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Search of human proteins with 8923904
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923904 bridging integrator 3 [Homo sapiens]
(253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923904 bridging integrator 3 [Homo sapiens] 498 e-141
gi|49472835 bridging integrator 2 [Homo sapiens] 62 4e-10
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens] 57 2e-08
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens] 57 2e-08
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens] 57 2e-08
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] 57 2e-08
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 57 2e-08
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] 57 2e-08
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens] 57 2e-08
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 51 8e-07
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 51 8e-07
gi|39930351 dynamin binding protein [Homo sapiens] 48 7e-06
gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens] 48 9e-06
gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens] 48 9e-06
gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens] 48 9e-06
gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 44 1e-04
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 44 1e-04
gi|55770834 centromere protein F [Homo sapiens] 43 2e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 42 5e-04
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 42 5e-04
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 42 5e-04
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 42 5e-04
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 42 5e-04
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 42 5e-04
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 42 5e-04
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 42 5e-04
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 42 5e-04
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 42 5e-04
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 42 5e-04
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 41 9e-04
>gi|8923904 bridging integrator 3 [Homo sapiens]
Length = 253
Score = 498 bits (1282), Expect = e-141
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MSWIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAV 60
MSWIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAV
Sbjct: 1 MSWIPFKIGQPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAV 60
Query: 61 KISLDLLSNPLCEQDQDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPS 120
KISLDLLSNPLCEQDQDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPS
Sbjct: 61 KISLDLLSNPLCEQDQDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPS 120
Query: 121 LNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLL 180
LNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLL
Sbjct: 121 LNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLL 180
Query: 181 EEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAK 240
EEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAK
Sbjct: 181 EEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAK 240
Query: 241 LSELRALSIVADD 253
LSELRALSIVADD
Sbjct: 241 LSELRALSIVADD 253
>gi|49472835 bridging integrator 2 [Homo sapiens]
Length = 565
Score = 62.4 bits (150), Expect = 4e-10
Identities = 46/198 (23%), Positives = 88/198 (44%), Gaps = 7/198 (3%)
Query: 18 KTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQD 77
+T + FE+ Q + + +L KD+K A M +S+ ++S L E D
Sbjct: 37 ETKDERFEQSASNFYQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGH 96
Query: 78 LLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRR 137
L + D ++ ++ + ++ + + F + + +R + L DY
Sbjct: 97 -----EELKAIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYDS 151
Query: 138 LQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPS 197
+ +E + +K AK +A EE + FE N++LLEE+P Y SR+ +
Sbjct: 152 ARHHLEAVQNAKKKDE--AKTAKAEEEFNKAQTVFEDLNQELLEELPILYNSRIGCYVTI 209
Query: 198 FESLIRAQVVYYSEMHKI 215
F+++ + V+Y EM K+
Sbjct: 210 FQNISNLRDVFYREMSKL 227
>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
Length = 409
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY + E +
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
+K AK+ +A EEL ++ FE N L EE+P + SR+ ++ +F+S+ + +
Sbjct: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
Query: 209 YSEMHKIFGDLSHQL 223
+ EM K+ +L+ L
Sbjct: 222 HKEMSKLNQNLNDVL 236
>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
Length = 439
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY + E +
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
+K AK+ +A EEL ++ FE N L EE+P + SR+ ++ +F+S+ + +
Sbjct: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
Query: 209 YSEMHKIFGDLSHQL 223
+ EM K+ +L+ L
Sbjct: 222 HKEMSKLNQNLNDVL 236
>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
Length = 475
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY + E +
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
+K AK+ +A EEL ++ FE N L EE+P + SR+ ++ +F+S+ + +
Sbjct: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
Query: 209 YSEMHKIFGDLSHQL 223
+ EM K+ +L+ L
Sbjct: 222 HKEMSKLNQNLNDVL 236
>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
Length = 482
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY + E +
