Search of human proteins with 90403614

Search of human proteins with 90403614

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|90403614 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform a [Homo sapiens]
         (1093 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|90403614 solute carrier family 4, sodium bicarbonate cotransp...  2221   0.0  
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp...  2088   0.0  
gi|155722998 solute carrier family 4, sodium bicarbonate transpo...  1697   0.0  
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans...  1259   0.0  
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans...  1079   0.0  
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans...  1079   0.0  
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo...  1050   0.0  
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap...   977   0.0  
gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa...   966   0.0  
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans...   808   0.0  
gi|156071474 solute carrier family 4, anion exchanger, member 2 ...   679   0.0  
gi|157671951 solute carrier family 4, anion exchanger, member 3 ...   643   0.0  
gi|157671953 solute carrier family 4, anion exchanger, member 3 ...   643   0.0  
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H...   568   e-161
gi|14042960 solute carrier family 4 member 11 [Homo sapiens]          224   3e-58
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...    35   0.39 
gi|239755074 PREDICTED: hypothetical protein [Homo sapiens]            35   0.51 
gi|239749600 PREDICTED: hypothetical protein XP_002347101 [Homo ...    35   0.51 
gi|239743867 PREDICTED: hypothetical protein XP_002342984 [Homo ...    35   0.51 
gi|27886561 nuclear factor of activated T-cells, cytoplasmic, ca...    34   0.66 
gi|27886559 nuclear factor of activated T-cells, cytoplasmic, ca...    34   0.66 
gi|27886555 nuclear factor of activated T-cells, cytoplasmic, ca...    34   0.66 
gi|4758804 nuclear factor of activated T-cells, cytoplasmic, cal...    34   0.66 
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    34   0.66 
gi|27886563 nuclear factor of activated T-cells, cytoplasmic, ca...    34   0.66 
gi|4504487 histidine rich calcium binding protein precursor [Hom...    33   1.1  
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]     33   1.1  
gi|4557719 DNA ligase I [Homo sapiens]                                 33   1.5  
gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]                      33   1.9  
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    32   4.3  

>gi|90403614 solute carrier family 4, sodium bicarbonate
            cotransporter, member 8 isoform a [Homo sapiens]
          Length = 1093

 Score = 2221 bits (5754), Expect = 0.0
 Identities = 1093/1093 (100%), Positives = 1093/1093 (100%)

Query: 1    MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQS 60
            MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQS
Sbjct: 1    MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQS 60

Query: 61   HRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTEL 120
            HRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTEL
Sbjct: 61   HRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTEL 120

Query: 121  DEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLL 180
            DEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLL
Sbjct: 121  DEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLL 180

Query: 181  DMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAE 240
            DMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAE
Sbjct: 181  DMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAE 240

Query: 241  VGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEA 300
            VGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEA
Sbjct: 241  VGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEA 300

Query: 301  SNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSM 360
            SNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSM
Sbjct: 301  SNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSM 360

Query: 361  ATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK 420
            ATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK
Sbjct: 361  ATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK 420

Query: 421  MPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLA 480
            MPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLA
Sbjct: 421  MPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLA 480

Query: 481  SFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGP 540
            SFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGP
Sbjct: 481  SFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGP 540

Query: 541  VLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASL 600
            VLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASL
Sbjct: 541  VLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASL 600

Query: 601  ICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTA 660
            ICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTA
Sbjct: 601  ICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTA 660

Query: 661  EVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRY 720
            EVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRY
Sbjct: 661  EVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRY 720

Query: 721  FPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPW 780
            FPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPW
Sbjct: 721  FPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPW 780

Query: 781  WTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGL 840
            WTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGL
Sbjct: 781  WTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGL 840

Query: 841  PWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILK 900
            PWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILK
Sbjct: 841  PWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILK 900

Query: 901  FIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQL 960
            FIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQL
Sbjct: 901  FIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQL 960

Query: 961  TCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK 1020
            TCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK
Sbjct: 961  TCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK 1020

Query: 1021 KKAKEEEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALS 1080
            KKAKEEEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALS
Sbjct: 1021 KKAKEEEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALS 1080

Query: 1081 MNSGNAKEKSLFN 1093
            MNSGNAKEKSLFN
Sbjct: 1081 MNSGNAKEKSLFN 1093


>gi|90568034 solute carrier family 4, sodium bicarbonate
            cotransporter, member 8 isoform b [Homo sapiens]
          Length = 1044

 Score = 2088 bits (5411), Expect = 0.0
 Identities = 1027/1027 (100%), Positives = 1027/1027 (100%)

Query: 1    MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQS 60
            MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQS
Sbjct: 1    MPAAGSNEPDGVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQS 60

Query: 61   HRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTEL 120
            HRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTEL
Sbjct: 61   HRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTEL 120

Query: 121  DEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLL 180
            DEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLL
Sbjct: 121  DEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLL 180

Query: 181  DMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAE 240
            DMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAE
Sbjct: 181  DMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAE 240

Query: 241  VGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEA 300
            VGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEA
Sbjct: 241  VGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEA 300

Query: 301  SNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSM 360
            SNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSM
Sbjct: 301  SNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSM 360

Query: 361  ATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK 420
            ATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK
Sbjct: 361  ATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK 420

Query: 421  MPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLA 480
            MPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLA
Sbjct: 421  MPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLA 480

Query: 481  SFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGP 540
            SFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGP
Sbjct: 481  SFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGP 540

Query: 541  VLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASL 600
            VLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASL
Sbjct: 541  VLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASL 600

Query: 601  ICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTA 660
            ICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTA
Sbjct: 601  ICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTA 660

Query: 661  EVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRY 720
            EVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRY
Sbjct: 661  EVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRY 720

Query: 721  FPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPW 780
            FPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPW
Sbjct: 721  FPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPW 780

Query: 781  WTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGL 840
            WTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGL
Sbjct: 781  WTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGL 840

Query: 841  PWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILK 900
            PWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILK
Sbjct: 841  PWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILK 900

Query: 901  FIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQL 960
            FIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQL
Sbjct: 901  FIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQL 960

Query: 961  TCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK 1020
            TCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK
Sbjct: 961  TCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAK 1020

Query: 1021 KKAKEEE 1027
            KKAKEEE
Sbjct: 1021 KKAKEEE 1027


>gi|155722998 solute carrier family 4, sodium bicarbonate
            transporter-like, member 10 [Homo sapiens]
          Length = 1088

 Score = 1697 bits (4395), Expect = 0.0
 Identities = 835/1076 (77%), Positives = 944/1076 (87%), Gaps = 18/1076 (1%)

Query: 17   RPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRG 75
            R DEEAVVD+GGT +IL  H+EKE+LEGHRTL++GV +PLG R+SHR HR  G KHR+R 
Sbjct: 17   RNDEEAVVDRGGTRSILKTHFEKEDLEGHRTLFIGVHVPLGGRKSHRRHRHRGHKHRKRD 76

Query: 76   RGKGASQGEEGLEALAHDTPSQRVQFILGTEED-EEHVPHELFTELDEICMKEGEDAEWK 134
            R + +   E+G E+ + DTPSQRVQFILGTE+D EEH+PH+LFTELDEIC +EGEDAEW+
Sbjct: 77   RERDSGL-EDGRESPSFDTPSQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWR 135

Query: 135  ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLI 194
            ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSC++NGTVLLDMHAN++EEI+D++
Sbjct: 136  ETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMV 195

Query: 195  LDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKH 254
            LDQQ  S  LN+ +R +V EAL+K+HHHQN+KK  N IPIVRSFA++GKKQS+P+ MDK+
Sbjct: 196  LDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKN 255

Query: 255  -GQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDR 313
             GQ VSPQS P   +E KN V+ E+S VD SKVDLHFMKKIP GAEASN+LVGE++ LDR
Sbjct: 256  AGQVVSPQSAPAC-VENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLDR 314

Query: 314  PIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVA 373
             +VAFVRLSPAVLL GL EVPIPTRFLFILLGP+GKGQQYHEIGRS+AT+MTDE+FHDVA
Sbjct: 315  TVVAFVRLSPAVLLQGLAEVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVA 374

Query: 374  YKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIE 433
            YKAK+R+DL++GIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRK+P VPNG   H E
Sbjct: 375  YKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGE 434

Query: 434  QEPHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPV 493
             EPHGGHSGPELQRTGR+FGGL+LDIKRKAP++WSD+RDA SLQCLASFLFLYCACMSPV
Sbjct: 435  AEPHGGHSGPELQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPV 494

Query: 494  ITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCK 553
            ITFGGLLGEATEGRISAIESLFGASMTGIAYSLF GQ LTILGSTGPVLVFEKILFKFCK
Sbjct: 495  ITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCK 554

Query: 554  DYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKL 613
            +Y LSYLSLRA IGLWTA LCI+LVATDASSLVCYITRFTEEAFASLICIIFIYEA+EKL
Sbjct: 555  EYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKL 614

