 TDHCEQKEDLKEKDNTNLFLQKPGSFSKLSKLLEVAKMPPESEVMTPKPNAGANGCTLSY 1500
TDHCEQKEDLKEKDNTNLFLQKPGSFSKLSKLLEVAKMPPESEVMTPKPNAGANGCTLSY
Sbjct: 1441 TDHCEQKEDLKEKDNTNLFLQKPGSFSKLSKLLEVAKMPPESEVMTPKPNAGANGCTLSY 1500
Query: 1501 QNSGKHSLGSVQSTATQSNVEKADSNNLFNTGSSGPGKFYSPLPNDQLLKTLTEKNRQWF 1560
QNSGKHSLGSVQSTATQSNVEKADSNNLFNTGSSGPGKFYSPLPNDQLLKTLTEKNRQWF
Sbjct: 1501 QNSGKHSLGSVQSTATQSNVEKADSNNLFNTGSSGPGKFYSPLPNDQLLKTLTEKNRQWF 1560
Query: 1561 SLLPRTPCDDTSLTHADMSTASLVTPQSQPPSKSPSPTPAPLGSSAQNPVGLNPFALSPL 1620
SLLPRTPCDDTSLTHADMSTASLVTPQSQPPSKSPSPTPAPLGSSAQNPVGLNPFALSPL
Sbjct: 1561 SLLPRTPCDDTSLTHADMSTASLVTPQSQPPSKSPSPTPAPLGSSAQNPVGLNPFALSPL 1620
Query: 1621 QVKGGVSMMGLQFCGWPTGVVTSNIPFTSSVPSLGSGLGLSEGNGNSFLTSNVASSKSES 1680
QVKGGVSMMGLQFCGWPTGVVTSNIPFTSSVPSLGSGLGLSEGNGNSFLTSNVASSKSES
Sbjct: 1621 QVKGGVSMMGLQFCGWPTGVVTSNIPFTSSVPSLGSGLGLSEGNGNSFLTSNVASSKSES 1680
Query: 1681 PVPQNEKATSAQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIR 1740
PVPQNEKATSAQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIR
Sbjct: 1681 PVPQNEKATSAQPAAVEVAKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIR 1740
Query: 1741 EKALQKQIQKHLDYITQACLKNKDVAIIELNENEENQVTRDIVENWSVEEQAMEMDLSVL 1800
EKALQKQIQKHLDYITQACLKNKDVAIIELNENEENQVTRDIVENWSVEEQAMEMDLSVL
Sbjct: 1741 EKALQKQIQKHLDYITQACLKNKDVAIIELNENEENQVTRDIVENWSVEEQAMEMDLSVL 1800
Query: 1801 QQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFTKLCKEHDGEFTGEDESSAH 1860
QQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFTKLCKEHDGEFTGEDESSAH
Sbjct: 1801 QQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFTKLCKEHDGEFTGEDESSAH 1860
Query: 1861 ALERKSDNPLDIAVTRLADLERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQ 1920
ALERKSDNPLDIAVTRLADLERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQ
Sbjct: 1861 ALERKSDNPLDIAVTRLADLERNIERRIEEDIAPGLRVWRRALSEARSAAQVALCIQQLQ 1920
Query: 1921 KSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIA 1980
KSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIA
Sbjct: 1921 KSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIA 1980
Query: 1981 KASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEE 2040
KASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEE
Sbjct: 1981 KASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEE 2040
Query: 2041 NTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKV 2100
NTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKV
Sbjct: 2041 NTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKV 2100
Query: 2101 IKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
IKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK
Sbjct: 2101 IKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
Query: 2161 WTDTFKVS 2168
WTDTFKVS
Sbjct: 2161 WTDTFKVS 2168
>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
sapiens]
Length = 1905
Score = 902 bits (2330), Expect = 0.0
Identities = 571/1572 (36%), Positives = 835/1572 (53%), Gaps = 227/1572 (14%)
Query: 677 SSVKSPSMSL-----TGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSST------- 724
SS P++SL ++P+ + + P A + +FL T++
Sbjct: 473 SSAVLPAVSLEVPLTASVTSPKASPVTSPAAAFPTASPANKDVSSFLETTADVEEITGEG 532
Query: 725 LTSSPHSGTSKRRRVTDERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYP 784
LT+S SG RRR+ E+R+PL++GW+RE RI+ R QGE YY PCGK+++Q+P
Sbjct: 533 LTASG-SGDVMRRRIATPEEVRLPLQHGWRREVRIKKGSHRWQGETWYYGPCGKRMKQFP 591
Query: 785 EVIKYLSRNGIMDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGR 844
EVIKYLSRN + + R++FSFS ++ VGDF+E RD P+G+QW L E++ RI+A+ G+
Sbjct: 592 EVIKYLSRNVVHSVRREHFSFSPRMPVGDFFEERDTPEGLQWVQLSAEEIPSRIQAITGK 651
Query: 845 RGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLL 904
RGRP N ++ + +E +++R +GRPP V E L+ D + L+KL+AQE
Sbjct: 652 RGRPRNTEKAKTKEVPKVKRGRGRPPKVKITELLNKTDNRPLKKLEAQET---------- 701
Query: 905 RKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQI 964
L ++++A++AK KK + +++Q+ + ++ Q
Sbjct: 702 --LNEEDKAKIAKSKKKMR------------------------QKVQRGECQTTIQGQ-- 733
Query: 965 LEAKKKKKEEAANAKLLEAEKRIK-EKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKK 1023
A+ K+K+E + K EA+K+ K EKE + + LK + + +++ + + K+
Sbjct: 734 --ARNKRKQETKSLKQKEAKKKSKAEKEKGKTKQEKLKEKVKREKKEKVKM-------KE 784
Query: 1024 AEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGL 1083
EE + K + +K L +R+LE+R+ + + +E+KKP EDMCL D +PLP+ R+PGL
Sbjct: 785 KEEVTKAKPACKADKTLATQRRLEERQRQQMILEEMKKPTEDMCLTDHQPLPDFSRVPGL 844
Query: 1084 VLSGSTFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLL 1143
L FSDCL +V+FL +FGKVLGFD DVP+L VLQEGLL GDS+GEVQDLLVRLL
Sbjct: 845 TLPSGAFSDCLTIVEFLHSFGKVLGFDPAKDVPSLGVLQEGLLCQGDSLGEVQDLLVRLL 904
Query: 1144 SAAVCDPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFMEAHCGQTELTESLKTKAFQ 1203
AA+ DPG + ++ LGE + + + RDNVSEIL+ F+ A+ + L + L+T+ FQ
Sbjct: 905 KAALHDPGFPSYCQSLKILGEKVSEIPLTRDNVSEILRCFLMAYGVEPALCDRLRTQPFQ 964
Query: 1204 AHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDKWVVEGKLRKLRIIHAKKT 1263
A P QKA+VLAFL++EL S +++EIDK ++ MS+ R++KW+VEG+LR+L+ + AK+T
Sbjct: 965 AQPPQQKAAVLAFLVHELNGSTLIINEIDKTLESMSSYRKNKWIVEGRLRRLKTVLAKRT 1024
Query: 1264 GKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKED 1323
G+ + +++ + LG RRR + + G E++E+EE
Sbjct: 1025 GRSE----VEMEGPEECLG-------RRRSSRIME---------ETSGMEEEEEEESIAA 1064
Query: 1324 KKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQDRYR 1383
G++ D + A+S+ ELE+QIEKLSK+Q +R+KL +S LR+V GQDRYR
Sbjct: 1065 VPGRRGR--RDGEVDATASSIPELERQIEKLSKRQLFFRKKLLHSSQMLRAVSLGQDRYR 1122
Query: 1384 RRYWILPQCGGIFVEGMESGEGLEE-IAKEREKLKKAESVQIKEEMFETSGDSLNCSNTD 1442
RRYW+LP GIFVEG E EE I KE + LK A + +F + + T
Sbjct: 1123 RRYWVLPYLAGIFVEGTEGNLVPEEVIKKETDSLKVAAHASLNPALFSMKMELAGSNTTA 1182
Query: 1443 HCEQKEDLKEKDNTNLFLQKPGSFSKLSKLLEV---------AKMPPESEVMTP-KPNAG 1492
+ + + KPGS V A++ PE+++ P +P
Sbjct: 1183 SSPARARGRPRKT------KPGSMQPRHLKSPVRGQDSEQPQAQLQPEAQLHAPAQPQPQ 1236
Query: 1493 ANGCTLSY-----QNSGKHSLGSVQS-----------TATQSNVEKADSNNLFNTGSSGP 1536
S+ Q SLG Q + TQS+ S+ L T S P
Sbjct: 1237 LQLQLQSHKGFLEQEGSPLSLGQSQHDLSQSAFLSWLSQTQSHSSLLSSSVL--TPDSSP 1294
Query: 1537 GKFYSPLPND-------QLLKTLTEKNRQWFSLLPRTPCDDTSLTHADMSTASLVTPQSQ 1589
GK P P+ ++ + WF++ + PC+ P
Sbjct: 1295 GKL-DPAPSQPPEEPEPDEAESSPDPQALWFNISAQMPCN--------------AAPTPP 1339
Query: 1590 PPSKSPSPTPAPLGSSAQNPVGLNPFALSPLQVKGGVSMMGLQFCGWPTGVVT--SNIPF 1647
P PTP+P ++ P+ P A +P +QF P +
Sbjct: 1340 PAVSEDQPTPSPQQLASSKPMN-RPSAANPCS--------PVQFSSTPLAGLAPKRRAGD 1390
Query: 1648 TSSVPSLGSGLGLSEGNGNSFLTSNVASSKSESPVPQNEKATSAQPAAVEVAKPVDFPSP 1707
+P +GLG + G Q E+ Q A
Sbjct: 1391 PGEMPQSPTGLGQPKRRGR----------PPSKFFKQMEQRYLTQLTA------------ 1428
Query: 1708 KPIPEEMQFGWWRIIDPEDLKALLKVLHLRGIREKALQKQIQKHLDYITQACLKNKDVAI 1767
+P+P EM GWW I DPE L A+LK LH RGIREKAL K + KH D++ + CL+ I
Sbjct: 1429 QPVPPEMCSGWWWIRDPEMLDAMLKALHPRGIREKALHKHLNKHRDFLQEVCLRPSADPI 1488
Query: 1768 IELNENEENQVTRDIVENWSVEEQAMEMDLSVLQQVEDLERRVASASLQVKGWMCPEPAS 1827
E + Q + + +WS +E+ E DL+VLQ VE+LE+RV + LQ++GW CP P S
Sbjct: 1489 FEPRQLPAFQ---EGIMSWSPKEKTYETDLAVLQWVEELEQRVIMSDLQIRGWTCPSPDS 1545
Query: 1828 EREDLVYFEHKSFTKLCKEHDGEFTGEDESSAHALERKSDNPLDIAVTRLADLERNIERR 1887
REDL Y EH S + + D + G A +RK+ NPLD+AV RLA LE+N+ERR
Sbjct: 1546 TREDLAYCEHLSDS----QEDITWRGRGREGL-APQRKTTNPLDLAVMRLAALEQNVERR 1600
Query: 1888 --------------------------------IEEDIAPGLRVWRRALSEARSAAQVALC 1915
I +I P +RVWR+ L RSAAQV LC
Sbjct: 1601 YLREPLWPTHEVVLEKALLSTPNGAPEGTTTEISYEITPRIRVWRQTLERCRSAAQVCLC 1660
Query: 1916 IQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFC 1975
+ QL++SIAWEKS+ KV C +CRKGDN+E LLLCDGCD+GCH YCHRPK+ +P+GDWFC
Sbjct: 1661 LGQLERSIAWEKSVNKVTCLVCRKGDNDEFLLLCDGCDRGCHIYCHRPKMEAVPEGDWFC 1720
Query: 1976 PACIA-KASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLK 2034
C+A + G+ + +G+K K G + + E L RG +
Sbjct: 1721 TVCLAQQVEGEFTQKPGFPKRGQK---RKSGYSLNFS-----EGDGRRRRVLLRGRESPA 1772
Query: 2035 KRKMEENTSINLSKQESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLV 2094
++ SK+ + R+ DL C +IL EME+H+ AWPFL PVN +LV
Sbjct: 1773 AGPRYSEEGLSPSKRRRLS-----MRNHHSDLTFCEIILMEMESHDAAWPFLEPVNPRLV 1827
Query: 2095 PGYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMR 2154
GY+++IK PMDFST+RE+L G Y + E FA D LVFDNC+TFNEDDS++G+AGH MR
Sbjct: 1828 SGYRRIIKNPMDFSTMRERLLRGGYTSSEEFAADALLVFDNCQTFNEDDSEVGKAGHIMR 1887
Query: 2155 KYFEKKWTDTFK 2166
++FE +W + ++
Sbjct: 1888 RFFESRWEEFYQ 1899
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 142 bits (357), Expect = 5e-33
Identities = 118/497 (23%), Positives = 212/497 (42%), Gaps = 56/497 (11%)
Query: 1676 SKSESPVPQNEKATSAQPAAVEV--AKPVDFPSPKPIPEEMQFGWWRIIDPEDLKALLKV 1733
S E P+++KA + A++ + P++ Q W+ ++L LL
Sbjct: 947 SGDEDYCPRSKKANLGKNASMNTQHGTATEVAVETTTPKQGQNLWFLCDSQKELDELLNC 1006
Query: 1734 LHLRGIREKALQKQIQK-HLDYITQACLKNK-DVAIIELNENEE--NQVTRDIVENWSVE 1789
LH +GIRE L+++++K + D I L K ++ + + N+E N + D++E V
Sbjct: 1007 LHPQGIRESQLKERLEKRYQDIIHSIHLARKPNLGLKSCDGNQELLNFLRSDLIE---VA 1063
Query: 1790 EQAMEMDLSVLQQVEDLERRVASASLQVKGWMCPEPASEREDLVYFEHKSFTKLCKEHDG 1849
+ + L +++ + E RV S ++K + E ++ + K +
Sbjct: 1064 TRLQKGGLGYVEETSEFEARVISLE-KLKDF--------GECVIALQASVIKKFLQGF-- 1112
Query: 1850 EFTGEDESSAHALERKSDNPLDIAVTRLADLERNIERRIEEDIAPGLRVWRRALSEARSA 1909
A +R+ D A T D E+ + E +A L W+ A+ EA++
Sbjct: 1113 --------MAPKQKRRKLQSEDSAKTEEVDEEKKMVE--EAKVASALEKWKTAIREAQTF 1162
Query: 1910 AQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIP 1969
+++ + + L I W+ S C++CRK ++ L+LCD C+K H +C RP + +P
Sbjct: 1163 SRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVP 1222
Query: 1970 DGDWFCPAC---IAKASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDED-------- 2018
DG+W CPAC A+ + + + ++ ++ + E+ED
Sbjct: 1223 DGEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRL 1282
Query: 2019 -------------SASTSSSLKRGNKDLKKRKMEENTS--INLSKQESFTSVKKPKRDDS 2063
+ S + G K R+ + + E K+ R S
Sbjct: 1283 RPRKTIRGKHSVIPPAARSGRRPGKKPHSTRRSQPKAPPVDDAEVDELVLQTKRSSRRQS 1342
Query: 2064 KDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLE 2123
+L C IL ++ + +WPF PV Y VI PMDF T++ K S G Y +++
Sbjct: 1343 LELQKCEEILHKIVKYRFSWPFREPVTRDEAEDYYDVITHPMDFQTVQNKCSCGSYRSVQ 1402
Query: 2124 TFALDVRLVFDNCETFN 2140
F D++ VF N E +N
Sbjct: 1403 EFLTDMKQVFTNAEVYN 1419
Score = 55.8 bits (133), Expect = 4e-07
Identities = 96/460 (20%), Positives = 185/460 (40%), Gaps = 76/460 (16%)
Query: 978 AKLLEAEKRIKEKEMRR----QQAVLLKHQER-----ERRRQHMMLMKAMEARKKAEEKE 1028
A+LL +E R + E R ++ LL+H++R E +R+ + K E +KK +EK
Sbjct: 503 ARLLSSEDRARLPEELRSLVQKRYELLEHKKRWASMSEEQRKEYLKKKREELKKKLKEKA 562
Query: 1029 RLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGS 1088
+ ++EK +RL K+++ E + L + + L D PE L +
Sbjct: 563 KERREKEMLERLEKQKRYEDQELTGKNLPAFR-------LVD---TPE-------GLPNT 605
Query: 1089 TFSDCLMVVQFLRNFGKVLGFDVNIDVPNLSVLQEGLLNIGDSMGEVQDLLVRLLSAAVC 1148
F D MVV+FL + +L D + +S+++ + G + + +LV LL +
Sbjct: 606 LFGDVAMVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFL-YLNRVLVILLQTLLQ 664
Query: 1149 DPGLITGYKAKTALGEHLLNVGVNRDNVSEILQIFM-----------------------E 1185
D + Y LG L + + +VSE++++ + E
Sbjct: 665 DE-IAEDY---GELGMKLSEIPLTLHSVSELVRLCLRRSDVQEESEGSDTDDNKDSAAFE 720
Query: 1186 AHCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNLRRDK 1245
+ Q E E L+T F T +K +L L + + + SV ++ + L +++
Sbjct: 721 DNEVQDEFLEKLETSEFFELTSEEKLQILTALCHRILMTYSVQDHMETRQQMSAELWKER 780
Query: 1246 WVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDD 1305
V L+ + KK ++ ++ +++ G+ R+K +
Sbjct: 781 LAV------LKEENDKKRAEKQKRKEMEAKNKENGKVENGLGKTDRKK---------EIV 825
Query: 1306 DSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEK------LSKQQS 1359
+ Q D + ED + + E E + +LE+Q E+ + +
Sbjct: 826 KFEPQVDTEAEDMISAVKSRRLLAIQAKKEREIQEREMKVKLERQAEEERIRKHKAAAEK 885
Query: 1360 QYRRKLFDASHSLRSVMFGQDRYRRRYWIL-PQCGGIFVE 1398
++ + A +R G DR RYW+ + G+F+E
Sbjct: 886 AFQEGIAKAKLVMRRTPIGTDRNHNRYWLFSDEVPGLFIE 925
Score = 37.4 bits (85), Expect = 0.16
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 2/51 (3%)
Query: 1275 GEEQHPLGTPTPGRK--RRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKED 1323
GE Q P P R+ R R + +D +DD D+ +E++E+EE++ED
Sbjct: 1224 GEWQCPACQPATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEED 1274
Score = 37.4 bits (85), Expect = 0.16
Identities = 14/25 (56%), Positives = 22/25 (88%)
Query: 600 SSKDSEDSNEDEEEDDEEEDEEDDE 624
+S+DSED DEEE++EEE+EE+++
Sbjct: 1250 ASEDSEDDESDEEEEEEEEEEEEED 1274
Score = 35.4 bits (80), Expect = 0.61
Identities = 12/24 (50%), Positives = 22/24 (91%)
Query: 604 SEDSNEDEEEDDEEEDEEDDEDDE 627
SEDS +DE +++EEE+EE++E+++
Sbjct: 1251 SEDSEDDESDEEEEEEEEEEEEED 1274
Score = 34.7 bits (78), Expect = 1.0
Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 3/92 (3%)
Query: 257 SEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKA-DGQK 315
+E +S DS+D E DEEEE++ EE E+D + + + + H + P A G++
Sbjct: 1246 TEESASEDSEDDESDEEEEEEEEEEEEEDYEVAGLRLRPRKTIRG-KHSVIPPAARSGRR 1304
Query: 316 ATEKAQEKRIHQP-LPLASESQTHSFQSQQKQ 346
+K R QP P +++ Q K+
Sbjct: 1305 PGKKPHSTRRSQPKAPPVDDAEVDELVLQTKR 1336
Score = 33.5 bits (75), Expect = 2.3
Identities = 11/31 (35%), Positives = 23/31 (74%)
Query: 604 SEDSNEDEEEDDEEEDEEDDEDDESDDSQSE 634
+E+S ++ EDDE ++EE++E++E ++ E
Sbjct: 1246 TEESASEDSEDDESDEEEEEEEEEEEEEDYE 1276
Score = 32.7 bits (73), Expect = 4.0
Identities = 31/109 (28%), Positives = 60/109 (55%), Gaps = 8/109 (7%)
Query: 883 AKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMK 942
+K R L +++ AR +++ L +QK+ + E KK+ A M+ EE+RK+ + K +
Sbjct: 500 SKTARLLSSEDRARLPEELRSL--VQKRYELL---EHKKRWASMS-EEQRKEYLKKKREE 553
Query: 943 QQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKE 991
++K+K + R EKE+ + LE +K+ +++ K L A + + E
Sbjct: 554 LKKKLKEKAKERREKEMLER--LEKQKRYEDQELTGKNLPAFRLVDTPE 600
Score = 32.3 bits (72), Expect = 5.2
Identities = 12/47 (25%), Positives = 22/47 (46%)
Query: 599 PSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEG 645
P++ + E+ ED EDDE DE ++ + E + + + G
Sbjct: 1233 PATARRNSRGRNYTEESASEDSEDDESDEEEEEEEEEEEEEDYEVAG 1279
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b
[Homo sapiens]
Length = 1524
Score = 114 bits (284), Expect = 1e-24
Identities = 146/586 (24%), Positives = 240/586 (40%), Gaps = 106/586 (18%)
Query: 926 MAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEK 985
+A+ + KE+ K++KQ+E + + K K K E A+A LEA+K
Sbjct: 297 LASYRSKATKERDKLLKQEEM---------------KSLAFEKAKLKREKADA--LEAKK 339
Query: 986 RIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERK 1045
+ KE ++E++R+ + + E KK EEKERLK E+ E +E+
Sbjct: 340 KEKE--------------DKEKKREELKKIVEEERLKKKEEKERLKVEREKE----REKL 381
Query: 1046 LEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGK 1105
E++R +E K+ KP EDM D K LPE P L F D LMV++FL FG+
Sbjct: 382 REEKRKYVEYLKQWSKPREDMECDDLKELPE-PTPVKTRLPPEIFGDALMVLEFLNAFGE 440
Query: 1106 VLGFDVNIDVPN---LSVLQEGLLNIGDSMGEVQDLLVRLLSA---AVCDPGLITGYKAK 1159
+ FD+ + P+ L VL+E L+ DS G + +LL L+A A+ + +
Sbjct: 441 L--FDLQDEFPDGVTLEVLEEALVG-NDSEGPLCELLFFFLTAIFQAIAEEEEEVAKEQL 497
Query: 1160 T---ALGEHLLNVGVNRDNVSEILQIF------------------------------MEA 1186
T G L ++ ++ +SEIL++ ME
Sbjct: 498 TDADTKGCSLKSLDLDSCTLSEILRLHILASGADVTSANAKYRYQKRGGFDATDDACMEL 557
Query: 1187 HCGQTELTESLKTKAFQAHTPAQKASVLAFLINELACSKSVVSEIDKNIDYMSNL----- 1241
L + L + + TP +K +L L +L S I+ +D +
Sbjct: 558 RLSNPSLVKKLSSTSVYDLTPGEKMKILHALCGKLLTLVSTRDFIEDYVDILRQAKQEFR 617
Query: 1242 -------RRDKWVVEGKLRKLRIIHAKKTGKRDTSGGIDLGEEQHPLGTPTPG-RKRRRK 1293
R+++ ++RK + K+ ++ L E++ T + R+
Sbjct: 618 ELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDEQRNSTADISIGEEERE 677
Query: 1294 GGDSDYDDDDDDDSDDQGDEDDEDEED----KEDKKGKKTDICEDE---DEGDQAASVEE 1346
D+ + D + + D EDE+D K ++GK+ E E + E
Sbjct: 678 DFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKEFTRQEQINCVTREP 737
Query: 1347 LEKQIEKLSKQQSQYR-----RKLFDASHSLRSVMFGQDRYRRRYWILPQCGGIFVEGME 1401
L E+ KQ+ Q + K+ A G+DR RRYWI P G+F+E E
Sbjct: 738 LTADEEEALKQEHQRKEKELLEKIQSAIACTNIFPLGRDRMYRRYWIFPSIPGLFIE--E 795
Query: 1402 SGEGLEEIAKEREKLKKAESVQIKEEMFET-SGDSLNCSNTDHCEQ 1446
GL E +VQ ++ T +G+ L +T + +Q
Sbjct: 796 DYSGLTEDMLLPRPSSFQNNVQSQDPQVSTKTGEPLMSESTSNIDQ 841
Score = 110 bits (276), Expect = 1e-23
Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 5/148 (3%)
Query: 1899 WRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHT 1958
WR +L + S +QV L + L +S+ W KSI+ C+ICRK + E ++LCDGCD+G HT
Sbjct: 1084 WRESLLSSASLSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHT 1143
Query: 1959 YCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLH--VKGKKTNESKKGKKVTLTGDTED 2016
YC RPK+ T+P+GDWFCP C K + L ++ + +S G+ + GD E+
Sbjct: 1144 YCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEE 1203
Query: 2017 EDSASTSSSLKRGNKDLKKRKMEENTSI 2044
S +++ D ++ EE S+
Sbjct: 1204 GQSEEEEYEVEQDEDDSQE---EEEVSL 1228
Score = 73.9 bits (180), Expect = 2e-12
Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 10/155 (6%)
Query: 2007 KVTLTGDTEDEDSASTSSSLKRGNKDLK----KRKMEENTSINLSKQESFTSVKKPKRDD 2062
+V T +E S + +S L + K KR+ E + + L ++ S ++
Sbjct: 1346 RVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSS------GRQGG 1399
Query: 2063 SKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNL 2122
+L+ ++ E+ H+D+WPFL V+ VP Y +IKKP+ + IREK++ +Y
Sbjct: 1400 VHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLA 1459
Query: 2123 ETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYF 2157
F D+ L+F NC +N ++ +AG ++ +F
Sbjct: 1460 SEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFF 1494
Score = 45.4 bits (106), Expect = 6e-04
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 8/126 (6%)
Query: 612 EEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMK 671
E D++ ED EDDE D + E S E E E+D+DD ++E S + + ++
Sbjct: 1181 ESDEDVEDSMGGEDDEVDGDEEEGQSEEE---EYEVEQDEDDSQEEEEVSLPKRGRPQVR 1237
Query: 672 LNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHS 731
L T S S S G + +++ S P S G S + S+P +
Sbjct: 1238 LPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSK-----TGRSLRKINSAPPT 1292
Query: 732 GTSKRR 737
T R
Sbjct: 1293 ETKSLR 1298
Score = 36.6 bits (83), Expect = 0.28
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 1288 RKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEEL 1347
R RR + D+D D G EDDE + D+E+ + ++ + ++DE D S EE
Sbjct: 1168 RSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDD---SQEEE 1224
Query: 1348 EKQIEKLSKQQ 1358
E + K + Q
Sbjct: 1225 EVSLPKRGRPQ 1235
Score = 36.6 bits (83), Expect = 0.28
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 23/116 (19%)
Query: 594 TDSDIPSSKDSEDSNEDEEEDDEEEDEEDDE-DDESDDSQSESD---------------- 636
+D D+ S ED D +E++ + +EE+ E + + DDSQ E +
Sbjct: 1182 SDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVK 1241
Query: 637 ----SNSESDTEGSEEEDD--DDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSL 686
+S + G ++E + Q + T KT L K S+ + + SL
Sbjct: 1242 TRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSL 1297
Score = 33.5 bits (75), Expect = 2.3
Identities = 40/155 (25%), Positives = 75/155 (48%), Gaps = 18/155 (11%)
Query: 901 IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR 960
+ +LR+ KQE + E +++ AA RK+KE+ K+ +Q++K+K Q+ E E R
Sbjct: 606 VDILRQA-KQEFRELKAEQHRKEREEAAARIRKRKEE-KLKEQEQKMKEKQEKLKEDEQR 663
Query: 961 --AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERR---------- 1008
I ++++++ + + + E++ +++M + +R RR
Sbjct: 664 NSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKE 723
Query: 1009 --RQHMMLMKAMEARKKAEEKERLKQE-KRDEKRL 1040
RQ + E A+E+E LKQE +R EK L
Sbjct: 724 FTRQEQINCVTREP-LTADEEEALKQEHQRKEKEL 757
Score = 32.7 bits (73), Expect = 4.0
Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 257 SEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKA 316
S +SS LE DE+ ED E ++ D D E E Q + + D + + + +
Sbjct: 1169 SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGD-EEEGQSEEEEYEVEQDEDDSQEEEEVS 1227
Query: 317 TEKAQEKRIHQPLPLASE-SQTHSFQSQQKQP 347
K ++ P+ + S + S + QQ++P
Sbjct: 1228 LPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEP 1259
Score = 32.0 bits (71), Expect = 6.8
Identities = 17/60 (28%), Positives = 26/60 (43%)
Query: 233 KPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESE 292
K R + + S +S + S G D EE + EE++ E ++DDS E E
Sbjct: 1166 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1225
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a
[Homo sapiens]
Length = 1556
Score = 110 bits (276), Expect = 1e-23
Identities = 54/148 (36%), Positives = 83/148 (56%), Gaps = 5/148 (3%)
Query: 1899 WRRALSEARSAAQVALCIQQLQKSIAWEKSIMKVYCQICRKGDNEELLLLCDGCDKGCHT 1958
WR +L + S +QV L + L +S+ W KSI+ C+ICRK + E ++LCDGCD+G HT
Sbjct: 1116 WRESLLSSASLSQVFLHLSTLDRSVIWSKSILNARCKICRKKGDAENMVLCDGCDRGHHT 1175
Query: 1959 YCHRPKITTIPDGDWFCPACIAKASGQTLKIKKLH--VKGKKTNESKKGKKVTLTGDTED 2016
YC RPK+ T+P+GDWFCP C K + L ++ + +S G+ + GD E+
Sbjct: 1176 YCVRPKLKTVPEGDWFCPECRPKQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEE 1235
Query: 2017 EDSASTSSSLKRGNKDLKKRKMEENTSI 2044
S +++ D ++ EE S+
Sbjct: 1236 GQSEEEEYEVEQDEDDSQE---EEEVSL 1260
Score = 85.9 bits (211), Expect = 4e-16
Identities = 74/223 (33%), Positives = 112/223 (50%), Gaps = 42/223 (18%)
Query: 926 MAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEK 985
+A+ + KE+ K++KQ+E + + K K K E A+A LEA+K
Sbjct: 297 LASYRSKATKERDKLLKQEEM---------------KSLAFEKAKLKREKADA--LEAKK 339
Query: 986 RIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERK 1045
+ KE ++E++R+ + + E KK EEKERLK E+ E +E+
Sbjct: 340 KEKE--------------DKEKKREELKKIVEEERLKKKEEKERLKVEREKE----REKL 381
Query: 1046 LEQRRLELEMAKELKKPNEDMCLADQKPLPELPRIPGLVLSGSTFSDCLMVVQFLRNFGK 1105
E++R +E K+ KP EDM D K LPE P L F D LMV++FL FG+
Sbjct: 382 REEKRKYVEYLKQWSKPREDMECDDLKELPE-PTPVKTRLPPEIFGDALMVLEFLNAFGE 440
Query: 1106 VLGFDVNIDVPN---LSVLQEGLLNIGDSMGEVQDLLVRLLSA 1145
+ FD+ + P+ L VL+E L+ DS G + +LL L+A
Sbjct: 441 L--FDLQDEFPDGVTLEVLEEALVG-NDSEGPLCELLFFFLTA 480
Score = 73.9 bits (180), Expect = 2e-12
Identities = 43/155 (27%), Positives = 78/155 (50%), Gaps = 10/155 (6%)
Query: 2007 KVTLTGDTEDEDSASTSSSLKRGNKDLK----KRKMEENTSINLSKQESFTSVKKPKRDD 2062
+V T +E S + +S L + K KR+ E + + L ++ S ++
Sbjct: 1378 RVIATKSSEQSRSVNIASKLSLQESESKRRCRKRQSPEPSPVTLGRRSS------GRQGG 1431
Query: 2063 SKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNL 2122
+L+ ++ E+ H+D+WPFL V+ VP Y +IKKP+ + IREK++ +Y
Sbjct: 1432 VHELSAFEQLVVELVRHDDSWPFLKLVSKIQVPDYYDIIKKPIALNIIREKVNKCEYKLA 1491
Query: 2123 ETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYF 2157
F D+ L+F NC +N ++ +AG ++ +F
Sbjct: 1492 SEFIDDIELMFSNCFEYNPRNTSEAKAGTRLQAFF 1526
Score = 45.4 bits (106), Expect = 6e-04
Identities = 34/126 (26%), Positives = 52/126 (41%), Gaps = 8/126 (6%)
Query: 612 EEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMK 671
E D++ ED EDDE D + E S E E E+D+DD ++E S + + ++
Sbjct: 1213 ESDEDVEDSMGGEDDEVDGDEEEGQSEEE---EYEVEQDEDDSQEEEEVSLPKRGRPQVR 1269
Query: 672 LNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHS 731
L T S S S G + +++ S P S G S + S+P +
Sbjct: 1270 LPVKTRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSK-----TGRSLRKINSAPPT 1324
Query: 732 GTSKRR 737
T R
Sbjct: 1325 ETKSLR 1330
Score = 36.6 bits (83), Expect = 0.28
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 1288 RKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEEL 1347
R RR + D+D D G EDDE + D+E+ + ++ + ++DE D S EE
Sbjct: 1200 RSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDD---SQEEE 1256
Query: 1348 EKQIEKLSKQQ 1358
E + K + Q
Sbjct: 1257 EVSLPKRGRPQ 1267
Score = 36.6 bits (83), Expect = 0.28
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 23/116 (19%)
Query: 594 TDSDIPSSKDSEDSNEDEEEDDEEEDEEDDE-DDESDDSQSESD---------------- 636
+D D+ S ED D +E++ + +EE+ E + + DDSQ E +
Sbjct: 1214 SDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEEVSLPKRGRPQVRLPVK 1273
Query: 637 ----SNSESDTEGSEEEDD--DDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSL 686
+S + G ++E + Q + T KT L K S+ + + SL
Sbjct: 1274 TRGKLSSSFSSRGQQQEPGRYPSRSQQSTPKTTVSSKTGRSLRKINSAPPTETKSL 1329
Score = 33.5 bits (75), Expect = 2.3
Identities = 40/155 (25%), Positives = 75/155 (48%), Gaps = 18/155 (11%)
Query: 901 IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR 960
+ +LR+ KQE + E +++ AA RK+KE+ K+ +Q++K+K Q+ E E R
Sbjct: 638 VDILRQA-KQEFRELKAEQHRKEREEAAARIRKRKEE-KLKEQEQKMKEKQEKLKEDEQR 695
Query: 961 --AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERR---------- 1008
I ++++++ + + + E++ +++M + +R RR
Sbjct: 696 NSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTEDEDDPGSHKRGRRGKRGQNGFKE 755
Query: 1009 --RQHMMLMKAMEARKKAEEKERLKQE-KRDEKRL 1040
RQ + E A+E+E LKQE +R EK L
Sbjct: 756 FTRQEQINCVTREP-LTADEEEALKQEHQRKEKEL 789
Score = 32.7 bits (73), Expect = 4.0
Identities = 23/92 (25%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 257 SEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKA 316
S +SS LE DE+ ED E ++ D D E E Q + + D + + + +
Sbjct: 1201 SRRLSSRQRPSLESDEDVEDSMGGEDDEVDGD-EEEGQSEEEEYEVEQDEDDSQEEEEVS 1259
Query: 317 TEKAQEKRIHQPLPLASE-SQTHSFQSQQKQP 347
K ++ P+ + S + S + QQ++P
Sbjct: 1260 LPKRGRPQVRLPVKTRGKLSSSFSSRGQQQEP 1291
Score = 32.0 bits (71), Expect = 6.8
Identities = 17/60 (28%), Positives = 26/60 (43%)
Query: 233 KPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESE 292
K R + + S +S + S G D EE + EE++ E ++DDS E E
Sbjct: 1198 KQRSRRLSSRQRPSLESDEDVEDSMGGEDDEVDGDEEEGQSEEEEYEVEQDEDDSQEEEE 1257
Score = 31.6 bits (70), Expect = 8.8
Identities = 27/116 (23%), Positives = 61/116 (52%), Gaps = 19/116 (16%)
Query: 944 QEKIKRIQQIRME-KELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKH 1002
++ + ++Q + E +EL+A+Q +K++EEAA A++ ++ KE++++ Q+ + +
Sbjct: 635 EDYVDILRQAKQEFRELKAEQ----HRKEREEAA-ARI----RKRKEEKLKEQEQKMKEK 685
Query: 1003 QERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKE 1058
