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Search of human proteins with 8923771
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923771 ELG protein isoform b [Homo sapiens]
(340 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923771 ELG protein isoform b [Homo sapiens] 676 0.0
gi|166295179 ELG protein isoform a [Homo sapiens] 676 0.0
gi|210032580 SET domain containing 1B [Homo sapiens] 54 2e-07
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 54 3e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 52 6e-07
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 52 8e-07
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 52 1e-06
gi|17975763 myelin transcription factor 1 [Homo sapiens] 51 2e-06
gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s... 50 2e-06
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 49 5e-06
gi|33391150 nucleoplasmin 2 [Homo sapiens] 49 8e-06
gi|122937227 U2-associated SR140 protein [Homo sapiens] 48 1e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 48 1e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 48 1e-05
gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo sa... 47 2e-05
gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo sap... 47 2e-05
gi|13376339 plasticity-related protein 2 [Homo sapiens] 47 2e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 47 2e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 47 3e-05
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 47 3e-05
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 47 3e-05
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 47 3e-05
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 47 3e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 47 3e-05
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 47 3e-05
gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo s... 46 4e-05
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens] 46 5e-05
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens] 46 5e-05
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 46 5e-05
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 46 5e-05
>gi|8923771 ELG protein isoform b [Homo sapiens]
Length = 340
Score = 676 bits (1744), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 60
MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE
Sbjct: 1 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 60
Query: 61 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 120
EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD
Sbjct: 61 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 120
Query: 121 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 180
EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP
Sbjct: 121 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 180
Query: 181 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240
EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH
Sbjct: 181 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240
Query: 241 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 300
SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA
Sbjct: 241 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 300
Query: 301 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 340
WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES
Sbjct: 301 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 340
>gi|166295179 ELG protein isoform a [Homo sapiens]
Length = 620
Score = 676 bits (1744), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 1 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 60
MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE
Sbjct: 281 MKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPE 340
Query: 61 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 120
EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD
Sbjct: 341 EPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSD 400
Query: 121 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 180
EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP
Sbjct: 401 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 460
Query: 181 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240
EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH
Sbjct: 461 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 520
Query: 241 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 300
SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA
Sbjct: 521 SRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 580
Query: 301 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 340
WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES
Sbjct: 581 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 620
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/109 (33%), Positives = 54/109 (49%), Gaps = 14/109 (12%)
Query: 57 NVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERS--------- 107
++ EE EEEEE EEEEEEE+D D D+DDR E +E AL + E+
Sbjct: 1040 SLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEET 1099
Query: 108 ----ASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQ 152
S+ + SSS+S E + E S+PS + + + +E E +
Sbjct: 1100 VSIVTSKAEATSSSESSESS-EFESSSESSPSSSEDEEEVVAREEEEEE 1147
Score = 35.0 bits (79), Expect = 0.096
Identities = 40/172 (23%), Positives = 68/172 (39%), Gaps = 34/172 (19%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 123
E+EEE EEEEEEE+++M A++ + E+ + A+ A + DS M+
Sbjct: 1133 EDEEEVVAREEEEEEEEEEMVAEESMASAGPEDF----EQDGEEAALAPGAPAVDSLGME 1188
Query: 124 YDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKF 183
++++ E E+ R SM + ++ ++ PPE+
Sbjct: 1189 EEVDI-------------------ETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEE- 1228
Query: 184 ADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 235
L E P PP ++ + P SPE+A + V EP
