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Search of human proteins with 88853069
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88853069 vitronectin precursor [Homo sapiens]
(478 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88853069 vitronectin precursor [Homo sapiens] 1015 0.0
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 124 2e-28
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 124 2e-28
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 124 2e-28
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 124 2e-28
gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens] 80 5e-15
gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein ... 79 7e-15
gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens] 79 7e-15
gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens] 77 4e-14
gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens] 69 9e-12
gi|58331148 matrix metalloproteinase 11 preproprotein [Homo sapi... 67 4e-11
gi|112382270 matrix metalloproteinase 17 preproprotein [Homo sap... 66 6e-11
gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprot... 63 5e-10
gi|11321561 hemopexin precursor [Homo sapiens] 62 1e-09
gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens] 60 3e-09
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 60 4e-09
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 60 4e-09
gi|11968059 matrix metalloproteinase 25 preproprotein [Homo sapi... 59 1e-08
gi|73858572 matrix metalloproteinase 12 preproprotein [Homo sapi... 58 2e-08
gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens] 57 4e-08
gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens] 55 1e-07
gi|22218341 matrix metalloproteinase 21 preproprotein [Homo sapi... 49 1e-05
gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein ... 48 2e-05
gi|73808268 matrix metalloproteinase 27 [Homo sapiens] 48 2e-05
gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens] 47 4e-05
gi|45359865 matrix metalloproteinase 20 preproprotein [Homo sapi... 47 4e-05
gi|5174623 placental protein 11 precursor [Homo sapiens] 45 2e-04
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] 42 0.002
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] 42 0.002
gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] 42 0.002
>gi|88853069 vitronectin precursor [Homo sapiens]
Length = 478
Score = 1015 bits (2624), Expect = 0.0
Identities = 478/478 (100%), Positives = 478/478 (100%)
Query: 1 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP 60
MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP
Sbjct: 1 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP 60
Query: 61 QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE 120
QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE
Sbjct: 61 QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE 120
Query: 121 EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC 180
EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC
Sbjct: 121 EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC 180
Query: 181 YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP 240
YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP
Sbjct: 181 YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP 240
Query: 241 RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA 300
RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA
Sbjct: 241 RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA 300
Query: 301 VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA 360
VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA
Sbjct: 301 VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA 360
Query: 361 PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY 420
PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY
Sbjct: 361 PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY 420
Query: 421 RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL 478
RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL
Sbjct: 421 RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL 478
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 124 bits (311), Expect = 2e-28
Identities = 86/249 (34%), Positives = 119/249 (47%), Gaps = 26/249 (10%)
Query: 69 TMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPE-V 127
TMP K +T+ E + S ++ Q+ P QTP K E P E
Sbjct: 905 TMPRVRKPKTTPTPRKMTSTMPE-LNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 963
Query: 128 GASKPE-----------------GIDSRPETLHPG---RPQPPAEEELCSGKPFDAFTDL 167
G ++ E +D P + G P E +C+GKP D T L
Sbjct: 964 GGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTL 1023
Query: 168 KNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQY 227
+NG+L AFRG Y + L + P + I +VWGI PID FTR NC+GKT+ FK SQY
Sbjct: 1024 RNGTLVAFRGHYFWMLSPFSP-PSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQY 1082
Query: 228 WRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFK-GKQYWEYQFQH 286
WRF + + D YP+ I GF G+ + AAL+ + + E VYFFK G +Y ++
Sbjct: 1083 WRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYK-NWPESVYFFKRGGSIQQYIYKQ 1141
Query: 287 QPSQEECEG 295
+P Q +C G
Sbjct: 1142 EPVQ-KCPG 1149
Score = 55.1 bits (131), Expect = 1e-07
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 3 PLRPLLILALLAWVALADQE-SCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAEC 58
P+ LL+L++ ++ QE SCKGRC E F ++C CD C Y CC DY + C
Sbjct: 7 PIYLLLLLSVFVIQQVSSQELSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 63
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 124 bits (311), Expect = 2e-28
Identities = 86/249 (34%), Positives = 119/249 (47%), Gaps = 26/249 (10%)