QE+ +K E R + ++E+ D + + EQ+ L+ +M E
Sbjct: 686 QEK---------LKEDEQRNSTADISIGEEEREDFDTSIESKDTEQKELDQDMVTE 732
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 106 bits (264), Expect = 3e-22
Identities = 112/600 (18%), Positives = 228/600 (38%), Gaps = 20/600 (3%)
Query: 144 AQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKST 203
+ + DS S +S S S+ + + S N S++S + S S+ +S S + S+
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780
Query: 204 SSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSS 263
+S N N S + + D + +S S++ SDS SSD+S SS
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 264 DSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEK 323
SD + + + S S+ +S S++ SN S +D + E +
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN--------SSDSSDSSDSNESSNSS 892
Query: 324 RIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSN 383
+ + S S S SS++ S N ++S ++ S+
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSS------DSSESSNSSDNSNSSDSSNSSDSSD 946
Query: 384 VKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLK 443
S + + + S D N + S +SS + S
Sbjct: 947 SSDSSNSSDSSNSSDSSNSSDSSD----SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 444 KQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQ 503
+SS S ++ S+ + SS ++ + +++ + ++ + +
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 504 EAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQG 563
+ + ++ + S +++ ++ S+ S+ + S S + + + +S S
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 564 KEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDD 623
+ S++ + + S+ + S SD S DS DS++ + D +
Sbjct: 1123 SSDS-SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1181
Query: 624 EDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESD-SDTEGEKTSMKLNKTTSSVKSP 682
+ +S DS SDS+ SD+ S + D D SD SD+ S N+++ S S
Sbjct: 1182 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSS 1241
Query: 683 SMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDE 742
S + +S+ + + ++ + S+SQS + G ++ + + S G+ +D+
Sbjct: 1242 DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 103 bits (256), Expect = 2e-21
Identities = 123/608 (20%), Positives = 225/608 (37%), Gaps = 20/608 (3%)
Query: 144 AQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKST 203
A++ DS S + SN NG NG+ + + S G + S S ++ SS S
Sbjct: 510 AEDDDSDSTSDTNNSDSNGNGN----NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 204 SSGG----GNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDS-DSGTSSDTSSE 258
SS N + + S + D+ D + +SS +SDS DS SSD+ S+
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 259 GISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATE 318
S S+SD + D + + S+ D+ S++ + SN+ + +
Sbjct: 626 S-SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 319 KAQEKRIHQPLPLASES--QTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQ 376
+ + +SES + S S S SS + + S + ++S
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 377 STGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQ 436
+ SN S + + + S D + N + S +SS + S
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 437 AFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNG 496
+SS S + SN +S S + ++ + +++ + N
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 497 VIQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSAS 556
S ++ + + S + N + +S + SS + S S + + + +S
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924
Query: 557 PILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDE 616
+S SN+ + + S + S SD +S DS DSN + D
Sbjct: 925 ESSNSSDN----SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSS 980
Query: 617 EEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTT 676
+ D D SD S S SNS ++ S+ D + + SD+ S + ++
Sbjct: 981 NSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 677 SSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKR 736
S S S + S+ + + + S+ ++ S+S + SS + SS S +S
Sbjct: 1041 DSSDSSDSSDSSDSS----NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096
Query: 737 RRVTDERE 744
+D +
Sbjct: 1097 SDSSDSSD 1104
Score = 102 bits (254), Expect = 4e-21
Identities = 117/601 (19%), Positives = 222/601 (36%), Gaps = 9/601 (1%)
Query: 146 NHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSS 205
N SS +S +S SN + + S + ++SS N+S S ++ SS S SS
Sbjct: 646 NSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 705
Query: 206 GGGNRKCNQ--EQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSS 263
+ + + S + D+ D + +SS +SDS + + S SS+ +SS
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765
Query: 264 DSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEK 323
DS D + + D S S+ +DS + S++ SN+ + SD + +
Sbjct: 766 DSSDSSDSSDSSDSS-NSSDSNDSSNSSDSSDSSNSSDSSNS-SDSSDSSDSSDSDSSNS 823
Query: 324 RIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSN 383
+S+S S S S SS + S + +S + S+
Sbjct: 824 SDSSNSSDSSDSSNSSDSSDSSDSSDGSDS-----DSSNRSDSSNSSDSSDSSDSSNSSD 878
Query: 384 VKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLK 443
S N++ + S D + + N+S+ S S S+ S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 444 KQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQ 503
S S + S+ +S S + N+ + +N+ + + S
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 504 EAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQG 563
++ + + S + N + +S++ SS + S+ + + S S +
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 564 KEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDD 623
S++ + + S + S S+ S DS DS++ + D + +
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 624 EDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPS 683
+ S DS SDS+ SD+ S + D + D SDS + + + +S S
Sbjct: 1119 DSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1178
Query: 684 MSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDER 743
S + + + + S+ ++ S+S + SS + SS S +S +D
Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSS 1238
Query: 744 E 744
+
Sbjct: 1239 D 1239
Score = 102 bits (253), Expect = 5e-21
Identities = 114/599 (19%), Positives = 231/599 (38%), Gaps = 10/599 (1%)
Query: 146 NHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSS 205
++ S S S S S+ N + + S++S ++S S ++ SS S SS
Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSS 617
Query: 206 GGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDS 265
+ K + +S++ D+ K + +SS NSDS ++S SS+ SSDS
Sbjct: 618 DSSDSKSDSSKSESDSSDS---DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDS 674
Query: 266 DDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRI 325
D + + S + S+ DS + SE+ S++ S ++ + +
Sbjct: 675 SDSSSSSDSSNSS-DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733
Query: 326 HQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVK 385
+S+S S S S SS + + S + +S + SN
Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS-DSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 386 PLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQ 445
S + + + S D + + N+S+ S+ +S+ + S
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN--SSDSSDSSNSSDSSDSSDSSDG 850
Query: 446 ESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEA 505
S S + ++ S+ + SS ++ + +++ N +N+ + N +
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES-SNSSDSSDSSNSSDSDSSDSS 909
Query: 506 PLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKE 565
+ ++ + S +E+ ++ ++ S N S S + + + ++S S +
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD--SSNSSD 967
Query: 566 KAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDED 625
+ SN+ + + + S + S SD +S DS DS++ + + + +
Sbjct: 968 SSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDS 1027
Query: 626 DESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMS 685
S DS SDS+ SD+ S + D D SDS + + + +S S S
Sbjct: 1028 SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDS 1087
Query: 686 LTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDERE 744
++ + + + S+ ++ S+S + SS + SS S +S +D +
Sbjct: 1088 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSD 1146
Score = 99.4 bits (246), Expect = 3e-20
Identities = 112/601 (18%), Positives = 226/601 (37%), Gaps = 5/601 (0%)
Query: 144 AQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKST 203
+ + DSS + KS+ + E + S + S++S ++S S ++ SS S
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667
Query: 204 SSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSS 263
SS + + S + D D ++ +SS +SDSDS SSD+S+ S S
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDS-SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 264 DSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEK 323
DS + D + S + S+ DS + S++ S++ + + + +
Sbjct: 727 DSSN-SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785
Query: 324 RIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSN 383
+S+S S S S +S S + S S S+
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 384 VKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLK 443
+ + + S D + N + S +SS ++E + + + S
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD-SNESSNSSDSSDSSNSSDSD 904
Query: 444 KQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQ 503
+SS S ++ S+ + SS+ + + ++++ + ++ N +
Sbjct: 905 SSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Query: 504 EAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQG 563
+ + + + N + ++ SS S + +S + + S++ S
Sbjct: 965 SSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNS 1024
Query: 564 KEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDD 623
+ SN+ + + S + S S+ S DS DS++ + D + +
Sbjct: 1025 SDS--SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082
Query: 624 EDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPS 683
E +S DS + SDS+ SD+ S + D D SDS + + + +S + S
Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 1142
Query: 684 MSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDER 743
S + + + + S+ ++ S+S + SS + SS S +S +D
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1202
Query: 744 E 744
+
Sbjct: 1203 D 1203
Score = 98.6 bits (244), Expect = 6e-20
Identities = 115/606 (18%), Positives = 230/606 (37%), Gaps = 22/606 (3%)
Query: 144 AQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTS-SVIGINTSVLSTTASSSMGQTKS 202
+ + DSS S S S+ + + S + S++S S + S ++ S S +
Sbjct: 585 SDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSD 644
Query: 203 TSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISS 262
++S + + S N + D + +SS++SDS + S SSE S
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 263 SDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQE 322
SDS D + + D S S D DS + S++ SN+ S +D +++ +
Sbjct: 705 SDSSD-SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD-----SSDSSDSSNSSDSSDS 758
Query: 323 KRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVS 382
+S+S S S S S +S + S S S
Sbjct: 759 SDSSN----SSDSSDSSDSSDSSDSSNSSDS-----NDSSNSSDSSDSSNSSDSSNSSDS 809
Query: 383 NVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQL 442
+ S + + + S D + + + S +SS + S R + S
Sbjct: 810 SDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS- 868
Query: 443 KKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVI 502
+SS S ++ SN + SS + + +++ + ++ + + +S
Sbjct: 869 DSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS- 927
Query: 503 QEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQ 562
+ + ++ + S +++ +++S+ S+ + S S + N + S++ S
Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSD 987
Query: 563 GKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDS----DIPSSKDSEDSNEDEEEDDEEE 618
+ + S++ + S + + +DS D +S DS DS++ + D +
Sbjct: 988 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSD 1047
Query: 619 DEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSS 678
+ + S DS SDS+ SD+ S + D + D SDS + + + +S
Sbjct: 1048 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD 1107
Query: 679 VKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRR 738
S S + + + + S+ ++ S S + SS + SS S +S
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSD 1167
Query: 739 VTDERE 744
+D +
Sbjct: 1168 SSDSSD 1173
Score = 98.2 bits (243), Expect = 8e-20
Identities = 112/598 (18%), Positives = 216/598 (36%), Gaps = 12/598 (2%)
Query: 149 SSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGG 208
S S S +S SN + + + SN+SS + S S ++ S + ++S
Sbjct: 547 SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606
Query: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTS--SEGISSSDSD 266
+ + + D++ D K + + S +SDS+S SSD S S+ +SS+S
Sbjct: 607 SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 267 DLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIH 326
D + + D S + SDS S++ SN+ +D +++ +
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDS-SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Query: 327 QPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKP 386
+S+S S S S SS + + S + +S + S+
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSS----DSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 387 LSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQE 446
S N + + S D + + + S +SS S S + S
Sbjct: 782 SSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 447 SSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAP 506
S S + + + SS + ++ + +++ N N S +
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS- 900
Query: 507 LALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEK 566
+ + N + ++ SS S + ++S + + S+ S +
Sbjct: 901 ----SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS 956
Query: 567 AVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDD 626
+ S++ + S+ + S SD S DS DS++ D + + +
Sbjct: 957 SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1016
Query: 627 ESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSL 686
S DS + SDS++ SD+ S + D D SDS + + +S S S
Sbjct: 1017 NSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSS 1076
Query: 687 TGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDERE 744
+ + + + S+ ++ S+S + SS + SS S +S +D +
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Score = 97.1 bits (240), Expect = 2e-19
Identities = 121/607 (19%), Positives = 233/607 (38%), Gaps = 38/607 (6%)
Query: 148 DSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGG 207
D S+ + + +S+ N +G + + + G ++ S S T ++ S G
Sbjct: 469 DESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNG 528
Query: 208 GNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDT-SSEGISSSDSD 266
N + K+ D K K + S S++ SDS SSD+ SS+ SSSDSD
Sbjct: 529 NGNNGNDDNDKS-------DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD 581
Query: 267 DLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIH 326
+ D S + S+ D SDS + + ++ S +D + + K++
Sbjct: 582 SSDSD------SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635
Query: 327 QPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKP 386
S S S S SS + + S + +S S+ SN
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSS-------NSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 387 LSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQE 446
S + + + S D + + ++S+ S+ +S+ S + +
Sbjct: 689 SSDSSDSSNSSESS---DSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 447 SSKSLKKVIAALSNPKATS-----SSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSV 501
SS S ++ S+ + S SS + N+ + +N+ + N S
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805
Query: 502 IQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPV---MPSASPI 558
++ + + S +++ ++ S+ S+ + S S + G+ + S++
Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS 865
Query: 559 LHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEE 618
S + + S++ + + S + + +DSD S +S DS++ D E
Sbjct: 866 DSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSE 925
Query: 619 DEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESD-SDTEGEKTSMKLNKTTS 677
++ S DS + SDS+ SD+ S + + + SD SD+ +S N + S
Sbjct: 926 SSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985
Query: 678 SVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRR 737
S S S + S N + S+ ++ S+S + + SS + SS S +S
Sbjct: 986 SDSSDSSDSSDSSDSSN-----SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS 1040
Query: 738 RVTDERE 744
+D +
Sbjct: 1041 DSSDSSD 1047
Score = 97.1 bits (240), Expect = 2e-19
Identities = 119/616 (19%), Positives = 232/616 (37%), Gaps = 25/616 (4%)
Query: 147 HDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMG-------- 198
+ S +S + G ++ N E NG NGS++ ++ S T +S
Sbjct: 478 NSESDNNSSSRGDASYNSDESKDNG--NGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND 535
Query: 199 -QTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDT-S 256
KS S G + + + S + D + S +SDSDS SSD+ S
Sbjct: 536 DNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDS 595
Query: 257 SEGISSSDSDDLEEDEEEEDQS-IEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQK 315
S+ +SSDS D + + D S +S+ D S SES++ + S +D
Sbjct: 596 SDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD 655
Query: 316 ATEKAQEKRIHQPLPLA-SESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSV 374
+++ + + S + S S S +SS + + S + +
Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS 715
Query: 375 IQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQY 434
S+ S+ S + + + S D + + + S +SS + S
Sbjct: 716 SDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Query: 435 KQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQP 494
+ +SS S ++ S+ + SS + + +++ N +++ +
Sbjct: 776 SSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNS--SDSSNSSDSS 833
Query: 495 NGVIQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPS 554
+ S ++ + S +++ ++ S+ S N S S + N++
Sbjct: 834 DSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Query: 555 ASPILHSQGKEKA-VSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEE 613
+S +S + + SN+ + + + S ++S SD +S DS DS++
Sbjct: 894 SSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953
Query: 614 DD--------EEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEG 665
D D D +S DS + SDS+ SD+ S + D D SDS
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 666 EKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTL 725
+ ++ + +S + S S + + + + S+ ++ S+S + SS +
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073
Query: 726 TSSPHSGTSKRRRVTD 741
SS S +S+ +D
Sbjct: 1074 DSSDSSDSSESSDSSD 1089
Score = 95.1 bits (235), Expect = 7e-19
Identities = 113/602 (18%), Positives = 216/602 (35%), Gaps = 13/602 (2%)
Query: 149 SSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGG 208
S+S +S S S+ + + S N S++S + S S+ +S S S SS
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Query: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDL 268
N + S N + D + SS +SDS ++S SS+ SSDS D
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Query: 269 EEDEEEEDQSIEESEDDDSDSE--SEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIH 326
+ D S D S+S S + S++ S +D +++ +
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSS 839
Query: 327 QPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKP 386
+ S S + S SS + + S + ++ ++ S+
Sbjct: 840 DSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSN 899
Query: 387 LSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQE 446
S + + S D + N + S ESS + S
Sbjct: 900 SSDSDSSDSSN-------SSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 447 SSKSLKKVIAALSNPKATS-SSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEA 505
SS S ++ S+ + S SS + ++ + +++ + N S ++
Sbjct: 953 SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Query: 506 PLALTTKTKMQSKINENIAAASSTPFSSPVNLST--SGRRTPGNQTPVMPSASPILHSQG 563
+ + S + N + +S + SS + S+ S N + S+ S
Sbjct: 1013 SDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1072
Query: 564 KEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDS-DIPSSKDSEDSNEDEEEDDEEEDEED 622
+ + S++ + S + + +DS D S DS DS++ D + +
Sbjct: 1073 SDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1132
Query: 623 DEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSP 682
+ +S +S SDS+ SD+ S + D D SDS + ++ + +S
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 683 SMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDE 742
S S + + + + S+ ++ S+S + S+ + SS S +S +D
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDS 1252
Query: 743 RE 744
+
Sbjct: 1253 SD 1254
Score = 94.7 bits (234), Expect = 9e-19
Identities = 110/585 (18%), Positives = 227/585 (38%), Gaps = 17/585 (2%)
Query: 158 GKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQS 217
GK N +KG +G I G G ++ S G S+ G + N +
Sbjct: 393 GKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSD--SNSDGY 450
Query: 218 KNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQ 277
+ D DK + ES+ N D++S + +++SS G +S +SD+ +++ D
Sbjct: 451 DSYDFD---DKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDS 507
Query: 278 SIEESEDDDSDSESEAQHKSNNQVLLHGISD-PKADGQKATEKAQEKRIHQPLPLASESQ 336
+ +EDDDSDS S+ + +N +G D K+D K + + + S
Sbjct: 508 --KGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 337 THSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKE 396
+ S S S + S + ++S + S+ S + +K +
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 397 TYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQESSKSLKKVIA 456
+ S K+ + +++ S S+ + S +SS S +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD--SSDSSDSSSSSDS 683
Query: 457 ALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQ 516
+ S+ + SS ++ ++ +++ + ++ + N + + ++ +
Sbjct: 684 SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDS 743
Query: 517 SKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEKAVSNNVNPVK 576
S +++ ++ S+ S N S S + + + ++S S SN+ +
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS-------SNSSDSSD 796
Query: 577 TQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESD 636
+ + S + S SD SS S+ SN + D + D D SD S S+S
Sbjct: 797 SSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSS 856
Query: 637 SNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLH 696
+ S+S + D + +S ++ ++S + + SS S S S ++ +
Sbjct: 857 NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSD 916
Query: 697 IAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTD 741
+ + S+ ++ S++ + + SS + SS S +S +D
Sbjct: 917 SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Score = 94.4 bits (233), Expect = 1e-18
Identities = 122/613 (19%), Positives = 233/613 (38%), Gaps = 54/613 (8%)
Query: 153 HSRTSGKSNRNG------PEKGVNGS-------INGSNTSSVIGINTSVLSTTASSSMGQ 199
HS T SN +G +K + G NG++ ++ N S AS + +
Sbjct: 438 HSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDE 497
Query: 200 TKSTSSGGGNRKCNQEQSKNQPLDARVDKI---------KDKKPRKKAMESSSNSDS-DS 249
+K +G ++ + S + D DK K SS+SDS DS
Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDS 557
Query: 250 GTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDP 309
SSD+S SSDSD + + + S + D SDS+S S++ SD
Sbjct: 558 SNSSDSSD----SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDS 613
Query: 310 KADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVN 369
+ K+ +S+S++ S S K S + + S N
Sbjct: 614 SDSSDSSDSKSD----------SSKSESDSSDSDSKSDS----------SDSNSSDSSDN 653
Query: 370 KHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRS 429
+S ++ S+ S + + + S D + N + S +SS + S
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713
Query: 430 KREQYKQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALL 489
+ S SS S ++ S+ + SS+ + + ++++ + +++
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD-SSDSSD 772
Query: 490 GNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQT 549
+ + S ++ + + S + N + +S + SS + S S + +
Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD- 831
Query: 550 PVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNE 609
S+ S + + S++ + + + S + S S+ S DS DSNE
Sbjct: 832 ----SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887
Query: 610 DEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEED-DDDKDQDESDSDTEGEKT 668
D + + D SD S S S+S + ++ SE + D+ + +S + ++ +
Sbjct: 888 SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS 947
Query: 669 SMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSS 728
S N + SS S S + + S + + + S+ ++ S+S + SS++ SS
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 729 PHSGTSKRRRVTD 741
S +S +D
Sbjct: 1008 DSSDSSDSSNSSD 1020
Score = 92.8 bits (229), Expect = 3e-18
Identities = 108/596 (18%), Positives = 219/596 (36%), Gaps = 13/596 (2%)
Query: 149 SSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGG 208
SSS S S S+ + + S + S++S ++S S + SS + S+ S
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDS 737
Query: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDL 268
+ + S + + D + +SS +SDS ++S S++ +SSDS D
Sbjct: 738 SNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDS 797
Query: 269 EEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQP 328
+ + S D SDS+S S+N S +D +++ +
Sbjct: 798 SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSN-------SSDSSDSSNSSDSSDSSDSSDG 850
Query: 329 LPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLS 388
S +++ S S S SS + E S N S S S+ S
Sbjct: 851 SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS-NSSDSSDSSNSSDSDSSDSS 909
Query: 389 LVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQESS 448
N + S + N N+S+ S+ +S+ + + S +S
Sbjct: 910 --NSSDSSDSSNSSDSSESSNSSDNSNSSDSSN--SSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 449 KSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAPLA 508
++ S+ + SS + + +++ + ++ + + + + +
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025
Query: 509 LTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEKAV 568
++ + S +++ ++ S+ S + S S + + + +S S ++
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSES- 1084
Query: 569 SNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDES 628