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
+K AK+ +A EEL ++ FE N L EE+P + SR+ ++ +F+S+ + +
Sbjct: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
Query: 209 YSEMHKIFGDLSHQL 223
+ EM K+ +L+ L
Sbjct: 222 HKEMSKLNQNLNDVL 236
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY + E +
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
+K AK+ +A EEL ++ FE N L EE+P + SR+ ++ +F+S+ + +
Sbjct: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
Query: 209 YSEMHKIFGDLSHQL 223
+ EM K+ +L+ L
Sbjct: 222 HKEMSKLNQNLNDVL 236
>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
Length = 497
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY + E +
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
+K AK+ +A EEL ++ FE N L EE+P + SR+ ++ +F+S+ + +
Sbjct: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
Query: 209 YSEMHKIFGDLSHQL 223
+ EM K+ +L+ L
Sbjct: 222 HKEMSKLNQNLNDVL 236
>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
Length = 454
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/195 (28%), Positives = 100/195 (51%), Gaps = 14/195 (7%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEK 148
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY + E +
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
+K AK+ +A EEL ++ FE N L EE+P + SR+ ++ +F+S+ + +
Sbjct: 164 KKKDE--AKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF 221
Query: 209 YSEMHKIFGDLSHQL 223
+ EM K+ +L+ L
Sbjct: 222 HKEMSKLNQNLNDVL 236
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 51.2 bits (121), Expect = 8e-07
Identities = 46/220 (20%), Positives = 104/220 (47%), Gaps = 17/220 (7%)
Query: 18 KTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKI--SLDLLSNPLCEQD 75
+T + FE ++ E + RLQ++++ A M ++++K+ SL + P
Sbjct: 33 ETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGR 92
Query: 76 QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY 135
+D+ + D + F+Q+ V+ T L + FP + + +R + L DY
Sbjct: 93 EDVKMVGEKCDVL---WEDFHQKLVDGSLLT----LDTYLGQFPDIKNRIAKRSRKLVDY 145
Query: 136 RRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQ 195
+ +E + ++ +++ +A EE + ++ FE N L EE+P + R+ ++
Sbjct: 146 DSARHHLEALQSSKRKDE--SRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYV 203
Query: 196 PSFESLIRAQVVYYSEM----HKIFGDLSHQLDQPGHSDE 231
+F+++ + ++ E+ HK++ ++ DQ H+D+
Sbjct: 204 NTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQ--HADK 241
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 51.2 bits (121), Expect = 8e-07
Identities = 46/220 (20%), Positives = 104/220 (47%), Gaps = 17/220 (7%)
Query: 18 KTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKI--SLDLLSNPLCEQD 75
+T + FE ++ E + RLQ++++ A M ++++K+ SL + P
Sbjct: 33 ETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGR 92
Query: 76 QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY 135
+D+ + D + F+Q+ V+ T L + FP + + +R + L DY
Sbjct: 93 EDVKMVGEKCDVL---WEDFHQKLVDGSLLT----LDTYLGQFPDIKNRIAKRSRKLVDY 145
Query: 136 RRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQ 195
+ +E + ++ +++ +A EE + ++ FE N L EE+P + R+ ++
Sbjct: 146 DSARHHLEALQSSKRKDE--SRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYV 203
Query: 196 PSFESLIRAQVVYYSEM----HKIFGDLSHQLDQPGHSDE 231
+F+++ + ++ E+ HK++ ++ DQ H+D+
Sbjct: 204 NTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQ--HADK 241
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 48.1 bits (113), Expect = 7e-06
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 19/110 (17%)
Query: 104 QKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQARE 163
++ VI PL + S+F + V++R L D+ + EK ++K+ E
Sbjct: 1100 ERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTL-----------E 1148
Query: 164 ELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMH 213
EL+ R ++EA N QLL+E+P+F+ Y Q F + + Y+E H
Sbjct: 1149 ELQSARNNYEALNAQLLDELPKFH----QYAQGLFTNCVHG----YAEAH 1190
>gi|21536404 bridging integrator 1 isoform 3 [Homo sapiens]
Length = 506
Score = 47.8 bits (112), Expect = 9e-06
Identities = 60/224 (26%), Positives = 103/224 (45%), Gaps = 41/224 (18%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY-------RRLQAK 141
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY LQ
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 142 VEKYEEK--------EKTGPVLAK--------------LHQAREELRPVREDFEAKNRQL 179
+K E K EK P + +QA EEL ++ FE N L
Sbjct: 164 KKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDL 223
Query: 180 LEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQL 223
EE+P + SR+ ++ +F+S+ + ++ EM K+ +L+ L
Sbjct: 224 QEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVL 267
>gi|21536402 bridging integrator 1 isoform 2 [Homo sapiens]
Length = 550
Score = 47.8 bits (112), Expect = 9e-06
Identities = 60/224 (26%), Positives = 103/224 (45%), Gaps = 41/224 (18%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY-------RRLQAK 141
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY LQ
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 142 VEKYEEK--------EKTGPVLAK--------------LHQAREELRPVREDFEAKNRQL 179
+K E K EK P + +QA EEL ++ FE N L
Sbjct: 164 KKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDL 223
Query: 180 LEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQL 223
EE+P + SR+ ++ +F+S+ + ++ EM K+ +L+ L
Sbjct: 224 QEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVL 267
