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Search of human proteins with 8922733
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
(495 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|209977080 REST corepressor 3 isoform a [Homo sapiens] 1013 0.0
gi|8922733 REST corepressor 3 isoform d [Homo sapiens] 1013 0.0
gi|209977084 REST corepressor 3 isoform c [Homo sapiens] 779 0.0
gi|209977082 REST corepressor 3 isoform b [Homo sapiens] 620 e-178
gi|27734799 REST corepressor 2 [Homo sapiens] 546 e-155
gi|7661892 REST corepressor 1 [Homo sapiens] 484 e-136
gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens] 124 3e-28
gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens] 124 3e-28
gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo sapi... 124 3e-28
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 115 1e-25
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 112 8e-25
gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens] 99 9e-21
gi|14141170 metastasis-associated protein 2 [Homo sapiens] 65 2e-10
gi|15812226 transcriptional regulating factor 1 [Homo sapiens] 64 2e-10
gi|210031154 zinc finger protein 541 [Homo sapiens] 64 2e-10
gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens] 63 7e-10
gi|94721313 mesoderm induction early response 1, family member 3... 62 1e-09
gi|115527080 metastasis associated protein [Homo sapiens] 57 3e-08
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 56 9e-08
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 56 9e-08
gi|45267839 mesoderm induction early response 1, family member 2... 56 9e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 54 3e-07
gi|153792074 proline rich 12 [Homo sapiens] 54 3e-07
gi|116284392 mucin 2 precursor [Homo sapiens] 53 7e-07
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 52 1e-06
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 52 1e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 52 1e-06
gi|160707881 formin 2 [Homo sapiens] 52 2e-06
gi|210032580 SET domain containing 1B [Homo sapiens] 52 2e-06
gi|112807226 hypothetical protein LOC91748 [Homo sapiens] 52 2e-06
>gi|209977080 REST corepressor 3 isoform a [Homo sapiens]
Length = 553
Score = 1013 bits (2620), Expect = 0.0
Identities = 495/495 (100%), Positives = 495/495 (100%)
Query: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 60
MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ
Sbjct: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 118
Query: 61 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 120
ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI
Sbjct: 119 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 178
Query: 121 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 180
ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK
Sbjct: 179 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 238
Query: 181 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 240
KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT
Sbjct: 239 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 298
Query: 241 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 300
ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ
Sbjct: 299 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 358
Query: 301 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 360
GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL
Sbjct: 359 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 418
Query: 361 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP 420
GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP
Sbjct: 419 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP 478
Query: 421 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 480
TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP
Sbjct: 479 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 538
Query: 481 PSLIGIQTDSQSSLH 495
PSLIGIQTDSQSSLH
Sbjct: 539 PSLIGIQTDSQSSLH 553
>gi|8922733 REST corepressor 3 isoform d [Homo sapiens]
Length = 495
Score = 1013 bits (2620), Expect = 0.0
Identities = 495/495 (100%), Positives = 495/495 (100%)
Query: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 60
MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ
Sbjct: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 60
Query: 61 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 120
ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI
Sbjct: 61 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 120
Query: 121 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 180
ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK
Sbjct: 121 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 180
Query: 181 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 240
KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT
Sbjct: 181 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 240
Query: 241 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 300
ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ
Sbjct: 241 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 300
Query: 301 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 360
GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL
Sbjct: 301 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 360
Query: 361 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP 420
GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP
Sbjct: 361 GEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP 420
Query: 421 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 480
TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP
Sbjct: 421 TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 480
Query: 481 PSLIGIQTDSQSSLH 495
PSLIGIQTDSQSSLH
Sbjct: 481 PSLIGIQTDSQSSLH 495
>gi|209977084 REST corepressor 3 isoform c [Homo sapiens]
Length = 449
Score = 779 bits (2011), Expect = 0.0
Identities = 381/381 (100%), Positives = 381/381 (100%)
Query: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 60
MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ
Sbjct: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 118
Query: 61 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 120
ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI
Sbjct: 119 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 178
Query: 121 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 180
ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK
Sbjct: 179 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 238
Query: 181 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 240
KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT
Sbjct: 239 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 298
Query: 241 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 300
ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ
Sbjct: 299 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 358
Query: 301 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 360
GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL
Sbjct: 359 GVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTL 418
Query: 361 GEETKSASNVPSGKSTDEEEE 381
GEETKSASNVPSGKSTDEEEE
Sbjct: 419 GEETKSASNVPSGKSTDEEEE 439
>gi|209977082 REST corepressor 3 isoform b [Homo sapiens]
Length = 436
Score = 620 bits (1600), Expect = e-178
Identities = 301/306 (98%), Positives = 302/306 (98%)
Query: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVEQ 60
MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDA+LDEYIAIAKEKHGYNVEQ
Sbjct: 59 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDARLDEYIAIAKEKHGYNVEQ 118
Query: 61 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 120
ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI
Sbjct: 119 ALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTI 178
Query: 121 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 180
ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK
Sbjct: 179 ASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAK 238
Query: 181 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 240
KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT
Sbjct: 239 KEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANT 298
Query: 241 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 300
ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ
Sbjct: 299 ILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQ 358
Query: 301 GVRKYG 306
G G
Sbjct: 359 GTDPTG 364
Score = 38.1 bits (87), Expect = 0.019
Identities = 22/103 (21%), Positives = 47/103 (45%), Gaps = 2/103 (1%)
Query: 290 WTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQG 349
WT E+++L Q +GK F I ++ +KT+ + ++ ++++ + ++ +
Sbjct: 147 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLA 206
Query: 350 TQASNGDASTLGEETKSASNVPSGKSTDEE--EEAQTPQAPRT 390
+ + GD+ EET S +E +E T Q +T
Sbjct: 207 NRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQT 249
>gi|27734799 REST corepressor 2 [Homo sapiens]
Length = 523
Score = 546 bits (1408), Expect = e-155
Identities = 295/491 (60%), Positives = 362/491 (73%), Gaps = 29/491 (5%)
Query: 1 MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 59
+RVG YQA IPE P + +Y++K+ GMLVWSP H + DAKLD+YIA+AKEKHGYN+E
