Guide to the Human Genome
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Search of human proteins with 94536830

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|94536830 DMRT-like family C2 [Homo sapiens]
         (367 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|94536830 DMRT-like family C2 [Homo sapiens]                        785   0.0  
gi|145046253 DMRT-like family C1B [Homo sapiens]                      129   4e-30
gi|116008456 DMRT-like family C1 [Homo sapiens]                       129   4e-30
gi|11056048 doublesex and mab-3 related transcription factor 3 [...   103   2e-22
gi|195947401 doublesex and mab-3 related transcription factor 2 ...    97   2e-20
gi|5729806 doublesex and mab-3 related transcription factor 2 is...    97   2e-20
gi|153945850 doublesex and mab-3 related transcription factor 2 ...    97   2e-20
gi|170763515 DMRT-like family A1 [Homo sapiens]                        87   3e-17
gi|62241026 doublesex and mab-3 related transcription factor 1 [...    86   7e-17
gi|154146231 DMRT-like family A2 [Homo sapiens]                        86   7e-17
gi|24308352 DMRT-like family B with proline-rich C-terminal, 1 [...    74   3e-13
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    60   3e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          57   3e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          57   3e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          57   3e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   3e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    57   3e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   1e-07
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 54   2e-07
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    54   3e-07
gi|41281612 zinc finger protein 828 [Homo sapiens]                     53   4e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     52   6e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni...    52   6e-07
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                52   8e-07
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 52   1e-06
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    51   1e-06
gi|160707881 formin 2 [Homo sapiens]                                   51   1e-06
gi|116284392 mucin 2 precursor [Homo sapiens]                          51   2e-06
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               51   2e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  50   4e-06

>gi|94536830 DMRT-like family C2 [Homo sapiens]
          Length = 367

 Score =  785 bits (2027), Expect = 0.0
 Identities = 367/367 (100%), Positives = 367/367 (100%)

Query: 1   MEPSDMPAGYHCPLDSAPWDETRDPQSTELIPRRAISRSPTCARCRNHGVTAHLKGHKRL 60
           MEPSDMPAGYHCPLDSAPWDETRDPQSTELIPRRAISRSPTCARCRNHGVTAHLKGHKRL
Sbjct: 1   MEPSDMPAGYHCPLDSAPWDETRDPQSTELIPRRAISRSPTCARCRNHGVTAHLKGHKRL 60

Query: 61  CLFQACECHKCVLILERRRVMAAQVALRRQQEAQLKKHLMRRGEASPKAPNHFRKGTTQP 120
           CLFQACECHKCVLILERRRVMAAQVALRRQQEAQLKKHLMRRGEASPKAPNHFRKGTTQP
Sbjct: 61  CLFQACECHKCVLILERRRVMAAQVALRRQQEAQLKKHLMRRGEASPKAPNHFRKGTTQP 120

Query: 121 QVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGH 180
           QVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGH
Sbjct: 121 QVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGH 180

Query: 181 WLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLS 240
           WLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLS
Sbjct: 181 WLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLS 240

Query: 241 GEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVG 300
           GEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVG
Sbjct: 241 GEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVG 300

Query: 301 LKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAPSVALHIGRL 360
           LKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAPSVALHIGRL
Sbjct: 301 LKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAPSVALHIGRL 360

Query: 361 GSISLLS 367
           GSISLLS
Sbjct: 361 GSISLLS 367


>gi|145046253 DMRT-like family C1B [Homo sapiens]
          Length = 192

 Score =  129 bits (324), Expect = 4e-30
 Identities = 72/128 (56%), Positives = 82/128 (64%), Gaps = 9/128 (7%)

Query: 240 SGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALV 299
           SG+P   P+ P   STLILQPC T DPL LQPQ    S  A  S  SEWQ + EAAEAL+
Sbjct: 74  SGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHSEWQRKLEAAEALL 133

Query: 300 GLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAPSVALHIGR 359
            L++S+QAP         P  ISL  PC PPAPAG +GFQP  P LRP PA S++L IG 
Sbjct: 134 TLRNSAQAP---------PDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISLPIGH 184

Query: 360 LGSISLLS 367
           LG ISLLS
Sbjct: 185 LGCISLLS 192


>gi|116008456 DMRT-like family C1 [Homo sapiens]
          Length = 192

 Score =  129 bits (324), Expect = 4e-30
 Identities = 72/128 (56%), Positives = 82/128 (64%), Gaps = 9/128 (7%)

Query: 240 SGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALV 299
           SG+P   P+ P   STLILQPC T DPL LQPQ    S  A  S  SEWQ + EAAEAL+
Sbjct: 74  SGDPHRAPALPSICSTLILQPCATLDPLLLQPQVPKVSDQALVSAHSEWQRKLEAAEALL 133

Query: 300 GLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAPSVALHIGR 359
            L++S+QAP         P  ISL  PC PPAPAG +GFQP  P LRP PA S++L IG 
Sbjct: 134 TLRNSAQAP---------PDSISLHQPCNPPAPAGDKGFQPPSPSLRPRPASSISLPIGH 184

Query: 360 LGSISLLS 367
           LG ISLLS
Sbjct: 185 LGCISLLS 192


>gi|11056048 doublesex and mab-3 related transcription factor 3
           [Homo sapiens]
          Length = 472

 Score =  103 bits (257), Expect = 2e-22
 Identities = 51/105 (48%), Positives = 63/105 (60%)

Query: 32  PRRAISRSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQ 91
           PR  + R+P CARCRNHGV + LKGHKR C F+ C C KC+LI+ER+RVMAAQVALRRQQ
Sbjct: 19  PRAPLQRTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQ 78

Query: 92  EAQLKKHLMRRGEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTP 136
             +  + L+     +   P         PQ P   +   PQP  P
Sbjct: 79  ANESLESLIPDSLRALPGPPPPGDAVAAPQPPPASQPSQPQPPRP 123


>gi|195947401 doublesex and mab-3 related transcription factor 2
           isoform 1 [Homo sapiens]
          Length = 226

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 50/89 (56%), Positives = 61/89 (68%), Gaps = 6/89 (6%)

Query: 34  RAISRSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQEA 93
           R +SR+P CARCRNHGV + LKGHKR C ++ C+C  C+L++ER+RVMAAQVALRRQQ  
Sbjct: 115 RKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQAT 174

Query: 94  QLKKHLMRRGEASPKAPNHFRKGTTQPQV 122
           + KK L      S K  N  RK   Q QV
Sbjct: 175 EDKKGL------SGKQNNFERKAVYQRQV 197


>gi|5729806 doublesex and mab-3 related transcription factor 2
           isoform 1 [Homo sapiens]
          Length = 226

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 50/89 (56%), Positives = 61/89 (68%), Gaps = 6/89 (6%)

Query: 34  RAISRSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQEA 93
           R +SR+P CARCRNHGV + LKGHKR C ++ C+C  C+L++ER+RVMAAQVALRRQQ  
Sbjct: 115 RKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQAT 174

Query: 94  QLKKHLMRRGEASPKAPNHFRKGTTQPQV 122
           + KK L      S K  N  RK   Q QV
Sbjct: 175 EDKKGL------SGKQNNFERKAVYQRQV 197


>gi|153945850 doublesex and mab-3 related transcription factor 2
           isoform 2 [Homo sapiens]
          Length = 561

 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 50/89 (56%), Positives = 61/89 (68%), Gaps = 6/89 (6%)

Query: 34  RAISRSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQEA 93
           R +SR+P CARCRNHGV + LKGHKR C ++ C+C  C+L++ER+RVMAAQVALRRQQ  
Sbjct: 115 RKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQAT 174

Query: 94  QLKKHLMRRGEASPKAPNHFRKGTTQPQV 122
           + KK L      S K  N  RK   Q QV
Sbjct: 175 EDKKGL------SGKQNNFERKAVYQRQV 197


>gi|170763515 DMRT-like family A1 [Homo sapiens]
          Length = 504

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 39/54 (72%), Positives = 44/54 (81%)

Query: 38  RSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQ 91
           R+P CARCRNHGV + LKGHKR C ++ C C KC LI ER+RVMAAQVALRRQQ
Sbjct: 93  RTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQ 146



 Score = 28.9 bits (63), Expect = 7.6
 Identities = 28/102 (27%), Positives = 35/102 (34%), Gaps = 31/102 (30%)

Query: 121 QVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGH 180
           Q  S    ++ +P    G V+ AP PP      P L             PVP G  V   
Sbjct: 5   QCGSRDRGVSGRPHLAPGLVVAAPPPP-----SPAL-------------PVPSGMQV--- 43

Query: 181 WLPPGFSMPPPVVCRLLYQEPAVS--------LPPFPGFDPG 214
             PP F  PP +  R      A +         PP PG + G
Sbjct: 44  --PPAFLRPPSLFLRAAAAAAAAAAATSGSGGCPPAPGLESG 83


>gi|62241026 doublesex and mab-3 related transcription factor 1
           [Homo sapiens]
          Length = 373

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 38/54 (70%), Positives = 44/54 (81%)

Query: 38  RSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQ 91
           R P CARCRNHG  + LKGHKR C+++ C+C KC LI ER+RVMAAQVALRRQQ
Sbjct: 72  RLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQ 125


>gi|154146231 DMRT-like family A2 [Homo sapiens]
          Length = 542

 Score = 85.5 bits (210), Expect = 7e-17
 Identities = 39/54 (72%), Positives = 44/54 (81%)

Query: 38  RSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQQ 91
           R+P CARCRNHGV + LKGHKR C ++ C C KC LI ER+RVMAAQVALRRQQ
Sbjct: 66  RTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQ 119


>gi|24308352 DMRT-like family B with proline-rich C-terminal, 1
           [Homo sapiens]
          Length = 342