>gi|21536400 bridging integrator 1 isoform 1 [Homo sapiens]
Length = 593
Score = 47.8 bits (112), Expect = 9e-06
Identities = 60/224 (26%), Positives = 103/224 (45%), Gaps = 41/224 (18%)
Query: 32 QQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQD---QDLLNMVTALDTA 88
+QL E TR LQKD++ + AM +++ K++ L + E D +D N + A +
Sbjct: 53 KQLTEGTR-LQKDLRTYLASVKAMHEASKKLNECL--QEVYEPDWPGRDEANKI-AENND 108
Query: 89 MKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY-------RRLQAK 141
+ MD ++Q+ V+Q T+ L +F P + + +R + L DY LQ
Sbjct: 109 LLWMD-YHQKLVDQALLTMDTYLGQF----PDIKSRIAKRGRKLVDYDSARHHYESLQTA 163
Query: 142 VEKYEEK--------EKTGPVLAK--------------LHQAREELRPVREDFEAKNRQL 179
+K E K EK P + +QA EEL ++ FE N L
Sbjct: 164 KKKDEAKIAKPVSLLEKAAPQWCQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEEMNVDL 223
Query: 180 LEEMPRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQL 223
EE+P + SR+ ++ +F+S+ + ++ EM K+ +L+ L
Sbjct: 224 QEELPSLWNSRVGFYVNTFQSIAGLEENFHKEMSKLNQNLNDVL 267
>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
Length = 2028
Score = 44.3 bits (103), Expect = 1e-04
Identities = 49/203 (24%), Positives = 95/203 (46%), Gaps = 20/203 (9%)
Query: 18 KTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQD 77
K + + GKL QLE + R+L +D++++ + + A K+ +L L E++
Sbjct: 593 KALHQTVTEANGKLSQLEFEKRQLHRDLEQAKE----KGERAEKLEREL--QRLQEENGR 646
Query: 78 LLNMVTALDTAMKRMDAFNQEK--VNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDY 135
L VT+L+TA ++++A E + +T+ + L +V SL + R+ D
Sbjct: 647 LARKVTSLETATEKVEALEHESQGLQLENRTLRKSLDTLQNV--SLQLEGLERDNKQLDA 704
Query: 136 RRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQ 195
L+ + E T LA++ + ++L +E+ KN LL+ + G + + +
Sbjct: 705 ENLELR-RLVETMRFTSTKLAQMERENQQLEREKEELR-KNVDLLKAL----GKKSERLE 758
Query: 196 PSFESL----IRAQVVYYSEMHK 214
S++S+ +R Q S HK
Sbjct: 759 LSYQSVSAENLRLQQSLESSSHK 781
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 43.9 bits (102), Expect = 1e-04
Identities = 51/221 (23%), Positives = 96/221 (43%), Gaps = 25/221 (11%)
Query: 22 RDFEREYGKLQQLEEQTRRLQK---DMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDL 78
RD ER + L+++ R K + K+ D A ++A K S L + +L
Sbjct: 1434 RDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLST--------EL 1485
Query: 79 LNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRL 138
M A + + +++ +E N +Q+ + + ++ +L A K ++ Q+ L
Sbjct: 1486 FKMRNAYEEVVDQLETLRRENKN-LQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDL 1544
Query: 139 QAKVEKYE-----EKEKTGPVLAKLHQAREEL--RPVREDFEAKNRQLLEEMPRFYGSRL 191
Q +E+ E E+ K V +L Q + EL + + +D E +E++ R
Sbjct: 1545 QVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEE------IEQLKRNSQRAA 1598
Query: 192 DYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQ 232
+ Q ++ IR++ K+ GDL+ Q GHS+ Q
Sbjct: 1599 EALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQ 1639
Score = 31.2 bits (69), Expect = 0.91
Identities = 35/160 (21%), Positives = 70/160 (43%), Gaps = 10/160 (6%)
Query: 20 VERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLL 79
+E E+E LE R+L+ D+K S ++ + + +I L +++ +L
Sbjct: 1038 LEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQI-----EEKLKKKEFELS 1092
Query: 80 NMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQ 139
+ +D F Q+K+ ++Q IE L++ +L ++++ L R L+
Sbjct: 1093 QLQAKIDDEQVHSLQF-QKKIKELQAR-IEELEEEIEAEHTLRAKIEKQRSDLA--RELE 1148
Query: 140 AKVEKYEEKEKTGPVLAKLHQARE-ELRPVREDFEAKNRQ 178
E+ EE ++++ RE E + +R D E Q
Sbjct: 1149 EISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1188
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 43.1 bits (100), Expect = 2e-04
Identities = 42/187 (22%), Positives = 86/187 (45%), Gaps = 17/187 (9%)
Query: 12 KKQIVPKTVERDFEREYG-KLQQLEEQTRRLQKDMKKSTDADLAMSK----------SAV 60
K Q+ + R+ EY +L + E++ + L D K + ++ + S+
Sbjct: 2683 KDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQ 2742
Query: 61 KISLDLLSNPLCEQDQDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPS 120
K+ +DLL + E+ + L T + +K+ N + VNQ++K K + S
Sbjct: 2743 KLEIDLLKSSK-EELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKS 2801
Query: 121 LNMAVKRREQALQDYRRLQAKVEKYEEKEKTGPVL-AKLHQAREELRPVREDFEAKNRQL 179
+ +E ++ +LQA +EK+KTG V+ K+ + E++ ++E E K ++
Sbjct: 2802 CKQLEEEKEILQKELSQLQAA----QEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEA 2857
Query: 180 LEEMPRF 186
E + ++
Sbjct: 2858 DEYLDKY 2864
Score = 35.0 bits (79), Expect = 0.063
Identities = 41/178 (23%), Positives = 83/178 (46%), Gaps = 27/178 (15%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVK----ISLDLLSNPLC-EQDQDLL 79
E+ + Q E + RR ++MKK + + S+ + + +L + C Q Q+
Sbjct: 464 EQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFA 523
Query: 80 NMVTALDTAMKRMDAFNQEKVNQIQ--------KTVIEPLKKFGSVFPSLNMAVKRREQA 131
+ A +T+ + M QEK+NQ + K + L+K L +K+RE
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDL---LKKREHH 580
Query: 132 LQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVRED------FEAKNRQLLEEM 183
++ +L K+ K E++ K +L+ L ++E ++E+ ++++N +LL +M
Sbjct: 581 IE---QLNDKLSKTEKESKA--LLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQM 633
Score = 33.1 bits (74), Expect = 0.24
Identities = 53/238 (22%), Positives = 102/238 (42%), Gaps = 33/238 (13%)
Query: 30 KLQQLEEQTRRLQ--KDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTALDT 87
KLQ LE+ ++ L K ++ A L K + + L L E D + LN+ AL+
