Search of human proteins with 88900503

Search of human proteins with 88900503

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88900503 tyrosine hydroxylase isoform b [Homo sapiens]
         (497 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88900503 tyrosine hydroxylase isoform b [Homo sapiens]             993   0.0  
gi|88900505 tyrosine hydroxylase isoform c [Homo sapiens]             978   0.0  
gi|88900501 tyrosine hydroxylase isoform a [Homo sapiens]             977   0.0  
gi|4557819 phenylalanine hydroxylase [Homo sapiens]                   452   e-127
gi|31795563 tryptophan hydroxylase 2 [Homo sapiens]                   438   e-123
gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]                    434   e-122
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H...    35   0.12 
gi|18426913 drebrin 1 isoform b [Homo sapiens]                         35   0.16 
gi|18426915 drebrin 1 isoform a [Homo sapiens]                         35   0.16 
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap...    33   0.60 
gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]    33   0.60 
gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sap...    32   1.7  
gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sap...    32   1.7  
gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sap...    32   1.7  
gi|157266264 pleckstrin homology-like domain, family B, member 3...    32   1.7  
gi|148806891 hypothetical protein LOC54906 [Homo sapiens]              31   3.0  
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             30   5.1  
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...    29   8.7  
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...    29   8.7  
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...    29   8.7  
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...    29   8.7  
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...    29   8.7  

>gi|88900503 tyrosine hydroxylase isoform b [Homo sapiens]
          Length = 497

 Score =  993 bits (2567), Expect = 0.0
 Identities = 497/497 (100%), Positives = 497/497 (100%)

Query: 1   MPTPDATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAV 60
           MPTPDATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAV
Sbjct: 1   MPTPDATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAV 60

Query: 61  PSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQR 120
           PSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQR
Sbjct: 61  PSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQR 120

Query: 121 PRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSEDVRSPAGPKVPWFPRKVSELDKCHHLV 180
           PRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSEDVRSPAGPKVPWFPRKVSELDKCHHLV
Sbjct: 121 PRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSEDVRSPAGPKVPWFPRKVSELDKCHHLV 180

Query: 181 TKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLK 240
           TKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLK
Sbjct: 181 TKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLK 240

Query: 241 GLYATHACGEHLEAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFL 300
           GLYATHACGEHLEAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFL
Sbjct: 241 GLYATHACGEHLEAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFL 300

Query: 301 ASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASD 360
           ASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASD
Sbjct: 301 ASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASD 360

Query: 361 EEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQ 420
           EEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQ
Sbjct: 361 EEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQ 420

Query: 421 PYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLE 480
           PYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLE
Sbjct: 421 PYQDQTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLE 480

Query: 481 GVQDELDTLAHALSAIG 497
           GVQDELDTLAHALSAIG
Sbjct: 481 GVQDELDTLAHALSAIG 497


>gi|88900505 tyrosine hydroxylase isoform c [Homo sapiens]
          Length = 524

 Score =  978 bits (2529), Expect = 0.0
 Identities = 497/524 (94%), Positives = 497/524 (94%), Gaps = 27/524 (5%)

Query: 1   MPTPDATTPQAKGFRRAVSELDAKQAEAIM---------------------------SPR 33
           MPTPDATTPQAKGFRRAVSELDAKQAEAIM                           SPR
Sbjct: 1   MPTPDATTPQAKGFRRAVSELDAKQAEAIMGAPGPSLTGSPWPGTAAPAASYTPTPRSPR 60

Query: 34  FIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKP 93
           FIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKP
Sbjct: 61  FIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKP 120

Query: 94  SALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSE 153
           SALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSE
Sbjct: 121 SALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSE 180

Query: 154 DVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQY 213
           DVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQY
Sbjct: 181 DVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQY 240

Query: 214 RHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNIPQLE 273
           RHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNIPQLE
Sbjct: 241 RHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNIPQLE 300

Query: 274 DVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELL 333
           DVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELL
Sbjct: 301 DVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELL 360

