Search of human proteins with 88942379

Search of human proteins with 88942379

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
         (395 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88942379 PREDICTED: PRAME family member [Homo sapiens]             814   0.0  
gi|59958373 PRAME family member 4 [Homo sapiens]                      765   0.0  
gi|148356236 PRAME family member 15 [Homo sapiens]                    764   0.0  
gi|61102721 PRAME family member 9 [Homo sapiens]                      764   0.0  
gi|61696142 PRAME family member 5 [Homo sapiens]                      756   0.0  
gi|58219004 PRAME family member 6 [Homo sapiens]                      756   0.0  
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]         753   0.0  
gi|226437621 PRAME family member 11 [Homo sapiens]                    748   0.0  
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]         748   0.0  
gi|153792112 PRAME family member 20 [Homo sapiens]                    630   0.0  
gi|153945800 PRAME family member 21 [Homo sapiens]                    630   0.0  
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]    566   e-161
gi|124249372 PRAME family member 12 [Homo sapiens]                    448   e-126
gi|239741053 PREDICTED: similar to Putative PRAME family member ...   436   e-122
gi|59676593 PRAME family member 7 [Homo sapiens]                      434   e-122
gi|59676587 PRAME family member 8 [Homo sapiens]                      434   e-122
gi|46249373 preferentially expressed antigen in melanoma [Homo s...   338   4e-93
gi|46249371 preferentially expressed antigen in melanoma [Homo s...   338   4e-93
gi|46249369 preferentially expressed antigen in melanoma [Homo s...   338   4e-93
gi|46249367 preferentially expressed antigen in melanoma [Homo s...   338   4e-93
gi|5174641 preferentially expressed antigen in melanoma [Homo sa...   338   4e-93
gi|154800493 PRAME family member 22 [Homo sapiens]                    310   2e-84
gi|153791443 PRAME family member 18 [Homo sapiens]                    305   4e-83
gi|113865933 PRAME family member 16 [Homo sapiens]                    304   8e-83
gi|194306638 PRAME family member 3 [Homo sapiens]                     303   1e-82
gi|12738831 PRAME family member 1 [Homo sapiens]                      303   2e-82
gi|66954681 PRAME family member 13 [Homo sapiens]                     303   2e-82
gi|157426839 PRAME family member 17 [Homo sapiens]                    302   4e-82
gi|194306635 PRAME family member 19 [Homo sapiens]                    302   4e-82
gi|194018546 PRAME family member 10 [Homo sapiens]                    301   5e-82

>gi|88942379 PREDICTED: PRAME family member [Homo sapiens]
          Length = 395

 Score =  814 bits (2102), Expect = 0.0
 Identities = 395/395 (100%), Positives = 395/395 (100%)

Query: 1   MSETGTRISPLFSHRRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRM 60
           MSETGTRISPLFSHRRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRM
Sbjct: 1   MSETGTRISPLFSHRRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRM 60

Query: 61  RGRQPLTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKM 120
           RGRQPLTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKM
Sbjct: 61  RGRQPLTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKM 120

Query: 121 VNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFT 180
           VNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFT
Sbjct: 121 VNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFT 180

Query: 181 TQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSIS 240
           TQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSIS
Sbjct: 181 TQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSIS 240

Query: 241 QLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELN 300
           QLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELN
Sbjct: 241 QLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELN 300

Query: 301 TFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKR 360
           TFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKR
Sbjct: 301 TFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKR 360

Query: 361 VRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 395
           VRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC
Sbjct: 361 VRDLRHPKRILFGTDYCPDCGNRSFYDLEADQYCC 395


>gi|59958373 PRAME family member 4 [Homo sapiens]
          Length = 478

 Score =  765 bits (1975), Expect = 0.0
 Identities = 370/381 (97%), Positives = 374/381 (98%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNKKPV+DCPRMRGRQPLTVFVELWL
Sbjct: 98  RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWL 157

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+LTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 158 KNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 217

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           WVLPILTQFTPYLGHMRNLQKL+LSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 218 WVLPILTQFTPYLGHMRNLQKLILSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 277

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQLLSCLKTSLK LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 278 NSVSFLEGHLDQLLSCLKTSLKFLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 337

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 338 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 397

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLLSHTIILKNLC+ELYPAPRESYGADGTLCWSRF QIRAELM RVRDLRHPKRILF T
Sbjct: 398 ENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCT 457

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           DYCPDCGNRSFYDLEADQYCC
Sbjct: 458 DYCPDCGNRSFYDLEADQYCC 478


>gi|148356236 PRAME family member 15 [Homo sapiens]
          Length = 478

 Score =  764 bits (1973), Expect = 0.0
 Identities = 372/381 (97%), Positives = 374/381 (98%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL
Sbjct: 98  RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 157

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+LT LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 158 KNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 217

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 218 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 277

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 278 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 337

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 338 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 397

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLLSHTIILKNLC+ELYPAPRESYGADGTLCWSRF QIRAELM RVRDLRHPKRILF T
Sbjct: 398 ENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCT 457

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           DYCPDCGNRSFYDLEADQYCC
Sbjct: 458 DYCPDCGNRSFYDLEADQYCC 478


>gi|61102721 PRAME family member 9 [Homo sapiens]
          Length = 478

 Score =  764 bits (1973), Expect = 0.0
 Identities = 372/381 (97%), Positives = 374/381 (98%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL
Sbjct: 98  RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 157

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+LT LLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 158 KNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 217

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 218 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 277

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 278 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 337

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 338 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 397

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLLSHTIILKNLC+ELYPAPRESYGADGTLCWSRF QIRAELM RVRDLRHPKRILF T
Sbjct: 398 ENLLSHTIILKNLCVELYPAPRESYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCT 457