Query: 69 TMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPE-V 127
TMP K +T+ E + S ++ Q+ P QTP K E P E
Sbjct: 946 TMPRVRKPKTTPTPRKMTSTMPE-LNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1004
Query: 128 GASKPE-----------------GIDSRPETLHPG---RPQPPAEEELCSGKPFDAFTDL 167
G ++ E +D P + G P E +C+GKP D T L
Sbjct: 1005 GGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTL 1064
Query: 168 KNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQY 227
+NG+L AFRG Y + L + P + I +VWGI PID FTR NC+GKT+ FK SQY
Sbjct: 1065 RNGTLVAFRGHYFWMLSPFSP-PSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQY 1123
Query: 228 WRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFK-GKQYWEYQFQH 286
WRF + + D YP+ I GF G+ + AAL+ + + E VYFFK G +Y ++
Sbjct: 1124 WRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYK-NWPESVYFFKRGGSIQQYIYKQ 1182
Query: 287 QPSQEECEG 295
+P Q +C G
Sbjct: 1183 EPVQ-KCPG 1190
Score = 53.9 bits (128), Expect = 3e-07
Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
Query: 3 PLRPLLILAL--LAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP 60
P+ LL+L++ + V+ D SC GRC EG++ D C CD C +Y CC D+ C
Sbjct: 7 PIYLLLLLSVFVIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTA 66
Query: 61 QVT 63
+++
Sbjct: 67 ELS 69
Score = 49.7 bits (117), Expect = 6e-06
Identities = 18/36 (50%), Positives = 21/36 (58%)
Query: 23 SCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAEC 58
SCKGRC E F ++C CD C Y CC DY + C
Sbjct: 69 SCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 104
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 124 bits (311), Expect = 2e-28
Identities = 86/249 (34%), Positives = 119/249 (47%), Gaps = 26/249 (10%)
Query: 69 TMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPE-V 127
TMP K +T+ E + S ++ Q+ P QTP K E P E
Sbjct: 998 TMPRVRKPKTTPTPRKMTSTMPE-LNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1056
Query: 128 GASKPE-----------------GIDSRPETLHPG---RPQPPAEEELCSGKPFDAFTDL 167
G ++ E +D P + G P E +C+GKP D T L
Sbjct: 1057 GGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTL 1116
Query: 168 KNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQY 227
+NG+L AFRG Y + L + P + I +VWGI PID FTR NC+GKT+ FK SQY
Sbjct: 1117 RNGTLVAFRGHYFWMLSPFSP-PSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQY 1175
Query: 228 WRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFK-GKQYWEYQFQH 286
WRF + + D YP+ I GF G+ + AAL+ + + E VYFFK G +Y ++
Sbjct: 1176 WRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYK-NWPESVYFFKRGGSIQQYIYKQ 1234
Query: 287 QPSQEECEG 295
+P Q +C G
Sbjct: 1235 EPVQ-KCPG 1242
Score = 55.1 bits (131), Expect = 1e-07
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 3 PLRPLLILALLAWVALADQE-SCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAEC 58
P+ LL+L++ ++ QE SCKGRC E F ++C CD C Y CC DY + C
Sbjct: 7 PIYLLLLLSVFVIQQVSSQELSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 63
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 124 bits (311), Expect = 2e-28
Identities = 86/249 (34%), Positives = 119/249 (47%), Gaps = 26/249 (10%)
Query: 69 TMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPE-V 127
TMP K +T+ E + S ++ Q+ P QTP K E P E
Sbjct: 1039 TMPRVRKPKTTPTPRKMTSTMPE-LNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDA 1097
Query: 128 GASKPE-----------------GIDSRPETLHPG---RPQPPAEEELCSGKPFDAFTDL 167
G ++ E +D P + G P E +C+GKP D T L
Sbjct: 1098 GGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTL 1157
Query: 168 KNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQY 227
+NG+L AFRG Y + L + P + I +VWGI PID FTR NC+GKT+ FK SQY
Sbjct: 1158 RNGTLVAFRGHYFWMLSPFSP-PSPARRITEVWGIPSPIDTVFTRCNCEGKTFFFKDSQY 1216
Query: 228 WRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFK-GKQYWEYQFQH 286
WRF + + D YP+ I GF G+ + AAL+ + + E VYFFK G +Y ++
Sbjct: 1217 WRFTNDIKDAGYPKPIFKGFGGLTGQIVAALSTAKYK-NWPESVYFFKRGGSIQQYIYKQ 1275
Query: 287 QPSQEECEG 295
+P Q +C G
Sbjct: 1276 EPVQ-KCPG 1283
Score = 53.9 bits (128), Expect = 3e-07
Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
Query: 3 PLRPLLILAL--LAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP 60
P+ LL+L++ + V+ D SC GRC EG++ D C CD C +Y CC D+ C
Sbjct: 7 PIYLLLLLSVFVIQQVSSQDLSSCAGRCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTA 66
Query: 61 QVT 63
+++
Sbjct: 67 ELS 69
Score = 49.7 bits (117), Expect = 6e-06
Identities = 18/36 (50%), Positives = 21/36 (58%)
Query: 23 SCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAEC 58
SCKGRC E F ++C CD C Y CC DY + C
Sbjct: 69 SCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFC 104
>gi|4826834 matrix metalloproteinase 14 preproprotein [Homo sapiens]
Length = 582
Score = 79.7 bits (195), Expect = 5e-15
Identities = 63/222 (28%), Positives = 102/222 (45%), Gaps = 28/222 (12%)
Query: 137 SRPETLHPGRPQPPAE-EELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKL 195
SRP P +P+ P +C G FD L+ G +F F+ ++ + + V GYP
Sbjct: 301 SRPSV--PDKPKNPTYGPNICDGN-FDTVAMLR-GEMFVFKERWFWRVRNNQVMDGYPMP 356
Query: 196 IRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIP-DN 253
I W G+ I+ A+ R + GK FKG ++W F++ L+P YP++I + G+P D
Sbjct: 357 IGQFWRGLPASINTAYERKD--GKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDK 414
Query: 254 VDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSW 313
+DAAL + + YFF+G +Y Y+F + + E V+E R S+
Sbjct: 415 IDAAL-----FWMPNGKTYFFRGNKY--YRFNEELRAVDSEYPKNIKVWEGIPESPRGSF 467
Query: 314 ---EDIFELLFWG---------RTSAGTRQPQFISRDWHGVP 343
+++F + G + P+ RDW G P
Sbjct: 468 MGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCP 509
Score = 39.3 bits (90), Expect = 0.008
Identities = 15/40 (37%), Positives = 27/40 (67%), Gaps = 3/40 (7%)