Sbjct: 46 IRVGTNYQAVIPECKPESPARYSNKELKGMLVWSPNHCVSDAKLDKYIAMAKEKHGYNIE 105
Query: 60 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 119
QALGML WHKH++EKSLADL NFTPFPDEWTVEDKVLFEQAF FHGK F RIQQMLPDK
Sbjct: 106 QALGMLLWHKHDVEKSLADLANFTPFPDEWTVEDKVLFEQAFGFHGKCFQRIQQMLPDKL 165
Query: 120 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDP-KKE 178
I SLVKYYYSWKKTRSRTS+MDRQAR+L R ++ DS D++EE G S+ +P +
Sbjct: 166 IPSLVKYYYSWKKTRSRTSVMDRQARRLGGRKDKEDS-DELEEGR---GGVSEGEPDPAD 221
Query: 179 AKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAA 238
K+E +P+ ++ G G++E Q Q+RHH R++ RPPKGMYL+ E + AVS SP+ A
Sbjct: 222 PKREPLPSRPL-NARPGPGKKEVQVSQYRHHPLRTRRRPPKGMYLSPEGLTAVSGSPDLA 280
Query: 239 NTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLA 298
N LR LD +LISLKRQVQ+ KQ NS+L+Q +EGGI+ +PPE+N K N+RWTT+EQLLA
Sbjct: 281 NLTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPEANTKFNSRWTTDEQLLA 340
Query: 299 VQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDAS 358
VQ +R+YGKDF AIA+VIGNKT+ QVK FFV+YRRRFNLEEVLQEWEAEQ A
Sbjct: 341 VQAIRRYGKDFGAIAEVIGNKTLTQVKTFFVSYRRRFNLEEVLQEWEAEQDGAPG---AP 397
Query: 359 TLGEETKSASNVPSGKSTDEEEEAQ----TPQAPRTLGPSPPAPSSTPTPTAPIATLNQP 414
EE + + +P+ + +E++E Q + PR++ P+PP P P PT +L+QP
Sbjct: 398 VPMEEARRGAPLPA-PALEEDDEVQITSVSTSVPRSVPPAPPPP---PPPT----SLSQP 449
Query: 415 PPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLST 474
PPLLRP LP AP L RQPPPL QQ RF+QPR NQPPPPLIRPA + PR + RP
Sbjct: 450 PPLLRPPLPTAPTLLRQPPPL-QQGRFLQPRLAPNQPPPPLIRPALA-APRHSARP---- 503
Query: 475 VGGQQPPSLIG 485
G Q PP+LIG
Sbjct: 504 -GPQPPPTLIG 513
>gi|7661892 REST corepressor 1 [Homo sapiens]
Length = 482
Score = 484 bits (1245), Expect = e-136
Identities = 248/384 (64%), Positives = 305/384 (79%), Gaps = 16/384 (4%)
Query: 1 MRVGAEYQARIPEFDPG--ATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNV 58
MRVG +YQA +P+FDP A + ++DN GMLVWSP ++ +AKLDEYIAIAKEKHGYN+
Sbjct: 102 MRVGPQYQAVVPDFDPAKLARRSQERDNLGMLVWSPNQNLSEAKLDEYIAIAKEKHGYNM 161
Query: 59 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDK 118
EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGK+FHRIQQMLPDK
Sbjct: 162 EQALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKTFHRIQQMLPDK 221
Query: 119 TIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKE 178
+IASLVK+YYSWKKTR++TS+MDR ARK + + +S+D++EE + + D + D KE
Sbjct: 222 SIASLVKFYYSWKKTRTKTSVMDRHARK--QKREREESEDELEEANGNNPIDIEVDQNKE 279
Query: 179 AKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAA 238
+KKE + V K +E S Q ++ R+K +PPKGM+L+QEDV AVS + AA
Sbjct: 280 SKKEVPPTETVPQVK-----KEKHSTQAKN---RAKRKPPKGMFLSQEDVEAVSANATAA 331
Query: 239 NTILRQLDMELISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLA 298
T+LRQLDMEL+S+KRQ+QN KQ NSALK+K++GGIE ++ PE QK NARWTTEEQLLA
Sbjct: 332 TTVLRQLDMELVSVKRQIQNIKQTNSALKEKLDGGIEPYRLPEVIQKCNARWTTEEQLLA 391
Query: 299 VQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDAS 358
VQ +RKYG+DFQAI+DVIGNK+V QVKNFFVNYRRRFN++EVLQEWEAE G + +NG ++
Sbjct: 392 VQAIRKYGRDFQAISDVIGNKSVVQVKNFFVNYRRRFNIDEVLQEWEAEHGKEETNGPSN 451
Query: 359 TLGEETKSASNVPSGKSTDEEEEA 382
+ KS N S K +EE+EA
Sbjct: 452 Q--KPVKSPDN--SIKMPEEEDEA 471
>gi|169204926 PREDICTED: similar to hCG2041217 [Homo sapiens]
Length = 266
Score = 124 bits (310), Expect = 3e-28
Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%)
Query: 1 MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 59
+RVG YQA IPE P + +Y++K G+LVWSP H + DAKLD+YI +A EKHGYN+E
Sbjct: 2 VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61
Query: 60 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 119
Q LG+ + + L LP W IQQ LPDK
Sbjct: 62 QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94
Query: 120 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 178
I+SLVKY+YSWKKT SRTS+ DRQAR+L ++ DSD+ E + + D PK+E
Sbjct: 95 ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154
Score = 72.8 bits (177), Expect = 7e-13
Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%)
Query: 308 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 367
DF AIA+VIGNKT+ QVK FFV+Y FNLEEVLQEWEAEQ + G + E + A
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226
Query: 368 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 406
+ + +E+ E Q ++ S PP + P PT+
Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264
>gi|169205586 PREDICTED: similar to hCG2041217 [Homo sapiens]
Length = 266
Score = 124 bits (310), Expect = 3e-28
Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%)
Query: 1 MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 59
+RVG YQA IPE P + +Y++K G+LVWSP H + DAKLD+YI +A EKHGYN+E
Sbjct: 2 VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61
Query: 60 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 119
Q LG+ + + L LP W IQQ LPDK
Sbjct: 62 QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94
Query: 120 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 178
I+SLVKY+YSWKKT SRTS+ DRQAR+L ++ DSD+ E + + D PK+E
Sbjct: 95 ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154
Score = 72.8 bits (177), Expect = 7e-13
Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%)
Query: 308 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 367
DF AIA+VIGNKT+ QVK FFV+Y FNLEEVLQEWEAEQ + G + E + A
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226
Query: 368 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 406
+ + +E+ E Q ++ S PP + P PT+
Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264
>gi|169203873 PREDICTED: similar to REST corepressor 2 [Homo
sapiens]
Length = 266
Score = 124 bits (310), Expect = 3e-28
Identities = 78/180 (43%), Positives = 101/180 (56%), Gaps = 29/180 (16%)
Query: 1 MRVGAEYQARIPEFDPGA-TKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNVE 59
+RVG YQA IPE P + +Y++K G+LVWSP H + DAKLD+YI +A EKHGYN+E
Sbjct: 2 VRVGTNYQAIIPECKPESLARYSNKKLKGVLVWSPNHCVSDAKLDKYIVMATEKHGYNIE 61
Query: 60 QALGMLFWHKHNIEKSLADLPNFTPFPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKT 119
Q LG+ + + L LP W IQQ LPDK
Sbjct: 62 QTLGVDSRGQGAVGTGLW-LPR-----QVW---------------------IQQTLPDKL 94
Query: 120 IASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEETHPMDGNDSDY-DPKKE 178
I+SLVKY+YSWKKT SRTS+ DRQAR+L ++ DSD+ E + + D PK+E
Sbjct: 95 ISSLVKYHYSWKKTHSRTSMTDRQARRLRGCKDKEDSDEFEESRGGLSEGEPDAGHPKRE 154
Score = 72.8 bits (177), Expect = 7e-13
Identities = 44/100 (44%), Positives = 58/100 (58%), Gaps = 5/100 (5%)
Query: 308 DFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSA 367
DF AIA+VIGNKT+ QVK FFV+Y FNLEEVLQEWEAEQ + G + E + A
Sbjct: 169 DFGAIAEVIGNKTLTQVKTFFVSYWHCFNLEEVLQEWEAEQ--DGARGATVPVEEARRGA 226
Query: 368 SNVPSGKSTDEEEEAQTPQAPRTLGPS-PPAPSSTPTPTA 406
+ + +E+ E Q ++ S PP + P PT+
Sbjct: 227 PLL--APAQEEDHEVQITSISMSVSRSVPPCTTPVPPPTS 264
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 115 bits (287), Expect = 1e-25
Identities = 107/410 (26%), Positives = 167/410 (40%), Gaps = 39/410 (9%)
Query: 89 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 145
W+ ++K F + F H K+F I L KT+A V YYY KK + SL+ R R
Sbjct: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
Query: 146 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSLQ 205
K + Q ++ PM + + +KE +KE E+ + E ++
Sbjct: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEE---------KPEVEN-- 540
Query: 206 HRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNSA 265
+ + K G +++ VA S AN+ R+ + R + N A
Sbjct: 541 DKEDLLKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANSEEA 595
Query: 266 LKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVK 325
+ + + + ES+ RWT EE A +G+ ++G+++ AIA ++G+KTV Q K
Sbjct: 596 ITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCK 650
Query: 326 NFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------PSGK 374
NF+ NY++R NL+E+LQ+ E E+ + A E + V SG
Sbjct: 651 NFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGV 710
Query: 375 STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP 434
S +EEE + +A + S T A N P P P PPP
Sbjct: 711 SGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPP 770
Query: 435 LQQQARFIQPRP---TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 481
A +P P P PP P+ S PP + P+ PP
Sbjct: 771 EDIPAP-TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPP 819
Score = 42.4 bits (98), Expect = 0.001
Identities = 89/439 (20%), Positives = 152/439 (34%), Gaps = 108/439 (24%)
Query: 89 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLA 148
WT E+ ++ HG+++ I +M+ KT++ +Y+++KK ++ ++ + K+
Sbjct: 615 WTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQNLDEILQQHKLKME 674
Query: 149 NRHN--------------------------------QGDSDDDVEETHPMDGNDSDYD-- 174
N G+ ++ VEE N SD +
Sbjct: 675 KERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNSSDTESI 734
Query: 175 --PKKEAKKEGNTEQPVQTSKIGLGRREYQSLQHRHHSQRSKCRPPKGMYLTQEDVVAVS 232
P EA K+ P + +G PP G + +
Sbjct: 735 PSPHTEAAKDTGQNGPKPPATLGADG------------------PPPGPPTPPPEDIPAP 776
Query: 233 CSPNAANTILRQLDMELISLKRQV------QNAKQVNSALKQKMEGGIEEFKPPESNQKI 286
P A+ + K+ +A +E G EE KPP + +
Sbjct: 777 TEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEG-EEQKPPAAEELA 835
Query: 287 NARWTTEEQLL------AVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEV 340