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           DYCPDCGNRSFYDLEADQYCC
Sbjct: 458 DYCPDCGNRSFYDLEADQYCC 478


>gi|61696142 PRAME family member 5 [Homo sapiens]
          Length = 476

 Score =  756 bits (1953), Expect = 0.0
 Identities = 370/381 (97%), Positives = 373/381 (97%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNKKPVQDCPRMRG+QPLTVFVELWL
Sbjct: 96  RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+LTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 156 KNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 215

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL M
Sbjct: 216 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSM 275

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 276 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 335

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL
Sbjct: 336 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 395

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLLSHTIILKNLC+ELYPAPRESY ADGTLCWSRF QIRAELMKRVRDLRHPKRILF T
Sbjct: 396 ENLLSHTIILKNLCVELYPAPRESYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCT 455

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           D CPDCGNRSFYDLEADQ CC
Sbjct: 456 DCCPDCGNRSFYDLEADQCCC 476


>gi|58219004 PRAME family member 6 [Homo sapiens]
          Length = 476

 Score =  756 bits (1952), Expect = 0.0
 Identities = 370/381 (97%), Positives = 373/381 (97%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNK PVQDCPRMRG+QPLTVFVELWL
Sbjct: 96  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+LTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 156 KNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 215

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL M
Sbjct: 216 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSM 275

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 276 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 335

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL
Sbjct: 336 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 395

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLLSHTIILKNLC+ELYPAPRESY ADGTLCWSRF QIRAELMKRVRDLRHPKRILF T
Sbjct: 396 ENLLSHTIILKNLCVELYPAPRESYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCT 455

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           D CPDCGNRSFYDLEADQ CC
Sbjct: 456 DCCPDCGNRSFYDLEADQCCC 476


>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
          Length = 476

 Score =  753 bits (1944), Expect = 0.0
 Identities = 369/381 (96%), Positives = 372/381 (97%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNKKPVQDCPRMRG+QPLTVFVELWL
Sbjct: 96  RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+LTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 156 KNRTLDEYLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 215

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKL M
Sbjct: 216 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLCCLQKLSM 275

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 276 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 335

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALS CFELNTFSFCGNPISMATL
Sbjct: 336 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATL 395

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLLSHTIILKNLC+ELYPAPRESY ADGTLCWSRF QIRAELMKRVRDLRHPKRILF T
Sbjct: 396 ENLLSHTIILKNLCVELYPAPRESYDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCT 455

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           D CPDCGNRSFYDLEADQ CC
Sbjct: 456 DCCPDCGNRSFYDLEADQCCC 476


>gi|226437621 PRAME family member 11 [Homo sapiens]
          Length = 436

 Score =  748 bits (1931), Expect = 0.0
 Identities = 364/381 (95%), Positives = 371/381 (97%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNK PVQDCPRMR RQPLTVFVELWL
Sbjct: 56  RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWL 115

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+LTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 116 KNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 175

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           W+LPILTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 176 WILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 235

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 236 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 295

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 296 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 355

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLLSHTIILKNLCLELYPAP+ESYGADGTLCWSRF QIRAELMK+VR LRHPKRILF T
Sbjct: 356 ENLLSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCT 415

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           D CPD G+RSFYDLEADQYCC
Sbjct: 416 DNCPDHGDRSFYDLEADQYCC 436


>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
          Length = 513

 Score =  748 bits (1931), Expect = 0.0
 Identities = 364/381 (95%), Positives = 371/381 (97%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDVCENFWMVWSEAMA GCFLNAKRNK PVQDCPRMR RQPLTVFVELWL
Sbjct: 133 RRWKLQVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWL 192

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+LTCLLLWVKQR+DLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK
Sbjct: 193 KNRTLDEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 252

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           W+LPILTQFTPYLGH+RNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKL CLQKLYM
Sbjct: 253 WILPILTQFTPYLGHLRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLRCLQKLYM 312

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN
Sbjct: 313 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 372

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPI MATL
Sbjct: 373 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATL 432

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLLSHTIILKNLCLELYPAP+ESYGADGTLCWSRF QIRAELMK+VR LRHPKRILF T
Sbjct: 433 ENLLSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCT 492

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           D CPD G+RSFYDLEADQYCC
Sbjct: 493 DNCPDHGDRSFYDLEADQYCC 513


>gi|153792112 PRAME family member 20 [Homo sapiens]
          Length = 475

 Score =  630 bits (1626), Expect = 0.0
 Identities = 309/381 (81%), Positives = 333/381 (87%), Gaps = 1/381 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDV ENFWMVWSEAMAR C  NA  N+KPVQDCPRMRG+QPLTVF++L L
Sbjct: 96  RRWKLQVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+ TCL LWVKQR+ L+HLCCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC 
Sbjct: 156 KNRTLDEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCN 215

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           W LP+L +FTPYLG MRNL+KLVLS +D SRY+SPEQKKE VTQFTTQFLKL CLQKLYM
Sbjct: 216 WTLPVLAEFTPYLGQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYM 274

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQ+LSCLKTSL +L ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N
Sbjct: 275 NSVSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLAN 334

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           +SLVPLQ+LLEKVAATLEYLDLDDCGI+DSQVNAILPALSRCFEL TFSF GNPIS ATL
Sbjct: 335 FSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATL 394

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLL HTI L NLCLELYPAPRESY   G +C SRF Q+ AELM RVR LR P+RILF T
Sbjct: 395 ENLLCHTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCT 454

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           DYCP CGNRS YDLE D+ CC
Sbjct: 455 DYCPQCGNRSLYDLEVDRCCC 475


