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Search of human proteins with 90819233
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|90819233 myeloid/lymphoid or mixed-lineage leukemia
(trithorax homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
(1651 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3315 0.0
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3293 0.0
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 3174 0.0
gi|148746195 trichohyalin [Homo sapiens] 85 7e-16
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 79 3e-14
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 77 1e-13
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 77 2e-13
gi|148612825 Rap GTPase interactor [Homo sapiens] 75 4e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 74 9e-13
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 73 2e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 72 4e-12
gi|148746189 multiple PDZ domain protein [Homo sapiens] 72 4e-12
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 72 6e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 71 1e-11
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 71 1e-11
gi|93204861 protein phosphatase 1, regulatory (inhibitor) subuni... 70 1e-11
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 70 2e-11
gi|112382257 InaD-like [Homo sapiens] 69 3e-11
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 69 4e-11
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 69 4e-11
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 69 4e-11
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 69 4e-11
gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo ... 69 5e-11
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 68 6e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 68 8e-11
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 67 1e-10
gi|87196343 PDZ domain containing 2 [Homo sapiens] 67 1e-10
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 67 2e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 66 3e-10
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i... 66 3e-10
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 3315 bits (8596), Expect = 0.0
Identities = 1651/1651 (100%), Positives = 1651/1651 (100%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 180
DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA
Sbjct: 121 DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 180
Query: 181 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 240
SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS
Sbjct: 181 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 240
Query: 241 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 300
DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV
Sbjct: 241 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 300
Query: 301 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 360
MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE
Sbjct: 301 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 360
Query: 361 GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR 420
GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR
Sbjct: 361 GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR 420
Query: 421 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 480
LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET
Sbjct: 421 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 480
Query: 481 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 540
TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI
Sbjct: 481 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 540
Query: 541 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 600
HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI
Sbjct: 541 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 600
Query: 601 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 660
LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT
Sbjct: 601 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 660
Query: 661 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 720
HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA
Sbjct: 661 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 720
Query: 721 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 780
HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA
Sbjct: 721 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 780
Query: 781 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 840
ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD
Sbjct: 781 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 840
Query: 841 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 900
CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE
Sbjct: 841 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 900
Query: 901 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 960
NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC
Sbjct: 901 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 960
Query: 961 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1020
QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL
Sbjct: 961 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1020
Query: 1021 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1080
SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR
Sbjct: 1021 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1080
Query: 1081 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1140
TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS
Sbjct: 1081 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1140
Query: 1141 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1200
PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV
Sbjct: 1141 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1200
Query: 1201 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1260
STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT
Sbjct: 1201 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1260
Query: 1261 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1320
DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE
Sbjct: 1261 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1320
Query: 1321 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1380
HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD
Sbjct: 1321 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1380
Query: 1381 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1440
GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK
Sbjct: 1381 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1440
Query: 1441 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1500
LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV
Sbjct: 1441 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1500
Query: 1501 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1560
SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL
Sbjct: 1501 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1560
Query: 1561 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKR 1620
MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKR
Sbjct: 1561 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKR 1620
Query: 1621 EAEDRARQEEERRRQEEERTKRDAEEKVMVL 1651
EAEDRARQEEERRRQEEERTKRDAEEKVMVL
Sbjct: 1621 EAEDRARQEEERRRQEEERTKRDAEEKVMVL 1651
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 3293 bits (8538), Expect = 0.0
Identities = 1646/1660 (99%), Positives = 1646/1660 (99%), Gaps = 14/1660 (0%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 180
DREGRFVLKNENDAIPPK AQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA
Sbjct: 121 DREGRFVLKNENDAIPPK-AQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 179
Query: 181 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 240
SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS
Sbjct: 180 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 239
Query: 241 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 300
DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV
Sbjct: 240 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 299
Query: 301 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 360
MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE
Sbjct: 300 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 359
Query: 361 GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR 420
GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR
Sbjct: 360 GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR 419
Query: 421 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 480
LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET
Sbjct: 420 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 479
Query: 481 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 540
TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI
Sbjct: 480 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 539
Query: 541 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 600
HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI
Sbjct: 540 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 599
Query: 601 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 660
LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT
Sbjct: 600 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 659
Query: 661 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 720
HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA
Sbjct: 660 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 719
Query: 721 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 780
HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA
Sbjct: 720 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 779
Query: 781 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 840
ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD
Sbjct: 780 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 839
Query: 841 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 900
CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE
Sbjct: 840 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 899
Query: 901 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 960
NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC
Sbjct: 900 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 959
Query: 961 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1020
QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL
Sbjct: 960 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1019
Query: 1021 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1080
SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR
Sbjct: 1020 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1079
Query: 1081 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1140
TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS
Sbjct: 1080 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1139
Query: 1141 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1200
PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV
Sbjct: 1140 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1199
Query: 1201 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1260
STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT
Sbjct: 1200 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1259
Query: 1261 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1320
DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE
Sbjct: 1260 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1319
Query: 1321 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1380
HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD
Sbjct: 1320 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1379
Query: 1381 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1440
GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK
Sbjct: 1380 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1439
Query: 1441 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1500
LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV
Sbjct: 1440 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1499
Query: 1501 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1560
SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL
Sbjct: 1500 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1559
Query: 1561 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR-------------DEE 1607
MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR DEE
Sbjct: 1560 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARTAMPAISVLDLLQDEE 1619
Query: 1608 RRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1647
RRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK
Sbjct: 1620 RRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1659
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 3174 bits (8230), Expect = 0.0
Identities = 1588/1604 (99%), Positives = 1588/1604 (99%), Gaps = 16/1604 (0%)
Query: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI
Sbjct: 1 MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCI 60
Query: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD
Sbjct: 61 RVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKD 120
Query: 121 DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 180
DREGRFVLKNENDAIPPK AQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA
Sbjct: 121 DREGRFVLKNENDAIPPK-AQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 179
Query: 181 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 240
SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS
Sbjct: 180 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSS 239
Query: 241 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 300
DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV
Sbjct: 240 DGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARV 299
Query: 301 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 360
MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE
Sbjct: 300 MLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLE 359
Query: 361 GKTPKGKERADGSGYGSTLPPEKLPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYR 420
GKTPKGKERADGSGYGSTLPPEKLPYLVELSP DGSDSRDKPKLYR
Sbjct: 360 GKTPKGKERADGSGYGSTLPPEKLPYLVELSP---------------DGSDSRDKPKLYR 404
Query: 421 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 480
LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET
Sbjct: 405 LQLSVTEVGTEKLDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISET 464
Query: 481 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 540
TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI
Sbjct: 465 TMLQSGMKVQFGASHVFKFVDPSQDHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDI 524
Query: 541 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 600
HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI
Sbjct: 525 HSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPELI 584
Query: 601 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 660
LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT
Sbjct: 585 LPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERT 644
Query: 661 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 720
HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA
Sbjct: 645 HKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLA 704
Query: 721 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 780
HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA
Sbjct: 705 HLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNA 764
Query: 781 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 840
ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD
Sbjct: 765 ALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAAD 824
Query: 841 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 900
CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE
Sbjct: 825 CHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIE 884
Query: 901 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 960
NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC
Sbjct: 885 NVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLC 944
Query: 961 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1020
QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL
Sbjct: 945 QRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGL 1004
Query: 1021 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1080
SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR
Sbjct: 1005 SIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTR 1064
Query: 1081 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1140
TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS
Sbjct: 1065 TSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGS 1124
Query: 1141 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1200
PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV
Sbjct: 1125 PESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITSV 1184
Query: 1201 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1260
STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT
Sbjct: 1185 STGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWPNYEEKPHMHT 1244
Query: 1261 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1320
DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE
Sbjct: 1245 DSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQE 1304
Query: 1321 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1380
HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD
Sbjct: 1305 HLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFD 1364
Query: 1381 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1440
GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK
Sbjct: 1365 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1424
Query: 1441 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1500
LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV
Sbjct: 1425 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1484
Query: 1501 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1560
SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL
Sbjct: 1485 SKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL 1544
Query: 1561 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1604
MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR
Sbjct: 1545 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1588
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 84.7 bits (208), Expect = 7e-16
Identities = 72/247 (29%), Positives = 130/247 (52%), Gaps = 29/247 (11%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQER------KLGQMRTQSLNPAPFSPLTAQQ 1461
ER+ REE Q E+E+ EE +R+R+E+ER KL Q Q L P ++
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986
Query: 1462 MKP-EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1520
K + LQ+ +E ++RE + +++ + ER+ + + +EE + R+
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEE---------EQLLREE 1037
Query: 1521 KEKLEKQQQMHIVDMLSKEIQELQSKPDRS-AEESDRLRKLMLEWQFQKRLQESKQKDED 1579
+EK Q++ + +E +ELQ + ++ EE + R+ LE Q++K +E +Q++E
Sbjct: 1038 REKRRLQER----ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE-EELQQEEEQ 1092
Query: 1580 DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEER 1639
EE + +R E ER+ R+EE +Q++ E++ + E E R RQE ER+ +EEE
Sbjct: 1093 LLREEPEK------RRRQERERQCREEEELQQEE-EQLLREEREKRRRQELERQYREEEE 1145
Query: 1640 TKRDAEE 1646
+++ E+
Sbjct: 1146 VQQEEEQ 1152
Score = 79.7 bits (195), Expect = 2e-14
Identities = 66/267 (24%), Positives = 132/267 (49%), Gaps = 32/267 (11%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRR------------EQERKLGQMRTQSLNPAPFS 1455
+ R+R + QR +K + +LEEER+R+R +E++L Q + L
Sbjct: 860 QERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREERE 919
Query: 1456 PLTAQQMKPE--KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1513
Q+ + + + LQ+ +E ++RE +++ R + R+ QY K + L
Sbjct: 920 KRRRQEQERQYREEEQLQQEEEQLLRE---EREKRRRQERERQYRKDKKLQQKEEQLLGE 976
Query: 1514 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRK----------LMLE 1563
+P KR +E+ +K ++ + +++ + + R E + RK L+ E
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 1564 WQFQKRLQESKQKDEDDEEEEDDDVDTM----LIMQRLEAERRARDEERRRQQQLEEMRK 1619
+ ++RLQE +++ ++EE + ++ + +R E ER+ R EE +Q++ E++ +
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE-EQLLR 1095
Query: 1620 REAEDRARQEEERRRQEEERTKRDAEE 1646
E E R RQE ER+ +EEE +++ E+
Sbjct: 1096 EEPEKRRRQERERQCREEEELQQEEEQ 1122
Score = 79.3 bits (194), Expect = 3e-14
Identities = 71/244 (29%), Positives = 121/244 (49%), Gaps = 34/244 (13%)
Query: 1410 RKREEHQRWYEKEKARLEEE----RERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1465
R++EE QR +E +LEEE R +KR+EQER+L + QS Q+ E
Sbjct: 113 RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEE 172
Query: 1466 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1525
Q QE R + +Q ++ +E+L + L +R +E E
Sbjct: 173 LWRQRQEWQEREERRAEEEQLQSCKGHETEEF--PDEEQLRRRELLE---LRRKGRE--E 225
Query: 1526 KQQQMHIVDMLSKEIQELQSKPDRSAEESD-RLRKLMLEWQFQKRLQESKQKDEDDEEEE 1584
KQQQ +E Q + + EE + R R+ +L + +K +E Q+ + +EEE
Sbjct: 226 KQQQR----------RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEE 275
Query: 1585 DDDVDTMLIMQRLEAE--RRARDEERRRQQQL---EEMRKREAEDRARQEEERRRQEEER 1639
+ +++LE + RR R EE ++QQ+L +++R+++ E+R Q+EERR Q+E R
Sbjct: 276 EQ-------LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 1640 TKRD 1643
+++
Sbjct: 329 EQQE 332
Score = 79.3 bits (194), Expect = 3e-14
Identities = 67/258 (25%), Positives = 130/258 (50%), Gaps = 51/258 (19%)
Query: 1408 ERRKREEHQRWY-------EKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQ 1460
E+R+R+E ++ Y ++E+ L EERE++RR++
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE----------------------W 1016
Query: 1461 QMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEEL-SSGDSLSPDPWKRD 1519
+ + K LQ+ +E ++RE +++ R ++ R+ QY +EEL + L + +
Sbjct: 1017 ERQYRKKDELQQEEEQLLRE---EREKRRLQERERQY--REEEELQQEEEQLLGEERETR 1071
Query: 1520 AKEKLEKQQQMHIVDMLSKEIQELQSKPD-----------RSAEESDRLRKLMLEWQFQK 1568
+++LE+Q + ++ +E Q L+ +P+ R EE + + +L + +K
Sbjct: 1072 RRQELERQYRKE-EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREK 1130
Query: 1569 RLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQ 1628
R ++ ++ +EEE + + +L R E E+R R E R+ ++ EE+++ E E R+
Sbjct: 1131 RRRQELERQYREEEEVQQEEEQLL---REEPEKRRRQELERQYREEEELQQEE-EQLLRE 1186
Query: 1629 EEERRRQEEERTKRDAEE 1646
E+E+RRQE ER R+ EE
Sbjct: 1187 EQEKRRQERERQYREEEE 1204
Score = 78.6 bits (192), Expect = 5e-14
Identities = 69/278 (24%), Positives = 137/278 (49%), Gaps = 44/278 (15%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERE------RKRREQERKLGQMRTQSLNPAPFSPLTAQQ 1461
E+R+R+E +R Y K+K ++E + KRR QER+ + L L ++
Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER 1008
Query: 1462 MKPE---------KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS-L 1511
K K LQ+ +E ++RE +++ R ++ R+ QY +EEL + L
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEEEQLLRE---EREKRRLQERERQYR--EEEELQQEEEQL 1063
Query: 1512 SPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPD-----------RSAEESDRLRKL 1560
+ + +++LE+Q + ++ +E Q L+ +P+ R EE + +
Sbjct: 1064 LGEERETRRRQELERQYRKE-EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122
Query: 1561 MLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQ-----RLEAERRARDEERRRQQQLE 1615
+L + +KR ++ ++ +EEE + + +L + R E ER+ R+EE +Q++ +
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQ 1182
Query: 1616 ------EMRKREAEDRARQEEERRRQEEERTKRDAEEK 1647
E R++E E + R+EEE +RQ+ ++ RD +++
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Score = 78.2 bits (191), Expect = 6e-14