EE + A +G K GKD +A E
Sbjct: 836 VDTGKAEEPVKSECTEEAEEGPAK-GKDAEAA---------------------EATAEGA 873
Query: 341 LQEWEAEQGT-QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPS 399
L+ + E G+ +A+ +S +++ S++ S DE +EA+ R L P P
Sbjct: 874 LKAEKKEGGSGRATTAKSSGAPQDSDSSATC----SADEVDEAEGGDKNRLLSPRP---- 925
Query: 400 STPTPTA-PIATLNQPPPL----LRPTLPAAPALH--RQPPPLQQQARFIQPRPTLNQPP 452
S TPT P A + PL L+ A P + + P ++ A +P P PP
Sbjct: 926 SLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPA-PPP 984
Query: 453 PPLIRPANSMP--PRLNPR 469
P ++P + P P +PR
Sbjct: 985 PQNLQPESDAPQQPGSSPR 1003
Score = 38.1 bits (87), Expect = 0.019
Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 6/118 (5%)
Query: 348 QGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPSSTP 402
Q Q + G + S P+ + E E+ A +A + G P S P
Sbjct: 986 QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLP 1045
Query: 403 TPTAPIATLNQPPPLLRPT-LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPA 459
P P + P P+ AP H P L AR + PRP PPPLI A
Sbjct: 1046 FPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1103
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 112 bits (280), Expect = 8e-25
Identities = 105/410 (25%), Positives = 167/410 (40%), Gaps = 49/410 (11%)
Query: 89 WTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQAR--- 145
W+ ++K F + F H K+F I L KT+A V YYY KK + SL+ R R
Sbjct: 432 WSEQEKETFREKFMQHPKNFGLIASFLERKTVAECVLYYYLTKKNENYKSLVRRSYRRRG 491
Query: 146 KLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSLQ 205
K + Q ++ PM + + +KE +KE E+ + E ++
Sbjct: 492 KSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEKEKEKEAEKEEE---------KPEVEN-- 540
Query: 206 HRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNSA 265
+ + K G +++ VA S AN+ R+ + R + N A
Sbjct: 541 DKEDLLKEKTDDTSGEDNDEKEAVA-SKGRKTANSQGRRKGR----ITRSMANEANSEEA 595
Query: 266 LKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVK 325
+ + + + ES+ RWT EE A +G+ ++G+++ AIA ++G+KTV Q K
Sbjct: 596 ITPQQSAELASMELNESS-----RWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCK 650
Query: 326 NFFVNYRRRFNLEEVLQE----WEAEQGTQASNGDASTLGEETKSASNV-------PSGK 374
NF+ NY++R NL+E+LQ+ E E+ + A E + V SG
Sbjct: 651 NFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGV 710
Query: 375 STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP 434
S +EEE + +A G P + T ++ + P P AA + P
Sbjct: 711 SGNEEEMVEEAEALHASGNEVPRGECSGPATVNNSSDTESIP--SPHTEAAKDTGQNGP- 767
Query: 435 LQQQARFIQPRPTL---NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 481
+P TL PP P P +P P P G PP
Sbjct: 768 --------KPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP 809
Score = 38.1 bits (87), Expect = 0.019
Identities = 33/118 (27%), Positives = 43/118 (36%), Gaps = 6/118 (5%)
Query: 348 QGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPSSTP 402
Q Q + G + S P+ + E E+ A +A + G P S P
Sbjct: 1002 QNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLP 1061
Query: 403 TPTAPIATLNQPPPLLRPT-LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPA 459
P P + P P+ AP H P L AR + PRP PPPLI A
Sbjct: 1062 FPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPPLISSA 1119
Score = 32.7 bits (73), Expect = 0.78
Identities = 37/138 (26%), Positives = 56/138 (40%), Gaps = 13/138 (9%)
Query: 343 EWEAEQGTQASNGDASTLGEETKSASNVPSGK------STDEEEEAQTPQAPRTLGPSPP 396
E AE +A + + T +S P S DE +EA+ R L P P
Sbjct: 884 EATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPS 943
Query: 397 APSSTPTPTAPIATLNQPPPLLRPTLPAA---PALHRQPPPLQQQARFIQPRPTLNQPPP 453
+ T P A A+ +P L + AA P + + P ++ A +P P PPP
Sbjct: 944 LLTPTGDPRAN-ASPQKPLDLKQLKQRAAAIPPIVTKVHEPPREDAAPTKPAPPA-PPPP 1001
Query: 454 PLIRPANSMP--PRLNPR 469
++P + P P +PR
Sbjct: 1002 QNLQPESDAPQQPGSSPR 1019
Score = 31.6 bits (70), Expect = 1.7
Identities = 23/83 (27%), Positives = 32/83 (38%), Gaps = 12/83 (14%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLL----- 418
T A P G T E+ P P + AP+ P P +P A PPP++
Sbjct: 772 TLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSA----PPPVVPKEEK 827
Query: 419 RPTLPAAPAL---HRQPPPLQQQ 438
AAP + Q PP ++
Sbjct: 828 EEETAAAPPVEEGEEQKPPAAEE 850
>gi|22538461 nuclear receptor co-repressor 1 [Homo sapiens]
Length = 2440
Score = 99.0 bits (245), Expect = 9e-21
Identities = 87/353 (24%), Positives = 151/353 (42%), Gaps = 31/353 (8%)
Query: 85 FPDEWTVEDKVLFEQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQA 144
F + WT +K +F+ F H K+F I L K++ V YYY KK + +L+ R
Sbjct: 436 FMNVWTDHEKEIFKDKFIQHPKNFGLIASYLERKSVPDCVLYYYLTKKNENYKALVRRNY 495
Query: 145 RKLANRHNQGDSDDDVEETHPMDGNDSDYDPKKEAKKEGNTEQPVQTSKIGLGRREYQSL 204
K R+ Q E+ + + ++ KKE +K+ E+ +
Sbjct: 496 GKRRGRNQQIARPSQEEKVEEKEEDKAEKTEKKEEEKKDEEEKDEK-------------- 541
Query: 205 QHRHHSQRSKCRPPKGMYLTQEDVVAVSCSPNAANTILRQLDMELISLKRQVQNAKQVNS 264
+ + + K + T+E A AN+ R+ S+ + A +
Sbjct: 542 EDSKENTKEKDKIDGTAEETEEREQATPRGRKTANSQGRRKGRITRSMTNEAAAASAAAA 601
Query: 265 ALKQKMEGGIEEFKPPESNQKIN-ARWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQ 323
A ++ + P S + + +RWT EE +A +G+ ++G+++ AIA ++G K+ Q
Sbjct: 602 AATEEPPPPLPPPPEPISTEPVETSRWTEEEMEVAKKGLVEHGRNWAAIAKMVGTKSEAQ 661
Query: 324 VKNFFVNYRRRFNLEEVLQEWE--------AEQGTQASNGDASTLG---EETKSASNVPS 372
KNF+ NY+RR NL+ +LQ+ + E+ AST+ +E ASN
Sbjct: 662 CKNFYFNYKRRHNLDNLLQQHKQKTSRKPREERDVSQCESVASTVSAQEDEDIEASNEEE 721
Query: 373 GKSTDEEEEAQ----TPQAPRTLGPSPPAPSSTP-TPTAPIATLNQPPPLLRP 420
E E + +P+ + G + PA P T TAP + + P +P
Sbjct: 722 NPEDSEVEAVKPSEDSPENATSRGNTEPAVELEPTTETAPSTSPSLAVPSTKP 774
>gi|14141170 metastasis-associated protein 2 [Homo sapiens]
Length = 668
Score = 64.7 bits (156), Expect = 2e-10
Identities = 44/167 (26%), Positives = 81/167 (48%), Gaps = 34/167 (20%)
Query: 1 MRVGAEYQARIPE-FDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKE------- 52
+RVG +YQA IP+ G + ++ M VW P + + D ++D+++ +A+
Sbjct: 147 IRVGCKYQAEIPDRLVEGESDNRNQQKMEMKVWDPDNPLTDRQIDQFLVVARAVGTFARA 206
Query: 53 -------------------KHGYNVEQALGMLFWHKHNIEKSLADL-PNFTPF-----PD 87
+ A+ L + +++ K+++ L P P +
Sbjct: 207 LDCSSSIRQPSLHMSAAAASRDITLFHAMDTLQRNGYDLAKAMSTLVPQGGPVLCRDEME 266
Query: 88 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 133
EW+ + +LFE+A +GK F+ I+Q LP K++AS+V++YY WK T
Sbjct: 267 EWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTT 313
Score = 29.6 bits (65), Expect = 6.6
Identities = 17/61 (27%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 290 WTTEEQLLAVQGVRKYGKDFQAI-ADVIGNKTVGQVKNFFVNYRR--RFNLEEVLQEWEA 346
W+ E +L + + KYGKDF I D + K++ + F+ ++ R+ ++ L+ EA
Sbjct: 268 WSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEA 327
Query: 347 E 347
+
Sbjct: 328 D 328
>gi|15812226 transcriptional regulating factor 1 [Homo sapiens]
Length = 1200
Score = 64.3 bits (155), Expect = 2e-10
Identities = 55/210 (26%), Positives = 92/210 (43%), Gaps = 28/210 (13%)
Query: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYI--------AIAKE 52
+ +G +QA IPE + D LVW P+ + + L + + + A
Sbjct: 781 INIGLRFQAEIPELQDISALAQDTHKA-TLVWKPWPELENHDLQQRVENLLNLCCSSALP 839
Query: 53 KHGYNVEQALGMLFWHKHNIEKSLADLPNFTPF--------------PDEWTVEDKVLFE 98
G N E AL LF K ++ +L L P D+WT ++ LF
Sbjct: 840 GGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFN 899
Query: 99 QAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDD 158
+A + + K F +Q+M+ KT+A V+YYY+WKK L + +LA + + +
Sbjct: 900 KALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKI---MRLGRKHRTRLAEIIDDCVTSE 956
Query: 159 DVEETHPMDGNDSDYDPKKEAKKEGNTEQP 188
+ EE + D + D +++ KE +E P
Sbjct: 957 EEEELEEEEEEDPEED--RKSTKEEESEVP 984
Score = 52.4 bits (124), Expect = 9e-07
Identities = 39/152 (25%), Positives = 64/152 (42%), Gaps = 5/152 (3%)
Query: 289 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 348
+WT+ E+ L + + Y KDF + ++ +KTV Q ++ +++ L + AE
Sbjct: 889 KWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEI 948
Query: 349 GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPI 408
+ EE + KST +EEE++ P++P PP P PT P+
Sbjct: 949 IDDCVTSEEEEELEEEEEEDPEEDRKST-KEEESEVPKSPE----PPPVPVLAPTEGPPL 1003
Query: 409 ATLNQPPPLLRPTLPAAPALHRQPPPLQQQAR 440
L QP +P A+ L AR
Sbjct: 1004 QALGQPSGSFICEMPNCGAVFSSRQALNGHAR 1035
Score = 31.2 bits (69), Expect = 2.3
Identities = 32/137 (23%), Positives = 45/137 (32%), Gaps = 40/137 (29%)
Query: 377 DEEEEAQTPQAPRTLGPSPPAPSSTPTP------TAPIATLNQPPPLLRP---------T 421
+E E+ PQ L P PP P P T + ++ P LL P +
Sbjct: 546 EEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNS 605
Query: 422 LPAAPALHRQP----------------------PPLQQQARFIQPRPTLNQPPPPLIRPA 459
AAP+ +P P ++ + +Q + P PL P
Sbjct: 606 TVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPP 665
Query: 460 NSMPPRLNPRPVLSTVG 476
PP NP P S G
Sbjct: 666 ---PPSYNPNPAASYSG 679
>gi|210031154 zinc finger protein 541 [Homo sapiens]
Length = 1365
Score = 64.3 bits (155), Expect = 2e-10
Identities = 48/155 (30%), Positives = 72/155 (46%), Gaps = 24/155 (15%)
Query: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPY-----HSIPDAKLDEYIAIAKEK-- 53
+ +G+ +QA IPE + TD ++ LVW P+ S ++ E +A
Sbjct: 1074 INIGSRFQAEIPELQERSLAGTD-EHVASLVWKPWGDMMISSETQDRVTELCNVACSSVM 1132
Query: 54 --HGYNVEQALGMLFWHKHNIEKSLADLPNFTPFP--------------DEWTVEDKVLF 97
G N+E AL L + N++ +L L P D WT +K LF