 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 91/318 (28%), Positives = 123/318 (38%), Gaps = 47/318 (14%)

Query: 38  RSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQ-QEAQLK 96
           R+P C+RCRNHG    +KGH   C ++ C C KC LI ER+++MAAQ  L+ Q  E + +
Sbjct: 7   RTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEEEQE 66

Query: 97  KHLMRRGEASPKAPNHFRKGTTQPQVPSGKENIAP-QPQTPHGAVLLAPTPPGKNSCGPL 155
             L  +G   PK  +        P VP    ++ P  P TP G     P P G+      
Sbjct: 67  AALCAQG---PKQASGAAAAAPAP-VPVPAASLRPLSPGTPSGDA--DPGPEGR--AAAC 118

Query: 156 LLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGT 215
               PP           PGP      L     + P    R     P+++ PPF     G+
Sbjct: 119 FFEQPPRGR-------NPGPRALQPVLGGRSHVEPSE--RAAVAMPSLAGPPFGAEAAGS 169

Query: 216 SL--QLPTHGPFTTCPGSHPVLT---APLSGEPQ---GP--PSQPRTHSTLILQPCGTPD 265
                L    P  T PG  P+ T    PL+  P    GP  P     H      P G  D
Sbjct: 170 GYPGPLDLRRPMRTVPG--PLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPF-PLGYLD 226

Query: 266 PLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPP--------- 316
                P   G   ++R    S++Q     +E     + S   P   P +PP         
Sbjct: 227 APPGVPLQQGFRHVSR----SQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQ 282

Query: 317 --NPAWISLLHPCGPPAP 332
              P ++S LH   PP P
Sbjct: 283 FLPPGYLSALHFLPPPPP 300



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 7/98 (7%)

Query: 156 LLSHPP-EASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPG 214
           L+S P  +  P  + P PP P  P   LPP     PP     L+      LPP P   P 
Sbjct: 250 LVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALH-----FLPPPPPPPPP 304

Query: 215 TSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRT 252
           +S  L      T    +       LSGEP  P SQ ++
Sbjct: 305 SSFSLTVLFD-TDKENTDDQDAEVLSGEPSQPSSQEQS 341


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 75/240 (31%), Positives = 86/240 (35%), Gaps = 65/240 (27%)

Query: 115 KGTTQPQ--VPSGKENIAPQPQTPHGAVLLAP-TPPGKNSCGPLLLSHPPEASPLSWTPV 171
           +G  +PQ   P GK    PQ   P G    +P +PPGK   GP     PP+       P 
Sbjct: 124 QGGNRPQGPPPPGK----PQGPPPQGDKSRSPRSPPGKPQ-GP-----PPQGGNQPQGPP 173

Query: 172 PP-----GPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFT 226
           PP     GP   G   P G   PPP         P     P P  D   S Q P   P  
Sbjct: 174 PPPGKPQGPPPQGGKKPQG---PPP---------PGKPQGPPPQGDKSRSSQSPPGKPQG 221

Query: 227 TCP--GSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQ-PQASGASCLARTS 283
             P  G+ P    P  G+PQGPP Q         +P G P P + Q P A G S      
Sbjct: 222 PPPQGGNQPQGPPPPPGKPQGPPPQGGN------KPQGPPPPGKPQGPPAQGGS------ 269

Query: 284 GPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGP 343
                                SQ+ R  P  P  P      +P GPP PAGG   QP  P
Sbjct: 270 --------------------KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP 309



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 60/229 (26%), Positives = 73/229 (31%), Gaps = 28/229 (12%)

Query: 124 SGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGHWLP 183
           S  +N+           L+A  P G +  G      PP        P P G   P    P
Sbjct: 14  SSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPP 73

Query: 184 PGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEP 243
           PG    PP         P       P   PG     P  G      G+ P    P  G+P
Sbjct: 74  PGKPQGPP---------PQGDKSRSPRSPPGKPQGPPPQG------GNQPQGPPPPPGKP 118

Query: 244 QGPPSQPRTHSTLILQPCGTPDPLQLQ-PQASGASCLARTSGPSEWQLQQEAAEALVGLK 302
           QGPP Q         +P G P P + Q P   G    +  S P + Q             
Sbjct: 119 QGPPPQGGN------RPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG------ 166

Query: 303 DSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAP 351
           +  Q P   P  P  P       P GPP P   +G  P G   R S +P
Sbjct: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP 215



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 8/133 (6%)

Query: 119 QPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVP 178
           +PQ P  + + +   Q+P G     P   G    GP     PP   P    P P G   P
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGP----PPPPGKPQG--PPPQGGNKP 251

Query: 179 GHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAP 238
               PPG    PP       Q  A S P  P   P      P  GP     G+     AP
Sbjct: 252 QGPPPPGKPQGPPAQGGSKSQS-ARSPPGKPQGPPQQEGNNP-QGPPPPAGGNPQQPQAP 309

Query: 239 LSGEPQGPPSQPR 251
            +G+PQGPP  P+
Sbjct: 310 PAGQPQGPPRPPQ 322


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 68/244 (27%), Positives = 91/244 (37%), Gaps = 24/244 (9%)

Query: 103 GEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCG--PLLLSHP 160
           G + PK  +   + T+ P +PS ++N +    +    +L A  P  +   G  P   S P
Sbjct: 143 GSSDPKDIDQDNRSTS-PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 201

Query: 161 PEASPLSWT-PVPPGPWVPGHWLPPGFSMP-------PPVVCRLLYQEPAV--SLPPFPG 210
           P    L    P P    VP    P     P        PV    + Q PA+    PP P 
Sbjct: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261

Query: 211 FDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEP----QGPPSQPRTHSTLILQPCGTPDP 266
             P  S     H P     GS    +AP   +P    QGPP      +  +LQ  G P P
Sbjct: 262 PPPHPS----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 317

Query: 267 LQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHP 326
             L PQAS       TS  + +        A      S Q PR  P +PP P  +++ H 
Sbjct: 318 FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP-LPPAP--LAMPHI 374

Query: 327 CGPP 330
             PP
Sbjct: 375 KPPP 378



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 62/258 (24%), Positives = 87/258 (33%), Gaps = 64/258 (24%)

Query: 82  AAQVALRRQQEAQLKKHLMRRGEASPKAP---NHFRKGTTQP--QVPSGKENIAP---QP 133
           A+Q AL+ QQ          R +  P AP    H +   T P  Q+P+ + +  P     
Sbjct: 348 ASQSALQSQQPP--------REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 399

Query: 134 QTPHGAVLLAPTPPGKNSCGPLLLSHPPEA-----------SPLSWTPVPPGPWVPGHWL 182
            +P       P PP       L   HPP A            PL  +P  P        L
Sbjct: 400 PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL 459

Query: 183 PPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGE 242
           PP  +  PP     +  +P  +  PF                    PG  P +T P    
Sbjct: 460 PPPPASHPPTGLHQVAPQPPFAQHPF-------------------VPGGPPPITPPTCPS 500

Query: 243 PQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGP-SEWQLQQEAAEALVGL 301
              PP+ P T +     PC           ASG S    +S P    Q+++EA       
Sbjct: 501 TSTPPAGPGTSAQ---PPCS-------GAAASGGSIAGGSSCPLPTVQIKEEAL------ 544

Query: 302 KDSSQAPRVTPSVPPNPA 319
            D ++ P   P  P +P+
Sbjct: 545 -DDAEEPESPPPPPRSPS 561


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 68/244 (27%), Positives = 91/244 (37%), Gaps = 24/244 (9%)

Query: 103 GEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCG--PLLLSHP 160
           G + PK  +   + T+ P +PS ++N +    +    +L A  P  +   G  P   S P
Sbjct: 697 GSSDPKDIDQDNRSTS-PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 161 PEASPLSWT-PVPPGPWVPGHWLPPGFSMP-------PPVVCRLLYQEPAV--SLPPFPG 210
           P    L    P P    VP    P     P        PV    + Q PA+    PP P 
Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815

Query: 211 FDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEP----QGPPSQPRTHSTLILQPCGTPDP 266
             P  S     H P     GS    +AP   +P    QGPP      +  +LQ  G P P
Sbjct: 816 PPPHPS----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 871

Query: 267 LQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHP 326
             L PQAS       TS  + +        A      S Q PR  P +PP P  +++ H 
Sbjct: 872 FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP-LPPAP--LAMPHI 928

Query: 327 CGPP 330
             PP
Sbjct: 929 KPPP 932



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 62/258 (24%), Positives = 87/258 (33%), Gaps = 64/258 (24%)

Query: 82   AAQVALRRQQEAQLKKHLMRRGEASPKAP---NHFRKGTTQP--QVPSGKENIAP---QP 133
            A+Q AL+ QQ          R +  P AP    H +   T P  Q+P+ + +  P     
Sbjct: 902  ASQSALQSQQPP--------REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 953

Query: 134  QTPHGAVLLAPTPPGKNSCGPLLLSHPPEA-----------SPLSWTPVPPGPWVPGHWL 182
             +P       P PP       L   HPP A            PL  +P  P        L
Sbjct: 954  PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL 1013

Query: 183  PPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGE 242
            PP  +  PP     +  +P  +  PF                    PG  P +T P    
Sbjct: 1014 PPPPASHPPTGLHQVAPQPPFAQHPF-------------------VPGGPPPITPPTCPS 1054

Query: 243  PQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGP-SEWQLQQEAAEALVGL 301
               PP+ P T +     PC           ASG S    +S P    Q+++EA       
Sbjct: 1055 TSTPPAGPGTSAQ---PPCS-------GAAASGGSIAGGSSCPLPTVQIKEEAL------ 1098