Sbjct: 1229 ---PGLSQEGAMLLSPEPPAKEVEA-------RPPLSPERAPEHDLEVEPEP 1270
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 53.5 bits (127), Expect = 3e-07
Identities = 47/196 (23%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
Query: 34 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 93
KK+ G VG S L V ++ E EEE+E+E+ + + D+D D DD + +Y
Sbjct: 130 KKKKYRGKAVGPASI------LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY 183
Query: 94 HEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQL 153
+ + + ++ ++RRS + S S S+ S +S + + + S+
Sbjct: 184 NLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS 243
Query: 154 KNIRNSMRADSVSSSNIKNRIGNKLPPEK-FADVRHLLDEKRQHSRPRPPVSSTKSDIRQ 212
+ S S S S+ ++ G+ P ++ ++ + R+ SR R S+ S R+
Sbjct: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR----SSSSGDRK 299
Query: 213 RLGKRPHSPEKAFSSN 228
+ R SPE+ S+
Sbjct: 300 KRRTRSRSPERRHRSS 315
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 52.4 bits (124), Expect = 6e-07
Identities = 27/72 (37%), Positives = 39/72 (54%)
Query: 56 VNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSAS 115
+N +E EEEEEEEEEEEEEEEE++D + ++ EY EE ++ E
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942
Query: 116 SSDSDEMDYDLE 127
+ +E D + E
Sbjct: 943 EEEEEEEDEEEE 954
Score = 45.1 bits (105), Expect = 9e-05
Identities = 23/68 (33%), Positives = 36/68 (52%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 119
EE EEEEEEEEEEEEEE+ +++ + ++ E EE ++ E +
Sbjct: 891 EEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEED 950
Query: 120 DEMDYDLE 127
+E + +LE
Sbjct: 951 EEEEEELE 958
Score = 42.0 bits (97), Expect = 8e-04
Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 119
EE EEEEEEE+ EEEEE+E++ + ++ E+ EE + E +
Sbjct: 898 EEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957
Query: 120 DEMDYDLE 127
+E++ DLE
Sbjct: 958 EEVE-DLE 964
Score = 35.8 bits (81), Expect = 0.056
Identities = 16/34 (47%), Positives = 25/34 (73%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 93
EE EEEE E EEEEEEE+E+++ + ++ +E+
Sbjct: 932 EEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEF 965
Score = 29.3 bits (64), Expect = 5.3
Identities = 13/24 (54%), Positives = 16/24 (66%)
Query: 59 PEEPIEEEEEEEEEEEEEEEEDQD 82
PE P EEE E E E E +E++QD
Sbjct: 1080 PETPAEEEMETETEAEALQEKEQD 1103
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 52.0 bits (123), Expect = 8e-07
Identities = 46/190 (24%), Positives = 85/190 (44%), Gaps = 11/190 (5%)
Query: 34 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEY 93
KK+ G VG S L V ++ E EEE+E+E+ + + D+D D DD + +Y
Sbjct: 130 KKKKYRGKAVGPASI------LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY 183
Query: 94 HEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQL 153
+ + + ++ ++RRS + S S S+ S +S + + + S+
Sbjct: 184 NLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRS 243
Query: 154 KNIRNSMRADSVSSSNIKNRIGNKLPPEK-FADVRHLLDEKRQHSRPRPPVSSTKSDIRQ 212
+ S S S S+ ++ G+ P ++ ++ + R+ SR R S+ S R+
Sbjct: 244 SSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSR----SSSSGDRK 299
Query: 213 RLGKRPHSPE 222
+ R SPE
Sbjct: 300 KRRTRSRSPE 309
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 51.6 bits (122), Expect = 1e-06
Identities = 61/239 (25%), Positives = 95/239 (39%), Gaps = 38/239 (15%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVV----EYHEELPALK-------QPRERSA 108
EE EEEEEEEE++EEEE +D+ + + ++ E EE+P +K +P+ RS
Sbjct: 270 EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQ 329
Query: 109 SRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 168
+ + ++ +K MK T +E E ++K SS
Sbjct: 330 EQEVLERGGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIK-----------SSQ 378
Query: 169 NIKNRIGNKLPPEKFADVRH----LLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKA 224
+K + + PP D + L E+ PP TK + HS E+
Sbjct: 379 GLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEEEI 438
Query: 225 FSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRL--GSAPKTKEKNTK 281
P+ P+ V +L P D ADTRE +L G +P + +TK
Sbjct: 439 ---EPM--EGPAPPVLIQLSPPNTD-----ADTRELLVSQHTVQLVGGLSPLSSPSDTK 487
Score = 30.0 bits (66), Expect = 3.1
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 6/85 (7%)
Query: 58 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRE----RSASRRSS 113
VP E E + EEEEEE+E E + + +V VE PA + ++ + +RRS
Sbjct: 925 VPAEGQENGQREEEEEEKEPEAEPPV--PPQVSVEVALPPPAEHEVKKVTLGDTLTRRSI 982
Query: 114 ASSSDSDEMDYDLELKMISTPSPKK 138
+ + D ++ PSP +
Sbjct: 983 SQQKSGVSITIDDPVRTAQVPSPPR 1007
Score = 29.6 bits (65), Expect = 4.0
Identities = 16/63 (25%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 61 EPIEEEEEEEEEEEEEEEEDQDMDAD---DRVVVEYHEELPALKQPRERSASRRSSASSS 117
E +E E+ +E+EEEE+++++ +A+ +R + + ++ RER R
Sbjct: 1243 ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDR 1302
Query: 118 DSD 120
D D
Sbjct: 1303 DRD 1305
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/126 (26%), Positives = 63/126 (50%), Gaps = 3/126 (2%)
Query: 51 RHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASR 110
+ G+++ EE EEEEEEEEEEE+EEEE+++ + ++ E EE ++ E A+
Sbjct: 250 KQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
Query: 111 R---SSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSS 167
+S S + +L +P P+ S+ + + +D+ + + + R S D
Sbjct: 310 DVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEM 369
Query: 168 SNIKNR 173
++ R
Sbjct: 370 QDMMTR 375
>gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo
sapiens]
Length = 652
Score = 50.4 bits (119), Expect = 2e-06
Identities = 59/246 (23%), Positives = 95/246 (38%), Gaps = 37/246 (15%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSDEM 122
+ E + E EEEE+E+ED+D D D+R ++ E+ +EL + P +R R + D D +
Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465