>gi|153945800 PRAME family member 21 [Homo sapiens]
          Length = 475

 Score =  630 bits (1626), Expect = 0.0
 Identities = 309/381 (81%), Positives = 333/381 (87%), Gaps = 1/381 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDLQDV ENFWMVWSEAMAR C  NA  N+KPVQDCPRMRG+QPLTVF++L L
Sbjct: 96  RRWKLQVLDLQDVSENFWMVWSEAMARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE+ TCL LWVKQR+ L+HLCCKKLK+LGM F NIR+ILK VNLDCIQEVEVNC 
Sbjct: 156 KNRTLDEYFTCLFLWVKQREGLVHLCCKKLKMLGMLFHNIRNILKTVNLDCIQEVEVNCN 215

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           W LP+L +FTPYLG MRNL+KLVLS +D SRY+SPEQKKE VTQFTTQFLKL CLQKLYM
Sbjct: 216 WTLPVLAEFTPYLGQMRNLRKLVLSDID-SRYISPEQKKEFVTQFTTQFLKLRCLQKLYM 274

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           NSVSFLEGHLDQ+LSCLKTSL +L ITNCVLLESDLKHLS+ PSI QLKTLDLSG RL N
Sbjct: 275 NSVSFLEGHLDQMLSCLKTSLNILAITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLAN 334

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           +SLVPLQ+LLEKVAATLEYLDLDDCGI+DSQVNAILPALSRCFEL TFSF GNPIS ATL
Sbjct: 335 FSLVPLQVLLEKVAATLEYLDLDDCGIVDSQVNAILPALSRCFELTTFSFRGNPISTATL 394

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLL HTI L NLCLELYPAPRESY   G +C SRF Q+ AELM RVR LR P+RILF T
Sbjct: 395 ENLLCHTIRLNNLCLELYPAPRESYDVRGIVCRSRFAQLGAELMGRVRALREPERILFCT 454

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
           DYCP CGNRS YDLE D+ CC
Sbjct: 455 DYCPQCGNRSLYDLEVDRCCC 475


>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
          Length = 474

 Score =  566 bits (1458), Expect = e-161
 Identities = 287/382 (75%), Positives = 316/382 (82%), Gaps = 4/382 (1%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RR KLQVL+L+DV ENFW +WS A    C   A   ++ V+DCPR   +QPL VF+++ L
Sbjct: 96  RRRKLQVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NC 133
           K + +DE L+    WV+ R+  +HLCC K+    M   N R+IL+ V  D IQ +E+ N 
Sbjct: 156 KEKFMDEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNM 215

Query: 134 KWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLY 193
            W   I+ +F+PYL  MRNL+KL +S  D  RY+     +E +  FTTQFLKLHCLQKLY
Sbjct: 216 CWPCMIV-EFSPYLSQMRNLRKLFIS--DGCRYLLSSDSQEQIAPFTTQFLKLHCLQKLY 272

Query: 194 MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT 253
           MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT
Sbjct: 273 MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT 332

Query: 254 NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT 313
           NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT
Sbjct: 333 NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT 392

Query: 314 LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG 373
           LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG
Sbjct: 393 LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG 452

Query: 374 TDYCPDCGNRSFYDLEADQYCC 395
           TDYCPDCGNRSFYDLEADQYCC
Sbjct: 453 TDYCPDCGNRSFYDLEADQYCC 474


>gi|124249372 PRAME family member 12 [Homo sapiens]
          Length = 483

 Score =  448 bits (1152), Expect = e-126
 Identities = 230/375 (61%), Positives = 277/375 (73%), Gaps = 2/375 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDL++V ENFW +WS A A      +KR  +   +CPR  G+QPL V ++L  
Sbjct: 96  RRWKLQVLDLRNVDENFWGIWSGASALSPEALSKR--RTAGNCPRPGGQQPLMVILDLCF 153

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KN  LDE LT  L W KQRK LLH+CCK+L+I G+    I  +L  V LDCIQEVEV C 
Sbjct: 154 KNGMLDECLTHFLEWGKQRKGLLHVCCKELQIFGIAIHRIIEVLNTVELDCIQEVEVCCP 213

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           W L IL +F PYLG MRNL+KLVL ++ VS  +  ++K++ V QFT+QFLKL   QKLYM
Sbjct: 214 WELSILIRFAPYLGQMRNLRKLVLFNIHVSACIPLDRKEQFVIQFTSQFLKLDYFQKLYM 273

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           +SVSFLEGHLDQLL CL+  L+ + +T C+L ESDLKHLS CPSI QLK LDL GI LT+
Sbjct: 274 HSVSFLEGHLDQLLRCLQAPLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTH 333

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           +S  PL +LLE+  ATL+ LDL+DCGI+DSQ++AILPALSRC +L+TFSFCGN ISMA L
Sbjct: 334 FSPEPLSVLLEQAEATLQTLDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAAL 393

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLL HT+ L  L LELYPAP ESY A G LCW RF+Q+ AELMK +RDLR PK I+F T
Sbjct: 394 ENLLRHTVGLSKLSLELYPAPLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFST 453

Query: 375 DYCPDCGNRSFYDLE 389
             CP CG R+ YDLE
Sbjct: 454 VPCPRCGIRASYDLE 468


>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
           [Homo sapiens]
          Length = 474

 Score =  436 bits (1120), Expect = e-122
 Identities = 225/381 (59%), Positives = 276/381 (72%), Gaps = 2/381 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           R+ KLQVLDL++V ENF  ++S A A   F  A   K+   +CP    +QP  VF++L L
Sbjct: 96  RQSKLQVLDLRNVDENFCDIFSGATAS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCL 153

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE LT LL W KQRK LLH+CCK+L++ GMP  +I  +L MV LDCIQEVEV C 
Sbjct: 154 KNRTLDECLTHLLEWGKQRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCP 213

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           W L  L +F PYLG MRNL+KLVL ++  S  + P+ K + + +FT+QFLKL   Q L M
Sbjct: 214 WELSTLVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSM 273