Identities = 69/260 (26%), Positives = 124/260 (47%), Gaps = 31/260 (11%)
Query: 1408 ERRKREEHQRWYEKEKARLEEE----RERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1463
+RR+ E+ QR +E +LEEE R +KR+EQER+L + QS Q+
Sbjct: 112 DRRQEED-QRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170
Query: 1464 PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK 1523
E Q QE R + +Q ++ +E+L + L R+ K++
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEF--PDEEQLRRRELLELRRKGREEKQQ 228
Query: 1524 LEKQQQMHIVD------------MLSKEIQELQ-SKPDRS---AEESDRLRKLMLEWQFQ 1567
+++Q + +L KE ++LQ +P R EE ++LRKL + +
Sbjct: 229 QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR 288
Query: 1568 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRAR 1627
+R +E +Q+ E++ + ++ E ERR + EERR QQ+ E ++ E + R
Sbjct: 289 ERQEEEQQQQRLRREQQ--------LRRKQEEERREQQEERREQQERREQQEERREQQLR 340
Query: 1628 QEEERRRQEEERTKRDAEEK 1647
+E+E RR+++ R +++ E +
Sbjct: 341 REQEERREQQLRREQEEERR 360
Score = 76.6 bits (187), Expect = 2e-13
Identities = 69/280 (24%), Positives = 132/280 (47%), Gaps = 32/280 (11%)
Query: 1396 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRRE-----QERKLGQMRTQSLN 1450
Q G Q +RR+RE +W E+E+A +++ E +RR+ Q + + Q L+
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 1451 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIER---RDLQYITVSKEELS- 1506
P PL Q+ + + Q+ ++ + E + ++Q R R ++LQ++ +E+L
Sbjct: 786 ARP--PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE-EEEQLQR 842
Query: 1507 ---------SGDSLSPDPWKRDAKEKLEKQQ-QMHIVDMLSKEIQELQSKP---DRSAEE 1553
D L D +R ++E+ Q+ + + + + L +KP ++ +E
Sbjct: 843 RERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKE 902
Query: 1554 SDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRR--- 1610
L++ E Q ++R + +Q+ E EE+ + R E E+R R E R+
Sbjct: 903 QQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRK 962
Query: 1611 ----QQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEE 1646
QQ+ E++ E E R RQE E++ +EEE +++ E+
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQ 1002
Score = 76.3 bits (186), Expect = 2e-13
Identities = 65/276 (23%), Positives = 127/276 (46%), Gaps = 46/276 (16%)
Query: 1410 RKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1469
++ E +RW + E+ E++ER+ ++ R+ + R Q L Q+++ E+
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQ-- 537
Query: 1470 LQRPQETVIRELQPQQQPRTIER-RDLQYITVSKEE-----LSSGDSLSPDPWKRDAKEK 1523
L+R QE +L +++ + +E+ R Q + +EE L + KR+ +E+
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Query: 1524 LEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEE 1583
LE++ + V+ L +E + Q EE R + L E Q ++R Q+ +++ ++ E+
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Query: 1584 ----EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDR-------------- 1625
E+++ +RLE + EE RR+Q+L E + +A +R
Sbjct: 658 RLKREEEE-------ERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES 710
Query: 1626 -------------ARQEEERRRQEEERTKRDAEEKV 1648
+QE +RRRQE+E +R E ++
Sbjct: 711 EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Score = 75.1 bits (183), Expect = 5e-13
Identities = 66/249 (26%), Positives = 124/249 (49%), Gaps = 20/249 (8%)
Query: 1409 RRKREEH----QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1464
RR+R+E QR +++ R ++E ER+ +++ER+ Q R + L +Q +
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ-EE 345
Query: 1465 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1524
+ L+R QE RE Q +++ ERR+ Q +++L L + R +++L
Sbjct: 346 RREQQLRREQEEERREQQLRREQEE-ERREQQ--LRREQQLRREQQLRREQQLR-REQQL 401
Query: 1525 EKQQQMHIVDMLSKEIQ---ELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQ---KDE 1578
++QQ+ L +E Q E Q + ++ E ++ + Q KR QE ++ K E
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKRE 461
Query: 1579 DDEEEEDDDVDTMLIMQRLEAERRAR-----DEERRRQQQLEEMRKREAEDRARQEEERR 1633
++ E + + + + E ERR R +EERR QQ+ E + R ++ R++ +R
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 1634 RQEEERTKR 1642
++EEER ++
Sbjct: 522 QEEEERLQQ 530
Score = 75.1 bits (183), Expect = 5e-13
Identities = 66/255 (25%), Positives = 129/255 (50%), Gaps = 32/255 (12%)
Query: 1409 RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPS 1468
RRK+EE +R ++E+ E++ER+ +++ER+ Q+R + L +Q + +
Sbjct: 307 RRKQEEERREQQEER---REQQERREQQEERREQQLRREQEERRE-QQLRREQEEERREQ 362
Query: 1469 TLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQ 1528
L+R QE RE Q +++ + + L+ +++L L + R +++L ++Q
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLR----REQQLRREQQLRREQQLR-REQQLRREQ 417
Query: 1529 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQ----FQKRLQESKQKDED----- 1579
Q+ L +E +E + ++ E+ R ++L E + + KR +E+++ +++
Sbjct: 418 QLRREQQLRREQEE--ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQ 475
Query: 1580 ---DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQE 1636
D+EEE + +LE E R +ERR QQ E +R + RQEEE R Q+
Sbjct: 476 LKRDQEEERRE-----RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 1637 ----EERTKRDAEEK 1647
E++ +R+ EE+
Sbjct: 531 RLRSEQQLRREQEER 545
Score = 74.3 bits (181), Expect = 9e-13
Identities = 71/283 (25%), Positives = 126/283 (44%), Gaps = 44/283 (15%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
E RKRE R E++ E +R+R+ +E+E +L ++ Q L QQ + +
Sbjct: 245 EWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE-EQQQQRLRRE 303
Query: 1468 STLQRPQETVIRELQP-----------------QQQPRTIERRDLQYITVSKEELSSGDS 1510
L+R QE RE Q QQ R E R Q + +EE
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 1511 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL 1570
L + + +++L ++QQ+ L +E Q + + R ++ R ++L E Q ++
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 423
Query: 1571 QESKQKDEDDEEEEDDDVDTMLIMQRLEAERR----------ARDEERRRQQ-------- 1612
Q ++++E+ E++ + ++R + ERR ++ERR+QQ
Sbjct: 424 QLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEE 483
Query: 1613 ------QLEEMRKREAEDRARQEEERRRQE--EERTKRDAEEK 1647
+LEE +RE ++R Q+ R ++E E+R KR EE+
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEE 526
Score = 73.6 bits (179), Expect = 2e-12
Identities = 57/241 (23%), Positives = 115/241 (47%), Gaps = 23/241 (9%)
Query: 1408 ERRKREEHQRWYEKEKAR-LEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1466
ERRK++ + E+ + R L+ E E +R +QER+ Q+R + Q+ + E+
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE------------QEERREQ 517
Query: 1467 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1526
Q +E + + L+ +QQ R + + + +EE KR+ +E+ ++
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Query: 1527 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1586
+L +E + Q + R EE RL + + + ++ QE +++ EE ++
Sbjct: 578 --------LLKREEERRQQRLKREQEE--RLEQRLKREEVERLEQEERREQRLKREEPEE 627
Query: 1587 DVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEE 1646
+ L+ + ERR + R +Q++ E+ KRE E+ ++ +R EEER +++ E
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 1647 K 1647
+
Sbjct: 688 E 688
Score = 72.4 bits (176), Expect = 3e-12
Identities = 69/271 (25%), Positives = 133/271 (49%), Gaps = 42/271 (15%)
Query: 1408 ERRKREEH-----QRWYEKEKARLEEERERK---RREQERKLGQMRTQSLNPAPFSPLTA 1459
+R KR+E QR +++ R E+E R+ +RE+E++L Q R +
Sbjct: 517 QRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRD 576
Query: 1460 QQMKPE---KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1516
Q +K E + L+R QE + + +++ +E+ + + + +EE P+
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE--------PEEE 628
Query: 1517 KRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRL-RKLMLEWQFQKRLQESKQ 1575
+R K E+Q++ L +E QE + + + EE +RL ++L E + ++R QE +
Sbjct: 629 RRQQLLKSEEQEERR-QQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 1576 KDEDDEEEE------------DDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAE 1623
++++ E + + D ++ + R ++ +RRRQ+Q E+ R+RE+E
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADAR--QSKVYSRPRKQEGQRRRQEQEEKRRRRESE 745
Query: 1624 DRARQEEE-RRRQEEERTKRD------AEEK 1647
+ ++EE R+Q+EE +RD AEEK
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEK 776
Score = 72.0 bits (175), Expect = 4e-12
Identities = 68/253 (26%), Positives = 126/253 (49%), Gaps = 32/253 (12%)
Query: 1408 ERRKREEHQRWYEKEKARLE-EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1466
+R+ REE Q E E+ +L +ER+RK RE+E++L + + L Q+++ +
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 1467 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1526
Q QET +L+ Q++ R I + +++L + RD K + E+
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE--------RDRKFREEE 1777
Query: 1527 QQQMHIVDMLSKEIQELQSKP-DRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEED 1585
Q + +E Q+L+S+ DR E ++LR+ E Q + + ++ K + E+++ + +
Sbjct: 1778 QLRQE------REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Query: 1586 DDVDTMLIMQRLEAERRARDEE--------RRRQQQL----EEMRKREAEDRARQEEERR 1633
+ + R E +R+ R EE RR +Q+L E+ R++E E + R+E RR
Sbjct: 1832 EQEQRL----RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRR 1887
Query: 1634 RQEEERTKRDAEE 1646
+Q+EE+ R E
Sbjct: 1888 QQKEEQRHRQVGE 1900
Score = 71.6 bits (174), Expect = 6e-12
Identities = 61/249 (24%), Positives = 131/249 (52%), Gaps = 31/249 (12%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1462
Q+ ++ +RE+ R ++ + EEER ++ EQER+ +++ +
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE--------------- 450
Query: 1463 KPEKPSTLQRPQETVIRELQPQQQ----PRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1518
+ E+ L+R +ET E + ++Q + ERR+ +++ + +EE +R
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRE-RWLKLEEEERREQQERREQQLRR 509
Query: 1519 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDE 1578
+ +E+ ++Q++ + + Q L+S+ E+ +R R+ +L+ + +KRL E +++++
Sbjct: 510 EQEER--REQRLKRQEEEERLQQRLRSEQQLRREQEER-REQLLKREEEKRL-EQERREQ 565
Query: 1579 DDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEE 1638
+ E+++ D +L + E ERR + +R ++++LE+ KRE +R QEE R E+
Sbjct: 566 RLKREQEERRDQLL---KREEERRQQRLKREQEERLEQRLKREEVERLEQEERR----EQ 618
Query: 1639 RTKRDAEEK 1647
R KR+ E+
Sbjct: 619 RLKREEPEE 627
Score = 71.6 bits (174), Expect = 6e-12
Identities = 64/255 (25%), Positives = 122/255 (47%), Gaps = 25/255 (9%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRRE-------QERKLGQMRTQSLNPAPFSPLTAQ 1460
ER+ REE + E+E+ L EERE++RR+ +E ++ Q Q L P +
Sbjct: 1107 ERQCREEEELQQEEEQL-LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE 1165
Query: 1461 -QMKPEKPSTLQRPQETVIRELQP---QQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1516
+ + + LQ+ +E ++RE Q Q++ R + K+ D S W
Sbjct: 1166 LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 1517 K-RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESK- 1574
+ KE + +++ +++ ++L+ R + L+ L+ E Q + R QE +
Sbjct: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRR 1285
Query: 1575 --QKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEER 1632
Q+D EEE ++R E ++ A+ +R+ Q++ + +R+ E R RQE +R
Sbjct: 1286 WQQRDRHFPEEEQ--------LER-EEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 1633 RRQEEERTKRDAEEK 1647
+ +EEE+ ++ EE+
Sbjct: 1337 KFREEEQLLQEREEQ 1351
Score = 70.9 bits (172), Expect = 1e-11
Identities = 57/245 (23%), Positives = 127/245 (51%), Gaps = 22/245 (8%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
++++RE R +++E+ + +RE R++E KL + P ++++ E+
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE----------PQRQRELQEEEE 276
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1527
+ ++ + RE Q ++Q + RR+ Q +EE +R+ +E+ E+Q
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEE-----RREQQERREQQ 331
Query: 1528 QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDD 1587
++ + ++ + + + R EE R ++L E + ++R Q+ +++ + E++
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 1588 VDTMLIMQRLEAERRARDEER-RRQQQL---EEMRKREAEDRARQE-EERRRQEEERTKR 1642
+ Q+L E++ R E++ RR+QQL +++R+ + E+R Q+ E+ RR E+R KR
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR--EQRLKR 449
Query: 1643 DAEEK 1647
+ EE+
Sbjct: 450 EQEER 454
Score = 70.5 bits (171), Expect = 1e-11
Identities = 59/246 (23%), Positives = 123/246 (50%), Gaps = 25/246 (10%)
Query: 1406 AAERRKREEHQRWYEKEKARLEEERERKRRE-QERKLGQMRTQSLNPAPFSPLTAQQMKP 1464
A + E+ +R ++++ R +EE R+R+E QER+ + + L + P
Sbjct: 149 AEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH---ETEEFP 205
Query: 1465 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1524
++ +R + R+ + ++Q + ER+D + ++E +++ R +EKL
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV-----LRKEEEKL 260
Query: 1525 EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL---QESKQKDEDDE 1581
++++ +E+QE + + R E + R+ E Q Q+RL Q+ ++K E++
Sbjct: 261 QEEEPQR-----QRELQE-EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 1582 EEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTK 1641
E+ ++ +R + ERR + EERR QQ E +R + R++EE RR+++ R +
Sbjct: 315 REQQEE-------RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 1642 RDAEEK 1647
++ E +
Sbjct: 368 QEEERR 373
Score = 70.5 bits (171), Expect = 1e-11
Identities = 61/247 (24%), Positives = 127/247 (51%), Gaps = 37/247 (14%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERK-------LGQMRTQSLNPAPFSPLTAQ 1460
E+ +R E + ++E+ L+E++ER+R +++R+ L + R + + P +
Sbjct: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE 897
Query: 1461 QMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1520
Q++ E+ LQ +E + RE + +++ + ER+ + + +EE + R+
Sbjct: 898 QLRKEQ-QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE---------EQLLREE 947
Query: 1521 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDD 1580
+EK +Q++ E Q + D+ ++ + +L+ E ++R QE ++K ++
Sbjct: 948 REKRRRQER------------ERQYRKDKKLQQKEE--QLLGEEPEKRRRQEREKKYREE 993
Query: 1581 EEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRR-QEEER 1639
EE + ++ + R E E+R R E R+ ++ +E+++ E E R+E E+RR QE ER
Sbjct: 994 EELQQEEEQLL----REEREKRRRQEWERQYRKKDELQQEE-EQLLREEREKRRLQERER 1048
Query: 1640 TKRDAEE 1646
R+ EE
Sbjct: 1049 QYREEEE 1055
Score = 70.5 bits (171), Expect = 1e-11
Identities = 61/249 (24%), Positives = 125/249 (50%), Gaps = 24/249 (9%)
Query: 1410 RKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1469
R E+ R E+E+ +E+E++ +R+E +++L Q R + Q+ + ++
Sbjct: 1582 RLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE---DEQLLQEREEQQLHR 1638
Query: 1470 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEE--LSSGDSLSPDPWKRDAKEKLEKQ 1527
+R ++ + E Q ++Q R + R + +EE L G+ +RD K + E+Q
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698
Query: 1528 Q---QMHIVDMLSKEIQELQSKPDRSAEESDRLRK------LMLEWQFQKRLQESKQKDE 1578
Q Q L +E Q + + +R E ++LR+ L + +++K L+E + + E
Sbjct: 1699 QLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPE 1758
Query: 1579 DDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEE 1638
+E++ ++R E +R+ R+EE+ RQ++ E+ + + DR +EEE+ RQE E
Sbjct: 1759 REEQQ----------LRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQERE 1808
Query: 1639 RTKRDAEEK 1647
+ +++
Sbjct: 1809 EQQLRPQQR 1817
Score = 69.7 bits (169), Expect = 2e-11
Identities = 71/270 (26%), Positives = 130/270 (48%), Gaps = 38/270 (14%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERER--KRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1465
ERR+++E +R ++ + + EE RE+ +R ++ER+ Q+R + L +Q +
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372
Query: 1466 KPSTLQRPQ----------ETVIR---ELQPQQQPRTIE--RRDLQYITVSKEELSSGDS 1510
+ L+R Q E +R +L+ +QQ R + RR+ Q + +
Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 1511 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDR-------SAEESDRLRKLMLE 1563
+++ +E+ K++Q D L +E + + + +R EE R R L LE
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLE 492
Query: 1564 WQFQKRLQESKQKDEDDEEEEDDDV------DTMLIMQRLEAERRARDEERRRQQQLEEM 1617
+ ++ QE +++ E+EE + + + QRL +E++ R E+ R++QL
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL--- 549
Query: 1618 RKREAEDRARQEEERRRQEEERTKRDAEEK 1647
KRE E R E+ERR E+R KR+ EE+
Sbjct: 550 LKREEEKRL--EQERR---EQRLKREQEER 574
Score = 68.9 bits (167), Expect = 4e-11
Identities = 58/265 (21%), Positives = 131/265 (49%), Gaps = 42/265 (15%)
Query: 1408 ERRKREEH-----QRWYEKEKARLEEER----------------ERKRRE--QERKLGQM 1444
+R++R+E Q W E+E+ R EEE+ + +RRE + R+ G+
Sbjct: 165 DRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGRE 224
Query: 1445 RTQSLNPAPFSPLTAQQMKPE--KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSK 1502
Q + ++ + E K T+ R +E ++E +PQ+Q R ++ + Q + +
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ-RELQEEEEQLRKLER 283
Query: 1503 EELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLS-KEIQELQSKPDRSAEESDRLRKLM 1561
+EL +R+ +E+ ++QQ++ L K+ +E + + + E+ +R +
Sbjct: 284 QEL-----------RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 1562 LEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRA----RDEERRRQQQLEEM 1617
+ Q R ++ +++++ E++++ + + E ERR R+++ RR+QQL
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRRE 392
Query: 1618 RKREAEDRARQEEERRRQEEERTKR 1642
++ E + R+E++ RR+++ R ++
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQ 417
Score = 68.6 bits (166), Expect = 5e-11
Identities = 65/254 (25%), Positives = 114/254 (44%), Gaps = 50/254 (19%)
Query: 1408 ERRKREEHQRWYEKEKARLEE------ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQ 1461
ER+ REE + E+E+ EE ERER+ RE+E Q R Q Q
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQ 1226
Query: 1462 MKPEKPSTLQRP-------QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPD 1514
+PEK + ++ + R+L+ Q ++DLQ++ ++E
Sbjct: 1227 WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE---------- 1276
Query: 1515 PWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESK 1574
RD +++ + QQ D E ++L+ + + A+ DR + QE K
Sbjct: 1277 ---RDREQERRRWQQR---DRHFPEEEQLEREEQKEAKRRDR------------KSQEEK 1318
Query: 1575 QKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRR 1634
Q ++ EE+ +R E +R+ R+EE+ Q++ E+ +R+ DR +EEE R
Sbjct: 1319 QLLREEREEK---------RRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRH 1369
Query: 1635 QEEERTKRDAEEKV 1648
QE+ R + E+++
Sbjct: 1370 QEQGRKFLEEEQRL 1383
Score = 68.2 bits (165), Expect = 6e-11
Identities = 63/255 (24%), Positives = 127/255 (49%), Gaps = 16/255 (6%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1462
Q E ++EE Q E+ + R +E ER+ R++E +L Q Q L P ++
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEE-ELQQEEEQLLREEPEKRRRQERE 1107
Query: 1463 KP-EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAK 1521
+ + LQ+ +E ++RE + +++ + +ER+ + V +EE L +P KR +
Sbjct: 1108 RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE---EQLLREEPEKR-RR 1163
Query: 1522 EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDE 1581
++LE+Q + ++ +E Q L+ + ++ +E +R + E Q QKR Q + +D+ +
Sbjct: 1164 QELERQYREE-EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSD 1222
Query: 1582 -------EEEDDDVDTMLIMQRLEAE--RRARDEERRRQQQLEEMRKREAEDRARQEEER 1632
E+E+ D + + E E R+ D + R +Q ++++ E + R E+
Sbjct: 1223 LKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQE 1282
Query: 1633 RRQEEERTKRDAEEK 1647
RR+ ++R + EE+
Sbjct: 1283 RRRWQQRDRHFPEEE 1297
Score = 67.8 bits (164), Expect = 8e-11
Identities = 71/262 (27%), Positives = 127/262 (48%), Gaps = 38/262 (14%)
Query: 1409 RRKREEHQRWYE-KEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
RR++EE +R + + + +L E++ +R +Q R+ Q+R + QQ++ E+
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 424
Query: 1468 STLQRPQETVIRELQPQQQPRTI-------ERRDLQYITVSKEELSSGDSLSPDPWKRDA 1520
L+R QE E + +Q+ R ERRD ++ +E KRD
Sbjct: 425 --LRREQEEERHEQKHEQERREQRLKREQEERRD--WLKREEETERHEQERRKQQLKRDQ 480
Query: 1521 KE-------KLE----KQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR 1569
+E KLE ++QQ L +E +E + + + EE +RL++ + Q +R
Sbjct: 481 EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR 540
Query: 1570 LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQE 1629
QE +++ EEE +RLE ERR + +R ++++ +++ KRE E RQ+
Sbjct: 541 EQEERREQLLKREEE----------KRLEQERREQRLKREQEERRDQLLKREEE--RRQQ 588
Query: 1630 EERRRQE---EERTKRDAEEKV 1648
+R QE E+R KR+ E++
Sbjct: 589 RLKREQEERLEQRLKREEVERL 610
Score = 67.8 bits (164), Expect = 8e-11
Identities = 64/276 (23%), Positives = 129/276 (46%), Gaps = 32/276 (11%)
Query: 1400 PSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQE------------RKLGQMRTQ 1447
P Q R+++EE +R E E EEER +++++E + + Q
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782
Query: 1448 SLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIER---RDLQYITVSKEE 1504
L+ P PL Q+ + + Q+ ++ + E + ++Q R R ++LQ++ +E+
Sbjct: 783 RLSARP--PLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLE-EEEQ 839
Query: 1505 L----------SSGDSLSPDPWKRDAKEKLEKQQ-QMHIVDMLSKEIQELQSKP---DRS 1550
L D L D +R ++E+ Q+ + + + + L +KP ++
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 1551 AEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRR 1610
+E L++ E Q ++R + +Q+ E EE+ + R E E+R R E R+
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959
Query: 1611 QQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEE 1646
++ ++++++E + + E+RRRQE E+ R+ EE
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995
Score = 66.6 bits (161), Expect = 2e-10
Identities = 66/248 (26%), Positives = 114/248 (45%), Gaps = 23/248 (9%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQE--RKLGQMRTQSLNPAPFSPLTAQ 1460
Q+ E+++ + R ++EK L EERE KRR QE RK + Q L PL Q
Sbjct: 1298 QLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFRE-EEQLLQEREEQPLRRQ 1356
Query: 1461 QMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDA 1520
+ + R QE + L+ +Q+ R ER + +++L + RD
Sbjct: 1357 ERDRKFREEELRHQEQGRKFLEEEQRLRRQERE--RKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 1521 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDD 1580
K + E+QQ LS+ Q + + EE ++R+ E +F + Q+ +Q+
Sbjct: 1415 KFREEEQQ-------LSR-----QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRK 1462
Query: 1581 EEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERT 1640
EE+ ++Q E ++ R E R+ + E+ +R+ DR +E+E R QE ER
Sbjct: 1463 FREEEQ------LLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516
Query: 1641 KRDAEEKV 1648
+ E+++
Sbjct: 1517 FLEEEQQL 1524
Score = 66.2 bits (160), Expect = 2e-10
Identities = 54/240 (22%), Positives = 117/240 (48%), Gaps = 39/240 (16%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
ER + +E +RW ++++ EEE+ + ++E K ++Q +Q+ E+
Sbjct: 1276 ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE----------EKQLLREER 1325
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1527
+R QET + + +++ + ++ R+ Q P +R +++ ++
Sbjct: 1326 EEKRRRQET---DRKFREEEQLLQEREEQ------------------PLRRQERDRKFRE 1364
Query: 1528 QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDD 1587
+++ + K ++E ++ +R RK + E Q Q R QE +Q+ D + + +
Sbjct: 1365 EELRHQEQGRKFLEE-----EQRLRRQERERKFLKEEQ-QLRCQEREQQLRQDRDRKFRE 1418
Query: 1588 VDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1647
+ L R E +R+ R+EE++ ++Q E + E E + RQE R+ +EEE+ ++ EE+
Sbjct: 1419 EEQQL--SRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
Score = 66.2 bits (160), Expect = 2e-10
Identities = 62/250 (24%), Positives = 119/250 (47%), Gaps = 29/250 (11%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKL----GQMRTQSLNPAPFSPLTAQQMK 1463
+R+ REE R E+ + LEEE+ +R+E+ERK Q+R Q QQ++
Sbjct: 1359 DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE---------QQLR 1409
Query: 1464 PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK 1523
++ + ++ +L Q++ R + Q V ++E +++ K
Sbjct: 1410 QDRDRKFREEEQ----QLSRQERDRKFREEEQQ---VRRQERERKFLEEEQQLRQERHRK 1462
Query: 1524 LEKQQQMHIVDMLSKEIQEL--QSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDE 1581
+++Q+ + +E Q+L Q + + EE +LR+ + +F+++ S++ +
Sbjct: 1463 FREEEQL----LQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