Query: 123 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEK 182
+ E + M + +K + + V K + K PP
Sbjct: 466 KKESE----------RDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPPS- 514
Query: 183 FADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGK-RPHSPEKAFSSNPVVRREPSSDVHS 241
P+P + +R R+ K R P + + + R P
Sbjct: 515 ----------------PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENPQLKQIE 558
Query: 242 RLGVPRQDSKGLYADTR-EKKSGNLW---TRLGSAPKTKE--KNTKKV--DHRAPGAEED 293
L + +GL A + E K W T G+ T E +N K++ + PGAEE
Sbjct: 559 GLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILVPGAEEA 618
Query: 294 DSELQR 299
E QR
Sbjct: 619 QKERQR 624
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 49.3 bits (116), Expect = 5e-06
Identities = 39/126 (30%), Positives = 60/126 (47%), Gaps = 12/126 (9%)
Query: 58 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSA--------S 109
V E+ EEEEEEEEEEEEEEEE+++ + D+R E + + + + S
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284
Query: 110 RRSSASSSDSDEMDYDLELKMISTP---SPKKSMKMTMYADEVESQLKNIRNSMRADSVS 166
RS + + SDE + + +P S YAD+ S+LK + R +
Sbjct: 285 VRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYADQT-SKLKYVLQDARFFLIK 343
Query: 167 SSNIKN 172
S+N +N
Sbjct: 344 SNNHEN 349
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 119
EE +EE+ EE+EE EE+ EED+++D D E EE ++ E D
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE----EEEEEEEEEEEYEQDERDQ 257
Query: 120 DEMDYDLELKMISTPSPKKSMKMT 143
E D + + ++ S +S+ T
Sbjct: 258 KEEGNDYDTRSEASDSGSESVSFT 281
Score = 42.0 bits (97), Expect = 8e-04
Identities = 28/98 (28%), Positives = 48/98 (48%), Gaps = 8/98 (8%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 119
EE EE+EE +E+ EEEEEE+++ + ++ E +E+ ++ RS AS S S
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 120 DEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIR 157
+ + + T +S T +DE + + K R
Sbjct: 276 ESVSF--------TDGSVRSGSGTDGSDEKKKERKRAR 305
>gi|33391150 nucleoplasmin 2 [Homo sapiens]
Length = 214
Score = 48.5 bits (114), Expect = 8e-06
Identities = 31/83 (37%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 123
EEEEEE EEEEEEEE+D+D DAD + EE +KQ + +++S + E +
Sbjct: 130 EEEEEEGEEEEEEEEDDEDEDADISL-----EEQSPVKQVKRLVPQKQASVAKKKKLEKE 184
Query: 124 YDLELKMISTPSPKKSMKMTMYA 146
+ + SP K K T A
Sbjct: 185 EEEIRASVRDKSPVKKAKATARA 207
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 48.1 bits (113), Expect = 1e-05
Identities = 55/239 (23%), Positives = 97/239 (40%), Gaps = 19/239 (7%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 123
EE EEEE + +EEE ED++ D E+H +K+ S + S S +
Sbjct: 786 EESEEEENQNQEEESEDEE-DTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKL 844
Query: 124 YDLELKMI-------STPSPKK-----SMKMTMYADEV--ESQLKNIRNSMRADSVSSSN 169
++ELK++ S PKK ++ Y D++ + K + D
Sbjct: 845 REIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEK 904
Query: 170 IKNRIGNKLPPEKFADVRHLLDEKRQHS-RPRPPVSSTKSDIRQRLGKRPHSPEKAFSSN 228
+++R +K ++ R + KR+HS P P SS+ ++ K S E++ S+
Sbjct: 905 LESRSKDKKEKDECTPTRK--ERKRRHSTSPSPSRSSSGRRVKSPSPKSERS-ERSERSH 961
Query: 229 PVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRA 287
R SS S V ++ + K+S +R K ++ + HR+
Sbjct: 962 KESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRS 1020
Score = 32.0 bits (71), Expect = 0.82
Identities = 52/263 (19%), Positives = 84/263 (31%), Gaps = 57/263 (21%)
Query: 61 EPIEEEEEEEEEEEEEEEED----------------------------QDMDADDRV--- 89
E EEEE + +EEE E+EED +M + R
Sbjct: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845
Query: 90 -----VVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTM 144
V+++ +EL + K+P++ S + + + E ++ K K
Sbjct: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDK--- 902
Query: 145 YADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVS 204
+++ES+ K+ + K R P + + R + + R
Sbjct: 903 --EKLESRSKDKKEKDECTPTRKER-KRRHSTSPSPSRSSSGRRVKSPSPKSERSERSER 959
Query: 205 STKSDIRQRLGKR--PHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKS 262
S K R R + P K +P R P SR P KKS
Sbjct: 960 SHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSP-------------KKS 1006
Query: 263 GNLWTRLGSAPKTKEKNTKKVDH 285
G +P K +KK H
Sbjct: 1007 GKKSRSQSRSPHRSHKKSKKNKH 1029
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 47.8 bits (112), Expect = 1e-05
Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS------- 112
E+ ++E+E+E+++E+E E+D+ + D++ + P PR +ASRRS
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRER 497
Query: 113 ----SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 168
S SSS S ++ K +PSP+ K ++ + R R+ S+ S
Sbjct: 498 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557
Query: 169 NIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSD 209
+ +R G EK L EK + P VS D
Sbjct: 558 S-NDRDGK----EKLEKNSTSLKEKEHNKEPDSSVSKEVDD 593
Score = 38.9 bits (89), Expect = 0.007
Identities = 55/244 (22%), Positives = 87/244 (35%), Gaps = 37/244 (15%)
Query: 58 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 117
V E+ E+E E E+E E+E+E ++ D D ++ RE+ +
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKE-----------REKDREKDKEKDRERERE 438
Query: 118 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVS--SSNIKNRIG 175
E D D E + ++ + DE + K R R+ + S S +
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 498
Query: 176 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 235
+ R KR+ SR P S K D ++R +R H E+ R+
Sbjct: 499 RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-KKREKERDHISERRERERSTSMRKS 557
Query: 236 SSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDS 295
S+D +D K + EK S +L KEK K + E DD
Sbjct: 558 SND---------RDGK----EKLEKNSTSL----------KEKEHNKEPDSSVSKEVDDK 594
Query: 296 ELQR 299
+ R
Sbjct: 595 DAPR 598
Score = 35.8 bits (81), Expect = 0.056
Identities = 45/195 (23%), Positives = 73/195 (37%), Gaps = 15/195 (7%)