Sbjct: 1133 PGGGTNLELALHCLHEAQGNVQVALETLLLRGPHKPRTHLLADYRYTGSDVWTPIEKRLF 1192
Query: 98 EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 132
++AF H K F+ I +M+ KT+A V+YYY WKK
Sbjct: 1193 KKAFYAHKKDFYLIHKMIQTKTVAQCVEYYYIWKK 1227
>gi|50838795 metastasis associated 1 family, member 3 [Homo sapiens]
Length = 515
Score = 62.8 bits (151), Expect = 7e-10
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 34/167 (20%)
Query: 1 MRVGAEYQARIPEFD-PGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 56
+RVG YQA IPE G + ++ + VW P + D ++D+++ +A+ +
Sbjct: 150 IRVGPRYQADIPEMLLEGESDEREQSKLEVKVWDPNSPLTDRQIDQFLVVARAVGTFARA 209
Query: 57 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 87
+V Q A+ L+ H +++ +++ L P P +
Sbjct: 210 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHSYDLSSAISVLVPLGGPVLCRDEME 269
Query: 88 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 133
EW+ + LFE+A +GK F+ I+Q LP K++ S+++YYY WK T
Sbjct: 270 EWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT 316
>gi|94721313 mesoderm induction early response 1, family member 3
[Homo sapiens]
Length = 549
Score = 62.0 bits (149), Expect = 1e-09
Identities = 56/193 (29%), Positives = 85/193 (44%), Gaps = 32/193 (16%)
Query: 3 VGAEYQARIP----EFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIA---------- 48
+G +YQA IP E+D Y ++D L+W P + ++K+ EY+
Sbjct: 178 IGLQYQAEIPPYLGEYDGNEKVYENEDQ---LLWCP-DVVLESKVKEYLVETSLRTGSEK 233
Query: 49 ----IAKEKHGYNVEQALGMLFWHKHNIEKSLADL---PNFTPFPDEWTVEDKVLFEQAF 101
I+ H + EQAL L HNI++++ + WT E+ FE A
Sbjct: 234 IMDRISAGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQGMTAWTEEECRSFEHAL 293
Query: 102 SFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDD- 159
GK FH IQ+ + +T+A V +YY WKK+ R +Q R R+N D
Sbjct: 294 MLFGKDFHLIQKNKVRTRTVAECVAFYYMWKKS-ERYDYFAQQTRFGKKRYNHHPGVTDY 352
Query: 160 ----VEETHPMDG 168
V+ET + G
Sbjct: 353 MDRLVDETEALGG 365
>gi|115527080 metastasis associated protein [Homo sapiens]
Length = 715
Score = 57.4 bits (137), Expect = 3e-08
Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 34/167 (20%)
Query: 1 MRVGAEYQARIPEF-DPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGY--- 56
+RVG YQA I + G D+ VW ++ + D ++D+++ +A+ +
Sbjct: 167 IRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARA 226
Query: 57 -----NVEQ------------------ALGMLFWHKHNIEKSLADL-PNFTPF-----PD 87
+V Q A+ L + ++I K+++ L P P +
Sbjct: 227 LDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEME 286
Query: 88 EWTVEDKVLFEQAFSFHGKSFHRIQQ-MLPDKTIASLVKYYYSWKKT 133
EW+ + LFE+A +GK F IQQ LP K++ S+++YYY WK T
Sbjct: 287 EWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTT 333
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 55.8 bits (133), Expect = 9e-08
Identities = 64/247 (25%), Positives = 97/247 (39%), Gaps = 42/247 (17%)
Query: 250 ISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVR--KYGK 307
+S K++ + A + + K G F P + N + A+ + E + V+ K
Sbjct: 399 LSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAP 458
Query: 308 DFQAI------ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG 361
D + + +V + G+VK N E+ L + QGT+ S A L
Sbjct: 459 DTELVNVTHLNTEVKNSSDTGKVK-------LDENSEKHLVKDLKAQGTRDSKPIA--LK 509
Query: 362 EETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPT 421
EE + + K T+ E+ P P P PP P++TP P Q PPL P
Sbjct: 510 EE------IVTPKETETSEKETPPPLPTIASPPPPLPTTTPPP--------QTPPL--PP 553
Query: 422 LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 481
LP PAL +QPP Q F Q + PP S +S+ QPP
Sbjct: 554 LPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTS---------AVSSQANSQPP 604
Query: 482 SLIGIQT 488
+ ++T
Sbjct: 605 VQVSVKT 611
Score = 35.4 bits (80), Expect = 0.12
Identities = 39/161 (24%), Positives = 56/161 (34%), Gaps = 21/161 (13%)
Query: 321 VGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG--EETKSASN----VPSGK 374
+ Q+ N N + LE + Q A + D+ T+ E K A + +PS +
Sbjct: 1134 MAQLLNIHSNPEMQQQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAE 1193
Query: 375 STDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPP------PLLRPTLPAAPAL 428
T E + L T P + N P PT+P A
Sbjct: 1194 QTTLEASSTPADMQNILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAA 1253
Query: 429 HRQPPPLQQQARFIQPRPTLNQPPPPLIR-PANSMPPRLNP 468
++PP P P PPPPL+ +S P LNP
Sbjct: 1254 EKRPPE--------PPGPPPPPPPPPLVEGDLSSAPQELNP 1286
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 55.8 bits (133), Expect = 9e-08
Identities = 64/247 (25%), Positives = 97/247 (39%), Gaps = 42/247 (17%)
Query: 250 ISLKRQVQNAKQVNSALKQKMEGGIEEFKPPESNQKINARWTTEEQLLAVQGVR--KYGK 307
+S K++ + A + + K G F P + N + A+ + E + V+ K
Sbjct: 399 LSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKDSGLESKKLPRSVKLEKSAP 458
Query: 308 DFQAI------ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLG 361
D + + +V + G+VK N E+ L + QGT+ S A L
Sbjct: 459 DTELVNVTHLNTEVKNSSDTGKVK-------LDENSEKHLVKDLKAQGTRDSKPIA--LK 509
Query: 362 EETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPT 421
EE + + K T+ E+ P P P PP P++TP P Q PPL P
Sbjct: 510 EE------IVTPKETETSEKETPPPLPTIASPPPPLPTTTPPP--------QTPPL--PP 553
Query: 422 LPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 481
LP PAL +QPP Q F Q + PP S +S+ QPP
Sbjct: 554 LPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTS---------AVSSQANSQPP 604
Query: 482 SLIGIQT 488
+ ++T
Sbjct: 605 VQVSVKT 611
Score = 30.8 bits (68), Expect = 3.0
Identities = 26/78 (33%), Positives = 28/78 (35%), Gaps = 24/78 (30%)
Query: 395 PPAPSSTPTPTAPIATLNQP---PPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQP 451
P P TPT A P PP RP P P PPP P
Sbjct: 1238 PQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGP-----PPP---------------PP 1277
Query: 452 PPPLIR-PANSMPPRLNP 468
PPPL+ +S P LNP
Sbjct: 1278 PPPLVEGDLSSAPQELNP 1295
>gi|45267839 mesoderm induction early response 1, family member 2
[Homo sapiens]
Length = 545
Score = 55.8 bits (133), Expect = 9e-08
Identities = 51/189 (26%), Positives = 84/189 (44%), Gaps = 24/189 (12%)
Query: 3 VGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAKLDEYIAIAKEKHGYNV---- 58
VG ++QA + +N L+W P +P+ +++E++ A ++ + +
Sbjct: 199 VGPQFQADLSNLHLNRHCEKIYENEDQLLWDP-SVLPEREVEEFLYRAVKRRWHEMAGPQ 257
Query: 59 ----------EQALGMLFWHKHNIEKSLADLP-NFTPFPD---EWTVEDKVLFEQAFSFH 104
EQAL L N+E++L L N D W+ E+ FE F H
Sbjct: 258 LPEGEAVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLCAWSEEECRNFEHGFRVH 317
Query: 105 GKSFHRIQ-QMLPDKTIASLVKYYYSWKKTRSRTSLMDRQARKLANRHNQGDSDDDVEET 163
GK+FH IQ + +++ V+YYY WKK+ R +Q R L R D ++
Sbjct: 318 GKNFHLIQANKVRTRSVGECVEYYYLWKKS-ERYDYFAQQTR-LGRRKYVPSGTTDADQ- 374
Query: 164 HPMDGNDSD 172
+DG+D D
Sbjct: 375 -DLDGSDPD 382
Score = 40.4 bits (93), Expect = 0.004
Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 22/183 (12%)
Query: 290 WTTEEQLLAVQGVRKYGKDFQAI-ADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 348
W+ EE G R +GK+F I A+ + ++VG+ ++ +++ + Q+
Sbjct: 302 WSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQ----- 356
Query: 349 GTQASNGDASTLGEETKSASNVPSGKS-TDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAP 407
+ LG VPSG + D++ + P P P P + T T P
Sbjct: 357 ---------TRLGRR----KYVPSGTTDADQDLDGSDPDGPGR--PRPEQDTLTGMRTDP 401
Query: 408 IATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLN 467
++ L P + + +P P Q P L+ PP L PA+ P
Sbjct: 402 LSVDGTAGGLDEPGVASDGLPSSEPGPCSFQQLDESPAVPLSHRPPALADPASYQPAVTA 461
Query: 468 PRP 470
P P
Sbjct: 462 PEP 464
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/167 (30%), Positives = 70/167 (41%), Gaps = 34/167 (20%)
Query: 345 EAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEE-----AQTPQAPRTLGPSPPAPS 399
E+E +++S+ D+ E S ++++ Q QAP + PP P
Sbjct: 702 ESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPP 761
Query: 400 STPTPTAPIATLNQ-PPPLLRPTLP--AAPALHRQPPP--------LQQQ---------A 439
P P P Q PPP P++P AAPA+ PPP L+ Q
Sbjct: 762 QQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIG 821
Query: 440 RFIQPRPTLNQP--PPPLIR-PANSMPPRLNPRPVLSTVGGQQPPSL 483
F QP L QP PP L + P +S PP LN V+S PP+L
Sbjct: 822 HFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVS------PPAL 862
Score = 43.9 bits (102), Expect = 3e-04
Identities = 34/109 (31%), Positives = 40/109 (36%), Gaps = 19/109 (17%)
Query: 380 EEAQTPQAPRTLGPS-------PPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP 432
++ Q Q P L PS PP P P+ QPPP P P QP
Sbjct: 933 QQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQP 992
Query: 433 PPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 481
PP + +Q + QPPP P PP P GQQPP
Sbjct: 993 PPRPVHLQPMQFSTHIQQPPP----PQGQQPPHPPP--------GQQPP 1029
Score = 40.4 bits (93), Expect = 0.004
Identities = 42/159 (26%), Positives = 61/159 (38%), Gaps = 26/159 (16%)
Query: 347 EQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTL--GPSPPAPSST--- 401
+Q ++ SN A+ + + + P+ T + Q P+ L PPAP T
Sbjct: 868 QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927
Query: 402 -------------PTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTL 448
PTP P + PP P LP P P +QQQ + P P
Sbjct: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPP---PPLPPPPH-----PSVQQQLQQQPPPPPP 979
Query: 449 NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGIQ 487