S++ + + S + S SD S DS +S++ + D + + +S
Sbjct: 1085 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 1144
Query: 629 DDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTG 688
DS SDS+ SD+ S + D D SDS + + + +S S S
Sbjct: 1145 SDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204
Query: 689 HSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDERE 744
+ + + + S+ ++ S+S SS + SS S +S +D +
Sbjct: 1205 SDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260
Score = 82.0 bits (201), Expect = 6e-15
Identities = 102/551 (18%), Positives = 206/551 (37%), Gaps = 14/551 (2%)
Query: 202 STSSGGGNRKCNQEQSKNQPLDARVDKIKDK-KPRKKAMESSSNSDSDSGTSSDTS---S 257
S+ GN N E N D+ K +S D DS ++SDT+ S
Sbjct: 467 SSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDS 526
Query: 258 EGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKAT 317
G ++ +DD D+ + + +S D DS S + S++ S+ +D +
Sbjct: 527 NGNGNNGNDD--NDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSD 584
Query: 318 EKAQEKRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQS 377
+ + +S+S S S S S + + + S +S
Sbjct: 585 SDSSDSSDSD----SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640
Query: 378 TGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLL--TSELRSKREQYK 435
SN S + + + S D + + ++S +SS +S+ +
Sbjct: 641 DSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSE 700
Query: 436 QAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPN 495
+ S +SS S + S+ +++SS + ++ + +N+ + +
Sbjct: 701 SSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 760
Query: 496 GVIQSVIQE-APLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPS 554
S + + + ++ + S N++ ++ S+ S+ + S S + + + S
Sbjct: 761 SSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDS 820
Query: 555 ASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEED 614
++ S + + S+N + S R S+ S DS DS+ +
Sbjct: 821 SNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
Query: 615 DEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEED-DDDKDQDESDSDTEGEKTSMKLN 673
D + E +S DS + SDS+S + S+ D + D ES + ++ +S N
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 674 KTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGT 733
+ SS S S + + S + + + ++ S+S + + SS + SS S +
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 734 SKRRRVTDERE 744
S +D +
Sbjct: 1001 SNSSDSSDSSD 1011
Score = 68.9 bits (167), Expect = 5e-11
Identities = 125/634 (19%), Positives = 223/634 (35%), Gaps = 81/634 (12%)
Query: 157 SGKSNRNGPEKGVNGSINGSNTSSVI--------GINTSVLSTTASSSMGQTKSTSSGGG 208
S S N E N N NTS + G + ++ G S S G
Sbjct: 189 SNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSG 248
Query: 209 NRKCNQE-QSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDD 267
N E + D KD K E D G D S +SDS +
Sbjct: 249 NGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQ-----DHGKEDDHDSSIGQNSDSKE 303
Query: 268 LEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQE----- 322
+ E +ED E D S SE + GI P+ +G + E Q+
Sbjct: 304 YYDPEGKEDPHNEVDGDKTSKSEENSA----------GI--PEDNGSQRIEDTQKLNHRE 351
Query: 323 -KRIHQPLPLASESQTHSFQSQQ------KQPQVLSQQLPFIFQSSQAKEESVNKHTSVI 375
KR+ + ES+TH+ Q K P ++ + +E +H ++
Sbjct: 352 SKRVEN--RITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMIL 409
Query: 376 QSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEES-------------SL 422
+ + + +++ +K S K G+ NT +S S+
Sbjct: 410 GKGNVKTQGEVVNIEGPGQK---------SEPGNKVGHSNTGSDSNSDGYDSYDFDDKSM 460
Query: 423 LTSELRSKREQYKQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPNP 482
+ S E + + S + A+ ++ ++ + + E++ +
Sbjct: 461 QGDDPNSSDESNGN---DDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD- 516
Query: 483 FLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQS-------KINENIAAASSTPFSSPV 535
+ + N NG + + + + K K S N + ++ SS SS
Sbjct: 517 --STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDS 574
Query: 536 NLSTSGRRTPGNQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTD 595
N S+ + + + S S S + + S++ + S +KS +
Sbjct: 575 NSSSDSDSSDSDSSDSSDSDSSD-SSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633
Query: 596 SDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESD--DSQSESDSNSESDTEG---SEEED 650
SD S DS DSN + D+ + + + + SD DS SDS+S SD+ S +
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSS 693
Query: 651 DDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCS 710
D + SDS + S + +++S S S S + + + + + S+ ++ S
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSS 753
Query: 711 ESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDERE 744
+S + SS + SS S +S +D +
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND 787
Score = 34.7 bits (78), Expect = 1.0
Identities = 15/49 (30%), Positives = 18/49 (36%)
Query: 1295 GDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
G SD D D DS + D D + D D D D D + S
Sbjct: 545 GKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593
Score = 33.9 bits (76), Expect = 1.8
Identities = 16/63 (25%), Positives = 23/63 (36%)
Query: 1297 SDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSK 1356
SD D D DS+ D D D + + +D D D + S + + SK
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 1357 QQS 1359
S
Sbjct: 624 SDS 626
Score = 33.1 bits (74), Expect = 3.0
Identities = 49/264 (18%), Positives = 89/264 (33%), Gaps = 18/264 (6%)
Query: 1289 KRRRKGGDSDYDDDDDDDS-------DDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQA 1341
K G DS +DDD DS D G+ ++ ++++ + GK D D D +
Sbjct: 499 KDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSS 558
Query: 1342 ASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQDRYRRRYWILPQCGGIFVEGME 1401
S + + S S D+ S S D + +
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSD 618
Query: 1402 SGEGLEEIAKEREKLKKAESVQIKEEMFET-------SGDSLNCSN----TDHCEQKEDL 1450
S + + +K ++S + + S DS N SN +D + +
Sbjct: 619 SSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSS 678
Query: 1451 KEKDNTNLFLQKPGSFSKLSKLLEVAKMPPESEVMTPKPNAGANGCTLSYQNSGKHSLGS 1510
D++N S S S + +S+ ++ +N NS S S
Sbjct: 679 SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSS 738
Query: 1511 VQSTATQSNVEKADSNNLFNTGSS 1534
S ++ S+ S++ ++ SS
Sbjct: 739 NSSDSSDSSDSSNSSDSSDSSDSS 762
Score = 33.1 bits (74), Expect = 3.0
Identities = 26/114 (22%), Positives = 37/114 (32%), Gaps = 10/114 (8%)
Query: 1263 TGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKE 1322
T D++G + G + + G K SD D D +S D D D D D
Sbjct: 521 TNNSDSNGNGNNGNDDNDKSDSGKG-----KSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575
Query: 1323 -----DKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHS 1371
D + D D D + S + + S S D+S S
Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS 629
Score = 32.3 bits (72), Expect = 5.2
Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 9/81 (11%)
Query: 1285 TPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDE----DEEDKEDKKGKKTDICEDEDEGDQ 1340
TPG G D+ D+ D S + DED++ D+ED+E GK + EG
Sbjct: 230 TPGT-----GEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQD 284
Query: 1341 AASVEELEKQIEKLSKQQSQY 1361
++ + I + S + Y
Sbjct: 285 HGKEDDHDSSIGQNSDSKEYY 305
>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
sapiens]
Length = 1110
Score = 100 bits (248), Expect = 2e-20
Identities = 69/236 (29%), Positives = 99/236 (41%), Gaps = 63/236 (26%)
Query: 1933 YCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKL 1992
+C +C+ G + LL C+ C K H CH P + + P GDW C C + + ++
Sbjct: 889 WCAVCQNGGD---LLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFC------RDIGKPEV 939
Query: 1993 HVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESF 2052
SKKGK +G + +RK
Sbjct: 940 EYDCDNLQHSKKGKTA-------------------QGLSPVDQRK--------------- 965
Query: 2053 TSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIRE 2112
C +L + HE + F PV +P Y K+IKKPMD ST+++
Sbjct: 966 ----------------CERLLLYLYCHELSIEFQEPVPAS-IPNYYKIIKKPMDLSTVKK 1008
Query: 2113 KLS---SGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKWTDTF 2165
KL S Y + F DVRL+F NCE FNE DS++ +AG + YFE K T+ +
Sbjct: 1009 KLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGKAVALYFEDKLTEIY 1064
>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
[Homo sapiens]
Length = 1050
Score = 97.1 bits (240), Expect = 2e-19
Identities = 69/232 (29%), Positives = 94/232 (40%), Gaps = 65/232 (28%)
Query: 1933 YCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKL 1992
+C +C+ G LL C+ C K H CH P +T P G+W C C
Sbjct: 828 WCAVCQNGGE---LLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFC-------------- 870
Query: 1993 HVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKME---ENTSINLSKQ 2049
+DL K ++E + S N K+
Sbjct: 871 --------------------------------------RDLSKPEVEYDCDAPSHNSEKK 892
Query: 2050 ESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFST 2109
++ VK D K C +L + HE + F PV L VP Y K+IK PMD ST
Sbjct: 893 KTEGLVKLTPIDKRK----CERLLLFLYCHEMSLAFQDPVPLT-VPDYYKIIKNPMDLST 947
Query: 2110 IREKLSS--GQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEK 2159
I+++L Y E F D RL+F NC FNE DS++ AG + YFE+
Sbjct: 948 IKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEE 999
>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
[Homo sapiens]
Length = 1016
Score = 97.1 bits (240), Expect = 2e-19
Identities = 69/232 (29%), Positives = 94/232 (40%), Gaps = 65/232 (28%)
Query: 1933 YCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKL 1992
+C +C+ G LL C+ C K H CH P +T P G+W C C
Sbjct: 794 WCAVCQNGGE---LLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFC-------------- 836
Query: 1993 HVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKME---ENTSINLSKQ 2049
+DL K ++E + S N K+
Sbjct: 837 --------------------------------------RDLSKPEVEYDCDAPSHNSEKK 858
Query: 2050 ESFTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFST 2109
++ VK D K C +L + HE + F PV L VP Y K+IK PMD ST
Sbjct: 859 KTEGLVKLTPIDKRK----CERLLLFLYCHEMSLAFQDPVPLT-VPDYYKIIKNPMDLST 913
Query: 2110 IREKLSS--GQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEK 2159
I+++L Y E F D RL+F NC FNE DS++ AG + YFE+
Sbjct: 914 IKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEE 965
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 90.9 bits (224), Expect = 1e-17
Identities = 101/509 (19%), Positives = 222/509 (43%), Gaps = 88/509 (17%)
Query: 590 QFRGTDSDIPSSKDSEDS--NEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSE 647
Q G D + + D ++S + +E+D+ E D E + Q E + E +E
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Query: 648 EEDDDDK-------DQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAKA 700
E+ +K D+ D + ++ + + + + S GH T
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET--------- 201
Query: 701 PGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDERELRI---PLEYGWQ-RE 756
+ P L G ++++ ER+ R+ E W+ RE
Sbjct: 202 -----------EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRE 250
Query: 757 TRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVGDFYE 816
T +R +LQ E ++L++ E ++ L R + ++ ++R
Sbjct: 251 TVLRKEEEKLQEEEPQRQ---RELQEEEEQLRKLERQELRRERQEEEQQQQRLR------ 301
Query: 817 ARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAE 876
+ Q +EE+ R E RR + ++Q R E ++RR +
Sbjct: 302 -----REQQLRRKQEEE---RREQQEERREQQERREQQEERREQQLRREQE--------- 344
Query: 877 FLDNADAKLLRKLQA----QEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKR 932
+ + +L R+ + Q++ R+ + + ++L++++Q R ++ +++Q + ++ R
Sbjct: 345 --ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402
Query: 933 KQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIK---- 988
++++ ++++++++R QQ+R E++LR +Q E ++K E+ + L+ E+ +
Sbjct: 403 REQQ----LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458
Query: 989 ---------EKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKE---RLKQEKRD 1036
E+E R+QQ LK + E RR+ + ++ E R++ E +E R +QE+R
Sbjct: 459 KREEETERHEQERRKQQ---LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 1037 EKRLNKERKLEQRRLELEMAKELKKPNED 1065
E+RL ++ + E+ + L ++L++ E+
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEE 544
Score = 89.4 bits (220), Expect = 4e-17
Identities = 59/237 (24%), Positives = 127/237 (53%), Gaps = 8/237 (3%)
Query: 839 RAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQA 898
R + RR + Q+ +E R +R K + + + ++ + Q++ R
Sbjct: 421 REQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Query: 899 AQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQ---KEQIKIMKQQEKIKRIQQIRM 955
+ + R L+ +E+ R ++ +++Q + +E+R++ K Q + + Q++++ QQ+R
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 956 EKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLM 1015
E+E R +Q+L+ +++K+ E E+R+K ++ R+ +L + +ER ++R
Sbjct: 541 EQEERREQLLKREEEKRLEQERR-----EQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 1016 KAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQK 1072
+ +E R K EE ERL+QE+R E+RL +E E+RR +L ++E ++ + +Q+
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Score = 83.6 bits (205), Expect = 2e-15
Identities = 61/234 (26%), Positives = 129/234 (55%), Gaps = 32/234 (13%)
Query: 825 QWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAK 884
+W L+EE+ R + R Q R E R++R++ + +
Sbjct: 487 RWLKLEEEE-----RREQQERREQQLRREQEERREQRLKRQE--------------EEER 527
Query: 885 LLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQ 944
L ++L++++ R+ + + + L+++E+ R+ +E ++Q+ EE+R Q + + ++Q
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587
Query: 945 EKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQE 1004
+++KR Q+ R+E+ L+ +++ +++++ E + KR + +E RRQQ LLK +E
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERRE-------QRLKREEPEEERRQQ--LLKSEE 638
Query: 1005 RERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKE 1058
+E RRQ + + E R++ ++E ++E+R E+RL +E E+ R E E+A+E
Sbjct: 639 QEERRQQQLRREQQERREQRLKRE--EEEERLEQRLKREH--EEERREQELAEE 688
Score = 83.6 bits (205), Expect = 2e-15
Identities = 53/182 (29%), Positives = 110/182 (60%), Gaps = 10/182 (5%)
Query: 892 QEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKR-KQKEQIKIMKQQEKIKRI 950
Q + RQ + +L ++L+ ++Q R +E +++Q + EEKR +Q+ + + +K++++ +R
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 951 QQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQ 1010
Q ++ E+E R Q++ K+++EE +L E E+E RR+Q L + + E RRQ
Sbjct: 577 QLLKREEERRQQRL----KREQEERLEQRLKREEVERLEQEERREQR-LKREEPEEERRQ 631
Query: 1011 HMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLAD 1070
L+K+ E ++ +++ R +Q++R E+RL +E E+ RLE + +E ++ + LA+
Sbjct: 632 --QLLKSEEQEERRQQQLRREQQERREQRLKREE--EEERLEQRLKREHEEERREQELAE 687
Query: 1071 QK 1072
++
Sbjct: 688 EE 689
Score = 75.5 bits (184), Expect = 5e-13
Identities = 64/231 (27%), Positives = 118/231 (51%), Gaps = 29/231 (12%)
Query: 852 DRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLR----KLQAQEIARQAAQIKLLRKL 907
+ + REE RRR+ + E L + +LLR K + QE RQ + K KL
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDK---KL 966
Query: 908 QKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEA 967
Q++E+ + +E +K++ E ++K +E+ ++ +++E++ +R E+E R +Q E
Sbjct: 967 QQKEEQLLGEEPEKRRR---QEREKKYREEEELQQEEEQL-----LREEREKRRRQEWER 1018
Query: 968 KKKKK------------EEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERE-RRRQHMML 1014
+ +KK EE +L E E++ +E+E +Q+ L +ERE RRRQ +
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELER 1078
Query: 1015 MKAMEARKKAEEKERLKQEKRDEKRLNKERKL-EQRRLELEMAKELKKPNE 1064
E + EE++ L++E +R +ER+ E+ L+ E + L++ E
Sbjct: 1079 QYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE 1129
Score = 71.2 bits (173), Expect = 1e-11
Identities = 53/245 (21%), Positives = 131/245 (53%), Gaps = 24/245 (9%)
Query: 841 MEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQ 900
+E ++ R +R+ +E ++RR++G+ + D +LL++ + Q++ RQ
Sbjct: 1583 LEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERD 1642
Query: 901 IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRM----E 956
K L +E+ ++ ++ ++QQ + K +++EQ+ ++++++R ++ R E
Sbjct: 1643 RKFL-----EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEE 1697
Query: 957 KELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMK 1016
++LR Q E ++K +E + E E++ +E+E RQ+ + ++ R+ ++ +++
Sbjct: 1698 QQLRRQ---ERERKFLQEEQQLRRQELERKFREEEQLRQET---EQEQLRRQERYRKILE 1751
Query: 1017 AMEARKKAEEKERLKQEK----RDEKRLNKERKLEQRRLE-----LEMAKELKKPNEDMC 1067
+ R + EE++ +QE+ R+E++L +ER+ +Q R + ++L++ E+
Sbjct: 1752 EEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Query: 1068 LADQK 1072
L Q+
Sbjct: 1812 LRPQQ 1816
Score = 70.1 bits (170), Expect = 2e-11
Identities = 57/257 (22%), Positives = 119/257 (46%), Gaps = 22/257 (8%)
Query: 825 QWCLLKEED-----VIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLD 879
QW L E D V R R EG+R R +++R RE + + R E
Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Query: 880 NADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIK 939
+ + E RQ + + Q++ Q R + +++Q + EE+++Q+ +
Sbjct: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRR-- 822
Query: 940 IMKQQEKIKRIQQIRMEKEL----RAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995
+++E+ K +Q + E++L RAQQ+ E + +E+ ++R + +E RR
Sbjct: 823 --QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQED---------QERRRSQEQRRD 871
Query: 996 QAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEM 1055
Q + +E +RR+H + K + +E++ L++E+ + +R +E++ Q +
Sbjct: 872 QKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYR 931
Query: 1056 AKELKKPNEDMCLADQK 1072
+E + E+ L +++
Sbjct: 932 EEEQLQQEEEQLLREER 948
Score = 70.1 bits (170), Expect = 2e-11
Identities = 59/233 (25%), Positives = 126/233 (54%), Gaps = 25/233 (10%)
Query: 852 DRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRK--LQK 909
+ Q EE RRR+ R E L + +LLR+ + ++ RQ + + +K LQ+
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLRE-EREKRRRQEWERQYRKKDELQQ 1028
Query: 910 QEQARVAKEAKK----QQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQIL 965
+E+ + +E +K ++ EE+ Q+E+ +++ ++ + +R Q++ E++ R ++ L
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL--ERQYRKEEEL 1086
Query: 966 EAKKKK--KEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKK 1023
+ ++++ +EE + E E++ +E+E +Q+ L +ERE+RR+ E ++
Sbjct: 1087 QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR-------QELERQ 1139
Query: 1024 AEEKERLKQEKRDEKRLNKERKLEQRRLELEM----AKELKKPNEDMCLADQK 1072
E+E ++QE E++L +E ++RR ELE +EL++ E + +Q+
Sbjct: 1140 YREEEEVQQE---EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQE 1189
Score = 68.2 bits (165), Expect = 9e-11
Identities = 166/886 (18%), Positives = 342/886 (38%), Gaps = 95/886 (10%)
Query: 214 QEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEE 273
++Q + + + R ++ +++ R++ ++ D + + L+ D+E
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481
Query: 274 EEDQS----IEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPL 329
EE + +EE E + E Q + + + Q+ + +E+R+ Q L
Sbjct: 482 EERRERWLKLEEEERREQQERREQQLRREQE---------ERREQRLKRQEEEERLQQRL 532
Query: 330 PLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSL 389
SE Q Q ++++ + ++ + Q + +E+ + + + L +
Sbjct: 533 --RSEQQLRREQEERREQLLKREEEKRLEQ--ERREQRLKREQEERRDQLLKREEERRQQ 588
Query: 390 VNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQESSK 449
+ ++E ++ + +V + + E+ R KRE+ ++ QL K E +
Sbjct: 589 RLKREQEERLEQRLKREEVERLEQEERREQ--------RLKREEPEEERRQQLLKSEEQE 640
Query: 450 SLKKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAPLAL 509
++ + +Q L+ L L H+ Q + +E
Sbjct: 641 ERRQ-------QQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 510 TTKTKM-----QSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGK 564
+ K Q ++ A S +S P G+R Q L Q +
Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRP--RKQEGQRRRQEQEEKRRRRESELQWQEE 751
Query: 565 EKAVSNNVNPVKTQHHSHPAKSLVEQFRGTD--SDIPSSKDSEDSNEDEEEDDEEE---- 618
E+A + + + ++ + RG S P ++ + EE + E
Sbjct: 752 ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFL 811
Query: 619 -DEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTS 677
+EE+ E + E + + E + + + Q+E D E ++ +
Sbjct: 812 PEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD 871
Query: 678 SVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRR 737
+ R H A + L E Q L L KRR
Sbjct: 872 QKWRWQLE---EERKRRRHTLYAKPALQEQLRKEQQ---LLQEEEEELQREERE---KRR 922
Query: 738 RVTDERELRIPLEYGWQRETRIRNFGG--RLQGEVAYYAPCGKKLRQYPEVIKYLSRNGI 795
R ER+ R + + E +R R Q Y KKL+Q E + G
Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK-DKKLQQKEEQLL-----GE 976
Query: 796 MDISRDNFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEG---RRGRPPNPD 852
R K Y + Q + LL+EE R + E ++ +
Sbjct: 977 EPEKRRRQEREKK------YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE 1030
Query: 853 RQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQ 912
Q REE RR + R E L + +LL + +E R+ +L R+ +K+E+
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLG--EERETRRRQ---ELERQYRKEEE 1085
Query: 913 ARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQ--IRMEKELRAQQILEAKKK 970
+ +++Q + EKR+++E+ + +++E++++ ++ +R E+E R +Q LE + +
Sbjct: 1086 L----QQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 971 KKEEAANAKLLEAEKRIKEK-EMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKER 1029
++EE E E+ ++E+ E RR+Q + +++E E +Q + E K+ +E+ER
Sbjct: 1142 EEEEVQQ----EEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 1030 LKQEKRDEKRLNKERKLEQRRLELEMAKELK---KPNEDMCLADQK 1072
+ R+E+ L ++++ +QR + + +LK +P ++ + D K
Sbjct: 1198 ---QYREEEELQRQKR-KQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Score = 67.8 bits (164), Expect = 1e-10
Identities = 55/248 (22%), Positives = 124/248 (50%), Gaps = 9/248 (3%)
Query: 837 RIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIAR 896
R R + R P+R+ EE ++ R++ + + + L + R+ R
Sbjct: 1499 RDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFR 1558
Query: 897 QAAQIKLLRKLQK-QEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRM 955
+ Q++ R+ Q+ Q R K ++Q + E++RK E + +++QE ++++Q R
Sbjct: 1559 EEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD 1618
Query: 956 EKELRAQQILEAKKKKK--EEAANAKLLEAEKRIKEKEMRRQQAVLLKH-QERERRRQHM 1012
K +Q+L+ +++++ + + K LE E +++ +E +Q L+H ++R+ R +
Sbjct: 1619 RKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQ----LRHDRDRKFREEEQ 1674
Query: 1013 MLMKAMEARKKAEEKER-LKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQ 1071
+L + E + + +E++R ++E++ +R +ERK Q +L + +K E+ L +
Sbjct: 1675 LLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQE 1734
Query: 1072 KPLPELPR 1079
+L R
Sbjct: 1735 TEQEQLRR 1742
Score = 67.0 bits (162), Expect = 2e-10
Identities = 69/290 (23%), Positives = 138/290 (47%), Gaps = 48/290 (16%)
Query: 828 LLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRR----RKGRPPNVGNAE----FLD 879
LL+EE R R R+ R Q REE +RR RK R + + E FL+
Sbjct: 1320 LLREEREEKRRRQETDRKFREEEQLLQE-REEQPLRRQERDRKFREEELRHQEQGRKFLE 1378
Query: 880 NADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIK 939
+ +L R+ + ++ ++ Q++ + Q+ Q R K +++Q + E RK +E+ +
Sbjct: 1379 E-EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 940 IMKQQEKIKRI----QQIRMEKELR---AQQILEAKKKKK-----------EEAANAKLL 981
+++QE+ ++ QQ+R E+ + +Q+L+ +++++ EE +
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497
Query: 982 EAEKRIKEKEMRRQ--------QAVLLKHQERER---------RRQHMMLMKAMEARKKA 1024
E +++ +E+E+R Q + L Q+R+R RRQ + + +K
Sbjct: 1498 ERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKF 1557
Query: 1025 EEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPL 1074
E+E+L+QE+ +++ +ER R+ LE K ++ E + D++ L
Sbjct: 1558 REEEQLRQEREEQQLSRQER---DRKFRLEEQKVRRQEQERKFMEDEQQL 1604
Score = 65.1 bits (157), Expect = 7e-10
Identities = 61/259 (23%), Positives = 127/259 (49%), Gaps = 28/259 (10%)
Query: 828 LLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRP-------PNVGNAE---- 876
LL+EE R E R + QR + + R R R P NA
Sbjct: 1183 LLREEQ---EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Query: 877 -FLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQK 935
+ + + R+L+ ++ + +Q L L +Q++ +E ++ Q + ++
Sbjct: 1240 VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQ---RDRHFPEE 1296
Query: 936 EQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995
EQ++ +Q+E +R ++ + EK+L + E ++K++ + + K E E+ ++E+E +
Sbjct: 1297 EQLEREEQKEAKRRDRKSQEEKQLLRE---EREEKRRRQETDRKFREEEQLLQEREEQP- 1352
Query: 996 QAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKL--EQRRLEL 1053
L+ QER+R+ + L + RK EE++RL++++R+ K L +E++L ++R +L
Sbjct: 1353 ----LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQL 1408
Query: 1054 EMAKELKKPNEDMCLADQK 1072
++ K E+ L+ Q+
Sbjct: 1409 RQDRDRKFREEEQQLSRQE 1427
Score = 65.1 bits (157), Expect = 7e-10
Identities = 55/227 (24%), Positives = 117/227 (51%), Gaps = 24/227 (10%)
Query: 842 EGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQI 901
E ++ R DR+ EE ++RR++ +FL ++L+ QE+ R+ +
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERE------RKFLQEE-----QQLRRQELERKFREE 1728
Query: 902 KLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQE--KIKRIQQIRMEKEL 959
+ LR+ +QEQ R + +K I+ E+ R ++E+ ++ +Q+ K + +Q+R E+E
Sbjct: 1729 EQLRQETEQEQLRRQERYRK---ILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE 1785
Query: 960 RAQQILEAKKK-KKEEAANAKLLEAEKRIKEKEMR---RQQAVLLKHQER----ERRRQH 1011
+ + E+ +K ++EE + E + R ++++ + ++ + L+ QE+ ER RQ+
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY 1845
Query: 1012 MMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKE 1058
+ K E++ L QE+ ++R +ERKL + + + +E
Sbjct: 1846 RAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE 1892
Score = 63.5 bits (153), Expect = 2e-09
Identities = 46/219 (21%), Positives = 121/219 (55%), Gaps = 23/219 (10%)
Query: 852 DRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQE 911
DR+ EE ++RR++ + + + +LL++ + Q++ RQ RK +++E