Query: 334 GHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLL 393
           GHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLL
Sbjct: 361 GHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYGAGLL 420

Query: 394 SSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQR 453
           SSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQR
Sbjct: 421 SSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYASRIQR 480

Query: 454 PFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG 497
           PFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG
Sbjct: 481 PFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG 524


>gi|88900501 tyrosine hydroxylase isoform a [Homo sapiens]
          Length = 528

 Score =  977 bits (2525), Expect = 0.0
 Identities = 497/528 (94%), Positives = 497/528 (94%), Gaps = 31/528 (5%)

Query: 1   MPTPDATTPQAKGFRRAVSELDAKQAEAIM------------------------------ 30
           MPTPDATTPQAKGFRRAVSELDAKQAEAIM                              
Sbjct: 1   MPTPDATTPQAKGFRRAVSELDAKQAEAIMVRGQGAPGPSLTGSPWPGTAAPAASYTPTP 60

Query: 31  -SPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPR 89
            SPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPR
Sbjct: 61  RSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPR 120

Query: 90  ATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVR 149
           ATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVR
Sbjct: 121 ATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVR 180

Query: 150 QVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEI 209
           QVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEI
Sbjct: 181 QVSEDVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKLIAEI 240

Query: 210 AFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNI 269
           AFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNI
Sbjct: 241 AFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYREDNI 300

Query: 270 PQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCC 329
           PQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCC
Sbjct: 301 PQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCC 360

Query: 330 HELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYG 389
           HELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYG
Sbjct: 361 HELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEVKAYG 420

Query: 390 AGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYAS 449
           AGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYAS
Sbjct: 421 AGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLRSYAS 480

Query: 450 RIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG 497
           RIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG
Sbjct: 481 RIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALSAIG 528


>gi|4557819 phenylalanine hydroxylase [Homo sapiens]
          Length = 452

 Score =  452 bits (1163), Expect = e-127
 Identities = 224/423 (52%), Positives = 300/423 (70%), Gaps = 14/423 (3%)

Query: 82  LNLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDL 141
           ++L+FS +  +  AL++ +++FE  +  + H+E+RP++  +      E+F  L+ R   L
Sbjct: 35  ISLIFSLKE-EVGALAKVLRLFEENDVNLTHIESRPSRLKK---DEYEFFTHLDKR--SL 88

Query: 142 AALLSGVRQVSEDV--------RSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPG 193
            AL + ++ +  D+        R      VPWFPR + ELD+  + +  +  +LD DHPG
Sbjct: 89  PALTNIIKILRHDIGATVHELSRDKKKDTVPWFPRTIQELDRFANQILSYGAELDADHPG 148

Query: 194 FSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLE 253
           F D VYR RRK  A+IA+ YRHG PIPRVEY  EE  TW  V+ TLK LY THAC E+  
Sbjct: 149 FKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNH 208

Query: 254 AFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQY 313
            F LLE++ G+ EDNIPQLEDVS+FL+  TGF+LRPVAGLLS+RDFL  LAFRVF CTQY
Sbjct: 209 IFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQY 268

Query: 314 IRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFT 373
           IRH S PM++PEPD CHELLGHVP+ +DR+FAQFSQ+IGLASLGA DE IEKL+T+YWFT
Sbjct: 269 IRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFT 328

Query: 374 VEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFV 433
           VEFGLCKQ   +KAYGAGLLSS+GEL +CLSE+P++   + E  A+Q Y    +Q +Y+V
Sbjct: 329 VEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYV 388

Query: 434 SESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHAL 493
           +ESF+DAK+K+R++A+ I RPFSV++DPYT  I+VLD+ Q ++   + +  E+  L  AL
Sbjct: 389 AESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSAL 448

Query: 494 SAI 496
             I
Sbjct: 449 QKI 451


>gi|31795563 tryptophan hydroxylase 2 [Homo sapiens]
          Length = 490

 Score =  438 bits (1127), Expect = e-123
 Identities = 215/409 (52%), Positives = 290/409 (70%), Gaps = 13/409 (3%)

