Guide to the Human Genome
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Name: GPX4 Sequence: fasta or formatted (234aa) NCBI GI: 90903240
Description:

glutathione peroxidase 4 isoform C precursor

Referenced in:

Glutathione Pathways
Selenium Proteins

Other entries for this name:
alt prot [197aa] glutathione peroxidase 4 isoform A precursor
alt prot [227aa] glutathione peroxidase 4 isoform B precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3         17           2
 C cysteine            4.7         11           1
 D aspartate           5.1         12           2
 E glutamate           5.1         12           2
 F phenylalanine       4.3         10           1
 G glycine             7.7         18           1
 H histidine           2.6          6           1
 I isoleucine          4.7         11           1
 K lysine              8.5         20           2
 L leucine             4.7         11           1
 M methionine          2.6          6           1
 N asparagine          4.3         10           1
 P proline             6.8         16           1
 Q glutamine           3.4          8           1
 R arginine           12.8         30           4
 S serine              4.3         10           1
 T threonine           1.7          4           1
 U selenocysteine      0.4          1           1
 V valine              4.7         11           2
 W tryptophan          1.7          4           1
 Y tyrosine            2.6          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   glutathione peroxidase 4 isoform C precursor 
GPX4                  0.711   glutathione peroxidase 4 isoform A precursor 
GPX4                  0.580   glutathione peroxidase 4 isoform B precursor 
GPX7                  0.192   glutathione peroxidase 7 
GPX8                  0.175   glutathione peroxidase 8 
GPX1                  0.158   glutathione peroxidase 1 isoform 1 
GPX2                  0.141   glutathione peroxidase 2 
GPX3                  0.120   glutathione peroxidase 3 precursor 
GPX5                  0.105   glutathione peroxidase 5 isoform 1 precursor 
GPX6                  0.105   glutathione peroxidase 6 
GPX1                  0.076   glutathione peroxidase 1 isoform 2 
SFRS11                0.036   splicing factor, arginine/serine-rich 11 
SNRNP27               0.032   small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Ho...
LOC100170229          0.030   hypothetical protein LOC100170229 
SFRS12                0.027   splicing factor, arginine/serine-rich 12 isoform a ...
SFRS12                0.027   splicing factor, arginine/serine-rich 12 isoform b [...
LOC100291243          0.025   PREDICTED: hypothetical protein XP_002348077 
LOC100288603          0.025   PREDICTED: hypothetical protein XP_002343773 
LOC100294073          0.025   PREDICTED: hypothetical protein, partial 
SRRM1                 0.025   serine/arginine repetitive matrix 1 
FLJ37078              0.023   hypothetical protein LOC222183 
LOC731605             0.021   PREDICTED: similar to BCL2-associated transcription...
LOC100293578          0.021   PREDICTED: hypothetical protein 
LOC100290886          0.021   PREDICTED: hypothetical protein XP_002346949 
LOC100286960          0.021   PREDICTED: hypothetical protein XP_002342813 
LOC100286960          0.021   PREDICTED: hypothetical protein 
FLJ36031              0.021   hypothetical protein LOC168455 
PRM2                  0.021   protamine 2 
LOC100292733          0.021   PREDICTED: similar to predicted protein 
LOC731605             0.021   PREDICTED: similar to BCL2-associated transcription...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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