Query: 437 FFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPG 476
+F+ G+KY++ N + +V+ P YP+S + W+GCP+ G
Sbjct: 476 YFYKGNKYWKFNNQKLKVE---PGYPKSALRDWMGCPSGG 512
Score = 34.3 bits (77), Expect = 0.26
Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 4/42 (9%)
Query: 432 PIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCP 473
P +FF G+KYYR N R VD+ YP++I + W G P
Sbjct: 423 PNGKTYFFRGNKYYRFNEELRAVDS---EYPKNI-KVWEGIP 460
>gi|13027802 matrix metalloproteinase 16 isoform 1 preproprotein
[Homo sapiens]
Length = 607
Score = 79.3 bits (194), Expect = 7e-15
Identities = 62/192 (32%), Positives = 89/192 (46%), Gaps = 21/192 (10%)
Query: 101 DLQAQSK--GNPEQTPVLKPEEEAPAPEVGASKPEGI---DSRPETLHP--GRPQ-PPAE 152
DLQ K G P++ P P P S P + RP+ P GRP P A+
Sbjct: 282 DLQGIQKIYGPPDKIP--PPTRPLPTVPPHRSIPPADPRKNDRPKPPRPPTGRPSYPGAK 339
Query: 153 EELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDAAFT 211
+C G F+ L+ +F F+ Q+ + + V GYP I W G+ IDA +
Sbjct: 340 PNICDGN-FNTLAILRR-EMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDAVYE 397
Query: 212 RINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDN-VDAALALPAHSYSGRER 270
N G FKG++YW F+D L P YP ++ GIP + +D+A+ + +
Sbjct: 398 --NSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAI-----WWEDVGK 450
Query: 271 VYFFKGKQYWEY 282
YFFKG +YW Y
Sbjct: 451 TYFFKGDRYWRY 462
Score = 65.9 bits (159), Expect = 8e-11
Identities = 40/128 (31%), Positives = 69/128 (53%), Gaps = 11/128 (8%)
Query: 162 DAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGP--IDAAFTRINCQGKT 219
DA + +G+ F+G + + ++PGYP + + P ID+A + GKT
Sbjct: 393 DAVYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAIWWEDV-GKT 451
Query: 220 YLFKGSQYWRFEDGV--LDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGK 277
Y FKG +YWR+ + + +DP YP+ I+ + GIP++ A + ++ YF+KGK
Sbjct: 452 YFFKGDRYWRYSEEMKTMDPGYPKPIT-VWKGIPESPQGAFVHKENGFT-----YFYKGK 505
Query: 278 QYWEYQFQ 285
+YW++ Q
Sbjct: 506 EYWKFNNQ 513
Score = 52.8 bits (125), Expect = 7e-07
Identities = 36/108 (33%), Positives = 50/108 (46%), Gaps = 18/108 (16%)
Query: 170 GSLFAFRGQ--YCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQY 227
G + F+G + Y + K + PGYPK I GI AF G TY +KG +Y
Sbjct: 449 GKTYFFKGDRYWRYSEEMKTMDPGYPKPITVWKGIPESPQGAFVHKE-NGFTYFYKGKEY 507
Query: 228 WRFEDGVL--DPDYPRNISDGFDGI-------------PDNVDAALAL 260
W+F + +L +P YPR+I F G PD+VD + L
Sbjct: 508 WKFNNQILKVEPGYPRSILKDFMGCDGPTDRVKEGHSPPDDVDIVIKL 555
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/71 (29%), Positives = 39/71 (54%), Gaps = 3/71 (4%)
Query: 140 ETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEK--AVRPGYPK-LI 196
+T+ PG P+P + P AF +NG + ++G+ ++ + + V PGYP+ ++
Sbjct: 467 KTMDPGYPKPITVWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQILKVEPGYPRSIL 526
Query: 197 RDVWGIEGPID 207
+D G +GP D
Sbjct: 527 KDFMGCDGPTD 537
Score = 34.7 bits (78), Expect = 0.20
Identities = 16/43 (37%), Positives = 24/43 (55%), Gaps = 4/43 (9%)
Query: 431 EPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCP 473
E + +FF GD+Y+R + + T+DP YP+ I W G P
Sbjct: 446 EDVGKTYFFKGDRYWRY---SEEMKTMDPGYPKPIT-VWKGIP 484
Score = 34.7 bits (78), Expect = 0.20
Identities = 14/39 (35%), Positives = 25/39 (64%), Gaps = 3/39 (7%)
Query: 437 FFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAP 475
+F+ G +Y++ N ++ V+P YPRSI + ++GC P
Sbjct: 500 YFYKGKEYWKFN---NQILKVEPGYPRSILKDFMGCDGP 535
>gi|5729929 matrix metalloproteinase 24 preproprotein [Homo sapiens]
Length = 645
Score = 79.3 bits (194), Expect = 7e-15
Identities = 50/175 (28%), Positives = 81/175 (46%), Gaps = 20/175 (11%)
Query: 119 EEEAPAPEVGASKPEGIDSRPETLHPGRPQPP---------AEEELCSGKPFDAFTDLKN 169
E P P + + R P P+PP + +C G F+ L
Sbjct: 334 EPTRPLPTLPVRRIHSPSERKHERQPRPPRPPLGDRPSTPGTKPNICDGN-FNTVA-LFR 391
Query: 170 GSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYW 228
G +F F+ ++ + L V+ GYP I W G+ IDAA+ R + G+ FKG +YW
Sbjct: 392 GEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERAD--GRFVFFKGDKYW 449
Query: 229 RFEDGVLDPDYPRNISDGFDGIP-DNVDAALALPAHSYSGRERVYFFKGKQYWEY 282
F++ ++P YP ++ + +P + +D AL + + YFFKG++YW Y
Sbjct: 450 VFKEVTVEPGYPHSLGELGSCLPREGIDTAL-----RWEPVGKTYFFKGERYWRY 499
Score = 65.9 bits (159), Expect = 8e-11
Identities = 49/144 (34%), Positives = 67/144 (46%), Gaps = 15/144 (10%)
Query: 149 PPAEEELCSGKP--FDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGI---E 203
P E+ G P DA + +G F+G + E V PGYP + ++ E
Sbjct: 415 PMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPRE 474
Query: 204 GPIDAAFTRINCQGKTYLFKGSQYWRF--EDGVLDPDYPRNISDGFDGIPDNVDAALALP 261
G ID A R GKTY FKG +YWR+ E DP YP+ I+ + GIP A
Sbjct: 475 G-IDTAL-RWEPVGKTYFFKGERYWRYSEERRATDPGYPKPIT-VWKGIPQAPQGAFISK 531
Query: 262 AHSYSGRERVYFFKGKQYWEYQFQ 285
Y+ YF+KG+ YW++ Q
Sbjct: 532 EGYYT-----YFYKGRDYWKFDNQ 550
Score = 43.1 bits (100), Expect = 6e-04
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 6/68 (8%)
Query: 216 QGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFK 275
+G+ ++FK +WR + + YP I + G+P +DAA R FFK
Sbjct: 391 RGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYE------RADGRFVFFK 444
Query: 276 GKQYWEYQ 283
G +YW ++
Sbjct: 445 GDKYWVFK 452
Score = 34.3 bits (77), Expect = 0.26
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 4/43 (9%)
Query: 431 EPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCP 473
EP+ +FF G++Y+R + R DP YP+ I W G P
Sbjct: 483 EPVGKTYFFKGERYWRYSEERR---ATDPGYPKPIT-VWKGIP 521
Score = 30.8 bits (68), Expect = 2.8
Identities = 12/36 (33%), Positives = 23/36 (63%), Gaps = 3/36 (8%)
Query: 437 FFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGC 472
+F+ G Y++ + + +V+P YPR+I + W+GC