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           +SVSFLEGHLDQLL CL+ SL+++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT+
Sbjct: 274 HSVSFLEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTH 333

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           +S  PL  LLE+V ATL+ LDL+DCGI+DSQ++AILP LSRC +L+TFSFCGN ISMA L
Sbjct: 334 FSPEPLTGLLEQVVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAAL 393

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLL HT+ L  L LELYPAP ESY   G LCW RF ++ AELMK +RDLR PK I+F T
Sbjct: 394 ENLLRHTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCT 453

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
             CP CG R+ YDLE     C
Sbjct: 454 VPCPRCGIRASYDLEPSHCLC 474


>gi|59676593 PRAME family member 7 [Homo sapiens]
          Length = 474

 Score =  434 bits (1117), Expect = e-122
 Identities = 225/381 (59%), Positives = 275/381 (72%), Gaps = 2/381 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           R+ KLQVLDL++V ENF  ++S A A   F  A   K+   +CP    +QP  VF++L L
Sbjct: 96  RQSKLQVLDLRNVDENFCDIFSGATAS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCL 153

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE LT LL W KQRK LLH+CCK+L++ GMP  +I  +L MV LDCIQEVEV C 
Sbjct: 154 KNRTLDECLTHLLEWGKQRKGLLHVCCKELQVFGMPIHSIIEVLNMVELDCIQEVEVCCP 213

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           W L  L +F PYLG MRNL+KLVL ++  S  + P+ K + + +FT+QFLKL   Q L M
Sbjct: 214 WELSTLVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSM 273

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           +SVSFLEGHLDQLL CL+ SL+++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT+
Sbjct: 274 HSVSFLEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTH 333

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           +S  PL  LLE+V ATL+ LDL+DCGI+DSQ++AILP LSRC +L+TFSFCGN ISMA L
Sbjct: 334 FSPEPLTGLLEQVVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAAL 393

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLL HT+ L  L LELYPAP ESY   G LCW RF ++ AELMK  RDLR PK I+F T
Sbjct: 394 ENLLRHTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCT 453

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
             CP CG R+ YDLE     C
Sbjct: 454 VPCPRCGIRASYDLEPSHCLC 474


>gi|59676587 PRAME family member 8 [Homo sapiens]
          Length = 474

 Score =  434 bits (1116), Expect = e-122
 Identities = 224/381 (58%), Positives = 276/381 (72%), Gaps = 2/381 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           R+ KLQVLDL++V ENF  ++S A A   F  A   K+   +CP    +QP  VF++L L
Sbjct: 96  RQSKLQVLDLRNVDENFCDIFSGATAS--FPEALSQKQTADNCPGTGRQQPFMVFIDLCL 153

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           KNRTLDE LT LL W KQRK LLH+CC++L++ GMP  +I  +L MV LDCIQEVEV C 
Sbjct: 154 KNRTLDECLTHLLEWGKQRKGLLHVCCQELQVFGMPIHSIIEVLNMVELDCIQEVEVCCP 213

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYM 194
           W L  L +F PYLG MRNL+KLVL ++  S  + P+ K + + +FT+QFLKL   Q L M
Sbjct: 214 WELSTLVKFAPYLGQMRNLRKLVLFNIRASACIPPDNKGQFIARFTSQFLKLDYFQNLSM 273

Query: 195 NSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTN 254
           +SVSFLEGHLDQLL CL+ SL+++ +T+C+L ESDLKHLS CPSI QLK LDL G+ LT+
Sbjct: 274 HSVSFLEGHLDQLLRCLQASLEMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTH 333

Query: 255 YSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATL 314
           +S  PL  LLE+V ATL+ LDL+DCGI+DSQ++AILP LSRC +L+TFSFCGN ISMA L
Sbjct: 334 FSPEPLTGLLEQVVATLQTLDLEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAAL 393

Query: 315 ENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGT 374
           ENLL HT+ L  L LELYPAP ESY   G LCW RF ++ AELMK +RDLR PK I+F T
Sbjct: 394 ENLLRHTVGLSKLSLELYPAPLESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCT 453

Query: 375 DYCPDCGNRSFYDLEADQYCC 395
             CP CG R+ YDLE     C
Sbjct: 454 VPCPRCGIRASYDLEPSHCLC 474


>gi|46249373 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  338 bits (868), Expect = 4e-93
 Identities = 182/385 (47%), Positives = 248/385 (64%), Gaps = 10/385 (2%)

Query: 15  RRWKLQVLDLQ-DVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQ--------P 65
           RRWKLQVLDL+ +  ++FW VWS   A           +P+    ++ G          P
Sbjct: 115 RRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIP 174

Query: 66  LTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDC 125
           + V V+L+LK    DE  + L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD 
Sbjct: 175 VEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDS 234

Query: 126 IQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLK 185
           I+++EV C W LP L +F+PYLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL 
Sbjct: 235 IEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLS 294

Query: 186 LHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTL 245
           L CLQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L
Sbjct: 295 LQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVL 354

Query: 246 DLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFC 305
            LSG+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF 
Sbjct: 355 SLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFY 414

Query: 306 GNPISMATLENLLSHTIILKNLCLELYPAPRESY-GADGTLCWSRFTQIRAELMKRVRDL 364
           GN IS++ L++LL H I L NL   LYP P ESY    GTL   R   + A L + + +L
Sbjct: 415 GNSISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCEL 474

Query: 365 RHPKRILFGTDYCPDCGNRSFYDLE 389
             P  +    + CP CG+R+FYD E
Sbjct: 475 GRPSMVWLSANPCPHCGDRTFYDPE 499


>gi|46249371 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  338 bits (868), Expect = 4e-93
 Identities = 182/385 (47%), Positives = 248/385 (64%), Gaps = 10/385 (2%)