Query: 146 ADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSS 205
A E+E +K +R A S S+ I+ G + H + R S+
Sbjct: 272 AKELEEVMKRVRE---AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKR 328
Query: 206 TKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNL 265
++S R R R S +K + ++ S R R S+ DTREK
Sbjct: 329 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK----- 383
Query: 266 WTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGA-LIKEKEQSRQKKSRLDNLPSL 324
+ + KEK+ +K R +E + E +R KE+E+ R+K D
Sbjct: 384 ---IKEKERVKEKDREKERER---EKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 437
Query: 325 QIEVSRESSSGSEAE 339
+ E ++ E E
Sbjct: 438 EKEHEKDRDKEKEKE 452
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 47.8 bits (112), Expect = 1e-05
Identities = 42/161 (26%), Positives = 70/161 (43%), Gaps = 20/161 (12%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS------- 112
E+ ++E+E+E+++E+E E+D+ + D++ + P PR +ASRRS
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRER 381
Query: 113 ----SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSS 168
S SSS S ++ K +PSP+ K ++ + R R+ S+ S
Sbjct: 382 RRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441
Query: 169 NIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSD 209
+ +R G EK L EK + P VS D
Sbjct: 442 S-NDRDGK----EKLEKNSTSLKEKEHNKEPDSSVSKEVDD 477
Score = 38.9 bits (89), Expect = 0.007
Identities = 55/244 (22%), Positives = 87/244 (35%), Gaps = 37/244 (15%)
Query: 58 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 117
V E+ E+E E E+E E+E+E ++ D D ++ RE+ +
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKE-----------REKDREKDKEKDRERERE 322
Query: 118 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVS--SSNIKNRIG 175
E D D E + ++ + DE + K R R+ + S S +
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 382
Query: 176 NKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREP 235
+ R KR+ SR P S K D ++R +R H E+ R+
Sbjct: 383 RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD-KKREKERDHISERRERERSTSMRKS 441
Query: 236 SSDVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDS 295
S+D +D K + EK S +L KEK K + E DD
Sbjct: 442 SND---------RDGK----EKLEKNSTSL----------KEKEHNKEPDSSVSKEVDDK 478
Query: 296 ELQR 299
+ R
Sbjct: 479 DAPR 482
Score = 35.8 bits (81), Expect = 0.056
Identities = 45/195 (23%), Positives = 73/195 (37%), Gaps = 15/195 (7%)
Query: 146 ADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSS 205
A E+E +K +R A S S+ I+ G + H + R S+
Sbjct: 156 AKELEEVMKRVRE---AQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKR 212
Query: 206 TKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGNL 265
++S R R R S +K + ++ S R R S+ DTREK
Sbjct: 213 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK----- 267
Query: 266 WTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGA-LIKEKEQSRQKKSRLDNLPSL 324
+ + KEK+ +K R +E + E +R KE+E+ R+K D
Sbjct: 268 ---IKEKERVKEKDREKERER---EKEREKEKERGKNKDRDKEREKDREKDKEKDRERER 321
Query: 325 QIEVSRESSSGSEAE 339
+ E ++ E E
Sbjct: 322 EKEHEKDRDKEKEKE 336
>gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo
sapiens]
Length = 667
Score = 47.0 bits (110), Expect = 2e-05
Identities = 59/252 (23%), Positives = 100/252 (39%), Gaps = 34/252 (13%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSD-- 120
+ E + E EEEE+E+ED+D D D+R ++ E+ +EL + P +R R + + +
Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGMERELE 465
Query: 121 ----EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGN 176
E + +L+ + S ++ M + +K + + V K +
Sbjct: 466 NIIQETEKELDPDGLKKES-ERDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPK 524
Query: 177 KLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGK-RPHSPEKAFSSNPVVRREP 235
K PP P+P + +R R+ K R P + + + R P
Sbjct: 525 KPPPS-----------------PQPTEEDPEHRVRVRVTKLRLGGPNQDLTVLEMKRENP 567
Query: 236 SSDVHSRLGVPRQDSKGLYADTR-EKKSGNLW---TRLGSAPKTKE--KNTKKV--DHRA 287
L + +GL A + E K W T G+ T E +N K++ +
Sbjct: 568 QLKQIEGLVKELLEREGLTAAGKIEIKIVRPWAEGTEEGARWLTDEDTRNLKEIFFNILV 627
Query: 288 PGAEEDDSELQR 299
PGAEE E QR
Sbjct: 628 PGAEEAQKERQR 639
>gi|48255889 protein kinase C substrate 80K-H isoform 1 [Homo
sapiens]
Length = 528
Score = 47.0 bits (110), Expect = 2e-05
Identities = 38/118 (32%), Positives = 55/118 (46%), Gaps = 23/118 (19%)
Query: 45 LTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPR 104
LT K + + P E EEEEEEEEEE EEEEE++D + E P L P+
Sbjct: 297 LTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSE----------EAPPPLSPPQ 346
Query: 105 ERSASRRSSASSSDSDEM-DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMR 161
AS ++ D+M YD + + + + K +E E LK++ S+R
Sbjct: 347 --------PASPAEEDKMPPYDEQTQAFIDAAQEARNKF----EEAERSLKDMEESIR 392
>gi|13376339 plasticity-related protein 2 [Homo sapiens]
Length = 746
Score = 47.0 bits (110), Expect = 2e-05
Identities = 24/51 (47%), Positives = 34/51 (66%), Gaps = 2/51 (3%)
Query: 34 KKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMD 84
K+++L G +GL G + P EP+ EEEEEEE+EEEEEEE+++ D
Sbjct: 440 KQKSLEGRGLGLPD--DASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEED 488
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 47.0 bits (110), Expect = 2e-05
Identities = 41/129 (31%), Positives = 62/129 (48%), Gaps = 21/129 (16%)
Query: 58 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 117
V E+ EEEEEEEEEEEEEEEE+++ + D+R + EE RS AS S
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDER---DQKEE--------GNDYDTRSEASDS 273
Query: 118 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIR--NSMRADSVSSSNIKNRIG 175
S+ + + T +S T +DE + + K R + + D SS ++ G
Sbjct: 274 GSESVSF--------TDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAG 325
Query: 176 NKLPPEKFA 184
++ EK +
Sbjct: 326 SEKKHEKLS 334
Score = 43.1 bits (100), Expect = 4e-04