Query: 96  LSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVR-QVSED 154
           L +A+++F+     + H+E+R ++R  +    +E FV  E  + +   L+  ++ Q +  
Sbjct: 77  LVKALRLFQEKRVNMVHIESRKSRRRSS---EVEIFVDCECGKTEFNELIQLLKFQTTIV 133

Query: 155 VRSPAG---------PKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRKL 205
             +P             VPWFPRK+SELDKC H V  +  +LD DHPGF D VYRQRRK 
Sbjct: 134 TLNPPENIWTEEEELEDVPWFPRKISELDKCSHRVLMYGSELDADHPGFKDNVYRQRRKY 193

Query: 206 IAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHLEAFALLERFSGYR 265
             ++A  Y++G PIPRVEYT EE  TW  V+  L  LY THAC E+L+ F LL ++ GYR
Sbjct: 194 FVDVAMGYKYGQPIPRVEYTEEETKTWGVVFRELSKLYPTHACREYLKNFPLLTKYCGYR 253

Query: 266 EDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPE 325
           EDN+PQLEDVS FLKER+GF +RPVAG LS RDFLA LA+RVF CTQYIRH S P+++PE
Sbjct: 254 EDNVPQLEDVSMFLKERSGFTVRPVAGYLSPRDFLAGLAYRVFHCTQYIRHGSDPLYTPE 313

Query: 326 PDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGEV 385
           PD CHELLGHVP+LAD  FAQFSQ+IGLASLGASDE+++KL+T Y+FT+EFGLCKQ G++
Sbjct: 314 PDTCHELLGHVPLLADPKFAQFSQEIGLASLGASDEDVQKLATCYFFTIEFGLCKQEGQL 373

Query: 386 KAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSDAKDKLR 445
           +AYGAGLLSS GEL H LS++  ++AFDP+   +Q     T+Q  YFVSESF +AK+K+R
Sbjct: 374 RAYGAGLLSSIGELKHALSDKACVKAFDPKTTCLQECLITTFQEAYFVSESFEEAKEKMR 433

Query: 446 SYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHALS 494
            +A  I RPFSV F+PYT +I++L   +++   ++ ++ +L+T+  AL+
Sbjct: 434 DFAKSITRPFSVYFNPYTQSIEILKDTRSIENVVQDLRSDLNTVCDALN 482


>gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]
          Length = 444

 Score =  434 bits (1117), Expect = e-122
 Identities = 213/424 (50%), Positives = 293/424 (69%), Gaps = 14/424 (3%)

Query: 83  NLLFSPRATKPSALSRAVKVFETFEAKIHHLETRPAQRPRAGGPHLEYFVRLEVRR---G 139
           +L+FS +  +   L +A+K+F+     + H+E+R ++R  +     E FV  ++ R    
Sbjct: 19  SLIFSLK-NEVGGLIKALKIFQEKHVNLLHIESRKSKRRNS---EFEIFVDCDINREQLN 74

Query: 140 DLAALLSGVRQVSE-------DVRSPAGPKVPWFPRKVSELDKCHHLVTKFDPDLDLDHP 192
           D+  LL     V          ++      VPWFP+K+S+LD C + V  +  +LD DHP
Sbjct: 75  DIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHP 134

Query: 193 GFSDQVYRQRRKLIAEIAFQYRHGDPIPRVEYTAEEIATWKEVYTTLKGLYATHACGEHL 252
           GF D VYR+RRK  A++A  Y+HGDPIP+VE+T EEI TW  V+  L  LY THAC E+L
Sbjct: 135 GFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFQELNKLYPTHACREYL 194

Query: 253 EAFALLERFSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQ 312
           +   LL ++ GYREDNIPQLEDVS FLKERTGF +RPVAG LS RDFL+ LAFRVF CTQ
Sbjct: 195 KNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRDFLSGLAFRVFHCTQ 254

Query: 313 YIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWF 372
           Y+RH+S P ++PEPD CHELLGHVP+LA+ +FAQFSQ+IGLASLGAS+E ++KL+T Y+F
Sbjct: 255 YVRHSSDPFYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGASEEAVQKLATCYFF 314

Query: 373 TVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEIRAFDPEAAAVQPYQDQTYQSVYF 432
           TVEFGLCKQ+G+++ +GAGLLSS  EL H LS   +++ FDP+    Q     T+Q VYF
Sbjct: 315 TVEFGLCKQDGQLRVFGAGLLSSISELKHALSGHAKVKPFDPKITCKQECLITTFQDVYF 374

Query: 433 VSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAVRRSLEGVQDELDTLAHA 492
           VSESF DAK+K+R +   I+RPF VK++PYT +I +L   +++  ++  +Q +LD ++ A
Sbjct: 375 VSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSAMNELQHDLDVVSDA 434

Query: 493 LSAI 496
           L+ +
Sbjct: 435 LAKV 438


>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
           sapiens]
          Length = 785

 Score = 35.4 bits (80), Expect = 0.12
 Identities = 27/95 (28%), Positives = 42/95 (44%), Gaps = 16/95 (16%)

Query: 43  EDARKEREAAVAAAAAAVPSEP----------------GDPLEAVAFEEKEGKAVLNLLF 86
           E+A++ +EAA  + AA VP+EP                GD       +   G A+++LL 
Sbjct: 597 EEAKESKEAAQLSEAAPVPTEPQASQLLDLLDLLDGASGDVQHPPHLDPSPGGALVHLLD 656

Query: 87  SPRATKPSALSRAVKVFETFEAKIHHLETRPAQRP 121
            P    P A    +KVFE    +++    RP + P
Sbjct: 657 LPCVPPPPAPIPDLKVFEREGVQLNLSFIRPPENP 691


>gi|18426913 drebrin 1 isoform b [Homo sapiens]
          Length = 651

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 12/112 (10%)

Query: 6   ATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQ---SLIEDARKEREAAVAA------- 55
           A+TP A+   RA+ E+ + Q   +  P    +     S I D+ + R AA  A       
Sbjct: 346 ASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEE 405

Query: 56  --AAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFET 105
              A A P  PG P E + F E   +AVL     P     + +  A    ET
Sbjct: 406 PPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADTIET 457


>gi|18426915 drebrin 1 isoform a [Homo sapiens]
          Length = 649

 Score = 35.0 bits (79), Expect = 0.16
 Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 12/112 (10%)

Query: 6   ATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQ---SLIEDARKEREAAVAA------- 55
           A+TP A+   RA+ E+ + Q   +  P    +     S I D+ + R AA  A       
Sbjct: 344 ASTPVAEQIERALDEVTSSQPPPLPPPPPPAQETQEPSPILDSEETRAAAPQAWAGPMEE 403

Query: 56  --AAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFET 105
              A A P  PG P E + F E   +AVL     P     + +  A    ET
Sbjct: 404 PPQAQAPPRGPGSPAEDLMFMESAEQAVLAAPVEPATADATEIHDAADTIET 455


>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
           sapiens]
          Length = 431

 Score = 33.1 bits (74), Expect = 0.60
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 13/108 (12%)

Query: 47  KEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETF 106
           KE  A+  A    +       +E V F E++ KA+   L   RA +P+ L+      + +
Sbjct: 63  KETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLA------DVY 116

Query: 107 EAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSED 154
           +A++  L  R  Q             RLEV R +LA  L+ VRQ  +D
Sbjct: 117 QAELRELRLRLDQLTANSA-------RLEVERDNLAQDLATVRQKLQD 157


>gi|4503979 glial fibrillary acidic protein isoform 1 [Homo sapiens]
          Length = 432

 Score = 33.1 bits (74), Expect = 0.60
 Identities = 31/108 (28%), Positives = 48/108 (44%), Gaps = 13/108 (12%)

Query: 47  KEREAAVAAAAAAVPSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETF 106
           KE  A+  A    +       +E V F E++ KA+   L   RA +P+ L+      + +
Sbjct: 63  KETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLA------DVY 116

Query: 107 EAKIHHLETRPAQRPRAGGPHLEYFVRLEVRRGDLAALLSGVRQVSED 154
           +A++  L  R  Q             RLEV R +LA  L+ VRQ  +D
Sbjct: 117 QAELRELRLRLDQLTANSA-------RLEVERDNLAQDLATVRQKLQD 157


>gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
          Length = 1826

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 14/89 (15%)

Query: 2    PTPDATTPQAKGFRRAVSELDAKQAEAIM--SPRFIGRRQSLIEDARKEREAAVAAAAAA 59
            PTP A  P+       V+E  +K+A A    +P F+   QS             A++ ++
Sbjct: 1727 PTPIARAPRGSELSPMVAEPSSKEAAATFTEAPYFMASGQS------------PASSTSS 1774

Query: 60   VPSEPGDPLEAVAFEEKEGKAVLNLLFSP 88
             P+     L A AF +  GK V+++   P
Sbjct: 1775 APAATSQLLGAKAFAQLHGKPVISITSQP 1803


>gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
          Length = 1826

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 14/89 (15%)

Query: 2    PTPDATTPQAKGFRRAVSELDAKQAEAIM--SPRFIGRRQSLIEDARKEREAAVAAAAAA 59
            PTP A  P+       V+E  +K+A A    +P F+   QS             A++ ++
Sbjct: 1727 PTPIARAPRGSELSPMVAEPSSKEAAATFTEAPYFMASGQS------------PASSTSS 1774

Query: 60   VPSEPGDPLEAVAFEEKEGKAVLNLLFSP 88
             P+     L A AF +  GK V+++   P
Sbjct: 1775 APAATSQLLGAKAFAQLHGKPVISITSQP 1803


>gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
          Length = 1826

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 24/89 (26%), Positives = 39/89 (43%), Gaps = 14/89 (15%)

Query: 2    PTPDATTPQAKGFRRAVSELDAKQAEAIM--SPRFIGRRQSLIEDARKEREAAVAAAAAA 59
            PTP A  P+       V+E  +K+A A    +P F+   QS             A++ ++
Sbjct: 1727 PTPIARAPRGSELSPMVAEPSSKEAAATFTEAPYFMASGQS------------PASSTSS 1774

Query: 60   VPSEPGDPLEAVAFEEKEGKAVLNLLFSP 88
             P+     L A AF +  GK V+++   P
Sbjct: 1775 APAATSQLLGAKAFAQLHGKPVISITSQP 1803


>gi|157266264 pleckstrin homology-like domain, family B, member 3
           [Homo sapiens]
          Length = 640

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 21/80 (26%), Positives = 35/80 (43%)

Query: 3   TPDATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAVPS 62
           TP A+T   +G R A   L  +Q EA+     + +R   ++  RKE    +    A +  
Sbjct: 83  TPPASTSSREGVRGAARRLQGQQLEALTRVALMEQRVKELQRQRKELRIEMEVEVALLRG 142

Query: 63  EPGDPLEAVAFEEKEGKAVL 82
           E      A   EE++ + +L
Sbjct: 143 ELAGERVAARREEEQLRELL 162


>gi|148806891 hypothetical protein LOC54906 [Homo sapiens]
          Length = 2430

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 9/115 (7%)

Query: 220  PRVEYTAEEIATWKEV-YTTLKGLYATHACGEHLEAFALLERFSGYREDNI---PQLEDV 275
            PR E  A EI  ++E  ++ L+        GE  E  AL E       DN+   P + + 
Sbjct: 1294 PREEMPAGEIEQFEEAPFSNLELQDVAEEIGEP-EEVALTESREVSSADNVSVYPSVSEE 1352