Sbjct: 1642 DRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD----RKFREEE 1697
Query: 912 QARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKK 971
Q ++ ++ ++++ + ++ R+Q+ + K ++++ + +Q ++ ++ R ++ILE ++ +
Sbjct: 1698 Q-QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 972 KE-EAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERL 1030
E E + E +++ +E+E R QERE ++ +++ E+ +K E+E+L
Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLR--------QEREEQQ-----LRSQESDRKFREEEQL 1803
Query: 1031 KQEKRDEKRLNKER----KLEQRRLELEMAKELKKPNED 1065
+QE+ +++ ++R + E+ +L+LE ++ + D
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERD 1842
Score = 62.0 bits (149), Expect = 6e-09
Identities = 66/296 (22%), Positives = 143/296 (48%), Gaps = 40/296 (13%)
Query: 816 EARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRARE-ESRMRRRKGRPPNVGN 874
E R QG ++ L+EE R+R E R + R +E E ++R+ + R
Sbjct: 1366 ELRHQEQGRKF--LEEEQ---RLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 875 AEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKR-- 932
+ + R+ + Q++ RQ + K L + Q+ Q R K +++Q + EE++
Sbjct: 1421 QQLSRQERDRKFRE-EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLH 1479
Query: 933 KQKEQIKIMKQQEKIKRIQQIRM--EKELRAQQ---------------------ILEAKK 969
+Q+ K ++++++++R ++ R E+ELR+Q+ + E ++
Sbjct: 1480 RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ 1539
Query: 970 KKKEEAANAKLLEAEKRIKEKEMRRQQAV--LLKHQERER--RRQHMMLMKAMEARKKAE 1025
+++E + + +++ +E+E RQ+ L QER+R R + + + + RK E
Sbjct: 1540 LRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME 1599
Query: 1026 EKERLK-QEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPELPRI 1080
++++L+ QE + + R ++RK + L+ +E + ++ D+K L E P++
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE---RDRKFLEEEPQL 1652
Score = 59.7 bits (143), Expect = 3e-08
Identities = 61/265 (23%), Positives = 131/265 (49%), Gaps = 28/265 (10%)
Query: 818 RDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPN----PDRQRAREESRMRRRKGRPPNVG 873
R Q +Q L ++++ R R E RR + + + Q REE + +R+ R
Sbjct: 1261 RQSQQDLQHLLGEQQE---RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRK---- 1313
Query: 874 NAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRK 933
+ +LLR+ + ++ RQ K + Q ++ ++++ EE+ +
Sbjct: 1314 -----SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELR 1368
Query: 934 QKEQ-IKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKE--EAANAKLLEAEKRIKEK 990
+EQ K ++++++++R Q R K L+ +Q L ++++++ + + K E E+++ +
Sbjct: 1369 HQEQGRKFLEEEQRLRR--QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQ 1426
Query: 991 EMR---RQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLE 1047
E R++ ++ QERER+ E +K E+E+L QE R+E++L+++ E
Sbjct: 1427 ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE-REEQQLHRQ---E 1482
Query: 1048 QRRLELEMAKELKKPNEDMCLADQK 1072
+ R LE ++L++ D +Q+
Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQE 1507
Score = 58.9 bits (141), Expect = 5e-08
Identities = 48/222 (21%), Positives = 117/222 (52%), Gaps = 13/222 (5%)
Query: 853 RQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLL---RKLQK 909
R+ +EE ++RR++ + + + +L ++ + Q+++RQ K +K+++
Sbjct: 1531 RKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590
Query: 910 QEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKK 969
QEQ R E ++Q +++ +Q+ K + ++ ++ ++ ++ ++ R ++ LE +
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 970 KKKEEAANAKLL-EAEKRIKEKEMRRQQAV--LLKHQERER--RRQHMMLMKAMEARKKA 1024
+ + + +L + +++ +E+E Q+ L+ QER+R R + L + RK
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710
Query: 1025 EEKERL-KQEK----RDEKRLNKERKLEQRRLELEMAKELKK 1061
+E+++L +QE R+E++L +E + EQ R + K L++
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE 1752
Score = 57.0 bits (136), Expect = 2e-07
Identities = 64/266 (24%), Positives = 131/266 (49%), Gaps = 45/266 (16%)
Query: 852 DRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLR----KLQAQEIARQ--------AA 899
+ Q REE RRR+ R E L + +LLR K + QE+ RQ
Sbjct: 1090 EEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149
Query: 900 QIKLLR----KLQKQEQARVAKEAKK-----QQAIMAAEEKRKQKEQIKIMKQQE--KIK 948
+ +LLR K ++QE R +E ++ +Q + +EKR+Q+ + + +++E + K
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Query: 949 RIQQIRME---KELRAQQILEAKKKKKEEAANAKLLEAE--KRIKEKEMRRQQA------ 997
R Q+ R E +L+ Q E + ++ K E E +++++ ++R +Q+
Sbjct: 1210 RKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH 1269
Query: 998 VLLKHQERER---------RRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQ 1048
+L + QER+R R +H + +E ++ E K R ++ + +++ L +ER+ ++
Sbjct: 1270 LLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKR 1329
Query: 1049 RRLELEMAKELKKPNEDMCLADQKPL 1074
RR E + ++ ++ + + +++PL
Sbjct: 1330 RRQETD--RKFREEEQLLQEREEQPL 1353
Score = 56.6 bits (135), Expect = 3e-07
Identities = 60/280 (21%), Positives = 131/280 (46%), Gaps = 43/280 (15%)
Query: 822 QGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRA-REESRMRRRKGRPPNVGNAEFLDN 880
Q Q L+EE + R RG+ DR R REE ++R+ + + L
Sbjct: 1527 QQRQRKFLQEEQQLRR-----QERGQQRRQDRDRKFREEEQLRQER-------EEQQLSR 1574
Query: 881 ADAKLLRKLQAQEIARQAAQIKL------LRKLQKQEQARVAKEAK-----------KQQ 923
+ +L+ Q++ RQ + K LR+ + Q+Q R ++ K ++Q
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 924 AIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKK--KEEAANAKLL 981
+ E RK E+ +++QE+ ++++ R K +Q+L+ +++ + + + K
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 982 EAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEK----RDE 1037
E E++++ +E R++ L + Q+ R+ + + R++ E+++ +QE+ +E
Sbjct: 1695 EEEQQLRRQE--RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE 1752
Query: 1038 KRLNKERKLEQRRLE-----LEMAKELKKPNEDMCLADQK 1072
++L ER+ +Q R + ++L++ E+ L Q+
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE 1792
Score = 44.7 bits (104), Expect = 0.001
Identities = 47/221 (21%), Positives = 109/221 (49%), Gaps = 39/221 (17%)
Query: 829 LKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRK 888
L++E ++R E R + REE ++RR++ + +F + + +L ++
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER------DRKFRE--EEQLRQE 1782
Query: 889 LQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIK 948
+ Q++ Q + RK +++EQ R +E ++ + + R ++EQ+++ +Q+++++
Sbjct: 1783 REEQQLRSQESD----RKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838
Query: 949 --RIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERE 1006
R +Q R E++ Q+ K ++EE ++ +E+E +R+Q +ER+
Sbjct: 1839 QERDRQYRAEEQFATQE-----KSRREE---------QELWQEEEQKRRQ-----ERERK 1879
Query: 1007 RRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLE 1047
R +H + ++K E++ R E + ++ R LE
Sbjct: 1880 LREEH------IRRQQKEEQRHRQVGEIKSQEGKGHGRLLE 1914
Score = 33.5 bits (75), Expect = 2.3
Identities = 24/136 (17%), Positives = 60/136 (44%), Gaps = 22/136 (16%)
Query: 1318 EEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMF 1377
EE ++ ++ ++ + ++E+E + L K+ EKL +++ Q +R+L + LR
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK--- 280
Query: 1378 GQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAESVQIKEEMFETSGDSLN 1437
+E E +E +++++L++ + ++ K+E
Sbjct: 281 -------------------LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 1438 CSNTDHCEQKEDLKEK 1453
+ EQ+E+ +E+
Sbjct: 322 REQQERREQQEERREQ 337
Score = 31.6 bits (70), Expect = 8.8
Identities = 35/194 (18%), Positives = 78/194 (40%), Gaps = 35/194 (18%)
Query: 1286 PGRKRRRK---------GGDSDYDDDDDDDSDDQGDEDDE----------------DEED 1320
PG++RR+K G+ + + + D+ D+E +EE
Sbjct: 133 PGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ 192
Query: 1321 KEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSLRSVMFGQD 1380
+ KG +T+ DE++ + +E K E+ +Q+ + + ++F +
Sbjct: 193 LQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE--------EK 244
Query: 1381 RYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLKKAESVQIKEEMFETSGDSLNCSN 1440
+R+R +L + E E + E+ +E E+L+K E +++ E E
Sbjct: 245 EWRKRETVLRKEEEKLQE--EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 1441 TDHCEQKEDLKEKD 1454
+K++ + ++
Sbjct: 303 EQQLRRKQEEERRE 316
>gi|74027249 tripartite motif-containing 33 protein isoform alpha
[Homo sapiens]
Length = 1127
Score = 89.4 bits (220), Expect = 4e-17
Identities = 69/253 (27%), Positives = 99/253 (39%), Gaps = 80/253 (31%)
Query: 1933 YCQICRKGDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIAKASGQTLKIKKL 1992
+C +C+ G + LL C+ C K H CH P + + P GDW C C + + ++
Sbjct: 889 WCAVCQNGGD---LLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFC------RDIGKPEV 939
Query: 1993 HVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESF 2052
SKKGK +G + +RK
Sbjct: 940 EYDCDNLQHSKKGKTA-------------------QGLSPVDQRK--------------- 965
Query: 2053 TSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIRE 2112
C +L + HE + F PV +P Y K+IKKPMD ST+++
Sbjct: 966 ----------------CERLLLYLYCHELSIEFQEPVPAS-IPNYYKIIKKPMDLSTVKK 1008
Query: 2113 KLS---SGQYPNLETFALDVRLVFDNCETFNE-----------------DDSDIGRAGHN 2152
KL S Y + F DVRL+F NCE FNE DS++ +AG
Sbjct: 1009 KLQKKHSQHYQIPDDFVADVRLIFKNCERFNEMMKVVQVYADTQEINLKADSEVAQAGKA 1068
Query: 2153 MRKYFEKKWTDTF 2165
+ YFE K T+ +
Sbjct: 1069 VALYFEDKLTEIY 1081
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 88.2 bits (217), Expect = 8e-17
Identities = 74/253 (29%), Positives = 130/253 (51%), Gaps = 27/253 (10%)
Query: 836 PRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRK-LQAQEI 894
P+ +E R R N +R E ++RR+K E + + LRK LQA+E
Sbjct: 530 PKCSFVEKERQRLEN--LRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARER 587
Query: 895 ARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIM-------KQQEKI 947
Q + K +K +Q+ A++ ++ +K + AEEK K+K K M KQ+E+
Sbjct: 588 VEQMKEEK--KKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEA 645
Query: 948 KRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERER 1007
+R++ ++ E+E R Q L KKK++E+ K EA++ +++E R++ + +E+ER
Sbjct: 646 RRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQ---ERREQER 702
Query: 1008 RRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAK--------EL 1059
R Q + E ++ E+ER +R+++RL ER+L++R L + K E
Sbjct: 703 REQERREQERREQERQLAEQER----RREQERLQAERELQEREKALRLQKEQLQRELEEK 758
Query: 1060 KKPNEDMCLADQK 1072
KK E LA+++
Sbjct: 759 KKKEEQQRLAERQ 771
Score = 40.4 bits (93), Expect = 0.019
Identities = 41/136 (30%), Positives = 70/136 (51%), Gaps = 28/136 (20%)
Query: 947 IKRIQQIRMEKEL----RAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKH 1002
IKR +RM+ + + +Q LE ++KEEA + ++++E + RR + V LK
Sbjct: 520 IKRNTPLRMDPKCSFVEKERQRLE-NLRRKEEAEQLR----RQKVEEDKRRRLEEVKLKR 574
Query: 1003 QERERR----RQHMMLMKAMEARKKAEEK-------------ERLKQEKRDEKRLNKE-R 1044
+ER R+ R+ + MK E +K+ E+K ERL +EK +K K+
Sbjct: 575 EERLRKVLQARERVEQMKE-EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKME 633
Query: 1045 KLEQRRLELEMAKELK 1060
++E RR + E A+ L+
Sbjct: 634 EVEARRKQEEEARRLR 649
Score = 39.7 bits (91), Expect = 0.032
Identities = 85/474 (17%), Positives = 178/474 (37%), Gaps = 49/474 (10%)
Query: 499 QSVIQEAPLALTTKTKMQSKINENIAAASSTP----FSSPVNLSTSGRRTPGNQTPVMPS 554
+SV++ A L KT + + I S P + + + P PV +
Sbjct: 329 ESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAA 388
Query: 555 ASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEED 614
+ + G N+ + + PA S S ++ + + E +
Sbjct: 389 EPEVPENNGNNSWPHNDTEIANSTPNPKPAAS--------------SPETPSAGQQEAKT 434
Query: 615 DEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGE-----KTS 669
D+ D E S S ++ +E EE+ +D++ S T K
Sbjct: 435 DQA-----DGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVV 489
Query: 670 MKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSP 729
L +V+ M +T S PR++ + + P + + L
Sbjct: 490 RPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKE 549
Query: 730 HSGTSKRRRVTDERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQ-YPEVIK 788
+ +R++V +++ R+ E +RE R+R + K++ Q + ++ +
Sbjct: 550 EAEQLRRQKVEEDKRRRLE-EVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 608
Query: 789 YLSRNGIMDISRDNFSFSAKIRVGDFYEAR----DGPQGMQWCLLKEED-----VIPRIR 839
+ ++ + A + + EAR + + ++W +EE+ ++ + +
Sbjct: 609 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK 668
Query: 840 AMEGRRGRPPNPDRQRAREESRMRR-RKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQA 898
E R R ++ A + + RR ++ R E + + R+L QE R+
Sbjct: 669 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 728
Query: 899 AQIKLLRKLQKQEQA---------RVAKEAKKQQAIMAAEEKRKQKEQIKIMKQ 943
+++ R+LQ++E+A R +E KK++ E++ Q+EQ K K+
Sbjct: 729 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 86.7 bits (213), Expect = 2e-16
Identities = 69/235 (29%), Positives = 123/235 (52%), Gaps = 25/235 (10%)
Query: 854 QRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRK-LQAQEIARQAAQIKLLRKLQKQEQ 912
+R E ++RR+K E + + LRK LQA+E Q + K +K +Q+
Sbjct: 542 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEK--KKQIEQKF 599
Query: 913 ARVAKEAKKQQAIMAAEEKRKQKEQIKIM-------KQQEKIKRIQQIRMEKELRAQQIL 965
A++ ++ +K + AEEK K+K K M KQ+E+ +R++ ++ E+E R Q L
Sbjct: 600 AQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQEL 659
Query: 966 EAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAE 1025
KKK++E+ K EA++ +++E R++ + +E+ERR Q + E ++
Sbjct: 660 LQKKKEEEQERLRKAAEAKRLAEQREQERREQ---ERREQERREQERREQERREQERQLA 716
Query: 1026 EKERLKQEKRDEKRLNKERKLEQRRLELEMAK--------ELKKPNEDMCLADQK 1072
E+ER +R+++RL ER+L++R L + K E KK E LA+++
Sbjct: 717 EQER----RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQ 767
Score = 77.0 bits (188), Expect = 2e-13
Identities = 62/207 (29%), Positives = 117/207 (56%), Gaps = 27/207 (13%)
Query: 885 LLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQ 944
L RK +A+++ RQ + R+L E+ ++ +E + ++ + A +E+++ MK++
Sbjct: 541 LRRKEEAEQLRRQKVEEDKRRRL---EEVKLKREERLRKVLQA-------RERVEQMKEE 590
Query: 945 EKIKRIQQIRM---EKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLK 1001
+K K+I+Q EK +A++ A++K K++AA K+ E E R K++E R+ L+
Sbjct: 591 KK-KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLR-WLQ 648
Query: 1002 HQERERRRQHMM----------LMKAMEARKKAE--EKERLKQEKRDEKRLNKERKLEQR 1049
+E ERR Q ++ L KA EA++ AE E+ER +QE+R+++R +ER+ ++R
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQER 708
Query: 1050 RLELEMAKELKKPNEDMCLADQKPLPE 1076
R + E ++ E L ++ L E
Sbjct: 709 REQERQLAEQERRREQERLQAERELQE 735
Score = 40.4 bits (93), Expect = 0.019
Identities = 86/474 (18%), Positives = 180/474 (37%), Gaps = 53/474 (11%)
Query: 499 QSVIQEAPLALTTKTKMQSKINENIAAASSTP----FSSPVNLSTSGRRTPGNQTPVMPS 554
+SV++ A L KT + + I S P + + + P PV +
Sbjct: 329 ESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAA 388
Query: 555 ASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEED 614
+ + G N+ + + PA S S ++ + + E +
Sbjct: 389 EPEVPENNGNNSWPHNDTEIANSTPNPKPAAS--------------SPETPSAGQQEAKT 434
Query: 615 DEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGE-----KTS 669
D+ D E S S ++ +E EE+ +D++ S T K
Sbjct: 435 DQA-----DGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVV 489
Query: 670 MKLNKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPAALCSESQSPAFLGTSSSTLTSSP 729
L +V+ M +T S PR++ + + P + + + L L
Sbjct: 490 RPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRL----ENLRRKE 545
Query: 730 HSGTSKRRRVTDERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQ-YPEVIK 788
+ +R++V +++ R+ E +RE R+R + K++ Q + ++ +
Sbjct: 546 EAEQLRRQKVEEDKRRRLE-EVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 604
Query: 789 YLSRNGIMDISRDNFSFSAKIRVGDFYEAR----DGPQGMQWCLLKEED-----VIPRIR 839
+ ++ + A + + EAR + + ++W +EE+ ++ + +
Sbjct: 605 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK 664
Query: 840 AMEGRRGRPPNPDRQRAREESRMRR-RKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQA 898
E R R ++ A + + RR ++ R E + + R+L QE R+
Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724
Query: 899 AQIKLLRKLQKQEQA---------RVAKEAKKQQAIMAAEEKRKQKEQIKIMKQ 943
+++ R+LQ++E+A R +E KK++ E++ Q+EQ K K+
Sbjct: 725 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
Score = 34.7 bits (78), Expect = 1.0
Identities = 31/164 (18%), Positives = 76/164 (46%), Gaps = 12/164 (7%)
Query: 910 QEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIK--RIQQIRME---KELRAQQI 964
Q++A+ + ++ +A KR K+ + + +++ ++ +Q R + A ++
Sbjct: 429 QQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKV 488
Query: 965 LEAKKKKKEEAANAKLL----EAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEA 1020
+ + ++L A + + + ++R + + +E+ER+R + K
Sbjct: 489 VRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAE 548
Query: 1021 RKKAEEKERLKQEKRDEKRLNKE---RKLEQRRLELEMAKELKK 1061
+ + ++ E K+ + +E +L +E RK+ Q R +E KE KK
Sbjct: 549 QLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 592
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 78.2 bits (191), Expect = 8e-14
Identities = 81/338 (23%), Positives = 166/338 (49%), Gaps = 35/338 (10%)
Query: 753 WQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVG 812
W++E +I+ + ++Q + +K+R+ E ++ R M ++ + +
Sbjct: 364 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQEEMMW 420
Query: 813 DFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNV 872
+ E + M W KEE +IR +E + ++ R +EE R K R
Sbjct: 421 EKEEKMRRQEEMMW--EKEE----KIRELEEKMHEQ---EKIREQEEKRQEEEKIR---- 467
Query: 873 GNAEFLDNADAKLLR---KLQAQEIARQAAQIKLLR---KLQKQEQARVAKEAKKQQAIM 926
E +AK+ R K++ QE + + K+ R K+ +QE+ R ++ ++Q+ +
Sbjct: 468 -EQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMW 526
Query: 927 AAEEKRKQKEQI-----KIMKQQEKIKRIQQ--IRMEKELRAQQILEAKKKKKEEAANAK 979
EEK +++E+I KI +Q+EKI++ ++ R E+++ Q+ ++++K K
Sbjct: 527 RQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEK 586
Query: 980 LLEAEKRIKEKEMR-RQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEK 1038
+ E E++I+E+E + R+Q + + QE + Q + + E ++ EEK R ++EK E+
Sbjct: 587 IREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ 646
Query: 1039 ----RLNKERKLEQRRLELEMAKELKKPNEDMCLADQK 1072
R +E+ EQ + E +++ + E MC ++K
Sbjct: 647 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 684
Score = 70.5 bits (171), Expect = 2e-11
Identities = 56/195 (28%), Positives = 118/195 (60%), Gaps = 15/195 (7%)
Query: 886 LRKLQAQEIARQAAQIKLLR-KLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQ 944
L + Q +++ RQ +I+ K+Q+QE+ K ++++ I EEK +++E++ + +++
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEE----KIREQEEKIREQEEKMRRQEEM-MWEKE 409
Query: 945 EKIKRIQQIRMEKE--LRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKH 1002
EK++R +++ EKE +R Q+ + +K++K K+ E EK I+E+E +RQ+ ++
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIRE 468
Query: 1003 QERERRRQHMMLMKAMEARKKAEEKERLKQEK--RDEKRLNKERKL---EQRRLELEMAK 1057
QE+ R+ Q + + E ++ EEK R ++EK R E++++++ K+ E+R+ + EM +
Sbjct: 469 QEK-RQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWR 527
Query: 1058 ELKKPNEDMCLADQK 1072
+ +K E + QK
Sbjct: 528 QEEKIREQEEIWRQK 542
Score = 68.9 bits (167), Expect = 5e-11
Identities = 60/206 (29%), Positives = 108/206 (52%), Gaps = 29/206 (14%)
Query: 876 EFLDNADAKLLRKLQAQEIARQAAQI---KLLRKL--------QKQEQARVAKEAKKQQA 924
E L +AKL KLQ E + Q+ +L RKL Q+Q QA K+ Q+
Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337
Query: 925 IMA-----AEEKR-----KQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEE 974
+ A EE Q+++ K+ +Q+EKI+ ++ E+E ++I E ++K +E+
Sbjct: 338 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE---EKIREQEEKIREQ 394
Query: 975 AANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMML---MKAMEARKKAEEKERLK 1031
+ E KE++MRRQ+ ++ + +E+ RR++ MM K E +K E+E+++
Sbjct: 395 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIR 454
Query: 1032 QEKRDEKRLNKERKLEQRRLELEMAK 1057
++ +EKR +E+ EQ + + + AK
Sbjct: 455 EQ--EEKRQEEEKIREQEKRQEQEAK 478
Score = 64.7 bits (156), Expect = 9e-10
Identities = 80/338 (23%), Positives = 164/338 (48%), Gaps = 46/338 (13%)
Query: 742 ERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRD 801
E ++R E W++E ++R Q E+ + +K+R+ E + + + R
Sbjct: 409 EEKMRRQEEMMWEKEEKMRR-----QEEMMWEKE--EKIRELEEKMHEQEKIREQEEKRQ 461
Query: 802 NFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESR 861
KIR + + ++ Q ++E++ +IR E + R ++ E+ +
Sbjct: 462 E---EEKIREQEKRQEQEAKMWRQEEKIREQE--EKIREQEEKMWR----QEEKIHEQEK 512
Query: 862 MRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQI-KLLRKLQKQEQARVAKEAK 920
+R + R E + + K+ + +EI RQ +I + K++KQE+ +E K
Sbjct: 513 IREEEKRQEQ----EEMWRQEEKIREQ---EEIWRQKEKIHEQEEKIRKQEEKMWRQEEK 565
Query: 921 KQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQ-IR-MEKELRAQQILEAKKKKKEEAANA 978
EEK +++E+ K+ +Q+EKI+ ++ IR E+++R Q+ + ++++K
Sbjct: 566 MHDQ----EEKIREQEE-KVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Query: 979 KLLEAEKRIKEKE--MRRQQAVL------LKHQERERRRQHMMLM----KAMEARKKAEE 1026
K+ E E++++E+E MRRQ+ + ++ QE + R Q M+ K E +K E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680
Query: 1027 KERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNE 1064
+E QE+ ++ R +E+ EQ E+ + ++ +K E
Sbjct: 681 QEEKMQEQEEKMRRQEEKMWEQ---EVRLRQQEEKMQE 715
Score = 64.3 bits (155), Expect = 1e-09
Identities = 47/201 (23%), Positives = 111/201 (55%), Gaps = 22/201 (10%)
Query: 887 RKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAK--KQQAIMAAEEKRKQKEQIKIMKQQ 944
++ + +E+ RQ +I+ ++ +Q++ +E K KQ+ M +E++ ++ KI +Q+
Sbjct: 518 KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577
Query: 945 EKI-KRIQQIR--------MEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKE--MR 993
EK+ ++ ++IR E+++R Q+ + ++++K K+ E E++++E+E MR
Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR 637
Query: 994 RQQAVL------LKHQERERRRQHMMLMKAMEARKKAEEK---ERLKQEKRDEKRLNKER 1044
RQ+ + ++ QE + R Q M+ + E + EEK + K ++++EK +E
Sbjct: 638 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Query: 1045 KLEQRRLELEMAKELKKPNED 1065
K+ ++ + L +E + +++
Sbjct: 698 KMWEQEVRLRQQEEKMQEHQE 718
Score = 57.0 bits (136), Expect = 2e-07
Identities = 46/195 (23%), Positives = 102/195 (52%), Gaps = 26/195 (13%)
Query: 906 KLQKQEQARVAKEAK--KQQAIMAAEEKR------KQKEQIKIMKQQEKIKRIQQIRMEK 957
K+++QE+ KE K +Q+ +M +E++ K EQ KI +Q+EK + ++IR ++
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470
Query: 958 ELRAQQILEAKKKKKEEAANAKLLEAE-------------KRIKEKEMRRQQAVLLKHQE 1004
+ + Q+ ++++K K+ E E ++I+E+E R++Q + + +E
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Query: 1005 RERRRQHMMLMKAMEARKKAEEKERLKQEK---RDEKRLNKERKLEQRRLELEMAKELKK 1061
+ R ++ + K E + EEK R ++EK ++EK ++E K+ ++ ++ +E +
Sbjct: 531 KIREQEEIWRQK--EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 1062 PNEDMCLADQKPLPE 1076
E+ ++ + E
Sbjct: 589 EQEEKIREQEEKIRE 603
Score = 53.1 bits (126), Expect = 3e-06
Identities = 59/216 (27%), Positives = 100/216 (46%), Gaps = 51/216 (23%)
Query: 896 RQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRI----- 950
R A ++L R E+ + K AK Q+ + E + K + Q+ + + + K++R
Sbjct: 263 RDALSLELYRNTITDEELK-EKNAKLQEKLQLVESE-KSEIQLNVKELKRKLERAKLLLP 320
Query: 951 -QQIRME-----KEL------------------RAQQILEAKKKKKEEAA---NAKLLEA 983
QQ++ E KEL R Q E K ++EE K+ E
Sbjct: 321 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 380
Query: 984 EKRIKEKE---------MRRQQAVLLKHQERERRRQHMMLMKAMEARK------KAEEKE 1028
E++I+E+E MRRQ+ ++ + +E+ RR++ MM K + R+ + EEK
Sbjct: 381 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKI 440
Query: 1029 RLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNE 1064
R +EK E+ K R+ E++R E E +E +K E
Sbjct: 441 RELEEKMHEQ--EKIREQEEKRQEEEKIREQEKRQE 474
Score = 38.1 bits (87), Expect = 0.095
Identities = 34/152 (22%), Positives = 77/152 (50%), Gaps = 9/152 (5%)
Query: 1306 DSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKL 1365
+ +++ E +E +E+K ++ I E+E +Q EE+ +Q EK+ +Q+ +R+K
Sbjct: 488 EQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQ----EEMWRQEEKIREQEEIWRQK- 542
Query: 1366 FDASHSLRSVMFGQDR--YRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLK-KAESV 1422
+ H + Q+ +R+ + Q I + + E+I ++ EK++ + E +
Sbjct: 543 -EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKI 601
Query: 1423 QIKEEMFETSGDSLNCSNTDHCEQKEDLKEKD 1454
+ +EEM + + + CEQ+E ++E++
Sbjct: 602 REQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 633
Score = 32.0 bits (71), Expect = 6.8
Identities = 28/144 (19%), Positives = 66/144 (45%), Gaps = 3/144 (2%)
Query: 1313 EDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHSL 1372
E +E +E+K ++ + D++E + E++ +Q EK+ +Q+ + R +
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQE-EKVWRQEEKIREQEEKIREQEEKIREQE 605
Query: 1373 RSVMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKL--KKAESVQIKEEMFE 1430
+++ + + + E E EE +E+EK ++ E ++ +EEM +
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 1431 TSGDSLNCSNTDHCEQKEDLKEKD 1454
+ + CEQ+E ++E++
Sbjct: 666 EQEEKMWEQEEKMCEQEEKMQEQE 689
>gi|148612882 cat eye syndrome chromosome region, candidate 2 [Homo
sapiens]
Length = 1484
Score = 77.8 bits (190), Expect = 1e-13
Identities = 45/154 (29%), Positives = 76/154 (49%), Gaps = 19/154 (12%)
Query: 2021 STSSSLKRGNKDLKKRKMEENTSINLSKQE------SFTSVKKPKRDDSK---------D 2065
STS + R K+RK+ E + L++ + S P R++ K D
Sbjct: 384 STSRPVDRA----KRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDLFELDDD 439
Query: 2066 LALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLETF 2125
+L ++ H+D+WPFL PV+ P Y ++IK PMD S++ +KL+ G Y E F
Sbjct: 440 FTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEF 499
Query: 2126 ALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEK 2159
D++ +F NC +N + S+ + N+ + F +
Sbjct: 500 VNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHR 533
Score = 33.5 bits (75), Expect = 2.3
Identities = 59/251 (23%), Positives = 102/251 (40%), Gaps = 42/251 (16%)
Query: 844 RRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKL 903
RRGRPP R++ +EE + ++ + L + Q + ++ Q
Sbjct: 200 RRGRPPK--RKKLQEEILLSEKQ--------------EENSLASEPQTRHGSQGPGQGTW 243