Query: 302  KDSSQAPRVTPSVPPNPA 319
             D ++ P   P  P +P+
Sbjct: 1099 -DDAEEPESPPPPPRSPS 1115


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 68/244 (27%), Positives = 91/244 (37%), Gaps = 24/244 (9%)

Query: 103 GEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCG--PLLLSHP 160
           G + PK  +   + T+ P +PS ++N +    +    +L A  P  +   G  P   S P
Sbjct: 697 GSSDPKDIDQDNRSTS-PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 755

Query: 161 PEASPLSWT-PVPPGPWVPGHWLPPGFSMP-------PPVVCRLLYQEPAV--SLPPFPG 210
           P    L    P P    VP    P     P        PV    + Q PA+    PP P 
Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815

Query: 211 FDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEP----QGPPSQPRTHSTLILQPCGTPDP 266
             P  S     H P     GS    +AP   +P    QGPP      +  +LQ  G P P
Sbjct: 816 PPPHPS----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQP 871

Query: 267 LQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHP 326
             L PQAS       TS  + +        A      S Q PR  P +PP P  +++ H 
Sbjct: 872 FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP-LPPAP--LAMPHI 928

Query: 327 CGPP 330
             PP
Sbjct: 929 KPPP 932



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 62/258 (24%), Positives = 87/258 (33%), Gaps = 64/258 (24%)

Query: 82   AAQVALRRQQEAQLKKHLMRRGEASPKAP---NHFRKGTTQP--QVPSGKENIAP---QP 133
            A+Q AL+ QQ          R +  P AP    H +   T P  Q+P+ + +  P     
Sbjct: 902  ASQSALQSQQPP--------REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSG 953

Query: 134  QTPHGAVLLAPTPPGKNSCGPLLLSHPPEA-----------SPLSWTPVPPGPWVPGHWL 182
             +P       P PP       L   HPP A            PL  +P  P        L
Sbjct: 954  PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNL 1013

Query: 183  PPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGE 242
            PP  +  PP     +  +P  +  PF                    PG  P +T P    
Sbjct: 1014 PPPPASHPPTGLHQVAPQPPFAQHPF-------------------VPGGPPPITPPTCPS 1054

Query: 243  PQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGP-SEWQLQQEAAEALVGL 301
               PP+ P T +     PC           ASG S    +S P    Q+++EA       
Sbjct: 1055 TSTPPAGPGTSAQ---PPCS-------GAAASGGSIAGGSSCPLPTVQIKEEAL------ 1098

Query: 302  KDSSQAPRVTPSVPPNPA 319
             D ++ P   P  P +P+
Sbjct: 1099 -DDAEEPESPPPPPRSPS 1115


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 72/268 (26%), Positives = 93/268 (34%), Gaps = 44/268 (16%)

Query: 106 SPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLS------- 158
           SP+APN       Q             P +P  +  ++P+    +   P L +       
Sbjct: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483

Query: 159 HPPEASPLSWTPVPPGPWVPGHWLPP-GFSMPPPVVCRLLYQEPAVSLPPFPGFDPGT-- 215
            PP + P+S +  PP    P    PP   + PPP     L   P  +LP  P   PG   
Sbjct: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543

Query: 216 ---SLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHS------------------ 254
              S  LP     T  P + PVL APL   P  PP+ P   +                  
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603

Query: 255 TLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPR-VTPS 313
           TL L P G P P    P  S +S L   SGP        A      L+     P     +
Sbjct: 604 TLALAP-GPPPP----PSRSPSSTL---SGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655

Query: 314 VPPNPAWISLLHPC----GPPAPAGGRG 337
            PP  A ++  HP     GP  P   RG
Sbjct: 656 SPPPDAELAACHPAAWSRGPAPPLAFRG 683



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 68/273 (24%), Positives = 89/273 (32%), Gaps = 31/273 (11%)

Query: 106 SPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASP 165
           SP AP   +   + P  P  +   +    T        P+PP      P     PP+A P
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP-----PPQAPP 398

Query: 166 LSWTP---VPPGPWVPGHWLPPGFSMP--PPVVCRLLYQEPAVSLPPFPGFDPGTSLQLP 220
               P    PP P       P     P  P  +   L Q P    P  P   P +    P
Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458

Query: 221 THGPFTTCPG-SHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCL 279
              P  T P  + P L AP    P  PP+ P       + P  TP P    P A+    L
Sbjct: 459 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPP------MSPSATPPPQAPPPLAAPPLQL 512

Query: 280 ARTSGPSEWQLQQEAAEAL----------VGLKDSSQAPRVTPSVPPNPAWISLLHPC-- 327
           A+    +   L     +AL               S+  P    + PP  A   L  P   
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572

Query: 328 GPPAPAGGRGFQPVGPCLRPSPAPSVALHIGRL 360
            PP+P      Q   P   P+P P  ++   RL
Sbjct: 573 VPPSPPASPTLQ--APRRPPTPGPDTSVSGPRL 603


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 72/268 (26%), Positives = 93/268 (34%), Gaps = 44/268 (16%)

Query: 106 SPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLS------- 158
           SP+APN       Q             P +P  +  ++P+    +   P L +       
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 444

Query: 159 HPPEASPLSWTPVPPGPWVPGHWLPP-GFSMPPPVVCRLLYQEPAVSLPPFPGFDPGT-- 215
            PP + P+S +  PP    P    PP   + PPP     L   P  +LP  P   PG   
Sbjct: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504

Query: 216 ---SLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHS------------------ 254
              S  LP     T  P + PVL APL   P  PP+ P   +                  
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 564

Query: 255 TLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPR-VTPS 313
           TL L P G P P    P  S +S L   SGP        A      L+     P     +
Sbjct: 565 TLALAP-GPPPP----PSRSPSSTL---SGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 616

Query: 314 VPPNPAWISLLHPC----GPPAPAGGRG 337
            PP  A ++  HP     GP  P   RG
Sbjct: 617 SPPPDAELAACHPAAWSRGPAPPLAFRG 644



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 68/273 (24%), Positives = 89/273 (32%), Gaps = 31/273 (11%)

Query: 106 SPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASP 165
           SP AP   +   + P  P  +   +    T        P+PP      P     PP+A P
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP-----PPQAPP 359

Query: 166 LSWTP---VPPGPWVPGHWLPPGFSMP--PPVVCRLLYQEPAVSLPPFPGFDPGTSLQLP 220
               P    PP P       P     P  P  +   L Q P    P  P   P +    P
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419

Query: 221 THGPFTTCPG-SHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCL 279
              P  T P  + P L AP    P  PP+ P       + P  TP P    P A+    L
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPP------MSPSATPPPQAPPPLAAPPLQL 473

Query: 280 ARTSGPSEWQLQQEAAEAL----------VGLKDSSQAPRVTPSVPPNPAWISLLHPC-- 327
           A+    +   L     +AL               S+  P    + PP  A   L  P   
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533

Query: 328 GPPAPAGGRGFQPVGPCLRPSPAPSVALHIGRL 360
            PP+P      Q   P   P+P P  ++   RL
Sbjct: 534 VPPSPPASPTLQ--APRRPPTPGPDTSVSGPRL 564


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 68/261 (26%), Positives = 92/261 (35%), Gaps = 29/261 (11%)

Query: 95  LKKHLMRRGEASPKAPN---HFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNS 151
           L  HL++   + P +P     F    + P  PS        P      + + P+PP    
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715

Query: 152 CGPLLLSHPPEASPLSWTP--VPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFP 209
             P     P    PL+  P  VPP P       P   + PPP V  LL   P + +PP P
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS--ATPPPRVPPLL-AAPPLQVPPSP 772

Query: 210 GFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQP-----RTHSTLILQPCGTP 264
              P +    P   P    P +  + T PL   P  P S P        ++L + P  TP
Sbjct: 773 ---PASLPMSPLAKPPPQAPPA--LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827

Query: 265 DPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLL 324
            P Q  P  +        S P+   LQ        G   S   PR+T ++ P P      
Sbjct: 828 PP-QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP------ 880

Query: 325 HPCGPPAPAGGRGFQPVGPCL 345
               PP P+        GP L
Sbjct: 881 ----PPPPSRSPSSTLSGPDL 897



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 61/228 (26%), Positives = 79/228 (34%), Gaps = 17/228 (7%)

Query: 131 PQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPP 190
           P P+TP       P  P   +  PL     P  SPL+ TP P  P  P   LPP  + P 
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA-TPPPQAP--PXLALPPLQAPPS 635

Query: 191 PVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTH---GPFTTCPGSHPVLTAPLSGEPQGPP 247
           P          +  L P     P     L  H    PF+  P   P + AP S  P  PP
Sbjct: 636 PPA--------SPPLSPLATPSPQAPNALAVHLLQAPFSPPPS--PPVQAPFS-PPASPP 684

Query: 248 SQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQA 307
             P         P     PLQ+ P    +  ++ ++ P        AA  L        +
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744

Query: 308 PRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAPSVAL 355
           P ++PS  P P    LL       P       P+ P  +P P    AL
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 64/232 (27%), Positives = 79/232 (34%), Gaps = 33/232 (14%)

Query: 123 PSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGHWL 182
           PSG +     P       L A  PP      PL L+ P  ++P S   +P  P  P    
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 368

Query: 183 PPGFSMP-----------PPVVCRLLYQEPAVSLPPFP----GFDPGTSLQLP----THG 223
           PP  + P           PP+        P++  PP P         TSL  P    TH 
Sbjct: 369 PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHS 428

Query: 224 PFTTCP-GSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLART 282
             T  P  +   LT+P S     PP  P   + L L P   P    L P  S        
Sbjct: 429 FLTMSPRQTQASLTSP-SRPASTPPDSPPLQAPLSL-PASPPLQTSLSPAVS-------- 478