Sbjct: 537 YFYKGRDYWKFDNQKL---SVEPGYPRNILRDWMGC 569
>gi|4505211 matrix metalloproteinase 15 preproprotein [Homo sapiens]
Length = 669
Score = 76.6 bits (187), Expect = 4e-14
Identities = 56/199 (28%), Positives = 88/199 (44%), Gaps = 33/199 (16%)
Query: 113 TPVLKPEEEAPAPEVGASKPEGIDSRP-----------ETLHPGRPQPPAEEE------- 154
TP +P+ P P V +P D RP + P +P PP +
Sbjct: 305 TPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQ 364
Query: 155 ----LCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDAA 209
+C G FD L+ G +F F+G++ + + V YP I W G+ G I AA
Sbjct: 365 YGPNICDGD-FDTVAMLR-GEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAA 422
Query: 210 FTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIP-DNVDAALALPAHSYSGR 268
+ R + G+ FKG +YW F + L+P YP+ ++ GIP D +D A+ +
Sbjct: 423 YERQD--GRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAI-----WWEPT 475
Query: 269 ERVYFFKGKQYWEYQFQHQ 287
+FF+ +YW + + Q
Sbjct: 476 GHTFFFQEDRYWRFNEETQ 494
Score = 56.6 bits (135), Expect = 5e-08
Identities = 42/126 (33%), Positives = 59/126 (46%), Gaps = 11/126 (8%)
Query: 138 RPETLHPGRPQPPAEEELCSGKPFDAFTDL----KNGSLFAFRGQYCYELDEKAVR--PG 191
R L PG PQP L G P+D G F F+ + +E+ R PG
Sbjct: 442 REANLEPGYPQPLTSYGL--GIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPG 499
Query: 192 YPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVL--DPDYPRNISDGFDG 249
YPK I GI AF N TY +KG++YW+F++ L +P YP++I F G
Sbjct: 500 YPKPISVWQGIPASPKGAFLS-NDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMG 558
Query: 250 IPDNVD 255
++V+
Sbjct: 559 CQEHVE 564
Score = 37.4 bits (85), Expect = 0.030
Identities = 20/44 (45%), Positives = 25/44 (56%), Gaps = 4/44 (9%)
Query: 431 EPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPA 474
EP FFF D+Y+R N T+R DP YP+ I+ W G PA
Sbjct: 473 EPTGHTFFFQEDRYWRFNEETQR---GDPGYPKPIS-VWQGIPA 512
Score = 29.6 bits (65), Expect = 6.3
Identities = 12/36 (33%), Positives = 23/36 (63%), Gaps = 3/36 (8%)
Query: 437 FFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGC 472
+F+ G KY++ + R++ P YP+SI + ++GC
Sbjct: 527 YFYKGTKYWKFDNERLRME---PGYPKSILRDFMGC 559
>gi|4505209 matrix metalloproteinase 13 preproprotein [Homo sapiens]
Length = 471
Score = 68.9 bits (167), Expect = 9e-12
Identities = 41/115 (35%), Positives = 61/115 (53%), Gaps = 12/115 (10%)
Query: 172 LFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQ--GKTYLFKGSQYWR 229
+F FRG+ + L+ + GYPK I ++ G+ + ++ + GKT LF G+Q WR
Sbjct: 346 IFIFRGRKFWALNGYDILEGYPKKISEL-GLPKEVKKISAAVHFEDTGKTLLFSGNQVWR 404
Query: 230 FEDG--VLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEY 282
++D ++D DYPR I + F GI D VDA Y +YFF G +EY
Sbjct: 405 YDDTNHIMDKDYPRLIEEDFPGIGDKVDAV-------YEKNGYIYFFNGPIQFEY 452
Score = 34.7 bits (78), Expect = 0.20
Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 6/65 (9%)
Query: 216 QGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFK 275
+G+T +FK +WR +D + S + +P+ +DAA P+H + ++ F+
Sbjct: 297 RGETMIFKDRFFWRLHPQQVDAELFLTKSF-WPELPNRIDAAYEHPSH-----DLIFIFR 350
Query: 276 GKQYW 280
G+++W
Sbjct: 351 GRKFW 355
>gi|58331148 matrix metalloproteinase 11 preproprotein [Homo
sapiens]
Length = 488
Score = 67.0 bits (162), Expect = 4e-11
Identities = 46/138 (33%), Positives = 70/138 (50%), Gaps = 15/138 (10%)
Query: 148 QPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPI 206
+P A + C FDA + ++ G LF F+ + + L ++PGYP L W G+ P+
Sbjct: 286 EPDAPPDACEAS-FDAVSTIR-GELFFFKAGFVWRLRGGQLQPGYPALASRHWQGLPSPV 343
Query: 207 DAAFTRINCQGKTYLFKGSQYWRF--EDGVLDPDYPRNISDGFDGIPDNVDAALALPAHS 264
DAAF + QG + F+G+QYW + E VL P + G P V AAL
Sbjct: 344 DAAFE--DAQGHIWFFQGAQYWVYDGEKPVLGPAPLTEL--GLVRFP--VHAALVWGPE- 396
Query: 265 YSGRERVYFFKGKQYWEY 282
+ ++YFF+G+ YW +
Sbjct: 397 ---KNKIYFFRGRDYWRF 411
Score = 56.6 bits (135), Expect = 5e-08
Identities = 49/175 (28%), Positives = 71/175 (40%), Gaps = 20/175 (11%)
Query: 183 LDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRN 242
+D + P P D E DA T +G+ + FK WR G L P YP
Sbjct: 277 IDTNEIAPLEPDAPPDA--CEASFDAVST---IRGELFFFKAGFVWRLRGGQLQPGYPAL 331
Query: 243 ISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVF 302
S + G+P VDAA + ++FF+G QYW Y + +P + L V
Sbjct: 332 ASRHWQGLPSPVDAAFE------DAQGHIWFFQGAQYWVYDGE-KPVLGPAPLTELGLVR 384
Query: 303 --EHFAMMQRDSWEDIFELL---FWGRTSAGTRQPQFISR---DWHGVPGQVDAA 349
H A++ I+ +W + R + R DW GVP ++DAA
Sbjct: 385 FPVHAALVWGPEKNKIYFFRGRDYWRFHPSTRRVDSPVPRRATDWRGVPSEIDAA 439
Score = 31.2 bits (69), Expect = 2.2
Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 4/39 (10%)
Query: 436 VFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPA 474
++FF G Y+R + TRRVD+ P PR A W G P+
Sbjct: 400 IYFFRGRDYWRFHPSTRRVDS---PVPRR-ATDWRGVPS 434
>gi|112382270 matrix metalloproteinase 17 preproprotein [Homo
sapiens]
Length = 603
Score = 66.2 bits (160), Expect = 6e-11
Identities = 78/284 (27%), Positives = 116/284 (40%), Gaps = 43/284 (15%)
Query: 113 TPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSL 172
+P +PEE PE P+ S P P + P CS FDA ++ G
Sbjct: 301 SPTAQPEEPPLLPE----PPDNRSSAP----PRKDVP----HRCSTH-FDAVAQIR-GEA 346
Query: 173 FAFRGQYCYELD-EKAVRPGYPKLIRDVW-GIE---GPIDAAFTRINCQGKTYLFKGSQY 227
F F+G+Y + L ++ + P + W G+ +DA + R + K FKG +Y
Sbjct: 347 FFFKGKYFWRLTRDRHLVSLQPAQMHRFWRGLPLHLDSVDAVYERTS-DHKIVFFKGDRY 405
Query: 228 WRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQ 287
W F+D ++ YPR +SD F P +DAA S++ +R YFFK + YW Y +
Sbjct: 406 WVFKDNNVEEGYPRPVSD-FSLPPGGIDAAF-----SWAHNDRTYFFKDQLYWRYDDHTR 459
Query: 288 ------PSQEECEGSSLSAVFEHFAMMQRDSWEDIFE-LLFW----GRTSAGTRQPQFIS 336
P+Q S + + AM D F +W G PQ +
Sbjct: 460 HMDPGYPAQSPLWRGVPSTLDD--AMRWSDGASYFFRGQEYWKVLDGELEVAPGYPQSTA 517