Query: 904 LRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQ----------EKIKRIQQI 953
Q +E+ R E+ +++ + ++++ K++ + +K KR Q+
Sbjct: 244 WLLCQTEEEWRQVTESFRERTSL------RERQLYKLLSEDFLPEICNMIAQKGKRPQRT 297
Query: 954 RMEKELR-AQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRR-QQAVLLKHQER----ER 1007
+ E R L K K+EE +E +KR +E+E R+ AV K QE+ ER
Sbjct: 298 KAELHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEER 357
Query: 1008 RRQHMMLMKAMEARKKAEEKER--LKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNED 1065
+R+ +KA+E R R R + + E+R L KEL P E
Sbjct: 358 KRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKEL--PPEL 415
Query: 1066 MCLADQKPLPE 1076
L P+ E
Sbjct: 416 SHLDPNSPMRE 426
Score = 33.5 bits (75), Expect = 2.3
Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 12/127 (9%)
Query: 810 RVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRP 869
+V + + R + Q L ED +P I M ++G+ P QR + E R
Sbjct: 255 QVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRP----QRTKAELHPRWMSDHL 310
Query: 870 PNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAE 929
+ + + + +L +++ Q+ + + ++L +QK+EQ ++ KE +K++ E
Sbjct: 311 ----SIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRE----LE 362
Query: 930 EKRKQKE 936
EK K E
Sbjct: 363 EKVKAVE 369
>gi|40805843 K(lysine) acetyltransferase 2B [Homo sapiens]
Length = 832
Score = 76.3 bits (186), Expect = 3e-13
Identities = 35/104 (33%), Positives = 60/104 (57%)
Query: 2057 KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSS 2116
K RD + + IL ++++H+ AWPF+ PV PGY +VI+ PMD T+ E+L +
Sbjct: 720 KEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKN 779
Query: 2117 GQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
Y + + F D++ VF NC+ +N +S+ + + + K+F K
Sbjct: 780 RYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCANILEKFFFSK 823
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 74.7 bits (182), Expect = 9e-13
Identities = 82/344 (23%), Positives = 167/344 (48%), Gaps = 42/344 (12%)
Query: 753 WQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRDNFSFSAKIRVG 812
W++E +I+ + ++Q + +K+R+ E ++ R M ++ + +
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMR---RQEEMMWEKEEKMRRQEEMMW 359
Query: 813 DFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNV 872
+ E + M W KEE +IR +E + ++ R +EE R K R
Sbjct: 360 EKEEKMRRLEEMMW--EKEE----KIRELEEKMHEQ---EKIREQEEKRQEEEKIR---- 406
Query: 873 GNAEFLDNADAKLLR---KLQAQEIARQAAQIKLLR---KLQKQEQARVAKEAKKQQAIM 926
E +AK+ R K++ QE + + K+ R K+ +QE+ R ++ ++Q+ +
Sbjct: 407 -EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMW 465
Query: 927 AAEEKRKQKEQI-----------KIMKQQEKIKRIQQIRM---EKELRAQQILEAKKKKK 972
EEK +++E+I KI KQ+EK+ R Q+ +M E+++R Q+ ++++K
Sbjct: 466 RQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWR-QEEKMHDQEEKIREQEEKMWRQEEK 524
Query: 973 EEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQ 1032
K+ E E++I+E+E Q+ ++ E+ ++ + + E ++ EEK R ++
Sbjct: 525 IREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584
Query: 1033 EK---RDEKRLNKERKL-EQRRLELEMAKELKKPNEDMCLADQK 1072
EK ++EK +E K+ EQ + E +++ + E MC ++K
Sbjct: 585 EKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 628
Score = 67.8 bits (164), Expect = 1e-10
Identities = 60/206 (29%), Positives = 107/206 (51%), Gaps = 29/206 (14%)
Query: 876 EFLDNADAKLLRKLQAQEIARQAAQI---KLLRKL--------QKQEQARVAKEAKKQQA 924
E L +AKL KLQ E + Q+ +L RKL Q+Q QA K+ Q+
Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276
Query: 925 IMA-----AEEKR-----KQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEE 974
+ A EE Q+++ K+ +Q+EKI+ ++ E+E ++I E ++K +E+
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE---EKIREQEEKIREQ 333
Query: 975 AANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMML---MKAMEARKKAEEKERLK 1031
+ E KE++MRRQ+ ++ + +E+ RR + MM K E +K E+E+++
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIR 393
Query: 1032 QEKRDEKRLNKERKLEQRRLELEMAK 1057
++ +EKR +E+ EQ + + + AK
Sbjct: 394 EQ--EEKRQEEEKIREQEKRQEQEAK 417
Score = 67.0 bits (162), Expect = 2e-10
Identities = 56/228 (24%), Positives = 120/228 (52%), Gaps = 28/228 (12%)
Query: 858 EESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAK 917
+E +MRR++ E + + K+ R+L+ ++ +L K+ +QE+ R +
Sbjct: 347 KEEKMRRQE---------EMMWEKEEKM-RRLEEMMWEKEEKIRELEEKMHEQEKIR-EQ 395
Query: 918 EAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAAN 977
E K+Q+ E++++Q+++ K+ +Q+EKI+ E+++R Q E K ++EE +
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE-----QEEKIREQ---EKKMWRQEEKIH 447
Query: 978 A--KLLEAEKRIKEKEMRRQQAVLLKHQE----RERRRQHMMLMKAMEARKKAEEKERLK 1031
K+ E EKR +++EM RQ+ + + +E +E+ + + K E + EEK +
Sbjct: 448 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ 507
Query: 1032 QEK---RDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPE 1076
+EK ++EK +E K+ ++ ++ +E + E+M ++ + E
Sbjct: 508 EEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555
Score = 65.9 bits (159), Expect = 4e-10
Identities = 53/189 (28%), Positives = 107/189 (56%), Gaps = 20/189 (10%)
Query: 888 KLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKK----QQAIMAAEEKRKQKEQIKIMKQ 943
KLQAQ + +L +L +Q++ ++ ++ +K ++ I EEK +++E+ KI +Q
Sbjct: 280 KLQAQ-----VEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE-KIREQ 333
Query: 944 QEKIKRIQQIRMEKE--LRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLK 1001
+EK++R +++ EKE +R Q+ + +K++K + E E++I+E E + + K
Sbjct: 334 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQE--K 391
Query: 1002 HQERERRRQHMMLMKAMEARKKAEEKERLKQEK---RDEKRLNKERKL---EQRRLELEM 1055
+E+E +RQ ++ E R++ E K ++EK ++EK +E+K+ E++ E E
Sbjct: 392 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEK 451
Query: 1056 AKELKKPNE 1064
+E +K E
Sbjct: 452 IREEEKRQE 460
Score = 65.9 bits (159), Expect = 4e-10
Identities = 43/201 (21%), Positives = 113/201 (56%), Gaps = 14/201 (6%)
Query: 886 LRKLQAQEIARQAAQIKLLR-KLQKQEQARVAKEAK---------KQQAIMAAEEKRKQK 935
L + Q +++ RQ +I+ K+Q+QE+ +E K +Q+ +M +E++ ++
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 936 EQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995
++ + +++EK++R++++ EKE + +++ E ++++ + + E++I+E+E R++
Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 413
Query: 996 QAVLLKHQERERRRQHMML----MKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRL 1051
Q + QE + R Q + K +K E+E++++E++ +++ R+ E+ R
Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473
Query: 1052 ELEMAKELKKPNEDMCLADQK 1072
+ E+ ++ +K +E + Q+
Sbjct: 474 QEEIWRQKEKMHEQEKIRKQE 494
Score = 65.9 bits (159), Expect = 4e-10
Identities = 75/338 (22%), Positives = 159/338 (47%), Gaps = 41/338 (12%)
Query: 742 ERELRIPLEYGWQRETRIRNFGGRLQGEVAYYAPCGKKLRQYPEVIKYLSRNGIMDISRD 801
E ++R E W++E ++R + + +K+R+ E + + + R
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKE-------EKIRELEEKMHEQEKIREQEEKRQ 400
Query: 802 NFSFSAKIRVGDFYEARDGPQGMQWCLLKEEDVIPRIRAMEGRRGRPPNPDRQRAREESR 861
KIR + + ++ Q ++E++ +IR E + R ++ E+ +
Sbjct: 401 E---EEKIREQEKRQEQEAKMWRQEEKIREQE--EKIREQEKKMWR----QEEKIHEQEK 451
Query: 862 MRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAK- 920
+R + R E + + K+ + +EI RQ ++ K++KQE+ +E K
Sbjct: 452 IREEEKRQEQ----EEMWRQEEKIREQ---EEIWRQKEKMHEQEKIRKQEEKVWRQEEKM 504
Query: 921 --------KQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR-AQQILEAKKKK 971
+Q+ M +E++ ++++ KI +Q+EKI+ +++ E+E + +Q + ++++
Sbjct: 505 HDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564
Query: 972 KEEAANAKLLEAEKRIKE-KEMRRQQAVLLKHQERERRRQHMMLM----KAMEARKKAEE 1026
K K+ E E++I+E KE R+Q + QE + R Q M+ K E +K E
Sbjct: 565 KMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCE 624
Query: 1027 KERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNE 1064
+E QE+ ++ R +E+ EQ E+ + ++ +K E
Sbjct: 625 QEEKMQEQEEKMRRQEEKMWEQ---EVRLRQQEEKMQE 659
Score = 64.7 bits (156), Expect = 9e-10
Identities = 56/213 (26%), Positives = 114/213 (53%), Gaps = 24/213 (11%)
Query: 854 QRAREESRMRRRKGRPPNVGNAEFLDNADAKLLR---KLQAQEIARQAAQIKLLRKLQK- 909
++ RE+ + R+K + + E + + K+ R K+ QE + + K+ R+ +K
Sbjct: 469 EKIREQEEIWRQKEK---MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKI 525
Query: 910 ---QEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILE 966
+E+ R +E ++Q M E++ K EQ + M++QEK++R ++ E+E ++I E
Sbjct: 526 REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQE---EKIRE 582
Query: 967 AKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEE 1026
K+K +E+ K+ E E++I+E+E +++ QE + Q + + E ++ EE
Sbjct: 583 QKEKIREQ--EEKIWEQEEKIREQE------EMMQEQEEKMWEQEEKMCEQEEKMQEQEE 634
Query: 1027 KERLKQEKRDEKRL---NKERKLEQRRLELEMA 1056
K R ++EK E+ + +E K+++ + LE A
Sbjct: 635 KMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 667
Score = 53.1 bits (126), Expect = 3e-06
Identities = 59/216 (27%), Positives = 100/216 (46%), Gaps = 51/216 (23%)
Query: 896 RQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRI----- 950
R A ++L R E+ + K AK Q+ + E + K + Q+ + + + K++R
Sbjct: 202 RDALSLELYRNTITDEELK-EKNAKLQEKLQLVESE-KSEIQLNVKELKRKLERAKLLLP 259
Query: 951 -QQIRME-----KEL------------------RAQQILEAKKKKKEEAA---NAKLLEA 983
QQ++ E KEL R Q E K ++EE K+ E
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 984 EKRIKEKE---------MRRQQAVLLKHQERERRRQHMMLMKAMEARK------KAEEKE 1028
E++I+E+E MRRQ+ ++ + +E+ RR++ MM K + R+ + EEK
Sbjct: 320 EEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKI 379
Query: 1029 RLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNE 1064
R +EK E+ K R+ E++R E E +E +K E
Sbjct: 380 RELEEKMHEQ--EKIREQEEKRQEEEKIREQEKRQE 413
Score = 34.7 bits (78), Expect = 1.0
Identities = 30/144 (20%), Positives = 70/144 (48%), Gaps = 12/144 (8%)
Query: 1312 DEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKLFDASHS 1371
+E D+E+K ++ +K ++E +Q + E E++I + + + K+ +
Sbjct: 501 EEKMHDQEEKIREQEEKM-WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEK 559
Query: 1372 LRSVMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKL-KKAESVQIKEEMFE 1430
++ Q++ RR Q I + + E E+I ++ EK+ ++ E ++ +EEM +
Sbjct: 560 MQE----QEKMRR------QEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ 609
Query: 1431 TSGDSLNCSNTDHCEQKEDLKEKD 1454
+ + CEQ+E ++E++
Sbjct: 610 EQEEKMWEQEEKMCEQEEKMQEQE 633
Score = 32.7 bits (73), Expect = 4.0
Identities = 43/218 (19%), Positives = 101/218 (46%), Gaps = 21/218 (9%)
Query: 1246 WVVEGKLRKLRIIHAKKTGK-RDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDD 1304
W E K+R+L + +K K R+ + EQ + R+ K + + + +
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKM---HEQEKIREQEEKRQEEEKIREQEKRQEQE 415
Query: 1305 DDSDDQGDEDDEDEE---DKEDKKGKKTDICEDED---EGDQAASVEELEKQIEKLSKQQ 1358
Q ++ E EE ++E K ++ + +++ E ++ EE+ +Q EK+ +Q+
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQE 475
Query: 1359 SQYRRKLFDASHSLRSVMFGQDR-YRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKLK 1417
+R+K + H + +++ +R+ + Q I + + E+I ++ EK++
Sbjct: 476 EIWRQK--EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR 533
Query: 1418 -KAESVQIKEEMFETSGDSLNCSNTDHCEQKEDLKEKD 1454
+ E ++ +EEM + + + EQ+E ++E++
Sbjct: 534 EQEEKIREQEEMMQEQEEKMG-------EQEEKMQEQE 564
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 73.9 bits (180), Expect = 2e-12
Identities = 33/84 (39%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 601 SKDSEDSNEDEEEDDEEEDEEDDED-DESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659
S+ ED EDE+++DE+E+EEDDE+ D S+D S+S+SE ++E +E ++DD+D+D+
Sbjct: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 697
Query: 660 DSDTEGEKTSMKLNKTTSSVKSPS 683
+ D E E + + ++SS S
Sbjct: 698 EDDDEDEDNESEGSSSSSSSSGDS 721
Score = 70.1 bits (170), Expect = 2e-11
Identities = 31/79 (39%), Positives = 48/79 (60%)
Query: 600 SSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659
S +D E+ +DE+ED+EEED+E+ + E SES S ES+ EEDD+D+D DE
Sbjct: 640 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDED 699
Query: 660 DSDTEGEKTSMKLNKTTSS 678
D + E ++ + ++SS
Sbjct: 700 DDEDEDNESEGSSSSSSSS 718
Score = 65.1 bits (157), Expect = 7e-10
Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
Query: 568 VSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEE-DDEEEDEEDDEDD 626
+SN + +P S ++S+ +D +D +EDEEE DDE D +D D
Sbjct: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
Query: 627 ESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKS 681
S+ S + + + + E E+EDDD+ D ++ D+++EG +S + +S S
Sbjct: 672 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726
Score = 58.9 bits (141), Expect = 5e-08
Identities = 24/68 (35%), Positives = 41/68 (60%)
Query: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
D + SS+D DS+E ED+ E+ +E++EDDE +D + D + ++++EGS
Sbjct: 660 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719
Query: 655 DQDESDSD 662
D +SDS+
Sbjct: 720 DSSDSDSN 727
Score = 55.8 bits (133), Expect = 4e-07
Identities = 25/60 (41%), Positives = 42/60 (70%), Gaps = 2/60 (3%)
Query: 593 GTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDD 652
G S+ S +SED +E+EE+D++E+D+EDD++DE D++SE S+S S + S + D +
Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE--DNESEGSSSSSSSSGDSSDSDSN 727
Score = 53.1 bits (126), Expect = 3e-06
Identities = 21/79 (26%), Positives = 38/79 (48%)
Query: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
D + ++ +D N D ED + E ED+ D ++E D E D E +E++D++
Sbjct: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708
Query: 655 DQDESDSDTEGEKTSMKLN 673
+ S S + G+ + N
Sbjct: 709 EGSSSSSSSSGDSSDSDSN 727
Score = 52.8 bits (125), Expect = 4e-06
Identities = 29/91 (31%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
Query: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDL 268
+R Q +S+++ D + +D+ ++ E+ +S+ D G SS++SSE S D D+
Sbjct: 630 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE-DGGDSSESSSED-ESEDGDEN 687
Query: 269 EEDEEEEDQSIEESEDDDSDSESEAQHKSNN 299
EED+E+ED ++ ED+D++SE + S++
Sbjct: 688 EEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
Score = 42.7 bits (99), Expect = 0.004
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 1236 DYMSNLRRDKWVVEGKLRKLR--IIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRK 1293
+Y+SN R+ + G K + +K + D D +E G
Sbjct: 610 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 669
Query: 1294 GGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQA 1341
G S+ +D+ + D+ +EDDEDE+D ED +DEDE +++
Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDEDDDED---------DDEDEDNES 708
Score = 42.4 bits (98), Expect = 0.005
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
P P R S+ ++DD++D DD +DEDEE+++D+ G D ED + +++S
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDEDD----EDEDEEEEDDENG---DSSEDGGDSSESSS 677
Query: 1344 VEELE 1348
+E E
Sbjct: 678 EDESE 682
Score = 41.2 bits (95), Expect = 0.011
Identities = 17/63 (26%), Positives = 32/63 (50%)
Query: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
P R + +S+ DD++D+D +D+ +E+++DE + G + EDE +
Sbjct: 627 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE 686
Query: 1344 VEE 1346
EE
Sbjct: 687 NEE 689
Score = 40.0 bits (92), Expect = 0.025
Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 229 IKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEE-DQSIEESEDDDS 287
I +K+ + + S + S + SE D DD +EDEEEE D++ + SED
Sbjct: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
Query: 288 DSESEAQHKSNN 299
SES ++ +S +
Sbjct: 672 SSESSSEDESED 683
Score = 38.9 bits (89), Expect = 0.055
Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 19/195 (9%)
Query: 884 KLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQ 943
+ L L +E R + K+L + K++ A + Q+ EK K+ +
Sbjct: 323 RFLESLPEEEQQRVLGEEKMLN-INKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 381
Query: 944 QEKIKRIQQIR---MEKEL-----RAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995
+EK +++Q+ R E EL R L KKK K +A A L+A+ K R +
Sbjct: 382 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREA-ALKAQSERKPGGEREE 440
Query: 996 QAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKL--------E 1047
+ L + +R ++ AR K + + LK + + K+ KL +
Sbjct: 441 RGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED 500
Query: 1048 QRRLELEMAKELKKP 1062
Q+R E E++ E++ P
Sbjct: 501 QKRYERELS-EMRAP 514
Score = 38.5 bits (88), Expect = 0.072
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 228 KIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDS 287
K++ P+ S S+S+ D E D D+ EED+E D S + + +S
Sbjct: 621 KLRGPNPKSSRTTLQSKSESEEDDEEDEDDE-----DEDEEEEDDENGDSSEDGGDSSES 675
Query: 288 DSESEAQHKSNNQ 300
SE E++ N+
Sbjct: 676 SSEDESEDGDENE 688
Score = 37.4 bits (85), Expect = 0.16
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 1279 HPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDE- 1337
+P + T + + D + D+DD+D +D+ +EDDE+ + ED EDE E
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDED--EDEEEEDDENGDSSEDGGDSSESSSEDESED 683
Query: 1338 GDQAASVEELEKQIE 1352
GD+ +E E E
Sbjct: 684 GDENEEDDEDEDDDE 698
Score = 37.0 bits (84), Expect = 0.21
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
Query: 231 DKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSE 290
D++ E D ++G SS+ + SS D+ E+ +E E E+ ED+D D +
Sbjct: 644 DEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE----EDDEDEDDDED 699
Query: 291 SEAQHKSNNQ 300
+ + ++
Sbjct: 700 DDEDEDNESE 709
Score = 36.6 bits (83), Expect = 0.28
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Query: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLS 1355
+ + DD++ D S+D GD + ED+ + + + +DEDE D E+ + + E S
Sbjct: 655 EEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE--DDEDEDDDEDDDEDEDNESEGSS 712
Query: 1356 KQQS 1359
S
Sbjct: 713 SSSS 716
Score = 36.6 bits (83), Expect = 0.28
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 1295 GDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDED 1336
GD + +DD+D+D D+ DED+++E + + D D
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 36.2 bits (82), Expect = 0.36
Identities = 15/78 (19%), Positives = 36/78 (46%)
Query: 1283 TPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAA 1342
T + + + D DD+D+D+ ++ + D E+ + + D ED DE ++
Sbjct: 632 TTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDD 691
Query: 1343 SVEELEKQIEKLSKQQSQ 1360
E+ ++ ++ +S+
Sbjct: 692 EDEDDDEDDDEDEDNESE 709
Score = 35.8 bits (81), Expect = 0.47
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGD 1339
D D +++DD+D DD D DDEDE+++ + + D + D
Sbjct: 683 DGDENEEDDEDEDDDED-DDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 34.7 bits (78), Expect = 1.0
Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 6/132 (4%)
Query: 196 SMGQTKSTSSGGGNRKCNQEQSKNQP--LDARVDKI--KDKKPRKKAMESSSNSDSDSGT 251
S Q S S +K +EQ K LD V + +D+ K+ + + S +
Sbjct: 565 SRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRG 624
Query: 252 SSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKA 311
+ SS S S+ E+DEE+ED E+ E++D ++ ++ ++ D
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE--SSSEDESE 682
Query: 312 DGQKATEKAQEK 323
DG + E +++
Sbjct: 683 DGDENEEDDEDE 694
Score = 33.1 bits (74), Expect = 3.0
Identities = 15/56 (26%), Positives = 27/56 (48%)
Query: 581 SHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESD 636
S + S E G +++ + +D ++DE+ED+E E D S S+S+
Sbjct: 672 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 73.9 bits (180), Expect = 2e-12
Identities = 33/84 (39%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 601 SKDSEDSNEDEEEDDEEEDEEDDED-DESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659
S+ ED EDE+++DE+E+EEDDE+ D S+D S+S+SE ++E +E ++DD+D+D+
Sbjct: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 697
Query: 660 DSDTEGEKTSMKLNKTTSSVKSPS 683
+ D E E + + ++SS S
Sbjct: 698 EDDDEDEDNESEGSSSSSSSSGDS 721
Score = 70.1 bits (170), Expect = 2e-11
Identities = 31/79 (39%), Positives = 48/79 (60%)
Query: 600 SSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659
S +D E+ +DE+ED+EEED+E+ + E SES S ES+ EEDD+D+D DE
Sbjct: 640 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDED 699
Query: 660 DSDTEGEKTSMKLNKTTSS 678
D + E ++ + ++SS
Sbjct: 700 DDEDEDNESEGSSSSSSSS 718
Score = 65.1 bits (157), Expect = 7e-10
Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
Query: 568 VSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEE-DDEEEDEEDDEDD 626
+SN + +P S ++S+ +D +D +EDEEE DDE D +D D
Sbjct: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
Query: 627 ESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKS 681
S+ S + + + + E E+EDDD+ D ++ D+++EG +S + +S S
Sbjct: 672 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 726
Score = 58.9 bits (141), Expect = 5e-08
Identities = 24/68 (35%), Positives = 41/68 (60%)
Query: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
D + SS+D DS+E ED+ E+ +E++EDDE +D + D + ++++EGS
Sbjct: 660 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 719
Query: 655 DQDESDSD 662
D +SDS+
Sbjct: 720 DSSDSDSN 727
Score = 55.8 bits (133), Expect = 4e-07
Identities = 25/60 (41%), Positives = 42/60 (70%), Gaps = 2/60 (3%)
Query: 593 GTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDD 652
G S+ S +SED +E+EE+D++E+D+EDD++DE D++SE S+S S + S + D +
Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE--DNESEGSSSSSSSSGDSSDSDSN 727
Score = 53.1 bits (126), Expect = 3e-06
Identities = 21/79 (26%), Positives = 38/79 (48%)
Query: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
D + ++ +D N D ED + E ED+ D ++E D E D E +E++D++
Sbjct: 649 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 708
Query: 655 DQDESDSDTEGEKTSMKLN 673
+ S S + G+ + N
Sbjct: 709 EGSSSSSSSSGDSSDSDSN 727
Score = 52.8 bits (125), Expect = 4e-06
Identities = 29/91 (31%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
Query: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDL 268
+R Q +S+++ D + +D+ ++ E+ +S+ D G SS++SSE S D D+
Sbjct: 630 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE-DGGDSSESSSED-ESEDGDEN 687
Query: 269 EEDEEEEDQSIEESEDDDSDSESEAQHKSNN 299
EED+E+ED ++ ED+D++SE + S++
Sbjct: 688 EEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 718
Score = 42.7 bits (99), Expect = 0.004
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 1236 DYMSNLRRDKWVVEGKLRKLR--IIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRK 1293
+Y+SN R+ + G K + +K + D D +E G
Sbjct: 610 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 669
Query: 1294 GGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQA 1341
G S+ +D+ + D+ +EDDEDE+D ED +DEDE +++
Sbjct: 670 GDSSESSSEDESEDGDENEEDDEDEDDDED---------DDEDEDNES 708
Score = 42.4 bits (98), Expect = 0.005
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
P P R S+ ++DD++D DD +DEDEE+++D+ G D ED + +++S
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDEDD----EDEDEEEEDDENG---DSSEDGGDSSESSS 677
Query: 1344 VEELE 1348
+E E
Sbjct: 678 EDESE 682
Score = 41.2 bits (95), Expect = 0.011
Identities = 17/63 (26%), Positives = 32/63 (50%)
Query: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
P R + +S+ DD++D+D +D+ +E+++DE + G + EDE +
Sbjct: 627 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE 686
Query: 1344 VEE 1346
EE
Sbjct: 687 NEE 689
Score = 40.0 bits (92), Expect = 0.025
Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 229 IKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEE-DQSIEESEDDDS 287
I +K+ + + S + S + SE D DD +EDEEEE D++ + SED
Sbjct: 612 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 671
Query: 288 DSESEAQHKSNN 299
SES ++ +S +
Sbjct: 672 SSESSSEDESED 683
Score = 38.9 bits (89), Expect = 0.055
Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 19/195 (9%)
Query: 884 KLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQ 943
+ L L +E R + K+L + K++ A + Q+ EK K+ +
Sbjct: 323 RFLESLPEEEQQRVLGEEKMLN-INKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 381
Query: 944 QEKIKRIQQIR---MEKEL-----RAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995
+EK +++Q+ R E EL R L KKK K +A A L+A+ K R +
Sbjct: 382 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREA-ALKAQSERKPGGEREE 440
Query: 996 QAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKL--------E 1047
+ L + +R ++ AR K + + LK + + K+ KL +
Sbjct: 441 RGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED 500
Query: 1048 QRRLELEMAKELKKP 1062
Q+R E E++ E++ P
Sbjct: 501 QKRYERELS-EMRAP 514
Score = 38.5 bits (88), Expect = 0.072
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 228 KIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDS 287
K++ P+ S S+S+ D E D D+ EED+E D S + + +S
Sbjct: 621 KLRGPNPKSSRTTLQSKSESEEDDEEDEDDE-----DEDEEEEDDENGDSSEDGGDSSES 675
Query: 288 DSESEAQHKSNNQ 300
SE E++ N+
Sbjct: 676 SSEDESEDGDENE 688
Score = 37.4 bits (85), Expect = 0.16
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 1279 HPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDE- 1337
+P + T + + D + D+DD+D +D+ +EDDE+ + ED EDE E
Sbjct: 626 NPKSSRTTLQSKSESEEDDEEDEDDED--EDEEEEDDENGDSSEDGGDSSESSSEDESED 683
Query: 1338 GDQAASVEELEKQIE 1352
GD+ +E E E
Sbjct: 684 GDENEEDDEDEDDDE 698
Score = 37.0 bits (84), Expect = 0.21
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
Query: 231 DKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSE 290
D++ E D ++G SS+ + SS D+ E+ +E E E+ ED+D D +
Sbjct: 644 DEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE----EDDEDEDDDED 699
Query: 291 SEAQHKSNNQ 300
+ + ++
Sbjct: 700 DDEDEDNESE 709
Score = 36.6 bits (83), Expect = 0.28
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Query: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLS 1355
+ + DD++ D S+D GD + ED+ + + + +DEDE D E+ + + E S
Sbjct: 655 EEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE--DDEDEDDDEDDDEDEDNESEGSS 712
Query: 1356 KQQS 1359
S
Sbjct: 713 SSSS 716
Score = 36.6 bits (83), Expect = 0.28
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 1295 GDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDED 1336