Query: 15  RRWKLQVLDLQ-DVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQ--------P 65
           RRWKLQVLDL+ +  ++FW VWS   A           +P+    ++ G          P
Sbjct: 115 RRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIP 174

Query: 66  LTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDC 125
           + V V+L+LK    DE  + L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD 
Sbjct: 175 VEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDS 234

Query: 126 IQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLK 185
           I+++EV C W LP L +F+PYLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL 
Sbjct: 235 IEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLS 294

Query: 186 LHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTL 245
           L CLQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L
Sbjct: 295 LQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVL 354

Query: 246 DLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFC 305
            LSG+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF 
Sbjct: 355 SLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFY 414

Query: 306 GNPISMATLENLLSHTIILKNLCLELYPAPRESY-GADGTLCWSRFTQIRAELMKRVRDL 364
           GN IS++ L++LL H I L NL   LYP P ESY    GTL   R   + A L + + +L
Sbjct: 415 GNSISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCEL 474

Query: 365 RHPKRILFGTDYCPDCGNRSFYDLE 389
             P  +    + CP CG+R+FYD E
Sbjct: 475 GRPSMVWLSANPCPHCGDRTFYDPE 499


>gi|46249369 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  338 bits (868), Expect = 4e-93
 Identities = 182/385 (47%), Positives = 248/385 (64%), Gaps = 10/385 (2%)

Query: 15  RRWKLQVLDLQ-DVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQ--------P 65
           RRWKLQVLDL+ +  ++FW VWS   A           +P+    ++ G          P
Sbjct: 115 RRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIP 174

Query: 66  LTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDC 125
           + V V+L+LK    DE  + L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD 
Sbjct: 175 VEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDS 234

Query: 126 IQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLK 185
           I+++EV C W LP L +F+PYLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL 
Sbjct: 235 IEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLS 294

Query: 186 LHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTL 245
           L CLQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L
Sbjct: 295 LQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVL 354

Query: 246 DLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFC 305
            LSG+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF 
Sbjct: 355 SLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFY 414

Query: 306 GNPISMATLENLLSHTIILKNLCLELYPAPRESY-GADGTLCWSRFTQIRAELMKRVRDL 364
           GN IS++ L++LL H I L NL   LYP P ESY    GTL   R   + A L + + +L
Sbjct: 415 GNSISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCEL 474

Query: 365 RHPKRILFGTDYCPDCGNRSFYDLE 389
             P  +    + CP CG+R+FYD E
Sbjct: 475 GRPSMVWLSANPCPHCGDRTFYDPE 499


>gi|46249367 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  338 bits (868), Expect = 4e-93
 Identities = 182/385 (47%), Positives = 248/385 (64%), Gaps = 10/385 (2%)

Query: 15  RRWKLQVLDLQ-DVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQ--------P 65
           RRWKLQVLDL+ +  ++FW VWS   A           +P+    ++ G          P
Sbjct: 115 RRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIP 174

Query: 66  LTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDC 125
           + V V+L+LK    DE  + L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD 
Sbjct: 175 VEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDS 234

Query: 126 IQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLK 185
           I+++EV C W LP L +F+PYLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL 
Sbjct: 235 IEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLS 294

Query: 186 LHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTL 245
           L CLQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L
Sbjct: 295 LQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVL 354

Query: 246 DLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFC 305
            LSG+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF 
Sbjct: 355 SLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFY 414

Query: 306 GNPISMATLENLLSHTIILKNLCLELYPAPRESY-GADGTLCWSRFTQIRAELMKRVRDL 364
           GN IS++ L++LL H I L NL   LYP P ESY    GTL   R   + A L + + +L
Sbjct: 415 GNSISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCEL 474

Query: 365 RHPKRILFGTDYCPDCGNRSFYDLE 389
             P  +    + CP CG+R+FYD E
Sbjct: 475 GRPSMVWLSANPCPHCGDRTFYDPE 499


>gi|5174641 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  338 bits (868), Expect = 4e-93
 Identities = 182/385 (47%), Positives = 248/385 (64%), Gaps = 10/385 (2%)

Query: 15  RRWKLQVLDLQ-DVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQ--------P 65
           RRWKLQVLDL+ +  ++FW VWS   A           +P+    ++ G          P
Sbjct: 115 RRWKLQVLDLRKNSHQDFWTVWSGNRASLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIP 174

Query: 66  LTVFVELWLKNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDC 125
           + V V+L+LK    DE  + L+  VK++K++L LCCKKLKI  MP ++I+ ILKMV LD 
Sbjct: 175 VEVLVDLFLKEGACDELFSYLIEKVKRKKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDS 234

Query: 126 IQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLK 185
           I+++EV C W LP L +F+PYLG M NL++L+LSH+  S Y+SPE++++ + QFT+QFL 
Sbjct: 235 IEDLEVTCTWKLPTLAKFSPYLGQMINLRRLLLSHIHASSYISPEKEEQYIAQFTSQFLS 294

Query: 186 LHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTL 245
           L CLQ LY++S+ FL G LDQLL  +   L+ L+ITNC L E D+ HLSQ PS+SQL  L
Sbjct: 295 LQCLQALYVDSLFFLRGRLDQLLRHVMNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVL 354

Query: 246 DLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFC 305
            LSG+ LT+ S  PLQ LLE+ +ATL+ L  D+CGI D Q+ A+LP+LS C +L T SF 
Sbjct: 355 SLSGVMLTDVSPEPLQALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFY 414

Query: 306 GNPISMATLENLLSHTIILKNLCLELYPAPRESY-GADGTLCWSRFTQIRAELMKRVRDL 364
           GN IS++ L++LL H I L NL   LYP P ESY    GTL   R   + A L + + +L
Sbjct: 415 GNSISISALQSLLQHLIGLSNLTHVLYPVPLESYEDIHGTLHLERLAYLHARLRELLCEL 474