Sbjct: 2036 KLQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEA 2095
Query: 88 AMKRMDAF------NQEKVNQIQKTV------IEPLKKFGSVFPSLNMAVKRREQALQDY 135
A+ F QE+V+Q+++ + IE +K L++A K +E+ ++
Sbjct: 2096 ALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEK-----KQLHIAEKLKERE-REN 2149
Query: 136 RRLQAKVEKYE-----EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSR 190
L+ KVE E +E V+ ++ E+ ++ E R L + +
Sbjct: 2150 DSLKDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSL-----KVFELD 2204
Query: 191 LDYFQPSFESL---IRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSELR 245
L + E+L I+ + SE+ K+ L++ ++ Q + E++ + L+
Sbjct: 2205 LVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQ 2262
Score = 32.0 bits (71), Expect = 0.53
Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 14/185 (7%)
Query: 20 VERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLL 79
+ RDF Y +Q +R + K+ ++ + S+ + LD L Q+Q+L
Sbjct: 237 IRRDFSASYFSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHL-LDQLK----AQNQELR 291
Query: 80 NMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQ 139
N + L+ ++ + + +VN+ Q+ ++ K + + K R++ ++ +
Sbjct: 292 NKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYD 351
Query: 140 AKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKN---RQLLEEMPRFYGSRLDYFQP 196
KY E+ KL + E+L R++ E+ Q ++E + + L Q
Sbjct: 352 QASTKYTALEQ------KLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQR 405
Query: 197 SFESL 201
SF++L
Sbjct: 406 SFQTL 410
Score = 29.3 bits (64), Expect = 3.4
Identities = 32/174 (18%), Positives = 72/174 (41%), Gaps = 20/174 (11%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E ++Q+L++ L+ +K +L + + + +S+ + +++ +
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLK-----ELQLLSETLSLEKKEMSSIISLNKREIEELTQE 975
Query: 85 LDTAMKRMDAFNQEKVNQIQKT------VIEPLKKFGSVFPSLN----MAVKRREQALQD 134
T + + NQEK+N IQK+ + E K + + ++R E+
Sbjct: 976 NGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNA 1035
Query: 135 YRRLQAKVEKYEEKEKTGPVL-----AKLHQAREELRPVREDFEAKNRQLLEEM 183
Y L K + +EK L + + EL ++E F ++++ L ++
Sbjct: 1036 YEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKL 1089
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 42.0 bits (97), Expect = 5e-04
Identities = 38/162 (23%), Positives = 80/162 (49%), Gaps = 16/162 (9%)
Query: 33 QLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTALDTAMKRM 92
QL+E R L++ ++ D A+ + + + D + L +Q +DL + + A D + + +
Sbjct: 972 QLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMD--LQKQVEDLKSQLVAQDDSQRLV 1029
Query: 93 DAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQAL-----------QDYRRLQAK 141
+ QEK+ + Q+ K+ SL +++ +EQ L Q+ L+
Sbjct: 1030 EQEVQEKLRETQE-YNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQD 1088
Query: 142 VEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
+++ + ++K + A++ R+E++ DF A+ QLLEE+
Sbjct: 1089 MQEAQGEQKE--LSAQMELLRQEVKEKEADFLAQEAQLLEEL 1128
Score = 38.9 bits (89), Expect = 0.004
Identities = 46/215 (21%), Positives = 90/215 (41%), Gaps = 24/215 (11%)
Query: 34 LEEQTRRLQKD---MKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTALDTAMK 90
LE+Q +K+ +++ + + + + + +L+ L E + L T ++
Sbjct: 844 LEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQA 903
Query: 91 RMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQA--KVEKYEEK 148
+ + + + + + +E K+ S+ +L K A Q RL+ KV+K +E+
Sbjct: 904 QREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQ 963
Query: 149 EKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRAQVVY 208
E TG + +L +A+ EL+ E R + L Q SL++ ++
Sbjct: 964 ETTGILQTQLQEAQRELK---------------EAARQHRDDLAALQEESSSLLQDKM-- 1006
Query: 209 YSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
++ K DL QL S E+E + KL E
Sbjct: 1007 --DLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRE 1039
Score = 37.7 bits (86), Expect = 0.010
Identities = 35/133 (26%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
Query: 30 KLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDL---------LN 80
K +++E + R Q +++ + +A K A++ +L LL+ L E+++++ L
Sbjct: 1391 KNEEVESERERAQA-LQEQGELKVAQGK-ALQENLALLTQTLAEREEEVETLRGQIQELE 1448
Query: 81 MVTALDTAMKRMDAFNQEKVNQ---IQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRR 137
+ A + + + +K NQ +Q+ I+ L+K SV L MAV+ REQ L R
Sbjct: 1449 KQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQRE 1508
Query: 138 LQAKVEKYEEKEK 150
++EK E ++
Sbjct: 1509 QIRELEKDRETQR 1521
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 42.0 bits (97), Expect = 5e-04
Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 10/132 (7%)
Query: 22 RDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKI---SLDLLSNPLCEQDQDL 78
++++ E L+Q +E+ + +D S +A L SK VK LD L N L E + +L
Sbjct: 65 KEYQMELKYLKQYKEKACEI-RDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNL 123
Query: 79 L------NMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQAL 132
N + ALD+ K+M+ N E +++K ++ ++ + V+ +E+ L
Sbjct: 124 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKL 183
Query: 133 QDYRRLQAKVEK 144
D R K+ K
Sbjct: 184 VDCHRELEKLNK 195
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 42.0 bits (97), Expect = 5e-04
Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 10/132 (7%)
Query: 22 RDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKI---SLDLLSNPLCEQDQDL 78
++++ E L+Q +E+ + +D S +A L SK VK LD L N L E + +L