QP PP + P ++ +P+ + QQPP G Q
Sbjct: 980 PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQ 1018
Score = 39.7 bits (91), Expect = 0.006
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 1/85 (1%)
Query: 385 PQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQP 444
P + L PP P P P P +QPPP P + H Q PP Q + P
Sbjct: 964 PSVQQQLQQQPPPPPP-PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHP 1022
Query: 445 RPTLNQPPPPLIRPANSMPPRLNPR 469
P PPP +P + +PR
Sbjct: 1023 PPGQQPPPPQPAKPQQVIQHHHSPR 1047
Score = 38.9 bits (89), Expect = 0.011
Identities = 39/149 (26%), Positives = 53/149 (35%), Gaps = 30/149 (20%)
Query: 361 GEETKSASNVPSGKST-DEEEEAQTPQAPRTLGPSPPAPSSTPTP----------TAPIA 409
G K G ST +A TP +T P+PP +TP P P+
Sbjct: 180 GRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVM 239
Query: 410 TLNQPPPLLRPTLPAAPALHRQPP-----PLQQQARFIQPRP-----------TLNQPPP 453
T+ P PL P P P + PP P+Q I P + P
Sbjct: 240 TVVPPQPLQTP--PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
Query: 454 PLIRPANSMPPRLNPRPVLSTVGGQQPPS 482
I P + PP L P P + +G ++ S
Sbjct: 298 TTIDPIHE-PPSLPPEPKTTKLGQRRESS 325
Score = 35.4 bits (80), Expect = 0.12
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 18/96 (18%)
Query: 393 PSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALH----RQPPPLQQQARFIQPRPTL 448
P P P P P + PP L + + + PALH +QP +A + P+P
Sbjct: 831 PQPELPPHLPQPPEH----STPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA- 885
Query: 449 NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 484
PP + PA + P L P+P ++ QPP ++
Sbjct: 886 ---RPPAVSPALTQTPLL-PQPPMA-----QPPQVL 912
Score = 30.8 bits (68), Expect = 3.0
Identities = 27/109 (24%), Positives = 37/109 (33%), Gaps = 2/109 (1%)
Query: 378 EEEEAQTPQAP-RTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQ 436
EE E QA R G + T P T PP + P P + P P
Sbjct: 167 EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP 226
Query: 437 QQAR-FIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 484
I P + PP ++ +PP+ P P + Q P +I
Sbjct: 227 AVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPII 275
Score = 30.4 bits (67), Expect = 3.9
Identities = 32/118 (27%), Positives = 39/118 (33%), Gaps = 40/118 (33%)
Query: 395 PPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQP----------------PPLQ-- 436
P PS A + PP + P L P L + P PPL
Sbjct: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSM 926
Query: 437 ------QQARFIQPRPTL-------NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 481
QQ + +QP L +QPPPPL P P P + QQPP
Sbjct: 927 QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPP---------PHPSVQQQLQQQPP 975
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 53.9 bits (128), Expect = 3e-07
Identities = 53/170 (31%), Positives = 69/170 (40%), Gaps = 30/170 (17%)
Query: 335 FNLEEVLQEWEAEQGTQASNGDASTLGEETK-SASNVPSGKSTDEEEEAQTPQAPRTLGP 393
F L L+ E+E L EE K + +PS S +E+ A+ ++
Sbjct: 1341 FGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISS 1400
Query: 394 S----------PPAPSSTPT--PTAPIATLNQPPPLLRPTLPAA--------PALHRQPP 433
+ P +STP P AP A + PPPL P LP+A P L +PP
Sbjct: 1401 AISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPL--PGLPSANSNGTPEPPLLEEKPP 1458
Query: 434 PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSL 483
P A QP+P PPPP +PA PP L V T PP L
Sbjct: 1459 PTPPPAPTPQPQP---PPPPPPPQPALPSPPPL----VAPTPSSPPPPPL 1501
Score = 48.5 bits (114), Expect = 1e-05
Identities = 32/86 (37%), Positives = 37/86 (43%), Gaps = 12/86 (13%)
Query: 378 EEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 437
EE+ TP T P PP P P P P PPPL+ PT P++P PPPL
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPALP-----SPPPLVAPT-PSSPP----PPPLPP 1503
Query: 438 QARFIQPRPTLNQPPPPLIRPANSMP 463
P P PPPP P + P
Sbjct: 1504 PPPPAMPSPP--PPPPPAAAPLAAPP 1527
Score = 48.1 bits (113), Expect = 2e-05
Identities = 31/81 (38%), Positives = 35/81 (43%), Gaps = 11/81 (13%)
Query: 384 TPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQ 443
TP+ P PP P PTP QPPP P PA P+ PPPL
Sbjct: 1447 TPEPPLLEEKPPPTPPPAPTPQP------QPPPPPPPPQPALPS----PPPLVAPTPSSP 1496
Query: 444 PRPTLNQPPPPLIRPANSMPP 464
P P L PPPP + P+ PP
Sbjct: 1497 PPPPLPPPPPPAM-PSPPPPP 1516
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/153 (26%), Positives = 55/153 (35%), Gaps = 17/153 (11%)
Query: 336 NLEEVLQEWEAEQGTQASNGDAS-TLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPS 394
NLE + E+ + A N D ++ + + P D P AP P
Sbjct: 1373 NLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPG 1432
Query: 395 PP------APSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTL 448
PP + +S TP P+ L + PP P P PPP P+P L
Sbjct: 1433 PPPLPGLPSANSNGTPEPPL--LEEKPPPTPPPAPTPQPQPPPPPP--------PPQPAL 1482
Query: 449 NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPP 481
PPP + +S PP P P + PP
Sbjct: 1483 PSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPP 1515
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 6/84 (7%)
Query: 371 PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHR 430
P T + + P P+ PSPP P PTP++P PPPL P PA P+
Sbjct: 1461 PPPAPTPQPQPPPPPPPPQPALPSPP-PLVAPTPSSP-----PPPPLPPPPPPAMPSPPP 1514
Query: 431 QPPPLQQQARFIQPRPTLNQPPPP 454
PPP P P P
Sbjct: 1515 PPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 34.3 bits (77), Expect = 0.27
Identities = 33/112 (29%), Positives = 45/112 (40%), Gaps = 18/112 (16%)
Query: 381 EAQTPQAPRTLGPSPP---------APSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQ 431
EA P P L P PP APS P+P+A ++ P R P P
Sbjct: 784 EAGGPDLPLVLPPPPPQLLPSVLSHAPS--PSPSASKVGVHLLEPATRDGAPQPPPPPPP 841
Query: 432 PP---PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 480
PP PLQ +A ++ P P +RP S+ P P + +G +P
Sbjct: 842 PPPPMPLQLEAH-LRSHGLEPAAPSPRLRPEESLDP---PGAMQELLGALEP 889
Score = 32.0 bits (71), Expect = 1.3
Identities = 30/101 (29%), Positives = 40/101 (39%), Gaps = 9/101 (8%)
Query: 371 PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP--TAPIATLNQPPPLLRPTLPAAPAL 428
P G +A P P P PPAP+S P T+PI +P LL+ + + L
Sbjct: 1026 PLGLIQSGPHQAAPPPPPPP--PPPPAPASEPKGGLTSPIFCSTKPKKLLKTS--SFHLL 1081
Query: 429 HRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPR 469
R+ PP Q + PA+ RLNPR
Sbjct: 1082 RRRDPPFQTPKKLYAQEYEFEADEDKADVPADI---RLNPR 1119
Score = 30.0 bits (66), Expect = 5.0
Identities = 30/125 (24%), Positives = 46/125 (36%), Gaps = 12/125 (9%)
Query: 374 KSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPP 433
K+T E+ QTP+ T P PPAP P+ P+ + + R P
Sbjct: 1708 KTTSEKPPEQTPE---TAMPEPPAPEK-PSLLRPVEKEKEKEKVTRGERPLRGERATSGR 1763
Query: 434 PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQ-----PPSLIGIQT 488
+ + +P ++ P + PP + L GG PP G +
Sbjct: 1764 QTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPP---GSSS 1820
Query: 489 DSQSS 493
DS+SS
Sbjct: 1821 DSESS 1825
Score = 29.3 bits (64), Expect = 8.6
Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Query: 381 EAQTP-QAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRP--TLPAAPA 427
+A+ P A + P P AP+ P P P T ++ PP P +P PA
Sbjct: 1679 QAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPA 1728
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 52.8 bits (125), Expect = 7e-07
Identities = 42/151 (27%), Positives = 57/151 (37%), Gaps = 19/151 (12%)
Query: 344 WEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPP-----AP 398
W ++ + +T S + +P +T T P T PSPP P
Sbjct: 1390 WPMDKCITTPSPPTTTPSPPPTSTTTLPP-TTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448
Query: 399 SSTPTPTAPIATLNQPPPLLRP----TLPAAPALHRQPPPLQQQARFIQPRPTLNQPPP- 453
T TP+ PI+T PPP P T P+ P PP P PT PP
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT----PPPTTTPSPPT 1504
Query: 454 --PLIRPAN--SMPPRLNPRPVLSTVGGQQP 480
P+ PA+ ++PP P P +T P
Sbjct: 1505 TTPITPPASTTTLPPTTTPSPPTTTTTTPPP 1535
Score = 43.9 bits (102), Expect = 3e-04
Identities = 33/114 (28%), Positives = 41/114 (35%), Gaps = 16/114 (14%)
Query: 375 STDEEEEAQTPQAPRTLGPSPP-----APSSTPTPTAPIATLNQPPPLLRPTLPAA---- 425
ST TP P T +PP +P +T TP+ P T PPP P+ P
Sbjct: 1552 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611
Query: 426 --PALHRQPP---PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLST 474
P PP P+ PT PPP + PP P P +T
Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP--TTTTTPPPTTTPSPPTTT 1663
Score = 43.1 bits (100), Expect = 6e-04
Identities = 36/132 (27%), Positives = 48/132 (36%), Gaps = 17/132 (12%)
Query: 366 SASNVPSGKSTDEEEEAQTPQAPRTLGPSPPA-----PSSTPTP-----TAPIATLNQPP 415
+ + P +T + T P T PSPP P++TP+P T P T P
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502
Query: 416 PLLRPTLPAAPALHRQP--PPLQQQARFIQPRPTLNQPPP---PLIRPAN--SMPPRLNP 468
P P P A P P P PT PP P+ P + ++PP P
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562
Query: 469 RPVLSTVGGQQP 480
P +T P
Sbjct: 1563 SPPPTTTTTPPP 1574
Score = 42.4 bits (98), Expect = 0.001
Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 16/109 (14%)
Query: 382 AQTPQAPRTLGPSPPAPSST-PTPT---APIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 437
A T P T PSPP ++T P PT +P T PP TLP P PPP
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLP--PTTTPSPPPTTT 1569
Query: 438 QARFIQPRPTLNQPPPPLIRPA------NSMPPRLNPRPVLSTVGGQQP 480
P PT PP P+ + PP P P +T P
