Guide to the Human Genome
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Search of human proteins with 94536864

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94536864 hypothetical protein LOC138724 isoform D [Homo
sapiens]
         (1031 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94536864 hypothetical protein LOC138724 isoform D [Homo sapiens]  2138   0.0  
gi|94681096 hypothetical protein LOC138724 isoform A [Homo sapiens]  2131   0.0  
gi|94536862 hypothetical protein LOC138724 isoform C [Homo sapiens]  2075   0.0  
gi|94536860 hypothetical protein LOC138724 isoform B [Homo sapiens]  2073   0.0  
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        60   1e-08
gi|213512168 hypothetical protein LOC259308 [Homo sapiens]             52   2e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    52   2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   4e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   5e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    51   5e-06
gi|155029550 chromosome 9 open reading frame 79 [Homo sapiens]         50   1e-05
gi|148612857 sickle tail isoform 3 [Homo sapiens]                      49   3e-05
gi|148612813 sickle tail isoform 2 [Homo sapiens]                      49   3e-05
gi|41281612 zinc finger protein 828 [Homo sapiens]                     46   2e-04
gi|91206406 hypothetical protein LOC642265 [Homo sapiens]              46   2e-04
gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          46   2e-04
gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          46   2e-04
gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]          46   2e-04
gi|146231958 hypothetical protein LOC647060 [Homo sapiens]             46   2e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         45   4e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    45   5e-04
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    44   8e-04
gi|55953110 retinoblastoma protein-binding zinc finger protein i...    43   0.002
gi|20336260 retinoblastoma protein-binding zinc finger protein i...    43   0.002
gi|20336258 retinoblastoma protein-binding zinc finger protein i...    43   0.002
gi|169174618 PREDICTED: family with sequence similarity 75, memb...    42   0.002
gi|239743732 PREDICTED: family with sequence similarity 75, memb...    42   0.002
gi|153791826 hypothetical protein LOC26165 [Homo sapiens]              42   0.002
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       42   0.002
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       42   0.002

>gi|94536864 hypothetical protein LOC138724 isoform D [Homo sapiens]
          Length = 1031

 Score = 2138 bits (5540), Expect = 0.0
 Identities = 1031/1031 (100%), Positives = 1031/1031 (100%)

Query: 1    MLRKIQRWWQLGRLRQLHPWCSGNMVQGKELPLLHRVAFLDHLCKQKSEVEEEGEEEEEG 60
            MLRKIQRWWQLGRLRQLHPWCSGNMVQGKELPLLHRVAFLDHLCKQKSEVEEEGEEEEEG
Sbjct: 1    MLRKIQRWWQLGRLRQLHPWCSGNMVQGKELPLLHRVAFLDHLCKQKSEVEEEGEEEEEG 60

Query: 61   EDEASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFP 120
            EDEASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFP
Sbjct: 61   EDEASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFP 120

Query: 121  IFQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSV 180
            IFQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSV
Sbjct: 121  IFQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSV 180

Query: 181  FFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHL 240
            FFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHL
Sbjct: 181  FFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHL 240

Query: 241  RPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPA 300
            RPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPA
Sbjct: 241  RPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPA 300

Query: 301  SLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPS 360
            SLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPS
Sbjct: 301  SLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPS 360

Query: 361  RYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADP 420
            RYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADP
Sbjct: 361  RYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADP 420

Query: 421  VSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPH 480
            VSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPH
Sbjct: 421  VSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPH 480

Query: 481  RINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARC 540
            RINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARC
Sbjct: 481  RINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARC 540

Query: 541  GDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPS 600
            GDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPS
Sbjct: 541  GDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPS 600

Query: 601  SNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRN 660
            SNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRN
Sbjct: 601  SNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRN 660

Query: 661  VQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWT 720
            VQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWT
Sbjct: 661  VQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWT 720

Query: 721  VPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSC 780
            VPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSC
Sbjct: 721  VPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSC 780

Query: 781  PPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGE 840
            PPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGE
Sbjct: 781  PPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGE 840

Query: 841  KMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHP 900
            KMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHP
Sbjct: 841  KMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHP 900

Query: 901  RKPKAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTALPQLL 960
            RKPKAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTALPQLL
Sbjct: 901  RKPKAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTALPQLL 960

Query: 961  LPKASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYLSFPTLKASLTRGLQKVLAKCLD 1020
            LPKASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYLSFPTLKASLTRGLQKVLAKCLD
Sbjct: 961  LPKASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYLSFPTLKASLTRGLQKVLAKCLD 1020

Query: 1021 NHRPLPTKSSQ 1031
            NHRPLPTKSSQ
Sbjct: 1021 NHRPLPTKSSQ 1031


>gi|94681096 hypothetical protein LOC138724 isoform A [Homo sapiens]
          Length = 1079

 Score = 2131 bits (5522), Expect = 0.0
 Identities = 1027/1028 (99%), Positives = 1028/1028 (100%)

Query: 4    KIQRWWQLGRLRQLHPWCSGNMVQGKELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDE 63
            +IQRWWQLGRLRQLHPWCSGNMVQGKELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDE
Sbjct: 52   QIQRWWQLGRLRQLHPWCSGNMVQGKELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDE 111

Query: 64   ASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQ 123
            ASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQ
Sbjct: 112  ASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQ 171

Query: 124  ILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFN 183
            ILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFN
Sbjct: 172  ILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFN 231

Query: 184  KLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPF 243
            KLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPF
Sbjct: 232  KLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPF 291

Query: 244  PVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLS 303
            PVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLS
Sbjct: 292  PVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLS 351

Query: 304  EPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYK 363
            EPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYK
Sbjct: 352  EPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYK 411

Query: 364  PQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSP 423
            PQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSP
Sbjct: 412  PQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSP 471

Query: 424  PSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRIN 483
            PSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRIN
Sbjct: 472  PSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRIN 531

Query: 484  PGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARCGDI 543
            PGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARCGDI
Sbjct: 532  PGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARCGDI 591

Query: 544  QKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNS 603
            QKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNS
Sbjct: 592  QKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNS 651

Query: 604  VSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQ 663
            VSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQ
Sbjct: 652  VSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQ 711

Query: 664  REVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPE 723
            REVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPE
Sbjct: 712  REVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPE 771

Query: 724  LLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQ 783
            LLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQ
Sbjct: 772  LLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQ 831

Query: 784  QIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMK 843
            QIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMK
Sbjct: 832  QIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMK 891

Query: 844  GKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKP 903
            GKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKP
Sbjct: 892  GKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKP 951

Query: 904  KAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPK 963
            KAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPK
Sbjct: 952  KAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPK 1011

Query: 964  ASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHR 1023
            ASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHR
Sbjct: 1012 ASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHR 1071

Query: 1024 PLPTKSSQ 1031
            PLPTKSSQ
Sbjct: 1072 PLPTKSSQ 1079


>gi|94536862 hypothetical protein LOC138724 isoform C [Homo sapiens]
          Length = 1006

 Score = 2075 bits (5376), Expect = 0.0
 Identities = 1003/1003 (100%), Positives = 1003/1003 (100%)

Query: 29   KELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAP 88
            KELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAP
Sbjct: 4    KELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAP 63

Query: 89   PQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLF 148
            PQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLF
Sbjct: 64   PQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLF 123

Query: 149  WGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHG 208
            WGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHG
Sbjct: 124  WGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHG 183

Query: 209  AHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEV 268
            AHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEV
Sbjct: 184  AHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEV 243

Query: 269  LPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYRE 328
            LPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYRE
Sbjct: 244  LPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYRE 303

Query: 329  KPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPE 388
            KPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPE
Sbjct: 304  KPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPE 363

Query: 389  LSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKA 448
            LSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKA
Sbjct: 364  LSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKA 423

Query: 449  LWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASR 508
            LWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASR
Sbjct: 424  LWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASR 483

Query: 509  SPSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASP 568
            SPSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASP
Sbjct: 484  SPSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASP 543

Query: 569  LGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQ 628
            LGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQ
Sbjct: 544  LGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQ 603

Query: 629  RKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLA 688
            RKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLA
Sbjct: 604  RKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLA 663

Query: 689  EAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQ 748
            EAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQ
Sbjct: 664  EAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQ 723

Query: 749  SPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQ 808
            SPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQ
Sbjct: 724  SPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQ 783

Query: 809  PVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSP 868
            PVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSP
Sbjct: 784  PVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSP 843

Query: 869  GPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQ 928
            GPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQ
Sbjct: 844  GPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQ 903

Query: 929  ARSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKH 988
            ARSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKH
Sbjct: 904  ARSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKH 963

Query: 989  CPWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHRPLPTKSSQ 1031
            CPWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHRPLPTKSSQ
Sbjct: 964  CPWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHRPLPTKSSQ 1006


>gi|94536860 hypothetical protein LOC138724 isoform B [Homo sapiens]
          Length = 1044

 Score = 2073 bits (5371), Expect = 0.0
 Identities = 1002/1002 (100%), Positives = 1002/1002 (100%)

Query: 30   ELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAPP 89
            ELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAPP
Sbjct: 43   ELPLLHRVAFLDHLCKQKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAPP 102

Query: 90   QPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLFW 149
            QPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLFW
Sbjct: 103  QPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLFW 162

Query: 150  GLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGA 209
            GLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGA
Sbjct: 163  GLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGA 222

Query: 210  HTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVL 269
            HTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVL
Sbjct: 223  HTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVL 282

Query: 270  PGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREK 329
            PGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREK
Sbjct: 283  PGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREK 342

Query: 330  PQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPEL 389
            PQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPEL
Sbjct: 343  PQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPEL 402

Query: 390  SGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKAL 449
            SGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKAL
Sbjct: 403  SGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKAL 462

Query: 450  WETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRS 509
            WETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRS
Sbjct: 463  WETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRS 522

Query: 510  PSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPL 569
            PSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPL
Sbjct: 523  PSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPL 582

Query: 570  GVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQR 629
            GVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQR
Sbjct: 583  GVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQR 642

Query: 630  KNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAE 689
            KNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAE
Sbjct: 643  KNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAE 702

Query: 690  AVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQS 749
            AVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQS
Sbjct: 703  AVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQS 762

Query: 750  PASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQP 809
            PASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQP
Sbjct: 763  PASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQP 822

Query: 810  VQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPG 869
            VQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPG
Sbjct: 823  VQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPG 882

Query: 870  PGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQA 929
            PGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQA
Sbjct: 883  PGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQA 942

Query: 930  RSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKHC 989
            RSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKHC
Sbjct: 943  RSLVEAPVSTFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKHC 1002

Query: 990  PWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHRPLPTKSSQ 1031
            PWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHRPLPTKSSQ
Sbjct: 1003 PWAHMEKYLSFPTLKASLTRGLQKVLAKCLDNHRPLPTKSSQ 1044


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 160/750 (21%), Positives = 250/750 (33%), Gaps = 114/750 (15%)

Query: 261  PGTSPLEVLPGYETHLETTGHKKMPQAFEP----PMPPPCQSPASLSEPRKVSPEGGLAI 316
            P TS    +    T   T G K       P    P  P  Q   S  +P    P      
Sbjct: 1211 PSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPT----- 1265

Query: 317  SKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLW 376
               +  T G + +     SS+  P P + + PEL+  +S + P   KP      +  N+ 
Sbjct: 1266 ---YQATRGRKNR-----SSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMS 1317

Query: 377  AFESP--VLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLES 434
            + ++P  V+   PEL  ++    P   +   +  +SR N+    +P S  ++P  P L  
Sbjct: 1318 SVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPES--TVPIAPELPP 1375

Query: 435  LVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEAT 494
                 Q V  E  +   T G+K     S    P    P    +EP      +   T E T
Sbjct: 1376 STSTEQPVTPEPTSR-ATRGRKNR---SSGKTPETLVPTAPKLEPS--TSTDQPVTPEPT 1429

Query: 495  WKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARCG--DIQKTKNSWAS 552
             + T    N S+ ++P   +   P L P     + +     S+A  G  D    K     
Sbjct: 1430 SQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETV 1489

Query: 553  KHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVP--VFPGRGSSPSSNSVSKSHVS 610
               A  L        P+     S++  G   +     P  V P       S S  +    
Sbjct: 1490 VPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTP 1549

Query: 611  EPIADQSNYKPDGEAVEQRKN--HWATEL-PAPSSLSTPLPEPHIDLELVWRNVQQREVP 667
            EP +  +  + +  +V+  ++    A EL P+ S      PEP         N    + P
Sbjct: 1550 EPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTP 1609

Query: 668  QGPSPLAVDPLHP--------VPQPPTLAEAVKIERTHPGLPKGV--TCPGVKAEAPLSQ 717
            +   P A +P HP         P+  + A   K  R+    PK V      ++   P  Q
Sbjct: 1610 EPVVPTAPEP-HPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQ 1668

Query: 718  RWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSS--TIPDFW 775
              T PE +   G            + K LR S     P P+     SP+ +     P+  
Sbjct: 1669 SVT-PEAIAQGG------------QSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPI 1715

Query: 776  GLPSCPPQQIYPPNP---------CPHSSSCHPQ---------------EVQRTVPQPVQ 811
              PSC  +Q    NP          P S+   P+               E    +P+P  
Sbjct: 1716 TQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPAS 1775

Query: 812  SSHCHHFQSSSQLQPQE-SGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGP 870
                     +SQ+Q  E +GR+    +   K        + +     H +       P  
Sbjct: 1776 PQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQK------QPQR 1829

Query: 871  GEPSNSKVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQAR 930
            GE S   V++  + +D A       K E    PK G  +R  A                 
Sbjct: 1830 GEVSQKTVIIKEEEEDTAEKPG---KEEDVVTPKPGKRKRDQA----------------- 1869

Query: 931  SLVEAPVSTFPQRSQHRGQSSQHTALPQLL 960
               E   +  P RS  R + +Q +  P++L
Sbjct: 1870 ---EEEPNRIPSRSLRRTKLNQESTAPKVL 1896



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 137/646 (21%), Positives = 229/646 (35%), Gaps = 79/646 (12%)

Query: 237  LLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKM-PQAFEPPMPPP 295
            LL+ +  P +    +  AE  ++    SP   LP           K +  Q+ +   PPP
Sbjct: 1006 LLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPP 1065

Query: 296  CQSPASLS----------EPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLD 345
              SP   S          +  + +PE  L+   + +     + K +  +SS   P P   
Sbjct: 1066 LLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHP---KPKIRTRKSSRMTPFPATS 1122