Sbjct: 204 KEYQMELKYLKQYKEKACEI-RDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNL 262
Query: 79 L------NMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQAL 132
N + ALD+ K+M+ N E +++K ++ ++ + V+ +E+ L
Sbjct: 263 SKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKL 322
Query: 133 QDYRRLQAKVEK 144
D R K+ K
Sbjct: 323 VDCHRELEKLNK 334
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/244 (21%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 10 QPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLL-- 67
Q +K++ + R E + QQL E+T+ Q+ ++ L MS A ++ L +
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2392
Query: 68 --SNPLCEQD-QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMA 124
+ E+D Q + + R + QEKV +Q I+
Sbjct: 2393 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ--------------- 2437
Query: 125 VKRREQALQDYRRLQAKVEKYE-EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
R+Q+ D RL+ + + E EKEK L EE++ V+++ QLL+E
Sbjct: 2438 ---RQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQE------QLLQET 2488
Query: 184 PRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
S F +SL++ + E K+ ++ + E+++R+ + E
Sbjct: 2489 QALQQS----FLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Query: 244 LRAL 247
+ L
Sbjct: 2545 RQRL 2548
Score = 32.7 bits (73), Expect = 0.31
Identities = 39/220 (17%), Positives = 89/220 (40%), Gaps = 18/220 (8%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E + +QL + R +++ ++ LA + A + L +++ +
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL--------EEVERLKAK 2017
Query: 85 LDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEK 144
++ A + + QE Q+Q K+ + + AV+++EQ LQ + LQ +
Sbjct: 2018 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ--QTLQQEQSV 2075
Query: 145 YEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRA 204
++ + + EE R E A++R+ +EE R + S E +A
Sbjct: 2076 LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER--------LKQSAEEQAQA 2127
Query: 205 QVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
+ + K+ + + + +++ R+ +A +E+
Sbjct: 2128 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Score = 31.2 bits (69), Expect = 0.91
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 9/62 (14%)
Query: 125 VKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMP 184
+K + QA+Q+ RL+A+ E +++++ A+E+ R ++ED E +QL EE
Sbjct: 2312 LKEKMQAVQEATRLKAEAELLQQQKEL---------AQEQARRLQEDKEQMAQQLAEETQ 2362
Query: 185 RF 186
F
Sbjct: 2363 GF 2364
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/244 (21%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 10 QPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLL-- 67
Q +K++ + R E + QQL E+T+ Q+ ++ L MS A ++ L +
Sbjct: 2337 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2396
Query: 68 --SNPLCEQD-QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMA 124
+ E+D Q + + R + QEKV +Q I+
Sbjct: 2397 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ--------------- 2441
Query: 125 VKRREQALQDYRRLQAKVEKYE-EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
R+Q+ D RL+ + + E EKEK L EE++ V+++ QLL+E
Sbjct: 2442 ---RQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQE------QLLQET 2492
Query: 184 PRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
S F +SL++ + E K+ ++ + E+++R+ + E
Sbjct: 2493 QALQQS----FLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2548
Query: 244 LRAL 247
+ L
Sbjct: 2549 RQRL 2552
Score = 32.7 bits (73), Expect = 0.31
Identities = 39/220 (17%), Positives = 89/220 (40%), Gaps = 18/220 (8%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E + +QL + R +++ ++ LA + A + L +++ +
Sbjct: 1970 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL--------EEVERLKAK 2021
Query: 85 LDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEK 144
++ A + + QE Q+Q K+ + + AV+++EQ LQ + LQ +
Sbjct: 2022 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ--QTLQQEQSV 2079
Query: 145 YEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRA 204
++ + + EE R E A++R+ +EE R + S E +A
Sbjct: 2080 LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER--------LKQSAEEQAQA 2131
Query: 205 QVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
+ + K+ + + + +++ R+ +A +E+
Sbjct: 2132 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2171
Score = 31.2 bits (69), Expect = 0.91
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 9/62 (14%)
Query: 125 VKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMP 184
+K + QA+Q+ RL+A+ E +++++ A+E+ R ++ED E +QL EE
Sbjct: 2316 LKEKMQAVQEATRLKAEAELLQQQKEL---------AQEQARRLQEDKEQMAQQLAEETQ 2366
Query: 185 RF 186
F
Sbjct: 2367 GF 2368
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/244 (21%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 10 QPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLL-- 67
Q +K++ + R E + QQL E+T+ Q+ ++ L MS A ++ L +
Sbjct: 2333 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2392
Query: 68 --SNPLCEQD-QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMA 124
+ E+D Q + + R + QEKV +Q I+
Sbjct: 2393 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ--------------- 2437
Query: 125 VKRREQALQDYRRLQAKVEKYE-EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
R+Q+ D RL+ + + E EKEK L EE++ V+++ QLL+E
Sbjct: 2438 ---RQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQE------QLLQET 2488