Query: 283 SGPSEWQLQQEAAEALVGL-KDSSQAPRVTPSVPPNPAWISLLHPCGPPAPA 333
             P    L     +AL  L   S QAP  +  +PP     SL  P     PA
Sbjct: 479 --PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA 528



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 67/258 (25%), Positives = 93/258 (36%), Gaps = 39/258 (15%)

Query: 109 APNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSW 168
           +P   +   T P  P+     +P  Q P   + L  +PP + S  P +    P +SPL+ 
Sbjct: 433 SPRQTQASLTSPSRPASTPPDSPPLQAP---LSLPASPPLQTSLSPAV---SPLSSPLTI 486

Query: 169 TPVPPGPWVPGH--WLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFT 226
            P+     +  H    P    + PP+  +     P++  PP        SL  P   P  
Sbjct: 487 HPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPP-------ASLTTP---PLE 536

Query: 227 TCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQ---ASGASCLARTS 283
             P   P         P    S P T   L   PC  P PLQ  P           +  +
Sbjct: 537 NLPSLAP--------PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIA 588

Query: 284 GPSEWQLQQEAAEALVGLKDSSQAPRVT--PSVPPNPAWISLLHPCGPPAPAGGRGFQPV 341
            P        A+  L GL     +P  T  P  PP  A   L  P  PPA        P+
Sbjct: 589 TPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPAS------PPL 642

Query: 342 GPCLRPSP-AP-SVALHI 357
            P   PSP AP ++A+H+
Sbjct: 643 SPLATPSPQAPNALAVHL 660


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 60/225 (26%), Positives = 73/225 (32%), Gaps = 37/225 (16%)

Query: 144 PTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPV----------- 192
           P P      G   + H P   P  W   PP P   G   PPG   PPP+           
Sbjct: 400 PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH-PPGHHGPPPMDQYLGSTPVGS 458

Query: 193 -VCRL-----LYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGP 246
            V RL     +   P + + P P   P      P  GP             P   + Q P
Sbjct: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL-----------PPWQQQQQQP 507

Query: 247 PSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQ 306
           P  P   S++      +  PL  Q   +  +  A T     WQ QQ AA A  G      
Sbjct: 508 PPPPPPSSSM-----ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQG 562

Query: 307 APRVTPSVPP--NPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSP 349
            P + P +PP   P       P  PP P G  G     P   P P
Sbjct: 563 NPTMVP-LPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPP 606


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 62/203 (30%), Positives = 81/203 (39%), Gaps = 42/203 (20%)

Query: 109  APNHFRKGTTQPQVPSG--KENIAPQPQT---PHGAVLLAPTPPGKNSCGPLLLSHP--- 160
            A +HF  G     +P+G     I PQPQ    PH +    P PP +    PL L HP   
Sbjct: 934  AQHHFSSG-----IPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQ----PLPLQHPHLF 984

Query: 161  PEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVS-LP------PFPGFDP 213
            P  +P    P  P P+ P    P     PPP +   LY  PA   LP      PFP   P
Sbjct: 985  PPQAPGLLPPQSPYPYAPQ---PGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGP 1041

Query: 214  GTSLQLPTHGP--FTTCPGSHPV--LTAPLS--GEPQGPPSQPRTHSTLILQPCGTPDPL 267
                  P H P  +   P + P+    APL+  G      S P  H  L+  P  +P P 
Sbjct: 1042 ----PQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPH--LVPSPAPSPGPG 1095

Query: 268  QLQPQASGAS---CLARTSGPSE 287
             + P+   A    CL R +  ++
Sbjct: 1096 PVPPRPPAAEPPPCLRRGAAAAD 1118



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 75/245 (30%), Positives = 87/245 (35%), Gaps = 38/245 (15%)

Query: 130  APQPQT--PHGAVLLAPTPPGKNSCGPLLLSHP-PEASPLSWTPVPPGPWVPGHWLPPGF 186
            AP PQ   P  A+ + P     +S    + SH  P  +P   TP PP         PP F
Sbjct: 863  APPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNP---TPAPP---------PPCF 910

Query: 187  SMPPPVVCRLLYQEPAVSLPPFPG---FDPG--TSLQLPTHGPFTTCPGSHPVLTAPLSG 241
             +PPP      Y  PA +  P P    F  G       P  GP    P  HP      + 
Sbjct: 911  PVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGP---QPQPHPQPHPSQAF 967

Query: 242  EPQGPPSQPRTHSTLILQPCGTPDPLQLQ---PQASGASCLARTSGPSEWQLQQ-EAAEA 297
             PQ PP QP       L P   P  L  Q   P A     L +   P   QL    A + 
Sbjct: 968  GPQ-PPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDP 1026

Query: 298  LVGLKDSSQAPRVTPSVPPNPAW----ISLLHPCGP-PAPAGGRGFQPVG-----PCLRP 347
            L     +   P   P  PP+P           P GP  AP   RG    G     P L P
Sbjct: 1027 LPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVP 1086

Query: 348  SPAPS 352
            SPAPS
Sbjct: 1087 SPAPS 1091


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 57/197 (28%), Positives = 77/197 (39%), Gaps = 36/197 (18%)

Query: 105 ASPKAPNHFRKGTTQPQVPSGKEN---------IAPQPQTPHGAVLLA---PTPPGKNSC 152
           ASP++    R  + +P+ PS  E+         ++P+P+ P  AV      P PPG    
Sbjct: 263 ASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGS--- 319

Query: 153 GPLLLSHPPEASPLSWTP------VPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLP 206
            P      P AS   W P      V PGPW P   + PG   P P V    ++  +VS  
Sbjct: 320 -PRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVS-- 376

Query: 207 PFPGFDPGTSLQLPTHGP------FTTCPGSHPVLTAPLSGE--PQGPPSQPRTHSTL-- 256
           P     P  S +    GP        T    H     P+S E    GPP  P   S    
Sbjct: 377 PSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGS 436

Query: 257 --ILQPCGTPDPLQLQP 271
             + +P G+PD  +L P
Sbjct: 437 PELRKPSGSPDLWKLSP 453



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 70/273 (25%), Positives = 92/273 (33%), Gaps = 38/273 (13%)

Query: 105 ASPKAPNHFRKGTTQPQVP-SGKENIAPQPQTPHGAVLLAPTP-PGKNSCGPLLLSHPPE 162
           +SP+ P       +Q   P    E   P P +P         P P K S  P  L  P  
Sbjct: 183 SSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSA 242

Query: 163 ASPLSWTPV---PPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLP--------PFPGF 211
           +SP S  PV    P PW P     P  S       R    EP    P        PFP  
Sbjct: 243 SSPES--PVLAASPEPWGPS----PAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAV 296

Query: 212 DPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGP--PSQPRTHSTLILQ------PCGT 263
            P      P   P +  PG  P    P    P     P +P   +  +        P  +
Sbjct: 297 SPEPRRPAPAVSPGSWKPGP-PGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVS 355

Query: 264 PDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPP-NPAWIS 322
           P P +  P  S AS  + +  PS W+    + E+       S  P +  + P  +P    
Sbjct: 356 PGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESW-----KSGPPELRKTAPTLSPEHWK 410

Query: 323 LLHPCGPPAPAGGRGFQPVGPCLRPSPAPSVAL 355
            + P  P     G    P+ P +R SPA S  L
Sbjct: 411 AVPPVSPELRKPG---PPLSPEIR-SPAGSPEL 439


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 70/256 (27%), Positives = 84/256 (32%), Gaps = 44/256 (17%)

Query: 107 PKAPNHFRKGTTQPQVPSGKE-NIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASP 165
           P+  N  R   + P  P G       QPQ P       P PPGK    P    + P+  P
Sbjct: 164 PQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP-------PPPPGKPQGPPPQGGNKPQGPP 216

Query: 166 LSWTPVPPGPWVPGHWL----PPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPT 221
               P  P P           PPG    PP       Q P    PP PG   G   Q   
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPPQ--- 269

Query: 222 HGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPD--------------PL 267
                   G +     P  G+PQGPP Q  + S     P G P               P 
Sbjct: 270 --------GGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 321

Query: 268 QLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPC 327
             +PQ        +  GP     + +      G K  S++ R  P  P  P      +P 
Sbjct: 322 PGKPQGPPPQGGNKPQGPPP-PGKPQGPPPQGGSK--SRSARSPPGKPQGPPQQEGNNPQ 378

Query: 328 GPPAPAGGRGFQPVGP 343
           GPP PAGG   QP  P
Sbjct: 379 GPPPPAGGNPQQPQAP 394



 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 73/247 (29%), Positives = 84/247 (34%), Gaps = 38/247 (15%)

Query: 115 KGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEA----SPLSWTP 170
           +G  QPQ P         P    G     P PPGK   GP     PP+     SP S   
Sbjct: 63  QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ-GP-----PPQGDKSRSPRSPPG 116

Query: 171 VPPGP------WVPGHWLPPGFSMPPPVVCRLLYQEP----AVSLPPFPGFDPGTSLQLP 220
            P GP         G   PPG    PP       Q P        PP  G +   S + P
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176

Query: 221 THGPFTTCP--GSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQ---PQASG 275
              P    P  G+ P    P  G+PQGPP Q         +P G P P + Q   PQ   
Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN------KPQGPPPPGKPQGPPPQGDN 230

Query: 276 ASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGG 335
            S  AR S P + Q             +  Q P   P  P  P       P GPP P   
Sbjct: 231 KSQSAR-SPPGKPQGPPPQG------GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 283

Query: 336 RGFQPVG 342
           +G  P G
Sbjct: 284 QGPPPQG 290



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 65/236 (27%), Positives = 75/236 (31%), Gaps = 41/236 (17%)