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 119
EE +EE+ EE+EE EE+ EED+++D D E EE ++ E D
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE----EEEEEEEEEEEYEQDERDQ 257
Query: 120 DEMDYDLELKMISTPSPKKSMKMT 143
E D + + ++ S +S+ T
Sbjct: 258 KEEGNDYDTRSEASDSGSESVSFT 281
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 46.6 bits (109), Expect = 3e-05
Identities = 55/199 (27%), Positives = 83/199 (41%), Gaps = 14/199 (7%)
Query: 8 YGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEE 67
Y K LS+ +R R++R L V L + + +G EE +EEE
Sbjct: 685 YQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEE 744
Query: 68 EEE----EEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMD 123
EEE EEEEEEEEE+++ + ++ L + PR S+S S S+ S E
Sbjct: 745 EEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEG- 803
Query: 124 YDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNI-KNRIGNKLPPEK 182
+ K+S AD L+ S VS ++ K+ + +L P+
Sbjct: 804 ---APSTLLADDQKESRGRASMAD---GDLEPEEGSKTLVLVSPGDMKKSPVTAELAPD- 856
Query: 183 FADVRHLLDEKRQHSRPRP 201
D+ L QH RP+P
Sbjct: 857 -PDLGTLAALTPQHERPQP 874
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 46.6 bits (109), Expect = 3e-05
Identities = 64/290 (22%), Positives = 123/290 (42%), Gaps = 41/290 (14%)
Query: 49 KHRHSGLVN--------VPEEPIEEEEEEE-----EEEEEEEEEDQDMDADDRVVVEYHE 95
KH +S +V V +EP E+ + E E E +EE+++ D ++ EY
Sbjct: 1027 KHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFR 1086
Query: 96 ELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMKMTMYADEVESQL 153
L + R +S+S+R S + +E D + ++ S K+ +K + + + L
Sbjct: 1087 RLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPL 1146
Query: 154 KNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQR 213
K + + S + K R G K P K + R ++ Q P VS K+
Sbjct: 1147 KKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEPIVSIPKA----- 1198
Query: 214 LGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGN----LWTRL 269
G++P E S V EP D+ L R++ + + A+ E + G + +
Sbjct: 1199 -GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAEEGEEEDAASSEV 1249
Query: 270 GSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLD 319
+A N+ + + + P EE++ + + + +E+ QS +++ L+
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQELE 1294
Score = 39.7 bits (91), Expect = 0.004
Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%)
Query: 58 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 117
+PEE EEEE + E EE EE E++D + E+PA S A SS
Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258
Query: 118 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 177
+S E + T P+ E E + + R ++
Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296
Query: 178 LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 237
PE+ D + H +S ++ L ++P + V+ EP
Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345
Query: 238 DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 297
GV +REK T L S + +T V + G+E+D E
Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 298 QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 339
LI+ KE+ S LD L ++Q S SE E
Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440
Score = 29.3 bits (64), Expect = 5.3
Identities = 56/258 (21%), Positives = 93/258 (36%), Gaps = 47/258 (18%)
Query: 63 IEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEM 122
+ EEEEEE EE E EE Q Q RE S S S + ++
Sbjct: 785 VVSEEEEEEAEEGENEEPQ-------------------CQERELEISVGKSVSHENKEQD 825
Query: 123 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEK 182
Y +E S KK M + S+ +S+ A+S S + N+ E+
Sbjct: 826 SYSVE-------SEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQER 878
Query: 183 FA--DVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240
F D + LL+E SS + G++ + ++ ++ E +
Sbjct: 879 FGDKDSKLLLEE----------TSSAPQEQYGECGEKSEATQEQYT-------ESEEQLV 921
Query: 241 SRLGVPRQDSKGLYADTREKKSGNLWT-RLGSAPKTKEKNTKKVDHRAPGA-EEDDSELQ 298
+ P QD K R + W +L +P+ + + R P E D +
Sbjct: 922 ASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVL 981
Query: 299 RAWGALIKEKEQSRQKKS 316
R + +E+E+ +S
Sbjct: 982 RGFSESSEEEEEPESPRS 999
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 46.6 bits (109), Expect = 3e-05
Identities = 64/290 (22%), Positives = 123/290 (42%), Gaps = 41/290 (14%)
Query: 49 KHRHSGLVN--------VPEEPIEEEEEEE-----EEEEEEEEEDQDMDADDRVVVEYHE 95
KH +S +V V +EP E+ + E E E +EE+++ D ++ EY
Sbjct: 1027 KHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFR 1086
Query: 96 ELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMKMTMYADEVESQL 153
L + R +S+S+R S + +E D + ++ S K+ +K + + + L
Sbjct: 1087 RLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPL 1146
Query: 154 KNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQR 213
K + + S + K R G K P K + R ++ Q P VS K+
Sbjct: 1147 KKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEPIVSIPKA----- 1198
Query: 214 LGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGN----LWTRL 269
G++P E S V EP D+ L R++ + + A+ E + G + +
Sbjct: 1199 -GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAEEGEEEDAASSEV 1249
Query: 270 GSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLD 319
+A N+ + + + P EE++ + + + +E+ QS +++ L+
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQELE 1294
Score = 39.7 bits (91), Expect = 0.004
Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%)
Query: 58 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 117
+PEE EEEE + E EE EE E++D + E+PA S A SS
Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258
Query: 118 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 177
+S E + T P+ E E + + R ++
Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296
Query: 178 LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 237
PE+ D + H +S ++ L ++P + V+ EP
Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345