Query: 184 PRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
S F +SL++ + E K+ ++ + E+++R+ + E
Sbjct: 2489 QALQQS----FLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Query: 244 LRAL 247
+ L
Sbjct: 2545 RQRL 2548
Score = 32.7 bits (73), Expect = 0.31
Identities = 39/220 (17%), Positives = 89/220 (40%), Gaps = 18/220 (8%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E + +QL + R +++ ++ LA + A + L +++ +
Sbjct: 1966 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL--------EEVERLKAK 2017
Query: 85 LDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEK 144
++ A + + QE Q+Q K+ + + AV+++EQ LQ + LQ +
Sbjct: 2018 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ--QTLQQEQSV 2075
Query: 145 YEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRA 204
++ + + EE R E A++R+ +EE R + S E +A
Sbjct: 2076 LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER--------LKQSAEEQAQA 2127
Query: 205 QVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
+ + K+ + + + +++ R+ +A +E+
Sbjct: 2128 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2167
Score = 31.2 bits (69), Expect = 0.91
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 9/62 (14%)
Query: 125 VKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMP 184
+K + QA+Q+ RL+A+ E +++++ A+E+ R ++ED E +QL EE
Sbjct: 2312 LKEKMQAVQEATRLKAEAELLQQQKEL---------AQEQARRLQEDKEQMAQQLAEETQ 2362
Query: 185 RF 186
F
Sbjct: 2363 GF 2364
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/244 (21%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 10 QPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLL-- 67
Q +K++ + R E + QQL E+T+ Q+ ++ L MS A ++ L +
Sbjct: 2301 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2360
Query: 68 --SNPLCEQD-QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMA 124
+ E+D Q + + R + QEKV +Q I+
Sbjct: 2361 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ--------------- 2405
Query: 125 VKRREQALQDYRRLQAKVEKYE-EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
R+Q+ D RL+ + + E EKEK L EE++ V+++ QLL+E
Sbjct: 2406 ---RQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQE------QLLQET 2456
Query: 184 PRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
S F +SL++ + E K+ ++ + E+++R+ + E
Sbjct: 2457 QALQQS----FLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2512
Query: 244 LRAL 247
+ L
Sbjct: 2513 RQRL 2516
Score = 32.7 bits (73), Expect = 0.31
Identities = 39/220 (17%), Positives = 89/220 (40%), Gaps = 18/220 (8%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E + +QL + R +++ ++ LA + A + L +++ +
Sbjct: 1934 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL--------EEVERLKAK 1985
Query: 85 LDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEK 144
++ A + + QE Q+Q K+ + + AV+++EQ LQ + LQ +
Sbjct: 1986 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ--QTLQQEQSV 2043
Query: 145 YEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRA 204
++ + + EE R E A++R+ +EE R + S E +A
Sbjct: 2044 LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER--------LKQSAEEQAQA 2095
Query: 205 QVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
+ + K+ + + + +++ R+ +A +E+
Sbjct: 2096 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2135
Score = 31.2 bits (69), Expect = 0.91
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 9/62 (14%)
Query: 125 VKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMP 184
+K + QA+Q+ RL+A+ E +++++ A+E+ R ++ED E +QL EE
Sbjct: 2280 LKEKMQAVQEATRLKAEAELLQQQKEL---------AQEQARRLQEDKEQMAQQLAEETQ 2330
Query: 185 RF 186
F
Sbjct: 2331 GF 2332
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/244 (21%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 10 QPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLL-- 67
Q +K++ + R E + QQL E+T+ Q+ ++ L MS A ++ L +
Sbjct: 2470 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2529
Query: 68 --SNPLCEQD-QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMA 124
+ E+D Q + + R + QEKV +Q I+
Sbjct: 2530 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ--------------- 2574
Query: 125 VKRREQALQDYRRLQAKVEKYE-EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
R+Q+ D RL+ + + E EKEK L EE++ V+++ QLL+E
Sbjct: 2575 ---RQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQE------QLLQET 2625
Query: 184 PRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
S F +SL++ + E K+ ++ + E+++R+ + E
Sbjct: 2626 QALQQS----FLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2681
Query: 244 LRAL 247
+ L
Sbjct: 2682 RQRL 2685
Score = 32.7 bits (73), Expect = 0.31
Identities = 39/220 (17%), Positives = 89/220 (40%), Gaps = 18/220 (8%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E + +QL + R +++ ++ LA + A + L +++ +
Sbjct: 2103 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL--------EEVERLKAK 2154
Query: 85 LDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEK 144
++ A + + QE Q+Q K+ + + AV+++EQ LQ + LQ +
Sbjct: 2155 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ--QTLQQEQSV 2212
Query: 145 YEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRA 204
++ + + EE R E A++R+ +EE R + S E +A
Sbjct: 2213 LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER--------LKQSAEEQAQA 2264
Query: 205 QVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
+ + K+ + + + +++ R+ +A +E+
Sbjct: 2265 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2304