Query: 1582 EEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEER---RRQEEE 1638
EEE + L+ E++ R +ER +Q++ + RK E++ RQE E RQE +
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578
Query: 1639 RTKRDAEEKV 1648
R R E+KV
Sbjct: 1579 RKFRLEEQKV 1588
Score = 65.1 bits (157), Expect = 5e-10
Identities = 67/264 (25%), Positives = 118/264 (44%), Gaps = 57/264 (21%)
Query: 1407 AERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1466
A+ R+ + + R ++E R +E+E KRR +E
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE---------------------------- 743
Query: 1467 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSG-DSLSPDPWKRDAKEK-L 1524
S LQ +E E +QQ +RRD + ++E+ G LS P R+ +E+ L
Sbjct: 744 -SELQWQEE----ERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQL 798
Query: 1525 EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEE 1584
+++ E +E + + + E L+ L E Q Q+R + + ++E+D +E
Sbjct: 799 RAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQE 858
Query: 1585 DDDVDTMLIMQR-------LEAERRAR----------DEERRRQQQL-----EEMRKREA 1622
D + +R LE ER+ R E+ R++QQL EE+++ E
Sbjct: 859 DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREER 918
Query: 1623 EDRARQEEERRRQEEERTKRDAEE 1646
E R RQE+ER+ +EEE+ +++ E+
Sbjct: 919 EKRRRQEQERQYREEEQLQQEEEQ 942
Score = 65.1 bits (157), Expect = 5e-10
Identities = 67/282 (23%), Positives = 134/282 (47%), Gaps = 41/282 (14%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
ER +++ H++ E+++ LEEE++ +R+E++RK + +S P QQ+ ++
Sbjct: 1472 EREEQQLHRQ--ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQR 1529
Query: 1468 STLQRPQETVIRELQPQQQPRTIE----------RRDLQYITVSKEELSSGDSLSPDPWK 1517
+E +R + QQ R R++ + +S++E L +
Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVR 1589
Query: 1518 RDAKEK--LEKQQQMHIVDMLSKEIQE-----------LQSKPDRSAEESDRLRKLMLEW 1564
R +E+ +E +QQ+ + + QE LQ + ++ +R RK LE
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF-LEE 1648
Query: 1565 QFQKRLQESKQKDEDDEEEEDDDVDTMLI------MQRLEAERRARDEER--RRQ----- 1611
+ Q R QE +Q+ D + + + + +L ++R E +R+ R+EE+ RRQ
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Query: 1612 --QQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKVMVL 1651
Q+ +++R++E E + R+EE+ R++ E+ R E +L
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKIL 1750
Score = 64.3 bits (155), Expect = 9e-10
Identities = 60/241 (24%), Positives = 116/241 (48%), Gaps = 29/241 (12%)
Query: 1408 ERRKREEHQRWYEKEKARL--EEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1465
+R+ REE Q+ +E+ R EEE++ +R+E+ERK + Q +Q+ E
Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 1466 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1525
+ QE + L+ +QQ R ER D ++ ++EL S + ++ LE
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQER-DRKF---REQELRS---------QEPERKFLE 1519
Query: 1526 KQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEED 1585
++QQ+H K +QE Q +L + + Q+R Q+ +K ++E+
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQ--------------QLRRQERGQQRRQDRDRKFREEEQLRQ 1565
Query: 1586 DDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
+ + L Q + + R +++ RRQ+Q + + E + R ++ +++ RQE +R R+ E
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDE 1625
Query: 1646 E 1646
+
Sbjct: 1626 Q 1626
Score = 63.9 bits (154), Expect = 1e-09
Identities = 63/257 (24%), Positives = 122/257 (47%), Gaps = 29/257 (11%)
Query: 1408 ERRKREEHQRWYEKEKARLE-EERERKRREQERKL----------GQMRTQSLNPAPFSP 1456
++R+++ +++ E+E+ R E EE++ R+E++RK Q R +
Sbjct: 1547 QQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606
Query: 1457 LTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1516
QQ ++ R E +++E + QQ R + RD +++ +EE
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQLHR--QERDRKFL---EEEPQLRRQEREQQL 1661
Query: 1517 KRDAKEKLEKQQQMHIVDMLSKEIQEL--QSKPDRSAEESDRLRKLMLEWQF-----QKR 1569
+ D K +++Q+ + E Q+L Q + + EE +LR+ E +F Q R
Sbjct: 1662 RHDRDRKFREEEQL----LQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717
Query: 1570 LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQE 1629
QE ++K ++E+ + L +R E R+ +EE+ R ++ E+ +R+ DR +E
Sbjct: 1718 RQELERKFREEEQLRQETEQEQL--RRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Query: 1630 EERRRQEEERTKRDAEE 1646
EE+ RQE E + ++E
Sbjct: 1776 EEQLRQEREEQQLRSQE 1792
Score = 58.9 bits (141), Expect = 4e-08
Identities = 63/255 (24%), Positives = 120/255 (47%), Gaps = 33/255 (12%)
Query: 1408 ERRKREEHQ--RWYEKEKARLEEERERKRREQERKLG------------QMRTQSLNPAP 1453
+R+ REE Q R E+E+ L+EE++ +R+E ERK Q+R Q
Sbjct: 1690 DRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR-- 1747
Query: 1454 FSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1513
L +Q++PE+ R QE R+ + ++Q R ER + Q + + S
Sbjct: 1748 -KILEEEQLRPEREEQQLRRQERD-RKFREEEQLRQ-EREEQQL----RSQESDRKFREE 1800
Query: 1514 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1573
+ +++ +E+ + QQ +E +L+ + R +E DR + ++ Q++ +
Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Query: 1574 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERR 1633
+Q+ +EE++ +R E ER+ R+E RRQQ+ E+ ++ E ++++ +
Sbjct: 1861 EQELWQEEEQK----------RRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHG 1910
Query: 1634 RQEEERTKRDAEEKV 1648
R E T + A V
Sbjct: 1911 RLLEPGTHQFASVPV 1925
Score = 38.9 bits (89), Expect = 0.042
Identities = 28/111 (25%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Query: 128 LKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRP 187
L+ E + + + Q E+QE+E Q +R + K+E+++RE++ R+ ++ +R
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR--EQQERR 328
Query: 188 FQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFR 238
Q E+ +L E ++ E R + RR+Q+ E+R Q+ R
Sbjct: 329 EQQEERREQQLRRE-QEERREQQLRREQEEERREQQLRREQEEERREQQLR 378
Score = 37.0 bits (84), Expect = 0.16
Identities = 19/45 (42%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQ 1447
Q A E+ +REE + W E+E+ R +ERERK RE+ + Q Q
Sbjct: 1850 QFATQEKSRREEQELWQEEEQKR-RQERERKLREEHIRRQQKEEQ 1893
Score = 35.0 bits (79), Expect = 0.60
Identities = 29/131 (22%), Positives = 63/131 (48%), Gaps = 6/131 (4%)
Query: 112 VVQLNWNKDDREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVI----QNFKRTLSKKEKK 167
V Q K+ R+ VL+ E + + ++ Q ++E+E + Q +R ++E++
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 168 EKKKREKEALRQASDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQ 227
+++ R ++ LR+ +++ R Q E+ + E ++ E R + RR+
Sbjct: 297 QQRLRREQQLRRKQEEERRE-QQEERREQQERREQQEERREQQLRRE-QEERREQQLRRE 354
Query: 228 QKLEKRMQEFR 238
Q+ E+R Q+ R
Sbjct: 355 QEEERREQQLR 365
Score = 34.7 bits (78), Expect = 0.79
Identities = 27/134 (20%), Positives = 61/134 (45%), Gaps = 12/134 (8%)
Query: 117 WNKDDREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEA 176
W + DR F + + + K+A+ + QE++ +++ + ++++ ++K RE+E
Sbjct: 1286 WQQRDRH--FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQ 1343
Query: 177 LRQASDKD-------DRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQK 229
L Q ++ DR F+ E++ + + K + E R +K +Q +
Sbjct: 1344 LLQEREEQPLRRQERDRKFREEELRHQE---QGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Query: 230 LEKRMQEFRSSDGR 243
++R Q+ R R
Sbjct: 1401 CQEREQQLRQDRDR 1414
Score = 32.3 bits (72), Expect = 3.9
Identities = 26/119 (21%), Positives = 56/119 (47%), Gaps = 9/119 (7%)
Query: 128 LKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKE----KKEKKKREKEALRQASDK 183
L+ E + + + ++ E+E Q KR ++ K+E+++R++ R+ ++
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Query: 184 DDRPFQGEDVE----NSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFR 238
++ + E+VE R + ++ PE + + E + RRQQ+L + QE R
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE-EQEERRQQQLRREQQERR 655
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 79.3 bits (194), Expect = 3e-14
Identities = 56/248 (22%), Positives = 130/248 (52%), Gaps = 25/248 (10%)
Query: 1408 ERRKREEHQRWYEKEKARLEE---ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1464
E R RE+ + W ++EK + EE ERE+K RE+E MR Q ++M+
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEET---MREQE-----------EKMQK 417
Query: 1465 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQY----ITVSKEELSSGDSLSPDPWKRDA 1520
++ + ++ ++ ++ P+Q+ + E+ +Q I +E++ + + K
Sbjct: 418 QEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Query: 1521 KEKLEKQ--QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDE 1578
+EK+ +Q Q + + + Q++ + +R E+ +RLR+ + QK++ + ++K
Sbjct: 478 QEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 1579 DDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEE 1638
++++ ++ + T +++ E R R+ E++ +++ E M RE E++ +++EE+ R++EE
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM--REQEEKMQEQEEKMREQEE 595
Query: 1639 RTKRDAEE 1646
+ E+
Sbjct: 596 KMWEQEEK 603
Score = 72.8 bits (177), Expect = 3e-12
Identities = 51/252 (20%), Positives = 128/252 (50%), Gaps = 25/252 (9%)
Query: 1408 ERRKREEHQRWYEKEKARLEEE---------RERKRREQERKLGQMRTQSLNPAPFSPLT 1458
E+ + +E + W ++EK R +EE R+ K REQE ++ + + + +
Sbjct: 446 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE--QKMW 503
Query: 1459 AQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1518
Q+ + + R +E +RE + Q R + + K+ + + + R
Sbjct: 504 DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMR 563
Query: 1519 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDE 1578
+ ++K+ ++++M + ++ +++Q + ++ E+ +++ W+ ++++QE ++K
Sbjct: 564 EREKKMREEEEM-----MREQEEKMQEQEEKMREQEEKM------WEQEEKMQEQEEKMW 612
Query: 1579 DDEEE--EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQE 1636
+ EE+ E ++ D M + + E+ + +E+ + +E + RE E++ R++EE+ + +
Sbjct: 613 EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 672
Query: 1637 EERTKRDAEEKV 1648
EE+ R+ EEK+
Sbjct: 673 EEK-MREQEEKM 683
Score = 67.4 bits (163), Expect = 1e-10
Identities = 60/247 (24%), Positives = 121/247 (48%), Gaps = 33/247 (13%)
Query: 1413 EEHQRWYEKEKARLEEERERKRREQERK---LGQMRTQSLNPAPF---SPLTAQQMKPEK 1466
+E R E EK+ ++ + +R+ ER L Q++T +L + L Q+ K K
Sbjct: 193 QEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 252
Query: 1467 PSTLQRPQETVIRELQPQ--QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1524
QE +RE + + +Q + R++ + KE L R+ +E++
Sbjct: 253 QEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 1525 EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE-- 1582
++Q++ + ++ ++++ + ++ + +RL W+ +K+++E +QK D EE
Sbjct: 313 QEQEEK-----MWEQEEKMREQEEKMWRQEERL------WEQEKQMREQEQKMRDQEERM 361
Query: 1583 -EEDDDVDTMLIMQRLEAERRARDEERRRQQQ---LEEMRKREAEDRARQEEERRRQEEE 1638
E+D+ + E E R R++E+ +Q+ EE R RE E + R+EEE R++EE
Sbjct: 362 WEQDE--------RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEE 413
Query: 1639 RTKRDAE 1645
+ ++ E
Sbjct: 414 KMQKQEE 420
Score = 66.6 bits (161), Expect = 2e-10
Identities = 55/253 (21%), Positives = 116/253 (45%), Gaps = 14/253 (5%)
Query: 1399 LPSAQVAAAERR--KREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSP 1456
LP Q + ++EE R EK+ + EE+ R+ + G+MR Q
Sbjct: 224 LPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQE------EK 277
Query: 1457 LTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPW 1516
+ Q+ + + R QE +EL+ Q++ R E + + E+ W
Sbjct: 278 MRRQEKRLREQEKELREQE---KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW 334
Query: 1517 KRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES--- 1573
+++ + +++Q + + + + + +R E+ +R+R+ W+ ++++QE
Sbjct: 335 RQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERI 394
Query: 1574 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERR 1633
+++++ EEE+ + MQ+ E ++E+ +QQ+L E +++ E QE+E +
Sbjct: 395 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 454
Query: 1634 RQEEERTKRDAEE 1646
E+E RD EE
Sbjct: 455 IWEQEEKIRDQEE 467
Score = 64.7 bits (156), Expect = 7e-10
Identities = 55/245 (22%), Positives = 120/245 (48%), Gaps = 37/245 (15%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
E+ + +E + W ++E+ ++ER R++ E+ R+ +M Q ++M+ EK
Sbjct: 493 EKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE-----------EKMREEKK 541
Query: 1468 STLQRP----QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK 1523
+ Q QE +RE + ++ R + + + +E++ + R+ +EK
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM-----REQEEK 596
Query: 1524 LEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEE 1583
+ +Q++ + +++ E + K EE + + W+ ++++QE ++K + EE
Sbjct: 597 MWEQEEK--MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEE- 653
Query: 1584 EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRD 1643
+ E E + R++E + Q Q E+M RE E++ + +EE+ R++EE+ R
Sbjct: 654 -----------KMREQEEKMREQEEKMQGQEEKM--REQEEKMQGQEEKMREQEEK-MRG 699
Query: 1644 AEEKV 1648
EEK+
Sbjct: 700 QEEKM 704
Score = 64.3 bits (155), Expect = 9e-10
Identities = 53/249 (21%), Positives = 122/249 (48%), Gaps = 23/249 (9%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
E + RE+ ++ + +E+ E+E++ REQE+K MR Q + Q + +
Sbjct: 323 EEKMREQEEKMWRQEERLWEQEKQM--REQEQK---MRDQE------ERMWEQDERLREK 371
Query: 1468 STLQRPQETVIRE---LQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1524
R QE + + +Q +++ R E++ + +E+ + W+++ KE
Sbjct: 372 EERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-- 429
Query: 1525 EKQQQMHIVDMLSK--EIQELQSKPDRSAEESDRLRKLMLEWQFQKRL-QESKQKDEDDE 1581
QQ + + K E +++Q + ++ E+ +++R W +K++ ++ K ++++D+
Sbjct: 430 --WQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 487
Query: 1582 EEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMR--KREAEDRARQEEERRRQEEER 1639
E ++ + + E R +++ R +++ E MR K+ + + EE++ QE+E+
Sbjct: 488 MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEK 547
Query: 1640 TKRDAEEKV 1648
D EEK+
Sbjct: 548 KTWDQEEKM 556
Score = 62.4 bits (150), Expect = 4e-09
Identities = 55/254 (21%), Positives = 119/254 (46%), Gaps = 48/254 (18%)
Query: 1408 ERRKREEHQRWYEKEKARLE---EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1464
E R RE+ + W ++EK R E +E+E+K +QE K+ + + ++ K
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEER----------MREREKKM 569
Query: 1465 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1524
+ + R QE ++E +++ R E + + +E+ W+++ ++K+
Sbjct: 570 REEEEMMREQEEKMQE--QEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 1525 EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEE 1584
++Q++M + + ++ E+ +++ W+ +++++E ++K + EE+
Sbjct: 628 QEQEEM------------MWEQEEKMQEQEEKM------WEQEEKMREQEEKMREQEEKM 669
Query: 1585 DDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKRE------AEDRARQEEERRRQEEE 1638
+ M E E + + +E + ++Q E+MR +E E QEE+ QEE
Sbjct: 670 QGQEEKM-----REQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEM 724
Query: 1639 RTK----RDAEEKV 1648
R K RD +EK+
Sbjct: 725 REKEERIRDQKEKM 738
Score = 55.5 bits (132), Expect = 4e-07
Identities = 53/247 (21%), Positives = 115/247 (46%), Gaps = 27/247 (10%)
Query: 1418 WYEKEKARLEE-ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQET 1476
W++K +EE +ER E + + L ++ + S +Q +
Sbjct: 153 WHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE 212
Query: 1477 VIRELQ------PQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQM 1530
+ R+L+ PQ Q T++ + +E+ W+++ E+L +Q+
Sbjct: 213 LKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQE--ERLREQE-- 268
Query: 1531 HIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDT 1590
+ ++ ++++ + R E+ LR+ E + QK+L+E +++ ++ EE+ + +
Sbjct: 269 ---GKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEK 325
Query: 1591 MLIMQRLEAERRARDEER----RRQQQLEEMRKREAEDRARQEEERRRQEEERTKR---- 1642
M R + E+ R EER +Q + +E + R+ E+R +++ER R++EER +
Sbjct: 326 M----REQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKM 381
Query: 1643 -DAEEKV 1648
+ EEK+
Sbjct: 382 WEQEEKM 388
Score = 53.1 bits (126), Expect = 2e-06
Identities = 47/196 (23%), Positives = 92/196 (46%), Gaps = 28/196 (14%)
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1527
ST + + I EL ++ ++E L T++ EEL ++ + + EK E Q
Sbjct: 151 STWHKKADRYIEELTKERDALSLE---LYRNTITNEELKKKNAELQEKLRLAESEKSEIQ 207
Query: 1528 -------QQMHIVDMLSKEIQ------ELQSKPDRSAEESDRLRKLMLE-WQFQKRLQES 1573
+++ L ++Q E+ + + E+ ++RK + W+ ++RL+E
Sbjct: 208 LNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQ 267
Query: 1574 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQ-QLEEMRKREAEDRARQEEER 1632
+ K + EE+ M+R E R +++E R Q+ +L E +K ++ QE+E
Sbjct: 268 EGKMREQEEK----------MRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEE 317
Query: 1633 RRQEEERTKRDAEEKV 1648
+ E+E R+ EEK+
Sbjct: 318 KMWEQEEKMREQEEKM 333
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 77.0 bits (188), Expect = 1e-13
Identities = 114/527 (21%), Positives = 222/527 (42%), Gaps = 75/527 (14%)
Query: 1140 SPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITS 1199
S SPQ+ +YS L + RA R + A +P + G ++ ++ +
Sbjct: 311 SSPSPQVLAQKYS----LVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY--LERLLN 364
Query: 1200 VSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWP-NYEEKPHM 1258
V EQ PP EA P+ A++ + N WP N E +
Sbjct: 365 VEVPQKVGSEQKEPPE-EAEPVA------------AAEPEVPENNGNNSWPHNDTEIANS 411
Query: 1259 HTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSS 1318
+ ++ + + + Q+E + D+A R ++A ++S + S LD
Sbjct: 412 TPNPKPAASSPETPSAGQQEAKTDQA-DGPREPPQSARRKRS----YKQAVSELDE---- 462
Query: 1319 QEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPP--------PPPP 1370
++HL P R KTP++ P V +P+RT L P
Sbjct: 463 EQHLEDEELQ-----------PPRSKTPSS-PCPASKVVRPLRTFLHTVQRNQMLMTPTS 510
Query: 1371 PPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWY--EKEKARLEE 1428
P F + + PL P + + ++ R++ E R E++K R E
Sbjct: 511 APRSVMKSF--IKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLE 568
Query: 1429 ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPR 1488
E + KR E+ RK+ Q R + +QMK EK +++ + + + ++ R
Sbjct: 569 EVKLKREERLRKVLQARER-----------VEQMKEEKKKQIEQKFAQIDEKTEKAKEER 617
Query: 1489 TIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSK-- 1546
E + + K E + +R + E++++ H ++L K+ +E Q +
Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH-QELLQKKKEEEQERLR 676
Query: 1547 ----PDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERR 1602
R AE+ ++ R+ + ++R QE ++++ ++E + + + +RL+AER
Sbjct: 677 KAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERE 736
Query: 1603 ARDEERRRQQQLEEMRKREAEDRARQEEERR---RQEEERTKRDAEE 1646
++ E+ + Q E++ +RE E++ ++EE++R RQ +E ++ A+E
Sbjct: 737 LQEREKALRLQKEQL-QRELEEKKKKEEQQRLAERQLQEEQEKKAKE 782
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 76.6 bits (187), Expect = 2e-13
Identities = 114/525 (21%), Positives = 221/525 (42%), Gaps = 75/525 (14%)
Query: 1140 SPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKITS 1199
S SPQ+ +YS L + RA R + A +P + G ++ ++ +
Sbjct: 311 SSPSPQVLAQKYS----LVAKQESVVRRASRRLAKKTAEEPAASGRIICHSY--LERLLN 364
Query: 1200 VSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQNQWP-NYEEKPHM 1258
V EQ PP EA P+ A++ + N WP N E +
Sbjct: 365 VEVPQKVGSEQKEPPE-EAEPVA------------AAEPEVPENNGNNSWPHNDTEIANS 411
Query: 1259 HTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSS 1318
+ ++ + + + Q+E + D+A R ++A ++S + S LD
Sbjct: 412 TPNPKPAASSPETPSAGQQEAKTDQA-DGPREPPQSARRKRS----YKQAVSELDE---- 462
Query: 1319 QEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPIRTDLPP--------PPPP 1370
++HL P R KTP++ P V +P+RT L P
Sbjct: 463 EQHLEDEELQ-----------PPRSKTPSS-PCPASKVVRPLRTFLHTVQRNQMLMTPTS 510
Query: 1371 PPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEER 1430
P F + L + P Q + AE+ +R++ E++K R EE
Sbjct: 511 APRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQK----VEEDKRRRLEEV 566
Query: 1431 ERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTI 1490
+ KR E+ RK+ Q R + +QMK EK +++ + + + ++ R
Sbjct: 567 KLKREERLRKVLQARER-----------VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 615
Query: 1491 ERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSK---- 1546
E + + K E + +R + E++++ H ++L K+ +E Q +
Sbjct: 616 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH-QELLQKKKEEEQERLRKA 674
Query: 1547 --PDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR 1604
R AE+ ++ R+ + ++R QE ++++ ++E + + + +RL+AER +
Sbjct: 675 AEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQ 734
Query: 1605 DEERRRQQQLEEMRKREAEDRARQEEERR---RQEEERTKRDAEE 1646
+ E+ + Q E++ +RE E++ ++EE++R RQ +E ++ A+E
Sbjct: 735 EREKALRLQKEQL-QRELEEKKKKEEQQRLAERQLQEEQEKKAKE 778
>gi|148612825 Rap GTPase interactor [Homo sapiens]
Length = 1075
Score = 75.5 bits (184), Expect = 4e-13
Identities = 168/798 (21%), Positives = 275/798 (34%), Gaps = 168/798 (21%)
Query: 248 GTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVMLPPGAQ 307
G L+++ DS+ YK++L + T A V EALE+Y L+ Y + V+ G
Sbjct: 63 GVLKVFGDSVCTGTHYKSVLATGTSSARELVKEALERYALDPRQAGQYVLCDVVGQAGDA 122
Query: 308 HSDEKGAKEIILDDDECPLQIFREWPSDKGI-LVFQLKRRPPDHIPKKTKKHLEGKTP-- 364
+ + D E PL I W +G+ F+L++R + + K ++ T
Sbjct: 123 GQRWQARCFRVFGDSEKPLLIQELWKPREGLSRRFELRKR--SDVEELAAKEVDTITAGI 180
Query: 365 ------KGKERADGS-----GYGSTLPPEKLPYLV-------------------ELSPGR 394
+ RA G+ G + PP +L V E P
Sbjct: 181 NAQARRLQRSRAKGTPTPALGDARSSPPPRLRRTVSETSLSPVNALPAAAQGPEEPGPDA 240
Query: 395 RNHFAYYNYH-TYEDGSDSRDKPKLYRLQLSVTEVGTEKLDDN-SIQLFGPGIQPHHCDL 452
+ Y + H G + +Y L VG SI L P I P HC +
Sbjct: 241 MRYSLYQSPHLLLLQGYSQQHDSLVYVLNRDRHTVGQRTPSSKPSISLSAPDILPLHCTI 300
Query: 453 TNMDGVVTVTPRSMDAETYVEGQRIS--------ETTMLQSGMKVQFGASHVFKFVDPSQ 504
+ + G IS T +L G + G ++ F DP+Q
Sbjct: 301 RRQPLPDSGQAAGRLVLEPIPGAHISVNFSEVGHRTVVLHHGDLLSLGLYYLLLFKDPAQ 360
Query: 505 DHALAKRSVDGGLMVKGPRHKPGIVQETTFDLGGDIHSGTALPTSKSTTRLDSDRVSSAS 564
L R++ L + RL +
Sbjct: 361 AQPLPARAL------------------------------ARLRAVPQSCRL------CGA 384
Query: 565 STAERGMVKPMIRVEQQPDYRRQESRTQDASGPELILPASIEFRESSEDSFLSAIINYTN 624
+ RG P Q RRQ +L+L EF ED+ L I+
Sbjct: 385 ALGARGAASP----TQAALPRRQ----------QLLL----EFEPHLEDTLLQRIMTLIE 426
Query: 625 SSTVHFKLSPTYVLYMACRYVLSNQYRPD------ISPTERTHKVIAVVNKMVSMMEGVI 678
KL+P ++L + C + ++P + + + K ++ + +
Sbjct: 427 PGGDDHKLTPAFLLCL-CIQHSATHFQPGTFGQLLLKIARLIRETVWEKTKELAEKQAQL 485
Query: 679 QKQKNIAGA-----------LAFWMANASELLNFIKQ------------------DRDLS 709
Q+ ++A + FWM+N+ ELL FI+Q L
Sbjct: 486 QEPISLASCAMADLVPDLQPILFWMSNSIELLYFIQQKCPLYMQSMEEQLDITGSKESLF 545
Query: 710 RITLDAQD----VLAHLVQMAFKYLVHCLQSELNNYMPAFLDDP------EENSLQRPKI 759
TL A + VL +V AF+ V+ + L +PA L+ P E+ P++
Sbjct: 546 SCTLTASEEAMAVLEEVVLYAFQQCVYYVSKSLYICLPALLECPPFQTERRESWSSAPEL 605
Query: 760 DD----VLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHY- 814
+ V+ A+ LLR+ +V+ + Q+ + LF F L N+L+ S C H+
Sbjct: 606 PEELRRVVSVYQAALDLLRQLQVHPEVASQMLAYLFFFSGTLLLNQLLDRGPSLSCFHWP 665
Query: 815 WGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMDKYAPDDIPNINSTCFK-- 872
G +L + W G A + ++ LL + + ++ T +
Sbjct: 666 RGVQACARLQQLLEWMRSAGFGAAGEHFFQKLSCTLNLLATPR---AQLIQMSWTALRAA 722
Query: 873 ---LNSLQLQALLQNYHCAPDEPFIPTDLIENVVTVAENTADELARSDGREVQLEEDPDL 929
L+ QL LL +Y A P E + E RS+ E P
Sbjct: 723 FPALSPAQLHRLLTHYQLA--SAMGPMSTWE----PGAQDSPEAFRSEDVLESYENPP-- 774
Query: 930 QLPFLLPEDGYSCDVVRN 947
P +LP DG+ D+ N
Sbjct: 775 --PIVLPSDGFQVDLEAN 790
Score = 53.5 bits (127), Expect = 2e-06
Identities = 28/86 (32%), Positives = 50/86 (58%), Gaps = 1/86 (1%)
Query: 1007 IITVTLKK-QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRS 1065
+ TV L++ +G+G+ ++ G+Y+++++ G A DGRL+ GD++L V+G S
Sbjct: 974 VFTVELERGPSGLGMGLIDGMHTHLGAPGLYIQTLLPGSPAAADGRLSLGDRILEVNGSS 1033
Query: 1066 LVGLSQERAAELMTRTSSVVTLEVAK 1091
L+GL RA +L+ + VAK
Sbjct: 1034 LLGLGYLRAVDLIRHGGKKMRFLVAK 1059
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 74.3 bits (181), Expect = 9e-13
Identities = 60/253 (23%), Positives = 134/253 (52%), Gaps = 34/253 (13%)
Query: 1408 ERRKREEHQRWYEKEKARLEEE----RERKRREQERKLGQ---MRTQSLNPAPFSPLTAQ 1460