Query: 238 DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 297
GV +REK T L S + +T V + G+E+D E
Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 298 QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 339
LI+ KE+ S LD L ++Q S SE E
Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440
Score = 29.3 bits (64), Expect = 5.3
Identities = 56/258 (21%), Positives = 93/258 (36%), Gaps = 47/258 (18%)
Query: 63 IEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEM 122
+ EEEEEE EE E EE Q Q RE S S S + ++
Sbjct: 785 VVSEEEEEEAEEGENEEPQ-------------------CQERELEISVGKSVSHENKEQD 825
Query: 123 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEK 182
Y +E S KK M + S+ +S+ A+S S + N+ E+
Sbjct: 826 SYSVE-------SEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQER 878
Query: 183 FA--DVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240
F D + LL+E SS + G++ + ++ ++ E +
Sbjct: 879 FGDKDSKLLLEE----------TSSAPQEQYGECGEKSEATQEQYT-------ESEEQLV 921
Query: 241 SRLGVPRQDSKGLYADTREKKSGNLWT-RLGSAPKTKEKNTKKVDHRAPGA-EEDDSELQ 298
+ P QD K R + W +L +P+ + + R P E D +
Sbjct: 922 ASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVL 981
Query: 299 RAWGALIKEKEQSRQKKS 316
R + +E+E+ +S
Sbjct: 982 RGFSESSEEEEEPESPRS 999
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 46.6 bits (109), Expect = 3e-05
Identities = 64/290 (22%), Positives = 123/290 (42%), Gaps = 41/290 (14%)
Query: 49 KHRHSGLVN--------VPEEPIEEEEEEE-----EEEEEEEEEDQDMDADDRVVVEYHE 95
KH +S +V V +EP E+ + E E E +EE+++ D ++ EY
Sbjct: 1027 KHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEPTFEIDEEEEEEDENELFPREYFR 1086
Query: 96 ELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPS--PKKSMKMTMYADEVESQL 153
L + R +S+S+R S + +E D + ++ S K+ +K + + + L
Sbjct: 1087 RLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSLLRKRDVKNSPLEPDTSTPL 1146
Query: 154 KNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQR 213
K + + S + K R G K P K + R ++ Q P VS K+
Sbjct: 1147 KKKKGWPKGKSRKPIHWKKRPGRK-PGFKLS--REIMPVSTQACVIEPIVSIPKA----- 1198
Query: 214 LGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREKKSGN----LWTRL 269
G++P E S V EP D+ L R++ + + A+ E + G + +
Sbjct: 1199 -GRKPKIQE---SEETV---EPKEDM--PLPEERKEEEEMQAEAEEAEEGEEEDAASSEV 1249
Query: 270 GSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLD 319
+A N+ + + + P EE++ + + + +E+ QS +++ L+
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPR-----VSEEQRQSEEEQQELE 1294
Score = 39.7 bits (91), Expect = 0.004
Identities = 65/282 (23%), Positives = 97/282 (34%), Gaps = 60/282 (21%)
Query: 58 VPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSS 117
+PEE EEEE + E EE EE E++D + E+PA S A SS
Sbjct: 1219 LPEERKEEEEMQAEAEEAEEGEEEDAASS---------EVPAA-----------SPADSS 1258
Query: 118 DSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNK 177
+S E + T P+ E E + + R ++
Sbjct: 1259 NSPETE---------TKEPEV---------EEEEEKPRVSEEQRQSEEEQQELEEP---- 1296
Query: 178 LPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSS 237
PE+ D + H +S ++ L ++P + V+ EP
Sbjct: 1297 -EPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTRED--------VKEEP-- 1345
Query: 238 DVHSRLGVPRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSEL 297
GV +REK T L S + +T V + G+E+D E
Sbjct: 1346 ------GVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQMAGSEDDHEED 1399
Query: 298 QRAWGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAE 339
LI+ KE+ S LD L ++Q S SE E
Sbjct: 1400 SHTKEELIELKEEEEIPHSELD-LETVQAVQSLTQEESSEHE 1440
Score = 29.3 bits (64), Expect = 5.3
Identities = 56/258 (21%), Positives = 93/258 (36%), Gaps = 47/258 (18%)
Query: 63 IEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEM 122
+ EEEEEE EE E EE Q Q RE S S S + ++
Sbjct: 785 VVSEEEEEEAEEGENEEPQ-------------------CQERELEISVGKSVSHENKEQD 825
Query: 123 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEK 182
Y +E S KK M + S+ +S+ A+S S + N+ E+
Sbjct: 826 SYSVE-------SEKKPEVMAPVSSTRLSKQVLPHDSLPANSQPSRRGRWGRKNRKTQER 878
Query: 183 FA--DVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240
F D + LL+E SS + G++ + ++ ++ E +
Sbjct: 879 FGDKDSKLLLEE----------TSSAPQEQYGECGEKSEATQEQYT-------ESEEQLV 921
Query: 241 SRLGVPRQDSKGLYADTREKKSGNLWT-RLGSAPKTKEKNTKKVDHRAPGA-EEDDSELQ 298
+ P QD K R + W +L +P+ + + R P E D +
Sbjct: 922 ASEEQPSQDGKPDLPKRRLSEGVEPWRGQLKKSPEALKCRLTEGSERLPRRYSEGDRAVL 981
Query: 299 RAWGALIKEKEQSRQKKS 316
R + +E+E+ +S
Sbjct: 982 RGFSESSEEEEEPESPRS 999
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
Query: 55 LVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSA 114
L ++ ++ EEEEEE EEEEEE EE+++ D ++ E EE ++P++R +S+
Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEE----EEPQQRGQGEKSAT 409
Query: 115 SSSDSDEMDYDLELKMISTPSP 136
S + + ++S+P P
Sbjct: 410 PSRKILDPNTGEPAPVLSSPPP 431
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 46.6 bits (109), Expect = 3e-05
Identities = 24/70 (34%), Positives = 37/70 (52%)
Query: 56 VNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSAS 115
+ V E P EEEEEEEEEEE+EE E+++ + + E EE + ++ + S
Sbjct: 525 IEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS 584
Query: 116 SSDSDEMDYD 125
S + +YD
Sbjct: 585 KEMSSDSEYD 594
Score = 41.6 bits (96), Expect = 0.001
Identities = 24/62 (38%), Positives = 34/62 (54%)
Query: 60 EEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDS 119
EE EEEE+EE EEEEEEE + + D + +E + K ++ + SS S DS
Sbjct: 536 EEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDS 595
Query: 120 DE 121
D+
Sbjct: 596 DD 597
Score = 40.8 bits (94), Expect = 0.002
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 59 PEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSD 118
PEE EEEEEEEEE+EE EEE+++ + + +E + ++ ++ ++ S S
Sbjct: 531 PEEE-EEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS 589
Query: 119 SDEMDYD 125