Query: 346  SLPELQRESSLEDPSRYKPQWECRENSGNLWAFESP------VLDLNPELSGTSPECVPP 399
            + PE    +S   P   KP  +   +  N  + ++P        +L P  S   P    P
Sbjct: 1123 AAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEP 1182

Query: 400  ASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENL 459
             S+   +G +SR ++  P + V P +L   P   +     + V SE  +   T G+K N 
Sbjct: 1183 TSQVT-RGRKSRSSVKTP-ETVVPTALELQPSTST----DRPVTSEPTS-QATRGRK-NR 1234

Query: 460  WASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPPA 519
             +  +P+PV  T P          P     TSE T++ T   +N S+ ++P   +   P 
Sbjct: 1235 SSVKTPEPVVPTAPELQPSTSTDQP----VTSEPTYQATRGRKNRSSVKTPEPVVPTAPE 1290

Query: 520  LAPELLRVRSMGVLSDSEARCGDIQ----KTKNSWASKHPACNLPQDLH---GASPLGVL 572
            L P     R +     S            KT  +     P   +           P    
Sbjct: 1291 LRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRT 1350

Query: 573  SDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKN- 631
            + S++ +  ++  E+ VP+ P     P S S  +    EP +  +  + +  + +  +  
Sbjct: 1351 TRSRTNMSSVKNPESTVPIAP---ELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETL 1407

Query: 632  -HWATELPAPSSLSTPL-PEPHIDLELVWRNVQQREVPQGPSPLAVDPLHP--------V 681
               A +L   +S   P+ PEP         N    + P+   P A + L P         
Sbjct: 1408 VPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPE-LQPSTSTDQPVT 1466

Query: 682  PQPPTLAEAVKIERTHPGLPKGV--TCPGVKAEAPLSQRWT------------------V 721
            P+P + A   + +R+    P+ V  T P ++A A   Q  T                   
Sbjct: 1467 PEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEPTSRTTRGRKNRSSVKT 1526

Query: 722  PELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGL-PSC 780
            PE +  P     Q S       + +   P SRA     +  S     S +P    L PS 
Sbjct: 1527 PETVV-PAAPELQPSTSTD---QPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPST 1582

Query: 781  PPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQP 826
               Q+  P P   ++ C         P+PV  +      ++S  QP
Sbjct: 1583 SRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQP 1628



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 97/511 (18%), Positives = 176/511 (34%), Gaps = 85/511 (16%)

Query: 514  LSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPLGVLS 573
            L+PPP L+P L  ++              ++KT+   + + P   L  +L    P   + 
Sbjct: 1061 LAPPPLLSPLLPSIKPT------------VRKTRQDGSQEAPEAPLSSELEPFHPKPKIR 1108

Query: 574  DSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHW 633
                      +K + +  FP   ++P      + H S   A     KP  +A   R N  
Sbjct: 1109 T---------RKSSRMTPFPATSAAP------EPHPSTSTAQPVTPKPTSQATRSRTNRS 1153

Query: 634  ATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQG--------------PSPLAVDPL- 678
            + + P P   + P  +P    +    +    +V +G              P+ L + P  
Sbjct: 1154 SVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPST 1213

Query: 679  ---HPVPQPPTLAEAVK-------IERTHPGLPKGVTC-PGVKAEAPLSQRWTVPELLTH 727
                PV   PT ++A +       ++   P +P      P    + P++   T       
Sbjct: 1214 STDRPVTSEPT-SQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGR 1272

Query: 728  PGIHAWQWSRELKLRLKKLRQSPASRAP----GPSQSFCSSPILSSTIPDFWGLPSCPPQ 783
                + +    +     +LR S ++  P      S++  S   +SS       +P+ P  
Sbjct: 1273 KNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPEL 1332

Query: 784  QI-----YPPNPCPHSSSCHPQEVQRTVPQ-----PVQSSHCHHFQSSSQLQPQESGRAE 833
            QI      P  P P S +   +    +V       P+         +   + P+ + RA 
Sbjct: 1333 QISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRAT 1392

Query: 834  QGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDY-LSPGP------GEPSNSKVLVSGKRKD 886
            +G  R  +  GK    +    P +      D  ++P P      G  + S V        
Sbjct: 1393 RG--RKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVP 1450

Query: 887  KASASSSAKKREHPRKPKAGDH--RRGTARLGL---STVTGKNHPAQARSLVEAPVSTFP 941
             A     +   + P  P+      R  T R  +    TV       QA +  + PV++ P
Sbjct: 1451 TAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPELQASASTDQPVTSEP 1510

Query: 942  QRSQHRGQSSQHTA-LPQLLLPKASGPQDQP 971
                 RG+ ++ +   P+ ++P A  P+ QP
Sbjct: 1511 TSRTTRGRKNRSSVKTPETVVPAA--PELQP 1539


>gi|213512168 hypothetical protein LOC259308 [Homo sapiens]
          Length = 1335

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 55/192 (28%), Positives = 75/192 (39%), Gaps = 30/192 (15%)

Query: 787  PPN--PCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKG 844
            PP+  P P+    H +E      + VQ +     QS+S+  PQ S  +        K+  
Sbjct: 947  PPDTLPAPNPEGVHLKEQLANDLKAVQQNQK---QSNSKAVPQGSAHSVS------KISQ 997

Query: 845  KMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHPRKPK 904
                   +  PCV +EA V+   P   EP   +     K KD A     A  RE P + K
Sbjct: 998  PSGDMTEAHMPCVQVEANVN--KPSLEEPCGPEPQSPSKSKDPAHVPMLAGNREDPEETK 1055

Query: 905  AG-DHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFP----------QRSQHRGQSSQH 953
            A  DHR G A  G S+   +  PA+     + P    P           RS H     QH
Sbjct: 1056 AARDHREGDAGFGRSSTREERRPAED----QRPAGMLPNKTPRGSWRWSRSFHLADPCQH 1111

Query: 954  TAL--PQLLLPK 963
            +    PQL LP+
Sbjct: 1112 SPQHHPQLKLPQ 1123



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 29/64 (45%), Positives = 39/64 (60%), Gaps = 7/64 (10%)

Query: 136 SGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPL----KWSVCSSVFFNKLAF---L 188
           SG+  QQ+ SQLF GLPSLHSESL A F+ S G   +    K  +     FN+L+F   L
Sbjct: 421 SGSDLQQKYSQLFCGLPSLHSESLVATFMGSQGLPKIENVPKPPLKDPFLFNELSFPQLL 480

Query: 189 PRSN 192
           P+++
Sbjct: 481 PKTS 484


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 209/982 (21%), Positives = 306/982 (31%), Gaps = 192/982 (19%)

Query: 68   PLKPCSPTKE---APTGEQATPAPPQPSCGSE-GLLKAIGIPEQTVMQPVSPSRSFPIFQ 123
            P   C+P      AP   ++ P+P  P  G+  G  K  GI   + + PV+ S       
Sbjct: 714  PQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPK----- 768

Query: 124  ILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEA------IFLSSGGPSPLKWSVC 177
                 P     AS     +         PS    S+            S GP     ++ 
Sbjct: 769  ---ECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLS 825

Query: 178  SSVFFNKLAFLPRSNLLLP-------QYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSS 230
            S V   + +FLP ++L            HS    S  GA T   +  ++P    LPP  +
Sbjct: 826  SPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKET 885

Query: 231  PSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEP 290
            P+ S + L   PFP +         AP Q+P  S     P  +    T   K +P +   
Sbjct: 886  PTPSVVNL---PFPKEG----PATPAPKQAPALSMTSSSP--KKARATPAPKGIPAS--- 933

Query: 291  PMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPP-LDSLPE 349
            P P    +P + + P   SP+GG A     W        P + +     P P    + P 
Sbjct: 934  PSPKGAPTPPAATPP---SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990

Query: 350  LQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQ 409
                S    P+   P+              +P     P ++  SP+  P A+  P KG  
Sbjct: 991  ATPPSPKGGPATPSPK-----------GAPTP-----PAVTPPSPKGSPAATPFP-KGAS 1033

Query: 410  SRENIWVPADPVSPPSLP-SVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPV 468
            +       A P SP   P + PL +     P   L   K    T   K       +P P 
Sbjct: 1034 TPP----AATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK------GAPTPP 1083

Query: 469  HSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVR 528
             +TPP+    P   +P        A    T  S     +  P       PA  P   +  
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAA----TPPSPKGGLATPPHKGAPTTPAATPPSPK-- 1137

Query: 529  SMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENC 588
                        G +       A   PA   P      SP G L+ +    G        
Sbjct: 1138 ------------GGLATPPPKGAPTTPAATPP------SPKGGLA-TPPPKGAPTTPAAT 1178

Query: 589  VPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSS----LS 644
             P   G  ++PS      +  + P + +      G A    K    T    P S    L+
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKG-----GLATPSPKGAPTTPAATPPSPKGGLA 1233

Query: 645  TPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGV 704
            TP P               +  P  P+     P      PP          T P L  G+
Sbjct: 1234 TPSP---------------KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278

Query: 705  TCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSS 764
              P  K  AP     T P     P                    SP   AP P  +   S
Sbjct: 1279 ATPPHKG-APNPAVVTPPSPKGGPA------------------TSPPKGAPTPPAATPPS 1319

Query: 765  PILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQL 824
            P  S   P   G P+  P  + PP+P          +   T+P    SS     +     
Sbjct: 1320 PKGSPGTPPPKGAPT--PPAVTPPSP----------KGTPTLPATTPSS-----KGGPTT 1362

Query: 825  QPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGP-GEPSNSKVLVSGK 883
               + G     +    K    M    P +GP +          P P G+P++  V+    
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI----------PSPKGDPTSPAVIPLSP 1412

Query: 884  RKDKASASSSAKKREHPRKPKAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQR 943
            +K    A ++   RE    P  GD       L    VT         SL +AP ++ P+ 
Sbjct: 1413 KK----APATPVTREGAATPSKGD-------LTPPAVT-------PVSLKKAPATSAPKG 1454

Query: 944  SQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYLSFPTL 1003
                  S     LP +  P       +P A ++ +   +P+     P       +  PTL
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPK----EPPAPKQVATSSSPKKAPATP-----APMGAPTL 1505

Query: 1004 KASLTRGLQKVLAKCLDNHRPL 1025
             A +    ++V A       P+
Sbjct: 1506 PAVIPSSPKEVPATPSSRRDPI 1527



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 113/503 (22%), Positives = 161/503 (32%), Gaps = 75/503 (14%)

Query: 219  APDPQLLPPPS------SPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGY 272
            AP      PPS      +PS           P   KG    A  P +   T P    P  
Sbjct: 1217 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG--GPATPPPKGAPTPPAATPPSL 1274

Query: 273  ETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQA 332
            +  L T  HK  P       P P   PA  + P K +P    A      G+ G    P+ 
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPA--TSPPKGAPTPPAATPPSPKGSPG-TPPPKG 1331

Query: 333  SESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGT 392
            + +   V  P     P L   +    PS            G      +P     P ++  
Sbjct: 1332 APTPPAVTPPSPKGTPTLPATT----PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387

Query: 393  SPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWET 452
            SP+   PA  +P KG  +   +     P+SP   P+ P+        +G  + SK     
Sbjct: 1388 SPK-RGPAIPSP-KGDPTSPAV----IPLSPKKAPATPVTR------EGAATPSKG---D 1432

Query: 453  MGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSL 512
            +        S    P  S P      P         A +  + K+    +  + S SP  
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKK 1492

Query: 513  A-LSPPPALAPELLRV---RSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASP 568
            A  +P P  AP L  V       V +   +R   I  T    + K PA   P++      
Sbjct: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552

Query: 569  LGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQ 628
            + V S  ++            P  P    +P++ S SK   S P    S YK      E 
Sbjct: 1553 MTVPSPKKT------------PAIPTPKEAPATPS-SKEASSPPAVTPSTYKGAPSPKEL 1599

Query: 629  RKNHWAT-----ELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQ 683
                  T     E P P +++ P PE               + P  P+P    P  P   
Sbjct: 1600 LIPPAVTSPSPKEAPTPPAVTPPSPE---------------KGPATPAPKGT-PTSPPVT 1643

Query: 684  PPTLAEAVKIERTHPGLPKGVTC 706
            P +L ++       P  P  VTC
Sbjct: 1644 PSSLKDS-------PTSPASVTC 1659


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 155/655 (23%), Positives = 199/655 (30%), Gaps = 130/655 (19%)

Query: 206 THGAHTMEDLEGMAPDPQLLPPPSSP--SVSSLLLH--LRPFPVDHKGVLSGAE------ 255
           +  A T   L   AP  +  PP   P  SVSS   H    P P   +   +G        
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239

Query: 256 ---APTQSPGTSPLEVLPGYETHLETTGHKKMP-----QAFEPPM--PP-----PCQSPA 300
              + + +P +SP    P          H   P     QA  PP   PP     P   P 
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299

Query: 301 SLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPS 360
           S S     SP G  A           R  P    ++ P+P   L   P L     L  PS
Sbjct: 300 SSSPLATPSPSGTKA-----------RPVPPPDNAATPLPAT-LPPSPPLATPLPLAPPS 347

Query: 361 RYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADP 420
              P                P L   P    T P   PP+  TP   MQ+          
Sbjct: 348 PSAP----------------PSLQTLPSPPATPPSQAPPSMTTP--PMQA---------- 379

Query: 421 VSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPH 480
             PPSL ++P ++     P  + S S            L A  SP  + S   TT +   
Sbjct: 380 --PPSLQTIPPIQV----PHSLTSPS------------LQAPPSPLALSSLQATTSLGSP 421

Query: 481 RINPGECLATSEATWKDTEHSRNSSAS-RSPSLALSPPPALAPELLRVRSMGVLSDSEAR 539
            +       T           R + AS  SPS   S PP  +P L    S+      +  
Sbjct: 422 TLQATHSFLTMSP--------RQTQASLTSPSRPASTPPD-SPPLQAPLSLPASPPLQTS 472

Query: 540 CGDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSP 599
                   +S  + HP   L   L   SP   LS    I+  +E + +  P        P
Sbjct: 473 LSPAVSPLSSPLTIHPLQAL-SSLASHSPQAPLSSL--IMPPLETQSSLAP--------P 521

Query: 600 SSNSVSKSHVSEPIADQSNYKP---DGEAVEQRKNHWATE-LPAPSSLSTPLPEPHIDLE 655
           S  +   S  + P+ +  +  P      +      H  T   PAP  L  P P P     
Sbjct: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP-PSPLTTPP 580

Query: 656 LVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHP--GLPKGVTCPGVKAEA 713
               +      PQ P  LA  PL  +P PP    A    +  P   LP     P   A  
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640