Query: 120 PQVPSGKENIAP-----QPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASP---LSWTPV 171
           P  P GK    P     QPQ P       P PPGK    P    + P+  P       P 
Sbjct: 50  PPSPPGKPQGPPPQGGNQPQGP-------PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 102

Query: 172 PPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGS 231
           P G        PPG    PP       Q P    PP PG   G   Q           G 
Sbjct: 103 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPPQ-----------GG 147

Query: 232 HPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQ 291
           +     P  G+PQGPP Q    S     P G P      P   G +   +  GP     +
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ----GPPPQGGN---QPQGPPPPPGK 200

Query: 292 QEAAEALVGLKDSSQAPRVTPSVPP----NPAWISLLHPCGPPAPAGGRGFQPVGP 343
            +      G K     P   P  PP    N +  +   P  P  P    G QP GP
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP 256



 Score = 37.0 bits (84), Expect = 0.028
 Identities = 45/146 (30%), Positives = 53/146 (36%), Gaps = 27/146 (18%)

Query: 107 PKAPNHFRKGTTQPQVPSGKE-NIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASP 165
           P+  +  R   + P  P G       QPQ P       P PPGK   GP     PP+   
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP-------PPPPGKPQ-GP-----PPQGGN 334

Query: 166 LSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPF 225
               P PPG        P G   PPP          A S P  P   P      P  GP 
Sbjct: 335 KPQGPPPPGK-------PQG---PPPQGGSK--SRSARSPPGKPQGPPQQEGNNP-QGPP 381

Query: 226 TTCPGSHPVLTAPLSGEPQGPPSQPR 251
               G+     AP +G+PQGPP  P+
Sbjct: 382 PPAGGNPQQPQAPPAGQPQGPPRPPQ 407


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 63/257 (24%), Positives = 88/257 (34%), Gaps = 34/257 (13%)

Query: 106  SPKAPNHFRKGTTQPQVPSGKENIA-PQPQTPHGAVLLAP-------TPPGKNSCGPLLL 157
            SP  P+     T     P   + +  P  +TP  +V+  P       TP  K +    + 
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914

Query: 158  SHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL 217
            S  P+ +    TP P G  +P    P G   PP          PA   P +    P  + 
Sbjct: 915  SSSPKKARA--TPAPKG--IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP 970

Query: 218  QLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGAS 277
              P  GP T  P   P   A     P+G P+ P         P G P P  + P +   S
Sbjct: 971  PSPKGGPATPSPKGAPTPPAATPPSPKGGPATP--------SPKGAPTPPAVTPPSPKGS 1022

Query: 278  CLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRG 337
              A T  P        A         +  +P+ +P+  P P           P+P GG  
Sbjct: 1023 -PAATPFPKGASTPPAA---------TPPSPKGSPAATPLPKGAPTTPAATLPSPKGG-- 1070

Query: 338  FQPVGPCLRPSPAPSVA 354
              P  P L+ +P P  A
Sbjct: 1071 --PATPSLKGAPTPPAA 1085



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 58/234 (24%), Positives = 76/234 (32%), Gaps = 23/234 (9%)

Query: 120  PQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHP-PEASPLSWTPVPPGPWVP 178
            P  PS K    P   TP        TP  K +  P  ++ P P+ SP + TP P G   P
Sbjct: 977  PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA-TPFPKGASTP 1035

Query: 179  GHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAP 238
                PP     P           A  LP      P  +L  P  GP T      P   A 
Sbjct: 1036 PAATPPSPKGSPA----------ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085

Query: 239  LSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQA--SGASCLARTSGPSEWQLQQEAAE 296
                P+G P+ P         P G P P    P +   G +       P+       + +
Sbjct: 1086 TPPSPKGGPATP--------SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPK 1137

Query: 297  ALVGLKDSSQAPRVTPSVPPNP-AWISLLHPCGPPAPAGGRGFQPVGPCLRPSP 349
              +       AP    + PP+P   ++   P G P         P G    PSP
Sbjct: 1138 GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSP 1191



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 57/227 (25%), Positives = 75/227 (33%), Gaps = 30/227 (13%)

Query: 105  ASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEAS 164
            A+P +P   + G   P         A  P +P G  L  P+P G  +  P      P+  
Sbjct: 1200 ATPPSP---KGGLATPSPKGAPTTPAATPPSPKGG-LATPSPKGAPTT-PAATPPSPKGG 1254

Query: 165  PLSWTPVPPGPWVPGHWLPP----GFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQL- 219
            P   TP P G   P    PP    G + PP          PAV  PP P   P TS    
Sbjct: 1255 PA--TPPPKGAPTPPAATPPSLKGGLATPPHKGA----PNPAVVTPPSPKGGPATSPPKG 1308

Query: 220  -----------PTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQ 268
                       P   P T  P   P   A     P+G P+ P T  +      G   P  
Sbjct: 1309 APTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS---SKGGPTTPSS 1365

Query: 269  LQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVP 315
             +     A+  +   GP+      +   A+   K    +P V P  P
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 69/287 (24%), Positives = 93/287 (32%), Gaps = 45/287 (15%)

Query: 104  EASPKAPNHFRKGTTQPQVPSGKENIAPQPQTP--HGAVLLAPTPPGKNSCGPLLLSHP- 160
            + +P  P         P  PS KE   P   TP   G   + P  P +    P     P 
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403

Query: 161  -PEASPLSWTPVPPGPWV-PGHWLPPGFSMPPPVVCRL-LYQEPAVS------------- 204
             P   PLS    P  P    G   P    + PP V  + L + PA S             
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463

Query: 205  -------LPPFPGFDPG----TSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTH 253
                    PP P   P      +   P   P T  P   P L A +   P+  P+ P + 
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523

Query: 254  STLILQPCGT----PDPLQLQPQASGASCLARTSGPSEWQL--QQEAAEALVGLKDSSQA 307
               I  P  T      P  L P+ +          P +       + A A    K++S  
Sbjct: 1524 RDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582

Query: 308  PRVTPSV---PPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAP 351
            P VTPS     P+P  + +      P+P       P  P + P P+P
Sbjct: 1583 PAVTPSTYKGAPSPKELLIPPAVTSPSPKEA----PTPPAVTP-PSP 1624



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 64/260 (24%), Positives = 89/260 (34%), Gaps = 37/260 (14%)

Query: 105  ASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLL-----APTPPGKNSCGPL--LL 157
            A+P +P   + G   P         A  P +P G +       APT P      P   L 
Sbjct: 1085 ATPPSP---KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141

Query: 158  SHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL 217
            + PP+ +P +    PP P         G + PPP        + A + P      P   L
Sbjct: 1142 TPPPKGAPTTPAATPPSP-------KGGLATPPP--------KGAPTTPAATPPSPKGGL 1186

Query: 218  QLPTHGPFTTCPGSHPVLTAPLSG----EPQGPPSQPRTHSTLILQPCGTPDP--LQLQP 271
              P+     T P + P   +P  G     P+G P+ P            TP P      P
Sbjct: 1187 ATPSPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1244

Query: 272  QASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPA 331
             A+  S     + P         A     LK     P    +  PNPA ++   P G PA
Sbjct: 1245 AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA--PNPAVVTPPSPKGGPA 1302

Query: 332  PAGGRGFQPVGPCLRPSPAP 351
             +  +G  P  P   P P+P
Sbjct: 1303 TSPPKG-APTPPAATP-PSP 1320



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 68/302 (22%), Positives = 93/302 (30%), Gaps = 70/302 (23%)

Query: 117 TTQPQVPSGKEN--IAPQPQT---PHGAVLLAP---------------TPPGKNSCGPLL 156
           TT P VP+  EN  +AP PQ    P   ++LAP               TPPG      + 
Sbjct: 696 TTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGI- 754

Query: 157 LSHPPEASPLSWTP----------------------VPPGPWVPGHWLPPGFSMPPPVVC 194
            SH    +P++ +P                      +   P   G  + P    PP    
Sbjct: 755 -SHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG 813

Query: 195 RLLYQEPAVSL-----PPFPGFDPGTSLQLP--------THGPFTTCPGSHPVLTAPLSG 241
                 P  +L     P    F P  SL           TH P    P   P  +A    
Sbjct: 814 SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL 873

Query: 242 EPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGL 301
            P+G    P+   T  +     P      P    A  L+ TS   +      A + +   
Sbjct: 874 SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933

Query: 302 KDSSQAPRVTPSVP---------PNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPAPS 352
                AP    + P         P+P W        PP+P GG    P  P  + +P P 
Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG----PATPSPKGAPTPP 989

Query: 353 VA 354
            A
Sbjct: 990 AA 991



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 63/263 (23%), Positives = 91/263 (34%), Gaps = 48/263 (18%)

Query: 118 TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWV 177
           T P+ P+   N+   P +P    L +P         P L   P  ++PL+   + P    
Sbjct: 95  TAPEAPTFLPNLIGPPISPAALALASPM------IAPTLKGTPSSSAPLALVALAPHSVQ 148

Query: 178 PGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTA 237
                PP     PP V             P    +P T+L      P    P        
Sbjct: 149 KSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKV---PSEVVPN------- 198

Query: 238 PLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEA 297
                P+G PS P   ST+    C TP    +    SG + L +T+  +        A A
Sbjct: 199 -----PKGTPSPPCIVSTVPYH-CVTP----MASIQSGVASLPQTTPTTT------LAIA 242

Query: 298 LVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPA---------PAGGRGFQPVGPCLRPS 348
              +KD++ +  +    P NP  +SL  P  PPA         P      +  GP   P 
Sbjct: 243 SPQVKDTTISSVLIS--PQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300

Query: 349 PAPSVALHIGRL-----GSISLL 366
              S+  H+  L     GS+ LL
Sbjct: 301 FPISLGSHLAPLHQSSFGSVQLL 323



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 56/257 (21%), Positives = 76/257 (29%), Gaps = 23/257 (8%)