Query: 337 RDWHGV-PGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKGY 379
RDW Q D ++A + A P Q + R+ GY
Sbjct: 518 RDWLVCGDSQADGSVAAGV---DAAEGPRAPPGQHDQSRSEDGY 558
>gi|4505213 matrix metalloproteinase 19 isoform rasi-1 preproprotein
[Homo sapiens]
Length = 508
Score = 63.2 bits (152), Expect = 5e-10
Identities = 64/258 (24%), Positives = 110/258 (42%), Gaps = 47/258 (18%)
Query: 111 EQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNG 170
+++PV++ EEE ++ T+ P +P + CS + DA G
Sbjct: 257 KKSPVIRDEEEE-------------ETELPTVPPVPTEPSPMPDPCSSE-LDAMMLGPRG 302
Query: 171 SLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWR 229
+AF+G Y + + + PG + +W G+ G +DAA Q + FKG + WR
Sbjct: 303 KTYAFKGDYVWTVSDSG--PGPLFRVSALWEGLPGNLDAAVYSPRTQW-IHFFKGDKVWR 359
Query: 230 FEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEY------Q 283
+ + + P +P+ + + + N+DAAL P + ++V+ FKG YW++
Sbjct: 360 YINFKMSPGFPKKL----NRVEPNLDAALYWPLN-----QKVFLFKGSGYWQWDELARTD 410
Query: 284 FQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQ--------PQFI 335
F P + +G + A M SW+D F G+ Q P+ I
Sbjct: 411 FSSYP--KPIKGLFTGVPNQPSAAM---SWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNI 465
Query: 336 SRDW-HGVPGQVDAAMAG 352
S +W H P +D +G
Sbjct: 466 SHNWMHCRPRTIDTTPSG 483
Score = 34.3 bits (77), Expect = 0.26
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 4/37 (10%)
Query: 436 VFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGC 472
V+FF G Y+R+N + R V+ YPR+I+ W+ C
Sbjct: 440 VYFFKGKVYWRLNQQLR----VEKGYPRNISHNWMHC 472
>gi|11321561 hemopexin precursor [Homo sapiens]
Length = 462
Score = 61.6 bits (148), Expect = 1e-09
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 9/136 (6%)
Query: 146 RPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEG 204
+P P E G FDA T NG++ F+G++ ++ K R +LI + W
Sbjct: 41 KPDPDVTERCSDGWSFDATTLDDNGTMLFFKGEFVWK-SHKWDR----ELISERWKNFPS 95
Query: 205 PIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHS 264
P+DAAF + + +L KG + W + + YP+ + D F GIP +DAA+
Sbjct: 96 PVDAAFRQGH--NSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGE 153
Query: 265 YSGRERVYFFKGKQYW 280
E V FF+G + W
Sbjct: 154 CQA-EGVLFFQGDREW 168
Score = 40.8 bits (94), Expect = 0.003
Identities = 36/137 (26%), Positives = 53/137 (38%), Gaps = 45/137 (32%)
Query: 160 PFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDAAFT--RINCQ 216
P DA + S+F +G + + GYPKL++D + GI P+DAA R CQ
Sbjct: 96 PVDAAFRQGHNSVFLIKGDKVWVYPPEKKEKGYPKLLQDEFPGIPSPLDAAVECHRGECQ 155
Query: 217 ----------------------------------------GKTYLFKGSQYWRFED--GV 234
G+ Y F+G+Q+ RF+ G
Sbjct: 156 AEGVLFFQGDREWFWDLATGTMKERSWPAVGNCSSALRWLGRYYCFQGNQFLRFDPVRGE 215
Query: 235 LDPDYPRNISDGFDGIP 251
+ P YPR++ D F P
Sbjct: 216 VPPRYPRDVRDYFMPCP 232
Score = 31.2 bits (69), Expect = 2.2
Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 8/66 (12%)
Query: 217 GKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKG 276
G TY F G+ YWR D D + I+ + P VDAA +S E++Y +G
Sbjct: 272 GATYAFSGTHYWRL-DTSRDGWHSWPIAHQWPQGPSAVDAA-------FSWEEKLYLVQG 323
Query: 277 KQYWEY 282
Q + +
Sbjct: 324 TQVYVF 329
Score = 29.6 bits (65), Expect = 6.3
Identities = 10/21 (47%), Positives = 13/21 (61%)
Query: 457 VDPPYPRSIAQYWLGCPAPGH 477
V P YPR + Y++ CP GH
Sbjct: 216 VPPRYPRDVRDYFMPCPGRGH 236
>gi|4505221 matrix metalloproteinase 8 preproprotein [Homo sapiens]
Length = 467
Score = 60.5 bits (145), Expect = 3e-09
Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 10/122 (8%)
Query: 163 AFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLF 222
A+ D +F F+G + L + GYPK I + +G + A + + KTY F
Sbjct: 332 AYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDISN-YGFPSSVQAIDAAVFYRSKTYFF 390
Query: 223 KGSQYWRFEDG--VLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYW 280
Q+WR+++ ++P YP++IS F GI VDA + + F G +Y+
Sbjct: 391 VNDQFWRYDNQRQFMEPGYPKSISGAFPGIESKVDAV-------FQQEHFFHVFSGPRYY 443
Query: 281 EY 282
+
Sbjct: 444 AF 445
Score = 52.4 bits (124), Expect = 9e-07
Identities = 44/148 (29%), Positives = 67/148 (45%), Gaps = 13/148 (8%)
Query: 143 HPGRPQPPAEEELCSGK-PFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW- 200
+P +P P+ + C FDA T L+ LF F+ +Y + + R I W
Sbjct: 266 NPIQPTGPSTPKPCDPSLTFDAITTLRGEILF-FKDRYFWRRHPQLQRVEM-NFISLFWP 323
Query: 201 GIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISD-GFDGIPDNVDAALA 259
+ I AA+ + + +LFKG+QYW + YP++IS+ GF +DAA+
Sbjct: 324 SLPTGIQAAYEDFD-RDLIFLFKGNQYWALSGYDILQGYPKDISNYGFPSSVQAIDAAVF 382
Query: 260 LPAHSYSGRERVYFFKGKQYWEYQFQHQ 287
R + YFF Q+W Y Q Q
Sbjct: 383 Y-------RSKTYFFVNDQFWRYDNQRQ 403
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 60.1 bits (144), Expect = 4e-09
Identities = 38/116 (32%), Positives = 61/116 (52%), Gaps = 12/116 (10%)
Query: 175 FRGQYCYELDEKAVRPGYPKLIRDVWGIEGPI---DAAFTRINCQGKTYLFKGSQYWRFE 231
F G + + GYPK + + G+ + DAAF + KTY+F G ++WR+
Sbjct: 485 FAGNEYWIYSASTLERGYPKPLTSL-GLPPDVQRVDAAFNWSKNK-KTYIFAGDKFWRYN 542
Query: 232 D--GVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQ 285
+ +DP +P+ I+D ++ IPDN+DA + L +S YFFKG Y + + Q
Sbjct: 543 EVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHS-----YFFKGAYYLKLENQ 593
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 8/135 (5%)
Query: 150 PAEEELCSGK-PFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWG-IEGPID 207
P E+C FD ++ G +F F+ ++ + +P P L+ W + ID
Sbjct: 413 PVTPEICKQDIVFDGIAQIR-GEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKID 471
Query: 208 AAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSG 267
A + + K F G++YW + L+ YP+ ++ G+P +V A A ++S
Sbjct: 472 AVYEAPQ-EEKAVFFAGNEYWIYSASTLERGYPKPLTS--LGLPPDVQRVDA--AFNWSK 526
Query: 268 RERVYFFKGKQYWEY 282