E+ +R+E W ++EK R +EE +E K RE E K+ + +R Q + Q
Sbjct: 363 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 1461 QMKPEKPSTLQRPQETVIRELQPQ--QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1518
+ + E+ + + R QE IRE + + +Q + + R++ E++ + + + ++
Sbjct: 423 EKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQE--------EKIHEQEKIREEEKRQ 473
Query: 1519 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRLQESKQKD 1577
+ +E +++++H E +E+ + ++ E+ +++RK + W+ +++++E ++K
Sbjct: 474 EQEEMWRQEEKIH-------EQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI 526
Query: 1578 EDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQ--LEEMRKREAEDRARQEEERRRQ 1635
+ EE+ + + E E R+EE+ +Q+ EE +++E ED+ ++EE+ R+
Sbjct: 527 REQEEKMWRQEEKI-----REQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
Query: 1636 EEERTKRDAEEKV 1648
+EE+ R EEK+
Sbjct: 582 QEEKVWRQ-EEKI 593
Score = 66.2 bits (160), Expect = 2e-10
Identities = 58/247 (23%), Positives = 127/247 (51%), Gaps = 25/247 (10%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
E+ +++E + W ++EK R E+E K REQE K+ + + +Q + +
Sbjct: 503 EKIRKQEEKVWRQEEKIR---EQEEKIREQEEKMWRQEEK----------IREQEEMWRE 549
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-DAKEKLEK 1526
QE + E + Q+Q + R++ + ++ + + KR + +EK+ K
Sbjct: 550 EEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWK 609
Query: 1527 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1586
Q++ + ++IQE + K R EE R ++ M + Q ++++ E ++K + EE+ +
Sbjct: 610 QEEK--IREQEEKIQEQEEKI-REQEEKIREQEEMTQEQ-EEKMGEQEEKMCEQEEKMQE 665
Query: 1587 DVDTMLIMQRL--EAERRARDEERRRQQQLEEMRKREA-----EDRARQEEERRRQEEER 1639
+TM + E E++ R++E + ++Q E M+++E E++ ++EE+ +++EE+
Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 725
Query: 1640 TKRDAEE 1646
+R E+
Sbjct: 726 MRRQEEK 732
Score = 64.3 bits (155), Expect = 9e-10
Identities = 53/251 (21%), Positives = 125/251 (49%), Gaps = 23/251 (9%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRRE----QERKLGQMRTQSLNPAPFSPLTAQQMK 1463
E + E+ + W +KEK +EE+ RK+ E QE K+ + + + Q+ K
Sbjct: 482 EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEK---------IREQEEK 532
Query: 1464 PEKPSTLQRPQETVIRELQPQQQPRTI---ERRDLQYITVSKEELSSGDSLSPDPWKRDA 1520
+ R QE + RE + + I E+R Q + ++E + W+++
Sbjct: 533 MWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQ-EEKVWRQEE 591
Query: 1521 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL-QESKQKDED 1579
K + +++++ + + K+ ++++ + ++ E+ +++R+ + + Q+ + QE ++K +
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651
Query: 1580 DEEEEDDDVDTMLIMQRL--EAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEE 1637
EE+ + + M + E + R++E++ ++Q E++R++E QE+E + E+
Sbjct: 652 QEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQE---EMMQEQEEKMWEQ 708
Query: 1638 ERTKRDAEEKV 1648
E + EEK+
Sbjct: 709 EEKMCEQEEKM 719
Score = 63.9 bits (154), Expect = 1e-09
Identities = 51/261 (19%), Positives = 128/261 (49%), Gaps = 33/261 (12%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1462
++ E+R+ +E + W ++EK R E+E K REQE+K+ + + +Q
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKIR---EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 474
Query: 1463 KPE--KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDP----W 1516
+ E + QE + R+ + + R+ + + +E++ + + W
Sbjct: 475 QEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMW 534
Query: 1517 KRDAK-----EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRL 1570
+++ K E ++++MH + + +E ++ Q + D+ + +++R+ + W+ ++++
Sbjct: 535 RQEEKIREQEEMWREEEKMHEQEKIWEE-EKRQEQEDKMWRQEEKIREQEEKVWRQEEKI 593
Query: 1571 QESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRK-----REAEDR 1625
+E ++K ++ EE+ + E + R++E + Q+Q E++R+ RE E+
Sbjct: 594 REQEEKRQEQEEK------------MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEM 641
Query: 1626 ARQEEERRRQEEERTKRDAEE 1646
+++EE+ ++EE+ E+
Sbjct: 642 TQEQEEKMGEQEEKMCEQEEK 662
Score = 63.2 bits (152), Expect = 2e-09
Identities = 48/237 (20%), Positives = 120/237 (50%), Gaps = 32/237 (13%)
Query: 1408 ERRKREEHQRWYEKEKARLEEE--RERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPE 1465
E + RE+ + W E+EK +E+ E KR+EQE K+ + ++ E
Sbjct: 537 EEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQ---------------EEKIRE 581
Query: 1466 KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLE 1525
+ + R +E + + + +Q+ + + I +E++ + R+ +EK+
Sbjct: 582 QEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI-----REQEEKIR 636
Query: 1526 KQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLM-LEWQFQKRLQESKQKDEDDEEEE 1584
+Q++M ++ +++ + ++ E+ +++++ W+ +++++E ++K + EE+
Sbjct: 637 EQEEM-----TQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 1585 DDDVDTMLIMQRL--EAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEER 1639
+ + M + E E + ++E + Q+Q E+MR++E ++ ++E R RQ+EE+
Sbjct: 692 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE--EKMWEQEVRLRQQEEK 746
Score = 62.8 bits (151), Expect = 3e-09
Identities = 58/244 (23%), Positives = 124/244 (50%), Gaps = 40/244 (16%)
Query: 1410 RKREEHQRWYEKEKARLEE--ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
R+ E+ Q W EK + + E+ E+E K REQE K MR Q ++M EK
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK---MRRQ------------EEMMWEKE 348
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1527
++R +E + + + RR + + +E++ + + W+++ K + E +
Sbjct: 349 EKMRRQEEMMWEKEEKM-------RRQEEMMWEKEEKMRRQEEMM---WEKEEKIR-ELE 397
Query: 1528 QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDD 1587
++MH + + +E +E + + ++ E+ R + W+ +++++E ++K + E++
Sbjct: 398 EKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK---- 452
Query: 1588 VDTMLIMQRLEAERRARDEERRRQQQ---LEEMRKREAEDRARQEEERRRQEEERTKRDA 1644
+++ + + R+EE+R++Q+ +E + E E+ RQ+E+ QEE+ K+
Sbjct: 453 --MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQ-- 508
Query: 1645 EEKV 1648
EEKV
Sbjct: 509 EEKV 512
Score = 61.6 bits (148), Expect = 6e-09
Identities = 57/257 (22%), Positives = 128/257 (49%), Gaps = 40/257 (15%)
Query: 1394 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAP 1453
A+ +G V+A + + EE++ W RL +++E K QE K+ +
Sbjct: 267 ADHLGKELQSVSAKLQAQVEENELWN-----RLNQQQEEKMWRQEEKIQEW--------- 312
Query: 1454 FSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1513
+ K ++ R QE IRE + + RR + + +E++ + +
Sbjct: 313 -------EEKIQEQEEKIREQEEKIREQEEKM------RRQEEMMWEKEEKMRRQEEMM- 358
Query: 1514 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1573
W+++ EK+ +Q++M M KE ++++ + + E+ +++R+L + Q++++E
Sbjct: 359 --WEKE--EKMRRQEEM----MWEKE-EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ 409
Query: 1574 KQKDEDDEE--EEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEE 1631
++K +++E+ E++ + M R E + R ++E+ R Q++ ++ + ++ + EE
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREE 469
Query: 1632 RRRQEEERTKRDAEEKV 1648
+RQE+E R EEK+
Sbjct: 470 EKRQEQEEMWRQ-EEKI 485
Score = 53.1 bits (126), Expect = 2e-06
Identities = 53/217 (24%), Positives = 100/217 (46%), Gaps = 38/217 (17%)
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK---------- 1517
+T ++ + I EL ++ ++E L T++ EEL ++ + +
Sbjct: 185 ATQKKKADRYIEELTKERDALSLE---LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 241
Query: 1518 ---RDAKEKLEK------QQQMHI-VDMLSKEIQELQSKPDRSAEESDRLRKLMLE---- 1563
++ K KLE+ QQQ+ D L KE+Q + +K EE++ +L +
Sbjct: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 301
Query: 1564 -WQFQKRLQESKQKDEDDEE---EEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRK 1619
W+ ++++QE ++K ++ EE E+++ + R + E EE+ R+Q EEM
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ--EEMMW 359
Query: 1620 REAEDRARQEE-----ERRRQEEERTKRDAEEKVMVL 1651
+ E RQEE E + + +E + EEK+ L
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 396
Score = 45.8 bits (107), Expect = 3e-04
Identities = 53/249 (21%), Positives = 112/249 (44%), Gaps = 38/249 (15%)
Query: 1411 KREEHQRWYEKEKARLE-EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1469
K +E + E EK+ ++ +E KR+ + KL L QQ +
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKL---------------LLPQQQLQAEADH 269
Query: 1470 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1529
L + ++V +LQ Q + + R + +EE W+ +E+ EK ++
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 1530 MHIVDMLSKEIQELQSKPDRSAEESDRLRKLM-LEWQFQKRLQ---------ESKQKDED 1579
+ + ++ ++++ + + E+ +++R+ + W+ +++++ E K + ++
Sbjct: 326 QE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 383
Query: 1580 DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEER 1639
+ E ++ L + E E+ EE+R+ EE + RE E R QE + RQEE+
Sbjct: 384 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQ----EEEKIREQEKRQEQEAKMWRQEEK- 438
Query: 1640 TKRDAEEKV 1648
R+ EEK+
Sbjct: 439 -IREQEEKI 446
Score = 42.4 bits (98), Expect = 0.004
Identities = 45/237 (18%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Query: 1420 EKEKARLEEERERKRREQERKLGQMR------TQSLNPAPFSPLTAQQMKPEKPSTLQRP 1473
E E+ + +E RRE E ++ +R T+ +S +Q++ E + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1474 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-----DAKEKLEKQQ 1528
++ + +Q + + + +E D+LS + ++ + KEK K Q
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 1529 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDV 1588
+ + ++ E E+Q + +R + L+ + Q Q ++ + + V
Sbjct: 228 EK--LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1589 DTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
+ + RL ++ + + + Q E + +E E++ R++EE+ R++EE+ +R E
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 73.2 bits (178), Expect = 2e-12
Identities = 57/213 (26%), Positives = 102/213 (47%), Gaps = 25/213 (11%)
Query: 1453 PFSPL---TAQQMKPEKPSTLQRPQE-TVIRELQPQQQPRTIERRDLQYITVSKEELSSG 1508
P SP+ TA + P+ P T + P + ++ P + + +R + +KE +
Sbjct: 288 PSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGTL 347
Query: 1509 DSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQS-----------KPDRSAEESDRL 1557
+ P +A EK H+VD + E + KP ++
Sbjct: 348 AQQAAGPQGEEALEK-------HVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEA 400
Query: 1558 RKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEM 1617
K++ E + Q RLQ+ +++ E E+EE D ++ + ++ E ER +EE R+Q EE
Sbjct: 401 AKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQ---EEE 457
Query: 1618 RKREAEDRARQEEERRRQEEERTKRDAEEKVMV 1650
RKR+ E++ +QE E +R+ E KR AEE++++
Sbjct: 458 RKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLL 490
Score = 50.1 bits (118), Expect = 2e-05
Identities = 57/223 (25%), Positives = 96/223 (43%), Gaps = 52/223 (23%)
Query: 1451 PAPFSP-------LTAQQM---KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1500
P P SP L+ Q M K EK + + + T+ ++ Q +E+ +
Sbjct: 311 PYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHAS 370
Query: 1501 SKEELSSGDSLS-------PDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEE 1553
K ++G P DA E + + L KE QE Q + ++ EE
Sbjct: 371 EKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKE-QEEQERVEK--EE 427
Query: 1554 SDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQ 1613
DRL + +E K+K E++ RLE E R ++EER+RQ+
Sbjct: 428 QDRLER-----------EELKRKAEEER-------------LRLEEEARKQEEERKRQE- 462
Query: 1614 LEEMRKREAEDRARQEEERRRQEE------ERTKRDAEEKVMV 1650
EE +K+E E++ + EE +R+ E E+ +++ +EK M+
Sbjct: 463 -EEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMI 504
Score = 41.2 bits (95), Expect = 0.008
Identities = 36/155 (23%), Positives = 71/155 (45%), Gaps = 15/155 (9%)
Query: 1405 AAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1464
A ER + EE R E+E+ R EEE++++ E++RK G+ + +Q K
Sbjct: 440 AEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQ 499
Query: 1465 EKPSTLQRPQ--ETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1522
EK ++ + ET RE+ Q + +ER + + + +E L K+ E
Sbjct: 500 EKAMIEKQKEAAETKAREVAEQMR---LEREQIM-LQIEQERLER---------KKRIDE 546
Query: 1523 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRL 1557
+++ ++ + + KE ++ +P E+ +L
Sbjct: 547 IMKRTRKSDVPPQVKKEDPKVGVQPAVCVEKKTKL 581
Score = 38.5 bits (88), Expect = 0.054
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 7/75 (9%)
Query: 1572 ESKQKDEDDEEEEDDDVDTMLIMQRLEAERRAR----DEERRRQQQLEEMRKREAEDRAR 1627
+ +Q+ + EE + Q LE ++RAR + R ++LEE R+RE + RA
Sbjct: 52 DERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAA 111
Query: 1628 QEEERR---RQEEER 1639
EE+R+ R+EEER
Sbjct: 112 VEEKRKQKLREEEER 126
Score = 36.6 bits (83), Expect = 0.21
Identities = 31/125 (24%), Positives = 58/125 (46%), Gaps = 28/125 (22%)
Query: 1517 KRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK 1576
K D +++L K+++ L+ Q++ K R+ Q++K+++E +K
Sbjct: 50 KSDERQRLAKERREEREKCLAAREQQILEKQKRA------------RLQYEKQMEERWRK 97
Query: 1577 DEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQE 1636
E+ + ED ++RA EE+R+Q+ EE + EA R+ ER +Q
Sbjct: 98 LEEQRQRED--------------QKRAAVEEKRKQKLREEEERLEA--MMRRSLERTQQL 141
Query: 1637 EERTK 1641
E + K
Sbjct: 142 ELKKK 146
Score = 36.2 bits (82), Expect = 0.27
Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 1595 QRLEAERRARDEE--RRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKVMV 1650
QRL ERR E+ R+QQ+ E +KR +Q EER R+ EE+ +R+ +++ V
Sbjct: 55 QRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAV 112
Score = 34.7 bits (78), Expect = 0.79
Identities = 16/40 (40%), Positives = 29/40 (72%)
Query: 1410 RKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSL 1449
RK EE ++ ++++A +EE+R++K RE+E +L M +SL
Sbjct: 96 RKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSL 135
Score = 34.7 bits (78), Expect = 0.79
Identities = 37/152 (24%), Positives = 65/152 (42%), Gaps = 24/152 (15%)
Query: 114 QLNWNKDDREGRFVLKNENDAIPPKKAQSNGPEKQ---EKEGVIQNFKRTLSKKEKKEKK 170
Q K+ E V K E D + ++ + E++ E+E Q +R K++++EKK
Sbjct: 410 QARLQKEQEEQERVEKEEQDRLEREELKRKAEEERLRLEEEARKQEEER---KRQEEEKK 466
Query: 171 KREKEALRQASDKDDRPFQ--------GEDVENSRLAAEVYKDMPETSFTRTIS----NP 218
K+E E R+A ++ R + E + + E K+ ET
Sbjct: 467 KQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLER 526
Query: 219 EVVMKRRRQQKLEKR------MQEFRSSDGRP 244
E +M + Q++LE++ M+ R SD P
Sbjct: 527 EQIMLQIEQERLERKKRIDEIMKRTRKSDVPP 558
Score = 33.9 bits (76), Expect = 1.3
Identities = 42/201 (20%), Positives = 84/201 (41%), Gaps = 38/201 (18%)
Query: 1392 PSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNP 1451
P+A A AE+R++ Q+ E+++ +EE++R RE+ ++ +
Sbjct: 390 PTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKEEQDRLEREELKRKAE-------- 441
Query: 1452 APFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSL 1511
++++ E+ + Q + E + +Q+ +E+ +G+
Sbjct: 442 -------EERLRLEEEARKQEEERKRQEEEKKKQE--------------GEEKRKAGEEA 480
Query: 1512 SPDPWKRDAKEKL---EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQF-Q 1567
KR A+E+L EKQ+Q + ++ +E R E RL + + Q Q
Sbjct: 481 -----KRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQ 535
Query: 1568 KRLQESKQKDEDDEEEEDDDV 1588
+RL+ K+ DE + DV
Sbjct: 536 ERLERKKRIDEIMKRTRKSDV 556
Score = 31.6 bits (70), Expect = 6.7
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 23/107 (21%)
Query: 1536 LSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQ 1595
L+KE +E + K + E+ +LE Q + RLQ KQ +E +
Sbjct: 57 LAKERREEREKCLAAREQQ------ILEKQKRARLQYEKQMEER--------------WR 96
Query: 1596 RLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKR 1642
+LE +R+ D++R +EE RK++ + + E R+ ERT++
Sbjct: 97 KLEEQRQREDQKRAA---VEEKRKQKLREEEERLEAMMRRSLERTQQ 140
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 72.0 bits (175), Expect = 4e-12
Identities = 62/271 (22%), Positives = 136/271 (50%), Gaps = 42/271 (15%)
Query: 1408 ERRKREEHQRWYEKEKARLEEE----RERKRREQERKLGQ---MRTQSLNPAPFSPLTAQ 1460
E+ +R+E W ++EK R +EE +E K RE E K+ + +R Q + Q
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 1461 QMKPEKPSTLQRPQETV------IRE-----------LQPQQQPRTIERRDLQYITVSKE 1503
+ + E+ + + R +E + IRE + Q++ R E+R Q +E
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 1504 ELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE 1563
E + W++ KEK+ +Q++ + K+ +++ + ++ ++ +++R+ +
Sbjct: 530 EKIREQE---EIWRQ--KEKIHEQEEK-----IRKQEEKMWRQEEKMHDQEEKIREQEEK 579
Query: 1564 -WQFQKRLQESKQKDEDDEEE--EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRK- 1619
W+ +++++E ++K + EE+ E +++ + E E + ++E + Q+Q E+MR+
Sbjct: 580 VWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQ 639
Query: 1620 ----REAEDRARQEEERRRQEEERTKRDAEE 1646
RE E + R++EE+ R++EE + E+
Sbjct: 640 EEKIREQEKKIREQEEKIREQEEMMQEQEEK 670
Score = 63.9 bits (154), Expect = 1e-09
Identities = 54/250 (21%), Positives = 129/250 (51%), Gaps = 22/250 (8%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1462
++ E+R+ +E + W ++EK R E+E K REQE K+ + + ++
Sbjct: 465 KIREQEKRQEQEAKMWRQEEKIR---EQEEKIREQEEKMWRQEEKIHEQEKIR----EEE 517
Query: 1463 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKE 1522
K ++ + R +E + + + +Q I ++ + I +E++ + D +E
Sbjct: 518 KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE-EKIRKQEEKMWRQEEKM-----HDQEE 571
Query: 1523 KLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEE 1582
K+ +Q++ V ++I+E + K R EE R ++ M + Q +K ++ ++ E +E+
Sbjct: 572 KIREQEEK--VWRQEEKIREQEEKI-REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Query: 1583 EEDDDVDTMLIMQRL-EAERRARDEERRRQQQLEEMRKREA-----EDRARQEEERRRQE 1636
++ + +++ E E++ R++E + ++Q E M+++E E++ ++EE+ +++
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688
Query: 1637 EERTKRDAEE 1646
EE+ +R E+
Sbjct: 689 EEKMRRQEEK 698
Score = 63.2 bits (152), Expect = 2e-09
Identities = 63/266 (23%), Positives = 124/266 (46%), Gaps = 45/266 (16%)
Query: 1410 RKREEHQRWYEKEKARLEE--ERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
R+ E+ Q W EK + + E+ E+E K REQE K MR Q ++M EK
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEK---MRRQ------------EEMMWEKE 409
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1527
++R +E + + + ++ + + I +E++ + + KR +EK+ +Q
Sbjct: 410 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 469
Query: 1528 Q-----------QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE---------WQFQ 1567
+ Q + ++I+E + K R E+ K+ E W+ +
Sbjct: 470 EKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 1568 KRLQES----KQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQ---LEEMRKR 1620
++++E +QK++ E+EE M R E + ++E+ R Q++ +E + R
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEK-MWRQEEKMHDQEEKIREQEEKVWRQEEKIR 588
Query: 1621 EAEDRARQEEERRRQEEERTKRDAEE 1646
E E++ R++EE+ R++EE T+ E+
Sbjct: 589 EQEEKIREQEEKIREQEEMTQEQEEK 614
Score = 61.6 bits (148), Expect = 6e-09
Identities = 56/258 (21%), Positives = 128/258 (49%), Gaps = 29/258 (11%)
Query: 1394 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAP 1453
A+ +G V+A + + EE++ W RL +++E K QE K+ + +
Sbjct: 328 ADHLGKELQSVSAKLQAQVEENELWN-----RLNQQQEEKMWRQEEKIQEWEEKIQEQE- 381
Query: 1454 FSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1513
+ Q+ K + R QE ++ E + + RR + + +E++ + +
Sbjct: 382 -EKIREQEEKIREQEEKMRRQEEMMWEKEEKM------RRQEEMMWEKEEKMRRQEEMM- 433
Query: 1514 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1573
W+++ K + E +++MH + + +E +E + + ++ E+ R + W+ +++++E
Sbjct: 434 --WEKEEKIR-ELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Query: 1574 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQ---LEEMRKREAEDRARQEE 1630
++K + EE+ +++ + + R+EE+R++Q+ +E + RE E+ RQ+E
Sbjct: 490 EEKIREQEEK------MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Query: 1631 ERRRQEEERTKRDAEEKV 1648
+ QEE+ K+ EEK+
Sbjct: 544 KIHEQEEKIRKQ--EEKM 559
Score = 58.9 bits (141), Expect = 4e-08
Identities = 53/260 (20%), Positives = 125/260 (48%), Gaps = 15/260 (5%)
Query: 1399 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1458
LP Q+ A +E Q K +A++EE R Q+++ R + +
Sbjct: 319 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ 378
Query: 1459 AQQMK-PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1517
Q+ K E+ ++ +E + R+ + + RR + + +E++ + + W+
Sbjct: 379 EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMM---WE 435
Query: 1518 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
++ K + E +++MH + + +E +E + + ++ E+ R + W+ +++++E ++K
Sbjct: 436 KEEKIR-ELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 1578 EDDEEEEDDDVDTMLIMQRLEAERRARDEER--RRQQQLEEMRK--REAEDRARQEEERR 1633
+ EE+ + + +++ E + +++E R+++++ E + R+ E QEE+ R
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIR 553
Query: 1634 RQEE-----ERTKRDAEEKV 1648
+QEE E D EEK+
Sbjct: 554 KQEEKMWRQEEKMHDQEEKI 573
Score = 52.0 bits (123), Expect = 5e-06
Identities = 47/211 (22%), Positives = 100/211 (47%), Gaps = 40/211 (18%)
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK---------- 1517
+T ++ + I EL ++ ++E L T++ EEL ++ + +
Sbjct: 246 ATQKKKADRYIEELTKERDALSLE---LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 302
Query: 1518 ---RDAKEKLEK------QQQMHI-VDMLSKEIQELQSKPDRSAEESDRLRKLMLE---- 1563
++ K KLE+ QQQ+ D L KE+Q + +K EE++ +L +
Sbjct: 303 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 362
Query: 1564 -WQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQL--EEMRKR 1620
W+ ++++QE ++K ++ EE+ ++ E + R ++E+ RRQ+++ E+ K
Sbjct: 363 MWRQEEKIQEWEEKIQEQEEK----------IREQEEKIREQEEKMRRQEEMMWEKEEKM 412
Query: 1621 EAEDRARQEEERRRQEEERTKRDAEEKVMVL 1651
++ E+E + + +E + EEK+ L
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEKEEKIREL 443
Score = 42.4 bits (98), Expect = 0.004
Identities = 45/237 (18%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Query: 1420 EKEKARLEEERERKRREQERKLGQMR------TQSLNPAPFSPLTAQQMKPEKPSTLQRP 1473
E E+ + +E RRE E ++ +R T+ +S +Q++ E + R
Sbjct: 169 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 228
Query: 1474 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-----DAKEKLEKQQ 1528
++ + +Q + + + +E D+LS + ++ + KEK K Q
Sbjct: 229 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 288
Query: 1529 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDV 1588
+ + ++ E E+Q + +R + L+ + Q Q ++ + + V
Sbjct: 289 EK--LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 346
Query: 1589 DTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
+ + RL ++ + + + Q E + +E E++ R++EE+ R++EE+ +R E
Sbjct: 347 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 403
>gi|148746189 multiple PDZ domain protein [Homo sapiens]
Length = 2041
Score = 72.0 bits (175), Expect = 4e-12
Identities = 44/121 (36%), Positives = 67/121 (55%), Gaps = 9/121 (7%)
Query: 970 HTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKK-QNGMGLSIVAAKGA 1028
H + P + ++ F G S + Q P+ ++TL++ +G+G SIV G+
Sbjct: 1927 HQQEPASSSLSFTGLTSSS--------IFQDDLGPPQCKSITLERGPDGLGFSIVGGYGS 1978
Query: 1029 GQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLE 1088
L IYVK+V GAA DGRL GDQ+++V+G+SL G++ E A ++ RT VTL
Sbjct: 1979 PHGDLPIYVKTVFAKGAASEDGRLKRGDQIIAVNGQSLEGVTHEEAVAILKRTKGTVTLM 2038
Query: 1089 V 1089
V
Sbjct: 2039 V 2039
Score = 64.7 bits (156), Expect = 7e-10
Identities = 37/94 (39%), Positives = 54/94 (57%), Gaps = 4/94 (4%)
Query: 1003 KEPEIITVTLKKQNGMGLSIVAAKGAGQDKL---GIYVKSVVKGGAADVDGRLAAGDQLL 1059
+E E V L K N GL I A G KL GI+VKS+ K A + DGR+ GDQ++
Sbjct: 371 EESETFDVELTK-NVQGLGITIAGYIGDKKLEPSGIFVKSITKSSAVEHDGRIQIGDQII 429
Query: 1060 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQG 1093
+VDG +L G + ++A E++ T V L + ++G
Sbjct: 430 AVDGTNLQGFTNQQAVEVLRHTGQTVLLTLMRRG 463
Score = 59.3 bits (142), Expect = 3e-08
Identities = 34/81 (41%), Positives = 50/81 (61%), Gaps = 9/81 (11%)
Query: 1003 KEPEI---ITVTLKKQ--NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQ 1057
KE E+ +T+ L+K+ G+GLSIV + + G++V +VKGG AD DGRL GDQ
Sbjct: 1716 KEEEVCDTLTIELQKKPGKGLGLSIVGKR----NDTGVFVSDIVKGGIADADGRLMQGDQ 1771
Query: 1058 LLSVDGRSLVGLSQERAAELM 1078