Query: 365 RHPKRILFGTDYCPDCGNRSFYDLE 389
             P  +    + CP CG+R+FYD E
Sbjct: 475 GRPSMVWLSANPCPHCGDRTFYDPE 499


>gi|154800493 PRAME family member 22 [Homo sapiens]
          Length = 481

 Score =  310 bits (793), Expect = 2e-84
 Identities = 178/377 (47%), Positives = 237/377 (62%), Gaps = 5/377 (1%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVL+L+DV ENFW +WS A    C   A   ++ V+DCPR   +QPL VF+++ L
Sbjct: 98  RRWKLQVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCL 157

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NC 133
           K + +DE L+    WV+ R+  +HLCC K+    M   N R+IL+ V  D IQ +E+ N 
Sbjct: 158 KEKFMDEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNM 217

Query: 134 KWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLHCLQKL 192
            W   I+ +F+ YL  MRNL+KL +S  D  RY+ S + ++++V +F++  L+L  LQ L
Sbjct: 218 CWPCMIV-EFSRYLSQMRNLRKLFIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQML 274

Query: 193 YMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRL 252
           Y+  V F  GHLDQL+ CL++ L+ L +T   L + DLK L + PS+SQLK L+LS   L
Sbjct: 275 YVRRVCFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGAL 334

Query: 253 TNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMA 312
               L PL+ LLEKVAATL+ L L DCGI DS++  ILPALS C  L TF F GN  SM 
Sbjct: 335 RFIRLEPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMD 394

Query: 313 TLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILF 372
            L++LL HT  L NL LE YPAPRES    G +     T ++AELM+ +R++R PKRI F
Sbjct: 395 GLKDLLRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFF 454

Query: 373 GTDYCPDCGNRSFYDLE 389
           G   CP CG      LE
Sbjct: 455 GPVSCPCCGTSPTEQLE 471


>gi|153791443 PRAME family member 18 [Homo sapiens]
          Length = 479

 Score =  305 bits (782), Expect = 4e-83
 Identities = 177/377 (46%), Positives = 236/377 (62%), Gaps = 5/377 (1%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVL+++DV ENFW +WS A    C   A   ++ V+DCPR   +QPL VF+++ L
Sbjct: 96  RRWKLQVLEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NC 133
           K +++DE L+    WV+ R+  +HLCC K+    M   N R+IL+ V  D IQ +E+ N 
Sbjct: 156 KEKSVDEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNM 215

Query: 134 KWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLHCLQKL 192
            W   ++ + + YL  M+NL+KL +S  D   Y+ S E + ++V +F++ FL+L  LQ L
Sbjct: 216 CWPC-MVAEVSRYLSQMKNLRKLFIS--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQML 272

Query: 193 YMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRL 252
           YM  + F EG+LDQL+ CLK+ L+ L +T   L E DLK L   PS+SQLK L+LS   L
Sbjct: 273 YMRRIRFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTL 332

Query: 253 TNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMA 312
               L PL+ LLEKVAATL+ L L DCGI DS++  ILPALSRC  L TF F GN  SM 
Sbjct: 333 RFIRLEPLRALLEKVAATLQTLFLVDCGIGDSKLRVILPALSRCSNLTTFCFHGNDTSMD 392

Query: 313 TLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILF 372
            L++LL HT  L NL LE YPAPRES    G +     T ++AELM+ +R++R P RI F
Sbjct: 393 GLKDLLRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRIFF 452

Query: 373 GTDYCPDCGNRSFYDLE 389
           G   CP CG      LE
Sbjct: 453 GPVSCPCCGMSPTEQLE 469


>gi|113865933 PRAME family member 16 [Homo sapiens]
          Length = 474

 Score =  304 bits (779), Expect = 8e-83
 Identities = 175/369 (47%), Positives = 221/369 (59%), Gaps = 3/369 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDL+DV  NFW +WS A A  C   A R ++ V+D PR    QPL VF++L  
Sbjct: 96  RRWKLQVLDLRDVDGNFWTIWSGARALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQ 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           K  TLDE L+ L  W+  R+ L+HLCC K++   MP  + R++LK V  D IQE+E+  K
Sbjct: 156 KESTLDECLSYLCRWIHYRRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRK 215

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSH-MDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLY 193
             L    +F PYL  M NL+KL L+   D   YVS +Q  + V      FL L+  Q LY
Sbjct: 216 CSLNKTGKFAPYLSQMSNLRKLFLAFGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLY 273

Query: 194 MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT 253
           +  +S ++ HL+ LL CLK  L      +  L + D++ LSQ PS+SQLK L L  I + 
Sbjct: 274 IRKISNIKEHLEHLLRCLKNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMW 333

Query: 254 NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT 313
             +L PL  LLEKVAATLE L L DC I DSQ+  +LPALSRC +L TF F GN  S   
Sbjct: 334 TTNLEPLGALLEKVAATLEILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNA 393

Query: 314 LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG 373
           L++LL HT  L  L LELYPAP E     G + W     IRAELM  +R++R PKRI FG
Sbjct: 394 LKDLLCHTGGLSKLGLELYPAPLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFG 453

Query: 374 TDYCPDCGN 382
              CP CG+
Sbjct: 454 PIPCPSCGS 462


>gi|194306638 PRAME family member 3 [Homo sapiens]
          Length = 481

 Score =  303 bits (777), Expect = 1e-82
 Identities = 177/377 (46%), Positives = 235/377 (62%), Gaps = 5/377 (1%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RR KLQVL+L+DV ENFW +WS A    C   A   ++ V+DCPR   +QPL VF+++ L
Sbjct: 98  RRRKLQVLELRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCL 157