Sbjct: 1570 TT----PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPP 1614
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/116 (29%), Positives = 41/116 (35%), Gaps = 17/116 (14%)
Query: 375 STDEEEEAQTPQAPRTLGPSPP-----APSSTPTPTAPIATLNQPPPLLRP-----TLPA 424
ST TP P T +PP +P +T TP+ PI T PPP P T P+
Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690
Query: 425 APALHRQPP-----PLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTV 475
P P P P T PPP S P P P +T+
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS--PTTTPSPPTTTM 1744
Score = 41.6 bits (96), Expect = 0.002
Identities = 34/110 (30%), Positives = 38/110 (34%), Gaps = 12/110 (10%)
Query: 371 PSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHR 430
P +T T P T PSPP T T T P T PP P P P
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPP----TTTTTTPPPTTTPSPPTTTPITP--PTSTT 1633
Query: 431 QPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQP 480
PP + P PT PPP P S P P P ++T P
Sbjct: 1634 TLPPTTTPS----PPPTTTTTPPPTTTP--SPPTTTTPSPPITTTTTPPP 1677
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 14/115 (12%)
Query: 368 SNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPA 427
+ P +T T P T PSPP T TP P + PP P+ P P
Sbjct: 1593 TTTPPPTTTPSPPTTTTTTPPPTTTPSPP----TTTPITPPTSTTTLPPTTTPSPP--PT 1646
Query: 428 LHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 482
PPP P P P P I + PP P ++T PP+
Sbjct: 1647 TTTTPPPT------TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT--PSPPT 1693
Score = 35.0 bits (79), Expect = 0.16
Identities = 42/180 (23%), Positives = 56/180 (31%), Gaps = 17/180 (9%)
Query: 327 FFVNYRRRFNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQ 386
F +NY E + + T N T T + + P+ T + TP
Sbjct: 1865 FCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1924
Query: 387 APRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPR 445
T P P+ T TP T PI T P PT P P P
Sbjct: 1925 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---TTPITTTTTVTPTPT 1981
Query: 446 PTLNQPP-----------PPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGIQTDSQSSL 494
PT Q P P P + P P +TV P+ G QT + + +
Sbjct: 1982 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV--TPTPTPTGTQTPTTTPI 2039
Score = 34.3 bits (77), Expect = 0.27
Identities = 32/109 (29%), Positives = 41/109 (37%), Gaps = 11/109 (10%)
Query: 384 TPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPP---LQQQAR 440
TP +T +P ++T TPT PP T P A PPP Q +R
Sbjct: 4166 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSR 4225
Query: 441 F----IQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGG---QQPPS 482
+ TL PP I ++ PP P +T GG PPS
Sbjct: 4226 STSSPLTESTTLLSTLPPAIEMTSTAPPS-TPTAPTTTSGGHTLSPPPS 4273
Score = 34.3 bits (77), Expect = 0.27
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
Query: 388 PRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 437
P T P+P STPTP+ P +T ++P P +P P P PP Q+
Sbjct: 4377 PSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKP--PECPDF---DPPRQE 4421
Score = 33.9 bits (76), Expect = 0.35
Identities = 25/91 (27%), Positives = 32/91 (35%), Gaps = 8/91 (8%)
Query: 385 PQAPRTLGPSP-PAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQ 443
P + TL P+ P+P T T T P T PP P+ P PPP +
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT--TTPPPTTTPS---- 1682
Query: 444 PRPTLNQPPPPLIRPANSMPPRLNPRPVLST 474
P P PP P P+ +T
Sbjct: 1683 -SPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712
Score = 33.1 bits (74), Expect = 0.60
Identities = 32/131 (24%), Positives = 46/131 (35%), Gaps = 8/131 (6%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTP-TPTAPIATLNQPPPLLRPTL 422
T + + P+G T T +PP SSTP T + + L + LL
Sbjct: 4183 TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLP 4242
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPS 482
PA PP TL+ PP + PP R +T G P+
Sbjct: 4243 PAIEMTSTAPPSTPTAPTTTSGGHTLSPPP-----STTTSPPGTPTRG--TTTGSSSAPT 4295
Query: 483 LIGIQTDSQSS 493
+QT + S+
Sbjct: 4296 PSTVQTTTTSA 4306
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2017 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2076
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2077 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 2134 TTTV--TPTPTPTGTQTPTTTPI 2154
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2132 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2191
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2192 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 2249 TTTV--TPTPTPTGTQTPTTTPI 2269
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2247 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2306
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2307 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2363
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 2364 TTTV--TPTPTPTGTQTPTTTPI 2384
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2422 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 2479 TTTV--TPTPTPTGTQTPTTTPI 2499
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2536
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2537 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 2594 TTTV--TPTPTPTGTQTPTTTPI 2614
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2651
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2652 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 2709 TTTV--TPTPTPTGTQTPTTTPI 2729
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2766
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2767 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 2824 TTTV--TPTPTPTGTQTPTTTPI 2844
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2822 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2881
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2882 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 2939 TTTV--TPTPTPTGTQTPTTTPI 2959
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 2937 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2996
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 2997 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3054 TTTV--TPTPTPTGTQTPTTTPI 3074
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3111
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 3112 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3169 TTTV--TPTPTPTGTQTPTTTPI 3189
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3167 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3226
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 3227 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3284 TTTV--TPTPTPTGTQTPTTTPI 3304
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3341
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 3342 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3399 TTTV--TPTPTPTGTQTPTTTPI 3419
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3456
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 3457 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3514 TTTV--TPTPTPTGTQTPTTTPI 3534
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3512 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3571
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 3572 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3629 TTTV--TPTPTPTGTQTPTTTPI 3649
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3627 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3686
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 3687 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3744 TTTV--TPTPTPTGTQTPTTTPI 3764
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3742 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3801
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 3802 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3859 TTTV--TPTPTPTGTQTPTTTPI 3879
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3857 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3916
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 3917 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 3974 TTTV--TPTPTPTGTQTPTTTPI 3994
Score = 32.0 bits (71), Expect = 1.3
Identities = 35/143 (24%), Positives = 46/143 (32%), Gaps = 17/143 (11%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 3972 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4031
Query: 423 PAAPALHRQPPPLQQQARFIQPRPTLNQPP-----------PPLIRPANSMPPRLNPRPV 471
P P P PT Q P P P + P P
Sbjct: 4032 TQTPT---TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4088
Query: 472 LSTVGGQQPPSLIGIQTDSQSSL 494
+TV P+ G QT + + +
Sbjct: 4089 TTTV--TPTPTPTGTQTPTTTPI 4109
Score = 32.0 bits (71), Expect = 1.3
Identities = 33/142 (23%), Positives = 42/142 (29%), Gaps = 12/142 (8%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTP-TAPIATLNQPPPLLRPTL 422
T + + P+ T + TP T P P+ T TP T PI T P PT
Sbjct: 4087 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4146
Query: 423 PAAP---------ALHRQPPPLQQQARFIQPRPTLN--QPPPPLIRPANSMPPRLNPRPV 471
P + P P Q P T P P P + P+
Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPI 4206
Query: 472 LSTVGGQQPPSLIGIQTDSQSS 493
PP QT +S
Sbjct: 4207 AELTTSNPPPESSTPQTSRSTS 4228
Score = 30.0 bits (66), Expect = 5.0