+L V+G + +QE A L+
Sbjct: 1772 ILMVNGEDVRNATQEAVAALL 1792
Score = 54.3 bits (129), Expect = 1e-06
Identities = 28/80 (35%), Positives = 47/80 (58%), Gaps = 6/80 (7%)
Query: 1016 NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAA 1075
+G+G I+ K G + VK+++ GG AD GRL +GD +L + L G+S E+ A
Sbjct: 265 SGLGFGIIGGKATG-----VIVKTILPGGVADQHGRLCSGDHILKIGDTDLAGMSSEQVA 319
Query: 1076 ELMTRTSSVVTLEVAKQGAI 1095
+++ + + V L +A+ GAI
Sbjct: 320 QVLRQCGNRVKLMIAR-GAI 338
Score = 52.0 bits (123), Expect = 5e-06
Identities = 50/188 (26%), Positives = 81/188 (43%), Gaps = 35/188 (18%)
Query: 982 EGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAG------QDKLGI 1035
EG ES L +NT + +P + + + +G+SIV +G G + GI
Sbjct: 1130 EGEGEESEL--QNTAYSN--WNQPRRVELWREPSKSLGISIVGGRGMGSRLSNGEVMRGI 1185
Query: 1036 YVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI 1095
++K V++ A +G L GD+++ VDG L S E+A E + + + V V
Sbjct: 1186 FIKHVLEDSPAGKNGTLKPGDRIVEVDGMDLRDASHEQAVEAIRKAGNPVVFMV------ 1239
Query: 1096 YHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSTQNGSPESPQL-----PWAE 1150
+++N+P R S P + YN S+ N +S Q+ P
Sbjct: 1240 ----QSIINRP----------RKSPLPSLLHNLYPKYNFSSTNPFADSLQINADKAPSQS 1285
Query: 1151 YSEPKKLP 1158
SEP+K P
Sbjct: 1286 ESEPEKAP 1293
Score = 51.6 bits (122), Expect = 6e-06
Identities = 24/87 (27%), Positives = 50/87 (57%), Gaps = 1/87 (1%)
Query: 1006 EIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRS 1065
E+ + G+G S+V + + +LGI+V+ + +G A DGRL DQ+L+++G++
Sbjct: 136 EVFELLKPPSGGLGFSVVGLRSENRGELGIFVQEIQEGSVAHRDGRLKETDQILAINGQA 195
Query: 1066 L-VGLSQERAAELMTRTSSVVTLEVAK 1091
L ++ ++A ++ + V L +A+
Sbjct: 196 LDQTITHQQAISILQKAKDTVQLVIAR 222
Score = 51.6 bits (122), Expect = 6e-06
Identities = 35/108 (32%), Positives = 61/108 (56%), Gaps = 9/108 (8%)
Query: 982 EGADY--ESHLLRENTE--LAQPLRKEPEIITVTLKKQNG-MGLSIVAAKGAGQDKLGIY 1036
+G++Y E L N E + Q + KE T+ + K N +G+++ A K D LG+
Sbjct: 977 KGSEYLLEQSSLACNAECVMLQNVSKESFERTINIAKGNSSLGMTVSANK----DGLGMI 1032
Query: 1037 VKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSV 1084
V+S++ GGA DGR+A GD +LS++ S + ++ +A ++ R S +
Sbjct: 1033 VRSIIHGGAISRDGRIAIGDCILSINEESTISVTNAQARAMLRRHSLI 1080
Score = 49.7 bits (117), Expect = 2e-05
Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 22/131 (16%)
Query: 1013 KKQNGMGLSIVAAKGAGQDKL-GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQ 1071
K Q G+G++I + +D L G+ +KS+ + G A DGRL GDQ+L+VD +VG
Sbjct: 1488 KDQGGLGIAI-----SEEDTLSGVIIKSLTEHGVAATDGRLKVGDQILAVDDEIVVGYPI 1542
Query: 1072 ERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFEL 1131
E+ L+ V L + + +P Q + G+ K+ L
Sbjct: 1543 EKFISLLKTAKMTVKLTI--------------HAENPDSQAVPSAAGAASGEKKNSSQSL 1588
Query: 1132 YNNSTQNGSPE 1142
Q+GSPE
Sbjct: 1589 M--VPQSGSPE 1597
Score = 47.4 bits (111), Expect = 1e-04
Identities = 33/86 (38%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
Query: 1013 KKQNGMGLSIVAAKGAGQDKL--GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLS 1070
K + G+GLSIV G D L I + V + GAA DGRL AGDQ+L V+G L +
Sbjct: 1634 KGRTGLGLSIVG----GSDTLLGAIIIHEVYEEGAACKDGRLWAGDQILEVNGIDLRKAT 1689
Query: 1071 QERAAELMTRTSSVVTLEVAKQGAIY 1096
+ A ++ +T V L + + A Y
Sbjct: 1690 HDEAINVLRQTPQRVRLTLYRDEAPY 1715
Score = 45.4 bits (106), Expect = 4e-04
Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Query: 1013 KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQE 1072
K +G+GLS+ K + ++ +++ + GAA DGRL D+LL ++G+ L G S +
Sbjct: 1355 KGHSGLGLSLAGNKD--RSRMSVFIVGIDPNGAAGKDGRLQIADELLEINGQILYGRSHQ 1412
Query: 1073 RAAELMTRTSSVVTL 1087
A+ ++ S V +
Sbjct: 1413 NASSIIKCAPSKVKI 1427
Score = 40.8 bits (94), Expect = 0.011
Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 10/85 (11%)
Query: 1013 KKQNGMGLSIVAAKGAGQDKLG-----IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLV 1067
K G+G SI+ QD + I ++S+V GG A+ DGRL GD+L+ V+ +L
Sbjct: 705 KGSKGLGFSILDY----QDPIDPASTVIIIRSLVPGGIAEKDGRLLPGDRLMFVNDVNLE 760
Query: 1068 GLSQERAAE-LMTRTSSVVTLEVAK 1091
S E A E L S V + VAK
Sbjct: 761 NSSLEEAVEALKGAPSGTVRIGVAK 785
Score = 39.7 bits (91), Expect = 0.024
Identities = 22/89 (24%), Positives = 45/89 (50%), Gaps = 2/89 (2%)
Query: 1009 TVTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSL 1066
TV +KK + +G+SI G+ + I++ + G A +L GD+++++ G S
Sbjct: 1833 TVEMKKGPTDSLGISIAGGVGSPLGDVPIFIAMMHPTGVAAQTQKLRVGDRIVTICGTST 1892
Query: 1067 VGLSQERAAELMTRTSSVVTLEVAKQGAI 1095
G++ +A L+ S + ++V G +
Sbjct: 1893 EGMTHTQAVNLLKNASGSIEMQVVAGGDV 1921
Score = 37.0 bits (84), Expect = 0.16
Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 9/85 (10%)
Query: 1006 EIITVTLKK---QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVD 1062
EI+ + K +G+G+S+ A G +++SV+ G G+L +GD+LL V+
Sbjct: 550 EIVVAHVSKFSENSGLGISLEATVGHH------FIRSVLPEGPVGHSGKLFSGDELLEVN 603
Query: 1063 GRSLVGLSQERAAELMTRTSSVVTL 1087
G +L+G + + ++ VT+
Sbjct: 604 GITLLGENHQDVVNILKELPIEVTM 628
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 71.6 bits (174), Expect = 6e-12
Identities = 120/543 (22%), Positives = 208/543 (38%), Gaps = 125/543 (23%)
Query: 1139 GSPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKSAYASGTTAKIT 1198
GSP S + +KLPG D ++ V + + G A +G A +
Sbjct: 186 GSPSSSD-------QDEKLPGQDESTAGTSEQNDILKVVEKRIACGPPQAKLNGQQAALA 238
Query: 1199 SVSTGNLCTEEQTPPPRPEAYPIPTQTYTREYFTFPASKSQD----RMAPPQNQWPNYEE 1254
S + PP + YP T FP S S+ R P W + E
Sbjct: 239 SQYRAMM------PPYMFQQYPRMTYPPLHGPMRFPPSLSETNKGLRGRGPPPSWASEPE 292
Query: 1255 KPHMHTDSNHSSIAIQRVTRSQEELREDKAYQLERHRIEAAMDRKSDSDMWIN---QSSS 1311
+P + + S + + E E A ++ D + N +++S
Sbjct: 293 RPSILSASELKEL--DKFDNLDAEADEGWAGAQMEVDYTEQLNFSDDDEQGSNSPKENNS 350
Query: 1312 LDSSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAIPATPVAVSQPI----------- 1360
D + + E N+ +K T + TKS + IPA P P
Sbjct: 351 EDQGSKASE--NNENKKETDEVSNTKSS-------SQIPAQPSVAKVPYGKGPSFNQERG 401
Query: 1361 -RTDLPPPPP------PPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAE----- 1408
+ LPPPP PPP A +P P P PS Q A E
Sbjct: 402 TSSHLPPPPKLLAQQHPPPDRQA---------VPGRPGP------FPSKQQVADEDEIWK 446
Query: 1409 RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPS 1468
+R+R++ + E+AR E E +R E++RK A+++K
Sbjct: 447 QRRRQQSEISAAVERARKRREEEERRMEEQRKAA---------------CAEKLK----- 486
Query: 1469 TLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQ 1528
+ ++ I E QP P I R+ + +R+ +++LEK+Q
Sbjct: 487 --RLDEKLGILEKQP--SPEEIREREREK-------------------EREREKELEKEQ 523
Query: 1529 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDV 1588
+ K+ + Q K +E ++ R++ +K ++ K+K+ + ++E++ ++
Sbjct: 524 EQEREKEREKDRERQQEKEKELEKEQEKQREM------EKERKQEKEKELERQKEKEKEL 577
Query: 1589 DTMLIMQR---LEAERRARDEE-RRRQQQLEEM-RKREAEDRARQEEER--RRQEEERTK 1641
M ++ LE ER +E+ R+ LE M K+E+E+ +EEE RQ+ R++
Sbjct: 578 QKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSE 637
Query: 1642 RDA 1644
++A
Sbjct: 638 KEA 640
Score = 53.1 bits (126), Expect = 2e-06
Identities = 47/236 (19%), Positives = 111/236 (47%), Gaps = 20/236 (8%)
Query: 1420 EKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQR------- 1472
E + ++ E E K+ E T+S + P P A+ + PS Q
Sbjct: 351 EDQGSKASENNENKKETDEVS----NTKSSSQIPAQPSVAKVPYGKGPSFNQERGTSSHL 406
Query: 1473 -PQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMH 1531
P ++ + P + + R + SK++++ D + WK+ +++ E +
Sbjct: 407 PPPPKLLAQQHPPPDRQAVPGRPGPF--PSKQQVADEDEI----WKQRRRQQSEISAAVE 460
Query: 1532 IVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTM 1591
+E +E + + R A +++L++L + ++ Q S ++ + E E++ + +
Sbjct: 461 RARKRREE-EERRMEEQRKAACAEKLKRLDEKLGILEK-QPSPEEIREREREKEREREKE 518
Query: 1592 LIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1647
L ++ + + R+++R RQQ+ E+ ++E E + E+ER++++E+ +R E++
Sbjct: 519 LEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKE 574
Score = 39.7 bits (91), Expect = 0.024
Identities = 36/171 (21%), Positives = 80/171 (46%), Gaps = 13/171 (7%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK-PEK 1466
ER K E R ++EK + E+ + K+RE E++ Q + + L Q+MK EK
Sbjct: 526 EREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEK 585
Query: 1467 PSTLQRPQETVIRELQPQQQ--PRTIERRDLQYITVSKEEL------SSGDSLSPDPWKR 1518
L++ +E + +++P++ +E+++ + +EE S+ P
Sbjct: 586 ECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVH 645
Query: 1519 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR 1569
+ + + Q + ++ K+ Q +S P R + +++++ +WQ Q++
Sbjct: 646 ETEPESGSQPRPAVLSGYFKQFQ--KSLPPRFQRQQEQMKQ--QQWQQQQQ 692
Score = 33.9 bits (76), Expect = 1.3
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 3/104 (2%)
Query: 101 ERRLDIDEK---PLVVQLNWNKDDREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNF 157
+ +L I EK P ++ + +RE L+ E + K+ + + +QEKE ++
Sbjct: 489 DEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKE 548
Query: 158 KRTLSKKEKKEKKKREKEALRQASDKDDRPFQGEDVENSRLAAE 201
+ + EK+ K+++EKE RQ + + E + L E
Sbjct: 549 QEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKE 592
Score = 33.1 bits (74), Expect = 2.3
Identities = 40/163 (24%), Positives = 63/163 (38%), Gaps = 43/163 (26%)
Query: 1352 TPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAAAE 1408
T V +P +T DLPPPPPPP PP P Q P Q
Sbjct: 1043 TEKVVVKPEKTEKKDLPPPPPPPQ----------------PPAPIQPQSVPPPIQ----- 1081
Query: 1409 RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPA--------PFSPLTAQ 1460
E +++ E A L ++ ++ E+ L + T + PA +P+ +
Sbjct: 1082 ----PEAEKFPSTETATL---AQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKE 1134
Query: 1461 QMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKE 1503
+ +PEK + ++ VI +P +P + L T KE
Sbjct: 1135 EKQPEKVIS----KDLVIERPRPDSRPAVKKESTLPPRTYWKE 1173
Score = 31.6 bits (70), Expect = 6.7
Identities = 44/237 (18%), Positives = 83/237 (35%), Gaps = 38/237 (16%)
Query: 1115 DRRGSGKPRPKSEGFELYNNSTQNGSPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSP 1174
D +GS P+ NNS GS S E +E KK + K+ + + P
Sbjct: 338 DEQGSNSPKE--------NNSEDQGSKAS------ENNENKKETDEVSNTKSSSQIPAQP 383
Query: 1175 NVANQPPSPGGKSAYASGTTAKITS----VSTGNLCTEEQTPPPRPEAYPIPTQTYTREY 1230
+VA P G GT++ + ++ + + Q P RP +P Q +
Sbjct: 384 SVAKVPYGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDE 443
Query: 1231 FTFPASKSQDRMAPPQNQWPNYEEKPHMHTDSNHSSIAIQRVTR------------SQEE 1278
+ Q ++ + E+ + + +++ R S EE
Sbjct: 444 IWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEE 503
Query: 1279 LRE-------DKAYQLERHR-IEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSK 1327
+RE ++ +LE+ + E +R+ D + + L+ Q + K
Sbjct: 504 IREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK 560
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 70.9 bits (172), Expect = 1e-11
Identities = 56/259 (21%), Positives = 135/259 (52%), Gaps = 22/259 (8%)
Query: 1408 ERRKREEHQRWYEKEKAR-LEE---ERERKRREQERKLGQ---MRTQSLNPAPFSPLTAQ 1460
E+ +R+E W ++EK R LEE E+E K RE E K+ + +R Q + Q
Sbjct: 349 EKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 408
Query: 1461 QMKPEKPSTLQRPQETVIRELQPQ--QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1518
+ + E+ + + R QE IRE + + +Q + + R++ + K + W++
Sbjct: 409 EKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467
Query: 1519 DAK-----EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRLQE 1572
+ K E ++++MH + + K+ +++ + ++ ++ +++R+ + W+ +++++E
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE 527
Query: 1573 SKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEE----RRRQQQLEEMRK--REAEDRA 1626
++K + EE+ + + M + E+ + +E RR+++++ E + RE +++
Sbjct: 528 QEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Query: 1627 RQEEERRRQEEERTKRDAE 1645
R++EE+ ++EE+ + E
Sbjct: 588 REQEEKIWEQEEKIREQEE 606
Score = 67.8 bits (164), Expect = 8e-11
Identities = 61/259 (23%), Positives = 138/259 (53%), Gaps = 31/259 (11%)
Query: 1411 KREEHQR------WYEKEK-ARLEE---ERERKRREQERKLGQ---MRTQSLNPAPFSPL 1457
++EE R W ++EK RLEE E+E K RE E K+ + +R Q +
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 405
Query: 1458 TAQQMKPEKPSTLQRPQETVIRELQP--QQQPRTIERRDLQYITVSKEELSSGDSLSPDP 1515
Q+ + E+ + + R QE IRE + ++Q + + R++ + K +
Sbjct: 406 REQEKRQEQEAKMWR-QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 464
Query: 1516 WK-----RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKR 1569
W+ R+ +E ++++MH + + K+ +++ + ++ ++ +++R+ + W+ +++
Sbjct: 465 WRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEK 524
Query: 1570 LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQE 1629
++E ++K + EE+ + + M E E + ++E + Q+Q E+MR++ E++ R++
Sbjct: 525 IREQEEKIREQEEKIREQEEMM-----QEQEEKMGEQEEKMQEQ-EKMRRQ--EEKIREQ 576
Query: 1630 EERRRQEEERTKRDAEEKV 1648
EE+ R+++E+ R+ EEK+
Sbjct: 577 EEKIREQKEKI-REQEEKI 594
Score = 67.8 bits (164), Expect = 8e-11
Identities = 49/250 (19%), Positives = 127/250 (50%), Gaps = 17/250 (6%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1462
++ E+R+ +E + W ++EK R E+E K REQE+K+ + + +Q
Sbjct: 404 KIREQEKRQEQEAKMWRQEEKIR---EQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE 460
Query: 1463 KPE--KPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDP----W 1516
+ E + R QE + R+ + + I +++ + + +E++ + + W
Sbjct: 461 QEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE-EKVWRQEEKMHDQEEKIREQEEKMW 519
Query: 1517 KRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK 1576
+++ K + ++++ + + ++ + +Q + ++ E+ +++++ Q + R QE K +
Sbjct: 520 RQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQE-----QEKMRRQEEKIR 574
Query: 1577 DEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQE 1636
+++++ E + + E E + R++E Q+Q E+M E E++ ++EE+ +++
Sbjct: 575 EQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW--EQEEKMCEQEEKMQEQ 632
Query: 1637 EERTKRDAEE 1646
EE+ +R E+
Sbjct: 633 EEKMRRQEEK 642
Score = 60.8 bits (146), Expect = 1e-08
Identities = 55/257 (21%), Positives = 123/257 (47%), Gaps = 28/257 (10%)
Query: 1394 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAP 1453
A+ +G V+A + + EE++ W RL +++E K QE K+ + +
Sbjct: 267 ADHLGKELQSVSAKLQAQVEENELWN-----RLNQQQEEKMWRQEEKIQEWEEK------ 315
Query: 1454 FSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1513
+ Q+ K + R QE +R + + + R + + KEE L
Sbjct: 316 ---IQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR--RLEE 370
Query: 1514 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1573
W+++ K + E +++MH + + +E +E + + ++ E+ R + W+ +++++E
Sbjct: 371 MMWEKEEKIR-ELEEKMHEQEKI-REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 428
Query: 1574 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQE--EE 1631
++K + E++ +++ + + R+EE+R++Q EEM ++E + R ++E +
Sbjct: 429 EEKIREQEKK------MWRQEEKIHEQEKIREEEKRQEQ--EEMWRQEEKIREQEEIWRQ 480
Query: 1632 RRRQEEERTKRDAEEKV 1648
+ + E+ R EEKV
Sbjct: 481 KEKMHEQEKIRKQEEKV 497
Score = 59.7 bits (143), Expect = 2e-08
Identities = 51/246 (20%), Positives = 126/246 (51%), Gaps = 46/246 (18%)
Query: 1408 ERRKREEHQRWYEKEKARLEEE---RERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1464
E +++E+ + W ++EK R +EE ++ K EQE+ + Q+ K
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEK-----------------IRKQEEKV 497
Query: 1465 EKPSTLQRPQETVIRELQPQ--QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR--DA 1520
+ QE IRE + + +Q I ++ + I +E++ + + + ++ +
Sbjct: 498 WRQEEKMHDQEEKIREQEEKMWRQEEKIREQE-EKIREQEEKIREQEEMMQEQEEKMGEQ 556
Query: 1521 KEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRLQESKQKDED 1579
+EK+++Q++M ++ ++++ + ++ E+ +++R+ + W+ +++++E Q++
Sbjct: 557 EEKMQEQEKMR------RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE--QEEMM 608
Query: 1580 DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEER 1639
E+EE + E E + ++E + Q+Q E+MR++ E++ ++E R RQ+EE+
Sbjct: 609 QEQEE----------KMWEQEEKMCEQEEKMQEQEEKMRRQ--EEKMWEQEVRLRQQEEK 656
Query: 1640 TKRDAE 1645
+ E
Sbjct: 657 MQEHQE 662
Score = 52.4 bits (124), Expect = 4e-06
Identities = 50/215 (23%), Positives = 104/215 (48%), Gaps = 48/215 (22%)
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK---------- 1517
+T ++ + I EL ++ ++E L T++ EEL ++ + +
Sbjct: 185 ATQKKKADRYIEELTKERDALSLE---LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 241
Query: 1518 ---RDAKEKLEK------QQQMHI-VDMLSKEIQELQSKPDRSAEESDRLRKLMLE---- 1563
++ K KLE+ QQQ+ D L KE+Q + +K EE++ +L +
Sbjct: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 301
Query: 1564 -WQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREA 1622
W+ ++++QE ++K ++ EE+ ++ E + R ++E+ RRQ+++ E
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEK----------IREQEEKIREQEEKMRRQEEM----MWEK 347
Query: 1623 EDRARQEEERRRQEEERTKR------DAEEKVMVL 1651
E++ R++EE ++EE+ +R + EEK+ L
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382
Score = 45.4 bits (106), Expect = 4e-04
Identities = 52/240 (21%), Positives = 110/240 (45%), Gaps = 34/240 (14%)
Query: 1411 KREEHQRWYEKEKARLE-EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPST 1469
K +E + E EK+ ++ +E KR+ + KL L QQ +
Sbjct: 225 KLQEKLQLVESEKSEIQLNVKELKRKLERAKL---------------LLPQQQLQAEADH 269
Query: 1470 LQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQ 1529
L + ++V +LQ Q + + R + +EE W+ +E+ EK ++
Sbjct: 270 LGKELQSVSAKLQAQVEENELWNR----LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE 325
Query: 1530 MHIVDMLSKEIQELQSKPDRSAEESDRLRKLM-LEWQFQKRLQESKQKDEDDEEEEDDDV 1588
+ + ++ ++++ + + E+ +++R+ + W+ +++++ ++ + EE+ +
Sbjct: 326 QE--EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE 383
Query: 1589 DTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKV 1648
+ M E E+ EE+R+ EE + RE E R QE + RQEE+ R+ EEK+
Sbjct: 384 EKMH-----EQEKIREQEEKRQ----EEEKIREQEKRQEQEAKMWRQEEK--IREQEEKI 432
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/176 (19%), Positives = 82/176 (46%), Gaps = 19/176 (10%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
E+ + +E + W ++EK R E+E K REQE K+ + + + + Q+ K ++
Sbjct: 509 EKIREQEEKMWRQEEKIR---EQEEKIREQEEKIREQ--EEMMQEQEEKMGEQEEKMQEQ 563
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1527
++R +E + + + ++ + R + I +E++ + + ++ +EK+ +Q
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMM-----QEQEEKMWEQ 618
Query: 1528 QQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEE 1583
++ ++ E + K E+ R + M E + + R QE K ++ + E
Sbjct: 619 EE---------KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLE 665
Score = 42.4 bits (98), Expect = 0.004
Identities = 45/237 (18%), Positives = 102/237 (43%), Gaps = 13/237 (5%)
Query: 1420 EKEKARLEEERERKRREQERKLGQMR------TQSLNPAPFSPLTAQQMKPEKPSTLQRP 1473
E E+ + +E RRE E ++ +R T+ +S +Q++ E + R
Sbjct: 108 EDEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRL 167
Query: 1474 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-----DAKEKLEKQQ 1528
++ + +Q + + + +E D+LS + ++ + KEK K Q
Sbjct: 168 HDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQ 227
Query: 1529 QMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDV 1588
+ + ++ E E+Q + +R + L+ + Q Q ++ + + V
Sbjct: 228 EK--LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQV 285
Query: 1589 DTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
+ + RL ++ + + + Q E + +E E++ R++EE+ R++EE+ +R E
Sbjct: 286 EENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEE 342
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 70.9 bits (172), Expect = 1e-11
Identities = 53/246 (21%), Positives = 119/246 (48%), Gaps = 27/246 (10%)
Query: 1408 ERRKREEHQRWYEKEKARLE---EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKP 1464
E R RE+ + W + EK R E +E+E+K R+QE K+ + + ++ K
Sbjct: 410 EERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER----------IREREKKM 459
Query: 1465 EKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-DAKEK 1523
+ R QE +++ + + + Q + KE+L + + K + +EK
Sbjct: 460 REEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEK 519
Query: 1524 LEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQKRLQESKQKDEDDEE 1582
+ Q++M + ++++ + D+ E+ +++R + W ++R+++ Q+ E
Sbjct: 520 IRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 1583 EEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKR 1642
++++ ++ E R R+ E++ +++ E MR++E + QE+E + QE+E
Sbjct: 580 DQEE---------KMREEERMREREKKMREEEEMMREQEEK---MQEQEEKMQEQEEKMW 627
Query: 1643 DAEEKV 1648
+ EEK+
Sbjct: 628 EQEEKM 633
Score = 68.2 bits (165), Expect = 6e-11
Identities = 53/236 (22%), Positives = 117/236 (49%), Gaps = 32/236 (13%)
Query: 1414 EHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRP 1473
+ + W ++E+ R E+E+K R+QE K+ + + L Q+ K +
Sbjct: 271 QEEMWRQEEELR---EQEKKIRKQEEKMWRQEER---------LREQEGKMREQEEKMWR 318
Query: 1474 QETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSL--SPDPWKRDAKEKLEKQQQM- 1530
QE +RE + + + + E R+ + + +E++ + + R+ +EK+ +Q++
Sbjct: 319 QEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL 378
Query: 1531 -HIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVD 1589
+ ++ Q+++ + +R E+ +RLR+ + Q+++ E +K ++++ +
Sbjct: 379 WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQ----- 433
Query: 1590 TMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
E E++ RD+E + Q EE R RE E + R+EEE R++EE+ ++ E
Sbjct: 434 --------EQEKKTRDQEEKMQ---EEERIREREKKMREEEETMREQEEKMQKQEE 478
Score = 68.2 bits (165), Expect = 6e-11
Identities = 53/250 (21%), Positives = 121/250 (48%), Gaps = 23/250 (9%)
Query: 1408 ERRKREEHQRWYEKEKA----RLEEERER-----KRREQERKLGQMRTQSLNPAPFSPLT 1458
E+ +++E W ++EK RL E++E+ K +EQE K+ + + +
Sbjct: 471 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 530
Query: 1459 AQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1518
+ + EK +RE + Q + + RD + +EE + +
Sbjct: 531 KKMWRQEK-----------MREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTW 579
Query: 1519 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE--WQFQKRLQESKQK 1576
D +EK+ ++++M + +E +E+ + + +E + + E W+ ++++QE ++K
Sbjct: 580 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEK 639
Query: 1577 DEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQE 1636
+ EE+ + + M QRL E++ + E + Q+ E+M+++E + +++ E++ QE
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRL-PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698
Query: 1637 EERTKRDAEE 1646
+E+ D E+
Sbjct: 699 QEKKTWDQEK 708
Score = 67.4 bits (163), Expect = 1e-10
Identities = 57/242 (23%), Positives = 122/242 (50%), Gaps = 25/242 (10%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
E + RE+ ++ + +EK E+E+E REQE++L + + L Q+ + ++
Sbjct: 306 EGKMREQEEKMWRQEKRLREQEKEL--REQEKELREQK----------ELREQEEQMQEQ 353
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQ 1527
QE +RE Q ++ R ER Q + ++E D W++D + + EK+
Sbjct: 354 EEKMWEQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMRDQ-EERMWEQDERLR-EKE 410
Query: 1528 QQMHIVDMLSKEIQELQSKPDRSAEES---DRLRKLMLEWQFQKRLQESKQKDEDDEEEE 1584
++M + + +++++++ + +E D+ K+ E + ++R ++ ++++E E+E
Sbjct: 411 ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQE 470
Query: 1585 DDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDA 1644
+ MQ+ E ++E+ +QQ+L E +++ E QE+E + E+E RD
Sbjct: 471 EK-------MQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 523
Query: 1645 EE 1646
EE
Sbjct: 524 EE 525
Score = 65.5 bits (158), Expect = 4e-10
Identities = 56/256 (21%), Positives = 130/256 (50%), Gaps = 34/256 (13%)
Query: 1408 ERRKREEHQRWYEKEKARLEEE---------RERKRREQERKLGQMRTQSLNPAPFSPLT 1458
E+ + +E + W ++EK R +EE R+ K REQE ++ + + + +
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE--QKMW 561
Query: 1459 AQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1518
Q+ + EK T ++ ++T +E + +++ R ER +EE + R
Sbjct: 562 DQEERMEK-KTQEQEKKTWDQEEKMREEERMREREKKM-----REE---------EEMMR 606
Query: 1519 DAKEKLEKQQQ--MHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQK 1576
+ +EK+++Q++ + + ++ +++Q + ++ E+ +++ + + Q+RL E K+K