++ Y F G ++W Y
Sbjct: 527 NKKTYIFAGDKFWRY 541
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 14/101 (13%)
Query: 141 TLHPGRPQPPAEEELCSGKPFD------AFTDLKNGSLFAFRGQYCYELDE--KAVRPGY 192
TL G P+P G P D AF KN + F G + +E K + PG+
Sbjct: 497 TLERGYPKPLTS----LGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGF 552
Query: 193 PKLIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWRFED 232
PKLI D W I +DA + G +Y FKG+ Y + E+
Sbjct: 553 PKLIADAWNAIPDNLDAV-VDLQGGGHSYFFKGAYYLKLEN 592
Score = 30.8 bits (68), Expect = 2.8
Identities = 13/40 (32%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Query: 434 QSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCP 473
+ + F+GDK++R N ++ +DP +P+ IA W P
Sbjct: 528 KKTYIFAGDKFWRYNEVKKK---MDPGFPKLIADAWNAIP 564
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 60.1 bits (144), Expect = 4e-09
Identities = 38/116 (32%), Positives = 61/116 (52%), Gaps = 12/116 (10%)
Query: 175 FRGQYCYELDEKAVRPGYPKLIRDVWGIEGPI---DAAFTRINCQGKTYLFKGSQYWRFE 231
F G + + GYPK + + G+ + DAAF + KTY+F G ++WR+
Sbjct: 535 FAGNEYWIYSASTLERGYPKPLTSL-GLPPDVQRVDAAFNWSKNK-KTYIFAGDKFWRYN 592
Query: 232 D--GVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQ 285
+ +DP +P+ I+D ++ IPDN+DA + L +S YFFKG Y + + Q
Sbjct: 593 EVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHS-----YFFKGAYYLKLENQ 643
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 8/135 (5%)
Query: 150 PAEEELCSGK-PFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWG-IEGPID 207
P E+C FD ++ G +F F+ ++ + +P P L+ W + ID
Sbjct: 463 PVTPEICKQDIVFDGIAQIR-GEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKID 521
Query: 208 AAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSG 267
A + + K F G++YW + L+ YP+ ++ G+P +V A A ++S
Sbjct: 522 AVYEAPQ-EEKAVFFAGNEYWIYSASTLERGYPKPLTS--LGLPPDVQRVDA--AFNWSK 576
Query: 268 RERVYFFKGKQYWEY 282
++ Y F G ++W Y
Sbjct: 577 NKKTYIFAGDKFWRY 591
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/101 (33%), Positives = 46/101 (45%), Gaps = 14/101 (13%)
Query: 141 TLHPGRPQPPAEEELCSGKPFD------AFTDLKNGSLFAFRGQYCYELDE--KAVRPGY 192
TL G P+P G P D AF KN + F G + +E K + PG+
Sbjct: 547 TLERGYPKPLTS----LGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGF 602
Query: 193 PKLIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWRFED 232
PKLI D W I +DA + G +Y FKG+ Y + E+
Sbjct: 603 PKLIADAWNAIPDNLDAV-VDLQGGGHSYFFKGAYYLKLEN 642
Score = 30.8 bits (68), Expect = 2.8
Identities = 13/40 (32%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Query: 434 QSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCP 473
+ + F+GDK++R N ++ +DP +P+ IA W P
Sbjct: 578 KKTYIFAGDKFWRYNEVKKK---MDPGFPKLIADAWNAIP 614
>gi|11968059 matrix metalloproteinase 25 preproprotein [Homo
sapiens]
Length = 562
Score = 58.9 bits (141), Expect = 1e-08
Identities = 45/158 (28%), Positives = 69/158 (43%), Gaps = 20/158 (12%)
Query: 131 KPEG--IDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAV 188
+P G + RP LH PA+ + A+ ++G + F G + ++ +
Sbjct: 343 QPSGQLVSPRPARLHRFWEGLPAQVRVVQA----AYARHRDGRILLFSGPQFWVFQDRQL 398
Query: 189 RPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVL--DPDYPRNIS-- 244
G L +DA F+ GKTYL +G QYWR+++ DP YPR++S
Sbjct: 399 EGGARPLTELGLPPGEEVDAVFSWPQ-NGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLW 457
Query: 245 DGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEY 282
+G PD+V + S YFFKG YW +
Sbjct: 458 EGAPPSPDDV---------TVSNAGDTYFFKGAHYWRF 486
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 6/82 (7%)
Query: 203 EGPIDAAFTRINCQGKTYLFKGSQYWRFE-DGVLDPDYPRNISDGFDGIPDNVDAALALP 261
EG DA N +G+T+ FKG +WR + G L P + ++G+P V A
Sbjct: 318 EGNFDAI---ANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAY 374
Query: 262 AHSYSGRERVYFFKGKQYWEYQ 283
A G R+ F G Q+W +Q
Sbjct: 375 ARHRDG--RILLFSGPQFWVFQ 394
Score = 29.6 bits (65), Expect = 6.3
Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 437 FFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAP 475
+FF G Y+R + + + P P+ + WL CPAP
Sbjct: 476 YFFKGAHYWRFPKNSIKTE---PDAPQPMGPNWLDCPAP 511
>gi|73858572 matrix metalloproteinase 12 preproprotein [Homo
sapiens]
Length = 470
Score = 58.2 bits (139), Expect = 2e-08
Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 11/117 (9%)
Query: 172 LFAFRGQYCYELDEKAVRPGYPKLIRDVW--GIEGPIDAAFTRINCQGKTYLFKGSQYWR 229
+F F+ + + P YPK I IDAA +TY F +QYWR
Sbjct: 344 VFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFY-RTYFFVDNQYWR 402
Query: 230 FEDG--VLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQF 284
+++ ++DP YP+ I+ F GI +DA YS + YFF+G +EY F
Sbjct: 403 YDERRQMMDPGYPKLITKNFQGIGPKIDAVF------YSKNKYYYFFQGSNQFEYDF 453
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/145 (30%), Positives = 69/145 (47%), Gaps = 12/145 (8%)
Query: 147 PQPP-AEEELCSGK-PFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWG-IE 203
P P +E LC FDA T + N +F F+ ++ + + + LI +W +
Sbjct: 272 PNPDNSEPALCDPNLSFDAVTTVGN-KIFFFKDRFFWLKVSERPKTSV-NLISSLWPTLP 329
Query: 204 GPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNI-SDGFDGIPDNVDAALALPA 262
I+AA+ I + + +LFK +YW + +P+YP++I S GF +DAA+ P
Sbjct: 330 SGIEAAY-EIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPR 388
Query: 263 HSYSGRERVYFFKGKQYWEYQFQHQ 287
R YFF QYW Y + Q
Sbjct: 389 F-----YRTYFFVDNQYWRYDERRQ 408
>gi|4505217 matrix metalloproteinase 3 preproprotein [Homo sapiens]
Length = 477
Score = 57.0 bits (136), Expect = 4e-08
Identities = 52/183 (28%), Positives = 81/183 (44%), Gaps = 24/183 (13%)
Query: 139 PET-LHPGRPQPPAEEELCSGKP---FDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPK 194
PET L P P PP + P FDA + L+ G + F+ ++ + + + P