Score = 31.2 bits (69), Expect = 0.91
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 9/62 (14%)
Query: 125 VKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMP 184
+K + QA+Q+ RL+A+ E +++++ A+E+ R ++ED E +QL EE
Sbjct: 2449 LKEKMQAVQEATRLKAEAELLQQQKEL---------AQEQARRLQEDKEQMAQQLAEETQ 2499
Query: 185 RF 186
F
Sbjct: 2500 GF 2501
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/244 (21%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 10 QPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLL-- 67
Q +K++ + R E + QQL E+T+ Q+ ++ L MS A ++ L +
Sbjct: 2311 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2370
Query: 68 --SNPLCEQD-QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMA 124
+ E+D Q + + R + QEKV +Q I+
Sbjct: 2371 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ--------------- 2415
Query: 125 VKRREQALQDYRRLQAKVEKYE-EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
R+Q+ D RL+ + + E EKEK L EE++ V+++ QLL+E
Sbjct: 2416 ---RQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQE------QLLQET 2466
Query: 184 PRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
S F +SL++ + E K+ ++ + E+++R+ + E
Sbjct: 2467 QALQQS----FLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2522
Query: 244 LRAL 247
+ L
Sbjct: 2523 RQRL 2526
Score = 32.7 bits (73), Expect = 0.31
Identities = 39/220 (17%), Positives = 89/220 (40%), Gaps = 18/220 (8%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E + +QL + R +++ ++ LA + A + L +++ +
Sbjct: 1944 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL--------EEVERLKAK 1995
Query: 85 LDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEK 144
++ A + + QE Q+Q K+ + + AV+++EQ LQ + LQ +
Sbjct: 1996 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ--QTLQQEQSV 2053
Query: 145 YEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRA 204
++ + + EE R E A++R+ +EE R + S E +A
Sbjct: 2054 LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER--------LKQSAEEQAQA 2105
Query: 205 QVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
+ + K+ + + + +++ R+ +A +E+
Sbjct: 2106 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2145
Score = 31.2 bits (69), Expect = 0.91
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 9/62 (14%)
Query: 125 VKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMP 184
+K + QA+Q+ RL+A+ E +++++ A+E+ R ++ED E +QL EE
Sbjct: 2290 LKEKMQAVQEATRLKAEAELLQQQKEL---------AQEQARRLQEDKEQMAQQLAEETQ 2340
Query: 185 RF 186
F
Sbjct: 2341 GF 2342
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/244 (21%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 10 QPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLL-- 67
Q +K++ + R E + QQL E+T+ Q+ ++ L MS A ++ L +
Sbjct: 2319 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2378
Query: 68 --SNPLCEQD-QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMA 124
+ E+D Q + + R + QEKV +Q I+
Sbjct: 2379 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ--------------- 2423
Query: 125 VKRREQALQDYRRLQAKVEKYE-EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
R+Q+ D RL+ + + E EKEK L EE++ V+++ QLL+E
Sbjct: 2424 ---RQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQE------QLLQET 2474
Query: 184 PRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
S F +SL++ + E K+ ++ + E+++R+ + E
Sbjct: 2475 QALQQS----FLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2530
Query: 244 LRAL 247
+ L
Sbjct: 2531 RQRL 2534
Score = 32.7 bits (73), Expect = 0.31
Identities = 39/220 (17%), Positives = 89/220 (40%), Gaps = 18/220 (8%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E + +QL + R +++ ++ LA + A + L +++ +
Sbjct: 1952 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL--------EEVERLKAK 2003
Query: 85 LDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEK 144
++ A + + QE Q+Q K+ + + AV+++EQ LQ + LQ +
Sbjct: 2004 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ--QTLQQEQSV 2061
Query: 145 YEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRA 204
++ + + EE R E A++R+ +EE R + S E +A
Sbjct: 2062 LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER--------LKQSAEEQAQA 2113
Query: 205 QVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
+ + K+ + + + +++ R+ +A +E+
Sbjct: 2114 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2153
Score = 31.2 bits (69), Expect = 0.91
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 9/62 (14%)
Query: 125 VKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMP 184
+K + QA+Q+ RL+A+ E +++++ A+E+ R ++ED E +QL EE
Sbjct: 2298 LKEKMQAVQEATRLKAEAELLQQQKEL---------AQEQARRLQEDKEQMAQQLAEETQ 2348
Query: 185 RF 186
F
Sbjct: 2349 GF 2350
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 42.0 bits (97), Expect = 5e-04
Identities = 53/244 (21%), Positives = 98/244 (40%), Gaps = 34/244 (13%)
Query: 10 QPKKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLL-- 67
Q +K++ + R E + QQL E+T+ Q+ ++ L MS A ++ L +
Sbjct: 2360 QQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEM 2419
Query: 68 --SNPLCEQD-QDLLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMA 124
+ E+D Q + + R + QEKV +Q I+
Sbjct: 2420 SRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ--------------- 2464
Query: 125 VKRREQALQDYRRLQAKVEKYE-EKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEM 183
R+Q+ D RL+ + + E EKEK L EE++ V+++ QLL+E