Sbjct: 607 EQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK 666
Query: 1577 ---DEDDEEEEDDDVDTMLIMQRLEAERRARDEERR---RQQQLEEMRKREAEDRARQEE 1630
E +E+E I ++ + E++ +++E++ +++ EE RE E + R+EE
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEE 726
Query: 1631 ERRRQEEERTKRDAEE 1646
E R++EE+ + E+
Sbjct: 727 EMMREQEEKMQEQEEK 742
Score = 65.1 bits (157), Expect = 5e-10
Identities = 60/260 (23%), Positives = 129/260 (49%), Gaps = 41/260 (15%)
Query: 1408 ERRKREEHQRWYEKEKARLEEER-----------ERKRREQERKLGQMRTQSLNPAPFSP 1456
E+ + +E + W ++EK R +EE+ E++ REQE+K MR Q
Sbjct: 348 EQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK---MRDQE------ER 398
Query: 1457 LTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIER-----RDLQYITVSKEELSSGDSL 1511
+ Q + + R QE + +++ ++ + ++ RD + +E + +
Sbjct: 399 MWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKK 458
Query: 1512 --SPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKR 1569
+ R+ +EK++KQ++ +M +E +E Q + R E+ ++L W+ Q++
Sbjct: 459 MREEEETMREQEEKMQKQEE----NMWEQEEKEWQQQ--RLPEQKEKL------WE-QEK 505
Query: 1570 LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQE 1629
+QE ++K + EE+ D + +++ + + R++E + +Q E+MR +E + ++E
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 565
Query: 1630 E-ERRRQEEERTKRDAEEKV 1648
E++ QE+E+ D EEK+
Sbjct: 566 RMEKKTQEQEKKTWDQEEKM 585
Score = 61.6 bits (148), Expect = 6e-09
Identities = 58/257 (22%), Positives = 127/257 (49%), Gaps = 22/257 (8%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQ----MRTQSLNPAPFSPLTAQQMK 1463
E++ R++ ++ E+E+ R ERE+K RE+E + + M+ Q N QQ +
Sbjct: 436 EKKTRDQEEKMQEEERIR---EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492
Query: 1464 -PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDP---WKRD 1519
PE+ L ++ +E + +Q I RD + + ++++ + + W+++
Sbjct: 493 LPEQKEKLWEQEKMQEQEEKIWEQEEKI--RDQEEMWGQEKKMWRQEKMREQEDQMWEQE 550
Query: 1520 AKEKLEKQQQMHIVDMLSKEIQELQSKP---DRSAEESDRLR---KLMLEWQFQKRLQES 1573
K + ++Q+ + + K+ QE + K + E +R+R K M E + R QE
Sbjct: 551 EKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE 610
Query: 1574 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEM--RKREAEDRARQEEE 1631
K ++++++ +E ++ + E E + ++E + +Q E+M ++R E + + E
Sbjct: 611 KMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEH 670
Query: 1632 RRRQEEERTKRDAEEKV 1648
+ QE+E+ + + EEK+
Sbjct: 671 EKMQEQEKMQ-EQEEKI 686
Score = 61.2 bits (147), Expect = 8e-09
Identities = 52/251 (20%), Positives = 119/251 (47%), Gaps = 20/251 (7%)
Query: 1399 LPSAQVAAAERRKREEHQRWYEKEKARLEEER-ERKRREQERKLGQMRTQSLNPAPFSPL 1457
LP + E K +E ++ E+E+ E+E+ E+K +EQE+K + +
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES----M 715
Query: 1458 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1517
++ K + + R QE ++E + + Q + E + + +EE P+
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQ-- 773
Query: 1518 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
KEKL + ++M + + ++ ++++ + ++ + +++R + + Q+ +++
Sbjct: 774 ---KEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830
Query: 1578 EDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEE 1637
+EE+ M E + ++E+ + Q +E + RE E++ R +EE+ R++E
Sbjct: 831 MWGQEEK---------MWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE 881
Query: 1638 ERTKRDAEEKV 1648
E+ R EEK+
Sbjct: 882 EK-MRGQEEKI 891
Score = 60.8 bits (146), Expect = 1e-08
Identities = 50/242 (20%), Positives = 116/242 (47%), Gaps = 25/242 (10%)
Query: 1408 ERRKREEHQRWYEKEKARLEEER--------ERKRREQERKLGQMRTQSLNPAPFSPLTA 1459
E+ + +E Q W ++EK R +E++ E+K +EQE+K + +
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE---ERMRE 593
Query: 1460 QQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRD 1519
++ K + + R QE ++E + + Q + + + + +EE W+++
Sbjct: 594 REKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM---------WEQE 644
Query: 1520 AKEKLEKQQQMHIVDMLSKEIQEL--QSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
K E++++M L ++ ++L K + ++ K+ + + +K+ QE ++K
Sbjct: 645 EK-MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKT 703
Query: 1578 EDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEE 1637
D E+ +++ + E E R++E + Q+Q E+M+++E E ++EE+ ++E
Sbjct: 704 WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE--MWEQEEKMWEQE 761
Query: 1638 ER 1639
E+
Sbjct: 762 EK 763
Score = 48.5 bits (114), Expect = 5e-05
Identities = 37/152 (24%), Positives = 84/152 (55%), Gaps = 32/152 (21%)
Query: 1509 DSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLE-WQFQ 1567
++L + W+++ E+L +Q++ + K+ +++ + +R E+ ++R+ + W+ +
Sbjct: 268 NTLQEEMWRQE--EELREQEKK-----IRKQEEKMWRQEERLREQEGKMREQEEKMWRQE 320
Query: 1568 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEM-----RKREA 1622
KRL+E +++ + E+E L ++ R++E + Q+Q E+M + RE
Sbjct: 321 KRLREQEKELREQEKE-------------LREQKELREQEEQMQEQEEKMWEQEEKMREQ 367
Query: 1623 EDRA-RQEE-----ERRRQEEERTKRDAEEKV 1648
E++ RQEE E++ +E+E+ RD EE++
Sbjct: 368 EEKMWRQEERLWEQEKQMREQEQKMRDQEERM 399
>gi|93204861 protein phosphatase 1, regulatory (inhibitor) subunit 9A
[Homo sapiens]
Length = 1098
Score = 70.5 bits (171), Expect = 1e-11
Identities = 38/91 (41%), Positives = 59/91 (64%), Gaps = 4/91 (4%)
Query: 1006 EIITVTLKK-QNGMGLSIVA---AKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1061
E+ V L+K ++G+G+SI+ AG +KLGI+VK+V +GGAA DGR+ DQ++ V
Sbjct: 501 ELFPVELEKDEDGLGISIIGMGVGADAGLEKLGIFVKTVTEGGAAQRDGRIQVNDQIVEV 560
Query: 1062 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1092
DG SLVG++Q AA ++ T V + ++
Sbjct: 561 DGISLVGVTQNFAATVLRNTKGNVRFVIGRE 591
Score = 33.9 bits (76), Expect = 1.3
Identities = 49/228 (21%), Positives = 95/228 (41%), Gaps = 17/228 (7%)
Query: 1391 PPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQS-- 1448
P +++ +Q ERR+RE ++ Y + A +E E E+E ++G + S
Sbjct: 593 PGQVSEVAQLISQTLEQERRQRELLEQHYAQYDADDDETGEYATDEEEDEVGPVLPGSDM 652
Query: 1449 --------LNPAPFSPLTAQQMK-PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYIT 1499
N FSP K K LQ E+Q + +
Sbjct: 653 AIEVFELPENEDMFSPSELDTSKLSHKFKELQIKHAVTEAEIQKLKTKLQAAENEKVRWE 712
Query: 1500 VSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRK 1559
+ K +L + + + +E Q H V ++ ++E QS+ ++ ++ +K
Sbjct: 713 LEKTQLQQNIEENKERMLKLESYWIEAQTLCHTV---NEHLKETQSQYQALEKKYNKAKK 769
Query: 1560 LMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEE 1607
L+ ++Q QK L K+++ + ++ ED + ++ +Q L+ R RD E
Sbjct: 770 LIKDFQ-QKELDFIKRQEAERKKIEDLEKAHLVEVQGLQV--RIRDLE 814
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 70.1 bits (170), Expect = 2e-11
Identities = 52/243 (21%), Positives = 119/243 (48%), Gaps = 38/243 (15%)
Query: 1408 ERRKREEHQRWYEKEKARLEEE----RERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK 1463
E+ +R+E W ++EK R +EE +E K RE E K+ + + Q+ K
Sbjct: 316 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEK----------IREQEEK 365
Query: 1464 PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEK 1523
R +E IRE + +Q+ R + I +E++ + + ++ +EK
Sbjct: 366 --------RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM-----QEQEEK 412
Query: 1524 LEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEE 1583
+ +Q++ + ++ +E+Q + ++ + +++R+ +K+++E ++K + EE
Sbjct: 413 MGEQEEK-----MWEQEEEMQEQEEKMRRQEEKIREQ------EKKIREQEEKIREQEEM 461
Query: 1584 EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRD 1643
+ + M + E+ A+ +E+ + + +E + RE E + R++EE+ R++EE +
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521
Query: 1644 AEE 1646
E+
Sbjct: 522 EEK 524
Score = 62.4 bits (150), Expect = 4e-09
Identities = 55/258 (21%), Positives = 120/258 (46%), Gaps = 49/258 (18%)
Query: 1394 ANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAP 1453
A+ +G V+A + + EE++ W RL +++E K QE K+ + +
Sbjct: 255 ADHLGKELQSVSAKLQAQVEENELWN-----RLNQQQEEKMWRQEEKIQEREEK------ 303
Query: 1454 FSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSP 1513
+ Q+ K + R QE ++ E + + RR + + +E++
Sbjct: 304 ---IQEQEEKIREQEEKMRRQEEMMWEKEEKM------RRQEEMMWEKEEKI-------- 346
Query: 1514 DPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQES 1573
R+ +EK+ +Q+++ +E +E + + ++ E+ R + W+ +++++E
Sbjct: 347 ----RELEEKMHEQEKI-------REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 395
Query: 1574 KQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRK-----REAEDRARQ 1628
++K + EE + + M E E + ++E Q+Q E+MR+ RE E + R+
Sbjct: 396 EEKIREQEEMMQEQEEKMG-----EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIRE 450
Query: 1629 EEERRRQEEERTKRDAEE 1646
+EE+ R++EE + E+
Sbjct: 451 QEEKIREQEEMMQEQEEK 468
Score = 60.8 bits (146), Expect = 1e-08
Identities = 53/209 (25%), Positives = 105/209 (50%), Gaps = 37/209 (17%)
Query: 1468 STLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK---------- 1517
+T ++ + I EL ++ ++E L T++ EEL ++ + +
Sbjct: 173 ATQKKKADRYIEELTKERDALSLE---LYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 229
Query: 1518 ---RDAKEKLEK------QQQMHI-VDMLSKEIQELQSKPDRSAEESDRLRKLMLE---- 1563
++ K KLE+ QQQ+ D L KE+Q + +K EE++ +L +
Sbjct: 230 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 289
Query: 1564 -WQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQL---EEMRK 1619
W+ ++++QE ++K ++ EE+ + + M +R E ++E+ RRQ+++ +E +
Sbjct: 290 MWRQEEKIQEREEKIQEQEEKIREQEEKM---RRQEEMMWEKEEKMRRQEEMMWEKEEKI 346
Query: 1620 REAEDRARQEEERRRQEEERTKRDAEEKV 1648
RE E++ ++E+ R QEE KR EEK+
Sbjct: 347 RELEEKMHEQEKIREQEE---KRQEEEKI 372
Score = 53.5 bits (127), Expect = 2e-06
Identities = 63/258 (24%), Positives = 131/258 (50%), Gaps = 35/258 (13%)
Query: 1411 KREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNP----------APFSPLTAQ 1460
K +E + E EK+ ++ + +R+ ER + Q L + + L AQ
Sbjct: 213 KLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ 272
Query: 1461 QMKPEKPSTLQRPQETVI--RELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1518
+ E + L + QE + +E + Q++ I+ ++ + I +E++ + + W++
Sbjct: 273 VEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQE-EKIREQEEKMRRQEEMM---WEK 328
Query: 1519 DAKEKLEKQQQMHIVDMLSKE--IQELQSKPDRSA----EESDRLRKLMLEWQFQKRLQE 1572
+ EK+ +Q++M M KE I+EL+ K +E R + + Q +++ QE
Sbjct: 329 E--EKMRRQEEM----MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 382
Query: 1573 SK--QKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEE 1630
+K +++E E+E+ + +MQ E E + ++E + +Q EEM +E E++ R++E
Sbjct: 383 AKMWRQEEKIREQEEKIREQEEMMQ--EQEEKMGEQEEKMWEQEEEM--QEQEEKMRRQE 438
Query: 1631 ERRRQEEERTKRDAEEKV 1648
E+ R++E++ R+ EEK+
Sbjct: 439 EKIREQEKKI-REQEEKI 455
Score = 32.3 bits (72), Expect = 3.9
Identities = 30/159 (18%), Positives = 77/159 (48%), Gaps = 31/159 (19%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQM 1462
++ E++ RE+ ++ E+E+ + +E+E K EQE K+ + Q+
Sbjct: 440 KIREQEKKIREQEEKIREQEE--MMQEQEEKMGEQEGKMCE----------------QEA 481
Query: 1463 KPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAK- 1521
K ++ R QE IRE + + + + + R+ + + +EE W+++ K
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE---------KMWEQEEKM 532
Query: 1522 -EKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRK 1559
E+ EK Q+ + + ++ ++++ + R ++ +++++
Sbjct: 533 CEQEEKMQEQE--EKMRRQEEKMREQEVRLRQQEEKMQE 569
>gi|112382257 InaD-like [Homo sapiens]
Length = 1801
Score = 69.3 bits (168), Expect = 3e-11
Identities = 37/88 (42%), Positives = 54/88 (61%), Gaps = 6/88 (6%)
Query: 1006 EIITVTLKKQ--NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDG 1063
EI V L+K+ G+GLSIV + G+++ +VKGGAAD+DGRL GDQ+LSV+G
Sbjct: 1530 EIFPVDLQKKAGRGLGLSIVGKRNGS----GVFISDIVKGGAADLDGRLIQGDQILSVNG 1585
Query: 1064 RSLVGLSQERAAELMTRTSSVVTLEVAK 1091
+ SQE A ++ +V LE+ +
Sbjct: 1586 EDMRNASQETVATILKCAQGLVQLEIGR 1613
Score = 54.7 bits (130), Expect = 7e-07
Identities = 27/79 (34%), Positives = 47/79 (59%), Gaps = 5/79 (6%)
Query: 1016 NGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAA 1075
+G+G IV K +G + V+++V GG AD DGRL GD +L + G ++ G++ E+ A
Sbjct: 256 SGLGFGIVGGKTSG-----VVVRTIVPGGLADRDGRLQTGDHILKIGGTNVQGMTSEQVA 310
Query: 1076 ELMTRTSSVVTLEVAKQGA 1094
+++ + V + VA+ A
Sbjct: 311 QVLRNCGNSVRMLVARDPA 329
Score = 54.7 bits (130), Expect = 7e-07
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 26/163 (15%)
Query: 1013 KKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQE 1072
K +NG+GLS+ K + ++ I+V + G A DGR+ GD+LL ++ + L G S +
Sbjct: 1244 KDKNGLGLSLAGNKD--RSRMSIFVVGINPEGPAAADGRMRIGDELLEINNQILYGRSHQ 1301
Query: 1073 RAAELM-TRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSG----------- 1120
A+ ++ T S V + + + A+ T PS I D+ G+
Sbjct: 1302 NASAIIKTAPSKVKLVFIRNEDAVNQMAVTPFPVPSSSPSSIEDQSGTEPISSEEDGSVE 1361
Query: 1121 ---KPRPKSEGFEL---------YNNSTQNGSPESPQLPWAEY 1151
K P+SE F+L Y S E P P + Y
Sbjct: 1362 VGIKQLPESESFKLAVSQMKQQKYPTKVSFSSQEIPLAPASSY 1404
Score = 53.9 bits (128), Expect = 1e-06
Identities = 43/130 (33%), Positives = 60/130 (46%), Gaps = 11/130 (8%)
Query: 1000 PLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLL 1059
P+ E+I K ++G+GLSIV K + I + V + GAA DGRL AGDQ+L
Sbjct: 1429 PIVPGQEMIIEISKGRSGLGLSIVGGKDTPLN--AIVIHEVYEEGAAARDGRLWAGDQIL 1486
Query: 1060 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQR------- 1112
V+G L S E A + +T V L V + A Y L P + ++
Sbjct: 1487 EVNGVDLRNSSHEEAITALRQTPQKVRLVVYRDEAHYRDEENLEIFPVDLQKKAGRGLGL 1546
Query: 1113 --ISDRRGSG 1120
+ R GSG
Sbjct: 1547 SIVGKRNGSG 1556
Score = 51.6 bits (122), Expect = 6e-06
Identities = 35/117 (29%), Positives = 60/117 (51%), Gaps = 7/117 (5%)
Query: 977 WTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIY 1036
WT D+ S + ++AQ ++ E I + G+G S+VA + K+ I+
Sbjct: 110 WTPKLGNEDFNSVI----QQMAQG--RQIEYIDIERPSTGGLGFSVVALRSQNLGKVDIF 163
Query: 1037 VKSVVKGGAADVDGRLAAGDQLLSVDGRSL-VGLSQERAAELMTRTSSVVTLEVAKQ 1092
VK V G AD D RL DQ+L+++ L +S ++A L+ +T+ + L VA++
Sbjct: 164 VKDVQPGSVADRDQRLKENDQILAINHTPLDQNISHQQAIALLQQTTGSLRLIVARE 220
Score = 47.4 bits (111), Expect = 1e-04
Identities = 27/91 (29%), Positives = 49/91 (53%), Gaps = 4/91 (4%)
Query: 1006 EIITVTLKKQNG--MGLSIVAAKGAGQ--DKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1061
E V L +++G +G+ IV G + GIYVKS++ G AA +G + D++++V
Sbjct: 362 ETYNVELVRKDGQSLGIRIVGYVGTSHTGEASGIYVKSIIPGSAAYHNGHIQVNDKIVAV 421
Query: 1062 DGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1092
DG ++ G + E++ VV L + ++
Sbjct: 422 DGVNIQGFANHDVVEVLRNAGQVVHLTLVRR 452
Score = 44.3 bits (103), Expect = 0.001
Identities = 20/86 (23%), Positives = 43/86 (50%)
Query: 1004 EPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDG 1063
EP + + + + +G+SI +G+ + +++ + G A +L GD+++S++G
Sbjct: 1673 EPRTVEINRELSDALGISIAGGRGSPLGDIPVFIAMIQASGVAARTQKLKVGDRIVSING 1732
Query: 1064 RSLVGLSQERAAELMTRTSSVVTLEV 1089
+ L GLS L+ + L+V
Sbjct: 1733 QPLDGLSHADVVNLLKNAYGRIILQV 1758
Score = 40.0 bits (92), Expect = 0.019
Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 14/135 (10%)
Query: 1005 PEIITVTLKKQNGMGLSIVAAKGA------GQDKLGIYVKSVVKGGAADVDGRLAAGDQL 1058
P I+ + + +G+SIV + G++ GI++K V++ A L GD++
Sbjct: 1066 PRIVEIFREPNVSLGISIVGGQTVIKRLKNGEELKGIFIKQVLEDSPAGKTNALKTGDKI 1125
Query: 1059 LSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAI------YHGLATLL--NQPSPMM 1110
L V G L S A E + + V V + H A + NQ
Sbjct: 1126 LEVSGVDLQNASHSEAVEAIKNAGNPVVFIVQSLSSTPRVIPNVHNKANKITGNQNQDTQ 1185
Query: 1111 QRISDRRGSGKPRPK 1125
++ R+G+ P K
Sbjct: 1186 EKKEKRQGTAPPPMK 1200
Score = 39.3 bits (90), Expect = 0.032
Identities = 31/108 (28%), Positives = 51/108 (47%), Gaps = 13/108 (12%)
Query: 983 GADYESHLLRENTELAQP--LRKEPEIITV-TLKKQNGMGLSIVAAKGAGQDKLGIYVKS 1039
G DYE + +T++A L+K +++ + TL+ +G+ + + G Y+ S
Sbjct: 536 GPDYEVMVATLDTQIADDAELQKYSKLLPIHTLR----LGVEVDSFDGHH------YISS 585
Query: 1040 VVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTL 1087
+V GG D G L D+LL V+G L G S+ A + TL
Sbjct: 586 IVSGGPVDTLGLLQPEDELLEVNGMQLYGKSRREAVSFLKEVPPPFTL 633
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 68.9 bits (167), Expect = 4e-11
Identities = 79/311 (25%), Positives = 132/311 (42%), Gaps = 31/311 (9%)
Query: 1349 IPATPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVA 1405
IP+ +VS P +L P P V G + +D P P L A+ A
Sbjct: 670 IPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAA 729
Query: 1406 AAE--------RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1457
E R KREE +R ++E R +EE R+++E+ERK R + A
Sbjct: 730 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK----RREEEELARRKQE 785
Query: 1458 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1517
A + + E+ L+R +E R+ Q + R ERR + +EEL W
Sbjct: 786 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 845
Query: 1518 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
R+ +E + ++ + + +E L+ EE +R RK LE Q QK L +Q+
Sbjct: 846 REEEEAQRRLEENRL--RMEEEAARLRH------EEEERKRK-ELEVQRQKELMRQRQQQ 896
Query: 1578 ED-----DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLE--EMRKREAEDRARQEE 1630
++ ++++ + M + +++ + Q L E++K E E + E
Sbjct: 897 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE 956
Query: 1631 ERRRQEEERTK 1641
E+RRQ+ E K
Sbjct: 957 EQRRQQRELMK 967
Score = 62.4 bits (150), Expect = 4e-09
Identities = 65/234 (27%), Positives = 112/234 (47%), Gaps = 24/234 (10%)
Query: 1416 QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE 1475
Q+ Y + A+ ++ +++Q+ L + Q+L ++ Q + P ++ P
Sbjct: 627 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMR----ISDQNIIPSVTRSVSVPDT 682
Query: 1476 TVIRELQPQ-QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1534
I ELQP QP E + + + D+ +P P A E+L++ ++
Sbjct: 683 GSIWELQPTASQPTVWEGGSVWDLPL--------DTTTPGP----ALEQLQQLEKAKAAK 730
Query: 1535 MLSKEIQELQSKPDRSAEESDRLRKLMLEWQ-FQKRLQESKQKDEDDEEEEDDDVDTMLI 1593
L +E +E + + R EE R +L + + +R QE ++K ++EE + L
Sbjct: 731 -LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 789
Query: 1594 MQRLE--AERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
QR + A RR R+EE R+QQ E R E+R R+EEERR+QEE K++ E
Sbjct: 790 RQREQEIALRRQREEEERQQQ---EEALRRLEERRREEEERRKQEELLRKQEEE 840
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/58 (44%), Positives = 38/58 (65%)
Query: 1592 LIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKVM 1649
L +R EAE RA+ EE R++Q E R++E R +QEEER+R+EEE R +E+ +
Sbjct: 731 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL 788
Score = 46.6 bits (109), Expect = 2e-04
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 9/83 (10%)
Query: 1568 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRAR 1627
++L+++K + E E + + + E E R R EE RRQQ+ E +R+++ E+R R
Sbjct: 721 QQLEKAKAAKLEQERREAE------MRAKREEEERKRQEELRRQQE-EILRRQQEEERKR 773
Query: 1628 QEEER--RRQEEERTKRDAEEKV 1648
+EEE RR++EE +R E+++
Sbjct: 774 REEEELARRKQEEALRRQREQEI 796
Score = 36.2 bits (82), Expect = 0.27
Identities = 24/121 (19%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Query: 139 KAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAL-RQASDKDDRPFQGEDVENSR 197
+A+ E++ +E + + + L +++++E+K+RE+E L R+ ++ R + +++ R
Sbjct: 741 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 800
Query: 198 LAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSL 257
E + E + R +RR+Q++L ++ +E + R + R+ + L
Sbjct: 801 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 860
Query: 258 K 258
+
Sbjct: 861 R 861
Score = 34.7 bits (78), Expect = 0.79
Identities = 62/273 (22%), Positives = 110/273 (40%), Gaps = 52/273 (19%)
Query: 1422 EKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK------PEKPS----TLQ 1471
E +LEEERER+ RE++R+ + + L A QQ K KPS +L
Sbjct: 942 EIQKLEEERERQLREEQRR----QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 997
Query: 1472 RPQETVIRELQPQQQPRTIERRD--LQYITVSKEELSSGDSL-------SPDPWKRDAKE 1522
Q+ R++Q QQQ + ++ + T S S G+S+ P+ W D
Sbjct: 998 EIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVS 1057
Query: 1523 KL-----EKQQQMHIVDMLSKEIQELQSKP--------DRSAEESDRLRKLMLEWQFQKR 1569
+ K M D KE+ S +S S+R K + E + +
Sbjct: 1058 SIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLK 1117
Query: 1570 LQESKQKDEDDEEE------------EDDDVDTML-IMQRLEAERRARDEERRR---QQQ 1613
L + K +D + + DV T + ++ +E+ D R +
Sbjct: 1118 LFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSE 1177
Query: 1614 LEEMRKREAEDRARQEEERRRQEEERTKRDAEE 1646
+E K+ E RA+Q+ ++RQ+++ ++ ++
Sbjct: 1178 AKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQ 1210
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 68.9 bits (167), Expect = 4e-11
Identities = 79/311 (25%), Positives = 132/311 (42%), Gaps = 31/311 (9%)
Query: 1349 IPATPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVA 1405
IP+ +VS P +L P P V G + +D P P L A+ A
Sbjct: 697 IPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAA 756
Query: 1406 AAE--------RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1457
E R KREE +R ++E R +EE R+++E+ERK R + A
Sbjct: 757 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK----RREEEELARRKQE 812
Query: 1458 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1517
A + + E+ L+R +E R+ Q + R ERR + +EEL W
Sbjct: 813 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 872
Query: 1518 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
R+ +E + ++ + + +E L+ EE +R RK LE Q QK L +Q+
Sbjct: 873 REEEEAQRRLEENRL--RMEEEAARLRH------EEEERKRK-ELEVQRQKELMRQRQQQ 923
Query: 1578 ED-----DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLE--EMRKREAEDRARQEE 1630
++ ++++ + M + +++ + Q L E++K E E + E
Sbjct: 924 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE 983
Query: 1631 ERRRQEEERTK 1641
E+RRQ+ E K
Sbjct: 984 EQRRQQRELMK 994
Score = 62.4 bits (150), Expect = 4e-09
Identities = 65/234 (27%), Positives = 112/234 (47%), Gaps = 24/234 (10%)
Query: 1416 QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE 1475
Q+ Y + A+ ++ +++Q+ L + Q+L ++ Q + P ++ P
Sbjct: 654 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMR----ISDQNIIPSVTRSVSVPDT 709
Query: 1476 TVIRELQPQ-QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1534
I ELQP QP E + + + D+ +P P A E+L++ ++
Sbjct: 710 GSIWELQPTASQPTVWEGGSVWDLPL--------DTTTPGP----ALEQLQQLEKAKAAK 757
Query: 1535 MLSKEIQELQSKPDRSAEESDRLRKLMLEWQ-FQKRLQESKQKDEDDEEEEDDDVDTMLI 1593
L +E +E + + R EE R +L + + +R QE ++K ++EE + L
Sbjct: 758 -LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 816
Query: 1594 MQRLE--AERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
QR + A RR R+EE R+QQ E R E+R R+EEERR+QEE K++ E
Sbjct: 817 RQREQEIALRRQREEEERQQQ---EEALRRLEERRREEEERRKQEELLRKQEEE 867
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/58 (44%), Positives = 38/58 (65%)
Query: 1592 LIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKVM 1649
L +R EAE RA+ EE R++Q E R++E R +QEEER+R+EEE R +E+ +
Sbjct: 758 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL 815
Score = 46.6 bits (109), Expect = 2e-04
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 9/83 (10%)
Query: 1568 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRAR 1627
++L+++K + E E + + + E E R R EE RRQQ+ E +R+++ E+R R
Sbjct: 748 QQLEKAKAAKLEQERREAE------MRAKREEEERKRQEELRRQQE-EILRRQQEEERKR 800
Query: 1628 QEEER--RRQEEERTKRDAEEKV 1648
+EEE RR++EE +R E+++
Sbjct: 801 REEEELARRKQEEALRRQREQEI 823
Score = 36.2 bits (82), Expect = 0.27
Identities = 24/121 (19%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Query: 139 KAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAL-RQASDKDDRPFQGEDVENSR 197
+A+ E++ +E + + + L +++++E+K+RE+E L R+ ++ R + +++ R
Sbjct: 768 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 827
Query: 198 LAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSL 257
E + E + R +RR+Q++L ++ +E + R + R+ + L
Sbjct: 828 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 887
Query: 258 K 258
+
Sbjct: 888 R 888
Score = 34.7 bits (78), Expect = 0.79
Identities = 62/273 (22%), Positives = 110/273 (40%), Gaps = 52/273 (19%)