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NC 133
           K + +DE L+    WV+ R+  +HLCC K+    M   N R+IL+ V  D IQ +E+ N 
Sbjct: 158 KEKFMDEDLSFFSGWVQHRRGSVHLCCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNM 217

Query: 134 KWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLHCLQKL 192
            W   I+ +F  YL  MRNL+KL +S  D  RY+ S + ++++V +F++  L+L  LQ L
Sbjct: 218 CWPCMIV-EFIRYLSQMRNLRKLFIS--DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQML 274

Query: 193 YMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRL 252
           Y+  V F  GHLDQL+ CL++ L+ L +T   L + DLK L + PS+SQLK L+LS   L
Sbjct: 275 YVRRVCFFRGHLDQLIRCLRSPLETLALTYGFLEKVDLKCLPRYPSLSQLKQLNLSHGAL 334

Query: 253 TNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMA 312
               L PL+ LLEKVAATL+ L L DCGI DS++  ILPALS C  L TF F GN  SM 
Sbjct: 335 RFIRLEPLRALLEKVAATLQTLFLVDCGIRDSKLRVILPALSCCSNLTTFCFHGNDTSMD 394

Query: 313 TLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILF 372
            L++LL HT  L NL LE YPAPRES    G +     T ++AELM+ +R++R PKRI F
Sbjct: 395 GLKDLLRHTGRLSNLSLETYPAPRESLDDRGRVISELLTPLQAELMRILREVREPKRIFF 454

Query: 373 GTDYCPDCGNRSFYDLE 389
           G   CP CG      LE
Sbjct: 455 GPVSCPCCGTSPTEQLE 471


>gi|12738831 PRAME family member 1 [Homo sapiens]
          Length = 474

 Score =  303 bits (776), Expect = 2e-82
 Identities = 176/383 (45%), Positives = 234/383 (61%), Gaps = 6/383 (1%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDL+DV ENFW  W  A A  CF      ++  +DCPRM   QPL VF+++ L
Sbjct: 96  RRWKLQVLDLRDVDENFWARWPGAWALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NC 133
           K    DE L  L  WV QR+ L+HLCC KL     P + +R  LK++ L+ IQE+E+ N 
Sbjct: 156 KEIPQDECLRYLFQWVYQRRGLVHLCCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNM 215

Query: 134 KWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSP-EQKKEIVTQFTTQFLKLHCLQKL 192
            W   ++ +   YL  M+NL+KLV S      Y S  E +  +V +F++ FL+L  LQ L
Sbjct: 216 SWPR-LIRKLRCYLKEMKNLRKLVFSRCH--HYTSDNELQGRLVAKFSSVFLRLEHLQLL 272

Query: 193 YMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRL 252
            +  ++F  GHL+QL+ CL+  L+ L +T   LLE D+K LSQ PS+  LK L+LS + L
Sbjct: 273 KIKLITFFSGHLEQLIRCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLL 332

Query: 253 TNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMA 312
              SL PL  LLEK+AA+L+ L L+ C I  SQ++AILPALSRC +L TF F  N +S+ 
Sbjct: 333 FRISLEPLGALLEKIAASLKTLILEGCQIHYSQLSAILPALSRCSQLTTFYFGRNCMSID 392

Query: 313 TLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILF 372
            L++LL HT  L  L LE YPAP ES  +   + W  FT +RAELM  +R++R PKRI  
Sbjct: 393 ALKDLLRHTSGLSKLSLETYPAPEESLNSLVRVNWEIFTPLRAELMCTLREVRQPKRIFI 452

Query: 373 GTDYCPDCGNRSFYDLEADQYCC 395
           G   CP CG+    +LE    CC
Sbjct: 453 GPTPCPSCGSSPSEELEL-HLCC 474


>gi|66954681 PRAME family member 13 [Homo sapiens]
          Length = 474

 Score =  303 bits (775), Expect = 2e-82
 Identities = 174/382 (45%), Positives = 233/382 (60%), Gaps = 4/382 (1%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDL+DV ENFW  W  A A  CF      ++  +DCPRM   QPL VF+++ L
Sbjct: 96  RRWKLQVLDLRDVDENFWARWPGAWALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NC 133
           K    DE L  L  WV QR+ L+HLCC KL     P +++R  LK++ L+ IQ++E+ N 
Sbjct: 156 KEIPQDECLRYLFQWVYQRRGLVHLCCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNM 215

Query: 134 KWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLY 193
            W   ++ +   YL  M+NL+KLV S    S   + E +  +VT+F++ FL+L  LQ L 
Sbjct: 216 SWPR-LIRKLRCYLKEMKNLRKLVFSRCHHSMSDN-ELEGRLVTKFSSVFLRLEHLQLLK 273

Query: 194 MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT 253
           +  ++F  GHL+QL+ CL+  L+ L +T   LLE D+K LSQ PS+  LK L+LS + L 
Sbjct: 274 IKLITFFSGHLEQLIRCLQNPLENLELTYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLF 333

Query: 254 NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT 313
             SL PL  LLEK+AA+LE L L+ C I  SQ++AILP LS C +L TF F  N +SM  
Sbjct: 334 RISLEPLGALLEKIAASLETLILEGCQIHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGA 393

Query: 314 LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG 373
           L++LL HT  L  L LE YPAP ES  +   + W  F  +RAELM  +R++R PKRI  G
Sbjct: 394 LKDLLRHTSGLSKLSLETYPAPEESLNSLVRVDWEIFALLRAELMCTLREVRQPKRIFIG 453