Query: 614  IHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQ 673
              L+E YPI+MH+ L+ L+ Y C C  P NP+N TL+ W++ NI  +++ W NLTVSEC+
Sbjct: 615  FELSEAYPINMHNDLELLTQYSCNCVEPHNPSNGTLKEWRESNISASDIIWENLTVSECK 674

Query: 674  EMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFA 733
             +HGE++G ACGH  PY PDVLFWS ILFF+T  LS+TLK FKTSRYFPT+VRS+VSDFA
Sbjct: 675  SLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDFA 734

Query: 734  VFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLC 793
            VFLTI  MV+ID+ IG+PSPKLQVPSVFKPTRDDRGW + P+GPNPWWTVIAAIIPALLC
Sbjct: 735  VFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALLC 794

Query: 794  TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITH 853
            TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVA+MLGVCSIMGLPWFVAATVLSITH
Sbjct: 795  TILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSITH 854

Query: 854  VNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLY 913
            VNSLKLESECSAPGEQPKFLGIREQRVTGLMIF+LMG SVFMT+ILKFIPMPVLYGVFLY
Sbjct: 855  VNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLY 914

Query: 914  MGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASP 973
            MG SSL+GIQFFDR+KLF MPAKHQPDFIYLRHVPLRKVHLFT+IQ++CL LLW+IK S 
Sbjct: 915  MGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVSR 974

Query: 974  AAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEEAEKML 1033
            AAIVFPMMVLALVFVRK+MDL F+KRELSWLDDLMPESKKKKL+DA+K  +EE+    M 
Sbjct: 975  AAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEK--EEEQSMLAME 1032

Query: 1034 EIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDEMPKTTVWKALSMNSGNAKEK 1089
            + G  + PLE              R DPS INISDEM KT +W+ L + + N+K+K
Sbjct: 1033 DEGTVQLPLEGH-----------YRDDPSVINISDEMSKTALWRNLLITADNSKDK 1077


>gi|134288865 solute carrier family 4, sodium bicarbonate
            cotransporter, member 7 [Homo sapiens]
          Length = 1214

 Score = 1259 bits (3258), Expect = 0.0
 Identities = 634/842 (75%), Positives = 714/842 (84%), Gaps = 16/842 (1%)

Query: 242  GKKQSDPHLMD-KHGQTVSPQSVP-----TTNLEVK---NGVNCEHSPVDLSKVDLHFMK 292
            G++Q +   +D   G   SPQS P     + + E+K   +G + E+S VD SKVD++FM+
Sbjct: 361  GEEQKNEENVDLTPGILASPQSAPGNLDNSKSGEIKGNGSGGSRENSTVDFSKVDMNFMR 420

Query: 293  KIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQ 352
            KIPTGAEASNVLVGEVD L+RPI+AFVRL+PAVLL+GLTEVP+PTRFLF+LLGP GK  Q
Sbjct: 421  KIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQ 480

Query: 353  YHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKN 412
            YHEIGRS+AT+MTDEIFHDVAYKAK+R+DLL+GIDEFLDQVTVLPPGEWDPSIRIEPPK+
Sbjct: 481  YHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKS 540

Query: 413  VPSQEKRKMPGVPNGNVCHIEQEPHGG--HSGPELQRTGRLFGGLVLDIKRKAPWYWSDY 470
            VPSQEKRK+P   NG+   + + P     H+GPELQRTGRLFGGL+LDIKRKAP++ SD+
Sbjct: 541  VPSQEKRKIPVFHNGSTPTLGETPKEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDF 600

Query: 471  RDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQ 530
            +DALSLQCLAS LFLYCACMSPVITFGGLLGEATEGRISAIESLFGAS+TGIAYSLFAGQ
Sbjct: 601  KDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQ 660

Query: 531  ALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYIT 590
             LTILGSTGPVLVFEKIL+KFC+DY LSYLSLR  IGLWT+FLCIVLVATDASSLVCYIT
Sbjct: 661  PLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYIT 720

Query: 591  RFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQ 650
            RFTEEAFA+LICIIFIYEA+EKL  L ETY  +MH+ LD L+ Y C CT P NP+N TL 
Sbjct: 721  RFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSNETLA 780

Query: 651  YWKDHNIVTAEVHWANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSS 710
             WK  NI    + W NLTVSEC+++ G F+GSACGHHGPY PDVLFW  ILFFTTF LSS
Sbjct: 781  QWKKDNITAHNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSS 840

Query: 711  TLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGW 770
             LK FKT RYFPT+VRS +SDFAVFLTI  MV ID+L+GVPSPKL VP  F+PT  +RGW
Sbjct: 841  FLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGW 900

Query: 771  IINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAI 830
            II+P+G NPWWT++ A IPALLCTILIFMDQQITAVIINRKEHKLKKG GYHLDLLMV +
Sbjct: 901  IISPLGDNPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGV 960

Query: 831  MLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMG 890
            MLGVCS+MGLPWFVAATVLSI+HVNSLK+ESECSAPGEQPKFLGIREQRVTGLMIF+LMG
Sbjct: 961  MLGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMG 1020

Query: 891  CSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLR 950
             SVFMT++LKFIPMPVLYGVFLYMGVSSL+GIQ FDR+KLFGMPAKHQPD IYLR+VPL 
Sbjct: 1021 LSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLW 1080

Query: 951  KVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPE 1010
            KVH+FT+IQLTCLVLLWVIK S AA+VFPMMVLALVFVRK+MDLCF+KRELSWLDDLMPE
Sbjct: 1081 KVHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPE 1140

Query: 1011 SKKKKLDDAKKKAKEEEEAEKMLEIGGD--KFPLESRKLLSSPGKNISCRCD-PSEINIS 1067
            SKKKK DD  KK KE+EEAE+ML+   D    P E   LL  P K +    D P  + IS
Sbjct: 1141 SKKKKEDD--KKKKEKEEAERMLQDDDDTVHLPFEGGSLLQIPVKALKYSPDKPVSVKIS 1198

Query: 1068 DE 1069
             E
Sbjct: 1199 FE 1200



 Score =  335 bits (860), Expect = 1e-91
 Identities = 154/243 (63%), Positives = 200/243 (82%), Gaps = 1/243 (0%)

Query: 18  PDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRG 77
           PDEEAVVD G TS+ +N  +EKEELE HR +Y+GV +P  ++S R HR  G KH  R R 
Sbjct: 13  PDEEAVVDLGKTSSTVNTKFEKEELESHRAVYIGVHVPFSKESRRRHRHRGHKHHHRRRK 72

Query: 78  KGASQGEEGLEALAHDTPSQRVQFILGTEED-EEHVPHELFTELDEICMKEGEDAEWKET 136
              S  E+G E+ ++DTPSQRVQFILGTE+D EEH+PH+LFTE+DE+C ++GE+ EWKET
Sbjct: 73  DKESDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKET 132

Query: 137 ARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILD 196
           ARWLKFEEDVEDGG+RWSKPYVATLSLHSLFELRSC++NGTV+LDM A++++EI+D++LD
Sbjct: 133 ARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLD 192

Query: 197 QQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQ 256
               S  L++S+R  VREALLK+HHHQNEK+  + IP+VRSFA++GKK SDPHL++++G+
Sbjct: 193 NMIASGQLDESIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGE 252

Query: 257 TVS 259
            +S
Sbjct: 253 GLS 255


>gi|197927160 solute carrier family 4, sodium bicarbonate
            cotransporter, member 4 isoform 3 [Homo sapiens]
          Length = 1094

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 559/1038 (53%), Positives = 730/1038 (70%), Gaps = 45/1038 (4%)

Query: 19   DEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRGRG 77
            ++EAV+D+G  ++ L    ++EE+EGH T+Y+GV +P   R+  RH R  G K ++    
Sbjct: 2    EDEAVLDRG--ASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKER 59

Query: 78   KGASQGEEGLEALAHDTPS-----------QRVQFILGTEEDEEHVPHELFTELDEICMK 126
               +  ++     A ++ S           +R++FILG EED+   P +LFTELDE+   
Sbjct: 60   ISENYSDKSDIENADESSSSILKPLISPAAERIRFILG-EEDDSPAPPQLFTELDELLAV 118

Query: 127  EGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANS 186
            +G++ EWKETARW+KFEE VE GGERWSKP+VATLSLHSLFELR+C+  G+++LD  A+S
Sbjct: 119  DGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASS 178

Query: 187  IEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQS 246
            + ++ ++I+D Q  +  L   ++ KV   LL+KH HQ +K        +RS A++GK  S
Sbjct: 179  LPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSN------LRSLADIGKTVS 232

Query: 247  DPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVG 306
                M  +    SP ++   NL   + +N      +  ++   FMKK+P  AEASNVLVG
Sbjct: 233  SASRMFTNPDNGSP-AMTHRNL-TSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVG 290

Query: 307  EVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTD 366
            EVD LD P +AFVRL  AV+L  LTEVP+PTRFLFILLGP GK + YHEIGR++AT+M+D
Sbjct: 291  EVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSD 350