Identities = 23/73 (31%), Positives = 27/73 (36%), Gaps = 7/73 (9%)
Query: 351 QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAP------RTLGPSPPAPSSTP-T 403
Q S +S L E T S +P TP AP TL P P +S P T
Sbjct: 4222 QTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGT 4281
Query: 404 PTAPIATLNQPPP 416
PT T + P
Sbjct: 4282 PTRGTTTGSSSAP 4294
Score = 29.3 bits (64), Expect = 8.6
Identities = 28/100 (28%), Positives = 32/100 (32%), Gaps = 25/100 (25%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLP 423
T S + PS T TP + T P PP +TP+PT T PP TLP
Sbjct: 1698 TPSPTTTPSSPITT----TTTPSSTTTPSP-PPTTMTTPSPT----TTPSPPTTTMTTLP 1748
Query: 424 AAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMP 463
P P PP I P P
Sbjct: 1749 PTTT----------------SSPLTTTPLPPSITPPTFSP 1772
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 52.0 bits (123), Expect = 1e-06
Identities = 75/303 (24%), Positives = 110/303 (36%), Gaps = 65/303 (21%)
Query: 218 PKGMYLTQEDVVAVSCSPNAANTIL--RQLDMELISLKRQVQNAKQVNSALKQKMEGGIE 275
P+ L +E + + N A+ R L +E+ L Q+ + +V +
Sbjct: 419 PQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKS---------- 468
Query: 276 EFKPPESNQKINARWTTEEQLLAVQGVRKYGKDF-QAIADVIGNKTVGQVKNFFVNYRRR 334
E K E +K+++ T +L ++K DF Q + D+ G K + +
Sbjct: 469 EAKAAELEKKLDSELTARHELQVE--MKKMESDFEQKLQDLQGEKDA--------LHSEK 518
Query: 335 FNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKST-------DEEEEAQTPQA 387
+ Q+ EAE G+ + L +E + A + S A P A
Sbjct: 519 QQIATEKQDLEAE--VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 576
Query: 388 PR------TLGPSPPAPSSTPTPTAPIATLNQPPPL-------LRPTLPAAPALHRQPPP 434
P T+ P PPAP + TP P PPPL P+LP A+ PPP
Sbjct: 577 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI-SPPPP 635
Query: 435 LQQQARFIQPRP----------------TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQ 478
L A P P T PPPPL A PP P P+ + G
Sbjct: 636 LSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP---PPPLPGSAGIP 692
Query: 479 QPP 481
PP
Sbjct: 693 PPP 695
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 21/112 (18%)
Query: 385 PQAPRTLGPSPPAPSSTPTPTA-------PIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 437
P P G P+PSS P TA P + PPP P LP + + PPPL
Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP---PPLPGSAGIPPPPPPLPG 700
Query: 438 QARFIQPRPTL----NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 485
+A P P L PPPP +PP P P + G PP G
Sbjct: 701 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGM----GMPPPPPFG 745
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 52.0 bits (123), Expect = 1e-06
Identities = 75/303 (24%), Positives = 110/303 (36%), Gaps = 65/303 (21%)
Query: 218 PKGMYLTQEDVVAVSCSPNAANTIL--RQLDMELISLKRQVQNAKQVNSALKQKMEGGIE 275
P+ L +E + + N A+ R L +E+ L Q+ + +V +
Sbjct: 428 PQYYKLIEECISQIVLHKNGADPDFKCRHLQIEIEGLIDQMIDKTKVEKS---------- 477
Query: 276 EFKPPESNQKINARWTTEEQLLAVQGVRKYGKDF-QAIADVIGNKTVGQVKNFFVNYRRR 334
E K E +K+++ T +L ++K DF Q + D+ G K + +
Sbjct: 478 EAKAAELEKKLDSELTARHELQVE--MKKMESDFEQKLQDLQGEKDA--------LHSEK 527
Query: 335 FNLEEVLQEWEAEQGTQASNGDASTLGEETKSASNVPSGKST-------DEEEEAQTPQA 387
+ Q+ EAE G+ + L +E + A + S A P A
Sbjct: 528 QQIATEKQDLEAE--VSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRAPVPPA 585
Query: 388 PR------TLGPSPPAPSSTPTPTAPIATLNQPPPL-------LRPTLPAAPALHRQPPP 434
P T+ P PPAP + TP P PPPL P+LP A+ PPP
Sbjct: 586 PPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAI-SPPPP 644
Query: 435 LQQQARFIQPRP----------------TLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQ 478
L A P P T PPPPL A PP P P+ + G
Sbjct: 645 LSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPP---PPPLPGSAGIP 701
Query: 479 QPP 481
PP
Sbjct: 702 PPP 704
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/112 (33%), Positives = 44/112 (39%), Gaps = 21/112 (18%)
Query: 385 PQAPRTLGPSPPAPSSTPTPTA-------PIATLNQPPPLLRPTLPAAPALHRQPPPLQQ 437
P P G P+PSS P TA P + PPP P LP + + PPPL
Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPP---PPLPGSAGIPPPPPPLPG 709
Query: 438 QARFIQPRPTL----NQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 485
+A P P L PPPP +PP P P + G PP G
Sbjct: 710 EAGMPPPPPPLPGGPGIPPPPPFPGGPGIPP---PPPGM----GMPPPPPFG 754
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 52.0 bits (123), Expect = 1e-06
Identities = 45/157 (28%), Positives = 65/157 (41%), Gaps = 19/157 (12%)
Query: 343 EWEAEQGTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSS-- 400
E E + + NG+ + S S PS + +E +P+ R PSPP
Sbjct: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET---SPRGRRRRSPSPPPTRRRR 559
Query: 401 TPTPTAPIATLNQPPPLLRPTLPAAPALHRQP------PPLQQQARFIQP--RPTLNQPP 452
+P+P P P P R P+ P R P PP+Q++ P R T + PP
Sbjct: 560 SPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619
Query: 453 PPLIRPANSMPPRLN------PRPVLSTVGGQQPPSL 483
PP R + S PP+ P+ S V ++ PSL
Sbjct: 620 PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656
Score = 31.6 bits (70), Expect = 1.7
Identities = 30/127 (23%), Positives = 49/127 (38%), Gaps = 11/127 (8%)
Query: 364 TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPP----APSS-----TPTP-TAPIATLNQ 413
++S S + + P+AP+T PP A SS +P+P T PI +++
Sbjct: 667 SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
Query: 414 PPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 473
P + A+P+ ++ P P +PP P P S P N P +
Sbjct: 727 TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP-PSPVQSQSPSTNWSPAVP 785
Query: 474 TVGGQQP 480
+ P
Sbjct: 786 VKKAKSP 792
Score = 31.2 bits (69), Expect = 2.3
Identities = 26/113 (23%), Positives = 38/113 (33%), Gaps = 5/113 (4%)
Query: 384 TPQAPRTLGPSPPAPS-STPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFI 442
+P R PSPP + P P + PP R + P R P ++++ +
Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656
Query: 443 QPRPTLNQPPPPLIRPANSMPPRL----NPRPVLSTVGGQQPPSLIGIQTDSQ 491
+ P R A S P +PRP PP G + Q
Sbjct: 657 SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQ 709
Score = 31.2 bits (69), Expect = 2.3
Identities = 27/110 (24%), Positives = 41/110 (37%), Gaps = 20/110 (18%)
Query: 385 PQAPRTLGPSPPAPS-STPTPTAPIATLNQPPPLLRPT------LPAAPALHRQ------ 431
P RT P PP ++P+P + PPP R + P+ + HR+
Sbjct: 609 PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR 668
Query: 432 -------PPPLQQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLST 474
P P ++ + +PR PP +R S P+ P ST
Sbjct: 669 STREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718
Score = 30.0 bits (66), Expect = 5.0
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 15/103 (14%)
Query: 381 EAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQAR 440
EA++PQ + PSP P AP T + PPP+ R ++P + P P + R
Sbjct: 672 EARSPQPNKRHSPSP-------RPRAP-QTSSSPPPVRRGA-SSSPQRRQSPSPSTRPIR 722
Query: 441 FIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS-TVGGQQPPS 482
+ P P I+ A S P+ R S +V G P+
Sbjct: 723 RVS-----RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 51.6 bits (122), Expect = 2e-06
Identities = 48/161 (29%), Positives = 60/161 (37%), Gaps = 25/161 (15%)
Query: 344 WEAEQG-----------TQASNGDASTLGEETKSASNVPSGKSTD-EEEEAQTPQAPRTL 391
W A QG T+ ++ K++ N+PS E + P
Sbjct: 818 WSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVP 877
Query: 392 GPSPPAPSSTPTPTAPIATLNQPPPL-----LRPTLPAAPALHRQPPPLQQQARF--IQP 444
P PP P T PT P + QPPPL L P P P PPP A + P
Sbjct: 878 PPPPPLPGMT-VPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPP 936
Query: 445 RPTLNQPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 485
P PPPP + P ++P P P L G PP L G
Sbjct: 937 LPGAGIPPPPPL-PGAAIP----PPPPLPGAGIPLPPPLPG 972
Score = 47.4 bits (111), Expect = 3e-05
Identities = 39/101 (38%), Positives = 43/101 (42%), Gaps = 14/101 (13%)
Query: 393 PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 448
P PP P + P P P A + PPPL +P P L R PPP I P P L
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Query: 449 N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 485
PPPPL P +P P P L VG PP L G
Sbjct: 1169 PGAGIPPPPPL--PGVGIP----PPPPLPGVGIPPPPPLPG 1203
Score = 46.2 bits (108), Expect = 7e-05
Identities = 38/102 (37%), Positives = 43/102 (42%), Gaps = 14/102 (13%)
Query: 393 PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 448
P PP P + P P P A + PPPL R +P P L PPP I P P L
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179
Query: 449 N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIGI 486
PPPPL P +P P P L G PP L G+
Sbjct: 1180 PGVGIPPPPPL--PGVGIP----PPPPLPGAGIPPPPPLPGM 1215
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/108 (35%), Positives = 43/108 (39%), Gaps = 17/108 (15%)
Query: 393 PSPPAPSST--PTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 448
P PP P + P P P A + PPPL +P P L PPP I P P L
Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003
Query: 449 N----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 485
PPPPL P +PP + P P L G PP L G
Sbjct: 1004 PGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049
Score = 43.9 bits (102), Expect = 3e-04
Identities = 39/114 (34%), Positives = 43/114 (37%), Gaps = 15/114 (13%)
Query: 385 PQAPRTLGPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFI 442
P A L P P P P P A + PPPL +P P L PPP I