GD + +DD+D+D D+ DED+++E + + D D
Sbjct: 684 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 36.2 bits (82), Expect = 0.36
Identities = 15/78 (19%), Positives = 36/78 (46%)
Query: 1283 TPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAA 1342
T + + + D DD+D+D+ ++ + D E+ + + D ED DE ++
Sbjct: 632 TTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDD 691
Query: 1343 SVEELEKQIEKLSKQQSQ 1360
E+ ++ ++ +S+
Sbjct: 692 EDEDDDEDDDEDEDNESE 709
Score = 35.8 bits (81), Expect = 0.47
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGD 1339
D D +++DD+D DD D DDEDE+++ + + D + D
Sbjct: 683 DGDENEEDDEDEDDDED-DDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 34.7 bits (78), Expect = 1.0
Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 6/132 (4%)
Query: 196 SMGQTKSTSSGGGNRKCNQEQSKNQP--LDARVDKI--KDKKPRKKAMESSSNSDSDSGT 251
S Q S S +K +EQ K LD V + +D+ K+ + + S +
Sbjct: 565 SRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRG 624
Query: 252 SSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKA 311
+ SS S S+ E+DEE+ED E+ E++D ++ ++ ++ D
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE--SSSEDESE 682
Query: 312 DGQKATEKAQEK 323
DG + E +++
Sbjct: 683 DGDENEEDDEDE 694
Score = 33.1 bits (74), Expect = 3.0
Identities = 15/56 (26%), Positives = 27/56 (48%)
Query: 581 SHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESD 636
S + S E G +++ + +D ++DE+ED+E E D S S+S+
Sbjct: 672 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 727
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 73.9 bits (180), Expect = 2e-12
Identities = 33/84 (39%), Positives = 56/84 (66%), Gaps = 1/84 (1%)
Query: 601 SKDSEDSNEDEEEDDEEEDEEDDED-DESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659
S+ ED EDE+++DE+E+EEDDE+ D S+D S+S+SE ++E +E ++DD+D+D+
Sbjct: 675 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDD 734
Query: 660 DSDTEGEKTSMKLNKTTSSVKSPS 683
+ D E E + + ++SS S
Sbjct: 735 EDDDEDEDNESEGSSSSSSSSGDS 758
Score = 70.1 bits (170), Expect = 2e-11
Identities = 31/79 (39%), Positives = 48/79 (60%)
Query: 600 SSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDES 659
S +D E+ +DE+ED+EEED+E+ + E SES S ES+ EEDD+D+D DE
Sbjct: 677 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDED 736
Query: 660 DSDTEGEKTSMKLNKTTSS 678
D + E ++ + ++SS
Sbjct: 737 DDEDEDNESEGSSSSSSSS 755
Score = 65.1 bits (157), Expect = 7e-10
Identities = 33/115 (28%), Positives = 58/115 (50%), Gaps = 1/115 (0%)
Query: 568 VSNNVNPVKTQHHSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEE-DDEEEDEEDDEDD 626
+SN + +P S ++S+ +D +D +EDEEE DDE D +D D
Sbjct: 649 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 708
Query: 627 ESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKS 681
S+ S + + + + E E+EDDD+ D ++ D+++EG +S + +S S
Sbjct: 709 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDS 763
Score = 58.9 bits (141), Expect = 5e-08
Identities = 24/68 (35%), Positives = 41/68 (60%)
Query: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
D + SS+D DS+E ED+ E+ +E++EDDE +D + D + ++++EGS
Sbjct: 697 DENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSG 756
Query: 655 DQDESDSD 662
D +SDS+
Sbjct: 757 DSSDSDSN 764
Score = 55.8 bits (133), Expect = 4e-07
Identities = 25/60 (41%), Positives = 42/60 (70%), Gaps = 2/60 (3%)
Query: 593 GTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDD 652
G S+ S +SED +E+EE+D++E+D+EDD++DE D++SE S+S S + S + D +
Sbjct: 707 GDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDE--DNESEGSSSSSSSSGDSSDSDSN 764
Score = 53.1 bits (126), Expect = 3e-06
Identities = 21/79 (26%), Positives = 38/79 (48%)
Query: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDK 654
D + ++ +D N D ED + E ED+ D ++E D E D E +E++D++
Sbjct: 686 DDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNES 745
Query: 655 DQDESDSDTEGEKTSMKLN 673
+ S S + G+ + N
Sbjct: 746 EGSSSSSSSSGDSSDSDSN 764
Score = 52.8 bits (125), Expect = 4e-06
Identities = 29/91 (31%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
Query: 209 NRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDL 268
+R Q +S+++ D + +D+ ++ E+ +S+ D G SS++SSE S D D+
Sbjct: 667 SRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSE-DGGDSSESSSED-ESEDGDEN 724
Query: 269 EEDEEEEDQSIEESEDDDSDSESEAQHKSNN 299
EED+E+ED ++ ED+D++SE + S++
Sbjct: 725 EEDDEDEDDDEDDDEDEDNESEGSSSSSSSS 755
Score = 42.7 bits (99), Expect = 0.004
Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 11/108 (10%)
Query: 1236 DYMSNLRRDKWVVEGKLRKLR--IIHAKKTGKRDTSGGIDLGEEQHPLGTPTPGRKRRRK 1293
+Y+SN R+ + G K + +K + D D +E G
Sbjct: 647 EYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDG 706
Query: 1294 GGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQA 1341
G S+ +D+ + D+ +EDDEDE+D ED +DEDE +++
Sbjct: 707 GDSSESSSEDESEDGDENEEDDEDEDDDED---------DDEDEDNES 745
Score = 42.4 bits (98), Expect = 0.005
Identities = 22/65 (33%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
P P R S+ ++DD++D DD +DEDEE+++D+ G D ED + +++S
Sbjct: 662 PNPKSSRTTLQSKSESEEDDEEDEDD----EDEDEEEEDDENG---DSSEDGGDSSESSS 714
Query: 1344 VEELE 1348
+E E
Sbjct: 715 EDESE 719
Score = 41.2 bits (95), Expect = 0.011
Identities = 17/63 (26%), Positives = 32/63 (50%)
Query: 1284 PTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAAS 1343
P R + +S+ DD++D+D +D+ +E+++DE + G + EDE +
Sbjct: 664 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDE 723
Query: 1344 VEE 1346
EE
Sbjct: 724 NEE 726
Score = 40.0 bits (92), Expect = 0.025
Identities = 23/72 (31%), Positives = 37/72 (51%), Gaps = 1/72 (1%)
Query: 229 IKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEE-DQSIEESEDDDS 287
I +K+ + + S + S + SE D DD +EDEEEE D++ + SED
Sbjct: 649 ISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGD 708
Query: 288 DSESEAQHKSNN 299
SES ++ +S +
Sbjct: 709 SSESSSEDESED 720
Score = 38.9 bits (89), Expect = 0.055
Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 19/195 (9%)
Query: 884 KLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQ 943
+ L L +E R + K+L + K++ A + Q+ EK K+ +
Sbjct: 360 RFLESLPEEEQQRVLGEEKMLN-INKKQATSPASKKPAQEGGKGGSEKPKRPVSAMFIFS 418
Query: 944 QEKIKRIQQIR---MEKEL-----RAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995
+EK +++Q+ R E EL R L KKK K +A A L+A+ K R +
Sbjct: 419 EEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREA-ALKAQSERKPGGEREE 477
Query: 996 QAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKL--------E 1047
+ L + +R ++ AR K + + LK + + K+ KL +
Sbjct: 478 RGKLPESPKRAEEIWQQSVIGDYLARFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAED 537
Query: 1048 QRRLELEMAKELKKP 1062
Q+R E E++ E++ P
Sbjct: 538 QKRYERELS-EMRAP 551
Score = 38.5 bits (88), Expect = 0.072
Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 5/73 (6%)
Query: 228 KIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDS 287
K++ P+ S S+S+ D E D D+ EED+E D S + + +S
Sbjct: 658 KLRGPNPKSSRTTLQSKSESEEDDEEDEDDE-----DEDEEEEDDENGDSSEDGGDSSES 712
Query: 288 DSESEAQHKSNNQ 300
SE E++ N+
Sbjct: 713 SSEDESEDGDENE 725
Score = 37.4 bits (85), Expect = 0.16
Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 3/75 (4%)
Query: 1279 HPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDE- 1337
+P + T + + D + D+DD+D +D+ +EDDE+ + ED EDE E
Sbjct: 663 NPKSSRTTLQSKSESEEDDEEDEDDED--EDEEEEDDENGDSSEDGGDSSESSSEDESED 720
Query: 1338 GDQAASVEELEKQIE 1352
GD+ +E E E
Sbjct: 721 GDENEEDDEDEDDDE 735
Score = 37.0 bits (84), Expect = 0.21
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
Query: 231 DKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSE 290
D++ E D ++G SS+ + SS D+ E+ +E E E+ ED+D D +
Sbjct: 681 DEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENE----EDDEDEDDDED 736
Query: 291 SEAQHKSNNQ 300
+ + ++
Sbjct: 737 DDEDEDNESE 746
Score = 36.6 bits (83), Expect = 0.28
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 2/64 (3%)
Query: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLS 1355
+ + DD++ D S+D GD + ED+ + + + +DEDE D E+ + + E S
Sbjct: 692 EEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE--DDEDEDDDEDDDEDEDNESEGSS 749
Query: 1356 KQQS 1359
S
Sbjct: 750 SSSS 753
Score = 36.6 bits (83), Expect = 0.28
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 1295 GDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDED 1336
GD + +DD+D+D D+ DED+++E + + D D
Sbjct: 721 GDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762
Score = 36.2 bits (82), Expect = 0.36
Identities = 15/78 (19%), Positives = 36/78 (46%)
Query: 1283 TPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAA 1342
T + + + D DD+D+D+ ++ + D E+ + + D ED DE ++
Sbjct: 669 TTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDD 728
Query: 1343 SVEELEKQIEKLSKQQSQ 1360
E+ ++ ++ +S+
Sbjct: 729 EDEDDDEDDDEDEDNESE 746
Score = 35.8 bits (81), Expect = 0.47
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 1296 DSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGD 1339
D D +++DD+D DD D DDEDE+++ + + D + D
Sbjct: 720 DGDENEEDDEDEDDDED-DDEDEDNESEGSSSSSSSSGDSSDSD 762
Score = 34.7 bits (78), Expect = 1.0
Identities = 31/132 (23%), Positives = 57/132 (43%), Gaps = 6/132 (4%)
Query: 196 SMGQTKSTSSGGGNRKCNQEQSKNQP--LDARVDKI--KDKKPRKKAMESSSNSDSDSGT 251
S Q S S +K +EQ K LD V + +D+ K+ + + S +
Sbjct: 602 SRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRG 661
Query: 252 SSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKA 311
+ SS S S+ E+DEE+ED E+ E++D ++ ++ ++ D
Sbjct: 662 PNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSE--SSSEDESE 719
Query: 312 DGQKATEKAQEK 323
DG + E +++
Sbjct: 720 DGDENEEDDEDE 731
Score = 33.1 bits (74), Expect = 3.0
Identities = 15/56 (26%), Positives = 27/56 (48%)
Query: 581 SHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESD 636
S + S E G +++ + +D ++DE+ED+E E D S S+S+
Sbjct: 709 SSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSDSN 764
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 73.6 bits (179), Expect = 2e-12
Identities = 49/178 (27%), Positives = 81/178 (45%), Gaps = 23/178 (12%)
Query: 2004 KGKKVTLTGDTEDEDSASTSSSLKRGNKDLKKRKMEENTSINLSKQESFTSVKKPKRDD- 2062
K K V DT +++ ++S L K + + ++ +K PK+D
Sbjct: 238 KKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAK---VVARRESGGRPIKPPKKDLE 294
Query: 2063 --------------SKDLALCSMILTEMETHEDA---WPFLLPVNLKLVP--GYKKVIKK 2103
S+ L C IL EM + + A WPF PV+ + + Y +IK
Sbjct: 295 DGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKH 354
Query: 2104 PMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKKW 2161
PMD ST++ K+ +YP+ + FA DVRL+F NC +N D ++ ++ FE ++
Sbjct: 355 PMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRF 412
Score = 62.0 bits (149), Expect = 6e-09
Identities = 34/106 (32%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Query: 2057 KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVN-LKL-VPGYKKVIKKPMDFSTIREKL 2114
KP R ++ + ++++ + H+ AWPF PV+ +KL +P Y K+IK PMD TI+++L
Sbjct: 31 KPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRL 90
Query: 2115 SSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
+ Y + D +F NC +N+ DI + K F +K
Sbjct: 91 ENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQK 136
Score = 36.6 bits (83), Expect = 0.28
Identities = 33/133 (24%), Positives = 63/133 (47%), Gaps = 6/133 (4%)
Query: 905 RKLQKQEQARVAKE---AKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRA 961
R + QEQ + E A Q + ++K+++KE+ K K +EK K +++ E+E +A
Sbjct: 462 RLAELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKA 521
Query: 962 QQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEAR 1021
+ AK+ ++++A K ++ + +QA E E + + M E R
Sbjct: 522 KVAPPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEE---EEGLPMSYDEKR 578
Query: 1022 KKAEEKERLKQEK 1034
+ + + RL EK
Sbjct: 579 QLSLDINRLPGEK 591
Score = 33.1 bits (74), Expect = 3.0
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Query: 199 QTKSTSSGGGNRKCNQE----QSKNQPLDARVDKIK-----DKKPRKKAMESSSNSDSDS 249
Q K S+ G + + Q K + L+ R+ + KKP +K S+ S S
Sbjct: 641 QRKPFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPS 700
Query: 250 GTSSDTSSEGISSSDSDDLEEDEEEE 275
SS +SSE SSS S + + E
Sbjct: 701 RLSSSSSSESGSSSSSGSSSDSSDSE 726
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 73.2 bits (178), Expect = 3e-12
Identities = 55/194 (28%), Positives = 110/194 (56%), Gaps = 16/194 (8%)
Query: 888 KLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKI 947
KLQAQ + +L +L +Q++ ++ ++ +K I EEK +++E+ KI +Q+EK+
Sbjct: 268 KLQAQ-----VEENELWNRLNQQQEEKMWRQEEK---IQEREEKIQEQEE-KIREQEEKM 318
Query: 948 KRIQQIRMEKE--LRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQER 1005
+R +++ EKE +R Q+ + +K++K K+ E EK I+E+E +RQ+ ++ QE+
Sbjct: 319 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK-IREQEEKRQEEEKIREQEK 377
Query: 1006 ERRRQHMMLM---KAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKP 1062
+ ++ M K E +K E+E + QE ++EK +E K+ ++ E++ +E +
Sbjct: 378 RQEQEAKMWRQEEKIREQEEKIREQEEMMQE-QEEKMGEQEEKMWEQEEEMQEQEEKMRR 436
Query: 1063 NEDMCLADQKPLPE 1076
E+ +K + E
Sbjct: 437 QEEKIREQEKKIRE 450
Score = 68.6 bits (166), Expect = 7e-11
Identities = 46/211 (21%), Positives = 113/211 (53%), Gaps = 13/211 (6%)
Query: 878 LDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQE--QARVAKEAKKQQAIMAAEEKRKQK 935
L + AKL +++ E+ + Q + + +++E Q R K ++++ I EEK +++
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321
Query: 936 EQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQ 995
E++ + +++EK++R +++ EKE + +++ E ++++ + + E++I+E+E R++
Sbjct: 322 EEM-MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 380
Query: 996 QAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEK----------RDEKRLNKERK 1045
Q + QE + R Q + + E ++ EEK ++EK ++EK +E K
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440
Query: 1046 LEQRRLELEMAKELKKPNEDMCLADQKPLPE 1076
+ ++ ++ +E + E+M ++ + E
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMGE 471
Score = 67.8 bits (164), Expect = 1e-10
Identities = 48/217 (22%), Positives = 116/217 (53%), Gaps = 20/217 (9%)
Query: 852 DRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQE 911
++ R +EE R K R E +AK+ R Q ++I Q +I+ ++ +++
Sbjct: 357 EKIREQEEKRQEEEKIR-----EQEKRQEQEAKMWR--QEEKIREQEEKIREQEEMMQEQ 409
Query: 912 QARVAKEAKK---QQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAK 968
+ ++ ++ +K Q+ M +E++ ++++ KI +Q++KI+ E+++R Q+ + +
Sbjct: 410 EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE-----QEEKIREQEEMMQE 464
Query: 969 KKKKEEAANAKLLEAEKRIKEKEMR-RQQAVLLKHQERERRRQHMMLMKAMEARKKAEEK 1027
+++K K+ E E +++E+E + R+Q ++ QE++ R Q + + E ++ EEK
Sbjct: 465 QEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 524
Query: 1028 ERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNE 1064
+++EK +E K++++ ++ +E + E
Sbjct: 525 ----MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Score = 67.4 bits (163), Expect = 1e-10
Identities = 62/271 (22%), Positives = 134/271 (49%), Gaps = 46/271 (16%)
Query: 830 KEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKL 889
+EE + + ++ R + + + +E +MRR++ E + + K+ R
Sbjct: 286 QEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQE---------EMMWEKEEKMRR-- 334
Query: 890 QAQEIARQAAQIKLLR-KLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIK 948
Q + + + +I+ L K+ +QE+ R +E K+Q+ E++++Q+++ K+ +Q+EKI+
Sbjct: 335 QEEMMWEKEEKIRELEEKMHEQEKIR-EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR 393
Query: 949 RIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKE--MRRQQAVL------L 1000
E+++R Q+ + ++++K K+ E E+ ++E+E MRRQ+ + +
Sbjct: 394 E-----QEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Query: 1001 KHQERERRRQHMMLM-----------KAMEARKKAEEKERLKQEKRDEKRLNKERKL--- 1046
+ QE + R Q M+ K E K +E+E K +++EK +E+K+
Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE-KMRRQEEKIREQEKKIREQ 507
Query: 1047 -----EQRRLELEMAKELKKPNEDMCLADQK 1072
EQ + E +++ + E MC ++K
Sbjct: 508 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEK 538
Score = 67.0 bits (162), Expect = 2e-10
Identities = 53/187 (28%), Positives = 101/187 (54%), Gaps = 12/187 (6%)
Query: 876 EFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQK 935
E L +AKL KLQ E + Q+ + +K E+A++ ++ QA K Q
Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264
Query: 936 EQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKE--MR 993
K+ Q E+ + ++ ++E + + E K +++EE K+ E E++I+E+E MR
Sbjct: 265 VSAKLQAQVEENELWNRLNQQQEEKMWR-QEEKIQEREE----KIQEQEEKIREQEEKMR 319
Query: 994 RQQAVLLKHQERERRRQHMML---MKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRR 1050
RQ+ ++ + +E+ RR++ MM K E +K E+E+++++ +EKR +E+ EQ +
Sbjct: 320 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ--EEKRQEEEKIREQEK 377
Query: 1051 LELEMAK 1057
+ + AK
Sbjct: 378 RQEQEAK 384
Score = 62.0 bits (149), Expect = 6e-09
Identities = 52/196 (26%), Positives = 105/196 (53%), Gaps = 26/196 (13%)
Query: 888 KLQAQEIARQAAQIKLLRKLQK----QEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQ 943
K++ QE RQ + K+ R+ +K +E+ R +E ++Q E++ K EQ + M++
Sbjct: 371 KIREQE-KRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429
Query: 944 Q-EKIKRIQQ-IR--------MEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKE-- 991
Q EK++R ++ IR E+++R Q+ + ++++K K+ E E +++E+E
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 992 MRRQQAVL------LKHQERERRRQHMMLMKAMEARKKAEEK---ERLKQEKRDEKRLNK 1042
MRRQ+ + ++ QE + R Q M+ + E + EEK + K ++++EK +
Sbjct: 490 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 549
Query: 1043 ERKLEQRRLELEMAKE 1058
E K+ ++ + L +E
Sbjct: 550 EEKMREQEVRLRQQEE 565
Score = 59.7 bits (143), Expect = 3e-08
Identities = 46/216 (21%), Positives = 108/216 (50%), Gaps = 32/216 (14%)
Query: 888 KLQAQEIARQAAQIKLLRK----LQKQEQARVAKEAKKQQAIMAAEEKRKQKE------- 936
K++ QE + K+ R+ +K+E+ R +E +Q + +E+++Q+E
Sbjct: 317 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 376
Query: 937 -----QIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKE 991
+ K+ +Q+EKI+ E+++R Q+ + ++++K K+ E E+ ++E+E
Sbjct: 377 KRQEQEAKMWRQEEKIR-----EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431
Query: 992 MR-RQQAVLLKHQERERRRQHMMLMKAMEARKKAEEK----------ERLKQEKRDEKRL 1040
+ R+Q ++ QE++ R Q + + E ++ EEK + K ++++EK
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMR 491
Query: 1041 NKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPE 1076
+E K+ ++ ++ +E + E+M ++ + E
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWE 527
Score = 52.8 bits (125), Expect = 4e-06
Identities = 39/145 (26%), Positives = 86/145 (59%), Gaps = 9/145 (6%)
Query: 876 EFLDNADAKLLRKLQAQEIARQAAQIKLLR-KLQKQEQARVAKEAK--KQQAIMAAEEKR 932
E + + K+ R Q ++I Q +I+ K+++QE+ +E K +Q+ M +E +
Sbjct: 425 EEMQEQEEKMRR--QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAK 482
Query: 933 KQKEQIKIMKQQEKIKRIQQ-IR-MEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEK 990
Q+++ K+ +Q+EKI+ ++ IR E+++R Q+ + ++++K K+ E E++++E+
Sbjct: 483 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 542
Query: 991 E--MRRQQAVLLKHQERERRRQHMM 1013
E MRRQ+ + + + R R+++ M
Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKM 567
Score = 49.3 bits (116), Expect = 4e-05
Identities = 34/163 (20%), Positives = 83/163 (50%), Gaps = 30/163 (18%)
Query: 890 QAQEIARQAAQIKLLRKLQKQEQARVAKEAK---KQQAIMAAEEKRKQKEQIKIMKQQEK 946
Q +++ RQ +I+ K ++++ ++ ++ + +Q+ M +E + +++ K+ +Q+EK
Sbjct: 430 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 947 IKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMR-RQQAVLLKHQER 1005
++R ++ K+ E EK+I+E+E + R+Q +++ QE
Sbjct: 490 MRRQEE--------------------------KIREQEKKIREQEEKIREQEEMMQEQEE 523
Query: 1006 ERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLEQ 1048
+ Q + + E ++ EEK R ++EK E+ + ++ E+
Sbjct: 524 KMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 40.0 bits (92), Expect = 0.025
Identities = 32/152 (21%), Positives = 81/152 (53%), Gaps = 13/152 (8%)
Query: 852 DRQRAREESRMRRRKGR----PPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKL 907
+ + +E +MRR++ + + E +++++ + + ++ + K+
Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483
Query: 908 QKQEQARVAKEAK---KQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQI 964
Q+QE+ +E K +++ I EEK +++E++ + +Q+EK+ ++ E+E + Q+
Sbjct: 484 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM-MQEQEEKMWEQEEKMCEQEEKMQE- 541
Query: 965 LEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQ 996
E K +++EE K+ E E R++++E + Q+
Sbjct: 542 QEEKMRRQEE----KMREQEVRLRQQEEKMQE 569
Score = 38.5 bits (88), Expect = 0.072
Identities = 29/151 (19%), Positives = 74/151 (49%), Gaps = 3/151 (1%)
Query: 1306 DSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIEKLSKQQSQYRRKL 1365
+ +++ E +E +++E+K G++ + +++E Q E++ +Q EK+ +Q+ + R +
Sbjct: 394 EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE-EKMRRQEEKIREQEKKIREQE 452
Query: 1366 FDASHSLRSVMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREKL--KKAESVQ 1423
+ +++ + + + E E EE +E+EK ++ E ++
Sbjct: 453 EKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIR 512
Query: 1424 IKEEMFETSGDSLNCSNTDHCEQKEDLKEKD 1454
+EEM + + + CEQ+E ++E++
Sbjct: 513 EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 543
Score = 33.9 bits (76), Expect = 1.8
Identities = 31/150 (20%), Positives = 66/150 (44%), Gaps = 11/150 (7%)
Query: 1313 EDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEELEKQIE---KLSKQQSQYR---RKLF 1366
E +E + E+K ++ I E E++ + + E EK+ E K+ +Q+ + R K+
Sbjct: 341 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 1367 DASHSLRSVMFGQDRYRRRYWILPQCGGIFVEGMESGEGLEEIAKEREK--LKKAESVQI 1424
+ ++ + W + E E EE +E+EK ++ E ++
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEE---EMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 1425 KEEMFETSGDSLNCSNTDHCEQKEDLKEKD 1454
+EEM + + + CEQ+ ++E++
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQE 487
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 73.2 bits (178), Expect = 3e-12
Identities = 45/134 (33%), Positives = 68/134 (50%), Gaps = 20/134 (14%)
Query: 2048 KQESFTSVKKPKRDD---------------SKDLALCSMILTEMETHEDA---WPFLLPV 2089
++ES VK PK+D S+ L CS IL EM + A WPF PV
Sbjct: 321 RRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPV 380
Query: 2090 NLKLVP--GYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIG 2147
+++ + Y +IK PMD STI+ KL + +Y + + F DVRL+F NC +N D ++
Sbjct: 381 DVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVV 440
Query: 2148 RAGHNMRKYFEKKW 2161
++ FE ++
Sbjct: 441 AMARKLQDVFEMRF 454
Score = 68.2 bits (165), Expect = 9e-11
Identities = 38/106 (35%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 2057 KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVN-LKL-VPGYKKVIKKPMDFSTIREKL 2114
KPKR ++ L ++L + H+ AWPF PV+ +KL +P Y K+IK PMD TI+++L
Sbjct: 55 KPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRL 114
Query: 2115 SSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
+ Y N + D +F NC +N+ DI + K F +K
Sbjct: 115 ENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQK 160
Score = 41.6 bits (96), Expect = 0.009
Identities = 56/256 (21%), Positives = 104/256 (40%), Gaps = 38/256 (14%)
Query: 238 AMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEE-------------EEDQSIEESED 284
A SSS+S SDS + SD+S++ + L E +E + Q+ + ++
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
Query: 285 DDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIH----QPLPLASE-SQTHS 339
D + + +HK +V + S K K T+K + +P P+ S+ T+
Sbjct: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
Query: 340 FQSQQK-QPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETY 398
+ + K +P ++ ++ E + + +IQS + SL N E
Sbjct: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQS-------REPSLKNSNPDEIE 653
Query: 399 MKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQ-----AFPSQLKKQESSKSLKK 453
+ P L+ E +TS LR KR+ + A S++K SS+S
Sbjct: 654 IDFETLKPSTLR-------ELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS 706
Query: 454 VIAALSNPKATSSSPA 469
++ S+ + + + PA
Sbjct: 707 SESSSSDSEDSETGPA 722
Score = 36.2 bits (82), Expect = 0.36
Identities = 27/117 (23%), Positives = 49/117 (41%), Gaps = 6/117 (5%)
Query: 583 PAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESD 642
P +V +DS SS DS+ S +D EE+ + E E ++ Q + S + +
Sbjct: 475 PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534
Query: 643 TEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAK 699
+E+D +K +++ E E+ S K P T + N +++K
Sbjct: 535 KPKKKEKDKKEKKKEKHKRKEEVEENK------KSKAKEPPPKKTKKNNSSNSNVSK 585
Score = 34.7 bits (78), Expect = 1.0
Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 14/118 (11%)
Query: 869 PPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAA 928
PP+ ++ ++D+ +E A++ A++ QEQ + E Q A ++
Sbjct: 482 PPSSSDSSSDSSSDSDSSTDDSEEERAQRLAEL--------QEQLKAVHE---QLAALSQ 530
Query: 929 --EEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAE 984
+ K K+KE+ K K++EK KR +++ K+ +A++ KK KK ++N+ + + E
Sbjct: 531 PQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE-PPPKKTKKNNSSNSNVSKKE 587
Score = 33.1 bits (74), Expect = 3.0
Identities = 51/247 (20%), Positives = 95/247 (38%), Gaps = 13/247 (5%)
Query: 136 IPP---LFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTT 192
+PP + APP+ + DSSS S S S + E+ + + LS
Sbjct: 473 VPPPTKVVAPPSSS-DSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALS-- 529
Query: 193 ASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTS 252
+ K +K + + K + + + K K+ P+K +SSNS+
Sbjct: 530 -QPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEP 588
Query: 253 SDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKAD 312
+ S+ + +S EE+++ + S EE D K V + +P
Sbjct: 589 APMKSKPPPTYES---EEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLK 645