Sbjct: 2465 ---RQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQE------QLLQET 2515
Query: 184 PRFYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSE 243
S F +SL++ + E K+ ++ + E+++R+ + E
Sbjct: 2516 QALQQS----FLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2571
Query: 244 LRAL 247
+ L
Sbjct: 2572 RQRL 2575
Score = 32.7 bits (73), Expect = 0.31
Identities = 39/220 (17%), Positives = 89/220 (40%), Gaps = 18/220 (8%)
Query: 25 EREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQDLLNMVTA 84
E E + +QL + R +++ ++ LA + A + L +++ +
Sbjct: 1993 ELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAAL--------EEVERLKAK 2044
Query: 85 LDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRRLQAKVEK 144
++ A + + QE Q+Q K+ + + AV+++EQ LQ + LQ +
Sbjct: 2045 VEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQ--QTLQQEQSV 2102
Query: 145 YEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRFYGSRLDYFQPSFESLIRA 204
++ + + EE R E A++R+ +EE R + S E +A
Sbjct: 2103 LDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAER--------LKQSAEEQAQA 2154
Query: 205 QVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
+ + K+ + + + +++ R+ +A +E+
Sbjct: 2155 RAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEM 2194
Score = 31.2 bits (69), Expect = 0.91
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 9/62 (14%)
Query: 125 VKRREQALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMP 184
+K + QA+Q+ RL+A+ E +++++ A+E+ R ++ED E +QL EE
Sbjct: 2339 LKEKMQAVQEATRLKAEAELLQQQKEL---------AQEQARRLQEDKEQMAQQLAEETQ 2389
Query: 185 RF 186
F
Sbjct: 2390 GF 2391
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 41.2 bits (95), Expect = 9e-04
Identities = 56/239 (23%), Positives = 99/239 (41%), Gaps = 42/239 (17%)
Query: 22 RDFEREYGKLQQLEEQTRRLQKDMKKST---DADLAMSKSAVKISLDLLSNPLCEQDQDL 78
R E E LQ+ +E+ +K+++K + LA +K V L + + L E + L
Sbjct: 1339 RQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIES-LEEAKKKL 1397
Query: 79 LNMVTALDTAMKRM----DAFNQEKVNQIQKTVIE---PLKKFGSVFPSLNMAVKRREQA 131
L AL ++ D + K N++Q+ + + L V +L K+ +Q
Sbjct: 1398 LKDAEALSQRLEEKALAYDKLEKTK-NRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQL 1456
Query: 132 LQDYRRLQAKVEKY------EEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPR 185
L + + + A+ + E +EK L+ L +A EE +E+FE +N+QL +M
Sbjct: 1457 LAEEKSISARYAEERDRAEAEAREKETKALS-LARALEEALEAKEEFERQNKQLRADMED 1515
Query: 186 FYGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLSHQLDQPGHSDEQRERENEAKLSEL 244
S+ D G H+L++ + EQ+ E +L EL
Sbjct: 1516 LMSSKDD-----------------------VGKNVHELEKSKRALEQQVEEMRTQLEEL 1551
Score = 37.0 bits (84), Expect = 0.016
Identities = 38/172 (22%), Positives = 81/172 (47%), Gaps = 18/172 (10%)
Query: 12 KKQIVPKTVERDFEREYGKLQQLEEQTRRLQKDMKKSTDADLAMSKSAVKISLDLLSNPL 71
K++++ +E ++E Q+LE+ R+L + DL + ++ +D L L
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGE-----TTDLQDQIAELQAQIDELKLQL 1085
Query: 72 CEQDQDLLN-MVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQ 130
+++++L + D + + +A + V ++Q + E + F S S N A K++
Sbjct: 1086 AKKEEELQGALARGDDETLHKNNAL--KVVRELQAQIAELQEDFESEKASRNKAEKQKRD 1143
Query: 131 ALQDYRRLQAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEE 182
++ L+ ++E + + T A++ELR RE A+ ++ LEE
Sbjct: 1144 LSEELEALKTELE--DTLDTTA--------AQQELRTKREQEVAELKKALEE 1185
Score = 32.7 bits (73), Expect = 0.31
Identities = 52/244 (21%), Positives = 102/244 (41%), Gaps = 30/244 (12%)
Query: 20 VERDFEREYGKLQQLEEQTRRLQKDMKK-STDADLAMSKSAVKISLDLLSNPLCEQDQDL 78
++ DFE E + E+Q R L ++++ T+ + + +A + L +++Q++
Sbjct: 1123 LQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQEL------RTKREQEV 1176
Query: 79 LNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQ-DYRR 137
+ AL+ K +A Q+ + Q T +E L + +++ +Q L+ D +
Sbjct: 1177 AELKKALEEETKNHEAQIQD-MRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKE 1235
Query: 138 L--------QAKVEKYEEKEKTGPVLAKLHQAREELRPVREDFEAKNRQLLEEMPRF--- 186
L Q K E +++K + +LH E +R + K +L E+
Sbjct: 1236 LACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTL 1295
Query: 187 ------YGSRLDYFQPSFESLIRAQVVYYSEMHKIFGDLS---HQLDQPGHS-DEQRERE 236
G + S ES ++ E + +LS QL++ +S EQ+E E
Sbjct: 1296 LEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEE 1355
Query: 237 NEAK 240
EA+
Sbjct: 1356 EEAR 1359
Score = 28.5 bits (62), Expect = 5.9
Identities = 31/164 (18%), Positives = 67/164 (40%), Gaps = 29/164 (17%)
Query: 20 VERDFEREYGKLQQLEEQTRR--LQKDMKKSTDADLAMSKSAVKISLDLLSNPLCEQDQD 77
+E + E E ++ L ++ R+ LQ D + +A+LA +SA + S
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVD---TLNAELAAERSAAQKS-------------- 1783
Query: 78 LLNMVTALDTAMKRMDAFNQEKVNQIQKTVIEPLKKFGSVFPSLNMAVKRREQALQDYRR 137
D A ++++ N+E ++Q+ KF + +L + + E+ L+ +
Sbjct: 1784 --------DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAK 1835
Query: 138 LQAKVEKY--EEKEKTGPVLAKLHQAREELRPVREDFEAKNRQL 179
+A K ++K + ++ R +E E N ++
Sbjct: 1836 ERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARM 1879
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,653,933
Number of Sequences: 37866
Number of extensions: 354436
Number of successful extensions: 2738
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 284
Number of HSP's that attempted gapping in prelim test: 2340
Number of HSP's gapped (non-prelim): 650
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.