Query: 714 PLSQRWTV-PELLTHPGIHAWQW------------------SRELKLRLKKLRQSPASRA 754
           PLS   T  P+      +H  Q                   S  +        Q+P S A
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700

Query: 755 PGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQP 809
             P Q   S P      P     P  PP    PP   P S    P       P P
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 123/504 (24%), Positives = 164/504 (32%), Gaps = 107/504 (21%)

Query: 65  SLDPLKPCSPTKEAPTGEQATPAPPQPSCGS---EGLLKAIGIPEQTVMQPVSPSRSFPI 121
           +L PL        +P+G +A P PP  +  +     L  +  +     + P SPS   P 
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP-PS 353

Query: 122 FQILTSFPVRHKIASGNRQQQRKSQLFWGLP---------SLHSESLEAIFLSSGGPSPL 172
            Q L S P      +         Q    L          SL S SL+A       PSPL
Sbjct: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA------PPSPL 407

Query: 173 KWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPS 232
             S   +           ++L  P   ++  F T      +        P   PP S P 
Sbjct: 408 ALSSLQAT----------TSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL 457

Query: 233 VSSLLLHLRPFPVDHKGVLSGAEAPTQSPGT-SPLEVLPGYETH-------------LET 278
            + L L   P P+     LS A +P  SP T  PL+ L    +H             LET
Sbjct: 458 QAPLSLPASP-PLQTS--LSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514

Query: 279 TGHKKMPQAFEPP---MPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASES 335
                 P    PP     PP ++  SL+ P   +    L        T  + E P     
Sbjct: 515 QSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL--------TTPHLETPPC--- 563

Query: 336 SMPVPCP------PLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPEL 389
             P PCP      PL + P  +  SS+  P    P            A  SP L   P  
Sbjct: 564 --PAPCPLQAPPSPL-TTPPPETPSSIATPPPQAPP-----------ALASPPLQGLPS- 608

Query: 390 SGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKAL 449
              SP   PP    P   +   +       P SPP+ P  PL       PQ   + +  L
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQ------APPSPPASP--PLSPLATPSPQAPNALAVHL 660

Query: 450 WETMGQKENLWASDSPDP------VHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRN 503
                    L A  SP P        S P +  + P    P +   +  A       S  
Sbjct: 661 ---------LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711

Query: 504 SSASRSPSLA---LSPPPALAPEL 524
           +S   SPS      +PPP  AP L
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPL 735



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 143/668 (21%), Positives = 214/668 (32%), Gaps = 107/668 (16%)

Query: 227 PPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQ 286
           P ++PS S       P P D+      A  P   P  +PL + P        +    +  
Sbjct: 303 PLATPSPSGTKARPVP-PPDNAATPLPATLPPSPPLATPLPLAPP-----SPSAPPSLQT 356

Query: 287 AFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASES-SMPVPCPPLD 345
              PP  PP Q+P S++ P   +P            T+   + P +  S S+  P  PL 
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPS--------LQTIPPIQVPHSLTSPSLQAPPSPL- 407

Query: 346 SLPELQRESSLEDPSRYKPQ----WECRENSGNLWAFESPV--------------LDLNP 387
           +L  LQ  +SL  P+            R+   +L +   P               L  +P
Sbjct: 408 ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASP 467

Query: 388 EL-SGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSES 446
            L +  SP   P +S      +Q+  ++   +      SL   PL     + P  + +  
Sbjct: 468 PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP 527

Query: 447 KALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSA 506
            +L  T    ENL  S +P P+  T    L  PH   P      +    +       +  
Sbjct: 528 ASL--TTPPLENL-PSLAPPPLQ-TASAPLTTPHLETPP---CPAPCPLQAPPSPLTTPP 580

Query: 507 SRSPSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGA 566
             +PS   +PPP   P L      G+ S   +             +  P    P     +
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL-PPLQAPPSPPAS 639

Query: 567 SPLGVLSDSQSIVGEMEQKENCVPV--FPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGE 624
            PL  L+          Q  N + V       S P S  V           Q+ + P   
Sbjct: 640 PPLSPLATPSP------QAPNALAVHLLQAPFSPPPSPPV-----------QAPFSPPAS 682

Query: 625 AVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQP 684
                     ++ P PS  + PL  P         +      PQ P PLA  PL   P P
Sbjct: 683 PPVSPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 685 PTLAEAVKIERTHPGLPKGVTCPGVK------AEAPLS-----QRWTVPELLTHPGIHAW 733
           P            P +P  +  P ++      A  P+S          P L T P     
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPP----- 796

Query: 734 QWSRELKLRLKKLRQSPAS---RAP-GPSQSFCSSPILSS-------TIPDFWGLPSCPP 782
                    L+ L   PAS   +AP  PS S   SP+ +               +P  PP
Sbjct: 797 ---------LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 847

Query: 783 QQ------IYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGS 836
                     PP P P +S   P+      P P          SS+   P  +G +   +
Sbjct: 848 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP--SRSPSSTLSGPDLAGHSSSAT 905

Query: 837 QRGEKMKG 844
              E+++G
Sbjct: 906 STPEELRG 913



 Score = 38.1 bits (87), Expect = 0.043
 Identities = 79/317 (24%), Positives = 100/317 (31%), Gaps = 81/317 (25%)

Query: 215 LEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYET 274
           L+G+ P P L P  + P  +   L L P        L    +P  SP  SPL   P  + 
Sbjct: 603 LQGL-PSPPLSPLATPPPQAPPXLALPP--------LQAPPSPPASPPLSPLAT-PSPQA 652

Query: 275 HLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASE 334
                 H  +   F PP  PP Q+P S      VSP                      S+
Sbjct: 653 PNALAVHL-LQAPFSPPPSPPVQAPFSPPASPPVSPSA-----------------TPPSQ 694

Query: 335 SSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSP 394
           +   +  PPL   P       +   +   PQ      +  L    SP        S T P
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754

Query: 395 ECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWETMG 454
             VPP    P         + VP  P  P SLP  PL +     P               
Sbjct: 755 PRVPPLLAAP--------PLQVPPSP--PASLPMSPLAKPPPQAP--------------- 789

Query: 455 QKENLWASDSPDPVHSTPP-TTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLA 513
                       P  +TPP   L  P    PG+              S ++S   SP LA
Sbjct: 790 ------------PALATPPLQALPSPPASFPGQ-----------APFSPSASLPMSP-LA 825

Query: 514 LSP---PPALAPELLRV 527
             P   PP LA  LL+V
Sbjct: 826 TPPPQAPPVLAAPLLQV 842



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 110/468 (23%), Positives = 150/468 (32%), Gaps = 92/468 (19%)

Query: 65   SLDPLK-PCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQT--VMQPVSPSRSFPI 121
            +L PL+ P SP    P    ATP+P  P+  +  LL+A   P  +  V  P SP  S P+
Sbjct: 626  ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685

Query: 122  FQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVF 181
                T                  SQ     PSL +  L+        PSP          
Sbjct: 686  SPSATP----------------PSQ---APPSLAAPPLQV------PPSPP--------- 711

Query: 182  FNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAP-DPQLLPPPSSPSV-SSLLLH 239
                A  P S    P   +    +              P  P   PPP  P + ++  L 
Sbjct: 712  ----ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767

Query: 240  LRPFPVDHKGVLSGAEAPTQSP---GTSPLEVLP-------GYETHLETTGHKKMPQAFE 289
            + P P     +   A+ P Q+P    T PL+ LP       G      +      P A  
Sbjct: 768  VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827

Query: 290  PPMPPPCQSPASLSEPRK--VSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSL 347
            PP  PP  +   L  P     SP           G       P+ + +  P P PP    
Sbjct: 828  PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP---- 883

Query: 348  PELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKG 407
            P     S+L  P               L  ++S      PE  G +    PP +E     
Sbjct: 884  PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS-----GPE--GGAAASPPPDAEL---- 932

Query: 408  MQSRENIWV--PADPVSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSP 465
                   W   PA P++    P  PL      GP G       ++ET G           
Sbjct: 933  AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGP-GSADGLCTIYETEG----------- 980

Query: 466  DPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLA 513
             P  +TP      P  ++PG    TS    K    +   ++SRSP  A
Sbjct: 981  -PESATP-----APGALDPGPSPGTSGG--KAAAGAGAGASSRSPKQA 1020


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 115/475 (24%), Positives = 165/475 (34%), Gaps = 79/475 (16%)

Query: 64  ASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSR--SFPI 121
           +S  PL   SP +  P+      AP  PS      L+A+  P+      V+P R  + P 
Sbjct: 244 SSATPLS--SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ------VTPPRKDAAPA 295

Query: 122 FQILTSFPVRHKIASGNRQQQRKSQLFWGLPSL-HSESLEAIFLSSGGPSPLKWSVCSSV 180
              L+S P+     S   Q Q    L    P+  HS SL     +     PL  +  S  
Sbjct: 296 LGPLSSSPLATPSPSAALQSQAPPTL----PATPHSSSLTCQLAT-----PLPLAPPSPS 346

Query: 181 FFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHL 240
               L  LP      P    S   ++ G+ T++      P P L P  + P  +   L L
Sbjct: 347 APPSLQTLPSP----PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402

Query: 241 RPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPA 300
            P        L    +P  SP  SPL   P  +       H  +   F PP  PP Q+P 
Sbjct: 403 PP--------LQAPPSPPASPPLSPLAT-PSPQAPNALAVHL-LQAPFSPPPSPPVQAPF 452

Query: 301 SLSEPRKVSPEG--------GLAISKDFWGTVGYREKPQASESSMPVP--CPPLDSLP-E 349
           S      VSP           LA +            P  S S+ P P   PPL + P +
Sbjct: 453 SPPASPPVSPSATPPSQAPPSLA-APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 511

Query: 350 LQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELS-GTSPECVPPASETPWKGM 408
           L +      P+   P  +   +    +  ++P    +P  S   SP   PP    P   +
Sbjct: 512 LAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPSASLPMSPLATPPPQAPP---V 565

Query: 409 QSRENIWVPADPVSPPSL-----PSVPLLESLVMGPQGVLSESKALWETMGQKENLWASD 463
            +   + VP  P + P+L     P  P  ++ V GP+  L+                A  
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA---------------LAPG 610

Query: 464 SPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPP 518
            P P   +P +TL  P      +    S +     E  R   +      A SPPP
Sbjct: 611 PPPPPSRSPSSTLSGP------DLAGHSSSATSTPEELRGYDSGPEGGAAASPPP 659



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 167/733 (22%), Positives = 241/733 (32%), Gaps = 142/733 (19%)

Query: 227 PPSSPSVSSLLLHLRPFPVDHKGVLSGAEAP------TQSPGTSPLEVLPGYETHLETTG 280
           P SSP  +S     RP P+  KG+   AE        T++P  S L           + G
Sbjct: 113 PVSSPGRASGTT--RPGPLGQKGLRISAEETVARGKATEAPKRSAL-----------SAG 159

Query: 281 HKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREK-PQASESSMPV 339
            ++      P  P P  +  S +   +V        ++    T G R+    ASE S   
Sbjct: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219

Query: 340 PCPPLDSLPE----LQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPE 395
           P P     P     LQR +S             R  S +     SP     P   GT   
Sbjct: 220 PSPAARRRPSAGGGLQRPAS-------------RSLSSSATPLSSPARS-GPSARGTPRA 265

Query: 396 CVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQ 455
              P+   P KG+Q+     +    V+PP   + P L  L   P    S S AL      
Sbjct: 266 PAHPSQPKP-KGLQA-----LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS---- 315

Query: 456 KENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLALS 515
                           PPT    PH  +    LAT              S S  PSL   
Sbjct: 316 --------------QAPPTLPATPHSSSLTCQLATPLPL-------APPSPSAPPSLQTL 354

Query: 516 PPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDS 575
           P P   P      S+G  +        +Q T +S+    P   L      A P   L   
Sbjct: 355 PSPPATPPSQATTSLGSPT--------LQAT-HSFLPSPPLSPLATPPPQAPPALALPPL 405

Query: 576 QSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHV---------SEPIADQSNYKPDGEAV 626
           Q+            P+ P    SP + +    H+         S P+  Q+ + P     
Sbjct: 406 QAPPSPPASP----PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV--QAPFSPPASPP 459

Query: 627 EQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLH---PVPQ 683
                   ++ P PS  + PL  P         +      PQ P PLA  PL    P PQ
Sbjct: 460 VSPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518

Query: 684 -PPTLA-EAVKIERTHPGLPKGVTCPGVKAEAPLSQRWT----VPELLTHPGIHAWQWSR 737
            PP LA   ++   + P    G       A  P+S   T     P +L  P +     S 
Sbjct: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV-PPSP 577

Query: 738 ELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPS-CPPQQIYPPNPCPHSSS 796
                L+  R+ P    PGP  S     +  +  P     PS  P   +  P+   HSSS
Sbjct: 578 PASPTLQAPRRPP---TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634

Query: 797 C--HPQEVQ-----------RTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMK 843
               P+E++            + P   + + CH    S    P  + R   G+       
Sbjct: 635 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP------ 688

Query: 844 GKMVSQVPSQGP-------CVHMEAGVDYLSPGPG--EPSNSKVLVSGKRKDKASASSSA 894
              +   P+ GP        ++   G +  +P PG  +P  S     GK    A A +S+
Sbjct: 689 ---LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 745

Query: 895 KKREHPRKPKAGD 907
           +    P++ + G+
Sbjct: 746 RS---PKQARLGE 755


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 106/421 (25%), Positives = 161/421 (38%), Gaps = 93/421 (22%)

Query: 217  GMAPDPQ---LLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYE 273
            G  P P+   L PPP  PS+S LL                 E     PG  PL  LP  E
Sbjct: 872  GQCPAPEELPLFPPPGEPSLSPLL----------------GEPALSEPGEPPLSPLP-EE 914

Query: 274  THLETTGHKKM-PQAFEP-PMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQ 331
              L  +G   + PQ   P P+PPP     + + P  +SP G L      +G  G      
Sbjct: 915  LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYP---FGAKG------ 965

Query: 332  ASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSG 391
             S+   P+  P L++      E++  DP    P      + G+     SP+L     +  
Sbjct: 966  DSDPESPLAAPILETPISPPPEANCTDPEPVPPM-ILPPSPGSPVGPASPIL-----MEP 1019

Query: 392  TSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWE 451
              P+C P             ++  VP +  SPPS  S P L      P  V S    + +
Sbjct: 1020 LPPQCSP-----------LLQHSLVPQN--SPPSQCSPPAL------PLSVPSPLSPIGK 1060