Sbjct: 270 PETPLVPTEPVPPEPGTPANCDPALSFDAVSTLR-GEILIFKDRHFWRKSLRKLEPEL-H 327
Query: 195 LIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISD-GFDGIPD 252
LI W + +DAA+ + + ++FKG+Q+W + YPR I GF
Sbjct: 328 LISSFWPSLPSGVDAAY-EVTSKDLVFIFKGNQFWAIRGNEVRAGYPRGIHTLGFPPTVR 386
Query: 253 NVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQ------PSQ--EECEG--SSLSAVF 302
+DAA+ S + + YFF +YW + + P Q E+ G S + AVF
Sbjct: 387 KIDAAI-----SDKEKNKTYFFVEDKYWRFDEKRNSMEPGFPKQIAEDFPGIDSKIDAVF 441
Query: 303 EHF 305
E F
Sbjct: 442 EEF 444
>gi|4505205 matrix metalloproteinase 10 preproprotein [Homo sapiens]
Length = 476
Score = 55.5 bits (132), Expect = 1e-07
Identities = 43/160 (26%), Positives = 70/160 (43%), Gaps = 13/160 (8%)
Query: 137 SRPETLHPGRPQPPAEEELCSGKP---FDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYP 193
S E L P + P E P FDA + L+ LF F+ +Y + P +
Sbjct: 268 STEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLF-FKDRYFWRRSHWNPEPEF- 325
Query: 194 KLIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISD-GFDGIP 251
LI W + +DAA+ +N + ++FKG+++W + YPR I GF
Sbjct: 326 HLISAFWPSLPSYLDAAY-EVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTI 384
Query: 252 DNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQE 291
+DAA+ S +++ YFF +YW + Q ++
Sbjct: 385 RKIDAAV-----SDKEKKKTYFFAADKYWRFDENSQSMEQ 419
Score = 50.8 bits (120), Expect = 3e-06
Identities = 36/116 (31%), Positives = 57/116 (49%), Gaps = 12/116 (10%)
Query: 171 SLFAFRGQYCYELDEKAVRPGYPKLIRDVW--GIEGPIDAAFTRINCQGKTYLFKGSQYW 228
++F F+G + + V+ GYP+ I + IDAA + + KTY F +YW
Sbjct: 350 TVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKE-KKKTYFFAADKYW 408
Query: 229 RFEDGV--LDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEY 282
RF++ ++ +PR I+D F G+ VDA L A + YFF G +E+
Sbjct: 409 RFDENSQSMEQGFPRLIADDFPGVEPKVDA--VLQAFGF-----FYFFSGSSQFEF 457
>gi|22218341 matrix metalloproteinase 21 preproprotein [Homo
sapiens]
Length = 569
Score = 48.5 bits (114), Expect = 1e-05
Identities = 42/119 (35%), Positives = 56/119 (47%), Gaps = 20/119 (16%)
Query: 171 SLFAFRGQY--CYELDEKAVRPGYPKLIRDVW-GIEGPIDAAFTRINC--QGKTYLFKGS 225
S + FR + YE R G P I W GI AF I + + Y F+G+
Sbjct: 355 STYFFRNSWYWLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYFFQGN 414
Query: 226 QYWRFE---DGVLDPD-----YPRNISDGFDGIPDNVDAALALPAHSYSGRER-VYFFK 275
QYWR++ D L D YP+ IS+GF GIP +D A Y R++ +YFFK
Sbjct: 415 QYWRYDSDKDQALTEDEQGKSYPKLISEGFPGIPSPLDTAF------YDRRQKLIYFFK 467
Score = 47.0 bits (110), Expect = 4e-05
Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 18/119 (15%)
Query: 194 KLIRDVWG-IEGPIDAAFTRI----NCQGK------TYLFKGSQYWRFEDGVLDPDY--P 240
K I+ ++G EG D AF I N G+ TY F+ S YW +E+ Y P
Sbjct: 320 KAIQKLYGSCEGSFDTAFDWIRKERNQYGEVMVRFSTYFFRNSWYWLYENRNNRTRYGDP 379
Query: 241 RNISDGFDGIPD-NVDAALALPAHSYSGRERVYFFKGKQYWEYQF-QHQPSQEECEGSS 297
I G+ GIP N+DA + + R+ YFF+G QYW Y + Q E+ +G S
Sbjct: 380 IQILTGWPGIPTHNIDAFVHIWTWK---RDERYFFQGNQYWRYDSDKDQALTEDEQGKS 435
Score = 41.6 bits (96), Expect = 0.002
Identities = 41/136 (30%), Positives = 59/136 (43%), Gaps = 18/136 (13%)
Query: 162 DAFTDL---KNGSLFAFRGQYCYELD--------EKAVRPGYPKLIRDVW-GIEGPIDAA 209
DAF + K + F+G + D E YPKLI + + GI P+D A
Sbjct: 395 DAFVHIWTWKRDERYFFQGNQYWRYDSDKDQALTEDEQGKSYPKLISEGFPGIPSPLDTA 454
Query: 210 FTRINCQGKTYLFKGSQYWRFE---DGVLDPDYPRNISDGFDG-IPDNVDAALALPAHSY 265
F Q Y FK S + F+ + VL+ YP+ I++ F IP N A+
Sbjct: 455 FYDRR-QKLIYFFKESLVFAFDVNRNRVLN-SYPKRITEVFPAVIPQNHPFRNIDSAYYS 512
Query: 266 SGRERVYFFKGKQYWE 281
++FFKG YW+
Sbjct: 513 YAYNSIFFFKGNAYWK 528
>gi|13236530 matrix metalloproteinase 28 isoform 1 preproprotein
[Homo sapiens]
Length = 520
Score = 48.1 bits (113), Expect = 2e-05
Identities = 45/150 (30%), Positives = 67/150 (44%), Gaps = 22/150 (14%)
Query: 132 PEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPG 191
P+G RPET P + C FDA T + L+ F+G + +E+
Sbjct: 311 PQG--RRPETQGP---------KYCHSS-FDAITVDRQQQLYIFKGSHFWEVAADG-NVS 357
Query: 192 YPKLIRDVW-GIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGI 250
P+ +++ W G+ I+AA +N G Y FKG + WRF P+ G G+
Sbjct: 358 EPRPLQERWVGLPPNIEAAAVSLN-DGDFYFFKGGRCWRFRGPKPVWGLPQLCRAG--GL 414
Query: 251 PDNVDAALALPAHSYSGRERVYFFKGKQYW 280
P + DAAL P R+ FKG +Y+
Sbjct: 415 PRHPDAALFFPP-----LRRLILFKGARYY 439
Score = 39.7 bits (91), Expect = 0.006
Identities = 24/72 (33%), Positives = 41/72 (56%), Gaps = 8/72 (11%)
Query: 213 INCQGKTYLFKGSQYWRF-EDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERV 271
++ Q + Y+FKGS +W DG + PR + + + G+P N++AA A S + +
Sbjct: 333 VDRQQQLYIFKGSHFWEVAADG--NVSEPRPLQERWVGLPPNIEAA----AVSLNDGD-F 385
Query: 272 YFFKGKQYWEYQ 283
YFFKG + W ++
Sbjct: 386 YFFKGGRCWRFR 397
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 4/66 (6%)
Query: 172 LFAFRGQYCYELDEKA--VRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWR 229
L F+G Y L V P YP+ ++D GI + A R + G F+ +YWR
Sbjct: 430 LILFKGARYYVLARGGLQVEPYYPRSLQDWGGIPEEVSGALPRPD--GSIIFFRDDRYWR 487
Query: 230 FEDGVL 235
+ L
Sbjct: 488 LDQAKL 493
>gi|73808268 matrix metalloproteinase 27 [Homo sapiens]
Length = 513
Score = 48.1 bits (113), Expect = 2e-05
Identities = 44/144 (30%), Positives = 62/144 (43%), Gaps = 22/144 (15%)
Query: 147 PQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEG-- 204
P PA+ + P D K+ + + RG AV P YPK I + G G
Sbjct: 323 PSLPADLQAAYENPRDKILVFKDENFWMIRGY--------AVLPDYPKSIHTL-GFPGRV 373
Query: 205 -PIDAAFTRINCQGKTYLFKGSQYWRFED--GVLDPDYPRNISDGFDGIPDNVDAALALP 261
IDAA + KTY F G WRF++ +D +P+ + F GI VDAA
Sbjct: 374 KKIDAAVCDKTTR-KTYFFVGIWCWRFDEMTQTMDKGFPQRVVKHFPGISIRVDAAF--- 429
Query: 262 AHSYSGRERVYFFKGKQYWEYQFQ 285
Y G +F +G + +EY +
Sbjct: 430 --QYKG--FFFFSRGSKQFEYDIK 449
Score = 47.0 bits (110), Expect = 4e-05