Query: 313 GQKATEKAQEKRIHQPLPLAS-ESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKH 371
E + +P L E S ++++PQ ++++ I SS+ K S ++
Sbjct: 646 NSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQ--AEKVDVIAGSSKMKGFSSSES 703
Query: 372 TSVIQST 378
S +S+
Sbjct: 704 ESSSESS 710
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 73.2 bits (178), Expect = 3e-12
Identities = 45/134 (33%), Positives = 68/134 (50%), Gaps = 20/134 (14%)
Query: 2048 KQESFTSVKKPKRDD---------------SKDLALCSMILTEMETHEDA---WPFLLPV 2089
++ES VK PK+D S+ L CS IL EM + A WPF PV
Sbjct: 321 RRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPV 380
Query: 2090 NLKLVP--GYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIG 2147
+++ + Y +IK PMD STI+ KL + +Y + + F DVRL+F NC +N D ++
Sbjct: 381 DVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVV 440
Query: 2148 RAGHNMRKYFEKKW 2161
++ FE ++
Sbjct: 441 AMARKLQDVFEMRF 454
Score = 68.2 bits (165), Expect = 9e-11
Identities = 38/106 (35%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Query: 2057 KPKRDDSKDLALCSMILTEMETHEDAWPFLLPVN-LKL-VPGYKKVIKKPMDFSTIREKL 2114
KPKR ++ L ++L + H+ AWPF PV+ +KL +P Y K+IK PMD TI+++L
Sbjct: 55 KPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRL 114
Query: 2115 SSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
+ Y N + D +F NC +N+ DI + K F +K
Sbjct: 115 ENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQK 160
Score = 39.3 bits (90), Expect = 0.042
Identities = 58/273 (21%), Positives = 108/273 (39%), Gaps = 45/273 (16%)
Query: 238 AMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEE-------------EEDQSIEESED 284
A SSS+S SDS + SD+S++ + L E +E + Q+ + ++
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
Query: 285 DDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIH----QPLPLASE-SQTHS 339
D + + +HK +V + S K K T+K + +P P+ S+ T+
Sbjct: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
Query: 340 FQSQQK-QPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETY 398
+ + K +P ++ ++ E + + +IQS + SL N E
Sbjct: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQS-------REPSLKNSNPDEIE 653
Query: 399 MKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQ-----AFPSQLKKQESSKSLKK 453
+ P L+ E +TS LR KR+ + A S++K SS+S
Sbjct: 654 IDFETLKPSTLR-------ELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS 706
Query: 454 VIAALSNPKAT-------SSSPAHPKQTLENNH 479
++ S+ + + S HP + + +H
Sbjct: 707 SESSSSDSEDSETEMAPKSKKKGHPGREQKKHH 739
Score = 39.3 bits (90), Expect = 0.042
Identities = 41/188 (21%), Positives = 91/188 (48%), Gaps = 16/188 (8%)
Query: 836 PRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRK---LQAQ 892
P IR E P PD+ + ++E + + + N + A L++K +
Sbjct: 1160 PVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNM----GSWASLVQKHPTTPSS 1215
Query: 893 EIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEK-RKQKEQIKIMKQQEKIKRI- 950
+ + R+ ++++ R ++A K QA A +EK R ++E+++ + ++ +++
Sbjct: 1216 TAKSSSDSFEQFRRAAREKEER--EKALKAQAEHAEKEKERLRQERMRSREDEDALEQAR 1273
Query: 951 ---QQIRMEKELRAQQILEAKKKKKEEAAN--AKLLEAEKRIKEKEMRRQQAVLLKHQER 1005
++ R +E + QQ E +++++++AA A + + + M QQ L + +E+
Sbjct: 1274 RAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQ 1333
Query: 1006 ERRRQHMM 1013
ERRR+ M
Sbjct: 1334 ERRRREAM 1341
Score = 38.9 bits (89), Expect = 0.055
Identities = 30/112 (26%), Positives = 57/112 (50%), Gaps = 8/112 (7%)
Query: 942 KQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLK 1001
+++EK + Q EKE + + ++ E+A LE +R E+ RRQ+ +
Sbjct: 1235 EEREKALKAQAEHAEKEKERLRQERMRSREDEDA-----LEQARRAHEEARRRQEQQQQQ 1289
Query: 1002 HQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKR-LNKERKLEQRRLE 1052
QE+++++Q A A +A+ + Q D++R L ++R+ E+RR E
Sbjct: 1290 RQEQQQQQQQQAAAVAAAATPQAQSSQ--PQSMLDQQRELARKREQERRRRE 1339
Score = 37.7 bits (86), Expect = 0.12
Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 11/80 (13%)
Query: 970 KKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKER 1029
++KEE A +AE KEKE RQ+ + + E A+E ++A E+ R
Sbjct: 1232 REKEEREKALKAQAEHAEKEKERLRQERMRSREDE-----------DALEQARRAHEEAR 1280
Query: 1030 LKQEKRDEKRLNKERKLEQR 1049
+QE++ ++R ++++ +Q+
Sbjct: 1281 RRQEQQQQQRQEQQQQQQQQ 1300
Score = 36.2 bits (82), Expect = 0.36
Identities = 27/117 (23%), Positives = 49/117 (41%), Gaps = 6/117 (5%)
Query: 583 PAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESD 642
P +V +DS SS DS+ S +D EE+ + E E ++ Q + S + +
Sbjct: 475 PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQN 534
Query: 643 TEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAK 699
+E+D +K +++ E E+ S K P T + N +++K
Sbjct: 535 KPKKKEKDKKEKKKEKHKRKEEVEENK------KSKAKEPPPKKTKKNNSSNSNVSK 585
Score = 35.8 bits (81), Expect = 0.47
Identities = 54/265 (20%), Positives = 102/265 (38%), Gaps = 13/265 (4%)
Query: 136 IPP---LFAPPAQNHDSSSFHSRTSGKSNRNGPEKGVNGSINGSNTSSVIGINTSVLSTT 192
+PP + APP+ + DSSS S S S + E+ + + LS
Sbjct: 473 VPPPTKVVAPPSSS-DSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALS-- 529
Query: 193 ASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTS 252
+ K +K + + K + + + K K+ P+K +SSNS+
Sbjct: 530 -QPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEP 588
Query: 253 SDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKAD 312
+ S+ + +S EE+++ + S EE D K V + +P
Sbjct: 589 APMKSKPPPTYES---EEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLK 645
Query: 313 GQKATEKAQEKRIHQPLPLAS-ESQTHSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKH 371
E + +P L E S ++++PQ ++++ I SS+ K S ++
Sbjct: 646 NSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQ--AEKVDVIAGSSKMKGFSSSES 703
Query: 372 TSVIQSTGLVSNVKPLSLVNQAKKE 396
S +S+ S + ++KK+
Sbjct: 704 ESSSESSSSDSEDSETEMAPKSKKK 728
Score = 34.7 bits (78), Expect = 1.0
Identities = 30/118 (25%), Positives = 61/118 (51%), Gaps = 14/118 (11%)
Query: 869 PPNVGNAEFLDNADAKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAA 928
PP+ ++ ++D+ +E A++ A++ QEQ + E Q A ++
Sbjct: 482 PPSSSDSSSDSSSDSDSSTDDSEEERAQRLAEL--------QEQLKAVHE---QLAALSQ 530
Query: 929 --EEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAE 984
+ K K+KE+ K K++EK KR +++ K+ +A++ KK KK ++N+ + + E
Sbjct: 531 PQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE-PPPKKTKKNNSSNSNVSKKE 587
Score = 32.7 bits (73), Expect = 4.0
Identities = 31/138 (22%), Positives = 54/138 (39%), Gaps = 13/138 (9%)
Query: 218 KNQPLDARVDKIKDKK-------PRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEE 270
+N P DK K K+ P+K + S + T+ + S SD E+
Sbjct: 1167 QNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQ 1226
Query: 271 DEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLP 330
++ E E+ + +++A+H + L + + A E+A +R H+
Sbjct: 1227 FR----RAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQA--RRAHEEAR 1280
Query: 331 LASESQTHSFQSQQKQPQ 348
E Q Q QQ+Q Q
Sbjct: 1281 RRQEQQQQQRQEQQQQQQ 1298
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 72.8 bits (177), Expect = 3e-12
Identities = 34/97 (35%), Positives = 51/97 (52%)
Query: 2064 KDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLE 2123
KD +L ++ H+ AWPFL PV+ P Y VIK+PMD +T+ E++ Y L
Sbjct: 2788 KDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLT 2847
Query: 2124 TFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
F D+ +FDNC +N DS + + +F +K
Sbjct: 2848 EFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQK 2884
Score = 56.6 bits (135), Expect = 3e-07
Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 9/96 (9%)
Query: 610 DEEEDDEEEDEED--DEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEK 667
D+ E +EEE+EED E++E +D +E +SE D E EEDDDD D E D + +
Sbjct: 127 DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDA 186
Query: 668 TSMKLNKTTSSVKSPS--MSLTGHSTPRNLHIAKAP 701
+ T SS +S S S G PR +H ++P
Sbjct: 187 SYC----TESSFRSHSTYSSTPGRRKPR-VHRPRSP 217
Score = 46.6 bits (109), Expect = 3e-04
Identities = 35/149 (23%), Positives = 62/149 (41%), Gaps = 6/149 (4%)
Query: 585 KSLVEQFRGTDSDIPSSKDSE----DSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSE 640
+ ++E R DI + K E D NE E + + E ++ +D+S + S+ + +
Sbjct: 554 EEILESIRAKKGDIDNVKSPEETEKDKNETENDSKDAEKNREEFEDQSLEKDSDDKTPDD 613
Query: 641 SDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTT--SSVKSPSMSLTGHSTPRNLHIA 698
+G EE + D+ S S G+ T+ ++ T S +SP L+ N+
Sbjct: 614 DPEQGKSEEPTEVGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEK 673
Query: 699 KAPGSAPAALCSESQSPAFLGTSSSTLTS 727
K P + E +S+T TS
Sbjct: 674 KVASELPQDVPEEPNKTCESSNTSATTTS 702
Score = 42.4 bits (98), Expect = 0.005
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 6/56 (10%)
Query: 1933 YCQICRK-GDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIA-KASGQT 1986
+C++C K GD LL C+ C H C +P + +P+ +W C C+A K G T
Sbjct: 392 HCRVCHKLGD----LLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVT 443
Score = 41.2 bits (95), Expect = 0.011
Identities = 36/171 (21%), Positives = 69/171 (40%), Gaps = 14/171 (8%)
Query: 580 HSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNS 639
H + L + RG++ ++ + E + + ++ + E+ E D +++E+DS
Sbjct: 530 HMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDS-- 587
Query: 640 ESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRNLHIAK 699
D E + EE +D + +SD T + ++ + V G+S NL
Sbjct: 588 -KDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGD-----KGNSVSANL---- 637
Query: 700 APGSAPAALCSESQSPAFLGTSSSTLTSSPHSGTSKRRRVTDERELRIPLE 750
G SE SP+ + L+ +P S ++V E +P E
Sbjct: 638 --GDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEE 686
Score = 37.4 bits (85), Expect = 0.16
Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 13/78 (16%)
Query: 264 DSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKA--- 320
+ D + E+EEEED EE++D + D E E + ++ + D D TE +
Sbjct: 137 EEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRS 196
Query: 321 ----------QEKRIHQP 328
++ R+H+P
Sbjct: 197 HSTYSSTPGRRKPRVHRP 214
Score = 37.4 bits (85), Expect = 0.16
Identities = 38/161 (23%), Positives = 65/161 (40%), Gaps = 13/161 (8%)
Query: 244 NSDSDSGTSSDTSSEGISSSDSDDLEEDEEE-EDQSIEESEDDDSDSESEAQHKSNNQVL 302
N S T D + + +DS D E++ EE EDQS+E+ DD + + Q KS
Sbjct: 569 NVKSPEETEKDKNE---TENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTE 625
Query: 303 L----HGISDPKADG--QKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPF 356
+ + +S D +E+ P+ SE+ S +++K L Q +P
Sbjct: 626 VGDKGNSVSANLGDNTTNATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVP- 684
Query: 357 IFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKET 397
+ ES N + + N S +N ++ E+
Sbjct: 685 --EEPNKTCESSNTSATTTSIQPNLENSNSSSELNSSQSES 723
Score = 37.4 bits (85), Expect = 0.16
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 589 EQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDE--SDDSQSESDSNSESDTEGS 646
+ GT +++ + D D + + + E D E DE D+ +D N ++ +
Sbjct: 1059 KSLEGTKNNMDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGADQNEMDISKIT 1118
Query: 647 EEEDDDDKDQDESDSDTEGEKTSMKLN---KTTSSVKSPSMS 685
E++D D K+ +SDSD ++ M+++ KT S V S
Sbjct: 1119 EKKDQDVKELLDSDSDKPCKEEPMEVDDDMKTESHVNCQESS 1160
Score = 35.0 bits (79), Expect = 0.80
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 264 DSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEK 323
D + EE+EEEED EE E++D D+E E Q +++ D +D + E +
Sbjct: 127 DDHESEEEEEEEDMVSEEEEEEDGDAE-ETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDD 185
Query: 324 RIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFI 357
+ T+S +++P+V + P +
Sbjct: 186 ASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPIL 219
Score = 34.7 bits (78), Expect = 1.0
Identities = 100/512 (19%), Positives = 186/512 (36%), Gaps = 94/512 (18%)
Query: 209 NRKCNQEQSKNQPLDARVDKIKDKK----PRKKAMESSSNSDSDSGTSSDTSSEGISSSD 264
N + + E +KN +D +D+ +K P+K +E S D G+ + ++ +
Sbjct: 1056 NYRKSLEGTKNN-MDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGAD----QN 1110
Query: 265 SDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKR 324
D+ + E++DQ ++E D DSD +
Sbjct: 1111 EMDISKITEKKDQDVKELLDSDSDKPCK-------------------------------- 1138
Query: 325 IHQPLPLASESQTHSFQSQQKQPQ--VLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVS 382
+P+ + + +T S + Q+ Q V++ F ++S K+ +K +++
Sbjct: 1139 -EEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLE-----R 1192
Query: 383 NVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQL 442
+K +L + + E I + G +T+ +L S + +K K+ S
Sbjct: 1193 RIKQFTLEEKQRLEK----IKLEGGIKGIGKTSTNSSKNLSESPVITKA---KEGCQSDS 1245
Query: 443 KKQESSKSL-----KKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGV 497
+QE S + + +I S ++ + P T +P + V
Sbjct: 1246 MRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPK-------------DRV 1292
Query: 498 IQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPV----MP 553
+ V +P TK Q+ I +I S S S S +T GN + +
Sbjct: 1293 LDDVSIRSP---ETKCPKQNSIENDIEEKVSDLASRGQEPSKS--KTKGNDFFIDDSKLA 1347
Query: 554 SASPI--LHSQGKEKAVSNN----VNPVKTQHHSHPAKSLVEQ-----FRGTDSDIPSSK 602
SA I L + K+ + V+ K+ HS KS ++ R D +
Sbjct: 1348 SADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGC 1407
Query: 603 DSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSD 662
DSE ++ E D ++ E+D + +ES S E E + K + S
Sbjct: 1408 DSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGES 1467
Query: 663 TEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRN 694
T + + + T ++ K PS P N
Sbjct: 1468 TGNCEDRLPVKGTEANGKKPSQQKKLEERPVN 1499
Score = 33.5 bits (75), Expect = 2.3
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 10/58 (17%)
Query: 1289 KRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEE 1346
+ + GD++ D +DD +D+ +EDD+D + E E ED+ D A+ E
Sbjct: 144 EEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPE----------EMEDDDDDASYCTE 191
Score = 33.1 bits (74), Expect = 3.0
Identities = 29/131 (22%), Positives = 58/131 (44%), Gaps = 5/131 (3%)
Query: 560 HSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTD--SDIPS--SKDSEDSNEDEEEDD 615
++ +E + S +PV + + ++ E+ ++ D+P +K E SN
Sbjct: 643 NATSEETSPSEGRSPVGCLSETPDSSNMAEKKVASELPQDVPEEPNKTCESSNTSATTTS 702
Query: 616 EEED-EEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNK 674
+ + E + E + SQSES ++ G E Q+E D + EK++ +L++
Sbjct: 703 IQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKSNGELSE 762
Query: 675 TTSSVKSPSMS 685
+ + K S S
Sbjct: 763 SPGAGKGASGS 773
Score = 32.7 bits (73), Expect = 4.0
Identities = 15/71 (21%), Positives = 38/71 (53%), Gaps = 5/71 (7%)
Query: 1281 LGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDED-----EEDKEDKKGKKTDICEDE 1335
L T R+ K D++ +++++ +D E++E+ EE ++ + ++ ++ ED+
Sbjct: 111 LARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDD 170
Query: 1336 DEGDQAASVEE 1346
D+ D +E+
Sbjct: 171 DDSDYPEEMED 181
Score = 32.7 bits (73), Expect = 4.0
Identities = 51/241 (21%), Positives = 88/241 (36%), Gaps = 31/241 (12%)
Query: 5 ERLPSSAASSTTPTSSSTPSVASVVSK-------GGLSTGVASLSSTI--NPCGHLFRTA 55
++ P+ A+STT +SST S S K G ++TG + +T +P F+
Sbjct: 2048 QQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQN 2107
Query: 56 GDQPFNLST------VSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLAS 109
+ +T +S V V G+ +S+G S+ + P +
Sbjct: 2108 KNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSG 2167
Query: 110 FPGAEWWRTTDAHTRTGATFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGV 169
G T+++ TG P + + P Q RT P++ +
Sbjct: 2168 SGGT----TSNSQVITGPQIRPGM----TVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVM 2219
Query: 170 NGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKI 229
I G S+ + +V ST S+ STS N + S +QP + ++
Sbjct: 2220 TQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTS--------NIQSSASQPPRPQQGQV 2271
Query: 230 K 230
K
Sbjct: 2272 K 2272
Score = 32.3 bits (72), Expect = 5.2
Identities = 49/242 (20%), Positives = 97/242 (40%), Gaps = 47/242 (19%)
Query: 836 PRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIA 895
P++ A + R + S+ R R P + + + Q Q
Sbjct: 2449 PQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQ-----------QSQVQTTT 2497
Query: 896 RQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRM 955
Q I+ LQ Q + + + A E KQK+ + +++E + I ++
Sbjct: 2498 SQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQV 2557
Query: 956 EKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLM 1015
K IL+ K++++AA K+ +R+++V K ++ + +L
Sbjct: 2558 MK-----YILDKIDKEEKQAA-------------KKRKREESVEQKRSKQNATKLSALLF 2599
Query: 1016 KAMEARKKAEEKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLP 1075
K KE+L+ E + K+R L + L++E+ +ELK+ D+ + +K L
Sbjct: 2600 K---------HKEQLRAE------ILKKRALLDKDLQIEVQEELKR---DLKIKKEKDLM 2641
Query: 1076 EL 1077
+L
Sbjct: 2642 QL 2643
Score = 32.0 bits (71), Expect = 6.8
Identities = 56/255 (21%), Positives = 101/255 (39%), Gaps = 41/255 (16%)
Query: 495 NGVIQSVIQEAPLALTTKTKMQS-KINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMP 553
+G+++ I++ L K +++ K+ I T +S NLS S PV+
Sbjct: 1187 DGLLERRIKQ--FTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSES---------PVIT 1235
Query: 554 SASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDI-----PSSKDSEDSN 608
A S + S N N + + L++ +DS + PS ++
Sbjct: 1236 KAKEGCQSDSMRQEQSPNAN-------NDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYP 1288
Query: 609 EDEEEDD-----------EEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQD 657
+D DD ++ E+D +++ D S S+S T+G++ DD K
Sbjct: 1289 KDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLAS 1348
Query: 658 ESDSDTEGEKTSMKL-NKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPA-----ALCSE 711
D T K L + + ++ S S S S P++ + A + A L +
Sbjct: 1349 ADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCD 1408
Query: 712 SQSPAFLGTSSSTLT 726
S+S + L SS T++
Sbjct: 1409 SESNSTLENSSDTVS 1423
Score = 32.0 bits (71), Expect = 6.8
Identities = 68/340 (20%), Positives = 125/340 (36%), Gaps = 54/340 (15%)
Query: 161 NRNGPEKGVNGS---INGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQS 217
NR +KG S ING + I + L + S + SG K N
Sbjct: 1518 NRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRV------VSGNVEPKVNNINK 1571
Query: 218 KNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQ 277
D + +K+ R D + SS+T S +SSSD++ D E
Sbjct: 1572 IIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLP 1631
Query: 278 SIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQ- 336
S +ES+ + + S + +SN+ + + ++ +K T P+ SE +
Sbjct: 1632 STKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSS----------PITSEEES 1681
Query: 337 --THSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAK 394
++ F + P ++ + + ++K ++V + + ST + + K + V +
Sbjct: 1682 NLSNDFIDENGLPINKNENV-----NGESKRKTVITEVTTMTST-VATESKTVIKVEKGD 1735
Query: 395 KETYM-------------------KLIVPSP----DVLKAGNKNTSEESSLLTSELRSKR 431
K+T + KL PS D++ ++ + ++ +T L +
Sbjct: 1736 KQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTG 1795
Query: 432 EQYKQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHP 471
S +E S K + S PK T S A P
Sbjct: 1796 ---GTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALP 1832
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 72.8 bits (177), Expect = 3e-12
Identities = 34/97 (35%), Positives = 51/97 (52%)
Query: 2064 KDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVIKKPMDFSTIREKLSSGQYPNLE 2123
KD +L ++ H+ AWPFL PV+ P Y VIK+PMD +T+ E++ Y L
Sbjct: 2805 KDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLT 2864
Query: 2124 TFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
F D+ +FDNC +N DS + + +F +K
Sbjct: 2865 EFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQK 2901
Score = 56.6 bits (135), Expect = 3e-07
Identities = 36/96 (37%), Positives = 51/96 (53%), Gaps = 9/96 (9%)
Query: 610 DEEEDDEEEDEED--DEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEK 667
D+ E +EEE+EED E++E +D +E +SE D E EEDDDD D E D + +
Sbjct: 127 DDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDA 186
Query: 668 TSMKLNKTTSSVKSPS--MSLTGHSTPRNLHIAKAP 701
+ T SS +S S S G PR +H ++P
Sbjct: 187 SYC----TESSFRSHSTYSSTPGRRKPR-VHRPRSP 217
Score = 51.2 bits (121), Expect = 1e-05
Identities = 50/223 (22%), Positives = 107/223 (47%), Gaps = 48/223 (21%)
Query: 900 QIKLLRKLQKQ-------EQARVAKEAKKQQAIMAAEEKRKQKEQIKIM------KQQEK 946
Q+++L ++Q Q +Q+ V ++ K Q I + Q QI+ + QE+
Sbjct: 2441 QVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQ 2500
Query: 947 IKRIQQIRMEKELRAQQILEAKKKKKEEAAN-AKLLEAEKRIKEK---EMRRQQAVLLKH 1002
++R+QQ+R +++ + QQ +E K++ +A+N +++++ + +K E +Q+ +
Sbjct: 2501 LQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPA 2560
Query: 1003 QERERRRQHM--MLMKAMEARKKAEEKERLKQEKRDEK---------------------- 1038
+ E +R + +MK + + EEK+ K+ KR+E
Sbjct: 2561 EREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKE 2620
Query: 1039 ----RLNKERKLEQRRLELEMAKELKKPNEDMCLADQKPLPEL 1077
+ K+R L + L++E+ +ELK+ D+ + +K L +L
Sbjct: 2621 QLRAEILKKRALLDKDLQIEVQEELKR---DLKIKKEKDLMQL 2660
Score = 42.4 bits (98), Expect = 0.005
Identities = 20/56 (35%), Positives = 30/56 (53%), Gaps = 6/56 (10%)
Query: 1933 YCQICRK-GDNEELLLLCDGCDKGCHTYCHRPKITTIPDGDWFCPACIA-KASGQT 1986
+C++C K GD LL C+ C H C +P + +P+ +W C C+A K G T
Sbjct: 392 HCRVCHKLGD----LLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVT 443
Score = 40.0 bits (92), Expect = 0.025
Identities = 31/143 (21%), Positives = 61/143 (42%), Gaps = 6/143 (4%)
Query: 580 HSHPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDS-- 637
H + L + RG++ ++ + E + + ++ + E+ E D +++E+DS
Sbjct: 530 HMDITEDLTNKARGSNKSFLAAANEEILESIRAKKGDIDNVKSPEETEKDKNETENDSKD 589
Query: 638 ---NSESDTEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSV-KSPSMSLTGHSTPR 693
N E + S E+D DDK D+ + E K K+ + +SP + R
Sbjct: 590 AEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEVGDFKSEKSNGELSESPGAGKGASGSTR 649
Query: 694 NLHIAKAPGSAPAALCSESQSPA 716
+ + P S + L S+ + A
Sbjct: 650 IITRLRNPDSKLSQLKSQQVAAA 672
Score = 38.9 bits (89), Expect = 0.055
Identities = 99/501 (19%), Positives = 176/501 (35%), Gaps = 94/501 (18%)
Query: 244 NSDSDSGTSSDTSSEGISSSDSDDLEEDEEE-EDQSIEESEDDDSDSESEAQHKSNNQVL 302
N S T D + + +DS D E++ EE EDQS+E+ DD + + Q KS
Sbjct: 569 NVKSPEETEKDKNE---TENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSE---- 621
Query: 303 LHGISDPKADGQKATEKAQEKRIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFIFQSSQ 362
+ K++G+ + K ++ T K Q+ SQQ+ +
Sbjct: 622 VGDFKSEKSNGELSESPGAGKGASG----STRIITRLRNPDSKLSQLKSQQVAAAAHEAN 677
Query: 363 AKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSL 422
K K V+ S G +S + KKE MK + + L K +
Sbjct: 678 -KLFKEGKEVLVVNSQGEISRL-------STKKEVIMKGNINNYFKLGQEGKYRVYHNQY 729
Query: 423 LTSELRSKREQYKQ-------------AFPSQLKKQESSKSLKKVIAALSNPKATSSSPA 469
T+ + Q+++ P+ K S KV+ +S + T +
Sbjct: 730 STNSFALNKHQHREDHDKRRHLAHKFCLTPAGEFKWNGSVHGSKVL-TISTLRLTITQ-- 786
Query: 470 HPKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSKINENIAAASST 529
LENN P+ FL PN + + +K + + + A
Sbjct: 787 -----LENNIPSSFL--------HPNWASHRANWIKAVQMCSKPREFALALAILECAVKP 833
Query: 530 PFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLV- 588
P+ + G T + + + K++ + ++ P K V
Sbjct: 834 VVMLPIWRESLGHTRLHRMTSIEREEKEKVKKKEKKQEEEETMQQATWVKYTFPVKHQVW 893
Query: 589 ----EQFRGT----------------------DSDIPSSKDSEDSNEDEEEDDEEED--- 619
E++R T ++++ K E + + +E+ +E D
Sbjct: 894 KQKGEEYRVTGYGGWSWISKTHVYRFVPKLPGNTNVNYRKSLEGTKNNMDENMDESDKRK 953
Query: 620 ----------EEDDEDDE--SDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSDTEGEK 667
E D E DE D+ +D N ++ +E++D D K+ +SDSD ++
Sbjct: 954 CSRSPKKIKIEPDSEKDEVKGSDAAKGADQNEMDISKITEKKDQDVKELLDSDSDKPCKE 1013
Query: 668 TSMKLN---KTTSSVKSPSMS 685
M+++ KT S V S
Sbjct: 1014 EPMEVDDDMKTESHVNCQESS 1034
Score = 37.4 bits (85), Expect = 0.16
Identities = 20/78 (25%), Positives = 35/78 (44%), Gaps = 13/78 (16%)
Query: 264 DSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKA--- 320
+ D + E+EEEED EE++D + D E E + ++ + D D TE +
Sbjct: 137 EEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDDASYCTESSFRS 196
Query: 321 ----------QEKRIHQP 328
++ R+H+P
Sbjct: 197 HSTYSSTPGRRKPRVHRP 214
Score = 35.0 bits (79), Expect = 0.80
Identities = 24/94 (25%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Query: 264 DSDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEK 323
D + EE+EEEED EE E++D D+E E Q +++ D +D + E +
Sbjct: 127 DDHESEEEEEEEDMVSEEEEEEDGDAE-ETQDSEDDEEDEMEEDDDDSDYPEEMEDDDDD 185
Query: 324 RIHQPLPLASESQTHSFQSQQKQPQVLSQQLPFI 357
+ T+S +++P+V + P +
Sbjct: 186 ASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPIL 219
Score = 34.7 bits (78), Expect = 1.0
Identities = 100/512 (19%), Positives = 186/512 (36%), Gaps = 94/512 (18%)
Query: 209 NRKCNQEQSKNQPLDARVDKIKDKK----PRKKAMESSSNSDSDSGTSSDTSSEGISSSD 264
N + + E +KN +D +D+ +K P+K +E S D G+ + ++ +
Sbjct: 930 NYRKSLEGTKNN-MDENMDESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKGAD----QN 984
Query: 265 SDDLEEDEEEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKR 324
D+ + E++DQ ++E D DSD +
Sbjct: 985 EMDISKITEKKDQDVKELLDSDSDKPCK-------------------------------- 1012
Query: 325 IHQPLPLASESQTHSFQSQQKQPQ--VLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVS 382
+P+ + + +T S + Q+ Q V++ F ++S K+ +K +++
Sbjct: 1013 -EEPMEVDDDMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKKTKSSKLDGLLE-----R 1066
Query: 383 NVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQL 442
+K +L + + E I + G +T+ +L S + +K K+ S
Sbjct: 1067 RIKQFTLEEKQRLEK----IKLEGGIKGIGKTSTNSSKNLSESPVITKA---KEGCQSDS 1119
Query: 443 KKQESSKSL-----KKVIAALSNPKATSSSPAHPKQTLENNHPNPFLTNALLGNHQPNGV 497
+QE S + + +I S ++ + P T +P + V
Sbjct: 1120 MRQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYPK-------------DRV 1166
Query: 498 IQSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPV----MP 553
+ V +P TK Q+ I +I S S S S +T GN + +