Query: 100  MRRGEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSH 159
            ++ G A+P            P  P G    +P    P       P+P G         + 
Sbjct: 1274 LKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG------TP 1327

Query: 160  PPEASPLSWTPVPPG----PWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGT 215
            PP+ +P      PP     P +P     P     P          P  + P   G  P  
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPA--TTPSSKGGPTTPSSKEGPTPPAATPSHKG-GPAM 1384

Query: 216  SLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASG 275
            +   P  GP    P   P   A +   P+  P+ P T      +   TP    L P A  
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR-----EGAATPSKGDLTPPAVT 1439

Query: 276  ASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGG 335
               L +    S      +   A    K     P VTP  P  P     +     P  A  
Sbjct: 1440 PVSLKKAPATS----APKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495

Query: 336  RGFQPVGPCLRPSPAPS 352
                P+G    P+  PS
Sbjct: 1496 TP-APMGAPTLPAVIPS 1511



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 61/244 (25%), Positives = 81/244 (33%), Gaps = 35/244 (14%)

Query: 107  PKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPL 166
            P  P+  +   T P   + K   A  PQ   G     P   G  +   +L++  PE++P+
Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMG-ATVPQASKGL----PAKKGPTALKEVLVAPAPESTPI 1695

Query: 167  SWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFT 226
               P   GP           S   P +C            P P    G+   L T  P  
Sbjct: 1696 ITAPTRKGPQTKKS------SATSPPIC------------PDPSAKNGSKGPLSTVAPAP 1737

Query: 227  TCP----GSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLART 282
              P     S        S  P+GP + P + ++  L        L   P+   AS  A  
Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL---PKPESASVSAAP 1794

Query: 283  SGPSEWQLQQEAAEALVG----LKDSSQAPRVTPSVPPNPAWISLLHPCGPPAP-AGGRG 337
            S P    L       L      L  S      +PS P  PA    L P  PP P +GG  
Sbjct: 1795 SPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVP 1854

Query: 338  FQPV 341
            FQ V
Sbjct: 1855 FQSV 1858



 Score = 32.3 bits (72), Expect = 0.69
 Identities = 63/277 (22%), Positives = 91/277 (32%), Gaps = 46/277 (16%)

Query: 104 EASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEA 163
           +A+PK    F+  ++ P++P   E    +        L  P P GK +           +
Sbjct: 564 QAAPKNSPSFQSTSSSPEIPLSPEATLAKKS------LGEPLPIGKPASSMTSPLGVNSS 617

Query: 164 SPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHG 223
           + +  T    GP   G  L      P      L   +PA   P       GTS    T  
Sbjct: 618 ASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTA---KGTSTYTTTAS 674

Query: 224 PF-----TTCPGSHPVL---------------TAPLSGEPQG----------PPSQPRTH 253
           PF     +  P +HPV                  P++  PQ            P  P++ 
Sbjct: 675 PFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSV 734

Query: 254 STLILQPCGTPDPLQLQPQASGASCLAR-TSGPSEWQLQQEAAEALVGLKDSSQAPRVTP 312
            +  L P GTP   +     S  S LA   S P E   +   A A      SS+      
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATA----SSKGTLTYL 790

Query: 313 SVPPNPAWISLL-HPCGPPAPAGGRG-FQPVGPCLRP 347
           +  P+P  +S+      PP   G  G   P+G    P
Sbjct: 791 ADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSP 827


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 67/252 (26%), Positives = 90/252 (35%), Gaps = 41/252 (16%)

Query: 117 TTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPW 176
           T   Q+P  ++   P P  P    +  P PP     G +  S  P   P       P P 
Sbjct: 247 TAVSQLPPSEKMSQPTPAQPQSFSVGQPQPPPPPVGGAVAQSSAP-LPPFPGAATGPQPM 305

Query: 177 V-------PGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGT-SLQLPTHGPFTTC 228
           +       P    P G ++PP  V      +PA+SLPP PG   G  + Q P    +   
Sbjct: 306 MAAAQPSQPQGAGPGGQTLPPTNVT---LAQPAMSLPPQPGPAVGAPAAQQPQQFAYP-- 360

Query: 229 PGSHPVLTAPLSGEPQGPPS-----QPRTHSTLILQP-CGTPDPLQLQPQASGASCLART 282
                        +PQ PP      QP   S  + Q   G   P   QP ++GA+    T
Sbjct: 361 -------------QPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPAT 407

Query: 283 SGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCG----PPAPAGGRGF 338
           +        Q A+     L  +S  P    +    PA    + PC     PPA  GG   
Sbjct: 408 AATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGG--- 464

Query: 339 QPVGPCLRPSPA 350
             V PCL P+ A
Sbjct: 465 -VVQPCLGPAGA 475



 Score = 29.6 bits (65), Expect = 4.5
 Identities = 61/229 (26%), Positives = 81/229 (35%), Gaps = 52/229 (22%)

Query: 93  AQLKKHLMRRGEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAV--LLAPTPPGKN 150
           AQL     +  EA        + G   P  P+G       P T  G V   L P   G+ 
Sbjct: 424 AQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVP-----PATVGGVVQPCLGPAGAGQP 478

Query: 151 SCGPLLLSHPPE---ASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPP 207
              P     PP+   + PLS   VP GP    H + PG    P  V       PA S+P 
Sbjct: 479 QSVP-----PPQMGGSGPLS--AVPGGP----HAVVPGVPNVPAAV-------PAPSVPS 520

Query: 208 FPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPL 267
                  TS+ +P              + APL+   Q     P + S+ I+Q  G P   
Sbjct: 521 VST----TSVTMPN-------------VPAPLAQSQQLSSHTPVSRSSSIIQHVGLP--- 560

Query: 268 QLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPP 316
            L P    A      S  S++Q Q    + LVG  D ++        PP
Sbjct: 561 -LAPGTHSAPTSLPQSDLSQFQTQ---TQPLVGQVDDTRRKSEPLPQPP 605


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 57/213 (26%), Positives = 70/213 (32%), Gaps = 37/213 (17%)

Query: 144 PTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPV----------- 192
           P P      G   + H P   P  W   PP P   G   PPG   PPP+           
Sbjct: 400 PLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH-PPGHHGPPPMDQYLGSTPVGS 458

Query: 193 -VCRL-----LYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGP 246
            V RL     +   P + + P P   P      P  GP             P   + Q P
Sbjct: 459 GVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL-----------PPWQQQQQQP 507

Query: 247 PSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQ 306
           P  P   S++      +  PL  Q   +  +  A T     WQ QQ AA A  G      
Sbjct: 508 PPPPPPSSSM-----ASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQG 562

Query: 307 APRVTPSVPP--NPAWISLLHPCGPPAPAGGRG 337
            P + P +PP   P       P  PP P G  G
Sbjct: 563 NPTMVP-LPPGVQPPLPPGAPPPPPPPPPGSAG 594


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 54/172 (31%), Positives = 60/172 (34%), Gaps = 27/172 (15%)

Query: 103 GEASPKAPNH-FRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPT---PPGKNSCGP---L 155
           G A P  P   F  G T P+ P G       P  P    +L P    PP +    P   L
Sbjct: 219 GPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVL 278

Query: 156 LLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGT 215
               P    PL   P  P P VPG+  PPG   PPP       Q P     PFP   PG 
Sbjct: 279 FPGQPFGQPPLGPLPPGPPPPVPGYGPPPG--PPPP------QQGPPPPPGPFPPRPPG- 329

Query: 216 SLQLPTHGPFTTCPGSHPVLTAPLSGEPQG-PPSQPRTHSTLILQPCGTPDP 266
               P   P T  P  H      L G P G PP  P  +      P  +  P
Sbjct: 330 ----PLGPPLTLAPPPH------LPGPPPGAPPPAPHVNPAFFPPPTNSGMP 371



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 51/173 (29%), Positives = 56/173 (32%), Gaps = 35/173 (20%)

Query: 123 PSGKENIAPQPQTPHGAVLLAPTPPGKNSC-GPLLLSHPPEASPLSWTPV---------- 171
           P G  + A  PQ   G        PG +   GP     PP   P   TP           
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPP 247

Query: 172 -PPGPWVPGHWLPP--------GFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTH 222
            PPGP  PG  LPP        G   PPPV    L+       PP     PG    +P +
Sbjct: 248 GPPGPPPPGQVLPPPLAGPPNRGDRPPPPV----LFPGQPFGQPPLGPLPPGPPPPVPGY 303

Query: 223 GPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASG 275
           GP    PG  P          QGPP  P         P G P  L   P   G
Sbjct: 304 GP---PPGPPP--------PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPG 345



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 42/128 (32%), Positives = 47/128 (36%), Gaps = 18/128 (14%)

Query: 133 PQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPW---VPGHWLPPGFSMP 189
           P  P G   L P PPG     P     P    P    P PPGP+    PG   PP    P
Sbjct: 280 PGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAP 339

Query: 190 PPVVCRLLYQEPAVSLPPFPG-----FDPGTSLQLPT---HGPFTTCPGSHPVLTAPLSG 241
           PP     L   P  + PP P      F P T+  +PT    GP  T P   P    P   
Sbjct: 340 PP----HLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP---PPYDR 392

Query: 242 EPQGPPSQ 249
              GPP +
Sbjct: 393 GDYGPPGR 400


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 67/241 (27%), Positives = 82/241 (34%), Gaps = 58/241 (24%)

Query: 120  PQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCG-----PLLLSHPPEASPLSWTPVPPG 174
            P  P     I P P  P   +   P PP     G     PL  +  P   PL    +PP 
Sbjct: 1032 PPPPLPGAGIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1088