Query: 1422 EKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK------PEKPS----TLQ 1471
E +LEEERER+ RE++R+ + + L A QQ K KPS +L
Sbjct: 969 EIQKLEEERERQLREEQRR----QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1024
Query: 1472 RPQETVIRELQPQQQPRTIERRD--LQYITVSKEELSSGDSL-------SPDPWKRDAKE 1522
Q+ R++Q QQQ + ++ + T S S G+S+ P+ W D
Sbjct: 1025 EIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVS 1084
Query: 1523 KL-----EKQQQMHIVDMLSKEIQELQSKP--------DRSAEESDRLRKLMLEWQFQKR 1569
+ K M D KE+ S +S S+R K + E + +
Sbjct: 1085 SIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLK 1144
Query: 1570 LQESKQKDEDDEEE------------EDDDVDTML-IMQRLEAERRARDEERRR---QQQ 1613
L + K +D + + DV T + ++ +E+ D R +
Sbjct: 1145 LFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSE 1204
Query: 1614 LEEMRKREAEDRARQEEERRRQEEERTKRDAEE 1646
+E K+ E RA+Q+ ++RQ+++ ++ ++
Sbjct: 1205 AKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQ 1237
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 68.9 bits (167), Expect = 4e-11
Identities = 79/311 (25%), Positives = 132/311 (42%), Gaps = 31/311 (9%)
Query: 1349 IPATPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVA 1405
IP+ +VS P +L P P V G + +D P P L A+ A
Sbjct: 676 IPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAA 735
Query: 1406 AAE--------RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1457
E R KREE +R ++E R +EE R+++E+ERK R + A
Sbjct: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK----RREEEELARRKQE 791
Query: 1458 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1517
A + + E+ L+R +E R+ Q + R ERR + +EEL W
Sbjct: 792 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 851
Query: 1518 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
R+ +E + ++ + + +E L+ EE +R RK LE Q QK L +Q+
Sbjct: 852 REEEEAQRRLEENRL--RMEEEAARLRH------EEEERKRK-ELEVQRQKELMRQRQQQ 902
Query: 1578 ED-----DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLE--EMRKREAEDRARQEE 1630
++ ++++ + M + +++ + Q L E++K E E + E
Sbjct: 903 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE 962
Query: 1631 ERRRQEEERTK 1641
E+RRQ+ E K
Sbjct: 963 EQRRQQRELMK 973
Score = 62.4 bits (150), Expect = 4e-09
Identities = 65/234 (27%), Positives = 112/234 (47%), Gaps = 24/234 (10%)
Query: 1416 QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE 1475
Q+ Y + A+ ++ +++Q+ L + Q+L ++ Q + P ++ P
Sbjct: 633 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMR----ISDQNIIPSVTRSVSVPDT 688
Query: 1476 TVIRELQPQ-QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1534
I ELQP QP E + + + D+ +P P A E+L++ ++
Sbjct: 689 GSIWELQPTASQPTVWEGGSVWDLPL--------DTTTPGP----ALEQLQQLEKAKAAK 736
Query: 1535 MLSKEIQELQSKPDRSAEESDRLRKLMLEWQ-FQKRLQESKQKDEDDEEEEDDDVDTMLI 1593
L +E +E + + R EE R +L + + +R QE ++K ++EE + L
Sbjct: 737 -LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
Query: 1594 MQRLE--AERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
QR + A RR R+EE R+QQ E R E+R R+EEERR+QEE K++ E
Sbjct: 796 RQREQEIALRRQREEEERQQQ---EEALRRLEERRREEEERRKQEELLRKQEEE 846
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/58 (44%), Positives = 38/58 (65%)
Query: 1592 LIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKVM 1649
L +R EAE RA+ EE R++Q E R++E R +QEEER+R+EEE R +E+ +
Sbjct: 737 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL 794
Score = 46.6 bits (109), Expect = 2e-04
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 9/83 (10%)
Query: 1568 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRAR 1627
++L+++K + E E + + + E E R R EE RRQQ+ E +R+++ E+R R
Sbjct: 727 QQLEKAKAAKLEQERREAE------MRAKREEEERKRQEELRRQQE-EILRRQQEEERKR 779
Query: 1628 QEEER--RRQEEERTKRDAEEKV 1648
+EEE RR++EE +R E+++
Sbjct: 780 REEEELARRKQEEALRRQREQEI 802
Score = 36.2 bits (82), Expect = 0.27
Identities = 24/121 (19%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Query: 139 KAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAL-RQASDKDDRPFQGEDVENSR 197
+A+ E++ +E + + + L +++++E+K+RE+E L R+ ++ R + +++ R
Sbjct: 747 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 806
Query: 198 LAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSL 257
E + E + R +RR+Q++L ++ +E + R + R+ + L
Sbjct: 807 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 866
Query: 258 K 258
+
Sbjct: 867 R 867
Score = 34.7 bits (78), Expect = 0.79
Identities = 62/273 (22%), Positives = 110/273 (40%), Gaps = 52/273 (19%)
Query: 1422 EKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK------PEKPS----TLQ 1471
E +LEEERER+ RE++R+ + + L A QQ K KPS +L
Sbjct: 948 EIQKLEEERERQLREEQRR----QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
Query: 1472 RPQETVIRELQPQQQPRTIERRD--LQYITVSKEELSSGDSL-------SPDPWKRDAKE 1522
Q+ R++Q QQQ + ++ + T S S G+S+ P+ W D
Sbjct: 1004 EIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVS 1063
Query: 1523 KL-----EKQQQMHIVDMLSKEIQELQSKP--------DRSAEESDRLRKLMLEWQFQKR 1569
+ K M D KE+ S +S S+R K + E + +
Sbjct: 1064 SIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLK 1123
Query: 1570 LQESKQKDEDDEEE------------EDDDVDTML-IMQRLEAERRARDEERRR---QQQ 1613
L + K +D + + DV T + ++ +E+ D R +
Sbjct: 1124 LFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSE 1183
Query: 1614 LEEMRKREAEDRARQEEERRRQEEERTKRDAEE 1646
+E K+ E RA+Q+ ++RQ+++ ++ ++
Sbjct: 1184 AKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQ 1216
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 68.9 bits (167), Expect = 4e-11
Identities = 79/311 (25%), Positives = 132/311 (42%), Gaps = 31/311 (9%)
Query: 1349 IPATPVAVSQPIRT---DLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVA 1405
IP+ +VS P +L P P V G + +D P P L A+ A
Sbjct: 676 IPSVTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAA 735
Query: 1406 AAE--------RRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPL 1457
E R KREE +R ++E R +EE R+++E+ERK R + A
Sbjct: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERK----RREEEELARRKQE 791
Query: 1458 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1517
A + + E+ L+R +E R+ Q + R ERR + +EEL W
Sbjct: 792 EALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWA 851
Query: 1518 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
R+ +E + ++ + + +E L+ EE +R RK LE Q QK L +Q+
Sbjct: 852 REEEEAQRRLEENRL--RMEEEAARLRH------EEEERKRK-ELEVQRQKELMRQRQQQ 902
Query: 1578 ED-----DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLE--EMRKREAEDRARQEE 1630
++ ++++ + M + +++ + Q L E++K E E + E
Sbjct: 903 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLRE 962
Query: 1631 ERRRQEEERTK 1641
E+RRQ+ E K
Sbjct: 963 EQRRQQRELMK 973
Score = 62.4 bits (150), Expect = 4e-09
Identities = 65/234 (27%), Positives = 112/234 (47%), Gaps = 24/234 (10%)
Query: 1416 QRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQE 1475
Q+ Y + A+ ++ +++Q+ L + Q+L ++ Q + P ++ P
Sbjct: 633 QQQYAQVLAQQQKAALSSQQQQQLALLLQQFQTLKMR----ISDQNIIPSVTRSVSVPDT 688
Query: 1476 TVIRELQPQ-QQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVD 1534
I ELQP QP E + + + D+ +P P A E+L++ ++
Sbjct: 689 GSIWELQPTASQPTVWEGGSVWDLPL--------DTTTPGP----ALEQLQQLEKAKAAK 736
Query: 1535 MLSKEIQELQSKPDRSAEESDRLRKLMLEWQ-FQKRLQESKQKDEDDEEEEDDDVDTMLI 1593
L +E +E + + R EE R +L + + +R QE ++K ++EE + L
Sbjct: 737 -LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
Query: 1594 MQRLE--AERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
QR + A RR R+EE R+QQ E R E+R R+EEERR+QEE K++ E
Sbjct: 796 RQREQEIALRRQREEEERQQQ---EEALRRLEERRREEEERRKQEELLRKQEEE 846
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/58 (44%), Positives = 38/58 (65%)
Query: 1592 LIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEKVM 1649
L +R EAE RA+ EE R++Q E R++E R +QEEER+R+EEE R +E+ +
Sbjct: 737 LEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL 794
Score = 46.6 bits (109), Expect = 2e-04
Identities = 28/83 (33%), Positives = 50/83 (60%), Gaps = 9/83 (10%)
Query: 1568 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRAR 1627
++L+++K + E E + + + E E R R EE RRQQ+ E +R+++ E+R R
Sbjct: 727 QQLEKAKAAKLEQERREAE------MRAKREEEERKRQEELRRQQE-EILRRQQEEERKR 779
Query: 1628 QEEER--RRQEEERTKRDAEEKV 1648
+EEE RR++EE +R E+++
Sbjct: 780 REEEELARRKQEEALRRQREQEI 802
Score = 36.2 bits (82), Expect = 0.27
Identities = 24/121 (19%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Query: 139 KAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEAL-RQASDKDDRPFQGEDVENSR 197
+A+ E++ +E + + + L +++++E+K+RE+E L R+ ++ R + +++ R
Sbjct: 747 RAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRR 806
Query: 198 LAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSL 257
E + E + R +RR+Q++L ++ +E + R + R+ + L
Sbjct: 807 QREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 866
Query: 258 K 258
+
Sbjct: 867 R 867
Score = 34.7 bits (78), Expect = 0.79
Identities = 62/273 (22%), Positives = 110/273 (40%), Gaps = 52/273 (19%)
Query: 1422 EKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMK------PEKPS----TLQ 1471
E +LEEERER+ RE++R+ + + L A QQ K KPS +L
Sbjct: 948 EIQKLEEERERQLREEQRR----QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLL 1003
Query: 1472 RPQETVIRELQPQQQPRTIERRD--LQYITVSKEELSSGDSL-------SPDPWKRDAKE 1522
Q+ R++Q QQQ + ++ + T S S G+S+ P+ W D
Sbjct: 1004 EIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVS 1063
Query: 1523 KL-----EKQQQMHIVDMLSKEIQELQSKP--------DRSAEESDRLRKLMLEWQFQKR 1569
+ K M D KE+ S +S S+R K + E + +
Sbjct: 1064 SIWSNADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQNKKVEEEEKLLK 1123
Query: 1570 LQESKQKDEDDEEE------------EDDDVDTML-IMQRLEAERRARDEERRR---QQQ 1613
L + K +D + + DV T + ++ +E+ D R +
Sbjct: 1124 LFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHDYIRAYLGDTSE 1183
Query: 1614 LEEMRKREAEDRARQEEERRRQEEERTKRDAEE 1646
+E K+ E RA+Q+ ++RQ+++ ++ ++
Sbjct: 1184 AKEFAKQFLERRAKQKANQQRQQQQLPQQQQQQ 1216
>gi|140972063 protein phosphatase 1, regulatory subunit 9B [Homo
sapiens]
Length = 817
Score = 68.6 bits (166), Expect = 5e-11
Identities = 68/213 (31%), Positives = 102/213 (47%), Gaps = 25/213 (11%)
Query: 891 EPFIPTDLIENVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPN 950
E F DL++ V+ ++ A S E +++ D + P+ PE G IP
Sbjct: 385 EDFSEADLVD--VSAYSGLGEDSAGSALEEDDEDDEEDGEPPYE-PESGCV-----EIP- 435
Query: 951 GLQEFLDPLCQRGFCRLIPHTRSPGTWTIYFEGADYESHL-----LRENTELAQPLRKEP 1005
GL E DP R I + +P + DY+ + + E R E
Sbjct: 436 GLSEEEDPAPSRK----IHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVER 491
Query: 1006 -EIITVTLKKQN-GMGLSIVAAKGAGQD----KLGIYVKSVVKGGAADVDGRLAAGDQLL 1059
E+ V L+K + G+G+SI+ GAG D KLGI+VK+V +GGAA DGR+ D L+
Sbjct: 492 LELFPVELEKDSEGLGISIIGM-GAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLV 550
Query: 1060 SVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQ 1092
VDG SLVG++Q AA ++ T V + ++
Sbjct: 551 EVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRE 583
Score = 35.8 bits (81), Expect = 0.35
Identities = 73/338 (21%), Positives = 117/338 (34%), Gaps = 27/338 (7%)
Query: 1280 REDKAYQLERHRIEAAMDRKSDSDMWINQSSS----LDSSTSSQEHLNHSSKSVTPASTL 1335
+E A +L R DRK D + N S+ LD+ S ++ S A +
Sbjct: 163 KEAAARRLLRQERAGLQDRKLDVVVRFNGSTEALDKLDADAVSPT-VSQLSAVFEKADSR 221
Query: 1336 T--KSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPS 1393
T GPG + VS+ R PPPPPPP +GD P P
Sbjct: 222 TGLHRGPGLPRAAGVPQVNSKLVSKRSRVFQPPPPPPPAP--SGDAPAEKERCPAGQQPP 279
Query: 1394 ANQIGLPSAQVAAAERRK----REEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSL 1449
+++ E RK E E E A E + + G +
Sbjct: 280 QHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTVATAA 339
Query: 1450 NPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTI-ERRDLQYITVSKEELSSG 1508
+PAP P AQ ++ + + P+ V P P + E + + ++S+
Sbjct: 340 SPAPEEP-KAQAAPEKEAAAVAPPERGVGNGRAPDVAPEEVDESKKEDFSEADLVDVSAY 398
Query: 1509 DSLSPD----PWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEW 1564
L D + D ++ E + + + EI L + D + RK+
Sbjct: 399 SGLGEDSAGSALEEDDEDDEEDGEPPYEPESGCVEIPGLSEEEDPAPS-----RKIHFS- 452
Query: 1565 QFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERR 1602
+Q +D + ++DVD M E E+R
Sbjct: 453 --TAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKR 488
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 68.2 bits (165), Expect = 6e-11
Identities = 83/374 (22%), Positives = 158/374 (42%), Gaps = 63/374 (16%)
Query: 1276 QEELREDKAYQLERHRIEAAMDRKSDSDMWINQSSSLDSSTSSQEHLNHSSKSVTPASTL 1335
Q++ ++DK + E+ + A +R + S S S+ L+ SK+ P+S
Sbjct: 413 QKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKA-RPSSPS 471
Query: 1336 TKSGPGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSAN 1395
T W PA+ P P P P H LPP P +
Sbjct: 472 TS-----WHRPAS-----------------PCPSPGPGH------------TLPPKPPS- 496
Query: 1396 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRR-EQERKLGQMRTQSLNPAPF 1454
P A+ + R R + + A E++ + KRR E++ + + +PAP
Sbjct: 497 ----PRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAP- 551
Query: 1455 SPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPD 1514
SP A K + P+ + P + + P P + + T +EE + L +
Sbjct: 552 SPTPAPPQKEQPPA--ETPTDAAVLTSPPAPAPPVTPSKPMAG-TTDREEATR---LLAE 605
Query: 1515 PWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESK 1574
+R A+E+ E+++Q + LQ++ D+ E R+ + + + +
Sbjct: 606 K-RRQAREQREREEQE----------RRLQAERDKRMREEQLAREAEARAEREAEARRRE 654
Query: 1575 QKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRR 1634
+++ ++ + + + L Q+ EAE R+R+E R Q+LE R++ + + ++ +ERR+
Sbjct: 655 EQEAREKAQAEQEEQERLQKQKEEAEARSREEAER--QRLE--REKHFQQQEQERQERRK 710
Query: 1635 QEEERTKRDAEEKV 1648
+ EE KR + +V
Sbjct: 711 RLEEIMKRTRKSEV 724
Score = 55.8 bits (133), Expect = 3e-07
Identities = 59/235 (25%), Positives = 95/235 (40%), Gaps = 38/235 (16%)
Query: 1347 AAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGLPSAQVAA 1406
+A PA+P P T PP PP D ++ P P PP PS +A
Sbjct: 539 SAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSP-PAPAPPVT-----PSKPMAG 592
Query: 1407 AERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1466
REE R +++ + E+RER+ EQER+L R + + +Q+ E
Sbjct: 593 T--TDREEATRLLAEKRRQAREQRERE--EQERRLQAERDKRMR--------EEQLAREA 640
Query: 1467 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1526
+ +R E RE Q ++ E+ + + + KEE + R+ E+
Sbjct: 641 EARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEAR--------SREEAERQRL 692
Query: 1527 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDE 1581
+++ H ++ QE Q + R E R RK + E+KQK + E
Sbjct: 693 EREKH----FQQQEQERQERRKRLEEIMKRTRK--------SEVSETKQKQDSKE 735
Score = 55.1 bits (131), Expect = 6e-07
Identities = 64/280 (22%), Positives = 118/280 (42%), Gaps = 61/280 (21%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQ-----ERKLGQMRTQSLNPA----P 1453
+ + +++++++ +R EKEK+ L ER K+R+ +L L+P P
Sbjct: 408 EASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARP 467
Query: 1454 FSPLTA--------------QQMKPEKPS---TLQRPQETVIRELQPQQQPRTIERRDLQ 1496
SP T+ + P+ PS T P+ V R+ + ++ P D
Sbjct: 468 SSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKS 527
Query: 1497 YI---TVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQE--------LQS 1545
+++E ++ S +P P +K+Q + + S
Sbjct: 528 QSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPS 587
Query: 1546 KPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARD 1605
KP + + +L+ E KR Q +Q++ +++E +RL+AER
Sbjct: 588 KPMAGTTDREEATRLLAE----KRRQAREQREREEQE------------RRLQAER---- 627
Query: 1606 EERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAE 1645
++R R++QL REAE RA +E E RR+EE+ + A+
Sbjct: 628 DKRMREEQLA----REAEARAEREAEARRREEQEAREKAQ 663
Score = 52.8 bits (125), Expect = 3e-06
Identities = 77/361 (21%), Positives = 136/361 (37%), Gaps = 85/361 (23%)
Query: 1340 PGRWKTPAAIPATPVAVSQPIRTDLPPPPPPPPVHYAGDFDGMSMDLPLPPPPSANQIGL 1399
P R AA+P P + S + L P VH P +
Sbjct: 349 PDRTHPSAAVPVCPRSASA---SPLTPCSVTRSVHRCA------------PAGERGERRK 393
Query: 1400 PSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTA 1459
P+A + A R+R E +KEK E E E+++ R+ + QSL +P + L+A
Sbjct: 394 PNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSA 453
Query: 1460 ---------QQMKPEKPS----------------------------TLQRPQETVIRELQ 1482
+ +P PS T P+ V R+ +
Sbjct: 454 STASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEE 513
Query: 1483 PQQQPRTI---ERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQ--------QMH 1531
++ P ++ + +++E ++ S +P P +K+Q
Sbjct: 514 AKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAV 573
Query: 1532 IVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTM 1591
+ + SKP + + +L+ E KR Q +Q++ +++E
Sbjct: 574 LTSPPAPAPPVTPSKPMAGTTDREEATRLLAE----KRRQAREQREREEQE--------- 620
Query: 1592 LIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERR------RQEEERTKRDAE 1645
+RL+AER R E + ++ E +REAE R R+E+E R ++E+ER ++ E
Sbjct: 621 ---RRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKE 677
Query: 1646 E 1646
E
Sbjct: 678 E 678
Score = 34.3 bits (77), Expect = 1.0
Identities = 46/193 (23%), Positives = 84/193 (43%), Gaps = 40/193 (20%)
Query: 1462 MKPEKPSTLQRPQETVIRELQPQQQ-------PRTIERRDLQYITVSKEELSSGDSLSPD 1514
++PE PS P+ +E P + P + RD + S + + S
Sbjct: 66 LEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDS 125
Query: 1515 PWKRDAKEKLEKQQQMHIVDMLSKEIQE-----LQSKPDRSAEESDRLRKLMLEWQFQKR 1569
P K++++K + H L+KE +E L +K E+ ++ + L +K+
Sbjct: 126 P---PTKQEVKKAGERH---KLAKERREERAKYLAAKKAVWLEKEEKAKALR-----EKQ 174
Query: 1570 LQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQE 1629
LQE +++ E+ QRL+AE+R E R++Q+LE + +E + A Q
Sbjct: 175 LQERRRRLEE---------------QRLKAEQRRAALEERQRQKLE--KNKERYEAAIQR 217
Query: 1630 EERRRQEEERTKR 1642
++ E R +R
Sbjct: 218 SVKKTWAEIRQQR 230
Score = 32.0 bits (71), Expect = 5.1
Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 9/58 (15%)
Query: 1597 LEAERRARDEERRRQQQLEEMRKREAEDRARQE------EERRRQEEERTKRDAEEKV 1648
LE E +A+ R++QL+E R+R E R + E EER+RQ+ E+ K E +
Sbjct: 161 LEKEEKAK---ALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAI 215
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 67.8 bits (164), Expect = 8e-11
Identities = 57/258 (22%), Positives = 135/258 (52%), Gaps = 27/258 (10%)
Query: 1396 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEEE-----RERKRREQERKLGQMRTQSLN 1450
Q+ QV E + RE+ + E+E E+E +E + REQE GQ+R Q
Sbjct: 95 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE---GQVREQE-- 149
Query: 1451 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS 1510
+ Q+ + + R QE +RE + Q + + + R+ Q + ++E G+
Sbjct: 150 ----GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-QEGQMGEQEGQMGEQ 204
Query: 1511 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL 1570
+ + +E+++KQ++ + ++ ++++ + ++ E+ ++++K E Q QK+
Sbjct: 205 ---EEQMGEQEEQMQKQEEQ-----MGEQEEQMRKQEEQMGEQEEQVQKQ--EEQVQKQE 254
Query: 1571 QESKQKDED--DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQ 1628
++ ++++E ++EE+ + + ++ Q+ + E+ + E+ Q + +E + RE E++ R+
Sbjct: 255 EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE 314
Query: 1629 EEERRRQEEERTKRDAEE 1646
+EE+ R++EE+ + E+
Sbjct: 315 QEEQMREQEEQMGKQEEQ 332
Score = 67.4 bits (163), Expect = 1e-10
Identities = 62/258 (24%), Positives = 131/258 (50%), Gaps = 38/258 (14%)
Query: 1396 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFS 1455
Q+G Q+ E + E+ ++ ++E+ E+E + R+QE ++G+ Q
Sbjct: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM--RKQEEQMGEQEEQ-------- 242
Query: 1456 PLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDP 1515
+ Q+ + +K R QE +RE ++Q R E + L+ +++E +G+ +
Sbjct: 243 -VQKQEEQVQKQEEQMRKQEEQMRE--QEEQMREQEEQMLKQKEQTEQEEQTGEQ---EE 296
Query: 1516 WKRDAKEKL-EKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESK 1574
R+ +E++ E+++QM + +E +E K + E E ++++ Q K
Sbjct: 297 QMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK-------EQMWEQKEQMWK 349
Query: 1575 QKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEE--ER 1632
Q+++ E+EE MQ+ E + R ++E+ R+Q+ E+MRK+E + R ++E+ E+
Sbjct: 350 QEEQMGEQEEQ--------MQKQEEQVRKQEEQMRKQE--EQMRKQEEQMRKQEEQMGEQ 399
Query: 1633 RRQ--EEERTKRDAEEKV 1648
+ Q E++ R+ EE++
Sbjct: 400 KEQMGEQKEQMREQEEQM 417
Score = 65.5 bits (158), Expect = 4e-10
Identities = 53/255 (20%), Positives = 127/255 (49%), Gaps = 15/255 (5%)
Query: 1396 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEEE-----RERKRREQERKLGQMRTQSLN 1450
Q+ QV E + RE+ + E+E E+E +E + EQE ++G+ Q
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGE 210
Query: 1451 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS 1510
+QM ++ ++ ++ +E Q Q+Q +++++ Q + K+E +
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ---MRKQEEQMREQ 267
Query: 1511 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRL 1570
+ + ++ L++++Q + ++ ++++ + ++ E+ +++R E + Q R
Sbjct: 268 --EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMR----EQEEQMRE 321
Query: 1571 QESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEE 1630
QE + ++++ E + Q + E + ++E + Q+Q E++RK+E + R +QEE
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR-KQEE 380
Query: 1631 ERRRQEEERTKRDAE 1645
+ R+QEE+ K++ +
Sbjct: 381 QMRKQEEQMRKQEEQ 395
Score = 64.7 bits (156), Expect = 7e-10
Identities = 55/258 (21%), Positives = 129/258 (50%), Gaps = 21/258 (8%)
Query: 1396 QIGLPSAQVAAAERRKREEHQRWYEKEKARLEEE-----RERKRREQERKLGQMRTQSLN 1450
Q+ QV E + RE+ + E+E E+E +E + REQE ++G+ Q
Sbjct: 144 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE 203
Query: 1451 PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDS 1510
+QM+ ++ ++ ++ +E Q +Q +++++ Q V K+E
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQ---VQKQE------ 254
Query: 1511 LSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKL---MLEWQFQ 1567
+ ++ ++ E+++QM + + +E + +++ E+ +++R+ M E + Q
Sbjct: 255 ---EQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQ 311
Query: 1568 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRAR 1627
R QE + ++++++ + ++ Q E + + +E + +Q E+M+K+E + R +
Sbjct: 312 MREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVR-K 370
Query: 1628 QEEERRRQEEERTKRDAE 1645
QEE+ R+QEE+ K++ +
Sbjct: 371 QEEQMRKQEEQMRKQEEQ 388
Score = 60.5 bits (145), Expect = 1e-08
Identities = 51/238 (21%), Positives = 113/238 (47%), Gaps = 36/238 (15%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLG--------QMRTQSLNPAPFSPLTA 1459
E+ +++E Q ++E+ + +EE+ +K+ EQ RK QMR Q T
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286
Query: 1460 QQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRD 1519
Q+ + + R QE +RE + Q + + + R+ + +EE W++
Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEE---------QMWEQK 337
Query: 1520 AKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDED 1579
+ +K+Q + + ++ +++Q + ++ ++ +++RK E Q +K+ ++ ++++E
Sbjct: 338 EQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ--EEQMRKQEEQMRKQEEQ 395
Query: 1580 DEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEE 1637
E+++ Q E + + R++E + +Q E+MRK QEE Q+E
Sbjct: 396 MGEQKE---------QMGEQKEQMREQEEQMGEQKEQMRK--------QEEHMGEQKE 436
Score = 54.3 bits (129), Expect = 1e-06
Identities = 60/283 (21%), Positives = 133/283 (46%), Gaps = 34/283 (12%)
Query: 1390 PPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEE-----RERKRREQERKL--- 1441
P P Q+ QV E + RE+ + E+E E+E +E + REQE ++
Sbjct: 47 PLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 106
Query: 1442 -GQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITV 1500
GQ+R Q + Q+ + + R QE +RE + Q + + + R+ Q V
Sbjct: 107 EGQVREQE------GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-QEGQV 159
Query: 1501 SKEELSSGDSLSPDPWKRDAKEKLEKQ--QQMHIVDMLSKEIQELQSKPDRSAEESDRLR 1558
++E G + R+ + ++ +Q Q + ++ ++ + ++ E+ ++++
Sbjct: 160 REQE---GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ 216