Query: 452  TMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPS 511
             +G       SD  + +H       ME  +++  EC A   +          +S   SP 
Sbjct: 1061 VVG------VSDEAE-LHE------METEKVSEPECPALEPSA---------TSPLPSPM 1098

Query: 512  LALS-PPPALAPELLRVRSMGVLS------DSEARCGDIQKTKNSWASK---HPACNLPQ 561
              LS P P+ AP L     +G  +      D+     +  +T  S AS+    P    P+
Sbjct: 1099 GDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPE 1158

Query: 562  DLHGASPLGVLSDSQSIVGE----MEQKENCVPVFPGRGSSPSSNSVSK-SHVSEPIADQ 616
            +L   +P+ V  + +   G+     EQ+E   PV P   +   S+ V++ S++S+  A  
Sbjct: 1159 ELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASA 1218

Query: 617  S 617
            S
Sbjct: 1219 S 1219



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 136/572 (23%), Positives = 184/572 (32%), Gaps = 121/572 (21%)

Query: 262 GTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPAS-------LSEPRKVSPEGGL 314
           G + +++ P  E  L        P    P  PPP +SP S       LS P +  P   L
Sbjct: 420 GKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL 479

Query: 315 AISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGN 374
                          P+A   S P+   PL   PE   ES L  P    P          
Sbjct: 480 ---------------PEALHLSRPLEESPLSPPPE---ESPLSPPPESSPFSPLE----- 516

Query: 375 LWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPP--SLPSVPLL 432
               ESP+    PE S  SP    P S  P             A P+SPP    P  P  
Sbjct: 517 ----ESPLSP--PEESPPSPALETPLSPPP------------EASPLSPPFEESPLSPPP 558

Query: 433 ESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSE 492
           E L   P    S            E    S  P+    +PP    E  R+ P    +   
Sbjct: 559 EELPTSPPPEASRLSP------PPEESPMSPPPEESPMSPPP---EASRLFPPFEESPLS 609

Query: 493 ATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWAS 552
              +++  S    ASR     LSPPP  +P                          S   
Sbjct: 610 PPPEESPLSPPPEASR-----LSPPPEDSP-------------------------MSPPP 639

Query: 553 KHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEP 612
           +    + P ++   SPL V+S        +       P+ P    SP+S     S +S P
Sbjct: 640 EESPMSPPPEVSRLSPLPVVS-------RLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692

Query: 613 IADQ-SNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGP- 670
             D  ++  P+              LP   S   PLPE   + +L  R+       +GP 
Sbjct: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE---EPQLCPRS-------EGPH 742

Query: 671 -SPLAVDP-LHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHP 728
            SP   +P L P P+ P L+   +     P   +   C  V  E  LS +   P L   P
Sbjct: 743 LSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC-AVPEEPHLSPQAEGPHLSPQP 801

Query: 729 -GIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCS----SPILSSTIPDFWGLPSC--P 781
             +H    + E    L  + + P   +P P +S  S     P LS    +    P    P
Sbjct: 802 EELHLSPQTEE--PHLSPVPEEPC-LSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP 858

Query: 782 PQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSS 813
           P    P  P      C   E     P P + S
Sbjct: 859 PLSPRPEKPPEEPGQCPAPEELPLFPPPGEPS 890



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 66/246 (26%), Positives = 93/246 (37%), Gaps = 36/246 (14%)

Query: 589 VPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLP 648
           +P+ P    SP S    +S  S P  + S   P  E +       A+ LP    LS PL 
Sbjct: 438 MPLLPPPEESPLSPPPEESPTSPP-PEASRLSPPPEELP------ASPLPEALHLSRPLE 490

Query: 649 EPHIDLELVWRNVQQREVPQGP-------SPLAVDPLHPVPQPPTLAEAVKIERTHPGLP 701
           E  +       +    E P  P       SPL   PL P  + P  + A++   + P  P
Sbjct: 491 ESPL-------SPPPEESPLSPPPESSPFSPLEESPLSPPEESPP-SPALETPLSPP--P 540

Query: 702 KGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSF 761
           +         E+PLS      EL T P   A + S   +       +SP S  P P +S 
Sbjct: 541 EASPLSPPFEESPLSP--PPEELPTSPPPEASRLSPPPE-------ESPMS--PPPEESP 589

Query: 762 CSSPILSSTI-PDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQS 820
            S P  +S + P F   P  PP +  P +P P +S   P      +  P + S       
Sbjct: 590 MSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPE 649

Query: 821 SSQLQP 826
            S+L P
Sbjct: 650 VSRLSP 655



 Score = 38.1 bits (87), Expect = 0.043
 Identities = 81/335 (24%), Positives = 122/335 (36%), Gaps = 48/335 (14%)

Query: 555 PACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIA 614
           PA  LP+ LH + PL      +S +    ++    P+ P   SSP S  + +S +S P  
Sbjct: 475 PASPLPEALHLSRPL-----EESPLSPPPEES---PLSPPPESSPFS-PLEESPLSPP-- 523

Query: 615 DQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLA 674
                 P   A+E       T L  P   S PL  P  +  L   +    E+P  P P A
Sbjct: 524 ---EESPPSPALE-------TPLSPPPEAS-PLSPPFEESPL---SPPPEELPTSPPPEA 569

Query: 675 V--------DPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLT 726
                     P+ P P+   ++   +  R  P   +    P  + E+PLS       L  
Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPE-ESPLSPPPEASRLSP 628

Query: 727 HPGIHAWQWSRE---LKLRLKKLRQSP----ASRAPGPSQSFCSSPILSS-TIPDFWGLP 778
            P         E   +    +  R SP    +  +P P +S  S P   S T P      
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688

Query: 779 SCPPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQR 838
             PP +  P +P P  S   P      +  P++ S         QL P+      +G   
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPR-----SEGPHL 743

Query: 839 GEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEP 873
             + +   +S  P + P +  +A   +LSP P EP
Sbjct: 744 SPRPEEPHLSPRPEE-PHLSPQAEEPHLSPQPEEP 777



 Score = 37.4 bits (85), Expect = 0.073
 Identities = 56/238 (23%), Positives = 88/238 (36%), Gaps = 49/238 (20%)

Query: 569  LGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPI----ADQSNYKP--D 622
            +G+L+ S++++   +Q++  V + PG  + P  +  S   +   +     +Q+   P   
Sbjct: 3975 MGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVS 4034

Query: 623  GEAVEQRKNHWATEL---PAPSSLSTPLPE--PHIDLELVWRNVQQREVPQGPSPLAVDP 677
             EA E    H    L     P S++T   E  P +  +     VQ +  PQ PS L + P
Sbjct: 4035 SEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ-PSSLQLQP 4093

Query: 678  LHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSR 737
              P+  P    + V +  T  G   G    G  +EA      +VP LL  P +       
Sbjct: 4094 --PLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEAS-----SVPHLLAQPSV------- 4139

Query: 738  ELKLRLKKLRQSPASRAP---GPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCP 792
                    L   P S      GP Q     P+ ++T P              PP P P
Sbjct: 4140 -------SLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ-------------PPKPGP 4177



 Score = 37.0 bits (84), Expect = 0.096
 Identities = 134/592 (22%), Positives = 194/592 (32%), Gaps = 118/592 (19%)

Query: 224 LLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKK 283
           LLPPP    +S         P      LS    P +    SPL         LE +    
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLS---PPPEELPASPLPEALHLSRPLEESPLSP 496

Query: 284 MPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPP 343
            P+   P  PPP  SP S  E   +SP      S            P+AS  S P    P
Sbjct: 497 PPEE-SPLSPPPESSPFSPLEESPLSPPEESPPSPAL--ETPLSPPPEASPLSPPFEESP 553

Query: 344 LDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASET 403
           L   PE    S   + SR  P  E           ESP+               PP  E+
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPE-----------ESPM--------------SPPPEES 588

Query: 404 PWKGMQSRENIWVPAD--PVSPP--SLPSVPLLESLVMGPQGVLSESKALWETMGQKENL 459
           P         ++ P +  P+SPP    P  P  E+  + P                    
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP------------------- 629

Query: 460 WASDSP--DPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHS---RNSSASRSPSLA- 513
              DSP   P   +P +   E  R++P   ++      +++  S     S  S  P  + 
Sbjct: 630 -PEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688

Query: 514 LSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGASPLGVLS 573
           LSPPP  +P                         +      PA   P+D   + PL    
Sbjct: 689 LSPPPEDSP------------------------TSPPPEDSPASPPPEDSLMSLPL---- 720

Query: 574 DSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHW 633
             +S +  + ++    P   G   SP      + H+S P  ++ +  P  E     + H 
Sbjct: 721 -EESPLLPLPEEPQLCPRSEGPHLSPRP---EEPHLS-PRPEEPHLSPQAE-----EPHL 770

Query: 634 ATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDP-LHPVPQPPTLAEAVK 692
           + +   P   + P  EPH+  +    ++  +      SP   +P L PVP+ P L+   +
Sbjct: 771 SPQPEEPCLCAVP-EEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPE 829

Query: 693 IERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSR-----ELKL------ 741
                P   +    P  + E+ LS     P L   P     +  +     EL L      
Sbjct: 830 ESHLSPQSEEPCLSPRPE-ESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGE 888

Query: 742 -RLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCP 792
             L  L   PA   PG       SP+         G PS  P Q+ PP+P P
Sbjct: 889 PSLSPLLGEPALSEPGEPP---LSPLPEELPLSPSGEPSLSP-QLMPPDPLP 936



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 56/228 (24%), Positives = 79/228 (34%), Gaps = 22/228 (9%)

Query: 599 PSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVW 658
           P    V+     EP   Q   KP G+A  Q +     +L AP +   PL  P        
Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLE----PQLEAPLNEEMPLLPP-------- 443

Query: 659 RNVQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQR 718
                 E P  P P    P  P P+   L+   +     P LP+ +       E+PLS  
Sbjct: 444 ----PEESPLSPPP-EESPTSPPPEASRLSPPPEELPASP-LPEALHLSRPLEESPLSP- 496

Query: 719 WTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLP 778
               E    P   +  +S   +  L    +SP S  P         P  S   P F   P
Sbjct: 497 -PPEESPLSPPPESSPFSPLEESPLSPPEESPPS--PALETPLSPPPEASPLSPPFEESP 553

Query: 779 SCPPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQP 826
             PP +  P +P P +S   P   +  +  P + S       +S+L P
Sbjct: 554 LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFP 601



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 56/222 (25%), Positives = 87/222 (39%), Gaps = 20/222 (9%)

Query: 599  PSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPA--PSSLS---TPLPEPHID 653
            P S  V     SEP+     +    +A+E +K       P+  P +L    +P    H+ 
Sbjct: 2258 PESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLG 2317

Query: 654  -LELVWRNVQQREVPQGPSPLAVDPLHPV----PQPPTLAEAVKIER-THPGLPKGVTCP 707
             LEL   +V +   P  P    V+P  P     PQ P  A+A+     +HP + +  +  
Sbjct: 2318 GLELKTPDVFK--APLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYT 2375

Query: 708  GVKAEAPLSQRWTVPE-----LLTHPGIHAWQWSR-ELKLRLKKLRQSPASRAPGPSQSF 761
               A+ PL+ R   P       L    + +  +SR     + +   QSP +  P  +++F
Sbjct: 2376 DPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAF 2435

Query: 762  CSSPILSS-TIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEV 802
            C SP+      PD +  P   PQ   P  P        P EV
Sbjct: 2436 CPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEV 2477



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 82/406 (20%), Positives = 138/406 (33%), Gaps = 87/406 (21%)

Query: 663  QREVPQGPSPLAVDPLHPVPQ---PPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQR- 718
            Q++  QGP       L P PQ   PP+  + + +++  P  P+G       A+  + Q+ 
Sbjct: 3754 QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQ 3813

Query: 719  ---------------WTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCS 763
                            T   +L+ P + A Q    +  RL   +Q    +      S   
Sbjct: 3814 HPGALGPQGPHRQVLMTQSRVLSSPQL-AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAG 3872

Query: 764  SPILSSTIPDFWGLP--SCPP----QQIYPPNPCPHSSSCHPQEVQRTVPQP-VQSSHCH 816
               L  ++    G P  S  P    QQ+              Q+ Q+   Q  +Q     
Sbjct: 3873 LSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQ 3932

Query: 817  HFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHM---EAGVDYLSP----- 868
              Q   QLQ Q+  + +Q  Q+ ++ + +   Q   Q     M         LSP     
Sbjct: 3933 QQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQ 3992

Query: 869  -----GPGEPSNS------------KVLVSGKRKDKASASSSAKKREHPRKPKAGDHRRG 911
                 GPG P+               +L++GK ++    + S++  E P   + G    G
Sbjct: 3993 QQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIG 4052

Query: 912  TARLGLSTVTGKNHPA----------------QARSLVEAPVSTFPQRSQHR-------- 947
            T    ++T  G+  P+                Q  SL   P    P + Q +        
Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112

Query: 948  ---------GQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPR 984
                     G SS+ +++P LL   +    DQP  G    ++L P+
Sbjct: 4113 GGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQP--GSMTQNLLGPQ 4156



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 73/327 (22%), Positives = 121/327 (37%), Gaps = 57/327 (17%)

Query: 215  LEGMAPDP---QLLPPP----SSPSVSSLLLHLRPFPVDHKG---------VLSGAEAPT 258
            L G+ P P   +  PPP    S P ++S+L  ++P  V+  G         + +    P 
Sbjct: 3086 LRGVEPGPLGPEERPPPAADASEPRLASVLPEVKP-KVEEGGRHPSPCQFTIATPKVEPA 3144

Query: 259  QSPGTSPLEVLPGY------ETHLET-----TGHKKMPQAFEPPMPPPCQSPASLSEPRK 307
             +  +  L + PG       +T + T     +GH     +F     PP    A L  P  
Sbjct: 3145 PAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPP----AHLLTPSP 3200

Query: 308  VSPEGGLAISKDFW---GTVGYREKPQAS-------ESSMPVPCPPL-------DSLPEL 350
            +S  GG ++ + F    G +     P AS       ESS+     PL           EL
Sbjct: 3201 LSGPGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKEL 3260

Query: 351  QRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQS 410
            Q++  L    +   Q + ++   +L +   P   ++    G+SP       +    G+  
Sbjct: 3261 QKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSL-GLAG 3319

Query: 411  RENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHS 470
                 +P  P+ P   P+  L + L      V ++   L    G +  L    S  PV S
Sbjct: 3320 ARQPGLP-QPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLS 3378

Query: 471  ------TPPTTLMEPHRINPGECLATS 491
                   PP+  M+P ++   + LA S
Sbjct: 3379 QKPMGTMPPSMCMKPQQLAMQQQLANS 3405