Query: 367  EIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPN 426
            E+FHD+AYKAK+R DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK++PS +KRK      
Sbjct: 351  EVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGG 410

Query: 427  GNVCHIEQEPH-GGHSG------PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCL 479
             NV      PH GGH G       ELQRTGR  GGL+ DIKRKAP++ SD+ DAL++Q L
Sbjct: 411  ENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQAL 470

Query: 480  ASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTG 539
            ++ LF+Y A ++  ITFGGLLG+AT+     +ES  G +++G  + LFAGQ LTIL STG
Sbjct: 471  SAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTG 530

Query: 540  PVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFAS 599
            PVLVFE++LF F KD    YL  R  IGLW+AFLC++LVATDAS LV Y TRFTEE F+S
Sbjct: 531  PVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSS 590

Query: 600  LICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPN-----NHTLQYWKD 654
            LI  IFIY+A +K+I LA+ YPI+ + ++ + +L+ C C  P+  N     + TL     
Sbjct: 591  LISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYL 650

Query: 655  HNIVTAEVH------WANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFIL 708
              + + +++      WA L+  EC +  G  +G+ C     + PD+   S ILF  T+  
Sbjct: 651  PTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILFLGTYTS 706

Query: 709  SSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDR 768
            S  LK FKTS YFPT  R ++SDFA+ L+I    +ID L+GV +PKL VPS FKPT  +R
Sbjct: 707  SMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNR 766

Query: 769  GWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMV 828
            GW + P G NPWW  +AA IPALL TILIFMDQQITAVI+NRKEHKLKKG GYHLDL  V
Sbjct: 767  GWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWV 826

Query: 829  AIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVL 888
            AI++ +CS+M LPW+VAATV+SI H++SLK+E+E SAPGEQPKFLG+REQRVTG ++F+L
Sbjct: 827  AILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFIL 886

Query: 889  MGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVP 948
             G SVFM  ILKFIPMPVLYGVFLYMGV+SL G+QF DRLKL  MP KHQPDFIYLRHVP
Sbjct: 887  TGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVP 946

Query: 949  LRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLM 1008
            LR+VHLFT +Q+ CL LLW++K++ AAI+FP+M+LALV VRK MD  FS+ +LS+LDD++
Sbjct: 947  LRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVI 1006

Query: 1009 PESKKKKLDDAKKKAKEE 1026
            PE  KKK +D KKK K++
Sbjct: 1007 PEKDKKKKEDEKKKKKKK 1024


>gi|148596928 solute carrier family 4, sodium bicarbonate
            cotransporter, member 4 isoform 1 [Homo sapiens]
          Length = 1079

 Score = 1079 bits (2790), Expect = 0.0
 Identities = 559/1038 (53%), Positives = 730/1038 (70%), Gaps = 45/1038 (4%)

Query: 19   DEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLG-RQSHRHHRTHGQKHRRRGRG 77
            ++EAV+D+G  ++ L    ++EE+EGH T+Y+GV +P   R+  RH R  G K ++    
Sbjct: 2    EDEAVLDRG--ASFLKHVCDEEEVEGHHTIYIGVHVPKSYRRRRRHKRKTGHKEKKEKER 59

Query: 78   KGASQGEEGLEALAHDTPS-----------QRVQFILGTEEDEEHVPHELFTELDEICMK 126
               +  ++     A ++ S           +R++FILG EED+   P +LFTELDE+   
Sbjct: 60   ISENYSDKSDIENADESSSSILKPLISPAAERIRFILG-EEDDSPAPPQLFTELDELLAV 118

Query: 127  EGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANS 186
            +G++ EWKETARW+KFEE VE GGERWSKP+VATLSLHSLFELR+C+  G+++LD  A+S
Sbjct: 119  DGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASS 178

Query: 187  IEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQS 246
            + ++ ++I+D Q  +  L   ++ KV   LL+KH HQ +K        +RS A++GK  S
Sbjct: 179  LPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSN------LRSLADIGKTVS 232

Query: 247  DPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVG 306
                M  +    SP ++   NL   + +N      +  ++   FMKK+P  AEASNVLVG
Sbjct: 233  SASRMFTNPDNGSP-AMTHRNL-TSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVG 290

Query: 307  EVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTD 366
            EVD LD P +AFVRL  AV+L  LTEVP+PTRFLFILLGP GK + YHEIGR++AT+M+D
Sbjct: 291  EVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSD 350

Query: 367  EIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKMPGVPN 426
            E+FHD+AYKAK+R DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK++PS +KRK      
Sbjct: 351  EVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGG 410

Query: 427  GNVCHIEQEPH-GGHSG------PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCL 479
             NV      PH GGH G       ELQRTGR  GGL+ DIKRKAP++ SD+ DAL++Q L
Sbjct: 411  ENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQAL 470

Query: 480  ASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTG 539
            ++ LF+Y A ++  ITFGGLLG+AT+     +ES  G +++G  + LFAGQ LTIL STG
Sbjct: 471  SAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTG 530

Query: 540  PVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFAS 599
            PVLVFE++LF F KD    YL  R  IGLW+AFLC++LVATDAS LV Y TRFTEE F+S
Sbjct: 531  PVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSS 590

Query: 600  LICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCTLPENPN-----NHTLQYWKD 654
            LI  IFIY+A +K+I LA+ YPI+ + ++ + +L+ C C  P+  N     + TL     
Sbjct: 591  LISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTTLAPEYL 650

Query: 655  HNIVTAEVH------WANLTVSECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFIL 708
              + + +++      WA L+  EC +  G  +G+ C     + PD+   S ILF  T+  
Sbjct: 651  PTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILFLGTYTS 706

Query: 709  SSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDR 768
            S  LK FKTS YFPT  R ++SDFA+ L+I    +ID L+GV +PKL VPS FKPT  +R
Sbjct: 707  SMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNR 766

Query: 769  GWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMV 828
            GW + P G NPWW  +AA IPALL TILIFMDQQITAVI+NRKEHKLKKG GYHLDL  V
Sbjct: 767  GWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWV 826

Query: 829  AIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVL 888
            AI++ +CS+M LPW+VAATV+SI H++SLK+E+E SAPGEQPKFLG+REQRVTG ++F+L
Sbjct: 827  AILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFIL 886

Query: 889  MGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVP 948
             G SVFM  ILKFIPMPVLYGVFLYMGV+SL G+QF DRLKL  MP KHQPDFIYLRHVP
Sbjct: 887  TGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVP 946

Query: 949  LRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLM 1008
            LR+VHLFT +Q+ CL LLW++K++ AAI+FP+M+LALV VRK MD  FS+ +LS+LDD++
Sbjct: 947  LRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVI 1006

Query: 1009 PESKKKKLDDAKKKAKEE 1026
            PE  KKK +D KKK K++
Sbjct: 1007 PEKDKKKKEDEKKKKKKK 1024


>gi|4507025 solute carrier family 4, sodium bicarbonate cotransporter,
            member 4 isoform 2 [Homo sapiens]
          Length = 1035

 Score = 1050 bits (2716), Expect = 0.0
 Identities = 535/949 (56%), Positives = 687/949 (72%), Gaps = 31/949 (3%)

Query: 96   SQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSK 155
            ++R++FILG EED+   P +LFTELDE+   +G++ EWKETARW+KFEE VE GGERWSK
Sbjct: 45   AERIRFILG-EEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSK 103

Query: 156  PYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREA 215
            P+VATLSLHSLFELR+C+  G+++LD  A+S+ ++ ++I+D Q  +  L   ++ KV   
Sbjct: 104  PHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYT 163

Query: 216  LLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVN 275
            LL+KH HQ +K        +RS A++GK  S    M  +    SP ++   NL   + +N
Sbjct: 164  LLRKHRHQTKKSN------LRSLADIGKTVSSASRMFTNPDNGSP-AMTHRNL-TSSSLN 215

Query: 276  CEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPI 335
                  +  ++   FMKK+P  AEASNVLVGEVD LD P +AFVRL  AV+L  LTEVP+
Sbjct: 216  DISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPV 275

Query: 336  PTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTV 395
            PTRFLFILLGP GK + YHEIGR++AT+M+DE+FHD+AYKAK+R DL+AGIDEFLD+V V
Sbjct: 276  PTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIV 335

Query: 396  LPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPH-GGHSG------PELQRT 448
            LPPGEWDP+IRIEPPK++PS +KRK       NV      PH GGH G       ELQRT
Sbjct: 336  LPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRT 395

Query: 449  GRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRI 508
            GR  GGL+ DIKRKAP++ SD+ DAL++Q L++ LF+Y A ++  ITFGGLLG+AT+   
Sbjct: 396  GRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQ 455

Query: 509  SAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGL 568
              +ES  G +++G  + LFAGQ LTIL STGPVLVFE++LF F KD    YL  R  IGL
Sbjct: 456  GVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGL 515

Query: 569  WTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQL 628
            W+AFLC++LVATDAS LV Y TRFTEE F+SLI  IFIY+A +K+I LA+ YPI+ + ++
Sbjct: 516  WSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKV 575