Query: 1559 KL---MLEWQFQKRLQESKQKDEDDE-EEEDDDVDTMLIMQRLEAERRARDEERRRQQQL 1614
K M E + Q R QE + +++++ +++++ V R + E+ EE+ R+Q+
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEE 276
Query: 1615 EEMRKREAEDRARQ---------EEERRRQEEERTKRDAEEKV 1648
+ ++++E ++ Q E+E + +E+E R+ EE++
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQM 319
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 67.4 bits (163), Expect = 1e-10
Identities = 68/282 (24%), Positives = 129/282 (45%), Gaps = 48/282 (17%)
Query: 1404 VAAAERRKREEHQRWYEKEKARLEEERER------KRREQERKLGQMRTQSLNPAPFSPL 1457
V A + R+EHQR + + +EE +ER +R ++E + + Q + A L
Sbjct: 554 VTAYLKNSRKEHQRILARRQT-IEERKERLESLNIQREKEELEQREAELQKVRKAEEERL 612
Query: 1458 TAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWK 1517
+ + EK LQ ++ I++ +++ I++ +L ++ + L PD
Sbjct: 613 RQEAKEREKERILQEHEQ--IKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIM 670
Query: 1518 RDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
E+LEK++ KE+QE ++ + +R ++L + +E + KD
Sbjct: 671 AKQVEQLEKEK---------KELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKD 721
Query: 1578 EDD-EEEEDDDVDTM----------------------LIMQRLEAERRARDEERRRQ--Q 1612
D E++E++ + TM L + RL+A R++ EE+ +Q +
Sbjct: 722 MDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEE 781
Query: 1613 QLEEMRKREAEDRARQEEERRR-----QEEERTKRDAEEKVM 1649
+L E R E+R RQ +E RR ++EE +R AEE+++
Sbjct: 782 RLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQML 823
Score = 65.1 bits (157), Expect = 5e-10
Identities = 69/284 (24%), Positives = 133/284 (46%), Gaps = 41/284 (14%)
Query: 1399 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1458
L + A ER ++E +R EKE+ E E+ +K+ +ER L Q++ L F +
Sbjct: 601 LQKVRKAEEERLRQEAKER--EKERILQEHEQIKKKTVRER-LEQIKKTELGAKAFKDID 657
Query: 1459 AQQMKPEKPSTLQRPQ----ETVIRELQP--QQQPRTIE----RRDLQYITVSKEELSSG 1508
+ ++ P + Q E +ELQ + Q + I+ + L+ I + K
Sbjct: 658 IEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQ 717
Query: 1509 DSLSPDPWKRDAKEK-----LEKQQQMHIVDMLSKEIQE-----LQSKPDRSAEESDRLR 1558
D W++ +E+ LE+++ + + +S+ +++ ++ K R + ++L+
Sbjct: 718 RIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLK 777
Query: 1559 KL--MLEWQFQKRLQESKQKDEDD---------EEEEDDDVDTMLIMQRLE---AERRAR 1604
+ L + RL+E K++ +++ EEEE + ++ +R E AER R
Sbjct: 778 QFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKR 837
Query: 1605 DEERRRQQQ----LEEMRKREAEDRARQEEERRRQEEERTKRDA 1644
+EE R Q+ LEE+ +++ + EE RR+EEER D+
Sbjct: 838 EEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDS 881
Score = 45.1 bits (105), Expect = 6e-04
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 23/149 (15%)
Query: 1508 GDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQ 1567
GD P PW+ K ++++ K +E P S +R EW +
Sbjct: 1161 GDDSRPGPWRPLVKPGGWREKE--------KAREESWGPPRESRPSEER------EWDRE 1206
Query: 1568 KRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRK-------- 1619
K Q E+++++ + + D + R + RR RDE R+ EE
Sbjct: 1207 KERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRD 1266
Query: 1620 -REAEDRARQEEERRRQEEERTKRDAEEK 1647
R+ +DR R+ ++RR E R RD ++
Sbjct: 1267 DRDRDDRRRERDDRRDLRERRDLRDDRDR 1295
Score = 37.0 bits (84), Expect = 0.16
Identities = 24/117 (20%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 125 RFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQASDKD 184
R ++ + + Q E +++E +Q ++ ++ ++E K+REKE + Q ++
Sbjct: 572 RQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHEQI 631
Query: 185 DRPF---QGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFR 238
+ + E ++ + L A+ +KD+ +P+ +M ++ +Q LEK +E +
Sbjct: 632 KKKTVRERLEQIKKTELGAKAFKDIDIEDLEEL--DPDFIMAKQVEQ-LEKEKKELQ 685
Score = 35.8 bits (81), Expect = 0.35
Identities = 58/237 (24%), Positives = 94/237 (39%), Gaps = 50/237 (21%)
Query: 1418 WYEKEKARLE-----------EERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1466
W EKEKAR E EERE R ++ + Q R ++ PE+
Sbjct: 1178 WREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREEN------------DKDPER 1225
Query: 1467 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1526
+R + R +P+ + RR ++E S DS D RD + + E+
Sbjct: 1226 ERDRERDVDREDRFRRPRDEGGW--RRG-----PAEESSSWRDSSRRDDRDRDDRRR-ER 1277
Query: 1527 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1586
+ + +E ++L+ DR R+ + W +R + K DD EE D
Sbjct: 1278 DDRRDL-----RERRDLRDDRDRRGPPLRSEREEVSSW---RRADDRK----DDRVEERD 1325
Query: 1587 DVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRD 1643
+R+ +RD ER R ++ E K +A RA ++ E R+ + T D
Sbjct: 1326 PP------RRVPPPALSRDRERDRDRE-REGEKEKASWRAEKDRESLRRTKNETDED 1375
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 67.4 bits (163), Expect = 1e-10
Identities = 74/287 (25%), Positives = 120/287 (41%), Gaps = 33/287 (11%)
Query: 906 AENTADELARSDGREV------QLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPL 959
A +E S G EV +LE PD +L +G+ + N P+ L+E P
Sbjct: 227 ANKAPEESKGSAGCEVSSDPSTELENGPDPELG-----NGHVFQL-ENGPDSLKEVAGPH 280
Query: 960 CQR-----GFCRLIPHTRSPGTWTI----YFEGA--DYESHLLRENTELAQPLRKEPEII 1008
+R G IP T +P T + + +G D++S E+ + + E
Sbjct: 281 LERSEVDRGTEHRIPKTDAPLTTSNDKRRFSKGGKTDFQSSDCLAREEVGRIWKME---- 336
Query: 1009 TVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVG 1068
LK+ +G+G+ + +G+ + I V V +GGAA DGRL+ GD+LL ++G LVG
Sbjct: 337 --LLKESDGLGIQVSGGRGSKRSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVG 394
Query: 1069 LSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEG 1128
LS E A ++ + +V L VA + L L ++ P + + S E
Sbjct: 395 LSHEEAVAILRSATGMVQLVVASKENSAEDLLRLTSKSLPDLTSSVEDVSSWTDNEDQEA 454
Query: 1129 FELYNNSTQNGSPESPQLPWAEYSEPKKLPGDDRLMKNRADHRSSPN 1175
+ G+ S Q EP+ + G + N + N
Sbjct: 455 ----DGEEDEGTSSSVQRAMPGTDEPQDVCGAEESKGNLESPKQGSN 497
Score = 52.8 bits (125), Expect = 3e-06
Identities = 30/101 (29%), Positives = 55/101 (54%), Gaps = 10/101 (9%)
Query: 984 ADYESHLLRENTELAQPLRKE-------PEIITVT---LKKQNGMGLSIVAAKGAGQDKL 1033
A E H+++++T + E P +I++ +K G+G SI + + ++
Sbjct: 553 ASQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQM 612
Query: 1034 GIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERA 1074
GI+VK++ G+A DGRL GD++L V+G + GL+ + A
Sbjct: 613 GIFVKTIFPNGSAAEDGRLKEGDEILDVNGIPIKGLTFQEA 653
Score = 48.9 bits (115), Expect = 4e-05
Identities = 26/67 (38%), Positives = 40/67 (59%)
Query: 1012 LKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQ 1071
LK G+GLS+ K + + +K V KGGAA+ G + AGD++L+++G+ LVGL
Sbjct: 2754 LKTSAGLGLSLDGGKSSVTGDGPLVIKRVYKGGAAEQAGIIEAGDEILAINGKPLVGLMH 2813
Query: 1072 ERAAELM 1078
A +M
Sbjct: 2814 FDAWNIM 2820
Score = 45.8 bits (107), Expect = 3e-04
Identities = 25/75 (33%), Positives = 38/75 (50%)
Query: 1004 EPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDG 1063
E ++ + L ++ G GL A G + I V V GAA +G + GD LLSV+G
Sbjct: 2617 EEDVCFIVLNRKEGSGLGFSVAGGTDVEPKSITVHRVFSQGAASQEGTMNRGDFLLSVNG 2676
Query: 1064 RSLVGLSQERAAELM 1078
SL GL+ +++
Sbjct: 2677 ASLAGLAHGNVLKVL 2691
Score = 37.7 bits (86), Expect = 0.093
Identities = 23/64 (35%), Positives = 37/64 (57%), Gaps = 1/64 (1%)
Query: 1000 PLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKL-GIYVKSVVKGGAADVDGRLAAGDQL 1058
P K+ ++ VTL K+ +GL I A A ++ GIY+ S+ G A ++ L+ GDQ+
Sbjct: 719 PGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQI 778
Query: 1059 LSVD 1062
L V+
Sbjct: 779 LEVN 782
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 66.6 bits (161), Expect = 2e-10
Identities = 61/253 (24%), Positives = 119/253 (47%), Gaps = 43/253 (16%)
Query: 1411 KREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTL 1470
K + W + E+ + E++ + + E++ K G + + + M EK T
Sbjct: 170 KSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQV----------EVMVEEK--TT 217
Query: 1471 QRPQETVIRELQPQQ----QPRTIERRDLQYITVSKEELSSGDSLSPDPWKR-----DAK 1521
+ +ETV+ L+ Q +P+ E R+ +S E + +R + +
Sbjct: 218 ESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEER 277
Query: 1522 EKLEKQQQMHIVD----MLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKD 1577
E+++ +Q I D + ++E Q + R AEE +R+R + +KR E +Q+
Sbjct: 278 ERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR------EEEKRAAEERQRI 331
Query: 1578 EDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDRAR---QEEERRR 1634
+++E+ ++ QR++ E + EER+R ++E KR AE+R R +EEE+ +
Sbjct: 332 KEEEKRAAEE------RQRIKEEEKRAAEERQR---IKEEEKRAAEERQRARAEEEEKAK 382
Query: 1635 QEEERTKRDAEEK 1647
EE++ + EEK
Sbjct: 383 VEEQKRNKQLEEK 395
Score = 63.9 bits (154), Expect = 1e-09
Identities = 73/273 (26%), Positives = 123/273 (45%), Gaps = 32/273 (11%)
Query: 1403 QVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLG---QMRTQSLNPAPFSPLTA 1459
++ E+R EE QR E+EK R EER+R R E+E K Q R + L + +
Sbjct: 344 RIKEEEKRAAEERQRIKEEEK-RAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHA-MQE 401
Query: 1460 QQMKPEKPSTL--------QRPQE----TVIRELQPQQQPRTIE--RRDLQYI--TVSKE 1503
++K EK ++ QE T + + Q +++ ++ R LQ T KE
Sbjct: 402 TKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKE 461
Query: 1504 ELSSGDSLSPDPWKRDAKEKLE--------KQQQMHIVDMLSKEIQELQSKPDRSAEESD 1555
E+ K + K ++ K Q + K + S+P A
Sbjct: 462 EIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDT 521
Query: 1556 RLRKLMLEWQFQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAE--RRARDEERRRQQQ 1613
+ + + + KRL+E +++ + E EE + + LE E ++ R+E R+ ++
Sbjct: 522 KEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEE 581
Query: 1614 LEEMRKREAEDRA-RQEEERRRQEEERTKRDAE 1645
E+ RK+E DR R+EEE+RR +EE +R AE
Sbjct: 582 EEQRRKQEEADRKLREEEEKRRLKEEIERRRAE 614
Score = 55.8 bits (133), Expect = 3e-07
Identities = 55/234 (23%), Positives = 111/234 (47%), Gaps = 17/234 (7%)
Query: 1422 EKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIREL 1481
E+ EER +KR ++ + + ++ A S L +++M+ + ET +E
Sbjct: 98 ERLARREERRQKRLQEALERQKEFDPTITDASLS-LPSRRMQNDTAEN-----ETTEKEE 151
Query: 1482 QPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQ 1541
+ + + E + + +T S ++ D + K++ KEK E++++ + +
Sbjct: 152 KSESRQERYEIEETETVTKSYQK---NDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQV 208
Query: 1542 EL--QSKPDRSAEESD--RLRKLMLEWQFQKRLQESKQKDED----DEEEEDDDVDTMLI 1593
E+ + K S EE+ L+ + + K+ +E +Q ++ ++ EE+D
Sbjct: 209 EVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAE 268
Query: 1594 MQRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1647
RLEAE R R + + ++ +E + EAE++A +E RR+ EER + EEK
Sbjct: 269 RARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEK 322
Score = 53.1 bits (126), Expect = 2e-06
Identities = 62/260 (23%), Positives = 124/260 (47%), Gaps = 45/260 (17%)
Query: 1401 SAQVAAAERRKREEHQRWYEKEKARLE-EERERKRREQERKLGQMRTQSLNPAPFSPLTA 1459
S +++ E+ + E+ +R E E+ARLE EERER + EQ++K+ R A
Sbjct: 248 SDEISHHEKMEEEDKER-AEAERARLEAEERERIKAEQDKKIADER-------------A 293
Query: 1460 QQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRD 1519
+ EK + +R + RE + +++ R E+R + KEE KR
Sbjct: 294 RIEAEEKAAAQERER----REAEERERMREEEKRAAEERQRIKEEE-----------KRA 338
Query: 1520 AKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDED 1579
A+E+ +++ ++E Q ++ + R+AEE R R E + + +KQ +E
Sbjct: 339 AEERQRIKEEEK---RAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEK 395
Query: 1580 DEEEEDDDVDTMLIMQRLEA----ERRARDEERR----RQQQLEEMRKREAEDRARQEE- 1630
++ + + Q++E E++A++++ + ++Q E+ K +A+ QE+
Sbjct: 396 KHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDK 455
Query: 1631 ---ERRRQEEERTKRDAEEK 1647
++ ++E+ K+D E K
Sbjct: 456 PTFKKEEIKDEKIKKDKEPK 475
Score = 52.0 bits (123), Expect = 5e-06
Identities = 64/290 (22%), Positives = 123/290 (42%), Gaps = 50/290 (17%)
Query: 1407 AERRKREEHQRWYEKEKARLEEERERKRREQERKLGQ------MRTQSLNPAPFSPLTAQ 1460
A +R ++ + + + R +ER R+++E+E LGQ + Q+ P + T
Sbjct: 26 AYQRNDDDEEEAARERRRRARQERLRQKQEEE-SLGQVTDQVEVNAQNSVPDEEAKTTTT 84
Query: 1461 QMKPEKPSTLQRPQETVIRELQPQQQ-PRTIERRDLQYITVSKEELS-SGDSLSPDPWKR 1518
+ E + RE + Q++ +ER+ T++ LS + D +
Sbjct: 85 NTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAEN 144
Query: 1519 DAKEKLEKQQ------QMHIVDMLSKEIQ-------ELQSKPDRSAEESDR-------LR 1558
+ EK EK + ++ + ++K Q E K D+ EE + +
Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIG 204
Query: 1559 KLMLEWQFQKRLQESKQ-----------------KDEDDEEEEDDDVDTMLIMQRLEAER 1601
+ +E +++ ES++ K E++ E+ D++ M+ + ER
Sbjct: 205 ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264
Query: 1602 ----RARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1647
RAR E R++ E K+ A++RAR E E + +ER +R+AEE+
Sbjct: 265 AEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Score = 50.1 bits (118), Expect = 2e-05
Identities = 70/312 (22%), Positives = 139/312 (44%), Gaps = 68/312 (21%)
Query: 1399 LPSAQVAAAERRKR---EEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFS 1455
+ + + AAA+ R+R EE +R E+EK R EER+R +E+E++ + R + +
Sbjct: 295 IEAEEKAAAQERERREAEERERMREEEK-RAAEERQR-IKEEEKRAAEERQRIKEEEKRA 352
Query: 1456 PLTAQQMKPEKPSTLQ-----RPQETVIRELQPQQQPRTIERRD--LQYITVSKEELSSG 1508
Q++K E+ + R +E +++ Q++ + +E + +Q + E++
Sbjct: 353 AEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKV--- 409
Query: 1509 DSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQK 1568
+ W + K + +K Q + ++ ++Q+K ++ E+ +K ++ + K
Sbjct: 410 EQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIK 469
Query: 1569 RLQESKQ---------------KDEDDE-----------------------EEEDDDVDT 1590
+ +E K+ K ++ E +E +
Sbjct: 470 KDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQ 529
Query: 1591 MLIMQRLEAERRARDE------ERRRQQQ------LEEMRKREAEDR--ARQEEERRRQE 1636
+ +RLE RR R E E+ +Q+Q LEE++K+ E R +EE+RR+QE
Sbjct: 530 VEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQE 589
Query: 1637 E-ERTKRDAEEK 1647
E +R R+ EEK
Sbjct: 590 EADRKLREEEEK 601
Score = 45.4 bits (106), Expect = 4e-04
Identities = 61/279 (21%), Positives = 118/279 (42%), Gaps = 68/279 (24%)
Query: 1403 QVAAAERRKREEHQRWY--EKEKARLEEERERKRRE------QERKL-GQMRTQSLNPAP 1453
++ E+R EE QR E+EKA++EE++ K+ E QE K+ G+ Q +
Sbjct: 358 RIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKW 417
Query: 1454 FSPLTAQQMK----------PEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKE 1503
+ AQ+ K EK + +Q +E ++E +P + I+ ++ KE
Sbjct: 418 VNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREK-LQEDKPTFKKEEIKDEKIKKDKEPKE 476
Query: 1504 ELSS---------------------------------GDSLSPDPWKRDAKEKLEKQQQM 1530
E+ S G S D + + ++E +++
Sbjct: 477 EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRL 536
Query: 1531 HIV-----DMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEED 1585
+ + S+E ++L+ K +A E + L+K KR + K +E+++ +
Sbjct: 537 EELRRRRGETESEEFEKLKQKQQEAALELEELKK--------KREERRKVLEEEEQRRKQ 588
Query: 1586 DDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAED 1624
++ D L + E +RR ++E RR+ + E R++ ED
Sbjct: 589 EEADRKL--REEEEKRRLKEEIERRRAEAAEKRQKMPED 625
Score = 34.7 bits (78), Expect = 0.79
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 19/73 (26%)
Query: 1566 FQKRLQESKQKDEDDEEEEDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRKREAEDR 1625
F++R + +QK E+ RLEAER A +R EE RE R
Sbjct: 4 FERRRELRRQKREE---------------MRLEAERIAY----QRNDDDEEEAARERRRR 44
Query: 1626 ARQEEERRRQEEE 1638
ARQE R++QEEE
Sbjct: 45 ARQERLRQKQEEE 57
Score = 33.1 bits (74), Expect = 2.3
Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Query: 1408 ERRKREEHQRWY--EKEKARLEEERERKRREQERKLGQMRTQSLN 1450
+RRK+EE R E+EK RL+EE ER+R E K +M L+
Sbjct: 584 QRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLS 628
Score = 32.0 bits (71), Expect = 5.1
Identities = 17/53 (32%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Query: 1595 QRLEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTKRDAEEK 1647
+R E R+ R+E R +++ R + E+ A +E RRR +ER ++ EE+
Sbjct: 6 RRRELRRQKREEMRLEAERIAYQRNDDDEEEAARER-RRRARQERLRQKQEEE 57
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 65.9 bits (159), Expect = 3e-10
Identities = 64/240 (26%), Positives = 110/240 (45%), Gaps = 43/240 (17%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLTAQQMKPEKP 1467
E+ K+E+ ++ EKE+ E ERER+R +ER+ + R + + EK
Sbjct: 294 EKGKKEKERQEIEKERRERERERERERERRERERERER---------------EREREKE 338
Query: 1468 STLQRPQETVIRELQPQQQPRTIER---RDLQYITVSKEELSSGDSLSPDPWKRDAKEKL 1524
+R +E + + + RT ER RD + E SS + +D
Sbjct: 339 KERERERE------RDRDRDRTKERDRDRDRERDRDRDRERSSDRN-------KDRSRSR 385
Query: 1525 EKQQQMHIVDMLSKEIQELQSKPDRSAE-ESDRLRKLMLEWQFQKRLQESKQKDEDDEEE 1583
EK + +E + + +R E E +R R+ E + ++ + K K D EE+
Sbjct: 386 EKSRDRE---------REREREREREREREREREREREREREREREREREKDKKRDREED 436
Query: 1584 EDDDVDTMLIMQRLEAERRARDEERRRQQQLEEMRK-REAEDRARQEEERRRQEEERTKR 1642
E+D + + ++L E+ A +ER + ++ E +K RE E A +EEERRR+ + KR
Sbjct: 437 EEDAYERRKLERKLR-EKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495
Score = 64.7 bits (156), Expect = 7e-10
Identities = 59/246 (23%), Positives = 120/246 (48%), Gaps = 35/246 (14%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKR-REQERKLGQMRTQSLNPAPFSPLTAQQMKPEK 1466
ER + E +R E+E+ R E ERER+R RE+ER+ + R + + E+
Sbjct: 394 ERERERERERERERERER-EREREREREREREREKDKKRDRE--------------EDEE 438
Query: 1467 PSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKRDAKEKLEK 1526
+ +R E +RE + Q R ++ +++ ++E ++++A+ + E+
Sbjct: 439 DAYERRKLERKLREKEAAYQER-LKNWEIRERKKTRE------------YEKEAEREEER 485
Query: 1527 QQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDEDDEEEEDD 1586
+++M KE E DR + R L + +++ E+ ++D E+EE +
Sbjct: 486 RREMAKEAKRLKEFLE-DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELE 544
Query: 1587 DVDTMLIMQR-----LEAERRARDEERRRQQQLEEMRKREAEDRARQEEERRRQEEERTK 1641
++ L+ + E +R ++ ERRRQ Q+++ + E E+ +QE+E +R+E +
Sbjct: 545 EIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE 604
Query: 1642 RDAEEK 1647
+ E+K
Sbjct: 605 EEPEQK 610
Score = 60.8 bits (146), Expect = 1e-08
Identities = 75/281 (26%), Positives = 128/281 (45%), Gaps = 49/281 (17%)
Query: 1408 ERRKREEHQRWYEKEKARLEEERERKR-------------REQERKLGQMRTQSLNPAPF 1454
ER + E +R EKEK R E ERER R RE++R + R+ N
Sbjct: 324 EREREREREREREKEKER-ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNK--- 379
Query: 1455 SPLTAQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPD 1514
+++ ++ +R +E + +++ R ER + K++ + D
Sbjct: 380 DRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEED 439
Query: 1515 PWKRDAKE-KLEKQQQMHIVDMLSKEIQELQSKPDRSAE---ESDRLRKLMLEWQFQKRL 1570
++R E KL +++ + + + EI+E + + E E +R R++ E KRL
Sbjct: 440 AYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKE---AKRL 496
Query: 1571 QESKQKDEDDEEEEDDDVDTMLIMQRL---EAERRARDEERRRQ-QQLEEMRKR------ 1620
+E + D DD+ ++ + +RL E E A + +R+R+ ++LEE+R+R
Sbjct: 497 KEFLE-DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGH 555
Query: 1621 ---EAE-DRARQEEERRRQ----------EEERTKRDAEEK 1647
+AE R QE ERRRQ EEE K++ EEK
Sbjct: 556 PDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEK 596
Score = 58.9 bits (141), Expect = 4e-08
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 37/247 (14%)
Query: 1429 ERERKRREQERK-----LGQMRTQSLN-PAPFSPLTAQQMKPEKPSTLQRPQETVIRELQ 1482
+ E KRR+Q K L + + LN P+ S ++ K EK + R + L
Sbjct: 197 DEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFR--RFPVAPLI 254
Query: 1483 PQQQPRTIERRDLQYITVSKEE---LSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKE 1539
P I + D+ I + +++ +S S D K+ +EK +K+++ ++ KE
Sbjct: 255 PYP---LITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIE---KE 308
Query: 1540 IQELQSKPDRSAEESDRLRKLMLEWQFQKRLQE------------SKQKDEDDEEEEDDD 1587
+E + + +R E +R R+ E + +K + +K++D D + E D D
Sbjct: 309 RRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRD 368
Query: 1588 VDTMLIMQRLEAERRARDE--------ERRRQQQLEEMRKREAEDRARQEEERRRQEEER 1639
D R + R+R++ ER R+++ E R+RE E +E ER R+ E+
Sbjct: 369 RDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKD 428
Query: 1640 TKRDAEE 1646
KRD EE
Sbjct: 429 KKRDREE 435
Score = 34.3 bits (77), Expect = 1.0
Identities = 38/188 (20%), Positives = 78/188 (41%), Gaps = 31/188 (16%)
Query: 1399 LPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERKLGQMRTQSLNPAPFSPLT 1458
L + A ER K E + + + E ERE +RR + K + + L
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDD--- 506
Query: 1459 AQQMKPEKPSTLQRPQETVIRELQPQQQPRTIERRDLQYITVSKEELSSGDSLSPDPWKR 1518
K + S LQ+ +E++ ++ R E+ +L+ I ++ L + PD +
Sbjct: 507 RDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEI---RQRLLAEGHPDPDAELQ 563
Query: 1519 DAKEKLEKQQQMHIVDMLSKEIQELQSKPDRSAEESDRLRKLMLEWQFQKRLQESKQKDE 1578
+++ E+++Q +++ +P+ EE ++ QE ++K E
Sbjct: 564 RMEQEAERRRQ-----------PQIKQEPESEEEEEEK--------------QEKEEKRE 598
Query: 1579 DDEEEEDD 1586
+ EEE++
Sbjct: 599 EPMEEEEE 606
Score = 31.6 bits (70), Expect = 6.7
Identities = 22/115 (19%), Positives = 52/115 (45%), Gaps = 2/115 (1%)
Query: 121 DREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQA 180
DR+ D ++ + ++E+E + + ++E++ +++RE+E R+
Sbjct: 368 DRDRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREK 427
Query: 181 SDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQ 235
K DR ED R ++ E ++ + N E + +R++ ++ EK +
Sbjct: 428 DKKRDREEDEEDAYERRKLERKLRE-KEAAYQERLKNWE-IRERKKTREYEKEAE 480
>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
isoform 4 [Homo sapiens]
Length = 2490
Score = 65.9 bits (159), Expect = 3e-10
Identities = 37/90 (41%), Positives = 54/90 (60%), Gaps = 2/90 (2%)
Query: 1004 EPEIITVTLKK--QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSV 1061
E EI V LKK + G+G I+ + G+ LGI++ SV GG AD+DG L GD+L+SV
Sbjct: 1088 EREITLVNLKKDAKYGLGFQIIGGEKMGRLDLGIFISSVAPGGPADLDGCLKPGDRLISV 1147
Query: 1062 DGRSLVGLSQERAAELMTRTSSVVTLEVAK 1091
+ SL G+S A E++ VTL +++
Sbjct: 1148 NSVSLEGVSHHAAIEILQNAPEDVTLVISQ 1177
Score = 57.8 bits (138), Expect = 9e-08
Identities = 37/95 (38%), Positives = 55/95 (57%), Gaps = 6/95 (6%)
Query: 1003 KEPEIITVTL-KKQNGMGLSIVAA--KGAGQDKL---GIYVKSVVKGGAADVDGRLAAGD 1056
K +I V L K N +G+S+ KG + GIYVK+V+ GAA+ DGR+ GD
Sbjct: 1362 KPGDIFEVELAKNDNSLGISVTVLFDKGGVNTSVRHGGIYVKAVIPQGAAESDGRIHKGD 1421
Query: 1057 QLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAK 1091
++L+V+G SL G + ++A E + T VV L + K
Sbjct: 1422 RVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEK 1456
Score = 43.1 bits (100), Expect = 0.002
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 12/107 (11%)
Query: 985 DYESHLLRENTELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGG 1044
D E+HL E+ EL E E++ +K + G L KG ++G YV V++
Sbjct: 1778 DLENHL--EDFEL------EVELLITLIKSEKG-SLGFTVTKG--NQRIGCYVHDVIQDP 1826
Query: 1045 AADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAK 1091
A DGRL GD+L+ V+ + ++ A L+ S V L + +
Sbjct: 1827 AKS-DGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGR 1872
Score = 36.6 bits (83), Expect = 0.21
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 3/78 (3%)
Query: 1013 KKQNGMGLSIVAAKGAGQDKLG---IYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGL 1069
K +G+G S +++ + VK + G A G++ GD +L V+G SL GL
Sbjct: 1511 KNSSGLGFSFSREDNLIPEQINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGL 1570
Query: 1070 SQERAAELMTRTSSVVTL 1087
SQ+ + T+ V L
Sbjct: 1571 SQQEVISALRGTAPEVFL 1588
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,474,551
Number of Sequences: 37866
Number of extensions: 3798248
Number of successful extensions: 53570
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 634
Number of HSP's successfully gapped in prelim test: 1363
Number of HSP's that attempted gapping in prelim test: 22461
Number of HSP's gapped (non-prelim): 16755
length of query: 1651
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1535
effective length of database: 13,855,062
effective search space: 21267520170
effective search space used: 21267520170
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.