E D D
Sbjct: 590 DSEYDSD 596
Score = 38.9 bits (89), Expect = 0.007
Identities = 63/340 (18%), Positives = 137/340 (40%), Gaps = 31/340 (9%)
Query: 20 KRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEE-----EE 74
K++ R+ + + +K + + D G+ + E+ E +++++++ E+
Sbjct: 268 KQKESQRKFEEETVKSKVTV--DTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEK 325
Query: 75 EEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDL--ELKMIS 132
EE+E+++ V E L LK+ ER R +E++ E ++
Sbjct: 326 EEKEKEKKKGPSKATVKAMQEALAKLKEEEERQ-KREEEERIKRLEELEAKRKEEERLEQ 384
Query: 133 TPSPKKSMKMTMYADEVESQLKNIRNSM---RADSVSSSNIKNRIGNKLP-PEKFADVRH 188
+K K + ++ + K + S RA + ++ + G ++P + R
Sbjct: 385 EKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRP 444
Query: 189 LLDEKRQHSRPRPPVSSTKSDIRQRLG----KRPHSPEKAFSSNPVVRREPSSDVHSRLG 244
+ ++K++ P+ S S+ + PEK + PV E + L
Sbjct: 445 IYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGL- 503
Query: 245 VPRQDSKGLYADTR-EKKSGN---LWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRA 300
D + + +D EK GN + + + +E+ ++ D + EE++ E + +
Sbjct: 504 ---DDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGS 560
Query: 301 WGALIKEKEQSRQKKSRLDNLPSLQIEVSRESSSGSEAES 340
G E+ + D+ +L + S+E SS SE +S
Sbjct: 561 EG-----DEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDS 595
Score = 32.3 bits (72), Expect = 0.62
Identities = 70/348 (20%), Positives = 119/348 (34%), Gaps = 82/348 (23%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADD--RVVVEYHEELPALKQPRERSA------------- 108
E+E ++ + ++++E++ QD D DD + + E E +K RE A
Sbjct: 34 EQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTS 93
Query: 109 ---------SRRSSASSSDSDEMDYDLELKMISTPSPK---------------------- 137
++ S +DS+E++ D + K T PK
Sbjct: 94 KDKKKKGQKGKKQSFDDNDSEELE-DKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKG 152
Query: 138 ---KSMKMTMYADEVESQLKNIRNSMRADSVSSS----------------NIKNRIGNKL 178
KS K ++E E K I+ R +S S N KN+ G +
Sbjct: 153 KAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212
Query: 179 PPE--------KFADVRHLLDEKRQHSR-----PRPPVSSTKSDIRQRLGKRPHSPEKAF 225
K V EK++ R + + K GK+ S +K
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKE- 271
Query: 226 SSNPVVRREPSSDVHSRLGV-PRQDSKGLYADTREKKSGNLWTRLGSAPKTKEKNTKKVD 284
S S V GV P + K E + + K EK K+ +
Sbjct: 272 SQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKE 331
Query: 285 HRAPGAEEDDSELQRAWGALIKEKE-QSRQKKSRLDNLPSLQIEVSRE 331
+ ++ +Q A L +E+E Q R+++ R+ L L+ + E
Sbjct: 332 KKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEE 379
Score = 29.3 bits (64), Expect = 5.3
Identities = 29/125 (23%), Positives = 50/125 (40%), Gaps = 12/125 (9%)
Query: 56 VNVPEEPIEEEEEEEEEEEEEEEED-QDMDADDRVVVEYHEE----------LPALKQPR 104
V V E+ + E+EE E EEEED +D DD + EE + + P
Sbjct: 473 VEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPE 532
Query: 105 ERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADS 164
E +S+E + + E + + ++ K++ D ++ K M +DS
Sbjct: 533 EEEEEEEEEEEDEESEEEEEE-EGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDS 591
Query: 165 VSSSN 169
S+
Sbjct: 592 EYDSD 596
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 46.6 bits (109), Expect = 3e-05
Identities = 26/79 (32%), Positives = 42/79 (53%)
Query: 49 KHRHSGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSA 108
KH+ S EE EEEE ++++++++EED D +D ++ Q ++R+
Sbjct: 213 KHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIESKVTKPVQIQKRAV 272
Query: 109 SRRSSASSSDSDEMDYDLE 127
R + A SSD E D DLE
Sbjct: 273 KRPAPAKSSDHSEEDSDLE 291
Score = 35.0 bits (79), Expect = 0.096
Identities = 34/156 (21%), Positives = 77/156 (49%), Gaps = 21/156 (13%)
Query: 60 EEPIEEEEEEEEEEEEEEE---------EDQDMDADDRVVVEYHEELPALKQPRERSASR 110
EE +EEEE ++++++++EE E++++++ +V + A+K+P +S
Sbjct: 225 EEDMEEEENDDDDDDDDEEDGVFDDEDEEEENIES--KVTKPVQIQKRAVKRPAPAKSSD 282
Query: 111 RSSASS--SDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRA---DSV 165
S S +SD +D EL T + ++ K +++ + +L + N + ++
Sbjct: 283 HSEEDSDLEESDSIDDGEELAQSDTSTEEQEDKAVQVSNKKKRKLPSDVNEGKTVFIRNL 342
Query: 166 SSSNIKNRIGNKLPPEKFAD---VRHLLDEKRQHSR 198
S + + +G L ++F + VR +L +HS+
Sbjct: 343 SFDSEEEELGELL--QQFGELKYVRIVLHPDTEHSK 376
>gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo
sapiens]
Length = 597
Score = 46.2 bits (108), Expect = 4e-05
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 11/118 (9%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVV-EYHEELPALKQPRERSASRRSSASSSDSDEM 122
+ E + E EEEE+E+ED+D D D+R ++ E+ +EL + P +R R + D D +
Sbjct: 406 DPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKELDPDGL 465
Query: 123 DYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 180
+ E + M + +K + + V K + K PP
Sbjct: 466 KKESE----------RDRAMLALTSTLNKLIKRLEEKQSPELVKKHKKKRVVPKKPPP 513
>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
Length = 259
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 15/130 (11%)
Query: 41 DDVGLTSYKHRHS---GLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEEL 97
+DV L S + S G VP++ ++ +E++++++EE++D+D D DD E E+
Sbjct: 131 EDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKA 190
Query: 98 PALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPK-----KSMKMTMYADEVESQ 152
P K R+ A ++ + D K STP K K + T + S
Sbjct: 191 PVKKSIRDTPAKNAQKSNQNGKDS-------KPSSTPRSKGQESFKKQEKTPKTPKGPSS 243
Query: 153 LKNIRNSMRA 162
+++I+ M+A
Sbjct: 244 VEDIKAKMQA 253
Score = 28.5 bits (62), Expect = 9.0
Identities = 31/163 (19%), Positives = 60/163 (36%), Gaps = 18/163 (11%)
Query: 53 SGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS 112
SG V++ + + EE+ E E+EEEE+ + + + K+ + +
Sbjct: 106 SGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDD 165
Query: 113 SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKN 172
D DE D D + + DE + ++ S+R ++ N