Query: 629  DHLSLYYCRCTLPENPN-----NHTLQYWKDHNIVTAEVH------WANLTVSECQEMHG 677
             + +L+ C C  P+  N     + TL       + + +++      WA L+  EC +  G
Sbjct: 576  GYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGG 635

Query: 678  EFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLT 737
              +G+ C     + PD+   S ILF  T+  S  LK FKTS YFPT  R ++SDFA+ L+
Sbjct: 636  NLVGNNCN----FVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILS 691

Query: 738  IFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILI 797
            I    +ID L+GV +PKL VPS FKPT  +RGW + P G NPWW  +AA IPALL TILI
Sbjct: 692  ILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILI 751

Query: 798  FMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSL 857
            FMDQQITAVI+NRKEHKLKKG GYHLDL  VAI++ +CS+M LPW+VAATV+SI H++SL
Sbjct: 752  FMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSL 811

Query: 858  KLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVS 917
            K+E+E SAPGEQPKFLG+REQRVTG ++F+L G SVFM  ILKFIPMPVLYGVFLYMGV+
Sbjct: 812  KMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVA 871

Query: 918  SLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIV 977
            SL G+QF DRLKL  MP KHQPDFIYLRHVPLR+VHLFT +Q+ CL LLW++K++ AAI+
Sbjct: 872  SLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAII 931

Query: 978  FPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEE 1026
            FP+M+LALV VRK MD  FS+ +LS+LDD++PE  KKK +D KKK K++
Sbjct: 932  FPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKK 980


>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
          Length = 1121

 Score =  977 bits (2525), Expect = 0.0
 Identities = 514/1052 (48%), Positives = 695/1052 (66%), Gaps = 84/1052 (7%)

Query: 75   GRGKGASQGEEGLEALAH--DTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAE 132
            G G GAS  +  ++ ++      ++++Q ILG EEDE   P  LFTE+D +   +G+  E
Sbjct: 72   GPGSGASSQDSSMDLISRTRSPAAEQLQDILG-EEDEAPNP-TLFTEMDTL-QHDGDQME 128

Query: 133  WKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISD 192
            WKE+ARW+KFEE VE+GGERWSKP+V+TLSLHSLFELR+CL  GTVLLD+ + S+ +I D
Sbjct: 129  WKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIID 188

Query: 193  LILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMD 252
             ++++Q     L   +R +V   LL++H HQ +K      PI RS A++GK  S  +   
Sbjct: 189  DVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIHRSLADIGKSVSTTNRSP 242

Query: 253  KHGQTVSPQSVPTT-NLEVKNGVN----CEHSPVDLSKVDL---------HFMKKIPTGA 298
                   P    +T +L ++   N    C      ++ + L          FMKKIP  +
Sbjct: 243  ARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDS 302

Query: 299  EASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGR 358
            EASNVLVGEVD LD+P +AFVRL  + +L G+TEVP+PTRFLFILLGP G+ + Y+EIGR
Sbjct: 303  EASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGR 362

Query: 359  SMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEK 418
            ++AT+M D++F DVAYKA+ R+DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK VPS +K
Sbjct: 363  AIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADK 422

Query: 419  RKMP------GVPNGNVCHIEQEPHGGHSG------------------------------ 442
            RK        G  NG+V      P GG+ G                              
Sbjct: 423  RKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMH 482

Query: 443  ---PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGL 499
                EL  TGR FGGL LDIKRK PW+ SD+ D   +Q +++ LF+Y  C++  ITFGGL
Sbjct: 483  EIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGL 542

Query: 500  LGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSY 559
            LG+AT+     +ES  G +M G  + LF+GQ L IL STGP+L+FEK+LF F K   L Y
Sbjct: 543  LGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDY 602

Query: 560  LSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAET 619
            +  R  IGL +A  C++LVATDAS ++ YITRFTEE F++LI  IFIY+AI+K+I   + 
Sbjct: 603  MEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKY 662

Query: 620  YPIHMHSQLDHLSLYYCRCTLPENPN----NHTLQYWKDHN------IVTAEVHWANLTV 669
            YPI+M  + + ++ Y C C  P+  N    N +     D N      +    + W+ L+ 
Sbjct: 663  YPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSK 722

Query: 670  SECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMV 729
             EC    G  +G++C     + PD+   S ILFF T+ ++ TLK FK SRYFPT+VR++V
Sbjct: 723  KECLSYGGRLLGNSC----KFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALV 778

Query: 730  SDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIP 789
            +DF++  +I     ID   G+ +PKL VPSV KPTR DRGW + P G NPWW   A+I+P
Sbjct: 779  ADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILP 838

Query: 790  ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 849
            ALL TILIFMDQQITAVI+NRKE+KLKK  GYHLDL  V I++ +CS MGLPW+VAATV+
Sbjct: 839  ALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVI 898

Query: 850  SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 909
            SI H++SLK+E+E SAPGEQP+FLG+REQRVTG+++F+L G SVF+  ILK IP+PVLYG
Sbjct: 899  SIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYG 958

Query: 910  VFLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVI 969
            VFLYMGV+SL GIQF++R KLF MPAKHQPD  +LRHVPLR++HLFTL+Q+ CL +LW++
Sbjct: 959  VFLYMGVASLNGIQFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWIL 1018

Query: 970  KASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAK----E 1025
            K++ AAI+FP+M+L L+ VR+++D  FS+ +L+W+D+++PE +KK+ D  +K+ K    +
Sbjct: 1019 KSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEKKETDKKRKRKKGAHED 1078

Query: 1026 EEEAEKMLEIGGDKFPLESRKLLSSPGKNISC 1057
             +E  +       K P+ES  + S P   I C
Sbjct: 1079 CDEEPQFPPPSVIKIPMES--VQSDPQNGIHC 1108


>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
            sapiens]
          Length = 1137

 Score =  966 bits (2498), Expect = 0.0
 Identities = 514/1068 (48%), Positives = 695/1068 (65%), Gaps = 100/1068 (9%)

Query: 75   GRGKGASQGEEGLEALAH--DTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAE 132
            G G GAS  +  ++ ++      ++++Q ILG EEDE   P  LFTE+D +   +G+  E
Sbjct: 72   GPGSGASSQDSSMDLISRTRSPAAEQLQDILG-EEDEAPNP-TLFTEMDTL-QHDGDQME 128

Query: 133  WKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISD 192
            WKE+ARW+KFEE VE+GGERWSKP+V+TLSLHSLFELR+CL  GTVLLD+ + S+ +I D
Sbjct: 129  WKESARWIKFEEKVEEGGERWSKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIID 188

Query: 193  LILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMD 252
             ++++Q     L   +R +V   LL++H HQ +K      PI RS A++GK  S  +   
Sbjct: 189  DVIEKQIEDGLLRPELRERVSYVLLRRHRHQTKK------PIHRSLADIGKSVSTTNRSP 242

Query: 253  KHGQTVSPQSVPTT-NLEVKNGVN----CEHSPVDLSKVDL---------HFMKKIPTGA 298
                   P    +T +L ++   N    C      ++ + L          FMKKIP  +
Sbjct: 243  ARSPGAGPSLHHSTEDLRMRQSANYGRLCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDS 302

Query: 299  EASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGR 358
            EASNVLVGEVD LD+P +AFVRL  + +L G+TEVP+PTRFLFILLGP G+ + Y+EIGR
Sbjct: 303  EASNVLVGEVDFLDQPFIAFVRLIQSAMLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGR 362

Query: 359  SMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEK 418
            ++AT+M D++F DVAYKA+ R+DL+AGIDEFLD+V VLPPGEWDP+IRIEPPK VPS +K
Sbjct: 363  AIATLMVDDLFSDVAYKARNREDLIAGIDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADK 422

Query: 419  RKMP------GVPNGNVCHIEQEPHGGHSG------------------------------ 442
            RK        G  NG+V      P GG+ G                              
Sbjct: 423  RKSVFSLAELGQMNGSVGGGGGAPGGGNGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMH 482

Query: 443  ---PELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGL 499
                EL  TGR FGGL LDIKRK PW+ SD+ D   +Q +++ LF+Y  C++  ITFGGL
Sbjct: 483  EIGEELIWTGRFFGGLCLDIKRKLPWFPSDFYDGFHIQSISAILFIYLGCITNAITFGGL 542

Query: 500  LGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSY 559
            LG+AT+     +ES  G +M G  + LF+GQ L IL STGP+L+FEK+LF F K   L Y
Sbjct: 543  LGDATDNYQGVMESFLGTAMAGSLFCLFSGQPLIILSSTGPILIFEKLLFDFSKGNGLDY 602

Query: 560  LSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAET 619
            +  R  IGL +A  C++LVATDAS ++ YITRFTEE F++LI  IFIY+AI+K+I   + 
Sbjct: 603  MEFRLWIGLHSAVQCLILVATDASFIIKYITRFTEEGFSTLISFIFIYDAIKKMIGAFKY 662