Sbjct: 1167 LDDVSIRSP---ETKCPKQNSIENDIEEKVSDLASRGQEPSKS--KTKGNDFFIDDSKLA 1221
Query: 554 SASPI--LHSQGKEKAVSNN----VNPVKTQHHSHPAKSLVEQ-----FRGTDSDIPSSK 602
SA I L + K+ + V+ K+ HS KS ++ R D +
Sbjct: 1222 SADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGC 1281
Query: 603 DSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQDESDSD 662
DSE ++ E D ++ E+D + +ES S E E + K + S
Sbjct: 1282 DSESNSTLENSSDTVSIQDSSEEDMIVQNSNESISEQFRTREQDVEVLEPLKCELVSGES 1341
Query: 663 TEGEKTSMKLNKTTSSVKSPSMSLTGHSTPRN 694
T + + + T ++ K PS P N
Sbjct: 1342 TGNCEDRLPVKGTEANGKKPSQQKKLEERPVN 1373
Score = 33.5 bits (75), Expect = 2.3
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 10/58 (17%)
Query: 1289 KRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDEDEGDQAASVEE 1346
+ + GD++ D +DD +D+ +EDD+D + E E ED+ D A+ E
Sbjct: 144 EEEEEDGDAEETQDSEDDEEDEMEEDDDDSDYPE----------EMEDDDDDASYCTE 191
Score = 32.7 bits (73), Expect = 4.0
Identities = 15/71 (21%), Positives = 38/71 (53%), Gaps = 5/71 (7%)
Query: 1281 LGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDED-----EEDKEDKKGKKTDICEDE 1335
L T R+ K D++ +++++ +D E++E+ EE ++ + ++ ++ ED+
Sbjct: 111 LARTTAARRAVNKVVYDDHESEEEEEEEDMVSEEEEEEDGDAEETQDSEDDEEDEMEEDD 170
Query: 1336 DEGDQAASVEE 1346
D+ D +E+
Sbjct: 171 DDSDYPEEMED 181
Score = 32.7 bits (73), Expect = 4.0
Identities = 51/241 (21%), Positives = 88/241 (36%), Gaps = 31/241 (12%)
Query: 5 ERLPSSAASSTTPTSSSTPSVASVVSK-------GGLSTGVASLSSTI--NPCGHLFRTA 55
++ P+ A+STT +SST S S K G ++TG + +T +P F+
Sbjct: 1922 QQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQN 1981
Query: 56 GDQPFNLST------VSSAFPMVSHPVFGLHSASSGHSEFGGLGTLGTPTALAAHPQLAS 109
+ +T +S V V G+ +S+G S+ + P +
Sbjct: 1982 KNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSG 2041
Query: 110 FPGAEWWRTTDAHTRTGATFFPPLLGIPPLFAPPAQNHDSSSFHSRTSGKSNRNGPEKGV 169
G T+++ TG P + + P Q RT P++ +
Sbjct: 2042 SGGT----TSNSQVITGPQIRPGM----TVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVM 2093
Query: 170 NGSINGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQSKNQPLDARVDKI 229
I G S+ + +V ST S+ STS N + S +QP + ++
Sbjct: 2094 TQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTS--------NIQSSASQPPRPQQGQV 2145
Query: 230 K 230
K
Sbjct: 2146 K 2146
Score = 32.0 bits (71), Expect = 6.8
Identities = 56/255 (21%), Positives = 101/255 (39%), Gaps = 41/255 (16%)
Query: 495 NGVIQSVIQEAPLALTTKTKMQS-KINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMP 553
+G+++ I++ L K +++ K+ I T +S NLS S PV+
Sbjct: 1061 DGLLERRIKQ--FTLEEKQRLEKIKLEGGIKGIGKTSTNSSKNLSES---------PVIT 1109
Query: 554 SASPILHSQGKEKAVSNNVNPVKTQHHSHPAKSLVEQFRGTDSDI-----PSSKDSEDSN 608
A S + S N N + + L++ +DS + PS ++
Sbjct: 1110 KAKEGCQSDSMRQEQSPNAN-------NDQPEDLIQGCSESDSSVLRMSDPSHTTNKLYP 1162
Query: 609 EDEEEDD-----------EEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDDDKDQD 657
+D DD ++ E+D +++ D S S+S T+G++ DD K
Sbjct: 1163 KDRVLDDVSIRSPETKCPKQNSIENDIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKLAS 1222
Query: 658 ESDSDTEGEKTSMKL-NKTTSSVKSPSMSLTGHSTPRNLHIAKAPGSAPA-----ALCSE 711
D T K L + + ++ S S S S P++ + A + A L +
Sbjct: 1223 ADDIGTLICKNKKPLIQEESDTIVSSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLGCD 1282
Query: 712 SQSPAFLGTSSSTLT 726
S+S + L SS T++
Sbjct: 1283 SESNSTLENSSDTVS 1297
Score = 32.0 bits (71), Expect = 6.8
Identities = 68/340 (20%), Positives = 125/340 (36%), Gaps = 54/340 (15%)
Query: 161 NRNGPEKGVNGS---INGSNTSSVIGINTSVLSTTASSSMGQTKSTSSGGGNRKCNQEQS 217
NR +KG S ING + I + L + S + SG K N
Sbjct: 1392 NRESEKKGQRTSTFQINGKDNKPKIYLKGECLKEISESRV------VSGNVEPKVNNINK 1445
Query: 218 KNQPLDARVDKIKDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQ 277
D + +K+ R D + SS+T S +SSSD++ D E
Sbjct: 1446 IIPENDIKSLTVKESAIRPFINGDVIMEDFNERNSSETKSHLLSSSDAEGNYRDSLETLP 1505
Query: 278 SIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQ- 336
S +ES+ + + S + +SN+ + + ++ +K T P+ SE +
Sbjct: 1506 STKESDSTQTTTPSASCPESNSVNQVEDMEIETSEVKKVTSS----------PITSEEES 1555
Query: 337 --THSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAK 394
++ F + P ++ + + ++K ++V + + ST + + K + V +
Sbjct: 1556 NLSNDFIDENGLPINKNENV-----NGESKRKTVITEVTTMTST-VATESKTVIKVEKGD 1609
Query: 395 KETYM-------------------KLIVPSP----DVLKAGNKNTSEESSLLTSELRSKR 431
K+T + KL PS D++ ++ + ++ +T L +
Sbjct: 1610 KQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSKTVVTTTVTDSLTTTG 1669
Query: 432 EQYKQAFPSQLKKQESSKSLKKVIAALSNPKATSSSPAHP 471
S +E S K + S PK T S A P
Sbjct: 1670 ---GTLVTSMTVSKEYSTRDKVKLMKFSRPKKTRSGTALP 1706
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 72.8 bits (177), Expect = 3e-12
Identities = 55/199 (27%), Positives = 91/199 (45%), Gaps = 22/199 (11%)
Query: 1976 PACIAKASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKK 2035
P+ K S L + V+G N S + G D+ + ++S + + +
Sbjct: 178 PSVFPKTSISPLNV----VQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSP 233
Query: 2036 RKMEENTSI-----NLSK------QESFTSVKKPKRDDSKDLALCSMILTEMETHED--- 2081
E++ ++ N+ K Q+ + VK K ++ L CS IL EM +
Sbjct: 234 TFTEKSVALPPIKENMPKNVLPDSQQQYNVVKTVKV--TEQLRHCSEILKEMLAKKHFSY 291
Query: 2082 AWPFLLPVNLKLVP--GYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETF 2139
AWPF PV++ + Y V+K PMD TI+EK+ + +Y + FA DVRL+F NC +
Sbjct: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
Query: 2140 NEDDSDIGRAGHNMRKYFE 2158
N D ++ ++ FE
Sbjct: 352 NPPDHEVVTMARMLQDVFE 370
Score = 58.5 bits (140), Expect = 7e-08
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 2052 FTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVN-LKL-VPGYKKVIKKPMDFST 2109
+ + KK R ++ L ++L ++ H +WPF PV+ +KL +P Y +IK PMD +T
Sbjct: 19 YINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNT 78
Query: 2110 IREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
I+++L + Y D +F NC +N+ DI + K F +K
Sbjct: 79 IKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQK 129
Score = 43.9 bits (102), Expect = 0.002
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 219 NQPLDARVDKIK-DKKPRKKAME-----SSSNSDSDSGTSSDTSSEGISSSDSDDLEEDE 272
N L++R + K DK KA+E S S+S S S + S++SS +SSSDS D E
Sbjct: 610 NNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSD---SE 666
Query: 273 EEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQ--KATEKAQEKRIHQPLP 330
E E + +DS S+ + N +L G + G + T A +HQ P
Sbjct: 667 SEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTLVHQTTP 726
Score = 37.0 bits (84), Expect = 0.21
Identities = 55/245 (22%), Positives = 97/245 (39%), Gaps = 36/245 (14%)
Query: 218 KNQPLDARVDKIKDK-KPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEED 276
K Q L+ R+ + ++ RK+ +S S + + SE SSS S E E
Sbjct: 598 KKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSS-----SSESES 652
Query: 277 QSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQ 336
S + S D SDSESE K ++ K + + E ++ + LP E +
Sbjct: 653 SSSDLSSSDSSDSESEMFPK---------FTEVKPNDSPSKENVKKMKNECILP---EGR 700
Query: 337 THSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKE 396
T Q S + Q++ + N H L N + L + K
Sbjct: 701 TGVTQIGYCVQDTTSANTTLVHQTTPSHVMPPNHHQ-------LAFNYQELEHLQTVKNI 753
Query: 397 TYMKLIVPSPDVLKAGNKNT------SEESSLLTSELRSKREQYKQAFPSQLKKQESSKS 450
+ ++++ PS D + N T ++++L SE ++ ++ ++K +S KS
Sbjct: 754 SPLQILPPSGDSEQLSNGITVMHPSGDSDTTMLESECQAPVQK-----DIKIKNADSWKS 808
Query: 451 LKKVI 455
L K +
Sbjct: 809 LGKPV 813
Score = 35.4 bits (80), Expect = 0.61
Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 25/112 (22%)
Query: 933 KQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANA-----KLLEAEKRI 987
K +EQ+K + QQ ++ + Q+ K L ++ K+KKKE+ N+ K+ E + R+
Sbjct: 425 KLQEQLKAVHQQLQV--LSQVPFRK-LNKKKEKSKKEKKKEKVNNSNENPRKMCE-QMRL 480
Query: 988 KEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKR 1039
KEK R +Q ++R++Q + L K+E+++ K DEKR
Sbjct: 481 KEKSKR--------NQPKKRKQQFIGL--------KSEDEDNAKPMNYDEKR 516
Score = 35.0 bits (79), Expect = 0.80
Identities = 71/329 (21%), Positives = 127/329 (38%), Gaps = 48/329 (14%)
Query: 352 QQLPFIFQSSQAKEESVNKHTSVIQSTGLVSN------VKPLSLVNQAKKETYMKLIVPS 405
+ +P + + E + ++T+ S G S+ VK L+ + + K + +L V S
Sbjct: 382 ESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLS 441
Query: 406 PDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQESSK-----SLKKVIAALSN 460
+ NK + E + + + Q++ +E SK K+ L +
Sbjct: 442 QVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKS 501
Query: 461 PKATSSSPAH--PKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSK 518
++ P + K+ L N N L G+ G + +IQ +L+ + +
Sbjct: 502 EDEDNAKPMNYDEKRQLSLN------INKLPGDKL--GRVVHIIQSREPSLSNSNPDEIE 553
Query: 519 IN-ENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEKA------VSNN 571
I+ E + A++ V+ R +M S LHSQ K++ V+N
Sbjct: 554 IDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEE-LHSQKKQELEKRLLDVNNQ 612
Query: 572 VNPVKTQHHS---HPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDES 628
+N K Q S P+K++ R ++S SS SE E D S
Sbjct: 613 LNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSES-------------ESSSSDLSS 659
Query: 629 DDSQSESDSNSESDTEGSEEEDDDDKDQD 657
DS SDS SE + +E + +D ++
Sbjct: 660 SDS---SDSESEMFPKFTEVKPNDSPSKE 685
Score = 33.5 bits (75), Expect = 2.3
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 9/93 (9%)
Query: 883 AKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMK 942
AKL +L+A Q RKL K+++ + KE KK++ + E RK EQ M+
Sbjct: 424 AKLQEQLKAVHQQLQVLSQVPFRKLNKKKE-KSKKEKKKEKVNNSNENPRKMCEQ---MR 479
Query: 943 QQEKIKRIQQIRMEKELRAQQILEAKKKKKEEA 975
+EK KR Q + R QQ + K + ++ A
Sbjct: 480 LKEKSKRNQ-----PKKRKQQFIGLKSEDEDNA 507
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 72.8 bits (177), Expect = 3e-12
Identities = 55/199 (27%), Positives = 91/199 (45%), Gaps = 22/199 (11%)
Query: 1976 PACIAKASGQTLKIKKLHVKGKKTNESKKGKKVTLTGDTEDEDSASTSSSLKRGNKDLKK 2035
P+ K S L + V+G N S + G D+ + ++S + + +
Sbjct: 178 PSVFPKTSISPLNV----VQGASVNSSSQTAAQVTKGVKRKADTTTPATSAVKASSEFSP 233
Query: 2036 RKMEENTSI-----NLSK------QESFTSVKKPKRDDSKDLALCSMILTEMETHED--- 2081
E++ ++ N+ K Q+ + VK K ++ L CS IL EM +
Sbjct: 234 TFTEKSVALPPIKENMPKNVLPDSQQQYNVVKTVKV--TEQLRHCSEILKEMLAKKHFSY 291
Query: 2082 AWPFLLPVNLKLVP--GYKKVIKKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETF 2139
AWPF PV++ + Y V+K PMD TI+EK+ + +Y + FA DVRL+F NC +
Sbjct: 292 AWPFYNPVDVNALGLHNYYDVVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKY 351
Query: 2140 NEDDSDIGRAGHNMRKYFE 2158
N D ++ ++ FE
Sbjct: 352 NPPDHEVVTMARMLQDVFE 370
Score = 58.5 bits (140), Expect = 7e-08
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 2052 FTSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVN-LKL-VPGYKKVIKKPMDFST 2109
+ + KK R ++ L ++L ++ H +WPF PV+ +KL +P Y +IK PMD +T
Sbjct: 19 YINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQLPDYYTIIKNPMDLNT 78
Query: 2110 IREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGHNMRKYFEKK 2160
I+++L + Y D +F NC +N+ DI + K F +K
Sbjct: 79 IKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALEKLFMQK 129
Score = 43.9 bits (102), Expect = 0.002
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 219 NQPLDARVDKIK-DKKPRKKAME-----SSSNSDSDSGTSSDTSSEGISSSDSDDLEEDE 272
N L++R + K DK KA+E S S+S S S + S++SS +SSSDS D E
Sbjct: 610 NNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSESESSSSDLSSSDSSD---SE 666
Query: 273 EEEDQSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQ--KATEKAQEKRIHQPLP 330
E E + +DS S+ + N +L G + G + T A +HQ P
Sbjct: 667 SEMFPKFTEVKPNDSPSKENVKKMKNECILPEGRTGVTQIGYCVQDTTSANTTLVHQTTP 726
Score = 37.0 bits (84), Expect = 0.21
Identities = 55/245 (22%), Positives = 97/245 (39%), Gaps = 36/245 (14%)
Query: 218 KNQPLDARVDKIKDK-KPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEED 276
K Q L+ R+ + ++ RK+ +S S + + SE SSS S E E
Sbjct: 598 KKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSS-----SSESES 652
Query: 277 QSIEESEDDDSDSESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQPLPLASESQ 336
S + S D SDSESE K ++ K + + E ++ + LP E +
Sbjct: 653 SSSDLSSSDSSDSESEMFPK---------FTEVKPNDSPSKENVKKMKNECILP---EGR 700
Query: 337 THSFQSQQKQPQVLSQQLPFIFQSSQAKEESVNKHTSVIQSTGLVSNVKPLSLVNQAKKE 396
T Q S + Q++ + N H L N + L + K
Sbjct: 701 TGVTQIGYCVQDTTSANTTLVHQTTPSHVMPPNHHQ-------LAFNYQELEHLQTVKNI 753
Query: 397 TYMKLIVPSPDVLKAGNKNT------SEESSLLTSELRSKREQYKQAFPSQLKKQESSKS 450
+ ++++ PS D + N T ++++L SE ++ ++ ++K +S KS
Sbjct: 754 SPLQILPPSGDSEQLSNGITVMHPSGDSDTTMLESECQAPVQK-----DIKIKNADSWKS 808
Query: 451 LKKVI 455
L K +
Sbjct: 809 LGKPV 813
Score = 35.4 bits (80), Expect = 0.61
Identities = 33/112 (29%), Positives = 58/112 (51%), Gaps = 25/112 (22%)
Query: 933 KQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANA-----KLLEAEKRI 987
K +EQ+K + QQ ++ + Q+ K L ++ K+KKKE+ N+ K+ E + R+
Sbjct: 425 KLQEQLKAVHQQLQV--LSQVPFRK-LNKKKEKSKKEKKKEKVNNSNENPRKMCE-QMRL 480
Query: 988 KEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKR 1039
KEK R +Q ++R++Q + L K+E+++ K DEKR
Sbjct: 481 KEKSKR--------NQPKKRKQQFIGL--------KSEDEDNAKPMNYDEKR 516
Score = 35.0 bits (79), Expect = 0.80
Identities = 71/329 (21%), Positives = 127/329 (38%), Gaps = 48/329 (14%)
Query: 352 QQLPFIFQSSQAKEESVNKHTSVIQSTGLVSN------VKPLSLVNQAKKETYMKLIVPS 405
+ +P + + E + ++T+ S G S+ VK L+ + + K + +L V S
Sbjct: 382 ESMPLCYIKTDITETTGRENTNEASSEGNSSDDSEDERVKRLAKLQEQLKAVHQQLQVLS 441
Query: 406 PDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPSQLKKQESSK-----SLKKVIAALSN 460
+ NK + E + + + Q++ +E SK K+ L +
Sbjct: 442 QVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKSKRNQPKKRKQQFIGLKS 501
Query: 461 PKATSSSPAH--PKQTLENNHPNPFLTNALLGNHQPNGVIQSVIQEAPLALTTKTKMQSK 518
++ P + K+ L N N L G+ G + +IQ +L+ + +
Sbjct: 502 EDEDNAKPMNYDEKRQLSLN------INKLPGDKL--GRVVHIIQSREPSLSNSNPDEIE 553
Query: 519 IN-ENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPILHSQGKEKA------VSNN 571
I+ E + A++ V+ R +M S LHSQ K++ V+N
Sbjct: 554 IDFETLKASTLRELEKYVSACLRKRPLKPPAKKIMMSKEE-LHSQKKQELEKRLLDVNNQ 612
Query: 572 VNPVKTQHHS---HPAKSLVEQFRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDES 628
+N K Q S P+K++ R ++S SS SE E D S
Sbjct: 613 LNSRKRQTKSDKTQPSKAVENVSRLSESSSSSSSSSES-------------ESSSSDLSS 659
Query: 629 DDSQSESDSNSESDTEGSEEEDDDDKDQD 657
DS SDS SE + +E + +D ++
Sbjct: 660 SDS---SDSESEMFPKFTEVKPNDSPSKE 685
Score = 33.5 bits (75), Expect = 2.3
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 9/93 (9%)
Query: 883 AKLLRKLQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMK 942
AKL +L+A Q RKL K+++ + KE KK++ + E RK EQ M+
Sbjct: 424 AKLQEQLKAVHQQLQVLSQVPFRKLNKKKE-KSKKEKKKEKVNNSNENPRKMCEQ---MR 479
Query: 943 QQEKIKRIQQIRMEKELRAQQILEAKKKKKEEA 975
+EK KR Q + R QQ + K + ++ A
Sbjct: 480 LKEKSKRNQ-----PKKRKQQFIGLKSEDEDNA 507
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 72.4 bits (176), Expect = 5e-12
Identities = 59/183 (32%), Positives = 108/183 (59%), Gaps = 27/183 (14%)
Query: 904 LRKLQKQEQARVAK-EAKKQQAIMAA---EEKRKQKEQIKIMKQQEKIKRIQQIRMEKEL 959
L +LQ+ E+A+ AK E ++++A M A EE+RK++E+++ +QQE+I R QQ E+E
Sbjct: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR--RQQEEILRRQQ---EEER 771
Query: 960 RAQQILEAKKKKKEEAANAKLLE--AEKRIKEKEMRRQQAVLL------KHQERERRRQH 1011
+ ++ E ++K+EEA + + A +R +E+E R+QQ L + +E ERR+Q
Sbjct: 772 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 831
Query: 1012 MMLMKAME-----ARKKAE-----EKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKK 1061
+L K E AR++ E E+ RL+ E+ + ++E + +++ LE++ KEL +
Sbjct: 832 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 891
Query: 1062 PNE 1064
+
Sbjct: 892 QRQ 894
Score = 67.4 bits (163), Expect = 1e-10
Identities = 57/240 (23%), Positives = 129/240 (53%), Gaps = 48/240 (20%)
Query: 879 DNADAKLLRKLQAQEIARQAA----QIKLLRKLQKQEQARVAKEA----KKQQAIMAAEE 930
+ +A++ K + +E RQ Q ++LR+ Q++E+ R +E K+++A+ E
Sbjct: 734 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 793
Query: 931 K----RKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAAN--AKLLEAE 984
+ R+Q+E+ + +Q+E ++R+++ R E+E R +Q E +K++EEAA + EA+
Sbjct: 794 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE-ELLRKQEEEAAKWAREEEEAQ 852
Query: 985 KRIKEKEMR-RQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKE----RLKQEKRDEK- 1038
+R++E +R ++A L+H+E ER+R+ + + + E ++ ++++ RL+Q+++ ++
Sbjct: 853 RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQL 912
Query: 1039 --------------------------RLNKERKLEQRRLELEMAKELKKPNEDMCLADQK 1072
L + +KLE+ R E ++ +E ++ ++ A Q+
Sbjct: 913 AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER-ERQLREEQRRQQRELMKALQQ 971
Score = 62.8 bits (151), Expect = 4e-09
Identities = 55/261 (21%), Positives = 126/261 (48%), Gaps = 34/261 (13%)
Query: 829 LKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRK 888
L++E +RA R + +R +EE R+++ E + LR+
Sbjct: 731 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 790
Query: 889 LQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIK 948
+ QEIA LR+ +++E+ + +EA ++ EE+ ++K++ + KQ+E+
Sbjct: 791 QREQEIA--------LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAA 842
Query: 949 RIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVL--------- 999
+ + E+E +++ E + + +EEAA + E E++ KE E++RQ+ ++
Sbjct: 843 KWAR---EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 899
Query: 1000 LKHQERERRRQHMMLMK--------------AMEARKKAEEKERLKQEKRDEKRLNKERK 1045
L+ ++++++Q + MK A +++ E K E+ E++L +E++
Sbjct: 900 LRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQR 959
Query: 1046 LEQRRLELEMAKELKKPNEDM 1066
+QR L + ++ ++ + +
Sbjct: 960 RQQRELMKALQQQQQQQQQKL 980
Score = 56.2 bits (134), Expect = 3e-07
Identities = 56/243 (23%), Positives = 118/243 (48%), Gaps = 31/243 (12%)
Query: 830 KEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKL 889
K+E+ + R R E R + ++ +EE+ R + R E +LLRK
Sbjct: 783 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR-----REEEERRKQEELLRK- 836
Query: 890 QAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKE-----QIKIMKQ- 943
Q +E A+ A + + ++ ++ + R+ +EA + + EE+RK+KE Q ++M+Q
Sbjct: 837 QEEEAAKWAREEEEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELEVQRQKELMRQR 893
Query: 944 ---QEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANA-------------KLLEAEKRI 987
QE ++R+QQ + +++L ++ + ++ A KL E +R
Sbjct: 894 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 953
Query: 988 KEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLE 1047
+E RRQQ L+K ++++++Q L K + + L + +++E R ++++ +
Sbjct: 954 LREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQ 1013
Query: 1048 QRR 1050
Q++
Sbjct: 1014 QQQ 1016
Score = 45.1 bits (105), Expect = 8e-04
Identities = 45/177 (25%), Positives = 84/177 (47%), Gaps = 18/177 (10%)
Query: 841 MEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQ 900
ME R + + +R R+E ++R+K + + LR+LQ Q+ +Q AQ
Sbjct: 862 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ-------EALRRLQQQQQQQQLAQ 914
Query: 901 IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR 960
+KL +Q+ A + QA ++ E +K +E+ + ++E+ R QQ + K L+
Sbjct: 915 MKLPSSSTWGQQSNTT--ACQSQATLSLAEIQKLEEERERQLREEQ--RRQQRELMKALQ 970
Query: 961 AQQILEAKKKK------KEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQH 1011
QQ + +K K LLE ++ + ++M++QQ +HQ+ R R +
Sbjct: 971 QQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE-EARQMQKQQQQQQQHQQPNRARNN 1026
Score = 42.4 bits (98), Expect = 0.005
Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Query: 981 LEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRL 1040
LE K K ++ RR+ + K +E ER+RQ + + E ++ +E+ER ++R+E+ L
Sbjct: 723 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER---KRREEEEL 779
Query: 1041 NKERKLEQRRLELEMAKELKKPNED 1065
+ ++ E R + E L++ E+
Sbjct: 780 ARRKQEEALRRQREQEIALRRQREE 804
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 72.4 bits (176), Expect = 5e-12
Identities = 59/183 (32%), Positives = 108/183 (59%), Gaps = 27/183 (14%)
Query: 904 LRKLQKQEQARVAK-EAKKQQAIMAA---EEKRKQKEQIKIMKQQEKIKRIQQIRMEKEL 959
L +LQ+ E+A+ AK E ++++A M A EE+RK++E+++ +QQE+I R QQ E+E
Sbjct: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELR--RQQEEILRRQQ---EEER 798
Query: 960 RAQQILEAKKKKKEEAANAKLLE--AEKRIKEKEMRRQQAVLLKH------QERERRRQH 1011
+ ++ E ++K+EEA + + A +R +E+E R+QQ L+ +E ERR+Q
Sbjct: 799 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 858
Query: 1012 MMLMKAME-----ARKKAE-----EKERLKQEKRDEKRLNKERKLEQRRLELEMAKELKK 1061
+L K E AR++ E E+ RL+ E+ + ++E + +++ LE++ KEL +
Sbjct: 859 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMR 918
Query: 1062 PNE 1064
+
Sbjct: 919 QRQ 921
Score = 67.4 bits (163), Expect = 1e-10
Identities = 57/240 (23%), Positives = 129/240 (53%), Gaps = 48/240 (20%)
Query: 879 DNADAKLLRKLQAQEIARQAA----QIKLLRKLQKQEQARVAKEA----KKQQAIMAAEE 930
+ +A++ K + +E RQ Q ++LR+ Q++E+ R +E K+++A+ E
Sbjct: 761 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 820
Query: 931 K----RKQKEQIKIMKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAAN--AKLLEAE 984
+ R+Q+E+ + +Q+E ++R+++ R E+E R +Q E +K++EEAA + EA+
Sbjct: 821 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE-ELLRKQEEEAAKWAREEEEAQ 879
Query: 985 KRIKEKEMR-RQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKE----RLKQEKRDEK- 1038
+R++E +R ++A L+H+E ER+R+ + + + E ++ ++++ RL+Q+++ ++
Sbjct: 880 RRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQL 939
Query: 1039 --------------------------RLNKERKLEQRRLELEMAKELKKPNEDMCLADQK 1072
L + +KLE+ R E ++ +E ++ ++ A Q+
Sbjct: 940 AQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER-ERQLREEQRRQQRELMKALQQ 998
Score = 62.8 bits (151), Expect = 4e-09
Identities = 55/261 (21%), Positives = 126/261 (48%), Gaps = 34/261 (13%)
Query: 829 LKEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRK 888
L++E +RA R + +R +EE R+++ E + LR+
Sbjct: 758 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 817
Query: 889 LQAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIK 948
+ QEIA LR+ +++E+ + +EA ++ EE+ ++K++ + KQ+E+
Sbjct: 818 QREQEIA--------LRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAA 869
Query: 949 RIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVL--------- 999
+ + E+E +++ E + + +EEAA + E E++ KE E++RQ+ ++
Sbjct: 870 KWAR---EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEA 926
Query: 1000 LKHQERERRRQHMMLMK--------------AMEARKKAEEKERLKQEKRDEKRLNKERK 1045
L+ ++++++Q + MK A +++ E K E+ E++L +E++
Sbjct: 927 LRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQR 986
Query: 1046 LEQRRLELEMAKELKKPNEDM 1066
+QR L + ++ ++ + +
Sbjct: 987 RQQRELMKALQQQQQQQQQKL 1007
Score = 56.2 bits (134), Expect = 3e-07
Identities = 56/243 (23%), Positives = 118/243 (48%), Gaps = 31/243 (12%)
Query: 830 KEEDVIPRIRAMEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKL 889
K+E+ + R R E R + ++ +EE+ R + R E +LLRK
Sbjct: 810 KQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR-----REEEERRKQEELLRK- 863
Query: 890 QAQEIARQAAQIKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKE-----QIKIMKQ- 943
Q +E A+ A + + ++ ++ + R+ +EA + + EE+RK+KE Q ++M+Q
Sbjct: 864 QEEEAAKWAREEEEAQRRLEENRLRMEEEAAR---LRHEEEERKRKELEVQRQKELMRQR 920
Query: 944 ---QEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANA-------------KLLEAEKRI 987
QE ++R+QQ + +++L ++ + ++ A KL E +R
Sbjct: 921 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQ 980
Query: 988 KEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRLNKERKLE 1047
+E RRQQ L+K ++++++Q L K + + L + +++E R ++++ +
Sbjct: 981 LREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQ 1040
Query: 1048 QRR 1050
Q++
Sbjct: 1041 QQQ 1043
Score = 45.1 bits (105), Expect = 8e-04
Identities = 45/177 (25%), Positives = 84/177 (47%), Gaps = 18/177 (10%)
Query: 841 MEGRRGRPPNPDRQRAREESRMRRRKGRPPNVGNAEFLDNADAKLLRKLQAQEIARQAAQ 900
ME R + + +R R+E ++R+K + + LR+LQ Q+ +Q AQ
Sbjct: 889 MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQ-------EALRRLQQQQQQQQLAQ 941
Query: 901 IKLLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELR 960
+KL +Q+ A + QA ++ E +K +E+ + ++E+ R QQ + K L+
Sbjct: 942 MKLPSSSTWGQQSNTT--ACQSQATLSLAEIQKLEEERERQLREEQ--RRQQRELMKALQ 997
Query: 961 AQQILEAKKKK------KEEAANAKLLEAEKRIKEKEMRRQQAVLLKHQERERRRQH 1011
QQ + +K K LLE ++ + ++M++QQ +HQ+ R R +
Sbjct: 998 QQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQE-EARQMQKQQQQQQQHQQPNRARNN 1053
Score = 42.4 bits (98), Expect = 0.005
Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 3/85 (3%)
Query: 981 LEAEKRIKEKEMRRQQAVLLKHQERERRRQHMMLMKAMEARKKAEEKERLKQEKRDEKRL 1040
LE K K ++ RR+ + K +E ER+RQ + + E ++ +E+ER ++R+E+ L
Sbjct: 750 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEER---KRREEEEL 806
Query: 1041 NKERKLEQRRLELEMAKELKKPNED 1065
+ ++ E R + E L++ E+
Sbjct: 807 ARRKQEEALRRQREQEIALRRQREE 831
Score = 31.6 bits (70), Expect = 8.8
Identities = 22/99 (22%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 591 FRGTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDE----SDDSQSESDSNSE----SD 642
FR D S NE+ +E D+ +E ++ D S+++ S S++ SD
Sbjct: 347 FRPVDEGEECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVASEETPQTSSSSARPGTPSD 406
Query: 643 TEGSEEEDDDDKDQDESDSDTEGEKTSMKLNKTTSSVKS 681
+ E + KD+ +++ + E+ + N + V S
Sbjct: 407 HQSQEASQFERKDEPKTEQTEKAEEETRMENSLPAKVPS 445
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,405,416
Number of Sequences: 37866
Number of extensions: 4540595
Number of successful extensions: 119706
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1261
Number of HSP's successfully gapped in prelim test: 1588
Number of HSP's that attempted gapping in prelim test: 33498
Number of HSP's gapped (non-prelim): 44723
length of query: 2168
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2050
effective length of database: 13,779,330
effective search space: 28247626500
effective search space used: 28247626500
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.