Query: 276  SRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQY----IRHASSPMHSPEP 326
                KER G  L+PV  +LS  +    +A  +   + +    +    SP  SPEP
Sbjct: 1353 PVENKERKGDNLQPVTLILSKENCTLEIAEEINVTSDFPFDSVIEEVSPASSPEP 1407


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 44/166 (26%), Positives = 58/166 (34%), Gaps = 25/166 (15%)

Query: 1    MPTPDATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAV 60
            +PTP+  T  A        E  A  A A+ +P                 E A  AAA   
Sbjct: 1098 VPTPEEPTSPAAAV--PTPEEPASPAAAVPTPE----------------EPASPAAAVPT 1139

Query: 61   PSEPGDPLEAVAFEEKEGKAVLNLLFSPRATKPSALSRAVKVFETFEAKIHHLE--TRPA 118
            P EP  P  AV   E+   A + +     +  P+A         +F A +  LE  T PA
Sbjct: 1140 PEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPA 1199

Query: 119  ---QRPRAGGPHLEYFV--RLEVRRGDLAALLSGVRQVSEDVRSPA 159
                 P A    LE F      V   +  A L+      E+  SPA
Sbjct: 1200 ASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPA 1245


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
            isoform 1 [Homo sapiens]
          Length = 1599

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 9/80 (11%)

Query: 6    ATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPG 65
            A TP  K  R    E++ +  E    P  + +  SL ED  + R+A    AA      P 
Sbjct: 1177 ARTPATK--RSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL----PPV 1230

Query: 66   DPLEAVAFE---EKEGKAVL 82
             PL+A   E   EK+ KA++
Sbjct: 1231 SPLKAALSEEELEKKSKAII 1250


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
            isoform 2 [Homo sapiens]
          Length = 1512

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 9/80 (11%)

Query: 6    ATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPG 65
            A TP  K  R    E++ +  E    P  + +  SL ED  + R+A    AA      P 
Sbjct: 1090 ARTPATK--RSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL----PPV 1143

Query: 66   DPLEAVAFE---EKEGKAVL 82
             PL+A   E   EK+ KA++
Sbjct: 1144 SPLKAALSEEELEKKSKAII 1163


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
            isoform 3 [Homo sapiens]
          Length = 1435

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 9/80 (11%)

Query: 6    ATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPG 65
            A TP  K  R    E++ +  E    P  + +  SL ED  + R+A    AA      P 
Sbjct: 1013 ARTPATK--RSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL----PPV 1066

Query: 66   DPLEAVAFE---EKEGKAVL 82
             PL+A   E   EK+ KA++
Sbjct: 1067 SPLKAALSEEELEKKSKAII 1086


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
            isoform 1 [Homo sapiens]
          Length = 1599

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 9/80 (11%)

Query: 6    ATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPG 65
            A TP  K  R    E++ +  E    P  + +  SL ED  + R+A    AA      P 
Sbjct: 1177 ARTPATK--RSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL----PPV 1230

Query: 66   DPLEAVAFE---EKEGKAVL 82
             PL+A   E   EK+ KA++
Sbjct: 1231 SPLKAALSEEELEKKSKAII 1250


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
            isoform 4 [Homo sapiens]
          Length = 1403

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 9/80 (11%)

Query: 6    ATTPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAVAAAAAAVPSEPG 65
            A TP  K  R    E++ +  E    P  + +  SL ED  + R+A    AA      P 
Sbjct: 981  ARTPATK--RSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAAL----PPV 1034

Query: 66   DPLEAVAFE---EKEGKAVL 82
             PL+A   E   EK+ KA++
Sbjct: 1035 SPLKAALSEEELEKKSKAII 1054


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,412,104
Number of Sequences: 37866
Number of extensions: 897181
Number of successful extensions: 2632
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2600
Number of HSP's gapped (non-prelim): 41
length of query: 497
length of database: 18,247,518
effective HSP length: 106
effective length of query: 391
effective length of database: 14,233,722
effective search space: 5565385302
effective search space used: 5565385302
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.