Query: 620  YPIHMHSQLDHLSLYYCRCTLPENPN----NHTLQYWKDHN------IVTAEVHWANLTV 669
            YPI+M  + + ++ Y C C  P+  N    N +     D N      +    + W+ L+ 
Sbjct: 663  YPINMDFKPNFITTYKCECVAPDTVNTTVFNASAPLAPDTNASLYNLLNLTALDWSLLSK 722

Query: 670  SECQEMHGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMV 729
             EC    G  +G++C     + PD+   S ILFF T+ ++ TLK FK SRYFPT+VR++V
Sbjct: 723  KECLSYGGRLLGNSC----KFIPDLALMSFILFFGTYSMTLTLKKFKFSRYFPTKVRALV 778

Query: 730  SDFAVFLTIFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIP 789
            +DF++  +I     ID   G+ +PKL VPSV KPTR DRGW + P G NPWW   A+I+P
Sbjct: 779  ADFSIVFSILMFCGIDACFGLETPKLHVPSVIKPTRPDRGWFVAPFGKNPWWVYPASILP 838

Query: 790  ALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVL 849
            ALL TILIFMDQQITAVI+NRKE+KLKK  GYHLDL  V I++ +CS MGLPW+VAATV+
Sbjct: 839  ALLVTILIFMDQQITAVIVNRKENKLKKAAGYHLDLFWVGILMALCSFMGLPWYVAATVI 898

Query: 850  SITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYG 909
            SI H++SLK+E+E SAPGEQP+FLG+REQRVTG+++F+L G SVF+  ILK IP+PVLYG
Sbjct: 899  SIAHIDSLKMETETSAPGEQPQFLGVREQRVTGIIVFILTGISVFLAPILKCIPLPVLYG 958

Query: 910  VFLYMGVSSLQGIQ----------------FFDRLKLFGMPAKHQPDFIYLRHVPLRKVH 953
            VFLYMGV+SL GIQ                F++R KLF MPAKHQPD  +LRHVPLR++H
Sbjct: 959  VFLYMGVASLNGIQMGTGGSEFKIQKKLTPFWERCKLFLMPAKHQPDHAFLRHVPLRRIH 1018

Query: 954  LFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKK 1013
            LFTL+Q+ CL +LW++K++ AAI+FP+M+L L+ VR+++D  FS+ +L+W+D+++PE +K
Sbjct: 1019 LFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQHDLAWIDNILPEKEK 1078

Query: 1014 KKLDDAKKKAK----EEEEAEKMLEIGGDKFPLESRKLLSSPGKNISC 1057
            K+ D  +K+ K    + +E  +       K P+ES  + S P   I C
Sbjct: 1079 KETDKKRKRKKGAHEDCDEEPQFPPPSVIKIPMES--VQSDPQNGIHC 1124


>gi|151101449 solute carrier family 4, sodium bicarbonate
            cotransporter, member 9 [Homo sapiens]
          Length = 959

 Score =  808 bits (2087), Expect = 0.0
 Identities = 436/928 (46%), Positives = 592/928 (63%), Gaps = 67/928 (7%)

Query: 105  TEEDEEHVPHE--LFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLS 162
            TE  E  VP +  LF +L+E+ +   +  EW+ET RW+ FEE +E    RWS P+V TL+
Sbjct: 43   TESKELGVPKDPLLFIQLNEL-LGWPQALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLA 101

Query: 163  LHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHH 222
            L SL +LRS L  G VLLD  A S+ E+ + +   + LS +L    R +++  LL++  H
Sbjct: 102  LPSLQKLRSLLAEGLVLLDCPAQSLLELVEQVTRVESLSPEL----RGQLQALLLQRPQH 157

Query: 223  QNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHSPVD 282
             N+                      P     H +  S         + +N +        
Sbjct: 158  YNQTTGTR-----------------PCWGSTHPRKASDNEEAPLREQCQNPLR------- 193

Query: 283  LSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFI 342
                     +K+P GAEA  VL GE+  L +P+ AFVRL   V+L  LTEV +P+RF  +
Sbjct: 194  ---------QKLPPGAEAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCL 244

Query: 343  LLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWD 402
            LLGP   G+ YHE+GR+ A +++D  F     +A    DLLA +D FL++VTVLPPG WD
Sbjct: 245  LLGPCMLGKGYHEMGRAAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWD 304

Query: 403  PSIRIEPPKNVPSQEKR--------KMPGVPNGNVCHIEQEPHGGHS-GPELQRTGRLFG 453
            P+ RI PPK +PSQ KR        + P VP       ++  HG H+  PELQRTGRLFG
Sbjct: 305  PTARIPPPKCLPSQHKRLPSQQREIRGPAVPRLTSAE-DRHRHGPHAHSPELQRTGRLFG 363

Query: 454  GLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIES 513
            GL+ D++RK PWY SD+ DAL LQC ++ L++Y A ++  ITFGGLLG+AT+G    +ES
Sbjct: 364  GLIQDVRRKVPWYPSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLES 423

Query: 514  LFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFL 573
              G ++ G A+ L AGQ LTIL STGPVLVFE++LF F +DY+L YL  R  +G+W A  
Sbjct: 424  FLGTAVAGAAFCLMAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATF 483

Query: 574  CIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSL 633
            C+VLVAT+AS LV Y TRFTEE F +LI +IFIY+A+ K+++L  TYPI    Q    S 
Sbjct: 484  CLVLVATEASVLVRYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPI----QKPGSSA 539

Query: 634  YYCRCTLPENPNNHTLQYWKDH-----NIVTAEVHWANLTV---SECQEMHGEFMGSACG 685
            Y C C  P  P  +  Q+ +       +IV+ ++   N ++    EC    G   G  C 
Sbjct: 540  YGCLCQYP-GPGGNESQWIRTRPKDRDDIVSMDLGLINASLLPPPECTRQGGHPRGPGCH 598

Query: 686  HHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIID 745
                  PD+ F+S +LF T+F  +  LK  KTSR+FP+ VR  +SDF+  L I     +D
Sbjct: 599  T----VPDIAFFSLLLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLD 654

Query: 746  FLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQITA 805
              +G+ +PKL VP  FKPT   RGW+++P G NPWW  +AA +PALL +ILIFMDQQITA
Sbjct: 655  AFLGLATPKLMVPREFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITA 714

Query: 806  VIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSA 865
            VI+NR E++L+KG G+HLDL  VA+++ + S +GLPW+V+ATV+S+ H++SL+ ES   A
Sbjct: 715  VILNRMEYRLQKGAGFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACA 774

Query: 866  PGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFF 925
            PGE+P FLGIREQR+TGL++F+L G S+F+  +LKFIPMPVLYG+FLYMGV++L  IQF 
Sbjct: 775  PGERPNFLGIREQRLTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFT 834

Query: 926  DRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLAL 985
            +R+KL  MPAKHQPD + LRHVPL +VHLFT IQL CL LLW+IK++PAAI+FP+M+L L
Sbjct: 835  NRVKLLLMPAKHQPDLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGL 894

Query: 986  VFVRKVMDLCFSKRELSWLDDLMPESKK 1013
            V VRK ++  FS +EL WLD+LMPE ++
Sbjct: 895  VGVRKALERVFSPQELLWLDELMPEEER 922


>gi|156071474 solute carrier family 4, anion exchanger, member 2
            (erythrocyte membrane protein band 3-like 1) [Homo
            sapiens]
          Length = 1241

 Score =  679 bits (1753), Expect = 0.0
 Identities = 404/1037 (38%), Positives = 587/1037 (56%), Gaps = 90/1037 (8%)

Query: 11   GVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRMPLGRQSHRHHRTHG-Q 69
            G  SY   +   +    G    L      +E+E        + +    +SHR     G +
Sbjct: 229  GHRSYNLQERRRIGSMTGAEQALLPRVPTDEIEAQTLATADLDL---MKSHRFEDVPGVR 285

Query: 70   KHRRRGRGKGASQ-GEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKEG 128
            +H  R   KG++Q G EG E     TP  R +          H PHE+F EL+E+ + + 
Sbjct: 286  RHLVRKNAKGSTQSGREGREP--GPTPRARPR--------APHKPHEVFVELNELLLDKN 335

Query: 129  EDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIE 188
            ++ +W+ETARW+KFEEDVE+  ERW KP+VA+LS  SL ELR  L +G VLLD+   ++ 
Sbjct: 336  QEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLP 395

Query: 189  EISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGK----- 243
             ++  +++Q  +S  +    R  V  ALL KH H +++K  +  P   S   +G      
Sbjct: 396  GVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSF-PRNISAGSLGSLLGHH 454

Query: 244  ----KQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVNCEHS--PVDL----SKVDLHFMKK 293
                 +SDPH+ +          VP T LEV+          P  +    SK +L  ++K
Sbjct: 455  HGQGAESDPHVTEP-----LMGGVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEK 509

Query: 294  IPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQY 353
            IP  AEA+ VLVG V+ L RP +AFVRL  AV L  + EVP+P RFLF+LLGP      Y
Sbjct: 510  IPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDY 569