Sbjct: 166 DDDEEDDDEDDDDDD-----------------FDDEEAEEKAPVKKSIRDTPAKNAQKSN 208
Query: 173 RIGNKLPPEKFADVRHLLDEKRQHSRPRPPVS-STKSDIRQRL 214
+ G P + K+Q P+ P S+ DI+ ++
Sbjct: 209 QNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKM 251
>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
Length = 294
Score = 45.8 bits (107), Expect = 5e-05
Identities = 34/130 (26%), Positives = 62/130 (47%), Gaps = 15/130 (11%)
Query: 41 DDVGLTSYKHRHS---GLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEEL 97
+DV L S + S G VP++ ++ +E++++++EE++D+D D DD E E+
Sbjct: 131 EDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKA 190
Query: 98 PALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPK-----KSMKMTMYADEVESQ 152
P K R+ A ++ + D K STP K K + T + S
Sbjct: 191 PVKKSIRDTPAKNAQKSNQNGKDS-------KPSSTPRSKGQESFKKQEKTPKTPKGPSS 243
Query: 153 LKNIRNSMRA 162
+++I+ M+A
Sbjct: 244 VEDIKAKMQA 253
Score = 28.5 bits (62), Expect = 9.0
Identities = 31/163 (19%), Positives = 60/163 (36%), Gaps = 18/163 (11%)
Query: 53 SGLVNVPEEPIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRS 112
SG V++ + + EE+ E E+EEEE+ + + + K+ + +
Sbjct: 106 SGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDD 165
Query: 113 SASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKN 172
D DE D D + + DE + ++ S+R ++ N
Sbjct: 166 DDDEEDDDEDDDDDD-----------------FDDEEAEEKAPVKKSIRDTPAKNAQKSN 208
Query: 173 RIGNKLPPEKFADVRHLLDEKRQHSRPRPPVS-STKSDIRQRL 214
+ G P + K+Q P+ P S+ DI+ ++
Sbjct: 209 QNGKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKM 251
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 45.8 bits (107), Expect = 5e-05
Identities = 44/203 (21%), Positives = 83/203 (40%), Gaps = 18/203 (8%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHE---ELPALKQPRERSASRRSSASSSDSD 120
+EE E + +E +EED+D D R V LPA + R +S +R + + D
Sbjct: 197 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTR--TEKEEERD 254
Query: 121 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 180
E + P+PK+ +K E + R ++AD + K+ ++ P
Sbjct: 255 EKEEKRLRSQTKEPTPKQKLK--------EEPDREARAGVQADEDEDGDEKDEKKHRSQP 306
Query: 181 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240
+ A R E+++ + P +S K + + +R +P++ + ++
Sbjct: 307 KDLAAKRR--PEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK---MARAKTVMN 361
Query: 241 SRLGVPRQDSKGLYADTREKKSG 263
S+ P+ G Y D + K G
Sbjct: 362 SKTHPPKCIQCGQYLDDPDLKYG 384
Score = 36.2 bits (82), Expect = 0.043
Identities = 32/161 (19%), Positives = 61/161 (37%), Gaps = 26/161 (16%)
Query: 62 PIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDE 121
P EE E + E+EE++D + R+ + E P K E R+ + + ++
Sbjct: 234 PAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED 293
Query: 122 MDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPE 181
D E K S P K + +E E + ++ ++ E
Sbjct: 294 GDEKDEKKHRSQP---KDLAAKRRPEEKEPE--------------------KVNPQISDE 330
Query: 182 KFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPE 222
K D + +EKR+ + P+ P + + + + H P+
Sbjct: 331 KDEDEK---EEKRRKTTPKEPTEKKMARAKTVMNSKTHPPK 368
Score = 34.7 bits (78), Expect = 0.13
Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 59 PEEPIEEEEEEEEEEEEEEEEDQDMD-ADDRVVVEYHEELPALKQPRERSASRRSSASSS 117
P++ ++EE + E + +ED+D D D++ ++L A ++P E+ + + S
Sbjct: 270 PKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISD 329
Query: 118 DSDEMDYDLELKMISTPSPKKSMKM 142
+ DE D E + +TP KM
Sbjct: 330 EKDE-DEKEEKRRKTTPKEPTEKKM 353
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 45.8 bits (107), Expect = 5e-05
Identities = 44/203 (21%), Positives = 83/203 (40%), Gaps = 18/203 (8%)
Query: 64 EEEEEEEEEEEEEEEEDQDMDADDRVVVEYHE---ELPALKQPRERSASRRSSASSSDSD 120
+EE E + +E +EED+D D R V LPA + R +S +R + + D
Sbjct: 181 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTR--TEKEEERD 238
Query: 121 EMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPP 180
E + P+PK+ +K E + R ++AD + K+ ++ P
Sbjct: 239 EKEEKRLRSQTKEPTPKQKLK--------EEPDREARAGVQADEDEDGDEKDEKKHRSQP 290
Query: 181 EKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVH 240
+ A R E+++ + P +S K + + +R +P++ + ++
Sbjct: 291 KDLAAKRR--PEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK---MARAKTVMN 345
Query: 241 SRLGVPRQDSKGLYADTREKKSG 263
S+ P+ G Y D + K G
Sbjct: 346 SKTHPPKCIQCGQYLDDPDLKYG 368
Score = 36.2 bits (82), Expect = 0.043
Identities = 32/161 (19%), Positives = 61/161 (37%), Gaps = 26/161 (16%)
Query: 62 PIEEEEEEEEEEEEEEEEDQDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDE 121
P EE E + E+EE++D + R+ + E P K E R+ + + ++
Sbjct: 218 PAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED 277
Query: 122 MDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPE 181
D E K S P K + +E E + ++ ++ E
Sbjct: 278 GDEKDEKKHRSQP---KDLAAKRRPEEKEPE--------------------KVNPQISDE 314
Query: 182 KFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPE 222
K D + +EKR+ + P+ P + + + + H P+
Sbjct: 315 KDEDEK---EEKRRKTTPKEPTEKKMARAKTVMNSKTHPPK 352
Score = 34.7 bits (78), Expect = 0.13
Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 59 PEEPIEEEEEEEEEEEEEEEEDQDMD-ADDRVVVEYHEELPALKQPRERSASRRSSASSS 117
P++ ++EE + E + +ED+D D D++ ++L A ++P E+ + + S
Sbjct: 254 PKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISD 313
Query: 118 DSDEMDYDLELKMISTPSPKKSMKM 142
+ DE D E + +TP KM
Sbjct: 314 EKDE-DEKEEKRRKTTPKEPTEKKM 337
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.124 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,747,841
Number of Sequences: 37866
Number of extensions: 811414
Number of successful extensions: 28115
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 722
Number of HSP's successfully gapped in prelim test: 502
Number of HSP's that attempted gapping in prelim test: 8830
Number of HSP's gapped (non-prelim): 8214
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.