Query: 175  PWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPV 234
            P +PG  +PP    PPP+        P V +PP P   PG  +  P   P    P   P+
Sbjct: 1089 PPLPGAGIPP----PPPL--------PGVGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPL 1135

Query: 235  LTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEA 294
               P +G P  PP          L   G P P    P   GA        P         
Sbjct: 1136 ---PGAGIPPPPP----------LPRVGIPPP----PPLPGAGIPPPPPLPG-------- 1170

Query: 295  AEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPC----LRPSPA 350
                 G+      P V   +PP P    +  P  PP P  G G  P  P     + P+PA
Sbjct: 1171 ----AGIPPPPPLPGV--GIPPPPPLPGVGIPPPPPLP--GAGIPPPPPLPGMGIPPAPA 1222

Query: 351  P 351
            P
Sbjct: 1223 P 1223



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 69/254 (27%), Positives = 81/254 (31%), Gaps = 52/254 (20%)

Query: 120  PQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCG-----PLLLSHPPEASPLSWTPVPPG 174
            P  P     I P P  P  A+   P PP     G     PL  +  P   PL    +PP 
Sbjct: 933  PLPPLPGAGIPPPPPLPGAAI---PPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPP 989

Query: 175  PWVPGHWLPP-------GFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTT 227
            P +PG  +PP       G   PPP+        P   +PP P   PG  +  P   P   
Sbjct: 990  PPLPGAGIPPPPPLPGAGIPPPPPL--------PGAGIPPPPPL-PGAGIPPPPPLPGAG 1040

Query: 228  CPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQL-------QPQASGASCLA 280
             P   P+   P +G P  PP          L   G P P  L        P   GA    
Sbjct: 1041 IPPPPPL---PGAGIPPPPP----------LPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1087

Query: 281  RTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQP 340
                P            L G+      P     +PP P       P  PP P  G G  P
Sbjct: 1088 PPPLPG---AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPP 1142

Query: 341  VGPCLR---PSPAP 351
              P  R   P P P
Sbjct: 1143 PPPLPRVGIPPPPP 1156



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 66/247 (26%), Positives = 78/247 (31%), Gaps = 75/247 (30%)

Query: 116  GTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGP 175
            G T P +PS      PQP    G  +L P PP                 PL    +PP P
Sbjct: 885  GMTVPTLPS---TAIPQPPPLQGTEMLPPPPP-----------------PLPGAGIPPPP 924

Query: 176  WVPGHW---LPP----GFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTC 228
             +PG     LPP    G   PPP+        P  ++PP P   PG  + LP   P    
Sbjct: 925  PLPGAGILPLPPLPGAGIPPPPPL--------PGAAIPPPPPL-PGAGIPLPPPLPGAGI 975

Query: 229  PGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEW 288
            P   P+   P +G P  PP          L   G P P    P   GA            
Sbjct: 976  PPPPPL---PGAGIPPPPP----------LPGAGIPPP----PPLPGAGI---------- 1008

Query: 289  QLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPS 348
                     L G       P     +PP P       P  PP P  G G  P      P 
Sbjct: 1009 ----PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP--PPPPLPGAGIPP------PP 1056

Query: 349  PAPSVAL 355
            P P   +
Sbjct: 1057 PLPGAGI 1063



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 48/176 (27%), Positives = 59/176 (33%), Gaps = 27/176 (15%)

Query: 103  GEASPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHP-- 160
            G   P  P   R G   P  P     I P P  P   +   P  PG     P  L     
Sbjct: 1137 GAGIPPPPPLPRVGIPPPP-PLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGI 1195

Query: 161  PEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLP 220
            P   PL    +PP P +PG  +PP  + P P         P   +PP P         LP
Sbjct: 1196 PPPPPLPGAGIPPPPPLPGMGIPPAPAPPLP--------PPGTGIPPPPLLPVSGPPLLP 1247

Query: 221  THGPFT-----TCPGSHPVLTAPLSG----EPQGPPSQPRTHSTLILQPCGTPDPL 267
              G  T      C    P L + L G    + +G   QP       ++PC    PL
Sbjct: 1248 QVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQP-------IEPCRPMKPL 1296


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 61/238 (25%), Positives = 74/238 (31%), Gaps = 18/238 (7%)

Query: 117  TTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPW 176
            TT P  P       P   TP   +    TPP      P     PP  +P   T  P  P 
Sbjct: 1435 TTTPSPPITTTTTPPPTTTPSPPISTTTTPP------PTTTPSPPTTTPSPPTTTPSPPT 1488

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSL-----QLPTHGPFTTCPGS 231
                  PP  +  PP    +       +LPP     P T+         T  P TT P +
Sbjct: 1489 TTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1548

Query: 232  HPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQ 291
             P  T  L   P   PS P T +T    P  TP P       S  +    T  P+     
Sbjct: 1549 PPTSTTTL--PPTTTPSPPPT-TTTTPPPTTTPSP-PTTTTPSPPTITTTTPPPTTTPSP 1604

Query: 292  QEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSP 349
                        +   P  TP  PP     + L P   P+P       P  P   PSP
Sbjct: 1605 PTTTTTTPPPTTTPSPPTTTPITPPTST--TTLPPTTTPSPPPTTTTTP-PPTTTPSP 1659



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 61/257 (23%), Positives = 80/257 (31%), Gaps = 34/257 (13%)

Query: 117  TTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLL--LSHPPEAS----PLSWTP 170
            TT P  P       P   TP        TPP   +  P +   + PP  +    P+S T 
Sbjct: 1403 TTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTT 1462

Query: 171  VPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPG 230
             PP    P    PP  +  PP            + PP     P T+  +      TT P 
Sbjct: 1463 TPPPTTTPS---PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPP 1519

Query: 231  S---HPVLTAPLSGEPQGPPSQPRT------HSTLILQPCGTPDPLQLQPQASGASCLAR 281
            +    P  T   +  P   PS P T       ST  L P  TP P    P  +       
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP---PPTTTTTPPPTT 1576

Query: 282  TSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQP- 340
            T  P               +  ++  P  TPS P      +   P   P+P       P 
Sbjct: 1577 TPSPPTTTTPSPPT-----ITTTTPPPTTTPSPPTTTT--TTPPPTTTPSPPTTTPITPP 1629

Query: 341  -----VGPCLRPSPAPS 352
                 + P   PSP P+
Sbjct: 1630 TSTTTLPPTTTPSPPPT 1646



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 41/165 (24%), Positives = 51/165 (30%), Gaps = 13/165 (7%)

Query: 117  TTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGP----------LLLSHPPEASPL 166
            TT P  P+      P   TP        TPP   +  P             + PP  +P 
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1658

Query: 167  SWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFT 226
              T   P P +     PP  + P   +             P P   P + +   T    T
Sbjct: 1659 PPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSST 1718

Query: 227  TCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQP 271
            T P   P  T   +  P   PS P T  T  L P  T  PL   P
Sbjct: 1719 TTPSPPP--TTMTTPSPTTTPSPPTTTMT-TLPPTTTSSPLTTTP 1760



 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 46/162 (28%), Positives = 56/162 (34%), Gaps = 12/162 (7%)

Query: 106  SPKAPNHFRKGTTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASP 165
            +P A       TT P  P+      P   TP        TPP   +  P   +  P   P
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP---P 1565

Query: 166  LSWTPVPPGPWVPGHWLPPGFSMP-PPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGP 224
             + T  PP    P    PP  + P PP +       P  + P  P     T     T  P
Sbjct: 1566 PTTTTTPPPTTTPS---PPTTTTPSPPTITTT--TPPPTTTPSPPTTTTTTPPPTTTPSP 1620

Query: 225  FTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDP 266
             TT P + P  T  L   P   PS P T +T    P  TP P
Sbjct: 1621 PTTTPITPPTSTTTL--PPTTTPSPPPT-TTTTPPPTTTPSP 1659



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 34/125 (27%), Positives = 45/125 (36%), Gaps = 13/125 (10%)

Query: 117  TTQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPW 176
            TT P  P       P   TP   +   P+PP      P   + P  +SP++ T  P    
Sbjct: 1662 TTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP--SSPITTTTTPSSTT 1719

Query: 177  VPGHWLPPGFSM--PPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLP------THGPFTTC 228
             P    PP  +M  P P            +LPP     P T+  LP      T  PF+T 
Sbjct: 1720 TPS---PPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTT 1776

Query: 229  PGSHP 233
              + P
Sbjct: 1777 TPTTP 1781



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 56/209 (26%), Positives = 67/209 (32%), Gaps = 24/209 (11%)

Query: 150  NSCGPL--LLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPP 207
            N C P+   ++ P   SP + TP PP        LPP  +  PP              PP
Sbjct: 1387 NCCWPMDKCITTP---SPPTTTPSPPPTSTTT--LPPTTTPSPPTTTTTTPPPTTTPSPP 1441

Query: 208  F-------PGFDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRTHSTLILQP 260
                    P   P   +   T  P TT P   P  T P    P   PS P T +T    P
Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPTTTPS--PPTTTP--SPPTTTPSPPTT-TTTTPPP 1496

Query: 261  CGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAW 320
              TP P    P    AS    T  P+                 +   P  TP  PP    
Sbjct: 1497 TTTPSPPTTTPITPPAS--TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST- 1553

Query: 321  ISLLHPCGPPAPAGGRGFQPVGPCLRPSP 349
             + L P   P+P       P  P   PSP
Sbjct: 1554 -TTLPPTTTPSPPPTTTTTP-PPTTTPSP 1580



 Score = 33.9 bits (76), Expect = 0.24
 Identities = 61/262 (23%), Positives = 87/262 (33%), Gaps = 56/262 (21%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 4047 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 4096