Sbjct: 960 PGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1019
Query: 443 QPRPTLN----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 485
P P L PPPPL P +PP + P P L G PP L G
Sbjct: 1020 PPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1071
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/101 (36%), Positives = 41/101 (40%), Gaps = 14/101 (13%)
Query: 393 PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPRPTL 448
P PP P + P P P A + PPPL +P P L PPP I P P L
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1102
Query: 449 N----QPPPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLIG 485
PPPPL P +P P P L G PP L G
Sbjct: 1103 PGVGIPPPPPL--PGAGIP----PPPPLPGAGIPPPPPLPG 1137
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/110 (35%), Positives = 42/110 (38%), Gaps = 19/110 (17%)
Query: 393 PSPPAPSS-----TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPR 445
P PP P + P P A I PPPL +P P L PPP I P
Sbjct: 1076 PPPPLPGAGIPPPPPLPGAGIP---PPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1132
Query: 446 PTLN----QPPPPLIRPANSMPPRL-----NPRPVLSTVGGQQPPSLIGI 486
P L PPPPL R PP L P P L G PP L G+
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1182
Score = 39.7 bits (91), Expect = 0.006
Identities = 39/111 (35%), Positives = 43/111 (38%), Gaps = 23/111 (20%)
Query: 393 PSPPAPSS-----TPTPTAPIATLNQPPPLLRPTLPAAPALHRQ--PPPLQQQARFIQPR 445
P PP P + P P A I PPPL +P P L PPP I P
Sbjct: 1010 PPPPLPGAGIPPPPPLPGAGIP---PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1066
Query: 446 PTLN----QPPPPLIRPANSMPP-------RLNPRPVLSTVGGQQPPSLIG 485
P L PPPPL P +PP + P P L VG PP L G
Sbjct: 1067 PPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPG 1115
Score = 39.7 bits (91), Expect = 0.006
Identities = 27/71 (38%), Positives = 30/71 (42%), Gaps = 7/71 (9%)
Query: 393 PSPPAPSS--TPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQ 450
P PP P P P P A + PPPL +P APA PPL I P P L
Sbjct: 1186 PPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA-----PPLPPPGTGIPPPPLLPV 1240
Query: 451 PPPPLIRPANS 461
PPL+ S
Sbjct: 1241 SGPPLLPQVGS 1251
Score = 38.1 bits (87), Expect = 0.019
Identities = 38/112 (33%), Positives = 43/112 (38%), Gaps = 25/112 (22%)
Query: 385 PQAPRTLGPSPPA------PSSTPTPTAPIATLNQPPPLLR---PTLPAAPALHRQPPPL 435
P PR P PP P P P A I PPPL P P P + PPP
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIP---PPPPLPGVGIPPPPPLPGVGIPPPP- 1199
Query: 436 QQQARFIQPRPTLNQPPPPLIRPANSMPPRLNPRPVLSTVG-GQQPPSLIGI 486
P P PPPP + P +PP P P L G G PP L+ +
Sbjct: 1200 --------PLPGAGIPPPPPL-PGMGIPPA--PAPPLPPPGTGIPPPPLLPV 1240
Score = 37.7 bits (86), Expect = 0.024
Identities = 44/135 (32%), Positives = 49/135 (36%), Gaps = 38/135 (28%)
Query: 385 PQAPRTLG------PSPPAPSS-----TPTPTA--------PIATLNQPPPLLRPTLPAA 425
PQ P G P PP P + P P A P A + PPPL +P
Sbjct: 897 PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956
Query: 426 PALHRQ----PPPLQQQARFIQPRPTLN----QPPPPLIRPANSMPP-------RLNPRP 470
P L PPPL I P P L PPPPL P +PP + P P
Sbjct: 957 PPLPGAGIPLPPPLPGAG--IPPPPPLPGAGIPPPPPL--PGAGIPPPPPLPGAGIPPPP 1012
Query: 471 VLSTVGGQQPPSLIG 485
L G PP L G
Sbjct: 1013 PLPGAGIPPPPPLPG 1027
Score = 31.2 bits (69), Expect = 2.3
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 12/78 (15%)
Query: 347 EQGTQASNGDA--STLGEE--TKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTP 402
E+G + + DA + GEE + + P + EEEAQ GP PA +S P
Sbjct: 347 EEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQ--------GPDAPAAASLP 398
Query: 403 TPTAPIATLNQPPPLLRP 420
AP +P PL+ P
Sbjct: 399 GSPAPSQRCFKPYPLITP 416
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 51.6 bits (122), Expect = 2e-06
Identities = 39/130 (30%), Positives = 53/130 (40%), Gaps = 10/130 (7%)
Query: 360 LGEETKSASNVPSGKSTDEEE----EAQTPQAPRTLGPSPPAPSSTPTPTAPIATLNQPP 415
+G+ T ++ + G+ + E+ + + P AP T P TP A A P
Sbjct: 618 VGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAP 677
Query: 416 PLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLN-QPPPPLIRPANSMPPRLNPRPVLST 474
L P P P L PPP Q F P P PPPP PA ++PP P L
Sbjct: 678 TLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPP-----PPLPA 732
Query: 475 VGGQQPPSLI 484
G PP ++
Sbjct: 733 PPGVPPPPIL 742
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/135 (30%), Positives = 50/135 (37%), Gaps = 22/135 (16%)
Query: 347 EQGTQASNGDASTLGEETKSA--SNVPSGKSTDEEEEAQTPQAPRTLGPS---PPAPSST 401
++G Q+S D +E SA ++ K A AP L P+ PP P
Sbjct: 629 DEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFP 688
Query: 402 PTPTAPIATLNQP--------PPLLRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPP 453
P P P QP PP P PA PA+ PPPL + P P L PP
Sbjct: 689 PLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-VPPPPILPPLPP 747
Query: 454 PLIRPANSMPPRLNP 468
PP L P
Sbjct: 748 --------FPPGLFP 754
Score = 34.3 bits (77), Expect = 0.27
Identities = 46/189 (24%), Positives = 60/189 (31%), Gaps = 34/189 (17%)
Query: 338 EEVLQEWEAEQG-TQASNGDASTLGEETKSASNVPSGKSTDEEEE--------------A 382
EE +E AE+ A D GEE A P+ S EEE +
Sbjct: 1146 EEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPS 1205
Query: 383 QTPQAPRTLGPSPPAPSSTP--------------TPTAPIATLNQPPPLLRPTLPAAPAL 428
+ P +G PA S P +P P + PPL P
Sbjct: 1206 MLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLE 1265
Query: 429 HRQPPPLQQQARFIQPRPTLNQP----PPPLIRPANSMPPRLNPRPVLSTVGGQQPPSLI 484
PP+ P P P PPP ++ P + P P L+ P L
Sbjct: 1266 VEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP-LAEDHPPHTPGLC 1324
Query: 485 GIQTDSQSS 493
G SQS+
Sbjct: 1325 GSLAKSQST 1333
Score = 33.1 bits (74), Expect = 0.60
Identities = 32/129 (24%), Positives = 44/129 (34%), Gaps = 17/129 (13%)
Query: 371 PSGKSTDEEEEAQTPQAPRTLGPSPPA------PSSTP--TPTAPIATLNQPP-----PL 417
P+ EE + + L P PPA P +P P + +PP PL
Sbjct: 1219 PADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPL 1278
Query: 418 LRPTLPAAPALHRQPPPLQQQARF----IQPRPTLNQPPPPLIRPANSMPPRLNPRPVLS 473
P P P PPP + + P P PP S+ + V +
Sbjct: 1279 QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPA 1338
Query: 474 TVGGQQPPS 482
T GG+ P S
Sbjct: 1339 TPGGEPPLS 1347
Score = 30.8 bits (68), Expect = 3.0
Identities = 33/130 (25%), Positives = 40/130 (30%), Gaps = 19/130 (14%)
Query: 351 QASNGDASTLGEETKSASNVPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIAT 410
+A D++T A P+ QTP A P P PT TA
Sbjct: 369 KAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHF------PPPPEEPTATAAFGA 422
Query: 411 LNQ--------PPPL--LRPTLPAAPALHRQPPPLQQQARFIQPRPTLNQPPPPLIRPAN 460
+ PPPL P P PPP + + RPT P P P
Sbjct: 423 RDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGT 482
Query: 461 SMPPRLNPRP 470
P L P
Sbjct: 483 ---PTLESSP 489
Score = 30.8 bits (68), Expect = 3.0
Identities = 27/114 (23%), Positives = 40/114 (35%), Gaps = 21/114 (18%)
Query: 371 PSGKSTDEEEEAQTPQA------PRTLGPSPPAPSSTPTPTAPIATLNQPP--------P 416
P ++TD + P+ P T G S T T P +PP
Sbjct: 1295 PEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLS 1354
Query: 417 LLRPTLPAAPALHRQPPPL-------QQQARFIQPRPTLNQPPPPLIRPANSMP 463
L P +P +P + P P + R PT ++P PL+ P +P
Sbjct: 1355 LSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLP 1408
Score = 30.4 bits (67), Expect = 3.9
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 5/92 (5%)
Query: 370 VPSGKSTDEEEEAQTPQAPRTLGPSPPAPSSTPTPTAPIATLN---QPPPLLRPTLPAAP 426
+P+G+ + +P T G P P P P A A L + P L P LPA P
Sbjct: 1407 LPTGRRDERSGPLASPVLLET-GLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPA-P 1464
Query: 427 ALHRQPPPLQQQARFIQPRPTLNQPPPPLIRP 458
PP ++ R + P++ PL+RP
Sbjct: 1465 LASCPPPMKRKPGRPRRSPPSMLSLDGPLVRP 1496
>gi|112807226 hypothetical protein LOC91748 [Homo sapiens]
Length = 1045
Score = 51.6 bits (122), Expect = 2e-06
Identities = 39/155 (25%), Positives = 71/155 (45%), Gaps = 24/155 (15%)
Query: 1 MRVGAEYQARIPEFDPGATKYTDKDNGGMLVWSPYHSIPDAK-----LDEYIAIAKEK-- 53
+ VG+ +QA IP A D LVW P+ + ++ +++ + A
Sbjct: 723 INVGSRFQAEIPLMRDRALAAADPHKAD-LVWQPWEDLESSREKQRQVEDLLTAACSSIF 781
Query: 54 --HGYNVEQALGMLFWHKHNIEKSLADL-------PNFTPFP-------DEWTVEDKVLF 97
G N E AL L + +I ++L L P+ P D+W + ++ LF
Sbjct: 782 PGAGTNQELALHCLHESRGDILETLNKLLLKKPLRPHNHPLATYHYTGSDQWKMAERKLF 841
Query: 98 EQAFSFHGKSFHRIQQMLPDKTIASLVKYYYSWKK 132
+ + + K F +Q+++ KT+A V++YY++KK
Sbjct: 842 NKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKK 876
Score = 34.7 bits (78), Expect = 0.20
Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 23/114 (20%)
Query: 289 RWTTEEQLLAVQGVRKYGKDFQAIADVIGNKTVGQVKNFFVNYRRRFNLEEVLQEWEAEQ 348
+W E+ L +G+ Y KDF + +I KTV Q F+ Y+++ +
Sbjct: 832 QWKMAERKLFNKGIAIYKKDFFLVQKLIQTKTVAQCVEFYYTYKKQVKI--------GRN 883
Query: 349 GTQASNGDASTLGEETKSASNVPSGKSTDEEEEAQ---TPQAPRTLGPSPPAPS 399
GT + GD T E KS EE E + + PR P +PS
Sbjct: 884 GT-LTFGDVDTSDE-----------KSAQEEVEVDIKTSQKFPRVPLPRRESPS 925
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,164,594
Number of Sequences: 37866
Number of extensions: 1390069
Number of successful extensions: 18857
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 363
Number of HSP's successfully gapped in prelim test: 1226
Number of HSP's that attempted gapping in prelim test: 9569
Number of HSP's gapped (non-prelim): 6237
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.