Query: 374 TDYCPDCGNRSFYDLEADQYCC 395
              CP CG+    +LE    CC
Sbjct: 454 PTPCPSCGSSPSEELEL-HLCC 474


>gi|157426839 PRAME family member 17 [Homo sapiens]
          Length = 474

 Score =  302 bits (773), Expect = 4e-82
 Identities = 174/369 (47%), Positives = 220/369 (59%), Gaps = 3/369 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDL+DV  NFW +WS A A  C   A   ++ V+D PR    QPL VF++L  
Sbjct: 96  RRWKLQVLDLRDVDGNFWTIWSGARALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQ 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           K  TLDE L+ L  W+  R+ L+HLCC K++   MP  + R++LK V  D IQE+E+  K
Sbjct: 156 KESTLDECLSYLCRWIHYRRGLVHLCCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRK 215

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSH-MDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLY 193
             L    +F PYL  M NL+KL L+   D   YVS +Q  + V      FL L+  Q LY
Sbjct: 216 CSLNKTGKFAPYLSQMSNLRKLFLAFGYDDELYVSGQQ--QFVPDLDCPFLCLYYPQMLY 273

Query: 194 MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT 253
           +  +S ++ HL+ LL CLK  L      +  L + D++ LSQ PS+SQLK L L  I + 
Sbjct: 274 IRKISNIKEHLEHLLRCLKNPLGTFIFCHAYLADQDMECLSQYPSLSQLKELHLIHILMW 333

Query: 254 NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT 313
             +L PL  LLEKVAATLE L L DC I DSQ+  +LPALSRC +L TF F GN  S   
Sbjct: 334 TTNLEPLGALLEKVAATLEILTLKDCQIQDSQLRVLLPALSRCSQLTTFYFRGNETSTNA 393

Query: 314 LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG 373
           L++LL HT  L  L LELYPAP E     G + W     IRAELM  +R++R PKRI FG
Sbjct: 394 LKDLLCHTGGLSKLGLELYPAPLECLDNRGHVNWEILAPIRAELMCTLREVRQPKRIFFG 453

Query: 374 TDYCPDCGN 382
              CP CG+
Sbjct: 454 PIPCPSCGS 462


>gi|194306635 PRAME family member 19 [Homo sapiens]
          Length = 479

 Score =  302 bits (773), Expect = 4e-82
 Identities = 176/377 (46%), Positives = 235/377 (62%), Gaps = 5/377 (1%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVL+++DV ENFW +WS A    C   A   ++ V+DCPR   +QPL VF+++ L
Sbjct: 96  RRWKLQVLEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NC 133
           K +++DE L+    WV+ R+  +HLCC K+    M   N R+IL+ V  D IQ +E+ N 
Sbjct: 156 KEKSVDEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNM 215

Query: 134 KWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLHCLQKL 192
            W   ++ + + YL  M+NL+KL +S  D   Y+ S E + ++V +F++ FL+L  LQ L
Sbjct: 216 CWPC-MVAEVSRYLSQMKNLRKLFIS--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQML 272

Query: 193 YMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRL 252
           YM  + F EG+LDQL+ CLK+ L+ L +T   L E DLK L   PS+SQLK L+LS   L
Sbjct: 273 YMRRIRFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTL 332

Query: 253 TNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMA 312
               L PL+ LLEKVAATL+ L L DCGI  S++  ILPALSRC  L TF F GN  SM 
Sbjct: 333 RFIRLEPLRALLEKVAATLQTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMD 392

Query: 313 TLENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILF 372
            L++LL HT  L NL LE YPAPRES    G +     T ++AELM+ +R++R P RI F
Sbjct: 393 GLKDLLRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRIFF 452

Query: 373 GTDYCPDCGNRSFYDLE 389
           G   CP CG      LE
Sbjct: 453 GPVSCPCCGMSPTEQLE 469


>gi|194018546 PRAME family member 10 [Homo sapiens]
          Length = 474

 Score =  301 bits (772), Expect = 5e-82
 Identities = 171/369 (46%), Positives = 226/369 (61%), Gaps = 3/369 (0%)

Query: 15  RRWKLQVLDLQDVCENFWMVWSEAMARGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWL 74
           RRWKLQVLDL+DV ENFW +WS A    C   A   ++ V+DCPRM   QPL VF++L L
Sbjct: 96  RRWKLQVLDLRDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCL 155

Query: 75  KNRTLDEHLTCLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCK 134
           K  TLDE L+ L  W+  R+ L+HLCC K++   MP  + R++L+ +  D IQE+EV  K
Sbjct: 156 KESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKK 215

Query: 135 WVLPILTQFTPYLGHMRNLQKLVLSH-MDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLY 193
             L    +F PYL  M NL++L L+   +   YVS +     +    + FL L+  Q LY
Sbjct: 216 CSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWP--CIPDLDSPFLCLYYPQMLY 273

Query: 194 MNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLT 253
           +  +S ++ HL+ LL  LK  L     ++  L + D++ LSQ PS+SQLK L L  I + 
Sbjct: 274 IKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLTDRDMECLSQYPSLSQLKELRLIHILMW 333

Query: 254 NYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPISMAT 313
              L PL +LLEKVAATL+ L L DC I D Q+  +LPALS C +L TF+F GN  SM  
Sbjct: 334 TTHLEPLGVLLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNA 393

Query: 314 LENLLSHTIILKNLCLELYPAPRESYGADGTLCWSRFTQIRAELMKRVRDLRHPKRILFG 373
           L++LL HT  L  L LELYPAP ES    G + W   T IRAELM+ +R++R PKRI FG
Sbjct: 394 LKDLLRHTGGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFG 453

Query: 374 TDYCPDCGN 382
              CP+CG+
Sbjct: 454 PVPCPNCGS 462


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,051,476
Number of Sequences: 37866
Number of extensions: 643096
Number of successful extensions: 1870
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1760
Number of HSP's gapped (non-prelim): 89
length of query: 395
length of database: 18,247,518
effective HSP length: 104
effective length of query: 291
effective length of database: 14,309,454
effective search space: 4164051114
effective search space used: 4164051114
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.