>gi|155029550 chromosome 9 open reading frame 79 [Homo sapiens]
          Length = 1445

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 39/149 (26%), Positives = 63/149 (42%), Gaps = 16/149 (10%)

Query: 840  EKMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREH 899
            + + GK  +   SQGPC  +  G D  SPG  EP + K     K +     +   +    
Sbjct: 1154 QSVSGK--NMTASQGPCALLWKGGD--SPGQQEPGSPKAKAPQKSQKTLGCADKGEAHRR 1209

Query: 900  PRKPKAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVSTFPQRSQHRGQSSQHTAL--- 956
            PR  + G   +G      S  +G++HPAQAR + +     + Q    +GQ+   +     
Sbjct: 1210 PRTGEQGHRSKGPRT---SEASGRSHPAQAREIGDKQERKYNQLQLEKGQTPPESHFQRK 1266

Query: 957  ----PQLLLPKASGP--QDQPEAGRRASD 979
                PQ L P+  G   +D  + G+  +D
Sbjct: 1267 ISHHPQGLHPRKGGTRWEDVLQKGKPGAD 1295



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 60/190 (31%), Positives = 77/190 (40%), Gaps = 33/190 (17%)

Query: 137 GNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVFFNKLA-FLPRSNLLL 195
           GN  QQ++SQLFW LPSL+SESL      S  PS        SV  +K +  LP      
Sbjct: 429 GNHLQQKRSQLFWDLPSLNSESLATTVWVSRNPSSQN---AHSVPLDKASTSLPGE---- 481

Query: 196 PQYHSSAQFS--THGAHTMEDLEGMAPD-PQLLPPPSSPSVSSLLLHLRPFPVDHKGVLS 252
           P+  +S+Q S      H M   +   P  PQ  PPP +   +    HL P PV   G  S
Sbjct: 482 PEVEASSQLSQAPPQPHHMAQPQHFTPAWPQSQPPPLAEIQTQ--AHLSP-PVPSLGCSS 538

Query: 253 -------GAEAPTQSPGTS------------PLEVLPGYETHLETTGHKKMPQAFEPPMP 293
                  GA  PT    T             PL+  P ++  L +   K      +P   
Sbjct: 539 PPQIRGCGASYPTSQERTQSVIPTGKEYLEWPLKKRPKWKRVLPSLLKKSQAVLSQPTAH 598

Query: 294 PPCQSPASLS 303
            P + PAS S
Sbjct: 599 LPQERPASWS 608



 Score = 35.0 bits (79), Expect = 0.36
 Identities = 68/274 (24%), Positives = 87/274 (31%), Gaps = 63/274 (22%)

Query: 636 ELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIER 695
           E+ A S LS   P+PH                    P    P  P  QPP LAE      
Sbjct: 483 EVEASSQLSQAPPQPH----------------HMAQPQHFTPAWPQSQPPPLAEIQTQAH 526

Query: 696 THPGLPK-GVTCP----GVKAEAPLSQRWTVPELLTHPGIHAW------QWSRELKLRLK 744
             P +P  G + P    G  A  P SQ  T   + T      W      +W R L   LK
Sbjct: 527 LSPPVPSLGCSSPPQIRGCGASYPTSQERTQSVIPTGKEYLEWPLKKRPKWKRVLPSLLK 586

Query: 745 K---LRQSPASRAP---GPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCH 798
           K   +   P +  P     S S  S+PIL   +      P  P       N      SC 
Sbjct: 587 KSQAVLSQPTAHLPQERPASWSPKSAPILPGVVTS----PELPEHWWQGRNAIHQEQSCG 642

Query: 799 PQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVH 858
           P       P  +Q+       S   LQP         SQ  +  +  + SQ PS      
Sbjct: 643 P-------PSRLQA-------SGDLLQPDGEFPGRPQSQAEDTQQALLPSQ-PS------ 681

Query: 859 MEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASS 892
                D+   G  +   +    SG+  DK    S
Sbjct: 682 -----DFAGKGRKDVQKTGFRSSGRFSDKGCLGS 710


>gi|148612857 sickle tail isoform 3 [Homo sapiens]
          Length = 1309

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 64/249 (25%), Positives = 100/249 (40%), Gaps = 26/249 (10%)

Query: 188  LPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDH 247
            LPR +  + +   S   S +    +E L G +P P   PP  S    S L   R   V +
Sbjct: 979  LPRGDAPVDKVELSED-SPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVY 1037

Query: 248  KGVLSG--AEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEP 305
             G      A+A ++  G SP      Y          + P +   P PPP  + +S  E 
Sbjct: 1038 TGRKENITAKASSEDAGPSPQTRATKYPA--------EEPASAWTPSPPPVTTSSSKDEE 1089

Query: 306  RKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLD---SLPELQRESSLEDPSRY 362
             +   E G  I  +  G+ G    PQ S   MPVP    +   +L +  ++S L+DP +Y
Sbjct: 1090 EE--EEEGDKIMAELQGSSG---APQTSR--MPVPMSAKNRPGTLDKPGKQSKLQDPRQY 1142

Query: 363  KPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVS 422
            +      + SG  +   SP L      +   P   P + ++      S ++  +P  P +
Sbjct: 1143 RQANGSAKKSGGDFKPTSPSLP-----ASKIPALSPSSGKSSSLPSSSGDSSNLPNPPAT 1197

Query: 423  PPSLPSVPL 431
             PS+ S PL
Sbjct: 1198 KPSIASNPL 1206


>gi|148612813 sickle tail isoform 2 [Homo sapiens]
          Length = 1264

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 64/249 (25%), Positives = 100/249 (40%), Gaps = 26/249 (10%)

Query: 188  LPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDH 247
            LPR +  + +   S   S +    +E L G +P P   PP  S    S L   R   V +
Sbjct: 934  LPRGDAPVDKVELSED-SPNSEQDLEKLGGKSPPPPPPPPRRSYLPGSGLTTTRSGDVVY 992

Query: 248  KGVLSG--AEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEP 305
             G      A+A ++  G SP      Y          + P +   P PPP  + +S  E 
Sbjct: 993  TGRKENITAKASSEDAGPSPQTRATKYPA--------EEPASAWTPSPPPVTTSSSKDEE 1044

Query: 306  RKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLD---SLPELQRESSLEDPSRY 362
             +   E G  I  +  G+ G    PQ S   MPVP    +   +L +  ++S L+DP +Y
Sbjct: 1045 EE--EEEGDKIMAELQGSSG---APQTSR--MPVPMSAKNRPGTLDKPGKQSKLQDPRQY 1097

Query: 363  KPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVS 422
            +      + SG  +   SP L      +   P   P + ++      S ++  +P  P +
Sbjct: 1098 RQANGSAKKSGGDFKPTSPSLP-----ASKIPALSPSSGKSSSLPSSSGDSSNLPNPPAT 1152

Query: 423  PPSLPSVPL 431
             PS+ S PL
Sbjct: 1153 KPSIASNPL 1161


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 81/284 (28%), Positives = 103/284 (36%), Gaps = 45/284 (15%)

Query: 269 LPGYETHLETTGHKKMPQAFEP----PMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTV 324
           +P      +  G    P++ +P    P+ P  Q P S+  P   +P      SK    +V
Sbjct: 127 IPALSMETQKLGSVLSPESPKPTPLTPLEP--QKPGSVVSPELQTPLPSPEPSKP--ASV 182

Query: 325 GYREKPQA-----SESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECR--ENSGNLWA 377
              E P++     S+   PVP P       +  ES     S  KPQ +    E  G   A
Sbjct: 183 SSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSA 242

Query: 378 F--ESPVLDLNPELSGTSPECVPPA-------SETPWKGMQSRE-NIWVPADPVSPPSLP 427
              ESPVL  +PE  G SP   P +       S  P K   S     W P   VSP    
Sbjct: 243 SSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRR 302

Query: 428 SVPLLE--SLVMGPQGVLSESKALWETMGQKENLWASDSP----DPVHSTPPTTLMEPHR 481
             P +   S   GP G    S   W     K N  AS  P     P  S  P        
Sbjct: 303 PAPAVSPGSWKPGPPG----SPRPW-----KSNPSASSGPWKPAKPAPSVSPGPWKPIPS 353

Query: 482 INPGECLAT---SEATWKDTEHSRNS--SASRSPSLALSPPPAL 520
           ++PG    T   S A+WK +  S +S  S   SP    S PP L
Sbjct: 354 VSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPEL 397



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 76/314 (24%), Positives = 95/314 (30%), Gaps = 119/314 (37%)

Query: 222 PQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGH 281
           P+ L PPS+ S  S +L   P                                       
Sbjct: 234 PETLGPPSASSPESPVLAASP--------------------------------------- 254

Query: 282 KKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPC 341
                  EP  P P  SP S    R  SPE                 KP  SES  P P 
Sbjct: 255 -------EPWGPSPAASPESRKSARTTSPE---------------PRKPSPSES--PEPW 290

Query: 342 PPLDSL-PELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPA 400
            P  ++ PE +R +    P  +KP                                 PP 
Sbjct: 291 KPFPAVSPEPRRPAPAVSPGSWKPG--------------------------------PPG 318

Query: 401 SETPWKGMQSREN-IWVPADP---VSPPSLPSVPLLESLVMGP-QGVLSESKALWETMGQ 455
           S  PWK   S  +  W PA P   VSP     +P   S+  GP +   S S A W++   
Sbjct: 319 SPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIP---SVSPGPWKPTPSVSSASWKSSSV 375

Query: 456 KENLWASD--SPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLA 513
             + W S   SP+   S PP        ++P    A              S   R P   
Sbjct: 376 SPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPV----------SPELRKPGPP 425

Query: 514 LSP---PPALAPEL 524
           LSP    PA +PEL
Sbjct: 426 LSPEIRSPAGSPEL 439



 Score = 31.6 bits (70), Expect = 4.0
 Identities = 64/268 (23%), Positives = 93/268 (34%), Gaps = 48/268 (17%)

Query: 256 APTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLA 315
           APT SP     + +P     L   G         PP+ P  +SPA   E RK  P G   
Sbjct: 401 APTLSP--EHWKAVPPVSPELRKPG---------PPLSPEIRSPAGSPELRK--PSG--- 444

Query: 316 ISKDFWGTVGYREKPQASESSMPVPCPPLDS---LPELQRESSLEDPSRYKPQWECRENS 372
            S D W     + K   S +S+  P     S    P+L + S   +P   KP +      
Sbjct: 445 -SPDLWKLSPDQRK--TSPASLDFPESQKSSRGGSPDLWKSSFFIEPQ--KPVFPETRKP 499

Query: 373 GNLWAFESP-----------VLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPV 421
           G     ESP            +D  P      PE   PA   P    ++R+    P +P 
Sbjct: 500 GPSGPSESPKAASDIWKPVLSIDTEPRKPALFPE---PAKTAPPASPEARKRALFP-EPR 555

Query: 422 SPPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHR 481
                P +P           + SES+   E +G +  + A D            L  P +
Sbjct: 556 KHALFPELP--------KSALFSESQKAVE-LGDELQIDAIDDQKCDILVQEELLASPKK 606

Query: 482 INPGECLATSEATWKDTEHSRNSSASRS 509
           +       +S+   KD + S ++  S S
Sbjct: 607 LLEDTLFPSSKKLKKDNQESSDAELSSS 634



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 93/432 (21%), Positives = 137/432 (31%), Gaps = 75/432 (17%)

Query: 590  PVFPGRGSSPSSNSV--SKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPS-----S 642
            PV P    +  SN     +SH  E +   S   P+   +      W    PA S     S
Sbjct: 212  PVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPS-PAASPESRKS 270

Query: 643  LSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPV-PQPPTLAEAVKIERTHPGLP 701
              T  PEP             R+     SP    P   V P+P   A AV      PG P
Sbjct: 271  ARTTSPEP-------------RKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPG-P 316

Query: 702  KGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSF 761
             G   P     +  S  W   +    P +    W     +       SP    P PS S 
Sbjct: 317  PGSPRPWKSNPSASSGPWKPAK--PAPSVSPGPWKPIPSV-------SPGPWKPTPSVSS 367

Query: 762  CSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHCHHFQSS 821
             S           W   S  P     P   P S    P E+++T P    +    H+++ 
Sbjct: 368  AS-----------WKSSSVSPSSWKSPPASPESWKSGPPELRKTAP----TLSPEHWKAV 412

Query: 822  SQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEPSNSKVLVS 881
              + P+        S       G    + PS  P +        LSP   + S + +   
Sbjct: 413  PPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWK------LSPDQRKTSPASLDFP 466

Query: 882  GKRKDKASASSSAKKRE---HPRKPKAGDHRRGTARLGLSTVTGKNHPAQARSLVEAPVS 938
              +K     S    K      P+KP   + R+          +G +   +A S +  PV 
Sbjct: 467  ESQKSSRGGSPDLWKSSFFIEPQKPVFPETRK-------PGPSGPSESPKAASDIWKPVL 519

Query: 939  TFPQRSQHRGQSSQHTALPQLLLPKASGPQDQPEAGRRASDILTPRHCKHCPWAHMEKYL 998
            +         +  +    P+   P  + P   PEA +RA   L P   KH  +  + K  
Sbjct: 520  SIDT------EPRKPALFPE---PAKTAPPASPEARKRA---LFPEPRKHALFPELPKSA 567

Query: 999  SFPTLKASLTRG 1010
             F   + ++  G
Sbjct: 568  LFSESQKAVELG 579


>gi|91206406 hypothetical protein LOC642265 [Homo sapiens]
          Length = 1347

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 74/278 (26%), Positives = 112/278 (40%), Gaps = 54/278 (19%)

Query: 145 SQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVF-FNKLAFLPRSNLLLPQYHSSAQ 203
           SQLFWGLPSLHSESL    +++   +   +++ S  F FN++     SN+   Q  +   
Sbjct: 413 SQLFWGLPSLHSESL----VANAWVTDRSYTLQSPPFLFNEM-----SNVCPIQRET--- 460

Query: 204 FSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGT 263
                  TM  L   A  P  L P   P +SS     RP P+        A+A  Q+   
Sbjct: 461 -------TMSPLLFQAQPPSHLGPECQPFISS-TPQFRPTPM--------AQAEAQAHLQ 504

Query: 264 SPLEVL-PGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWG 322
           S   VL P + + ++ TG            P       +LS P    PE  L + +   G
Sbjct: 505 SSFPVLSPAFPSLIKNTG---------VACPASQNKVQALSLPETQHPEWPL-LRRQLEG 554