Query: 354  HEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPGEWDPSIRIEPPKNV 413
            HEIGRS++T+M+D+ FH+ AY A ER+DLL  I+ FLD   VLPP E      +    + 
Sbjct: 570  HEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEELLRSVAHF 629

Query: 414  PSQ--EKRKMPG--VPNGNVCHIEQ----------EPHGGHSGPELQRTGRLFGGLVLDI 459
              Q  +KR+  G  +P G     +           E  G      L+RTGR FGGL+ D+
Sbjct: 630  QRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRPFGGLIRDV 689

Query: 460  KRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASM 519
            +R+ P Y SD+RDAL  QCLA+ +F+Y A +SP ITFGGLLGE T+  I   E +   ++
Sbjct: 690  RRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTAL 749

Query: 520  TGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLWTAFLCIVLVA 579
             G+ + L   Q L ++G +GP+LVFE+  F FC    L YL  R  IG W  FL +++VA
Sbjct: 750  QGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVFLALLMVA 809

Query: 580  TDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLDHLSLYYCRCT 639
             + S LV +++RFT+E FA LI +IFIYE   KL+ + + +P+H  S  +          
Sbjct: 810  LEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCSASN---------- 859

Query: 640  LPENPNNHTLQYWKDHNIVTAEVHWA-NLTVSECQEMHGEFMGSACGHHGP----YTPDV 694
                               ++EV    N+T +  +   G    S  G  G       P+ 
Sbjct: 860  -------------------SSEVDGGENMTWAGARPTLGPGNRSLAGQSGQGKPRGQPNT 900

Query: 695  LFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVIIDFLI-GVPSP 753
               S +L   TF ++  L+ FK SR+FP R+R ++ DF V + I  MV++D+ I    + 
Sbjct: 901  ALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIEDTYTQ 960

Query: 754  KLQVPSVFKPTR-DDRGWIINPIG---PNPWWTVIAAIIPALLCTILIFMDQQITAVIIN 809
            KL VPS F  T  + RGW+INP+G   P P W ++A+++PA+L  ILIFM+ QIT +II+
Sbjct: 961  KLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITTLIIS 1020

Query: 810  RKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQ 869
            +KE  L+KG G+HLDLL++  M G+C++ GLPW  AATV S+TH N+L + S+  APG++
Sbjct: 1021 KKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDK 1080

Query: 870  PKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSSLQGIQFFDRLK 929
            PK   ++EQRVTGL++ +L+G S+ +  +L+ IP+ VL+G+FLYMGV+SL GIQF++RL 
Sbjct: 1081 PKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLH 1140

Query: 930  LFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVFPMMVLALVFVR 989
            L  MP KH PD  Y++ V   ++HLFT +QL CL LLW + ++ A++ FP +++  V +R
Sbjct: 1141 LLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLR 1200

Query: 990  K-VMDLCFSKRELSWLD 1005
              V+   F+ RE+  LD
Sbjct: 1201 MVVLTRIFTDREMKCLD 1217


>gi|157671951 solute carrier family 4, anion exchanger, member 3
            isoform 1 [Homo sapiens]
          Length = 1232

 Score =  643 bits (1658), Expect = 0.0
 Identities = 370/928 (39%), Positives = 534/928 (57%), Gaps = 71/928 (7%)

Query: 113  PHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSC 172
            PHE+F EL+E+ +   ++  W+ETARW+KFEEDVE+  ERW KP+VA+LS  SL ELR  
Sbjct: 318  PHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 377

Query: 173  LINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLI 232
            + +G  LLD+   ++  I+ L+++   +S  +    R  V   LL KH H N+ K +   
Sbjct: 378  IAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFF 437

Query: 233  PIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEV-------KNGVNCEHSPVDLSK 285
            P   S + +     + H    HG      +VPT   ++        +  + +  P+ +  
Sbjct: 438  PRNPSSSSMNSVLGNHHPTPSHGPD---GAVPTMADDLGEPAPLWPHDPDAKEKPLHMPG 494

Query: 286  VDLH------FMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRF 339
             D H       ++KIP  AEA+ VLVG V  L++P  AFVRL+ AVLL  + EVP+P RF
Sbjct: 495  GDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRF 554

Query: 340  LFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPG 399
            LF++LGP      YHE+GRS+AT+M+D++FH+ AY+A +R DLL+ I EFLD   V+PP 
Sbjct: 555  LFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPS 614

Query: 400  EWD--------PSIRIEPPKNVPSQEKRKMPGVPNGNVC----HIEQEPHGGHSGPE--- 444
            E +         + + E  +    +E+ K+     G        +  E  G  + PE   
Sbjct: 615  EVEGRDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDP 674

Query: 445  LQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEAT 504
            L RTG +FGGLV D++R+ P Y SD RDAL  QC+A+ LF+Y A +SP ITFGGLLGE T
Sbjct: 675  LLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKT 734

Query: 505  EGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRA 564
            EG +   E +   ++ G+ +SL   Q L ++G +GP+LVFE+  FKFC+   L YL+ R 
Sbjct: 735  EGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRV 794

Query: 565  CIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHM 624
             +GLW     + LVA + S LV YI+ FT+E FA LI +IFIYE   KL  +   +P+  
Sbjct: 795  WVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPL-- 852

Query: 625  HSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSAC 684
                           LP  P    L+   D  +                E +G  +    
Sbjct: 853  ---------------LPFYPPEGALEGSLDAGL----------------EPNGSALPPTE 881

Query: 685  GHHGPYT-PDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVI 743
            G   P   P+    S IL   TF ++  L+ F+ SR+   + R ++ DF + ++I  MV+
Sbjct: 882  GPPSPRNQPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVL 941

Query: 744  IDFLI-GVPSPKLQVPSVFKPTR-DDRGWIINPIG---PNPWWTVIAAIIPALLCTILIF 798
            +D+ I    + KL VP+    T  D R W I P+G   P P W ++AA +PALL  ILIF
Sbjct: 942  VDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIF 1001

Query: 799  MDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLK 858
            M+ QITA+I+++K  +L KG G+HLDLL++  + G+C + GLPW  AATV S+THVN+L 
Sbjct: 1002 METQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALT 1061

Query: 859  LESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSS 918
            +     APG++P+   +REQRVTG++I  L+G S+ M A+L+ IP+ VL+G+FLYMGV+S
Sbjct: 1062 VMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTS 1121

Query: 919  LQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVF 978
            L GIQ   RL L  MPAKH P+  Y+  V   ++HLFT IQL C+ LLWV+K++ A++ F
Sbjct: 1122 LSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAF 1181

Query: 979  PMMVLALVFVRK-VMDLCFSKRELSWLD 1005
            P ++L  V +R  ++   F  REL  LD
Sbjct: 1182 PFLLLLTVPLRHCLLPRLFQDRELQALD 1209


>gi|157671953 solute carrier family 4, anion exchanger, member 3
            isoform 2 [Homo sapiens]
          Length = 1259

 Score =  643 bits (1658), Expect = 0.0
 Identities = 370/928 (39%), Positives = 534/928 (57%), Gaps = 71/928 (7%)

Query: 113  PHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSC 172
            PHE+F EL+E+ +   ++  W+ETARW+KFEEDVE+  ERW KP+VA+LS  SL ELR  
Sbjct: 345  PHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 404

Query: 173  LINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREALLKKHHHQNEKKRNNLI 232
            + +G  LLD+   ++  I+ L+++   +S  +    R  V   LL KH H N+ K +   
Sbjct: 405  IAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKDSGFF 464

Query: 233  PIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEV-------KNGVNCEHSPVDLSK 285
            P   S + +     + H    HG      +VPT   ++        +  + +  P+ +  
Sbjct: 465  PRNPSSSSMNSVLGNHHPTPSHGPD---GAVPTMADDLGEPAPLWPHDPDAKEKPLHMPG 521

Query: 286  VDLH------FMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPIPTRF 339
             D H       ++KIP  AEA+ VLVG V  L++P  AFVRL+ AVLL  + EVP+P RF
Sbjct: 522  GDGHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRF 581

Query: 340  LFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTVLPPG 399
            LF++LGP      YHE+GRS+AT+M+D++FH+ AY+A +R DLL+ I EFLD   V+PP 
Sbjct: 582  LFVMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPS 641

Query: 400  EWD--------PSIRIEPPKNVPSQEKRKMPGVPNGNVC----HIEQEPHGGHSGPE--- 444
            E +         + + E  +    +E+ K+     G        +  E  G  + PE   
Sbjct: 642  EVEGRDLLRSVAAFQRELLRKRREREQTKVEMTTRGGYTAPGKELSLELGGSEATPEDDP 701

Query: 445  LQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEAT 504
            L RTG +FGGLV D++R+ P Y SD RDAL  QC+A+ LF+Y A +SP ITFGGLLGE T
Sbjct: 702  LLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGEKT 761

Query: 505  EGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRA 564
            EG +   E +   ++ G+ +SL   Q L ++G +GP+LVFE+  FKFC+   L YL+ R 
Sbjct: 762  EGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTGRV 821