Identities = 37/142 (26%), Positives = 61/142 (42%), Gaps = 12/142 (8%)
Query: 144 PGRPQPPAEEELCSGK-PFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVW-G 201
P +P+ P C FDA T + +F F+G++ + + + +LI W
Sbjct: 267 PAKPKEPTIPHACDPDLTFDAITTFRREVMF-FKGRHLWRIYYDITDVEF-ELIASFWPS 324
Query: 202 IEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISD-GFDGIPDNVDAALAL 260
+ + AA+ N + K +FK +W + PDYP++I GF G +DAA+
Sbjct: 325 LPADLQAAYE--NPRDKILVFKDENFWMIRGYAVLPDYPKSIHTLGFPGRVKKIDAAVC- 381
Query: 261 PAHSYSGRERVYFFKGKQYWEY 282
+ YFF G W +
Sbjct: 382 ----DKTTRKTYFFVGIWCWRF 399
>gi|74272287 matrix metalloproteinase 9 preproprotein [Homo sapiens]
Length = 707
Score = 47.0 bits (110), Expect = 4e-05
Identities = 50/185 (27%), Positives = 74/185 (40%), Gaps = 20/185 (10%)
Query: 110 PEQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGR----PQPPAEEELCSGKPFDAFT 165
P P + P E A G P + P T P P P ++ C+ FDA
Sbjct: 469 PTGPPTVHPSERPTAGPTGP--PSAGPTGPPTAGPSTATTVPLSPVDDA-CNVNIFDAIA 525
Query: 166 DLKNGSLFAFR-GQYCYELDEKAVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYLFK 223
++ N L+ F+ G+Y + + RP P LI D W + +D+ F K + F
Sbjct: 526 EIGN-QLYLFKDGKYWRFSEGRGSRPQGPFLIADKWPALPRKLDSVFEE-RLSKKLFFFS 583
Query: 224 GSQYWRFED-GVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEY 282
G Q W + VL P + G D V AL SGR ++ F G++ W +
Sbjct: 584 GRQVWVYTGASVLGPRRLDKLGLGAD--VAQVTGALR------SGRGKMLLFSGRRLWRF 635
Query: 283 QFQHQ 287
+ Q
Sbjct: 636 DVKAQ 640
>gi|45359865 matrix metalloproteinase 20 preproprotein [Homo
sapiens]
Length = 483
Score = 47.0 bits (110), Expect = 4e-05
Identities = 42/165 (25%), Positives = 74/165 (44%), Gaps = 22/165 (13%)
Query: 138 RPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIR 197
RP T+ PQ + + A+ + G+ + F+G + Y + G P+ I
Sbjct: 332 RPSTITSSFPQLMSNVDA-------AYEVAERGTAYFFKGPH-YWITRGFQMQGPPRTIY 383
Query: 198 DVWGIEG---PIDAAFTRINCQGKTYLFKGSQYWRFEDGV--LDPDYPRNISDGFDGIPD 252
D +G IDAA Q KT F G +Y+ +++ ++ DYP+N + F G+
Sbjct: 384 D-FGFPRHVQQIDAAVYLREPQ-KTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNG 441
Query: 253 NVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSS 297
+DAA+ L + +YFF G + ++Y + + + SS
Sbjct: 442 QIDAAVELNGY-------IYFFSGPKTYKYDTEKEDVVSVVKSSS 479
Score = 40.8 bits (94), Expect = 0.003
Identities = 42/159 (26%), Positives = 64/159 (40%), Gaps = 15/159 (9%)
Query: 208 AAFTRINCQGKTYL-FKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYS 266
++F + GK L FK +WR + + P I+ F + NVDA A+ +
Sbjct: 300 SSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDA-----AYEVA 354
Query: 267 GRERVYFFKGKQYW---EYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIF----EL 319
R YFFKG YW +Q Q P G A+ R+ + +F E
Sbjct: 355 ERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEY 414
Query: 320 LFWGRTSAGTRQ--PQFISRDWHGVPGQVDAAMAGRIYI 356
+ + P+ ++ GV GQ+DAA+ YI
Sbjct: 415 YSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYI 453
>gi|5174623 placental protein 11 precursor [Homo sapiens]
Length = 369
Score = 44.7 bits (104), Expect = 2e-04
Identities = 19/78 (24%), Positives = 38/78 (48%), Gaps = 8/78 (10%)
Query: 23 SCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQ--------VTRGDVFTMPEDE 74
SC+GRC E F+ +C C+ C + +CC D+ + C +T+ ++ ++ E
Sbjct: 48 SCQGRCYEAFDKHHQCHCNARCQEFGNCCKDFESLCSDHEVSHSSDAITKEEIQSISEKI 107
Query: 75 YTVYDDGEEKNNATVHEQ 92
Y + +K + ++ Q
Sbjct: 108 YRADTNKAQKEDIVLNSQ 125
>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
Length = 888
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 3/54 (5%)
Query: 6 PLLILALLAWVALADQESCKGRCTEGFNVDKK-CQCDELCSYYQSCCTDYTAEC 58
P +L+ W ++ SCKGRC E C+CD LC Y SCC D+ C
Sbjct: 43 PPTVLSDSPWTNISG--SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
Score = 37.4 bits (85), Expect = 0.030
Identities = 16/38 (42%), Positives = 18/38 (47%)
Query: 22 ESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECK 59
E K RC E N + C C E C CCT+Y CK
Sbjct: 102 ECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
Length = 863
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 3/54 (5%)
Query: 6 PLLILALLAWVALADQESCKGRCTEGFNVDKK-CQCDELCSYYQSCCTDYTAEC 58
P +L+ W ++ SCKGRC E C+CD LC Y SCC D+ C
Sbjct: 43 PPTVLSDSPWTNISG--SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
Score = 37.4 bits (85), Expect = 0.030
Identities = 16/38 (42%), Positives = 18/38 (47%)
Query: 22 ESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECK 59
E K RC E N + C C E C CCT+Y CK
Sbjct: 102 ECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
>gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]
Length = 915
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 3/54 (5%)
Query: 6 PLLILALLAWVALADQESCKGRCTEGFNVDKK-CQCDELCSYYQSCCTDYTAEC 58
P +L+ W ++ SCKGRC E C+CD LC Y SCC D+ C
Sbjct: 43 PPTVLSDSPWTNISG--SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
Score = 37.4 bits (85), Expect = 0.030
Identities = 16/38 (42%), Positives = 18/38 (47%)
Query: 22 ESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECK 59
E K RC E N + C C E C CCT+Y CK
Sbjct: 102 ECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,331,282
Number of Sequences: 37866
Number of extensions: 1193295
Number of successful extensions: 4696
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 75
Number of HSP's that attempted gapping in prelim test: 4285
Number of HSP's gapped (non-prelim): 335
length of query: 478
length of database: 18,247,518
effective HSP length: 106
effective length of query: 372
effective length of database: 14,233,722
effective search space: 5294944584
effective search space used: 5294944584
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.