Query: 323 TVGYREKPQASESSMPVPCP--PLDSLPELQRESSLEDP------SRYKPQWECRENSGN 374
            +    + Q S+    V  P  P +SL  +  E+    P       ++  +W   ++ GN
Sbjct: 555 RLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKW-IIQHWGN 613

Query: 375 LWAFES--PVLDLNPELSGTSPECVPPASETPWKGMQS 410
           L   +    ++ L  E  GTS     P   +PW+   S
Sbjct: 614 LGRIQESLDLMQLRDESPGTSQAKGKP---SPWQSSMS 648


>gi|169207217 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2790

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 83/356 (23%), Positives = 123/356 (34%), Gaps = 57/356 (16%)

Query: 46   QKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIP 105
            ++ E EEE EEEE  E++    P  P  P  E P GE+ + A    + G E        P
Sbjct: 1924 ERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKE--------P 1975

Query: 106  EQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLS 165
            E+      SPS +    Q   SF  +  + S  R     S      PS   + L+   L 
Sbjct: 1976 EEKATP--SPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSL----QPSAPPQLLDLPLLV 2029

Query: 166  SGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLL 225
             G  +PL             A  P     L + H     S  G+      EG  P  + L
Sbjct: 2030 FGERNPL-----------VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRL 2078

Query: 226  PPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMP 285
                 P    +L   R +  D        +  ++  G     V   ++    T   ++  
Sbjct: 2079 RTTILPEQLEIL--YRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ---NTRARERKG 2133

Query: 286  QAFEPP--MPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREK-------------- 329
            Q    P  +P P   P + + P  + P+  L + K   GT     K              
Sbjct: 2134 QFRSTPGGVPSPAVKPPATATPASL-PKFNLLLGKVDDGTGREAPKREAPAFPYPTATLA 2192

Query: 330  -------PQASESSMPVPCPPLDSL--PELQRESSLEDPSRYKPQWE-CRENSGNL 375
                   P   E++ P P PPL  L  P    E   E+P +  P+ E C  ++G+L
Sbjct: 2193 SGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDL 2248


>gi|169207592 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 83/356 (23%), Positives = 123/356 (34%), Gaps = 57/356 (16%)

Query: 46   QKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIP 105
            ++ E EEE EEEE  E++    P  P  P  E P GE+ + A    + G E        P
Sbjct: 1840 ERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKE--------P 1891

Query: 106  EQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLS 165
            E+      SPS +    Q   SF  +  + S  R     S      PS   + L+   L 
Sbjct: 1892 EEKATP--SPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSL----QPSAPPQLLDLPLLV 1945

Query: 166  SGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLL 225
             G  +PL             A  P     L + H     S  G+      EG  P  + L
Sbjct: 1946 FGERNPL-----------VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRL 1994

Query: 226  PPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMP 285
                 P    +L   R +  D        +  ++  G     V   ++    T   ++  
Sbjct: 1995 RTTILPEQLEIL--YRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ---NTRARERKG 2049

Query: 286  QAFEPP--MPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREK-------------- 329
            Q    P  +P P   P + + P  + P+  L + K   GT     K              
Sbjct: 2050 QFRSTPGGVPSPAVKPPATATPASL-PKFNLLLGKVDDGTGREAPKREAPAFPYPTATLA 2108

Query: 330  -------PQASESSMPVPCPPLDSL--PELQRESSLEDPSRYKPQWE-CRENSGNL 375
                   P   E++ P P PPL  L  P    E   E+P +  P+ E C  ++G+L
Sbjct: 2109 SGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDL 2164


>gi|169207014 PREDICTED: zinc finger homeobox 2 [Homo sapiens]
          Length = 2706

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 83/356 (23%), Positives = 123/356 (34%), Gaps = 57/356 (16%)

Query: 46   QKSEVEEEGEEEEEGEDEASLDPLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIP 105
            ++ E EEE EEEE  E++    P  P  P  E P GE+ + A    + G E        P
Sbjct: 1840 ERGEEEEEVEEEEVEEEQGLEPPAGPEGPLPEPPDGEELSQAEATKAGGKE--------P 1891

Query: 106  EQTVMQPVSPSRSFPIFQILTSFPVRHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLS 165
            E+      SPS +    Q   SF  +  + S  R     S      PS   + L+   L 
Sbjct: 1892 EEKATP--SPSPAHTCDQCAISFSSQDLLTSHRRLHFLPSL----QPSAPPQLLDLPLLV 1945

Query: 166  SGGPSPLKWSVCSSVFFNKLAFLPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLL 225
             G  +PL             A  P     L + H     S  G+      EG  P  + L
Sbjct: 1946 FGERNPL-----------VAATSPMPGPPLKRKHEDGSLSPTGSEAGGGGEGEPPRDKRL 1994

Query: 226  PPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMP 285
                 P    +L   R +  D        +  ++  G     V   ++    T   ++  
Sbjct: 1995 RTTILPEQLEIL--YRWYMQDSNPTRKMLDCISEEVGLKKRVVQVWFQ---NTRARERKG 2049

Query: 286  QAFEPP--MPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREK-------------- 329
            Q    P  +P P   P + + P  + P+  L + K   GT     K              
Sbjct: 2050 QFRSTPGGVPSPAVKPPATATPASL-PKFNLLLGKVDDGTGREAPKREAPAFPYPTATLA 2108

Query: 330  -------PQASESSMPVPCPPLDSL--PELQRESSLEDPSRYKPQWE-CRENSGNL 375
                   P   E++ P P PPL  L  P    E   E+P +  P+ E C  ++G+L
Sbjct: 2109 SGPQPFLPPGKEATTPTPEPPLPLLPPPPPSEEEGPEEPPKASPESEACSLSAGDL 2164


>gi|146231958 hypothetical protein LOC647060 [Homo sapiens]
          Length = 1347

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 74/278 (26%), Positives = 112/278 (40%), Gaps = 54/278 (19%)

Query: 145 SQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVF-FNKLAFLPRSNLLLPQYHSSAQ 203
           SQLFWGLPSLHSESL    +++   +   +++ S  F FN++     SN+   Q  +   
Sbjct: 413 SQLFWGLPSLHSESL----VANAWVTDRSYTLQSPPFLFNEM-----SNVCPIQRET--- 460

Query: 204 FSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGT 263
                  TM  L   A  P  L P   P +SS     RP P+        A+A  Q+   
Sbjct: 461 -------TMSPLLFQAQPPSHLGPECQPFISS-TPQFRPTPM--------AQAEAQAHLQ 504

Query: 264 SPLEVL-PGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWG 322
           S   VL P + + ++ TG            P       +LS P    PE  L + +   G
Sbjct: 505 SSFPVLSPAFPSLIKNTG---------VACPASQNKVQALSLPETQHPEWPL-LRRQLEG 554

Query: 323 TVGYREKPQASESSMPVPCP--PLDSLPELQRESSLEDP------SRYKPQWECRENSGN 374
            +    + Q S+    V  P  P +SL  +  E+    P       ++  +W   ++ GN
Sbjct: 555 RLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKW-IIQHWGN 613

Query: 375 LWAFES--PVLDLNPELSGTSPECVPPASETPWKGMQS 410
           L   +    ++ L  E  GTS     P   +PW+   S
Sbjct: 614 LGRIQESLDLMQLRDESPGTSQAKGKP---SPWQSSMS 648


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 143/646 (22%), Positives = 221/646 (34%), Gaps = 138/646 (21%)

Query: 291  PMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPEL 350
            P PPP   P  +   R + P     + K    TV     P+A    +PV  PP    PEL
Sbjct: 981  PDPPPRPKPVKMKVNRMLQP-----VPKQEGRTVVVVNNPRAPLGPVPVRPPPG---PEL 1032

Query: 351  QRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQS 410
              + +     +  P         +L    SP            P  +P +          
Sbjct: 1033 SAQPTPGPVPQVLP--------ASLMVSASPA----------GPPLIPASRP-------- 1066

Query: 411  RENIWVPADPVSPPSLPSVPLLESLVMGPQGVLS-ESKALWETMGQKENLWASDSPDPVH 469
                  P   + PP  P+   L  ++  P GVLS  S+    T+  K    A     P  
Sbjct: 1067 ------PGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAP 1120

Query: 470  STPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSPSLALSPPPA-----LAPEL 524
                ++L++P  + PG     + AT   T     ++A+ + +   +P PA     L+P++
Sbjct: 1121 PPGSSSLLKPLTVPPGYTFPPAAATTTST-----TTATATTTAVPAPTPAPQRLILSPDM 1175

Query: 525  -LRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQD---LHGASPLGVLSDSQSIVG 580
              R+ S  V+S  +      +   N+  SK     +  +   L GA         Q  VG
Sbjct: 1176 QARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQV------RQLAVG 1229

Query: 581  EMEQ-KENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPA 639
            +    + N V +    G     +  +   + + +A      P    V    +   +  PA
Sbjct: 1230 QPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTP----VSVLPSSTPSTTPA 1285

Query: 640  PSSLSTPLPEPHIDLELVWRN----VQQREVPQ-GPSPLAVDPLHPVPQPPTLAEAVKIE 694
            P+ LS PL    +   +V       +  R+ P+ G +P  V PL P P+PP+      + 
Sbjct: 1286 PTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTP--VPPLAPAPRPPSSGLPAVLN 1343

Query: 695  RTHPGLPKGVTCPGV-KAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPA-- 751
                  P  +  P +  A AP+     V  LL                   KL  SP+  
Sbjct: 1344 PRPTLTPGRLPTPTLGTARAPMPTPTLVRPLL-------------------KLVHSPSPE 1384

Query: 752  --SRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPPNPCPHS--------------- 794
              + APG +    SSP+          +PS  P     P P P+S               
Sbjct: 1385 VSASAPGAAPLTISSPL---------HVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPL 1435

Query: 795  SSCHPQEVQRTVPQPVQSSHCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQG 854
            SS  P  V  T+P P  +        S+ L    SG A             + S  P   
Sbjct: 1436 SSSLPISVPTTLPAPASAPLT--IPISAPLTVSASGPA------------LLTSVTPPLA 1481

Query: 855  PCVHMEAGVDYLSPGPGEPSNSKVLVSGKRKDKASASSSAKKREHP 900
            P V    G   L+P    PS S + +       A + SS++   HP
Sbjct: 1482 PVVPAAPGPPSLAPSGASPSASALTLG---LATAPSLSSSQTPGHP 1524



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 156/711 (21%), Positives = 243/711 (34%), Gaps = 124/711 (17%)

Query: 68   PLKPCSPTKEAPTGEQATPAPPQPSCGSEGLLKAIGIPEQTVMQPVSPSRSFPIFQILTS 127
            P     PT  AP   + +PAPP    GS  LLK + +P      P + + +       T+
Sbjct: 1102 PTLSLKPTPPAPV--RLSPAPPP---GSSSLLKPLTVPPGYTFPPAAATTTSTTTATATT 1156

Query: 128  FPV-------RHKIASGNRQQQRKSQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSV 180
              V       +  I S + Q +  S     +  L S +   +  ++GG  PL + +    
Sbjct: 1157 TAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPV-ANAGGSKPLTFQIQG-- 1213

Query: 181  FFNKLAF---------------LPRSNLLLPQYHSSAQFSTHGAHTMEDLEGMAPDPQLL 225
              NKL                 L R+ + L          +  AH +  ++ +AP P   
Sbjct: 1214 --NKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAH-VALIQAVAPTPGPT 1270

Query: 226  P----PPSSPSVSSLLLHLRPFPVDHKGVLSGAEA-PTQSPGTSPLEVLPGYETHLETTG 280
            P    P S+PS +       P P      L+  +  PT    T  ++++           
Sbjct: 1271 PVSVLPSSTPSTT-------PAPTGLSLPLAANQVPPTMVNNTGVVKIVV---------- 1313

Query: 281  HKKMPQAFEPPMPP--PCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMP 338
             ++ P+    P+PP  P   P S   P  ++P   L        T G    P    +  P
Sbjct: 1314 -RQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTL--------TPGRLPTPTLGTARAP 1364

Query: 339  VPCPPLDSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSG--TSPEC 396
            +P P L   P L+    +  PS   P+              SP L +   L G  +SP  
Sbjct: 1365 MPTPTL-VRPLLK---LVHSPS---PEVSASAPGAAPLTISSP-LHVPSSLPGPASSPMP 1416

Query: 397  VP-------PASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKAL 449
            +P       P S T    + S   I VP    +P S P    L   +  P  V +   AL
Sbjct: 1417 IPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAP----LTIPISAPLTVSASGPAL 1472

Query: 450  WETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHS--RNSSAS 507
              ++          +P P    P         +  G   A S ++ +   H      ++S
Sbjct: 1473 LTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSS 1532

Query: 508  RSPSLALSPPPALAPELLRVRSM---------------GVLSDSEARCGDIQKTKNSWAS 552
              P L  +  PA +P L+   ++                +L+ + +    +       A+
Sbjct: 1533 HVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAA 1592

Query: 553  KHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEP 612
               A   P      +PL VL+ S      +   +  VPV     S+P ++  S S V  P
Sbjct: 1593 PQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVM-APSSTPGTSLASASPVPAP 1651

Query: 613  ---IADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQ-----R 664
               +A  S        V        + LP+P+S  T    P +   L   +  Q      
Sbjct: 1652 TPVLAPSSTQTMLPAPV-------PSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGT 1704

Query: 665  EVPQGPSPLAVDPLHPVPQ-PPTLAEAVKIERTHPGLPKGVTCPGVKAEAP 714
              PQGP P     L P     PT A+ + +    PG P G T     A AP
Sbjct: 1705 GNPQGPFPTQTLSLTPASSLVPTPAQTLSLA---PGPPLGPTQTLSLAPAP 1752



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 78/312 (25%), Positives = 106/312 (33%), Gaps = 57/312 (18%)

Query: 222  PQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAE---APTQS--PGTSPLEVLPGYETHL 276
            P L P  +SPS S+L L L   P        G     APT S  PG +   V P     L
Sbjct: 1491 PSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNS-TVAPACSPVL 1549

Query: 277  ETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESS 336
                    P    P  P P  + ASL  P         + S+     +     PQ +  +
Sbjct: 1550 VPASALASP---FPSAPNPAPAQASLLAPAS-------SASQALATPLAPMAAPQTAILA 1599

Query: 337  MPVPCPPLDSLPELQRESS----LEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGT 392
             P P PPL  LP L         L       P        G   A  SPV    P L+ +
Sbjct: 1600 -PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPS 1658

Query: 393  SPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMGPQGVLSESKALWET 452
            S + + PA                   PV P  LPS    ++L + P        AL  T
Sbjct: 1659 STQTMLPA-------------------PV-PSPLPSPASTQTLALAP--------ALAPT 1690