Query: 565  CIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHM 624
             +GLW     + LVA + S LV YI+ FT+E FA LI +IFIYE   KL  +   +P+  
Sbjct: 822  WVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPL-- 879

Query: 625  HSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGSAC 684
                           LP  P    L+   D  +                E +G  +    
Sbjct: 880  ---------------LPFYPPEGALEGSLDAGL----------------EPNGSALPPTE 908

Query: 685  GHHGPYT-PDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVI 743
            G   P   P+    S IL   TF ++  L+ F+ SR+   + R ++ DF + ++I  MV+
Sbjct: 909  GPPSPRNQPNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFGIPISILVMVL 968

Query: 744  IDFLI-GVPSPKLQVPSVFKPTR-DDRGWIINPIG---PNPWWTVIAAIIPALLCTILIF 798
            +D+ I    + KL VP+    T  D R W I P+G   P P W ++AA +PALL  ILIF
Sbjct: 969  VDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAVPALLVLILIF 1028

Query: 799  MDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLK 858
            M+ QITA+I+++K  +L KG G+HLDLL++  + G+C + GLPW  AATV S+THVN+L 
Sbjct: 1029 METQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATVRSVTHVNALT 1088

Query: 859  LESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVSS 918
            +     APG++P+   +REQRVTG++I  L+G S+ M A+L+ IP+ VL+G+FLYMGV+S
Sbjct: 1089 VMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLFGIFLYMGVTS 1148

Query: 919  LQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIVF 978
            L GIQ   RL L  MPAKH P+  Y+  V   ++HLFT IQL C+ LLWV+K++ A++ F
Sbjct: 1149 LSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWVVKSTAASLAF 1208

Query: 979  PMMVLALVFVRK-VMDLCFSKRELSWLD 1005
            P ++L  V +R  ++   F  REL  LD
Sbjct: 1209 PFLLLLTVPLRHCLLPRLFQDRELQALD 1236


>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
            sapiens]
          Length = 911

 Score =  568 bits (1463), Expect = e-161
 Identities = 350/966 (36%), Positives = 533/966 (55%), Gaps = 109/966 (11%)

Query: 88   EALAHDTPSQRVQFILGTEEDEEHVPHELFTELDEICMKE-GEDAEWKETARWLKFEEDV 146
            E  AHDT +    +   +        H+++ EL E+ M E  ++  W E ARW++ EE++
Sbjct: 33   EPAAHDTEATATDYHTTSHPGT----HKVYVELQELVMDEKNQELRWMEAARWVQLEENL 88

Query: 147  EDGGERWSKPYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLND 206
             + G  W +P+++ L+  SL ELR     GTVLLD+   S+  +++ +LD+      +  
Sbjct: 89   GENGA-WGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRP 147

Query: 207  SMRVKVREALLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTT 266
              R ++  ALL KH H  E +           A  G K   P ++ + G    P     +
Sbjct: 148  QDREELLRALLLKHSHAGELE-----------ALGGVK---PAVLTRSGDPSQPLLPQHS 193

Query: 267  NLEVK------NGVNCEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVR 320
            +LE +      +G    HSP  +       ++KIP  +EA+ VLVG  D L++P++ FVR
Sbjct: 194  SLETQLFCEQGDGGTEGHSPSGI-------LEKIPPDSEATLVLVGRADFLEQPVLGFVR 246

Query: 321  LSPAVLLSGLTEVPIPTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERD 380
            L  A  L  + E+P+P RFLF+LLGP      Y ++GR+ AT+M++ +F   AY A+ R 
Sbjct: 247  LQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRG 305

Query: 381  DLLAGIDEFLDQVTVLPPGEWDPSIR-----IEPPKNVPSQEKRKMPGVPNGNVCHIEQE 435
            +LL  ++ FLD   VLPP +  PS +     +   + +  +  +  P  P+ +  +   +
Sbjct: 306  ELLHSLEGFLDCSLVLPPTD-APSEQALLSLVPVQRELLRRRYQSSPAKPDSSF-YKGLD 363

Query: 436  PHGGHSGPELQRTGRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVIT 495
             +GG   P LQ+TG+LFGGLV DI+R+ P+Y SD  DA S Q LA+ +F+Y A +SP IT
Sbjct: 364  LNGGPDDP-LQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAIT 422

Query: 496  FGGLLGEATEGRISAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDY 555
            FGGLLGE T  ++   E L   ++ GI ++L   Q L ++G +GP+LVFE+  F FC+  
Sbjct: 423  FGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETN 482

Query: 556  ALSYLSLRACIGLWTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIH 615
             L Y+  R  IG W   L +++VA + S LV +I+R+T+E F+ LI +IFIYE   KLI 
Sbjct: 483  GLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIK 542

Query: 616  LAETYPIHMHSQLDHLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEM 675
            + +                           +H LQ   ++N+         L V + Q  
Sbjct: 543  IFQ---------------------------DHPLQKTYNYNV---------LMVPKPQ-- 564

Query: 676  HGEFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVF 735
                        GP  P+    S +L   TF  +  L+ FK S YFP ++R ++ DF V 
Sbjct: 565  ------------GP-LPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVP 611

Query: 736  LTIFTMVIIDFLI-GVPSPKLQVPSVFKPTRDD-RGWIINPIGPN---PWWTVIAAIIPA 790
            ++I  MV++DF I    + KL VP  FK +    RGW+I+P+G     P W + A+ +PA
Sbjct: 612  ISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPA 671

Query: 791  LLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLS 850
            LL  ILIF++ QIT +I+++ E K+ KG G+HLDLL+V  M GV ++ G+PW  A TV S
Sbjct: 672  LLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRS 731

Query: 851  ITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGV 910
            +TH N+L +  + S PG   +   ++EQR++GL++ VL+G S+ M  IL  IP+ VL+G+
Sbjct: 732  VTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGI 791

Query: 911  FLYMGVSSLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIK 970
            FLYMGV+SL GIQ FDR+ L   P K+ PD  Y++ V   ++HLFT IQ+ CL +LWV+K
Sbjct: 792  FLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVK 851

Query: 971  ASPAAIVFPMMVLALVFVRKV-MDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEEEEA 1029
            ++PA++  P +++  V +R+V + L F   EL  LD           DDAK    EEE  
Sbjct: 852  STPASLALPFVLILTVPLRRVLLPLIFRNVELQCLD----------ADDAKATFDEEEGR 901

Query: 1030 EKMLEI 1035
            ++  E+
Sbjct: 902  DEYDEV 907


>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
          Length = 891

 Score =  224 bits (572), Expect = 3e-58
 Identities = 184/673 (27%), Positives = 315/673 (46%), Gaps = 66/673 (9%)

Query: 338 RFLFILLGP--VGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTV 395
           RF+ ++L P  +   +   E+ R+ AT+ +D  F     + +  ++    +      +T+
Sbjct: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307

Query: 396 LPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSGPELQRTGRLFGGL 455
           +  G   P  +     ++P+               H   EP      P+ +       G+
Sbjct: 308 VSHGPVAPRTKERSTVSLPA---------------HRHPEP------PKCKDFVPFGKGI 346

Query: 456 VLDIKRKAPWYWSDYRDALSLQ------CLASFLFLYCACMSPVITFGGLLGEATEGRIS 509
             DI R+ P Y  D+ D +  +       + + LFLY AC+ P I FG L  E T+G I 
Sbjct: 347 REDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDENTDGAID 406

Query: 510 AIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGLW 569
             +++ G S+ G+ Y+LF+GQ L IL +T P+ ++ +++   C DY L + S  A  GLW
Sbjct: 407 VQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSFYAWTGLW 466

Query: 570 TAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQLD 629
            +F   +    + S ++    R TEE  A  I I F+ +A++  + +   Y  + H    
Sbjct: 467 NSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKY-YYGH---- 521

Query: 630 HLSLYYCRCTLPENPNNHTLQYWKDHNIVTAEVHWANLTVSECQEMHGEFMGS-----AC 684
           +L  Y+ + T                ++V+     A+L  S    ++  F+ S     + 
Sbjct: 522 YLDDYHTKRT---------------SSLVSLSGLGASLNASLHTALNASFLASPTELPSA 566

Query: 685 GHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLTIFTMVII 744
            H G  T  +   S ++   T  L  TL  FK S Y    VR ++SD A+ + +    +I
Sbjct: 567 THSGQATAVL---SLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCALPIAVLAFSLI 623

Query: 745 DFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILIFMDQQIT 804
               G    ++   S F+    +  + +  I       V  A+    L ++L F++Q + 
Sbjct: 624 S-SHGFREIEM---SKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLLSMLFFIEQNLV 679

Query: 805 AVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECS 864
           A ++N  E++L KG  YH DLL++AI+    S+ GLPW  AA   S  HV +L L  E  
Sbjct: 680 AALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLHVRALALVEERV 739