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTT--------- 227
                  P G   P       +     V+  P P     T  Q PT  P TT         
Sbjct: 4097 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTPTPT 4143

Query: 228  -----CPGSHPVLT------APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGA 276
                  P + P+ T       P     Q P + P T +T +  P  TP   Q  P    +
Sbjct: 4144 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTGPPTHTS 4202

Query: 277  SC----LARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAP 332
            +     L  ++ P E    Q +      L +S+    +  ++PP     S   P  P AP
Sbjct: 4203 TAPIAELTTSNPPPESSTPQTSRSTSSPLTEST---TLLSTLPPAIEMTSTAPPSTPTAP 4259

Query: 333  AGGRGFQPVGPCLRPSPAPSVA 354
                G    G  L P P+ + +
Sbjct: 4260 TTTSG----GHTLSPPPSTTTS 4277



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 1908 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 1957

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 1958 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2001

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2002 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2060

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2061 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2099



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 1977 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2026

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2027 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2070

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2129

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2130 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2168



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2046 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2095

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2096 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2139

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2140 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2198

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2199 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2237



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2115 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2164

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2165 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2208

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2209 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2267

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2268 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2306



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2184 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2233

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2234 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2277

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2278 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2337 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2375



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2253 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2302

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2303 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2346

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2405

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2406 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2444



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2322 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2371

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2372 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2415

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2474

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2475 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2513



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2391 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2440

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2441 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2484

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2543

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2544 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2582



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2460 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2509

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2510 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2553

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2612

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2651



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2529 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2578

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2579 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2622

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2681

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2682 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2720



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2598 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2647

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2648 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2691

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2750

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2751 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2789



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2667 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2716

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2717 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2760

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2819

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2820 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2858



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2736 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2785

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2786 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2829

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2888

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2889 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2927



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2805 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2854

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2855 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2898

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2957

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 2958 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2996



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2923

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2924 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 2967

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3027 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3065



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 2943 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 2992

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 2993 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3036

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3095

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3096 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3134



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3012 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3061

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3062 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3105

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3164

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3165 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3203



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3081 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3130

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3131 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3174

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3233

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3234 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3272



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3150 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3199

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3200 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3243

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3302

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3303 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3341



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3219 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3268

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3269 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3312

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3371

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3372 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3410



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3288 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3337

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3338 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3381

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3440

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3441 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3479



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3357 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3406

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3407 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3450

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3509

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3510 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3548



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3426 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3475

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3476 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3519

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3578

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3579 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3617



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3495 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3544

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3545 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3588

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3647

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3648 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3686



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3564 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3613

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3614 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3657

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3716

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3717 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3755



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3633 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3682

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3683 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3726

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3785

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3786 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3824



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3702 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3751

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3752 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3795

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3854

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3855 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3893



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3771 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3820

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3821 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3864

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3865 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3923

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3924 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3962



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3840 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3889

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3890 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 3933

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 3934 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3992

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 3993 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4031



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3909 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 3958

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 3959 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 4002

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 4003 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4061

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 4062 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4100



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 51/219 (23%), Positives = 69/219 (31%), Gaps = 29/219 (13%)

Query: 118  TQPQVPSGKENIAPQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLSWTP-VPPGPW 176
            T    P+G +     P T    V   PTP G  +         P  +P++ T  V P P 
Sbjct: 3978 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---------PTTTPITTTTTVTPTP- 4027

Query: 177  VPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLT 236
                  P G   P       +     V+  P P     T  Q PT  P TT   +  V  
Sbjct: 4028 -----TPTGTQTPTTTP---ITTTTTVTPTPTP-----TGTQTPTTTPITT---TTTVTP 4071

Query: 237  APLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAE 296
             P     Q P + P T +T +  P  TP   Q        +    T  P+    Q     
Sbjct: 4072 TPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130

Query: 297  ALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGP-PAPAG 334
             +      +  P  T +  P    I+      P P P G
Sbjct: 4131 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4169


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 72/248 (29%), Positives = 83/248 (33%), Gaps = 38/248 (15%)

Query: 112 HFR--KGTTQPQVPSGKENIA-PQPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEASPLS- 167
           HF+  K    P +P+G   +  P P   +G   L P PP   S  P     PP   PL  
Sbjct: 211 HFKMEKPPAPPSLPAGPPGVKRPPPPLMNG---LPPRPPLPESLPP----PPPGGLPLPP 263

Query: 168 ---WTPVPPGPWVPGHWLPP--GFSMPPPVVCRLLYQEPAVSL-PPFPGFDPGTSLQLPT 221
                P P GP  P    PP  G   P PVV       PA  + PP PG  P      P 
Sbjct: 264 MPPTGPAPSGPPGPPQLPPPAPGVHPPAPVV-----HPPASGVHPPAPGVHP------PA 312

Query: 222 HGPFTTCPGSHPVLTAPLSG-EPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLA 280
            G     PG HP    P SG  P  P   P         P   P    + P A G     
Sbjct: 313 PGVHPPAPGVHP----PTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPP 368

Query: 281 RTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQP 340
                 +      AA A+       QAP V P  P        +HP  P       G  P
Sbjct: 369 SAGVHPQAPGVHPAAPAV-----HPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHP 423

Query: 341 VGPCLRPS 348
             P + PS
Sbjct: 424 QPPGVHPS 431



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 55/184 (29%), Positives = 64/184 (34%), Gaps = 31/184 (16%)

Query: 172 PPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAV--SLPPFPGFDPGTSLQLPTHGPFTTCP 229
           P  P +P    PPG   PPP +   L   P +  SLPP P   PG  L LP   P    P
Sbjct: 218 PAPPSLPAG--PPGVKRPPPPLMNGLPPRPPLPESLPPPP---PG-GLPLPPMPPTGPAP 271

Query: 230 GSHPVLTAPLSGEPQGPPSQPRTHSTLILQPCGTPDPLQLQPQASGASCLARTSGPSEWQ 289
              P       G PQ PP  P  H          P P+ + P ASG    A    P    
Sbjct: 272 SGPP-------GPPQLPPPAPGVHP---------PAPV-VHPPASGVHPPAPGVHPPAPG 314

Query: 290 LQQEAAEALVGLKDSSQAPRVTPSVPPNPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSP 349
           +   A    V    S   P      PP P     +HP  P       G  P  P + P P
Sbjct: 315 VHPPAPG--VHPPTSGVHPPAPGVHPPAPG----VHPPAPGVHPPAPGVHPPAPGVHPPP 368

Query: 350 APSV 353
           +  V
Sbjct: 369 SAGV 372



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 31/93 (33%), Positives = 36/93 (38%), Gaps = 13/93 (13%)

Query: 107 PKAPN-HFRKGTTQPQVPSGKENIAP--QPQTPHGAVLLAPTPPGKNSCGPLLLSHPPEA 163
           P+AP  H       PQ P G    AP   PQ P     + P PPG +   P +   PP  
Sbjct: 374 PQAPGVHPAAPAVHPQAP-GVHPPAPGMHPQAPG----VHPQPPGVHPSAPGVHPQPPGV 428

Query: 164 SPLSWTPVPPGPWVPGHWLP-----PGFSMPPP 191
            P +    PP P  P    P     PG   PPP
Sbjct: 429 HPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPP 461


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 66/274 (24%), Positives = 94/274 (34%), Gaps = 42/274 (15%)

Query: 90   QQEAQLKKHLMRRGEASPKAPNHFRKGTTQPQVPSGKENIA-PQPQTP----HGAVLLAP 144
            +  A LK+ +  +            +  T  + P  KE  A P+P  P    H       
Sbjct: 1119 EASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVR 1178

Query: 145  TPPGKNSCGPLLLSHPP---EASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEP 201
              P     GP  L  PP   E  P     +PP P   G    P     PPV  + +  +P
Sbjct: 1179 RRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPA---KPPVSPKPVLTQP 1235

Query: 202  AVSLPPFPGFDPGTSLQLPTHGPFTTCPGSHPVLTA-----PLSGEPQGPPSQPRTHSTL 256
               +P   G    TS ++P  GP     GS  V  A     P+S +P  PP+ P+    +
Sbjct: 1236 ---VPKLQGSPTPTSKKVPLPGP-----GSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAV 1287

Query: 257  ILQPCGTPDPLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPP 316
               P G+  P    P  S A               ++   AL     +  +   +P+ PP
Sbjct: 1288 AGLPSGSAGP---SPAPSPA---------------RQPPAALAKPPGTPPSLGASPAKPP 1329

Query: 317  NPAWISLLHPCGPPAPAGGRGFQPVGPCLRPSPA 350
            +P   +L  P  PP  A         P   P  A
Sbjct: 1330 SPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGA 1363



 Score = 32.0 bits (71), Expect = 0.90
 Identities = 41/140 (29%), Positives = 49/140 (35%), Gaps = 29/140 (20%)

Query: 141 LLAPTPPGKNSCGPLLLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQE 200
           LL   PPG +S        P   S        P P  P     PG         R  +  
Sbjct: 709 LLGDGPPGPSS--------PMSRSQEYLLDEGPAPGTPPREARPG---------RHGHSI 751

Query: 201 PAVSLPPFPG-----FDPGTSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGP-PSQPRTHS 254
              S+PP PG       PGTS   P   P  T PGS   L     G P GP P+  +   
Sbjct: 752 KRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQAL-----GGPHGPAPATAKVKP 806

Query: 255 T-LILQPCGTPDPLQLQPQA 273
           T  +L P   P   +  PQ+
Sbjct: 807 TPQLLPPTERPMSPRSLPQS 826


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,508,352
Number of Sequences: 37866
Number of extensions: 1650673
Number of successful extensions: 10498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 977
Number of HSP's that attempted gapping in prelim test: 7286
Number of HSP's gapped (non-prelim): 3163
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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