Query: 453  MG--QKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSEATWKDTEHSRNSSASRSP 510
            +G        +  + +P    P  TL     + P   L  + A  +    +       + 
Sbjct: 1691 LGGSSPSQTLSLGTGNPQGPFPTQTL----SLTPASSLVPTPA--QTLSLAPGPPLGPTQ 1744

Query: 511  SLALSPPPALAP 522
            +L+L+P P LAP
Sbjct: 1745 TLSLAPAPPLAP 1756



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 135/609 (22%), Positives = 189/609 (31%), Gaps = 154/609 (25%)

Query: 220  PDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHLETT 279
            P P   P P+  S  + +  L P PV          AP      +P+ +LP    H+   
Sbjct: 2437 PRPAPRPRPTPASAPAAIPALVPVPVS---------APVPISAPNPITILP---VHI--- 2481

Query: 280  GHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWGTVGYREKPQASESSMPV 339
                +P    P   PPC SPA    P    P                   P  +++ +  
Sbjct: 2482 ----LPSPPPPSQIPPCSSPACTPPPACTPPPA---------------HTPPPAQTCLVT 2522

Query: 340  PCPPL----DSLPELQRESSLEDPSRYKPQWECRENSGNLWAFESPVLDLNPELSGTSPE 395
            P  PL     S+P     ++L  P   +P+ E    +  L + ES  L        +S  
Sbjct: 2523 PSSPLLLGPPSVPISASVTNL--PLGLRPEAELCAQA--LASPESLELASVASSETSSLS 2578

Query: 396  CVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMG----PQGVLSESKALWE 451
             VPP    P         + V   PVS  +L   P   SL +     P G   E+    E
Sbjct: 2579 LVPPKDLLP---------VAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAE 2629

Query: 452  -----TMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLATSE-------------- 492
                  + + E L    S       PP+   +     P E   TSE              
Sbjct: 2630 GTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEK 2689

Query: 493  ----ATWKDTEHSRNSSASRSPSLALSPPPALAPELLRVRSMGVLSDSEARCGDIQKTKN 548
                 T +    S +SSA+ SP     P PA  P       + +      R G       
Sbjct: 2690 PQELVTAEVAAPSTSSSATSSPE---GPSPARPPRRRTSADVEIRGQGTGRPG------- 2739

Query: 549  SWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPG------RGSSPSSN 602
                + P   + + L G   + V+ + + +    +Q+     + PG         SPS  
Sbjct: 2740 ----QPPGPKVLRKLPGRL-VTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVR 2794

Query: 603  SVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQ 662
            S+S    S PI       P                   SSL TP  +P I      R   
Sbjct: 2795 SMSGPESSPPIGGPCEAAPS------------------SSLPTPPQQPFIA-----RRHI 2831

Query: 663  QREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVP 722
            +  V  G SP   D       PP    AVK  R  P  PK    P               
Sbjct: 2832 ELGVTGGGSPENGDGALLAITPP----AVKRRRGRP--PKKNRSPA-------------- 2871

Query: 723  ELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILS-STIPDFWGLPSCP 781
                     A +   E      K + + A   PGP     + P+L    IP   G     
Sbjct: 2872 --------DAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIP---GPQPLG 2920

Query: 782  PQQIYPPNP 790
            PQ ++ PNP
Sbjct: 2921 PQPVHRPNP 2929


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 78/328 (23%), Positives = 113/328 (34%), Gaps = 55/328 (16%)

Query: 208 GAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGTSPLE 267
           G+ T++      P P L P  + P  +   L L P        L    +P  SP  SPL 
Sbjct: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP--------LQAPPSPPASPPLSPLA 382

Query: 268 VLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEG--------GLAISKD 319
             P  +       H  +   F PP  PP Q+P S      VSP           LA +  
Sbjct: 383 T-PSPQAPNALAVHL-LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA-APP 439

Query: 320 FWGTVGYREKPQASESSMPVP--CPPLDSLP-ELQRESSLEDPSRYKPQWECRENSGNLW 376
                     P  S S+ P P   PPL + P +L +      P+   P  +   +    +
Sbjct: 440 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 499

Query: 377 AFESPVLDLNPELS-GTSPECVPPASETPWKGMQSRENIWVPADPVSPPSL-----PSVP 430
             ++P    +P  S   SP   PP    P   + +   + VP  P + P+L     P  P
Sbjct: 500 PGQAP---FSPSASLPMSPLATPPPQAPP---VLAAPLLQVPPSPPASPTLQAPRRPPTP 553

Query: 431 LLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRINPGECLAT 490
             ++ V GP+  L+                A   P P   +P +TL  P      +    
Sbjct: 554 GPDTSVSGPRLTLA---------------LAPGPPPPPSRSPSSTLSGP------DLAGH 592

Query: 491 SEATWKDTEHSRNSSASRSPSLALSPPP 518
           S +     E  R   +      A SPPP
Sbjct: 593 SSSATSTPEELRGYDSGPEGGAAASPPP 620



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 72/295 (24%), Positives = 92/295 (31%), Gaps = 64/295 (21%)

Query: 249 GVLSGAEAPTQSPGTSPLEVLPGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKV 308
           G LS +   T SP   P    P     L+T     +P    PP  PP Q+  SL  P   
Sbjct: 288 GPLSSSPLATPSPSAPPS---PSAPPSLQT-----LPS---PPATPPSQATTSLGSP--- 333

Query: 309 SPEGGLAISKDFWGTVGYREKPQASESSMPVP-CPPLDSLPELQRESSLEDPSRYKPQWE 367
                         T  +   P  S  + P P  PP  +LP LQ   S        P   
Sbjct: 334 ----------TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT 383

Query: 368 CRENSGNLWAFESPVLDLNPELSGT-----SPECVPPASETPWKGMQSRENIWVPADPVS 422
               + N  A        +P  S       SP   PP S +     Q+  ++  P   V 
Sbjct: 384 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443

Query: 423 PPSLPSVPLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPHRI 482
           P    S P+  S    PQ                       +P P+ + PP  L +P   
Sbjct: 444 PSPPASPPMSPSATPPPQ-----------------------APPPL-AAPPLQLAKPPPQ 479

Query: 483 NPGECLATSEATWKDTEHSRNSSASRSP--SLALSP--------PPALAPELLRV 527
            P                S    A  SP  SL +SP        PP LA  LL+V
Sbjct: 480 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 81/372 (21%), Positives = 108/372 (29%), Gaps = 49/372 (13%)

Query: 463 DSPDPVHSTPPTTLMEPHRINPGEC----LATSEATWKDTEHSRNSSASRSPSLALSPPP 518
           D+  P   TP   +    R    E      A S      TE  R S +S S      P P
Sbjct: 154 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 213

Query: 519 ALA-----------PELLRVRSMGVLSDSEARCGDIQKTKNSWASKHPACNLPQDLHGAS 567
           A             P    + S      S AR G   +     A  HP+   P+ L    
Sbjct: 214 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR-APAHPSQPKPKGLQALR 272

Query: 568 PLGVL---SDSQSIVGEMEQKENCVPVFPGRGSSPSSNSVSKSHVSEPIADQSNYKPDGE 624
           P  V     D+   +G +       P  P    SPS+    ++  S P    S       
Sbjct: 273 PPQVTPPRKDAAPALGPLSSSPLATPS-PSAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331

Query: 625 AVEQRKNHWATELPAPSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQP 684
           +   +  H     P  S L+TP                    PQ P  LA+ PL   P P
Sbjct: 332 SPTLQATHSFLPSPPLSPLATP-------------------PPQAPPALALPPLQAPPSP 372

Query: 685 PTLAEAVKIERTHPGLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLK 744
           P       +    P  P  +    ++A         V    + P       S  +     
Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA------SPPVSPSAT 426

Query: 745 KLRQSPASRAPGPSQSFCSSPILSSTIPDFWGLPSCPPQQIYPP----NPCPHSSSCHPQ 800
              Q+P S A  P Q   S P      P     P  PP    PP     P P +      
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486

Query: 801 EVQRTVPQPVQS 812
              + +P P  S
Sbjct: 487 PPLQALPSPPAS 498


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 130/602 (21%), Positives = 182/602 (30%), Gaps = 134/602 (22%)

Query: 199  HSSAQFSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKG--VLSGAEA 256
            HS A    H AH +         P L   P S +  SL    +P P       VL G   
Sbjct: 533  HSGA----HSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTL 588

Query: 257  PTQSPGT-SPLEVLPGYETHLETTGHK----------KMPQAFEPPMPPPCQSPASLSEP 305
            P  +    +  + L    T    TG            + P A   P+P   Q P +   P
Sbjct: 589  PPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPP 648

Query: 306  RKVSPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQ 365
            +  +P+                  PQA   + P P P L S PE   +  L  P    P 
Sbjct: 649  QAPTPQAA--------------APPQA---TTPQPSPGLASSPE---KIVLGQPPSATPT 688

Query: 366  WECRENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPS 425
                ++S  ++    P       LS   P    PAS            + V A P +   
Sbjct: 689  AILTQDSLQMFL---PQERSQQPLSAEGPHLSVPAS------------VIVSAPPPAQDP 733

Query: 426  LPSVPLLESLVMGPQGVLSESKAL----WETMGQKENLWASDSPDPVHSTP---PTTLME 478
             P+ P+ +   +GPQ   S++              +    S SP   H  P      L  
Sbjct: 734  APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPS 793

Query: 479  PHRINPGECLATSEATWKDTEHSRNSSASRSPS---LALSPPPALAPELLRVRSMGVLSD 535
            PH   P                SR  S SR PS   L   PPP   P L           
Sbjct: 794  PHPTRP-----------PSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTL----------- 831

Query: 536  SEARCGDIQKTKNSWASKHPACNLPQDLHGASPLGVLSDSQSIVGEMEQKENCVPVFPGR 595
                   I   +N      PA N      G     +   SQ   G +    +  P     
Sbjct: 832  -----PGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSS 886

Query: 596  GSSPSSNSVSKSHVSEPIADQSNYKPDGEAVEQRKNHWATELPAPSSLSTPLPEPHIDLE 655
              + SS + S+     P   Q  + P                  P    TP P  H+   
Sbjct: 887  AVASSSETSSRLPAPTPSDFQLQFPPS---------------QGPHKSPTPPPTLHL--- 928

Query: 656  LVWRNVQQREVPQGPSP----LAVDPLHPVPQPPTLAEAVKIERTHPGLPKGVTCPGVKA 711
                 V +   P  P P    +   P   +PQP  L     +ER H  +P G+       
Sbjct: 929  -----VPEPAAPPPPPPRTFQMVTTPFPALPQPKAL-----LERFHQ-VPSGIILQNKAG 977

Query: 712  EAPLS-QRWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPSQSFCSSPILSST 770
             AP + Q  T    LT P              +    Q+P+     PS +   +P+ ++ 
Sbjct: 978  GAPAAPQTSTSLGPLTSPA-----------ASVLVSGQAPSGTPTAPSHAPAPAPMAATG 1026

Query: 771  IP 772
            +P
Sbjct: 1027 LP 1028



 Score = 31.6 bits (70), Expect = 4.0
 Identities = 44/196 (22%), Positives = 69/196 (35%), Gaps = 13/196 (6%)

Query: 639 APSSLSTPLPEPHIDLELVWRNVQQREVPQGPSPLAVDPLHPVPQPPTLAEAVKIERTHP 698
           AP ++STPLP       L  +  Q ++ PQ P+P A  P       P+   A   E+   
Sbjct: 627 APPAVSTPLP-------LGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVL 679

Query: 699 GLPKGVTCPGVKAEAPLSQRWTVPELLTHPGIHAWQWSRELKLRLKKLRQSPASRAPGPS 758
           G P   T   +  +  L  +  +P+  +   + A      +   +  +   P ++ P P+
Sbjct: 680 GQPPSATPTAILTQDSL--QMFLPQERSQQPLSAEGPHLSVPASV-IVSAPPPAQDPAPA 736

Query: 759 QSFCSSPILSSTIPDFWGLPSCPPQ---QIYPPNPCPHSSSCHPQEVQRTVPQPVQSSHC 815
                   L    PD    P+  PQ         P P SS   P +        + S H 
Sbjct: 737 TPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHP 796

Query: 816 HHFQSSSQLQPQESGR 831
               S    +PQ   R
Sbjct: 797 TRPPSRPPSRPQSVSR 812


>gi|55953110 retinoblastoma protein-binding zinc finger protein
           isoform c [Homo sapiens]
          Length = 1481

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 71/288 (24%), Positives = 111/288 (38%), Gaps = 53/288 (18%)

Query: 252 SGAEAPTQSPGTSPLEVLPGYETHLETTGHKKM---PQAFEPPMPPPCQSPASLSEPRKV 308
           SG +   +  G +P++    +E+ L+ + HKK     +  E       Q   S  + RK 
Sbjct: 627 SGVKQKAEGTGKTPVQ----WESVLDLSVHKKHCSDSEGKEFKESHSVQPTCSAVKKRKP 682

Query: 309 SPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWEC 368
           +      +  + +  +    +  A  +  P PC  L++ P         DP       + 
Sbjct: 683 TTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQP---------DP-------DL 726

Query: 369 RENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPS 428
              SG    F +P ++  P++  +SP     A +TP         + +P DP SPP  P 
Sbjct: 727 GPGSG----FPAPTVESTPDVCPSSP-----ALQTPSLSSGQLPPLLIPTDPSSPPPCPP 777

Query: 429 V--------PLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPH 480
           V        PLL ++   P    S S +         N  A  SP P+ S  PT    P 
Sbjct: 778 VLTVATPPPPLLPTV---PLPAPSSSASPHPCPSPLSNATA-QSPLPILS--PTVSPSPS 831

Query: 481 RINPGECLATSEATWKDTEHSRNSSASRSPSLAL-------SPPPALA 521
            I P E L ++ +    T  S +SS+S S S +        SPPP  A
Sbjct: 832 PIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSA 879



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 41/141 (29%), Positives = 56/141 (39%), Gaps = 17/141 (12%)

Query: 757 PSQSFCSSPILSS-TIPDFWGLPSCPPQQIYPPNPCPH--SSSCHPQEVQRTVPQPVQSS 813
           PS     +P LSS  +P     P   P     P PCP   + +  P  +  TVP P  SS
Sbjct: 745 PSSPALQTPSLSSGQLP-----PLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSS 799

Query: 814 HCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEP 873
                  S+   P  S  +   +Q    +    VS  PS  P   +E  +   SPGP   
Sbjct: 800 -------SASPHPCPSPLSNATAQSPLPILSPTVS--PSPSPIPPVEPLMSAASPGPPTL 850