Query: 865 APGE-QPKFLGIREQRVTGLMIFVLMGCSVFMTAI-LKFIPMPVLYGVFLYMGVSSLQGI 922
             G      + ++E R+T L   VL+G S+ +  + L++IP PVLYG+FLY+ ++SL G 
Sbjct: 740 ENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLFLYIALTSLDGN 799

Query: 923 QFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASP---AAIVFP 979
           Q   R+ L        P   Y+R VP RK+H FT +Q+  L+LL     S      ++FP
Sbjct: 800 QLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGMSSLPYMKMIFP 859

Query: 980 MMVLALVFVRKVM 992
           ++++A++ +R ++
Sbjct: 860 LIMIAMIPIRYIL 872


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapiens]
          Length = 783

 Score = 35.0 bits (79), Expect = 0.39
 Identities = 31/93 (33%), Positives = 48/93 (51%), Gaps = 6/93 (6%)

Query: 998  KRELSWLDDLMPESKKKKLDDAKKKAKEEEEAEKMLEIGGDKFPLESRKLLSSPGKNISC 1057
            K E S +D   P+SKK K    K++  + + + K   +   K P+E +K++SS  K ++ 
Sbjct: 61   KAEPSEVDMNSPKSKKAK---KKEEPSQNDISPKTKSLRKKKEPIE-KKVVSSKTKKVTK 116

Query: 1058 RCDPSEINISDEMPKTTVWKALSMNSGNAKEKS 1090
              +PSE  I    PK  + K   MN G  +EKS
Sbjct: 117  NEEPSEEEIDAPKPK-KMKKEKEMN-GETREKS 147


>gi|239755074 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 160

 Score = 34.7 bits (78), Expect = 0.51
 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 401 WDPSIR--IEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSG 442
           WDP+    + PP+    +  R  PGV NG    +E++ HG H G
Sbjct: 9   WDPAQEGVVSPPRPARLKPDRAGPGVENGPSPGLERQTHGAHGG 52


>gi|239749600 PREDICTED: hypothetical protein XP_002347101 [Homo
           sapiens]
          Length = 160

 Score = 34.7 bits (78), Expect = 0.51
 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 401 WDPSIR--IEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSG 442
           WDP+    + PP+    +  R  PGV NG    +E++ HG H G
Sbjct: 9   WDPAQEGVVSPPRPARLKPDRAGPGVENGPSPGLERQTHGAHGG 52


>gi|239743867 PREDICTED: hypothetical protein XP_002342984 [Homo
           sapiens]
          Length = 160

 Score = 34.7 bits (78), Expect = 0.51
 Identities = 16/44 (36%), Positives = 23/44 (52%), Gaps = 2/44 (4%)

Query: 401 WDPSIR--IEPPKNVPSQEKRKMPGVPNGNVCHIEQEPHGGHSG 442
           WDP+    + PP+    +  R  PGV NG    +E++ HG H G
Sbjct: 9   WDPAQEGVVSPPRPARLKPDRAGPGVENGPSPGLERQTHGAHGG 52


>gi|27886561 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 1 [Homo sapiens]
          Length = 1075

 Score = 34.3 bits (77), Expect = 0.66
 Identities = 16/59 (27%), Positives = 27/59 (45%)

Query: 59  QSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELF 117
           Q   HHR H +    RG  K ++ G   ++ L ++     +Q  +GT +D    PH  +
Sbjct: 438 QPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFY 496


>gi|27886559 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 4 [Homo sapiens]
          Length = 1045

 Score = 34.3 bits (77), Expect = 0.66
 Identities = 16/59 (27%), Positives = 27/59 (45%)

Query: 59  QSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELF 117
           Q   HHR H +    RG  K ++ G   ++ L ++     +Q  +GT +D    PH  +
Sbjct: 438 QPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFY 496


>gi|27886555 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 3 [Homo sapiens]
          Length = 1065

 Score = 34.3 bits (77), Expect = 0.66
 Identities = 16/59 (27%), Positives = 27/59 (45%)

Query: 59  QSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELF 117
           Q   HHR H +    RG  K ++ G   ++ L ++     +Q  +GT +D    PH  +
Sbjct: 438 QPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFY 496


>gi|4758804 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 3 isoform 2 [Homo sapiens]
          Length = 1068

 Score = 34.3 bits (77), Expect = 0.66
 Identities = 16/59 (27%), Positives = 27/59 (45%)

Query: 59  QSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELF 117
           Q   HHR H +    RG  K ++ G   ++ L ++     +Q  +GT +D    PH  +
Sbjct: 438 QPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFY 496


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 34.3 bits (77), Expect = 0.66
 Identities = 17/69 (24%), Positives = 29/69 (42%)

Query: 49  YVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEED 108
           Y  + + +  Q   HHR H +    RG  K A  G   ++ L +      +Q  +GT ++
Sbjct: 477 YEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADE 536

Query: 109 EEHVPHELF 117
               PH  +
Sbjct: 537 RNLRPHAFY 545


>gi|27886563 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 2 [Homo sapiens]
          Length = 902

 Score = 34.3 bits (77), Expect = 0.66
 Identities = 17/69 (24%), Positives = 29/69 (42%)

Query: 49  YVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEED 108
           Y  + + +  Q   HHR H +    RG  K A  G   ++ L +      +Q  +GT ++
Sbjct: 414 YEQLELRIEVQPRAHHRAHYETEGSRGAVKAAPGGHPVVKLLGYSEKPLTLQMFIGTADE 473

Query: 109 EEHVPHELF 117
               PH  +
Sbjct: 474 RNLRPHAFY 482


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 31/112 (27%), Positives = 46/112 (41%), Gaps = 22/112 (19%)

Query: 38  EKEELEGHRTLYVGVRMPLGRQSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQ 97
           E+EE E   T Y       G Q+HRH            RG G+ + E+  +   H  PS 
Sbjct: 198 EEEEEEEASTEY-------GHQAHRH------------RGHGSEEDEDVSDGHHHHGPSH 238

Query: 98  RVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDG 149
           R Q   G EED++    +   + D+    E      +     ++ +EDV DG
Sbjct: 239 RHQ---GHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDG 287


>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
          Length = 569

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 10/94 (10%)

Query: 59  QSHRHHRTHGQKHRRRGRGKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHELFT 118
           Q  R HR H +  R+R R       E+  E +  +   ++ +     +E+EE    +   
Sbjct: 350 QEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKE----EKEEEEEEEMKQKE 405

Query: 119 ELDEICMKEGEDAEWKETARWLKFEEDVEDGGER 152
           E +EI  K  E+ E K+       E++ EDGG++
Sbjct: 406 EEEEIRNKNEEEGESKDE------EDEDEDGGQK 433


>gi|4557719 DNA ligase I [Homo sapiens]
          Length = 919

 Score = 33.1 bits (74), Expect = 1.5
 Identities = 21/55 (38%), Positives = 25/55 (45%)

Query: 106 EEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSKPYVAT 160
           EE+EE  P E  TE +    KEGED +   T          E   E  S+P VAT
Sbjct: 153 EEEEEETPKESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAETPTESVSEPEVAT 207


>gi|150378503 leiomodin 2 (cardiac) [Homo sapiens]
          Length = 547

 Score = 32.7 bits (73), Expect = 1.9
 Identities = 32/120 (26%), Positives = 47/120 (39%), Gaps = 15/120 (12%)

Query: 11  GVLSYQRPDEEAVVDQGGTSTILNIHYEKEELEGHRTLYVGVRM-------PLGRQSHRH 63
           G+  Y+  DE+ ++       +  +  E E++E  R L VG+R        P G  S   
Sbjct: 9   GLSKYESIDEDELLASLSAEELKELERELEDIEPDRNLPVGLRQKSLTEKTPTGTFSREA 68

Query: 64  HRTHGQKH-------RRRGR-GKGASQGEEGLEALAHDTPSQRVQFILGTEEDEEHVPHE 115
              + +K         R G  GK A   EE  E L     +  V   + TEE+EE    E
Sbjct: 69  LMAYWEKESQKLLEKERLGECGKVAEDKEESEEELIFTESNSEVSEEVYTEEEEEESQEE 128


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
            sapiens]
          Length = 929

 Score = 31.6 bits (70), Expect = 4.3
 Identities = 20/66 (30%), Positives = 33/66 (50%)

Query: 1010 ESKKKKLDDAKKKAKEEEEAEKMLEIGGDKFPLESRKLLSSPGKNISCRCDPSEINISDE 1069
            E +KKK    KKK KE+E+ +K  E   +K   E R+      K+   + +P  +  S  
Sbjct: 698  EKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPV 757

Query: 1070 MPKTTV 1075
            +P+ T+
Sbjct: 758  IPRLTL 763


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,899,884
Number of Sequences: 37866
Number of extensions: 2128248
Number of successful extensions: 6949
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 6812
Number of HSP's gapped (non-prelim): 86
length of query: 1093
length of database: 18,247,518
effective HSP length: 113
effective length of query: 980
effective length of database: 13,968,660
effective search space: 13689286800
effective search space used: 13689286800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.