Query: 874 SNSKVLVSGKRKDKASASSSA 894
           S+S    S      +S+SSS+
Sbjct: 851 SSSSSSSSSSSSFSSSSSSSS 871


>gi|20336260 retinoblastoma protein-binding zinc finger protein
            isoform b [Homo sapiens]
          Length = 1682

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 71/288 (24%), Positives = 111/288 (38%), Gaps = 53/288 (18%)

Query: 252  SGAEAPTQSPGTSPLEVLPGYETHLETTGHKKM---PQAFEPPMPPPCQSPASLSEPRKV 308
            SG +   +  G +P++    +E+ L+ + HKK     +  E       Q   S  + RK 
Sbjct: 828  SGVKQKAEGTGKTPVQ----WESVLDLSVHKKHCSDSEGKEFKESHSVQPTCSAVKKRKP 883

Query: 309  SPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWEC 368
            +      +  + +  +    +  A  +  P PC  L++ P         DP       + 
Sbjct: 884  TTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQP---------DP-------DL 927

Query: 369  RENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPS 428
               SG    F +P ++  P++  +SP     A +TP         + +P DP SPP  P 
Sbjct: 928  GPGSG----FPAPTVESTPDVCPSSP-----ALQTPSLSSGQLPPLLIPTDPSSPPPCPP 978

Query: 429  V--------PLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPH 480
            V        PLL ++   P    S S +         N  A  SP P+ S  PT    P 
Sbjct: 979  VLTVATPPPPLLPTV---PLPAPSSSASPHPCPSPLSNATA-QSPLPILS--PTVSPSPS 1032

Query: 481  RINPGECLATSEATWKDTEHSRNSSASRSPSLAL-------SPPPALA 521
             I P E L ++ +    T  S +SS+S S S +        SPPP  A
Sbjct: 1033 PIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSA 1080



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 41/141 (29%), Positives = 56/141 (39%), Gaps = 17/141 (12%)

Query: 757  PSQSFCSSPILSS-TIPDFWGLPSCPPQQIYPPNPCPH--SSSCHPQEVQRTVPQPVQSS 813
            PS     +P LSS  +P     P   P     P PCP   + +  P  +  TVP P  SS
Sbjct: 946  PSSPALQTPSLSSGQLP-----PLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSS 1000

Query: 814  HCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEP 873
                   S+   P  S  +   +Q    +    VS  PS  P   +E  +   SPGP   
Sbjct: 1001 -------SASPHPCPSPLSNATAQSPLPILSPTVS--PSPSPIPPVEPLMSAASPGPPTL 1051

Query: 874  SNSKVLVSGKRKDKASASSSA 894
            S+S    S      +S+SSS+
Sbjct: 1052 SSSSSSSSSSSSFSSSSSSSS 1072


>gi|20336258 retinoblastoma protein-binding zinc finger protein
            isoform a [Homo sapiens]
          Length = 1718

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 71/288 (24%), Positives = 111/288 (38%), Gaps = 53/288 (18%)

Query: 252  SGAEAPTQSPGTSPLEVLPGYETHLETTGHKKM---PQAFEPPMPPPCQSPASLSEPRKV 308
            SG +   +  G +P++    +E+ L+ + HKK     +  E       Q   S  + RK 
Sbjct: 828  SGVKQKAEGTGKTPVQ----WESVLDLSVHKKHCSDSEGKEFKESHSVQPTCSAVKKRKP 883

Query: 309  SPEGGLAISKDFWGTVGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWEC 368
            +      +  + +  +    +  A  +  P PC  L++ P         DP       + 
Sbjct: 884  TTCMLQKVLLNEYNGIDLPVENPADGTRSPSPCKSLEAQP---------DP-------DL 927

Query: 369  RENSGNLWAFESPVLDLNPELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPS 428
               SG    F +P ++  P++  +SP     A +TP         + +P DP SPP  P 
Sbjct: 928  GPGSG----FPAPTVESTPDVCPSSP-----ALQTPSLSSGQLPPLLIPTDPSSPPPCPP 978

Query: 429  V--------PLLESLVMGPQGVLSESKALWETMGQKENLWASDSPDPVHSTPPTTLMEPH 480
            V        PLL ++   P    S S +         N  A  SP P+ S  PT    P 
Sbjct: 979  VLTVATPPPPLLPTV---PLPAPSSSASPHPCPSPLSNATA-QSPLPILS--PTVSPSPS 1032

Query: 481  RINPGECLATSEATWKDTEHSRNSSASRSPSLAL-------SPPPALA 521
             I P E L ++ +    T  S +SS+S S S +        SPPP  A
Sbjct: 1033 PIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSA 1080



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 41/141 (29%), Positives = 56/141 (39%), Gaps = 17/141 (12%)

Query: 757  PSQSFCSSPILSS-TIPDFWGLPSCPPQQIYPPNPCPH--SSSCHPQEVQRTVPQPVQSS 813
            PS     +P LSS  +P     P   P     P PCP   + +  P  +  TVP P  SS
Sbjct: 946  PSSPALQTPSLSSGQLP-----PLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSS 1000

Query: 814  HCHHFQSSSQLQPQESGRAEQGSQRGEKMKGKMVSQVPSQGPCVHMEAGVDYLSPGPGEP 873
                   S+   P  S  +   +Q    +    VS  PS  P   +E  +   SPGP   
Sbjct: 1001 -------SASPHPCPSPLSNATAQSPLPILSPTVS--PSPSPIPPVEPLMSAASPGPPTL 1051

Query: 874  SNSKVLVSGKRKDKASASSSA 894
            S+S    S      +S+SSS+
Sbjct: 1052 SSSSSSSSSSSSFSSSSSSSS 1072


>gi|169174618 PREDICTED: family with sequence similarity 75, member
           A4 isoform 2 [Homo sapiens]
          Length = 1272

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 73/278 (26%), Positives = 111/278 (39%), Gaps = 54/278 (19%)

Query: 145 SQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVF-FNKLAFLPRSNLLLPQYHSSAQ 203
           SQLFWGLPSLHSESL    +++   +   +++ S  F FN++     SN+   Q  +   
Sbjct: 338 SQLFWGLPSLHSESL----VANAWVTDRSYTLQSPPFLFNEM-----SNVCPIQRET--- 385

Query: 204 FSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGT 263
                  TM  L   A     L P   P +SS     RP P+        A+A  Q+   
Sbjct: 386 -------TMSPLLFQAQPLSHLGPECQPFISS-TPQFRPTPM--------AQAEAQAHLQ 429

Query: 264 SPLEVL-PGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWG 322
           S   VL P + + ++ TG            P       +LS P    PE  L + +   G
Sbjct: 430 SSFPVLSPAFPSLIQNTG---------VACPASQNKVQALSLPETQHPEWPL-LRRQLEG 479

Query: 323 TVGYREKPQASESSMPVPCP--PLDSLPELQRESSLEDP------SRYKPQWECRENSGN 374
            +    + Q S+    V  P  P +SL  +  E+    P       ++  +W   ++ GN
Sbjct: 480 RLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKW-IIQHWGN 538

Query: 375 LWAFES--PVLDLNPELSGTSPECVPPASETPWKGMQS 410
           L   +    ++ L  E  GTS     P   +PW+   S
Sbjct: 539 LGRIQESLDLMQLRDESPGTSQAKGKP---SPWQSSMS 573


>gi|239743732 PREDICTED: family with sequence similarity 75, member
           A4 isoform 1 [Homo sapiens]
          Length = 1361

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 73/278 (26%), Positives = 111/278 (39%), Gaps = 54/278 (19%)

Query: 145 SQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVF-FNKLAFLPRSNLLLPQYHSSAQ 203
           SQLFWGLPSLHSESL    +++   +   +++ S  F FN++     SN+   Q  +   
Sbjct: 427 SQLFWGLPSLHSESL----VANAWVTDRSYTLQSPPFLFNEM-----SNVCPIQRET--- 474

Query: 204 FSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGT 263
                  TM  L   A     L P   P +SS     RP P+        A+A  Q+   
Sbjct: 475 -------TMSPLLFQAQPLSHLGPECQPFISS-TPQFRPTPM--------AQAEAQAHLQ 518

Query: 264 SPLEVL-PGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWG 322
           S   VL P + + ++ TG            P       +LS P    PE  L + +   G
Sbjct: 519 SSFPVLSPAFPSLIQNTG---------VACPASQNKVQALSLPETQHPEWPL-LRRQLEG 568

Query: 323 TVGYREKPQASESSMPVPCP--PLDSLPELQRESSLEDP------SRYKPQWECRENSGN 374
            +    + Q S+    V  P  P +SL  +  E+    P       ++  +W   ++ GN
Sbjct: 569 RLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKW-IIQHWGN 627

Query: 375 LWAFES--PVLDLNPELSGTSPECVPPASETPWKGMQS 410
           L   +    ++ L  E  GTS     P   +PW+   S
Sbjct: 628 LGRIQESLDLMQLRDESPGTSQAKGKP---SPWQSSMS 662


>gi|153791826 hypothetical protein LOC26165 [Homo sapiens]
          Length = 1347

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 73/278 (26%), Positives = 111/278 (39%), Gaps = 54/278 (19%)

Query: 145 SQLFWGLPSLHSESLEAIFLSSGGPSPLKWSVCSSVF-FNKLAFLPRSNLLLPQYHSSAQ 203
           SQLFWGLPSLHSESL    +++   +   +++ S  F FN++     SN+   Q  +   
Sbjct: 413 SQLFWGLPSLHSESL----VANAWVTDRSYTLQSPPFLFNEM-----SNVCPIQRET--- 460

Query: 204 FSTHGAHTMEDLEGMAPDPQLLPPPSSPSVSSLLLHLRPFPVDHKGVLSGAEAPTQSPGT 263
                  TM  L   A     L P   P +SS     RP P+        A+A  Q+   
Sbjct: 461 -------TMSPLLFQAQPLSHLGPECQPFISS-TPQFRPTPM--------AQAEAQAHLQ 504

Query: 264 SPLEVL-PGYETHLETTGHKKMPQAFEPPMPPPCQSPASLSEPRKVSPEGGLAISKDFWG 322
           S   VL P + + ++ TG            P       +LS P    PE  L + +   G
Sbjct: 505 SSFPVLSPAFPSLIQNTG---------VACPASQNKVQALSLPETQHPEWPL-LRRQLEG 554

Query: 323 TVGYREKPQASESSMPVPCP--PLDSLPELQRESSLEDP------SRYKPQWECRENSGN 374
            +    + Q S+    V  P  P +SL  +  E+    P       ++  +W   ++ GN
Sbjct: 555 RLALPSRVQKSQDVFSVSTPNLPQESLTSILPENFPVSPELRRQLEQHIKKW-IIQHWGN 613

Query: 375 LWAFES--PVLDLNPELSGTSPECVPPASETPWKGMQS 410
           L   +    ++ L  E  GTS     P   +PW+   S
Sbjct: 614 LGRIQESLDLMQLRDESPGTSQAKGKP---SPWQSSMS 648


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 72/259 (27%), Positives = 96/259 (37%), Gaps = 40/259 (15%)

Query: 222  PQLLPPPS--SPSVSSLLLHLR---PFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHL 276
            P + P P+  +P   S  L  R   P P   K  LS    P  SP   PL+  PG +   
Sbjct: 761  PSVTPTPARGTPRSQSFALRARRKGPPPPPPKR-LSSVSGP--SPEPPPLDESPGPKEGA 817

Query: 277  ETTGHKKMPQAF---EPPMPPPCQSPASLSEPRKVSPEG----------GLAISKDFWGT 323
                 + + +     EPP PP    PAS +E  +  PEG          GL  +++   T
Sbjct: 818  TGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLT 877

Query: 324  VGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECREN---SGNLWAFES 380
            +  R KP A       P PP         + +L +    K + +CRE       L AF  
Sbjct: 878  IKQRPKP-AGPPPRETPVPP-------GLDFNLTESDTVKRRPKCREREPLQTALLAFGV 929

Query: 381  PVLDLNP--ELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMG 438
                  P   L   +P   PPAS  P     S     +PA  V  P  PS P ++  V  
Sbjct: 930  ASATPGPAAPLPSPTPGESPPASSLPQPEPSS-----LPAQGVPTPLAPS-PAMQPPVPP 983

Query: 439  PQGVLSESKALWETMGQKE 457
              G   ES A     G+ E
Sbjct: 984  CPGPGLESSAASRWNGETE 1002


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 72/259 (27%), Positives = 96/259 (37%), Gaps = 40/259 (15%)

Query: 222  PQLLPPPS--SPSVSSLLLHLR---PFPVDHKGVLSGAEAPTQSPGTSPLEVLPGYETHL 276
            P + P P+  +P   S  L  R   P P   K  LS    P  SP   PL+  PG +   
Sbjct: 843  PSVTPTPARGTPRSQSFALRARRKGPPPPPPKR-LSSVSGP--SPEPPPLDESPGPKEGA 899

Query: 277  ETTGHKKMPQAF---EPPMPPPCQSPASLSEPRKVSPEG----------GLAISKDFWGT 323
                 + + +     EPP PP    PAS +E  +  PEG          GL  +++   T
Sbjct: 900  TGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLT 959

Query: 324  VGYREKPQASESSMPVPCPPLDSLPELQRESSLEDPSRYKPQWECREN---SGNLWAFES 380
            +  R KP A       P PP         + +L +    K + +CRE       L AF  
Sbjct: 960  IKQRPKP-AGPPPRETPVPP-------GLDFNLTESDTVKRRPKCREREPLQTALLAFGV 1011

Query: 381  PVLDLNP--ELSGTSPECVPPASETPWKGMQSRENIWVPADPVSPPSLPSVPLLESLVMG 438
                  P   L   +P   PPAS  P     S     +PA  V  P  PS P ++  V  
Sbjct: 1012 ASATPGPAAPLPSPTPGESPPASSLPQPEPSS-----LPAQGVPTPLAPS-PAMQPPVPP 1065

Query: 439  PQGVLSESKALWETMGQKE 457
              G   ES A     G+ E
Sbjct: 1066 CPGPGLESSAASRWNGETE 1084


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,402,975
Number of Sequences: 37866
Number of extensions: 3277181
Number of successful extensions: 20058
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 509
Number of HSP's that attempted gapping in prelim test: 17154
Number of HSP's gapped (non-prelim): 3165
length of query: 1031
length of database: 18,247,518
effective HSP length: 112
effective length of query: 919
effective length of database: 14,006,526
effective search space: 12871997394
effective search space used: 12871997394
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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